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Sample records for metamizol mas d-propoxifeno

  1. Metamizol bij postoperatieve pijnbestrijding

    NARCIS (Netherlands)

    Koster, Harriëtte T.; Avis, Hans J.; Stevens, Markus F.; Hollmann, Markus W.

    2012-01-01

    Postoperative pain management is an essential part of surgical management. In the Netherlands paracetamol, NSAIDs and, if necessary, opioids are the most commonly used drugs for perioperative analgesia. Metamizole is a non-opioid analgesic that is rarely used in the Netherlands, although it is one

  2. Agranulocytosis after Metamizole Sodium Use

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    Eren Cagan

    2015-09-01

    Full Text Available Metamizole sodium (Novalgine is commonly used as an antipyretic, analgesic, and spasmolytic agent in some parts of the world and our country; however, it is banned in developed countries because of severe side effects. Here we present a case of a three-years- four- months-old girl who developed life-threatening agranulocytosis in his bone marrow after metamizole sodium use for fever, which resolved with granulocyte colony-stimulating factor therapy. [Cukurova Med J 2015; 40(3.000: 580-583

  3. Cellulitis Developing After Intramuscular Metamizole Injection

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    Onur Ozturk

    2016-12-01

    Full Text Available If the suitable technique is not used in intramuscular injection applications and the injection area is not detected correctly, complications may be observed. Our patient was given intramuscular Metamizole in his house and then he had cellulitis with necrosis area. Following an antibiotic treatment, tissue defect was primarily covered with gluteal muscle skin flap. Cellulitis development after metamizole injection is not common still potential side effects should be considered before prescription.

  4. Chronic use of metamizole: not so safe after all?

    NARCIS (Netherlands)

    Vuik, F.E.; Koehestanie, P.; Herbers, A.H.; Terhaar sive Droste, J.S.

    2017-01-01

    Metamizole can be used in both short- and long-term pain relief therapies and has a relatively favourable safety profile compared with classic NSAIDs. Metamizole is also infamous because of its potential fatal adverse drug reaction, agranulocytosis. Although this risk varies, it is estimated to

  5. Diclofenac and metamizol in postoperative analgesia in plastic surgery.

    Science.gov (United States)

    Saray, A; Büyükkocak, U; Cinel, I; Tellioglu, A T; Oral, U

    2001-01-01

    Postoperative pain relief after major surgery cannot be achieved with opioids alone in all patients without respiratory depression or other significant drawbacks. Modern medical practice, therefore, dictates the use of alternative analgesic agents as an adjunct or substitute to minimize the deleterious effects and to facilitate an earlier return to work and daily activities. Diclofenac and metamizol inhibit prostaglandin synthesis, thus attenuate the peripheral nociceptive sensitization caused by the surgical trauma. This investigation was conducted to determine the potency of diclofenac compared with metamizol in the control of postoperative pain after various plastic surgical operations under general anesthesia. A multiple-dose, randomized, double-blind clinical trial composed of one hundred and sixty-six patients was conducted. Group M patients received 1 g intramuscular metamizol (every 8 hours) and Group D patients received 75 mg intramuscular diclofenac (every 12 hours). Additional analgesia requirements were recorded and meperidine was used as the complementary analgesic when needed. Pain was assessed by visual analogue scores. Platelet count and bleeding time analyses were performed preoperatively and on the first postoperative day. Metamizol decreased the additional analgesia requirement during the 18 hours following surgery. This was also associated with significantly lower pain scores. There was no significant difference between the patients receiving either metamizol or diclofenac in terms of pain scores, additional request for analgesia and frequency of side effects from the 18th until the 48th hour postoperatively. However, the use of diclofenac was associated with reduced side effects, though a reduction in platelet number and prolongation of bleeding time was noted in the majority of the patients receiving diclofenac. Metamizol is significantly superior to diclofenac for the reduction of postoperative pain after plastic surgery in the first 18 hours

  6. Pain medication in German nursing homes: a whole lot of metamizole.

    Science.gov (United States)

    Hoffmann, Falk; Schmiemann, Guido

    2016-06-01

    Prescribing of metamizole (dipyrone), an analgesic that has been withdrawn from the market or never approved in many countries owing to safety concerns, is high in elder persons in Germany. This study assessed the use of pain medications in German nursing homes with a special focus on prescribing patterns of metamizole. Using data of the 'Inappropriate Medication in Patients with Renal Insufficiency in Nursing Homes' (IMREN) study conducted between October 2014 and April 2015 in nursing homes in Bremen and Lower Saxony, we studied prescribing of analgesics including both scheduled and as-needed medications. For residents with scheduled medication, dosage and duration of use were analysed. A total of 852 residents from 21 nursing homes were included. They were on average 83.5 years old, and 76.5% were women; 73.8% received at least one analgesic with 70.3% obtaining World Health Organization step I drugs. The most frequently prescribed substances were metamizole (for 40.6%) and paracetamol (acetaminophen; 35.6%), with paracetamol given mostly as-needed. The proportion of residents receiving metamizole increased with age (up to 47.4% in persons aged 90 years and over). Of 143 residents with scheduled metamizole (16.8%), the mean daily dosage was 1843 mg (interquartile range [IQR]: 1500-2250); 66.9% received metamizole for at least 90 days and 23.2% for at least 365 days (mean duration 276 days; IQR: 59-314). There is a discrepancy between prescribing of metamizole for older persons, on the one hand, and evidence on comparative effectiveness and safety as well as approval and recommendations, on the other hand. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  7. Effect of piroxicam, metamizol, and S-adenosylmethionine in a murine model of experimental trichomoniasis

    Directory of Open Access Journals (Sweden)

    Nogal-Ruiz J.J.

    2005-03-01

    Full Text Available Biological effects of piroxicam, metamizol, and S-adenosylmethionine (S-AMET have been tested in NMRI mice infected intraperitoneally with Trichomonas vaginalis. An intraperitoneal treatment during ten preinfection days with piroxicam (10 mg/Kg/day, or metamizol (275 mg/Kg/day, but not with S-AMET (17 mg/Kg/day induced a significant decrease of abdominal lesions and mortality, assessed by means of a pathogenicity index. The trichomonicidal activity of piroxicam, metamizol, and S-AMET was tested in vitro at the concentration of 300 μM, but found ineffective. These assays have shown the usefulness of the experimental trichomoniasis model for the study of the immunomodulating activity of synthetic drugs.

  8. Prevention of dipyrone (metamizole) induced inhibition of aspirin antiplatelet effects.

    Science.gov (United States)

    Polzin, Amin; Richter, Stefan; Schrör, Karsten; Rassaf, Tienush; Merx, Marc W; Kelm, Malte; Hohlfeld, Thomas; Zeus, Tobias

    2015-07-01

    We have recently shown that dipyrone (metamizole), a non-opioid analgesic, can nullify aspirin (acetylsalicylic acid; ASA) antiplatelet effects in patients with coronary artery disease (CAD). In this study, we analysed the aspirin and dipyrone drug-drug interaction in order to identify strategies to prevent the dipyrone induced inhibition of asprin antiplatelet effects. Platelet function was measured by arachidonic acid-induced light-transmission aggregometry, thromboxane (TX) B2- formation by immunoassay. Dipyrone metabolite plasma levels were determined by high-performance-liquid-chromatography (HPLC). In seven healthy individuals, in vitro ASA (30 µM/ 100 µM/ 300 µM/ 1,000 µM) and dipyrone (10 µM) coincubation revealed, that the aspirin and dipyrone interaction can be overcome by increasing doses of aspirin. In 36 aspirin and dipyrone comedicated CAD patients, addition of ASA (30 µM/ 100 µM) in vitro inhibited, but did not completely overcome the dipyrone induced reduction of aspirin antiplatelet effects. Notably, the inhibition of thromboxane formation in aspirin and dipyrone comedicated CAD patients coincided with dipyrone plasma levels. In a cross-over designed study in four healthy individuals, we were able to prove that inhibition of aspirin (100 mg/ day) effects by dipyrone (750 mg/ day) was reversible. Furthermore, aspirin (100 mg/ day) medication prior to dipyrone (750 mg/ day) intake prevented the inhibition of antiplatelet effects by dipyrone in 12 healthy individuals. In conclusion, aspirin medication prior to dipyrone intake preserves antiplatelet effects, circumventing the pharmacodynamic drug-drug interaction at the level of cyclooxygenase-1.

  9. KETOROLACO VERSUS METAMIZOL EN EL TRATAMIENTO DEL DOLOR POSOPERATORIO EN NIÑOS

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    Gloria Pamella Palo Núñez

    2015-12-01

    Full Text Available Objective: Evaluate the effectiveness of Ketorolac and Metamizol in the treatment of acute postoperative pain of adenotonsillectomy in children three to six years old receiving medical care in the Department of Anesthesiology at the Hospital Alberto Sabogal Sologuren during the period 2012-2013. Material and Methods: Observational, descriptive, retrospective and cross-sectional study. The study involved 115 children who underwent elective adenotonsillectomy whose ages were between three to six years old. They are according to two groups that received analgesic therapy in the operating room, 58 children received Metamizol and 57 children received Ketorolac. Results: In the group receiving Ketorolac, 56.1% had no pain in the postanesthesic recovery unit according to the scale of Oucher and 43.9% had mild to moderate pain (1-6. The group that received Metamizol, 19% of children reported pain and 74.1% rated their pain from mild to moderate. The degree of pain relief measured Oucher scale was higher in patients receiving Ketorolac (p <0.05. Conclusions: Reducing postoperative pain in adenotonsillectomy in children with Ketorolaco is higher than Metamizol.

  10. Influence of different excipients on the properties of hard gelatin capsules with metamizole sodium

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    Rogowska Magdalena

    2016-09-01

    Full Text Available Metamizole is an effective non-opioid analgesic drug used in the treatment of acute and chronic pain. Due to induced potentially life-threatening blood disorders, metamizole was withdrawn from market in many parts of the world, however, it is one of the most popular analgesics in Poland that is available as an over the counter drug. Patients tend to prefer capsules over tablets, as they are easier to swallow and taste better. The powder-filled capsules also have greater bioavailability and require less excipients, as compared to tablets. Polymic excipients are mainly used in capsule filling, and have influence upon the physico-chemical properties of the hard gelatin capsules and the powder formulation. The aim of the study was to determine whether various combinations of polymers impact the disintegration time and pharmaceutical availability of hard gelatin capsules with metamizole sodium. The results of our work demonstrated that the 80% of all active substance was released in all tested formulations within 15 minutes. Herein, the capsule containing lactose monohydrate had the longest release (4% after 2 min., while capsules containing mannitol had the fastest release (81.2% after 2 min.. Moreover, the addition of HPMC to capsules with lactose brought about a slight increase in the metamizole release rate, while the addition of PVP 30 to capsules with microcrystalline cellulose slightly accelerated release. This data suggests that the use of different polymers in capsules formulation brings about changes in the physical properties of powders and modifies the release profile of metamizole. In our study, the most preferred formulation was one containing microcrystalline cellulose (good powder properties and fairly fast release.

  11. Adsorption Of Metamizole Sodium By Activated Carbon In Simulated Gastric And Intestinal Fluids

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    Elif Çalışkan Salihi

    2017-12-01

    Full Text Available In vitro adsorption of metamizole sodium by activated carbon was studied at pH 1.2 and 7.5 in order to simulate gastric and intestinal fluids. In the first 5 minutes, more than eighty percent of the total adsorption occurred but the adsorption process achieved to the equilibrium in 1 hour. Time to reach equilibrium was not changed with the changing pH, the concentration of the adsorbate or the adsorbent amount. The equilibrium data followed the Langmuir model and therefore fitted to L-type in accordance with the Giles classification for adsorption isotherms. The maximum removal capacities of the activated carbon for metamizole sodium were calculated using Langmuir equation and found as 185.19 mg/g and 161.29 mg/g at pH 1.2 and 7.5, respectively.

  12. [Hemodynamic and antipyretic effects of paracetamol, metamizol and dexketoprofen in critical patients].

    Science.gov (United States)

    Vera, P; Zapata, L; Gich, I; Mancebo, J; Betbesé, A J

    2012-12-01

    The objective was to study the antipyretic and hemodynamic effects of three different drugs used to treat fever in critically ill patients. Prospective, observational study in a 16-bed, general ICU of a university hospital. We studied 150 patients who had a febrile episode (temperature>38°C): 50 received paracetamol, 50 metamizol and 50 dexketoprofen. None. Body temperature, systolic, diastolic and mean arterial pressure, heart rate, central venous pressure and oxygen saturation were determined at baseline and at 30, 60 and 120minutes after infusion of the drug. Additionally, we recorded temperature 180minutes after starting drug infusion. Diuresis and the need for or change of dose of vasodilator or vasoconstrictor drugs were also recorded. Patient characteristics, baseline temperature and hemodynamics were similar in all groups. We observed a significant decrease of at least 1°C in temperature after 180minutes in 38 patients treated with dexketoprofen (76%), in 36 with metamizol (72%), and in 20 with paracetamol (40%) (pdexketoprofen (p=0.005). Dexketoprofen was the most effective antipyretic agent at the doses tested. Although all three drugs reduced mean arterial pressure, the reduction with paracetamol was less pronounced. Copyright © 2011 Elsevier España, S.L. and SEMICYUC. All rights reserved.

  13. Lysine clonixinate versus dipyrone (metamizole for the acute treatment of severe migraine attacks: a single-blind, randomized study Clonixinato de lisina versus dipirona (metamizol para o tratamento agudo de uma crise intensa de enxaqueca: estudo monocego e randomizado

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    Abouch Valenty Krymchantowski

    2008-06-01

    Full Text Available BACKGROUND AND OBJECTIVE: Nonsteroidal anti-inflammatory drugs (NSAID are effective to treat migraine attacks. Lysine clonixinate (LC and dipyrone (metamizol have been proven effective to treat acute migraine. The aim of this study was to evaluate the efficacy and tolerability of the intravenous formulations of LC and dipyrone in the treatment of severe migraine attacks. METHOD: Thirty patients (28 women, 2 men, aged 18 to 48 years with migraine according the International Headache Society (IHS (2004 were studied. The patients were randomized into 2 groups when presenting to an emergency department with a severe migraine attack. The study was single-blind. Headache intensity, nausea, photophobia and side effects were evaluated at 0, 30, 60 and 90 minutes after the drug administration. Rectal indomethacin as rescue medication (RM was available after 2 hours and its use compared between groups. RESULTS: All patients completed the study. At 30 minutes, 0% of the dipyrone group 13% of the LC group were pain free (p=0.46. At 60 and 90 minutes, 2 (13% and 5 (33% patients from the dipyrone group and 11 (73% and 13 (86.7% patients from the LC group were pain free (pCONTEXTO E OBJETIVO: Antiinflamatórios não esteroidais (AINE são eficazes no tratamento de crises de enxaqueca. O objetivo deste estudo foi comparar a eficácia e a tolerabilidade das apresentações injetáveis do clonixinato de lisina (CL e da dipirona no tratamento de crises intensas de enxaqueca. MÉTODO: Trinta pacientes (28 mulheres, 2 homens, com idades entre 18 e 48 anos e enxaqueca de acordo com a Classificação Internacional de Cefaléias (2004 foram estudados. Os pacientes foram randomizados em 2 grupos ao se apresentarem em uma unidade de emergência, com uma crise intensa de enxaqueca. O desenho do estudo foi monocego. A intensidade da cefaléia, a presença de náusea e fotofobia e os efeitos colaterais foram avaliados e comparados na administração das drogas e após 30

  14. Effects on growth of human osteoblast-like cells of three nonsteroidal anti-inflammatory drugs: metamizole, dexketoprofen, and ketorolac.

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    De Luna-Bertos, Elvira; Ramos-Torrecillas, Javier; Manzano-Moreno, Francisco Javier; García-Martínez, Olga; Ruiz, Concepción

    2015-01-01

    Some nonsteroidal anti-inflammatory drugs (NSAIDs) have adverse effects on bone tissue. The objective of this study was to determine the effect of different doses of dexketoprofen, ketorolac, and metamizole on growth of the osteoblast MG63 cell line. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide spectrophotometry results showed that MG63 cell growth was significantly inhibited after 24 hr of culture with doses of 10, 20, 100, or 1,000 µM of each NSAID and with doses of 0.1, 1, or 5 µM of dexketoprofen and ketorolac but not metamizole. Cell-cycle studies revealed that dexketoprofen and ketorolac treatments significantly arrested the cell cycle in phase G0/G1, increasing the percentage of cells in this phase. Apoptosis/necrosis studies showed significant changes versus control cells, with an increased percentage of cells in apoptosis after treatment with 10, 100, or 1,000 µM of metamizole and after treatment with 1, 10, 100, or 1,000 µM of dexketoprofen or ketorolac. In conclusion, treatment of osteoblast-like cells with high doses of the NSAIDs tested increased not only the percentage of cells in apoptosis but also the percentage of necrotic cells. © The Author(s) 2014.

  15. Selective venous vasodilator properties of the analgesic metamizole (dipyrone) in a human ex vivo model-implications for postoperative pain management.

    Science.gov (United States)

    Hoenicka, Markus; Gorki, Hagen; Traeger, Karl; Liebold, Andreas

    2017-05-01

    Metamizole (dipyrone) is a first-line, non-opioid analgesic used for postoperative pain management. Clinical data and animal experiments indicate a possible vasodilator action of this drug. We investigated the effects of metamizole on human artery and vein tone in an ex vivo model to assess potential contributions to venous pooling. Excess segments of bypass grafts were harvested during coronary artery bypass grafting procedures. Tensions were measured in an organ bath for 120 min after adding metamizole to the preconstricted vessels. Contribution of endothelium was assessed in endothelium-denuded vessels, and indometacin was used to identify cyclooxygenase-mediated effects. Internal mammary arteries (n = 6) constricted after addition of 1, 3, and 10 μM metamizole and remained constricted at the lower doses. Transient constrictions also occurred in saphenous veins (n = 20), but veins relaxed below solvent controls after 20 min at all concentrations. Endothelium removal (n = 12) and cyclooxygenase inhibition (n = 12) suppressed the vasoconstrictor effect but not the vasodilator effect. Metamizole and its metabolites display counteracting effects on blood vessel tone ex vivo. The vasoconstrictor effect is mediated by cyclooxygenase-derived products. The net effect is site-specific, resulting in a selective venous vasodilator action. This may exacerbate unwanted venous pooling during postoperative pain therapy.

  16. E/Z MAS demonstration

    International Nuclear Information System (INIS)

    Boor, M.G.; Hurford, J.M.; Landry, R.P.; Martinez, B.J.; Solem, A.M.; Whiteson, R.; Zardecki, A.

    1998-01-01

    Los Alamos National Laboratory has developed E/Z MAS, a new generation nuclear material accountability application based on the latest technology and designed for facilities required to track nuclear materials with a simple-to-use interface. E/Z MAS is based on years of experience spent developing nuclear material accounting systems. E/Z MAS uses a modern relational database with a web server and enables users on a classified local area network to interact with the database with web browsers. The E/Z MAS Demonstration poster session demonstrates the E/Z MAS functions required by an operational nuclear facility to track material as it enters and leaves a facility and to account for the material as it moves through a process. The generation of internal facility reports and external reports for the Russian Federal system will be demonstrated. Bar-code readers will be used to demonstrate the ability of EZ MAS to automate certain functions, such as physical inventories at facilities

  17. In vitro interference by acetaminophen, aspirin, and metamizole in serum measurements of glucose, urea, and creatinine.

    Science.gov (United States)

    Luna-Záizar, Hilda; Virgen-Montelongo, María; Cortez-Álvarez, Cesar R; Ruiz-Quezada, Sandra L; Escutia-Gutiérrez, Raymundo; García-Lemus, Cuauhtémoc R; Mendizabal-Ruiz, Adriana P

    2015-05-01

    Here we aimed to investigate the in vitro effects of three analgesic-antipyretic drugs frequently used in clinical practice in Mexico - acetaminophen (AAP), aspirin (ASA) and metamizole (MMZ) - on serum measurements of glucose, urea, and creatinine. Each analyte was measured in a base-serum pool spiked with the drugs at subtherapeutic, therapeutic, and toxic doses. Serum glucose and urea were measured using the hexokinase/G-6PDH and urease/GLDH kinetic assays, respectively. Serum creatinine (SCr) was measured with a Jaffe procedure based on the alkaline-picrate reaction and with an enzymatic dry-chemistry system. Measurements were carried out in IL-Monarch and Vitros DT60-II analyzers, respectively. Data were analyzed by the difference-paired interference test and by ANOVA. By the kinetic Jaffe/Monarch procedure, we found positive interference by the drugs on the SCr measurements and by only ASA for urea measurement. For creatinine measurements, the total errors (TEs) were 22-51%, 18-105%, and 15-26% for AAP, ASA, and MMZ respectively, while for urea measurement the TE was 16-21% for ASA. A negative interference by MMZ on SCr (TE=-47%), but no-interference for AAP or ASA, were found via the enzymatic/DT60-II system. In vitro positive interference induced by AAP, ASA, and MMZ (via the alkaline-picrate reaction), or negative interference by MMZ (via a dry-chemistry system), on the SCr measurements highlights the importance of investigating all possible sources of variation that may alter the accuracy of the laboratory tests, in order to provide useful results for making medical decisions for optimal patient care. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  18. High Tech M&As

    DEFF Research Database (Denmark)

    Toppenberg, Gustav

    2013-01-01

    of findings are not applicable to the high-tech industry; in fact this industry has many additional challenges. In this study, we aim to explore the process of M&A in the high-tech industry by drawing on extant literature and empirical field work. The paper outlines a research project in progress which...... intends to provide theoretical, empirical and practical contributions in answering the research question: what role does Operations and IT play in creating value in high-tech M&As? The research adds a needed perspective on M&A literature by unveiling unique challenges and opportunities faced by the M......&A teams in this sector. The phenomenon is studied from multiple perspectives: integration team, acquiring group and the company being acquired....

  19. Influences of hot climate and metamizol treatment on physiological responses, blood constituents and productivity of baladi goats

    International Nuclear Information System (INIS)

    Aboulnaga, A.I.; Kamal, T.H.; Abusinna, G.; Amer, M.M.

    1992-01-01

    Nine lactating baladi goats (2.5 years old and 17 Kg b. wt.) were maintained in the climatic chamber for 3 successive experimental periods of 7 days each. The first was mild climate exposure (15 - 20 degree C and 50 - 25% R.H.) . The second was heat exposure of 35 degree C and 25% R.H. from 7 a.m. to 15 p.m. and about 20 degree C and 28% R.H. during the remaining 16 hours. The third was the same previous hot climate exposure but the goats were injected daily with 30 mg/Kg B.wt./day with metamizol ( novalgin ) . Under heat stress conditions, goats injected with novalgin tended to restore the heat-induced changes in most biological parameters studied to their initial levels. There were significant increases in RBC; plasma T 4 , Na, Ca, P, Mg, and cholesterol; body weight ( B.wt. ), milk yield ( M.Y.) and significant decreases in rectal temperature (RT), respiration rate (RR) and pulse rate (PR), as compared with the corresponding parameters of the same heat-stressed goats prior to novalgin administration.1 tab

  20. MAS NMR of HIV-1 protein assemblies

    Science.gov (United States)

    Suiter, Christopher L.; Quinn, Caitlin M.; Lu, Manman; Hou, Guangjin; Zhang, Huilan; Polenova, Tatyana

    2015-04-01

    The negative global impact of the AIDS pandemic is well known. In this perspective article, the utility of magic angle spinning (MAS) NMR spectroscopy to answer pressing questions related to the structure and dynamics of HIV-1 protein assemblies is examined. In recent years, MAS NMR has undergone major technological developments enabling studies of large viral assemblies. We discuss some of these evolving methods and technologies and provide a perspective on the current state of MAS NMR as applied to the investigations into structure and dynamics of HIV-1 assemblies of CA capsid protein and of Gag maturation intermediates.

  1. Transfer of pharmacopoeial liquid chromatography reversedphase methods for determination of related compounds in diclofenac sodium and metamizole sodium from conventional to core-shell column

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    Katerina Brezovska

    2015-04-01

    Full Text Available Core-shell silica particles were developed as a new material for chromatographic stationary phases in order to provide fast and high efficiency separations of small and large molecules and complex samples, at pressures compatible with conventional HPLC equipment. The aim of our work was to show the applicability of the HPLC columns based on a core-shell technology for determination of related substances in diclofenac sodium and in metamizole sodium using the methods described in the corresponding monographs of the European pharmacopoeia. The obtained results have shown that the proposed methods can be successfully transferred on core shell column, with suitable adjustment of injection volume and flow rate. The advantage of using core-shell column is fast and highly efficient separation on conventional HPLC equipment with increased sensitivity of the method and high throughput of the analysis, providing enhanced lab productivity and reduced costs.

  2. TCSP ER-2 MODIS AIRBORNE SIMULATOR (MAS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The TCSP ER-2 MODIS Airborne Simulator (MAS) dataset was collected by a MODIS Airborne Simulator (MAS), which is a multi-spectral line-scanner system that acquires...

  3. Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle.

    Science.gov (United States)

    Valenzuela, Fermín; García-Saisó, Sebastián; Lemini, Cristina; Ramírez-Solares, Rafael; Vidrio, Horacio; Mendoza-Fernández, Víctor

    2005-08-01

    Clinically metamizol (MZ) has been related to alteration on haemodynamic parameters and modifications on blood pressure in humans when administered intravenously. These effects have been observed at MZ therapeutic doses. Experimentally, MZ is able to induce relaxation on several types of vascular smooth muscles and modulates the contraction induced by phenylephrine. However, the mechanism underlying the MZ effects on vascular reactivity is not clear. Potassium channels (K) present on vascular smooth muscle cells closely regulate the vascular reactivity and membrane potential. There are four described types of K in vascular tissue: K voltage sensitive (K(V)), K calcium sensitive (K(Ca)2+), K ATP sensitive (K(ATP) and K inward rectification (K(IR), voltage sensitive). The aim of this work was to investigate MZ effects on angiotensin II (AT II) and noradrenaline (NA) induced contraction and to evaluate the K participation on MZ modulating effect on vascular smooth muscle contraction, using isometric and patch clamp techniques. MZ induces relaxation in a concentration dependent manner. Furthermore, MZ strongly inhibits in a concentration dependent fashion the contraction induced by AT II. However, MZ inhibition on NA induced contraction was moderated compared with that observed on AT II. MZ effects on AT II induced contraction was blocked by glybenclamide (a specific K(ATP) blocker, 3 microM, *p < 0.01). In patch clamp experiments, MZ (3 mM) induces an increase on potassium current (K+) mediated by K(ATP) in similar way as diazoxide (a specific K(ATP) opener, 3 microM). Our results suggest that MZ induces relaxation and inhibits contraction induced by AT II acting as a K(ATP) opener.

  4. SAFARI 2000 MODIS Airborne Simulator (MAS) Browse Images

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS Airborne Simulator (MAS) collected imagery for the SAFARI 2000 field campaign. Currently available data consist of browse imagery and flight track...

  5. CAMEX-4 ER-2 MODIS AIRBORNE SIMULATOR (MAS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS Airborne Simulator (MAS) is an airborne scanning spectrometer that acquires high spatial resolution imagery of cloud and surface features from its vantage...

  6. TCSP ER-2 MODIS AIRBORNE SIMULATOR (MAS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS Airborne Simulator (MAS) is a multi-spectral line-scanner system that acquires image data in 50 spectral bands over wavelengths ranging from 0.46 to 14.3...

  7. Increased vascular sympathetic modulation in mice with Mas receptor deficiency

    Science.gov (United States)

    Rabello Casali, Karina; Ravizzoni Dartora, Daniela; Moura, Marina; Bertagnolli, Mariane; Bader, Michael; Haibara, Andrea; Alenina, Natalia; Irigoyen, Maria Claudia; Santos, Robson A

    2016-01-01

    Introduction: The angiotensin-converting enzyme 2 (ACE2)/angiotensin (Ang)-(1–7)/Mas axis could modulate the heart rate (HR) and blood pressure variabilities (BPV) which are important predictors of cardiovascular risk and provide information about the autonomic modulation of the cardiovascular system. Therefore we investigated the effect of Mas deficiency on autonomic modulation in wild type and Mas-knockout (KO) mice. Methods: Blood pressure was recorded at high sample rate (4000 Hz). Stationary sequences of 200–250 beats were randomly chosen. Frequency domain analysis of HR and BPV was performed with an autoregressive algorithm on the pulse interval sequences and on respective systolic sequences. Results: The KO group presented an increase of systolic arterial pressure (SAP; 127.26±11.20 vs 135.07±6.98 mmHg), BPV (3.54±1.54 vs 5.87±2.12 mmHg2), and low-frequency component of systolic BPV (0.12±0.11 vs 0.47±0.34 mmHg2). Conclusions: The deletion of Mas receptor is associated with an increase of SAP and with an increased BPV, indicating alterations in autonomic control. Increase of sympathetic vascular modulation in absence of Mas evidences the important role of Ang-(1–7)/Mas on cardiovascular regulation. Moreover, the absence of significant changes in HR and HRV can indicate an adaptation of autonomic cardiac balance. Our results suggest that the Ang-(1–7)/Mas axis seems more important in autonomic modulation of arterial pressure than HR. PMID:27080540

  8. Pollen morphology of Cornus mas L. and Cornus sanguinea L.

    OpenAIRE

    Karlıoğlu Kılıç, Nurgül; Tuttu, Gamze

    2017-01-01

    Pollen morphology of Cornus mas L. and Cornus sanguinea L.Abstract: The pollen morphology of 2 species of the genus Cornus L. distributed in Turkey was studied with light and scanning electron microscope. The pollen of genus Cornus is 3-colporate. Pollen of the Cornus mas is spheroidal and Cornus sanguinea is subprolate. Size varies of Cornus mas pollen with the polar axis ranging from 21.54 to 27.36 μm and equatorial axis from 21.31 to 26.72 μm. Size varies of Cornus sanguinea pollen with po...

  9. MAS2-8 radar and digital control unit

    Science.gov (United States)

    Oberg, J. M.; Ulaby, F. T.

    1974-01-01

    The design of the MAS 2-8 (2 to 8 GHz microwave-active spectrometer), a ground-based sensor system, is presented. A major modification in 1974 to the MAS 2-8, that of a control subsystem to automate the data-taking operation, is the prime focus. The digital control unit automatically changes all system parameters except FM rate and records the return signal on paper tape. The overall system operation and a detailed discussion of the design and operation of the digital control unit are presented.

  10. KINERJA USAHA TANAMAN HIAS POTONG PT PESONA DAUN MAS ASRI

    Directory of Open Access Journals (Sweden)

    Muhamad Arief Bangun Sanjaya

    2017-01-01

    Full Text Available Pesona Daun Mas Asri is a company in cut flowers  and leaves cultivation. The  achievement is shown by the performance of the company. The overall company’s performance contributes in developing the company’s vision. Balanced score card is a management tool used to observe and maintain the stability between financial indicators (financial perspective and non financial indicators (customer, business internal process, growth and learning.  The objective of the journal is to plan the performance of the company using balanced scorecard approach, analyze and calculate the vision, mission and strategy implemented by Pesona Daun Mas in it business activity..  The result for every strategic target shows that the performance of Pesona Daun Mas is excellent with the achieved score of 78,04%.  However the target for the selling growth level and marketing activities are classified as average which means that it still needs to be developed.   Keywords:  balanced scorecard, performance evaluation, KPI performance index, ornamental plants cutAbstrakPesona Daun Mas Asri merupakan perusahaan yang bergerak dalam bidang budi daya bunga potong dan daun potong. Pencapaian dalam menjalankan sebuah perusahaan dapat dilihat dari kinerja perusahaan tersebut.Kinerja perusahaan Pesona Daun Mas Asri secara keseluruhan dapat berkontribusi untuk mengembangkan perusahaan dalam mencapai visi. Balanced scorecard adalah salah satu alat manajemen yang dapat melihat dan menjaga keseimbangan antara indikator keuangan (perspektif keuangan dan indikator non-keuangan (pelanggan, proses bisnisinternal, pertumbuhan dan pembelajaran. Tujuan dari jurnal ini adalah untuk merancang pengukuran kinerja perusahaan dengan pendekatan Balanced scorecard. Penelitian ini juga bertujuan menganalisis dan mengukur pelaksanaan visi, misi dan strategi yang dijalankan oleh Pesona Daun Mas Asri dalam kegiatan bisnisnya. Selain itu, memberikan saran dan rekomendasi, serta merumuskan implikasi

  11. The evolution of the MasAgro hubs

    NARCIS (Netherlands)

    Camacho-Villa, Tania Carolina; Almekinders, Conny; Hellin, Jon; Martinez-Cruz, Tania Eulalia; Rendon-Medel, Roberto; Guevara-Hernández, Francisco; Beuchelt, Tina D.; Govaerts, Bram

    2016-01-01

    Purpose: Little is known about effective ways to operationalize agricultural innovation processes. We use the MasAgro program in Mexico (which aims to increase maize and wheat productivity, profitability and sustainability), and the experiences of middle level ‘hub managers’, to understand how

  12. 48 CFR 538.271 - MAS contract awards.

    Science.gov (United States)

    2010-10-01

    ... price/discount relationship between the Government and the identified commercial customer (or category... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false MAS contract awards. 538... CATEGORIES OF CONTRACTING FEDERAL SUPPLY SCHEDULE CONTRACTING Establishing and Administering Federal Supply...

  13. Meconium aspiration syndrome (MAS) - Where do we go? Research perspectives.

    Science.gov (United States)

    Kääpä, Pekka O

    2009-10-01

    The pathogenetic cascade of meconium aspiration syndrome (MAS) in newborn infants is complex and still incompletely studied. The variable clinical presentation of MAS is basically connected with variation of the amount and consistency of aspirated meconium and also its distribution within the affected lungs. The contributing role of other factors, like intrauterine fetal compromises, lung maturity at the time of insult as well as direct and indirect effects of meconium and its components on the lung alveolar and vascular integrity and development, remains to be studied in further detail. Better understanding of the lung injury processes in MAS, specifically inflammatory injury and non-inflammatory apoptosis and their interplay, may offer new possibilities to treat the severely affected infants, and needs therefore to be explored. Systemic dispersion of intrapulmonary meconium and its components may further induce inflammatory circulatory changes and injurious effects in distant organs, but the mechanisms and clinical significance of these systemic complications are still poorly known. It is thus evident that lung injury processes and potent long-term consequences in various extrapulmonary organs, specifically the brain, as well as development of new approaches to their treatment and prevention form great challenges for future research of MAS.

  14. ERP sistēmas ieviešana

    OpenAIRE

    Proskurins, Aleksandrs

    2008-01-01

    Šajā darbā tika apskatīta informācijas sistēmu klasifikācija, uzņēmuma resursu plānošanas sistēmas (ERP) definīcija un tās vieta IS klasifikācijā. Tika apskatīti ERP sistēmu ieviešanas teorētiskie aspekti, izstrādes un pielāgošanas specifika, kā arī tika izanalizēti vairāki ERP sistēmas ieviešanas projekti Latvijas uzņēmumos.

  15. The MicroMAS CubeSat Mission

    Science.gov (United States)

    Cahoy, K.; Blackwell, W. J.; Allen, G.; Bury, M.; Efromson, R.; Galbraith, C.; Hancock, T.; Leslie, V.; Osaretin, I.; Retherford, L.; Scarito, M.; Shields, M.; Toher, D.; Wight, K.; Miller, D.; Marinan, A.; Paek, S.; Peters, E.; Schmidt, F. H.; Alvisio, B.; Wise, E.; Masterson, R.; Franzim Miranda, D.; Crail, C.; Kingsbury, R.; Souffrant, A.; Orrego, L.; Eslinger, G.; Nicholas, A.; Pong, C.

    2012-12-01

    The recently published Midterm Assessment of NASA's Implementation of the Decadal Survey finds that, "The nation's Earth observing system is beginning a rapid decline in capability as long-running missions end and key new missions are delayed, lost, or canceled. The projected loss of observing capability could have significant adverse consequences for science and society." In this presentation, we explore low-cost, mission-flexible, and rapidly deployable spaceborne sensors that can meet stringent performance requirements pervading the NASA Earth Science measurement programs, including especially the recommended NRC Decadal Survey missions. New technologies have enabled a novel approach toward this science observational goal, and in this paper we describe recent technology develop efforts to address the challenges above through the use of CubeSat radiometers. The Micro-sized Microwave Atmospheric Satellite (MicroMAS) is a 3U cubesat (30x10x10 cm, ~4kg) hosting a passive microwave spectrometer operating near the 118.75-GHz oxygen absorption line. The focus of the first MicroMAS mission (hereafter, MicroMAS-1) is to observe convective thunderstorms, tropical cyclones, and hurricanes from a near-equatorial orbit at approximately 500-km altitude. A MicroMAS flight unit is currently being developed in anticipation of a 2014 launch to be provided by NASA. A parabolic reflector is mechanically rotated as the spacecraft orbits the earth, thus directing a cross-track scanned beam with FWHM beamwidth of 2.4-degrees, yielding an approximately 25-km diameter footprint from a nominal altitude of 500 km. Radiometric calibration is carried out using observations of cold space, the earth's limb, and an internal noise diode that is weakly coupled through the RF front-end electronics. A key technology feature is the development of an ultra-compact intermediate frequency processor module for channelization, detection, and A-to-D conversion. The antenna system and RF front

  16. PROPAGANDA POLITIK PARTAI GERINDRA DALAM GAME MAS GARUDA PADA PEMILU 2014 (Analisis Deskriptif Game Online Mas Garuda

    Directory of Open Access Journals (Sweden)

    Angga Satrya Putra

    2016-03-01

    Full Text Available The purpose of this study was to determine how the meaning of the look and content of the online game “Garuda Mas”. This game contains aspects of politically charged designations so that it can become a propaganda technique. The subject of this study is the game “Garuda Mas” which has been input on social media Facebook.Methods of data collection using documentary and literature. Data analysis using descriptive techniques. Data validity checking techniques using triangulation source.The results showed that the game “MAS GARUDA” can form the perspective of the players against Mas Garuda as a superhero figure hopes the Indonesian people who are able to overcome all the problems that exist in Indonesia. This game is a form of creative campaigns using propaganda techniques inserted in the game that has the power to change the mindset of every player. Change of mindset occurs because the player did not have an opportunity to think critically on aspects marking contained in the game. By indirectly the players will feel the emotional of this game and assume characterizations “Garuda Mas” in this game is a truth that can be believed.Keywords: Descriptive, Online Games, Mas Garuda, Partai Gerindra

  17. Perancangan Dan Pembuatan Sistem Informasi Administrasi Pada Toko Jamur Mas

    OpenAIRE

    -, Yosep; Setiawan, Alexander; Rostianingsih, Silvia

    2013-01-01

    Jamur Mas is a store which sell and buy goods of daily needs. This store has some problems, which are counting of profit and loss, inventory and account receivable and account payable list. Problems that occur are in the recording, where all the recording is still done manually, this recording has a big risk.To answer these problems, then made an application, this application is developed and made with Microsoft Visual Studio 2005.Net and Microsoft SQL Server 2005 as a data storage. This appl...

  18. Angiotensin type 2 receptor (AT2R) and receptor Mas

    DEFF Research Database (Denmark)

    Villela, Daniel; Leonhardt, Julia; Patel, Neal

    2015-01-01

    The angiotensin type 2 receptor (AT2R) and the receptor Mas are components of the protective arms of the renin-angiotensin system (RAS), i.e. they both mediate tissue protective and regenerative actions. The spectrum of actions of these two receptors and their signalling mechanisms display striking...... the phenomenon of blockade of angiotensin-(1-7) [Ang-(1-7)] actions by AT2R antagonists and vice versa. Such mechanisms may comprise dimerization of the receptors or dimerization-independent mechanisms such as lack of specificity of the receptor ligands used in the experiments or involvement of the Ang-(1...

  19. Measuring proton shift tensors with ultrafast MAS NMR.

    Science.gov (United States)

    Miah, Habeeba K; Bennett, David A; Iuga, Dinu; Titman, Jeremy J

    2013-10-01

    A new proton anisotropic-isotropic shift correlation experiment is described which operates with ultrafast MAS, resulting in good resolution of isotropic proton shifts in the detection dimension. The new experiment makes use of a recoupling sequence designed using symmetry principles which reintroduces the proton chemical shift anisotropy in the indirect dimension. The experiment has been used to measure the proton shift tensor parameters for the OH hydrogen-bonded protons in tyrosine·HCl and citric acid at Larmor frequencies of up to 850 MHz. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. A General Protocol for Temperature Calibration of MAS NMR Probes at Arbitrary Spinning Speeds

    Science.gov (United States)

    Guan, Xudong; Stark, Ruth E.

    2010-01-01

    A protocol using 207Pb NMR of solid lead nitrate was developed to determine the temperature of magic-angle spinning (MAS) NMR probes over a range of nominal set temperatures and spinning speeds. Using BioMAS and fastMAS probes with typical sample spinning rates of 8 and 35 kHz, respectively, empirical equations were devised to predict the respective sample temperatures. These procedures provide a straightforward recipe for temperature calibration of any MAS probe. PMID:21036557

  1. Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.

    Science.gov (United States)

    Burghi, Valeria; Fernández, Natalia Cristina; Gándola, Yamila Belén; Piazza, Verónica Gabriela; Quiroga, Diego Tomás; Guilhen Mario, Érica; Felix Braga, Janaína; Bader, Michael; Santos, Robson Augusto Souza; Dominici, Fernando Pablo; Muñoz, Marina Cecilia

    2017-01-01

    Mas receptor (MasR) is a G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang (1-7) protective axis of renin-angiotensin system. Because the role of this receptor is not definitively clarified, determination of MasR tissue distribution and expression levels constitutes a critical knowledge to fully understanding its function. Commercially available antibodies have been widely employed for MasR protein localization and quantification, but they have not been adequately validated. In this study, we carried on an exhaustive evaluation of four commercial MasR antibodies, following previously established criteria. Western Blotting (WB) and immunohistochemistry studies starting from hearts and kidneys from wild type (WT) mice revealed that antibodies raised against different MasR domains yielded different patterns of reactivity. Furthermore, staining patterns appeared identical in samples from MasR knockout (MasR-KO) mice. We verified by polymerase chain reaction analysis that the MasR-KO mice used were truly deficient in this receptor as MAS transcripts were undetectable in either heart or kidney from this animal model. In addition, we evaluated the ability of the antibodies to detect the human c-myc-tagged MasR overexpressed in human embryonic kidney cells. Three antibodies were capable of detecting the MasR either by WB or by immunofluorescence, reproducing the patterns obtained with an anti c-myc antibody. In conclusion, although three of the selected antibodies were able to detect MasR protein at high expression levels observed in a transfected cell line, they failed to detect this receptor in mice tissues at physiological expression levels. As a consequence, validated antibodies that can recognize and detect the MasR at physiological levels are still lacking.

  2. TOKSISITAS LETAL MOLUSKISIDA NIKLOSAMIDA PADA BENIH IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Yosmaniar Yosmaniar

    2009-04-01

    Full Text Available Penggunaan moluskisida untuk menanggulangi hama dalam budidaya tanaman padi yang semakin meningkat berpotensi mencemari lingkungan perairan, karena mengandung residu dari bahan aktifnya. Moluskisida niklosamida (C13H8Cl2N2O4 merupakan bahan aktif pestisida yang digunakan untuk memberantas hama keong mas atau siput murbei (Pomacea sp. di sawah. Dengan demikian, bahan tersebut memiliki potensi untuk mencemari lahan tempat usaha budidaya ikan. Penelitian ini bertujuan untuk mengetahui potensi toksisitas akut niklosamida terhadap benih ikan mas (Cyprinus carpio yang ditunjukkan oleh nilai Median Lethal Concentration (LC50 24, 48, dan 96 jam. Penelitian dilakukan di Instalasi Riset Lingkungan Perikanan Budidaya dan Toksikologi, Cibalagung-Bogor. Menggunakan ikan mas dengan bobot individu 2,47 ± 0,13 g. Moluskisida yang digunakan mengandung bahan aktif niklosamida 250g/L. Wadah pengujian berupa 21 unit akuarium kaca berukuran 40 cm x 20 cm x 20 cm yang dilengkapi aerasi serta saluran pemasukan dan pengeluaran. Jumlah ikan uji setiap wadah 10 ekor dengan peubah yang diukur adalah mortalitas ikan. Selama penelitian ikan tidak diberi makan. Tahapan penelitian terdiri atas penentuan nilai ambang atas-bawah, nilai lethal time dan LC50 -24, 48, 72, dan 96 jam. Data diolah dengan analisis probit program LC50. Hasil penelitian menunjukkan bahwa nilai LC50-24, 48, 72, dan 96 jam terhadap benih ikan mas adalah 0,8012 (0,7140—0,8990; 0,5999 (0,5356—0,6719; 0,4511 (0,4067—0,5004; dan 0,3849 mg/L (0,3684—0,4061. Hal ini menunjukkan niklosamida termasuk pestisida yang memiliki toksisitas sangat tinggi (golongan A. The use of molluscicide in aquatic as well as in terresterial agro ecosystem without properly controlled may produce detrimental effects on freshwater fisheries. Molluscicide utilization for golden apple snail (Pomacea sp. control in rice field has increased. The ingredient potencially has a possibility to pollute aquaculture water. The

  3. Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.

    Science.gov (United States)

    Lazaroni, Thiago L N; Raslan, Ana Cláudia S; Fontes, Walkiria R P; de Oliveira, Marilene L; Bader, Michael; Alenina, Natalia; Moraes, Márcio F D; Dos Santos, Robson A; Pereira, Grace S

    2012-01-01

    It has been shown that the brain has its own intrinsic renin-angiotensin system (RAS) and angiotensin-(1-7) (Ang-(1-7)) is particularly interesting, because it appears to counterbalance most of the Ang II effects. Ang-(1-7) exerts its biological function through activation of the G-protein-coupled receptor Mas. Interestingly, hippocampus is one of the regions with higher expression of Mas. However, the role of Ang-(1-7)/Mas axis in hippocampus-dependent memories is still poorly understood. Here we demonstrated that Mas ablation, as well as the blockade of Mas in the CA1-hippocampus, impaired object recognition memory (ORM). We also demonstrated that the blockade of Ang II receptors AT1, but not AT2, recovers ORM impairment of Mas-deficient mice. Considering that high concentrations of Ang-(1-7) may activate AT1 receptors, nonspecifically, we evaluate the levels of Ang-(1-7) and its main precursors Ang I and Ang II in the hippocampus of Mas-deficient mice. The Ang I and Ang II levels are unaltered in the whole hipocampus of MasKo. However, Ang-(1-7) concentration is increased in the whole hippocampus of MasKo mice, as well as in the CA1 area. Taken together, our findings suggest that the functionality of the Ang-(1-7)/Mas axis is essential for normal ORM processing. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Why does meconium cause meconium aspiration syndrome? Current concepts of MAS pathophysiology.

    Science.gov (United States)

    van Ierland, Y; de Beaufort, A J

    2009-10-01

    One in every 7 pregnancies ends with meconium-stained amniotic fluid and approximately 5% of these infants develop the meconium aspiration syndrome (MAS). MAS is a severe disease of the (mainly) term neonate, characterized by respiratory distress, pulmonary inflammation, persistent pulmonary hypertension and chronic hypoxia. The pathophysiology of MAS is multifactorial and complex. In this article, we discuss the mechanical and chemical effects of meconium on a newborn's airway, meconium-induced inflammation, mediated by proinflammatory cytokines and chemokines, the complement system and the proinflammatory enzyme phospholipase A2. Furthermore, we focus on MAS-related apoptotic cell death, causing severe acute lung injury due to damage and detachment of lung airway and alveolar cells. Finally, risk factors for MAS development to identify those newborns that develop MAS and those who do not are discussed.

  5. Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS.

    Science.gov (United States)

    Leonhardt, Julia; Villela, Daniel C; Teichmann, Anke; Münter, Lisa-Marie; Mayer, Magnus C; Mardahl, Maibritt; Kirsch, Sebastian; Namsolleck, Pawel; Lucht, Kristin; Benz, Verena; Alenina, Natalia; Daniell, Nicholas; Horiuchi, Masatsugu; Iwai, Masaru; Multhaup, Gerhard; Schülein, Ralf; Bader, Michael; Santos, Robson A; Unger, Thomas; Steckelings, Ulrike Muscha

    2017-06-01

    The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors of the protective arm of the renin-angiotensin system. They mediate strikingly similar actions. Moreover, in various studies, AT2R antagonists blocked the effects of MAS agonists and vice versa. Such cross-inhibition may indicate heterodimerization of these receptors. Therefore, this study investigated the molecular and functional interplay between MAS and the AT2R. Molecular interactions were assessed by fluorescence resonance energy transfer and by cross correlation spectroscopy in human embryonic kidney-293 cells transfected with vectors encoding fluorophore-tagged MAS or AT2R. Functional interaction of AT2R and MAS was studied in astrocytes with CX3C chemokine receptor-1 messenger RNA expression as readout. Coexpression of fluorophore-tagged AT2R and MAS resulted in a fluorescence resonance energy transfer efficiency of 10.8 ± 0.8%, indicating that AT2R and MAS are capable to form heterodimers. Heterodimerization was verified by competition experiments using untagged AT2R and MAS. Specificity of dimerization of AT2R and MAS was supported by lack of dimerization with the transient receptor potential cation channel, subfamily C-member 6. Dimerization of the AT2R was abolished when it was mutated at cysteine residue 35. AT2R and MAS stimulation with the respective agonists, Compound 21 or angiotensin-(1-7), significantly induced CX3C chemokine receptor-1 messenger RNA expression. Effects of each agonist were blocked by an AT2R antagonist (PD123319) and also by a MAS antagonist (A-779). Knockout of a single of these receptors made astrocytes unresponsive for both agonists. Our results suggest that MAS and the AT2R form heterodimers and that-at least in astrocytes-both receptors functionally depend on each other. © 2017 American Heart Association, Inc.

  6. Optimized Distribution of Beijing Population Based on CA-MAS

    Directory of Open Access Journals (Sweden)

    Haoguang Liang

    2017-01-01

    Full Text Available In recent years rapid expansion of populations, disruption of ecological environments, and power shortages to areas of high population density in undeveloped areas have appeared in major cities in China. Well-planned population distribution in a city has become one of the key development strategies of urbanization in the country. Taking Beijing as a case-study and using 2010 as the base period, this study simulates city population size and distribution during 2011–2030 using the CA-MAS model. The results showed that (1 the unplanned layout of Beijing’s population is inefficient and will result in the slow agglomeration of populations into surrounding small towns, (2 the suburbanization of the population (while employment opportunities remain centralized increases the stress of the city commuters, (3 the current policy guiding the distribution of residential and commercial areas is effective, accelerating the formation of small town clusters, which play a role in the city’s radiation and diffusion, contributing to reducing urban commuter stress, and (4 promoting the homogenization of public resources, planning the development of a multicenter urban area, and promoting mixed use (commercial and residential zoning are the main measures recommended to strengthen the sustainability of Beijing’s urban development and to optimize spatial layout.

  7. Characterization of coke by MAS 13C-NMR

    International Nuclear Information System (INIS)

    Nagy, J.B.; Tuel, A.; Munck, M.; Derouane, E.G.

    1991-01-01

    The molecular architecture of coke is difficult to determine. Nuclear magnetic resonance spectroscopy allows one to understand the chemical environment or types of hydrogen and carbon in the sample. It is also possible to estimate the proportion of atoms in the various environments. Here, liquid-state and solid-state NMR have been used to characterize different series of feedstocks and coke samples. Liquid phase 13 C NMR was used to analyse feeds and products separated by HPLC (PEW) in fractions called aliphatics, mono-, di-, tri-, and polyaromatics. An internal lock with deuterated chloroform was used due to the small amount of material present in each fraction. The NMR analysis gives the aromaticity and gives a nice correlation with the results obtained by GC/MS (average no of C-atoms in each fraction, chainlength, no. of substituents etc.). Structural features were gained by comparison of different fractions, while differences were seen, when feed and product were compared. For liquid samples, a model has been proposed in which the feed is supposed to be described as a mixture of six model compounds. Results concerning three series of feedstocks and the structural paramaters deduced from 13 C and 1 H NMR spectra are discussed and compared with the experimental data obtained from elemental analysis. In the solid state, by using Cross Polarization (CP) and Magic Angle Spinning (MAS), it is possible to obtain information on different carbon structural types. Structural parameters, such as the aromaticity f a or the H/C ratio can be evaluated with a good reliability. (AB) (23 refs.)

  8. E/Z MAS: An easy-to-use computerized materials control and accountability system

    International Nuclear Information System (INIS)

    Anderson, L.K.; Boor, M.G.; Hurford, J.M.; Landry, R.P.; Martinez, B.J.; Solem, A.M.; Whiteson, R.; Zardecki, A.

    1998-01-01

    Nuclear facilities that handle and process nuclear materials are required to track their nuclear holdings and to keep adequate records that manage and control the inventory of those holdings. The complexity of a system that does this job is directly proportional to the complexity of the facility's operations. This paper describes an approach to computerized materials protection, control, and accountability (MPC and A) that was introduced by Los Alamos National Laboratory (LANL) in the fall of 1997. This new system, E/Z MAS, is the latest addition to the LANL suite of computerized MPC and A tools, which also includes the CoreMAS system. E/Z MAS was initially designed to address the needs of those facilities that have small to modest MPC and A needs but has been expanded to provide full functionality for any facility. The system name, E/Z MAS, reflects the system's easy-to-use characteristics, which include ease of installation and ease of software maintenance. Both CoreMAS and E/Z MAS have been provided to facilities in the Former Soviet Union to assist them in implementing a computerized MPC and A system that meets their needs. In this paper the authors will address the functionality of CoreMAS and E/Z MAS, and an argument in favor of intranet-based material control and accountability will be advanced

  9. Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS

    DEFF Research Database (Denmark)

    Leonhardt, Julia; Villela, Daniel C.; Teichmann, Anke

    2017-01-01

    The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors of the protective arm of the renin-angiotensin system. They mediate strikingly similar actions. Moreover, in various studies, AT2R antagonists blocked the effects of MAS agonists and vice versa. Such cross-inhibition may......, subfamily C-member 6. Dimerization of the AT2R was abolished when it was mutated at cysteine residue 35. AT2R and MAS stimulation with the respective agonists, Compound 21 or angiotensin-(1-7), significantly induced CX3C chemokine receptor-1 messenger RNA expression. Effects of each agonist were blocked...

  10. Smoke, Clouds and Radiation Brazil NASA ER-2 Moderate Resolution Imaging Spectrometer (MODIS) Airborne Simulator (MAS) Data

    Data.gov (United States)

    National Aeronautics and Space Administration — SCARB_ER2_MAS data are Smoke, Clouds and Radiation Brazil (SCARB) NASA ER2 Moderate Resolution Imaging Spectrometer (MODIS) Airborne Simulator (MAS)...

  11. Multinuclear MAS NMR studies on coked zeolites H-ZSM-5

    International Nuclear Information System (INIS)

    Ernst, H.; Freude, D.; Hunger, M.; Pfeifer, H.

    1991-01-01

    During the cracking process carbonaceous materials are deposited on the outer or inner surface of the catalyst. These deposits are in many cases the main cause of catalyst deactivation. Magic angle spinning (MAS) NMR investigations and catalytic n-hexane cracking were carried out on H-ZSM-5 zeolites after a mild hydrothermal de-alumination. By 13 C CP MAS NMR it could be shown that the enhanced catalytic activity does not enhance the coke formation and that the chemical nature of these deposits is essentially aromatic. From 1 H MAS NMR studies performed on shallow-bed activated sealed samples and 27 Al and 29 Si MAS NMR on rehydrated samples it follows that for high coke concentrations the catalyst deactivation is caused mainly by blocking of Broensted acid sites. (author). 27 refs.; 3 figs.; 2 tabs

  12. Inactivation Of ACC Oxidase Acco During Modified Atmosphere Storage MAS Of Mango

    Directory of Open Access Journals (Sweden)

    E. Basuki

    2017-02-01

    Full Text Available Inactivation ACC Oxidase ACCO during Modified Atmosphere Storage MAS of Mango were carried out at Food Technology Laboratory University of Mataram from by using Completely Randomized Design and continued with Least Significant Different at five percent significance level. Mangoes were stored at Polyethylene PE bags PE KMnO4 Polypropylene bags PP PP KMnO4 and unpacked Control for three weeks. The physical properties of fruit such as weight loss and decay percentage were determined while physiological properties such as the rate of respiration ethylene production including ACCO activity. Inactivation of ACCO occurred to almost half-time of its activity in mango stored at MAS as compared to unpacked mango. Therefore paralleled the rate of respiration and production of ethylene at MAS leads to extend the storage life of mangoes. Weight loss and decay percentage of mango kept in MAS for 3 weeks were lower than unpacked.

  13. Hardware modification of a 7 mm MAS NMR probe to a single-crystal goniometer.

    Science.gov (United States)

    Kovács, Gábor; Rohonczy, János

    2006-07-01

    Tensorial terms of the Hamiltonian can be measured by solid-state single-crystal nuclear magnetic resonance (NMR) spectroscopy which requires a goniometer NMR probehead. Goniometer probes; however, are not standard parts of solid NMR spectrometers and are available only at a much higher price than magic-angle spinning (MAS) probeheads widely used in research. Due to requirements of MAS experiments, modern probeheads are designed for small ceramic rotors, which are 1-4 mm in diameter, to reach very high angular frequencies, so there are several older 7 mm MAS probeheads used rarely todays in NMR laboratories. In this paper, a simple method is presented how to rebuild step-by-step a 7 mm Bruker MAS probehead to be suitable for single-crystal spectroscopy. In the second part (31)P chemical shift tensors of Na(4)P(2)O(7) x 10H(2)O are determined to demonstrate the functionality of the rebuilt probehead.

  14. Preliminary studies concerning chromosome constitution of some Cornus mas L. genotypes (Bacau district)

    OpenAIRE

    Elena Truta; Gabriela Capraru; Craita-Maria Rosu; Stefania Surdu; Gogu Giorghita; Viorel Ionel Rati

    2009-01-01

    : The cytogenetic characterization is necessary to decipher the controversies on biogeography, taxonomy and evolution of the genus, evolution of chromosome number. Some of Cornus species have the following diploid chromosome numbers: Cornus suecica L. 2n=22, Cornus mas L. 2n=18, 54, Cornus sanguinea L. 2n=22, Cornus sericea L. 2n=22, Cornus alba 2n=22. Our preliminary observations performed on Cornus mas genotypes (Bacau district) confirmed the existence of 2n=18 chromosomes. Kary...

  15. A novel α/β-hydrolase gene IbMas enhances salt tolerance in transgenic sweetpotato.

    Directory of Open Access Journals (Sweden)

    Degao Liu

    Full Text Available Salt stress is one of the major environmental stresses in agriculture worldwide and affects crop productivity and quality. The development of crops with elevated levels of salt tolerance is therefore highly desirable. In the present study, a novel maspardin gene, named IbMas, was isolated from salt-tolerant sweetpotato (Ipomoea batatas (L. Lam. line ND98. IbMas contains maspardin domain and belongs to α/β-hydrolase superfamily. Expression of IbMas was up-regulated in sweetpotato under salt stress and ABA treatment. The IbMas-overexpressing sweetpotato (cv. Shangshu 19 plants exhibited significantly higher salt tolerance compared with the wild-type. Proline content was significantly increased, whereas malonaldehyde content was significantly decreased in the transgenic plants. The activities of superoxide dismutase (SOD and photosynthesis were significantly enhanced in the transgenic plants. H2O2 was also found to be significantly less accumulated in the transgenic plants than in the wild-type. Overexpression of IbMas up-regulated the salt stress responsive genes, including pyrroline-5-carboxylate synthase, pyrroline-5-carboxylate reductase, SOD, psbA and phosphoribulokinase genes, under salt stress. These findings suggest that overexpression of IbMas enhances salt tolerance of the transgenic sweetpotato plants by regulating osmotic balance, protecting membrane integrity and photosynthesis and increasing reactive oxygen species scavenging capacity.

  16. AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection.

    Science.gov (United States)

    da Costa Gonçalves, Andrey C; Fraga-Silva, Rodrigo A; Leite, Romulo; Santos, Robson A S

    2013-03-01

    The renin-angiotensin system plays a crucial role in erectile function. It has been shown that elevated levels of angiotensin II contribute to the development of erectile dysfunction both in humans and in aminals. On the contrary, the heptapeptide angiotensin-(1-7) appears to mediate penile erection by activation of the Mas receptor. Recently, we have shown that the erectile function of Mas gene-deleted mice was substantially reduced, which was associated with a marked increase in fibrous tissue in the corpus cavernosum. We have hypothesized that the synthetic non-peptide Mas agonist, AVE 0991, would potentiate penile erectile function. We showed that intracavernosal injection of AVE 0991 potentiated the erectile response of anaesthetized Wistar rats, measured as the ratio between corpus cavernosum pressure and mean arterial pressure, upon electrical stimulation of the major pelvic ganglion. The facilitatory effect of AVE 0991 on erectile function was dose dependent and completely blunted by the nitric oxide synthesis inhibitor, l-NAME. Importantly, concomitant intracavernosal infusion of the specific Mas receptor blocker, A-779, abolished the effect of AVE 0991. We demonstrated that AVE 0991 potentiates the penile erectile response through Mas in an NO-dependent manner. Importantly, these results suggest that Mas agonists, such as AVE 0991, might have significant therapeutic benefits for the treatment of erectile dysfunction.

  17. Neuroprotective Mechanisms of the ACE2-Angiotensin-(1-7)-Mas Axis in Stroke

    DEFF Research Database (Denmark)

    Bennion, Douglas M; Haltigan, Emily; Regenhardt, Robert W

    2015-01-01

    The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2-angiotensin-(1-7)-Mas axis [ACE2-Ang-(1-7)-Mas] in ischemic and hemorrhagic stroke has spurred interest in a more complete characterization of its mechanisms of action. Here, we summarize findings that desc......The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2-angiotensin-(1-7)-Mas axis [ACE2-Ang-(1-7)-Mas] in ischemic and hemorrhagic stroke has spurred interest in a more complete characterization of its mechanisms of action. Here, we summarize findings...... that describe the protective role of the ACE2-Ang-(1-7)-Mas axis in stroke, along with a focused discussion on the potential mechanisms of neuroprotective effects of Ang-(1-7) in stroke. The latter incorporates evidence describing the actions of Ang-(1-7) to counter the deleterious effects of angiotensin II...... complete understanding of the mechanisms of action of Ang-(1-7) to elicit neuroprotection will serve as an essential step toward research into potential targeted therapeutics in the clinical setting....

  18. Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene

    Directory of Open Access Journals (Sweden)

    T. Walther

    2000-01-01

    Full Text Available Heart rate variability is a relevant predictor of cardiovascular risk in humans. A significant genetic influence on heart rate variability is suggested, although the genes involved are ill-defined. The Mas-protooncogene encodes a G-protein-coupled receptor with seven transmembrane domains highly expressed in testis and brain. Since this receptor is supposed to interact with the signaling of angiotensin II, which is an important regulator of cardiovascular homeostasis, heart rate and blood pressure were analyzed in Mas-deficient mice. Using a femoral catheter the blood pressure of mice was measured for a period of 30 min and 250 data values per second were recorded. The mean values and range of heart rate and blood pressure were then calculated. Neither heart rate nor blood pressure were significantly different between knockout mice and controls. However, high resolution recording of these parameters and analysis of the data by non-linear dynamics revealed significant alterations in cardiovascular variability in Mas-deficient animals. In particular, females showed a strong reduction of heart rate variability. Furthermore, the data showed an increased sympathetic tone in knockout animals of both genders. The marked alterations detected in Mas-deficient mice of both genders suggest that the Mas-protooncogene is an important determinant of heart rate and blood pressure variability.

  19. Technology Enhanced Learning for People with Intellectual Disabilities and Cerebral Paralysis: The MAS Platform

    Science.gov (United States)

    Colomo-Palacios, Ricardo; Paniagua-Martín, Fernando; García-Crespo, Ángel; Ruiz-Mezcua, Belén

    Education for students with disabilities now takes place in a wide range of settings, thus, including a wider range of assistive tools. As a result of this, one of the most interesting application domains of technology enhanced learning is related to the adoption of learning technologies and designs for people with disabilities. Following this unstoppable trend, this paper presents MAS, a software platform aimed to help people with severe intellectual disabilities and cerebral paralysis in their learning processes. MAS, as a technology enhanced learning platform, provides several tools that supports learning and monitoring for people with special needs, including adaptative games, data processing and monitoring tools. Installed in a special needs education institution in Madrid, Spain, MAS provides special educators with a tool that improved students education processes.

  20. Muscle attachment site (MAS) patterns for species determination in European species of Lucilia (Diptera: Calliphoridae).

    Science.gov (United States)

    Niederegger, Senta; Szpila, Krzysztof; Mall, Gita

    2015-03-01

    Species identification is generally assessed to be more difficult in larval stages than in adult forms. Especially closely related species such as Lucilia caesar and Lucilia illustris are difficult to identify. The aim of this study was to simplify species determination in Lucilia larvae for entomological and forensic purposes. Muscle attachment site (MAS) patterns were previously found to be a good tool for species determination in blowfly larvae. Here, distinctive MAS patterns are presented for European Lucilia ampullacea, L. caesar, L. illustris, L. richardsi, L. sericata, and L. silvarum. A joint pattern for the genus Lucilia is provided for a quick classification of a larva to the genus.

  1. Development of a generic, computerized nuclear material accountability system: NucMAS

    International Nuclear Information System (INIS)

    Cornell, M.D.; O'Leary, J.M.

    1987-01-01

    The application NucMAS provides basic computerized accountability functions for the Savannah River Plant (SRP) Separations Department Material Balance Areas (MBA's). These functions include data entry, data management, calculations, and report generation. NucMAS can be used both for routine reporting to the SRP central Material Control and Accounting (MC and A) system and for rapid ad hoc queries in emergency situations. The system is designed to work with any process handling one or more of the 17 accountable nuclear materials specified by the Department of Energy (DOE). It relies on user-supplied configuration data to drive data prompts, report headings, data validations, and calculations

  2. Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.

    Science.gov (United States)

    Pinheiro, Sérgio Veloso Brant; Simões e Silva, Ana Cristina; Sampaio, Walkyria Oliveira; de Paula, Renata Dutra; Mendes, Elizabeth Pereira; Bontempo, Elizabete Dias; Pesquero, João Bosco; Walther, Thomas; Alenina, Natalia; Bader, Michael; Bleich, Markus; Santos, Robson Augusto Souza

    2004-10-01

    It has been described recently that the nonpeptide AVE 0991 (AVE) mimics the effects of angiotensin-(1-7) [Ang-(1-7)] in bovine endothelial cells. In this study, we tested the possibility that AVE is an agonist of the Ang-(1-7) receptor Mas, in vitro and in vivo. In water-loaded C57BL/6 mice, AVE (0.58 nmol/g body weight) produced a significant reduction in urinary volume (0.06+/-0.03 mL/60 min [n=9] versus 0.27+/-0.05 [n=9]; PAVE. As observed previously for Ang-(1-7), the antidiuretic effect of AVE after water load was blunted in Mas-knockout mice (0.37+/-0.10 mL/60 min [n=9] versus 0.27+/-0.03 mL/60 min [n=11] AVE-treated mice). In vitro receptor autoradiography in C57BL/6 mice showed that the specific binding of 125I-Ang-(1-7) to mouse kidney slices was displaced by AVE, whereas no effects were observed in the binding of 125I-angiotensin II or 125I-angiotensin IV. Furthermore, AVE displaced the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells (IC50=4.75x10(-8) mol/L) and of rhodamine-Ang-(1-7) in Mas-transfected Chinese hamster ovary (CHO) cells. It also produced NO release in Mas-transfected CHO cells blocked by A-779 but not by angiotensin II type-1 (AT1) and AT2 antagonists. Contrasting with these data, the antidiuretic effect of AVE was totally blocked by AT2 antagonists and partially blocked (approximately 60%) by AT1 antagonists. The binding data, the results obtained in Mas-knockout mice and in Mas-transfected cells, show that AVE is a Mas receptor agonist. Our data also suggest the involvement of AT2/AT1-related mechanisms, including functional antagonism, oligomerization or cross-talk, in the renal responses to AVE.

  3. 27 Al MAS NMR Studies of HBEA Zeolite at Low to High Magnetic Fields

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jian Z.; Wan, Chuan; Vjunov, Aleksei; Wang, Meng; Zhao, Zhenchao; Hu, Mary Y.; Camaioni, Donald M.; Lercher, Johannes A.

    2017-06-01

    27Al single pulse (SP) MAS NMR spectra of HBEA zeolites with high Si/Al ratios of 71 and 75 were obtained at three magnetic field strengths of 7.05, 11.75 and 19.97 T. High field 27Al MAS NMR spectra acquired at 19.97 T show significantly improved spectral resolution, resulting in at least two well-resolved tetrahedral-Al NMR peaks. Based on the results obtained from 27Al MAS and MQMAS NMR acquired at 19.97 T, four different quadrupole peaks are used to deconvolute the 27Al SP MAS spectra acquired at vari-ous fields by using the same set of quadrupole coupling constants, asymmetric parameters and relative integrated peak intensities for the tetrahedral Al peaks. The line shapes of individual peaks change from typical quadrupole line shape at low field to essentially symmetrical line shapes at high field. We demonstrate that for fully hydrated HBEA zeolites the effect of second order quadrupole interaction can be ignored and quantitative spectral analysis can be performed by directly fitting the high field spectra using mixed Gaussian/Lorentzian line shapes. Also, the analytical steps described in our work allow direct assignment of spectral intensity to individual Al tetrahedral sites (T-sites) of zeolite HBEA. Finally, the proposed concept is suggested generally applicable to other zeo-lite framework types, thus, allowing a direct probing of Al distributions by NMR spectroscopic methods in zeolites with high confi-dence.

  4. Marker-assisted-selection (MAS): A fast track to increase genetic ...

    African Journals Online (AJOL)

    Mapping and tagging of agriculturally important genes have been greatly facilitated by an array of molecular markers in crop plants. Marker-assisted selection (MAS) is gaining considerable importance as it would improve the efficiency of plant breeding through precise transfer of genomic regions of interest (foreground ...

  5. Who bears the burden of international taxation? Evidence from cross-border M&As

    NARCIS (Netherlands)

    Huizinga, H.P.; Voget, J.; Wagner, W.B.

    2012-01-01

    Cross-border M&As can trigger additional taxation of the target's income in the form of non-resident dividend withholding taxes and acquirer-country corporate income taxation. This paper finds that this additional international taxation is fully capitalized into lower takeover premiums. In contrast,

  6. Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma.

    Science.gov (United States)

    Bernardi, Stella; Zennaro, Cristina; Palmisano, Silvia; Velkoska, Elena; Sabato, Nicoletta; Toffoli, Barbara; Giacomel, Greta; Buri, Luigi; Zanconati, Fabrizio; Bellini, Giuseppe; Burrell, Louise M; De Manzini, Nicolò; Fabris, Bruno

    2012-03-01

    A new arm of the renin-angiotensin system (RAS) has been recently characterized; this includes angiotensin converting enzyme (ACE)2 and angiotensin (Ang)1-7, a heptapeptide acting through the Mas receptor (MasR). Recent studies show that Ang1-7 has an antiproliferative action on lung adenocarcinoma cells. The aim of this study was to characterize RAS expression in human colon adenocarcinoma and to investigate whether Ang1-7 exerts an antiproliferative effect on human colon adenocarcinoma cells. Gene, protein expression and enzymatic activity of the main components of the RAS were determined on non-neoplastic colon mucosa as well as on the tumor mass and the mucosa taken 5 cm distant from it, both collected from patients with colon adenocarcinoma. Two different human colon cancer cell lines were treated with AngII and Ang1-7. The novel finding of this study was that MasR was significantly upregulated in colon adenocarcinoma compared with non-neoplastic colon mucosa, which showed little or no expression of it. ACE gene expression and enzymatic activity were also increased in the tumors. However, AngII and Ang1-7 did not have any pro-/antiproliferative effects in the cell lines studied. The data suggest that upregulation of the MasR could be used as a diagnostic marker of colon adenocarcinoma.

  7. 29Si MAS NMR for the zeolite Y - gallium oxide system

    International Nuclear Information System (INIS)

    Sulikowski, B.; Derewinski, M.; Olejniczak, Z.; Segnowski, S.

    1994-01-01

    Wide-pore zeolites modified by gallium oxide has been prepared for catalytic use. Its physico-chemical and catalytic properties have been studied. The structure changes of the catalyst have been investigated by means of MAS NMR spectroscopy. Spectra of 29 Si has been described and discussed

  8. An Analysis of the Rise and Fall of the AA-MAS Policy

    Science.gov (United States)

    Lazarus, Sheryl S.; Thurlow, Martha L.; Ysseldyke, James E.; Edwards, Lynn M.

    2015-01-01

    In 2005, to address concerns about students who might fall in the "gap" between the regular assessment and the alternate assessment based on alternate achievement standards (AA-AAS), the U.S. Department of Education announced that states could develop alternate assessments based on modified achievement standards (AA-MAS). This article…

  9. Successfully Transitioning from the AA-MAS to the General Assessment. NCEO Policy Directions. Number 22

    Science.gov (United States)

    Lazarus, Sheryl; Thurlow, Martha; Christensen, Laurene; Shyyan, Vitaliy

    2014-01-01

    Federal policy initiatives such as the flexibility waivers for accountability are requiring that states transition away from the use of an alternate assessment based on modified achievement standards (AA-MAS). It is expected that those students who had participated in that assessment will instead participate in the state's general assessment (or a…

  10. Considerations for Consortia as States Transition Away from AA-MAS. NCEO Brief. Number 7

    Science.gov (United States)

    National Center on Educational Outcomes, 2014

    2014-01-01

    States with an alternate assessment based on modified achievement standards (AA-MAS) that received a flexibility waiver from some of the requirements of No Child Left Behind are required to phase out their use of this assessment. And, on August 23, 2013, the U.S. Department of Education published a proposed rollback of regulation that allowed the…

  11. Application of HR-MAS NMR spectroscopy for studying chemotype variations of Withania somnifera (L.) Dunal.

    Science.gov (United States)

    Bharti, S K; Bhatia, Anil; Tewari, S K; Sidhu, O P; Roy, Raja

    2011-10-01

    Withania somnifera (L.) Dunal (Solanaceae), commonly known as Ashwagandha, is one of the most valued Indian medicinal plants with a number of pharmaceutical and nutraceutical applications. Metabolic profiling has been performed by HR-MAS NMR spectroscopy on fresh leaf and root tissue specimens from four chemotypes of W. somnifera. The HR-MAS NMR spectroscopy of lyophilized defatted leaf tissue specimens clearly distinguishes resonances of medicinally important secondary metabolites (withaferin A and withanone) and its distinctive quantitative variability among the chemotypes. A total of 41 metabolites were identified from both the leaf and root tissues of the chemotypes. The presence of methanol in leaf and root tissues of W. somnifera was detected by HR-MAS NMR spectroscopy. Multivariate principal component analysis (PCA) on HR-MAS (1) H NMR spectra of leaves revealed clear variations in primary metabolites among the chemotypes. The results of the present study demonstrated an efficient method, which can be utilized for metabolite profiling of primary and secondary metabolites in medicinally important plants. Copyright © 2011 John Wiley & Sons, Ltd.

  12. Two-Stage MAS Technique for Analysis of DRA Elements and Arrays on Finite Ground Planes

    DEFF Research Database (Denmark)

    Larsen, Niels Vesterdal; Breinbjerg, Olav

    2007-01-01

    A two-stage Method of Auxiliary Sources (MAS) technique is proposed for analysis of dielectric resonator antenna (DRA) elements and arrays on finite ground planes (FGPs). The problem is solved by first analysing the DRA on an infinite ground plane (IGP) and then using this solution to model the FGP...

  13. Factor analysis of 27Al MAS NMR spectra for identifying nanocrystalline phases in amorphous geopolymers

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Martina; Kobera, Libor; Brus, Jiří

    2013-01-01

    Roč. 51, č. 11 (2013), s. 734-742 ISSN 0749-1581 R&D Projects: GA ČR(CZ) GA13-24155S Institutional support: RVO:61389013 Keywords : solid-state NMR * 27Al MAS NMR * factor analysis Subject RIV: JN - Civil Engineering Impact factor: 1.559, year: 2013

  14. Acceptance Test Report for the Modular Automation System (MAS) Manufactured by Honeywell Inc.

    Energy Technology Data Exchange (ETDEWEB)

    ANDERSON, D.L.

    2000-02-01

    This document details the performance of the acceptance test of the Honeywell MAS Control System for equipment to be installed in gloveboxes HA-20MB and HA-211 at a later date. Equipment that was anticipated included 6 stabilization furnaces, only three and their associated equipment were installed.

  15. HUBUNGAN ANTARA PERTUMBUHAN DENGAN KEBERADAAN GEN TAHAN PENYAKIT MAJOR HISTOCOMPATIBILITY COMPLEX (MHC PADA IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Erma Primanita Hayuningtyas

    2016-04-01

    Full Text Available Wabah penyakit koi herpes virus (KHV di Indonesia yang terjadi sejak tahun 2002 merupakan salah satu faktor yang memicu kemerosotan produksi ikan mas budidaya. Pembentukan strain unggul ikan mas tahan KHV dapat menjadi solusi bagi permasalahan tersebut. Pemilihan genotip ikan mas tahan KHV dengan marka molekuler gen major histocompatibility complex class II (MHC-II, khususnya pada alel Cyca DAB 1*05 akan membantu dalam kegiatan seleksi. Penelitian ini bertujuan untuk mengetahui keberadaan gen MHC-II pada populasi dasar G0 ikan mas strain Rajadanu dan hubungannya dengan pertumbuhan (bobot. Metode deteksi keberadaan gen MHC-II pada dua kelompok ikan dengan ukuran berbeda dilakukan dengan teknik PCR. Hubungan antara pertumbuhan ikan mas dengan persentase kemunculan gen MHC-II dianalisis dengan menggunakan program SPSS (Statistical Package for the Social Sciences, sehingga diperoleh korelasi di antara keduanya. Hasil penelitian menunjukkan bahwa hubungan antara pertumbuhan dengan persentase keberadaan gen MHC-II berkorelasi negatif dengan nilai R = -0,742. Hal ini mengindikasikan bahwa semakin cepat pertumbuhan populasi ikan mas maka semakin sedikit persentase individu yang mempunyai gen MHC-II pada setiap populasi ikan mas. Sehingga populasi ikan mas yang pertumbuhannya lambat memiliki tingkat persentase positif MHC-II lebih tinggi (85,71%-100% dibandingkan populasi ikan mas yang pertumbuhannya cepat (42,86%-85,71%.

  16. Hyperspectral Microwave Atmospheric Sounder (HyMAS) architecture and design accommodations

    Science.gov (United States)

    Hilliard, L.; Racette, P.; Blackwell, W.; Galbraith, C.; Thompson, E.

    The Hyperspectral Microwave Atmospheric Sounder (HyMAS) is being developed at Lincoln Laboratories and accommodated by the Goddard Space Flight Center for a flight opportunity on a NASA research aircraft. The term “ hyperspectral microwave” is used to indicate an all-weather sounding that performs equivalent to hyperspectral infrared sounders in clear air with vertical resolution of approximately 1 km. Deploying the HyMAS equipped scanhead with the existing Conical Scanning Microwave Imaging Radiometer (CoSMIR) shortens the path to a flight demonstration. Hyperspectral microwave is achieved through the use of independent RF antennas that sample the volume of the Earth's atmosphere through various levels of frequencies, thereby producing a set of dense, spaced vertical weighting functions. The simulations proposed for HyMAS 118/183-GHz system should yield surface precipitation rate and water path retrievals for small hail, soft hail, or snow pellets, snow, rainwater, etc. with accuracies comparable to those of the Advanced Technology Microwave Sounder. Further improvements in retrieval methodology (for example, polarization exploitation) are expected. The CoSMIR instrument is a packaging concept re-used on HyMAS to ease the integration features of the scanhead. The HyMAS scanhead will include an ultra-compact Intermediate Frequency Processor (IFP) module that is mounted inside the door to improve thermal management. The IFP is fabricated with materials made of Low-Temperature Co-fired Ceramic (LTCC) technology integrated with detectors, amplifiers, A/D conversion and data aggregation. The IFP will put out 52 channels of 16 bit data comprised of 4 - 9 channel data streams for temperature profiles and 2-8 channel streams for water vapor. With the limited volume of the existing CoSMIR scanhead and new HyMAS front end components, the HyMAS team at Goddard began preliminary layout work inside the new drum. Importing and re-using models of the shell, the s- an head

  17. Angiotensin-(1-7 attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

    Directory of Open Access Journals (Sweden)

    María Gabriela Morales

    2016-04-01

    Full Text Available Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angiotensin system (RAS causes deleterious effects in skeletal muscle, including muscle wasting. In contrast, angiotensin-(1-7 [Ang-(1-7], a peptide of the non-classical RAS, produces beneficial effects in skeletal muscle. However, the role of Ang-(1-7 in skeletal muscle disuse atrophy and independent of classical RAS activation has not been evaluated. Therefore, we assessed the functions of Ang-(1-7 and the Mas receptor in disuse muscle atrophy in vivo using unilateral cast immobilization of the hind limb in male, 12-week-old wild-type (WT and Mas-knockout (Mas KO mice for 1 and 14 days. Additionally, we evaluated the participation of IGF-1/IGFR-1/Akt signalling and ubiquitin-proteasome pathway expression on the effects of Ang-(1-7 immobilization-induced muscle atrophy. Our results found that Ang-(1-7 prevented decreased muscle strength and reduced myofiber diameter, myosin heavy chain levels, and the induction of atrogin-1 and MuRF-1 expressions, all of which normally occur during immobilization. Analyses indicated that Ang-(1-7 increases IGF-1/IGFR-1/Akt pathway signalling through IGFR-1 and Akt phosphorylation, and the concomitant activation of two downstream targets of Akt, p70S6K and FoxO3. These anti-atrophic effects of Ang-(1-7 were not observed in Mas KO mice, indicating crucial participation of the Mas receptor. This report is the first to propose anti-atrophic effects of Ang-(1-7 via the Mas receptor and the participation of the IGF-1/IGFR-1/Akt/p70S6K/FoxO3 mechanism in disuse skeletal muscle atrophy.

  18. Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

    Science.gov (United States)

    Morales, María Gabriela; Abrigo, Johanna; Acuña, María José; Santos, Robson A.; Bader, Michael; Brandan, Enrique; Simon, Felipe; Olguin, Hugo; Cabrera, Daniel; Cabello-Verrugio, Claudio

    2016-01-01

    ABSTRACT Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angiotensin system (RAS) causes deleterious effects in skeletal muscle, including muscle wasting. In contrast, angiotensin-(1-7) [Ang-(1-7)], a peptide of the non-classical RAS, produces beneficial effects in skeletal muscle. However, the role of Ang-(1-7) in skeletal muscle disuse atrophy and independent of classical RAS activation has not been evaluated. Therefore, we assessed the functions of Ang-(1-7) and the Mas receptor in disuse muscle atrophy in vivo using unilateral cast immobilization of the hind limb in male, 12-week-old wild-type (WT) and Mas-knockout (Mas KO) mice for 1 and 14 days. Additionally, we evaluated the participation of IGF-1/IGFR-1/Akt signalling and ubiquitin-proteasome pathway expression on the effects of Ang-(1-7) immobilization-induced muscle atrophy. Our results found that Ang-(1-7) prevented decreased muscle strength and reduced myofiber diameter, myosin heavy chain levels, and the induction of atrogin-1 and MuRF-1 expressions, all of which normally occur during immobilization. Analyses indicated that Ang-(1-7) increases IGF-1/IGFR-1/Akt pathway signalling through IGFR-1 and Akt phosphorylation, and the concomitant activation of two downstream targets of Akt, p70S6K and FoxO3. These anti-atrophic effects of Ang-(1-7) were not observed in Mas KO mice, indicating crucial participation of the Mas receptor. This report is the first to propose anti-atrophic effects of Ang-(1-7) via the Mas receptor and the participation of the IGF-1/IGFR-1/Akt/p70S6K/FoxO3 mechanism in disuse skeletal muscle atrophy. PMID:26851244

  19. Comparison of the 1H NMR analysis of solids by the CRAMPS and MAS-only techniques

    Science.gov (United States)

    Dec, Steven F.; Bronnimann, Charles E.; Wind, Robert A.; Maciel, Gary E.

    1H NMR spectra are reported on eight representative solid samples, including pure powdered crystalline samples, synthetic organic polymers, a silica gel, HY zeolite, and a lignite. Spectra were obtained by the following three approaches: (1) single pulse on a static sample, (2) CRAMPS, and (3) single pulse with magic-angle spinning (MAS-only). The MAS-only results were obtained as a function of MAS speed. Although the MAS-only technique is capable of achieving a significant degree of line narrowing, even with modest MAS speeds, MAS-only spectra of the general quality of the apparently undistorted high-resolution 1H spectra obtained by the CRAMPS technique are not obtained at the highest MAS speeds examined (21 kHz for a polymethylmethacrylate sample), unless the 1H- 1H dipolar interactions in the sample are rather weak, as with silica gel or a zeolite. Thus, caution should be exercised in interpreting 1H MAS-only spectra, especially if CRAMPS results are not available as a calibration.

  20. Participation and Performance Reporting for the Alternate Assessment Based on Modified Achievement Standards (AA-MAS). Technical Report 58

    Science.gov (United States)

    Albus, Deb; Thurlow, Martha L.; Lazarus, Sheryl S.

    2011-01-01

    This report examines publicly reported participation and performance data for the alternate assessment based on modified achievement standards (AA-MAS). The authors' analysis of these data included all states publicly reporting AA-MAS data, regardless of whether they had received approval to use the results for Title I accountability calculations.…

  1. A hybrid MAS/MoM technique for 2D impedance scatterers illuminated by closely positioned sources

    DEFF Research Database (Denmark)

    Larsen, Niels Vesterdal; Breinbjerg, Olav

    2005-01-01

    A hybrid technique for 2D scattering problems with impedance structures and closely positioned illuminating sources is presented. This technique combines the method of auxiliary sources (MAS) with a localized method of moments (MoM) region near the source. Significant improvements over standard MAS...

  2. El Proyecto Sismico "LARSE" - Trabajando Hacia un Futuro con Mas Seguridad para Los Angeles

    Science.gov (United States)

    Henyey, Thomas L.; Fuis, Gary S.; Benthien, Mark L.; Burdette, Thomas R.; Christofferson, Shari A.; Clayton, Robert W.; Criley, Edward E.; Davis, Paul M.; Hendley, James W.; Kohler, Monica D.; Lutter, William J.; McRaney, John K.; Murphy, Janice M.; Okaya, David A.; Ryberg, Trond; Simila, Gerald W.; Stauffer, Peter H.

    1999-01-01

    La region de Los Angeles contiene una red de fallas activas, incluyendo muchas fallas por empuje que son profundas y no rompen la superficie de la tierra. Estas fallas ocultas incluyen la falla anteriormente desconocida que fue responsable por la devastacion que ocurrio durante el terremoto de Northridge en enero de 1994, el terremoto mas costoso en la historia de los Estados Unidos. El Experimento Sismico en la Region de Los Angeles (Los Angeles Region Seismic Experiment, LARSE), esta localizando los peligros ocultos de los terremotos debajo de la region de Los Angeles para mejorar la construccion de las estructuras que pueden apoyar terremotos que son inevitables en el futuro, y que ayudaran a los cientificos determinar donde occurira el sacudimento mas fuerte y poderoso.

  3. Porfirio Díaz en la historiografía masónica mexicana

    Directory of Open Access Journals (Sweden)

    Marco Antonio Flores Zavala

    2015-01-01

    Full Text Available En este artículo se analiza la presencia del general Porfirio Díaz en la historiografía masónica mexicana. Parala redacción de este texto se recurrió a las obras de José María Mateos (Historia de la masonería en Méxicodesde 1806 hasta 1884, Richard Chism (Una contribución a la historia masónica de México y Luis J. Zalce(Apuntes para la historia de la masonería en México, de mis lecturas y mis recuerdos. El cuestionario esbásico: ¿Qué fuentes documentales utilizaron los autores para redactar sus textos? ¿Cómo examinan laactuación del general Díaz, como actor de un régimen o un hermano masón? Pese a lo elemental de laspreguntas, éstas colaboran para situar parte de los tópicos y de las formas en que fueron redactadas lashistorias de la masonería en México. El artículo está integrado con dos secciones. En la primera se esboza unabiografía del general Díaz y se presentan las obras que se definen como historiografía masónica mexicana. Lasegunda sección presenta la descripción de las obras y cómo examinaron la presencia de Díaz en lamasonería.

  4. The Influence of Store Atmosphere on Consumer Purchase Decision at Kawan Baru Restaurant Mega Mas Manado

    OpenAIRE

    Waloejan, Nia Anggreini

    2016-01-01

    Culinary business is a business type that€™s growing rapidly in the city of Manado. Nowadays, a taste of food, price, services and quality of the foods no longer being a major consideration for the culinary connoisseur. The store atmosphere becomes an important factor for consumers to choosing a place for dine. The research aim to analyzing the influence of store atmosphere on Kawan Baru Restaurant Mega Mas Manado. The analytical methods of analysis used by multiple linear regression analysi...

  5. HR MAS 1H NMR spectroscopy analysis of marine microalgal whole cells

    OpenAIRE

    Chauton, Matilde S.; Optun, Odd Inge; Bathen, Tone F.; Volent, Zsolt; Gribbestad, Ingrid S.; Johnsen, Geir

    2003-01-01

    To study the use of nuclear magnetic resonance (NMR) spectroscopy as a method of classification, we performed high-resolution magic angle spinning proton (HR MAS 1H) NMR spectroscopy analysis of whole-cell samples of Dunaliella sp. (Chlorophyceae), Amphidinium carterae (Dinophyceae), Phaeodactylum tricornutum and Thalassiosira pseudonana (Bacillariophyceae). Emphasising the potential use of NMR spectroscopy as a routine analysis of microalgae we chose a straightforward procedure for culturing...

  6. Ammonia Vapor Removal by Cu3(BTC)2 and Its Characterization by MAS NMR

    OpenAIRE

    Peterson, Gregory W.; Wagner, George W.; Balboa, Alex; Mahle, John; Sewell, Tara; Karwacki, Christopher J.

    2009-01-01

    Adsorption equilibria and NMR experiments were performed to study the adsorption and interactions of ammonia with metal-organic framework (MOF) HKUST-1, or Cu3(BTC)2 (BTC = 1,3,5-benzenetricarboxylate). Ammonia capacities determined from chemical breakthrough measurements show significantly higher uptake capacities than from adsorption alone, suggesting a stronger interaction involving a potential reaction with the Cu3(BTC)2 framework. Indeed, 1H MAS NMR reveals that a major disruption of the...

  7. Analisa Internal dan Eksternal pada CV. Gading Mas Surya Sidoarjo dalam Rangka Strategi Bersaing

    OpenAIRE

    Lesal, Indriani

    2015-01-01

    Strategi merupakan faktor internal yang penting untuk dipertimbangkan dalam perencanaan dan pengambilan keputusan. Setiap Perusahaan, baik yang bergerak di bidang jasa maupun non jasa, dalam melakukan kegiatan bisnis memerlukan strategi yang mampu menempatkan Perusahaan pada posisi yang terbaik, mampu bersaing serta terus berkembang dengan mengoptimalkan semua potensi sumber daya yang dimiliki. Tujuan penelitian ini adalah merumuskan strategi bersaing yang sesuai digunakan oleh CV. Gading Mas...

  8. Fusion of Multi-Vision of Industrial Robot in MAS-Based Smart Space

    Directory of Open Access Journals (Sweden)

    Li Hexi

    2015-01-01

    Full Text Available The paper presents a fusion method of muti-vision of industrial robot in a smart space based on multi-agent system(MAS, the robotic multi-vision consists of top-view, side-view, front-view and hand-eye cameras, the moving hand-eye provide vision guidance and give the estimation of robot position, other three cameras are used for target recognition and positioning. Each camera is connected to an agent based on an image-processing computer that aims at analyzing image rapidly and satisfying the real-time requirement of data processing. As a learning strategy of robotic vision, a back-propagation neural network(BPNN with 3-layer-architecture is first constructed for each agent and is independently trained as a classifier of target recognition using batch gradient descent method based on the region features extracted from the images of target samples(typical mechanical parts, and then the outputs of trained BPNNs in MAS-based smart space are fused with Dempster-Shafer evidence theory to form a final recognition decision, the experimental results of typical mechanical parts show that fusion of multi-vision can improve the robotic vision accuracy and MAS-based smart space will contribute to the parallel processing of immense image data in robotic multi-vision system.

  9. Magnetic-Field-Gradient-Coil System for Solid-State MAS and Cramps NMR Imaging

    Science.gov (United States)

    Buszko, M.; Maciel, G. E.

    The idea of combining cylindrical coils for producing a longitudinal gradient with respect to the MAS axis with quadrupole (straight wire) magnetic-field-gradient coils for producing two transverse gradients for 3D MAS and CRAMPS imaging has been demonstrated. A modified set of a double Maxwell pair and two sets of quadrupole (eight-wire) coils were combined in a compact way and adapted for a 5 mm MAS rotor, achieving gradients of high efficiency (4.3 and 2.9 G/cm A for longitudinal and transverse coils, respectively), low inductance (3.5 and 1.9 μH, respectively), and very good linearity(1%). A 60 μm spatial resolution in a TREV-CRAMPS imaging experiment on solid polyethylene oxide was demonstrated; gradient pulses of 12 μs duration were generated by applying currents of 2.3 and 1.5 A to longitudinal and transverse coils, respectively. This magnetic-field-gradient-coil configuration could also be applied in other areas of NMR where time-dependent gradients are required.

  10. Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics.

    Science.gov (United States)

    Austdal, Marie; Thomsen, Liv Cecilie Vestrheim; Tangerås, Line Haugstad; Skei, Bente; Mathew, Seema; Bjørge, Line; Austgulen, Rigmor; Bathen, Tone Frost; Iversen, Ann-Charlotte

    2015-12-01

    Preeclampsia is a heterogeneous gestational disease characterized by maternal hypertension and proteinuria, affecting 2-7% of pregnancies. The disorder is initiated by insufficient placental development, but studies characterizing the placental disease components are lacking. Our aim was to phenotype the preeclamptic placenta using high-resolution magic angle spinning nuclear magnetic resonance spectroscopy (HR-MAS MRS). Placental samples collected after delivery from women with preeclampsia (n = 19) and normotensive pregnancies (n = 15) were analyzed for metabolic biomarkers including amino acids, osmolytes, and components of the energy and phospholipid metabolism. The metabolic biomarkers were correlated to clinical characteristics and inflammatory biomarkers in the maternal sera. Principal component analysis showed inherent differences in placental metabolic profiles between preeclamptic and normotensive pregnancies. Significant differences in metabolic profiles were found between placentas from severe and non-severe preeclampsia, but not between preeclamptic pregnancies with fetal growth restricted versus normal weight neonates. The placental metabolites correlated with the placental stress marker sFlt-1 and triglycerides in maternal serum, suggesting variation in placental stress signaling between different placental phenotypes. HR-MAS MRS is a sensitive method for defining the placental disease component of preeclampsia, identifying several altered metabolic pathways. Placental HR-MAS MRS analysis may improve insight into processes affected in the preeclamptic placenta, and represents a novel long-required tool for a sensitive placental phenotyping of this heterogeneous disease. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. UPLC-TOF-MS Characterization and Identification of Bioactive Iridoids in Cornus mas Fruit

    Directory of Open Access Journals (Sweden)

    Shixin Deng

    2013-01-01

    Full Text Available Cornus mas L. is indigenous to Europe and parts of Asia. Although Cornus is widely considered to be an iridoid rich genera, only two iridoids have been previously found in this plant. The lack of information on taxonomically and biologically active iridoids prompted us to develop and optimize an analytical method for characterization of additional phytochemicals in C. mas fruit. An ultra performance liquid chromatography (UPLC coupled with photodiode array spectrophotometry (PDA and electrospray time-of-flight mass spectrometry (ESI-TOF-MS was employed and mass parameters were optimized. Identification was made by elucidating the mass spectral data and further confirmed by comparing retention times and UV spectra of target peaks with those of reference compounds. Primary DNA damage and antigenotoxicity tests in E. coli PQ37 were used to screen the iridoids for biological activity. As a result, ten phytochemicals were identified, including iridoids loganic acid, loganin, sweroside, and cornuside. Nine of these were reported for the first time from C. mas fruit. The iridoids did not induce SOS repair of DNA, indicating a lack of genotoxic activity in E. coli PQ37. However, loganin, sweroside, and cornuside did reduce the amount of DNA damage caused by 4-nitroquinoline 1-oxide, suggesting potential antigenotoxic activity.

  12. Stanowisko badawcze do oceny efektów utwardzania mas ze szkłem wodnym

    Directory of Open Access Journals (Sweden)

    M. Stachowicz

    2012-12-01

    Full Text Available W pracy przedstawiono wyniki badań nad możliwością zastosowania nowego stanowiska badawczego do oceny, na podstawie końcowejzawartości wody, finalnego efektu utwardzania wybranymi metodami mas ze szkłem wodnym. Badania wykonano na innowacyjnym,mobilnym stanowisku mikrofalowej linii szczelinowej wykorzystującej zjawisko występowania fali stojącej w falowodzie. Badaniompoddano pięć mas sporządzonych z dostępnymi w handlu gatunkami szkła wodnego, które utwardzano trzema, wybranymi metodami:mikrofalową, klasyczną oraz w procesie CO2. Wykazano, na przykładzie mas ze szkłem wodnym, że prezentowane, mobilne stanowiskopomiarowe może, na podstawie określenia końcowej zawartości wody, służyć z powodzeniem do oceny ostatecznego efektu utwardzaniamas formierskich i rdzeniowych.

  13. Pengaruh Penyimpanan Atmosfer Termodifikasi (Modified Atmosphere Storage/ MAS terhadap Karakteristik Jamur Tiram Putih (Pleurotus ostreatus

    Directory of Open Access Journals (Sweden)

    Bambang Susilo

    2017-02-01

    Full Text Available The food storing technology is growing fast. Since the optimal storage could increase the value of the material being stored. A proposed solution to overcome counter this issue is the use of modified atmosphere storage (MAS technology. White oyster mushroom (Pleurotus ostreatus is one of vegetables that is highly perishable that makes this mushroom has a short shelf life. Therefore, appropriate postharvest handling is needed to maintain the quality of oyster mushrooms by expanding its shelf life. The aims of this research were to assess the effect of the use of MAS technology and to characterize the white oyster mushroom. Based on the research conducted at the Laboratory of Agricultural Processing and Postharvest Engineering, Department of Agricultural Engineering, Brawijaya University showed that the modified atmosphere storage of white oyster mushroom affected the respiration rate and shelf life of the studied commodities. On the basis of the observations on each parameter (respiration rate and storage time, the normal storage time for white oyster mushrooms is 1 day. While iby applying MAS, the white oyster mushrooms could last for 3 days using treatment A (21 % O and B (12,4 – 12,5 %   O, and could last for 4 days using treatment C (9,2– 9,3 % O2 , D (5,9 – 6,1 % O2, and E (3,5 – 3,7 % O. Therefore, It can be concluded that by using MAS storage at low O2 concentrations, the shelf life of mushrooms could be longer. ABSTRAK Teknologi penyimpanan saat ini berkembang cukup pesat. Hal ini dikarenakan penyimpanan yang optimal akan meningkatkan nilai dari bahan yang disimpan. Salah satu upaya yang dapat dilakukan untuk hal tersebut yaitu penyimpanan menggunakan metode atmosfer termodifikasi (Modified Atmosphere Storage/MAS. Jamur tiram putih (Pleurotus ostreatus merupakan salah satu komoditas sayuran yang bersifat mudah rusak, hal ini membuat jenis jamur ini memiliki umur simpan yang terbilang singkat. Oleh karena itu, penanganan pasca

  14. Dose reduction in dynamic CT stress myocardial perfusion imaging: comparison of 80-kV/370-mAs and 100-kV/300-mAs protocols.

    Science.gov (United States)

    Fujita, Makiko; Kitagawa, Kakuya; Ito, Tatsuro; Shiraishi, Yasuyuki; Kurobe, Yusuke; Nagata, Motonori; Ishida, Masaki; Sakuma, Hajime

    2014-03-01

    To determine the effect of reduced 80-kV tube voltage with increased 370-mAs tube current on radiation dose, image quality and estimated myocardial blood flow (MBF) of dynamic CT stress myocardial perfusion imaging (CTP) in patients with a normal body mass index (BMI) compared with a 100-kV and 300-mAs protocol. Thirty patients with a normal BMI (stress dual-source dynamic CTP. Patients were randomised to 80-kV/370-mAs (n = 15) or 100-kV/300-mAs (n = 15) imaging. Maximal enhancement and noise of the left ventricular (LV) cavity, contrast-to-noise ratio (CNR) and MBF of the two groups were compared. Imaging with 80-kV/370-mAs instead of 100-kV/300-mAs was associated with 40% lower radiation dose (mean dose-length product, 359 ± 66 vs 628 ± 112 mGy[Symbol: see text]cm; P noise (22.7 ± 3.5 vs 17.4 ± 2.6; P stress perfusion imaging (CTP) is increasingly used to assess myocardial function. • Dynamic CTP is feasible at 80-kV in patients with normal BMI. • An 80-kV/370-mAs protocol allows 40% dose reduction compared with 100-kV/300-mAs. • Contrast-to-noise ratio and myocardial blood flow of the two protocols were comparable.

  15. TOKSISITAS SUBLETAL MOLUSKISIDA NIKLOSAMIDA TERHADAP PERTUMBUHAN DAN KONDISI HEMATOLOGI YUWANA IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Yosmaniar Yosmaniar

    2016-11-01

    Full Text Available Niklosamida digunakan secara intensif sebagai pestisida di sawah untuk membunuh keong mas (Pomacea sp.. Tujuan penelitian ini adalah untuk menentukan pengaruh toksisitas subletal moluskisida niklosamida terhadap pertumbuhan dan kondisi hematologi yuwana ikan mas (Cyprinus carpio. Penelitian dilakukan di Instalasi Riset Lingkungan Perikanan Budidaya dan Toksikologi Cibalagung Balai Riset Perikanan Budidaya Air Tawar Bogor. Penelitian menggunakan rancangan acak lengkap dengan 4 perlakuan dan 4 ulangan. Waktu penelitian 12 minggu. Perlakuan adalah konsentrasi moluskisida niklosamida, yaitu: 0,00 (kontrol; 0,01; 0,03; dan 0,05 mg/L. Menggunakan 16 akuarium ukuran 70 cm x 50 cm x 60 cm. Benih ikan mas yang digunakan berkisar 2,5-3,0 gram dipelihara dengan kepadatan 20 ekor dalam volume air 40 L. Selama pemaparan ikan uji diberi pakan secara at satiation serta dilakukan pergantian air setiap 48 jam dengan konsentrasi bahan uji yang sama. Peubah yang diukur adalah laju pertumbuhan dan kondisi hematologi. Hasil penelitian menunjukkan bahwa konsentrasi subletal moluskisida niklosamida berpengaruh nyata terhadap penurunan pertumbuhan terjadi mulai pada konsentrasi 0,03 mg/L sedangkan terhadap kondisi hematologi, yaitu peningkatan hematokrit dan hemoglobin pada konsentrasi 0,01 mg/L dan peningkatan jumlah eritrosit pada konsentrasi 0,03 mg/L, dan penurunan leukosit pada konsentrasi 0,03 mg/L. Niklosamida digunakan secara intensif sebagai pestisida di sawah untuk membunuh keong mas (Pomacea sp.. Tujuan penelitian ini adalah untuk menentukan pengaruh toksisitas subletal moluskisida niklosamida terhadap pertumbuhan dan kondisi hematologi yuwana ikan mas (Cyprinus carpio. Penelitian dilakukan di Instalasi Riset Lingkungan Perikanan Budidaya dan Toksikologi Cibalagung Balai Riset Perikanan Budidaya Air Tawar Bogor. Penelitian menggunakan rancangan acak lengkap dengan 4 perlakuan dan 4 ulangan. Waktu penelitian 12 minggu. Perlakuan adalah konsentrasi moluskisida

  16. Muscle attachment site (MAS) patterns for species determination in five species of Sarcophaga (Diptera: Sarcophagidae).

    Science.gov (United States)

    Niederegger, Senta; Szpila, Krzysztof; Mall, Gita

    2016-01-01

    To further establish species determination using the muscle attachment site (MAS) pattern method, third instar larvae of five forensically important species of Sarcophaga Meigen were investigated: Sarcophaga argyrostoma (Robineau-Desvoidy), Sarcophaga caerulescens Zetterstedt, Sarcophaga melanura Meigen, Sarcophaga albiceps Meigen and Sarcophaga similis Meade. As in the previously investigated Calliphoridae, patterns were found to be species specific. The main feature of the Sarcophaga patterns is the divided central horizontal row of segment four. A genus pattern was established to be used as base for comparison in further species determination.

  17. Recent Results from the MicroMAS Global Environmental MonitoringNanosatellite Mission

    Science.gov (United States)

    Blackwell, W. J.; Cahoy, K.

    2014-12-01

    The Micro-sized Microwave Atmospheric Satellite (MicroMAS) is a dual-spinning 3U CubeSat equipped with apassive microwave radiometer that observes in nine channels near the 118.75-GHz oxygen absorption line.MicroMAS is designed to observe convective thunderstorms, tropical cyclones, and hurricanes from a midinclinationorbit. The MicroMAS flight unit was developed by MIT Lincoln Laboratory and the MIT Space SystemsLaboratory and was launched to the International Space Station on July 13, 2014, and scheduled for an earlySeptember deployment for a ~90-day mission. The payload is housed in the "lower" 1U of the dual-spinning 3UCubeSat and mechanically rotated approximately once per second as the spacecraft orbits the Earth, resulting in across-track scanned beam with a full-width half-max (FWHM) beamwidth of 2.4 degrees and an approximately 17-km diameter footprint at nadir incidence from a nominal altitude of 400 km. The relatively low cost of MicroMASenables the deployment of a constellation of sensors, spaced equally around several orbit planes. A small fleet ofMicroMAS systems could yield high-resolution global temperature and water vapor profiles, as well as cloudmicrophysical and precipitation parameters.Significant advancements were made in the Assembly, Integration, and Test phase of the project developmentlifecycle. The flight software and communications architecture was refined and tested in relevant lab facilities. Thepower subsystem was modified to include additional required inhibits for the ISS launch. Hardware in the loop testsas well as simulations of the attitude determination and control system (ADCS) were performed to validate theunique dual-spinning, local vertical, local horizontal (LVLH) stabilized flight design. ADCS algorithms were testedon a 3-axis air bearing and custom rig inside a 3-axis programmable Helmholtz cage. Finally, the integratedspacecraft underwent a series of environmental tests in order to verify the results of thermal modeling

  18. MAS: Malware Analysis System Based on Hardware-Assisted Virtualization Technology

    Science.gov (United States)

    Kim, Taehyoung; Kim, Inhyuk; Min, Changwoo; Eom, Young Ik

    There are many analysis techniques in order to analyze malicious codes. However, recently malicious codes often evade detection using stealthy obfuscation techniques, and attack computing systems. We propose an enhanced dynamic binary instrumentation using hardware-assisted virtualization technology. As a machine-level analyzer, our system can be isolated from almost the whole threats of malware, and provides single step analysis environment. Proposed system also supports rapid system call analysis environment. We implement our malware analysis system (referred as MAS) on the KVM hypervisor with Intel VT-x virtualization support. Our experiments with benchmarks show that the proposed system provides efficient analysis environment with low overhead.

  19. MODIS Airborne Simulator (MAS) Measurements Taken Onboard the NASAER-2 During the TOGA COARE Intensive Observing Period

    Data.gov (United States)

    National Aeronautics and Space Administration — The TOGA COARE Data Information System has responsibility for distributing information about TOGA COAREdatasets and access paths.The MAS data are available upon...

  20. Exposure (mAs) optimisation of a multi-detector CT protocol for hepatic lesion detection: are thinner slices better?

    International Nuclear Information System (INIS)

    Dobeli, Karen L.; Lewis, Sarah J.; Meikle, Steven R.; Brennan, Patrick C.; Thiele, David L.

    2014-01-01

    The purpose of this work was to determine the exposure-optimised slice thickness for hepatic lesion detection with CT. A phantom containing spheres (diameter 9.5, 4.8 and 2.4mm) with CT density 10 HU below the background (50 HU) was scanned at 125, 100, 75 and 50 mAs. Data were reconstructed at 5-, 3- and 1-mm slice thicknesses. Noise, contrast-to-noise ratio (CNR), area under the curve (AUC) as calculated using receiver operating characteristic analysis and sensitivity representing lesion detection were calculated and compared. Compared with the 125 mAs/5mm slice thickness setting, significant reductions in AUC were found for 75 mAs (P<0.01) and 50 mAs (P<0.05) at 1- and 3-mm thicknesses, respectively; sensitivity for the 9.5-mm sphere was significantly reduced for 75 (P<0.05) and 50 mAs (P<0.01) at 1-mm thickness; sensitivity for the 4.8-mm sphere was significantly lower for 100, 75 and 50 mAs at all three slice thicknesses (P<0.05). The 2.4-mm sphere was rarely detected. At each slice thickness, noise at 100, 75 and 50 mAs exposures was approximately 10, 30 and 50% higher, respectively, than that at 125 mAs exposure. CNRs decreased in an irregular manner with reductions in exposure and slice thickness. This study demonstrated no advantage to using slices below 5mm thickness, and consequently thinner slices are not necessarily better.

  1. 1H HR-MAS NMR and S180 cells: metabolite assignment and evaluation of pulse sequence

    International Nuclear Information System (INIS)

    Oliveira, Aline L. de; Martinelli, Bruno César B.; Lião, Luciano M.; Pereira, Flávia C.; Silveira-Lacerda, Elisangela P.; Alcantara, Glaucia B.

    2014-01-01

    High resolution magic angle spinning 1 H nuclear magnetic resonance spectroscopy (HR-MAS NMR) is a useful technique for evaluation of intact cells and tissues. However, optimal NMR parameters are crucial in obtaining reliable results. To identify the key steps for the optimization of HR-MAS NMR parameters, we assessed different pulse sequences and NMR parameters using sarcoma 180 (S180) cells. A complete assignment of the metabolites of S180 is given to assist future studies. (author)

  2. {sup 1}H HR-MAS NMR and S180 cells: metabolite assignment and evaluation of pulse sequence

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Aline L. de; Martinelli, Bruno César B.; Lião, Luciano M. [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Química. Lab. de RMN; Pereira, Flávia C.; Silveira-Lacerda, Elisangela P. [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Ciências Biológicas. Laboratório Genética Molecular e Citogenética; Alcantara, Glaucia B., E-mail: glaucia.alcantara@ufms.br [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Inst. de Química

    2014-07-01

    High resolution magic angle spinning {sup 1}H nuclear magnetic resonance spectroscopy (HR-MAS NMR) is a useful technique for evaluation of intact cells and tissues. However, optimal NMR parameters are crucial in obtaining reliable results. To identify the key steps for the optimization of HR-MAS NMR parameters, we assessed different pulse sequences and NMR parameters using sarcoma 180 (S180) cells. A complete assignment of the metabolites of S180 is given to assist future studies. (author)

  3. Thermal evolution of mullite from gel precursors studied by mass spectrometry and MAS NMR

    International Nuclear Information System (INIS)

    MacKenzie, K.J.D.; Meinhold, R.H.; Patterson, J.A.; Schneider, H.; Schmucker, M.; Voll, D.

    1999-01-01

    Mullite (Al 6 Si 2 O 13 ) has long been a compound of technical importance, being the principal phase formed when clay minerals are heated. More recently, the development of sol-gel hybrid (organic-inorganic) synthesis methods has opened the way for the production of high-purity mullite of controllable grain size, which has excellent potential in high-technology engineering applications. The finished properties of gel-derived mullite depend on the homogeneity of the gel, which is strongly influenced by the starting materials and reaction conditions. A less-understood aspect of the evolution of crystalline mullite from the gel precursor is the effect of the thermal pre-treatment which can lead to the formation of an Al species with a characteristic MAS NMR resonance at about 30 pp. The role of this species, which is often ascribed to 5-coordinated Al is also not well understood. This paper reports an investigation into the relationship between the thermal pre-treatment regime of mullite precursor gels and the appearance of the 30 ppm Al MAS NMR signal as mullite crystallization proceeds. Copyright (1999) Australasian Ceramic Society

  4. Discriminating heavy aerosol, clouds, and fires during SCAR-B: Application of airborne multispectral MAS data

    Science.gov (United States)

    King, Michael D.; Tsay, Si-Chee; Ackerman, Steven A.; Larsen, North F.

    1998-12-01

    A multispectral scanning spectrometer was used to obtain measurements of the reflection function and brightness temperature of smoke, clouds, and terrestrial surfaces at 50 discrete wavelengths between 0.55 and 14.2 μm. These observations were obtained from the NASA ER-2 aircraft as part of the Smoke, Clouds, and Radiation-Brazil (SCAR-B) campaign, conducted over a 1500×1500 km region of cerrado and rain forest throughout Brazil between August 16 and September 11, 1995. Multispectral images of the reflection function and brightness temperature in 10 distinct bands of the MODIS airborne simulator (MAS) were used to derive a confidence in clear sky (or alternatively the probability of cloud), shadow, fire, and heavy aerosol. In addition to multispectral imagery, monostatic lidar data were obtained along the nadir ground track of the aircraft and used to assess the accuracy of the cloud mask results. This analysis shows that the cloud and aerosol mask being developed for operational use on the moderate-resolution imaging spectroradiometer (MODIS), and tested using MAS data in Brazil, is quite capable of separating cloud, aerosol, shadow, and fires during daytime conditions over land.

  5. Multipass membrane air-stripping (MAS) for removing volatile organic compounds (VOCs) from surfactant micellar solutions.

    Science.gov (United States)

    Cheng, Hefa; Hu, Yuanan; Luo, Jian; Sabatini, David A

    2009-10-30

    Air-stripping is one of the most effective technologies for removing volatile organic compounds (VOCs) from surfactant solutions, although the presence of surfactant poses some unique challenges. This study evaluated the effect of a mixed surfactant system on the apparent Henry's law constant of tetrachloroethylene (PCE) and the efficiency of PCE removal from surfactant solutions using a lab-scale hollow fiber membrane contactor. Results show that the presence of surfactant significantly reduced the apparent Henry's law constant of PCE, and the reduction was proportional to the total surfactant concentration. PCE removal efficiency by membrane air-stripping (MAS) decreased as the surfactant system transitioned from solubilization to supersolubilization. Besides significantly reducing the apparent volatility of VOCs, the presence of surfactant brings additional mass transfer resistance in air-stripping, which makes it difficult to achieve high levels of contaminant removal, even at very high air/liquid (A/L) ratios. In contrast, multipass/multistage MAS operated at low A/L ratios could achieve near 100% contaminant removal because of less mass transfer limitation during each stripping pass/stage. Experimental results, together with model calculations demonstrate multipass (and multistage) air-stripping as a cost-effective alternative for removing VOCs from surfactant micellar solutions compared to the options of using large air strippers or operating at high A/L ratios.

  6. El medievalismo fértil de Paloma Díaz-Mas

    Directory of Open Access Journals (Sweden)

    Rafael M. Mérida Jiménez

    2001-01-01

    Full Text Available The author of this article is concerned with trying to understand why Paloma Díaz-Mas, the writer of such an excellent novel as La tierra fértil (1999, has not received much critical attention. He underlines three main reasons. First, she does not live in Madrid or Barcelona and so she is far away from the main centres of cultural power. Second, she teaches Spanish literature in the Basque Country, a political and linguistic community which significantly differs from that of many other writers. Third, she writes historical novels, which does not appear to be very fashionable in Spain these days. Moreover, Díaz-Mas is a woman writer who does not make use of the most commonly available feminine patterns, and she does not seem to offer a model easy to include in a given feminist methodology either. However, Mérida-Jiménez argues that Paloma provides an intelligent deconstruction of “male authority” through subtle rhetorical means, as well as a representation of the weakness of his “domination” in very innovative ways, such as those derived from the dialectics between history and fiction, centrality and marginality, heterosexuality and homosexuality, individual and society, dream and reason or tradition and modernity.

  7. STRESS RESPONSE TO NICKEL IN ASPLENIUM SCOLOPENDRIUM L. AND DRYOPTERIS FILIX-MAS (L. SCHOTT.

    Directory of Open Access Journals (Sweden)

    Oana Alexandra Drăghiceanu

    2016-12-01

    Full Text Available The aim of this study was to determine the physiological response and the defensive potential in species Asplenium scolopendrium L. and Dryopteris filix-mas (L. Schott under the action of nickel. The following experimental variants were tested: 0, 250, 500, 1000, 1500 mg Ni kg-1soil. One month, and three months respectively, after the initiation of the experiment, the amount of assimilating pigments was determined. One month after the initiation of the experiment, there were no significant differences between the variants with Ni and the control as far as the content of chlorophyll (a and b and carotenoids was concerned. The results obtained three months after the inception of the experiment indicate that, at low concentrations, Ni stimulates the synthesis of chlorophyll. In the same period there occurred antioxidant mechanisms: increase in the amount of carotenoids and increased activity of catalase. In the species Dryopteris filix-mas, the variant with 1.000 mg Ni kg-1soil, the amount of chlorophyll was significantly reduced, and the catalase activity was 3 times higher than that obtained in the control group.

  8. Genotyping by sequencing (GBS, an ultimate marker-assisted selection (MAS tool to accelerate plant breeding

    Directory of Open Access Journals (Sweden)

    Jiangfeng eHe

    2014-09-01

    Full Text Available Marker-assisted selection (MAS refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP, have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broaden NGS usages to large crop genomes such as maize and wheat, genotyping by sequencing (GBS has been developed and applied in sequencing multiplexed samples that combine molecular marker discovery and genotyping. GBS is a novel application of NGS protocols for discovering and genotyping SNPs in crop genomes and populations. The GBS approach includes the digestion of genomic DNA with restriction enzymes followed by the ligation of barcode adapter, PCR amplification and sequencing of the amplified DNA pool on a single lane of flow cells. Bioinformatic pipelines are needed to analyze and interpret GBS datasets. As an ultimate MAS tool and a cost-effective technique, GBS has been successfully used in implementing genome-wide association study (GWAS, genomic diversity study, genetic linkage analysis, molecular marker discovery and genomic selection (GS under a large scale of plant breeding programs.

  9. The effect of FF-MAS on porcine cumulus-oocyte complex maturation, fertilization and pronucleus formation in vitro.

    Science.gov (United States)

    Faerge, Inger; Strejcek, Frantisek; Laurincik, Jozef; Rath, Detlef; Niemann, Heiner; Schellander, Karl; Rosenkranz, Christine; Hyttel, Poul Maddox; Grøndahl, Christian

    2006-08-01

    Follicular fluid meiosis-activating sterol (FF-MAS) has been isolated from the follicular fluid (FF) of several species including man. FF-MAS increases the quality of in vitro oocyte maturation, and thus the developmental potential of oocytes exposed to FF-MAS during in vitro maturation is improved. The aim of the present study was to investigate the effects of FF-MAS on porcine oocyte maturation and pronucleus formation in vitro. Porcine cumulus-oocyte complexes (COCs) were isolated from abattoir ovaries and in vitro matured for 48 h in NCSU 37 medium supplemented with 1 mg/l cysteine, 10 ng/ml epidermal growth factor and 50 microM 2-mercaptoethanol with or without 10% porcine follicular fluid (pFF). For the first 22 h, 1 mM db-cAMP and 10 I.E PMSG/hCG was added. The medium was supplemented with 1 microM, 3 microM, 10 microM, 30 microM or 100 microM FF-MAS dissolved in ethanol. After maturation the COCs were denuded mechanically using a fine glass pipette under constant pH and in vitro fertilized with fresh semen (5 x 10(5) spermatozoa/ml). The presumptive zygotes were evaluated 18 h after fertilization. The addition of pFF increased the monospermic as well as the polyspermic penetration of oocytes. In the absence of pFF, the addition of FF-MAS decreased the polyspermic penetration rate, whereas FF-MAS in combination with pFF decreased monospermic and increased polyspermic penetration. The degeneration rate of ova decreased in the presence of FF-MAS irrespective of the presence or absence of pFF. In the absence of pFF, FF-MAS at 3-10 microM increased the number of zygotes with advanced maternal pronuclear stages. In supraphysiological doses, i.e. 30-100 microM, FF-MAS dose-dependently and reversibly inhibited nuclear maturation in the absence of pFF.

  10. Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.

    Science.gov (United States)

    Wang, Lei; de Kloet, Annette D; Pati, Dipanwita; Hiller, Helmut; Smith, Justin A; Pioquinto, David J; Ludin, Jacob A; Oh, S Paul; Katovich, Michael J; Frazier, Charles J; Raizada, Mohan K; Krause, Eric G

    2016-06-01

    Over-activation of the brain renin-angiotensin system (RAS) has been implicated in the etiology of anxiety disorders. Angiotensin converting enzyme 2 (ACE2) inhibits RAS activity by converting angiotensin-II, the effector peptide of RAS, to angiotensin-(1-7), which activates the Mas receptor (MasR). Whether increasing brain ACE2 activity reduces anxiety by stimulating central MasR is unknown. To test the hypothesis that increasing brain ACE2 activity reduces anxiety-like behavior via central MasR stimulation, we generated male mice overexpressing ACE2 (ACE2 KI mice) and wild type littermate controls (WT). ACE2 KI mice explored the open arms of the elevated plus maze (EPM) significantly more than WT, suggesting increasing ACE2 activity is anxiolytic. Central delivery of diminazene aceturate, an ACE2 activator, to C57BL/6 mice also reduced anxiety-like behavior in the EPM, but centrally administering ACE2 KI mice A-779, a MasR antagonist, abolished their anxiolytic phenotype, suggesting that ACE2 reduces anxiety-like behavior by activating central MasR. To identify the brain circuits mediating these effects, we measured Fos, a marker of neuronal activation, subsequent to EPM exposure and found that ACE2 KI mice had decreased Fos in the bed nucleus of stria terminalis but had increased Fos in the basolateral amygdala (BLA). Within the BLA, we determined that ∼62% of GABAergic neurons contained MasR mRNA and expression of MasR mRNA was upregulated by ACE2 overexpression, suggesting that ACE2 may influence GABA neurotransmission within the BLA via MasR activation. Indeed, ACE2 overexpression was associated with increased frequency of spontaneous inhibitory postsynaptic currents (indicative of presynaptic release of GABA) onto BLA pyramidal neurons and central infusion of A-779 eliminated this effect. Collectively, these results suggest that ACE2 may reduce anxiety-like behavior by activating central MasR that facilitate GABA release onto pyramidal neurons within the

  11. New marine commons along the Chilean coast – the management areas (MAs of Peñuelas and Chigualoco

    Directory of Open Access Journals (Sweden)

    Gloria L. Gallardo Fernández

    2011-09-01

    Full Text Available To halt degradation of benthic resources in Chile, management areas (MAs were set up under the Territorial Use Rights in Fisheries (TURFs framework in the late 1990s. Integrated into the global market, MAs have since expanded along the Chilean coast, involving thousands of small-scale artisanal fishers. This paper analyses how economic criteria relates to social and ecological performance of Chilean MAs, by applying TURFs, commons and co-management theory to two cases: MAs Peñuelas and Chigualoco. To collect and analyse data Participatory Rural Appraisal tools, interviews and official statistics and reports were used. Our results show that MAs’ economic benefits are connected to fluctuations on the global market. Adapting to changing world market prices then becomes paramount. TURFs’ main goal is ecological conservation, but achieving this seems to depend on meeting fishers’ livelihoods; failure to do so likely results in failure to meet conservation objectives. A serious weakness of the Chilean TURFs system is that it does not pay enough attention to fishers’ livelihoods or to the global market context. Furthermore, there is a strong relationship between good economic benefits and social sustainability. But irrespective of economic performance, fisher organizations have been empowered and gained increased resource control with the TURFs system. At policy level, a differentiated and more flexible system could be more suitable for existing heterogeneous MAs and their particular economic, social and ecological challenges. For improved economic sustainability and resource conservation, a system with multiple-species managing MAs could be promoted as well. Finally, to enhance theory of commons, co-management and TURFs, we argue for greater acknowledgement of TURFs’ social benefits in addition to economic assessments. More attention should also be paid to global market conditions of which MAs are dependent and in which they are embedded

  12. Low dose multi-detector CT of the chest (iLEAD Study): Visual ranking of different simulated mAs levels

    International Nuclear Information System (INIS)

    Ley-Zaporozhan, Julia; Ley, Sebastian; Krummenauer, Frank; Ohno, Yoshiharu; Hatabu, Hiroto; Kauczor, Hans-Ulrich

    2010-01-01

    Purpose: Detailed evaluation of the lung parenchyma might be impaired by use of low dose CT as image noise increases and subsequently image quality decreases. The aim of our study was to determine the accuracy of visual perception of differences in image quality and noise at low dose chest CT. Materials and methods: Forty-four patients suffering from emphysema underwent CT (Aquilion-16, 120 kV, 150 mAs, 1 mm-collimation). Original raw data were used for simulation of 10 different mAs settings from 10 mAs to 100 mAs in 10 mAs increments. Three representative hard copy images (carina, 4 cm above, 5 cm below) were printed for evaluation of lung parenchyma (high-resolution kernel, lung window) and mediastinum (soft-kernel, soft tissue window). Ranking of expected low mAs level was performed for lung and soft tissue separately based on visual perception by three-blinded chest radiologist independently. Results were compared to the real simulated mAs. Results: The accuracy for correct ranking of the original 150 mAs scan was 89% for lung and 86% for soft tissue while it was 99% for the simulated 10 mAs for both windows. In comparison to the lowest mAs a significant error increase was found for the lung at 60-100 mAs (with error increase of 30-47%) for reader-I; 60-100 mAs for (33-64%) for reader-II and 70-100 mAs (38-57%) for reader-III. For the soft tissue: 60-150 mAs (with error increase of 28-63%) for reader-I; 50-100 mAs (35-56%) for reader-II and 50-90 mAs (35-40%) for reader-III. Conclusion: Simulated dose levels below 60 mAs (=42 mAs eff ) were clearly differentiated from higher dose levels by all readers. Therefore, imaging doses could be lowered down to 60 mAs without a diagnostically relevant increase in noise impairing image quality.

  13. MAS-based Distributed Coordinated Control and Optimization in Microgrid and Microgrid Clusters: A Comprehensive Overview

    DEFF Research Database (Denmark)

    Han, Yang; Zhang, Ke; Hong, Li

    2018-01-01

    the power and energy, stabilize voltage and frequency, achieve economic and coordinated operation among the MGs and MGCs. However, the complex and diverse combinations of distributed generations in multi-agent system increase the complexity of system control and operation. In order to design the optimized...... the consensus is a vital problem in the complex dynamical systems, the distributed MAS-based consensus protocols are systematically reviewed. On the other hand, the communication delay issue, which is inevitable no matter in the low- or high-bandwidth communication networks, is crucial to maintain stability...... of the MGs and MGCs with fixed and random delays. Various control strategies to compensate the effect of communication delays have been reviewed, such as the neural network-based predictive control, the weighted average predictive control, the gain scheduling scheme and synchronization schemes based...

  14. BaHaMAS A Bash Handler to Monitor and Administrate Simulations

    Science.gov (United States)

    Sciarra, Alessandro

    2018-03-01

    Numerical QCD is often extremely resource demanding and it is not rare to run hundreds of simulations at the same time. Each of these can last for days or even months and it typically requires a job-script file as well as an input file with the physical parameters for the application to be run. Moreover, some monitoring operations (i.e. copying, moving, deleting or modifying files, resume crashed jobs, etc.) are often required to guarantee that the final statistics is correctly accumulated. Proceeding manually in handling simulations is probably the most error-prone way and it is deadly uncomfortable and inefficient! BaHaMAS was developed and successfully used in the last years as a tool to automatically monitor and administrate simulations.

  15. 1H CSA parameters by ultrafast MAS NMR: Measurement and applications to structure refinement.

    Science.gov (United States)

    Miah, Habeeba K; Cresswell, Rosalie; Iuga, Dinu; Titman, Jeremy J

    2017-10-01

    A 1 H anisotropic-isotropic chemical shift correlation experiment which employs symmetry-based recoupling sequences to reintroduce the chemical shift anisotropy in ν 1 and ultrafast MAS to resolve 1 H sites in ν 2 is described. This experiment is used to measure 1 H shift parameters for L-ascorbic acid, a compound with a relatively complex hydrogen-bonding network in the solid. The 1 H CSAs of hydrogen-bonded sites with resolved isotropic shifts can be extracted directly from the recoupled lineshapes. In combination with DFT calculations, hydrogen positions in crystal structures obtained from X-ray and neutron diffraction are refined by comparison with simulations of the full two-dimensional NMR spectrum. The improved resolution afforded by the second dimension allows even unresolved hydrogen-bonded sites 1 H to be assigned and their shift parameters to be obtained. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Adding real data to detect emotions by means of smart resource artifacts in MAS

    Directory of Open Access Journals (Sweden)

    Jaime RINCÓN

    2016-12-01

    Full Text Available This article proposes an application of a social emotional model, which allows to extract, analyse, represent and manage the social emotion of a group of entities. Specifically, the application is based on how music can influence in a positive or negative way over emotional states. The proposed approach employs the JaCalIVE framework, which facilitates the development of this kind of environments. A physical device called smart resource offers to agents processed sensor data as a service. So that, agents obtain real data from a smart resource. MAS uses the smart resource as an artifact by means of a specific communications protocol. The framework includes a design method and a physical simulator. In this way, the social emotional model allows the creation of simulations over JaCalIVE, in which the emotional states are used in the decision-making of the agents.

  17. Sensitivity enhancement using paramagnetic relaxation in MAS solid-state NMR of perdeuterated proteins

    Science.gov (United States)

    Linser, Rasmus; Chevelkov, Veniamin; Diehl, Anne; Reif, Bernd

    2007-12-01

    Previously, Ishii et al., could show that chelated paramagnetic ions can be employed to significantly decrease the recycle delay of a MAS solid-state NMR experiment [N.P. Wickramasinghe, M. Kotecha, A. Samoson, J. Past, Y. Ishii, Sensitivity enhancement in C-13 solid-state NMR of protein microcrystals by use of paramagnetic metal ions for optimizing H-1 T-1 relaxation, J. Magn. Reson. 184 (2007) 350-356]. Application of the method is limited to very robust samples, for which sample stability is not compromised by RF induced heating. In addition, probe integrity might be perturbed in standard MAS PRE experiments due to the use of very short duty cycles. We show that these deleterious effects can be avoided if perdeuterated proteins are employed that have been re-crystallized from D 2O:H 2O = 9:1 containing buffer solutions. The experiments are demonstrated using the SH3 domain of chicken α-spectrin as a model system. The labeling scheme allows to record proton detected 1H, 15N correlation spectra with very high resolution in the absence of heteronuclear dipolar decoupling. Cu-edta as a doping reagent yields a reduction of the recycle delay by up to a factor of 15. In particular, we find that the 1H T1 for the bulk H N magnetization is reduced from 4.4 s to 0.3 s if the Cu-edta concentration is increased from 0 mM to 250 mM. Possible perturbations like chemical shift changes or line broadening due to the paramagnetic chelate complex are minimal. No degradation of our samples was observed in the course of the experiments.

  18. Residue specific hydration of primary cell wall potato pectin identified by solid-state 13C single-pulse MAS and CP/MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Larsen, Flemming Hofmann; Chrestensen, Inge Byg; Damager, Iben

    2011-01-01

    Hydration of rhamnogalacturonan-I (RG-I) derived from potato cell wall was analyzed by 13C single-pulse (SP) magic-angle-spinning (MAS) and 13C cross-polarization (CP) MAS nuclear magnetic resonance (NMR) and supported by 2H SP/MAS NMR experiments. The study shows that the arabinan side chains...... hydrate more readily than the galactan side chains and suggests that the overall hydration properties can be controlled by modifying the ratio of these side chains. Enzymatic modification of native (NA) RG-I provided samples with reduced content of arabinan (sample DA), galactan (sample DG), or both side...... chains (sample DB). Results of these samples suggested that hydration properties were determined by the length and character of the side chains. NA and DA exhibited similar hydration characteristics, whereas DG and DB were difficult to hydrate because of the less hydrophilic properties of the rhamnose...

  19. EFEKTIVITAS TRANSFER DAN ANALISIS EKSPRESI GEN IMUNOGENIK TAHAN KOI HERPES VIRUS (KHV PADA IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Khairul Syahputra

    2014-04-01

    Full Text Available Penelitian transfer gen imunogenik tahan KHV (krt-GP11 pada ikan mas telah dilakukan dengan metode elektroporasi sperma menggunakan konsentrasi DNA yang berbeda. Penelitian ini bertujuan untuk mengetahui konsentrasi DNA optimal yang efektif digunakan dalam transfer gen pada ikan mas. Sperma dielektroporasi menggunakan tipe kejutan square wave dengan voltase 50 V dan jumlah kejutan tiga kali. Konsentrasi DNA yang digunakan adalah 10 μg/mL, 50 μg/mL, dan 100 μg/mL. Deteksi transgen pada sperma, embrio, dan larva dilakukan dengan metode PCR menggunakan primer spesifik untuk gen krt-GP11. Ekspresi transgen pada embrio dan larva dianalisis secara semi-kuantitatif dengan metode reverse transcriptase PCR (RT-PCR. Hasil penelitian menunjukkan bahwa gen krt-GP11 terdeteksi pada sperma, embrio, dan larva. Pemberian konsentrasi DNA 10 μg/mL lebih efektif digunakan dalam transfer gen krt-GP11 pada ikan mas, sedangkan peningkatan konsentrasi DNA yang digunakan tidak memberikan hasil yang berbeda terhadap keberhasilan transfer gen pada ikan mas. Ekspresi gen krt-GP11 yang berhasil diintroduksikan pada ikan mas baru dapat teramati dengan baik pada fase embrio.

  20. The demands and benefits of ergonomics in Sri Lankan apparel industry: A case study at MAS holdings.

    Science.gov (United States)

    Abeysekera, John; Illankoon, Prasanna

    2016-10-17

    Apparel exports bring in sizeable foreign income to Sri Lanka. To protect and promote this industry is a paramount need. This can be carried out by applying Human Factors/Ergonomics (HFE) which has proved to control negative effects at work places. This paper reports a case study which describes the demands and benefits of HFE in MAS Holdings which owns a large share of the apparel industry in Sri Lanka. The study consisted of walk through observation survey, a questionnaire survey and ergonomic work place analysis followed by a training programme to selected employees in three companies. Positive responses to questionnaires revealed good ergonomic practices in the work places surveyed. Ergonomically unfit chairs and potential hazards e.g. exposure to noise and hot environment were detected. It is seen that MAS have introduced strategies originated by Toyota Production System viz. 5S, Kaizen, six sigma etc., which are in fact ergonomic methods. A progressive project MAS boast of viz. 'MAS Operating System' (MOS) empowers training and development to employees. MAS Holdings has adequately realized the benefits of applying HFE as evident by the number of awards received. Relevant companies were advised to take appropriate corrective measures to control the potential hazards.

  1. Quantification of a single score (1+) in the Modified Ashworth Scale (MAS), a clinical assessment of spasticity.

    Science.gov (United States)

    Ewoldt, Jourdan K; Lazzaro, Emily C; Roth, Elliot J; Suresh, Nina L

    2016-08-01

    The Modified Ashworth Scale (MAS) is an assessment that is often used by clinicians to grade spasticity in the affected limbs of stroke survivors. The MAS is a function of the angle at which the clinician perceives a resistance to stretch and/or a `catch' during a passive joint rotation. The qualitative nature of the assessment in combination with the low resolution of the scale could result in varied grouping of spastic patients, even for a single score. The objective of this pilot study was to develop a method for the quantification of the MAS, which could provide greater resolution and could eventually guide better informed therapeutic interventions. The MAS assessment at the elbow joint for four stroke survivors with the same clinical MAS score of 1+ was performed by a clinician and quantified using signals from surface electromyography (EMG) and an electrogoniometer. The subjects were tested on both the affected and contralateral upper limbs. The findings from this study show a varied set of signal outputs across four stroke survivors, all graded at 1+. The quantification provides insight as to the mechanisms underlying the passive resistance.

  2. The effect of FF-MAS on porcine cumulus-oocyte complex maturation, fertilization and pronucleus formation in vitro

    DEFF Research Database (Denmark)

    Færge, Inger; Strejcek, Frantisek; Laurincik, Jozef

    2006-01-01

    Follicular fluid meiosis-activating sterol (FF-MAS) has been isolated from the follicular fluid (FF) of several species including man. FF-MAS increases the quality of in vitro oocyte maturation, and thus the developmental potential of oocytes exposed to FF-MAS during in vitro maturaion is improved....... The aim of the present study was to investigate the effects of FF-MAS on porcien oocyte maturation and pronucleus formation in vitro. Porcine cumulus-oocyte complexes (COCs) were isolated from abattoir ovaries and in vitro matured for 48 h in NCSU 37 medium supplemented with 1 mg/1 cysteine, 10 ng....../ml epidermal growth factor and 50µM 2-mercaptoethanol with or without 10% porcine follicular fluid (pFF). For the first 22 h, 1 mM db-cAMP and 10 I.E PMSG/hCG was added. The medium was supplemented with 1 µM, 3 µM, 10 µM, 30 µM or 100 µM FF-MAS dissolved in ethanol. After maturation the COCs were denuded...

  3. PFG-assisted selection and suppression of 1H NMR signals in the solid state under fast MAS

    Science.gov (United States)

    Fischbach, Ingrid; Thieme, Karena; Hoffmann, Anke; Hehn, Manfred; Schnell, Ingo

    2003-11-01

    Under fast MAS conditions, techniques for 1H signal selection and suppression, which have originally been developed for solution-state NMR, become applicable to solids. In this work, we describe how WATERGATE and DANTE pulse sequences can be used under MAS to selectively excite or suppress peaks in 1H solid-state spectra. As known from the liquid-state analogues, signal selection and/or suppression is supported by pulsed-field gradients which selectively dephase and rephase transverse magnetisation. Under MAS, the required field gradients are provided by a simple pair of coils which have been built into a standard fast-MAS probe. PFG-assisted techniques enable efficient selection or suppression of 1H peaks in a single transient of the pulse sequence without the need for phase cycles. Therefore, these tools can readily be incorporated into solid-state MAS NMR experiments, which is demonstrated here for 1H- 1H double-quantum NMR spectra of supramolecular systems. In the examples presented here, the 1H signals of interest are relatively weak and need to be observed despite the presence of the strong 1H signal of long alkyl sidechains. PFG-assisted suppression of this strong perturbing signal is shown to be particularly useful for obtaining unambiguous results.

  4. X-ray fluorescent analysis on Indo-Pacific glass beads from Sungai Mas archaeological sites, Kedah, Malaysia

    International Nuclear Information System (INIS)

    Zuliskandar Ramli; Nik Hassan Shuhaimi; Nik Abdul Rahman; Abdul Latif Samian

    2011-01-01

    Sungai Mas was an ancient port-kingdom located on West Coast of Peninsula Malaysia in a district of Kota Kuala Muda, Kedah, Malaysia. The port-kingdom evolved as an entrepot since fifth century AD and continuously visited by international trader from India, China, Middle East and Europe until eighteenth century AD. Sungai Mas was also one of the Indo-Pacific beads making centers in Southeast Asia since sixth to thirteenth century AD and also produced pottery and brick. X-ray fluorescent analysis (XRF) on Sungai Mas Indo-Pacific beads is carried out to determine whether the glass beads originated from Arikamedu, India or locally made by community in Sungai Mas. Totally, twenty-two samples of beads and beads materials assayed by XRF were chosen. Contents of nine major elements and nine trace elements, which might be present of flux, stabilizer, colorants or opacifier were examined. The elements Si, Na, K, Ca, Fe, Al, Ti, Mn, Mg, Cu, Pb, Zr, Sr, Ba, La, U, Ni and Cr were detectable in all samples. The concentration of elements found are discussed in terms of flux, silica or lead base glass, color and/or opacity of the glass beads and glass samples. The result showed that Sungai Mas produced their own Indo-Pacific beads from sixth to thirteenth century AD. (author)

  5. Modified Ashworth Scale (MAS) Model based on Clinical Data Measurement towards Quantitative Evaluation of Upper Limb Spasticity

    Science.gov (United States)

    Puzi, A. Ahmad; Sidek, S. N.; Mat Rosly, H.; Daud, N.; Yusof, H. Md

    2017-11-01

    Spasticity is common symptom presented amongst people with sensorimotor disabilities. Imbalanced signals from the central nervous systems (CNS) which are composed of the brain and spinal cord to the muscles ultimately leading to the injury and death of motor neurons. In clinical practice, the therapist assesses muscle spasticity using a standard assessment tool like Modified Ashworth Scale (MAS), Modified Tardiue Scale (MTS) or Fugl-Meyer Assessment (FMA). This is done subjectively based on the experience and perception of the therapist subjected to the patient fatigue level and body posture. However, the inconsistency in the assessment is prevalent and could affect the efficacy of the rehabilitation process. Thus, the aim of this paper is to describe the methodology of data collection and the quantitative model of MAS developed to satisfy its description. Two subjects with MAS of 2 and 3 spasticity levels were involved in the clinical data measurement. Their level of spasticity was verified by expert therapist using current practice. Data collection was established using mechanical system equipped with data acquisition system and LABVIEW software. The procedure engaged repeated series of flexion of the affected arm that was moved against the platform using a lever mechanism and performed by the therapist. The data was then analyzed to investigate the characteristics of spasticity signal in correspondence to the MAS description. Experimental results revealed that the methodology used to quantify spasticity satisfied the MAS tool requirement according to the description. Therefore, the result is crucial and useful towards the development of formal spasticity quantification model.

  6. Chemical profile of beans cultivars (Phaseolus vulgaris) by 1H NMR - high resolution magic angle spinning (HR-MAS);Perfil quimico de cultivares de feijao (Phaseolus vulgaris) pela tecnica de high resolution magic angle spinning (HR-MAS)

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Luciano Morais; Choze, Rafael; Cavalcante, Pedro Paulo Araujo; Santos, Suzana da Costa; Ferri, Pedro Henrique, E-mail: luciano@quimica.ufg.b [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Inst. de Quimica; Ferreira, Antonio Gilberto [Universidade Federal de Sao Carlos (UFScar), SP (Brazil). Dept. de Quimica

    2010-07-01

    The application of one-dimensional proton high-resolution magic angle spinning ({sup 1}H HR-MAS) NMR combined with a typical advantages of solid and liquid-state NMR techniques was used as input variables for the multivariate statistical analysis. In this paper, different cultivars of beans (Phaseolus vulgaris) developed and in development by EMBRAPA - Arroz e Feijao were analyzed by {sup 1}H HR-MAS, which have been demonstrated to be a valuable tool in its differentiation according chemical composition and avoid the manipulation of the samples as used in other techniques. (author)

  7. Effect of intrapartum oropharyngeal (IP-OP) suction on meconium aspiration syndrome (MAS) in developing country: A RCT.

    Science.gov (United States)

    Nangia, Sushma; Pal, Mansi M; Saili, Arvind; Gupta, Usha

    2015-12-01

    Evidence about IP-OP suction and selective tracheal intubation in meconium stained neonates is from developed countries. Little information is available about their role in developing countries with high incidence of meconium staining and MAS. This randomized trial was planned to evaluate the effectiveness of IP-OP suction in meconium stained term neonates on prevention of MAS and reduction of its severity. Out of 540 meconium stained full term, cephalic presentation, singleton neonates without major congenital malformations born from June'08 to January'09, 31 were excluded and 509 randomized. In the intervention group IP-OP suction was done at the time of delivery of head using a 10 Fr suction catheter with a negative pressure of 100 mmHg. No IP-OP suction was performed in control group. All neonates with MSAF were assessed as vigorous or non-vigorous after birth and provided care as per NRP guidelines 2005. Two hundred and fifty three neonates were randomized to IP-OP suction and 256 to no IP-OP suction. Eighty-two neonates (16%) developed MAS, the primary outcome parameter, with 40 infants in the intervention group (15.8%) and 42 (16.4%) in the non-intervention group (RR 0.86, 95% CI 0.60-1.54). Incidence of severe MAS was comparable (3.55% vs. 2.34%) (P value=0.40). Other variables like requirement of oxygen >48 h (9.8% vs. 10.5%) and mortality (2.7% vs. 1.7%) were also comparable. IP-OP suctioning did not reduce the incidence or severity of MAS even in a setting of high incidence of MAS in a developing country. The mortality in two groups was comparable. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  8. Decision-making support system based on MAS for emergency response to nuclear accidents of marine pressurized-water reactor

    International Nuclear Information System (INIS)

    Chen Dengke; Zhang Dafa; Jiang Wei; Chen Yonghong

    2007-01-01

    Emergency decision-making to Marine Pressurized-Water Reactor (MPWR) was severely restricted by the complex environment. To enhance the emergency decision-making ability of MPWR, reducing the effect of emergencies, an emergency Decision-making Support System (DSS) which based on Multi-agent System (MAS) was presented. In the system, the HLA/RTI was used as the support environment, and the structure and the Control Agent (SCA), Analyse Agent (AA), Countermeasure Agent (CA), Evaluation Agent (EVA) and Environment Agent (ENA) were designed. The MAS were with the characteristics of autonomy, reactivity and initiative, which were fully used in the system to make effective decision for emergencies. (authors)

  9. TRANSMISI TRANSGEN GLIKOPROTEIN DAN KETAHANAN IKAN MAS (Cyprinus carpio) TRANSGENIK F1 TERHADAP INFEKSI KOI HERPES VIRUS (KHV)

    OpenAIRE

    Khairul Syahputra; Yogi Himawan; Didik Ariyanto

    2016-01-01

    Ketahanan penyakit merupakan salah satu karakter selain pertumbuhan yang potensial dikembangkan dengan metode transgenesis pada ikan budidaya. Penelitian ini bertujuan untuk mengevaluasi transmisi transgen glikoprotein-GP11 (GP11) dari KHV dan menguji ketahanan ikan mas transgenik F1 terhadap infeksi koi herpes virus (KHV). Empat garis keturunan F1 transgenik (B1, B2, SA1, dan SA2) diproduksi dengan menyilangkan ikan mas jantan F0 yang membawa gen GP11 di sperma dengan betina non-transgenik. ...

  10. Relation Between Acid and Catalytic Properties of Chlorinated Gamma-Alumina. a 31p Mas Nmr and Ftir Investigation

    Directory of Open Access Journals (Sweden)

    Guillaume D.

    1999-07-01

    Full Text Available In this paper, we have studied the effect of chlorine on the surface properties of gamma-alumina, especially on their acid properties. The use of FTIR spectroscopy and 31P MAS NMR of adsorbed trimethylphosphine allows to propose a chlorination mechanism. To correlate the surface properties of these chlorinated gamma-alumina with their catalytic properties, we have used a model reaction, the cracking of n-heptane under reforming conditions. The analysis of the correlation between acid properties determined by 31P MAS NMR and the catalytic results (in terms of activities and selectivities allows to identify which sites are involved in the cracking reaction.

  11. Bulk carbohydrate grain filling of barley ß-glucan mutants studied by 1H HR MAS NMR

    DEFF Research Database (Denmark)

    Seefeldt, Helene Fast; Larsen, Flemming Hofmann; Viereck, Nanna

    2008-01-01

    ) during grain filling. For the first time, 1H HR MAS NMR spectra of flour from immature barley seeds are analyzed. Spectral assignments are made using two-dimensional (2D) NMR methods. Both α- and β-glucan biosynthesis were characterized by inspection of the spectra as well as by calibration......Temporal and genotypic differences in bulk carbohydrate accumulation in three barley genotypes differing in the content of mixed linkage β-(1→3),(1→4)-D-glucan (β-glucan) and starch were investigated using proton high-resolution, magic angle spinning, nuclear magnetic resonance (1H HR MAS NMR...

  12. ANALISIS ESTIMASI COST-VOLUME-PROFIT (CVP DALAM HUBUNGANNYA DENGAN PERENCANAAN LABA PADA HOTEL TLOGO MAS SARANGAN

    Directory of Open Access Journals (Sweden)

    Satrijo Budi Wibowo

    2012-12-01

    Full Text Available This research aims to analyze the estimated Cost-Volume-Profit (CVP in association with the Profit Planning at Tlogo Mas Hotel Sarangan. Analytical techniques used in this study were: (1 Classify all costs incurred in the variable costs (variable costs and fixed costs (fixed cost. (2 Method of least squares analysis. (3 Analysis of the breakeven point (Break Event Point / BEP. The results showed that Tlogo Mas Hotel Sarangan determine the profits of 10% of total sales. It is seen from the fluctuations experienced profit growth each year from 2009 to 2011.

  13. TRANSMISI GEN krt-GP11 DAN PERFORMA KETAHANAN IKAN MAS (Cyprinus carpio TRANSGENIK F-2 TERHADAP INFEKSI KHV

    Directory of Open Access Journals (Sweden)

    Khairul Syahputra

    2017-01-01

    Full Text Available Pembentukan ikan mas transgenik merupakan salah satu program penelitian di Balai Penelitian Pemuliaan Ikan, Sukamandi dalam rangka menghasilkan varietas unggul ikan mas tahan infeksi KHV (Koi herpesvirus. Pada tahun 2015 telah dilakukan pembentukan ikan mas transgenik tahan KHV generasi F-2. Penelitian ini bertujuan untuk mengevaluasi transmisi gen krt-GP11, ketahanan ikan mas transgenik F-2 terhadap infeksi KHV, keberadaan marka Cyca-DAB1*05 tahan KHV pada populasi ikan mas transgenik F-2. Ikan mas transgenik F-2 dihasilkan dengan memijahkan ikan mas transgenik F-1 jantan dengan betina non-transgenik. Pengujian transmisi transgen dan deteksi marka ketahanan KHV pada transgenik F-2 dilakukan dengan metode PCR menggunakan primer spesifik untuk transgen krt-GP11 dan gen Cyca-DAB1*05. Evaluasi ketahanan ikan mas transgenik F-2 terhadap infeksi KHV dilakukan dengan uji tantang secara kohabitasi. Hasil penelitian menunjukkan bahwa transmisi gen krt-GP11 pada keturunan F-2 memiliki persentase yang relatif rendah yaitu sebesar 0%-2%. Ikan mas transgenik F-2 memiliki ketahanan relatif baik terhadap KHV dengan sintasan uji tantang sebesar 90% dan tidak berbeda nyata dengan ikan mas pembanding atau non-transgenik (P>0,05. Tingginya pesentase keberadaan marka Cyca-DAB1*05 pada populasi transgenik berperan pada ketahanan ikan mas transgenik terhadap infeksi KHV. Creating of transgenic common carp is one of the breeding programs in Research Institute for Fish Breeding for producing a superior strain of common carp resistant to KHV(Koi herpesvirus. Since 2015, the creation of common carp transgenic has been conducted to produce F2 population resistant to KHV. This study was aimed to evaluate the transmission of krt-GP11 gen,the resistantce of F2 transgenic common carp against to KHV infection, and the existence of Cyca-DAB1*05 marker resistant to KHV in F2 transgenic population. F2 transgenic population has been produced by mating F1 transgenic male with non

  14. Autolīzinga kompānijas AS "mogo" reklāmas kampaņu izstrāde, izmantojot Facebook reklāmas rīkus

    OpenAIRE

    Ābeltiņš, Elvis

    2017-01-01

    Diplomdarba tēma ir “Autolīzinga kompānijas AS “mogo” reklāmas kampaņu izstrāde, izmantojot Facebook reklāmas rīkus”. Vadošais sociālais tīkls Facebook nodrošina plašas reklāmas izvietošanas iespējas un tā auditorijas apjoms ir sasniedzis tradicionālajiem medijiem līdzvērtīgu izmēru. Darba analītiskajā daļā tiek kategorizētas digitālā mārketinga metodes, kā arī apkopota sociālo tīklu lietotāju statistika Latvijā un pasaulē. Projekta daļā autors salīdzina un analizē Facebook reklāmas izvietoša...

  15. PENAMBAHAN CACING TANAH Lumbricus rubellus DAN KEONG MAS Pomacea canaliculata PADA PAKAN AYAM PETELUR DALAM PENINGKATAN KANDUNGAN OMEGA 3 PADA TELUR

    OpenAIRE

    Farmansyah, Muarif

    2015-01-01

    ABSTRAK Penelitian tentang Penambahan Cacing Tanah Lumbricus rubellus dan Keong mas Pomacea canaliculata Pada Pakan Ayam Petelur Dalam Peningkatan Kandungan Omega 3 Pada Telur bertujuan untuk mengetahui hubungan penambahan Cacing tanah Lumbricus rubellus dan Keong mas Pomaceacanaliculata L pada ayam petelur dalam meningkatkan kandungan omega 3. Komposisi pakan yang digunakan antara lain P1 = Pakan standar 80% + 15% cacing tanah lumbricus rubellus+ 5%keong mas Pomacea canaliculata L, P2 =...

  16. Proces wykonywania modeli z nowej generacji mas modelowych stosowanych w metodzie wytapianych modeli – analiza symulacyjna

    Directory of Open Access Journals (Sweden)

    A. Karwiński

    2012-12-01

    Full Text Available W artykule przedstawiono prace związane z zastosowaniem symulacji komputerowych do projektowania procesu wykonywania modelistosowanych w metodzie wytapianych modeli w odniesieniu do właściwości reologicznych masy modelowej. Możliwość wykorzystaniasymulacji komputerowej procesu zapełniania matrycy, wstępna ocena parametrów tej operacji technologicznej oraz analiza zmianywłaściwości reologicznych masy modelowej pozwala na szybkie wprowadzanie modyfikacji w konstrukcji formy metalowej orazdostosowanie parametrów wykorzystywanej masy modelowej w procesie produkcji modelu bez konieczności wykonywania prototypu.Takie możliwości umożliwia program do analizy przepływów CFD Flow3D. Zaimplementowane algorytmy pozwalają na analizowanie wprzestrzeni trójwymiarowej przepływu masy modelowej o różnych właściwościach fizykochemicznych(gęstość oraz reologicznych(lepkość.Prezentowane w artykule zagadnienia stanowią fragment wykonywanych prac w trakcie projektu realizowanego przez instytutOdlewnictwa i Lotos Parafiny. Efektem końcowym projektu będzie opracowanie nowej generacji mas modelowych przeznaczonych doprodukcji wysokiej jakości odlewów precyzyjnych przy zastosowaniu metody wytapianych modeli.

  17. CINEMA E LITERATURA: mediações em “Bonitinha, mas ordinária”

    Directory of Open Access Journals (Sweden)

    Elen Duarte MIRANDA e SILVA

    2011-01-01

    Full Text Available A partir de um intenso movimento de metamorfoses técnicas e narrativas, o cinema passou de seu estado inicial de mero copiador da realidade à categoria de arte e vem estabelecendo uma forte e íntima relação de diálogo com a literatura. É a partir dessa relação que o destaque dessa pesquisa consiste em uma análise sobre a literatura dramatúrgica de Nelson Rodrigues e sua respectiva adaptação pelo cinema de Braz Chediak, com ênfase no trabalho em parceria entre escritor e cineasta:Bonitinha, mas ordinária: até que ponto o filme se subordina ao texto? Há inventividade na inscrição cinematográfica de Braz? Qual o teor criativo da narrativa do cineasta? Em que instância o filme foi produzido? Qual a tendência estética adotada pelo diretor? Essas questões são desvendadas através da colaboração teórica de Roland Barthes, Ismail Xavier, Sábato Malgadi e Robert Stam, bem como alguns outros estudiosos que pensam cinema e literatura e entram em cena para adensarem a análise feita sobre o objeto colocado em foco.

  18. Nutritional value of Rosa spp. l. and Cornus mas l. fruits, as affected by storage conditions

    Directory of Open Access Journals (Sweden)

    Craita-Maria Rosu

    2011-12-01

    Full Text Available A comparison between two storage methods (freezing and drying of fruits, in terms of ascorbic acid, carotenes, total sugar and protein content in Rosa spp. L. species and Cornus mas L. was performed. In the dried rose hips, the major losses were registered at the level of ascorbic acid content (32.04–50.25 %, followed by carotenes (30.85–52.08 %, total sugar (21.57–34.6 % and protein content (21.33–46.89 %. The freezing method resulted in a better preservation of ascorbic acid (only 19.80–29.21 % decrease and total sugar content (3.41–12.94 % increase. In the preserved cornelian cherry fruits, no statistically significant differences were registered between fruits categories, except carotene content, which was dramatically decreased in dried fruits (88.23 %. For cornelian cherry fruits, both storage methods induced a decrease of ascorbic acid and protein contents (57.60 and 46.32 % and an increase of total sugar level (37.60 %.

  19. Can Memory Assessment Services (MAS) in England be categorized? A national survey.

    Science.gov (United States)

    Chrysanthaki, T; Fernandes, B; Smith, S; Black, N

    2017-12-01

    The effectiveness and efficiency of memory assessment services (MASs) is unknown. Our aim was to determine if a typology can be constructed, based on shared structural and process characteristics, as a basis for a non-randomized evaluation of their effectiveness and cost-effectiveness. Survey of random sample of 73 MASs in 2015; comparison of characteristics and investigation of inter-correlation. It was not possible to group characteristics to form the basis of a typology of MASs. However, there was considerable variation in staff numbers (20-fold), new patients per whole-time equivalent (WTE) staff (20-fold), skill mix and the nurse:doctor ratio (1-10). The operational performance also varied: first appointments (50-120 minutes); time for first follow-up (2-12 weeks); frequency of follow-up in first year (1-5). These differences were not associated with the number of new patients per WTE staff or the accreditation status of the MAS. Post diagnosis, all MASs provided pharmacological treatment but the availability of non-pharmacological support varied, with half providing none or only one intervention while others providing four or more. In the absence of any clear typology, evaluation of MASs will need to focus on the impact of individual structural and process characteristics on outcomes. © The Author 2017. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  20. Conformational analysis of capsaicin using 13C, 15N MAS NMR, GIAO DFT and GA calculations

    Science.gov (United States)

    Siudem, Paweł; Paradowska, Katarzyna; Bukowicki, Jarosław

    2017-10-01

    Capsaicin produced by plants from genus Capsicum exerts multiple pharmacological effects and has found applications in food and pharmaceutical industry. The alkaloid was studied by a combined approach: solid-state NMR, GA conformational search and GIAO DFT methods. The 13C CPMAS NMR spectra were recorded using variable contact time and dipolar dephasing experiments. The results of cross-polarization (CP) kinetics, such as TCP values and long T1ρH (100-200 ms), indicated that the capsaicin molecule is fairly mobile, especially at the end of the aliphatic chain. The15N MAS NMR spectrum showed one narrow signal at -255 ppm. Genetic algorithm (GA) search with multi modal optimization was used to find low-energy conformations of capsaicin. Theoretical GIAO DFT calculations were performed using different basis sets to characterize five selected conformations. 13C CPMAS NMR was used as a validation method and the experimental chemical shifts were compared with those calculated for selected stable conformers. Conformational analysis suggests that the side chain can be bent or extended. A comparison of the experimental and the calculated chemical shifts indicates that solid capsaicin does not have the same structure as those established by PWXRD.

  1. Tendencias clave para el tercer gobierno del MAS, Bolivia 2015-2019

    Directory of Open Access Journals (Sweden)

    Xavier Albó

    2016-03-01

    Esta presentación tiene como trasfondo el Plan Nacional de Desarrollo y pretende resaltar algunos de los logros del presidente Evo Morales y los desafíos que enfrenta en su tercer gobierno (2015-2019. Comienza revisando información demográfica básica, según el Censo de 2012, para luego centrarse en la economía: los hidrocarburos, la minería, la producción agropecuaria y la ecología. El boom de la quinua, la expansión de la frontera agrícola y la suspensión de la construcción de una carretera que atraviese el TIPNIS son algunos de los temas que se discuten. Internacionalmente, hay motivos de optimismo con relación a la demanda marítima de Bolivia, mientras que, a nivel nacional, el MAS aseguró una victoria parlamentaria en el año 2014. Las reformas menos exitosas son las del órgano judicial. La presentación termina revisando los movimientos sociales que permitieron la formación la de Asamblea Constituyente y el asunto de la autonomía municipal, departamental e indígena.

  2. Healthcare benefits linked with Below Poverty Line registration in India: Observations from Maharashtra Anaemia Study (MAS).

    Science.gov (United States)

    Ahankari, Anand; Fogarty, Andrew; Tata, Laila; Myles, Puja

    2017-01-01

    A 2015 Lancet paper by Patel et al. on healthcare access in India comprehensively discussed national health programmes where some benefits are linked with the country's Below Poverty Line (BPL) registration scheme. BPL registration aims to support poor families by providing free/subsidised healthcare. Technical issues in obtaining BPL registration by poor families have been previously reported in the Indian literature; however there are no data on family assets of BPL registrants. Here, we provide evidence of family-level assets among BPL registration holders (and non-BPL households) using original research data from the Maharashtra Anaemia Study (MAS). Social and health data from 287 pregnant women and 891 adolescent girls (representing 1178 family households) across 34 villages in Maharashtra state, India, were analysed. Several assets were shown to be similarly distributed between BPL and non-BPL households; a large proportion of families who would probably be eligible were not registered, whereas BPL-registered families often had significant assets that should not make them eligible. This is likely to be the first published evidence where asset distribution such as agricultural land, housing structures and livestock are compared between BPL and non-BPL households in a rural population. These findings may help planning BPL administration to allocate health benefits equitably, which is an integral part of national health programmes.

  3. Characterization of cornelian cherry (Cornus mas L. genotypes - genetic resources for food production in Czech Republic

    Directory of Open Access Journals (Sweden)

    Sochor Jiri

    2014-01-01

    Full Text Available The aim of the study was to determine and compare both technological properties and polyphenol content in fruits of eight cornellian cherry (Cornus mas L. cultivars from Czech Republic. The fruits of cultivar ´Vydubeckij´ had the highest dry matter (17.4% and soluble solid (15.8% content among searched cultivars. The highest crude protein and phosphorus values were determined in the fruits of the ´Titus´ cultivar as 10.9 g of crude protein and 435 mg of phosphorus for per kg fresh weight (FW base. The ´Elegantnyj´ and ´Vydubeckij´ cultivars are found to be more suitable for canning industry. The fruits of the ´Vydubeckij´ cultivar contained 10.8 g of pectin and 22.4 g of citric acid per kg fresh weight base, and could be important for technological use because of their excellent gelling ability. ´Devin´,´Vydubeckij´ and ´Titus´ cultivars had the most valuable source of chlorogenic acid (135.6, 110.9 and 115.1 mg per 100 g FW, respectively and quercetin (24.9, 25.2 and 24.2 mg per 100 g FW, respectively. This work should contribute to the popularization of this fruit specie as a valuable source of technological parameters for human nutrition and the canning industry.

  4. The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats

    Directory of Open Access Journals (Sweden)

    Renata Francik

    2014-01-01

    Full Text Available Cornelian cherry (Cornus mas is a valuable source of phenolic antioxidants. Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology of many diseases including neurological disorders (e.g., Alzheimer’s disease or heart disease. In this study, we examined the effect of an addition of freeze-dried fruit of cornelian cherry on three types of diets: control diet, fructose diet, and diet enriched in fats (high-fat diet. This effect was studied by determining the following antioxidant parameters in both brain tissue and plasma in rats: catalase, ferric reducing ability of plasma, paraoxonase, protein carbonyl groups, and free thiol groups. Results indicate that both fructose diet and high-fat diet affect the antioxidant capacity of the organism. Furthermore, an addition of cornelian cherry resulted in increased activity of catalase in brain tissue, while in plasma it caused the opposite effect. In turn, with regard to paraoxonase activity in both brain tissue and plasma, it had a stimulating effect. Adding cornelian cherry to the tested diets increased the activity of PON in both tested tissues. Moreover, protective effect of fruits of this plant was observed in the process of oxidation of proteins by decreasing levels of protein carbonyl groups and thiol groups in brain tissue as well as in plasma.

  5. PENGEMBANGAN EKOWISATA BERBASIS KERAKYATAN DI BANJAR NYUH KUNING, DESA MAS, UBUD

    Directory of Open Access Journals (Sweden)

    AGUNG SRI SULISTYAWATI

    2015-06-01

    Full Text Available The objective of this study is (1 to identify the potential of Banjar Nyuh Kuning Mas Village, Ubud has to offer as means of attraction in ecotourism which may be accomplished by identifying physical and non physical potential. (2 to develope a community based strategy in ecotourism. The sampling technique used is purposive sampling and accidental sampling. Data collection is accomplished through observatioan, questionaire, focus group discussion and documentation. Data analysis is by qualitative descriptive and SWOT. The result of this study is that Banjar Nyuh Kuning has the potential to be developed as an ecotourism on the basis of physical and non physical grounds. The perception of the community and tourists are in agreement to the developement of ecotourism activity which incorporate local community, nature oriented activity and has the potential to increase their income, thus resulting in a destination for leisure and recreation. There are a few results of alternative strategies such as; development strategies of ecotourism products, development strategies of human resources, development strategies of management and strategies in upgrading security. To make Banjar Nyuh Kuning as an attraction for ecotourism activity which is based on nature then the strategy for development has to be efficient and limited. Further study has to be taken for the marketing aspect and managing ecotourism object to further the developent in a comprehensive manner.

  6. MAS1H NMR Probes Freezing Point Depression of Water and Liquid-Gel Phase Transitions in Liposomes.

    Science.gov (United States)

    Mandal, Abhishek; van der Wel, Patrick C A

    2016-11-01

    The lipid bilayer typical of hydrated biological membranes is characterized by a liquid-crystalline, highly dynamic state. Upon cooling or dehydration, these membranes undergo a cooperative transition to a rigidified, more-ordered, gel phase. This characteristic phase transition is of significant biological and biophysical interest, for instance in studies of freezing-tolerant organisms. Magic-angle-spinning (MAS) solid-state NMR (ssNMR) spectroscopy allows for the detection and characterization of the phase transitions over a wide temperature range. In this study we employ MAS 1 H NMR to probe the phase transitions of both solvent molecules and different hydrated phospholipids, including tetraoleoyl cardiolipin (TOCL) and several phosphatidylcholine lipid species. The employed MAS NMR sample conditions cause a previously noted substantial reduction in the freezing point of the solvent phase. The effect on the solvent is caused by confinement of the aqueous solvent in the small and densely packed MAS NMR samples. In this study we report and examine how the freezing point depression also impacts the lipid phase transition, causing a ssNMR-observed reduction in the lipids' melting temperature (T m ). The molecular underpinnings of this phenomenon are discussed and compared with previous studies of membrane-associated water phases and the impact of membrane-protective cryoprotectants. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  7. Efect of T. harzianumand FitoMas-E® as bioestimulants of the germination y growth of seedlings of tomato

    Directory of Open Access Journals (Sweden)

    Yoerlandy Santana Baños

    2016-07-01

    Full Text Available The research aimed to evaluate the combined effect of T. harzianum and FitoMas-E® on germination and growth of tomato seedlings. In the first test tomato seeds cv. Vyta they were used to treat with solutions FitoMas-E® (2.0 % v / v and T. harzianum strain A-34 concentration of the solid medium of 1.7 x 109 CFU mL-1 . Germination percentage every six hours by placing 50 seeds per Petri dish of 10 cm diameter with five replicates per treatment is evaluated. In a second test the effect of inoculation of T. harzianum and FitoMas-E® on the growth of tomato seedlings in conditions rootball was evaluated, using trays 264 alveoli and substrate made from peat: soil: rice husks (3:2:1. Speed and percentage germination of tomato seeds treated FitoMas-E® and T. harzianum was found, combined use increases the values of stem diameter and total and radical mass, which can be exploited for transplanting plants tomato, generating a possible diminution in production costs.

  8. EVALUASI DAYA TAHAN IKAN MAS HASIL SELEKSI BERDASARKAN MARKA MOLEKULER MHC-II TERHADAP INFEKSI KOI HERPES VIRUS

    Directory of Open Access Journals (Sweden)

    Erma Primanita Hayuningtyas

    2015-03-01

    mengevaluasi daya tahan benih ikan mas F-1 terseleksi terhadap infeksi KHV melalui uji tantang. Sebagai pembanding, digunakan ikan mas populasi benih F-1 non-seleksi dan populasi benih ikan mas dari unit pembenihan rakyat (UPR. Ikan uji berupa benih ikan mas Rajadanu berumur dua bulan dengan bobot ratarata 5,5±0,5 g. Jumlah benih pada masing-masing wadah perlakuan sebanyak 30 ekor dengan tiga kali pengulangan. Wadah pengujian berupa akuarium berukuran 40 cm x 60 cm x 40 cm dengan kepadatan 1 ekor/L. Parameter yang diamati adalah sintasan, deteksi KHV, analisis ekspresi gen MHC-II, dan gambaran darah ikan. Hasil penelitian menunjukkan bahwa populasi benih F-1 terseleksi memiliki daya tahan lebih baik dengan sintasan 93,33% dibandingkan populasi benih F-1 non-seleksi sebesar 85,55% dan populasi benih dari UPR sebesar 81,11%. Daya tahan yang tinggi pada populasi benih F-1 terseleksi didukung oleh hasil deteksi KHV yang negatif dan ersentase jumlah limfosit yang lebih tinggi sebesar 91,67%; serta rendahnya persentase monosit dan heterofil, selain itu, tidak adanya eosinofil dan basofil. Ekspresi gen MHC-II terdeteksi pada berbagai organ, ekspresi tertinggi ditemukan pada organ limpa.

  9. El Branding a les empreses familiars turístiques: El cas del Grup Mas de Torrent

    OpenAIRE

    Presas i Maynegre, Pilar

    2008-01-01

    El projecte estudia la influència de la família en el procés de creació d’una marca cooperativa (branding) d’una empresa familiar turística, així com en l’activitat empresarial que desenvolupa. Aquest es centra en el Grup Mas de Torrent

  10. Improved quantification of alite and belite in anhydrous Portland cements by 29Si MAS NMR: Effects of paramagnetic ions

    DEFF Research Database (Denmark)

    Poulsen, Søren Lundsted; Kocaba, Vanessa; Le Saoût, Gwenn

    2009-01-01

    The applicability, reliability, and repeatability of 29Si MAS NMR for determination of the quantities of alite (Ca3SiO5) and belite (Ca2SiO4) in anhydrous Portland cement was investigated in detail for 11 commercial Portland cements and the results compared with phase quantifications based...

  11. New perspectives of 19F MAS NMR in the characterization of amorphous forms of atorvastatin in dosage formulations

    Czech Academy of Sciences Publication Activity Database

    Brus, Jiří; Urbanová, Martina; Šeděnková, Ivana; Brusová, H.

    2011-01-01

    Roč. 409, 1/2 (2011), s. 62-74 ISSN 0378-5173 R&D Projects: GA MŠk 2B08021 Institutional research plan: CEZ:AV0Z40500505 Keywords : 19F MAS NMR * factor analysis * polymorphism Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.350, year: 2011

  12. KERAGAAN PERTUMBUHAN BENIH IKAN MAS (Cyprinus carpio STRAIN MAJALAYA, LOKAL BOGOR DAN RAJADANU DI KOLAM CIJERUK, BOGOR-JAWA BARAT

    Directory of Open Access Journals (Sweden)

    Otong Zenal Arifin

    2016-11-01

    Full Text Available Penelitian ini bertujuan untuk mendapatkan strain ikan mas yang memiliki keragaan pertumbuhan yang baik sebagai spesies kandidat untuk program seleksi. Tiga strain ikan mas (majalaya, lokal Bogor, dan rajadanu dipelihara dalam jaring yang diletakkan di kolam Instalasi Penelitian Cijeruk, Bogor selama 6 minggu. Hasil penelitian menunjukkan bahwa tidak ada perbedaan nyata untuk parameter pertambahan bobot dan sintasan dari 3 strain ikan mas yang diuji, sedangkan untuk pertambahan panjang individual (mm per bulan ada perbedaan yang sangat nyata (P<0,05. Strain ikan mas rajadanu memiliki pertambahan panjang terbaik (16,0 ± 1,41 dan berbeda dengan majalaya (10,3 ± 4,50 serta lokal (10,8 ± 2,06. Objective of this study is to produce good performance of common carp by comparing three promising strains majalaya, local, and rajadanu. The study was carry out using floating net cages placed in earthen pond at The Cijeruk Germ Plasm Research Station. During the study, growth and survival rate were observed were observed for six weeks. The results indicated there was no significant difference for growth of weight and survival rate. However, growth of standard length was significantly different (P<0.05. Rajadanu made the best growth of standard length (16.0 ± 1.41 and was different from majalaya (10.3 ± 4.50 and local strain (10.8 ± 2.06.

  13. The German Multidimensional Attitude Scale Toward Persons With Disabilities (G-MAS): A Factor Analytical Study Among High-School Students.

    Science.gov (United States)

    Wöhrle, Joachim; Franke, Sebastian; Kissgen, Ruediger

    2017-10-05

    This study investigates the psychometric properties of the Multidimensional Attitudes Scale Toward Persons with Disabilities (MAS) among German 10th graders, to advance knowledge about the situation in German classrooms with regard to attitudes toward persons with disabilities. Four hundred twenty-one German 10th graders attending the most common regular schools of the German educational system completed the MAS. Confirmatory factor analyses, multigroup confirmatory factor analyses, multivariate analyses of variance and model based clustering were used to investigate: the factor structure, invariance of the factor structure across gender and school types, differences on the MAS between gender and school types, and the existence of groups of students with different attitudes. The authors reject previously proposed measurement models of the MAS, based on inadequate model fit. They identify a factor structure of the MAS with good model fit, the German MAS (G-MAS). The G-MAS, like 2 recently reported factor structures, assesses 4 dimensions: behavioral avoidance, positive cognitions, and 2 affective dimensions-calm and negative affect. The G-MAS is invariant across gender, but not across school types. The authors find no differences on these dimensions between students from different types of schools, but there are gender differences. Findings are discussed in light of the outcome that, of the studied sample, less than 1/3 of the students clearly expresses positive attitudes toward persons with disabilities. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. KANDUNGAN KIMIA SERAT KENAF DARI KOMPOS KULIT UDANG DENGAN PESTISIDA ALAMI KEONG MAS

    Directory of Open Access Journals (Sweden)

    Rusmini Rusmini

    2017-10-01

    Full Text Available Kenaf cultivation generally uses chemical fertilizers and pesticides to increase production despite the adverse effects of those chemicals toward environmental ecosystem. Meanwhile, there are a lot of unutilized wastes produced from agriculture and fishery. Kenaf is an environmentally friendly producer of natural fibers and can produce diversified products, such as paper, wallcover, car interior, geotextile, soil safer, fiber drain, particle board, and plastic reinforcement as well as biofuel industry raw materials. The research aims to produce chemistry fiber kenaf best with the provision of organic fertilizer shrimp compost and natural pesticide snail mas. The study used a Randomized Block Design with two factors with the first factor compost of shrimp (k consisting of 3 levels and the second factor was vegetable pesticide consisting of three levels (p. In each of these studies repeated as many as 2 replications so that there are 18 overall treatment. The observed variables of chemical fiber content include holocellulose, cellulose and lignin. Data obtained, analyzed using analysis of variance  and continued with the smallest real difference test at 5% test level. The results showed that there was holocellulose content in the best kenaf fiber in the treatment of p2 k2 that was equal to 80,28005, for the best cellulose content was p0ko taht was equal to 40,5695 %while for lignin was not continued further test because it showed no real difference. Penanaman  tanaman  kenaf  umumnya menggunakan pupuk kimia untuk meningkatkan produksi, padahal pupuk kimia berbahaya bagi ekosistem lingkungan, sementara banyak sekali limbah pertanian dan perikanan yang tidak termanfaatkan bahkan  menjadi sampah.   Kenaf merupakan tanaman penghasil serat alam yang ramah lingkungan dan bisa menghasilkan berbagai produk diversifikasi, seperti : kertas, pelapis dinding, interior mobil, geotekstil, soil safer, fiber drain, particle board, dan reinforcement plastik

  15. Effective combined water and sideband suppression for low-speed tissue and in vivo MAS NMR.

    Science.gov (United States)

    Mobarhan, Yalda Liaghati; Struppe, Jochem; Fortier-McGill, Blythe; Simpson, André J

    2017-08-01

    High-resolution magic angle spinning (HR-MAS) NMR is a powerful technique that can provide metabolic profiles and structural constraints on intact biological and environmental samples such as cells, tissues and living organisms. However, centripetal force from fast spinning can lead to a loss of sample integrity. In analyses focusing on structural organization, metabolite compartmentalization or in vivo studies, it is critical to keep the sample intact. As such, there is growing interest in slow spinning studies that preserve sample longevity. In this study, for example, reducing the spinning rate from 2500 to 500 Hz during the analysis of a living freshwater shrimp increased the 100% survivability threshold from ~14 to 40 h. Unfortunately, reducing spinning rate decreases the intensity of the isotropic signals and increases both the intensity and number of spinning sidebands, which mask spectral information. Interestingly, water suppression approaches such as excitation sculpting and W5 WATERGATE, which are effective at higher spinning rates, fail at lower spinning rates (<2500 Hz) while simpler approaches such as presaturation are not able to effectively suppress water when the ratio of water to biomass is very high, as is the case in vivo. As such there is a considerable gap in NMR approaches which can be used to suppress water signals and sidebands in biological samples at lower spinning rates. This research presents simple but practically important sequences that combine PURGE water suppression with both phase-adjusted spinning sidebands and an analogue of TOSS termed TOSS.243. The result is simple and effective water and sideband suppression even in extremely dilute samples in pure water down to ~100 Hz spinning rate. The approach is introduced, described and applied to a range of samples including, ex vivo worm tissue, Daphnia magna (water fleas), and in vivo Hyalella azteca (shrimp).

  16. Experimental investigation of drying characteristics of cornelian cherry fruits ( Cornus mas L.)

    Science.gov (United States)

    Ozgen, Filiz

    2015-03-01

    Major target of present paper is to investigate the drying kinetics of cornelian cherry fruits ( Cornus mas L.) in a convective dryer, by varying the temperature and the velocity of drying air. Freshly harvested fruits are dried at drying air temperature of 35, 45 and 55 °C. The considered drying air velocities are V air = 1 and 1.5 m/s for each temperature. The required drying time is determined by taking into consideration the moisture ratio measurements. When the moisture ratio reaches up to 10 % at the selected drying air temperature, then the time is determined ( t = 40-67 h). The moisture ratio, fruit temperature and energy requirement are presented as the functions of drying time. The lowest drying time (40 h) is obtained when the air temperature is 55 °C and air velocity is 1.5 m/s. The highest drying time (67 h) is found under the conditions of 35 °C temperature and 1 m/s velocity. Both the drying air temperature and the air velocity significantly affect the required energy for drying system. The minimum amount of required energy is found as 51.12 kWh, at 55 °C and 1 m/s, whilst the maximum energy requirement is 106.7 kWh, at 35 °C and 1.5 m/s. It is also found that, air temperature significantly influences the total drying time. Moreover, the energy consumption is decreasing with increasing air temperature. The effects of three parameters (air temperature, air velocity and drying time) on drying characteristics have also been analysed by means of analysis of variance method to show the effecting levels. The experimental results have a good agreement with the predicted ones.

  17. Reducing radiation dose in liver enhanced CT scan by setting mAs according to plain scan noise

    International Nuclear Information System (INIS)

    Yang Shangwen; He Jian; Yang Xianfeng; Zhou Kefeng; Xin Xiaoyan; Hu Anning; Zhu Bin

    2013-01-01

    Objective: To investigate the feasibility of setting mAs in liver enhanced CT scan according to plain scan noise with fixed mA CT scanner, in order to reduce the radiation dose. Methods: One hundred continuous patients underwent liver enhanced CT scan (group A) prospectively. Two hundred and fifty mAs was used in plain and enhanced CT scans. Noises of plain and venous phase CT images were measured, and the image quality was evaluated. The equation between mAs of enhanced scan and noise of plain scan image was derived. Another 100 continuous patients underwent liver enhanced CT scan (group B). Enhanced scan mAs was calculated from noise on plain scan by using the equation above. Noises on venous phase images were measured and the image quality was measured. Based on body mass index (BMI), patients in groups A and B were divided into three subgroups respectively: BMI < 18.5 kg/m 2 , 18.5 kg/m 2 ≤ BMI < 25.0 kg/m 2 and BMI ≥ 25.0 kg/m 2 . Image quality score was compared with nonparametric rank sum test, CT dose index (CTDI) and effective dose (ED) were measured and compared between each subgroup with 2 independent samples t or t' test. Results: The equation between enhanced scan mAs (mAsX) and plain scan noise (SDp) was as follows: mAsX = mAs1 × [(0.989 × SDp + 1.06) /SDx] 2 , mAs1 = 250 mAs, SDx = 13. In patients with BMI < 18.5 kg/m 2 , ED of group A [(6.86 ± 0.38) mSv, n = 12] was significantly higher than group B [(2.66 ± 0.46) mSv, n = 10)] (t = 18.52, P < 0.01). In patients with 18.5 kg/m 2 ≤ BMI < 25.0 kg/m 2 , ED of group A [(7.08 ± 0.91) mSv, n = 66] was significantly higher than group B [(4.50 ± 1.41) mSv, n = 73] (t' = 10.57, P < 0.01). In patients with BMI ≥ 25.0 kg/m 2 , there was no significant difference between EDs of group A (7.54 ± 0.62 mSv, n = 22) and group B [(8.19 ± 3.16) mSv, n = 17] (t' = 0.89, P = 0.39). Image quality of 5 patients in group A and none in group B did not meet the diagnostic requirement

  18. Who Are the Students Who May Qualify for an Alternate Assessment Based on Modified Academic Achievement Standards (AA-MAS)?: Focus Group Results. Synthesis Report 79

    Science.gov (United States)

    Berndt, Sandra; Ebben, Barbara; Kubinski, Eva; Sim, Grant; Liu, Kristin; Lazarus, Sheryl; Thurlow, Martha; Christian, Elizabeth

    2011-01-01

    Beginning in 2007, federal regulations to two major education laws gave state departments of education the option to develop an alternate assessment based on modified achievement standards (AA-MAS) for some students with disabilities. The regulations stated that the AA-MAS was intended for students who were being instructed in the grade-level…

  19. Polydisperse methyl β-cyclodextrin–epichlorohydrin polymers: variable contact time 13C CP-MAS solid-state NMR characterization

    Directory of Open Access Journals (Sweden)

    Isabelle Mallard

    2015-12-01

    Full Text Available The polymerization of partially methylated β-cyclodextrin (CRYSMEB with epichlorohydrin was carried out in the presence of a known amount of toluene as imprinting agent. Three different preparations (D1, D2 and D3 of imprinted polymers were obtained and characterized by solid-state 13C NMR spectroscopy under cross-polarization magic angle spinning (CP-MAS conditions. The polymers were prepared by using the same synthetic conditions but with different molar ratios of imprinting agent/monomer, leading to morphologically equivalent materials but with different absorption properties. The main purpose of the work was to find a suitable spectroscopic descriptor accounting for the different imprinting process in three homogeneous polymeric networks. The polymers were characterized by studying the kinetics of the cross-polarization process. This approach is based on variable contact time CP-MAS spectra, referred to as VCP-MAS. The analysis of the VCP-MAS spectra provided two relaxation parameters: TCH (the CP time constant and T1ρ (the proton spin-lattice relaxation time in the rotating frame. The results and the analysis presented in the paper pointed out that TCH is sensitive to the imprinting process, showing variations related to the toluene/cyclodextrin molar ratio used for the preparation of the materials. Conversely, the observed values of T1ρ did not show dramatic variations with the imprinting protocol, but rather confirmed that the three polymers are morphologically similar. Thus the combined use of TCH and T1ρ can be helpful for the characterization and fine tuning of imprinted polymeric matrices.

  20. Pengaruh Ekstrak Daun Sirsak (Annona Muricata) terhadap Profil Darah dan Kelulushidupan Ikan Mas (Cyprinus Carpio) yang Diinfeksi Bakteri Aeromonas Hydrophila

    OpenAIRE

    Nurjannah, R. Dewi Dharina; Prayitno, Slamet Budi; Sarjito, Sarjito; Lusiastuti, Angela Mariana

    2013-01-01

    Carp is a freshwater species that is easily cultivated. One of the constraints in cultivating carps (C. carpio) is diseases that ultimately caused mass mortality. The disease that generally affects carp is Motile Aeromonas Septicemia (MAS) caused by Aeromonas hydrophila. Soursop leaves is one of the herbs that can be used as an ingredient to control fish diseases because it contains chemicals that acts bacteriocide. The purpose of this research was to determine the influence and the best dose...

  1. Spectral editing through laser-flash excitation in two-dimensional photo-CIDNP MAS NMR experiments

    Science.gov (United States)

    Sai Sankar Gupta, Karthick Babu; Daviso, Eugenio; Jeschke, Gunnar; Alia, A.; Ernst, Matthias; Matysik, Jörg

    2014-09-01

    In solid-state photochemically induced dynamic nuclear polarization (photo-CIDNP) MAS NMR experiments, strong signal enhancement is observed from molecules forming a spin-correlated radical pair in a rigid matrix. Two-dimensional 13C-13C dipolar-assisted rotational resonance (DARR) photo-CIDNP MAS NMR experiments have been applied to obtain exact chemical shift assignments from those cofactors. Under continuous illumination, the signals are enhanced via three-spin mixing (TSM) and differential decay (DD) and their intensity corresponds to the electron spin density in pz orbitals. In multiple-13C labelled samples, spin diffusion leads to propagation of signal enhancement to all 13C spins. Under steady-state conditions, direct signal assignment is possible due to the uniform signal intensity. The original intensities, however, are inaccessible and the information of the local electron spin density is lost. Upon laser-flash illumination, the signal is enhanced via the classical radical pair mechanism (RPM). The obtained intensities are related to isotropic hyperfine interactions aiso and both enhanced absorptive and emissive lines can be observed due to differences in the sign of the local isotropic hyperfine interaction. Exploiting the mechanism of the polarization, selectivity can be increased by the novel time-resolved two-dimensional dipolar-assisted rotational resonance (DARR) MAS NMR experiment which simplifies the signal assignment compared to complex spectra of the same RCs obtained by continuous illumination. Here we present two-dimensional time-resolved photo-CIDNP MAS NMR experiments providing both directly: signal assignment and spectral editing by sign and strength of aiso. Hence, this experiment provides a direct key to the electronic structure of the correlated radical pair.

  2. Genotyping-by-sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding

    OpenAIRE

    He, Jiangfeng; Zhao, Xiaoqing; Laroche, André; Lu, Zhen-Xiang; Liu, HongKui; Li, Ziqin

    2014-01-01

    Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP), have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS) technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broad...

  3. Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Martina; Brus, Jiří; Šeděnková, Ivana; Policianová, Olivia; Kobera, Libor

    2013-01-01

    Roč. 100, 1 January (2013), s. 59-66 ISSN 1386-1425 R&D Projects: GA ČR GPP106/11/P426; GA MŠk 2B08021 Institutional research plan: CEZ:AV0Z40500505 Institutional support: RVO:61389013 Keywords : solid-state NMR * factor analysis * 19F MAS NMR Subject RIV: FR - Pharmacology ; Medidal Chemistry Impact factor: 2.129, year: 2013

  4. Pengaruh Motivasi, Kepemimpinan, Dan Budaya Organisasi Terhadap Kinerja Karyawan Pada CV.Gajah Mas Millenium Di Bandar Lampung

    OpenAIRE

    Wulan, Sapmaya; DARWIN, Darwin

    2015-01-01

    Kemajuan Perusahaan atau organisasi tentunya didukung oleh kinerja karyawan. Begitu juga yang dialami Perusahaan CV Gajah Mas Millenium yang merupakan Perusahaan yang bergerak di bidang Distributor Vape di Bandar Lampung. Masalah dalam penelitian ini yaitu Pencapaian target tidak selalu mencapai jumlah target yang telah ditentukan, dilihat dari rata-rata 102,3% dan 124,4% target maksimal. Perumusan masalah dalam penelitian ini yaitu apakah motivasi, kepemimpinan dan budaya organisasi ber...

  5. HR-MAS NMR for rapid identification of illicit substances in tablets and Blotter papers seized by Police Department

    International Nuclear Information System (INIS)

    Souza, Luciano F.; Vieira, Tarcísio S.; Lião, Luciano M.; Alcantara, Glaucia B.

    2016-01-01

    Illicit substances found in blotter papers and tablets seized by police are traditionally identified and characterized from extracts of these materials. However, the procedures involved in extraction stages can result in artifacts and even contamination of the samples to be analyzed. On the other hand, high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) is a technique that requires no pretreatment steps, enabling direct analysis of the material, including the analysis of new illegal synthetic psychoactive substances. This study presents and discusses applications of the HR-MAS NMR in the analysis of tablets and blotter papers seized. Additional analysis in solution of the extracts of these materials was performed to compare the obtained spectral resolution signals. The results demonstrated that the HR-MAS NMR allowed the rapid identification of 3,4-methylenedioxy-N-methylcathinone (methylone), 4-methylmethcathinone (mephedrone), 2,5-dimethoxy-4-bromoamphetamine (DOB) and 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2- methoxyphenyl)methyl]ethanamine (25B-NBOMe) in samples of tablets and blotter papers seized in Goiás State, Brazil. (author)

  6. HR-MAS NMR for rapid identification of illicit substances in tablets and Blotter papers seized by Police Department

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Luciano F.; Vieira, Tarcísio S.; Lião, Luciano M., E-mail: lucianoliao@ufg.br [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Química; Alcantara, Glaucia B. [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Instituto de Química

    2016-07-01

    Illicit substances found in blotter papers and tablets seized by police are traditionally identified and characterized from extracts of these materials. However, the procedures involved in extraction stages can result in artifacts and even contamination of the samples to be analyzed. On the other hand, high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) is a technique that requires no pretreatment steps, enabling direct analysis of the material, including the analysis of new illegal synthetic psychoactive substances. This study presents and discusses applications of the HR-MAS NMR in the analysis of tablets and blotter papers seized. Additional analysis in solution of the extracts of these materials was performed to compare the obtained spectral resolution signals. The results demonstrated that the HR-MAS NMR allowed the rapid identification of 3,4-methylenedioxy-N-methylcathinone (methylone), 4-methylmethcathinone (mephedrone), 2,5-dimethoxy-4-bromoamphetamine (DOB) and 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2- methoxyphenyl)methyl]ethanamine (25B-NBOMe) in samples of tablets and blotter papers seized in Goiás State, Brazil. (author)

  7. Heterogeneous Coordination Environments in Lithium-Neutralized Ionomers Identified Using 1H and 7Li MAS NMR

    Science.gov (United States)

    Alam, Todd M.; Jenkins, Janelle E.; Bolintineanu, Dan S.; Stevens, Mark J.; Frischknecht, Amalie L.; Buitrago, C. Francisco; Winey, Karen I.; Opper, Kathleen L.; Wagener, Kenneth B.

    2012-01-01

    The carboxylic acid proton and the lithium coordination environments for precise and random Li-neutralized polyethylene acrylic acid P(E-AA) ionomers were explored using high speed solid-state 1H and 7Li MAS NMR. While the 7Li NMR revealed only a single Li coordination environment, the chemical shift temperature variation was dependent on the precise or random nature of the P(E-AA) ionomer. The 1H MAS NMR revealed two different carboxylic acid proton environments in these materials. By utilizing 1H-7Li rotational echo double resonance (REDOR) MAS NMR experiments, it was demonstrated that the proton environments correspond to different average 1H-7Li distances, with the majority of the protonated carboxylic acids having a close through space contact with the Li. Molecular dynamics simulations suggest that the shortest 1H-7Li distance corresponds to un-neutralized carboxylic acids directly involved in the coordination environment of Li clusters. These solid-state NMR results show that heterogeneous structural motifs need to be included when developing descriptions of these ionomer materials.

  8. Quality of Kelantan drinking water and knowledge, attitude and practice among the population of Pasir Mas, Malaysia.

    Science.gov (United States)

    Ab Razak, N H; Praveena, S M; Aris, A Z; Hashim, Z

    2016-02-01

    Information about the quality of drinking water, together with analysis of knowledge, attitude and practice (KAP) analysis and health risk assessment (HRA) remain limited. The aims of this study were: (1) to ascertain the level of KAP regarding heavy metal contamination of drinking water in Pasir Mas; (2) to determine the concentration of heavy metals (Al, Cr, Cu, Fe, Ni, Pb, Zn and Cd) in drinking water in Pasir Mas; and (3) to estimate the health risks (non-carcinogenic and carcinogenic) caused by heavy metal exposure through drinking water using hazard quotient and lifetime cancer risk. Information on KAP was collected using a standardized questionnaire. Heavy metal analysis of drinking water samples was performed using graphite furnace atomic absorption spectrophotometry. The population of Pasir Mas has good knowledge (80%), a less positive attitude (93%) and good practice (81%) towards heavy metal contamination of drinking water. The concentrations of heavy metals analysed in this study were found to be below the permissible limits for drinking water set by the Malaysian Ministry of Health and the World Health Organization. The HRA showed no potential non-carcinogenic and carcinogenic risks from the intake of heavy metal through drinking water. By investigating the quality of drinking water, KAP and HRA, the results of this study will provide authorities with the knowledge and resources to improve the management of drinking water quality in the future. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  9. A new aluminium-hydrate species in hydrated Portland cements characterized by 27Al and 29Si MAS NMR spectroscopy

    International Nuclear Information System (INIS)

    Andersen, Morten Daugaard; Jakobsen, Hans J.; Skibsted, Jorgen

    2006-01-01

    Recent 27 Al MAS NMR studies of hydrated Portland cements and calcium-silicate-hydrate (C-S-H) phases have shown a resonance from Al in octahedral coordination, which cannot be assigned to the well-known aluminate species in hydrated Portland cements. This resonance, which exhibits the isotropic chemical shift δ iso = 5.0 ppm and the quadrupole product parameter P Q = 1.2 MHz, has been characterized in detail by 27 Al MAS and 27 Al{ 1 H} CP/MAS NMR for different hydrated white Portland cements and C-S-H phases. These experiments demonstrate that the resonance originates from an amorphous or disordered aluminate hydrate which contains Al(OH) 6 3- or O x Al(OH) 6-x (3+x)- units. The formation of the new aluminate hydrate is related to the formation of C-S-H at ambient temperatures, however, it decomposes by thermal treatment at temperatures of 70-90 o C. From the experiments in this work it is proposed that the new aluminate hydrate is either an amorphous/disordered aluminate hydroxide or a calcium aluminate hydrate, produced as a separate phase or as a nanostructured surface precipitate on the C-S-H phase. Finally, the possibilities of Al 3+ for Ca 2+ substitution in the principal layers and interlayers of the C-S-H structure are discussed

  10. SUBTITUSI TEPUNG IKAN DENGAN TEPUNG KEONG MAS (Pomacea sp. DALAM PAKAN PEMBESARAN IKAN KERAPU MACAN (Epinephelus fuscoguttatus

    Directory of Open Access Journals (Sweden)

    Usman Usman

    2016-11-01

    Full Text Available Penelitian ini dilakukan untuk mendapatkan informasi tentang dosis optimum subtitusi tepung ikan dengan tepung keong mas dalam pakan pembesaran ikan kerapu macan. Ikan uji yang digunakan berupa gelondongan ikan kerapu macan berukuran bobot rata-rata 27,1 ± 1,38 g ditebar dalam keramba jaring apung ukuran 1 x 1 x 2 m3 dengan kepadatan 16 ekor/keramba. Perlakuan yang dicobakan adalah dosis tepung keong mas (GSM dalam pakan yaitu: 0% (GSM0, 10% (GSM10, 20% (GSM20, 30% (GSM30, dan 40% (GSM40 dengan menurunkan kadar tepung ikan pakan. Unit penelitian diset dengan rancangan acak lengkap. Selama pemeliharaan, ikan diberi pakan uji secara satiasi selama 140 hari. Hasil penelitian menunjukkan bahwa ikan yang diberi pakan dengan kandungan tepung keong mas 0%—30% memiliki nilai laju pertumbuhan spesifik, pertambahan bobot, efisiensi pakan, efisiensi protein, dan retensi protein yang relatif sama (P>0,05, namun ikan yang diberi pakan dengan kandungan tepung keong mas sebanyak 40% memiliki nilai peubah tersebut yang berbeda nyata (P0,05. Berdasarkan hasil penelitian ini, maka tepung keong mas dapat digunakan hingga 30% dalam formulasi pakan ikan kerapu macan. This research was conducted to examine the effects of partially substitution of fish meal (FM in the diets with golden snail meal (GSM on growth performance of tiger grouper, Epinephelus fuscoguttatus. Fifteen net cages of 1 x 1 x 2 m3, each containing 16 tiger groupers with average initial weight of 27.1 ± 1.38 g, were set up randomly in seawater. Five isoprotein and isocaloric diets were formulated to contain 43.5% FM without GSM as control diet (GSM0; 10% GSM + 34.2% FM (GSM10; 20% GSM + 24.9% FM (GSM20, 30% GSM + 15.6% FM (GSM30; and 40% GSM + 6.3% FM (GSM40. The fish were fed twice daily to satiation for 140 days. The fish fed the diet containing 0%—30% GSM had not significantly different (P>0.05 specific growth rate, weight gain, feed efficiency, protein efficiency, and protein retention

  11. ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats.

    Science.gov (United States)

    Abuohashish, Hatem M; Ahmed, Mohammed M; Sabry, Dina; Khattab, Mahmoud M; Al-Rejaie, Salim S

    2017-08-01

    The local role of the renin angiotensin system (RAS) was documented recently beside its conventional systemic functions. Studies showed that the effector angiotensin II (AngII) alters bone health, while inhibition of the angiotensin converting enzyme (ACE-1) preserved these effects. The newly identified Ang1-7 exerts numerous beneficial effects opposing the AngII. Thus, the current study examines the role of Ang1-7 in mediating the osteo-preservative effects of ACEI (captopril) through the G-protein coupled Mas receptor using an ovariectomized (OVX) rat model of osteoporosis. 8 weeks after the surgical procedures, captopril was administered orally (40mgkg -1 d -1 ), while the specific Mas receptor blocker (A-779) was delivered at infusion rate of 400ngkg -1 min -1 for 6 weeks. Bone metabolic markers were measured in serum and urine. Minerals concentrations were quantified in serum, urine and femoral bones by inductive coupled plasma mass spectroscopy (ICP-MS). Trabecular and cortical morphometry was analyzed in the right distal femurs using micro-CT. Finally, the expressions of RAS peptides, enzymes and receptors along with the receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG) were determined femurs heads. OVX animals markedly showed altered bone metabolism and mineralization along with disturbed bone micro-structure. Captopril significantly restored the metabolic bone bio-markers and corrected Ca 2+ and P values in urine and bones of estrogen deficient rats. Moreover, the trabecular and cortical morphometric features were repaired by captopril in OVX groups. Captopril also improved the expressions of ACE-2, Ang1-7, Mas and OPG, while abolished OVX-induced up-regulation of ACE-1, AngII, Ang type 1 receptor (AT1R) and RANKL. Inhibition of Ang1-7 cascade by A-779 significantly eradicated captopril protective effects on bone metabolism, mineralization and micro-structure. A-779 also restored OVX effects on RANKL expression and ACE-1/AngII/AT1R

  12. Chromosomal abnormality rate in human pre-embryos derived from in vitro fertilization cycles cultured in the presence of Follicular-Fluid Meiosis Activating Sterol (FF-MAS).

    Science.gov (United States)

    Bergh, Christina; Loft, Anne; Lundin, Kersti; Ziebe, Sören; Nilsson, Lars; Wikland, Matts; Gröndahl, Christian; Arce, J-C

    2004-09-01

    The objective of the study was to investigate the effect of Follicular-Fluid Meiosis Activating Sterol (FF-MAS) when added to the culture media on the incidence of chromosomal abnormalities and pre-embryo development in human pre-embryos. 243 women undergoing IVF/ICSI treatment donated 353 oocytes in a multicentre, prospective, randomized, double blind, four-arm, controlled trial performed at Danish and Swedish public and private IVF centers. Metaphase II oocytes were randomly assigned to: FF-MAS 5 microM, FF-MAS 20 microM, ethanol 0.2% (vehicle control) or water for injection (inert control). The exposure regimen of FF-MAS to the human oocytes was 4 h prior to fertilization by ICSI and 20 h exposure post ICSI. The primary endpoint was the incidence of numerical chromosomal abnormalities. Secondary endpoints were cleavage rate and pre-embryo quality. On the pre-embryo level, no significant differences in chromosomal abnormality rate were observed among the four groups. However, the percentage of uniformly normal pre-embryos was significantly lower in the pooled FF-MAS group (5 microM: 12% and 20 microM: 17%) than in the pooled control group (inert control 32% and vehicle control 42%). A high level of mosaicism (41-60%) was found in all groups. At the blastomere level, the percentage of blastomeres categorized as normal was significantly lower in the FF-MAS 5 microM group (41%) and the FF-MAS 20 microM (29%) group versus the inert (52%) and the vehicle (61%) groups. Significantly reduced cleavage and good quality pre-embryo rates were found in both FF-MAS groups. FF-MAS increased the rate of aneuploidy and had detrimental effects on cleavage and pre-embryo development, when exposed both before and after fertilization.

  13. Captopril improves postresuscitation hemodynamics protective against pulmonary embolism by activating the ACE2/Ang-(1-7)/Mas axis.

    Science.gov (United States)

    Xiao, Hong-Li; Li, Chun-Sheng; Zhao, Lian-Xing; Yang, Jun; Tong, Nan; An, Le; Liu, Qi-Tong

    2016-11-01

    Acute pulmonary embolism (APE) has a very high mortality rate, especially at cardiac arrest and even after the return of spontaneous circulation (ROSC). This study investigated the protective effect of the angiotensin-converting enzyme (ACE) inhibitor captopril on postresuscitation hemodynamics, in a porcine model of cardiac arrest established by APE. Twenty-nine Beijing Landrace pigs were infused with an autologous thrombus leading to cardiac arrest and subjected to standard cardiopulmonary resuscitation and thrombolysis. Ten resuscitated pigs were randomly and equally apportioned to receive either captopril (22.22 mg/kg) infusion or the same volume saline, 30 min after ROSC. Hemodynamic changes and ACE-Ang II-angiotensin II type 1 receptor (AT1R) and ACE2/Ang-(1-7)/Mas receptor axis levels were determined. APE was associated with a decline in mean arterial pressure and a dramatic increase in pulmonary artery pressure and mean right ventricular pressure. After ROSC, captopril infusion was associated with significantly lower mean right ventricular pressure and systemic and pulmonary vascular resistance, faster heart rate, and higher Ang-(1-7) levels, ACE2/ACE, and Ang-(1-7)/Ang II, compared with the saline infusion. The ACE2/Ang-(1-7)/Mas pathway correlated negatively with external vascular lung water and pulmonary vascular permeability and positively with the right cardiac index. In conclusion, in a pig model of APE leading to cardiac arrest, captopril infusion was associated with less mean right ventricular pressure overload after resuscitation, compared with saline infusion. The reduction in systemic and pulmonary vascular resistance associated with captopril may be by inhibiting the ACE-Ang II-AT1R axis and activating the ACE2/Ang-(1-7)/Mas axis.

  14. 27Al Magic Angle Spinning–Nuclear Magnetic Resonance (MAS-NMR) Analyses Applied to Historical Mortars

    Czech Academy of Sciences Publication Activity Database

    Hanzlíček, Tomáš; Perná, Ivana; Brus, Jiří

    2013-01-01

    Roč. 7, č. 2 (2013), s. 153-164 ISSN 1558-3058 R&D Projects: GA AV ČR IAA300460702 Institutional research plan: CEZ:AV0Z30460519; CEZ:AV0Z40500505 Keywords : mortars * magic angle spinning –nuclear magnetic resonance (MAS-NMR) in solid state * alumina-silicates Subject RIV: DM - Solid Waste and Recycling Impact factor: 0.714, year: 2013 http://www.tandfonline.com/doi/abs/10.1080/15583058.2011.624253

  15. Supra-molecular structure and chemical reactivity of cellulose I studied using CP/MAS (sup)13 C-NMR

    CSIR Research Space (South Africa)

    Chunilall, Viren

    2013-08-01

    Full Text Available medium, provided the original work is properly cited. Supra-Molecular Structure and Chemical Reactivity of Cellulose I Studied Using CP/MAS 13C-NMR Viren Chunilall, Tamara Bush and Per Tomas Larsson Additional information is available at the end... can be used in the production of many different types and qualities of pulp samples for a broad range of applications. The sulphite process can be categorised according to the pH into four different types of pulping namely Acid bi-sulphite, Bi...

  16. Microscopic structural analysis of fractured silk fibers from Bombyx mori and Samia cynthia ricini using 13C CP/MAS NMR with a 1 mm microcoil MAS NMR probehead

    KAUST Repository

    Yamauchi, Kazuo

    2010-07-01

    Conformational changes have been studied in silk fibers from the domestic silkworm Bombyx mori and a wild silkworm Samia cynthia ricini as a result of fractured by stretching. About 300 samples consisting of only the fractured regions of [1-13C]Ala or [1-13C]Gly labeled silk fibers were collected and observed by 13C CP/MAS NMR spectra. The total amount of these fractured fibers is only about 1 mg and therefore we used a home-built 1 mm microcoil MAS NMR probehead. A very small increase in the fraction of random coil was noted for the alanine regions of both silk fibroins and for the glycine region of B. mori silk fibroin. However, there is no difference in the spectra before and after fractured for the glycine region of S. c. ricini silk fibroin. Thus, the influence of fracture occurs exclusively at the Ala region for S. c. ricini. The relationship between sequence, fracture and structure is discussed. © 2010 Elsevier Inc. All rights reserved.

  17. The Metacognition Assessment Scale (MAS-A): Results of a pilot study applying a German translation to individuals with schizophrenia spectrum disorders.

    Science.gov (United States)

    Bröcker, Anna-Lena; Bayer, Samuel; Stuke, Frauke; Giemsa, Patrick; Heinz, Andreas; Bermpohl, Felix; Lysaker, Paul H; Montag, Christiane

    2017-09-01

    Metacognition, the capacity 'to think about thinking' and thus to reflect and to master interpersonal problems on a mentalistic basis, is often impaired among patients with schizophrenia spectrum disorders and has been suggested as a potential treatment target. However, little is known about the reliability of its measurement and links with related phenomena. The aim of this study was to validate a German translation of the Metacognition Assessment Scale (MAS-A) as a measure to assess metacognition from free narratives of patients' personally relevant episodes and relationships. MAS-A was applied to narratives of 22 individuals with schizophrenia spectrum disorders together with self-ratings and behavioural tests of metacognitive and related functions such as mentalizing and emotional awareness. Multi-level modelling allowed to calculate inter-rater reliability (IRR) and inter-rater agreement (IRA) and to include test results as level-2 predictors of the aggregated scorings on the MAS-A subscales in order to explore convergent validity. After considering neurocognition and symptom scores as further predictors, aggregated scorings were correlated with psychosocial functioning. There were high IRRs and IRAs all over the ratings. None of the related measures accounted for variance in MAS-A scorings, indicating the existence of separable, non-overlapping constructs. Verbal memory and positive symptoms were significant predictors for MAS-A subscales. MAS-A, but no other measure, displayed significant associations with psychosocial functioning. MAS-A is a reliable expert rating to assess metacognition from patients' free narratives. Considering the link to psychosocial functioning, MAS-A appears to be a promising tool for the evaluation of metacognition. MAS-A is a reliable tool to evaluate metacognitive function from narratives about emotionally relevant topics and meaningful relationships. Metacognition appears separate from neighbouring constructs such as mentalizing

  18. Application of 119Sn CPMG MAS NMR for Fast Characterization of Sn Sites in Zeolites with Natural 119Sn Isotope Abundance

    DEFF Research Database (Denmark)

    G. Kolyagin, Yury; V. Yakimo, Alexander; Tolborg, Søren

    2016-01-01

    119Sn CPMG MAS NMR is demonstrated to be a fast and efficient method for characterization of Sn-sites in Sn-containing zeolites. Tuning of the CPMG echo-train sequence decreases the experimental time by a factor of 5–40 in the case of as-synthesized and hydrated Sn-BEA samples and by 3 orders......-BEA zeolites with natural 119Sn isotope abundance using conventional MAS NMR equipment....

  19. Determination of the structural changes by Raman and 13C CP/MAS NMR spectroscopy on native corn starch with plasticizers

    Science.gov (United States)

    Cozar, O.; Filip, C.; Cioica, N.; Coţa, C.; Tripon, C.; Nagy, E. M.

    2013-11-01

    The plasticizing - antiplasticizing effect of water and glycerol contents on native corn starch samples is investigated by FT-Raman and 13C CP/MAS NMR spectroscopy. The presence of both amorphous and crystalline structural phases was evidenced in pure native corn starch and also in the samples containing plasticizers. Among the crystalline starch structures, the A- and V- types were suggested by CP/MAS NMR spectra.

  20. Noise/dose reduction and image improvements in screening virtual colonoscopy with tube currents of 20 mAs with nonlinear Gaussian filter chains

    Science.gov (United States)

    Rust, Georg-Friedemann; Aurich, Volker; Reiser, Maximilian

    2002-04-01

    Purpose: To evaluate a filter method to extract noise from 20mAs Computed Tomography (CT) data for virtual colonoscopy screening. Method: Nonlinear Gaussian filter chains (NLGF) applied to CT datasets were used to extract noise. To test the efficiency of NLGF a simulation of different ellipsoidal shells with different levels of noise were used. Phantom studies were performed using a multidetector CT (tube currents 10 to 140mAs). 15 patients at high risk for colon cancer underwent a virtual colonoscopy examination (140mAs) and conventional colonoscopy. Different noise levels were added to each CT raw dataset (analog to 40 and 20mAs scans). Virtual endoscopic fly-throughs were performed and rated by two radiologists (image quality). Results: NLGF were able to extract image noise while preserving image structures down to signal--to--noise ratio levels of 0.5. The phantom studies (perspex bars, simulated polyps) were reconstructed without relevant changes between 20 and 140mAs. There were no significant differences between the endoscopic fly-throughs of 140 and 20mAs examinations (2 readers). Conclusion: NLGF is a promising preprocessing method for effective noise reduction in CT datasets. Edges are preserved as well as accentuated in high contrast images.

  1. Klientu attiecību pārvaldības sistēmas izveide autoservisam

    OpenAIRE

    Jaunzems, Ģirts

    2012-01-01

    Diplomdarba tēma ir Klientu attiecību pārvaldības sistēmas izveide autoservisam. Tā mērķis ir izstrādāt un ieviest pielāgotu klientu attiecību pārvaldības sistēmu nelielam autoservisam, tādējādi atvieglojot klientu un viņu darbības vēstures uzskaiti. Lai sasniegtu diplomdarba mērķi, darba autors izpētīja teorētiskos informācijas avotus, salīdzināja divas klientu pārvaldības sistēmas, kā arī izstrādāja sistēmu konkrētam uzņēmumam, veicot arī tās izmaksu analīzi. Diplomdarbā ir secināts, ...

  2. Productivity differences and food security: a metafrontier analysis of rain-fed maize farmers in MasAgro in Mexico

    Directory of Open Access Journals (Sweden)

    M. Laura Donnet

    2017-04-01

    Full Text Available Rain-fed maize production in Mexico includes approximately 6 million hectares which variation in productivity represents huge challenges to meeting the sustainable intensification goals of the Sustainable Modernization of Traditional Agriculture (MasAgro program. We use the information available from farmers participating in this program to investigate the differences in productivity and the effects of the promoted practices and technologies in seven defined rain-fed maize regions. We do this by applying metafrontier analysis to measure the technical efficiency and the technology gap. The results show a range of technical efficiency from 70 to 100%, which indicates the gains that can be achieved through improved management of the current inputs and practices of farmers in the program, and a range of the environment–technology gap between 32 and 82%, which indicates the limitations of the production environment which would require innovations in technologies and policies particularly adapted for the dry, the tropical and the more traditional regions. Furthermore, the results show that the use of hybrid seed and selling into maize markets have the largest impact in increasing maize yields in all regions. The difference between the MasAgro farmers and the average farmers in each region suggest that scaling the project will contribute to increasing maize production and Mexico’s food self-sufficiency.

  3. Genotyping-by-sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding.

    Science.gov (United States)

    He, Jiangfeng; Zhao, Xiaoqing; Laroche, André; Lu, Zhen-Xiang; Liu, HongKui; Li, Ziqin

    2014-01-01

    Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP), have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS) technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broaden NGS usages to large crop genomes such as maize and wheat, genotyping-by-sequencing (GBS) has been developed and applied in sequencing multiplexed samples that combine molecular marker discovery and genotyping. GBS is a novel application of NGS protocols for discovering and genotyping SNPs in crop genomes and populations. The GBS approach includes the digestion of genomic DNA with restriction enzymes followed by the ligation of barcode adapter, PCR amplification and sequencing of the amplified DNA pool on a single lane of flow cells. Bioinformatic pipelines are needed to analyze and interpret GBS datasets. As an ultimate MAS tool and a cost-effective technique, GBS has been successfully used in implementing genome-wide association study (GWAS), genomic diversity study, genetic linkage analysis, molecular marker discovery and genomic selection under a large scale of plant breeding programs.

  4. 1H HR-MAS NMR Spectroscopy and the Metabolite Determination of Typical Foods in Mediterranean Diet

    Directory of Open Access Journals (Sweden)

    Carmelo Corsaro

    2015-01-01

    Full Text Available NMR spectroscopy has become an experimental technique widely used in food science. The experimental procedures that allow precise and quantitative analysis on different foods are relatively simple. For a better sensitivity and resolution, NMR spectroscopy is usually applied to liquid sample by means of extraction procedures that can be addressed to the observation of particular compounds. For the study of semisolid systems such as intact tissues, High-Resolution Magic Angle Spinning (HR-MAS has received great attention within the biomedical area and beyond. Metabolic profiling and metabolism changes can be investigated both in animal organs and in foods. In this work we present a proton HR-MAS NMR study on the typical vegetable foods of Mediterranean diet such as the Protected Geographical Indication (PGI cherry tomato of Pachino, the PGI Interdonato lemon of Messina, several Protected Designation of Origin (PDO extra virgin olive oils from Sicily, and the Traditional Italian Food Product (PAT red garlic of Nubia. We were able to identify and quantify the main metabolites within the studied systems that can be used for their characterization and authentication.

  5. HR MAS1H NMR and chemometrics as useful tool to assess the geographical origin of cocoa beans - Comparison with HR1H NMR.

    Science.gov (United States)

    Marseglia, A; Acquotti, D; Consonni, R; Cagliani, L R; Palla, G; Caligiani, A

    2016-07-01

    Chocolate and cocoa-based products are among the goods with higher added value. A current trend of the cocoa market is to offer to the consumers high quality cocoa products, namely mono-origin cocoa. However, a reliable analytical method able to trace the geographical origin of cocoa is lacking. In this work we tested the capability of HR MAS 1 H NMR combined with chemometrics to assess the geographical origins of 60 fermented and dried cocoa beans of 23 different cocoa producing countries from the three major crop-growing areas (Africa, Central/South America, Asia/Oceania). Metabolic profiling was determined by HR MAS 1 H NMR directly on cocoa powder after the method optimization. The same samples were also subjected to extraction and analysis with HR 1 H NMR. HR MAS 1 H NMR, as 1 H NMR analysis, allowed the simultaneous detection of amino acids, polyalcohols, organic acids, sugars, methylxanthines, catechins. Moreover, HR MAS allows the detection of lipids, not present in the aqueous extract utilized for 1 H NMR. The data set obtained is therefore representative of all classes of cocoa compounds. Untargeted HR MAS 1 H NMR and 1 H NMR datasets were utilized as fingerprint of the samples and elaborated with multivariate statistical methods. A targeted quantitative approach of selected metabolites was possible only with HR 1 H NMR data, because HR MAS 1 H NMR does not give reliable quantitative results. All the approaches adopted showed a discrimination of the cocoa origins. HR MAS presents the advantages to obtain a very rapid picture of the samples, comprising both lipophilic and hydrophilic components, avoiding any sample manipulation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Characterization of some coals and coal intercalations by high-resolution /sup 1/H (BR-24/MAS at 270 MHz) and /sup 13/ (CP/MAS) n. m. r. in solids

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberger, H.; Scheler, G.; Kuenstner, E.

    1988-04-01

    High resolution /sup 1/H n.m.r. studies combining the BR-24 multiple-pulse method after BURUM and RHIM with fast magic-angle sample spinning (MAS), and high resolution solid-state /sup 13/C n.m.r. measurements with cross polarization (CP) and MAS have been used for investigating: a number of coals of different ranks; GDR soft brown coals characterized by textural differences; and typical intercalations to be found in such soft brown coals. The resolution level of /sup 1/H n.m.r. spectra achieved so far at a resonance frequency of 270 MHz permits determination of essential functional groups. The coalification series ranging from soft brown coal to anthracite shows an increase of the aromaticity values f/sub a//sup C/ and also an increase of the f..cap alpha../sup H/ values, which is analogous to the increases in reflectance and carbon content. There are marked differences between the functional groups to be found in detrital and xylite-containing soft brown coals. Tertiary (Miocene) brown coals from the 2nd Lower Lusatian seam (GDR) (i.e. unbedded, poorly bedded, bedded, xylite-containing unbedded, and gelified bedded coals) differ significantly due to variations in micropetrographical composition. Varying amounts of cellulose and lignin are contained in the xylites of the 2nd Lower Lusatian seam. /sup 13/C and /sup 1/H n.m.r. measurements are employed to determine the main constituents of substances such as pyropissite, retinite, fusite and 'monkey hairs' (fossilized rubber). 48 refs., 5 figs., 3 tabs

  7. Incorporation of phosphorus guest ions in the calcium silicate phases of Portland cement from 31P MAS NMR spectroscopy.

    Science.gov (United States)

    Poulsen, Søren L; Jakobsen, Hans J; Skibsted, Jørgen

    2010-06-21

    Portland cements may contain small quantities of phosphorus (typically below 0.5 wt % P(2)O(5)), originating from either the raw materials or alternative sources of fuel used to heat the cement kilns. This work reports the first (31)P MAS NMR study of anhydrous and hydrated Portland cements that focuses on the phase and site preferences of the (PO(4))(3-) guest ions in the main clinker phases and hydration products. The observed (31)P chemical shifts (10 to -2 ppm), the (31)P chemical shift anisotropy, and the resemblance of the lineshapes in the (31)P and (29)Si MAS NMR spectra strongly suggest that (PO(4))(3-) units are incorporated in the calcium silicate phases, alite (Ca(3)SiO(5)) and belite (Ca(2)SiO(4)), by substitution for (SiO(4))(4-) tetrahedra. This assignment is further supported by a determination of the spin-lattice relaxation times for (31)P in alite and belite, which exhibit the same ratio as observed for the corresponding (29)Si relaxation times. From simulations of the intensities, observed in inversion-recovery spectra for a white Portland cement, it is deduced that 1.3% and 2.1% of the Si sites in alite and belite, respectively, are replaced by phosphorus. Charge balance may potentially be achieved to some extent by a coupled substitution mechanism where Ca(2+) is replaced by Fe(3+) ions, which may account for the interaction of the (31)P spins with paramagnetic Fe(3+) ions as observed for the ordinary Portland cements. A minor fraction of phosphorus may also be present in the separate phase Ca(3)(PO(4))(2), as indicated by the observation of a narrow resonance at delta((31)P) = 3.0 ppm for two of the studied cements. (31)P{(1)H} CP/MAS NMR spectra following the hydration of a white Portland cement show that the resonances from the hydrous phosphate species fall in the same spectral range as observed for (PO(4))(3-) incorporated in alite. This similarity and the absence of a large (31)P chemical shift ansitropy indicate that the hydrous (PO(4

  8. Spin-echo based diagonal peak suppression in solid-state MAS NMR homonuclear chemical shift correlation spectra

    Science.gov (United States)

    Wang, Kaiyu; Zhang, Zhiyong; Ding, Xiaoyan; Tian, Fang; Huang, Yuqing; Chen, Zhong; Fu, Riqiang

    2018-02-01

    The feasibility of using the spin-echo based diagonal peak suppression method in solid-state MAS NMR homonuclear chemical shift correlation experiments is demonstrated. A complete phase cycling is designed in such a way that in the indirect dimension only the spin diffused signals are evolved, while all signals not involved in polarization transfer are refocused for cancellation. A data processing procedure is further introduced to reconstruct this acquired spectrum into a conventional two-dimensional homonuclear chemical shift correlation spectrum. A uniformly 13C, 15N labeled Fmoc-valine sample and the transmembrane domain of a human protein, LR11 (sorLA), in native Escherichia coli membranes have been used to illustrate the capability of the proposed method in comparison with standard 13C-13C chemical shift correlation experiments.

  9. Indication of Erosion At Tea - Plantation - Gunung Mas - Puncak - West Java Using Environmental Isotop of 137Cs

    International Nuclear Information System (INIS)

    Suhartini, Nita; Aliyanta, Barokah; Lubis, Ali Arman.

    2002-01-01

    Erosion is a natural phenomena as a result of deforestation. Indication of erosion could be investigated by nuclear method that is used a natural radioisotope of 137C s in the soil. The present of 137C s in environment is a result of the nuclear weapon testing in the middle of 1950's. The result of this pre study showed that the total activity of 137C s in the soil of Tea - Plantation - Gunung Mas - Puncak - West Java is between 150 Bq/m 2- 1872 Bq/m 2. The result showed that the activity of 137C s could be detected, and the erosion or deposition could be seen at the points of the investigation

  10. Residual dipolar couplings in sup 3 sup 1 P MAS spectra of PPh sub 3 substituted cobalt complexes

    CERN Document Server

    Szalontai, G

    2002-01-01

    Residual dipolar couplings between sup 3 sup 1 P- sup 5 sup 9 Co spin pairs were studied in sup 3 sup 1 P MAS spectra of mono- and dinuclear cobalt-triphenylphosphine complexes. These spectra can provide important information such as the scalar coupling between the dipolar phosphorus and the quadrupolar cobalt nuclei normally not available from solution phase studies. In case of complementary (NQR or x-ray) data even the relative orientation of the interacting shielding, dipolar, scalar couplings, and electric field gradient tensors or internuclear distances can be determined. Examples are shown both for well resolved and practically unresolved cases, factors which possibly control the spectral resolution are discussed in detail. (author)

  11. Hydration properties and phosphorous speciation in native, gelatinized and enzymatically modified potato starch analyzed by solid-state MAS NMR

    DEFF Research Database (Denmark)

    Larsen, Flemming Hofmann; Kasprzak, Miroslaw Marek; Lærke, Helle Nygaard

    2013-01-01

    Hydration of granular, gelatinized and molecularly modified states of potato starch in terms of molecular mobility were analyzed by 13C and 31P solid-state MAS NMR. Gelatinization (GEL) tremendously reduced the immobile fraction compared to native (NA) starch granules. This effect was enhanced....... Comparative analysis of wheat and waxy maize starches demonstrated that starches were similar upon gelatinization independent of botanical origin and that the torsion angles of the glycosidic linkages were averages of the crystalline A and B type structures. In starch suspension phosphorous in immobile...... regions was only observed in NA starch. Moreover phosphorous was observed in a minor pH-insensitive form and as major phosphate in hydrated GEL and BE starches....

  12. Morphological and Biochemical Characteristics of Fruits of Different Cornelian Cherry (Cornus mas L. Genotypes from Spontaneous Flora

    Directory of Open Access Journals (Sweden)

    Felicia-Constantina CORNESCU

    2017-12-01

    Full Text Available The current study was carried out on six local cornelian cherry (Cornus mas L. genotypes, grown in Turceni town (Gorj county and Baita village (Hunedoara county, in Romania. Several morphological and biochemical characteristics of cultivars were determined. Fruit weight and fruit flesh ratio of the analyzed genotypes ranged from 1.33 to 2.31 g and 61.53 to 78.58% respectively. Soluble solid contents were determined, the lowest noted as 10% and the highest as 25.5%. Results have shown that there was a high diversity in cornelian cherry populations within different ecological areas. Differences were exhibited in terms of fruit size and biochemical characteristics. The results of the study are useful for attempting to select superior genotypes of cornelian cherry for culture.

  13. 27Al MAS NMR spectroscopic identification of reaction intermediates in the carbothermal reduction and nitridation of alumina

    International Nuclear Information System (INIS)

    Jung, Woo-Sik; Chae, Seen-Ae

    2010-01-01

    The reaction intermediates in the carbothermal reduction and nitridation (CRN) reaction of γ-Al 2 O 3 were identified by 27 Al magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. This identification ruled out the possibility of a reaction mechanism involving the gaseous reaction intermediates. In the CRN reaction of γ-Al 2 O 3 , AlO 4 units were converted to AlN stepwise via AlN x O 4-x (x = 1, 2, 3) intermediates, while AlO 6 units were more slowly converted to AlN than AlO 4 units and the NMR peaks of partially nitridated AlO 6 units were not detected. The NMR peak intensities of partially nitridated AlO 4 units became weaker with increasing reaction temperature.

  14. “La simbología masónica en el Cementerio de Colón”

    Directory of Open Access Journals (Sweden)

    Janet Iglesias Cruz

    2010-01-01

    Full Text Available Los monumentos funerarios son parte de la vida de los pueblos. Una puesta en escena, a través de la piedra, de sus sueños, cumplidos o no. Al transitar por el cementerio de Colón de la Ciudad de La Habana, asistimos a la petrificación de parte del “imaginario colectivo” capitalino. En este ensayo centramos nuestra atención en la presencia de la simbología masónica, a partir de algunos monumentos mortuorios presentes en este recinto. Uno de nuestros objetivos fue registrar la presencia de las logias en el Cementerio y constatar las diversas maneras en que su simbología está presente en sus monumentos funerarios.

  15. Diffusion-based path planning in mobile actuator-sensor networks (MAS-net): some preliminary results

    Science.gov (United States)

    Moore, Kevin L.; Chen, YangQuan; Song, Zhen

    2004-04-01

    In this paper we present preliminary results related to path-planning problems when it is known that the quantities of interest in the system are generated via a diffusion process. The use of mobile sensor-actuator networks (MAS-Net) is proposed for such problems. A discussion of such networks is given, followed by a description of the general framework of the problem. Our strategy assumes that a network of mobile sensors can be commanded to collect samples of the distribution of interest. These samples are then used as constraints for a predictive model of the process. The predicted distribution from the model is then used to determine new sampling locations. A 2-D testbed for studying these ideas is described. The testbed includes a network of ten robots operating as a network using Intel Motes. We also present simulation results from our initial partial differential equation model of the diffusion process in the testbed.

  16. Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.

    Science.gov (United States)

    Su, Yixin; Bi, Jianli; Pulgar, Victor M; Chappell, Mark C; Rose, James C

    2017-06-01

    We previously reported a sex-specific effect of antenatal treatment with betamethasone (Beta) on sodium (Na + ) excretion in adult sheep whereby treated males but not females had an attenuated natriuretic response to angiotensin-(1-7) [Ang-(1-7)]. The present study determined the Na + uptake and nitric oxide (NO) response to low-dose Ang-(1-7) (1 pM) in renal proximal tubule cells (RPTC) from adult male and female sheep antenatally exposed to Beta or vehicle. Data were expressed as percentage of basal uptake or area under the curve for Na + or percentage of control for NO. Male Beta RPTC exhibited greater Na + uptake than male vehicle cells (433 ± 28 vs. 330 ± 26%; P 0.05). Ang-(1-7) significantly inhibited Na + uptake in RPTC from vehicle male (214 ± 11%) and from both vehicle (190 ± 14%) and Beta (209 ± 11%) females but failed to attenuate Na + uptake in Beta male cells. Beta exposure also abolished stimulation of NO by Ang-(1-7) in male but not female RPTC. Both the Na + and NO responses to Ang-(1-7) were blocked by Mas receptor antagonist d-Ala 7 -Ang-(1-7). We conclude that the tubular Ang-(1-7)-Mas-NO pathway is attenuated in males and not females by antenatal Beta exposure. Moreover, since primary cultures of RPTC retain both the sex and Beta-induced phenotype of the adult kidney in vivo they appear to be an appropriate cell model to examine the effects of fetal programming on Na + handling by the renal tubules. Copyright © 2017 the American Physiological Society.

  17. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep.

    Science.gov (United States)

    Marshall, Allyson C; Shaltout, Hossam A; Nautiyal, Manisha; Rose, James C; Chappell, Mark C; Diz, Debra I

    2013-06-01

    Glucocorticoids including betamethasone (BM) are routinely administered to women entering into early preterm labor to facilitate fetal lung development and decrease infant mortality; however, fetal steroid exposure may lead to deleterious long term consequences. In a sheep model of fetal programming, BM-exposed (BMX) offspring exhibit elevated mean arterial pressure (MAP) and decreased baroreflex sensitivity (BRS) for control of heart rate by 0.5-years of age associated with changes in the circulating and renal renin-angiotensin systems (RAS). In the brain solitary tract nucleus, angiotensin (Ang) II actions through the AT1 receptor oppose the beneficial actions of Ang-(1-7) at the Mas receptor for BRS regulation. Therefore, we examined Ang peptides, angiotensinogen (Aogen), and receptor expression in this brain region of exposed and control offspring of 0.5- and 1.8-years of age. Mas protein expression was significantly lower (>40%) in the dorsal medulla of BMX animals at both ages; however, AT1 receptor expression was not changed. BMX offspring exhibited a higher ratio of Ang II to Ang-(1-7) (2.30±0.36 versus 0.99±0.28; p<0.01) and Ang II to Ang I at 0.5-years. Although total Aogen was unchanged, Ang I-intact Aogen was lower in 0.5-year BMX animals (0.78±0.06 vs. 1.94±0.41; p<0.05) suggesting a greater degree of enzymatic processing of the precursor protein in exposed animals. We conclude that in utero BM exposure promotes an imbalance in the central RAS pathways of Ang II and Ang-(1-7) that may contribute to the elevated MAP and lower BRS in this model. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S-Adenosylmethionine Methyltransferase Reaction.

    Science.gov (United States)

    Packianathan, Charles; Li, Jiaojiao; Kandavelu, Palani; Sankaran, Banumathi; Rosen, Barry P

    2018-03-01

    The most common biotransformation of trivalent inorganic arsenic (As(III)) is methylation to mono-, di-, and trimethylated species. Methylation is catalyzed by As(III) S -adenosylmethionine (SAM) methyltransferase (termed ArsM in microbes and AS3MT in animals). Methylarsenite (MAs(III)) is both the product of the first methylation step and the substrate of the second methylation step. When the rate of the overall methylation reaction was determined with As(III) as the substrate, the first methylation step was rapid, whereas the second methylation step was slow. In contrast, when MAs(III) was used as the substrate, the rate of methylation was as fast as the first methylation step when As(III) was used as the substrate. These results indicate that there is a slow conformational change between the first and second methylation steps. The structure of CmArsM from the thermophilic alga Cyanidioschyzon merolae sp. 5508 was determined with bound MAs(III) at 2.27 Å resolution. The methyl group is facing the solvent, as would be expected when MAs(III) is bound as the substrate rather than facing the SAM-binding site, as would be expected for MAs(III) as a product. We propose that the rate-limiting step in arsenic methylation is slow reorientation of the methyl group from the SAM-binding site to the solvent, which is linked to the conformation of the side chain of a conserved residue Tyr70.

  19. Short-term hypoxia upregulated Mas receptor expression to repress the AT1 R signaling pathway and attenuate Ang II-induced cardiomyocyte apoptosis.

    Science.gov (United States)

    Chang, Ruey-Lin; Chang, Chih-Fen; Ju, Da-Tong; Ho, Tsung-Jung; Chang, Tung-Ti; Lin, Jing-Wei; Li, Jia-Chun; Cheng, Shiu-Min; Day, Cecilia-Hsuan; Viswanadha, Vijaya Padma; Huang, Chih-Yang

    2018-03-01

    Hypertension-stimulated cardiac hypertrophy and apoptosis play critical roles in the progression of heart failure. Our previous study suggested that hypertensive angiotensin II (Ang II) enhanced insulin-like growth factor receptor II (IGF-IIR) expression and cardiomyocyte apoptosis, which are involved JNK activation, sirtuin1 (SIRT1) degradation, and heat-shock transcription factor 1 (HSF1) acetylation. Moreover, previous studies have implied that short-term hypoxia (STH) might exert cardioprotective effects. However, the effects of STH on Ang II-induced cardiomyocyte apoptosis remain unknown. In this study, we found that STH reduced myocardial apoptosis caused by Ang II via upregulation of the Mas receptor (MasR) to inhibit the AT 1 R signaling pathway. STH activates MasR to counteract the Ang II pro-apoptotic signaling cascade by inhibiting IGF-IIR expression via downregulation of JNK activation and reduction of SIRT1 degradation. Hence, HSF could remain deacetylated, and repress IGF-IIR expression. These effects decrease the activation of downstream pro-apoptotic and hypertrophic cascades and protect cardiomyocytes from Ang II-induced injury. In addition, we also found that silencing MasR expression enhanced Ang II-induced cardiac hypertrophy and the apoptosis signaling pathway. These findings suggest a critical role for MasR in cardiomyocyte survival. Altogether, our findings indicate that STH protects cardiomyocytes from Ang II-stimulated apoptosis. The protective effects of STH are associated with the upregulation of MasR to inhibit AT 1 R signaling. STH could be a potential therapeutic strategy for cardiac diseases in hypertensive patients. © 2017 Wiley Periodicals, Inc.

  20. Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis.

    Science.gov (United States)

    Abuohashish, Hatem M; Ahmed, Mohammed M; Sabry, Dina; Khattab, Mahmoud M; Al-Rejaie, Salim S

    2017-05-23

    The local and systemic renin angiotensin system (RAS) influences the skeletal system micro-structure and metabolism. Studies suggested angiotensin 1-7 (Ang(1-7)) as the beneficial RAS molecule via Mas receptor activation. This study examines the function of Ang(1-7) in bone micro-architecture and metabolism in an ovariectomized (OVX) rodent model of osteoporosis. OVX rats showed structural and bone metabolic degeneration in parallel with suppressed expressions of the angiotensin converting enzyme-2 (ACE-2)/Ang(1-7)/Mas components. The infusion of Ang(1-7) markedly alleviated the altered bone metabolism and significantly enhanced both trabecular (metaphyseal) and cortical (metaphyseal-diaphyseal) morphometry. Urinary and bones minerals were also improved in OVX rats by Ang(1-7). The infusion of the heptapeptide enhanced ACE-2/Mas receptor expressions, while down-regulated AngII, ACE, and AngII type-1 receptor (AT1R) in OVX animals. Moreover, Ang(1-7) markedly improved osteoprotegerin (OPG) and lowered receptor activator NF-κB ligand (RANKL) expressions. The defensive properties of Ang(1-7) on bone metabolism, structure and minerals were considerably eradicated after blockage of Mas receptor with A-779. Ang(1-7)-induced up-regulated ACE-2/Ang(1-7)/Mas cascade and OPG expressions were abolished and the expressions of ACE/AngII/AT1R and RANKL were provoked by A-779. These findings shows for the first time the novel valuable therapeutic role of Ang(1-7) on bone health and metabolism through the ACE-2/Mas cascade.

  1. Electromagnetic Scattering Analysis of Coated Conductors With Edges Using the Method of Auxiliary Sources (MAS) in Conjunction With the Standard Impedance Boundary Condition (SIBC)

    DEFF Research Database (Denmark)

    Anastassiu, H.T.; D.I.Kaklamani, H.T.; Economou, D.P.

    2002-01-01

    A novel combination of the method of auxiliary sources (MAS) and the standard impedance boundary condition (SIBC) is employed in the analysis of transverse magnetic (TM) plane wave scattering from infinite, coated, perfectly conducting cylinders with square cross sections. The scatterer is initia......A novel combination of the method of auxiliary sources (MAS) and the standard impedance boundary condition (SIBC) is employed in the analysis of transverse magnetic (TM) plane wave scattering from infinite, coated, perfectly conducting cylinders with square cross sections. The scatterer...... efficient than the MoM/SIBC method, proving that the proposed novel combination is a powerful and advantageous computational tool....

  2. Hydration kinetics for the alite, belite, and calcium aluminate phase in Portland cements from 27Al and 29Si MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Skibsted, Jørgen; Jensen, Ole Mejlhede; Jakobsen, Hans Jørgen

    1997-01-01

    29Si magic-angle spinning (MAS) NMR spectroscopy is shown to be a valuable tool for obtaining the quantities of alite and belite in hydrated Portland cements. The hydration (1-180 days) of a white Portland cement with 10 wt.% silica fume added is investigated and the degrees of hydration for alite...... belite, and silica fume are determined. It is demonstrated that 27Al MAS NMR spectra of hydrated Portland cements can give quantitative information about the formation of ettringite and the conversion of this phase to monosulphate during hydration....

  3. Efektifitas Nannochloropsis sp. terhadap sistem imun non-spesifik ikan mas Cyprinus carpio yang diinfeksi Virus Herpes

    Directory of Open Access Journals (Sweden)

    Arafik Lamadi

    2017-11-01

    Full Text Available The aim of this research was to determine the effect of Nannochlorpsisis sp. against the common carp (Cyprinus carpio leukocyte profile, infected with Koi Hepesvirus (KHV. The  descriptive observational method wa used in this study. This research was conducted for 4 weeks, using common carp length 12±0,3 cm as many as 7 fish. The tested experiment was P1: without infested by Nannochlorpsisis sp. and KH; P2: Infested by  Nannochlorpsisis sp. and without KHV infected; P3: Infected by Nannochloropsis sp. and KHV; P4;  Not infected by Nannochlorpsisis sp. and  infected by KHV. Evey tratment in three replications. The results showed that the highest total leukocyte was obtained in P3 (37.600 cells/ml, followed by  P4 (29.650 cells / ml, P2 (28,500 cells / ml and P1 (21,150 cells / ml. Leukocyte differentiation test on P1 (neutrophil 6.2%, lymphocyte 68.0%, monocyte 17.0%, P2 (neutrophil 6.6%, lymphocyte 72.3%, monocyte 18.3%, P3 (neutrophil 7.9%, lymphocyte 66.1%, monocytes 24.3%, P4 (neutrophils 11.2%, lymphocytes 57.6%, monocytes 37.6%. The higher survivla rate was recorded in P2 (100%. It is concluded that  Nannochloropsis sp. can enhance the common carp immune sytem. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian Nannochlorpsis sp. terhadap profil leukosit ikan mas (Cyprinus carpio yang terinfeksi Koi Herves Virus (KHV. Penelitian ini menggunakan metode deskriptif observasional dengan membandingkan hasil pada perlakuan 1 P1: (tanpa pemberian Nannochlorpsis sp. dan tidak diinfeksi KHV, 2 P2 (diberikan Nannochlorpsis sp dan tanpa diinfeksi KHV, 3 P3 (diberikan Nannochlorpsisis sp dan diinfeksi KHV, 4 P4 (tanpa pemberian Nannochlorpsis sp. dan diinfeksi KHV, masing-masing perlakukan 3 kali ulangan. Penelitian ini dilakukan selama 4 minggu dengan menggunakan Ikan mas berukuran 12±0,3  cm sebanyak 120 ekor. Hasil perhitungan total leukosit tertinggi diperoleh pada P3 (37.600 sel/ml, selanjutnya berturut-turut  P4 (29.650  sel

  4. Tagging of blast resistance gene(s) to DNA markers and marker-assisted selection (MAS) in rice improvement

    International Nuclear Information System (INIS)

    Zhuang, J.Y.; Lu, J.; Qian, H.R.; Lin, H.X.; Zheng, K.L.

    1998-01-01

    This paper reports progress made on the tagging of blast resistance gene(s) to DNA markers and on the initiation of marker-assisted selection (MAS) for blast resistance in rice improvement. A pair of near isogenic lines, K8OR and K79S, were developed using a Chinese landrace Hong-jiao-zhan as the resistance donor. Ten putatively positive markers were identified by screening 177 mapped DNA markers. Using the F 2 population of 143 plants and the derived F 3 lines, three Restriction Fragment Length Polymorphism (RFLP) markers (RG81, RG869 and RZ397) on chromosome 12 of rice were identified to be closely linked to the blast resistance gene Pi-12(t). The genetic distance between Pi-12(t) and the closest marker RG869 was 5.1 cM. By employing the bulk segregant analysis (BSA) procedure, six of 199 arbitrary primers were found to produce positive Randomly Amplified Polymorphic DNA (RAPD) bands. Tight linkage between Pi-12(t) and three RAPD bands, each from a different primer, was confirmed after amplification of DNA of all F 2 individuals. Two fragments were cloned and sequenced, and two sequence characterised amplified re-ion (SCAR) markers were established. In two other F 3 populations, Xian-feng I/Tetep and Xian-feng, 1/Hong-jiao-zhan, the blast resistance was found to be controlled by interactions of two or more genes. One resistance gene was located in the vicinity of RG81 in both populations. Work to identify other gene(s) is currently under way. Marker assisted selection for blast resistance was initiated. Crosses were made between elite varieties and blast resistance donors to develop populations for DNA marker-assisted selection of blast resistance. In addition, 48 varieties widely used in current rice breeding programs were provided by rice breeders. DNA marker-based polymorphism among, these varieties and resistance donors were analysed to produce a database for future MAS program. (author)

  5. Ceļu satiksmes drošības direkcijas (CSDD) sociālo reklāmas kampaņu klipu semiotiskā analīze (2003. - 2013.)

    OpenAIRE

    Lapinska, Ginta

    2014-01-01

    Bakalaura darba tēma ir „Ceļu satiksmes drošības direkcijas (CSDD) sociālo reklāmas kampaņu klipu semiotiskā analīze (2003. - 2013.)”. CSDD reklāmas gadu gaitā ir pārliecinājušas reklāmas industriju un auditoriju, tāpēc būtiski ir noskaidrot, kādi ir izmantotie semiotiskie elementi un kā to izmantojums gadu gaitā ir mainījies. Darba mērķis ir izpētīt vienojošos semiotiskos elementus CSDD reklāmas kampaņu klipos no 2003.-2013. gadam. Teorētiskajā daļā aplūkotas tēmas: reklāmas, kampaņas ...

  6. Cooperating systems: Layered MAS

    Science.gov (United States)

    Rochowiak, Daniel

    1990-01-01

    Distributed intelligent systems can be distinguished by the models that they use. The model developed focuses on layered multiagent system conceived of as a bureaucracy in which a distributed data base serves as a central means of communication. The various generic bureaus of such a system is described and a basic vocabulary for such systems is presented. In presenting the bureaus and vocabularies, special attention is given to the sorts of reasonings that are appropriate. A bureaucratic model has a hierarchy of master system and work group that organizes E agents and B agents. The master system provides the administrative services and support facilities for the work groups.

  7. Editorial. Un paso mas

    Directory of Open Access Journals (Sweden)

    Jaime Fandiño Franky

    2014-04-01

    Full Text Available La Fundación Premio Nacional de Epilepsia Margaret Merz de Fandiño, en sus tres convocatorias, ha motivado a los grupos empeñados en el estudio del sistema nervioso para pensar en profundizar en los misterios de la ciencia.

  8. El universo mas pequeno

    CERN Document Server

    Rivera, Alicia

    2007-01-01

    The future of the exploration of the microcosmos will be in a ring formed by more than 8'000 magnets. With the new great particle acceleator LHC, nearly finished in Geneva, scientists will see how the universe was created just after the Big Bang. (3 pages with photos)

  9. Jauniešu nodarbinātības problēmas Latvijā

    OpenAIRE

    Paļčevska, Anastasija

    2017-01-01

    Bakalaurā darbā "JAUNIEŠU NODARBINĀTĪBAS PROBLĒMAS LATVIJĀ" autors izskatīs jautājumu par jauniešu nodarbinātību Latvijā. Jauniešu bezdarbs joprojām ir viena no aktuālākajām problēmām jauniešu nodarbinātības sfērā. Pētījuma mērķis ir studentu un jauno speciālistu vietas noteikšana darba tirgū, kā arī faktoru noteikšana, kas jauniešiem traucē iegūt labu darbu. Autors arī aplūkos jauniešu nodarbinātības atbalsta programmas, kuras strādā Latvijas teritorijā, un veiks salīdzinošo analīzi par nod...

  10. The effect of antitumor glycosides on glioma cells and tissues as studied by proton HR-MAS NMR spectroscopy.

    Directory of Open Access Journals (Sweden)

    Isabel García-Álvarez

    Full Text Available The effect of the treatment with glycolipid derivatives on the metabolic profile of intact glioma cells and tumor tissues, investigated using proton high resolution magic angle spinning ((1H HR-MAS nuclear magnetic resonance (NMR spectroscopy, is reported here. Two compounds were used, a glycoside and its thioglycoside analogue, both showing anti-proliferative activity on glioma C6 cell cultures; however, only the thioglycoside exhibited antitumor activity in vivo. At the drug concentrations showing anti-proliferative activity in cell culture (20 and 40 µM, significant increases in choline containing metabolites were observed in the (1H NMR spectra of the same intact cells. In vivo experiments in nude mice bearing tumors derived from implanted C6 glioma cells, showed that reduction of tumor volume was associated with significant changes in the metabolic profile of the same intact tumor tissues; and were similar to those observed in cell culture. Specifically, the activity of the compounds is mainly associated with an increase in choline and phosphocholine, in both the cell cultures and tumoral tissues. Taurine, a metabolite that has been considered a biomarker of apoptosis, correlated with the reduction of tumor volume. Thus, the results indicate that the mode of action of the glycoside involves, at least in part, alteration of phospholipid metabolism, resulting in cell death.

  11. PENGARUH VARIASI KONSENTRASI BUAH MENGKUDU (Morinda citrifolia TERHADAP MORTALITAS HAMA KEONG MAS (Pomacea caniculata L. SEBAGAI SUMBER BELAJAR BIOLOGI

    Directory of Open Access Journals (Sweden)

    Sukmanah Chomsun

    2013-11-01

    Full Text Available This Reseach aims to study the effect of variation and dose morinda fruit that most effective applicable to mortality gold snail disease, to use product of research as design source study of biologi Junior High School class VIII. Researching on education Laboratory Muhammadiyah Metro of University at November 2012. The design of research employs analisis of varians non-parametrik with Kruskal-Wallis test with four treatments an three time replication. First treatments is control (not having dose, second consentration 50gr/L, third consentration 100gr/L, and fouth consentration 150 gr/L. Product of research to indicated morinda fruit effective to mortality gold snail  disease. Indication is transformation of occured such as descend activity of consume food and mobility, operculum to close, having mucus, not respons, and according  part soft of body to transformation of color to be chalky color or bad color, body of snail to exit for the hard outer layer of body skin, and the gold snail floating on a top suface. This condition indicate that a chemical composite saponin in morinda fruit to affect the process of chemical in a organism, central nerve, and respiration of gold snail. Kata Kunci: Buah mengkudu, mortalitas keong mas, sumber belajar biologi.

  12. PENGARUH IKLAN DAN ATRIBUT PRODUK TERHADAP KEPUTUSAN PEMBELIAN SMARTPHONE SAMSUNG SERI GALAXY (SURVEI PADA PELANGGAN ITC ROXY MAS

    Directory of Open Access Journals (Sweden)

    Basrah Saidani

    2013-04-01

    Full Text Available Generally, the purpose of this research are: 1 to get more knowledge about Advertising, product attributes and the decision to purchase smartphone Samsung Galaxy series,. 2 to get more knowledge about the influence of Advertising to purchasing decisions smartphone Samsung Galaxy series, 3 to get more knowledge about the influence of product attributes to purchasing decisions smartphone Samsung Galaxy series, 4 to get more knowledge about influence of Advertising and product attributes simultaneously the decision to purchase smartphone Samsung Galaxy series. The observation unit in this research is 100 respondents visitors ITC Roxy Mas – Jakarta to purchase smartphone Samsung Galaxy series. Technique of determining the sample using a convenience sampling technique. Data collection techniques using the questionnaire Liker scale from 1 to 5. Descriptive analysis results showed: 1 the Advertising from Samsung Galaxy series is good enough as a whole but still lacking in message Acceptance and message retention. 2 Attribute a good product overall dimesi dominated by product futures, 3 the decision to purchase is dominated by post-purchase where consumers get satisfaction after buying the Samsung Galaxy series. Hypothesis testing results showed: 1 Advertising have a significant effect on purchasing decisions, 2 product attributes have a significant effect on purchasing decisions, 3 Advertising and product attributes a significant effect on purchasing decisions.

  13. Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas Fruits: Effects on Human Skin Cells

    Directory of Open Access Journals (Sweden)

    Maria Perde-Schrepler

    2016-01-01

    Full Text Available Gold nanoparticles (GNPs were obtained by green synthesis with an extract from Cornus mas fruits (GNPs-CM, characterized by several methods, and their biologic effects were evaluated on two cell lines: HaCaT, normal keratinocytes, and A431, epidermoid carcinoma. GNPs were spherical with sizes between 2 and 24 nm. Their optical spectra had a dominant plasmonic band centered at 525 nm; zeta potential distribution was narrow, centered at −19.7 mV, and the mean hydrodynamic diameter was 58 nm. GNPs were visualized in both cell types entering the cells by endocytosis. The amount of gold uptaken by the cells was dose and time dependent. The intracellular concentration of Au ions was higher in HaCaT compared to A431 cells. The toxicity of GNPs-CM was dose dependent being significant only when the highest concentrations were employed. A431 cells were less affected compared to HaCaT cells, but the difference was not statistically significant. ROS production was not significant, except in HaCaT cells at the highest concentration. The comet assay revealed no significant supplementary DNA lesions, while the secretion of inflammatory cytokines was modulated by the presence of GNPs only when the cells were additionally irradiated with UVB. These results recommend GNPs-CM for further testing and possible dermatological applications.

  14. Huiles usagées : schémas IFP de raraffinage Ifp Flowsheets for Rerefining Used Oils

    Directory of Open Access Journals (Sweden)

    Audibert F.

    2006-11-01

    Full Text Available Tout bailleur de licence de procédés de reraffinage des huiles doit rester averti des multiples problèmes concernant ce sujet. Le schéma proposé doit assurer la flexibilité requise du fait des qualités variables de charges et de la législation sur l'environnement. Les schémas complets proposés par l'Institut Français du Pétrole (IFP comprennent un premier flash, une purification physique en profondeur et une étape de raffinage adaptée à la demande locale. Des détails sont donnés sur chaque séquence ainsi que les analyses des produits. Any licensor must be aware of the problems involved in the rerefining of used ails. The proposed flowsheet should ensure the desired flexibility with regard ta feedstockquality variations and environmental - regulation requirements. The complete flowsheets proposed by Institut Français du Pétrole (IFP include a first flash, an in-depth physical purification and a refining step adapted to the local demands. Details are given for each séquence along with product analyses.

  15. Role of Meconium in the Reaction of Airways Smooth Musculature in the Newborn with Meconium Aspiration Syndrome (Mas.

    Directory of Open Access Journals (Sweden)

    Hilmi Islami

    2009-11-01

    Full Text Available The role of meconium in the respiratory system was studied in newborns, who died from various causes (250 up to 3000 g of weight. We monitored tracheal rings response to dopamine, serotonin and ethanol in different concentrations (dopamine: 0,05 mg/ml, 0,5 mg/ml, 5 mg/ml; serotonin (5-HT: 10-4, 10-3, 10-2, 10-1 mol/dm3; ethanol: 0,02 ml, 0,5 ml, 1,0 ml; 96%. Tracheal smooth musculature tonus (TSM was examined in 48 tracheal preparations taken after the newborn exitus due to different reasons. Based on functional researche of isolated preparations of tracheas, it may be concluded that: aspiration of me-conium has not changed the response of TSM to dopamine, serotonin and ethanol (p>0,1 in comparison with the control group, which have died due to different lung inflammatory processes (e.g. pneumonia, bronchopneumonia, atelectasis, cerebral hemorrhage. The results suggest that meconium does not potentiate the constricting action of dopamine, serotonin and ethanol in tracheobronchial system. Meconium causes mild relaxation of the TSM through a mechanism that is not intermediated by the products of cyclooxygenases (prostaglandins, prostacyclins from the tracheal epithelium or proteins. Also, as it seems, the direct activity of many tested acids in the smooth musculature has no significant impact on increase of the airways tonus in MAS syndrome.

  16. Role of meconium in the reaction of airways smooth musculature in the newborn with meconium aspiration syndrome (MAS).

    Science.gov (United States)

    Islami, Hilmi; Bexheti, Sadi; Shabani, Ragip; Nuraj, Bajram; Zeqiri, Fehmi; Sukalo, Aziz; Kurtishi, Ilir; Kutllovci, Skender; Qorraj, Hasime; Disha, Mentor

    2009-11-01

    The role of meconium in the respiratory system was studied in newborns, who died from various causes (250 up to 3000 g of weight). We monitored tracheal rings response to dopamine, serotonin and ethanol in different concentrations (dopamine: 0,05 mg/ml, 0,5 mg/ml, 5 mg/ml; serotonin (5-HT): 10-4, 10-3, 10-2, 10-1 mol/dm3; ethanol: 0,02 ml, 0,5 ml, 1,0 ml; 96%). Tracheal smooth musculature tonus (TSM) was examined in 48 tracheal preparations taken after the newborn exitus due to different reasons. Based on functional researche of isolated preparations of tracheas, it may be concluded that: aspiration of meconium has not changed the response of TSM to dopamine, serotonin and ethanol (p>0,1) in comparison with the control group, which have died due to different lung inflammatory processes (e.g. pneumonia, bronchopneumonia, atelectasis, cerebral hemorrhage). The results suggest that meconium does not potentiate the constricting action of dopamine, serotonin and ethanol in tracheobronchial system. Meconium causes mild relaxation of the TSM through a mechanism that is not intermediated by the products of cyclooxygenases (prostaglandins, prostacyclins) from the tracheal epithelium or proteins. Also, as it seems, the direct activity of many tested acids in the smooth musculature has no significant impact on increase of the airways tonus in MAS syndrome.

  17. Climate change adaptation in Tanjung Mas – Semarang: a comparison between male- and female-headed households

    Science.gov (United States)

    Handayani, W.; Ananda, M. R.; Esariti, L.; Anggraeni, M.

    2018-03-01

    Mainly due to its complexity, the effort to mainstream gender in addressing climate change issues has been far from the satisfying result. However, there is an urgent call to accommodate gender lens issues and to become more gender sensitive in an attempt to have an effective intervention in responding climate change impact. To enrich the reports on gender and climate change adaptation in city-based case, this paper aims to elaborate climate change adaptation in Tanjung Mas – Semarang city focusing on the gender perspective analysis in male- and female-headed households. The quantitative descriptive method is applied to carry out the analyses, including adaptive strategy and gender role analyses. The research result indicates there are not any significant differences in the climate change adaptation strategies applied in male- and female-headed households. This shows that women in the female-headed households, with their double burden, performed well in managing their roles. Therefore, in particular perspective, it may not be relevant to state that woman and female-headed households are likely to be more vulnerable compared with their counterparts.

  18. Written Exercises: Ancestral Magic and Emergent Intellectuals in Mia Couto, Lhoussain Azergui and Dorota Masłowska

    Directory of Open Access Journals (Sweden)

    Ewa Łukaszyk

    2016-12-01

    Full Text Available Written Exercises: Ancestral Magic and Emergent Intellectuals in Mia Couto, Lhoussain Azergui and Dorota Masłowska The article consists in a comparative reading of three novels: Um rio chamado tempo by Mia Couto, Le pain des corbeaux by Lhoussain Azergui and Paw królowej by Dorota Masłowska. In spite of the difference of the historical circumstances of Mozambique, Morocco and Poland, these three books meet at an intersecting point: the emergence of an intelligentsia that uses literacy and writing as an instrument to deconstruct the post-colonial concept of nation and to operate a trans-colonial renegotiation of identity. By the notion of trans-colonial, I understand the opposition against new kinds of symbolic violence that emerged after the end of the colonial period; here this new form of oppression is related to the concept of national unity – an artificial construct that leaves no place for a dualism or pluralism of cultural reality (two shores of the Zambezi river, Arab and Berber dualism in Morocco, “small homelands” in Poland. The young heroes of the novels grasp the pen in order to break through the falseness or the taboos created by the fathers, establishing, at the same time, the relation of solidarity with the world of the grandfathers. The act of writing becomes an actualization of the ancestral universe of magic. The settlement of accounts with the parental generation concerns the vision of nation built upon the resistance against the colonizer (it also refers to the Polish cultural formation, based on the tradition of uprisings and resistance against the Russians.   Ćwiczenia pisemne: magia przodków i nowi intelektualiści w powieściach Mii Couto, Lhoussaina Azerguiego i Doroty Masłowskiej Na podstawie powieści Um rio chamado tempo, uma casa chamada terra Mii Couto (2002, Le pain des corbeaux Lhoussaina Azerguiego (2012 oraz Paw królowej Doroty Masłowskiej (2005 dokonano analizy zjawiska wyłonienia się nowej

  19. Structural investigations of borosilicate glasses containing MoO{sub 3} by MAS NMR and Raman spectroscopies

    Energy Technology Data Exchange (ETDEWEB)

    Caurant, D., E-mail: daniel-caurant@enscp.f [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Ecole Nationale Superieure de Chimie de Paris (ENSCP, ParisTech), 11 rue Pierre et Marie Curie, 75231 Paris (France); Majerus, O.; Fadel, E.; Quintas, A. [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Ecole Nationale Superieure de Chimie de Paris (ENSCP, ParisTech), 11 rue Pierre et Marie Curie, 75231 Paris (France); Gervais, C. [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Universite Pierre et Marie Curie, 75252 Paris (France); Charpentier, T. [CEA, IRAMIS, Service Interdisciplinaire sur les Systemes Moleculaires et Materiaux, CEA Saclay, 91191 Gif-sur-Yvette (France); Neuville, D. [Physique des Mineraux et des Magmas, UMR-CNRS 7047, Institut de Physique du Globe, place Jussieu, 75252 Paris (France)

    2010-01-01

    High molybdenum concentration in glass compositions may lead to alkali and alkaline-earth molybdates crystallization during melt cooling that must be controlled particularly during the preparation of highly radioactive nuclear glassy waste forms. To understand the effect of molybdenum addition on the structure of a simplified nuclear glass and to know how composition changes can affect molybdates crystallization tendency, the structure of two glass series belonging to the SiO{sub 2}-B{sub 2}O{sub 3}-Na{sub 2}O-CaO-MoO{sub 3} system was studied by {sup 29}Si, {sup 11}B, {sup 23}Na MAS NMR and Raman spectroscopies by increasing MoO{sub 3} or B{sub 2}O{sub 3} concentrations. Increasing MoO{sub 3} amount induced an increase of the silicate network reticulation but no significant effect was observed on the proportion of BO{sub 4}{sup -} units and on the distribution of Na{sup +} cations in glass structure. By increasing B{sub 2}O{sub 3} concentration, a strong evolution of the distribution of Na{sup +} cations was observed that could explain the evolution of the nature of molybdate crystals (CaMoO{sub 4} or Na{sub 2}MoO{sub 4}) formed during melt cooling.

  20. Quality of spelt pasta enriched with eggs and identification of eggs using 13C MAS NMR spectroscopy

    Directory of Open Access Journals (Sweden)

    Filipović Jelena S.

    2015-01-01

    Full Text Available This paper deals with the characteristics of spelt pasta enriched with eggs. Eggs were added to spelt farina in the quantity of 0, 124 or 248 g/kg (equivalent to 0, 3 or 6 eggs, respectively. Post-hoc Tukey’s HSD test at 95% confidence limit showed significant differences between various samples. Relatively low coefficients of variation have been obtained for each applied assay (1.25-12.42%, which confirmed the high accuracy measurements and statistically significant results. Standard score analysis is applied for accessing the contribution of eggs content to spelt pasta quality. Maximum scores regarding quality (0.89 and chemical characteristics (0.70, have been obtained for 6 eggs spelt pasta formulation. It is also shown that the presence of eggs in pasta can be clearly confirmed by 13C MAS NMR spectroscopy. Simultaneous increase in area of peak positioned at 29.5 and 176 ppm is directly associated with the increase in the content of added eggs in the corresponding samples. Pertinent data point at positive contribution of eggs to the spelt pasta and also that NMR spectrum can be used in the egg quantity control. [Projekat Ministarstva nauke Republike Srbije, br. TRI 46005 i br. TR 31029

  1. Preču uzskaites sistēmas izstrāde Django ietvarā

    OpenAIRE

    Kokorevičs, Miķelis

    2014-01-01

    Django ietvars ir moderns un pilnvērtīgs tīmekļa ietvars, kas ir veidots Python programmēšanas valodā. Šajā darbā, tiek pētīta Django ietvara funkcionalitāte un piemērotība individuālu preču uzskaites sistēmu izstrādē. Galvenie darba uzdevumi ir izpētīt Django ietvara iespējas un apkopot preču uzskaites sistēmas izstrādei nozīmīgākās priekšrocības. Šī darba rezultātā, tika aprakstīta Django ietvara funkcionalitāte, iespējas un uzbūve. Tika veikts salīdzinājums starp populārākajiem Pyth...

  2. Following Solid-Acid-Catalyzed Reactions by MAS NMR Spectroscopy in Liquid Phase -Zeolite-Catalyzed Conversion of Cyclohexanol in Water

    Energy Technology Data Exchange (ETDEWEB)

    Vjunov, Aleksei [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hu, Mary Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Feng, Ju [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Camaioni, Donald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mei, Donghai [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hu, Jian Z. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhao, Chen [TU Munchen, Garching (Germany); Lercher, Johannes A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); TU Munchen, Garching (Germany)

    2014-01-07

    The catalytic conversion of cyclohexanol on zeolite HBEA in hot liquid water leads to dehydration as well as alkylation products. A novel micro autoclave suitable for application in MAS NMR at high temperatures and pressures is developed and successfully applied to obtain new insight into the mechanistic pathway leading to an understanding of the reactions under selected experimental conditions.

  3. Protein resonance assignment at MAS frequencies approaching 100 kHz: a quantitative comparison of J-coupling and dipolar-coupling-based transfer methods

    Energy Technology Data Exchange (ETDEWEB)

    Penzel, Susanne; Smith, Albert A.; Agarwal, Vipin; Hunkeler, Andreas [ETH Zürich, Physical Chemistry (Switzerland); Org, Mai-Liis; Samoson, Ago, E-mail: ago.samoson@ttu.ee [Tallinn University of Technology, NMR Instituut, Tartu Teadus, Tehnomeedikum (Estonia); Böckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Université de Lyon 1, Institut de Biologie et Chimie des Protéines (France); Ernst, Matthias, E-mail: maer@ethz.ch; Meier, Beat H., E-mail: beme@ethz.ch [ETH Zürich, Physical Chemistry (Switzerland)

    2015-10-15

    We discuss the optimum experimental conditions to obtain assignment spectra for solid proteins at magic-angle spinning (MAS) frequencies around 100 kHz. We present a systematic examination of the MAS dependence of the amide proton T{sub 2}′ times and a site-specific comparison of T{sub 2}′ at 93 kHz versus 60 kHz MAS frequency. A quantitative analysis of transfer efficiencies of building blocks, as they are used for typical 3D experiments, was performed. To do this, we compared dipolar-coupling and J-coupling based transfer steps. The building blocks were then combined into 3D experiments for sequential resonance assignment, where we evaluated signal-to-noise ratio and information content of the different 3D spectra in order to identify the best assignment strategy. Based on this comparison, six experiments were selected to optimally assign the model protein ubiquitin, solely using spectra acquired at 93 kHz MAS. Within 3 days of instrument time, the required spectra were recorded from which the backbone resonances have been assigned to over 96 %.

  4. The Evolution of the MasAgro Hubs: Responsiveness and Serendipity as Drivers of Agricultural Innovation in a Dynamic and Heterogeneous Context

    Science.gov (United States)

    Camacho-Villa, Tania Carolina; Almekinders, Conny; Hellin, Jon; Martinez-Cruz, Tania Eulalia; Rendon-Medel, Roberto; Guevara-Hernández, Francisco; Beuchelt, Tina D.; Govaerts, Bram

    2016-01-01

    Purpose: Little is known about effective ways to operationalize agricultural innovation processes. We use the MasAgro program in Mexico (which aims to increase maize and wheat productivity, profitability and sustainability), and the experiences of middle level "hub managers", to understand how innovation processes occur in heterogeneous…

  5. KrasMAS: Implementation of a nuclear material computerized accounting system at the Mining and Chemical Combine through the Russian/US cooperative MPC and A program

    International Nuclear Information System (INIS)

    Dorofeev, K.V.; Zhidkov, V.V.; Martinez, B.J.; Perry, R.T.; Scott, S.C.

    1998-01-01

    The Russian/US Mining and Chemical Combine (Gorno-Kimichesky Kombinat, GKhK, also referred to as Krasnoyarsk-26) Material Protection, Control and Accounting (MPC and A) project was initiated in June 1996. A critical component of the ongoing cooperative MPC and A enhancements at the GKhK is the implementation of a computerized nuclear material control and accountability (MC and A) system. This system must meet the MC and A requirements of the GKhK by integrating the information generated by numerous existing and new MC and A components in place at the GKhK (e.g., scales, bar-code equipment, NDA measurement systems). During the first phase of this effort, the GKhK adapted CoreMAS (developed at Los Alamos National Laboratory) for use in the PuO 2 storage facility. This included formulation of Web-based user interfaces for plant personnel, Russification of the existing user interface, and at the functional level, modification of the CoreMAS stored procedures. The modified system is referred to as KrasMAS and builds upon completed work on CoreMAS. Ongoing efforts include adding GKhK specific report forms and expanding the functionality of the system for implementation at the radiochemical processing and reactor plants of the GKhK. Collaborations with other Russian facilities for appropriate parts of these efforts will be pursued

  6. Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells.

    Science.gov (United States)

    Gatticchi, Leonardo; Cerra, Bruno; Scarpelli, Paolo; Macchioni, Lara; Sebastiani, Bartolomeo; Gioiello, Antimo; Roberti, Rita

    2017-09-01

    Sterol intermediates of the cholesterol biosynthetic pathway have drawn attention for novel biological activities. Follicular fluid meiosis activating sterol (FF-MAS) is a LXRα ligand and a potential modulator of physiologic processes regulated by nuclear receptors, such as lipid homeostasis and cell proliferation. In this work, we established a model to selectively accumulate FF-MAS in HepG2 cells, by using a combination of the inhibitors AY9944 and 17-hydroxyprogesterone to block C14-sterol reductases and the downstream C4-demethylase complex. We investigated the effects produced by altered levels of cholesterol biosynthesis intermediates, in order to dissect their influence on LXRα signaling. In particular, endogenously accumulated FF-MAS was able to modulate the expression of key genes in cholesterol metabolism, to activate LXRα nuclear signaling resulting in increased lipogenesis, and to inhibit HepG2 cells proliferation. Moreover, a fluorescent ester derivative of FF-MAS localized in nuclear lipid droplets, suggesting a role for these organelles in the storage of signaling lipids interacting with nuclear partners. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. KrasMAS: Implementation of a nuclear material computerized accounting system at the Mining and Chemical Combine through the Russian/US cooperative MPC and A program

    Energy Technology Data Exchange (ETDEWEB)

    Dorofeev, K.V.; Zhidkov, V.V. [Mining and Chemical Combine, Zheleznogorsk (Russian Federation); Martinez, B.J.; Perry, R.T.; Scott, S.C. [Los Alamos National Lab., NM (United States)

    1998-12-31

    The Russian/US Mining and Chemical Combine (Gorno-Kimichesky Kombinat, GKhK, also referred to as Krasnoyarsk-26) Material Protection, Control and Accounting (MPC and A) project was initiated in June 1996. A critical component of the ongoing cooperative MPC and A enhancements at the GKhK is the implementation of a computerized nuclear material control and accountability (MC and A) system. This system must meet the MC and A requirements of the GKhK by integrating the information generated by numerous existing and new MC and A components in place at the GKhK (e.g., scales, bar-code equipment, NDA measurement systems). During the first phase of this effort, the GKhK adapted CoreMAS (developed at Los Alamos National Laboratory) for use in the PuO{sub 2} storage facility. This included formulation of Web-based user interfaces for plant personnel, Russification of the existing user interface, and at the functional level, modification of the CoreMAS stored procedures. The modified system is referred to as KrasMAS and builds upon completed work on CoreMAS. Ongoing efforts include adding GKhK specific report forms and expanding the functionality of the system for implementation at the radiochemical processing and reactor plants of the GKhK. Collaborations with other Russian facilities for appropriate parts of these efforts will be pursued.

  8. Procyanidins in fruit from Sour cherry (Prunus cerasus) differ strongly in chainlength from those in Laurel cherry (Prunus lauracerasus) and Cornelian cherry (Cornus mas)

    NARCIS (Netherlands)

    Capanoglu, E.; Boyacioglu, D.; Vos, de R.C.H.; Hall, R.D.; Beekwilder, M.J.

    2011-01-01

    Sour cherry (Prunus cerasus), Laurel cherry (Prunus lauracerasus), and Cornelian cherry (Cornus mas) fruits are widely used in Turkey, both as food and as traditional medicines. The phytochemical composition and antioxidant capacities of these three cherry types were compared. Fruit flesh was

  9. Uji selektivitas ekstrak etil asetat (EtOAc biji putat air (Barringtonia racemosa terhadap keong mas (Pomacea canaliculata dan ikan lele lokal (Clarias batrachus

    Directory of Open Access Journals (Sweden)

    Musri Musman

    2012-04-01

    Full Text Available Penelitian ini bertujuan untuk menentukan selektivitas ekstrak etil asetat (EtOAc biji putat air (Barringtonia racemosa dalam pengendalian hama keong mas (Pomacea canaliculata yang dibandingkan terhadap ikan lele lokal (Clarias batrachus. Penelitian dilakukan di Laboratorium Kimia Laut Jurusan Ilmu Kelautan Koordinatorat Kelautan dan Perikanan dan Laboratorium Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Syiah Kuala dari bulan Juni sampai Juli 2011. Serbuk biji putat air diekstraksi berdasarkan kepolarannya secara berurutan, yaitu diklorometana, etil asetat, dan metanol. Pada penelitian ini digunakan ekstrak etil asetat dari simplisia. Penelitian ini dirancang dengan lima perlakuan konsentrasi (25, 50, 100, 200, dan 400 ppm. Masing – masing sebanyak 10 individu organisme uji (ikan lele lokal, keong mas digunakan pada tiap perlakuan. Tiap perlakuan dilakukan tiga kali ulangan. Ekstrak biji putat air dipajan ke dalam aquarium pengujian. Data hasil pengamatan mortalitas organisme uji dianalisis dengan program Trimmed Spearman Karber (TSK version 1.5. Nilai selektivitas dihitung berdasarkan harga LC50 yang diperoleh dari program TSK. Hasil penelitian menunjukkan bahwa (1 LC50 ekstrak biji putat air terhadap keong mas adalah 25,00 ppm dan LC50 ekstrak biji putat air terhadap lele lokal adalah 87,06 ppm. (2 selektivitas ekstrak biji putat air sebagai antimoluska keong mas terhadap ikan lele lokal adalah 3,48.

  10. Characteristics and Sampling Efficiencies of Two Impactor Bioaerosol Samplers: MAS-100(Registered) (Microbial Air Monitoring System) and Single-Stage Andersen Viable Microbial Samplers

    National Research Council Canada - National Science Library

    Hottell, K

    2004-01-01

    .... A petri dish with agar is used as the impaction surface for these samplers. The MAS-l00 is a single-stage impactor that aspirates air through a 400-hole perforated entry plate onto an agar plate at an airflow rate of 100 L/min...

  11. A Bio-Economic Case Study of Canadian Honey Bee (Hymenoptera: Apidae) Colonies: Marker-Assisted Selection (MAS) in Queen Breeding Affects Beekeeper Profits.

    Science.gov (United States)

    Bixby, Miriam; Baylis, Kathy; Hoover, Shelley E; Currie, Rob W; Melathopoulos, Andony P; Pernal, Stephen F; Foster, Leonard J; Guarna, M Marta

    2017-06-01

    Over the past decade in North America and Europe, winter losses of honey bee (Hymenoptera: Apidae) colonies have increased dramatically. Scientific consensus attributes these losses to multifactorial causes including altered parasite and pathogen profiles, lack of proper nutrition due to agricultural monocultures, exposure to pesticides, management, and weather. One method to reduce colony loss and increase productivity is through selective breeding of queens to produce disease-, pathogen-, and mite-resistant stock. Historically, the only method for identifying desirable traits in honey bees to improve breeding was through observation of bee behavior. A team of Canadian scientists have recently identified markers in bee antennae that correspond to behavioral traits in bees and can be tested for in a laboratory. These scientists have demonstrated that this marker-assisted selection (MAS) can be used to produce hygienic, pathogen-resistant honey bee colonies. Based on this research, we present a beekeeping case study where a beekeeper's profit function is used to evaluate the economic impact of adopting colonies selected for hygienic behavior using MAS into an apiary. Our results show a net profit gain from an MAS colony of between 2% and 5% when Varroa mites are effectively treated. In the case of ineffective treatment, MAS generates a net profit benefit of between 9% and 96% depending on the Varroa load. When a Varroa mite population has developed some treatment resistance, we show that MAS colonies generate a net profit gain of between 8% and 112% depending on the Varroa load and degree of treatment resistance. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America.

  12. The ACE-2/Ang1-7/Mas cascade enhances bone structure and metabolism following angiotensin-II type 1 receptor blockade.

    Science.gov (United States)

    Abuohashish, Hatem M; Ahmed, Mohammed M; Sabry, Dina; Khattab, Mahmoud M; Al-Rejaie, Salim S

    2017-07-15

    The renin angiotensin system (RAS) regulates numerous systemic functions and is expressed locally in skeletal tissues. Angiotensin1-7 (Ang1-7) is a beneficial member of the RAS, and the therapeutic effects of a large number of angiotensin receptors blockers (ARBs) are mediated by an Ang1-7-dependent cascade. This study examines whether the reported osteo-preservative effects of losartan are mediated through the angiotensin converting enzyme2 (ACE-2)/Ang1-7/Mas pathway in ovariectomized (OVX) rats. Sham and OVX animals received losartan (10mg/kg/d p.o.) for 6 weeks. A specific Mas receptor blocker (A-779) was delivered via mini-osmotic pumps during the losartan treatment period. Serum and urine bone metabolism biomarker levels were measured. Bone trabecular and cortical morphometry were quantified in distal femurs, whereas mineral contents were estimated in ashed bones, serum and urine. Finally, the expression of RAS components, the receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG) was determined. Losartan significantly improved the elevated bone metabolism marker levels and altered trabecular and cortical structures in OVX animals, and restored normal urinary and skeletal mineral levels. Mas receptor inhibition significantly abolished all osteo-protective effects of losartan and enhanced the deleterious effects of OVX. Losartan enhanced OVX-induced up-regulation of ACE-1, AngII, angiotensin type 1 (AT 1 ) receptor and RANKL expression, and increased ACE-2, Ang1-7, Mas and OPG expression in OVX animals. However, A-779 significantly eradicated the effects of losartan on RAS components and RANKL/OPG expression. Thus, Ang1-7 are involved in the osteo-preservative effects of losartan via Mas receptor, which may add therapeutic value to this well-known antihypertensive agent. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Mas-Related Gene (Mrg C Activation Attenuates Bone Cancer Pain via Modulating Gi and NR2B.

    Directory of Open Access Journals (Sweden)

    Yu'e Sun

    Full Text Available This study is to investigate the role of Mas-related gene (Mrg C in the pathogenesis and treatment of bone cancer pain (BCP.BCP mouse model was established by osteosarcoma cell inoculation. Pain-related behaviors were assessed with the spontaneous lifting behavior test and mechanical allodynia test. Expression levels of MrgC, Gi, and NR2B in the spinal cord were detected with Western blot analysis and immunohistochemistry.Pain-related behavior tests showed significantly increased spontaneous flinches (NSF and decreased paw withdrawal mechanical threshold (PWMT in mouse models of BCP. Western blot analysis showed that, compared with the control group and before modeling, all the expression levels of MrgC, Gi, and NR2B in the spinal cord of BCP mice were dramatically elevated, which were especially increased at day 7 after operation and thereafter, in a time-dependent manner. Moreover, the treatment of MrgC agonist BAM8-22 significantly up-regulated Gi and down-regulated NR2B expression levels, in the spinal cord of BCP mice, in a time-dependent manner. On the other hand, anti-MrgC significantly down-regulated Gi expression, while dramatically up-regulated NR2B expression, in the BCP mice. Similar results were obtained from the immunohistochemical detection. Importantly, BAM8-22 significantly attenuated the nociceptive behaviors in the BCP mice.Our results indicated the MrgC-mediated Gi and NR2B expression alterations in the BCP mice, which might contribute to the pain hypersensitivity. These findings may provide a novel strategy for the treatment of BCP in clinic.

  14. Oocyte maturation. Basic and clinical aspects of in vitro maturation (IVM) with special emphasis of the role of FF-MAS.

    Science.gov (United States)

    Grøndahl, Christian

    2008-02-01

    In Vitro maturation (IVM) of human oocytes is an emerging infertility treatment with great promise. To be successful this future assisted reproductive technology must entail both nuclear and cytoplasmic maturation of the oocytes and give rise to human embryos that have the same developmental potential as embryos resulting from the golden standard of human IVF. The aspiration of immature oocytes from small to medium size antral follicles followed by their maturation In Vitro present an attractive alternative to the hormonal stimulation of patients in In Vitro fertilization (IVF) treatment, since administration of exogenous hormones is a costly treatment and may cause severe health problems. Of the long list of side effect and health concern ovarian hyper-stimulation syndrome (OHSS) is by far the most severe although long term effect on cancer prevalence is another concern. Another potential group of patients that could benefit from future IVM treatments are the young women undergoing anticancer therapy (radiation- or chemotherapy). Thus, ovarian and oocyte cryopreservation techniques are emerging, however such treatments can only be fully realized when IVM becomes an efficient means of obtaining healthy birth. At present, the In Vitro maturation techniques are highly successful in mice, variable successful in domestic species and still regarded experimental in the human clinic due to suboptimal fertilization rates and embryo quality. This review discusses comparative studies of the processes of oocyte maturation In Vivo and In Vitro, in various mammalian species including human. Among the substances that have been reported to influence oocyte maturation there is an interesting endogenous signaling molecule: FF-MAS (4,4-dimethyl-5 alpha-cholest-8,14,24-trien-3 beta -ol), an intermediate in the cholesterol biosynthetic pathway present in all cells. This review gives special focus to FF-MAS, the effect seen in animal and human studies so far and its potential use in

  15. Intrarenal Mas and AT1 receptors play a role in mediating the excretory actions of renal interstitial angiotensin-(1-7) infusion in anaesthetized rats.

    Science.gov (United States)

    O'Neill, Julie; Healy, Vincent; Johns, Edward J

    2017-12-01

    What is the central question of this study? Dietary sodium manipulation alters the magnitude of angiotensin-(1-7) [Ang-(1-7)]-induced natriuresis. The present study sought to determine whether this was related to relative changes in the activity of intrarenal Mas and/or AT 1 receptors. What is the main finding and its importance? Angiotensin-(1-7)-induced diuresis and natriuresis is mediated by intrarenal Mas receptors. However, intrarenal AT 1 receptor blockade also had an inhibitory effect on Ang-(1-7)-induced natriuresis and diuresis. Thus, Ang-(1-7)-induced increases in sodium and water excretion are dependent upon functional Mas and AT 1 receptors. We investigated whether angiotensin-(1-7) [Ang-(1-7)]-induced renal haemodynamic and excretory actions were solely dependent upon intrarenal Mas receptor activation or required functional angiotensin II type 1 (AT 1 ) receptors. The renin-angiotensin system was enhanced in anaesthetized rats by prior manipulation of dietary sodium intake. Angiotensin-(1-7) and AT 1 and Mas receptor antagonists were infused into the kidney at the corticomedullary border. Mas receptor expression was measured in the kidney. Mean arterial pressure, urine flow and fractional sodium excretion were 93 ± 4 mmHg, 46.1 ± 15.7 μl min -1  kg -1 and 1.4 ± 0.3%, respectively, in the normal-sodium group and 91 ± 2 mmHg, 19.1 ± 3.3 μl min -1  kg -1 and 0.7 ± 0.2%, respectively, in the low-sodium group. Angiotensin-(1-7) infusion had no effect on mean arterial pressure in rats receiving a normal-sodium diet but decreased it by 4 ± 5% in rats receiving a low-sodium diet (P < 0.05). Interstitial Ang-(1-7) infusion increased urine flow twofold and fractional sodium excretion threefold (P < 0.05) in rats receiving a normal-sodium diet and to a greater extent, approximately three- and fourfold, respectively, in rats receiving the low-sodium diet (both P < 0.05). Angiotensin-(1-7)-induced increases in urine flow and

  16. The metabolic profile of lemon juice by proton HR-MAS NMR: the case of the PGI Interdonato Lemon of Messina.

    Science.gov (United States)

    Cicero, Nicola; Corsaro, Carmelo; Salvo, Andrea; Vasi, Sebastiano; Giofré, Salvatore V; Ferrantelli, Vincenzo; Di Stefano, Vita; Mallamace, Domenico; Dugo, Giacomo

    2015-01-01

    We have studied by means of High Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) the metabolic profile of the famous Sicilian lemon known as 'Interdonato Lemon of Messina PGI'. The PGI Interdonato Lemon of Messina possesses high organoleptic and healthy properties and is recognised as one of the most nutrient fruits. In particular, some of its constituents are actively studied for their chemo-preventive and therapeutic properties. In this paper, we have determined by means of HR-MAS NMR spectroscopy the molar concentration of the main metabolites constituent the juice of PGI Interdonato Lemon of Messina in comparison with that of the not-PGI Interdonato Lemon of Turkey. Our aim is to develop an analytical technique, in order to determine a metabolic fingerprint able to reveal commercial frauds in national and international markets.

  17. “Estado Nación laico y secularización masónica en México”

    Directory of Open Access Journals (Sweden)

    Carlos Francisco Martínez Moreno

    2011-01-01

    Full Text Available Este artículo busca mostrar cómo y porqué los masones practicantes del Rito Nacional Mexicano en el siglo XIX secularizaron su tradición para responder a sus compromisos sociales, patrióticos, liberales y democráticos. Además, muestra cómo ellos sustituyeron La Biblia por la Constitución Política de los Estados Unidos Mexicanos en sus juramentos masónicos, en un contexto social en el que jurarla se consideraba un anatema por el Papa Pío IX y el clero católico, y en un contexto masónico adverso en el que sustituir el Libro de la Ley y participar en la política como masones era contravenir la tradición especulativa londinense.

  18. Solid-state 51V MAS NMR spectroscopy determines component concentration and crystal phase in co-crystallised mixtures of vanadium complexes

    DEFF Research Database (Denmark)

    Nielsen, Ulla Gro; Hazell, Alan Charles; Skibsted, Jørgen Bengaard

    2010-01-01

    The oxo-peroxo-vanadium(v) and dioxo-vanadium(v) complexes of N,N-bis(2-pyridylmethyl)glycinate (bpg(-)), VO(O-2)(bpg) (1) and V(O)(2)(bpg) (2) co-crystallize in variable ratios in an anhydrous and a dihydrate phase with the overall formulation 1(x)2(1-x)center dot nH(2)O, n = 0 or 2, where 0 ... oxide ligand (O2-) in the same position. Characteristic chemical shift differences...... for the vanadium atoms of the two complexes mean that V-51 solution state and MAS NMR spectroscopy can be used to determine the concentration of 1 and 2 in bulk samples. Significantly, however, V-51 MAS NMR spectroscopy also reports on the identity of the crystal phase. This is possible because the isotropic V-51...

  19. Un lote de armamento ibérico procedente de la necrópolis del Mas de Barberán (Nogueruelas, Teruel

    Directory of Open Access Journals (Sweden)

    Izquierdo Peraile, Isabel

    1999-12-01

    Full Text Available In this paper we publish an Ibenan set of weapons -swords, lances and dagger essentially-, coming from the cemetery of the settlement so-called Mas de Barberán (Nogueruelas, Teruel. An anthropomorphic stele with an inscription recently studied is associated to the same site. This stele represents an armed with disk-cuirass masculine personage.

    En este trabajo presentamos un lote inédito de armamento ibérico espadas, lanzas y puñal esencialmente procedente de la necrópolis correspondiente al poblado del Mas de Barberán (Nogueruelas, Teruel. Al mismo yacimiento se asocia la estela antropomorfa con inscripción que representa un personaje masculino armado con disco-coraza, recientemente estudiada.

  20. Hyperspectral Microwave Atmospheric Sounder (HyMas) - New Capability in the CoSMIR-CoSSIR Scanhead

    Science.gov (United States)

    Hilliard, L. M.; Racette, P. E.; Blackwell, W.; Galbraith, C.; Thompson, E.

    2015-01-01

    Lincoln Laboratory and NASA's Goddard Space Flight Center have teamed to re-use an existing instrument platform, the CoSMIRCoSSIR system for atmospheric sounding, to develop a new capability in hyperspectral filtering, data collection, and display. The volume of the scanhead accomodated an intermediate frequency processor(IFP), that provides the filtering and digitization of the raw data and the interoperable remote component (IRC) adapted to CoSMIR, CoSSIR, and HyMAS that stores and archives the data with time tagged calibration and navigation data.The first element of the work is the demonstration of a hyperspectral microwave receiver subsystem that was recently shown using a comprehensive simulation study to yield performance that substantially exceeds current state-of-the-art. Hyperspectral microwave sounders with 100 channels offer temperature and humidity sounding improvements similar to those obtained when infrared sensors became hyperspectral, but with the relative insensitivity to clouds that characterizes microwave sensors. Hyperspectral microwave operation is achieved using independent RF antennareceiver arrays that sample the same areavolume of the Earths surfaceatmosphere at slightly different frequencies and therefore synthesize a set of dense, finely spaced vertical weighting functions. The second, enabling element of the proposal is the development of a compact 52-channel Intermediate Frequency processor module. A principal challenge in the development of a hyperspectral microwave system is the size of the IF filter bank required for channelization. Large bandwidths are simultaneously processed, thus complicating the use of digital back-ends with associated high complexities, costs, and power requirements. Our approach involves passive filters implemented using low-temperature co-fired ceramic (LTCC) technology to achieve an ultra-compact module that can be easily integrated with existing RF front-end technology. This IF processor is universally

  1. Hydrogen-bond interactions in organically-modified polysiloxane networks studied by 1D and 2D CRAMPS and double-quantum 1H MAS NMR

    Czech Academy of Sciences Publication Activity Database

    Brus, Jiří; Dybal, Jiří

    2002-01-01

    Roč. 35, č. 27 (2002), s. 10038-10047 ISSN 0024-9297 R&D Projects: GA ČR GA203/98/P290; GA AV ČR KSK4050111 Institutional research plan: CEZ:AV0Z4050913 Keywords : Hydrogen bonding * polysiloxane * 1H MAS NMR Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.751, year: 2002

  2. LC/ESI-MS n and 1H HR-MAS NMR analytical methods as useful taxonomical tools within the genus Cystoseira C. Agardh (Fucales; Phaeophyceae).

    Science.gov (United States)

    Jégou, Camille; Culioli, Gérald; Kervarec, Nelly; Simon, Gaëlle; Stiger-Pouvreau, Valérie

    2010-12-15

    Species of the genus Cystoseira are particularly hard to discriminate, due to the complexity of their morphology, which can be influenced by their phenological state and ecological parameters. Our study emphasized on the relevance of two kinds of analytical tools, (1) LC/ESI-MS(n) and (2) (1)H HR-MAS NMR, also called in vivo NMR, to identify Cystoseira specimens at the specific level and discuss their taxonomy. For these analyses, samples were collected at several locations in Brittany (France), where Cystoseira baccata, C. foeniculacea, C. humilis, C. nodicaulis and C. tamariscifolia were previously reported. To validate our chemical procedure, the sequence of the ITS2 has been obtained for each species to investigate their phylogenetic relationships at a molecular level. Our study highlighted the consistency of the two physico-chemical methods, compared to "classical" molecular approach, in studying taxonomy within the genus Cystoseira. Especially, LC/ESI-MS(n) and phylogenetic analyses converged into the discrimination of two taxonomical groups among the 5 species. The occurrence of some specific signals in the (1)H HR-MAS NMR spectra and/or some characteristic chemical compounds during LC/ESI-MS(n) analysis could be regarded as discriminating factors. LC/ESI-MS(n) and (1)H HR-MAS NMR turned out to be two relevant and innovative techniques to discriminate taxonomically this complex genus. Copyright © 2010 Elsevier B.V. All rights reserved.

  3. Jauniešu bezdarba problēmas un to risināšanas iespēja Latvijā.

    OpenAIRE

    Ģērmane, Ieva

    2017-01-01

    Maģistra darba tēmas “Jauniešu bezdarba problēmas un to risināšanas iespējas Latvijā“ aktualitāti nosaka tas, ka jauniešu (15-24 gadi) bezdarba līmenis Latvijā pēc piedzīvotās ekonomiskās krīzes saglabājas augstā līmenī, gandrīz divas reizes pārsniedzot kopējo (15-74 gadi) bezdarba rādītāju. Darba mērķis ir pamatojoties uz zinātniskās literatūras analīzi novērtēt jauniešu bezdarba izplatību un ar to saistītās problēmas Latvijā, atklāt būtiskākos jauniešu bezdarbu ietekmējošos faktorus, izvēr...

  4. UJI APLIKASI VAKSIN HYDROVAC UNTUK PENCEGAHAN PENYAKIT MERAH PADA IKAN MAS (Cyprinus carpio DAN GURAME (Osphronemus gouramy DI BALAI BENIH IKAN PANDAK KABUPATEN BANYUMAS

    Directory of Open Access Journals (Sweden)

    Indrawati Indrawati

    2009-06-01

    Full Text Available Uji aplikasi vaksin ini bertujuan untuk mengetahui pengaruh pemberian vaksin hydrovac terhadap perkembangan kesehatan ikan mas dan gurami, serta mendapatkan informasi tentang cara pengendalian, melalui tindakan pencegahan ikan air tawar yang terserang wabah penyakit Aeromonas hydrophila. Sebanyak 39 ekor ikan mas (Cyprinus carpio dengan bobot rata-rata 1 kg dan panjang rata-rata 30 cm dan108 ekor ikan gurami (Osphronemus gouramy L. dengan bobot rata-rata 250 g dan panjang rata-rata 10 cm yang berasal dari Balai Benih Ikan (BBI Pandak Kabupaten Banyumas, digunakan sebagai ikan uji. Vaksin yang digunakan adalah “vaksin hydrovac” yang diproduksi oleh Laboratorium Patologi Ikan. Balai Riset Perikanan Budidaya Air Tawar, Bogor. Vaksin diaplikasikan dengan cara dicampur pelet dengan dosis 2--3 mL per kilogram bobot badan ikan yang diberikan selama 5--7 hari berturut-turut dan setelah satu bulan kemudian dilakukan vaksinasi ulangan (booster terhadap ikan yang telah divaksin dengan cara yang sama. Hasil uji menunjukkan bahwa ikan baik ikan mas maupun gurame yang divaksin menunjukkan angka sintasan yang cukup tinggi apabila dibandingkan dengan ikan yang tidak divaksin. Mortalitas ikan uji yang tidak divaksin terjadi mulai minggu ke-5 dan ke-6.

  5. Sensitivity of Neurospora crassa to a Marine-Derived Aspergillus tubingensis Anhydride Exhibiting Antifungal Activity That Is Mediated by the MAS1 Protein

    Directory of Open Access Journals (Sweden)

    Liat Koch

    2014-09-01

    Full Text Available The fungus Aspergillus tubingensis (strain OY907 was isolated from the Mediterranean marine sponge Ircinia variabilis. Extracellular extracts produced by this strain were found to inhibit the growth of several fungi. Among the secreted extract components, a novel anhydride metabolite, tubingenoic anhydride A (1 as well as the known 2-carboxymethyl-3-hexylmaleic acid anhydride, asperic acid, and campyrone A and C were purified and their structure elucidated. Compound 1 and 2-carboxymethyl-3-hexylmaleic acid anhydride inhibited Neurospora crassa growth (MIC = 330 and 207 μM, respectively and affected hyphal morphology. We produced a N. crassa mutant exhibiting tolerance to 1 and found that a yet-uncharacterized gene, designated mas-1, whose product is a cytosolic protein, confers sensitivity to this compound. The ∆mas-1 strain showed increased tolerance to sublethal concentrations of the chitin synthase inhibitor polyoxin D, when compared to the wild type. In addition, the expression of chitin synthase genes was highly elevated in the ∆mas-1 strain, suggesting the gene product is involved in cell wall biosynthesis and the novel anhydride interferes with its function.

  6. Saline lavage with substitution of bovine surfactant in term neonates with meconium aspiration syndrome (MAS) transferred for extracorporeal membrane oxygenation (ECMO): a pilot study

    Science.gov (United States)

    Möller, Jens C; Kohl, Martina; Reiss, Irwin; Diederich, Wiebke; Nitsche, Esther M; Göpel, Wolfgang; Gortner, Ludwig

    1999-01-01

    Background: Meconium aspiration syndrome (MAS) is still a condition associated with a high mortality, and many patients require extracorporeal membrane oxygenation (ECMO) as rescue therapy. Beneficial effects of surfactant and perflubron lavage have been reported. However, pure surfactant supplementation has not been proven to be beneficial in the most severe forms of MAS. This study was performed to demonstrate an improvement in oxygenation in neonates transferred for ECMO and fulfilling ECMO criteria with a saline lavage and surfactant resupplementation. Methods: Twelve newborns with MAS [gestational age 36–40 weeks, mean birth weight 3200 g, age 4–16 h, oxygenation index (OI) > 40] transferred for ECMO therapy were treated with saline lavage (5–10 cm3/kg body weight, as long as green colored retrieval was observed) and resupplementation with bovine surfactant (Alveofact, Boehringer, Ingelheim, Germany). The OI at admission and 3 h after this procedure was compared using the t-test for paired samples. ECMO was available as rescue therapy at all times. Results: The OI decreased from 49.4 (SD ± 13.3) to 27.4 (SD ± 7.3), P meconium by extensive lavage is feasible as long as 16 h after birth even in infants considered for ECMO therapy; it might reduce the necessity of ECMO. PMID:11056719

  7. Selektivitas fraksi R f < 0,5 ekstrak etil asetat (EtOAc biji putat air (Barringtonia racemosaterhadap keong mas (Pomacea canaliculata dan ikan lele lokal (Clarias batrachus

    Directory of Open Access Journals (Sweden)

    Musri Musman

    2012-08-01

    Full Text Available Penelitian untuk mengetahui selektivitas fraksi Rf < 0,5 ekstrak EtOAc biji putat air (Barringtonia racemosa terhadap keong mas (Pomacea canaliculata dan lele lokal (Clarias batrachus telah dilakukan pada bulan Februari 2012 di Laboratorium Kimia Fakultas Keguruan dan Ilmu Pendidikan dan Laboratorium Kimia Laut Koordinatorat Kelautan dan Perikanan Universitas Syiah Kuala. Kromatografi lapis tipis digunakan sebagai teknik pemisahan komponen senyawaan dalam ekstrak cuplikan, dan pengujian keaktifan biologi didasarkan pada kaedah yang dianjurkan oleh FAO. Data mortalitas keong mas dan lele lokal yang diperoleh karena pemberian fraksi Rf < 0,5 ekstrak EtOAc biji B. racemosa dianalisa dengan program Probit, dan harga selektivitas (S diolah berdasarkan formula Feng dan Wang. Harga LC50 fraksi Rf< 0,5 ekstrak EtOAc biji B. racemosa terhadap P. canaliculata dan C.batracus masing-masing adalah 29,26 ppm dan 44,47 ppm. Nilai selektivitas fraksi Rf< 0,5 ekstrak EtOAc biji B.racemosa terhadap organisme uji adalah 1.51. Penelitian ini menunjukkan bahwa fraksi Rf < 0,5 ekstrak EtOAc biji putat air memiliki bioaktif sebagai moluskosida keong mas.

  8. Chemometric analysis applied in 1H HR-MAS NMR and FT-IR data for chemotaxonomic distinction of intact lichen samples

    International Nuclear Information System (INIS)

    Alcantara, Glaucia Braz; Honda, Neli Kika; Castro Ferreira, Marcia Miguel; Ferreira, Antonio Gilberto

    2007-01-01

    This paper describes the potentiality of chemometric analysis applied in 1 H HR-MAS NMR and FT-IR data for lichen chemotaxonomic investigations. Lichens present a difficult morphologic differentiation and the chemical analyses are frequently employed for their taxonomic classification, mainly due to the secondary metabolites to be relatively constant for these organisms. The lichen chemotaxonomic classification is usually carried out by color reactions, chromatography, fluorescence and mass spectrometry analysis, where the identification is obtained by one or more techniques. There are some papers which use the carbohydrate content in chemotaxonomy investigation. However, the majority of these techniques involve laborious and time consuming sample pre-treatment. This work focuses on application of 1 H high resolution magic angle spinning - nuclear magnetic resonance (HR-MAS NMR) and Fourier transform infrared (FT-IR) associated with chemometric analysis to intact samples. In comparison to other traditional techniques, 1 H HR-MAS NMR and FT-IR allied with chemometrics provided a fast and economic method for lichen chemotaxonomy. Both methods were useful for lichen analysis and permitted the satisfactory distinction among families, genera and species, although better results were achieved for FT-IR data

  9. Chemometric analysis applied in {sup 1}H HR-MAS NMR and FT-IR data for chemotaxonomic distinction of intact lichen samples

    Energy Technology Data Exchange (ETDEWEB)

    Alcantara, Glaucia Braz [Departamento de Quimica, Universidade Federal de Sao Carlos, P.O. Box 676, CEP 13565-905, Sao Carlos/SP (Brazil)]. E-mail: glabraz@yahoo.com.br; Honda, Neli Kika [Departamento de Quimica, Universidade Federal de Mato Grosso do Sul, P.O. Box 549, CEP 79070-900, Campo Grande/MS (Brazil); Castro Ferreira, Marcia Miguel [Instituto de Quimica, Universidade Estadual de Campinas, P.O. Box 6154, CEP 13084-971, Campinas/SP (Brazil); Ferreira, Antonio Gilberto [Departamento de Quimica, Universidade Federal de Sao Carlos, P.O. Box 676, CEP 13565-905, Sao Carlos/SP (Brazil)

    2007-07-09

    This paper describes the potentiality of chemometric analysis applied in {sup 1}H HR-MAS NMR and FT-IR data for lichen chemotaxonomic investigations. Lichens present a difficult morphologic differentiation and the chemical analyses are frequently employed for their taxonomic classification, mainly due to the secondary metabolites to be relatively constant for these organisms. The lichen chemotaxonomic classification is usually carried out by color reactions, chromatography, fluorescence and mass spectrometry analysis, where the identification is obtained by one or more techniques. There are some papers which use the carbohydrate content in chemotaxonomy investigation. However, the majority of these techniques involve laborious and time consuming sample pre-treatment. This work focuses on application of {sup 1}H high resolution magic angle spinning - nuclear magnetic resonance (HR-MAS NMR) and Fourier transform infrared (FT-IR) associated with chemometric analysis to intact samples. In comparison to other traditional techniques, {sup 1}H HR-MAS NMR and FT-IR allied with chemometrics provided a fast and economic method for lichen chemotaxonomy. Both methods were useful for lichen analysis and permitted the satisfactory distinction among families, genera and species, although better results were achieved for FT-IR data.

  10. Reklāmas kampaņas izstrādāšana, īstenošana un komunikācijas problēmas: kinoteātra "Cinamon" gadījums (2008. gada oktobris - 2009. gada februāris)

    OpenAIRE

    Zvejniece, Zane

    2009-01-01

    Bakalaura darba tēma ir „Reklāmas kampaņas izstrādāšana, īstenošana un komunikācijas problēmas: kinoteātra „Cinamon” gadījums (2008. gada oktobris – 2009. gada februāris)” Kinoteātris „Cinamon” atvērts 2008. gada novembrī. Otrā daudzzāļu kinoteātra ienākšana Latvijā bija nozīmīgs notikums. Ienākot tirgū, liela nozīme ir rūpīgi izplānotai reklāmas kampaņai. Darbā izvirzīta hipotēze: ienākot tirgū un veidojot reklāmas kampaņu, kinoteātris „Cinamon” saskārās ar komunikācijas problēmām, ka...

  11. Local environments and lithium adsorption on the iron oxyhydroxides lepidocrocite (gamma-FeOOH) and goethite (alpha-FeOOH): A 2H-2 and 7Li solid-state MAS NMR study

    DEFF Research Database (Denmark)

    Nielsen, Ulla Gro; Grey, Clare P.; Paik, Jonkim

    2008-01-01

    2H and 7LiMAS NMR spectroscopy techniques were applied to study the local surface and bulk environments of iron oxyhydroxide lepiclocrocite (gamma-FeOOH). 2H variable-temperature (VT) MAS NMR experiments were performed, showing the presence of short-range, strong antiferromagnetic correlations......, even at temperatures above the Neel temperature, TN, 77 K. The formation of a Li+ inner-sphere complex on the surface of lepiclocrocite was confirmed by the observation of a signal with a large 7Li hyperfine shift in the 7Li  MAS NMR spectrum. The effect of pH and relative humidity (RH...

  12. Biological response in various compartments of the rat lens after in vivo exposure to UVR-B analyzed by HR-MAS 1H NMR spectroscopy.

    Science.gov (United States)

    Tessem, May-Britt; Bathen, Tone F; Löfgren, Stefan; Saether, Oddbjørn; Mody, Vino; Meyer, Linda; Dong, Xiuqin; Söderberg, Per G; Midelfart, Anna

    2006-12-01

    The purpose of the present study was to investigate metabolic changes in different compartments of the rat lens (anterior, nuclear, posterior, and equatorial) after exposure to an acute double threshold dose of ultraviolet-B radiation (UVR-B) by using high-resolution magic angle spinning (HR-MAS) (1)H nuclear magnetic resonance (NMR) spectroscopy and pattern recognition (PR) METHODS: methods. One eye in each of 28 6-week-old female albino Sprague-Dawley rats was exposed to in vivo 7.5 kJ/m2 UVR-B for 15 minutes. The contralateral eye was left unexposed. One week after irradiation, all rats were killed, and both lenses were isolated. Each lens was cored by a trephine, and the cylinder was sliced into three portions (anterior, nuclear, and posterior). The lens material that remained after the coring process was analyzed as the equatorial region. Analysis of lens metabolism was performed by HR-MAS 1H NMR spectroscopy (14.1 T; Avance DRX600; Bruker BioSpin GmbH, Rheinstetten, Germany), and the metabolic profiles were statistically analyzed by the PR method of principal component analysis (PCA). Metabolic differences were detected among the compartments in the lens, both in samples from the contralateral nonexposed lenses and in samples from lenses exposed to in vivo UVR-B. In the rat lens, exposure to UVR-B caused changes in GSH, phosphocholine, myo-inositol, succinate, formate, and adenosine triphosphate (ATP)/adenosine diphosphate (ADP) and in levels of the amino acids phenylalanine, taurine, hypo-taurine, tyrosine, alanine, valine, isoleucine, and glutamate, that varied among lens compartments. HR-MAS 1H NMR spectroscopy, combined with PR methods (PCA), is effective for analysis of separate parts of the intact rat lens. To understand the biochemistry of the lens, it is important to divide the lens into sections, representing functionally and anatomically distinct compartments.

  13. Evidence for radiation induced crosslinking in polytetrafluoroethylene by means of high-resolution solid-state 19F high-speed MAS NMR

    International Nuclear Information System (INIS)

    Katoh, Etsuko; Sugisawa, Hisashi; Oshima, Akihiro; Tabata, Yoneho; Seguchi, Tadao; Yamazaki, Toshimasa

    1999-01-01

    Radiation effects on molecular structure of polytetrafluoroethylene (PTFE) were studied by high-resolution solid-state 19 F high speed magic angle spinning (HS MAS) NMR spectroscopy. Samples used for the NMR studies were prepared by electron beam irradiation of PTFE with a wide range of irradiation doses from 0.5-10 MGy in the molten state at 340 deg. C under oxygen-free atmosphere. While the non-irradiated PTFE displayed only an intense peak of the internal CF 2 , several new signals corresponding to CF 3 , CF 2 and CF groups were observed for the PTFE which was high temperature irradiated at 340 deg. C in oxygen-free atmosphere (hti-PTFE). Intensities of these new signals increased with an increase of irradiation dose. The present solid-state 19 F HS MAS NMR studies provide not only the first experimental evidence regarding the existence of crosslinking structure in hti-PTFE, directly detected as the CF signal, but also the crosslinking density which can be estimated from a proportion of the CF versus total fluorine signal intensities. The higher the irradiation dose, the higher the crosslinking density; hti-PTFE with 10 MGy contains one crosslinking site per approximately 24 CF 2 groups, while the hti-PTFE with 5 MGy contains one crosslinking site per approximately 36 CF 2 groups. Further, G value of crosslinking (G(x)) was estimated from the signal intensities of 19 F HS MAS NMR spectra. The highest G(x)-value, 1.85, was observed for the 2MGy hti-PTFE sample, suggesting that crosslinking of PTFE is formed most efficaciously with 2 MGy irradiation in the molten state at 340 deg. C under oxygen-free atmosphere

  14. Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: using in silico techniques to differentiate the three receptors.

    Directory of Open Access Journals (Sweden)

    Jeremy W Prokop

    Full Text Available The renin-angiotensin system is involved in multiple conditions ranging from cardiovascular disorders to cancer. Components of the pathway, including ACE, renin and angiotensin receptors are targets for disease treatment. This study addresses three receptors of the pathway: AT1, AT2, and MAS and how the receptors are similar and differ in activation by angiotensin peptides. Combining biochemical and amino acid variation data with multiple species sequence alignments, structural models, and docking site predictions allows for visualization of how angiotensin peptides may bind and activate the receptors; allowing identification of conserved and variant mechanisms in the receptors. MAS differs from AT1 favoring Ang-(1-7 and not Ang II binding, while AT2 recently has been suggested to preferentially bind Ang III. A new model of Ang peptide binding to AT1 and AT2 is proposed that correlates data from site directed mutagenesis and photolabled experiments that were previously considered conflicting. Ang II binds AT1 and AT2 through a conserved initial binding mode involving amino acids 111 (consensus 325 of AT1 (Asn interacting with Tyr (4 of Ang II and 199 and 256 (consensus 512 and 621, a Lys and His respectively interacting with Phe (8 of Ang II. In MAS these sites are not conserved, leading to differential binding and activation by Ang-(1-7. In both AT1 and AT2, the Ang II peptide may internalize through Phe (8 of Ang II propagating through the receptors' conserved aromatic amino acids to the final photolabled positioning relative to either AT1 (amino acid 294, Asn, consensus 725 or AT2 (138, Leu, consensus 336. Understanding receptor activation provides valuable information for drug design and identification of other receptors that can potentially bind Ang peptides.

  15. Uso del FitoMas-E® como atenuante del estrés salino (NaCl durante la emergencia y crecimiento inicial de Ocimum basilicum L.

    Directory of Open Access Journals (Sweden)

    D. Batista-Sánchez

    2015-01-01

    Full Text Available El uso de bioestimulantes vegetales estimula la emergencia y el crecimiento vegetal debido a que están compuestos por sustancias naturales como carbohidratos, péptidos de bajo peso molecular y aminoácidos, activadores de las funciones fisiológicas de las plantas, por lo que su aplicación permite un mejor aprovechamiento de los nutrientes y representa una opción para enfrentar problemas de estrés abiótico por salinidad. El objetivo de este estudio fue determinar el efecto del bioestimulante FitoMas-E® derivado de la caña de azúcar como atenuante de la salinidad en la emergencia y el crecimiento de plántulas de variedades de albahaca (Ocimum basilicum L. con respuesta diferencial al estrés por salinidad. Tres variedades de albahaca: Napoletano, Emily y Nufar se sometieron a cuatro concentraciones de NaCl (0, 50, 100 y 150 mM y cuatro dosis de FitoMas-E® (0, 0.5, 1.0 y 1.5 mL L-1 en un diseño completamente al azar con arreglo factorial con cuatro repeticiones. El trabajo se desarrolló en una estructura de malla sombra y las variables que se midieron fueron: porcentaje y tasa de emergencia, longitud de radícula, altura de la plántula, biomasa fresca y seca de radícula y de parte aérea. Los resultados evidenciaron que en condiciones de estrés salino (NaCl de moderado a severo, las variables disminuyeron significativamente. Largo de raíz, altura de planta y biomasa seca de raíz en 150 mM de NaCl fueron las más afectadas. Se observó que cuando se aplicó FitoMas-E® las plantas incrementaron significativamente sus valores en las variables, largo de raíz 32% y altura de planta 41%, lo que revela el efecto estimulante del FitoMas-E®, siendo 0.5 mL L-1 la dosis estimulante para la variedad Napoletano y 1.0 mL L-1 para la variedad Emily, aún y cuando se encontraban en condiciones de estrés salino hasta 100 mM de NaCl. Para la concentración de 150 mM se evidenció una afectación extrema para las variedades Emily y Nufar.

  16. A CRAMPS and 13C CP/MAS NMR examination of solid-solid transitions in n-Hexatriacontane (C36H74)

    Science.gov (United States)

    Stewart, Michael J.; Mathias, Lon J.

    1994-07-01

    The normal paraffins can undergo several transitions before melting and may thus serve as interesting model compounds for polyethylene, which also undergoes solid-solid transitions, the strongest and best-known being the so-called alpha transition. Our examination of n-Hexatriacontane (C36) has been greatly furthered by the use of the solid-state H-1 NMR technique known as CRAMPS (combined rotation and multiple pulse spectroscopy). This technique, combined with DSC and C-13 CP/MAS NMR, has allowed us to make tentative assignments for the molecular motions occurring at different temperatures below the melting point.

  17. Observation of immobile regions in natural rubber at ambient temperature by solid-state C-13 CP/MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Larsen, F.H.; Rasmussen, T.; Pedersen, Walther Batsberg

    1999-01-01

    Employing C-13 CP/MAS NMR spectroscopy, the existence of immobile regions in natural rubber (cis-1,4-polyisoprene) corresponding to a few percent of the monomer units has been detected at ambient temperature. For synthetic rubbers no immobile regions have been detected at all. Applying different ...... physical and chemical treatments to natural rubber it is shown that mastication, gamma-irradiation, and increasing the temperature, slightly above the ambient, reduce the amount of immobile regions. (C) 1999 Elsevier Science Ltd. All rights reserved....

  18. Investigating sorption on iron-oxyhydroxide soil minerals by solid-state NMR spectroscopy: a 6Li MAS NMR study of adsorption and absorption on goethite

    DEFF Research Database (Denmark)

    Nielsen, Ulla Gro; Paik, Younkee; Julmis, Keinia

    2005-01-01

    High-resolution 2H MAS NMR spectra can be obtained for nanocrystalline particles of goethite (alpha-FeOOH, particle size approximately 4-10 nm) at room temperature, facilitating NMR studies of sorption under environmentally relevant conditions. Li sorption was investigated as a function of pH, th...... on the goethite surface. Even larger Li hyperfine shifts (289 ppm) were observed for Li+-exchanged goethite, which contains lithium ions in the tunnels of the goethite structure, confirming the Li assignment of the 145 ppm Li resonance to the surface sites. Udgivelsesdato: 2005-Oct-6...

  19. Entrenamiento y fisiología del ejercicio en la pubertad : Análisis de las creencias actuales mas frecuentes

    OpenAIRE

    Mirco, Gustavo Ariel

    2013-01-01

    El presente trabajo forma parte de la especialización en fisiología del ejercicio de la Universidad Nacional de La Plata, Argentina. En este estudio se pudo comprobar la existencia de diversas creencias en cuanto a las prácticas de entrenamientos físico-deportivos en edades puberales. En primer lugar se seleccionaron algunas de las creencias consideradas mas relevantes en cuanto al impacto que pudieran ocasionar en los jóvenes practicantes. Posteriormente se confecciono un instrumento de reco...

  20. Pacientu ar mugurkaula diska trūci aprūpes problēmas pēcoperācijas periodā intensīvās terapijas nodalā

    OpenAIRE

    Šeške, Inga

    2015-01-01

    Bakalaura darba tēma - Pacientu ar mugurkaula diska trūci aprūpes problēmas pēcoperācijas periodā ITN. Tēmas aktualitāti nosaka pacientu pieaugums un problēmas, kas saistītas ar diagnozi - mugurkaula diska trūce. Darba mērķis ir noskaidrot aprūpes problēmas pacientiem ar mugurkaula diska trūci pēcoperācijas periodā ITN. Pētniecības uzdevumi ir savākt un analizēt literatūru par mugurkaula diska trūci un pacientu pēcoperācijas aprūpi, analizēt literatūru un Mairas Leivanes māszinības ...

  1. Pengaruh Harga, Kualitas Produk, Dan Citra Merek Terhadap Keputusan Pembelian Kecap Manis Merek Bango (Studi Kasus Pada Ibu Rumah Tangga Di Komplek Villa Mutiara Johor Ii Dan Taman Johor Mas)

    OpenAIRE

    Nurlisa

    2013-01-01

    This research aims to determine the effects of pricing, product quality and brand image have a significant and positive impact on purchasing decision Bango soy sauce brands on housewife in Komplek Villa Mutiara Johor II and Taman Johor Mas. The population in this research was all the housewife in the Komplek Villa Mutiara Johor II and Taman Johor Mas. Data analyzing method is by using descriptive analyzing method and multiple linear regression. Kind of this research is causal comparative. Thi...

  2. The Structure of the Fantômas Novel Series by Pierre Souvestre and Marcel Allain and the Problem of Seriality in Popular Literature

    Directory of Open Access Journals (Sweden)

    Kirill A. Chekalov

    2017-12-01

    Full Text Available The essay examines the structure of a 32-volume series of Fantômas novels created by Pierre Souvestre and Marcel Allain; it traces the origins and development of the serial genre and generic novelties related to seriality. The latter include a relative autonomy of each story in each volume and interconnection of the volumes via the figure of the criminal “slipping away” from the hands of justice. The study compares poetological techniques of the fabula development and points out specific features of the Belle époque reality as represented through the introduction of recognizable “cultural signs,” varia- tions of everyday incidents, and newspaper chronicle of criminal events. It also analyzes the image of Fantômas and other recurrent characters of the series (such as Juve, Fan- dor, Hélène, Lady Maud Beltham, etc. The authors examine para-literary features that can be traced in many other different forms such as TV series and graphic novels. They include (1 mythologization of the main character as embodiment of Evil, or a “criminal genius”; (2 confusion of the real and the fictional, verisimilar and extraordinary, horri- ble and comic based on the variations of literary and journalistic clichés; (3 repetition of plot patterns, (4 attempts to guess and to meet reader’s expectations.

  3. ANALISIS EFEKTIVITAS PENYALURAN PINJAMAN KREDIT KOPERASI OBOR MAS TERHADAP TINGKAT PENDAPATAN USAHA KECIL DAN MENENGAH DI KECAMATAN TALIBURA KABUPATEN SIKKA PROPINSI NUSA TENGGARA TIMUR

    Directory of Open Access Journals (Sweden)

    Marianus Yanto

    2017-06-01

    The aim of research to determine the effectiveness of Cooperative Credit lending income level Torch Mas towards Small and Medium Enterprises in District Talibura Sikka regency, East Nusa Tenggara province. calculation in 2010 lending loans to small and Medium Enterprises in the district Talibura included in the criteria is quite effective, and in 2011 the lending of credit to small and medium enterprises in the District Talibura increased by including in the criteria of highly effective, whereas in 2012 the distribution loans to Small and Medium Enterprises in District Talibura but has decreased but is still part of the criteria is quite effective, in 2013 the lending of credit to small and medium enterprises in the District Talibura increase included in the criteria effectively, and in 2015 the lending of credit to businesses small and Medium Enterprises has decreased but is still part of the effective criteria.Based on the results of the calculation of the income level of Small and Medium Enterprises in District Talibura in 2015, shows the distribution of cooperative credit loans against income level Torch Mas Small and Medium Enterprises in District Talibura Rp 242 million

  4. Os desastres podem até cair dos céus... Mas a culpa não é de Deus

    Directory of Open Access Journals (Sweden)

    Josué Petrônio Quirino de Oliveira

    2014-12-01

    Full Text Available O propósito desta pesquisa é apresentar uma reflexão sobre o descaso em que a politica de enfrentamento aos desastres naturais vem sendo abordada no Brasil nos últimos 100 anos.  Com uma população cada vez mais urbana as cidades passam a ser o centro não só do poder econômico e político, mas também dos mais diversos eventos decorrentes das mudanças climáticas. Uma série de problemas agrava essa urbanização vulnerável e desencadeiam uma crise socioambiental determinada por fatores sociais, políticos, econômicos, tecnológicos, culturais e ecológicos que, de forma integrada, provocam consequências devastadoras. Inundações, deslizamentos, ciclones, incêndios florestais, enxurradas, estiagens, enchentes, secas e terremotos provocam impactos inesperados e pressionam ainda mais este quadro urbano complexo a uma dinâmica preocupante. O desastre não são as principais ameaças, mas a incapacidade de planejamento e enfrentamento na gestão dos desastres demostraram o descaso com a questão foi tratado no país ao longo de décadas.

  5. Personāla atlases un apmācības sistēmas pilnveidošana uzņēmumā "X"

    OpenAIRE

    Strode, Gunta

    2012-01-01

    Bakalaura darbā „Personāla atlases un apmācības sistēmas pilnveidošana uzņēmumā „X” ” tiek izskatīti un analizēti jautājumi par personāla atlases un apmācības procesu. Darbs sastāv no trim daļām. Pirmajā daļā tiek raksturoti personāla atlases mērķi un atlases organizēšanas kārtība. Otrajā daļā tiek raksturota personāla apmācības nozīme un organizēšanas nosacījumi. Trešajā daļā tiek pētīta personāla atlases un apmācības sistēmas pilnveidošana uzņēmumā „X”. Pamatojoties uz veiktajiem ...

  6. Ekotūrisma attīstīšanas potenciāls Zebrus-Īles mežu masīvā

    OpenAIRE

    Bērziņa, Anete

    2014-01-01

    Maģistra darbs „Ekotūrisma attīstīšanas potenciāls Zebrus-Īles mežu masīvā” izstrādāts ar mērķi novērtēt Zebrus-Īles mežu masīva piemērotību ekotūrisma specializācijai. Pētījuma būtība ir novērtēt, vai pētījuma teritorijai ir potenciāls attīstīt ekotūrismu, ņemot vērā tās ekotūrisma resursus un vietējo iedzīvotāju attieksmi. Galvenie rezultāti norāda uz vides gida lielo nozīmi ekotūrisma organizēšanā un nepieciešamajām zināšanām par vietu un prasmi to nodot citiem. Kopumā iedzīvotāji atbalsta...

  7. 1H-detected MAS solid-state NMR experiments enable the simultaneous mapping of rigid and dynamic domains of membrane proteins

    Science.gov (United States)

    Gopinath, T.; Nelson, Sarah E. D.; Veglia, Gianluigi

    2017-12-01

    Magic angle spinning (MAS) solid-state NMR (ssNMR) spectroscopy is emerging as a unique method for the atomic resolution structure determination of native membrane proteins in lipid bilayers. Although 13C-detected ssNMR experiments continue to play a major role, recent technological developments have made it possible to carry out 1H-detected experiments, boosting both sensitivity and resolution. Here, we describe a new set of 1H-detected hybrid pulse sequences that combine through-bond and through-space correlation elements into single experiments, enabling the simultaneous detection of rigid and dynamic domains of membrane proteins. As proof-of-principle, we applied these new pulse sequences to the membrane protein phospholamban (PLN) reconstituted in lipid bilayers under moderate MAS conditions. The cross-polarization (CP) based elements enabled the detection of the relatively immobile residues of PLN in the transmembrane domain using through-space correlations; whereas the most dynamic region, which is in equilibrium between folded and unfolded states, was mapped by through-bond INEPT-based elements. These new 1H-detected experiments will enable one to detect not only the most populated (ground) states of biomacromolecules, but also sparsely populated high-energy (excited) states for a complete characterization of protein free energy landscapes.

  8. "KinLeaves" reklāmas aktivitātes sociālajā tīklā “Facebook” 2016. gadā

    OpenAIRE

    Mandrika, Dana

    2017-01-01

    Bakalaura darba mērķis ir izpētīt, kādas reklāmas aktivitātes uzņēmums ir veicis un noskaidrot, vai sociālajā tīklā “Facebook” ar reklāmas aktivitātēm ir iespējams sasniegt mērķauditoriju. Darbs sastāv no trīs daļām – teorētiskās, metodoloģiskās un empīriskās. Teorētisko daļu veido nodaļas par reklāmu, sociālo tīklu vietnēm, sociālo tīklu „Facebook” un reklāmu sociālo tīklu vietnēs. Metodoloģiskajā daļā apskatītas pētījumā izmantotās metodes - kontentanalīze, intervija, anketēšana. Empīrisk...

  9. Possible mechanism of the cardio-renal protective effects of AVE-0991, a non-peptide Mas-receptor agonist, in diabetic rats.

    Science.gov (United States)

    Singh, Kulwinder; Sharma, Kuldeepak; Singh, Manjeet; Sharma, P L

    2012-09-01

    This study was designed to investigate the cardio-renal protective effect of AVE-0991, a non-peptide Mas-receptor agonist, and A-779, a Mas-receptor antagonist, in diabetic rats. Wistar rats treated with streptozotocin (50 mg/kg, i.p., once), developed diabetes mellitus after 1 week. After 8 weeks, myocardial functions were assessed by measuring left ventricular developed pressure (LVDP), rate of left ventricular pressure development (dp/dt (max)), rate of left ventricular pressure decay (dp/dt (min)) and left ventricular end diastolic pressure (LVEDP) on an isolated Langendorff's heart preparation. Further, mean arterial blood pressure (MABP) was measured by using the tail-cuff method. Assessment of renal functions and lipid profile was carried out using a spectrophotometer. The administration of streptozotocin to rats produced persistent hyperglycaemia, dyslipidaemia and hypertension which consequently produced cardiac and renal dysfunction in 8 weeks. AVE0991 treatment produced cardio-renal protective effects, as evidenced by a significant increase in LVDP, dp/dt (max), dp/dt (min) and a significant decrease in LVEDP, BUN, and protein urea. Further, AVE-0991 treatment for the first time has been shown to reduce dyslipidaemia and produced antihyperglycaemic activity in streptozotocin-treated rats. However, MABP and creatinine clearance remained unaffected with AVE-0991 treatment. AVE-0991 produced cardio-renal protection possibly by improving glucose and lipid metabolism in diabetic rats, independent of its blood pressure lowering action.

  10. Um ambiente multiagent system (MAS distribuído aplicado à gestão integrada da operação portuária

    Directory of Open Access Journals (Sweden)

    Rodrigo de Alvarenga Rosa

    2016-09-01

    Full Text Available Tendo em vista o aumento do transporte marítimo no mundo e a consequente demanda por operações nos portos, os operadores buscam formas de minimizar o tempo de permanência dos navios no porto. Para atracar um navio, os portos necessitam ter disponíveis diversos recursos. Assim, planejar a designação de recursos eficientemente para não atrasar a atracação dos navios é vital para os portos. Esta designação é dinâmica, pois atrasos e antecipações na chegada dos navios ocorrem por diversos fatores demandando assim que ela seja atualizada constantemente. Este artigo propõe um Multiagent System (MAS para resolução da designação de recursos de forma distribuída e em tempo real, visando reduzir o tempo de espera para atracação dos navios. Testes foram realizados em 27 cenários e os resultados mostraram que o MAS resolveu instâncias de teste de grande porte e nos cenários mais próximos do real, ele resolveu em um tempo pequeno e com soluções estáveis.

  11. 13C and 15N CP/MAS, 1H-15N SCT CP/MAS and FTIR spectroscopy as tools for qualitative detection of the presence of zwitterionic and non-ionic forms of ansa-macrolide 3-formylrifamycin SV and its derivatives in solid state.

    Science.gov (United States)

    Przybylski, Piotr; Pyta, Krystian; Klich, Katarzyna; Schilf, Wojciech; Kamieński, Bohdan

    2014-01-01

    (13)C, (15)N CP/MAS, including (1)H-(13)C and (1)H-(15)N short contact time CP/MAS experiments, and FTIR methods were applied for detailed structural characterization of ansa-macrolides as 3-formylrifamycin SV (1) and its derivatives (2-6) in crystal and in powder forms. Although HPLC chromatograms for 2/CH3 OH and 2/CH3 CCl3 were the same for rifampicin crystals dissolved in respective solvents, the UV-vis data recorded for them were different in 300-375 nm region. Detailed solid state (13)C and (15)N CP/MAS NMR and FTIR studies revealed that rifampicin (2), in contrast to 3-formylrifamycin SV (1) and its amino derivatives (3-6), can occur in pure non-ionic or zwitterionic forms in crystal and in pure these forms or a mixture of them in a powder. Multinuclear CP/MAS and FTIR studies demonstrated also that 3-6 derivatives were present exclusively in pure zwitterionic forms, both in powder and in crystal. On the basis of the solid state NMR and FTIR studies, two conformers of 3-formylrifamycin SV were detected in powder form due to the different orientations of carbonyl group of amide moiety. The PM6 molecular modeling at the semi-empirical level of theory, allowed visualization the most energetically favorable non-ionic and zwitterionic forms of 1-6 antibiotics, strongly stabilized via intramolecular H-bonds. FTIR studies indicated that the originally adopted forms of these type antibiotics in crystal or in powder are stable in standard laboratory conditions in time. The results presented point to the fact that because of a possible presence of two forms of rifampicin (compound 2), quantification of the content of this antibiotic in relevant pharmaceuticals needs caution. Copyright © 2013 John Wiley & Sons, Ltd.

  12. APLIKASI KUANTIFIKASI KOI HERPESVIRUS : REAL TIME – QUANTITATIVE POLYMERASE CHAIN REACTION (RT-Q PCR MENGGUNAKAN SYBR GREEN PADA IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Isti Koesharyani

    2017-08-01

    Full Text Available Koi Herpes Virus (KHV di Indonesia sejak tahun 2002 merupakan penyakit mematikan yang menyerang ikan koi Cyprinus carpio koi dan ikan mas Cyprinus carpio carpio, dan sampai saat ini, infeksi KHV dilaporkan sudah menyebar hampir di seluruh dunia. Untuk mengetahui adanya infeksi KHV perlu cara diagnosa yang sangat akurat/sensitif, sehingga keberadaan KHV dapat diketahui secara pasti dengan tingkat sensitivitas yang lebih baik pada ikan budidaya. Tujuan dari penelitian ini adalah untuk mengaplikasikan teknik deteksi dengan real time quantitative polymerase chain reaction (RT- qPCR/qPCR guna mengetahui adanya infeksi KHV secara kuantitatif pada ikan mas dengan mengetahui kandungan virus (viral load. Sebanyak masing-masing 3 ekor sampel diperoleh dari sentra budidaya ikan mas di Cirata-Jawa Barat, Maninjau-Sumatera Barat, dan Banjarmasin-Kalimantan Selatan. Sampel-sampel tersebut selanjutnya dianalisa keberadaan KHV-nya dengan RT-qPCR menggunakan SYBR Green. Hasil pengujian menunjukkan bahwa jumlah tertinggi (viral load diperoleh dari ikan mas asal Cirata-3 dengan nilai Threshold Cycle (Ct. 18,24 atau setara dengan 3,4 x 107 kopi, dan terendah dari ikan mas asal Banjarmasin-3 dengan nilai Ct. 33,39 atau 1,8 x 102 kopi. Dua standar yang digunakan dalam pengujian ini berupa plasmid dengan jumlah kopi 2 x 104 (Ct 27,24 dan 2 x 103 (Ct 30,24 dan kontrol atau Non Template Control (NTC adalah 3,1 x 10 atau dengan nilai Ct 35,65. Uji aplikasi deteksi KHV dengan metode RT-qPCR ini memberikan hasil yang lebih sensitif, di mana sampel yang tidak terdeteksi dengan metode PCR konvensional dapat dideteksi dan dihitung jumlah kopi DNA (DNA copy. Since 2002, Koi herpesvirus (KHV in Indonesian has been a malignant diseases, now recognized as a worldwide cause of mortality among populations of koi Cyprinus carpio koi and common carp Cyprinus carpio carpio. To determine the presence of infection is required the KHV diagnosis method with highly accurate and sensitive

  13. 13C CP MAS NMR and GIAO-CHF/DFT calculations of flavonoids: Morin, kaempferol, tricin, genistein, formononetin and 3,7-dihydroxyflavone

    Science.gov (United States)

    Zielińska, Agnieszka; Paradowska, Katarzyna; Jakowski, Jacek; Wawer, Iwona

    2008-02-01

    13C CP MAS NMR spectra of the flavonoids: morin, kaempferol, 3,7-dihydroxyflavone, tricin and isoflavones: genistein and formononetin were recorded to characterize solid-state conformations. Intramolecular hydrogen bonds forming five-, six- and seven-membered rings are present in the two morin molecules in the crystals - their 13C resonances have been assigned with the aid of the calculated shielding constants. Linear relationships between the calculated shielding constants σDFT (ppm) and chemical shifts ( δCPMAS, ppm) were obtained for all studied compounds. Higher correlation coefficients suggest that the conformation with "clockwise" orientation of both OH groups is more probable in the solid 3,7-dihydroxyflavone, whereas in the solid formononetin the OH and OCH 3 substituents are directed "anticlockwise". The barrier to the rotation of phenyl ring B decreases in the order: morin (2'-OH, 3-OH) > kaempferol (3-OH) > tricin.

  14. Sou eu, mas não sou eu: as interações de mulheres mexicanas com o álcool

    OpenAIRE

    Leticia Cortaza Ramírez

    2007-01-01

    O consumo de álcool na mulher é uma problemática cada dia maior devido ao aumento nos padrões de consumo e na idade precoce em que se da o início do consumo de bebidas alcoólicas. O processo de adição é complexo e afeta a mulheres de todas as classes sociais, estas mulheres vistas em uma perspectiva externa não parecem ter muitas coisas em comum, mas compartilham o consumo de álcool de maneira impulsiva. Daí surge a finalidade deste estudo que foi compreender em que momento o álcool começou a...

  15. Characterization of interphases appearing on LiNi{sub 0.5}Mn{sub 0.5}O{sub 2} using {sup 7}Li MAS NMR

    Energy Technology Data Exchange (ETDEWEB)

    Dupre, Nicolas; Guyomard, Dominique [Institut des Materiaux Jean Rouxel, 2 rue de la Houssiniere, BP 32229, F-44322 Nantes Cedex 3 (France); Martin, Jean-Frederic [Institut des Materiaux Jean Rouxel, 2 rue de la Houssiniere, BP 32229, F-44322 Nantes Cedex 3 (France); Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori, Yokohama 226-8502 (Japan); Yamada, Atsuo; Kanno, Ryoji [Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori, Yokohama 226-8502 (Japan)

    2009-04-01

    {sup 7}Li MAS NMR, usually a bulk characterization technique, is used here to analyze the positive electrode/electrolyte interphase. The sharpening of the NMR spectra line shape as the amount of surface species increases shows that the observed signal is clearly the sum of signals due to the distribution of lithium ions in the interphase in terms of distance from the bulk of electrode active material. This technique is then used to compare characteristics of the interphase coming from the contact with LiPF{sub 6}-based electrolyte in the case of storage or electrochemical cycling. A clear influence of the change of potential on the interphase configuration and in particular on its intimacy with the bulk of active material is deduced from the change in NMR spectra lineshape. This information is hardly obtained by other characterization technique, making NMR a powerful tool for the study of interphases and passivation layers in lithium batteries materials. (author)

  16. Identification of Li-Ion Battery SEI Compounds through (7)Li and (13)C Solid-State MAS NMR Spectroscopy and MALDI-TOF Mass Spectrometry.

    Science.gov (United States)

    Huff, Laura A; Tavassol, Hadi; Esbenshade, Jennifer L; Xing, Wenting; Chiang, Yet-Ming; Gewirth, Andrew A

    2016-01-13

    Solid-state (7)Li and (13)C MAS NMR spectra of cycled graphitic Li-ion anodes demonstrate SEI compound formation upon lithiation that is followed by changes in the SEI upon delithiation. Solid-state (13)C DPMAS NMR shows changes in peaks associated with organic solvent compounds (ethylene carbonate and dimethyl carbonate, EC/DMC) upon electrochemical cycling due to the formation of and subsequent changes in the SEI compounds. Solid-state (13)C NMR spin-lattice (T1) relaxation time measurements of lithiated Li-ion anodes and reference poly(ethylene oxide) (PEO) powders, along with MALDI-TOF mass spectrometry results, indicate that large-molecular-weight polymers are formed in the SEI layers of the discharged anodes. MALDI-TOF MS and NMR spectroscopy results additionally indicate that delithiated anodes exhibit a larger number of SEI products than is found in lithiated anodes.

  17. Deafness memories in Antonio Lobo Antunes’ chronicles “O surdo” (1998 and “Não foi com certeza assim mas faz de conta” (2002

    Directory of Open Access Journals (Sweden)

    Alessandra Gomes Silva

    2017-06-01

    Full Text Available This work intends to analyze some images and meanings attributed to deafness in two chronicles of Portuguese writer António Lobo Antunes: “Não foi com certeza assim mas faz de conta” (2002 and “O surdo” (1998. We are also interested in the type of creation of these texts, drawing a parallel with the kind of reflection developed in some writings of Walter Benjamin, basically in “One-way street” and “Berlin childhood”. In both authors, the fictional production is linked to the issue of memory, taking as its starting point the contact with a seemingly simple everyday object. Finally, we emphasize the discussion of the normalization of bodies, based on the issue of not hearing and how it is socially perceived.---DOI: http://dx.doi.org/10.22409/abriluff.2017n18a369

  18. Fate of [15N]glycine in peat as determined by 13C and 15N CP-MAS NMR spectroscopy

    International Nuclear Information System (INIS)

    Benzing-Purdie, L.M.; Cheshire, M.V.; Williams, B.L.; Sparling, G.P.; Ratcliffe, C.I.; Ripmeester, J.A.

    1986-01-01

    Peat samples, nonsterile, sterilized by γ irradiation or autoclaving, were incubated with [ 15 N]glycine for a period of 6 months. The 13 C NMR data showed the established trend of increased humification with decreasing particle size and that autoclaving had significantly disturbed the humification-particle size distribution. The 15 N CP-MAS NMR spectra showed the presence of [ 15 N]glycine in all fractions after incubation. 15 NH 4 + , a result of either biological or chemical deamination, was one of the main products in the nonsterile peat series. The 15 N spectra also showed resonances corresponding to amine, secondary amide, and pyrrole-type nitrogen and the presence of glycine derivatives and melanoidins. The results presented give the first spectroscopic evidence of the possible involvement of the Maillard reaction in the humification process

  19. The influence of angiotensin-(1-7) Mas receptor agonist (AVE 0991) on mitochondrial proteome in kidneys of apoE knockout mice.

    Science.gov (United States)

    Suski, Maciej; Olszanecki, Rafał; Stachowicz, Aneta; Madej, Józef; Bujak-Giżycka, Beata; Okoń, Krzysztof; Korbut, Ryszard

    2013-12-01

    Excessive action of angiotensin II on mitochondria has been shown to play an important role in mitochondrial dysfunction, a common feature of atherogenesis and kidney injury. Angiotensin-(1-7)/Mas receptor axis constitutes a countermeasure to the detrimental effects of angiotensin II on AT1 receptors. The aim of the study was to assess the effects of angiotensin-(1-7) peptidomimetic AVE0991 on the kidney mitochondrial proteome in widely used animal model of atherosclerosis (apoE(-/-) mice). Proteins changed in apoE(-/-) mice belonged to the groups of antioxidant enzymes, apoptosis regulators, inflammatory factors and metabolic enzymes. Importantly, AVE0991 partially reversed atherosclerosis-related changes in apoE(-/-) mice. © 2013.

  20. Satura pārvaldības sistēmas Joomla! paplašinājumu izstrāde

    OpenAIRE

    Zariņa, Evita

    2012-01-01

    Kvalifikācijas darbā tika izstrādāti Joomla paplašinājumi. Viens no tiem bija notikumu kalendārs, kas tika veidots SIA „Datorikas institūts DIVI” un AS „Latvijas valsts meži” sadarbības līguma „Par satura pārvaldības sistēmas un WEB portāla izstrādi, izvietošanu un 3 gadu uzturēšanu” ietvaros. Tā izveidošanā tika izmantots atklātā pirmkoda paplašinājums „PHP Quick Calendar E”, kura pirmkodā tika veiktas izmaiņas, balstoties uz GNU Vispārējo publisko licenci. Izstrādātais paplašinājums ļauj ad...

  1. Transitions in Al Coordination during Gibbsite Crystallization Using High-Field 27 Al and 23 Na MAS NMR Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jian Zhi [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Zhang, Xin [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Jaegers, Nicholas R. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Washington State University, Pullman, Washington 99164, United States; Wan, Chuan [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Graham, Trent R. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Washington State University, Pullman, Washington 99164, United States; Hu, Mary [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Pearce, Carolyn I. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Felmy, Andrew R. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Washington State University, Pullman, Washington 99164, United States; Clark, Sue B. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States; Washington State University, Pullman, Washington 99164, United States; Rosso, Kevin M. [Pacific Northwest National Laboratory, Richland, Washington 99354, United States

    2017-11-30

    Mechanisms of nucleation and growth of Al hydroxides such as gibbsite from aqueous solution, particularly in highly alkaline conditions, remain poorly understood. In this work, quantitative 27Al and 22Na MAS NMR experiments were conducted on solid samples extracted from the crystallization of gibbsite from an amorphous aluminum hydroxide gel precursor. The use of high magnetic field and fast sample spinning allowed transitional tetrahedral (AlT) and pentahedral (AlP) aluminum species to be observed along with the octahedral aluminum (AlO) that dominates the gibbsite product. Low-coordinated Al species could be detected at concentrations as low as 0.1% of the total Al sites. It is established that (a) AlT and AlP coexist on the surface of growing gibbsites even with a combined percentage over the total Al sites of less than 1%; (b) Different synthesis methods generate gibbsite with varying amounts of low-coordinated Al; (c) the amorphous gel precursor contains a significant amount of low-coordinated Al sites with AO: AlP: AlT ratios of approximately 4:2:1; (d) upon hydration, the external, low-coordinated Al sites become six-fold coordinated by interacting with the oxygen in H2O and the 27Al MAS NMR peak position shifts to that for the AlO sites; (e) gibbsite with increased long range order is synthesized over longer times by gradually incorporating residual AlP and AlT sites into octahedrally-coordinated AlO sites; (f) trace Na is predominantly a surface species on gibbsite particles. These findings provide a basis for understanding the gibbsite crystallization mechanism, along with a general means of characterizing gibbsite surface properties that are of equal importance for understanding related processes such as dissolution behavior.

  2. Identifikasi Waste pada Produksi Kayu Lapis dengan Pendekatan Lean Manufacturing untuk Meningkatkan Kualitas Proses Produksi (Studi Kasus : PT Sumber Mas Indah Plywood

    Directory of Open Access Journals (Sweden)

    Miftahus Shomad

    2017-03-01

    Full Text Available This research aimed at identifying the wastes of plywood production in PT Sumber MasIndah Plywood. Results were then utilized to determine methods in reducing wastes. Theidentification of waste was carried out using lean manufacturing approach. The data werecollected from manufacturer records, study to determine processing time, as well as interviewand quisioners which were distributed to workers in each department. Big picture mapping andvalue stream mapping tools (VALSAT were then utilized to process the data. Results ofanalyses using big picture mapping showed that total production lead time was 438,8 minutes,with 235,97 minutes of them were value added activities; and 27 days of total information leadtime. Workshop waste analyses resulted in the highest waste generated during plywoodproduction process. Those were 133 waiting time (delay, 113 defect and 78 excessivetransportation. Further analyses using VALSAT showed three methods to identify the data inmore detail, namely process activity mapping (PAM, supply chain response matrix (SCRMand quality filter mapping (QFM. Results from PAM method revealed 125 activities duringproduction, consist 62 value added activities, 33 necessary but non value added activities and 30non value added activities. While results from SCRM showed the average 22,63 days of totalorder fulfillment process comprised of 4,13 days of total physical stock and 18,5 days of totallead time. QFM result showed ratio of scrap defect reject 0,4% and ratio of scrap defect UTY3,46%. In general waste in plywood production at PT Sumber Mas Indah Plywood wasgenerated from worker, material, machinery, methods and environment. One of the ways toimprove it is by applying pull system (Kanban

  3. Atomic structure and dehydration mechanism of amorphous silica: Insights from 29Si and 1H solid-state MAS NMR study of SiO2 nanoparticles

    Science.gov (United States)

    Kim, Hyun Na; Lee, Sung Keun

    2013-11-01

    Detailed knowledge of the atomic structure of hydrous species on surface of amorphous silica and the effect of temperature and particle size on their atomic configurations are essential to understand the nature of fluids-amorphous silicates interactions and the dehydration processes in the amorphous oxides. Here, we report the 29Si, 1H MAS, and 1H-29Si heteronuclear correlation (HetCor) NMR spectra of 7 nm and 14 nm amorphous silica nanoparticles—a model system for natural amorphous silica—where previously unknown details of changes in their atomic structures with varying dehydration temperature and particle size are revealed. Diverse hydroxyl groups with varying atomic configurations and molecular water apparently show distinct dehydration trends. The dehydration (i.e., removal of water) of amorphous silica nanoparticles mostly results in the increase of isolated silanol by removing water molecules from hydrogen-bonded silanols associated water molecules. With further increase in dehydration temperature, the intensity of isolated silanol peak decreases above ˜873 K, suggesting that the condensation of isolated silanol may occur mainly above ˜873 K. The entire dehydration (and dehydroxylation) process completes at ˜1473 K. Both the water (i.e., physisorbed water and hydrogen-bonded water) and hydrogen-bonded silanol species show a dramatic change in the slope of intensity variation at ˜873 K, indicating that most of silanols is hydrogen-bonded to water rather than to other silanols. The fraction of hydrogen-bonded proton species is also much smaller in 14 nm amorphous silica nanoparticles than in 7 nm amorphous silica nanoparticles mainly due to the presences of larger fractions of water and hydrogen-bonded silanol species. 29Si NMR results show that with increasing dehydration temperature, the fraction of Q4 species apparently increases at the expense of Q2 and Q3 species. The fractions of Q2 and Q3 structures in 7 nm amorphous silica nanoparticles are

  4. Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry.

    Science.gov (United States)

    Dinda, Biswanath; Kyriakopoulos, Anthony M; Dinda, Subhajit; Zoumpourlis, Vassilis; Thomaidis, Nikolaos S; Velegraki, Aristea; Markopoulos, Charlambos; Dinda, Manikarna

    2016-12-04

    Cornus mas L. (cornelian cherry) fruits have been used for centuries as traditional cuisine and folk medicine in various countries of Europe and Asia. In folk medicines, the fruits and other parts of the plant have been used for prevention and treatment of a wide range of diseases such as diabetes, diarrhea, gastrointestinal disorders, fevers, rheumatic pain, skin and urinary tract infections, kidney and liver diseases, sunstroke, among others. This review provides a systematic and constructive overview of ethnomedicinal uses, chemical constituents and pharmacological activities of this plant as well as future research need for its commercial utilization as nutraceutical food supplement and medicine. This review is based on available literature on ethnomedicinal uses, phytochemical, pharmacological, toxicity and clinical studies on Cornus mas L. (cornelian cherry) fruits and other organs that was collected from electronic (SciFinder, PubMed, Science Direct and ACS among others) and library searches of books and journals. Versatile ethnomedicinal uses of the plant in different European and Asian countries have been reported. Phytochemical investigations on different parts of this plant have resulted in the identification of 101 compounds, among which anthocyanins, flavonoids and iridoids are the predominant groups. The crude extracts of fruits and other parts of the plant and their pure isolates exhibit a broad spectrum of pharmacological activities such as anti-microbial, anti-diabetic, anti-atherosclerotic, cyto-, hepato-, neuro- and renalprotective, antiplatelet and antiglaucomic activities. Anthocyanins, flavonoids, iridoids and vitamin C are the major bioactive constituents of the fruits. Fruits are non-toxic and safe food on acute toxicity studies in rat and human models. Clinical trials in diabetic type2 and hyperlipidemic patients showed significant trends of amelioration in sugar level, insulin secretion in diabetic patients and amelioration of lipid

  5. De masonería, control y otras lealtades fraternales: el rescate de Porfirio Díaz por un hermano masón

    Directory of Open Access Journals (Sweden)

    Guillermo de los Reyes Heredia

    2015-01-01

    Full Text Available En este artículo se explora el papel que jugó Porfirio Díaz dentro de la masonería y su relación con dichainstitución. Se analiza una de las historias que comprueban que Díaz logró ciertos beneficios gracias a suafiliación masónica desde antes que fuera presidente de México. Esta historia narra la manera en que Díazlogró entrar de contrabando a México con la ayuda de un hermano masón en 1876, después de su breve exilioen Nuevo Orleans a bordo del buque de vapor, “City of Havana”. En un principio se pensaba que ésta erasimplemente una leyenda más del folklore que envuelve a la masonería. Sin embargo, dos testimonios, ambosde masones que iban en el mismo barco ratifican la historia que incluso el mismo historiador de la masoneríanorteamericana, William Deslow, catalogaba como un incidente, “no verificado.”Asimismo, se describe cómo Díaz promovió la unificación de las logias del rito escocés en unainstitución que se llamó La Gran Dieta Simbólica. La razón principal por la cual Díaz promovió talunificación, como se afirma en este artículo, fue para llevar a cabo su plan de pacificación nacional. Díazsabía que tenía que obtener el control de la masonería para evitar que ésta le causara problemas para lograr elorden y progreso que caracterizó a su gobierno. Por tal motivo, el dictador siempre vigiló que ni la masonería,ni cualquier otra institución que hubiera podido tener cierta influencia en la sociedad estuvieran fuera de sucontrol.

  6. In situ (1)H and (13)C MAS NMR kinetic study of the mechanism of H/D exchange for propane on zeolite H-ZSM-5.

    Science.gov (United States)

    Arzumanov, Sergei S; Reshetnikov, Sergei I; Stepanov, Alexander G; Parmon, Valentin N; Freude, Dieter

    2005-10-27

    The kinetics of hydrogen (H/D) exchange between Brønsted acid sites of zeolite H-ZSM-5 and variously deuterated propanes (propane-d(8), propane-1,1,1,3,3,3-d(6), propane-2,2-d(2)) have been monitored in situ by (1)H MAS NMR spectroscopy within the temperature range of 503-556 K. The contribution of intramolecular hydrogen transfer to the H/D exchange in the adsorbed propane was estimated by monitoring the kinetics of (13)C-labeled carbon scrambling in propane-2-(13)C in situ with (13)C MAS NMR at 543-573 K. Possible mechanisms of the exchange have been verified on the basis of the analysis of the variation of protium concentration in both the methyl and the methylene groups of propane in dependence of the reaction time. The main route of the exchange consists of a direct exchange of the acidic OH groups of the zeolite with either the methyl groups or the methylene group presumably with a pentacoordinated carbonium ion intermediate. The assumption that the intramolecular H scrambling between the methyl groups and the methylene group of propane via carbenium-ion-type intermediates is the fastest process among the other possible routes does not account for the experimental kinetics of H/D exchange for propanes with different initial contents and locations of deuterium in a propane molecule. The rate constant (k(3)) for intramolecular H/D exchange between the methyl and the methylene groups is 4-5 times lower compared to those of the direct exchange of both the methyl (k(1)) and the methylene (k(2)) groups with Brønsted acid sites of the zeolite, the k(1) being ca. 1.5 times higher than k(2). At lower temperature (473 K), the exchange is slower, and the expected difference between k(1) and k(2) is more essential, k(1) = 3k(2). This accounts for earlier observed regioselectivity of the exchange for propane on H-ZSM-5 at 473 K. Faster direct exchange with the methyl groups compared to that with the methylene groups was attributed to a possible, more spatial

  7. Mas Roig Mini-Grid

    DEFF Research Database (Denmark)

    Salas, Pep; Guerrero, Josep M.

    2014-01-01

    are classified in four different types according to priority and are controlled by intelligent sockets interconnected in a mesh network. Each socket measures the main electric parameters, communicates to the local computer bidirectionality by using ZigBee communications, and is able to switch on/off the loads...

  8. Saber, Sentir, Pagar, mas Como?

    OpenAIRE

    Macedo, Duarte Gaspar de Lacerda

    2016-01-01

    Um dos objectivos deste estudo passa por perceber de que forma o grau de aversão à dívida influencia a tomada de decisão sobre qual o método de pagamento – pré-pagamento ou póspagamento - escolhido no momento da compra pelo consumidor. Concluir se aqueles consumidores que têm um menor grau de Literacia Financeira tendem a optar por póspagamento é outro dos objectivos deste estudo. Numa outra fase deste estudo, concluir se a diferença entre Produto e Serviço influencia a tomada ...

  9. High Tech M&As

    DEFF Research Database (Denmark)

    Toppenberg, Gustav

    2013-01-01

    Technology driven industries have seen fast moving technology changes, higher complexity and reduced product life cycles. These emerging trends present challenges for companies in industries where technology is at the forefront. The extant research deals with ‘low-tech’ industries and majority of......&A teams in this sector. The phenomenon is studied from multiple perspectives: integration team, acquiring group and the company being acquired....... of findings are not applicable to the high-tech industry; in fact this industry has many additional challenges. In this study, we aim to explore the process of M&A in the high-tech industry by drawing on extant literature and empirical field work. The paper outlines a research project in progress which...

  10. El MAS-IPSP como proyecto político-identitario en Bolivia. Reflexiones sobre una experiencia estética y política

    Directory of Open Access Journals (Sweden)

    María Virginia Quiroga

    2014-12-01

    Full Text Available Este artículo parte del análisis del ascendente proceso de movilización social boliviano, hacia fines del siglo XX y comienzos del XXI. El intenso ciclo de acción colectiva resultó, en parte, canalizado a través de la propuesta del Movimiento Al Socialismo-Instrumento Político por la Soberanía de los Pueblos (MAS-IPSP que triunfó consecutivamente en las elecciones presidenciales de diciembre de 2005 y de diciembre de 2009. A lo largo del texto argumentamos que la experiencia boliviana reciente trae a escena implicancias estéticas y políticas. El instrumento político tomó distancia de la noción de partido político tradicional e intentó preservar parte de la mística movimentista y militante, como también ciertos legados y prácticas propias del mundo indígena. A su vez, la victoria electoral de una alternativa proveniente de las organizaciones campesinas e indígenas, representó la esperanza de inclusión y dignidad para sectores sociales históricamente excluidos y políticamente invisibilizados.

  11. Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats.

    Science.gov (United States)

    Asgary, Sedigheh; Rafieian-Kopaei, Mahmoud; Shamsi, Fatemeh; Najafi, Somayeh; Sahebkar, Amirhossein

    2014-06-01

    Anthocyanins are phytochemicals with a multitude of pharmacological actions including anti-diabetic and anti-hyperlipidemic effects. This study was undertaken to evaluate the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L., CM) fruits - that are rich in anthocyanins and known to have medicinal properties- in alloxan-induced diabetic rats. Twenty-eight adult male rats were randomly assigned to four groups of seven animals each: non-diabetic control, diabetic control, glibenclamide-treated (0.6 mg/kg/day; 4 weeks) and CM fruit-treated (2 g/day; 4 weeks) group. Diabetes was induced by a single injection of alloxan (120 mg/kg). Fasting serum levels of glucose, total cholesterol (TC), low- (LDL-C) and high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), aspartate (AST) and alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were measured at the end of study period. Diabetic rats had significantly elevated levels of serum glucose, LDL-C, TG, AST, ALP and ALT and decreased levels of HDL-C compared to the non-diabetic group (pdiabetic control group (pfruits effectively prevents the development of diabetes mellitus, dyslipidemia and hepatic inflammation in alloxan-induced diabetes.

  12. Assessing the performance of windowed 1H CRAMPS methods, on biological solids, at high-field and MAS up to 35 kHz

    Science.gov (United States)

    Mafra, Luís; Coelho, Cristina; Siegel, Renée; Rocha, João

    2009-03-01

    The performance of various high-resolution 1D 1H CRAMPS pulse schemes at moderate and high static magnetic fields (400 MHz and 800 1H Larmor frequencies) and spinning rates up to 35 kHz, using state-of-the-art electronics is compared. The performance of the 1H windowed acquisition decoupling schemes, wDUMBO, wPMLG3 and wSAM3 is investigated using their effective z-rotation variants on glycine and other small biological molecules, tripeptide reduced glutathione and nucleoside uridine. 1H CRAMPS spectra, recorded with windowed 1H- 1H decoupling methods and fast MAS (35 kHz) and high-field are reported for the first time. 1H spectra exhibiting outstanding resolution and completely free from any artifact are also shown. The effect on spectra quality of the decoupling rf cycle and rotor periods ratio ( τC/τR) and the power requirements needed for each windowed 1H CRAMPS methods are discussed.

  13. A Multiplex Allele Specific Polymerase Chain Reaction (MAS-PCR) for the Detection of Factor V Leiden and Prothrombin G20210A

    Science.gov (United States)

    Bagheri, Morteza; Rad, Isa Abdi

    2011-01-01

    ABSTRACT Introduction: In order to determine the frequencies of factor V Leiden and prothrombin G20210A point mutations in the Iranian population with Azeri Turkish origin. Material and methods: 120 unrelated individuals from general population randomly selected and were examined for factor V Leiden and prothrombin G20210A mutations using a multiplex allele specific polymerase chain reaction (MAS-PCR) assay Outcomes: The frequency of prothrombin G20210A mutation was 2.08%, which means 5 chromosomes out of 240 chromosomes had prothrombin G20210A mutation. The distribution of prothrombin 20210 GG, GA, AA genotypes and prothrombin 20210A allele were 37(92.5%), 3(7.5%), 0(0%) and 3(3.75%) in males and 78(97.5%), 2(2.5%), 0(0%) and 2(1.25%) in females, respectively. Factor V Leiden was not found in our tested group (zero chromosomes out of 240 chromosomes). Analysis of the observed frequencies in the studied groups indicates that there is no statistically significant difference between females and males, regarding prothrombin G20210A mutation (p value>0.05). Conclusions: This is the first study in its own kind in this population and implies that the frequency of Factor V Leiden G1691A (R506Q, FV-Leiden) allele is extremely low but the prothrombin G20210A mutation is more frequent in the tested group. PMID:21977183

  14. Žurnāla SHAPE pārpozicionēšanas stratēģijas problēmas un risinājumi.

    OpenAIRE

    Nikodemusa, Zane

    2013-01-01

    Maģistra darba tēma ir „Žurnāla SHAPE pārpozicionēšanas stratēģijas problēmas un risinājumi”. Maģistra darba mērķis ir izpētīt žurnāla SHAPE pārpozicionēšanas stratēģiju, tās ieguvumus un zaudējumus no uzņēmuma skatu punkta, kā arī ietekmējošos faktorus un risinājumus turpmākai tirgus pozīcijas stiprināšanai. Darba gaitā autore izmanto dažādas informācijas apkopošanas un analīzes metodes. Teorētiskās daļas veidošanai darba autore izmantoja literatūras referatīvās analīzes metodi. Informāci...

  15. Do Povo e para o povo, mas nâo por ele mesmo: o sistema penal como controle/limitação da democracia

    Directory of Open Access Journals (Sweden)

    Jackson da Silva Leal

    2015-03-01

    Full Text Available O presente trabalho analisa a problemática envolvendo as manifestações que ocorreram no Brasil ao longo de todo o ano de 2013, mas de forma mais intensa no mês de junho deste ano, e os confrontos com as agencias de controle social que se produziram. Nesta linha, analisa-se na perspectiva permitida a partir da criminologia critica e de uma sociologia politica de matriz marxista, e também retomando a concepção de criminoso elucidada por Alessandro Baratta (1999. O presente trabalho é construído eminentemente com base em referencial teórico e bibliográfico. Tem-se o objetivo de contribuir com uma compreensão adensada da realidade contemporânea e aportar a contribuição da criminologia crítica latino-americana para as funções que desempenha o controle social nestes períodos de turbulência popular e confronto com o projeto de poder burguês-classista. 

  16. The combined use of quantum chemical calculations and CP/MAS NMR spectroscopy to investigate soil bound residues of labeled xenobiotics

    Science.gov (United States)

    Lewandowski, Hans; Philipp, Herbert; Meier, Robert J.; Narres, Hans-Dieter; Berns, Anne E.

    2010-05-01

    Application of solid state Nuclear Magnetic Resonance (NMR) spectroscopy to 13C- and 15N-labeled compounds is a powerful tool to study the interactions of xenobiotics with soil and its components. The type of interaction with soil components, like organic matter or the mineral phase, influences binding and release of a xenobiotic and its metabolites in soil. As such interactions to the soil matrix cause shifts in the initial positions of the NMR signals of the investigated labeled compound, NMR can be used to elucidate the binding type of bound residues. Density functional theory (DFT) calculations are excellent suited to support such NMR studies of xenobiotics. In a first step, DFT calculations were used to support the interpretation of the spectra of labeled xenobiotics, their metabolites and reaction products synthesized through reaction with model substances (representing specific functionalities of humic substances). In a second step, they allow to evaluate the influence of possible bonds on the initial chemical shift (e.g. towards higher or lower field). This can be especially helpful in the case of bonds like van-der-Waals interactions, for which it is difficult to prepare defined model substances. CP/MAS-NMR spectroscopy and DFT calculations were applied to study the interactions of several labeled xenobiotics and soil organic matter.

  17. PENGARUH BRAND IMAGE DAN BRAND TRUST TERHADAP BRAND LOYALTY TEH BOTOL SOSRO Survei Konsumen Teh Botol Sosro di Food Court ITC Cempaka Mas, Jakarta timur

    Directory of Open Access Journals (Sweden)

    Mohammad Rizan

    2012-04-01

    Full Text Available The purposes of this research are: 1 To know the description of brand image and brand trust and the influence of them towards brand loyalty of Teh Botol Sosro. 2 To test empirically the influence of brand image towards brand loyalty of Teh Botol Sosro. 3 To test empirically the influence of brand trust towards brand loyalty of Teh Botol Sosro. 4 To test empirically the influence of brand image and brand trust simultaneously towards brand loyalty of Teh Botol Sosro. The analysis implemented in this research are descriptive and causal analysis. This research is taken 100 consumers of Teh Botol Sosro at the food court of ITC Cempaka Mas while data was collected by using questionnaire and processed using SPSS 16. The result shows that partially brand image has a positive and significant impact toward brand loyalty. Then, partially brand trust also has a positive and significant impact toward brand loyalty. Simultaneously, brand image and brand trust have a positive and significant impact toward brand loyalty. The empirical findings indicate that to create and improve the brand loyalty, Teh Botol Sosro need to consider brand image and brand trust because those factors shown to affect the level of job satisfaction.

  18. PENGARUH ATRIBUT PRODUK DAN VARIETY SEEKING TERHADAP KEPUTUSAN PERPINDAHAN MEREK HANDPHONE NOKIA KE SMARTPHONE SAMSUNG (Survei pada outlet Okeshop ITC Roxy Mas, Jakarta Pusat

    Directory of Open Access Journals (Sweden)

    Setyo Ferry Wibowo

    2014-04-01

    Full Text Available The purpose of the research are: to know the description of product attributes, variety seeking, and brand switching decision of hand phone Nokia to Samsung Smartphone, test empirically the influence of product attributes toward brand switching decision of hand phone Nokia to Samsung smartphone, test empirically the influence of variety seeking toward brand switching decision of hand phone Nokia to Samsung smartphone, test empirically the influence of product attributes and variety seeking toward brand switching decision of hand phone Nokia to Samsung smartphone. This is a quantitative research, descriptive and causal design, collecting data by survey method. Population of this research is visitors of Outlet Oke shop ITC Roxy mas, Central Jakarta who use Samsung smartphone and had use hand phone Nokia before. Analysis of the research was conducted using SPSS. The results of the t test shows the product attributes and brand switching significantly influence the significance value, and variety seeking toward brand switching are also significantly influence. The results of F test simultaneously indicates product attributes and variety seeking influencing significantly to brand switching. And the result of determination analysis in this research shows the variation of variables product attributes and variety seeking could explained brand switching together. While the remaining are explained by other variables that are not included in this research model.

  19. 13C and 31P CP/MAS NMR studies of the polytopal ligand rearrangement process of tungsten tris(trimethylphospine) hexahydride in the solid state

    International Nuclear Information System (INIS)

    Heyes, S.J.; Green, M.L.H.; Dobson, C.M.

    1991-01-01

    W(PMe 3 ) 3 H 6 (1), an archetypal nine-coordinate transition-metal complex, has been studied in the crystalline state by variable-temperature 13 C and 31 P CP/MAS NMR spectroscopy. The NMR spectra are consistent with a tricapped-trigonal-prismatic geometry for the complex, with two phosphine ligands in eclipsed prismatic sites and the third capping the prismatic face opposite the other two. The two prismatic phosphines are shown to be on inequivalent sites. At temperatures above 340 K, exchange broadening shows the occurrence of ligand functionality interchange between the different phosphine environments. Analysis of these line shapes and magnetization-transfer data, in the slow limit of exchange, for the both 13 C and 31 P nuclei shows activation parameters of E a = 148.8 ± 15 kJ mol -1 and A = 6.6 x 10 23 s -1 for the ligand-functionality-interchange process. The most likely mechanism involves a double-rearrangement mechanism with polyhedral edge stretches through a monocapped-square-antiprismatic geometry to a tricapped-trigonal-prismatic intermediate in which all phosphines occupy capping positions. This allows complete scrambling of the ligand functionality, in a manner such that the spatial movement of the phosphine ligands within the crystalline frame need only be relatively small. An additional dynamic process, involving a tripod reorientation of the PMe 3 rotors, has been detected by dipolar broadening of the 13 C NMR spectra. 31 refs., 10 figs., 2 tabs

  20. (1)H HR-MAS spectroscopy for quantitative measurement of choline concentration in amniotic fluid as a marker of fetal lung maturity: inter- and intraobserver reproducibility study.

    Science.gov (United States)

    Joe, Bonnie N; Vahidi, Kiarash; Zektzer, Andrew; Chen, Mei-Hsiu; Clifton, Matthew S; Butler, Thomas; Keshari, Kayvan; Kurhanewicz, John; Coakley, Fergus; Swanson, Mark G

    2008-12-01

    To determine the intra- and interobserver reproducibility of human amniotic fluid metabolite concentration measurements (including potential markers of fetal lung maturity) detectable by MR spectroscopy. (1)H high-resolution magic angle spinning (HR-MAS) spectroscopy was performed at 11.7 T on 23 third-trimester amniotic fluid samples. Samples were analyzed quantitatively using 3-(trimethylsilyl)propionic-2,2,3,3-d(4) acid (TSP) as a reference. Four observers independently quantified eight metabolite regions (TSP, lactate doublet and quartet, alanine, citrate, creatinine, choline, and glucose) twice from anonymized, randomized spectra using a semiautomated software program. Excellent inter- and intraobserver reproducibility was found for all metabolites. Intraclass correlation as a measure of interobserver agreement for the four readers ranged from 0.654 to 0.995. A high correlation of 0.973 was seen for choline in particular, a major component of surfactant. Pearson correlation as a measure of intraobserver reproducibility ranged from 0.478 to 0.999. Quantification of choline and other metabolite concentrations in amniotic fluid by high-resolution MR spectroscopy can be performed with high inter- and intraobserver reproducibility. Demonstration of reproducible metabolite concentration measurements is a critical first step in the search for biomarkers of fetal lung maturity. (c) 2008 Wiley-Liss, Inc.

  1. Tirdzniecības sistēmas izstrādāšana starpbanku valūtas tirgū

    OpenAIRE

    Paļitovs, Aleksandrs

    2012-01-01

    Bakalaura darba tēma ir „Tirdzniecības sistēmas izstrādāšana starpbanku valūtas tirgū”. Valūtu tirgus popularitāti veicinājusi finanšu tirgus globalizācija, datorizācija un Interneta izmantošanas palielināšanās, kā arī relatīvi neliels nepieciešamais sākotnējais ieguldījums. Ļoti bieži iesācēji bez priekšzināšanām un pieredzi valūtu tirgū pazaudē savu depozītu. Forex tirdzniecība par 80% balstās uz paša treidera psiholoģiju. Lai minimizētu treideru emocionālus un psiholoģiskus faktorus, autor...

  2. Kukuļņemšanas un kukuļdošanas kvalifikācijas problēmas

    OpenAIRE

    Brauere, Jolanta

    2010-01-01

    Bakalaura darba nosaukums ir „Kukuļņemšanas un kukuļdošanas kvalifikācijas problēmas”. Darba mērķis ir izpētīt normatīvos aktus, speciālo juridisko literatūru un judikatūru, nolūkā konstatēt problēmas kukuļņemšanas un kukuļdošanas kvalifikācijā. Lai sasniegtu šo mērķi, darbā tika aplūkota kukuļņemšanas un kukuļdošanas vēsturiskā attīstība, tādējādi sniedzot nelielu ieskatu par kukuļņemšanas un kukuļdošanas juridiskā pamata vēsturiskās attīstības posmiem no 19.gadsimta līdz mūsdienām. Darb...

  3. Rīgas sociālās vides reklāmas ietekme uz auditoriju: ētikas un efektivitātes kopsakars (2005–2012)

    OpenAIRE

    Afanasjeva, Elīna

    2013-01-01

    Šī bakalaura darba tēma ir “Rīgas sociālās vides reklāmas ietekme uz auditoriju: ētikas un efektivitātes kopsakars (2005–2012)”. Darbā izmantoti vides reklāmas piemēri, kuri izstrādāti un izplatīti Rīgā laika posmā no 2005. līdz 2012. gadam. Pētnieciskā problēma: reklāmas ētiskuma korelācija ar sociālās reklāmas ietekmi uz auditoriju un tās komunikatīvo efektivitāti. Pētījuma objekts un priekšmets – sociālā vides reklāma un tās ētikas kopsakars ar ietekmi uz auditoriju. Pētījuma l...

  4. Interneta sociālie tīkli draugiem.lv, mammam/tetiem.lv un twitter.com kā reklāmas nesēji Latvijā (2009.gads)

    OpenAIRE

    Vismane, Inese

    2010-01-01

    Maģistra darba tēma ir „Interneta sociālie tīkli draugiem.lv, mammam/tetiem.lv un twitter.com kā reklāmas nesēji Latvijā (2009.gads)”. Darba mērķis ir izpētīt Latvijas interneta sociālo tīklu vidi kā potenciāli augošu un reklāmai piemērotu, kā arī izpētīt pamanāmākos reklāmas gadījumus šajos portālos. Teorijas daļā tiek apskatīta Web 2.0 ēra, interneta reklāmas un sociālo mediju mārketinga īpatnības, sociālo tīklu fenomens un teorijas, Latvijas reklāmas tirgus un auditorija, kā arī sociāl...

  5. Effect of organic matter application on CP-MAS-13C-NMR spectra of humic acids from a brown soil

    Science.gov (United States)

    Dou, S.

    2009-04-01

    The humified SOM or humic substances (HS) composed of humic acid (HA), fulvic acid (FA) and humin (HM) represent the most microbially recalcitrant and stable reservoir of organic carbon in soil (Piccolo et al., 2004). OM applications can influence the amount and structural characteristics of HS(Dou et al., 2008). During the past few decades, there has been much research on HS, but their chemical structure is still not fully understood (Dong, 2006).CP-MAS-13C-NMR spectroscopy was considered as an effective method to study structures of HS without dissolving problem compared with liquid 13C-NMR (Conte et al., 1997; Dou et al., 2008). It can directly measure the carbon framework and reflect the nature of HS transformation after OM application (Spaccini et al., 2000). For that reason, this method was applied in this study. The objective of this paper was to clarify the effect of long term OM application on the changes of structural characteristics in HAs, which provided new information for improving soil fertility by OM application. The experiment was carried out on a brown soil (Paleudalf in USDA Soil Taxonomy) at Shenyang Agricultural University, Liaoning province, China (N41°48'-E123°25'). The experiment included 3 treatments: zero-treatment (CKbr), and two pig manure (PM) treatments (O1 and O2) at the rates of 0.9 t ha-1 and 1.8 t ha-1 of organic carbon, respectively. The samples of the HA fraction were extracted, separated and purified according to the method described by Dou et al. (1991). Elemental composition, Differential thermal analysis (DTA), -lgK value, FT-IR and CP-MAS- 13C-NMR of HAs were performed. Effects on the contents of orgaic carbon and its composition. The contents of TOC were from 8.77 g kg-1 to 12.25 g kg-1. The relative contents in TOC for WSS, HA, and FA were 6.87%, 14.2% and 19.8%. Comparing the CKbr, the contents of WSS, HA and FA for O1 and O2 increased, but relative contents of WSS and FA decreased. The content of the HA increased after

  6. Turizm Yapılarında Kimlik Sorunu ve Belek-Kemer Örnekleme Çalışması

    Directory of Open Access Journals (Sweden)

    Ş. G. BEYHAN

    2009-04-01

    Full Text Available Turizmin sosyal, kültürel ve ekonomik yapısında meydana gelen değişimler, turistik açıdan gelişen bölgelerin çevresel karakterini etkilemekte; bu bağlamda, turizm alanına hizmet eden turizm yapılarını da etki alanı içine almaktadır. Bu değişimler sonucunda, bir “Turizm Mimarisi” ve “Kimlik Sorunu” ortaya çıkmaktadır. Bu çalışma, böylesi bir yaklaşımla Türkiye'de gelişmekte olan turizm sektörünün bir yan kolu olan konaklama işletmelerinin radikal bir biçimde etkilendiği ve turizm mimarisinde bir “Kimlik Kaosu” yaşandığı gerçeği göz önünde bulundurularak yapılmıştır. Çalışma sürecinde, “Turizm Yapılarında Yaşanan Kimlik Sorunu”, turizm olgusu ve kimlik kavramı bağlamında ele alınmıştır. Turizm yapılarını; özellikle tatil köylerini etkisi altına alan mimari akımlar aracılığı ile uygulanan tasarım yaklaşımları saptanarak, Belek ve Kemer'de yapılan alan çalışması sonuçları ile birleştirilerek, sorun tüm yönleri ile irdelenmeye çalışılmıştır. Çalışmada şu anki durumun tespiti yapılmış, incelenen tesisler, görsel verilerle ifade edilmiş ve bundan sonra inşa edilecek olan turizm yapılarının kimliğini etkileyecek etmenlerle ilgili sorgulamalar yapılmıştır. Çalışmanın temel amaçlarından biri turizm mimarisinde genel olarak yaşanan sorunun çok boyutlu yapısının aktarılmasıdır. Örnekleme çalışması ile problemin turizm ve ülke mimarisini ne derece etkilediği açık bir şekilde gösterilmiş soruna dair bilincin artırılması ve daha duyarlı bir yaklaşım sağlanması amaçlanmıştır.

  7. Differential Regulation of Mas-Related G Protein-Coupled Receptor X2-Mediated Mast Cell Degranulation by Antimicrobial Host Defense Peptides and Porphyromonas gingivalis Lipopolysaccharide.

    Science.gov (United States)

    Gupta, Kshitij; Idahosa, Chizobam; Roy, Saptarshi; Lee, Donguk; Subramanian, Hariharan; Dhingra, Anuradha; Boesze-Battaglia, Kathleen; Korostoff, Jonathan; Ali, Hydar

    2017-10-01

    Porphyromonas gingivalis is a keystone pathogen that contributes to periodontal pathogenesis by disrupting host-microbe homeostasis and promoting dysbiosis. The virulence of P. gingivalis likely reflects an alteration in the lipid A composition of its lipopolysaccharide (LPS) from the penta-acylated ( Pg LPS 1690 ) to the tetra-acylated ( Pg LPS 1435/1449 ) form. Mast cells play an important role in periodontitis, but the mechanisms of their activation and regulation remain unknown. The expression of epithelium- and neutrophil-derived host defense peptides (HDPs) (LL-37 and human β-defensin-3), which activate mast cells via Mas-related G protein-coupled receptor X2 (MRGPRX2), is increased in periodontitis. We found that MRGPRX2-expressing mast cells are present in normal gingiva and that their numbers are elevated in patients with chronic periodontitis. Furthermore, HDPs stimulated degranulation in a human mast cell line (LAD2) and in RBL-2H3 cells stably expressing MRGPRX2 (RBL-MRGPRX2). Pg LPS 1690 caused substantial inhibition of HDP-induced mast cell degranulation, but Pg LPS 1435/1449 had no effect. A fluorescently labeled HDP (FAM-LL-37) bound to RBL-MRGPRX2 cells, and Pg LPS 1690 inhibited this binding, but Pg LPS 1435/1449 had no effect. These findings suggest that low-level inflammation induced by HDP/MRGPRX2-mediated mast cell degranulation contributes to gingival homeostasis but that sustained inflammation due to elevated levels of both HDPs and MRGPRX2-expressing mast cells promotes periodontal disease. Furthermore, differential regulation of HDP-induced mast cell degranulation by Pg LPS 1690 and Pg LPS 1435/1449 may contribute to the modulation of disease progression. Copyright © 2017 American Society for Microbiology.

  8. Medical Imaging Teacher: A program to simulate X-ray images of the body by considering kVp, mAs and FFD values

    Directory of Open Access Journals (Sweden)

    Umit Kara

    2017-06-01

    Full Text Available Introduction: Teaching styles and methods have been constantly changing in the recent years. In the 1980s and 90s, the world was introduced to various developed devices, such as smart boards and early generation smart phones that had an immediate innovative effect on education. These advancements has resulted in a considerable improvement in the current educational techniques. The innovations in medical techniques and their quality is of paramount importance. The aim of this study was to provide an innovative and useful software on radiological applications and contribute to the related literature. Materials and Methods: The Medical Imaging Teacher (MIT program was created and the prototype application was implemented on the Android platform for free use. The programing and testing of the usability of the application were performed by the users of the Google Play Store. Results: In this program, we have developed new software to simulate the X-ray images of the body by considering the peak kilovoltage (kVp, milliamperage per second (mAs, and film focus distance (FFD values. The application has been downloaded more than 1,000 times without paid advertising. We enrolled 131 participants, who made comments and gave 4.8 points on average. Conclusion: It can be concluded that with innovative digital programs, such as the MIT, the medical machine-based learning and medical applications have risen to new levels. The software on medical testing and examination is gaining increasing popularity among the health-related applications for smart phones.

  9. Effect of Mas-related gene (Mrg) receptors on hyperalgesia in rats with CFA-induced inflammation via direct and indirect mechanisms.

    Science.gov (United States)

    Jiang, Jianping; Wang, Dongmei; Zhou, Xiaolong; Huo, Yuping; Chen, Tingjun; Hu, Fenjuan; Quirion, Rémi; Hong, Yanguo

    2013-11-01

    Mas oncogene-related gene (Mrg) receptors are exclusively distributed in small-sized neurons in trigeminal and dorsal root ganglia (DRG). We investigated the effects of MrgC receptor activation on inflammatory hyperalgesia and its mechanisms. A selective MrgC receptor agonist, bovine adrenal medulla peptide 8-22 (BAM8-22) or melanocyte-stimulating hormone (MSH) or the μ-opioid receptor (MOR) antagonist CTAP was administered intrathecally (i.t.) in rats injected with complete Freund's adjuvant (CFA) in one hindpaw. Thermal and mechanical nociceptive responses were assessed. Neurochemicals were measured by immunocytochemistry, Western blot, ELISA and RT-PCR. CFA injection increased mRNA for MrgC receptors in lumbar DRG. BAM8-22 or MSH, given i.t., generated instant short and delayed long-lasting attenuations of CFA-induced thermal hyperalgesia, but not mechanical allodynia. These effects were associated with decreased up-regulation of neuronal NOS (nNOS), CGRP and c-Fos expression in the spinal dorsal horn and/or DRG. However, i.t. administration of CTAP blocked the induction by BAM8-22 of delayed anti-hyperalgesia and inhibition of nNOS and CGRP expression in DRG. BAM8-22 also increased mRNA for MORs and pro-opiomelanocortin, along with β-endorphin content in the lumbar spinal cord and/or DRG. MrgC receptors and nNOS were co-localized in DRG neurons. Activation of MrgC receptors suppressed up-regulation of pronociceptive mediators and consequently inhibited inflammatory pain, because of the activation of up-regulated MrgC receptors and subsequent endogenous activity at MORs. The uniquely distributed MrgC receptors could be a novel target for relieving inflammatory pain. © 2013 The British Pharmacological Society.

  10. Analysis of mercerization process based on the intensity change of deconvoluted resonances of 13C CP/MAS NMR: Cellulose mercerized under cooling and non-cooling conditions

    International Nuclear Information System (INIS)

    Miura, Kento; Nakano, Takato

    2015-01-01

    The area intensity change of C1, C4, and C6 in spectrum obtained by 13 C CP/MAS NMR and the mutual relationship between their changes were examined for cellulose samples treated with various concentrations of aqueous NaOH solutions under non-cooling and cooling conditions. The area intensity of C1-up and C6-down changed cooperatively with that of C4-down which corresponds to the crystallinity of samples: “-up” and “-down” are the up- and down- field component in a splitting peak of NMR spectrum, respectively. The intensity change of C1-up starts to decrease with decreasing in that of C4-down after that of C6-down is almost complete. These changes were more clearly observed for samples treated under cooling condition. It can be suggested that their characteristic change relates closely to the change in conformation of cellulose chains by induced decrystallization and the subsequent crystallization of cellulose II, and presumed that their changes at microscopic level relate to the macroscopic morphological changes such as contraction along the length of cellulose chains and recovery along the length. - Highlight: • Samples were mercerized at various NaOH concentrations under non-cooling and cooling. • The intensity change of C1 starts immediately after that of C6 is complete. • The creation of cell-II starts when decrystallization proceeds to a certain state. • This change relates closely to the change in conformation of cellulose chains. • The above change is more clearly found for samples treated under cooling

  11. Emerging Roles for MAS-Related G Protein-Coupled Receptor-X2 in Host Defense Peptide, Opioid, and Neuropeptide-Mediated Inflammatory Reactions.

    Science.gov (United States)

    Ali, Hydar

    2017-01-01

    Mast cells (MCs) are tissue-resident immune cells that contribute to host defense but are best known for their roles in allergic and inflammatory diseases. In humans, MCs are divided into two subtypes based on the protease content of their secretory granules. Thus, human lung MCs contain only tryptase and are known as MC T , whereas skin MCs contain both tryptase and chymase and are known as MC TC . Patients with severe asthma display elevated MCs in the lung, which undergo phenotypic change from MC T to MC TC . Although the human genome contains four Mas related G protein coupled receptor X (MRGPRX) genes, an important feature of MC TC is that they selectively express MRGPRX2. It is activated by antimicrobial host defense peptides such as human β-defensins and the cathelicidin LL-37 and likely contributes to host defense. MRGPRX2 is also a receptor for the neuropeptide substance P, major basic protein, eosinophil peroxidase, opioids, and many FDA-approved cationic drugs. Increased expression of MRGPRX2 or enhanced downstream signaling likely contributes to chronic inflammatory diseases such as rosacea, atopic dermatitis, chronic urticaria, and severe asthma. In this chapter, I will discuss the expression profile and function of MRGPRX1-4 and review the emerging roles of MRGPRX2 on host defense, chronic inflammatory diseases, and drug-induced pseudoallergic reactions. I will also examine the novel aspects of MRGPRX2 signaling in MCs as it related to degranulation and review the mechanisms of its regulation. © 2017 Elsevier Inc. All rights reserved.

  12. RESILIENCY OF SMALL-SCALE COMMON CARP (Cyprinus carpio FARMERS IN WEST PAGADEN RURAL AREA OF SUBANG - WEST JAVA (Daya Lenting Pembudidaya Ikan Mas (Cyprinus carpio Skala Kecil di Perdesaan Kecamatan Pagaden Barat Subang – Jawa Barat

    Directory of Open Access Journals (Sweden)

    Carolina Carolina

    2015-03-01

    Full Text Available ABSTRACT Since early 1980s, freshwater fish farming was introduced as an economic activity to the rural community in Subang, West Java Province. Until presently, 5% of the population participate on it, specifically as common carp (Cyprinus carpio cultivators in freshwater ponds ecosystem. The economic gain from the carp farming triggers vast development indicated by significant landscape conversion from rice fields to fish ponds. Environmental limitation does not seem to become their major concern, because good yields which means good income is their main driving factor to extend and intensify common carp aquaculture. Recognizing the important role of small scale fish farms in West Java common carp production system, we explore their resiliency in confronting challenges encountered in managing the freshwater ecosystem. Utilizing participatory observation and interview, we explore their socio-ecological resilience from the perception of human and nature interaction. The study area is Pagaden Sub District in Subang - West Java. Descriptive analysis is used to articulate the phenomenon enfolded in a socio-ecological framework of thinking. It can be concluded that high dependency to the aquaculture activity, has reached a situation in which ecologically sound technology should be introduced. Included in a scheme of technical assistance which specifically designed to meet the need and in harmony with the socio-cultural characters of small-scale fish farmers, the technology introduction should be carried out to spur the sustainable aquaculture in Subang West Java. This should be a proposed agenda for the local government in support to aquaculture sustainable development. ABSTRAK Sejak awal tahun 1980, budidaya ikan air tawar diperkenalkan sebagai kegiatan ekonomi masyarakat desa di wilayah Subang, Propinsi Jawa Barat. Dewasa ini, sekitar 5% populasi terlibat di kegiatan tersebut, terutama sebagai pembudidaya ikan mas (Cyprinus carpio di ekosistem

  13. Virālo video izmantošana Latvijas reklāmas kampaņās: "Piens Fest", "Kiwie" un "AirDog" gadījumi

    OpenAIRE

    Manuilova, Santa

    2015-01-01

    Bakalaura darba tēma ir „Virālo video izmantošana Latvijas reklāmas kampaņās: „Piens Fest”, „Kiwie” un „AirDog” gadījumi”. Pētījuma mērķis - noskaidrot virālo video reklāmu izmantošanas tendences Latvijā un noteikt, kāda ir auditorijas attieksme pret šādiem video. Darbā tika izmantotas kvantitatīvā un kvalitatīvā pētījumu metodes: aptauja un intervija. Teorētiskajā pamatojumā apskatīta mediju konverģences teorija, jauno mediju, reklāmas kampaņu un partizānu mārketinga teorētiskais ra...

  14. Vērtību arhetipu izmantošana vides reklāmu saturā: 2008. - 2011. gada vides reklāmas piemēru analīze

    OpenAIRE

    Grīna, Baiba

    2012-01-01

    Bakalaura darba „Vērtību arhetipu izmantošana vides reklāmu saturā: 2008. - 2011. gada vides reklāmas piemēru analīze” mērķis ir izpētīt vērtību arhetipu izmantošanu vides reklāmu saturā, lai noskaidrotu arhetipu identificējās ar sabiedrību caur vides reklāmu saturu. Bakalaura darba teorētiskā pieeja balstīta uz K. G. Junga bezapziņas koncepta un arhetipu teoriju, kā arī uz M. Markas un K. Pīrsones izstrādāto reklāmas arhetipu sistēmu. Tā pat darbā ir apskatīta arī vides reklāmu teorija. ...

  15. Out-and-back {sup 13}C-{sup 13}C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS

    Energy Technology Data Exchange (ETDEWEB)

    Barbet-Massin, Emeline; Pell, Andrew J. [University of Lyon, CNRS/ENS Lyon/UCB Lyon 1, Centre de RMN a Tres Hauts Champs (France); Jaudzems, Kristaps [Latvian Institute of Organic Synthesis (Latvia); Franks, W. Trent; Retel, Joren S. [Leibniz-Institut fuer Molekulare Pharmakologie (Germany); Kotelovica, Svetlana; Akopjana, Inara; Tars, Kaspars [Biomedical Research and Study Center (Latvia); Emsley, Lyndon [University of Lyon, CNRS/ENS Lyon/UCB Lyon 1, Centre de RMN a Tres Hauts Champs (France); Oschkinat, Hartmut [Leibniz-Institut fuer Molekulare Pharmakologie (Germany); Lesage, Anne; Pintacuda, Guido, E-mail: guido.pintacuda@ens-lyon.fr [University of Lyon, CNRS/ENS Lyon/UCB Lyon 1, Centre de RMN a Tres Hauts Champs (France)

    2013-08-15

    We present here {sup 1}H-detected triple-resonance H/N/C experiments that incorporate CO-CA and CA-CB out-and-back scalar-transfer blocks optimized for robust resonance assignment in biosolids under ultra-fast magic-angle spinning (MAS). The first experiment, (H)(CO)CA(CO)NH, yields {sup 1}H-detected inter-residue correlations, in which we record the chemical shifts of the CA spins in the first indirect dimension while during the scalar-transfer delays the coherences are present only on the longer-lived CO spins. The second experiment, (H)(CA)CB(CA)NH, correlates the side-chain CB chemical shifts with the NH of the same residue. These high sensitivity experiments are demonstrated on both fully-protonated and 100 %-H{sup N} back-protonated perdeuterated microcrystalline samples of Acinetobacter phage 205 (AP205) capsids at 60 kHz MAS.

  16. Expression and distribution patterns of Mas-related gene receptor subtypes A-H in the mouse intestine: inflammation-induced changes.

    Science.gov (United States)

    Avula, Leela Rani; Buckinx, Roeland; Favoreel, Herman; Cox, Eric; Adriaensen, Dirk; Van Nassauw, Luc; Timmermans, Jean-Pierre

    2013-05-01

    Mas-related gene (Mrg) receptors constitute a subfamily of G protein-coupled receptors that are implicated in nociception, and are as such considered potential targets for pain therapies. Furthermore, some Mrgs have been suggested to play roles in the regulation of inflammatory responses to non-immunological activation of mast cells and in mast cell-neuron communication. Except for MrgD, E and F, whose changed expression has been revealed during inflammation in the mouse intestine in our earlier studies, information concerning the remaining cloned mouse Mrg subtypes in the gastrointestinal tract during (patho) physiological conditions is lacking. Therefore, the present study aimed at identifying the presence and putative function of these remaining cloned Mrg subtypes (n = 19) in the (inflamed) mouse intestine. Using reverse transcriptase-PCR, quantitative-PCR and multiple immunofluorescence staining with commercial and newly custom-developed antibodies, we compared the ileum and the related dorsal root ganglia (DRG) of non-inflamed mice with those of two models of intestinal inflammation, i.e., intestinal schistosomiasis and 2,4,6-trinitrobenzene sulfonic acid-induced ileitis. In the non-inflamed ileum and DRG, the majority of the Mrg subtypes examined were sparsely expressed, showing a neuron-specific expression pattern. However, significant changes in the expression patterns of multiple Mrg subtypes were observed in the inflamed ileum; for instance, MrgA4, MrgB2and MrgB8 were expressed in a clearly increased number of enteric sensory neurons and in nerve fibers in the lamina propria, while de novo expression of MrgB10 was observed in enteric sensory neurons and in newly recruited mucosal mast cells (MMCs). The MrgB10 expressing MMCs were found to be in close contact with nerve fibers in the lamina propria. This is the first report on the expression of all cloned Mrg receptor subtypes in the (inflamed) mouse intestine. The observed changes in the expression and

  17. I: Low Frequency NMR and NQR Using a dc SQUID. II: Variable-temperature 13C CP/MAS of Organometallics

    Energy Technology Data Exchange (ETDEWEB)

    Ziegeweid, Marcia A. [Univ. of California, Berkeley, CA (United States)

    1995-11-01

    NMR and NQR at low frequencies are difficult prospects due to small nuclear spin polarization. Furthermore, the sensitivity of the inductive pickup circuitry of standard spectrometers is reduced as the frequency is lowered. I have used a cw-SQUID (Superconducting Quantum Interference Device) spectrometer, which has no such frequency dependence, to study the local atomic environment of 14N via the quadrupolar interaction. Because 14N has spin I = 1 and a 0-6 MHz frequency range, it is not possible to obtain well-resolved spectra in high magnetic fields. I have used a technique to observe 14N NQR resonances via their effect on neighboring protons mediated by the heteronuclear dipolar interaction to study peptides and narcotics. The sensitivity of the SQUID is not enough to measure low-frequency surface (or other low spin density) systems. The application of spin-polarized xenon has been previously used to enhance polarization in conventional NMR experiments. Because xenon only polarizes spins with which it is in contact, it is surface selective. While differences in chemical shifts between surface and bulk spins are not large, it is expected that the differences in quadrupole coupling constant should be very large due to the drastic change of the electric field gradient surrounding spins at the surface. With this in mind, I have taken preliminary steps to measure SQUID detected polarization transfer from Xe to another spin species at 4.2 K and in small magnetic fields (<50 G). In this regime, the spin-lattice relaxation of xenon is dependent on the applied magnetic field. The results of our efforts to characterize the relaxation of xenon are presented. The final section describes the solid-state variable-temperature (VT) one- and two-dimensional 13C cross polarization (CP)/magic angle spinning (MAS) NMR of Hf(η5-C5H5)21-C5H5)2, Zr

  18. Reversal of neurochemical alterations in the spinal dorsal horn and dorsal root ganglia by Mas-related gene (Mrg) receptors in a rat model of spinal nerve injury.

    Science.gov (United States)

    Wang, Dongmei; Xue, Yaping; Yan, Yanhua; Lin, Minjie; Yang, Jiajia; Huang, Jianzhong; Hong, Yanguo

    2016-07-01

    The rodent Mas-related gene (Mrg) receptor subtype C has been demonstrated to inhibit pathological pain. This study investigated the mechanisms underlying the reversal of pain hypersensitivity by the selective MrgC receptor agonist bovine adrenal medulla 8-22 (BAM8-22) in a rat model of L5 spinal nerve ligation (SNL). Intrathecal (i.t.) administration of BAM8-22 (0.1-10nmol) attenuated mechanical allodynia in a dose-dependent manner on day 10 after SNL. The antiallodynia effect of BAM8-22 was abolished by MrgC receptor antibody, but not by naloxone. I.t. BAM8-22 (10nmol) inhibited SNL-induced upregulation of neuronal nitric oxide synthesis (nNOS) and phosphorylation of cyclic AMP response element-binding protein (p-CREB) in the spinal dorsal horn. The BAM8-22 treatment reversed the SNL-induced astrocyte activation, increase of interleukin-1β (IL-1β) expression and phosphorylation of extracellular signal-regulated kinase (p-ERK) in the spinal cord. BAM8-22 also reversed the upregulation of fractalkine and IL-1β in small- and medium-sized dorsal root ganglion (DRG) neurons. Furthermore, the BAM8-22 exposure suppressed the lipopolysaccharide (LPS)-induced increase of nNOS and IL-1β in the DRG explant cultures and the BAM8-22-induced suppression disappeared in the presence of MrgC receptor antibody. The present study provides evidence that activation of MrgC receptors inhibits nerve injury-induced increase of pronociceptive molecules in DRG neurons, suppressing astrocyte activation, the upregulation of excitatory mediators and phosphorylation of transcription factors in the spinal dorsal horn. As MrgC receptors are unequally expressed in the dorsal root and trigeminal ganglia, this study suggests that targeting MrgC receptors could be a new therapy for neuropathic pain with limited unwanted effects. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Solid state {sup 31}P MAS NMR spectroscopy and conductivity measurements on NbOPO{sub 4} and H{sub 3}PO{sub 4} composite materials

    Energy Technology Data Exchange (ETDEWEB)

    Risskov Sørensen, Daniel [Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Niels Bohrs Allé 1, 5230 Odense M (Denmark); Nielsen, Ulla Gro [Department of Physics, Chemistry and Pharmacy, Campusvej 55, University of Southern Denmark, 5230 Odense M (Denmark); Skou, Eivind M., E-mail: ems@kbm.sdu.dk [Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Niels Bohrs Allé 1, 5230 Odense M (Denmark)

    2014-11-15

    A systematic study of composite powders of niobium oxide phosphate (NbOPO{sub 4}) and phosphoric acid (H{sub 3}PO{sub 4}) has been performed in order to characterize the material's ability to perform as an electrolyte material in medium temperature fuel cells and electrolyzers. Powders of H{sub 3}PO{sub 4} contents between 13.1 and 74.2 M% were produced and characterized with powder X-ray diffraction, {sup 31}P MAS NMR and impedance spectroscopy. NMR revealed that a significant degree of dehydration and vaporization of H{sub 3}PO{sub 4} takes place above 200 °C, and increases with temperature. At 500 °C the NbOPO{sub 4} and H{sub 3}PO{sub 4} has reacted to form niobium pyrophosphate (Nb{sub 2}P{sub 4}O{sub 15}). Impedance spectroscopy showed an increase in conductivity with increasing acid concentration, whereas the conductivity decreased slightly with increasing temperature. The highest conductivity measured was 2.5·10{sup −3} S/cm for a sample containing 74.2 M% of H{sub 3}PO{sub 4}. Lastly, it was shown that NbOPO{sub 4} has no significant conductivity of its own. - Graphical abstract: Conductivity of NbOPO{sub 4}/H{sub 3}PO{sub 4} composites as a function of equivalent P{sub 2}O{sub 5} content. The conductivity is insignificant for pure NbOPO{sub 4}. - Highlights: • Composites have been made from NbOPO{sub 4} and H{sub 3}PO{sub 4}. • The composites composition has been investigated with solid state NMR. • The composites have shown clear signs of acid dehydration upon heating. • The conductivity of the composites increases for increasing acid content. • NbOPO{sub 4} has no significant conductivity of its own.

  20. {sup 1}H and {sup 23}Na MAS NMR spectroscopy of cationic species in CO{sub 2} selective alkaline earth metal porous silicoaluminophosphates prepared via liquid and solid state ion exchange

    Energy Technology Data Exchange (ETDEWEB)

    Arevalo-Hidalgo, Ana G. [Department of Chemical Engineering, University of Puerto Rico-Mayagueez Campus, Mayagueez, PR 00681-9000 (Puerto Rico); Dugar, Sneha; Fu, Riqiang [National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310 (United States); Hernandez-Maldonado, Arturo J., E-mail: arturoj.hernandez@upr.edu [Department of Chemical Engineering, University of Puerto Rico-Mayagueez Campus, Mayagueez, PR 00681-9000 (Puerto Rico)

    2012-07-15

    The location of extraframework cations in Sr{sup 2+} and Ba{sup 2+} ion-exchanged SAPO-34 was estimated by means of {sup 1}H and {sup 23}Na MAS NMR spectroscopy and spectral deconvolution. Incorporation of the alkaline earth metal cations onto the SAPO framework was achieved via liquid state ion exchange, coupled partial detemplation/solid-state ion exchange, and combination of both techniques. MAS NMR revealed that the level of ion exchange was limited by the presence of protons and sodium cations near hexagonal prisms (site SI), which are relatively difficult to exchange with the alkaline earth metal due to steric and charge repulsion criteria. In addition, the presence of ammonium cations in the supercages facilitated the exchange of otherwise tenacious hydrogen as corroborated by unit cell compositional data as well as enhanced CO{sub 2} adsorption at low partial pressures. The extraframework ammonium species were produced from partial detemplation of the structure-directing agent employed for the SAPO-34 synthesis, tetraethylammonium. - Graphical abstract: MAS NMR was used to elucidate the position the cationic species in alkaline earth metal exchanged silicoaluminophosphates. These species played a significant role during the ion exchange process and, therefore, the materials ultimate CO{sub 2} adsorption performance. Highlights: Black-Right-Pointing-Pointer Location of extraframework Sr{sup 2+} or Ba{sup 2+} cations was estimated by means of {sup 1}H and {sup 23}Na MAS NMR. Black-Right-Pointing-Pointer Level of Sr{sup 2+} or Ba{sup 2+} ion exchange was limited by the presence of protons and sodium cations. Black-Right-Pointing-Pointer Presence of ammonium cations in the supercages facilitated the exchange. Black-Right-Pointing-Pointer Sr{sup 2+} and Ba{sup 2+} ion exchanged SAPOs are outstanding CO{sub 2} adsorbents.

  1. Effect of Ge/Si substitutions on the local geometry of Si framework sites in zeolites: A combined high resolutionsup29/supSi MAS NMR and DFT/MM study on zeolite Beta polymorph C (BEC)

    Czech Academy of Sciences Publication Activity Database

    Whittleton, Sarah R.; Vicente, A.; Fernandez, C.; Rastegar, Somayeh F.; Fishchuk, Anna V.; Sklenák, Štěpán

    2018-01-01

    Roč. 267, SEP 2018 (2018), s. 124-133 ISSN 1387-1811 R&D Projects: GA ČR(CZ) GA15-14007S Grant - others:Ga MŠk(CZ) LM2015070 Institutional support: RVO:61388955 Keywords : 29 Si MAS NMR * bec * Ge-zeolites * Germanoaluminosilicates * Zeolite Beta polymorph C Subject RIV: CF - Physical ; Theoretical Chemistry OBOR OECD: Physical chemistry Impact factor: 3.615, year: 2016

  2. Coaliciones y traiciones masónicas. De la primera reelección de Porfirio Díaz a los inicios de la revolución mexicana, 1887-1911

    Directory of Open Access Journals (Sweden)

    Carlos Francisco Martínez Moreno

    2015-01-01

    Full Text Available En México desde la primera reelección en la presidencia del general Porfirio Díaz en 1887 hasta su salida en1911 en los inicios de la revolución mexicana varios grupos disputaron por el poder político, en estainvestigación se busca mostrar que durante ese período diferentes procesos electorales, movimientos socialesy revolucionarios fueron el resultado de coaliciones y de traiciones masónicas.

  3. One-Pot Synthesis, X-Ray Diffraction and MAS NMR Spectroscopic Study of Gallosilicate Nitrate Cancrinite Na8[GaSiO4]6(NO34(H2O6

    Directory of Open Access Journals (Sweden)

    Ashok V. Borhade

    2010-01-01

    Full Text Available One-pot synthetic gallosilicate nitrate cancrinite (CAN framework topology have been synthesized under hydrothermal conditions at 100 °C. The synthesized product was characterized by, X-ray powder diffraction, IR, Raman and 29Si, 23Na MAS NMR spectroscopy, SEM and thermogravimetry. The crystal structure refinement of pure nitrate cancrinite has been carried out from X-ray data using Rietveld refinement method. Gallosilicate cancrinite Na8[GaSiO4]6(NO34(H2O6 crystalline hexagonal with space group P63 and a = 12.77981 Å (2, c = 5.20217 Å (1, (Rwp = 0.0696 Rp = 0.0527. The results by MAS NMR spectroscopy confirmed the alternating Si, Ga ordering of the gallosilicate framework for a Si/Ga ratio of 1.0. A distribution of the quadrupolar interaction of the sodium cations caused by the enclatherated water molecules and motional effects can be suggested from the 23Na MAS NMR. Thermogravimetric investigation shows the extent of nitrate entrapment, stability within the cancrinite cage and decomposition properties. SEM clearly shows the hexagonal needle shaped crystals of nitrate cancrinite.

  4. Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.

    Science.gov (United States)

    Hampl, V; Herget, J; Bíbová, J; Baňasová, A; Husková, Z; Vaňourková, Z; Jíchová, Š; Kujal, P; Vernerová, Z; Sadowski, J; Červenka, L

    2015-01-01

    The present study was performed to evaluate the role of intrapulmonary activity of the two axes of the renin-angiotensin system (RAS): vasoconstrictor angiotensin-converting enzyme (ACE)/angiotensin II (ANG II)/ANG II type 1 receptor (AT₁) axis, and vasodilator ACE type 2 (ACE2)/angiotensin 1-7 (ANG 1-7)/Mas receptor axis, in the development of hypoxic pulmonary hypertension in Ren-2 transgenic rats (TGR). Transgene-negative Hannover Sprague-Dawley (HanSD) rats served as controls. Both TGR and HanSD rats responded to two weeks´ exposure to hypoxia with a significant increase in mean pulmonary arterial pressure (MPAP), however, the increase was much less pronounced in the former. The attenuation of hypoxic pulmonary hypertension in TGR as compared to HanSD rats was associated with inhibition of ACE gene expression and activity, inhibition of AT₁receptor gene expression and suppression of ANG II levels in lung tissue. Simultaneously, there was an increase in lung ACE2 gene expression and activity and, in particular, ANG 1-7 concentrations and Mas receptor gene expression. We propose that a combination of suppression of ACE/ANG II/AT₁receptor axis and activation of ACE2/ANG 1-7/Mas receptor axis of the RAS in the lung tissue is the main mechanism explaining attenuation of hypoxic pulmonary hypertension in TGR as compared with HanSD rats.

  5. Condensed aromatic rings and E{sub 4}/E{sub 6} ratio: humic acids in gleysoils studied by NMR CP/MAS{sup 13}C, and dipolar dephasing; Aneis aromaticos condensados e relacao E{sub 4}/E{sub 6}: estudo de acidos humicos de gleissolos por RMN de {sup 13}C no estado solido utilizando a tecnica CP/MAS desacoplamento defasado

    Energy Technology Data Exchange (ETDEWEB)

    Saab, Sergio da Costa [Universidade Estadual de Ponta Grossa, PR (Brazil). Dept. de Fisica]. E-mail: scsaab@uepg.br; Martin-Neto, Ladislau [Empresa Brasileira de Pesquisa Agropecuaria, Sao Carlos, SP (Brazil)

    2007-03-15

    In this work, seven samples of humic acids extracted from gleysoils were investigated. These studies, using NMR CP/MAS {sup 13}C techniques, did not show significant correlation between the E{sub 4}/E{sub 6} ratio and the degree of aromaticity. However, dipolar dephasing (DD) measurements of condensed aromatic or substituted carbons showed a negative correlation of 0.94. Also, there was a good correlation between the amount of semiquinone free radicals measured by the EPR technique and condensed aromatic rings measured by NMR CP/MAS {sup 13}C with the DD technique. The content of semiquinone free radicals was quantified by EPR spectroscopy and was correlated with the humification (degree of aromaticity) of the humic substances. The results indicated that the E{sub 4}/E{sub 6} ratio identifies the degree of aromatic rings condensation. It was also found that the degree of aromaticity, measured by NMR, as frequently presented in the literature (by conventional CP/MAS), underestimates aromatic rings in condensed structures. (author)

  6. BN interphase in composite materials with nicalon Si-C-O fibers and with vitro ceramic matrix of MAS type; L`interphase BN dans les materiaux composites a fibres Si-C-O nicalon et a matrice vitroceramique de type MAS

    Energy Technology Data Exchange (ETDEWEB)

    Ricca, N.

    1994-03-14

    BN has been suggested as an interphase in silica-based glass-ceramic matrix composites with a view to use these materials in oxidizing atmospheres at medium or high temperatures. The matrix had a boron-doped MAS (MgO-Al{sub 2}O{sub 3}-SiO{sub 2}) composition and was prepared from an hydrosol precursor. Pseudo-ID composites were prepared according to a sol impregnations/calcination/hot-pressing route. Chemical and microstructural characterizations of the fiber/matrix interfacial area were conducted by mean of TEM/EELS and AES analyses. The efficiency of BN as a coupling interphase for this particular composite system was successfully demonstrated through tensile tests performed on either as-processed or aged specimens (100 hours at 1000 deg C in air or under argon). In addition, composites maintained in air at 600 deg C, 800 deg C and 900 deg C while simultaneously loaded did not fail after 150 hours or more. Thus, a BN interphase appeared to be compatible with an oxidizing environment (i.e. the oxide matrix and/or air from 600 to 1000 deg C) and should therefore successfully replace the usual carbon interphase at least for use at medium temperatures. (author)

  7. QuBiLS-MAS, open source multi-platform software for atom- and bond-based topological (2D) and chiral (2.5D) algebraic molecular descriptors computations.

    Science.gov (United States)

    Valdés-Martiní, José R; Marrero-Ponce, Yovani; García-Jacas, César R; Martinez-Mayorga, Karina; Barigye, Stephen J; Vaz d'Almeida, Yasser Silveira; Pham-The, Hai; Pérez-Giménez, Facundo; Morell, Carlos A

    2017-06-07

    In previous reports, Marrero-Ponce et al. proposed algebraic formalisms for characterizing topological (2D) and chiral (2.5D) molecular features through atom- and bond-based ToMoCoMD-CARDD (acronym for Topological Molecular Computational Design-Computer Aided Rational Drug Design) molecular descriptors. These MDs codify molecular information based on the bilinear, quadratic and linear algebraic forms and the graph-theoretical electronic-density and edge-adjacency matrices in order to consider atom- and bond-based relations, respectively. These MDs have been successfully applied in the screening of chemical compounds of different therapeutic applications ranging from antimalarials, antibacterials, tyrosinase inhibitors and so on. To compute these MDs, a computational program with the same name was initially developed. However, this in house software barely offered the functionalities required in contemporary molecular modeling tasks, in addition to the inherent limitations that made its usability impractical. Therefore, the present manuscript introduces the QuBiLS-MAS (acronym for Quadratic, Bilinear and N-Linear mapS based on graph-theoretic electronic-density Matrices and Atomic weightingS) software designed to compute topological (0-2.5D) molecular descriptors based on bilinear, quadratic and linear algebraic forms for atom- and bond-based relations. The QuBiLS-MAS module was designed as standalone software, in which extensions and generalizations of the former ToMoCoMD-CARDD 2D-algebraic indices are implemented, considering the following aspects: (a) two new matrix normalization approaches based on double-stochastic and mutual probability formalisms; (b) topological constraints (cut-offs) to take into account particular inter-atomic relations; (c) six additional atomic properties to be used as weighting schemes in the calculation of the molecular vectors; (d) four new local-fragments to consider molecular regions of interest; (e) number of lone-pair electrons in

  8. 31P MAS refocused INADEQUATE spin-echo (REINE) NMR spectroscopy: revealing J coupling and chemical shift two-dimensional correlations in disordered solids.

    Science.gov (United States)

    Guerry, Paul; Smith, Mark E; Brown, Steven P

    2009-08-26

    Two-dimensional (2D) variations in (2)J(P(1),P(1)), (2)J(P(1),P(2)), and (2)J(P(2),P(2)) are obtained--using the REINE (REfocused INADEQUATE spin-Echo) pulse sequence presented by Cadars et al. (Phys. Chem. Chem. Phys. 2007, 9, 92-103)--from pixel-by-pixel fittings of the spin-echo modulation for the 2D correlation peaks due to linked phosphate tetrahedra (P(1)-P(1), P(1)-P(2), P(2)-P(1), and P(2)-P(2)) in a (31)P refocused INADEQUATE solid-state MAS NMR spectrum of a cadmium phosphate glass, 0.575CdO-0.425P(2)O(5). In particular, separate variations for each 2D (31)P REINE peak are obtained which reveal correlations between the J couplings and the (31)P chemical shifts of the coupled nuclei that are much clearer than those evident in previously presented 2D z-filtered (31)P spin-echo spectra. Notably, such correlations between the J couplings and the (31)P chemical shifts are observed even though the conditional probability distributions extracted using the protocol of Cadars et al. (J. Am. Chem. Soc. 2005, 127, 4466-4476) indicate that there is no marked correlation between the (31)P chemical shifts of neighboring phosphate tetrahedra. For 2D peaks at the P(2) (31)P chemical shift in the direct dimension, there can be contributions from chains of three units (P(1)-P(2)-P(1)), chains of four units (P(1)-P(2)-P(2)-P(1)), or longer chains or rings (-P(2)-P(2)-P(2)-): for the representative glass considered here, best fits are obtained assuming a glass comprised predominantly of chains of four units. The following variations are found: (2)J(P(1),P(1)) = 13.4 +/- 0.3 to 14.8 +/- 0.5 Hz, (2)J(P(1),P(2)) = 15.0 +/- 0.3 to 18.2 +/- 0.3 Hz, and (2)J(P(2),P(2)) = 5.9 +/- 0.6 to 9.1 +/- 0.9 Hz from the fits to the P(1)-P(1), P(1)-P(2), and P(2)-P(2) peaks, respectively. The correlation of a particular J coupling with the (31)P chemical shifts of the considered nucleus and the coupled nucleus is quantified by the coefficients C(F(2)) and C(F(1)) that correspond to the

  9. Automatic exposure control in pediatric and adult computed tomography examinations: can we estimate organ and effective dose from mean MAS reduction?

    Science.gov (United States)

    Papadakis, Antonios E; Perisinakis, Kostas; Oikonomou, Ismini; Damilakis, John

    2011-10-01

    5-year-old, -62.4% to -17.3% for 10-year-old, and 31.0% to 56.8% for an adult. In neonate, the EDMEAS values ranged from 1.18 to 3.23 mSv for fixed tube current and 1.31 to 1.73 mSv for AEC scans. In 1-year-old phantom, the EDMEAS values ranged from 1.71 to 2.82 mSv for fixed tube current and 0.99 to 2.38 mSv for AEC scans. In 5-year-old phantom, the EDMEAS values ranged from 2.03 to 3.72 mSv for fixed tube current and 1.57 to 3.35 mSv for AEC scans. In 10-year-old phantom, the EDMEAS values ranged from 1.56 to 2.88 mSv for fixed tube current and 1.63 to 3.14 mSv for AEC scans. In adult phantom, the EDMEAS values ranged from 3.39 to 8.06 mSv for fixed tube current and 2.28 to 3.83 mSv for AEC scans. Mean mAs reduction is linearly related to the EDMEAS reduction (r = 0.807, P dose to exposed radiosensitive organs. Moreover, the reduction in the modulated tube current may only be considered as a rough approximation of the corresponding effective dose reduction.

  10. "Faz isso, faz aquilo, mas eu tô caindo...": compreendendo a Doença de Chron "Haz eso, haz aquello, mas yo estoy cayendo...": comprendiendo la enfermedad de Chron "Do this, do that, but I'm falling down...": understanding Chron's disease

    Directory of Open Access Journals (Sweden)

    Andrea Castelli

    2007-03-01

    Full Text Available Buscando compreender o significado e o impacto da doença de Chron na vida de seu portador, desenvolvemos este estudo, de natureza qualitativa, optando pela História Oral de Vida como referencial metodológico, tendo como base filosófica a corrente monista, advinda de Hipócrates, em que a prática médica tem por objeto a pessoa doente em sua totalidade, levando em conta seu temperamento e a sua história. A terapêutica deve restabelecer a harmonia da pessoa com seu ambiente e consigo mesma , trata-se de uma medicina integradora e dinâmica, que corresponde aos primórdios da medicina psicossomática. O estudo da doença de Chron, por meio da compreensão psicossomática, permitiu que analisássemos os sintomas, não como corpos estranhos a serem erradicados, mas como mensageiros de um apelo a ser compreendido. Por intermédio deles, pode ser resgatada a história de um indivíduo que, se conscientemente vivida e analisada, permite o desenvolvimento até níveis mais evoluídos de entendimento.Buscando comprender el significado y el impacto de la Enfermedad de Chron en la vida de su portador, desarrollamos este estudio, de naturaleza cualitativa, optando por la Historia Oral de Vida como referencial metodológico, y teniendo como base filosófica la corriente monista, advenida de Hipócrates, donde la práctica médica tiene por objeto a la persona enferma en su totalidad, teniendo en cuenta su temperamento y su historia. La terapéutica debe restablecer la armonía de la persona con su ambiente y consigo misma y se trata de una medicina integradora y dinámica, que corresponde a los inicios de la medicina psicosomática. El Estudio de la enfermedad de Chron, por medio de la comprensión psicosomática, permitió que analizásemos los síntomas, no como cuerpos extraños a ser erradicados, mas como mensajeros de un apelo a ser comprendido. Por intermedio de ellos, puede ser rescatada la historia de un individuo que, si conscientemente vivida

  11. Fluorine speciation analysis using reverse phase liquid chromatography coupled off-line to continuum source molecular absorption spectrometry (CS-MAS): identification and quantification of novel fluorinated organic compounds in environmental and biological samples.

    Science.gov (United States)

    Qin, Zhiwei; McNee, David; Gleisner, Heike; Raab, Andrea; Kyeremeh, Kwaku; Jaspars, Marcel; Krupp, Eva; Deng, Hai; Feldmann, Jörg

    2012-07-17

    Driven by increasing demand for the monitoring of industrial perfluorinated compounds (PFCs), the identification of novel fluorine containing compounds (FOCs) and the tracking of organofluorine drugs and their degradation products, there is a clear need for sensitive, fluorine-specific detection of unknown FOCs. Here we report the first ever direct fluorine-specific (speciation) method; capable of individually detecting untargeted FOCs in environmental and biological samples through the application of continuum source molecular absorption spectrometry (CS-MAS) using a commercial CS-AAS. Two model FOCs (2,4,6, trifluorobenzoic acid (TFBA) and 5-fluoroindol-5-carboxylic acid (FICA)) were used, achieving fluorine-specific detection across a range of 0.1 to 300 ng/mL fluorine, corresponding to a limit of detection of 4 pg F and 5.26 nM for both compounds. Both TFBA and FICA showed a similar response to CS-MAS detection, potentially enabling the quantification of fluorine content in novel FOCs without having molecular standards available. This paper also reports the use of reverse-phase high performance liquid chromatography (RP-HPLC) coupled off-line with CS-MAS for the identification of single organofluorines in a mixture of FOCs via fraction collection. The linear range of both FOCs was determined to be from 1 to 500 ng/mL. The limits of detection of those species were just above 1 ng/mL (100 pg) and can therefore compete with targeted analytical methods such as ESI-MS. Finally, as a proof of principle the analysis of a fluoride-containing groundwater sample from Ghana demonstrated that this method can be used in the detection of novel FOCs, with identification achieved through parallel ESI-MS. Coupled HPLC-CS-MAS/ESI-MS is the first analytical methodology capable of selectively detecting and identifying novel FOCs, making possible the quantification of all fluorine containing compounds in one sample. This is the necessary analytical requirement to perform

  12. 1H- 1H double-quantum CRAMPS NMR at very-fast MAS ( νR = 35 kHz): A resolution enhancement method to probe 1H- 1H proximities in solids

    Science.gov (United States)

    Mafra, Luís; Gomes, José R. B.; Trébosc, Julien; Rocha, João; Amoureux, Jean-Paul

    2009-01-01

    A High-resolution two-dimensional (2D) 1H double-quantum (DQ) homonuclear recoupling experiments, combined with smooth amplitude-modulation (SAM) homonuclear decoupling is presented. The experiment affords highly resolved and clean 1H DQ-SQ 2D spectra at very-fast MAS rates ( νR = 35 kHz). The method is well suited to probe 1H- 1H distances in powdered solids and demonstrations are applied on a NaH 2PO 4 powdered sample, an inorganic compound having hydrogen bonding networks.

  13. Tūrisma aģentūru "Faritour", "Amber Way" un "City Tour" reklāmas aktivitāšu efektivitāte 2008. gada pirmajā pusē

    OpenAIRE

    Morāns, Jānis

    2008-01-01

    Tūrisma mārketings Latvijā vēl ir tikai attīstības stadijā, tāpat kā pati tūrisma industrija. Bet uzņēmumiem, kam mērķa auditorija ir izkaisīta (tūrisma kompāniju gadījumā – ceļotāji nāk no visas pasaules) ir rūpīgi jāizvēlas ceļi, pa kuriem pie sava primārā patērētāj nokļūt. Darba nosaukums ir „Tūrisma aģentūru „Faritour”, „Amber Way” un „City Tour” reklāmas aktivitāšu salīdzinājums 2008. gada pirmajā pusē”. Darba hipotēze ir: tūrisma aģentūru „Faritour”, „Amber Way” un „City Tour” reklāmas ...

  14. Tautas partijas reklāmas un sabiedrisko attiecību kampaņas pirms 7. un 9. Saeimas vēlēšanām

    OpenAIRE

    Velika, Anna

    2007-01-01

    Tautas partija tika nodibināta 1998.gada maijā, īsi pirms 7.Saeimas vēlēšanām. Pateicoties harizmātiskajam līderim A.Šķēlem, masīvai reklāmas un sabiedrisko attiecību kampaņai, kā arī tautas uzticībai un cerībām jaunā partija gūst uzvaru vēlēšanās. Taču uzmanību piesaista fakts, ka šī partija, kas ir neraksturīgi pašreizējai Latvijas politiskajai skatuvei, spēj iekarot stabilu vietu gan valdībā, gan pašvaldībās, un ar profesionālu kampaņu palīdzību gūt panākumus arī divās nākamajās Saeimas vē...

  15. X ve Y Kuşağı: Hemşirelerin Meslek Dayanışması İle İş Doyumu Arasındaki İlişki

    OpenAIRE

    KARASU, Fatma; AYLAZ, Rukuye

    2017-01-01

    Amaç:Bu araştırma, X ve Y kuşağındaki hemşirelerin meslek dayanışması ile iş doyumuarasındaki ilişkisini belirlemek amacıyla yapılmıştır. Gereç ve Yöntem: Kesitsel nitelikteki araştırmanın evrenini devlethastanesinde çalışan hemşireler oluşturmuş, örneklem seçimine gidilmeyerekevrenin tamamı örnekleme dahil edilmiş ve 01.02.2017-01.03.2017 tarihleriarasında çalışmayı kabul eden toplamda 145 hemşireye ulaşılmıştır. Veri toplamaformunda, hemşirelerin sosyo-demografik özellikleri, Hemşirelerde M...

  16. David Durand-Guédy. Where did the Saljūqs live? A case study based on the reign of sultan Masʻūd b. Muḥammad (1134-1152)

    OpenAIRE

    Paul, Jürgen

    2017-01-01

    This can be read as a case study of “Ruling from the Outside” (see above, R4-1N4-6), and even if this text was published earlier, it certainly was written later than the more general one. The framework, including the three levels of analysis, is the same as in the previous article. Sulṭān Masʻūd b. Muḥammad b. Malikšāh (1134-52), the object of the case study, is presented as an itinerant king. Durand-Guédy’s study of this itinerant king – and his itineraries – therefore is the earliest such ...

  17. Virālo video izmantošana "airBaltic" reklāmas kampaņās. "Elves on plane", "airBaltic #flightmode" un "airBaltic lidojošais pārsteigums" gadījumi

    OpenAIRE

    Kalniņa, Mārīte

    2016-01-01

    Bakalaura darba “Virālo video izmantošana airBaltic reklāmas kampaņās. “Elves on plane”, “airBaltic #flightmode” un “airBaltic lidojošais pārsteigums” gadījumi” mērķis ir noskaidrot patērētāju un reklāmas aģentūras “CUBE” viedokļus par “airBaltic” veidotajiem virālajiem reklāmas video, attieksmi par reklāmas ievietošanu internetā, virālo video popularitāti un tendencēm Latvijā. Darba teorētisko daļu veido nodaļas par mārketingu, reklāmu, reklāmas kampaņām, partizāna mārketingu, jaunajiem med...

  18. İki "Kişilik" Düello Anayurdu; Anne Kız Çatışması Üzerine Bir İnceleme

    Directory of Open Access Journals (Sweden)

    Afif ATAMAN

    2017-10-01

    Full Text Available Sinema tarihi başlangıcından itibaren belli başlı dramatik anlatı temsillerini içerir. Aristo'nun Poetika'sından temellenen bu dramatik anlatılarda erkek özne konumunda ele alınır ve kadın karakter temsilleri ya erkeğin gözünden ya da erkeğin etkisinde şekillenir. Erkeğin konumlanışı aynı zamanda kadının da yaşam alanını belirler. Bu çerçeveden bakıldığında dünya sinemasındaki örneklerine benzer olarak genelde Türk Sineması tarihi, özelde ise yakın dönem Türk Sineması örnekleri çoğunlukla erkek hikâyelerine yaslanır. Dönemdaşlarının aksine Senem Tüzen'in Anayurdu adlı filmi bir yandan yaygın taşra anlatılarından farklı bir anlatımla anayurduna dönen bir kadının hikâyesini anlattığı, diğer yandan anne kız çatışmasına yer verdiği için bu çalışma kapsamında incelemeye değer bulunmuştur. Bu yaklaşımdan hareketle filmin anlatısına temel oluşturan anne-kız çatışması Carl Gustav Jung'un arketipleri çerçevesinde betimsel bir analizle incelenmektedir. Bu inceleme kapsamında çalışmanın ilk bölümünde Carl Gustav Jung'un arketiplerine ilişkin kavramsal yaklaşımına ilişkin literatüre yer verilmektedir. Çalışmanın ikinci bölümünde ise filmin hikâyesinden hareketle anne-kız çatışması Jung ve dolayısıyla arketiplerle ilişkileri çerçevesinde ortaya konulmaya çalışılmaktadır.

  19. Zastosowanie cieploprzewodzqcych mas klejowych w odlewnictwie

    Directory of Open Access Journals (Sweden)

    Z. Mirski

    2008-03-01

    Full Text Available Klcjc oparte na Swicy rnetaksylowej zaliczane sq do materirhbw nicprzewodqcych. Przcz nnpclnicnic klcju 2-sklndnikowcgo AgonictF330 obcq f~i7~wq postaci proszko~vychn apclniaczy mctaIo~vychm otna uzyskd wtnSciwoSci cic~lopr;/cwod~~mcacs klcjo~ycli.M ntcriatyte mogq by6 rvy koszystanc do rcgencracji powicrzchnio~vych wad odiewniczych do naprawy takich uszkodzcn jak pckni~cia, odpryskii wykruszcnia w odlewan ych clcmentach maszyn. Cieptoprtewodqcc masy kIcjorvc sq wykorzys~ywancd o hudowy prototypow~ychform odlcwniczych np, do poliuretanbw, stop6w niskotopliwych i w tcchnoIogiach rapid prototyping. Pominry przcwodnofci cicplncj lnnsklejqcych wykonano przy utyciu aparatu Pocnsgena, w tcmpcratunch: 30. 100 i 150 'C. Wstqpnc pon~iary wsp6lczynnikn przcicodnokicicplncj dla utwardzonych ktcjow wykazaly wartoit 1 = 0,2 W1m.K.W celu uzyskmin wlakiwoSci cicplopnc~vod~~cymcahs klcjoych (12 0.6W1rn.K I] tcprotmdmno do nich naptnincze w postaci proszk6w Vc i AI. Zachowujqc jcszczc wtaSci~voCcik lcjqcc micsmniny kl ju z ~iapclniacczamimetaloyni[ udalo sic wprowadzit 58% obi, proszk6w. Dzicki tcmu dla masy klcjowcj z nnpclniaczcn~n Iulninioivym udalo sic uqsknf itarioSCvs$lcqnnika pi-zcvdnoSci cicplncj 1, = 1,15 W/tn.K, w tempmturrr: otoczcnia 30 "C.

  20. Violencia contra las mujeres y alguien mas...

    OpenAIRE

    Piatti, Mª de Lujan

    2013-01-01

    La violencia contra las mujeres es una clara vulneración a sus derechos humanos. Es una violencia ejercida contra ellas por el solo hecho de ser mujeres; no se trata de casos aislados, sino que constituye un fenómeno social, presente en la sociedad actual sin distinción de razas, lugar geográfico, nivel cultural, religión, sistema político o económico. Investigar sobre “La violencia contra las mujeres y alguien más…”, desde una mirada multidisciplinar, significa bucear en las profundidades de...

  1. EAD sim, mas com qual biblioteca?

    Directory of Open Access Journals (Sweden)

    Solange Puntel Mostafa

    2003-07-01

    Full Text Available Discute a importância da biblioteca virtual para o ensino a distância de qualquer curso; para tal o bibliotecário deve ser elemento indispensável na equipe de EAD uma vez que ele conhece as fontes e as formas de organização da informação, o que lhe possibilita atuar inclusive como tutor. Recomenda-se a intervenção do bibliotecário já na fase de planejamento do curso de tal forma que a biblioteca resultante seja um produto/processo tão importante quanto os demais componentes curriculares e customizada ao curso em questão. Destaca a gestão da informação nos sites educacionais, essa outra modalidade de EAD na formação continuada de professores.

  2. MAS NMR study of the photoreceptor phytochrome

    NARCIS (Netherlands)

    Rohmer, Thierry

    2009-01-01

    Plants, algae and bacteria respond to light in various manners. The effect of light on the growth of plants is called photomorphogenesis and is regulated by the photoreceptor protein named phytochrome. Phytochrome is formed in the dark in its inactive red-absorbing (Pr) state and transformed upon

  3. Participar é preciso!: Mas de que maneira?

    Directory of Open Access Journals (Sweden)

    Donadone Julio César

    2001-01-01

    Full Text Available Este artigo investiga as flexões semânticas do significado hegemonicamente atribuído ao termo "participação" no contexto organizacional e trabalhista do Brasil dos últimos trinta anos, a partir de suas expressões na imprensa, particularmente a de negócios e a voltada para temas trabalhistas, e também, com menor grau de cobertura, em boletins sindicais e material de consultoria empresarial. O texto procura evidenciar a existência de um intenso processo de luta simbólica pela definição do conceito que reflete, ainda que de maneira não biunívoca, as diversas fases e vicissitudes por que passou o movimento operário e os embates internos ao espaço empresarial brasileiro no período, constituindo-se em uma excelente porta de entrada para uma análise do chamado "campo do poder" na sociedade brasileira. Este artigo historia o processo, tentando periodizar as fases da luta simbólica e extrair um mapa das mudanças de sentido observadas em relação ao conceito de "participação", insistindo sempre na dinâmica social que explica as transformações e a polissemia.

  4. Using THOMAS for Service Oriented Open MAS

    Science.gov (United States)

    Julian, V.; Rebollo, M.; Argente, E.; Botti, V.; Carrascosa, C.; Giret, A.

    Recent technological advances in open systems have imposed new needs on multi-agent systems. Nowadays, open systems require open autonomous scenarios in which heterogeneous entities (agents or services) interact to fulfill the system goals. This impose the need for open architectures and computational models for large-scale open multi-agent systems based on service-oriented approaches. THOMAS is a new architecture specifically addressed for the design of virtual organizations for open systems. In this paper we present a case study that exemplifies the usage of THOMAS for implementing a management system of a travel agency.

  5. Comparison of the thermal gain of the more commonly roofing systems used in Mexico`s social dwellings; Comparacion de la ganancia termica de los sistemas de techumbre mas comunmente utilizados en la vivienda social en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, Alfredo [Division de Estudios de Posgrado de la Facultad de Arquitectura UNAM, Mexico, D. F. (Mexico); Morillon, David [Comision Nacional para el Ahorro de Energia (CONAE), Mexico, D. F. (Mexico)

    1996-12-31

    Under the frame of discussion of the Mexican Official Standard 008 (Integral Energy Efficiency in non-residential Buildings), and with the purpose of assessing its feasibility and possible extension to residential buildings, this paper, whose objective is to evaluate the roofing systems (opaque) more commonly utilized on the social dwellings in Mexico, is presented. To perform this evaluation the heat gains by conduction through the roofing in different cities were obtained. Later on these heat gains were compared against the energy consumption that would produce its removal in each one of the cases. Finally, thermal resistance values (R) that allow, in significant form diminishing such gains, are presented, producing in consequence, a thermally efficient building. [Espanol] Dentro del marco de discusion de la Norma Oficial Mexicana 008 (Eficiencia energetica integral en edificios no residenciales), y con el fin de evaluar su factibilidad y posible extension hacia las edificaciones residenciales, se presenta este trabajo que tiene como objetivo la evaluacion de los sistemas de techumbre (opacos) mas comunmente utilizados dentro de la vivienda social en Mexico. Para realizar esta evaluacion se obtuvieron las ganancias por conduccion a traves del techo para distintas ciudades. Posteriormente, se compararon dichas ganancias contra el consumo de energia que produciria la remocion de las mismas en cada uno de los casos. Finalmente, se proponen valores de Resistencia Termica (R) que permitan disminuir de manera importante dichas ganancias teniendo, en consecuencia, una edificacion energeticamente eficiente.

  6. In situ solid state 11B MAS-NMR studies of the thermal decomposition of ammonia borane: mechanistic studies of the hydrogen release pathways from a solid state hydrogen storage material.

    Science.gov (United States)

    Stowe, Ashley C; Shaw, Wendy J; Linehan, John C; Schmid, Benjamin; Autrey, Tom

    2007-04-21

    The mechanism of hydrogen release from solid state ammonia borane (AB) has been investigated via in situ solid state (11)B and (11)B{(1)H} MAS-NMR techniques in external fields of 7.1 T and 18.8 T at a decomposition temperature of 88 degrees C, well below the reported melting point. The decomposition of AB is well described by an induction, nucleation and growth mechanistic pathway. During the induction period, little hydrogen is released from AB; however, a new species identified as a mobile phase of AB is observed in the (11)B NMR spectra. Subsequent to induction, at reaction times when hydrogen is initially being released, three additional species are observed: the diammoniate of diborane (DADB), [(NH(3))(2)BH(2)](+)[BH(4)](-), and two BH(2)N(2) species believed to be the linear (NH(3)BH(2)NH(2)BH(3)) and cyclic dimer (NH(2)BH(2))(2) of aminoborane. At longer reaction times the sharper features are replaced by broad, structureless peaks of a complex polymeric aminoborane (PAB) containing both BH(2)N(2) and BHN(3) species. The following mechanistic model for the induction, nucleation and growth for AB decomposition leading to formation of hydrogen is proposed: (i) an induction period that yields a mobile phase of AB caused by disruption of the dihydrogen bonds; (ii) nucleation that yields reactive DADB from the mobile AB; and (iii) growth that includes a bimolecular reaction between DADB and AB to release the stored hydrogen.

  7. Kimlik Politikasını Yeniden Düşünmek: Çağdaş Tanınma Tartışmasının Birikimi

    Directory of Open Access Journals (Sweden)

    Fırat MOLLAER

    2017-10-01

    Full Text Available Bu makale çağdaş tanınma teorisi tartışmalarını analiz etmektedir. Çağdaş tanınma tartışması Axel Honneth ve Nancy Fraser arasında geçen, kimlik ve tanınma mücadelesi hakkında yapılmış bir dizi tartışmanın genel adıdır. Tartışmanın ana fikri, Hegelci fenomenolojinin ‘tanınma mücadelesi’ gibi kavramlarının kimlik politikalarını anlamak için uygun bir felsefi temel sunup sunmadığı sorunuyla tanınma (recognition ve bölüşüm (redistribution gibi kategorilerin birbiriyle nasıl uzlaştırılacağıdır. Bu makalenin amacı, bu tartışmanın çözümlenmesi aracılığıyla kimlik politikaları ve tanınma mücadelesi sorunları üzerinde yeniden düşünülmesini sağlamaktır.

  8. Efektivitātes pētījums: Ceļu Satiksmes drošības direkcijas sociālās vides reklāmas

    OpenAIRE

    Vītola, Zanda

    2013-01-01

    Darba tēma ir „Efektivitātes pētījums: Ceļu Satiksmes drošības direkcijas sociālās vides reklāmas”. Pētījuma problēma – ik gadu palielinās upuru un negadījumu skaits uz Latvijas ceļiem, tāpēc ir svarīgi noskaidrot, cik efektīvas ir CSDD vides reklāmas, lai šo tendenci novērstu. Darba mērķis – noskaidrot sabiedrības viedokli un attieksmi pret CSDD vides reklāmām, atklājot, kā un vai reklāmu vēstījums ietekmē sabiedrību. Darbā izmantota Bārta teorija semiotiskās analīzes izpratnei, Kot...

  9. Cirrus Cloud Optical and Microphysical Property Retrievals from eMAS During SEAC4RS Using Bi-Spectral Reflectance Measurements Within the 1.88 micron Water Vapor Absorption Band

    Science.gov (United States)

    Meyer, K.; Platnick, S.; Arnold, G. T.; Holz, R. E.; Veglio, P.; Yorks, J.; Wang, C.

    2016-01-01

    Previous bi-spectral imager retrievals of cloud optical thickness (COT) and effective particle radius (CER) based on the Nakajima and King (1990) approach, such as those of the operational MODIS cloud optical property retrieval product (MOD06), have typically paired a non-absorbing visible or near-infrared wavelength, sensitive to COT, with an absorbing shortwave or midwave infrared wavelength sensitive to CER. However, in practice it is only necessary to select two spectral channels that exhibit a strong contrast in cloud particle absorption. Here it is shown, using eMAS observations obtained during NASAs SEAC4RS field campaign, that selecting two absorbing wavelength channels within the broader 1.88 micron water vapor absorption band, namely the 1.83 and 1.93 micron channels that have sufficient differences in ice crystal single scattering albedo, can yield COT and CER retrievals for thin to moderately thick single-layer cirrus that are reasonably consistent with other solar and IR imager-based and lidar-based retrievals. A distinct advantage of this channel selection for cirrus cloud retrievals is that the below cloud water vapor absorption minimizes the surface contribution to measured cloudy TOA reflectance, in particular compared to the solar window channels used in heritage retrievals such as MOD06. This reduces retrieval uncertainty resulting from errors in the surface reflectance assumption, as well as reduces the frequency of retrieval failures for thin cirrus clouds.

  10. İş-Aile Çatışması-Duygusal Emek İlişkisinde Lider Desteğinin Rolü: Eğitim Üzerine Bir Araştırma

    OpenAIRE

    DEMİRCAN, Pelin; TURUNÇ, Ömer

    2017-01-01

    Günümüz rekabet ortamında iş yaşamı ile aile yaşamı arasındaki etkileşimartmıştır. İşten aileye ve aileden işe yansıyan doğrudan ve dolaylı etkilerçalışanların tutum ve davranışında etkili olmaktadır. Duyguların iş yaşamındakiönemi giderek artmakta ve çalışan performansını etkilemektedir. Bu kapsamda;eğitim sektöründe iş-aile yaşam çatışması- duygusal emek ilişkisininbelirlenmesi ve bu ilişkide lider desteğinin aracılık rolünün olup olmadığınıbelirlenmesine yönelik ampirik bir çalışma yapılmı...

  11. Surface characteristics of the iron-oxyhydroxide layer formed during brick coatings by ESEM/EDS, {sup 23}Na and {sup 1}H MAS NMR, and ToF-SIMS

    Energy Technology Data Exchange (ETDEWEB)

    Allahdin, O. [Chaire Unesco « Sur la gestion de l' eau », Laboratoire Hydrosciences Lavoisier, Université de Bangui, Faculté des Sciences, B.P. 908 (Central African Republic); Wartel, M. [Université Lille1, Laboratoire LASIR (UMR CNRS 8516), Equipe Physico-chimie de l' Environnement, Bât. C8, 2" è" m" e étage, 59655 Villeneuve d' Ascq cedex (France); Mabingui, J. [Chaire Unesco « Sur la gestion de l' eau », Laboratoire Hydrosciences Lavoisier, Université de Bangui, Faculté des Sciences, B.P. 908 (Central African Republic); Revel, B. [Université Lille1, Service RMN, Bât. C4, 59655 Villeneuve d' Ascq cedex (France); Nuns, N. [Université Lille1, Institut Chevreul, 59655 Villeneuve d' Ascq cedex (France); Boughriet, A., E-mail: abdel.boughriet@univ-lille1.fr [Université Lille1, Laboratoire LASIR (UMR CNRS 8516), Equipe Physico-chimie de l' Environnement, Bât. C8, 2" è" m" e étage, 59655 Villeneuve d' Ascq cedex (France)

    2015-09-01

    Brick made locally by craftsmen in Bangui (Central African Republic) was modified first by HCl activation and second by iron-oxyhydroxide impregnation through the precipitation of ferric ions by NaOH at various fixed pH values (ranging from 3 to 13). The elemental analyses of synthesized compounds were performed using ICP-AES, and their surface chemistry/properties were investigated by environmental scanning electron microscopy (ESEM/EDS), {sup 1}H and {sup 23}Na MAS NMR spectroscopy, and time-of-flight secondary ion mass spectrometry (ToF-SIMS). The evidence of different {sup 23}Na chemical environments and the coexistence of Si and Al bound to ferrihydrite were made. The surface properties of this material which was found to be dependent upon synthesis pH, contributed to enhance metal uptake from water. - Highlights: • HCl-activated brick was coated at different Fe(III)-precipitation pH. • Surface properties were determined by ESEM, NMR and ToF-SIMS. • Al- and Si-bearing ferrihydrite and different Na environments were detected. • The pH used for modified-brick synthesis influenced metal uptake from water.

  12. Metabolic profiling of apples from different production systems before and after controlled atmosphere (CA) storage studied by 1H high resolution-magic angle spinning (HR-MAS) NMR.

    Science.gov (United States)

    Vermathen, Martina; Marzorati, Mattia; Diserens, Gaëlle; Baumgartner, Daniel; Good, Claudia; Gasser, Franz; Vermathen, Peter

    2017-10-15

    Determination of metabolic alterations in apples induced by such processes as different crop protection strategies or storage, are of interest to assess correlations with fruit quality or fruit disorders. Preliminary results proposed the metabolic discrimination of apples from organic (BIO), integrated (IP) and low-input (LI) production. To determine contributions of temporal metabolic developments and to define the type of metabolic changes during storage, 1 H high resolution-magic angle spinning (HR-MAS) NMR spectroscopy of apple pulp was performed before and after two time points of controlled atmosphere storage. Statistical analysis revealed similar metabolic changes over time for IP-, LI- and BIO-samples, mainly decreasing lipid and sucrose, and increasing fructose, glucose and acetaldehyde levels, which are potential contributors to fruit aroma. Across the production systems, BIO apples had consistently higher levels of fructose and monomeric phenolic compounds but lower levels of condensed polyphenols than LI and IP apples, while the remaining metabolites assimilated. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. İslam’da Orta Yol ve Medeniyetler Çatışması Teorisi (Karşılaştırmalı Bir İnceleme)

    OpenAIRE

    WĀDİ, Munshid Fāleh

    2018-01-01

    Bu çalışmada, medeniyetler çatışması nazariyesine karşın İslamın orta yolu hedeflediği şu doğrultuda ele alınmaktadır: Öncelikle bu çalışma, İslamın; tasavvur, sülûk ve hükümde orta yolu temsil ettiğini ortaya koyar. Zira İslam, dengeli ve vakaaya uygun bir görüşü benimser ve bu, milletler, ırklar ve mezheplerin beraber yaşamalarını sağlar. İkincisi, İslami hareketler ve fikrî doktrinler arasındaki çatışmayı ortadan kaldıracak ortak bir zeminin bulunmasını amaçlar. Üçüncüsü insanlığın maslaha...

  14. An evaluation of microwave-driven stannylation followed by in situ {sup 119}Sn MAS n.m.r. spectroscopy as a probe for hydroxyl functionality in medium-rank British coals and macerals

    Energy Technology Data Exchange (ETDEWEB)

    Manak, H.; Monsef-Mirzai, P.; McWhinnie, W.R.; Hamor, T.A. [Aston University, Birmingham (United Kingdom). Dept. of Chemical Engineering and Applied Chemistry

    1997-07-01

    The paper describes the derivatization of hydroxyl groups in coals and coal macerals by stannylation. Stannylation of a range of phenolic compounds with Me{sub 3}SnCl, Bu{sub 3}SnCl and (Bu{sub 3}Sn){sub 2}O (TMTO) was carried out under both microwave-driven and conventional conditions. The degree of Stannylation was influenced by the steric environment of the OH group, implying that stannylation in comparison with, say trimethylsilylation of OH groups could help to map the steric environments of phenolic groups in coals. Good maceral separations of Creswell coal and acceptable separation of Cottonwood coal were achieved. The whole coals and the macerals were stannylated with TBTO under microwave-enhanced conditions and the products were examined by {sup 119}Sn MAS n.m.r. and X-ray photoelectron spectroscopy. The reaction was confined to surface regions. Differences were found in the behaviour of the macerals. The crystal and molecular structures of the trimethylstannyl derivative of 2,6-diphenylphenol were determined, to establish the validity of the claim to have stannylated model compounds. Molecular parameters were compared with related systems. 18 refs., 3 figs., 5 tabs.

  15. Mobilā reklāma kā mobilo priekšapmaksas sarunu karšu reklāmas komunikācijas instruments: Y paaudzes radītās iespējas

    OpenAIRE

    Daudze, Anita

    2009-01-01

    Bakalaura darba temats ir „Mobilā reklāma kā mobilo priekšapmaksas sarunu karšu reklāmas komunikācijas instruments: Y paaudzes radītās iespējas”. Pētījuma problēma ir mobilās reklāmas piemērotība komunikācijai ar Y paaudzes pārstāvjiem – mobilo priekšapmaksas sarunu karšu lietotājiem. Darba teorētiskais pamatojums balstīts uz Y paaudzes jēdziena izpratni, mobilā telefona kā reklāmas komunikācijas kanāla aplūkošanu, kā arī mobilā mārketinga un reklāmas pamatprincipu izklāstu. Darbā izman...

  16. 2;0-4;0 Yaş Aralığındaki Çocuklar Tarafından Üretilen Rica Sözceleri Üzerine Bir Analiz Çalışması

    Directory of Open Access Journals (Sweden)

    N. Tayyibe Eken

    2014-10-01

    Full Text Available Çocukların iletişim amaçlı ilk üretimleri, gereksinimlerini aktardıkları ricalardır. Ricaların iletişimsel rollerden etkilenerek farklı biçimlerde üretilebildiği görülmektedir. Bu araştırmada; çocukların farklı etkileşimlerdeki rollerinin, rica sözcelerine yansıması konu edilmiştir. Çalışmanın amacı 2;0-4;0 yaş aralığındaki çocukların farklı bağlamlarda, ne tür rica sözceleri ürettiklerine ilişkin saptamalar yapılmasıdır. Katılımcı gözlem ve içerik çözümlemesi yöntemlerinin kullanıldığı çalışmanın örneklem grubu küme örnekleme tekniğiyle oluşturulmuştur. Edinim çalışmalarında 6 aylık dönemlerin önem taşıdığı sayıltısından hareketle her altı aylık dönem için 8’er çocuk seçilmiştir. Yapılandırılmamış alan çalışması niteliğinde toplanan doğal konuşma verisinin çözümlenmesinde kategori ve frekans analizleri kullanılmıştır. Çalışmanın kuramsal temelini oluşturan Dore (1978 ricaları; bilgi, eylem ve izin/onay isteme biçiminde üç alt kategoriye ayırmıştır. Çalışmanın temel bulgularına göre ricaların kullanım hiyerarşisi; eylem isteme>izin/onay isteme>bilgi isteme biçimindedir. Ricaların genellikle emir, bildirim ve soru biçimlerinde aktarıldığı; eylem istemede emir biçiminin, bilgi istemede ne/kim sorularının, izin/onay istemede ise evet/hayır sorularının kullanıldığı, dinleyici-konuşucu rollerinin ve yaşın rica üretimi açısından değişken değeri taşıdığı gözlenmiştir.

  17. Türk Fermente Sucuğunun Olgunlaşması Sırasında Tyramin Düzeyindeki Değişiklikler (İngilizce

    Directory of Open Access Journals (Sweden)

    Suzan Yalçın

    2015-02-01

    Full Text Available Bu araştırma, Türk fermente sucuğunun olgunlaşması süresince tyramin düzeylerindeki değişiklikleri incelemek ve sucukların tyramin düzeyleri ile bazı parametreleri (pH değeri, kuru madde miktarı arasındaki ilişkiyi belirlemek amacıyla yapıldı. Sucuk numuneleri olgunlaşmaları süresince pH, kuru madde ve tyramin düzeyleri yönünden incelendi. Tyramin miktarı olgunlaşmanın ilk üç günü süresince önemli bir artış göstererek altıncı günde maksimum düzeye ulaştı. Daha sonraki günlerde, tyramin düzeyinde azalma gözlendi. Sucukların pH ve tyramin düzeyi arasında önemli negatif bir korelasyon (r= -0.80, p<0.05 bulundu. Düşük düzeyde tyramin içeren sucukların elde edilmesinde pH değerinin çok önemli olabileceği kanısına varıldı.

  18. Plantando, colhendo, vendendo, mas não comendo: práticas alimentares e de trabalho associadas à obesidade em agricultores familiares do Bonfim, Petrópolis, RJ

    Directory of Open Access Journals (Sweden)

    Ana Eliza Port Lourenço

    Full Text Available OBJETIVO: verificar a prevalência de obesidade entre adultos das 86 famílias agricultoras de um bairro de Petrópolis, RJ, e analisar seus determinantes socioculturais. MÉTODOS: estudo quantitativo e qualitativo sobre nutrição, práticas alimentares e de trabalho realizado em 2008. Dados antropométricos foram coletados por inquérito nutricional domiciliar e o material qualitativo por observação participante e entrevistas. RESULTADOS: a prevalência de obesidade foi baixa (9,3% entre os homens, mas bastante elevada entre as mulheres (29,9%. A prática agrícola local implica em atividade física leve para mulheres e intensa para homens. Essa diferença não é acompanhada na dieta, semelhante para homens e mulheres, com predomínio de alimentos de alto valor calórico. A produção familiar objetiva essencialmente a venda. A agricultura mercantil e a decorrente especialização dos cultivos favorecem comprar alimentos no mercado em vez de produzir para autoconsumo. CONCLUSÃO: os aspectos socioculturais e ocupacionais estudados podem ter contribuído para elevar a prevalência de obesidade nas mulheres e podem ser úteis no estudo de outros grupos com características semelhantes. Esta pesquisa ratifica a importância de estudar a obesidade em nível local, integrando abordagens quantitativas e qualitativas para identificar possíveis limitações e portas de entrada para ações de intervenção localmente relevantes.

  19. Madde-Ruh Çatışmasından Simeranya’ya Kaçış: Yalnızız Escape to Simeranya from Item-Spirit Conflict : Yalnızız

    Directory of Open Access Journals (Sweden)

    Adem POLAT

    2012-09-01

    Full Text Available This article is a consideration of matter-soul conflict which has a close relationship with the thought dimension established upon historical, sociological and cultural ground in the novel of Yalnızız of Peyami Safa, who has a crucial place in the Turkish Novel in the Republic period. The conflict in question and the paradoxes ingrained in society, emerges besides moral corruption. More importantly, Yalnızız is a novel which has the motivation to produce remedial solutions within aplan like Simeranya. In this respect, an utopian fiction, Simeranyaphenomenon’s effect on the character Samim, displays the intellectualground upon which matter-soul conflict built. These grounds do notonly include the ideal of the world the artist yearns for, but also theydisclose the factual values that will be conveyed as a message throughthe confrontation of matter-soul in the center of the novel. Inconsequence, even though it is beyond reality like Simeranya, inYalnızız novel, the crucial parameters for Turkish thought areconsidered on the agenda by Peyami Safa, as a solution suggestion tothe enduringly growing phenomena and which are carried towardstoday since our Westernization history.In other words, Simeranya is a sheltering territory from theanxiety that are felt due the social and actual realm. If it must be told inthe words of the KORA thematic system, Simeranya, is the place whichgathers dialectical affirmation of the conflicting values in thephenomenal realm of the ideal values. This work aims to scrutinize theintellectual grounds that are describable through the theme of mattersoulconfrontation in question. Bu makale Cumhuriyet devri Türk romanında önemli bir yere sahip olan Peyami Safa’nın Yalnızız romanında yer alan tarihsel, sosyolojik ve kültürel zemine bağlı olarak ortaya çıkmış olan düşünce boyutuyla yakından ilişki kuran madde-ruh çatışmasının roman üzerindeki bir değerlendirmesidir. Söz konusu

  20. Adiposidade corporal, mas não resistência insulínica, associa-se ao polimorfismo -675 4G/5G no gene PAI-1 em uma amostra de crianças mexicanas

    Directory of Open Access Journals (Sweden)

    Ulises de la Cruz-Mosso

    2013-10-01

    Full Text Available OBJETIVO: Elaboramos este estudo para avaliar se o polimorfismo -675 4G/5G no gene inibidor 1 do ativador do plasminogênio se associa à obesidade e à resistência insulínica em crianças mexicanas. MÉTODOS: Foi realizado um estudo transversal em 174 crianças, 89 delas com peso normal e 85 obesas, variando sua idade de 6 a 13 anos. Todas as crianças eram do estado de Guerrero e foram recrutadas de três escolas primárias na cidade de Chilpancingo, México. Os níveis de insulina foram determinados por prova imunoenzimática. Foi usado o modelo de avaliação da homeostase para determinar resistência insulínica. O polimorfismo -675 4G/5G no gene PAI-1 foi analisado pelo método reação de polimerase em cadeia-polimorfismo no comprimento dos fragmentos de restrição. RESULTADOS: A prevalência de resistência insulínica no grupo obeso foi mais alta (49,41% do que no grupo com peso normal (16,85%. O polimorfismo 4G/5G do PAI-1 foi encontrado em equilíbrio de Hardy Weinberg. O genótipo 4G/5G contribuiu para um aumento significativo da relação cintura-quadril (β = 0,02, p = 0,006, da circunferência da cintura (β = 4,42, p = 0,009 e da espessura da prega subescapular (β = 1,79, p = 0,04, mas não se relacionou com a resistência insulínica. CONCLUSÃO: O genótipo -675 4G/5G do gene PAI-1 se associou a aumento da adiposidade corporal em crianças mexicanas.

  1. The silicalite(MFI)/p-nitroaniline system. I. Location of the sorbed molecules at medium and high pore-fillings. A study by X-ray powder diffraction, 29Si mas NMR and energy minimization calculations

    Science.gov (United States)

    Mentzen, B. F.; Lefèbvre, F.

    1998-05-01

    Structural investigation of the silicalite(MFI)/np-nitroaniline system by X-ray powder diffraction, establishes the existence of two single phased host/guest complexes corresponding to n=4 and 8 at medium and high pore-fillings respectively. Predictive studies by molecular mechanics simulations indicate that the pNAN molecules are located at the channel-intersections (for n=4) or in the elliptic channel-sections of the MFI topology (for n=8). 29Si solid-state mas NMR measurements show that the actual MFI framework symmetry of the silicalite.4pNAN complex is acentric Pn21a. Interpretation of the XRD pattern corresponding to the saturated silicalite. 8pNAN complex by Rietveld type structure refinements shows that two independent pNAN molecules are located on sites II (zig-zag channel sections) and sites III (straight channel sections). The van der Waals type interactions between the sorbed molecules take place at the channel-intersections (sites I). These sites are not occupied by extra-framework species. This is in agreement with the commensurability criterion already observed in several MFI/sorbate systems. Une étude structurale du système silicalite(MFI)/np-nitroaniline (pNAN) par diffraction des rayons X sur poudres, dans le domaine des concentrations 4des canaux (pour n=4) ou dans les sections elliptiques des canaux de la charpente zéolithique MFI (pour n=8). L'étude structurale du complexe silicalite.4pNAN, par diffraction X et RMN à l'état solide du noyau 29Si, établit que le groupe d'espace est non-centrosymétrique Pn21a. Dans le complexe saturé silicalite.8pNAN, deux espèces pNAN indépendantes sont adsorbées sur les sites II (canaux en zig-zag) et III (canaux droits). En accord avec le critère de commensurabilité, les sites I (intersections des canaux) ne contiennent pas d'espèces extra-charpente.

  2. Klientu attiecību pārvaldes sistēmas ieviešana IT uzņēmumā un pielāgošana tā biznesa vajadzībām

    OpenAIRE

    Šmitenbergs, Oskars

    2006-01-01

    Bakalaura darbs „Klientu attiecību pārvaldes sistēmas ieviešana IT uzņēmumā un pielāgošana tā biznesa vajadzībām” ir sistēmas Microsoft Dynamics™ CRM 3.0 ieviešanas procesa apraksts IT uzņēmumā SIA „UNITREE”. Darbs sniedz ieskatu sistēmas ieviešanas nepieciešamības cēloņos vidēja lieluma un lielos uzņēmumos. Kā viena no problēmu cēloņu novēršanas iespējām tiek piedāvāta Microsoft Dynamics™ CRM 3.0 ieviešana uzņēmumā, tāpēc darbā galvenokārt tiek apskatīta biznesa pārvaldības iespējas, izmanto...

  3. “Meninas não desenham carros... mas têm meninas que desenham”: culturas infantis, relações de gênero e histórias em quadrinhos

    Directory of Open Access Journals (Sweden)

    Marta Regina Paulo da Silva

    2016-04-01

    Full Text Available Este artigo discute a produção das culturas infantis a partir das experiências de meninos e meninas, de 3 a 5 anos de idade, com a linguagem das histórias em quadrinhos (HQs, tendo como foco as relações de gênero. Reconhece as HQs como uma das produções midiáticas que interfere nos modos de viver das crianças, muitas vezes reforçando estereótipos fundados nas diferenças sexuais. Assim, em uma interlocução com a filosofia, sociologia, sociologia da infância, pedagogia da infância e arte, problematiza como as crianças se apropriam dos quadrinhos, o que deles reproduzem, inventam ou reinventam. Trata-se de um estudo de caso realizado em uma pré-escola municipal localizada na região do Grande ABC Paulista, que teve como procedimentos metodológicos: a observação e registro de campo, os relatos orais das crianças, a análise dos documentos oficiais da Rede Municipal de Educação e da pré-escola, entrevista com quadrinhista e a análise das HQs produzidas pelas crianças. Defende que meninos e meninas participam de maneira ativa na sociedade da qual fazem parte, portanto, não só reproduzem a cultura do mundo adulto, mas ao se apropriarem coletiva e criativamente desta produzem as culturas infantis. Demonstra serem as HQs parte da cultura material da infância, que se constituem em suportes para aspectos simbólicos das culturas infantis, que as crianças compartilham entre si e com os adultos e as adultas, onde se observam padrões e valores identitários sendo negociados; isso revela que elas não só reproduzem estereótipos da cultura heteronormativa, mas transgridem as fronteiras de gênero. Nesse sentido, aponta para o desafio de trazer as crianças para o debate acerca da relação “infâncias, mídia e gênero”, na perspectiva de (reconhecer como elas fruem, produzem e vão além das imagens midiáticas.   “Girls don´t draw cars… but there are girls who do it”: child cultures, gender and comics

  4. İşbirliği İle Bireyselleştirilmiş Eğitim Programı Geliştirme Süreci: Durum Çalışması

    Directory of Open Access Journals (Sweden)

    Sezgin Vuran

    2017-07-01

    Full Text Available Bu çalışmanın amacı Zihin Engelliler Öğretmenliği Programı öğretmen adaylarının Bireyselleştirilmiş Eğitim Programlarının Hazırlanması ve Öğretimin Bireyselleştirilmesi dersinde, işbirliği ile Bireyselleştirilmiş Eğitim Programları (BEP geliştirmeleri ve bir ekiple birlikte çalışma becerilerini kazanmaları sürecinin ve sonuçlarının betimlenmesidir. Çalışma nitel araştırma yöntemi olan durum çalışması olarak yürütülmüştür. Çalışmaya toplam 100 öğretmen adayı ve üç öğretim elemanı katılmıştır. Çalışmada veriler; katılımcı gözlem, saha notları, öğretmen adayı ödevleri, öğretmen adayı günlükleri ve öğretim elemanı görüşleri kullanılarak toplanmıştır. Toplanan veriler içerik analizi yapılarak analiz edilmiştir. Çalışmada uygulama sürecinde işbirliği ile öğretim ve öğrenme yaklaşımları benimsenmiştir. İşbirliği ile öğrenme yolu ile ekip üyelerinin BEP hazırlama becerilerin gelişmesinin yanı sıra BEP’in önemli gerekliliklerinden biri olan ekiple çalışma becerileri de gelişmiştir. Ayrıca dersin işbirliği ile öğretim yolu ile yürütülmesi öğretmen adaylarına işbirliği ile çalışmaya iyi bir model oluşturmuştur. Bu çalışma sonucunda öğretmen adayları hem bireysel hem grup olarak BEP hazırlama aşamalarını izleyerek özel gereksinimi olan bir öğrencinin gereksinimlerine uygun bir BEP hazırlamışlar ve öğretim uyarlamaları yapmışlardır. Ek olarak, işbirliği ile BEP hazırlama sürecinde öğretmen adaylarının birbirleriyle etkili bir iletişim kurdukları ve oldukça hevesli şekilde derse katıldıkları gözlenmiştir. Bu çalışmanın bulguları öğretmen adaylarının ileride yaşayabilecekleri zorluklarla baş etmeleri ve sürece hazırlanmaları için öğretmenlere yardımcı olacaktır. The purpose of this study is to reveal the process and the results of the development of an

  5. Small Hydropower in Latvia and Intellectualization of its Operating Systems / Par Mazo HIDROENERĢĒTIKU LATVIJĀ un TĀS Staciju VADĪBAS SISTĒMAS INTELEKTUALIZĀCIJU

    Science.gov (United States)

    Mahnitko, A.; Gerhards, J.; Linkevics, O.; Varfolomejeva, R.; Umbrasko, I.

    2013-12-01

    The authors estimate the potential for power generation from water resources of small and medium-sized rivers, which are abundant in Latvia. They propose the algorithm for optimal operation of a small-scale hydropower plant (SHPP) at the chosen optimality criterion in view of the plant's participation in the market. The choice of SHPP optimization algorithm is made based on two mathematical programming methods - dynamic and generalized reduced gradient ones. Approbation of the algorithm is illustrated by an example of optimized SHPP operation. Darbā analizētas tradicionālo un pieejamo vietējo atjaunojamo energoresursu - mazo un vidējo upju hidroresursa izmantošanas iespējas Latvijas enerģētikā. Tiek sniegts faktiskais materiāls šajā jautājumā, kas iegūts, balstoties uz oficiālos avotos publicētiem citu autoru iepriekš veiktajiem pētījumiem. Tiek atzīmēts, ka teritoriju, kas atrodas mazo upju tuvumā un nav ietvertas centralizētās elektroapgādes sistēmā, saimnieciskā apgūšana rada apstākļus patērētāju stimulēšanai izmantot autonomus vietējos energoresursus, ieskaitot hidroenerģiju, izmantojošas mazas jaudas energoiekārtas. Atjaunojamās enerģijas tehnoloģiju un iekārtu pastāvīga attīstība un pilnveidošanās veicinās mazo upju plūsmas izmantošanas elektroenerģijas ražošanas efektivitātes paaugstināšanos. Mūsdienu enerģētikas attīstības koncepcija, kas balstīta uz viedo tīklu (smart grids) izveidi, ļauj paaugstināt mazās hidroenerģētikas darbības efektivitāti, integrējot to elektroenerģētiskajā sistēmā. Mazo hidroelektrostaciju (MHES) darbības vadības sistēmas intelektualizācijas pamatā jābūt kompleksam algoritmam un programmām, kas ļauj tiešsaistes (online) režīmā nodrošināt izdevīgu MHES darbības grafiku (režīmu) maksimālā ienākuma gūšanai, balstoties uz zināmu elektroenerģijas cenas prognozi attiecīgajam laika periodam (diennaktij). MHES darbības optimiz

  6. Folikül Büyüklüğü ve Folikül Uyarıcı Hormon Konsantrasyonunun Sığır Oositlerinin İn Vitro Nükleer Olgunlaşması Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Uğur Şen

    2015-05-01

    Full Text Available Bu çalışma folikül büyüklüğü ve folikül uyarıcı hormon (FSH konsantrasyonunun sığır oositlerinin in vitro nükleer olgunlaşması üzerine etkisini araştırmak amacıyla yapılmıştır. Sığır ovaryumundaki (87 adet foliküller küçük (

  7. Reklāmas ietekme uz uzņēmuma tēla veidošanos integrētā mārketinga komunikācijās. Olimpiskā centra "Ventspils" piemērs

    OpenAIRE

    Boitmane, Līva

    2008-01-01

    Latvijā pēdējo gadu laikā tiek atvērti arvien jauni Olimpiskie centri, tādēļ bakalaura darba „Reklāmas ietekme uz uzņēmuma tēlu integrētā mārketinga komunikācijās. Olimpiskā centra „Ventspils” piemērs”, mērķis ir izpētīt, kā Olimpiskais centrs „Ventspils” veido savu uzņēmuma tēlu, vai strādājot pie pakalpojumu reklāmas izveides tiek mērķtiecīgi veidots Olimpiskā centra tēls jeb imidžs. Darbā sākotnēji tiek analizēta integrētā mārketinga komunikācijas teorija, aprakstīta viena no tā sastāv...

  8. Auge y Caída de la Masonería en México en el Siglo XIX. La Exclusión de la Mujer bajo la mirada del Discurso Masónico de Laureana Wright González

    OpenAIRE

    Martínez Moreno, Carlos Francisco

    2012-01-01

    La masonería femenina en México fue efímera en el siglo XIX, surgió con el apoyo de masones varones comprometidos con la educación de la mujer y su emancipación del dogma católico, que no lograron emanciparse de los dogmas masónicos incoherentes con el progreso que decían defender; que por presiones de la masonería internacional optaron por el conservadurismo de sus normas antes que perder el reconocimiento de la masonería regular, con lo que excluyeron a la mujer de la masonería. Female F...

  9. Un análisis institucional de la implicación del proceso de cambio de los SCG en la evolución de la eficiencia de las PYME An institutional analysis of the implication of the MAS change process for the evolution of SMSC efficiency

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Facin Lavarda

    2009-04-01

    Full Text Available El objetivo general de este trabajo es conocer la relación existente entre el proceso de cambio de un Sistema de Contabilidad de Gestión (SCG en las pequeñas y medianas empresas (PYME y el éxito que genera dicho cambio. El éxito del cambio del SCG se va a medir a través de dos indicadores. El primer indicador, el éxito interno, medirá la distancia que existe entre las expectativas (qué se esperaba de las nuevas técnicas de gestión implantadas y las realidades (qué son. El segundo indicador, el éxito externo, medirá la variación en el nivel de eficiencia relativa de la empresa dentro de su sector. La hipótesis básica de este estudio, plantea que el proceso de cambio puede explicar el nivel de éxito (interno-externo alcanzado en el cambio de un SCG. Para captar y analizar los datos, utilizaremos dos técnicas: el Análisis Envolvente de Datos (DEA y el método del Estudio de Caso (EDC. Los resultados de la investigación permitieron conocer los que factores influyeron, y por tanto explican el éxito de un cambio en los SCG de una PYME del sector de la madera y mueble de la Comunidad Valenciana, España, entre ellos: los conocimientos y habilidades de los agentes implicados en el cambio, la influencia de los expertos externos, la profesionalización de la gestión, los recursos informáticos, la formación interna en SCG, la confianza entre los agentes y la implicación de las personas. Además, hemos observado que los cambios producidos a lo largo de los años analizados influyeron positivamente en el nivel de eficiencia de la organización.This study's general objective is to get to know the relation between the change process of a Management Accounting System (MASO in small and medium-sized companies (SMSC and the success of this change. The success of the MAS change is measured by two indicators. The first, internal success, measures the distance between the expectations (what was expected about the new management techniques

  10. Ressenya a Alexandre Font Jaume, Gabriel Ensenyat Pujol, Àngela Martí Borràs, Mireia Mulet Mas, Josep Campillo Galmés (eds: Joan Baptista Binimelis: Sobre els vicis de les dones i el seu tarannà variable. Catàleg de dones especialment sàvies, Palma, Lleonard Muntaner, Editor (col·lecció L’Arjau, 36, 2014, 349 pp., ISBN: 978-84-16116-16-4

    Directory of Open Access Journals (Sweden)

    Joan-Antoni Mesquida Cantallops

    2014-12-01

    Full Text Available Review to Alexandre Font Jaume, GabrielEnsenyat Pujol, Àngela Martí Borràs, Mireia Mulet Mas, Josep Campillo Galmés (eds: Joan Baptista Binimelis: Sobre els vicis de les dones i el seu tarannà variable. Catàleg de dones especialment sàvies, Palma, Lleonard Muntaner, Editor (col·lecció L’Arjau, 36, 2014, 349 pp., ISBN: 978-84-16116-16-4

  11. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS

    Directory of Open Access Journals (Sweden)

    Deyan Zdravkov Neychev

    2016-08-01

    Full Text Available Abstract Objective: The objective of this study is to determine the change in IL-6 serum levels in patients undergoing preemptive analgesia and surgical removal of an impacted mandibular third molar. Study Design: This is a prospective, double-blind, placebo-controlled study in 80 patients who had an atypical extraction of an impacted mandibular third molar. Results: After surgical removal of impacted mandibular third molars, elevated levels of IL-6 in the early postoperative period were found, and the highest level was 14 pg/ml. Conclusion: Postoperative IL-6 levels rise regardless of the medication used for preemptive analgesia. In the group treated with nimesulide, a trend to reducing IL-6 levels was observed, but further study in a larger number of patients is needed.

  12. Nėščiųjų ir jaunų negimdžiusių moterų krūtų tūrio, kūno dydžio ir pasyviosios masės lyginamasis tyrimas

    Science.gov (United States)

    Drąsutis, Jonas; Barkus, Arūnas; Kairienė, Elena; Drąsutienė, Gražina; Norvilaitė, Kristina; Tutkuvienė, Janina

    2016-01-01

    Tikslas. Palyginti nėščiųjų ir jaunų negimdžiusių moterų kūno ir krūtų dydžio rodiklius. Medžiaga ir metodika. 2008–2009 m. (I tyrimas) ištirti 82 jaunų negimdžiusių devyniolikos metų amžiaus merginų krūtų ir kūno dydžio rodikliai, jie palyginti su 2013–2015 m. (II tyrimas) Vilniuje tirtų nėščiųjų (pirmuoju nėštumo trečdaliu) tais pačiais kūno stambumo ir krūtų parametrais – ūgiu, svoriu, įvairių kūno dalių apimtimis, odos klostėmis, pasyviąja kūno mase ir krūtų tūriu. Kūno dydžio rodikliams palyginti visos tiriamosios buvo skirstomos į grupes pagal krūtų dydį ir kūno stambumą (procentiliniu metodu). Nėščiosios suskirstytos į gimdančias pirmą kartą ir pakartotinai. Abiejuose tyrimuose naudota standartinė antropometrinė metodika. Krūties tūris apskaičiuotas pagal R. Kramerio ir G. Dexlerio (1981) formulę. Pasyviosios kūno masės (riebalinio audinio) kiekis procentais – pagal odos ir poodžio riebalines klostes naudojant W. E. Sirio (1961), J. H. Wilmorės ir A. R. Behnkės (1970) formules. Rezultatai, nustatyti visų parametrų aprašomosios statistikos, įvairovės ir pasiskirstymo rodikliais, apdoroti naudojant SPSS 22.0 programą. Skirtumai tarp tiriamųjų grupių vertinti pagal Stjudento t kriterijų. Pasirinktas patikimumo lygmuo p ir juosmens klubų indeksas. Nėščių moterų riebalinis audinys kaupėsi daugiau viršutinėje kūno dalyje, nors santykinė ir absoliuti pasyvioji kūno masė tarp grupių skyrėsi nereikšmingai. Lyginant pirmą kartą ir pakartotinai gimdančių su jaunų negimdžiusių moterų rodmenimis paaiškėjo, kad pakartotinai gimdančios moterys turėjo didesnį riebalinio audinio kiekį, o pirmąkart ir jaunų negimdžiusių merginų rodikliai reikšmingai nesiskyrė. Mažų, vidutinių ir didelių krūtų grupių nėščių moterų kūno dydžio rodikliai buvo didesni negu jaunų negimdžiusių merginų analogiški rodmenys. Liesų moterų kūno dyd

  13. Athlete Branding = Atlet Markalaşması

    OpenAIRE

    Van Schaik, Thomas

    2016-01-01

    Thomas van Schaik (@thomasvanschaik) Thomas van Schaik has over 20 years of global strategic marketing, social media and public relations expertise in sports, sponsorship, media and business, producing award winning and cutting-edge programs designed to increase ROI and minimize cost. He has worked with confederations, organizing committees, leagues and teams from around the world and with many of today's best athletes; ranging from Super Bowl winners and NBA All Stars to World- and Olympic C...

  14. An Application of Formal Argumentation: Fusing Bayes Nets in MAS

    DEFF Research Database (Denmark)

    Nielsen, Søren Holbech; Parsons, Simon

    2006-01-01

    to reach the compromise by gradually agreeing on parts of it. In the metaphor of the variable, the agents should be able to agree on successively smaller subsets of the enormous state space. However, these same local relationship can interact, and understanding the extent to which partial agreements affect...... the possible final compromise is a highly complex task. In this work we suggest using formal argumentation as the reasoning mechanism for agents solving this task, and suggest an open-ended agora approach that ensures agents high quality compromises in an anytime fashion....

  15. MAS architecture and knowledge model for vehicles data communication

    Directory of Open Access Journals (Sweden)

    Emmanuel ADAM

    2012-07-01

    Full Text Available Normal 0 21 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-ansi-language:EN-US;} Completely autonomous vehicles in traffic should allow to decrease the number of road accident victims greatly, and should allow gains in terms of performance and economy. Modelling the vehicles interaction, and especially knowledge sharing, is one of the main challenges to optimize traffic flow with autonomous vehicles. We propose in this paper a model of knowledge communication between mobile agents on a traffic network. The model of knowledge and of interaction enables to propagate new knowledge without overloading the system with a too large number of communications. For that, only the new knowledge is communicated, and two agents communicate the same knowledge only once. Moreover, in order to allow agents to update their knowledge (perceived or created, a notion of degradation is used. A simulator has been built to evaluate the proposal, before to implement it in mobile robots. Some results of the simulator are proposed in this article.

  16. MAS Based Event-Triggered Hybrid Control for Smart Microgrids

    DEFF Research Database (Denmark)

    Dou, Chunxia; Liu, Bin; Guerrero, Josep M.

    2013-01-01

    This paper is focused on an advanced control for autonomous microgrids. In order to improve the performance regarding security and stability, a hierarchical decentralized coordinated control scheme is proposed based on multi-agents structure. Moreover, corresponding to the multi-mode and the hybrid...... haracteristics of microgrids, an event-triggered hybrid control, including three kinds of switching controls, is designed to intelligently reconstruct operation mode when the security stability assessment indexes or the constraint conditions are violated. The validity of proposed control scheme is demonstrated...

  17. Advances in 27Al MAS NMR studies of geopolymers

    Czech Academy of Sciences Publication Activity Database

    Brus, Jiří; Abbrent, Sabina; Kobera, Libor; Urbanová, Martina; Cuba, P.

    2016-01-01

    Roč. 88, č. 2016 (2016), s. 79-147 ISSN 0066-4103 R&D Projects: GA ČR(CZ) GA13-24155S; GA MŠk(CZ) LO1507 Institutional support: RVO:61389013 Keywords : geopolymers * aluminosilicates * solid-state NMR Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.600, year: 2016

  18. An Application of Formal Argumentation: Fusing Bayes Nets in MAS

    DEFF Research Database (Denmark)

    Nielsen, Søren Holbech; Parsons, Simon

    2006-01-01

    from each BN. The task can be characterized as the need for agents to agree on a specific state (a BN) of a variable with an enormous state space (all possible BNs). The grandness of the task is reduced by the fact that BNs are composed of local relationships, and it should therefore be possible...

  19. A Vision in Jeopardy: Royal Navy Maritime Autonomous Systems (MAS)

    Science.gov (United States)

    2017-03-31

    9 Albert Palazzo, “The Military Revolution of Limits and the Changing Character of War,” Small Wars Journal, (October, 2013), http...security analyst Francis Hoffman contends “culture is not a driver or a prescriptive barrier,” in essence he too agrees; “military culture serves as a...Francis. G. Hoffman , “Learning While Under Fire: Military Change in Wartime” unpublished Ph.D. dissertation, War Studies Department, School of

  20. MAS architecture and knowledge model for vehicles data communication

    OpenAIRE

    Emmanuel ADAM; Emmanuelle GRISLIN-LE STRUGEON; René MANDIAU

    2012-01-01

    Completely autonomous vehicles in traffic should allow to decrease the number of road accident victims greatly, and should allow gains in terms of performance and economy. Modelling the vehicles interaction, and especially knowledge sharing, is one of the main challenges to optimize traffic flow with autonomous vehicles. We propose in this paper a model of knowledge communication between mobile agents on a traffic network. The model of knowledge and of interaction enables to propagate new ...

  1. Libros y mas libros: Recommended Children's Books in Spanish.

    Science.gov (United States)

    Schon, Isabel

    2000-01-01

    Provides an annotated bibliography of recommended Spanish-language children's books. A total of 15 books are grouped in the following categories: (1) books for the very young; (2) fiction; (3) folklore; (4) literature; (5) poetry; and (6) history. (EV)

  2. UNIVERSIDAD, CIENCIA Y DESARROLLO: MAS ALLA DE LA LINEA BASE

    Directory of Open Access Journals (Sweden)

    Orlando Pulido Chaves

    1996-01-01

    Full Text Available Este artículo plantea la hipótesis de que la actual crisis a escala global es producto de un cambio en el modelo de desarrollo del capitalismo, consistente en una transformación sustancial de los procesos productivos, y de la transición hacia una nueva fase del capitalismo, caracterizada por el hecho de que las hegemonías y las supremacías se empiezan a construir con base en el predominio del desarrollo científico y tecnológico. Esta crisis expresa el agotamiento del modelo fordista-taylorista, sustentado en la gran industria y en el control del mercado mundial de bienes manufacturados y de capital, y la aparición de tendencias postfordistas, caracterizadas por la lucha por el control del mercado de servicios y de bienes de alta densidad tecnológica, en el que la producción de conocimiento domina las relaciones comerciales.. En este contexto, la universidad, la educación y la investigación cobran importancia estratégica, y plantean retos decisivos para el futuro de los países subdesarrollados.

  3. Broadband MAS NMR spectroscopy in the low-power limit

    Science.gov (United States)

    Sanders, Kevin J.; Pell, Andrew J.; Wegner, Sebastian; Grey, Clare P.; Pintacuda, Guido

    2018-04-01

    We investigate the performance of broadband adiabatic inversion pulses in the high-power (short high-powered adiabatic pulse, SHAP) and low-power (single-sideband-selective adiabatic pulse, S3AP) RF regimes on a spin system subjected to large anisotropic interactions. We show by combined experimental results and spin dynamics simulations that when the magic-angle spinning rate exceeds 100 kHz S3APs begin outperforming SHAPs. This is especially true for low-gamma nuclei, such as 6 Li in paramagnetic Li-ion battery materials. Finally, we show how S3APs can be improved by combining multiple waveforms sweeping over multiple sidebands simultaneously, in order to produce inverted sideband profiles free from intensity biasing.

  4. MAS approach to political prospection and alliance analysis

    Directory of Open Access Journals (Sweden)

    Araceli N. PROTO

    2011-03-01

    Full Text Available The generalization of the Lotka-Volterra model (GLVM, to the N agents case is used in this contribution. The model is applied to model party alliances before election processes, as well as to prospect the final horizons of different candidates in Argentinian future elections which will take place on October 2011. The parameters of the model are setting using public polls. Romanian polls are used to validate the ansatzabout the meaning of the parameters considering the available data, as this election results are known.

  5. 48 CFR 538.272 - MAS price reductions.

    Science.gov (United States)

    2010-10-01

    ... maintain during the contract period the negotiated price/discount relationship (and/or term and condition relationship) between the eligible ordering activities and the offeror's customer or category of customers on... customers) that results in a less advantageous relationship between the eligible ordering activities and...

  6. Norma juht hämas Venemaa osas / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2005-01-01

    Norma juhatuse esimees Peep Siimon teatas osalise tööaja rakendamise vajadust 551 töötaja puhul ning põhjendab seda keerulise olukorraga Venemaal. Diagramm: Vene autoturg kasvab. Vt. samas: Eesti analüütikud osalise tööaja teadet ei pelga. Kommenteerib Valentin Jurkin

  7. Las logias masónicas. Una sociabilidad pluriformal

    Directory of Open Access Journals (Sweden)

    Luis P. Martín

    2003-08-01

    Full Text Available Freemasonry, as the prototype of organized sociability par excellence, was created around a space, and not the reverse, so that the lodge was by nature the ultimate seat of masonic sociability. In this study, we shall attempt to explain the diverse forms of the lodge, from the point of view of sociability. While we are examining a multifarious society, we should not forget that it also has a powerful normative standard in regard to socialization. The lodge is an organized space, with multiple functions (educational, spiritual, cultural, political, but it is also a place in which symbolism appropriates that space, which can be entered only by means of a series of initiation rites. The masonic lodge has cultural antecedents that predefine a social space and structure a kind of multiple sociability. In this article we will address the object, function and use of the masonic lodge.

  8. La lucidez es la herida mas cercana al sol

    Directory of Open Access Journals (Sweden)

    Juan E. Manuel Roca

    2015-01-01

    Full Text Available La comunicación interpersonal, muchas veces es dejada de lado por los comunicólogos, sin embargo tiene suma gravitación en las relaciones cotidianas entre las personas y en los procesos comunicacionales, toca el lenguaje de los gestos, la (in comunicación política, ceremonial y protocolo, intermediación en la comunicación, los jóvenes se incomunican. Respecto al Periodismo Investigativo señala que a pesar de los riesgos que implica el periodismo investigativo, muchos profesionales de América Latina no dudan en practicarlo, escudriñando muchas veces en temas que de no ser por ellos permanecerían ocultos. En otro artículo se habla de la importante repercusión que tuvo en América Latina el concurso CHASQUI, el que contó con la participación de profesionales de todo el continente. Incluye la entrega de entrevistas a destacados comunicadores de América Latina. Una sección está dedicada a las nuevas tecnologías: red de noticias y transmisiones vía satélite.

  9. CONSUMIDOR DE PRODUTOS VIRTUAIS: USA, MAS NÃO COMPRA

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    Jairo Simião Dornelas

    2010-03-01

    Full Text Available Produtos virtuais são aqueles que podem ser enviados do produtor ao consumidor pela Internet. Analisando a experiência da D'Accord Music Software, que está obtendo destaque na venda de software pela Internet, detectou-se um comportamento defensivo dos consumidores para comprar produtos virtuais. Tal comportamento manifesta-se na baixa taxa de conversão entre usuários que testam e os que realmente compram. Este trabalho visa justamente a aprofundar o conhecimento sobre o comportamento de compra do consumidor destes produtos, destacando a adoção do marketing experiencial como resposta aos desafios. A pesquisa foi conduzida através de entrevistas com os empreendedores e a aplicação de um e-survey, com uma amostra de 700 usuários. As conclusões indicam que o fator preço tem maior importância sob a ótica dos consumidores: a virtualidade parece ser de menor relevância. Como resgate do campo, cogita-se que a adoção do marketing experiencial pode ser uma importante estratégia mercadológica para cativar clientes e reduzir seu comportamento defensivo.

  10. MAS architecture and knowledge model for vehicles data communication

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    René MANDIAU

    2013-07-01

    Full Text Available Normal 0 21 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-ansi-language:EN-US;} Completely autonomous vehicles in traffic should allow to decrease the number of road accident victims greatly, and should allow gains in terms of performance and economy. Modelling the vehicles interaction, and especially knowledge sharing, is one of the main challenges to optimize traffic flow with autonomous vehicles. We propose in this paper a model of knowledge communication between mobile agents on a traffic network. The model of knowledge and of interaction enables to propagate new knowledge without overloading the system with a too large number of communications. For that, only the new knowledge is communicated, and two agents communicate the same knowledge only once. Moreover, in order to allow agents to update their knowledge (perceived or created, a notion of degradation is used. A simulator has been built to evaluate the proposal, before to implement it in mobile robots. Some results of the simulator are proposed in this article.

  11. Kıbrıs Mülkiyet Tartışmasına Taşınmaz Mal Komisyonu Açısından Bir Bakış Cyprus Property Dispute through the Glance of Immovable Property Commission

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    Derya ÖZVERİ

    2013-07-01

    Full Text Available The ‘property dispute’ of the Cyprus issue is just one of many layers of the problem. Not only, is it related to the fundamental rights of around 210,000 internally displaced people of the island, but it will also be a focal parameter to economic and social ends in the event of reunification. After presenting a brief historical overview of the problem and the two official positions of both Turkish and Greek sides - the achievement of ‘bizonality’ and the restoration of ‘human rights-, this article seeks to elaborate these two specific positions with a special focus of the cases of Loizidou v. Turkey and Xenides-Arestis v.Turkey in European Court of Human Rights which put the Immovable Property Commission in the focus for the restoration of property claims of displaced people throughout the island. The article argues that the exhaustion of domestic remedies through the Immovable Property Commission could give a new impetus on the negotiation table to the property issue against all odds. Besides this new institutional structure given by the Immovable Property Commission could set a new venue for solving the dispute which has been always in a deadlock for so many years with both parties and with their unarguable positions. Mülkiyet tartışması, Kıbrıs sorununun, çok katmanlı ve yıllardır çözüm bekleyen konularından sadece biri olarak görünse de; ada içinde yerlerinden olmuş 210.000´e yakın kişiyi ilgilendiren ve tüm adanın sosyo-ekonomik ve kültürel yapısını temelinden değiştiren bir olgu olarak karşımıza çıkmaktadır..Mülkiyet tartışmasının çok önemli bir uzlaşmazlık konusu olması ayrıca, adanın tekrar birleşmesi ihtimalinde de bu konunun yine barış masasına yatırılacak ve görüşmeleri kökünden degiştirecek yapıda bır sorun olmasından da kaynaklanmaktadır. Bu çalışma da, mülkiyet tartışmasının adanıngeleceği içindeki önemini, öncelikle tarihsel arka plan

  12. Problēmas un iespējamie risinājumi kriminālatbildības piemērošanai par bordeļu izveidošanu, uzturēšanu, vadīšanu vai finansēšanu

    OpenAIRE

    Bočs, Lauris

    2012-01-01

    Bakalaura darba mērķis ir noteikt mūsdienu bordeļu kā prostitūcijas sniegšanas un organizēšanas vietu darbības izpratnes nepilnības, normatīvo regulējumu un ar to saistītās problēmas kriminālatbildības piemērošanai par bordeļu izveidošanu, uzturēšanu, vadīšanu vai finansēšanu Latvijas Republikā. Īstenojot mērķi, tiek aprakstīti iespējamie nelegālās prostitūcijas cēloņi, sniegti atbilstoši priekšlikumi cēloņu mazināšanai, un skaidrotas legālās prostitūcijas sniegšanas un organizēšanas īpatn...

  13. Ratio changes of selected components of body composition after lymphatic massage [Změny poměrů vybraných složek tělesného složení po lymfatické masáži

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    Jarmila Riegerová

    2009-12-01

    Full Text Available BACKGROUND: The application of lymphatic massages has a highly preventive effect as it reinforces the drainage and transport functions of the lymph pump and thus activates the lymphatic flow and helps detoxify the body. OBJECTIVE: This pilot report inquires into the effect of lymphatic massages on selected components of body composition. METHODS: We conducted an examination of body composition using the InBody 720 device (multifrequency bioelectrical impedance analysis in a population of 30 women before and after having received practical training in lymphatic massages. Our study has pilot features due to professional selection and the low number of participants. We have presented a data analysis which defines the population anthropometrically (in terms of body height and weight and body mass index, waist hip ratio, body fat mass, skeletal muscle mass, rate changes in body water (total body water, intracellular water, extracellular water, proteins, total minerals, bone mineral content and changes to Edema indexes. RESULTS: A significant reduction of total body water (p = 0.042, phi = 0.0 and Edema 2 (p = 0.021, phi = 0.1 was indicated in the massaged area. In the case of Edema 1, significant effects of lymphatic massage were determined in both the right (p = 0.042, phi = 0.4 and the left (p = 0.012, phi = 0.2 upper extremity, and the left lower extremity (p = 0.014, phi = 0.2. Significant differences in Edema 2 were found in both the upper and lower extremities (p < 0.05 between the 1st and 2nd examination. A reduction and equilibration to the standard deviation values was also shown. CONCLUSIONS: Our results suggest the necessity of repeating the experiment in a different time frame. We confirm the positive intervention of lymphatic massage on the interstitium and cellular body environment. [Na dvou výukových kurzech lymfatických masáží jsme ve druhé polovině kurzu provedli vyšetření složení těla přístrojem InBody 720. Vy

  14. Neonatal administration of fluoxetine did not alter the anxiety indicators, but decreased the locomotor activity in adult rats in the elevated plus-maze Administração neonatal de fluoxetina não alterou os indicadores de ansiedade, mas diminuiu a atividade locomotora em ratos adultos no labirinto elevado em cruz

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    Valdenilson Ribeiro Ribas

    2008-12-01

    Full Text Available The objective of this study was evaluate the anxiety and locomotor activity (LA in 52 Wistar adult male rats, being 26 treated with fluoxetine (10 mg/Kg - sc in the neonatal period. These same rats received foot shock (FS (1.6-mA - 2-s in the 90th day. The anxiety and LA were appraised by plus-maze. The time spent in the open arms was used as anxiety index and the LA was measured by number of entries in closed arms (NECA and the total of entries (TE. T-test was used with pO objetivo deste estudo foi avaliar a ansiedade e a atividade locomotora (AL em 52 ratos Wistar adultos machos, sendo 26 tratados no período neonatal com fluoxetina (10 mg/Kg - sc e no 90º dia, receberam estímulos elétricos nas patas (1,6-mA-2-s. A ansiedade e a AL foram avaliadas por meio do labirinto elevado em cruz. O tempo de permanência dos animais nos braços abertos (BA foi utilizado como índice de ansiedade e a AL medida pelo número de entradas nos braços fechados (NEBF e pelo total de entradas (TE nos BA e BF. O teste t foi utilizado, com (p<0,05 e os dados apresentados em média±erro padrão. Os animais tratados reduziram o NEBF (2,35±0,33 e o TE (3,96±0,61 comparados a seus controles (4,65±0,52 e (6,96±0,94. A administração neonatal de fluoxetina não alterou a ansiedade, mas diminuiu a AL dos animais que receberam EE.

  15. Lithium ion mobility in lithium phosphidosilicates: Crystal structure, {sup 7}Li, {sup 29}Si, and {sup 31}P MAS NMR spectroscopy, and impedance spectroscopy of Li{sub 8}SiP{sub 4} and Li{sub 2}SiP{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Toffoletti, Lorenzo; Landesfeind, Johannes; Klein, Wilhelm; Gasteiger, Hubert A.; Faessler, Thomas F. [Department of Chemistry, Technische Universitaet Muenchen, Lichtenbergstrasse 4, 85747, Garching bei Muenchen (Germany); Kirchhain, Holger; Wuellen, Leo van [Department of Physics, University of Augsburg, Universitaetsstrasse 1, 86159, Augsburg (Germany)

    2016-12-05

    The need to improve electrodes and Li-ion conducting materials for rechargeable all-solid-state batteries has drawn enhanced attention to the investigation of lithium-rich compounds. The study of the ternary system Li-Si-P revealed a series of new compounds, two of which, Li{sub 8}SiP{sub 4} and Li{sub 2}SiP{sub 2}, are presented. Both phases represent members of a new family of Li ion conductors that display Li ion conductivity in the range from 1.15(7) x 10{sup -6} Scm{sup -1} at 0 C to 1.2(2) x 10{sup -4} Scm{sup -1} at 75 C (Li{sub 8}SiP{sub 4}) and from 6.1(7) x 10{sup -8} Scm{sup -1} at 0 C to 6(1) x 10{sup -6} Scm{sup -1} at 75 C (Li{sub 2}SiP{sub 2}), as determined by impedance measurements. Temperature-dependent solid-state {sup 7}Li NMR spectroscopy revealed low activation energies of about 36 kJ mol{sup -1} for Li{sub 8}SiP{sub 4} and about 47 kJ mol{sup -1} for Li{sub 2}SiP{sub 2}. Both compounds were structurally characterized by X-ray diffraction analysis (single crystal and powder methods) and by {sup 7}Li, {sup 29}Si, and {sup 31}P MAS NMR spectroscopy. Both phases consist of tetrahedral SiP{sub 4} anions and Li counterions. Li{sub 8}SiP{sub 4} contains isolated SiP{sub 4} units surrounded by Li atoms, while Li{sub 2}SiP{sub 2} comprises a three-dimensional network based on corner-sharing SiP{sub 4} tetrahedra, with the Li ions located in cavities and channels. (copyright 2016 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  16. “Sınıf Genelinde Akran Öğretimi” (SGAÖ Stratejisinin Karma Öğrenme Yeterlilikleri / Yetersizlikleri Olan Öğrencilerin Devam Ettiği İlkokul Sınıfında Etkililiğinin İncelenmesi: Bir Vaka Çalışması

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    Charikleia Ntoliou

    2016-04-01

    Full Text Available Bu araştırmanın amacı öğrenme güçlükleri olan öğrencilerin genel eğitim sınıflarına bütünleştirilmesinde etkili bir eğitim yöntemi olan Sınıf Genelinde Akran Öğretimi (SGAÖ stratejisini tartışmaktır. SGAÖ‟nün tanıtılmasına ek olarak, bu makale Yunanistan‟da bir ilkokulun ikinci sınıfında sınıf öğretmeninin öğretici bir araştırmacı ile işbirliğine dayalı olarak çalışarak SGAÖ‟nün öğrencilerin sözcük okuma performanslarına etkisinin programa dayalı değerlendirmeler ile incelendiği bir vaka çalışmasını sunmaktadır. Araştırmanın sonuçları, öğrenme güçlüğü tanısı alma riski olan öğrenciler de dahil tüm öğrencilerin performanslarının arttığını göstermektedir. Makale, yöntemin tartışılması ve ileride yapılacak araştırma ve uygulamalara ilişkin öneriler ile son bulmaktadır. The purpose of this article is to discuss ClassWide Peer Tutoring (CWPT strategy as an effective educational procedure in including students with learning disabilities in general education classroom. In addition to describing CWPT, this article mainly presents a case study in which a primary educator teacher worked collaboratively with an educational researcher in a second grade Greek classroom to examine the impact of CWPT on students‟ word-spelling performance, as monitored on curriculum-based assessments. Data were collected by applying pre- and post-tests. Results indicated that all students, including those being at risk of having learning disabilities, improved their performance. The article concludes with a discussion of the procedure and areas of future research and application.

  17. Erros mais comuns e fatores de risco na administração de medicamentos em unidades básicas de saúde Errores mas comunes y factores de riesgo en la administración de medicamentos en las unidades básicas de salud Common errors and risk factors in medicine administration at basic health units

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    Viviane Tosta de Carvalho

    1999-12-01

    Full Text Available Este estudo identificou e analisou as opiniões de enfermeiros e profissionais de enfermagem sobre os fatores de risco mais comuns à ocorrência dos erros na administração de medicamentos, as conseqüências, intervenções tomadas e medidas que minimizariam essa ocorrência. Para tanto, aplicou-se um instrumento para coleta de dados contendo questões sobre as opiniões de profissionais de enfermagem, atuantes em Unidades Básicas de Saúde de uma cidade do interior paulista. Os resultados indicaram que os fatores de risco associados ao próprio profissional foram a falta de atenção e dificuldade de entender prescrições médicas. As intervenções tomadas estão relacionadas à punição e educação e as propostas para minimizar as ocorrências dos erros foram a orientação e reciclagem dos profissionais envolvidos.Este estudio, de carácter cuantitativo, identificó y analizó los factores de riesgo mas comunes para la aparición de errores durante la administración de medicamentos, las consecuencias y medidas que disminuían la ocurrencia de los mismos, según las opiniones de los profesionales de enfermería de las unidades básicas de salud de una cuidad del interior de São Paulo. Los factores de riesgo asociados al propio profesional fueron la falta de atención y dificultad para entender las prescripciones médicas. Las intervenciones tomadas frente al error fueron el castigo, y la educación. Dentro de las propuestas para disminuir las ocurrencias de errores para este grupo de personas fueron la orientación, y la educación de los profesionales involucrados.The present study identified and analyzed the opinions of nurses and nursing professionals about the more common risk factors regarding errors in medicine administration as well as the consequences, interventions and measures to minimize this problem. Therefore, the authors applied an instrument of data collection with questions on the opinions of the nursing professionals

  18. A frágil confiabilidade do tribunal de contas de Santa Catarina na fiscalização dos recursos da educação: governo estadual deixou de aplicar mais de R$ 2,1 bilhões em educação de 1998 a 2008 mas TC aprovou as contas estaduais

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    Nicholas Davies

    2011-10-01

    Full Text Available Doi:10.5007/2175-795X.2011v29n1p193 O estudo examinou procedimentos adotados pelo Tribunal de Contas de Santa Catarina para a verificação da receita e despesa em educação, com base em seus relatórios sobre as contas estaduais de 1998 a 2008, e chegou a vários resultados, alguns indicados a seguir. Entre os aspectos positivos cabe ressaltar (1 o registro da ilegalidade e inconstitucionalidade do governo estadual em subtrair impostos da educação e saúde através de mecanismos de desvinculação, como o SEITEC e o Fundo Social e (2 o descumprimento de várias exigências constitucionais e legais. Entre os pontos negativos cabe destacar (1 a provável confusão entre gastos na função orçamentária Educação (definida pela Lei no 4.320 e em MDE (definida pelos artigos 70 e 71 da LDB, (2 a aceitação da contabilização das despesas educacionais por órgãos diferentes, contrariando o que estabelece a LDB, (3 a oscilação nos critérios de despesas, ora empenhadas, ora liquidadas, ora pagas, e (4 a falta de uma posição firme sobre a inclusão dos inativos no cálculo das despesas legais em MDE, adotando dois cálculos (com e sem inativos, mas na prática contabilizando os inativos no cálculo do percentual mínimo. A debilidade maior do TC, no entanto, foi o fato de ele, apesar de ter constatado que o governo estadual não aplicou o percentual mínimo (25% dos impostos em educação, nem os 15% dos impostos no ensino fundamental, nem a receita do Fundef, não emitiu parecer prévio contrário à aprovação das contas estaduais, limitando-se a fazer ressalvas e recomendações, quase sempre descumpridas pelo governo estadual, o que levanta a questão  sobre a utilidade do TC.

  19. Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model Azul de metileno melhora as condições hemodinâmicas do choque circulatório, mas aumenta a peroxidação lipídica em um modelo suino de pancreatite aguda grave

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    Roberto Ferreira Meirelles Jr

    2008-01-01

    pancreático para estudo histopatológico. RESULTADOS: No grupo PA a pressão arterial media (PAM e o débito cardíaco (DC diminuíram respectivamente 33% (p0.05. Após a indução da PA a infusão de AM não reverteu as quedas da PA e DC. Não houve diferenças nos níveis de amilase sérica e achados histológicos com o tratamento com o azul de metileno. CONCLUSÕES: No presente modelo de PA induzida por taurocolato o AM retardou o desenvolvimento do choque circulatório, diminuiu os níveis de nitrato mas aumentou os níveis de MDA. Não se realizou nenhum tipo de reposição volêmica que poderia melhorar a perfusão tecidual e melhora da microcirculação. Investigações adicionais são necessárias para elucidar o papel terapêutico do AM no tratamento da PA aguda.

  20. Üstün Yetenekli Çocukları Belirlemede Öğretmen Öncelikleri: İkili Karşılaştırma Yöntemiyle Bir Ölçekleme Çalışması

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    Eren Halil Özberk

    2016-08-01

    Full Text Available Bu çalışmanın amacı üstün yetenekli çocukları belirlemede öğretmen önceliklerinin tespit edilmesidir. Bu doğrultuda alanyazına ve uzman görüşüne dayalı olarak üstün yetenekli bireylere ait özellikler belirlenmiş, ardından bu öğrencileri seçmede en önemli referans kaynağı olan öğretmenlere bu kriterler sunularak onların görüşlerine göre ölçekleme yöntemi ile önem dereceleri tespit edilmiş ve bu önem derecelerinin öğretmenlerin demografik özelliklerine göre nasıl değişkenlik gösterdiği incelenmiştir. Bu amaçla ölçekleme çalışmasında üstün yetenekli öğrencilerin özellikleri yedi ifade altında toplanmıştır. Araştırmada Ankara ili merkez ilçelerinde bulunan 785 öğretmenden bu 7 özelliği ikili karşılaştırma yaparak sıralamaları istenmiştir. Yapılan ölçekleme işlemi sonunda öğretmenlerin üstün yetenekli çocukları belirlemede ilk önce tercih ettiği özellik, çevreye ve sosyal olaylara karşı duyarlı olması, son tercih ettiği özellik ise arkadaş çevresinde liderlik özelliğine sahip olması olmuştur. Öğretmenlerin demografik özelliklerine göre önem sıralamasında ise üstün yetenekli çocukları belirlemede ilk tercih edilen özellik, çevreye ve sosyal olaylara karşı duyarlı olması olmuştur. The aim of the research is to determine teacher priorities on identifying gifted children. The study is based on the principle of comparison of seven different specifications which were determined by literature and professionals majored in gifted education according to the judgments of the primary and secondary school teachers using pairwise comparison method according to various demographic variable. In that particular scaling study, specifications of gifted children have been summarized in seven statements. These seven statements have been asked 785 teachers in Ankara province to compare by using pairwise comparison. As a result of scaling study

  1. Quem sente é a gente, mas é preciso relevar: a lombalgia na vida das trabalhadoras do setor têxtil de Blumenau - Santa Catarina One feels it but one must overlook it: low back pain in the life of women working in the textile sector of Blumenau - Santa Catarina

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    Karine Muniz Polizelli

    2010-06-01

    Full Text Available Este estudo foi desenvolvido com o objetivo de compreender o enfrentamento da lombalgia no cotidiano de mulheres trabalhadoras do setor têxtil de Blumenau, Santa Catarina. Três mulheres trabalhadoras do setor têxtil daquela cidade foram as informantes principais do estudo, desenvolvido em encontros quinzenais e visitas a locais de trabalho. Foram utilizados como ferramentas de estudo um calendário com data e dias da semana para a marcação de dores relativas à lombalgia e uma Escala Análogo Visual (EAV. Além de relatos anotados em formulários de acompanhamento dos encontros quinzenais, utilizou-se um diário de campo para transcrição de fatos e relatos. Os dados coletados levaram à construção de duas categorias interpretativas: a dor lombar sob o aspecto da normalidade e a dor sentida. Os resultados da pesquisa levam à conclusão de que a lombalgia, sob o ponto de vista das trabalhadoras do setor têxtil de Blumenau, apresenta-se como uma espécie de conflito entre a dor normal, sem importância social, e a dor sentida e limitante, que traz sofrimentos e angústias no âmbito privado. A dualidade da lombalgia é marcante, pois são mulheres que têm dor, real para elas, com um impacto importante para suas vidas, mas elas mesmas esforçam-se por negligenciá-la, seguindo a concepção socialmente aceita para esta questão no contexto cultural da região. O conceito de lombalgia construído é de algo inerente à vida e ao trabalho, o que não permite o direito de estar doente.This study was developed with the objective of understanding how women working in the textile sector of Blumenau, state of Santa Catarina, cope with low back pain. Three women who worked in the textile sector of that city were the main informants of the study, developed in biweekly meetings and visits to workplaces. The study tools were a calendar with dates and week days, where the participants should mark the occurrence of low back pain, and a Visual Analog

  2. Les schémas réparateurs entre interaction et interactivité - A propos de l'apprentissage collaboratif en binôme autour d'un didacticiel de compréhension orale Repairing schemes between interaction and interactivity - On collaborative learning in pair work with an educational software for oral comprehension

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    Martine Eisenbeis

    2003-06-01

    Full Text Available Nous avons analysé, en nous référant au groupe-classe traditionnel, une situation particulière d'apprentissage en adoptant comme entrée la question des réparations et des réajustements: il s'agit d'une activité à  partir d'un didacticiel de compréhension orale sur la base de reportages télévisés et de questionnaires à remplir. Les apprenants mènent cette activité en binôme. Nous rappelons et analysons brièvement les différentes caractéristiques du schéma réparateur dans la classe de langue en général et dans les conversations authentiques. Nous établissons ensuite une comparaison à  partir de l'analyse de transcriptions des échanges qui ont donc lieu autour d'un support et dans un contexte très différents, comparaison qui se mène essentiellement sur la base des questions suivantes: l'organisation du schéma réparateur et l'initiative des réparations, l'objet des réparations (cf. notion de bifocalisation chez Bange, la forme des réparations (correction-injonction ou correction incitative? appréciation positive ou négative? La deuxième partie du travail vise à repérer les particularités des réparations mises en place dans ce dispositif et à cerner les incidences sur la manière dont la compréhension orale est travaillée. Notre objectif est de mettre en relation la modification des supports et des contextes avec les schémas réparateurs dans l'apprentissage d'une langue.A specific situation of learning has been analyzed, in reference to the traditional classroom, based on the notions of reparation and readjustment. The activity described relies on the use of an educational software for oral comprehension, based on television reports and forms to be filled in. This activity is organized in pairs. The different characteristics of repairing schemes in traditional language class and in authentic communication are briefly described. Then a comparison is made thanks to the analysis of the transcription of

  3. Sol-gel chemistry synthesis and DTA-TGA, XRPD, SIC and {sup 7}Li, {sup 31}P, {sup 29}Si MAS-NMR studies on the Li-NASICON Li{sub 3}Zr{sub 2-y}Si{sub 2-4y}P{sub 1+4y}O{sub 12} (0 Less-Than-Or-Slanted-Equal-To y Less-Than-Or-Slanted-Equal-To 0.5) system

    Energy Technology Data Exchange (ETDEWEB)

    Belam, W., E-mail: WahidBelam@yahoo.fr [Chemistry Department, Bizerta Science Faculty, 7021 Jarzouna, Bizerta (Tunisia)

    2013-02-25

    Highlights: Black-Right-Pointing-Pointer The samples of Li-NASICON were elaborated by sol-gel chemistry. Black-Right-Pointing-Pointer The calcined temperatures of the studied samples were deduced from their thermograms. Black-Right-Pointing-Pointer The recorded X-ray powder diffractograms were indexed in the rhombohedral system. Black-Right-Pointing-Pointer The synthesized Li-NASICON materials are excellent lithium fast cation conductors. - Abstract: Five selected compounds of Li-NASICON, Li{sub 3}Zr{sub 2-y}Si{sub 2-4y}P{sub 1+4y}O{sub 12} (0 Less-Than-Or-Slanted-Equal-To y Less-Than-Or-Slanted-Equal-To 0.5), were synthesized by sol-gel chemistry in order to obtain pure polycrystalline powder and then analyzed by different physicochemical characterizations such as coupled DTA (differential thermal analysis)-TGA (thermogravimetric analysis), XRPD (X-ray powder diffraction), CIS (complex impedance spectroscopy) and MAS (magic angle spinning)-NMR (nuclear magnetic resonance). So the calcined temperature of each sample has been deduced from its corresponding DTA-TGA thermogram. However, the recorded X-ray powder diffractograms were indexed in the rhombohedral system with R3{sup Macron }c space group which corresponds to the ideal structure of NASICON. Whereas, the complex impedance spectroscopy study showed that these Li-NASICON materials are excellent lithium fast cation conductors with total electric conductivity maximal value 1.97 Multiplication-Sign 10{sup -3} S cm{sup -1} at 293 K in the case of Li{sub 3}Zr{sub 1.5}P{sub 3}O{sub 12}. Furthermore, {sup 7}Li, {sup 31}P and {sup 29}Si MAS-NMR spectroscopy study and DFT/B3LYP theoretical calculations of chemical shifts were performed to discuss the ambiguousness that exists between the resonance peak number in the experimental spectrum and the crystallographic site number relative to Li{sub 3}Zr{sub 2}Si{sub 2}PO{sub 12}.

  4. Ziştovi ve Yaş Antlaşması Arasında Tuna Kıyısında Bir Osmanlı Kenti: Silistre (1791–1793 The Danube Coast Between The Treaty Of Ziştovi And Yaş An Ottoman City: Silistra (1791 – 1793

    Directory of Open Access Journals (Sweden)

    Hava SELÇUK

    2013-07-01

    ınınkarşılanmasında( zahire, peksimet, silah vs önemli bir fonksiyonasahipti. Bu çalışmada kaynak olarak iki antlaşma arasında kadılartarafından tutulan 50 Numaralı Şer’iyye Sicili (1791-1793kullanılmıştır. 50 Numaralı Şer’iyye Sicili Ziştovi ve Yaş Antlaşmasıöncesi ve bu antlaşmalar sonrası Silistre’nin siyasi, sosyal, ekonomik veaskeri meselelerine ışık tutacak bilgiler ihtiva etmektedir. Şer’iyyeSicilleri, Osmanlı toplumunun siyasî, iktisadî, hukukî ve içtimaîdurumlarının ortaya çıkarılmasında önemli kaynaklardır. BulgaristanArşivi “Nationale Biblioteque” de bulunan 50 Numaralı Silistre Şer’iyyeSicili çalışmamızın ana kaynağını oluşturmaktadır. Söz konusudefterde miras davaları, aile, görevli tayinleri, gemi yapımı, elçilik, vergi(zahire, duhan, adat-ı ağnam vb. konuların yer aldığı iktisadî, askerî veiçtimaî olayları içeren iki yüz otuz üç belge bulunmaktadır. Askerikonulara ışık tutacak konulardaki ferman, emir, buyruldular şer’iyyesicillerine kayıt edilmiştir. Eşkıyalık, zahirenin gemilerle taşınması,ihtida (din değiştirme, tanassur ve Nemçe esirleri konularıincelenmiştir. Silistre’nin 1791–1793 yıllarına ait sicil kayıtlarındanhareketle bölgenin toplumsal hayatı ortaya konulmuştur.

  5. " Mi mente decía no... mi cuerpo decía sí...": embarazo en adolescentes escolarizadas Minha mente falava não... mas meu corpo falava sim..." : Gravidez em adolescentes escolarizadas My mind said no... my body said yes...": Pregnancy in school adolescents

    Directory of Open Access Journals (Sweden)

    MARÍA ENRIQUETA CORTÉS ORTIZ

    etnografia focalizada, que se realizou durante um ano numa instituição educativa pública do Distrito de Aguablanca em Cali, Colômbia. Participaram como informantes chaves seis adolescentes mães escolarizadas e, como informantes gerais, quinze homens, quinze mulheres não grávidas, dez professores e treze pais de família. A pesquisa inclui entrevistas em profundidade e focus groups até atingir saturação de dados. O método utilizado para a análise foi o método Spradley. A partir da etnosemántica se identificaram quatro domínios relacionados com o gênero, a cultura, a educação e a decisão de ficar grávida. Adicionalmente, e baseado no estudo dos domínios a pesquisa conseguiu identificar e agrupar quatro temas culturais relacionados com o significado de ser mulher durante a adolescência, o estabelecimento das relações de gênero, o planejamento familiar e a realidade ante a decepção dos pais e a frustração do projeto de vida. As e os adolescentes se desenvolvem em contextos culturais de liberalidade, espacialidade e temporalidade que os predispõem e precipitam não só a viver a sexualidade rapidamente, mas a passar do amor romântico ao amor apaixonado.Sexuality, as a very important dimension of the human being, is affected by culture where the meaning and symbols are immersed and which express how adolescents experience it from their cosmovision. This study describes, from the perspective of gender roles, the decision making process in regard to pregnancy of school adolescents. The study was a focused ethnography that was carried out during one year in a public educational institution from the District of Aguablanca in Cali, Colombia. Key informants were six school adolescents who have become mothers and as general informants, fifteen men, fifteen nonpregnant women, ten teachers and thirteen parents. In depth interviews took place and focus groups until data saturation. The Spradley method was used for the analysis. Based on ethnosemantic, four

  6. “Mi mente decía no… mi cuerpo decía sí…”: el camino en decidir embarazarse las adolescentes escolarizadas My mind said no… my body said yes…”: Pregnancy in school adolescents Minha mente falava não… mas meu corpo falava sim…”: Gravidez em adolescentes escolarizadas

    Directory of Open Access Journals (Sweden)

    VÁSQUEZ TRUISSI MARTHA LUCÍA

    2009-12-01

    ênero, a cultura, a educação e a decisão de ficar grávida. Adicionalmente, e baseado no estudo dos domínios a pesquisa conseguiu identificar e agrupar quatro temas culturais relacionados com o significado de ser mulher durante a adolescência, o estabelecimento das relações de gênero, o planejamento familiar e a realidade ante a decepção dos pais e a frustração do projeto de vida. As e os adolescentes se desenvolvem em contextos culturais de liberalidade, espacialidade e temporalidade que os predispõem e precipitam não só a viver a sexualidade rapidamente, mas a passar do amor romântico ao amor apaixonado.

  7. İlhanlı Hâkimiyeti Altında Anadolu’da Siyasetin Temel Dinamiği: Göçebe Moğol-Türkmen Çatışması The Basic Dynamic Of Politics In Anatolia Under The Ilkhanid Rule: The Struggle Of Nomad Turcomans And Mongols

    Directory of Open Access Journals (Sweden)

    Halil ÇETİN

    2012-12-01

    ûk ve Türkiye Selçuklu devletleri ile göçebe Türkmenlerden müteşekkil bir ittifak buldular. Bunlar arasında Türkmenler, Moğolların siyasî amaçlarına ve askerî faaliyetlerine karşı en kararlı direnç noktasını oluşturmuşlardır. Gaza ülküsü gibi dinî motifler de içeren bu direniş, Türkmenlerin Anadolu’yu ısrarlı bir şekilde yurt edinme çabasının bir sonucudur. Esasen Anadolu’nun uç bölgelerine yoğun bir şekilde yerleşen Türkmenler için başka bir seçenek de kalmamıştır. Zira yarımadanın siyasî ve coğrafî sınırları onların bir başka bölgeye göçüne imkân da vermemiştir. Bunun içindir ki Türkmenlerin Anadolu’yu kararlı bir şekilde yurt edinme çabası ile Moğollara ısrarla karşı koymaları birbirini besleyen tavırlardır. Moğol ve Türkmen göçebeleri arasında uzun süren bu çatışmalar, Anadolu’da Selçuklu ve İlhanlı idaresinin çökmesiyle sonuçlanmıştır. Göçebe Türkmenler önde gelen siyasî aktörler olarak neticede Siyasal Türkmen Kimliği edinmişlerdir. XIV. asrın başlarında Anadolu’nun uç bölgelerinde ortaya çıkan Türkmen Beyliklerini kuran siyasî ve toplumsal zümrelerin bu kimliğin etkisinde oldukları görülmektedir. Örneğin Osmanlı Beyliği’nin kurucusu Osman Bey, İlhanlı hâkimiyeti altında Anadolu’da yaşanan Moğol-Türkmen çatışmasının ürünü olan siyasî yöntem, söylem ve araçları kullanmıştır.

  8. Ahmet Hamdi Tanpınar'ın Eserlerinde Trajik Olana Yol Açan Ölüm Hayat Çatışması Death-Life Conflict And ‘Tragic’ In The Ahmet Hamdi Tanpınar’s Works

    Directory of Open Access Journals (Sweden)

    Tolga BAYINDIR

    2013-07-01

    yanlarını ortaya koyan, onun düşüncelerini derinden etkileyen felsefî bir sorunsaldır. Ruhuyla ölümlü oluşunun farkındalığı, buna rağmen eserleriyle, maziyle, toplumla ve kültürle ölümsüzlüğü isteyişi/arayışı sanatçının eserlerindeki temel çatışma noktalarından birisini oluşturur. Bu çatışmayı yaratan uç değerler yaşam ve ölüm olarak ele alındığında, Ahmet Hamdi Tanpınar'ı kendi "eşiğinde" bulmak mümkün olacaktır. Tanpınar’ın özellikle günlükleri incelendiğinde görülür ki ölüm/ölümlü olma, ölümsüzlük onun yaratma/eser verme eyleminin altında yatan en önemli öğelerden birisidir. Böyle bir durum karşısında Tanpınar, eserlerinde kaçınılmaz olarak bilinç veya bilinçaltı düzeyinde ölüme dair imgeler kullanmaktadır. Yansıttığı bu ölüm anlayışının yanında onun hayata sıkı sıkıya bağlı yanlarını da keşfetmek mümkün hâle gelmektedir. Tanpınar’ın yaşamının son yıllarında ölüm karşısında belirgin bir kaygı duyduğu anlaşılmaktadır. Bu kaygının temelinde onun kendi içinde oluşturduğu ikiliğin sonuçlarını görmek mümkündür. O, dış olarak tanımladığı yaşamında, aslında olmak istediği kişi değildir ve iç dünyasında kurguladığı ben’inin çatışmasını yaşamaktadır. Bu makalede, kendi içinde yaşadığı bu çatışmanın dışa vurumu olarak Tanpınar’ın trajedisini oluşturan ölüm ve yaşam ikilemi üzerinde durulacaktır. Ayrıca, Ahmet Hamdi Tanpınar’ın “ölüm” kavramı üzerindeki düşünceleri temelinde söz konusu kavramın eserlerine yansıyışına farklı bir bakış açısı getirilmeye çalışılacaktır.

  9. EFEKTIVITAS ILMU NAHW DALAM PEMBELAJARAN BAHASA ARAB: Studi Kasus di Mas Simbang Kulon Pekalongan

    Directory of Open Access Journals (Sweden)

    Abd. Mu'in

    2012-10-01

    Full Text Available قـد تـعـلق تعـلم الـنحوبـتـعـلم اللـغـة الـعـربـية تـعـلقا قـويـا. اذا تـعلم شـخـص اللـغـة الـعـربيـة للـتـحـدث , فلـيـس بـواجـب أن يـهـتم النـحو اهـتـمـا ما كامـلا. الا اذا تـعـلم اللـغة الـعـربـية الـفـصـحـة الـصحـيـحـة فلا بـد أن يـتـعلـمـه تـعـلـما صـحـيـحا. لـذالك يـعـرف أن تـعـلم اللـغة الـعـربـية في المـدرسـة الـعـالـية الـسـلا فـية بسـيـمـبـانـج كـولـون يـهـتم ذلك كـله, حـتي يـرى ان تلامـيـذهـا يـسـتـطيـعـون أن يـقرأوا ويـتـرجـموا ويـسـتـمـعوا الـكلا م الـعـربي جـيـدا. اعـتـمـادا عـلي هـذا الـمـوقـع يـلا خـص أن عـلم الـنـحـومـفـيـد جـدا في اعـانـة تـعـلم اللـغـة الـعـربـية بـسـيـمـبانـج كـولـون. عـلـمـا أن نـتائـج اللـغـة الـعـربـية لأ كـثـر تـلا مـيذهـا أعـلي قـيـمـة (يـعـني بـين 78 – 80 عـلي حـسـب تـقـديـر الـقـيـمـة مـن الـمـدرسـة الـعالـية الـسلافـية بـسـبـانـج كـولـون فـكالـونـجـان (يـعـني بـين 70 – 76 . هذا يدل على أن تقدير القيمة التلاميذ فيها جيدا أو جيدا جدا.

  10. Tüüri ava(sta)mas, kuid mitte ainult / Igor Garšnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2011-01-01

    Kahest kontserdist Estonia kontserdisaalis - 4. märtsil ERSO ja Herbert Schuch (klaver) Olari Eltsi dirigeerimisel, kavas Tüüri Sümfoonia nr 8, Pärdi "Nekroloog" ja Ullmanni Klaverikontsert ning 10. märtsil Erkki-Sven Tüüri autorikontsert, kus esinesid Eesti Filharmoonia Kammerkoor ja Sinfonietta Riga Daniel Reussi juhatusel

  11. 77 FR 43084 - Multiple Award Schedule (MAS) Program Continuous Open Season-Operational Change

    Science.gov (United States)

    2012-07-23

    ... (GSA), Federal Acquisition Service (FAS) intends to institute a Demand Based Model (DBM) designed to...-4067. Mail: General Services Administration, Regulatory Secretariat (MVCB), Attn: Hada Flowers, 1275... GENERAL SERVICES ADMINISTRATION [Notice-QDA-2012-01; Docket No. 2012-0002; Sequence 17] Multiple...

  12. A new sensitive isotropic-anisotropic separation experiment—SPEED MAS

    Science.gov (United States)

    Strohmeier, Mark; Grant, David M.

    2004-06-01

    A new sensitive 2D isotropic-anisotropic separation experiment that utilizes stroboscopic phase encoding in the evolution dimension (SPEED) under magic angle sample spinning is presented. This 2D experiment consists of a train of 2 N-1 π pulses that are applied over 2 N rotor periods. The π pulse train effectively reduces the apparent spinning speed in the evolution dimension by a factor of 1/(2 N) from the mechanical spinning speed. Thus, problems commonly associated with magic angle turning such as stable slow spinning, different matching and TPPM proton decoupling conditions are avoided. Data replication similar to the five π replicated magic angle turning (FIREMAT) and pseudo 2D sideband suppression (P2DSS) experiments transfers resolution from the acquisition dimension to the evolution dimension. Hence, large spectral windows with good digital resolution are obtained with a few evolution increments. Here, slow spinning sideband patterns are extracted from the replicated 2D dataset with TIGER processing. Nevertheless, 2D Fourier transformation is also applicable. The extracted sideband patterns are identical to magic angle turning sideband pattern allowing for easy extraction of principal shift components. Accurate 13C principal shift components are obtained for 3-methylglutaric acid using SPEED and FIREMAT experiments to validate the method. Furthermore, SPEED spectra for calcium acetate and α santonin are reported to show the wide applicability of this new experiment.

  13. Açılış Konuşması

    Directory of Open Access Journals (Sweden)

    Masum Burak

    2013-11-01

    Full Text Available Düzenlemiş olduğumuz bu çalıştay ile kanatlı atıkları konusundaki paydaş kuruluş temsilcilerini üretimin yoğun olarak yapıldığı Bolu ilimizde bir araya getirerek mevcut durumun tespiti, atık işlemedeki yöntemler ve son gelişmelerle ilgili beyin fırtınası yapılarak çözüm odaklı öneriler ortaya konmaya çalışılmıştır.

  14. Maestras, Mujeres y Mas: Creating Teacher Networks for Resistance and Voice

    Science.gov (United States)

    Montano, Theresa; Burstein, Joyce

    2006-01-01

    This ethnographic case study documents the socialization of Chicana teachers entering the teaching profession within the past 5 years. As college students, they were actively involved in social justice issues. The belief system of these teachers is based on critical pedagogy, multicultural and antiracist education, and Chicano/a studies--the…

  15. Main karst and caves of Switzerland; El karst y las cuevas mas importantes de Suiza

    Energy Technology Data Exchange (ETDEWEB)

    Jeannin, P. Y.

    2016-07-01

    This paper presents an overview of the main karst areas and cave systems in Switzerland. The first part encloses descriptions of the main geological units that hold karst and caves in the country and summarizes a brief history of research and protection of the cave environments. The second part presents three regions enclosing large cave systems. Two regions in the Alps enclose some of the largest limestone caves in Europe: Siebenhengste (Siebenhengste cave system with ∼160 km and Barenschacht with 70 km) and Bodmeren-Silberen (Holloch cave system with 200 km and Silberen System with 39 km). These systems are also among the deepest with depths ranging between 880 and 1340 m. The third example is from the Jura Mountains (northern Switzerland). (Author)

  16. 6Li MAS NMR Study of Lithium Insertion into Hydrothermally Prepared Li-Ti-O Spinel

    Czech Academy of Sciences Publication Activity Database

    Krtil, Petr; Dědeček, Jiří; Kostlánová, Tereza; Brus, Jiří

    2004-01-01

    Roč. 7, č. 7 (2004), A163-A166 ISSN 1099-0062 R&D Projects: GA ČR GA203/03/0823 Institutional research plan: CEZ:AV0Z4040901 Keywords : lithium insertion * spinel * NMR Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.271, year: 2004

  17. HR-MAS NMR metabolomics of 'Swingle' citrumelo rootstock genetically modified to overproduce proline.

    Science.gov (United States)

    de Oliveira, Caroline S; Carlos, Eduardo F; Vieira, Luiz G E; Lião, Luciano M; Alcantara, Glaucia B

    2014-08-01

    The accumulation of proline is a typical physiological response to abiotic stresses in higher plants. 'Swingle' citrumelo, an important rootstock for citrus production, has been modified with a mutated Δ(1)-pyrroline-5-carboxylate synthetase gene (VaP5CSF129A) linked to the cauliflower mosaic virus 35S promoter to induce the overproduction of free proline. This paper presents a comparative metabolomic study of nontransgenic versus transgenic 'Swingle' citrumelo plants with high endogenous proline. (1)H high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and multivariate analysis showed significant differences in some metabolites between the nontransgenic and transgenic leaves and roots. The overproduction of proline has reduced the sucrose content in transgenic leaves, revealing a metabolic cost for these plants. In roots, the high level of free proline acts for the adjustment of cation-anion balance, causing the reduction of acetic acid content. The same sucrose level in roots indicates that they can be considered as sucrose sink. Similar behavior may be waited for fruits produced on transgenic rootstock. Copyright © 2014 John Wiley & Sons, Ltd.

  18. Universidad, ciencia y desarrollo: mas allá de la línea base

    Directory of Open Access Journals (Sweden)

    Orlando Pulido Chaves

    1996-04-01

    Full Text Available Este artículo plantea la hipótesis de que la actual crisis a escala global es producto de un cambio en el modelo de desarrollo del capitalismo, consistente en una transformación sustancial de los procesos productivos, y de la transición hacia una nueva fase del capitalismo, caracterizada por el hecho de que las hegemonías y las supremacías se empiezan a construir con base en el predominio del desarrollo científico y tecnológico. Esta crisis expresa el agotamiento del modelo fordista-taylorista, sustentado en la gran industria y en el control del mercado mundial de bienes manufacturados y de capital, y la aparición de tendencias postfordistas, caracterizadas por la lucha por el control del mercado de servicios y de bienes de alta densidad tecnológica, en el que la producción de conocimiento domina las relaciones comerciales.. En este contexto, la universidad, la educación y la investigación cobran importancia estratégica, y plantean retos decisivos para el futuro de los países subdesarrollados.

  19. Bestimmung der Mas'se des neutralen Bs-Mesons mit dem ALEPH-Experiment

    CERN Document Server

    Stehle, M

    2001-01-01

    Gegenstand der vorliegenden Arbeit ist die Bestimmung der Masse des neutralen Bs-Mesons. Dazu wurden B~-Mesonen in den beiden Zerfallskanalen B~ -+ J/W P und B~ -+ W(2S) P rekonstruiert, wobei die Subresonanzen in den Zerfallsmoden J /w -+ l+ l-, W(2S) -+ l+ l- und P -+ K+ K- untersucht wurden. Diese beiden Kanale werden auf Grund ihrer eindeutigen Signatur auch als "goldene Kanale" bezeichnet und eignen sich deshalb sehr gut fur eine exklusive Rekonstruktion, wie sie hier angewendet wurde. Grundlage der Analyse waren ca. 4 Millionen hadronische ZO-Zerfalle, die in den Jahren 1991 1995 mit dem ALEPH-Detektor am e+e--Speicherring LEP am CERN aufgezeichnet wurden. Die zwischenzeitliche Reprozessierung der Daten ermoglichte eine prazisere und effizientere Rekonstruktion als das in fruheren Messungen der Fall war. Wegen der niedrigen Verzweigungsverhaltnisse der untersuchten Zerfallsmoden wurden nur wenige einzelne Ereignisse in den Daten erwartet. Die selektierten Kandidaten wurden durch Schnitte in mehreren Ere...

  20. International Taxation and the Direction and Volume of Cross-Border M&As

    OpenAIRE

    Huizinga, Harry; Voget, Johannes

    2006-01-01

    In an international merger or acquisition, the national residences of the acquirer and the target determine to what extent the newly created multinational firm is subject to international double taxation. This paper presents evidence that the parent-subsidiary structure of newly created multinational firms reflects the prospect of international double taxation. The number of acquiring firms at the national level similarly reflects international double taxation. The evidence suggests that tax ...

  1. The Impact of M&As on the Romanian Banking System – an Event Study Approach

    Directory of Open Access Journals (Sweden)

    Mihaela BRODOCIANU

    2016-12-01

    Full Text Available The study aims to identify the relationship between the merger announcement, the stock prices and the market efficiency. Given the limited data, the analysis has been applied to only one financial institution which merged recently, Banca Transilvania. The results have shown that in the window period, abnormal returns have been identified as the news of the mergers was linked to the press. It can be concluded that the market reaction was positive not till after the official announcement was made. Overall, the acquisitions can be considered as a value added determinant, creating wealth.

  2. Demonstrating multi-layered MAS in control of offshore oil and gas production

    DEFF Research Database (Denmark)

    Lindegaard Mikkelsen, Lars; Næumann, J. R.; Demazeau, Y.

    2013-01-01

    From a control perspective, offshore oil and gas production is very challenging due to the many and potentially conflicting production objectives that arise from the intrinsic complexity of the oil and gas domain. In this paper, we demonstrate how a multi-layered multi-agent system can be used in...

  3. Genome sequence of the moderately thermophilic halophile Flexistipes sinusarabici strain (MAS10T)

    Energy Technology Data Exchange (ETDEWEB)

    Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Chertkov, Olga [Los Alamos National Laboratory (LANL); Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Hammon, Nancy [U.S. Department of Energy, Joint Genome Institute; Deshpande, Shweta [U.S. Department of Energy, Joint Genome Institute; Cheng, Jan-Fang [U.S. Department of Energy, Joint Genome Institute; Tapia, Roxanne [Los Alamos National Laboratory (LANL); Han, Cliff [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Liolios, Konstantinos [U.S. Department of Energy, Joint Genome Institute; Pagani, Ioanna [U.S. Department of Energy, Joint Genome Institute; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Huntemann, Marcel [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Mikhailova, Natalia [U.S. Department of Energy, Joint Genome Institute; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [U.S. Department of Energy, Joint Genome Institute; Palaniappan, Krishna [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Hauser, Loren John [ORNL; Brambilla, Evelyne-Marie [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Rohde, Manfred [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Abt, Birte [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Spring, Stefan [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Bristow, James [U.S. Department of Energy, Joint Genome Institute; Eisen, Jonathan [U.S. Department of Energy, Joint Genome Institute; Markowitz, Victor [U.S. Department of Energy, Joint Genome Institute; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Woyke, Tanja [U.S. Department of Energy, Joint Genome Institute

    2011-01-01

    Flexistipes sinusarabici Fiala et al. 2000 is the type species of the genus Flexistipes in the fami- ly Deferribacteraceae. The species is of interest because of its isolated phylogenetic location in a genomically under-characterized region of the tree of life, and because of its origin from a multiply extreme environment; the Atlantis Deep brines of the Red Sea, where it had to struggle with high temperatures, high salinity, and a high concentrations of heavy metals. This is the fourth completed genome sequence to be published of a type strain of the family Deferribacteraceae. The 2,526,590 bp long genome with its 2,346 protein-coding and 53 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

  4. Marker-assisted-selection (MAS): A fast track to increase genetic ...

    African Journals Online (AJOL)

    Administrator

    2011-09-21

    Sep 21, 2011 ... phenotypic selection of superior individuals among segregating progenies resulting from hybridization. It is often time consuming as breeding a ..... markers used to verify interspecific hybridization between Hemlock. (Tsuga) species. J. Am. Soc. Horticult. Sci., 127: 623-627. Quiros CF (2001). DNA-based ...

  5. Technology enhanced learning for people with intellectual disabilities and cerebral parallysis: the MAS platform.

    OpenAIRE

    Colomo-Palacios, Ricardo; Paniagua-Martín, Fernando; García-Crespo, Ángel; Ruiz-Mezcua, Belén

    2010-01-01

    Proceedings of: First International Conference on Reforming Education, Quality of Teaching and Technology-Enhanced Learning: Learning Technologies, Quality of Education, Educational Systems, Evaluation, Pedagogies (TECH-EDUCATION 2010), Athens, Greece, May, 19-21, 2010 Education for students with disabilities now takes place in a wide range of settings, thus, including a wider range of assistive tools. As a result of this, one of the most interesting application domains of technology enhan...

  6. Cholesterol metabolism: increasingly complex; El metabolismo del colesterol: cada vez mas complejo

    Energy Technology Data Exchange (ETDEWEB)

    Sanhueza, J.; Valenzuela, R.; Valenzuela, A.

    2012-07-01

    Cholesterol is an important molecule; it is necessary for the biosynthesis of steroidal hormones, bile salts and to maintain the stability of biological membranes in animal cells. However, its excess is negative and is responsible for the development of many diseases involving the heart and brain, or in the generation of some types of cancer. For these reasons, the cellular cholesterol levels must be finely regulated and therefore, an infinite number of mechanisms participate in this regulation, which undertake the organism as a whole. These mechanisms should begin to operate efficiently from the intake of cholesterol from the diet, its incorporation into the enterocytes, where are involved carriers such as ABC and NCP1 transporters, PDZ structural motif, to name a few. It is also necessary an adequate regulation of circulating cholesterol and once inside the body, there should be a perfect harmony between the addition of cholesterol to various tissues, its metabolic use, the mechanisms of its tissue deposition, and the synthesis of this lipid. From this perspective, this review offers a general view of the molecular mechanisms that allow the regulation of extra and intracellular cholesterol levels. (Author) 82 refs.

  7. Tropospheric Aerosol Radiative Forcing Observational Experiment (TARFOX) MODIS Airborne Simulator (MAS) Level-1B Data Products

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Tropospheric Aerosol Radiative ForcingObservational Experiment (TARFOX) was to Determine the directradiative impact and (chemical, physical,...

  8. Managing the Evolution of an Enterprise Architecture using a MAS-Product-Line Approach

    Science.gov (United States)

    Pena, Joaquin; Hinchey, Michael G.; Resinas, manuel; Sterritt, Roy; Rash, James L.

    2006-01-01

    We view an evolutionary system ns being n software product line. The core architecture is the unchanging part of the system, and each version of the system may be viewed as a product from the product line. Each "product" may be described as the core architecture with sonre agent-based additions. The result is a multiagent system software product line. We describe an approach to such n Software Product Line-based approach using the MaCMAS Agent-Oriented nzethoclology. The approach scales to enterprise nrchitectures as a multiagent system is an approprinre means of representing a changing enterprise nrchitectclre nnd the inferaction between components in it.

  9. Heterodoxos, mas atuais: um diálogo entre Winnicott e Groddeck

    Directory of Open Access Journals (Sweden)

    Lucas Nápoli dos Santos

    2013-12-01

    Full Text Available The aim of this paper is to establish some points of contact between the thought of Georg Groddeck and Donald Woods Winnicott. To this end, it was conducted a theoretical and conceptual study based in the texts of both authors and commentators. The hypothesis underlying this research is that the dialogue between these authors is an undertaking not only possible but also fruitful. It appears that (1 both authors admit body and psyche as dimensions of the same reality and not as two different essences, (2 perceive the illness as a way to return to earlier stages of development and (3 see nature as a living force and directed to health. Such points of confluence between the authors meet the new demands for reform of the modes of assistance and health care that are emerging from the perception of exhaustion of the traditional medical model organicist (biomedicine.

  10. Formal Social Norms and their Enforcement in Computational MAS by Automated Reasoning

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman; Kazík, O.

    2012-01-01

    Roč. 39, č. 1 (2012), s. 80-87 ISSN 1819-9224 Institutional support: RVO:67985807 Keywords : role model * description logic * integrity constraints * computational intelligence Subject RIV: IN - Informatics, Computer Science

  11. Una etiqueta de plomo con fitónimos procedente de Mas Vell : (Vallmoll, ager Tarraconensis

    Directory of Open Access Journals (Sweden)

    Diana Gorostidi Pi

    2012-01-01

    Full Text Available Presentación de una nueva etiqueta de plomo hallada casualmente en una zona rural del ager Tarraconensis. La pieza presenta dos líneas de texto en las que se ha podido reconocer la presencia de dos fitónimos. La placa está provista de un apéndice lateral en el que se sitúa el agujero para el hilo o cuerda que la unía a la vasija o contenedor. Este elemento resulta muy poco usual en este tipo de documentos epigráficos.A new lead label has been found by chance in a rural area of the ager Tarraconensis. The piece has two writing lines with two plant names. The plate is provided with a lateral appendix with a hole for the filament that connected it to the vessel or box. This element is very unusual in this type of epigraphic documents.

  12. Selected cultivars of cornelian cherry (Cornus mas L.) as a new food ...

    African Journals Online (AJOL)

    STORAGESEVER

    It is a tall deciduous shrub or small tree from. 5 to 8 m high. This plant is popular in southern Europe ... Each parameter was measured in five replications from the fruit taken from each tree of particular cultivars (n = 25). ... species, the absorption disappears (Thaipong et al., 2006). In both methods the calculated activity was ...

  13. The opportunity to build a smarter world; La oportunidad de construir un mundo mas inteligente

    Energy Technology Data Exchange (ETDEWEB)

    Zufiria, J. A.

    2010-07-01

    2010 marks the beginning of the Decade of Intelligence a period characterized by the efficient use of technologies and in which decision-making to build a smarter world will have a key role. At IBM, were convinced its possible to tackle the current challenges, by introducing intelligence into each and every systems and processes. Using new technologies, its possible to make progress in the development of more intelligent solutions and, in fact, many of our customers world-wide are already starting intense innovation and transformation processes, in this regard. (Author)

  14. Industrial Safety. MAS-123. Waste Isolation Division (WID). Management and Supervisor Training (MAST) Program.

    Science.gov (United States)

    Westinghouse Electric Corp., Carlsbad, NM.

    This learning module, which is part of a management and supervisor training program for managers and supervisors employed at the Department of Energy's Waste Isolation Division, is designed to prepare trainees to promote and monitor the industrial safety program at their plant. The following topics are covered in the module's individual sections:…

  15. Encefalopatía neonatal. algo mas que asfixia al nacer

    OpenAIRE

    Cifuentes C., Yolanda; Bermúdez, Martha; Arteaga, Clara

    2011-01-01

    La hiperglicinemia no cetósica (HGNC) es un error innatodel metabolismo, de carácter recesivo, debido a un defectoen el sistema de clivaje, que ocasiona acumulaciónde glicina en la sangre y en el sistema nervioso central,donde activa dos receptores diferentes. El receptor localizadoen la médula espinal, inhibitorio, provoca la apneay el hipo de estos pacientes. El receptor cortical,excitatorio, produce la lesión cerebral y las convulsiones.Se presenta la historia de un recién nacido masculino...

  16. Charge-density study on layered oxyarsenides (LaO)MAs (M = Mn, Fe, Ni, Zn)

    Science.gov (United States)

    Takase, Kouichi; Hiramoto, Shozo; Fukushima, Tetsuya; Sato, Kazunori; Moriyoshi, Chikako; Kuroiwa, Yoshihiro

    2017-12-01

    Using synchrotron X-ray powder diffraction, we investigate the charge-density distributions of the layered oxypnictides (LaO)MnAs, (LaO)FeAs, (LaO)NiAs, and (LaO)ZnAs, which are an antiferromagnetic semiconductor, a parent material of an iron-based superconductor, a low-temperature superconductor, and a non-magnetic semiconductor, respectively. For the metallic samples, clear charge densities are observed in both the transition-metal pnictide layers and the rare-earth-oxide layers. However, in the semiconducting samples, there is no finite charge density between the transition-metal element and As. These differences in charge density reflect differences in physical properties. First-principles calculations using density functional theory reproduce the experimental results reasonably well.

  17. SOMOS O QUE FAZEMOS, MAS SOMOS PRINCIPALMENTE, O QUE FAZEMOS PARA MUDAR O QUE SOMOS

    Directory of Open Access Journals (Sweden)

    Dalmo Valério Machado De Lima

    2011-07-01

    Full Text Available Ao longo da história, o homem sempre procurou justificar suas ações individuais ou coletivas com base naquilo que poderia ser revertido para o próprio indivíduo ou classe. Nessa esteira, a discussão sobre o conceito e aplicabilidade do conhecimento renderia um debate que transcende os fins a que se destina esse editorial. A fim de demarcar uma linha do tempo e de pensamento ao longo da construção que ora se apresenta não se pode deixar de tomar como referência basilar o grego Platão, para quem o conhecimento consiste de crença verdadeira e justificada. Posteriormente, revendo e aprofundando as lições de seu mestre, Aristóteles desmembra o conhecimento em três áreas: científica, prática e técnica. Na Idade Média, o bom frade Roger Bacon, o maior prócer do chamado empirismo aristotélico, estabeleceu as bases de um tipo de investigação científica ainda hoje vigente centrada no esquema da tentativa e do erro, além de, em suas "horas vagas", travestir-se de propagandista dos "benéficos" efeitos do uso da pólvora no trato dos problemas internos e externos de um reino ou feudo.  Com o surgimento da ciência moderna, entre os séculos XVI e XVII, um período denominado Revolução Científica, sedimentam-se e proliferam as ideias de Isaac Newton, Galileu Galilei, René Descartes, Francis Bacon, Nicolau Copérnico, Louis Pasteur e Francesco Redi entre outros, que, reorganizando o pensamento científico, apontam para um campo novo de conhecimento científico cujas implicações são sentidas até os dias de hoje.

  18. CALL Evaluation: Students' Perception and Use of LoMasTv

    Science.gov (United States)

    Pardo-Ballester, Cristina

    2012-01-01

    In order to integrate technology into the language curriculum, it is essential not only to evaluate a program within a second language acquisition (SLA) framework but also to seek the students' attitudes towards the use of computer-assisted language learning (CALL) materials. Guided by Chapelle's (2001) framework for CALL evaluation, this paper…

  19. Introduction Koç Çalışması

    African Journals Online (AJOL)

    Umut Cirit

    While a significant positive correlation was found at seven and eight months of age between all testicular measurements and ... to focus more on the female side with much less emphasis on the male side. However, male ... growth, spermatological traits and serum testosterone levels in growing ram lambs. Materials and ...

  20. Tecnologias mas nuevas para la seguridad escolar (Newer Technologies for School Security). ERIC Digest.

    Science.gov (United States)

    Schneider, Tod

    This digest in Spanish describes several technologies that can be used to control access to, and improve surveillance of, school grounds. Access can be controlled by using "smart" cards to control keyed entries. Many schools have problems with multiple copies of keys, and these card systems are integrated with computer software that…

  1. Ammonia Vapor Removal by Cu3(BTC)2 and Its Characterization by MAS NMR

    Science.gov (United States)

    2009-01-01

    further confirmation of these assignments, Soxhlet - extracted (MeOH) Cu3(BTC)2 is totally devoid of both DMF peaks, leaving only the pristine methine...recoupling to obtain unambiguous assignments of the paramagnetically shifted peaks in Cu(alanine)2(H2O). This method was also applied to Cu3(BTC)2, where

  2. Mergers and Acquisitions (M&AS by R&D Intensive Firms

    Directory of Open Access Journals (Sweden)

    Shantanu Dutta

    2009-12-01

    Full Text Available In this study, we evaluate the impact of R&D intensity on acquiring firms’ abnormal returns by examining 925 Canadian completed deals between 1993 and 2002 that have information on R&D expenditures. While examining the returns to acquiring firm shareholders in the R&D intensive firms we evaluate two competing hypotheses: ‘growth potential hypothesis’ and ‘integration failure hypothesis’. According to the ‘growth potential hypothesis’, in light of the growth potential of the targets acquired by R&D intensive firms, investors are likely to react positively. ‘Integration failure hypothesis’ focuses on integration difficulties of a target by an R&D intensive firms and suggests that investor might be skeptical of such acquisitions and react negatively. Our results show that R&D intensity (i.e. R&D expenditure by sales has a positive and significant effect on cumulative abnormal returns of the acquiring firms around the announcement dates. This implies that market generally favors the M&A deals by R&D intensive firms. An analysis of the differentiating characteristics reveal that R&D firms have a significantly higher growth potential and undertake more stock financed deals compared to the non R&D firms. Further, our results show that there is no significant change in long-term operating performance subsequent to the M&A deals for both R&D firms and non R&D firms. In general, our results show support for ‘growth potential hypothesis’.

  3. Colegios mas seguros a traves del diseno del medioambiente (Safer Schools through Environmental Design). ERIC Digest.

    Science.gov (United States)

    Schneider, Tod

    This digest in Spanish describes the key elements of Crime Prevention Through Environmental Design (CPTED). CPTED is based on the recognition that the physical environment influences human behavior. It is different from conventional security measures, which many times are based on prohibitions, in that it focuses on desired behaviors and attempts…

  4. DAYA MAKAN, DIAPAUSE DAN MOBILITAS KEONG MAS (POMACEA CANALICULATA PADA BERBAGAI KEDALAMAN AIR

    Directory of Open Access Journals (Sweden)

    Jacqualine Arriani Bunga

    2017-04-01

    Full Text Available Feeding rate, aestivation and mobility of golden snails (Pomacea canaliculata at different depths of water. The research was studied in Malaka District, East Nusa Tenggara Province, during the dry and the rainy season (October 2014 - March 2015. Studies on capacity of damage to the Ciherang rice seedlings were carried out for three weeks. The size of snails used in this experiment was 11-20; 21-30; and 31-40 mm. The numbers of seedlings that were planted were 3, 6, 9, 12, 15, 18 and 21 seeds. The treatments were repeated 5 times. The numbers of seeds which are damaged by the snails then were tabulated and analyzed. Snails with the size of 11-20 mm damaged the seeds in 31.67%, followed by snails with the size of 21-30 mm and 31- 40 mm with potency of damaging were 64.76% and 97.38%, respectively. The size of snails affects the level of damage to rice seedlings when transplanting. Study about aestivation was conducted in five villages, namely Kamanasa, Wehali, Umakatahan, Harekakae and Kletek when the rice fields were fallow. The observation point was observed at the corner of the dike and along the dike, evaluated every 10 meters away. The results showed snails aestivate when the fields were dry. Studies on snail’s mobility conducted on the experiment arena on the mud in buckets, which planted with 20 paddy seedlings. The treatment depth of puddles in the experiment were without puddles, half, the same height and twice the height of snails shell. The treatments were repeated 10 times. Measurement of snail’s mobility was performed routinely every 2 hours, observed from the beginning when the snails were placed for 24 hours in advance. The results showed that the depth of the water significantly affected the mobility of snails. Without puddles, the mobility of snails was severely hampered in the mud. The mobility of the juvenile was significantly higher than the imago. The implication of this study was benefit to that the regulating the level of water in the paddy field which is known as an appropriate effective technology and for controlling the attack of the golden snails.

  5. Templo masónico Warwickshire en Edgbaston - Gran Bretaña

    Directory of Open Access Journals (Sweden)

    John Madin, Oficina de Proyectos

    1973-03-01

    Full Text Available The new building, which replaces the old one used for the same purpose, is made up of: — The main temple and its dining room. — Seven assembly rooms, with their corresponding dining rooms. — Hall, made up of: dance room; dining room, and ancillary facilities. — Provincial management offices. — Suite for outstanding personalities. — Kitchens, toilets and cloakrooms. — Car park on the site. The building is made of resistant walls of two-face finished brick, made specially for this building, combined on the outside with precast finished concrete components. Its predominating feature is the almost complete lack of windows in the two floors which make it up. Horizontal communications are around an inner hall, and vertical ones through isolated staircases. The whole temple is air-conditioned and artificially lit, the latter being part of the air-conditioning extraction system.La nueva construcción, que sustituye a otra antigua de igual uso, está constituida por: El templo principal y su comedor. Siete salones con sus correspondientes comedores. Salón de festejos, compuesto por: — sala de baile; — comedor, y — servicios auxiliares. Oficinas del administrativo provincial. Suite para personas muy distinguidas. Servicios de cocina, aseos y guardarropa. Aparcamiento en el interior del solar. El edificio está realizado a base de muros resistentes de ladrillo visto a dos caras, fabricado especialmente para esta construcción, combinado en el exterior con elementos prefabricados de hormigón visto. Su característica dominante es la casi total ausencia de ventanas en las dos plantas de que consta. Las comunicaciones horizontales se desarrollan alrededor de un hall interior, y las verticales mediante escaleras aisladas. La totalidad del templo cuenta con servicios de aire acondicionado e iluminación artificial, integrada esta última en el sistema de extracción del aire acondicionado.

  6. Video Movement Analysis Using Smartphones (ViMAS): A Pilot Study.

    Science.gov (United States)

    Finkbiner, Monica J; Gaina, Kira M; McRandall, Marie C; Wolf, Megan M; Pardo, Vicky M; Reid, Kristina; Adams, Brian; Galen, Sujay S

    2017-03-14

    The use of smartphones in clinical practice is steadily increasing with the availability of low cost/freely available "apps" that could be used to assess human gait. The primary aim of this manuscript is to test the concurrent validity of kinematic measures recorded by a smartphone application in comparison to a 3D motion capture system in the sagittal plane. The secondary aim was to develop a protocol for clinicians on the set up of the smartphone camera for video movement analysis. The sagittal plane knee angle was measured during heel strike and toe off events using the smart phone app and a 3D motion-capture system in 32 healthy subjects. Three trials were performed at near (2-m) and far (4-m) smartphone camera distances. The order of the distances was randomized. Regression analysis was performed to estimate the height of the camera based on either the subject's height or leg length. Absolute measurement errors were least during toe off (3.12 ± 5.44 degrees) compared to heel strike (5.81 ± 5.26 degrees). There were significant (p 0.05) differences between the absolute measurement errors between the two camera positions. The measurement errors averaged between 3 - 5 degrees during toe off and heel strike events of the gait cycle. The use of smartphone apps can be a useful tool in the clinic for performing gait or human movement analysis. Further studies are needed to establish the accuracy in measuring movements of the upper extremity and trunk.

  7. DEVELOPMENT OF FUSARIUM DISEASE CONTROL TECHNOLOGY WITH BIOLOGICAL AGENT IN MAS CULTIVAR BANANA IN LAND INFECTED

    Directory of Open Access Journals (Sweden)

    Anis Shofiyani

    2014-12-01

    Full Text Available Based on the data of General Director of Production and Horticulture, the damage of plantation areas in banana plantation centers in Indonesia always increases in years, this is due to Fusarium attack caused by fungus Fusarium oxisphorum and causing damage of 30- 70 % banana plantation areas.The aim of this empirically for due to biological control technology Fusarium wilt effective and environmentally friendly to the infected area in District Baturaden, Banyumas through soil solarization treatments and utilization of biological agents..The Research was conducted at the wilt disease endemic Fusarium land located in the village Pamijen, District Baturraden, Banyumas. The research design was a Split Plot Design consisting of 2 treatments, the main plot treatments is soil solarization, whereas treatment subplot is the type and dose of biological agents antagonist. The results showed that the treatment given soil solarization proved to increase the temperature of the surface of the soil up to 8.8 ° C compared with without solarization and reduces demand Fussarium population at ground level up to 53.61%, whereas without solarization Fussarium population decline by 22, 33%. Provision of biological agents Trichoderma, Gliocladium and P. Fluoroscens during the study proved to provide inhibition of the development of Fussarium on seedling disease, indicated by the appearance of symptoms of the disease until the end of the study. This is possible due to the formation of phenolic compounds such as tannins, saponins and glicosida and colonization between biological agents with the root system of plants in which the contact between pathogen inhibition with banana plant seedlings root system so that it protects the roots of the disease-causing pathogen infection Fussarium wilt. Treatment of biological agents proved capable of providing better vegetative growth when compared to the untreated biological agents (control in which had significant effect on the number of root parameters, but had no significant effect on plant height parameter, number of leave’s, and stem’s diameter. However, the provision of Trichoderma 100 g / planting hole showed the best results in almost all plant vegetative growth parameters at the end of the reseach.

  8. Selected cultivars of cornelian cherry (Cornus mas L.) as a new food ...

    African Journals Online (AJOL)

    STORAGESEVER

    in the visible region of the electromagnetic spectrum (600-750 nm); this solution is green and its antioxidant activity can be easily measured by means of spectrophotometry. DPPH (2,2-diphenyl-1- picrylhydrazyl) radical scavenging assay was carried out according to the method of Brand-Williams et al. (1995). This test is ...

  9. Location of Chemisorbed Methylium Ions in Zeolites by Neutron Diffraction and 13C MAS NMR

    Czech Academy of Sciences Publication Activity Database

    Vratislav, S.; Dlouhá, M.; Bosáček, Vladimír

    2002-01-01

    Roč. 74, Suppl. (2002), s. S1320-S1322 ISSN 0947-8396 R&D Projects: GA ČR GA202/00/1427 Institutional research plan: CEZ:AV0Z4040901 Keywords : zeolites * neutron diffraction * chemisorbed methyl Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.231, year: 2002

  10. A Quantum Approach to Multi-Agent Systems (MAS), Organizations, and Control

    Science.gov (United States)

    2003-06-01

    Rosenblatt, A., Greenberg, J., Solomon, S., Pyszczynski, T., & Lyon, D. (1990). "Evidence for terror management theroy ." J Personality Social Psychology...Jun 17, 2003, NDU-DC Quantum Perturbation Theory Organization Dissonant Information I generation Endogenous I = new defenses,strategies Exogenous I...new weapons,strategies After perturbations, an organization uses endogenous feedback to defend itself. A competitor uses exogenous feedback to

  11. Classification of astrocyto-mas and meningiomas using statistical discriminant analysis on MRI data

    International Nuclear Information System (INIS)

    Siromoney, Anna; Prasad, G.N.S.; Raghuram, Lakshminarayan; Korah, Ipeson; Siromoney, Arul; Chandrasekaran, R.

    2001-01-01

    The objective of this study was to investigate the usefulness of Multivariate Discriminant Analysis for classifying two groups of primary brain tumours, astrocytomas and meningiomas, from Magnetic Resonance Images. Discriminant analysis is a multivariate technique concerned with separating distinct sets of objects and with allocating new objects to previously defined groups. Allocation or classification rules are usually developed from learning examples in a supervised learning environment. Data from signal intensity measurements in the multiple scan performed on each patient in routine clinical scanning was analysed using Fisher's Classification, which is one method of discriminant analysis

  12. O ensino técnico: : um subsistema inovador mas marginal

    Directory of Open Access Journals (Sweden)

    Helena Vieira

    2015-06-01

    Full Text Available This article, from the perspective of History school subject, seeks to show how technical education was an innovative but marginalized subsystem face to his fellow of the secondary education, the high school. During the New State, the temporal scope of this article, technical education proved to be attentive to the latest pedagogical and didactic currents and sought, particularly from 1948, to educate more citizens than simple workers. However, it continued to be seen as the teaching of others and for the children of others. In order to show the innovative character of technical education and their marginalization in relation to high schools, this article was based on the pedagogical press of the time, particularly in the magazines Labor and Boletim Escolas Técnicas highlighting educational practices developed in History school subject in this two subsystems of education.

  13. Red coralline algae assessed as marine pH proxies using 11B MAS NMR

    Science.gov (United States)

    Cusack, M.; Kamenos, N. A.; Rollion-Bard, C.; Tricot, G.

    2015-01-01

    Reconstructing pH from biogenic carbonates using boron isotopic compositions relies on the assumption that only borate, and no boric acid, is present. Red coralline algae are frequently used in palaeoenvironmental reconstruction due to their widespread distribution and regular banding frequency. Prior to undertaking pH reconstructions using red coralline algae we tested the boron composition of the red coralline alga Lithothamnion glaciale using high field NMR. In bulk analysed samples, thirty percent of boron was present as boric acid. We suggest that prior to reconstructing pH using coralline algae 1) species-specific boron compositions and 2) within-skeleton special distributions of boron are determined for multiple species. This will enable site selective boron analyses to be conducted validating coralline algae as palaeo-pH proxies based on boron isotopic compositions. PMID:25640229

  14. PENGARUH VARIASI KONSENTRASI EKSTRAK SERAI (Andropogon nardus TERHADAP MORTALITAS HAMA KEONG MAS (Pomaceacaniculata L.

    Directory of Open Access Journals (Sweden)

    Sang Putra

    2016-05-01

    Full Text Available Snails (Pomaceae canaliculata L or often referred to as snail mulberry is one type of freshwater snail that comes from the Americas. The spread of snails (Pomaceae canaliculata L. in Indonesia the spread widening due to breeding very fast. Besides, many snails are farmed in ponds so many move to the rice fields. Potential snails can cause crop damage ranges from 10-40%. The aim of this study was to determine the concentration of extract of lemon grass (Andropogon nardus most appropriate for mortalty pest snails (Pomacea caniculata L.. This study was conducted in July to September 2014 in Biology Laboratorium State Islamic Institute (IAIN Raden Intan Lampung. This type of research is experimental. The method used in the study is the method of full randomized design (CRD with three repetitions each cup contains 12 heads snails. The concentration of treatment were 0% (as a control, 2%, 3%, 4%, 5%. Based on the results of the study showed that:The concentration of the most effective in killing pests snails Pomacea caniculata L is 5%, which is able to kill 100% of pest snails Pomacea caniculata L for 24 hours. Sitronela compounds have the nature of a contact poison that can cause death due to loss of fluid continuously.Kata kunci: Mortalitas, ekstrak, kontak racun.

  15. Accelerating proton spin diffusion in perdeuterated proteins at 100 kHz MAS

    Energy Technology Data Exchange (ETDEWEB)

    Wittmann, Johannes J.; Agarwal, Vipin; Hellwagner, Johannes; Lends, Alons; Cadalbert, Riccardo; Meier, Beat H., E-mail: beme@ethz.ch; Ernst, Matthias, E-mail: maer@ethz.ch [ETH Zurich, Physical Chemistry (Switzerland)

    2016-12-15

    Fast magic-angle spinning (>60 kHz) has many advantages but makes spin-diffusion-type proton–proton long-range polarization transfer inefficient and highly dependent on chemical-shift offset. Using 100%-HN-[{sup 2}H,{sup 13}C,{sup 15}N]-ubiquitin as a model substance, we quantify the influence of the chemical-shift difference on the spin diffusion between proton spins and compare two experiments which lead to an improved chemical-shift compensation of the transfer: rotating-frame spin diffusion and a new experiment, reverse amplitude-modulated MIRROR. Both approaches enable broadband spin diffusion, but the application of the first variant is limited due to fast spin relaxation in the rotating frame. The reverse MIRROR experiment, in contrast, is a promising candidate for the determination of structurally relevant distance restraints. The applied tailored rf-irradiation schemes allow full control over the range of recoupled chemical shifts and efficiently drive spin diffusion. Here, the relevant relaxation time is the larger longitudinal relaxation time, which leads to a higher signal-to-noise ratio in the spectra.

  16. Structural characteristics of marine sedimentary humic acids by CP/MAS sup(13)C NMR spectroscopy

    Digital Repository Service at National Institute of Oceanography (India)

    Sardessai, S.; Wahidullah, S.

    acides humiques de la mer d’Arabie ; les acides humiques des stdiments estuariens et &tiers de la baie du Bengale sont dominks par les hyd.rates de carbone et les structures aro- matiques, ainsi que, dans une moindre mesure, par les structures... ont CtC Ctudiks dans diffkrents environnements de d6pp8ts par RMN du 13C (&at solide) et les rksultats ont Ctt cornparks avec les analyses chimiques traditionnelles en milieu liquide. Les donnkes obte- nues sont en accord avec la littkrature...

  17. A Standards-Based Thematic Unit: "La Mujer Que Brillaba Aun Mas Que el Sol"

    Science.gov (United States)

    Bullitt, Leslie Kay; Gonzalez, Augusta C.; Luna, Boni

    1998-01-01

    This unit was created as a result of a summer institute sponsored by the National K-12 Foreign Language Resource Center at Iowa State University, Ames, Iowa. The Center's goal is to improve student learning of foreign languages in kindergarten through twelfth grade (K-12). To this end, the Center provides professional support for foreign language…

  18. Pengaruh beberapa Jenis Ekstrak Tanaman sebagai Moluskisida Nabati terhadap Keong Mas (Pomacea canaliculata

    Directory of Open Access Journals (Sweden)

    Agus Kardinan

    1997-12-01

    Full Text Available Research has been carried out at the Pest and Disease Laboratory, Research Institute for Spices and Medicinal Crops, Bogar, in the 1997. Research consisted of three parts, those were; (I The toxicity of Dens elliptica, Blumea balsamifera, and methaldehyde, by determining the LC50 values, (2 Effect of the leaves of B.balsamifera, Euphorbia tirucalli and Tephrosia vogelii, (3 Effect of the most poisonous plant as ovicides. Result showed that D.elliptica was the most poisonous material to golden snail with its LC50 value was 400ppm, but it was still under the toxicity value of methaldehyde (11. 78 ppm. There was no significant difference among B.balsamifera, T.vogelii and E. canaliculata, but extract of B.balsarnifera tended to be better material among those plant extracts tested. The extract of D.elliptica did not affect egg hatching of golden snail.

  19. Iridoids from Cornus mas L. and their potential as innovative ingredients in cosmetics

    Directory of Open Access Journals (Sweden)

    Nizioł-Łukaszewska Zofia

    2017-12-01

    Full Text Available Dogwood berries represent a valuable source of a variety of active ingredients. A group that deserves special attention comprises iridoids – compounds with potent antioxidant, antiinflammatory and antibacterial properties. The present study is an attempt to obtain an innovative plant material from dogwood berries. To this end, water and water/ethanol-based extracts (1:1 were prepared and, as the next step, an iridoids-rich fraction was isolated. The total content of iridoids was determined spectrophotometrically, and antioxidant properties of the isolates were concurrently assessed. Additionally, skin whitening activity of isolated fractions was assessed on the basis of tyrosinase inhibition measurement. The testing schedule also involved the formulation of model washing systems based on anionic surfactants. The effect of adding the fractions obtained by the above method on the irritant potential was assessed by determining the zein number

  20. Probing sol-gel matrices microenvironments by PGSE HR-MAS NMR.

    Science.gov (United States)

    Ferreira, Ana S D; Barreiros, Susana; Cabrita, Eurico J

    2017-05-01

    We applied Pulsed Gradient Spin Echo diffusion with high-resolution magic angle spinning NMR to study sol-gel matrices used to encapsulate enzymes for biocatalysis (TMOS/MTMS and TMOS/BTMS) to gain insight into the local chemical microenvironment. Transport properties of solvents with different polarities (1-pentanol, acetonitrile and n-hexane) were studied through their apparent self-diffusion coefficients. The spin echo attenuation of the solvents shows two distinct diffusion domains, one with fast diffusion (D fast ) associated with interparticle diffusion and another with slow diffusion (D slow ) corresponding to the displacement inside the pores within the sol-gel particles. The analysis of the root mean square displacements at different diffusion times showed that the D fast domain has a free diffusion regime in both matrices (the root mean square displacement is linearly dependent of the diffusion time), while the D slow domain shows a different regime that depends on the matrix. We investigated the exchange regime between the two diffusion sites. In both matrices, n-hexane was in intermediate exchange between diffusion domains, while the polar solvents were in slow exchange in TMOS/BTMS and in intermediate exchange in TMOS/MTMS. Data were fitted for TMOS/BTMS with the Kärger model, and the physical parameters were obtained. The results add to the evidence that the pores are a hydrophobic environment but that the presence of some free hydrophilic groups inside the pore, as observed in the TMOS/BTMS, has a key role in slowing down the exchange of polar solvents and that this is relevant to explain previously reported enzyme activity in these materials. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  1. International Taxation and the Direction and Volme of Cross-Border M&As

    NARCIS (Netherlands)

    Huizinga, H.P.; Voget, J.

    2006-01-01

    In an international merger or acquisition, the national residences of the acquirer and the target determine to what extent the newly created multinational firm is subject to international double taxation. This paper presents evidence that the parent-subsidiary structure of newly created

  2. Knowledge plus Attitude in Radiation Protection; Aptitud mas Actitud en Proteccion Radiologica

    Energy Technology Data Exchange (ETDEWEB)

    Velez, G. R.; Sanchez, G. D.

    2003-07-01

    Since the introduction of the Basic Safety Standards recommendations, the scope of the radiation protection was broadening. On behalf of the incorporation of radiation protection of the patient in medical exposures, the different groups of professionals involved: physicians, medical physicists, radiation protection officers, regulators, etc., have to work together. The objective of radiation protection, that is, to reduces doses from practices, to prevent potential exposures, to detect its occurrence as well as to evaluate and spread such abnormal situations, will be obtained only if it were possible to joint two basic conditions: knowledge and attitude. It should be well known the differences between the backgrounds needed to be for example, a medical physicist or an R.P.O., However, their attitude to solve an eventual problem involving radiation protection should be the same; as well as the behavior of the specialized physician and regulators, in order to add towards common goals. In this work, we show as an example the curricula contents about radiation protection of the cancer of medical physics in the Universidad Nacional de San Martin (UNSAM), and the corresponding module on medical exposures from the Post-Graduate course on Radiation Protection and Nuclear Safety, held since the 80s in Buenos Aires by the National Commission of Atomic Energy, ARN, IAEA, and the Universidad de Buenos Aires. On the other hand, we describe different attitudes which leads or could start major radiological accidents, regardless the level of knowledge in radiation protection. We conclude that the larger numbers of accidents are due to problems in the attitude than in the level of knowledge of the person involved. Consequently; we suggest emphasizing the discussion on how to generate positive attitudes in every professional involucrated, independently of its cognitive profile or level. (Author) 2 refs.

  3. Influence of different doses of FitoMas-E on common bean

    Directory of Open Access Journals (Sweden)

    Edelio Guevara Tejeda

    2016-02-01

    Full Text Available This work was developed in the Agricultural Enterprise “Omar Rivero Fonseca”, located in Manzanillo municipality, Granma province, in order to determine the effect of different doses of Fitomas-E on the vegetative growth variables in bean crop. Results showed differential responses in the evaluated variables: stem diameter, fruit length, number of leaves per plant, number of pod and seed number per fruit, depending on the different concentrations of Fitomas-E that were applied. The treatment with 60 mL was the most effective one.

  4. Algo mas sobre la enfermedad y muerte de José Eustasio Rivera

    Directory of Open Access Journals (Sweden)

    Humberto Roselli Quijano

    2003-03-01

    Full Text Available

    José Eustasio Rivera nació en Neiva el 19 de febrero de 1888. Cursó la primaria en el Colegio de Santa Librada en su ciudad natal y el bachillerato en la Escuela Normal de Bogotá.
    Posteriormente estudió derecho en la Universidad Nacional y se graduó de abogado en 1917. En 1921 publicó "Tierra de Promisión", su admirable libro de sonetos y al año siguiente fue designado Secretario
    de la Comisión de Limites con Venezuela; en 1924 publicó La Vorágine y en 1928 fue nombrado delegado de la Conferencia Internacional de Emigración de la Habana. Se trasladó enseguida a Nueva York en donde transcurrieron los últimos meses de su vida, habiendo fallecido el 1 de diciembre de 1928, a las 12:50, a los 40 años y 9 meses de su edad.

    Rivera, por su profesión de abogado, atendía cuantiosos pleitos en los Llanos de Casanare, por lo cual permanecía largas temporadas en Sogamaso, puerta de entrada a Los Llanos, alojándose en la pensión de doña Adriana Camargo de Albarracín o en la quinta de su amigo Lisandro Durán que quedaba en las estribaciones que cierran el valle hacia el noroeste. Con el señor Durán compartían fraternalmente la afición por la cinegética, a la que ambos rendían culto en los cerros que rodean la laguna de Tota.
    Es sabido que Rivera padeció en varias ocasiones crisis de delirio agudo febril con convulsiones en una de las cuales falleció en Nueva York. Otra le había sobrevenido en 1918 en Orocué; luego se le repitió en Sogamaso en 1920 en que fue atendido por el Dr. Julio Sandoval, distinguido médico de la localidad. La crisis se repitió con características de gravedad en Purificación, Tolima, en marzo de 1921...

  5. Product diversification of banana cv. Mas Kirana off grade by using a double rotating screw extruder

    Science.gov (United States)

    Setyadjit, S.; Sukasih, E.; Risfaheri, R.

    2018-01-01

    Extrusion technology is today’s favorite technology since it has a varied, practical and consistent product form. The purpose of this research was to get precise composite flour composition so that the quality of the resulted product has optimum quality for breakfast meals. The experimental design used was Design Expert vs. 7 with response surface box-behnken. The flour composition and level to be inputted to the program were banana flour (10-50g), mung beans (10-30g), egg flour (10-20g). Formula made was based on 200 g with addition of maize flour if the amount is less than 200 g. The extrusion tool used is a Thermo Scientific double rotating screw; with Haake Reomax OS. The best results in terms of carbohydrate content is the Formula 8 with a composition of 60 g of banana flour, 20 g eggs, 20 g of green beans and 100 g maize flour. The proximate chemical content of this formula is carbohydrate 84.04%, protein 8.55%, fat 5.49%, ash content 1.24%. K-calories per 100 g is 419.5 which is higher than the standard of breakfast meals calories.

  6. SOMOS O QUE FAZEMOS, MAS SOMOS PRINCIPALMENTE, O QUE FAZEMOS PARA MUDAR O QUE SOMOS

    OpenAIRE

    Lima, Dalmo Valério Machado De; Universidade Federal Fluminense - UFF

    2011-01-01

    Ao longo da história, o homem sempre procurou justificar suas ações individuais ou coletivas com base naquilo que poderia ser revertido para o próprio indivíduo ou classe. Nessa esteira, a discussão sobre o conceito e aplicabilidade do conhecimento renderia um debate que transcende os fins a que se destina esse editorial. A fim de demarcar uma linha do tempo e de pensamento ao longo da construção que ora se apresenta não se pode deixar de tomar como referência basilar o grego Platão, para...

  7. Anglicismu lietošana franču reklāmas jomā

    OpenAIRE

    Koļesova, Tatjana

    2015-01-01

    Šī pētījuma mērķis ir izpētīt anglicismu lietošanas tendences un faktorus mūsdienu franču reklāmā. Izpēte balstās uz to anglicismu analīzi, kas rodami desmit 2014.gada franču žurnālos. Pētījuma pamatā ir tādu slavenu valodnieku kā Renē Ētjembla, Manfreda Hoflera un Lionela Meneijē teorētiskie darbi, kā arī tādi leksikogrāfijas izdevumi kā lielā terminoloģijas vārdnīca, vārdnīca Larousse, anglicismu vārdnīca «Les usuels du Robert» u.c. Izpētes pamatā ir kvantitatīvā un kvalitatīvā metode. Anal...

  8. Türgi euroliidu ukse taha jäämas / Märt Kivine

    Index Scriptorium Estoniae

    Kivine, Märt, 1967-

    2005-01-01

    Üle-euroopalise küsitluse kohaselt on 52% eurooplastest Türgi EL-iga liitumise vastu. Saksa konservatiivide aseesimehe Wolfgang Schäuble on seisukohal, et EL ei tohi laieneda väljapoole Euroopat, vastasel juhul ei samasta inimesed end enam EL-iga. Diagramm: Enamik Türgi liitumise vastu

  9. Empresa familiar, sim! Mas qual o problema, se a gestão é profissional?

    Directory of Open Access Journals (Sweden)

    Alicelia Rosa de Oliveira Pecanha

    2015-07-01

    Full Text Available Este artigo visa contribuir para melhor compreensão da realidade de uma empresa familiar brasileira em fase de transição do seu modelo de gestão familiar para uma gestão profissionalizada. A empresa estudada é uma livraria brasileira de pequeno porte, fundada em 2000, no interior do estado do Rio de Janeiro, atualmente com seis lojas próprias e outra franqueada, totalizando quarenta funcionários. Sua administração, basicamente familiar, necessita de um novo modelo de gestão para acompanhar o ritmo de sua expansão. O método de pesquisa adotado foi o estudo de caso, com a coleta de dados por meio de entrevistas semiestruturadas com os gestores da empresa. Os principais resultados mostraram que, embora a empresa esteja em processo inicial de profissionalização, precisa, no entanto, acelerar esse processo, adotando uma postura proativa que dê suporte ao seu crescimento.

  10. Central Equatorial Pacific Experiment (CEPEX) MODIS Airborne Simulator (MAS) Level-1B Data Products

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Central Equatorial Pacific Experiment (CEPEX) campaign was to study the effects that Cirrus cloud radiative and surface evaporation properties...

  11. Schémas argumentaux et homonymie : l'exemple de la construction conative en anglais

    Directory of Open Access Journals (Sweden)

    Delhem, Romain

    2015-07-01

    Full Text Available After showing how Construction Grammar (Goldberg 1995 accounts for verb complementation, this contribution studies a problematic argument structure construction of contemporary English: the conative construction, in which a verb is directly followed by an oblique complement in at. In her monograph, Goldberg seems to claim that this argument structure construction has a single abstract meaning that can be found in all its uses: an action directed toward a target. I show that this meaning, given by Goldberg and other authors, not only is too vague, but does not account for all potential instances of this construction. A closer analysis of this construction therefore seems necessary to account for the variations in meaning it exhibits according to the meaning of the verb to which it is associated. The article also shows some limits of Construction Grammar as Goldberg presents it, and suggests that this approach be doubly amended by recognizing both the existence of basic or default argument structure construction for every verb, and the possibility for some argument structure constructions to be homonymic.

  12. A mas de cien años de la muerte de Jose Martí

    OpenAIRE

    Quesada Camacho, Juan Rafael

    2016-01-01

    Desde el momento en que surgieron los Estados Nacionales en América Latina, ha existido una produnfa preocupación por encontrar respuestas a preguntas tales como: ¿Quieres somos?  ¡De dónde venimos?  ¿A dónde queremos ir? 

  13. Plant and Industry Experience. MAS-122. Waste Isolation Division (WID). Management and Supervisor Training (MAST) Program.

    Science.gov (United States)

    Westinghouse Electric Corp., Carlsbad, NM.

    This learning module, which is part of a management and supervisor training program for managers and supervisors employed at the Department of Energy's Waste Isolation Division, is designed to prepare trainees to use plant and industry experience to improve plant safety and reliability. The following topics are covered in the module's individual…

  14. A MAS-Based Cloud Service Brokering System to Respond Security Needs of Cloud Customers

    Directory of Open Access Journals (Sweden)

    Jamal Talbi

    2017-03-01

    Full Text Available Cloud computing is becoming a key factor in computer science and an important technology for many organizations to deliver different types of services. The companies which provide services to customers are called as cloud service providers. The cloud users (CUs increase and require secure, reliable and trustworthy cloud service providers (CSPs from the market. So, it’s a challenge for a new customer to choose the highly secure provider. This paper presents a cloud service brokering system in order to analyze and rank the secured cloud service provider among the available providers list. This model uses an autonomous and flexible agent in multi-agent system (MASs that have an intelligent behavior and suitable tools for helping the brokering system to assess the security risks for the group of cloud providers which make decision of the more secured provider and justify the business needs of users in terms of security and reliability.

  15. Analysis of Hydroperoxides in Solid Polyethylene by MAS (13)C NMR and EPR

    International Nuclear Information System (INIS)

    ASSINK, ROGER A.; CELINA, MATHIAS C.; DUNBAR, TIMOTHY D.; ALAM, TODD M.; CLOUGH, ROGER LEE; GILLEN, KENNETH T.

    1999-01-01

    13 C-enriched polyethylene was subjected to γ-irradiation in the presence of air at 25 and 80 C for total doses ranging from 71 to 355 kGy. Significant quantities of hydroperoxides were detected in the 25 C irradiated sample by 13 C magic angle spinning NMR spectroscopy. This method of detection was performed on the solid polymer and required no chemical derivatization or addition of solvent. The chemical stability and subsequent products of the hydroperoxide species were studied by annealing the irradiated samples in air at temperatures ranging from 22 to 110 C. A time-temperature superposition analysis provided an activation energy of 108 kJ/mol for the hydroperoxide decomposition process. The primary products of hydroperoxide decomposition were ketones and secondary alcohols with lesser amounts of acids and esters. EPR measurements suggest that the reactive hydroperoxide species reside in the amorphous phase of polyethylene, consistent with degradation occurring in the amorphous phase

  16. PENENTUAN TINGKAT TOLERANSI IKAN MAS (Cyprinus carpio L TERHADAP LIMBAH CAIR INDUSTRI SASIRANGAN

    Directory of Open Access Journals (Sweden)

    Elrifadah Elrifadah

    2016-05-01

    Full Text Available Objective of this research were to know the tolerance rate of common carp to liquid waste of sasirangan industries, effect of liquid waste of sasirangan industries to common carp mortality , water quality media, and common carp gills under exposures in 96 hours. Method in this research was Static Bioassay.  Tolerance Limit Media (TLM or Lethal Concentration 50 % (LC50 in 96 hours used to determine of common carp tolerance rate with toxicity test.   Before toxicity test, preliminary test be done for determination of  upper and lower limit concentration. Completely randomize design with 5 treatments and 3 replicates was used in this research.  Application of liquid waste concentration as the treatment was K without liquid waste (0%, A (4,5%, B (5,5%, C (6,5%, and D (7,5%.  The data analyzed by using Analysis of Variance (Anova, and Duncan Multiple Range Test (DMRT.          Result of the research showed that tolerance rate of common carp to liquid waste (LC50-96 hours was in concentration 4,9%.  Mortality rate was 0%; 33,33% and 76,66% for treatment K, A, and B respectively, but for treatment C and D reaches 100 %.    Anova and DMRT result indicated that liquid waste of sasirangan industries had significant effect (P< 0,05 to mortality rate of common carp.  Liquid waste also affect  water quality media such as temperature, pH, BOD, COD, NH3, Zn, and fenol, all of the parameters increasingly, except DO get decrease.  Based of histological analyze, liquid waste had impact to the gills. The  higher the liquid waste concentration makes the higher the damage rate.

  17. Pomological Characteristics of Cornelian Cherry (Cornus mas L. Selections in Serbia and the Possibility of Growing in Intensive Organic Orchards

    Directory of Open Access Journals (Sweden)

    Sandra Bijelić

    2015-01-01

    Full Text Available The Cornelian cherry, which can be used as both food and medicine, is highly tolerant to diseases and pests, so it is a rare plant species that can be grown without chemicals and it is capable of fruit bearing under modest agrotechnical conditions. In Serbia, over 500 Cornelian cherry genotypes have been monitored and observed in all morphological and chemical characteristics and registered a very large variation in flowering time and maturity, morphometric properties of fruits and nutrient content. Based on the last three years results, this paper shows pomological characterization for five the best selections that can be recommended for reproduction by specially developed technology to the Faculty of Agriculture in Novi Sad, and their benefits of growing in organic orchards. Phenological observations showed that the earliest start of flowering was noted for Apatinski rani and R1 (mid-January while later flowering was in Bačka and PPC1 (end of January. At the latest flowering registered in CPC16 (in early February. Although Cornelian cherry flowers early, before leafing, fruits ripen very late. In the average for all study years, the earliest start of ripening fruit was found in PPC1, following Apatinski rani and CPC16 (mid-July while latest start ripe fruit Bačka (in early August. On the basis of morphometric measurements clearly stands out PPC1 from the fruits of maximum mass (6.60 g and flesh ratio (88.75%, followed by R1 (4.55 g; 87.84%. All other genotypes have a weight over 3 g and flesh ratio over than 80%. The average the total soluble solids, total acidity, total sugar, vitamin C and anthocyanins were 20.22%; 2.59%; 16.28%; 19.13 mg/100 g; 87.00 mg/g, respectively, for all examined genotypes.

  18. Mas felicidad para un mayor numero de personas: ¿Es posible esto en México?

    NARCIS (Netherlands)

    R. Veenhoven (Ruut)

    2013-01-01

    textabstract¿Cuál es el objetivo final de las políticas públicas? Jeremy Bentham (1789) diría: mayor felicidad para más personas. Él entendió la felicidad como el goce subjetivo de la vida, es decir "la suma de placeres y dolores". Sin embargo, en su época la felicidad de la población general no

  19. Acidic properties of SSZ-33 and SSZ-35 novel zeolites: a complex infrared and MAS NMR study

    Czech Academy of Sciences Publication Activity Database

    Gil, B.; Zones, S. I.; Hwang, S.-J.; Voláková, Martina; Čejka, Jiří

    2008-01-01

    Roč. 112, č. 8 (2008), s. 2997-3007 ISSN 1932-7447 R&D Projects: GA ČR GA104/07/0383; GA AV ČR 1QS400400560 Institutional research plan: CEZ:AV0Z40400503 Keywords : nuclear magnetic resonance * adsorbed probe molecules * angle- spinning NMR Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.396, year: 2008

  20. Characterizing crystal disorder of trospium chloride: a comprehensive, 13C CP/MAS NMR, DSC, FTIR, and XRPD study

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Martina; Šturcová, Adriana; Brus, Jiří; Beneš, Hynek; Skořepová, E.; Kratochvíl, B.; Čejka, J.; Šeděnková, Ivana; Kobera, Libor; Policianová, Olivia; Šturc, A.

    2013-01-01

    Roč. 102, č. 4 (2013), s. 1235-1248 ISSN 0022-3549 R&D Projects: GA ČR GPP106/11/P426 Institutional support: RVO:61389013 Keywords : trospium chloride * solid state NMR * factor analysis Subject RIV: FR - Pharmacology ; Medidal Chemistry Impact factor: 3.007, year: 2013

  1. Angiotensin-converting enzyme 2, Angiotensin-(1-7) and Mas: new players of the Renin Angiotensin System

    DEFF Research Database (Denmark)

    Santos, Robson AS; Ferreira, Anderson J; Verano-Braga, Thiago

    2013-01-01

    Angiotensin(Ang)-(1-7) is now recognized as a biologically active component of renin-angiotensin system (RAS). Ang-(1-7) appears to play a central role in the RAS because it exerts a vast array of actions, many of them opposite to those attributed to the main effector peptide of the RAS, Ang II. ...

  2. Quase tudo que você queria saber sobre tectônica, mas tinha vergonha de perguntar

    Directory of Open Access Journals (Sweden)

    Izabel Amaral

    2009-12-01

    Full Text Available O termo tectônica não é de uso exclusivo da arquitetura. Sem dúvida, é mais conhecido do grande público em referência à teoria que estuda o movimento das placas continentais no domínio da geologia. Em arquitetura, mesmo que o termo circule cada vez mais nos livros, revistas, websites, blogs e escolas de arquitetura, definir tectônica é tanto mais difícil na medida em que, dada sua presença descontínua ao longo da história, esse termo dificilmente pode ser associado a um único significado. Freqüentemente definida como" arte da construção", uma melhor compreensão da tectônica não pode passar ao lado de uma melhor compreensão da trajetória histórica do termo. Derivada do grego tekton (carpinteiro, a noção atravessou mais de 2000 anos de história. Sua compreensão mudou em relação ao original grego, principalmente devido às contribuições dos teóricos alemães Carl Bötticher e Gottfried Semper no século 19, e, mais recentemente, devido à notável contribuição de Kenneth Frampton (1983, 1990, 1995, 2005. Este último autor provocou uma renovação do debate sobre a tectônica, promovendo a noção ao estatuto de" potencial de expressão construtiva" da arquitetura, capaz de reunir aspectos materiais e construtivos aos aspectos culturais e estéticos. Para entendermos a evolução do conceito de tectônica, este texto se propõe, em um primeiro momento, a traçar sua história, que começaria com uma consciência técnica da física da construção ainda no século 18, para, em seguida, discutir os dois últimos teóricos acima citados e, por fim, levantar algumas das novas perspectivas sobre a atualidade dessa noção.

  3. Proton-detected MAS NMR experiments based on dipolar transfers for backbone assignment of highly deuterated proteins

    Science.gov (United States)

    Chevelkov, Veniamin; Habenstein, Birgit; Loquet, Antoine; Giller, Karin; Becker, Stefan; Lange, Adam

    2014-05-01

    Proton-detected solid-state NMR was applied to a highly deuterated insoluble, non-crystalline biological assembly, the Salmonella typhimurium type iii secretion system (T3SS) needle. Spectra of very high resolution and sensitivity were obtained at a low protonation level of 10-20% at exchangeable amide positions. We developed efficient experimental protocols for resonance assignment tailored for this system and the employed experimental conditions. Using exclusively dipolar-based interspin magnetization transfers, we recorded two sets of 3D spectra allowing for an almost complete backbone resonance assignment of the needle subunit PrgI. The additional information provided by the well-resolved proton dimension revealed the presence of two sets of resonances in the N-terminal helix of PrgI, while in previous studies employing 13C detection only a single set of resonances was observed.

  4. Arctic Radiation Measurement in Column: Atmosphere-Surface (ARMCAS) MODIS Airborne Simulator (MAS) Level-1B Data Products

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Arctic Radiation Measurement in Column: Atmosphere-Surface (ARMCAS) experiment was to detect and differentiate between clouds, ice, and snow...

  5. High resolution MAS 1H NMR spectroscopic analysis of rabbit cornea after treatment with dexamethasone and exposure to UVB radiation

    Czech Academy of Sciences Publication Activity Database

    Seather, O.; Krane, J.; Risa, O.; Čejková, Jitka; Midelfart, A.

    2005-01-01

    Roč. 30, - (2005), s. 1041-1049 ISSN 0271-3683 R&D Projects: GA ČR GA304/03/0419 Institutional research plan: CEZ:AV0Z5008914 Keywords : aqueous humour * cornea Subject RIV: FF - HEENT, Dentistry Impact factor: 1.116, year: 2005

  6. Association analyses of the MAS-QTL data set using grammar, principal components and Bayesian network methodologies

    Directory of Open Access Journals (Sweden)

    Karacaören Burak

    2011-05-01

    Full Text Available Abstract Background It has been shown that if genetic relationships among individuals are not taken into account for genome wide association studies, this may lead to false positives. To address this problem, we used Genome-wide Rapid Association using Mixed Model and Regression and principal component stratification analyses. To account for linkage disequilibrium among the significant markers, principal components loadings obtained from top markers can be included as covariates. Estimation of Bayesian networks may also be useful to investigate linkage disequilibrium among SNPs and their relation with environmental variables. For the quantitative trait we first estimated residuals while taking polygenic effects into account. We then used a single SNP approach to detect the most significant SNPs based on the residuals and applied principal component regression to take linkage disequilibrium among these SNPs into account. For the categorical trait we used principal component stratification methodology to account for background effects. For correction of linkage disequilibrium we used principal component logit regression. Bayesian networks were estimated to investigate relationship among SNPs. Results Using the Genome-wide Rapid Association using Mixed Model and Regression and principal component stratification approach we detected around 100 significant SNPs for the quantitative trait (p Conclusions GRAMMAR could efficiently incorporate the information regarding random genetic effects. Principal component stratification should be cautiously used with stringent multiple hypothesis testing correction to correct for ancestral stratification and association analyses for binary traits when there are systematic genetic effects such as half sib family structures. Bayesian networks are useful to investigate relationships among SNPs and environmental variables.

  7. Datu bāzu un to lietotāju saskarsmes problēmas interneta vidē

    OpenAIRE

    Blekte, Guntars

    2009-01-01

    Tīmekļa vietņu dizaina izveide ir sarežģīts un atbildīgs process, jo būs būtisks faktors, kas noteiks vietnes veiksmīgumu. Dizainerim ir jāņem vēra dažādi lietotāju instinkti, kas ir veidojušies un tiek veidoti, lietotājiem apmeklējot citas tīmekļa vietnes. Šajā darbā autors apskata dažādus tīmekļa vietņu izveides faktorus un pēta kā vietņu dizaina attīstība sasaistās ar datora aplikāciju dizaina attīstību, un kā aplikāciju dizains nosaka kopējo virtuālā dizaina modi. Darba saturā tiek apkopo...

  8. Corpos estranhos, mas não esquecidos: representações de mulheres e homens sobre seus corpos feridos

    Directory of Open Access Journals (Sweden)

    Evanilda Souza de Santana Carvalho

    2013-02-01

    Full Text Available Estudo qualitativo, cujo objetivo foi apreender e analisar as representações sobre o corpo ferido, e em que foram colhidos, através da entrevista em profundidade, depoimentos de dezoito adultos, feridos crônicos, usuários de ambulatório de cuidado a pessoas com feridas de um hospital público na cidade de Salvador-BA. A partir da Análise de Conteúdo Temática, emergiram as seguintes categorias relativas ao corpo ferido: é um estranho que promove sofrimento; é constantemente vigiado; é rejeitado; é prisioneiro; está vulnerável à violência; exige cuidado especial e, é um corpo em luto. Essas representações firmam-se em imagens negativas e de sofrimento, e evidenciam que o corpo ferido, muito diferente do corpo idealizado, promove sentimentos contraditórios e autodepreciativos. Os resultados revelaram que as pessoas com feridas crônicas estranham seus próprios corpos, experimentam sentimentos negativos acerca de sua imagem, e mobilizam alternativas de autocuidado e de apresentação pessoal, distintas das acionadas antes da cronificação.

  9. 'Todo Vagabundo é Maconheiro, mas nem todo Maconheiro é Vagabundo'. Um Estudo com Consumidores Estáveis de Maconha

    OpenAIRE

    LIMA FILHO, F. A.

    2010-01-01

    A maconha é substância psicoativa mais consumida em todo o mundo. A literatura científica sobre maconha enfoca principalmente efeitos farmacológicos ocasionados, estratégias de prevenção, políticas públicas para consumidores de drogas e consumidores abusivos. Apenas um pequeno número de estudos dedica-se a investigar aspectos psicossociais sobre o consumo, assim como valores e práticas de consumidores de maconha socialmente integrados. A partir dessa lacuna, procuramos investigar o consumo de...

  10. Assessment of capabilities in persons with advanced stage of dementia: Validation of The Montessori Assessment System (MAS).

    Science.gov (United States)

    Erkes, Jérôme; Camp, Cameron J; Raffard, Stéphane; Gély-Nargeot And, Marie-Christine; Bayard, Sophie

    2017-01-01

    This study evaluated the validity and reliability of the Montessori Assessment System. The Montessori Assessment System assesses preserved abilities in persons with moderate to severe dementia. In this respect, this instrument provides crucial information for the development of effective person-centered care plans. A total of 196 persons with a diagnosis of dementia in the moderate to severe stages of dementia were recruited in 10 long-term care facilities in France. All participants completed the Montessori Assessment System, the Clinical Dementia Rating Scale and/or the Mini Mental State Examination and the Severe Impairment Battery-short form. The internal consistency and temporal stability of the Montessori Assessment System were high. Additionally, good construct and divergent validity were demonstrated. Factor analysis showed a one-factor structure. The Montessori Assessment System demonstrated satisfactory psychometric properties while being a useful instrument to assess capabilities in persons with advanced stages of dementia and hence to develop person-centered plans of care.

  11. Respon Imun Spesifik Larva Ikan Mas (Cyprinus carpio melalui Imunitas Maternal yang Diberi Vaksin Inaktif Whole Cell Aeromonas salmonicida

    Directory of Open Access Journals (Sweden)

    Syohibahttul Islamiyah BAHAR

    2017-02-01

    Full Text Available Aeromonas salmonicida are specific bacteria that can cause infections and death to the cultivation of carp (Cyprinus carpio during larval stage. Death in carp can be prevented by a vaccine, but the vaccine can only be given on the seed over the age of 3 weeks. Maternal vaccination needs to be done to improve the immune system of the larvae by means of inactivated whole cell vaccine A. salmonicida on broodstock ready to spawn. Aims to determine the effectiveness of vaccines on breeders carp to the parent antibody titer test and larvae, as well Survival Rate (SR and the Relative Percent Survival (RPS larvae. This research was conducted with a completely randomized design, 4 treatments A (control; B (0.3 ml/kg; C (0.4 ml/kg; D (0.5 ml/kg and 3 repetitions. The results show that the antibody titer of 0.3 ml dose capable of providing agglutination reaction to pitting 7th (64x dilution in broodstock, and vaccine doses 0,4ml on broodstock able to give agglutination reaction to the larvae until all 6 wells (32x dilution. A dose of 0.4 ml/kg resulted the highest SR and RPS with 96.11% and 81.25% respectively. Clinical symptoms of redness in control larvae was spread throughout the body whereas on the vaccine treatment was only in certain body parts. Keywords: A. salmonicida, vaccines, maternal immunity, larva, specific immune respon

  12. Seleksi Bakteri Berpotensi Probiotik dari Ikan Mas (Cyprinus Carpio Indegenous Jantho Berdasarkan Aktivitas Antibakteri secara In Vitro

    Directory of Open Access Journals (Sweden)

    Cut Yulvizar

    2014-06-01

    Full Text Available One of the alternatives to antimicrobials in disease control is probiotic bacteria as microbial control agents. This research was carried out to obtain indegenous isolates of probiotic bacteria from digestive tract Cyprinus carpio. Selection criteria were appointed based on the capacity to produce the antibacterial compound against the pathogen and grow at pH 2. The research was conducted from May to July 2014 at Microbiology Laboratory, Biology Department, UNSYIAH. The research was carried out by experiment laboratories. The planting of the bacteria was carried out with the pour-plate method in nutrient agar medium. The result show that there are six bacterial isolates varied morphological colony and cell and able to produce antibacterial compounds for active against A.hydrophila and E. tarda.

  13. Minority Shareholders' Wealth Effects and Stock Market Development: Evidence from Increase-in-Ownership M&As

    OpenAIRE

    Petmezas, D

    2010-01-01

    This paper examines, using a global M&A data set, the relationship between the target firm’s minority shareholders’ returns and a country’s stock market development in deals in which large shareholders increase their ownership stakes. For the purpose of this study, we use two measures of stock market development: (1) turnover over GDP, and (2) turnover over market capitalization. We provide evidence supporting the view that minority shareholders in target firms gain significantly more in coun...

  14. GOL CONTRA! MAS... CONTRA QUEM? A LINGÜÍSTICA DE CORPUS E OS EQUIVALENTES DE TRADUÇÃO

    Directory of Open Access Journals (Sweden)

    Paulo Augusto Almeida Seemann

    2011-02-01

    Full Text Available O propósito deste estudo é mostrar como a Lingüística de Corpus pode ajudar o tradutor na busca por equivalentes tradutórios entre dois idiomas através de corpora comparáveis. Para exemplificar, procuramos equivalentes em espanhol para o termo “gol contra”, usado no Brasil com o sentido de o gol que um jogador de futebol faz contra o próprio time. Os corpora compostos de textos publicados em jornais do Brasil, da Espanha e da Argentina forneceram exemplos reais de uso, extraídos com o auxílio de ferramentas eletrônicas, e revelaram as formas como espanhóis e argentinos se referem ao “gol contra”.

  15. A INCLUSÃO DE STANDARDS SOCIAIS NOS ACORDOS DA OMC: UM ANTIGO, MAS AINDA CONTEMPORÂNEO DEBATE

    Directory of Open Access Journals (Sweden)

    Ícaro Ivvin de Almeida Costa Lima

    2015-12-01

    Full Text Available O presente artigo realiza um estudo acerca da problemática da vinculação de Standards Sociais aos acordos de comércio multilateral da OMC. Analisar-se-á, para tal, o papel assumido pelo Comércio Internacional no contexto da globalização, a importância da Organização Mundial do Comércio neste cenário e a imbricada inter-relação mantida entre os padrões sociais e as relações travadas no âmbito do comércio internacional. Adentrar-se-á, então, na análise das principais problemáticas e controvérsias que permeiam a questão da inserção das Cláusulas Sociais no âmbito da OMC. Apreciando, ademais, quais Standards Sociais têm sido propostos e os meios de sua vinculação na OMC.

  16. States' Participation Guidelines for Alternate Assessments Based on Modified Academic Achievement Standards (AA-MAS) in 2010. Synthesis Report 82

    Science.gov (United States)

    Lazarus, Sheryl S.; Hodgson, Jennifer R.; Price, Lynn M.; Thurlow, Martha L.

    2011-01-01

    Federal legislation requires that all students participate in state accountability systems. Most students with disabilities participate in the regular assessment, with or without accommodations. Students with more significant cognitive disabilities participate in the Alternate Assessment based on Alternate Achievement Standards (AA-AAS). A few…

  17. HEASARC Astronomical Archive: GLIESE2MAS - Gliese Catalog Stars with Accurate Coordinates and 2MASS Cross-Identifications

    Data.gov (United States)

    National Aeronautics and Space Administration — This table contains precise epoch 2000 coordinates and cross-identifications to sources in the 2MASS Point Source Catalog for nearly all stars in the Gliese,...

  18. Alguns apontamentos sobre literacia no Alto Douro: um quadro deficitário mas em valorização

    OpenAIRE

    Pina, Helena

    2015-01-01

    Cenário privilegiado, a Região Demarcada do Douro (RDD) ostenta um quadro paisagístico soberbo, para além de um património excecional que justificou a sua classificação pela UNESCO como ¿Património da Humanidade¿. Não obstante, os obstáculos ao seu desenvolvimento acumulam-se, nomeadamente os de âmbito demográfico, quadro muito problemático. Neste contexto, é imperativo questionar sobre o perfil sócio-cultural dos seus residentes, particularmente do produtor agrícola, dada a sua ascendência n...

  19. Boreal Ecosystem-Atmosphere Study/FFC-Winter (BOREAS) Campaign MODIS Airborne Simulator (MAS) Level-1B Data Products

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Boreal Ecosystem-Atmosphere Study/FFC-Winter (BOREAS) campaign was to study Snow and Ice Detection over Glacier National Park in Montana and...

  20. El Material Suplementario En Los Diccionarios Bilingues Espanol-Ingles Mas Representativos De Los Siglos XX y XXI

    Science.gov (United States)

    Fischer Dorantes, Erica

    2010-01-01

    This work is one of the first attempts to make a detailed and comparative analysis of the supplementary material of several bilingual English-Spanish dictionaries from the 20th and 21st centuries. It examines the historical development of prefaces and appendices in the most representative bilingual English-Spanish dictionaries that have…