WorldWideScience

Sample records for method step index

  1. A step-defined sedentary lifestyle index: <5000 steps/day.

    Science.gov (United States)

    Tudor-Locke, Catrine; Craig, Cora L; Thyfault, John P; Spence, John C

    2013-02-01

    Step counting (using pedometers or accelerometers) is widely accepted by researchers, practitioners, and the general public. Given the mounting evidence of the link between low steps/day and time spent in sedentary behaviours, how few steps/day some populations actually perform, and the growing interest in the potentially deleterious effects of excessive sedentary behaviours on health, an emerging question is "How many steps/day are too few?" This review examines the utility, appropriateness, and limitations of using a reoccurring candidate for a step-defined sedentary lifestyle index: 10 000) to lower (sedentary lifestyle index for adults is appropriate for researchers and practitioners and for communicating with the general public. There is little evidence to advocate any specific value indicative of a step-defined sedentary lifestyle index in children and adolescents.

  2. Step-indexed Kripke models over recursive worlds

    DEFF Research Database (Denmark)

    Birkedal, Lars; Reus, Bernhard; Schwinghammer, Jan

    2011-01-01

    worlds that are recursively defined in a category of metric spaces. In this paper, we broaden the scope of this technique from the original domain-theoretic setting to an elementary, operational one based on step indexing. The resulting method is widely applicable and leads to simple, succinct models...

  3. Computing discharge using the index velocity method

    Science.gov (United States)

    Levesque, Victor A.; Oberg, Kevin A.

    2012-01-01

    techniques in which the mean cross-sectional velocity for the standard section is related to the measured index velocity. Most ratings are simple-linear regressions, but more complex ratings may be necessary in some cases. Once the rating is established, validation measurements should be made periodically. Over time, validation measurements may provide additional definition to the rating or result in the creation of a new rating. The computation of discharge is the last step in the index velocity method, and in some ways it is the most straight-forward step. This step differs little from the steps used to compute discharge records for stage-discharge gaging stations. The ratings are entered into database software used for records computation, and continuous records of discharge are computed.

  4. Method of identifying features in indexed data

    Science.gov (United States)

    Jarman, Kristin H [Richland, WA; Daly, Don Simone [Richland, WA; Anderson, Kevin K [Richland, WA; Wahl, Karen L [Richland, WA

    2001-06-26

    The present invention is a method of identifying features in indexed data, especially useful for distinguishing signal from noise in data provided as a plurality of ordered pairs. Each of the plurality of ordered pairs has an index and a response. The method has the steps of: (a) providing an index window having a first window end located on a first index and extending across a plurality of indices to a second window end; (b) selecting responses corresponding to the plurality of indices within the index window and computing a measure of dispersion of the responses; and (c) comparing the measure of dispersion to a dispersion critical value. Advantages of the present invention include minimizing signal to noise ratio, signal drift, varying baseline signal and combinations thereof.

  5. Humidity insensitive step-index polymer optical fibre Bragg grating sensors

    DEFF Research Database (Denmark)

    Woyessa, Getinet; Fasano, Andrea; Stefani, Alessio

    2015-01-01

    We have fabricated and characterised a humidity insensitive step index(SI) polymer optical fibre(POF) Bragg grating sensors. The fibre was made based on the injection molding technique, which is an efficient method for fast, flexible and cost effective preparation of the fibre preform. The fabric...... poly-methyl-methacrylate (PMMA) based SIPOFs. The fibre has a minimum loss of similar to 6dB/m at 770nm....

  6. Step-Indexed Relational Reasoning for Countable Nondeterminism

    DEFF Research Database (Denmark)

    Birkedal, Lars; Bizjak, Aleš; Schwinghamme, Jan

    2013-01-01

    for programming languages with countable nondeterminism is challenging. We present a step-indexed logical relations model of a higher-order functional programming language with countable nondeterminism and demonstrate how it can be used to reason about contextually defined may- and must-equivalence. In earlier...

  7. Analysis of circular fibers with an arbitrary index profile by the Galerkin method.

    Science.gov (United States)

    Guo, Shangping; Wu, Feng; Ikram, Khalid; Albin, Sacharia

    2004-01-01

    We propose a full-vectorial Galerkin method for the analysis of circular symmetric fibers with arbitrary index profiles. A set of orthogonal Laguerre-Gauss functions is used to calculate the dispersion relation and mode fields of TE and TM modes. Examples are given for both standard step-index fibers and Bragg fibers. For standard step-index fiber with low or high index contrast, the Galerkin method agrees well with the analytical results. In the case of the TE mode of a Bragg fiber it agrees well with the asymptotic results.

  8. Free Modal Algebras Revisited: The Step-by-Step Method

    NARCIS (Netherlands)

    Bezhanishvili, N.; Ghilardi, Silvio; Jibladze, Mamuka

    2012-01-01

    We review the step-by-step method of constructing finitely generated free modal algebras. First we discuss the global step-by-step method, which works well for rank one modal logics. Next we refine the global step-by-step method to obtain the local step-by-step method, which is applicable beyond

  9. Single mode step-index polymer optical fiber for humidity insensitive high temperature fiber Bragg grating sensors

    DEFF Research Database (Denmark)

    Woyessa, Getinet; Fasano, Andrea; Stefani, Alessio

    2016-01-01

    We have fabricated the first single-mode step-index and humidity insensitive polymer optical fiber operating in the 850 nm wavelength ranges. The step-index preform is fabricated using injection molding, which is an efficient method for cost effective, flexible and fast preparation of the fiber...... preform. The fabricated single-mode step-index (SI) polymer optical fiber (POF) has a 4.8µm core made from TOPAS grade 5013S-04 with a glass transition temperature of 134°C and a 150 µm cladding made from ZEONEX grade 480R with a glass transition temperature of 138°C. The key advantages of the proposed...... SIPOF are low water absorption, high operating temperature and chemical inertness to acids and bases and many polar solvents as compared to the conventional poly-methyl-methacrylate (PMMA) and polystyrene based POFs. In addition, the fiber Bragg grating writing time is short compared to microstructured...

  10. Flexible biodegradable citrate-based polymeric step-index optical fiber.

    Science.gov (United States)

    Shan, Dingying; Zhang, Chenji; Kalaba, Surge; Mehta, Nikhil; Kim, Gloria B; Liu, Zhiwen; Yang, Jian

    2017-10-01

    Implanting fiber optical waveguides into tissue or organs for light delivery and collection is among the most effective ways to overcome the issue of tissue turbidity, a long-standing obstacle for biomedical optical technologies. Here, we report a citrate-based material platform with engineerable opto-mechano-biological properties and demonstrate a new type of biodegradable, biocompatible, and low-loss step-index optical fiber for organ-scale light delivery and collection. By leveraging the rich designability and processibility of citrate-based biodegradable polymers, two exemplary biodegradable elastomers with a fine refractive index difference and yet matched mechanical properties and biodegradation profiles were developed. Furthermore, we developed a two-step fabrication method to fabricate flexible and low-loss (0.4 db/cm) optical fibers, and performed systematic characterizations to study optical, spectroscopic, mechanical, and biodegradable properties. In addition, we demonstrated the proof of concept of image transmission through the citrate-based polymeric optical fibers and conducted in vivo deep tissue light delivery and fluorescence sensing in a Sprague-Dawley (SD) rat, laying the groundwork for realizing future implantable devices for long-term implantation where deep-tissue light delivery, sensing and imaging are desired, such as cell, tissue, and scaffold imaging in regenerative medicine and in vivo optogenetic stimulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. AN EFFICIENT ANALYSIS FOR ABSORPTION AND GAIN COEFFICIENTS IN 'SINGLE STEP-INDEX WAVEGUIDE'S BY USING THE ALPHA METHOD

    Directory of Open Access Journals (Sweden)

    Mustafa TEMİZ

    2008-02-01

    Full Text Available In this study, some design parameters such as normalized frequency and especially normalized propagation constant have been obtained, depending on some parameters which are functions of energy eigenvalues of the carriers such as electrons and holes confined in a single step-index waveguide laser (SSIWGL or single stepindex waveguide (SSIWG. Some optical expressions about the optical power and probability quantities for the active region and cladding layers of the SSIWG or SSIWGL have been investigated. Investigations have been undertaken in terms of these parameters and also individually the optical even and odd electric field waves with the lowest-modes were theoretically computed. Especially absorption coefficients and loss coefficients addition to some important quantities of the single step-index waveguide lasers for the even and odd electric field waves are evaluated.

  12. New method for calculating the coupling coefficient in graded index optical fibers

    Science.gov (United States)

    Savović, Svetislav; Djordjevich, Alexandar

    2018-05-01

    A simple method is proposed for determining the mode coupling coefficient D in graded index multimode optical fibers. It only requires observation of the output modal power distribution P(m, z) for one fiber length z as the Gaussian launching modal power distribution changes, with the Gaussian input light distribution centered along the graded index optical fiber axis (θ0 = 0) without radial offset (r0 = 0). A similar method we previously proposed for calculating the coupling coefficient D in a step-index multimode optical fibers where the output angular power distributions P(θ, z) for one fiber length z with the Gaussian input light distribution launched centrally along the step-index optical fiber axis (θ0 = 0) is needed to be known.

  13. Genomic prediction for Nordic Red Cattle using one-step and selection index blending

    DEFF Research Database (Denmark)

    Guosheng, Su; Madsen, Per; Nielsen, Ulrik Sander

    2012-01-01

    This study investigated the accuracy of direct genomic breeding values (DGV) using a genomic BLUP model, genomic enhanced breeding values (GEBV) using a one-step blending approach, and GEBV using a selection index blending approach for 15 traits of Nordic Red Cattle. The data comprised 6,631 bulls...... genotyped and nongenotyped bulls for one-step blending, and to scale DGV and its expected reliability in the selection index blending. Weighting (scaling) factors had a small influence on reliabilities of GEBV, but a large influence on the variation of GEBV. Based on the validation analyses, averaged over...... the 15 traits, the reliability of DGV for bulls without daughter records was 11.0 percentage points higher than the reliability of conventional pedigree index. Further gain of 0.9 percentage points was achieved by combining information from conventional pedigree index using the selection index blending...

  14. A Step-indexed Semantic Model of Types for the Call-by-Name Lambda Calculus

    OpenAIRE

    Meurer, Benedikt

    2011-01-01

    Step-indexed semantic models of types were proposed as an alternative to purely syntactic safety proofs using subject-reduction. Building upon the work by Appel and others, we introduce a generalized step-indexed model for the call-by-name lambda calculus. We also show how to prove type safety of general recursion in our call-by-name model.

  15. The analogy between photonic crystal fibres and step index fibres

    DEFF Research Database (Denmark)

    Birks, T.A.; Mogilevtsev, D.; Knight, J.C.

    1999-01-01

    The propagation constant of a photonic crystal fiber (PCF) can be approximated by substituting the effective V-value and NA into a formula valid for step index fibers (SIF), provided the V-value is defined with a core radius of 0.625 $Lambda@. V$PRM and NA must still be computed. Care must be taken...

  16. Valve cam design using numerical step-by-step method

    OpenAIRE

    Vasilyev, Aleksandr; Bakhracheva, Yuliya; Kabore, Ousman; Zelenskiy, Yuriy

    2014-01-01

    This article studies the numerical step-by-step method of cam profile design. The results of the study are used for designing the internal combustion engine valve gear. This method allows to profile the peak efficiency of cams in view of many restrictions, connected with valve gear serviceability and reliability.

  17. Stimulated Brillouin scattering continuous wave phase conjugation in step-index fiber optics.

    Science.gov (United States)

    Massey, Steven M; Spring, Justin B; Russell, Timothy H

    2008-07-21

    Continuous wave (CW) stimulated Brillouin scattering (SBS) phase conjugation in step-index optical fibers was studied experimentally and modeled as a function of fiber length. A phase conjugate fidelity over 80% was measured from SBS in a 40 m fiber using a pinhole technique. Fidelity decreases with fiber length, and a fiber with a numerical aperture (NA) of 0.06 was found to generate good phase conjugation fidelity over longer lengths than a fiber with 0.13 NA. Modeling and experiment support previous work showing the maximum interaction length which yields a high fidelity phase conjugate beam is inversely proportional to the fiber NA(2), but find that fidelity remains high over much longer fiber lengths than previous models calculated. Conditions for SBS beam cleanup in step-index fibers are discussed.

  18. Fluorescence imaging of lattice re-distribution on step-index direct laser written Nd:YAG waveguide lasers

    Energy Technology Data Exchange (ETDEWEB)

    Martínez de Mendívil, Jon; Pérez Delgado, Alberto; Lifante, Ginés; Jaque, Daniel [Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid 28049 (Spain); Ródenas, Airán [Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, Tarragona 43007 (Spain); Institute of Photonics and Quantum Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Benayas, Antonio, E-mail: antonio.benayas@emt.inrs.ca [Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid 28049 (Spain); Institut National de la Recherche Scientifique, Centre – Énergie Matériaux et Télécommunications, 1650, Boul. Lionel Boulet Varennes, Quebec J3X 1S2 (Canada); Aguiló, Magdalena; Diaz, Francesc [Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, Tarragona 43007 (Spain); Kar, Ajoy K. [Institute of Photonics and Quantum Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom)

    2015-01-14

    The laser performance and crystalline micro-structural properties of near-infrared step-index channel waveguides fabricated inside Neodymium doped YAG laser ceramics by means of three-dimensional sub-picosecond pulse laser direct writing are reported. Fluorescence micro-mapping of the waveguide cross-sections reveals that an essential crystal lattice re-distribution has been induced after short pulse irradiation. Such lattice re-distribution is evidenced at the waveguide core corresponding to the laser written refractive index increased volume. The waveguides core surroundings also present diverse changes including slight lattice disorder and bi-axial strain fields. The step-index waveguide laser performance is compared with previous laser fabricated waveguides with a stress-optic guiding mechanism in absence of laser induced lattice re-distribution.

  19. Highly reflective Bragg gratings in slightly etched step-index polymer optical fiber.

    Science.gov (United States)

    Hu, Xuehao; Pun, Chi-Fung Jeff; Tam, Hwa-Yaw; Mégret, Patrice; Caucheteur, Christophe

    2014-07-28

    During the past few years, a strong progress has been made in the photo-writing of fiber Bragg gratings (FBGs) in polymer optical fibers (POFs), animated by the constant wish to enhance the grating reflectivity and improve the sensing performances. In this paper, we report the photo-inscription of highly reflective gratings in step-index POFs, obtained thanks to a slight etching of the cladding. We demonstrate that a cladding diameter decrease of ~12% is an ideal trade-off to produce highly reflective gratings with enhanced axial strain sensitivity, while keeping almost intact their mechanical resistance. For this, we make use of Trans-4-stilbenemethanol-doped photosensitive step-index poly(methyl methacrylate) (PMMA) POFs. FBGs are inscribed at ~1550 nm by the scanning phase mask technique in POFs of different external diameters. Reflectivity reaching 97% is achieved for 6 mm long FBGs, compared to 25% for non-etched POFs. We also report that a cladding decrease enhances the FBG axial tension while keeping unchanged temperature and surrounding refractive index sensitivities. Finally and for the first time, a measurement is conducted in transmission with polarized light, showing that a photo-induced birefringence of 7 × 10(-6) is generated (one order of magnitude higher than the intrinsic fiber birefringence), which is similar to the one generated in silica fiber using ultra-violet laser.

  20. Is a step in the primordial spectral index favoured by CMB data?

    International Nuclear Information System (INIS)

    Joy, Minu; Shafieloo, Arman; Sahni, Varun; Starobinsky, Alexei A.

    2009-01-01

    A sudden small change in the second derivative of the inflaton potential can result in a universal local feature in the spectrum of primordial perturbations generated during inflation. The exact solution describing this feature \\cite(minu) is characterized by a step in the spectral index modulated by characteristic oscillations and results in a large running of the spectral index localized over a few e-folds of scale. In this paper we confront this step-like feature with the 5 year WMAP results and demonstrate that it provides a better fit to this data than a featureless initial spectrum. If such a feature exists at all, then it should lie at sufficiently large scales k 0 ∼ −1 corresponding to l ∼ s localized near this scale. This feature could arise as a result of a 'mini-waterfall'-type fast second order phase transition experienced by an auxiliary heavy field during inflation, in a model similar to hybrid inflation (though for a different choice of parameters). If this is the case, then the auxiliary field should be positively coupled to the inflaton

  1. Mid-infrared supercontinuum generation spanning more than 11 μm in a chalcogenide step-index fiber

    DEFF Research Database (Denmark)

    Petersen, Christian Rosenberg; Møller, Uffe Visbech; Kubat, Irnis

    2015-01-01

    Supercontinuum generation covering an ultra-broad spectrum from 1.5-11.7μm and 1.4-13.3μm is experimentally demonstrated by pumping an 85mm chalcogenide step-index fiber with 100fs pulses at a wavelength of 4.5μm and 6.3μm, respectively.......Supercontinuum generation covering an ultra-broad spectrum from 1.5-11.7μm and 1.4-13.3μm is experimentally demonstrated by pumping an 85mm chalcogenide step-index fiber with 100fs pulses at a wavelength of 4.5μm and 6.3μm, respectively....

  2. Walk Ratio (Step Length/Cadence) as a Summary Index of Neuromotor Control of Gait: Application to Multiple Sclerosis

    Science.gov (United States)

    Rota, Viviana; Perucca, Laura; Simone, Anna; Tesio, Luigi

    2011-01-01

    In healthy adults, the step length/cadence ratio [walk ratio (WR) in mm/(steps/min) and normalized for height] is known to be constant around 6.5 mm/(step/min). It is a speed-independent index of the overall neuromotor gait control, in as much as it reflects energy expenditure, balance, between-step variability, and attentional demand. The speed…

  3. Step by step parallel programming method for molecular dynamics code

    International Nuclear Information System (INIS)

    Orii, Shigeo; Ohta, Toshio

    1996-07-01

    Parallel programming for a numerical simulation program of molecular dynamics is carried out with a step-by-step programming technique using the two phase method. As a result, within the range of a certain computing parameters, it is found to obtain parallel performance by using the level of parallel programming which decomposes the calculation according to indices of do-loops into each processor on the vector parallel computer VPP500 and the scalar parallel computer Paragon. It is also found that VPP500 shows parallel performance in wider range computing parameters. The reason is that the time cost of the program parts, which can not be reduced by the do-loop level of the parallel programming, can be reduced to the negligible level by the vectorization. After that, the time consuming parts of the program are concentrated on less parts that can be accelerated by the do-loop level of the parallel programming. This report shows the step-by-step parallel programming method and the parallel performance of the molecular dynamics code on VPP500 and Paragon. (author)

  4. Index Fund Selections with GAs and Classifications Based on Turnover

    Science.gov (United States)

    Orito, Yukiko; Motoyama, Takaaki; Yamazaki, Genji

    It is well known that index fund selections are important for the risk hedge of investment in a stock market. The`selection’means that for`stock index futures’, n companies of all ones in the market are selected. For index fund selections, Orito et al.(6) proposed a method consisting of the following two steps : Step 1 is to select N companies in the market with a heuristic rule based on the coefficient of determination between the return rate of each company in the market and the increasing rate of the stock price index. Step 2 is to construct a group of n companies by applying genetic algorithms to the set of N companies. We note that the rule of Step 1 is not unique. The accuracy of the results using their method depends on the length of time data (price data) in the experiments. The main purpose of this paper is to introduce a more`effective rule’for Step 1. The rule is based on turnover. The method consisting of Step 1 based on turnover and Step 2 is examined with numerical experiments for the 1st Section of Tokyo Stock Exchange. The results show that with our method, it is possible to construct the more effective index fund than the results of Orito et al.(6). The accuracy of the results using our method depends little on the length of time data (turnover data). The method especially works well when the increasing rate of the stock price index over a period can be viewed as a linear time series data.

  5. Is a step in the primordial spectral index favoured by CMB data?

    Energy Technology Data Exchange (ETDEWEB)

    Joy, Minu; Shafieloo, Arman; Sahni, Varun [Inter-University Centre for Astronomy and Astrophysics, Pune 411 007 (India); Starobinsky, Alexei A., E-mail: minujoy@alphonsacollege.ac.in, E-mail: a.shafieloo1@physics.ox.ac.uk, E-mail: varun@iucaa.ernet.in, E-mail: alstar@landau.ac.ru [Landau Institute for Theoretical Physics, 119334 Moscow (Russian Federation)

    2009-06-01

    A sudden small change in the second derivative of the inflaton potential can result in a universal local feature in the spectrum of primordial perturbations generated during inflation. The exact solution describing this feature \\cite(minu) is characterized by a step in the spectral index modulated by characteristic oscillations and results in a large running of the spectral index localized over a few e-folds of scale. In this paper we confront this step-like feature with the 5 year WMAP results and demonstrate that it provides a better fit to this data than a featureless initial spectrum. If such a feature exists at all, then it should lie at sufficiently large scales k{sub 0} ∼< 0.003 Mpc{sup −1} corresponding to l ∼< 40. The sign of the effect is shown to correspond to the negative running of n{sub s} localized near this scale. This feature could arise as a result of a 'mini-waterfall'-type fast second order phase transition experienced by an auxiliary heavy field during inflation, in a model similar to hybrid inflation (though for a different choice of parameters). If this is the case, then the auxiliary field should be positively coupled to the inflaton.

  6. A Comparison of body mass index and daily step numbers of secondary school and high school students according to age and gender

    Directory of Open Access Journals (Sweden)

    Özcan Saygın

    2017-12-01

    Full Text Available Aim: The purpose of this study is to compare the body mass index and daily steps number of secondary and high school students in Mugla region according to age and gender. Material and Methods: A total of 1851 volunteer students (682 secondary school students and 1169 high school students participated in this study. Physical activity level was determined by measuring daily step numbers of students with a pedometer. Body mass index (kg/m2 was calculated by utilizing from height and weight measurements in order to find body composition. Acquired data was recorded in SPSS (18.0 program. In order to find a difference in body composition and physical activity level between gender, Independent t-test was applied. One-way Anova was applied in order to find the differences among ages. Tukey HSD Analysis was used to find from which age the difference stemmed from. Frequencies and percentages values were calculated to assess the number of daily steps and body mass index standards, and chi-square analysis was used to find differences according to sex. Results: As a result of the statistical analyse; statistically significant difference was found in the physical activity level of secondary school students, it was also found both high school student’s body composition and physical activity levels of high school students according to gender (p<0.05. While the body mass index values of both male and female students tend to increase with age, the physical activity level of both students tends to decrease with age. Statistically, a significant difference was found when the daily step count standards were compared by sex (X2=23.999 p=0.000. It was found that 65.91% (n=698 of the female students and 49.87% (n=395 of the male students were below the normal values of the daily step counts. Statistically, a significant difference was found when the body mass index standards were compared by sex (X2=15.702, p=0.000. It was seen that 16.90% of female students (n=179

  7. 150 Mb/s wifi transmission over 50m large core diameter step index POF

    NARCIS (Netherlands)

    Shi, Y.; Nieto Munoz, M.; Okonkwo, C.M.; Boom, van den H.P.A.; Tangdiongga, E.; Koonen, A.M.J.

    2011-01-01

    We demonstrate successful transmission of WiFi signals over 50m step-index plastic optical fibre with 1mm core diameter employing an eye-safe resonant cavity light emitting diode and an avalanche photodetector. The EVM performance of 4.1% at signal data rate of 150Mb/s is achieved.

  8. Two-step Raman spectroscopy method for tumor diagnosis

    Science.gov (United States)

    Zakharov, V. P.; Bratchenko, I. A.; Kozlov, S. V.; Moryatov, A. A.; Myakinin, O. O.; Artemyev, D. N.

    2014-05-01

    Two-step Raman spectroscopy phase method was proposed for differential diagnosis of malignant tumor in skin and lung tissue. It includes detection of malignant tumor in healthy tissue on first step with identification of concrete cancer type on the second step. Proposed phase method analyze spectral intensity alteration in 1300-1340 and 1640-1680 cm-1 Raman bands in relation to the intensity of the 1450 cm-1 band on first step, and relative differences between RS intensities for tumor area and healthy skin closely adjacent to the lesion on the second step. It was tested more than 40 ex vivo samples of lung tissue and more than 50 in vivo skin tumors. Linear Discriminant Analysis, Quadratic Discriminant Analysis and Support Vector Machine were used for tumors type classification on phase planes. It is shown that two-step phase method allows to reach 88.9% sensitivity and 87.8% specificity for malignant melanoma diagnosis (skin cancer); 100% sensitivity and 81.5% specificity for adenocarcinoma diagnosis (lung cancer); 90.9% sensitivity and 77.8% specificity for squamous cell carcinoma diagnosis (lung cancer).

  9. Multilevel and Multi-index Monte Carlo methods for the McKean–Vlasov equation

    KAUST Repository

    Haji-Ali, Abdul-Lateef

    2017-09-12

    We address the approximation of functionals depending on a system of particles, described by stochastic differential equations (SDEs), in the mean-field limit when the number of particles approaches infinity. This problem is equivalent to estimating the weak solution of the limiting McKean–Vlasov SDE. To that end, our approach uses systems with finite numbers of particles and a time-stepping scheme. In this case, there are two discretization parameters: the number of time steps and the number of particles. Based on these two parameters, we consider different variants of the Monte Carlo and Multilevel Monte Carlo (MLMC) methods and show that, in the best case, the optimal work complexity of MLMC, to estimate the functional in one typical setting with an error tolerance of $$\\\\mathrm {TOL}$$TOL, is when using the partitioning estimator and the Milstein time-stepping scheme. We also consider a method that uses the recent Multi-index Monte Carlo method and show an improved work complexity in the same typical setting of . Our numerical experiments are carried out on the so-called Kuramoto model, a system of coupled oscillators.

  10. Research note: Grazing-index method procedures of vegetation ...

    African Journals Online (AJOL)

    In the past, veld condition in the Karoo was assessed using the ecological index methods. This recently changed to the graxing-index method on account of the of the differently estimated grazing-index values being used. The principles governing the method of survey remain the same. The method employs ...

  11. Application of Nemerow Index Method and Integrated Water Quality Index Method in Water Quality Assessment of Zhangze Reservoir

    Science.gov (United States)

    Zhang, Qian; Feng, Minquan; Hao, Xiaoyan

    2018-03-01

    [Objective] Based on the water quality historical data from the Zhangze Reservoir from the last five years, the water quality was assessed by the integrated water quality identification index method and the Nemerow pollution index method. The results of different evaluation methods were analyzed and compared and the characteristics of each method were identified.[Methods] The suitability of the water quality assessment methods were compared and analyzed, based on these results.[Results] the water quality tended to decrease over time with 2016 being the year with the worst water quality. The sections with the worst water quality were the southern and northern sections.[Conclusion] The results produced by the traditional Nemerow index method fluctuated greatly in each section of water quality monitoring and therefore could not effectively reveal the trend of water quality at each section. The combination of qualitative and quantitative measures of the comprehensive pollution index identification method meant it could evaluate the degree of water pollution as well as determine that the river water was black and odorous. However, the evaluation results showed that the water pollution was relatively low.The results from the improved Nemerow index evaluation were better as the single indicators and evaluation results are in strong agreement; therefore the method is able to objectively reflect the water quality of each water quality monitoring section and is more suitable for the water quality evaluation of the reservoir.

  12. Strong Stability Preserving Explicit Linear Multistep Methods with Variable Step Size

    KAUST Repository

    Hadjimichael, Yiannis

    2016-09-08

    Strong stability preserving (SSP) methods are designed primarily for time integration of nonlinear hyperbolic PDEs, for which the permissible SSP step size varies from one step to the next. We develop the first SSP linear multistep methods (of order two and three) with variable step size, and prove their optimality, stability, and convergence. The choice of step size for multistep SSP methods is an interesting problem because the allowable step size depends on the SSP coefficient, which in turn depends on the chosen step sizes. The description of the methods includes an optimal step-size strategy. We prove sharp upper bounds on the allowable step size for explicit SSP linear multistep methods and show the existence of methods with arbitrarily high order of accuracy. The effectiveness of the methods is demonstrated through numerical examples.

  13. New methods for indexing multi-lattice diffraction data

    International Nuclear Information System (INIS)

    Gildea, Richard J.; Waterman, David G.; Parkhurst, James M.; Axford, Danny; Sutton, Geoff; Stuart, David I.; Sauter, Nicholas K.; Evans, Gwyndaf; Winter, Graeme

    2014-01-01

    A new indexing method is presented which is capable of indexing multiple crystal lattices from narrow wedges of data. The efficacy of this method is demonstrated with both semi-synthetic multi-lattice data and real multi-lattice data recorded from microcrystals of ∼1 µm in size. A new indexing method is presented which is capable of indexing multiple crystal lattices from narrow wedges of diffraction data. The method takes advantage of a simplification of Fourier transform-based methods that is applicable when the unit-cell dimensions are known a priori. The efficacy of this method is demonstrated with both semi-synthetic multi-lattice data and real multi-lattice data recorded from crystals of ∼1 µm in size, where it is shown that up to six lattices can be successfully indexed and subsequently integrated from a 1° wedge of data. Analysis is presented which shows that improvements in data-quality indicators can be obtained through accurate identification and rejection of overlapping reflections prior to scaling

  14. A step-indexed Kripke model of hidden state via recursive properties on recursively defined metric spaces

    DEFF Research Database (Denmark)

    Birkedal, Lars; Schwinghammer, Jan; Støvring, Kristian

    2010-01-01

    for Chargu´eraud and Pottier’s type and capability system including frame and anti-frame rules, based on the operational semantics and step-indexed heap relations. The worlds are constructed as a recursively defined predicate on a recursively defined metric space, which provides a considerably simpler...

  15. Improved perovskite phototransistor prepared using multi-step annealing method

    Science.gov (United States)

    Cao, Mingxuan; Zhang, Yating; Yu, Yu; Yao, Jianquan

    2018-02-01

    Organic-inorganic hybrid perovskites with good intrinsic physical properties have received substantial interest for solar cell and optoelectronic applications. However, perovskite film always suffers from a low carrier mobility due to its structural imperfection including sharp grain boundaries and pinholes, restricting their device performance and application potential. Here we demonstrate a straightforward strategy based on multi-step annealing process to improve the performance of perovskite photodetector. Annealing temperature and duration greatly affects the surface morphology and optoelectrical properties of perovskites which determines the device property of phototransistor. The perovskite films treated with multi-step annealing method tend to form highly uniform, well-crystallized and high surface coverage perovskite film, which exhibit stronger ultraviolet-visible absorption and photoluminescence spectrum compare to the perovskites prepared by conventional one-step annealing process. The field-effect mobilities of perovskite photodetector treated by one-step direct annealing method shows mobility as 0.121 (0.062) cm2V-1s-1 for holes (electrons), which increases to 1.01 (0.54) cm2V-1s-1 for that treated with muti-step slow annealing method. Moreover, the perovskite phototransistors exhibit a fast photoresponse speed of 78 μs. In general, this work focuses on the influence of annealing methods on perovskite phototransistor, instead of obtains best parameters of it. These findings prove that Multi-step annealing methods is feasible to prepared high performance based photodetector.

  16. Solving point reactor kinetic equations by time step-size adaptable numerical methods

    International Nuclear Information System (INIS)

    Liao Chaqing

    2007-01-01

    Based on the analysis of effects of time step-size on numerical solutions, this paper showed the necessity of step-size adaptation. Based on the relationship between error and step-size, two-step adaptation methods for solving initial value problems (IVPs) were introduced. They are Two-Step Method and Embedded Runge-Kutta Method. PRKEs were solved by implicit Euler method with step-sizes optimized by using Two-Step Method. It was observed that the control error has important influence on the step-size and the accuracy of solutions. With suitable control errors, the solutions of PRKEs computed by the above mentioned method are accurate reasonably. The accuracy and usage of MATLAB built-in ODE solvers ode23 and ode45, both of which adopt Runge-Kutta-Fehlberg method, were also studied and discussed. (authors)

  17. A Step-Indexed Kripke Model of Hidden State via Recursive Properties on Recursively Defined Metric Spaces

    DEFF Research Database (Denmark)

    Schwinghammer, Jan; Birkedal, Lars; Støvring, Kristian

    2011-01-01

    ´eraud and Pottier’s type and capability system including both frame and anti-frame rules. The model is a possible worlds model based on the operational semantics and step-indexed heap relations, and the worlds are constructed as a recursively defined predicate on a recursively defined metric space. We also extend...

  18. Automated method to compute Evans index for diagnosis of idiopathic normal pressure hydrocephalus on brain CT images

    Science.gov (United States)

    Takahashi, Noriyuki; Kinoshita, Toshibumi; Ohmura, Tomomi; Matsuyama, Eri; Toyoshima, Hideto

    2017-03-01

    The early diagnosis of idiopathic normal pressure hydrocephalus (iNPH) considered as a treatable dementia is important. The iNPH causes enlargement of lateral ventricles (LVs). The degree of the enlargement of the LVs on CT or MR images is evaluated by using a diagnostic imaging criterion, Evans index. Evans index is defined as the ratio of the maximal width of frontal horns (FH) of the LVs to the maximal width of the inner skull (IS). Evans index is the most commonly used parameter for the evaluation of ventricular enlargement. However, manual measurement of Evans index is a time-consuming process. In this study, we present an automated method to compute Evans index on brain CT images. The algorithm of the method consisted of five major steps: standardization of CT data to an atlas, extraction of FH and IS regions, the search for the outmost points of bilateral FH regions, determination of the maximal widths of both the FH and the IS, and calculation of Evans index. The standardization to the atlas was performed by using linear affine transformation and non-linear wrapping techniques. The FH regions were segmented by using a three dimensional region growing technique. This scheme was applied to CT scans from 44 subjects, including 13 iNPH patients. The average difference in Evans index between the proposed method and manual measurement was 0.01 (1.6%), and the correlation coefficient of these data for the Evans index was 0.98. Therefore, this computerized method may have the potential to accurately compute Evans index for the diagnosis of iNPH on CT images.

  19. Comparison of Model Reliabilities from Single-Step and Bivariate Blending Methods

    DEFF Research Database (Denmark)

    Taskinen, Matti; Mäntysaari, Esa; Lidauer, Martin

    2013-01-01

    Model based reliabilities in genetic evaluation are compared between three methods: animal model BLUP, single-step BLUP, and bivariate blending after genomic BLUP. The original bivariate blending is revised in this work to better account animal models. The study data is extracted from...... be calculated. Model reliabilities by the single-step and the bivariate blending methods were higher than by animal model due to genomic information. Compared to the single-step method, the bivariate blending method reliability estimates were, in general, lower. Computationally bivariate blending method was......, on the other hand, lighter than the single-step method....

  20. Strong Stability Preserving Two-step Runge–Kutta Methods

    KAUST Repository

    Ketcheson, David I.; Gottlieb, Sigal; Macdonald, Colin B.

    2011-01-01

    We investigate the strong stability preserving (SSP) property of two-step Runge–Kutta (TSRK) methods. We prove that all SSP TSRK methods belong to a particularly simple subclass of TSRK methods, in which stages from the previous step are not used. We derive simple order conditions for this subclass. Whereas explicit SSP Runge–Kutta methods have order at most four, we prove that explicit SSP TSRK methods have order at most eight. We present explicit TSRK methods of up to eighth order that were found by numerical search. These methods have larger SSP coefficients than any known methods of the same order of accuracy and may be implemented in a form with relatively modest storage requirements. The usefulness of the TSRK methods is demonstrated through numerical examples, including integration of very high order weighted essentially non-oscillatory discretizations.

  1. Strong Stability Preserving Two-step Runge–Kutta Methods

    KAUST Repository

    Ketcheson, David I.

    2011-12-22

    We investigate the strong stability preserving (SSP) property of two-step Runge–Kutta (TSRK) methods. We prove that all SSP TSRK methods belong to a particularly simple subclass of TSRK methods, in which stages from the previous step are not used. We derive simple order conditions for this subclass. Whereas explicit SSP Runge–Kutta methods have order at most four, we prove that explicit SSP TSRK methods have order at most eight. We present explicit TSRK methods of up to eighth order that were found by numerical search. These methods have larger SSP coefficients than any known methods of the same order of accuracy and may be implemented in a form with relatively modest storage requirements. The usefulness of the TSRK methods is demonstrated through numerical examples, including integration of very high order weighted essentially non-oscillatory discretizations.

  2. Methods for semi-automated indexing for high precision information retrieval

    Science.gov (United States)

    Berrios, Daniel C.; Cucina, Russell J.; Fagan, Lawrence M.

    2002-01-01

    OBJECTIVE: To evaluate a new system, ISAID (Internet-based Semi-automated Indexing of Documents), and to generate textbook indexes that are more detailed and more useful to readers. DESIGN: Pilot evaluation: simple, nonrandomized trial comparing ISAID with manual indexing methods. Methods evaluation: randomized, cross-over trial comparing three versions of ISAID and usability survey. PARTICIPANTS: Pilot evaluation: two physicians. Methods evaluation: twelve physicians, each of whom used three different versions of the system for a total of 36 indexing sessions. MEASUREMENTS: Total index term tuples generated per document per minute (TPM), with and without adjustment for concordance with other subjects; inter-indexer consistency; ratings of the usability of the ISAID indexing system. RESULTS: Compared with manual methods, ISAID decreased indexing times greatly. Using three versions of ISAID, inter-indexer consistency ranged from 15% to 65% with a mean of 41%, 31%, and 40% for each of three documents. Subjects using the full version of ISAID were faster (average TPM: 5.6) and had higher rates of concordant index generation. There were substantial learning effects, despite our use of a training/run-in phase. Subjects using the full version of ISAID were much faster by the third indexing session (average TPM: 9.1). There was a statistically significant increase in three-subject concordant indexing rate using the full version of ISAID during the second indexing session (p < 0.05). SUMMARY: Users of the ISAID indexing system create complex, precise, and accurate indexing for full-text documents much faster than users of manual methods. Furthermore, the natural language processing methods that ISAID uses to suggest indexes contributes substantially to increased indexing speed and accuracy.

  3. Two step continuous method to synthesize colloidal spheroid gold nanorods.

    Science.gov (United States)

    Chandra, S; Doran, J; McCormack, S J

    2015-12-01

    This research investigated a two-step continuous process to synthesize colloidal suspension of spheroid gold nanorods. In the first step; gold precursor was reduced to seed-like particles in the presence of polyvinylpyrrolidone and ascorbic acid. In continuous second step; silver nitrate and alkaline sodium hydroxide produced various shape and size Au nanoparticles. The shape was manipulated through weight ratio of ascorbic acid to silver nitrate by varying silver nitrate concentration. The specific weight ratio of 1.35-1.75 grew spheroid gold nanorods of aspect ratio ∼1.85 to ∼2.2. Lower weight ratio of 0.5-1.1 formed spherical nanoparticle. The alkaline medium increased the yield of gold nanorods and reduced reaction time at room temperature. The synthesized gold nanorods retained their shape and size in ethanol. The surface plasmon resonance was red shifted by ∼5 nm due to higher refractive index of ethanol than water. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Effects of ionizing radiation on various core/clad ratio step index pure silica fibers

    International Nuclear Information System (INIS)

    Greenwell, R.A.; Barnes, C.E.; Nelson, G.W.

    1988-01-01

    Radiation testing was performed on polyimide-coated pure-silica-core step-index fibers fabricated from different preform core/clad ratios. Preliminary results indicate that the smaller the core/clad ratio, the better the radiation response of the fiber. These results are fortuitous for space applications, since the polyimide coating is also a low-outgassing wide-temperature-range small-size fiber coating material. The variations in radiation response may be due to a postdrawing anneal occurring during coating cure, which minimizes drawing-induced defects. 8 references

  5. An improved 4-step commutation method application for matrix converter

    DEFF Research Database (Denmark)

    Guo, Yu; Guo, Yougui; Deng, Wenlang

    2014-01-01

    A novel four-step commutation method is proposed for matrix converter cell, 3 phase inputs to 1 phase output in this paper, which is obtained on the analysis of published commutation methods for matrix converter. The first and fourth step can be shorter than the second or third one. The discussed...... method here is implemented by programming in VHDL language. Finally, the novel method in this paper is verified by experiments....

  6. Bragg gratings inscription at 1550 nm in photosensitive step-index polymer optical fiber

    Science.gov (United States)

    Hu, X.; Kinet, D.; Chah, K.; Mégret, Patrice; Caucheteur, C.

    2013-05-01

    In this paper, we report photo-inscription of uniform Bragg gratings in Trans-4-stilbenemethanol-doped photosensitive step-index polymer optical fiber characterized by a core diameter of 8.2 μm. Single-mode gratings were produced at ~1550 nm by the phase mask technique with a Helium-Cadmium emitting at 325 nm with an average power of 30 mW. The grating growth was monitored during the manufacturing process, showing that the reflected band is blue shifted by a few hundreds of picometers. Finally, the gratings were characterized in temperature in the range 25 - 50 °C. Their sensitivity has been computed equal to - 47 pm/°C.

  7. Dynamics of Nonlinear Excitation of the High-Order Mode in a Single-Mode Step-Index Optical Fiber

    Science.gov (United States)

    Burdin, V.; Bourdine, A.

    2018-04-01

    This work is concerned with approximate model of higher-order mode nonlinear excitation in a singlemode silica optical fiber. We present some results of simulation for step-index optical fiber under femtosecond optical pulse launching, which confirm ability of relatively stable higher-order mode excitation in such singlemode optical fiber over sufficiently narrow range of launched optical power variation.

  8. Three-Step Predictor-Corrector of Exponential Fitting Method for Nonlinear Schroedinger Equations

    International Nuclear Information System (INIS)

    Tang Chen; Zhang Fang; Yan Haiqing; Luo Tao; Chen Zhanqing

    2005-01-01

    We develop the three-step explicit and implicit schemes of exponential fitting methods. We use the three-step explicit exponential fitting scheme to predict an approximation, then use the three-step implicit exponential fitting scheme to correct this prediction. This combination is called the three-step predictor-corrector of exponential fitting method. The three-step predictor-corrector of exponential fitting method is applied to numerically compute the coupled nonlinear Schroedinger equation and the nonlinear Schroedinger equation with varying coefficients. The numerical results show that the scheme is highly accurate.

  9. Supervising PTCA treatment with a scheme of steps combination SPECT 99Tcm-MIBI myocardial imaging

    International Nuclear Information System (INIS)

    Luan Zhaosheng; Tian Jiahe; Peng Yong; Zhou Wen; Gai Luyue; Sun Zhijun; Su Yuwen; Liu Xiaohu

    2001-01-01

    Objective: To set up a useful supervising method around PTCA treatment. Methods: A scheme of steps combination SPECT 99 Tc m -MIBI myocardial imaging was devised. 87 patients with coronary artery disease were selected into the study. 3-step imaging, exercise, rest and intravenous infusion of nitroglycerine (NTG) imaging, was performed at 1 week before PTCA. 2-step imaging, exercise and rest imaging, was performed 1-2 weeks after PTCA. All of the indexes obtained from steps combination imaging before and after PTCA were contrasted with each other in pairs. Results: 1) Compared with outcome of clinical assessing, the imaging after PTCA could correctly assess PTCA outcome. 2) The myocardial defects showed in 3-step imaging before PTCA appeared to be ameliorated after PTCA and the amelioration showed in exercise imaging was more evident than that in rest imaging. The myocardial perfusion state revealed by NTG imaging was similar to that revealed by rest imaging after PTCA. 3) The 3-step imaging findings correlated with PTCA outcome, the best correlation was found between indexes of myocardial defect changes showed by NTG and exercise imaging and indexes of PTCA outcome (r = 0.9470, P 99 Tc m -MIBI myocardial SPECT imaging scheme is a very useful supervising method around PTCA. 2-step imaging after PTCA could assess outcome correctly, and 3-step imaging before it could predict outcome correctly, too

  10. A Two-Step Resume Information Extraction Algorithm

    Directory of Open Access Journals (Sweden)

    Jie Chen

    2018-01-01

    Full Text Available With the rapid growth of Internet-based recruiting, there are a great number of personal resumes among recruiting systems. To gain more attention from the recruiters, most resumes are written in diverse formats, including varying font size, font colour, and table cells. However, the diversity of format is harmful to data mining, such as resume information extraction, automatic job matching, and candidates ranking. Supervised methods and rule-based methods have been proposed to extract facts from resumes, but they strongly rely on hierarchical structure information and large amounts of labelled data, which are hard to collect in reality. In this paper, we propose a two-step resume information extraction approach. In the first step, raw text of resume is identified as different resume blocks. To achieve the goal, we design a novel feature, Writing Style, to model sentence syntax information. Besides word index and punctuation index, word lexical attribute and prediction results of classifiers are included in Writing Style. In the second step, multiple classifiers are employed to identify different attributes of fact information in resumes. Experimental results on a real-world dataset show that the algorithm is feasible and effective.

  11. Structural hybrid reliability index and its convergent solving method based on random–fuzzy–interval reliability model

    Directory of Open Access Journals (Sweden)

    Hai An

    2016-08-01

    Full Text Available Aiming to resolve the problems of a variety of uncertainty variables that coexist in the engineering structure reliability analysis, a new hybrid reliability index to evaluate structural hybrid reliability, based on the random–fuzzy–interval model, is proposed in this article. The convergent solving method is also presented. First, the truncated probability reliability model, the fuzzy random reliability model, and the non-probabilistic interval reliability model are introduced. Then, the new hybrid reliability index definition is presented based on the random–fuzzy–interval model. Furthermore, the calculation flowchart of the hybrid reliability index is presented and it is solved using the modified limit-step length iterative algorithm, which ensures convergence. And the validity of convergent algorithm for the hybrid reliability model is verified through the calculation examples in literature. In the end, a numerical example is demonstrated to show that the hybrid reliability index is applicable for the wear reliability assessment of mechanisms, where truncated random variables, fuzzy random variables, and interval variables coexist. The demonstration also shows the good convergence of the iterative algorithm proposed in this article.

  12. Strong Stability Preserving Explicit Linear Multistep Methods with Variable Step Size

    KAUST Repository

    Hadjimichael, Yiannis; Ketcheson, David I.; Loczi, Lajos; Né meth, Adriá n

    2016-01-01

    Strong stability preserving (SSP) methods are designed primarily for time integration of nonlinear hyperbolic PDEs, for which the permissible SSP step size varies from one step to the next. We develop the first SSP linear multistep methods (of order

  13. The lead-lag relationship between stock index and stock index futures: A thermal optimal path method

    Science.gov (United States)

    Gong, Chen-Chen; Ji, Shen-Dan; Su, Li-Ling; Li, Sai-Ping; Ren, Fei

    2016-02-01

    The study of lead-lag relationship between stock index and stock index futures is of great importance for its wide application in hedging and portfolio investments. Previous works mainly use conventional methods like Granger causality test, GARCH model and error correction model, and focus on the causality relation between the index and futures in a certain period. By using a non-parametric approach-thermal optimal path (TOP) method, we study the lead-lag relationship between China Securities Index 300 (CSI 300), Hang Seng Index (HSI), Standard and Poor 500 (S&P 500) Index and their associated futures to reveal the variance of their relationship over time. Our finding shows evidence of pronounced futures leadership for well established index futures, namely HSI and S&P 500 index futures, while index of developing market like CSI 300 has pronounced leadership. We offer an explanation based on the measure of an indicator which quantifies the differences between spot and futures prices for the surge of lead-lag function. Our results provide new perspectives for the understanding of the dynamical evolution of lead-lag relationship between stock index and stock index futures, which is valuable for the study of market efficiency and its applications.

  14. The grazing index method of range condition assessment | du Toit ...

    African Journals Online (AJOL)

    Owing to the difficulty of examining succession theory in the Karoo, it is suggested the ecological index method (EIM), be replaced by the grazing index method (GIM), through the introduction of grazing index values (GIV) for Karoo plant species. The GIM may provide more acceptable range condition scores and more ...

  15. Perturbed Strong Stability Preserving Time-Stepping Methods For Hyperbolic PDEs

    KAUST Repository

    Hadjimichael, Yiannis

    2017-09-30

    A plethora of physical phenomena are modelled by hyperbolic partial differential equations, for which the exact solution is usually not known. Numerical methods are employed to approximate the solution to hyperbolic problems; however, in many cases it is difficult to satisfy certain physical properties while maintaining high order of accuracy. In this thesis, we develop high-order time-stepping methods that are capable of maintaining stability constraints of the solution, when coupled with suitable spatial discretizations. Such methods are called strong stability preserving (SSP) time integrators, and we mainly focus on perturbed methods that use both upwind- and downwind-biased spatial discretizations. Firstly, we introduce a new family of third-order implicit Runge–Kuttas methods with arbitrarily large SSP coefficient. We investigate the stability and accuracy of these methods and we show that they perform well on hyperbolic problems with large CFL numbers. Moreover, we extend the analysis of SSP linear multistep methods to semi-discretized problems for which different terms on the right-hand side of the initial value problem satisfy different forward Euler (or circle) conditions. Optimal perturbed and additive monotonicity-preserving linear multistep methods are studied in the context of such problems. Optimal perturbed methods attain augmented monotonicity-preserving step sizes when the different forward Euler conditions are taken into account. On the other hand, we show that optimal SSP additive methods achieve a monotonicity-preserving step-size restriction no better than that of the corresponding non-additive SSP linear multistep methods. Furthermore, we develop the first SSP linear multistep methods of order two and three with variable step size, and study their optimality. We describe an optimal step-size strategy and demonstrate the effectiveness of these methods on various one- and multi-dimensional problems. Finally, we establish necessary conditions

  16. MIDPOINT TWO- STEPS RULE FOR THE SQUARE ROOT METHOD

    African Journals Online (AJOL)

    DR S.E UWAMUSI

    Aberth third order method for finding zeros of a polynomial in interval ... KEY WORDS: Square root iteration, midpoint two steps Method, ...... A New set of Methods for the simultaneous determination of zeros of polynomial equation and iterative ...

  17. From the Index Numers’ Method to the Method Of Coefficient Of Elasticity

    Directory of Open Access Journals (Sweden)

    Gheorghe Săvoiu

    2013-08-01

    Full Text Available Using the simple method of index numbers, and synthesizing the originality of his excellent statistical thinking by definition, this article identifies and presents an inimitable shortcut from Index – Numbers’ method to elasticity method. A final remark underlines the beauty and the rigour of this scientific demarche specific for the statistical thinking. This paper is a real homage addressed to Professor M. C. Demetrescu, and to his remarkable PhD thesis, printed approximately half a century ago, one of the best statistic and economic book about population demand.

  18. Considerations for the independent reaction times and step-by-step methods for radiation chemistry simulations

    Science.gov (United States)

    Plante, Ianik; Devroye, Luc

    2017-10-01

    Ionizing radiation interacts with the water molecules of the tissues mostly by ionizations and excitations, which result in the formation of the radiation track structure and the creation of radiolytic species such as H.,.OH, H2, H2O2, and e-aq. After their creation, these species diffuse and may chemically react with the neighboring species and with the molecules of the medium. Therefore radiation chemistry is of great importance in radiation biology. As the chemical species are not distributed homogeneously, the use of conventional models of homogeneous reactions cannot completely describe the reaction kinetics of the particles. Actually, many simulations of radiation chemistry are done using the Independent Reaction Time (IRT) method, which is a very fast technique to calculate radiochemical yields but which do not calculate the positions of the radiolytic species as a function of time. Step-by-step (SBS) methods, which are able to provide such information, have been used only sparsely because these are time-consuming in terms of calculation. Recent improvements in computer performance now allow the regular use of the SBS method in radiation chemistry. The SBS and IRT methods are both based on the Green's functions of the diffusion equation (GFDE). In this paper, several sampling algorithms of the GFDE and for the IRT method are presented. We show that the IRT and SBS methods are exactly equivalent for 2-particles systems for diffusion and partially diffusion-controlled reactions between non-interacting particles. We also show that the results obtained with the SBS simulation method with periodic boundary conditions are in agreement with the predictions by classical reaction kinetics theory, which is an important step towards using this method for modelling of biochemical networks and metabolic pathways involved in oxidative stress. Finally, the first simulation results obtained with the code RITRACKS (Relativistic Ion Tracks) are presented.

  19. An exact method for computing the frustration index in signed networks using binary programming

    OpenAIRE

    Aref, Samin; Mason, Andrew J.; Wilson, Mark C.

    2016-01-01

    Computing the frustration index of a signed graph is a key step toward solving problems in many fields including social networks, physics, material science, and biology. The frustration index determines the distance of a network from a state of total structural balance. Although the definition of the frustration index goes back to 1960, its exact algorithmic computation, which is closely related to classic NP-hard graph problems, has only become a focus in recent years. We develop three new b...

  20. The Fractional Step Method Applied to Simulations of Natural Convective Flows

    Science.gov (United States)

    Westra, Douglas G.; Heinrich, Juan C.; Saxon, Jeff (Technical Monitor)

    2002-01-01

    This paper describes research done to apply the Fractional Step Method to finite-element simulations of natural convective flows in pure liquids, permeable media, and in a directionally solidified metal alloy casting. The Fractional Step Method has been applied commonly to high Reynold's number flow simulations, but is less common for low Reynold's number flows, such as natural convection in liquids and in permeable media. The Fractional Step Method offers increased speed and reduced memory requirements by allowing non-coupled solution of the pressure and the velocity components. The Fractional Step Method has particular benefits for predicting flows in a directionally solidified alloy, since other methods presently employed are not very efficient. Previously, the most suitable method for predicting flows in a directionally solidified binary alloy was the penalty method. The penalty method requires direct matrix solvers, due to the penalty term. The Fractional Step Method allows iterative solution of the finite element stiffness matrices, thereby allowing more efficient solution of the matrices. The Fractional Step Method also lends itself to parallel processing, since the velocity component stiffness matrices can be built and solved independently of each other. The finite-element simulations of a directionally solidified casting are used to predict macrosegregation in directionally solidified castings. In particular, the finite-element simulations predict the existence of 'channels' within the processing mushy zone and subsequently 'freckles' within the fully processed solid, which are known to result from macrosegregation, or what is often referred to as thermo-solutal convection. These freckles cause material property non-uniformities in directionally solidified castings; therefore many of these castings are scrapped. The phenomenon of natural convection in an alloy under-going directional solidification, or thermo-solutal convection, will be explained. The

  1. A Spiral Step-by-Step Educational Method for Cultivating Competent Embedded System Engineers to Meet Industry Demands

    Science.gov (United States)

    Jing,Lei; Cheng, Zixue; Wang, Junbo; Zhou, Yinghui

    2011-01-01

    Embedded system technologies are undergoing dramatic change. Competent embedded system engineers are becoming a scarce resource in the industry. Given this, universities should revise their specialist education to meet industry demands. In this paper, a spirally tight-coupled step-by-step educational method, based on an analysis of industry…

  2. Step index fibre using laser interferometer

    Indian Academy of Sciences (India)

    2014-03-04

    Mar 4, 2014 ... We propose the following model to describe the cladded fibre placed inside a liquid wedge interferometer. For simplicity, we assume square interferometer plates of dimensions 2a,. 2b and refractive index μL. The fibre radius is rf and the core radius is rc with skin and core indices μs, μc respectively. Hence ...

  3. Generation of infrared supercontinuum radiation: spatial mode dispersion and higher-order mode propagation in ZBLAN step-index fibers

    DEFF Research Database (Denmark)

    Ramsay, Jacob Søndergaard; Dupont, Sune Vestergaard Lund; Johansen, Mikkel Willum

    2013-01-01

    Using femtosecond upconversion we investigate the time and wavelength structure of infrared supercontinuum generation. It is shown that radiation is scattered into higher order spatial modes (HOMs) when generating a supercontinuum using fibers that are not single-moded, such as a step-index ZBLAN...... not include scattering into HOMs, and including this provides an extra degree of freedom for tailoring supercontinuum sources....

  4. The Technique of Changing the Drive Method of Micro Step Drive and Sensorless Drive for Hybrid Stepping Motor

    Science.gov (United States)

    Yoneda, Makoto; Dohmeki, Hideo

    The position control system with the advantage large torque, low vibration, and high resolution can be obtained by the constant current micro step drive applied to hybrid stepping motor. However loss is large, in order not to be concerned with load torque but to control current uniformly. As the one technique of a position control system in which high efficiency is realizable, the same sensorless control as a permanent magnet motor is effective. But, it was the purpose that the control method proposed until now controls speed. Then, this paper proposed changing the drive method of micro step drive and sensorless drive. The change of the drive method was verified from the simulation and the experiment. On no load, it was checked not producing change of a large speed at the time of a change by making electrical angle and carrying out zero reset of the integrator. On load, it was checked that a large speed change arose. The proposed system could change drive method by setting up the initial value of an integrator using the estimated result, without producing speed change. With this technique, the low loss position control system, which employed the advantage of the hybrid stepping motor, has been built.

  5. Improved Full-Newton Step O(nL) Infeasible Interior-Point Method for Linear Optimization

    NARCIS (Netherlands)

    Gu, G.; Mansouri, H.; Zangiabadi, M.; Bai, Y.Q.; Roos, C.

    2009-01-01

    We present several improvements of the full-Newton step infeasible interior-point method for linear optimization introduced by Roos (SIAM J. Optim. 16(4):1110–1136, 2006). Each main step of the method consists of a feasibility step and several centering steps. We use a more natural feasibility step,

  6. Comparing Multi-Step IMAC and Multi-Step TiO2 Methods for Phosphopeptide Enrichment

    Science.gov (United States)

    Yue, Xiaoshan; Schunter, Alissa; Hummon, Amanda B.

    2016-01-01

    Phosphopeptide enrichment from complicated peptide mixtures is an essential step for mass spectrometry-based phosphoproteomic studies to reduce sample complexity and ionization suppression effects. Typical methods for enriching phosphopeptides include immobilized metal affinity chromatography (IMAC) or titanium dioxide (TiO2) beads, which have selective affinity and can interact with phosphopeptides. In this study, the IMAC enrichment method was compared with the TiO2 enrichment method, using a multi-step enrichment strategy from whole cell lysate, to evaluate their abilities to enrich for different types of phosphopeptides. The peptide-to-beads ratios were optimized for both IMAC and TiO2 beads. Both IMAC and TiO2 enrichments were performed for three rounds to enable the maximum extraction of phosphopeptides from the whole cell lysates. The phosphopeptides that are unique to IMAC enrichment, unique to TiO2 enrichment, and identified with both IMAC and TiO2 enrichment were analyzed for their characteristics. Both IMAC and TiO2 enriched similar amounts of phosphopeptides with comparable enrichment efficiency. However, phosphopeptides that are unique to IMAC enrichment showed a higher percentage of multi-phosphopeptides, as well as a higher percentage of longer, basic, and hydrophilic phosphopeptides. Also, the IMAC and TiO2 procedures clearly enriched phosphopeptides with different motifs. Finally, further enriching with two rounds of TiO2 from the supernatant after IMAC enrichment, or further enriching with two rounds of IMAC from the supernatant TiO2 enrichment does not fully recover the phosphopeptides that are not identified with the corresponding multi-step enrichment. PMID:26237447

  7. Combined Effects of Numerical Method Type and Time Step on Water Stressed Actual Crop ET

    Directory of Open Access Journals (Sweden)

    B. Ghahraman

    2016-02-01

    Full Text Available Introduction: Actual crop evapotranspiration (Eta is important in hydrologic modeling and irrigation water management issues. Actual ET depends on an estimation of a water stress index and average soil water at crop root zone, and so depends on a chosen numerical method and adapted time step. During periods with no rainfall and/or irrigation, actual ET can be computed analytically or by using different numerical methods. Overal, there are many factors that influence actual evapotranspiration. These factors are crop potential evapotranspiration, available root zone water content, time step, crop sensitivity, and soil. In this paper different numerical methods are compared for different soil textures and different crops sensitivities. Materials and Methods: During a specific time step with no rainfall or irrigation, change in soil water content would be equal to evapotranspiration, ET. In this approach, however, deep percolation is generally ignored due to deep water table and negligible unsaturated hydraulic conductivity below rooting depth. This differential equation may be solved analytically or numerically considering different algorithms. We adapted four different numerical methods, as explicit, implicit, and modified Euler, midpoint method, and 3-rd order Heun method to approximate the differential equation. Three general soil types of sand, silt, and clay, and three different crop types of sensitive, moderate, and resistant under Nishaboor plain were used. Standard soil fraction depletion (corresponding to ETc=5 mm.d-1, pstd, below which crop faces water stress is adopted for crop sensitivity. Three values for pstd were considered in this study to cover the common crops in the area, including winter wheat and barley, cotton, alfalfa, sugar beet, saffron, among the others. Based on this parameter, three classes for crop sensitivity was considered, sensitive crops with pstd=0.2, moderate crops with pstd=0.5, and resistive crops with pstd=0

  8. A two-step Hilbert transform method for 2D image reconstruction

    International Nuclear Information System (INIS)

    Noo, Frederic; Clackdoyle, Rolf; Pack, Jed D

    2004-01-01

    The paper describes a new accurate two-dimensional (2D) image reconstruction method consisting of two steps. In the first step, the backprojected image is formed after taking the derivative of the parallel projection data. In the second step, a Hilbert filtering is applied along certain lines in the differentiated backprojection (DBP) image. Formulae for performing the DBP step in fan-beam geometry are also presented. The advantage of this two-step Hilbert transform approach is that in certain situations, regions of interest (ROIs) can be reconstructed from truncated projection data. Simulation results are presented that illustrate very similar reconstructed image quality using the new method compared to standard filtered backprojection, and that show the capability to correctly handle truncated projections. In particular, a simulation is presented of a wide patient whose projections are truncated laterally yet for which highly accurate ROI reconstruction is obtained

  9. Stability of one-step methods in transient nonlinear heat conduction

    International Nuclear Information System (INIS)

    Hughes, J.R.

    1977-01-01

    The purpose of the present work is to ascertain practical stability conditions for one-step methods commonly used in transient nonlinear heat conduction analyses. The class of problems considered is governed by a temporally continuous, spatially discrete system involving the capacity matrix C, conductivity matrix K, heat supply vector, temperature vector and time differenciation. In the linear case, in which K and C are constant, the stability behavior of one-step methods is well known. But in this paper the concepts of stability, appropriate to the nonlinear problem, are thoroughly discussed. They of course reduce to the usual stability criterion for the linear, constant coefficient case. However, for nonlinear problems there are differences and these ideas are of key importance in obtaining practical stability conditions. Of particular importance is a recent result which indicates that, in a sense, the trapezoidal and midpoint families are quivalent. Thus, stability results for one family may be translated into a result for the other. The main results obtained are summarized as follows. The stability behavior of the explicit Euler method in the nonlinear regime is analogous to that for linear problems. In particular, an a priori step size restriction may be determined for each time step. The precise time step restriction on implicit conditionally stable members of the trapezoidal and midpoint families is shown not to be determinable a priori. Of considerable practical significance, unconditionally stable members of the trapezoidal and midpoint families are identified

  10. Determining the group velocity dispersion by field analysis for the LP0X, LP1X, and LP2X mode groups independently of the fiber length: applications to step-index fibers

    DEFF Research Database (Denmark)

    Israelsen, Stine Møller; Usuga Castaneda, Mario A.; Rottwitt, Karsten

    2017-01-01

    By knowing the electric field distribution of a guided mode in an optical fiber, we are able to evaluate the group velocity dispersion in a weakly guiding step-index fiber for a pure mode in the LP0X, LP1X, and LP2X mode groups independently of the fiber length. We demonstrate the method numerica...

  11. Comparison of the Screening Tests for Gestational Diabetes Mellitus between "One-Step" and "Two-Step" Methods among Thai Pregnant Women.

    Science.gov (United States)

    Luewan, Suchaya; Bootchaingam, Phenphan; Tongsong, Theera

    2018-01-01

    To compare the prevalence and pregnancy outcomes of GDM between those screened by the "one-step" (75 gm GTT) and "two-step" (100 gm GTT) methods. A prospective study was conducted on singleton pregnancies at low or average risk of GDM. All were screened between 24 and 28 weeks, using the one-step or two-step method based on patients' preference. The primary outcome was prevalence of GDM, and secondary outcomes included birthweight, gestational age, rates of preterm birth, small/large-for-gestational age, low Apgar scores, cesarean section, and pregnancy-induced hypertension. A total of 648 women were screened: 278 in the one-step group and 370 in the two-step group. The prevalence of GDM was significantly higher in the one-step group; 32.0% versus 10.3%. Baseline characteristics and pregnancy outcomes in both groups were comparable. However, mean birthweight was significantly higher among pregnancies with GDM diagnosed by the two-step approach (3204 ± 555 versus 3009 ± 666 g; p =0.022). Likewise, the rate of large-for-date tended to be higher in the two-step group, but was not significant. The one-step approach is associated with very high prevalence of GDM among Thai population, without clear evidence of better outcomes. Thus, this approach may not be appropriate for screening in a busy antenatal care clinic like our setting or other centers in developing countries.

  12. Improved Full-Newton Step O(nL) Infeasible Interior-Point Method for Linear Optimization

    OpenAIRE

    Gu, G.; Mansouri, H.; Zangiabadi, M.; Bai, Y.Q.; Roos, C.

    2009-01-01

    We present several improvements of the full-Newton step infeasible interior-point method for linear optimization introduced by Roos (SIAM J. Optim. 16(4):1110–1136, 2006). Each main step of the method consists of a feasibility step and several centering steps. We use a more natural feasibility step, which targets the ?+-center of the next pair of perturbed problems. As for the centering steps, we apply a sharper quadratic convergence result, which leads to a slightly wider neighborhood for th...

  13. Refractive index inversion based on Mueller matrix method

    Science.gov (United States)

    Fan, Huaxi; Wu, Wenyuan; Huang, Yanhua; Li, Zhaozhao

    2016-03-01

    Based on Stokes vector and Jones vector, the correlation between Mueller matrix elements and refractive index was studied with the result simplified, and through Mueller matrix way, the expression of refractive index inversion was deduced. The Mueller matrix elements, under different incident angle, are simulated through the expression of specular reflection so as to analyze the influence of the angle of incidence and refractive index on it, which is verified through the measure of the Mueller matrix elements of polished metal surface. Research shows that, under the condition of specular reflection, the result of Mueller matrix inversion is consistent with the experiment and can be used as an index of refraction of inversion method, and it provides a new way for target detection and recognition technology.

  14. SPAR-H Step-by-Step Guidance

    Energy Technology Data Exchange (ETDEWEB)

    W. J. Galyean; A. M. Whaley; D. L. Kelly; R. L. Boring

    2011-05-01

    This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from the psychology literature.

  15. SPAR-H Step-by-Step Guidance

    International Nuclear Information System (INIS)

    Galyean, W.J.; Whaley, A.M.; Kelly, D.L.; Boring, R.L.

    2011-01-01

    This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from the psychology literature.

  16. Q-Step methods for Newton-Jacobi operator equation | Uwasmusi ...

    African Journals Online (AJOL)

    The paper considers the Newton-Jacobi operator equation for the solution of nonlinear systems of equations. Special attention is paid to the computational part of this method with particular reference to the q-step methods. Journal of the Nigerian Association of Mathematical Physics Vol. 8 2004: pp. 237-241 ...

  17. some generalized two-step block hybrid numerov method for solving ...

    African Journals Online (AJOL)

    Nwokem et al.

    ABSTRACT. This paper proposes a class of generalized two-step Numerov methods, a block hybrid type for the direct solution of general second order ordinary differential equations. Both the main method and additional methods were derived via interpolation and collocation procedures. The basic properties of zero ...

  18. An efficient modularized sample-based method to estimate the first-order Sobol' index

    International Nuclear Information System (INIS)

    Li, Chenzhao; Mahadevan, Sankaran

    2016-01-01

    Sobol' index is a prominent methodology in global sensitivity analysis. This paper aims to directly estimate the Sobol' index based only on available input–output samples, even if the underlying model is unavailable. For this purpose, a new method to calculate the first-order Sobol' index is proposed. The innovation is that the conditional variance and mean in the formula of the first-order index are calculated at an unknown but existing location of model inputs, instead of an explicit user-defined location. The proposed method is modularized in two aspects: 1) index calculations for different model inputs are separate and use the same set of samples; and 2) model input sampling, model evaluation, and index calculation are separate. Due to this modularization, the proposed method is capable to compute the first-order index if only input–output samples are available but the underlying model is unavailable, and its computational cost is not proportional to the dimension of the model inputs. In addition, the proposed method can also estimate the first-order index with correlated model inputs. Considering that the first-order index is a desired metric to rank model inputs but current methods can only handle independent model inputs, the proposed method contributes to fill this gap. - Highlights: • An efficient method to estimate the first-order Sobol' index. • Estimate the index from input–output samples directly. • Computational cost is not proportional to the number of model inputs. • Handle both uncorrelated and correlated model inputs.

  19. A Normalized Transfer Matrix Method for the Free Vibration of Stepped Beams: Comparison with Experimental and FE(3D Methods

    Directory of Open Access Journals (Sweden)

    Tamer Ahmed El-Sayed

    2017-01-01

    Full Text Available The exact solution for multistepped Timoshenko beam is derived using a set of fundamental solutions. This set of solutions is derived to normalize the solution at the origin of the coordinates. The start, end, and intermediate boundary conditions involve concentrated masses and linear and rotational elastic supports. The beam start, end, and intermediate equations are assembled using the present normalized transfer matrix (NTM. The advantage of this method is that it is quicker than the standard method because the size of the complete system coefficient matrix is 4 × 4. In addition, during the assembly of this matrix, there are no inverse matrix steps required. The validity of this method is tested by comparing the results of the current method with the literature. Then the validity of the exact stepped analysis is checked using experimental and FE(3D methods. The experimental results for stepped beams with single step and two steps, for sixteen different test samples, are in excellent agreement with those of the three-dimensional finite element FE(3D. The comparison between the NTM method and the finite element method results shows that the modal percentage deviation is increased when a beam step location coincides with a peak point in the mode shape. Meanwhile, the deviation decreases when a beam step location coincides with a straight portion in the mode shape.

  20. Multi-Index Monte Carlo and stochastic collocation methods for random PDEs

    KAUST Repository

    Nobile, Fabio; Haji Ali, Abdul Lateef; Tamellini, Lorenzo; Tempone, Raul

    2016-01-01

    In this talk we consider the problem of computing statistics of the solution of a partial differential equation with random data, where the random coefficient is parametrized by means of a finite or countable sequence of terms in a suitable expansion. We describe and analyze a Multi-Index Monte Carlo (MIMC) and a Multi-Index Stochastic Collocation method (MISC). the former is both a stochastic version of the combination technique introduced by Zenger, Griebel and collaborators and an extension of the Multilevel Monte Carlo (MLMC) method first described by Heinrich and Giles. Instead of using firstorder differences as in MLMC, MIMC uses mixed differences to reduce the variance of the hierarchical differences dramatically. This in turn yields new and improved complexity results, which are natural generalizations of Giles s MLMC analysis, and which increase the domain of problem parameters for which we achieve the optimal convergence, O(TOL-2). On the same vein, MISC is a deterministic combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. Provided enough mixed regularity, MISC can achieve better complexity than MIMC. Moreover, we show that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one-dimensional spatial problem. We propose optimization procedures to select the most effective mixed differences to include in MIMC and MISC. Such optimization is a crucial step that allows us to make MIMC and MISC computationally effective. We finally show the effectiveness of MIMC and MISC with some computational tests, including tests with a infinite countable number of random parameters.

  1. Multi-Index Monte Carlo and stochastic collocation methods for random PDEs

    KAUST Repository

    Nobile, Fabio

    2016-01-09

    In this talk we consider the problem of computing statistics of the solution of a partial differential equation with random data, where the random coefficient is parametrized by means of a finite or countable sequence of terms in a suitable expansion. We describe and analyze a Multi-Index Monte Carlo (MIMC) and a Multi-Index Stochastic Collocation method (MISC). the former is both a stochastic version of the combination technique introduced by Zenger, Griebel and collaborators and an extension of the Multilevel Monte Carlo (MLMC) method first described by Heinrich and Giles. Instead of using firstorder differences as in MLMC, MIMC uses mixed differences to reduce the variance of the hierarchical differences dramatically. This in turn yields new and improved complexity results, which are natural generalizations of Giles s MLMC analysis, and which increase the domain of problem parameters for which we achieve the optimal convergence, O(TOL-2). On the same vein, MISC is a deterministic combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. Provided enough mixed regularity, MISC can achieve better complexity than MIMC. Moreover, we show that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one-dimensional spatial problem. We propose optimization procedures to select the most effective mixed differences to include in MIMC and MISC. Such optimization is a crucial step that allows us to make MIMC and MISC computationally effective. We finally show the effectiveness of MIMC and MISC with some computational tests, including tests with a infinite countable number of random parameters.

  2. Single-phase Near-well Permeability Upscaling and Productivity Index Calculation Methods

    Directory of Open Access Journals (Sweden)

    Seyed Shamsollah Noorbakhsh

    2014-10-01

    Full Text Available Reservoir models with many grid blocks suffer from long run time; it is hence important to deliberate a method to remedy this drawback. Usual upscaling methods are proved to fail to reproduce fine grid model behaviors in coarse grid models in well proximity. This is attributed to rapid pressure changes in the near-well region. Standard permeability upscaling methods are limited to systems with linear pressure changes; therefore, special near-well upscaling approaches based on the well index concept are proposed for these regions with non-linear pressure profile. No general rule is available to calculate the proper well index in different heterogeneity patterns and coarsening levels. In this paper, the available near-well upscaling methods are investigated for homogeneous and heterogeneous permeability models at different coarsening levels. It is observed that the existing well index methods have limited success in reproducing the well flow and pressure behavior of the reference fine grid models as the heterogeneity or coarsening level increases. Coarse-scale well indexes are determined such that fine and coarse scale results for pressure are in agreement. Both vertical and horizontal wells are investigated and, for the case of vertical homogeneous wells, a linear relationship between the default (Peaceman well index and the true (matched well index is obtained, which considerably reduces the error of the Peaceman well index. For the case of heterogeneous vertical wells, a multiplier remedies the error. Similar results are obtained for horizontal wells (both heterogeneous and homogeneous models.

  3. Multiple-time-stepping generalized hybrid Monte Carlo methods

    Energy Technology Data Exchange (ETDEWEB)

    Escribano, Bruno, E-mail: bescribano@bcamath.org [BCAM—Basque Center for Applied Mathematics, E-48009 Bilbao (Spain); Akhmatskaya, Elena [BCAM—Basque Center for Applied Mathematics, E-48009 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science, E-48013 Bilbao (Spain); Reich, Sebastian [Universität Potsdam, Institut für Mathematik, D-14469 Potsdam (Germany); Azpiroz, Jon M. [Kimika Fakultatea, Euskal Herriko Unibertsitatea (UPV/EHU) and Donostia International Physics Center (DIPC), P.K. 1072, Donostia (Spain)

    2015-01-01

    Performance of the generalized shadow hybrid Monte Carlo (GSHMC) method [1], which proved to be superior in sampling efficiency over its predecessors [2–4], molecular dynamics and hybrid Monte Carlo, can be further improved by combining it with multi-time-stepping (MTS) and mollification of slow forces. We demonstrate that the comparatively simple modifications of the method not only lead to better performance of GSHMC itself but also allow for beating the best performed methods, which use the similar force splitting schemes. In addition we show that the same ideas can be successfully applied to the conventional generalized hybrid Monte Carlo method (GHMC). The resulting methods, MTS-GHMC and MTS-GSHMC, provide accurate reproduction of thermodynamic and dynamical properties, exact temperature control during simulation and computational robustness and efficiency. MTS-GHMC uses a generalized momentum update to achieve weak stochastic stabilization to the molecular dynamics (MD) integrator. MTS-GSHMC adds the use of a shadow (modified) Hamiltonian to filter the MD trajectories in the HMC scheme. We introduce a new shadow Hamiltonian formulation adapted to force-splitting methods. The use of such Hamiltonians improves the acceptance rate of trajectories and has a strong impact on the sampling efficiency of the method. Both methods were implemented in the open-source MD package ProtoMol and were tested on a water and a protein systems. Results were compared to those obtained using a Langevin Molly (LM) method [5] on the same systems. The test results demonstrate the superiority of the new methods over LM in terms of stability, accuracy and sampling efficiency. This suggests that putting the MTS approach in the framework of hybrid Monte Carlo and using the natural stochasticity offered by the generalized hybrid Monte Carlo lead to improving stability of MTS and allow for achieving larger step sizes in the simulation of complex systems.

  4. Microsoft Office Word 2007 step by step

    CERN Document Server

    Cox, Joyce

    2007-01-01

    Experience learning made easy-and quickly teach yourself how to create impressive documents with Word 2007. With Step By Step, you set the pace-building and practicing the skills you need, just when you need them!Apply styles and themes to your document for a polished lookAdd graphics and text effects-and see a live previewOrganize information with new SmartArt diagrams and chartsInsert references, footnotes, indexes, a table of contentsSend documents for review and manage revisionsTurn your ideas into blogs, Web pages, and moreYour all-in-one learning experience includes:Files for building sk

  5. Using a Three-Step Method in a Calculus Class: Extending the Worked Example

    Science.gov (United States)

    Miller, David

    2010-01-01

    This article discusses a three-step method that was used in a college calculus course. The three-step method was developed to help students understand the course material and transition to be more independent learners. In addition, the method helped students to transfer concepts from short-term to long-term memory while lowering cognitive load.…

  6. Comparison of 10 single and stepped methods to identify frail older persons in primary care: diagnostic and prognostic accuracy.

    Science.gov (United States)

    Sutorius, Fleur L; Hoogendijk, Emiel O; Prins, Bernard A H; van Hout, Hein P J

    2016-08-03

    Many instruments have been developed to identify frail older adults in primary care. A direct comparison of the accuracy and prevalence of identification methods is rare and most studies ignore the stepped selection typically employed in routine care practice. Also it is unclear whether the various methods select persons with different characteristics. We aimed to estimate the accuracy of 10 single and stepped methods to identify frailty in older adults and to predict adverse health outcomes. In addition, the methods were compared on their prevalence of the identified frail persons and on the characteristics of persons identified. The Groningen Frailty Indicator (GFI), the PRISMA-7, polypharmacy, the clinical judgment of the general practitioner (GP), the self-rated health of the older adult, the Edmonton Frail Scale (EFS), the Identification Seniors At Risk Primary Care (ISAR PC), the Frailty Index (FI), the InterRAI screener and gait speed were compared to three measures: two reference standards (the clinical judgment of a multidisciplinary expert panel and Fried's frailty criteria) and 6-years mortality or long term care admission. Data were used from the Dutch Identification of Frail Elderly Study, consisting of 102 people aged 65 and over from a primary care practice in Amsterdam. Frail older adults were oversampled. The accuracy of each instrument and several stepped strategies was estimated by calculating the area under the ROC-curve. Prevalence rates of frailty ranged from 14.8 to 52.9 %. The accuracy for recommended cut off values ranged from poor (AUC = 0.556 ISAR-PC) to good (AUC = 0.865 gait speed). PRISMA-7 performed best over two reference standards, GP predicted adversities best. Stepped strategies resulted in lower prevalence rates and accuracy. Persons selected by the different instruments varied greatly in age, IADL dependency, receiving homecare and mood. We found huge differences between methods to identify frail persons in prevalence

  7. Stability of one-step methods in transient nonlinear heat conduction

    International Nuclear Information System (INIS)

    Hughes, J.R.

    1977-01-01

    The purpose of the present work is to ascertain practical stability conditions for one-step methods commonly used in transient nonlinear heat conduction analyses. In this paper the concepts of stability, appropriate to the nonlinear problem, are thoroughly discussed. They of course reduce to the usual stability critierion for the linear, constant coefficient case. However, for nonlinear problems there are differences and theses ideas are of key importance in obtaining practical stability conditions. Of particular importance is a recent result which indicates that, in a sense, the trapezoidal and midpoint families are equivalent. Thus, stability results for one family may be translated into a result for the other. The main results obtained are: The stability behaviour of the explicit Euler method in the nonlinear regime is analogous to that for linear problems. In particular, an a priori step size restriction may be determined for each time step. The precise time step restriction on implicit conditionally stable members of the trapezoidal and midpoint families is shown not to be determinable a priori. Of considerable practical significance, unconditionally stable members of the trapezoidal and midpoint families are identified. All notions of stability employed are motivated and defined, and their interpretations in practical computing are indicated. (Auth.)

  8. Detection of protein concentrations using a pH-step titration method

    NARCIS (Netherlands)

    Kruise, J.; Kruise, J.; Eijkel, Jan C.T.; Bergveld, Piet

    1997-01-01

    A stimulus-response method based on the application of a pH step is proposed for the detection of protein immobilized in a membrane on top of an ion-sensitive field-effect transistor (ISFET). The ISFET response to a step-wise change in pH, applied at the interface between the membrane and the

  9. Monte Carlo method for polarized radiative transfer in gradient-index media

    International Nuclear Information System (INIS)

    Zhao, J.M.; Tan, J.Y.; Liu, L.H.

    2015-01-01

    Light transfer in gradient-index media generally follows curved ray trajectories, which will cause light beam to converge or diverge during transfer and induce the rotation of polarization ellipse even when the medium is transparent. Furthermore, the combined process of scattering and transfer along curved ray path makes the problem more complex. In this paper, a Monte Carlo method is presented to simulate polarized radiative transfer in gradient-index media that only support planar ray trajectories. The ray equation is solved to the second order to address the effect induced by curved ray trajectories. Three types of test cases are presented to verify the performance of the method, which include transparent medium, Mie scattering medium with assumed gradient index distribution, and Rayleigh scattering with realistic atmosphere refractive index profile. It is demonstrated that the atmospheric refraction has significant effect for long distance polarized light transfer. - Highlights: • A Monte Carlo method for polarized radiative transfer in gradient index media. • Effect of curved ray paths on polarized radiative transfer is considered. • Importance of atmospheric refraction for polarized light transfer is demonstrated

  10. Indexation automatique des textes arabes : état de l’art

    Directory of Open Access Journals (Sweden)

    Mohamed Salim El Bazzi

    2016-11-01

    Full Text Available Document indexing is a crucial step in the text mining process. It is used to represent documents by the most relevant descriptors of their contents. Several approaches are proposed in the literature, particularly for English, but they are unusable for Arabic documents, considering its specific characteristics and its morphological complexity, grammar and vocabulary. In this paper, we present a reading in the state of the art of indexation methods and their contribution to improve Arabic document’s processing. We also propose a categorization of works according to the most used approaches and methods for indexing textual documents. We adopted a qualitative selection of papers and we retained papers approving notable indexation contributions and illustrating significant results

  11. Method for selection of optimal road safety composite index with examples from DEA and TOPSIS method.

    Science.gov (United States)

    Rosić, Miroslav; Pešić, Dalibor; Kukić, Dragoslav; Antić, Boris; Božović, Milan

    2017-01-01

    Concept of composite road safety index is a popular and relatively new concept among road safety experts around the world. As there is a constant need for comparison among different units (countries, municipalities, roads, etc.) there is need to choose an adequate method which will make comparison fair to all compared units. Usually comparisons using one specific indicator (parameter which describes safety or unsafety) can end up with totally different ranking of compared units which is quite complicated for decision maker to determine "real best performers". Need for composite road safety index is becoming dominant since road safety presents a complex system where more and more indicators are constantly being developed to describe it. Among wide variety of models and developed composite indexes, a decision maker can come to even bigger dilemma than choosing one adequate risk measure. As DEA and TOPSIS are well-known mathematical models and have recently been increasingly used for risk evaluation in road safety, we used efficiencies (composite indexes) obtained by different models, based on DEA and TOPSIS, to present PROMETHEE-RS model for selection of optimal method for composite index. Method for selection of optimal composite index is based on three parameters (average correlation, average rank variation and average cluster variation) inserted into a PROMETHEE MCDM method in order to choose the optimal one. The model is tested by comparing 27 police departments in Serbia. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Generation of infrared supercontinuum radiation: spatial mode dispersion and higher-order mode propagation in ZBLAN step-index fibers

    DEFF Research Database (Denmark)

    Ramsay, Jacob Søndergaard; Dupont, Sune Vestergaard Lund; Johansen, Mikkel Willum

    2013-01-01

    Using femtosecond upconversion we investigate the time and wavelength structure of infrared supercontinuum generation. It is shown that radiation is scattered into higher order spatial modes (HOMs) when generating a supercontinuum using fibers that are not single-moded, such as a step-index ZBLAN...... fiber. As a consequence of intermodal scattering and the difference in group velocity for the modes, the supercontinuum splits up spatially and temporally. Experimental results indicate that a significant part of the radiation propagates in HOMs. Conventional simulations of super-continuum generation do...

  13. Validation of DRAGON side-step method for Bruce-A restart Phase-B physics tests

    International Nuclear Information System (INIS)

    Shen, W.; Ngo-Trong, C.; Davis, R.S.

    2004-01-01

    The DRAGON side-step method, developed at AECL, has a number of advantages over the all-DRAGON method that was used before. It is now the qualified method for reactivity-device calculations. Although the side-step-method-generated incremental cross sections have been validated against those previously calculated with the all-DRAGON method, it is highly desirable to validate the side-step method against device-worth measurements in power reactors directly. In this paper, the DRAGON side-step method was validated by comparison with the device-calibration measurements made in Bruce-A NGS Unit 4 restart Phase-B commissioning in 2003. The validation exercise showed excellent results, with the DRAGON code overestimating the measured ZCR worth by ∼5%. A sensitivity study was also performed in this paper to assess the effect of various DRAGON modelling techniques on the incremental cross sections. The assessment shows that the refinement of meshes in 3-D and the use of the side-step method are two major reasons contributing to the improved agreement between the calculated ZCR worths and the measurements. Use of different DRAGON versions, DRAGON libraries, local-parameter core conditions, and weighting techniques for the homogenization of tube clusters inside the ZCR have a very small effect on the ZCR incremental thermal absorption cross section and ZCR reactivity worth. (author)

  14. Automatic inference of indexing rules for MEDLINE

    Directory of Open Access Journals (Sweden)

    Shooshan Sonya E

    2008-11-01

    Full Text Available Abstract Background: Indexing is a crucial step in any information retrieval system. In MEDLINE, a widely used database of the biomedical literature, the indexing process involves the selection of Medical Subject Headings in order to describe the subject matter of articles. The need for automatic tools to assist MEDLINE indexers in this task is growing with the increasing number of publications being added to MEDLINE. Methods: In this paper, we describe the use and the customization of Inductive Logic Programming (ILP to infer indexing rules that may be used to produce automatic indexing recommendations for MEDLINE indexers. Results: Our results show that this original ILP-based approach outperforms manual rules when they exist. In addition, the use of ILP rules also improves the overall performance of the Medical Text Indexer (MTI, a system producing automatic indexing recommendations for MEDLINE. Conclusion: We expect the sets of ILP rules obtained in this experiment to be integrated into MTI.

  15. A new method for calculation of an air quality index

    Energy Technology Data Exchange (ETDEWEB)

    Ilvessalo, P. [Finnish Meteorological Inst., Helsinki (Finland). Air Quality Dept.

    1995-12-31

    Air quality measurement programs in Finnish towns have expanded during the last few years. As a result of this it is more and more difficult to make use of all the measured concentration data. Citizens of Finnish towns are nowadays taking more of an interest in the air quality of their surroundings. The need to describe air quality in a simplified form has increased. Air quality indices permit the presentation of air quality data in such a way that prevailing conditions are more easily understandable than when using concentration data as such. Using an air quality index always means that some of the information about concentrations of contaminants in the air will be lost. How much information is possible to extract from a single index number depends on the calculation method. A new method for the calculation of an air quality index has been developed. This index always indicates the overstepping of an air quality guideline level. The calculation of this air quality index is performed using the concentrations of all the contaminants measured. The index gives information both about the prevailing air quality and also the short-term trend. It can also warn about the expected exceeding of guidelines due to one or several contaminants. The new index is especially suitable for the real-time monitoring and notification of air quality values. The behaviour of the index was studied using material from a measurement period in the spring of 1994 in Kaepylae, Helsinki. Material from a pre-operational period in the town of Oulu was also available. (author)

  16. A new method for calculation of an air quality index

    Energy Technology Data Exchange (ETDEWEB)

    Ilvessalo, P [Finnish Meteorological Inst., Helsinki (Finland). Air Quality Dept.

    1996-12-31

    Air quality measurement programs in Finnish towns have expanded during the last few years. As a result of this it is more and more difficult to make use of all the measured concentration data. Citizens of Finnish towns are nowadays taking more of an interest in the air quality of their surroundings. The need to describe air quality in a simplified form has increased. Air quality indices permit the presentation of air quality data in such a way that prevailing conditions are more easily understandable than when using concentration data as such. Using an air quality index always means that some of the information about concentrations of contaminants in the air will be lost. How much information is possible to extract from a single index number depends on the calculation method. A new method for the calculation of an air quality index has been developed. This index always indicates the overstepping of an air quality guideline level. The calculation of this air quality index is performed using the concentrations of all the contaminants measured. The index gives information both about the prevailing air quality and also the short-term trend. It can also warn about the expected exceeding of guidelines due to one or several contaminants. The new index is especially suitable for the real-time monitoring and notification of air quality values. The behaviour of the index was studied using material from a measurement period in the spring of 1994 in Kaepylae, Helsinki. Material from a pre-operational period in the town of Oulu was also available. (author)

  17. Proposal for a Five-Step Method to Elicit Expert Judgment

    Directory of Open Access Journals (Sweden)

    Duco Veen

    2017-12-01

    Full Text Available Elicitation is a commonly used tool to extract viable information from experts. The information that is held by the expert is extracted and a probabilistic representation of this knowledge is constructed. A promising avenue in psychological research is to incorporated experts’ prior knowledge in the statistical analysis. Systematic reviews on elicitation literature however suggest that it might be inappropriate to directly obtain distributional representations from experts. The literature qualifies experts’ performance on estimating elements of a distribution as unsatisfactory, thus reliably specifying the essential elements of the parameters of interest in one elicitation step seems implausible. Providing feedback within the elicitation process can enhance the quality of the elicitation and interactive software can be used to facilitate the feedback. Therefore, we propose to decompose the elicitation procedure into smaller steps with adjustable outcomes. We represent the tacit knowledge of experts as a location parameter and their uncertainty concerning this knowledge by a scale and shape parameter. Using a feedback procedure, experts can accept the representation of their beliefs or adjust their input. We propose a Five-Step Method which consists of (1 Eliciting the location parameter using the trial roulette method. (2 Provide feedback on the location parameter and ask for confirmation or adjustment. (3 Elicit the scale and shape parameter. (4 Provide feedback on the scale and shape parameter and ask for confirmation or adjustment. (5 Use the elicited and calibrated probability distribution in a statistical analysis and update it with data or to compute a prior-data conflict within a Bayesian framework. User feasibility and internal validity for the Five-Step Method are investigated using three elicitation studies.

  18. A two-step method for developing a control rod program for boiling water reactors

    International Nuclear Information System (INIS)

    Taner, M.S.; Levine, S.H.; Hsiao, M.Y.

    1992-01-01

    This paper reports on a two-step method that is established for the generation of a long-term control rod program for boiling water reactors (BWRs). The new method assumes a time-variant target power distribution in core depletion. In the new method, the BWR control rod programming is divided into two steps. In step 1, a sequence of optimal, exposure-dependent Haling power distribution profiles is generated, utilizing the spectral shift concept. In step 2, a set of exposure-dependent control rod patterns is developed by using the Haling profiles generated at step 1 as a target. The new method is implemented in a computer program named OCTOPUS. The optimization procedure of OCTOPUS is based on the method of approximation programming, in which the SIMULATE-E code is used to determine the nucleonics characteristics of the reactor core state. In a test in cycle length over a time-invariant, target Haling power distribution case because of a moderate application of spectral shift. No thermal limits of the core were violated. The gain in cycle length could be increased further by broadening the extent of the spetral shift

  19. Validation of a One-Step Method for Extracting Fatty Acids from Salmon, Chicken and Beef Samples.

    Science.gov (United States)

    Zhang, Zhichao; Richardson, Christine E; Hennebelle, Marie; Taha, Ameer Y

    2017-10-01

    Fatty acid extraction methods are time-consuming and expensive because they involve multiple steps and copious amounts of extraction solvents. In an effort to streamline the fatty acid extraction process, this study compared the standard Folch lipid extraction method to a one-step method involving a column that selectively elutes the lipid phase. The methods were tested on raw beef, salmon, and chicken. Compared to the standard Folch method, the one-step extraction process generally yielded statistically insignificant differences in chicken and salmon fatty acid concentrations, percent composition and weight percent. Initial testing showed that beef stearic, oleic and total fatty acid concentrations were significantly lower by 9-11% with the one-step method as compared to the Folch method, but retesting on a different batch of samples showed a significant 4-8% increase in several omega-3 and omega-6 fatty acid concentrations with the one-step method relative to the Folch. Overall, the findings reflect the utility of a one-step extraction method for routine and rapid monitoring of fatty acids in chicken and salmon. Inconsistencies in beef concentrations, although minor (within 11%), may be due to matrix effects. A one-step fatty acid extraction method has broad applications for rapidly and routinely monitoring fatty acids in the food supply and formulating controlled dietary interventions. © 2017 Institute of Food Technologists®.

  20. Stability analysis and time-step limits for a Monte Carlo Compton-scattering method

    International Nuclear Information System (INIS)

    Densmore, Jeffery D.; Warsa, James S.; Lowrie, Robert B.

    2010-01-01

    A Monte Carlo method for simulating Compton scattering in high energy density applications has been presented that models the photon-electron collision kinematics exactly [E. Canfield, W.M. Howard, E.P. Liang, Inverse Comptonization by one-dimensional relativistic electrons, Astrophys. J. 323 (1987) 565]. However, implementing this technique typically requires an explicit evaluation of the material temperature, which can lead to unstable and oscillatory solutions. In this paper, we perform a stability analysis of this Monte Carlo method and develop two time-step limits that avoid undesirable behavior. The first time-step limit prevents instabilities, while the second, more restrictive time-step limit avoids both instabilities and nonphysical oscillations. With a set of numerical examples, we demonstrate the efficacy of these time-step limits.

  1. Method of making stepped photographic density standards of radiographic photographs

    International Nuclear Information System (INIS)

    Borovin, I.V.; Kondina, M.A.

    1987-01-01

    In industrial radiography practice the need often arises for a prompt evaluation of the photographic density of an x-ray film. A method of making stepped photographic density standards for industrial radiography by contact printing from a negative is described. The method is intended for industrial radiation flaw detection laboratories not having specialized sensitometric equipment

  2. Synthesis and characterization of copper nanofluid by a novel one-step method

    International Nuclear Information System (INIS)

    Kumar, S. Ananda; Meenakshi, K. Shree; Narashimhan, B.R.V.; Srikanth, S.; Arthanareeswaran, G.

    2009-01-01

    This paper presents a novel one-step method for the preparation of stable, non-agglomerated copper nanofluids by reducing copper sulphate pentahydrate with sodium hypophosphite as reducing agent in ethylene glycol as base fluid by means of conventional heating. This is an in situ, one-step method which gives high yield of product with less time consumption. The characterization of the nanofluid is done by particle size analyzer, X-ray diffraction topography, UV-vis analysis and Fourier transform infrared spectroscopy (FT-IR) followed by the study of thermal conductivity of nanofluid by the transient hot wire method

  3. Lagrangian fractional step method for the incompressible Navier--Stokes equations on a periodic domain

    International Nuclear Information System (INIS)

    Boergers, C.; Peskin, C.S.

    1987-01-01

    In the Lagrangian fractional step method introduced in this paper, the fluid velocity and pressure are defined on a collection of N fluid markers. At each time step, these markers are used to generate a Voronoi diagram, and this diagram is used to construct finite-difference operators corresponding to the divergence, gradient, and Laplacian. The splitting of the Navier--Stokes equations leads to discrete Helmholtz and Poisson problems, which we solve using a two-grid method. The nonlinear convection terms are modeled simply by the displacement of the fluid markers. We have implemented this method on a periodic domain in the plane. We describe an efficient algorithm for the numerical construction of periodic Voronoi diagrams, and we report on numerical results which indicate the the fractional step method is convergent of first order. The overall work per time step is proportional to N log N. copyright 1987 Academic Press, Inc

  4. Accurate step-FMCW ultrasound ranging and comparison with pulse-echo signaling methods

    Science.gov (United States)

    Natarajan, Shyam; Singh, Rahul S.; Lee, Michael; Cox, Brian P.; Culjat, Martin O.; Grundfest, Warren S.; Lee, Hua

    2010-03-01

    This paper presents a method setup for high-frequency ultrasound ranging based on stepped frequency-modulated continuous waves (FMCW), potentially capable of producing a higher signal-to-noise ratio (SNR) compared to traditional pulse-echo signaling. In current ultrasound systems, the use of higher frequencies (10-20 MHz) to enhance resolution lowers signal quality due to frequency-dependent attenuation. The proposed ultrasound signaling format, step-FMCW, is well-known in the radar community, and features lower peak power, wider dynamic range, lower noise figure and simpler electronics in comparison to pulse-echo systems. In pulse-echo ultrasound ranging, distances are calculated using the transmit times between a pulse and its subsequent echoes. In step-FMCW ultrasonic ranging, the phase and magnitude differences at stepped frequencies are used to sample the frequency domain. Thus, by taking the inverse Fourier transform, a comprehensive range profile is recovered that has increased immunity to noise over conventional ranging methods. Step-FMCW and pulse-echo waveforms were created using custom-built hardware consisting of an arbitrary waveform generator and dual-channel super heterodyne receiver, providing high SNR and in turn, accuracy in detection.

  5. A two-step method for rapid characterization of electroosmotic flows in capillary electrophoresis.

    Science.gov (United States)

    Zhang, Wenjing; He, Muyi; Yuan, Tao; Xu, Wei

    2017-12-01

    The measurement of electroosmotic flow (EOF) is important in a capillary electrophoresis (CE) experiment in terms of performance optimization and stability improvement. Although several methods exist, there are demanding needs to accurately characterize ultra-low electroosmotic flow rates (EOF rates), such as in coated capillaries used in protein separations. In this work, a new method, called the two-step method, was developed to accurately and rapidly measure EOF rates in a capillary, especially for measuring the ultra-low EOF rates in coated capillaries. In this two-step method, the EOF rates were calculated by measuring the migration time difference of a neutral marker in two consecutive experiments, in which a pressure driven was introduced to accelerate the migration and the DC voltage was reversed to switch the EOF direction. Uncoated capillaries were first characterized by both this two-step method and a conventional method to confirm the validity of this new method. Then this new method was applied in the study of coated capillaries. Results show that this new method is not only fast in speed, but also better in accuracy. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Transmission of laser pulses with high output beam quality using step-index fibers having large cladding

    Science.gov (United States)

    Yalin, Azer P; Joshi, Sachin

    2014-06-03

    An apparatus and method for transmission of laser pulses with high output beam quality using large core step-index silica optical fibers having thick cladding, are described. The thick cladding suppresses diffusion of modal power to higher order modes at the core-cladding interface, thereby enabling higher beam quality, M.sup.2, than are observed for large core, thin cladding optical fibers. For a given NA and core size, the thicker the cladding, the better the output beam quality. Mode coupling coefficients, D, has been found to scale approximately as the inverse square of the cladding dimension and the inverse square root of the wavelength. Output from a 2 m long silica optical fiber having a 100 .mu.m core and a 660 .mu.m cladding was found to be close to single mode, with an M.sup.2=1.6. Another thick cladding fiber (400 .mu.m core and 720 .mu.m clad) was used to transmit 1064 nm pulses of nanosecond duration with high beam quality to form gas sparks at the focused output (focused intensity of >100 GW/cm.sup.2), wherein the energy in the core was laser pulses was about 6 ns. Extending the pulse duration provided the ability to increase the delivered pulse energy (>20 mJ delivered for 50 ns pulses) without damaging the silica fiber.

  7. Incidence, risk factors, and pregnancy outcomes of gestational diabetes mellitus using one-step versus two-step diagnostic approaches: A population-based cohort study in Isfahan, Iran.

    Science.gov (United States)

    Hosseini, Elham; Janghorbani, Mohsen; Aminorroaya, Ashraf

    2018-06-01

    To study the incidence, risk factors, and pregnancy outcomes associated with gestational diabetes mellitus (GDM) diagnosed with one-step and two-step screening approaches. 1000 pregnant women who were eligible and consented to participate underwent fasting plasma glucose testing at the first prenatal visit (6-14 weeks). The women free from GDM or overt diabetes were screened at 24-28 weeks using the 50-g glucose challenge test (GCT) followed by 100-g, 3-h oral glucose tolerance test (OGTT) (two-step method). Regardless of the GCT result, all women underwent a 75-g, 2-h OGTT within one-week interval (one-step method). GDM incidence using the one-step and two-step methods was 9.3% (95% CI: 7.4-11.2) and 4.2% (95% CI: 2.9-5.5). GDM significantly increased the risk of macrosomia, gestational hypertension, preeclampsia, and cesarean section and older age and family history of diabetes significantly increased the risk of developing GDM in both approaches. In two-step method, higher pre-pregnancy body mass index and lower physical activity during pregnancy along with higher earlier cesarean section also increased significantly the risk of developing GDM. Despite a higher incidence of GDM using the one-step approach, more risk factors for and a stronger effect of GDM on adverse pregnancy outcomes were found when using the two-step approach. Longer follow-up of women with and without GDM may change the results using both approaches. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. One step linear reconstruction method for continuous wave diffuse optical tomography

    Science.gov (United States)

    Ukhrowiyah, N.; Yasin, M.

    2017-09-01

    The method one step linear reconstruction method for continuous wave diffuse optical tomography is proposed and demonstrated for polyvinyl chloride based material and breast phantom. Approximation which used in this method is selecting regulation coefficient and evaluating the difference between two states that corresponding to the data acquired without and with a change in optical properties. This method is used to recovery of optical parameters from measured boundary data of light propagation in the object. The research is demonstrated by simulation and experimental data. Numerical object is used to produce simulation data. Chloride based material and breast phantom sample is used to produce experimental data. Comparisons of results between experiment and simulation data are conducted to validate the proposed method. The results of the reconstruction image which is produced by the one step linear reconstruction method show that the image reconstruction almost same as the original object. This approach provides a means of imaging that is sensitive to changes in optical properties, which may be particularly useful for functional imaging used continuous wave diffuse optical tomography of early diagnosis of breast cancer.

  9. Bragg gratings inscription in step-index PMMA optical fiber by femtosecond laser pulses at 400 nm

    Science.gov (United States)

    Hu, X.; Kinet, D.; Chah, K.; Mégret, P.; Caucheteur, C.

    2016-05-01

    In this paper, we report photo-inscription of uniform Bragg gratings in trans-4-stilbenemethanol-doped photosensitive step-index polymer optical fiber. Gratings were produced at ~1575 nm by the phase mask technique with a femtosecond laser emitting at 400 nm with different average optical powers (8 mW, 13 mW and 20 mW). The grating growth dynamics in transmission were monitored during the manufacturing process, showing that the grating grows faster with higher power. Using 20 mW laser beam power, the reflectivity reaches 94 % (8 dB transmission loss) in 70 seconds. Finally, the gratings were characterized in temperature in the range 20 - 45 °C. The thermal sensitivity has been computed equal to - 86.6 pm/°C.

  10. One-step sol-gel imprint lithography for guided-mode resonance structures.

    Science.gov (United States)

    Huang, Yin; Liu, Longju; Johnson, Michael; C Hillier, Andrew; Lu, Meng

    2016-03-04

    Guided-mode resonance (GMR) structures consisting of sub-wavelength periodic gratings are capable of producing narrow-linewidth optical resonances. This paper describes a sol-gel-based imprint lithography method for the fabrication of submicron 1D and 2D GMR structures. This method utilizes a patterned polydimethylsiloxane (PDMS) mold to fabricate the grating coupler and waveguide for a GMR device using a sol-gel thin film in a single step. An organic-inorganic hybrid sol-gel film was selected as the imprint material because of its relatively high refractive index. The optical responses of several sol-gel GMR devices were characterized, and the experimental results were in good agreement with the results of electromagnetic simulations. The influence of processing parameters was investigated in order to determine how finely the spectral response and resonant wavelength of the GMR devices could be tuned. As an example potential application, refractometric sensing experiments were performed using a 1D sol-gel device. The results demonstrated a refractive index sensitivity of 50 nm/refractive index unit. This one-step fabrication process offers a simple, rapid, and low-cost means of fabricating GMR structures. We anticipate that this method can be valuable in the development of various GMR-based devices as it can readily enable the fabrication of complex shapes and allow the doping of optically active materials into sol-gel thin film.

  11. One-step sol–gel imprint lithography for guided-mode resonance structures

    International Nuclear Information System (INIS)

    Huang, Yin; Liu, Longju; Lu, Meng; Johnson, Michael; C Hillier, Andrew

    2016-01-01

    Guided-mode resonance (GMR) structures consisting of sub-wavelength periodic gratings are capable of producing narrow-linewidth optical resonances. This paper describes a sol–gel-based imprint lithography method for the fabrication of submicron 1D and 2D GMR structures. This method utilizes a patterned polydimethylsiloxane (PDMS) mold to fabricate the grating coupler and waveguide for a GMR device using a sol–gel thin film in a single step. An organic–inorganic hybrid sol–gel film was selected as the imprint material because of its relatively high refractive index. The optical responses of several sol–gel GMR devices were characterized, and the experimental results were in good agreement with the results of electromagnetic simulations. The influence of processing parameters was investigated in order to determine how finely the spectral response and resonant wavelength of the GMR devices could be tuned. As an example potential application, refractometric sensing experiments were performed using a 1D sol–gel device. The results demonstrated a refractive index sensitivity of 50 nm/refractive index unit. This one-step fabrication process offers a simple, rapid, and low-cost means of fabricating GMR structures. We anticipate that this method can be valuable in the development of various GMR-based devices as it can readily enable the fabrication of complex shapes and allow the doping of optically active materials into sol–gel thin film. (paper)

  12. Creating Materials with Negative Refraction Index using Topology Optimization

    DEFF Research Database (Denmark)

    Christiansen, Rasmus Ellebæk; Sigmund, Ole

    is used for regularizationand a projection step applied to obtain clean 0/1 designs. A continuation scheme is used to avoidstagnation in the optimization. Metamaterials with negative refraction index designed using this method are presented. The angular dependence of the refraction index......We apply topology optimization along with full modeling of the electromagnetic (acoustic) field to create metamaterials with negative refraction index. We believe that our approach can be used in the design of metamaterials with specific effective permittivity and permeability e.g. by adapting....... The direction of propagation for the prescribed wave is chosen to match the angle of incidence of the incoming plane wave and its position isused to select the refraction index for the slab. We introducing a continuous design field and apply The Method of Moving Asymptotes to perform the optimization. A filter...

  13. Methods for growth of relatively large step-free SiC crystal surfaces

    Science.gov (United States)

    Neudeck, Philip G. (Inventor); Powell, J. Anthony (Inventor)

    2002-01-01

    A method for growing arrays of large-area device-size films of step-free (i.e., atomically flat) SiC surfaces for semiconductor electronic device applications is disclosed. This method utilizes a lateral growth process that better overcomes the effect of extended defects in the seed crystal substrate that limited the obtainable step-free area achievable by prior art processes. The step-free SiC surface is particularly suited for the heteroepitaxial growth of 3C (cubic) SiC, AlN, and GaN films used for the fabrication of both surface-sensitive devices (i.e., surface channel field effect transistors such as HEMT's and MOSFET's) as well as high-electric field devices (pn diodes and other solid-state power switching devices) that are sensitive to extended crystal defects.

  14. Efficient Multilevel and Multi-index Sampling Methods in Stochastic Differential Equations

    KAUST Repository

    Haji-Ali, Abdul Lateef

    2016-05-22

    of this thesis is the novel Multi-index Monte Carlo (MIMC) method which is an extension of MLMC in high dimensional problems with significant computational savings. Under reasonable assumptions on the weak and variance convergence, which are related to the mixed regularity of the underlying problem and the discretization method, the order of the computational complexity of MIMC is, at worst up to a logarithmic factor, independent of the dimensionality of the underlying parametric equation. We also apply the same multi-index methodology to another sampling method, namely the Stochastic Collocation method. Hence, the novel Multi-index Stochastic Collocation method is proposed and is shown to be more efficient in problems with sufficient mixed regularity than our novel MIMC method and other standard methods. Finally, MIMC is applied to approximate quantities of interest of stochastic particle systems in the mean-field when the number of particles tends to infinity. To approximate these quantities of interest up to an error tolerance, TOL, MIMC has a computational complexity of O(TOL-2log(TOL)2). This complexity is achieved by building a hierarchy based on two discretization parameters: the number of time steps in an Milstein scheme and the number of particles in the particle system. Moreover, we use a partitioning estimator to increase the correlation between two stochastic particle systems with different sizes. In comparison, the optimal computational complexity of MLMC in this case is O(TOL-3) and the computational complexity of Monte Carlo is O(TOL-4).

  15. Analysis in indexing

    DEFF Research Database (Denmark)

    Mai, Jens Erik

    2005-01-01

    is presented as an alternative and the paper discusses how this approach includes a broader range of analyses and how it requires a new set of actions from using this approach; analysis of the domain, users and indexers. The paper concludes that the two-step procedure to indexing is insufficient to explain...

  16. The Refractive Index Measurement Of Silicon Dioxide Thin Film by the Coupling Prism Method

    International Nuclear Information System (INIS)

    Budianto, Anwar; Hariyanto, Sigit; Subarkah

    1996-01-01

    Refractive index of silicon dioxide thin film that doped with phosphor (SiO 2 :P) above the pure silicon dioxide substrate has been measured by light coupling prism method. The method principle is focusing the light on coupling prism base so that the light propagates into the waveguide layer while the reflected one forms a mode in the observation plane. The SiO 2 thin film as waveguide layer has a refractive index that give the thick and refractive index relation. The He-Ne laser as light source has the wavelength λ 0,6328 μm. The refractive index measurement of the thin film with the substrate refractive index n sb = 1,47 and the thin film thick d = 2μm gives n g = 1,5534 ± 0,01136. This method can distinguish the refractive index of thin film about 6% to the refractive index of substrate

  17. Aerial robot intelligent control method based on back-stepping

    Science.gov (United States)

    Zhou, Jian; Xue, Qian

    2018-05-01

    The aerial robot is characterized as strong nonlinearity, high coupling and parameter uncertainty, a self-adaptive back-stepping control method based on neural network is proposed in this paper. The uncertain part of the aerial robot model is compensated online by the neural network of Cerebellum Model Articulation Controller and robust control items are designed to overcome the uncertainty error of the system during online learning. At the same time, particle swarm algorithm is used to optimize and fix parameters so as to improve the dynamic performance, and control law is obtained by the recursion of back-stepping regression. Simulation results show that the designed control law has desired attitude tracking performance and good robustness in case of uncertainties and large errors in the model parameters.

  18. Interferometric investigation and simulation of refractive index in glass matrixes containing nanoparticles of varying sizes

    Energy Technology Data Exchange (ETDEWEB)

    Feeney, Michael Gerard; Ince, Rabia; Yukselici, Mehmet Hikmet; Allahverdi, Cagdas

    2011-07-01

    The relationship between refractive index and nanoparticle radii of cadmium selenide (CdSe) nanoparticles embedded within glass matrixes was investigated experimentally and by simulations. A homemade automated Michelson interferometer arrangement employing a rotating table and a He-Ne laser source at a wavelength of 632.8 nm determined the refractive index versus nanoparticle radii of embedded cadmium selenide (CdSe) nanoparticles. The refractive index was found to decrease linearly with nanoparticle radius increase. However, one sample showed a step increase in refractive index; on spectroscopic analysis, it was found that its resonant wavelength matched that of the He-Ne source wavelength. The simulations showed that two conditions caused the step increase in refractive index: low plasma frequency and matched sample and source resonances. This simple interferometer setup defines a new method of determining the radii of nanoparticles embedded in substrates and enables refractive index tailoring by modification of exact annealing conditions.

  19. SPAR-H Step-by-Step Guidance

    Energy Technology Data Exchange (ETDEWEB)

    April M. Whaley; Dana L. Kelly; Ronald L. Boring; William J. Galyean

    2012-06-01

    Step-by-step guidance was developed recently at Idaho National Laboratory for the US Nuclear Regulatory Commission on the use of the Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method for quantifying Human Failure Events (HFEs). This work was done to address SPAR-H user needs, specifically requests for additional guidance on the proper application of various aspects of the methodology. This paper overviews the steps of the SPAR-H analysis process and highlights some of the most important insights gained during the development of the step-by-step directions. This supplemental guidance for analysts is applicable when plant-specific information is available, and goes beyond the general guidance provided in existing SPAR-H documentation. The steps highlighted in this paper are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff.

  20. Two-step method for creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy.

    Science.gov (United States)

    Liu, Yu; Li, Ji-Jia; Zu, Peng; Liu, Hong-Xu; Yu, Zhan-Wu; Ren, Yi

    2017-12-07

    To introduce a two-step method for creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy and assess its clinical application. One hundred and twenty-two patients with middle or lower esophageal cancer who underwent laparoscopic-thoracoscopic Ivor-Lewis esophagectomy at Liaoning Cancer Hospital and Institute from March 2014 to March 2016 were included in this study, and divided into two groups based on the procedure used for creating a gastric tube. One group used a two-step method for creating a gastric tube, and the other group used the conventional method. The two groups were compared regarding the operating time, surgical complications, and number of stapler cartridges used. The mean operating time was significantly shorter in the two-step method group than in the conventional method group [238 (179-293) min vs 272 (189-347) min, P creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy has the advantages of simple operation, minimal damage to the tubular stomach, and reduced use of stapler cartridges.

  1. A Three Step Explicit Method for Direct Solution of Third Order ...

    African Journals Online (AJOL)

    This study produces a three step discrete Linear Multistep Method for Direct solution of third order initial value problems of ordinary differential equations of the form y'''= f(x,y,y',y''). Taylor series expansion technique was adopted in the development of the method. The differential system from the basis polynomial function to ...

  2. Two-step calibration method for multi-algorithm score-based face recognition systems by minimizing discrimination loss

    NARCIS (Netherlands)

    Susyanto, N.; Veldhuis, R.N.J.; Spreeuwers, L.J.; Klaassen, C.A.J.; Fierrez, J.; Li, S.Z.; Ross, A.; Veldhuis, R.; Alonso-Fernandez, F.; Bigun, J.

    2016-01-01

    We propose a new method for combining multi-algorithm score-based face recognition systems, which we call the two-step calibration method. Typically, algorithms for face recognition systems produce dependent scores. The two-step method is based on parametric copulas to handle this dependence. Its

  3. Design of a Two-Step Calibration Method of Kinematic Parameters for Serial Robots

    Science.gov (United States)

    WANG, Wei; WANG, Lei; YUN, Chao

    2017-03-01

    Serial robots are used to handle workpieces with large dimensions, and calibrating kinematic parameters is one of the most efficient ways to upgrade their accuracy. Many models are set up to investigate how many kinematic parameters can be identified to meet the minimal principle, but the base frame and the kinematic parameter are indistinctly calibrated in a one-step way. A two-step method of calibrating kinematic parameters is proposed to improve the accuracy of the robot's base frame and kinematic parameters. The forward kinematics described with respect to the measuring coordinate frame are established based on the product-of-exponential (POE) formula. In the first step the robot's base coordinate frame is calibrated by the unit quaternion form. The errors of both the robot's reference configuration and the base coordinate frame's pose are equivalently transformed to the zero-position errors of the robot's joints. The simplified model of the robot's positioning error is established in second-power explicit expressions. Then the identification model is finished by the least square method, requiring measuring position coordinates only. The complete subtasks of calibrating the robot's 39 kinematic parameters are finished in the second step. It's proved by a group of calibration experiments that by the proposed two-step calibration method the average absolute accuracy of industrial robots is updated to 0.23 mm. This paper presents that the robot's base frame should be calibrated before its kinematic parameters in order to upgrade its absolute positioning accuracy.

  4. Development of car theft crime index in peninsular Malaysia

    Science.gov (United States)

    Zulkifli, Malina; Ismail, Noriszura; Razali, Ahmad Mahir; Kasim, Maznah Mat

    2014-06-01

    Vehicle theft is classified as property crime and is considered as the most frequently reported crime in Malaysia. The rising number of vehicle thefts requires proper control by relevant authorities, especially through planning and implementation of strategic and effective measures. Nevertheless, the effort to control this crime would be much easier if there is an indication or index which is more specific to vehicle theft. This study aims to build an index crime which is specific to vehicle theft. The development of vehicle theft index proposed in this study requires three main steps; the first involves identification of criteria related to vehicle theft, the second requires calculation of degrees of importance, or weighting criteria, which involves application of correlation and entropy methods, and the final involves building of vehicle theft index using method of linear combination, or weighted arithmetic average. The results show that the two methods used for determining weights of vehicle theft index are similar. Information generated from the results can be used as a primary source for local authorities to plan strategies for reduction of vehicle theft and for insurance companies to determine premium rates of automobile insurance.

  5. The large discretization step method for time-dependent partial differential equations

    Science.gov (United States)

    Haras, Zigo; Taasan, Shlomo

    1995-01-01

    A new method for the acceleration of linear and nonlinear time dependent calculations is presented. It is based on the Large Discretization Step (LDS) approximation, defined in this work, which employs an extended system of low accuracy schemes to approximate a high accuracy discrete approximation to a time dependent differential operator. Error bounds on such approximations are derived. These approximations are efficiently implemented in the LDS methods for linear and nonlinear hyperbolic equations, presented here. In these algorithms the high and low accuracy schemes are interpreted as the same discretization of a time dependent operator on fine and coarse grids, respectively. Thus, a system of correction terms and corresponding equations are derived and solved on the coarse grid to yield the fine grid accuracy. These terms are initialized by visiting the fine grid once in many coarse grid time steps. The resulting methods are very general, simple to implement and may be used to accelerate many existing time marching schemes.

  6. Pattern Decomposition Method and a New Vegetation Index for Hyper-Multispectral Satellite Data Analysis

    Science.gov (United States)

    Muramatsu, K.; Furumi, S.; Hayashi, A.; Shiono, Y.; Ono, A.; Fujiwara, N.; Daigo, M.; Ochiai, F.

    We have developed the ``pattern decomposition method'' based on linear spectral mixing of ground objects for n-dimensional satellite data. In this method, spectral response patterns for each pixel in an image are decomposed into three components using three standard spectral shape patterns determined from the image data. Applying this method to AMSS (Airborne Multi-Spectral Scanner) data, eighteen-dimensional data are successfully transformed into three-dimensional data. Using the three components, we have developed a new vegetation index in which all the multispectral data are reflected. We consider that the index should be linear to the amount of vegetation and vegetation vigor. To validate the index, its relations to vegetation types, vegetation cover ratio, and chlorophyll contents of a leaf were studied using spectral reflectance data measured in the field with a spectrometer. The index was sensitive to vegetation types and vegetation vigor. This method and index are very useful for assessment of vegetation vigor, classifying land cover types and monitoring vegetation changes

  7. Finite element method for radiation heat transfer in multi-dimensional graded index medium

    International Nuclear Information System (INIS)

    Liu, L.H.; Zhang, L.; Tan, H.P.

    2006-01-01

    In graded index medium, ray goes along a curved path determined by Fermat principle, and curved ray-tracing is very difficult and complex. To avoid the complicated and time-consuming computation of curved ray trajectories, a finite element method based on discrete ordinate equation is developed to solve the radiative transfer problem in a multi-dimensional semitransparent graded index medium. Two particular test problems of radiative transfer are taken as examples to verify this finite element method. The predicted dimensionless net radiative heat fluxes are determined by the proposed method and compared with the results obtained by finite volume method. The results show that the finite element method presented in this paper has a good accuracy in solving the multi-dimensional radiative transfer problem in semitransparent graded index medium

  8. Ion-step method for surface potential sensing of silicon nanowires

    NARCIS (Netherlands)

    Chen, S.; van Nieuwkasteele, Jan William; van den Berg, Albert; Eijkel, Jan C.T.

    2016-01-01

    This paper presents a novel stimulus-response method for surface potential sensing of silicon nanowire (Si NW) field-effect transistors. When an "ion-step" from low to high ionic strength is given as a stimulus to the gate oxide surface, an increase of double layer capacitance is therefore expected.

  9. Computer Aided Analysis of TM-Multimode Planar Graded-index Optical Waveguides

    International Nuclear Information System (INIS)

    Ashry, M.; Nasr, A.S.; Abou El-Fadl, A.A.

    2000-01-01

    An algorithm is developed for analysis TM-Multimode Planar graded-index optical waveguides. A Modified Impedance Boundary Method of Moments (MIBMOM) for the analysis of planar graded-index optical waveguide structures is presented. The algorithm is used to calculate the dispersion characteristics and the field distribution of TM-multimode planar graded-index optical waveguides. The technique is based on Galerkin s procedure and the exact boundary condition at the interfaces between the graded index region and the step index cladding. Legendre polynomials are used as basis functions. The efficiency of this algorithm is examined with waveguides having various index profiles such as exponential, Gaussian and complementary error functions. The advantage of the MIBMOM is the complete solution of TM-multimode as presented which is very difficult by the other methods. With this algorithm a minimum number of basis functions to give accurate results is used. The obtained results show good agreement with the experimental results

  10. Improving genetic evaluation of litter size and piglet mortality for both genotyped and nongenotyped individuals using a single-step method.

    Science.gov (United States)

    Guo, X; Christensen, O F; Ostersen, T; Wang, Y; Lund, M S; Su, G

    2015-02-01

    A single-step method allows genetic evaluation using information of phenotypes, pedigree, and markers from genotyped and nongenotyped individuals simultaneously. This paper compared genomic predictions obtained from a single-step BLUP (SSBLUP) method, a genomic BLUP (GBLUP) method, a selection index blending (SELIND) method, and a traditional pedigree-based method (BLUP) for total number of piglets born (TNB), litter size at d 5 after birth (LS5), and mortality rate before d 5 (Mort; including stillbirth) in Danish Landrace and Yorkshire pigs. Data sets of 778,095 litters from 309,362 Landrace sows and 472,001 litters from 190,760 Yorkshire sows were used for the analysis. There were 332,795 Landrace and 207,255 Yorkshire animals in the pedigree data, among which 3,445 Landrace pigs (1,366 boars and 2,079 sows) and 3,372 Yorkshire pigs (1,241 boars and 2,131 sows) were genotyped with the Illumina PorcineSNP60 BeadChip. The results showed that the 3 methods with marker information (SSBLUP, GBLUP, and SELIND) produced more accurate predictions for genotyped animals than the pedigree-based method. For genotyped animals, the average of reliabilities for all traits in both breeds using traditional BLUP was 0.091, which increased to 0.171 w+hen using GBLUP and to 0.179 when using SELIND and further increased to 0.209 when using SSBLUP. Furthermore, the average reliability of EBV for nongenotyped animals was increased from 0.091 for traditional BLUP to 0.105 for the SSBLUP. The results indicate that the SSBLUP is a good approach to practical genomic prediction of litter size and piglet mortality in Danish Landrace and Yorkshire populations.

  11. Piloting a generic cancer consumer quality index in six European countries

    NARCIS (Netherlands)

    Wind, Anke; Roeling, Mark Patrick; Heerink, Jana; Sixma, Herman; Presti, Pietro; Lombardo, Claudio; van Harten, Wim

    2016-01-01

    Background: Accounting for patients' perspective has become increasingly important. Based on the Consumer Quality Index method (founded on Consumer Assessment of Healthcare Providers and Systems) a questionnaire was recently developed for Dutch cancer patients. As a next step, this study aimed to

  12. Piloting a generic cancer consumer quality index in six European countries.

    NARCIS (Netherlands)

    Wind, A.; Roeling, M.P.; Heerink, J.; Sixma, H.; Presti, P.; Lombardo, C.; Harten, W. van

    2016-01-01

    Background: Accounting for patients’ perspective has become increasingly important. Based on the Consumer Quality Index method (founded on Consumer Assessment of Healthcare Providers and Systems) a questionnaire was recently developed for Dutch cancer patients. As a next step, this study aimed to

  13. Nondestructive measurement of refractive index profile of optical fiber preforms using moire technique and phase shift method

    Science.gov (United States)

    Ranjbar, Samaneh; Khalesifard, Hamid R.; Rasouli, Saifollah

    2006-01-01

    The refractive index profile of optical fiber preform is measured by a nondestructive technique based on Talbot interferometry. In this technique the preform is placed between two ronchi ruling gratings of 10 lines/mm and the system is illuminated by an expanded and collimated beam of He-Ne laser. In this arrangement the 2nd grating is positioned in the Talbot image of the 1st grating and the preform axis is parallel to the gratings planes. To eliminate the effect of clad on the light beam deflection during the measurements, the preform is immersed in an index matching liquid. The phase front of the laser light over the 2nd grating can be monitored by analysis of the moire pattern which is formed over there. The analysis is done by means of 4-step phase shift technique. In this technique the second grating is moved in four steps of 1/4 of the grating vector and in each step the intensity profile of the moire pattern is recorded. The phasefront can be specified by using the recorded intensities. The refractive index profile of the preform can be calculated from the changes on phasefront while the preform is placed between the gratings respect to the case when it is absent. The whole procedure is automated and computer controlled by using a CCD camera to record the moire fringes, a stepper motor for linear translation of the 2nd grating and a code in MATLAB to control the system and measurements.

  14. A Dimensionality Reduction-Based Multi-Step Clustering Method for Robust Vessel Trajectory Analysis

    Directory of Open Access Journals (Sweden)

    Huanhuan Li

    2017-08-01

    Full Text Available The Shipboard Automatic Identification System (AIS is crucial for navigation safety and maritime surveillance, data mining and pattern analysis of AIS information have attracted considerable attention in terms of both basic research and practical applications. Clustering of spatio-temporal AIS trajectories can be used to identify abnormal patterns and mine customary route data for transportation safety. Thus, the capacities of navigation safety and maritime traffic monitoring could be enhanced correspondingly. However, trajectory clustering is often sensitive to undesirable outliers and is essentially more complex compared with traditional point clustering. To overcome this limitation, a multi-step trajectory clustering method is proposed in this paper for robust AIS trajectory clustering. In particular, the Dynamic Time Warping (DTW, a similarity measurement method, is introduced in the first step to measure the distances between different trajectories. The calculated distances, inversely proportional to the similarities, constitute a distance matrix in the second step. Furthermore, as a widely-used dimensional reduction method, Principal Component Analysis (PCA is exploited to decompose the obtained distance matrix. In particular, the top k principal components with above 95% accumulative contribution rate are extracted by PCA, and the number of the centers k is chosen. The k centers are found by the improved center automatically selection algorithm. In the last step, the improved center clustering algorithm with k clusters is implemented on the distance matrix to achieve the final AIS trajectory clustering results. In order to improve the accuracy of the proposed multi-step clustering algorithm, an automatic algorithm for choosing the k clusters is developed according to the similarity distance. Numerous experiments on realistic AIS trajectory datasets in the bridge area waterway and Mississippi River have been implemented to compare our

  15. A Dimensionality Reduction-Based Multi-Step Clustering Method for Robust Vessel Trajectory Analysis.

    Science.gov (United States)

    Li, Huanhuan; Liu, Jingxian; Liu, Ryan Wen; Xiong, Naixue; Wu, Kefeng; Kim, Tai-Hoon

    2017-08-04

    The Shipboard Automatic Identification System (AIS) is crucial for navigation safety and maritime surveillance, data mining and pattern analysis of AIS information have attracted considerable attention in terms of both basic research and practical applications. Clustering of spatio-temporal AIS trajectories can be used to identify abnormal patterns and mine customary route data for transportation safety. Thus, the capacities of navigation safety and maritime traffic monitoring could be enhanced correspondingly. However, trajectory clustering is often sensitive to undesirable outliers and is essentially more complex compared with traditional point clustering. To overcome this limitation, a multi-step trajectory clustering method is proposed in this paper for robust AIS trajectory clustering. In particular, the Dynamic Time Warping (DTW), a similarity measurement method, is introduced in the first step to measure the distances between different trajectories. The calculated distances, inversely proportional to the similarities, constitute a distance matrix in the second step. Furthermore, as a widely-used dimensional reduction method, Principal Component Analysis (PCA) is exploited to decompose the obtained distance matrix. In particular, the top k principal components with above 95% accumulative contribution rate are extracted by PCA, and the number of the centers k is chosen. The k centers are found by the improved center automatically selection algorithm. In the last step, the improved center clustering algorithm with k clusters is implemented on the distance matrix to achieve the final AIS trajectory clustering results. In order to improve the accuracy of the proposed multi-step clustering algorithm, an automatic algorithm for choosing the k clusters is developed according to the similarity distance. Numerous experiments on realistic AIS trajectory datasets in the bridge area waterway and Mississippi River have been implemented to compare our proposed method with

  16. Quality Index Method developed for gutted and ungutted red tilapia (Oreochromis ssp

    Directory of Open Access Journals (Sweden)

    Nelson Gutiérrez G.

    2015-01-01

    Full Text Available Objective. To develop a Quality Index Method (QIM for gutted and ungutted red tilapia from aquaculture ponds. Materials and methods. 40 specimens of gutted red tilapia and 40 ungutted ones were located in foam polyethylene boxes within layers of ice and storage at 4°C. Three fish were randomly sampled on days 0, 3, 5, 8, 11, 14 and 17 for gutted tilapia, and on days 0, 3, 6, 9, 11, 14 and 16 for ungutted tilapia. A sensorial panel of 8 experts was formed to evaluate the product. With three samples each day with average points of the sensorial attributes proposed in the method, the quality index for gutted and ungutted red tilapia was obtained based on the storage time on ice. Results. The Quality Index Method obtained for gutted and ungutted red tilapia showed maximum values of 21 and 29, respectively. It was adjusted in an increasing lineal model with high correlation between the Quality Index and the storage time on ice. Conclusions. The developed model is useful to determine deterioration levels and to define storage and consumption time. For gutted red tilapia the panel rejected the fish after 8 - 11 days of storage whereas the ungutted red tilapia was rejected after 6 - 9 days.

  17. Method of determining dispersion dependence of refractive index of nanospheres building opals

    Science.gov (United States)

    Kępińska, Mirosława; Starczewska, Anna; Duka, Piotr

    2017-11-01

    The method of determining dispersion dependence of refractive index of nanospheres building opals is presented. In this method basing on angular dependences of the spectral positions of Bragg diffraction minima on transmission spectra for opal series of known spheres diameter, the spectrum of effective refractive index for opals and then refractive index for material building opal's spheres is determined. The described procedure is used for determination of neff(λ) for opals and nsph(λ) for material which spheres building investigated opals are made of. The obtained results are compared with literature data of nSiO2(λ) considered in the analysis and interpretation of extremes related to the light diffraction at (hkl) SiO2 opal planes.

  18. A single-step method for rapid extraction of total lipids from green microalgae.

    Directory of Open Access Journals (Sweden)

    Martin Axelsson

    Full Text Available Microalgae produce a wide range of lipid compounds of potential commercial interest. Total lipid extraction performed by conventional extraction methods, relying on the chloroform-methanol solvent system are too laborious and time consuming for screening large numbers of samples. In this study, three previous extraction methods devised by Folch et al. (1957, Bligh and Dyer (1959 and Selstam and Öquist (1985 were compared and a faster single-step procedure was developed for extraction of total lipids from green microalgae. In the single-step procedure, 8 ml of a 2∶1 chloroform-methanol (v/v mixture was added to fresh or frozen microalgal paste or pulverized dry algal biomass contained in a glass centrifuge tube. The biomass was manually suspended by vigorously shaking the tube for a few seconds and 2 ml of a 0.73% NaCl water solution was added. Phase separation was facilitated by 2 min of centrifugation at 350 g and the lower phase was recovered for analysis. An uncharacterized microalgal polyculture and the green microalgae Scenedesmus dimorphus, Selenastrum minutum, and Chlorella protothecoides were subjected to the different extraction methods and various techniques of biomass homogenization. The less labour intensive single-step procedure presented here allowed simultaneous recovery of total lipid extracts from multiple samples of green microalgae with quantitative yields and fatty acid profiles comparable to those of the previous methods. While the single-step procedure is highly correlated in lipid extractability (r² = 0.985 to the previous method of Folch et al. (1957, it allowed at least five times higher sample throughput.

  19. A stabilized Runge–Kutta–Legendre method for explicit super-time-stepping of parabolic and mixed equations

    International Nuclear Information System (INIS)

    Meyer, Chad D.; Balsara, Dinshaw S.; Aslam, Tariq D.

    2014-01-01

    Parabolic partial differential equations appear in several physical problems, including problems that have a dominant hyperbolic part coupled to a sub-dominant parabolic component. Explicit methods for their solution are easy to implement but have very restrictive time step constraints. Implicit solution methods can be unconditionally stable but have the disadvantage of being computationally costly or difficult to implement. Super-time-stepping methods for treating parabolic terms in mixed type partial differential equations occupy an intermediate position. In such methods each superstep takes “s” explicit Runge–Kutta-like time-steps to advance the parabolic terms by a time-step that is s 2 times larger than a single explicit time-step. The expanded stability is usually obtained by mapping the short recursion relation of the explicit Runge–Kutta scheme to the recursion relation of some well-known, stable polynomial. Prior work has built temporally first- and second-order accurate super-time-stepping methods around the recursion relation associated with Chebyshev polynomials. Since their stability is based on the boundedness of the Chebyshev polynomials, these methods have been called RKC1 and RKC2. In this work we build temporally first- and second-order accurate super-time-stepping methods around the recursion relation associated with Legendre polynomials. We call these methods RKL1 and RKL2. The RKL1 method is first-order accurate in time; the RKL2 method is second-order accurate in time. We verify that the newly-designed RKL1 and RKL2 schemes have a very desirable monotonicity preserving property for one-dimensional problems – a solution that is monotone at the beginning of a time step retains that property at the end of that time step. It is shown that RKL1 and RKL2 methods are stable for all values of the diffusion coefficient up to the maximum value. We call this a convex monotonicity preserving property and show by examples that it is very useful

  20. Convergence and Stability of the Split-Step θ-Milstein Method for Stochastic Delay Hopfield Neural Networks

    Directory of Open Access Journals (Sweden)

    Qian Guo

    2013-01-01

    Full Text Available A new splitting method designed for the numerical solutions of stochastic delay Hopfield neural networks is introduced and analysed. Under Lipschitz and linear growth conditions, this split-step θ-Milstein method is proved to have a strong convergence of order 1 in mean-square sense, which is higher than that of existing split-step θ-method. Further, mean-square stability of the proposed method is investigated. Numerical experiments and comparisons with existing methods illustrate the computational efficiency of our method.

  1. Safer Roads: Comparisons Between Road Assessment Program and Composite Road Safety Index Method

    Directory of Open Access Journals (Sweden)

    Mohd Razelan Intan Suhana

    2017-01-01

    Full Text Available In most countries, crash statistics have becoming very crucial in evaluating road’s safety level. In Malaysia, these data are very important in deciding crash-prone areas known as black spot where specific road improvements plan will be proposed. However due to the unavailability of reliable crash data in many developing countries, appropriate road maintenance measures are facing great troubles. In light of that, several proactive methods in defining road’s safety level such as Road Assessment Program (RAP have emerged. This research aim to compare two proactive methods that have been tested in Malaysian roads ; road assessment program and road environment risk index which was developed based on composite index theory in defining road’s safety level. Composite road environment risk index was combining several crucial environment indicators, assigning weight and aggregating the individual index together to form a single value representing the road’s safety level. Based on the results, it can be concluded that both road assessment program and composite road environment risk index are contradicted in six different ways such as type of speed used, type of analysis used and their final outcomes. However, with an aim to promote safer roads, these two methods can be used concurrently as the outcomes in both methods seems to fulfil each other’s gap very well.

  2. Improving method for calculating integral index of personnel security of company

    Directory of Open Access Journals (Sweden)

    Chjan Khao Yui

    2016-06-01

    Full Text Available The paper improves the method of calculating the integral index of personnel security of a company. The author has identified four components of personnel security (social and motivational safety, occupational safety, not confliction security, life safety which are characterized by certain indicators. Integral index of personnel security is designed for the enterprises of machine-building sector in Kharkov region, taking into account theweight coefficients j-th component of bj, and weighting factors that determine the degree of contribution of the ith parameter in the integral index aіj as defined by experts.

  3. One-step leapfrog ADI-FDTD method for simulating electromagnetic wave propagation in general dispersive media.

    Science.gov (United States)

    Wang, Xiang-Hua; Yin, Wen-Yan; Chen, Zhi Zhang David

    2013-09-09

    The one-step leapfrog alternating-direction-implicit finite-difference time-domain (ADI-FDTD) method is reformulated for simulating general electrically dispersive media. It models material dispersive properties with equivalent polarization currents. These currents are then solved with the auxiliary differential equation (ADE) and then incorporated into the one-step leapfrog ADI-FDTD method. The final equations are presented in the form similar to that of the conventional FDTD method but with second-order perturbation. The adapted method is then applied to characterize (a) electromagnetic wave propagation in a rectangular waveguide loaded with a magnetized plasma slab, (b) transmission coefficient of a plane wave normally incident on a monolayer graphene sheet biased by a magnetostatic field, and (c) surface plasmon polaritons (SPPs) propagation along a monolayer graphene sheet biased by an electrostatic field. The numerical results verify the stability, accuracy and computational efficiency of the proposed one-step leapfrog ADI-FDTD algorithm in comparison with analytical results and the results obtained with the other methods.

  4. Multi-Index Stochastic Collocation for random PDEs

    KAUST Repository

    Haji Ali, Abdul Lateef

    2016-03-28

    In this work we introduce the Multi-Index Stochastic Collocation method (MISC) for computing statistics of the solution of a PDE with random data. MISC is a combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. We propose an optimization procedure to select the most effective mixed differences to include in the MISC estimator: such optimization is a crucial step and allows us to build a method that, provided with sufficient solution regularity, is potentially more effective than other multi-level collocation methods already available in literature. We then provide a complexity analysis that assumes decay rates of product type for such mixed differences, showing that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one dimensional problem. We show the effectiveness of MISC with some computational tests, comparing it with other related methods available in the literature, such as the Multi-Index and Multilevel Monte Carlo, Multilevel Stochastic Collocation, Quasi Optimal Stochastic Collocation and Sparse Composite Collocation methods.

  5. Multi-Index Stochastic Collocation for random PDEs

    KAUST Repository

    Haji Ali, Abdul Lateef; Nobile, Fabio; Tamellini, Lorenzo; Tempone, Raul

    2016-01-01

    In this work we introduce the Multi-Index Stochastic Collocation method (MISC) for computing statistics of the solution of a PDE with random data. MISC is a combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. We propose an optimization procedure to select the most effective mixed differences to include in the MISC estimator: such optimization is a crucial step and allows us to build a method that, provided with sufficient solution regularity, is potentially more effective than other multi-level collocation methods already available in literature. We then provide a complexity analysis that assumes decay rates of product type for such mixed differences, showing that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one dimensional problem. We show the effectiveness of MISC with some computational tests, comparing it with other related methods available in the literature, such as the Multi-Index and Multilevel Monte Carlo, Multilevel Stochastic Collocation, Quasi Optimal Stochastic Collocation and Sparse Composite Collocation methods.

  6. Recursive regularization step for high-order lattice Boltzmann methods

    Science.gov (United States)

    Coreixas, Christophe; Wissocq, Gauthier; Puigt, Guillaume; Boussuge, Jean-François; Sagaut, Pierre

    2017-09-01

    A lattice Boltzmann method (LBM) with enhanced stability and accuracy is presented for various Hermite tensor-based lattice structures. The collision operator relies on a regularization step, which is here improved through a recursive computation of nonequilibrium Hermite polynomial coefficients. In addition to the reduced computational cost of this procedure with respect to the standard one, the recursive step allows to considerably enhance the stability and accuracy of the numerical scheme by properly filtering out second- (and higher-) order nonhydrodynamic contributions in under-resolved conditions. This is first shown in the isothermal case where the simulation of the doubly periodic shear layer is performed with a Reynolds number ranging from 104 to 106, and where a thorough analysis of the case at Re=3 ×104 is conducted. In the latter, results obtained using both regularization steps are compared against the Bhatnagar-Gross-Krook LBM for standard (D2Q9) and high-order (D2V17 and D2V37) lattice structures, confirming the tremendous increase of stability range of the proposed approach. Further comparisons on thermal and fully compressible flows, using the general extension of this procedure, are then conducted through the numerical simulation of Sod shock tubes with the D2V37 lattice. They confirm the stability increase induced by the recursive approach as compared with the standard one.

  7. Sediment acoustic index method for computing continuous suspended-sediment concentrations

    Science.gov (United States)

    Landers, Mark N.; Straub, Timothy D.; Wood, Molly S.; Domanski, Marian M.

    2016-07-11

    Suspended-sediment characteristics can be computed using acoustic indices derived from acoustic Doppler velocity meter (ADVM) backscatter data. The sediment acoustic index method applied in these types of studies can be used to more accurately and cost-effectively provide time-series estimates of suspended-sediment concentration and load, which is essential for informed solutions to many sediment-related environmental, engineering, and agricultural concerns. Advantages of this approach over other sediment surrogate methods include: (1) better representation of cross-sectional conditions from large measurement volumes, compared to other surrogate instruments that measure data at a single point; (2) high temporal resolution of collected data; (3) data integrity when biofouling is present; and (4) less rating curve hysteresis compared to streamflow as a surrogate. An additional advantage of this technique is the potential expansion of monitoring suspended-sediment concentrations at sites with existing ADVMs used in streamflow velocity monitoring. This report provides much-needed standard techniques for sediment acoustic index methods to help ensure accurate and comparable documented results.

  8. Deep Hashing Based Fusing Index Method for Large-Scale Image Retrieval

    Directory of Open Access Journals (Sweden)

    Lijuan Duan

    2017-01-01

    Full Text Available Hashing has been widely deployed to perform the Approximate Nearest Neighbor (ANN search for the large-scale image retrieval to solve the problem of storage and retrieval efficiency. Recently, deep hashing methods have been proposed to perform the simultaneous feature learning and the hash code learning with deep neural networks. Even though deep hashing has shown the better performance than traditional hashing methods with handcrafted features, the learned compact hash code from one deep hashing network may not provide the full representation of an image. In this paper, we propose a novel hashing indexing method, called the Deep Hashing based Fusing Index (DHFI, to generate a more compact hash code which has stronger expression ability and distinction capability. In our method, we train two different architecture’s deep hashing subnetworks and fuse the hash codes generated by the two subnetworks together to unify images. Experiments on two real datasets show that our method can outperform state-of-the-art image retrieval applications.

  9. Comparing the index-flood and multiple-regression methods using L-moments

    Science.gov (United States)

    Malekinezhad, H.; Nachtnebel, H. P.; Klik, A.

    In arid and semi-arid regions, the length of records is usually too short to ensure reliable quantile estimates. Comparing index-flood and multiple-regression analyses based on L-moments was the main objective of this study. Factor analysis was applied to determine main influencing variables on flood magnitude. Ward’s cluster and L-moments approaches were applied to several sites in the Namak-Lake basin in central Iran to delineate homogeneous regions based on site characteristics. Homogeneity test was done using L-moments-based measures. Several distributions were fitted to the regional flood data and index-flood and multiple-regression methods as two regional flood frequency methods were compared. The results of factor analysis showed that length of main waterway, compactness coefficient, mean annual precipitation, and mean annual temperature were the main variables affecting flood magnitude. The study area was divided into three regions based on the Ward’s method of clustering approach. The homogeneity test based on L-moments showed that all three regions were acceptably homogeneous. Five distributions were fitted to the annual peak flood data of three homogeneous regions. Using the L-moment ratios and the Z-statistic criteria, GEV distribution was identified as the most robust distribution among five candidate distributions for all the proposed sub-regions of the study area, and in general, it was concluded that the generalised extreme value distribution was the best-fit distribution for every three regions. The relative root mean square error (RRMSE) measure was applied for evaluating the performance of the index-flood and multiple-regression methods in comparison with the curve fitting (plotting position) method. In general, index-flood method gives more reliable estimations for various flood magnitudes of different recurrence intervals. Therefore, this method should be adopted as regional flood frequency method for the study area and the Namak-Lake basin

  10. Single-Camera-Based Method for Step Length Symmetry Measurement in Unconstrained Elderly Home Monitoring.

    Science.gov (United States)

    Cai, Xi; Han, Guang; Song, Xin; Wang, Jinkuan

    2017-11-01

    single-camera-based gait monitoring is unobtrusive, inexpensive, and easy-to-use to monitor daily gait of seniors in their homes. However, most studies require subjects to walk perpendicularly to camera's optical axis or along some specified routes, which limits its application in elderly home monitoring. To build unconstrained monitoring environments, we propose a method to measure step length symmetry ratio (a useful gait parameter representing gait symmetry without significant relationship with age) from unconstrained straight walking using a single camera, without strict restrictions on walking directions or routes. according to projective geometry theory, we first develop a calculation formula of step length ratio for the case of unconstrained straight-line walking. Then, to adapt to general cases, we propose to modify noncollinear footprints, and accordingly provide general procedure for step length ratio extraction from unconstrained straight walking. Our method achieves a mean absolute percentage error (MAPE) of 1.9547% for 15 subjects' normal and abnormal side-view gaits, and also obtains satisfactory MAPEs for non-side-view gaits (2.4026% for 45°-view gaits and 3.9721% for 30°-view gaits). The performance is much better than a well-established monocular gait measurement system suitable only for side-view gaits with a MAPE of 3.5538%. Independently of walking directions, our method can accurately estimate step length ratios from unconstrained straight walking. This demonstrates our method is applicable for elders' daily gait monitoring to provide valuable information for elderly health care, such as abnormal gait recognition, fall risk assessment, etc. single-camera-based gait monitoring is unobtrusive, inexpensive, and easy-to-use to monitor daily gait of seniors in their homes. However, most studies require subjects to walk perpendicularly to camera's optical axis or along some specified routes, which limits its application in elderly home monitoring

  11. A simple two-step method to fabricate highly transparent ITO/polymer nanocomposite films

    International Nuclear Information System (INIS)

    Liu, Haitao; Zeng, Xiaofei; Kong, Xiangrong; Bian, Shuguang; Chen, Jianfeng

    2012-01-01

    Highlights: ► A simple two-step method without further surface modification step was employed. ► ITO nanoparticles were easily to be uniformly dispersed in polymer matrix. ► ITO/polymer nanocomposite film had high transparency and UV/IR blocking properties. - Abstract: Transparent functional indium tin oxide (ITO)/polymer nanocomposite films were fabricated via a simple approach with two steps. Firstly, the functional monodisperse ITO nanoparticles were synthesized via a facile nonaqueous solvothermal method using bifunctional chemical agent (N-methyl-pyrrolidone, NMP) as the reaction solvent and surface modifier. Secondly, the ITO/acrylics polyurethane (PUA) nanocomposite films were fabricated by a simple sol-solution mixing method without any further surface modification step as often employed traditionally. Flower-like ITO nanoclusters with about 45 nm in diameter were mono-dispersed in ethyl acetate and each nanocluster was assembled by nearly spherical nanoparticles with primary size of 7–9 nm in diameter. The ITO nanoclusters exhibited an excellent dispersibility in polymer matrix of PUA, remaining their original size without any further agglomeration. When the loading content of ITO nanoclusters reached to 5 wt%, the transparent functional nanocomposite film featured a high transparency more than 85% in the visible light region (at 550 nm), meanwhile cutting off near-infrared radiation about 50% at 1500 nm and blocking UV ray about 45% at 350 nm. It could be potential for transparent functional coating materials applications.

  12. An empirical method to estimate bulk particulate refractive index for ocean satellite applications

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, T.; Desa, E.; Mascarenhas, A.A.M.Q.; Matondkar, S.G.P.; Naik, P.; Nayak, S.R.

    An empirical method is presented here to estimates bulk particulate refractive index using the measured inherent and apparent optical properties from the various waters types of the Arabian Sea. The empirical model, where the bulk refractive index...

  13. Procedures and methods that increase reliability and reproducibility of the transplanted kidney perfusion index

    International Nuclear Information System (INIS)

    Smokvina, A.

    1994-01-01

    At different times following surgery and during various complications, 119 studies were performed on 57 patients. In many patients studies were repeated several times. Twenty-three studies were performed in as many patients, in whom a normal function of the transplanted kidney was established by other diagnostic methods and retrospective analysis. Comparison was made of the perfusion index results obtained by the Hilson et al. method from 1978 and the ones obtained by my own modified method, which for calculating the index also takes into account: the time difference in appearance of the initial portions of the artery and kidney curves; the positioning of the region of interest over the distal part of the aorta; the bolus injection into the arteriovenous shunt of the forearm with high specific activity of small volumes of Tc-99m labelled agents; a fast 0.5 seconds study of data collection; and a standard for normalization of numerical data. The reliability of one or the other method tested by simulated time shift of the peak of arterial curves shows that the deviation percentage from the main index value in the unmodified method is 2-5 times greater than in the modified method. The normal value of the perfusion index applying the modified method is 91-171. (author)

  14. Malmquist Productivity Index by Extended VIKOR Method Using Interval Numbers

    OpenAIRE

    Fallah, Mohammad; Mohajeri, Amir; Najafi, Esmaeil

    2013-01-01

    The VIKOR method was developed for multicriteria optimization of complex systems. It determines the compromise ranking list and the compromise solution obtained with the given weights. This method focuses on ranking and selecting from a set of alternatives in the presence of conflicting criteria. Here, the VIKOR method is used for two times $t$ and $t+1$ . In order to calculate the progress or regression via Malmquist productivity index, the positive and negative ideals at ...

  15. An Improved Split-Step Wavelet Transform Method for Anomalous Radio Wave Propagation Modelling

    Directory of Open Access Journals (Sweden)

    A. Iqbal

    2014-12-01

    Full Text Available Anomalous tropospheric propagation caused by ducting phenomenon is a major problem in wireless communication. Thus, it is important to study the behavior of radio wave propagation in tropospheric ducts. The Parabolic Wave Equation (PWE method is considered most reliable to model anomalous radio wave propagation. In this work, an improved Split Step Wavelet transform Method (SSWM is presented to solve PWE for the modeling of tropospheric propagation over finite and infinite conductive surfaces. A large number of numerical experiments are carried out to validate the performance of the proposed algorithm. Developed algorithm is compared with previously published techniques; Wavelet Galerkin Method (WGM and Split-Step Fourier transform Method (SSFM. A very good agreement is found between SSWM and published techniques. It is also observed that the proposed algorithm is about 18 times faster than WGM and provide more details of propagation effects as compared to SSFM.

  16. Assessment of Heat Stress Index, and evaluation of theirvalidity in Mobarakeh Steel Association's Mobarakeh Steel Association's

    Directory of Open Access Journals (Sweden)

    M Sadeghi Aliabadi

    2005-10-01

    Full Text Available Background and Aims: Existence of heat in industries is considered as a serious problem. Someindexes have been invited to evaluate the rate of heat loud on worker. These indexes have beenused & comprised in different researches. This research validity of some of these indexes wasevaluated.Method: In purpose of evaluation of indexes and environmental factor ordinary and CataTermometer, WBCT Meter instrument and Humidity Meter was used. As a first step Molding unitdivided into 15 stations, and in the second step parameters measurement was begone . After thatthe obtained figures was used in special equation to calculate heat stress indexes.Mouth, skin, and core body temperature of 90 healthy and adopted male worker was recorded.Then the obtained result was analysed by Spss, and mean, standard deviation and correlationcoficient was ealeutated for each of them.Results: At first mean, minimum, maximum and standard deviation was calculated forenvironmental parameter and indexes.At the second step the relationship between personalfactors (mouth, skin and core body temperature and parameters and environmental indexes. (Airtemperature, radiation temperature, air velocity and relative humidity was assessed.The result showed no significance relationship between personal factor and heat stressor. Factor(p>5% only purse index had significance relationship (p=0/005, and the others indexes did notshowed significance relationship.Conclusion: In this research the relationship between purse and all variables was significance.Therefore this index considered as a first valid index in this research.WBGTindex shows the most relationship after the purse index in comparison with other indexes.Because of the other indexes's no significance relationship, so pours had a good validity in thisresearch.

  17. Constructing a Sophistication Index as a Method of Market ...

    African Journals Online (AJOL)

    This study investigates the process of index construction as a means of measuring a hypothetical construct that can typically not be measured by a single question or item and applying it as a method of market segmentation. The availability of incidental secondary data provided a relevant quantitative basis to illustrate this ...

  18. A Study of the Efficiency of Spatial Indexing Methods Applied to Large Astronomical Databases

    Science.gov (United States)

    Donaldson, Tom; Berriman, G. Bruce; Good, John; Shiao, Bernie

    2018-01-01

    Spatial indexing of astronomical databases generally uses quadrature methods, which partition the sky into cells used to create an index (usually a B-tree) written as database column. We report the results of a study to compare the performance of two common indexing methods, HTM and HEALPix, on Solaris and Windows database servers installed with a PostgreSQL database, and a Windows Server installed with MS SQL Server. The indexing was applied to the 2MASS All-Sky Catalog and to the Hubble Source catalog. On each server, the study compared indexing performance by submitting 1 million queries at each index level with random sky positions and random cone search radius, which was computed on a logarithmic scale between 1 arcsec and 1 degree, and measuring the time to complete the query and write the output. These simulated queries, intended to model realistic use patterns, were run in a uniform way on many combinations of indexing method and indexing level. The query times in all simulations are strongly I/O-bound and are linear with number of records returned for large numbers of sources. There are, however, considerable differences between simulations, which reveal that hardware I/O throughput is a more important factor in managing the performance of a DBMS than the choice of indexing scheme. The choice of index itself is relatively unimportant: for comparable index levels, the performance is consistent within the scatter of the timings. At small index levels (large cells; e.g. level 4; cell size 3.7 deg), there is large scatter in the timings because of wide variations in the number of sources found in the cells. At larger index levels, performance improves and scatter decreases, but the improvement at level 8 (14 min) and higher is masked to some extent in the timing scatter caused by the range of query sizes. At very high levels (20; 0.0004 arsec), the granularity of the cells becomes so high that a large number of extraneous empty cells begin to degrade

  19. Nonlinear Stability and Convergence of Two-Step Runge-Kutta Methods for Volterra Delay Integro-Differential Equations

    Directory of Open Access Journals (Sweden)

    Haiyan Yuan

    2013-01-01

    Full Text Available This paper introduces the stability and convergence of two-step Runge-Kutta methods with compound quadrature formula for solving nonlinear Volterra delay integro-differential equations. First, the definitions of (k,l-algebraically stable and asymptotically stable are introduced; then the asymptotical stability of a (k,l-algebraically stable two-step Runge-Kutta method with 0step Runge-Kutta method is algebraically stable and diagonally stable and its generalized stage order is p, then the method with compound quadrature formula is D-convergent of order at least min{p,ν}, where ν depends on the compound quadrature formula.

  20. Study on evaluation method for image quality of radiograph by step plate, (2)

    International Nuclear Information System (INIS)

    Terada, Yukihiro; Hirayama, Kazuo; Katoh, Mitsuaki.

    1992-01-01

    Recently, penetrameter sensitivity is used not only for the evaluation of radiographic image quality but also as a control method for examination conditions. However, it is necessary to take the parametric data for radiation quality in order to use it for the second purpose. The quantitative factor of radiation quality is determined by the absorption coefficient and the ratio of scattered radiation to transmitted radiation reaching the X-ray film. When the X-ray equipment changes in conducting the radiographic examination, these data must be measured in each case. This is a demerit in controlling examination conditions based on parametric data. As shown theoretically in the first report, the image quality value of a step plate which is defined by the density difference divided by film contrast and step plate thickness is useful to obtain the value of the radiation quality factor. This report deal with experimental investigation to measure it with the step plate. The result is showing that the value of the radiation quality factor calculated by the parametric data corresponded well with the image quality value measured by the step plate. Therefore, the convenient method to measure the value of the radiation quality factor has been established in order to control examination conditions in radiographic examination. (author)

  1. A simple three step method for selective placement of organic groups in mesoporous silica thin films

    Energy Technology Data Exchange (ETDEWEB)

    Franceschini, Esteban A. [Gerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica, Av. Gral Paz 1499 (B1650KNA) San Martín, Buenos Aires (Argentina); Llave, Ezequiel de la; Williams, Federico J. [Departamento de Química Inorgánica, Analítica y Química Física and INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, C1428EHA Buenos Aires (Argentina); Soler-Illia, Galo J.A.A., E-mail: galo.soler.illia@gmail.com [Departamento de Química Inorgánica, Analítica y Química Física and INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, C1428EHA Buenos Aires (Argentina); Instituto de Nanosistemas, Universidad Nacional de General San Martín, 25 de Mayo y Francia (1650) San Martín, Buenos Aires (Argentina)

    2016-02-01

    Selective functionalization of mesoporous silica thin films was achieved using a three step method. The first step consists in an outer surface functionalization, followed by washing off the structuring agent (second step), leaving the inner surface of the pores free to be functionalized in the third step. This reproducible method permits to anchor a volatile silane group in the outer film surface, and a second type of silane group in the inner surface of the pores. As a concept test we modified the outer surface of a mesoporous silica film with trimethylsilane (–Si–(CH{sub 3}){sub 3}) groups and the inner pore surface with propylamino (–Si–(CH{sub 2}){sub 3}–NH{sub 2}) groups. The obtained silica films were characterized by Environmental Ellipsometric Porosimetry (EEP), EDS, XPS, contact angle and electron microscopy. The selectively functionalized silica (SF) shows an amount of surface amino functions 4.3 times lower than the one-step functionalized (OSF) silica samples. The method presented here can be extended to a combination of silane chlorides and alkoxides as functional groups, opening up a new route toward the synthesis of multifunctional mesoporous thin films with precisely localized organic functions. - Highlights: • Selective functionalization of mesoporous silica thin films was achieved using a three step method. • A volatile silane group is anchored by evaporation on the outer film surface. • A second silane is deposited in the inner surface of the pores by post-grafting. • Contact angle, EDS and XPS measurements show different proportions of amino groups on both surfaces. • This method can be extended to a combination of silane chlorides and alkoxides functional groups.

  2. SYSTEMATIZATION OF THE BASIC STEPS OF THE STEP-AEROBICS

    Directory of Open Access Journals (Sweden)

    Darinka Korovljev

    2011-03-01

    Full Text Available Following the development of the powerful sport industry, in front of us appeared a lot of new opportunities for creating of the new programmes of exercising with certain requisites. One of such programmes is certainly step-aerobics. Step-aerobics can be defined as a type of aerobics consisting of the basic aerobic steps (basic steps applied in exercising on stepper (step bench, with a possibility to regulate its height. Step-aerobics itself can be divided into several groups, depending on the following: type of music, working methods and adopted knowledge of the attendants. In this work, the systematization of the basic steps in step-aerobics was made on the basis of the following criteria: steps origin, number of leg motions in stepping and relating the body support at the end of the step. Systematization of the basic steps of the step-aerobics is quite significant for making a concrete review of the existing basic steps, thus making creation of the step-aerobics lesson easier

  3. LiLEDDA: A Six-Step Forum-Based Netnographic Research Method for Nursing Science

    Directory of Open Access Journals (Sweden)

    MARTIN SALZMANN-ERIKSON

    2012-01-01

    Full Text Available Internet research methods in nursing science are less developed than in other sciences. We choose to present an approach to conducting nursing research on an internet-based forum. This paper presents LiLEDDA, a six-step forum-based netnographic research method for nursing science. The steps consist of: 1. Literature review and identification of the research question(s; 2. Locating the field(s online; 3. Ethical considerations; 4. Data gathering; 5. Data analysis and interpretation; and 6. Abstractions and trustworthiness. Traditional research approaches are limiting when studying non-normative and non-mainstream life-worlds and their cultures. We argue that it is timely to develop more up-to-date research methods and study designs applicable to nursing science that reflect social developments and human living conditions that tend to be increasingly online-based.

  4. Simultaneous reconstruction of 3D refractive index, temperature, and intensity distribution of combustion flame by double computed tomography technologies based on spatial phase-shifting method

    Science.gov (United States)

    Guo, Zhenyan; Song, Yang; Yuan, Qun; Wulan, Tuya; Chen, Lei

    2017-06-01

    In this paper, a transient multi-parameter three-dimensional (3D) reconstruction method is proposed to diagnose and visualize a combustion flow field. Emission and transmission tomography based on spatial phase-shifted technology are combined to reconstruct, simultaneously, the various physical parameter distributions of a propane flame. Two cameras triggered by the internal trigger mode capture the projection information of the emission and moiré tomography, respectively. A two-step spatial phase-shifting method is applied to extract the phase distribution in the moiré fringes. By using the filtered back-projection algorithm, we reconstruct the 3D refractive-index distribution of the combustion flow field. Finally, the 3D temperature distribution of the flame is obtained from the refractive index distribution using the Gladstone-Dale equation. Meanwhile, the 3D intensity distribution is reconstructed based on the radiation projections from the emission tomography. Therefore, the structure and edge information of the propane flame are well visualized.

  5. Index method for analyzing cost effectiveness of drilling rigs

    Energy Technology Data Exchange (ETDEWEB)

    Batura, N P; Bocharov, V V

    1978-01-01

    The method for a complete analysis of the factors determining cost effectiveness of a drilling rig fleet is examined. The system of calculating production indexes from statistical reports is relatively simple and is not difficult to use for production organizations. The analytical results may be used to develop actual measures used to increase cost effectiveness of drilling operations.

  6. The index-flood and the GRADEX methods combination for flood frequency analysis.

    Science.gov (United States)

    Fuentes, Diana; Di Baldassarre, Giuliano; Quesada, Beatriz; Xu, Chong-Yu; Halldin, Sven; Beven, Keith

    2017-04-01

    Flood frequency analysis is used in many applications, including flood risk management, design of hydraulic structures, and urban planning. However, such analysis requires of long series of observed discharge data which are often not available in many basins around the world. In this study, we tested the usefulness of combining regional discharge and local precipitation data to estimate the event flood volume frequency curve for 63 catchments in Mexico, Central America and the Caribbean. This was achieved by combining two existing flood frequency analysis methods, the regionalization index-flood approach with the GRADEX method. For up to 10-years return period, similar shape of the scaled flood frequency curve for catchments with similar flood behaviour was assumed from the index-flood approach. For return periods larger than 10-years the probability distribution of rainfall and discharge volumes were assumed to be asymptotically and exponential-type functions with the same scale parameter from the GRADEX method. Results showed that if the mean annual flood (MAF), used as index-flood, is known, the index-flood approach performed well for up to 10 years return periods, resulting in 25% mean relative error in prediction. For larger return periods the prediction capability decreased but could be improved by the use of the GRADEX method. As the MAF is unknown at ungauged and short-period measured basins, we tested predicting the MAF using catchments climate-physical characteristics, and discharge statistics, the latter when observations were available for only 8 years. Only the use of discharge statistics resulted in acceptable predictions.

  7. Aquifer sensitivity to pesticide leaching: Testing a soils and hydrogeologic index method

    Science.gov (United States)

    Mehnert, E.; Keefer, D.A.; Dey, W.S.; Wehrmann, H.A.; Wilson, S.D.; Ray, C.

    2005-01-01

    For years, researchers have sought index and other methods to predict aquifer sensitivity and vulnerability to nonpoint pesticide contamination. In 1995, an index method and map were developed to define aquifer sensitivity to pesticide leaching based on a combination of soil and hydrogeologic factors. The soil factor incorporated three soil properties: hydraulic conductivity, amount of organic matter within individual soil layers, and drainage class. These properties were obtained from a digital soil association map. The hydrogeologic factor was depth to uppermost aquifer material. To test this index method, a shallow ground water monitoring well network was designed, installed, and sampled in Illinois. The monitoring wells had a median depth of 7.6 m and were located adjacent to corn and soybean fields where the only known sources of pesticides were those used in normal agricultural production. From September 1998 through February 2001, 159 monitoring wells were sampled for 14 pesticides but no pesticide metabolites. Samples were collected and analyzed to assess the distribution of pesticide occurrence across three units of aquifer sensitivity. Pesticides were detected in 18% of all samples and nearly uniformly from samples from the three units of aquifer sensitivity. The new index method did not predict pesticide occurrence because occurrence was not dependent on the combined soil and hydrogeologic factors. However, pesticide occurrence was dependent on the tested hydrogeologic factor and was three times higher in areas where the depth to the uppermost aquifer was <6 m than in areas where the depth to the uppermost aquifer was 6 to <15 m. Copyright ?? 2005 National Ground Water Association.

  8. A signature-based method for indexing cell cycle phase distribution from microarray profiles

    Directory of Open Access Journals (Sweden)

    Mizuno Hideaki

    2009-03-01

    Full Text Available Abstract Background The cell cycle machinery interprets oncogenic signals and reflects the biology of cancers. To date, various methods for cell cycle phase estimation such as mitotic index, S phase fraction, and immunohistochemistry have provided valuable information on cancers (e.g. proliferation rate. However, those methods rely on one or few measurements and the scope of the information is limited. There is a need for more systematic cell cycle analysis methods. Results We developed a signature-based method for indexing cell cycle phase distribution from microarray profiles under consideration of cycling and non-cycling cells. A cell cycle signature masterset, composed of genes which express preferentially in cycling cells and in a cell cycle-regulated manner, was created to index the proportion of cycling cells in the sample. Cell cycle signature subsets, composed of genes whose expressions peak at specific stages of the cell cycle, were also created to index the proportion of cells in the corresponding stages. The method was validated using cell cycle datasets and quiescence-induced cell datasets. Analyses of a mouse tumor model dataset and human breast cancer datasets revealed variations in the proportion of cycling cells. When the influence of non-cycling cells was taken into account, "buried" cell cycle phase distributions were depicted that were oncogenic-event specific in the mouse tumor model dataset and were associated with patients' prognosis in the human breast cancer datasets. Conclusion The signature-based cell cycle analysis method presented in this report, would potentially be of value for cancer characterization and diagnostics.

  9. One-step method for the production of nanofluids

    Science.gov (United States)

    Kostic, Milivoje [Chicago, IL; Golubovic, Mihajlo [Chicago, IL; Hull, John R [Downers Grove, IL; Choi, Stephen U. S. [Napersville, IL

    2010-05-18

    A one step method and system for producing nanofluids by a particle-source evaporation and deposition of the evaporant into a base fluid. The base fluid such (i.e. ethylene glycol) is placed in a rotating cylindrical drum having an adjustable heater-boat-evaporator and heat exchanger-cooler apparatus. As the drum rotates, a thin liquid layer is formed on the inside surface of the drum. A heater-boat-evaporator having an evaporant material (particle-source) placed within its boat evaporator is adjustably positioned near a portion of the rotating thin liquid layer, the evaporant material being heated thereby evaporating a portion of the evaporant material, the evaporated material absorbed by the liquid film to form nanofluid.

  10. Rapid expansion method (REM) for time‐stepping in reverse time migration (RTM)

    KAUST Repository

    Pestana, Reynam C.

    2009-01-01

    We show that the wave equation solution using a conventional finite‐difference scheme, derived commonly by the Taylor series approach, can be derived directly from the rapid expansion method (REM). After some mathematical manipulation we consider an analytical approximation for the Bessel function where we assume that the time step is sufficiently small. From this derivation we find that if we consider only the first two Chebyshev polynomials terms in the rapid expansion method we can obtain the second order time finite‐difference scheme that is frequently used in more conventional finite‐difference implementations. We then show that if we use more terms from the REM we can obtain a more accurate time integration of the wave field. Consequently, we have demonstrated that the REM is more accurate than the usual finite‐difference schemes and it provides a wave equation solution which allows us to march in large time steps without numerical dispersion and is numerically stable. We illustrate the method with post and pre stack migration results.

  11. Novel two-step method to form silk fibroin fibrous hydrogel

    International Nuclear Information System (INIS)

    Ming, Jinfa; Li, Mengmeng; Han, Yuhui; Chen, Ying; Li, Han; Zuo, Baoqi; Pan, Fukui

    2016-01-01

    Hydrogels prepared by silk fibroin solution have been studied. However, mimicking the nanofibrous structures of extracellular matrix for fabricating biomaterials remains a challenge. Here, a novel two-step method was applied to prepare fibrous hydrogels using regenerated silk fibroin solution containing nanofibrils in a range of tens to hundreds of nanometers. When the gelation process of silk solution occurred, it showed a top-down type gel within 30 min. After gelation, silk fibroin fibrous hydrogels exhibited nanofiber network morphology with β-sheet structure. Moreover, the compressive stress and modulus of fibrous hydrogels were 31.9 ± 2.6 and 2.8 ± 0.8 kPa, respectively, which was formed using 2.0 wt.% concentration solutions. In addition, fibrous hydrogels supported BMSCs attachment and proliferation over 12 days. This study provides important insight in the in vitro processing of silk fibroin into useful new materials. - Highlights: • SF fibrous hydrogel was prepared by a novel two-step method. • SF solution containing nanofibrils in a range of tens to hundreds of nanometers was prepared. • Gelation process was top-down type gel with several minutes. • SF fibrous hydrogels exhibited nanofiber network morphology with β-sheet structure. • Fibrous hydrogels had higher compressive stresses superior to porous hydrogels.

  12. A hybrid spatio-temporal data indexing method for trajectory databases.

    Science.gov (United States)

    Ke, Shengnan; Gong, Jun; Li, Songnian; Zhu, Qing; Liu, Xintao; Zhang, Yeting

    2014-07-21

    In recent years, there has been tremendous growth in the field of indoor and outdoor positioning sensors continuously producing huge volumes of trajectory data that has been used in many fields such as location-based services or location intelligence. Trajectory data is massively increased and semantically complicated, which poses a great challenge on spatio-temporal data indexing. This paper proposes a spatio-temporal data indexing method, named HBSTR-tree, which is a hybrid index structure comprising spatio-temporal R-tree, B*-tree and Hash table. To improve the index generation efficiency, rather than directly inserting trajectory points, we group consecutive trajectory points as nodes according to their spatio-temporal semantics and then insert them into spatio-temporal R-tree as leaf nodes. Hash table is used to manage the latest leaf nodes to reduce the frequency of insertion. A new spatio-temporal interval criterion and a new node-choosing sub-algorithm are also proposed to optimize spatio-temporal R-tree structures. In addition, a B*-tree sub-index of leaf nodes is built to query the trajectories of targeted objects efficiently. Furthermore, a database storage scheme based on a NoSQL-type DBMS is also proposed for the purpose of cloud storage. Experimental results prove that HBSTR-tree outperforms TB*-tree in some aspects such as generation efficiency, query performance and query type.

  13. A Hybrid Spatio-Temporal Data Indexing Method for Trajectory Databases

    Directory of Open Access Journals (Sweden)

    Shengnan Ke

    2014-07-01

    Full Text Available In recent years, there has been tremendous growth in the field of indoor and outdoor positioning sensors continuously producing huge volumes of trajectory data that has been used in many fields such as location-based services or location intelligence. Trajectory data is massively increased and semantically complicated, which poses a great challenge on spatio-temporal data indexing. This paper proposes a spatio-temporal data indexing method, named HBSTR-tree, which is a hybrid index structure comprising spatio-temporal R-tree, B*-tree and Hash table. To improve the index generation efficiency, rather than directly inserting trajectory points, we group consecutive trajectory points as nodes according to their spatio-temporal semantics and then insert them into spatio-temporal R-tree as leaf nodes. Hash table is used to manage the latest leaf nodes to reduce the frequency of insertion. A new spatio-temporal interval criterion and a new node-choosing sub-algorithm are also proposed to optimize spatio-temporal R-tree structures. In addition, a B*-tree sub-index of leaf nodes is built to query the trajectories of targeted objects efficiently. Furthermore, a database storage scheme based on a NoSQL-type DBMS is also proposed for the purpose of cloud storage. Experimental results prove that HBSTR-tree outperforms TB*-tree in some aspects such as generation efficiency, query performance and query type.

  14. A Hybrid Spatio-Temporal Data Indexing Method for Trajectory Databases

    Science.gov (United States)

    Ke, Shengnan; Gong, Jun; Li, Songnian; Zhu, Qing; Liu, Xintao; Zhang, Yeting

    2014-01-01

    In recent years, there has been tremendous growth in the field of indoor and outdoor positioning sensors continuously producing huge volumes of trajectory data that has been used in many fields such as location-based services or location intelligence. Trajectory data is massively increased and semantically complicated, which poses a great challenge on spatio-temporal data indexing. This paper proposes a spatio-temporal data indexing method, named HBSTR-tree, which is a hybrid index structure comprising spatio-temporal R-tree, B*-tree and Hash table. To improve the index generation efficiency, rather than directly inserting trajectory points, we group consecutive trajectory points as nodes according to their spatio-temporal semantics and then insert them into spatio-temporal R-tree as leaf nodes. Hash table is used to manage the latest leaf nodes to reduce the frequency of insertion. A new spatio-temporal interval criterion and a new node-choosing sub-algorithm are also proposed to optimize spatio-temporal R-tree structures. In addition, a B*-tree sub-index of leaf nodes is built to query the trajectories of targeted objects efficiently. Furthermore, a database storage scheme based on a NoSQL-type DBMS is also proposed for the purpose of cloud storage. Experimental results prove that HBSTR-tree outperforms TB*-tree in some aspects such as generation efficiency, query performance and query type. PMID:25051028

  15. Development of the step complexity measure for emergency operating procedures using entropy concepts

    International Nuclear Information System (INIS)

    Park, Jinkyun; Jung, Wondea; Ha, Jaejoo

    2001-01-01

    For a nuclear power plant (NPP), symptom-based emergency operating procedures (EOPs) have been adopted to enhance the safety of NPPs through reduction of operators' workload under emergency conditions. Symptom-based EOPs, however, could place a workload on operators because they have to not only identify related symptoms, but also understand the context of steps that should be carried out. Therefore, many qualitative checklists are suggested to ensure the appropriateness of steps included in EOPs. However, since these qualitative evaluations have some drawbacks, a quantitative measure that can roughly estimate the complexity of EOP steps is imperative to compensate for them. In this paper, a method to evaluate the complexity of an EOP step is developed based on entropy measures that have been used in software engineering. Based on these, step complexity (SC) measure that can evaluate SC from various viewpoints (such as the amount of information/operators' actions included in each EOP step, and the logic structure of each EOP step) was developed. To verify the suitableness of the SC measure, estimated SC values are compared with subjective task load scores obtained from the NASA-TLX (task load index) method and step performance time obtained from a full scope simulator. From these comparisons, it was observed that estimated SC values generally agree with the NASA-TLX scores and step performance time data. Thus, it could be concluded that the developed SC measure would be considered for evaluating SC of an EOP step

  16. Evaluation of lung and chest wall mechanics during anaesthesia using the PEEP-step method.

    Science.gov (United States)

    Persson, P; Stenqvist, O; Lundin, S

    2018-04-01

    Postoperative pulmonary complications are common. Between patients there are differences in lung and chest wall mechanics. Individualised mechanical ventilation based on measurement of transpulmonary pressures would be a step forward. A previously described method evaluates lung and chest wall mechanics from a change of ΔPEEP and calculation of change in end-expiratory lung volume (ΔEELV). The aim of the present study was to validate this PEEP-step method (PSM) during general anaesthesia by comparing it with the conventional method using oesophageal pressure (PES) measurements. In 24 lung healthy subjects (BMI 18.5-32), three different sizes of PEEP steps were performed during general anaesthesia and ΔEELVs were calculated. Transpulmonary driving pressure (ΔPL) for a tidal volume equal to each ΔEELV was measured using PES measurements and compared to ΔPEEP with limits of agreement and intraclass correlation coefficients (ICC). ΔPL calculated with both methods was compared with a Bland-Altman plot. Mean differences between ΔPEEP and ΔPL were mechanical properties among the lung healthy patients stresses the need for individualised ventilator settings based on measurements of lung and chest wall mechanics. The agreement between ΔPLs measured by the two methods during general anaesthesia suggests the use of the non-invasive PSM in this patient population. NCT 02830516. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Rapid expansion method (REM) for time‐stepping in reverse time migration (RTM)

    KAUST Repository

    Pestana, Reynam C.; Stoffa, Paul L.

    2009-01-01

    an analytical approximation for the Bessel function where we assume that the time step is sufficiently small. From this derivation we find that if we consider only the first two Chebyshev polynomials terms in the rapid expansion method we can obtain the second

  18. Coupling of Spinosad Fermentation and Separation Process via Two-Step Macroporous Resin Adsorption Method.

    Science.gov (United States)

    Zhao, Fanglong; Zhang, Chuanbo; Yin, Jing; Shen, Yueqi; Lu, Wenyu

    2015-08-01

    In this paper, a two-step resin adsorption technology was investigated for spinosad production and separation as follows: the first step resin addition into the fermentor at early cultivation period to decrease the timely product concentration in the broth; the second step of resin addition was used after fermentation to adsorb and extract the spinosad. Based on this, a two-step macroporous resin adsorption-membrane separation process for spinosad fermentation, separation, and purification was established. Spinosad concentration in 5-L fermentor increased by 14.45 % after adding 50 g/L macroporous at the beginning of fermentation. The established two-step macroporous resin adsorption-membrane separation process got the 95.43 % purity and 87 % yield for spinosad, which were both higher than that of the conventional crystallization of spinosad from aqueous phase that were 93.23 and 79.15 % separately. The two-step macroporous resin adsorption method has not only carried out the coupling of spinosad fermentation and separation but also increased spinosad productivity. In addition, the two-step macroporous resin adsorption-membrane separation process performs better in spinosad yield and purity.

  19. Investigating the Effectiveness of Teaching Methods Based on a Four-Step Constructivist Strategy

    Science.gov (United States)

    Çalik, Muammer; Ayas, Alipaşa; Coll, Richard K.

    2010-02-01

    This paper reports on an investigation of the effectiveness an intervention using several different methods for teaching solution chemistry. The teaching strategy comprised a four-step approach derived from a constructivist view of learning. A sample consisting of 44 students (18 boys and 26 girls) was selected purposively from two different Grade 9 classes in the city of Trabzon, Turkey. Data collection employed a purpose-designed `solution chemistry concept test', consisting of 17 items, with the quantitative data from the survey supported by qualitative interview data. The findings suggest that using different methods embedded within the four-step constructivist-based teaching strategy enables students to refute some alternative conceptions, but does not completely eliminate student alternative conceptions for solution chemistry.

  20. A multi-step method with signal quality assessment and fine-tuning procedure to locate maternal and fetal QRS complexes from abdominal ECG recordings

    International Nuclear Information System (INIS)

    Liu, Chengyu; Li, Peng; Zhao, Lina; Di Maria, Costanzo; Zhang, Henggui; Chen, Zhiqing

    2014-01-01

    Non-invasive monitoring of fetal electrocardiogram (fECG) plays an important role in detecting and diagnosing fetal diseases. This study aimed to develop a multi-step method for locating both maternal and fetal QRS complexes from abdominal ECG (aECG) recordings. The proposed method included four major steps: abdominal ECG pre-processing, maternal QRS complex locating, maternal ECG cancellation and fetal QRS complex locating. Signal quality assessment (SQA) and fine-tuning for maternal ECG (FTM) were implemented in the first and third steps, respectively. The method was then evaluated using 75 non-invasive 4-channel aECG recordings provided by the PhysioNet/Computing in Cardiology Challenge 2013. The F 1 measure, which is a new index introduced by Behar et al (2013 Proc. Comput. Cardiol. 40 297–300), was used to assess the locating accuracy. The other two indices, mean squared error of heart rate (MSE H R) between the fetal HR signals estimated from the reference and our method (MSE H R in bpm 2 ) and root mean squared difference between the corresponding fetal RR intervals (MSE R R in ms) were also used to assess the locating accuracy. Overall, for the maternal QRS complex, the F 1 measure was 98.4% from the method without the implementation of SQA, and it was improved to 99.8% with SQA. For the fetal QRS complex, the F 1 measure, MSE H R and MSE R R were 84.9%, 185.6 bpm 2 and 19.4 ms for the method without both SQA and FTM procedures. They were improved to 93.9%, 47.5 bpm 2 and 7.6 ms with both SQA and FTM procedures. These improvements were observed from each individual subject. It can be concluded that implementing both SQA and FTM procedures could achieve better performance for locating both maternal and fetal QRS complexes. (paper)

  1. Cardiorespiratory endurance evaluation using heart rate analysis during ski simulator exercise and the Harvard step test in elementary school students.

    Science.gov (United States)

    Lee, Hyo Taek; Roh, Hyo Lyun; Kim, Yoon Sang

    2016-01-01

    [Purpose] Efficient management using exercise programs with various benefits should be provided by educational institutions for children in their growth phase. We analyzed the heart rates of children during ski simulator exercise and the Harvard step test to evaluate the cardiopulmonary endurance by calculating their post-exercise recovery rate. [Subjects and Methods] The subjects (n = 77) were categorized into a normal weight and an overweight/obesity group by body mass index. They performed each exercise for 3 minutes. The cardiorespiratory endurance was calculated using the Physical Efficiency Index formula. [Results] The ski simulator and Harvard step test showed that there was a significant difference in the heart rates of the 2 body mass index-based groups at each minute. The normal weight and the ski-simulator group had higher Physical Efficiency Index levels. [Conclusion] This study showed that a simulator exercise can produce a cumulative load even when performed at low intensity, and can be effectively utilized as exercise equipment since it resulted in higher Physical Efficiency Index levels than the Harvard step test. If schools can increase sport durability by stimulating students' interests, the ski simulator exercise can be used in programs designed to improve and strengthen students' physical fitness.

  2. Joint confidence region estimation for area under ROC curve and Youden index.

    Science.gov (United States)

    Yin, Jingjing; Tian, Lili

    2014-03-15

    In the field of diagnostic studies, the area under the ROC curve (AUC) serves as an overall measure of a biomarker/diagnostic test's accuracy. Youden index, defined as the overall correct classification rate minus one at the optimal cut-off point, is another popular index. For continuous biomarkers of binary disease status, although researchers mainly evaluate the diagnostic accuracy using AUC, for the purpose of making diagnosis, Youden index provides an important and direct measure of the diagnostic accuracy at the optimal threshold and hence should be taken into consideration in addition to AUC. Furthermore, AUC and Youden index are generally correlated. In this paper, we initiate the idea of evaluating diagnostic accuracy based on AUC and Youden index simultaneously. As the first step toward this direction, this paper only focuses on the confidence region estimation of AUC and Youden index for a single marker. We present both parametric and non-parametric approaches for estimating joint confidence region of AUC and Youden index. We carry out extensive simulation study to evaluate the performance of the proposed methods. In the end, we apply the proposed methods to a real data set. Copyright © 2013 John Wiley & Sons, Ltd.

  3. Development of environmental risk assessment framework using index method

    International Nuclear Information System (INIS)

    Ali, M.W.; Wu, Y.

    2000-01-01

    This paper presents a newly developed framework for assessing the risk from events which are considered to be major accidents to the environment according to the classifications by the United Kingdom Department of Environment (DoE). The application of an environmental risk assessment framework using the newly developed index method is demonstrated by means of a case study. The framework makes use of Environmental Hazard Index (EHI) method by the United Kingdom AEA Technology for releases to river, but improves it by taking account to toxic dose rather than concentration; taking account of long-term effects including persistence and bio accumulation, not just short term effects; extending the method to all aspects of environment, not just rivers; and allowing account to be taken of design changes to mitigate the risk. The development of the framework has also led to a revision of the tolerability criteria to be used with the framework proposed earlier by weakness and recommend further work to improve this newly proposed environmental risk assessment framework. From the study, it is recommended that the environmental risk assessment framework be applied to a wide range of other case studies in order to further improve it. The framework should be modified to maintain consistency when the DoE revises its definitions of major accidents to the environment. Ease-of-use of the framework (and any other environmental framework) would be aided by the compilation of databases for environmental toxicity, river data and available consequence models. Further work could also be done to suggest methods of mitigating the risk and including them as numerical factors within method. (author)

  4. Comparison on genomic predictions using GBLUP models and two single-step blending methods with different relationship matrices in the Nordic Holstein population

    DEFF Research Database (Denmark)

    Gao, Hongding; Christensen, Ole Fredslund; Madsen, Per

    2012-01-01

    Background A single-step blending approach allows genomic prediction using information of genotyped and non-genotyped animals simultaneously. However, the combined relationship matrix in a single-step method may need to be adjusted because marker-based and pedigree-based relationship matrices may...... not be on the same scale. The same may apply when a GBLUP model includes both genomic breeding values and residual polygenic effects. The objective of this study was to compare single-step blending methods and GBLUP methods with and without adjustment of the genomic relationship matrix for genomic prediction of 16......) a simple GBLUP method, 2) a GBLUP method with a polygenic effect, 3) an adjusted GBLUP method with a polygenic effect, 4) a single-step blending method, and 5) an adjusted single-step blending method. In the adjusted GBLUP and single-step methods, the genomic relationship matrix was adjusted...

  5. a Novel Approach of Indexing and Retrieving Spatial Polygons for Efficient Spatial Region Queries

    Science.gov (United States)

    Zhao, J. H.; Wang, X. Z.; Wang, F. Y.; Shen, Z. H.; Zhou, Y. C.; Wang, Y. L.

    2017-10-01

    Spatial region queries are more and more widely used in web-based applications. Mechanisms to provide efficient query processing over geospatial data are essential. However, due to the massive geospatial data volume, heavy geometric computation, and high access concurrency, it is difficult to get response in real time. Spatial indexes are usually used in this situation. In this paper, based on k-d tree, we introduce a distributed KD-Tree (DKD-Tree) suitbable for polygon data, and a two-step query algorithm. The spatial index construction is recursive and iterative, and the query is an in memory process. Both the index and query methods can be processed in parallel, and are implemented based on HDFS, Spark and Redis. Experiments on a large volume of Remote Sensing images metadata have been carried out, and the advantages of our method are investigated by comparing with spatial region queries executed on PostgreSQL and PostGIS. Results show that our approach not only greatly improves the efficiency of spatial region query, but also has good scalability, Moreover, the two-step spatial range query algorithm can also save cluster resources to support a large number of concurrent queries. Therefore, this method is very useful when building large geographic information systems.

  6. A NOVEL APPROACH OF INDEXING AND RETRIEVING SPATIAL POLYGONS FOR EFFICIENT SPATIAL REGION QUERIES

    Directory of Open Access Journals (Sweden)

    J. H. Zhao

    2017-10-01

    Full Text Available Spatial region queries are more and more widely used in web-based applications. Mechanisms to provide efficient query processing over geospatial data are essential. However, due to the massive geospatial data volume, heavy geometric computation, and high access concurrency, it is difficult to get response in real time. Spatial indexes are usually used in this situation. In this paper, based on k-d tree, we introduce a distributed KD-Tree (DKD-Tree suitbable for polygon data, and a two-step query algorithm. The spatial index construction is recursive and iterative, and the query is an in memory process. Both the index and query methods can be processed in parallel, and are implemented based on HDFS, Spark and Redis. Experiments on a large volume of Remote Sensing images metadata have been carried out, and the advantages of our method are investigated by comparing with spatial region queries executed on PostgreSQL and PostGIS. Results show that our approach not only greatly improves the efficiency of spatial region query, but also has good scalability, Moreover, the two-step spatial range query algorithm can also save cluster resources to support a large number of concurrent queries. Therefore, this method is very useful when building large geographic information systems.

  7. s-Step Krylov Subspace Methods as Bottom Solvers for Geometric Multigrid

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Samuel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lijewski, Mike [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Almgren, Ann [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Straalen, Brian Van [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Carson, Erin [Univ. of California, Berkeley, CA (United States); Knight, Nicholas [Univ. of California, Berkeley, CA (United States); Demmel, James [Univ. of California, Berkeley, CA (United States)

    2014-08-14

    Geometric multigrid solvers within adaptive mesh refinement (AMR) applications often reach a point where further coarsening of the grid becomes impractical as individual sub domain sizes approach unity. At this point the most common solution is to use a bottom solver, such as BiCGStab, to reduce the residual by a fixed factor at the coarsest level. Each iteration of BiCGStab requires multiple global reductions (MPI collectives). As the number of BiCGStab iterations required for convergence grows with problem size, and the time for each collective operation increases with machine scale, bottom solves in large-scale applications can constitute a significant fraction of the overall multigrid solve time. In this paper, we implement, evaluate, and optimize a communication-avoiding s-step formulation of BiCGStab (CABiCGStab for short) as a high-performance, distributed-memory bottom solver for geometric multigrid solvers. This is the first time s-step Krylov subspace methods have been leveraged to improve multigrid bottom solver performance. We use a synthetic benchmark for detailed analysis and integrate the best implementation into BoxLib in order to evaluate the benefit of a s-step Krylov subspace method on the multigrid solves found in the applications LMC and Nyx on up to 32,768 cores on the Cray XE6 at NERSC. Overall, we see bottom solver improvements of up to 4.2x on synthetic problems and up to 2.7x in real applications. This results in as much as a 1.5x improvement in solver performance in real applications.

  8. The Step Method - Battling Identity Theft Using E-Retailers' Websites

    Science.gov (United States)

    Schulze, Marion; Shah, Mahmood H.

    Identity theft is the fastest growing crime in the 21st century. This paper investigates firstly what well-known e-commerce organizations are communicating on their websites to address this issue. For this purpose we analyze secondary data (literature and websites of ten organizations). Secondly we investigate the good practice in this area and recommend practical steps. The key findings are that some organizations only publish minimum security information to comply with legal requirements. Others inform consumers on how they actively try to prevent identity theft, how consumers can protect themselves, and about supporting actions when identity theft related fraud actually happens. From these findings we developed the Support - Trust - Empowerment -Prevention (STEP) method. It is aimed at helping to prevent identity theft and dealing with consequences when it occurs. It can help organizations on gaining and keeping consumers’ trust which is so essential for e-retailers in a climate of rising fraud.

  9. A new four-step hierarchy method for combined assessment of groundwater quality and pollution.

    Science.gov (United States)

    Zhu, Henghua; Ren, Xiaohua; Liu, Zhizheng

    2017-12-28

    A new four-step hierarchy method was constructed and applied to evaluate the groundwater quality and pollution of the Dagujia River Basin. The assessment index system is divided into four types: field test indices, common inorganic chemical indices, inorganic toxicology indices, and trace organic indices. Background values of common inorganic chemical indices and inorganic toxicology indices were estimated with the cumulative-probability curve method, and the results showed that the background values of Mg 2+ (51.1 mg L -1 ), total hardness (TH) (509.4 mg L -1 ), and NO 3 - (182.4 mg L -1 ) are all higher than the corresponding grade III values of Quality Standard for Groundwater, indicating that they were poor indicators and therefore were not included in the groundwater quality assessment. The quality assessment results displayed that the field test indices were mainly classified as grade II, accounting for 60.87% of wells sampled. The indices of common inorganic chemical and inorganic toxicology were both mostly in the range of grade III, whereas the trace organic indices were predominantly classified as grade I. The variabilities and excess ratios of the indices were also calculated and evaluated. Spatial distributions showed that the groundwater with poor quality indices was mainly located in the northeast of the basin, which was well-connected with seawater intrusion. Additionally, the pollution assessment revealed that groundwater in well 44 was classified as "moderately polluted," wells 5 and 8 were "lightly polluted," and other wells were classified as "unpolluted."

  10. Mid-infrared supercontinuum generation in chalcogenide step-index fibers pumped at 2.9 and 4.5µm

    DEFF Research Database (Denmark)

    Kubat, Irnis; Agger, Christian; Møller, Uffe Visbech

    The Mid-InfraRed (MIR) spectral range (2-12µm) contains the spectral fingerprint of many organic molecules, which can be probed nondestructively for e.g. detection of skin cancer. For this SuperContinuum (SC) laser sources are good candidates since they can have broadband bandwidths together...... with high spectral densities. Here we consider a MIR SC laser sources based on chalcogenide step-index fibers with exceptionally high numerical aperture of ~1 pumped either with Er:ZBLAN and Pr:CHALC fiber laser operating at 2.9 and 4.5µm, respectively, having P0=1kW, T0=50ps, ν_R=4MHz and Pavg=200m......W. The optical properties of fibers (dispersion, nonlinearity and confinement loss) are modeled using the finite element tools based on measured refractive indices of the core and the cladding chalcogenide compositions. Generation of MIR SC is investigated using the Generalized Nonlinear Schrödinger Equation...

  11. Analyzing Multiple-Probe Microarray: Estimation and Application of Gene Expression Indexes

    KAUST Repository

    Maadooliat, Mehdi

    2012-07-26

    Gene expression index estimation is an essential step in analyzing multiple probe microarray data. Various modeling methods have been proposed in this area. Amidst all, a popular method proposed in Li and Wong (2001) is based on a multiplicative model, which is similar to the additive model discussed in Irizarry et al. (2003a) at the logarithm scale. Along this line, Hu et al. (2006) proposed data transformation to improve expression index estimation based on an ad hoc entropy criteria and naive grid search approach. In this work, we re-examined this problem using a new profile likelihood-based transformation estimation approach that is more statistically elegant and computationally efficient. We demonstrate the applicability of the proposed method using a benchmark Affymetrix U95A spiked-in experiment. Moreover, We introduced a new multivariate expression index and used the empirical study to shows its promise in terms of improving model fitting and power of detecting differential expression over the commonly used univariate expression index. As the other important content of the work, we discussed two generally encountered practical issues in application of gene expression index: normalization and summary statistic used for detecting differential expression. Our empirical study shows somewhat different findings from the MAQC project (MAQC, 2006).

  12. Shutdown Dose Rate Analysis Using the Multi-Step CADIS Method

    International Nuclear Information System (INIS)

    Ibrahim, Ahmad M.; Peplow, Douglas E.; Peterson, Joshua L.; Grove, Robert E.

    2015-01-01

    The Multi-Step Consistent Adjoint Driven Importance Sampling (MS-CADIS) hybrid Monte Carlo (MC)/deterministic radiation transport method was proposed to speed up the shutdown dose rate (SDDR) neutron MC calculation using an importance function that represents the neutron importance to the final SDDR. This work applied the MS-CADIS method to the ITER SDDR benchmark problem. The MS-CADIS method was also used to calculate the SDDR uncertainty resulting from uncertainties in the MC neutron calculation and to determine the degree of undersampling in SDDR calculations because of the limited ability of the MC method to tally detailed spatial and energy distributions. The analysis that used the ITER benchmark problem compared the efficiency of the MS-CADIS method to the traditional approach of using global MC variance reduction techniques for speeding up SDDR neutron MC calculation. Compared to the standard Forward-Weighted-CADIS (FW-CADIS) method, the MS-CADIS method increased the efficiency of the SDDR neutron MC calculation by 69%. The MS-CADIS method also increased the fraction of nonzero scoring mesh tally elements in the space-energy regions of high importance to the final SDDR

  13. Development of interface between MCNP-FISPACT-MCNP (IPR-MFM) based on rigorous two step method

    International Nuclear Information System (INIS)

    Shaw, A.K.; Swami, H.L.; Danani, C.

    2015-01-01

    In this work we present the development of interface tool between MCNP-FISPACT-MCNP (MFM) based on Rigorous Two Step method for the shutdown dose rate (SDDR) calculation. The MFM links MCNP radiation transport and the FISPACT inventory code through a suitable coupling scheme. MFM coupling scheme has three steps. In first step it picks neutron spectrum and total flux from MCNP output file to use as input parameter for FISPACT. It prepares the FISPACT input files by using irradiation history, neutron flux and neutron spectrum and then execute the FISPACT input file in the second step. Third step of MFM coupling scheme extracts the decay gammas from the FISPACT output file and prepares MCNP input file for decay gamma transport followed by execution of MCNP input file and estimation of SDDR. Here detailing of MFM methodology and flow scheme has been described. The programming language PYTHON has been chosen for this development of the coupling scheme. A complete loop of MCNP-FISPACT-MCNP has been developed to handle the simplified geometrical problems. For validation of MFM interface a manual cross-check has been performed which shows good agreements. The MFM interface also has been validated with exiting MCNP-D1S method for a simple geometry with 14 MeV cylindrical neutron source. (author)

  14. Study of CdTe quantum dots grown using a two-step annealing method

    Science.gov (United States)

    Sharma, Kriti; Pandey, Praveen K.; Nagpal, Swati; Bhatnagar, P. K.; Mathur, P. C.

    2006-02-01

    High size dispersion, large average radius of quantum dot and low-volume ratio has been a major hurdle in the development of quantum dot based devices. In the present paper, we have grown CdTe quantum dots in a borosilicate glass matrix using a two-step annealing method. Results of optical characterization and the theoretical model of absorption spectra have shown that quantum dots grown using two-step annealing have lower average radius, lesser size dispersion, higher volume ratio and higher decrease in bulk free energy as compared to quantum dots grown conventionally.

  15. Overweight, obesity, steps, and moderate to vigorous physical activity in children

    Directory of Open Access Journals (Sweden)

    Luis Carlos Oliveira

    Full Text Available ABSTRACT OBJECTIVE The objective of this study is to establish cutoff points for the number of steps/day and minutes/day of moderate to vigorous physical activity in relation to the risk of childhood overweight and obesity and their respective associations. In addition, we aim to identify the amount of steps/day needed to achieve the recommendation of moderate to vigorous physical activity in children from São Caetano do Sul. METHODS In total, 494 children have used an accelerometer to monitor steps/day and the intensity of physical activity (min/day. The moderate to vigorous physical activity has been categorized according to the public health recommendation (≤ 60 versus > 60 min/day. Overweight or obesity is defined as body mass index > +1 SD, based on reference data from the World Health Organization. The data on family income, education of parents, screen time, diet pattern, and sedentary time have been collected by questionnaires. Logistic regression and Receiver Operating Characteristic curves have been constructed. RESULTS On average, boys walked more steps/day (1,850 and performed more min/day of moderate to vigorous physical activity (23.1 than girls. Overall, 51.4% of the children have been classified as eutrophic and 48.6% as overweight or obese. Eutrophic boys walked 1,525 steps/day and performed 18.6 minutes/day more of moderate to vigorous physical activity than those with overweight/obesity (p 0.05. The cutoff points to prevent overweight and obesity in boys and girls were 10,500 and 8,500 steps/day and 66 and 46 min/day of moderate to vigorous physical activity, respectively. The walking of 9,700 steps/day for boys and 9,400 steps/day for girls ensures the scope of the recommendation of moderate to vigorous physical activity. CONCLUSIONS In boys, steps/day and moderate to vigorous physical activity have been negatively associated with body mass index, regardless of race, family income, education of parents, screen time, diet

  16. Microsoft® SQL Server® 2008 Step by Step

    CERN Document Server

    Hotek, Mike

    2009-01-01

    Teach yourself SQL Server 2008-one step at a time. Get the practical guidance you need to build database solutions that solve real-world business problems. Learn to integrate SQL Server data in your applications, write queries, develop reports, and employ powerful business intelligence systems.Discover how to:Install and work with core components and toolsCreate tables and index structuresManipulate and retrieve dataSecure, manage, back up, and recover databasesApply tuning plus optimization techniques to generate high-performing database applicationsOptimize availability through clustering, d

  17. Rising methods and leavening agents used in the production of bread do not impact the glycaemic index.

    Science.gov (United States)

    Fredensborg, Monica Hardman; Perry, Tracy; Mann, Jim; Chisholm, Alex; Rose, Meredith

    2010-01-01

    The aim of this study was to compare the glycaemic index of breads produced using different rising methods and leavening agents. Eleven bread varieties were selected based on method of production, and divided between three groups of ten participants (mean +/- SD age 30.0 +/- 10.7 years and BMI 22.9 +/- 2.8). Standard glycaemic index testing protocol was implemented after an overnight fast, using glucose as the reference food, and collecting blood samples over a two-hour period. Glycemic index was calculated using the usual method. Additionally, incremental area under the curve data were log transformed and glycaemic index was calculated using regression analysis. Mean glycaemic index values of the breads in ascending order were as follows: Swiss Rye; 60, Long oat; 68, Sourdough+oats; 71, Long rye; 76, Short oat; 77, Short whole meal; 78, Long whole meal; 80, Sourdough; 82, Short rye; 82, Yeast; 88, and Desem; 92. There were significant differences in mean glycaemic index values between Swiss Rye and Yeast (p = 0.010), Swiss Rye and Desem (p = 0.007) and Sourdough+oats and Desem (p = 0.043). The rising method and leavening agents used in this study did not impact on the glycaemic index of the breads tested. Other factors, such as increased bread density, and the addition of whole grains may be required to produce bread with a low glycaemic index.

  18. Multi-Index Stochastic Collocation (MISC) for random elliptic PDEs

    KAUST Repository

    Haji Ali, Abdul Lateef; Nobile, Fabio; Tamellini, Lorenzo; Tempone, Raul

    2016-01-01

    In this work we introduce the Multi-Index Stochastic Collocation method (MISC) for computing statistics of the solution of a PDE with random data. MISC is a combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. We propose an optimization procedure to select the most effective mixed differences to include in the MISC estimator: such optimization is a crucial step and allows us to build a method that, provided with sufficient solution regularity, is potentially more effective than other multi-level collocation methods already available in literature. We then provide a complexity analysis that assumes decay rates of product type for such mixed differences, showing that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one dimensional problem. We show the effectiveness of MISC with some computational tests, comparing it with other related methods available in the literature, such as the Multi-Index and Multilevel Monte Carlo, Multilevel Stochastic Collocation, Quasi Optimal Stochastic Collocation and Sparse Composite Collocation methods.

  19. Multi-Index Stochastic Collocation (MISC) for random elliptic PDEs

    KAUST Repository

    Haji Ali, Abdul Lateef

    2016-01-06

    In this work we introduce the Multi-Index Stochastic Collocation method (MISC) for computing statistics of the solution of a PDE with random data. MISC is a combination technique based on mixed differences of spatial approximations and quadratures over the space of random data. We propose an optimization procedure to select the most effective mixed differences to include in the MISC estimator: such optimization is a crucial step and allows us to build a method that, provided with sufficient solution regularity, is potentially more effective than other multi-level collocation methods already available in literature. We then provide a complexity analysis that assumes decay rates of product type for such mixed differences, showing that in the optimal case the convergence rate of MISC is only dictated by the convergence of the deterministic solver applied to a one dimensional problem. We show the effectiveness of MISC with some computational tests, comparing it with other related methods available in the literature, such as the Multi-Index and Multilevel Monte Carlo, Multilevel Stochastic Collocation, Quasi Optimal Stochastic Collocation and Sparse Composite Collocation methods.

  20. A simplified method for generation of pseudo natural colours from colour infrared aerial photos

    DEFF Research Database (Denmark)

    Knudsen, Thomas; Olsen, Brian Pilemann

    mapping methods. The method presented is a dramatic simplification of a recently published method, going from a 7 step to a 2 step procedure. The first step is a classification of the input image into 4 domains, based on simple thresholding of a vegetation index and a saturation measure for each pixel....... In the second step the blue colour component is estimated using tailored models for each domain. Green and red colour components are taken directly fron the CIR photo. The visual impression of the results from the 2 step method is only slightly inferior to the original 7 step method. The implementation, however...

  1. Search Method Based on Figurative Indexation of Folksonomic Features of Graphic Files

    Directory of Open Access Journals (Sweden)

    Oleg V. Bisikalo

    2013-11-01

    Full Text Available In this paper the search method based on usage of figurative indexation of folksonomic characteristics of graphical files is described. The method takes into account extralinguistic information, is based on using a model of figurative thinking of humans. The paper displays the creation of a method of searching image files based on their formal, including folksonomical clues.

  2. A Method of MPPT Control Based on Power Variable Step-size in Photovoltaic Converter System

    Directory of Open Access Journals (Sweden)

    Xu Hui-xiang

    2016-01-01

    Full Text Available Since the disadvantage of traditional MPPT algorithms of variable step-size, proposed power tracking based on variable step-size with the advantage method of the constant-voltage and the perturb-observe (P&O[1-3]. The control strategy modify the problem of voltage fluctuation caused by perturb-observe method, at the same time, introducing the advantage of constant-voltage method and simplify the circuit topology. With the theoretical derivation, control the output power of photovoltaic modules to change the duty cycle of main switch. Achieve the maximum power stabilization output, reduce the volatility of energy loss effectively, and improve the inversion efficiency[3,4]. Given the result of experimental test based theoretical derivation and the curve of MPPT when the prototype work.

  3. Testing of January Anomaly at ISE-100 Index with Power Ratio Method

    Directory of Open Access Journals (Sweden)

    Şule Yüksel Yiğiter

    2015-12-01

    Full Text Available AbstractNone of investors that can access all informations in the same ratio is not possible to earn higher returns according to Efficient Market Hypothesis. However, it has been set forth effect of time on returns in several studies and reached conflicting conclusions with hypothesis. In this context, one of the most important existing anomalies is also January month anomaly. In this study, it has been researched that if there is  January effect in BIST-100 index covering 2008-2014 period by using power ratio method. The presence of January month anomaly in BIST-100 index within specified period determined by analysis results.Keywords: Efficient Markets Hypothesis, January Month Anomaly, Power Ratio MethodJEL Classification Codes: G1,C22

  4. Research on the range side lobe suppression method for modulated stepped frequency radar signals

    Science.gov (United States)

    Liu, Yinkai; Shan, Tao; Feng, Yuan

    2018-05-01

    The magnitude of time-domain range sidelobe of modulated stepped frequency radar affects the imaging quality of inverse synthetic aperture radar (ISAR). In this paper, the cause of high sidelobe in modulated stepped frequency radar imaging is analyzed first in real environment. Then, the chaos particle swarm optimization (CPSO) is used to select the amplitude and phase compensation factors according to the minimum sidelobe criterion. Finally, the compensated one-dimensional range images are obtained. Experimental results show that the amplitude-phase compensation method based on CPSO algorithm can effectively reduce the sidelobe peak value of one-dimensional range images, which outperforms the common sidelobe suppression methods and avoids the coverage of weak scattering points by strong scattering points due to the high sidelobes.

  5. A two-step method for fast and reliable EUV mask metrology

    Science.gov (United States)

    Helfenstein, Patrick; Mochi, Iacopo; Rajendran, Rajeev; Yoshitake, Shusuke; Ekinci, Yasin

    2017-03-01

    One of the major obstacles towards the implementation of extreme ultraviolet lithography for upcoming technology nodes in semiconductor industry remains the realization of a fast and reliable detection methods patterned mask defects. We are developing a reflective EUV mask-scanning lensless imaging tool (RESCAN), installed at the Swiss Light Source synchrotron at the Paul Scherrer Institut. Our system is based on a two-step defect inspection method. In the first step, a low-resolution defect map is generated by die to die comparison of the diffraction patterns from areas with programmed defects, to those from areas that are known to be defect-free on our test sample. In a later stage, a die to database comparison will be implemented in which the measured diffraction patterns will be compared to those calculated directly from the mask layout. This Scattering Scanning Contrast Microscopy technique operates purely in the Fourier domain without the need to obtain the aerial image and, given a sufficient signal to noise ratio, defects are found in a fast and reliable way, albeit with a location accuracy limited by the spot size of the incident illumination. Having thus identified rough locations for the defects, a fine scan is carried out in the vicinity of these locations. Since our source delivers coherent illumination, we can use an iterative phase-retrieval method to reconstruct the aerial image of the scanned area with - in principle - diffraction-limited resolution without the need of an objective lens. Here, we will focus on the aerial image reconstruction technique and give a few examples to illustrate the capability of the method.

  6. Solving delay differential equations in S-ADAPT by method of steps.

    Science.gov (United States)

    Bauer, Robert J; Mo, Gary; Krzyzanski, Wojciech

    2013-09-01

    S-ADAPT is a version of the ADAPT program that contains additional simulation and optimization abilities such as parametric population analysis. S-ADAPT utilizes LSODA to solve ordinary differential equations (ODEs), an algorithm designed for large dimension non-stiff and stiff problems. However, S-ADAPT does not have a solver for delay differential equations (DDEs). Our objective was to implement in S-ADAPT a DDE solver using the methods of steps. The method of steps allows one to solve virtually any DDE system by transforming it to an ODE system. The solver was validated for scalar linear DDEs with one delay and bolus and infusion inputs for which explicit analytic solutions were derived. Solutions of nonlinear DDE problems coded in S-ADAPT were validated by comparing them with ones obtained by the MATLAB DDE solver dde23. The estimation of parameters was tested on the MATLB simulated population pharmacodynamics data. The comparison of S-ADAPT generated solutions for DDE problems with the explicit solutions as well as MATLAB produced solutions which agreed to at least 7 significant digits. The population parameter estimates from using importance sampling expectation-maximization in S-ADAPT agreed with ones used to generate the data. Published by Elsevier Ireland Ltd.

  7. One-step patterning of double tone high contrast and high refractive index inorganic spin-on resist

    Energy Technology Data Exchange (ETDEWEB)

    Zanchetta, E.; Della Giustina, G.; Brusatin, G. [Industrial Engineering Department and INSTM, Via Marzolo 9, 35131 Padova (Italy)

    2014-09-14

    A direct one-step and low temperature micro-fabrication process, enabling to realize large area totally inorganic TiO₂ micro-patterns from a spin-on resist, is presented. High refractive index structures (up to 2 at 632 nm) without the need for transfer processes have been obtained by mask assisted UV lithography, exploiting photocatalytic titania properties. A distinctive feature not shared by any of the known available resists and boosting the material versatility, is that the system behaves either as a positive or as negative tone resist, depending on the process parameters and on the development chemistry. In order to explain the resist double tone behavior, deep comprehension of the lithographic process parameters optimization and of the resist chemistry and structure evolution during the lithographic process, generally uncommon in literature, is reported. Another striking property of the presented resist is that the negative tone shows a high contrast up to 19, allowing to obtain structures resolution down to 2 μm wide. The presented process and material permit to directly fabricate different titania geometries of great importance for solar cells, photo-catalysis, and photonic crystals applications.

  8. Broadband mid-infrared supercontinuum generation in novel As2Se3-As2Se2 S step-index fibers

    Science.gov (United States)

    Wang, Yingying; Dai, Shixun; Han, Xin; Zhang, Peiqing; Liu, Yongxing; Wang, Xunsi; Sun, Shaochao

    2018-03-01

    We experimentally demonstrate the mid-infrared supercontinuum generation in a chalcogenide step-index fiber consisting of an As2Se3 core and an As2Se2 S cladding. The fiber with the core diameter of 21 μm was fabricated through the rod-in-tube technique and fiber-drawing process. The effect of pump wavelength, fiber length, and pump power on the spectral bandwidth and output power of the supercontinuum spectra generated from the fiber pumped by the ultrashort pulses of ∼ 150 fs with a repetition rate of 1000 Hz was systematically investigated. When pumping a 12-cm-long fiber at a wavelength of 6 . 5 μm with 14 mW pump laser power, a broadband supercontinuum spanning from 2 . 0 μm to 12 . 7 μm with an output power of 300 μW was obtained.

  9. The Value of Step-by-Step Risk Assessment for Unmanned Aircraft

    DEFF Research Database (Denmark)

    La Cour-Harbo, Anders

    2018-01-01

    The new European legislation expected in 2018 or 2019 will introduce a step-by-step process for conducting risk assessments for unmanned aircraft flight operations. This is a relatively simple approach to a very complex challenge. This work compares this step-by-step process to high fidelity risk...... modeling, and shows that at least for a series of example flight missions there is reasonable agreement between the two very different methods....

  10. Pyrosequencing™ : A one-step method for high resolution HLA typing

    Directory of Open Access Journals (Sweden)

    Marincola Francesco M

    2003-11-01

    Full Text Available Abstract While the use of high-resolution molecular typing in routine matching of human leukocyte antigens (HLA is expected to improve unrelated donor selection and transplant outcome, the genetic complexity of HLA still makes the current methodology limited and laborious. Pyrosequencing™ is a gel-free, sequencing-by-synthesis method. In a Pyrosequencing reaction, nucleotide incorporation proceeds sequentially along each DNA template at a given nucleotide dispensation order (NDO that is programmed into a pyrosequencer. Here we describe the design of a NDO that generates a pyrogram unique for any given allele or combination of alleles. We present examples of unique pyrograms generated from each of two heterozygous HLA templates, which would otherwise remain cis/trans ambiguous using standard sequencing based typing (SBT method. In addition, we display representative data that demonstrate long read and linear signal generation. These features are prerequisite of high-resolution typing and automated data analysis. In conclusion Pyrosequencing is a one-step method for high resolution DNA typing.

  11. Optimization of One-Step In Situ Transesterification Method for Accurate Quantification of EPA in Nannochloropsis gaditana

    Directory of Open Access Journals (Sweden)

    Yuting Tang

    2016-11-01

    Full Text Available Microalgae are a valuable source of lipid feedstocks for biodiesel and valuable omega-3 fatty acids. Nannochloropsis gaditana has emerged as a promising producer of eicosapentaenoic acid (EPA due to its fast growth rate and high EPA content. In the present study, the fatty acid profile of Nannochloropsis gaditana was found to be naturally high in EPA and devoid of docosahexaenoic acid (DHA, thereby providing an opportunity to maximize the efficacy of EPA production. Using an optimized one-step in situ transesterification method (methanol:biomass = 90 mL/g; HCl 5% by vol.; 70 °C; 1.5 h, the maximum fatty acid methyl ester (FAME yield of Nannochloropsis gaditana cultivated under rich condition was quantified as 10.04% ± 0.08% by weight with EPA-yields as high as 4.02% ± 0.17% based on dry biomass. The total FAME and EPA yields were 1.58- and 1.23-fold higher separately than that obtained using conventional two-step method (solvent system: methanol and chloroform. This one-step in situ method provides a fast and simple method to measure fatty acid methyl ester (FAME yields and could serve as a promising method to generate eicosapentaenoic acid methyl ester from microalgae.

  12. Variable Lifting Index (VLI): A New Method for Evaluating Variable Lifting Tasks.

    Science.gov (United States)

    Waters, Thomas; Occhipinti, Enrico; Colombini, Daniela; Alvarez-Casado, Enrique; Fox, Robert

    2016-08-01

    We seek to develop a new approach for analyzing the physical demands of highly variable lifting tasks through an adaptation of the Revised NIOSH (National Institute for Occupational Safety and Health) Lifting Equation (RNLE) into a Variable Lifting Index (VLI). There are many jobs that contain individual lifts that vary from lift to lift due to the task requirements. The NIOSH Lifting Equation is not suitable in its present form to analyze variable lifting tasks. In extending the prior work on the VLI, two procedures are presented to allow users to analyze variable lifting tasks. One approach involves the sampling of lifting tasks performed by a worker over a shift and the calculation of the Frequency Independent Lift Index (FILI) for each sampled lift and the aggregation of the FILI values into six categories. The Composite Lift Index (CLI) equation is used with lifting index (LI) category frequency data to calculate the VLI. The second approach employs a detailed systematic collection of lifting task data from production and/or organizational sources. The data are organized into simplified task parameter categories and further aggregated into six FILI categories, which also use the CLI equation to calculate the VLI. The two procedures will allow practitioners to systematically employ the VLI method to a variety of work situations where highly variable lifting tasks are performed. The scientific basis for the VLI procedure is similar to that for the CLI originally presented by NIOSH; however, the VLI method remains to be validated. The VLI method allows an analyst to assess highly variable manual lifting jobs in which the task characteristics vary from lift to lift during a shift. © 2015, Human Factors and Ergonomics Society.

  13. Imaginary Time Step Method to Solve the Dirac Equation with Nonlocal Potential

    International Nuclear Information System (INIS)

    Zhang Ying; Liang Haozhao; Meng Jie

    2009-01-01

    The imaginary time step (ITS) method is applied to solve the Dirac equation with nonlocal potentials in coordinate space. Taking the nucleus 12 C as an example, even with nonlocal potentials, the direct ITS evolution for the Dirac equation still meets the disaster of the Dirac sea. However, following the recipe in our former investigation, the disaster can be avoided by the ITS evolution for the corresponding Schroedinger-like equation without localization, which gives the convergent results exactly the same with those obtained iteratively by the shooting method with localized effective potentials.

  14. Accelerated solvent extraction method with one-step clean-up for hydrocarbons in soil

    International Nuclear Information System (INIS)

    Nurul Huda Mamat Ghani; Norashikin Sain; Rozita Osman; Zuraidah Abdullah Munir

    2007-01-01

    The application of accelerated solvent extraction (ASE) using hexane combined with neutral silica gel and sulfuric acid/ silica gel (SA/ SG) to remove impurities prior to analysis by gas chromatograph with flame ionization detector (GC-FID) was studied. The efficiency of extraction was evaluated based on the three hydrocarbons; dodecane, tetradecane and pentadecane spiked to soil sample. The effect of ASE operating conditions (extraction temperature, extraction pressure, static time) was evaluated and the optimized condition obtained from the study was extraction temperature of 160 degree Celsius, extraction pressure of 2000 psi with 5 minutes static extraction time. The developed ASE with one-step clean-up method was applied in the extraction of hydrocarbons from spiked soil and the amount extracted was comparable to ASE extraction without clean-up step with the advantage of obtaining cleaner extract with reduced interferences. Therefore in the developed method, extraction and clean-up for hydrocarbons in soil can be achieved rapidly and efficiently with reduced solvent usage. (author)

  15. A three operator split-step method covering a larger set of non-linear partial differential equations

    Science.gov (United States)

    Zia, Haider

    2017-06-01

    This paper describes an updated exponential Fourier based split-step method that can be applied to a greater class of partial differential equations than previous methods would allow. These equations arise in physics and engineering, a notable example being the generalized derivative non-linear Schrödinger equation that arises in non-linear optics with self-steepening terms. These differential equations feature terms that were previously inaccessible to model accurately with low computational resources. The new method maintains a 3rd order error even with these additional terms and models the equation in all three spatial dimensions and time. The class of non-linear differential equations that this method applies to is shown. The method is fully derived and implementation of the method in the split-step architecture is shown. This paper lays the mathematical ground work for an upcoming paper employing this method in white-light generation simulations in bulk material.

  16. On Merrifield-Simmons index of molecular graphs

    Directory of Open Access Journals (Sweden)

    Gutman Ivan

    2016-01-01

    Full Text Available The Merrifield-Simmons index σ = σ(G of a graph G is the number of independent vertex sets of G. This index can be calculated recursively and expressed in terms of Fibonacci numbers. We determine the molecular graphs for which σ can be recursively calculated in a single step.

  17. Method of determining effects of heat-induced irregular refractive index on an optical system.

    Science.gov (United States)

    Song, Xifa; Li, Lin; Huang, Yifan

    2015-09-01

    The effects of an irregular refractive index on optical performance are examined. A method was developed to express a lens's irregular refractive index distribution. An optical system and its mountings were modeled by a thermomechanical finite element (FE) program in the predicted operating temperature range, -45°C-50°C. FE outputs were elaborated using a MATLAB optimization routine; a nonlinear least squares algorithm was adopted to determine which gradient equation best fit each lens's refractive index distribution. The obtained gradient data were imported into Zemax for sequential ray-tracing analysis. The root mean square spot diameter, modulation transfer function, and diffraction ensquared energy were computed for an optical system under an irregular refractive index and under thermoelastic deformation. These properties are greatly reduced by the irregular refractive index effect, which is one-third to five-sevenths the size of the thermoelastic deformation effect. Thus, thermal analyses of optical systems should consider not only thermoelastic deformation but also refractive index irregularities caused by inhomogeneous temperature.

  18. 3D Model Retrieval Based on Vector Quantisation Index Histograms

    International Nuclear Information System (INIS)

    Lu, Z M; Luo, H; Pan, J S

    2006-01-01

    This paper proposes a novel technique to retrieval 3D mesh models using vector quantisation index histograms. Firstly, points are sampled uniformly on mesh surface. Secondly, to a point five features representing global and local properties are extracted. Thus feature vectors of points are obtained. Third, we select several models from each class, and employ their feature vectors as a training set. After training using LBG algorithm, a public codebook is constructed. Next, codeword index histograms of the query model and those in database are computed. The last step is to compute the distance between histograms of the query and those of the models in database. Experimental results show the effectiveness of our method

  19. Flu Diagnosis System Using Jaccard Index and Rough Set Approaches

    Science.gov (United States)

    Efendi, Riswan; Azah Samsudin, Noor; Mat Deris, Mustafa; Guan Ting, Yip

    2018-04-01

    Jaccard index and rough set approaches have been frequently implemented in decision support systems with various domain applications. Both approaches are appropriate to be considered for categorical data analysis. This paper presents the applications of sets operations for flu diagnosis systems based on two different approaches, such as, Jaccard index and rough set. These two different approaches are established using set operations concept, namely intersection and subset. The step-by-step procedure is demonstrated from each approach in diagnosing flu system. The similarity and dissimilarity indexes between conditional symptoms and decision are measured using Jaccard approach. Additionally, the rough set is used to build decision support rules. Moreover, the decision support rules are established using redundant data analysis and elimination of unclassified elements. A number data sets is considered to attempt the step-by-step procedure from each approach. The result has shown that rough set can be used to support Jaccard approaches in establishing decision support rules. Additionally, Jaccard index is better approach for investigating the worst condition of patients. While, the definitely and possibly patients with or without flu can be determined using rough set approach. The rules may improve the performance of medical diagnosis systems. Therefore, inexperienced doctors and patients are easier in preliminary flu diagnosis.

  20. Hybrid finite volume/ finite element method for radiative heat transfer in graded index media

    Science.gov (United States)

    Zhang, L.; Zhao, J. M.; Liu, L. H.; Wang, S. Y.

    2012-09-01

    The rays propagate along curved path determined by the Fermat principle in the graded index medium. The radiative transfer equation in graded index medium (GRTE) contains two specific redistribution terms (with partial derivatives to the angular coordinates) accounting for the effect of the curved ray path. In this paper, the hybrid finite volume with finite element method (hybrid FVM/FEM) (P.J. Coelho, J. Quant. Spectrosc. Radiat. Transf., vol. 93, pp. 89-101, 2005) is extended to solve the radiative heat transfer in two-dimensional absorbing-emitting-scattering graded index media, in which the spatial discretization is carried out using a FVM, while the angular discretization is by a FEM. The FEM angular discretization is demonstrated to be preferable in dealing with the redistribution terms in the GRTE. Two stiff matrix assembly schemes of the angular FEM discretization, namely, the traditional assembly approach and a new spherical assembly approach (assembly on the unit sphere of the solid angular space), are discussed. The spherical assembly scheme is demonstrated to give better results than the traditional assembly approach. The predicted heat flux distributions and temperature distributions in radiative equilibrium are determined by the proposed method and compared with the results available in other references. The proposed hybrid FVM/FEM method can predict the radiative heat transfer in absorbing-emitting-scattering graded index medium with good accuracy.

  1. Hybrid finite volume/ finite element method for radiative heat transfer in graded index media

    International Nuclear Information System (INIS)

    Zhang, L.; Zhao, J.M.; Liu, L.H.; Wang, S.Y.

    2012-01-01

    The rays propagate along curved path determined by the Fermat principle in the graded index medium. The radiative transfer equation in graded index medium (GRTE) contains two specific redistribution terms (with partial derivatives to the angular coordinates) accounting for the effect of the curved ray path. In this paper, the hybrid finite volume with finite element method (hybrid FVM/FEM) (P.J. Coelho, J. Quant. Spectrosc. Radiat. Transf., vol. 93, pp. 89-101, 2005) is extended to solve the radiative heat transfer in two-dimensional absorbing-emitting-scattering graded index media, in which the spatial discretization is carried out using a FVM, while the angular discretization is by a FEM. The FEM angular discretization is demonstrated to be preferable in dealing with the redistribution terms in the GRTE. Two stiff matrix assembly schemes of the angular FEM discretization, namely, the traditional assembly approach and a new spherical assembly approach (assembly on the unit sphere of the solid angular space), are discussed. The spherical assembly scheme is demonstrated to give better results than the traditional assembly approach. The predicted heat flux distributions and temperature distributions in radiative equilibrium are determined by the proposed method and compared with the results available in other references. The proposed hybrid FVM/FEM method can predict the radiative heat transfer in absorbing-emitting-scattering graded index medium with good accuracy.

  2. Development of a three dimensional circulation model based on fractional step method

    Directory of Open Access Journals (Sweden)

    Mazen Abualtayef

    2010-03-01

    Full Text Available A numerical model was developed for simulating a three-dimensional multilayer hydrodynamic and thermodynamic model in domains with irregular bottom topography. The model was designed for examining the interactions between flow and topography. The model was based on the three-dimensional Navier-Stokes equations and was solved using the fractional step method, which combines the finite difference method in the horizontal plane and the finite element method in the vertical plane. The numerical techniques were described and the model test and application were presented. For the model application to the northern part of Ariake Sea, the hydrodynamic and thermodynamic results were predicted. The numerically predicted amplitudes and phase angles were well consistent with the field observations.

  3. [Application of Delphi method in traditional Chinese medicine clinical research].

    Science.gov (United States)

    Bi, Ying-fei; Mao, Jing-yuan

    2012-03-01

    In recent years, Delphi method has been widely applied in traditional Chinese medicine (TCM) clinical research. This article analyzed the present application situation of Delphi method in TCM clinical research, and discussed some problems presented in the choice of evaluation method, classification of observation indexes and selection of survey items. On the basis of present application of Delphi method, the author analyzed the method on questionnaire making, selection of experts, evaluation of observation indexes and selection of survey items. Furthermore, the author summarized the steps of application of Delphi method in TCM clinical research.

  4. Acomparative Study Comparing Low-dose Step-up Versus Step-down in Polycystic Ovary Syndrome Resistant to Clomiphene

    Directory of Open Access Journals (Sweden)

    S Peivandi

    2010-03-01

    Full Text Available Introduction: Polycystic ovary syndrome(PCOS is one of the most common cause of infertility in women. clomiphene is the first line of treatment. however 20% of patients are resistant to clomiphene. because of follicular hypersensitivity to gonadotropins in pcod, multiple follicular growth and development occurs which is cause of OHSS and multiple pregnancy. Our aim of this random and clinical study was comparation between step-down and low dose step-up methods for induction ovulation in clomiphene resistant. Methods: 60 cases were included 30 women in low-dose step-up group and 30 women in step-down group. In low-dose step-up HMG 75u/d and in step-down HMG 225u/d was started on 3th days of cycle, monitoring with vaginal sonography was done on 8th days of cycle. When follicle with>14 mm in diameter was seen HMG dose was continued in low-dose step-up and was decreased in step-down group. When follicle reached to 18mm in diameter, amp HCG 10000 unit was injected and IUI was performed 36 hours later. Results: Number of HMG ampules, number of follicles> 14mm on the day of HCG injection and level of serum estradiol was greater in low dose step up protocol than step down protocol(p<0/0001. Ovulation rate and pregnancy rate was greater in lowdose step up group than step down group with significant difference (p<0/0001. Conclusion: Our study showed that low-dose step-up regimen with HMG is effective for stimulating ovulation and clinical pregnancy but in view of monofollicular growth, the step down method was more effective and safe. In our study multifolliular growth in step-up method was higher than step-down method. We can predict possibility of Ovarian Hyperstimulation Syndrome syndrome in highly sensitive PCOS patients.

  5. Influence of the drying method in chitosans purification step

    International Nuclear Information System (INIS)

    Fonseca, Ana C.M.; Batista, Jorge G.S.; Bettega, Antonio; Lima, Nelson B. de

    2015-01-01

    Currently, the study of extracellular biopolymers properties has received prominence for being easy extraction and purification. Chitosan has been an attractive proposition for applications in various fields such as engineering, biotechnology, medicine and pharmacology. For such applications, it is necessary purification of chitosan to obtain a product more concentrated and free of undesirable impurities. However, at this stage of the process of obtaining the biopolymer may occur morphological and physicochemical changes. This study evaluated the influence of the drying process after purification of a commercial chitosan sample and the importance of this step and its cost/benefit in applications requiring a high degree of purity. The method of drying influenced in the organoleptic properties and in the main characteristics of material. Analysis of the crystal structure by X-ray diffraction showed that the degree of crystallinity, X (%), in the purified chitosan samples was lower when compared with the unpurified sample. The degree of acetylation, DA (%), was analyzed by spectroscopy infrared with no significant changes on the three drying methods assessed, unlike the viscosimetric molecular weight, M_v, determined by capillary viscometry. (author)

  6. Influence of application methods of one-step self-etching adhesives on microtensile bond strength

    OpenAIRE

    Chul-Kyu Choi,; Sung-Ae Son; Jin-Hee Ha; Bock Hur; Hyeon-Cheol Kim; Yong-Hun Kwon; Jeong-Kil Park

    2011-01-01

    Objectives The purpose of this study was to evaluate the effect of various application methods of one-step self-etch adhesives to microtensile resin-dentin bond strength. Materials and Methods Thirty-six extracted human molars were used. The teeth were assigned randomly to twelve groups (n = 15), according to the three different adhesive systems (Clearfil Tri-S Bond, Adper Prompt L-Pop, G-Bond) and application methods. The adhesive systems were applied on the dentin as follows: 1) T...

  7. Baby-Friendly Hospital Initiative: evaluation of the Ten Steps to Successful Breastfeeding

    Directory of Open Access Journals (Sweden)

    Soraia da Silva Lopes

    2013-12-01

    Full Text Available OBJECTIVE: To asses the performance of the Ten Steps to Successful Breastfeeding in an university hospital. METHODS: Descriptive and quantitative research, in which 103 people were interviewed in the outpatient prenatal clinic, in the maternity-ward and in the Neonatal Intensive Care Unit of a university hospital in Vitória, Southeast Brazil. The "Institutional Self-Evaluation Questionnaire" of the Baby Friendly Hospital Initiative was applied. Using this tool, the outcome was measured by the concordance index (CI proposed by the World Health Organization and by the United Nations Children's Fund. RESULTS: Although the hospital does not have a policy that addresses promotion, protection and support for breastfeeding, 93.3% of the mothers had contact with their babies immediately after birth (step 4, 83.3% of the professionals guided mothers how to breastfeed (step 5, 86.6% of the neonates did not receive any food or drink other than breast milk (step 6, 100% of babies were housed together with their mothers (step 7, 83.3% of the women were encouraged for breastfeeding on demand (step 8 and 100% of the infants did not use bottles or pacifiers (step 9. CONCLUSIONS: 60% of the steps were completed by the hospital. The greatest difficulty was to inform pregnant women about the importance and the management of breastfeeding (step 3. Therefore, visits to pregnant women are recommended, in order to prepare them for breastfeeding and to explain about the infants' healthy feeding habits.

  8. [Optimization of one-step pelletization technology of Biqiu granules by Plackett-Burman design and Box-Behnken response surface methodology].

    Science.gov (United States)

    Zhang, Yan-jun; Liu, Li-li; Hu, Jun-hua; Wu, Yun; Chao, En-xiang; Xiao, Wei

    2015-11-01

    First with the qualified rate of granules as the evaluation index, significant influencing factors were firstly screened by Plackett-Burman design. Then, with the qualified rate and moisture content as the evaluation indexes, significant factors that affect one-step pelletization technology were further optimized by Box-Behnken design; experimental data were imitated by multiple regression and second-order polynomial equation; and response surface method was used for predictive analysis of optimal technology. The best conditions were as follows: inlet air temperature of 85 degrees C, sample introduction speed of 33 r x min(-1), density of concrete 1. 10. One-step pelletization technology of Biqiu granules by Plackett-Burman design and Box-Behnken response surface methodology was stable and feasible with good predictability, which provided reliable basis for the industrialized production of Biqiu granules.

  9. Mid-infrared supercontinuum generation to 12.5μm in large NA chalcogenide step-index fibres pumped at 4.5μm

    DEFF Research Database (Denmark)

    Kubat, Irnis; Agger, Christian; Møller, Uffe Visbech

    2014-01-01

    We present numerical modeling of mid-infrared (MIR) supercontinuum generation (SCG) in dispersion-optimized chalcogenide (CHALC) step-index fibres (SIFs) with exceptionally high numerical aperture (NA) around one, pumped with mode-locked praseodymium-doped (Pr3+) chalcogenide fibre lasers. The 4...... for the highest NA considered but required pumping at 4.7kW as well as up to 3m of fibre to compensate for the lower nonlinearities. The amount of power converted into the 8-10 μm band was 7.5 and 8.8mW for the 8 and 10μm fibres, respectively. For the 20μm core fibres up to 46mW was converted....

  10. Study of thermal annealing effect on Bragg gratings photo-inscribed in step-index polymer optical fibers

    Science.gov (United States)

    Hu, X.; Kinet, D.; Mégret, P.; Caucheteur, C.

    2016-04-01

    In this paper, both non-annealed and annealed trans-4-stilbenemethanol-doped step-index polymer optical fibers were photo-inscribed using a 325 nm HeCd laser with two different beam power densities reaching the fiber core. In the high density regime where 637 mW/mm2 are used, the grating reflectivity is stable over time after the photo-writing process but the reflected spectrum is of limited quality, as the grating physical length is limited to 1.2 mm. To produce longer gratings exhibiting more interesting spectral features, the beam is enlarged to 6 mm, decreasing the power density to 127 mW/mm2. In this second regime, the grating reflectivity is not stable after the inscription process but tends to decay for both kinds of fibers. A fortunate property in this case results from the possibility to fully recover the initial reflectivity using a post-inscription thermal annealing, where the gratings are annealed at 80 °C during 2 days. The observed evolutions for both regimes are attributed to the behavior of the excited intermediate states between the excited singlet and the ground singlet state of trans- and cis-isomers as well as the temperature-dependent glassy polymer matrix.

  11. Overlap relation between free-space Laguerre Gaussian modes and step-index fiber modes

    CSIR Research Space (South Africa)

    Bruning, R

    2015-09-01

    Full Text Available to control the optical proper- ties of the emerging beam or the excited field distributions at the fiber input. The simplest connection is given by fibers with an parabolic refractive index profile, typical of graded-index fibers, whose modes can be described..., in general free space modes are not suitable to excite selective pure fiber modes and additional beam shaping techniques are required, such as the use of computer generated holograms [5]. The main disadvan- tages of such beam shaping techniques are the low...

  12. A GPU-accelerated semi-implicit fractional-step method for numerical solutions of incompressible Navier-Stokes equations

    Science.gov (United States)

    Ha, Sanghyun; Park, Junshin; You, Donghyun

    2018-01-01

    Utility of the computational power of Graphics Processing Units (GPUs) is elaborated for solutions of incompressible Navier-Stokes equations which are integrated using a semi-implicit fractional-step method. The Alternating Direction Implicit (ADI) and the Fourier-transform-based direct solution methods used in the semi-implicit fractional-step method take advantage of multiple tridiagonal matrices whose inversion is known as the major bottleneck for acceleration on a typical multi-core machine. A novel implementation of the semi-implicit fractional-step method designed for GPU acceleration of the incompressible Navier-Stokes equations is presented. Aspects of the programing model of Compute Unified Device Architecture (CUDA), which are critical to the bandwidth-bound nature of the present method are discussed in detail. A data layout for efficient use of CUDA libraries is proposed for acceleration of tridiagonal matrix inversion and fast Fourier transform. OpenMP is employed for concurrent collection of turbulence statistics on a CPU while the Navier-Stokes equations are computed on a GPU. Performance of the present method using CUDA is assessed by comparing the speed of solving three tridiagonal matrices using ADI with the speed of solving one heptadiagonal matrix using a conjugate gradient method. An overall speedup of 20 times is achieved using a Tesla K40 GPU in comparison with a single-core Xeon E5-2660 v3 CPU in simulations of turbulent boundary-layer flow over a flat plate conducted on over 134 million grids. Enhanced performance of 48 times speedup is reached for the same problem using a Tesla P100 GPU.

  13. Radiation grafting of pH-sensitive acrylic acid and 4-vinyl pyridine onto nylon-6 using one- and two-step methods

    International Nuclear Information System (INIS)

    Ortega, Alejandra; Alarcón, Darío; Muñoz-Muñoz, Franklin; Garzón-Fontecha, Angélica; Burillo, Guillermina

    2015-01-01

    Acrylic acid (AAc) and 4-vinyl pyridine (4VP) were γ-ray grafted onto nylon-6 (Ny 6 ) films via pre-irradiation oxidative method. These monomers were grafted using a one-step method to render Ny 6 -g–(AAc/4VP). A two-step or sequential method was used to render (Ny 6 -g–AAc)-g–4VP. Random copolymer branches were obtained when the grafting was carried out via one-step method using the two monomers together. The two-step method was applied to graft chains of 4VP on both Ny 6 substrate and previously grafted AAc chains (Ny 6 -g–AAc). The two types of binary copolymers synthesized were characterized to determine the amount of grafted polymers, the thermal behavior (DSC and TGA), the surface composition (XPS), and the pH responsiveness. In the two-step process, it is possible to achieve a higher graft yield, better control of the amount of each monomer, good reversibility in the swelling/deswelling process and shorter time to achieve equilibrium swelling. - Highlights: • A new binary graft of 4VP and AAc onto Ny 6 films was synthesized by γ-radiation. • The binary grafted material has potential application for heavy ion retention. • The two-step method shows better conditions in swelling and reversibility properties. • Surface distribution of monomers was evaluate by XPS characterization

  14. Canine distemper virus detection by different methods of One-Step RT-qPCR

    Directory of Open Access Journals (Sweden)

    Claudia de Camargo Tozato

    2016-01-01

    Full Text Available ABSTRACT: Three commercial kits of One-Step RT-qPCR were evaluated for the molecular diagnosis of Canine Distemper Virus. Using the kit that showed better performance, two systems of Real-time RT-PCR (RT-qPCR assays were tested and compared for analytical sensitivity to Canine Distemper Virus RNA detection: a One-Step RT-qPCR (system A and a One-Step RT-qPCR combined with NESTED-qPCR (system B. Limits of detection for both systems were determined using a serial dilution of Canine Distemper Virus synthetic RNA or a positive urine sample. In addition, the same urine sample was tested using samples with prior centrifugation or ultracentrifugation. Commercial kits of One-Step RT-qPCR assays detected canine distemper virus RNA in 10 (100% urine samples from symptomatic animals tested. The One-Step RT-qPCR kit that showed better results was used to evaluate the analytical sensitivity of the A and B systems. Limit of detection using synthetic RNA for the system A was 11 RNA copies µL-1 and 110 RNA copies µl-1 for first round System B. The second round of the NESTED-qPCR for System B had a limit of detection of 11 copies µl-1. Relationship between Ct values and RNA concentration was linear. The RNA extracted from the urine dilutions was detected in dilutions of 10-3 and10-2 by System A and B respectively. Urine centrifugation increased the analytical sensitivity of the test and proved to be useful for routine diagnostics. The One-Step RT-qPCR is a fast, sensitive and specific method for canine distemper routine diagnosis and research projects that require sensitive and quantitative methodology.

  15. Three-step interferometric method with blind phase shifts by use of interframe correlation between interferograms

    Science.gov (United States)

    Muravsky, Leonid I.; Kmet', Arkady B.; Stasyshyn, Ihor V.; Voronyak, Taras I.; Bobitski, Yaroslav V.

    2018-06-01

    A new three-step interferometric method with blind phase shifts to retrieve phase maps (PMs) of smooth and low-roughness engineering surfaces is proposed. Evaluating of two unknown phase shifts is fulfilled by using the interframe correlation between interferograms. The method consists of two stages. The first stage provides recording of three interferograms of a test object and their processing including calculation of unknown phase shifts, and retrieval of a coarse PM. The second stage implements firstly separation of high-frequency and low-frequency PMs and secondly producing of a fine PM consisting of areal surface roughness and waviness PMs. Extraction of the areal surface roughness and waviness PMs is fulfilled by using a linear low-pass filter. The computer simulation and experiments fulfilled to retrieve a gauge block surface area and its areal surface roughness and waviness have confirmed the reliability of the proposed three-step method.

  16. Effect of One-Step and Multi-Steps Polishing System on Enamel Roughness

    Directory of Open Access Journals (Sweden)

    Cynthia Sumali

    2013-07-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 The final procedures of orthodontic treatment are bracket debonding and cleaning the remaining adhesive. Multi-step polishing system is the most common method used. The disadvantage of that system is long working time, because of the stages that should be done. Therefore, dental material manufacturer make an improvement to the system, to reduce several stages into one stage only. This new system is known as one-step polishing system. Objective: To compare the effect of one-step and multi-step polishing system on enamel roughness after orthodontic bracket debonding. Methods: Randomized control trial was conducted included twenty-eight maxillary premolar randomized into two polishing system; one-step OptraPol (Ivoclar, Vivadent and multi-step AstroPol (Ivoclar, Vivadent. After bracket debonding, the remaining adhesive on each group was cleaned by subjective polishing system for ninety seconds using low speed handpiece. The enamel roughness was subjected to profilometer, registering two roughness parameters (Ra, Rz. Independent t-test was used to analyze the mean score of enamel roughness in each group. Results: There was no significant difference of enamel roughness between one-step and multi-step polishing system (p>0.005. Conclusion: One-step polishing system can produce a similar enamel roughness to multi-step polishing system after bracket debonding and adhesive cleaning.DOI: 10.14693/jdi.v19i3.136

  17. Efficient protein structure search using indexing methods.

    Science.gov (United States)

    Kim, Sungchul; Sael, Lee; Yu, Hwanjo

    2013-01-01

    Understanding functions of proteins is one of the most important challenges in many studies of biological processes. The function of a protein can be predicted by analyzing the functions of structurally similar proteins, thus finding structurally similar proteins accurately and efficiently from a large set of proteins is crucial. A protein structure can be represented as a vector by 3D-Zernike Descriptor (3DZD) which compactly represents the surface shape of the protein tertiary structure. This simplified representation accelerates the searching process. However, computing the similarity of two protein structures is still computationally expensive, thus it is hard to efficiently process many simultaneous requests of structurally similar protein search. This paper proposes indexing techniques which substantially reduce the search time to find structurally similar proteins. In particular, we first exploit two indexing techniques, i.e., iDistance and iKernel, on the 3DZDs. After that, we extend the techniques to further improve the search speed for protein structures. The extended indexing techniques build and utilize an reduced index constructed from the first few attributes of 3DZDs of protein structures. To retrieve top-k similar structures, top-10 × k similar structures are first found using the reduced index, and top-k structures are selected among them. We also modify the indexing techniques to support θ-based nearest neighbor search, which returns data points less than θ to the query point. The results show that both iDistance and iKernel significantly enhance the searching speed. In top-k nearest neighbor search, the searching time is reduced 69.6%, 77%, 77.4% and 87.9%, respectively using iDistance, iKernel, the extended iDistance, and the extended iKernel. In θ-based nearest neighbor serach, the searching time is reduced 80%, 81%, 95.6% and 95.6% using iDistance, iKernel, the extended iDistance, and the extended iKernel, respectively.

  18. Clustering of financial time series with application to index and enhanced index tracking portfolio

    Science.gov (United States)

    Dose, Christian; Cincotti, Silvano

    2005-09-01

    A stochastic-optimization technique based on time series cluster analysis is described for index tracking and enhanced index tracking problems. Our methodology solves the problem in two steps, i.e., by first selecting a subset of stocks and then setting the weight of each stock as a result of an optimization process (asset allocation). Present formulation takes into account constraints on the number of stocks and on the fraction of capital invested in each of them, whilst not including transaction costs. Computational results based on clustering selection are compared to those of random techniques and show the importance of clustering in noise reduction and robust forecasting applications, in particular for enhanced index tracking.

  19. High accuracy step gauge interferometer

    Science.gov (United States)

    Byman, V.; Jaakkola, T.; Palosuo, I.; Lassila, A.

    2018-05-01

    Step gauges are convenient transfer standards for the calibration of coordinate measuring machines. A novel interferometer for step gauge calibrations implemented at VTT MIKES is described. The four-pass interferometer follows Abbe’s principle and measures the position of the inductive probe attached to a measuring head. The measuring head of the instrument is connected to a balanced boom above the carriage by a piezo translation stage. A key part of the measuring head is an invar structure on which the inductive probe and the corner cubes of the measuring arm of the interferometer are attached. The invar structure can be elevated so that the probe is raised without breaking the laser beam. During probing, the bending of the probe and the interferometer readings are recorded and the measurement face position is extrapolated to zero force. The measurement process is fully automated and the face positions of the steps can be measured up to a length of 2 m. Ambient conditions are measured continuously and the refractive index of air is compensated for. Before measurements the step gauge is aligned with an integrated 2D coordinate measuring system. The expanded uncertainty of step gauge calibration is U=\\sqrt{{{(64 nm)}2}+{{(88× {{10}-9}L)}2}} .

  20. Sharp Penalty Term and Time Step Bounds for the Interior Penalty Discontinuous Galerkin Method for Linear Hyperbolic Problems

    NARCIS (Netherlands)

    Geevers, Sjoerd; van der Vegt, J.J.W.

    2017-01-01

    We present sharp and sucient bounds for the interior penalty term and time step size to ensure stability of the symmetric interior penalty discontinuous Galerkin (SIPDG) method combined with an explicit time-stepping scheme. These conditions hold for generic meshes, including unstructured

  1. A Novel Motion Compensation Method for Random Stepped Frequency Radar with M-sequence

    Science.gov (United States)

    Liao, Zhikun; Hu, Jiemin; Lu, Dawei; Zhang, Jun

    2018-01-01

    The random stepped frequency radar is a new kind of synthetic wideband radar. In the research, it has been found that it possesses a thumbtack-like ambiguity function which is considered to be the ideal one. This also means that only a precise motion compensation could result in the correct high resolution range profile. In this paper, we will introduce the random stepped frequency radar coded by M-sequence firstly and briefly analyse the effect of relative motion between target and radar on the distance imaging, which is called defocusing problem. Then, a novel motion compensation method, named complementary code cancellation, will be put forward to solve this problem. Finally, the simulated experiments will demonstrate its validity and the computational analysis will show up its efficiency.

  2. Large-area gold nanohole arrays fabricated by one-step method for surface plasmon resonance biochemical sensing.

    Science.gov (United States)

    Qi, Huijie; Niu, Lihong; Zhang, Jie; Chen, Jian; Wang, Shujie; Yang, Jingjing; Guo, Siyi; Lawson, Tom; Shi, Bingyang; Song, Chunpeng

    2018-04-01

    Surface plasmon resonance (SPR) nanosensors based on metallic nanohole arrays have been widely reported to detect binding interactions in biological specimens. A simple and effective method for constructing nanoscale arrays is essential for the development of SPR nanosensors. In this work, we report a one-step method to fabricate nanohole arrays by thermal nanoimprinting in the matrix of IPS (Intermediate Polymer Stamp). No additional etching process or supporting substrate is required. The preparation process is simple, time-saving and compatible for roll-to-roll process, potentially allowing mass production. Moreover, the nanohole arrays were integrated into detection platform as SPR sensors to investigate different types of biological binding interactions. The results demonstrate that our one-step method can be used to efficiently fabricate large-area and uniform nanohole arrays for biochemical sensing.

  3. On the limitations of fixed-step-size adaptive methods with response confidence.

    Science.gov (United States)

    Hsu, Yung-Fong; Chin, Ching-Lan

    2014-05-01

    The family of (non-parametric, fixed-step-size) adaptive methods, also known as 'up-down' or 'staircase' methods, has been used extensively in psychophysical studies for threshold estimation. Extensions of adaptive methods to non-binary responses have also been proposed. An example is the three-category weighted up-down (WUD) method (Kaernbach, 2001) and its four-category extension (Klein, 2001). Such an extension, however, is somewhat restricted, and in this paper we discuss its limitations. To facilitate the discussion, we characterize the extension of WUD by an algorithm that incorporates response confidence into a family of adaptive methods. This algorithm can also be applied to two other adaptive methods, namely Derman's up-down method and the biased-coin design, which are suitable for estimating any threshold quantiles. We then discuss via simulations of the above three methods the limitations of the algorithm. To illustrate, we conduct a small scale of experiment using the extended WUD under different response confidence formats to evaluate the consistency of threshold estimation. © 2013 The British Psychological Society.

  4. Characterization of Fabricated Photonic Crystal Fibers Using Effective Index Method

    OpenAIRE

    Faramarz E. Seraji

    2009-01-01

    In this paper, the characteristics of photonic crystal fibers (PCFs), which have been experimentally determined in the last few years in Iran's Telecom Research Center are analyzed and compared theoretically using an effective index method. The PCFs under investigation are fabricated with a high speed drawing process that has not yet been reported elsewhere. It was shown that at higher wavelengths in PCFs; the light field is confined in the core where in shorter wavelengths the field spread...

  5. One-Step Method for Preparation of Magnetic Nanoparticles Coated with Chitosan

    Directory of Open Access Journals (Sweden)

    Karla M. Gregorio-Jauregui

    2012-01-01

    Full Text Available Preparation of magnetic nanoparticles coated with chitosan in one step by the coprecipitation method in the presence of different chitosan concentrations is reported here. Obtaining of magnetic superparamagnetic nanoparticles was confirmed by X-ray diffraction and magnetic measurements. Scanning transmission electron microscopy allowed to identify spheroidal nanoparticles with around 10-11 nm in average diameter. Characterization of the products by Fourier transform infrared spectroscopy demonstrated that composite chitosan-magnetic nanoparticles were obtained. Chitosan content in obtained nanocomposites was estimated by thermogravimetric analysis. The nanocomposites were tested in Pb2+ removal from a PbCl2 aqueous solution, showing a removal efficacy up to 53.6%. This work provides a simple method for chitosan-coated nanoparticles obtaining, which could be useful for heavy metal ions removal from water.

  6. Accuracy of Single-Step versus 2-Step Double-Mix Impression Technique

    DEFF Research Database (Denmark)

    Franco, Eduardo Batista; da Cunha, Leonardo Fernandes; Herrera, Francyle Simões

    2011-01-01

    Objective. To investigate the accuracy of dies obtained from single-step and 2-step double-mix impressions. Material and Methods. Impressions (n = 10) of a stainless steel die simulating a complete crown preparation were performed using a polyether (Impregum Soft Heavy and Light body) and a vinyl...

  7. Quality Index Method - An objective tool for determination of sensory quality

    DEFF Research Database (Denmark)

    Hyldig, Grethe; Green-Petersen, Ditte

    2004-01-01

    Sensory evaluation is one of the most important methods for assessing freshness and quality in the fish sector and in fish-inspection services. Sensory methods performed in a proper way are a rapid and accurate tool providing unique information about food. Traditionally, sensory methods have been...... seen as a subjective assessment of quality. However, sensory methods can be turned into an objective tool. European fisheries research institutes have developed such a tool, by which sensory assessment is performed in a systematic way with an objective quality assessment method called the Quality Index...... Method (QIM). It is foreseen that the QIM will be useful to give feedback to fishermen concerning the quality of their catch, which may in turn influence better handling on board. The QIM is a promising method for quick and reliable assessment of the freshness of fish. It is expected to become...

  8. A two-stage method for inverse medium scattering

    KAUST Repository

    Ito, Kazufumi; Jin, Bangti; Zou, Jun

    2013-01-01

    We present a novel numerical method to the time-harmonic inverse medium scattering problem of recovering the refractive index from noisy near-field scattered data. The approach consists of two stages, one pruning step of detecting the scatterer

  9. Rapid one-step selection method for generating nucleic acid aptamers: development of a DNA aptamer against α-bungarotoxin.

    Directory of Open Access Journals (Sweden)

    Lasse H Lauridsen

    Full Text Available BACKGROUND: Nucleic acids based therapeutic approaches have gained significant interest in recent years towards the development of therapeutics against many diseases. Recently, research on aptamers led to the marketing of Macugen®, an inhibitor of vascular endothelial growth factor (VEGF for the treatment of age related macular degeneration (AMD. Aptamer technology may prove useful as a therapeutic alternative against an array of human maladies. Considering the increased interest in aptamer technology globally that rival antibody mediated therapeutic approaches, a simplified selection, possibly in one-step, technique is required for developing aptamers in limited time period. PRINCIPAL FINDINGS: Herein, we present a simple one-step selection of DNA aptamers against α-bungarotoxin. A toxin immobilized glass coverslip was subjected to nucleic acid pool binding and extensive washing followed by PCR enrichment of the selected aptamers. One round of selection successfully identified a DNA aptamer sequence with a binding affinity of 7.58 µM. CONCLUSION: We have demonstrated a one-step method for rapid production of nucleic acid aptamers. Although the reported binding affinity is in the low micromolar range, we believe that this could be further improved by using larger targets, increasing the stringency of selection and also by combining a capillary electrophoresis separation prior to the one-step selection. Furthermore, the method presented here is a user-friendly, cheap and an easy way of deriving an aptamer unlike the time consuming conventional SELEX-based approach. The most important application of this method is that chemically-modified nucleic acid libraries can also be used for aptamer selection as it requires only one enzymatic step. This method could equally be suitable for developing RNA aptamers.

  10. Selective adsorption of a supramolecular structure on flat and stepped gold surfaces

    Science.gov (United States)

    Peköz, Rengin; Donadio, Davide

    2018-04-01

    Halogenated aromatic molecules assemble on surfaces forming both hydrogen and halogen bonds. Even though these systems have been intensively studied on flat metal surfaces, high-index vicinal surfaces remain challenging, as they may induce complex adsorbate structures. The adsorption of 2,6-dibromoanthraquinone (2,6-DBAQ) on flat and stepped gold surfaces is studied by means of van der Waals corrected density functional theory. Equilibrium geometries and corresponding adsorption energies are systematically investigated for various different adsorption configurations. It is shown that bridge sites and step edges are the preferred adsorption sites for single molecules on flat and stepped surfaces, respectively. The role of van der Waals interactions, halogen bonds and hydrogen bonds are explored for a monolayer coverage of 2,6-DBAQ molecules, revealing that molecular flexibility and intermolecular interactions stabilize two-dimensional networks on both flat and stepped surfaces. Our results provide a rationale for experimental observation of molecular carpeting on high-index vicinal surfaces of transition metals.

  11. Two-step reconstruction method using global optimization and conjugate gradient for ultrasound-guided diffuse optical tomography.

    Science.gov (United States)

    Tavakoli, Behnoosh; Zhu, Quing

    2013-01-01

    Ultrasound-guided diffuse optical tomography (DOT) is a promising method for characterizing malignant and benign lesions in the female breast. We introduce a new two-step algorithm for DOT inversion in which the optical parameters are estimated with the global optimization method, genetic algorithm. The estimation result is applied as an initial guess to the conjugate gradient (CG) optimization method to obtain the absorption and scattering distributions simultaneously. Simulations and phantom experiments have shown that the maximum absorption and reduced scattering coefficients are reconstructed with less than 10% and 25% errors, respectively. This is in contrast with the CG method alone, which generates about 20% error for the absorption coefficient and does not accurately recover the scattering distribution. A new measure of scattering contrast has been introduced to characterize benign and malignant breast lesions. The results of 16 clinical cases reconstructed with the two-step method demonstrates that, on average, the absorption coefficient and scattering contrast of malignant lesions are about 1.8 and 3.32 times higher than the benign cases, respectively.

  12. Stepping to the Beat: Feasibility and Potential Efficacy of a Home-Based Auditory-Cued Step Training Program in Chronic Stroke

    Directory of Open Access Journals (Sweden)

    Rachel L. Wright

    2017-08-01

    Full Text Available BackgroundHemiparesis after stroke typically results in a reduced walking speed, an asymmetrical gait pattern and a reduced ability to make gait adjustments. The purpose of this pilot study was to investigate the feasibility and preliminary efficacy of home-based training involving auditory cueing of stepping in place.MethodsTwelve community-dwelling participants with chronic hemiparesis completed two 3-week blocks of home-based stepping to music overlaid with an auditory metronome. Tempo of the metronome was increased 5% each week. One 3-week block used a regular metronome, whereas the other 3-week block had phase shift perturbations randomly inserted to cue stepping adjustments.ResultsAll participants reported that they enjoyed training, with 75% completing all training blocks. No adverse events were reported. Walking speed, Timed Up and Go (TUG time and Dynamic Gait Index (DGI scores (median [inter-quartile range] significantly improved between baseline (speed = 0.61 [0.32, 0.85] m⋅s−1; TUG = 20.0 [16.0, 39.9] s; DGI = 14.5 [11.3, 15.8] and post stepping training (speed = 0.76 [0.39, 1.03] m⋅s−1; TUG = 16.3 [13.3, 35.1] s; DGI = 16.0 [14.0, 19.0] and was maintained at follow-up (speed = 0.75 [0.41, 1.03] m⋅s−1; TUG = 16.5 [12.9, 34.1] s; DGI = 16.5 [13.5, 19.8].ConclusionThis pilot study suggests that auditory-cued stepping conducted at home was feasible and well-tolerated by participants post-stroke, with improvements in walking and functional mobility. No differences were detected between regular and phase-shift training with the metronome at each assessment point.

  13. High-resolution wave-theory-based ultrasound reflection imaging using the split-step fourier and globally optimized fourier finite-difference methods

    Science.gov (United States)

    Huang, Lianjie

    2013-10-29

    Methods for enhancing ultrasonic reflection imaging are taught utilizing a split-step Fourier propagator in which the reconstruction is based on recursive inward continuation of ultrasonic wavefields in the frequency-space and frequency-wave number domains. The inward continuation within each extrapolation interval consists of two steps. In the first step, a phase-shift term is applied to the data in the frequency-wave number domain for propagation in a reference medium. The second step consists of applying another phase-shift term to data in the frequency-space domain to approximately compensate for ultrasonic scattering effects of heterogeneities within the tissue being imaged (e.g., breast tissue). Results from various data input to the method indicate significant improvements are provided in both image quality and resolution.

  14. An autostratigraphic view of the long-term dynamics of delta distributary channels: A new step forward with the grade index model

    Science.gov (United States)

    Naruse, H.; Muto, T.

    2017-12-01

    Autostratigraphy is the stratigraphy that is generated by large-scale, deterministic autogenic processes of depositional systems, based on the full recognition of non-equilibrium behavior in response to steady external forcing. Recent experimental studies to explore the effects of basin water depth on the dynamics of distributary channels have brought a new geometrical scheme, here referred to as the grade index model, which is expected to make a significant step forward for development of the autostratigraphy of river deltas. Grade index (0 ≤ Gindex ≤1) is a dimensionless number that describes how close the alluvial river is to a graded state and is given as the ratio of subaerial allocation of the supplied sediment to both subaerial and subaqueous allocation of the sediment, in the form of a function of dimensionless basin water depth (h*). The grade index model for a particular geometrical setting suggests that as h* increase toward +∞, all of dimensionless magnitudes of delta progradation rate (Rpro*), alluvial aggradation rate (Ragg*), channel migration rate (Rmig*), avulsion frequency decrease toward 0, and all of dimensionless timescales of channel shifting (τs*), recurrence of channels (τr*), channel avulsion (τA*) increase toward +∞, and also that Rpro* = Ragg* = Rmig* = fA* = (τs*)-1 = (τr*)-1 = (τA* )-1 = Gindex. This grade index model, despite its simple structure, offers deep insight into the rationale of shoreline autoretreat, a typical large-scale, deterministic autogenic process that is realized by non-equilibrium response to steady base level rise. A simple geometrical modeling leads to a finding that Ppro* = (1 - Ab*) Gindex, where Ab* is a dimensionless form of the bottom surface of the deltaic deposit (Ab) given by dividing Ab with the square of autostratigraphic length scale (Λ). As the delta grows with base level rise, Ab progressively increases and then inevitably meets an event that Ab* exceeds 1 (i.e. Ab exceeds Λ2). We also

  15. Single-step electrochemical method for producing very sharp Au scanning tunneling microscopy tips

    International Nuclear Information System (INIS)

    Gingery, David; Buehlmann, Philippe

    2007-01-01

    A single-step electrochemical method for making sharp gold scanning tunneling microscopy tips is described. 3.0M NaCl in 1% perchloric acid is compared to several previously reported etchants. The addition of perchloric acid to sodium chloride solutions drastically shortens etching times and is shown by transmission electron microscopy to produce very sharp tips with a mean radius of curvature of 15 nm

  16. Discrete curved ray-tracing method for radiative transfer in an absorbing-emitting semitransparent slab with variable spatial refractive index

    International Nuclear Information System (INIS)

    Liu, L.H.

    2004-01-01

    A discrete curved ray-tracing method is developed to analyze the radiative transfer in one-dimensional absorbing-emitting semitransparent slab with variable spatial refractive index. The curved ray trajectory is locally treated as straight line and the complicated and time-consuming computation of ray trajectory is cut down. A problem of radiative equilibrium with linear variable spatial refractive index is taken as an example to examine the accuracy of the proposed method. The temperature distributions are determined by the proposed method and compared with the data in references, which are obtained by other different methods. The results show that the discrete curved ray-tracing method has a good accuracy in solving the radiative transfer in one-dimensional semitransparent slab with variable spatial refractive index

  17. In situ synthesis carbonated hydroxyapatite layers on enamel slices with acidic amino acids by a novel two-step method

    International Nuclear Information System (INIS)

    Wu, Xiaoguang; Zhao, Xu; Li, Yi; Yang, Tao; Yan, Xiujuan; Wang, Ke

    2015-01-01

    In situ fabrication of carbonated hydroxyapatite (CHA) remineralization layer on an enamel slice was completed in a novel, biomimetic two-step method. First, a CaCO 3 layer was synthesized on the surface of demineralized enamel using an acidic amino acid (aspartic acid or glutamate acid) as a soft template. Second, at the same concentration of the acidic amino acid, rod-like carbonated hydroxyapatite was produced with the CaCO 3 layer as a sacrificial template and a reactant. The morphology, crystallinity and other physicochemical properties of the crystals were characterized using field emission scanning electron microscopy (FESEM), Fourier transform infrared spectrometry (FTIR), X-ray diffraction (XRD) and energy-dispersive X-ray analysis (EDAX), respectively. Acidic amino acid could promote the uniform deposition of hydroxyapatite with rod-like crystals via absorption of phosphate and carbonate ions from the reaction solution. Moreover, compared with hydroxyapatite crystals coated on the enamel when synthesized by a one-step method, the CaCO 3 coating that was synthesized in the first step acted as an active bridge layer and sacrificial template. It played a vital role in orienting the artificial coating layer through the template effect. The results show that the rod-like carbonated hydroxyapatite crystals grow into bundles, which are similar in size and appearance to prisms in human enamel, when using the two-step method with either aspartic acid or acidic glutamate (20.00 mmol/L). - Graphical abstract: FESEM images of enamel slices etched for 60 s and repaired by the two-step method with Glu concentration of 20.00 mmol/L. (A) The boundary (dotted line) of the repaired areas (b) and unrepaired areas (a). (Some selected areas of etched enamel slices were coated with a nail polish before the reaction, which was removed by acetone after the reaction); (B) high magnification image of Ga, (C) high magnification image of Gb. In situ fabrication of carbonated

  18. In situ synthesis carbonated hydroxyapatite layers on enamel slices with acidic amino acids by a novel two-step method

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Xiaoguang [Department of Pediatric Dentistry, The Hospital of Stomatology, Jilin University, Changchun 130021 (China); Zhao, Xu [College of Chemistry, Jilin University, Changchun 130021 (China); Li, Yi, E-mail: lyi99@jlu.edu.cn [Department of Pediatric Dentistry, The Hospital of Stomatology, Jilin University, Changchun 130021 (China); Yang, Tao [Department of Stomatology, Children' s Hospital of Changchun, 130051 (China); Yan, Xiujuan; Wang, Ke [Department of Pediatric Dentistry, The Hospital of Stomatology, Jilin University, Changchun 130021 (China)

    2015-09-01

    In situ fabrication of carbonated hydroxyapatite (CHA) remineralization layer on an enamel slice was completed in a novel, biomimetic two-step method. First, a CaCO{sub 3} layer was synthesized on the surface of demineralized enamel using an acidic amino acid (aspartic acid or glutamate acid) as a soft template. Second, at the same concentration of the acidic amino acid, rod-like carbonated hydroxyapatite was produced with the CaCO{sub 3} layer as a sacrificial template and a reactant. The morphology, crystallinity and other physicochemical properties of the crystals were characterized using field emission scanning electron microscopy (FESEM), Fourier transform infrared spectrometry (FTIR), X-ray diffraction (XRD) and energy-dispersive X-ray analysis (EDAX), respectively. Acidic amino acid could promote the uniform deposition of hydroxyapatite with rod-like crystals via absorption of phosphate and carbonate ions from the reaction solution. Moreover, compared with hydroxyapatite crystals coated on the enamel when synthesized by a one-step method, the CaCO{sub 3} coating that was synthesized in the first step acted as an active bridge layer and sacrificial template. It played a vital role in orienting the artificial coating layer through the template effect. The results show that the rod-like carbonated hydroxyapatite crystals grow into bundles, which are similar in size and appearance to prisms in human enamel, when using the two-step method with either aspartic acid or acidic glutamate (20.00 mmol/L). - Graphical abstract: FESEM images of enamel slices etched for 60 s and repaired by the two-step method with Glu concentration of 20.00 mmol/L. (A) The boundary (dotted line) of the repaired areas (b) and unrepaired areas (a). (Some selected areas of etched enamel slices were coated with a nail polish before the reaction, which was removed by acetone after the reaction); (B) high magnification image of Ga, (C) high magnification image of Gb. In situ fabrication of

  19. A Diagnosis Method for Rotation Machinery Faults Based on Dimensionless Indexes Combined with K-Nearest Neighbor Algorithm

    Directory of Open Access Journals (Sweden)

    Jianbin Xiong

    2015-01-01

    Full Text Available It is difficult to well distinguish the dimensionless indexes between normal petrochemical rotating machinery equipment and those with complex faults. When the conflict of evidence is too big, it will result in uncertainty of diagnosis. This paper presents a diagnosis method for rotation machinery fault based on dimensionless indexes combined with K-nearest neighbor (KNN algorithm. This method uses a KNN algorithm and an evidence fusion theoretical formula to process fuzzy data, incomplete data, and accurate data. This method can transfer the signals from the petrochemical rotating machinery sensors to the reliability manners using dimensionless indexes and KNN algorithm. The input information is further integrated by an evidence synthesis formula to get the final data. The type of fault will be decided based on these data. The experimental results show that the proposed method can integrate data to provide a more reliable and reasonable result, thereby reducing the decision risk.

  20. Ranking Fuzzy Numbers with a Distance Method using Circumcenter of Centroids and an Index of Modality

    Directory of Open Access Journals (Sweden)

    P. Phani Bushan Rao

    2011-01-01

    Full Text Available Ranking fuzzy numbers are an important aspect of decision making in a fuzzy environment. Since their inception in 1965, many authors have proposed different methods for ranking fuzzy numbers. However, there is no method which gives a satisfactory result to all situations. Most of the methods proposed so far are nondiscriminating and counterintuitive. This paper proposes a new method for ranking fuzzy numbers based on the Circumcenter of Centroids and uses an index of optimism to reflect the decision maker's optimistic attitude and also an index of modality that represents the neutrality of the decision maker. This method ranks various types of fuzzy numbers which include normal, generalized trapezoidal, and triangular fuzzy numbers along with crisp numbers with the particularity that crisp numbers are to be considered particular cases of fuzzy numbers.

  1. Two-step extraction method for lead isotope fractionation to reveal anthropogenic lead pollution.

    Science.gov (United States)

    Katahira, Kenshi; Moriwaki, Hiroshi; Kamura, Kazuo; Yamazaki, Hideo

    2018-05-28

    This study developed the 2-step extraction method which eluted the Pb adsorbing on the surface of sediments in the first solution by aqua regia and extracted the Pb absorbed inside particles into the second solution by mixed acid of nitric acid, hydrofluoric acid and hydrogen peroxide solution. We applied the method to sediments in the enclosed water area and found out that the isotope ratios of Pb in the second solution represented those of natural origin. This advantage of the method makes it possible to distinguish the Pb between natural origin and anthropogenic source on the basis of the isotope ratios. The results showed that the method was useful to discuss the Pb sources and that anthropogenic Pb in the sediment samples analysed was mainly derived from China because of transboundary air pollution.

  2. [Exploration of one-step preparation of Ganoderma lucidum multicomponent microemulsion].

    Science.gov (United States)

    He, Jun-Jie; Chen, Yan; Du, Meng; Cao, Wei; Yuan, Ling; Zheng, Li-Yan

    2013-03-01

    To explore one-step method for the preparation of Ganoderma lucidum multicomponent microemulsion, according to the dissolution characteristics of triterpenes and polysaccharides in Ganoderma lucidum, formulation of the microemulsion was optimized. The optimal blank microemulsion was used as a solvent to sonicate the Ganoderma lucidum powder to prepare the multicomponent microemulsion, besides, its physicochemical properties were compared with the microemulsion made by conventional method. The results showed that the multicomponent microemulsion was characterized as (43.32 +/- 6.82) nm in size, 0.173 +/- 0.025 in polydispersity index (PDI) and -(3.98 +/- 0.82) mV in zeta potential. The contents of Ganoderma lucidum triterpenes and polysaccharides were (5.95 +/- 0.32) and (7.58 +/- 0.44) mg x mL(-1), respectively. Sonicating Ganoderma lucidum powder by blank microemulsion could prepare the multicomponent microemulsion. Compared with the conventional method, this method is simple and low cost, which is suitable for industrial production.

  3. A two-stage method for inverse medium scattering

    KAUST Repository

    Ito, Kazufumi

    2013-03-01

    We present a novel numerical method to the time-harmonic inverse medium scattering problem of recovering the refractive index from noisy near-field scattered data. The approach consists of two stages, one pruning step of detecting the scatterer support, and one resolution enhancing step with nonsmooth mixed regularization. The first step is strictly direct and of sampling type, and it faithfully detects the scatterer support. The second step is an innovative application of nonsmooth mixed regularization, and it accurately resolves the scatterer size as well as intensities. The nonsmooth model can be efficiently solved by a semi-smooth Newton-type method. Numerical results for two- and three-dimensional examples indicate that the new approach is accurate, computationally efficient, and robust with respect to data noise. © 2012 Elsevier Inc.

  4. Two-Step Injection Method for Collecting Digital Evidence in Digital Forensics

    Directory of Open Access Journals (Sweden)

    Nana Rachmana Syambas

    2015-01-01

    Full Text Available In digital forensic investigations, the investigators take digital evidence from computers, laptops or other electronic goods. There are many complications when a suspect or related person does not want to cooperate or has removed digital evidence. A lot of research has been done with the goal of retrieving data from flash memory or other digital storage media from which the content has been deleted. Unfortunately, such methods cannot guarantee that all data will be recovered. Most data can only be recovered partially and sometimes not perfectly, so that some or all files cannot be opened. This paper proposes the development of a new method for the retrieval of digital evidence called the Two-Step Injection method (TSI. It focuses on the prevention of the loss of digital evidence through the deletion of data by suspects or other parties. The advantage of this method is that the system works in secret and can be combined with other digital evidence applications that already exist, so that the accuracy and completeness of the resulting digital evidence can be improved. An experiment to test the effectiveness of the method was set up. The developed TSI system worked properly and had a 100% success rate.

  5. Adaptive step-size algorithm for Fourier beam-propagation method with absorbing boundary layer of auto-determined width.

    Science.gov (United States)

    Learn, R; Feigenbaum, E

    2016-06-01

    Two algorithms that enhance the utility of the absorbing boundary layer are presented, mainly in the framework of the Fourier beam-propagation method. One is an automated boundary layer width selector that chooses a near-optimal boundary size based on the initial beam shape. The second algorithm adjusts the propagation step sizes based on the beam shape at the beginning of each step in order to reduce aliasing artifacts.

  6. The method of quick satellite aiming with 3-Steps on the mobile satellite station

    Directory of Open Access Journals (Sweden)

    Sheng Liang

    2017-02-01

    Full Text Available The study analyses and concludes the technology of the satellite aiming during real-time broadcast of mobile video.We conclude a method of quick satellite aiming with 3-steps according to practical exercises and users' requirement to meet situation of facts and standardized operation,which can improve efficiency and quality of service.

  7. Indexing data cubes for content-based searches in radio astronomy

    Science.gov (United States)

    Araya, M.; Candia, G.; Gregorio, R.; Mendoza, M.; Solar, M.

    2016-01-01

    Methods for observing space have changed profoundly in the past few decades. The methods needed to detect and record astronomical objects have shifted from conventional observations in the optical range to more sophisticated methods which permit the detection of not only the shape of an object but also the velocity and frequency of emissions in the millimeter-scale wavelength range and the chemical substances from which they originate. The consolidation of radio astronomy through a range of global-scale projects such as the Very Long Baseline Array (VLBA) and the Atacama Large Millimeter/submillimeter Array (ALMA) reinforces the need to develop better methods of data processing that can automatically detect regions of interest (ROIs) within data cubes (position-position-velocity), index them and facilitate subsequent searches via methods based on queries using spatial coordinates and/or velocity ranges. In this article, we present the development of an automatic system for indexing ROIs in data cubes that is capable of automatically detecting and recording ROIs while reducing the necessary storage space. The system is able to process data cubes containing megabytes of data in fractions of a second without human supervision, thus allowing it to be incorporated into a production line for displaying objects in a virtual observatory. We conducted a set of comprehensive experiments to illustrate how our system works. As a result, an index of 3% of the input size was stored in a spatial database, representing a compression ratio equal to 33:1 over an input of 20.875 GB, achieving an index of 773 MB approximately. On the other hand, a single query can be evaluated over our system in a fraction of second, showing that the indexing step works as a shock-absorber of the computational time involved in data cube processing. The system forms part of the Chilean Virtual Observatory (ChiVO), an initiative which belongs to the International Virtual Observatory Alliance (IVOA) that

  8. Occlusion culling and calculation for a computer generated hologram using spatial frequency index method

    International Nuclear Information System (INIS)

    Zhao, Kai; Yan, Xingpeng; Jiang, Xiaoyu; Huang, Yingqing

    2015-01-01

    A spatial frequency index method is proposed to cull occlusion and generate a hologram. Object points with the same spatial frequency are put into a set for their mutual occlusion. The hidden surfaces of the three-dimensional (3D) scene are quickly removed through culling the object points that are furthest from the hologram plane in the set. The phases of plane wave, which are only interrelated with the spatial frequencies, are precomputed and stored in a table. According to the spatial frequency of the object points, the phases of plane wave for generating fringes are obtained directly from the table. Three 3D scenes are chosen to verify the spatial frequency index method. Both numerical simulation and optical reconstruction are performed. Experimental results demonstrate that the proposed method can cull the hidden surfaces of the 3D scene correctly. The occlusion effect of the 3D scene can be well reproduced. The computational speed is better than that obtained using conventional methods but is still time-consuming. (paper)

  9. Preferences for partner notification method: variation in responses between respondents as index patients and contacts.

    Science.gov (United States)

    Apoola, A; Radcliffe, K W; Das, S; Robshaw, V; Gilleran, G; Kumari, B S; Boothby, M; Rajakumar, R

    2007-07-01

    There have been very few studies focusing on what form of communication patients would find acceptable from a clinic. This study looks at the differences in preferences for various partner notification methods when the respondents were index patients compared with when they had to be contacted because a partner had a sexually transmitted infection (STI). There were 2544 respondents. When the clinic had to notify partners, respondents were more likely to report the method as good when a partner had an STI and they were being contacted compared with when the respondents had an infection and the partner was being contacted. The opposite was true for patient referral partner notification. Therefore, there are variations in the preferences of respondents for partner notification method, which depend on whether they see themselves as index patients or contacts.

  10. Computed tomography of x-ray index of refraction using the diffraction enhanced imaging method

    International Nuclear Information System (INIS)

    Dilmanian, F.A.; Ren, B.; Wu, X.Y.; Orion, I.; Zhong, Z.; Thomlinson, W.C.; Chapman, L.D.

    2000-01-01

    Diffraction enhanced imaging (DEI) is a new, synchrotron-based, x-ray radiography method that uses monochromatic, fan-shaped beams, with an analyser crystal positioned between the subject and the detector. The analyser allows the detection of only those x-rays transmitted by the subject that fall into the acceptance angle (central part of the rocking curve) of the monochromator/analyser system. As shown by Chapman et al , in addition to the x-ray attenuation, the method provides information on the out-of-plane angular deviation of x-rays. New images result in which the image contrast depends on the x-ray index of refraction and on the yield of small-angle scattering, respectively. We implemented DEI in the tomography mode at the National Synchrotron Light Source using 22 keV x-rays, and imaged a cylindrical acrylic phantom that included oil-filled, slanted channels. The resulting 'refraction CT image' shows the pure image of the out-of-plane gradient of the x-ray index of refraction. No image artefacts were present, indicating that the CT projection data were a consistent set. The 'refraction CT image' signal is linear with the gradient of the refractive index, and its value is equal to that expected. The method, at the energy used or higher, has the potential for use in clinical radiography and in industry. (author)

  11. Characteristic analysis of laser isotope separation process by two-step photodissociation method

    International Nuclear Information System (INIS)

    Okamoto, Tsuyoshi; Suzuki, Atsuyuki; Kiyose, Ryohei

    1981-01-01

    A large number of laser isotope separation experiments have been performed actively in many countries. In this paper, the selective two-step photodissociation method is chosen and simultaneous nonlinear differential equations that express the separation process are solved directly by using computer. Predicted separation factors are investigated in relation to the incident pulse energy and the concentration of desired molecules. Furthermore, the concept of separative work is used to evaluate the results of separation for this method. It is shown from an example of numerical calculation that a very large separation factor can be obtained if the concentration of desired molecules is lowered and two laser pulses to be closely synchronized are not always required in operation for the photodissociation of molecules. (author)

  12. Validity of the Stages of Change in Steps instrument (SoC-Step) for achieving the physical activity goal of 10,000 steps per day.

    Science.gov (United States)

    Rosenkranz, Richard R; Duncan, Mitch J; Caperchione, Cristina M; Kolt, Gregory S; Vandelanotte, Corneel; Maeder, Anthony J; Savage, Trevor N; Mummery, W Kerry

    2015-11-30

    Physical activity (PA) offers numerous benefits to health and well-being, but most adults are not sufficiently physically active to afford such benefits. The 10,000 steps campaign has been a popular and effective approach to promote PA. The Transtheoretical Model posits that individuals have varying levels of readiness for health behavior change, known as Stages of Change (Precontemplation, Contemplation, Preparation, Action, and Maintenance). Few validated assessment instruments are available for determining Stages of Change in relation to the PA goal of 10,000 steps per day. The purpose of this study was to assess the criterion-related validity of the SoC-Step, a brief 10,000 steps per day Stages of Change instrument. Participants were 504 Australian adults (176 males, 328 females, mean age = 50.8 ± 13.0 years) from the baseline sample of the Walk 2.0 randomized controlled trial. Measures included 7-day accelerometry (Actigraph GT3X), height, weight, and self-reported intention, self-efficacy, and SoC-Step: Stages of Change relative to achieving 10,000 steps per day. Kruskal-Wallis H tests with pairwise comparisons were used to determine whether participants differed by stage, according to steps per day, general health, body mass index, intention, and self-efficacy to achieve 10,000 steps per day. Binary logistic regression was used to test the hypothesis that participants in Maintenance or Action stages would have greater likelihood of meeting the 10,000 steps goal, in comparison to participants in the other three stages. Consistent with study hypotheses, participants in Precontemplation had significantly lower intention scores than those in Contemplation (p = 0.003) or Preparation (p per day (OR = 3.11; 95 % CI = 1.66,5.83) compared to those in Precontemplation, Contemplation, or Preparation. Intention (p per day. Australian New Zealand Clinical Trials Registry reference: ACTRN12611000157976 World Health Organization Universal Trial

  13. Method to create gradient index in a polymer

    Science.gov (United States)

    Dirk, Shawn M; Johnson, Ross Stefan; Boye, Robert; Descour, Michael R; Sweatt, William C; Wheeler, David R; Kaehr, Bryan James

    2014-10-14

    Novel photo-writable and thermally switchable polymeric materials exhibit a refractive index change of .DELTA.n.gtoreq.1.0 when exposed to UV light or heat. For example, lithography can be used to convert a non-conjugated precursor polymer to a conjugated polymer having a higher index-of-refraction. Further, two-photon lithography can be used to pattern high-spatial frequency structures.

  14. The partial duration series method in regional index-flood modeling

    DEFF Research Database (Denmark)

    Madsen, Henrik; Rosbjerg, Dan

    1997-01-01

    A regional index-flood method based on the partial duration series model is introduced. The model comprises the assumptions of a Poisson-distributed number of threshold exceedances and generalized Pareto (GP) distributed peak magnitudes. The regional T-year event estimator is based on a regional...... estimator is superior to the at-site estimator even in extremely heterogenous regions, the performance of the regional estimator being relatively better in regions with a negative shape parameter. When the record length increases, the relative performance of the regional estimator decreases, but it is still...

  15. Ray transference of a system with radial gradi- ent index

    Directory of Open Access Journals (Sweden)

    W. F. Harris

    2012-12-01

    Full Text Available The ray transference is central to the understanding of the first-order optical character of an optical system including the visual optical system of the eye.  It can be calculated for dioptric and catadioptric systems from a knowledge of curvatures, tilts and spacing of surfaces in the system provided the material between successive surfaces has a uniform index of refraction.  However the index of the natural lens of the eye is not uniform but varies with position.  There is a need, therefore, for a method of calculating the transference of systems containing such gradient-index elements.  As a first step this paper shows that the transference of elements in which the index varies radially can be obtained directly from published formulae.  The transferences of radial-gradient systems are examined.  Expressions are derived for several properties including the power, the front- and back-surface powers and the locations of the cardinal points.  Equations are obtained for rays through such systems and for the locations of images of object points through them.  Numerical examples are presented in the appen-dix. (S Afr Optom 2012 71(2 57-63

  16. A new multi-step technique with differential transform method for analytical solution of some nonlinear variable delay differential equations.

    Science.gov (United States)

    Benhammouda, Brahim; Vazquez-Leal, Hector

    2016-01-01

    This work presents an analytical solution of some nonlinear delay differential equations (DDEs) with variable delays. Such DDEs are difficult to treat numerically and cannot be solved by existing general purpose codes. A new method of steps combined with the differential transform method (DTM) is proposed as a powerful tool to solve these DDEs. This method reduces the DDEs to ordinary differential equations that are then solved by the DTM. Furthermore, we show that the solutions can be improved by Laplace-Padé resummation method. Two examples are presented to show the efficiency of the proposed technique. The main advantage of this technique is that it possesses a simple procedure based on a few straight forward steps and can be combined with any analytical method, other than the DTM, like the homotopy perturbation method.

  17. The time to trade-off method versus the EQ-5D index to determine health utility in patients with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Dmitriy Vladimirovich Goryachev

    2010-01-01

    The values of the utility index calculated by TTO failed to correlate with those of HAQ and EQ-5D. The disease duration was unrelated to the values of the utility index calculated by any of the methods used. The association of TTO index was found only for VAS-GH "thermometer". Conclusion. EQ-5D index and VAS-GH are the methods of choice in determining health utility for a clinicoeconomic analysis in patients with RA.

  18. Creating a spatially-explicit index: a method for assessing the global wildfire-water risk

    Science.gov (United States)

    Robinne, François-Nicolas; Parisien, Marc-André; Flannigan, Mike; Miller, Carol; Bladon, Kevin D.

    2017-04-01

    The wildfire-water risk (WWR) has been defined as the potential for wildfires to adversely affect water resources that are important for downstream ecosystems and human water needs for adequate water quantity and quality, therefore compromising the security of their water supply. While tools and methods are numerous for watershed-scale risk analysis, the development of a toolbox for the large-scale evaluation of the wildfire risk to water security has only started recently. In order to provide managers and policy-makers with an adequate tool, we implemented a method for the spatial analysis of the global WWR based on the Driving forces-Pressures-States-Impacts-Responses (DPSIR) framework. This framework relies on the cause-and-effect relationships existing between the five categories of the DPSIR chain. As this approach heavily relies on data, we gathered an extensive set of spatial indicators relevant to fire-induced hydrological hazards and water consumption patterns by human and natural communities. When appropriate, we applied a hydrological routing function to our indicators in order to simulate downstream accumulation of potentially harmful material. Each indicator was then assigned a DPSIR category. We collapsed the information in each category using a principal component analysis in order to extract the most relevant pixel-based information provided by each spatial indicator. Finally, we compiled our five categories using an additive indexation process to produce a spatially-explicit index of the WWR. A thorough sensitivity analysis has been performed in order to understand the relationship between the final risk values and the spatial pattern of each category used during the indexation. For comparison purposes, we aggregated index scores by global hydrological regions, or hydrobelts, to get a sense of regional DPSIR specificities. This rather simple method does not necessitate the use of complex physical models and provides a scalable and efficient tool

  19. A novel two-step method for screening shade tolerant mutant plants via dwarfism

    Directory of Open Access Journals (Sweden)

    Wei Li

    2016-10-01

    Full Text Available When subjected to shade, plants undergo rapid shoot elongation, which often makes them more prone to disease and mechanical damage. Shade-tolerant plants can be difficult to breed; however, they offer a substantial benefit over other varieties in low-light areas. Although perennial ryegrass (Lolium perenne L. is a popular species of turf grasses because of their good appearance and fast establishment, the plant normally does not perform well under shade conditions. It has been reported that, in turfgrass, induced dwarfism can enhance shade tolerance. Here we describe a two-step procedure for isolating shade tolerant mutants of perennial ryegrass by first screening for dominant dwarf mutants, and then screening dwarf plants for shade tolerance. The two-step screening process to isolate shade tolerant mutants can be done efficiently with limited space at early seedling stages, which enables quick and efficient isolation of shade tolerant mutants, and thus facilitates development of shade tolerant new cultivars of turfgrasses. Using the method, we isolated 136 dwarf mutants from 300,000 mutagenized seeds, with 65 being shade tolerant (0.022%. When screened directly for shade tolerance, we recovered only four mutants from a population of 150,000 (0.003% mutagenized seeds. One shade tolerant mutant, shadow-1, was characterized in detail. In addition to dwarfism, shadow-1 and its sexual progeny displayed high degrees of tolerance to both natural and artificial shade. We showed that endogenous gibberellin (GA content in shadow-1 was higher than wild-type controls, and shadow-1 was also partially GA insensitive. Our novel, simple and effective two-step screening method should be applicable to breeding shade tolerant cultivars of turfgrasses, ground covers, and other economically important crop plants that can be used under canopies of existing vegetation to increase productivity per unit area of land.

  20. Current lipid extraction methods are significantly enhanced adding a water treatment step in Chlorella protothecoides.

    Science.gov (United States)

    Ren, Xiaojie; Zhao, Xinhe; Turcotte, François; Deschênes, Jean-Sébastien; Tremblay, Réjean; Jolicoeur, Mario

    2017-02-11

    Microalgae have the potential to rapidly accumulate lipids of high interest for the food, cosmetics, pharmaceutical and energy (e.g. biodiesel) industries. However, current lipid extraction methods show efficiency limitation and until now, extraction protocols have not been fully optimized for specific lipid compounds. The present study thus presents a novel lipid extraction method, consisting in the addition of a water treatment of biomass between the two-stage solvent extraction steps of current extraction methods. The resulting modified method not only enhances lipid extraction efficiency, but also yields a higher triacylglycerols (TAG) ratio, which is highly desirable for biodiesel production. Modification of four existing methods using acetone, chloroform/methanol (Chl/Met), chloroform/methanol/H 2 O (Chl/Met/H 2 O) and dichloromethane/methanol (Dic/Met) showed respective lipid extraction yield enhancement of 72.3, 35.8, 60.3 and 60.9%. The modified acetone method resulted in the highest extraction yield, with 68.9 ± 0.2% DW total lipids. Extraction of TAG was particularly improved with the water treatment, especially for the Chl/Met/H 2 O and Dic/Met methods. The acetone method with the water treatment led to the highest extraction level of TAG with 73.7 ± 7.3 µg/mg DW, which is 130.8 ± 10.6% higher than the maximum value obtained for the four classical methods (31.9 ± 4.6 µg/mg DW). Interestingly, the water treatment preferentially improved the extraction of intracellular fractions, i.e. TAG, sterols, and free fatty acids, compared to the lipid fractions of the cell membranes, which are constituted of phospholipids (PL), acetone mobile polar lipids and hydrocarbons. Finally, from the 32 fatty acids analyzed for both neutral lipids (NL) and polar lipids (PL) fractions, it is clear that the water treatment greatly improves NL-to-PL ratio for the four standard methods assessed. Water treatment of biomass after the first solvent extraction step

  1. Influence of application methods of one-step self-etching adhesives on microtensile bond strength

    Directory of Open Access Journals (Sweden)

    Chul-Kyu Choi,

    2011-05-01

    Full Text Available Objectives The purpose of this study was to evaluate the effect of various application methods of one-step self-etch adhesives to microtensile resin-dentin bond strength. Materials and Methods Thirty-six extracted human molars were used. The teeth were assigned randomly to twelve groups (n = 15, according to the three different adhesive systems (Clearfil Tri-S Bond, Adper Prompt L-Pop, G-Bond and application methods. The adhesive systems were applied on the dentin as follows: 1 The single coating, 2 The double coating, 3 Manual agitation, 4 Ultrasonic agitation. Following the adhesive application, light-cure composite resin was constructed. The restored teeth were stored in distilled water at room temperature for 24 hours, and prepared 15 specimens per groups. Then microtensile bond strength was measured and the failure mode was examined. Results Manual agitation and ultrasonic agitation of adhesive significantly increased the microtensile bond strength than single coating and double coating did. Double coating of adhesive significantly increased the microtensile bond strength than single coating did and there was no significant difference between the manual agitation and ultrasonic agitation group. There was significant difference in microtensile bonding strength among all adhesives and Clearfil Tri-S Bond showed the highest bond strength. Conclusions In one-step self-etching adhesives, there was significant difference according to application methods and type of adhesives. No matter of the material, the manual or ultrasonic agitation of the adhesive showed significantly higher microtensile bond strength.

  2. Proper Methodology and Methods of Collecting and Analyzing Slavery Data: An Examination of the Global Slavery Index

    Directory of Open Access Journals (Sweden)

    Andrew Guth

    2014-11-01

    Full Text Available The Global Slavery Index aims to, among other objectives, recognize the forms, size, and scope of slavery worldwide as well as the strengths and weaknesses of individual countries. An analysis of the Index’s methods exposes significant and critical weaknesses and raises questions into its replicability and validity. The Index may prove more valuable in the future if proper methods are implemented, but the longer improper methods are used the more damage is done to the public policy debate on slavery by advancing data and policy that is not based on sound methodology. To implement proper methods, a committee of sophisticated methodologists needs to develop measurement tools and constantly analyze and refine these methods over the years as data is collected.

  3. Acceleration of step and linear discontinuous schemes for the method of characteristics in DRAGON5

    Directory of Open Access Journals (Sweden)

    Alain Hébert

    2017-09-01

    Full Text Available The applicability of the algebraic collapsing acceleration (ACA technique to the method of characteristics (MOC in cases with scattering anisotropy and/or linear sources was investigated. Previously, the ACA was proven successful in cases with isotropic scattering and uniform (step sources. A presentation is first made of the MOC implementation, available in the DRAGON5 code. Two categories of schemes are available for integrating the propagation equations: (1 the first category is based on exact integration and leads to the classical step characteristics (SC and linear discontinuous characteristics (LDC schemes and (2 the second category leads to diamond differencing schemes of various orders in space. The acceleration of these MOC schemes using a combination of the generalized minimal residual [GMRES(m] method preconditioned with the ACA technique was focused on. Numerical results are provided for a two-dimensional (2D eight-symmetry pressurized water reactor (PWR assembly mockup in the context of the DRAGON5 code.

  4. A multi-step dealloying method to produce nanoporous gold with no volume change and minimal cracking

    Energy Technology Data Exchange (ETDEWEB)

    Sun Ye [Department of Chemical and Materials Engineering, University of Kentucky, 177 F. Paul Anderson Tower, Lexington, KY 40506 (United States); Balk, T. John [Department of Chemical and Materials Engineering, University of Kentucky, 177 F. Paul Anderson Tower, Lexington, KY 40506 (United States)], E-mail: balk@engr.uky.edu

    2008-05-15

    We report a simple two-step dealloying method for producing bulk nanoporous gold with no volume change and no significant cracking. The galvanostatic dealloying method used here appears superior to potentiostatic methods for fabricating millimeter-scale samples. Care must be taken when imaging the nanoscale, interconnected sponge-like structure with a focused ion beam, as even brief exposure caused immediate and extensive cracking of nanoporous gold, as well as ligament coarsening at the surface00.

  5. Symplectic integrators with adaptive time steps

    Science.gov (United States)

    Richardson, A. S.; Finn, J. M.

    2012-01-01

    In recent decades, there have been many attempts to construct symplectic integrators with variable time steps, with rather disappointing results. In this paper, we identify the causes for this lack of performance, and find that they fall into two categories. In the first, the time step is considered a function of time alone, Δ = Δ(t). In this case, backward error analysis shows that while the algorithms remain symplectic, parametric instabilities may arise because of resonance between oscillations of Δ(t) and the orbital motion. In the second category the time step is a function of phase space variables Δ = Δ(q, p). In this case, the system of equations to be solved is analyzed by introducing a new time variable τ with dt = Δ(q, p) dτ. The transformed equations are no longer in Hamiltonian form, and thus do not benefit from integration methods which would be symplectic for Hamiltonian systems. We analyze two methods for integrating the transformed equations which do, however, preserve the structure of the original equations. The first is an extended phase space method, which has been successfully used in previous studies of adaptive time step symplectic integrators. The second, novel, method is based on a non-canonical mixed-variable generating function. Numerical trials for both of these methods show good results, without parametric instabilities or spurious growth or damping. It is then shown how to adapt the time step to an error estimate found by backward error analysis, in order to optimize the time-stepping scheme. Numerical results are obtained using this formulation and compared with other time-stepping schemes for the extended phase space symplectic method.

  6. Study of Vee Plate Manufacturing Method for Indexing Table

    OpenAIRE

    Yeon Taek OH

    2015-01-01

    The indexing tables have recently become an increasing necessity for improving the precision and accuracy of angle measurement. The indexing table employs a vee and 3 balls kinematic location system. A 6 point contact kinematic design concept of ball and vee groove was used, because the ball and vee groove system can attain good repeatability and has good rigidity. The vee plays an important role as the indexing angle and locking mechanism. Also eccentricity is an important factor as alignmen...

  7. Using a Two-Step Method to Measure Transgender Identity in Latin America/the Caribbean, Portugal, and Spain

    Science.gov (United States)

    Reisner, Sari L.; Biello, Katie; Rosenberger, Joshua G.; Austin, S. Bryn; Haneuse, Sebastien; Perez-Brumer, Amaya; Novak, David S.; Mimiaga, Matthew J.

    2014-01-01

    Few comparative data are available internationally to examine health differences by transgender identity. A barrier to monitoring the health and well-being of transgender people is the lack of inclusion of measures to assess natal sex/gender identity status in surveys. Data were from a cross-sectional anonymous online survey of members (n > 36,000) of a sexual networking website targeting men who have sex with men in Spanish- and Portuguese-speaking countries/ territories in Latin America/the Caribbean, Portugal, and Spain. Natal sex/gender identity status was assessed using a two-step method (Step 1: assigned birth sex, Step 2: current gender identity). Male-to-female (MTF) and female-to-male (FTM) participants were compared to non-transgender males in age-adjusted regression models on socioeconomic status (SES) (education, income, sex work), masculine gender conformity, psychological health and well-being (lifetime suicidality, past-week depressive distress, positive self-worth, general self-rated health, gender related stressors), and sexual health (HIV-infection, past-year STIs, past-3 month unprotected anal or vaginal sex). The two-step method identified 190 transgender participants (0.54%; 158 MTF, 32 FTM). Of the 12 health-related variables, six showed significant differences between the three groups: SES, masculine gender conformity, lifetime suicidality, depressive distress, positive self-worth, and past-year genital herpes. A two-step approach is recommended for health surveillance efforts to assess natal sex/gender identity status. Cognitive testing to formally validate assigned birth sex and current gender identity survey items in Spanish and Portuguese is encouraged. PMID:25030120

  8. A multi-time-step noise reduction method for measuring velocity statistics from particle tracking velocimetry

    Science.gov (United States)

    Machicoane, Nathanaël; López-Caballero, Miguel; Bourgoin, Mickael; Aliseda, Alberto; Volk, Romain

    2017-10-01

    We present a method to improve the accuracy of velocity measurements for fluid flow or particles immersed in it, based on a multi-time-step approach that allows for cancellation of noise in the velocity measurements. Improved velocity statistics, a critical element in turbulent flow measurements, can be computed from the combination of the velocity moments computed using standard particle tracking velocimetry (PTV) or particle image velocimetry (PIV) techniques for data sets that have been collected over different values of time intervals between images. This method produces Eulerian velocity fields and Lagrangian velocity statistics with much lower noise levels compared to standard PIV or PTV measurements, without the need of filtering and/or windowing. Particle displacement between two frames is computed for multiple different time-step values between frames in a canonical experiment of homogeneous isotropic turbulence. The second order velocity structure function of the flow is computed with the new method and compared to results from traditional measurement techniques in the literature. Increased accuracy is also demonstrated by comparing the dissipation rate of turbulent kinetic energy measured from this function against previously validated measurements.

  9. Step-to-step reproducibility and asymmetry to study gait auto-optimization in healthy and cerebral palsied subjects.

    Science.gov (United States)

    Descatoire, A; Femery, V; Potdevin, F; Moretto, P

    2009-05-01

    The purpose of our study was to compare plantar pressure asymmetry and step-to-step reproducibility in both able-bodied persons and two groups of hemiplegics. The relevance of the research was to determine the efficiency of asymmetry and reproducibility as indexes for diagnosis and rehabilitation processes. This study comprised 31 healthy young subjects and 20 young subjects suffering from cerebral palsy hemiplegia assigned to two groups of 10 subjects according to the severity of their musculoskeletal disorders. The peaks of plantar pressure and the time to peak pressure were recorded with an in-shoe measurement system. The intra-individual coefficient of variability was calculated to indicate the consistency of plantar pressure during walking and to define gait stability. The effect size was computed to quantify the asymmetry and measurements were conducted at eight footprint locations. Results indicated few differences in step-to-step reproducibility between the healthy group and the less spastic group while the most affected group showed a more asymmetrical and unstable gait. From the concept of self-optimisation and depending on the neuromotor disorders the organism could make priorities based on pain, mobility, stability or energy expenditure to develop the best gait auto-optimisation.

  10. Novel optical solitary waves and modulation instability analysis for the coupled nonlinear Schrödinger equation in monomode step-index optical fibers

    Science.gov (United States)

    Inc, Mustafa; Aliyu, Aliyu Isa; Yusuf, Abdullahi; Baleanu, Dumitru

    2018-01-01

    This paper addresses the coupled nonlinear Schrödinger equation (CNLSE) in monomode step-index in optical fibers which describes the nonlinear modulations of two monochromatic waves, whose group velocities are almost equal. A class of dark, bright, dark-bright and dark-singular optical solitary wave solutions of the model are constructed using the complex envelope function ansatz. Singular solitary waves are also retrieved as bye products of the in integration scheme. This naturally lead to some constraint conditions placed on the solitary wave parameters which must hold for the solitary waves to exist. The modulation instability (MI) analysis of the model is studied based on the standard linear-stability analysis. Numerical simulation and physical interpretations of the obtained results are demonstrated. It is hoped that the results reported in this paper can enrich the nonlinear dynamical behaviors of the CNLSE.

  11. The Finite-Surface Method for incompressible flow: a step beyond staggered grid

    Science.gov (United States)

    Hokpunna, Arpiruk; Misaka, Takashi; Obayashi, Shigeru

    2017-11-01

    We present a newly developed higher-order finite surface method for the incompressible Navier-Stokes equations (NSE). This method defines the velocities as a surface-averaged value on the surfaces of the pressure cells. Consequently, the mass conservation on the pressure cells becomes an exact equation. The only things left to approximate is the momentum equation and the pressure at the new time step. At certain conditions, the exact mass conservation enables the explicit n-th order accurate NSE solver to be used with the pressure treatment that is two or four order less accurate without loosing the apparent convergence rate. This feature was not possible with finite volume of finite difference methods. We use Fourier analysis with a model spectrum to determine the condition and found that the range covers standard boundary layer flows. The formal convergence and the performance of the proposed scheme is compared with a sixth-order finite volume method. Finally, the accuracy and performance of the method is evaluated in turbulent channel flows. This work is partially funded by a research colloaboration from IFS, Tohoku university and ASEAN+3 funding scheme from CMUIC, Chiang Mai University.

  12. Comparative Effectiveness of Two Walking Interventions on Participation, Step Counts, and Health.

    Science.gov (United States)

    Smith-McLallen, Aaron; Heller, Debbie; Vernisi, Kristin; Gulick, Diana; Cruz, Samantha; Snyder, Richard L

    2017-03-01

    To (1) compare the effects of two worksite-based walking interventions on employee participation rates; (2) compare average daily step counts between conditions, and; (3) examine the effects of increases in average daily step counts on biometric and psychologic outcomes. We conducted a cluster-randomized trial in which six employer groups were randomly selected and randomly assigned to condition. Four manufacturing worksites and two office-based worksite served as the setting. A total of 474 employees from six employer groups were included. A standard walking program was compared to an enhanced program that included incentives, feedback, competitive challenges, and monthly wellness workshops. Walking was measured by self-reported daily step counts. Survey measures and biometric screenings were administered at baseline and 3, 6, and 9 months after baseline. Analysis used linear mixed models with repeated measures. During 9 months, participants in the enhanced condition averaged 726 more steps per day compared with those in the standard condition (p women (-2.1 lbs.), and reductions in body mass index (-0.41 men, -0.31 women). Higher step counts were also associated with improvements in mood, having more energy, and higher ratings of overall health. An enhanced walking program significantly increases participation rates and daily step counts, which were associated with weight loss and reductions in body mass index.

  13. The Theory and Practice of the Six-Step Method in EFL and Its Transferability to Engineering Programmes

    Science.gov (United States)

    Ntombela, Berrington X. S.

    2013-01-01

    This paper outlines the theory of the six-step method developed by personnel in the Language and Learning department at Caledonian College of Engineering, Oman. The paper further illustrates the application of this method in teaching Project, Listening, Reading, Writing, and Speaking & Debate at Foundation level. The assumption in applying the…

  14. A high-order positivity-preserving single-stage single-step method for the ideal magnetohydrodynamic equations

    Science.gov (United States)

    Christlieb, Andrew J.; Feng, Xiao; Seal, David C.; Tang, Qi

    2016-07-01

    We propose a high-order finite difference weighted ENO (WENO) method for the ideal magnetohydrodynamics (MHD) equations. The proposed method is single-stage (i.e., it has no internal stages to store), single-step (i.e., it has no time history that needs to be stored), maintains a discrete divergence-free condition on the magnetic field, and has the capacity to preserve the positivity of the density and pressure. To accomplish this, we use a Taylor discretization of the Picard integral formulation (PIF) of the finite difference WENO method proposed in Christlieb et al. (2015) [23], where the focus is on a high-order discretization of the fluxes (as opposed to the conserved variables). We use the version where fluxes are expanded to third-order accuracy in time, and for the fluid variables space is discretized using the classical fifth-order finite difference WENO discretization. We use constrained transport in order to obtain divergence-free magnetic fields, which means that we simultaneously evolve the magnetohydrodynamic (that has an evolution equation for the magnetic field) and magnetic potential equations alongside each other, and set the magnetic field to be the (discrete) curl of the magnetic potential after each time step. In this work, we compute these derivatives to fourth-order accuracy. In order to retain a single-stage, single-step method, we develop a novel Lax-Wendroff discretization for the evolution of the magnetic potential, where we start with technology used for Hamilton-Jacobi equations in order to construct a non-oscillatory magnetic field. The end result is an algorithm that is similar to our previous work Christlieb et al. (2014) [8], but this time the time stepping is replaced through a Taylor method with the addition of a positivity-preserving limiter. Finally, positivity preservation is realized by introducing a parameterized flux limiter that considers a linear combination of high and low-order numerical fluxes. The choice of the free

  15. The prediction of the incidence rate of upper limb musculoskeletal disorders, with CTD risk index method on potters of Meybod city

    Directory of Open Access Journals (Sweden)

    Reza Khani Jazani

    2012-02-01

    Full Text Available Background: The objective of this study was to predict the incidence of musculoskeletal disorders in potters of Meybod city by performing CTD risk index method.Materials and Method: This is a descriptive cross-sectional study. Target society was all workers in pottery workshops which were located in the Meybod. Information related to musculoskeletal disorders was obtained by the Nordic questionnaire and we used CTD risk index method to predict the incidence of musculoskeletal disorders.Results: We observed in this study that 59.3% of the potters had symptoms of musculoskeletal disorders in at least in one of their upper extremities. Also significant differences between mean CTD risk index on potters with and without symptoms of the upper limb musculoskeletal disorders, respectively (p=0.038.Conclusion: CTD risk index method can be as a suitable method for predicting the incidence of musculoskeletal disorders used in the potters

  16. Phase gradient algorithm based on co-axis two-step phase-shifting interferometry and its application

    Science.gov (United States)

    Wang, Yawei; Zhu, Qiong; Xu, Yuanyuan; Xin, Zhiduo; Liu, Jingye

    2017-12-01

    A phase gradient method based on co-axis two-step phase-shifting interferometry, is used to reveal the detailed information of a specimen. In this method, the phase gradient distribution can only be obtained by calculating both the first-order derivative and the radial Hilbert transformation of the intensity difference between two phase-shifted interferograms. The feasibility and accuracy of this method were fully verified by the simulation results for a polystyrene sphere and a red blood cell. The empirical results demonstrated that phase gradient is sensitive to changes in the refractive index and morphology. Because phase retrieval and tedious phase unwrapping are not required, the calculation speed is faster. In addition, co-axis interferometry has high spatial resolution.

  17. A comparison principle for an American option on several assets: Index and spread options

    Directory of Open Access Journals (Sweden)

    Peter Laurence

    2003-07-01

    Full Text Available Using the method of symmetrization, we compare the price of the American option on an index or spread to that of the solution of a parabolic variational inequality in one spatial variable. This comparison principle is established for a broad class of diffusion operators with time and state dependent coefficients. The purpose is to take a first step towards deriving symmmetrized problems whose solutions bound solutions of multidimensional American option problems with variable coefficients when the computation of the latter lies beyond the scope of the most powerful numerical methods.

  18. General methods for analysis of sequential "n-step" kinetic mechanisms: application to single turnover kinetics of helicase-catalyzed DNA unwinding.

    Science.gov (United States)

    Lucius, Aaron L; Maluf, Nasib K; Fischer, Christopher J; Lohman, Timothy M

    2003-10-01

    Helicase-catalyzed DNA unwinding is often studied using "all or none" assays that detect only the final product of fully unwound DNA. Even using these assays, quantitative analysis of DNA unwinding time courses for DNA duplexes of different lengths, L, using "n-step" sequential mechanisms, can reveal information about the number of intermediates in the unwinding reaction and the "kinetic step size", m, defined as the average number of basepairs unwound between two successive rate limiting steps in the unwinding cycle. Simultaneous nonlinear least-squares analysis using "n-step" sequential mechanisms has previously been limited by an inability to float the number of "unwinding steps", n, and m, in the fitting algorithm. Here we discuss the behavior of single turnover DNA unwinding time courses and describe novel methods for nonlinear least-squares analysis that overcome these problems. Analytic expressions for the time courses, f(ss)(t), when obtainable, can be written using gamma and incomplete gamma functions. When analytic expressions are not obtainable, the numerical solution of the inverse Laplace transform can be used to obtain f(ss)(t). Both methods allow n and m to be continuous fitting parameters. These approaches are generally applicable to enzymes that translocate along a lattice or require repetition of a series of steps before product formation.

  19. Variable discrete ordinates method for radiation transfer in plane-parallel semi-transparent media with variable refractive index

    Science.gov (United States)

    Sarvari, S. M. Hosseini

    2017-09-01

    The traditional form of discrete ordinates method is applied to solve the radiative transfer equation in plane-parallel semi-transparent media with variable refractive index through using the variable discrete ordinate directions and the concept of refracted radiative intensity. The refractive index are taken as constant in each control volume, such that the direction cosines of radiative rays remain non-variant through each control volume, and then, the directions of discrete ordinates are changed locally by passing each control volume, according to the Snell's law of refraction. The results are compared by the previous studies in this field. Despite simplicity, the results show that the variable discrete ordinate method has a good accuracy in solving the radiative transfer equation in the semi-transparent media with arbitrary distribution of refractive index.

  20. Sensing cocaine in saliva with attenuated total reflection infrared (ATR-IR) spectroscopy combined with a one-step extraction method

    Science.gov (United States)

    Hans, Kerstin M.-C.; Gianella, Michele; Sigrist, Markus W.

    2012-03-01

    On-site drug tests have gained importance, e.g., for protecting the society from impaired drivers. Since today's drug tests are majorly only positive/negative, there is a great need for a reliable, portable and preferentially quantitative drug test. In the project IrSens we aim to bridge this gap with the development of an optical sensor platform based on infrared spectroscopy and focus on cocaine detection in saliva. We combine a one-step extraction method, a sample drying technique and infrared attenuated total reflection (ATR) spectroscopy. As a first step we have developed an extraction technique that allows us to extract cocaine from saliva to an almost infrared-transparent solvent and to record ATR spectra with a commercially available Fourier Transform-infrared spectrometer. To the best of our knowledge this is the first time that such a simple and easy-to-use one-step extraction method is used to transfer cocaine from saliva into an organic solvent and detect it quantitatively. With this new method we are able to reach a current limit of detection around 10 μg/ml. This new extraction method could also be applied to waste water monitoring and controlling caffeine content in beverages.

  1. A novel method to construct an air quality index based on air pollution profiles.

    Science.gov (United States)

    Thach, Thuan-Quoc; Tsang, Hilda; Cao, Peihua; Ho, Lai-Ming

    2018-01-01

    Air quality indices based on the maximum of sub-indices of pollutants are easy to produce and help quantify the degree of air pollution. However, they discount the additive effects of multiple pollutants and are only sensitive to changes in highest sub-index. We propose a simple and concise method to construct an air quality index that takes into account additive effects of multiple pollutants and evaluate the extent to which this index predicts health effects. We obtained concentrations of four criteria pollutants: particulate matter with aerodynamic diameter ≤ 10μm (PM 10 ), sulphur dioxide (SO 2 ), nitrogen dioxide (NO 2 ) and ozone (O 3 ) and daily admissions to Hong Kong hospitals for cardiovascular and respiratory diseases for all ages and those 65 years or older for years 2001-2012. We derived sub-indices of the four criteria pollutants, calculated by normalizing pollutant concentrations to their respective short-term WHO Air Quality Guidelines (WHO AQG). We aggregated the sub-indices using the root-mean-power function with an optimal power to form an overall air quality index. The optimal power was determined by minimizing the sum of over- and under-estimated days. We then assessed associations between the pollution bands of the index and cardiovascular and respiratory admissions using a time-stratified case-crossover design adjusted for ambient temperature, relative humidity and influenza epidemics. Further, we conducted case-crossover analyses using the Hong Kong air quality data with the respective standards and classification of pollution bands of the China Air Quality Index (AQI), the United Kingdom Daily AQI (DAQI), and the United States Environmental Protection Agency (USEPA) AQI. The mean concentrations of PM 10 and SO 2 based on maximum 3-h mean exceeded the WHO AQG by 37% and 50%, respectively. We identified the combined condition of observed high-pollution days as either at least one pollutant > 1.5×WHO AQG or at least two pollutants > 1.0

  2. A review on indexes and dietary assessment methods for determining the quality of diets - doi:10.5020/18061230.2011.p404

    Directory of Open Access Journals (Sweden)

    Ana Carolina Pinheiro Volp

    2012-01-01

    Full Text Available Objective: To summarize the different indexes most frequently used to evaluate the quality of diets, as well as the dietary assessment methods used for scoring, pointing out their advantages and disadvantages. Methods: We performed a literature search, with no date restriction, on primary indexed sources and in the databases SciELO, PubMed, Medline, Lilacs, Dedalus and ILSI Web of Knowledge. The keywords used were diet (ary quality, diet (ary patterns, diet quality index, Mediterranean diet and nutrition. Then, the cited references were reviewed, classifying the information by index. Results: The most widely indexes used are Diet Quality Index, Healthy Eating Index and Alternative Mediterranean Diet Score, using the food frequency questionnaire or a combination of the 24-hour recall and food (s record (s. Conclusion: The determination of feeding patterns through indices is a relatively easy process; however, to have confidence in the results is necessary to know the biases that each index and instrument has, as well as its construction and punctuation.

  3. An iterative method to reconstruct the refractive index of a medium from time-of-flight measurements

    Science.gov (United States)

    Schröder, Udo; Schuster, Thomas

    2016-08-01

    The article deals with a classical inverse problem: the computation of the refractive index of a medium from ultrasound time-of-flight measurements. This problem is very popular in seismics but also for tomographic problems in inhomogeneous media. For example ultrasound vector field tomography needs a priori knowledge of the sound speed. According to Fermat’s principle ultrasound signals travel along geodesic curves of a Riemannian metric which is associated with the refractive index. The inverse problem thus consists of determining the index of refraction from integrals along geodesics curves associated with the integrand leading to a nonlinear problem. In this article we describe a numerical solver for this problem scheme based on an iterative minimization method for an appropriate Tikhonov functional. The outcome of the method is a stable approximation of the sought index of refraction as well as a corresponding set of geodesic curves. We prove some analytical convergence results for this method and demonstrate its performance by means of several numerical experiments. Another novelty in this article is the explicit representation of the backprojection operator for the ray transform in Riemannian geometry and its numerical realization relying on a corresponding phase function that is determined by the metric. This gives a natural extension of the conventional backprojection from 2D computerized tomography to inhomogeneous geometries. The authors dedicate this article to Prof Todd Quinto on the occasion of his 65th birthday.

  4. Influence of the refractive index core profile on modal scattering of terminated two-dimensional waveguides.

    Science.gov (United States)

    Koukoutsaki, Panagiota A; Dasyras, Nikolaos F; Tigelis, Ioannis G; Manenkov, Alexander B; Amditis, Angelos J

    2007-06-01

    We examine the influence of the refractive index core profile on the modal scattering of abruptly terminated slab waveguides. The analysis is based on the integral equation method with accelerating parameters, while for the field description in the waveguide core, an appropriate Lanczos-Fourier expansion is employed. The electric-field distribution on the terminal plane, the reflection and transformation coefficient of the TE guided modes, and the far-field radiation pattern are computed. Numerical results are presented for slab waveguides with step, linear, and parabolic refractive index profiles of the core. Finally, several approximate analytical solutions are derived to study the problem in question and to explain the results obtained.

  5. The Three-Step Test-Interview (TSTI: An observation-based method for pretesting self-completion questionnaires

    Directory of Open Access Journals (Sweden)

    Tony Hak

    2008-12-01

    Full Text Available Three-Step Test-Interview (TSTI is a method for pretesting a self-completion questionnaire by first observing actual instances of interaction between the instrument and respondents (the response process before exploring the reasons for this behavior. The TSTI consists of the following three steps: 1. (Respondent-driven observation of response behavior. 2. (Interviewer-driven follow-up probing aimed at remedying gaps in observational data. 3. (Interviewer-driven debriefing aimed at eliciting experiences and opinions. We describe the aims and the techniques of these three steps, and then discuss pilot studies in which we tested the feasibility and the productivity of the TSTI by applying it in testing three rather different types of questionnaires. In the first study, the quality of a set of questions about alcohol consumption was assessed. The TSTI proved to be productive in identifying problems that resulted from a mismatch between the ‘theory’ underlying the questions on the one hand, and features of a respondent’s actual behavior and biography on the other hand. In the second pilot study, Dutch and Norwegian versions of an attitude scale, the 20-item Illegal Aliens Scale, were tested. The TSTI appeared to be productive in identifying problems that resulted from different ‘response strategies’. In the third pilot, a two-year longitudinal study, the TSTI appeared to be an effective method for documenting processes of ‘response shift’ in repeated measurements of health-related Quality of Life (QoL.

  6. Revision to the humidity correction equation in the calculation formulae of the air refractive index based on a phase step interferometer with three frequency-stabilized lasers

    International Nuclear Information System (INIS)

    Chen, Qianghua; Zhang, Mengce; Liu, Shuaijie; He, Yongxi; Luo, Huifu; Luo, Jun; Lv, Weiwei

    2016-01-01

    At present the formulae proposed by G Boensch and E Potulski in 1998 (Boensch and Potulski 1998 Metrologia 35 133–9) are mostly used to calculate the air refractive index. However, the humidity correction equation in the formulae is derived by using the light source of a Cd lamp whose light frequency stability is poor and at a narrow temperature range, around 20 °C. So it is no longer suitable in present optical precision measurements. To solve this problem, we propose a refractive index measurement system based on phase step interferometer with three frequency stabilized lasers (532 nm, 633 nm, 780 nm), corrected coefficients of the humidity are measured and a corresponding revised humidity correction equation is acquired. Meanwhile, the application temperature range is extended from 14.6 °C to 25.0 °C. The experiment comparison results at the temperature of 22.2–23.2 °C show the accuracy by the presented equation is better than that of Boensch and Potulski. (paper)

  7. Avoid the tsunami of the Dirac sea in the imaginary time step method

    International Nuclear Information System (INIS)

    Zhang, Ying; Liang, Haozhao; Meng, Jie

    2010-01-01

    The discrete single-particle spectra in both the Fermi and Dirac sea have been calculated by the imaginary time step (ITS) method for the Schroedinger-like equation after avoiding the "tsunami" of the Dirac sea, i.e. the diving behavior of the single-particle level into the Dirac sea in the direct application of the ITS method for the Dirac equation. It is found that by the transform from the Dirac equation to the Schroedinger-like equation, the single-particle spectra, which extend from the positive to the negative infinity, can be separately obtained by the ITS evolution in either the Fermi sea or the Dirac sea. Identical results with those in the conventional shooting method have been obtained via the ITS evolution for the equivalent Schroedinger-like equation, which demonstrates the feasibility, practicality and reliability of the present algorithm and dispels the doubts on the ITS method in the relativistic system. (author)

  8. A novel evaluation method for building construction project based on integrated information entropy with reliability theory.

    Science.gov (United States)

    Bai, Xiao-ping; Zhang, Xi-wei

    2013-01-01

    Selecting construction schemes of the building engineering project is a complex multiobjective optimization decision process, in which many indexes need to be selected to find the optimum scheme. Aiming at this problem, this paper selects cost, progress, quality, and safety as the four first-order evaluation indexes, uses the quantitative method for the cost index, uses integrated qualitative and quantitative methodologies for progress, quality, and safety indexes, and integrates engineering economics, reliability theories, and information entropy theory to present a new evaluation method for building construction project. Combined with a practical case, this paper also presents detailed computing processes and steps, including selecting all order indexes, establishing the index matrix, computing score values of all order indexes, computing the synthesis score, sorting all selected schemes, and making analysis and decision. Presented method can offer valuable references for risk computing of building construction projects.

  9. Normal Values of Tissue-Muscle Perfusion Indexes of Lower Limbs Obtained with a Scintigraphic Method.

    Science.gov (United States)

    Manevska, Nevena; Stojanoski, Sinisa; Pop Gjorceva, Daniela; Todorovska, Lidija; Miladinova, Daniela; Zafirova, Beti

    2017-09-01

    Introduction Muscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes and perfusion reserve. The investigation of the microcirculation has a crucial role in determining the muscle perfusion. Materials and method The study included 30 examinees, 24-74 years of age, without a history of confirmed peripheral artery disease and all had normal findings on Doppler ultrasonography and pedo-brachial index of lower extremity (PBI). 99mTc-MIBI tissue muscle perfusion scintigraphy of lower limbs evaluates tissue perfusion in resting condition "rest study" and after workload "stress study", through quantitative parameters: Inter-extremity index (for both studies), left thigh/right thigh (LT/RT) left calf/right calf (LC/RC) and perfusion reserve (PR) for both thighs and calves. Results In our investigated group we assessed the normal values of quantitative parameters of perfusion indexes. Indexes ranged for LT/RT in rest study 0.91-1.05, in stress study 0.92-1.04. LC/RC in rest 0.93-1.07 and in stress study 0.93-1.09. The examinees older than 50 years had insignificantly lower perfusion reserve of these parameters compared with those younger than 50, LC (p=0.98), and RC (p=0.6). Conclusion This non-invasive scintigraphic method allows in individuals without peripheral artery disease to determine the range of normal values of muscle perfusion at rest and stress condition and to clinically implement them in evaluation of patients with peripheral artery disease for differentiating patients with normal from those with impaired lower limbs circulation.

  10. Ankle-brachial index by automated method and renal function

    Directory of Open Access Journals (Sweden)

    Ricardo Pereira Silva

    2017-05-01

    Full Text Available Background The Ankle-brachial index (ABI is a non-invasive method used for the diagnosis of peripheral arterial occlusive disease (PAOD. Aims To determine the clinical features of patients submitted to ABI measurement by automatic method. To investigate association between ABI and renal function. Methods The present is a cross-sectional study. The study was performed in a private clinic in the city of Fortaleza (Ce- Brazil. For ABI analysis, we utilized automatic methodology using a Microlife device. Data collection took place from March 2012 to January 2016. During this period, ABI was measured in 375 patients aged >50 years, who had a diagnosis of hypertension, diabetes or vascular disease. Results Of the 375 patients, 18 were categorized as having abnormal ABI (4.8 per cent and 357 were normal ABI (95.2 per cent. Patients with abnormal ABI showed older mean age when compared to patients with normal ABI. Among patients with normal renal function, only 0.95 per cent showed abnormal ABI; among patients with abnormal renal function, 6 per cent showed abnormal ABI. Conclusion 1 No differences were observed when comparing the groups regarding gender or the prevalence of hypertension, diabetes, dyslipidaemia or CAD. 2 Group with abnormal ABI had renal function greater impairment.

  11. Determining the multi-scale hedge ratios of stock index futures using the lower partial moments method

    Science.gov (United States)

    Dai, Jun; Zhou, Haigang; Zhao, Shaoquan

    2017-01-01

    This paper considers a multi-scale future hedge strategy that minimizes lower partial moments (LPM). To do this, wavelet analysis is adopted to decompose time series data into different components. Next, different parametric estimation methods with known distributions are applied to calculate the LPM of hedged portfolios, which is the key to determining multi-scale hedge ratios over different time scales. Then these parametric methods are compared with the prevailing nonparametric kernel metric method. Empirical results indicate that in the China Securities Index 300 (CSI 300) index futures and spot markets, hedge ratios and hedge efficiency estimated by the nonparametric kernel metric method are inferior to those estimated by parametric hedging model based on the features of sequence distributions. In addition, if minimum-LPM is selected as a hedge target, the hedging periods, degree of risk aversion, and target returns can affect the multi-scale hedge ratios and hedge efficiency, respectively.

  12. Synthesis and photocatalytic application of α-Fe2O3/ZnO fine particles prepared by two-step chemical method

    Directory of Open Access Journals (Sweden)

    Patij Shah

    2013-06-01

    Full Text Available Composite iron oxide-Zinc oxide (α-Fe2O3/ZnO was synthesized by two-step method: in the first one step uniform α-Fe2O3 particles were prepared through a hydrolysis process of ferric chloride at 80 °C. In the second step, the ZnO particles were included in the α-Fe2O3 particles by a zinc acetate [Zn(Ac2·2H2O] assisted hydrothermal method at low temperature (90°C±C. The α-Fe2O3 and ZnO phases were identified by XRD, energy dispersive X-ray analysis (EDX. The photoreactivities of α-Fe2O3/ZnO nanoparticles under UV irradiation were quantified by the degradation of formaldehyde.

  13. A 10-step safety management framework for construction small and medium-sized enterprises.

    Science.gov (United States)

    Gunduz, Murat; Laitinen, Heikki

    2017-09-01

    It is of great importance to develop an occupational health and safety management system (OHS MS) to form a systemized approach to improve health and safety. It is a known fact that thousands of accidents and injuries occur in the construction industry. Most of these accidents occur in small and medium-sized enterprises (SMEs). This article provides a 10-step user-friendly OHS MS for the construction industry. A quantitative OHS MS indexing method is also introduced in the article. The practical application of the system to real SMEs and its promising results are also presented.

  14. A Renormalisation Group Method. V. A Single Renormalisation Group Step

    Science.gov (United States)

    Brydges, David C.; Slade, Gordon

    2015-05-01

    This paper is the fifth in a series devoted to the development of a rigorous renormalisation group method applicable to lattice field theories containing boson and/or fermion fields, and comprises the core of the method. In the renormalisation group method, increasingly large scales are studied in a progressive manner, with an interaction parametrised by a field polynomial which evolves with the scale under the renormalisation group map. In our context, the progressive analysis is performed via a finite-range covariance decomposition. Perturbative calculations are used to track the flow of the coupling constants of the evolving polynomial, but on their own perturbative calculations are insufficient to control error terms and to obtain mathematically rigorous results. In this paper, we define an additional non-perturbative coordinate, which together with the flow of coupling constants defines the complete evolution of the renormalisation group map. We specify conditions under which the non-perturbative coordinate is contractive under a single renormalisation group step. Our framework is essentially combinatorial, but its implementation relies on analytic results developed earlier in the series of papers. The results of this paper are applied elsewhere to analyse the critical behaviour of the 4-dimensional continuous-time weakly self-avoiding walk and of the 4-dimensional -component model. In particular, the existence of a logarithmic correction to mean-field scaling for the susceptibility can be proved for both models, together with other facts about critical exponents and critical behaviour.

  15. Research on the Selection Strategy of Green Building Parts Supplier Based on the Catastrophe Theory and Kent Index Method

    Directory of Open Access Journals (Sweden)

    Zhenhua Luo

    2016-01-01

    Full Text Available At present, the green building and housing industrialization are two mainstream directions in the real estate industry. The production of green building parts which combines green building and housing industrialization, two concepts, is to be vigorously developed. The key of quality assurance in the assembly project is choosing reliable and proper green building parts suppliers. This paper analyzes the inherent requirements of the green building, combined with the characteristics of the housing industrialization, and puts forward an evaluation index system of supplier selection for green building parts, which includes product index, enterprise index, green development index, and cooperation ability index. To reduce the influence of subjective factors, the improved method which merges Kent index method and catastrophe theory is applied to the green building parts supplier selection and evaluation. This paper takes the selection of the unit bathroom suppliers as an example, uses the improved model to calculate and analyze the data of each supplier, and finally selects the optimal supplier. With combination of the Kent index and the catastrophe theory, the result shows that it can effectively reduce the subjectivity of the evaluation and provide a basis for the selection of the green building parts suppliers.

  16. Two-step design method for highly compact three-dimensional freeform optical system for LED surface light source.

    Science.gov (United States)

    Mao, Xianglong; Li, Hongtao; Han, Yanjun; Luo, Yi

    2014-10-20

    Designing an illumination system for a surface light source with a strict compactness requirement is quite challenging, especially for the general three-dimensional (3D) case. In accordance with the two key features of an expected illumination distribution, i.e., a well-controlled boundary and a precise illumination pattern, a two-step design method is proposed in this paper for highly compact 3D freeform illumination systems. In the first step, a target shape scaling strategy is combined with an iterative feedback modification algorithm to generate an optimized freeform optical system with a well-controlled boundary of the target distribution. In the second step, a set of selected radii of the system obtained in the first step are optimized to further improve the illuminating quality within the target region. The method is quite flexible and effective to design highly compact optical systems with almost no restriction on the shape of the desired target field. As examples, three highly compact freeform lenses with ratio of center height h of the lens and the maximum dimension D of the source ≤ 2.5:1 are designed for LED surface light sources to form a uniform illumination distribution on a rectangular, a cross-shaped and a complex cross pierced target plane respectively. High light control efficiency of η > 0.7 as well as low relative standard illumination deviation of RSD < 0.07 is obtained simultaneously for all the three design examples.

  17. SiO2 sol-gel films after ammonia and heat two-step treatments

    International Nuclear Information System (INIS)

    Zhang Chunlai; Wang Biyi; Tian Dongbin; Yin Wei; Jiang Xiaodong; Yuan Xiaodong; Yan Lianghong; Zhang Hongliang; Zhao Songnan; Lv Haibing

    2008-01-01

    SiO 2 thin films were deposited using tetraethoxylsilane as precursor, ammonia as catalyst on K9 glass by sol-gel method. These films were post-treated by ammonia and heat. The properties of the coatings were characterized by ellipsometer, UV-vis spectrophotometry, FTIR-spectroscopy, scanning probe microscope and contact angle measurement apparatus. The resuits indicate that the thickness of the films with ammonia and heat treatment tend to decrease. Both the refractive index and water contact angle increase after ammonia treatment. However, they both decrease after heat treatment. The former increases by 0.236 for the first step, then decreases by 0.202 for the second. The latter increases to 58.92 degree, then decreases to 38.07 degree. The transmittance of the coatings turn to be better and continuously shift to short wave by UV-vis spectrophotometry. The surface becomes smoother by AFM after the two-step treatment. (authors)

  18. A GPU-accelerated semi-implicit fractional step method for numerical solutions of incompressible Navier-Stokes equations

    Science.gov (United States)

    Ha, Sanghyun; Park, Junshin; You, Donghyun

    2017-11-01

    Utility of the computational power of modern Graphics Processing Units (GPUs) is elaborated for solutions of incompressible Navier-Stokes equations which are integrated using a semi-implicit fractional-step method. Due to its serial and bandwidth-bound nature, the present choice of numerical methods is considered to be a good candidate for evaluating the potential of GPUs for solving Navier-Stokes equations using non-explicit time integration. An efficient algorithm is presented for GPU acceleration of the Alternating Direction Implicit (ADI) and the Fourier-transform-based direct solution method used in the semi-implicit fractional-step method. OpenMP is employed for concurrent collection of turbulence statistics on a CPU while Navier-Stokes equations are computed on a GPU. Extension to multiple NVIDIA GPUs is implemented using NVLink supported by the Pascal architecture. Performance of the present method is experimented on multiple Tesla P100 GPUs compared with a single-core Xeon E5-2650 v4 CPU in simulations of boundary-layer flow over a flat plate. Supported by the National Research Foundation of Korea (NRF) Grant funded by the Korea government (Ministry of Science, ICT and Future Planning NRF-2016R1E1A2A01939553, NRF-2014R1A2A1A11049599, and Ministry of Trade, Industry and Energy 201611101000230).

  19. Variable Step Integration Coupled with the Method of Characteristics Solution for Water-Hammer Analysis, A Case Study

    Science.gov (United States)

    Turpin, Jason B.

    2004-01-01

    One-dimensional water-hammer modeling involves the solution of two coupled non-linear hyperbolic partial differential equations (PDEs). These equations result from applying the principles of conservation of mass and momentum to flow through a pipe, and usually the assumption that the speed at which pressure waves propagate through the pipe is constant. In order to solve these equations for the interested quantities (i.e. pressures and flow rates), they must first be converted to a system of ordinary differential equations (ODEs) by either approximating the spatial derivative terms with numerical techniques or using the Method of Characteristics (MOC). The MOC approach is ideal in that no numerical approximation errors are introduced in converting the original system of PDEs into an equivalent system of ODEs. Unfortunately this resulting system of ODEs is bound by a time step constraint so that when integrating the equations the solution can only be obtained at fixed time intervals. If the fluid system to be modeled also contains dynamic components (i.e. components that are best modeled by a system of ODEs), it may be necessary to take extremely small time steps during certain points of the model simulation in order to achieve stability and/or accuracy in the solution. Coupled together, the fixed time step constraint invoked by the MOC, and the occasional need for extremely small time steps in order to obtain stability and/or accuracy, can greatly increase simulation run times. As one solution to this problem, a method for combining variable step integration (VSI) algorithms with the MOC was developed for modeling water-hammer in systems with highly dynamic components. A case study is presented in which reverse flow through a dual-flapper check valve introduces a water-hammer event. The predicted pressure responses upstream of the check-valve are compared with test data.

  20. Analysis of beam propagation characteristics in gain-guided, index antiguided fibers with the beam propagation method.

    Science.gov (United States)

    Ai, Fei; Qian, Jianqiang; Shi, Junfeng; Zhang, Machi

    2017-10-10

    The transmission properties of beams in gain fibers are studied with the complex refractive index beam propagation method (CRI-BPM). The method is checked by comparison with an analytic method. The behavior of a gain-guided, index antiguided (GG-IAG) fiber with different gain coefficients is studied. The simulation results show that the signal can transfer in the fiber with almost no loss when the gain coefficient reaches the threshold of the fundamental mode, and the shape of output spot will have no major changes when the gain coefficient is over the thresholds of high-order modes, even when the mode competition is not obvious. The CRI-BPM can predict the changes in light power and light mode at the same time, and will be very useful in the designing of fiber amplifiers and lasers with complex structures. More factors will be considered in this method to provide reference for practical application in our further research.

  1. A probabilistic method for computing quantitative risk indexes from medical injuries compensation claims.

    Science.gov (United States)

    Dalle Carbonare, S; Folli, F; Patrini, E; Giudici, P; Bellazzi, R

    2013-01-01

    The increasing demand of health care services and the complexity of health care delivery require Health Care Organizations (HCOs) to approach clinical risk management through proper methods and tools. An important aspect of risk management is to exploit the analysis of medical injuries compensation claims in order to reduce adverse events and, at the same time, to optimize the costs of health insurance policies. This work provides a probabilistic method to estimate the risk level of a HCO by computing quantitative risk indexes from medical injury compensation claims. Our method is based on the estimate of a loss probability distribution from compensation claims data through parametric and non-parametric modeling and Monte Carlo simulations. The loss distribution can be estimated both on the whole dataset and, thanks to the application of a Bayesian hierarchical model, on stratified data. The approach allows to quantitatively assessing the risk structure of the HCO by analyzing the loss distribution and deriving its expected value and percentiles. We applied the proposed method to 206 cases of injuries with compensation requests collected from 1999 to the first semester of 2007 by the HCO of Lodi, in the Northern part of Italy. We computed the risk indexes taking into account the different clinical departments and the different hospitals involved. The approach proved to be useful to understand the HCO risk structure in terms of frequency, severity, expected and unexpected loss related to adverse events.

  2. Effect of the refractive index on the hawking temperature: an application of the Hamilton-Jacobi method

    Science.gov (United States)

    Sakalli, I.; Mirekhtiary, S. F.

    2013-10-01

    Hawking radiation of a non-asymptotically flat 4-dimensional spherically symmetric and static dilatonic black hole (BH) via the Hamilton-Jacobi (HJ) method is studied. In addition to the naive coordinates, we use four more different coordinate systems that are well-behaved at the horizon. Except for the isotropic coordinates, direct computation by the HJ method leads to the standard Hawking temperature for all coordinate systems. The isotropic coordinates allow extracting the index of refraction from the Fermat metric. It is explicitly shown that the index of refraction determines the value of the tunneling rate and its natural consequence, the Hawking temperature. The isotropic coordinates in the conventional HJ method produce a wrong result for the temperature of the linear dilaton. Here, we explain how this discrepancy can be resolved by regularizing the integral possessing a pole at the horizon.

  3. Effect of the refractive index on the hawking temperature: an application of the Hamilton-Jacobi method

    Energy Technology Data Exchange (ETDEWEB)

    Sakalli, I., E-mail: izzet.sakalli@emu.edu.tr; Mirekhtiary, S. F., E-mail: fatemeh.mirekhtiary@emu.edu.tr [Eastern Mediterranean University G. Magosa, Department of Physics (Turkey)

    2013-10-15

    Hawking radiation of a non-asymptotically flat 4-dimensional spherically symmetric and static dilatonic black hole (BH) via the Hamilton-Jacobi (HJ) method is studied. In addition to the naive coordinates, we use four more different coordinate systems that are well-behaved at the horizon. Except for the isotropic coordinates, direct computation by the HJ method leads to the standard Hawking temperature for all coordinate systems. The isotropic coordinates allow extracting the index of refraction from the Fermat metric. It is explicitly shown that the index of refraction determines the value of the tunneling rate and its natural consequence, the Hawking temperature. The isotropic coordinates in the conventional HJ method produce a wrong result for the temperature of the linear dilaton. Here, we explain how this discrepancy can be resolved by regularizing the integral possessing a pole at the horizon.

  4. Identification method of non-reflective faults based on index distribution of optical fibers.

    Science.gov (United States)

    Lee, Wonkyoung; Myong, Seung Il; Lee, Jyung Chan; Lee, Sangsoo

    2014-01-13

    This paper investigates an identification method of non-reflective faults based on index distribution of optical fibers. The method identifies not only reflective faults but also non-reflective faults caused by tilted fiber-cut, lateral connector-misalignment, fiber-bend, and temperature variation. We analyze the reason why wavelength dependence of the fiber-bend is opposite to that of the lateral connector-misalignment, and the effect of loss due to temperature variation on OTDR waveforms through simulation and experimental results. This method can be realized by only upgrade of fault-analysis software without the hardware change, it is, therefore, competitive and cost-effective in passive optical networks.

  5. A NEW MULTI-SPECTRAL THRESHOLD NORMALIZED DIFFERENCE WATER INDEX (MST-NDWI WATER EXTRACTION METHOD – A CASE STUDY IN YANHE WATERSHED

    Directory of Open Access Journals (Sweden)

    Y. Zhou

    2018-05-01

    Full Text Available Accurate remote sensing water extraction is one of the primary tasks of watershed ecological environment study. Since the Yanhe water system has typical characteristics of a small water volume and narrow river channel, which leads to the difficulty for conventional water extraction methods such as Normalized Difference Water Index (NDWI. A new Multi-Spectral Threshold segmentation of the NDWI (MST-NDWI water extraction method is proposed to achieve the accurate water extraction in Yanhe watershed. In the MST-NDWI method, the spectral characteristics of water bodies and typical backgrounds on the Landsat/TM images have been evaluated in Yanhe watershed. The multi-spectral thresholds (TM1, TM4, TM5 based on maximum-likelihood have been utilized before NDWI water extraction to realize segmentation for a division of built-up lands and small linear rivers. With the proposed method, a water map is extracted from the Landsat/TM images in 2010 in China. An accuracy assessment is conducted to compare the proposed method with the conventional water indexes such as NDWI, Modified NDWI (MNDWI, Enhanced Water Index (EWI, and Automated Water Extraction Index (AWEI. The result shows that the MST-NDWI method generates better water extraction accuracy in Yanhe watershed and can effectively diminish the confusing background objects compared to the conventional water indexes. The MST-NDWI method integrates NDWI and Multi-Spectral Threshold segmentation algorithms, with richer valuable information and remarkable results in accurate water extraction in Yanhe watershed.

  6. Dose Rate Experiment at JET for Benchmarking the Calculation Direct One Step Method

    International Nuclear Information System (INIS)

    Angelone, M.; Petrizzi, L.; Pillon, M.; Villari, R.; Popovichev, S.

    2006-01-01

    Neutrons produced by D-D and D-T plasmas induce the activation of tokamak materials and of components. The development of reliable methods to assess dose rates is a key issue for maintenance and operating nuclear machines, in normal and off-normal conditions. In the frame of the EFDA Fusion Technology work programme, a computational tool based upon MCNP Monte Carlo code has been developed to predict the dose rate after shutdown: it is called Direct One Step Method (D1S). The D1S is an innovative approach in which the decay gammas are coupled to the neutrons as in the prompt case and they are transported in one single step in the same run. Benchmarking of this new tool with experimental data taken in a complex geometry like that of a tokamak is a fundamental step to test the reliability of the D1S method. A dedicated benchmark experiment was proposed for the 2005-2006 experimental campaign of JET. Two irradiation positions have been selected for the benchmark: one inner position inside the vessel, not far from the plasma, called the 2 upper irradiation end (IE2), where neutron fluence is relatively high. The second position is just outside a vertical port in an external position (EX). Here the neutron flux is lower and the dose rate to be measured is not very far from the residual background. Passive detectors are used for in-vessel measurements: the high sensitivity Thermo Luminescent Dosimeters (TLDs) GR-200A (natural LiF), which ensure measurements down to environmental dose level. An active detector of Geiger-Muller (GM) type is used for out of vessel dose rate measurement. Before their use the detectors were calibrated in a secondary gamma-ray standard (Cs-137 and Co-60) facility in term of air-kerma. The background measurement was carried-out in the period July -September 2005 in the outside position EX using the GM tube and in September 2005 inside the vacuum vessel using TLD detectors located in the 2 Upper irradiation end IE2. In the present work

  7. Step-to-step variability in treadmill walking: influence of rhythmic auditory cueing.

    Directory of Open Access Journals (Sweden)

    Philippe Terrier

    Full Text Available While walking, human beings continuously adjust step length (SpL, step time (SpT, step speed (SpS = SpL/SpT and step width (SpW by integrating both feedforward and feedback mechanisms. These motor control processes result in correlations of gait parameters between consecutive strides (statistical persistence. Constraining gait with a speed cue (treadmill and/or a rhythmic auditory cue (metronome, modifies the statistical persistence to anti-persistence. The objective was to analyze whether the combined effect of treadmill and rhythmic auditory cueing (RAC modified not only statistical persistence, but also fluctuation magnitude (standard deviation, SD, and stationarity of SpL, SpT, SpS and SpW. Twenty healthy subjects performed 6 × 5 min. walking tests at various imposed speeds on a treadmill instrumented with foot-pressure sensors. Freely-chosen walking cadences were assessed during the first three trials, and then imposed accordingly in the last trials with a metronome. Fluctuation magnitude (SD of SpT, SpL, SpS and SpW was assessed, as well as NonStationarity Index (NSI, which estimates the dispersion of local means in the times series (SD of 20 local means over 10 steps. No effect of RAC on fluctuation magnitude (SD was observed. SpW was not modified by RAC, what is likely the evidence that lateral foot placement is separately regulated. Stationarity (NSI was modified by RAC in the same manner as persistent pattern: Treadmill induced low NSI in the time series of SpS, and high NSI in SpT and SpL. On the contrary, SpT, SpL and SpS exhibited low NSI under RAC condition. We used relatively short sample of consecutive strides (100 as compared to the usual number of strides required to analyze fluctuation dynamics (200 to 1000 strides. Therefore, the responsiveness of stationarity measure (NSI to cued walking opens the perspective to perform short walking tests that would be adapted to patients with a reduced gait perimeter.

  8. Proposal of an environmental performance index to assess solid waste treatment technologies

    International Nuclear Information System (INIS)

    Goulart Coelho, Hosmanny Mauro; Lange, Liséte Celina; Coelho, Lineker Max Goulart

    2012-01-01

    Highlights: ► Proposal of a new concept in waste management: Cleaner Treatment. ► Development of an index to assess quantitatively waste treatment technologies. ► Delphi Method was carried out so as to define environmental indicators. ► Environmental performance evaluation of waste-to-energy plants. - Abstract: Although the concern with sustainable development and environment protection has considerably grown in the last years it is noted that the majority of decision making models and tools are still either excessively tied to economic aspects or geared to the production process. Moreover, existing models focus on the priority steps of solid waste management, beyond waste energy recovery and disposal. So, in order to help the lack of models and tools aiming at the waste treatment and final disposal, a new concept is proposed: the Cleaner Treatment, which is based on the Cleaner Production principles. This paper focuses on the development and validation of the Cleaner Treatment Index (CTI), to assess environmental performance of waste treatment technologies based on the Cleaner Treatment concept. The index is formed by aggregation (summation or product) of several indicators that consists in operational parameters. The weights of the indicator were established by Delphi Method and Brazilian Environmental Laws. In addition, sensitivity analyses were carried out comparing both aggregation methods. Finally, index validation was carried out by applying the CTI to 10 waste-to-energy plants data. From sensitivity analysis and validation results it is possible to infer that summation model is the most suitable aggregation method. For summation method, CTI results were superior to 0.5 (in a scale from 0 to 1) for most facilities evaluated. So, this study demonstrates that CTI is a simple and robust tool to assess and compare the environmental performance of different treatment plants being an excellent quantitative tool to support Cleaner Treatment implementation.

  9. A step in the right direction: new flow depth relationships for stepped spillway design

    Science.gov (United States)

    A common deficiency for embankment dams changing from a low hazard to a high hazard dam is inadequate spillway capacity. Roller compacted concrete (RCC) stepped spillways are a popular method to address this issue. Stepped spillway research has gained momentum in recent years due to the need for d...

  10. Linked data querying through FCA-based schema indexing

    OpenAIRE

    Brosius, Dominik; Staab, Steffen

    2016-01-01

    The effciency of SPARQL query evaluation against Linked Open Data may benefit from schema-based indexing. However, many data items come with incomplete schema information or lack schema descriptions entirely. In this position paper, we outline an approach to an indexing of linked data graphs based on schemata induced through Formal Concept Analysis. We show how to map queries onto RDF graphs based on such derived schema information. We sketch next steps for realizing and optimizing the sugges...

  11. A Novel Evaluation Method for Building Construction Project Based on Integrated Information Entropy with Reliability Theory

    Directory of Open Access Journals (Sweden)

    Xiao-ping Bai

    2013-01-01

    Full Text Available Selecting construction schemes of the building engineering project is a complex multiobjective optimization decision process, in which many indexes need to be selected to find the optimum scheme. Aiming at this problem, this paper selects cost, progress, quality, and safety as the four first-order evaluation indexes, uses the quantitative method for the cost index, uses integrated qualitative and quantitative methodologies for progress, quality, and safety indexes, and integrates engineering economics, reliability theories, and information entropy theory to present a new evaluation method for building construction project. Combined with a practical case, this paper also presents detailed computing processes and steps, including selecting all order indexes, establishing the index matrix, computing score values of all order indexes, computing the synthesis score, sorting all selected schemes, and making analysis and decision. Presented method can offer valuable references for risk computing of building construction projects.

  12. APPLICATION OF THE PERFORMANCE SELECTION INDEX METHOD FOR SOLVING MACHINING MCDM PROBLEMS

    Directory of Open Access Journals (Sweden)

    Dušan Petković

    2017-04-01

    Full Text Available Complex nature of machining processes requires the use of different methods and techniques for process optimization. Over the past few years a number of different optimization methods have been proposed for solving continuous machining optimization problems. In manufacturing environment, engineers are also facing a number of discrete machining optimization problems. In order to help decision makers in solving this type of optimization problems a number of multi criteria decision making (MCDM methods have been proposed. This paper introduces the use of an almost unexplored MCDM method, i.e. performance selection index (PSI method for solving machining MCDM problems. The main motivation for using the PSI method is that it is not necessary to determine criteria weights as in other MCDM methods. Applicability and effectiveness of the PSI method have been demonstrated while solving two case studies dealing with machinability of materials and selection of the most suitable cutting fluid for the given machining application. The obtained rankings have good correlation with those derived by the past researchers using other MCDM methods which validate the usefulness of this method for solving machining MCDM problems.

  13. In situ synthesis carbonated hydroxyapatite layers on enamel slices with acidic amino acids by a novel two-step method.

    Science.gov (United States)

    Wu, Xiaoguang; Zhao, Xu; Li, Yi; Yang, Tao; Yan, Xiujuan; Wang, Ke

    2015-09-01

    In situ fabrication of carbonated hydroxyapatite (CHA) remineralization layer on an enamel slice was completed in a novel, biomimetic two-step method. First, a CaCO3 layer was synthesized on the surface of demineralized enamel using an acidic amino acid (aspartic acid or glutamate acid) as a soft template. Second, at the same concentration of the acidic amino acid, rod-like carbonated hydroxyapatite was produced with the CaCO3 layer as a sacrificial template and a reactant. The morphology, crystallinity and other physicochemical properties of the crystals were characterized using field emission scanning electron microscopy (FESEM), Fourier transform infrared spectrometry (FTIR), X-ray diffraction (XRD) and energy-dispersive X-ray analysis (EDAX), respectively. Acidic amino acid could promote the uniform deposition of hydroxyapatite with rod-like crystals via absorption of phosphate and carbonate ions from the reaction solution. Moreover, compared with hydroxyapatite crystals coated on the enamel when synthesized by a one-step method, the CaCO3 coating that was synthesized in the first step acted as an active bridge layer and sacrificial template. It played a vital role in orienting the artificial coating layer through the template effect. The results show that the rod-like carbonated hydroxyapatite crystals grow into bundles, which are similar in size and appearance to prisms in human enamel, when using the two-step method with either aspartic acid or acidic glutamate (20.00 mmol/L). Copyright © 2015 Elsevier B.V. All rights reserved.

  14. An alternative method to determine the refractive index of Al{sub x}Ga{sub 1−x}N

    Energy Technology Data Exchange (ETDEWEB)

    Engelbrecht, J.A.A., E-mail: Japie.Engelbrecht@nmmu.ac.za [Physics Department, NMMU, Port Elizabeth (South Africa); HRTEM Facility, NMMU, Port Elizabeth (South Africa); Sephton, B. [Physics Department, NMMU, Port Elizabeth (South Africa); Minnaar, E. [HRTEM Facility, NMMU, Port Elizabeth (South Africa); Wagener, M.C. [Physics Department, NMMU, Port Elizabeth (South Africa)

    2016-01-01

    Certain characterizations of Al{sub x}Ga{sub 1−x}N epilayers require knowledge of the refractive index. Four theoretical models are reviewed, and a simple method to obtain the refractive index n of Al{sub x}Ga{sub 1−x}N is proposed. Values of the refractive index obtained at various wavelengths and Al concentrations are compared to the theoretical models, as well as to previously obtained experimental results. Acceptable agreement with both theoretical and experimental values are obtained.

  15. ONE-STEP AND TWO-STEP CALIBRATION OF A PORTABLE PANORAMIC IMAGE MAPPING SYSTEM

    Directory of Open Access Journals (Sweden)

    P.-C. Wang

    2012-07-01

    Full Text Available A Portable Panoramic Image Mapping System (PPIMS is proposed for rapid acquisition of three-dimensional spatial information. By considering the convenience of use, cost, weight of equipment, precision, and power supply, the designed PPIMS is equipped with 6 circularly arranged cameras to capture panoramic images and a GPS receiver for positioning. The motivation for this design is to develop a hand-held Mobile Mapping System (MMS for some difficult accessing areas by vehicle MMS, such as rugged terrains, forest areas, heavily damaged disaster areas, and crowed places etc. This PPIMS is in fact a GPS assisted close-range photogrammetric system. Compared with the traditional close-range photogrammetry, PPIMS can reduce the need of ground control points significantly. Under the condition of knowing the relative geometric relationships of the equipped sensors, the elements of exterior orientation of each captured image can be solved. However, the procedure of a system calibration should be done accurately to determine the relative geometric relationships of multi-cameras and the GPS antenna center, before the PPIMS can be applied for geo-referenced mapping. In this paper, both of one-step and two-step calibration procedures for PPIMS are performed to determine the lever-arm offsets and boresight angles among cameras and GPS. The performance of the one-step and two-step calibration is evaluated through the analysis of the experimental results. The comparison between these two calibration procedures was also conducted. The two-step calibration method outperforms the one-step calibration method in terms of calibration accuracy and operation convenience. We expect that the proposed two-step calibration procedure can also be applied to other platform-based MMSs.

  16. 2-Step IMAT and 2-Step IMRT in three dimensions

    International Nuclear Information System (INIS)

    Bratengeier, Klaus

    2005-01-01

    In two dimensions, 2-Step Intensity Modulated Arc Therapy (2-Step IMAT) and 2-Step Intensity Modulated Radiation Therapy (IMRT) were shown to be powerful methods for the optimization of plans with organs at risk (OAR) (partially) surrounded by a target volume (PTV). In three dimensions, some additional boundary conditions have to be considered to establish 2-Step IMAT as an optimization method. A further aim was to create rules for ad hoc adaptations of an IMRT plan to a daily changing PTV-OAR constellation. As a test model, a cylindrically symmetric PTV-OAR combination was used. The centrally placed OAR can adapt arbitrary diameters with different gap widths toward the PTV. Along the rotation axis the OAR diameter can vary, the OAR can even vanish at some axis positions, leaving a circular PTV. The width and weight of the second segment were the free parameters to optimize. The objective function f to minimize was the root of the integral of the squared difference of the dose in the target volume and a reference dose. For the problem, two local minima exist. Therefore, as a secondary criteria, the magnitude of hot and cold spots were taken into account. As a result, the solution with a larger segment width was recommended. From plane to plane for varying radii of PTV and OAR and for different gaps between them, different sets of weights and widths were optimal. Because only one weight for one segment shall be used for all planes (respectively leaf pairs), a strategy for complex three-dimensional (3-D) cases was established to choose a global weight. In a second step, a suitable segment width was chosen, minimizing f for this global weight. The concept was demonstrated in a planning study for a cylindrically symmetric example with a large range of different radii of an OAR along the patient axis. The method is discussed for some classes of tumor/organ at risk combinations. Noncylindrically symmetric cases were treated exemplarily. The product of width and weight of

  17. A novel single-step, multipoint calibration method for instrumented Lab-on-Chip systems

    DEFF Research Database (Denmark)

    Pfreundt, Andrea; Patou, François; Zulfiqar, Azeem

    2014-01-01

    for instrument-based PoC blood biomarker analysis systems. Motivated by the complexity of associating high-accuracy biosensing using silicon nanowire field effect transistors with ease of use for the PoC system user, we propose a novel one-step, multipoint calibration method for LoC-based systems. Our approach...... specifically addresses the important interfaces between a novel microfluidic unit to integrate the sensor array and a mobile-device hardware accessory. A multi-point calibration curve is obtained by generating a defined set of reference concentrations from a single input. By consecutively splitting the flow...

  18. Center index method-an alternative for wear measurements with radiostereometry (RSA).

    Science.gov (United States)

    Dahl, Jon; Figved, Wender; Snorrason, Finnur; Nordsletten, Lars; Röhrl, Stephan M

    2013-03-01

    Radiostereometry (RSA) is considered to be the most precise and accurate method for wear-measurements in total hip replacement. Post-operative stereoradiographs has so far been necessary for wear measurement. Hence, the use of RSA has been limited to studies planned for RSA measurements. We compared a new RSA method for wear measurements that does not require previous radiographs with conventional RSA. Instead of comparing present stereoradiographs with post-operative ones, we developed a method for calculating the post-operative position of the center of the femoral head on the present examination and using this as the index measurement. We compared this alternative method to conventional RSA in 27 hips in an ongoing RSA study. We found a high degree of agreement between the methods for both mean proximal (1.19 mm vs. 1.14 mm) and mean 3D wear (1.52 mm vs. 1.44 mm) after 10 years. Intraclass correlation coefficients (ICC) were 0.958 and 0.955, respectively (pRSA offers comparable results to conventional RSA measurements. It allows precise wear measurements without previous radiological examinations. Copyright © 2012 Orthopaedic Research Society.

  19. Quality Index Method (QIM) scheme developed for farmed Atlantic salmon ( Salmo salar )

    DEFF Research Database (Denmark)

    Sveinsdóttir, K.; Hyldig, Grethe; Martinsdóttir, E.

    2003-01-01

    The aim of the study was to develop 'Quality Index Method (QIM) scheme for raw, farmed Atlantic salmon (Salmo salar) and to evaluate the scheme. in a shelf life study. QIM is based on the evaluation of key parameters in the deterioration of seafood's. Demerit points are assigned to selected...... parameters according to their importance and a Quality Index (QI) is established by cumulating the resulting scores. The maximum storage time in ice was determined with Quantitative Descriptive Analysis (QDA) of the salmon after cooking and found to be 20-21 days. This was used as a reference to enable...... prediction of the remaining storage time of raw salmon in ice with QIM. The calculated QI evolved linearly with storage time in ice (QI=0.82x (days in ice)+0.18, R-2=0.97). Individual salmon varied in QI within each storage day. However, the multivariate analysis (PLS1) demonstrated that storage time could...

  20. 48 CFR 14.503-1 - Step one.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Step one. 14.503-1 Section... AND CONTRACT TYPES SEALED BIDDING Two-Step Sealed Bidding 14.503-1 Step one. (a) Requests for... use the two step method. (3) The requirements of the technical proposal. (4) The evaluation criteria...

  1. Thermodynamic approach and comparison of two-step and single step DME (dimethyl ether) syntheses with carbon dioxide utilization

    International Nuclear Information System (INIS)

    Chen, Wei-Hsin; Hsu, Chih-Liang; Wang, Xiao-Dong

    2016-01-01

    DME (Dimethyl ether) synthesis from syngas with CO_2 utilization through two-step and single step processes is analyzed thermodynamically. The influences of reaction temperature, H_2/CO molar ratio, and CO_2/CO molar ratio on CO and CO_2 conversions, DME selectivity and yield, and thermal behavior are evaluated. Particular attention is paid to the comparison of the performance of DME synthesis between the two different methods. In the two-step method, the addition of CO_2 suppresses the CO conversion during methanol synthesis. An increase in CO_2/CO ratio decreases the CO_2 conversion (negative effect), but increases the total consumption amount of CO_2 (positive effect). At a given reaction temperature with H_2/CO = 4, the maximum DME yield develops at CO_2/CO = 1. In the single step method, over 98% of CO can be converted and the DME yield can be as high as 0.52 mol (mol CO)"−"1 at CO_2/CO = 2. The comparison of the single step and two-step processes indicates that the maximum CO conversion, DME selectivity, and DME yield in the former are higher than those in the latter, whereas an opposite result in the maximum CO_2 conversion is observed. These results reveal that the single step process has lower thermodynamic limitation and is a better option for DME synthesis. From CO_2 utilization point of view, the operation with low temperature, high H_2/CO ratio, and low CO_2/CO ratio results in higher CO_2 conversion, irrespective of two-step or single step DME synthesis. - Highlights: • DME (Dimethyl ether) synthesis with CO_2 utilization is analyzed thermodynamically. • Single step and two-step DME syntheses are studied and compared with each other. • CO_2 addition suppresses CO conversion in MeOH synthesis but increases MeOH yield. • The performance of the single step DME synthesis is better than that of the two-step one. • Increase CO_2/CO ratio decreases CO_2 conversion but increases CO_2 consumption amount.

  2. Computation of mode eigenfunctions in graded-index optical fibers by the propagating beam method

    International Nuclear Information System (INIS)

    Feit, M.D.; Fleck, J.A. Jr.

    1980-01-01

    The propagating beam method utilizes discrete Fourier transforms for generating configuration-space solutions to optical waveguide problems without reference to modes. The propagating beam method can also give a complete description of the field in terms of modes by a Fourier analysis with respect to axial distance of the computed fields. Earlier work dealt with the accurate determination of mode propagation constants and group delays. In this paper the method is extended to the computation of mode eigenfunctions. The method is efficient, allowing generation of a large number of eigenfunctions from a single propagation run. Computations for parabolic-index profiles show excellent agreement between analytic and numerically generated eigenfunctions

  3. Comparison of Document Index Graph Using TextRank and HITS Weighting Method in Automatic Text Summarization

    Science.gov (United States)

    Hadyan, Fadhlil; Shaufiah; Arif Bijaksana, Moch.

    2017-01-01

    Automatic summarization is a system that can help someone to take the core information of a long text instantly. The system can help by summarizing text automatically. there’s Already many summarization systems that have been developed at this time but there are still many problems in those system. In this final task proposed summarization method using document index graph. This method utilizes the PageRank and HITS formula used to assess the web page, adapted to make an assessment of words in the sentences in a text document. The expected outcome of this final task is a system that can do summarization of a single document, by utilizing document index graph with TextRank and HITS to improve the quality of the summary results automatically.

  4. Numerical sensitivity computation for discontinuous gradient-only optimization problems using the complex-step method

    CSIR Research Space (South Africa)

    Wilke, DN

    2012-07-01

    Full Text Available problems that utilise remeshing (i.e. the mesh topology is allowed to change) between design updates. Here, changes in mesh topology result in abrupt changes in the discretization error of the computed response. These abrupt changes in turn manifests... in shape optimization but may be present whenever (partial) differential equations are ap- proximated numerically with non-constant discretization methods e.g. remeshing of spatial domains or automatic time stepping in temporal domains. Keywords: Complex...

  5. One-step fabrication of multifunctional micromotors

    Science.gov (United States)

    Gao, Wenlong; Liu, Mei; Liu, Limei; Zhang, Hui; Dong, Bin; Li, Christopher Y.

    2015-08-01

    Although artificial micromotors have undergone tremendous progress in recent years, their fabrication normally requires complex steps or expensive equipment. In this paper, we report a facile one-step method based on an emulsion solvent evaporation process to fabricate multifunctional micromotors. By simultaneously incorporating various components into an oil-in-water droplet, upon emulsification and solidification, a sphere-shaped, asymmetric, and multifunctional micromotor is formed. Some of the attractive functions of this model micromotor include autonomous movement in high ionic strength solution, remote control, enzymatic disassembly and sustained release. This one-step, versatile fabrication method can be easily scaled up and therefore may have great potential in mass production of multifunctional micromotors for a wide range of practical applications.Although artificial micromotors have undergone tremendous progress in recent years, their fabrication normally requires complex steps or expensive equipment. In this paper, we report a facile one-step method based on an emulsion solvent evaporation process to fabricate multifunctional micromotors. By simultaneously incorporating various components into an oil-in-water droplet, upon emulsification and solidification, a sphere-shaped, asymmetric, and multifunctional micromotor is formed. Some of the attractive functions of this model micromotor include autonomous movement in high ionic strength solution, remote control, enzymatic disassembly and sustained release. This one-step, versatile fabrication method can be easily scaled up and therefore may have great potential in mass production of multifunctional micromotors for a wide range of practical applications. Electronic supplementary information (ESI) available: Videos S1-S4 and Fig. S1-S3. See DOI: 10.1039/c5nr03574k

  6. “One Step and Two Steps” freezing methods of dog’s semen in coconut water and ethylene glycol extender Métodos de congelamento "One Step" e "Two Steps" do sêmen de cães, diluído em solução de água de coco e etilenoglicol

    Directory of Open Access Journals (Sweden)

    Marco Antonio da Rocha Ferreira

    2009-06-01

    Full Text Available The objective of this study was to verify the influence of One Step and Two Steps freezing methods on dog’s spermatic viability. The experiment was performed using 20 ejaculates from 11 previously selected dogs which presented progressive motility over 70% and vigor equal or superior to 3. The samples were frozen in medium composed by coconut water and ethylene glycol as crioprotectant by the methods, One and Two Steps. After thawing, progressive motility, vigor, live spermatozoa percentage and plasmatic membrane integrity were evaluated. The results showed that there was no difference (P>0.05 in evaluated seminal characteristics. For progressive motility, the results (mean ± standard deviation were respectively for One and Two Steps, 47.3% ± 16.6% and 50.5% ±1 7.4%. As well as, the results for vigor, live spermatozoa percentage, plasmatic membrane integrity were 2.64 ± 0.67 and 2.9 ± 0.74; 52.2% ± 24.16 and 52.2% ± 24.48%; 15.27% ± 10.19% and 23.3% ± 11.6% for One and Two Steps methods, respectively. In conclusion, the One Step and Two Steps techniques can be used as semen cryopreservation methods in dog’s assisted reproduction and there is no difference between the evaluated characteristics of frozen-thawed semen using one or other technique.Objetivou-se, com este estudo, verificar a influência dos métodos de congelamento, One Step e Two Steps, na viabilidade espermática em cães. Foram utilizados 20 ejaculados de 11 cães, previamente selecionados, que apresentaram motilidade progressiva acima de 70% e vigor igual ou superior a três. As amostras foram congeladas em meio composto de água de coco e etilenoglicol, pelos métodos de One e Two Steps, e avaliadas após descongelamento, quanto à motilidade progressiva, vigor, porcentagem de espermatozóides vivos e integridade de membrana plasmática. Após o processo de diluição e congelamento One Step e Two Steps, verificou-se que não houve diferença (P>0,05 nas caracter

  7. Simple One-Step Method to Synthesize Polypyrrole-Indigo Carmine-Silver Nanocomposite

    OpenAIRE

    Loguercio, Lara Fernandes; Demingos, Pedro; Manica, Luiza de Mattos; Griep, Jordana Borges; Santos, Marcos José Leite; Ferreira, Jacqueline

    2016-01-01

    A nanocomposite of indigo carmine doped polypyrrole/silver nanoparticles was obtained by a one-step electrochemical process. The nanocomposite was characterized by scanning electron microscopy, infrared spectroscopy, ultraviolet-visible-near infrared spectroscopy, and cyclic voltammetry. The simple one-step process allowed the growth of silver nanoparticles during the polymerization of polypyrrole, resulting in films with electrochromic behavior and improved electroactivity. In addition, poly...

  8. Tomographic method for measurement of the gradient refractive index of the crystalline lens. I. The spherical fish lens.

    Science.gov (United States)

    Acosta, Eva; Vazquez, Daniel; Garner, Leon; Smith, George

    2005-03-01

    We present an iterative tomographic algorithm to reconstruct refractive-index profiles for meridional planes of the lens of the spherical fish eye from measurements of deflection angles of refracted rays. Numerical simulations show that the algorithm allows accuracy up to the fourth decimal place, provided that the refractive index can be regarded as an analytical function of the radial coordinate and the experimental errors are neglected. An experimental demonstration is given by applying the algorithm to retrieve the refractive-index profile of a spherical fish lens. The method is conceptually simple and does not require matching of the index of the surrounding medium to that of the surface of the lens, and the related iterative algorithm rapidly converges.

  9. Risk management of stock index futures

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The Hong Kong Hang Seng index futures is taken as a study object and a method of empirical analysis is adopted in order to verify the validity of the application of the value-at-risk (VaR) method in the risk measurement of the stock index futures market. The results suggest that under normal market conditions it is feasible to apply the VaR method in the measurement of the market risks of stock index futures. The daily VaR value of the stock index futures provides a foreseeable profit and loss of the stock ...

  10. The application of the lake ecosystem index in multi-attribute decision analysis in radioecology

    International Nuclear Information System (INIS)

    Haakanson, Lars; Gallego, Eduardo; Rios-Insua, Sixto

    2000-01-01

    This work gives a summary of multi-attribute analysis (MAA) and its use in decision support systems for radiological and environmental contamination problems and presents a modification of the lake ecosystem index (LEI) as a tool to give an holistic account for the environmental (and not just radiological) consequences of chemical remedial measures (lake and wet land liming, potash treatment and lake fertilisation) carried out to reduce radionuclide levels in water, sediments and biota. The first step in determining a LEI-value is to set normal or initial values of two important limnological state variables, pH and total-P. The second step involves predicting state indices describing the abundance of key functional groups (the fish yield and biomasses of phytoplankton and bottom fauna). The next step concerns the definition of a lake ecosystem index based on the state indices. The final step is the derivation of the utility function to be used in the multi-attribute analysis to compare environmental, economical and social attributes of different dimensions (ECU, kg, Bq/kg, etc.). The ecosystem index characterises the entire lake over longer periods of time (months), and not specific sites in lakes or specific sampling events

  11. A step towards standardization: A method for end-point titer determination by fluorescence index of an automated microscope. End-point titer determination by fluorescence index.

    Science.gov (United States)

    Carbone, Teresa; Gilio, Michele; Padula, Maria Carmela; Tramontano, Giuseppina; D'Angelo, Salvatore; Pafundi, Vito

    2018-05-01

    Indirect Immunofluorescence (IIF) is widely considered the Gold Standard for Antinuclear Antibody (ANA) screening. However, the high inter-reader variability remains the major disadvantage associated with ANA testing and the main reason for the increasing demand of the computer-aided immunofluorescence microscope. Previous studies proposed the quantification of the fluorescence intensity as an alternative for the classical end-point titer evaluation. However, the different distribution of bright/dark light linked to the nature of the self-antigen and its location in the cells result in different mean fluorescence intensities. The aim of the present study was to correlate Fluorescence Index (F.I.) with end-point titers for each well-defined ANA pattern. Routine serum samples were screened for ANA testing on HEp-2000 cells using Immuno Concepts Image Navigator System, and positive samples were serially diluted to assign the end-point titer. A comparison between F.I. and end-point titers related to 10 different staining patterns was made. According to our analysis, good technical performance of F.I. (97% sensitivity and 94% specificity) was found. A significant correlation between quantitative reading of F.I. and end-point titer groups was observed using Spearman's test and regression analysis. A conversion scale of F.I. in end-point titers for each recognized ANA-pattern was obtained. The Image Navigator offers the opportunity to improve worldwide harmonization of ANA test results. In particular, digital F.I. allows quantifying ANA titers by using just one sample dilution. It could represent a valuable support for the routine laboratory and an effective tool to reduce inter- and intra-laboratory variability. Copyright © 2018. Published by Elsevier B.V.

  12. Method of and system for identification or estimation of a refractive index of a liquid

    DEFF Research Database (Denmark)

    2015-01-01

    This invention relates to a method of and a system (100) for identification or estimation of a refractive index of a liquid (120) comprising a light receiving part (111) adapted to receive polarised or non-polarised light (125; 135), a light emitting part (112) adapted, during use, to transmit...... light (130), an optical structure (110) being adapted to receive, during use, polarised light (125) via or from the light receiving part (111), and being adapted to receive, during use, a liquid (120) having a predetermined refractive index to be identified or estimated, and a first polariser (115......); is adapted, during use, to pass the received light (135) through the optical path so that a narrow wavelength range of the transmitted light (130) is influenced by the predetermined refractive index of the received liquid (120) and that the influenced narrow wavelength range, when observed by a user and...

  13. Constructing an exposure chart: step by step (based on standard procedures)

    International Nuclear Information System (INIS)

    David, Jocelyn L; Cansino, Percedita T.; Taguibao, Angileo P.

    2000-01-01

    An exposure chart is very important in conducting radiographic inspection of materials. By using an accurate exposure chart, an inspector is able to avoid a trial and error way of determining correct time to expose a specimen, thereby producing a radiograph that has an acceptable density based on a standard. The chart gives the following information: x-ray machine model and brand, distance of the x-ray tube from the film, type and thickness of intensifying screens, film type, radiograph density, and film processing conditions. The methods of preparing an exposure chart are available in existing radiographic testing manuals. These described methods are presented in step by step procedures, covering the actual laboratory set-up, data gathering, computations, and transformation of derived data into Characteristic Curve and Exposure Chart

  14. Evaluation of a Rapid One-step Real-time PCR Method as a High-throughput Screening for Quantification of Hepatitis B Virus DNA in a Resource-limited Setting.

    Science.gov (United States)

    Rashed-Ul Islam, S M; Jahan, Munira; Tabassum, Shahina

    2015-01-01

    Virological monitoring is the best predictor for the management of chronic hepatitis B virus (HBV) infections. Consequently, it is important to use the most efficient, rapid and cost-effective testing systems for HBV DNA quantification. The present study compared the performance characteristics of a one-step HBV polymerase chain reaction (PCR) vs the two-step HBV PCR method for quantification of HBV DNA from clinical samples. A total of 100 samples consisting of 85 randomly selected samples from patients with chronic hepatitis B (CHB) and 15 samples from apparently healthy individuals were enrolled in this study. Of the 85 CHB clinical samples tested, HBV DNA was detected from 81% samples by one-step PCR method with median HBV DNA viral load (VL) of 7.50 × 10 3 lU/ml. In contrast, 72% samples were detected by the two-step PCR system with median HBV DNA of 3.71 × 10 3 lU/ml. The one-step method showed strong linear correlation with two-step PCR method (r = 0.89; p Tabassum S. Evaluation of a Rapid One-step Real-time PCR Method as a High-throughput Screening for Quantification of Hepatitis B Virus DNA in a Resource-limited Setting. Euroasian J Hepato-Gastroenterol 2015;5(1):11-15.

  15. Comparison of Yamax pedometer and GT3X accelerometer steps in a free-living sample

    Science.gov (United States)

    Our objective was to compare steps detected by the Yamax pedometer (PEDO) versus the GT3X accelerometer (ACCEL) in free-living adults. Daily PEDO and ACCEL steps were collected from a sample of 23 overweight and obese participants (18 females; mean +/- sd: age = 52.6 +/- 8.4 yr.; body mass index = 3...

  16. Experimental comparison between speech transmission index, rapid speech transmission index, and speech intelligibility index.

    Science.gov (United States)

    Larm, Petra; Hongisto, Valtteri

    2006-02-01

    During the acoustical design of, e.g., auditoria or open-plan offices, it is important to know how speech can be perceived in various parts of the room. Different objective methods have been developed to measure and predict speech intelligibility, and these have been extensively used in various spaces. In this study, two such methods were compared, the speech transmission index (STI) and the speech intelligibility index (SII). Also the simplification of the STI, the room acoustics speech transmission index (RASTI), was considered. These quantities are all based on determining an apparent speech-to-noise ratio on selected frequency bands and summing them using a specific weighting. For comparison, some data were needed on the possible differences of these methods resulting from the calculation scheme and also measuring equipment. Their prediction accuracy was also of interest. Measurements were made in a laboratory having adjustable noise level and absorption, and in a real auditorium. It was found that the measurement equipment, especially the selection of the loudspeaker, can greatly affect the accuracy of the results. The prediction accuracy of the RASTI was found acceptable, if the input values for the prediction are accurately known, even though the studied space was not ideally diffuse.

  17. A new tool for the evaluation of the analytical procedure: Green Analytical Procedure Index.

    Science.gov (United States)

    Płotka-Wasylka, J

    2018-05-01

    A new means for assessing analytical protocols relating to green analytical chemistry attributes has been developed. The new tool, called GAPI (Green Analytical Procedure Index), evaluates the green character of an entire analytical methodology, from sample collection to final determination, and was created using such tools as the National Environmental Methods Index (NEMI) or Analytical Eco-Scale to provide not only general but also qualitative information. In GAPI, a specific symbol with five pentagrams can be used to evaluate and quantify the environmental impact involved in each step of an analytical methodology, mainly from green through yellow to red depicting low, medium to high impact, respectively. The proposed tool was used to evaluate analytical procedures applied in the determination of biogenic amines in wine samples, and polycyclic aromatic hydrocarbon determination by EPA methods. GAPI tool not only provides an immediately perceptible perspective to the user/reader but also offers exhaustive information on evaluated procedures. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. A Soil Service Index: a method for quantifying the value, vulnerability, and status of soil resources

    Science.gov (United States)

    Harden, J. W.; Loisel, J.; Hugelius, G.; Sulman, B. N.; Bond-Lamberty, B. P.; Abramoff, R. Z.; Malhotra, A.; Gill, A. L.

    2017-12-01

    Soils support ecological and human systems by providing a physical and biogeochemical basis for plant growth, ecological functions, water quality, and water storage, and by providing services and functions needed for economic development, human well-being, and conservation of natural resources. Quantitative evaluation of soil services, however, is inconsistent and poorly communicated, in part because we lack a scientific, unified basis for evaluating soils and their potential for serving our needs. We introduce an index of soil service (SSI) in which multiple services are numerically or quantitatively assessed, normalized to a unit-less scale for purposes of intercomparability, and evaluated for a given site or region. Services include organic matter and/or organic carbon storage; plant productivity; CO2 or GHG exchange with the atmosphere; water storage capacity; and nutrient storage and/or availability. The status of SSI can be evaluated by individual services or by a composite index that combines multiple services. The status can be monitored over time; and key services that are more highly valued for a given soil can be weighted accordingly in comparison to other services. As a first step, existing data for each service are captured from a literature and data review in order to establish the full range of values. A site value establishes the ranking relative to the full range. Key services are weighted according to local values. A final index is the sum of the normalized, weighted products. Metrics can be updated and adapted as new data or services are discovered or recognized. Metrics can be used to compare among sites, regions, or time periods.

  19. Entropy correlation distance method. The Euro introduction effect on the Consumer Price Index

    Science.gov (United States)

    Miśkiewicz, Janusz

    2010-04-01

    The idea of entropy was introduced in thermodynamics, but it can be used in time series analysis. There are various ways to define and measure the entropy of a system. Here the so called Theil index, which is often used in economy and finance, is applied as it were an entropy measure. In this study the time series are remapped through the Theil index. Then the linear correlation coefficient between the remapped time series is evaluated as a function of time and time window size and the corresponding statistical distance is defined. The results are compared with the the usual correlation distance measure for the time series themselves. As an example this entropy correlation distance method (ECDM) is applied to several series, as those of the Consumer Price Index (CPI) in order to test some so called globalisation processes. Distance matrices are calculated in order to construct two network structures which are next analysed. The role of two different time scales introduced by the Theil index and a correlation coefficient is also discussed. The evolution of the mean distance between the most developed countries is presented and the globalisation periods of the prices discussed. It is finally shown that the evolution of mean distance between the most developed countries on several networks follows the process of introducing the European currency - the Euro. It is contrasted to the GDP based analysis. It is stressed that the entropy correlation distance measure is more suitable in detecting significant changes, like a globalisation process than the usual statistical (correlation based) measure.

  20. Reliability Evaluation of Bridges Based on Nonprobabilistic Response Surface Limit Method

    Directory of Open Access Journals (Sweden)

    Xuyong Chen

    2017-01-01

    Full Text Available Due to many uncertainties in nonprobabilistic reliability assessment of bridges, the limit state function is generally unknown. The traditional nonprobabilistic response surface method is a lengthy and oscillating iteration process and leads to difficultly solving the nonprobabilistic reliability index. This article proposes a nonprobabilistic response surface limit method based on the interval model. The intention of this method is to solve the upper and lower limits of the nonprobabilistic reliability index and to narrow the range of the nonprobabilistic reliability index. If the range of the reliability index reduces to an acceptable accuracy, the solution will be considered convergent, and the nonprobabilistic reliability index will be obtained. The case study indicates that using the proposed method can avoid oscillating iteration process, make iteration process stable and convergent, reduce iteration steps significantly, and improve computational efficiency and precision significantly compared with the traditional nonprobabilistic response surface method. Finally, the nonprobabilistic reliability evaluation process of bridge will be built through evaluating the reliability of one PC continuous rigid frame bridge with three spans using the proposed method, which appears to be more simple and reliable when lack of samples and parameters in the bridge nonprobabilistic reliability evaluation is present.

  1. Phase-step retrieval for tunable phase-shifting algorithms

    Science.gov (United States)

    Ayubi, Gastón A.; Duarte, Ignacio; Perciante, César D.; Flores, Jorge L.; Ferrari, José A.

    2017-12-01

    Phase-shifting (PS) is a well-known technique for phase retrieval in interferometry, with applications in deflectometry and 3D-profiling, which requires a series of intensity measurements with certain phase-steps. Usually the phase-steps are evenly spaced, and its knowledge is crucial for the phase retrieval. In this work we present a method to extract the phase-step between consecutive interferograms. We test the proposed technique with images corrupted by additive noise. The results were compared with other known methods. We also present experimental results showing the performance of the method when spatial filters are applied to the interferograms and the effect that they have on their relative phase-steps.

  2. New 'one-step' method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels

    International Nuclear Information System (INIS)

    Ladner, Yoann; Cretier, Gerard; Dugas, Vincent; Randon, Jerome; Faure, Karine; Bruchet, Anthony

    2012-01-01

    A new method for monolith synthesis and anchoring inside cyclic olefin copolymer (COC) microchannels in a single step is proposed. It is shown that type I photo-initiators, typically used in a polymerization mixture to generate free radicals during monolith synthesis, can simultaneously act as type II photo-initiators and react with the plastic surface through hydrogen abstraction. This mechanism is used to 'photo-graft' poly(ethylene glycol) methacrylate (PEGMA) on COC surfaces. Contact angle measurements were used to observe the changes in surface hydrophilicity when increasing initiator concentration and irradiation duration. The ability of type I photo-initiators to synthesize and anchor a monolith inside COC microchannels in a single step was proved through SEM observations. Different concentrations of photo-initiators were tried. Finally, electro-chromatographic separations of polycyclic aromatic hydrocarbons were realized to illustrate the beneficial effect of anchoring on chromatographic performances. The versatility of the method was demonstrated with two widely used photo-initiators: benzoin methyl ether (BME) and azobisisobutyronitrile (AIBN). (authors)

  3. The long-run dynamic relationship between exchange rate and its attention index: Based on DCCA and TOP method

    Science.gov (United States)

    Wang, Xuan; Guo, Kun; Lu, Xiaolin

    2016-07-01

    The behavior information of financial market plays a more and more important role in modern economic system. The behavior information reflected in INTERNET search data has already been used in short-term prediction for exchange rate, stock market return, house price and so on. However, the long-run relationship between behavior information and financial market fluctuation has not been studied systematically. Further, most traditional statistic methods and econometric models could not catch the dynamic and non-linear relationship. An attention index of CNY/USD exchange rate is constructed based on search data from 360 search engine of China in this paper. Then the DCCA and Thermal Optimal Path methods are used to explore the long-run dynamic relationship between CNY/USD exchange rate and the corresponding attention index. The results show that the significant interdependency exists and the change of exchange rate is 1-2 days lag behind the attention index.

  4. Canadian children's and youth's pedometer-determined steps/day, parent-reported TV watching time, and overweight/obesity: The CANPLAY Surveillance Study

    OpenAIRE

    Tudor-Locke, Catrine; Craig, Cora L; Cameron, Christine; Griffiths, Joseph M

    2011-01-01

    Abstract Background This study examines associations between pedometer-determined steps/day and parent-reported child's Body Mass Index (BMI) and time typically spent watching television between school and dinner. Methods Young people (aged 5-19 years) were recruited through their parents by random digit dialling and mailed a data collection package. Information on height and weight and time spent watching television between school and dinner on a typical school day was collected from parents...

  5. Evolving Stochastic Learning Algorithm based on Tsallis entropic index

    Science.gov (United States)

    Anastasiadis, A. D.; Magoulas, G. D.

    2006-03-01

    In this paper, inspired from our previous algorithm, which was based on the theory of Tsallis statistical mechanics, we develop a new evolving stochastic learning algorithm for neural networks. The new algorithm combines deterministic and stochastic search steps by employing a different adaptive stepsize for each network weight, and applies a form of noise that is characterized by the nonextensive entropic index q, regulated by a weight decay term. The behavior of the learning algorithm can be made more stochastic or deterministic depending on the trade off between the temperature T and the q values. This is achieved by introducing a formula that defines a time-dependent relationship between these two important learning parameters. Our experimental study verifies that there are indeed improvements in the convergence speed of this new evolving stochastic learning algorithm, which makes learning faster than using the original Hybrid Learning Scheme (HLS). In addition, experiments are conducted to explore the influence of the entropic index q and temperature T on the convergence speed and stability of the proposed method.

  6. Fabrication of titanium removable dental prosthesis frameworks with a 2-step investment coating method.

    Science.gov (United States)

    Koike, Mari; Hummel, Susan K; Ball, John D; Okabe, Toru

    2012-06-01

    Although pure titanium is known to have good biocompatibility, a titanium alloy with better strength is needed for fabricating clinically acceptable, partial removable dental prosthesis (RDP) frameworks. The mechanical properties of an experimental Ti-5Al-5Cu alloy cast with a 2-step investment technique were examined for RDP framework applications. Patterns for tests for various properties and denture frameworks for a preliminary trial casting were invested with a 2-step coating method using 2 types of mold materials: a less reactive spinel compound (Al(2)O(3)·MgO) and a less expensive SiO(2)-based material. The yield and tensile strength (n=5), modulus of elasticity (n=5), elongation (n=5), and hardness (n=8) of the cast Ti-5Al-5Cu alloy were determined. The external appearance and internal porosities of the preliminary trial castings of denture frameworks (n=2) were examined with a conventional dental radiographic unit. Cast Ti-6Al-4V alloy and commercially pure titanium (CP Ti) were used as controls. The data for the mechanical properties were statistically analyzed with 1-way ANOVA (α=.05). The yield strength of the cast Ti-5Al-5Cu alloy was 851 MPa and the hardness was 356 HV. These properties were comparable to those of the cast Ti-6Al-4V and were higher than those of CP Ti (PAl-5Cu frameworks was found to have been incompletely cast. The cast biocompatible experimental Ti-5Al-5Cu alloy exhibited high strength when cast with a 2-step coating method. With a dedicated study to determine the effect of sprue design on the quality of castings, biocompatible Ti-5Al-5Cu RDP frameworks for a clinical trial can be produced. Copyright © 2012 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

  7. Using the geometric mean fluorescence intensity index method to measure ZAP-70 expression in patients with chronic lymphocytic leukemia

    Directory of Open Access Journals (Sweden)

    Wu YJ

    2016-02-01

    Full Text Available Yu-Jie Wu, Hui Wang, Jian-Hua Liang, Yi Miao, Lu Liu, Hai-Rong Qiu, Chun Qiao, Rong Wang, Jian-Yong Li Department of Hematology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, People’s Republic of China Abstract: Expression of ζ-chain-associated protein kinase 70 kDa (ZAP-70 in chronic lymphocytic leukemia (CLL is associated with more aggressive disease and can help differentiate CLL from cases expressing mutated or unmutated immunoglobulin heavy chain variable region (IgHV genes. However, standardizing ZAP-70 expression by flow cytometric analysis has proved unsatisfactory. The key point is that ZAP-70 is weakly expressed with a continuous expression pattern rather than a clear discrimination between positive and negative CLL cells, which means that the resulting judgment is subjective. Thus, in this study, we aimed at assessing the reliability and repeatability of ZAP-70 expression using the geometric mean fluorescence intensity (geo MFI index method based on flow cytometry with 256-channel resolution in a series of 402 CLL patients and to compare ZAP-70 with other biological and clinical prognosticators. According to IgHV mutational status, we were able to confirm that the optimal cut-off point for the geo MFI index was 3.5 in the test set. In multivariate analyses that included the major clinical and biological prognostic markers for CLL, the prognostic impact of ZAP-70 expression appeared to have stronger discriminatory power when the geo MFI index method was applied. In addition, we found that ZAP-70-positive patients according to the geo MFI index method had shorter time to first treatment or overall survival (P=0.0002, P=0.0491. This is the first report showing that ZAP-70 expression can be evaluated by a new approach, the geo MFI index, which could be a useful prognostic method as it is more reliable, less subjective, and therefore better associated with improvement of CLL prognostication

  8. Step out - Step in Sequencing Games

    NARCIS (Netherlands)

    Musegaas, M.; Borm, P.E.M.; Quant, M.

    2014-01-01

    In this paper a new class of relaxed sequencing games is introduced: the class of Step out - Step in sequencing games. In this relaxation any player within a coalition is allowed to step out from his position in the processing order and to step in at any position later in the processing order.

  9. Effect of surface plasmon polaritons on the sensitivity of refractive index measurement using total internal reflection method

    International Nuclear Information System (INIS)

    Roshan Entezar, S.

    2015-01-01

    The phase difference between two p-polarized and s-polarized plane waves which are reflected under total internal reflection from the base of a prism with a thin metal coating is studied. Typically such a quantity can be used to measure the refractive index of a test material using the total internal reflection method. It is shown that due to the excitation of surface plasmon polaritons at the interface between the tested dielectric material and the thin metal layer, the p-polarized light experiences a large phase shift which enlarges the phase difference between the p-polarized and the s-polarized waves. As a result, the sensitivity of refractive index measurement increases and the error in determining the refractive index decreases. - Highlights: • Phase difference of totally internally reflected p and s polarized beams is studied. • Excitation of the surface wave increases the phase shift of the p-polarized light. • The sensitivity of refractive index measurement increases by using a coated prism. • The error in determining the refractive index decreases using the coated prism

  10. Environmental quality evaluation for towns in Bogota; An approach to the construction of indexes of environmental quality

    International Nuclear Information System (INIS)

    Escobar, Luis; Bermudez, Tatiana

    2004-01-01

    This paper is a conceptual and methodological estimate for the construction of a synthetic indicator that allows one to come a step closer to the diagnosis of the environmental conditions of the nineteen administrative units of Bogota known as localidades. Here the contained information is synthesized in eight simple selected indicators, the index is constructed by applying analysis of principal components, of which the alignment of the localidades is derived in accordance with the value that it takes in the environmental quality index. Once the method of calculation is applied, the results indicate that the conditions of environmental quality if Bogota are not homogeneous, clearly existing environmental differences between localidades in the north and south. Also prioritization and analysis index of environmental qualities per localidades introduced, of which the principal determinants of the index of each localidad are introduced, thus providing the decision makers with important input, in order to define the base line as a stating point of the urban environmental management

  11. Is neighbourhood obesogenicity associated with body mass index in women? Application of an obesogenicity index in socioeconomically disadvantaged neighbourhoods.

    Science.gov (United States)

    Tseng, Marilyn; Thornton, Lukar E; Lamb, Karen E; Ball, Kylie; Crawford, David

    2014-11-01

    An aggregate index is potentially useful to represent neighbourhood obesogenicity. We created a conceptually-based obesogenicity index and examined its association with body mass index (BMI) among 3786 women (age 18-45y) in socio-economically disadvantaged neighbourhoods in Victoria, Australia. The index included 3 items from each of 3 domains: food resources (supermarkets, green grocers, fast food restaurants), recreational activity resources (gyms, pools, park space), and walkability (4+ leg intersections, neighbourhood walking environment, neighbourhood safety), with a possible range from 0 to 18 reflecting 0-2 for each of the 9 items. Using generalised estimating equations, neighbourhood obesogenicity was not associated with BMI in the overall sample. However, stratified analyses revealed generally positive associations with BMI in urban areas and inverse associations in rural areas (interaction p=0.02). These analyses are a first step towards combining neighbourhood characteristics into an aggregate obesogenicity index that is transparent enough to be adopted elsewhere and to allow examination of the relevance of its specific components in different settings. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Rapid, single-step most-probable-number method for enumerating fecal coliforms in effluents from sewage treatment plants

    Science.gov (United States)

    Munoz, E. F.; Silverman, M. P.

    1979-01-01

    A single-step most-probable-number method for determining the number of fecal coliform bacteria present in sewage treatment plant effluents is discussed. A single growth medium based on that of Reasoner et al. (1976) and consisting of 5.0 gr. proteose peptone, 3.0 gr. yeast extract, 10.0 gr. lactose, 7.5 gr. NaCl, 0.2 gr. sodium lauryl sulfate, and 0.1 gr. sodium desoxycholate per liter is used. The pH is adjusted to 6.5, and samples are incubated at 44.5 deg C. Bacterial growth is detected either by measuring the increase with time in the electrical impedance ratio between the innoculated sample vial and an uninnoculated reference vial or by visual examination for turbidity. Results obtained by the single-step method for chlorinated and unchlorinated effluent samples are in excellent agreement with those obtained by the standard method. It is suggested that in automated treatment plants impedance ratio data could be automatically matched by computer programs with the appropriate dilution factors and most probable number tables already in the computer memory, with the corresponding result displayed as fecal coliforms per 100 ml of effluent.

  13. Step out-step in sequencing games

    NARCIS (Netherlands)

    Musegaas, Marieke; Borm, Peter; Quant, Marieke

    2015-01-01

    In this paper a new class of relaxed sequencing games is introduced: the class of Step out–Step in sequencing games. In this relaxation any player within a coalition is allowed to step out from his position in the processing order and to step in at any position later in the processing order. First,

  14. Steps That Count: Physical Activity Recommendations, Brisk Walking, and Steps Per Minute-How Do They Relate?

    NARCIS (Netherlands)

    Pillay, J.; Kolbe-Alexander, T.L.; Proper, K.I.; van Mechelen, W.; Lambert, E.V.

    2014-01-01

    Background: Brisk walking is recommended as a form of health-enhancing physical activity. This study determines the steps/minute rate corresponding to self-paced brisk walking (SPBW); a predicted steps/minute rate for moderate physical activity (MPA) and a comparison of the 2 findings. Methods: A

  15. Critical flux determination by flux-stepping

    DEFF Research Database (Denmark)

    Beier, Søren; Jonsson, Gunnar Eigil

    2010-01-01

    In membrane filtration related scientific literature, often step-by-step determined critical fluxes are reported. Using a dynamic microfiltration device, it is shown that critical fluxes determined from two different flux-stepping methods are dependent upon operational parameters such as step...... length, step height, and.flux start level. Filtrating 8 kg/m(3) yeast cell suspensions by a vibrating 0.45 x 10(-6) m pore size microfiltration hollow fiber module, critical fluxes from 5.6 x 10(-6) to 1.2 x 10(-5) m/s have been measured using various step lengths from 300 to 1200 seconds. Thus......, such values are more or less useless in itself as critical flux predictors, and constant flux verification experiments have to be conducted to check if the determined critical fluxes call predict sustainable flux regimes. However, it is shown that using the step-by-step predicted critical fluxes as start...

  16. Two-step Purification Method for Aging Pigments A2E and Iso-A2E Using Medium Pressure Liquid Chromatography

    International Nuclear Information System (INIS)

    Park, Sang Il; Park, Sang Cheol; Kim, So Ra; Jang, Young Pyo

    2016-01-01

    A newly modified method for the efficient purification of A2E and iso-A2E using reverse phase silica gel resin with medium pressure liquid chromatography (MPLC) was suggested. MPLC is one of the various preparative column chromatography techniques and separation under pressure renders the use of smaller particle size resins possible and increases the diversity of available stationary phases. A simplified two-step purification method was developed for the purification of aging pigments in eye, A2E and iso-A2E. With simple two-step elution of mobile phase in reverse phase MPLC, A2E and iso-A2E were successfully purified with great efficiency compare with previous column chromatography and HPLC method. This method provides more simple, convenient, cost-effective, and less time-consuming procedure for mass purification of aging pigments A2E and iso-A2E

  17. Two-step Purification Method for Aging Pigments A2E and Iso-A2E Using Medium Pressure Liquid Chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sang Il; Park, Sang Cheol [Kyunghee Univ., Seoul (Korea, Republic of); Kim, So Ra; Jang, Young Pyo [Seoul National Univ., Seoul (Korea, Republic of)

    2016-09-15

    A newly modified method for the efficient purification of A2E and iso-A2E using reverse phase silica gel resin with medium pressure liquid chromatography (MPLC) was suggested. MPLC is one of the various preparative column chromatography techniques and separation under pressure renders the use of smaller particle size resins possible and increases the diversity of available stationary phases. A simplified two-step purification method was developed for the purification of aging pigments in eye, A2E and iso-A2E. With simple two-step elution of mobile phase in reverse phase MPLC, A2E and iso-A2E were successfully purified with great efficiency compare with previous column chromatography and HPLC method. This method provides more simple, convenient, cost-effective, and less time-consuming procedure for mass purification of aging pigments A2E and iso-A2E.

  18. Using the geometric mean fluorescence intensity index method to measure ZAP-70 expression in patients with chronic lymphocytic leukemia.

    Science.gov (United States)

    Wu, Yu-Jie; Wang, Hui; Liang, Jian-Hua; Miao, Yi; Liu, Lu; Qiu, Hai-Rong; Qiao, Chun; Wang, Rong; Li, Jian-Yong

    2016-01-01

    Expression of ζ-chain-associated protein kinase 70 kDa (ZAP-70) in chronic lymphocytic leukemia (CLL) is associated with more aggressive disease and can help differentiate CLL from cases expressing mutated or unmutated immunoglobulin heavy chain variable region (IgHV) genes. However, standardizing ZAP-70 expression by flow cytometric analysis has proved unsatisfactory. The key point is that ZAP-70 is weakly expressed with a continuous expression pattern rather than a clear discrimination between positive and negative CLL cells, which means that the resulting judgment is subjective. Thus, in this study, we aimed at assessing the reliability and repeatability of ZAP-70 expression using the geometric mean fluorescence intensity (geo MFI) index method based on flow cytometry with 256-channel resolution in a series of 402 CLL patients and to compare ZAP-70 with other biological and clinical prognosticators. According to IgHV mutational status, we were able to confirm that the optimal cut-off point for the geo MFI index was 3.5 in the test set. In multivariate analyses that included the major clinical and biological prognostic markers for CLL, the prognostic impact of ZAP-70 expression appeared to have stronger discriminatory power when the geo MFI index method was applied. In addition, we found that ZAP-70-positive patients according to the geo MFI index method had shorter time to first treatment or overall survival (P=0.0002, P=0.0491). This is the first report showing that ZAP-70 expression can be evaluated by a new approach, the geo MFI index, which could be a useful prognostic method as it is more reliable, less subjective, and therefore better associated with improvement of CLL prognostication and prediction of clinical course.

  19. Tree-based indexing for real-time ConvNet landmark-based visual place recognition

    Directory of Open Access Journals (Sweden)

    Yi Hou

    2017-01-01

    Full Text Available Recent impressive studies on using ConvNet landmarks for visual place recognition take an approach that involves three steps: (a detection of landmarks, (b description of the landmarks by ConvNet features using a convolutional neural network, and (c matching of the landmarks in the current view with those in the database views. Such an approach has been shown to achieve the state-of-the-art accuracy even under significant viewpoint and environmental changes. However, the computational burden in step (c significantly prevents this approach from being applied in practice, due to the complexity of linear search in high-dimensional space of the ConvNet features. In this article, we propose two simple and efficient search methods to tackle this issue. Both methods are built upon tree-based indexing. Given a set of ConvNet features of a query image, the first method directly searches the features’ approximate nearest neighbors in a tree structure that is constructed from ConvNet features of database images. The database images are voted on by features in the query image, according to a lookup table which maps each ConvNet feature to its corresponding database image. The database image with the highest vote is considered the solution. Our second method uses a coarse-to-fine procedure: the coarse step uses the first method to coarsely find the top-N database images, and the fine step performs a linear search in Hamming space of the hash codes of the ConvNet features to determine the best match. Experimental results demonstrate that our methods achieve real-time search performance on five data sets with different sizes and various conditions. Most notably, by achieving an average search time of 0.035 seconds/query, our second method improves the matching efficiency by the three orders of magnitude over a linear search baseline on a database with 20,688 images, with negligible loss in place recognition accuracy.

  20. Time step size selection for radiation diffusion calculations

    International Nuclear Information System (INIS)

    Rider, W.J.; Knoll, D.A.

    1999-01-01

    The purpose of this note is to describe a time step control technique as applied to radiation diffusion. Standard practice only provides a heuristic criteria related to the relative change in the dependent variables. The authors propose an alternative based on relatively simple physical principles. This time step control applies to methods of solution that are unconditionally stable and converges nonlinearities within a time step in the governing equations. Commonly, nonlinearities in the governing equations are evaluated using existing (old time) data. The authors refer to this as the semi-implicit (SI) method. When a method converges nonlinearities within a time step, the entire governing equation including all nonlinearities is self-consistently evaluated using advance time data (with appropriate time centering for accuracy)

  1. Calculation of beam paths in optical systems containing inhomogeneous isotropic media with cylindrical distribution of the refractive index

    International Nuclear Information System (INIS)

    Grammatin, A.P.; Degen, A.B.; Katranova, N.A.

    1995-01-01

    A system of differential equations convenient for numerical computer integrating is proposed to calculate beam paths, elementary astigmatic beams, and the optical path in isotropic media with cylindrical distribution of the refractive index. A method for selecting the step of this integration is proposed. This technique is implemented in the program package for computers of the VAX series meant for the computer-aided design of optical systems. 4 refs

  2. The clinical features of alcohol use disorders in biological and step-fathers that predict risk for alcohol use disorders in offspring.

    Science.gov (United States)

    Kendler, Kenneth S; Ohlsson, Henrik; Edwards, Alexis; Sundquist, Jan; Sundquist, Kristina

    2017-12-01

    Given that Alcohol Use Disorder (AUD) is clinically heterogeneous, can we, in a large epidemiological sample using public registries, identify clinical features of AUD cases in biological and step-fathers that index, respectively, genetic and familial-environmental risk for AUD in their offspring? From all father-offspring pairs where the father had AUD and the offspring was born 1960-1990, we identified not-lived-with (NLW) biological fathers (n = 38,376) and step-father pairs (n = 9,711). The relationship between clinical and historical features of the father's AUD and risk for AUD in offspring was assessed by linear hazard regression. Age at first registration for AUD and recurrence of AUD registration were significantly stronger predictors of risk for AUD in the offspring of NLW fathers than in step-fathers. By contrast, number of AUD registrations in NLW fathers and step-fathers were equally predictive of risk for AUD in offspring. However, while the number of step-father AUD registrations that occurred when he was living them with significantly predicted risk for AUD in his step-children, the number of registrations that occurred when not residing with his step-children was unassociated with their AUD risk. In an epidemiological sample, we could meaningfully differentiate between features of AUD in fathers that indexed genetic risk which was transmitted to biological offspring (early age at onset and recurrence) versus indexed environmental risk (registrations while rearing) which increased risk in step-children. © 2017 Wiley Periodicals, Inc.

  3. Application of the thermal step method to space charge measurements in inhomogeneous solid insulating structures: A theoretical approach

    International Nuclear Information System (INIS)

    Cernomorcenco, Andrei; Notingher, Petru Jr.

    2008-01-01

    The thermal step method is a nondestructive technique for determining electric charge distribution across solid insulating structures. It consists in measuring and analyzing a transient capacitive current due to the redistribution of influence charges when the sample is crossed by a thermal wave. This work concerns the application of the technique to inhomogeneous insulating structures. A general equation of the thermal step current appearing in such a sample is established. It is shown that this expression is close to the one corresponding to a homogeneous sample and allows using similar techniques for calculating electric field and charge distribution

  4. A three-step Maximum-A-Posterior probability method for InSAR data inversion of coseismic rupture with application to four recent large earthquakes in Asia

    Science.gov (United States)

    Sun, J.; Shen, Z.; Burgmann, R.; Liang, F.

    2012-12-01

    We develop a three-step Maximum-A-Posterior probability (MAP) method for coseismic rupture inversion, which aims at maximizing the a posterior probability density function (PDF) of elastic solutions of earthquake rupture. The method originates from the Fully Bayesian Inversion (FBI) and the Mixed linear-nonlinear Bayesian inversion (MBI) methods , shares the same a posterior PDF with them and keeps most of their merits, while overcoming its convergence difficulty when large numbers of low quality data are used and improving the convergence rate greatly using optimization procedures. A highly efficient global optimization algorithm, Adaptive Simulated Annealing (ASA), is used to search for the maximum posterior probability in the first step. The non-slip parameters are determined by the global optimization method, and the slip parameters are inverted for using the least squares method without positivity constraint initially, and then damped to physically reasonable range. This step MAP inversion brings the inversion close to 'true' solution quickly and jumps over local maximum regions in high-dimensional parameter space. The second step inversion approaches the 'true' solution further with positivity constraints subsequently applied on slip parameters using the Monte Carlo Inversion (MCI) technique, with all parameters obtained from step one as the initial solution. Then the slip artifacts are eliminated from slip models in the third step MAP inversion with fault geometry parameters fixed. We first used a designed model with 45 degree dipping angle and oblique slip, and corresponding synthetic InSAR data sets to validate the efficiency and accuracy of method. We then applied the method on four recent large earthquakes in Asia, namely the 2010 Yushu, China earthquake, the 2011 Burma earthquake, the 2011 New Zealand earthquake and the 2008 Qinghai, China earthquake, and compared our results with those results from other groups. Our results show the effectiveness of

  5. Simple One-Step Method to Synthesize Polypyrrole-Indigo Carmine-Silver Nanocomposite

    Directory of Open Access Journals (Sweden)

    Lara Fernandes Loguercio

    2016-01-01

    Full Text Available A nanocomposite of indigo carmine doped polypyrrole/silver nanoparticles was obtained by a one-step electrochemical process. The nanocomposite was characterized by scanning electron microscopy, infrared spectroscopy, ultraviolet-visible-near infrared spectroscopy, and cyclic voltammetry. The simple one-step process allowed the growth of silver nanoparticles during the polymerization of polypyrrole, resulting in films with electrochromic behavior and improved electroactivity. In addition, polypyrrole chains in the nanocomposite were found to present longer conjugation length than pristine polypyrrole films.

  6. [Authorization, translation, back translation and language modification of the simplified Chinese adult comorbidity-27 index].

    Science.gov (United States)

    Gao, L; Mao, C; Yu, G Y; Peng, X

    2016-10-09

    Objective: To translate the adult comorbidity evaluation-27(ACE-27) index authored by professor JF Piccirillo into Chinese and for the purpose of assessing the possible impact of comorbidity on survival of oral cancer patients and improving cancer staging. Methods: The translation included the following steps, obtaining permission from professor Piccirillo, translation, back translation, language modification, adjusted by the advice from the professors of oral and maxillofacial surgery. The test population included 154 patients who were admitted to Peking University of Stomatology during March 2011. Questionnaire survey was conducted on these patients. Retest of reliability, internal consistency reliability, content validity, and structure validity were performed. Results: The simplified Chinese ACE-27 index was established. The Cronbach's α was 0.821 in the internal consistency reliability test. The Kaiser-Meyer-Olkin (KMO) value of 8 items was 0.859 in the structure validity test. Conclusions: The simplified Chinese ACE-27 index has good feasibility and reliability. It is useful to assess the comorbidity of oral cancer patients.

  7. A novel single-step synthesis of N-doped TiO2 via a sonochemical method

    International Nuclear Information System (INIS)

    Wang, Xi-Kui; Wang, Chen; Guo, Wei-Lin; Wang, Jin-Gang

    2011-01-01

    Graphical abstract: The N-doped anatase TiO 2 nanoparticles were synthesized by sonochemical method. The as-prepared sample is characterized by XRD, TEM, XPS and UV-Vis DRS. The photocatalytic activity of the photocatalyst was evaluated by the photodegradation of an azo dye direct sky blue 5B. Highlights: → A novel singal-step sonochemical synthesis method for the preparation of anatase N-doped TiO 2 nanocrystalline at low temperature has been devoleped. → The as-prepared sample is characterized by XRD, TEM, XPS and UV-Vis DRS. → The photodegradation of azo dye direct sky blue 5 showed that the N-doped TiO 2 catalyst is of high visible-light photocatalytic activity. -- Abstract: A novel single-step synthetic method for the preparation of anatase N-doped TiO 2 nanocrystalline at low temperature has been devoleped. The N-doped anatase TiO 2 nanoparticles were synthesized by sonication of the solution of tetraisopropyl titanium and urea in water and isopropyl alcohol at 80 o C for 150 min. The as-prepared sample was characterized by X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy and UV-vis absorption spectrum. The product structure depends on the reaction temperature and reaction time. The photocatalytic activity of the as-prepared photocatalyst was evaluated via the photodegradation of an azo dye direct sky blue 5B. The results show that the N-doped TiO 2 nanocrystalline prepared via sonication exhibit an excellent photocatalytic activity under UV light and simulated sunlight.

  8. Effects of walking speed on the step-by-step control of step width.

    Science.gov (United States)

    Stimpson, Katy H; Heitkamp, Lauren N; Horne, Joscelyn S; Dean, Jesse C

    2018-02-08

    Young, healthy adults walking at typical preferred speeds use step-by-step adjustments of step width to appropriately redirect their center of mass motion and ensure mediolateral stability. However, it is presently unclear whether this control strategy is retained when walking at the slower speeds preferred by many clinical populations. We investigated whether the typical stabilization strategy is influenced by walking speed. Twelve young, neurologically intact participants walked on a treadmill at a range of prescribed speeds (0.2-1.2 m/s). The mediolateral stabilization strategy was quantified as the proportion of step width variance predicted by the mechanical state of the pelvis throughout a step (calculated as R 2 magnitude from a multiple linear regression). Our ability to accurately predict the upcoming step width increased over the course of a step. The strength of the relationship between step width and pelvis mechanics at the start of a step was reduced at slower speeds. However, these speed-dependent differences largely disappeared by the end of a step, other than at the slowest walking speed (0.2 m/s). These results suggest that mechanics-dependent adjustments in step width are a consistent component of healthy gait across speeds and contexts. However, slower walking speeds may ease this control by allowing mediolateral repositioning of the swing leg to occur later in a step, thus encouraging slower walking among clinical populations with limited sensorimotor control. Published by Elsevier Ltd.

  9. Linking pedestrian flow characteristics with stepping locomotion

    Science.gov (United States)

    Wang, Jiayue; Boltes, Maik; Seyfried, Armin; Zhang, Jun; Ziemer, Verena; Weng, Wenguo

    2018-06-01

    While properties of human traffic flow are described by speed, density and flow, the locomotion of pedestrian is based on steps. To relate characteristics of human locomotor system with properties of human traffic flow, this paper aims to connect gait characteristics like step length, step frequency, swaying amplitude and synchronization with speed and density and thus to build a ground for advanced pedestrian models. For this aim, observational and experimental study on the single-file movement of pedestrians at different densities is conducted. Methods to measure step length, step frequency, swaying amplitude and step synchronization are proposed by means of trajectories of the head. Mathematical models for the relations of step length or frequency and speed are evaluated. The problem how step length and step duration are influenced by factors like body height and density is investigated. It is shown that the effect of body height on step length and step duration changes with density. Furthermore, two different types of step in-phase synchronization between two successive pedestrians are observed and the influence of step synchronization on step length is examined.

  10. Chiroplasmonic magnetic gold nanocomposites produced by one-step aqueous method using κ-carrageenan.

    Science.gov (United States)

    Lesnichaya, Marina V; Sukhov, Boris G; Aleksandrova, Galina P; Gasilova, Ekaterina R; Vakul'skaya, Tamara I; Khutsishvili, Spartak S; Sapozhnikov, Anatoliy N; Klimenkov, Igor V; Trofimov, Boris A

    2017-11-01

    Novel water-soluble chiroplasmonic nanobiocomposites with directly varied gold content were synthesized by a one-step redox method in water using a biocompatible polysaccharide κ-carrageenan (industrial product from algae) as both reducing and stabilizing matrix. The influence of the reactants ratio, temperature, and pH on the reaction was studied and the optimal reaction parameters were found. The structure and the properties of composite nanomaterials were examined in solid state and aqueous solutions by using complementary physical-chemical methods X-ray diffraction analysis, transmission electron microscopy, spectroscopy of electron paramagnetic resonance, atomic absorption and optical spectroscopy, polarimetry including optical rotatory dispersion with registration of interphase-crossbred Cotton effect of a chiral polysaccharide matrix on plasmonic chromophore of gold nanoparticles, dynamic and static light scattering. The new perspective multi-purpose nanocomposites demonstrate a complex of chiroplasmonic and magnetic properties, imparted by both nanoparticles and radicals enriched chiral polysaccharide matrix. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Step-by-step optimization and global chaos of nonlinear parameters in exact calculations of few-particle systems

    International Nuclear Information System (INIS)

    Frolov, A.M.

    1986-01-01

    Exact variational calculations are treated for few-particle systems in the exponential basis of relative coordinates using nonlinear parameters. The methods of step-by-step optimization and global chaos of nonlinear parameters are applied to calculate the S and P states of ppμ, ddμ, ttμ homonuclear mesomolecules within the error ≤±0.001 eV. The global chaos method turned out to be well applicable to nuclear 3 H and 3 He systems

  12. Determination of laser cutting process conditions using the preference selection index method

    Science.gov (United States)

    Madić, Miloš; Antucheviciene, Jurgita; Radovanović, Miroslav; Petković, Dušan

    2017-03-01

    Determination of adequate parameter settings for improvement of multiple quality and productivity characteristics at the same time is of great practical importance in laser cutting. This paper discusses the application of the preference selection index (PSI) method for discrete optimization of the CO2 laser cutting of stainless steel. The main motivation for application of the PSI method is that it represents an almost unexplored multi-criteria decision making (MCDM) method, and moreover, this method does not require assessment of the considered criteria relative significances. After reviewing and comparing the existing approaches for determination of laser cutting parameter settings, the application of the PSI method was explained in detail. Experiment realization was conducted by using Taguchi's L27 orthogonal array. Roughness of the cut surface, heat affected zone (HAZ), kerf width and material removal rate (MRR) were considered as optimization criteria. The proposed methodology is found to be very useful in real manufacturing environment since it involves simple calculations which are easy to understand and implement. However, while applying the PSI method it was observed that it can not be useful in situations where there exist a large number of alternatives which have attribute values (performances) very close to those which are preferred.

  13. CORRECTION OF CHAIN-LINKING METHOD BY MEANS OF LLOYD-MOULTON-FISHER-TÖRNQVIST INDEX ON CROATIAN GDP DATA

    Directory of Open Access Journals (Sweden)

    Ante Rozga

    2013-02-01

    Full Text Available National statistical agencies of European Union use chain-linking method to achieve the best possible decomposition of GDP. The main advantage of this method is its simplicity, thus it can be applied in practice, which makes it particularly attractive in the situation when GDP has to be compiled on due time. By this method transformation-substitution effect – inherent to rational producers and consumers, has been implicitly built into GDP compilation, which is prior assumption of normative economic theory. On empirical (ex-post ground it gives more precise volume-price decomposition. In this paper, by means of constructing LMTF index and Fisher index derived from the previous one, it is suggested how to improve chain linking method, due to following reasons: a it is theoretically restrictive, b it gives only rough GDP decomposition into volume and price and, what seems to be its main disadvantage, c it gives additively inconsistent GDP.

  14. DIDA: Distributed Indexing Dispatched Alignment.

    Directory of Open Access Journals (Sweden)

    Hamid Mohamadi

    Full Text Available One essential application in bioinformatics that is affected by the high-throughput sequencing data deluge is the sequence alignment problem, where nucleotide or amino acid sequences are queried against targets to find regions of close similarity. When queries are too many and/or targets are too large, the alignment process becomes computationally challenging. This is usually addressed by preprocessing techniques, where the queries and/or targets are indexed for easy access while searching for matches. When the target is static, such as in an established reference genome, the cost of indexing is amortized by reusing the generated index. However, when the targets are non-static, such as contigs in the intermediate steps of a de novo assembly process, a new index must be computed for each run. To address such scalability problems, we present DIDA, a novel framework that distributes the indexing and alignment tasks into smaller subtasks over a cluster of compute nodes. It provides a workflow beyond the common practice of embarrassingly parallel implementations. DIDA is a cost-effective, scalable and modular framework for the sequence alignment problem in terms of memory usage and runtime. It can be employed in large-scale alignments to draft genomes and intermediate stages of de novo assembly runs. The DIDA source code, sample files and user manual are available through http://www.bcgsc.ca/platform/bioinfo/software/dida. The software is released under the British Columbia Cancer Agency License (BCCA, and is free for academic use.

  15. Proposal of an environmental performance index to assess solid waste treatment technologies.

    Science.gov (United States)

    Coelho, Hosmanny Mauro Goulart; Lange, Liséte Celina; Coelho, Lineker Max Goulart

    2012-07-01

    Although the concern with sustainable development and environment protection has considerably grown in the last years it is noted that the majority of decision making models and tools are still either excessively tied to economic aspects or geared to the production process. Moreover, existing models focus on the priority steps of solid waste management, beyond waste energy recovery and disposal. So, in order to help the lack of models and tools aiming at the waste treatment and final disposal, a new concept is proposed: the Cleaner Treatment, which is based on the Cleaner Production principles. This paper focuses on the development and validation of the Cleaner Treatment Index (CTI), to assess environmental performance of waste treatment technologies based on the Cleaner Treatment concept. The index is formed by aggregation (summation or product) of several indicators that consists in operational parameters. The weights of the indicator were established by Delphi Method and Brazilian Environmental Laws. In addition, sensitivity analyses were carried out comparing both aggregation methods. Finally, index validation was carried out by applying the CTI to 10 waste-to-energy plants data. From sensitivity analysis and validation results it is possible to infer that summation model is the most suitable aggregation method. For summation method, CTI results were superior to 0.5 (in a scale from 0 to 1) for most facilities evaluated. So, this study demonstrates that CTI is a simple and robust tool to assess and compare the environmental performance of different treatment plants being an excellent quantitative tool to support Cleaner Treatment implementation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. One-step method for the fabrication of superhydrophobic surface on magnesium alloy and its corrosion protection, antifouling performance

    International Nuclear Information System (INIS)

    Zhao, Lin; Liu, Qi; Gao, Rui; Wang, Jun; Yang, Wanlu; Liu, Lianhe

    2014-01-01

    Highlights: •The myristic acid iron superhydrophobic surface was formatted on AZ31. •Two procedures to build a super-hydrophobic were simplified to one step. •The superhydrophobic surface shows good anticorrosion, antifouling properties. •We report a new approach for the superhydrophobic surface protection on AZ31. -- Abstract: Inspired by the lotus leaf, various methods to fabricate artificial superhydrophobic surfaces have been developed. Our purpose is to create a simple, one-step and environment-friendly method to construct a superhydrophobic surface on a magnesium alloy substrate. The substrate was immersed in a solution containing ferric chloride (FeCl 3 ·6H 2 O), deionized water, tetradecanoic acid (CH 3 (CH 2 ) 12 COOH) and ethanol. Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and Fourier transformed infrared (FT-IR) were employed to characterize the substrate surface. The obtained surface showed a micron rough structure, a high contact angle (CA) of 165° ± 2° and desirable corrosion protection and antifouling properties

  17. Solution of the schrodinger equation in one dimension by simple method for a simple step potential

    International Nuclear Information System (INIS)

    Ertik, H.

    2005-01-01

    The coefficients of the transmission and reflection for the simple-step barrier potential were calculated by a simple method. Their values were entirely different from those often encountered in the literature. Especially in the case that the total energy is equal to the barrier potential, the value of 0,20 for the reflection coefficient was obtained whereas this is zero in the literature. This may be considered as an interesting point

  18. Evaluation of one-step luminescent cyanoacrylate fuming.

    Science.gov (United States)

    Khuu, Alicia; Chadwick, Scott; Spindler, Xanthe; Lam, Rolanda; Moret, Sébastien; Roux, Claude

    2016-06-01

    One-step luminescent cyanoacrylates have recently been introduced as an alternative to the conventional cyanoacrylate fuming methods. These new techniques do not require the application of a luminescent post-treatment in order to enhance cyanoacrylate-developed fingermarks. In this study, three one-step polymer cyanoacrylates: CN Yellow Crystals (Aneval Inc.), PolyCyano UV (Foster+Freeman Ltd.) and PECA Multiband (BVDA), and one monomer cyanoacrylate: Lumikit™ (Crime Scene Technology), were evaluated against a conventional two-step cyanoacrylate fuming method (Cyanobloom (Foster+Freeman Ltd.) with rhodamine 6G stain). The manufacturers' recommended conditions or conditions compatible with the MVC™ 1000/D (Foster+Freeman Ltd.) were assessed with fingermarks aged for up to 8 weeks on non-porous and semi-porous substrates. Under white light, Cyanobloom generally gave better development than the one-step treatments across the substrates. Similarly when viewed under the respective luminescent conditions, Cyanobloom with rhodamine 6G stain resulted in improved contrast against the one-step treatments except on polystyrene, where PolyCyano UV and PECA Multiband gave better visualisation. Rhodamine 6G post-treatment of one-step samples did not significantly enhance the contrast of any of the one-step treatments against Cyanobloom/rhodamine 6G-treated samples. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. Step-by-step optimization and global chaos of nonlinear parameters in exact calculations of few-particle systems

    Energy Technology Data Exchange (ETDEWEB)

    Frolov, A M

    1986-09-01

    Exact variational calculations are treated for few-particle systems in the exponential basis of relative coordinates using nonlinear parameters. The methods of step-by-step optimization and global chaos of nonlinear parameters are applied to calculate the S and P states of pp..mu.., dd..mu.., tt..mu.. homonuclear mesomolecules within the error less than or equal to+-0.001 eV. The global chaos method turned out to be well applicable to nuclear /sup 3/H and /sup 3/He systems.

  20. Step-by-step phacoemulsification training program for ophthalmology residents

    Directory of Open Access Journals (Sweden)

    Wang Yulan

    2013-01-01

    Full Text Available Aims: The aim was to analyze the learning curve of phacoemulsification (phaco performed by residents without experience in performing extra-capsular cataract extraction (ECCE in a step-by-step training program (SBSTP. Materials and Methods: Consecutive surgical records of phaco performed from March 2009 to Sept 2011 by four residents without previous ECCE experience were retrospectively reviewed. The completion rate of the first 30 procedures by each resident was calculated. The main intraoperative phaco parameter records for the first 30 surgeries by each resident were compared with those for their last 30 surgeries. Intraoperative complications in the residents′ procedures were also recorded and analyzed. Results: A total of 1013 surgeries were performed by residents. The completion rate for the first 30 phaco procedures was 79.2 μ 5.8%. The main reasons for halting the procedure were as follows: Anterior capsule tear, inability to crack the nucleus, and posterior capsular rupture during phaco or cortex removal. Cumulative dissipated energy of phaco power used during the surgeries was significantly less in the last 30 cases compared with the first 30 cases (30.10 μ 17.58 vs. 55.41 μ 37.59, P = 0.021. Posterior capsular rupture rate was 2.5 μ 1.2% in total (10.8 μ 4.2% in the first 30 cases and 1.7 μ 1.9% in the last 30 cases, P = 0.008; a statistically significant difference. Conclusion:The step-by-step training program might be a necessary process for a resident to transit from dependence to a self-supported operator. It is also an essential middle step between wet lab training to performing the entire phaco procedure on the patient both effectively and safely.

  1. Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification

    Science.gov (United States)

    Zelber-Sagi, Shira; Webb, Muriel; Assy, Nimer; Blendis, Laurie; Yeshua, Hanny; Leshno, Moshe; Ratziu, Vlad; Halpern, Zamir; Oren, Ran; Santo, Erwin

    2013-01-01

    AIM: To compare noninvasive methods presently used for steatosis detection and quantification in nonalcoholic fatty liver disease (NAFLD). METHODS: Cross-sectional study of subjects from the general population, a subgroup from the First Israeli National Health Survey, without excessive alcohol consumption or viral hepatitis. All subjects underwent anthropometric measurements and fasting blood tests. Evaluation of liver fat was performed using four noninvasive methods: the SteatoTest; the fatty liver index (FLI); regular abdominal ultrasound (AUS); and the hepatorenal ultrasound index (HRI). Two of the noninvasive methods have been validated vs liver biopsy and were considered as the reference methods: the HRI, the ratio between the median brightness level of the liver and right kidney cortex; and the SteatoTest, a biochemical surrogate marker of liver steatosis. The FLI is calculated by an algorithm based on triglycerides, body mass index, γ-glutamyl-transpeptidase and waist circumference, that has been validated only vs AUS. FLI fatty liver. RESULTS: Three hundred and thirty-eight volunteers met the inclusion and exclusion criteria and had valid tests. The prevalence rate of NAFLD was 31.1% according to AUS. The FLI was very strongly correlated with SteatoTest (r = 0.91, P fatty liver by SteatoTest (≥ S2) and by FLI (≥ 60) was 0.74, which represented good agreement. The sensitivity of FLI vs SteatoTest was 85.5%, specificity 92.6%, positive predictive value (PPV) 74.7%, and negative predictive value (NPV) 96.1%. Most subjects (84.2%) with FLI fatty liver by HRI (≥ 1.5) and by FLI (≥ 60) was 0.43, which represented only moderate agreement. The sensitivity of FLI vs HRI was 56.3%, specificity 86.5%, PPV 57.0%, and NPV 86.1%. The diagnostic accuracy of FLI for steatosis > 5%, as predicted by SteatoTest, yielded an area under the receiver operating characteristic curve (AUROC) of 0.97 (95% CI: 0.95-0.98). The diagnostic accuracy of FLI for steatosis > 5%, as

  2. Multi-time-step domain coupling method with energy control

    DEFF Research Database (Denmark)

    Mahjoubi, N.; Krenk, Steen

    2010-01-01

    the individual time step. It is demonstrated that displacement continuity between the subdomains leads to cancelation of the interface contributions to the energy balance equation, and thus stability and algorithmic damping properties of the original algorithms are retained. The various subdomains can...... by a numerical example using a refined mesh around concentrated forces. Copyright © 2010 John Wiley & Sons, Ltd....

  3. Production and characterization of carbon nano colloid via one-step electrochemical method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Doohyun; Hwang, Yujin; Cheong, Seong Ir; Lee, Jae Keun [Pusan National University, Department of Mechanical Engineering (Korea, Republic of); Hong, Daeseung; Moon, Seongyong [N-BARO TECH CO., LTD, Institute of SamchangTsinghua Nano Application (Korea, Republic of); Lee, Jung Eun [Pusan National University, Industrial Liaison Innovation Cluster (Korea, Republic of); Kim, Soo H., E-mail: sookim@pusan.ac.k [Pusan National University, Department of Nanosystem and Nanoprocess Engineering (Korea, Republic of)

    2008-10-15

    We present a one-step electrochemical method to produce water-based stable carbon nano colloid (CNC) without adding any surfactants at the room temperature. The physical, chemical, and thermal properties of CNC prepared were characterized by using various techniques, such as particle size analyzer, zeta potential meter, TEM, XRD, FT-IR, turbidity meter, viscometer, and transient hot-wire method. The average primary size of the suspended spherical-shaped nanoparticles in the CNC was found to be {approx}15 nm in diameter. The thermal conductivity of CNC compared with that of water was observed to increase up to {approx}14% with the CNC concentration of {approx}4.2 wt%. The CNC prepared in this study was considerably stable over the period of 600 h. With the assistance of FT-IR spectroscopy analysis, we confirmed the presence of carboxyl group (i.e., O-H stretching (3,458 cm{sup -1}) and C=O stretching (1,712 cm{sup -1})) formed in the outer atomic layer of carbon nanoparticles, which (i) made the carbon particles hydrophilic and (ii) prevented the aggregation among primary nanoparticles by increasing the magnitude of zeta potential over the long period.

  4. Production and characterization of carbon nano colloid via one-step electrochemical method

    International Nuclear Information System (INIS)

    Kim, Doohyun; Hwang, Yujin; Cheong, Seong Ir; Lee, Jae Keun; Hong, Daeseung; Moon, Seongyong; Lee, Jung Eun; Kim, Soo H.

    2008-01-01

    We present a one-step electrochemical method to produce water-based stable carbon nano colloid (CNC) without adding any surfactants at the room temperature. The physical, chemical, and thermal properties of CNC prepared were characterized by using various techniques, such as particle size analyzer, zeta potential meter, TEM, XRD, FT-IR, turbidity meter, viscometer, and transient hot-wire method. The average primary size of the suspended spherical-shaped nanoparticles in the CNC was found to be ∼15 nm in diameter. The thermal conductivity of CNC compared with that of water was observed to increase up to ∼14% with the CNC concentration of ∼4.2 wt%. The CNC prepared in this study was considerably stable over the period of 600 h. With the assistance of FT-IR spectroscopy analysis, we confirmed the presence of carboxyl group (i.e., O-H stretching (3,458 cm -1 ) and C=O stretching (1,712 cm -1 )) formed in the outer atomic layer of carbon nanoparticles, which (i) made the carbon particles hydrophilic and (ii) prevented the aggregation among primary nanoparticles by increasing the magnitude of zeta potential over the long period.

  5. Granulated Silica Method for the Fiber Preform Production

    Directory of Open Access Journals (Sweden)

    Sönke Pilz

    2017-07-01

    Full Text Available During the past few years, we have studied the granulated silica method as a versatile and cost effective way of fiber preform production and the sol-gel method. Until now, we have used the sol-gel technology together with an iterative re-melting and milling step in order to produce rare earth or transition metal doped granular material for the granulated silica method. Here, we present that the iterative re-melting (laser-assisted and milling step is no longer needed to reach a high homogeneity. The sol-gel method also offers a high degree of compositional flexibility with respect to dopants; it further facilitates achieving high concentrations, even in cases when several dopants are used. We employed optical active doped sol-gel derived granulate for the fiber core, whereas pure or index-raised granulated silica has been employed for the cladding. Based on the powder-in-tube technique, where silica glass tubes are appropriately filled with these granular materials, fibers has been directly drawn (“fiber rapid prototyping”, or eventually after an additional optional quality enhancing vitrification step. The powder-in-tube technique is also ideally suited for the preparation of microstructured optical fibers.

  6. EVALUATION OF THE ANTIGENICITY AND IMMUNOGENICITY OF Eimeria tenella BY REPRODUCTIVE INDEX AND HISTOPATHOLOGICAL CHANGES OF CECAL COCCIDIOSIS VIRULENT LIVE VACCINE IN BROILER CHICKENS.

    Science.gov (United States)

    Suprihati, Endang; Yunus, Muchammad

    2018-01-01

    The development of vaccine to control coccidiosis caused by Eimeria tenella ( E. tenella ) in chickens is intensifying because of the increasing threat of drug resistance to anticoccidial agents. It is important, therefore, to develop a reliable standard method for the assessment of vaccine afficacy particularly antigenicity and immunogenicity become crucial. Evaluation of E. tenella antigenicity and immunogenicity to some low doses can be reflected by reproductive index and histopathological changes. The complete random design of research was used in this study. Sixty of two weeks old broilers were divided into four groups and each group composed 15 replications. The group 1 was chicken group without virulent E. tenella oocyst inoculation. The group 2, 3 and group 4 were chicken group inoculated with virulent E. tenella oocyst at doses of 1.0 x 10 2 , 2.0 x 10 2 , 3.0 x 10 2 , respectively. Then all chicken groups were challenged with E. tenella oocyst at doses of 1.0 x 10 3 . Observation of research that represented antigenicity and immunogenicity was clinical sign, reproductive index, histopathological changes. On virulent E. tenella inoculation step, some clinical signs such as appetite, weakness, and diarrhea were very slight on all chicken groups. While on challenge test step, there were no clinical signs of all chicken groups except the group 1. For the reproductive index of virulent E. tenella inoculation step, there were no significantly differences in all chicken groups except the group 1. As reproductive index, the same result pattern was seen for histopathological changes. The low number virulent E. tenella had low reproductive index and few histopathological changes effect that represents a promising strategy to prevent cecal coccidiosis in chickens.

  7. ESTIMATE OF STAND DENSITY INDEX FOR EUCALYPTUS UROPHYLLA USING DIFFERENT FIT METHODS

    Directory of Open Access Journals (Sweden)

    Ernani Lopes Possato

    Full Text Available ABSTRACT The Reineke stand density index (SDI was created on 1933 and remains as target of researches due to its importance on helping decision making regarding the management of population density. Part of such works is focused on the manner by which plots were selected and methods for the fit of Reineke model parameters in order to improve the definition of SDI value for the genetic material evaluated. The present study aimed to estimate the SDI value for Eucalyptus urophylla using the Reineke model fitted by the method of linear regression (LR and stochastic frontier analysis (SFA. The database containing pairs of data number of stems per hectare (N and mean quadratic diameter (Dq was selected in three intensities, containing the 8, 30 and 43 plots of greatest density, and models were fitted by LR and SFA on each selected intensities. The intensity of data selection altered slightly the estimates of parameters and SDI when comparing the fits of each method. On the other hand, the adjust method influenced the mean estimated values of slope and SDI, which corresponded to -1.863 and 740 for LR and -1.582 and 810 for SFA.

  8. Quality assurance: using the exposure index and the deviation index to monitor radiation exposure for portable chest radiographs in neonates

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Mervyn D. [Indiana University School of Medicine, Department of Radiology, Riley Children' s Hospital, Indianapolis, IN (United States); Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States); Cooper, Matt L.; Piersall, Kelly [Indiana University School of Medicine, Department of Radiology, Riley Children' s Hospital, Indianapolis, IN (United States); Apgar, Bruce K. [Agfa HealthCare Corporation, Greenville, SC (United States)

    2011-05-15

    Many methods are used to track patient exposure during acquisition of plain film radiographs. A uniform international standard would aid this process. To evaluate and describe a new, simple quality-assurance method for monitoring patient exposure. This method uses the ''exposure index'' and the ''deviation index,'' recently developed by the International Electrotechnical Commission (IEC) and American Association of Physicists in Medicine (AAPM). The deviation index measures variation from an ideal target exposure index value. Our objective was to determine whether the exposure index and the deviation index can be used to monitor and control exposure drift over time. Our Agfa workstation automatically keeps a record of the exposure index for every patient. The exposure index and deviation index were calculated on 1,884 consecutive neonatal chest images. Exposure of a neonatal chest phantom was performed as a control. Acquisition of the exposure index and calculation of the deviation index was easily achieved. The weekly mean exposure index of the phantom and the patients was stable and showed <10% change during the study, indicating no exposure drift during the study period. The exposure index is an excellent tool to monitor the consistency of patient exposures. It does not indicate the exposure value used, but is an index to track compliance with a pre-determined target exposure. (orig.)

  9. Quality assurance: using the exposure index and the deviation index to monitor radiation exposure for portable chest radiographs in neonates

    International Nuclear Information System (INIS)

    Cohen, Mervyn D.; Cooper, Matt L.; Piersall, Kelly; Apgar, Bruce K.

    2011-01-01

    Many methods are used to track patient exposure during acquisition of plain film radiographs. A uniform international standard would aid this process. To evaluate and describe a new, simple quality-assurance method for monitoring patient exposure. This method uses the ''exposure index'' and the ''deviation index,'' recently developed by the International Electrotechnical Commission (IEC) and American Association of Physicists in Medicine (AAPM). The deviation index measures variation from an ideal target exposure index value. Our objective was to determine whether the exposure index and the deviation index can be used to monitor and control exposure drift over time. Our Agfa workstation automatically keeps a record of the exposure index for every patient. The exposure index and deviation index were calculated on 1,884 consecutive neonatal chest images. Exposure of a neonatal chest phantom was performed as a control. Acquisition of the exposure index and calculation of the deviation index was easily achieved. The weekly mean exposure index of the phantom and the patients was stable and showed <10% change during the study, indicating no exposure drift during the study period. The exposure index is an excellent tool to monitor the consistency of patient exposures. It does not indicate the exposure value used, but is an index to track compliance with a pre-determined target exposure. (orig.)

  10. Cross-cultural adaptation of the Quality of Life Index Spinal Cord Injury - Version III

    Directory of Open Access Journals (Sweden)

    Priscila Alencar Mendes Reis

    2015-06-01

    Full Text Available OBJECTIVE To translate and culturally adapt to Portuguese the Ferrans and Powers Quality of Life Index Spinal Cord Injury - Version III and characterize the sample in relation to sociodemographic and clinical aspects. METHOD A methodological study with view to cross-cultural adaptation, following the particular steps of this method: initial translation, translation synthesis, back-translation (translation back to the original language, review by a committee of judges and pretest of the final version. The pretest was carried out with 30 patients with spinal cord injury. RESULTS An index of 74 items divided into two parts (satisfaction/importance was obtained. The criteria of semantic equivalence were evaluated as very adequate translation, higher than 87%, and vocabulary and were grammar higher than 86%. Idiomatic equivalence was higher than 74%, experimental greater than 78% and conceptual was greater than 70%. CONCLUSION After cross-cultural adaptation, the instrument proved semantic, idiomatic, experimental and conceptual adequacy, in addition to helping the evaluation of the quality of life of people with spinal cord injury.

  11. Determination of the maximum-depth to potential field sources by a maximum structural index method

    Science.gov (United States)

    Fedi, M.; Florio, G.

    2013-01-01

    A simple and fast determination of the limiting depth to the sources may represent a significant help to the data interpretation. To this end we explore the possibility of determining those source parameters shared by all the classes of models fitting the data. One approach is to determine the maximum depth-to-source compatible with the measured data, by using for example the well-known Bott-Smith rules. These rules involve only the knowledge of the field and its horizontal gradient maxima, and are independent from the density contrast. Thanks to the direct relationship between structural index and depth to sources we work out a simple and fast strategy to obtain the maximum depth by using the semi-automated methods, such as Euler deconvolution or depth-from-extreme-points method (DEXP). The proposed method consists in estimating the maximum depth as the one obtained for the highest allowable value of the structural index (Nmax). Nmax may be easily determined, since it depends only on the dimensionality of the problem (2D/3D) and on the nature of the analyzed field (e.g., gravity field or magnetic field). We tested our approach on synthetic models against the results obtained by the classical Bott-Smith formulas and the results are in fact very similar, confirming the validity of this method. However, while Bott-Smith formulas are restricted to the gravity field only, our method is applicable also to the magnetic field and to any derivative of the gravity and magnetic field. Our method yields a useful criterion to assess the source model based on the (∂f/∂x)max/fmax ratio. The usefulness of the method in real cases is demonstrated for a salt wall in the Mississippi basin, where the estimation of the maximum depth agrees with the seismic information.

  12. Simulation of the two-fluid model on incompressible flow with Fractional Step method for both resolved and unresolved scale interfaces

    International Nuclear Information System (INIS)

    Hou, Xiaofei; Rigola, Joaquim; Lehmkuhl, Oriol; Oliva, Assensi

    2015-01-01

    Highlights: • Two phase flow with free surface is solved by means of two-fluid model (TFM). • Fractional Step method and finite volume technique is used to solve TFM. • Conservative Level Set method reduces interface sharpening diffusion problem. • Cases including high density ratios and high viscosities validate the models. - Abstract: In the present paper, the Fractional Step method usually used in single fluid flow is here extended and applied for the two-fluid model resolution using the finite volume discretization. The use of a projection method resolution instead of the usual pressure-correction method for multi-fluid flow, successfully avoids iteration processes. On the other hand, the main weakness of the two fluid model used for simulations of free surface flows, which is the numerical diffusion of the interface, is also solved by means of the conservative Level Set method (interface sharpening) (Strubelj et al., 2009). Moreover, the use of the algorithm proposed has allowed presenting different free-surface cases with or without Level Set implementation even under coarse meshes under a wide range of density ratios. Thus, the numerical results presented, numerically verified, experimentally validated and converged under high density ratios, shows the capability and reliability of this resolution method for both mixed and unmixed flows

  13. Gamma-index method sensitivity for gauging plan delivery accuracy of volumetric modulated arc therapy.

    Science.gov (United States)

    Park, Jong In; Park, Jong Min; Kim, Jung-In; Park, So-Yeon; Ye, Sung-Joon

    2015-12-01

    The aim of this study was to investigate the sensitivity of the gamma-index method according to various gamma criteria for volumetric modulated arc therapy (VMAT). Twenty head and neck (HN) and twenty prostate VMAT plans were retrospectively selected for this study. Both global and local 2D gamma evaluations were performed with criteria of 3%/3 mm, 2%/2 mm, 1%/2 mm and 2%/1 mm. In this study, the global and local gamma-index calculated the differences in doses relative to the maximum dose and the dose at the current measurement point, respectively. Using log files acquired during delivery, the differences in parameters at every control point between the VMAT plans and the log files were acquired. The differences in dose-volumetric parameters between reconstructed VMAT plans using the log files and the original VMAT plans were calculated. The Spearman's rank correlation coefficients (rs) were calculated between the passing rates and those differences. Considerable correlations with statistical significances were observed between global 1%/2 mm, local 1%/2 mm and local 2%/1 mm and the MLC position differences (rs = -0.712, -0.628 and -0.581). The numbers of rs values with statistical significance between the passing rates and the changes in dose-volumetric parameters were largest in global 2%/2 mm (n = 16), global 2%/1 mm (n = 15) and local 2%/1 mm (n = 13) criteria. Local gamma-index method with 2%/1 mm generally showed higher sensitivity to detect deviations between a VMAT plan and the delivery of the VMAT plan. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  14. Analytical considerations for the use of the paleothermometer tetraether index(86) and the branched vs isoprenoid tetraether index regarding the choice of cleanup and instrumental conditions.

    Science.gov (United States)

    Escala, Marina; Fietz, Susanne; Rueda, Gemma; Rosell-Melé, Antoni

    2009-04-01

    The tetraether index of tetraethers consisting of 86 carbons (TEX(86)) is a novel proxy applied to obtain paleotemperature reconstructions from marine and lacustrine settings. It is usually applied alongside the branched vs isoprenoid tetraether (BIT) index, which provides paleoenvironmental information as well as information on the reliability of TEX(86). Both indices are calculated via the analysis of glycerol dialkyl glycerol tetraethers or GDGTs by means of high-performance liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry (HPLC/APCI-MS). Here we test the performance of alternative methods for sample cleanup and instrumental analysis. In particular, we evaluate using alkaline hydrolysis as an alternative cleanup step to alumina column fractionation and show that the resulting TEX(86) and BIT are statistically equivalent. We also test two different adsorbents in the activated or deactivated state for preparative column fractionation and show that any of them can be used to measure TEX(86) but that a certain discrimination between GDGTs used in the BIT index can occur. Regarding the mass spectrometer design, an ion-trap is shown to be as precise as a quadrupole mass spectrometer for GDGT analysis. Some differences are observed for TEX(86) and especially for BIT values obtained from both MS designs. We provide evidence that the APCI conditions are at least partly responsible for these differences. We recommend caution when comparing BIT values among laboratories as this index seems to be especially sensitive to analytical conditions.

  15. Effects of Swelling Processes on the Particle Morphology of Porous P(MMA-EGDMA) Particles via Seeded Two-step Swelling Method

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    1 Results Porous functional polymer particles have been drawing great interest for their applications in many fields such as ion exchange,polymeric carrier,biomedicine,biochemistry,cosmetics,plastic pigments,and were first prepared by suspension polymerization in 1 950 s.Since 1990's,some approaches such as seeded emulsion polymerization method,dynamic monomer swelling method,activated swelling method and multi-step seeded method[1-4] have been used by many researchers to synthesize this kind of polymer...

  16. Towards cheminformatics-based estimation of drug therapeutic index: Predicting the protective index of anticonvulsants using a new quantitative structure-index relationship approach.

    Science.gov (United States)

    Chen, Shangying; Zhang, Peng; Liu, Xin; Qin, Chu; Tao, Lin; Zhang, Cheng; Yang, Sheng Yong; Chen, Yu Zong; Chui, Wai Keung

    2016-06-01

    The overall efficacy and safety profile of a new drug is partially evaluated by the therapeutic index in clinical studies and by the protective index (PI) in preclinical studies. In-silico predictive methods may facilitate the assessment of these indicators. Although QSAR and QSTR models can be used for predicting PI, their predictive capability has not been evaluated. To test this capability, we developed QSAR and QSTR models for predicting the activity and toxicity of anticonvulsants at accuracy levels above the literature-reported threshold (LT) of good QSAR models as tested by both the internal 5-fold cross validation and external validation method. These models showed significantly compromised PI predictive capability due to the cumulative errors of the QSAR and QSTR models. Therefore, in this investigation a new quantitative structure-index relationship (QSIR) model was devised and it showed improved PI predictive capability that superseded the LT of good QSAR models. The QSAR, QSTR and QSIR models were developed using support vector regression (SVR) method with the parameters optimized by using the greedy search method. The molecular descriptors relevant to the prediction of anticonvulsant activities, toxicities and PIs were analyzed by a recursive feature elimination method. The selected molecular descriptors are primarily associated with the drug-like, pharmacological and toxicological features and those used in the published anticonvulsant QSAR and QSTR models. This study suggested that QSIR is useful for estimating the therapeutic index of drug candidates. Copyright © 2016. Published by Elsevier Inc.

  17. Third-order-accurate numerical methods for efficient, large time-step solutions of mixed linear and nonlinear problems

    Energy Technology Data Exchange (ETDEWEB)

    Cobb, J.W.

    1995-02-01

    There is an increasing need for more accurate numerical methods for large-scale nonlinear magneto-fluid turbulence calculations. These methods should not only increase the current state of the art in terms of accuracy, but should also continue to optimize other desired properties such as simplicity, minimized computation, minimized memory requirements, and robust stability. This includes the ability to stably solve stiff problems with long time-steps. This work discusses a general methodology for deriving higher-order numerical methods. It also discusses how the selection of various choices can affect the desired properties. The explicit discussion focuses on third-order Runge-Kutta methods, including general solutions and five examples. The study investigates the linear numerical analysis of these methods, including their accuracy, general stability, and stiff stability. Additional appendices discuss linear multistep methods, discuss directions for further work, and exhibit numerical analysis results for some other commonly used lower-order methods.

  18. A step-by-step guide to systematically identify all relevant animal studies

    Science.gov (United States)

    Leenaars, Marlies; Hooijmans, Carlijn R; van Veggel, Nieky; ter Riet, Gerben; Leeflang, Mariska; Hooft, Lotty; van der Wilt, Gert Jan; Tillema, Alice; Ritskes-Hoitinga, Merel

    2012-01-01

    Before starting a new animal experiment, thorough analysis of previously performed experiments is essential from a scientific as well as from an ethical point of view. The method that is most suitable to carry out such a thorough analysis of the literature is a systematic review (SR). An essential first step in an SR is to search and find all potentially relevant studies. It is important to include all available evidence in an SR to minimize bias and reduce hampered interpretation of experimental outcomes. Despite the recent development of search filters to find animal studies in PubMed and EMBASE, searching for all available animal studies remains a challenge. Available guidelines from the clinical field cannot be copied directly to the situation within animal research, and although there are plenty of books and courses on searching the literature, there is no compact guide available to search and find relevant animal studies. Therefore, in order to facilitate a structured, thorough and transparent search for animal studies (in both preclinical and fundamental science), an easy-to-use, step-by-step guide was prepared and optimized using feedback from scientists in the field of animal experimentation. The step-by-step guide will assist scientists in performing a comprehensive literature search and, consequently, improve the scientific quality of the resulting review and prevent unnecessary animal use in the future. PMID:22037056

  19. Variable order one-step methods for initial value problems I ...

    African Journals Online (AJOL)

    A class of variable order one-step integrators is proposed for Initial Value Problems (IVPs) in Ordinary Differential Equations (ODEs). It is based on a rational interpolant. Journal of the Nigerian Association of Mathematical Physics Vol. 10 2006: pp. 91-96 ...

  20. Indexation and causation of financial markets

    CERN Document Server

    Tanokura, Yoko

    2015-01-01

    This book presents a new statistical method of constructing a price index of a financial asset where the price distributions are skewed and heavy-tailed and investigates the effectiveness of the method. In order to fully reflect the movements of prices or returns on a financial asset, the index should reflect their distributions. However, they are often heavy-tailed and possibly skewed, and identifying them directly is not easy. This book first develops an index construction method depending on the price distributions, by using nonstationary time series analysis. Firstly, the long-term trend of the distributions of the optimal Box–Cox transformed prices is estimated by fitting a trend model with time-varying observation noises. By applying state space modeling, the estimation is performed and missing observations are automatically interpolated. Finally, the index is defined by taking the inverse Box–Cox transformation of the optimal long-term trend. This book applies the method to various financial data. ...

  1. Morphology-photovoltaic property correlation in perovskite solar cells: One-step versus two-step deposition of CH3NH3PbI3

    Directory of Open Access Journals (Sweden)

    Jeong-Hyeok Im

    2014-08-01

    Full Text Available Perovskite CH3NH3PbI3 light absorber is deposited on the mesoporous TiO2 layer via one-step and two-step coating methods and their photovoltaic performances are compared. One-step coating using a solution containing CH3NH3I and PbI2 shows average power conversion efficiency (PCE of 7.5%, while higher average PCE of 13.9% is obtained from two-step coating method, mainly due to higher voltage and fill factor. The coverage, pore-filling, and morphology of the deposited perovskite are found to be critical in photovoltaic performance of the mesoporous TiO2 based perovskite solar cells.

  2. A method for developing a large-scale sediment yield index for European river basins

    Energy Technology Data Exchange (ETDEWEB)

    Delmas, Magalie; Cerdan, Olivier; Garcin, Manuel [BRGM ARN/ESL, Orleans (France); Mouchel, Jean-Marie [UMR Sisyphe, Univ. P and M Curie, Paris (France)

    2009-12-15

    Background, aim, and scope: Sediment fluxes within continental areas play a major role in biogeochemical cycles and are often the cause of soil surface degradation as well as water and ecosystem pollution. In a situation where a high proportion of the land surface is experiencing significant global land use and climate changes, it appears important to establish sediment budgets considering the major processes forcing sediment redistribution within drainage areas. In this context, the aim of this study is to test a methodology to estimate a sediment yield index at a large spatial resolution for European river basins. Data and methods: Four indicators representing processes respectively considered as sources (mass movement and hillslope erosion), sinks (deposits), and transfers of sediments (drainage density) are defined using distributed data. Using these indicators we propose a basic conceptual approach to test the possibility of explaining sediment yield observed at the outlet of 29 selected European river basins. We propose an index which adds the two sources and transfers, and subsequently subtracts the sink term. This index is then compared to observed sediment yield data. Results: With this approach, variability between river basins is observed and the evolution of each indicator analyzed. A linear regression shows a correlation coefficient of 0.83 linking observed specific sediment yield (SSY) with the SSY index. Discussion: To improve this approach at this large river basin scale, basin classification is further refined using the relation between the observed SSY and the index obtained from the four indicators. It allows a refinement of the results. Conclusions: This study presents a conceptual approach offering the advantages of using spatially distributed data combined with major sediment redistribution processes to estimate the sediment yield observed at the outlet of river basins. Recommendations and perspectives: Inclusion of better information on

  3. Comparing 3 dietary pattern methods--cluster analysis, factor analysis, and index analysis--With colorectal cancer risk: The NIH-AARP Diet and Health Study.

    Science.gov (United States)

    Reedy, Jill; Wirfält, Elisabet; Flood, Andrew; Mitrou, Panagiota N; Krebs-Smith, Susan M; Kipnis, Victor; Midthune, Douglas; Leitzmann, Michael; Hollenbeck, Albert; Schatzkin, Arthur; Subar, Amy F

    2010-02-15

    The authors compared dietary pattern methods-cluster analysis, factor analysis, and index analysis-with colorectal cancer risk in the National Institutes of Health (NIH)-AARP Diet and Health Study (n = 492,306). Data from a 124-item food frequency questionnaire (1995-1996) were used to identify 4 clusters for men (3 clusters for women), 3 factors, and 4 indexes. Comparisons were made with adjusted relative risks and 95% confidence intervals, distributions of individuals in clusters by quintile of factor and index scores, and health behavior characteristics. During 5 years of follow-up through 2000, 3,110 colorectal cancer cases were ascertained. In men, the vegetables and fruits cluster, the fruits and vegetables factor, the fat-reduced/diet foods factor, and all indexes were associated with reduced risk; the meat and potatoes factor was associated with increased risk. In women, reduced risk was found with the Healthy Eating Index-2005 and increased risk with the meat and potatoes factor. For men, beneficial health characteristics were seen with all fruit/vegetable patterns, diet foods patterns, and indexes, while poorer health characteristics were found with meat patterns. For women, findings were similar except that poorer health characteristics were seen with diet foods patterns. Similarities were found across methods, suggesting basic qualities of healthy diets. Nonetheless, findings vary because each method answers a different question.

  4. Peyton’s four-step approach: differential effects of single instructional steps on procedural and memory performance – a clarification study

    Directory of Open Access Journals (Sweden)

    Krautter M

    2015-05-01

    Full Text Available Markus Krautter,1 Ronja Dittrich,2 Annette Safi,2 Justine Krautter,1 Imad Maatouk,2 Andreas Moeltner,2 Wolfgang Herzog,2 Christoph Nikendei2 1Department of Nephrology, 2Department of General Internal and Psychosomatic Medicine, University of Heidelberg Medical Hospital, Heidelberg, Germany Background: Although Peyton’s four-step approach is a widely used method for skills-lab training in undergraduate medical education and has been shown to be more effective than standard instruction, it is unclear whether its superiority can be attributed to a specific single step. Purpose: We conducted a randomized controlled trial to investigate the differential learning outcomes of the separate steps of Peyton’s four-step approach. Methods: Volunteer medical students were randomly assigned to four different groups. Step-1 group received Peyton’s Step 1, Step-2 group received Peyton’s Steps 1 and 2, Step-3 group received Peyton’s Steps 1, 2, and 3, and Step-3mod group received Peyton’s Steps 1 and 2, followed by a repetition of Step 2. Following the training, the first independent performance of a central venous catheter (CVC insertion using a manikin was video-recorded and scored by independent video assessors using binary checklists. The day after the training, memory performance during delayed recall was assessed with an incidental free recall test. Results: A total of 97 participants agreed to participate in the trial. There were no statistically significant group differences with regard to age, sex, completed education in a medical profession, completed medical clerkships, preliminary memory tests, or self-efficacy ratings. Regarding checklist ratings, Step-2 group showed a superior first independent performance of CVC placement compared to Step-1 group (P<0.001, and Step-3 group showed a superior performance to Step-2 group (P<0.009, while Step-2 group and Step-3mod group did not differ (P=0.055. The findings were similar in the incidental

  5. Effect of two-step and one-step surface conditioning of glass ceramic on adhesion strength of orthodontic bracket and effect of thermo-cycling on adhesion strength.

    Science.gov (United States)

    Asiry, Moshabab A; AlShahrani, Ibrahim; Alaqeel, Samer M; Durgesh, Bangalore H; Ramakrishnaiah, Ravikumar

    2018-08-01

    The adhesion strength of orthodontic brackets bonded to dental glass ceramics was evaluated after ceramic surface was treated with two-step and one-step surface conditioning systems, and subjecting to thermo-cycling. A total of forty specimens were fabricated from silica based glass ceramic (lithium disilicate) by duplicating the buccal surface of maxillary first premolar. The specimens were randomly assigned to two experimental groups (n = 20), group one specimens were treated with two-step surface conditioning system (IPS ceramic etching gel™ and Monobond plus™) and group two specimens were treated with one-step surface conditioning system (Monobond etch and prime™). The surface roughness of the specimens after treatment with two-step and one-step surface conditioning system was measured using non-contact surface profilometer. Ten randomly selected specimens from each group were subjected to thermo-cycling and the remaining ten served as baseline. The shear bond strength of the specimens was measured using universal material testing machine. The adhesive remnant index score was calculated, and the results of surface roughness and bond strength were tabulated and subjected to analysis of variance and post hoc tukey's test at a significance level of p step conditioning system had higher surface roughness and bond strength than one-step conditioning system. The majority of the specimens treated with both two-step and one-step conditioned specimens showed adhesive failure after subjecting thermo-cycling. Traditional two-step conditioning provides better bond strength. The clinical importance of the study is that, the silane promoted adhesion significantly reduces on exposure to thermo-cycling. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Simulation Opportunity Index, A Simple and Effective Method to Boost the Hydrocarbon Recovery

    KAUST Repository

    Saputra, Wardana

    2016-09-08

    During periods of low oil prices, profitability of field developments drops drastically. To help with this difficulty, a cost-effective method has been proposed to boost the hydrocarbon recovery by optimizing well locations through the Simulated Opportunity Index (SOI). SOI is an intelligent method to identify zones with high potential for production which is empirically calculated from basic rock and fluid properties, and from reservoir pressure as its energy capacity. In order to obtain the best results, the original SOI formula (Molina et al., 2009) was extended to both oil and gas fields. Based on this modified SOI formula, a software program has been developed to locate the best well locations considering multilayer, existing wells, and fault existences. This paper describes how the SOI software helps as a simple, fast, and accurate way to obtain the higher hydrocarbon production than that of trial-error method and previous studies in two different fields located in offshore Indonesia. On one hand, the proposed method could save money by minimizing the required number of wells. On the other hand, it could maximize profit by maximizing recovery.

  7. Evaluation of real-time ice concentration inside pipeline by the refractive index method

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Gyu; Kang, Chae Dong [Chonbuk National University, Jeonju (Korea, Republic of); Chung, Dong Yeol; Peck, Jong Hyeon [KITECH, Cheonan (Korea, Republic of)

    2015-05-15

    Ice fraction (or ice concentration, IC) of the ice slurry flowing through the pipe is very difficult to measure directly and in real time in ice slurry type system in thermal energy storage system. Measuring IC is very important to calculate the capacity of cold energy supplied through a pipeline. Ice fraction measurement methods have been reported as using density, electric resistance, electric conductivity, freezing point etc. However, the conventional methods are not perfect in terms of the resolution and accuracy. In this study, a new method is suggested to measure the IC of the ice slurry flowing through a pipe, which is used for a refractometer with low electrical noise and high resolution. To measure IC of the flowing ice slurry aqueous solution in pipe, it was installed in the test section to mass flow meter, refractometer, cyclone, and RTD Resistance temperature detector) sensor. From the experiment, IC measurement method by using refractive index showed better result than others for the ice slurry in pipeline flowing or slurry tank.

  8. Qualification test of few group constants generated from an MC method by the two-step neutronics analysis system McCARD/MASTER

    International Nuclear Information System (INIS)

    Park, Ho Jin; Shim, Hyung Jin; Joo, Han Gyu; Kim, Chang Hyo

    2011-01-01

    The purpose of this paper is to examine the qualification of few group constants estimated by the Seoul National University Monte Carlo particle transport analysis code McCARD in terms of core neutronics analyses and thus to validate the McCARD method as a few group constant generator. The two- step core neutronics analyses are conducted for a mini and a realistic PWR by the McCARD/MASTER code system in which McCARD is used as an MC group constant generation code and MASTER as a diffusion core analysis code. The two-step calculations for the effective multiplication factors and assembly power distributions of the two PWR cores by McCARD/MASTER are compared with the reference McCARD calculations. By showing excellent agreements between McCARD/MASTER and the reference MC core neutronics analyses for the two PWRs, it is concluded that the MC method implemented in McCARD can generate few group constants which are well qualified for high-accuracy two-step core neutronics calculations. (author)

  9. Designing Alternative Transport Methods for the Distributed Data Collection of ATLAS EventIndex Project

    CERN Document Server

    Fernandez Casani, Alvaro; The ATLAS collaboration

    2016-01-01

    One of the key and challenging tasks of the ATLAS EventIndex project is to index and catalog all the produced events not only at CERN but also at hundreds of worldwide grid sites, and convey the data in real time to a central Hadoop instance at CERN. While this distributed data collection is currently operating correctly in production, there are some issues that might impose performance bottlenecks in the future, with an expected rise in the event production and reprocessing rates. In this work, we first describe the current approach based on a messaging system, which conveys the data from the sources to the central catalog, and we identify some weaknesses of this system. Then, we study a promising alternative transport method based on an object store, presenting a performance comparison with the current approach, and the architectural design changes needed to adapt the system to the next run of the ATLAS experiment at CERN.

  10. Influence of refraction index strength on the light propagation in dielectrics material with periodic refraction index

    International Nuclear Information System (INIS)

    Hidayat, Arif; Latifah, Eny; Kurniati, Diana; Wisodo, Hari

    2016-01-01

    This study investigated the influence of refraction index strength on the light propagation in refraction index-varied dielectric material. This dielectric material served as photonic lattice. The behavior of light propagation influenced by variation of refraction index in photonic lattice was investigated. Modes of the guiding light were determined numerically using squared-operator iteration method. It was found that the greater the strength of refraction index, the smaller the guiding modes.

  11. Self-Adaptive Step Firefly Algorithm

    Directory of Open Access Journals (Sweden)

    Shuhao Yu

    2013-01-01

    Full Text Available In the standard firefly algorithm, each firefly has the same step settings and its values decrease from iteration to iteration. Therefore, it may fall into the local optimum. Furthermore, the decreasing of step is restrained by the maximum of iteration, which has an influence on the convergence speed and precision. In order to avoid falling into the local optimum and reduce the impact of the maximum of iteration, a self-adaptive step firefly algorithm is proposed in the paper. Its core idea is setting the step of each firefly varying with the iteration, according to each firefly’s historical information and current situation. Experiments are made to show the performance of our approach compared with the standard FA, based on sixteen standard testing benchmark functions. The results reveal that our method can prevent the premature convergence and improve the convergence speed and accurateness.

  12. Properties of nano-structured Ni/YSZ anodes fabricated from plasma sprayable NiO/YSZ powder prepared by single step solution combustion method

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, B. Shri; Balaji, N.; Kumar, S. Senthil; Aruna, S.T., E-mail: staruna194@gmail.com

    2016-12-15

    Highlights: • Preparation of plasma grade NiO/YSZ powder in single step. • Fabrication of nano-structured Ni/YSZ coating. • Conductivity of 600 S/cm at 800 °C. - Abstract: NiO/YSZ anode coatings are fabricated by atmospheric plasma spraying at different plasma powers from plasma grade NiO/YSZ powders that are prepared in a single step by solution combustion method. The process adopted is devoid of multi-steps that are generally involved in conventional spray drying or fusing and crushing methods. Density of the coating increased and porosity decreased with increase in the plasma power of deposition. An ideal nano-structured Ni/YSZ anode encompassing nano YSZ particles, nano Ni particles and nano pores is achieved on reducing the coating deposited at lower plasma powers. The coating exhibit porosities in the range of 27%, sufficient for anode functional layers. Electronic conductivity of the coatings is in the range of 600 S/cm at 800 °C.

  13. Modified Pressure-Correction Projection Methods: Open Boundary and Variable Time Stepping

    KAUST Repository

    Bonito, Andrea

    2014-10-31

    © Springer International Publishing Switzerland 2015. In this paper, we design and study two modifications of the first order standard pressure increment projection scheme for the Stokes system. The first scheme improves the existing schemes in the case of open boundary condition by modifying the pressure increment boundary condition, thereby minimizing the pressure boundary layer and recovering the optimal first order decay. The second scheme allows for variable time stepping. It turns out that the straightforward modification to variable time stepping leads to unstable schemes. The proposed scheme is not only stable but also exhibits the optimal first order decay. Numerical computations illustrating the theoretical estimates are provided for both new schemes.

  14. Modified Pressure-Correction Projection Methods: Open Boundary and Variable Time Stepping

    KAUST Repository

    Bonito, Andrea; Guermond, Jean-Luc; Lee, Sanghyun

    2014-01-01

    © Springer International Publishing Switzerland 2015. In this paper, we design and study two modifications of the first order standard pressure increment projection scheme for the Stokes system. The first scheme improves the existing schemes in the case of open boundary condition by modifying the pressure increment boundary condition, thereby minimizing the pressure boundary layer and recovering the optimal first order decay. The second scheme allows for variable time stepping. It turns out that the straightforward modification to variable time stepping leads to unstable schemes. The proposed scheme is not only stable but also exhibits the optimal first order decay. Numerical computations illustrating the theoretical estimates are provided for both new schemes.

  15. Morse Set Classification and Hierarchical Refinement Using Conley Index

    KAUST Repository

    Guoning Chen,; Qingqing Deng,; Szymczak, A.; Laramee, R. S.; Zhang, E.

    2012-01-01

    Morse decomposition provides a numerically stable topological representation of vector fields that is crucial for their rigorous interpretation. However, Morse decomposition is not unique, and its granularity directly impacts its computational cost. In this paper, we propose an automatic refinement scheme to construct the Morse Connection Graph (MCG) of a given vector field in a hierarchical fashion. Our framework allows a Morse set to be refined through a local update of the flow combinatorialization graph, as well as the connection regions between Morse sets. The computation is fast because the most expensive computation is concentrated on a small portion of the domain. Furthermore, the present work allows the generation of a topologically consistent hierarchy of MCGs, which cannot be obtained using a global method. The classification of the extracted Morse sets is a crucial step for the construction of the MCG, for which the Poincar index is inadequate. We make use of an upper bound for the Conley index, provided by the Betti numbers of an index pair for a translation along the flow, to classify the Morse sets. This upper bound is sufficiently accurate for Morse set classification and provides supportive information for the automatic refinement process. An improved visualization technique for MCG is developed to incorporate the Conley indices. Finally, we apply the proposed techniques to a number of synthetic and real-world simulation data to demonstrate their utility. © 2006 IEEE.

  16. Morse Set Classification and Hierarchical Refinement Using Conley Index

    KAUST Repository

    Guoning Chen,

    2012-05-01

    Morse decomposition provides a numerically stable topological representation of vector fields that is crucial for their rigorous interpretation. However, Morse decomposition is not unique, and its granularity directly impacts its computational cost. In this paper, we propose an automatic refinement scheme to construct the Morse Connection Graph (MCG) of a given vector field in a hierarchical fashion. Our framework allows a Morse set to be refined through a local update of the flow combinatorialization graph, as well as the connection regions between Morse sets. The computation is fast because the most expensive computation is concentrated on a small portion of the domain. Furthermore, the present work allows the generation of a topologically consistent hierarchy of MCGs, which cannot be obtained using a global method. The classification of the extracted Morse sets is a crucial step for the construction of the MCG, for which the Poincar index is inadequate. We make use of an upper bound for the Conley index, provided by the Betti numbers of an index pair for a translation along the flow, to classify the Morse sets. This upper bound is sufficiently accurate for Morse set classification and provides supportive information for the automatic refinement process. An improved visualization technique for MCG is developed to incorporate the Conley indices. Finally, we apply the proposed techniques to a number of synthetic and real-world simulation data to demonstrate their utility. © 2006 IEEE.

  17. Stepping movement analysis of control rod drive mechanism

    International Nuclear Information System (INIS)

    Xu Yantao; Zu Hongbiao

    2013-01-01

    Background: Control rod drive mechanism (CRDM) is one of the important safety-related equipment for nuclear power plants. Purpose: The operating parameters of stepping movement, including lifting loads, step distance and step velocity, are all critical design targets. Methods: FEA and numerical simulation are used to analyze stepping movement separately. Results: The motion equations of the movable magnet in stepping movement are established by load analysis. Gravitation, magnetic force, fluid resistance and spring force are all in consideration in the load analysis. The operating parameters of stepping movement are given. Conclusions: The results, including time history curves of force, speed and etc, can positively used in the design of CRDM. (authors)

  18. Toward the prediction of class I and II mouse major histocompatibility complex-peptide-binding affinity: in silico bioinformatic step-by-step guide using quantitative structure-activity relationships.

    Science.gov (United States)

    Hattotuwagama, Channa K; Doytchinova, Irini A; Flower, Darren R

    2007-01-01

    Quantitative structure-activity relationship (QSAR) analysis is a cornerstone of modern informatics. Predictive computational models of peptide-major histocompatibility complex (MHC)-binding affinity based on QSAR technology have now become important components of modern computational immunovaccinology. Historically, such approaches have been built around semiqualitative, classification methods, but these are now giving way to quantitative regression methods. We review three methods--a 2D-QSAR additive-partial least squares (PLS) and a 3D-QSAR comparative molecular similarity index analysis (CoMSIA) method--which can identify the sequence dependence of peptide-binding specificity for various class I MHC alleles from the reported binding affinities (IC50) of peptide sets. The third method is an iterative self-consistent (ISC) PLS-based additive method, which is a recently developed extension to the additive method for the affinity prediction of class II peptides. The QSAR methods presented here have established themselves as immunoinformatic techniques complementary to existing methodology, useful in the quantitative prediction of binding affinity: current methods for the in silico identification of T-cell epitopes (which form the basis of many vaccines, diagnostics, and reagents) rely on the accurate computational prediction of peptide-MHC affinity. We have reviewed various human and mouse class I and class II allele models. Studied alleles comprise HLA-A*0101, HLA-A*0201, HLA-A*0202, HLA-A*0203, HLA-A*0206, HLA-A*0301, HLA-A*1101, HLA-A*3101, HLA-A*6801, HLA-A*6802, HLA-B*3501, H2-K(k), H2-K(b), H2-D(b) HLA-DRB1*0101, HLA-DRB1*0401, HLA-DRB1*0701, I-A(b), I-A(d), I-A(k), I-A(S), I-E(d), and I-E(k). In this chapter we show a step-by-step guide into predicting the reliability and the resulting models to represent an advance on existing methods. The peptides used in this study are available from the AntiJen database (http://www.jenner.ac.uk/AntiJen). The PLS method

  19. Mean-Square Convergence of Drift-Implicit One-Step Methods for Neutral Stochastic Delay Differential Equations with Jump Diffusion

    Directory of Open Access Journals (Sweden)

    Lin Hu

    2011-01-01

    Full Text Available A class of drift-implicit one-step schemes are proposed for the neutral stochastic delay differential equations (NSDDEs driven by Poisson processes. A general framework for mean-square convergence of the methods is provided. It is shown that under certain conditions global error estimates for a method can be inferred from estimates on its local error. The applicability of the mean-square convergence theory is illustrated by the stochastic θ-methods and the balanced implicit methods. It is derived from Theorem 3.1 that the order of the mean-square convergence of both of them for NSDDEs with jumps is 1/2. Numerical experiments illustrate the theoretical results. It is worth noting that the results of mean-square convergence of the stochastic θ-methods and the balanced implicit methods are also new.

  20. A two-step leaching method designed based on chemical fraction distribution of the heavy metals for selective leaching of Cd, Zn, Cu, and Pb from metallurgical sludge.

    Science.gov (United States)

    Wang, Fen; Yu, Junxia; Xiong, Wanli; Xu, Yuanlai; Chi, Ru-An

    2018-01-01

    For selective leaching and highly effective recovery of heavy metals from a metallurgical sludge, a two-step leaching method was designed based on the distribution analysis of the chemical fractions of the loaded heavy metal. Hydrochloric acid (HCl) was used as a leaching agent in the first step to leach the relatively labile heavy metals and then ethylenediamine tetraacetic acid (EDTA) was applied to leach the residual metals according to their different fractional distribution. Using the two-step leaching method, 82.89% of Cd, 55.73% of Zn, 10.85% of Cu, and 0.25% of Pb were leached in the first step by 0.7 M HCl at a contact time of 240 min, and the leaching efficiencies for Cd, Zn, Cu, and Pb were elevated up to 99.76, 91.41, 71.85, and 94.06%, by subsequent treatment with 0.2 M EDTA at 480 min, respectively. Furthermore, HCl leaching induced fractional redistribution, which might increase the mobility of the remaining metals and then facilitate the following metal removal by EDTA. The facilitation was further confirmed by the comparison to the one-step leaching method with single HCl or single EDTA, respectively. These results suggested that the designed two-step leaching method by HCl and EDTA could be used for selective leaching and effective recovery of heavy metals from the metallurgical sludge or heavy metal-contaminated solid media.

  1. Improving Genetic Evaluation of Litter Size Using a Single-step Model

    DEFF Research Database (Denmark)

    Guo, Xiangyu; Christensen, Ole Fredslund; Ostersen, Tage

    A recently developed single-step method allows genetic evaluation based on information from phenotypes, pedigree and markers simultaneously. This paper compared reliabilities of predicted breeding values obtained from single-step method and the traditional pedigree-based method for two litter size...... traits, total number of piglets born (TNB), and litter size at five days after birth (Ls 5) in Danish Landrace and Yorkshire pigs. The results showed that the single-step method combining phenotypic and genotypic information provided more accurate predictions than the pedigree-based method, not only...

  2. Cumulative Mass and NIOSH Variable Lifting Index Method for Risk Assessment: Possible Relations.

    Science.gov (United States)

    Stucchi, Giulia; Battevi, Natale; Pandolfi, Monica; Galinotti, Luca; Iodice, Simona; Favero, Chiara

    2018-02-01

    Objective The aim of this study was to explore whether the Variable Lifting Index (VLI) can be corrected for cumulative mass and thus test its efficacy in predicting the risk of low-back pain (LBP). Background A validation study of the VLI method was published in this journal reporting promising results. Although several studies highlighted a positive correlation between cumulative load and LBP, cumulative mass has never been considered in any of the studies investigating the relationship between manual material handling and LBP. Method Both VLI and cumulative mass were calculated for 2,374 exposed subjects using a systematic approach. Due to high variability of cumulative mass values, a stratification within VLI categories was employed. Dummy variables (1-4) were assigned to each class and used as a multiplier factor for the VLI, resulting in a new index (VLI_CMM). Data on LBP were collected by occupational physicians at the study sites. Logistic regression was used to estimate the risk of acute LBP within levels of risk exposure when compared with a control group formed by 1,028 unexposed subjects. Results Data showed greatly variable values of cumulative mass across all VLI classes. The potential effect of cumulative mass on damage emerged as not significant ( p value = .6526). Conclusion When comparing VLI_CMM with raw VLI, the former failed to prove itself as a better predictor of LBP risk. Application To recognize cumulative mass as a modifier, especially for lumbar degenerative spine diseases, authors of future studies should investigate potential association between the VLI and other damage variables.

  3. The 'PROCESO' index: a new methodology for the evaluation of operational safety in the chemical industry

    International Nuclear Information System (INIS)

    Marono, M.; Pena, J.A.; Santamaria, J.

    2006-01-01

    The acknowledgement of industrial installations as complex systems in the early 1980s outstands as a milestone in the path to operational safety. Process plants are social-technical complex systems of a dynamic nature, whose properties depend not only on their components, but also on the inter-relations among them. A comprehensive assessment of operational safety requires a systemic approach, i.e. an integrated framework that includes all the relevant factors influencing safety. Risk analysis methodologies and safety management systems head the list of methods that point in this direction, but they normally require important plant resources. As a consequence, their use is frequently restricted to especially dangerous processes often driven by compliance with legal requirements. In this work a new safety index for the chemical industry, termed the 'Proceso' Index (standing for the Spanish terms for PROCedure for the Evaluation of Operational Safety), has been developed. PROCESO is based on the principles of systems theory, has a tree-like structure and considers 25 areas to guide the review of plant safety. The method uses indicators whose respective weight values have been obtained via an expert judgement technique. This paper describes the steps followed to develop this new Operational Safety Index, explains its structure and illustrates its application to process plants

  4. A novel technique to solve nonlinear higher-index Hessenberg differential-algebraic equations by Adomian decomposition method.

    Science.gov (United States)

    Benhammouda, Brahim

    2016-01-01

    Since 1980, the Adomian decomposition method (ADM) has been extensively used as a simple powerful tool that applies directly to solve different kinds of nonlinear equations including functional, differential, integro-differential and algebraic equations. However, for differential-algebraic equations (DAEs) the ADM is applied only in four earlier works. There, the DAEs are first pre-processed by some transformations like index reductions before applying the ADM. The drawback of such transformations is that they can involve complex algorithms, can be computationally expensive and may lead to non-physical solutions. The purpose of this paper is to propose a novel technique that applies the ADM directly to solve a class of nonlinear higher-index Hessenberg DAEs systems efficiently. The main advantage of this technique is that; firstly it avoids complex transformations like index reductions and leads to a simple general algorithm. Secondly, it reduces the computational work by solving only linear algebraic systems with a constant coefficient matrix at each iteration, except for the first iteration where the algebraic system is nonlinear (if the DAE is nonlinear with respect to the algebraic variable). To demonstrate the effectiveness of the proposed technique, we apply it to a nonlinear index-three Hessenberg DAEs system with nonlinear algebraic constraints. This technique is straightforward and can be programmed in Maple or Mathematica to simulate real application problems.

  5. One-step production of biodiesel from Nannochloropsis sp. on solid base Mg-Zr catalyst

    International Nuclear Information System (INIS)

    Li, Yuesong; Lian, Shuang; Tong, Dongmei; Song, Ruili; Yang, Wenyan; Fan, Yong; Qing, Renwei; Hu, Changwei

    2011-01-01

    Nannochloropsis sp., one kind of green microalgae cultivated autotrophically and axenically in laboratory, is used as raw material to produce biodiesel by one-step method in an amended reactor. The effects of several reaction parameters on transesterification over Mg-Zr solid base catalyst were investigated through both conventional method and one-step method. One-step method could give a higher yield of methyl ester than conventional two-step method, which demonstrates that the present one-step method is suitable for biodiesel production from the microalgae Nannochloropsis sp. Moreover, the present one-step method realizes the convenient in situ separation of catalyst from microalgae residue which can be easily used consequently, reducing the procedure units as well as the overall costs.

  6. Fast Measurement of Methanol Concentration in Ionic Liquids by Potential Step Method

    Directory of Open Access Journals (Sweden)

    Michael L. Hainstock

    2015-01-01

    Full Text Available The development of direct methanol fuel cells required the attention to the electrolyte. A good electrolyte should not only be ionic conductive but also be crossover resistant. Ionic liquids could be a promising electrolyte for fuel cells. Monitoring methanol was critical in several locations in a direct methanol fuel cell. Conductivity could be used to monitor the methanol content in ionic liquids. The conductivity of 1-butyl-3-methylimidazolium tetrafluoroborate had a linear relationship with the methanol concentration. However, the conductivity was significantly affected by the moisture or water content in the ionic liquid. On the contrary, potential step could be used in sensing methanol in ionic liquids. This method was not affected by the water content. The sampling current at a properly selected sampling time was proportional to the concentration of methanol in 1-butyl-3-methylimidazolium tetrafluoroborate. The linearity still stood even when there was 2.4 M water present in the ionic liquid.

  7. Development of resilience evaluation method for nuclear power plants. Part 3. Study of evaluation method and applicability of resilience index

    International Nuclear Information System (INIS)

    Suzuki, Masaaki; Demachi, Kazuyuki; Miyano, Hiroshi

    2017-01-01

    We have developed a new index, called the resilience index, that evaluates the dynamic stability of the system safety of a nuclear power plant during a severe accident by considering the ability to recover system safety functions that have become lost in the situation. In this paper, a detailed evaluation procedure for the resilience index is described. The system safety of a pressurized water reactor plant during a severe accident is then assessed according to the resilience index in order to discuss the applicability of the index. We find that the resilience index successfully represents management capability and, therefore, the resilience capability of a nuclear power plant. (author)

  8. Development of resilience evaluation method for nuclear power plants. Part 3. Study on evaluation method and applicability of resilience index

    International Nuclear Information System (INIS)

    Suzuki, Masaaki; Demachi, Kazuyuki; Murakami, Kenta

    2016-01-01

    We have developed a new index, called the resilience index, that evaluates the dynamic stability of the system safety of a nuclear power plant during a severe accident by considering the ability to recover system safety functions that have become lost in the situation. In this paper, a detailed evaluation procedure for the resilience index is described. The system safety of a PWR plant during a severe accident is then assessed according to the resilience index in order to discuss the applicability of the index. We find that the resilience index successfully represents management capability and, therefore, the resilience capability of a nuclear power plant. (author)

  9. Validation of the Abdominal Pain Index using a revised scoring method.

    Science.gov (United States)

    Laird, Kelsey T; Sherman, Amanda L; Smith, Craig A; Walker, Lynn S

    2015-06-01

    Evaluate the psychometric properties of child- and parent-report versions of the four-item Abdominal Pain Index (API) in children with functional abdominal pain (FAP) and healthy controls, using a revised scoring method that facilitates comparisons of scores across samples and time. Pediatric patients aged 8-18 years with FAP and controls completed the API at baseline (N = 1,967); a subset of their parents (N = 290) completed the API regarding the child's pain. Subsets of patients completed follow-up assessments at 2 weeks (N = 231), 3 months (N = 330), and 6 months (N = 107). Subsets of both patients (N = 389) and healthy controls (N = 172) completed a long-term follow-up assessment (mean age at follow-up = 20.21 years, SD = 3.75). The API demonstrated good concurrent, discriminant, and construct validity, as well as good internal consistency. We conclude that the API, using the revised scoring method, is a useful, reliable, and valid measure of abdominal pain severity. © The Author 2015. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Antenna characteristics and air-ground interface deembedding methods for stepped-frequency ground-penetrating radar measurements

    DEFF Research Database (Denmark)

    Karlsen, Brian; Larsen, Jan; Jakobsen, Kaj Bjarne

    2000-01-01

    The result from field-tests using a Stepped-Frequency Ground Penetrating Radar (SF-GPR) and promising antenna and air-ground deembedding methods for a SF-GPR is presented. A monostatic S-band rectangular waveguide antenna was used in the field-tests. The advantages of the SF-GPR, e.g., amplitude...... and phase information in the SF-GPR signal, is used to deembed the characteristics of the antenna. We propose a new air-to-ground interface deembedding technique based on Principal Component Analysis which enables enhancement of the SF-GPR signal from buried objects, e.g., anti-personal landmines...

  11. Feasibility of the Medial Temporal lobe Atrophy index (MTAi and derived methods for measuring atrophy of the medial temporal lobe

    Directory of Open Access Journals (Sweden)

    Francisco eConejo Bayón

    2014-11-01

    Full Text Available Introduction: the Medial Temporal-lobe Atrophy index (MTAi, 2D-Medial Temporal Atrophy (2D-MTA, yearly rate of MTA (yrRMTA and yearly rate of relative MTA (yrRMTA are simple protocols for measuring the relative extent of atrophy in the MTL in relation to the global brain atrophy. Albeit preliminary studies showed interest of these methods in the diagnosis of AD, FTLD and correlation with cognitive impairment in PD, formal feasibility and validity studies remained pending. As a first step, we aimed to assess the feasibility. Mainly, we aimed to assess the reproducibility of measuring the areas needed to compute these indices. We also aimed to assess the efforts needed to start using these methods correctly. Methods: a series of 290 1.5T-MRI studies from 230 subjects ranging 65-85 years old who had been studied for cognitive impairment were used in this study. Six inexperienced tracers (IT plus one experienced tracer (ET traced the three areas needed to compute the indices. Finally, tracers underwent a short survey on their experience learning to compute the MTAi and experience of usage, including items relative to training time needed to understand and apply the MTAi, time to perform a study after training and overall satisfaction. Results: learning to trace the areas needed to compute the MTAi and derived methods is quick and easy. Results indicate very good intrarater ICC for the MTAi, good intrarater ICC for the 2D-MTA, yrMTA and yrRMTA and also good interrater ICC for the MTAi, 2D-MTA, yrMTA and yrRMTA.Conclusion: our data support that MTAi and derived methods (2D-MTA, yrMTA and yrRTMA have good to very good intrarater and interrater reproducibility and may be easily implemented in clinical practice even if new users have no experience tracing the area of regions of interest.

  12. Combining Different Conceptual Change Methods within Four-Step Constructivist Teaching Model: A Sample Teaching of Series and Parallel Circuits

    Science.gov (United States)

    Ipek, Hava; Calik, Muammer

    2008-01-01

    Based on students' alternative conceptions of the topics "electric circuits", "electric charge flows within an electric circuit", "how the brightness of bulbs and the resistance changes in series and parallel circuits", the current study aims to present a combination of different conceptual change methods within a four-step constructivist teaching…

  13. A surface refractive index scanning system and method

    DEFF Research Database (Denmark)

    2015-01-01

    The invention relates to a surface refractive index scanning system for characterization of a sample. The system comprises a grating device for holding or receiving the sample, the device comprising at least a first grating region having a first grating width along a transverse direction, and a s......The invention relates to a surface refractive index scanning system for characterization of a sample. The system comprises a grating device for holding or receiving the sample, the device comprising at least a first grating region having a first grating width along a transverse direction...... a grating period Λ2 in the longitudinal direction, where the longitudinal direction is orthogonal to the transverse direction. A grating period spacing ΔΛ = Λ1 - Λ2 is finite. Further, the first and second grating periods are chosen to provide optical resonances for light respectively in a first...... wavelength band and a second wavelength band, light is being emitted, transmitted, or reflected in an out-of-plane direction, wherein the first wavelength band and the second wavelength band are at least partially non-overlapping in wavelength. The system further comprises a light source for illuminating...

  14. Steps and dislocations in cubic lyotropic crystals

    International Nuclear Information System (INIS)

    Leroy, S; Pieranski, P

    2006-01-01

    It has been shown recently that lyotropic systems are convenient for studies of faceting, growth or anisotropic surface melting of crystals. All these phenomena imply the active contribution of surface steps and bulk dislocations. We show here that steps can be observed in situ and in real time by means of a new method combining hygroscopy with phase contrast. First results raise interesting issues about the consequences of bicontinuous topology on the structure and dynamical behaviour of steps and dislocations

  15. A Two-Step Approach to Uncertainty Quantification of Core Simulators

    Directory of Open Access Journals (Sweden)

    Artem Yankov

    2012-01-01

    Full Text Available For the multiple sources of error introduced into the standard computational regime for simulating reactor cores, rigorous uncertainty analysis methods are available primarily to quantify the effects of cross section uncertainties. Two methods for propagating cross section uncertainties through core simulators are the XSUSA statistical approach and the “two-step” method. The XSUSA approach, which is based on the SUSA code package, is fundamentally a stochastic sampling method. Alternatively, the two-step method utilizes generalized perturbation theory in the first step and stochastic sampling in the second step. The consistency of these two methods in quantifying uncertainties in the multiplication factor and in the core power distribution was examined in the framework of phase I-3 of the OECD Uncertainty Analysis in Modeling benchmark. With the Three Mile Island Unit 1 core as a base model for analysis, the XSUSA and two-step methods were applied with certain limitations, and the results were compared to those produced by other stochastic sampling-based codes. Based on the uncertainty analysis results, conclusions were drawn as to the method that is currently more viable for computing uncertainties in burnup and transient calculations.

  16. Flux decay during thermonuclear X-ray bursts analysed with the dynamic power-law index method

    Science.gov (United States)

    Kuuttila, J.; Kajava, J. J. E.; Nättilä, J.; Motta, S. E.; Sánchez-Fernández, C.; Kuulkers, E.; Cumming, A.; Poutanen, J.

    2017-08-01

    The cooling of type-I X-ray bursts can be used to probe the nuclear burning conditions in neutron star envelopes. The flux decay of the bursts has been traditionally modelled with an exponential, even if theoretical considerations predict power-law-like decays. We have analysed a total of 540 type-I X-ray bursts from five low-mass X-ray binaries observed with the Rossi X-ray Timing Explorer. We grouped the bursts according to the source spectral state during which they were observed (hard or soft), flagging those bursts that showed signs of photospheric radius expansion (PRE). The decay phase of all the bursts were then fitted with a dynamic power-law index method. This method provides a new way of probing the chemical composition of the accreted material. Our results show that in the hydrogen-rich sources the power-law decay index is variable during the burst tails and that simple cooling models qualitatively describe the cooling of presumably helium-rich sources 4U 1728-34 and 3A 1820-303. The cooling in the hydrogen-rich sources 4U 1608-52, 4U 1636-536, and GS 1826-24, instead, is clearly different and depends on the spectral states and whether PRE occurred or not. Especially the hard state bursts behave differently than the models predict, exhibiting a peculiar rise in the cooling index at low burst fluxes, which suggests that the cooling in the tail is much faster than expected. Our results indicate that the drivers of the bursting behaviour are not only the accretion rate and chemical composition of the accreted material, but also the cooling that is somehow linked to the spectral states. The latter suggests that the properties of the burning layers deep in the neutron star envelope might be impacted differently depending on the spectral state.

  17. Can sedentary behavior be made more active? A randomized pilot study of TV commercial stepping versus walking

    Directory of Open Access Journals (Sweden)

    Steeves Jeremy A

    2012-08-01

    Full Text Available Abstract Background There is a growing problem of physical inactivity in America, and approximately a quarter of the population report being completely sedentary during their leisure time. In the U.S., TV viewing is the most common leisure-time activity. Stepping in place during TV commercials (TV Commercial Stepping could increase physical activity. The purpose of this study was to examine the feasibility of incorporating physical activity (PA into a traditionally sedentary activity, by comparing TV Commercial Stepping during 90 min/d of TV programming to traditional exercise (Walking. Methods A randomized controlled pilot study of the impact of 6 months of TV Commercial Stepping versus Walking 30 min/day in adults was conducted. 58 sedentary, overweight (body mass index 33.5 ± 4.8 kg/m2 adults (age 52.0 ± 8.6 y were randomly assigned to one of two 6-mo behavioral PA programs: 1 TV Commercial Stepping; or 2 Walking 30 min/day. To help facilitate behavior changes participants received 6 monthly phone calls, attended monthly meetings for the first 3 months, and received monthly newsletters for the last 3 months. Using intent-to-treat analysis, changes in daily steps, TV viewing, diet, body weight, waist and hip circumference, and percent fat were compared at baseline, 3, and 6 mo. Data were collected in 2010–2011, and analyzed in 2011. Results Of the 58 subjects, 47 (81% were retained for follow-up at the completion of the 6-mo program. From baseline to 6-mo, both groups significantly increased their daily steps [4611 ± 1553 steps/d vs. 7605 ± 2471 steps/d (TV Commercial Stepping; 4909 ± 1335 steps/d vs. 7865 ± 1939 steps/d (Walking; P  Conclusions Participants in both the TV Commercial Stepping and Walking groups had favorable changes in daily steps, TV viewing, diet, and anthropometrics. PA can be performed while viewing TV commercials and this may be a feasible alternative to traditional approaches for

  18. A NEW METHOD FOR 3D SHAPE INDEXING AND RETRIEVAL IN LARGE DATABASE BY USING THE LEVEL CUT

    OpenAIRE

    M. Elkhal; A. Lakehal; K. Satori

    2014-01-01

    In this study, we propose a new method for indexing and retrieval of 3D models in large databases based on binary images extracted from the 3D object called “level cut” LC. These cuts are obtained by the intersection of the set of the plans with the 3D object. A set of equidistant parallel plans generates by the intersection with the 3D object a set of cuts that used to indexing the 3D model. We are based on these cuts to describe the 3D object by using the vectors descriptors bas...

  19. KPG Index versus OPG Measurements: A Comparison between 3D and 2D Methods in Predicting Treatment Duration and Difficulty Level for Patients with Impacted Maxillary Canines

    Directory of Open Access Journals (Sweden)

    Domenico Dalessandri

    2014-01-01

    Full Text Available Aim. The aim of this study was to test the agreement between orthopantomography (OPG based 2D measurements and the KPG index, a new index based on 3D Cone Beam Computed Tomography (CBCT images, in predicting orthodontic treatment duration and difficulty level of impacted maxillary canines. Materials and Methods. OPG and CBCT images of 105 impacted canines were independently scored by three orthodontists at t0 and after 1 month (t1, using the KPG index and the following 2D methods: distance from cusp tip and occlusal plane, cusp tip position in relation to the lateral incisor, and canine inclination. Pearson’s coefficients were used to evaluate the degree of agreement and the χ2 with Yates correction test was used to assess the independence between them. Results. Inter- and intrarater reliability were higher with KPG compared to 2D methods. Pearson’s coefficients showed a statistically significant association between all the indexes, while the χ2 with Yates correction test resulted in a statistically significant rejection of independency only for one 2D index. Conclusions. 2D indexes for predicting impacted maxillary canines treatment duration and difficulty sometimes are discordant; a 3D index like the KPG index could be useful in solving these conflicts.

  20. Video-Recorded Validation of Wearable Step Counters under Free-living Conditions.

    Science.gov (United States)

    Toth, Lindsay P; Park, Susan; Springer, Cary M; Feyerabend, McKenzie D; Steeves, Jeremy A; Bassett, David R

    2018-06-01

    The purpose of this study was to determine the accuracy of 14-step counting methods under free-living conditions. Twelve adults (mean ± SD age, 35 ± 13 yr) wore a chest harness that held a GoPro camera pointed down at the feet during all waking hours for 1 d. The GoPro continuously recorded video of all steps taken throughout the day. Simultaneously, participants wore two StepWatch (SW) devices on each ankle (all programmed with different settings), one activPAL on each thigh, four devices at the waist (Fitbit Zip, Yamax Digi-Walker SW-200, New Lifestyles NL-2000, and ActiGraph GT9X (AG)), and two devices on the dominant and nondominant wrists (Fitbit Charge and AG). The GoPro videos were downloaded to a computer and researchers counted steps using a hand tally device, which served as the criterion method. The SW devices recorded between 95.3% and 102.8% of actual steps taken throughout the day (P > 0.05). Eleven step counting methods estimated less than 100% of actual steps; Fitbit Zip, Yamax Digi-Walker SW-200, and AG with the moving average vector magnitude algorithm on both wrists recorded 71% to 91% of steps (P > 0.05), whereas the activPAL, New Lifestyles NL-2000, and AG (without low-frequency extension (no-LFE), moving average vector magnitude) worn on the hip, and Fitbit Charge recorded 69% to 84% of steps (P 0.05), whereas the AG (LFE) on both wrists and the hip recorded 128% to 220% of steps (P < 0.05). Across all waking hours of 1 d, step counts differ between devices. The SW, regardless of settings, was the most accurate method of counting steps.

  1. Multi-Level Bitmap Indexes for Flash Memory Storage

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Kesheng; Madduri, Kamesh; Canon, Shane

    2010-07-23

    Due to their low access latency, high read speed, and power-efficient operation, flash memory storage devices are rapidly emerging as an attractive alternative to traditional magnetic storage devices. However, tests show that the most efficient indexing methods are not able to take advantage of the flash memory storage devices. In this paper, we present a set of multi-level bitmap indexes that can effectively take advantage of flash storage devices. These indexing methods use coarsely binned indexes to answer queries approximately, and then use finely binned indexes to refine the answers. Our new methods read significantly lower volumes of data at the expense of an increased disk access count, thus taking full advantage of the improved read speed and low access latency of flash devices. To demonstrate the advantage of these new indexes, we measure their performance on a number of storage systems using a standard data warehousing benchmark called the Set Query Benchmark. We observe that multi-level strategies on flash drives are up to 3 times faster than traditional indexing strategies on magnetic disk drives.

  2. A method for matching the refractive index and kinematic viscosity of a blood analog for flow visualization in hydraulic cardiovascular models.

    Science.gov (United States)

    Nguyen, T T; Biadillah, Y; Mongrain, R; Brunette, J; Tardif, J C; Bertrand, O F

    2004-08-01

    In this work, we propose a simple method to simultaneously match the refractive index and kinematic viscosity of a circulating blood analog in hydraulic models for optical flow measurement techniques (PIV, PMFV, LDA, and LIF). The method is based on the determination of the volumetric proportions and temperature at which two transparent miscible liquids should be mixed to reproduce the targeted fluid characteristics. The temperature dependence models are a linear relation for the refractive index and an Arrhenius relation for the dynamic viscosity of each liquid. Then the dynamic viscosity of the mixture is represented with a Grunberg-Nissan model of type 1. Experimental tests for acrylic and blood viscosity were found to be in very good agreement with the targeted values (measured refractive index of 1.486 and kinematic viscosity of 3.454 milli-m2/s with targeted values of 1.47 and 3.300 milli-m2/s).

  3. Indexing from thesauri to the semantic web

    CERN Document Server

    de Keyser, Piet

    2012-01-01

    Indexing consists of both novel and more traditional techniques. Cutting-edge indexing techniques, such as automatic indexing, ontologies, and topic maps, were developed independently of older techniques such as thesauri, but it is now recognized that these older methods also hold expertise. Indexing describes various traditional and novel indexing techniques, giving information professionals and students of library and information sciences a broad and comprehensible introduction to indexing. This title consists of twelve chapters: an Introduction to subject readings and theasauri; Automatic i

  4. Synthesis and characterization of ZnO/Cu2O core–shell nanowires grown by two-step electrodeposition method

    International Nuclear Information System (INIS)

    Messaoudi, O.; Makhlouf, H.; Souissi, A.; Ben assaker, I.; Amiri, G.; Bardaoui, A.; Oueslati, M.; Bechelany, M.; Chtourou, R.

    2015-01-01

    Highlights: • ZnO/Cu 2 O core/shell nanowires have been grown by two-step electrodeposition method. • SEM confirmed the homogenous distribution of Cu 2 O on the deposited nanowires. • The X-ray diffraction demonstrated that the films were pure. • Optical transmissions measurements reveal an additional contribution at about 1.7 eV. • The ZnO/Cu 2 O structure is expected to have an advantage in photovoltaic application. - Abstract: ZnO/Cu 2 O core/shell nanowires have been grown by two-step electrodeposition method on ITO-coated glass substrates. The sample's morphology was explored by means of scanning electron microscopy (SEM). SEM images confirm the homogeneity of the nanowires and the presence of Cu 2 O shell on ZnO core. X-ray diffraction and Raman scattering measurements were used to investigate the purity and the crystallinity of the samples. Optical transmission measurements reveal an additional contribution at about 1.7 eV attributed to the type-II interfacial transition witch confirms the advantage of using the ZnO/Cu 2 O structure in photovoltaic application

  5. Robust indexing for automatic data collection

    International Nuclear Information System (INIS)

    Sauter, Nicholas K.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.

    2003-01-01

    We present improved methods for indexing diffraction patterns from macromolecular crystals. The novel procedures include a more robust way to verify the position of the incident X-ray beam on the detector, an algorithm to verify that the deduced lattice basis is consistent with the observations, and an alternative approach to identify the metric symmetry of the lattice. These methods help to correct failures commonly experienced during indexing, and increase the overall success rate of the process. Rapid indexing, without the need for visual inspection, will play an important role as beamlines at synchrotron sources prepare for high-throughput automation

  6. INDEXING AND INDEX FUNDS

    Directory of Open Access Journals (Sweden)

    HAKAN SARITAŞ

    2013-06-01

    Full Text Available Proponents of the efficient market hypothesis believe that active portfolio management is largely wasted effort and unlikely to justify the expenses incurred. Therefore, they advocate a passive investment strategy that makes no attempt to outsmart the market. One common strategy for passive management is indexing where a fund is designed to replicate the performance of a broad-based index of stocks and bonds. Traditionally, indexing was used by institutional investors, but today, the use of index funds proliferated among individual investors. Over the years, both international and domestic index funds have disproportionately outperformed the market more than the actively managed funds have.

  7. [Cross-cultural adaptation of the Quality of Life Index Spinal Cord Injury - Version III].

    Science.gov (United States)

    Reis, Priscila Alencar Mendes; Carvalho, Zuila Maria de Figueiredo; Tirado Darder, Juan José; Oriá, Mônica Oliveira Batista; Studart, Rita Mônica Borges; Maniva, Samia Jardelle Costa de Freitas

    2015-06-01

    To translate and culturally adapt to Portuguese the Ferrans and Powers Quality of Life Index Spinal Cord Injury - Version III and characterize the sample in relation to sociodemographic and clinical aspects. A methodological study with view to cross-cultural adaptation, following the particular steps of this method: initial translation, translation synthesis, back-translation (translation back to the original language), review by a committee of judges and pretest of the final version. The pretest was carried out with 30 patients with spinal cord injury. An index of 74 items divided into two parts (satisfaction/importance) was obtained. The criteria of semantic equivalence were evaluated as very adequate translation, higher than 87%, and vocabulary and were grammar higher than 86%. Idiomatic equivalence was higher than 74%, experimental greater than 78% and conceptual was greater than 70%. After cross-cultural adaptation, the instrument proved semantic, idiomatic, experimental and conceptual adequacy, in addition to helping the evaluation of the quality of life of people with spinal cord injury.

  8. Performance of Islamic Stocks Index: Comparative Studies Between Indonesia and Malaysia

    Directory of Open Access Journals (Sweden)

    Tulasmi Tulasmi

    2016-06-01

    Full Text Available The aim of this research is to compare the Islamic stocks index performance between Malaysia and Indonesia using Sharpe method, Treynor method, and Jensen method. The result show that the Islamic stocks index performance in Indonesia –measured by Jakarta Islamic Index- is better than Malaysia if using Treynor and Jensen methods. Otherwise, using the Sharpe method show that Islamic stock index in Malaysia is better than Islamic stocks index in Indonesia. The implication from this result is the investor with enough funds recommended to invest in Indonesia, but the small investor can do the investment to Islamic stocks index in Malaysia.DOI:  10.15408/sjie.v5i1.3127 

  9. Effects of Conjugate Gradient Methods and Step-Length Formulas on the Multiscale Full Waveform Inversion in Time Domain: Numerical Experiments

    Science.gov (United States)

    Liu, Youshan; Teng, Jiwen; Xu, Tao; Badal, José; Liu, Qinya; Zhou, Bing

    2017-05-01

    We carry out full waveform inversion (FWI) in time domain based on an alternative frequency-band selection strategy that allows us to implement the method with success. This strategy aims at decomposing the seismic data within partially overlapped frequency intervals by carrying out a concatenated treatment of the wavelet to largely avoid redundant frequency information to adapt to wavelength or wavenumber coverage. A pertinent numerical test proves the effectiveness of this strategy. Based on this strategy, we comparatively analyze the effects of update parameters for the nonlinear conjugate gradient (CG) method and step-length formulas on the multiscale FWI through several numerical tests. The investigations of up to eight versions of the nonlinear CG method with and without Gaussian white noise make clear that the HS (Hestenes and Stiefel in J Res Natl Bur Stand Sect 5:409-436, 1952), CD (Fletcher in Practical methods of optimization vol. 1: unconstrained optimization, Wiley, New York, 1987), and PRP (Polak and Ribière in Revue Francaise Informat Recherche Opertionelle, 3e Année 16:35-43, 1969; Polyak in USSR Comput Math Math Phys 9:94-112, 1969) versions are more efficient among the eight versions, while the DY (Dai and Yuan in SIAM J Optim 10:177-182, 1999) version always yields inaccurate result, because it overestimates the deeper parts of the model. The application of FWI algorithms using distinct step-length formulas, such as the direct method ( Direct), the parabolic search method ( Search), and the two-point quadratic interpolation method ( Interp), proves that the Interp is more efficient for noise-free data, while the Direct is more efficient for Gaussian white noise data. In contrast, the Search is less efficient because of its slow convergence. In general, the three step-length formulas are robust or partly insensitive to Gaussian white noise and the complexity of the model. When the initial velocity model deviates far from the real model or the

  10. Cross-cultural adaptation of instruments assessing breastfeeding determinants: a multi-step approach

    Science.gov (United States)

    2014-01-01

    Background Cross-cultural adaptation is a necessary process to effectively use existing instruments in other cultural and language settings. The process of cross-culturally adapting, including translation, of existing instruments is considered a critical set to establishing a meaningful instrument for use in another setting. Using a multi-step approach is considered best practice in achieving cultural and semantic equivalence of the adapted version. We aimed to ensure the content validity of our instruments in the cultural context of KwaZulu-Natal, South Africa. Methods The Iowa Infant Feeding Attitudes Scale, Breastfeeding Self-Efficacy Scale-Short Form and additional items comprise our consolidated instrument, which was cross-culturally adapted utilizing a multi-step approach during August 2012. Cross-cultural adaptation was achieved through steps to maintain content validity and attain semantic equivalence in the target version. Specifically, Lynn’s recommendation to apply an item-level content validity index score was followed. The revised instrument was translated and back-translated. To ensure semantic equivalence, Brislin’s back-translation approach was utilized followed by the committee review to address any discrepancies that emerged from translation. Results Our consolidated instrument was adapted to be culturally relevant and translated to yield more reliable and valid results for use in our larger research study to measure infant feeding determinants effectively in our target cultural context. Conclusions Undertaking rigorous steps to effectively ensure cross-cultural adaptation increases our confidence that the conclusions we make based on our self-report instrument(s) will be stronger. In this way, our aim to achieve strong cross-cultural adaptation of our consolidated instruments was achieved while also providing a clear framework for other researchers choosing to utilize existing instruments for work in other cultural, geographic and population

  11. Assessment of Postural Load Index Using LUBA Method and the Prevalence of Musculoskeletal Disorders in Dentists

    Directory of Open Access Journals (Sweden)

    Zeinab Baroonyzade

    2014-06-01

    Full Text Available Background & Objectives : High prevalence of musculoskeletal pain in dentistry represents the importance of investigation of working conditions in this profession to reduce musculoskeletal disorders.The purpose of this study was to determine the postural load on the upper limb postural using macro LUBA technique and the prevalence of musculoskeletal disorders. Methods: This study was conducted on 30 post graduate dental students of Hamadan University of Medical Sciences . LUBA technique was used to evaluate the postural load. The Nordic questionnaire was used to assess the prevalence of musculoskeletal disorders . The results were analyzed using SPSS version 16 . Results: The prevalence of musculoskeletal disorders was as follows neck( 63.3%, back ( 43.3%, back ( 30%, knee ( 20%, shoulder( 13%, wrist ( 10%, legs (10 %, elbows( 6.7% and thigh( 0%. The maximum postural load index was 23 for women and 21for men. In total, 50 % of dentists were in group 3 , 33 % of dentists in group 4 and 16.7 % in group 2 of the corrective measures . There was no significant association b etween demographic variables and presence of musculoskeletal disorders . Besides, there was no significant association between the presence of pain in upper limbs and the postural load index (Pvalue > 0.05. Conclusions: This study showed high levels of p ostural load index and musculoskeletal disorders among dental students of Hamadan University of Medical Sciences. High levels of p ostural load index indicate a high level of risk, which requires immediate corrective action and intervention.

  12. Stabilization of a three-dimensional limit cycle walking model through step-to-step ankle control.

    Science.gov (United States)

    Kim, Myunghee; Collins, Steven H

    2013-06-01

    Unilateral, below-knee amputation is associated with an increased risk of falls, which may be partially related to a loss of active ankle control. If ankle control can contribute significantly to maintaining balance, even in the presence of active foot placement, this might provide an opportunity to improve balance using robotic ankle-foot prostheses. We investigated ankle- and hip-based walking stabilization methods in a three-dimensional model of human gait that included ankle plantarflexion, ankle inversion-eversion, hip flexion-extension, and hip ad/abduction. We generated discrete feedback control laws (linear quadratic regulators) that altered nominal actuation parameters once per step. We used ankle push-off, lateral ankle stiffness and damping, fore-aft foot placement, lateral foot placement, or all of these as control inputs. We modeled environmental disturbances as random, bounded, unexpected changes in floor height, and defined balance performance as the maximum allowable disturbance value for which the model walked 500 steps without falling. Nominal walking motions were unstable, but were stabilized by all of the step-to-step control laws we tested. Surprisingly, step-by-step modulation of ankle push-off alone led to better balance performance (3.2% leg length) than lateral foot placement (1.2% leg length) for these control laws. These results suggest that appropriate control of robotic ankle-foot prosthesis push-off could make balancing during walking easier for individuals with amputation.

  13. Storybridging : Four steps for constructing effective health narratives

    NARCIS (Netherlands)

    Boeijinga, A.; Hoeken, Hans; Sanders, José

    2017-01-01

    Objective: To develop a practical step-by-step approach to constructing narrative health interventions in response to the mixed results and wide diversity of narratives used in health-related narrative persuasion research. Method: Development work was guided by essential narrative characteristics as

  14. Efficient formalism for treating tapered structures using the Fourier modal method

    DEFF Research Database (Denmark)

    Østerkryger, Andreas Dyhl; Gregersen, Niels

    2016-01-01

    We investigate the development of the mode occupations in tapered structures using the Fourier modal method. In order to use the Fourier modal method, tapered structures are divided into layers of uniform refractive index in the propagation direction and the optical modes are found within each...... layer. This is not very efficient and in this proceeding we take the first steps towards a more efficient formalism for treating tapered structures using the Fourier modal method. We show that the coupling coefficients through the structure are slowly varying and that only the first few modes...

  15. Two-step sintering of ultrafine-grained barium cerate proton conducting ceramics

    International Nuclear Information System (INIS)

    Wang, Siwei; Zhang, Lei; Zhang, Lingling; Brinkman, Kyle; Chen, Fanglin

    2013-01-01

    Ultra-fine grained dense BaZr 0.1 Ce 0.7 Y 0.1 Yb 0.1 O 3−δ (BZCYYb) ceramics have been successfully prepared via a two-step sintering method. Co-precipitation method has been adopted to prepare nano-sized BZCYYb precursors with an average particle size of 30 nm. By controlling the sintering profile, an average grain size of 184 nm was obtained for dense BZCYYb ceramics via the two-step sintering method, compared to 445 nm for the conventional sintered samples. The two-step sintered BZCYYb samples showed less impurity and an enhanced electrical conductivity compared with the conventional sintered ones. Further, the two-step sintering method was applied to fabricate anode supported solid oxide fuel cells (SOFCs) using BZCYYb as the electrolyte, resulting in dense ultrafine-grained electrolyte membranes and porous anode substrates with fine particles. Due to the reduced ohmic as well as polarization resistances, the maximum power output of the cells fabricated from the two-step sintering method reached 349 mW m −2 at 700 °C, significantly improved from 172 mW cm −2 for the conventional sintered cells, suggesting that two-step sintering method is very promising for optimizing the microstructure and thus enhancing the electrochemical performances for barium cerate based proton-conducting SOFCs.

  16. PREDICTING THE BOILING POINT OF PCDD/Fs BY THE QSPR METHOD BASED ON THE MOLECULAR DISTANCE-EDGE VECTOR INDEX

    Directory of Open Access Journals (Sweden)

    Long Jiao

    2015-05-01

    Full Text Available The quantitative structure property relationship (QSPR for the boiling point (Tb of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs was investigated. The molecular distance-edge vector (MDEV index was used as the structural descriptor. The quantitative relationship between the MDEV index and Tb was modeled by using multivariate linear regression (MLR and artificial neural network (ANN, respectively. Leave-one-out cross validation and external validation were carried out to assess the prediction performance of the models developed. For the MLR method, the prediction root mean square relative error (RMSRE of leave-one-out cross validation and external validation was 1.77 and 1.23, respectively. For the ANN method, the prediction RMSRE of leave-one-out cross validation and external validation was 1.65 and 1.16, respectively. A quantitative relationship between the MDEV index and Tb of PCDD/Fs was demonstrated. Both MLR and ANN are practicable for modeling this relationship. The MLR model and ANN model developed can be used to predict the Tb of PCDD/Fs. Thus, the Tb of each PCDD/F was predicted by the developed models.

  17. Retrieving Leaf Area Index (LAI) Using Remote Sensing: Theories, Methods and Sensors.

    Science.gov (United States)

    Zheng, Guang; Moskal, L Monika

    2009-01-01

    The ability to accurately and rapidly acquire leaf area index (LAI) is an indispensable component of process-based ecological research facilitating the understanding of gas-vegetation exchange phenomenon at an array of spatial scales from the leaf to the landscape. However, LAI is difficult to directly acquire for large spatial extents due to its time consuming and work intensive nature. Such efforts have been significantly improved by the emergence of optical and active remote sensing techniques. This paper reviews the definitions and theories of LAI measurement with respect to direct and indirect methods. Then, the methodologies for LAI retrieval with regard to the characteristics of a range of remotely sensed datasets are discussed. Remote sensing indirect methods are subdivided into two categories of passive and active remote sensing, which are further categorized as terrestrial, aerial and satellite-born platforms. Due to a wide variety in spatial resolution of remotely sensed data and the requirements of ecological modeling, the scaling issue of LAI is discussed and special consideration is given to extrapolation of measurement to landscape and regional levels.

  18. Arsenic fractionation in agricultural soil using an automated three-step sequential extraction method coupled to hydride generation-atomic fluorescence spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Rosas-Castor, J.M. [Universidad Autónoma de Nuevo León, UANL, Facultad de Ciencias Químicas, Cd. Universitaria, San Nicolás de los Garza, Nuevo León, C.P. 66451 Nuevo León (Mexico); Group of Analytical Chemistry, Automation and Environment, University of Balearic Islands, Cra. Valldemossa km 7.5, 07122 Palma de Mallorca (Spain); Portugal, L.; Ferrer, L. [Group of Analytical Chemistry, Automation and Environment, University of Balearic Islands, Cra. Valldemossa km 7.5, 07122 Palma de Mallorca (Spain); Guzmán-Mar, J.L.; Hernández-Ramírez, A. [Universidad Autónoma de Nuevo León, UANL, Facultad de Ciencias Químicas, Cd. Universitaria, San Nicolás de los Garza, Nuevo León, C.P. 66451 Nuevo León (Mexico); Cerdà, V. [Group of Analytical Chemistry, Automation and Environment, University of Balearic Islands, Cra. Valldemossa km 7.5, 07122 Palma de Mallorca (Spain); Hinojosa-Reyes, L., E-mail: laura.hinojosary@uanl.edu.mx [Universidad Autónoma de Nuevo León, UANL, Facultad de Ciencias Químicas, Cd. Universitaria, San Nicolás de los Garza, Nuevo León, C.P. 66451 Nuevo León (Mexico)

    2015-05-18

    Highlights: • A fully automated flow-based modified-BCR extraction method was developed to evaluate the extractable As of soil. • The MSFIA–HG-AFS system included an UV photo-oxidation step for organic species degradation. • The accuracy and precision of the proposed method were found satisfactory. • The time analysis can be reduced up to eight times by using the proposed flow-based BCR method. • The labile As (F1 + F2) was <50% of total As in soil samples from As-contaminated-mining zones. - Abstract: A fully automated modified three-step BCR flow-through sequential extraction method was developed for the fractionation of the arsenic (As) content from agricultural soil based on a multi-syringe flow injection analysis (MSFIA) system coupled to hydride generation-atomic fluorescence spectrometry (HG-AFS). Critical parameters that affect the performance of the automated system were optimized by exploiting a multivariate approach using a Doehlert design. The validation of the flow-based modified-BCR method was carried out by comparison with the conventional BCR method. Thus, the total As content was determined in the following three fractions: fraction 1 (F1), the acid-soluble or interchangeable fraction; fraction 2 (F2), the reducible fraction; and fraction 3 (F3), the oxidizable fraction. The limits of detection (LOD) were 4.0, 3.4, and 23.6 μg L{sup −1} for F1, F2, and F3, respectively. A wide working concentration range was obtained for the analysis of each fraction, i.e., 0.013–0.800, 0.011–0.900 and 0.079–1.400 mg L{sup −1} for F1, F2, and F3, respectively. The precision of the automated MSFIA–HG-AFS system, expressed as the relative standard deviation (RSD), was evaluated for a 200 μg L{sup −1} As standard solution, and RSD values between 5 and 8% were achieved for the three BCR fractions. The new modified three-step BCR flow-based sequential extraction method was satisfactorily applied for arsenic fractionation in real agricultural

  19. Random Estimate the values of seed oil of Cucurbita maxima by refractive index method.

    Science.gov (United States)

    Saxena, R B

    2010-01-01

    The crude oil having lower iodine and free fatty acids values has Aamdosha properties. These properties are present due to toxic and anti-toxic compounds. These compounds can be harmful for the special diseases and may be unsaturated, saturated, open chain etc. The adulteration can take part as catalytic action for the toxic effect for the special diseases. Toxic properties of oils are removed by different ingrediants and methods. C. maxima seed tail (mst) is used with food and medicine. The present paper deals with the study of oil by refractive index and equations.

  20. On the anodic aluminium oxide refractive index of nanoporous templates

    International Nuclear Information System (INIS)

    Hierro-Rodriguez, A; Rocha-Rodrigues, P; Araujo, J P; Valdés-Bango, F; Alameda, J M; Teixeira, J M; Jorge, P A S; Santos, J L; Guerreiro, A

    2015-01-01

    In the present study, we have determined the intrinsic refractive index of anodic aluminium oxide, which is originated by the formation of nanoporous alumina templates. Different templates have been fabricated by the conventional two-step anodization procedure in oxalic acid. Their porosities were modified by chemical wet etching allowing the tuning of their effective refractive indexes (air-filled nanopores  +  anodic aluminium oxide). By standard spectroscopic light transmission measurements, the effective refractive index for each different template was extracted in the VIS–NIR region. The determination of the intrinsic anodic aluminium oxide refractive index was performed by using the Maxwell–Garnett homogenization theory. The results are coincident for all the fabricated samples. The obtained refractive index (∼1.55) is quite lower (∼22%) than the commonly used Al 2 O 3 handbook value (∼1.75), showing that the amorphous nature of the anodic oxide structure strongly conditions its optical properties. This difference is critical for the correct design and modeling of optical plasmonic metamaterials based on anodic aluminium oxide nanoporous templates. (paper)

  1. Short bowel mucosal morphology, proliferation and inflammation at first and repeat STEP procedures.

    Science.gov (United States)

    Mutanen, Annika; Barrett, Meredith; Feng, Yongjia; Lohi, Jouko; Rabah, Raja; Teitelbaum, Daniel H; Pakarinen, Mikko P

    2018-04-17

    Although serial transverse enteroplasty (STEP) improves function of dilated short bowel, a significant proportion of patients require repeat surgery. To address underlying reasons for unsuccessful STEP, we compared small intestinal mucosal characteristics between initial and repeat STEP procedures in children with short bowel syndrome (SBS). Fifteen SBS children, who underwent 13 first and 7 repeat STEP procedures with full thickness small bowel samples at median age 1.5 years (IQR 0.7-3.7) were included. The specimens were analyzed histologically for mucosal morphology, inflammation and muscular thickness. Mucosal proliferation and apoptosis was analyzed with MIB1 and Tunel immunohistochemistry. Median small bowel length increased 42% by initial STEP and 13% by repeat STEP (p=0.05), while enteral caloric intake increased from 6% to 36% (p=0.07) during 14 (12-42) months between the procedures. Abnormal mucosal inflammation was frequently observed both at initial (69%) and additional STEP (86%, p=0.52) surgery. Villus height, crypt depth, enterocyte proliferation and apoptosis as well as muscular thickness were comparable at first and repeat STEP (p>0.05 for all). Patients, who required repeat STEP tended to be younger (p=0.057) with less apoptotic crypt cells (p=0.031) at first STEP. Absence of ileocecal valve associated with increased intraepithelial leukocyte count and reduced crypt cell proliferation index (pSTEP. Persistent inflammation and lacking mucosal growth may contribute to continuing bowel dysfunction in SBS children, who require repeat STEP procedure, especially after removal of the ileocecal valve. Level IV, retrospective study. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. Simultaneous measurement of refractive index and temperature based on intensity demodulation using matching grating method.

    Science.gov (United States)

    Qi, Liang; Zhao, Chun-Liu; Kang, Juan; Jin, Yongxing; Wang, Jianfeng; Ye, Manping; Jin, Shangzhong

    2013-07-01

    A solution refractive index (SRI) and temperature simultaneous measurement sensor with intensity-demodulation system based on matching grating method were demonstrated. Long period grating written in a photonic crystal fiber (LPG-PCF), provides temperature stable and wavelength dependent optical intensity transmission. The reflective peaks of two fiber Bragg gratings (FBGs), one of which is etched then sensitive to both SRI and temperature, another (FBG2) is only sensitive to temperature, were located in the same linear range of the LPG-PCF's transmission spectrum. An identical FBG with FBG2 was chosen as a matching FBG. When environments (SRI and temperature) change, the wavelength shifts of the FBGs are translated effectively to the reflection intensity changes. By monitoring output lights of unmatching and matching paths, the SRI and temperature were deduced by a signal processing unit. Experimental results show that the simultaneous refractive index and temperature measurement system work well. The proposed sensor system is compact and suitable for in situ applications at lower cost.

  3. Assessing Gait Impairments Based on Auto-Encoded Patterns of Mahalanobis Distances from Consecutive Steps.

    Science.gov (United States)

    Muñoz-Organero, Mario; Davies, Richard; Mawson, Sue

    2017-01-01

    Insole pressure sensors capture the force distribution patterns during the stance phase while walking. By comparing patterns obtained from healthy individuals to patients suffering different medical conditions based on a given similarity measure, automatic impairment indexes can be computed in order to help in applications such as rehabilitation. This paper uses the data sensed from insole pressure sensors for a group of healthy controls to train an auto-encoder using patterns of stochastic distances in series of consecutive steps while walking at normal speeds. Two experiment groups are compared to the healthy control group: a group of patients suffering knee pain and a group of post-stroke survivors. The Mahalanobis distance is computed for every single step by each participant compared to the entire dataset sensed from healthy controls. The computed distances for consecutive steps are fed into the previously trained autoencoder and the average error is used to assess how close the walking segment is to the autogenerated model from healthy controls. The results show that automatic distortion indexes can be used to assess each participant as compared to normal patterns computed from healthy controls. The stochastic distances observed for the group of stroke survivors are bigger than those for the people with knee pain.

  4. Seismic data two-step recovery approach combining sparsity-promoting and hyperbolic Radon transform methods

    International Nuclear Information System (INIS)

    Wang, Hanchuang; Chen, Shengchang; Ren, Haoran; Liang, Donghui; Zhou, Huamin; She, Deping

    2015-01-01

    In current research of seismic data recovery problems, the sparsity-promoting method usually produces an insufficient recovery result at the locations of null traces. The HRT (hyperbolic Radon transform) method can be applied to problems of seismic data recovery with approximately hyperbolic events. Influenced by deviations of hyperbolic characteristics between real and ideal travel-time curves, some spurious events are usually introduced and the recovery effect of intermediate and far-offset traces is worse than that of near-offset traces. Sparsity-promoting recovery is primarily dependent on the sparsity of seismic data in the sparse transform domain (i.e. on the local waveform characteristics), whereas HRT recovery is severely affected by the global characteristics of the seismic events. Inspired by the above conclusion, a two-step recovery approach combining sparsity-promoting and time-invariant HRT methods is proposed, which is based on both local and global characteristics of the seismic data. Two implementation strategies are presented in detail, and the selection criteria of the relevant strategies is also discussed. Numerical examples of synthetic and real data verify that the new approach can achieve a better recovery effect by simultaneously overcoming the shortcomings of sparsity-promoting recovery and HRT recovery. (paper)

  5. Step-By-Step: Life Cycle Radioactive Waste Management

    International Nuclear Information System (INIS)

    2014-01-01

    Radioactive waste is an unavoidable by-product when nuclear technologies are used for electricity production and for beneficial practices in medicine, agriculture, research and industry. When the radioactivity of the waste is above a certain threshold, the waste requires special disposal methods. Through extensive research, standards and approaches have been developed for safely and securely preparing for and managing radioactive waste disposal. In the course of its journey from the point of generation to disposal, radioactive waste undergoes a number of predisposal management treatment steps to transform it into a safe, stable and manageable form suitable for transport, storage and disposal

  6. M-step preconditioned conjugate gradient methods

    Science.gov (United States)

    Adams, L.

    1983-01-01

    Preconditioned conjugate gradient methods for solving sparse symmetric and positive finite systems of linear equations are described. Necessary and sufficient conditions are given for when these preconditioners can be used and an analysis of their effectiveness is given. Efficient computer implementations of these methods are discussed and results on the CYBER 203 and the Finite Element Machine under construction at NASA Langley Research Center are included.

  7. Image Vector Quantization codec indexes filtering

    Directory of Open Access Journals (Sweden)

    Lakhdar Moulay Abdelmounaim

    2012-01-01

    Full Text Available Vector Quantisation (VQ is an efficient coding algorithm that has been widely used in the field of video and image coding, due to its fast decoding efficiency. However, the indexes of VQ are sometimes lost because of signal interference during the transmission. In this paper, we propose an efficient estimation method to conceal and recover the lost indexes on the decoder side, to avoid re-transmitting the whole image again. If the image or video has the limitation of a period of validity, re-transmitting the data wastes the resources of time and network bandwidth. Therefore, using the originally received correct data to estimate and recover the lost data is efficient in time-constrained situations, such as network conferencing or mobile transmissions. In nature images, the pixels are correlated with their neighbours and VQ partitions the image into sub-blocks and quantises them to the indexes that are transmitted; the correlation between adjacent indexes is very strong. There are two parts of the proposed method. The first is pre-processing and the second is an estimation process. In pre-processing, we modify the order of codevectors in the VQ codebook to increase the correlation among the neighbouring vectors. We then use a special filtering method in the estimation process. Using conventional VQ to compress the Lena image and transmit it without any loss of index can achieve a PSNR of 30.429 dB on the decoder. The simulation results demonstrate that our method can estimate the indexes to achieve PSNR values of 29.084 and 28.327 dB when the loss rate is 0.5% and 1%, respectively.

  8. Error analysis and system improvements in phase-stepping methods for photoelasticity

    International Nuclear Information System (INIS)

    Wenyan Ji

    1997-11-01

    In the past automated photoelasticity has been demonstrated to be one of the most efficient technique for determining the complete state of stress in a 3-D component. However, the measurement accuracy, which depends on many aspects of both the theoretical foundations and experimental procedures, has not been studied properly. The objective of this thesis is to reveal the intrinsic properties of the errors, provide methods for reducing them and finally improve the system accuracy. A general formulation for a polariscope with all the optical elements in an arbitrary orientation was deduced using the method of Mueller Matrices. The deduction of this formulation indicates an inherent connectivity among the optical elements and gives a knowledge of the errors. In addition, this formulation also shows a common foundation among the photoelastic techniques, consequently, these techniques share many common error sources. The phase-stepping system proposed by Patterson and Wang was used as an exemplar to analyse the errors and provide the proposed improvements. This system can be divided into four parts according to their function, namely the optical system, light source, image acquisition equipment and image analysis software. All the possible error sources were investigated separately and the methods for reducing the influence of the errors and improving the system accuracy are presented. To identify the contribution of each possible error to the final system output, a model was used to simulate the errors and analyse their consequences. Therefore the contribution to the results from different error sources can be estimated quantitatively and finally the accuracy of the systems can be improved. For a conventional polariscope, the system accuracy can be as high as 99.23% for the fringe order and the error less than 5 degrees for the isoclinic angle. The PSIOS system is limited to the low fringe orders. For a fringe order of less than 1.5, the accuracy is 94.60% for fringe

  9. A comparison of ground reaction force components according to the foothold heights in 16-t truck during downward step.

    Science.gov (United States)

    Hyun, Seung-Hyun; Ryew, Che-Cheong

    2017-12-01

    The aim of this study is to compare and analyze the components of ground reaction force (GRF) relative to the foothold heights during downward step of 16-t truck. Adult males (n= 10) jumped downward from each 1st, 2nd, 3rd foothold step and driver's seat orderly using hand rail. Sampling rate of force components of 3 axis (medial-lateral [ML] GRF, anterior-posterior [AP] GRF, peak vertical force [PVF]), variables (COPx, COPy, COP area) of center of pressure (COP), loading rate, and stability index (ML, AP, vertical, and dynamic postural stability index [DPSI]) processed from GRF system was cut off at 1,000 Hz. and variables was processed with repeated one-way analysis of variance. AP GRF, PVF and loading rate showed higher value in case of not used hand rail than that used hand rail in all 1st, 2nd, and 3rd of foothold step. DPSI showed more lowered stability in order of 2nd, 3rd step than 1st foothold step used with hand rail, of which showed lowest stability from driver's seat. COPx, COPy, and COP area showed higher value in case of 2nd and 3rd than that of 1st of foothold step, and showed lowest stability from driver's seat. It is more desirable for cargo truck driver to utilize an available hand rail in order of 3rd, 2nd, and 1st of foothold step than downward stepping directly, thus by which may results in decrease of falling injuries and minimization of impulsive force transferring to muscular-skeletal system.

  10. Step Sizes for Strong Stability Preservation with Downwind-Biased Operators

    KAUST Repository

    Ketcheson, David I.

    2011-08-04

    Strong stability preserving (SSP) integrators for initial value ODEs preserve temporal monotonicity solution properties in arbitrary norms. All existing SSP methods, including implicit methods, either require small step sizes or achieve only first order accuracy. It is possible to achieve more relaxed step size restrictions in the discretization of hyperbolic PDEs through the use of both upwind- and downwind-biased semidiscretizations. We investigate bounds on the maximum SSP step size for methods that include negative coefficients and downwind-biased semi-discretizations. We prove that the downwind SSP coefficient for linear multistep methods of order greater than one is at most equal to two, while the downwind SSP coefficient for explicit Runge–Kutta methods is at most equal to the number of stages of the method. In contrast, the maximal downwind SSP coefficient for second order Runge–Kutta methods is shown to be unbounded. We present a class of such methods with arbitrarily large SSP coefficient and demonstrate that they achieve second order accuracy for large CFL number.

  11. Two-step versus one-step FT4 assays in heparin treated patients and non-thyroidal illness

    International Nuclear Information System (INIS)

    Reiners, C.; Bieler, G.; Ertl, G.; Gloss, H.; Boerner, W.

    1985-01-01

    The primary intention of this study is to inform the clinician about the direction and the order of magnitude of possible disturbances of different FT 4 parameters under the condition mentioned last, which is not uncommon in daily routine. No single FT 4 -RIA proved be valid in severe NTI. There is the risk to misinterprete hyperthyroidism as euthyroidism with 1step assays and the possibility to classify euthyroid patients falsely as hyperthyroid with 2step assays. In relation to this problem, the sometimes lowered FT 4 values by 1step methods are clinically not so important. It has to be established, wether TSH assays of high sensitivity are able to overcome some of the difficulties with determinations of peripheral thyroid hormones in NTI. (orig./MG)

  12. Newmark local time stepping on high-performance computing architectures

    KAUST Repository

    Rietmann, Max

    2016-11-25

    In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100×). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

  13. Newmark local time stepping on high-performance computing architectures

    KAUST Repository

    Rietmann, Max; Grote, Marcus; Peter, Daniel; Schenk, Olaf

    2016-01-01

    In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100×). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

  14. Newmark local time stepping on high-performance computing architectures

    Energy Technology Data Exchange (ETDEWEB)

    Rietmann, Max, E-mail: max.rietmann@erdw.ethz.ch [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland); Institute of Geophysics, ETH Zurich (Switzerland); Grote, Marcus, E-mail: marcus.grote@unibas.ch [Department of Mathematics and Computer Science, University of Basel (Switzerland); Peter, Daniel, E-mail: daniel.peter@kaust.edu.sa [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland); Institute of Geophysics, ETH Zurich (Switzerland); Schenk, Olaf, E-mail: olaf.schenk@usi.ch [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland)

    2017-04-01

    In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100x). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

  15. Distribution of photon strength in nuclei by a method of two-step cascades

    International Nuclear Information System (INIS)

    Becvar, F.; Cejnar, P.; Kopecky, J.

    1990-01-01

    The applicability of sum-coincidence measurements of two-step cascade γ-ray spectra to the determination of photon strength functions at intermediate γ-ray energies (3 or 4 MeV) is discussed. An experiment based on thermal neutron capture in Nd was undertaken at the Brookhaven National Laboratory High Flux Beam Reactor to test this model. To understand the role of various uncertainties in similar experiments a series of model calculations was performed. We present an analysis of our experimental data which demonstrates the high sensitivity of the method to E1 and M1 photon strength functions. Our experimental data are in sharp contradiction to those expected from an E1 photon strength distributed according to the classical Lorentzian form with an energy invariant damping width. An alternative distribution of Kadmenskij et al., which violates Brink's Hypothesis, is strongly preferred. 13 refs., 5 figs

  16. Single-step digital backpropagation for nonlinearity mitigation

    DEFF Research Database (Denmark)

    Secondini, Marco; Rommel, Simon; Meloni, Gianluca

    2015-01-01

    Nonlinearity mitigation based on the enhanced split-step Fourier method (ESSFM) for the implementation of low-complexity digital backpropagation (DBP) is investigated and experimentally demonstrated. After reviewing the main computational aspects of DBP and of the conventional split-step Fourier...... in the computational complexity, power consumption, and latency with respect to a simple feed-forward equalizer for bulk dispersion compensation....

  17. Step dynamics and terrace-width distribution on flame-annealed gold films: The effect of step-step interaction

    International Nuclear Information System (INIS)

    Shimoni, Nira; Ayal, Shai; Millo, Oded

    2000-01-01

    Dynamics of atomic steps and the terrace-width distribution within step bunches on flame-annealed gold films are studied using scanning tunneling microscopy. The distribution is narrower than commonly observed for vicinal planes and has a Gaussian shape, indicating a short-range repulsive interaction between the steps, with an apparently large interaction constant. The dynamics of the atomic steps, on the other hand, appear to be influenced, in addition to these short-range interactions, also by a longer-range attraction of steps towards step bunches. Both types of interactions promote self-ordering of terrace structures on the surface. When current is driven through the films a step-fingering instability sets in, reminiscent of the Bales-Zangwill instability

  18. Qualitative and quantitative assessment of step size adaptation rules

    DEFF Research Database (Denmark)

    Krause, Oswin; Glasmachers, Tobias; Igel, Christian

    2017-01-01

    We present a comparison of step size adaptation methods for evolution strategies, covering recent developments in the field. Following recent work by Hansen et al. we formulate a concise list of performance criteria: a) fast convergence of the mean, b) near-optimal fixed point of the normalized s...... that cumulative step size adaptation (CSA) and twopoint adaptation (TPA) provide reliable estimates of the optimal step size. We further find that removing the evolution path of CSA still leads to a reliable algorithm without the computational requirements of CSA.......We present a comparison of step size adaptation methods for evolution strategies, covering recent developments in the field. Following recent work by Hansen et al. we formulate a concise list of performance criteria: a) fast convergence of the mean, b) near-optimal fixed point of the normalized...

  19. Methods for slow axis beam quality improvement of high power broad area diode lasers

    Science.gov (United States)

    An, Haiyan; Xiong, Yihan; Jiang, Ching-Long J.; Schmidt, Berthold; Treusch, Georg

    2014-03-01

    For high brightness direct diode laser systems, it is of fundamental importance to improve the slow axis beam quality of the incorporated laser diodes regardless what beam combining technology is applied. To further advance our products in terms of increased brightness at a high power level, we must optimize the slow axis beam quality despite the far field blooming at high current levels. The later is caused predominantly by the built-in index step in combination with the thermal lens effect. Most of the methods for beam quality improvements reported in publications sacrifice the device efficiency and reliable output power. In order to improve the beam quality as well as maintain the efficiency and reliable output power, we investigated methods of influencing local heat generation to reduce the thermal gradient across the slow axis direction, optimizing the built-in index step and discriminating high order modes. Based on our findings, we have combined different methods in our new device design. Subsequently, the beam parameter product (BPP) of a 10% fill factor bar has improved by approximately 30% at 7 W/emitter without efficiency penalty. This technology has enabled fiber coupled high brightness multi-kilowatt direct diode laser systems. In this paper, we will elaborate on the methods used as well as the results achieved.

  20. Effectiveness of author-assigned keywords to INIS indexing

    International Nuclear Information System (INIS)

    Yokoo, Hiroshi; Takahashi, Satoko; Habara, Tadashi

    1977-01-01

    A test was carried out on the quality of indexing data which is based only upon author-assigned keywords in order to appreciate effectiveness of the keywords. As measures of the quality, the retrievability and the consistency of the indexing data were evaluated by comparison with the case of the conventional indexing method under the circumstances of the INIS descriptor assignment to the journal articles of the Atomic Energy Society of Japan. The indexing consistency obtained was approximately 0.61 on an average (or 0.66 when the narrower-broader hierarchical relations were regarded as consistent ones). Of the hit, noise, or total documents retrieved with the conventional indexing data, 0.86, 0.27, or 0.71, respectively, were retrievable with the keywords-based indexing data. From the results the recall ratio for the keywords-based indexing is estimated to be no less than 0.86 of that for the conventional indexing method, and the consistency of the hit documents are to be 0.75 at least. Consequently, the author-assigned keywords proved to be very effective to the document indexing. (auth.)