WorldWideScience

Sample records for mendelevium 250

  1. Symposium commemorating the 25th anniversary of the discovery of mendelevium

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, G.T. (ed.)

    1980-01-01

    The Symposium honoring the 25th Anniversary of the discovery of mendelevium was held at the Lawrence Berkeley Laboratory on March 28, 1980. The following three papers were presented: Chemical Properties of Mendelevium; Nuclear Properties of Mendelevium; and Radioactive Decay of Md Isotopes. Besides these papers there were introductory remarks, reminiscences, and concluding remarks.

  2. Studies on some physico-chemical properties of the monovalent mendelevium

    International Nuclear Information System (INIS)

    Kamenskaya, A.N.; Mikheev, N.B.; Novichenko, V.L.

    1979-01-01

    It was established that Md 3+ reduced by Yb 2+ or Eu 2+ co-crystallizes with NaCl in water-ethanol solutions. The co-crystallization coefficient is independent of the relative quantities of the solid and liquid phase, of the concentration of the reducing agent in the concentration range from 1 to 8 mg/ml, and of the concentration of the chloride ion in the solution. Basing on the knowledge of anomalous mixed crystals and on the thermodynamical analysis of the formation of truly isomorphical solid solutions and anomalous mixed crystals, it was shown that mendelevium co-crystallizing with NaCl is in its monovalent state. Besides, it was concluded that up to 1.5 M chloride concentration the monovalent mendelevium does not form stable chloride complexes in water-ethanol solutions. (author)

  3. Chemical properties of mendelevium

    Energy Technology Data Exchange (ETDEWEB)

    Hulet, E.K.

    1980-11-01

    Even with the most intense ion beams and the largest available quantities of target isotope, about 10/sup 6/ atoms at a time is all the Md that can be produced for chemical studies. This lack of sufficient sample size coupled with the very short lifetimes of the few atoms produced has severely restricted the gathering and the broadness of our knowledge concerning the properties of Md and the heavier elements. To illustrate, the literature contains a mere eleven references to the chemical studies of Md, and none of these deal with bulk properties associated with the element bound in solid phases. Some of these findings are: Md was found to be more volatile than other actinide metals which lead to the belief that it is divalent in the metallic state; separation of Md from the other actinides can be accomplished either by reduction of Md/sup 3 +/ to the divalent state or by chromatographic separations with Md remaining in the tripositive state; extraction of Md/sup 2 +/ with bis(2-ethylhexyl)phosphoric acid is much poorer than the extraction of the neighboring tripositive actinides; attempts to oxidize Md/sup 3 +/ with sodium bismuthate failed to show any evidence for Md/sup 4 +/; reduction potential of Md/sup 3 +/ was found to be close to -0.1 volt; Md/sup 3 +/ can be reduced to Md(Hg) by sodium amalgams and by electrolysis; the electrochemical behavior of Md is very similar to that of Fm and can be summarized in the equation, Md/sup 2 +/ + 2e/sup -/ = Md(Hg) and E/sup 0/ = -1.50 V.; and Md cannot be reduced to a monovalent ion with Sm/sup 2 +/.

  4. Chemical properties of mendelevium

    International Nuclear Information System (INIS)

    Hulet, E.K.

    1980-01-01

    The isotope 256 Md is nearly always employed for chemical studies of this element. This nuclide can be made by bombardment of fractions of a microgram of 254 Es with intense alpha-particle beams which will produce about 10 6 atoms of 256 Md with a half-life of 77 minutes. Even with the most intense ion beams and the largest available quantities of target isotope, about 10 6 atoms at a time is all the Md that can be produced for chemical studies. This lack of sufficient sample size coupled with the very short lifetimes of the few atoms produced has severly restricted the gathering and broadening of our knowledge concerning the properties of Md and the heavier elements. To illustrate, the literature contains a mere eleven references to the chemical studies of Md, and none of these deal with bulk properties associated with element found in solid phases. Some of these findings are: Md was found to be more volatile than other actinide metals which lead to the belief that it is divalent in the metallic state; separation of Md from the other actinides can be accomplished either by reduction of Md to the divalent state or by chromatographic separations with Md remaining in the tripositive state; extraction of Md with bis(2-ethylhexyl)phosphoric acid is much poorer than the extraction of the neighboring tripositive actinides; attempts to oxidize Md wih sodium bismuthate failed to show any evidence of Md 4+ ; standard reduction potential of Md 3+ was found to be close to -0.1 volt; Md 3+ can be reduced to Md(Hg) by sodium amalgams and by electrolysis; the electrochemical behavior of Md is very similar to that of Fm and can be summarized in the equation, Md 2+ + 2e - = Md(Hg), and E 0 = 1.5 V

  5. Chemical properties of mendelevium

    International Nuclear Information System (INIS)

    Hulet, E.K.

    1980-11-01

    Even with the most intense ion beams and the largest available quantities of target isotope, about 10 6 atoms at a time is all the Md that can be produced for chemical studies. This lack of sufficient sample size coupled with the very short lifetimes of the few atoms produced has severely restricted the gathering and the broadness of our knowledge concerning the properties of Md and the heavier elements. To illustrate, the literature contains a mere eleven references to the chemical studies of Md, and none of these deal with bulk properties associated with the element bound in solid phases. Some of these findings are: Md was found to be more volatile than other actinide metals which lead to the belief that it is divalent in the metallic state; separation of Md from the other actinides can be accomplished either by reduction of Md 3+ to the divalent state or by chromatographic separations with Md remaining in the tripositive state; extraction of Md 2+ with bis(2-ethylhexyl)phosphoric acid is much poorer than the extraction of the neighboring tripositive actinides; attempts to oxidize Md 3+ with sodium bismuthate failed to show any evidence for Md 4+ ; reduction potential of Md 3+ was found to be close to -0.1 volt; Md 3+ can be reduced to Md(Hg) by sodium amalgams and by electrolysis; the electrochemical behavior of Md is very similar to that of Fm and can be summarized in the equation, Md 2+ + 2e - = Md(Hg) and E 0 = -1.50 V.; and Md cannot be reduced to a monovalent ion with Sm 2+

  6. ACT250 Districts

    Data.gov (United States)

    Vermont Center for Geographic Information — The ACT 250 Districts layer is part of a larger dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes...

  7. 30 CFR 250.1614 - Mud program.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Mud program. 250.1614 Section 250.1614 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1614 Mud program. (a) The quantities...

  8. 21 CFR 820.250 - Statistical techniques.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Statistical techniques. 820.250 Section 820.250...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques. (a... statistical techniques required for establishing, controlling, and verifying the acceptability of process...

  9. 30 CFR 250.1201 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 250.1201 Section 250.1201 Mineral... Security § 250.1201 Definitions. Terms not defined in this section have the meanings given in the... hydrocarbons attributable to one or more platforms, leases, units, or wells, in relation to the total...

  10. 30 CFR 250.604 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.604 Section 250.604... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.604 Hydrogen sulfide. When a well-workover operation is conducted in zones known to contain hydrogen sulfide (H2S) or in...

  11. 30 CFR 250.808 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.808 Section 250.808... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Safety Systems § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in zones where the presence of H2S...

  12. 30 CFR 250.504 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.504 Section 250.504... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.504 Hydrogen sulfide. When a well-completion operation is conducted in zones known to contain hydrogen sulfide (H2S) or in...

  13. 5 CFR 250.102 - Delegated authorities.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM may delegate its authority, including authority...

  14. 5 CFR 250.301 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Employee Surveys § 250.301 Definitions. In this part— Agency means an executive agency as defined in 5 U.S.C. 105. Executives are members...

  15. 7 CFR 250.17 - Reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Reports. 250.17 Section 250.17 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.17 Reports. (a) Inventory reports and receipt of donated foods. Distributing agencies shall complete and submit to the FNSRO...

  16. 30 CFR 250.1008 - Reports.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Reports. 250.1008 Section 250.1008 Mineral... OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1008 Reports. (a) The... lessee or right-of-way holder shall submit a report to the Regional Supervisor within 90 days after...

  17. 7 CFR 250.57 - Commodity schools.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Commodity schools. 250.57 Section 250.57 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.57 Commodity schools. (a) Categorization of commodity schools. Commodity...

  18. 7 CFR 250.2 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 250.2 Section 250.2 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General § 250.2 Administration. (a) Delegation to FNS. Within the Department, FNS shall act on behalf of the Department in the administration of the...

  19. 14 CFR 250.2 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS OVERSALES § 250.2 Applicability. This part applies to every carrier, as defined in § 250.1, with... more passenger seats, operating in (1) interstate air transportation or (2) foreign air transportation...

  20. English 304 & Communications 250: Professional Rhetorics

    Science.gov (United States)

    Hodgson, Justin

    2009-01-01

    This article provides a course overview of English 304 & Communications 250: Professional Rhetorics. This course was a pilot project instituted at Clemson University in spring of 2008. The project integrally linked English 304 (Business Writing) and Communications 250 (Public Speaking), requiring the same students to be enrolled in both 3…

  1. 7 CFR 250.15 - Financial management.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management. 250.15 Section 250.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... Financial management. (a) Distribution charges. (1) Recipient agencies may be required to pay part or all of...

  2. 40 CFR 170.250 - Decontamination.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Decontamination. 170.250 Section 170... PROTECTION STANDARD Standard for Pesticide Handlers § 170.250 Decontamination. (a) Requirement. During any..., decontamination supplies for washing off pesticides and pesticide residues. (b) General conditions. (1) The...

  3. 7 CFR 250.21 - Civil rights.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... rights. Distributing agencies, subdistributing agencies and recipient agencies shall comply with the Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil rights...

  4. 30 CFR 250.200 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... part. Non-conventional production or completion technology includes, but is not limited to, floating... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 250.200 Section 250.200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR...

  5. 36 CFR 2.50 - Special events.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There...

  6. 7 CFR 250.53 - Contract provisions.

    Science.gov (United States)

    2010-01-01

    ... the recipient agency's meal service in the school year or fiscal year (including both entitlement and... accordance with the contingencies in § 250.51(a); (2) The method and frequency by which crediting will occur...

  7. A 250 Msps CAMAC data acquisitions system

    International Nuclear Information System (INIS)

    Palama', G.F.; Neve, A.C.

    1995-09-01

    A 250 Msps CAMAC-Compatible Data Acquisition System (DAS) is presented. The DAS represents a first approach to the measurement of the number of primary ionization acts for particle identification in gaseous detectors

  8. Dicty_cDB: SHB250 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SH (Link to library) SHB250 (Link to dictyBase) - - - Contig-U16330-1 SHB250P (Link to Original site) SHB...250F 652 SHB250Z 665 SHB250P 1297 - - Show SHB250 Library SH (Link to library) Clone ID SHB...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SH/SHB2-C/SHB250Q.Seq.d/ Representative seq. ID SHB...250P (Link to Original site) Representative DNA sequence >SHB250 (SHB250Q) /CSM/SH/SHB2-C/SHB...ucing significant alignments: (bits) Value SHB250 (SHB250Q) /CSM/SH/SHB2-C/SHB250Q.Seq.d/ 1287 0.0 CHE549 (C

  9. 250th anniversary of the Restaurants

    OpenAIRE

    Mac Con Iomaire, Máirtín

    2015-01-01

    This podcast discusses the 250th anniversary of the birth of the restaurant in Paris, France and the varying theories as to who was the first restaurateur. It goes on to discuss the spread of restaurants to other cities including London and Dublin and the factors that influenced this development.

  10. Johann Wilhelm Krause 250 / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2007-01-01

    Eesti klassitsistliku arhitektuuri suurkuju ning Tartu Ülikooli arhitekti Johann Wilhelm Krause 250. sünniaastapäeva tähistati näitustega Tallinnas ja Tartus. Tartu Ülikooli raamatukogu kunstikogusse kuulub ligi 700 J. W. Krause loodud joonistust

  11. 5 CFR 250.203 - Agency responsibilities.

    Science.gov (United States)

    2010-01-01

    ... management on its overall mission performance. (2) Human capital accountability system. This system provides... MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in... and initiatives as appropriate, consistent with agency strategic plans and annual performance goals...

  12. 30 CFR 250.800 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... API RP 2RD (incorporated by reference as specified in 30 CFR 250.198); (3) Design all stationkeeping... requirements. (a) Production safety equipment shall be designed, installed, used, maintained, and tested in a... platforms (TLPs); spars, etc.), you must do all of the following: (1) Comply with API RP 14J (incorporated...

  13. 30 CFR 250.302 - Definitions concerning air quality.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions concerning air quality. 250.302 Section 250.302 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND... Definitions concerning air quality. For purposes of §§ 250.303 and 250.304 of this part: Air pollutant means...

  14. IceMap250—Automatic 250 m Sea Ice Extent Mapping Using MODIS Data

    Directory of Open Access Journals (Sweden)

    Charles Gignac

    2017-01-01

    Full Text Available The sea ice cover in the North evolves at a rapid rate. To adequately monitor this evolution, tools with high temporal and spatial resolution are needed. This paper presents IceMap250, an automatic sea ice extent mapping algorithm using MODIS reflective/emissive bands. Hybrid cloud-masking using both the MOD35 mask and a visibility mask, combined with downscaling of Bands 3–7 to 250 m, are utilized to delineate sea ice extent using a decision tree approach. IceMap250 was tested on scenes from the freeze-up, stable cover, and melt seasons in the Hudson Bay complex, in Northeastern Canada. IceMap250 first product is a daily composite sea ice presence map at 250 m. Validation based on comparisons with photo-interpreted ground-truth show the ability of the algorithm to achieve high classification accuracy, with kappa values systematically over 90%. IceMap250 second product is a weekly clear sky map that provides a synthesis of 7 days of daily composite maps. This map, produced using a majority filter, makes the sea ice presence map even more accurate by filtering out the effects of isolated classification errors. The synthesis maps show spatial consistency through time when compared to passive microwave and national ice services maps.

  15. Levels of 250Cf populated in the decay of 250Bk

    International Nuclear Information System (INIS)

    Uecke, J.W.

    1975-06-01

    The nuclide 250 Bk undergoes β-decay with a half-life of 3.2 h to 13.1 y 250 Cf. A study is undertaken of the excited states in 250 Cf populated by 250 Bk decay which results from the α-decay of 276d 254 Es. The general features of published level schemes for these nuclei are consistent with predictions of the Nilsson and collective models; however, there remain many undiscovered transitions and ambiguous or uncertain level assignments. In an attempt to confirm predictions of current theoretical models which account for nuclear level assignments in this nucleus, these gamma transitions and their levels have been studied. Twenty-eight new γ-rays were determined. The decay of 250 Bk is investigated primarily by high resolution gamma-ray singles spectrometry and supported in part by two-parameter gamma-gamma coincidence spectrometry. The equipment, comprised of a Ge(HP) and a large volume Ge(Li) detector, a 4096-channel two-parameter analyzer, and a PDP-8/e computer system, permitted significant improvement in sensitivity and accuracy over previous investigations on this nucleus. (11 figures, 2 tables) (U.S.)

  16. 5 CFR 250.202 - Office of Personnel Management responsibilities.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Office of Personnel Management responsibilities. 250.202 Section 250.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.202 Office of Personnel...

  17. 5 CFR 250.201 - Coverage and purpose.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Coverage and purpose. 250.201 Section 250.201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.201 Coverage and purpose. The Chief Human...

  18. 46 CFR 28.250 - High water alarms.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false High water alarms. 28.250 Section 28.250 Shipping COAST... Individuals On Board, or for Fish Tender Vessels Engaged in the Aleutian Trade § 28.250 High water alarms. On... operating station to indicate high water level in each of the following normally unmanned spaces: (a) A...

  19. 40 CFR 725.250 - Procedural requirements for the TERA.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Procedural requirements for the TERA. 725.250 Section 725.250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC... and Development Activities § 725.250 Procedural requirements for the TERA. General requirements for...

  20. 7 CFR 58.250 - Dry whole milk.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Dry whole milk. 58.250 Section 58.250 Agriculture... Products Bearing Usda Official Identification § 58.250 Dry whole milk. Dry whole milk in commercial bulk... Grades of Dry Whole Milk. Quality requirements for dry whole milk in consumer packages shall be for U.S...

  1. 7 CFR 250.1 - General purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 250.1 Section 250.1... AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES, ITS TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General § 250.1 General purpose and...

  2. 5 CFR 250.103 - Consequences of improper agency actions.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Consequences of improper agency actions. 250.103 Section 250.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.103 Consequences of improper agency actions. If OPM finds...

  3. 5 CFR 250.303 - Availability of results.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Availability of results. 250.303 Section 250.303 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Employee Surveys § 250.303 Availability of results. (a) Each agency will make the results of its annual survey available to th...

  4. 14 CFR 250.3 - Boarding priority rules.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Boarding priority rules. 250.3 Section 250...) ECONOMIC REGULATIONS OVERSALES § 250.3 Boarding priority rules. (a) Every carrier shall establish priority... boarding on an oversold flight in the event that an insufficient number of volunteers come forward. Such...

  5. 48 CFR 250.102-1 - Delegation of authority.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Delegation of authority. 250.102-1 Section 250.102-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 250.102-1...

  6. 250 Years of the State Survey

    Directory of Open Access Journals (Sweden)

    Ivana Wechselberger

    2014-06-01

    Full Text Available The first topographic survey of the Habsburg Monarchy was decreed by Maria Theresa 250 years ago, on May 13, 1764. A conference was held on the occasion of the anniversary by the Austrian State Geodetic Administration (BEV – Bundesamt für Eich- und Vermessungswesen and the Institute for Military Geosciences (IMG – Institut für Militärisches Geowesen in Vienna on May 13 and 14, 2014. The conference was sort of a time travel through Austrian state surveys. Historical development and methods of the first three state surveys (18th and 19th century were presented on the first conference day. Lectures were held by representatives of Austrian scientific institutions and new countries of the Monarchy. The second conference day was dedicated to the 4th state survey (20th century and its impact on civilian and military application and economy.

  7. ESP system development for 250C applications

    Energy Technology Data Exchange (ETDEWEB)

    Wonitoy, Kelvin [Baker Hughes (Canada)

    2011-07-01

    Steam Assisted Gravity Drainage (SAGD) is an oil extraction process for the production of oil sands. It presents many advantages in that it has a smaller environmental footprint than other oil recovery technologies and that it increases the production of oil. Baker Hughes has been concentrating its efforts on creating electrical submersible pumping (ESP) motors operating at high temperatures to improve the oil recovery process and have recently discovered that ultra temp ESP motors can be used in the SAGD to increase further the production of oil. The ultra temp ESP motor can operate at temperatures as high as 250 degree Celsius. Increasing the temperature of the reservoir decreases the viscosity of the oil, thus increasing production and the return on investment.

  8. 21 CFR 137.250 - White corn meal.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false White corn meal. 137.250 Section 137.250 Food and... Related Products § 137.250 White corn meal. (a) White corn meal is the food prepared by so grinding cleaned white corn that when tested by the method prescribed in paragraph (b)(2) of this section not less...

  9. 21 CFR 173.250 - Methyl alcohol residues.

    Science.gov (United States)

    2010-04-01

    ... FOR HUMAN CONSUMPTION (CONTINUED) SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION Solvents, Lubricants, Release Agents and Related Substances § 173.250 Methyl alcohol residues...

  10. 30 CFR 250.292 - What must the DWOP contain?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must the DWOP contain? 250.292 Section 250.292 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND... schematics and Safety Analysis Function Evaluation (SAFE) charts (API RP 14C, subsection 4.3c, incorporated...

  11. 30 CFR 250.510 - Diesel engine air intakes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Diesel engine air intakes. 250.510 Section 250... engine air intakes. Diesel engine air intakes must be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines that are continuously attended must be equipped with...

  12. 30 CFR 250.610 - Diesel engine air intakes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Diesel engine air intakes. 250.610 Section 250... engine air intakes. No later than May 31, 1989, diesel engine air intakes shall be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines which are continuously...

  13. 30 CFR 250.1631 - Safety device training.

    Science.gov (United States)

    2010-07-01

    ... operations to be performed; possible hazards to be encountered; and general safety considerations to be taken... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Safety device training. 250.1631 Section 250.1631 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND...

  14. 14 CFR 250.8 - Denied boarding compensation.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Denied boarding compensation. 250.8 Section... PROCEEDINGS) ECONOMIC REGULATIONS OVERSALES § 250.8 Denied boarding compensation. (a) Every carrier shall tender to a passenger eligible for denied boarding compensation, on the day and place the denied boarding...

  15. 14 CFR 250.2a - Policy regarding denied boarding.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Policy regarding denied boarding. 250.2a... PROCEEDINGS) ECONOMIC REGULATIONS OVERSALES § 250.2a Policy regarding denied boarding. In the event of an... confirmed reserved space on that flight are denied boarding involuntarily. ...

  16. 31 CFR 250.4 - Payment on awards.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment on awards. 250.4 Section 250.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... relationship to the incompetent; (2) The name and address of the person having care and custody of the...

  17. 40 CFR 795.250 - Developmental neurotoxicity screen.

    Science.gov (United States)

    2010-07-01

    ....250 Section 795.250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC... of home cage or novel test cage, and environmental distractions. (D) Additional information on the... Physiology and Psychology. 55: 888-892. (1962). (3) Brush, F.R. “Retention of aversively motivated behavior...

  18. 47 CFR 90.250 - Meteor burst communications.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Meteor burst communications. 90.250 Section 90... PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.250 Meteor burst communications. Meteor burst communications may be authorized for the use of private radio stations subject to...

  19. 30 CFR 250.1616 - Supervision, surveillance, and training.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Supervision, surveillance, and training. 250.1616 Section 250.1616 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Supervision, surveillance, and training. (a) The lessee shall provide onsite supervision of drilling...

  20. 41 CFR 60-250.24 - Drugs and alcohol.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Drugs and alcohol. 60-250... VETERANS Discrimination Prohibited § 60-250.24 Drugs and alcohol. (a) Specific activities permitted. The contractor: (1) May prohibit the illegal use of drugs and the use of alcohol at the workplace by all...

  1. 30 CFR 250.242 - What information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... § 250.248; (g) Air emissions information required by § 250.249; (h) Oil and hazardous substance spills...? 250.242 Section 250.242 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR....258; (q) Sulphur operations information required by § 250.259; (r) Coastal zone management information...

  2. The Varian MAT-250 mass spectrometer. Steady isotopes laboratory

    International Nuclear Information System (INIS)

    Hernandez M, V.; Tavera D, M.L.

    1997-01-01

    This work treats over the performance and applications of the Varian Mat-250 mass spectrometer which is in the environmental isotope laboratory. It can be applied over topics such as: ions formation, acceleration and collimation, ions separation, ions detection, data transformation, sampling, δ notation. (Author)

  3. 30 CFR 250.198 - Documents incorporated by reference.

    Science.gov (United States)

    2010-07-01

    ... RP 2FPS, RP for Planning, Designing, and Constructing Floating Production Systems; First Edition..., Chapter 4—Proving Systems, Section 5—Master-Meter Provers, Second Edition, May 2000, reaffirmed: August...; incorporated by reference at § 250.1203(b)(4); (47) API RP 2A-WSD, Recommended Practice for Planning, Designing...

  4. 7 CFR 250.63 - Commodity Supplemental Food Program.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Commodity Supplemental Food Program. 250.63 Section....63 Commodity Supplemental Food Program. (a) Distribution. The distributing agency shall distribute donated foods to the State agency which is designated by the State to administer the Commodity...

  5. 38 CFR 21.250 - Overview of employment services.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31 Employment Services § 21.250 Overview of employment services. (a) General. Employment services... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Overview of employment...

  6. 7 CFR 250.16 - Maintenance of records.

    Science.gov (United States)

    2010-01-01

    ... processor, food service management company, warehouse, or other entity which contracts with a distributing... management company, warehouse or other entity to maintain records required by this Section shall be... offer-and-acceptance system in accordance with § 250.48(e), the distributing agency shall maintain...

  7. 40 CFR 1065.250 - Nondispersive infra-red analyzer.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Nondispersive infra-red analyzer. 1065... POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Co and Co2 Measurements § 1065.250 Nondispersive infra-red analyzer. (a) Application. Use a nondispersive infra-red (NDIR) analyzer to measure CO...

  8. 30 CFR 250.286 - What is a DWOP?

    Science.gov (United States)

    2010-07-01

    ... development project, and any other project that uses non-conventional production or completion technology... Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Deepwater Operations Plans (dwop) § 250.286...

  9. 17 CFR 250.63 - Approval of reorganization fees.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Approval of reorganization... Reorganizations § 250.63 Approval of reorganization fees. All fees, expenses and remuneration, whether interim or final, to whomsoever paid for services rendered or to be rendered in connection with any reorganization...

  10. 30 CFR 250.1002 - Design requirements for DOI pipelines.

    Science.gov (United States)

    2010-07-01

    ... constructed of unbonded flexible pipe, you must design them according to the standards and procedures of API... for tension leg platforms and other floating platforms according to the design standards of API RP 2RD... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Design requirements for DOI pipelines. 250.1002...

  11. The Varian MAT-250 mass spectrometer. Steady isotopes laboratory; Espectrometro de masas Varian MAT-250. Laboratorio de isotopos estables

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez M, V.; Tavera D, M.L. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1997-07-01

    This work treats over the performance and applications of the Varian Mat-250 mass spectrometer which is in the environmental isotope laboratory. It can be applied over topics such as: ions formation, acceleration and collimation, ions separation, ions detection, data transformation, sampling, {delta} notation. (Author)

  12. 30 CFR 250.212 - What information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... by § 250.218; (g) Oil and hazardous substance spills information required by § 250.219; (h) Alaska... Section 250.212 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND... support facilities information required by § 250.225; (n) Coastal zone management information required by...

  13. 250 GHz cold tests for the LLNL CARM experiment

    International Nuclear Information System (INIS)

    Kulke, B.; Caplan, M.; Stever, R.

    1991-01-01

    A cyclotron autoresonant maser (CARM) experiment has been designed and built for operation at 250 GHz, in conjunction with the LLNL ARC induction linac. Beam parameters are 2 MeV, 1 kA, 30 ns. The RF structures tested consist of 7 mm diam, 9-18 cm long Bragg sections. These sections are electroformed, with 50-90 μm deep, sinusoidal ripples spaced at half wavelength intervals. A shallow ripple depth is essential in separating the desired, TE 11 resonance from neighboring resonances that are excited by mode conversion. The authors present code results and validating cold test data that illustrate the sensitivity of mode separation to ripple depth. They also present design calculations and calibration data at 250 GHz for a 2 m long, microwave diffraction tank

  14. 250 GHz cold tests for the LLNL CARM experiment

    International Nuclear Information System (INIS)

    Kulke, B.; Caplan, M.; Stever, R.D.

    1991-05-01

    A cyclotron autoresonant maser (CARM) experiment has been designed and built for operation at 250 GHz, in conjunction with the LLNL ARC induction linac. Beam parameters are 2 MeV, 1 kA, 30 ns. The RF structures tested consist of 7 mm diam, 9--18 cm long Bragg sections. These sections are electroformed, with 50--90 μm deep, sinusoidal ripples spaced at half wavelength intervals. A shallow ripple depth is essential in separating the desired, TE 11 resonance from neighboring resonances that are excited by mode conversion. We present code results and validating cold test data that illustrate the sensitivity of mode separation to ripple depth. We also present design calculations and calibration data at 250 GHz for a 2 m long, microwave diffraction tank

  15. Photographs of Failure 250, the first C-pile rupture

    Energy Technology Data Exchange (ETDEWEB)

    Chockie, L.J.

    1953-03-12

    This memorandum discusses four photographs of Failure 250, from Tube No. 2179-C, which are presented to show the type of failure as viewed in the 111-B cave. The first three photographs are successive rotations of the slug, illustrating the split-out portion at the base end of the piece. The fourth photo was focused on the split to show the bulging of the slug and the width of the opening.

  16. Towards 250 m mapping of terrestrial primary productivity over Canada

    Science.gov (United States)

    Gonsamo, A.; Chen, J. M.

    2011-12-01

    Terrestrial ecosystems are an important part of the climate and global change systems. Their role in climate change and in the global carbon cycle is yet to be well understood. Dataset from satellite earth observation, coupled with numerical models provide the unique tools for monitoring the spatial and temporal dynamics of territorial carbon cycle. The Boreal Ecosystems Productivity Simulator (BEPS) is a remote sensing based approach to quantifying the terrestrial carbon cycle by that gross and net primary productivity (GPP and NPP) and terrestrial carbon sinks and sources expressed as net ecosystem productivity (NEP). We have currently implemented a scheme to map the GPP, NPP and NEP at 250 m for first time over Canada using BEPS model. This is supplemented by improved mapping of land cover and leaf area index (LAI) at 250 m over Canada from MODIS satellite dataset. The results from BEPS are compared with MODIS GPP product and further evaluated with estimated LAI from various sources to evaluate if the results capture the trend in amount of photosynthetic biomass distributions. Final evaluation will be to validate both BEPS and MODIS primary productivity estimates over the Fluxnet sites over Canada. The primary evaluation indicate that BEPS GPP estimates capture the over storey LAI variations over Canada very well compared to MODIS GPP estimates. There is a large offset of MODIS GPP, over-estimating the lower GPP value compared to BEPS GPP estimates. These variations will further be validated based on the measured values from the Fluxnet tower measurements over Canadian. The high resolution GPP (NPP) products at 250 m will further be used to scale the outputs between different ecosystem productivity models, in our case the Canadian carbon budget model of Canadian forest sector CBM-CFS) and the Integrated Terrestrial Ecosystem Carbon model (InTEC).

  17. PENGARUH KELOMPOK REFERENSI TERHADAP KEPUTUSAN PEMBELIAN KAWASAKI NINJA 250 CC

    OpenAIRE

    Kartika WB, Sylvia; Sidig, Rosyid

    2018-01-01

    The purpose of this study is to examine the affect of reference groups  on purchasing decision of  Kawasaki Ninja 250 cc in the city of Jambi. Size of sample consist of 100 unit that chousen randomly. While data analysis used  multiple regression analysis. The results showed that simultaneouly   normative, value expression, and  informative have significant role. But, based on partiall test  normative has no significant affect. Hence,  reference group h...

  18. 77 FR 25720 - Determination That GRIFULVIN V (Griseofulvin Microcrystalline) Tablets, 250 Milligrams, Was Not...

    Science.gov (United States)

    2012-05-01

    ... HUMAN SERVICES Food and Drug Administration Determination That GRIFULVIN V (Griseofulvin...) has determined that GRIFULVIN V (griseofulvin microcrystalline) tablets, 250 milligrams (mg), was not... abbreviated new drug applications (ANDAs) for griseofulvin microcrystalline tablets, 250 mg, if all other...

  19. 30 CFR 250.457 - What equipment is required to monitor drilling fluids?

    Science.gov (United States)

    2010-07-01

    ... fluids? 250.457 Section 250.457 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Drilling Fluid Requirements § 250.457 What equipment is required to monitor drilling fluids? Once you establish drilling fluid returns, you must install and maintain the following drilling fluid-system...

  20. 21 CFR 250.100 - Amyl nitrite inhalant as a prescription drug for human use.

    Science.gov (United States)

    2010-04-01

    ... human use. 250.100 Section 250.100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL SPECIAL REQUIREMENTS FOR SPECIFIC HUMAN DRUGS New Drug or Prescription Status of Specific Drugs § 250.100 Amyl nitrite inhalant as a prescription drug for human use. (a...

  1. 30 CFR 250.109 - What documents must I prepare and maintain related to welding?

    Science.gov (United States)

    2010-07-01

    ... related to welding? 250.109 Section 250.109 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF... Performance Standards § 250.109 What documents must I prepare and maintain related to welding? (a) You must submit a Welding Plan to the District Manager before you begin drilling or production activities on a...

  2. 30 CFR 250.527 - What must I include in my casing pressure request?

    Science.gov (United States)

    2010-07-01

    ... request? 250.527 Section 250.527 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Operations Casing Pressure Management § 250.527 What must I include in my casing pressure request? The following information must be included in the casing pressure request: (a) API number; (b) Lease number; (c...

  3. 30 CFR 250.518 - What are the requirements for casing pressure management?

    Science.gov (United States)

    2010-07-01

    ... Operations Casing Pressure Management § 250.518 What are the requirements for casing pressure management? Once you install your wellhead, you must meet the casing pressure management requirements of API RP 90... management? 250.518 Section 250.518 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  4. 30 CFR 250.526 - What must I include in my notification of corrective action?

    Science.gov (United States)

    2010-07-01

    ... corrective action? 250.526 Section 250.526 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE...-Completion Operations Casing Pressure Management § 250.526 What must I include in my notification of... Operator name; (b) Area name and OCS block number; (c) Well name and API number; and (d) Casing diagnostic...

  5. 30 CFR 250.455 - What are the general requirements for a drilling fluid program?

    Science.gov (United States)

    2010-07-01

    ... drilling fluid program? 250.455 Section 250.455 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Gas Drilling Operations Drilling Fluid Requirements § 250.455 What are the general requirements for a drilling fluid program? You must design and implement your drilling fluid program to prevent the loss of...

  6. 30 CFR 250.184 - What is the amount of compensation for lease cancellation?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What is the amount of compensation for lease cancellation? 250.184 Section 250.184 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Requirements, Lease Term Extensions, and Lease Cancellations § 250.184 What is the amount of compensation for...

  7. 17 CFR 250.65 - Expenditures in connection with solicitation of proxies.

    Science.gov (United States)

    2010-04-01

    ... with solicitation of proxies. 250.65 Section 250.65 Commodity and Securities Exchanges SECURITIES AND... Solicitations and Reorganizations § 250.65 Expenditures in connection with solicitation of proxies. (a) General... solicitation of any proxy, consent, or authorization regarding any security of such company. (b) Exceptions...

  8. 30 CFR 250.915 - What are the CVA's primary responsibilities?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the CVA's primary responsibilities? 250.915 Section 250.915 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Platform Verification Program § 250.915 What are the CVA's primary responsibilities? (a) The CVA must...

  9. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Storage and inventory management of donated foods. 250... Donated Foods in Contracts With Food Service Management Companies § 250.52 Storage and inventory... general requirements in § 250.14(b) for the storage and inventory management of donated foods. (b) Storage...

  10. 30 CFR 250.231 - After receiving the EP, what will MMS do?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After receiving the EP, what will MMS do? 250.231 Section 250.231 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE... Decision Process for the Ep § 250.231 After receiving the EP, what will MMS do? (a) Determine whether...

  11. 30 CFR 250.266 - After receiving the DPP or DOCD, what will MMS do?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After receiving the DPP or DOCD, what will MMS do? 250.266 Section 250.266 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Decision Process for the Dpp Or Docd § 250.266 After receiving the DPP or DOCD, what will MMS do? (a...

  12. 30 CFR 250.1711 - When will MMS order me to permanently plug a well?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When will MMS order me to permanently plug a well? 250.1711 Section 250.1711 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Activities Permanently Plugging Wells § 250.1711 When will MMS order me to permanently plug a well? MMS will...

  13. 30 CFR 250.1406 - When will MMS notify me and provide penalty information?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When will MMS notify me and provide penalty information? 250.1406 Section 250.1406 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... (OCS) Civil Penalties § 250.1406 When will MMS notify me and provide penalty information? If the...

  14. 30 CFR 250.131 - Will MMS notify me before conducting an inspection?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS notify me before conducting an inspection? 250.131 Section 250.131 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... § 250.131 Will MMS notify me before conducting an inspection? MMS conducts both scheduled and...

  15. 30 CFR 250.123 - Will MMS allow gas storage on unleased lands?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS allow gas storage on unleased lands? 250.123 Section 250.123 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... § 250.123 Will MMS allow gas storage on unleased lands? You may not store gas on unleased lands unless...

  16. 40 CFR 421.250 - Applicability: Description of the primary precious metals and mercury subcategory.

    Science.gov (United States)

    2010-07-01

    ... primary precious metals and mercury subcategory. 421.250 Section 421.250 Protection of Environment... POINT SOURCE CATEGORY Primary Precious Metals and Mercury Subcategory § 421.250 Applicability: Description of the primary precious metals and mercury subcategory. The provisions of this subpart are...

  17. 17 CFR 250.64 - Scope of applications for approval of reorganization plans.

    Science.gov (United States)

    2010-04-01

    ... approval of reorganization plans. 250.64 Section 250.64 Commodity and Securities Exchanges SECURITIES AND... Solicitations and Reorganizations § 250.64 Scope of applications for approval of reorganization plans. Any application for approval of a plan of reorganization under section 11 (49 Stat. 820; 15 U.S.C. 79k), or...

  18. 30 CFR 250.1151 - How often must I conduct well production tests?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How often must I conduct well production tests? 250.1151 Section 250.1151 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Requirements Well Tests and Surveys § 250.1151 How...

  19. 30 CFR 250.460 - What are the requirements for conducting a well test?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the requirements for conducting a well test? 250.460 Section 250.460 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Other Drilling Requirements § 250.460...

  20. 33 CFR 96.250 - What documents and reports must a safety management system have?

    Science.gov (United States)

    2010-07-01

    ... safety management system have? 96.250 Section 96.250 Navigation and Navigable Waters COAST GUARD... SAFETY MANAGEMENT SYSTEMS Company and Vessel Safety Management Systems § 96.250 What documents and reports must a safety management system have? The documents and reports required for a safety management...

  1. 21 CFR 250.201 - Preparations for the treatment of pernicious anemia.

    Science.gov (United States)

    2010-04-01

    ... anemia. 250.201 Section 250.201 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... Drugs and Foods § 250.201 Preparations for the treatment of pernicious anemia. (a) The ninth announcement of the Anti-anemia Preparations Advisory Board of the United States Pharmacopeia is concerned with...

  2. Adjustable Shock Test Sled for Haversine Pulses at 250 fps

    Energy Technology Data Exchange (ETDEWEB)

    Hartwig, Troy [Honeywell Federal Manufacturing and Technologies, Kansas City, MO (United States); Hower, Brent [Honeywell Federal Manufacturing and Technologies, Kansas City, MO (United States); Seaholm, Aaron [Honeywell Federal Manufacturing and Technologies, Kansas City, MO (United States)

    2007-11-08

    New test requirements were developed by Sandia National Laboratory to simulate a regime of shock testing not previously performed at the Kansas City Plant operated by Honeywell Federal Manufacturing & Technologies. These environments were unique in that they involved amplitude of shock >1000g with relatively long pulse durations (greater 5 ms but less than 10 ms) and involved velocity changes up to 235 ft/sec. Ten months were available to develop, design, manufacture and prove-in this new capability. We designed a new shock sled to deliver this new family of shock environments in a laboratory test. The performance range of the new sled includes five specific shocks (1000 g – 8 ms, 1300 - 6 ms, 1500 g – 5.4 ms, 1950 g – 6 ms, 2250 g – 5.4 ms; all haversine shaped), and it also incorporates adjustability to accommodate new shocks within this range. These shock environments result in velocity changes ranging from 160 fps to 250 fps. The test sled accommodates test articles weighing up to 20 lbs and measuring up to 10” along any axis.

  3. Bionics by examples 250 scenarios from classical to modern times

    CERN Document Server

    Nachtigall, Werner

    2015-01-01

    Bionics means learning from the nature for the development of technology. The science of "bionics" itself is classified into several sections, from materials and structures over procedures and processes until evolution and optimization. Not all these areas, or only a few, are really known in the public and also in scientific literature. This includes the Lotus-effect, converted to the contamination-reduction of fassades and the shark-shed-effect, converted to the  resistance-reduction of airplanes. However, there are hundreds of highly interesting examples that contain the transformation of principles of the nature into technology. From the large number of these examples, 250 were selected for the present book according to "prehistory", "early-history", "classic" and "modern time". Most examples are new. Every example includes a printed page in a homogeneous arrangement. The examples from the field "modern time" are joint in blocks corresponding to the sub-disciplines of bionics.

  4. Test results from the LLNL 250 GHz CARM experiment

    International Nuclear Information System (INIS)

    Kulke, B.; Caplan, M.; Bubp, D.; Houck, T.; Rogers, D.; Trimble, D.; VanMaren, R.; Westenskow, G.; McDermott, D.B.; Luhmann, N.C. Jr.; Danly, B.

    1991-01-01

    The authors have completed the initial phase of a 250 GHz CARM experiment, driven by the 2 MeV, 1 kA, 30 ns induction linac at the LLNL ARC facility. A non-Brillouin, solid, electron beam is generated from a flux-threaded, thermionic cathode. As the beam traverses a 10 kG plateau produced by a superconducting magnet, ten percent of the beam energy is converted into rotational energy in a bifilar helix wiggler that produces a spiraling, 50 G, transverse magnetic field. The beam is then compressed to a 5 mm diameter as it drifts into a 30 kG plateau. For the present experiment, the CARM interaction region consisted of a single Bragg section resonator, followed by a smooth-bore amplifier section. Using high-pass filters, they have observed broadband output signals estimated to be at the several megawatt level in the range 140 to over 230 GHz. This is consistent with operation as a superradiant amplifier. Simultaneously, they also observed K a band power levels near 3 MW

  5. The Enduring Legacy of 250 Years of Pharmacology in Edinburgh.

    Science.gov (United States)

    Kelly, John S; Mackay, Angus V P

    2018-01-06

    In 1768, 250 years ago, the University of Edinburgh appointed Francis Home to the first chair of materia medica, the accumulated knowledge of materials used in healing. Francis Home and his colleagues were determined to improve the quality of medical training in Edinburgh by introducing a final examination and compiling a catalog of medicines validated by the Royal College of Physicians of Edinburgh. The catalog, known as the Edinburgh Pharmacopoeia, was a great success, partly due to the orderly nature of its contents, its routine editing to eliminate worthless entries, and the introduction of new treatments whose preparation was precisely documented. In a relatively short time, the worth of the Edinburgh Pharmacopoeia was recognized throughout Europe, America, and the British Empire. Today, the British and European Pharmacopoeias are catalogs of publicly available, legally enforceable standards for active pharmaceutical ingredients and finished dosage forms of pharmaceutical products and medical devices. Home and the many luminaries who succeeded him would surely take pleasure and pride in the fact that the mantra of today's medicines regulators worldwide is little different from that of these early visionaries: "To take better advantage of the best possible science in the service of the public health and our health-care systems" ( 1 , p. 492).

  6. Cinomose: achados epidemiológicos de 250 casos

    Directory of Open Access Journals (Sweden)

    Selwyn Arlington Headley

    2000-01-01

    Full Text Available Um levantamento nas necropsias de cães realizado de 1985-1997 no Departamento de Patologia Veterinária da Universidade Federal de Santa Maria (UFSM, RS, revelou que 11,7% (250/2136 dos caninos necropsiados apresentaram lesões histológicas e corpúsculos de inclusão consistentes com aqueles produzidos pelo vírus da cinomose. A maioria dos casos ocorreu durante os meses de inverno, em cães com menos de 1,5 ano de idade, provenientes da cidade de Santa Maria. A cinomose é considerada endêmica nessa cidade. Não houve diferença significativa na suscetibilidade entre machos e fêmeas infectados. Cães sem raça definida foram super-representados, mas as raças dolicocefálicas eram mais afetadas do que as braquicefálicas. Encefalopatia pelo vírus da cinomose com corpúsculos de inclusão característicos de cinomose, especialmente nos astrócitos, foi a lesão principal e ocorreu em 82% dos casos. Inclusões eosinofílicas características dessa enfermidade também foram encontradas nas células epiteliais da bexiga (15%, pulmão (6%, estômago (3%, rim (1% e tonsilas (0,5%.

  7. The Undergraduate ALFALFA Team: Outcomes for Over 250 Undergraduate Participants

    Science.gov (United States)

    Troischt, Parker; Koopmann, Rebecca A.; Haynes, Martha P.; ALFALFA Team

    2016-01-01

    The NSF-sponsored Undergraduate ALFALFA (Arecibo Legacy Fast ALFA) Team (UAT) is a consortium of 19 institutions founded to promote undergraduate research and faculty development within the extragalactic ALFALFA HI blind survey project and follow-up programs. In this talk we present outcomes for the more than 250 undergraduate students who have who have participated in the program during the 8 years of funding. 40% of these students have been women and members of underrepresented groups. To date 148 undergraduate students have attended annual workshops at Arecibo Observatory, interacting with faculty, graduate students, their peers, and Arecibo staff in lectures, group activities, tours, and observing runs. Team faculty have supervised 159 summer research projects and 120 academic year (e.g., senior thesis) projects. 68 students have traveled to Arecibo Observatory for observing runs and 55 have presented their results at national meetings such as the AAS. Through participation in the UAT, students are made aware of career paths they may not have previously considered. More than 90% of alumni are attending graduate school and/or pursuing a career in STEM. 42% of those pursuing graduate degrees in Physics or Astronomy are women. This work has been supported by NSF grants AST-0724918/0902211, AST-075267/0903394, AST-0725380, and AST-1211005

  8. Grammaire pour adolescents 250 exercices : niveau débutant

    CERN Document Server

    Bié, Nathalie

    2005-01-01

    Ce nouveau livre d'exercices de grammaire, de la collection Le Nouvel Entraînez-vous, s'adresse à un public d'adolescents débutants et faux débutants en français langue étrangère. L'ouvrage propose 250 exercices de compréhension et de mémorisation à travers des activités de déduction et de réemploi des notions grammaticales étudiées. Le contenu des exercices est organisé autour de contextes langagiers proches de la réalité des adolescents afin de placer la communication au cœur de l'apprentissage. L'introduction des contenus grammaticaux suit la même progression que les méthodes usuelles. Chaque chapitre débute par une séquence Rappel permettant à l'apprenant de revoir rapidement les règles grammaticales développées dans les exercices. Chaque exercice est introduit par une consigne brève et concise accompagnée d'un exemple. L'ouvrage a été conçu en tenant compte des centres d'intérêts des adolescents et propose de nombreuses illustrations intégrées aux exercices. A la fin d...

  9. 30 CFR 250.1152 - How do I conduct well tests?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I conduct well tests? 250.1152 Section 250.1152 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Requirements Well Tests and Surveys § 250.1152 How do I conduct well...

  10. Soil property maps of Africa at 250 m resolution

    Science.gov (United States)

    Kempen, Bas; Hengl, Tomislav; Heuvelink, Gerard B. M.; Leenaars, Johan G. B.; Walsh, Markus G.; MacMillan, Robert A.; Mendes de Jesus, Jorge S.; Shepherd, Keith; Sila, Andrew; Desta, Lulseged T.; Tondoh, Jérôme E.

    2015-04-01

    Vast areas of arable land in sub-Saharan Africa suffer from low soil fertility and physical soil constraints, and significant amounts of nutrients are lost yearly due to unsustainable soil management practices. At the same time it is expected that agriculture in Africa must intensify to meet the growing demand for food and fiber the next decades. Protection and sustainable management of Africa's soil resources is crucial to achieve this. In this context, comprehensive, accurate and up-to-date soil information is an essential input to any agricultural or environmental management or policy and decision-making model. In Africa, detailed soil information has been fragmented and limited to specific zones of interest for decades. To help bridge the soil information gap in Africa, the Africa Soil Information Service (AfSIS) project was established in 2008. AfSIS builds on recent advances in digital soil mapping, infrared spectroscopy, remote sensing, (geo)statistics, and integrated soil fertility management to improve the way soils are evaluated, mapped, and monitored. Over the period 2008-2014, the AfSIS project has compiled two soil profile data sets (about 28,000 unique locations): the Africa Soil Profiles (legacy) database and the AfSIS Sentinel Site (new soil samples) database -- the two data sets represent the most comprehensive soil sample database of the African continent to date. In addition a large set of high-resolution environmental data layers (covariates) was assembled. The point data were used in the AfSIS project to generate a set of maps of key soil properties for the African continent at 250 m spatial resolution: sand, silt and clay fractions, bulk density, organic carbon, total nitrogen, pH, cation-exchange capacity, exchangeable bases (Ca, K, Mg, Na), exchangeable acidity, and Al content. These properties were mapped for six depth intervals up to 2 m: 0-5 cm, 5-15 cm, 15-30 cm, 30-60 cm, 60-100 cm, and 100-200 cm. Random forests modelling was used to

  11. 41 CFR Appendix A to Part 61 - 250-Federal Contractor Veterans' Employment Report VETS-100

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 250-Federal Contractor Veterans' Employment Report VETS-100 A Appendix A to Part 61 Public Contracts and Property Management Other... Appendix A to Part 61-250—Federal Contractor Veterans' Employment Report VETS-100 ER05NO08.000 ER05NO08.001...

  12. 40 CFR 158.250 - Experimental use permit data requirements for human exposure.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Experimental use permit data requirements for human exposure. 158.250 Section 158.250 Protection of Environment ENVIRONMENTAL PROTECTION... Experimental use permit data requirements for human exposure. No data for applicator exposure and post...

  13. 30 CFR 250.806 - Safety and pollution prevention equipment quality assurance requirements.

    Science.gov (United States)

    2010-07-01

    ... quality assurance requirements. 250.806 Section 250.806 Mineral Resources MINERALS MANAGEMENT SERVICE... of Safety and Pollution Prevention Equipment Used in Offshore Oil and Gas Operations; and (ii) API... specifications of API Spec 6A and 6AV1. All SSSVs must meet the technical specifications of API Specification 14A...

  14. 30 CFR 250.1630 - Safety-system testing and records.

    Science.gov (United States)

    2010-07-01

    ... Section 250.1630 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL.... Testing must be in accordance with API RP 14C, Appendix D (incorporated by reference as specified in § 250.198). For safety system devices other than those listed in API RP 14C, Appendix D, you must utilize...

  15. 30 CFR 250.446 - What are the BOP maintenance and inspection requirements?

    Science.gov (United States)

    2010-07-01

    ....11, Maintenance; and Sections 17.12 and 18.12, Quality Management, described in API RP 53... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the BOP maintenance and inspection requirements? 250.446 Section 250.446 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  16. 30 CFR 250.459 - What are the safety requirements for drilling fluid-handling areas?

    Science.gov (United States)

    2010-07-01

    ... fluid-handling areas? 250.459 Section 250.459 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... drilling fluid-handling areas? You must classify drilling fluid-handling areas according to API RP 500... API RP 505, Recommended Practice for Classification of Locations for Electrical Installations at...

  17. 12 CFR 250.182 - Terms defining competitive effects of proposed mergers.

    Science.gov (United States)

    2010-01-01

    ... mergers. 250.182 Section 250.182 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS... competitive effects of proposed mergers. Under the Bank Merger Act (12 U.S.C. 1828(c)), a Federal Banking agency receiving a merger application must request the views of the other two banking agencies and the...

  18. 17 CFR 250.46 - Dividend declarations and payments on certain indebtedness.

    Science.gov (United States)

    2010-04-01

    ... payments on certain indebtedness. 250.46 Section 250.46 Commodity and Securities Exchanges SECURITIES AND... certain indebtedness. (a) Dividends. No registered holding company or subsidiary thereof shall declare or... to such declaration under the applicable provisions of the act. (b) Payments on certain indebtedness...

  19. 40 CFR 147.250 - State-administered program-Class II wells.

    Science.gov (United States)

    2010-07-01

    ... wells. 147.250 Section 147.250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS... Deputy Attorney General to the Administrator of EPA, “Re: Legal Authority of California Division of Oil...

  20. 17 CFR 250.8 - Exemption of subsidiaries subject to jurisdiction of Interstate Commerce Commission.

    Science.gov (United States)

    2010-04-01

    ... subject to jurisdiction of Interstate Commerce Commission. 250.8 Section 250.8 Commodity and Securities... to jurisdiction of Interstate Commerce Commission. Any subsidiary company of a registered holding company, which subsidiary is subject to the jurisdiction of the Interstate Commerce Commission but is not...

  1. 30 CFR 250.221 - What environmental monitoring information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What environmental monitoring information must accompany the EP? 250.221 Section 250.221 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... necessary under the MMPA. (c) Flower Garden Banks National Marine Sanctuary (FGBNMS). If you propose to...

  2. 30 CFR 250.252 - What environmental monitoring information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What environmental monitoring information must accompany the DPP or DOCD? 250.252 Section 250.252 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... incidental take of marine mammals as may be necessary under the MMPA. (c) Flower Garden Banks National Marine...

  3. Galvanic interactions of HE15 /MDN138 & HE15 /MDN250 alloys in natural seawater

    Science.gov (United States)

    Parthiban, G. T.; Subramanian, G.; Muthuraman, K.; Ramakrishna Rao, P.

    2017-06-01

    HE15 is a heat treatable high strength alloy with excellent machinability find wide applications in aerospace and defence industries. In view of their excellent mechanical properties, workability, machinability, heat treatment characteristics and good resistance to general and stress corrosion cracking, MDN138 & MDN250 have been widely used in petrochemical, nuclear and aerospace industries. The galvanic corrosion behaviour of the metal combinations HE15 /MDN138 and HE15 /MDN250, with 1:1 area ratio, has been studied in natural seawater using the open well facility of CECRI's Offshore Platform at Tuticorin for a year. The open circuit potentials of MDN138, MDN250 and HE15 of the individual metal, the galvanic potential and galvanic current of the couples HE15 /MDN138 and HE15 /MDN250 were periodically monitored throughout the study period. The calcareous deposits on MDN138 and MDN250 in galvanic contact with HE15 were analyzed using XRD. The electrochemical behaviors of MDN138, MDN250 and HE15 in seawater have been studied using an electrochemical work station. The surface characteristics of MDN138 and MDN250 in galvanic contact with HE15 have been examined with scanning electron microscope. The results of the study reveal that HE15 offered required amount of protection to MDN138 & MDN250.

  4. 17 CFR 250.103A - Liability for certain statements by issuers.

    Science.gov (United States)

    2010-04-01

    ... retained by the issuer shall be deemed not to be a fraudulent statement (as defined in paragraph (d) of... to: (1) A statement containing a projection of revenues, income (loss), earnings (loss) per share... statements by issuers. 250.103A Section 250.103A Commodity and Securities Exchanges SECURITIES AND EXCHANGE...

  5. 30 CFR 250.207 - What ancillary activities may I conduct?

    Science.gov (United States)

    2010-07-01

    ... surveys; or (c) Studies that model potential oil and hazardous substance spills, drilling muds and... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What ancillary activities may I conduct? 250.207 Section 250.207 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE...

  6. 17 CFR 250.93 - Accounts and records of mutual and subsidiary service companies.

    Science.gov (United States)

    2010-04-01

    ... and subsidiary service companies. 250.93 Section 250.93 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT... subsidiary service companies. Every mutual service company and every company whose organization and conduct...

  7. 17 CFR 250.94 - Annual reports by mutual and subsidiary service companies.

    Science.gov (United States)

    2010-04-01

    ... subsidiary service companies. 250.94 Section 250.94 Commodity and Securities Exchanges SECURITIES AND... companies. (a) On or before the first day of May in each calendar year, every mutual service company and every subsidiary service company whose organization and method of conducting business the Commission...

  8. 30 CFR 250.413 - What must my description of well drilling design criteria address?

    Science.gov (United States)

    2010-07-01

    ... drilling design criteria address? Your description of well drilling design criteria must address: (a) Pore... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must my description of well drilling design criteria address? 250.413 Section 250.413 Mineral Resources MINERALS MANAGEMENT SERVICE...

  9. 30 CFR 250.1504 - May I use alternative training methods?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I use alternative training methods? 250... Safety Training § 250.1504 May I use alternative training methods? You may use alternative training methods. These methods may include computer-based learning, films, or their equivalents. This training...

  10. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Storage and inventory management of donated foods. 250... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory management of donated foods. (a) General requirements. Distributing agencies, subdistributing agencies, and...

  11. 13 CFR 107.250 - Exclusion of stock options issued by Licensee from Management Expenses.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Exclusion of stock options issued by Licensee from Management Expenses. 107.250 Section 107.250 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Qualifying for an SBIC License Capitalizing An...

  12. 30 CFR 250.104 - How may I appeal a decision made under MMS regulations?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How may I appeal a decision made under MMS... of Terms § 250.104 How may I appeal a decision made under MMS regulations? To appeal orders or decisions issued under MMS regulations in 30 CFR parts 250 to 282, follow the procedures in 30 CFR part 290. ...

  13. 14 CFR 250.11 - Public disclosure of deliberate overbooking and boarding procedures.

    Science.gov (United States)

    2010-01-01

    ... and boarding procedures. 250.11 Section 250.11 Aeronautics and Space OFFICE OF THE SECRETARY... of deliberate overbooking and boarding procedures. (a) Every carrier shall cause to be displayed... airline will deny boarding to other persons in accordance with its particular boarding priority. With few...

  14. 14 CFR 250.6 - Exceptions to eligibility for denied boarding compensation.

    Science.gov (United States)

    2010-01-01

    ... boarding compensation. 250.6 Section 250.6 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... boarding compensation. A passenger denied boarding involuntarily from an oversold flight shall not be eligible for denied boarding compensation if: (a) The passenger does not comply fully with the carrier's...

  15. 14 CFR 250.9 - Written explanation of denied boarding compensation and boarding priorities.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Written explanation of denied boarding compensation and boarding priorities. 250.9 Section 250.9 Aeronautics and Space OFFICE OF THE SECRETARY... explanation of denied boarding compensation and boarding priorities. (a) Every carrier shall furnish...

  16. 14 CFR 250.2b - Carriers to request volunteers for denied boarding.

    Science.gov (United States)

    2010-01-01

    ... boarding. 250.2b Section 250.2b Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION... boarding. (a) In the event of an oversold flight, every carrier shall request volunteers for denied boarding before using any other boarding priority. A “volunteer” is a person who responds to the carrier's...

  17. 14 CFR 250.5 - Amount of denied boarding compensation for passengers denied boarding involuntarily.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Amount of denied boarding compensation for passengers denied boarding involuntarily. 250.5 Section 250.5 Aeronautics and Space OFFICE OF THE SECRETARY... boarding compensation for passengers denied boarding involuntarily. (a) Subject to the exceptions provided...

  18. 12 CFR 250.403 - Service of member bank and real estate investment company.

    Science.gov (United States)

    2010-01-01

    ... in the minds of the public with the bank that any financial reverses suffered by the company might... Board took the position that a closed-end investment company which was in process of organization and... investment company. 250.403 Section 250.403 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF...

  19. 30 CFR 250.294 - May I combine the Conceptual Plan and the DWOP?

    Science.gov (United States)

    2010-07-01

    ... (1,312 feet); and (b) The project is similar to projects involving non-conventional production or... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I combine the Conceptual Plan and the DWOP? 250.294 Section 250.294 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  20. 30 CFR 250.901 - What industry standards must your platform meet?

    Science.gov (United States)

    2010-07-01

    ...) American Petroleum Institute (API) Bulletin 2INT-DG, Interim Guidance for Design of Offshore Structures for... Design (incorporated by reference as specified in § 250.198); (8) API RP 2FPS, Recommended Practice for... (incorporated by reference as specified in § 250.198); (10) API RP 2RD, Design of Risers for Floating Production...

  1. 76 FR 14023 - Determination that ROCEPHIN (Ceftriaxone Sodium) Injection, 250 Milligrams, 500 Milligrams, 1...

    Science.gov (United States)

    2011-03-15

    ... HUMAN SERVICES Food and Drug Administration Determination that ROCEPHIN (Ceftriaxone Sodium) Injection... (ceftriaxone sodium) Injection, 250 milligrams (mg), 500mg, 1 gram (g), 2g, and 10g base/vial, approved under... refer to a listed drug. ROCEPHIN (ceftriaxone sodium) Injection, 250mg, 500mg, 1g, 2g, and 10g base/vial...

  2. 30 CFR 250.444 - What are the choke manifold requirements?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the choke manifold requirements? 250... Blowout Preventer (bop) System Requirements § 250.444 What are the choke manifold requirements? (a) Your BOP system must include a choke manifold that is suitable for the anticipated surface pressures...

  3. MODIS/Terra Surface Reflectance Daily L2G Global 250m SIN Grid V006

    Data.gov (United States)

    National Aeronautics and Space Administration — The MOD09GQ Version 6 product provides an estimate of the surface spectral reflectance of Terra MODIS 250 m bands 1-2 corrected for atmospheric conditions such as...

  4. 30 CFR 250.213 - What general information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... description and discussion of any new or unusual technology (see definition under § 250.200) you will use to... hydrocarbons. Include the estimated flow rate, total volume, and maximum duration of the potential blowout...

  5. MODIS/Aqua Calibrated Radiances 5-Min L1B Swath 250m V006

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS/Aqua Calibrated Radiances 5-Min L1B Swath 250m (MYD02QKM) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in...

  6. A multicenter randomized comparative investigation of ML Cu250, TCu-220C and Cu7 IUDs.

    Science.gov (United States)

    Goh, T H; Hutapea, H; Mccarthy, T; Sinnathuray, T A; Sivanesaratnam, V; Sen, D K; Nanafiah, M J; Simadjuntak, P; Lim, L S; Ratnam, S S

    1985-01-01

    The final analysis of 1725 interval insertions of the 3 IUDs is presented. The earlier observations were confirmed at: at 24 months, no significant differences were found between the TCu-220C and ML Cu250 IUDs though the TCu-220C had a lower gross pregnancy rate (2.0 versus 2.9) and the ML Cu250 had a lower expulsion rate (2.3 versus 4.1). Expulsions were more common with the Cu7 when compared to the ML Cu250 (p 0.001) and T-220C (p 0.01); pregnancy rates were also higher with p values of 0.05 and 0.01 respectively. Other use-related terminations were not significantly different among the 3 IUDs and continuation rates at 24 months were: Cu7, 69, TCu-220C, 73, and ML Cu250, 74.

  7. MODIS/Terra Calibrated Radiances 5-Min L1B Swath 250m V006

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS/Terra Calibrated Radiances 5-Min L1B Swath 250m (MOD02QKM) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located...

  8. Protein kinase A regulates AKAP250 (gravin) scaffold binding to the β2-adrenergic receptor

    OpenAIRE

    Tao, Jiangchuan; Wang, Hsien-yu; Malbon, Craig C.

    2003-01-01

    A-kinase-anchoring protein 250 (AKAP250; gravin) acts as a scaffold that binds protein kinase A (PKA), protein kinase C and protein phosphatases, associating reversibly with the β2-adrenergic receptor. The receptor-binding domain of the scaffold and the regulation of the receptor–scaffold association was revealed through mutagenesis and biochemical analyses. The AKAP domain found in other members of this superfamily is essential for the scaffold–receptor interactions. Gravin constructs lackin...

  9. 75 FR 62919 - Notice of Final Federal Agency Actions on the Route 250 Bypass Interchange at McIntire Road...

    Science.gov (United States)

    2010-10-13

    ... on the Route 250 Bypass Interchange at McIntire Road Project in Virginia AGENCY: Federal Highway.... 139(l)(1). The actions relate to the Route 250 Bypass Interchange at McIntire Road project in the City... Virginia: Route 250 Bypass Interchange at McIntire Road. The project would involve construction of a grade...

  10. 7 CFR 929.250 - Marketable quantity and allotment percentage for the 2000-2001 crop year.

    Science.gov (United States)

    2010-01-01

    ... 2000-2001 crop year. 929.250 Section 929.250 Agriculture Regulations of the Department of Agriculture... § 929.250 Marketable quantity and allotment percentage for the 2000-2001 crop year. The marketable quantity for the 2000-2001 crop year is set at 5.468 million barrels and the allotment percentage is...

  11. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Science.gov (United States)

    2010-07-01

    ... other material-handling equipment? 250.108 Section 250.108 Mineral Resources MINERALS MANAGEMENT SERVICE... Performance Standards § 250.108 What requirements must I follow for cranes and other material-handling... platform. (f) You must operate and maintain all other material-handling equipment in a manner that ensures...

  12. Generation of chimeric bispecific G250/anti-CD3 monoclonal antibody, a tool to combat renal cell carcinoma

    NARCIS (Netherlands)

    Luiten, R. M.; Coney, L. R.; Fleuren, G. J.; Warnaar, S. O.; Litvinov, S. V.

    1996-01-01

    The monoclonal antibody (MAb) G250 binds to a tumour-associated antigen, expressed in renal cell carcinoma (RCC), which has been demonstrated to be a suitable target for antibody-mediated immunotherapy. A bispecific antibody having both G250 and anti-CD3 specificity can cross-link G250

  13. 17 CFR 250.47 - Exemption of public utility subsidiaries as to certain securities issued to the Rural...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of public utility subsidiaries as to certain securities issued to the Rural Electrification Administration. 250.47 Section 250.47... Transactions 2 § 250.47 Exemption of public utility subsidiaries as to certain securities issued to the Rural...

  14. 17 CFR 250.12 - Exemption of certain public utility companies from the definition of subsidiary companies of...

    Science.gov (United States)

    2010-04-01

    ... utility companies from the definition of subsidiary companies of holding companies. 250.12 Section 250.12... REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.12 Exemption of certain public utility companies from the definition of subsidiary companies of holding companies...

  15. 17 CFR 250.95 - Reports required from affiliate service companies and companies principally engaged in performing...

    Science.gov (United States)

    2010-04-01

    ... affiliate service companies and companies principally engaged in performing services. 250.95 Section 250.95... REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.95 Reports required from affiliate service companies and companies principally engaged in performing services...

  16. 30 CFR 250.107 - What must I do to protect health, safety, property, and the environment?

    Science.gov (United States)

    2010-07-01

    ..., property, and the environment? 250.107 Section 250.107 Mineral Resources MINERALS MANAGEMENT SERVICE... Performance Standards § 250.107 What must I do to protect health, safety, property, and the environment? (a) You must protect health, safety, property, and the environment by: (1) Performing all operations in a...

  17. Digitalna topografska karta 1:250 000 - prema NATO standardima / Digital 1:250 000 topographic map designed in accordance with NATO standards

    Directory of Open Access Journals (Sweden)

    Mirko Borisov

    2007-10-01

    Full Text Available U radu se iznose iskustva pri izradi i oblikovanju vojne topografske karte razmera 1: 250 000. Karta se izrađuje u Vojnogeografskom institutu, po NATO standardima i u digitalnom obliku. Iskustva drugih država u kreiranju vojnih topografsko-kartografskih sistema i karata mogu se uporediti sa našim. Postupci izrade i ažuriranja vojnih topografskih karata su informatički podržani uz veliki stepen automatizacije pojedinih faza njihove izrade i osavremenjavanja. / The paper presents the design of the 1:250 000 military topographic map in the Military Geographical Institute (MGI in accordance with NATO standards and in a digital form. Other states' experiences in designing military topographic and cartographic systems and maps can be compared with those of the MGI's. The procedures of producing and updating military topographic maps are computer aided while particular phases are automated to a great extent.

  18. The system water-sodium oxide-silicon dioxide at 200, 250, and 300°

    Science.gov (United States)

    Rowe, Jack J.; Fournier, Robert O.; Morey, G.W.

    1967-01-01

    Studies were made of the H2O-Na2O-SiO2 system at its vapor pressure at 200, 250, and 300??. Three different sodium trisilicate hydrates were encountered in the investigation. At 300??, Na2Si3O7??5H2O is found: at 250??, Na2Si3O7??6H2O; and at 200??, Na2Si3O7??11H2O. The liquid immiscibility previously reported to exist in the system was found to be a quenching phenomenon caused by the decomposition of the hydrates to unstable, supersaturated, viscous liquids. Under conditions where equilibrium is maintained, as temperature is lowered, the hydrates decompose to quartz, sodium disilicate, and liquid. The retrograde solubility of sodium disilicate and its tendency to form supersaturated solutions during heating from 25 to 250?? account for higher solubilities reported by others than were found in this study. The solubility of sodium disilicate in water is 26% at 200??, 9% at 250??, and 5% at 300??. Sodium metasilicate solubility is 38% at 200?? and 34% at 250??; this compound is incongruently soluble at 300??.

  19. The N250 brain potential to personally familiar and newly learned faces and objects

    Directory of Open Access Journals (Sweden)

    Lara Justine Pierce

    2011-10-01

    Full Text Available Studies employing event-related potentials (ERPs have shown that when participants are monitoring for a novel target face, the presentation of their own face elicits an enhanced negative brain potential in posterior channels approximately 250 ms after stimulus onset. Here, we investigate whether the own-face N250 effect generalizes to other highly familiar objects, specifically, images of the participant’s own dog and own car. In our experiments, participants were asked to monitor for a pre-experimentally unfamiliar target face (Joe, a target dog (Experiment 1: Joe’s Dog or a target car (Experiment 2: Joe’s Car. The target face and object stimuli were presented with non-target foils that included novel face and object stimuli, the participant’s own face, their own dog (Experiment 1 and their own car (Experiment 2. The consistent findings across the two experiments were the following: 1 the N250 potential differentiated the target faces and objects from the non-target face and object foils and 2 despite being non-targets, the own face and own objects produced an N250 response that was equal in magnitude to the target faces and objects by the end of the experiment. Thus, as indicated by its response to personally familiar and recently familiarized faces and objects, the N250 component is a sensitive index of individuated representations in visual memory.

  20. A randomized trial of three copper IUDs (MLCu250, MLCu375 and Nova-T).

    Science.gov (United States)

    Bratt, H; Skjeldestad, F E; Cullberg Valentin, K

    1988-01-01

    A randomized prospective trial of three copper IUDs, Nova-T, MLCu375 and MLCu250, including 200 of each, is presented. Insertion was done at the hospital outpatient clinic on normally menstruating women and on women in puerperio. Follow-up was scheduled after 12, 24 and 36 months. Pregnancy rates were low for all 3 models. Pearl indices after 3 years were 0.5, 0.9 and 0.8 for Nova-T, MLCu375 and MLCu250 respectively (NS). Abnormal bleeding and/or pain was the most frequent termination cause. Minor differences in the termination rates because of abnormal bleeding and/or pain were found and are discussed. The continuation rates based on all medically relevant IUD removals were 74%, 73% and 81% after 3 years for Nova-T, MLCu375 and MLCu250 respectively. No important difference in clinical performance between the three copper IUDs could be demonstrated.

  1. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution

    DEFF Research Database (Denmark)

    Samuelsen, Camilla O; Baraznenok, Vera; Khorosjutina, Olga

    2003-01-01

    for Srb8 and Srb9. Here, we identify a TRAP240/ARC250 homologue in Schizosaccharomyces pombe and demonstrate that this protein, spTrap240, is stably associated with a larger form of Mediator, which also contains conserved homologues of Srb8, Srb10, and Srb11. We find that spTrap240 and Sch. pombe Srb8 (sp...... with the polymerase. Our findings provide experimental evidence for recent suggestions that TRAP230/ARC240 and TRAP240/ARC250 may indeed be the Srb8 and Srb9 homologues of mammalian Mediator. Apparently Srb8/TRAP230/ARC240, Srb9/TRAP240/ARC250, Srb10, and Srb11 constitute a conserved Mediator submodule, which...

  2. Continuously Tunable 250 GHz Gyrotron with a Double Disk Window for DNP-NMR Spectroscopy.

    Science.gov (United States)

    Jawla, Sudheer; Ni, Qing Zhe; Barnes, Alexander; Guss, William; Daviso, Eugenio; Herzfeld, Judith; Griffin, Robert; Temkin, Richard

    2013-01-01

    In this paper, we describe the design and experimental results from the rebuild of a 250 GHz gyrotron used for Dynamic Nuclear Polarization enhanced Nuclear Magnetic Resonance spectroscopy on a 380 MHz spectrometer. Tuning bandwidth of approximately 2 GHz is easily achieved at a fixed magnetic field of 9.24 T and a beam current of 95 mA producing an average output power of >10 W over the entire tuning band. This tube incorporates a double disk output sapphire window in order to maximize the transmission at 250.58 GHz. DNP Signal enhancement of >125 is achieved on a 13 C-Urea sample using this gyrotron.

  3. Proton-proton elastic scattering from 30 to 250 GeV/c

    International Nuclear Information System (INIS)

    Rusack, R.; Garbutt, D.; Siotis, I.; Gross, D.; Nitz, D.; Olsen, S.L.; Warren, G.; Abe, K.; Bomberowitz, R.; Goldhagen, P.; Sannes, F.; Tortora, J.

    1978-01-01

    We present measurements of the proton-proton elastic differential cross section for 1.0 2 and incident proton momenta between 30 and 250 GeV/c. The minimum in the cross section near t approx. = - 1.5 (GeV/c) 2 develops monotonically with increasing incident proton momentum and the cross section remains nonzero up to our highest incident momentum of 250 GeV/c. The cross section at the second maximum near t approx. = - 1.8 (GeV/c) 2 falls with increasing incident momentum up to 210 GeV/c after which it starts to rise

  4. 30 CFR 250.614 - Well-control fluids, equipment, and operations.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Well-control fluids, equipment, and operations... Operations § 250.614 Well-control fluids, equipment, and operations. The following requirements apply during all well-workover operations with the tree removed: (a) Well-control fluids, equipment, and operations...

  5. 30 CFR 250.514 - Well-control fluids, equipment, and operations.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Well-control fluids, equipment, and operations... Operations § 250.514 Well-control fluids, equipment, and operations. (a) Well-control fluids, equipment, and... shut in and secured. (b) The following well-control-fluid equipment shall be installed, maintained, and...

  6. 30 CFR 250.458 - What quantities of drilling fluids are required?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What quantities of drilling fluids are required... Drilling Fluid Requirements § 250.458 What quantities of drilling fluids are required? (a) You must use, maintain, and replenish quantities of drilling fluid and drilling fluid materials at the drill site as...

  7. 30 CFR 250.1507 - How will MMS measure training results?

    Science.gov (United States)

    2010-07-01

    ... program, using one or more of the methods in this section. (a) Training system audit. MMS or its... how effective the training was. (c) Employee or contract personnel testing. MMS or its authorized... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS measure training results? 250.1507...

  8. 12 CFR 563b.250 - Who must comply with these proxy solicitation provisions?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Who must comply with these proxy solicitation... TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Proxy Solicitation § 563b.250 Who must comply with these proxy solicitation provisions? (a) You must comply with these proxy solicitation...

  9. 30 CFR 250.113 - What procedures must I follow when welding?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What procedures must I follow when welding? 250....113 What procedures must I follow when welding? (a) Before you weld, you must move any equipment containing hydrocarbons or other flammable substances at least 35 feet horizontally from the welding area...

  10. 30 CFR 250.112 - What standards must my welding equipment meet?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What standards must my welding equipment meet... § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be equipped with spark arrestors and drip pans; (b...

  11. 30 CFR 250.111 - Who oversees operations under my welding plan?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who oversees operations under my welding plan... § 250.111 Who oversees operations under my welding plan? A welding supervisor or a designated person in charge must be thoroughly familiar with your welding plan. This person must ensure that each welder is...

  12. Study of solar features causing GMSs with 250γ H 400γ

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 61; Issue 1. Study of solar features causing GMSs with 250 < < ... Statistically, it is observed that maximum number of GMSs have occurred during the maximum solar activity years of 21st and 22nd solar cycles. A peculiar result has been observed during the years ...

  13. Production of $D^{\\pm}$ Mesons in $K^+$ Nucleon Collisions at 250 GeV

    Energy Technology Data Exchange (ETDEWEB)

    da Motta Filho, Helio [Rio de Janeiro, CBPF

    1993-11-01

    The $X_f$, $P^2_t$ and $p_t$ distribution of $D^{\\pm}$ mesons produced by 250 GeV $K^+$-nucleon interactions are measured through the decay channel $D^{\\pm} \\to K^{\\mp}\\pi^{\\pm} \\pi^{\\pm}$....

  14. 30 CFR 250.456 - What safe practices must the drilling fluid program follow?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What safe practices must the drilling fluid... Operations Drilling Fluid Requirements § 250.456 What safe practices must the drilling fluid program follow? Your drilling fluid program must include the following safe practices: (a) Before starting out of the...

  15. 30 CFR 250.1016 - Granting pipeline rights-of-way.

    Science.gov (United States)

    2010-07-01

    ... application and other required information are found to be in compliance with applicable laws and regulations... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1016 Granting pipeline rights-of-way. (a) In considering an application for a right-of-way, the...

  16. Alkaline electrolysis cell at high temperature and pressure of 250 °C and 42 bar

    DEFF Research Database (Denmark)

    Allebrod, Frank; Chatzichristodoulou, Christodoulos; Mogensen, Mogens Bjerg

    2013-01-01

    A new type of alkaline electrolysis cells with nickel foam based gas diffusion electrodes and KOH (aq) immobilized in mesoporous SrTiO3 has been developed and tested at temperatures and pressures up to 250 °C and 42 bar, respectively. Current densities of 1.0 A cm−2 have been measured at a cell...

  17. 30 CFR 250.1508 - What must I do when MMS administers written or oral tests?

    Science.gov (United States)

    2010-07-01

    ... Production Safety Training § 250.1508 What must I do when MMS administers written or oral tests? MMS or its... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I do when MMS administers written or... written or oral tests; and (b) Identify personnel by current position, years of experience in present...

  18. Silver City, NM AZ 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  19. LCD OF AIR INTAKE MANIFOLDS PHASE 2: FORD F250 AIR INTAKE MANIFOLD

    Science.gov (United States)

    The life cycle design methodology was applied to the design analysis of three alternatives for the lower plehum of the air intake manifold for us with a 5.4L F-250 truck engine: a sand cast aluminum, a lost core molded nylon composite, and a vibration welded nylon composite. The ...

  20. 30 CFR 250.169 - What effect does suspension have on my lease?

    Science.gov (United States)

    2010-07-01

    ... What effect does suspension have on my lease? (a) A suspension may extend the term of a lease (see § 250.180(b), (d), and (e)). The extension is equal to the length of time the suspension is in effect... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What effect does suspension have on my lease...

  1. 7 CFR 250.58 - Ordering donated foods and their provision to school food authorities.

    Science.gov (United States)

    2010-01-01

    ... ITS JURISDICTION National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.58... the Richard B. Russell National School Lunch Act (42 U.S.C. 1755(c)), the distributing agency must... multiplied by the number of reimbursable lunches served by the school food authority in the previous school...

  2. 7 CFR 250.61 - Child and Adult Care Food Program (CACFP).

    Science.gov (United States)

    2010-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.61 Child and Adult Care Food... of reimbursable lunches and suppers may be adjusted during, or at the end of the school year, in... donated foods. In accordance with the Richard B. Russell National School Lunch Act, and with 7 CFR part...

  3. 7 CFR 250.60 - Use of donated foods in the school food service.

    Science.gov (United States)

    2010-01-01

    ... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.60 Use of donated foods in the school food service. (a) Use of donated foods in school lunches and other meals or activities. The school food authority should use donated foods, as far as practical, in the lunches served to...

  4. 30 CFR 250.196 - Reimbursements for reproduction and processing costs.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Reimbursements for reproduction and processing... Reporting Requirements § 250.196 Reimbursements for reproduction and processing costs. (a) MMS will... retains the information. (c) When you request reimbursement, you must identify reproduction and processing...

  5. SoilGrids250m: Global gridded soil information based on machine learning

    NARCIS (Netherlands)

    Hengl, T.; Mendes de Jesus, J.S.; Heuvelink, G.B.M.; Ruiperez Gonzalez, M.; Kilibarda, Milan; Blagotic, Aleksandar; Wei, Shangguan; Wright, Marvin N.; Geng, Xiaoyuan; Bauer-Marschallinger, Bernhard; Guevara, Mario Antonio; Vargas, Rodrigo; MacMillan, Robert A.; Batjes, N.H.; Leenaars, J.G.B.; Carvalho Ribeiro, E.D.; Wheeler, Ichsani; Mantel, S.; Kempen, B.

    2017-01-01

    This paper describes the technical development and accuracy assessment of the most recent and improved version of the SoilGrids system at 250m resolution (June 2016 update). SoilGrids provides global predictions for standard numeric soil properties (organic carbon, bulk density, Cation Exchange

  6. 30 CFR 250.243 - What general information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... characteristics of the produced oil (see definition under 30 CFR 254.6) that you will handle or store at the... definition under § 250.200) you will use to carry out your proposed development and production activities. In... that you expect will have the highest volume of liquid hydrocarbons. Include the estimated flow rate...

  7. 21 CFR 250.101 - Amphetamine and methamphetamine inhalers regarded as prescription drugs.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Amphetamine and methamphetamine inhalers regarded... DRUGS New Drug or Prescription Status of Specific Drugs § 250.101 Amphetamine and methamphetamine inhalers regarded as prescription drugs. (a) Recurring reports of abuse and misuse of methamphetamine (also...

  8. Gallup, NM AZ 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  9. El Paso, TX NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  10. Tularosa, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  11. Las Cruces, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  12. Clovis, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  13. Muusikamaailm. Maailmaesiettekanne Krimmis. Herderi preemiad 2002. Opera Metz 250. Günter Wand 90 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2002-01-01

    Krimmis leiab aset Alemdar Karamanovi sümfoonia "Täideläinu" maailma esiettekanne. Johann Gottfried Herderi muusikapreemia sai nimekas rumeenia helilooja Aurel Stroe. Opera Metz Prantsusmaal tähistab oma 250ndat aastapäeva mitmete uuslavastustega. Dirigent Günter Wand tähistab 90ndat juubelit

  14. MODIS/Aqua Calibrated Radiances 5-Min L1B Swath 250m - NRT

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B Near Real Time (NRT) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88...

  15. 30 CFR 250.1162 - When may I burn produced liquid hydrocarbons?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may I burn produced liquid hydrocarbons... Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1162 When may I burn produced liquid hydrocarbons? (a) You must request and receive approval from the Regional Supervisor to burn any produced liquid...

  16. MODIS/Terra Calibrated Radiances 5-Min L1B Swath 250m V005

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88 micron region of the...

  17. Study of solar features causing GMSs with 250γ H 400γ

    Indian Academy of Sciences (India)

    PRAMANA c Indian Academy of Sciences. Vol. 61, No. 1. — journal of. July 2003 physics pp. 21–31. Study of solar features causing GMSs with. 250γ H 400γ. SANTOSH KUMAR1 ... Tilak P.G. College, Katni 483 501, India. £Email: s ... solar surface and are responsible for solar energetic particles (SEPs) events. Solar flares.

  18. 30 CFR 250.1003 - Installation, testing, and repair requirements for DOI pipelines.

    Science.gov (United States)

    2010-07-01

    ... and Pipeline Rights-of-Way § 250.1003 Installation, testing, and repair requirements for DOI pipelines... than 1 year. (2) Prior to returning a pipeline to service after a repair, the pipeline shall be... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Installation, testing, and repair requirements...

  19. Clifton, AZ NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  20. Aztec, NM CO 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  1. 30 CFR 250.136 - How will MMS determine if my operating performance is unacceptable?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS determine if my operating... Disqualification § 250.136 How will MMS determine if my operating performance is unacceptable? In determining if your operating performance is unacceptable, MMS will consider, individually or collectively: (a...

  2. 30 CFR 250.187 - What are MMS' incident reporting requirements?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are MMS' incident reporting requirements... Reporting Requirements § 250.187 What are MMS' incident reporting requirements? (a) You must report all... other permit issued by MMS, and that are related to operations resulting from the exercise of your...

  3. 30 CFR 250.1400 - How does MMS begin the civil penalty process?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How does MMS begin the civil penalty process...) Civil Penalties § 250.1400 How does MMS begin the civil penalty process? This subpart explains MMS's... other minerals operations in the OCS has a violation. Whenever MMS determines, on the basis of available...

  4. 30 CFR 250.119 - Will MMS approve subsurface gas storage?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS approve subsurface gas storage? 250....119 Will MMS approve subsurface gas storage? The Regional Supervisor may authorize subsurface storage of gas on the OCS, on and off-lease, for later commercial benefit. To receive MMS approval you must...

  5. 30 CFR 250.920 - What are the MMS requirements for assessment of fixed platforms?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the MMS requirements for assessment of... Structures Inspection, Maintenance, and Assessment of Platforms § 250.920 What are the MMS requirements for... in API RP 2A-WSD, Section 17.3. If MMS objects to the assessment category you used for your...

  6. 30 CFR 250.133 - Will MMS reimburse me for my expenses related to inspections?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS reimburse me for my expenses related... Inspection of Operations § 250.133 Will MMS reimburse me for my expenses related to inspections? Upon request, MMS will reimburse you for food, quarters, and transportation that you provide for MMS representatives...

  7. 30 CFR 250.191 - How does MMS conduct incident investigations?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How does MMS conduct incident investigations... Reporting Requirements § 250.191 How does MMS conduct incident investigations? Any investigation that MMS... meetings conducted by a chairperson appointed by MMS. The following requirements apply to any panel...

  8. Douglas, AZ NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  9. Brownfield, TX NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  10. Albuquerque, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  11. Tucumcari, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  12. Roswell, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  13. Socorro, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  14. Hobbs, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  15. Saint Johns, AZ NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  16. Parity violation in 232Th neutron resonances above 250 eV

    International Nuclear Information System (INIS)

    Sharapov, E. I.; Bowman, J. D.; Crawford, B. E.; Delheij, P. P. J.; Frankle, C. M.; Iinuma, M.; Knudson, J. N.; Lowie, L. Y.; Lynch, J. E.; Masaike, A.

    2000-01-01

    The analysis of parity nonconservation (PNC) measurements performed on 232 Th by the TRIPLE Collaboration has been extended to include the neutron energy range of 250 to 1900 eV. Below 250 eV all ten statistically significant parity violations have the same sign. However, at higher energies PNC effects of both signs were observed in the transmission of longitudinally polarized neutrons through a thick thorium target. Although the limited experimental energy resolution precluded analysis in terms of the longitudinal asymmetry, parity violations were observed and the cross section differences for positive and negative neutron helicities were obtained. For comparison, a similar analysis was performed on the data below 250 eV, for which longitudinal asymmetries were obtained previously. For energies below 250 eV, the p-wave neutron strength functions for the J=1/2 and J=3/2 states were extracted: S 1/2 1 =(1.68±0.61)x10 -4 and S 3/2 1 =(0.75±0.18)x10 -4 . The data provide constraints on the properties of local doorway states proposed to explain the PNC sign effect in thorium. (c) 2000 The American Physical Society

  17. MODIS/Terra Calibrated Radiances 5-Min L1B Swath 250m - NRT

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B Near Real Time (NRT) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88...

  18. MODIS/Terra Calibrated Radiances 5-Min L1B Swath 250m

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88 micron region of the...

  19. MODIS/Aqua Calibrated Radiances 5-Min L1B Swath 250m

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88 micron region of the...

  20. 33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Thomas Harbor, Charlotte... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.250 St. Thomas Harbor, Charlotte Amalie.... Thomas, V.I. of the United States and approaches thereto, including all waters under its jurisdiction, as...

  1. 30 CFR 250.110 - What must I include in my welding plan?

    Science.gov (United States)

    2010-07-01

    ... prevent spark-producing activities (i.e., grinding, abrasive blasting/cutting and arc-welding) in... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my welding plan? 250.110... must I include in my welding plan? You must include all of the following in the Welding Plan that you...

  2. 12 CFR 250.180 - Reports of changes in control of management.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Reports of changes in control of management... FEDERAL RESERVE SYSTEM MISCELLANEOUS INTERPRETATIONS Interpretations § 250.180 Reports of changes in control of management. (a) Under a statute enacted September 12, 1964 (Pub. L. 88-593; 78 Stat. 940) all...

  3. 7 CFR 250.13 - Distribution and control of donated foods.

    Science.gov (United States)

    2010-01-01

    .... (5) Commodity value. Distributing agencies shall establish a value for each commodity for school food... Department that donated food are unfit for human consumption at the time of delivery to the distributing... 7 Agriculture 4 2010-01-01 2010-01-01 false Distribution and control of donated foods. 250.13...

  4. 30 CFR 250.1629 - Additional production and fuel gas system requirements.

    Science.gov (United States)

    2010-07-01

    ... must be an approved type, designed and installed according to API RP 14C, API RP 14G, and either API RP... contained in § 250.1628 of this part). (b) Design, installation, and operation of additional production systems, including fuel gas handling safety systems. (1) Pressure and fired vessels must be designed...

  5. 30 CFR 250.908 - What are the minimum structural fatigue design requirements?

    Science.gov (United States)

    2010-07-01

    ... Platform Approval Program § 250.908 What are the minimum structural fatigue design requirements? (a) API RP 2A-WSD, Recommended Practice for Planning, Designing and Constructing Fixed Offshore Platforms... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the minimum structural fatigue design...

  6. 30 CFR 250.114 - How must I install and operate electrical equipment?

    Science.gov (United States)

    2010-07-01

    ... (incorporated by reference as specified in § 250.198), or API RP 14FZ, Recommended Practice for Design and.... (a) You must classify all areas according to API RP 500, Recommended Practice for Classification of... Division 2, or API RP 505, Recommended Practice for Classification of Locations for Electrical...

  7. Study of solar features causing GMSs with 250γ H 400γ

    Indian Academy of Sciences (India)

    The effect of solar features on geospheric conditions leading to geomagnetic storms (GMSs) with planetary index, p ≥ 20 and the range of horizontal component of the Earth's magnetic field such that 250 < < 400 has been investigated using interplanetary magnetic field (IMF), solar wind plasma (SWP) and solar ...

  8. On the economic dimensions of CSR: Exploring Fortune Global 250 reports

    NARCIS (Netherlands)

    Fortanier, F.N.; Kolk, A.

    2007-01-01

    The macro-level debate on the economic impact of multinational enterprises (MNEs) is still unsettled. This article explores micro-level evidence by examining what Fortune Global 250 firms themselves report about their economic impact. Such reporting embodies corporate attempts to account for their

  9. 30 CFR 250.116 - How do I determine producibility if my well is in the Gulf of Mexico?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I determine producibility if my well is in the Gulf of Mexico? 250.116 Section 250.116 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Performance Standards § 250.116 How do I...

  10. Experimental ethylene oxide neuropathy. Chronic exposure to 250 ppm in rats

    Energy Technology Data Exchange (ETDEWEB)

    Ohnishi, A.; Yamamoto, T.; Inoue, N.; Tanaka, I.; Koga, M.

    1985-12-01

    In Wistar rats subjected to a six-hour exposure to ethylene oxide (ETO) at the concentration of 250 parts per million once a day, five times a week for 9 months, histopathologic studies of myelinated fibers of the proximal sural, distal sural and peroneal nerves and of the fasciculus gracilis at the fifth thoracic and third cervical segments of the spinal cord were performed to reveal whether ETO of such concentration produces the degeneration of the primary sensory neuron. Throughout the study, no definite abnormality of the gait or posture was observed in both control and test rats. Qualitative histologic studies disclosed preferential distal axonal degeneration of myelinated fibers in both sural nerves and gracile fascicles in test rats, although the extent of the distribution and the severity of the degenerative findings were variable among test rats. Therefore, it was concluded that exposure to 250 ppm ethylene oxide produces central-peripheral distal axonal degeneration of the primary sensory neuron in rats.

  11. Radiation from a hot, thin plasma from 1 to 250 A

    International Nuclear Information System (INIS)

    Kato, T.

    1976-01-01

    A calculation of emission spectrum of a hot, low-density plasma in the region 1--250 A is presented. The mechanisms considered are electron collision-induced line emission, bremsstrahlung, and radiative recombination; and the temperature range studied is 10 5 --10 7 K. 795 lines are included. The elemental abundances of the ions of He, C, N, O, Ne, Mg, Si, S, Ca, Fe, and Ni were taken to be as in the solar corona. The line emission of Fe ions produces a maximum in the curve of an emission power between 1 and 250 A versus temperature around 10 6 K. The emission rate around 10 6 K is larger than the results calculated by Cox and Tucker and Tucker and Koren

  12. 12 CFR 250.400 - Service of open-end investment company.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Service of open-end investment company. 250.400....400 Service of open-end investment company. An open-end investment company is defined in section 5(a)(1) of the Investment Company Act of 1940 as a company “which is offering for sale or has outstanding...

  13. [A different approach to perceptive phenomena in 250 0-5-year old children].

    Science.gov (United States)

    Picasso, M T; Queirolo, F

    1991-05-01

    In this work there is a comparison between the different perceptions that a child can get from the dental instruments. The perception of dental instruments influences in a determinative way during dental attention. The sample consisted in the selection of 250 children whose ages ranges from 0 to 5 years. It was determined that age and experience influence in the perception of the objects as well as the different dental instruments used as variables.

  14. On the economic dimensions of CSR: Exploring Fortune Global 250 reports

    OpenAIRE

    Fortanier, F.N.; Kolk, A.

    2007-01-01

    The macro-level debate on the economic impact of multinational enterprises (MNEs) is still unsettled. This article explores micro-level evidence by examining what Fortune Global 250 firms themselves report about their economic impact. Such reporting embodies corporate attempts to account for their economic implications, in addition to the environmental and social aspects of their activities that have traditionally received more attention in the context of corporate responsibility. Firms' repo...

  15. Activity balance of a nuclear medicine therapy ward at a 250 MBQ limit of dismissal

    International Nuclear Information System (INIS)

    Haenscheid, H.; Lassmann, M.; Schlotter, H.; Reiners, C.

    1998-01-01

    A consistant utilisation of the raise of the limit of dismissal from 95 to 250 MBq 131 I increases the number of radioiodine therapies by a factor of 2.5. The fraction of the activity administered to patients that is excreted until dismissal averages to 72%, including 0.4% in the waste, 0.2% in contaminations of laundry and dishes, and [de

  16. Alveolar macrophage accumulation rates, for 28 nm and 250 nm PSL, are mediated by separate mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Moss, O R; Wong, V A, E-mail: moss@thehamner.or [Hamner Institutes for Health Sciences, Research Triangle Park, NC 27509-2137 (United States)

    2009-02-01

    When macrophages accumulate 28 nm and 250 nm diameter polystyrene latex (PSL) beads, the accumulation rates should reflect differences in molecular and cellular function. We used a confocal microscope to measure the accumulation rates of nanoparticles by F344-rat-alveolar macrophages (approx25,000 cells adhered to a 0.7 cm{sup 2} surface). Over the cells were layered 0.1 ml of media, and 0.1 ml of media-with-beads. Fresh cells were introduced for each exposure scenario. The maximum possible individual macrophage exposures were as follows: 8x10{sup 6}, 8x10{sup 5}, and 8x10{sup 4} 28 nm beads per macrophage; and 8x10{sup 4} and 1.12x10{sup 4} 250 nm beads per macrophage. Accumulation rates were estimated over 23 minutes. The increase in bead accumulation-rate matched changes in bead-availability: 7x increase for 250 nm beads; 100x increase for 28 nm beads; and 700x increase for all bead availabilities. The maximum sustained 28 nm bead accumulation rate was > 30,000 /min (for 5 min). Increases in bead accumulation could be explained by two mechanisms: bead-diffusion; and, for the macrophage, macropinocytosis. Also for the highest concentrations of 28 nm beads, we saw a colligative threshold - possibly due to beads masking the cell surface or obstructing cellular mechanisms.

  17. The case for a generic phytosanitary irradiation dose of 250 Gy for Lepidoptera eggs and larvae

    Science.gov (United States)

    Hallman, Guy J.; Arthur, Valter; Blackburn, Carl M.; Parker, Andrew G.

    2013-08-01

    The literature on ionizing irradiation of Lepidoptera is critically examined for a dose that could serve as a generic phytosanitary treatment for all eggs and larvae of that order, which contains many quarantine pests that inhibit trade in fresh agricultural commodities. The measure of efficacy used in deriving this dose is the prevention of emergence of normal-looking adults that are assumed not able to fly. A dose of 250 Gy is supported by many studies comprising 34 species in 11 lepidopteran families, including those of significant quarantine importance. Two studies with two different species found that doses >250 Gy were necessary, but both of these are contradicted by other studies showing that 10,000 individuals) testing for families other than Tortricidae (the most important quarantine family in the Lepidoptera). Because several large-scale studies have been done with tortricids a dose of 250 Gy could be justifiable for Tortricidae if it is not acceptable for the entire Lepidoptera at this time.

  18. Alveolar macrophage accumulation rates, for 28 nm and 250 nm PSL, are mediated by separate mechanisms

    Science.gov (United States)

    Moss, O. R.; Wong, V. A.

    2009-02-01

    When macrophages accumulate 28 nm and 250 nm diameter polystyrene latex (PSL) beads, the accumulation rates should reflect differences in molecular and cellular function. We used a confocal microscope to measure the accumulation rates of nanoparticles by F344-rat-alveolar macrophages (~25,000 cells adhered to a 0.7 cm2 surface). Over the cells were layered 0.1 ml of media, and 0.1 ml of media-with-beads. Fresh cells were introduced for each exposure scenario. The maximum possible individual macrophage exposures were as follows: 8x106, 8x105, and 8x104 28 nm beads per macrophage; and 8x104 and 1.12x104 250 nm beads per macrophage. Accumulation rates were estimated over 23 minutes. The increase in bead accumulation-rate matched changes in bead-availability: 7x increase for 250 nm beads; 100x increase for 28 nm beads; and 700x increase for all bead availabilities. The maximum sustained 28 nm bead accumulation rate was > 30,000 /min (for 5 min). Increases in bead accumulation could be explained by two mechanisms: bead-diffusion; and, for the macrophage, macropinocytosis. Also for the highest concentrations of 28 nm beads, we saw a colligative threshold -- possibly due to beads masking the cell surface or obstructing cellular mechanisms.

  19. Effect of 4 x 250 mg erythromycin on human gastrointestinal transit.

    Science.gov (United States)

    Ueberschaer, B; Ewe, K; Alles, U; Schmidtmann, I

    1995-07-01

    The motilin agonist erythromycin affects gastrointestinal motility. We studied its influence on gastric, intestinal, and colonic transit of indigestible solids. Ten healthy volunteers measured the gastrointestinal transit of a 6-8 mm metal sphere by metal detector with oral intake of 250 mg erythromycin q.i.d. or placebo in randomized order. Postprandial gastric emptying of the sphere after a standard meal was measured after a single i.v. dose of 250 mg erythromycin, subsequently followed by determination of small and large bowel transit. Motilin serum levels were measured for one hour. Gastric transit of the sphere was shortened from 243 +/- 34 to 72 +/- 46 min (mean +/- SD) (p = 0.002) and shifted from the interdigestive to the digestive phase. Small and large bowel transit were not influenced, and gastric transit times and motilin serum levels were not correlated. In conclusion, 250 mg erythromycin shortened postprandial gastric emptying of indigestible solids, most likely due to overcoming of pyloric sieving function by strong gastric antral contractions without effecting the transit through the lower part of the gastrointestinal tract.

  20. 30 CFR 250.150 - How do I name facilities and wells in the Gulf of Mexico Region?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I name facilities and wells in the Gulf of Mexico Region? 250.150 Section 250.150 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... and wells in the Gulf of Mexico Region? (a) Assign each facility a letter designation except for those...

  1. 30 CFR 250.421 - What are the casing and cementing requirements by type of casing string?

    Science.gov (United States)

    2010-07-01

    ... by type of casing string? 250.421 Section 250.421 Mineral Resources MINERALS MANAGEMENT SERVICE... requirements by type of casing string? The table in this section identifies specific design, setting, and cementing requirements for casing strings and liners. For the purposes of subpart D, the casing strings in...

  2. 30 CFR 250.445 - What are the requirements for kelly valves, inside BOPs, and drill-string safety valves?

    Science.gov (United States)

    2010-07-01

    ..., inside BOPs, and drill-string safety valves? 250.445 Section 250.445 Mineral Resources MINERALS... are the requirements for kelly valves, inside BOPs, and drill-string safety valves? You must use or... install an inside BOP for each size connection in the drill string; (f) A drill-string safety valve in the...

  3. Memory timeline: Brain ERP C250 (not P300) is an early biomarker of short-term storage.

    Science.gov (United States)

    Chapman, Robert M; Gardner, Margaret N; Mapstone, Mark; Dupree, Haley M; Antonsdottir, Inga M

    2015-04-16

    Brain event-related potentials (ERPs) offer a quantitative link between neurophysiological activity and cognitive performance. ERPs were measured while young adults performed a task that required storing a relevant stimulus in short-term memory. Using principal components analysis, ERP component C250 (maximum at 250 ms post-stimulus) was extracted from a set of ERPs that were separately averaged for various task conditions, including stimulus relevancy and stimulus sequence within a trial. C250 was more positive in response to task-specific stimuli that were successfully stored in short-term memory. This relationship between C250 and short-term memory storage of a stimulus was confirmed by a memory probe recall test where the behavioral recall of a stimulus was highly correlated with its C250 amplitude. ERP component P300 (and its subcomponents of P3a and P3b, which are commonly thought to represent memory operations) did not show a pattern of activation reflective of storing task-relevant stimuli. C250 precedes the P300, indicating that initial short-term memory storage may occur earlier than previously believed. Additionally, because C250 is so strongly predictive of a stimulus being stored in short-term memory, C250 may provide a strong index of early memory operations. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. 21 CFR 250.12 - Stramonium preparations labeled with directions for use in self-medication regarded as misbranded.

    Science.gov (United States)

    2010-04-01

    ... for use in self-medication regarded as misbranded. 250.12 Section 250.12 Food and Drugs FOOD AND DRUG... for use in self-medication regarded as misbranded. (a) Stramonium products for inhalation have been... ingredients, will be regarded as misbranded if they are labeled with directions for use in self-medication. (2...

  5. 20 CFR 410.250 - Effect of conviction of felonious and intentional homicide on entitlement to benefits.

    Science.gov (United States)

    2010-04-01

    ... intentional homicide on entitlement to benefits. 410.250 Section 410.250 Employees' Benefits SOCIAL SECURITY... conviction of felonious and intentional homicide on entitlement to benefits. An individual who has been finally convicted by a court of competent jurisdiction of the felonious and intentional homicide of a...

  6. 12 CFR 250.402 - Service as officer, director, or employee of licensee corporation under the Small Business...

    Science.gov (United States)

    2010-01-01

    ... licensee corporation under the Small Business Investment Act of 1958. 250.402 Section 250.402 Banks and... employee of licensee corporation under the Small Business Investment Act of 1958. (a) The Board of... corporation under the Small Business Investment Act of 1958 (15 U.S.C. 661 et seq.). It is understood that a...

  7. 30 CFR 250.192 - What reports and statistics must I submit relating to a hurricane, earthquake, or other natural...

    Science.gov (United States)

    2010-07-01

    ... relating to a hurricane, earthquake, or other natural occurrence? 250.192 Section 250.192 Mineral Resources... statistics must I submit relating to a hurricane, earthquake, or other natural occurrence? (a) You must submit evacuation statistics to the Regional Supervisor for a natural occurrence, such as a hurricane, a...

  8. Controlled GPR grave research: comparison of reflection profiles between 500 and 250 MHz antennae.

    Science.gov (United States)

    Schultz, John J; Martin, Michael M

    2011-06-15

    Since ground-penetrating radar (GPR) has become a popular search option for clandestine graves, controlled research is essential to determine the numerous variables that affect grave detection. The purpose of this study was to compare GPR reflection profiles of a controlled grave containing a large pig carcass and a blank control grave at 6 months interment in a Spodosol, which is a common soil type in Florida. Data collection was performed in perpendicular orientations over the graves using both 500 and 250 MHz antennae. Since reflection profiles are used to make initial in-field assessments during a forensic search, it is important for controlled research to evaluate this imagery option. Overall, it was possible to detect the grave containing a pig carcass at 6 months interment that was buried in a Spodosol using both the 500 and the 250 MHz antennae. While the 500 MHz antenna provided more detail within the grave containing a pig carcass, including detecting a soil disturbance and the pig carcass, the 250 MHz antenna also provided excellent imagery. Either antenna would provide optimal results for the type of soil that was sampled. Furthermore, it may be possible to locate actual forensic graves in this soil type when no response from the body is noted, as there may be a discernable response from the disturbed soil within the grave shaft and a noticeable disruption of the spodic horizon. Finally, survey orientation may also affect detection. Since data collection performed in two perpendicular directions detected the pig carcass and the grave floor of the control grave, data collection for an actual search involving a body interred for a long postmortem interval should be performed in both directions when time permits. Published by Elsevier Ireland Ltd.

  9. Dense grid of narrow bandpass filters for the JST/T250 telescope: summary of results

    Science.gov (United States)

    Brauneck, Ulf; Sprengard, Ruediger; Bourquin, Sebastien; Marín-Franch, Antonio

    2018-01-01

    On the Javalambre mountain in Spain, the Centro de Estudios de Fisica del Cosmos de Aragon has setup two telescopes, the JST/T250 and the JAST/T80. The JAST/T80 telescope integrates T80Cam, a large format, single CCD camera while the JST/T250 will mount the JPCam instrument, a 1.2Gpix camera equipped with a 14-CCD mosaic using the new large format e2v 9.2k×9.2k 10-μm pixel detectors. Both T80Cam and JPCam integrate a large number of filters in dimensions of 106.8×106.8 mm2 and 101.7×95.5 mm2, respectively. For this instrument, SCHOTT manufactured 56 specially designed steep edged bandpass interference filters, which were recently completed. The filter set consists of bandpass filters in the range between 348.5 and 910 nm and a longpass filter at 915 nm. Most of the filters have full-width at half-maximum (FWHM) of 14.5 nm and a blocking between 250 and 1050 nm with optical density of OD5. Absorptive color glass substrates in combination with interference filters were used to minimize residual reflection in order to avoid ghost images. In spite of containing absorptive elements, the filters show the maximum possible transmission. This was achieved by using magnetron sputtering for the filter coating process. The most important requirement for the continuous photometric survey is the tight tolerancing of the central wavelengths and FWHM of the filters. This insures each bandpass has a defined overlap with its neighbors. A high image quality required a low transmitted wavefront error (<λ/4 locally and <λ/2 on the whole aperture), which was achieved even by combining two or three substrates. We report on the spectral and interferometric results measured on the whole set of filters.

  10. Are we seeing accretion flows in a 250 kpc Lyα halo at z = 3?

    Science.gov (United States)

    Vernet, J.; Lehnert, M. D.; De Breuck, C.; Villar-Martín, M.; Wylezalek, D.; Falkendal, T.; Drouart, G.; Kolwa, S.; Humphrey, A.; Venemans, B. P.; Boulanger, F.

    2017-06-01

    Using MUSE on the ESO-VLT, we obtained a four-hour exposure of the z = 3.12 radio galaxy MRC 0316-257. We detect features down to 10-19 erg s-1 cm-2 arcsec-2, with the highest surface brightness regions reaching more than a factor of 100 higher. We find Lyα emission out to 250 kpc in projection from the active galactic nucleus (AGN). The emission shows arc-like morphologies arising at 150-250 kpc from the nucleus in projection, with the connected filamentary structures reaching down into the circumnuclear region. The most distant arc is offset by 700 km s-1 relative to circumnuclear HeIIλ1640 emission, which we assume to be at the systemic velocity. As we probe emission closer to the nucleus, the filamentary emission narrows in projection on the sky, the relative velocity decreases to 250 km s-1, and the line full-width at half maximum ranges from 300-700 km s-1. From UV line ratios, the emission on scales of 10s of kpc from the nucleus along a wide angle in the direction of the radio jets is clearly excited by the radio jets and ionizing radiation of the AGN. Assuming ionization equilibrium, the more extended emission outside of the axis of the jet direction would require 100% or more illumination to explain the observed surface brightness. High-speed (≳300 km s-1) shocks into rare gas would provide sufficiently high surface brightness. We discuss the possibility that the arcs of Lyα emission represent accretion shocks and the filamentary emission represents gas flows into the halo, and compare our results with gas accretion simulations. Based on observations made with ESO Telescopes at the La Silla Paranal Observatory under program ID 094.B-0699(A).

  11. Key components development progress updates of the 250W high power LPP-EUV light source

    Science.gov (United States)

    Yabu, Takayuki; Kawasuji, Yasufumi; Hori, Tsukasa; Okamoto, Takeshi; Tanaka, Hiroshi; Miyao, Kenichi; Ishii, Takuya; Watanabe, Yukio; Yanagida, Tatsuya; Shiraishi, Yutaka; Abe, Tamotsu; Kodama, Takeshi; Nakarai, Hiroaki; Yamazaki, Taku; Itou, Noritoshi; Saito, Takashi; Mizoguchi, Hakaru

    2017-10-01

    Gigaphoton Inc. is developing a CO2-Sn-LPP EUV light source based on unique and original technologies including a high power CO2laser with 15 nanosecond pulse duration, a solid-state pre-pulse laser with 10 picosecond pulse duration, a highly stabilized droplet generator, a precise laser-droplet shooting control system and a debris mitigation system using a magnetic field. In this paper, an update of the development progress of our 250W CO2-Sn-LPP EUV light source and of the key components is presented.

  12. Off-resonance transformer charging for 250-kV water Blumlein

    International Nuclear Information System (INIS)

    Cook, E.; Reginato, L.

    1978-01-01

    An off-resonance transformer for charging a 250-kV Blumlein system provides a viable alternative to other charging schemes by permitting the use of conventional thyratrons. Such a transformer must have reliability, a reasonable voltage step-up, and a non-reversing primary current. The analysis, design, and performance data for such a transformer are presented. The strong interrelationship between transformer design and Blumlein requirements necessitates that Blumlein description and design criterion be briefly presented prior to transformer design such that transformer load requirements be defined

  13. Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient

    Directory of Open Access Journals (Sweden)

    Jana Lass

    2017-01-01

    Full Text Available Limited available data for dosing in obesity of the medicines used in this case are discussed, with the emphasis on ertapenem. The case illustrates the difficulties in dosing medicines to morbidly overweight patients. The number of such patients is increasing but data on adequate doses of medicines are scarce. We demonstrate that ertapenem 1,5 g i.v. once daily provided adequate drug exposure for susceptible bacteria in a 250 kg patient with normal renal function. The case suggests the usefulness of therapeutic drug monitoring of antibiotics, especially in critically ill patients.

  14. Design of an induction linac driven CARM [Cyclotron Auto Resonance Maser] oscillator at 250 GHz

    International Nuclear Information System (INIS)

    Caplan, M.; Kulke, B.

    1990-01-01

    We present the design of a 250 GHz, 400 MW Cyclotron Auto Resonance Maser (CARM) oscillator driven by a 1 KA, 2 MeV electron beam produced by the induction linac at the ARC facility of LLNL. The oscillator circuit is designed as a feedback amplifier operating in the TE 11 mode at ten times cutoff terminated at each end with Bragg reflectors. Theory and cold test results are in good agreement for a manufactured Bragg reflector using 50 μm corrugations to ensure mode purity. The CARM is to be operational by February 1990. 3 figs., 2 tabs

  15. Pulse radiolysis studies of liquid heavy water at temperatures up to 250 degrees C

    International Nuclear Information System (INIS)

    Stuart, C.R.; Ouellette, D.C.; Elliot, A.J.

    2002-09-01

    This report documents the rate constants and associated activation energies for the reactions of the primary radical species, e aq - , ·OD and ·D, which are formed during the radiolysis of heavy water within the temperature range 20 to 250 o C. These heavy-water data have been compared with the corresponding information for light water. These kinetic data form part of the database that is required to model the aqueous radiation chemistry that occurs within the core of the heavy water cooled and moderated CANDU reactor. (author)

  16. Estabilidad acelerada de tabletas de levodopa-carbidopa (250-25 mg

    Directory of Open Access Journals (Sweden)

    Mirna Fernández Cervera

    2001-08-01

    Full Text Available Se realizó el estudio de estabilidad acelerada de tabletas de levodopa-carbidopa (250-25 mg con el empleo de un método de cromatografía líquida de alta resolución y se comprobó su especificidad para estos fines. Se analizó la influencia de medios degradantes artificiales sobre los productos activos, además del efecto de la humedad sobre la estabilidad del producto, colocándolo en hidrostatos con humedades controladas. Este medicamento, producción nacional, cumplió con las especificaciones de calidad descritas en la USP 23 y mostró una alta estabilidad térmica.An accelerated stability study of levodopa-carbidopa tablets (250-25 mg was made using high-performance liquid chromatography which specificity for these purposes was proved. The influence of the artificial degrading media on the active products was analyzed and also the effect of humidity on the product´s satbility was examined after placing the tablets into hydrostats under controlled humidity levels. This domestically-made drug met the quality standards described in USP 23 and showed high heat stability.

  17. Radiation damage studies on STAR250 CMOS sensor at 300 keV for electron microscopy

    International Nuclear Information System (INIS)

    Faruqi, A.R.; Henderson, R.; Holmes, J.

    2006-01-01

    There is a pressing need for better electronic detectors to replace film for recording high-resolution images using electron cryomicroscopy. Our previous work has shown that direct electron detection in CMOS sensors is promising in terms of resolution and efficiency at 120 keV [A.R. Faruqi, R. Henderson, M. Prydderch, R. Turchetta, P. Allport, A. Evans, Nucl. Instr. and Meth. 546 (2005) 170], but in addition, the detectors must not be damaged by the electron irradiation. We now present new measurements on the radiation tolerance of a 25 μm pitch CMOS active-pixel sensor, the STAR250, which was designed by FillFactory using radiation-hard technology for space applications. Our tests on the STAR250 aimed to establish the imaging performance at 300 keV following irradiation. The residual contrast, measured on shadow images of a 300 mesh grid, was >80% after corrections for increased dark current, following irradiation with up to 5x10 7 electrons/pixel (equivalent to 80,000 electron/μm 2 ). A CMOS sensor with this degree of radiation tolerance would survive a year of normal usage for low-dose electron cryomicroscopy, which is a very useful advance

  18. Shared technologies in the development of the Titan 250 gas turbine system

    Energy Technology Data Exchange (ETDEWEB)

    Knodle, M.S.; Novaresi, M.A. [Solar Turbines Inc., San Diego, CA (United States). Titan Gas Turbine Systems Division

    2009-07-01

    Development of the Titan 250 industrial gas turbine system began in 2005 in response to demands from the petroleum industry and electricity producers for higher performance industrial gas turbine products in the 15-30 MW (25,000-45,000 hp) power range. The Titan 250 is Solar Turbine's most powerful package and its evolutionary hybrid-type design approach was based on shared aerodynamic, thermal, mechanical, and combustion technologies borrowed from the Taurus 65TM, Titan 130TM, and Mercury 50TM gas turbine systems. It produces 50 per cent more power than the Titan 130, while providing 40 per cent shaft efficiency with significantly fewer emissions. Thorough combustion system testing, use of proven materials, and hot section cooling provided a solid design basis. The engine is a two-shaft design that includes a 16-stage axial-flow compressor, a dry low emissions combustor for low NOx and CO output, a two-stage gas producer turbine operating at a turbine rotor inlet temperature of 1204 degrees C, and a three-stage, all-shrouded blade power turbine for maximum efficiency. The design also minimizes maintenance intervals to increase equipment availability. The gas turbine and gas compressor have been tested in component, subsystem, and full-scale development, and will be starting field operation in late 2009 to verify performance and mechanical integrity under all operating conditions. 3 refs., 1 tab., 26 figs.

  19. Ternary Fission of {sup 249}Cf(n,f) and {sup 250}Cf(SF)

    Energy Technology Data Exchange (ETDEWEB)

    University of Gent, B-9000 Gent, Belgium; CEA Cadarache, F-13108 Saint-Paul-lez-Durance, France; Institute Laue-Langevin, F-38042 Grenoble, France; EC-JRC Institute for Reference Materials and Measurements, B-2440 Geel, Belgium; Wadsworth Center, New York State Department of Health, Albany NY 12201, USA; Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; Vermote, S.; Wagemans, C.; Serot, O.; Soldner, T.; Geltenbort, P.; Gils, J. Van; Almahamid, I.; Tian, G.; Rao, L.

    2011-09-01

    During the last years, several Cm and Cf isotopes have been studied by our research group in the frame of a systematic investigation of gas emission characteristics in ternary fission. Here we report on new results on the energy distribution and the emission probability of {sup 3}H, {sup 4}He and {sup 6}He particles emitted in the spontaneous ternary fission of {sup 250}Cf (E{sub exc} = 0 MeV) and in the neutron induced ternary fission of {sup 249}Cf (E{sub exc} = 6.625 MeV). Both measurements were performed using suited and well-calibrated ΔE-E telescope detectors, at the IRMM (Geel, Belgium) for the spontaneous fission and at the very intense neutron beam PF1b at the Institute Laue-Langevin (Grenoble, France) for the neutron induced fission measurement. In this way, the existing database can be enlarged with new results for Z=98 isotopes, which is important for the systematic investigation. Moreover, the investigation of the 'isotope couple' {sup 249}Cf(n,f) - {sup 250}Cf(SF), together with corresponding data for other isotopes, will yield valuable information on the influence of the excitation energy on the particle emission probabilities.

  20. Protein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptor.

    Science.gov (United States)

    Tao, Jiangchuan; Wang, Hsien-Yu; Malbon, Craig C

    2003-12-15

    A-kinase-anchoring protein 250 (AKAP250; gravin) acts as a scaffold that binds protein kinase A (PKA), protein kinase C and protein phosphatases, associating reversibly with the beta(2)-adrenergic receptor. The receptor-binding domain of the scaffold and the regulation of the receptor-scaffold association was revealed through mutagenesis and biochemical analyses. The AKAP domain found in other members of this superfamily is essential for the scaffold-receptor interactions. Gravin constructs lacking the AKAP domain displayed no binding to the receptor. Metabolic labeling studies in vivo demonstrate agonist-stimulated phosphorylation of gravin and enhanced gravin-receptor association. Analysis of the AKAP domain revealed two canonical PKA sites phosphorylated in response to elevated cAMP, blocked by PKA inhibitor, and essential for scaffold-receptor association and for resensitization of the receptor. The AKAP appears to provide the catalytic PKA activity responsible for phosphorylation of the scaffold in response to agonist activation of the receptor as well as for the association of the scaffold with the receptor, a step critical to receptor resensitization.

  1. Motor power calculation for driving conveyor chain in gamma irradiator BATAN 2x250 k curie

    International Nuclear Information System (INIS)

    Ari Satmoko; Syamsurrijal Ramdja; Sutomo Budihardjo

    2010-01-01

    Recently, an Irradiator BATAN 2X250 k Curie for agricultural product is under design. The installation is provided by the gamma source about 2x250 k Curie. Agricultural products are carried into carriers and these carriers are hanged on the conveyor chain. The chain moves into a radiation chamber following the trajectoire. The chain is drived by motor. For this reason, the calculation is performed to determine the motor power. After resolving the force equilibrium equation, the force and power of the motor needed to drive the chain are obtained. Numerical method by using V Basic language is used to resolve the equation. The calculation result shows the correlation between friction coefficient and motor power. From the evaluation, it is decided that the friction coefficient should be less than 0,015. By this friction, the motor power is about 3. 13 k Watt. From the evaluation, it is also obtained that the radius of the curve trajectory shall not be too small. Combination between high friction and small curve radius could lead to the locked condition in which high power motor are not be able to move the conveyor chain). (author)

  2. Optimized production and characterization of a detergent-stable protease from Lysinibacillus fusiformis C250R.

    Science.gov (United States)

    Mechri, Sondes; Kriaa, Mouna; Ben Elhoul Berrouina, Mouna; Omrane Benmrad, Maroua; Zaraî Jaouadi, Nadia; Rekik, Hatem; Bouacem, Khelifa; Bouanane-Darenfed, Amel; Chebbi, Alif; Sayadi, Sami; Chamkha, Mohamed; Bejar, Samir; Jaouadi, Bassem

    2017-08-01

    In this study, we aimed to optimize the cultural and nutritional conditions for protease production by Lysinibacillus fusiformis strain C250R in submerged fermentation process using statistical methodology. The most significant factors (gruel, wheat bran, yeast extract, and FeSO 4 ) were identified by Plackett-Burman design. Response surface methodology (RSM) was used to determine the optimum levels of the screened factors and their interaction. Under the optimized conditions, protease yield 3100U/mL was 4.5 folds higher than those obtained by the use of the initial conditions (680U/mL). Additionally, a new extracellular 51kDa-protease, designated SAPLF, was purified and biochemically characterized from strain C250R. It shows optimum activity at 70°C and pH 10. Its half-life times at 70 and 80°C were 10 and 6-h, respectively. Irreversible inhibition of enzyme activity of SAPLF with serine protease inhibitors demonstrated that it belongs to the serine protease family. Interestingly, its catalytic efficiency was higher than that of SPVP from Aeribacillus pallidus strain VP3 and Alcalase Ultra 2.5L from Bacillus licheniformis. This study demonstrated that SAPLF has a high detergent compatibility and an excellent stain removal compared to Alcalase Ultra 2.5L; which offers an interesting potential for its application in the laundry detergent industry. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. MODIS/Terra Near Real Time (NRT) Vegetation Indices Daily Rolling-8-Day L3 Global 250m SIN Grid

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS Near Real Time (NRT) level-3 Vegetation Indices Daily Rolling8Day data, MOD13Q4N, are provided everyday at 250-meter spatial resolution as a gridded leve-3...

  4. Patterns of copper loss--a comparison of the multiload Cu250, TCu-220C and Cu7 IUDs.

    Science.gov (United States)

    Goh, T H; Tong, S L

    1986-04-01

    The rate of copper loss from 329 IUDs (Multiload Cu250, TCu-220C and Cu7) which had been terminated for various reasons after 0.5-46 months in-utero were determined. All 3 IUDs showed a wide scatter of release rates with no significant differences between the ML Cu250 and the Cu7. The TCu-220C showed the highest rates and in contrast to the ML Cu250 and Cu7, the decrease with time was not significant. Its rate of copper loss was significantly higher than the ML Cu250 in the 1st year, but comparable after that. The TCu-220C had a similar rate to the Cu7 in the 1st year and significantly higher rates subsequently. The relevance of these findings to observed pregnancy rates and area of copper on the IUDs is discussed.

  5. MODIS/Terra Land Water Mask Derived from MODIS and SRTM L3 Global 250m SIN Grid V005

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS 250 m land-water mask (Short Name: MOD44W) is an improvement over the existing MODIS Nadir Bidirectional Reflectance Distribution Function (BRDF)-Adjusted...

  6. Structure function scaling in a Reλ = 250 turbulent mixing layer

    KAUST Repository

    Attili, Antonio

    2011-12-22

    A highly resolved Direct Numerical Simulation of a spatially developing turbulent mixing layer is presented. In the fully developed region, the flow achieves a turbulent Reynolds number Reλ = 250, high enough for a clear separation between large and dissipative scales, so for the presence of an inertial range. Structure functions have been calculated in the self-similar region using velocity time series and Taylor\\'s frozen turbulence hypothesis. The Extended Self-Similarity (ESS) concept has been employed to evaluate relative scaling exponents. A wide range of scales with scaling exponents and intermittency levels equal to homogeneous isotropic turbulence has been identified. Moreover an additional scaling range exists for larger scales; it is characterized by smaller exponents, similar to the values reported in the literature for flows with strong shear.

  7. 250 kA compact linear transformer driver for wire array z-pinch loads

    Directory of Open Access Journals (Sweden)

    S. C. Bott

    2011-05-01

    Full Text Available We present the application of a short rise (∼150  ns 250 kA linear transformer driver (LTD to wire array z-pinch loads for the first time. The generator is a modification of a previous driver in which a new conical power feed provides a low inductance coupling to wire loads. Performance of the new design using both short circuit and plasma loads is presented and discussed. The final design delivers ∼200  kA to a wire array load which is in good agreement with SCREAMER calculations using a simplified representative circuit. Example results demonstrate successful experiments using cylindrical, conical, and inverse wire arrays as well as previously published work on x-pinch loads.

  8. Impulsore Chresto. Opposition to Christianity in the Roman Empire c. 50-250 AD

    DEFF Research Database (Denmark)

    Engberg, Jakob

    Impulsore Chresto reassesses opposition to Christianity AD 50-250. The Roman authorities' persecutions have caught the attention of both the public, intrigued by martyrs, and scholars, arguing that executions were relatively rare. The latter is not challenged, but the executions are placed...... in context as the most dramatic aspect of a spectrum of opposition including rumors, polemic, harassment and accusations. Such opposition was taken for granted and rarely described. But studying the preserved texts on trials against Christians it appears that even here the roles of relatives, plaintiffs......, spectators or local officials were crucial. There were as many reasons for opposition as opponents, but some motives reappear in clusters: Christians were perceived as superstitious and ungodly, as endangering peace with the gods and social order....

  9. Evidence for general instability of past climate from a 250-KYR ice-core record

    DEFF Research Database (Denmark)

    Johnsen, Sigfus Johann; Clausen, Henrik Brink; Dahl-Jensen, Dorthe

    1993-01-01

     results1,2 from two ice cores drilled in central Greenland have revealed large, abrupt climate changes of at least regional extent during the late stages of the last glaciation, suggesting that climate in the North Atlantic region is able to reorganize itself rapidly, perhaps even within a few...... decades. Here we present a detailed stable-isotope record for the full length of the Greenland Ice-core Project Summit ice core, extending over the past 250 kyr according to a calculated timescale. We find that climate instability was not confined to the last glaciation, but appears also to have been...... marked during the last interglacial (as explored more fully in a companion paper3) and during the previous Saale-Holstein glacial cycle. This is in contrast with the extreme stability of the Holocene, suggesting that recent climate stability may be the exception rather than the rule. The last...

  10. Pierce-Wiggler electron beam system for 250 GHz GYRO-BWO: Final report

    International Nuclear Information System (INIS)

    Pirkle, D.R.; Alford, C.W.; Anderson, M.H.; Garcia, R.F.; Legarra, J.R.; Nordquist, A.L.

    1989-01-01

    This final report summarizes the design and performance of the VUW-8028 Pierce-Wiggler electron beam systems, which can be used to power high frequency gyro-BWO's. The operator's manual for this gyro-BWO beamstick is included as appendix A. Researchers at Lawrence Livermore National Laboratory (LLNL) are developing a gyro-BWO with a center frequency of 250 GHz, 6% bandwidth, and 10 kV peak output power. The gyro-BWO will be used to drive a free electron laser amplifier at LLNL. The electron beam requirements of the gyro-BWO application are: Small beam size, .100 inch at 2500 gauss axial magnetic field; a large fraction of the electron energy in rotational velocity; ability to vary the electrons' axial velocity easily, for electronic tuning; and low velocity spread i.e. little variation in the axial velocities of the electrons in the interaction region. 1 ref., 13 figs

  11. Shotgun metagenomics of 250 adult twins reveals genetic and environmental impacts on the gut microbiome

    DEFF Research Database (Denmark)

    Xie, Hailiang; Guo, Ruijin; Zhong, Huanzi

    2016-01-01

    The gut microbiota has been typically viewed as an environmental factor for human health. Twins are well suited for investigating the concordance of their gut microbiomes and decomposing genetic and environmental influences. However, existing twin studies utilizing metagenomic shotgun sequencing...... have included only a few samples. Here, we sequenced fecal samples from 250 adult twins in the TwinsUK registry and constructed a comprehensive gut microbial reference gene catalog. We demonstrate heritability of many microbial taxa and functional modules in the gut microbiome, including those...... associated with diseases. Moreover, we identified 8 million SNPs in the gut microbiome and observe a high similarity in microbiome SNPs between twins that slowly decreases after decades of living apart. The results shed new light on the genetic and environmental influences on the composition and function...

  12. Simulation of a 250 kW diesel fuel processor/PEM fuel cell system

    Science.gov (United States)

    Amphlett, J. C.; Mann, R. F.; Peppley, B. A.; Roberge, P. R.; Rodrigues, A.; Salvador, J. P.

    Polymer-electrolyte membrane (PEM) fuel cell systems offer a potential power source for utility and mobile applications. Practical fuel cell systems use fuel processors for the production of hydrogen-rich gas. Liquid fuels, such as diesel or other related fuels, are attractive options as feeds to a fuel processor. The generation of hydrogen gas for fuel cells, in most cases, becomes the crucial design issue with respect to weight and volume in these applications. Furthermore, these systems will require a gas clean-up system to insure that the fuel quality meets the demands of the cell anode. The endothermic nature of the reformer will have a significant affect on the overall system efficiency. The gas clean-up system may also significantly effect the overall heat balance. To optimize the performance of this integrated system, therefore, waste heat must be used effectively. Previously, we have concentrated on catalytic methanol-steam reforming. A model of a methanol steam reformer has been previously developed and has been used as the basis for a new, higher temperature model for liquid hydrocarbon fuels. Similarly, our fuel cell evaluation program previously led to the development of a steady-state electrochemical fuel cell model (SSEM). The hydrocarbon fuel processor model and the SSEM have now been incorporated in the development of a process simulation of a 250 kW diesel-fueled reformer/fuel cell system using a process simulator. The performance of this system has been investigated for a variety of operating conditions and a preliminary assessment of thermal integration issues has been carried out. This study demonstrates the application of a process simulation model as a design analysis tool for the development of a 250 kW fuel cell system.

  13. VIABILITAS DAN STABILITAS Lactobacillus Plantarum Mut7 FNCC 250 YANG DISUPLEMENTASIKAN DALAM SARI BUAH PEPAYA-NANAS SELAMA PENYIMPANAN [Viability and Stability of Lactobacillus Plantarum Mut 7 FNCC 250 Suplemented in Papaya-Pineapple Juice During Storage

    Directory of Open Access Journals (Sweden)

    Sri Hartati1

    2003-08-01

    Full Text Available Lactobacillus plantarum Mut7 FNCC 250 is an indigenous bacterium isolated from fermented food (“gatot” and a potential agent to reduce cholesterol. Study the on aplication of the bacterium as probiotic agent to food stuff is needed. The purpose of the study was to prepare formula of papaya-pineapple juice as probiotic carrier and to study the viability and capability of Lactobacillus plantarum Mut7 FNCC 250 to assimilate cholesterol during three months storage. Fruits juice was prepared with different formula and organoleptically tested. Selected juice formula was supplemented with Lactobacillus plantarum Mut7 FNCC 250 and stored in cool room (4-5 oC. During three month storage, the value of pH the product, cell viability and ability to assimilate cholesterol were evaluated. The result indicated that acceptable formula was papaya juice added with 25 % pineapple. Viability of Lactobacillus plantarum Mut7 FNCC 250 supplemented in papaya- pineapple juice was stable (decrease of < 1 log cycle, while the pH of the juice decreased after 3 month storage. The ability of Lactobacillus plantarum Mut7 FNCC 250 to assimilate cholesterol was stable within 2 months storage, but decreased after 3 months.

  14. Concentration of ions Co(II), Ni(II) at the Tokem-250 carboxylic cation exchange for catalysts development

    Science.gov (United States)

    Zharkova, Valentina; Bobkova, Ludmila; Brichkov, Anton; Kozik, Vladimir

    2017-11-01

    Sorption and catalytic properties of the cation exchanger are investigated. It was found that the Tokem-250 has a wide operating range of pH. The value of the effective ionization constant of the functional groups of the cation exchanger (pKa) is 6.59. The Tokem-250 cation exchanger exhibits selectivity to Ni2+ ions to Co2+ (D˜103). This is probably due to the stability of ion-exchange complexes detected by the method of diffuse reflectance electron spectroscopy (ESDD). According to these data, for Co2+ ions, in contrast to Ni2+, tetragonal distortion of octahedral coordination is characteristic, which has a positive effect on the stability of complexes with Co2+. To obtain spherical catalysts on the basis of Tokem-250, cobalt-containing samples of cation exchanger were used. The developed spherical materials have catalytic activity in the reactions of deep and partial oxidation of n-heptane.

  15. The 250AH/90A active lithium-thionyl chloride cell for Centaur-G application

    Science.gov (United States)

    Zolla, A. E.; Tura, D. D.

    1987-09-01

    A high rate active Li/SOCl2 cell was designed for use in a 28 volt, 250 amp-hour space battery system. The lithium battery is being considered as a replacement of its heavier silver-zinc counterpart on board the Centaur-G booster rocket which is used to launch payloads from the Space Shuttle cargo bay into deep-space. Basically a feasibility study, this development effort is demonstrating the ability of the lithium cell to deliver up to 90 amps safely at power densities of approximately 25 watts per pound. Test data on 4 prototype units is showing an energy density of 85 watt-hours per pound and 9.0 watt-hours/cu in. The cells tested typically delivered 280 to 300 amp-hours under ambient temperature test conditions using alternating continuous loads of 90, 55, and 20 amperes throughout life. Data from four cells tested are presented to demonstrate the capability of Li/SOCl2 technology for a C/3 discharge rate in active and hermetic cell units.

  16. Performances of 250 Amp-hr lithium/thionyl chloride cells

    Science.gov (United States)

    Goualard, Jacques

    1991-05-01

    A 250 Ah lithium thionyl chloride battery is being developed for a booster rocket engine. Extensive cell testing is running to evaluate functional and safety performances. Some results are presented. The lithium/thionyl chloride batteries were selected for their high energy density (low weight) as compared to other sources. The temperature of a lower weight item will be more sensitive to variations of internal and external heat fluxes than a heavier one. The use of high energy density L/TC batteries is subjected to stringent thermal environments to have benefit of energy density and to stay safe in any conditions. The battery thermal environment and discharge rate have to be adjusted to obtain the right temperature range at cell level, to have the maximum performances. Voltage and capacity are very sensitive to temperature. This temperature is the cell internal actual temperature during discharge. This temperature is directed by external thermal environment and by cell internal heat dissipation, i.e., cell actual voltage.

  17. A 250 GHz gyrotron with a 3 GHz tuning bandwidth for dynamic nuclear polarization.

    Science.gov (United States)

    Barnes, Alexander B; Nanni, Emilio A; Herzfeld, Judith; Griffin, Robert G; Temkin, Richard J

    2012-08-01

    We describe the design and implementation of a novel tunable 250 GHz gyrotron oscillator with >10 W output power over most of a 3 GHz band and >35 W peak power. The tuning bandwidth and power are sufficient to generate a >1 MHz nutation frequency across the entire nitroxide EPR lineshape for cross effect DNP, as well as to excite solid effect transitions utilizing other radicals, without the need for sweeping the NMR magnetic field. Substantially improved tunability is achieved by implementing a long (23 mm) interaction cavity that can excite higher order axial modes by changing either the magnetic field of the gyrotron or the cathode potential. This interaction cavity excites the rotating TE(₅,₂,q) mode, and an internal mode converter outputs a high-quality microwave beam with >94% Gaussian content. The gyrotron was integrated into a DNP spectrometer, resulting in a measured DNP enhancement of 54 on the membrane protein bacteriorhodopsin. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Conceptual study of a 250 kW planar SOFC system for CHP application

    Science.gov (United States)

    Fontell, E.; Kivisaari, T.; Christiansen, N.; Hansen, J.-B.; Pålsson, J.

    In August 2002, Wärtsilä Corporation and Haldor Topsøe A/S entered into a co-operation agreement to start joint development program within the planar SOFC technology. The development program aims to bring to the market highly efficient, clean and cost competitive fuel cell systems with power outputs above 200 kW for distributed power generation with CHP and for marine applications. In this study, the product concept for a 250 kW natural gas-fuelled atmospheric SOFC plant has been studied. The process has been calculated and optimised for high electrical efficiency. In the calculations, system efficiencies more than 55-85% (electrical co-generation) have been reached. The necessary balance of plant (BoP) components have been identified and the concept for grid connection has been defined. The BoP includes fuel and air supply, anode re-circulation, start-up steam, purge gas, exhaust gas heat recovery, back-up power, power electronics and control system. Based on the analysed system and component information, a conceptual design and cost break down structure for the product have been made. The cost breakdown shows that the stack, system control and power electronics are the major cost factors, while the remaining BoP equipment stands for a minor share of the manufacturing cost. Finally, the feasibility of the SOFC plants has been compared to gas engines.

  19. 250 um inner diameter hollow waveguide for Er:YAG laser radiation

    Science.gov (United States)

    Němec, Michal; Jelínková, Helena; Miyagi, Mitsunobu; Iwai, Katsumasa; Matsuura, Yuji

    2009-02-01

    Advanced application of Er:YAG laser radiation in medical treatment requires a suitable, very precise delivery of this light to a target. In some cases (urology, cardiology, or endodontic treatments), thin waveguides are needed. Therefore a preliminary investigation was conducted with 250/360 μm inner/outer diameter hollow glass waveguides. The waveguide has inner coating made from cyclic olefin polymer and silver layers. All delivery systems were simple and consisted of lens, protector, and the waveguide. The laser source was the Er:YAG system working in a free-running regime and generating radiation at 2.94 μm wavelength. For testing, output laser energy up to 100 mJ with a repetition rate of 1 Hz was chosen. The output laser spatial profile was approximately TEM00 mode, so the structure changes behind the delivery system were readily detected. The energy delivery characteristics were also checked, and the transmission reached 77%. The maximum input fluence into the waveguide was 200 mJ/cm2, and no significant damages to waveguides were observed after the measurements.

  20. Integrated tests of a high speed VXS switch card and 250 MSPS flash ADCs

    International Nuclear Information System (INIS)

    Dong, H.; Cuevas, C.; Curry, D.; Jastrzembski, E.; Barbosa, F.; Wilson, J.; Taylor, M.; Raydo, B.

    2008-01-01

    High trigger rate nuclear physics experiments proposed for the 12 GeV upgrade at the Thomas Jefferson National Accelerator Facility create a need for new high speed digital systems for energy summing. Signals from electronic detectors will be captured with the Jefferson Lab FADC module, which collects and processes data from 16 charged particle sensors with 10 or 12 bit resolution at 250 MHz sample rate. Up to sixteen FADC modules transfer energy information to a central energy summing module for each readout crate. The sums from the crates are combined to form a global energy sum that is used to trigger data readout for all modules. The Energy Sum module and FADC modules have been designed using the VITA-41 VME64 switched serial (VXS) standard. The VITA- 41 standard defines payload and switch slot module functions, and offers an elegant engineered solution for Multi-Gigabit serial transmission on a standard VITA-41 backplane. The Jefferson Lab Energy Sum module receives data serially at a rate of up to 6 Giga-bits per second from the FADC modules. Both FADC and Energy Sum modules have been designed and assembled and this paper describes the integrated tests using both high speed modules in unison

  1. Mapping irrigated lands at 250-m scale by merging MODIS data and National Agricultural Statistics

    Science.gov (United States)

    Pervez, Md Shahriar; Brown, Jesslyn F.

    2010-01-01

    Accurate geospatial information on the extent of irrigated land improves our understanding of agricultural water use, local land surface processes, conservation or depletion of water resources, and components of the hydrologic budget. We have developed a method in a geospatial modeling framework that assimilates irrigation statistics with remotely sensed parameters describing vegetation growth conditions in areas with agricultural land cover to spatially identify irrigated lands at 250-m cell size across the conterminous United States for 2002. The geospatial model result, known as the Moderate Resolution Imaging Spectroradiometer (MODIS) Irrigated Agriculture Dataset (MIrAD-US), identified irrigated lands with reasonable accuracy in California and semiarid Great Plains states with overall accuracies of 92% and 75% and kappa statistics of 0.75 and 0.51, respectively. A quantitative accuracy assessment of MIrAD-US for the eastern region has not yet been conducted, and qualitative assessment shows that model improvements are needed for the humid eastern regions where the distinction in annual peak NDVI between irrigated and non-irrigated crops is minimal and county sizes are relatively small. This modeling approach enables consistent mapping of irrigated lands based upon USDA irrigation statistics and should lead to better understanding of spatial trends in irrigated lands across the conterminous United States. An improved version of the model with revised datasets is planned and will employ 2007 USDA irrigation statistics.

  2. Utilization of a typical 250 kW TRIGA Mark II reactor at a University

    International Nuclear Information System (INIS)

    Villa, M.; Boeck, H.; Musilek, A.

    2007-01-01

    The 250 kW TRIGA Mark-II reactor operates since March 1962 at the Atominstitut Vienna/Austria. Its main tasks are nuclear education and training in the fields of neutron- and solid state physics, nuclear technology, reactor safety, radiochemistry, radiation protection and dosimetry, and low temperature physics and fusion research. Academic research is carried out by students in the above mentioned fields coordinated and supervised by about 70 staff members with the aim of a masters- or PhD degree in one of the above mentioned areas. During the past 15 years about 580 students graduated through the Atominstitut. In addition, the Atominstitut co-operates closely with the nearby located IAEA in research projects, coordinated research programs (CRP) and supplying expert services. Regular training courses are carried out for the IAEA for Safeguard Trainees, fellowship places are offered for scientists from developing countries and staff members carry out expert missions to research centres in Africa, Asia and South America. Special Nuclear Material (SNM) is stored for calibration purposes at the Atominstitut belonging to the IAEA. (author)

  3. MUSE-INGS ON AM1354-250: COLLISIONS, SHOCKS, AND RINGS

    Energy Technology Data Exchange (ETDEWEB)

    Conn, Blair C. [Gemini Observatory, Recinto AURA, Colina El Pino, Casilla 603, La Serena (Chile); Fogarty, L. M. R. [Sydney Institute for Astronomy, School of Physics, The University of Sydney, A28, Sydney, 2006 (Australia); Smith, Rory [Yonsei University, Graduate School of Earth System Sciences-Astronomy-Atmospheric Sciences, Yonsei-ro 50, Seoul 120-749 (Korea, Republic of); Candlish, Graeme N., E-mail: bconn@gemini.edu [Departamento de Astronomía, Universidad de Concepción, Casilla 160-C, Concepción (Chile)

    2016-03-10

    We present Multi Unit Spectroscopic Explorer observations of AM1354-250, confirming its status as a collisional ring galaxy that has recently undergone an interaction, creating its distinctive shape. We analyze the stellar and gaseous emission throughout the galaxy finding direct evidence that the gaseous ring is expanding with a velocity of ∼70 km s{sup −1} and that star formation is occurring primarily in H ii regions associated with the ring. This star formation activity is likely triggered by this interaction. We find evidence for several excitation mechanisms in the gas, including emission consistent with shocked gas in the expanding ring and a region of LINER-like emission in the central core of the galaxy. Evidence of kinematic disturbance in both the stars and gas, possibly also triggered by the interaction, can be seen in all of the velocity maps. The ring galaxy retains a weak spiral structure, strongly suggesting the progenitor galaxy was a massive spiral prior to the collision with its companion an estimated 140 ± 12 Myr ago.

  4. Heat transfer properties of polymer target shells at temperatures between 250K and 350K

    International Nuclear Information System (INIS)

    Honig, A.; Fan, Q.; Hsu, C.K.; Wei, X.

    1995-01-01

    The emissivities and accommodation coefficients for helium and deuterium gas were measured for polystyrene target shells from several production batches. The shells varied in wall thickness, diameter and surface conditions as viewed with an optical microscope. For emissivity measurements, it is desirable for the radiative heat transfer to dominate over conductive heat transfer via the surrounding gas and the sample (and thermometer) mount. This is achieved by maintaining very low gas pressure (free molecular conduction regime) and by a novel contact-less thermometric measurement, in which the temperature of the shell is determined from the strongly temperature-dependent shell outgassing rate. The accommodation coefficient is also obtained in the process. Emissivity and accommodation coefficient results are reported in the temperature range 250 - 350K. The values are very low, in the 0.01 range for the former, and 0.003 range for the latter, which augurs well for thermal stability after the shroud removal prior to a target shot. For measurements at lower temperatures (down to 4K), other contact-less thermometry methods are proposed, with electronic magnetic susceptibility shown to be very favorable. 6 refs., 7 figs., 1 tab

  5. [Jonathan Swift's asylum in Dublin--Ireland's introduction to institutional psychiatry 250 years ago].

    Science.gov (United States)

    Reuber, M

    1995-09-01

    250 years ago, the satirical writer and clergyman Jonathan Swift from Dublin (1667-1745) founded the first Irish lunatic asylum. Rejecting the theories put forward by the English philosopher Thomas Hobbes and the doctor Thomas Willis, he was influenced by the ideas of the Scottish doctor and the "enlightened" thinker John Locke. Swift's St. Patrick's Hospital did not, however, realise a new philosophical concept: architecture and therapeutic approach of the new institution were clearly modelled on the much older Hospital of St. Mary of Bethlehem ( = Bedlam). Despite its conservative conceptual basis, the first institution dedicated to the mentally ill and intellectually subnormal in Ireland became a starting point for the apparantly unstoppable expansion of the, at one time, most comprehensive asylum system in the world. After Swift's Hospital had been enlarged twice at the tax-payers' expense (1778, 1793), the administration decided to relieve the institution by erecting the Richmond Asylum (1810), the first public asylum in Ireland. When this establishment also became overcrowded, in 1817, legislation was passed which led to the establishment of the oldest system of public asylums in Europe.

  6. Design and fabrication of a 250 KW beam dump for LEHIPA

    International Nuclear Information System (INIS)

    Sawant, Y.; Agarwal, A.; Krishnagopal, S.; Singh, P.; Verma, Vishnu; Singh, R.K.; Kumawat, H.; Prasad, N.K.

    2013-01-01

    A 250 kW proton beam dump has been designed and developed for the Low Energy High Intensity Proton Accelerator (LEHIPA) project at BARC. This paper presents details of the design parameters, thermal analysis, and fabrication procedure and test results. Calculations of the heat flux distribution have been carried with the ICMC-1.0 code. The temperature distribution in the target and fluid, and heat flux at the solid-fluid interface has been evaluated using computational fluid dynamics code CFD ACE+. Effect of flow velocity on the temperature distribution has also been studied. The beam dump is in two sections: a conical inner section made of copper, on which the beam falls and deposits its energy, and an outer section that is the water cooling jacket. The copper parts were joined together by brazing. The outer cooling jacket has been designed and fabricated keeping in mind the cooling requirement of the inner target cone. The inner section has been vacuum checked to a vacuum level of 10 -6 Torr, and the outer section has been pressure tested to 6 bar. (author)

  7. 76 FR 41045 - Special Conditions; Gulfstream Aerospace LP (GALP) Model G250 Airplane, Design Roll-Maneuver...

    Science.gov (United States)

    2011-07-13

    ... issue a finding of regulatory adequacy under Sec. 611 of Public Law 92-574, the ``Noise Control Act of... with electronic flight controls as they relate to design roll-maneuver requirements. The applicable... G250 airplane is equipped with an electronic flight control system that provides control through the...

  8. of As at 170, 200, 250 and 300 K from the Bijvoet pairs of GaAs

    Indian Academy of Sciences (India)

    Unknown

    Experimental f″ of As at 170, 200, 250 and 300 K from the Bijvoet pairs of GaAs. G RAJA SUDHA, K VIMALA DEVI, D ARTHI, S PRASANNA SUBRAMANIAN,. N SRINIVASAN* and R SARAVANAN†. Department of Physics, Thiagarajar College, Madurai 625 009, India. †The Madura College, Madurai 625 011, India.

  9. 21 CFR 250.11 - Thyroid-containing drug preparations intended for treatment of obesity in humans.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Thyroid-containing drug preparations intended for... DRUGS Drugs Regarded as Misbranded § 250.11 Thyroid-containing drug preparations intended for treatment... number of drug preparations containing thyroid or thyrogenic substances in combination with central...

  10. 30 CFR 250.244 - What geological and geophysical (G&G) information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What geological and geophysical (G&G... Operations Coordination Documents (docd) § 250.244 What geological and geophysical (G&G) information must accompany the DPP or DOCD? The following G&G information must accompany your DPP or DOCD: (a) Geological...

  11. 30 CFR 250.214 - What geological and geophysical (G&G) information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What geological and geophysical (G&G... and Information Contents of Exploration Plans (ep) § 250.214 What geological and geophysical (G&G) information must accompany the EP? The following G&G information must accompany your EP: (a) Geological...

  12. Shiprock, AZ NM CO UT 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  13. MODIS/Aqua L2 Surface Reflectance, 5-Min Swath 250m, 500m, and 1km

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Aqua L2 Surface Reflectance, 5-Min Swath 250m, 500m, and 1km (MYD09). This product is computed from the MODIS Level 1B land bands 1, 2, 3, 4, 5, 6, and 7...

  14. 30 CFR 250.1742 - What other methods can I use to verify that a site is clear?

    Science.gov (United States)

    2010-07-01

    ... pattern of concentric circles or parallel lines spaced no more than 10 feet apart. (c) An ROV (remotely operated vehicle) ensure that the ROV camera records videotape over 100 percent of the appropriate grid area listed in § 250.1741(a) Ensure that the ROV uses a pattern of concentric circles or parallel lines...

  15. MODIS/Terra Near Real Time (NRT) Calibrated Radiances 5-Min L1B Swath 250m

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B Near Real Time (NRT) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88...

  16. MODIS/Aqua Near Real Time (NRT) Calibrated Radiances 5-Min L1B Swath 250m

    Data.gov (United States)

    National Aeronautics and Space Administration — The 250 meter MODIS Level 1B Near Real Time (NRT) data set contains calibrated and geolocated at-aperture radiances for 2 discrete bands located in the 0.62 to 0.88...

  17. Dalhart, NM OK TX CO 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  18. On-chip measurements of Brownian relaxation of magnetic beads with diameters from 10 nm to 250 nm

    DEFF Research Database (Denmark)

    Østerberg, Frederik Westergaard; Rizzi, Giovanni; Hansen, Mikkel Fougt

    2013-01-01

    We demonstrate the use of planar Hall effect magnetoresistive sensors for AC susceptibility measurements of magnetic beads with frequencies ranging from DC to 1 MHz. This wide frequency range allows for measuring Brownian relaxation of magnetic beads with diameters ranging from 10 nm to 250 nm...

  19. 78 FR 20326 - Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration-Human and Animal Food...

    Science.gov (United States)

    2013-04-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-0126] Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration--Human and Animal Food; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug...

  20. Heat flow diagrams with and without a deaerator for steam turbine plants with T-250/300-23.5 turbines

    Science.gov (United States)

    Valamin, A. E.; Kultyshev, A. Yu.; Shibaev, T. L.; Gol'dberg, A. A.; Stepanov, M. Yu.

    2016-11-01

    A T-250/300-240 turbine (currently known as T-250/300-23.5), which is operated at 31 steam turbine plants, is the largest in the world extraction turbine (by the heating extraction load) and one of the largest by the nominal capacity. All steam turbine plants equipped with T-250/300-23.5 turbines of different modifications are operated in large cities of Russia and the neighboring countries covering a significant part of the needs of cities for the electric power and almost fully supplying them with heat power. The design life of a significant part of the operated steam turbine plants of this family is either expired or almost expired. It refers to both the turbine unit (including a turbine and a generator) and the turbine plant equipment. For steam turbine plants equipped with T-250/300-23.5 turbines, which were initially designed and mounted for work with deaerators at electric power stations, the heat flow diagrams with and without a deaerator were compared. The main advantages and disadvantages of each scheme were shown. It was concluded that, for the newly constructed power units with supercritical steam parameters, it is preferable to use the heat flow diagram without a deaerator; for the upgraded blocks, if there are no objective reasons for the removal of a deaerator, it is recommended to keep the existing heat flow diagram of a turbine plant.

  1. 30 CFR 250.1741 - If I drag a trawl across a site, what requirements must I meet?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false If I drag a trawl across a site, what... Decommissioning Activities Site Clearance for Wells, Platforms, and Other Facilities § 250.1741 If I drag a trawl across a site, what requirements must I meet? If you drag a trawl across the site in accordance with...

  2. Covalently linked multimers of gold nanoclusters Au102(p-MBA)44 and Au∼250(p-MBA)n.

    Science.gov (United States)

    Lahtinen, Tanja; Hulkko, Eero; Sokołowska, Karolina; Tero, Tiia-Riikka; Saarnio, Ville; Lindgren, Johan; Pettersson, Mika; Häkkinen, Hannu; Lehtovaara, Lauri

    2016-11-10

    We present the synthesis, separation, and characterization of covalently-bound multimers of para-mercaptobenzoic acid (p-MBA) protected gold nanoclusters. The multimers were synthesized by performing a ligand-exchange reaction of a pre-characterized Au 102 (p-MBA) 44 nanocluster with biphenyl-4,4'-dithiol (BPDT). The reaction products were separated using gel electrophoresis yielding several distinct bands. The bands were analyzed by transmission electron microscopy (TEM) revealing monomer, dimer, and trimer fractions of the nanocluster. TEM analysis of dimers in combination with molecular dynamics simulations suggest that the nanoclusters are covalently bound via a disulfide bridge between BPDT molecules. The linking chemistry is not specific to Au 102 (p-MBA) 44 . The same approach yields multimers also for a larger monodisperse p-MBA-protected cluster of approximately 250 gold atoms, Au ∼250 (p-MBA) n . While the Au 102 (p-MBA) 44 is not plasmonic, the Au ∼250 (p-MBA) n nanocluster supports localized surface plasmon resonance (LSPR) at 530 nm. Multimers of the Au ∼250 (p-MBA) n exhibit additional transitions in their UV-vis spectrum at 630 nm and 810 nm, indicating the presence of hybridized LSPR modes. Well-defined structures and relatively small sizes make these systems excellent candidates for connecting ab initio theoretical studies and experimental quantum plasmonics. Moreover, our work opens new possibilities in the controlled synthesis of advanced monodisperse nanocluster superstructures.

  3. Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV

    DEFF Research Database (Denmark)

    Velte, Clara Marika; Hansen, Martin Otto Laver; Meyer, Knud Erik

    2009-01-01

    Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile. Measurements at two Reynolds numbers were analyzed; Re=0...

  4. Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV

    DEFF Research Database (Denmark)

    Velte, Clara Marika; Hansen, Martin Otto Laver; Meyer, Knud Erik

    2008-01-01

    Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile. Measurements at two Reynolds numbers were analyzed; Re=0...

  5. A 250-Mbit/s ring local computer network using 1.3-microns single-mode optical fibers

    Science.gov (United States)

    Eng, S. T.; Tell, R.; Andersson, T.; Eng, B.

    1985-01-01

    A 250-Mbit/s three-station fiber-optic ring local computer network was built and successfully demonstrated. A conventional token protocol was employed for bus arbitration to maximize the bus efficiency under high loading conditions, and a non-return-to-zero (NRS) data encoding format was selected for simplicity and maximum utilization of the ECL-circuit bandwidth.

  6. STUDY ON DISCHARGE HEAT UTILIZATION OF 250 MWe PCMSR TURBINE SYSTEM FOR DESALINATION USING MODIFIED MED

    Directory of Open Access Journals (Sweden)

    Andang Widiharto

    2015-03-01

    Full Text Available PCMSR (Passive Compact Molten Salt Reactor is one type of Advanced Nuclear Reactors. The PCMSR has benefit charasteristics of very efficient fuel use, high safety charecteristic as well as high thermodinamics efficiency. This is due to its breeding capability, inherently safe characteristic and totally passive safety system. The PCMSR design consists of three module, i.e. reactor module, turbine module and fuel management module. Analysis in performed by parametric calculation of the turbine system to calculate the turbine system efficiency and the hat available for desalination. After that the mass and energi balance of desalination process are calculated to calculate the amount of distillate produced and the amount of feed sea water needed. The turbine module is designed to be operated at maximum temperature cycle of 1373 K (1200 0C and minimum temperature cycle of 333 K (60 0K. The parametric calculation shows that the optimum turbine pressure ratio is 4.3 that gives the conversion efficiency of 56 % for 4 stages turbine and 4 stages compressor and equiped with recuperator. In this optimum condition, the 250 MWe PCMSR turbine system produces 196 MWth of waste heat with the temperature of cooling fluid in the range from 327 K (54 0C to 368 K (92 0C. This waste heat can be utilized for desalination. By using MMED desalination system, this waste heat can be used to produce fresh water (distillate from sea water feed. The amount of the destillate produced is 48663 ton per day by using 15 distillation effects. The performance ratio value is 2.8727 kg/MJ by using 15 distillation effects. Keywords: PCMSR, discharged heat, MMED desalination   PCMSR (Passive Compact Molten Salt Reactor merupakan salah satu tipe dari Reaktor Nuklir Maju. PCMSR memiliki keuntungan berupa penggunaan bahan bakar yang sangat efisisien, sifat keselamatan tinggi dan sekaligus efisiensi termodinamika yang tinggi. Hal ini disebabkan oleh kemampuan pembiakan bahan bakar, sifat

  7. 200 Jahre Darwin und 250 Jahre Theory of Moral Sentiments von Adam Smith

    Directory of Open Access Journals (Sweden)

    Gerold Bluemle

    2009-06-01

    Full Text Available The author emphasizes that 2009 must be remembered not only for the 200 birthday of Charles Darwin, but as well as the 250-year anniversary of Adam Smith’s “Theory of Moral Sentiments”. Proceeding from the fact that Darwin as well as Robert Malthus refer to a classical economist, it is investigated whether the analogies between Evolution Theory and Economy are justified. In both fields, the competition between the selfishly functioning units plays an important/dominating role. Smith, indeed, stresses in his “Theory of Moral Sentiments” apart from the ‘self-interest’ principle, the meaning of the principle of ‘Sympathy’ as a second in importance one which, as the author indicates, forms a prerequisite for the successful co-operation and harmony that the“invisible hand” establishes. The one-sided meaning of the “Wealth of Nations” as an eulogy of the egoism, that is the only motive, has its cause in the political interest of the rising liberalism. Finally, it is investigated whether Smith’s optimism for a free developing social harmony is justified nowadays, in relation to the rising centra lization and globalization. The author arrives at a conclusion that an economic regulation according to the “Freiburger Schule” views, which will be accomplished by the state and it will correspond with the previous developments, it will be in the position to setmeasures to the consequences of ethic deficit.Der Autor betont, dass 2009 neben dem 200. Geburtstag von Charles Darwin als zweitesJubiläum an das Erscheinen der „Theory of Moral Sentiments“ von Adam Smith vor250 Jahren zu erinnern ist. Ausgehend davon, dass sich Darwin selbst mit RobertMalthus auf einen Klassiker der Ökonomen berief, wird der Frage nachgegangeninwieweit Analogien zwischen der Evolutionstheorie und der Ökonomik gerechtfertigtsind. Bei beiden Ansätzen kommt ja dem Wettbewerb zwischen egoistisch handelndenWesen zentrale Bedeutung zu. Smith indessen

  8. Oversized 250 GHz Traveling Wave Tube with a Photonic Band-Gap Structure

    Science.gov (United States)

    Rosenzweig, Guy; Shapiro, Michael A.; Temkin, Richard J.

    2017-10-01

    The challenge in manufacturing traveling wave tubes (TWTs) at high frequencies is that the sizes of the structures scale with, and are much smaller than, the wavelength. We have designed and are building a 250 GHz TWT that uses an oversized structure to overcome fabrication and power handling issues that result from the small dimensions. Using a photonic band-gap (PBG) structure, we succeeded to design the TWT with a beam tunnel diameter of 0.72 mm. The circuit consists of metal plates with the beam tunnel drilled down their center. Twelve posts are protruding on one side of each plate in a triangular array and corresponding sockets are drilled on the other side. The posts of each plate are inserted into the sockets of an adjacent plate, forming a PBG lattice. The vacuum spacing between adjacent plates forms the `PBG cavity''. The full structure is a series of PBG coupled cavities, with microwave power coupling through the beam tunnel. The PBG lattice provides confinement of microwave power in each of the cavities and can be tuned to give the right amount of diffraction per cavity so that no sever is needed to suppress oscillations in the operating mode. CST PIC simulations predict over 38 dB gain with 67 W peak power, using a 30 kV, 310 mA electron beam, 0.6 mm in diameter. Research supported by the AFOSR Program on Plasma and Electro-Energetic Physics and by the NIH National Institute of Biomedical Imaging and Bioengineering.

  9. High lability of sexual system over 250 million years of evolution in morphologically conservative tadpole shrimps.

    Science.gov (United States)

    Mathers, Thomas C; Hammond, Robert L; Jenner, Ronald A; Zierold, Thorid; Hänfling, Bernd; Gómez, Africa

    2013-02-05

    Sexual system is a key factor affecting the genetic diversity, population structure, genome structure and the evolutionary potential of species. The sexual system androdioecy - where males and hermaphrodites coexist in populations - is extremely rare, yet is found in three crustacean groups, barnacles, a genus of clam shrimps Eulimnadia, and in the order Notostraca, the tadpole shrimps. In the ancient crustacean order Notostraca, high morphological conservatism contrasts with a wide diversity of sexual systems, including androdioecy. An understanding of the evolution of sexual systems in this group has been hampered by poor phylogenetic resolution and confounded by the widespread occurrence of cryptic species. Here we use a multigene supermatrix for 30 taxa to produce a comprehensive phylogenetic reconstruction of Notostraca. Based on this phylogenetic reconstruction we use character mapping techniques to investigate the evolution of sexual systems. We also tested the hypothesis that reproductive assurance has driven the evolution of androdioecy in Notostraca. Character mapping analysis showed that sexual system is an extremely flexible trait within Notostraca, with repeated shifts between gonochorism and androdioecy, the latter having evolved a minimum of five times. In agreement with the reproductive assurance hypothesis androdioecious notostracans are found at significantly higher latitudes than gonochoric ones indicating that post glacial re-colonisation may have selected for the higher colonisation ability conferred by androdioecy. In contrast to their conserved morphology, sexual system in Notostraca is highly labile and the rare reproductive mode androdioecy has evolved repeatedly within the order. Furthermore, we conclude that this lability of sexual system has been maintained for at least 250 million years and may have contributed to the long term evolutionary persistence of Notostraca. Our results further our understanding of the evolution of androdioecy

  10. High lability of sexual system over 250 million years of evolution in morphologically conservative tadpole shrimps

    Directory of Open Access Journals (Sweden)

    Mathers Thomas C

    2013-02-01

    Full Text Available Abstract Background Sexual system is a key factor affecting the genetic diversity, population structure, genome structure and the evolutionary potential of species. The sexual system androdioecy – where males and hermaphrodites coexist in populations – is extremely rare, yet is found in three crustacean groups, barnacles, a genus of clam shrimps Eulimnadia, and in the order Notostraca, the tadpole shrimps. In the ancient crustacean order Notostraca, high morphological conservatism contrasts with a wide diversity of sexual systems, including androdioecy. An understanding of the evolution of sexual systems in this group has been hampered by poor phylogenetic resolution and confounded by the widespread occurrence of cryptic species. Here we use a multigene supermatrix for 30 taxa to produce a comprehensive phylogenetic reconstruction of Notostraca. Based on this phylogenetic reconstruction we use character mapping techniques to investigate the evolution of sexual systems. We also tested the hypothesis that reproductive assurance has driven the evolution of androdioecy in Notostraca. Results Character mapping analysis showed that sexual system is an extremely flexible trait within Notostraca, with repeated shifts between gonochorism and androdioecy, the latter having evolved a minimum of five times. In agreement with the reproductive assurance hypothesis androdioecious notostracans are found at significantly higher latitudes than gonochoric ones indicating that post glacial re-colonisation may have selected for the higher colonisation ability conferred by androdioecy. Conclusions In contrast to their conserved morphology, sexual system in Notostraca is highly labile and the rare reproductive mode androdioecy has evolved repeatedly within the order. Furthermore, we conclude that this lability of sexual system has been maintained for at least 250 million years and may have contributed to the long term evolutionary persistence of Notostraca. Our

  11. A 250 plastome phylogeny of the grass family (Poaceae): topological support under different data partitions

    Science.gov (United States)

    Burke, Sean V.; Wysocki, William P.; Clark, Lynn G.

    2018-01-01

    The systematics of grasses has advanced through applications of plastome phylogenomics, although studies have been largely limited to subfamilies or other subgroups of Poaceae. Here we present a plastome phylogenomic analysis of 250 complete plastomes (179 genera) sampled from 44 of the 52 tribes of Poaceae. Plastome sequences were determined from high throughput sequencing libraries and the assemblies represent over 28.7 Mbases of sequence data. Phylogenetic signal was characterized in 14 partitions, including (1) complete plastomes; (2) protein coding regions; (3) noncoding regions; and (4) three loci commonly used in single and multi-gene studies of grasses. Each of the four main partitions was further refined, alternatively including or excluding positively selected codons and also the gaps introduced by the alignment. All 76 protein coding plastome loci were found to be predominantly under purifying selection, but specific codons were found to be under positive selection in 65 loci. The loci that have been widely used in multi-gene phylogenetic studies had among the highest proportions of positively selected codons, suggesting caution in the interpretation of these earlier results. Plastome phylogenomic analyses confirmed the backbone topology for Poaceae with maximum bootstrap support (BP). Among the 14 analyses, 82 clades out of 309 resolved were maximally supported in all trees. Analyses of newly sequenced plastomes were in agreement with current classifications. Five of seven partitions in which alignment gaps were removed retrieved Panicoideae as sister to the remaining PACMAD subfamilies. Alternative topologies were recovered in trees from partitions that included alignment gaps. This suggests that ambiguities in aligning these uncertain regions might introduce a false signal. Resolution of these and other critical branch points in the phylogeny of Poaceae will help to better understand the selective forces that drove the radiation of the BOP and PACMAD

  12. Statistics and scaling of turbulence in a spatially developing mixing layer at Reλ = 250

    KAUST Repository

    Attili, Antonio

    2012-03-21

    The turbulent flow originating from the interaction between two parallel streams with different velocities is studied by means of direct numerical simulation. Rather than the more common temporal evolving layer, a spatially evolving configuration, with perturbed laminar inlet conditions is considered. The streamwise evolution and the self-similar state of turbulence statistics are reported and compared to results available in the literature. The characteristics of the transitional region agree with those observed in other simulations and experiments of mixing layers originating from laminar inlets. The present results indicate that the transitional region depends strongly on the inlet flow. Conversely, the self-similar state of turbulent kinetic energy and dissipation agrees quantitatively with those in a temporal mixing layer developing from turbulent initial conditions [M. M. Rogers and R. D. Moser, “Direct simulation of a self-similar turbulent mixing layer,” Phys. Fluids6, 903 (1994)]. The statistical features of turbulence in the self-similar region have been analysed in terms of longitudinal velocity structure functions, and scaling exponents are estimated by applying the extended self-similarity concept. In the small scale range (60 < r/η < 250), the scaling exponents display the universal anomalous scaling observed in homogeneous isotropic turbulence. The hypothesis of isotropy recovery holds in the turbulent mixing layer despite the presence of strong shear and large-scale structures, independently of the means of turbulence generation. At larger scales (r/η > 400), the mean shear and large coherent structures result in a significant deviation from predictions based on homogeneous isotropic turbulence theory. In this second scaling range, the numerical values of the exponents agree quantitatively with those reported for a variety of other flows characterized by strong shear, such as boundary layers, as well as channel and wake flows.

  13. Study for optimization of a 60 Co industrial irradiator of 250 k Ci

    International Nuclear Information System (INIS)

    Pina V, G.

    1995-01-01

    This work presents results of a benchmark between calculated and experimental absorbed dose values for a typical product, in a 60 Co industrial irradiator, located at ININ, Mexico. The goal of this work is to reach a ± 10 % approximation between both values. ININ 60 Co industrial irradiator is a two level, two layer system with overlapping product configuration, 56 irradiation positions with an activity of around 250 k Ci. Calculated values were obtained by QAD-CGGP code. This code uses a point kernel technique, build-up factors fitting was done by geometrical progression and combinatorial geometry was used for 3 D system description. Main code modifications were related with source simulation by punctual sources and energy spectrum (16 energy groups) and anisotropic emission were also considered. Experimental data were obtained from routine dosimetry which was done with red acrylic pellets; they were irradiated together the product in predetermined positions, for 36 maximum and minimum absorbed dose values. Typical product was polypropylene Petri dish packages, apparent density 0.13 g/cm 3 . It was chosen because regular geometry (2 packages per full irradiator container) and enough amount for considering homogeneous loading inside irradiation chamber. Required minimum dose was 15 kGy. Results showed a 8% variation between calculated and experimental values for maximum absorbed dose (18.2 kGy vs 16.8 kGy) and 3 % variation for minimum absorbed dose (13.8 kGy vs 14.3 kGy); these results fixed with the original proposal. (Author)

  14. Staining of proteins in gels with Coomassie G-250 without organic solvent and acetic acid.

    Science.gov (United States)

    Lawrence, Ann-Marie; Besir, H Uuml Seyin

    2009-08-14

    In classical protein staining protocols using Coomassie Brilliant Blue (CBB), solutions with high contents of toxic and flammable organic solvents (Methanol, Ethanol or 2-Propanol) and acetic acid are used for fixation, staining and destaining of proteins in a gel after SDS-PAGE. To speed up the procedure, heating the staining solution in the microwave oven for a short time is frequently used. This usually results in evaporation of toxic or hazardous Methanol, Ethanol or 2-Propanol and a strong smell of acetic acid in the lab which should be avoided due to safety considerations. In a protocol originally published in two patent applications by E.M. Wondrak (US2001046709 (A1), US6319720 (B1)), an alternative composition of the staining solution is described in which no organic solvent or acid is used. The CBB is dissolved in bidistilled water (60-80 mg of CBB G-250 per liter) and 35 mM HCl is added as the only other compound in the staining solution. The CBB staining of the gel is done after SDS-PAGE and thorough washing of the gel in bidistilled water. By heating the gel during the washing and staining steps, the process can be finished faster and no toxic or hazardous compounds are evaporating. The staining of proteins occurs already within 1 minute after heating the gel in staining solution and is fully developed after 15-30 min with a slightly blue background that is destained completely by prolonged washing of the stained gel in bidistilled water, without affecting the stained protein bands.

  15. Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid

    Science.gov (United States)

    Lawrence, Ann-Marie; Besir, Hüseyin

    2009-01-01

    In classical protein staining protocols using Coomassie Brilliant Blue (CBB), solutions with high contents of toxic and flammable organic solvents (Methanol, Ethanol or 2-Propanol) and acetic acid are used for fixation, staining and destaining of proteins in a gel after SDS-PAGE. To speed up the procedure, heating the staining solution in the microwave oven for a short time is frequently used. This usually results in evaporation of toxic or hazardous Methanol, Ethanol or 2-Propanol and a strong smell of acetic acid in the lab which should be avoided due to safety considerations. In a protocol originally published in two patent applications by E.M. Wondrak (US2001046709 (A1), US6319720 (B1)), an alternative composition of the staining solution is described in which no organic solvent or acid is used. The CBB is dissolved in bidistilled water (60-80mg of CBB G-250 per liter) and 35 mM HCl is added as the only other compound in the staining solution. The CBB staning of the gel is done after SDS-PAGE and thorough washing of the gel in bidistilled water. By heating the gel during the washing and staining steps, the process can be finished faster and no toxic or hazardous compunds are evaporating. The staining of proteins occurs already within 1 minute after heating the gel in staining solution and is fully developed after 15-30 min with a slightly blue background that is destained completely by prolonged washing of the stained gel in bidistilled water, without affecting the stained protein bands. PMID:19684570

  16. Aspectos generales de la Ley número 17.250 de relaciones de consumo

    Directory of Open Access Journals (Sweden)

    Teresita Mercader Pizzorno

    2014-11-01

    Full Text Available El 20 de setiembre de 1999 el Poder Ejecutivo de nuestro país promulgó una ley, la 17.189, por la que se establecían normas destinadas a regular las relaciones de consumo, la que fue publicada en el Diario Oficial del 30 de setiembre de 1999.Su último art., el 52, establecía que comenzaría a regir a los nueve meses contados desde su publicación. Por tanto, la fecha de entrada en vigencia fue ello. de julio del presente año.Sin embargo, un error acaecido en el proceso de elaboración determinó que, en forma prácticamente inmediata a su entrada en vigor, se procediera a elaborar un proyecto de ley para derogarla y sustituirla por otra, que fue promulgada el 11 de agosto de 2000 con el número 17.250 Y fue reglamentada por decreto 244/2000 del 23 de agosto del mismo año.El texto de la nueva leyes prácticamente igual al de la anterior, excepto, claro está, el artículo 33 que es el que había sido aprobado en el trámite de sanción en una y otra Cámara con distinto texto,También en la segunda ley se sustituyó el artículo 52 antes citado (...

  17. A role for the septation initiation network in septum assembly revealed by genetic analysis of sid2-250 suppressors.

    Science.gov (United States)

    Jin, Quan-Wen; Zhou, Mian; Bimbo, Andrea; Balasubramanian, Mohan K; McCollum, Dannel

    2006-04-01

    In the fission yeast Schizosaccharomyces pombe the septation initiation network (SIN) is required for stabilization of the actomyosin ring in late mitosis as well as for ring constriction and septum deposition. In a genetic screen for suppressors of the SIN mutant sid2-250, we isolated a mutation, ace2-35, in the transcription factor Ace2p. Both ace2Delta and ace2-35 show defects in cell separation, and both can rescue the growth defects of some SIN mutants at low restrictive temperatures, where the SIN single mutants lyse at the time of cytokinesis. By detailed analysis of the formation and constriction of the actomyosin ring and septum in the sid2-250 mutant at low restrictive temperatures, we show that the lysis phenotype of the sid2-250 mutant is likely due to a weak cell wall and septum combined with enzymatic activity of septum-degrading enzymes. Consistent with the recent findings that Ace2p controls transcription of genes involved in cell separation, we show that disruption of some of these genes can also rescue sid2-250 mutants. Consistent with SIN mutants having defects in septum formation, many SIN mutants can be rescued at the low restrictive temperature by the osmotic stabilizer sorbitol. The small GTPase Rho1 is known to promote cell wall formation, and we find that Rho1p expressed from a multi-copy plasmid can also rescue sid2-250 at the low restrictive temperature. Together these results suggest that the SIN has a role in promoting proper cell wall formation at the division septa.

  18. Large Carbon Uptake by an Unmanaged 250 year-old Deciduous Forest in Central Germany

    Science.gov (United States)

    Knohl, A.; Schulze, E.; Kolle, O.; Buchmann, N.

    2002-12-01

    Unmanaged forests at a late stage of successional development are considered to be insignificant as carbon sinks, since in theory, assimilation is thought to be balanced by respiration. However, little experimental evidence for this hypothesis exists so far for forests at the ecosystem scale. Therefore, we performed continuous eddy covariance measurements of carbon dioxide over an unmanaged beech forest in the Hainich National Park in Central Germany as part of the EU project CARBOEUROFLUX. This forest shows typical characteristics of an advanced forest with large dead wood pools, a diverse stand structure and a wide tree age class distribution, up to 250 years. Large carbon uptake rates up to 40 μmol m-2 s-1 were measured in summer while typical nighttime carbon losses were at around 4 μmol m-2 s-1. Consequently, this forest was a large carbon sink over two years, with 528 g C m-2 yr-1 in 2000 and 496 g C m-2 yr-1 in 2001. Daytime summer fluxes were strongly controlled by photosynthetic photon flux density (R2 = 0.8 - 0.9), with minor effects of the ratio of diffuse to total downward radiation or the vapor pressure deficit. Nighttime CO2 fluxes were mainly controlled by soil temperature (R2 = 0.7) and soil moisture. In addition, high nighttime CO2 fluxes (4 - 6 μmol m-2 s-1) were found directly before and during bud break in spring as well as just after leaf fall of both years (2000 and 2001), reflecting stand physiology corresponding to phenological changes, independent of soil temperature. To increase confidence in these unexpected high carbon sinks, the usual quality checks such as stationarity tests and u* correction were performed. In addition, measurements of wind profiles at 5 heights within the canopy revealed a decoupling of above and below canopy air flow under conditions of low u* (u* < 0.3 m s-1), probably indicating down slope drainage. With this new independent method, we derived a u* threshold value for appropriately excluding nighttime eddy

  19. Interpreting 250m Moderate Resolution Imaging Spectroradiometer Vegetation Indices in the Colorado Plateau, USA

    Science.gov (United States)

    Hamar, M.; White, M.; Lauver, C.; Garman, S.

    2006-12-01

    Semi-arid ecosystems, which are inherently vulnerable to small changes in the amount and distribution of precipitation, are frequently co-located with extensive human habitations and vulnerable species distributions. Important societal considerations identified by GEOSS, such as human health and well-being, ecological services, environmental protection, genetic resources, and disaster risk reduction and mitigation, may be under particular strain from invasive species, demographic changes, and/or climate change in semi-arid ecosystems. Satellite-based remote sensing may therefore be an important tool for monitoring the status of semi-arid ecosystems and habitats. Yet to date, the ability of current generation sensors, such as the Moderate Resolution Imaging Spectroradiometer (MODIS), to accurately represent within-season phenological variability in semi-arid ecosystems a crucial precursor for long-term monitoring is largely unknown. Several programs worldwide seek information on this relationship. As part of one such effort, the Vital Signs Monitoring program for the National Park Service (NPS), we evaluated the ability of the MODIS 250m Normalized Difference Vegetation Index (NDVI), Enhanced Vegetation Index (EVI), and red, near infra-red, and blue channels to represent relative changes in ground-measured vegetation structure. Using an AccuPAR LP-80 PAR/LAI Ceptometer, LAI-2000 Plant Canopy Analyzer, and First Growth digital camera, we sampled plant area index (PAI) and green fractional cover (GFC) at 4 sites along a bioclimatic gradient in the Colorado Plateau, USA, representing semi-arid woodland, mixed grassland/shrubland, and grassland plant functional types. In 14 visits from June 2005 to October 2005, we intensively sampled each site at a spatial resolution directly comparable to 4 MODIS pixels. At each site, PAI was always less than 1.0 and often less than 0.4 and GFC was rarely greater than 5%. Likely due to low plant cover and instrument noise, correlation

  20. Current status and technical description of Chinese 2 x 250 MWth HTR-PM demonstration plant

    International Nuclear Information System (INIS)

    Zhang Zuoyi; Wu Zongxin; Wang Dazhong; Xu Yuanhui; Sun Yuliang; Li Fu; Dong Yujie

    2009-01-01

    After the nuclear accidents of Three Mile Island and Chernobyl the world nuclear community made great efforts to increase research on nuclear reactors and to develop advanced nuclear power plants with much improved safety features. Following the successful construction and a most gratifying operation of the 10 MW th high-temperature gas-cooled test reactor (HTR-10), the Institute of Nuclear and New Energy Technology (INET) of Tsinghua University has developed and designed an HTR demonstration plant, called the HTR-PM (high-temperature-reactor pebble-bed module). The design, having jointly been carried out with industry partners from China and in collaboration of experts worldwide, closely follows the design principles of the HTR-10. Due to intensive engineering and R and D efforts since 2001, the basic design of the HTR-PM has been finished while all main technical features have been fixed. A Preliminary Safety Analysis Report (PSAR) has been compiled. The HTR-PM plant will consist of two nuclear steam supply system (NSSS), so called modules, each one comprising of a single zone 250 MW th pebble-bed modular reactor and a steam generator. The two NSSS modules feed one steam turbine and generate an electric power of 210 MW. A pilot fuel production line will be built to fabricate 300,000 pebble fuel elements per year. This line is closely based on the technology of the HTR-10 fuel production line. The main goals of the project are two-fold. Firstly, the economic competitiveness of commercial HTR-PM plants shall be demonstrated. Secondly, it shall be shown that HTR-PM plants do not need accident management procedures and will not require any need for offsite emergency measures. According to the current schedule of the project the completion date of the demonstration plant will be around 2013. The reactor site has been evaluated and approved; the procurement of long-lead components has already been started. After the successful operation of the demonstration plant

  1. SoilGrids250m: Global gridded soil information based on machine learning.

    Directory of Open Access Journals (Sweden)

    Tomislav Hengl

    Full Text Available This paper describes the technical development and accuracy assessment of the most recent and improved version of the SoilGrids system at 250m resolution (June 2016 update. SoilGrids provides global predictions for standard numeric soil properties (organic carbon, bulk density, Cation Exchange Capacity (CEC, pH, soil texture fractions and coarse fragments at seven standard depths (0, 5, 15, 30, 60, 100 and 200 cm, in addition to predictions of depth to bedrock and distribution of soil classes based on the World Reference Base (WRB and USDA classification systems (ca. 280 raster layers in total. Predictions were based on ca. 150,000 soil profiles used for training and a stack of 158 remote sensing-based soil covariates (primarily derived from MODIS land products, SRTM DEM derivatives, climatic images and global landform and lithology maps, which were used to fit an ensemble of machine learning methods-random forest and gradient boosting and/or multinomial logistic regression-as implemented in the R packages ranger, xgboost, nnet and caret. The results of 10-fold cross-validation show that the ensemble models explain between 56% (coarse fragments and 83% (pH of variation with an overall average of 61%. Improvements in the relative accuracy considering the amount of variation explained, in comparison to the previous version of SoilGrids at 1 km spatial resolution, range from 60 to 230%. Improvements can be attributed to: (1 the use of machine learning instead of linear regression, (2 to considerable investments in preparing finer resolution covariate layers and (3 to insertion of additional soil profiles. Further development of SoilGrids could include refinement of methods to incorporate input uncertainties and derivation of posterior probability distributions (per pixel, and further automation of spatial modeling so that soil maps can be generated for potentially hundreds of soil variables. Another area of future research is the development of

  2. Does the Loss of ARID1A (BAF-250a Expression in Endometrial Clear Cell Carcinomas Have Any Clinicopathologic Significance? A Pilot Assessment

    Directory of Open Access Journals (Sweden)

    Oluwole Fadare, Idris L. Renshaw, Sharon X. Liang

    2012-01-01

    Full Text Available SWI/SNF chromatin-modification complexes use the energy of ATP hydrolysis to remodel nucleosomes and to affect transcription and several cellular processes. Accordingly, their loss of function has been associated with malignant transformation. ARID1A (the expression of whose product, BAF250a, a key complex component, is lost when mutated has recently been identified as a tumor suppressor gene that is mutated in 46-57% of ovarian clear cell carcinoma (CCC. The purposes of this study are to assess the frequency of loss of BAF250a expression in endometrial CCC and whether this loss has any discernable clinicopathologic implications. 34 endometrial carcinomas with a CCC component (including 22 pure CCC, 8 mixed carcinomas with a 10% CCC component, and 4 carcinosarcomas with a CCC epithelial component, were evaluated by immunohistochemistry using a monoclonal antibody directed against the human BAF250a protein. 5 (22.7% of the 22 pure CCC were entirely BAF250a negative, whereas the remainder showed diffuse immunoreactivity. None of 4 carcinosarcomas and only 1 (12.5% of the 8 mixed carcinomas were BAF250a negative. There was no discernable relationship between BAF250a immunoreactivity status and tumor architectural patterns (solid, papillary or tubulocystic areas or cell type (flat, hobnail or polygonal. Of the 22 patients with pure CCC, 14, 2, 3, and 3 were International Federation of Gynecology and Obstetrics stages 1, II, III and IV respectively. Interestingly, all 5 BAF250a negative cases were late stage [stages III or IV] as compared with 1 of 17 BAF250a positive cases (p=0.0002. Thus, 83% (5/6 of all late stage cases were BAF250a [-], as compared with 0 (0% of the 16 early stage (I or II cases (p=.0002. BAF250a negative and positive cases did not show any statistically significant difference regarding patient age and frequency of lymphovascular invasion or myometrial invasion. As may be anticipated from the concentration of late stage cases in

  3. 250 kV 6 mA compact Cockcroft-Walton high-voltage power supply.

    Science.gov (United States)

    Ma, Zhan-Wen; Su, Xiao-Dong; Lu, Xiao-Long; Wei, Zhen; Wang, Jun-Run; Huang, Zhi-Wu; Miao, Tian-You; Su, Tong-Ling; Yao, Ze-En

    2016-08-01

    A compact power supply system for a compact neutron generator has been developed. A 4-stage symmetrical Cockcroft-Walton circuit is adopted to produce 250 kV direct current high-voltage. A 2-stage 280 kV isolation transformer system is used to drive the ion source power supply. For a compact structure, safety, and reliability during the operation, the Cockcroft-Walton circuit and the isolation transformer system are enclosed in an epoxy vessel containing the transformer oil whose size is about ∅350 mm × 766 mm. Test results indicate that the maximum output voltage of the power supply is 282 kV, and the stability of the output voltage is better than 0.63% when the high voltage power supply is operated at 250 kV, 6.9 mA with the input voltage varying ±10%.

  4. Post-irradiation behaviour of defected UO2 fuel elements in air at 220-250 degrees C

    International Nuclear Information System (INIS)

    Novak, J.; Hastings, I.J.

    1983-08-01

    We have heated in air irradiated CANDU UO 2 fuel elements with and without deliberately-induced defects. The temperature range was 220-250 degrees C for times up to 685 h. Pre-test burnup was about 190 MW.h/kg U (8000 MW.d/TeU) at a maximum linear power of 45 kW/m. Elements with single and multiple defects maintained reasonable dimensional stability up to 685 h at 220 and 230 degrees C, consistent with fuel oxidation primarily to U 3 O 7 . In this temperature range, there was no significant difference in response of defected elements with different power histories and cooling times. Irradiated fuel showed rates of weight increases up to 50 times greater than those for unirradiated fuel. Elements with single and multiple defects showed significant diametral increases and severe sheath splitting after about 200 h at 250 degrees C, consistent with fuel oxidation primarily to U 3 O 8

  5. Twelve-month comparative multicenter study of the TCu 380A and ML 250 intrauterine devices in Bangkok, Thailand.

    Science.gov (United States)

    Reinprayoon, D; Gilmore, C; Farr, G; Amatya, R

    1998-10-01

    The long-term effectiveness of the copper-bearing intrauterine device (IUD) has been documented. This paper reports 12-month results from a multiyear comparative study of the Copper T (TCu) 380A and Multiload (ML) 250 IUD in Bangkok, Thailand, among 1396 women. Continuation of the assigned IUD was relatively high after 12 months of use, with continuation rates of 90.17 and 87.54 per 100 women, respectively. Whereas the accidental pregnancy rate was higher for the ML 250 IUD than for the TCu 380A IUD (1.0 and 0.2 per 100 women, respectively), this difference was not considered statistically significant (p TCu 380A IUD (4.61 and 2.40 per 100 women, respectively, p = 0.05).

  6. Antigenic differentiation of classical swine fever vaccinal strain PAV-250 from other strains, including field strains from Mexico.

    Science.gov (United States)

    Mendoza, Susana; Correa-Giron, Pablo; Aguilera, Edgar; Colmenares, Germán; Torres, Oscar; Cruz, Tonatiuh; Romero, Andres; Hernandez-Baumgarten, Eliseo; Ciprián, Abel

    2007-10-10

    Twenty-nine classical swine fever virus (CSFv) strains were grown in the PK15 or SK6 cell lines. Antigenic differentiation studies were performed using monoclonal antibodies (McAbs), produced at Lelystad (CDI-DLO), The Netherlands. The monoclonals which were classified numerically as monoclonals 2-13. Epitope map patterns that resulted from the reactivity with McAbs were found to be unrelated to the pathogenicity of the viruses studied. Antigenic determinants were recognized by McAbs 5 and 8, were not detected in some Mexican strains; however, sites for McAb 6 were absent in all strains. The PAV-250 vaccine strain was recognized by all MAbs, except by MAb 6. Furthermore, the Chinese C-S vaccine strain was found to be very similar to the GPE(-) vaccine. None of the studied Mexican vaccines or field strains was found to be similar to the PAV-250 vaccine strain.

  7. Pressure and temperature dependence of excess enthalpies of methanol + tetraethylene glycol dimethyl ether and methanol + polyethylene glycol dimethyl ether 250

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, E.R.; Coxam, J.Y.; Fernandez, J.; Grolier, J.P.E.

    1999-12-01

    The excess molar enthalpies at 323.15 K, 373.15 K, and 423.15 K, at 8 MPa, are reported for the binary mixtures methanol + tetraethylene glycol dimethyl ether (TEGDME) and methanol + poly(ethylene glycol) dimethyl ether 250 (PEGDME 250). Excess molar enthalpies were determined with a Setaram C-80 calorimeter equipped with a flow mixing cell. For both systems, the excess enthalpies are positive over the whole composition range, increasing with temperature. The H{sup E}(x) curves are slightly asymmetrical, and their maxima are skewed toward the methanol-rich region. The excess enthalpies slightly change with the pressure, the sign of this change being composition-dependent. In the case of mixtures with TEGDME, the experimental H{sup E} values have been compared with those predicted with the Gmehling et al. version of UNIFAC (Dortmund) and the Nitta-Chao and DISQUAC group contribution models.

  8. Calculation of proton induced reaction on 209Bi in energy region from 7 to 250 MeV

    International Nuclear Information System (INIS)

    Gao Bo; Sun Xiuquan

    2000-01-01

    Cross sections of p + 209 Bi reaction are calculated from 7 to 250 MeV based on various nuclear reaction models, i.e., the optical model, evaporation model, exciton model, as well as the direct reaction theory. The comparison of the calculated results with the experimental data shows that author's calculations are quite reasonable. Moreover, excitation functions for the reactions producing some long-lived radioactive nuclei and neutron multiplicity are predicted

  9. Straight and chopped DC performance data for a reliance EV-250AT motor with a General Electric EV-1 controller

    Science.gov (United States)

    Edie, P. C.

    1981-01-01

    Straight and chopped DC motor performances for a Reliance EV-250AT motor with an EV-1 controller were examined. Effects of motor temperature and operating voltage are shown. It is found that the maximum motor efficiency is approximately 85% at low operating temperatures in the straight DC mode. Chopper efficiency is 95% under all operating conditions. For equal speeds, the motor operated in the chopped mode develops slightly more torque and draws more current than it does in the straight DC mode.

  10. Collective flow in central Au-Au collisions at 150, 250 and 400 A MeV

    OpenAIRE

    Nemeth, Judit; Papp, Gabor

    1997-01-01

    Radial collective flow and thermalization are studied in gold on gold collisions at 150, 250 and 400 A MeV bombarding energies with a relativistically covariant formulation of a QMD code. We find that radial flow and "thermal" energies calculated for all the charged fragments agree reasonably with the experimental values. The experimental hardware filter at small angles used in the FOPI experiments at higher energies selects mainly the thermalized particles.

  11. Complete Set of Deuteron Analyzing Powers for dp Elastic Scattering at 250 MeV/nucleon and Three Nucleon Forces

    Directory of Open Access Journals (Sweden)

    Shimizu Y.

    2010-04-01

    Full Text Available Measurements of a complete set of deuteron analyzing powers (iT11, T20, T21, T22 for elastic deuteron–proton scattering at 250 MeV/nucleon have been performed with polarized deuteron beams at RIKEN RI Beam Factory. The obtained data are compared with the Faddeev calculations based on the modern nucleon–nucleon forces together with the Tucson-Melbourne’99, and UrbanaIX three nucleon forces.

  12. Analysis and Determination of Plate Heat Exchanger's (PHE) Cooling Loadof Kartini Reactor Based on 250 kW Operation

    International Nuclear Information System (INIS)

    Suyamto; Maksum-Ischaq; Soeleman

    2000-01-01

    On behalf of increasing reactor power from 100 kW to 250 kW have beencarried out the analysis and determination of the Plate type Heat Exchanger's(PHE) cooling load. The analysis was carried out based on the present PHE'sperformances and the maximum water temperature allowed i.e T 11 = 41 o C.From the experiment where reactor operated at 100 kW for 6 hours or more atthe steady state condition was known that temperature of cooling water are :T 11 = 37 o C, T o1 = 33.71 o C, T 12 = 28.84 o C and T o2 = 29.64 o C,so that PHE's effectiveness is ε = 0.394. To analyse PHE's coolingload at 250 kW was estimated secondary input water temperature T 12 = 28.64 o C. The result shown that at reactor power level of 250 kW or 215x10 3 kcal/hr the flux mass of primary pump is 196.4 gpm which related to pumpingpower 13 Kw and the pipe diameter of 3 inch. While for secondary side : fluxmass is 254.4 gpm, pumping power 17.34 kW and the pipe diameter 4 inch. Inthis case also known that water temperature out from PHE are T o1 = 36.13 o C for primary and T o2 = 32.4 o C for secondary respectively. (author)

  13. 17 CFR 259.113 - Form U-13-1, for applications for approval of mutual service companies pursuant to Rule 88 (§ 250...

    Science.gov (United States)

    2010-04-01

    ... for approval of mutual service companies pursuant to Rule 88 (§ 250.88 of this chapter). 259.113....113 Form U-13-1, for applications for approval of mutual service companies pursuant to Rule 88 (§ 250... approval of a company as a mutual service company, by the company or person proposing to organize it under...

  14. Pharmacokinetics and tumor targeting of 131I-labeled F(ab')2 fragments of the chimeric monoclonal antibody G250: preclinical and clinical pilot studies.

    NARCIS (Netherlands)

    Brouwers, A.H.; Mulders, P.F.A.; Oosterwijk, E.; Buijs, W.C.A.M.; Corstens, F.H.M.; Boerman, O.C.; Oyen, W.J.G.

    2004-01-01

    INTRODUCTION: Clinical and animal studies of chimeric monoclonal antibody G250 (moAb cG250) for the targeting of clear-cell renal cell carcinoma (RCC), to date, have been with the intact IgG form. To determine whether F(ab')2 fragments are more suited for radioimmunotherapy (RIT) than intact IgG,

  15. 12 CFR 250.408 - Short-term negotiable notes of banks not securities under section 32, Banking Act of 1933.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Short-term negotiable notes of banks not securities under section 32, Banking Act of 1933. 250.408 Section 250.408 Banks and Banking FEDERAL RESERVE... securities under section 32, Banking Act of 1933. (a) The Board of Governors has been asked whether short...

  16. 12 CFR 250.220 - Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from...

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. 250.220 Section 250.220 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL...

  17. The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study

    DEFF Research Database (Denmark)

    Lindi, Virpi; Schwab, Ursula; Louheranta, Anne

    2007-01-01

    acids (SFA diet) or monounsaturated fatty acids (MUFA diet). Within groups there was a second random assignment to supplements with fish oil (3.6g n-3 FA/day) or placebo. At baseline, the A-250A genotype was associated with high serum LDL cholesterol concentration (P=0.030 among three genotypes......). On the MUFA diet carriers of the A-250A genotype presented a greater decrease in LDL cholesterol concentration than subjects with other genotypes (P=0.007 among three genotypes). The rare -250A allele was related to low HL activity (P... activity among the genotypes. CONCLUSION: The A-250A genotype of the LIPC gene was associated with high LDL cholesterol concentration, but the MUFA-enriched diet reduced serum LDL cholesterol concentration especially in subjects with the A-250A genotype. Udgivelsesdato: 2008-Feb...

  18. The Novel N-Substituted Benztropine Analog GA2-50 Possesses Pharmacokinetic and Pharmacodynamic Profiles Favorable for a Candidate Substitute Medication for Cocaine Abuse

    Science.gov (United States)

    OTHMAN, AHMED A.; NEWMAN, AMY H.; EDDINGTON, NATALIE D.

    2009-01-01

    GA2-50 is a novel N-substituted benztropine analog with improved potency and selectivity for the dopamine transporter. The pharmacokinetic and pharmacodynamic properties of GA2-50 were characterized as a part of its preclinical evaluation as a substitute medication for cocaine abuse. In vitro transport and metabolism studies as well as pharmacokinetic studies in rats were conducted. Effect of GA2-50 on the extracelluar nucleus accumbens (NAc) dopamine levels and on cocaine’s induced dopamine elevation was evaluated using intracerebral microdialysis. GA2-50 showed high transcellular permeability despite being a P-glycoprotein substrate. GA2-50 was a substrate of human CYP2D6, CYP2C19, CYP2E1, rat CYP2C11, CYP2D1, CYP3A1, and CYP1A2; with low intrinsic clearance values. In vivo, GA2-50 showed high brain uptake (Ri ~ 10), large volume of distribution (Vss =37 L/kg), and long elimination half-life (t½ =19 h). GA2-50 resulted in 1.6- and 2.7-fold dopamine elevation at the 5 and 10 mg/kg i.v. doses. Dopamine elevation induced by GA2-50 was significantly reduced, slower and longer lasting than previously observed for cocaine. GA2-50 had no significant effect on cocaine’s induced dopamine elevation upon simultaneous administration. Results from the present study indicate that GA2-50 possesses several attributes sought after for a substitute medication for cocaine abuse. PMID:18425847

  19. High reflectance Cr/C multilayer at 250 eV for soft X-ray polarimetry

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Mingwu; Jiang, Li; Zhang, Zhong; Huang, Qiushi [MOE Key Laboratory of Advanced Micro-Structured Materials, Institute of Precision Optical Engineering (IPOE), School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); Wang, Zhanshan, E-mail: wangzs@tongji.edu.cn [MOE Key Laboratory of Advanced Micro-Structured Materials, Institute of Precision Optical Engineering (IPOE), School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); She, Rui; Feng, Hua [Department of Engineering Physics, Tsinghua University, Beijing (China); Wang, Hongchang [Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE (United Kingdom)

    2015-10-01

    X-ray reflection near 45° via multilayer mirrors can be used for astronomical polarization measurements. A Cr/C multilayer mirror (designed for X-ray polarimetry at 250 eV), with a period thickness of 3.86 nm and a bi-layer number of 100, was fabricated using direct current magnetron sputtering. Grazing incidence X-ray reflectometry at 8 keV and transmission electron microscopy were used to investigate the multilayer structure. Different models were introduced to fit the hard X-ray reflectivity curve, which indicates that the layer thickness of two materials slightly drifts from the bottom to the top of the stack. Both the chromium and carbon layers are amorphous with asymmetric interfaces, while the Cr-on-C interface is slightly wider. Based on the good quality of the multilayer structure, a high reflectivity of 21.8% for the s-polarized light was obtained at 250 eV at a grazing incidence angle of 40.7°. The fabricated Cr/C multilayer mirror exhibits high reflectivity and polarization levels in the energy region of 240 eV–260 eV. - Highlights: • We fabricated Cr/C multilayer with 3.8 nm d-spacing. • X-ray reflectometry was used to determine the exact structure of Cr/C multilayer. • A high reflectivity of 21.8% for the s-polarized light was obtained at 250 eV. • Both Cr and C were found to be amorphous with slightly asymmetric interfaces. • A 4-layer model was used to fit and explain the results.

  20. A dense grid of narrow bandpass steep edge filters for the JST/T250 telescope: summary of results

    Science.gov (United States)

    Brauneck, U.; Sprengard, R.; Bourquin, S.; Marín-Franch, A.

    2017-09-01

    On the Javalambre mountain in Spain, the Centro de Estudios de Fisica del Cosmos de Aragon (CEFCA) has setup a new wide field telescope, the JST/T250: a 2.55 m telescope with a plate scale of 22.67"/mm and a 3° diameter field of view. To conduct a photometric sky survey, a large format mosaic camera made of 14 individual CCDs is used in combination with filter trays containing 14 filters each of theses 101.7 x 96.5 mm in size. For this instrument, SCHOTT manufactured 56 specially designed steep edged bandpass interference filters which were recently completed. The filter set consists of bandpass filters in the range between 348,5 nm and 910 nm and a longpass filter at 915 nm. Most of the filters have FWHM of 14.5 nm and a blocking between 250 and 1050 nm with optical density of OD5. Absorptive color glass substrates in combination with interference filters were used to minimize residual reflection in order to avoid ghost images. Inspite of containing absorptive elements, the filters show the maximum possible transmission. This was achieved by using magnetron sputtering for the filter coating process. The most important requirement for the continuous photometric survey is the tight tolerancing of the central wavelengths and FWHM of the filters. This insures each bandpass having a defined overlap with its neighbors. In addition, the blocking of the filters is better than OD5 in the range 250-1050 nm. A high image quality required a low transmitted wavefront error (

  1. Analysis of MODIS 250 m Time Series Product for LULC Classification and Retrieval of Crop Biophysical Parameter

    Science.gov (United States)

    Verma, A. K.; Garg, P. K.; Prasad, K. S. H.; Dadhwal, V. K.

    2016-12-01

    Agriculture is a backbone of Indian economy, providing livelihood to about 70% of the population. The primary objective of this research is to investigate the general applicability of time-series MODIS 250m Normalized difference vegetation index (NDVI) and Enhanced vegetation index (EVI) data for various Land use/Land cover (LULC) classification. The other objective is the retrieval of crop biophysical parameter using MODIS 250m resolution data. The Uttar Pradesh state of India is selected for this research work. A field study of 38 farms was conducted during entire crop season of the year 2015 to evaluate the applicability of MODIS 8-day, 250m resolution composite images for assessment of crop condition. The spectroradiometer is used for ground reflectance and the AccuPAR LP-80 Ceptometer is used to measure the agricultural crops Leaf Area Index (LAI). The AccuPAR measures Photosynthetically Active Radiation (PAR) and can invert these readings to give LAI for plant canopy. Ground-based canopy reflectance and LAI were used to calibrate a radiative transfer model to create look-up table (LUT) that was used to simulate LAI. The seasonal trend of MODIS-derived LAI was used to find crop parameter by adjusting the LAI simulated from climate-based crop yield model. Cloud free MODIS images of 250m resolution (16 day composite period) were downloaded using LP-DAAC website over a period of 12 months (Jan to Dec 2015). MODIS both the VI products were found to have sufficient spectral, spatial and temporal resolution to detect unique signatures for each class (water, fallow land, urban, dense vegetation, orchard, sugarcane and other crops). Ground truth data were collected using JUNO GPS. Multi-temporal VI signatures for vegetation classes were consistent with its general phenological characteristic and were spectrally separable at some point during the growing season. The MODIS NDVI and EVI multi-temporal images tracked similar seasonal responses for all croplands and were

  2. Research and practice of the reformation of the mass-spectrometer MAT-250 UF's auto-measure system improvement

    International Nuclear Information System (INIS)

    Hao Xueyuan; Kang Jianyou; Xie Zhuangying

    1999-03-01

    By analyzing and studying the hardware and software of the mass-spectrometer MAT-250UF's original automatic measuring system, the original system is replaced with a new system consisting of the IEEE-488 interface, a modern PC serial microcomputer and the analyzing software programmed by the author. The original system repairing and direct replacing difficulties are resolved. The new system is adaptable to the practical application in routine analytical job and study, and to modern analysis standard verified by standard sample, the new system operates perfectly

  3. Energy investments needs are estimated to $250 milliards, 1995-2010, in the South and East Mediterranean countries

    International Nuclear Information System (INIS)

    Calvet, B.

    1996-01-01

    The energy consumption knows a sharper increase in the North and in the East of the Mediterranean sea than in European Union. These trends should continue during the two next decades. From now until 2010, according to the companies predictions, the energy consumption of the free trade future zone countries should continue to strongly increase, to reach near 2 000 millions of petroleum equivalent tons. Then, the financing needs should reach some $250 milliards according to an inquiry of the Energy Mediterranean Observatory. (N.C.)

  4. [Clinical development of acute noise-induced acoustic trauma. An evaluation of a study of 250 cases].

    Science.gov (United States)

    Suc, B; Poulet, M; Asperge, A; Vix, J; Barberot, J P; Doucet, F

    1994-01-01

    Traumatic damage on Cochlea (250 cases) induced by assault gun (F.A.M.A.S.) consists in tinitus and hearing impairement on 6000 Hz. Noise's effects are specific to one Cochlea. Dissociated developments of both tinitus and hearing loss show that their anatomical sites are different. Acoustic injury entails definitive haire cells lesions, cellular biochemical and vascular changes. The treatment that reestablishes or raises cochlear blood flow entails recovery in 80% of cases provided that it is given within 48 hours after the trauma.

  5. Possibility of construction in Bulgaria of a fast neutron therapy center on the base of the U-250 isochronous cyclotron

    International Nuclear Information System (INIS)

    Angelov, V.A.; Enchevich, I.B.

    1985-01-01

    Development of oncological disease treatment by fast neutrons in the world practice is reviewed. Main radiobiological results, which point to peculiarities of neutron therapy in comparison with standard X-ray therapy are considered. Main requirements for devices to be met, used in fast neutron therapy, are enumerated. On the basis of it, the possibility of construction in Bulgaria a fast neutron therapy center using the U-250 multipurpose cyclotron has been made. The conclusion is made that the main parameters of a proton beam in combination with an isocentrical head as a fast neutron source will create the conditions for realization of high-efficiency neutron therapy

  6. A Cryostat for Automated mK-Level Thermometer Calibrations from -202 °C to 250 °C

    Science.gov (United States)

    Ballico, Mark; Freund, Chris

    2011-12-01

    The National Measurement Institute of Australia (NMIA) has developed a vacuum cryostat capable of calibrating precision electronic thermometers with a transfer error less than 2 mK over the range from -202 °C to 250 °C. The calibration of precision temperature measurement probes such as platinum resistance thermometers is usually performed in circulated fluid baths to achieve mK-level calibration uncertainties, and requires the use of several baths to cover the commonly used range of -80 °C to 250°C. Below -80 °C, dry-well systems cooled by liquid nitrogen are available down to -196 °C, but achieve poor uniformity and stability. The increased use of cryogenic preservation in the biomedical area has seen an increase in demand for precision calibration of electronic thermometer systems, in particular, down to a few degrees below the boiling point of nitrogen (-196 °C). This has prompted NMIA to develop a new design of a dry-well calibrator, based around a 380 mm long, 50 mm diameter, oxygen-free copper block insulated by gold-plated radiation and guard shields. Temperatures down to -202 °C are achieved by controlling the flow of liquid nitrogen through a restricting orifice into an evacuated heat exchanger. Computer control of the nitrogen flow and of several immersion heaters achieve a temperature stability of a few mK at all temperatures over the operational range, requiring typically 60 min to equilibrate at each new setpoint. Radiative transfer limits operation to 250 °C where the uniformity is 0.5 mK · cm-1 (and becoming negligible at lower temperatures). A significant design innovation is the thermometer entry region, which has a purge system to keep the wells free of condensed moisture or atmospheric gases without the need for a seal. As the block is only 50 mm from the face of the cryostat, thermometers as short as 250 mm can be calibrated. The system is now in regular use at NMIA providing fully automated calibrations of precison temperature

  7. Triggered degradation of 250 μm-thick Mg targets using acetic acid for transient electronic applications

    Directory of Open Access Journals (Sweden)

    Zhiyuan Zhu

    2017-07-01

    Full Text Available Transient electronics are becoming a hot topic due to the rapid development of bioelectronics, self-destructive devices and environmental sensors. This letter reports a novel scheme for triggering degradation of 250 μm-thick Mg target using acetic acid regarding transient electronics applications. The triggered transience has also been demonstrated using commercial vinegar. To achieve programmable transience as well as device protection, polypropylene carbonate (PPC was investigated as passivation layer. The proposed method has demonstrated simplicity, high safety, low cost and low trigger temperature.

  8. Development of an alternative low-cost solar collector working at medium temperature (150 - 250°C)

    Science.gov (United States)

    Vidal, Frédéric; Chandez, Bertrand; Albert, Raphael

    2017-06-01

    Within the subtask 11.1.1 of the European project STAGE-STE, the CEA is in charge of the development of an alternative low-cost collector working at medium temperature (150-250 °C). PTC are installed in a small glasshouse in order to decrease the steel mass of the solar field. After a brief background of alternative PTC construction, characteristics and advantages of such a collector are presented and PTC arrangement performance (axis orientation, tilt angle) are discussed. Then, some mechanical studies are detailed and three prototypes module design are presented as well as their optical qualification.

  9. MODIS 250M burnt area detection algorithm: A case study applied, optimized and evaluated over continental Portugal.

    Science.gov (United States)

    Mota, Bernardo; Benali, Akli; Pereira, Jose Miguel

    2014-05-01

    The dependence on satellites to derive burnt area (BA) maps is unquestionable. High resolution inventories normally result from change detection algorithms applied to pre and post fire season high resolution imagery. But these have no temporal discrimination within the occurring season. Limited to the larger fire scars, coarser resolution imagery based on reflectance or thermal information can help to map the individual fire progression. The Moderate Resolution Imaging Spectroradiometer (MODIS) 250m imagery bands, freely available, can be used to provide quick areal estimates and provide the needed temporal discrimination with four times the standard spatial resolution BA products. The scope of this study is to assess the spatial and temporal accuracy of burnt area maps derived by the MODIS 250m resolution Burnt Area algorithm (M250BA) presented by Mota et al., (2013) on an Mediterranean landscape. The algorithm is an improved adaptation of one of the burnt area algorithms developed within the scope of the Fire_CCI project and was applied to an area covering continental Portugal for the period of 2001-2013. The algorithm comprises a temporal analysis based on change point detections and a spatial analysis based on Markov random fields. We explored the benefits of applying standard optimization techniques to the algorithm and achieved significant performance improvements.. Temporal and spatial accuracy assessments were performed by comparing the results with spatial and temporal distribution of active fire maps and with high resolution burnt area maps, derived by the MCD14ML thermal anomalies dataset and by Landsat BA classifications, respectively. Accuracy results highlight the potential applications for this BA algorithm and the advantages of using 250m spatial resolution images for BA detection. The study also extends the current national burnt area atlas since 2010. Due to the open-access data policy, the algorithm can be easily parameterised and applied to any

  10. Observation of classical rotational inertia and nonclassical supersolid signals in solid 4He below 250 mK.

    Science.gov (United States)

    Rittner, Ann Sophie C; Reppy, John D

    2006-10-20

    We have confirmed the existence, as first reported by Kim and Chan, of a supersolid state in solid 4He at temperatures below 250 mK. We have employed a torsional oscillator cell with a square cross section to insure a locking of the solid to the oscillating cell. We find that the nonclassical rotational inertia signal is not a universal property of solid 4He but can be eliminated through an annealing of the solid helium sample. This result has important implications for our understanding of the supersolid state.

  11. Downscaling 250-m MODIS growing season NDVI based on multiple-date landsat images and data mining approaches

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.

    2015-01-01

    The satellite-derived growing season time-integrated Normalized Difference Vegetation Index (GSN) has been used as a proxy for vegetation biomass productivity. The 250-m GSN data estimated from the Moderate Resolution Imaging Spectroradiometer (MODIS) sensors have been used for terrestrial ecosystem modeling and monitoring. High temporal resolution with a wide range of wavelengths make the MODIS land surface products robust and reliable. The long-term 30-m Landsat data provide spatial detailed information for characterizing human-scale processes and have been used for land cover and land change studies. The main goal of this study is to combine 250-m MODIS GSN and 30-m Landsat observations to generate a quality-improved high spatial resolution (30-m) GSN database. A rule-based piecewise regression GSN model based on MODIS and Landsat data was developed. Results show a strong correlation between predicted GSN and actual GSN (r = 0.97, average error = 0.026). The most important Landsat variables in the GSN model are Normalized Difference Vegetation Indices (NDVIs) in May and August. The derived MODIS-Landsat-based 30-m GSN map provides biophysical information for moderate-scale ecological features. This multiple sensor study retains the detailed seasonal dynamic information captured by MODIS and leverages the high-resolution information from Landsat, which will be useful for regional ecosystem studies.

  12. Immunoscintigraphy of septic loosening of knee endoprosthesis: a retrospective evaluation of the antigranulocyte antibody BW 250/183

    Energy Technology Data Exchange (ETDEWEB)

    Klett, Rigobert; Khalisi, Alexander; Puille, Maximillian; Steiner, Dagmar; Bauer, Richard [Clinic of Nuclear Medicine, University Hospital Giessen, Friedrichstrasse 25, 35385, Giessen (Germany); Kordelle, Jens [Orthopedic Clinic, University Hospital Giessen (Germany); Stahl, Ulrich [Department of Pathology, University Hospital Giessen (Germany)

    2003-11-01

    Immunoscintigraphy with the use of the antigranulocyte antibody BW 250/183 is a reliable method for detecting infection, especially in septic loosening of hip prostheses, for which purpose quantitative interpretation of the time-activity course is employed. Therefore, we retrospectively studied whether similar results could be achieved in knee prostheses. We verified 28 scintigraphic examinations in 26 patients by histology. Scintigraphy was performed during an early (4-6 h post injection) and a late phase (23-25 h post injection). Infection was diagnosed when activity around the knee prosthesis increased by more than 10% compared with bone marrow. We found a sensitivity and a negative predictive value of 100%, a specificity of 80%, a positive predictive value of 81% and an accuracy of 89%. Specificity and accuracy are lower than in the evaluation of hip prostheses; however, in comparison to other scintigraphic modalities, scintigraphy with the antigranulocyte antibody BW 250/183 is superior in excluding infection and has better specificity and accuracy. Therefore, as in the case of hip prostheses, the described methodology appears to be the scintigraphic modality of choice for knee prostheses. (orig.)

  13. Origin of TSL peaks located at 200-250 K in UV-irradiated PbWO4 crystals

    International Nuclear Information System (INIS)

    Fabeni, P.; Krasnikov, A.; Laguta, V.V.; Nikl, M.; Pazzi, G.P.; Susini, C.; Zazubovich, S.

    2007-01-01

    Thermally stimulated luminescence (TSL) was studied for many PbWO 4 crystals after their selective irradiation at 80-220 K in the 3.4-5.0 eV energy range to clarify the origin of the defects responsible for the TSL peaks located in the 200-250 K range. The conclusion is made that both in PbWO 4 and PbWO 4 :Mo crystals the total TSL intensity and the intensity ratio of various TSL peaks are mainly determined by the concentration and type of oxygen and lead vacancies which depend on the crystal preparation and annealing conditions and on the concentration of trivalent rare-earth impurity ions. The TSL peak near 200 K is ascribed to {Pb + -WO 3 } centers and the peak in the 210-230 K range, to the electron centers, containing oxygen vacancies of the type of WO 2 and WO. Only the 250 K peak arises from electron MoO 4 3- centers. Thermally stimulated processes are accompanied with the green G(II) emission

  14. HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A

    International Nuclear Information System (INIS)

    Van Rechem, Capucine; Boulay, Gaylor; Leprince, Dominique

    2009-01-01

    HIC1, a tumor suppressor gene epigenetically silenced in many human cancers encodes a transcriptional repressor involved in regulatory loops modulating p53-dependent and E2F1-dependent cell survival and stress responses. HIC1 is also implicated in growth control since it recruits BRG1, one of the two alternative ATPases (BRM or BRG1) of SWI/SNF chromatin-remodeling complexes to repress transcription of E2F1 in quiescent fibroblasts. Here, through yeast two-hybrid screening, we identify ARID1A/BAF250A, as a new HIC1 partner. ARID1A/BAF250A is one of the two mutually exclusive ARID1-containing subunits of SWI/SNF complexes which define subsets of complexes endowed with anti-proliferative properties. Co-immunoprecipitation assays in WI38 fibroblasts and in BRG1-/- SW13 cells showed that endogenous HIC1 and ARID1A proteins interact in a BRG1-dependent manner. Furthermore, we demonstrate that HIC1 does not interact with BRM. Finally, sequential chromatin immunoprecipitation (ChIP-reChIP) experiments demonstrated that HIC1 represses E2F1 through the recruitment of anti-proliferative SWI/SNF complexes containing ARID1A.

  15. Detection of lung and bone infection with anti-granulocyte monoclonal antibody BW 250/183 radiolabelled with 99Tcm.

    Science.gov (United States)

    Peltier, P; Potel, G; Lovat, E; Baron, D; Chatal, J F

    1993-09-01

    Twenty-four patients with suspected infection (eight bone, 16 lung) were studied using monoclonal antibody BW250/183 which recognizes epitopes present on the surface of granulocytes. Bronchofibroscopic samples (microbiological studies and alveolar cell counts) were obtained from 14/16 patients with lung disease. Bronchofibroscopy isolated a micro-organism nine times. In two other cases, the diagnosis of infection was based on clinical course data. Infection was confirmed by surgical biopsy in the eight patients with bone pathology. Scans were performed 2 and 24 h after injection of 1 mg BW 250/183 labelled with 99Tcm. For lung disease, immunoscintigraphy was positive six times (five true positive, one false positive) and negative 10 times (six false negative, four true negative). Immunoscintigraphy was false negative when the lung infection was not systematized or no granulocytes were mobilized in the infectious site. Immunoscintigraphy was falsely positive when noninfectious lung disease mobilized granulocytes. It was positive in all patients with bone infection. Images recorded at 24 h had better sensitivity (five false negative) than those at 2 h (eight false negative).

  16. Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis.

    Science.gov (United States)

    Zhu, Ping; Li, Xiao-Yan; Wang, Hong-Kun; Jia, Jun-Feng; Zheng, Zhao-Hui; Ding, Jin; Fan, Chun-Mei

    2007-01-01

    Oral antigen is an attractive approach for the treatment of autoimmune and inflammatory diseases. Establishment of immune markers and methods in evaluating the effects of antigen-specific cellular and humoral immune responses will help the application of oral tolerance in the treatment of human diseases. The present article observed the effects of chicken collagen II (CII), the recombinant polymerized human collagen II 250-270 (rhCII 250-270) peptide and synthesized human CII 250-270 (syCII 250-270) peptide on the induction of antigen-specific autoimmune response in rheumatoid arthritis (RA) peripheral blood mononuclear cells (PBMC) and on the specific cellular and humoral immune response in collagen-induced arthritis (CIA) and mice fed with CII (250-270) prior to immunization with CII. In the study, proliferation, activation and intracellular cytokine production of antigen-specific T lymphocytes were simultaneously analyzed by bromodeoxyuridine (BrdU) incorporation and flow cytometry at the single-cell level. The antigen-specific antibody and antibody-forming cells were detected by ELISA and ELISPOT, respectively. CII (250-270) was found to have stimulated the response of specific lymphocytes in PBMC from RA patients, including the increase expression of surface activation antigen marker CD69 and CD25, and DNA synthesis. Mice, fed with CII (250-270) before CII immunization, had significantly lower arthritic scores than the mice immunized with CII alone, and the body weight of the former increased during the study period. Furthermore, the specific T cell activity, proliferation and secretion of interferon (IFN)-gamma in spleen cells were actively suppressed in CII (250-270)-fed mice, and the serum anti-CII, anti-CII (250-270) antibody activities and the frequency of specific antibody-forming spleen cells were significantly lower in CII (250-270)-fed mice than in mice immunized with CII alone. These observations suggest that oral administration of CII (250-270) can

  17. The Clinicopathologic Significance of p53 and BAF-250a (ARID1A) Expression in Clear Cell Carcinoma of the Endometrium

    OpenAIRE

    Fadare, Oluwole; Gwin, Katja; Desouki, Mohamed M.; Crispens, Marta A.; Jones, Howard W.; Khabele, Dineo; Liang, Sharon X.; Zheng, Wenxin; Mohammed, Khaled; Hecht, Jonathan L.; Parkash, Vinita

    2013-01-01

    TP53 mutation (and associated p53 protein overexpression) is probably a negative prognostic marker in endometrial cancers, but its relevance in the rarer histologic subtypes, including clear cell carcinomas, has not been delineated. Preclinical studies suggest functional interactions between p53 and the BAF250a protein, the product of a tumor suppressor gene ARID1A that is frequently mutated in ovarian clear cell carcinoma. In this study, we evaluated the significance of p53 and BAF250a expre...

  18. ERP C250 shows the elderly (cognitively normal, Alzheimer's disease) store more stimuli in short-term memory than Young Adults do.

    Science.gov (United States)

    Chapman, Robert M; Gardner, Margaret N; Mapstone, Mark; Klorman, Rafael; Porsteinsson, Anton P; Dupree, Haley M; Antonsdottir, Inga M; Kamalyan, Lily

    2016-06-01

    To determine how aging and dementia affect the brain's initial storing of task-relevant and irrelevant information in short-term memory. We used brain Event-Related Potentials (ERPs) to measure short-term memory storage (ERP component C250) in 36 Young Adults, 36 Normal Elderly, and 36 early-stage AD subjects. Participants performed the Number-Letter task, a cognitive paradigm requiring memory storage of a first relevant stimulus to compare it with a second stimulus. In Young Adults, C250 was more positive for the first task-relevant stimulus compared to all other stimuli. C250 in Normal Elderly and AD subjects was roughly the same to relevant and irrelevant stimuli in Intratrial Parts 1-3 but not 4. The AD group had lower C250 to relevant stimuli in part 1. Both normal aging and dementia cause less differentiation of relevant from irrelevant information in initial storage. There was a large aging effect involving differences in the pattern of C250 responses of the Young Adult versus the Normal Elderly/AD groups. Also, a potential dementia effect was obtained. C250 is a candidate tool for measuring short-term memory performance on a biological level, as well as a potential marker for memory changes due to normal aging and dementia. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  19. 250-kW-fuel cell system. Fields of application and operational experience (carbonate fuel cell technology); 250-kW-Brennstoffzellenanlage. Einsatzbereiche und Betriebserfahrungen (Karbonat-Brennstoffzellen Technologie)

    Energy Technology Data Exchange (ETDEWEB)

    Berger, P. [MTU CFC Solutions GmbH, Muenchen (Germany)

    2005-07-01

    The author shows us a 250 kW-carbonate fuel cell system, describing the technical properties of the system based on the carbonate fuel cell technology. The system operates with relatively high cell temperatures, can be operated using methan as a fuel and it can generate process vapour in addition to electric power. The article shows the fields of application, giving also a concrete example and illustrating the mode of operation of the fuel cell system which is advantageous, from the environment-related point of view. 1. Technical properties fuel cell power plant 2. Advantages in decentralized energy techniques 3. Applications, markets and objective groups 4. A case example for the ITK branch: Deutsche Telekom 5. Renewable and CO2-neutral energy supply.

  20. Large self-affine fractality in $\\pi^{+}p$ and $K^{+}p$ collisions at 250 GeV/c

    CERN Document Server

    Agababian, N M

    1996-01-01

    Taking into account the anisotropy of phase space in multiparticle production, a self-affine analysis of factorial moments was carried out on the NA22 data for $\\pi^{+}p$ and $K^{+}p$ collisions at 250 GeV/$c$. Within the transverse plane, the Hurst exponents measuring the anisotropy are consistent with unit value (i.e. no anisotropy). They are, however, only half that value when the longitudinal direction is compared to the transverse ones. Fractality, indeed, turns out to be self-affine rather than self-similar in multiparticle production. In three-dimensional phase space, power-law scaling is observed to be better realized in self-affine than in self-similar analysis.

  1. A reflectivity profilometer for the optical characterisation of graded reflectivity mirrors in the 250 nm - 1100 nm spectral region

    International Nuclear Information System (INIS)

    Colucci, Alessandro; Nichelatti, Enrico

    1998-04-01

    It's developed the prototype of an instrument that can be used for the optical characterisation of graded reflectivity mirrors at any wavelength in the spectral region from 250 nm to 1100 nm. The instrument utilises a high-pressure Xe arc lamp as light source. Light is spectrally filtered by means of a grating monochromator. The sample is illuminated with an image of the monochromator exit slit. After reflection from the sample, this image is projected onto a 1024-elements charge-coupled device linear array driven by a digital frame board and interfaced with a personal computer. It's tested the instrument accuracy by comparing measurement results with the corresponding ones obtained by means of a laser scanning technique. Measurement Rms repeatability has been estimated to be approximately of 0.8% [it

  2. Early phyllosilicates formed by alteration of R7T7 glass in water at 250 deg C

    International Nuclear Information System (INIS)

    Vernaz, E.; Dussossoy, J.L.; Caurel, J.; Crovisier, J.L.

    1991-01-01

    T7T7 glass samples have been altered during periods of one and seven days at 250 deg C in distilled water. Ultramicrotomic thin sections were performed in the outermost part of the glass for a study under analytical transmission electron microscope. After one day the alteration layer is about 5 μm thick. It is made up of sheeted silicated particles, tentatively identified as septechlorite (7 A intervals) mixed with an intercrystalline amorphous matrix of different composition. After seven days the alteration layer is about 11 μm thick. It is made up of sheeted silicated particles of smectite type (10 A intervals). No 7 A particles were found in the seven days sample. This study illustrates the capacity of poorly crystalline phyllosilicates to adapt to the chemical changes in solution. 15 refs., 4 tabs., 2 plates

  3. Molecular hydrogen in the z = 2.811 absorbing material toward the quasar PKS 0528-250

    International Nuclear Information System (INIS)

    Levshakov, S.A.; Varshalovich, D.A.

    1985-01-01

    Among the previously unidentified absorbtion features in the spectrum of the quasar PKS 0528-250 obtained by previous authors tentative evidence has been found for H 2 lines at the same redshift (z = 2.811) as that of the well-known absorption-line system. The column density of molecules has been estimated from the curve of growth; the fraction of H 2 appears to be about 2 x 10 -5 . The ortho- to para-H 2 ratio corresponds to the excitation temperature of Tsub(ex)(H 2 ) = 300 +- 150 K, though the upper rotational levels J >= 3 turn out be overpopulated. The results obtained seem to provide substantial evidence for the existence of molecular hydrogen at the early cosmological epoch with z approx. 3. (author)

  4. About 250 cases of skeletal scintiscanning using sup(99m)Tc-labelled stannous pyrophosphate. Analytical and critical study

    International Nuclear Information System (INIS)

    Suss, Leopold.

    1975-01-01

    The physical and biological characteristics of 85 Sr, 87 Sr, 18 F and sup(99m)Tc, four radionuclides suitable for skeletal imaging are reviewed. Their mechanism of localization, advantages and disadvantages are described. The physical characteristics and relative tissue concentration of sup(99m)Tc compare favorably to those of the other bone-seeking radionuclides. 250 cases of various skeletal diseases are presented, using sup(99m)Tc-pyrophosphate as a skeletal imaging agent. This radiopharmaceutical proves to be useful particularly in the detection of bone metastases. Bone scans, however, are not 100% positive with metastatic diseases and false negative do occasionally occur. The scan is also helpful in demonstrating the extent of metastatic bone disease [fr

  5. Measurements of the n->d scattering at 250 MeV and three-nucleon forces

    International Nuclear Information System (INIS)

    Maeda, Y.; Sakai, H.; Fujita, K.; Hatano, M.; Kamiya, J.; Kawabata, T.; Kuboki, H.; Hatanaka, K.; Okamura, H.; Saito, T.; Sakemi, Y.; Sasano, M.; Sekiguchi, K.; Shimizu, Y.; Suda, K.; Tameshige, Y.; Tamii, A.; Wakasa, T.; Yako, K.; Greenfield, M.B.; Kamada, H.; Witala, H.

    2007-01-01

    The differential cross sections and the vector analyzing powers for the nd elastic scattering at E n = 250 MeV have been measured for the study of the three-nucleon force (3NF) effects in the Coulomb-free system. To cover a wide angular region, the experiments were performed by using two different methods at the (n, p) facility and at the NTOF facility which constructed at the Research Center for Nuclear Physics (RCNP). The results were compared with theoretical predictions of the Faddeev calculations based on the modern nucleon-nucleon (NN) forces with the three-nucleon force (3NF). The inclusion of 3NFs leads to a good description of the cross section except for the backward angles. The results were also compared with the theoretical predictions with relativistic corrections. The direct data-to-data comparison of the cross sections of the nd and pd was performed

  6. Construction and start-up of a 250 kW natural gas fueled MCFC demonstration power plant

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa, R.A.; Carter, J.; Rivera, R.; Otahal, J. [San Diego Gas & Electric, CA (United States)] [and others

    1996-12-31

    San Diego Gas & Electric (SDG&E) is participating with M-C Power in the development and commercialization program of their internally manifolded heat exchanger (IMHEX{reg_sign}) carbonate fuel cell technology. Development of the IMHEX technology base on the UNOCAL test facility resulted in the demonstration of a 250 kW thermally integrated power plant located at the Naval Air Station at Miramar, California. The members of the commercialization team lead by M-C Power (MCP) include Bechtel Corporation, Stewart & Stevenson Services, Inc., and Ishikawajima-Harima Heavy Industries (IHI). MCP produced the fuel cell stack, Bechtel was responsible for the process engineering including the control system, Stewart & Stevenson was responsible for packaging the process equipment in a skid (pumps, desulfurizer, gas heater, turbo, heat exchanger and stem generator), IHI produced a compact flat plate catalytic reformer operating on natural gas, and SDG&E assumed responsibility for plant construction, start-up and operation of the plant.

  7. Water density and polarizability deduced from the refractive index determined by interferometric measurements up to 250 MPa.

    Science.gov (United States)

    Weiss, L; Tazibt, A; Tidu, A; Aillerie, M

    2012-03-28

    The refractive index of water is precisely determined in the visible light range as a function of the pressure until 250 MPa by means of a new measurement device that uses a special pipe tee included in an interferometer set. This technique allows revisiting the Bradley-Tait and Sellmeier equations to make them dependent on the wavelength and the pressure, respectively. The Bradley-Tait equation for the pressure dependence of the water refractive index is completed by a wavelength-dependent factor. Also, in the considered pressure and wavelength ranges, it is shown that the Sellmeier coefficients can be straightforwardly linked to the pressure, allowing the determination of the refractive index of water for either any wavelength or pressure. A new simple model allows the determination of the density of water as a function of the measured refractive index. Finally, the polarizability of water as function of pressure and wavelength is calculated by means of the Lorentz-Lorenz equation.

  8. Personal dose equivalent conversion coefficients for neutron fluence over the energy range of 20-250 MeV.

    Science.gov (United States)

    Olsher, R H; McLean, T D; Justus, A L; Devine, R T; Gadd, M S

    2010-03-01

    Monte Carlo simulations were performed to extend existing neutron personal dose equivalent fluence-to-dose conversion coefficients to an energy of 250 MeV. Presently, conversion coefficients, H(p,slab)(10,alpha)/Phi, are given by ICRP-74 and ICRU-57 for a range of angles of radiation incidence (alpha = 0, 15, 30, 45, 60 and 75 degrees ) in the energy range from thermal to 20 MeV. Standard practice has been to base operational dose quantity calculations 20 MeV. Both light and heavy ions (HIs) (carbon, nitrogen and oxygen recoil nuclei) were transported down to a lower energy limit (1 keV for light ions and 5 MeV for HIs). Track energy below the limit was assumed to be locally deposited. For neutron tracks slab phantom.

  9. Photodegradation of 17α-ethynylestradiol in aqueous solution exposed to a high-pressure mercury lamp (250 W)

    International Nuclear Information System (INIS)

    Liu, X.L.; Wu, F.; Deng, N.S.

    2003-01-01

    The photodegradation of 17α-ethynylestradiol (EE 2 ) induced by high-pressure mercury lamp (λ≥313, 250 W) in aqueous solution of EE 2 was investigated initially. The affecting factors on the photodegradation were studied and described in details, such as EE 2 initial concentration, Fe 3+ , algae, exposure time, and so on. The concentration of EE 2 in distilled water was mainly determined using fluorescence spectrophotometer. The photodegradation of EE 2 in aqueous solution exposed to high-pressure mercury lamp was evident and could be accelerated by Fe 3+ or algae (e.g. Anabaena cylindrica) in general. With the algae concentration increasing, photodegradation rate increased. In this paper, the mechanism of photocatalytic degradation of EE 2 by Fe 3+ or algae is discussed primarily. - Photodegradation increased with increasing concentrations of algae

  10. Radiation from an equilibrium CO2-N2 plasma in the [250-850 nm] spectral region: II. Spectral modelling

    International Nuclear Information System (INIS)

    Silva, M Lino da; Vacher, D; Andre, P; Faure, G; Dudeck, M

    2008-01-01

    In the first part of this work, described in a previous paper, the thermodynamic conditions in an atmospheric pressure inductively coupled CO 2 -N 2 plasma have been determined, and the radiation emission spectrum has been measured and calibrated in the [250-850 nm] spectral region. In the second part of this work, a synthetic radiation spectrum is obtained taking into account (a) the geometry of the plasma torch and (b) the local thermodynamic conditions of the plasma. This synthetic spectrum has then been compared against the measured spectrum. The good agreement between the two spectra allows validating the spectral database of the line-by-line code SPARTAN for the simulation of the radiative emission of CO 2 -N 2 plasmas from the near-UV to the near-IR spectral region.

  11. Thermal analysis of a conceptual design for a 250 W(e) GPHS/FPSE space power system

    International Nuclear Information System (INIS)

    Mccomas, T.J.; Dugan, E.T.

    1991-01-01

    A thermal analysis has been performed for a 250-W(e) space nuclear power system which combines the US Department of Energy's general purpose heat source (GPHS) modules with a state-of-the-art free-piston Stirling engine (FPSE). The focus of the analysis is on the temperature of the indium fuel clad within the GPHS modules. The thermal analysis results indicate fuel clad temperatures slightly higher than the design goal temperature of 1573 K. The results are considered favorable due to numerous conservative assumptions used. To demonstrate the effects of the conservatism, a brief sensitivity analysis is performed in which a few of the key system parameters are varied to determine their effect on the fuel clad temperatures. It is shown that thermal analysis of a more detailed thermal mode should yield fuel clad temperatures below 1573 K. 3 refs

  12. A reflectivity profilometer for the optical characterisation of grade reflectivity mirrors in the 250 nm - 1100 nm spectral region

    Energy Technology Data Exchange (ETDEWEB)

    Colucci, Alessandro; Nichelatti, Enrico [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Innovazione

    1998-04-01

    It`s developed the prototype of an instrument that can be used for the optical characterisation of graded reflectivity mirrors at any wavelength in the spectral region from 250 nm to 1100 nm. The instrument utilises a high-pressure Xe arc lamp as light source. Light is spectrally filtered by means of a grating monochromator. The sample is illuminated with an image of the monochromator exit slit. After reflection from the sample, this image is projected onto a 1024-elements charge-coupled device linear array driven by a digital frame board and interfaced with a personal computer. It`s tested the instrument accuracy by comparing measurement results with the corresponding ones obtained by means of a laser scanning technique. Measurement Rms repeatability has been estimated to be approximately of 0.8%. [Italiano] E` stato sviluppato il prototipo di uno strumento per la catatterizzazione ottica di specchi a riflettivita` variabile, operante a qualsiasi lunghezza d`onda nell`intervallo spettrale da 250 nm a 1100 nm. La sorgente dello strumento e` una lampada ad arco allo Xenon ad alta pressione. La luce e` filtrata spettralmente per mezzo di un monocromatore a reticolo. Il campione viene illuminato da un`immagine della fenditura d`uscita del monocromatore. Dopo essere stata riflessa dal campione, questa immagine viene proiettata su un array CCD lineare a 1024 elementi, connesso elettronicamente a una scheda digitale e interfacciato a un personal computer. L`accuratezza dello strumento e` stata verificata confrontando alcune misure con le corrispondenti misure ottenute mediante una tecnica a scansione laser. La ripetibilita` RMS delle misure e` stata stimata essere circa dello 0.8%.

  13. Desarrollo de la formulación de cefalexina 250 mg granulado para suspensión oral

    Directory of Open Access Journals (Sweden)

    Roxana Martínez Fernández

    2002-04-01

    Full Text Available Se desarrolló la formulación de la cefalexina 250 mg como granulado para suspensión oral. Se utilizó la vía húmeda para la preparación del granulado, teniendo en cuenta los resultados de la caracterización físico-química realizada a las materias primas empleadas. Los resultados de los análisis físico-químicos y microbiológicos del producto terminado fueron satisfactorios. Se realizó un estudio de estabilidad en vida de estante durante 18 meses, con el que se pudo comprobar que la formulación obtenida es estable durante el tiempo estudiado a temperatura entre 15 y 25 °C y durante 7 d después de reconstituido y mantenido en refrigeración. El medicamento cumple con las especificaciones de calidad descritas en la USP 24.The formulation of cephalexin 250 mg was developed as a granulate for oral suspension. The humid way was used for the preparation of the granulate, taking into account the results of the physicochemical characterization of the raw materials used. The results of the physicochemical and microbiological analyses of the finished product were satisfactory. A shelf life stability study was conducted for 18 months that made possible to prove that the formulation obtained was stable during the studied time at temperatures between 15 and 25 ºC and for 7 days after being reconstituted and kept in refrigeration. The drug meets the quality specifications described in the USP 24.

  14. Mapping Irrigated Areas Using MODIS 250 Meter Time-Series Data: A Study on Krishna River Basin (India

    Directory of Open Access Journals (Sweden)

    Andrew Nelson

    2011-01-01

    Full Text Available Mapping irrigated areas of a river basin is important in terms of assessing water use and food security. This paper describes an innovative remote sensing based vegetation phenological approach to map irrigated areas and then the differentiates the ground water irrigated areas from the surface water irrigated areas in the Krishna river basin (26,575,200 hectares in India using MODIS 250 meter every 8-day near continuous time-series data for 2000–2001. Temporal variations in the Normalized Difference Vegetation Index (NDVI pattern obtained in irrigated classes enabled demarcation between: (a irrigated surface water double crop, (b irrigated surface water continuous crop, and (c irrigated ground water mixed crops. The NDVI patterns were found to be more consistent in areas irrigated with ground water due to the continuity of water supply. Surface water availability, on the other hand, was dependent on canal water release that affected time of crop sowing and growth stages, which was in turn reflected in the NDVI pattern. Double cropped and light irrigation have relatively late onset of greenness, because they use canal water from reservoirs that drain large catchments and take weeks to fill. Minor irrigation and ground water irrigated areas have early onset of greenness because they drain smaller catchments where aquifers and reservoirs fill more quickly. Vegetation phonologies of 9 distinct classes consisting of Irrigated, rainfed, and other land use classes were also derived using MODIS 250 meter near continuous time-series data that were tested and verified using groundtruth data, Google Earth very high resolution (sub-meter to 4 meter imagery, and state-level census data. Fuzzy classification accuracies for most classes were around 80% with class mixing mainly between various irrigated classes. The areas estimated from MODIS were highly correlated with census data (R-squared value of 0.86.

  15. Customized broadband Sloan-filters for the JST/T250 and JAST/T80 telescopes: measurement summary

    Science.gov (United States)

    Brauneck, Ulf; Sprengard, Ruediger; Bourquin, Sebastien; Marín-Franch, Antonio

    2018-01-01

    The Centro de Estudios de Fisica del Cosmos de Aragon will conduct a photometric sky survey with two new telescopes recently set up on the Javalambre mountain in Spain: the JST/T250 is a 2.55-m telescope with a plate scale of 22.67 arc⁢sec/mm and a 3-deg-diameter field of view (FoV) and the auxiliary telescope JAST/T80 with a 82-cm primary mirror and an FoV of 2 deg diameter. A multiple CCD (9k-by-9k array size, 10-μm pixel size) mosaic camera is used in combination with filter trays or filter wheels, each containing a multitude of filters in dimensions of 101.7×96.5 mm or 106.8×106.8 mm. For this project, Schott manufactured 56 specially designed narrow band steep-edged bandpass interference filters and five broadband Sloan-filters which were completed only recently. We report here on the results of the broadband Sloan-filters with transmission bands of 324 to 400 nm (Sloan-u), 400 to 550 nm (Sloan-g), 550 to 700 nm (Sloan-r), 695 to 850 nm (Sloan-i), and 830 to 1200 nm (Sloan-z). The filters are composed of Schott filterglasses and clearglass substrates coated with interference filters and represent an improvement of broadband Sloan filters commonly used in astronomy. In spite of the absorptive elements, the filters show maximum possible transmissions achieved by magnetron sputtered filter coatings. In addition, the blocking of the filters is better than OD5 (transmission <10 to -5) in the range 250 to 1050 nm which was achieved by combining up to three substrates. A high image quality required a low transmitted wavefront error (<λ/8 locally, respectively <λ/2 globally). We report on the spectral and interferometric results measured on the filters.

  16. Customized broadband sloan-filters for the JST/T250 and JAST/T80 telescopes: summary of results

    Science.gov (United States)

    Brauneck, U.; Sprengard, R.; Bourquin, S.; Marín-Franch, A.

    2017-09-01

    The Centro de Estudios de Fisica del Cosmos de Aragon (CEFCA) will conduct a photometric sky survey with 2 new telescopes recently setup on the Javalambre mountain in Spain: the JST/T250 is a 2.55m telescope with a plate scale of 22.67"/mm and a 3° diameter field of view (FoV) and the auxiliary telescope JAST/T80 with a 82cm primary mirror and a FoV of 2 deg diameter. A multiple CCD (9k-by-9k array size, 10μm pixel size) mosaic camera is used in combination with filter trays or filter wheels, each containing a multitude of filters in dimensions of 101.7x96.5mm or 106.8x106.8mm. For this project, SCHOTT manufactured 56 specially designed narrow band steep edged bandpass interference filters and 5 broadband sloan-filters which were completed only recently. We report here on the results of the broadband sloanfilters with transmission bands of 324-400nm (sloan-u), 400-550nm (sloan-g), 550-700nm (sloan-r), 695-850nm (sloan-i) and 830-1200nm (sloan-z). The filters are composed of SCHOTT filterglasses and clearglass substrates coated with interference filters and represent an improvement of broadband sloan filters commonly used in astronomy. Inspite of the absorptive elements, the filters show maximum possible transmissions achieved by magnetron sputtered filter coatings. In addition the blocking of the filters is better than OD5 in the range 250-1050nm. A high image quality required a low transmitted wavefront error (<λ/8 locally, respectively <λ/2 globally) which was achieved by combining up to 2 substrates. We report on the spectral and interferometric results measured on the filters.

  17. Effect of a 5000 ppm fluoride toothpaste and a 250 ppm fluoride mouth rinse on the demineralisation of dentin surfaces.

    Science.gov (United States)

    Bizhang, Mozhgan; Chun, Yong-Hee P; Winterfeld, Mai-Trinh; Altenburger, Markus J; Raab, Wolfgang H M; Zimmer, Stefan

    2009-07-23

    The purpose of this study was to test the null hypothesis that there is no difference between the effect of (1) a 5000 ppm fluoride toothpaste, and (2) a 250 ppm fluoride mouth rinse on demineralized human dentin surfaces, against the alternative hypothesis of a difference. Dentin specimens were obtained from the cervical regions of 45 extracted human third molars. Half the surface of each specimen was sealed with a self-etching adhesive system and served as the reference surface. The dentin specimens were randomly assigned to one of the three groups, 5000 ppm fluoride toothpaste (Duraphat), 250 ppm fluoride mouth rinse (Meridol) and distilled water (negative control).An intraoral appliance was made for one volunteer. In each test cycle, 15 specimens were inserted in the appliance and worn for 24 hours a day, over a period of three weeks.Once daily, the appliance was immersed in the agent being tested; either toothpaste slurry, mouth rinse or distilled water for 60 seconds.Demineralization was assessed in terms of lesion depth (microm) and mineral loss (vol. % x microm) by transversal microradiography. Data analysis was accomplished using Kolmogorov-Smirnov test and ANOVA (SPSS 12.0).Statistically significant differences for mineral loss and lesion depth were found between the toothpaste and the mouth rinse as well as between the toothpaste and the control group, but not between the mouth rinse and the control group. Within the limitations of this study, the results suggest that treatment of demineralised dentin with a toothpaste containing 5000 ppm fluoride may considerably reduce mineral loss and lesion depth on exposed dentin.

  18. 250 ORIGINAL ARTICLE

    African Journals Online (AJOL)

    boaz

    aureusstrains, among which 14 (46, 66 %) were méthicillin-resistant (MRSA). Risk factors analysis revealed that history of hospitalization, recent antibiotic intake and frequent contact with animals and livestock workers/veterinarians increase the risk of MRSA nasal carriage. Among MRSA nasal isolates, a high rate of.

  19. 250 ORIGINAL ARTICLE

    African Journals Online (AJOL)

    boaz

    vétérinaires ont été démontrées comme étant à risque de portage de Staphylococcus aureus résistant à la méticilline(SARM). ... antérieures ont été réalisées et ayant permisd'isolerdes S. aureus sur milieu culturechromogènique sélectif et la réalisation de ..... molecular characterization (mecA, femA) of our. MRSA strains to ...

  20. Foundations and anchors for a 250 m span arch bridge in la Palma Island (Canaries); Cimentaciones y anclajes para la construccion del Arco de los tilos, de 250 m. de luz, en la isla de la Palma (Canarias)

    Energy Technology Data Exchange (ETDEWEB)

    Simic Sureda, D.

    2008-07-01

    There are no simple procedures to estimate the bearing capacity of direct foundations on rock due to its anisotropy, as the criteria have to take into account different features concerning the rock discontinuities (spacing, orientation, opening, persistence,...) as well as other aspects concerning the rock matrix, particularly its strength when it is low. In this sense, the volcanic formations of the Canary Island pose important difficulties to the designer of foundations given their highly anisotropic fabric, which is the result of a complex origin where the basalt sheets alternate with fragmentary material of pyroclastic nature. This volcanic building is frequently intersected by old vents, in the guise of pipes plugged with broken fragments of low compacity. In a valley of highly dissected steep slopes of such geology an arch bridge has been designed and built with a span between supports of 250 m. This paper describes the analysis that was carried out to take into account the particularities of rock anisotropy and the foundations geometry in very steep slopes. The construction problems are also addressed in the paper, describing the grouting treatment that was needed in one of the supports due to the presence of an old vent. (Author) 7 refs.

  1. Hydrological variability in the Northern Levant: a 250 ka multiproxy record from the Yammoûneh (Lebanon sedimentary sequence

    Directory of Open Access Journals (Sweden)

    F. Gasse

    2011-11-01

    Full Text Available The Levant is a key region in terms of both long-term hydroclimate dynamics and human cultural evolution. Our understanding of the regional response to glacial-interglacial boundary conditions is limited by uncertainties in proxy-data interpretation and the lack of long-term records from different geographical settings.

    The present paper provides a 250 ka paleoenvironmental reconstruction based on a multi-proxy approach from northern Levant, derived from a 36 m lacustrine-palustrine sequence cored in the small intra-mountainous karstic Yammoûneh basin from northern Lebanon. We combined time series of sediment properties, paleovegetation, and carbonate oxygen isotopes (δc, to yield a comprehensive view of paleohydrologic-paleoclimatic fluctuations in the basin over the two last glacial-interglacial cycles. Integration of all available proxies shows that Interglacial maxima (early-mid MIS 7, MIS 5.5 and early MIS 1 experienced relatively high effective moisture, evidenced by the dominance of forested landscapes (although with different forest types associated with authigenic carbonate sedimentation in a productive waterbody. Synchronous and steep δc increases can be reconciled with enhanced mean annual moisture when changes in seasonality are taken into account. During Glacials periods (MIS 2 and MIS 6, open vegetation tends to replace the forests, favouring local erosion and detrital sedimentation. However, all proxy data reveal an overall wetting during MIS 6, while a drying trend took place during MIS4-2, leading to extremely harsh LGM conditions possibly linked to water storage as ice in the surrounding highlands. Over the past 250 ka, the Yammoûneh record shows an overall decrease in local effective water, coincident with a weakening of seasonal insolation contrasts linked to the decreasing amplitude of the eccentricity cycle.

    The Yammoûneh record is roughly consistent with long-term climatic

  2. Effects of feeding regimen on weight gain, semen characteristics, libido, and lameness in 170- to 250-kilogram Duroc boars.

    Science.gov (United States)

    Wang, C; Li, J L; Wei, H K; Zhou, Y F; Tan, J J; Sun, H Q; Jiang, S W; Peng, J

    2016-11-01

    A 2-period field trial was conducted to determine the effects of feeding regimen on weight gain, semen characteristics, libido, and lameness in 170- to 200-kg (period 1) and 200- to 250-kg (period 2) boars. Sixty-one Duroc boars were allotted to 1 of 3 dietary treatments and 15 g/d fish oil was also provided for each experimental boar, to maintain the n-6:n-3 intake ratio at approximately 6.1:1. The energy intakes of the 3 treatment groups were controlled by basing the feed intake on a corn-soybean meal-based diet (3.11 Mcal/kg of ME) to create: 1) low energy intake group (L, = 20, 7.3 Mcal/d of ME), 2) medium energy intake group (M, = 20, 7.7 Mcal/d of ME), and 3) high energy intake group (H, = 21, 8.3 Mcal/d of ME) in period 1. Feed intake was then increased to 7.6, 8.2, and 8.6 Mcal/d of ME for the 3 groups, respectively, in period 2. During the 28-wk experimental period, boar weight gain, testis volume, semen characteristics, libido, toe measurements, claw lesions, and lameness were examined, and the number of boars culled in each group was recorded to calculate the culling rate. Although there were no differences in testis volume, sperm concentration, and motility, the percentage of abnormal sperm, the percentage of claw lesions, and claw lesion scores differed among treatments ( > 0.05), and ADG was significantly increased with the increase of energy intake between the 2 periods ( 0.05). Nonetheless, the H boars took more time to mount the collection dummy and produce an ejaculate and, in particular, showed a greater percentage of lameness than the L and M boars ( < 0.05). Therefore, the medium energy intake regimen (energy intakes of 7.7 and 8.2 Mcal/d of ME with ADG of 454.5 and 375.3 g/d in 2 periods, respectively) improved the total sperm number and functional sperm number, and meanwhile decreased the occurrence of lameness in 170- to 250-kg Duroc boars.

  3. A spectroscopic study of uranyl speciation in chloride-bearing solutions at temperatures up to 250 °C

    Science.gov (United States)

    Migdisov, A. A.; Boukhalfa, H.; Timofeev, A.; Runde, W.; Roback, R.; Williams-Jones, A. E.

    2018-02-01

    The speciation of U in NaCl-bearing solutions at temperatures up to 250 °C and concentrations of NaCl up to 1.5 m has been investigated using an in situ spectroscopic technique. The recorded spectra permit us to identify the species present in the solutions as UO22+, UO2Cl+, and UO2Cl2°. UO2Cl3- is also likely present at high temperatures and NaCl concentrations, but concentrations of this species are insufficient for derivation of the formation constants. No evidence was found for species of higher ligand (Cl-) number. Thermodynamic stability constants derived for these species show fair agreement with published data for 25 °C, but differ significantly from those predicted by an earlier high-temperature study (Dargent et al., 2013), which suggested that UO2Cl42- and UO2Cl53- contribute significantly to the mass balance of uranyl chloride complexes, especially at high temperature. In contrast, our data suggest that the main uranyl-chloride complex present in aqueous solutions at T > 150 °C and concentrations of NaCl relevant to natural hydrothermal systems is UO2Cl2°. The values of the logarithms of thermodynamic formation constants (β) for the reaction UO22+ + Cl- = UO2Cl+ are 0.02, 0.25, 0.55, 1.09, 1.59, and 2.28 derived at 25, 50, 100, 150, 200, and 250 °C, respectively. For the reaction UO22+ + 2Cl- = UO2Cl2° the values of log β derived at these temperatures are 0.4, 0.58, 0.74, 1.44, 2.18, and 3.42. Values of the formation constant estimated for uranyl-chloride species predict the high concentrations of U observed by Richard et al. (2011) in fluid inclusions of the giant McArthur River unconformity-type uranium deposit.

  4. The clinical application study of bone marrow immunoscintigraphy using 99Tcm-BW250/183 in evaluating patients with aplastic anemia

    International Nuclear Information System (INIS)

    Liu Zengli; Wu Jinchang; Tang Jun; Wang Wei

    2002-01-01

    Objective: To study the clinical value of bone marrow immunoscintigraphy for evaluation of patients with aplastic anemia. Methods: Twelve patients with aplastic anemia underwent bone marrow immunoscintigraphy using 99 Tc m labelled anti-granulocyte monoclonal antibody BW250/183, 10 of them also underwent bone marrow imaging using 99 Tc m -sulfur colloid (SC) 2 - 3 days later. The semiquantitative indexes of bone marrow immunoscintigraphy of the patients were compared with those of control patients. Results: Bone marrow immunoscintigraphy was superior to 99 Tc m -SC bone marrow imaging. In patients with aplastic anemia, the accumulation of 99 Tc m -BW250/183 in bone marrow and spleen was lower and in liver and kidney was higher than those of control patients. Nine patients were found with multiple focal accumulation in bone marrow. Conclusion: Bone marrow immunoscintigraphy with 99 Tc m -BW250/183 plays an important role in evaluating patients with aplastic anemia

  5. Hydroclimatic variability in loess δDwax records from the central Chinese Loess Plateau over the past 250 ka

    Science.gov (United States)

    Wang, Zheng; An, Zhisheng; Liu, Zhonghui; Qiang, Xiaoke; Zhang, Fan; Liu, Weiguo

    2018-04-01

    This study reports hydrogen isotopic records from the central Chinese Loess Plateau (CLP) over the past 250 ka. After eliminating the influence of ice and local temperatures, the δDwax records extracted from two loess sites at Xifeng and Luochuan can be taken to represent arid/humid alternations in the hydrological environment in this marginal Asian Summer Monsoon (ASM) region; they also contain integrated information on summer precipitation patterns and the corresponding responses to these changes by predominant vegetation cover types. These arid/humid alternations show 100 ka, 40 ka and 20 ka cycles. An increase in precipitation in association with an enhanced summer monsoon has historically been taken to be the major factor driving a humid environment in the central CLP. However, hydroclimatic changes in δDwax records differ for the central CLP, central China and southern China. Over a 20 ka cycle, the influence of solar insolation on hydroclimatic changes can be shown to be consistent throughout the central CLP. However, changes in the relative location of the land and sea may have caused different hydroclimatic responses between southern China and the central CLP on a glacial-interglacial scale. The hydroclimatic variability in the central CLP would suggest that an enhanced summer monsoon due to climatic warming is the key to understanding decreased drought degree in this marginal monsoonal region.

  6. Resistance of Incoloy 800 steam generator tube to pitting corrosion in PWR secondary water at 250°C

    Energy Technology Data Exchange (ETDEWEB)

    Schvartzman, Mônica M.A.M. [Pontifícia Universidade Católica de Minas Gerais (PUC-Minas), Belo Horizonte, MG (Brazil); Albuquerque, Adriana Silva de; Esteves, Luiza; Rabello, Emerson G.; Mansur, Fábio Abud, E-mail: monicacdtn@gmail.com, E-mail: asa@cdtn.br, E-mail: luiza.esteves@cdtn.br, E-mail: egr@cdtn.br, E-mail: fametalurgica@gmail.com [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2017-07-01

    The steam generator (SG) is one of the main components of a PWR, so the performance of this type of nuclear power plant depends to a large extent on the trouble-free operation of SGs. Its degradation significantly affects the overall plant performance. Alloy 800NG (Incoloy® 800) is a nickel-iron-chromium alloy used for steam generator tubes in PWRs due to their high strength, good workability and resistance to corrosion. This behavior is attributed to the protective oxide film formed on the metal surface by contact with the high temperature pressurized water. However, chloride is one of major SG impurities that cause the breakdown of the passive film and initiate localized corrosion in passive metals as Alloy 800NG. The aim of this study is to provide information about the pitting corrosion behavior of the Incoloy® 800 steam generator tube under normal secondary circuit parameters (250 deg C and 5 MPa) and abnormal conditions of operation (presence of chloride ions in the secondary water). For this, optical microscopy, XRD and EDS analysis and electrochemical tests have been carried out under simulated PWR secondary water operating conditions. The susceptibility to pitting corrosion was evaluated using electrochemical tests and the oxide layer formed on material was examined by means of scanning electron microscopy (SEM) and energy dispersive X-ray spectrometer (EDS) analyses. (author)

  7. A gas/liquid chromatographic-mass spectrometric method for the rapid screening of 250 pesticides in aqueous matrices

    Energy Technology Data Exchange (ETDEWEB)

    Chandramouli, B.; Harvan, D.; Brittain, S.; Hass, R. [Eno River Labs, LLC. Durham, NC (United States)

    2004-09-15

    Pesticide residues in food present a potentially serious and significant cause for concern. Many pesticides have been associated with significant health effects to the nervous and endocrine systems and some have been deemed carcinogenic. There are many well-established techniques for pesticide analysis. However, commercial pesticide methods have traditionally only been available for specific pesticide families, such as chlorinated pesticides or herbicides, and at detection limits ranging from 0.05 ppb to 1 ppm in aqueous matrices. Techniques that can quickly screen for the presence/absence of pesticide residues in food matrices are critical in ensuring the safety of food and water. This paper outlines a combined Gas Chromatographic-High Resolution Mass Spectrometric (GC-HRMS) and Liquid Chromatographic Tandem Mass Spectrometric (LC-MS/MS) screening assay for 250 pesticides that was developed for use in water, and soda samples at screening levels ranging from 0.1-5 ppb. The pesticides selected have been identified by the European Union as being of concern and the target of possible legislation. The list encompasses a variety of pesticide classes and compound groupings.

  8. Mapping grassland productivity with 250-m eMODIS NDVI and SSURGO database over the Greater Platte River Basin, USA

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.; Bliss, Norman B.

    2013-01-01

    This study assessed and described a relationship between satellite-derived growing season averaged Normalized Difference Vegetation Index (NDVI) and annual productivity for grasslands within the Greater Platte River Basin (GPRB) of the United States. We compared growing season averaged NDVI (GSN) with Soil Survey Geographic (SSURGO) database rangeland productivity and flux tower Gross Primary Productivity (GPP) for grassland areas. The GSN was calculated for each of nine years (2000–2008) using the 7-day composite 250-m eMODIS (expedited Moderate Resolution Imaging Spectroradiometer) NDVI data. Strong correlations exist between the nine-year mean GSN (MGSN) and SSURGO annual productivity for grasslands (R2 = 0.74 for approximately 8000 pixels randomly selected from eight homogeneous regions within the GPRB; R2 = 0.96 for the 14 cluster-averaged points). Results also reveal a strong correlation between GSN and flux tower growing season averaged GPP (R2 = 0.71). Finally, we developed an empirical equation to estimate grassland productivity based on the MGSN. Spatially explicit estimates of grassland productivity over the GPRB were generated, which improved the regional consistency of SSURGO grassland productivity data and can help scientists and land managers to better understand the actual biophysical and ecological characteristics of grassland systems in the GPRB. This final estimated grassland production map can also be used as an input for biogeochemical, ecological, and climate change models.

  9. Efficient charge carrier injection into sub-250 nm AlGaN multiple quantum well light emitting diodes

    International Nuclear Information System (INIS)

    Mehnke, Frank; Kuhn, Christian; Guttmann, Martin; Reich, Christoph; Kolbe, Tim; Rass, Jens; Wernicke, Tim; Kueller, Viola; Knauer, Arne; Lapeyrade, Mickael; Einfeldt, Sven; Weyers, Markus; Kneissl, Michael

    2014-01-01

    The design and Mg-doping profile of AlN/Al 0.7 Ga 0.3 N electron blocking heterostructures (EBH) for AlGaN multiple quantum well (MQW) light emitting diodes (LEDs) emitting below 250 nm was investigated. By inserting an AlN electron blocking layer (EBL) into the EBH, we were able to increase the quantum well emission power and significantly reduce long wavelength parasitic luminescence. Furthermore, electron leakage was suppressed by optimizing the thickness of the AlN EBL while still maintaining sufficient hole injection. Ultraviolet (UV)-C LEDs with very low parasitic luminescence (7% of total emission power) and external quantum efficiencies of 0.19% at 246 nm have been realized. This concept was applied to AlGaN MQW LEDs emitting between 235 nm and 263 nm with external quantum efficiencies ranging from 0.002% to 0.93%. After processing, we were able to demonstrate an UV-C LED emitting at 234 nm with 14.5 μW integrated optical output power and an external quantum efficiency of 0.012% at 18.2 A/cm 2

  10. Characterization of thermochromic VO2 (prepared at 250 °C) in a wide temperature range by spectroscopic ellipsometry

    Science.gov (United States)

    Houska, J.; Kolenaty, D.; Rezek, J.; Vlcek, J.

    2017-11-01

    The paper deals with thermochromic VO2 prepared by reactive high-power impulse magnetron sputtering and characterized by spectroscopic ellipsometry. We focus on the dispersion of optical constants in a wide temperature range and on the transmittance predicted using the optical constants. While the thermochromic behavior of VO2 in itself has been reported previously (particularly above the room temperature, RT), in this paper we present (i) optical properties achieved at a low deposition temperature of 250 °C and without any substrate bias voltage (which dramatically increases the application potential of the coating) and (ii) changes of these properties not only above but also below RT (down to -30 °C). The properties include very low (for VO2) extinction coefficient at RT (0.10 at 550 nm), low transition temperature of around or even below 50 °C (compared to the frequently cited 68 °C) and high modulation of the predicted infrared transmittance (e.g. 39% at -30 °C, 30% at RT and 3.4% above the transition temperature at 2000 nm for a 100 nm thick coating on glass). The results are important for the design of thermochromic coatings, and pathways for their preparation under industry-friendly conditions, for various technological applications.

  11. T1-weighted in vivo human whole brain MRI dataset with an ultrahigh isotropic resolution of 250 μm

    Science.gov (United States)

    Lüsebrink, Falk; Sciarra, Alessandro; Mattern, Hendrik; Yakupov, Renat; Speck, Oliver

    2017-03-01

    We present an ultrahigh resolution in vivo human brain magnetic resonance imaging (MRI) dataset. It consists of T1-weighted whole brain anatomical data acquired at 7 Tesla with a nominal isotropic resolution of 250 μm of a single young healthy Caucasian subject and was recorded using prospective motion correction. The raw data amounts to approximately 1.2 TB and was acquired in eight hours total scan time. The resolution of this dataset is far beyond any previously published in vivo structural whole brain dataset. Its potential use is to build an in vivo MR brain atlas. Methods for image reconstruction and image restoration can be improved as the raw data is made available. Pre-processing and segmentation procedures can possibly be enhanced for high magnetic field strength and ultrahigh resolution data. Furthermore, potential resolution induced changes in quantitative data analysis can be assessed, e.g., cortical thickness or volumetric measures, as high quality images with an isotropic resolution of 1 and 0.5 mm of the same subject are included in the repository as well.

  12. Ab-externo AAV-mediated gene delivery to the suprachoroidal space using a 250 micron flexible microcatheter.

    Directory of Open Access Journals (Sweden)

    Marc C Peden

    2011-02-01

    Full Text Available The current method of delivering gene replacement to the posterior segment of the eye involves a three-port pars plana vitrectomy followed by injection of the agent through a 37-gauge cannula, which is potentially wrought with retinal complications. In this paper we investigate the safety and efficacy of delivering adeno-associated viral (AAV vector to the suprachoroidal space using an ab externo approach that utilizes an illuminated microcatheter.6 New Zealand White rabbits and 2 Dutch Belted rabbits were used to evaluate the ab externo delivery method. sc-AAV5-smCBA-hGFP vector was delivered into the suprachoroidal space using an illuminated iTrackTM 250A microcatheter. Six weeks after surgery, the rabbits were sacrificed and their eyes evaluated for AAV transfection using immunofluorescent antibody staining of GFP.Immunostaining of sectioned and whole-mounted eyes demonstrated robust transfection in all treated eyes, with no fluorescence in untreated control eyes. Transfection occurred diffusely and involved both the choroid and the retina. No apparent adverse effects caused by either the viral vector or the procedure itself could be seen either clinically or histologically.The ab externo method of delivery using a microcatheter was successful in safely and effectively delivering a gene therapy agent to the suprachoroidal space. This method presents a less invasive alternative to the current method of virally vectored gene delivery.

  13. MODIS 250m burned area mapping based on an algorithm using change point detection and Markov random fields.

    Science.gov (United States)

    Mota, Bernardo; Pereira, Jose; Campagnolo, Manuel; Killick, Rebeca

    2013-04-01

    Area burned in tropical savannas of Brazil was mapped using MODIS-AQUA daily 250m resolution imagery by adapting one of the European Space Agency fire_CCI project burned area algorithms, based on change point detection and Markov random fields. The study area covers 1,44 Mkm2 and was performed with data from 2005. The daily 1000 m image quality layer was used for cloud and cloud shadow screening. The algorithm addresses each pixel as a time series and detects changes in the statistical properties of NIR reflectance values, to identify potential burning dates. The first step of the algorithm is robust filtering, to exclude outlier observations, followed by application of the Pruned Exact Linear Time (PELT) change point detection technique. Near-infrared (NIR) spectral reflectance changes between time segments, and post change NIR reflectance values are combined into a fire likelihood score. Change points corresponding to an increase in reflectance are dismissed as potential burn events, as are those occurring outside of a pre-defined fire season. In the last step of the algorithm, monthly burned area probability maps and detection date maps are converted to dichotomous (burned-unburned maps) using Markov random fields, which take into account both spatial and temporal relations in the potential burned area maps. A preliminary assessment of our results is performed by comparison with data from the MODIS 1km active fires and the 500m burned area products, taking into account differences in spatial resolution between the two sensors.

  14. On Improving the Quality of Gas Tungsten Arc Welded 18Ni 250 Maraging Steel Rocket Motor Casings

    Science.gov (United States)

    Gupta, Renu N.; Raja, V. S.; Mukherjee, M. K.; Narayana Murty, S. V. S.

    2017-10-01

    In view of their excellent combination of strength and toughness, maraging steels (18Ni 250 grade) are widely used for the fabrication of large sized solid rocket motor casings. Gas tungsten arc welding is commonly employed to fabricate these thin walled metallic casings, as the technique is not only simple but also provides the desired mechanical properties. However, sometimes, radiographic examination of welds reveals typical unacceptable indications requiring weld repair. As a consequence, there is a significant drop in weld efficiency and productivity. In this work, the nature and the cause of the occurrence of these defects have been investigated and an attempt is made to overcome the problem. It has been found that weld has a tendency to form typical Ca and Al oxide inclusions leading to the observed defects. The use of calcium fluoride flux has been found to produce a defect free weld with visible effect on weld bead finish. The flux promotes the separation of inclusions, refines the grain size and leads to significant improvement in mechanical properties of the weldment.

  15. Shielding data for 100-250 MeV proton accelerators double differential neutron distributions and attenuation in concrete

    CERN Document Server

    Agosteo, S; Mereghetti, A; Silari, M; Zajacova, Z

    2007-01-01

    Double differential distributions of neutrons produced by 100, 150, 200 and 250 MeV protons stopped in a thick iron target were simulated with the FLUKA Monte Carlo code at four emission angles: forward, 45°, transverse and 135° backwards. The attenuation in ordinary concrete of the dose equivalent due to secondary neutrons, protons, photons and electrons was calculated. Some of the resulting attenuation curves are best fitted by a double-exponential function rather than a single-exponential. The effect of various approximations introduced in the simulations is thoroughly discussed. The contribution to the total ambient dose equivalent from photons and protons is usually limited to a few percent, except in the backward direction where photons contribute more than 10% and up to 35% to the total dose for a shield thickness of 1 – 2 m. Source terms and attenuation lengths are given as a function of energy and emission angle, along with fit to the Monte Carlo data. An extensive comparison is made of values ob...

  16. Design, fabrication, commissioning, and testing of a 250 g/s, 2-K helium cold compressor system

    International Nuclear Information System (INIS)

    V. Ganni; D. M. Arenius; B. S. Bevins; W. C. Chronis; J. D. Creel; J. D. Wilson Jr.

    2002-01-01

    In June 1999 the Thomas Jefferson National Accelerator Facility (TJNAF) Cryogenic Systems Group had completed the design, fabrication, and commissioning of a cold compressor system capable of pumping 250 g/s of 2-K helium vapor to a pressure above 1 bar. The 2-K cold box consists of five stages of centrifugal variable speed compressors with LN2 cooled drive motors and magnetic bearings, a plate fin heat exchanger, and an LN2 shield system. The new 2-K cold box (referred to as the SCN) was built as a redundant system to an existing four stage cold compressor SCM cold box that was commissioned in May 1994. The SCN has been in continuous service supporting the facility experiments since commissioning. This system has achieved a significant improvement in the total 2-K refrigeration system capacity and stability and has substantially increased the operating envelope both in cold compressor flow and operating pressure range. This paper describes the cold box configuration and the experience s in the design, fabrication, commissioning and performance evaluation. The capacity of the system for various operating pressures (0.040 to 0.025 bar at the load corresponding to a total compressor pressure ratio of 28 to 54) is presented. An effort is made to characterize the components and their operating data over the tested range. This includes the return side pressure drop in the distribution system, the heat exchanger, and the cold compressor characteristics. The system design parameters and their effects on performance are outlined

  17. Avaliação do perfil de dissolução de comprimidos de ciprofloxacino 250 mg comercializados como similares no Brasil Dissolution profile evaluation of ciprofloxacin 250 mg tablets marketed as similar drugs in Brazil

    Directory of Open Access Journals (Sweden)

    Nilson Oliveira Gonçalves Pita

    2004-09-01

    Full Text Available O presente trabalho avaliou, in vitro, oito especialidades farmacêuticas contendo ciprofloxacino (250 mg, sendo o produto C, o medicamento referência (Cipro® fabricado pela Bayer® S.A. e A, B, D, E, F, G e H medicamentos considerados similares. Além do teste de dissolução preconizado pela Farmacopéia americana, foi traçado o perfil de dissolução de cada amostra a partir do qual foram calculados parâmetros de eficiência de dissolução (ED. O preço máximo ao consumidor também foi levantado, para que fosse possível compará-lo com o desempenho dos produtos. Os resultados obtidos demonstram que todas as amostras atendem aos critérios especificados pelo teste de dissolução descrito na USP 24 ed., mas somente os produtos B, C, E e H foram aprovados no primeiro estágio (S1. Após tratamento estatístico empregando-se ANOVA e teste de Tukey, para os valores de eficiência de dissolução, notou-se que os produtos A e D, B e C, B e E e C e H são semelhantes quanto à liberação do fármaco in vitro. Entretanto, os produtos que mostraram melhor desempenho quanto à liberação de ciprofloxacino in vitro não são os mesmos que se apresentam como melhor opção de custo ao consumidor.The present study has assessed, in vitro, eight pharmaceutical brands containing ciprofloxacin (250 mg. The product C is the reference drug (Cipro® - Bayer® S/A and A, B, D, E, F, G and H are similar drugs. The following physicochemical tests have been carried out: dissolution test and dissolution profile, from which dissolution efficiency (DE have been calculate. The maximum price for consumer has also been obtained, in order that it was possible to compare it with the performance of the products. The results show that all the produts comply with USP specifications, but only the products, B, C, E and H have been approved on the first stage (S1. After statistic treatment, by applying ANOVA and Tukey test for DE values, it has been noted that the

  18. Evaluation of mechanical properties of Z250 composite resin light-cured by different methods Avaliação de propriedades mecânicas da resina composta Z250 fotoativada com diferentes métodos

    Directory of Open Access Journals (Sweden)

    Andresa Carla Obici

    2005-12-01

    Full Text Available This study evaluated some mechanical parameters of Z250 composite resin using different light-curing methods. Ten specimens were prepared for each mechanical test group with different dimensions according to the test. Light-curing was performed by: a. continuous light (800mW/cm²-40s; b. exponential light (0-800mW/cm²-40s; c. intermittent light (2s-600mW/cm²; 2s without light-80s; d. stepped light (10s-150mW/cm²; 30s-650mW/cm²; e. PAC (1320mW/cm²-3s; f. LED (350mW/cm²-40s. After 24 ± 1 h, the specimens were loaded at a crosshead speed of 0.5 mm/min until fracture. The mechanical properties were calculated and analyzed by ANOVA and Tukey test (5%. The results showed that the highest compressive strength values were found for the continuous, exponential, intermittent and stepped light methods, whereas PAC and LED obtained the lowest values. LED, stepped light, PAC, exponential and continuous light presented the highest values for diametral tensile strength. The intermittent light showed the lowest value, which was significantly lower than the value obtained for LED only. Flexural strength results were not significantly different between all light-curing methods. Finally, the highest modulus of elasticity values were obtained for LED, exponential, continuous and intermittent light, whereas PAC and stepped light showed the lowest values. The mechanical properties were affected by light-curing methods employed.Este estudo avaliou algumas propriedades mecânicas da resina composta Z250 usando diferentes métodos de fotoativação. Dez amostras foram preparadas para cada grupo, com diferentes dimensões de acordo com o ensaio. Os métodos de fotoativação foram: a luz contínua (800mW/cm²-40s; b luz exponencial (0-800mW/cm²-40s; c luz intermitente (2s-600mW/cm²; 2s sem luz-80s; d dupla intensidade (10s-150mW/cm²; 30s-650mW/cm²; e PAC (1320mW/cm²-3s; f LED (350mW/cm²-40s. Após 24 ± 1 h, as amostras foram carregadas até fraturar (v=0

  19. 76 FR 36395 - Airworthiness Directives; Piper Aircraft, Inc. Models PA-24, PA-24-250, and PA-24-260 Airplanes

    Science.gov (United States)

    2011-06-22

    ..., Inc. Models PA-24, PA- 24-250, and PA-24-260 Airplanes AGENCY: Federal Aviation Administration (FAA... September 15, 2004. This SAIB alerted owners and operators of Piper Aircraft, Inc. (Piper) Models PA-23, PA-24, PA-30, and PA-39 airplanes of potential corrosion of the stabilator torque tube, attach fittings...

  20. 30 CFR 250.1156 - What steps must I take to receive approval to produce within 500 feet of a unit or lease line?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What steps must I take to receive approval to... MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Requirements Approvals Prior to Production § 250.1156 What steps must...

  1. Cobalt and molybdenum activated electrodes in foam based alkaline electrolysis cells at 150-250 °C and 40 bar

    DEFF Research Database (Denmark)

    Allebrod, Frank; Chatzichristodoulou, Christodoulos; Mogensen, Mogens Bjerg

    2014-01-01

    A new type of alkaline electrolysis cells with nickel foam based gas diffusion electrodes and KOH (aq) immobilized in mesoporous SrTiO3 has been developed and tested at temperatures of 150 C, 200 C and 250 C at a pressure of 40 bar. Two cells have been characterized during the 270 h long test...

  2. Soil and Terrain Database for Upper Tana River Catchment (version 1.1) - scale 1:250,000 (SOTER_UT_v1.1)

    NARCIS (Netherlands)

    Dijkshoorn, J.A.; Macharia, P.; Kempen, B.

    2014-01-01

    The Soil and Terrain database for the Upper Tana River Catchment (version 1.1) (SOTER_UT_v1.1) at scale 1:250,000 was compiled to support the Green Water Credits (GWC) programme by creating a primary SOTER dataset for a hydrology assessment of the basin. The Kenya Soil Survey of the Kenya

  3. Comparison of CO2 and Nd:YAG laser welding of grade 250 maraging steel, IIW doc. II-A-173-06

    CSIR Research Space (South Africa)

    Van Rooyen, C

    2006-11-01

    Full Text Available :YAG Laser Welding of Grade 250 Maraging Steel IIW Doc. II-A-173-06 C. van Rooyen1, H.P. Burger1, P. Kazadi1, C. Kriek2 1National Laser Centre-CSIR, Meiring Naude Rd, Pretoria, South Africa 2Denel Land Systems, Western Cape, Reeb Rd, Firgrove, South...

  4. MODIS/Terra Cloud Mask and Spectral Test Results 5-Min L2 Swath 250m and 1km V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Terra Cloud Mask and Spectral Test Results 5-Min L2 Swath 250m and 1km (MOD35_L2). MODIS was launched aboard the Terra satellite on December 18, 1999 (10:30 am...

  5. Inclusive production of π0 mesons in π+p-,K+p- and pp interactions at 250 GeV/c

    International Nuclear Information System (INIS)

    Adamus, M.A.; Azhinenko, I.V.

    1986-01-01

    Data on inclusive π 0 production in the forward hemisphere at Feynman variable (x > 0.025) in the center-of-inertia system in π + p, K + p, and pp interactions at 250 GeV/c are presented. These data are compared to the data at lower energies and interpreted in terms of quark-parton models

  6. NIR-Red Spectra-Based Disaggregation of SMAP Soil Moisture to 250 m Resolution Based on SMAPEx-4/5 in Southeastern Australia

    Directory of Open Access Journals (Sweden)

    Nengcheng Chen

    2017-01-01

    Full Text Available To meet the demand of regional hydrological and agricultural applications, a new method named near infrared-red (NIR-red spectra-based disaggregation (NRSD was proposed to perform a disaggregation of Soil Moisture Active Passive (SMAP products from 36 km to 250 m resolution. The NRSD combined proposed normalized soil moisture index (NSMI with SMAP data to obtain 250 m resolution soil moisture mapping. The experiment was conducted in southeastern Australia during SMAP Experiments (SMAPEx 4/5 and validated with the in situ SMAPEx network. Results showed that NRSD performed a decent downscaling (root-mean-square error (RMSE = 0.04 m3/m3 and 0.12 m3/m3 during SMAPEx-4 and SMAPEx-5, respectively. Based on the validation, it was found that the proposed NSMI was a new alternative indicator for denoting the heterogeneity of soil moisture at sub-kilometer scales. Attributed to the excellent performance of the NSMI, NRSD has a higher overall accuracy, finer spatial representation within SMAP pixels and wider applicable scope on usability tests for land cover, vegetation density and drought condition than the disaggregation based on physical and theoretical scale change (DISPATCH has at 250 m resolution. This revealed that the NRSD method is expected to provide soil moisture mapping at 250-resolution for large-scale hydrological and agricultural studies.

  7. Universal description of inelastic and non(single)-diffractive multiplicity distributions in pp collisions at 250, 360 and 800 GeV/c

    International Nuclear Information System (INIS)

    Krasznovszky, S.; Wagner, I.

    1987-06-01

    A distribution function is proposed for multiplicity in accordance with the stochastic number evolution. This function gives a universal description of inelastic and nondiffractive multiplicity distributions in pp collisions at 250, 360 and 800 GeV/c. The negative binomial distribution fails in the description of inelastic data. (author)

  8. 30 CFR 250.1740 - How must I verify that the site of a permanently plugged well, removed platform, or other removed...

    Science.gov (United States)

    2010-07-01

    ... Section 250.1740 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL...: (1) Drag a trawl over the site; (2) Scan across the location using sonar equipment; (3) Inspect the...) Drag a trawl over the site; (2) Scan across the site using sonar equipment; or (3) Use another method...

  9. Determination of Hydrogen Diffusion Coefficients in Fused Silica From 23 to 250°C Using Raman Spectroscopy

    Science.gov (United States)

    Shang, L.; Chou, I.; Lu, W.; Burruss, R. C.

    2008-12-01

    The oxygen buffer technique is routinely used in experimental studies of redox sensitive geochemical reactions at elevated pressures (P) and temperatures (T). However, this technique is limited to T above about 400°C due to the low permeability of sample containers (Pt or Ag-Pd alloys) to hydrogen at lower T. Preliminary results of Chou et al. (Geochim. Cosmochim. Acta, 2008, doi:10.1016/j.gca.2008.07.030) indicate that the use of fused silica capillary (FSC) container may extend this technique to lower T. In this study, hydrogen diffusion coefficients (D) in FSC were determined from 23 to 250°C by measuring the loss of hydrogen from the FSC containers (0.3 mm OD, 0.1 mm ID, and ~10 mm long) with Raman spectroscopy using CO2 as an internal standard. First, CO2 was loaded cryogenically in a FSC capsule (Chou et al., ibid.). The capsule was then inserted in a protective ceramic tube, sealed in a gold capsule containing Fe powder and water, and heated at 300°C under 100 MPa of Ar external P in a cold-seal pressure vessel for several days allowing H2 to diffuse into the capsule. After quench, the Raman spectra were collected and the initial relative concentration of hydrogen in the silica capsule was derived from the peak height ratios between H2 (near 587 cm-1) and CO2 (near 1387 cm- 1). The sample capsule was then heated at a fixed T at one atmosphere to let H2 diffuse out of the capsule, and the changes of hydrogen concentration were monitored by Raman spectroscopy after quench. This process was repeated with different heating durations at 23 (room T), 50, 102, 157, 200, and 250°C. The values of D (in cm2s-1) in FSC were obtained by fitting the observed changes of hydrogen concentration to an equation based on Fick's second law. Our results can be represented by: Ln D (±0.14) = (-39810/RT) - 9.5491 (r2 = 0.9985) where R is the gas constant, and T in Kelvin. The slope corresponds to an activation energy of 39.81 kJ/mol. Our D values are about a half order of

  10. Study of the stability of the ground states and K-isomeric states of 250Fm and 254102 against spontaneous fission

    International Nuclear Information System (INIS)

    Lazarev, Yu.A.; Lobanov, Yu.V.; Sagajdak, R.N.; Utenkov, V.K.; Kharitonov, Yu.P.; Shirokovskij, I.V.; Tret'yakova, S.P.; Oganessyan, Yu.Ts.

    1988-01-01

    By employing the 249 Cf( 4 He, 3n) and 208 Pb( 48 Ca,2n) reactions, experiments to study the stability against spontaneous fission of the nuclides 250 Fm and 254 102 as well as of the two-quasi-particle (2 q-p) K isomers 250 Fm (T 1/2 =1,8±0,1 s) and 254 102 (T 1/2 =0,28±0,04 s) have been performed. The groundstate spontaneous fission of the two nuclides has been discovered and the corresponding branching ratios b sf and partial half-lives T sf , respectively, have been determined to be: (6,9±1,0)x10 -5 , 0,83±0,15 yr for 250 Fm; (1,7±0,5)x10 -3 , (3,2±0,9)x10 4 s for 254 102. As a by-product of these studies, new data about cross sections of the 206,208 Pb( 48 Ca,xn) reactions have been obtained. Experiments designed to search for the spontaneous fission of the 2 q-p K-isometric states in 250 Fm and 254 102 have not revealed the effect in question. The lower limits of the ratios of the partial spontaneous fission half-lives for the 2 q-p K-isomeric states to those for the respective ground states, T * sf /T sf , have been established to be≥10 -1 for 250m Fm/ 250 Fm and ≥5x10 -3 for 254m 102/ 254 102. This means that the stability of the 2 q-p K-isomeric states in 250 Fm and 254 102 against spontaneous fission is practically not inferior to that of the ground states of these nuclei. In accord with the experimental findings, the theoretical estimates of T * sf /T sf made in the present paper show that, due to the influence of the specialization and blocking effects on the potential energy and the effective mass associated with fission, spontaneous fission from 2 q-p K-isomeric states cannot be facilitated but, on the contrary, should be essentially hindered compared with ground-state spontaneous fission

  11. The analysis of pilot-plant products for copper, zinc, and lead with the telsec lab-x-250 analyser

    International Nuclear Information System (INIS)

    Domel, G.

    1977-01-01

    Suites of sulphide material representative of copper, zinc, and lead concentrates, as well as 'intermediate' products, low-grade material, and tailing samples, were analysed with the Telsec Lab-X-250 Analyser, which is a radio-isotope x-rayfluorescence instrument using 'balanced' filters for energy selection. A brief description of the instrument is given, stress being laid on the principle of 'balanced' filters. The determination of optimum instrumental parameters is described, and diagrams are provided to demonstrate the efficacy of energy selection. Correlation diagrams are given for all three elements in each of the materials analysed. The scatter of data points encountered is examined in terms of possible spectral interference and matrix variation. It was found that, within specified limits of acceptability, all three elements could be determined satisfactorily in copper and lead concentrates and in low-grade material. Zinc concentrates could be analysed only for zinc. The mechanisms of the spectral interference effects peculiar to the use of balanced filters are discussed, and a correction procedure is described and applied to improve the correlation for copper in the presence of a high zinc content. It is shown that the poor correlation found for 'intermediate' products and for lead in zinc concentrates is mainly due to matrix variations. The concentration range covered, the sensitivity, the precision, and, where applicable, the detectionlimits are tabulated for all three elements and all types of material analysed. A comparison of the results obtained with the Analyser and those obtained by atomic-absorption spectrophotometry is provided [af

  12. On the masculinization of population: The contribution of demographic development -- A look at sex ratios in Sweden over 250 years

    Directory of Open Access Journals (Sweden)

    Thomas Spoorenberg

    2016-06-01

    Full Text Available Background: Almost everywhere, women live longer than men, but the world population includes increasingly more men than women. This fact is observed not only in populations where gender-based discrimination is practised, but also in developed countries like Sweden. Objective: Whereas discrimination against female infants and women is usually given as an explanation for this paradox, demographic development (through improved survival also plays a role. This study examines the largely unnoticed role of demographic development in the masculinization of population, taking the case of Sweden. Methods: Using high-quality data from the Human Mortality Database for Sweden over the last 250 years, changes in the sex ratio at various ages are described and linked to the continuing survival gains achieved over the mortality transition. Results: Thanks to the reduction of secular mortality in Sweden, the natural sex imbalance observed at birth has been progressively prolonged later in life, and the age at which women outnumber men has been postponed to older ages. Similar developments are found in Norway and Denmark. Conclusions: The general decline of mortality is one of humanity's biggest achievements, but the accompanying change in age- and sex-specific survival patterns, coupled with the natural sex imbalance at birth, influences the age and sex composition of a population and, therefore, the sex ratio at successive ages. In a world where each new generation can expect to enjoy a longer life than the previous one, an increasing number of men can also be expected. Contribution: The role of demographic development in the masculinization of population has remained largely unnoticed so far.

  13. Top-down modulation of visual processing and knowledge after 250 ms supports object constancy of category decisions

    Directory of Open Access Journals (Sweden)

    Haline E. Schendan

    2015-09-01

    Full Text Available People categorize objects slowly when visual input is highly impoverished instead of optimal. While bottom-up models may explain a decision with optimal input, perceptual hypothesis testing (PHT theories implicate top-down processes with impoverished input. Brain mechanisms and the time course of PHT are largely unknown. This event-related potential study used a neuroimaging paradigm that implicated prefrontal cortex in top-down modulation of occipitotemporal cortex. Subjects categorized more impoverished and less impoverished real and pseudo objects. PHT theories predict larger impoverishment effects for real than pseudo objects because top-down processes modulate knowledge only for real objects, but different PHT variants predict different timing. Consistent with parietal-prefrontal PHT variants, around 250 ms, the earliest impoverished real object interaction started on an N3 complex, which reflects interactive cortical activity for object cognition. N3 impoverishment effects localized to both prefrontal and occipitotemporal cortex for real objects only. The N3 also showed knowledge effects by 230 ms that localized to occipitotemporal cortex. Later effects reflected (a word meaning in temporal cortex during the N400, (b internal evaluation of prior decision and memory processes and secondary higher-order memory involving anterotemporal parts of a default mode network during posterior positivity (P600, and (c response related activity in posterior cingulate during an anterior slow wave (SW after 700 ms. Finally, response activity in supplementary motor area during a posterior SW after 900 ms showed impoverishment effects that correlated with RTs. Convergent evidence from studies of vision, memory, and mental imagery which reflects purely top-down inputs, indicates that the N3 reflects the critical top-down processes of PHT. A hybrid multiple-state interactive, PHT and decision theory best explains the visual constancy of object cognition.

  14. ICDP project DeepCHALLA: reconstructing East African climate change and environmental history over the past 250,000 years

    Science.gov (United States)

    Verschuren, Dirk; Van Daele, Maarten; Wolff, Christian; Waldmann, Nicolas; Meyer, Inka; Ombori, Titus; Peterse, Francien; O'Grady, Ryan; Schnurrenberger, Doug; Olago, Daniel

    2017-04-01

    Sediments on the bottom of Lake Challa, a 92-meter deep crater lake on the border of Kenya and Tanzania near Mt. Kilimanjaro, contain a uniquely long and continuous record of past climate and environmental change. The near-equatorial location and exceptional quality of this natural archive provide great opportunities to study tropical climate variability at both short (inter-annual to decadal) and long (glacial-interglacial) time scales; and the influence of this climate variability on the region's freshwater resources, the functioning of terrestrial ecosystems, and the history of the East African landscape in which modern humans (our species, Homo sapiens) evolved and have lived ever since. Supported in part by the International Continental Scientific Drilling Programme (ICDP), the DeepCHALLA project has now recovered the sediment record of Lake Challa down to 214.8 meter below the lake floor, with almost certain 100% cover of the uppermost 121.3 meter (ca.150,000 year BP to present) and estimated 85% cover over the lower part of the sequence, down to the lowermost distinct reflector in the available seismic stratigraphy. This reflector represents a 2 meter thick layer of volcanic sand and silt deposited ca.250,000 years ago, and overlies still older silty lacustrine clays deposited during early lake development. Down-hole logging produced continuous profiles of in-situ sediment composition that confer an absolute depth scale to both the recovered cores and their three-dimensional representation in seismic stratigraphy. As readily observed through the transparent core liners, Lake Challa sediments are finely laminated throughout most of the recovered sequence. Combined with the great time span, the exquisite temporal resolution of these sediments promises to greatly increase our understanding of tropical climate and ecosystem dynamics, and create a long-awaited equatorial counterpart to the high-latitude climate records extracted from the ice sheets of Greenland

  15. Top-down modulation of visual processing and knowledge after 250 ms supports object constancy of category decisions.

    Science.gov (United States)

    Schendan, Haline E; Ganis, Giorgio

    2015-01-01

    People categorize objects more slowly when visual input is highly impoverished instead of optimal. While bottom-up models may explain a decision with optimal input, perceptual hypothesis testing (PHT) theories implicate top-down processes with impoverished input. Brain mechanisms and the time course of PHT are largely unknown. This event-related potential study used a neuroimaging paradigm that implicated prefrontal cortex in top-down modulation of occipitotemporal cortex. Subjects categorized more impoverished and less impoverished real and pseudo objects. PHT theories predict larger impoverishment effects for real than pseudo objects because top-down processes modulate knowledge only for real objects, but different PHT variants predict different timing. Consistent with parietal-prefrontal PHT variants, around 250 ms, the earliest impoverished real object interaction started on an N3 complex, which reflects interactive cortical activity for object cognition. N3 impoverishment effects localized to both prefrontal and occipitotemporal cortex for real objects only. The N3 also showed knowledge effects by 230 ms that localized to occipitotemporal cortex. Later effects reflected (a) word meaning in temporal cortex during the N400, (b) internal evaluation of prior decision and memory processes and secondary higher-order memory involving anterotemporal parts of a default mode network during posterior positivity (P600), and (c) response related activity in posterior cingulate during an anterior slow wave (SW) after 700 ms. Finally, response activity in supplementary motor area during a posterior SW after 900 ms showed impoverishment effects that correlated with RTs. Convergent evidence from studies of vision, memory, and mental imagery which reflects purely top-down inputs, indicates that the N3 reflects the critical top-down processes of PHT. A hybrid multiple-state interactive, PHT and decision theory best explains the visual constancy of object cognition.

  16. Complication Rates and Patency of Radiologically Guided Mushroom Gastrostomy, Balloon Gastrostomy, and Gastrojejunostomy: A Review of 250 Procedures

    International Nuclear Information System (INIS)

    Yip, Doris; Vanasco, Matthew; Funaki, Brian

    2004-01-01

    To compare complication rates and tube performance of percutaneous mushroom gastrostomy, balloon gastrostomy, and gastrojejunostomy. Between September 9, 1999 and April 23, 2001, 203 patients underwent 250 radiologically guided percutaneous gastrostomy and gastrojejunostomy procedures. Follow-up was conducted through chart reviews and review of our interventional radiology database. Procedural and catheter-related complications were recorded. Chi-square statistical analysis was performed. In patients receiving mushroom-retained gastrostomy catheters (n = 114), the major complication rate was 0.88% (n = 1), the minor complication rate was 5.3% (n = 6), and the tube complication rate was 4.4% (n = 5). In patients receiving balloon-retained gastrostomy tubes (n = 67), the major complication rate was 0, the minor complication rate was 4.5% (n = 3), and the tube complication rate was 34.3% (n = 23). In patients receiving gastrojejunostomy catheters (n = 69), the major complication rate was 1.4% (n = 1), the minor complication rate was 2.9% (n = 2), and the tube complication rate was 34.8% (n = 24). No statistically significant differences were found between procedural or peri-procedural complications among the different types of tubes. Mushroom-retained catheters had significantly fewer tube complications (p < 0.01). Percutaneous gastrostomy and gastrojejunostomy have similar procedural and peri-procedural complication rates. Mushroom gastrostomy catheters have fewer tube-related complications compared with balloon gastrostomy and gastrojejunostomy catheters. In addition, mushroom-retained catheters exhibit the best overall long-term tube patency and are therefore the gastrostomy catheter of choice

  17. Enhance the anti-renca carcinoma effect of a DNA vaccine targeting G250 gene by co-expression with cytotoxic T-lymphocyte associated antigen-4(CTLA-4).

    Science.gov (United States)

    Zhao, Youguang; Wei, Zhitao; Yang, Hang; Li, Xiaowei; Wang, Qiwu; Wang, Liang; Li, Shadan

    2017-06-01

    Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a negative regulator of T cell activation, which competes with CD28 for B7.1/B7.2 binding with a greater affinity. Co-expression specific antigens and extracellular domain of CTLA4 represents a promising approach to increase the immunogenicity of DNA vaccines. In this study, we evaluated this interesting approach for its enhancement on G250/MN/CA IX (G250)-specific immune responses and its anti-tumor effects in renal carcinoma mice model. Consequently, we constructed a DNA vaccine containing the G250 and the CTLA-4 gene. Vaccination with the co-expression DNA not only induced much higher level of anti-CTLA4 and anti-G250 antibody, but also increased G250-specific T cell response in mice. To evaluate the anti-tumor efficacy of the plasmids, murine models with G250-expressing tumors were generated. After injection into the tumor-bearing mouse model, the plasmid carrying the co-expression gene of CTLA4 and G250 showed stronger inhibition of tumor growth than the plasmid expressing CTLA4 or G250 alone. These observations emphasize the potential of the CTLA4 and G250 co-expression DNA vaccine, which could represent a promising approach for tumor immunotherapy. Copyright © 2017. Published by Elsevier Masson SAS.

  18. Susceptibility of Granite Rock to scCO2/Water at 200 degrees C and 250 degrees C

    Energy Technology Data Exchange (ETDEWEB)

    Sugama, T.; Gill, S., Ecker, L., Butcher, T., Warren, J.

    2011-01-01

    Granite rock comprising anorthoclase-type albite and quartz as its major phases and biotite mica as the minor one was exposed to supercritical carbon dioxide (scCO{sub 2})/water at 250 C and 13.78 MPa pressure for 104 hours. For comparison purpose, four other rocks, albite, hornblende, diorite, and quartz, also were exposed. During the exposure of granite, ionic carbonic acid, known as the wet carbonation reactant, preferentially reacted with anorthoclase-type albite and biotite, rather than with quartz. The susceptibility of biotite to wet carbonation was higher than that of anorthoclase-type albite. All the carbonation by-products of anorthoclase-type albite were amorphous phases including Na- and K-carbonates, a kaolinite clay-like compound, and silicon dioxide, while wet carbonation converted biotite into potassium aluminum silicate, siderite, and magnesite in crystalline phases and hydrogen fluoride (HF). Three of these reaction by-products, Na- and K-carbonates and HF, were highly soluble in water. Correspondingly, the carbonated top surface layer, about 1.27 mm thick as carbonation depth, developed porous microstructure with numerous large voids, some of which have a size of {>=} 10 {mu}m, reflecting the erosion of granite by the leaching of these water-soluble reaction by-products. Comparing with this carbonation depth, its depth of other minerals was considerable lower, particularly, for hornblende and diorite with 0.07 and 0.02 mm, while no carbonate compound was detected in quartz. The major factor governing these low carbonation depths in these rocks was the formation of water-insensitive scale-like carbonate by-products such as calcite (CaCO{sub 3}), siderite (FeCO{sub 3}), and magnesite (MgCO{sub 3}). Their formation within the superficial layer of these minerals served as protective barrier layer that inhibits and retards further carbonation of fresh underlying minerals, even if the exposure time was extended. Thus, the coverage by this barrier layer

  19. A global census of continental rift activity since 250 Ma reveals a missing element of the deep carbon cycle

    Science.gov (United States)

    Brune, Sascha; Williams, Simon; Müller, Dietmar

    2017-04-01

    The deep carbon cycle connects CO2 concentrations within the atmosphere to the vast carbon reservoir in Earth's mantle: subducted lithosphere carries carbon into the mantle, while extensional plate boundaries and arc volcanoes release it back to Earth's surface. The length of plate boundaries thereby exerts first-order control on global CO2 fluxes on geological time scales. Here we provide a global census of rift length from the Triassic to present day, combining a new plate reconstruction analysis technique with data from the geological rift record. We find that the most extensive rift phase during the fragmentation of Pangea occurred in the Jurassic/Early Cretaceous with extension along the South Atlantic (9700 km) and North Atlantic rifts (9100 km), within East Gondwana (8500 km), the failed African rift systems (4900 km), and between Australia and Antarctica (3700 km). The combined extent of these and other rift systems amounts to more than 50.000 km of simultaneously active continental rifts. During the Late Cretaceous, in the aftermath of this massive rift episode, the global rift length dropped by 60% to 20.000 km. We further show that a second pronounced rift episode starts in the Eocene with global rift lengths of up to 30.000 km. It is well-accepted that volcanoes at plate boundaries release large amounts of CO2 from the Earth's interior. Recent work, however, highlights the importance of deep-cutting faults and diffuse degassing on CO2 emissions in the East African Rift, which appear to be comparable to CO2 release rates at mid-ocean ridges worldwide. Upscaling measured CO2 fluxes from East Africa to all concurrently active global rift zones with due caution, we compute the first-order history of cumulative rift-related CO2 degassing rates for the last 250 Myr. We demonstrate that rift-related CO2 release in the Early Cretaceous may have reached 400% of present-day rates. In first-order agreement with paleo-atmospheric CO2 concentrations from proxy

  20. Towards a transcription map spanning a 250 kb area within the DiGeorge syndrome chromosome region

    Energy Technology Data Exchange (ETDEWEB)

    Wong, W.; Emanuel, B.S.; Siegert, J. [Children`s Hospital of Philadelphia, PA (United States)] [and others

    1994-09-01

    DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) are congenital anomalies affecting predominantly the thymus, parathyroid glands, heart and craniofacial development. Detection of 22q11.2 deletions in the majority of DGS and VCFS patients implicate 22q11 haploinsufficiency in the etiology of these disorders. The VCFS/DGS critical region lies within the proximal portion of a commonly deleted 1.2 Mb region in 22q11. A 250 kb cosmid contig covering this critical region and containing D22S74 (N25) has been established. From this contig, eleven cosmids with minimal overlap were biotinylated by nick translation, and hybridized to PCR-amplified cDNAs prepared from different tissues. The use of cDNAs from a variety of tissues increases the likelihood of identifying low abundance transcripts and tissue-specific expressed sequences. A DGCR-specific cDNA sublibrary consisting of 670 cDNA clones has been constructed. To date, 49 cDNA clones from this sub-library have been identified with single copy probes and cosmids containing putative CpG islands. Based on sequence analysis, 25 of the clones contain regions of homology to several cDNAs which map within the proximal contig. LAN is a novel partial cDNA isolated from a fetal brain library probed with one of the cosmids in the proximal contig. Using LAN as a probe, we have found 19 positive clones in the DGCR-specific cDNA sub-library (4 clones from fetal brain, 14 from adult skeletal muscle and one from fetal liver). Some of the LAN-positive clones extend the partial cDNA in the 5{prime} direction and will be useful in assembling a full length transcript. This resource will be used to develop a complete transcriptional map of the critical region in order to identify candidate gene(s) involved in the etiology of DGS/VCFS and to determine the relationship between the transcriptional and physical maps of 22q11.

  1. Laboratory Evaluation of Residual Efficacy of Actellic 300 CS (Pirimiphos-Methyl and K-Othrine WG 250 (Deltamethrin on Different Indoor Surfaces

    Directory of Open Access Journals (Sweden)

    Kolade T Ibrahim

    2017-11-01

    Full Text Available The nature and type of local indoor resting wall surfaces to certain level influences the residual bio-efficacy of insecticides used in indoor residual spraying programs. Knockdown and mortality effects of an organophosphate Actellic 300 CS and pyrethroid K-Othrine WG 250 insecticides on the field-collected Culex quinquefasciatus were assessed bimonthly from July to November 2014, using World Health Organization (WHO cones bioassay test. Knockdown and mortality rates were subjected to statistical analysis using χ 2 and Student t tests. Result of the bioassay test on C quinquefasciatus showed that plywood surfaces had the best residual knockdown activity of Actellic 300 CS with knockdown rate above the WHO-recommended threshold limit of ≥95% for 30 days after treatment. This was followed by mud surface with knockdown rates ≥95% threshold limit 15 days (97% after treatment. The lowest knockdown rates of less than 95% were observed on cement surface throughout the assessment period. However, the knockdown rates of mosquitoes on deltamethrin WG 250–treated cement and plywood surfaces were 100% and ≥95%, respectively, at 30 days after treatment. But the knockdown activity was below the recommended threshold limit on mud surface during the 17 weeks trial. Knockdown activities varied significantly ( p  < .05, and it is a function of exposure periods, different surfaces, and insecticide formulations. The 24-hour mortality rates of Actellic 300 CS and K-Othrine WG 250 at 120 days after treatment were 83.6% and 86.7%, and 80% and 83.3%, on plywood and cement surfaces, respectively. A maximum residual period of 75 and 45 days were recorded for Actellic 300 CS and K-Othrine WG 250, respectively, on mud surface. Both Actellic 300 CS and K-Othrine 250 WG were highly effective against Culex mosquito. The extended residual activity of p -methyl CS compared with deltamethrin WG 250 makes it a suitable alternative insecticide against

  2. Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys.

    Science.gov (United States)

    Hruba, Lenka; McMahon, Lance R

    2017-08-01

    Synthetic cannabinoids have been prohibited due to abuse liability and toxicity. Four such synthetic cannabinoids, AM-2201 ([1-(5-fluoropentyl)indol-3-yl]-naphthalen-1-ylmethanone), CP-47,497 (2-[(1R,3S)-3-hydroxycyclohexyl]-5-(2-methyloctan-2-yl)phenol), JWH-122 [(4-methylnaphthalen-1-yl)-(1-pentylindol-3-yl)methanone], and JWH-250 [2-(2-methoxyphenyl)-1-(1-pentylindol-3-yl)ethanone], were tested for their capacity to produce CB 1 receptor-mediated discriminative stimulus effects in two groups of rhesus monkeys. One group ( n = 4) discriminated Δ 9 -tetrahydrocannabinol (∆ 9 -THC; 0.1 mg/kg i.v.), and a second group ( n = 4) discriminated the cannabinoid antagonist rimonabant (1 mg/kg i.v.) while receiving 1 mg/kg/12 hours of ∆ 9 -THC. AM-2201, JWH-122, CP-47,497, JWH-250, and ∆ 9 -THC increased ∆ 9 -THC lever responding. Duration of action was 1-2 hours for AM-2201, JWH-122, and JWH-250 and 4-5 hours for CP-47,497 and ∆ 9 -THC. Rimonabant (1 mg/kg) surmountably antagonized the discriminative stimulus effects of all cannabinoid agonists; the magnitude of rightward shift was 10.6-fold for AM-2201, 10.7-fold for JWH-122, 11.0-fold for CP-47,497, and 15.7-fold for JWH-250. The respective pK B values were not significantly different: 6.61, 6.65, 6.66, and 6.83. In ∆ 9 -THC-treated monkeys discriminating rimonabant, AM-2201 (0.1 and 0.32 mg/kg), JWH-122 (0.32 and 1 mg/kg), JWH-250 (1 and 3.2 mg/kg), and CP-47,497 (0.32, 1, and 3.2 mg/kg) produced not only rate-decreasing effects that were reversed by rimonabant, but also dose-dependent, rightward shifts in the rimonabant discrimination dose-effect function. These results show striking similarity in the CB 1 receptor mechanism mediating the subjective effects of AM-2201, JWH-122, JWH-250, and CP-47,497. For products containing AM-2201 and JWH-122, a short duration of action could lead to more frequent use; moreover, inattention to differences in potency among synthetic cannabinoids could underlie unexpected

  3. Self-affine scaling from non-integer phase-space partition in $\\pi^{+}p$ and $K^{+}p$ collisions at 250 GeV/$c$

    CERN Document Server

    Agababian, N M

    1998-01-01

    A factorial-moment analysis with real (integer and non-integer) phase space partition is applied to $\\pi^+$p and K$^+$p collisions at 250 GeV/$c$. Clear evidence is shown for self-affine rather than self-similar power-law scaling in multiparticle production. The three-dimensional self-affine second-order scaling exponent is determined to be 0.061$\\pm$0.010.

  4. Electrochemical investigations of the resistance of Inconel 600, Incoloy 800, and Type 347 stainless steel to pitting corrosion in faulted PWR secondary water at 150 to 250 C

    International Nuclear Information System (INIS)

    Hickling, J.; Wieling, N.

    1981-01-01

    Determinations of critical pitting potentials were carried out at temperatures of 150, 200, and 250 C on three corrosion resistant alloys important in the construction of nuclear steam generators. The results are assessed in terms of the effects on pitting resistance of chloride (as NaCl) and phosphate (as Na/sub 2/ HPO/sub 4/) contents of the water and test temperature. A comparison of material behavior was obtained for each set of test conditions. 18 refs

  5. Crystal structures of iron bearing tetrahedrite and tennantite at 25 and 250 degrees C by means of Rietveld refinement of synchrotron data

    DEFF Research Database (Denmark)

    Friese, K.; Grzechnik, A.; Makovicky, E.

    2008-01-01

    Rietveld refinement of X-ray synchrotron data was performed for two synthetic tetrahedrite samples, with 0.61 and 1.83 Fe atoms, and two synthetic tennantite samples with 0.10 and 1.23 Fe atoms p.f.u. M-12(Sb,As)(4)S-13. Measurements were performed at 25 and 250 degrees C. For both the phases...

  6. Transphenoidal surgery without steroid replacement in patients with morning serum cortisol below 9 μg/dl (250 Nmol/l).

    Science.gov (United States)

    De Tommasi, Claudio; Goguen, Jeannette; Cusimano, Michael D

    2012-10-01

    Adrenal insufficiency is a feared complication in patients undergoing transphenoidal surgery (TSS). Using the insulin tolerance test (ITT) for the preoperative assessment of hypothalamic-pituitary-adrenal (HPA) status is less than ideal, and the morning serum cortisol (MSC) is often used as a proxy for ITT. However, neither the ITT nor the MSC level has been validated to indicate HPA sufficiency compared to a physiological gold standard such as patients' ability to withstand transphenoidal surgery. To evaluate the intraoperative and postoperative course of nine patients with non-ACTH-secreting pituitary adenomas who did not receive intraoperative cortisol replacement despite having a preoperative MSC below 9 μg/dl (250 nmol/l) and to compare this with a set of patients with a preoperative MSC greater than 14.5 μg/dl (400 nmol/l) and another set of patients with MSC below 9 μg/dl (250 nmol/l) who received intraoperative cortisol administration. Preoperative and day 1 and day 2 postoperative MSC, intraoperative anesthetic record, vital signs, fluid balance, medications, and complications were recorded. None of the patients experienced the full syndrome of adrenal insufficiency. One patient with a preoperative MSC <9 μg/dl (250 mol/l) had isolated postoperative fatigue and required cortisol replacement. No patient suffered any life-threatening complications. There were no differences among the three groups in their intraoperative or postoperative courses when compared for intraoperative hypotension, acute blood pressure drop, and administration of vasopressors. This study suggests that TSS can be performed safely in patients with preoperative MSC less than 9 μg/dl (250 nmol/l) in closely monitored settings without intraoperative cortisol administration. Further studies are warranted.

  7. Neutron- and proton-induced nuclear data evaluation of thorium, uranium and curium isotopes for energies up to 250 MeV

    International Nuclear Information System (INIS)

    Lee, Young-Ouk; Chang, Jonghwa; Fukahori, Tokio; Konobeyev, A.Yu.

    2004-01-01

    The evaluation of neutron and proton nuclear data for thorium-232, U-233,234,236, and Cm-243,244,245,246 isotopes have been performed at energies up to 250 MeV. Neutron data was evaluated at energies from 20 MeV to 250 MeV, and combined with the JENDL-3.3 data at 20 MeV, while proton data was obtained for energies from 1 to 250 MeV. Nuclear model parameters are largely based on the IAEA-RIPL recommendation, and adjusted to better reproduce the available measurements. The coupled channel optical model was applied to calculate the total, reaction, elastic, and direct inelastic cross sections, and to obtain the transmission coefficients. Decay of excited nuclei was described with the Hauser-Feshbach and exciton models using the GNASH code to simultaneously handle neutron, proton, deuteron, triton, helium-3, α, γ emission and fissions. Special attention was paid to the fission cross sections for energies where experimental data are scant, using appropriate systematics and fittings. Particles and γ emission spectra after fission were calculated based on the statistical approach of Fong, and adjusted to the experimental data using the ALICE-ASH code. (author)

  8. Developing a 30-m grassland productivity estimation map for central Nebraska using 250-m MODIS and 30-m Landsat-8 observations

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.

    2015-01-01

    Accurately estimating aboveground vegetation biomass productivity is essential for local ecosystem assessment and best land management practice. Satellite-derived growing season time-integrated Normalized Difference Vegetation Index (GSN) has been used as a proxy for vegetation biomass productivity. A 250-m grassland biomass productivity map for the Greater Platte River Basin had been developed based on the relationship between Moderate Resolution Imaging Spectroradiometer (MODIS) GSN and Soil Survey Geographic (SSURGO) annual grassland productivity. However, the 250-m MODIS grassland biomass productivity map does not capture detailed ecological features (or patterns) and may result in only generalized estimation of the regional total productivity. Developing a high or moderate spatial resolution (e.g., 30-m) productivity map to better understand the regional detailed vegetation condition and ecosystem services is preferred. The 30-m Landsat data provide spatial detail for characterizing human-scale processes and have been successfully used for land cover and land change studies. The main goal of this study is to develop a 30-m grassland biomass productivity estimation map for central Nebraska, leveraging 250-m MODIS GSN and 30-m Landsat data. A rule-based piecewise regression GSN model based on MODIS and Landsat (r = 0.91) was developed, and a 30-m MODIS equivalent GSN map was generated. Finally, a 30-m grassland biomass productivity estimation map, which provides spatially detailed ecological features and conditions for central Nebraska, was produced. The resulting 30-m grassland productivity map was generally supported by the SSURGO biomass production map and will be useful for regional ecosystem study and local land management practices.

  9. The effect of vaccination with the PAV-250 strain classical swine fever (CSF) virus on the airborne transmission of CSF virus.

    Science.gov (United States)

    Gonzalez, C; Pijoan, C; Ciprian, A; Correa, P; Mendoza, S

    2001-09-01

    The airborne transmission of Classical Swine Fever (CSF) virus to susceptible pigs, as well as the effect of vaccination with the CSF virus PAV-250 strain was investigated on this mode of transmission. Experiment I: four pigs were inoculated with the ALD CSFV strain (10(4.3) 50% TCID) by the intramuscular route, and at the onset of fever, they were introduced into an enclosed chamber. At the end of the experiment surviving pigs were sedated, anesthetized and euthanatized. Experiment II: four pigs were previously vaccinated with the CSF virus PAV-250 strain, and at 14 days post-vaccination they were challenged with the CSF virus ALD strain. In both experiments, four susceptible pigs were exposed to infectious aerosols by placing them in a chamber connected by a duct to the adjacent pen containing the infected animals and were kept there for 86 hs. In Experiment I, pigs exposed to contaminated air died as a result of infection with CSF virus on days 14, 21 and 28 post-inhalation. These four pigs seroconverted from day 12 post-inhalation. CSF virus was isolated from these animals, and the fluorescent antibody test on tonsils was positive. In Experiment II, a vaccinated pig exposed to contaminated air did not seroconvert, nor was CSF virus isolated from lymphoid tissues. However, mild fluorescence in tonsil sections from these pigs was observed. In conclusion, CSF virus was shown to be transmitted by air at a distance of 1 m to susceptible pigs. Vaccination with the PAV-250 CSF virus strain protected the pigs from clinical disease under the same conditions.

  10. Asymmetries from the 4He(p,2p)3H reaction at 250 and 500 MeV using polarized protons

    International Nuclear Information System (INIS)

    Margaziotis, D.J.; Epstein, M.B.; van Oers, W.T.H.; Hasell, D.K.; Abegg, R.; Moss, G.A.; Greeniaus, L.G.; Cameron, J.M.; Stetz, A.W.

    1982-01-01

    Analyzing powers for the 4 He(p,2p) 3 H reaction have been measured at 250 and 500 MeV for three pairs of quasifree angles, i.e., 55 0 -25 0 , 50 0 -30 0 , and 45 0 -35 0 . The range of recoil momenta covered is from zero to 150 MeV/c. The data have been compared with distorted-wave impulse approximation predictions. In general only reasonable agreement is obtained, pointing to deficiencies in the distorted wave impulse approximation even at low recoil momenta

  11. A cross section measurement of charm hyperons Ξc+ and Ξc0 in 250 GeV p/K/π-nucleon interactions

    International Nuclear Information System (INIS)

    Francisco, J.; Vergara, A.

    1995-01-01

    Fermilab Experiment 769 used a charge-selected, hadron beam of mean energy 250 GeV/c, composed of pions, kaons, and protons, impinging on beryllium, aluminum, copper and tungsten targets. Using a sample of approximately 4000 Ξ s - → Λ 0 π - decays, measurements of the charm baryon forward cross sections times branching ratio π ± N → Ξ c + X and π ± N → Ξ c 0 X are presented. Upper limits on α x BR are also determined for the states Ξ c + → Ξ s - π + π + and Ξ c 0 → Ξ s - π + produced in (p, π + , π - , K + , K - )-nucleon interactions

  12. Atomic Mass Dependence of $\\Xi^{-}$ Baryon and $\\bar \\Xi^+$ Baryon Production in Central 250-GeV/c $\\pi^-$ - Nucleon Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Dagenhart, William David [Tufts U.

    2000-02-01

    We present the first measurement of the atomic mass dependence of central $\\Xi^-$ and $\\overline{\\Xi}^+$ production. It is measured using a sample of 22,459 $\\Xi^-$'s and $\\overline{\\Xi}^+$'s produced in collisions between a 250 GeV/c $\\pi^-$ beam and targets of beryllium, aluminum, copper, and tungsten. The relative cross sections are fit to the two parameter function $\\sigma_0 A^{\\alpha}$, where A is the atomic mass. We measure $\\alpha$ = 0:924 $\\pm$ 0:020 $\\pm$ 0:025, for Feynman-x in the range $\\pm$ 0:09 < $x_F$ < 0:15.

  13. SETUP FOR MEASUREMENT OF THE PHOTOMETRIC, RADIOMETRIC, SPECTRAL AND SPATIAL CHARACTERISTICS OF RADIATION OF LASER DIODES AND LEDS IN THE SPECTRAL RANGE FROM 250 TO 900 NM

    Directory of Open Access Journals (Sweden)

    S. V. Nikanenka

    2015-01-01

    Full Text Available Information about principle of operation of the setup for measurement of the photometric, radiometric, spectral and spatial characteristics of radiation of laser diodes and LEDs in the spectral range from 250 to 900 nm constructed in the B.I. Stepanov Institute of Physics of NAS of Belarus and the results of its metrological certification are presented. New approaches to measure the averaged value of the luminance and spectral radiance LEDs and laser diodes, the spatial distribution of luminous intensity and power density of laser diodes radiation, the luminous intensity and radiant intensity LEDs and laser diodes. 

  14. Guideline concerning financial aid by the state to '250 MW wind' wind power plants within the framework of the third programme 'Energy research and energy technologies'

    International Nuclear Information System (INIS)

    1994-01-01

    An industrial-scale wind power experiment will receive financial aid for several years. An installed power of 250 MW is to be reached within a 5-year period if possible. The BMFT will grant financial aid on a per kWh basis up to a maximum sum, or - if desired by certain applicants - in the form of an investment aid, both for a maximum period of 10 years from the start-up of the wind power plant. The BMFT will also finance a scientific programme for measurement and evaluation. (orig.) [de

  15. Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity.

    Science.gov (United States)

    Thibault, Thomas; Degrouard, Jeril; Baril, Patrick; Pichon, Chantal; Midoux, Patrick; Malinge, Jean-Marc

    2017-03-17

    Double-stranded DNA minicircles of less than 1000 bp in length have great interest in both fundamental research and therapeutic applications. Although minicircles have shown promising activity in gene therapy thanks to their good biostability and better intracellular trafficking, minicircles down to 250 bp in size have not yet been investigated from the test tube to the cell for lack of an efficient production method. Herein, we report a novel versatile plasmid-free method for the production of DNA minicircles comprising fewer than 250 bp. We designed a linear nicked DNA double-stranded oligonucleotide blunt-ended substrate for efficient minicircle production in a ligase-mediated and bending protein-assisted circularization reaction at high DNA concentration of 2 μM. This one pot multi-step reaction based-method yields hundreds of micrograms of minicircle with sequences of any base composition and position and containing or not a variety of site-specifically chemical modifications or physiological supercoiling. Biochemical and cellular studies were then conducted to design a 95 bp minicircle capable of binding in vitro two NF-κB transcription factors per minicircle and to efficiently inhibiting NF-κB-dependent transcriptional activity in human cells. Therefore, our production method could pave the way for the design of minicircles as new decoy nucleic acids. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. Stream-sediment samples reanalyzed for major, rare earth, and trace elements from seven 1:250,000-scale quadrangles, south-central Alaska, 2007-09

    Science.gov (United States)

    Gamble, Bruce M.; Bailey, Elizabeth A.; Shew, Nora B.; Labay, Keith A.; Schmidt, Jeanine M.; O'Leary, Richard M.; Detra, David E.

    2010-01-01

    During the 1960s through the 1980s, the U.S. Geological Survey conducted reconnaissance geochemical surveys of drainage basins throughout most of the Iliamna, Lake Clark, Lime Hills, and Talkeetna 1:250,000-scale quadrangles and parts of the McGrath, Seldovia, and Tyonek 1:250,000-scale quadrangles in Alaska. These geochemical surveys provide data necessary to assess the potential for undiscovered mineral resources and provide data that may be used to determine regional-scale element baselines. This report provides new data for 1,075 of the previously collected stream-sediment samples. The new analyses include a broader spectrum of elements and provide data that are more precise than the original analyses. All samples were analyzed for arsenic by hydride generation atomic absorption spectrometry, for gold, palladium, and platinum by inductively coupled plasma-mass spectrometry after lead button fire assay separation, and for a suite of 55 major, rare earth, and trace elements by inductively coupled plasma-atomic emission spectrometry and inductively coupled plasma-mass spectrometry after sodium peroxide sinter at 450 degrees Celsius.

  17. Buckling measurements up to 250 deg C on lattices of Agesta clusters and on D{sub 2}O alone in the pressurized exponential assembly TZ

    Energy Technology Data Exchange (ETDEWEB)

    Persson, R.; Andersson, A.J.W.; Wikdahl, C.E.

    1966-11-15

    Buckling determinations by means of flux mapping were performed in TZ up to 250 deg C on two lattices of Aagesta fuel assemblies in D{sub 2}O and on D{sub 2}O alone. Most of the flux measurements were made with fission counters in pressure thimbles. The perturbations caused by the thimbles were studied experimentally in various ways and compared with two group diffusion-theory calculations. In one of the lattices the effectiveness of a control rod (AglnCd) was also investigated. The results of the diffusion length experiments indicated some systematic error of the order of 0.15 - 0.10/m{sup 2} in the bucklings measured, though the temperature dependence should be well established. The bucklings of the two lattices studied (square pitches 24 and 27 cm) were found to be less sensitive to temperature than theoretical calculations predict, the temperature coefficient being more than 10 per cent smaller. The buckling changes from 20 to 250 deg C were about -2.4 and -1.8/m{sup 2}, respectively, for the two lattices. During part of the experimental period we had, for some unexplained reason, about 30 per cent excess absorption in the heavy water.

  18. Low cycle fatigue behaviour of neutron irradiated copper alloys at 250 and 350 deg. C. (ITER R and D Task no. T213)

    International Nuclear Information System (INIS)

    Singh, B.N.; Stubbins, J.F.; Toft, P.

    2000-03-01

    The fatigue behaviour of a dispersion strengthened and a precipitation hardened copper alloys was investigated with and without irradiation exposure. Fatigue specimens of these alloys were irradiated with fission neutrons in the DR-3 reactor at Risoe with a flux of ∼2.5 x 10 17 n/m 2 s (E> 1 MeV) to influence levels of 1.0 - 1.5 x 10 24 n/m 2 (E> 1 MeV) at 250 and 350 deg. C. These irradiations were carried out in temperature controlled rigs where the irradiation temperature was monitored and controlled continuously throughout the whole irradiation experiment. Both unirradiated and irradiated specimens were fatigue tested in vacuum at the irradiation temperatures of 250 and 350 deg. C in a strain controlled mode with a loading frequency of 0.5Hz. Post-fatigue microstructures were examined using transmission electron microscopy and the fracture surfaces were investigated using scanning electron microscope. The present investigations demonstrated that the fatigue life decreases with increasing temperature and that the exposure to neutron irradiation causes further degradation in fatigue life at both temperatures. These results are discussed in terms of the observed post-fatigue microstructures and the fracture surface morphology. Finally, the main conclusions and their implications are summarised. (au)

  19. Buckling measurements up to 250 deg C on lattices of Agesta clusters and on D2O alone in the pressurized exponential assembly TZ

    International Nuclear Information System (INIS)

    Persson, R.; Andersson, A.J.W.; Wikdahl, C.E.

    1966-11-01

    Buckling determinations by means of flux mapping were performed in TZ up to 250 deg C on two lattices of Aagesta fuel assemblies in D 2 O and on D 2 O alone. Most of the flux measurements were made with fission counters in pressure thimbles. The perturbations caused by the thimbles were studied experimentally in various ways and compared with two group diffusion-theory calculations. In one of the lattices the effectiveness of a control rod (AglnCd) was also investigated. The results of the diffusion length experiments indicated some systematic error of the order of 0.15 - 0.10/m 2 in the bucklings measured, though the temperature dependence should be well established. The bucklings of the two lattices studied (square pitches 24 and 27 cm) were found to be less sensitive to temperature than theoretical calculations predict, the temperature coefficient being more than 10 per cent smaller. The buckling changes from 20 to 250 deg C were about -2.4 and -1.8/m 2 , respectively, for the two lattices. During part of the experimental period we had, for some unexplained reason, about 30 per cent excess absorption in the heavy water

  20. Matrimid-JUC-62 and Matrimid-PCN-250 mixed matrix membranes displaying light-responsive gas separation and beneficial ageing characteristics for CO2/N2 separation.

    Science.gov (United States)

    Prasetya, Nicholaus; Teck, Anastasia A; Ladewig, Bradley P

    2018-02-13

    The performance of two generation-3 light-responsive metal-organic framework (MOF), namely JUC-62 and PCN-250, was investigated in a mixed matrix membrane (MMM) form. Both of them were incorporated inside the matrimid as the polymer matrix. Using our custom-designed membrane testing cell, it was observed that the MMMs showed up to 9% difference in CO 2 permeability between its pristine and UV-irradiated condition. This shows that the light-responsive ability of the light-responsive MOFs could still be maintained. Thus, this finding is applicable in designing a smart material. Apart from that, the MMMs also has the potential to be applied for post-combustion carbon capture. At loadings up to 15 wt%, both CO 2 permeability and CO 2 /N 2 ideal selectivity could be significantly improved and surpassed the value exhibited by most of the MOF-matrimid MMM. Lastly the long term performance of the MMM was also evaluated and it was observed that both MMM could maintain their performance up to 1 month with only a slight decrease in CO 2 permeability observed for 10 wt% PCN-250-matrimid. This study then opens up the possibility to fabricate a novel anti-aging multifunctional membrane material that is applicable as a smart material and also in post combustion carbon capture applications.

  1. Magnetoresistance properties of Fe0,2C0,8 composite materials pre and post gamma irradiated at 250 kGy dose

    International Nuclear Information System (INIS)

    Yunasfi; Setyo Purwanto; Wisnu A A

    2009-01-01

    Research about change of, magnetoresistance properties of Fe 0,2 C 0,8 composite materials pre and post gamma irradiation at a dose of 250 kGy was carried out. Fe 0,2 C 0,8 was prepared by mixing of Fe and C powder with the ratio of Fe : C set on 20:80 in weight %. In this research, the phase structure and magnetic properties of Fe 0,2 C 0,8 composite materials after 250 KGy dose of gamma irradiation have been measured and analyzed. The phase structure of Fe 0,2 C 0,8 was analyzed using X-ray diffractometer (XRD), whole the magnetoresistance properties was characterized using Four Point Probe method. The analyzing results showed the decreasing of X-ray diffraction peak intensity, but also in the same time showed the increasing of magnetoresistance properties after gamma irradiation. The enhancement of magnetoresistance value reached 5 times at 7,5 kOe magnetic field. This enhancement was caused due to structure defect within Fe 0,2 C 0,8 composite initiated by interaction between radiation of gamma ray and composite materials that further causes a change of magnetic interaction intensity in this materials. (author)

  2. Thermal power calibration of the TRIGA Mark I IPR-R1 reactor during the upgrading tests to 250 kW

    International Nuclear Information System (INIS)

    Mesquita, Amir Zacarias; Maretti, Fausto Junior; Rezende, Hugo Cesar

    2002-01-01

    This paper presents the results and the methodology used to calibrate the thermal power of the TRIGA MARK I IPR-R1 Reactor in CDTN, Belo Horizonte, Brazil. This calibration was realized during the operation tests carried out to allow the reactor power upgrade from the current 100 kW to 250 kW. The methodology consisted in the measurement of the inlet and outlet temperature and the water flow in the primary cooling loop. The thermal balance together with the thermal losses gave the thermal power. There were made three sequences of tests. The first rising of the thermal power was made with the usual configuration of the core (59 fuel elements). After the changing of the ion chambers position and the control rod and the increase of the number of fuels (63 fuel elements), a new evaluation of the thermal power was accomplished, having been obtained a thermal power of 234 kW, for an indication of 250 kW in the lineal channel. After the return of the core to the initial configuration (59 fuel elements), it took place a new test, getting back the reactor to the power level of 100 kW. (author)

  3. Integrating a 250 mL-spinner flask with other stirred bench-scale cell culture devices: a mass transfer perspective.

    Science.gov (United States)

    Vallejos, Jose R; Brorson, Kurt A; Moreira, Antonio R; Rao, Govind

    2011-01-01

    The bioprocess development cycle is a complex task that requires a complete understanding of the engineering of the process (e.g., mass transfer, mixing, CO(2) removal, process monitoring, and control) and its affect on cell biology and product quality. Despite their widespread use in bioprocess development, spinner flasks generally lack engineering characterization of critical physical parameters such as k(L)a, P/V, or mixing time. In this study, mass transfer characterization of a 250-mL spinner flask using optical patch-based sensors is presented. The results quantitatively show the effect of the impeller type, liquid filling volume, and agitation speed on the volumetric mass transfer coefficient (k(L)a) in a 250-mL spinner flask, and how they can be manipulated to match mass transfer capability at large culture devices. Thus, process understanding in spinner flasks can be improved, and these devices can be seamlessly integrated in a rational scale-up strategy from cell thawing to bench-scale bioreactors (and beyond) in biomanufacturing. Copyright © 2011 American Institute of Chemical Engineers (AIChE).

  4. Effect of chloride and sulphate ions on the electrochemical corrosion behavior of alloy 800NG in PWR secondary water environment at 250 deg C

    International Nuclear Information System (INIS)

    Mansur, Fabio A.; Schvartzman, Monica Maria de A.M.; Quinan, Marco A.D.; Soares, Antonio E.G.; Nogueira, Pedro Henrique B.O.

    2013-01-01

    Alloy 800NG (nuclear grade) is used in nuclear steam generators (SG) as the tubing material for pressurized water reactors (PWRs) because of its high corrosion resistance. The corrosion resistance is due to the protective character of the oxide film formed on the tube surface by contact with the high temperature pressurized water. Nevertheless, corrosion has been the major cause of tube failures in nuclear SGs. The existing experience of different nuclear power plants shows that the water chemistry has an important role in maintaining the integrity of the protective oxide films. Many of such problems have been attributed to secondary side water chemistry conditions and excursions, many of which have been resulted from condenser cooling water ingress. Alloy 800 is known to undergo passivity breakdown and pitting in the presence of chloride ions under oxidative water conditions. In this work the effect of chloride and sulphate ions at various concentrations on the corrosion behavior of Alloy 800 tube at 250 deg C was investigated using the potentiodynamic anodic polarization technique. An active-passive transition occurred at 250 deg C in all studied conditions and the oxide film grown on surface showed greater porosity and lower resistance to localised corrosion in all studied conditions. (author)

  5. Granulocyte-specific monoclonal antibody technetium-99m-BW 250/183 and indium-111 oxine-labelled leucocyte scintigraphy in inflammatory bowel disease.

    Science.gov (United States)

    Segarra, I; Roca, M; Baliellas, C; Vilar, L; Ricart, Y; Mora, J; Puchal, R; Martin-Comin, J

    1991-01-01

    Thirty-three patients suspected of suffering from inflammatory bowel disease were studied. Autologous leucocytes were labelled with indium 111 oxine and re-injected simultaneously with 0.3-0.5 mg of technetium 99m granulocyte-specific monoclonal antibody BW 250/183. Two scans were obtained, the early scan 3-4 h postinjection (p.i.) and the late scan 18-24 h p.i. Using the endoscopy study as standard, the diagnostic accuracy of both agents was determined. Sensitivity, specificity and accuracy of 111In scans was 88.8%, 100.0% and 93.7% at 4 h and 94.7%, 100.0% and 96.9% at 24 h, respectively. Concerning the results using antibodies, the values were 61.1%, 100.0% and 78.1% at 4 h and 78.9%, 92.8% and 84.8% at 24 h, respectively. Segmental analysis showed concordance in 89.3% and 93.3% of the cases at 4 and 24 h, respectively. Though less sensitive and less accurate than scanning employing indium 111 leucocytes, BW 250/183 granulocyte-specific scintigraphy can be used for inflammatory bowel disease diagnosis and localization.

  6. Granulocyte-specific monoclonal antibody technetium-99m-BW 250/183 and indium-111 oxine-labelled leukocyte scintigraphy in inflammatory bowel disease

    Energy Technology Data Exchange (ETDEWEB)

    Segarra, I.; Roca, M.; Ricart, Y.; Mora, J.; Puchal, R.; Martin-Comin, J. (Hospital de Bella Vista, Barcelona (Spain). Servicio de Medicina Nuclear); Baliellas, C.; Vilar, L. (Hospital de Bella Vista, Barcelona (Spain). Servicio de Gastroenterologia)

    1991-09-01

    Thirty-three patients suspected of suffering from inflammatory bowel disease were studied. Autologous leukocytes were labelled with indium 111 oxine and re-injected simultaneously with 0.3-0.5 mg of {sup 99m}Tc-labelled granulocyte-specific monoclonal antibody BW 250/183. Two scans were obtained, the early scan 3-4 h post-injection (p.i.) and the late scan 18-24 h p.i. Using the endoscopy study as standard, the diagnostic accuracy of both agents was determined. Sensitivity, specificity and accuracy of {sup 111}In-scans was 88.8%, 100.0% and 93.7% at 4 h and 94.7%, 100.0% and 96.9% and 24 h, respectively. Concerning the results using antibodies, the values were 61.1%, 100.0% and 78.1% at 4 h and 78.9%, 92.8% and 84.8% at 24 h, respectively. Segmental analysis showed concordance in 89.3% and 93.3% of the cases at 4 and 24 h, respectively. Though less sensitive and less accurate than scanning employing indium 111 leukocytes, the BW 250/183 granulocyte-specific scintigraphy can be used for inflammatory bowel disease diagnosis and localization. (orig.).

  7. Secondary neutron spectrum from 250-MeV passively scattered proton therapy: measurement with an extended-range Bonner sphere system.

    Science.gov (United States)

    Howell, Rebecca M; Burgett, E A

    2014-09-01

    Secondary neutrons are an unavoidable consequence of proton therapy. While the neutron dose is low compared to the primary proton dose, its presence and contribution to the patient dose is nonetheless important. The most detailed information on neutrons includes an evaluation of the neutron spectrum. However, the vast majority of the literature that has reported secondary neutron spectra in proton therapy is based on computational methods rather than measurements. This is largely due to the inherent limitations in the majority of neutron detectors, which are either not suitable for spectral measurements or have limited response at energies greater than 20 MeV. Therefore, the primary objective of the present study was to measure a secondary neutron spectrum from a proton therapy beam using a spectrometer that is sensitive to neutron energies over the entire neutron energy spectrum. The authors measured the secondary neutron spectrum from a 250-MeV passively scattered proton beam in air at a distance of 100 cm laterally from isocenter using an extended-range Bonner sphere (ERBS) measurement system. Ambient dose equivalent H*(10) was calculated using measured fluence and fluence-to-ambient dose equivalent conversion coefficients. The neutron fluence spectrum had a high-energy direct neutron peak, an evaporation peak, a thermal peak, and an intermediate energy continuum between the thermal and evaporation peaks. The H*(10) was dominated by the neutrons in the evaporation peak because of both their high abundance and the large quality conversion coefficients in that energy interval. The H*(10) 100 cm laterally from isocenter was 1.6 mSv per proton Gy (to isocenter). Approximately 35% of the dose equivalent was from neutrons with energies ≥20 MeV. The authors measured a neutron spectrum for external neutrons generated by a 250-MeV proton beam using an ERBS measurement system that was sensitive to neutrons over the entire energy range being measured, i.e., thermal to

  8. Age-related alterations in skeletal metabolism--24-hr whole-body retention of diphosphonate in 250 normal subjects: concise communication

    International Nuclear Information System (INIS)

    Fogelman, I.; Bessent, R.

    1982-01-01

    Twenty-four-hour measurements of whole-body retention (WBR) of 99 mTc diphosphonate (a sensitive measure of skeletal metabolism) have been obtained in 250 healthy volunteer subjects. WBR values were found to fall from the age of 20 yr until 35 yr and then in men to rise linearly thereafter. Women showed a similar pattern initially but there was a marked rise in WBR corresponding to the menopausal years. Our results lend support to the belief that skeletal metabolism increases with age. It is suggested that some imbalance must always exist between resorption and formation in bone, with net loss of bone mineral, and increasing levels of skeletal metabolism will exaggerate this imbalance and accelerate the rate of bone loss

  9. Bioequivalence evaluation of two brands of amoxicillin/clavulanic acid 250/125 mg combination tablets in healthy human volunteers: use of replicate design approach.

    Science.gov (United States)

    Idkaidek, Nasir M; Al-Ghazawi, Ahmad; Najib, Naji M

    2004-12-01

    The purpose of this study was to apply a replicate design approach to a bioequivalence study of amoxicillin/clavulanic acid combination following a 250/125 mg oral dose to 23 subjects, and to compare the analysis of individual bioequivalence with average bioequivalence. This was conducted as a 2-treatment 2-sequence 4-period crossover study. Average bioequivalence was shown, while the results from the individual bioequivalence approach had no success in showing bioequivalence. In conclusion, the individual bioequivalence approach is a strong statistical tool to test for intra-subject variances and also subject-by-formulation interaction variance compared with the average bioequivalence approach. copyright (c) 2004 John Wiley & Sons, Ltd.

  10. Measurement of the Production Cross Section for the Charmed Baryon $\\Lambda_c$ in 250 GeV/c Pion-Nucleon Interactions

    Energy Technology Data Exchange (ETDEWEB)

    dos Reis, Alberto Correa [Rio de Janeiro, CBPF

    1992-04-01

    This work a presents a measurement of the total cross section for the charmed baryon $\\Lambda_c$ times the branching fraction of the mode $\\Lambda_c \\to pK\\bar{\\mu}$, for the kinematical region $x_F$ > O in $\\pi$-nucleus interactions at 250 GeV/c. This measurement is made with data from the experiment E769, collected during 1987/1988 at the FERMILAB Tagged Photon Laboratory. A segmented target of berillium, aluminum, copper and tungsten was used. Based on the A dependence measurement, made by E769, and on the available branching fractions, the total cross section per nucleon is calculated. The result is compared with other experiments and with some theoretical predictions inspired on QCD.

  11. European Collaboration for High-Resolution Measurements of Neutron Cross Sections between 1 MeV and 250 MeV

    CERN Multimedia

    Leal, L C; Kitis, G; Guber, K H; Yuasa nakagawa, K; Koehler, P E; Quaranta, A

    2002-01-01

    The experimental determination of neutron cross section data has always been of primary importance in Nuclear Physics. Many of the salient features of nuclear levels and densities can be determined from the resonant structure of such cross sections and of their decay scheme. An associated importance of precise neutron induced reaction cross sections has resulted from the worldwide interest in Accelerator Driven Systems (ADS) that has emerged at CERN and elsewhere. Many applications, such as accelerator-based transmutation of nuclear waste, energy amplification medical research, astrophysical applications and also fusion research require nuclear data that quantitatively and qualitatively go beyond the presently available traditional evaluation.\\\\ \\\\We consider a spallation driven TOF facility at the CERN-PS with an unprecedented neutron flux (1000 times the existing ones) in the broad energy range between 1 eV and 250 MeV and with very high energy resolution. The present concept for an intense neutron source m...

  12. Discovery of abundant cellulose microfibers encased in 250 Ma Permian halite: a macromolecular target in the search for life on other planets.

    Science.gov (United States)

    Griffith, Jack D; Willcox, Smaranda; Powers, Dennis W; Nelson, Roger; Baxter, Bonnie K

    2008-04-01

    In this study, we utilized transmission electron microscopy to examine the contents of fluid inclusions in halite (NaCl) and solid halite crystals collected 650 m below the surface from the Late Permian Salado Formation in southeastern New Mexico (USA). The halite has been isolated from contaminating groundwater since deposition approximately 250 Ma ago. We show that abundant cellulose microfibers are present in the halite and appear remarkably intact. The cellulose is in the form of 5 nm microfibers as well as composite ropes and mats, and was identified by resistance to 0.5 N NaOH treatment and susceptibility to cellulase enzyme treatment. These cellulose microfibers represent the oldest native biological macromolecules to have been directly isolated, examined biochemically, and visualized (without growth or replication) to date. This discovery points to cellulose as an ideal macromolecular target in the search for life on other planets in our Solar System.

  13. Diseño y desarrollo de un chasis de una motocicleta de 250cc para la “II Competición Internacional MotoStudent”

    OpenAIRE

    García García, Ismael

    2013-01-01

    [SP]El objeto de este proyecto es el diseño y cálculo estructural del chasis de una motocicleta de competición, así como su desarrollo y posterior fabricación. Concretamente se trata de una motocicleta de 250 c.c. y 4 Tiempos, que posteriormente participará en el circuito de Motorland (Aragón) en la “II Competición Internacional MotoStudent”. Por tanto, el objetivo será encontrar el diseño más óptimo de chasis que permita obtener una motocicleta lo más competitiva posible. S...

  14. A Dependence Study of $\\Xi^{*0}$ and $\\bar{\\Xi}^{*0}$ in 250 GeV/c $\\pi^-$. $K^-$ -nucleon Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Seixas de Rezende, Fabio Antonio; /Rio de Janeiro, CBPF

    2005-04-01

    A direct measurement of the mass number (A) dependence of the production of the hyperon {Xi}*{sup 0} and its opposite {bar {Xi}}*{sup 0} in {pi}{sup -}, K{sup -} beam-nucleon interactions at 250 GeV/c is reported. The data derive from the experiment E769 at Fermilab. The results were obtained for different targets: Be, Al, Cu and W. It was observed the data are found to be well described by the parametrization {sigma}{sub A} = {sigma}{sub 0}A{sup {alpha}}, {alpha} being calculated for different beams. The results obtained are compared with those results of E769 experiment. The results shown here are preliminary.

  15. Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells

    International Nuclear Information System (INIS)

    Amara, Salem; Douki, Thery; Ravanat, Jean-Luc; Garrel, Catherine; Guiraud, Pascale; Favier, Alain; Sakly, Mohsen; Rhouma, Khemais Ben; Abdelmelek, Hafedh

    2007-01-01

    The aim of this study was to investigate the effect of static magnetic field (SMF) exposure in antioxidant enzyme activity, the labile zinc fraction and DNA damage in THP1 cells (monocyte line). Cell culture flasks were exposed to SMF (250 mT) during 1 h (group 1), 2 h (group 2) and 3 h (group 3). Our results showed that cell viability was slightly lower in SMF-exposed groups compared to a sham exposed group. However, SMF exposure failed to alter malondialdehyde (MDA) concentration (+6%, p > 0.05) and glutathione peroxidase (GPx) (-5%, p > 0.05), catalase (CAT) (-6%, p > 0.05) and superoxide dismutase (SOD) activities (+38%, p > 0.05) in group 3 compared to the sham exposed group. DNA analysis by single cell gel electrophoresis (comet assay) revealed that SMF exposure did not exert any DNA damage in groups 1 and 2. However, it induced a low level of DNA single strand breaks in cells of group 3. To further explore the oxidative DNA damage, cellular DNA for group 3 was isolated, hydrolyzed and analysed by HPLC-EC. The level of 8-oxodGuo in this group remained unchanged compared to the sham exposed group (+6.5%, p > 0.05). Cells stained with zinc-specific fluorescent probes zinpyr-1 showed a decrease of labile zinc fraction in all groups exposed to SMF. Our data showed that SMF exposure (250 mT, during 3 h) did not cause oxidative stress and DNA damage in THP1 cells. However, SMF could alter the intracellular labile zinc fraction

  16. Ovarian cancers arising from endometriosis: a microenvironmental biomarker study including ER, HNF1ß, p53, PTEN, BAF250a, and COX-2.

    Science.gov (United States)

    Lai, Chiung-Ru; Hsu, Chih-Yi; Chen, Yi-Jen; Yen, Ming-Shyen; Chao, Kuan-Chong; Li, Anna Fen-Yau

    2013-11-01

    The microenvironmental biomarkers of different subtypes of ovarian cancers arising from endometriosis have not been studied in Taiwan. Their expression can help in understanding the carcinogenic mechanism. Our study used immunohistochemistry to compare the expression of estrogen receptor (ER), hepatocyte nuclear factor-1 beta (HNF1ß), p53, phosphatase and tensin homolog (PTEN), BAF250a, and cyclooxygenase-2 (COX-2) among 79 cases of endometriosis-associated ovarian cancers, including 40 (50%) clear cell carcinomas (CCCs), 33 (41%) endometrioid (EM) adenocarcinomas, four (5%) serous carcinomas, one adenosquamous carcinoma, and one adenosarcoma. Positive stainings for ER, HNF1ß, p53, and COX-2 were identified in 34 (43%), 30 (38%), 10 (13%), and 44 (56%) cases. Loss of PTEN and BAF250a were noted in 29 (37%) and 37 (47%) cases. The expression of ER was reversely correlated with that of HNF1ß (rho = -0.417, p p53 (rho = 0.284, p = 0.011). ER positivity was commonly identified in EM adenocarcinomas (91%), and rarely in CCCs (8%) and serous carcinoma (0%; p carcinomas (50%), but less in EM adenocarcinoma (6%; p p53, COX-2, and PTEN, there was no difference between the invasive and precursor parts. Our results supported the suggestion that estrogen-dependent ovarian cancer arising from endometriosis is substantially more associated with EM adenocarcinoma than CCCs. The positive HNF1ß staining was a frequent finding in CCCs, but not in EM adenocarcinoma. The similar staining patterns of atypical endometriosis glandular cells with the invasive parts confirmed their precursor status. Copyright © 2013. Published by Elsevier B.V.

  17. Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells

    Energy Technology Data Exchange (ETDEWEB)

    Amara, Salem [Laboratoire de Physiologie Animale, Faculte des Sciences de Bizerte, 7021 Jarzouna (Tunisia); Douki, Thery [Commissariat d' Energie Atomique DRFMC/SCIB, Laboratoire des Lesions des Acides Nucleiques, Grenoble (France); Ravanat, Jean-Luc [Commissariat d' Energie Atomique DRFMC/SCIB, Laboratoire des Lesions des Acides Nucleiques, Grenoble (France); Garrel, Catherine [Laboratoire de Stress Oxydant, Departement de Biologie Integree, CHU- Grenoble (France); Guiraud, Pascale [Laboratoire de Stress Oxydant, Departement de Biologie Integree, CHU- Grenoble (France); Favier, Alain [Laboratoire de Stress Oxydant, Departement de Biologie Integree, CHU- Grenoble (France); Sakly, Mohsen [Laboratoire de Physiologie Animale, Faculte des Sciences de Bizerte, 7021 Jarzouna (Tunisia); Rhouma, Khemais Ben [Laboratoire de Physiologie Animale, Faculte des Sciences de Bizerte, 7021 Jarzouna (Tunisia); Abdelmelek, Hafedh [Laboratoire de Physiologie Animale, Faculte des Sciences de Bizerte, 7021 Jarzouna (Tunisia)

    2007-02-21

    The aim of this study was to investigate the effect of static magnetic field (SMF) exposure in antioxidant enzyme activity, the labile zinc fraction and DNA damage in THP1 cells (monocyte line). Cell culture flasks were exposed to SMF (250 mT) during 1 h (group 1), 2 h (group 2) and 3 h (group 3). Our results showed that cell viability was slightly lower in SMF-exposed groups compared to a sham exposed group. However, SMF exposure failed to alter malondialdehyde (MDA) concentration (+6%, p > 0.05) and glutathione peroxidase (GPx) (-5%, p > 0.05), catalase (CAT) (-6%, p > 0.05) and superoxide dismutase (SOD) activities (+38%, p > 0.05) in group 3 compared to the sham exposed group. DNA analysis by single cell gel electrophoresis (comet assay) revealed that SMF exposure did not exert any DNA damage in groups 1 and 2. However, it induced a low level of DNA single strand breaks in cells of group 3. To further explore the oxidative DNA damage, cellular DNA for group 3 was isolated, hydrolyzed and analysed by HPLC-EC. The level of 8-oxodGuo in this group remained unchanged compared to the sham exposed group (+6.5%, p > 0.05). Cells stained with zinc-specific fluorescent probes zinpyr-1 showed a decrease of labile zinc fraction in all groups exposed to SMF. Our data showed that SMF exposure (250 mT, during 3 h) did not cause oxidative stress and DNA damage in THP1 cells. However, SMF could alter the intracellular labile zinc fraction.

  18. Desarrollo tecnológico de la formulación de cápsulas de ampicilina 250 y 500 mg

    Directory of Open Access Journals (Sweden)

    María Antonia Serrate

    1997-08-01

    Full Text Available Se describió el desarrollo tecnológico para la formulación de cápsulas de ampicilina trihidratada, reutilizando los finos que se obtienen de la tecnología por vía seca y que representan el 30 % de ésta. Se utilizó la vía húmeda por las características del fino obtenido y se logró un producto actualizado y con las características adecuadas para su uso. Las cápsulas de 250 y 500 mg fueron sometidas a estudio de estabilidad a temperaturas controladas y se determinaron las características físicoquímicas que debe cumplir el granulado. Esta reutilización de los finos, producto de la vía seca, logra un aprovechamiento óptimo de la materia prima que se dedica a esta producción.The technological development to produce the formulation of capsules of ampicillin trihydrate using again the products obtained through the dry procedure representing the 30 % of it, is described. A wet procedure was used because of the characteristics of the powder obtained and a current product was obtained having the proper characteristics for its use. Capsules of 250 and 500 mg were subjected to stability studies at controlled temperature and the physical and chemical characteristics that may comply with the granulate were also determined. This reutilization of fine products through the dry procedure makes it possible to attain an optimun use of the raw material employed for this production.

  19. [250 years of English psychiatry].

    Science.gov (United States)

    Freeman, H

    1996-08-01

    The history of British psychiatry is considered from five main viewpoints: clinical practice, the institutional basis, the legislative basis, lay perspectives of-mental disorder, and European influences. Its philosophical basis can be traced back to the work of the seventeenth-century philosophers. Thomas Hobbes and John Locke. In Scotland, both 'philosophy of mind' and new clinical methods flourished during its Enlightenment; the concept of 'neurosis' was developed by William Cullen. Around 1800, James Prichard's concept of 'moral insanity' became the foundation of modern work on personality disorder and psychopathy. The psychotic illness of King George III, beginning in 1788, led to greater public sympathy for the mentally ill. Attitudes since then have varied, with 'antipsychiatry' becoming very influential in the 1960s. By the mid-eighteenth century, specialised institutions for the mentally ill existed in a number of cities, there were also units attached to charitable general hospitals, but none of these continued after about 1830. The neglect of patients in private madhouses, prisons, and poorhouses led to increasing concern by Parliament, which resulted in the development of public asylums throughout the country. Severe legal restrictions on their activities were modified in 1930 and completely reformed in 1959. From the mid-nineteenth century, French and German influences became increasingly strong, but British universities played no active part in psychiatry until the 1950s. Psycho-analysis did not develop strongly in Britain, where the main contribution was through translation and biography, but some leading analysts came as refugees in the 1930s-as did other psychiatrists from central Europe. Another important influence was that of Adolf Meyer at the Institute of Psychiatry, London, particularly through Sir Aubrey Lewis; physical treatment methods also came to Britain from Europe. In the second half of this century, the most important British developments have been in social psychiatry therapeutic communities, day hospitals, comprehensive district services, psychogeriatrics, etc. Academic psychiatry has also become strong since the 1960s.

  20. 250,000 Families Campaign

    NARCIS (Netherlands)

    Sherwood, Stephen; Deaconu, Ana; Paredes, Myriam

    2017-01-01

    Innovation systems (IS) are taken to be coherent and consistent narratives or discourses. This chapter uses the Group/Grid or Cultural Theory (CT) to distinguish four competing IS narratives, each with their own theory of change, criterion variables, strategies, pathways of innovation and designs

  1. Spectral matching techniques (SMTs) and automated cropland classification algorithms (ACCAs) for mapping croplands of Australia using MODIS 250-m time-series (2000–2015) data

    Science.gov (United States)

    Teluguntla, Pardhasaradhi G.; Thenkabail, Prasad S.; Xiong, Jun N.; Gumma, Murali Krishna; Congalton, Russell G.; Oliphant, Adam; Poehnelt, Justin; Yadav, Kamini; Rao, Mahesh N.; Massey, Richard

    2017-01-01

    Mapping croplands, including fallow areas, are an important measure to determine the quantity of food that is produced, where they are produced, and when they are produced (e.g. seasonality). Furthermore, croplands are known as water guzzlers by consuming anywhere between 70% and 90% of all human water use globally. Given these facts and the increase in global population to nearly 10 billion by the year 2050, the need for routine, rapid, and automated cropland mapping year-after-year and/or season-after-season is of great importance. The overarching goal of this study was to generate standard and routine cropland products, year-after-year, over very large areas through the use of two novel methods: (a) quantitative spectral matching techniques (QSMTs) applied at continental level and (b) rule-based Automated Cropland Classification Algorithm (ACCA) with the ability to hind-cast, now-cast, and future-cast. Australia was chosen for the study given its extensive croplands, rich history of agriculture, and yet nonexistent routine yearly generated cropland products using multi-temporal remote sensing. This research produced three distinct cropland products using Moderate Resolution Imaging Spectroradiometer (MODIS) 250-m normalized difference vegetation index 16-day composite time-series data for 16 years: 2000 through 2015. The products consisted of: (1) cropland extent/areas versus cropland fallow areas, (2) irrigated versus rainfed croplands, and (3) cropping intensities: single, double, and continuous cropping. An accurate reference cropland product (RCP) for the year 2014 (RCP2014) produced using QSMT was used as a knowledge base to train and develop the ACCA algorithm that was then applied to the MODIS time-series data for the years 2000–2015. A comparison between the ACCA-derived cropland products (ACPs) for the year 2014 (ACP2014) versus RCP2014 provided an overall agreement of 89.4% (kappa = 0.814) with six classes: (a) producer’s accuracies varying

  2. Application of the Cavity theory in the calibration of the powder TLD-100 for energies of 60 Co, 137 Cs, 192 Ir and RX 50, 250 k Vp

    International Nuclear Information System (INIS)

    Loaiza C, S.P.; Alvarez R, J.T.

    2006-01-01

    A powder lot TLD-100 (LiF:Mg,Ti) in absorbed dose terms in water D w for the following radiation sources: 60 Co, 137 Cs and RX 50 and 250 k Vp is calibrated; to continuation is made a lineal interpolation of the TLD response in function of the effective energy of the sources to calibrate a source of 192 Ir. The calibration of those fields in D w are carried out with aid of the Bragg-Gray cavity theory, the one which finds implicit in the following protocols: IAEA-TRS 398 for the 60 Co and the AAPM TG61 for X Rays of 50 and 250 k Vp. Additionally the AAPM protocol TG43 to determine the D w in function of the kerma intensity S k in the case of the 137 Cs is used. The calibration curves for the response of the TLD-100 R TLD vs D w , corresponding to each one of the sources already mentioned are constructed. The R TLD vs D w by least heavy square by means of a second order polynomial that corrects the supralineality of the response is adjusted. The curves are validated by lack of LOF adjustment and by the Anderson Darling normality test. Later the factors of sensitivity (F s ) for the sources of 192 Ir: Micro Selectron and Vari Source are interpolated, used respectively in the A and B hospitals for treatments of brachytherapy of high dose rate (HDR), the expanded uncertainties associated to the D w and F s are also determined. Finally, an acrylic phantom and a couple of capsules are already sent to the hospitals mentioned, to verify a nominal D w of 2 Gy, in a case an underestimate in 5.5% in the imparted D w and in other an overestimation in a range of -1.5 to -8.0% was obtained. The obtained results in this work establish the bases for the development of a national dosimetric quality control program for brachytherapy of HDR with sources of 192 Ir. (Author)

  3. A continuous 250,000 yr record of oxygen and carbon isotopes in ostracode and bulk-sediment carbonate from Bear Lake, Utah-Idaho

    Science.gov (United States)

    Bright, Jordon; Kaufman, D.S.; Forester, R.M.; Dean, W.E.

    2006-01-01

    Oxygen and carbon isotopes from a continuous, 120-m-long, carbonate-rich core from Bear Lake, Utah-Idaho, document dramatic fluctuations in the hydrologic budget of the lake over the last 250,000 yr. Isotopic analyses of bulk sediment samples capture millennial-scale variability. Ostracode calcite was analyzed from 78 levels, mainly from the upper half of the core where valves are better preserved, to compare the isotopic value of purely endogenic carbonate with the bulk sediment, which comprises both endogenic and detrital components. The long core exhibits three relatively brief intervals with abundant endogenic aragonite (50??10%) and enriched ??18O and ??13C. These intervals are interpreted as warm/dry periods when the lake retracted into a topographically closed basin. We correlate these intervals with the interglacial periods of marine oxygen-isotope stages 1, 5e, and 7a, consistent with the presently available geochronological control. During most of the time represented by the core, the lake was fresher than the modern lake, as evidenced by depleted ??18O and ??13C in bulk-sediment carbonate. ?? 2006 Elsevier Ltd. All rights reserved.

  4. Heavy-Atom Tunneling Calculations in Thirteen Organic Reactions: Tunneling Contributions are Substantial, and Bell's Formula Closely Approximates Multidimensional Tunneling at ≥250 K.

    Science.gov (United States)

    Doubleday, Charles; Armas, Randy; Walker, Dana; Cosgriff, Christopher V; Greer, Edyta M

    2017-10-09

    Multidimensional tunneling calculations are carried out for 13 reactions, to test the scope of heavy-atom tunneling in organic chemistry, and to check the accuracy of one-dimensional tunneling models. The reactions include pericyclic, cycloaromatization, radical cyclization and ring opening, and S N 2. When compared at the temperatures that give the same effective rate constant of 3×10 -5  s -1 , tunneling accounts for 25-95 % of the rate in 8 of the 13 reactions. Values of transmission coefficients predicted by Bell's formula, κ Bell  , agree well with multidimensional tunneling (canonical variational transition state theory with small curvature tunneling), κ SCT . Mean unsigned deviations of κ Bell vs. κ SCT are 0.08, 0.04, 0.02 at 250, 300 and 400 K. This suggests that κ Bell is a useful first choice for predicting transmission coefficients in heavy-atom tunnelling. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. The scientific measurement and evaluation programme (WMEP). Annual evaluation 1996; Wissenschaftliches Mess- und Evaluierungsprogramm (WMEP) zum Breitentest '250 MW Wind'. Jahresauswertung 1996

    Energy Technology Data Exchange (ETDEWEB)

    Durstewitz, M.; Ensslin, C.; Hahn, B.; Hoppe-Klipper, M. (comps.)

    1997-07-01

    The Bundesministerium fuer Bildung, Wissenschaft, Forschung und Technik (B.M.B.F.-Federal Ministry for Education, Science, Research and Technology) funds the '250 MW Wind' test programme. This programme is designed to acquire statistically relevant data concerning the practical use of wind energy converters (WECs) in the Federal Republic of Germany. The technological and scientific areas of this supportive measure, the 'Wissenschaftliche Mess- und Evaluierungsprogramm' (WMEP - Scientific Measurement and Evaluation Programme), are implemented by the Institut fuer Solare Energieversorgungstechnik (ISET - Institute for Solar Energy Supply Technology) in Kassel. The WMEP acquires and evaluates performance data concerning all funded WECs for a 10 year period. The following areas are the main focal points of the programme: Wind Resources: Local and regional distribution of wind resources in Germany, wind conditions at specific sites. WEC Performance: Energy production and consumption of WECs, periods of grid interconnection, periods of full and partial load, performance characteristics. Reliability: Technical availability, causes of faults, malperformance, component failure. Economics: Income through the operation of the WEC, costs related to maintenance, repair and insurance. Intensive statistical evaluations concerning these focal points are implemented, based on the continuously acquired operational data of each WEC. The results are presented in this report, in a form compatible to the evaluations of recent years. (orig.)

  6. Vapour liquid equilibria of monocaprylin plus palmitic acid or methyl stearate at P = (1.20 and 2.50) kPa by using DSC technique

    International Nuclear Information System (INIS)

    Cunico, Larissa P.; Damaceno, Daniela S.; Matricarde Falleiro, Rafael M.; Sarup, Bent; Abildskov, Jens; Ceriani, Roberta; Gani, Rafiqul

    2015-01-01

    Highlights: • Novel VLE data for binary mixtures involving a partial acylglycerol (monocaprylin). • Use of a promising technique for measuring VLE/vapour pressure data (DSC technique). • The consistency of experimental data is analysed by a proposed methodology. • Regressed parameters are given for excess Gibbs thermodynamic models. • New regressed parameters are presented for UNIFAC to account for nonidealities. - Abstract: The Differential Scanning Calorimetry (DSC) technique is used for measuring isobaric (vapour + liquid) equilibria for two binary mixtures: {monocaprylin + palmitic acid (system 1) or methyl stearate (system 2)} at two different pressures P = (1.20 and 2.50) kPa. The obtained PTx data are correlated by Wilson, NRTL and UNIQUAC models. The original UNIFAC group contribution method is also considered and new binary interaction parameters for the main groups CH 2 , CCOO, OH and COOH are regressed, to account for the non-idealities found in these lipid systems. Established thermodynamic consistency tests are applied and attest the quality of the measured data. In terms of relevance of the selected components, system 1 can be found in the purification and deodorization steps during the production of edible oils, while, system 2 can be found in the purification steps of biodiesel. It should be noted that no such data could be found in the open literature, not only for the specific components selected but also for the combination of the classes of components considered; that is, acylglycerol plus fatty acid or fatty ester.

  7. Stream-sediment samples reanalyzed for major, rare earth, and trace elements from ten 1:250,000-scale quadrangles, south-central Alaska, 2007-08

    Science.gov (United States)

    Bailey, Elizabeth A.; Shew, Nora B.; Labay, Keith A.; Schmidt, Jeanine M.; O'Leary, Richard M.; Detra, David E.

    2010-01-01

    During the 1960s through the 1980s, the U.S. Geological Survey (USGS) conducted reconnaissance geochemical surveys of the drainage basins throughout most of the Anchorage, Bering Glacier, Big Delta, Gulkana, Healy, McCarthy, Mount Hayes, Nabesna, Talkeetna Mountains, and Valdez 1:250,000-scale quadrangles in Alaska as part of the Alaska Mineral Resource Assessment Program (AMRAP). These geochemical surveys provide data necessary to assess the potential for undiscovered mineral resources on public and other lands, and provide data that may be used to determine regional-scale element baselines. This report provides new data for 366 of the previously collected stream-sediment samples. These samples were selected for reanalysis because recently developed analytical methods can detect additional elements of interest and have lower detection limits than the methods used when these samples were originally analyzed. These samples were all analyzed for arsenic by hydride generation atomic absorption spectrometry (HGAAS), for gold, palladium, and platinum by inductively coupled plasma-mass spectrometry after lead button fire assay separation (FA/ICP-MS), and for a suite of 55 major, rare earth, and trace elements by inductively coupled plasma-atomic emission spectrometry and inductively coupled plasma-mass spectrometry (ICP-AES-MS) after sodium peroxide sinter at 450 degrees Celsius.

  8. Calendar aging of a 250 kW/500 kWh Li-ion battery deployed for the grid storage application

    Science.gov (United States)

    Kubiak, Pierre; Cen, Zhaohui; López, Carmen M.; Belharouak, Ilias

    2017-12-01

    The introduction of Li-ion batteries for grid applications has become evidence as the cost per kWh is continuously decreasing. Although the Li-ion battery is a mature technology for automotive applications and portable electronics, its use for stationary applications needs more validation. The Li-ion technology is considered safe enough for grid storage application, but its lifetime is generally evaluated to be around 10 years. Higher market penetration will be achieved if a longer lifespan could be demonstrated. Therefore, aging evaluation of the batteries becomes crucial. In this paper we investigated the effects of aging after a three years' standby field deployment of a 250 kW/500 kWh Li-ion battery integrated with the grid and solar farm under the harsh climate conditions of Qatar. The development of tools for acquisition and analysis of data from the battery management system (BMS) allows the assessment of the battery performance at the battery stack, string and cell levels. The analysis of the residual capacity after aging showed that the stack suffered from a low decrease of capacity, whereas some inconsistencies have been found between the strings. These inconsistencies are caused by misalignment of a small number of cells that underwent self-discharge during standby at high state of charge.

  9. Effect of post-weld heat treatments on strength and toughness behavior of T-250 maraging steel welded by laser beam

    International Nuclear Information System (INIS)

    Li, Kun; Shan, Jiguo; Wang, Chunxu; Tian, Zhiling

    2016-01-01

    This paper elucidates here the strength and toughness behavior of T-250 maraging steel welded by laser beam under different approaches of three post-weld heat treatments, i.e. aging (A), solutionizing+aging (SA) and homogenizing+solutionizing+aging (HSA). The microstructures of the weld metals with A and SA processes both comprised of finely dispersive Ni 3 (Ti, Mo) precipitates, small martensite lath and reverted austenite along the grain boundary. However, in the weld metal with HSA process, it exhibited the same Ni 3 (Ti, Mo) precipitate with the large martensite lath and the absence of reverted austenite. The ultimate tensile strength and static toughness of the welded joint with HSA process were 1350.6 MPa and 63.8 MJ m −3 , respectively. The static toughness has been remarkably improved from 71% to 91% of the applied parent metal compared with that of the welded joint with A process. The present study underscores that the Ni 3 (Ti, Mo) precipitate and martensite are significant to ensure the high strength of welded joints. Due to its inconsistent deformation with the matrix of martensite, the reverted austenite has a notable influence on the toughness of welded joints. It shows that the post-weld heat treatments of HSA process can influence the mechanical behavior of welded joints by eliminating the reverted austenite.

  10. Geochemical provenance of anomalous metal concentrations in stream sediments in the Ashton 1:250,000 quadrangle, Idaho/Montana/Wyoming

    International Nuclear Information System (INIS)

    Shannon, S.S. Jr.

    1982-01-01

    Stream-sediment samples from 1500 sites in the Ashton, Idaho/Montana/Wyoming 1:250,000 quadrangle were analyzed for 45 elements. Almost all samples containing anomalous concentrations (exceeding one standard deviation above the mean value of any element) were derived from drainage basins underlain by Quaternary rhyolite, Tertiary andesite or Precambrian gneiss and schist. Aluminum, barium, calcium, cobalt, iron, nickel, magnesium, scandium, sodium, strontium, and vanadium have no andesite provenance. Most anomalous manganese, europium, hafnium, and zirconium values were derived from Precambrian rocks. All other anomalous elemental concentrations are related to Quaternary rhyolite. This study demonstrates that multielemental stream-sediment analyses can be used to infer the provenance of stream sediments. Such data are available for many parts of the country as a result of the National Uranium Resource Evaluation. This study suggests that stream-sediment samples collected in the Rocky Mountains can be used either as pathfinders or as direct indicators to select targets for mineral exploration for a host of metals

  11. Production asymmetry of $\\Lambda^0$ and ${\\overline{\\Lambda}}^0$ in $\\pi^{\\pm}$, $K^{\\pm}$, p - nucleon collisions at 250 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Nicola, Marcello Santo [Brazilian Center for Physics Research, Rio de Janeiro (Brazil)

    2001-02-01

    Using data from Fermilab xed-target experiment E769, we have measured particleantiparticle production asymmetries for Λ0 hyperons in π± - nucleon interactions, K ± - nucleon interactions and p - nucleon interactions at 250 GeV/c. The asymmetries are measured as functions of Feynman-x (xf ) and pT2 over the ranges 0 ≤ pT2 ≤ 4(GeV/c)2 and -0.12 ≤ xF ≤ 0.12 (for positive beam) and 0 ≤ pT2 ≤ 10(GeV/c)2 and -0.16 ≤ xF ≤ 0:.0 for the negative beam. We find substantial asymmetries, even at xF = 0. We also observe leading-particle-type asymmetries which qualitatively agree with theoretical predictions.

  12. Systemic Therapy after Radiotherapy Significantly Reduces the Risk of Mortality of Patients with 1-3 Brain Metastases: A Retrospective Study of 250 Patients.

    Science.gov (United States)

    Li, Bo; Dai, Zhao-Xia; Chen, Yi-Dong; Liu, Yan-Wei; Liu, Shuai; Gu, Xue-Nan; Qiu, Xiao-Guang

    2017-12-20

    For patients with a brain metastasis (BM), systemic therapy is usually administered after the completion of radiotherapy, especially in cases of multiple BMs. However, the role of systemic therapy in patients with a limited number of BMs is not clear. Therefore, we conducted a retrospective study to explore this question. Consecutive patients with a pathologically confirmed malignancy and 1-3 intracranial lesions that had been documented within the last decade were selected from the databases of three hospitals in China. A total of 250 patients were enrolled; of them, 135 received radiotherapy alone and 115 received radiotherapy plus systemic therapy. In patients receiving whole-brain radiation therapy (WBRT) as radiotherapy, 28 received WBRT alone and 35 patients received WBRT plus systemic therapy. Of the patients treated with stereotactic radiosurgery (SRS), 107 received SRS alone and 80 received SRS plus systemic therapy. Multivariate analysis revealed that systemic therapy significantly reduced the risk of mortality compared with radiotherapy alone (hazard ratio [HR] = 0.294, 95% confidence interval [CI] = 0.158-0.548). Further, when the analysis was conducted in subgroups of WBRT (HR = 0.230, 95% CI = 0.081-0.653) or SRS (HR = 0.305, 95% CI = 0.127-0.731), systemic therapy still showed the ability to reduce the risk of mortality in patients with BMs. Systemic therapy after either SRS or WBRT radiotherapy may significantly reduce the risk of mortality of patients with 1-3 BMs.

  13. Experimental determination of the stabilities of Au 2S (cr) at 25 °C and Au(HS)2- at 25-250 °C

    Science.gov (United States)

    Tagirov, B. R.; Baranova, N. N.; Zotov, A. V.; Schott, J.; Bannykh, L. N.

    2006-07-01

    The solubility of (i) Au (cr), (ii) mixtures of crystalline Ag 2S-Ag 3AuS 2, and (iii) Ag 3AuS 2 (uytenbogaardtite)-AgAuS (petrovskaite) was measured at 25 °C, 1 bar, whereas the solubility of AgAuS (cr) was measured at 91-250 °C and P sat. These measurements were performed in aqueous sulphide solutions containing ˜0.012-0.12 m of total reduced sulfur. At 25 °C sealed glass ampoules were employed, and Ti autoclaves allowing sampling of experimental solutions were used at higher temperatures. It was found that under investigated experimental conditions AgAuS dissolves incongruently with the formation of Ag 3AuS 2. The values of the following equilibrium reaction constants were determined: Au+HS0(aq)+HS=Au(HS)2-+0.5H(i)K=K AgAuS+HS+0.5HS0(aq)=1.5AgS+Au(HS)2-(ii)K 1.5AgAuS+HS+0.5HS0(aq)=0.5AgAuS+Au(HS)2-(iii)K It was found that at 25 °C, 1 bar log K(i) = -5.62 ± 0.14, log K(ii) = -4.49 ± 0.26 and log K(iii) = -4.03 ± 0.15. Solubility data collected at higher temperatures resulted in the following values for log K(iii): -2.12 ± 0.25, -1.32 ± 0.12, and -1.04 ± 0.08 at 91, 150, and 250 °C, respectively (the latter value corresponds to the reaction 1.97 AgAuS+HS+0.5HS0(aq)=0.735AgAuS+Au(HS)2- because Ag 3AuS 2(cr) undergoes a phase transition at 183 °C). These values are in good agreement with log K(iii) = -2.81 ± 0.10 obtained at 80 °C by Zotov et al. (Zotov, A.V., Baranova, N.N., Bannykh, L.N., 1996. Solubility of the gold sulfides Au 2S and AgAuS in solutions containing hydrogen sulfide at 25-80 °C and pressures of 1 and 500 bar. Geochem. Int.34, 216-221). The values of K(ii) and K(iii) determined in the present study were combined with the thermodynamic properties of Ag-Au sulphides reported by Osadchii and Rappo (Osadchii, E.G., Rappo, O.A., 2004. Determination of standard thermodynamic properties of sulfides in the Ag-Au-S system by means of a solid-state galvanic cell. Am. Miner.89, 1405-1410), and thermodynamic properties for aqueous species and

  14. Voltage balancing: Long-term experience with the 250 V supercapacitor module of the hybrid fuel cell vehicle HY-LIGHT

    Science.gov (United States)

    Kötz, R.; Sauter, J.-C.; Ruch, P.; Dietrich, P.; Büchi, F. N.; Magne, P. A.; Varenne, P.

    On the occasion of the "Challenge Bibendum" 2004 in Shanghai, the hybrid fuel cell-supercapacitor vehicle HY-LIGHT, a joint project of Conception et Développement Michelin and the Paul Scherrer Institut, was presented to the public. The drive train of this vehicle comprises a 30 kW polymer electrolyte fuel cell (PEFC) and a 250 V supercapacitor (SC) module for energy recuperation and boost power during short acceleration and start-up processes. The supercapacitor module was deliberately constructed without continuous voltage balancing units. The performance of the supercapacitor module was monitored over the 2 years of operation particularly with respect to voltage balancing of the large number of SC cells connected in series. During the investigated period of 19 months and about 7000 km driving, the voltage imbalance within the supercapacitor module proved negligible. The maximum deviation between best and worst SC was always below 120 mV and the capacitor with the highest voltage never exceeded the nominal voltage by more than 40 mV.

  15. Mapping rice-fallow cropland areas for short-season grain legumes intensification in South Asia using MODIS 250 m time-series data

    Science.gov (United States)

    Gumma, Murali Krishna; Thenkabail, Prasad S.; Teluguntla, Pardhasaradhi G.; Rao, Mahesh N.; Mohammed, Irshad A.; Whitbread, Anthony M.

    2016-01-01

    The goal of this study was to map rainfed and irrigated rice-fallow cropland areas across South Asia, using MODIS 250 m time-series data and identify where the farming system may be intensified by the inclusion of a short-season crop during the fallow period. Rice-fallow cropland areas are those areas where rice is grown during the kharif growing season (June–October), followed by a fallow during the rabi season (November–February). These cropland areas are not suitable for growing rabi-season rice due to their high water needs, but are suitable for a short -season (≤3 months), low water-consuming grain legumes such as chickpea (Cicer arietinum L.), black gram, green gram, and lentils. Intensification (double-cropping) in this manner can improve smallholder farmer’s incomes and soil health via rich nitrogen-fixation legume crops as well as address food security challenges of ballooning populations without having to expand croplands. Several grain legumes, primarily chickpea, are increasingly grown across Asia as a source of income for smallholder farmers and at the same time providing rich and cheap source of protein that can improve the nutritional quality of diets in the region. The suitability of rainfed and irrigated rice-fallow croplands for grain legume cultivation across South Asia were defined by these identifiers: (a) rice crop is grown during the primary (kharif) crop growing season or during the north-west monsoon season (June–October); (b) same croplands are left fallow during the second (rabi) season or during the south-east monsoon season (November–February); and (c) ability to support low water-consuming, short-growing season (≤3 months) grain legumes (chickpea, black gram, green gram, and lentils) during rabi season. Existing irrigated or rainfed crops such as rice or wheat that were grown during kharif were not considered suitable for growing during the rabi season, because the moisture/water demand of these crops is too high. The

  16. High time resolution observations of the polar stratosphere and mesosphere using a ground-based 230-250 GHz microwave radiometer

    Science.gov (United States)

    Newnham, D. A.; Espy, P. J.; Clilverd, M. A.; Maxfield, D. J.; Hartogh, P.; Holmén, K.; Blindheim, S.; Horne, R. B.

    2012-04-01

    Microwave radiometry is used to measure thermal emission by the Doppler- and pressure-broadened molecular rotational lines of atmospheric gases, from which vertical abundance profiles can be determined. Since solar radiation is not required for the measurement, the technique has the advantage that continuous observations are possible including throughout the polar winter. We describe the development of a passive microwave radiometer [Espy, P. J., P. Hartogh, and K. Holmen (2006), Proc. SPIE, 6362, 63620P, doi:10.1117/12.688953] for ground-based remote sensing of the polar middle atmosphere. The instrument measures nitric oxide (NO), ozone (O3), and carbon monoxide (CO) vertical profiles over the altitude range 35-90 km with time resolution as high as 15 minutes, allowing the diurnal variability of trace chemical species to be investigated. Heterodyne detection of atmospheric emission at 230 GHz and 250 GHz (wavelength ~1.25 mm) with a receiver noise temperature of 300 K is achieved using a superconductor-insulator-superconductor (SIS) mixer cooled to 4 K. The down-converted signals at 1.35 GHz and 2.10 GHz are analysed using both a moderate-resolution (28 kHz, 220 MHz bandwidth) and a high-resolution (14 kHz, 40 MHz bandwidth) chirp-transform spectrometer (CTS). The instrument was operated semi-autonomously at Troll station (72° 01'S 02° 32'E, 1270 m above sea level), Antarctica during 2008-10 and at the Arctic LIDAR Observatory for Middle Atmosphere Research (ALOMAR, 69° 16'N, 16° 00'E, 380 m above sea level), northern Norway during 2011-12. NO volume mixing ratio (VMR) profiles have been inverted from calibrated brightness temperature spectra of the NO line centred at 250.796 GHz, observed above Troll station, using the Microwave Observation Line Estimation and Retrieval (MOLIERE) version 5 code. A priori pressure, temperature, ozone, water vapour, and NO profiles above 30 km were calculated using the Sodankylä Ion and Neutral Chemistry (SIC, version 6

  17. Saving Salmon Through Advances in Fluvial Remote Sensing: Applying the Optimal Band Ratio Analysis (OBRA) for Bathymetric Mapping of Over 250 km of River Channel and Habitat Classification

    Science.gov (United States)

    Richardson, R.; Legleiter, C. J.; Harrison, L.

    2015-12-01

    Salmonids are threatened with extinction across the world from the fragmentation of riverine ecosystems from dams and diversions. In California, efforts to expand the range of spawnable habitat for native salmon by transporting fish around reservoirs is a potentially species saving idea. But, strong scientific evidence of the amount of high quality habitat is required to make these difficult management decisions. Remote sensing has long been used in fluvial settings to identify physical parameters that drive the quality of aquatic habitat; however, the true strength of remote sensing to cover large spatial extents has not been applied with the resolution that is relevant to salmonids. This project utilizes hyperspectral data of over 250 km of the Tuolumne and Merced Rivers to extract depth and bed slope from the wetted channel and NIR LiDAR for the surrounding topography. The Optimal Band Ratio Analysis (OBRA) has proven as an effective tool to create bathymetric maps of river channels in ideal settings with clear water, high amounts of bottom reflectance, and less than 3 meters deep over short distances. Results from this study show that OBRA can be applied over larger riverscapes at high resolutions (0.5 m). The depth and bed slope estimations are used to classify habitat units that are crucial to quantifying the quality and amount of habitat in these river that once produced large populations of native salmonids. As more managers look to expand habitat for these threatened species the tools developed here will be cost effective over the large extents that salmon migrate to spawn.

  18. Soil contaminated phyto remediation of Pb and cd metal by using rice straw fermented by trichoderma viride that given exposure 250 gray doses of gamma radiation

    International Nuclear Information System (INIS)

    Yullita SL Andini; Hendrawati; Tri Retno Diah Larasati; Nana Mulyana

    2015-01-01

    Soil contamination by lead (Pb) and cadmium (Cd) is one form of environmental pollution that is harmful to living organisms. One way to resolve this problem by using phyto remediation with rice straw fermented by Trichoderma viride that given exposure 250 gray doses of gamma radiation. The purpose of this study was to look at the effect of Trichoderma viride fermented hay to improve the ability of Pb and Cd accumulation in the root zone of plants sweet corn (Zea Mays). There are three stages in the research process, namely the stages of SSF (Solid State Fermentation), incorporation, and Land farming. The fermentation process is done during the 16-day trial. Furthermore, the results of the SSF (Solid State Fermentation) mixed in soil that has been contaminated with heavy metals showed that administration of straw result SSF real impact on the value of pH, water content of the four treated samples. Results incorporation process and then applied with a crop of sweet corn (Zea Mays). Accumulation of heavy metals in sweet corn plant, analyzed by AAS analysis instrumentation. The measurement results show that the accumulation of Pb in the roots of plants in the sample K amounted to 33.66 mg/Kg, A sample of 26.80 mg/Kg, the sample B of 51.47 mg/kg, and sample C of 55.70 mg/Kg. While the metals Cd uptake in the roots of corn plants in the sample K showed Cd uptake of 269.65 mg/Kg, the sample A of 445.70 mg/Kg, the sample B of 337.17 mg/Kg and sample C of 336.72 mg/Kg. The phyto remediation process takes place based on the fito-stabilization principle. (author)

  19. Evaluation of the menisci of the knee joint using three-dimensional isotropic resolution fast spin-echo imaging: diagnostic performance in 250 patients with surgical correlation

    Energy Technology Data Exchange (ETDEWEB)

    Kijowski, Richard; Davis, Kirkland W.; Blankenbaker, Donna G.; Woods, Michael A.; De Smet, Arthur A. [University of Wisconsin School of Medicine and Public Health, Department of Radiology, Madison, WI (United States); Munoz del Rio, Alejandro [University of Wisconsin School of Medicine and Public Health, Department of Radiology, Madison, WI (United States); University of Wisconsin School of Medicine and Public Health, Department of Statistics, Madison, WI (United States)

    2012-02-15

    To compare the diagnostic performance of FSE-Cube, a three-dimensional isotropic resolution intermediate-weighted fast spin-echo sequence, with a routine magnetic resonance (MR) protocol at 3.0 T for detecting surgically confirmed meniscal tears of the knee joint in a large patient population. FSE-Cube was added to a routine MR protocol performed at 3.0 T on 250 patients who underwent subsequent knee arthroscopy. Three radiologists independently used FSE-Cube during one review and the routine MR protocol during a second review to detect medial and lateral meniscal tears. Using arthroscopy as the reference standard, the sensitivity and specificity of FSE-Cube and the routine MR protocol for detecting meniscal tears were determined for all readers combined. McNemar's tests were used to compare diagnostic performance between FSE-Cube and the routine MR protocol. FSE-cube and the routine MR protocol had similar sensitivity (95.5%/95.3% respectively, P=0.94) and similar specificity (69.8%/74.0% respectively, P=0.10) for detecting 156 medial meniscal tears. FSE-Cube had significantly lower sensitivity than the routine MR protocol (79.4%/85.0% respectively, P < 0.05) but similar specificity (83.9%/82.2% respectively, P=0.37) for detecting 89 lateral mensical tears. For lateral meniscal tears, FSE-Cube had significantly lower sensitivity (P < 0.05) than the routine MR protocol for detecting 19 root tears but similar sensitivity (P=0.17-1.00) for detecting all other tear locations and types. FSE-Cube had diagnostic performance similar to a routine MR protocol for detecting meniscal tears except for a significantly lower sensitivity for detecting lateral meniscal tears, which was mainly attributed to decreased ability to identify lateral meniscus root tears. (orig.)

  20. Evaluation of the menisci of the knee joint using three-dimensional isotropic resolution fast spin-echo imaging: diagnostic performance in 250 patients with surgical correlation

    International Nuclear Information System (INIS)

    Kijowski, Richard; Davis, Kirkland W.; Blankenbaker, Donna G.; Woods, Michael A.; De Smet, Arthur A.; Munoz del Rio, Alejandro

    2012-01-01

    To compare the diagnostic performance of FSE-Cube, a three-dimensional isotropic resolution intermediate-weighted fast spin-echo sequence, with a routine magnetic resonance (MR) protocol at 3.0 T for detecting surgically confirmed meniscal tears of the knee joint in a large patient population. FSE-Cube was added to a routine MR protocol performed at 3.0 T on 250 patients who underwent subsequent knee arthroscopy. Three radiologists independently used FSE-Cube during one review and the routine MR protocol during a second review to detect medial and lateral meniscal tears. Using arthroscopy as the reference standard, the sensitivity and specificity of FSE-Cube and the routine MR protocol for detecting meniscal tears were determined for all readers combined. McNemar's tests were used to compare diagnostic performance between FSE-Cube and the routine MR protocol. FSE-cube and the routine MR protocol had similar sensitivity (95.5%/95.3% respectively, P=0.94) and similar specificity (69.8%/74.0% respectively, P=0.10) for detecting 156 medial meniscal tears. FSE-Cube had significantly lower sensitivity than the routine MR protocol (79.4%/85.0% respectively, P < 0.05) but similar specificity (83.9%/82.2% respectively, P=0.37) for detecting 89 lateral mensical tears. For lateral meniscal tears, FSE-Cube had significantly lower sensitivity (P < 0.05) than the routine MR protocol for detecting 19 root tears but similar sensitivity (P=0.17-1.00) for detecting all other tear locations and types. FSE-Cube had diagnostic performance similar to a routine MR protocol for detecting meniscal tears except for a significantly lower sensitivity for detecting lateral meniscal tears, which was mainly attributed to decreased ability to identify lateral meniscus root tears. (orig.)

  1. Change of Cr atoms distribution in Fe85Cr15 alloy caused by 250 keV He+ ion irradiation to different doses

    International Nuclear Information System (INIS)

    Dubiel, S.M.; Żukrowski, J.

    2015-01-01

    Highlights: • Effect of He-ion irradiation dose on Fe 85 Cr 15 alloy. • Irradiation-induced clustering of Cr atoms. • Irradiation-caused reorientation of the surface magnetization vector. • Irradiation-caused increase of Fe-site spin-density. - Abstract: Redistribution of Cr atoms in a Fe 85 Cr 15 alloy caused by its irradiation with 250 keV He + ions to different doses, D = 8 ⋅ 10 16 , 16 ⋅ 10 16 and 48 ⋅ 10 16 ions/cm 2 was investigated by means of conversion electrons Mössbauer spectroscopy. The redistribution was expressed in terms of the Warren–Cowley short-range order parameters α 1 , α 2 and α 12 pertaining to the first (1NN), second (2NN) and both i.e. 1NN + 2NN shells, respectively. Clear evidence was found, both for non-irradiated and irradiated samples that the actual distribution of Cr atoms is characteristic of the shell, and for a given shell it depends on the irradiation dose. In particular, α 1 is positive, hence indicates an under population of Cr atoms in 1NN with respect to the random case, α 2 is negative, giving evidence thereby that 2NN is overpopulated by Cr atoms, and α 12 is weakly positive. Under the applied irradiation the number of Cr atoms in both neighbor shells decreased signifying thereby a clustering of Cr atoms. The underlying decrease of Cr concentration within the 1NN–2NN volume around the probe Fe atoms was estimated at 1.5 at.% ranging between 2.1 for the lowest and 0.8 at.% for the highest dose

  2. Major- and trace-element concentrations in rock samples collected in 2004 from the Taylor Mountains 1:250,000-scale quadrangle, Alaska

    Science.gov (United States)

    Klimasauskas, Edward P.; Miller, Marti L.; Bradley, Dwight C.; Karl, Sue M.; Baichtal, James F.; Blodgett, Robert B.

    2006-01-01

    The Kuskokwim mineral belt of Bundtzen and Miller (1997) forms an important metallogenic region in southwestern Alaska that has yielded more than 3.22 million ounces of gold and 400,000 ounces of silver. Precious-metal and related deposits in this region associated with Late Cretaceous to early Tertiary igneous complexes extend into the Taylor Mountains 1:250,000-scale quadrangle. The U.S. Geological Survey is conducting geologic mapping and a mineral resource assessment of this area that will provide a better understanding of the geologic framework, regional geochemistry, and may provide targets for mineral exploration and development. During the 2004 field season 137 rock samples were collected for a variety of purposes. The 4 digital files accompanying this report reflect the type of analysis performed and its intended purpose and are available for download as an Excel workbook, comma delimited format (*.csv), dBase 4 files (*.dbf) or as point coverages in ArcInfo interchange format (*.e00). Data values are provided in percent, pct (1gram per 100grams), or parts per million, ppm (1gram per 1,000,000grams) per the column heading in the table. All samples were analyzed for a suite of 42 trace-elements (icp42.*) to provide data for use in geochemical exploration as well as some baseline data. Selected samples were analyzed by additional methods; 104 targeted geochemical exploration samples were analyzed for gold, arsenic, and mercury (auashg.*); 21 of these samples were also analyzed to obtain concentrations of 10 loosely bound metals (icp10.*); 33 rock samples were analyzed for major element oxides to support the regional mapping program (reg.*), of which 28 sedimentary rock samples were also analyzed for total carbon, and carbonate carbon.

  3. New (p, ρ, T) data for carbon dioxide - Nitrogen mixtures from (250 to 400) K at pressures up to 20 MPa

    International Nuclear Information System (INIS)

    Mondejar, M.E.; Martin, M.C.; Span, R.; Chamorro, C.R.

    2011-01-01

    Highlights: → Densities of two mixtures of nitrogen and carbon dioxide are reported. → Experimental data are compared with calculated densities from the equation of state. → Experimental data agree with the equation of state for low pressures above 300 K. → The equation of state shows higher deviations than expected at high pressures. - Abstract: Comprehensive (p, ρ, T) measurements on two binary mixtures (0.10 CO 2 + 0.90 N 2 and 0.15 CO 2 + 0.85 N 2 ) were carried out in the gas phase at seven isotherms between (250 and 400) K and pressures up to 20 MPa using a single sinker densimeter with magnetic suspension coupling. A total of 69 (p, ρ, T) data for the first mixture and 69 (p, ρ, T) data for the second are presented in this article. The uncertainty in density was estimated to be (0.02 to 0.15)%, while the uncertainty in temperature was 3.9 mK and the uncertainty in pressure was less than 0.015% (coverage factor k = 2). Experimental results were compared with densities calculated from the GERG equation of state and with data reported by other authors for similar mixtures. Results yielded that, while deviations between experimental data and values calculated from the GERG equation were lower than 0.05% in density for low pressures, the relative error at high pressures and low temperatures increased to about (0.2 to 0.3)%. The main aim of this work was to contribute to an accurate density data base for CO 2 /N 2 mixtures and to check or improve equations of state existing for these binary mixtures.

  4. Opium addiction as an independent risk factor for coronary microvascular dysfunction: A case-control study of 250 consecutive patients with slow-flow angina.

    Science.gov (United States)

    Esmaeili Nadimi, Ali; Pour Amiri, Farah; Sheikh Fathollahi, Mahmood; Hassanshahi, Gholamhossien; Ahmadi, Zahra; Sayadi, Ahmad Reza

    2016-09-15

    Approximately 20% to 30% of patients who undergo coronary angiography for assessment of typical cardiac chest pain display microvascular coronary dysfunction (MCD). This study aimed to determine potential relationships between baseline clinical characteristics and likelihood of MCD diagnosis in a large group of patients with stable angina symptoms, positive exercise test and angiographic ally normal epicardial coronary arteries. This cross-sectional study included 250 Iranian with documented evidence of cardiac ischemia on exercise testing, class I or II indication for coronary angiography, and either: (1) angiographically normal coronary arteries and diagnosis of MCD with slow-flow phenomenon, or (2) normal angiogram and no evidence of MCD. All patients completed a questionnaire designed to capture key data including clinical demographics, past medical history, and social factors. Data was evaluated using single and multivariable logistic regression models to identify potential individual patient factors that might help to predict a diagnosis of MCD. 125 (11.2% of total) patients were subsequently diagnosed with MCD. 125 consecutive control subjects were selected for comparison. The mean age was similar among the two groups (52.38 vs. 53.26%, p=ns), but there was a higher proportion of men in the study group compared to control (42.4 vs. 27.2%, p=0.012). No significant relationships were observed between traditional cardiovascular risk factors (diabetes, hypertension, and dyslipidemia) or body mass index (BMI), and likelihood of MCD diagnosis. However, opium addiction was found to be an independent predictor of MCD on single and multivariable logistic regression model (OR=3.575, 95%CI: 1.418-9.016; p=0.0069). We observed a significant relationship between opium addiction and microvascular angina. This novel finding provides a potential mechanistic insight into the pathogenesis of MCD with slow-flow phenomenon. Copyright © 2016 Elsevier Ireland Ltd. All rights

  5. Reactions of CO2 with aqueous piperazine solutions: formation and decomposition of mono- and dicarbamic acids/carbamates of piperazine at 25.0 °C.

    Science.gov (United States)

    Conway, William; Fernandes, Debra; Beyad, Yaser; Burns, Robert; Lawrance, Geoffrey; Puxty, Graeme; Maeder, Marcel

    2013-02-07

    Piperazine (PZ) is widely recognized as a promising solvent for postcombustion capture (PCC) of carbon dioxide (CO(2)). In view of the highly conflicting data describing the kinetic reactions of CO(2)(aq) in piperazine solutions, the present study focuses on the identification of the chemical mechanism, specifically the kinetic pathways for CO(2)(aq) in piperazine solutions that form the mono- and dicarbamates, using the analysis of stopped-flow spectrophotometric kinetic measurements and (1)H NMR spectroscopic data at 25.0 °C. The complete set of rate and equilibrium constants for the kinetic pathways, including estimations for the protonation constants of the suite of piperazine carbamates/carbamic acids, is reported here using an extended kinetic model which incorporates all possible reactions for CO(2)(aq) in piperazine solutions. From the kinetic data determined in the present study, the reaction of CO(2)(aq) with free PZ was found to be the dominant reactive pathway. The superior reactivity of piperazine is confirmed in the kinetic rate constant determined for the formation of piperazine monocarbamic acid (k(7) = 2.43(3) × 10(4) M(-1) s(-1)), which is within the wide range of published values, making it one of the faster reacting amines. The corresponding equilibrium constant for the formation of the monocarbamic acid, K(7), markedly exceeds that of other monoamines. Kinetic and equilibrium constants for the remaining pathways indicate a minor contribution to the overall kinetics at high pH; however, these pathways may become more significant at higher CO(2) loadings and lower pH values where the concentrations of the reactive species are correspondingly higher.

  6. New (p, {rho}, T) data for carbon dioxide - Nitrogen mixtures from (250 to 400) K at pressures up to 20 MPa

    Energy Technology Data Exchange (ETDEWEB)

    Mondejar, M.E.; Martin, M.C. [Grupo de Termodinamica y Calibracion (TERMOCAL), Dpto. Ingenieria Energetica y Fluidomecanica, Escuela de Ingenierias Industriales, Universidad de Valladolid, Paseo del Cauce, 59, E-47011 Valladolid (Spain); Span, R. [Lehrstuhl fuer Thermodynamik, Fakultaet fuer Maschinenbau Gebaeude IB, Ebene 5, Ruhr-Universitaet Bochum, Universitaetsstr. 150, 44780 Bochum (Germany); Chamorro, C.R., E-mail: cescha@eis.uva.es [Grupo de Termodinamica y Calibracion (TERMOCAL), Dpto. Ingenieria Energetica y Fluidomecanica, Escuela de Ingenierias Industriales, Universidad de Valladolid, Paseo del Cauce, 59, E-47011 Valladolid (Spain)

    2011-12-15

    Highlights: > Densities of two mixtures of nitrogen and carbon dioxide are reported. > Experimental data are compared with calculated densities from the equation of state. > Experimental data agree with the equation of state for low pressures above 300 K. > The equation of state shows higher deviations than expected at high pressures. - Abstract: Comprehensive (p, {rho}, T) measurements on two binary mixtures (0.10 CO{sub 2} + 0.90 N{sub 2} and 0.15 CO{sub 2} + 0.85 N{sub 2}) were carried out in the gas phase at seven isotherms between (250 and 400) K and pressures up to 20 MPa using a single sinker densimeter with magnetic suspension coupling. A total of 69 (p, {rho}, T) data for the first mixture and 69 (p, {rho}, T) data for the second are presented in this article. The uncertainty in density was estimated to be (0.02 to 0.15)%, while the uncertainty in temperature was 3.9 mK and the uncertainty in pressure was less than 0.015% (coverage factor k = 2). Experimental results were compared with densities calculated from the GERG equation of state and with data reported by other authors for similar mixtures. Results yielded that, while deviations between experimental data and values calculated from the GERG equation were lower than 0.05% in density for low pressures, the relative error at high pressures and low temperatures increased to about (0.2 to 0.3)%. The main aim of this work was to contribute to an accurate density data base for CO{sub 2}/N{sub 2} mixtures and to check or improve equations of state existing for these binary mixtures.

  7. Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.

    Directory of Open Access Journals (Sweden)

    I-Ting Chow

    Full Text Available Susceptibility to type 1 diabetes (T1D is strongly associated with MHC class II molecules, particularly HLA-DQ8 (DQ8: DQA1*03:01/DQB1*03:02. Monitoring T1D-specific T cell responses to DQ8-restricted epitopes may be key to understanding the immunopathology of the disease. In this study, we examined DQ8-restricted T cell responses to glutamic acid decarboxylase 65 (GAD65 using DQ8 tetramers. We demonstrated that GAD65 121-140 and GAD65 250-266 elicited responses from DQ8+ subjects. Circulating CD4+ T cells specific for these epitopes were detected significantly more often in T1D patients than in healthy individuals after in vitro expansion. T cell clones specific for GAD65 121-140 and GAD65 250-266 carried a Th1-dominant phenotype, with some of the GAD65 121-140-specific T cell clones producing IL-17. GAD65 250-266-specific CD4+ T cells could also be detected by direct ex vivo staining. Analysis of unmanipulated peripheral blood mononuclear cells (PBMCs revealed that GAD65 250-266-specific T cells could be found in both healthy and diabetic individuals but the frequencies of specific T cells were higher in subjects with type 1 diabetes. Taken together, our results suggest a proinflammatory role for T cells specific for DQ8-restricted GAD65 121-140 and GAD65 250-266 epitopes and implicate their possible contribution to the progression of T1D.

  8. ICDP Project DeepCHALLA: Reconstructing 250,000 Years of Climate Change and Environmental History on the East African Equator

    Science.gov (United States)

    Wolff, C.; Verschuren, D.; Van Daele, M. E.; Waldmann, N.; Meyer, I.; Lane, C. S.; Van der Meeren, T.; Ombori, T.; Kasanzu, C.; Olago, D.

    2017-12-01

    Sediments on the bottom of Lake Challa, a 92-m deep crater lake on the border of Kenya and Tanzania near Mt. Kilimanjaro, contain a uniquely long and continuous record of past climate and environmental change in easternmost equatorial Africa. Supported in part by the International Continental Scientific Drilling Programme (ICDP), the DeepCHALLA project has now recovered this sediment record down to 214.8 m below the lake floor, with 100% recovery of the uppermost 121.3 m (the last 160 kyr BP) and ca.85% recovery of the older part of the sequence, down to the lowermost distinct reflector identified in seismic stratigraphy. This acoustic basement represents a ca.2-m thick layer of coarsely laminated, diatom-rich organic mud mixed with volcanic sand and silt deposited 250 kyr ago, overlying an estimated 20-30 m of unsampled lacustrine deposits representing the earliest phase of lake development. Down-hole logging produced profiles of in-situ sediment composition that confer an absolute depth- scale to both the recovered cores and the seismic stratigraphy. An estimated 74% of the recovered sequence is finely laminated (varved), and continuously so over the upper 72.3 m (the last 90 kyr). All other sections display at least cm-scale lamination, demonstrating persistence of a tranquil, profundal depositional environment throughout lake history. The sequence is interrupted only by 32 visible tephra layers 2 to 9 mm thick; and by several dozen fine-grained turbidites up to 108 cm thick, most of which are clearly bracketed between a non-erosive base and a diatom-laden cap. Tie points between sediment markers and the corresponding seismic reflectors support a preliminary age model inferring a near-constant rate of sediment accumulation over at least the last glacial cycle (140 kyr BP to present). This great time span combined with the exquisite temporal resolution of the Lake Challa sediments provides great opportunities to study past tropical climate dynamics at both short

  9. A Novel approach for monitoring cyanobacterial blooms using an ensemble based system from MODIS imagery downscaled to 250 metres spatial resolution

    Science.gov (United States)

    El Alem, A.; Chokmani, K.; Laurion, I.; El-Adlouni, S. E.

    2014-12-01

    In reason of inland freshwaters sensitivity to Harmful algae blooms (HAB) development and the limits coverage of standards monitoring programs, remote sensing data have become increasingly used for monitoring HAB extension. Usually, HAB monitoring using remote sensing data is based on empirical and semi-empirical models. Development of such models requires a great number of continuous in situ measurements to reach an acceptable accuracy. However, Ministries and water management organizations often use two thresholds, established by the World Health Organization, to determine water quality. Consequently, the available data are ordinal «semi-qualitative» and they are mostly unexploited. Use of such databases with remote sensing data and statistical classification algorithms can produce hazard management maps linked to the presence of cyanobacteria. Unlike standard classification algorithms, which are generally unstable, classifiers based on ensemble systems are more general and stable. In the present study, an ensemble based classifier was developed and compared to a standard classification method called CART (Classification and Regression Tree) in a context of HAB monitoring in freshwaters using MODIS images downscaled to 250 spatial resolution and ordinal in situ data. Calibration and validation data on cyanobacteria densities were collected by the Ministère du Développement durable, de l'Environnement et de la Lutte contre les changements climatiques on 22 waters bodies between 2000 and 2010. These data comprise three density classes: waters poorly ( 100,000 cells mL-1) loaded in cyanobacteria. Results were very interesting and highlighted that inland waters exhibit different spectral response allowing them to be classified into the three above classes for water quality monitoring. On the other, even if the accuracy (Kappa-index = 0.86) of the proposed approach is relatively lower than that of the CART algorithm (Kappa-index = 0.87), but its robustness is

  10. Current perceptions and practices surrounding the recognition and treatment of delirium in the intensive care unit: a survey of 250 critical care pharmacists from eight states.

    Science.gov (United States)

    Devlin, John W; Bhat, Shubha; Roberts, Russel J; Skrobik, Yoanna

    2011-10-01

    Pharmacists are key members of the intensive care unit (ICU) team; however, few data exist regarding their clinical role, perceptions, and current practices in recognizing and managing delirium. To describe current practices and perceptions of ICU pharmacists regarding delirium recognition and treatment relative to current recommendations. A self-administered survey was distributed to 457 pharmacists in 8 states who are members of the Society of Critical Care Medicine or the American College of Clinical Pharmacy and who spend 25% or more of their time providing clinical ICU pharmacy services. A total of 250 (55%) pharmacists responded. A delirium screening tool was routinely used by few (7%) pharmacists. Lack of time (34%) and the belief that screening is a nursing role (24%) were key barriers to pharmacist screenings. Most (85%) said that delirium should be pharmacologically managed; 68% responded that 2 or more medications should be used. The treatments of first choice included haloperidol (76%), an atypical antipsychotic (14%), or a benzodiazepine (10%). Frequently used treatments were haloperidol (87%), quetiapine (59%), and lorazepam (47%). Haloperidol was perceived by many (42%) to have 1 or more randomized trials supporting its use for delirium and Food and Drug Administration approval for this indication (34%). Haloperidol was most often administered on a scheduled basis (62%), intravenously (92%), and at a daily dose of 5-10 mg (58%). While the QTc interval was frequently measured at least once per shift using an electrocardiogram strip (64%), it was not routinely measured in 20% of ICUs, and 60% continued haloperidol when the QTc exceeded 500 msec. Current practices and perceptions surrounding recognition and treatment of delirium in patients in the ICU by the critical care pharmacists surveyed are heterogeneous. Antipsychotics are frequently recommended by pharmacists for delirium treatment, despite a lack of rigorous evidence to support their use. While

  11. Using MODIS True-Color 250 m Remote Sensing Data to Assess Interannual Variability of Suspended Matter over Southeastern Brazilian Continental Shelf

    Science.gov (United States)

    Belem, A. L.; Silva, T. M. L.; Albuquerque, A. L.

    2014-12-01

    Continental shelf is the final destination of terrigenous sediments drained by rivers and estuaries, forming a mass of water drifting over the shelf due to its differential density from underlaying salty oceanic waters, forming a coastal plume. On the Southeastern Brazilian Continental Shelf, Cabo Frio region represents the limit between Santos and Campos basin oil reserves. The continental drainage in this area is not expressive, nevertheless presents a complex interaction between the western boundary Brazil Current (BC) and shelf border mechanisms providing amid-shelf intrusion and a coastal upwelling of South Atlantic Central Water (SACW) over the shelf. Satellite images of the region shows expressive shelf plumes with sedimentary contributions from Paraiba do Sul river located approximately 180 km northward of Cabo Frio, as well as from Guanabara bay, located 150 km westward of Cabo Frio. In order to understand the role of plumes in sedimentary processes over the continental shelf, this study analyzed 10 years of MODIS true-color 250 m remote sensing data in order to understand the temporal variability of the shelf front and the area of plumes. The remote data were obtained from the Aerosol Robotic Network and USDA Foreign Agricultural Service subsets. Selected 17% of daily images were cloud-free to allow shelf plumes to be delimited and processed to enhancement of features as well as land masking, geo-referencing, and daily area calculation on pixel basis. During austral winter (dry season) the plumes get its maximum extension in area over the shelf, suggesting that the mechanism of sediment transport is connected with high energetic wave-wind interactions on the coast followed by wind-driven dispersion less than continental drainage. The interannual pattern shows a general decreasing trend, mainly in the last 4 years, associated with sediment availability on the inner shelf, which is driven by river discharge during the austral summer (rain season). We also

  12. Application of the Cavity theory in the calibration of the powder TLD-100 for energies of {sup 60} Co, {sup 137} Cs, {sup 192} Ir and RX 50, 250 k Vp; Aplicacion de la Teoria de la Cavidad en la calibracion de polvo TLD-100 para energias de {sup 60} Co, {sup 137} Cs, {sup 192} Ir y RX 50, 250 kVp

    Energy Technology Data Exchange (ETDEWEB)

    Loaiza C, S.P. [UAEM, Programa de Maestria en Fisica Medica, 50180, Toluca, Estado de Mexico (Mexico); Alvarez R, J.T. [ININ, 52750, Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: sandraplc_04@yahoo.com.mx

    2006-07-01

    A powder lot TLD-100 (LiF:Mg,Ti) in absorbed dose terms in water D{sub w} for the following radiation sources: {sup 60} Co, {sup 137} Cs and RX 50 and 250 k Vp is calibrated; to continuation is made a lineal interpolation of the TLD response in function of the effective energy of the sources to calibrate a source of {sup 192} Ir. The calibration of those fields in D{sub w} are carried out with aid of the Bragg-Gray cavity theory, the one which finds implicit in the following protocols: IAEA-TRS 398 for the {sup 60} Co and the AAPM TG61 for X Rays of 50 and 250 k Vp. Additionally the AAPM protocol TG43 to determine the D{sub w} in function of the kerma intensity S{sub k} in the case of the {sup 137} Cs is used. The calibration curves for the response of the TLD-100 R{sub TLD} vs D{sub w}, corresponding to each one of the sources already mentioned are constructed. The R{sub TLD} vs D{sub w} by least heavy square by means of a second order polynomial that corrects the supralineality of the response is adjusted. The curves are validated by lack of LOF adjustment and by the Anderson Darling normality test. Later the factors of sensitivity (F{sub s}) for the sources of {sup 192} Ir: Micro Selectron and Vari Source are interpolated, used respectively in the A and B hospitals for treatments of brachytherapy of high dose rate (HDR), the expanded uncertainties associated to the D{sub w} and F{sub s} are also determined. Finally, an acrylic phantom and a couple of capsules are already sent to the hospitals mentioned, to verify a nominal D{sub w} of 2 Gy, in a case an underestimate in 5.5% in the imparted D{sub w} and in other an overestimation in a range of -1.5 to -8.0% was obtained. The obtained results in this work establish the bases for the development of a national dosimetric quality control program for brachytherapy of HDR with sources of {sup 192} Ir. (Author)

  13. Generation of high-energy sub-20 fs pulses tunable in the 250-310 nm region by frequency doubling of a high-power noncollinear optical parametric amplifier.

    Science.gov (United States)

    Beutler, Marcus; Ghotbi, Masood; Noack, Frank; Brida, Daniele; Manzoni, Cristian; Cerullo, Giulio

    2009-03-15

    We report on the generation of powerful sub-20 fs deep UV pulses with 10 microJ level energy and broadly tunable in the 250-310 nm range. These pulses are produced by frequency doubling a high-power noncollinear optical parametric amplifier and compressed by a pair of MgF2 prisms to an almost transform-limited duration. Our results provide a power scaling by an order of magnitude with respect to previous works.

  14. Search for Σc → Λcπ using Λc → Σsππ in 250 GeV π--nucleon interactions

    International Nuclear Information System (INIS)

    Passmore, D.A.

    1995-01-01

    Combined cross section times branching fraction limits are given for Σ c ++ → Λ c + π + and Σ c 0 → Λ c + π - where Λ c + → Σ s ± π ± π + . The Λ c + is reconstructed with partial information on the Σ s ; the missing Σ s momentum is established through momentum conservation imposed by a constrained fit. The data are of π - beam interactions at 250 GeV from Fermilab experiment E769

  15. Incidência e principais fatores associados à falha de extubação em recém-nascidos com peso de nascimento < 1.250 gramas Incidence and main risk factors associated with extubation failure in newborns with birth weight < 1,250 grams

    Directory of Open Access Journals (Sweden)

    Fernanda Hermeto

    2009-10-01

    Full Text Available OBJETIVOS: Determinar a incidência de falha de extubação em recém-nascidos prematuros com peso de nascimento OBJECTIVES: To determine the incidence of extubation failure in preterm newborns with birth weight < 1,250 g extubated to nasal continuous positive airway pressure and to identify the main risk factors associated with the need for reintubation in this population. METHODS: A retrospective review of eligible infants admitted and mechanically ventilated between July 2002 and June 2004 was performed. Extubation failure was defined as the need for reintubation within 7 days after the first extubation attempt. RESULTS: Of the 52 patients included in the study, 13 died before the first extubation attempt. Of the remaining 39 patients, only nine failed extubation (23.1% Comparing the two groups (failure vs. successful, there was a statistically significant difference regarding birth weight, gestational age and 5-minute Apgar score. After logistic regression, only gestational age was significant. Other secondary outcomes showed significant difference between the groups: intracranial hemorrhage grade III and/or IV, patent ductus arteriosus and death. CONCLUSIONS: The incidence of extubation failure in our population was similar to the rate reported in the literature. The main risk factor for extubation failure was prematurity (≤ 28 weeks. In this population of extreme preterm infants, implementation of strategies for early extubation, use of methylxanthines, prevention of patent ductus arteriosus, and use of different modes of assisted ventilation after extubation may improve the outcomes.

  16. SU-E-T-359: Emulation of Yb-169 Gamma-Ray Spectrum Using Metal-Filtered 250 KVp X-Rays for Pre-Clinical Studies of Gold Nanoparticle-Aided Radiation Therapy

    International Nuclear Information System (INIS)

    Reynoso, F; Cho, S

    2015-01-01

    Purpose: To develop an external beam surrogate of the Yb-169 brachytherapy source applying a filter-based spectrum modulation technique to 250 kVp x-rays. In-vitro/vivo studies performed with the modulated 250 kVp beam will help gauge the benefits of implementing gold nanoparticle-aided radiotherapy with the Yb-169 source. Methods: A previously validated MCNP5 model of the Phillips RT-250 orthovoltage unit was used to obtain the percentage depth dose (PDD) and filtered photon spectra for a variety of filtration and irradiation conditions. Photon spectra were obtained using the average flux F4 tally in air right after all collimation. A 30 x 30 x 30 cm 3 water phantom was used to compute the PDD along the central axis (CAX) under the standards conditions of a 10 x 10 cm 2 field size at 50 cm SSD. Cylindrical cells of 4 cm in diameter and the energy deposition F6 tally were used along the CAX to score the doses down to 20 cm depth. The number of particle history was set to 2 x 10 8 in order to keep the relative uncertainty within each cell < 0.3%. The secondary electron spectrum within a gold-loaded tissue due to each photon spectrum was also calculated using EGSnrc and compared with that due to Yb-169 gamma rays. Results: Under the practical constraints for the spectrum modulation task, 250 kVp x-rays filtered by a 0.25 mm Erbium (Er) foil produced the best match with Yb-169 gamma rays, in terms of PDD and, more importantly, secondary electron spectrum. Conclusion: Modulation of 250kVp x-ray spectrum by an Er-filter was found effective in emulating the gamma ray spectrum of Yb-169. Possible benefits as predicted from the current MC model such as enhanced radiosensitization with the Er-filtered beam (as a surrogate of Yb-169) was confirmed with a separate in-vitro study. Supported by DOD/PCRP grant W81XWH-12-1-0198

  17. Prospective, randomised trial of the time dependent antiplatelet effects of 500 mg and 250 mg acetylsalicylic acid i. v. and 300 mg p. o. in ACS (ACUTE).

    Science.gov (United States)

    Zeymer, Uwe; Hohlfeld, Thomas; Vom Dahl, Jürgen; Erbel, Raimund; Münzel, Thomas; Zahn, Ralf; Roitenberg, Alexander; Breitenstein, Stefanie; Pap, Ákos Ferenc; Trenk, Dietmar

    2017-02-28

    Little is known about the onset of action after intravenous or oral administration of acetylsalicylic acid (ASA) in patients with acute coronary syndromes (ACS). The aim of the study was to compare intravenous 250 or 500 mg acetylsalicylic acid (ASA) with oral 300 mg in ASA naïve patients with ACS concerning the onset of antiplatelet effects measured by time dependent thromboxane inhibition. A total of 270 patients with ACS acid (AA)-induced platelet thromboxane release (TXB 2 ) 5 minutes (min) after study drug administration. Both 250 mg and 500 mg ASA i. v. inhibited TXB 2 formation nearly completely (geometric means: from 581.7 and 573.9 ng/ml at baseline to 3.9 and 3.1 ng/ml at 5 min, respectively) compared to 300 mg oral ASA (geometric means: from 652.0 to 223.7 ng/ml) (p-value, ANCOVA: < 0.0001). Similar results were obtained for inhibition of AA-induced platelet aggregation (Multiplate ASPItest; from means 86.41 and 85.72 U to 23.04 and 20.57 U at 5 min, respectively) compared to 300 mg oral ASA from mean 87.18 to 75.56 U (p-value, ANCOVA: <0.0001). The rate of bleedings was low and comparable between the groups. In summary, the administration of a single dose of 250 or 500 mg ASA IV compared to 300 mg orally is associated with a faster and more complete inhibition of thromboxane generation and platelet aggregation. Bleeding complications were comparable between the groups.

  18. Pairwise comparison of {sup 89}Zr- and {sup 124}I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Cheal, Sarah M.; Punzalan, Blesida; Doran, Michael G.; Osborne, Joseph R. [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Evans, Michael J. [Memorial Sloan-Kettering Cancer Center, Human Oncology and Pathogenesis Program, New York, NY (United States); Lewis, Jason S. [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Memorial Sloan-Kettering Cancer Center, Program in Molecular Pharmacology and Chemistry, New York, NY (United States); Memorial Sloan-Kettering Cancer Center, Radiochemistry and Imaging Sciences Service, New York, NY (United States); Zanzonico, Pat [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Memorial Sloan-Kettering Cancer Center, Molecular Pharmacology and Therapy Service, New York, NY (United States); Memorial-Sloan Kettering Cancer Center, New York, NY (United States); Larson, Steven M. [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Memorial Sloan-Kettering Cancer Center, Program in Molecular Pharmacology and Chemistry, New York, NY (United States); Memorial Sloan-Kettering Cancer Center, Molecular Pharmacology and Therapy Service, New York, NY (United States)

    2014-05-15

    The PET tracer, {sup 124}I-cG250, directed against carbonic anhydrase IX (CAIX) shows promise for presurgical diagnosis of clear-cell renal cell carcinoma (ccRCC) (Divgi et al. in Lancet Oncol 8:304-310, 2007; Divgi et al. in J Clin Oncol 31:187-194, 2013). The radiometal {sup 89}Zr, however, may offer advantages as a surrogate PET nuclide over {sup 124}I in terms of greater tumor uptake and retention (Rice et al. in Semin Nucl Med 41:265-282, 2011). We have developed a nonlinear immunokinetic model to facilitate a quantitative comparison of absolute uptake and antibody turnover between {sup 124}I-cG250 and {sup 89}Zr-cG250 using a human ccRCC xenograft tumor model in mice. We believe that this unique model better relates quantitative imaging data to the salient biological features of tumor antibody-antigen binding and turnover. We conducted experiments with {sup 89}Zr-cG250 and {sup 124}I-cG250 using a human ccRCC cell line (SK-RC-38) to characterize the binding affinity and internalization kinetics of the two tracers in vitro. Serial PET imaging was performed in mice bearing subcutaneous ccRCC tumors to simultaneously detect and quantify time-dependent tumor uptake in vivo. Using the known specific activities of the two tracers, the equilibrium rates of antibody internalization and turnover in the tumors were derived from the PET images using nonlinear compartmental modeling. The two tracers demonstrated virtually identical tumor cell binding and internalization but showed markedly different retentions in vitro. Superior PET images were obtained using {sup 89}Zr-cG250, owing to the more prolonged trapping of the radiolabel in the tumor and simultaneous washout from normal tissues. Estimates of cG250/CAIX complex turnover were 1.35 - 5.51 x 10{sup 12} molecules per hour per gram of tumor (20 % of receptors internalized per hour), and the ratio of {sup 124}I/{sup 89}Zr atoms released per unit time by tumor was 17.5. Pairwise evaluation of {sup 89}Zr-cG250 and {sup

  19. Idea and implementation studies of populating TOPO250 component with the data from TOPO10 - generalization of geographic information in the BDG database. (Polish Title: Koncepcja i studium implementacji procesu zasilania komponentu TOPO250 danymi TOPO10 - generalizacja informacji geograficznej w bazie danych BDG )

    Science.gov (United States)

    Olszewski, R.; Pillich-Kolipińska, A.; Fiedukowicz, A.

    2013-12-01

    Implementation of INSPIRE Directive in Poland requires not only legal transposition but also development of a number of technological solutions. The one of such tasks, associated with creation of Spatial Information Infrastructure in Poland, is developing a complex model of georeference database. Significant funding for GBDOT project enables development of the national basic topographical database as a multiresolution database (MRDB). Effective implementation of this type of database requires developing procedures for generalization of geographic information (generalization of digital landscape model - DLM), which, treating TOPO10 component as the only source for creation of TOPO250 component, will allow keeping conceptual and classification consistency between those database elements. To carry out this task, the implementation of the system's concept (prepared previously for Head Office of Geodesy and Cartography) is required. Such system is going to execute the generalization process using constrained-based modeling and allows to keep topological relationships between the objects as well as between the object classes. Full implementation of the designed generalization system requires running comprehensive tests which would help with its calibration and parameterization of the generalization procedures (related to the character of generalized area). Parameterization of this process will allow determining the criteria of specific objects selection, simplification algorithms as well as the operation order. Tests with the usage of differentiated, related to the character of the area, generalization process parameters become nowadays the priority issue. Parameters are delivered to the system in the form of XML files, which, with the help of dedicated tool, are generated from the spreadsheet files (XLS) filled in by user. Using XLS file makes entering and modifying the parameters easier. Among the other elements defined by the external parametric files there are

  20. Changes in agricultural cropland areas between a water-surplus year and a water-deficit year impacting food security, determined using MODIS 250 m time-series data and spectral matching techniques, in the Krishna river basin (India)

    Science.gov (United States)

    Gumma, Murali Krishna; Thenkabail, Prasad S.; Muralikrishna, I.V.; Velpuri, Naga Manohar; Gangadhararao, P.T.; Dheeravath, V.; Biradar, C.M.; Nalan, S.A.; Gaur, A.

    2011-01-01

    The objective of this study was to investigate the changes in cropland areas as a result of water availability using Moderate Resolution Imaging Spectroradiometer (MODIS) 250 m time-series data and spectral matching techniques (SMTs). The study was conducted in the Krishna River basin in India, a very large river basin with an area of 265 752 km2 (26 575 200 ha), comparing a water-surplus year (2000–2001) and a water-deficit year (2002–2003). The MODIS 250 m time-series data and SMTs were found ideal for agricultural cropland change detection over large areas and provided fuzzy classification accuracies of 61–100% for various land‐use classes and 61–81% for the rain-fed and irrigated classes. The most mixing change occurred between rain-fed cropland areas and informally irrigated (e.g. groundwater and small reservoir) areas. Hence separation of these two classes was the most difficult. The MODIS 250 m-derived irrigated cropland areas for the districts were highly correlated with the Indian Bureau of Statistics data, with R 2-values between 0.82 and 0.86.The change in the net area irrigated was modest, with an irrigated area of 8 669 881 ha during the water-surplus year, as compared with 7 718 900 ha during the water-deficit year. However, this is quite misleading as most of the major changes occurred in cropping intensity, such as changing from higher intensity to lower intensity (e.g. from double crop to single crop). The changes in cropping intensity of the agricultural cropland areas that took place in the water-deficit year (2002–2003) when compared with the water-surplus year (2000–2001) in the Krishna basin were: (a) 1 078 564 ha changed from double crop to single crop, (b) 1 461 177 ha changed from continuous crop to single crop, (c) 704 172 ha changed from irrigated single crop to fallow and (d) 1 314 522 ha changed from minor irrigation (e.g. tanks, small reservoirs) to rain-fed. These are highly significant changes that will