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Sample records for membrane curvature preference

  1. CURVATURE-DRIVEN MOLECULAR FLOW ON MEMBRANE SURFACE.

    Science.gov (United States)

    Mikucki, Michael; Zhou, Y C

    2017-01-01

    This work presents a mathematical model for the localization of multiple species of diffusion molecules on membrane surfaces. Morphological change of bilayer membrane in vivo is generally modulated by proteins. Most of these modulations are associated with the localization of related proteins in the crowded lipid environments. We start with the energetic description of the distributions of molecules on curved membrane surface, and define the spontaneous curvature of bilayer membrane as a function of the molecule concentrations on membrane surfaces. A drift-diffusion equation governs the gradient flow of the surface molecule concentrations. We recast the energetic formulation and the related governing equations by using an Eulerian phase field description to define membrane morphology. Computational simulations with the proposed mathematical model and related numerical techniques predict (i) the molecular localization on static membrane surfaces at locations with preferred mean curvatures, and (ii) the generation of preferred mean curvature which in turn drives the molecular localization.

  2. Novel tilt-curvature coupling in lipid membranes

    Science.gov (United States)

    Terzi, M. Mert; Deserno, Markus

    2017-08-01

    On mesoscopic scales, lipid membranes are well described by continuum theories whose main ingredients are the curvature of a membrane's reference surface and the tilt of its lipid constituents. In particular, Hamm and Kozlov [Eur. Phys. J. E 3, 323 (2000)] have shown how to systematically derive such a tilt-curvature Hamiltonian based on the elementary assumption of a thin fluid elastic sheet experiencing internal lateral pre-stress. Performing a dimensional reduction, they not only derive the basic form of the effective surface Hamiltonian but also express its emergent elastic couplings as trans-membrane moments of lower-level material parameters. In the present paper, we argue, though, that their derivation unfortunately missed a coupling term between curvature and tilt. This term arises because, as one moves along the membrane, the curvature-induced change of transverse distances contributes to the area strain—an effect that was believed to be small but nevertheless ends up contributing at the same (quadratic) order as all other terms in their Hamiltonian. We illustrate the consequences of this amendment by deriving the monolayer and bilayer Euler-Lagrange equations for the tilt, as well as the power spectra of shape, tilt, and director fluctuations. A particularly curious aspect of our new term is that its associated coupling constant is the second moment of the lipid monolayer's lateral stress profile—which within this framework is equal to the monolayer Gaussian curvature modulus, κ¯ m. On the one hand, this implies that many theoretical predictions now contain a parameter that is poorly known (because the Gauss-Bonnet theorem limits access to the integrated Gaussian curvature); on the other hand, the appearance of κ¯ m outside of its Gaussian curvature provenance opens opportunities for measuring it by more conventional means, for instance by monitoring a membrane's undulation spectrum at short scales.

  3. Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

    DEFF Research Database (Denmark)

    Larsen, Jannik Bruun; Jensen, Martin Borch; Bhatia, Vikram Kjøller

    2015-01-01

    Trafficking and sorting of membrane-anchored Ras GTPases are regulated by partitioning between distinct membrane domains. Here, in vitro experiments and microscopic molecular theory reveal membrane curvature as a new modulator of N-Ras lipid anchor and palmitoyl chain partitioning. Membrane...

  4. Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

    DEFF Research Database (Denmark)

    Boye, Theresa Louise; Maeda, Kenji; Pezeshkian, Weria

    2017-01-01

    Efficient cell membrane repair mechanisms are essential for maintaining membrane integrity and thus for cell life. Here we show that the Ca2+- and phospholipid-binding proteins annexin A4 and A6 are involved in plasma membrane repair and needed for rapid closure of micron-size holes. We demonstrate...... that annexin A4 binds to artificial membranes and generates curvature force initiated from free edges, whereas annexin A6 induces constriction force. In cells, plasma membrane injury and Ca2+ influx recruit annexin A4 to the vicinity of membrane wound edges where its homo-trimerization leads to membrane...... that induction of curvature force around wound edges is an early key event in cell membrane repair....

  5. A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins

    DEFF Research Database (Denmark)

    Bhatia, Vikram Kjøller; Hatzakis, Nikos; Stamou, Dimitrios

    2010-01-01

    itself. We thus anticipate that membrane curvature will promote the redistribution of proteins that are anchored in membranes through any type of hydrophobic moiety, a thesis that broadens tremendously the implications of membrane curvature for protein sorting, trafficking and signaling in cell biology....

  6. Amphipathic motifs in BAR domains are essential for membrane curvature sensing

    DEFF Research Database (Denmark)

    Bhatia, Vikram K; Madsen, Kenneth L; Bolinger, Pierre-Yves

    2009-01-01

    BAR (Bin/Amphiphysin/Rvs) domains and amphipathic alpha-helices (AHs) are believed to be sensors of membrane curvature thus facilitating the assembly of protein complexes on curved membranes. Here, we used quantitative fluorescence microscopy to compare the binding of both motifs on single...... nanosized liposomes of different diameters and therefore membrane curvature. Characterization of members of the three BAR domain families showed surprisingly that the crescent-shaped BAR dimer with its positively charged concave face is not able to sense membrane curvature. Mutagenesis on BAR domains showed...... that membrane curvature sensing critically depends on the N-terminal AH and furthermore that BAR domains sense membrane curvature through hydrophobic insertion in lipid packing defects and not through electrostatics. Consequently, amphipathic motifs, such as AHs, that are often associated with BAR domains...

  7. Protein shape and crowding drive domain formation and curvature in biological membranes

    NARCIS (Netherlands)

    Frese, R.N.; Pamies, Josep C.; Olsen, John D.; Bahatyrova, S.; van der Weij-de Wit, Chantal D.; Aartsma, Thijs J.; Otto, Cornelis; Hunter, C. Neil; Frenkel, Daan; van Grondelle, Rienk

    2007-01-01

    Folding, curvature, and domain formation are characteristics of many biological membranes. Yet the mechanisms that drive both curvature and the formation of specialized domains enriched in particular protein complexes are unknown. For this reason, studies in membranes whose shape and organization

  8. Curvature of double-membrane organelles generated by changes in membrane size and composition.

    Directory of Open Access Journals (Sweden)

    Roland L Knorr

    Full Text Available Transient double-membrane organelles are key players in cellular processes such as autophagy, reproduction, and viral infection. These organelles are formed by the bending and closure of flat, double-membrane sheets. Proteins are believed to be important in these morphological transitions but the underlying mechanism of curvature generation is poorly understood. Here, we describe a novel mechanism for this curvature generation which depends primarily on three membrane properties: the lateral size of the double-membrane sheets, the molecular composition of their highly curved rims, and a possible asymmetry between the two flat faces of the sheets. This mechanism is evolutionary advantageous since it does not require active processes and is readily available even when resources within the cell are restricted as during starvation, which can induce autophagy and sporulation. We identify pathways for protein-assisted regulation of curvature generation, organelle size, direction of bending, and morphology. Our theory also provides a mechanism for the stabilization of large double-membrane sheet-like structures found in the endoplasmic reticulum and in the Golgi cisternae.

  9. Membrane curvature stress and antibacterial activity of lactoferricin derivatives.

    Science.gov (United States)

    Zweytick, Dagmar; Tumer, Sabine; Blondelle, Sylvie E; Lohner, Karl

    2008-05-02

    We have studied correlation of non-lamellar phase formation and antimicrobial activity of two cationic amphipathic peptides, termed VS1-13 and VS1-24 derived from a fragment (LF11) of human lactoferricin on Escherichia coli total lipid extracts. Compared to LF11, VS1-13 exhibits minor, but VS1-24 significantly higher antimicrobial activity. X-ray experiments demonstrated that only VS1-24 decreased the onset of cubic phase formation of dispersions of E. coli lipid extracts, significantly, down to physiological relevant temperatures. Cubic structures were identified to belong to the space groups Pn3m and Im3m. Formation of latter is enhanced in the presence of VS1-24. Additionally, the presence of this peptide caused membrane thinning in the fluid phase, which may promote cubic phase formation. VS1-24 containing a larger hydrophobic volume at the N-terminus than its less active counterpart VS1-13 seems to increase curvature stress in the bilayer and alter the behaviour of the membrane significantly enhancing disruption.

  10. Single Lipid Molecule Dynamics on Supported Lipid Bilayers with Membrane Curvature

    Directory of Open Access Journals (Sweden)

    Philip P. Cheney

    2017-03-01

    Full Text Available The plasma membrane is a highly compartmentalized, dynamic material and this organization is essential for a wide variety of cellular processes. Nanoscale domains allow proteins to organize for cell signaling, endo- and exocytosis, and other essential processes. Even in the absence of proteins, lipids have the ability to organize into domains as a result of a variety of chemical and physical interactions. One feature of membranes that affects lipid domain formation is membrane curvature. To directly test the role of curvature in lipid sorting, we measured the accumulation of two similar lipids, 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine (DHPE and hexadecanoic acid (HDA, using a supported lipid bilayer that was assembled over a nanopatterned surface to obtain regions of membrane curvature. Both lipids studied contain 16 carbon, saturated tails and a head group tag for fluorescence microscopy measurements. The accumulation of lipids at curvatures ranging from 28 nm to 55 nm radii was measured and fluorescein labeled DHPE accumulated more than fluorescein labeled HDA at regions of membrane curvature. We then tested whether single biotinylated DHPE molecules sense curvature using single particle tracking methods. Similar to groups of fluorescein labeled DHPE accumulating at curvature, the dynamics of single molecules of biotinylated DHPE was also affected by membrane curvature and highly confined motion was observed.

  11. Measuring the composition-curvature coupling in binary lipid membranes by computer simulations

    Energy Technology Data Exchange (ETDEWEB)

    Barragán Vidal, I. A., E-mail: vidal@theorie.physik.uni-goettingen.de; Müller, M., E-mail: mmueller@theorie.physik.uni-goettingen.de [Institut für Theoretische Physik, Georg-August-Universität, Friedrich-Hund-Platz 1, 37077 Göttingen (Germany); Rosetti, C. M., E-mail: carla@dqb.fcq.unc.edu.ar [Centro de Investigaciones en Química Biológica de Córdoba, Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, Córdoba (Argentina); Pastorino, C., E-mail: pastor@cnea.gov.ar [Departamento de Física de la Materia Condensada, Centro Atómico Constituyentes, CNEA/CONICET, Av. Gral. Paz 1499, 1650 Pcia. de Buenos Aires (Argentina)

    2014-11-21

    The coupling between local composition fluctuations in binary lipid membranes and curvature affects the lateral membrane structure. We propose an efficient method to compute the composition-curvature coupling in molecular simulations and apply it to two coarse-grained membrane models—a minimal, implicit-solvent model and the MARTINI model. Both the weak-curvature behavior that is typical for thermal fluctuations of planar bilayer membranes as well as the strong-curvature regime corresponding to narrow cylindrical membrane tubes are studied by molecular dynamics simulation. The simulation results are analyzed by using a phenomenological model of the thermodynamics of curved, mixed bilayer membranes that accounts for the change of the monolayer area upon bending. Additionally the role of thermodynamic characteristics such as the incompatibility between the two lipid species and asymmetry of composition are investigated.

  12. Measuring the composition-curvature coupling in binary lipid membranes by computer simulations

    International Nuclear Information System (INIS)

    Barragán Vidal, I. A.; Müller, M.; Rosetti, C. M.; Pastorino, C.

    2014-01-01

    The coupling between local composition fluctuations in binary lipid membranes and curvature affects the lateral membrane structure. We propose an efficient method to compute the composition-curvature coupling in molecular simulations and apply it to two coarse-grained membrane models—a minimal, implicit-solvent model and the MARTINI model. Both the weak-curvature behavior that is typical for thermal fluctuations of planar bilayer membranes as well as the strong-curvature regime corresponding to narrow cylindrical membrane tubes are studied by molecular dynamics simulation. The simulation results are analyzed by using a phenomenological model of the thermodynamics of curved, mixed bilayer membranes that accounts for the change of the monolayer area upon bending. Additionally the role of thermodynamic characteristics such as the incompatibility between the two lipid species and asymmetry of composition are investigated

  13. BAR domains, amphipathic helices and membrane-anchored proteins use the same mechanism to sense membrane curvature

    DEFF Research Database (Denmark)

    Madsen, Kenneth Lindegaard; Bhatia, V K; Gether, U

    2010-01-01

    /ensemble liposome samples of different mean diameter. Next, we describe two different MCS protein motifs (amphipathic helices and BAR domains) and suggest that in both cases curvature sensitive membrane binding results from asymmetric insertion of hydrophobic amino acids in the lipid membrane. This mechanism can...

  14. DNA release from lipoplexes by anionic lipids: correlation with lipid mesomorphism, interfacial curvature, and membrane fusion

    Energy Technology Data Exchange (ETDEWEB)

    Tarahovsky, Yury S.; Koynova, Rumiana; MacDonald, Robert C. (Northwestern)

    2010-01-18

    DNA release from lipoplexes is an essential step during lipofection and is probably a result of charge neutralization by cellular anionic lipids. As a model system to test this possibility, fluorescence resonance energy transfer between DNA and lipid covalently labeled with Cy3 and BODIPY, respectively, was used to monitor the release of DNA from lipid surfaces induced by anionic liposomes. The separation of DNA from lipid measured this way was considerably slower and less complete than that estimated with noncovalently labeled DNA, and depends on the lipid composition of both lipoplexes and anionic liposomes. This result was confirmed by centrifugal separation of released DNA and lipid. X-ray diffraction revealed a clear correlation of the DNA release capacity of the anionic lipids with the interfacial curvature of the mesomorphic structures developed when the anionic and cationic liposomes were mixed. DNA release also correlated with the rate of fusion of anionic liposomes with lipoplexes. It is concluded that the tendency to fuse and the phase preference of the mixed lipid membranes are key factors for the rate and extent of DNA release. The approach presented emphasizes the importance of the lipid composition of both lipoplexes and target membranes and suggests optimal transfection may be obtained by tailoring lipoplex composition to the lipid composition of target cells.

  15. The homeodomain derived peptide Penetratin induces curvature of fluid membrane domains.

    Directory of Open Access Journals (Sweden)

    Antonin Lamazière

    Full Text Available BACKGROUND: Protein membrane transduction domains that are able to cross the plasma membrane are present in several transcription factors, such as the homeodomain proteins and the viral proteins such as Tat of HIV-1. Their discovery resulted in both new concepts on the cell communication during development, and the conception of cell penetrating peptide vectors for internalisation of active molecules into cells. A promising cell penetrating peptide is Penetratin, which crosses the cell membranes by a receptor and metabolic energy-independent mechanism. Recent works have claimed that Penetratin and similar peptides are internalized by endocytosis, but other endocytosis-independent mechanisms have been proposed. Endosomes or plasma membranes crossing mechanisms are not well understood. Previously, we have shown that basic peptides induce membrane invaginations suggesting a new mechanism for uptake, "physical endocytosis". METHODOLOGY/PRINCIPAL FINDINGS: Herein, we investigate the role of membrane lipid phases on Penetratin induced membrane deformations (liquid ordered such as in "raft" microdomains versus disordered fluid "non-raft" domains in membrane models. Experimental data show that zwitterionic lipid headgroups take part in the interaction with Penetratin suggesting that the external leaflet lipids of cells plasma membrane are competent for peptide interaction in the absence of net negative charges. NMR and X-ray diffraction data show that the membrane perturbations (tubulation and vesiculation are associated with an increase in membrane negative curvature. These effects on curvature were observed in the liquid disordered but not in the liquid ordered (raft-like membrane domains. CONCLUSIONS/SIGNIFICANCE: The better understanding of the internalisation mechanisms of protein transduction domains will help both the understanding of the mechanisms of cell communication and the development of potential therapeutic molecular vectors. Here we

  16. The Role of Membrane Curvature in Nanoscale Topography-Induced Intracellular Signaling.

    Science.gov (United States)

    Lou, Hsin-Ya; Zhao, Wenting; Zeng, Yongpeng; Cui, Bianxiao

    2018-05-15

    Over the past decade, there has been growing interest in developing biosensors and devices with nanoscale and vertical topography. Vertical nanostructures induce spontaneous cell engulfment, which enhances the cell-probe coupling efficiency and the sensitivity of biosensors. Although local membranes in contact with the nanostructures are found to be fully fluidic for lipid and membrane protein diffusions, cells appear to actively sense and respond to the surface topography presented by vertical nanostructures. For future development of biodevices, it is important to understand how cells interact with these nanostructures and how their presence modulates cellular function and activities. How cells recognize nanoscale surface topography has been an area of active research for two decades before the recent biosensor works. Extensive studies show that surface topographies in the range of tens to hundreds of nanometers can significantly affect cell functions, behaviors, and ultimately the cell fate. For example, titanium implants having rough surfaces are better for osteoblast attachment and host-implant integration than those with smooth surfaces. At the cellular level, nanoscale surface topography has been shown by a large number of studies to modulate cell attachment, activity, and differentiation. However, a mechanistic understanding of how cells interact and respond to nanoscale topographic features is still lacking. In this Account, we focus on some recent studies that support a new mechanism that local membrane curvature induced by nanoscale topography directly acts as a biochemical signal to induce intracellular signaling, which we refer to as the curvature hypothesis. The curvature hypothesis proposes that some intracellular proteins can recognize membrane curvatures of a certain range at the cell-to-material interface. These proteins then recruit and activate downstream components to modulate cell signaling and behavior. We discuss current technologies

  17. Influence of Global and Local Membrane Curvature on Mechanosensitive Ion Channels: A Finite Element Approach

    Directory of Open Access Journals (Sweden)

    Omid Bavi

    2016-02-01

    Full Text Available Mechanosensitive (MS channels are ubiquitous molecular force sensors that respond to a number of different mechanical stimuli including tensile, compressive and shear stress. MS channels are also proposed to be molecular curvature sensors gating in response to bending in their local environment. One of the main mechanisms to functionally study these channels is the patch clamp technique. However, the patch of membrane surveyed using this methodology is far from physiological. Here we use continuum mechanics to probe the question of how curvature, in a standard patch clamp experiment, at different length scales (global and local affects a model MS channel. Firstly, to increase the accuracy of the Laplace’s equation in tension estimation in a patch membrane and to be able to more precisely describe the transient phenomena happening during patch clamping, we propose a modified Laplace’s equation. Most importantly, we unambiguously show that the global curvature of a patch, which is visible under the microscope during patch clamp experiments, is of negligible energetic consequence for activation of an MS channel in a model membrane. However, the local curvature (RL < 50 and the direction of bending are able to cause considerable changes in the stress distribution through the thickness of the membrane. Not only does local bending, in the order of physiologically relevant curvatures, cause a substantial change in the pressure profile but it also significantly modifies the stress distribution in response to force application. Understanding these stress variations in regions of high local bending is essential for a complete understanding of the effects of curvature on MS channels.

  18. Manipulating lipid membrane architecture by liquid crystal-analog curvature elasticity (Presentation Recording)

    Science.gov (United States)

    Lee, Sin-Doo

    2015-10-01

    Soft matters such as liquid crystals and biological molecules exhibit a variety of interesting physical phenomena as well as new applications. Recently, in mimicking biological systems that have the ability to sense, regulate, grow, react, and regenerate in a highly responsive and self-adaptive manner, the significance of the liquid crystal order in living organisms, for example, a biological membrane possessing the lamellar order, is widely recognized from the viewpoints of physics and chemistry of interfaces and membrane biophysics. Lipid bilayers, resembling cell membranes, provide primary functions for the transport of biological components of ions and molecules in various cellular activities, including vesicle budding and membrane fusion, through lateral organization of the membrane components such as proteins. In this lecture, I will describe how the liquid crystal-analog curvature elasticity of a lipid bilayer plays a critical role in developing a new platform for understanding diverse biological functions at a cellular level. The key concept is to manipulate the local curvature at an interface between a solid substrate and a model membrane. Two representative examples will be demonstrated: one of them is the topographic control of lipid rafts in a combinatorial array where the ligand-receptor binding event occurs and the other concerns the reconstitution of a ring-type lipid raft in bud-mimicking architecture within the framework of the curvature elasticity.

  19. Membrane Stored Curvature Elastic Stress Modulates Recruitment of Maintenance Proteins PspA and Vipp1.

    Science.gov (United States)

    McDonald, Christopher; Jovanovic, Goran; Ces, Oscar; Buck, Martin

    2015-09-01

    Phage shock protein A (PspA), which is responsible for maintaining inner membrane integrity under stress in enterobacteria, and vesicle-inducting protein in plastids 1 (Vipp1), which functions for membrane maintenance and thylakoid biogenesis in cyanobacteria and plants, are similar peripheral membrane-binding proteins. Their homologous N-terminal amphipathic helices are required for membrane binding; however, the membrane features recognized and required for expressing their functionalities have remained largely uncharacterized. Rigorously controlled, in vitro methodologies with lipid vesicles and purified proteins were used in this study and provided the first biochemical and biophysical characterizations of membrane binding by PspA and Vipp1. Both proteins are found to sense stored curvature elastic (SCE) stress and anionic lipids within the membrane. PspA has an enhanced sensitivity for SCE stress and a higher affinity for the membrane than Vipp1. These variations in binding may be crucial for some of the proteins' differing roles in vivo. Assays probing the transcriptional regulatory function of PspA in the presence of vesicles showed that a relief of transcription inhibition occurs in an SCE stress-specific manner. This in vitro recapitulation of membrane stress-dependent transcription control suggests that the Psp response may be mounted in vivo when a cell's inner membrane experiences increased SCE stress. All cell types maintain the integrity of their membrane systems. One widely distributed membrane stress response system in bacteria is the phage shock protein (Psp) system. The central component, peripheral membrane protein PspA, which mitigates inner membrane stress in bacteria, has a counterpart, Vipp1, which functions for membrane maintenance and thylakoid biogenesis in plants and photosynthetic bacteria. Membrane association of both these proteins is accepted as playing a pivotal role in their functions. Here we show that direct membrane binding by

  20. On ripples and rafts: Curvature induced nanoscale structures in lipid membranes

    International Nuclear Information System (INIS)

    Schmid, Friederike; Dolezel, Stefan; Meinhardt, Sebastian; Lenz, Olaf

    2014-01-01

    We develop an elastic theory that predicts the spontaneous formation of nanoscale structures in lipid bilayers which locally phase separate between two phases with different spontaneous monolayer curvature. The theory rationalizes in a unified manner the observation of a variety of nanoscale structures in lipid membranes: Rippled states in one-component membranes, lipid rafts in multicomponent membranes. Furthermore, we report on recent observations of rippled states and rafts in simulations of a simple coarse-grained model for lipid bilayers, which are compatible with experimental observations and with our elastic model

  1. Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins

    Science.gov (United States)

    Ramakrishnan, N.; Sunil Kumar, P. B.; Radhakrishnan, Ravi

    2014-01-01

    Biological membranes constitute boundaries of cells and cell organelles. These membranes are soft fluid interfaces whose thermodynamic states are dictated by bending moduli, induced curvature fields, and thermal fluctuations. Recently, there has been a flood of experimental evidence highlighting active roles for these structures in many cellular processes ranging from trafficking of cargo to cell motility. It is believed that the local membrane curvature, which is continuously altered due to its interactions with myriad proteins and other macromolecules attached to its surface, holds the key to the emergent functionality in these cellular processes. Mechanisms at the atomic scale are dictated by protein-lipid interaction strength, lipid composition, lipid distribution in the vicinity of the protein, shape and amino acid composition of the protein, and its amino acid contents. The specificity of molecular interactions together with the cooperativity of multiple proteins induce and stabilize complex membrane shapes at the mesoscale. These shapes span a wide spectrum ranging from the spherical plasma membrane to the complex cisternae of the Golgi apparatus. Mapping the relation between the protein-induced deformations at the molecular scale and the resulting mesoscale morphologies is key to bridging cellular experiments across the various length scales. In this review, we focus on the theoretical and computational methods used to understand the phenomenology underlying protein-driven membrane remodeling. Interactions at the molecular scale can be computationally probed by all atom and coarse grained molecular dynamics (MD, CGMD), as well as dissipative particle dynamics (DPD) simulations, which we only describe in passing. We choose to focus on several continuum approaches extending the Canham - Helfrich elastic energy model for membranes to include the effect of curvature-inducing proteins and explore the conformational phase space of such systems. In this

  2. Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins

    Energy Technology Data Exchange (ETDEWEB)

    Ramakrishnan, N., E-mail: ramn@seas.upenn.edu [Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA-19104 (United States); Department of Bioengineering, University of Pennsylvania, Philadelphia, PA-19104 (United States); Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA-19104 (United States); Sunil Kumar, P.B., E-mail: sunil@physics.iitm.ac.in [Department of Physics, Indian Institute of Technology Madras, Chennai, 600036 (India); Radhakrishnan, Ravi, E-mail: rradhak@seas.upenn.edu [Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA-19104 (United States); Department of Bioengineering, University of Pennsylvania, Philadelphia, PA-19104 (United States); Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA-19104 (United States)

    2014-10-01

    Biological membranes constitute boundaries of cells and cell organelles. These membranes are soft fluid interfaces whose thermodynamic states are dictated by bending moduli, induced curvature fields, and thermal fluctuations. Recently, there has been a flood of experimental evidence highlighting active roles for these structures in many cellular processes ranging from trafficking of cargo to cell motility. It is believed that the local membrane curvature, which is continuously altered due to its interactions with myriad proteins and other macromolecules attached to its surface, holds the key to the emergent functionality in these cellular processes. Mechanisms at the atomic scale are dictated by protein–lipid interaction strength, lipid composition, lipid distribution in the vicinity of the protein, shape and amino acid composition of the protein, and its amino acid contents. The specificity of molecular interactions together with the cooperativity of multiple proteins induce and stabilize complex membrane shapes at the mesoscale. These shapes span a wide spectrum ranging from the spherical plasma membrane to the complex cisternae of the Golgi apparatus. Mapping the relation between the protein-induced deformations at the molecular scale and the resulting mesoscale morphologies is key to bridging cellular experiments across various length scales. In this review, we focus on the theoretical and computational methods used to understand the phenomenology underlying protein-driven membrane remodeling. Interactions at the molecular scale can be computationally probed by all atom and coarse grained molecular dynamics (MD, CGMD), as well as dissipative particle dynamics (DPD) simulations, which we only describe in passing. We choose to focus on several continuum approaches extending the Canham–Helfrich elastic energy model for membranes to include the effect of curvature-inducing proteins and explore the conformational phase space of such systems. In this description

  3. Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins

    International Nuclear Information System (INIS)

    Ramakrishnan, N.; Sunil Kumar, P.B.; Radhakrishnan, Ravi

    2014-01-01

    Biological membranes constitute boundaries of cells and cell organelles. These membranes are soft fluid interfaces whose thermodynamic states are dictated by bending moduli, induced curvature fields, and thermal fluctuations. Recently, there has been a flood of experimental evidence highlighting active roles for these structures in many cellular processes ranging from trafficking of cargo to cell motility. It is believed that the local membrane curvature, which is continuously altered due to its interactions with myriad proteins and other macromolecules attached to its surface, holds the key to the emergent functionality in these cellular processes. Mechanisms at the atomic scale are dictated by protein–lipid interaction strength, lipid composition, lipid distribution in the vicinity of the protein, shape and amino acid composition of the protein, and its amino acid contents. The specificity of molecular interactions together with the cooperativity of multiple proteins induce and stabilize complex membrane shapes at the mesoscale. These shapes span a wide spectrum ranging from the spherical plasma membrane to the complex cisternae of the Golgi apparatus. Mapping the relation between the protein-induced deformations at the molecular scale and the resulting mesoscale morphologies is key to bridging cellular experiments across various length scales. In this review, we focus on the theoretical and computational methods used to understand the phenomenology underlying protein-driven membrane remodeling. Interactions at the molecular scale can be computationally probed by all atom and coarse grained molecular dynamics (MD, CGMD), as well as dissipative particle dynamics (DPD) simulations, which we only describe in passing. We choose to focus on several continuum approaches extending the Canham–Helfrich elastic energy model for membranes to include the effect of curvature-inducing proteins and explore the conformational phase space of such systems. In this description

  4. Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins.

    Science.gov (United States)

    Ramakrishnan, N; Sunil Kumar, P B; Radhakrishnan, Ravi

    2014-10-01

    Biological membranes constitute boundaries of cells and cell organelles. These membranes are soft fluid interfaces whose thermodynamic states are dictated by bending moduli, induced curvature fields, and thermal fluctuations. Recently, there has been a flood of experimental evidence highlighting active roles for these structures in many cellular processes ranging from trafficking of cargo to cell motility. It is believed that the local membrane curvature, which is continuously altered due to its interactions with myriad proteins and other macromolecules attached to its surface, holds the key to the emergent functionality in these cellular processes. Mechanisms at the atomic scale are dictated by protein-lipid interaction strength, lipid composition, lipid distribution in the vicinity of the protein, shape and amino acid composition of the protein, and its amino acid contents. The specificity of molecular interactions together with the cooperativity of multiple proteins induce and stabilize complex membrane shapes at the mesoscale. These shapes span a wide spectrum ranging from the spherical plasma membrane to the complex cisternae of the Golgi apparatus. Mapping the relation between the protein-induced deformations at the molecular scale and the resulting mesoscale morphologies is key to bridging cellular experiments across the various length scales. In this review, we focus on the theoretical and computational methods used to understand the phenomenology underlying protein-driven membrane remodeling. Interactions at the molecular scale can be computationally probed by all atom and coarse grained molecular dynamics (MD, CGMD), as well as dissipative particle dynamics (DPD) simulations, which we only describe in passing. We choose to focus on several continuum approaches extending the Canham - Helfrich elastic energy model for membranes to include the effect of curvature-inducing proteins and explore the conformational phase space of such systems. In this

  5. Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

    Science.gov (United States)

    Smith, Alyson S; Nowak, Roberta B; Zhou, Sitong; Giannetto, Michael; Gokhin, David S; Papoin, Julien; Ghiran, Ionita C; Blanc, Lionel; Wan, Jiandi; Fowler, Velia M

    2018-05-08

    The biconcave disk shape and deformability of mammalian RBCs rely on the membrane skeleton, a viscoelastic network of short, membrane-associated actin filaments (F-actin) cross-linked by long, flexible spectrin tetramers. Nonmuscle myosin II (NMII) motors exert force on diverse F-actin networks to control cell shapes, but a function for NMII contractility in the 2D spectrin-F-actin network of RBCs has not been tested. Here, we show that RBCs contain membrane skeleton-associated NMIIA puncta, identified as bipolar filaments by superresolution fluorescence microscopy. MgATP disrupts NMIIA association with the membrane skeleton, consistent with NMIIA motor domains binding to membrane skeleton F-actin and contributing to membrane mechanical properties. In addition, the phosphorylation of the RBC NMIIA heavy and light chains in vivo indicates active regulation of NMIIA motor activity and filament assembly, while reduced heavy chain phosphorylation of membrane skeleton-associated NMIIA indicates assembly of stable filaments at the membrane. Treatment of RBCs with blebbistatin, an inhibitor of NMII motor activity, decreases the number of NMIIA filaments associated with the membrane and enhances local, nanoscale membrane oscillations, suggesting decreased membrane tension. Blebbistatin-treated RBCs also exhibit elongated shapes, loss of membrane curvature, and enhanced deformability, indicating a role for NMIIA contractility in promoting membrane stiffness and maintaining RBC biconcave disk cell shape. As structures similar to the RBC membrane skeleton exist in many metazoan cell types, these data demonstrate a general function for NMII in controlling specialized membrane morphology and mechanical properties through contractile interactions with short F-actin in spectrin-F-actin networks.

  6. Towards understanding of Nipah virus attachment protein assembly and the role of protein affinity and crowding for membrane curvature events.

    Energy Technology Data Exchange (ETDEWEB)

    Stachowiak, Jeanne C.; Hayden, Carl C.; Negrete, Oscar.; Davis, Ryan Wesley; Sasaki, Darryl Y

    2013-10-01

    Pathogenic viruses are a primary threat to our national security and to the health and economy of our world. Effective defense strategies to combat viral infection and spread require the development of understanding of the mechanisms that these pathogens use to invade the host cell. We present in this report results of our research into viral particle recognition and fusion to cell membranes and the role that protein affinity and confinement in lipid domains plays in membrane curvature in cellular fusion and fission events. Herein, we describe 1) the assembly of the G attachment protein of Nipah virus using point mutation studies to define its role in viral particle fusion to the cell membrane, 2) how lateral pressure of membrane bound proteins induce curvature in model membrane systems, and 3) the role of membrane curvature in the selective partitioning of molecular receptors and specific affinity of associated proteins.

  7. Lipid clustering correlates with membrane curvature as revealed by molecular simulations of complex lipid bilayers.

    Directory of Open Access Journals (Sweden)

    Heidi Koldsø

    2014-10-01

    Full Text Available Cell membranes are complex multicomponent systems, which are highly heterogeneous in the lipid distribution and composition. To date, most molecular simulations have focussed on relatively simple lipid compositions, helping to inform our understanding of in vitro experimental studies. Here we describe on simulations of complex asymmetric plasma membrane model, which contains seven different lipids species including the glycolipid GM3 in the outer leaflet and the anionic lipid, phosphatidylinositol 4,5-bisphophate (PIP2, in the inner leaflet. Plasma membrane models consisting of 1500 lipids and resembling the in vivo composition were constructed and simulations were run for 5 µs. In these simulations the most striking feature was the formation of nano-clusters of GM3 within the outer leaflet. In simulations of protein interactions within a plasma membrane model, GM3, PIP2, and cholesterol all formed favorable interactions with the model α-helical protein. A larger scale simulation of a model plasma membrane containing 6000 lipid molecules revealed correlations between curvature of the bilayer surface and clustering of lipid molecules. In particular, the concave (when viewed from the extracellular side regions of the bilayer surface were locally enriched in GM3. In summary, these simulations explore the nanoscale dynamics of model bilayers which mimic the in vivo lipid composition of mammalian plasma membranes, revealing emergent nanoscale membrane organization which may be coupled both to fluctuations in local membrane geometry and to interactions with proteins.

  8. NMR Determination of Protein Partitioning into Membrane Domains with Different Curvatures and Application to the Influenza M2 Peptide

    Science.gov (United States)

    Wang, Tuo; Cady, Sarah D.; Hong, Mei

    2012-01-01

    The M2 protein of the influenza A virus acts both as a drug-sensitive proton channel and mediates virus budding through membrane scission. The segment responsible for causing membrane curvature is an amphipathic helix in the cytoplasmic domain of the protein. Here, we use 31P and 13C solid-state NMR to examine M2-induced membrane curvature. M2(22–46), which includes only the transmembrane (TM) helix, and M2(21–61), which contains an additional amphipathic helix, are studied. 31P chemical shift lineshapes indicate that M2(21–61) causes a high-curvature isotropic phase to both cholesterol-rich virus-mimetic membranes and 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayers, whereas M2(22–46) has minimal effect. The lamellar and isotropic domains have distinct 31P isotropic chemical shifts, indicating perturbation of the lipid headgroup conformation by the amphipathic helix. 31P- and 13C-detected 1H T2 relaxation and two-dimensional peptide-lipid correlation spectra show that M2(21–61) preferentially binds to the high-curvature domain. 31P linewidths indicate that the isotropic vesicles induced by M2(21–61) are 10–35 nm in diameter, and the virus-mimetic vesicles are smaller than the 1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicles. A strong correlation is found between high membrane curvature and weak drug-binding ability of the TM helix. Thus, the M2 amphipathic helix causes membrane curvature, which in turn perturbs the TM helix conformation, abolishing drug binding. These NMR experiments are applicable to other curvature-inducing membrane proteins such as fusion proteins and antimicrobial peptides. PMID:22385849

  9. The effect of curvature on the undulation spectrum of Red Blood Cell membranes

    Science.gov (United States)

    Kuriabova, Tatiana; Henle, Mark L.; Levine, Alex J.

    2009-03-01

    The human red blood cell (RBC) membrane has a composite structure of a fluid lipid bilayer tethered to an elastic 2D spectrin network. The study of the mechanical properties of RBCs is crucial to our understanding of their ability withstand large amplitude deformations during their passage through the microvasculature. The linear mechanical response of this composite membrane can be measured by observing its undulatory dynamics in thermal equilibrium, i.e. microrheology. Previous models of these dynamics postulated an effective surface tension. In this talk, we show that surface tension is not necessary. Rather, the coupling of membrane bending to spectrin network compression by curvature can account for the observed dynamics. We use a simplified theoretical model to describe the undulatory dynamics of RBCs, measured experimentally by the Popescu group.ootnotetextG. Popescu et al. ``Imaging red blood cell dynamics by quantitative phase microscopy, Blood Cells, Molecules, and Diseases, (2008), in print'' Analyzing their data using our model, we observe dramatic changes in RBC membrane elasticity associated with cells' morphological transition from discocytes to echinocyte to spherocyte.

  10. The N-terminal amphipathic helix of the topological specificity factor MinE is associated with shaping membrane curvature.

    Directory of Open Access Journals (Sweden)

    Yu-Ling Shih

    Full Text Available Pole-to-pole oscillations of the Min proteins in Escherichia coli are required for the proper placement of the division septum. Direct interaction of MinE with the cell membrane is critical for the dynamic behavior of the Min system. In vitro, this MinE-membrane interaction led to membrane deformation; however, the underlying mechanism remained unclear. Here we report that MinE-induced membrane deformation involves the formation of an amphipathic helix of MinE(2-9, which, together with the adjacent basic residues, function as membrane anchors. Biochemical evidence suggested that the membrane association induces formation of the helix, with the helical face, consisting of A2, L3, and F6, inserted into the membrane. Insertion of this helix into the cell membrane can influence local membrane curvature and lead to drastic changes in membrane topology. Accordingly, MinE showed characteristic features of protein-induced membrane tubulation and lipid clustering in in vitro reconstituted systems. In conclusion, MinE shares common protein signatures with a group of membrane trafficking proteins in eukaryotic cells. These MinE signatures appear to affect membrane curvature.

  11. MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

    Science.gov (United States)

    Szwedziak, Piotr; Wong, Felix; Schaefer, Kaitlin; Izoré, Thierry; Renner, Lars D; Holmes, Matthew J; Sun, Yingjie; Bisson-Filho, Alexandre W; Walker, Suzanne; Amir, Ariel; Löwe, Jan

    2018-01-01

    MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments move around the rod circumference, helping to insert cell wall in the radial direction to reinforce rod shape. To understand how oriented MreB motion arises, we altered the shape of Bacillus subtilis. MreB motion is isotropic in round cells, and orientation is restored when rod shape is externally imposed. Stationary filaments orient within protoplasts, and purified MreB tubulates liposomes in vitro, orienting within tubes. Together, this demonstrates MreB orients along the greatest principal membrane curvature, a conclusion supported with biophysical modeling. We observed that spherical cells regenerate into rods in a local, self-reinforcing manner: rapidly propagating rods emerge from small bulges, exhibiting oriented MreB motion. We propose that the coupling of MreB filament alignment to shape-reinforcing peptidoglycan synthesis creates a locally-acting, self-organizing mechanism allowing the rapid establishment and stable maintenance of emergent rod shape. PMID:29469806

  12. An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1.

    Science.gov (United States)

    Herlo, Rasmus; Lund, Viktor K; Lycas, Matthew D; Jansen, Anna M; Khelashvili, George; Andersen, Rita C; Bhatia, Vikram; Pedersen, Thomas S; Albornoz, Pedro B C; Johner, Niklaus; Ammendrup-Johnsen, Ina; Christensen, Nikolaj R; Erlendsson, Simon; Stoklund, Mikkel; Larsen, Jannik B; Weinstein, Harel; Kjærulff, Ole; Stamou, Dimitrios; Gether, Ulrik; Madsen, Kenneth L

    2018-05-15

    BAR domains are dimeric protein modules that sense, induce, and stabilize lipid membrane curvature. Here, we show that membrane curvature sensing (MCS) directs cellular localization and function of the BAR domain protein PICK1. In PICK1, and the homologous proteins ICA69 and arfaptin2, we identify an amphipathic helix N-terminal to the BAR domain that mediates MCS. Mutational disruption of the helix in PICK1 impaired MCS without affecting membrane binding per se. In insulin-producing INS-1E cells, super-resolution microscopy revealed that disruption of the helix selectively compromised PICK1 density on insulin granules of high curvature during their maturation. This was accompanied by reduced hormone storage in the INS-1E cells. In Drosophila, disruption of the helix compromised growth regulation. By demonstrating size-dependent binding on insulin granules, our finding highlights the function of MCS for BAR domain proteins in a biological context distinct from their function, e.g., at the plasma membrane during endocytosis. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  13. A Theoretical Characterization of Curvature Controlled Adhesive Properties of Bio-Inspired Membranes

    DEFF Research Database (Denmark)

    Afferante, Luciano; Heepe, Lars; Casdorff, Kirstin

    2016-01-01

    Some biological systems, such as the tree frog, Litoria caerulea, and the bush-cricket, Tettigonia viridissima, have developed the ability to control adhesion by changing the curvature of their pads. Active control systems of adhesion inspired by these biological models can be very attractive...

  14. Salt Bridge Formation between the I-BAR Domain and Lipids Increases Lipid Density and Membrane Curvature.

    Science.gov (United States)

    Takemura, Kazuhiro; Hanawa-Suetsugu, Kyoko; Suetsugu, Shiro; Kitao, Akio

    2017-07-28

    The BAR domain superfamily proteins sense or induce curvature in membranes. The inverse-BAR domain (I-BAR) is a BAR domain that forms a straight "zeppelin-shaped" dimer. The mechanisms by which IRSp53 I-BAR binds to and deforms a lipid membrane are investigated here by all-atom molecular dynamics simulation (MD), binding energy analysis, and the effects of mutation experiments on filopodia on HeLa cells. I-BAR adopts a curved structure when crystallized, but adopts a flatter shape in MD. The binding of I-BAR to membrane was stabilized by ~30 salt bridges, consistent with experiments showing that point mutations of the interface residues have little effect on the binding affinity whereas multiple mutations have considerable effect. Salt bridge formation increases the local density of lipids and deforms the membrane into a concave shape. In addition, the point mutations that break key intra-molecular salt bridges within I-BAR reduce the binding affinity; this was confirmed by expressing these mutants in HeLa cells and observing their effects. The results indicate that the stiffness of I-BAR is important for membrane deformation, although I-BAR does not act as a completely rigid template.

  15. 2,2'-Bis(monoacylglycero) PO4 (BMP), but Not 3,1'-BMP, increases membrane curvature stress to enhance α-tocopherol transfer protein binding to membranes.

    Science.gov (United States)

    Baptist, Matilda; Panagabko, Candace; Nickels, Jonathan D; Katsaras, John; Atkinson, Jeffrey

    2015-03-01

    Previous work revealed that α-tocopherol transfer protein (α-TTP) co-localizes with bis(monoacylglycero)phosphate (BMP) in late endosomes. BMP is a lipid unique to late endosomes and is believed to induce membrane curvature and support the multivesicular nature of this organelle. We examined the effect of BMP on α-TTP binding to membranes using dual polarization interferometry and vesicle-binding assay. α-TTP binding to membranes is increased by the curvature-inducing lipid BMP. α-TTP binds to membranes with greater affinity when they contain the 2,2'-BMP versus 3,1'-BMP isomers.

  16. Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress

    International Nuclear Information System (INIS)

    Rand, R.P.; Fuller, N.L.; Gruner, S.M.; Parsegian, V.A.

    1990-01-01

    Amphiphiles respond both to polar and to nonpolar solvents. In this paper X-ray diffraction and osmotic stress have been used to examine the phase behavior, the structural dimensions, and the work of deforming the monolayer-lined aqueous cavities formed by mixtures of dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC) as a function of the concentration of two solvents, water and tetradecane (td). In the absence of td, most PE/PC mixtures show only lamellar phases in excess water; all of these become single reverse hexagonal (H II ) phases with addition of excess td. The spontaneous radius of curvature R 0 of lipid monolayers, as expressed in these H II phases, is allowed by the relief of hydrocarbon chain stress by td; R 0 increases with the ratio DOPC/DOPE. Single H II phases stressed by limited water or td show several responses. (a) the molecular area is compressed at the polar end of the molecule and expanded at the hydrocarbon ends. (b) For circularly symmetrical water cylinders, the degrees of hydrocarbon chain splaying and polar group compression are different for molecules aligned in different directions around the water cylinder. (c) A pivotal position exists along the length of the phospholipid molecule where little area change occurs as the monolayer is bent to increasing curvatures. (d) By defining R 0 at the pivotal position, the authors find that measured energies are well fit by a quadratic bending energy. (e) For lipid mixtures, enforced deviation of the H II monolayer from R 0 is sufficiently powerful to cause demixing of the phospholipids in a way suggesting that the DOPE/DOPC ratio self-adjusts so that its R 0 matches the amount of td or water available, i.e., that curvature energy is minimized

  17. Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment

    DEFF Research Database (Denmark)

    Larsen, Jannik B.; Kennard, Celeste; Pedersen, Søren L.

    2017-01-01

    Proteins anchored to membranes through covalently linked fatty acids and/or isoprenoid groups play crucial roles in all forms of life. Sorting and trafficking of lipidated proteins has traditionally been discussed in the context of partitioning to membrane domains of different lipid composition. We...

  18. Membrane Curvature Induced by Aggregates of LH2s and Monomeric LH1s

    OpenAIRE

    Chandler, Danielle E.; Gumbart, James; Stack, John D.; Chipot, Christophe; Schulten, Klaus

    2009-01-01

    The photosynthetic apparatus of purple bacteria is contained within organelles called chromatophores, which form as extensions of the cytoplasmic membrane. The shape of these chromatophores can be spherical (as in Rhodobacter sphaeroides), lamellar (as in Rhodopseudomonas acidophila and Phaeospirillum molischianum), or tubular (as in certain Rb. sphaeroides mutants). Chromatophore shape is thought to be influenced by the integral membrane proteins Light Harvesting Complexes I and II (LH1 and ...

  19. Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins

    DEFF Research Database (Denmark)

    Varkey, Jobin; Isas, Jose Mario; Mizuno, Naoko

    2010-01-01

    Synucleins and apolipoproteins have been implicated in a number of membrane and lipid trafficking events. Lipid interaction for both types of proteins is mediated by 11 amino acid repeats that form amphipathic helices. This similarity suggests that synucleins and apolipoproteins might have...... of amphipathic helices alone. Moreover, we frequently observed that a-synuclein caused membrane structures that had the appearance of nascent budding vesicles. The ability to function as a minimal machinery for vesicle budding agrees well with recent findings that a-synuclein plays a role in vesicle trafficking...

  20. Effects of membrane curvature and pH on proton pumping activity of single cytochrome bo3 enzymes

    DEFF Research Database (Denmark)

    Li, Mengqiu; Khan, Sanobar; Rong, Honglin

    2017-01-01

    The molecular mechanism of proton pumping by heme-copper oxidases (HCO) has intrigued the scientific community since it was first proposed. We have recently reported a novel technology that enables the continuous characterisation of proton transport activity of a HCO and ubiquinol oxidase from...... Escherichia coli, cytochrome bo3, for hundreds of seconds on the single enzyme level (Li et al. J Am Chem Soc 137 (2015) 16055–16063). Here, we have extended these studies by additional experiments and analyses of the proton transfer rate as a function of proteoliposome size and pH at the N- and P......-side of single HCOs. Proton transport activity of cytochrome bo3 was found to decrease with increased curvature of the membrane. Furthermore, proton uptake at the N-side (proton entrance) was insensitive to pH between pH 6.4–8.4, while proton release at the P-side had an optimum pH of ~ 7.4, suggesting...

  1. Sequence and conformational preferences at termini of α-helices in membrane proteins: role of the helix environment.

    Science.gov (United States)

    Shelar, Ashish; Bansal, Manju

    2014-12-01

    α-Helices are amongst the most common secondary structural elements seen in membrane proteins and are packed in the form of helix bundles. These α-helices encounter varying external environments (hydrophobic, hydrophilic) that may influence the sequence preferences at their N and C-termini. The role of the external environment in stabilization of the helix termini in membrane proteins is still unknown. Here we analyze α-helices in a high-resolution dataset of integral α-helical membrane proteins and establish that their sequence and conformational preferences differ from those in globular proteins. We specifically examine these preferences at the N and C-termini in helices initiating/terminating inside the membrane core as well as in linkers connecting these transmembrane helices. We find that the sequence preferences and structural motifs at capping (Ncap and Ccap) and near-helical (N' and C') positions are influenced by a combination of features including the membrane environment and the innate helix initiation and termination property of residues forming structural motifs. We also find that a large number of helix termini which do not form any particular capping motif are stabilized by formation of hydrogen bonds and hydrophobic interactions contributed from the neighboring helices in the membrane protein. We further validate the sequence preferences obtained from our analysis with data from an ultradeep sequencing study that identifies evolutionarily conserved amino acids in the rat neurotensin receptor. The results from our analysis provide insights for the secondary structure prediction, modeling and design of membrane proteins. © 2014 Wiley Periodicals, Inc.

  2. Membrane dynamics

    DEFF Research Database (Denmark)

    Bendix, Pól Martin

    2015-01-01

    Current topics include membrane-protein interactions with regard to membrane deformation or curvature sensing by BAR domains. Also, we study the dynamics of membrane tubes of both cells and simple model membrane tubes. Finally, we study membrane phase behavior which has important implications...... for the lateral organization of membranes as wells as for physical properties like bending, permeability and elasticity...

  3. Cholera toxin B subunit induces local curvature on lipid bilayers

    DEFF Research Database (Denmark)

    Pezeshkian, Weria; Nåbo, Lina J.; Ipsen, John H.

    2017-01-01

    B induces a local membrane curvature that is essential for its clathrin-independent uptake. Using all-atom molecular dynamics, we show that CTxB induces local curvature, with the radius of curvature around 36 nm. The main feature of the CTxB molecular structure that causes membrane bending is the protruding...... alpha helices in the middle of the protein. Our study points to a generic protein design principle for generating local membrane curvature through specific binding to their lipid anchors....

  4. The curvature coordinate system

    DEFF Research Database (Denmark)

    Almegaard, Henrik

    2007-01-01

    The paper describes a concept for a curvature coordinate system on regular curved surfaces from which faceted surfaces with plane quadrangular facets can be designed. The lines of curvature are used as parametric lines for the curvature coordinate system on the surface. A new conjugate set of lin...

  5. The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.

    Science.gov (United States)

    Sun, Haiyan; Greathouse, Denise V; Andersen, Olaf S; Koeppe, Roger E

    2008-08-08

    To better understand the structural and functional roles of tryptophan at the membrane/water interface in membrane proteins, we examined the structural and functional consequences of Trp --> 1-methyl-tryptophan substitutions in membrane-spanning gramicidin A channels. Gramicidin A channels are miniproteins that are anchored to the interface by four Trps near the C terminus of each subunit in a membrane-spanning dimer. We masked the hydrogen bonding ability of individual or multiple Trps by 1-methylation of the indole ring and examined the structural and functional changes using circular dichroism spectroscopy, size exclusion chromatography, solid state (2)H NMR spectroscopy, and single channel analysis. N-Methylation causes distinct changes in the subunit conformational preference, channel-forming propensity, single channel conductance and lifetime, and average indole ring orientations within the membrane-spanning channels. The extent of the local ring dynamic wobble does not increase, and may decrease slightly, when the indole NH is replaced by the non-hydrogen-bonding and more bulky and hydrophobic N-CH(3) group. The changes in conformational preference, which are associated with a shift in the distribution of the aromatic residues across the bilayer, are similar to those observed previously with Trp --> Phe substitutions. We conclude that indole N-H hydrogen bonding is of major importance for the folding of gramicidin channels. The changes in ion permeability, however, are quite different for Trp --> Phe and Trp --> 1-methyl-tryptophan substitutions, indicating that the indole dipole moment and perhaps also ring size and are important for ion permeation through these channels.

  6. Curvature-Induced Instabilities of Shells

    Science.gov (United States)

    Pezzulla, Matteo; Stoop, Norbert; Steranka, Mark P.; Bade, Abdikhalaq J.; Holmes, Douglas P.

    2018-01-01

    Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of spontaneous curvature and geometric frustration in curved shells remains poorly understood. Via a combination of precision experiments on elastomeric spherical shells, simulations, and theory, we show how a spontaneous curvature induces a rotational symmetry-breaking buckling as well as a snapping instability reminiscent of the Venus fly trap closure mechanism. The instabilities, and their dependence on geometry, are rationalized by reducing the spontaneous curvature to an effective mechanical load. This formulation reveals a combined pressurelike term in the bulk and a torquelike term in the boundary, allowing scaling predictions for the instabilities that are in excellent agreement with experiments and simulations. Moreover, the effective pressure analogy suggests a curvature-induced subcritical buckling in closed shells. We determine the critical buckling curvature via a linear stability analysis that accounts for the combination of residual membrane and bending stresses. The prominent role of geometry in our findings suggests the applicability of the results over a wide range of scales.

  7. Implementing quantum Ricci curvature

    Science.gov (United States)

    Klitgaard, N.; Loll, R.

    2018-05-01

    Quantum Ricci curvature has been introduced recently as a new, geometric observable characterizing the curvature properties of metric spaces, without the need for a smooth structure. Besides coordinate invariance, its key features are scalability, computability, and robustness. We demonstrate that these properties continue to hold in the context of nonperturbative quantum gravity, by evaluating the quantum Ricci curvature numerically in two-dimensional Euclidean quantum gravity, defined in terms of dynamical triangulations. Despite the well-known, highly nonclassical properties of the underlying quantum geometry, its Ricci curvature can be matched well to that of a five-dimensional round sphere.

  8. Curvature constraints from the causal entropic principle

    International Nuclear Information System (INIS)

    Bozek, Brandon; Albrecht, Andreas; Phillips, Daniel

    2009-01-01

    Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The causal entropic principle (Bousso et al.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the causal entropic principle to predict the preferred curvature within the 'multiverse'. We have found that values larger than ρ k =40ρ m are disfavored by more than 99.99% peak value at ρ Λ =7.9x10 -123 and ρ k =4.3ρ m for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending on the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.

  9. Introducing quantum Ricci curvature

    Science.gov (United States)

    Klitgaard, N.; Loll, R.

    2018-02-01

    Motivated by the search for geometric observables in nonperturbative quantum gravity, we define a notion of coarse-grained Ricci curvature. It is based on a particular way of extracting the local Ricci curvature of a smooth Riemannian manifold by comparing the distance between pairs of spheres with that of their centers. The quantum Ricci curvature is designed for use on non-smooth and discrete metric spaces, and to satisfy the key criteria of scalability and computability. We test the prescription on a variety of regular and random piecewise flat spaces, mostly in two dimensions. This enables us to quantify its behavior for short lattices distances and compare its large-scale behavior with that of constantly curved model spaces. On the triangulated spaces considered, the quantum Ricci curvature has good averaging properties and reproduces classical characteristics on scales large compared to the discretization scale.

  10. Quantifying the Relationship Between Curvature and Electric Potential in Lipid Bilayers

    DEFF Research Database (Denmark)

    Bruhn, Dennis Skjøth; Lomholt, Michael Andersen; Khandelia, Himanshu

    2016-01-01

    Cellular membranes mediate vital cellular processes by being subject to curvature and transmembrane electrical potentials. Here we build upon the existing theory for flexoelectricity in liquid crystals to quantify the coupling between lipid bilayer curvature and membrane potentials. Using molecular...... dynamics simulations, we show that head group dipole moments, the lateral pressure profile across the bilayer and spontaneous curvature all systematically change with increasing membrane potentials. In particu- lar, there is a linear dependence between the bending moment (the product of bending rigidity...

  11. Modeling curvature-dependent subcellular localization of a small sporulation protein in Bacillus subtilis

    Science.gov (United States)

    Wasnik, Vaibhav; Wingreen, Ned; Mukhopadhyay, Ranjan

    2012-02-01

    Recent experiments suggest that in the bacterium, B. subtilis, the cue for the localization of small sporulation protein, SpoVM, that plays a central role in spore coat formation, is curvature of the bacterial plasma membrane. This curvature-dependent localization is puzzling given the orders of magnitude difference in lengthscale of an individual protein and radius of curvature of the membrane. Here we develop a minimal model to study the relationship between curvature-dependent membrane absorption of SpoVM and clustering of membrane-associated SpoVM and compare our results with experiments.

  12. Advanced Curvature Deformable Mirrors

    Science.gov (United States)

    2010-09-01

    ORGANIZATION NAME(S) AND ADDRESS(ES) University of Hawaii ,Institute for Astronomy,640 North A‘ohoku Place, #209 , Hilo ,HI,96720-2700 8. PERFORMING...Advanced Curvature Deformable Mirrors Christ Ftaclas1,2, Aglae Kellerer2 and Mark Chun2 Institute for Astronomy, University of Hawaii

  13. Regularized strings with extrinsic curvature

    International Nuclear Information System (INIS)

    Ambjoern, J.; Durhuus, B.

    1987-07-01

    We analyze models of discretized string theories, where the path integral over world sheet variables is regularized by summing over triangulated surfaces. The inclusion of curvature in the action is a necessity for the scaling of the string tension. We discuss the physical properties of models with extrinsic curvature terms in the action and show that the string tension vanishes at the critical point where the bare extrinsic curvature coupling tends to infinity. Similar results are derived for models with intrinsic curvature. (orig.)

  14. The effect of increasing membrane curvature on the phase transition and mixing behavior of a dimyristoyl-sn-glycero-3-phosphatidylcholine/distearoyl-sn-glycero-3-phosphatidylcholine lipid mixture as studied by Fourier transform infrared spectroscopy and differential scanning calorimetry

    DEFF Research Database (Denmark)

    Brumm, T.; Jørgensen, Kent; Mouritsen, Ole G.

    1996-01-01

    The phase transition behavior of a lipid bilayer of dimyristoyl-sn-glycero-3-phosphalidylcholine/distearoyl-sn- glycero-3-phosphatidylcholine (DMPC-d54/DSPC) (1:1) on a solid support with varying curvatures was investigated with differential scanning calorimetry, infrared spectroscopy, and model...... of the liquidus point can be understood as a reduction of the lateral pressure in the bilayer with increasing curvature. The shift of the solidus line is interpreted as a result of the increased demixing of the two components in the two-phase region with increasing curvature due to lowering of the lateral...

  15. Brane cosmology with curvature corrections

    International Nuclear Information System (INIS)

    Kofinas, Georgios; Maartens, Roy; Papantonopoulos, Eleftherios

    2003-01-01

    We study the cosmology of the Randall-Sundrum brane-world where the Einstein-Hilbert action is modified by curvature correction terms: a four-dimensional scalar curvature from induced gravity on the brane, and a five-dimensional Gauss-Bonnet curvature term. The combined effect of these curvature corrections to the action removes the infinite-density big bang singularity, although the curvature can still diverge for some parameter values. A radiation brane undergoes accelerated expansion near the minimal scale factor, for a range of parameters. This acceleration is driven by the geometric effects, without an inflation field or negative pressures. At late times, conventional cosmology is recovered. (author)

  16. On Gauss-Bonnet Curvatures

    Directory of Open Access Journals (Sweden)

    Mohammed Larbi Labbi

    2007-12-01

    Full Text Available The $(2k$-th Gauss-Bonnet curvature is a generalization to higher dimensions of the $(2k$-dimensional Gauss-Bonnet integrand, it coincides with the usual scalar curvature for $k = 1$. The Gauss-Bonnet curvatures are used in theoretical physics to describe gravity in higher dimensional space times where they are known as the Lagrangian of Lovelock gravity, Gauss-Bonnet Gravity and Lanczos gravity. In this paper we present various aspects of these curvature invariants and review their variational properties. In particular, we discuss natural generalizations of the Yamabe problem, Einstein metrics and minimal submanifolds.

  17. Bacterial cell curvature through mechanical control of cell growth

    DEFF Research Database (Denmark)

    Cabeen, M.; Charbon, Godefroid; Vollmer, W.

    2009-01-01

    The cytoskeleton is a key regulator of cell morphogenesis. Crescentin, a bacterial intermediate filament-like protein, is required for the curved shape of Caulobacter crescentus and localizes to the inner cell curvature. Here, we show that crescentin forms a single filamentous structure...... that collapses into a helix when detached from the cell membrane, suggesting that it is normally maintained in a stretched configuration. Crescentin causes an elongation rate gradient around the circumference of the sidewall, creating a longitudinal cell length differential and hence curvature. Such curvature...... can be produced by physical force alone when cells are grown in circular microchambers. Production of crescentin in Escherichia coli is sufficient to generate cell curvature. Our data argue for a model in which physical strain borne by the crescentin structure anisotropically alters the kinetics...

  18. Manifolds of positive scalar curvature

    Energy Technology Data Exchange (ETDEWEB)

    Stolz, S [Department of Mathematics, University of Notre Dame, Notre Dame (United States)

    2002-08-15

    This lecture gives an survey on the problem of finding a positive scalar curvature metric on a closed manifold. The Gromov-Lawson-Rosenberg conjecture and its relation to the Baum-Connes conjecture are discussed and the problem of finding a positive Ricci curvature metric on a closed manifold is explained.

  19. Some Inequalities for the -Curvature Image

    Directory of Open Access Journals (Sweden)

    Daijun Wei

    2009-01-01

    Full Text Available Lutwak introduced the notion of -curvature image and proved an inequality for the volumes of convex body and its -curvature image. In this paper, we first give an monotonic property of -curvature image. Further, we establish two inequalities for the -curvature image and its polar, respectively. Finally, an inequality for the volumes of -projection body and -curvature image is obtained.

  20. Supported lipid bilayers with controlled curvature via colloidal lithography

    DEFF Research Database (Denmark)

    Sundh, Maria; Manandhar, Michal; Svedhem, Sofia

    2011-01-01

    Supported lipid bilayers (SLBs) at surfaces provide a route to quantitatively study molecular interactions with and at lipid membranes via different surface-based analytical techniques. Here, a method to fabricate SLBs with controlled curvatures, in the nanometer regime over large areas, is prese...

  1. Lectures on mean curvature flows

    CERN Document Server

    Zhu, Xi-Ping

    2002-01-01

    "Mean curvature flow" is a term that is used to describe the evolution of a hypersurface whose normal velocity is given by the mean curvature. In the simplest case of a convex closed curve on the plane, the properties of the mean curvature flow are described by Gage-Hamilton's theorem. This theorem states that under the mean curvature flow, the curve collapses to a point, and if the flow is diluted so that the enclosed area equals \\pi, the curve tends to the unit circle. In this book, the author gives a comprehensive account of fundamental results on singularities and the asymptotic behavior of mean curvature flows in higher dimensions. Among other topics, he considers in detail Huisken's theorem (a generalization of Gage-Hamilton's theorem to higher dimension), evolution of non-convex curves and hypersurfaces, and the classification of singularities of the mean curvature flow. Because of the importance of the mean curvature flow and its numerous applications in differential geometry and partial differential ...

  2. Environmental influences on DNA curvature

    DEFF Research Database (Denmark)

    Ussery, David; Higgins, C.F.; Bolshoy, A.

    1999-01-01

    DNA curvature plays an important role in many biological processes. To study environmentalinfluences on DNA curvature we compared the anomalous migration on polyacrylamide gels ofligation ladders of 11 specifically-designed oligonucleotides. At low temperatures (25 degreesC and below) most......, whilst spermine enhanced theanomalous migration of a different set of sequences. Sequences with a GGC motif exhibitedgreater curvature than predicted by the presently-used angles for the nearest-neighbour wedgemodel and are especially sensitive to Mg2+. The data have implications for models...... for DNAcurvature and for environmentally-sensitive DNA conformations in the regulation of geneexpression....

  3. Curvature force and dark energy

    International Nuclear Information System (INIS)

    Balakin, Alexander B; Pavon, Diego; Schwarz, Dominik J; Zimdahl, Winfried

    2003-01-01

    A curvature self-interaction of the cosmic gas is shown to mimic a cosmological constant or other forms of dark energy, such as a rolling tachyon condensate or a Chaplygin gas. Any given Hubble rate and deceleration parameter can be traced back to the action of an effective curvature force on the gas particles. This force self-consistently reacts back on the cosmological dynamics. The links between an imperfect fluid description, a kinetic description with effective antifriction forces and curvature forces, which represent a non-minimal coupling of gravity to matter, are established

  4. Discrete Curvature Theories and Applications

    KAUST Repository

    Sun, Xiang

    2016-08-25

    Discrete Di erential Geometry (DDG) concerns discrete counterparts of notions and methods in di erential geometry. This thesis deals with a core subject in DDG, discrete curvature theories on various types of polyhedral surfaces that are practically important for free-form architecture, sunlight-redirecting shading systems, and face recognition. Modeled as polyhedral surfaces, the shapes of free-form structures may have to satisfy di erent geometric or physical constraints. We study a combination of geometry and physics { the discrete surfaces that can stand on their own, as well as having proper shapes for the manufacture. These proper shapes, known as circular and conical meshes, are closely related to discrete principal curvatures. We study curvature theories that make such surfaces possible. Shading systems of freeform building skins are new types of energy-saving structures that can re-direct the sunlight. From these systems, discrete line congruences across polyhedral surfaces can be abstracted. We develop a new curvature theory for polyhedral surfaces equipped with normal congruences { a particular type of congruences de ned by linear interpolation of vertex normals. The main results are a discussion of various de nitions of normality, a detailed study of the geometry of such congruences, and a concept of curvatures and shape operators associated with the faces of a triangle mesh. These curvatures are compatible with both normal congruences and the Steiner formula. In addition to architecture, we consider the role of discrete curvatures in face recognition. We use geometric measure theory to introduce the notion of asymptotic cones associated with a singular subspace of a Riemannian manifold, which is an extension of the classical notion of asymptotic directions. We get a simple expression of these cones for polyhedral surfaces, as well as convergence and approximation theorems. We use the asymptotic cones as facial descriptors and demonstrate the

  5. Curvature bound from gravitational catalysis

    Science.gov (United States)

    Gies, Holger; Martini, Riccardo

    2018-04-01

    We determine bounds on the curvature of local patches of spacetime from the requirement of intact long-range chiral symmetry. The bounds arise from a scale-dependent analysis of gravitational catalysis and its influence on the effective potential for the chiral order parameter, as induced by fermionic fluctuations on a curved spacetime with local hyperbolic properties. The bound is expressed in terms of the local curvature scalar measured in units of a gauge-invariant coarse-graining scale. We argue that any effective field theory of quantum gravity obeying this curvature bound is safe from chiral symmetry breaking through gravitational catalysis and thus compatible with the simultaneous existence of chiral fermions in the low-energy spectrum. With increasing number of dimensions, the curvature bound in terms of the hyperbolic scale parameter becomes stronger. Applying the curvature bound to the asymptotic safety scenario for quantum gravity in four spacetime dimensions translates into bounds on the matter content of particle physics models.

  6. The role of curvature in silica mesoporous crystals

    KAUST Repository

    Miyasaka, Keiichi; Bennett, Alfonso Garcia; Han, Lu; Han, Yu; Xiao, Changhong; Fujita, Nobuhisa; Castle, Toen; Sakamoto, Yasuhiro; Che, Shunai; Terasaki, Osamu

    2012-01-01

    Silica mesoporous crystals (SMCs) offer a unique opportunity to study micellar mesophases. Replication of non-equilibrium mesophases into porous silica structures allows the characterization of surfactant phases under a variety of chemical and physical perturbations, through methods not typically accessible to liquid crystal chemists. A poignant example is the use of electron microscopy and crystallography, as discussed herein, for the purpose of determining the fundamental role of amphiphile curvature, namely mean curvature and Gaussian curvature, which have been extensively studied in various fields such as polymer, liquid crystal, biological membrane, etc. The present work aims to highlight some current studies devoted to the interface curvature on SMCs, in which electron microscopy and electron crystallography (EC) are used to understand the geometry of silica wall surface in bicontinuous and cage-type mesostructures through the investigation of electrostatic potential maps. Additionally, we show that by altering the synthesis conditions during the preparation of SMCs, it is possible to isolate particles during micellar mesophase transformations in the cubic bicontinuous system, allowing us to view and study epitaxial relations under the specific synthesis conditions. By studying the relationship between mesoporous structure, interface curvature and micellar mesophases using electron microscopy and EC, we hope to bring new insights into the formation mechanism of these unique materials but also contribute a new way of understanding periodic liquid crystal systems. © 2012 The Royal Society.

  7. The role of curvature in silica mesoporous crystals

    KAUST Repository

    Miyasaka, Keiichi

    2012-02-08

    Silica mesoporous crystals (SMCs) offer a unique opportunity to study micellar mesophases. Replication of non-equilibrium mesophases into porous silica structures allows the characterization of surfactant phases under a variety of chemical and physical perturbations, through methods not typically accessible to liquid crystal chemists. A poignant example is the use of electron microscopy and crystallography, as discussed herein, for the purpose of determining the fundamental role of amphiphile curvature, namely mean curvature and Gaussian curvature, which have been extensively studied in various fields such as polymer, liquid crystal, biological membrane, etc. The present work aims to highlight some current studies devoted to the interface curvature on SMCs, in which electron microscopy and electron crystallography (EC) are used to understand the geometry of silica wall surface in bicontinuous and cage-type mesostructures through the investigation of electrostatic potential maps. Additionally, we show that by altering the synthesis conditions during the preparation of SMCs, it is possible to isolate particles during micellar mesophase transformations in the cubic bicontinuous system, allowing us to view and study epitaxial relations under the specific synthesis conditions. By studying the relationship between mesoporous structure, interface curvature and micellar mesophases using electron microscopy and EC, we hope to bring new insights into the formation mechanism of these unique materials but also contribute a new way of understanding periodic liquid crystal systems. © 2012 The Royal Society.

  8. Studying biomolecule localization by engineering bacterial cell wall curvature.

    Directory of Open Access Journals (Sweden)

    Lars D Renner

    Full Text Available In this article we describe two techniques for exploring the relationship between bacterial cell shape and the intracellular organization of proteins. First, we created microchannels in a layer of agarose to reshape live bacterial cells and predictably control their mean cell wall curvature, and quantified the influence of curvature on the localization and distribution of proteins in vivo. Second, we used agarose microchambers to reshape bacteria whose cell wall had been chemically and enzymatically removed. By combining microstructures with different geometries and fluorescence microscopy, we determined the relationship between bacterial shape and the localization for two different membrane-associated proteins: i the cell-shape related protein MreB of Escherichia coli, which is positioned along the long axis of the rod-shaped cell; and ii the negative curvature-sensing cell division protein DivIVA of Bacillus subtilis, which is positioned primarily at cell division sites. Our studies of intracellular organization in live cells of E. coli and B. subtilis demonstrate that MreB is largely excluded from areas of high negative curvature, whereas DivIVA localizes preferentially to regions of high negative curvature. These studies highlight a unique approach for studying the relationship between cell shape and intracellular organization in intact, live bacteria.

  9. Surface meshing with curvature convergence

    KAUST Repository

    Li, Huibin; Zeng, Wei; Morvan, Jean-Marie; Chen, Liming; Gu, Xianfengdavid

    2014-01-01

    Surface meshing plays a fundamental role in graphics and visualization. Many geometric processing tasks involve solving geometric PDEs on meshes. The numerical stability, convergence rates and approximation errors are largely determined by the mesh qualities. In practice, Delaunay refinement algorithms offer satisfactory solutions to high quality mesh generations. The theoretical proofs for volume based and surface based Delaunay refinement algorithms have been established, but those for conformal parameterization based ones remain wide open. This work focuses on the curvature measure convergence for the conformal parameterization based Delaunay refinement algorithms. Given a metric surface, the proposed approach triangulates its conformal uniformization domain by the planar Delaunay refinement algorithms, and produces a high quality mesh. We give explicit estimates for the Hausdorff distance, the normal deviation, and the differences in curvature measures between the surface and the mesh. In contrast to the conventional results based on volumetric Delaunay refinement, our stronger estimates are independent of the mesh structure and directly guarantee the convergence of curvature measures. Meanwhile, our result on Gaussian curvature measure is intrinsic to the Riemannian metric and independent of the embedding. In practice, our meshing algorithm is much easier to implement and much more efficient. The experimental results verified our theoretical results and demonstrated the efficiency of the meshing algorithm. © 2014 IEEE.

  10. Surface meshing with curvature convergence

    KAUST Repository

    Li, Huibin

    2014-06-01

    Surface meshing plays a fundamental role in graphics and visualization. Many geometric processing tasks involve solving geometric PDEs on meshes. The numerical stability, convergence rates and approximation errors are largely determined by the mesh qualities. In practice, Delaunay refinement algorithms offer satisfactory solutions to high quality mesh generations. The theoretical proofs for volume based and surface based Delaunay refinement algorithms have been established, but those for conformal parameterization based ones remain wide open. This work focuses on the curvature measure convergence for the conformal parameterization based Delaunay refinement algorithms. Given a metric surface, the proposed approach triangulates its conformal uniformization domain by the planar Delaunay refinement algorithms, and produces a high quality mesh. We give explicit estimates for the Hausdorff distance, the normal deviation, and the differences in curvature measures between the surface and the mesh. In contrast to the conventional results based on volumetric Delaunay refinement, our stronger estimates are independent of the mesh structure and directly guarantee the convergence of curvature measures. Meanwhile, our result on Gaussian curvature measure is intrinsic to the Riemannian metric and independent of the embedding. In practice, our meshing algorithm is much easier to implement and much more efficient. The experimental results verified our theoretical results and demonstrated the efficiency of the meshing algorithm. © 2014 IEEE.

  11. A prescribing geodesic curvature problem

    International Nuclear Information System (INIS)

    Chang, K.C.; Liu, J.Q.

    1993-09-01

    Let D be the unit disk and k be a function on S 1 = δD. Find a flat metric which is pointwise conformal to the standard metric and has k as the geodesic curvature of S 1 . A sufficient condition for the existence of such a metric is that the harmonic extension of k in D has saddle points. (author). 11 refs

  12. Cosmic curvature tested directly from observations

    Science.gov (United States)

    Denissenya, Mikhail; Linder, Eric V.; Shafieloo, Arman

    2018-03-01

    Cosmic spatial curvature is a fundamental geometric quantity of the Universe. We investigate a model independent, geometric approach to measure spatial curvature directly from observations, without any derivatives of data. This employs strong lensing time delays and supernova distance measurements to measure the curvature itself, rather than just testing consistency with flatness. We define two curvature estimators, with differing error propagation characteristics, that can crosscheck each other, and also show how they can be used to map the curvature in redshift slices, to test constancy of curvature as required by the Robertson-Walker metric. Simulating realizations of redshift distributions and distance measurements of lenses and sources, we estimate uncertainties on the curvature enabled by next generation measurements. The results indicate that the model independent methods, using only geometry without assuming forms for the energy density constituents, can determine the curvature at the ~6×10‑3 level.

  13. Model-independent Constraints on Cosmic Curvature and Opacity

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Guo-Jian; Li, Zheng-Xiang; Xia, Jun-Qing; Zhu, Zong-Hong [Department of Astronomy, Beijing Normal University, Beijing 100875 (China); Wei, Jun-Jie, E-mail: gjwang@mail.bnu.edu.cn, E-mail: zxli918@bnu.edu.cn, E-mail: xiajq@bnu.edu.cn, E-mail: zhuzh@bnu.edu.cn, E-mail: jjwei@pmo.ac.cn [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2017-09-20

    In this paper, we propose to estimate the spatial curvature of the universe and the cosmic opacity in a model-independent way with expansion rate measurements, H ( z ), and type Ia supernova (SNe Ia). On the one hand, using a nonparametric smoothing method Gaussian process, we reconstruct a function H ( z ) from opacity-free expansion rate measurements. Then, we integrate the H ( z ) to obtain distance modulus μ {sub H}, which is dependent on the cosmic curvature. On the other hand, distances of SNe Ia can be determined by their photometric observations and thus are opacity-dependent. In our analysis, by confronting distance moduli μ {sub H} with those obtained from SNe Ia, we achieve estimations for both the spatial curvature and the cosmic opacity without any assumptions for the cosmological model. Here, it should be noted that light curve fitting parameters, accounting for the distance estimation of SNe Ia, are determined in a global fit together with the cosmic opacity and spatial curvature to get rid of the dependence of these parameters on cosmology. In addition, we also investigate whether the inclusion of different priors for the present expansion rate ( H {sub 0}: global estimation, 67.74 ± 0.46 km s{sup −1} Mpc{sup −1}, and local measurement, 73.24 ± 1.74 km s{sup −1} Mpc{sup −1}) exert influence on the reconstructed H ( z ) and the following estimations of the spatial curvature and cosmic opacity. Results show that, in general, a spatially flat and transparent universe is preferred by the observations. Moreover, it is suggested that priors for H {sub 0} matter a lot. Finally, we find that there is a strong degeneracy between the curvature and the opacity.

  14. Curvature Entropy for Curved Profile Generation

    OpenAIRE

    Ujiie, Yoshiki; Kato, Takeo; Sato, Koichiro; Matsuoka, Yoshiyuki

    2012-01-01

    In a curved surface design, the overall shape features that emerge from combinations of shape elements are important. However, controlling the features of the overall shape in curved profiles is difficult using conventional microscopic shape information such as dimension. Herein two types of macroscopic shape information, curvature entropy and quadrature curvature entropy, quantitatively represent the features of the overall shape. The curvature entropy is calculated by the curvature distribu...

  15. A remark about the mean curvature

    International Nuclear Information System (INIS)

    Zhang Weitao.

    1992-11-01

    In this paper, we give an integral identity about the mean curvature in Sobolev space H 0 1 (Ω) intersection H 2 (Ω). Suppose the mean curvature on Γ=δΩ is positive, we prove some inequalities of the positive mean curvature and propose some open problems. (author). 4 refs

  16. The dark side of curvature

    International Nuclear Information System (INIS)

    Barenboim, Gabriela; Martínez, Enrique Fernández; Mena, Olga; Verde, Licia

    2010-01-01

    Geometrical tests such as the combination of the Hubble parameter H(z) and the angular diameter distance d A (z) can, in principle, break the degeneracy between the dark energy equation of state parameter w(z), and the spatial curvature Ω k in a direct, model-independent way. In practice, constraints on these quantities achievable from realistic experiments, such as those to be provided by Baryon Acoustic Oscillation (BAO) galaxy surveys in combination with CMB data, can resolve the cosmic confusion between the dark energy equation of state parameter and curvature only statistically and within a parameterized model for w(z). Combining measurements of both H(z) and d A (z) up to sufficiently high redshifts z ∼ 2 and employing a parameterization of the redshift evolution of the dark energy equation of state are the keys to resolve the w(z)−Ω k degeneracy

  17. Modern approaches to discrete curvature

    CERN Document Server

    Romon, Pascal

    2017-01-01

     This book provides a valuable glimpse into discrete curvature, a rich new field of research which blends discrete mathematics, differential geometry, probability and computer graphics. It includes a vast collection of ideas and tools which will offer something new to all interested readers. Discrete geometry has arisen as much as a theoretical development as in response to unforeseen challenges coming from applications. Discrete and continuous geometries have turned out to be intimately connected. Discrete curvature is the key concept connecting them through many bridges in numerous fields: metric spaces, Riemannian and Euclidean geometries, geometric measure theory, topology, partial differential equations, calculus of variations, gradient flows, asymptotic analysis, probability, harmonic analysis, graph theory, etc. In spite of its crucial importance both in theoretical mathematics and in applications, up to now, almost no books have provided a coherent outlook on this emerging field.

  18. Curvature Entropy for Curved Profile Generation

    Directory of Open Access Journals (Sweden)

    Koichiro Sato

    2012-03-01

    Full Text Available In a curved surface design, the overall shape features that emerge from combinations of shape elements are important. However, controlling the features of the overall shape in curved profiles is difficult using conventional microscopic shape information such as dimension. Herein two types of macroscopic shape information, curvature entropy and quadrature curvature entropy, quantitatively represent the features of the overall shape. The curvature entropy is calculated by the curvature distribution, and represents the complexity of a shape (one of the overall shape features. The quadrature curvature entropy is an improvement of the curvature entropy by introducing a Markov process to evaluate the continuity of a curvature and to approximate human cognition of the shape. Additionally, a shape generation method using a genetic algorithm as a calculator and the entropy as a shape generation index is presented. Finally, the applicability of the proposed method is demonstrated using the side view of an automobile as a design example.

  19. Dynamic Double Curvature Mould System

    DEFF Research Database (Denmark)

    Jepsen, Christian Raun; Kristensen, Mathias Kræmmergaard; Kirkegaard, Poul Henning

    2011-01-01

    The present paper describes a concept for a reconfigurable mould surface which is designed to fit the needs of contemporary architecture. The core of the concept presented is a dynamic surface manipulated into a given shape using a digital signal created directly from the CAD drawing of the design....... This happens fast, automatic and without production of waste, and the manipulated surface is fair and robust, eliminating the need for additional, manual treatment. Limitations to the possibilities of the flexible form are limited curvature and limited level of detail, making it especially suited for larger...

  20. Trans-membrane area asymmetry controls the shape of cellular organelles

    NARCIS (Netherlands)

    Beznoussenko, Galina V; Pilyugin, Sergei S; Geerts, Willie J C; Kozlov, Michael M; Burger, Koert N J; Luini, Alberto; Derganc, Jure; Mironov, Alexander A

    2015-01-01

    Membrane organelles often have complicated shapes and differ in their volume, surface area and membrane curvature. The ratio between the surface area of the cytosolic and luminal leaflets (trans-membrane area asymmetry (TAA)) determines the membrane curvature within different sites of the organelle.

  1. Curvature-Controlled Topological Defects

    Directory of Open Access Journals (Sweden)

    Luka Mesarec

    2017-05-01

    Full Text Available Effectively, two-dimensional (2D closed films exhibiting in-plane orientational ordering (ordered shells might be instrumental for the realization of scaled crystals. In them, ordered shells are expected to play the role of atoms. Furthermore, topological defects (TDs within them would determine their valence. Namely, bonding among shells within an isotropic liquid matrix could be established via appropriate nano-binders (i.e., linkers which tend to be attached to the cores of TDs exploiting the defect core replacement mechanism. Consequently, by varying configurations of TDs one could nucleate growth of scaled crystals displaying different symmetries. For this purpose, it is of interest to develop a simple and robust mechanism via which one could control the position and number of TDs in such atoms. In this paper, we use a minimal mesoscopic model, where variational parameters are the 2D curvature tensor and the 2D orientational tensor order parameter. We demonstrate numerically the efficiency of the effective topological defect cancellation mechanism to predict positional assembling of TDs in ordered films characterized by spatially nonhomogeneous Gaussian curvature. Furthermore, we show how one could efficiently switch among qualitatively different structures by using a relative volume v of ordered shells, which represents a relatively simple naturally accessible control parameter.

  2. Evolution of a Rippled Membrane during Phospholipase A2 Hydrolysis Studied by Time-Resolved AFM

    DEFF Research Database (Denmark)

    Leidy, Chad; Mouritsen, Ole G.; Jørgensen, Kent

    2004-01-01

    The sensitivity of phospholipase A2 (PLA2) for lipid membrane curvature is explored by monitoring, through time-resolved atomic force microscopy, the hydrolysis of supported double bilayers in the ripple phase. The ripple phase presents a corrugated morphology. PLA2 is shown to have higher activity...... toward the ripple phase compared to the gel phase in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) membranes, indicating its preference for this highly curved membrane morphology. Hydrolysis of the stable and metastable ripple structures is monitored for equimolar DMPC/1,2-distearoyl- sn-glycero-3....... This is reflected in an increase in ripple spacing, followed by a sudden flattening of the lipid membrane during hydrolysis. Hydrolysis of the ripple phase results in anisotropic holes running parallel to the ripples, suggesting that the ripple phase has strip regions of higher sensitivity to enzymatic attack. Bulk...

  3. Higher curvature supergravity and cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Ferrara, Sergio [Th-Ph Department, CERN, Geneva (Switzerland); U.C.L.A., Los Angeles, CA (United States); INFN - LNF, Frascati (Italy); Sagnotti, Augusto [Scuola Normale Superiore, Pisa (Italy); INFN, Pisa (Italy)

    2016-04-15

    In this contribution we describe dual higher-derivative formulations of some cosmological models based on supergravity. Work in this direction started with the R + R{sup 2} Starobinsky model, whose supersymmetric extension was derived in the late 80's and was recently revived in view of new CMB data. Models dual to higher-derivative theories are subject to more restrictions than their bosonic counterparts or standard supergravity. The three sections are devoted to a brief description of R + R{sup 2} supergravity, to a scale invariant R{sup 2} supergravity and to theories with a nilpotent curvature, whose duals describe non-linear realizations (in the form of a Volkov-Akulov constrained superfield) coupled to supergravity. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. SLED phenomenology: curvature vs. volume

    International Nuclear Information System (INIS)

    Niedermann, Florian; Schneider, Robert

    2016-01-01

    We assess the question whether the SLED (Supersymmetric Large Extra Dimensions) model admits phenomenologically viable solutions with 4D maximal symmetry. We take into account a finite brane width and a scale invariance (SI) breaking dilaton-brane coupling, both of which should be included in a realistic setup. Provided that the brane tension and the microscopic size of the brane take generic values set by the fundamental bulk Planck scale, we find that either the 4D curvature or the size of the extra dimensions is unacceptably large. Since this result is independent of the dilaton-brane couplings, it provides the biggest challenge to the SLED program. In addition, to quantify its potential with respect to the cosmological constant problem, we infer the amount of tuning on model parameters required to obtain a sufficiently small 4D curvature. A first answer was recently given in http://dx.doi.org/10.1007/JHEP02(2016)025, showing that 4D flat solutions are only ensured in the SI case by imposing a tuning relation, even if a brane-localized flux is included. In this companion paper, we find that the tuning can in fact be avoided for certain SI breaking brane-dilaton couplings, but only at the price of worsening the phenomenological problem. Our results are obtained by solving the full coupled Einstein-dilaton system in a completely consistent way. The brane width is implemented using a well-known ring regularization. In passing, we note that for the couplings considered here the results of http://dx.doi.org/10.1007/JHEP02(2016)025 (which only treated infinitely thin branes) are all consistently recovered in the thin brane limit, and how this can be reconciled with the concerns about their correctness, recently brought up in http://dx.doi.org/10.1007/JHEP01(2016)017.

  5. Curvature recognition and force generation in phagocytosis

    Directory of Open Access Journals (Sweden)

    Prassler Jana

    2010-12-01

    Full Text Available Abstract Background The uptake of particles by actin-powered invagination of the plasma membrane is common to protozoa and to phagocytes involved in the immune response of higher organisms. The question addressed here is how a phagocyte may use geometric cues to optimize force generation for the uptake of a particle. We survey mechanisms that enable a phagocyte to remodel actin organization in response to particles of complex shape. Results Using particles that consist of two lobes separated by a neck, we found that Dictyostelium cells transmit signals concerning the curvature of a surface to the actin system underlying the plasma membrane. Force applied to a concave region can divide a particle in two, allowing engulfment of the portion first encountered. The phagosome membrane that is bent around the concave region is marked by a protein containing an inverse Bin-Amphiphysin-Rvs (I-BAR domain in combination with an Src homology (SH3 domain, similar to mammalian insulin receptor tyrosine kinase substrate p53. Regulatory proteins enable the phagocyte to switch activities within seconds in response to particle shape. Ras, an inducer of actin polymerization, is activated along the cup surface. Coronin, which limits the lifetime of actin structures, is reversibly recruited to the cup, reflecting a program of actin depolymerization. The various forms of myosin-I are candidate motor proteins for force generation in particle uptake, whereas myosin-II is engaged only in retracting a phagocytic cup after a switch to particle release. Thus, the constriction of a phagocytic cup differs from the contraction of a cleavage furrow in mitosis. Conclusions Phagocytes scan a particle surface for convex and concave regions. By modulating the spatiotemporal pattern of actin organization, they are capable of switching between different modes of interaction with a particle, either arresting at a concave region and applying force in an attempt to sever the particle

  6. Weyl tensors for asymmetric complex curvatures

    International Nuclear Information System (INIS)

    Oliveira, C.G.

    Considering a second rank Hermitian field tensor and a general Hermitian connection the associated complex curvature tensor is constructed. The Weyl tensor that corresponds to this complex curvature is determined. The formalism is applied to the Weyl unitary field theory and to the Moffat gravitational theory. (Author) [pt

  7. The curvature function in general relativity

    International Nuclear Information System (INIS)

    Hall, G S; MacNay, Lucy

    2006-01-01

    A function, here called the curvature function, is defined and which is constructed explicitly from the type (0, 4) curvature tensor. Although such a function may be defined for any manifold admitting a metric, attention is here concentrated on this function on a spacetime. Some properties of this function are explored and compared with a previous discussion of it given by Petrov

  8. Integrating 3D seismic curvature and curvature gradient attributes for fracture characterization: Methodologies and interpretational implications

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Dengliang

    2013-03-01

    In 3D seismic interpretation, curvature is a popular attribute that depicts the geometry of seismic reflectors and has been widely used to detect faults in the subsurface; however, it provides only part of the solutions to subsurface structure analysis. This study extends the curvature algorithm to a new curvature gradient algorithm, and integrates both algorithms for fracture detection using a 3D seismic test data set over Teapot Dome (Wyoming). In fractured reservoirs at Teapot Dome known to be formed by tectonic folding and faulting, curvature helps define the crestal portion of the reservoirs that is associated with strong seismic amplitude and high oil productivity. In contrast, curvature gradient helps better define the regional northwest-trending and the cross-regional northeast-trending lineaments that are associated with weak seismic amplitude and low oil productivity. In concert with previous reports from image logs, cores, and outcrops, the current study based on an integrated seismic curvature and curvature gradient analysis suggests that curvature might help define areas of enhanced potential to form tensile fractures, whereas curvature gradient might help define zones of enhanced potential to develop shear fractures. In certain fractured reservoirs such as at Teapot Dome where faulting and fault-related folding contribute dominantly to the formation and evolution of fractures, curvature and curvature gradient attributes can be potentially applied to differentiate fracture mode, to predict fracture intensity and orientation, to detect fracture volume and connectivity, and to model fracture networks.

  9. Curvature function and coarse graining

    International Nuclear Information System (INIS)

    Diaz-Marin, Homero; Zapata, Jose A.

    2010-01-01

    A classic theorem in the theory of connections on principal fiber bundles states that the evaluation of all holonomy functions gives enough information to characterize the bundle structure (among those sharing the same structure group and base manifold) and the connection up to a bundle equivalence map. This result and other important properties of holonomy functions have encouraged their use as the primary ingredient for the construction of families of quantum gauge theories. However, in these applications often the set of holonomy functions used is a discrete proper subset of the set of holonomy functions needed for the characterization theorem to hold. We show that the evaluation of a discrete set of holonomy functions does not characterize the bundle and does not constrain the connection modulo gauge appropriately. We exhibit a discrete set of functions of the connection and prove that in the abelian case their evaluation characterizes the bundle structure (up to equivalence), and constrains the connection modulo gauge up to ''local details'' ignored when working at a given scale. The main ingredient is the Lie algebra valued curvature function F S (A) defined below. It covers the holonomy function in the sense that expF S (A)=Hol(l=∂S,A).

  10. Curvature and torsion in growing actin networks

    International Nuclear Information System (INIS)

    Shaevitz, Joshua W; Fletcher, Daniel A

    2008-01-01

    Intracellular pathogens such as Listeria monocytogenes and Rickettsia rickettsii move within a host cell by polymerizing a comet-tail of actin fibers that ultimately pushes the cell forward. This dense network of cross-linked actin polymers typically exhibits a striking curvature that causes bacteria to move in gently looping paths. Theoretically, tail curvature has been linked to details of motility by considering force and torque balances from a finite number of polymerizing filaments. Here we track beads coated with a prokaryotic activator of actin polymerization in three dimensions to directly quantify the curvature and torsion of bead motility paths. We find that bead paths are more likely to have low rather than high curvature at any given time. Furthermore, path curvature changes very slowly in time, with an autocorrelation decay time of 200 s. Paths with a small radius of curvature, therefore, remain so for an extended period resulting in loops when confined to two dimensions. When allowed to explore a three-dimensional (3D) space, path loops are less evident. Finally, we quantify the torsion in the bead paths and show that beads do not exhibit a significant left- or right-handed bias to their motion in 3D. These results suggest that paths of actin-propelled objects may be attributed to slow changes in curvature, possibly associated with filament debranching, rather than a fixed torque

  11. Clustering on Membranes

    DEFF Research Database (Denmark)

    Johannes, Ludger; Pezeshkian, Weria; Ipsen, John H

    2018-01-01

    Clustering of extracellular ligands and proteins on the plasma membrane is required to perform specific cellular functions, such as signaling and endocytosis. Attractive forces that originate in perturbations of the membrane's physical properties contribute to this clustering, in addition to direct...... protein-protein interactions. However, these membrane-mediated forces have not all been equally considered, despite their importance. In this review, we describe how line tension, lipid depletion, and membrane curvature contribute to membrane-mediated clustering. Additional attractive forces that arise...... from protein-induced perturbation of a membrane's fluctuations are also described. This review aims to provide a survey of the current understanding of membrane-mediated clustering and how this supports precise biological functions....

  12. Conversion of radius of curvature to power (and vice versa)

    Science.gov (United States)

    Wickenhagen, Sven; Endo, Kazumasa; Fuchs, Ulrike; Youngworth, Richard N.; Kiontke, Sven R.

    2015-09-01

    Manufacturing optical components relies on good measurements and specifications. One of the most precise measurements routinely required is the form accuracy. In practice, form deviation from the ideal surface is effectively low frequency errors, where the form error most often accounts for no more than a few undulations across a surface. These types of errors are measured in a variety of ways including interferometry and tactile methods like profilometry, with the latter often being employed for aspheres and general surface shapes such as freeforms. This paper provides a basis for a correct description of power and radius of curvature tolerances, including best practices and calculating the power value with respect to the radius deviation (and vice versa) of the surface form. A consistent definition of the sagitta is presented, along with different cases in manufacturing that are of interest to fabricators and designers. The results make clear how the definitions and results should be documented, for all measurement setups. Relationships between power and radius of curvature are shown that allow specifying the preferred metric based on final accuracy and measurement method. Results shown include all necessary equations for conversion to give optical designers and manufacturers a consistent and robust basis for decision-making. The paper also gives guidance on preferred methods for different scenarios for surface types, accuracy required, and metrology methods employed.

  13. Right thoracic curvature in the normal spine

    Directory of Open Access Journals (Sweden)

    Masuda Keigo

    2011-01-01

    Full Text Available Abstract Background Trunk asymmetry and vertebral rotation, at times observed in the normal spine, resemble the characteristics of adolescent idiopathic scoliosis (AIS. Right thoracic curvature has also been reported in the normal spine. If it is determined that the features of right thoracic side curvature in the normal spine are the same as those observed in AIS, these findings might provide a basis for elucidating the etiology of this condition. For this reason, we investigated right thoracic curvature in the normal spine. Methods For normal spinal measurements, 1,200 patients who underwent a posteroanterior chest radiographs were evaluated. These consisted of 400 children (ages 4-9, 400 adolescents (ages 10-19 and 400 adults (ages 20-29, with each group comprised of both genders. The exclusion criteria were obvious chest and spinal diseases. As side curvature is minimal in normal spines and the range at which curvature is measured is difficult to ascertain, first the typical curvature range in scoliosis patients was determined and then the Cobb angle in normal spines was measured using the same range as the scoliosis curve, from T5 to T12. Right thoracic curvature was given a positive value. The curve pattern was organized in each collective three groups: neutral (from -1 degree to 1 degree, right (> +1 degree, and left ( Results In child group, Cobb angle in left was 120, in neutral was 125 and in right was 155. In adolescent group, Cobb angle in left was 70, in neutral was 114 and in right was 216. In adult group, Cobb angle in left was 46, in neutral was 102 and in right was 252. The curvature pattern shifts to the right side in the adolescent group (p Conclusions Based on standing chest radiographic measurements, a right thoracic curvature was observed in normal spines after adolescence.

  14. Pointlike Inclusion Interactions in Tubular Membranes

    NARCIS (Netherlands)

    Vahid Belarghou, A.; Idema, T.

    2016-01-01

    Membrane tubes and tubular networks are ubiquitous in living cells. Inclusions like proteins are vital for both the stability and the dynamics of such networks. These inclusions interact via the curvature deformations they impose on the membrane. We analytically study the resulting membrane

  15. Vertical melting of a stack of membranes

    Science.gov (United States)

    Borelli, M. E. S.; Kleinert, H.; Schakel, A. M. J.

    2001-02-01

    A stack of tensionless membranes with nonlinear curvature energy and vertical harmonic interaction is studied. At low temperatures, the system forms a lamellar phase. At a critical temperature, the stack disorders vertically in a melting-like transition.

  16. Discrete Curvatures and Discrete Minimal Surfaces

    KAUST Repository

    Sun, Xiang

    2012-01-01

    This thesis presents an overview of some approaches to compute Gaussian and mean curvature on discrete surfaces and discusses discrete minimal surfaces. The variety of applications of differential geometry in visualization and shape design leads

  17. Higher Curvature Supergravity, Supersymmetry Breaking and Inflation

    CERN Document Server

    Ferrara, Sergio

    2017-01-01

    In these lectures, after a short introduction to cosmology, we discuss the supergravity embedding of higher curvature models of inflation. The supergravity description of such models is presented for the two different formulations of minimal supergravity.

  18. Curvature of Indoor Sensor Network: Clustering Coefficient

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available We investigate the geometric properties of the communication graph in realistic low-power wireless networks. In particular, we explore the concept of the curvature of a wireless network via the clustering coefficient. Clustering coefficient analysis is a computationally simplified, semilocal approach, which nevertheless captures such a large-scale feature as congestion in the underlying network. The clustering coefficient concept is applied to three cases of indoor sensor networks, under varying thresholds on the link packet reception rate (PRR. A transition from positive curvature (“meshed” network to negative curvature (“core concentric” network is observed by increasing the threshold. Even though this paper deals with network curvature per se, we nevertheless expand on the underlying congestion motivation, propose several new concepts (network inertia and centroid, and finally we argue that greedy routing on a virtual positively curved network achieves load balancing on the physical network.

  19. The spinning particle with extrinsic curvature

    International Nuclear Information System (INIS)

    Dhar, A.

    1988-01-01

    We construct and analyse an action for the spinning particle which contains an extrinsic curvature term. A possible generalization of this construction to the case of the spinning string is also discussed. (orig.)

  20. GDP growth and the yield curvature

    DEFF Research Database (Denmark)

    Møller, Stig Vinther

    2014-01-01

    This paper examines the forecastability of GDP growth using information from the term structure of yields. In contrast to previous studies, the paper shows that the curvature of the yield curve contributes with much more forecasting power than the slope of yield curve. The yield curvature also...... predicts bond returns, implying a common element to time-variation in expected bond returns and expected GDP growth....

  1. Straight-line string with curvature

    International Nuclear Information System (INIS)

    Solov'ev, L.D.

    1995-01-01

    Classical and quantum solutions for the relativistic straight-line string with arbitrary dependence on the world surface curvature are obtained. They differ from the case of the usual Nambu-Goto interaction by the behaviour of the Regge trajectory which in general can be non-linear. A regularization of the action is considered and a comparison with relativistic point with curvature is made. 5 refs

  2. The effect of spontaneous curvature on a two-phase vesicle

    International Nuclear Information System (INIS)

    Cox, Geoffrey; Lowengrub, John

    2015-01-01

    Vesicles are membrane-bound structures commonly known for their roles in cellular transport and the shape of a vesicle is determined by its surrounding membrane (lipid bilayer). When the membrane is composed of different lipids, it is natural for the lipids of similar molecular structure to migrate towards one another (via spinodal decomposition), creating a multi-phase vesicle. In this article, we consider a two-phase vesicle model which is driven by nature's propensity to maintain a minimal state of elastic energy. The model assumes a continuum limit, thereby treating the membrane as a closed three-dimensional surface. The main purpose of this study is to reveal the complexity of the Helfrich two-phase vesicle model with non-zero spontaneous curvature and provide further evidence to support the relevance of spontaneous curvature as a modelling parameter. In this paper, we illustrate the complexity of the Helfrich two-phase model by providing multiple examples of undocumented solutions and energy hysteresis. We also investigate the influence of spontaneous curvature on morphological effects and membrane phenomena such as budding and fusion. (paper)

  3. Convective mass transfer in helical pipes: effect of curvature and torsion

    Energy Technology Data Exchange (ETDEWEB)

    Litster, S.; Djilali, N. [University of Victoria, Department of Mechanical Engineering, Victoria, BC (Canada); Pharoah, J.G. [University of Victoria, Department of Mechanical Engineering, Victoria, BC (Canada); Queen' s University at Kingston, Department of Mechanical Engineering, Kingston, ON (Canada)

    2006-03-01

    A 3D numerical analysis of the flow and mass transfer in helical pipes is presented. The interpretation of the flow patterns and their impact on mass transfer is shown to require a non-orthogonal pseudo-stream function based visualization. The strong coupling between torsion and curvature effects, and the resulting secondary flow regimes are well characterized by a parameter combining both the Dean (Dn) and Germano numbers (Gn). For membrane separation applications, helical modules combining high curvature with low torsion would alleviate concentration polarization and yield appreciable flux improvement. (orig.)

  4. Effective tension and fluctuations in active membranes.

    Science.gov (United States)

    Loubet, Bastien; Seifert, Udo; Lomholt, Michael Andersen

    2012-03-01

    We calculate the fluctuation spectrum of the shape of a lipid vesicle or cell exposed to a nonthermal source of noise. In particular, we take constraints on the membrane area and the volume of fluid that it encapsulates into account when obtaining expressions for the dependency of the membrane tension on the noise. We then investigate three possible origins of the nonthermal noise taken from the literature: A direct force, which models an external medium pushing on the membrane, a curvature force, which models a fluctuating spontaneous curvature, and a permeation force coming from an active transport of fluid through the membrane. For the direct force and curvature force cases, we compare our results to existing experiments on active membranes.

  5. Some Inequalities for the Lp-Curvature Image

    Directory of Open Access Journals (Sweden)

    Xiang Yu

    2009-01-01

    Full Text Available Lutwak introduced the notion of Lp-curvature image and proved an inequality for the volumes of convex body and its Lp-curvature image. In this paper, we first give an monotonic property of Lp-curvature image. Further, we establish two inequalities for the Lp-curvature image and its polar, respectively. Finally, an inequality for the volumes of Lp-projection body and Lp-curvature image is obtained.

  6. Extrinsic and intrinsic curvatures in thermodynamic geometry

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini Mansoori, Seyed Ali, E-mail: shossein@bu.edu [Department of Physics, Boston University, 590 Commonwealth Ave., Boston, MA 02215 (United States); Department of Physics, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Mirza, Behrouz, E-mail: b.mirza@cc.iut.ac.ir [Department of Physics, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Sharifian, Elham, E-mail: e.sharifian@ph.iut.ac.ir [Department of Physics, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of)

    2016-08-10

    We investigate the intrinsic and extrinsic curvatures of a certain hypersurface in thermodynamic geometry of a physical system and show that they contain useful thermodynamic information. For an anti-Reissner–Nordström-(A)de Sitter black hole (Phantom), the extrinsic curvature of a constant Q hypersurface has the same sign as the heat capacity around the phase transition points. The intrinsic curvature of the hypersurface can also be divergent at the critical points but has no information about the sign of the heat capacity. Our study explains the consistent relationship holding between the thermodynamic geometry of the KN-AdS black holes and those of the RN (J-zero hypersurface) and Kerr black holes (Q-zero hypersurface) ones [1]. This approach can easily be generalized to an arbitrary thermodynamic system.

  7. Extrinsic and intrinsic curvatures in thermodynamic geometry

    International Nuclear Information System (INIS)

    Hosseini Mansoori, Seyed Ali; Mirza, Behrouz; Sharifian, Elham

    2016-01-01

    We investigate the intrinsic and extrinsic curvatures of a certain hypersurface in thermodynamic geometry of a physical system and show that they contain useful thermodynamic information. For an anti-Reissner–Nordström-(A)de Sitter black hole (Phantom), the extrinsic curvature of a constant Q hypersurface has the same sign as the heat capacity around the phase transition points. The intrinsic curvature of the hypersurface can also be divergent at the critical points but has no information about the sign of the heat capacity. Our study explains the consistent relationship holding between the thermodynamic geometry of the KN-AdS black holes and those of the RN (J-zero hypersurface) and Kerr black holes (Q-zero hypersurface) ones [1]. This approach can easily be generalized to an arbitrary thermodynamic system.

  8. Substrate curvature gradient drives rapid droplet motion.

    Science.gov (United States)

    Lv, Cunjing; Chen, Chao; Chuang, Yin-Chuan; Tseng, Fan-Gang; Yin, Yajun; Grey, Francois; Zheng, Quanshui

    2014-07-11

    Making small liquid droplets move spontaneously on solid surfaces is a key challenge in lab-on-chip and heat exchanger technologies. Here, we report that a substrate curvature gradient can accelerate micro- and nanodroplets to high speeds on both hydrophilic and hydrophobic substrates. Experiments for microscale water droplets on tapered surfaces show a maximum speed of 0.42  m/s, 2 orders of magnitude higher than with a wettability gradient. We show that the total free energy and driving force exerted on a droplet are determined by the substrate curvature and substrate curvature gradient, respectively. Using molecular dynamics simulations, we predict nanoscale droplets moving spontaneously at over 100  m/s on tapered surfaces.

  9. Cosmic curvature from de Sitter equilibrium cosmology.

    Science.gov (United States)

    Albrecht, Andreas

    2011-10-07

    I show that the de Sitter equilibrium cosmology generically predicts observable levels of curvature in the Universe today. The predicted value of the curvature, Ω(k), depends only on the ratio of the density of nonrelativistic matter to cosmological constant density ρ(m)(0)/ρ(Λ) and the value of the curvature from the initial bubble that starts the inflation, Ω(k)(B). The result is independent of the scale of inflation, the shape of the potential during inflation, and many other details of the cosmology. Future cosmological measurements of ρ(m)(0)/ρ(Λ) and Ω(k) will open up a window on the very beginning of our Universe and offer an opportunity to support or falsify the de Sitter equilibrium cosmology.

  10. Radion stabilization in higher curvature warped spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Das, Ashmita [Indian Institute of Technology, Department of Physics, Guwahati, Assam (India); Mukherjee, Hiya; Paul, Tanmoy; SenGupta, Soumitra [Indian Association for the Cultivation of Science, Department of Theoretical Physics, Kolkata (India)

    2018-02-15

    We consider a five dimensional AdS spacetime in presence of higher curvature term like F(R) = R + αR{sup 2} in the bulk. In this model, we examine the possibility of modulus stabilization from the scalar degrees of freedom of higher curvature gravity free of ghosts. Our result reveals that the model stabilizes itself and the mechanism of modulus stabilization can be argued from a geometric point of view. We determine the region of the parametric space for which the modulus (or radion) can to be stabilized. We also show how the mass and coupling parameters of radion field are modified due to higher curvature term leading to modifications of its phenomenological implications on the visible 3-brane. (orig.)

  11. Electrodiffusion of Lipids on Membrane Surfaces

    OpenAIRE

    Zhou, Y. C.

    2011-01-01

    Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic interactions and membrane curvature. Though the lateral diffusion rates of lipids on membrane of various compositions are measured and the electrostatic free energies of predetermined protein-membrane-lipid systems can be computed, the process of the aggregati...

  12. Longitudinal surface curvature effect in magnetohydrodynamics

    International Nuclear Information System (INIS)

    Bodas, N.G.

    1975-01-01

    The two-dimensional motion of an incompressible and electrically conducting fluid past an electrically insulated body surface (having curvature) is studied for a given O(1) basic flow and magnetic field, when (i) the applied magnetic field is aligned with the velocity in the basic flow, and (ii) the applied magnetic field is within the body surface. 01 and 0(Re sup(1/2)) mean the first and second order approximations respectively in an exansion scheme in powers of Resup(-1/2), Re being the Reynolds number). The technique of matched asymptotic expansions is used to solve the problem. The governing partial differential equations to 0(Resup(-1/2)) boundary layer approximation are found to give similarity solutions for a family of surface curvature and pressure gradient distributions in case (i), and for uniform basic flow with analytic surface curvature distributions in case (ii). The equations are solved numerically. In case (i) it is seen that the effect of the magnetic field on the skin-friction- correction due to the curvature is very small. Also the magnetic field at the wall is reduced by the curvature on the convex side. In case (ii) the magnetic field significantly increases the skin-friction-correction due to the curvature. The effect of the magnetic field on the O(1) and O(Resup(-1/2)) skin friction coefficients increases with the increase of the electrical conductivity of the fluid. Also, at higher values of the magnetic pressure, moderate changes in the electrical conductivity do not influence the correction to the skin-friction significantly. (Auth.)

  13. Connections and curvatures on complex Riemannian manifolds

    International Nuclear Information System (INIS)

    Ganchev, G.; Ivanov, S.

    1991-05-01

    Characteristic connection and characteristic holomorphic sectional curvatures are introduced on a complex Riemannian manifold (not necessarily with holomorphic metric). For the class of complex Riemannian manifolds with holomorphic characteristic connection a classification of the manifolds with (pointwise) constant holomorphic characteristic curvature is given. It is shown that the conformal geometry of complex analytic Riemannian manifolds can be naturally developed on the class of locally conformal holomorphic Riemannian manifolds. Complex Riemannian manifolds locally conformal to the complex Euclidean space are characterized with zero conformal fundamental tensor and zero conformal characteristic tensor. (author). 12 refs

  14. Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment.

    Directory of Open Access Journals (Sweden)

    Ruben R Bender

    2016-06-01

    Full Text Available Receptor-targeted lentiviral vectors (LVs can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties that cell surface proteins must fulfill to act as receptors for viral glycoproteins. Here we show that LVs pseudotyped with receptor-targeted Nipah virus (NiV glycoproteins effectively enter into cells when they use cell surface proteins as receptors that bring them closely enough to the cell membrane (less than 100 Å distance. Then, they were flexible in receptor usage as demonstrated by successful targeting of EpCAM, CD20, and CD8, and as selective as LVs pseudotyped with receptor-targeted measles virus (MV glycoproteins, the current standard for cell-type specific gene delivery. Remarkably, NiV-LVs could be produced at up to two orders of magnitude higher titers compared to their MV-based counterparts and were at least 10,000-fold less effectively neutralized than MV glycoprotein pseudotyped LVs by pooled human intravenous immunoglobulin. An important finding for NiV-LVs targeted to Her2/neu was an about 100-fold higher gene transfer activity when particles were targeted to membrane-proximal regions as compared to particles binding to a more membrane-distal epitope. Likewise, the low gene transfer activity mediated by NiV-LV particles bound to the membrane distal domains of CD117 or the glutamate receptor subunit 4 (GluA4 was substantially enhanced by reducing receptor size to below 100 Å. Overall, the data suggest that the NiV glycoproteins are optimally suited for cell-type specific gene delivery with LVs and, in addition, for the first time define which parts of a cell surface protein should be targeted to achieve optimal gene transfer rates with receptor-targeted LVs.

  15. Independent preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    1991-01-01

    A simple mathematical result characterizing a subset of a product set is proved and used to obtain additive representations of preferences. The additivity consequences of independence assumptions are obtained for preferences which are not total or transitive. This means that most of the economic ...... theory based on additive preferences - expected utility, discounted utility - has been generalized to preferences which are not total or transitive. Other economic applications of the theorem are given...

  16. Zero curvature conditions and conformal covariance

    International Nuclear Information System (INIS)

    Akemann, G.; Grimm, R.

    1992-05-01

    Two-dimensional zero curvature conditions were investigated in detail, with special emphasis on conformal properties, and the appearance of covariant higher order differential operators constructed in terms of a projective connection was elucidated. The analysis is based on the Kostant decomposition of simple Lie algebras in terms of representations with respect to their 'principal' SL(2) subalgebra. (author) 27 refs

  17. Norm of the Riemannian Curvature Tensor

    Indian Academy of Sciences (India)

    We consider the Riemannian functional R p ( g ) = ∫ M | R ( g ) | p d v g defined on the space of Riemannian metrics with unit volume on a closed smooth manifold where R ( g ) and d v g denote the corresponding Riemannian curvature tensor and volume form and p ∈ ( 0 , ∞ ) . First we prove that the Riemannian metrics ...

  18. Constraining inverse curvature gravity with supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Mena, Olga; Santiago, Jose; /Fermilab; Weller, Jochen; /University Coll., London /Fermilab

    2005-10-01

    We show that the current accelerated expansion of the Universe can be explained without resorting to dark energy. Models of generalized modified gravity, with inverse powers of the curvature can have late time accelerating attractors without conflicting with solar system experiments. We have solved the Friedman equations for the full dynamical range of the evolution of the Universe. This allows us to perform a detailed analysis of Supernovae data in the context of such models that results in an excellent fit. Hence, inverse curvature gravity models represent an example of phenomenologically viable models in which the current acceleration of the Universe is driven by curvature instead of dark energy. If we further include constraints on the current expansion rate of the Universe from the Hubble Space Telescope and on the age of the Universe from globular clusters, we obtain that the matter content of the Universe is 0.07 {le} {omega}{sub m} {le} 0.21 (95% Confidence). Hence the inverse curvature gravity models considered can not explain the dynamics of the Universe just with a baryonic matter component.

  19. On Mass, Spacetime Curvature, and Gravity

    Science.gov (United States)

    Janis, Allen I.

    2018-01-01

    The frequently used analogy of a massive ball distorting an elastic sheet, which is used to illustrate why mass causes spacetime curvature and gravitational attraction, is criticized in this article. A different analogy that draws on the students' previous knowledge of spacetime diagrams in special relativity is suggested.

  20. Curvature tensor copies in affine geometry

    International Nuclear Information System (INIS)

    Srivastava, P.P.

    1981-01-01

    The sets of space-time and spin-connections which give rise to the same curvature tensor are constructed. The corresponding geometries are compared. Results are illustrated by an explicit calculation and comment on the copies in Einstein-Cartan and Weyl-Cartan geometries. (Author) [pt

  1. Gaussian curvature on hyperelliptic Riemann surfaces

    Indian Academy of Sciences (India)

    Indian Acad. Sci. (Math. Sci.) Vol. 124, No. 2, May 2014, pp. 155–167. c Indian Academy of Sciences. Gaussian curvature on hyperelliptic Riemann surfaces. ABEL CASTORENA. Centro de Ciencias Matemáticas (Universidad Nacional Autónoma de México,. Campus Morelia) Apdo. Postal 61-3 Xangari, C.P. 58089 Morelia,.

  2. Resolving curvature singularities in holomorphic gravity

    NARCIS (Netherlands)

    Mantz, C.L.M.; Prokopec, T.

    2011-01-01

    We formulate a holomorphic theory of gravity and study how the holomorphy symmetry alters the two most important singular solutions of general relativity: black holes and cosmology. We show that typical observers (freely) falling into a holomorphic black hole do not encounter a curvature

  3. Curvature driven instabilities in toroidal plasmas

    International Nuclear Information System (INIS)

    Andersson, P.

    1986-11-01

    The electromagnetic ballooning mode, the curvature driven trapped electron mode and the toroidally induced ion temperature gradient mode have been studies. Eigenvalue equations have been derived and solved both numerically and analytically. For electromagnetic ballooning modes the effects of convective damping, finite Larmor radius, higher order curvature terms, and temperature gradients have been investigated. A fully toroidal fluid ion model has been developed. It is shown that a necessary and sufficient condition for an instability below the MHD limit is the presence of an ion temperature gradient. Analytical dispersion relations giving results in good agreement with numerical solutions are also presented. The curvature driven trapped electron modes are found to be unstable for virtually all parameters with growth rates of the order of the diamagnetic drift frequency. Studies have been made, using both a gyrokinetic ion description and the fully toroidal ion model. Both analytical and numerical results are presented and are found to be in good agreement. The toroidally induced ion temperature gradients modes are found to have a behavior similar to that of the curvature driven trapped electron modes and can in the electrostatic limit be described by a simple quadratic dispersion equation. (author)

  4. Random paths with curvature dependent action

    International Nuclear Information System (INIS)

    Ambjoern, J.; Durhuus, B.

    1986-11-01

    We study discretized random paths with a curvature dependent action. The scaling limits of the corresponding statistical mechanical models can be constructed explicitly and are either usual Brownian motion or a theory where the correlations of tangents are nonzero and described by diffusion on the unit sphere. In the latter case the two point function has an anomalous dimension η = 1. (orig.)

  5. Gaussian curvature elasticity determined from global shape transformations and local stress distributions : a comparative study using the MARTINI model

    NARCIS (Netherlands)

    Hu, Mingyang; de Jong, Djurre H.; Marrink, Siewert J.; Deserno, Markus

    2013-01-01

    We calculate the Gaussian curvature modulus (k) over bar of a systematically coarse-grained (CG) one-component lipid membrane by applying the method recently proposed by Hu et al. [Biophys. J., 2012, 102, 1403] to the MARTINI representation of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). We

  6. Sensitive zone parameters and curvature radius evaluation for polymer optical fiber curvature sensors

    Science.gov (United States)

    Leal-Junior, Arnaldo G.; Frizera, Anselmo; José Pontes, Maria

    2018-03-01

    Polymer optical fibers (POFs) are suitable for applications such as curvature sensors, strain, temperature, liquid level, among others. However, for enhancing sensitivity, many polymer optical fiber curvature sensors based on intensity variation require a lateral section. Lateral section length, depth, and surface roughness have great influence on the sensor sensitivity, hysteresis, and linearity. Moreover, the sensor curvature radius increase the stress on the fiber, which leads on variation of the sensor behavior. This paper presents the analysis relating the curvature radius and lateral section length, depth and surface roughness with the sensor sensitivity, hysteresis and linearity for a POF curvature sensor. Results show a strong correlation between the decision parameters behavior and the performance for sensor applications based on intensity variation. Furthermore, there is a trade-off among the sensitive zone length, depth, surface roughness, and curvature radius with the sensor desired performance parameters, which are minimum hysteresis, maximum sensitivity, and maximum linearity. The optimization of these parameters is applied to obtain a sensor with sensitivity of 20.9 mV/°, linearity of 0.9992 and hysteresis below 1%, which represent a better performance of the sensor when compared with the sensor without the optimization.

  7. A curvature theory for discrete surfaces based on mesh parallelity

    KAUST Repository

    Bobenko, Alexander Ivanovich; Pottmann, Helmut; Wallner, Johannes

    2009-01-01

    We consider a general theory of curvatures of discrete surfaces equipped with edgewise parallel Gauss images, and where mean and Gaussian curvatures of faces are derived from the faces' areas and mixed areas. Remarkably these notions are capable

  8. Phase separation in artificial vesicles driven by light and curvature

    Science.gov (United States)

    Rinaldin, Melissa; Pomp, Wim; Schmidt, Thomas; Giomi, Luca; Kraft, Daniela; Physics of Life Processes Team; Soft; Bio Mechanics Collaboration; Self-Assembly in Soft Matter Systems Collaboration

    The role of phase-demixing in living cells, leading to the lipid-raft hypothesis, has been extensively studied. Lipid domains of higher lipid chain order are proposed to regulate protein spatial organization. Giant Unilamellar Vesicles provide an artificial model to study phase separation. So far temperature was used to initiate the process. Here we introduce a new methodology based on the induction of phase separation by light. To this aim, the composition of the lipid membrane is varied by photo-oxidation of lipids. The control of the process gained by using light allowed us to observe vesicle shape fluctuations during phase-demixing. The presence of fluctuations near the critical mixing point resembles features of a critical process. We quantitatively analyze these fluctuations using a 2d elastic model, from which we can estimate the material parameters such as bending rigidity and surface tension, demonstrating the non-equilibrium critical behaviour. Finally, I will describe recent attempts toward tuning the membrane composition by controlling the vesicle curvature.

  9. Collineations of the curvature tensor in general relativity

    Indian Academy of Sciences (India)

    Curvature collineations for the curvature tensor, constructed from a fundamental Bianchi Type-V metric, are studied. We are concerned with a symmetry property of space-time which is called curvature collineation, and we briefly discuss the physical and kinematical properties of the models.

  10. Translating solitons to symplectic and Lagrangian mean curvature flows

    International Nuclear Information System (INIS)

    Han Xiaoli; Li Jiayu

    2007-05-01

    In this paper, we construct finite blow-up examples for symplectic mean curvature flows and we study symplectic translating solitons. We prove that there is no translating solitons with vertical bar α vertical bar ≤ α 0 to the symplectic mean curvature flow or to the almost calibrated Lagrangian mean curvature flow for some α 0 . (author)

  11. Integration of length and curvature in haptic perception

    NARCIS (Netherlands)

    Panday, V.; Bergmann Tiest, W.M.; Kappers, A.M.L.

    2014-01-01

    We investigated if and how length and curvature information are integrated when an object is explored in one hand. Subjects were asked to explore four types of objects between thumb and index finger. Objects differed in either length, curvature, both length and curvature correlated as in a circle,

  12. Weyl curvature tensor in static spherical sources

    International Nuclear Information System (INIS)

    Ponce de Leon, J.

    1988-01-01

    The role of the Weyl curvature tensor in static sources of the Schwarzschild field is studied. It is shown that in general the contribution from the Weyl curvature tensor (the ''purely gravitational field energy'') to the mass-energy inside the body may be positive, negative, or zero. It is proved that a positive (negative) contribution from the Weyl tensor tends to increase (decrease) the effective gravitational mass, the red-shift (from a point in the sphere to infinity), as well as the gravitational force which acts on a constituent matter element of a body. It is also proved that the contribution from the Weyl tensor always is negative in sources with surface gravitational potential larger than (4/9. It is pointed out that large negative contributions from the Weyl tensor could give rise to the phenomenon of gravitational repulsion. A simple example which illustrates the results is discussed

  13. Discrete Curvatures and Discrete Minimal Surfaces

    KAUST Repository

    Sun, Xiang

    2012-06-01

    This thesis presents an overview of some approaches to compute Gaussian and mean curvature on discrete surfaces and discusses discrete minimal surfaces. The variety of applications of differential geometry in visualization and shape design leads to great interest in studying discrete surfaces. With the rich smooth surface theory in hand, one would hope that this elegant theory can still be applied to the discrete counter part. Such a generalization, however, is not always successful. While discrete surfaces have the advantage of being finite dimensional, thus easier to treat, their geometric properties such as curvatures are not well defined in the classical sense. Furthermore, the powerful calculus tool can hardly be applied. The methods in this thesis, including angular defect formula, cotangent formula, parallel meshes, relative geometry etc. are approaches based on offset meshes or generalized offset meshes. As an important application, we discuss discrete minimal surfaces and discrete Koenigs meshes.

  14. On a curvature-statistics theorem

    International Nuclear Information System (INIS)

    Calixto, M; Aldaya, V

    2008-01-01

    The spin-statistics theorem in quantum field theory relates the spin of a particle to the statistics obeyed by that particle. Here we investigate an interesting correspondence or connection between curvature (κ = ±1) and quantum statistics (Fermi-Dirac and Bose-Einstein, respectively). The interrelation between both concepts is established through vacuum coherent configurations of zero modes in quantum field theory on the compact O(3) and noncompact O(2; 1) (spatial) isometry subgroups of de Sitter and Anti de Sitter spaces, respectively. The high frequency limit, is retrieved as a (zero curvature) group contraction to the Newton-Hooke (harmonic oscillator) group. We also make some comments on the physical significance of the vacuum energy density and the cosmological constant problem.

  15. On a curvature-statistics theorem

    Energy Technology Data Exchange (ETDEWEB)

    Calixto, M [Departamento de Matematica Aplicada y Estadistica, Universidad Politecnica de Cartagena, Paseo Alfonso XIII 56, 30203 Cartagena (Spain); Aldaya, V [Instituto de Astrofisica de Andalucia, Apartado Postal 3004, 18080 Granada (Spain)], E-mail: Manuel.Calixto@upct.es

    2008-08-15

    The spin-statistics theorem in quantum field theory relates the spin of a particle to the statistics obeyed by that particle. Here we investigate an interesting correspondence or connection between curvature ({kappa} = {+-}1) and quantum statistics (Fermi-Dirac and Bose-Einstein, respectively). The interrelation between both concepts is established through vacuum coherent configurations of zero modes in quantum field theory on the compact O(3) and noncompact O(2; 1) (spatial) isometry subgroups of de Sitter and Anti de Sitter spaces, respectively. The high frequency limit, is retrieved as a (zero curvature) group contraction to the Newton-Hooke (harmonic oscillator) group. We also make some comments on the physical significance of the vacuum energy density and the cosmological constant problem.

  16. Cosmological signatures of anisotropic spatial curvature

    International Nuclear Information System (INIS)

    Pereira, Thiago S.; Marugán, Guillermo A. Mena; Carneiro, Saulo

    2015-01-01

    If one is willing to give up the cherished hypothesis of spatial isotropy, many interesting cosmological models can be developed beyond the simple anisotropically expanding scenarios. One interesting possibility is presented by shear-free models in which the anisotropy emerges at the level of the curvature of the homogeneous spatial sections, whereas the expansion is dictated by a single scale factor. We show that such models represent viable alternatives to describe the large-scale structure of the inflationary universe, leading to a kinematically equivalent Sachs-Wolfe effect. Through the definition of a complete set of spatial eigenfunctions we compute the two-point correlation function of scalar perturbations in these models. In addition, we show how such scenarios would modify the spectrum of the CMB assuming that the observations take place in a small patch of a universe with anisotropic curvature

  17. Cosmological signatures of anisotropic spatial curvature

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Thiago S. [Departamento de Física, Universidade Estadual de Londrina, 86057-970, Londrina – PR (Brazil); Marugán, Guillermo A. Mena [Instituto de Estructura de la Materia, IEM-CSIC, Serrano 121, 28006, Madrid (Spain); Carneiro, Saulo, E-mail: tspereira@uel.br, E-mail: mena@iem.cfmac.csic.es, E-mail: saulo.carneiro@pq.cnpq.br [Instituto de Física, Universidade Federal da Bahia, 40210-340, Salvador – BA (Brazil)

    2015-07-01

    If one is willing to give up the cherished hypothesis of spatial isotropy, many interesting cosmological models can be developed beyond the simple anisotropically expanding scenarios. One interesting possibility is presented by shear-free models in which the anisotropy emerges at the level of the curvature of the homogeneous spatial sections, whereas the expansion is dictated by a single scale factor. We show that such models represent viable alternatives to describe the large-scale structure of the inflationary universe, leading to a kinematically equivalent Sachs-Wolfe effect. Through the definition of a complete set of spatial eigenfunctions we compute the two-point correlation function of scalar perturbations in these models. In addition, we show how such scenarios would modify the spectrum of the CMB assuming that the observations take place in a small patch of a universe with anisotropic curvature.

  18. The Riemann-Lovelock curvature tensor

    International Nuclear Information System (INIS)

    Kastor, David

    2012-01-01

    In order to study the properties of Lovelock gravity theories in low dimensions, we define the kth-order Riemann-Lovelock tensor as a certain quantity having a total 4k-indices, which is kth order in the Riemann curvature tensor and shares its basic algebraic and differential properties. We show that the kth-order Riemann-Lovelock tensor is determined by its traces in dimensions 2k ≤ D < 4k. In D = 2k + 1 this identity implies that all solutions of pure kth-order Lovelock gravity are 'Riemann-Lovelock' flat. It is verified that the static, spherically symmetric solutions of these theories, which are missing solid angle spacetimes, indeed satisfy this flatness property. This generalizes results from Einstein gravity in D = 3, which corresponds to the k = 1 case. We speculate about some possible further consequences of Riemann-Lovelock curvature. (paper)

  19. Harmonic curvatures and generalized helices in En

    International Nuclear Information System (INIS)

    Camci, Cetin; Ilarslan, Kazim; Kula, Levent; Hacisalihoglu, H. Hilmi

    2009-01-01

    In n-dimensional Euclidean space E n , harmonic curvatures of a non-degenerate curve defined by Ozdamar and Hacisalihoglu [Ozdamar E, Hacisalihoglu HH. A characterization of Inclined curves in Euclidean n-space. Comm Fac Sci Univ Ankara, Ser A1 1975;24:15-23]. In this paper, we give some characterizations for a non-degenerate curve α to be a generalized helix by using its harmonic curvatures. Also we define the generalized Darboux vector D of a non-degenerate curve α in n-dimensional Euclidean space E n and we show that the generalized Darboux vector D lies in the kernel of Frenet matrix M(s) if and only if the curve α is a generalized helix in the sense of Hayden.

  20. Gravitational curvature an introduction to Einstein's theory

    CERN Document Server

    Frankel, Theodore Thomas

    1979-01-01

    This classic text and reference monograph applies modern differential geometry to general relativity. A brief mathematical introduction to gravitational curvature, it emphasizes the subject's geometric essence, replacing the often-tedious analytical computations with geometric arguments. Clearly presented and physically motivated derivations express the deflection of light, Schwarzchild's exterior and interior solutions, and the Oppenheimer-Volkoff equations. A perfect choice for advanced students of mathematics, this volume will also appeal to mathematicians interested in physics. It stresses

  1. Curvature controlled wetting in two dimensions

    DEFF Research Database (Denmark)

    Gil, Tamir; Mikheev, Lev V.

    1995-01-01

    . As the radius of the substrate r0→∞, the leading effect of the curvature is adding the Laplace pressure ΠL∝r0-1 to the pressure balance in the film. At temperatures and pressures under which the wetting is complete in planar geometry, Laplace pressure suppresses divergence of the mean thickness of the wetting...... term reduces the thickness by the amount proportional to r0-1/3...

  2. The Riemann-Lovelock Curvature Tensor

    OpenAIRE

    Kastor, David

    2012-01-01

    In order to study the properties of Lovelock gravity theories in low dimensions, we define the kth-order Riemann-Lovelock tensor as a certain quantity having a total 4k-indices, which is kth-order in the Riemann curvature tensor and shares its basic algebraic and differential properties. We show that the kth-order Riemann-Lovelock tensor is determined by its traces in dimensions 2k \\le D

  3. Inflationary scenario from higher curvature warped spacetime

    International Nuclear Information System (INIS)

    Banerjee, Narayan; Paul, Tanmoy

    2017-01-01

    We consider a five dimensional warped spacetime, in presence of the higher curvature term like F(R) = R + αR 2 in the bulk, in the context of the two-brane model. Our universe is identified with the TeV scale brane and emerges as a four dimensional effective theory. From the perspective of this effective theory, we examine the possibility of ''inflationary scenario'' by considering the on-brane metric ansatz as an FRW one. Our results reveal that the higher curvature term in the five dimensional bulk spacetime generates a potential term for the radion field. Due to the presence of radion potential, the very early universe undergoes a stage of accelerated expansion and, moreover, the accelerating period of the universe terminates in a finite time. We also find the spectral index of curvature perturbation (n s ) and the tensor to scalar ratio (r) in the present context, which match with the observational results based on the observations of Planck (Astron. Astrophys. 594, A20, 2016). (orig.)

  4. Inflationary scenario from higher curvature warped spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, Narayan [Indian Institute of Science Education and Research Kolkata, Department of Physical Sciences, Nadia, West Bengal (India); Paul, Tanmoy [Indian Association for the Cultivation of Science, Department of Theoretical Physics, Kolkata (India)

    2017-10-15

    We consider a five dimensional warped spacetime, in presence of the higher curvature term like F(R) = R + αR{sup 2} in the bulk, in the context of the two-brane model. Our universe is identified with the TeV scale brane and emerges as a four dimensional effective theory. From the perspective of this effective theory, we examine the possibility of ''inflationary scenario'' by considering the on-brane metric ansatz as an FRW one. Our results reveal that the higher curvature term in the five dimensional bulk spacetime generates a potential term for the radion field. Due to the presence of radion potential, the very early universe undergoes a stage of accelerated expansion and, moreover, the accelerating period of the universe terminates in a finite time. We also find the spectral index of curvature perturbation (n{sub s}) and the tensor to scalar ratio (r) in the present context, which match with the observational results based on the observations of Planck (Astron. Astrophys. 594, A20, 2016). (orig.)

  5. Codimension two branes and distributional curvature

    International Nuclear Information System (INIS)

    Traschen, Jennie

    2009-01-01

    In general relativity, there is a well-developed formalism for working with the approximation that a gravitational source is concentrated on a shell, or codimension one surface. In contrast, there are obstacles to concentrating sources on surfaces that have a higher codimension, for example, a string in a spacetime with a dimension greater than or equal to four. Here it is shown that, by giving up some of the generality of the codimension one case, curvature can be concentrated on submanifolds that have codimension two. A class of metrics is identified such that (1) the scalar curvature and Ricci densities exist as distributions with support on a codimension two submanifold, and (2) using the Einstein equation, the distributional curvature corresponds to a concentrated stress-energy with equation of state p = -ρ, where p is the isotropic pressure tangent to the submanifold, and ρ is the energy density. This is the appropriate stress-energy to describe a self-gravitating brane that is governed by an area action, or a braneworld deSitter cosmology. The possibility of having a different equation of state arise from a wider class of metrics is discussed.

  6. Distributed mean curvature on a discrete manifold for Regge calculus

    International Nuclear Information System (INIS)

    Conboye, Rory; Miller, Warner A; Ray, Shannon

    2015-01-01

    The integrated mean curvature of a simplicial manifold is well understood in both Regge Calculus and Discrete Differential Geometry. However, a well motivated pointwise definition of curvature requires a careful choice of the volume over which to uniformly distribute the local integrated curvature. We show that hybrid cells formed using both the simplicial lattice and its circumcentric dual emerge as a remarkably natural structure for the distribution of this local integrated curvature. These hybrid cells form a complete tessellation of the simplicial manifold, contain a geometric orthonormal basis, and are also shown to give a pointwise mean curvature with a natural interpretation as the fractional rate of change of the normal vector. (paper)

  7. Distributed mean curvature on a discrete manifold for Regge calculus

    Science.gov (United States)

    Conboye, Rory; Miller, Warner A.; Ray, Shannon

    2015-09-01

    The integrated mean curvature of a simplicial manifold is well understood in both Regge Calculus and Discrete Differential Geometry. However, a well motivated pointwise definition of curvature requires a careful choice of the volume over which to uniformly distribute the local integrated curvature. We show that hybrid cells formed using both the simplicial lattice and its circumcentric dual emerge as a remarkably natural structure for the distribution of this local integrated curvature. These hybrid cells form a complete tessellation of the simplicial manifold, contain a geometric orthonormal basis, and are also shown to give a pointwise mean curvature with a natural interpretation as the fractional rate of change of the normal vector.

  8. A curvature theory for discrete surfaces based on mesh parallelity

    KAUST Repository

    Bobenko, Alexander Ivanovich

    2009-12-18

    We consider a general theory of curvatures of discrete surfaces equipped with edgewise parallel Gauss images, and where mean and Gaussian curvatures of faces are derived from the faces\\' areas and mixed areas. Remarkably these notions are capable of unifying notable previously defined classes of surfaces, such as discrete isothermic minimal surfaces and surfaces of constant mean curvature. We discuss various types of natural Gauss images, the existence of principal curvatures, constant curvature surfaces, Christoffel duality, Koenigs nets, contact element nets, s-isothermic nets, and interesting special cases such as discrete Delaunay surfaces derived from elliptic billiards. © 2009 Springer-Verlag.

  9. Integration of length and curvature in haptic perception.

    Science.gov (United States)

    Panday, Virjanand; Tiest, Wouter M Bergmann; Kappers, Astrid M L

    2014-01-24

    We investigated if and how length and curvature information are integrated when an object is explored in one hand. Subjects were asked to explore four types of objects between thumb and index finger. Objects differed in either length, curvature, both length and curvature correlated as in a circle, or anti-correlated. We found that when both length and curvature are present, performance is significantly better than when only one of the two cues is available. Therefore, we conclude that there is integration of length and curvature. Moreover, if the two cues are correlated in a circular cross-section instead of in an anti-correlated way, performance is better than predicted by a combination of two independent cues. We conclude that integration of curvature and length is highly efficient when the cues in the object are combined as in a circle, which is the most common combination of curvature and length in daily life.

  10. Zero curvature-surface driven small objects

    Science.gov (United States)

    Dou, Xiaoxiao; Li, Shanpeng; Liu, Jianlin

    2017-08-01

    In this study, we investigate the spontaneous migration of small objects driven by surface tension on a catenoid, formed by a layer of soap constrained by two rings. Although the average curvature of the catenoid is zero at each point, the small objects always migrate to the position near the ring. The force and energy analyses have been performed to uncover the mechanism, and it is found that the small objects distort the local shape of the liquid film, thus making the whole system energetically favorable. These findings provide some inspiration to design microfluidics, aquatic robotics, and miniature boats.

  11. Spacetime Curvature and Higgs Stability after Inflation.

    Science.gov (United States)

    Herranen, M; Markkanen, T; Nurmi, S; Rajantie, A

    2015-12-11

    We investigate the dynamics of the Higgs field at the end of inflation in the minimal scenario consisting of an inflaton field coupled to the standard model only through the nonminimal gravitational coupling ξ of the Higgs field. Such a coupling is required by renormalization of the standard model in curved space, and in the current scenario also by vacuum stability during high-scale inflation. We find that for ξ≳1, rapidly changing spacetime curvature at the end of inflation leads to significant production of Higgs particles, potentially triggering a transition to a negative-energy Planck scale vacuum state and causing an immediate collapse of the Universe.

  12. Constraining inverse-curvature gravity with supernovae.

    Science.gov (United States)

    Mena, Olga; Santiago, José; Weller, Jochen

    2006-02-03

    We show that models of generalized modified gravity, with inverse powers of the curvature, can explain the current accelerated expansion of the Universe without resorting to dark energy and without conflicting with solar system experiments. We have solved the Friedmann equations for the full dynamical range of the evolution of the Universe and performed a detailed analysis of supernovae data in the context of such models that results in an excellent fit. If we further include constraints on the current expansion of the Universe and on its age, we obtain that the matter content of the Universe is 0.07baryonic matter component.

  13. Amplification of curvature perturbations in cyclic cosmology

    International Nuclear Information System (INIS)

    Zhang Jun; Liu Zhiguo; Piao Yunsong

    2010-01-01

    We analytically and numerically show that through the cycles with nonsingular bounce, the amplitude of curvature perturbation on a large scale will be amplified and the power spectrum will redden. In some sense, this amplification will eventually destroy the homogeneity of the background, which will lead to the ultimate end of cycles of the global universe. We argue that for the model with increasing cycles, it might be possible that a fissiparous multiverse will emerge after one or several cycles, in which the cycles will continue only at corresponding local regions.

  14. Curvature, zero modes and quantum statistics

    Energy Technology Data Exchange (ETDEWEB)

    Calixto, M [Departamento de Matematica Aplicada y EstadIstica, Universidad Politecnica de Cartagena, Paseo Alfonso XIII 56, 30203 Cartagena (Spain); Aldaya, V [Instituto de AstrofIsica de AndalucIa, Apartado Postal 3004, 18080 Granada (Spain)

    2006-08-18

    We explore an intriguing connection between the Fermi-Dirac and Bose-Einstein statistics and the thermal baths obtained from a vacuum radiation of coherent states of zero modes in a second quantized (many-particle) theory on the compact O(3) and noncompact O(2, 1) isometry subgroups of the de Sitter and anti-de Sitter spaces, respectively. The high frequency limit is retrieved as a (zero-curvature) group contraction to the Newton-Hooke (harmonic oscillator) group. We also make some comments on the vacuum energy density and the cosmological constant problem. (letter to the editor)

  15. Differential geometry bundles, connections, metrics and curvature

    CERN Document Server

    Taubes, Clifford Henry

    2011-01-01

    Bundles, connections, metrics and curvature are the 'lingua franca' of modern differential geometry and theoretical physics. This book will supply a graduate student in mathematics or theoretical physics with the fundamentals of these objects. Many of the tools used in differential topology are introduced and the basic results about differentiable manifolds, smooth maps, differential forms, vector fields, Lie groups, and Grassmanians are all presented here. Other material covered includes the basic theorems about geodesics and Jacobi fields, the classification theorem for flat connections, the

  16. Curvature and temperature of complex networks.

    Science.gov (United States)

    Krioukov, Dmitri; Papadopoulos, Fragkiskos; Vahdat, Amin; Boguñá, Marián

    2009-09-01

    We show that heterogeneous degree distributions in observed scale-free topologies of complex networks can emerge as a consequence of the exponential expansion of hidden hyperbolic space. Fermi-Dirac statistics provides a physical interpretation of hyperbolic distances as energies of links. The hidden space curvature affects the heterogeneity of the degree distribution, while clustering is a function of temperature. We embed the internet into the hyperbolic plane and find a remarkable congruency between the embedding and our hyperbolic model. Besides proving our model realistic, this embedding may be used for routing with only local information, which holds significant promise for improving the performance of internet routing.

  17. Polarized curvature radiation in pulsar magnetosphere

    Science.gov (United States)

    Wang, P. F.; Wang, C.; Han, J. L.

    2014-07-01

    The propagation of polarized emission in pulsar magnetosphere is investigated in this paper. The polarized waves are generated through curvature radiation from the relativistic particles streaming along curved magnetic field lines and corotating with the pulsar magnetosphere. Within the 1/γ emission cone, the waves can be divided into two natural wave-mode components, the ordinary (O) mode and the extraordinary (X) mode, with comparable intensities. Both components propagate separately in magnetosphere, and are aligned within the cone by adiabatic walking. The refraction of O mode makes the two components separated and incoherent. The detectable emission at a given height and a given rotation phase consists of incoherent X-mode and O-mode components coming from discrete emission regions. For four particle-density models in the form of uniformity, cone, core and patches, we calculate the intensities for each mode numerically within the entire pulsar beam. If the corotation of relativistic particles with magnetosphere is not considered, the intensity distributions for the X-mode and O-mode components are quite similar within the pulsar beam, which causes serious depolarization. However, if the corotation of relativistic particles is considered, the intensity distributions of the two modes are very different, and the net polarization of outcoming emission should be significant. Our numerical results are compared with observations, and can naturally explain the orthogonal polarization modes of some pulsars. Strong linear polarizations of some parts of pulsar profile can be reproduced by curvature radiation and subsequent propagation effect.

  18. Emergent gravity in spaces of constant curvature

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, Orlando; Haddad, Matthew [Department of Physics, University of Miami,1320 Campo Sano Ave, Coral Gables, FL 33146 (United States)

    2017-03-07

    In physical theories where the energy (action) is localized near a submanifold of a constant curvature space, there is a universal expression for the energy (or the action). We derive a multipole expansion for the energy that has a finite number of terms, and depends on intrinsic geometric invariants of the submanifold and extrinsic invariants of the embedding of the submanifold. This is the second of a pair of articles in which we try to develop a theory of emergent gravity arising from the embedding of a submanifold into an ambient space equipped with a quantum field theory. Our theoretical method requires a generalization of a formula due to by Hermann Weyl. While the first paper discussed the framework in Euclidean (Minkowski) space, here we discuss how this framework generalizes to spaces of constant sectional curvature. We focus primarily on anti de Sitter space. We then discuss how such a theory can give rise to a cosmological constant and Planck mass that are within reasonable bounds of the experimental values.

  19. Gas separation membranes

    Science.gov (United States)

    Schell, William J.

    1979-01-01

    A dry, fabric supported, polymeric gas separation membrane, such as cellulose acetate, is prepared by casting a solution of the polymer onto a shrinkable fabric preferably formed of synthetic polymers such as polyester or polyamide filaments before washing, stretching or calendering (so called griege goods). The supported membrane is then subjected to gelling, annealing, and drying by solvent exchange. During the processing steps, both the fabric support and the membrane shrink a preselected, controlled amount which prevents curling, wrinkling or cracking of the membrane in flat form or when spirally wound into a gas separation element.

  20. Lecture notes on mean curvature flow, barriers and singular perturbations

    CERN Document Server

    Bellettini, Giovanni

    2013-01-01

    The aim of the book is to study some aspects of geometric evolutions, such as mean curvature flow and anisotropic mean curvature flow of hypersurfaces. We analyze the origin of such flows and their geometric and variational nature. Some of the most important aspects of mean curvature flow are described, such as the comparison principle and its use in the definition of suitable weak solutions. The anisotropic evolutions, which can be considered as a generalization of mean curvature flow, are studied from the view point of Finsler geometry. Concerning singular perturbations, we discuss the convergence of the Allen–Cahn (or Ginsburg–Landau) type equations to (possibly anisotropic) mean curvature flow before the onset of singularities in the limit problem. We study such kinds of asymptotic problems also in the static case, showing convergence to prescribed curvature-type problems.

  1. The curvature calculation mechanism based on simple cell model.

    Science.gov (United States)

    Yu, Haiyang; Fan, Xingyu; Song, Aiqi

    2017-07-20

    A conclusion has not yet been reached on how exactly the human visual system detects curvature. This paper demonstrates how orientation-selective simple cells can be used to construct curvature-detecting neural units. Through fixed arrangements, multiple plurality cells were constructed to simulate curvature cells with a proportional output to their curvature. In addition, this paper offers a solution to the problem of narrow detection range under fixed resolution by selecting an output value under multiple resolution. Curvature cells can be treated as concrete models of an end-stopped mechanism, and they can be used to further understand "curvature-selective" characteristics and to explain basic psychophysical findings and perceptual phenomena in current studies.

  2. On Riemannian manifolds (Mn, g) of quasi-constant curvature

    International Nuclear Information System (INIS)

    Rahman, M.S.

    1995-07-01

    A Riemannian manifold (M n , g) of quasi-constant curvature is defined. It is shown that an (M n , g) in association with other class of manifolds gives rise, under certain conditions, to a manifold of quasi-constant curvature. Some observations on how a manifold of quasi-constant curvature accounts for a pseudo Ricci-symmetric manifold and quasi-umbilical hypersurface are made. (author). 10 refs

  3. Statistical mechanics of paths with curvature dependent action

    International Nuclear Information System (INIS)

    Ambjoern, J.; Durhuus, B.; Jonsson, T.

    1987-01-01

    We analyze the scaling limit of discretized random paths with curvature dependent action. For finite values of the curvature coupling constant the theory belongs to the universality class of simple random walk. It is possible to define a non-trivial scaling limit if the curvature coupling tends to infinity. We compute exactly the two point function in this limit and discuss the relevance of our results for random surfaces and string theories. (orig.)

  4. Evolution of the curvature perturbations during warm inflation

    International Nuclear Information System (INIS)

    Matsuda, Tomohiro

    2009-01-01

    This paper considers warm inflation as an interesting application of multi-field inflation. Delta-N formalism is used for the calculation of the evolution of the curvature perturbations during warm inflation. Although the perturbations considered in this paper are decaying after the horizon exit, the corrections to the curvature perturbations sourced by these perturbations can remain and dominate the curvature perturbations at large scales. In addition to the typical evolution of the curvature perturbations, inhomogeneous diffusion rate is considered for warm inflation, which may lead to significant non-Gaussianity of the spectrum

  5. 3D face recognition with asymptotic cones based principal curvatures

    KAUST Repository

    Tang, Yinhang; Sun, Xiang; Huang, Di; Morvan, Jean-Marie; Wang, Yunhong; Chen, Liming

    2015-01-01

    The classical curvatures of smooth surfaces (Gaussian, mean and principal curvatures) have been widely used in 3D face recognition (FR). However, facial surfaces resulting from 3D sensors are discrete meshes. In this paper, we present a general framework and define three principal curvatures on discrete surfaces for the purpose of 3D FR. These principal curvatures are derived from the construction of asymptotic cones associated to any Borel subset of the discrete surface. They describe the local geometry of the underlying mesh. First two of them correspond to the classical principal curvatures in the smooth case. We isolate the third principal curvature that carries out meaningful geometric shape information. The three principal curvatures in different Borel subsets scales give multi-scale local facial surface descriptors. We combine the proposed principal curvatures with the LNP-based facial descriptor and SRC for recognition. The identification and verification experiments demonstrate the practicability and accuracy of the third principal curvature and the fusion of multi-scale Borel subset descriptors on 3D face from FRGC v2.0.

  6. Robust estimation of adaptive tensors of curvature by tensor voting.

    Science.gov (United States)

    Tong, Wai-Shun; Tang, Chi-Keung

    2005-03-01

    Although curvature estimation from a given mesh or regularly sampled point set is a well-studied problem, it is still challenging when the input consists of a cloud of unstructured points corrupted by misalignment error and outlier noise. Such input is ubiquitous in computer vision. In this paper, we propose a three-pass tensor voting algorithm to robustly estimate curvature tensors, from which accurate principal curvatures and directions can be calculated. Our quantitative estimation is an improvement over the previous two-pass algorithm, where only qualitative curvature estimation (sign of Gaussian curvature) is performed. To overcome misalignment errors, our improved method automatically corrects input point locations at subvoxel precision, which also rejects outliers that are uncorrectable. To adapt to different scales locally, we define the RadiusHit of a curvature tensor to quantify estimation accuracy and applicability. Our curvature estimation algorithm has been proven with detailed quantitative experiments, performing better in a variety of standard error metrics (percentage error in curvature magnitudes, absolute angle difference in curvature direction) in the presence of a large amount of misalignment noise.

  7. 3D face recognition with asymptotic cones based principal curvatures

    KAUST Repository

    Tang, Yinhang

    2015-05-01

    The classical curvatures of smooth surfaces (Gaussian, mean and principal curvatures) have been widely used in 3D face recognition (FR). However, facial surfaces resulting from 3D sensors are discrete meshes. In this paper, we present a general framework and define three principal curvatures on discrete surfaces for the purpose of 3D FR. These principal curvatures are derived from the construction of asymptotic cones associated to any Borel subset of the discrete surface. They describe the local geometry of the underlying mesh. First two of them correspond to the classical principal curvatures in the smooth case. We isolate the third principal curvature that carries out meaningful geometric shape information. The three principal curvatures in different Borel subsets scales give multi-scale local facial surface descriptors. We combine the proposed principal curvatures with the LNP-based facial descriptor and SRC for recognition. The identification and verification experiments demonstrate the practicability and accuracy of the third principal curvature and the fusion of multi-scale Borel subset descriptors on 3D face from FRGC v2.0.

  8. Hair curvature: a natural dialectic and review.

    Science.gov (United States)

    Nissimov, Joseph N; Das Chaudhuri, Asit Baran

    2014-08-01

    Although hair forms (straight, curly, wavy, etc.) are present in apparently infinite variations, each fibre can be reduced to a finite sequence of tandem segments of just three types: straight, bent/curly, or twisted. Hair forms can thus be regarded as resulting from genetic pathways that induce, reverse or modulate these basic curvature modes. However, physical interconversions between twists and curls demonstrate that strict one-to-one correspondences between them and their genetic causes do not exist. Current hair-curvature theories do not distinguish between bending and twisting mechanisms. We here introduce a multiple papillary centres (MPC) model which is particularly suitable to explain twisting. The model combines previously known features of hair cross-sectional morphology with partially/completely separated dermal papillae within single follicles, and requires such papillae to induce differential growth rates of hair cortical material in their immediate neighbourhoods. The MPC model can further help to explain other, poorly understood, aspects of hair growth and morphology. Separate bending and twisting mechanisms would be preferentially affected at the major or minor ellipsoidal sides of fibres, respectively, and together they exhaust the possibilities for influencing hair-form phenotypes. As such they suggest dialectic for hair-curvature development. We define a natural-dialectic (ND) which could take advantage of speculative aspects of dialectic, but would verify its input data and results by experimental methods. We use this as a top-down approach to first define routes by which hair bending or twisting may be brought about and then review evidence in support of such routes. In particular we consider the wingless (Wnt) and mammalian target of rapamycin (mTOR) pathways as paradigm pathways for molecular hair bending and twisting mechanisms, respectively. In addition to the Wnt canonical pathway, the Wnt/Ca(2+) and planar cell polarity (PCP) pathways

  9. Instagram Likes for Architectural Photos Can Be Predicted by Quantitative Balance Measures and Curvature

    Directory of Open Access Journals (Sweden)

    Katja Thömmes

    2018-06-01

    Full Text Available “3,058 people like this.” In the digital age, people very commonly indicate their preferences by clicking a Like button. The data generated on the photo-sharing platform Instagram potentially represents a vast, freely accessible resource for research in the field of visual experimental aesthetics. Therefore, we compiled a photo database using images of five different Instagram accounts that fullfil several criteria (e.g., large followership, consistent content. The final database consists of about 700 architectural photographs with the corresponding liking data generated by the Instagram community. First, we aimed at validating Instagram Likes as a potential measure of aesthetic appeal. Second, we checked whether previously studied low-level features of “good” image composition also account for the number of Instagram Likes that architectural photographs received. We considered two measures of visual balance and the preference for curvature over angularity. In addition, differences between images with “2D” vs. “3D” appearance became obvious. Our findings show that visual balance predicts Instagram Likes in more complex “3D” photographs, with more balance meaning more Likes. In the less complex “2D” photographs the relation is reversed, more balance led to fewer Likes. Moreover, there was a general preference for curvature in the Instagram database. Together, our study illustrates the potential of using Instagram Likes as a measure of aesthetic appeal and provides a fruitful methodological basis for future research.

  10. Hawking temperature of constant curvature black holes

    International Nuclear Information System (INIS)

    Cai Ronggen; Myung, Yun Soo

    2011-01-01

    The constant curvature (CC) black holes are higher dimensional generalizations of Banados-Teitelboim-Zanelli black holes. It is known that these black holes have the unusual topology of M D-1 xS 1 , where D is the spacetime dimension and M D-1 stands for a conformal Minkowski spacetime in D-1 dimensions. The unusual topology and time-dependence for the exterior of these black holes cause some difficulties to derive their thermodynamic quantities. In this work, by using a globally embedding approach, we obtain the Hawking temperature of the CC black holes. We find that the Hawking temperature takes the same form when using both the static and global coordinates. Also, it is identical to the Gibbons-Hawking temperature of the boundary de Sitter spaces of these CC black holes.

  11. Differential geometry connections, curvature, and characteristic classes

    CERN Document Server

    Tu, Loring W

    2017-01-01

    This text presents a graduate-level introduction to differential geometry for mathematics and physics students. The exposition follows the historical development of the concepts of connection and curvature with the goal of explaining the Chern–Weil theory of characteristic classes on a principal bundle. Along the way we encounter some of the high points in the history of differential geometry, for example, Gauss' Theorema Egregium and the Gauss–Bonnet theorem. Exercises throughout the book test the reader’s understanding of the material and sometimes illustrate extensions of the theory. Initially, the prerequisites for the reader include a passing familiarity with manifolds. After the first chapter, it becomes necessary to understand and manipulate differential forms. A knowledge of de Rham cohomology is required for the last third of the text. Prerequisite material is contained in author's text An Introduction to Manifolds, and can be learned in one semester. For the benefit of the reader and to establ...

  12. Curvature radiation by bunches of particles

    International Nuclear Information System (INIS)

    Saggion, A.

    1975-01-01

    A bunch of relativistic particles moving on a curved trajectory is considered. The coherent emission of curvature radiation is described with particular regard to the role played by the 'shape' of the bunch as a function of its dimensions. It is found that the length of the bunch strongly affects the spectrum of the radiation emitted, with no effect on its polarization. For wavelengths shorter than the length of the bunch, the emitted intensity as a function of frequency shows recurrent maxima and minima, the height of the maxima being proportional to νsup(-5/3). The bunch dimensions perpendicular to the plane of the orbit affect both the spectral intensity and the polarization of the radiation. (orig./BJ) [de

  13. Natural curvature for manifest T-duality

    International Nuclear Information System (INIS)

    Poláček, Martin; Siegel, Warren

    2014-01-01

    We reformulate the manifestly T-dual description of the massless sector of the closed bosonic string, directly from the geometry associated with the (left and right) affine Lie algebra of the coset space Poincaré/Lorentz. This construction initially doubles not only the (spacetime) coordinates for translations but also those for Lorentz transformations (and their “dual”). As a result, the Lorentz connection couples directly to the string (as does the vielbein), rather than being introduced ad hoc to the covariant derivative as previously. This not only reproduces the old definition of T-dual torsion, but automatically gives a general, covariant definition of T-dual curvature (but still with some undetermined connections)

  14. Nonminimal coupling of perfect fluids to curvature

    International Nuclear Information System (INIS)

    Bertolami, Orfeu; Lobo, Francisco S. N.; Paramos, Jorge

    2008-01-01

    In this work, we consider different forms of relativistic perfect fluid Lagrangian densities that yield the same gravitational field equations in general relativity (GR). A particularly intriguing example is the case with couplings of the form [1+f 2 (R)]L m , where R is the scalar curvature, which induces an extra force that depends on the form of the Lagrangian density. It has been found that, considering the Lagrangian density L m =p, where p is the pressure, the extra-force vanishes. We argue that this is not the unique choice for the matter Lagrangian density, and that more natural forms for L m do not imply the vanishing of the extra force. Particular attention is paid to the impact on the classical equivalence between different Lagrangian descriptions of a perfect fluid.

  15. Topological photonic crystals with zero Berry curvature

    Science.gov (United States)

    Liu, Feng; Deng, Hai-Yao; Wakabayashi, Katsunori

    2018-02-01

    Topological photonic crystals are designed based on the concept of Zak's phase rather than the topological invariants such as the Chern number and spin Chern number, which rely on the existence of a nonvanishing Berry curvature. Our photonic crystals (PCs) are made of pure dielectrics and sit on a square lattice obeying the C4 v point-group symmetry. Two varieties of PCs are considered: one closely resembles the electronic two-dimensional Su-Schrieffer-Heeger model, and the other continues as an extension of this analogy. In both cases, the topological transitions are induced by adjusting the lattice constants. Topological edge modes (TEMs) are shown to exist within the nontrivial photonic band gaps on the termination of those PCs. The high efficiency of these TEMs transferring electromagnetic energy against several types of disorders has been demonstrated using the finite-element method.

  16. A Field Theory with Curvature and Anticurvature

    Directory of Open Access Journals (Sweden)

    M. I. Wanas

    2014-01-01

    Full Text Available The present work is an attempt to construct a unified field theory in a space with curvature and anticurvature, the PAP-space. The theory is derived from an action principle and a Lagrangian density using a symmetric linear parameterized connection. Three different methods are used to explore physical contents of the theory obtained. Poisson’s equations for both material and charge distributions are obtained, as special cases, from the field equations of the theory. The theory is a pure geometric one in the sense that material distribution, charge distribution, gravitational and electromagnetic potentials, and other physical quantities are defined in terms of pure geometric objects of the structure used. In the case of pure gravity in free space, the spherical symmetric solution of the field equations gives the Schwarzschild exterior field. The weak equivalence principle is respected only in the case of pure gravity in free space; otherwise it is violated.

  17. Ion-conducting membranes

    Science.gov (United States)

    Masel, Richard I.; Sajjad, Syed Dawar; Gao, Yan; Liu, Zengcai; Chen, Qingmei

    2017-12-26

    An anion-conducting polymeric membrane comprises a terpolymer of styrene, vinylbenzyl-R.sub.s and vinylbenzyl-R.sub.x. R.sub.s is a positively charged cyclic amine group. R.sub.x is at least one constituent selected from the group consisting Cl, OH and a reaction product between an OH or Cl and a species other than a simple amine or a cyclic amine. The total weight of the vinylbenzyl-R.sub.x groups is greater than 0.3% of the total weight of the membrane. In a preferred embodiment, the membrane is a Helper Membrane that increases the faradaic efficiency of an electrochemical cell into which the membrane is incorporated, and also allows product formation at lower voltages than in cells without the Helper Membrane.

  18. Fine-Tuning of Photosynthesis Requires CURVATURE THYLAKOID1-Mediated Thylakoid Plasticity

    DEFF Research Database (Denmark)

    Pribil, Mathias; Sandoval Ibáñez, Omar Alejandro; Xu, Wenteng

    2018-01-01

    ultrastructure in Arabidopsis (Arabidopsis thaliana) reduces photosynthetic efficiency and plant fitness under adverse, controlled, and natural light conditions. Plants that lack CURT1 show less adjustment of grana diameter, which compromises regulatory mechanisms like the photosystem II repair cycle and state...... transitions. Interestingly, CURT1A suffices to induce thylakoid membrane curvature in planta and thylakoid hyperbending in plants overexpressing CURT1A. We suggest that CURT1 oligomerization is regulated at the posttranslational level in a light-dependent fashion and that CURT1-mediated thylakoid plasticity...

  19. Social preferences

    DEFF Research Database (Denmark)

    Gulløv, Eva

    2014-01-01

    The focus of this article is social divisions among preschool children in daycare centers. Based on ethnographic fieldwork in three daycare centers in Denmark, the analysis concerns young children’s social preferences. The ethnographic material shows that despite an explicit political ambition...... of daycares as means for social and cultural integration, lines of division do exist amongst the children. Such divisions are established in the daily interactions of the daycare, but they also reflect those of the broader society. With a focus on children’s interactions and social preferences, the material...... indicates that children’s choices of playmates run along lines of ethnic and class divisions. The article will address this pattern and analyze its causes in order to understand why such lines of divisions are to be found in an institutional context designed to overcome social inequality and prevent social...

  20. Clinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.

    Directory of Open Access Journals (Sweden)

    Yong Woo Kim

    Full Text Available Quantitative evaluation of lamina cribrosa (LC posterior bowing in primary open-angle glaucoma (POAG eyes using swept-source optical coherence tomography.Patients with POAG (n = 123 eyes and healthy individuals of a similar age (n = 92 eyes were prospectively recruited. Anterior laminar insertion depth (ALID was defined as the vertical distance between the anterior laminar insertion and a reference plane connecting the Bruch's membrane openings (BMO. The mean LC depth (mLCD was approximated by dividing the area enclosed by the anterior LC, the BMO reference plane, and the two vertical lines for ALID measurement by the length between those two vertical lines. The LC curvature index was defined as the difference between the mLCD and the ALID. The factors influencing the LC curvature index were evaluated.The ALID and mLCD were significantly larger in POAG eyes than in healthy controls (P -6 dB and moderate-to-advanced glaucoma (MD < -6 dB, P = 0.95.LC posterior bowing was increased in POAG eyes, and was significantly associated with structural optic nerve head (ONH changes but not with functional glaucoma severity. Quantitative evaluation of LC curvature can facilitate assessment of glaucomatous ONH change.

  1. Dual curvature acoustically damped concentrating collector. Semiannual technical progress report, June 1-December 1, 1978

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-12-01

    The project's first objective is to establish, analytically, the cost and performance of design choices within the boundaries of the basic proposed concept. With these cost and performance measures as a guide, the second project objective is to design a cost-effective Dual Curvature collector module and collector field array. The third objective is to establish technical and economic concept feasibility through prototype fabrication and test. The final objective is to define the Dual Curvature collector commercialization requirements. The Dual Curvature collector uses a unique reflector module consisting of a reflective film that is tensioned on a reflector support frame. The tensioned membrane (film) surface approximates a hyperbolic paraboloid that is capable of linear focusing when the surface tracks the sun's apparent motion in one axis. The reflective film can be backed by polystyrene foam with an air space between the film and the foam surfaces. This provides damping of the reflector surface to minimize the effect of wind gusts and physical impacts. The baseline collector is intended to operate at a concentration of ten (10) or greater with a nominal absorber temperature of 150/sup 0/C (300/sup 0/F). The Component Research and Analysis tasks which lead to the selection of a baseline collector configuration are discussed. Also, some preliminary results of the Collector Module Design task are presented.

  2. On harmonic curvatures of a Frenet curve in Lorentzian space

    International Nuclear Information System (INIS)

    Kuelahci, Mihriban; Bektas, Mehmet; Erguet, Mahmut

    2009-01-01

    In this paper, we consider curves of AW(k)-type, 1 ≤ k ≤ 3, in Lorentzian space. We give curvature conditions of these kind of curves. Furthermore, we study harmonic curvatures of curves of AW(k)-type. We investigate that under what conditions AW(k)-type curves are helix. Some related theorems and corollaries are also proved.

  3. The scalar curvature problem on the four dimensional half sphere

    CERN Document Server

    Ben-Ayed, M; El-Mehdi, K

    2003-01-01

    In this paper, we consider the problem of prescribing the scalar curvature under minimal boundary conditions on the standard four dimensional half sphere. We provide an Euler-Hopf type criterion for a given function to be a scalar curvature for some metric conformal to the standard one. Our proof involves the study of critical points at infinity of the associated variational problem.

  4. Statistical mechanics of surfaces with curvature dependent action

    International Nuclear Information System (INIS)

    Jonsson, T.

    1987-01-01

    We review recent results about discretized random surfaces whose action (energy) depends on the extrinsic curvature. The surface tension scales to zero at an appropriate critical point if the coupling constant of the curvature term is taken to infinity. At this critical point one expects to be able to construct a continuum theory of smooth surfaces. (orig.)

  5. Curvature of random walks and random polygons in confinement

    International Nuclear Information System (INIS)

    Diao, Y; Ernst, C; Montemayor, A; Ziegler, U

    2013-01-01

    The purpose of this paper is to study the curvature of equilateral random walks and polygons that are confined in a sphere. Curvature is one of several basic geometric properties that can be used to describe random walks and polygons. We show that confinement affects curvature quite strongly, and in the limit case where the confinement diameter equals the edge length the unconfined expected curvature value doubles from π/2 to π. To study curvature a simple model of an equilateral random walk in spherical confinement in dimensions 2 and 3 is introduced. For this simple model we derive explicit integral expressions for the expected value of the total curvature in both dimensions. These expressions are functions that depend only on the radius R of the confinement sphere. We then show that the values obtained by numeric integration of these expressions agrees with numerical average curvature estimates obtained from simulations of random walks. Finally, we compare the confinement effect on curvature of random walks with random polygons. (paper)

  6. Curvature collineations for the field of gravitational waves

    International Nuclear Information System (INIS)

    Singh, K.P.; Singh, Gulab

    1981-01-01

    It has been shown that the space-times formed from a plane-fronted gravity wave and from a plane sandwich wave with constant polarisation admit proper curvature collineation in general. The curvature collineation vectors have been determined explicitly. (author)

  7. Robust modal curvature features for identifying multiple damage in beams

    Science.gov (United States)

    Ostachowicz, Wiesław; Xu, Wei; Bai, Runbo; Radzieński, Maciej; Cao, Maosen

    2014-03-01

    Curvature mode shape is an effective feature for damage detection in beams. However, it is susceptible to measurement noise, easily impairing its advantage of sensitivity to damage. To deal with this deficiency, this study formulates an improved curvature mode shape for multiple damage detection in beams based on integrating a wavelet transform (WT) and a Teager energy operator (TEO). The improved curvature mode shape, termed the WT - TEO curvature mode shape, has inherent capabilities of immunity to noise and sensitivity to damage. The proposed method is experimentally validated by identifying multiple cracks in cantilever steel beams with the mode shapes acquired using a scanning laser vibrometer. The results demonstrate that the improved curvature mode shape can identify multiple damage accurately and reliably, and it is fairly robust to measurement noise.

  8. INVESTIGATION OF CURVES SET BY CUBIC DISTRIBUTION OF CURVATURE

    Directory of Open Access Journals (Sweden)

    S. A. Ustenko

    2014-03-01

    Full Text Available Purpose. Further development of the geometric modeling of curvelinear contours of different objects based on the specified cubic curvature distribution and setpoints of curvature in the boundary points. Methodology. We investigate the flat section of the curvilinear contour generating under condition that cubic curvature distribution is set. Curve begins and ends at the given points, where angles of tangent slope and curvature are also determined. It was obtained the curvature equation of this curve, depending on the section length and coefficient c of cubic curvature distribution. The analysis of obtained equation was carried out. As well as, it was investigated the conditions, in which the inflection points of the curve are appearing. One should find such an interval of parameter change (depending on the input data and the section length, in order to place the inflection point of the curvature graph outside the curve section borders. It was determined the dependence of tangent slope of angle to the curve at its arbitrary point, as well as it was given the recommendations to solve a system of integral equations that allow finding the length of the curve section and the coefficient c of curvature cubic distribution. Findings. As the result of curves research, it is found that the criterion for their selection one can consider the absence of inflection points of the curvature on the observed section. Influence analysis of the parameter c on the graph of tangent slope angle to the curve showed that regardless of its value, it is provided the same rate of angle increase of tangent slope to the curve. Originality. It is improved the approach to geometric modeling of curves based on cubic curvature distribution with its given values at the boundary points by eliminating the inflection points from the observed section of curvilinear contours. Practical value. Curves obtained using the proposed method can be used for geometric modeling of curvilinear

  9. Haptic perception of object curvature in Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Jürgen Konczak

    2008-07-01

    Full Text Available The haptic perception of the curvature of an object is essential for adequate object manipulation and critical for our guidance of actions. This study investigated how the ability to perceive the curvature of an object is altered by Parkinson's disease (PD.Eight healthy subjects and 11 patients with mild to moderate PD had to judge, without vision, the curvature of a virtual "box" created by a robotic manipulandum. Their hands were either moved passively along a defined curved path or they actively explored the curved curvature of a virtual wall. The curvature was either concave or convex (bulging to the left or right and was judged in two locations of the hand workspace--a left workspace location, where the curved hand path was associated with curved shoulder and elbow joint paths, and a right workspace location in which these joint paths were nearly linear. After exploring the curvature of the virtual object, subjects had to judge whether the curvature was concave or convex. Based on these data, thresholds for curvature sensitivity were established. The main findings of the study are: First, 9 out 11 PD patients (82% showed elevated thresholds for detecting convex curvatures in at least one test condition. The respective median threshold for the PD group was increased by 343% when compared to the control group. Second, when distal hand paths became less associated with proximal joint paths (right workspace, haptic acuity was reduced substantially in both groups. Third, sensitivity to hand trajectory curvature was not improved during active exploration in either group.Our data demonstrate that PD is associated with a decreased acuity of the haptic sense, which may occur already at an early stage of the disease.

  10. FBAR syndapin 1 recognizes and stabilizes highly curved tubular membranes in a concentration dependent manner

    DEFF Research Database (Denmark)

    Ramesh, Pradeep; Baroji, Younes F.; Seyyed Reihani, Seyyed Nader

    2013-01-01

    Syndapin 1 FBAR, a member of the Bin-amphiphysin-Rvs (BAR) domain protein family, is known to induce membrane curvature and is an essential component in biological processes like endocytosis and formation and growth of neurites. We quantify the curvature sensing of FBAR on reconstituted porcine b...

  11. Magnetic vortices in nanocaps induced by curvature

    Science.gov (United States)

    Abdelgawad, Ahmed M.; Nambiar, Nikhil; Bapna, Mukund; Chen, Hao; Majetich, Sara A.

    2018-05-01

    Magnetic nanoparticles with room temperature remanent magnetic vortices stabilized by their curvature are very intriguing due to their potential use in biomedicine. In the present study, we investigate room temperature magnetic chirality in 100 nm diameter permalloy spherical caps with 10 nm and 30 nm thicknesses. Micromagnetic OOMMF simulations predict the equilibrium spin structure for these caps to form a vortex state. We fabricate the permalloy caps by sputtering permalloy on both close-packed and sparse arrays of polystyrene nanoparticles. Magnetic force microscopy scans show a clear signature of a vortex state in close-packed caps of both 10 nm and 30 nm thicknesses. Alternating gradient magnetometry measurements of the caps are consistent with a remnant vortex state in 30 nm thick caps and a transition to an onion state followed by a vortex state in 10 nm thick caps. Out-of-plane measurements supported by micromagnetic simulations shows that an out-of-plane field can stabilize a vortex state down to a diameter of 15 nm.

  12. Face recognition based on depth maps and surface curvature

    Science.gov (United States)

    Gordon, Gaile G.

    1991-09-01

    This paper explores the representation of the human face by features based on the curvature of the face surface. Curature captures many features necessary to accurately describe the face, such as the shape of the forehead, jawline, and cheeks, which are not easily detected from standard intensity images. Moreover, the value of curvature at a point on the surface is also viewpoint invariant. Until recently range data of high enough resolution and accuracy to perform useful curvature calculations on the scale of the human face had been unavailable. Although several researchers have worked on the problem of interpreting range data from curved (although usually highly geometrically structured) surfaces, the main approaches have centered on segmentation by signs of mean and Gaussian curvature which have not proved sufficient in themselves for the case of the human face. This paper details the calculation of principal curvature for a particular data set, the calculation of general surface descriptors based on curvature, and the calculation of face specific descriptors based both on curvature features and a priori knowledge about the structure of the face. These face specific descriptors can be incorporated into many different recognition strategies. A system that implements one such strategy, depth template comparison, giving recognition rates between 80% and 90% is described.

  13. Dynamic curvature sensing employing ionic-polymer–metal composite sensors

    International Nuclear Information System (INIS)

    Bahramzadeh, Yousef; Shahinpoor, Mohsen

    2011-01-01

    A dynamic curvature sensor is presented based on ionic-polymer–metal composite (IPMC) for curvature monitoring of deployable/inflatable dynamic space structures. Monitoring the curvature variation is of high importance in various engineering structures including shape monitoring of deployable/inflatable space structures in which the structural boundaries undergo a dynamic deployment process. The high sensitivity of IPMCs to the applied deformations as well as its flexibility make IPMCs a promising candidate for sensing of dynamic curvature changes. Herein, we explore the dynamic response of an IPMC sensor strip with respect to controlled curvature deformations subjected to different forms of input functions. Using a specially designed experimental setup, the voltage recovery effect, phase delay, and rate dependency of the output voltage signal of an IPMC curvature sensor are analyzed. Experimental results show that the IPMC sensor maintains the linearity, sensitivity, and repeatability required for curvature sensing. Besides, in order to describe the dynamic phenomena such as the rate dependency of the IPMC sensor, a chemo-electro-mechanical model based on the Poisson–Nernst–Planck (PNP) equation for the kinetics of ion diffusion is presented. By solving the governing partial differential equations the frequency response of the IPMC sensor is derived. The physical model is able to describe the dynamic properties of the IPMC sensor and the dependency of the signal on rate of excitations

  14. Peripheral Protein Unfolding Drives Membrane Bending.

    Science.gov (United States)

    Siaw, Hew Ming Helen; Raghunath, Gokul; Dyer, R Brian

    2018-06-20

    Dynamic modulation of lipid membrane curvature can be achieved by a number of peripheral protein binding mechanisms such as hy-drophobic insertion of amphipathic helices and membrane scaffolding. Recently, an alternative mechanism was proposed in which crowding of peripherally bound proteins induces membrane curvature through steric pressure generated by lateral collisions. This effect was enhanced using intrinsically disordered proteins that possess high hydrodynamic radii, prompting us to explore whether membrane bending can be triggered by the folding-unfolding transition of surface-bound proteins. We utilized histidine-tagged human serum albumin bound to Ni-NTA-DGS containing liposomes as our model system to test this hypothesis. We found that reduction of the disulfide bonds in the protein resulted in unfolding of HSA, which subsequently led to membrane tubule formation. The frequency of tubule formation was found to be significantly higher when the proteins were unfolded while being localized to a phase-separated domain as opposed to randomly distributed in fluid phase liposomes, indicating that the steric pressure generated from protein unfolding is directly responsible for membrane deformation. Our results are critical for the design of peripheral membrane protein-immobilization strategies and open new avenues for exploring mechanisms of membrane bending driven by conformational changes of peripheral membrane proteins.

  15. Interaction of Defensins with Model Cell Membranes

    Science.gov (United States)

    Sanders, Lori K.; Schmidt, Nathan W.; Yang, Lihua; Mishra, Abhijit; Gordon, Vernita D.; Selsted, Michael E.; Wong, Gerard C. L.

    2009-03-01

    Antimicrobial peptides (AMPs) comprise a key component of innate immunity for a wide range of multicellular organisms. For many AMPs, activity comes from their ability to selectively disrupt and lyse bacterial cell membranes. There are a number of proposed models for this action, but the detailed molecular mechanism of selective membrane permeation remains unclear. Theta defensins are circularized peptides with a high degree of selectivity. We investigate the interaction of model bacterial and eukaryotic cell membranes with theta defensins RTD-1, BTD-7, and compare them to protegrin PG-1, a prototypical AMP, using synchrotron small angle x-ray scattering (SAXS). The relationship between membrane composition and peptide induced changes in membrane curvature and topology is examined. By comparing the membrane phase behavior induced by these different peptides we will discuss the importance of amino acid composition and placement on membrane rearrangement.

  16. Profile Curvature Derivative Surface used to characterize the complexity of the seafloor around St. John, USVI

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Profile curvature was calculated from the bathymetry surface for each raster cell using the ArcGIS 3D Analyst "Curvature" Tool. Profile curvature describes the rate...

  17. Curvature Derivative Surface used to characterize the complexity of the seafloor around St. John, USVI

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Curvature was calculated from the bathymetry surface for each raster cell using the ArcGIS 3D Analyst "Curvature" Tool. Curvature describes the rate of change of...

  18. Influence of Coanda surface curvature on performance of bladeless fan

    Science.gov (United States)

    Li, Guoqi; Hu, Yongjun; Jin, Yingzi; Setoguchi, Toshiaki; Kim, Heuy Dong

    2014-10-01

    The unique Coanda surface has a great influence on the performance of bladeless fan. However, there is few studies to explain the relationship between the performance and Coanda surface curvature at present. In order to gain a qualitative understanding of effect of the curvature on the performance of bladeless fan, numerical studies are performed in this paper. Firstly, three-dimensional numerical simulation is done by Fluent software. For the purpose to obtain detailed information of the flow field around the Coanda surface, two-dimensional numerical simulation is also conducted. Five types of Coanda surfaces with different curvature are designed, and the flow behaviour and the performance of them are analyzed and compared with those of the prototype. The analysis indicates that the curvature of Coanda surface is strongly related to blowing performance, It is found that there is an optimal curvature of Coanda surfaces among the studied models. Simulation result shows that there is a special low pressure region. With increasing curvature in Y direction, several low pressure regions gradually enlarged, then begin to merge slowly, and finally form a large area of low pressure. From the analyses of streamlines and velocity angle, it is found that the magnitude of the curvature affects the flow direction and reasonable curvature can induce fluid flow close to the wall. Thus, it leads to that the curvature of the streamlines is consistent with that of Coanda surface. Meanwhile, it also causes the fluid movement towards the most suitable direction. This study will provide useful information to performance improvements of bladeless fans.

  19. Positive spatial curvature does not falsify the landscape

    Science.gov (United States)

    Horn, B.

    2017-12-01

    We present a simple cosmological model where the quantum tunneling of a scalar field rearranges the energetics of the matter sector, sending a stable static ancestor vacuum with positive spatial curvature into an inating solution with positive curvature. This serves as a proof of principle that an observation of positive spatial curvature does not falsify the hypothesis that our current observer patch originated from false vacuum tunneling in a string or field theoretic landscape. This poster submission is a summary of the work, and was presented at the 3rd annual ICPPA held in Moscow from October 2 to 5, 2017, by Prof. Rostislav Konoplich on behalf of the author.

  20. Curvature perturbation and waterfall dynamics in hybrid inflation

    International Nuclear Information System (INIS)

    Abolhasani, Ali Akbar; Firouzjahi, Hassan; Sasaki, Misao

    2011-01-01

    We investigate the parameter spaces of hybrid inflation model with special attention paid to the dynamics of waterfall field and curvature perturbations induced from its quantum fluctuations. Depending on the inflaton field value at the time of phase transition and the sharpness of the phase transition inflation can have multiple extended stages. We find that for models with mild phase transition the induced curvature perturbation from the waterfall field is too large to satisfy the COBE normalization. We investigate the model parameter space where the curvature perturbations from the waterfall quantum fluctuations vary between the results of standard hybrid inflation and the results obtained here

  1. Curvature perturbation and waterfall dynamics in hybrid inflation

    Energy Technology Data Exchange (ETDEWEB)

    Abolhasani, Ali Akbar [Department of Physics, Sharif University of Technology, Tehran (Iran, Islamic Republic of); Firouzjahi, Hassan [School of Physics, Institute for Research in Fundamental Sciences (IPM), P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of); Sasaki, Misao, E-mail: abolhasani@mail.ipm.ir, E-mail: firouz@mail.ipm.ir, E-mail: misao@yukawa.kyoto-u.ac.jp [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan)

    2011-10-01

    We investigate the parameter spaces of hybrid inflation model with special attention paid to the dynamics of waterfall field and curvature perturbations induced from its quantum fluctuations. Depending on the inflaton field value at the time of phase transition and the sharpness of the phase transition inflation can have multiple extended stages. We find that for models with mild phase transition the induced curvature perturbation from the waterfall field is too large to satisfy the COBE normalization. We investigate the model parameter space where the curvature perturbations from the waterfall quantum fluctuations vary between the results of standard hybrid inflation and the results obtained here.

  2. Geometry-specific scaling of detonation parameters from front curvature

    International Nuclear Information System (INIS)

    Jackson, Scott I.; Short, Mark

    2011-01-01

    It has previously been asserted that classical detonation curvature theory predicts that the critical diameter and the diameter-effect curve of a cylindrical high-explosive charge should scale with twice the thickness of an analogous two-dimensional explosive slab. The varied agreement of experimental results with this expectation have led some to question the ability of curvature-based concepts to predict detonation propagation in non-ideal explosives. This study addresses such claims by showing that the expected scaling relationship (hereafter referred to d = 2w) is not consistent with curvature-based Detonation Shock Dynamics (DSD) theory.

  3. Numerical studies of transverse curvature effects on transonic flow stability

    Science.gov (United States)

    Macaraeg, M. G.; Daudpota, Q. I.

    1992-01-01

    A numerical study of transverse curvature effects on compressible flow temporal stability for transonic to low supersonic Mach numbers is presented for axisymmetric modes. The mean flows studied include a similar boundary-layer profile and a nonsimilar axisymmetric boundary-layer solution. The effect of neglecting curvature in the mean flow produces only small quantitative changes in the disturbance growth rate. For transonic Mach numbers (1-1.4) and aerodynamically relevant Reynolds numbers (5000-10,000 based on displacement thickness), the maximum growth rate is found to increase with curvature - the maximum occurring at a nondimensional radius (based on displacement thickness) between 30 and 100.

  4. Public and private space curvature in Robertson-Walker universes.

    Science.gov (United States)

    Rindler, W.

    1981-05-01

    The question is asked: what space curvature would a fundamental observer in an ideal Robertson-Walker universe obtain by direct local spatial measurements, i.e., without reference to the motion pattern of the other galaxies? The answer is that he obtains the curvatureK of his “private” space generated by all the geodesics orthogonal to his world line at the moment in question, and that ˜K is related to the usual curvatureK=k/R 2 of the “public” space of galaxies byK=K+H 2/c2, whereH is Hubble's parameter.

  5. Higher Curvature Gravity from Entanglement in Conformal Field Theories

    Science.gov (United States)

    Haehl, Felix M.; Hijano, Eliot; Parrikar, Onkar; Rabideau, Charles

    2018-05-01

    By generalizing different recent works to the context of higher curvature gravity, we provide a unifying framework for three related results: (i) If an asymptotically anti-de Sitter (AdS) spacetime computes the entanglement entropies of ball-shaped regions in a conformal field theory using a generalized Ryu-Takayanagi formula up to second order in state deformations around the vacuum, then the spacetime satisfies the correct gravitational equations of motion up to second order around the AdS background. (ii) The holographic dual of entanglement entropy in higher curvature theories of gravity is given by the Wald entropy plus a particular correction term involving extrinsic curvatures. (iii) Conformal field theory relative entropy is dual to gravitational canonical energy (also in higher curvature theories of gravity). Especially for the second point, our novel derivation of this previously known statement does not involve the Euclidean replica trick.

  6. On the projective curvature tensor of generalized Sasakian-space ...

    African Journals Online (AJOL)

    space-forms under some conditions regarding projective curvature tensor. All the results obtained in this paper are in the form of necessary and sufficient conditions. Keywords: Generalized Sasakian-space-forms; projectively flat; ...

  7. Inverse curvature flows in asymptotically Robertson Walker spaces

    Science.gov (United States)

    Kröner, Heiko

    2018-04-01

    In this paper we consider inverse curvature flows in a Lorentzian manifold N which is the topological product of the real numbers with a closed Riemannian manifold and equipped with a Lorentzian metric having a future singularity so that N is asymptotically Robertson Walker. The flow speeds are future directed and given by 1 / F where F is a homogeneous degree one curvature function of class (K*) of the principal curvatures, i.e. the n-th root of the Gauss curvature. We prove longtime existence of these flows and that the flow hypersurfaces converge to smooth functions when they are rescaled with a proper factor which results from the asymptotics of the metric.

  8. On a class of graphs with prescribed mean curvature

    International Nuclear Information System (INIS)

    Duong Minh Duc; Costa Salavessa, I.M. de

    1989-11-01

    We study a class of quasilinear elliptic equations on the unit ball of R n and apply these results to get the existence of graphs with prescribed mean curvature on n-hyperbolic spaces. (author). 18 refs

  9. Higher-order curvature terms and extended inflation

    International Nuclear Information System (INIS)

    Wang Yun

    1990-01-01

    We consider higher-order curvature terms in context of the Brans-Dicke theory of gravity, and investigate the effects of these terms on extended inflationary theories. We find that the higher-order curvature terms tend to speed up inflation, although the original extended-inflation solutions are stable when these terms are small. Analytical solutions are found for two extreme cases: when the higher-order curvature terms are small, and when they dominate. A conformal transformation is employed in solving the latter case, and some of the subtleties in this technique are discussed. We note that percolation is less likely to occur when the higher-order curvature terms are present. An upper bound on α is expected if we are to avoid excessive and inadequate percolation of true-vacuum bubbles

  10. Gauge and non-gauge curvature tensor copies

    International Nuclear Information System (INIS)

    Srivastava, P.P.

    1982-10-01

    A procedure for constructing curvature tensor copies is discussed using the anholonomic geometrical framework. The corresponding geometries are compared and the notion of gauge copy is elucidated. An explicit calculation is also made. (author)

  11. Constant scalar curvature hypersurfaces in extended Schwarzschild space-time

    International Nuclear Information System (INIS)

    Pareja, M. J.; Frauendiener, J.

    2006-01-01

    We present a class of spherically symmetric hypersurfaces in the Kruskal extension of the Schwarzschild space-time. The hypersurfaces have constant negative scalar curvature, so they are hyperboloidal in the regions of space-time which are asymptotically flat

  12. Translating Solitons of Mean Curvature Flow of Noncompact Submanifolds

    International Nuclear Information System (INIS)

    Li Guanghan; Tian Daping; Wu Chuanxi

    2011-01-01

    We prove the existence and asymptotic behavior of rotationally symmetric solitons of mean curvature flow for noncompact submanifolds in Euclidean and Minkowski spaces, which generalizes part of the corresponding results for hypersurfaces of Jian.

  13. Curvature and elasticity of substitution: what is the link?

    Czech Academy of Sciences Publication Activity Database

    Matveenko, Andrei; Matveenko, V.

    2014-01-01

    Roč. 10, č. 2 (2014), s. 7-20 ISSN 1800-5845 Grant - others:UK(CZ) GAUK 308214 Institutional support: PRVOUK-P23 Keywords : curvature * elasticity of substitution * production function Subject RIV: AH - Economics

  14. Cosmic censorship, persistent curvature and asymptotic causal pathology

    International Nuclear Information System (INIS)

    Newman, R.P.A.C.

    1984-01-01

    The paper examines cosmic censorship in general relativity theory. Conformally flat space-times; persistent curvature; weakly asymptotically simple and empty asymptotes; censorship conditions; and the censorship theorem; are all discussed. (U.K.)

  15. No Large Scale Curvature Perturbations during Waterfall of Hybrid Inflation

    OpenAIRE

    Abolhasani, Ali Akbar; Firouzjahi, Hassan

    2010-01-01

    In this paper the possibility of generating large scale curvature perturbations induced from the entropic perturbations during the waterfall phase transition of standard hybrid inflation model is studied. We show that whether or not appreciable amounts of large scale curvature perturbations are produced during the waterfall phase transition depend crucially on the competition between the classical and the quantum mechanical back-reactions to terminate inflation. If one considers only the clas...

  16. Existence of conformal metrics on spheres with prescribed Paneitz curvature

    International Nuclear Information System (INIS)

    Ben Ayed, Mohamed; El Mehdi, Khalil

    2003-07-01

    In this paper we study the problem of prescribing a fourth order conformal invariant (the Paneitz curvature) on the n-spheres, with n ≥ 5. Using tools from the theory of critical points at infinity, we provide some topological conditions on the level sets of a given function defined on the sphere, under which we prove the existence of conformal metric with prescribed Paneitz curvature. (author)

  17. Inflation in a shear-or curvature-dominated universe

    International Nuclear Information System (INIS)

    Steigman, G.; Turner, M.S.

    1983-01-01

    We show that new inflation occurs even if the universe is shear-or (negative) curvature-dominated when the phase transition begins. In such situations the size of a causally coherent region, after inflation, is only slightly smaller (by powers, but not by exponential factors) than the usual result. The creation and evolution of density perturbations is unaffected. This result is marked contrast to 'old' inflation, where shear- or curvature-domination could quench inflation. (orig.)

  18. Curvature-driven acceleration: a utopia or a reality?

    International Nuclear Information System (INIS)

    Das, Sudipta; Banerjee, Narayan; Dadhich, Naresh

    2006-01-01

    The present work shows that a combination of nonlinear contributions from the Ricci curvature in Einstein field equations can drive a late time acceleration of expansion of the universe. The transit from the decelerated to the accelerated phase of expansion takes place smoothly without having to resort to a study of asymptotic behaviour. This result emphasizes the need for thorough and critical examination of models with nonlinear contribution from the curvature

  19. Curvature-driven acceleration: a utopia or a reality?

    Energy Technology Data Exchange (ETDEWEB)

    Das, Sudipta [Relativity and Cosmology Research Centre, Department of Physics, Jadavpur University, Calcutta-700 032 (India); Banerjee, Narayan [Relativity and Cosmology Research Centre, Department of Physics, Jadavpur University, Calcutta-700 032 (India); Dadhich, Naresh [Inter University Centre for Astronomy and Astrophysics, Post Bag 4, Ganeshkhind, Pune 411 007 (India)

    2006-06-21

    The present work shows that a combination of nonlinear contributions from the Ricci curvature in Einstein field equations can drive a late time acceleration of expansion of the universe. The transit from the decelerated to the accelerated phase of expansion takes place smoothly without having to resort to a study of asymptotic behaviour. This result emphasizes the need for thorough and critical examination of models with nonlinear contribution from the curvature.

  20. Existence of conformal metrics on spheres with prescribed Paneitz curvature

    CERN Document Server

    Ben-Ayed, M

    2003-01-01

    In this paper we study the problem of prescribing a fourth order conformal invariant (the Paneitz curvature) on the n-spheres, with n >= 5. Using tools from the theory of critical points at infinity, we provide some topological conditions on the level sets of a given function defined on the sphere, under which we prove the existence of conformal metric with prescribed Paneitz curvature.

  1. Curvature effects in carbon nanomaterials: Exohedral versus endohedral supercapacitors

    OpenAIRE

    Huang, Jingsong; Bobby,; Sumpter, Bobby G.; Meunier, Vincent; Yushin, Gleb; Portet, Cristelle; Gogotsi, Yury

    2010-01-01

    Capacitive energy storage mechanisms in nanoporous carbon supercapacitors hinge on endohedral interactions in carbon materials with macro-, meso-, and micropores that have negative surface curvature. In this article, we show that because of the positive curvature found in zero-dimensional carbon onions or one-dimensional carbon nanotube arrays, exohedral interactions cause the normalized capacitance to increase with decreasing particle size or tube diameter, in sharp contrast to the behavior ...

  2. Atomic fine structure in a space of constant curvature

    International Nuclear Information System (INIS)

    Bessis, N.; Bessis, G.; Shamseddine, R.

    1982-01-01

    As a contribution to a tentative formulation of atomic physics in a curved space, the determination of atomic fine structure energies in a space of constant curvature is investigated. Starting from the Dirac equation in a curved space-time, the analogue of the Pauli equation in a general coordinate system is derived. The theoretical curvature induced shifts and splittings of the fine structure energy levels are put in evidence and examined for the particular case of the hydrogenic n=2 levels. (author)

  3. On $L_p$ Affine Surface Area and Curvature Measures

    OpenAIRE

    Zhao, Yiming

    2015-01-01

    The relationship between $L_p$ affine surface area and curvature measures is investigated. As a result, a new representation of the existing notion of $L_p$ affine surface area depending only on curvature measures is derived. Direct proofs of the equivalence between this new representation and those previously known are provided. The proofs show that the new representation is, in a sense, "polar" to that of Lutwak's and "dual" to that of Sch\\"utt & Werner's.

  4. Curvature reduces bending strains in the quokka femur

    Directory of Open Access Journals (Sweden)

    Kyle McCabe

    2017-03-01

    Full Text Available This study explores how curvature in the quokka femur may help to reduce bending strain during locomotion. The quokka is a small wallaby, but the curvature of the femur and the muscles active during stance phase are similar to most quadrupedal mammals. Our hypothesis is that the action of hip extensor and ankle plantarflexor muscles during stance phase place cranial bending strains that act to reduce the caudal curvature of the femur. Knee extensors and biarticular muscles that span the femur longitudinally create caudal bending strains in the caudally curved (concave caudal side bone. These opposing strains can balance each other and result in less strain on the bone. We test this idea by comparing the performance of a normally curved finite element model of the quokka femur to a digitally straightened version of the same bone. The normally curved model is indeed less strained than the straightened version. To further examine the relationship between curvature and the strains in the femoral models, we also tested an extra-curved and a reverse-curved version with the same loads. There appears to be a linear relationship between the curvature and the strains experienced by the models. These results demonstrate that longitudinal curvature in bones may be a manipulable mechanism whereby bone can induce a strain gradient to oppose strains induced by habitual loading.

  5. RodZ promotes MreB polymer formation and curvature localization to determine the cylindrical uniformity of E. coli shape

    OpenAIRE

    Bratton, Benjamin; Morgenstein, Randy; Shaevitz, Joshua; Gitai, Zemer

    2017-01-01

    Cell shape in bacteria is determined by the cell wall, which is synthesized by a variety of proteins whose actions are coordinated by the actin-like MreB protein. MreB uses local geometric cues of envelope curvature to avoid the cell poles and localize to specific regions of the cell body. However, it remains unclear whether MreB's curvature preference is regulated by additional factors, and which features of MreB are essential for specific aspects of rod shape growth, such as cylindrical uni...

  6. Effective tension and fluctuations in active membranes

    OpenAIRE

    Loubet, Bastien; Seifert, Udo; Lomholt, Michael Andersen

    2011-01-01

    We calculate the fluctuation spectrum of the shape of a lipid vesicle or cell exposed to a nonthermal source of noise. In particular we take into account constraints on the membrane area and the volume of fluid that it encapsulates when obtaining expressions for the dependency of the membrane tension on the noise. We then investigate three possible origins of the non-thermal noise taken from the literature: A direct force, which models an external medium pushing on the membrane. A curvature f...

  7. Spinal curvature and characteristics of postural change in pregnant women.

    Science.gov (United States)

    Okanishi, Natsuko; Kito, Nobuhiro; Akiyama, Mitoshi; Yamamoto, Masako

    2012-07-01

    Pregnant women often report complaints due to physiological and postural changes. Postural changes during pregnancy may cause low back pain and pelvic girdle pain. This study aimed to compare the characteristics of postural changes in pregnant compared with non-pregnant women. Prospective case-control study. Pregnancy care center. Fifteen women at 17-34 weeks pregnancy comprised the study group, while 10 non-pregnant female volunteers comprised the control group. Standing posture was evaluated in the sagittal plane with static digital pictures. Two angles were measured by image analysis software: (1) between the trunk and pelvis; and (2) between the trunk and lower extremity. Spinal curvature was measured with Spinal Mouse® to calculate the means of sacral inclination, thoracic and lumbar curvature and inclination. The principal components were calculated until eigenvalues surpassed 1. Three distinct factors with eigenvalues of 1.00-2.49 were identified, consistent with lumbosacral spinal curvature and inclination, thoracic spine curvature, and inclination of the body. These factors accounted for 77.2% of the total variance in posture variables. Eleven pregnant women showed postural characteristics of lumbar kyphosis and sacral posterior inclination. Body inclination showed a variety of patterns compared with those in healthy women. Spinal curvature demonstrated a tendency for lumbar kyphosis in pregnant women. Pregnancy may cause changes in spinal curvature and posture, which may in turn lead to relevant symptoms. Our data provide a basis for investigating the effects of spinal curvature and postural changes on symptoms during pregnancy. © 2012 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2012 Nordic Federation of Societies of Obstetrics and Gynecology.

  8. Sequence periodicity in nucleosomal DNA and intrinsic curvature.

    Science.gov (United States)

    Nair, T Murlidharan

    2010-05-17

    Most eukaryotic DNA contained in the nucleus is packaged by wrapping DNA around histone octamers. Histones are ubiquitous and bind most regions of chromosomal DNA. In order to achieve smooth wrapping of the DNA around the histone octamer, the DNA duplex should be able to deform and should possess intrinsic curvature. The deformability of DNA is a result of the non-parallelness of base pair stacks. The stacking interaction between base pairs is sequence dependent. The higher the stacking energy the more rigid the DNA helix, thus it is natural to expect that sequences that are involved in wrapping around the histone octamer should be unstacked and possess intrinsic curvature. Intrinsic curvature has been shown to be dictated by the periodic recurrence of certain dinucleotides. Several genome-wide studies directed towards mapping of nucleosome positions have revealed periodicity associated with certain stretches of sequences. In the current study, these sequences have been analyzed with a view to understand their sequence-dependent structures. Higher order DNA structures and the distribution of molecular bend loci associated with 146 base nucleosome core DNA sequence from C. elegans and chicken have been analyzed using the theoretical model for DNA curvature. The curvature dispersion calculated by cyclically permuting the sequences revealed that the molecular bend loci were delocalized throughout the nucleosome core region and had varying degrees of intrinsic curvature. The higher order structures associated with nucleosomes of C.elegans and chicken calculated from the sequences revealed heterogeneity with respect to the deviation of the DNA axis. The results points to the possibility of context dependent curvature of varying degrees to be associated with nucleosomal DNA.

  9. Fuel cell membrane humidification

    Science.gov (United States)

    Wilson, Mahlon S.

    1999-01-01

    A polymer electrolyte membrane fuel cell assembly has an anode side and a cathode side separated by the membrane and generating electrical current by electrochemical reactions between a fuel gas and an oxidant. The anode side comprises a hydrophobic gas diffusion backing contacting one side of the membrane and having hydrophilic areas therein for providing liquid water directly to the one side of the membrane through the hydrophilic areas of the gas diffusion backing. In a preferred embodiment, the hydrophilic areas of the gas diffusion backing are formed by sewing a hydrophilic thread through the backing. Liquid water is distributed over the gas diffusion backing in distribution channels that are separate from the fuel distribution channels.

  10. Anionic lipids and the maintenance of membrane electrostatics in eukaryotes.

    Science.gov (United States)

    Platre, Matthieu Pierre; Jaillais, Yvon

    2017-02-01

    A wide range of signaling processes occurs at the cell surface through the reversible association of proteins from the cytosol to the plasma membrane. Some low abundant lipids are enriched at the membrane of specific compartments and thereby contribute to the identity of cell organelles by acting as biochemical landmarks. Lipids also influence membrane biophysical properties, which emerge as an important feature in specifying cellular territories. Such parameters are crucial for signal transduction and include lipid packing, membrane curvature and electrostatics. In particular, membrane electrostatics specifies the identity of the plasma membrane inner leaflet. Membrane surface charges are carried by anionic phospholipids, however the exact nature of the lipid(s) that powers the plasma membrane electrostatic field varies among eukaryotes and has been hotly debated during the last decade. Herein, we discuss the role of anionic lipids in setting up plasma membrane electrostatics and we compare similarities and differences that were found in different eukaryotic cells.

  11. The speed-curvature power law of movements: a reappraisal.

    Science.gov (United States)

    Zago, Myrka; Matic, Adam; Flash, Tamar; Gomez-Marin, Alex; Lacquaniti, Francesco

    2018-01-01

    Several types of curvilinear movements obey approximately the so called 2/3 power law, according to which the angular speed varies proportionally to the 2/3 power of the curvature. The origin of the law is debated but it is generally thought to depend on physiological mechanisms. However, a recent paper (Marken and Shaffer, Exp Brain Res 88:685-690, 2017) claims that this power law is simply a statistical artifact, being a mathematical consequence of the way speed and curvature are calculated. Here we reject this hypothesis by showing that the speed-curvature power law of biological movements is non-trivial. First, we confirm that the power exponent varies with the shape of human drawing movements and with environmental factors. Second, we report experimental data from Drosophila larvae demonstrating that the power law does not depend on how curvature is calculated. Third, we prove that the law can be violated by means of several mathematical and physical examples. Finally, we discuss biological constraints that may underlie speed-curvature power laws discovered in empirical studies.

  12. Non-linear temperature-dependent curvature of a phase change composite bimorph beam

    Science.gov (United States)

    Blonder, Greg

    2017-06-01

    Bimorph films curl in response to temperature. The degree of curvature typically varies in proportion to the difference in thermal expansion of the individual layers, and linearly with temperature. In many applications, such as controlling a thermostat, this gentle linear behavior is acceptable. In other cases, such as opening or closing a valve or latching a deployable column into place, an abrupt motion at a fixed temperature is preferred. To achieve this non-linear motion, we describe the fabrication and performance of a new bilayer structure we call a ‘phase change composite bimorph (PCBM)’. In a PCBM, one layer in the bimorph is a composite containing small inclusions of phase change materials. When the inclusions melt, their large (generally positive and  >1%) expansion coefficient induces a strong, reversible step function jump in bimorph curvature. The measured jump amplitude and thermal response is consistent with theory, and can be harnessed by a new class of actuators and sensors.

  13. Curvature-induced electron localization in developable Moebius-like nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Korte, A P; Van der Heijden, G H M, E-mail: a.korte@ucl.ac.u, E-mail: g.heijden@ucl.ac.u [Centre for Nonlinear Dynamics, University College London, Chadwick Building, Gower Street, London WC1E 6BT (United Kingdom)

    2009-12-02

    We study curvature effects and localization of non-interacting electrons confined to developable one-sided elastic sheets motivated by recent nanostructured origami techniques for creating and folding extremely thin membrane structures. The most famous one-sided sheet is the Moebius strip but the theory we develop allows for arbitrary linking number. Unlike previous work in the literature we do not assume a shape for the elastic structures. Rather, we find the shape by minimizing the elastic energy, i.e., solving the Euler-Lagrange equations for the bending energy functional. This shape varies with the aspect ratio of the sheet and affects the potential experienced by the particles. Depending on the link there is a number of singular points on the edge of the structure where the bending energy density goes to infinity, leading to deep potential wells. The inverse participation ratio is used to show that electrons are increasingly localized to the higher-curvature regions of the higher-width structures, where sharp creases radiating out from the singular points could form channels for particle transport. Our geometric formulation could be used to study transport properties of Moebius strips and other components in nanoscale devices.

  14. Curvature-induced electron localization in developable Moebius-like nanostructures

    International Nuclear Information System (INIS)

    Korte, A P; Van der Heijden, G H M

    2009-01-01

    We study curvature effects and localization of non-interacting electrons confined to developable one-sided elastic sheets motivated by recent nanostructured origami techniques for creating and folding extremely thin membrane structures. The most famous one-sided sheet is the Moebius strip but the theory we develop allows for arbitrary linking number. Unlike previous work in the literature we do not assume a shape for the elastic structures. Rather, we find the shape by minimizing the elastic energy, i.e., solving the Euler-Lagrange equations for the bending energy functional. This shape varies with the aspect ratio of the sheet and affects the potential experienced by the particles. Depending on the link there is a number of singular points on the edge of the structure where the bending energy density goes to infinity, leading to deep potential wells. The inverse participation ratio is used to show that electrons are increasingly localized to the higher-curvature regions of the higher-width structures, where sharp creases radiating out from the singular points could form channels for particle transport. Our geometric formulation could be used to study transport properties of Moebius strips and other components in nanoscale devices.

  15. Waterfall field in hybrid inflation and curvature perturbation

    International Nuclear Information System (INIS)

    Gong, Jinn-Ouk; Sasaki, Misao

    2011-01-01

    We study carefully the contribution of the waterfall field to the curvature perturbation at the end of hybrid inflation. In particular we clarify the parameter dependence analytically under reasonable assumptions on the model parameters. After calculating the mode function of the waterfall field, we use the δN formalism and confirm the previously obtained result that the power spectrum is very blue with the index 4 and is absolutely negligible on large scales. However, we also find that the resulting curvature perturbation is highly non-Gaussian and hence we calculate the bispectrum. We find that the bispectrum is at leading order independent of momentum and exhibits its peak at the equilateral limit, though it is unobservably small on large scales. We also present the one-point probability distribution function of the curvature perturbation

  16. Waterfall field in hybrid inflation and curvature perturbation

    Energy Technology Data Exchange (ETDEWEB)

    Gong, Jinn-Ouk [Instituut-Lorentz for Theoretical Physics, Universiteit Leiden, 2333 CA Leiden (Netherlands); Sasaki, Misao, E-mail: jgong@lorentz.leidenuniv.nl, E-mail: misao@yukawa.kyoto-u.ac.jp [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan)

    2011-03-01

    We study carefully the contribution of the waterfall field to the curvature perturbation at the end of hybrid inflation. In particular we clarify the parameter dependence analytically under reasonable assumptions on the model parameters. After calculating the mode function of the waterfall field, we use the δN formalism and confirm the previously obtained result that the power spectrum is very blue with the index 4 and is absolutely negligible on large scales. However, we also find that the resulting curvature perturbation is highly non-Gaussian and hence we calculate the bispectrum. We find that the bispectrum is at leading order independent of momentum and exhibits its peak at the equilateral limit, though it is unobservably small on large scales. We also present the one-point probability distribution function of the curvature perturbation.

  17. Evolution of curvature perturbation in generalized gravity theories

    International Nuclear Information System (INIS)

    Matsuda, Tomohiro

    2009-01-01

    Using the cosmological perturbation theory in terms of the δN formalism, we find the simple formulation of the evolution of the curvature perturbation in generalized gravity theories. Compared with the standard gravity theory, a crucial difference appears in the end-boundary of the inflationary stage, which is due to the non-ideal form of the energy-momentum tensor that depends explicitly on the curvature scalar. Recent study shows that ultraviolet-complete quantum theory of gravity (Horava-Lifshitz gravity) can be approximated by using a generalized gravity action. Our paper may give an important step in understanding the evolution of the curvature perturbation during inflation, where the energy-momentum tensor may not be given by the ideal form due to the corrections from the fundamental theory.

  18. On the scalar curvature of self-dual manifolds

    International Nuclear Information System (INIS)

    Kim, J.

    1992-08-01

    We generalize LeBrun's explicit ''hyperbolic ansatz'' construction of self-dual metrics on connected sums of conformally flat manifolds and CP 2 's through a systematic use of the theory of hyperbolic geometry and Kleinian groups. (This construction produces, for example, all self-dual manifolds with semi-free S 1 -action and with either nonnegative scalar curvature or positive-definite intersection form.) We then point out a simple criterion for determining the sign of the scalar curvature of these conformal metrics. Exploiting this, we then show that the sign of the scalar curvature can change on connected components of the moduli space of self-dual metrics, thereby answering a question raised by King and Kotschick. (author). Refs

  19. Vibration Analysis of Circular Arch Element Using Curvature

    Directory of Open Access Journals (Sweden)

    H. Saffari

    2008-01-01

    Full Text Available In this paper, a finite element technique was used to determine the natural frequencies, and the mode shapes of a circular arch element was based on the curvature, which can fully represent the bending energy and by the equilibrium equations, the shear and axial strain energy were incorporated into the formulation. The treatment of general boundary conditions dose need a consideration when the element is incorporated by the curvature-based formula. This can be obtained by the introduction of a transformation matrix between nodal curvatures and nodal displacements. The equation of the motion for the element was obtained by the Lagrangian equation. Four examples are presented in order to verify the element formulation and its analytical capability.

  20. Linearized curvatures for auxiliary fields in the de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Vasiliev, M A

    1988-09-19

    New consistent linearized curvatures in the de Sitter space are constructed. The sequence of actions, describing bosonic and fermionic gauge auxiliary fields, is found based on these curvatures. The proposed actions are parametrized by two integer parameters, n greater than or equal to 0 and m greater than or equal to 0. The simplest case n=m=0 corresponds in the flat limit to the auxiliary fields of 'new minimal' supergravity. The hamiltonian formulation is developed for the auxiliary fields suggested; hamiltonians and first- and second-class constraints are constructed. Using these results, it is shown that the systems of fields proposed possess no dynamical degrees of freedom in de Sitter and flat spaces. In addition the hamiltonian formalism is analysed for some free dynamical systems based on linearized higher-spin curvatures introduced previously.

  1. Local divergence and curvature divergence in first order optics

    Science.gov (United States)

    Mafusire, Cosmas; Krüger, Tjaart P. J.

    2018-06-01

    The far-field divergence of a light beam propagating through a first order optical system is presented as a square root of the sum of the squares of the local divergence and the curvature divergence. The local divergence is defined as the ratio of the beam parameter product to the beam width whilst the curvature divergence is a ratio of the space-angular moment also to the beam width. It is established that the beam’s focusing parameter can be defined as a ratio of the local divergence to the curvature divergence. The relationships between the two divergences and other second moment-based beam parameters are presented. Their various mathematical properties are presented such as their evolution through first order systems. The efficacy of the model in the analysis of high power continuous wave laser-based welding systems is briefly discussed.

  2. Quantum charged rigid membrane

    Energy Technology Data Exchange (ETDEWEB)

    Cordero, Ruben [Departamento de Fisica, Escuela Superior de Fisica y Matematicas del I.P.N., Unidad Adolfo Lopez Mateos, Edificio 9, 07738 Mexico, D.F. (Mexico); Molgado, Alberto [Unidad Academica de Fisica, Universidad Autonoma de Zacatecas, Zacatecas Zac. (Mexico); Rojas, Efrain, E-mail: cordero@esfm.ipn.mx, E-mail: amolgado@fisica.uaz.edu.mx, E-mail: efrojas@uv.mx [Departamento de Fisica, Facultad de Fisica e Inteligencia Artificial, Universidad Veracruzana, 91000 Xalapa, Veracruz (Mexico)

    2011-03-21

    The early Dirac proposal to model the electron as a charged membrane is reviewed. A rigidity term, instead of the natural membrane tension, involving linearly the extrinsic curvature of the worldvolume swept out by the membrane is considered in the action modeling the bubble in the presence of an electromagnetic field. We set up this model as a genuine second-order derivative theory by considering a non-trivial boundary term which plays a relevant part in our formulation. The Lagrangian in question is linear in the bubble acceleration and by means of the Ostrogradski-Hamiltonian approach, we observed that the theory comprises the management of both first- and second-class constraints. We thus show that our second-order approach is robust allowing for a proper quantization. We found an effective quantum potential which permits us to compute bounded states for the system. We comment on the possibility of describing brane world universes by invoking this kind of second-order correction terms.

  3. Quantum charged rigid membrane

    International Nuclear Information System (INIS)

    Cordero, Ruben; Molgado, Alberto; Rojas, Efrain

    2011-01-01

    The early Dirac proposal to model the electron as a charged membrane is reviewed. A rigidity term, instead of the natural membrane tension, involving linearly the extrinsic curvature of the worldvolume swept out by the membrane is considered in the action modeling the bubble in the presence of an electromagnetic field. We set up this model as a genuine second-order derivative theory by considering a non-trivial boundary term which plays a relevant part in our formulation. The Lagrangian in question is linear in the bubble acceleration and by means of the Ostrogradski-Hamiltonian approach, we observed that the theory comprises the management of both first- and second-class constraints. We thus show that our second-order approach is robust allowing for a proper quantization. We found an effective quantum potential which permits us to compute bounded states for the system. We comment on the possibility of describing brane world universes by invoking this kind of second-order correction terms.

  4. Membrane fusion

    DEFF Research Database (Denmark)

    Bendix, Pól Martin

    2015-01-01

    At Stanford University, Boxer lab, I worked on membrane fusion of small unilamellar lipid vesicles to flat membranes tethered to glass surfaces. This geometry closely resembles biological systems in which liposomes fuse to plasma membranes. The fusion mechanism was studied using DNA zippering...... between complementary strands linked to the two apposing membranes closely mimicking the zippering mechanism of SNARE fusion complexes....

  5. VIERS- User Preference Service

    Data.gov (United States)

    Department of Veterans Affairs — The Preferences service provides a means to store, retrieve, and manage user preferences. The service supports definition of enterprise wide preferences, as well as...

  6. Gas phase fractionation method using porous ceramic membrane

    Science.gov (United States)

    Peterson, Reid A.; Hill, Jr., Charles G.; Anderson, Marc A.

    1996-01-01

    Flaw-free porous ceramic membranes fabricated from metal sols and coated onto a porous support are advantageously used in gas phase fractionation methods. Mean pore diameters of less than 40 .ANG., preferably 5-20 .ANG. and most preferably about 15 .ANG., are permeable at lower pressures than existing membranes. Condensation of gases in small pores and non-Knudsen membrane transport mechanisms are employed to facilitate and increase membrane permeability and permselectivity.

  7. Some curvature properties of quarter symmetric metric connections

    International Nuclear Information System (INIS)

    Rastogi, S.C.

    1986-08-01

    A linear connection Γ ji h with torsion tensor T j h P i -T i h P j , where T j h is an arbitrary (1,1) tensor field and P i is a 1-form, has been called a quarter-symmetric connection by Golab. Some properties of such connections have been studied by Rastogi, Mishra and Pandey, and Yano and Imai. In this paper based on the curvature tensor of quarter-symmetric metric connection we define a tensor analogous to conformal curvature tensor and study some properties of such a tensor. (author)

  8. Vertex Normals and Face Curvatures of Triangle Meshes

    KAUST Repository

    Sun, Xiang

    2016-08-12

    This study contributes to the discrete differential geometry of triangle meshes, in combination with discrete line congruences associated with such meshes. In particular we discuss when a congruence defined by linear interpolation of vertex normals deserves to be called a ʼnormal’ congruence. Our main results are a discussion of various definitions of normality, a detailed study of the geometry of such congruences, and a concept of curvatures and shape operators associated with the faces of a triangle mesh. These curvatures are compatible with both normal congruences and the Steiner formula.

  9. Berry Curvature in Magnon-Phonon Hybrid Systems.

    Science.gov (United States)

    Takahashi, Ryuji; Nagaosa, Naoto

    2016-11-18

    We study theoretically the Berry curvature of the magnon induced by the hybridization with the acoustic phonons via the spin-orbit and dipolar interactions. We first discuss the magnon-phonon hybridization via the dipolar interaction, and show that the dispersions have gapless points in momentum space, some of which form a loop. Next, when both spin-orbit and dipolar interactions are considered, we show anisotropic texture of the Berry curvature and its divergence with and without gap closing. Realistic evaluation of the consequent anomalous velocity is given for yttrium iron garnet.

  10. Prescribed curvature tensor in locally conformally flat manifolds

    Science.gov (United States)

    Pina, Romildo; Pieterzack, Mauricio

    2018-01-01

    A global existence theorem for the prescribed curvature tensor problem in locally conformally flat manifolds is proved for a special class of tensors R. Necessary and sufficient conditions for the existence of a metric g ¯ , conformal to Euclidean g, are determined such that R ¯ = R, where R ¯ is the Riemannian curvature tensor of the metric g ¯ . The solution to this problem is given explicitly for special cases of the tensor R, including the case where the metric g ¯ is complete on Rn. Similar problems are considered for locally conformally flat manifolds.

  11. Deciphering the BAR code of membrane modulators.

    Science.gov (United States)

    Salzer, Ulrich; Kostan, Julius; Djinović-Carugo, Kristina

    2017-07-01

    The BAR domain is the eponymous domain of the "BAR-domain protein superfamily", a large and diverse set of mostly multi-domain proteins that play eminent roles at the membrane cytoskeleton interface. BAR domain homodimers are the functional units that peripherally associate with lipid membranes and are involved in membrane sculpting activities. Differences in their intrinsic curvatures and lipid-binding properties account for a large variety in membrane modulating properties. Membrane activities of BAR domains are further modified and regulated by intramolecular or inter-subunit domains, by intermolecular protein interactions, and by posttranslational modifications. Rather than providing detailed cell biological information on single members of this superfamily, this review focuses on biochemical, biophysical, and structural aspects and on recent findings that paradigmatically promote our understanding of processes driven and modulated by BAR domains.

  12. Complex Dynamic Development of Poliovirus Membranous Replication Complexes

    Science.gov (United States)

    Nair, Vinod; Hansen, Bryan T.; Hoyt, Forrest H.; Fischer, Elizabeth R.; Ehrenfeld, Ellie

    2012-01-01

    Replication of all positive-strand RNA viruses is intimately associated with membranes. Here we utilize electron tomography and other methods to investigate the remodeling of membranes in poliovirus-infected cells. We found that the viral replication structures previously described as “vesicles” are in fact convoluted, branching chambers with complex and dynamic morphology. They are likely to originate from cis-Golgi membranes and are represented during the early stages of infection by single-walled connecting and branching tubular compartments. These early viral organelles gradually transform into double-membrane structures by extension of membranous walls and/or collapsing of the luminal cavity of the single-membrane structures. As the double-membrane regions develop, they enclose cytoplasmic material. At this stage, a continuous membranous structure may have double- and single-walled membrane morphology at adjacent cross-sections. In the late stages of the replication cycle, the structures are represented mostly by double-membrane vesicles. Viral replication proteins, double-stranded RNA species, and actively replicating RNA are associated with both double- and single-membrane structures. However, the exponential phase of viral RNA synthesis occurs when single-membrane formations are predominant in the cell. It has been shown previously that replication complexes of some other positive-strand RNA viruses form on membrane invaginations, which result from negative membrane curvature. Our data show that the remodeling of cellular membranes in poliovirus-infected cells produces structures with positive curvature of membranes. Thus, it is likely that there is a fundamental divergence in the requirements for the supporting cellular membrane-shaping machinery among different groups of positive-strand RNA viruses. PMID:22072780

  13. Black hole production in particle collisions and higher curvature gravity

    International Nuclear Information System (INIS)

    Rychkov, Vyacheslav S.

    2004-01-01

    The problem of black hole production in trans-Planckian particle collisions is revisited, in the context of large extra dimensions scenarios of TeV-scale gravity. The validity of the standard description of this process (two colliding Aichelburg-Sexl shock waves in classical Einstein gravity) is questioned. It is observed that the classical spacetime has large curvature along the transverse collision plane, as signaled by the curvature invariant (R μνλσ ) 2 . Thus quantum gravity effects, and in particular higher curvature corrections to the Einstein gravity, cannot be ignored. To give a specific example of what may happen, the collision is reanalyzed in the Einstein-Lanczos-Lovelock gravity theory, which modifies the Einstein-Hilbert Lagrangian by adding a particular 'Gauss-Bonnet' combination of curvature squared terms. The analysis uses a series of approximations, which reduce the field equations to a tractable second order nonlinear PDE of the Monge-Ampere type. It is found that the resulting spacetime is significantly different from the pure Einstein case in the future of the transverse collision plane. These considerations cast serious doubts on the geometric cross section estimate, which is based on the classical Einstein gravity description of the black hole production process

  14. On conformal Paneitz curvature equations in higher dimensional spheres

    International Nuclear Information System (INIS)

    El Mehdi, Khalil

    2004-11-01

    We study the problem of prescribing the Paneitz curvature on higher dimensional spheres. Particular attention is paid to the blow-up points, i.e. the critical points at infinity of the corresponding variational problem. Using topological tools and a careful analysis of the gradient flow lines in the neighborhood of such critical points at infinity, we prove some existence results. (author)

  15. Continuous-Curvature Path Generation Using Fermat's Spiral

    Directory of Open Access Journals (Sweden)

    Anastasios M. Lekkas

    2013-10-01

    Full Text Available This paper proposes a novel methodology, based on Fermat's spiral (FS, for constructing curvature-continuous parametric paths in a plane. FS has a zero curvature at its origin, a property that allows it to be connected with a straight line smoothly, that is, without the curvature discontinuity which occurs at the transition point between a line and a circular arc when constructing Dubins paths. Furthermore, contrary to the computationally expensive clothoids, FS is described by very simple parametric equations that are trivial to compute. On the downside, computing the length of an FS arc involves a Gaussian hypergeometric function. However, this function is absolutely convergent and it is also shown that it poses no restrictions to the domain within which the length can be calculated. In addition, we present an alternative parametrization of FS which eliminates the parametric speed singularity at the origin, hence making the spiral suitable for path-tracking applications. A detailed description of how to construct curvature-continuous paths with FS is given.

  16. Eigenvalue estimates for submanifolds with bounded f-mean curvature

    Indian Academy of Sciences (India)

    GUANGYUE HUANG

    1College of Mathematics and Information Science, Henan Normal University,. Xinxiang 453007 ... submanifolds in a hyperbolic space with the norm of their mean curvature vector bounded above by a constant. ..... [2] Batista M, Cavalcante M P and Pyo J, Some isoperimetric inequalities and eigenvalue estimates in ...

  17. Multiple spinal curvatures in a captive African dwarf crocodile ...

    African Journals Online (AJOL)

    A 4 year old African dwarf crocodile that had been domiciled at the Zoological Gardens, University of Ibadan for 2 years was presented with a history of anorexia of two weeks' duration and reluctance to move for about a week prior to presentation. Physical examination revealed body curvatures and radiography was ...

  18. Intracellular magnetophoresis of amyloplasts and induction of root curvature

    Science.gov (United States)

    Kuznetsov, O. A.; Hasenstein, K. H.

    1996-01-01

    High-gradient magnetic fields (HGMFs) were used to induce intracellular magnetophoresis of amyloplasts. The HGMFs were generated by placing a small ferromagnetic wedge into a uniform magnetic field or at the gap edge between two permanent magnets. In the vicinity of the tip of the wedge the dynamic factor of the magnetic field, delta(H2/2), was about 10(9) Oe2.cm-1, which subjected the amyloplasts to a force comparable to that of gravity. When roots of 2-d-old seedlings of flax (Linum usitatissimum L.) were positioned vertically and exposed to an HGMF, curvature away from the wedge was transient and lasted approximately 1 h. Average curvature obtained after placing magnets, wedge and seedlings on a 1-rpm clinostat for 2 h was 33 +/- 5 degrees. Roots of horizontally placed control seedlings without rotation curved about 47 +/- 4 degrees. The time course of curvature and changes in growth rate were similar for gravicurvature and for root curvature induced by HGMFs. Microscopy showed displacement of amyloplasts in vitro and in vivo. Studies with Arabidopsis thaliana (L.) Heynh. showed that the wild type responded to HGMFs but the starchless mutant TC7 did not. The data indicate that a magnetic force can be used to study the gravisensing and response system of roots.

  19. Zero mean curvature surfaces of mixed type in Minkowski space

    International Nuclear Information System (INIS)

    Klyachin, V A

    2003-01-01

    We investigate zero mean curvature surfaces in the Minkowski space R 3 1 such that their first fundamental quadratic form changes signature. Part of such a surface is space-like and part is time-like. We obtain complete information about the structure of the set of points where the surface changes type and prove the related existence and uniqueness theorems

  20. On the Curvature and Heat Flow on Hamiltonian Systems

    Directory of Open Access Journals (Sweden)

    Ohta Shin-ichi

    2014-01-01

    Full Text Available We develop the differential geometric and geometric analytic studies of Hamiltonian systems. Key ingredients are the curvature operator, the weighted Laplacian, and the associated Riccati equation.We prove appropriate generalizations of the Bochner-Weitzenböck formula and Laplacian comparison theorem, and study the heat flow.

  1. The Paneitz curvature problem on lower dimensional spheres

    CERN Document Server

    Ben-Ayed, M

    2003-01-01

    In this paper we prescribe a fourth order conformal invariant (the Paneitz curvature) on the n-spheres, with n is an element of left brace 5, 6 right brace. Using dynamical and topological methods involving the study of critical points at infinity of the associated variational problem, we prove some existence results.

  2. Forelimb bone curvature in terrestrial and arboreal mammals

    Directory of Open Access Journals (Sweden)

    Keith Henderson

    2017-04-01

    Full Text Available It has recently been proposed that the caudal curvature (concave caudal side observed in the radioulna of terrestrial quadrupeds is an adaptation to the habitual action of the triceps muscle which causes cranial bending strains (compression on cranial side. The caudal curvature is proposed to be adaptive because longitudinal loading induces caudal bending strains (increased compression on the caudal side, and these opposing bending strains counteract each other leaving the radioulna less strained. If this is true for terrestrial quadrupeds, where triceps is required for habitual elbow extension, then we might expect that in arboreal species, where brachialis is habitually required to maintain elbow flexion, the radioulna should instead be cranially curved. This study measures sagittal curvature of the ulna in a range of terrestrial and arboreal primates and marsupials, and finds that their ulnae are curved in opposite directions in these two locomotor categories. This study also examines sagittal curvature in the humerus in the same species, and finds differences that can be attributed to similar adaptations: the bone is curved to counter the habitual muscle action required by the animal’s lifestyle, the difference being mainly in the distal part of the humerus, where arboreal animals tend have a cranial concavity, thought to be in response the carpal and digital muscles that pull cranially on the distal humerus.

  3. Axial Length/Corneal Radius of Curvature Ratio and Refractive ...

    African Journals Online (AJOL)

    2017-12-05

    Dec 5, 2017 ... variously described as determined by the ocular biometric variables. There have been many studies on the relationship between refractive error and ocular axial length (AL), anterior chamber depth, corneal radius of curvature (CR), keratometric readings as well as other ocular biometric variables such as ...

  4. GEOMETRY OF COMPLETE HYPERSURFACES EVOLVED BY MEAN CURVATURE FLOW

    Institute of Scientific and Technical Information of China (English)

    盛为民

    2003-01-01

    Some geometric behaviours of complete solutions to mean curvature flow before the singu-larities occur are studied. The author obtains the estimates of the rate of the distance betweentwo fixed points and the derivatives of the second fundamental form. By use of a new maximumprinciple, some geometric properties at infinity are obtained.

  5. Cosmological models with positive scalar spatial curvature and Λ>0

    Science.gov (United States)

    Ponce de Leon, J.

    1987-12-01

    Some exact spherically symmetric solutions of the Einstein field equations with Λ>0 and positive three-curvature are given. They have reasonable physical properties and represent universes which do not undergo inflation but have a non-de Sitter behaviour for large times. This paper extends some previous results in the literature. Permanent address: Apartado 2816, Caracas 1010-A, Venezuela.

  6. Critical dimension of strings with an extrinsic curvature

    International Nuclear Information System (INIS)

    Matsuki, T.; Viswanathan, K.S.

    1988-01-01

    The conformal anomaly is calculated by using the path-integral method to determine the critical dimension for a string theory with an extrinsic curvature by appropriately defining the first-order form of this Lagrangian. The critical dimension, defined by the vanishing of the Liouville kinetic term, is found to be D = 26, the same as for the ordinary bosonic string theory

  7. Distributional curvature of time-dependent cosmic strings

    OpenAIRE

    Wilson, J P

    1997-01-01

    Colombeau's theory of generalised functions is used to calculate the contributions, at the rotation axis, to the distributional curvature for a time-dependent radiating cosmic string, and hence the mass per unit length of the string source. This mass per unit length is compared with the mass at null infinity, giving evidence for a global energy conservation law.

  8. Automatic quantification of local and global articular cartilage surface curvature

    DEFF Research Database (Denmark)

    Folkesson, Jenny; Dam, Erik B; Olsen, Ole F

    2008-01-01

    The objective of this study was to quantitatively assess the surface curvature of the articular cartilage from low-field magnetic resonance imaging (MRI) data, and to investigate its role in populations with varying radiographic signs of osteoarthritis (OA), cross-sectionally and longitudinally...

  9. Directable weathering of concave rock using curvature estimation.

    Science.gov (United States)

    Jones, Michael D; Farley, McKay; Butler, Joseph; Beardall, Matthew

    2010-01-01

    We address the problem of directable weathering of exposed concave rock for use in computer-generated animation or games. Previous weathering models that admit concave surfaces are computationally inefficient and difficult to control. In nature, the spheroidal and cavernous weathering rates depend on the surface curvature. Spheroidal weathering is fastest in areas with large positive mean curvature and cavernous weathering is fastest in areas with large negative mean curvature. We simulate both processes using an approximation of mean curvature on a voxel grid. Both weathering rates are also influenced by rock durability. The user controls rock durability by editing a durability graph before and during weathering simulation. Simulations of rockfall and colluvium deposition further improve realism. The profile of the final weathered rock matches the shape of the durability graph up to the effects of weathering and colluvium deposition. We demonstrate the top-down directability and visual plausibility of the resulting model through a series of screenshots and rendered images. The results include the weathering of a cube into a sphere and of a sheltered inside corner into a cavern as predicted by the underlying geomorphological models.

  10. Generalized Curvature-Matter Couplings in Modified Gravity

    Directory of Open Access Journals (Sweden)

    Tiberiu Harko

    2014-07-01

    Full Text Available In this work, we review a plethora of modified theories of gravity with generalized curvature-matter couplings. The explicit nonminimal couplings, for instance, between an arbitrary function of the scalar curvature R and the Lagrangian density of matter, induces a non-vanishing covariant derivative of the energy-momentum tensor, implying non-geodesic motion and, consequently, leads to the appearance of an extra force. Applied to the cosmological context, these curvature-matter couplings lead to interesting phenomenology, where one can obtain a unified description of the cosmological epochs. We also consider the possibility that the behavior of the galactic flat rotation curves can be explained in the framework of the curvature-matter coupling models, where the extra terms in the gravitational field equations modify the equations of motion of test particles and induce a supplementary gravitational interaction. In addition to this, these models are extremely useful for describing dark energy-dark matter interactions and for explaining the late-time cosmic acceleration.

  11. Curvature-induced symmetry breaking in nonlinear Schrodinger models

    DEFF Research Database (Denmark)

    Gaididei, Yuri Borisovich; Mingaleev, S. F.; Christiansen, Peter Leth

    2000-01-01

    We consider a curved chain of nonlinear oscillators and show that the interplay of curvature and nonlinearity leads to a symmetry breaking when an asymmetric stationary state becomes energetically more favorable than a symmetric stationary state. We show that the energy of localized states...

  12. Other Earths: Search for Life and the Constant Curvature

    Directory of Open Access Journals (Sweden)

    Khoshyaran M. M.

    2015-07-01

    Full Text Available The objective of this paper is to propose a search methodology for finding other exactly similar earth like planets (or sister earths. The theory is based on space consisting of Riemann curves or highways. A mathematical model based on constant curvature, a moving frame bundle, and gravitational dynamics is introduced.

  13. Papapetrou's naked singularity is a strong curvature singularity

    International Nuclear Information System (INIS)

    Hollier, G.P.

    1986-01-01

    Following Papapetrou [1985, a random walk in General Relativity ed. J. Krishna-Rao (New Delhi: Wiley Eastern)], a spacetime with a naked singularity is analysed. This singularity is shown to be a strong curvature singularity and thus a counterexample to a censorship conjecture. (author)

  14. Comparison and analysis of membrane fouling between flocculent sludge membrane bioreactor and granular sludge membrane bioreactor.

    Directory of Open Access Journals (Sweden)

    Wang Jing-Feng

    Full Text Available The goal of this study is to investigate the effect of inoculating granules on reducing membrane fouling. In order to evaluate the differences in performance between flocculent sludge and aerobic granular sludge in membrane reactors (MBRs, two reactors were run in parallel and various parameters related to membrane fouling were measured. The results indicated that specific resistance to the fouling layer was five times greater than that of mixed liquor sludge in the granular MBR. The floc sludge more easily formed a compact layer on the membrane surface, and increased membrane resistance. Specifically, the floc sludge had a higher moisture content, extracellular polymeric substances concentration, and negative surface charge. In contrast, aerobic granules could improve structural integrity and strength, which contributed to the preferable permeate performance. Therefore, inoculating aerobic granules in a MBR presents an effective method of reducing the membrane fouling associated with floc sludge the perspective of from the morphological characteristics of microbial aggregates.

  15. Gaussian curvature elasticity determined from global shape transformations and local stress distributions: a comparative study using the MARTINI model.

    Science.gov (United States)

    Hu, Mingyang; de Jong, Djurre H; Marrink, Siewert J; Deserno, Markus

    2013-01-01

    We calculate the Gaussian curvature modulus kappa of a systematically coarse-grained (CG) one-component lipid membrane by applying the method recently proposed by Hu et al. [Biophys. J., 2012, 102, 1403] to the MARTINI representation of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). We find the value kappa/kappa = -1.04 +/- 0.03 for the elastic ratio between the Gaussian and the mean curvature modulus and deduce kappa(m)/kappa(m) = -0.98 +/- 0.09 for the monolayer elastic ratio, where the latter is based on plausible assumptions for the distance z0 of the monolayer neutral surface from the bilayer midplane and the spontaneous lipid curvature K(0m). By also analyzing the lateral stress profile sigma0(z) of our system, two other lipid types and pertinent data from the literature, we show that determining K(0m) and kappa through the first and second moment of sigma0(z) gives rise to physically implausible values for these observables. This discrepancy, which we previously observed for a much simpler CG model, suggests that the moment conditions derived from simple continuum assumptions miss the effect of physically important correlations in the lipid bilayer.

  16. Remarks on the boundary curve of a constant mean curvature topological disc

    DEFF Research Database (Denmark)

    Brander, David; Lopéz, Rafael

    2017-01-01

    We discuss some consequences of the existence of the holomorphic quadratic Hopf differential on a conformally immersed constant mean curvature topological disc with analytic boundary. In particular, we derive a formula for the mean curvature as a weighted average of the normal curvature of the bo......We discuss some consequences of the existence of the holomorphic quadratic Hopf differential on a conformally immersed constant mean curvature topological disc with analytic boundary. In particular, we derive a formula for the mean curvature as a weighted average of the normal curvature...

  17. Transitivity of Preferences

    Science.gov (United States)

    Regenwetter, Michel; Dana, Jason; Davis-Stober, Clintin P.

    2011-01-01

    Transitivity of preferences is a fundamental principle shared by most major contemporary rational, prescriptive, and descriptive models of decision making. To have transitive preferences, a person, group, or society that prefers choice option "x" to "y" and "y" to "z" must prefer "x" to…

  18. Phase separation and shape deformation of two-phase membranes

    International Nuclear Information System (INIS)

    Jiang, Y.; Lookman, T.; Saxena, A.

    2000-01-01

    Within a coupled-field Ginzburg-Landau model we study analytically phase separation and accompanying shape deformation on a two-phase elastic membrane in simple geometries such as cylinders, spheres, and tori. Using an exact periodic domain wall solution we solve for the shape and phase separating field, and estimate the degree of deformation of the membrane. The results are pertinent to preferential phase separation in regions of differing curvature on a variety of vesicles. (c) 2000 The American Physical Society

  19. Physical and Geometric Interpretations of the Riemann Tensor, Ricci Tensor, and Scalar Curvature

    OpenAIRE

    Loveridge, Lee C.

    2004-01-01

    Various interpretations of the Riemann Curvature Tensor, Ricci Tensor, and Scalar Curvature are described. Also, the physical meanings of the Einstein Tensor and Einstein's Equations are discussed. Finally a derivation of Newtonian Gravity from Einstein's Equations is given.

  20. Membrane shape modulates transmembrane protein distribution.

    Science.gov (United States)

    Aimon, Sophie; Callan-Jones, Andrew; Berthaud, Alice; Pinot, Mathieu; Toombes, Gilman E S; Bassereau, Patricia

    2014-01-27

    Although membrane shape varies greatly throughout the cell, the contribution of membrane curvature to transmembrane protein targeting is unknown because of the numerous sorting mechanisms that take place concurrently in cells. To isolate the effect of membrane shape, we used cell-sized giant unilamellar vesicles (GUVs) containing either the potassium channel KvAP or the water channel AQP0 to form membrane nanotubes with controlled radii. Whereas the AQP0 concentrations in flat and curved membranes were indistinguishable, KvAP was enriched in the tubes, with greater enrichment in more highly curved membranes. Fluorescence recovery after photobleaching measurements showed that both proteins could freely diffuse through the neck between the tube and GUV, and the effect of each protein on membrane shape and stiffness was characterized using a thermodynamic sorting model. This study establishes the importance of membrane shape for targeting transmembrane proteins and provides a method for determining the effective shape and flexibility of membrane proteins. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Membrane Biophysics

    CERN Document Server

    Ashrafuzzaman, Mohammad

    2013-01-01

    Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doors for high-level pharmaceutical approaches towards fighting membrane- and cell-related diseases.

  2. A 1 + 5-dimensional gravitational-wave solution. Curvature singularity and spacetime singularity

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yu-Zhu [Tianjin University, Department of Physics, Tianjin (China); Li, Wen-Du [Tianjin University, Department of Physics, Tianjin (China); Nankai University, Theoretical Physics Division, Chern Institute of Mathematics, Tianjin (China); Dai, Wu-Sheng [Nankai University, Theoretical Physics Division, Chern Institute of Mathematics, Tianjin (China); Nankai University and Tianjin University, LiuHui Center for Applied Mathematics, Tianjin (China)

    2017-12-15

    We solve a 1 + 5-dimensional cylindrical gravitational-wave solution of the Einstein equation, in which there are two curvature singularities. Then we show that one of the curvature singularities can be removed by an extension of the spacetime. The result exemplifies that the curvature singularity is not always a spacetime singularity; in other words, the curvature singularity cannot serve as a criterion for spacetime singularities. (orig.)

  3. Effect of nano-scale curvature on the intrinsic blood coagulation system

    Science.gov (United States)

    Kushida, Takashi; Saha, Krishnendu; Subramani, Chandramouleeswaran; Nandwana, Vikas; Rotello, Vincent M.

    2014-01-01

    The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation ‘silent’ surface, while nanoparticles with lower surface curvature shows denaturation and concomitant coagulation. PMID:25341004

  4. Extrinsic Isoperimetric Analysis on Submanifolds with Curvatures bounded from below

    DEFF Research Database (Denmark)

    Markvorsen, Steen; Palmer, Vicente

    2010-01-01

    and on the radial part of the intrinsic unit normals at the boundaries of the extrinsic spheres, respectively. In the same vein we also establish lower bounds on the mean exit time for Brownian motions in the extrinsic balls, i.e. lower bounds for the time it takes (on average) for Brownian particles to diffuse......We obtain upper bounds for the isoperimetric quotients of extrinsic balls of submanifolds in ambient spaces which have a lower bound on their radial sectional curvatures. The submanifolds are themselves only assumed to have lower bounds on the radial part of the mean curvature vector field...... within the extrinsic ball from a given starting point before they hit the boundary of the extrinsic ball. In those cases, where we may extend our analysis to hold all the way to infinity, we apply a capacity comparison technique to obtain a sufficient condition for the submanifolds to be parabolic, i...

  5. Curvature effects on carbon nanomaterials: Exohedral versus endhohedral supercapacitors

    Energy Technology Data Exchange (ETDEWEB)

    Huang, J; Sumpter, B. G.; Meunier, V.; Yushin, G.; Portet, C.; Gogotsi, Y.

    2011-01-31

    Capacitive energy storage mechanisms in nanoporous carbon supercapacitors hinge on endohedral interactions in carbon materials with macro-, meso-, and micropores that have negative surface curvature. In this article, we show that because of the positive curvature found in zero-dimensional carbon onions or one-dimensional carbon nanotube arrays, exohedral interactions cause the normalized capacitance to increase with decreasing particle size or tube diameter, in sharp contrast to the behavior of nanoporous carbon materials. This finding is in good agreement with the trend of recent experimental data. Our analysis suggests that electrical energy storage can be improved by exploiting the highly curved surfaces of carbon nanotube arrays with diameters on the order of 1 nm.

  6. Non-linear realizations and higher curvature supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Farakos, F. [Dipartimento di Fisica e Astronomia ' ' Galileo Galilei' ' , Universita di Padova (Italy); INFN, Sezione di Padova (Italy); Ferrara, S. [Department of Theoretical Physics, Geneva (Switzerland); INFN - Laboratori Nazionali di Frascati, Frascati (Italy); Department of Physics and Astronomy, Mani L. Bhaumik Institute for Theoretical Physics, U.C.L.A., Los Angeles, CA (United States); Kehagias, A. [Physics Division, National Technical University of Athens (Greece); Luest, D. [Arnold Sommerfeld Center for Theoretical Physics, Muenchen (Germany); Max-Planck-Institut fuer Physik, Muenchen (Germany)

    2017-12-15

    We focus on non-linear realizations of local supersymmetry as obtained by using constrained superfields in supergravity. New constraints, beyond those of rigid supersymmetry, are obtained whenever curvature multiplets are affected as well as higher derivative interactions are introduced. In particular, a new constraint, which removes a very massive gravitino is introduced, and in the rigid limit it merely reduces to an explicit supersymmetry breaking. Higher curvature supergravities free of ghosts and instabilities are also obtained in this way. Finally, we consider direct coupling of the goldstino multiplet to the super Gauss-Bonnet multiplet and discuss the emergence of a new scalar degree of freedom. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  7. Curvature properties of four-dimensional Walker metrics

    International Nuclear Information System (INIS)

    Chaichi, M; Garcia-Rio, E; Matsushita, Y

    2005-01-01

    A Walker n-manifold is a semi-Riemannian manifold, which admits a field of parallel null r-planes, r ≤ n/2. In the present paper we study curvature properties of a Walker 4-manifold (M, g) which admits a field of parallel null 2-planes. The metric g is necessarily of neutral signature (+ + - -). Such a Walker 4-manifold is the lowest dimensional example not of Lorentz type. There are three functions of coordinates which define a Walker metric. Some recent work shows that a Walker 4-manifold of restricted type whose metric is characterized by two functions exhibits a large variety of symplectic structures, Hermitian structures, Kaehler structures, etc. For such a restricted Walker 4-manifold, we shall study mainly curvature properties, e.g., conditions for a Walker metric to be Einstein, Osserman, or locally conformally flat, etc. One of our main results is the exact solutions to the Einstein equations for a restricted Walker 4-manifold

  8. Curvature effects in carbon nanomaterials: Exohedral versus endohedral supercapacitors

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Jingsong [ORNL; Sumpter, Bobby G [ORNL; Meunier, Vincent [ORNL; Gogotsi, Yury G. [Drexel University; Yushin, Gleb [Georgia Institute of Technology; Portet, Cristelle [Drexel University

    2010-01-01

    Capacitive energy storage mechanisms in nanoporous carbon supercapacitors hinge on endohedral interactions in carbon materials with macro-, meso-, and micropores that have negative surface curvature. In this article, we show that because of the positive curvature found in zero-dimensional carbon onions or one-dimensional carbon nanotube arrays, exohedral interactions cause the normalized capacitance to increase with decreasing particle size or tube diameter, in sharp contrast to the behavior of nanoporous carbon materials. This finding is in good agreement with the trend of recent experimental data. Our analysis suggests that electrical energy storage can be improved by exploiting the highly curved surfaces of carbon nanotube arrays with diameters on the order of 1 nm.

  9. On M-theory fourfold vacua with higher curvature terms

    International Nuclear Information System (INIS)

    Grimm, Thomas W.; Pugh, Tom G.; Weißenbacher, Matthias

    2015-01-01

    We study solutions to the eleven-dimensional supergravity action, including terms quartic and cubic in the Riemann curvature, that admit an eight-dimensional compact space. The internal background is found to be a conformally Kähler manifold with vanishing first Chern class. The metric solution, however, is non-Ricci-flat even when allowing for a conformal rescaling including the warp factor. This deviation is due to the possible non-harmonicity of the third Chern-form in the leading order Ricci-flat metric. We present a systematic derivation of the background solution by solving the Killing spinor conditions including higher curvature terms. These are translated into first-order differential equations for a globally defined real two-form and complex four-form on the fourfold. We comment on the supersymmetry properties of the described solutions

  10. Substrate Curvature Regulates Cell Migration -A Computational Study

    Science.gov (United States)

    He, Xiuxiu; Jiang, Yi

    Cell migration in host microenvironment is essential to cancer etiology, progression and metastasis. Cellular processes of adhesion, cytoskeletal polymerization, contraction, and matrix remodeling act in concert to regulate cell migration, while local extracellular matrix architecture modulate these processes. In this work we study how stromal microenvironment with native and cell-derived curvature at micron-meter scale regulate cell motility pattern. We developed a 3D model of single cell migration on a curved substrate. Mathematical analysis of cell morphological adaption to the cell-substrate interface shows that cell migration on convex surfaces deforms more than on concave surfaces. Both analytical and simulation results show that curved surfaces regulate the cell motile force for cell's protruding front through force balance with focal adhesion and cell contraction. We also found that cell migration on concave substrates is more persistent. These results offer a novel biomechanical explanation to substrate curvature regulation of cell migration. NIH 1U01CA143069.

  11. Glauber theory and the quantum coherence of curvature inhomogeneities

    CERN Document Server

    Giovannini, Massimo

    2017-01-12

    The curvature inhomogeneities are systematically scrutinized in the framework of the Glauber approach. The amplified quantum fluctuations of the scalar and tensor modes of the geometry are shown to be first-order coherent while the interference of the corresponding intensities is larger than in the case of Bose-Einstein correlations. After showing that the degree of second-order coherence does not suffice to characterize unambiguously the curvature inhomogeneities, we argue that direct analyses of the degrees of third and fourth-order coherence are necessary to discriminate between different correlated states and to infer more reliably the statistical properties of the large-scale fluctuations. We speculate that the moments of the multiplicity distributions of the relic phonons might be observationally accessible thanks to new generations of instruments able to count the single photons of the Cosmic Microwave Background in the THz region.

  12. Generating ekpyrotic curvature perturbations before the big bang

    International Nuclear Information System (INIS)

    Lehners, Jean-Luc; Turok, Neil; McFadden, Paul; Steinhardt, Paul J.

    2007-01-01

    We analyze a general mechanism for producing a nearly scale-invariant spectrum of cosmological curvature perturbations during a contracting phase preceding a big bang, which can be entirely described using 4D effective field theory. The mechanism, based on first producing entropic perturbations and then converting them to curvature perturbations, can be naturally incorporated in cyclic and ekpyrotic models in which the big bang is modeled as a brane collision, as well as other types of cosmological models with a pre-big bang phase. We show that the correct perturbation amplitude can be obtained and that the spectral tilt n s tends to range from slightly blue to red, with 0.97 s <1.02 for the simplest models, a range compatible with current observations but shifted by a few percent towards the blue compared to the prediction of the simplest, large-field inflationary models

  13. Quantum Deformations and Superintegrable Motions on Spaces with Variable Curvature

    Directory of Open Access Journals (Sweden)

    Orlando Ragnisco

    2007-02-01

    Full Text Available An infinite family of quasi-maximally superintegrable Hamiltonians with a common set of (2N-3 integrals of the motion is introduced. The integrability properties of all these Hamiltonians are shown to be a consequence of a hidden non-standard quantum sl(2,R Poisson coalgebra symmetry. As a concrete application, one of this Hamiltonians is shown to generate the geodesic motion on certain manifolds with a non-constant curvature that turns out to be a function of the deformation parameter z. Moreover, another Hamiltonian in this family is shown to generate geodesic motions on Riemannian and relativistic spaces all of whose sectional curvatures are constant and equal to the deformation parameter z. This approach can be generalized to arbitrary dimension by making use of coalgebra symmetry.

  14. Imprint of spatial curvature on inflation power spectrum

    International Nuclear Information System (INIS)

    Masso, Eduard; Zsembinszki, Gabriel; Mohanty, Subhendra; Nautiyal, Akhilesh

    2008-01-01

    If the Universe had a large curvature before inflation there is a deviation from the scale invariant perturbations of the inflaton at the beginning of inflation. This may have some effect on the cosmic microwave background anisotropy at large angular scales. We calculate the density perturbations for both open and closed universe cases using the Bunch-Davies vacuum condition on the initial state. We use our power spectrum to calculate the temperature anisotropy spectrum and compare the results with the Wilkinson microwave anisotropy map five year data. We find that our power spectrum gives a lower quadrupole anisotropy when Ω-1>0, but matches the temperature anisotropy calculated from the standard Ratra-Peebles power spectrum at large l. The determination of spatial curvature from temperature anisotropy data is not much affected by the different power spectra which arise from the choice of different boundary conditions for the inflaton perturbation.

  15. Thermodynamic curvature of soft-sphere fluids and solids

    Science.gov (United States)

    Brańka, A. C.; Pieprzyk, S.; Heyes, D. M.

    2018-02-01

    The influence of the strength of repulsion between particles on the thermodynamic curvature scalar R for the fluid and solid states is investigated for particles interacting with the inverse power (r-n) potential, where r is the pair separation and 1 /n is the softness. Exact results are obtained for R in certain limiting cases, and the R behavior determined for the systems in the fluid and solid phases. It is found that in such systems the thermodynamic curvature can be positive for very soft particles, negative for steeply repulsive (or large n ) particles across almost the entire density range, and can change sign between negative and positive at a certain density. The relationship between R and the form of the interaction potential is more complex than previously suggested, and it may be that R is an indicator of the relative importance of energy and entropy contributions to the thermodynamic properties of the system.

  16. Spheres of influence: Porphyromonas gingivalis outer membrane vesicles.

    Science.gov (United States)

    Gui, M J; Dashper, S G; Slakeski, N; Chen, Y-Y; Reynolds, E C

    2016-10-01

    Outer membrane vesicles (OMVs) are asymmetrical single bilayer membranous nanostructures produced by Gram-negative bacteria important for bacterial interaction with the environment. Porphyromonas gingivalis, a keystone pathogen associated with chronic periodontitis, produces OMVs that act as a virulence factor secretion system contributing to its pathogenicity. Despite their biological importance, the mechanisms of OMV biogenesis have not been fully elucidated. The ~14 times more curvature of the OMV membrane than cell outer membrane (OM) indicates that OMV biogenesis requires energy expenditure for significant curvature of the OMV membrane. In P. gingivalis, we propose that this may be achieved by upregulating the production of certain inner or outer leaflet lipids, which causes localized outward curvature of the OM. This results in selection of anionic lipopolysaccharide (A-LPS) and associated C-terminal domain (CTD) -family proteins on the outer surface due to their ability to accommodate the curvature. Deacylation of A-LPS may further enable increased curvature leading to OMV formation. Porphyromonas gingivalis OMVs that are selectively enriched in CTD-family proteins, largely the gingipains, can support bacterial coaggregation, promote biofilm development and act as an intercessor for the transport of non-motile bacteria by motile bacteria. The P. gingivalis OMVs are also believed to contribute to host interaction and colonization, evasion of immune defense mechanisms, and destruction of periodontal tissues. They may be crucial for both micro- and macronutrient capture, especially heme and probably other assimilable compounds for its own benefit and that of the wider biofilm community. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Reheating via a generalized nonminimal coupling of curvature to matter

    International Nuclear Information System (INIS)

    Bertolami, Orfeu; Frazao, Pedro; Paramos, Jorge

    2011-01-01

    In this work, one shows that a generalized nonminimal coupling between geometry and matter is compatible with Starobinsky inflation and leads to a successful process of preheating, a reheating scenario based on the production of massive particles via parametric resonance. The model naturally extends the usual preheating mechanism, which resorts to an ad hoc scalar curvature-dependent mass term for a scalar field χ, and also encompasses a previously studied preheating channel based upon a nonstandard kinetic term.

  18. On the concircular curvature tensor of Riemannian manifolds

    International Nuclear Information System (INIS)

    Rahman, M.S.; Lal, S.

    1990-06-01

    Definition of the concircular curvature tensor, Z hijk , along with Z-tensor, Z ij , is given and some properties of Z hijk are described. Tensors identical with Z hijk are shown. A necessary and sufficient condition that a Riemannian V n has zero Z-tensor is found. A number of theorems on concircular symmetric space, concircular recurrent space (Z n -space) and Z n -space with zero Z-tensor are deduced. (author). 6 refs

  19. Investigating undergraduate students’ ideas about the curvature of the Universe

    Directory of Open Access Journals (Sweden)

    Kim Coble

    2018-06-01

    Full Text Available [This paper is part of the Focused Collection on Astronomy Education Research.] As part of a larger project studying undergraduate students’ understanding of cosmology, we explored students’ ideas about the curvature of the Universe. We investigated preinstruction ideas held by introductory astronomy (ASTRO 101 students at three participating universities and postinstruction ideas at one. Through thematic analysis of responses to questions on three survey forms and preinstruction interviews, we found that prior to instruction a significant fraction of students said the Universe is round. Students’ reasoning for this included that the Universe contains round objects, therefore it must also be round, or an incorrect idea that the big bang theory describes an explosion from a central point. We also found that a majority of students think that astronomers use the term curvature to describe properties, such as dimensions, angles, or size, of the Universe or objects in the Universe, or that astronomers use the term curvature to describe the bending of space due to gravity. Students are skeptical that the curvature of the Universe can be measured, to a greater or lesser degree depending on question framing. Postinstruction responses to a multiple-choice exam question and interviews at one university indicate that students are more likely to correctly respond that the Universe as a whole is not curved postinstruction, though the idea that the Universe is round still persists for some students. While we see no evidence that priming with an elliptical or rectangular map of the cosmic microwave background on a postinstruction exam affects responses, students do cite visualizations such as diagrams among the reasons for their responses in preinstruction surveys.

  20. Torsion and curvature in higher dimensional supergravity theories

    International Nuclear Information System (INIS)

    Smith, A.W.; Pontificia Univ. Catolica do Rio de Janeiro

    1983-01-01

    This work is an extension of Dragon's theorems to higher dimensional space-time. It is shown that the first set of Bianchi identities allow us to express the curvature components in terms of torsion components and its covariant derivatives. It is also shown that the second set of Bianchi identities does not give any new information which is not already contained in the first one. (Author) [pt

  1. Global and local curvature in density functional theory.

    Science.gov (United States)

    Zhao, Qing; Ioannidis, Efthymios I; Kulik, Heather J

    2016-08-07

    Piecewise linearity of the energy with respect to fractional electron removal or addition is a requirement of an electronic structure method that necessitates the presence of a derivative discontinuity at integer electron occupation. Semi-local exchange-correlation (xc) approximations within density functional theory (DFT) fail to reproduce this behavior, giving rise to deviations from linearity with a convex global curvature that is evidence of many-electron, self-interaction error and electron delocalization. Popular functional tuning strategies focus on reproducing piecewise linearity, especially to improve predictions of optical properties. In a divergent approach, Hubbard U-augmented DFT (i.e., DFT+U) treats self-interaction errors by reducing the local curvature of the energy with respect to electron removal or addition from one localized subshell to the surrounding system. Although it has been suggested that DFT+U should simultaneously alleviate global and local curvature in the atomic limit, no detailed study on real systems has been carried out to probe the validity of this statement. In this work, we show when DFT+U should minimize deviations from linearity and demonstrate that a "+U" correction will never worsen the deviation from linearity of the underlying xc approximation. However, we explain varying degrees of efficiency of the approach over 27 octahedral transition metal complexes with respect to transition metal (Sc-Cu) and ligand strength (CO, NH3, and H2O) and investigate select pathological cases where the delocalization error is invisible to DFT+U within an atomic projection framework. Finally, we demonstrate that the global and local curvatures represent different quantities that show opposing behavior with increasing ligand field strength, and we identify where these two may still coincide.

  2. Reflectionlessness, kurtosis and top curvature of potential barriers

    International Nuclear Information System (INIS)

    Ahmed, Zafar

    2006-01-01

    Apart from the rectangular barrier, other barriers having a single maximum generally display reflectivity, R(E), as a smoothly decreasing function of energy. We conjecture that symmetric potential barriers with a single maximum entail zeros or sharp minima in R(E) provided they have either their coefficient of kurtosis lying in the range (1.8, 3.0), or their top curvature as zero, or both

  3. Tachyonless models of relativistic particles with curvature and torsion

    International Nuclear Information System (INIS)

    Kuznetsov, Yu.A.; Plyushchaj, M.S.

    1992-01-01

    The problem of construction (2+1)-dimensional tachyonless models of relativistic particles with an action depending on the world-trajectory curvature and torsion is investigated. The special class of models, described by maximum symmetric action and comprising only spin internal degrees of freedom is found. The examples of systems from the special class are given, whose classical and quantum spectra contain only massive states. 23 refs

  4. Curvature of super Diff(S1)/S1

    International Nuclear Information System (INIS)

    Oh, P.; Ramond, P.

    1987-01-01

    Motivated by the work of Bowick and Rajeev, we calculate the curvature of the infinite-dimensional flag manifolds Diff(S 1 )/S 1 and Super Diff(S 1 )/S 1 using standard finite-dimensional coset space techniques. We regularize the infinite by ζ-function regularization and recover the conformal and superconformal anomalies respectively for a specific choice of the torsion. (orig.)

  5. ON THE CURVATURE OF DUST LANES IN GALACTIC BARS

    International Nuclear Information System (INIS)

    Comeron, Sebastien; MartInez-Valpuesta, Inma; Knapen, Johan H.; Beckman, John E.

    2009-01-01

    We test the theoretical prediction that the straightest dust lanes in bars are found in strongly barred galaxies, or more specifically, that the degree of curvature of the dust lanes is inversely proportional to the strength of the bar. The test uses archival images of barred galaxies for which a reliable nonaxisymmetric torque parameter (Q b ) and the radius at which Q b has been measured (r(Q b )) have been published in the literature. Our results confirm the theoretical prediction but show a large spread that cannot be accounted for by measurement errors. We simulate 238 galaxies with different bar and bulge parameters in order to investigate the origin of the spread in the dust lane curvature versus Q b relation. From these simulations, we conclude that the spread is greatly reduced when describing the bar strength as a linear combination of the bar parameters Q b and the quotient of the major and minor axes of the bar, a/b. Thus, we conclude that the dust lane curvature is predominantly determined by the parameters of the bar.

  6. Curvature profiles as initial conditions for primordial black hole formation

    International Nuclear Information System (INIS)

    Polnarev, Alexander G; Musco, Ilia

    2007-01-01

    This work is part of an ongoing research programme to study possible primordial black hole (PBH) formation during the radiation-dominated era of the early universe. Working within spherical symmetry, we specify an initial configuration in terms of a curvature profile, which represents initial conditions for the large amplitude metric perturbations, away from the homogeneous Friedmann-Robertson-Walker model, which are required for PBH formation. Using an asymptotic quasi-homogeneous solution, we relate the curvature profile with the density and velocity fields, which at an early enough time, when the length scale of the configuration is much larger than the cosmological horizon, can be treated as small perturbations of the background values. We present general analytic solutions for the density and velocity profiles. These solutions enable us to consider in a self-consistent way the formation of PBHs in a wide variety of cosmological situations with the cosmological fluid being treated as an arbitrary mixture of different components with different equations of state. We obtain the analytical solutions for the density and velocity profiles as functions of the initial time. We then use two different parametrizations for the curvature profile and follow numerically the evolution of initial configurations

  7. Generic Properties of Curvature Sensing through Vision and Touch

    Directory of Open Access Journals (Sweden)

    Birgitta Dresp-Langley

    2013-01-01

    Full Text Available Generic properties of curvature representations formed on the basis of vision and touch were examined as a function of mathematical properties of curved objects. Virtual representations of the curves were shown on a computer screen for visual scaling by sighted observers (experiment 1. Their physical counterparts were placed in the two hands of blindfolded and congenitally blind observers for tactile scaling. The psychophysical data show that curvature representations in congenitally blind individuals, who never had any visual experience, and in sighted observers, who rely on vision most of the time, are statistically linked to the same mathematical properties of the curves. The perceived magnitude of object curvature, sensed through either vision or touch, is related by a mathematical power law, with similar exponents for the two sensory modalities, to the aspect ratio of the curves, a scale invariant geometric property. This finding supports biologically motivated models of sensory integration suggesting a universal power law for the adaptive brain control and balance of motor responses to environmental stimuli from any sensory modality.

  8. Finger vein extraction using gradient normalization and principal curvature

    Science.gov (United States)

    Choi, Joon Hwan; Song, Wonseok; Kim, Taejeong; Lee, Seung-Rae; Kim, Hee Chan

    2009-02-01

    Finger vein authentication is a personal identification technology using finger vein images acquired by infrared imaging. It is one of the newest technologies in biometrics. Its main advantage over other biometrics is the low risk of forgery or theft, due to the fact that finger veins are not normally visible to others. Extracting finger vein patterns from infrared images is the most difficult part in finger vein authentication. Uneven illumination, varying tissues and bones, and changes in the physical conditions and the blood flow make the thickness and brightness of the same vein different in each acquisition. Accordingly, extracting finger veins at their accurate positions regardless of their thickness and brightness is necessary for accurate personal identification. For this purpose, we propose a new finger vein extraction method which is composed of gradient normalization, principal curvature calculation, and binarization. As local brightness variation has little effect on the curvature and as gradient normalization makes the curvature fairly uniform at vein pixels, our method effectively extracts finger vein patterns regardless of the vein thickness or brightness. In our experiment, the proposed method showed notable improvement as compared with the existing methods.

  9. Berry Curvature and Nonlocal Transport Characteristics of Antidot Graphene

    Directory of Open Access Journals (Sweden)

    Jie Pan

    2017-09-01

    Full Text Available Antidot graphene denotes a monolayer of graphene structured by a periodic array of holes. Its energy dispersion is known to display a gap at the Dirac point. However, since the degeneracy between the A and B sites is preserved, antidot graphene cannot be described by the 2D massive Dirac equation, which is suitable for systems with an inherent A/B asymmetry. From inversion and time-reversal-symmetry considerations, antidot graphene should therefore have zero Berry curvature. In this work, we derive the effective Hamiltonian of antidot graphene from its tight-binding wave functions. The resulting Hamiltonian is a 4×4 matrix with a nonzero intervalley scattering term, which is responsible for the gap at the Dirac point. Furthermore, nonzero Berry curvature is obtained from the effective Hamiltonian, owing to the double degeneracy of the eigenfunctions. The topological manifestation is shown to be robust against randomness perturbations. Since the Berry curvature is expected to induce a transverse conductance, we have experimentally verified this feature through nonlocal transport measurements, by fabricating three antidot graphene samples with a triangular array of holes, a fixed periodicity of 150 nm, and hole diameters of 100, 80, and 60 nm. All three samples display topological nonlocal conductance, with excellent agreement with the theory predictions.

  10. Curvature-driven instabilities in the Elmo Bumpy Torus (EBT)

    International Nuclear Information System (INIS)

    Abe, H.; Spong, D.A.; Antonsen, T.M. Jr.; Tsang, K.T.; Nguyen, K.T.

    1982-01-01

    Curvature-driven instabilities are analyzed for an EBT configuration which consists of plasma interacting with a hot electron ring whose drift frequencies are larger than the growth rates predicted from conventional magnetohydrodynamic (MHD) theory. Stability criteria are obtained for five possible modes: the conventional hot electron interchange, a high-frequency hot electron interchange (at frequencies greater than the ion-cyclotron frequency), a compressional instability, a background plasma interchange, and an interacting pressure-driven interchange. A wide parameter regime for stable operation is found, which, however, severely deteriorates for a band of intermediate mode numbers. Finite Larmor radius effects can eliminate this deterioration; moreover, all short-wavelength curvature-driven modes are stabilized if the hot electron Larmor radius rho/sub h/ satisfies (kappa/sub perpendicular/rho/sub h/) 2 > 2Δ/[Rβ/sub h/(1 + P'/sub parallel//P'/sub perpendicular/)], where kappa/sub perpendicular/ is the transverse wavenumber, Δ is the ring half-width, R is the mid-plane radius of curvature, β/sub h/ is the hot electron beta value, and P' is the pressure gradient. Resonant wave-particle instabilities predicted by a new low frequency variational principle show that a variety of remnant instabilities may still persist

  11. Factors affecting root curvature of mandibular first molar

    International Nuclear Information System (INIS)

    Choi, Hang Moon; Yi, Won Jin; Heo, Min Suk; Kim, Jung Hwa; Choi, Soon Chul; Park, Tae Won

    2006-01-01

    To find the cause of root curvature by use of panoramic and lateral cephalometric radiograph. Twenty six 1st graders whose mandibular 1st molars just emerged into the mouth were selected. Panoramic and lateral cephalometric radiograph were taken at grade 1 and 6, longitudinally. In cephalometric radio graph, mandibular plane angle, ramus-occlusal place angle, gonial angle, and gonion-gnathion distance(Go-Gn distance) were measured. In panoramic radiograph, elongated root length and root angle were measured by means of digital subtraction radiography. Occlusal plane-tooth axis angle was measured, too. Pearson correlations were used to evaluate the relationships between root curvature and elongated length and longitudinal variations of all variables. Multiple regression equation using related variables was computed. The pearson correlation coefficient between curved angle and longitudinal variations of occlusal plane-tooth axis angle and ramus-occlusal plane angle was 0.350 and 0.401, respectively (p 1 +0.745X 2 (Y: root angle, X 1 : variation of occlusal plane-tooth axis angle, X 2 : variation of ramus-occlusal plane angle). It was suspected that the reasons of root curvature were change of tooth axis caused by contact with 2nd deciduous tooth and amount of mesial and superior movement related to change of occlusal plane

  12. Non-uniform dispersion of the source-sink relationship alters wavefront curvature.

    Directory of Open Access Journals (Sweden)

    Lucia Romero

    Full Text Available The distribution of cellular source-sink relationships plays an important role in cardiac propagation. It can lead to conduction slowing and block as well as wave fractionation. It is of great interest to unravel the mechanisms underlying evolution in wavefront geometry. Our goal is to investigate the role of the source-sink relationship on wavefront geometry using computer simulations. We analyzed the role of variability in the microscopic source-sink relationship in driving changes in wavefront geometry. The electrophysiological activity of a homogeneous isotropic tissue was simulated using the ten Tusscher and Panfilov 2006 action potential model and the source-sink relationship was characterized using an improved version of the Romero et al. safety factor formulation (SFm2. Our simulations reveal that non-uniform dispersion of the cellular source-sink relationship (dispersion along the wavefront leads to alterations in curvature. To better understand the role of the source-sink relationship in the process of wave formation, the electrophysiological activity at the initiation of excitation waves in a 1D strand was examined and the source-sink relationship was characterized using the two recently updated safety factor formulations: the SFm2 and the Boyle-Vigmond (SFVB definitions. The electrophysiological activity at the initiation of excitation waves was intimately related to the SFm2 profiles, while the SFVB led to several counterintuitive observations. Importantly, with the SFm2 characterization, a critical source-sink relationship for initiation of excitation waves was identified, which was independent of the size of the electrode of excitation, membrane excitability, or tissue conductivity. In conclusion, our work suggests that non-uniform dispersion of the source-sink relationship alters wavefront curvature and a critical source-sink relationship profile separates wave expansion from collapse. Our study reinforces the idea that the

  13. Membranes as separators of dispersed emulsion phases

    OpenAIRE

    Lefferts, A.G.

    1997-01-01

    The reuse or discharge of industrial waste waters, containing small fractions of dispersed oil, requires a purification treatment for which membranes can be used. If only little oil is present, removal of the dispersed phase might be preferable to the more commonly applied removal of the continuous phase. For this purpose dispersed phase separators can be applied, which combine the features of conventional coalescers and membrane filtration. The membrane surface promotes coalescence ...

  14. A preference for migration

    OpenAIRE

    Stark, Oded

    2007-01-01

    At least to some extent migration behavior is the outcome of a preference for migration. The pattern of migration as an outcome of a preference for migration depends on two key factors: imitation technology and migration feasibility. We show that these factors jointly determine the outcome of a preference for migration and we provide examples that illustrate how the prevalence and transmission of a migration-forming preference yield distinct migration patterns. In particular, the imitation of...

  15. Electrodiffusion of lipids on membrane surfaces.

    Science.gov (United States)

    Zhou, Y C

    2012-05-28

    Lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when the random lateral motion is mediated by the electrostatic interactions and membrane curvature. Although the lateral diffusion rates of lipids on membranes of various compositions are measured and the electrostatic free energies of predetermined protein-membrane-lipid systems can be computed, the process of the aggregation and the evolution to the electrostatically favorable states remain largely undetermined. Here we propose an electrodiffusion model, based on the variational principle of the free energy functional, for the self-consistent lateral drift-diffusion of multiple species of charged lipids on membrane surfaces. Finite sizes of lipids are modeled to enforce the geometrical constraint of the lipid concentration on membrane surfaces. A surface finite element method is developed to appropriate the Laplace-Beltrami operators in the partial differential equations of the model. Our model properly describes the saturation of lipids on membrane surfaces, and correctly predicts that the MARCKS peptide can consistently sequester three multivalent phosphatidylinositol 4,5-bisphosphate lipids through its basic amino acid residues, regardless of a wide range of the percentage of monovalent phosphatidylserine in the membrane.

  16. Preferences over Social Risk

    DEFF Research Database (Denmark)

    Harrison, Glenn W.; Lau, Morten; Rutström, E. Elisabet

    2013-01-01

    that subjects systematically reveal different risk attitudes in a social setting with no prior knowledge about the risk preferences of others compared to when they solely bear the consequences of the decision. However, we also find that subjects are significantly more risk averse when they know the risk......We elicit individual preferences over social risk. We identify the extent to which these preferences are correlated with preferences over individual risk and the well-being of others. We examine these preferences in the context of laboratory experiments over small, anonymous groups, although...... the methodological issues extend to larger groups that form endogenously (e.g., families, committees, communities). Preferences over social risk can be closely approximated by individual risk attitudes when subjects have no information about the risk preferences of other group members. We find no evidence...

  17. Holonomy Attractor Connecting Spaces of Different Curvature Responsible for ``Anomalies''

    Science.gov (United States)

    Binder, Bernd

    2009-03-01

    In this lecture paper we derive Magic Angle Precession (MAP) from first geometric principles. MAP can arise in situations, where precession is multiply related to spin, linearly by time or distance (dynamic phase, rolling, Gauss law) and transcendentally by the holonomy loop path (geometric phase). With linear spin-precession coupling, gyroscopes can be spun up and down to very high frequencies via low frequency holonomy control induced by external accelerations, which provides for extreme coupling strengths or "anomalies" that can be tested by the powerball or gyrotwister device. Geometrically, a gyroscopic manifold with spherical metric is tangentially aligned to a precession wave channel with conic or hyperbolic metric (like the relativistic Thomas precession). Transporting triangular spin/precession vector relations across the tangential boundary of contact with SO(3) Lorentz symmetry, we get extreme vector currents near the attractor fixed points in precession phase space, where spin currents remain intact while crossing the contact boundaries between regions of different curvature signature (-1, 0, +1). The problem can be geometrically solved by considering a curvature invariant triangular condition, which holds on surfaces with different curvature that are in contact and locally parallel. In this case two out of three angles are identical, whereas the third angle is different due to holonomy. If we require that the side length ratio corresponding to these angles are invariant we get a geodesic chaotic attractor, which is a cosine map cos(x)˜Mx in parameter space providing for fixed points, limit cycle bifurcations, and singularities. The situation could be quite natural and common in the context of vector currents in curved spacetime and gauge theories. MAP could even be part of the electromagnetic interaction, where the electric charge is the geometric U(1) precession spin current and gauge potential with magnetic effects given by extra rotations under the

  18. Cationic membranes complexed with oppositely charged microtubules: hierarchical self-assembly leading to bio-nanotubes

    International Nuclear Information System (INIS)

    Raviv, Uri; Needleman, Daniel J; Safinya, Cyrus R

    2006-01-01

    The self-assembly of microtubules and charged membranes has been studied, using x-ray diffraction and electron microscopy. Polyelectrolyte lipid complexes usually form structures templated by the lipid phase, when the polyelectrolyte curvature is much larger than the membrane spontaneous curvature. When the polyelectrolyte curvature approaches the membrane spontaneous curvature, as in microtubules, two types of new structures emerge. Depending on the conditions, vesicles either adsorb onto the microtubule, forming a 'beads on a rod' structure, or coat the microtubule, which now forms the template. Tubulin oligomers then coat the external lipid layer, forming a lipid protein nanotube. The tubulin oligomer coverage at the external layer is determined by the membrane charge density. The energy barrier between the beads on a rod and the lipid-protein nanotube states depends on the membrane bending rigidity and membrane charge density. By controlling the lipid/tubulin stoichiometry we can switch between lipid-protein nanotubes with open ends to lipid-protein nanotubes with closed end with lipid cups. This forms the basis for controlled drug encapsulation and release

  19. An Improved Method to Measure the Cosmic Curvature

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Jun-Jie; Wu, Xue-Feng, E-mail: jjwei@pmo.ac.cn [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2017-04-01

    In this paper, we propose an improved model-independent method to constrain the cosmic curvature by combining the most recent Hubble parameter H ( z ) and supernovae Ia (SNe Ia) data. Based on the H ( z ) data, we first use the model-independent smoothing technique, Gaussian processes, to construct a distance modulus μ {sub H} ( z ), which is susceptible to the cosmic curvature parameter Ω{sub k}. In contrary to previous studies, the light-curve-fitting parameters, which account for the distance estimation of SN (μ {sub SN}( z )), are set free to investigate whether Ω {sub k} has a dependence on them. By comparing μ {sub H} ( z ) to μ {sub SN}(z), we put limits on Ω {sub k}. Our results confirm that Ω {sub k} is independent of the SN light-curve parameters. Moreover, we show that the measured Ω {sub k} is in good agreement with zero cosmic curvature, implying that there is no significant deviation from a flat universe at the current observational data level. We also test the influence of different H(z) samples and different Hubble constant H {sub 0} values, finding that different H(z) samples do not have a significant impact on the constraints. However, different H {sub 0} priors can affect the constraints of Ω {sub k} to some degree. The prior of H {sub 0} = 73.24 ± 1.74 km s{sup −1} Mpc{sup −1} gives a value of Ω {sub k}, a little bit above the 1 σ confidence level away from 0, but H{sub 0} = 69.6 ± 0.7 km s{sup −1} Mpc{sup −1} gives it below 1 σ .

  20. A Japanese Stretching Intervention Can Modify Lumbar Lordosis Curvature.

    Science.gov (United States)

    Kadono, Norio; Tsuchiya, Kazushi; Uematsu, Azusa; Kamoshita, Hiroshi; Kiryu, Kazunori; Hortobágyi, Tibor; Suzuki, Shuji

    2017-08-01

    Eighteen healthy male adults were assigned to either an intervention or control group. Isogai dynamic therapy (IDT) is one of Japanese stretching interventions and has been practiced for over 70 years. However, its scientific quantitative evidence remains unestablished. The objective of this study was to determine whether IDT could modify lumbar curvature in healthy young adults compared with stretching exercises used currently in clinical practice. None of previous studies have provided data that conventional stretching interventions could modify spinal curvatures. However, this study provides the first evidence that a specific form of a Japanese stretching intervention can acutely modify the spinal curvatures. We compared the effects of IDT, a Japanese stretching intervention (n=9 males), with a conventional stretching routine (n=9 males) used widely in clinics to modify pelvic tilt and lumbar lordosis (LL) angle. We measured thoracic kyphosis (TK) and LL angles 3 times during erect standing using the Spinal Mouse before and after each intervention. IDT consisted of: (1) hip joint correction, (2) pelvic tilt correction, (3) lumbar alignment correction, and (4) squat exercise stretch. The control group performed hamstring stretches while (1) standing and (2) sitting. IDT increased LL angle to 25.1 degrees (±5.9) from 21.2 degrees (±6.9) (P=0.047) without changing TK angle (pretest: 36.8 degrees [±6.9]; posttest: 36.1 degrees [±6.5]) (P=0.572). The control group showed no changes in TK (P=0.819) and LL angles (P=0.744). IDT can thus be effective for increasing LL angle, hence anterior pelvic tilt. Such modifications could ameliorate low back pain and improve mobility in old adults with an unfavorable pelvic position.

  1. Membrane paradigm

    International Nuclear Information System (INIS)

    Price, R.H.; Thorne, K.S.

    1986-01-01

    The membrane paradigm is a modified frozen star approach to modeling black holes, with particles and fields assuming a complex, static, boundary-layer type structure (membrane) near the event horizon. The membrane has no effects on the present or future evolution of particles and fields above itself. The mathematical representation is a combination of a formalism containing terms for the shear and bulk viscosity, surface pressure, momentum, temperature, entropy, etc., of the horizon and the 3+1 formalism. The latter model considers a family of three-dimensional spacelike hypersurfaces in one-dimensional time. The membrane model considers a magnetic field threading the hole and undergoing torque from the hole rotation. The field is cleaned by the horizon and distributed over the horizon so that ohmic dissipation is minimized. The membrane paradigm is invalid inside the horizon, but is useful for theoretically probing the properties of slowly evolving black holes

  2. Membrane processes

    Science.gov (United States)

    Staszak, Katarzyna

    2017-11-01

    The membrane processes have played important role in the industrial separation process. These technologies can be found in all industrial areas such as food, beverages, metallurgy, pulp and paper, textile, pharmaceutical, automotive, biotechnology and chemical industry, as well as in water treatment for domestic and industrial application. Although these processes are known since twentieth century, there are still many studies that focus on the testing of new membranes' materials and determining of conditions for optimal selectivity, i. e. the optimum transmembrane pressure (TMP) or permeate flux to minimize fouling. Moreover the researchers proposed some calculation methods to predict the membrane processes properties. In this article, the laboratory scale experiments of membrane separation techniques, as well their validation by calculation methods are presented. Because membrane is the "heart" of the process, experimental and computational methods for its characterization are also described.

  3. Curvature fluctuations as progenitors of large scale holes

    International Nuclear Information System (INIS)

    Vittorio, N.; Santangelo, P.; Occhionero, F.

    1984-01-01

    The authors extend previous work to study the formation and evolution of deep holes, under the assumption that they arise from curvature or energy perturbations in the Hubble flow. Their algorithm, which makes use of the spherically symmetric and pressureless Tolman-Bondi solution, can embed a perturbation in any cosmological background. After recalling previous results on the central depth of the hole and its radial dimension, they give here specific examples of density and peculiar velocity profiles, which may have a bearing on whether galaxy formation is a dissipative or dissipationless process. (orig.)

  4. Curvature effect on tearing modes in presence of neoclassical friction

    Energy Technology Data Exchange (ETDEWEB)

    Maget, Patrick; Mellet, Nicolas; Meshcheriakov, Dmytro; Garbet, Xavier [CEA, IRFM, F-13108 Saint Paul-lez-Durance (France); Lütjens, Hinrich [Centre de Physique Théorique, Ecole Polytechnique, CNRS (France)

    2013-11-15

    Neoclassical physics (here associated to the poloidal variation of the magnetic field strength along field lines in a tokamak) is well known for driving self-generated plasma current and nonlinear magnetic islands associated to it in high performance, ITER relevant plasma discharges. It is demonstrated that the neoclassical friction between a magnetic perturbation and plasma flow already impacts magnetic islands in the linear regime, by inducing a weakening of curvature stabilization for tearing modes. This conclusion holds in particular for regimes where convection is influencing the pressure dynamics, as shown using a simple analytical model and confirmed in full Magneto-Hydro-Dynamics simulations.

  5. The natural selection of metabolism explains curvature in allometric scaling

    OpenAIRE

    Witting, Lars

    2016-01-01

    I simulate the evolution of metabolism and mass to explain the curvature in the metabolic allometry for placental and marsupial mammals. I assume that the release of inter-specific competition by the extinction of dinosaurs 65 million years ago made it possible for each clade to diversity into a multitude of species across a wide range of niches. The natural selection of metabolism and mass was then fitted to explain the maximum observed body masses over time, as well as the current inter-spe...

  6. The evolution of space curves by curvature and torsion

    International Nuclear Information System (INIS)

    Richardson, G; King, J R

    2002-01-01

    We apply Lie group based similarity methods to the study of a new, and widely relevant, class of objects, namely motions of a space curve. In particular, we consider the motion of a curve evolving with a curvature κ and torsion τ dependent velocity law. We systematically derive the Lie point symmetries of all such laws of motion and use these to catalogue all their possible similarity reductions. This calculation reveals special classes of law with high degrees of symmetry (and a correspondingly large number of similarity reductions). Of particular note is one class which is invariant under general linear transformations in space. This has potential applications in pattern and signal recognition

  7. Rigid particle revisited: Extrinsic curvature yields the Dirac equation

    Energy Technology Data Exchange (ETDEWEB)

    Deriglazov, Alexei, E-mail: alexei.deriglazov@ufjf.edu.br [Depto. de Matemática, ICE, Universidade Federal de Juiz de Fora, MG (Brazil); Laboratory of Mathematical Physics, Tomsk Polytechnic University, 634050 Tomsk, Lenin Ave. 30 (Russian Federation); Nersessian, Armen, E-mail: arnerses@ysu.am [Yerevan State University, 1 Alex Manoogian St., Yerevan 0025 (Armenia); Laboratory of Mathematical Physics, Tomsk Polytechnic University, 634050 Tomsk, Lenin Ave. 30 (Russian Federation)

    2014-03-01

    We reexamine the model of relativistic particle with higher-derivative linear term on the first extrinsic curvature (rigidity). The passage from classical to quantum theory requires a number of rather unexpected steps which we report here. We found that, contrary to common opinion, quantization of the model in terms of so(3.2)-algebra yields massive Dirac equation. -- Highlights: •New way of canonical quantization of relativistic rigid particle is proposed. •Quantization made in terms of so(3.2) angular momentum algebra. •Quantization yields massive Dirac equation.

  8. Field equations for gravity quadratic in the curvature

    International Nuclear Information System (INIS)

    Rose, B.

    1992-01-01

    Vacuum field equations for gravity are studied having their origin in a Lagrangian quadratic in the curvature. The motivation for this choice of the Lagrangian-namely the treating of gravity in a strict analogy to gauge theories of Yang-Mills type-is criticized, especially the implied view of connections as gauge potentials with no dynamical relation to the metric. The correct field equations with respect to variation of the connections and the metric independently are given. We deduce field equations which differs from previous ones by variation of the metric, the torsion, and the nonmetricity from which the connections are built. 6 refs

  9. 2008 ULTRASONIC BENCHMARK STUDIES OF INTERFACE CURVATURE--A SUMMARY

    International Nuclear Information System (INIS)

    Schmerr, L. W.; Huang, R.; Raillon, R.; Mahaut, S.; Leymarie, N.; Lonne, S.; Song, S.-J.; Kim, H.-J.; Spies, M.; Lupien, V.

    2009-01-01

    In the 2008 QNDE ultrasonic benchmark session researchers from five different institutions around the world examined the influence that the curvature of a cylindrical fluid-solid interface has on the measured NDE immersion pulse-echo response of a flat-bottom hole (FBH) reflector. This was a repeat of a study conducted in the 2007 benchmark to try to determine the sources of differences seen in 2007 between model-based predictions and experiments. Here, we will summarize the results obtained in 2008 and analyze the model-based results and the experiments.

  10. Understanding Detergent Effects on Lipid Membranes: A Model Study of Lysolipids

    DEFF Research Database (Denmark)

    Henriksen, Jonas Rosager; Andresen, Thomas Lars; Feldborg, Lise Nørkjær

    2010-01-01

    Lysolipids and fatty acids are the natural products formed by the hydrolysis of phospholipids. Lysolipids and fatty acids form micelles in solution and acts as detergents in the presence of lipid membranes. In this study, we investigate the detergent strength of a homologous series of lyso......-chain mismatch between LPC and POPC determines the magnitude of the membrane mechanical perturbation per LPC molecule in the membrane. Finally, the three-stage model describing detergent membrane interaction has been extended by a parameter D-MCI, which governs the membrane curvature stability in the detergent...

  11. Numerical and Theoretical Investigations Concerning the Continuous-Surface-Curvature Effect in Compressor Blades

    Directory of Open Access Journals (Sweden)

    Yin Song

    2014-12-01

    Full Text Available Though the importance of curvature continuity on compressor blade performances has been realized, there are two major questions that need to be solved, i.e., the respective effects of curvature continuity at the leading-edge blend point and the main surface, and the contradiction between the traditional theory and experimental observations in the effect of those novel leading-edge shapes with smaller curvature discontinuity and sharper nose. In this paper, an optimization method to design continuous-curvature blade profiles which deviate little from datum blades is proposed, and numerical and theoretical analysis is carried out to investigate the continuous-curvature effect on blade performances. The results show that the curvature continuity at the leading-edge blend point helps to eliminate the separation bubble, thus improving the blade performance. The main-surface curvature continuity is also beneficial, although its effects are much smaller than those of the blend-point curvature continuity. Furthermore, it is observed that there exist two factors controlling the leading-edge spike, i.e., the curvature discontinuity at the blend point which dominates at small incidences, and the nose curvature which dominates at large incidences. To the authors’ knowledge, such mechanisms have not been reported before, and they can help to solve the sharp-leading-edge paradox.

  12. Effect of Plate Curvature on Blast Response of Structural Steel Plates

    Science.gov (United States)

    Veeredhi, Lakshmi Shireen Banu; Ramana Rao, N. V.; Veeredhi, Vasudeva Rao

    2018-04-01

    In the present work an attempt is made, through simulation studies, to determine the effect of plate curvature on the blast response of a door structure made of ASTM A515 grade 50 steel plates. A door structure with dimensions of 5.142 m × 2.56 m × 10 mm having six different radii of curvatures is analyzed which is subjected to blast load. The radii of curvature investigated are infinity (flat plate), 16.63, 10.81, 8.26, 6.61 and 5.56 m. In the present study, a stand-off distance of 11 m is considered for all the cases. Results showed that the door structure with smallest radius of curvature experienced least plastic deformation and yielding when compared to a door with larger radius of curvature with same projected area. From the present Investigation, it is observed that, as the radius of curvature of the plate increases, the deformation mode gradually shifts from indentation mode to flexural mode. The plates with infinity and 16.63 m radius of curvature have undergone flexural mode of deformation and plates with 6.61 and 5.56 m radius of curvature undergo indentation mode of deformation. Whereas, mixed mode of deformation that consists of both flexural and indentation mode of deformations are seen in the plates with radius of curvature 10.81 and 8.26 m. As the radius of curvature of the plate decreases the ability of the plate to mitigate the effect the blast loads increased. It is observed that the plate with smaller radius of curvature deflects most of the blast energy and results in least indentation mode of deformation. The most significant observation made in the present investigation is that the strain energy absorbed by the steel plate gets reduced to 1/3 rd when the radius of curvature is approximately equal to the stand-off distance which could be the critical radius of curvature.

  13. Compatibility of Mating Preferences

    OpenAIRE

    Bingol, Haluk O.; Basar, Omer

    2016-01-01

    Human mating is a complex phenomenon. Although men and women have different preferences in mate selection, there should be compatibility in these preferences since human mating requires agreement of both parties. We investigate how compatible the mating preferences of men and women are in a given property such as age, height, education and income. We use dataset of a large online dating site (N = 44, 255 users). (i) Our findings are based on the "actual behavior" of users trying to find a dat...

  14. Mechanism of Shiga Toxin Clustering on Membranes

    DEFF Research Database (Denmark)

    Pezeshkian, Weria; Gao, Haifei; Arumugam, Senthil

    2017-01-01

    between them. The precise mechanism by which this clustering occurs remains poorly defined. Here, we used vesicle and cell systems and computer simulations to show that line tension due to curvature, height, or compositional mismatch, and lipid or solvent depletion cannot drive the clustering of Shiga...... toxin molecules. By contrast, in coarse-grained computer simulations, a correlation was found between clustering and toxin nanoparticle-driven suppression of membrane fluctuations, and experimentally we observed that clustering required the toxin molecules to be tightly bound to the membrane surface...... molecules (several nanometers), and persist even beyond. This force is predicted to operate between manufactured nanoparticles providing they are sufficiently rigid and tightly bound to the plasma membrane, thereby suggesting a route for the targeting of nanoparticles to cells for biomedical applications....

  15. The Physical Properties of Ceramides in Membranes.

    Science.gov (United States)

    Alonso, Alicia; Goñi, Félix M

    2018-05-20

    Ceramides are sphingolipids containing a sphingosine or a related base, to which a fatty acid is linked through an amide bond. When incorporated into a lipid bilayer, ceramides exhibit a number of properties not shared by almost any other membrane lipid: Ceramides ( a) are extremely hydrophobic and thus cannot exist in suspension in aqueous media; ( b) increase the molecular order (rigidity) of phospholipids in membranes; ( c) give rise to lateral phase separation and domain formation in phospholipid bilayers; ( d) possess a marked intrinsic negative curvature that facilitates formation of inverted hexagonal phases; ( e) make bilayers and cell membranes permeable to small and large (i.e., protein-size) solutes; and ( f) promote transmembrane (flip-flop) lipid motion. Unfortunately, there is hardly any link between the physical studies reviewed here and the mass of biological and clinical studies on the effects of ceramides in health and disease.

  16. Memory for curvature of objects: haptic touch vs. vision.

    Science.gov (United States)

    Ittyerah, Miriam; Marks, Lawrence E

    2007-11-01

    The present study examined the role of vision and haptics in memory for stimulus objects that vary along the dimension of curvature. Experiment 1 measured haptic-haptic (T-T) and haptic-visual (T-V) discrimination of curvature in a short-term memory paradigm, using 30-second retention intervals containing five different interpolated tasks. Results showed poorest performance when the interpolated tasks required spatial processing or movement, thereby suggesting that haptic information about shape is encoded in a spatial-motor representation. Experiment 2 compared visual-visual (V-V) and visual-haptic (V-T) short-term memory, again using 30-second delay intervals. The results of the ANOVA failed to show a significant effect of intervening activity. Intra-modal visual performance and cross-modal performance were similar. Comparing the four modality conditions (inter-modal V-T, T-V; intra-modal V-V, T-T, by combining the data of Experiments 1 and 2), in a global analysis, showed a reliable interaction between intervening activity and experiment (modality). Although there appears to be a general tendency for spatial and movement activities to exert the most deleterious effects overall, the patterns are not identical when the initial stimulus is encoded haptically (Experiment 1) and visually (Experiment 2).

  17. Characterizing Suspension Plasma Spray Coating Formation Dynamics through Curvature Measurements

    Science.gov (United States)

    Chidambaram Seshadri, Ramachandran; Dwivedi, Gopal; Viswanathan, Vaishak; Sampath, Sanjay

    2016-12-01

    Suspension plasma spraying (SPS) enables the production of variety of microstructures with unique mechanical and thermal properties. In SPS, a liquid carrier (ethanol/water) is used to transport the sub-micrometric feedstock into the plasma jet. Considering complex deposition dynamics of SPS technique, there is a need to better understand the relationships among spray conditions, ensuing particle behavior, deposition stress evolution and resultant properties. In this study, submicron yttria-stabilized zirconia particles suspended in ethanol were sprayed using a cascaded arc plasma torch. The stresses generated during the deposition of the layers (termed evolving stress) were monitored via the change in curvature of the substrate measured using an in situ measurement apparatus. Depending on the deposition conditions, coating microstructures ranged from feathery porous to dense/cracked deposits. The evolving stresses and modulus were correlated with the observed microstructures and visualized via process maps. Post-deposition bi-layer curvature measurement via low temperature thermal cycling was carried out to quantify the thermo-elastic response of different coatings. Lastly, preliminary data on furnace cycle durability of different coating microstructures were evaluated. This integrated study involving in situ diagnostics and ex situ characterization along with process maps provides a framework to describe coating formation mechanisms, process parametrics and microstructure description.

  18. Constant curvature algebras and higher spin action generating functions

    International Nuclear Information System (INIS)

    Hallowell, K.; Waldron, A.

    2005-01-01

    The algebra of differential geometry operations on symmetric tensors over constant curvature manifolds forms a novel deformation of the sl(2,R)-bar R 2 Lie algebra. We present a simple calculus for calculations in its universal enveloping algebra. As an application, we derive generating functions for the actions and gauge invariances of massive, partially massless and massless (for both Bose and Fermi statistics) higher spins on constant curvature backgrounds. These are formulated in terms of a minimal set of covariant, unconstrained, fields rather than towers of auxiliary fields. Partially massless gauge transformations are shown to arise as degeneracies of the flat, massless gauge transformation in one dimension higher. Moreover, our results and calculus offer a considerable simplification over existing techniques for handling higher spins. In particular, we show how theories of arbitrary spin in dimension d can be rewritten in terms of a single scalar field in dimension 2d where the d additional dimensions correspond to coordinate differentials. We also develop an analogous framework for spinor-tensor fields in terms of the corresponding superalgebra

  19. Limited capacity for contour curvature in iconic memory.

    Science.gov (United States)

    Sakai, Koji

    2006-06-01

    We measured the difference threshold for contour curvature in iconic memory by using the cued discrimination method. The study stimulus consisting of 2 to 6 curved contours was briefly presented in the fovea, followed by two lines as cues. Subjects discriminated the curvature of two cued curves. The cue delays were 0 msec. and 300 msec. in Exps. 1 and 2, respectively, and 50 msec. before the study offset in Exp. 3. Analysis of data from Exps. 1 and 2 showed that the Weber fraction rose monotonically with the increase in set size. Clear set-size effects indicate that iconic memory has a limited capacity. Moreover, clear set-size effect in Exp. 3 indicates that perception itself has a limited capacity. Larger set-size effects in Exp. 1 than in Exp. 3 suggest that iconic memory after perceptual process has limited capacity. These properties of iconic memory at threshold level are contradictory to the traditional view that iconic memory has a high capacity both at suprathreshold and categorical levels.

  20. Nonlinear quantum gravity on the constant mean curvature foliation

    International Nuclear Information System (INIS)

    Wang, Charles H-T

    2005-01-01

    A new approach to quantum gravity is presented based on a nonlinear quantization scheme for canonical field theories with an implicitly defined Hamiltonian. The constant mean curvature foliation is employed to eliminate the momentum constraints in canonical general relativity. It is, however, argued that the Hamiltonian constraint may be advantageously retained in the reduced classical system to be quantized. This permits the Hamiltonian constraint equation to be consistently turned into an expectation value equation on quantization that describes the scale factor on each spatial hypersurface characterized by a constant mean exterior curvature. This expectation value equation augments the dynamical quantum evolution of the unconstrained conformal three-geometry with a transverse traceless momentum tensor density. The resulting quantum theory is inherently nonlinear. Nonetheless, it is unitary and free from a nonlocal and implicit description of the Hamiltonian operator. Finally, by imposing additional homogeneity symmetries, a broad class of Bianchi cosmological models are analysed as nonlinear quantum minisuperspaces in the context of the proposed theory

  1. Primordial membranes

    DEFF Research Database (Denmark)

    Hanczyc, Martin M; Monnard, Pierre-Alain

    2017-01-01

    Cellular membranes, which are self-assembled bilayer structures mainly composed of lipids, proteins and conjugated polysaccharides, are the defining feature of cell physiology. It is likely that the complexity of contemporary cells was preceded by simpler chemical systems or protocells during...... the various evolutionary stages that led from inanimate to living matter. It is also likely that primitive membranes played a similar role in protocell 'physiology'. The composition of such ancestral membranes has been proposed as mixtures of single hydrocarbon chain amphiphiles, which are simpler versions...

  2. Observational constraints on dark energy and cosmic curvature

    International Nuclear Information System (INIS)

    Wang Yun; Mukherjee, Pia

    2007-01-01

    Current observational bounds on dark energy depend on our assumptions about the curvature of the universe. We present a simple and efficient method for incorporating constraints from cosmic microwave background (CMB) anisotropy data and use it to derive constraints on cosmic curvature and dark energy density as a free function of cosmic time using current CMB, Type Ia supernova (SN Ia), and baryon acoustic oscillation data. We show that there are two CMB shift parameters, R≡√(Ω m H 0 2 )r(z CMB ) (the scaled distance to recombination) and l a ≡πr(z CMB )/r s (z CMB ) (the angular scale of the sound horizon at recombination), with measured values that are nearly uncorrelated with each other. Allowing nonzero cosmic curvature, the three-year WMAP (Wilkinson Microwave Anisotropy Probe) data give R=1.71±0.03, l a =302.5±1.2, and Ω b h 2 =0.02173±0.00082, independent of the dark energy model. The corresponding bounds for a flat universe are R=1.70±0.03, l a =302.2±1.2, and Ω b h 2 =0.022±0.00082. We give the covariance matrix of (R,l a ,Ω b h 2 ) from the three-year WMAP data. We find that (R,l a ,Ω b h 2 ) provide an efficient and intuitive summary of CMB data as far as dark energy constraints are concerned. Assuming the Hubble Space Telescope (HST) prior of H 0 =72±8 (km/s) Mpc -1 , using 182 SNe Ia (from the HST/GOODS program, the first year Supernova Legacy Survey, and nearby SN Ia surveys), (R,l a ,Ω b h 2 ) from WMAP three-year data, and SDSS (Sloan Digital Sky Survey) measurement of the baryon acoustic oscillation scale, we find that dark energy density is consistent with a constant in cosmic time, with marginal deviations from a cosmological constant that may reflect current systematic uncertainties or true evolution in dark energy. A flat universe is allowed by current data: Ω k =-0.006 -0.012-0.025 +0.013+0.025 for assuming that the dark energy equation of state w X (z) is constant, and Ω k =-0.002 -0.018-0.032 +0.018+0.041 for w X (z

  3. Effect of nano-scale curvature on the intrinsic blood coagulation system

    Science.gov (United States)

    Kushida, Takashi; Saha, Krishnendu; Subramani, Chandramouleeswaran; Nandwana, Vikas; Rotello, Vincent M.

    2014-11-01

    The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation `silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation.The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation `silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation. Electronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c

  4. Membranous nephropathy

    Science.gov (United States)

    ... skin-lightening creams Systemic lupus erythematosus , rheumatoid arthritis, Graves disease, and other autoimmune disorders The disorder occurs at ... diagnosis. The following tests can help determine the cause of membranous nephropathy: Antinuclear antibodies test Anti-double- ...

  5. Fabrication of complex free-standing nanostructures with concave and convex curvature via the layer-by-layer approach.

    Science.gov (United States)

    Raoufi, Mohammad; Schönherr, Holger

    2014-02-18

    We report on the fabrication of unprecedented free-standing complex polymeric nanoobjects, which possess both concave and convex curvatures, by exploiting the layer-by-layer (LBL) deposition of polyelectrolytes. In a combined top-down/bottom-up replication approach pore diameter-modulated anodic aluminum oxide (AAO) templates, fabricated by temperature modulation hard anodization (TMHA), were replicated with multilayers of poly(styrene sulfonate) (PSS) and poly(allylamine hydrochloride) (PAH) to yield open nanotubes with diameters in the wide and narrow segments of 210 and 150 nm, respectively. To obtain stable pore diameter-modulated nanopores, which possess segment lengths between 1 and 5 μm and 5 and 10 μm in the narrow and wide pore portion, respectively, conventional hard anodization of aluminum was followed by a subsequent temperature-modulated anodization. After removing the backside aluminum electrode, silanizing the aluminum oxide, and passivating the exposed membrane surface with a thin layer of gold, PSS and PAH were deposited alternatingly to yield LBL multilayers. For optimized LBL multilayer thicknesses and compactness, established in separate experiments on silicon substrates and nanoporous AAO with straight pores, free-standing polymeric nanoobjects with concave and convex curvatures, were obtained. These were stable for wall thickness to pore diameter ratios of ≥0.08.

  6. Discrimination of curvature from motion during smooth pursuit eye movements and fixation.

    Science.gov (United States)

    Ross, Nicholas M; Goettker, Alexander; Schütz, Alexander C; Braun, Doris I; Gegenfurtner, Karl R

    2017-09-01

    Smooth pursuit and motion perception have mainly been investigated with stimuli moving along linear trajectories. Here we studied the quality of pursuit movements to curved motion trajectories in human observers and examined whether the pursuit responses would be sensitive enough to discriminate various degrees of curvature. In a two-interval forced-choice task subjects pursued a Gaussian blob moving along a curved trajectory and then indicated in which interval the curve was flatter. We also measured discrimination thresholds for the same curvatures during fixation. Motion curvature had some specific effects on smooth pursuit properties: trajectories with larger amounts of curvature elicited lower open-loop acceleration, lower pursuit gain, and larger catch-up saccades compared with less curved trajectories. Initially, target motion curvatures were underestimated; however, ∼300 ms after pursuit onset pursuit responses closely matched the actual curved trajectory. We calculated perceptual thresholds for curvature discrimination, which were on the order of 1.5 degrees of visual angle (°) for a 7.9° curvature standard. Oculometric sensitivity to curvature discrimination based on the whole pursuit trajectory was quite similar to perceptual performance. Oculometric thresholds based on smaller time windows were higher. Thus smooth pursuit can quite accurately follow moving targets with curved trajectories, but temporal integration over longer periods is necessary to reach perceptual thresholds for curvature discrimination. NEW & NOTEWORTHY Even though motion trajectories in the real world are frequently curved, most studies of smooth pursuit and motion perception have investigated linear motion. We show that pursuit initially underestimates the curvature of target motion and is able to reproduce the target curvature ∼300 ms after pursuit onset. Temporal integration of target motion over longer periods is necessary for pursuit to reach the level of precision found

  7. Eye tracking social preferences

    NARCIS (Netherlands)

    Jiang, Ting; Potters, Jan; Funaki, Yukihiko

    We hypothesize that if people are motivated by a particular social preference, then choosing in accordance with this preference will lead to an identifiable pattern of eye movements. We track eye movements while subjects make choices in simple three-person distribution experiments. We characterize

  8. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  9. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    2000-01-01

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  10. Measuring Normative Risk Preferences

    NARCIS (Netherlands)

    G.A.G. Alserda (Gosse)

    2017-01-01

    textabstractThe results of eliciting risk preferences depend on the elicitation method. Different methods of measuring the same variable tend to produce different results. This raises the question whether normative risk preferences can be elicited at all. Using two types of manipulation, I assess

  11. Measurement of curvature and twist of a deformed object using digital holography

    International Nuclear Information System (INIS)

    Chen Wen; Quan Chenggen; Cho Jui Tay

    2008-01-01

    Measurement of curvature and twist is an important aspect in the study of object deformation. In recent years, several methods have been proposed to determine curvature and twist of a deformed object using digital shearography. Here we propose a novel method to determine the curvature and twist of a deformed object using digital holography and a complex phasor. A sine/cosine transformation method and two-dimensional short time Fourier transform are proposed subsequently to process the wrapped phase maps. It is shown that high-quality phase maps corresponding to curvature and twist can be obtained. An experiment is conducted to demonstrate the validity of the proposed method

  12. Intensity-Curvature Measurement Approaches for the Diagnosis of Magnetic Resonance Imaging Brain Tumors

    Directory of Open Access Journals (Sweden)

    Carlo Ciulla

    2015-11-01

    Full Text Available This research presents signal-image post-processing techniques called Intensity-Curvature Measurement Approaches with application to the diagnosis of human brain tumors detected through Magnetic Resonance Imaging (MRI. Post-processing of the MRI of the human brain encompasses the following model functions: (i bivariate cubic polynomial, (ii bivariate cubic Lagrange polynomial, (iii monovariate sinc, and (iv bivariate linear. The following Intensity-Curvature Measurement Approaches were used: (i classic-curvature, (ii signal resilient to interpolation, (iii intensity-curvature measure and (iv intensity-curvature functional. The results revealed that the classic-curvature, the signal resilient to interpolation and the intensity-curvature functional are able to add additional information useful to the diagnosis carried out with MRI. The contribution to the MRI diagnosis of our study are: (i the enhanced gray level scale of the tumor mass and the well-behaved representation of the tumor provided through the signal resilient to interpolation, and (ii the visually perceptible third dimension perpendicular to the image plane provided through the classic-curvature and the intensity-curvature functional.

  13. A major QTL controls susceptibility to spinal curvature in the curveback guppy

    Directory of Open Access Journals (Sweden)

    Dreyer Christine

    2011-01-01

    Full Text Available Abstract Background Understanding the genetic basis of heritable spinal curvature would benefit medicine and aquaculture. Heritable spinal curvature among otherwise healthy children (i.e. Idiopathic Scoliosis and Scheuermann kyphosis accounts for more than 80% of all spinal curvatures and imposes a substantial healthcare cost through bracing, hospitalizations, surgery, and chronic back pain. In aquaculture, the prevalence of heritable spinal curvature can reach as high as 80% of a stock, and thus imposes a substantial cost through production losses. The genetic basis of heritable spinal curvature is unknown and so the objective of this work is to identify quantitative trait loci (QTL affecting heritable spinal curvature in the curveback guppy. Prior work with curveback has demonstrated phenotypic parallels to human idiopathic-type scoliosis, suggesting shared biological pathways for the deformity. Results A major effect QTL that acts in a recessive manner and accounts for curve susceptibility was detected in an initial mapping cross on LG 14. In a second cross, we confirmed this susceptibility locus and fine mapped it to a 5 cM region that explains 82.6% of the total phenotypic variance. Conclusions We identify a major QTL that controls susceptibility to curvature. This locus contains over 100 genes, including MTNR1B, a candidate gene for human idiopathic scoliosis. The identification of genes associated with heritable spinal curvature in the curveback guppy has the potential to elucidate the biological basis of spinal curvature among humans and economically important teleosts.

  14. Computational methods for investigation of surface curvature effects on airfoil boundary layer behavior

    Directory of Open Access Journals (Sweden)

    Xiang Shen

    2017-03-01

    Full Text Available This article presents computational algorithms for the design, analysis, and optimization of airfoil aerodynamic performance. The prescribed surface curvature distribution blade design (CIRCLE method is applied to a symmetrical airfoil NACA0012 and a non-symmetrical airfoil E387 to remove their surface curvature and slope-of-curvature discontinuities. Computational fluid dynamics analysis is used to investigate the effects of curvature distribution on aerodynamic performance of the original and modified airfoils. An inviscid–viscid interaction scheme is introduced to predict the positions of laminar separation bubbles. The results are compared with experimental data obtained from tests on the original airfoil geometry. The computed aerodynamic advantages of the modified airfoils are analyzed in different operating conditions. The leading edge singularity of NACA0012 is removed and it is shown that the surface curvature discontinuity affects aerodynamic performance near the stalling angle of attack. The discontinuous slope-of-curvature distribution of E387 results in a larger laminar separation bubble at lower angles of attack and lower Reynolds numbers. It also affects the inherent performance of the airfoil at higher Reynolds numbers. It is shown that at relatively high angles of attack, a continuous slope-of-curvature distribution reduces the skin friction by suppressing both laminar and turbulent separation, and by delaying laminar-turbulent transition. It is concluded that the surface curvature distribution has significant effects on the boundary layer behavior and consequently an improved curvature distribution will lead to higher aerodynamic efficiency.

  15. Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins.

    Science.gov (United States)

    Suetsugu, Shiro; Kurisu, Shusaku; Takenawa, Tadaomi

    2014-10-01

    All cellular compartments are separated from the external environment by a membrane, which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits, caveolae, filopodia, lamellipodia, podosomes, and other intracellular membrane systems, are molded into their specific submicron-scale shapes through various mechanisms. Cells construct their micro-structures on plasma membrane and execute vital functions for life, such as cell migration, cell division, endocytosis, exocytosis, and cytoskeletal regulation. The plasma membrane, rich in anionic phospholipids, utilizes the electrostatic nature of the lipids, specifically the phosphoinositides, to form interactions with cytosolic proteins. These cytosolic proteins have three modes of interaction: 1) electrostatic interaction through unstructured polycationic regions, 2) through structured phosphoinositide-specific binding domains, and 3) through structured domains that bind the membrane without specificity for particular phospholipid. Among the structured domains, there are several that have membrane-deforming activity, which is essential for the formation of concave or convex membrane curvature. These domains include the amphipathic helix, which deforms the membrane by hemi-insertion of the helix with both hydrophobic and electrostatic interactions, and/or the BAR domain superfamily, known to use their positively charged, curved structural surface to deform membranes. Below the membrane, actin filaments support the micro-structures through interactions with several BAR proteins as well as other scaffold proteins, resulting in outward and inward membrane micro-structure formation. Here, we describe the characteristics of phospholipids, and the mechanisms utilized by phosphoinositides to regulate cellular events. We then summarize the precise mechanisms underlying the construction of membrane micro-structures and their involvements in physiological and pathological processes. Copyright © 2014 the

  16. Spectral combination of spherical gravitational curvature boundary-value problems

    Science.gov (United States)

    PitoÅák, Martin; Eshagh, Mehdi; Šprlák, Michal; Tenzer, Robert; Novák, Pavel

    2018-04-01

    Four solutions of the spherical gravitational curvature boundary-value problems can be exploited for the determination of the Earth's gravitational potential. In this article we discuss the combination of simulated satellite gravitational curvatures, i.e., components of the third-order gravitational tensor, by merging these solutions using the spectral combination method. For this purpose, integral estimators of biased- and unbiased-types are derived. In numerical studies, we investigate the performance of the developed mathematical models for the gravitational field modelling in the area of Central Europe based on simulated satellite measurements. Firstly, we verify the correctness of the integral estimators for the spectral downward continuation by a closed-loop test. Estimated errors of the combined solution are about eight orders smaller than those from the individual solutions. Secondly, we perform a numerical experiment by considering the Gaussian noise with the standard deviation of 6.5× 10-17 m-1s-2 in the input data at the satellite altitude of 250 km above the mean Earth sphere. This value of standard deviation is equivalent to a signal-to-noise ratio of 10. Superior results with respect to the global geopotential model TIM-r5 are obtained by the spectral downward continuation of the vertical-vertical-vertical component with the standard deviation of 2.104 m2s-2, but the root mean square error is the largest and reaches 9.734 m2s-2. Using the spectral combination of all gravitational curvatures the root mean square error is more than 400 times smaller but the standard deviation reaches 17.234 m2s-2. The combination of more components decreases the root mean square error of the corresponding solutions while the standard deviations of the combined solutions do not improve as compared to the solution from the vertical-vertical-vertical component. The presented method represents a weight mean in the spectral domain that minimizes the root mean square error

  17. Mechanical collapse of confined fluid membrane vesicles.

    Science.gov (United States)

    Rim, Jee E; Purohit, Prashant K; Klug, William S

    2014-11-01

    Compact cylindrical and spherical invaginations are common structural motifs found in cellular and developmental biology. To understand the basic physical mechanisms that produce and maintain such structures, we present here a simple model of vesicles in confinement, in which mechanical equilibrium configurations are computed by energy minimization, balancing the effects of curvature elasticity, contact of the membrane with itself and the confining geometry, and adhesion. For cylindrical confinement, the shape equations are solved both analytically and numerically by finite element analysis. For spherical confinement, axisymmetric configurations are obtained numerically. We find that the geometry of invaginations is controlled by a dimensionless ratio of the adhesion strength to the bending energy of an equal area spherical vesicle. Larger adhesion produces more concentrated curvatures, which are mainly localized to the "neck" region where the invagination breaks away from its confining container. Under spherical confinement, axisymmetric invaginations are approximately spherical. For extreme confinement, multiple invaginations may form, bifurcating along multiple equilibrium branches. The results of the model are useful for understanding the physical mechanisms controlling the structure of lipid membranes of cells and their organelles, and developing tissue membranes.

  18. Surface Curvature in Island Groups and Discontinuous Cratonic Structures

    Science.gov (United States)

    McDowell, M. S.

    2002-05-01

    The Canadian Archipelago includes eight major islands and a host of smaller ones. They are separated by water bodies, of varying widths attributable to glacial activity and ocean currents. Land form varies from relatively rugged mountains (~2000 m) in eastern, glacial, islands, to low lying western, similar to the continental topography adjacent. The Arctic region is thought to have been low average elevation before the Pleistocene. To a picture puzzler, it all looks like it fit together. Experimentally cutting apart the islands from large scale maps shows that the rough edges match fairly well. However, when those independent pieces are sutured together, without restraint, as in free air, the fit is far better. Far more importantly, they consistently form a noticeably concave surface. This tendency is not at all apparent in flat surface or computer screen manipulation; the pieces need to be "hand joined" or on a molded surface to allow the assembly to freely form as it will. Fitting together the coastlines above 60 \\deg north, from 120 \\deg west to 45 \\deg east, and comparing the resulting contracted area to the original, obtains an 8 percent area reduction. The curvature "humps" a trial planar section of 15 cms by 1.6 cm, a substantial difference in the radius of curvature. If you rashly suggest applying that formula globally, the resulting sphere would have a surface area of 4.7 x108,(down from 5 x108), and therefore radius of 6117 km, down from 6400, which is a rather preposterous conclusion. As nobody would believe it, I tested the idea elsewhere. The Huronian succession of six named cratons is adjacent on the south. I cut this map apart, too, and fit it together, once again getting a curvature, this time more pronounced. I am trying it with the Indonesian Archipelago, although this area has volcanic complications, and with Precambrian Basins in western Australia and Nimibia, Africa. Indications are - an essentially similar pattern of fit, but non uniform

  19. Converting entropy to curvature perturbations after a cosmic bounce

    Energy Technology Data Exchange (ETDEWEB)

    Fertig, Angelika; Lehners, Jean-Luc; Mallwitz, Enno; Wilson-Ewing, Edward [Max Planck Institute for Gravitational Physics, Albert Einstein Institute,14476 Potsdam-Golm (Germany)

    2016-10-04

    We study two-field bouncing cosmologies in which primordial perturbations are created in either an ekpyrotic or a matter-dominated contraction phase. We use a non-singular ghost condensate bounce model to follow the perturbations through the bounce into the expanding phase of the universe. In contrast to the adiabatic perturbations, which on large scales are conserved across the bounce, entropy perturbations can grow significantly during the bounce phase. If they are converted into adiabatic/curvature perturbations after the bounce, they typically form the dominant contribution to the observed temperature fluctuations in the microwave background, which can have several beneficial implications. For ekpyrotic models, this mechanism loosens the constraints on the amplitude of the ekpyrotic potential while naturally suppressing the intrinsic amount of non-Gaussianity. For matter bounce models, the mechanism amplifies the scalar perturbations compared to the associated primordial gravitational waves.

  20. Observational constraints on the primordial curvature power spectrum

    Science.gov (United States)

    Emami, Razieh; Smoot, George F.

    2018-01-01

    CMB temperature fluctuation observations provide a precise measurement of the primordial power spectrum on large scales, corresponding to wavenumbers 10‑3 Mpc‑1 lesssim k lesssim 0.1 Mpc‑1, [1-7, 11]. Luminous red galaxies and galaxy clusters probe the matter power spectrum on overlapping scales (0.02 Mpc‑1 lesssim k lesssim 0.7 Mpc‑1 [10, 12-20]), while the Lyman-alpha forest reaches slightly smaller scales (0.3 Mpc‑1 lesssim k lesssim 3 Mpc‑1 [22]). These observations indicate that the primordial power spectrum is nearly scale-invariant with an amplitude close to 2 × 10‑9, [5, 23-28]. These observations strongly support Inflation and motivate us to obtain observations and constraints reaching to smaller scales on the primordial curvature power spectrum and by implication on Inflation. We are able to obtain limits to much higher values of k lesssim 105 Mpc‑1 and with less sensitivity even higher k lesssim 1019‑ 1023 Mpc‑1 using limits from CMB spectral distortions and other limits on ultracompact minihalo objects (UCMHs) and Primordial Black Holes (PBHs). PBHs are one of the known candidates for the Dark Matter (DM). Due to their very early formation, they could give us valuable information about the primordial curvature perturbations. These are complementary to other cosmological bounds on the amplitude of the primordial fluctuations. In this paper, we revisit and collect all the published constraints on both PBHs and UCMHs. We show that unless one uses the CMB spectral distortion, PBHs give us a very relaxed bounds on the primordial curvature perturbations. UCMHs, on the other hand, are very informative over a reasonable k range (3 lesssim k lesssim 106 Mpc‑1) and lead to significant upper-bounds on the curvature spectrum. We review the conditions under which the tighter constraints on the UCMHs could imply extremely strong bounds on the fraction of DM that could be PBHs in reasonable models. Failure to satisfy these conditions would

  1. Reachability by paths of bounded curvature in a convex polygon

    KAUST Repository

    Ahn, Heekap; Cheong, Otfried; Matoušek, Jiřǐ; Vigneron, Antoine E.

    2012-01-01

    Let B be a point robot moving in the plane, whose path is constrained to forward motions with curvature at most 1, and let P be a convex polygon with n vertices. Given a starting configuration (a location and a direction of travel) for B inside P, we characterize the region of all points of P that can be reached by B, and show that it has complexity O(n). We give an O(n2) time algorithm to compute this region. We show that a point is reachable only if it can be reached by a path of type CCSCS, where C denotes a unit circle arc and S denotes a line segment. © 2011 Elsevier B.V.

  2. Constraints on amplitudes of curvature perturbations from primordial black holes

    International Nuclear Information System (INIS)

    Bugaev, Edgar; Klimai, Peter

    2009-01-01

    We calculate the primordial black hole (PBH) mass spectrum produced from a collapse of the primordial density fluctuations in the early Universe using, as an input, several theoretical models giving the curvature perturbation power spectra P R (k) with large (∼10 -2 -10 -1 ) values at some scale of comoving wave numbers k. In the calculation we take into account the explicit dependence of gravitational (Bardeen) potential on time. Using the PBH mass spectra, we further calculate the neutrino and photon energy spectra in extragalactic space from evaporation of light PBHs, and the energy density fraction contained in PBHs today (for heavier PBHs). We obtain the constraints on the model parameters using available experimental data (including data on neutrino and photon cosmic backgrounds). We briefly discuss the possibility that the observed 511 keV line from the Galactic center is produced by annihilation of positrons evaporated by PBHs.

  3. The metric and curvature properties of H-space

    International Nuclear Information System (INIS)

    Hansen, R.O.; Newman, E.T.; Penrose, R.; Tod, K.P.

    1978-01-01

    The space H of asymptotically (left-) shear-free cuts of the future null infinity (good cuts) of an asymptotically flat space-time M is defined. The connection between this space and the asymptotic projective twistor space of M is discussed, and this relation is used to prove that H is four-complex-dimensional for sufficiently 'calm' gravitational radiation in M. The metric on H-space is defined by a simple contour integral expression and is found to be complex Riemannian. The good cut equation governing H-space is solved to three orders by a Taylor series and the solution is used to demonstrate that the curvature of H-space is always a self dual (left flat) solution of the Einstein vacuum equations. (author)

  4. Generalized curvature and the equations of D=11 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Igor A. [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Institute for Theoretical Physics, NSC ' Kharkov Institute of Physics and Technology' , UA-61108 Kharkov (Ukraine); Azcarraga, Jose A. de [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain)]. E-mail: j.a.de.azcarraga@ific.uv.es; Picon, Moises [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Department of Physics and Astronomy, University of Southern California, Los Angeles, CA 90089-2535 (United States); Varela, Oscar [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Michigan Center for Theoretical Physics, Randall Laboratory, Department of Physics, University of Michigan, Ann Arbor, MI 48109-1120 (United States)

    2005-05-26

    It is known that, for zero fermionic sector, {psi}{sub {mu}}{sup {alpha}}(x)=0, the bosonic equations of Cremmer-Julia-Scherk eleven-dimensional supergravity can be collected in a compact expression, Rab{alpha}{gamma}{gamma}b{gamma}{beta}=0, which is a condition on the curvature R{alpha}{beta} of the generalized connection w. In this Letter we show that the equation Rbc{alpha}{gamma}{gamma}abc{gamma}{beta}=4i((D-bar {psi}){sub bc}{gamma}{sup [abc{sub {beta}({psi}{sub d}{gamma}{sup d}]){sub {alpha}}), where D-bar is the covariant derivative for the generalized connection w, collects all the bosonic equations of D=11 supergravity when the gravitino is nonvanishing, {psi}{sub {mu}}{sup {alpha}}(x)<>0.

  5. Curvature-driven morphing of non-Euclidean shells

    Science.gov (United States)

    Pezzulla, Matteo; Stoop, Norbert; Jiang, Xin; Holmes, D. P.

    2017-05-01

    We investigate how thin structures change their shape in response to non-mechanical stimuli that can be interpreted as variations in the structure's natural curvature. Starting from the theory of non-Euclidean plates and shells, we derive an effective model that reduces a three-dimensional stimulus to the natural fundamental forms of the mid-surface of the structure, incorporating expansion, or growth, in the thickness. Then, we apply the model to a variety of thin bodies, from flat plates to spherical shells, obtaining excellent agreement between theory and numerics. We show how cylinders and cones can either bend more or unroll, and eventually snap and rotate. We also study the nearly isometric deformations of a spherical shell and describe how this shape change is ruled by the geometry of a spindle. As the derived results stem from a purely geometrical model, they are general and scalable.

  6. Higher-curvature corrections to holographic entanglement with momentum dissipation

    Energy Technology Data Exchange (ETDEWEB)

    Tanhayi, M.R. [Islamic Azad University Central Tehran Branch (IAUCTB), Department of Physics, Faculty of Basic Science, Tehran (Iran, Islamic Republic of); Institute for Research in Fundamental Sciences (IPM), School of Physics, Tehran (Iran, Islamic Republic of); Vazirian, R. [Islamic Azad University Central Tehran Branch (IAUCTB), Department of Physics, Faculty of Basic Science, Tehran (Iran, Islamic Republic of)

    2018-02-15

    We study the effects of Gauss-Bonnet corrections on some nonlocal probes (entanglement entropy, n-partite information and Wilson loop) in the holographic model with momentum relaxation. Higher-curvature terms as well as scalar fields make in fact nontrivial corrections to the coefficient of the universal term in entanglement entropy. We use holographic methods to study such corrections. Moreover, holographic calculation indicates that mutual and tripartite information undergo a transition beyond which they identically change their values. We find that the behavior of the transition curves depends on the sign of the Gauss-Bonnet coupling λ. The transition for λ > 0 takes place in larger separation of subsystems than that of λ < 0. Finally, we examine the behavior of modified part of the force between external point-like objects as a function of Gauss-Bonnet coupling and its sign. (orig.)

  7. Canonical quantization of a relativistic particle with curvature and torsion

    International Nuclear Information System (INIS)

    Nesterenko, V.V.

    1991-01-01

    A generalization of the relativistic particle action is considered. It contain, in addition to the length of the world trajectory, the integrals along the world curve of its curvature and torsion. The generalized Hamiltonian formalism for this model in the D-dimensional space-time is constructed. A complete set of the constraints in the phase space is obtained and their division into the first-class and the second-class constraints is accomplished. On this basis the canonical quantization of the model is fulfilled. For D=3 the mass spectrum is obtained in the sector without tachyonic states, the mass of the state being dependent on its spin. It is shown that in the framework of this model when D=3 the possibility to describe the states with integral, half-odd-integral and continuous spins is derived. Interaction with an external Abelian gauge field introduced in the geometrical way. 21 refs

  8. The string model with the extrinsic curvature term

    International Nuclear Information System (INIS)

    Itoi, C.; Kubota, Hiroshi

    1988-01-01

    The string model with the extrinsic curvature is studied which is a gauge invariant field theory with higher order derivatives. We present an equivalent action without any higher order derivatives which keeps the gauge invariance. We point out the difficulty caused by the second class constraints in Dirac's canonical method. Following a new method for dynamical systems with second class constraints, we construct a equivalent model which has no second class constraints but has a new gauge invariance. This gauge invariance guarantees the equivalence between the original model and new one. We show that the model can be quantized in this formalism. In a simple model, we show the nilpotence of the BRST charge under certain conditions, and discuss the unitarity of the theory. (author)

  9. Inflation in non-minimal matter-curvature coupling theories

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, C.; Bertolami, O. [Departamento de Física e Astronomia and Centro de Física do Porto, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre s/n, 4169-007 Porto (Portugal); Rosa, J.G., E-mail: claudio.gomes@fc.up.pt, E-mail: joao.rosa@ua.pt, E-mail: orfeu.bertolami@fc.up.pt [Departamento de Física da Universidade de Aveiro and CIDMA, Campus de Santiago, 3810-183 Aveiro (Portugal)

    2017-06-01

    We study inflationary scenarios driven by a scalar field in the presence of a non-minimal coupling between matter and curvature. We show that the Friedmann equation can be significantly modified when the energy density during inflation exceeds a critical value determined by the non-minimal coupling, which in turn may considerably modify the spectrum of primordial perturbations and the inflationary dynamics. In particular, we show that these models are characterised by a consistency relation between the tensor-to-scalar ratio and the tensor spectral index that can differ significantly from the predictions of general relativity. We also give examples of observational predictions for some of the most commonly considered potentials and use the results of the Planck collaboration to set limits on the scale of the non-minimal coupling.

  10. Design of footbridge with double curvature made of UHPC

    Science.gov (United States)

    Kněž, P.; Tej, P.; Čítek, D.; Kolísko, J.

    2017-09-01

    This paper presents design of footbridge with double curvature made of UHPC. The structure is designed as a single-span bridge. The span of the bridge is 10.00 m, and the width of the deck is 1.50 m. The thickness of shell structure is 0.03 m for walls and 0.045 m for deck. The main structure of the bridge is one arch shell structure with sidewalls made of UHPC with dispersed steel fibers with conventional reinforcement only at anchoring areas. The structure was designed on the basis of the numerical model. Model was subsequently clarified on the basis of the first test elements. Paper presents detailed course on design of the bridge and presentation will contain also installation in landscape and results of static and dynamic loading tests.

  11. Non-Gaussianities and curvature perturbations from hybrid inflation

    Science.gov (United States)

    Clesse, Sébastien; Garbrecht, Björn; Zhu, Yi

    2014-03-01

    For the original hybrid inflation as well as the supersymmetric F-term and D-term hybrid models, we calculate the level of non-Gaussianities and the power spectrum of curvature perturbations generated during the waterfall, taking into account the contribution of entropic modes. We focus on the regime of mild waterfall, in which inflation continues for more than about 60 e-folds N during the waterfall. We find that the associated fNL parameter goes typically from fNL≃-1/Nexit in the regime with N ≫60, where Nexit is the number of e-folds between the time of Hubble exit of a pivot scale and the end of inflation, down to fNL˜-0.3 when N ≳60, i.e., much smaller in magnitude than the current bound from Planck. Considering only the adiabatic perturbations, the power spectrum is red, with a spectral index ns=1-4/Nexit in the case N ≫60, whereas in the case N≳60, it increases up to unity. Including the contribution of entropic modes does not change observable predictions in the first case, and the spectral index is too low for this regime to be viable. In the second case, entropic modes are a relevant source for the power spectrum of curvature perturbations, of which the amplitude increases by several orders of magnitude. When spectral index values are consistent with observational constraints, the primordial spectrum amplitude is much larger than the observed value and can even lead to black hole formation. We conclude that, due to the important contribution of entropic modes, the parameter space leading to a mild waterfall phase is excluded by cosmic microwave background observations for all the considered models.

  12. Nonlinear damping of drift waves by strong flow curvature

    International Nuclear Information System (INIS)

    Sidikman, K.L.; Carreras, B.A.; Garcia, L.; Diamond, P.H.

    1993-01-01

    A single-equation model has been used to study the effect of a fixed poloidal flow (V 0 ) on turbulent drift waves. The electron dynamics come from a laminar kinetic equation in the dissipative trapped-electron regime. In the past, the authors have assumed that the mode frequency is close to the drift-wave frequency. Trapped-electron density fluctuations are then related to potential fluctuations by an open-quotes iδclose quotes term. Flow shear (V 0 ') and curvature (V 0 double-prime) both have a stabilizing effect on linear modes for this open-quotes iδclose quotes model. However, in the nonlinear regime, single-helicity effects inhibit the flow damping. Neither V 0 ' nor V 0 double-prime produces a nonlinear damping effect. The above assumption on the frequency can be relaxed by including the electron time-response in the linear part of the evolution. In this time-dependent model, instability drive due to trapped electrons is reduced when mode frequency is greater than drift-wave frequency. Since V 0 double-prime produces such a frequency shift, its linear effect is enhanced. There is also nonlinear damping, since single-helicity effects do not eliminate the shift. Renormalized theory for this model predicts nonlinear stability for sufficiently large curvature. Single-helicity calculations have already shown nonlinear damping, and this strong V 0 double-prime regime is being explored. In the theory, the Gaussian shape of the nonlinear diffusivity is expanded to obtain a quadratic potential. The implications of this assumption will be tested by solving the full renormalized equation using a shooting method

  13. Hamilton's equations for a fluid membrane: axial symmetry

    International Nuclear Information System (INIS)

    Capovilla, R; Guven, J; Rojas, E

    2005-01-01

    Consider a homogeneous fluid membrane, or vesicle, described by the Helfrich-Canham energy, quadratic in the mean curvature. When the membrane is axially symmetric, this energy can be viewed as an 'action' describing the motion of a particle; the contours of equilibrium geometries are identified with particle trajectories. A novel Hamiltonian formulation of the problem is presented which exhibits the following two features: (i) the second derivatives appearing in the action through the mean curvature are accommodated in a natural phase space and (ii) the intrinsic freedom associated with the choice of evolution parameter along the contour is preserved. As a result, the phase space involves momenta conjugate not only to the particle position but also to its velocity, and there are constraints on the phase space variables. This formulation provides the groundwork for a field theoretical generalization to arbitrary configurations, with the particle replaced by a loop in space

  14. A balance between membrane elasticity and polymerization energy sets the shape of spherical clathrin coats

    Science.gov (United States)

    Saleem, Mohammed; Morlot, Sandrine; Hohendahl, Annika; Manzi, John; Lenz, Martin; Roux, Aurélien

    2015-02-01

    In endocytosis, scaffolding is one of the mechanisms to create membrane curvature by moulding the membrane into the spherical shape of the clathrin cage. However, the impact of membrane elastic parameters on the assembly and shape of clathrin lattices has never been experimentally evaluated. Here, we show that membrane tension opposes clathrin polymerization. We reconstitute clathrin budding in vitro with giant unilamellar vesicles (GUVs), purified adaptors and clathrin. By changing the osmotic conditions, we find that clathrin coats cause extensive budding of GUVs under low membrane tension while polymerizing into shallow pits under moderate tension. High tension fully inhibits polymerization. Theoretically, we predict the tension values for which transitions between different clathrin coat shapes occur. We measure the changes in membrane tension during clathrin polymerization, and use our theoretical framework to estimate the polymerization energy from these data. Our results show that membrane tension controls clathrin-mediated budding by varying the membrane budding energy.

  15. Axionic membranes

    International Nuclear Information System (INIS)

    Aurilia, A.; Spallucci, E.

    1992-01-01

    A metal ring removed from a soap-water solution encloses a film of soap which can be mathematically described as a minimal surface having the ring as its only boundary. This is known to everybody. In this letter we suggest a relativistic extension of the above fluidodynamic system where the soap film is replaced by a Kalb-Ramand gauge potential B μν (x) and the ring by a closed string. The interaction between the B μν field and the string current excites a new configuration of the system consisting of a relativistic membrane bounded by the string. We call such a classical solution of the equation of motion an axionic membrane. As a dynamical system, the axionic membrane admits a Hamilton-Jacobi formulation which is an extension of the HJ theory of electromagnetic strings. (orig.)

  16. Metamaterial membranes

    International Nuclear Information System (INIS)

    Restrepo-Flórez, Juan Manuel; Maldovan, Martin

    2017-01-01

    We introduce a new class of metamaterial device to achieve separation of compounds by using coordinate transformations and metamaterial theory. By rationally designing the spatial anisotropy for mass diffusion, we simultaneously concentrate different compounds in different spatial locations, leading to separation of mixtures across a metamaterial membrane. The separation of mixtures into their constituent compounds is critically important in biophysics, biomedical, and chemical applications. We present a practical case where a mixture of oxygen and nitrogen diffusing through a polymeric planar matrix is separated. This work opens doors to new paradigms in membrane separations via coordinate transformations and metamaterials by introducing novel properties and unconventional mass diffusion phenomena. (paper)

  17. Revealed smooth nontransitive preferences

    DEFF Research Database (Denmark)

    Keiding, Hans; Tvede, Mich

    2013-01-01

    In the present paper, we are concerned with the behavioural consequences of consumers having nontransitive preference relations. Data sets consist of finitely many observations of price vectors and consumption bundles. A preference relation rationalizes a data set provided that for every observed...... consumption bundle, all strictly preferred bundles are more expensive than the observed bundle. Our main result is that data sets can be rationalized by a smooth nontransitive preference relation if and only if prices can normalized such that the law of demand is satisfied. Market data sets consist of finitely...... many observations of price vectors, lists of individual incomes and aggregate demands. We apply our main result to characterize market data sets consistent with equilibrium behaviour of pure-exchange economies with smooth nontransitive consumers....

  18. Consumers’ preferences for bread

    DEFF Research Database (Denmark)

    Edenbrandt, Anna Kristina; Gamborg, Christian; Thorsen, Bo Jellesmark

    2017-01-01

    Consumers are apprehensive about transgenic technologies, so cisgenics, which limit gene transfers to sexually compatible organisms, have been suggested to address consumer concerns. We study consumer preferences for rye bread alternatives based on transgenic or cisgenic rye, grown conventionally...

  19. Teachers' preferences towards textbook

    Directory of Open Access Journals (Sweden)

    Stanojević Darko D.

    2016-01-01

    Full Text Available In this paper, using the method named Conjoint analysis, and with the goal of determining teacher's preferences in the process of textbook selection, and also defining the prototype of quality textbook which will could be used in the classroom. With consideration of criteria defined in the previous researches on this topic, an continuing the work on those results, we will create clear hypothetical prototype of the textbook which will satisfy the teacher's preference.

  20. Effect of low levels of lipid oxidation on the curvature, dynamics, and permeability of lipid bilayers and their interactions with cationic nanoparticles

    Science.gov (United States)

    Lee, Hwankyu; Malmstadt, Noah

    2018-04-01

    Lipid bilayers composed of saturated and unsaturated lipids, oxidized lipids, and cholesterol at concentrations of 0–18 mol% oxidized lipid were simulated, showing that the presence of oxidized lipid increases bilayer disorder, curvature, and lateral dynamics at low oxidized-lipid concentrations of 18 mol% or less. The aldehyde terminal of a shortened oxidized-lipid tail tends to interact with water and thus bends toward the bilayer-water interface, in agreement with previous experiments and simulations. In particular, water molecules pass through the oxidized bilayer without pore formation, implying passive permeability. A single nanoparticle, which consists of 300 polystyrene (PS) chains with cationic terminals, added to this bilayer simulation induces negative bilayer curvature and inserts to the bilayer, regardless of the oxidized-lipid concentration. Hydrophobic monomers and cationic terminals of the PS particle interact respectively with lipid tails and headgroups, leading to the wrapping of either lipid monolayer or bilayer along the particle surface. These results indicate that lipid oxidation increases membrane curvature and permeability even at such a low concentration of oxidized lipid, which supports the experimental observations regarding the passive permeability of oxidized bilayer, and also that oxidized lipids of low concentration do not significantly influence the insertion of a cationic PS particle to the bilayer.

  1. Flow Curvature Effects for VAWT: a Review of Virtual Airfoil Transformations and Implementation in XFOIL

    DEFF Research Database (Denmark)

    van der Horst, Sander; van de Wiel, Jelmer E.; Ferreira, Carlos Simao

    2016-01-01

    Blades on a Vertical Axis Wind Turbine (VAWT) experience curved streamlines, caused by the rotation of the turbine. This phenomenon is known as flow curvature and has effects on the aerodynamic loading of the blades. Several authors have proposed methods to account for flow curvature, resulting...

  2. Nonsmooth differential geometry-an approach tailored for spaces with Ricci curvature bounded from below

    CERN Document Server

    Gigli, Nicola

    2018-01-01

    The author discusses in which sense general metric measure spaces possess a first order differential structure. Building on this, spaces with Ricci curvature bounded from below a second order calculus can be developed, permitting the author to define Hessian, covariant/exterior derivatives and Ricci curvature.

  3. Measurements of the Curvature of Protrusions/Retrusions on Migrating Recrystallization Boundaries

    DEFF Research Database (Denmark)

    Zhang, Yubin; Godfrey, A.; Juul Jensen, Dorte

    2009-01-01

    Two methods to quantify protrusions/retrusions and to estimate local boundary curvature from sample plane sections are proposed. The methods are used to evaluate the driving force due to curvature of the protrusions/retrusions for partially recrystallized pure nickel cold rolled to 96% reduction...

  4. The zero curvature formulation of the KP and the sKP equations

    International Nuclear Information System (INIS)

    Barcelos Neto, J.; Das, A.; Panda, S.; Roy, S.

    1992-01-01

    The Kadomtsev-Petviashvili equation is derived from the zero curvature condition associated with the gauge group SL(2,R) in 2+1 dimensions. A fermionic extension of the KP equation is also obtained using the zero curvature condition of the super group OS p (2/1), which reduces upon appropriate restriction to the Kupershmidt equation. (author). 17 refs

  5. Accuracy evaluation of automatic quantification of the articular cartilage surface curvature from MRI

    DEFF Research Database (Denmark)

    Folkesson, Jenny; Dam, Erik B; Olsen, Ole F

    2007-01-01

    for intersubject comparisons. Digital phantoms were created to establish the accuracy of the curvature estimation methods. RESULTS: A comparison of the two curvature estimation methods to ground truth yielded absolute pairwise differences of 1.1%, and 4.8%, respectively. The interscan reproducibility for the two...

  6. Biharmonic Submanifolds with Parallel Mean Curvature Vector in Pseudo-Euclidean Spaces

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Yu, E-mail: yufudufe@gmail.com [Dongbei University of Finance and Economics, School of Mathematics and Quantitative Economics (China)

    2013-12-15

    In this paper, we investigate biharmonic submanifolds in pseudo-Euclidean spaces with arbitrary index and dimension. We give a complete classification of biharmonic spacelike submanifolds with parallel mean curvature vector in pseudo-Euclidean spaces. We also determine all biharmonic Lorentzian surfaces with parallel mean curvature vector field in pseudo-Euclidean spaces.

  7. Constant scalar curvature hypersurfaces in (3 + 1) -dimensional GHMC Minkowski spacetimes

    Science.gov (United States)

    Smith, Graham

    2018-06-01

    We prove that every (3 + 1) -dimensional flat GHMC Minkowski spacetime which is not a translation spacetime or a Misner spacetime carries a unique foliation by spacelike hypersurfaces of constant scalar curvature. In other words, we prove that every such spacetime carries a unique time function with isochrones of constant scalar curvature. Furthermore, this time function is a smooth submersion.

  8. Biharmonic Submanifolds with Parallel Mean Curvature Vector in Pseudo-Euclidean Spaces

    International Nuclear Information System (INIS)

    Fu, Yu

    2013-01-01

    In this paper, we investigate biharmonic submanifolds in pseudo-Euclidean spaces with arbitrary index and dimension. We give a complete classification of biharmonic spacelike submanifolds with parallel mean curvature vector in pseudo-Euclidean spaces. We also determine all biharmonic Lorentzian surfaces with parallel mean curvature vector field in pseudo-Euclidean spaces

  9. Quantum statistical mechanics of nonrelativistic membranes: crumpling transition at finite temperature

    Science.gov (United States)

    Borelli, M. E. S.; Kleinert, H.; Schakel, Adriaan M. J.

    2000-03-01

    The effect of quantum fluctuations on a nearly flat, nonrelativistic two-dimensional membrane with extrinsic curvature stiffness and tension is investigated. The renormalization group analysis is carried out in first-order perturbative theory. In contrast to thermal fluctuations, which soften the membrane at large scales and turn it into a crumpled surface, quantum fluctuations are found to stiffen the membrane, so that it exhibits a Hausdorff dimension equal to two. The large-scale behavior of the membrane is further studied at finite temperature, where a nontrivial fixed point is found, signaling a crumpling transition.

  10. Effects of curvature and rotation on turbulence in the NASA low-speed centrifugal compressor impeller

    Science.gov (United States)

    Moore, Joan G.; Moore, John

    1992-01-01

    The flow in the NASA Low-Speed Impeller is affected by both curvature and rotation. The flow curves due to the following: (1) geometric curvature, e.g. the curvature of the hub and shroud profiles in the meridional plane and the curvature of the backswept impeller blades; and (2) secondary flow vortices, e.g. the tip leakage vortex. Changes in the turbulence and effective turbulent viscosity in the impeller are investigated. The effects of these changes on three-dimensional flow development are discussed. Two predictions of the flow in the impeller, one with, and one without modification to the turbulent viscosity due to rotation and curvature, are compared. Some experimental and theoretical background for the modified mixing length model of turbulent viscosity will also be presented.

  11. Age Preferences for Professional Helpers.

    Science.gov (United States)

    Furchtgott, Ernest; Busemeyer, Jerome R.

    1981-01-01

    For all occupations except clergyman, a relationship between the age of the respondent and preferred age of the professional existed. Older individuals preferred older service providers with one exception, their physician. Highly educated respondents preferred younger physicians. (Author)

  12. Preference Handling for Artificial Intelligence

    OpenAIRE

    Goldsmith, Judy; University of Kentucky; Junker, Ulrich; ILOG

    2009-01-01

    This article explains the benefits of preferences for AI systems and draws a picture of current AI research on preference handling. It thus provides an introduction to the topics covered by this special issue on preference handling.

  13. Chelating polymeric membranes

    KAUST Repository

    Peinemann, Klaus-Viktor; Villalobos Vazquez de la Parra, Luis Francisco; Hilke, Roland

    2015-01-01

    microporous chelating polymeric membrane. Embodiments include, but are not limited to, microporous chelating polymeric membranes, device comprising the membranes, and methods of using and making the same.

  14. Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells

    DEFF Research Database (Denmark)

    Wüstner, Daniel; Faergeman, Nils J

    2008-01-01

    proximity to the cell membrane. Spatial surface intensity patterns of DHE as well as that of the lipid marker DiIC12 being assessed by statistical image analysis persisted over several minutes in cells having a constant overall curvature. Sites of sterol endocytosis appeared indistinguishable from other...

  15. Measuring shape fluctuations in biological membranes

    International Nuclear Information System (INIS)

    Monzel, C; Sengupta, K

    2016-01-01

    Shape fluctuations of lipid membranes have intrigued cell biologists and physicists alike. In the cellular context, their origin—thermal or active—and their physiological significance are open questions. These small incessant displacements, also called membrane undulations, have mostly been studied in model membranes and membranes of simple cells like erythrocytes. Thermal fluctuations of such membranes have been very well described both theoretically and experimentally; active fluctuations are a topic of current interest. Experimentally, membrane fluctuations are not easy to measure, the main challenge being to develop techniques which are capable of measuring very small displacements at very high speed, and preferably over a large area and long time. Scattering techniques have given access to fluctuations in membrane stacks and a variety of optical microscopy based techniques have been devised to study membrane fluctuations of unilamellar vesicles, erythrocytes and other cells. Among them are flicker spectroscopy, dynamic light scattering, diffraction phase microscopy and reflection interference contrast microscopy. Each of these techniques has its advantages and limitations. Here we review the basic principles of the major experimental techniques used to measure bending or shape fluctuations of biomembranes. We report seminal results obtained with each technique and highlight how these studies furthered our understanding of physical properties of membranes and their interactions. We also discuss suggested role of membrane fluctuations in different biological processes. (topical review)

  16. Chemically triggered ejection of membrane tubules controlled by intermonolayer friction.

    Science.gov (United States)

    Fournier, J-B; Khalifat, N; Puff, N; Angelova, M I

    2009-01-09

    We report a chemically driven membrane shape instability that triggers the ejection of a tubule growing exponentially toward a chemical source. The instability is initiated by a dilation of the exposed monolayer, which is coupled to the membrane spontaneous curvature and slowed down by intermonolayer friction. Our experiments are performed by local delivery of a basic pH solution to a giant vesicle. Quantitative fits of the data give an intermonolayer friction coefficient b approximately 2x10;{9} J s/m;{4}. The exponential growth of the tubule may be explained by a Marangoni stress yielding a pulling force proportional to its length.

  17. The hybrid inflation waterfall and the primordial curvature perturbation

    International Nuclear Information System (INIS)

    Lyth, David H.

    2012-01-01

    Without demanding a specific form for the inflaton potential, we obtain an estimate of the contribution to the curvature perturbation generated during the linear era of the hybrid inflation waterfall. The spectrum of this contribution peaks at some wavenumber k = k * , and goes like k 3 for k * , making it typically negligible on cosmological scales. The scale k * can be outside the horizon at the end of inflation, in which case ζ = −(g 2 −(g 2 )) with g gaussian. Taking this into account, the cosmological bound on the abundance of black holes is likely to be satisfied if the curvaton mass m much bigger than the Hubble parameter H, but is likely to be violated if m∼< H. Coming to the contribution to ζ from the rest of the waterfall, we are led to consider the use of the 'end-of-inflation' formula, giving the contribution to ζ generated during a sufficiently sharp transition from nearly-exponential inflation to non-inflation, and we state for the first time the criterion for the transition to be sufficiently sharp. Our formulas are applied to supersymmetric GUT inflation and to supernatural/running-mass inflation

  18. Entropy bound and causality violation in higher curvature gravity

    International Nuclear Information System (INIS)

    Neupane, Ishwaree P; Dadhich, Naresh

    2009-01-01

    In any quantum theory of gravity we do expect corrections to Einstein gravity to occur. Yet, at a fundamental level, it is not apparent what the most relevant corrections are. We argue that the generic curvature square corrections present in the lower dimensional actions of various compactified string theories provide a natural passage between the classical and quantum realms of gravity. The Gauss-Bonnet and (Riemann) 2 gravities, in particular, provide concrete examples in which inconsistency of a theory, such as a violation of microcausality, and a classical limit on black hole entropy are correlated. In such theories the ratio of the shear viscosity to the entropy density, η/s, can be smaller than for a boundary conformal field theory with Einstein gravity dual. This result is interesting from the viewpoint that nuclear matter or quark-gluon plasma produced (such as at RHIC) under extreme densities and temperatures may violate the conjectured KSS bound η/s ≥ 1/4π, albeit marginally so.

  19. Warps, grids and curvature in triple vector bundles

    Science.gov (United States)

    Flari, Magdalini K.; Mackenzie, Kirill

    2018-06-01

    A triple vector bundle is a cube of vector bundle structures which commute in the (strict) categorical sense. A grid in a triple vector bundle is a collection of sections of each bundle structure with certain linearity properties. A grid provides two routes around each face of the triple vector bundle, and six routes from the base manifold to the total manifold; the warps measure the lack of commutativity of these routes. In this paper we first prove that the sum of the warps in a triple vector bundle is zero. The proof we give is intrinsic and, we believe, clearer than the proof using decompositions given earlier by one of us. We apply this result to the triple tangent bundle T^3M of a manifold and deduce (as earlier) the Jacobi identity. We further apply the result to the triple vector bundle T^2A for a vector bundle A using a connection in A to define a grid in T^2A . In this case the curvature emerges from the warp theorem.

  20. Higher curvature self-interaction corrections to Hawking radiation

    Science.gov (United States)

    Fairoos, C.; Sarkar, Sudipta; Yogendran, K. P.

    2017-07-01

    The purely thermal nature of Hawking radiation from evaporating black holes leads to the information loss paradox. A possible route to its resolution could be if (enough) correlations are shown to be present in the radiation emitted from evaporating black holes. A reanalysis of Hawking's derivation including the effects of self-interactions in general relativity shows that the emitted radiation does deviate from pure thermality; however no correlations exist between successively emitted Hawking quanta. We extend the calculations to Einstein-Gauss-Bonnet gravity and investigate if higher curvature corrections to the action lead to some new correlations in the Hawking spectra. The effective trajectory of a massless shell is determined by solving the constraint equations and the semiclassical tunneling probability is calculated. As in the case of general relativity, the radiation is no longer thermal and there is no correlation between successive emissions. The absence of any extra correlations in the emitted radiations even in Gauss-Bonnet gravity suggests that the resolution of the paradox is beyond the scope of semiclassical gravity.

  1. Cosmology of a holographic induced gravity model with curvature effects

    International Nuclear Information System (INIS)

    Bouhmadi-Lopez, Mariam; Errahmani, Ahmed; Ouali, Taoufiq

    2011-01-01

    We present a holographic model of the Dvali-Gabadadze-Porrati scenario with a Gauss-Bonnet term in the bulk. We concentrate on the solution that generalizes the normal Dvali-Gabadadze-Porrati branch. It is well known that this branch cannot describe the late-time acceleration of the universe even with the inclusion of a Gauss-Bonnet term. Here, we show that this branch in the presence of a Gauss-Bonnet curvature effect and a holographic dark energy with the Hubble scale as the infrared cutoff can describe the late-time acceleration of the universe. It is worthwhile to stress that such an energy density component cannot do the same job on the normal Dvali-Gabadadze-Porrati branch (without Gauss-Bonnet modifications) nor in a standard four-dimensional relativistic model. The acceleration on the brane is also presented as being induced through an effective dark energy which corresponds to a balance between the holographic one and geometrical effects encoded through the Hubble parameter.

  2. Scalar brane backgrounds in higher order curvature gravity

    International Nuclear Information System (INIS)

    Charmousis, Christos; Davis, Stephen C.; Dufaux, Jean-Francois

    2003-01-01

    We investigate maximally symmetric brane world solutions with a scalar field. Five-dimensional bulk gravity is described by a general lagrangian which yields field equations containing no higher than second order derivatives. This includes the Gauss-Bonnet combination for the graviton. Stability and gravitational properties of such solutions are considered, and we particularly emphasise the modifications induced by the higher order terms. In particular it is shown that higher curvature corrections to Einstein theory can give rise to instabilities in brane world solutions. A method for analytically obtaining the general solution for such actions is outlined. Generically, the requirement of a finite volume element together with the absence of a naked singularity in the bulk imposes fine-tuning of the brane tension. A model with a moduli scalar field is analysed in detail and we address questions of instability and non-singular self-tuning solutions. In particular, we discuss a case with a normalisable zero mode but infinite volume element. (author)

  3. The geometry of plane waves in spaces of constant curvature

    International Nuclear Information System (INIS)

    Tran, H.V.

    1988-01-01

    We examined the geometry of possible plane wave fronts in spaces of constant curvature for three cases in which the cosmological constant is positive, zero, or negative. The cosmological constant and a second-order invariant determined by a congruence of null rays were used in the investigation. We embedded the spaces under investigation in a flat five-dimensional space, and studied the null hyperplanes passing through the origin of the flat five-dimensional space. The embedded spaces are represented by quadrics in the five-dimensional space. The plane wave fronts are represented by the intersection of the quadric with null hyperplanes passing through the origin of the five-dimensional space. We concluded that in Minkowski spaces (zero cosmological constant), the plane-fronted waves will intersect if and only if the second-order invariant mentioned above is non-zero. For deSitter spaces (positive cosmological constant), plane-fronted waves will always intersect. For anti-deSitter spaces (negative cosmological constant), plane-fronted waves may but need not intersect

  4. Dual curvature acoustically damped concentrating collector. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, G.A.; Rausch, R.A.

    1980-05-01

    A development program was conducted to investigate the design and performance parameters of a novel, dual curvature, concentrating solar collector. The reflector of the solar collector is achieved with a stretched-film reflective surface that approximates a hyperbolic paraboloid and is capable of line-focusing at concentration ratios ranging from 10 to 20X. A prototype collector was designed based on analytical and experimental component trade-off activities as well as economic analyses of solar thermal heating and cooling systems incorporating this type of collector. A prototype collector incorporating six 0.66 x 1.22 m (2 x 4 ft) was fabricated and subjected to a limited thermal efficiency test program. A peak efficiency of 36% at 121/sup 0/C (250/sup 0/F) was achieved based upon the gross aperture area. Commercialization activities were conducted, including estimated production costs of $134.44/m/sup 2/ ($12.49/ft/sup 2/) for the collector assembly (including a local suntracker and controls) and $24.33/m/sup 2/ ($2.26/ft/sup 2/) for the reflector subassembly.

  5. The hybrid inflation waterfall and the primordial curvature perturbation

    Science.gov (United States)

    Lyth, David H.

    2012-05-01

    Without demanding a specific form for the inflaton potential, we obtain an estimate of the contribution to the curvature perturbation generated during the linear era of the hybrid inflation waterfall. The spectrum of this contribution peaks at some wavenumber k = k*, and goes like k3 for k Lt k*, making it typically negligible on cosmological scales. The scale k* can be outside the horizon at the end of inflation, in which case ζ = -(g2-langg2rang) with g gaussian. Taking this into account, the cosmological bound on the abundance of black holes is likely to be satisfied if the curvaton mass m much bigger than the Hubble parameter H, but is likely to be violated if mlsimH. Coming to the contribution to ζ from the rest of the waterfall, we are led to consider the use of the `end-of-inflation' formula, giving the contribution to ζ generated during a sufficiently sharp transition from nearly-exponential inflation to non-inflation, and we state for the first time the criterion for the transition to be sufficiently sharp. Our formulas are applied to supersymmetric GUT inflation and to supernatural/running-mass inflation. A preliminary version of this paper appeared as arXiv:1107.1681.

  6. The speed-curvature power law in Drosophila larval locomotion.

    Science.gov (United States)

    Zago, Myrka; Lacquaniti, Francesco; Gomez-Marin, Alex

    2016-10-01

    We report the discovery that the locomotor trajectories of Drosophila larvae follow the power-law relationship between speed and curvature previously found in the movements of human and non-human primates. Using high-resolution behavioural tracking in controlled but naturalistic sensory environments, we tested the law in maggots tracing different trajectory types, from reaching-like movements to scribbles. For most but not all flies, we found that the law holds robustly, with an exponent close to three-quarters rather than to the usual two-thirds found in almost all human situations, suggesting dynamic effects adding on purely kinematic constraints. There are different hypotheses for the origin of the law in primates, one invoking cortical computations, another viscoelastic muscle properties coupled with central pattern generators. Our findings are consistent with the latter view and demonstrate that the law is possible in animals with nervous systems orders of magnitude simpler than in primates. Scaling laws might exist because natural selection favours processes that remain behaviourally efficient across a wide range of neural and body architectures in distantly related species. © 2016 The Authors.

  7. The hybrid inflation waterfall and the primordial curvature perturbation

    Energy Technology Data Exchange (ETDEWEB)

    Lyth, David H., E-mail: d.lyth@lancaster.ac.uk [Consortium for Fundamental Physics, Cosmology and Astroparticle Group, Department of Physics, Lancaster University, Lancaster LA1 4YB (United Kingdom)

    2012-05-01

    Without demanding a specific form for the inflaton potential, we obtain an estimate of the contribution to the curvature perturbation generated during the linear era of the hybrid inflation waterfall. The spectrum of this contribution peaks at some wavenumber k = k{sub *}, and goes like k{sup 3} for k << k{sub *}, making it typically negligible on cosmological scales. The scale k{sub *} can be outside the horizon at the end of inflation, in which case ζ = −(g{sup 2}−(g{sup 2})) with g gaussian. Taking this into account, the cosmological bound on the abundance of black holes is likely to be satisfied if the curvaton mass m much bigger than the Hubble parameter H, but is likely to be violated if m∼

  8. Linear response to long wavelength fluctuations using curvature simulations

    Energy Technology Data Exchange (ETDEWEB)

    Baldauf, Tobias; Zaldarriaga, Matias [School of Natural Sciences, Institute for Advanced Study, Princeton, NJ (United States); Seljak, Uroš [Physics Department, Astronomy Department and Lawrence Berkeley National Laboratory, University of California, Berkeley, CA (United States); Senatore, Leonardo, E-mail: baldauf@ias.edu, E-mail: useljak@berkeley.edu, E-mail: senatore@stanford.edu, E-mail: matiasz@ias.edu [Stanford Institute for Theoretical Physics, Stanford University, Stanford, CA (United States)

    2016-09-01

    We study the local response to long wavelength fluctuations in cosmological N -body simulations, focusing on the matter and halo power spectra, halo abundance and non-linear transformations of the density field. The long wavelength mode is implemented using an effective curved cosmology and a mapping of time and distances. The method provides an alternative, more direct, way to measure the isotropic halo biases. Limiting ourselves to the linear case, we find generally good agreement between the biases obtained from the curvature method and the traditional power spectrum method at the level of a few percent. We also study the response of halo counts to changes in the variance of the field and find that the slope of the relation between the responses to density and variance differs from the naïve derivation assuming a universal mass function by approximately 8–20%. This has implications for measurements of the amplitude of local non-Gaussianity using scale dependent bias. We also analyze the halo power spectrum and halo-dark matter cross-spectrum response to long wavelength fluctuations and derive second order halo bias from it, as well as the super-sample variance contribution to the galaxy power spectrum covariance matrix.

  9. Membrane separation of ionic liquid solutions

    Science.gov (United States)

    Campos, Daniel; Feiring, Andrew Edward; Majumdar, Sudipto; Nemser, Stuart

    2015-09-01

    A membrane separation process using a highly fluorinated polymer membrane that selectively permeates water of an aqueous ionic liquid solution to provide dry ionic liquid. Preferably the polymer is a polymer that includes polymerized perfluoro-2,2-dimethyl-1,3-dioxole (PDD). The process is also capable of removing small molecular compounds such as organic solvents that can be present in the solution. This membrane separation process is suitable for drying the aqueous ionic liquid byproduct from precipitating solutions of biomass dissolved in ionic liquid, and is thus instrumental to providing usable lignocellulosic products for energy consumption and other industrial uses in an environmentally benign manner.

  10. Measuring children's food preferences

    DEFF Research Database (Denmark)

    Olsen, Annemarie; Kildegaard, Heidi; Gabrielsen, Gorm

    2012-01-01

    The aim of this study is to investigate if children’s food preferences can be reliable measured by using pictures of foods presented on a computer screen in a conjoint layout.We investigate reproducibility (test–retest) and infer validity by comparison with traditional hedonic evaluations...... juices (tangible products), chosen to span the preference spectrum, were hedonically evaluated for appearance and taste. Finally, an actual product choice was performed by having the children choose between two buns and two juices.Results showed that the computer evaluationswith pictures of foods...... provided reproducible information about the children’s visual food preferences, which were in concordance with both hedonic measures and products choices, and can thus be considered valid....

  11. Hamilton's equations for a fluid membrane

    International Nuclear Information System (INIS)

    Capovilla, R; Guven, J; Rojas, E

    2005-01-01

    Consider a homogeneous fluid membrane described by the Helfrich-Canham energy, quadratic in the mean curvature of the membrane surface. The shape equation that determines equilibrium configurations is fourth order in derivatives and cubic in the mean curvature. We introduce a Hamiltonian formulation of this equation which dismantles it into a set of coupled first-order equations. This involves interpreting the Helfrich-Canham energy as an action; equilibrium surfaces are generated by the evolution of space curves. Two features complicate the implementation of a Hamiltonian framework. (i) The action involves second derivatives. This requires treating the velocity as a phase-space variable and the introduction of its conjugate momentum. The canonical Hamiltonian is constructed on this phase space. (ii) The action possesses a local symmetry-reparametrization invariance. The two labels we use to parametrize points on the surface are themselves physically irrelevant. This symmetry implies primary constraints, one for each label, that need to be implemented within the Hamiltonian. The two Lagrange multipliers associated with these constraints are identified as the components of the acceleration tangential to the surface. The conservation of the primary constraints implies two secondary constraints, fixing the tangential components of the momentum conjugate to the position. Hamilton's equations are derived and the appropriate initial conditions on the phase-space variables are identified. Finally, it is shown how the shape equation can be reconstructed from these equations

  12. Enterprise Mac Managed Preferences

    CERN Document Server

    Marczak, Edward

    2010-01-01

    Many systems administrators on the Mac need a way to manage machine configuration after initial setup and deployment. Apple's Managed Preferences system (also known as MCX) is under-documented, often misunderstood, and sometimes outright unknown by sys admins. MCX is usually deployed in conjunction with an OS X server, but it can also be used in Windows environments or where no dedicated server exists at all. Enterprise Mac Managed Preferences is the definitive guide to Apple's Managed Client technology. With this book, you'll get the following: * An example-driven guide to Mac OS X Managed Pr

  13. Effects on Buildings of Surface Curvature Caused by Underground Coal Mining

    Directory of Open Access Journals (Sweden)

    Haifeng Hu

    2016-08-01

    Full Text Available Ground curvature caused by underground mining is one of the most obvious deformation quantities in buildings. To study the influence of surface curvature on buildings and predict the movement and deformation of buildings caused by ground curvature, a prediction model of the influence function on mining subsidence was used to establish the relationship between surface curvature and wall deformation. The prediction model of wall deformation was then established and the surface curvature was obtained from mining subsidence prediction software. Five prediction lines were set up in the wall from bottom to top and the predicted deformation of each line was used to calculate the crack positions in the wall. Thus, the crack prediction model was obtained. The model was verified by a case study from a coalmine in Shanxi, China. The results show that when the ground curvature is positive, the crack in the wall is shaped like a “V”; when the ground curvature is negative, the crack is shaped like a “∧”. The conclusion provides the basis for a damage evaluation method for buildings in coalmine areas.

  14. Experimental and numerical investigation of laser forming of cylindrical surfaces with arbitrary radius of curvature

    Directory of Open Access Journals (Sweden)

    Mehdi Safari

    2016-09-01

    Full Text Available In this work, laser forming of cylindrical surfaces with arbitrary radius of curvature is investigated experimentally and numerically. For laser forming of cylindrical surfaces with arbitrary radius of curvature, a new and comprehensive method is proposed in this paper. This method contains simple linear irradiating lines and using an analytical method, required process parameters for laser forming of a cylindrical surface with a specific radius of curvature is proposed. In this method, laser output power, laser scanning speed and laser beam diameter are selected based on laser machine and process limitations. As in the laser forming of a cylindrical surface, parallel irradiating lines are needed; therefore key parameter for production of a cylindrical surface with a specific radius of curvature is the number of irradiating lines. Hence, in the proposed analytical method, the required number of irradiating lines for production of a cylindrical surface with a specific radius of curvature is suggested. Performance of the proposed method for production of cylindrical surface with a specific radius of curvature is verified with experimental tests. The results show that using proposed analytical method, cylindrical surfaces with any radius of curvature can be produced successfully.

  15. Long-term Results of Ventral Penile Curvature Repair in Childhood.

    Science.gov (United States)

    Golomb, Dor; Sivan, Bezalel; Livne, Pinhas M; Nevo, Amihay; Ben-Meir, David

    2018-02-01

    To assess the postpubertal outcome of ventral penile curvature repaired in infancy in terms of recurrence and aesthetics. Postpubertal patients treated for hypospadias and ventral penile curvature in infancy at a tertiary medical center were invited to undergo assessment of the quality of the repair. Findings were compared between patients with a straight penis after skin release and patients who required dorsal plication. The cohort included 27 patients of mean age 16.5 years who were reported with straight penis after surgery. Postpubertal curvature was found in 6 of 14 patients (43%) successfully treated by skin release and 10 of 13 patients (77%) who underwent dorsal plication (P = .087). Significant curvature (≥30 degrees) was found in 1 of 14 patients in the skin-release group and 4 of 13 in the dorsal plication group (P = .16). Rates of redo urethroplasty were 2 of 14 (14%) and 5 of 10 (50%), respectively. Patient satisfaction with the appearance of the penis did not differ significantly. Ventral penile curvature repaired in infancy often recurs after puberty. The need for dorsal plication has a trend-level association with recurrence of penile curvature in puberty. It might also be related to the degree of postpubertal penile curvature and the need for redo urethroplasty. Procedure type does not affect patient satisfaction with the postpubertal appearance of the penis. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Quantitative analysis and prediction of curvature in leucine-rich repeat proteins.

    Science.gov (United States)

    Hindle, K Lauren; Bella, Jordi; Lovell, Simon C

    2009-11-01

    Leucine-rich repeat (LRR) proteins form a large and diverse family. They have a wide range of functions most of which involve the formation of protein-protein interactions. All known LRR structures form curved solenoids, although there is large variation in their curvature. It is this curvature that determines the shape and dimensions of the inner space available for ligand binding. Unfortunately, large-scale parameters such as the overall curvature of a protein domain are extremely difficult to predict. Here, we present a quantitative analysis of determinants of curvature of this family. Individual repeats typically range in length between 20 and 30 residues and have a variety of secondary structures on their convex side. The observed curvature of the LRR domains correlates poorly with the lengths of their individual repeats. We have, therefore, developed a scoring function based on the secondary structure of the convex side of the protein that allows prediction of the overall curvature with a high degree of accuracy. We also demonstrate the effectiveness of this method in selecting a suitable template for comparative modeling. We have developed an automated, quantitative protocol that can be used to predict accurately the curvature of leucine-rich repeat proteins of unknown structure from sequence alone. This protocol is available as an online resource at http://www.bioinf.manchester.ac.uk/curlrr/.

  17. Differential geometric structures of stream functions: incompressible two-dimensional flow and curvatures

    International Nuclear Information System (INIS)

    Yamasaki, K; Iwayama, T; Yajima, T

    2011-01-01

    The Okubo-Weiss field, frequently used for partitioning incompressible two-dimensional (2D) fluids into coherent and incoherent regions, corresponds to the Gaussian curvature of the stream function. Therefore, we consider the differential geometric structures of stream functions and calculate the Gaussian curvatures of some basic flows. We find the following. (I) The vorticity corresponds to the mean curvature of the stream function. Thus, the stream-function surface for an irrotational flow and that for a parallel shear flow correspond to the minimal surface and a developable surface, respectively. (II) The relationship between the coherency and the magnitude of the vorticity is interpreted by the curvatures. (III) Using the Gaussian curvature, stability of single and double point vortex streets is analyzed. The results of this analysis are compared with the well-known linear stability analysis. (IV) Conformal mapping in fluid mechanics is the physical expression of the geometric fact that the sign of the Gaussian curvature does not change in conformal mapping. These findings suggest that the curvatures of stream functions are useful for understanding the geometric structure of an incompressible 2D flow.

  18. Numerical study on the incompressible Euler equations as a Hamiltonian system: Sectional curvature and Jacobi field

    Science.gov (United States)

    Ohkitani, K.

    2010-05-01

    We study some of the key quantities arising in the theory of [Arnold "Sur la geometrie differentielle des groupes de Lie de dimension infinie et ses applications a l'hydrodynamique des fluides parfaits," Annales de l'institut Fourier 16, 319 (1966)] of the incompressible Euler equations both in two and three dimensions. The sectional curvatures for the Taylor-Green vortex and the ABC flow initial conditions are calculated exactly in three dimensions. We trace the time evolution of the Jacobi fields by direct numerical simulations and, in particular, see how the sectional curvatures get more and more negative in time. The spatial structure of the Jacobi fields is compared to the vorticity fields by visualizations. The Jacobi fields are found to grow exponentially in time for the flows with negative sectional curvatures. In two dimensions, a family of initial data proposed by Arnold (1966) is considered. The sectional curvature is observed to change its sign quickly even if it starts from a positive value. The Jacobi field is shown to be correlated with the passive scalar gradient in spatial structure. On the basis of Rouchon's physical-space based expression for the sectional curvature (1984), the origin of negative curvature is investigated. It is found that a "potential" αξ appearing in the definition of covariant time derivative plays an important role, in that a rapid growth in its gradient makes a major contribution to the negative curvature.

  19. The Influence of Shoreline Curvature on Rates of Shoreline Change on Sandy Coasts

    Science.gov (United States)

    Murray, A. B.; Lauzon, R.; Cheng, S.; Liu, J.; Lazarus, E.

    2017-12-01

    The sandy, low-lying barrier islands which characterize much of the US East and Gulf coasts are popular spots to live and vacation, and are often heavily developed. However, sandy shorelines and barriers are also naturally mobile landforms, which are vulnerable to sea level rise and storms and can experience high rates of shoreline change. Many previous studies have attempted to understand and quantify the factors that contribute to those rates of shoreline change, such as grain size, underlying geology, sea level rise, and anthropogenic modification. Shoreline curvature has not been considered in such analyses, but previous research has demonstrated that subtle coastline curvature (and therefore alongshore variation in relative offshore wave angle) can result in gradients in net alongshore transport that cause significant shoreline erosion or accretion. Here we present the results of a spatially extensive analysis of the correlation between shoreline curvature and shoreline change rates for the sandy shorelines of the US East and Gulf coasts. We find that, for wave-dominated sandy coasts where nourishment and shoreline stabilization do not dominate the shoreline change signal (such as parts of Texas, North Carolina, and Florida), there is a significant negative correlation between shoreline curvature and shoreline change rates over 1 - 5 km and decadal to centurial space and time scales. This correlation indicates that a portion of the coastal erosion (and accretion) observed in these areas can be explained by the smoothing of subtle coastline curvature by gradients in alongshore transport, and suggests that shoreline curvature should be included in future attempts to understand historical and future rates of shoreline change. Shoreline stabilization, especially through beach nourishment, complicates the relationship between curvature and shoreline change. Beach construction during nourishment creates a seaward convex curvature in the part of the shoreline moves

  20. Influence of firing time and framework thickness on veneered Y-TZP discs curvature.

    Science.gov (United States)

    Jakubowicz-Kohen, Boris D; Sadoun, Michaël J; Douillard, Thierry; Mainjot, Amélie K

    2014-02-01

    The objective of the present work was to study the curvature of very thinly, veneered Y-TZP discs of different framework thicknesses submitted to different firing times. Fifteen 20-mm-wide Y-TZP discs were produced in three different thicknesses: 0.75, 1, 1.5mm. One disc from each group was left unveneered while the others were layered with a 0.1mm veneering ceramic layer. All discs underwent five firing cycles for a total cumulative firing time of 30 min, 1, 2, 5 and 10h at 900°C. The curvature profile was measured using a profilometer after the veneering process and after each firing cycle respectively. A fitted curve was then used to estimate the, curvature radius. The coefficient of thermal expansion (CTE) measurements were taken on veneering, ceramic and Y-TZP beam samples that underwent the same firing schedule. Those data were used to calculate the curvature generated by CTE variations over firing time. All bilayered samples exhibited a curvature that increased over firing time inversely to framework thickness. However non-veneered samples did not exhibit any curvature modification. The results of the present study reveal that even a very thin veneer layer (0.1mm) can induce a significant curvature of Y-TZP discs. The dilatometric results showed that Tg and CTE, variations are not sufficient to explain this curvature. A chemical-induced zirconia volume, augmentation located at the framework sub-surface near the interface could explain the sample, curvature and its increase with firing time. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  1. Plan curvature and landslide probability in regions dominated by earth flows and earth slides

    Science.gov (United States)

    Ohlmacher, G.C.

    2007-01-01

    Damaging landslides in the Appalachian Plateau and scattered regions within the Midcontinent of North America highlight the need for landslide-hazard mapping and a better understanding of the geomorphic development of landslide terrains. The Plateau and Midcontinent have the necessary ingredients for landslides including sufficient relief, steep slope gradients, Pennsylvanian and Permian cyclothems that weather into fine-grained soils containing considerable clay, and adequate precipitation. One commonly used parameter in landslide-hazard analysis that is in need of further investigation is plan curvature. Plan curvature is the curvature of the hillside in a horizontal plane or the curvature of the contours on a topographic map. Hillsides can be subdivided into regions of concave outward plan curvature called hollows, convex outward plan curvature called noses, and straight contours called planar regions. Statistical analysis of plan-curvature and landslide datasets indicate that hillsides with planar plan curvature have the highest probability for landslides in regions dominated by earth flows and earth slides in clayey soils (CH and CL). The probability of landslides decreases as the hillsides become more concave or convex. Hollows have a slightly higher probability for landslides than noses. In hollows landslide material converges into the narrow region at the base of the slope. The convergence combined with the cohesive nature of fine-grained soils creates a buttressing effect that slows soil movement and increases the stability of the hillside within the hollow. Statistical approaches that attempt to determine landslide hazard need to account for the complex relationship between plan curvature, type of landslide, and landslide susceptibility. ?? 2007 Elsevier B.V. All rights reserved.

  2. Superwetting nanowire membranes for selective absorption.

    Science.gov (United States)

    Yuan, Jikang; Liu, Xiaogang; Akbulut, Ozge; Hu, Junqing; Suib, Steven L; Kong, Jing; Stellacci, Francesco

    2008-06-01

    The construction of nanoporous membranes is of great technological importance for various applications, including catalyst supports, filters for biomolecule purification, environmental remediation and seawater desalination. A major challenge is the scalable fabrication of membranes with the desirable combination of good thermal stability, high selectivity and excellent recyclability. Here we present a self-assembly method for constructing thermally stable, free-standing nanowire membranes that exhibit controlled wetting behaviour ranging from superhydrophilic to superhydrophobic. These membranes can selectively absorb oils up to 20 times the material's weight in preference to water, through a combination of superhydrophobicity and capillary action. Moreover, the nanowires that form the membrane structure can be re-suspended in solutions and subsequently re-form the original paper-like morphology over many cycles. Our results suggest an innovative material that should find practical applications in the removal of organics, particularly in the field of oil spill cleanup.

  3. A high resolution electron microscopy investigation of curvature in carbon nanotubes

    Science.gov (United States)

    Weldon, D. N.; Blau, W. J.; Zandbergen, H. W.

    1995-07-01

    Evidence for heptagon inclusion in multi-walled carbon nanotubes was sought in arc-produced carbon deposits. Transmission electron microscopy revealed many curved nanotubes although their relative abundance was low. Close examination of the micrographs in the regions of expected heptagon inclusion shows that the curvature is accomplished by folding or fracture of the lattice planes. This observed phenomenon contradicts the theoretical modelling studies which predict stable structures with negative curvature accomplished by heptagon/pentagon pairs. A possible explanation for curvature in single-walled tubes is presented based on a molecular mechanics geometry optimisation study of spa inclusion in a graphite sheet.

  4. Embedded positive constant r-mean curvature hypersurfaces in Mm × R

    Directory of Open Access Journals (Sweden)

    Cheng Xu

    2005-01-01

    Full Text Available Let M be an m-dimensional Riemannian manifold with sectional curvature bounded from below. We consider hypersurfaces in the (m + 1-dimensional product manifold M x R with positive constant r-mean curvature. We obtain height estimates of certain compact vertical graphs in M x R with boundary in M x {0}. We apply this to obtain topological obstructions for the existence of some hypersurfaces. We also discuss the rotational symmetry of some embedded complete surfaces in S² x R of positive constant 2-mean curvature.

  5. Curvature contributions to the static electrical properties of push-pull molecules

    International Nuclear Information System (INIS)

    Squitieri, Emilio

    2005-01-01

    Calculations of the curvature contribution to the diagonals components of the static dipole moment (μ), polarizability (α), first (β) and second (γ) hyperpolarizability of push-pull molecules are presented. This contribution was obtained from the analytical evaluation of electrical properties method using the harmonic zero-point energy. The valence-bond charge-transfer model was employed to obtain the field-dependent force constant and their derivates with respect to electric field. Our results show a relationship between the curvature and electronic contributions. We have also found that the curvature contribution is important in a numerical estimation of β and γ

  6. Curvature effects in two-dimensional optical devices inspired by transformation optics

    KAUST Repository

    Yuan, Shuhao

    2016-11-14

    Light transport in curved quasi two-dimensional waveguides is considered theoretically. Within transformation optics and tensor theory, a concise description of curvature effects on transverse electric and magnetic waves is derived. We show that the curvature can induce light focusing and photonic crystal properties, which are confirmed by finite element simulations. Our results indicate that the curvature is an effective parameter for designing quasi two-dimensional optical devices in the fields of micro and nano photonics. © 2016 Author(s).

  7. Shape discrimination by total curvature, with a view to cancer diagnostics

    DEFF Research Database (Denmark)

    Gardner, R.J.; Hobolth, Asger; Jensen, Eva Bjørn Vedel

    2005-01-01

    This paper investigates the use of total curvature for shape discrimination of objects via profiles of their planar sections (not assumed to be star shaped). Methods of estimating total curvature from observation of a finite number of points on the boundary of the object are investigated, includi...... a simple discrete approximation method and various interpolation methods. Total curvature is capable of revealing shape differences on a local scale, as demonstrated by the analysis of two data sets of malignant and normal or benign tumour cell nuclear profiles....

  8. Influence of implant rod curvature on sagittal correction of scoliosis deformity.

    Science.gov (United States)

    Salmingo, Remel Alingalan; Tadano, Shigeru; Abe, Yuichiro; Ito, Manabu

    2014-08-01

    Deformation of in vivo-implanted rods could alter the scoliosis sagittal correction. To our knowledge, no previous authors have investigated the influence of implanted-rod deformation on the sagittal deformity correction during scoliosis surgery. To analyze the changes of the implant rod's angle of curvature during surgery and establish its influence on sagittal correction of scoliosis deformity. A retrospective analysis of the preoperative and postoperative implant rod geometry and angle of curvature was conducted. Twenty adolescent idiopathic scoliosis patients underwent surgery. Average age at the time of operation was 14 years. The preoperative and postoperative implant rod angle of curvature expressed in degrees was obtained for each patient. Two implant rods were attached to the concave and convex side of the spinal deformity. The preoperative implant rod geometry was measured before surgical implantation. The postoperative implant rod geometry after surgery was measured by computed tomography. The implant rod angle of curvature at the sagittal plane was obtained from the implant rod geometry. The angle of curvature between the implant rod extreme ends was measured before implantation and after surgery. The sagittal curvature between the corresponding spinal levels of healthy adolescents obtained by previous studies was compared with the implant rod angle of curvature to evaluate the sagittal curve correction. The difference between the postoperative implant rod angle of curvature and normal spine sagittal curvature of the corresponding instrumented level was used to evaluate over or under correction of the sagittal deformity. The implant rods at the concave side of deformity of all patients were significantly deformed after surgery. The average degree of rod deformation Δθ at the concave and convex sides was 15.8° and 1.6°, respectively. The average preoperative and postoperative implant rod angle of curvature at the concave side was 33.6° and 17.8

  9. Specificity and kinetics of alpha-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe.

    Science.gov (United States)

    Shvadchak, Volodymyr V; Falomir-Lockhart, Lisandro J; Yushchenko, Dmytro A; Jovin, Thomas M

    2011-04-15

    Parkinson disease is characterized cytopathologically by the deposition in the midbrain of aggregates composed primarily of the presynaptic neuronal protein α-synuclein (AS). Neurotoxicity is currently attributed to oligomeric microaggregates subjected to oxidative modification and promoting mitochondrial and proteasomal dysfunction. Unphysiological binding to membranes of these and other organelles is presumably involved. In this study, we performed a systematic determination of the influence of charge, phase, curvature, defects, and lipid unsaturation on AS binding to model membranes using a new sensitive solvatochromic fluorescent probe. The interaction of AS with vesicular membranes is fast and reversible. The protein dissociates from neutral membranes upon thermal transition to the liquid disordered phase and transfers to vesicles with higher affinity. The binding of AS to neutral and negatively charged membranes occurs by apparently different mechanisms. Interaction with neutral bilayers requires the presence of membrane defects; binding increases with membrane curvature and rigidity and decreases in the presence of cholesterol. The association with negatively charged membranes is much stronger and much less sensitive to membrane curvature, phase, and cholesterol content. The presence of unsaturated lipids increases binding in all cases. These findings provide insight into the relation between membrane physical properties and AS binding affinity and dynamics that presumably define protein localization in vivo and, thereby, the role of AS in the physiopathology of Parkinson disease.

  10. Constructive Preference Elicitation

    Directory of Open Access Journals (Sweden)

    Paolo Dragone

    2018-01-01

    Full Text Available When faced with large or complex decision problems, human decision makers (DM can make costly mistakes, due to inherent limitations of their memory, attention, and knowledge. Preference elicitation tools assist the decision maker in overcoming these limitations. They do so by interactively learning the DM’s preferences through appropriately chosen queries and suggesting high-quality outcomes based on the preference estimates. Most state-of-the-art techniques, however, fail in constructive settings, where the goal is to synthesize a custom or entirely novel configuration rather than choosing the best option among a given set of candidates. Many wide-spread problems are constructive in nature: customizing composite goods such as cars and computers, bundling products, recommending touristic travel plans, designing apartments, buildings, or urban layouts, etc. In these settings, the full set of outcomes is humongous and can not be explicitly enumerated, and the solution must be synthesized via constrained optimization. In this article, we describe recent approaches especially designed for constructive problems, outlining the underlying ideas and their differences as well as their limitations. In presenting them, we especially focus on novel issues that the constructive setting brings forth, such as how to deal with sparsity of the DM’s preferences, how to properly frame the interaction, and how to achieve efficient synthesis of custom instances.

  11. Immigrants' location preferences

    DEFF Research Database (Denmark)

    Damm, Anna Piil

    This paper exploits a spatial dispersal policy for refugee immigrants to estimate the importance of local and regional factors for refugees' location preferences. The main results of a mixed proportional hazard competing risks model are that placed refugees react to high regional unemployment...

  12. Hormones and social preferences

    NARCIS (Netherlands)

    Buser, T.

    2011-01-01

    We examine whether social preferences are determined by hormones. We do this by investigating whether markers for the strength of prenatal testosterone exposure (finger length ratios) and current exposure to progesterone and oxytocin (the menstrual cycle) are correlated with choices in social

  13. Preferred Dance Tempo

    DEFF Research Database (Denmark)

    Dahl, Sofia; Huron, David; Brod, Garvin

    2014-01-01

    In two experiments participants tuned a drum machine to their preferred dance tempo. Measurements of height, shoulder width, leg length, and weight were taken for each participant, and their sex recorded. Using a multiple regression analysis, height and leg length combined was found to be the bes...

  14. Membranes as separators of dispersed emulsion phases

    NARCIS (Netherlands)

    Lefferts, A.G.

    1997-01-01

    The reuse or discharge of industrial waste waters, containing small fractions of dispersed oil, requires a purification treatment for which membranes can be used. If only little oil is present, removal of the dispersed phase might be preferable to the more commonly applied removal of the

  15. Curvature perturbation spectra from waterfall transition, black hole constraints and non-Gaussianity

    Energy Technology Data Exchange (ETDEWEB)

    Bugaev, Edgar; Klimai, Peter, E-mail: bugaev@pcbai10.inr.ruhep.ru, E-mail: pklimai@gmail.com [Institute for Nuclear Research, Russian Academy of Sciences, 60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation)

    2011-11-01

    We carried out numerical calculations of a contribution of the waterfall field to the primordial curvature perturbation (on uniform density hypersurfaces) ζ, which is produced during waterfall transition in hybrid inflation scenario. The calculation is performed for a broad interval of values of the model parameters. We show that there is a strong growth of amplitudes of the curvature perturbation spectrum in the limit when the bare mass-squared of the waterfall field becomes comparable with the square of Hubble parameter. We show that in this limit the primordial black hole constraints on the curvature perturbations must be taken into account. It is shown that, in the same limit, peak values of the curvature perturbation spectra are far beyond horizon, and the spectra are strongly non-Gaussian.

  16. Curvature perturbation spectra from waterfall transition, black hole constraints and non-Gaussianity

    International Nuclear Information System (INIS)

    Bugaev, Edgar; Klimai, Peter

    2011-01-01

    We carried out numerical calculations of a contribution of the waterfall field to the primordial curvature perturbation (on uniform density hypersurfaces) ζ, which is produced during waterfall transition in hybrid inflation scenario. The calculation is performed for a broad interval of values of the model parameters. We show that there is a strong growth of amplitudes of the curvature perturbation spectrum in the limit when the bare mass-squared of the waterfall field becomes comparable with the square of Hubble parameter. We show that in this limit the primordial black hole constraints on the curvature perturbations must be taken into account. It is shown that, in the same limit, peak values of the curvature perturbation spectra are far beyond horizon, and the spectra are strongly non-Gaussian

  17. The effects of curvature on the flow field in rapidly rotating gas centrifuges

    International Nuclear Information System (INIS)

    Wood, H.G.; Jordan, J.A.

    1984-01-01

    The effects of curvature on the fluid dynamics of rapidly rotating gas centrifuges are studied. A governing system of a linear partial differential equation and boundary conditions is derived based on a linearization of the equations for viscous compressible flow. This system reduces to the Onsager pancake model if the effects of curvature are neglected. Approximations to the solutions of the governing equations with and without curvature terms are obtained via a finite-element method. Two examples are considered: first where the flow is driven by a thermal gradient at the wall of the centrifuge, and then for the flow being driven by the introduction and removal of mass through the ends of the centrifuge. Comparisons of the results obtained show that, especially for the second example, the inclusion of the terms due to curvature in the model can have an appreciable effect on the solution. (author)

  18. A non-differential elastomer curvature sensor for softer-than-skin electronics

    International Nuclear Information System (INIS)

    Majidi, C; Kramer, R; Wood, R J

    2011-01-01

    We extend soft lithography microfabrication and design methods to introduce curvature sensors that are elastically soft (modulus 0.1–1 MPa) and stretchable (100–1000% strain). In contrast to existing curvature sensors that measure differential strain, sensors in this new class measure curvature directly and allow for arbitrary gauge factor and film thickness. Moreover, each sensor is composed entirely of a soft elastomer (PDMS (polydimethylsiloxane) or Ecoflex ® ) and conductive liquid (eutectic gallium indium, eGaIn) and thus remains functional even when stretched to several times its natural length. The electrical resistance in the embedded eGaIn microchannel is measured as a function of the bending curvature for a variety of sensor designs. In all cases, the experimental measurements are in reasonable agreement with closed-form algebraic approximations derived from elastic plate theory and Ohm's law

  19. A non-differential elastomer curvature sensor for softer-than-skin electronics

    Science.gov (United States)

    Majidi, C.; Kramer, R.; Wood, R. J.

    2011-10-01

    We extend soft lithography microfabrication and design methods to introduce curvature sensors that are elastically soft (modulus 0.1-1 MPa) and stretchable (100-1000% strain). In contrast to existing curvature sensors that measure differential strain, sensors in this new class measure curvature directly and allow for arbitrary gauge factor and film thickness. Moreover, each sensor is composed entirely of a soft elastomer (PDMS (polydimethylsiloxane) or Ecoflex®) and conductive liquid (eutectic gallium indium, eGaIn) and thus remains functional even when stretched to several times its natural length. The electrical resistance in the embedded eGaIn microchannel is measured as a function of the bending curvature for a variety of sensor designs. In all cases, the experimental measurements are in reasonable agreement with closed-form algebraic approximations derived from elastic plate theory and Ohm's law.

  20. Phase-space curvature in spin-orbit-coupled ultracold atomic systems

    Science.gov (United States)

    Armaitis, J.; Ruseckas, J.; Anisimovas, E.

    2017-04-01

    We consider a system with spin-orbit coupling and derive equations of motion which include the effects of Berry curvatures. We apply these equations to investigate the dynamics of particles with equal Rashba-Dresselhaus spin-orbit coupling in one dimension. In our derivation, the adiabatic transformation is performed first and leads to quantum Heisenberg equations of motion for momentum and position operators. These equations explicitly contain position-space, momentum-space, and phase-space Berry curvature terms. Subsequently, we perform the semiclassical approximation and obtain the semiclassical equations of motion. Taking the low-Berry-curvature limit results in equations that can be directly compared to previous results for the motion of wave packets. Finally, we show that in the semiclassical regime, the effective mass of the equal Rashba-Dresselhaus spin-orbit-coupled system can be viewed as a direct effect of the phase-space Berry curvature.

  1. Curvature effects on the electronic and transport properties of semiconductor films

    Science.gov (United States)

    Batista, F. F.; Chaves, Andrey; da Costa, D. R.; Farias, G. A.

    2018-05-01

    Within the effective mass approximation, we study the curvature effects on the electronic and transport properties of semiconductor films. We investigate how the geometry-induced potential resulting exclusively from periodic ripples in the film induces electronic confinement and a superlattice band structure. For fixed curvature parameters, such a confinement can be easily tuned by an external electric field, hence features of the superlattice band structure such as its energy gaps and band curvature can be controlled by an external parameter. We also show that, for some values of curvature and electric field, it is possible to obtain massless Dirac bands for a smooth curved structure. Moreover, we use a wave packet propagation method to demonstrate that the ripples are responsible for a significant inter-sub-band transition, specially for moderate values of the ripple height.

  2. Preputial reconstruction and tubularized incised plate urethroplasty in proximal hypospadias with ventral penile curvature

    Directory of Open Access Journals (Sweden)

    Amilal Bhat

    2010-01-01

    Conclusions : Preputioplasty with TIP is feasible in proximal hypospadias with curvature without increasing the complication rate. Postoperative phimosis can be prevented by on-table testing of the adequacy of preputial skin by 3 stay sutures.

  3. Spinal curvatures of children and adolescents – a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Grabara Małgorzata

    2017-02-01

    Full Text Available Study aim: The aim was to assess the spinal curvatures of primary and lower secondary male and female students from Silesia and to identify individual variations that can determine spinal posture.

  4. The Lp Lp Lp-curvature images of convex bodies and Lp Lp Lp

    Indian Academy of Sciences (India)

    Associated with the Lp-curvature image defined by Lutwak, some inequali- ... theory. With it, Lutwak [10] generalized many affine isoperimetric inequalities from their ... For quick reference, we recall some basic properties of Lp-mixed and dual ...

  5. The Explicit Construction of Einstein Finsler Metrics with Non-Constant Flag Curvature

    Directory of Open Access Journals (Sweden)

    Enli Guo

    2009-04-01

    Full Text Available By using the Hawking Taub-NUT metric, this note gives an explicit construction of a 3-parameter family of Einstein Finsler metrics of non-constant flag curvature in terms of navigation representation.

  6. New curvature-torsion relations through decomposition of the Bianchi identities

    International Nuclear Information System (INIS)

    Davies, J.B.

    1988-01-01

    The Bianchi Identities relating asymmetric curvature to torsion are obtained as a new set of equations governing second-order curvature tensors. The usual contribution of symmetric curvature to the gravitational field is found to be a subset of these identities though with an added contribution due to torsion gradients. The antisymmetric curvature two-tensor is shown to be related to the divergence of the torsion. Using a model of particle-antiparticle pair production, identification of certain torsion components with electroweak fields is proposed. These components obey equations, similar to Maxwell's that are subsets of these linear Bianchi identities. These results are shown to be consistent with gauge and other previous analyses

  7. Endoscopes and robots for tight surgical spaces: use of precurved elastic elements to enhance curvature

    Science.gov (United States)

    Remirez, Andria A.; Webster, Robert J.

    2016-03-01

    Many applications in medicine require flexible surgical manipulators and endoscopes capable of reaching tight curvatures. The maximum curvature these devices can achieve is often restricted either by a strain limit, or by a maximum actuation force that the device's components can tolerate without risking mechanical failure. In this paper we propose the use of precurvature to "bias" the workspace of the device in one direction. Combined with axial shaft rotation, biasing increases the size of the device's workspace, enabling it to reach tighter curvatures than a comparable device without biasing can achieve, while still being able to fully straighten. To illustrate this effect, we describe several example prototype devices which use flexible nitinol strips that can be pushed and pulled to generate bending. We provide a statics model that relates the manipulator curvature to actuation force, and validate it experimentally.

  8. Curvature effects in two-dimensional optical devices inspired by transformation optics

    KAUST Repository

    Yuan, Shuhao; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlö gl, Udo

    2016-01-01

    Light transport in curved quasi two-dimensional waveguides is considered theoretically. Within transformation optics and tensor theory, a concise description of curvature effects on transverse electric and magnetic waves is derived. We show

  9. Principal Curvature Measures Estimation and Application to 3D Face Recognition

    KAUST Repository

    Tang, Yinhang; Li, Huibin; Sun, Xiang; Morvan, Jean-Marie; Chen, Liming

    2017-01-01

    -based local shape descriptors using the sparse representation-based reconstruction method. The proposed method was evaluated on three public databases, i.e. FRGC v2.0, Bosphorus, and Gavab. Experimental results demonstrated that the three principle curvature

  10. On the asymptotically Poincaré-Einstein 4-manifolds with harmonic curvature

    Science.gov (United States)

    Hu, Xue

    2018-06-01

    In this paper, we discuss the mass aspect tensor and the rigidity of an asymptotically Poincaré-Einstein (APE) 4-manifold with harmonic curvature. We prove that the trace-free part of the mass aspect tensor of an APE 4-manifold with harmonic curvature and normalized Einstein conformal infinity is zero. As to the rigidity, we first show that a complete noncompact Riemannian 4-manifold with harmonic curvature and positive Yamabe constant as well as a L2-pinching condition is Einstein. As an application, we then obtain that an APE 4-manifold with harmonic curvature and positive Yamabe constant is isometric to the hyperbolic space provided that the L2-norm of the traceless Ricci tensor or the Weyl tensor is small enough and the conformal infinity is a standard round 3-sphere.

  11. Estimation of Curvature Changes for Steel-Concrete Composite Bridge Using Fiber Bragg Grating Sensors

    Directory of Open Access Journals (Sweden)

    Donghoon Kang

    2013-01-01

    Full Text Available This study is focused on the verification of the key idea of a newly developed steel-concrete composite bridge. The key idea of the proposed bridge is to reduce the design moment by applying vertical prestressing force to steel girders, so that a moment distribution of a continuous span bridge is formed in a simple span bridge. For the verification of the key technology, curvature changes of the bridge should be monitored sequentially at every construction stage. A pair of multiplexed FBG sensor arrays is proposed in order to measure curvature changes in this study. They are embedded in a full-scale test bridge and measured local strains, which are finally converted to curvatures. From the result of curvature changes, it is successfully ensured that the key idea of the proposed bridge, expected theoretically, is viable.

  12. Generalization of the swelling method to measure the intrinsic curvature of lipids

    Science.gov (United States)

    Barragán Vidal, I. A.; Müller, M.

    2017-12-01

    Via computer simulation of a coarse-grained model of two-component lipid bilayers, we compare two methods of measuring the intrinsic curvatures of the constituting monolayers. The first one is a generalization of the swelling method that, in addition to the assumption that the spontaneous curvature linearly depends on the composition of the lipid mixture, incorporates contributions from its elastic energy. The second method measures the effective curvature-composition coupling between the apposing leaflets of bilayer structures (planar bilayers or cylindrical tethers) to extract the spontaneous curvature. Our findings demonstrate that both methods yield consistent results. However, we highlight that the two-leaflet structure inherent to the latter method has the advantage of allowing measurements for mixed lipid systems up to their critical point of demixing as well as in the regime of high concentration (of either species).

  13. The curvature and the algebra of Killing vectors in five-dimensional space

    International Nuclear Information System (INIS)

    Rcheulishvili, G.

    1990-12-01

    This paper presents the Killing vectors for a five-dimensional space with the line element. The algebras which are formed by these vectors are written down. The curvature two-forms are described. (author). 10 refs

  14. Curvature distribution within hillslopes and catchments and its effect on the hydrological response

    NARCIS (Netherlands)

    Bogaart, P.W.; Troch, P.A.A.

    2006-01-01

    Topographic convergence and divergence are first order controls on the hillslope and catchment hydrological response, as evidenced by similarity parameter analyses. Hydrological models often do not take convergence as measured by contour curvature directly into account; instead they use comparable

  15. Preputial reconstruction and tubularized incised plate urethroplasty in proximal hypospadias with ventral penile curvature

    OpenAIRE

    Bhat, Amilal; Gandhi, Ajay; Saxena, Gajendra; Choudhary, Gautam Ram

    2010-01-01

    Aims : Objective of this study was to assess the feasibility and results of preputial reconstruction and tubularized incised plate urethroplasty (TIP) in patients of proximal hypospadias with ventral penile curvature. Materials and Methods : Twenty-seven patients of proximal hypospadias who underwent preputioplasty with TIP were evaluated retrospectively. Ventral curvature was corrected by mobilization of the urethral plate with the corpus spongiosum and the proximal urethra; dorsal plica...

  16. Isometric surfaces with a common mean curvature and the problem of Bonnet pairs

    International Nuclear Information System (INIS)

    Sabitov, Idzhad Kh

    2012-01-01

    Simple methods are used to give new proofs, and sometimes to make them more precise, of basic theorems on isometric surfaces with a common mean curvature, which are usually called Bonnet pairs. The considerations are conducted under the assumption of minimally admissible smoothness of the objects in question, and certain necessary or sufficient criteria are given for the non-existence of Bonnet pairs with a common non-constant mean curvature among compact surfaces. Bibliography: 26 titles.

  17. Asymmetric vibrations of shells of revolution having meridionally varying curvature and thickness

    International Nuclear Information System (INIS)

    Suzuki, Katsuyoshi; Kosawada, Tadashi; Miura, Kazuyuki.

    1988-01-01

    An exact method using power series expansions is presented for solving asymmetric free vibration problems for shells of revolution having meridionally varying curvature and thickness. The gaverning equations of motion and the boundary conditions are derived from the stationary conditions of the Lagrangian of the shells of revolution. The method is demonstrated for shells of revolution having elliptical, cycloidal, parabolical, catenary and hyperbolical meridional curvature. The natural frequencies are numerically calculated for these shells having second degree thickness variation. (author)

  18. First contact: understanding the relationship between hominoid incisor curvature and diet.

    Science.gov (United States)

    Deane, Andrew

    2009-03-01

    Accurately interpreting fossil primate dietary behaviour is necessary to fully understand a species' ecology and connection to its environment. Traditional methods developed to infer diet from hominoid teeth successfully group taxa into broad dietary categories (i.e., folivore, frugivore) but often fail to represent the range of dietary variability characteristic of living apes. This oversimplification is not only a consequence of poor resolution, but may also reflect the use of similar fallback resources by closely related taxa with dissimilar diets. This study demonstrates that additional dietary specificity can be achieved using a morphometric approach to hominoid incisor curvature. High-resolution polynomial curve fitting (HR-PCF) was used to quantify the incisor curvatures of closely related hominoid taxa that have dissimilar diets but similar morphological adaptations to specific keystone resources (e.g., Gorilla gorilla beringei vs. G. g. gorilla). Given the key role of incisors in food processing, it is reasonable to assume that these teeth will be at least partially influenced by the unique selective pressures imposed by the mechanical loading specific to individual diets. Results from this study identify a strong correlation between hominoid dietary proportions and incisor linear dimensions and curvature, indicating that more pronounced incisor curvature is positively correlated with higher levels of frugivory. Hard-object frugivores have the greatest mesiodistal and cervico-incisal curvature and dedicated folivores have the least curved incisors. Mixed folivore/frugivores are morphological intermediates between dedicated folivores and hard- and soft-object frugivores. Mesiodistal curvature varied only in the degree of curvature; however, cervico-incisal curvature was shown to differ qualitatively between more frugivorous and more folivorous taxa. In addition to identifying a greater range of dietary variability among hominoids, this study also

  19. Extensions of the Stoney formula for substrate curvature to configurations with thin substrates or large deformations

    International Nuclear Information System (INIS)

    Freund, L.B.; Floro, J.A.; Chason, E.

    1999-01-01

    Two main assumptions which underlie the Stoney formula relating substrate curvature to mismatch strain in a bonded thin film are that the film is very thin compared to the substrate, and the deformations are infinitesimally small. Expressions for the curvature - strain relationship are derived for cases in which these assumptions are relaxed, thereby providing a basis for interpretation of experimental observations for a broader class of film - substrate configurations. copyright 1999 American Institute of Physics

  20. Distal root curvatures in mandibular molars: analysis using digital panoramic X-rays.

    Science.gov (United States)

    Fuentes, R; Farfán, C; Astete, N; Navarro, P; Arias, A

    2018-01-01

    The aim of this study was to describe the degree of curvature in distal roots in the first and second permanent mandibular molars in a Chilean patient sample. A cross-sectional descriptive study was conducted in which digital panoramic X-rays were analysed. Examinations of patients under 18 years, with signs of distortion or alteration in the contrast or the presence of pathologies that affected visualisation of the roots and pulp-chamber floor of the teeth to be analysed were excluded. Using the AutoCad software, an angle was drawn to represent the curve of the root in its different thirds, drawing lines inside the root canal from the pulp-chamber floor to the dental apex. Using the classic definition of dilaceration (root curvature > 90°), its prevalence was established. 412 teeth and roots were analysed, finding a dilaceration prevalence of 0.73% (n = 3). 84.72% of the roots presented some type of curvature. The middle third had the highest percentage of curvatures and the greatest average of angular curvature, whereas the cervical third was the straightest. No significant differences were found between the degree of curvature and the gender of the subjects, except for the apical third of tooth 3.6. The analysis of curvature by root third offers to the clinician a better perspective of the directional change of the roots and does not limit it to just the presence of curves in the apical third. The report of the angular degree of the curvatures, in addition to the prevalence of dilacerations, informs to the clinicians about the likelihood of finding difficulties when treating root canals. (Folia Morphol 2018; 77, 1: 131-137).

  1. Curvature Dependence of Interfacial Properties for Associating Lennard—Jones Fluids: A Density Functional Study

    International Nuclear Information System (INIS)

    Sun Zong-Li; Kang Yan-Shuang

    2011-01-01

    Classical density functional theory is used to study the associating Lennard—Jones fluids in contact with spherical hard wall of different curvature radii. The interfacial properties including contact density and fluid-solid interfacial tension are investigated. The influences of associating energy, curvature of hard wall and the bulk density of fluids on these properties are analyzed in detail. The results may provide helpful clues to understand the interfacial properties of other complex fluids. (condensed matter: structure, mechanical and thermal properties)

  2. Role of parallel flow curvature on the mitigation of Rayleigh-Taylor instability

    International Nuclear Information System (INIS)

    Sarmah, D.; Sen, S.; Cairns, R.A.

    2001-01-01

    The effect of a radially varying parallel equilibrium flow on the stability of the Rayleigh-Taylor (RT) mode is studied analytically in the presence of a sheared magnetic field. It is shown that the parallel flow curvature can completely stabilize the RT mode. The flow curvature also has a robust effect on the radial structure of the mode. Possible implications of these theoretical findings to recent experiments are also discussed

  3. ORNL Interim Progress Report on Static CIRFT Testing Curvature Data Update

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jy-An John [ORNL; Wang, Hong [ORNL

    2016-10-10

    Since the CIRFT tests reported in NUREG-7198 were generated, a number of factors that influence the recorded curvature measurement data were identified. In 2016, a data reanalysis task was undertaken to implement the lessons learned. This letter report provides the revised results of previous CIRFT tests, after implementing the following data reanalysis procedures: (A) experimental data smoothing and LVDT reset, (B) LVDT probe contact and sensor spacing correction for curvature data, and (C) LVDT probe dynamic vibration adjustment procedure development.

  4. Estimating exponential scheduling preferences

    DEFF Research Database (Denmark)

    Hjorth, Katrine; Börjesson, Maria; Engelson, Leonid

    2015-01-01

    of car drivers' route and mode choice under uncertain travel times. Our analysis exposes some important methodological issues related to complex non-linear scheduling models: One issue is identifying the point in time where the marginal utility of being at the destination becomes larger than the marginal......Different assumptions about travelers' scheduling preferences yield different measures of the cost of travel time variability. Only few forms of scheduling preferences provide non-trivial measures which are additive over links in transport networks where link travel times are arbitrarily...... utility of being at the origin. Another issue is that models with the exponential marginal utility formulation suffer from empirical identification problems. Though our results are not decisive, they partly support the constant-affine specification, in which the value of travel time variability...

  5. Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probes

    DEFF Research Database (Denmark)

    Lundbæk, Jens August; Collingwood, S.A.; Ingolfsson, H.I.

    2010-01-01

    with collective physical properties (e.g. thickness, intrinsic monolayer curvature or elastic moduli). Studies in physico-chemical model systems have demonstrated that changes in bilayer physical properties can regulate membrane protein function by altering the energetic cost of the bilayer deformation associated...... with a protein conformational change. This type of regulation is well characterized, and its mechanistic elucidation is an interdisciplinary field bordering on physics, chemistry and biology. Changes in lipid composition that alter bilayer physical properties (including cholesterol, polyunsaturated fatty acids...... channels as molecular force probes for studying this mechanism, with a unique ability to discriminate between consequences of changes in monolayer curvature and bilayer elastic moduli....

  6. No large scale curvature perturbations during the waterfall phase transition of hybrid inflation

    International Nuclear Information System (INIS)

    Abolhasani, Ali Akbar; Firouzjahi, Hassan

    2011-01-01

    In this paper the possibility of generating large scale curvature perturbations induced from the entropic perturbations during the waterfall phase transition of the standard hybrid inflation model is studied. We show that whether or not appreciable amounts of large scale curvature perturbations are produced during the waterfall phase transition depends crucially on the competition between the classical and the quantum mechanical backreactions to terminate inflation. If one considers only the classical evolution of the system, we show that the highly blue-tilted entropy perturbations induce highly blue-tilted large scale curvature perturbations during the waterfall phase transition which dominate over the original adiabatic curvature perturbations. However, we show that the quantum backreactions of the waterfall field inhomogeneities produced during the phase transition dominate completely over the classical backreactions. The cumulative quantum backreactions of very small scale tachyonic modes terminate inflation very efficiently and shut off the curvature perturbation evolution during the waterfall phase transition. This indicates that the standard hybrid inflation model is safe under large scale curvature perturbations during the waterfall phase transition.

  7. Comparative effectiveness of metal ions in inducing curvature of primary roots of Zea mays

    Science.gov (United States)

    Hasenstein, K. H.; Evans, M. L.; Stinemetz, C. L.; Moore, R.; Fondren, W. M.; Koon, E. C.; Higby, M. A.; Smucker, A. J.

    1988-01-01

    We used five cultivars of Zea mays (Bear Hybrid WF9 * 38MS, B73 * Missouri 17, Yellow Dent, Merit, and Great Lakes Hybrid 422) to reinvestigate the specificity of metal ions for inducing root curvature. Of 17 cations tested, 6 (Al3+, Ba2+, Ca2+, Cd2+, Cu2+, Zn2+) induced curvature. Roots curved away from Al3+, Ba2+, and Cd2+. Roots curved away from low (0.1 millimolar) concentrations of Cu2+ but toward higher (1-5 millimolar) concentrations. Roots initially curved away from Zn2+ but the direction of the subsequent curvature was unpredictable. In most cases, roots of all cultivars curved towards calcium. However, in some tests there was no response to calcium or even (especially in the cultivars Merit and B73 * Missouri 17) substantial curvature away from calcium. The results indicate that the induction of root curvature is not specific for calcium. The results are discussed relative to the possible role of calmodulin as a mediator of ion-induced root curvature.

  8. On the curvature of transmitted intensity plots in broad beam studies

    International Nuclear Information System (INIS)

    El-Kateb, A.H.

    2000-01-01

    Transmission of a broad beam of gamma rays of 81- and 356-keV energies from 133 Ba is studied singly and dually. This study is the first to deal with the curvatures of the intensity plots. The targets are dextrose solutions of percentage concentrations up to 0.125 and soil containing water with concentrations up to 0.319. The logarithmic intensity plots are expressed in terms of a polynomial in the concentration. The curvatures of the plots are measured and calculated on the basis of the theoretical mass attenuation coefficients. The results are discussed in conjunction with buildup factors and the probability of photoelectric and Compton interactions. The curvatures show maxima when incoherent interaction prevails. This is evidently proved in case of the single 356-keV and of the dual 81- and 356-keV applied energies. Comparison is performed between the measured and calculated curvatures. The concept of curvature is applied and discussed for published results of narrow beam geometry. Correspondingly, this is the first search to introduce curvature instead of buildup as a measure for transmitted collided photons

  9. A geometric construction of the Riemann scalar curvature in Regge calculus

    Science.gov (United States)

    McDonald, Jonathan R.; Miller, Warner A.

    2008-10-01

    The Riemann scalar curvature plays a central role in Einstein's geometric theory of gravity. We describe a new geometric construction of this scalar curvature invariant at an event (vertex) in a discrete spacetime geometry. This allows one to constructively measure the scalar curvature using only clocks and photons. Given recent interest in discrete pre-geometric models of quantum gravity, we believe is it ever so important to reconstruct the curvature scalar with respect to a finite number of communicating observers. This derivation makes use of a new fundamental lattice cell built from elements inherited from both the original simplicial (Delaunay) spacetime and its circumcentric dual (Voronoi) lattice. The orthogonality properties between these two lattices yield an expression for the vertex-based scalar curvature which is strikingly similar to the corresponding hinge-based expression in Regge calculus (deficit angle per unit Voronoi dual area). In particular, we show that the scalar curvature is simply a vertex-based weighted average of deficits per weighted average of dual areas.

  10. A geometric construction of the Riemann scalar curvature in Regge calculus

    International Nuclear Information System (INIS)

    McDonald, Jonathan R; Miller, Warner A

    2008-01-01

    The Riemann scalar curvature plays a central role in Einstein's geometric theory of gravity. We describe a new geometric construction of this scalar curvature invariant at an event (vertex) in a discrete spacetime geometry. This allows one to constructively measure the scalar curvature using only clocks and photons. Given recent interest in discrete pre-geometric models of quantum gravity, we believe is it ever so important to reconstruct the curvature scalar with respect to a finite number of communicating observers. This derivation makes use of a new fundamental lattice cell built from elements inherited from both the original simplicial (Delaunay) spacetime and its circumcentric dual (Voronoi) lattice. The orthogonality properties between these two lattices yield an expression for the vertex-based scalar curvature which is strikingly similar to the corresponding hinge-based expression in Regge calculus (deficit angle per unit Voronoi dual area). In particular, we show that the scalar curvature is simply a vertex-based weighted average of deficits per weighted average of dual areas

  11. Moment-Curvature Behaviors of Concrete Beams Singly Reinforced by Steel-FRP Composite Bars

    Directory of Open Access Journals (Sweden)

    Zeyang Sun

    2017-01-01

    Full Text Available A steel-fiber-reinforced polymer (FRP composite bar (SFCB is a kind of rebar with inner steel bar wrapped by FRP, which can achieve a better anticorrosion performance than that of ordinary steel bar. The high ultimate strength of FRP can also provide a significant increase in load bearing capacity. Based on the adequate simulation of the load-displacement behaviors of concrete beams reinforced by SFCBs, a parametric analysis of the moment-curvature behaviors of concrete beams that are singly reinforced by SFCB was conducted. The critical reinforcement ratio for differentiating the beam’s failure mode was presented, and the concept of the maximum possible peak curvature (MPPC was proposed. After the ultimate curvature reached MPPC, it decreased with an increase in the postyield stiffness ratio (rsf, and the theoretical calculation method about the curvatures before and after the MPPC was derived. The influence of the reinforcement ratio, effective depth, and FRP ultimate strain on the ultimate point was studied by the dimensionless moment and curvature. By calculating the envelope area under the moment-curvature curve, the energy ductility index can obtain a balance between the bearing capacity and the deformation ability. This paper can provide a reference for the design of concrete beams that are reinforced by SFCB or hybrid steel bar/FRP bar.

  12. Incorporating contact angles in the surface tension force with the ACES interface curvature scheme

    Science.gov (United States)

    Owkes, Mark

    2017-11-01

    In simulations of gas-liquid flows interacting with solid boundaries, the contact line dynamics effect the interface motion and flow field through the surface tension force. The surface tension force is directly proportional to the interface curvature and the problem of accurately imposing a contact angle must be incorporated into the interface curvature calculation. Many commonly used algorithms to compute interface curvatures (e.g., height function method) require extrapolating the interface, with defined contact angle, into the solid to allow for the calculation of a curvature near a wall. Extrapolating can be an ill-posed problem, especially in three-dimensions or when multiple contact lines are near each other. We have developed an accurate methodology to compute interface curvatures that allows for contact angles to be easily incorporated while avoiding extrapolation and the associated challenges. The method, known as Adjustable Curvature Evaluation Scale (ACES), leverages a least squares fit of a polynomial to points computed on the volume-of-fluid (VOF) representation of the gas-liquid interface. The method is tested by simulating canonical test cases and then applied to simulate the injection and motion of water droplets in a channel (relevant to PEM fuel cells).

  13. PREFERENCE, PRINCIPLE AND PRACTICE

    DEFF Research Database (Denmark)

    Skovsgaard, Morten; Bro, Peter

    2011-01-01

    Legitimacy has become a central issue in journalism, since the understanding of what journalism is and who journalists are has been challenged by developments both within and outside the newsrooms. Nonetheless, little scholarly work has been conducted to aid conceptual clarification as to how jou...... distinct, but interconnected categories*preference, principle, and practice. Through this framework, historical attempts to justify journalism and journalists are described and discussed in the light of the present challenges for the profession....

  14. Emotions and Economic Preference

    OpenAIRE

    Todorova, Tamara; Ramachandran, Bharath

    2005-01-01

    We wish to examine critically the viewpoint that: a) economists take too narrow a view of rationality and do not recognize the role of emotions as a component of rationality and b) do not address the question of whether preferences are rational or not, and instead take them as just given. We trace the relationship between economics and emotions showing some economic dimensions of emotional states. We illustrate them with examples of economic behavior based on emotional reactions.

  15. Two-component fluid membranes near repulsive walls: Linearized hydrodynamics of equilibrium and nonequilibrium states.

    Science.gov (United States)

    Sankararaman, Sumithra; Menon, Gautam I; Sunil Kumar, P B

    2002-09-01

    We study the linearized hydrodynamics of a two-component fluid membrane near a repulsive wall, using a model that incorporates curvature-concentration coupling as well as hydrodynamic interactions. This model is a simplified version of a recently proposed one [J.-B. Manneville et al., Phys. Rev. E 64, 021908 (2001)] for nonequilibrium force centers embedded in fluid membranes, such as light-activated bacteriorhodopsin pumps incorporated in phospholipid egg phosphatidyl choline (EPC) bilayers. The pump-membrane system is modeled as an impermeable, two-component bilayer fluid membrane in the presence of an ambient solvent, in which one component, representing active pumps, is described in terms of force dipoles displaced with respect to the bilayer midpoint. We first discuss the case in which such pumps are rendered inactive, computing the mode structure in the bulk as well as the modification of hydrodynamic properties by the presence of a nearby wall. These results should apply, more generally, to equilibrium fluid membranes comprised of two components, in which the effects of curvature-concentration coupling are significant, above the threshold for phase separation. We then discuss the fluctuations and mode structure in the steady state of active two-component membranes near a repulsive wall. We find that proximity to the wall smoothens membrane height fluctuations in the stable regime, resulting in a logarithmic scaling of the roughness even for initially tensionless membranes. This explicitly nonequilibrium result is a consequence of the incorporation of curvature-concentration coupling in our hydrodynamic treatment. This result also indicates that earlier scaling arguments which obtained an increase in the roughness of active membranes near repulsive walls upon neglecting the role played by such couplings may need to be reevaluated.

  16. G protein-membrane interactions II: Effect of G protein-linked lipids on membrane structure and G protein-membrane interactions.

    Science.gov (United States)

    Casas, Jesús; Ibarguren, Maitane; Álvarez, Rafael; Terés, Silvia; Lladó, Victoria; Piotto, Stefano P; Concilio, Simona; Busquets, Xavier; López, David J; Escribá, Pablo V

    2017-09-01

    G proteins often bear myristoyl, palmitoyl and isoprenyl moieties, which favor their association with the membrane and their accumulation in G Protein Coupled Receptor-rich microdomains. These lipids influence the biophysical properties of membranes and thereby modulate G protein binding to bilayers. In this context, we showed here that geranylgeraniol, but neither myristate nor palmitate, increased the inverted hexagonal (H II ) phase propensity of phosphatidylethanolamine-containing membranes. While myristate and palmitate preferentially associated with phosphatidylcholine membranes, geranylgeraniol favored nonlamellar-prone membranes. In addition, Gαi 1 monomers had a higher affinity for lamellar phases, while Gβγ and Gαβγ showed a marked preference for nonlamellar prone membranes. Moreover, geranylgeraniol enhanced the binding of G protein dimers and trimers to phosphatidylethanolamine-containing membranes, yet it decreased that of monomers. By contrast, both myristate and palmitate increased the Gαi 1 preference for lamellar membranes. Palmitoylation reinforced the binding of the monomer to PC membranes and myristoylation decreased its binding to PE-enriched bilayer. Finally, binding of dimers and trimers to lamellar-prone membranes was decreased by palmitate and myristate, but it was increased in nonlamellar-prone bilayers. These results demonstrate that co/post-translational G protein lipid modifications regulate the membrane lipid structure and that they influence the physico-chemical properties of membranes, which in part explains why G protein subunits sort to different plasma membrane domains. This article is part of a Special Issue entitled: Membrane Lipid Therapy: Drugs Targeting Biomembranes edited by Pablo V. Escribá. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Solid polymer electrolyte composite membrane comprising laser micromachined porous support

    Science.gov (United States)

    Liu, Han [Waltham, MA; LaConti, Anthony B [Lynnfield, MA; Mittelsteadt, Cortney K [Natick, MA; McCallum, Thomas J [Ashland, MA

    2011-01-11

    A solid polymer electrolyte composite membrane and method of manufacturing the same. According to one embodiment, the composite membrane comprises a rigid, non-electrically-conducting support, the support preferably being a sheet of polyimide having a thickness of about 7.5 to 15 microns. The support has a plurality of cylindrical pores extending perpendicularly between opposing top and bottom surfaces of the support. The pores, which preferably have a diameter of about 5 microns, are made by laser micromachining and preferably are arranged in a defined pattern, for example, with fewer pores located in areas of high membrane stress and more pores located in areas of low membrane stress. The pores are filled with a first solid polymer electrolyte, such as a perfluorosulfonic acid (PFSA) polymer. A second solid polymer electrolyte, which may be the same as or different than the first solid polymer electrolyte, may be deposited over the top and/or bottom of the first solid polymer electrolyte.

  18. The Vocational Preference Inventory Scores and Environmental Preferences

    Science.gov (United States)

    Kunce, Joseph T.; Kappes, Bruno Maurice

    1976-01-01

    This study investigated the relationship between vocational interest measured by the Vocational Preference Inventory (VPI) and preferences of 175 undergraduates for structured or unstructured environments. Males having clear-cut preferences for structured situations had significantly higher Realistic-Conventional scores than those without…

  19. Robotic membranes

    DEFF Research Database (Denmark)

    Ramsgaard Thomsen, Mette

    2008-01-01

    The relationship between digital and analogue is often constructed as one of opposition. The perception that the world is permeated with underlying patterns of data, describing events and matter alike, suggests that information can be understood apart from the substance to which it is associated......, and that its encoded logic can be constructed and reconfigured as an isolated entity. This disembodiment of information from materiality implies that an event like a thunderstorm, or a material like a body, can be described equally by data, in other words it can be read or written. The following prototypes......, Vivisection and Strange Metabolisms, were developed at the Centre for Information Technology and Architecture (CITA) at the Royal Danish Academy of Fine Arts in Copenhagen as a means of engaging intangible digital data with tactile physical material. As robotic membranes, they are a dual examination...

  20. The Causes of Preference Reversal.

    OpenAIRE

    Tversky, Amos; Slovic, Paul; Kahneman, Daniel

    1990-01-01

    Observed preference reversal cannot be adequately explained by violations of independence, the reduction axiom, or transitivity. The primary cause of preference reversal is the failure of procedure invariance, especially the overpricing of low-probability, high-payoff bets. This result violates regret theory and generalized (nonindependent) utility models. Preference reversal and a new reversal involving time preferences are explained by scale compatibility, which implies that payoffs are wei...

  1. Human preference for air movement

    DEFF Research Database (Denmark)

    Toftum, Jørn; Melikov, Arsen Krikor; Tynel, A.

    2002-01-01

    Human preference for air movement was studied at slightly cool, neutral, and slightly warm overall thermal sensations and at temperatures ranging from 18 deg.C to 28 deg.C. Air movement preference depended on both thermal sensation and temperature, but large inter-individual differences existed...... between subjects. Preference for less air movement was linearly correlated with draught discomfort, but the percentage of subjects who felt draught was lower than the percentage who preferred less air movement....

  2. Membrane contactor/separator for an advanced ozone membrane reactor for treatment of recalcitrant organic pollutants in water

    International Nuclear Information System (INIS)

    Chan, Wai Kit; Jouët, Justine; Heng, Samuel; Yeung, King Lun; Schrotter, Jean-Christophe

    2012-01-01

    An advanced ozone membrane reactor that synergistically combines membrane distributor for ozone gas, membrane contactor for pollutant adsorption and reaction, and membrane separator for clean water production is described. The membrane reactor represents an order of magnitude improvement over traditional semibatch reactor design and is capable of complete conversion of recalcitrant endocrine disrupting compounds (EDCs) in water at less than three minutes residence time. Coating the membrane contactor with alumina and hydrotalcite (Mg/Al=3) adsorbs and traps the organics in the reaction zone resulting in 30% increase of total organic carbon (TOC) removal. Large surface area coating that diffuses surface charges from adsorbed polar organic molecules is preferred as it reduces membrane polarization that is detrimental to separation. - Graphical abstract: Advanced ozone membrane reactor synergistically combines membrane distributor for ozone, membrane contactor for sorption and reaction and membrane separator for clean water production to achieve an order of magnitude enhancement in treatment performance compared to traditional ozone reactor. Highlights: ► Novel reactor using membranes for ozone distributor, reaction contactor and water separator. ► Designed to achieve an order of magnitude enhancement over traditional reactor. ► Al 2 O 3 and hydrotalcite coatings capture and trap pollutants giving additional 30% TOC removal. ► High surface area coating prevents polarization and improves membrane separation and life.

  3. Correlations between gravitropic curvature and auxin movement across gravistimulated roots of Zea mays

    Science.gov (United States)

    Young, L. M.; Evans, M. L.; Hertel, R.

    1990-01-01

    We compared the kinetics of auxin redistribution across the caps of primary roots of 2-day-old maize (Zea mays, cv Merit) seedlings with the time course of gravitropic curvature. [3H] indoleacetic acid was applied to one side of the cap in an agar donor and radioactivity moving across the cap was collected in an agar receiver applied to the opposite side. Upon gravistimulation the roots first curved upward slightly, then returned to the horizontal and began curving downward, reaching a final angle of about 67 degrees. Movement of label across the caps of gravistimulated roots was asymmetric with preferential downward movement (ratio downward/upward = ca. 1.6, radioactivity collected during the 90 min following beginning of gravistimulation). There was a close correlation between the development of asymmetric auxin movement across the root cap and the rate of curvature, with both values increasing to a maximum and then declining as the roots approached the final angle of curvature. In roots preadapted to gravity (alternate brief stimulation on opposite flanks over a period of 1 hour) the initial phase of upward curvature was eliminated and downward bending began earlier than for controls. The correlation between asymmetric auxin movement and the kinetics of curvature also held in comparisons between control and preadapted roots. Both downward auxin transport asymmetry and downward curvature occurred earlier in preadapted roots than in controls. These findings are consistent with suggestions that the root cap is not only the site of perception but also the location of the initial redistribution of effectors that ultimately leads to curvature.

  4. Effects of ethylene on the kinetics of curvature and auxin redistribution in gravistimulated roots of Zea mays

    Science.gov (United States)

    Lee, J. S.; Evans, M. L.

    1990-01-01

    We tested the involvement of ethylene in maize (Zea mays L.) root gravitropism by measuring the kinetics of curvature and lateral auxin movement in roots treated with ethylene, inhibitors of ethylene synthesis, or inhibitors of ethylene action. In the presence of ethylene the latent period of gravitropic curvature appeared to be increased somewhat. However, ethylene-treated roots continued to curve after control roots had reached their final angle of curvature. Consequently, maximum curvature in the presence of ethylene was much greater in ethylene-treated roots than in controls. Inhibitors of ethylene biosynthesis or action had effects on the kinetics of curvature opposite to that of ethylene, i.e. the latent period appeared to be shortened somewhat while total curvature was reduced relative to that of controls. Label from applied 3H-indole-3-acetic acid was preferentially transported toward the lower side of stimulated roots. In parallel with effects on curvature, ethylene treatment delayed the development of gravity-induced asymmetric auxin movement across the root but extended its duration once initiated. The auxin transport inhibitor, 1-N-naphthylphthalamic acid reduced both gravitropic curvature and the effect of ethylene on curvature. Since neither ethylene nor inhibitors of ethylene biosynthesis or action prevented curvature, we conclude that ethylene does not mediate the primary differential growth response causing curvature. Because ethylene affects curvature and auxin transport in parallel, we suggest that ethylene modifies curvature by affecting gravity-induced lateral transport of auxin, perhaps by interfering with adaptation of the auxin transport system to the gravistimulus.

  5. Organizing membrane-curving proteins: the emerging dynamical picture.

    Science.gov (United States)

    Simunovic, Mijo; Bassereau, Patricia; Voth, Gregory A

    2018-03-30

    Lipid membranes play key roles in cells, such as in trafficking, division, infection, remodeling of organelles, among others. The key step in all these processes is creating membrane curvature, typically under the control of many anchored, adhered or included proteins. However, it has become clear that the membrane itself can mediate the interactions among proteins to produce highly ordered assemblies. Computer simulations are ideally suited to investigate protein organization and the dynamics of membrane remodeling at near-micron scales, something that is extremely challenging to tackle experimentally. We review recent computational efforts in modeling protein-caused membrane deformation mechanisms, specifically focusing on coarse-grained simulations. We highlight work that exposed the membrane-mediated ordering of proteins into lines, meshwork, spirals and other assemblies, in what seems to be a very generic mechanism driven by a combination of short and long-ranged forces. Modulating the mechanical properties of membranes is an underexplored signaling mechanism in various processes deserving of more attention in the near future. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Treatment preference in hypochondriasis.

    Science.gov (United States)

    Walker, J; Vincent, N; Furer, P; Cox, B; Kjernisted, K

    1999-12-01

    Promising cognitive-behavioral and medication treatments for hypochondriasis are in the early stages of evaluation. Little is known about the treatment preferences and opinions of individuals seeking help for this problem. In this exploratory study, 23 volunteers from the community with a DSM-IV diagnosis of hypochondriasis were recruited through a newspaper advertisement. Participants were presented with a survey which included balanced descriptions of both a medication and a cognitive-behavioral treatment for intense illness concerns (hypochondriasis). The brief descriptions of the treatments discussed the time commitment required as well as the major advantages and disadvantages of each. Results showed that, relative to medication treatment, cognitive-behavioral treatment was predicted to be more effective in both the short and long terms and was rated as more acceptable. Psychological treatment was indicated as the first choice by 74% of respondents, medication by 4%, and 22% indicated an equal preference. Forty-eight percent of respondents would only accept the psychological treatment.

  7. Estimating exponential scheduling preferences

    DEFF Research Database (Denmark)

    Hjorth, Katrine; Börjesson, Maria; Engelson, Leonid

    Extended abstract Choice of departure time is a travel choice dimension that transportation planners often need to forecast in appraisal. A traveller may shift departure time in response to changes in expected travel time or travel time variability (TTV) or in response to time-differentiated cong......Extended abstract Choice of departure time is a travel choice dimension that transportation planners often need to forecast in appraisal. A traveller may shift departure time in response to changes in expected travel time or travel time variability (TTV) or in response to time...... from the underlying scheduling preferences (Noland and Small, 1995, Bates et al., 2001, Fosgerau and Karlström, 2010). The scheduling preferences can be formally represented as time-dependent rates of utility derived at different locations. Assuming that the travellers are rational and choose departure......’ departure time choice. The assumption underlying the scheduling approach is that the traveller rationally maximises her total utility obtained during a period of time. The total utility depends on time of departure from the origin and time of arrival to the destination. The total utility is usually assumed...

  8. Membrane invagination induced by Shiga toxin B-subunit

    DEFF Research Database (Denmark)

    Pezeshkian, W.; Hansen, Allan Grønhøj; Johannes, Ludger

    2016-01-01

    -atom molecular dynamics and Monte Carlo simulations we show that the molecular architecture of STxB enables the following sequence of events: the Gb3 binding sites on STxB are arranged such that tight avidity-based binding results in a small increment of local curvature. Membrane-mediated clustering of several...... toxin molecules then creates a tubular membrane invagination that drives toxin entry into the cell. This mechanism requires: (1) a precise molecular architecture of the STxB binding sites; (2) a fluid bilayer in order for the tubular invagination to form. Although, STxB binding to the membrane requires...... specific interactions with Gb3 lipids, our study points to a generic molecular design principle for clathrin-independent endocytosis of nanoparticles....

  9. Probing cellular behaviors through nanopatterned chitosan membranes

    International Nuclear Information System (INIS)

    Yang, Chung-Yao; Sung, Chun-Yen; Shuai, Hung-Hsun; Cheng, Chao-Min; Yeh, J Andrew

    2013-01-01

    This paper describes a high-throughput method for developing physically modified chitosan membranes to probe the cellular behavior of MDCK epithelial cells and HIG-82 fibroblasts adhered onto these modified membranes. To prepare chitosan membranes with micro/nanoscaled features, we have demonstrated an easy-to-handle, facile approach that could be easily integrated with IC-based manufacturing processes with mass production potential. These physically modified chitosan membranes were observed by scanning electron microscopy to gain a better understanding of chitosan membrane surface morphology. After MDCK cells and HIG-82 fibroblasts were cultured on these modified chitosan membranes for various culture durations (i.e. 1, 2, 4, 12 and 24 h), they were investigated to decipher cellular behavior. We found that both cells preferred to adhere onto a flat surface rather than on a nanopatterned surface. However, most (> 80%) of the MDCK cells showed rounded morphology and would suspend in the cultured medium instead of adhering onto the planar surface of negatively nanopatterned chitosan membranes. This means different cell types (e.g. fibroblasts versus epithelia) showed distinct capabilities/preferences of adherence for materials of varying surface roughness. We also showed that chitosan membranes could be re-used at least nine times without significant contamination and would provide us consistency for probing cell–material interactions by permitting reuse of the same substrate. We believe these results would provide us better insight into cellular behavior, specifically, microscopic properties and characteristics of cells grown under unique, nanopatterned cell-interface conditions. (paper)

  10. Membrane morphology is actively transformed by covalent binding of the protein Atg8 to PE-lipids.

    Directory of Open Access Journals (Sweden)

    Roland L Knorr

    Full Text Available Autophagy is a cellular degradation pathway involving the shape transformation of lipid bilayers. During the onset of autophagy, the water-soluble protein Atg8 binds covalently to phosphatdylethanolamines (PEs in the membrane in an ubiquitin-like reaction coupled to ATP hydrolysis. We reconstituted the Atg8 conjugation system in giant and nm-sized vesicles with a minimal set of enzymes and observed that formation of Atg8-PE on giant vesicles can cause substantial tubulation of membranes even in the absence of Atg12-Atg5-Atg16. Our findings show that ubiquitin-like processes can actively change properties of lipid membranes and that membrane crowding by proteins can be dynamically regulated in cells. Furthermore we provide evidence for curvature sorting of Atg8-PE. Curvature generation and sorting are directly linked to organelle shapes and, thus, to biological function. Our results suggest that a positive feedback exists between the ubiquitin-like reaction and the membrane curvature, which is important for dynamic shape changes of cell membranes, such as those involved in the formation of autophagosomes.

  11. Anatomical study of the radius and center of curvature of the distal femoral condyle

    KAUST Repository

    Kosel, Jü rgen; Giouroudi, Ioanna; Scheffer, Cornie; Dillon, Edwin Mark; Erasmus, Pieter J.

    2010-01-01

    In this anatomical study, the anteroposterior curvature of the surface of 16 cadaveric distal femurs was examined in terms of radii and center point. Those two parameters attract high interest due to their significance for total knee arthroplasty. Basically, two different conclusions have been drawn in foregoing studies: (1) The curvature shows a constant radius and (2) the curvature shows a variable radius. The investigations were based on a new method combining three-dimensional laser-scanning and planar geometrical analyses. This method is aimed at providing high accuracy and high local resolution. The high-precision laser scanning enables the exact reproduction of the distal femurs - including their cartilage tissue - as a three-dimensional computer model. The surface curvature was investigated on intersection planes that were oriented perpendicularly to the surgical epicondylar line. Three planes were placed at the central part of each condyle. The intersection of either plane with the femur model was approximated with the help of a b-spline, yielding three b-splines on each condyle. The radii and center points of the circles, approximating the local curvature of the b-splines, were then evaluated. The results from all three b-splines were averaged in order to increase the reliability of the method. The results show the variation in the surface curvatures of the investigated samples of condyles. These variations are expressed in the pattern of the center points and the radii of the curvatures. The standard deviations of the radii for a 90 deg arc on the posterior condyle range from 0.6 mm up to 5.1 mm, with an average of 2.4 mm laterally and 2.2 mm medially. No correlation was found between the curvature of the lateral and medial condyles. Within the range of the investigated 16 samples, the conclusion can be drawn that the condyle surface curvature is not constant and different for all specimens when viewed along the surgical epicondylar axis. For the portion

  12. Regional surface geometry of the rat stomach based on three-dimensional curvature analysis

    Energy Technology Data Exchange (ETDEWEB)

    Liao Donghua [Center of Excellence in Visceral Biomechanics and Pain, Aalborg Hospital, DK-9100 Aalborg (Denmark); Zhao Jingbo [Center of Excellence in Visceral Biomechanics and Pain, Aalborg Hospital, DK-9100 Aalborg (Denmark); Gregersen, Hans [Center of Excellence in Visceral Biomechanics and Pain, Aalborg Hospital, DK-9100 Aalborg (Denmark)

    2005-01-21

    A better understanding of gastric accommodation and gastric perception requires knowledge of regional gastric geometry and local gastric tension throughout the stomach. An analytic method based on medical imaging data was developed in this study to describe the three-dimensional (3D) rat stomach geometry and tension distribution. The surface principal radii of curvatures were simulated and the surface tension was calculated in the glandular and non-glandular region of the stomach at pressures from 0 Pa to 800 Pa. The radii of curvature and tension distribution in the stomach were non-homogeneous. The radii of curvature in the glandular stomach were larger than those in the non-glandular region at pressures less than 100 Pa (P < 0.001). When the pressure increased to more than 200 Pa, the radii of curvature in the non-glandular stomach was larger than in the glandular stomach (P < 0.05). The curvature and tension distribution mapping using medical imaging technology and 3D models can be used to characterize and distinguish the physical behaviour in separate regions of the stomach.

  13. Regional surface geometry of the rat stomach based on three-dimensional curvature analysis

    International Nuclear Information System (INIS)

    Liao Donghua; Zhao Jingbo; Gregersen, Hans

    2005-01-01

    A better understanding of gastric accommodation and gastric perception requires knowledge of regional gastric geometry and local gastric tension throughout the stomach. An analytic method based on medical imaging data was developed in this study to describe the three-dimensional (3D) rat stomach geometry and tension distribution. The surface principal radii of curvatures were simulated and the surface tension was calculated in the glandular and non-glandular region of the stomach at pressures from 0 Pa to 800 Pa. The radii of curvature and tension distribution in the stomach were non-homogeneous. The radii of curvature in the glandular stomach were larger than those in the non-glandular region at pressures less than 100 Pa (P < 0.001). When the pressure increased to more than 200 Pa, the radii of curvature in the non-glandular stomach was larger than in the glandular stomach (P < 0.05). The curvature and tension distribution mapping using medical imaging technology and 3D models can be used to characterize and distinguish the physical behaviour in separate regions of the stomach

  14. The geometric curvature of the lumbar spine during restricted and unrestricted squats.

    Science.gov (United States)

    Hebling Campos, Mário; Furtado Alaman, Laizi I; Seffrin-Neto, Aldo A; Vieira, Carlos A; Costa de Paula, Marcelo; Barbosa de Lira, Claudio A

    2017-06-01

    The main purpose of this study was to analyze the behavior of the geometric curvature of the lumbar spine during restricted and unrestricted squats, using a novel investigative method. The rationale for our hypothesis is that the lumbar curvature has different patterns at different spine levels depending on the squat technique used. Spine motion was collected via stereo-photogrammetric analysis in nineteen participants (11 males, 8 females). The reconstructed spine points at the upright neutral position and at the deepest position of the squat exercise were projected onto the sagittal plane of the trunk, a polynomial was fitted to the data, and were quantified the two-dimensional geometric curvature at lower, central and higher lumbar levels, besides the inclination of trunk and lumbosacral region, the overall geometric curvature and overall angle of the lumbar spine. The mean values for each variable were analysed with paired t-test (Psquat techniques and these effects are also reduced in unrestricted squats. The data collected in the study are evidence that during barbell squats the lumbar curvature has different patterns at different spinal levels depending on the exercise technique. The lower lumbar spine appears to be less overloaded during unrestricted squats.

  15. Four-Spacecraft Magnetic Curvature and Vorticity Analyses on Kelvin-Helmholtz Waves in MHD Simulations

    Science.gov (United States)

    Kieokaew, Rungployphan; Foullon, Claire; Lavraud, Benoit

    2018-01-01

    Four-spacecraft missions are probing the Earth's magnetospheric environment with high potential for revealing spatial and temporal scales of a variety of in situ phenomena. The techniques allowed by these four spacecraft include the calculation of vorticity and the magnetic curvature analysis (MCA), both of which have been used in the study of various plasma structures. Motivated by curved magnetic field and vortical structures induced by Kelvin- Helmholtz (KH) waves, we investigate the robustness of the MCA and vorticity techniques when increasing (regular) tetrahedron sizes, to interpret real data. Here for the first time, we test both techniques on a 2.5-D MHD simulation of KH waves at the magnetopause. We investigate, in particular, the curvature and flow vorticity across KH vortices and produce time series for static spacecraft in the boundary layers. The combined results of magnetic curvature and vorticity further help us to understand the development of KH waves. In particular, first, in the trailing edge, the magnetic curvature across the magnetopause points in opposite directions, in the wave propagation direction on the magnetosheath side and against it on the magnetospheric side. Second, the existence of a "turnover layer" in the magnetospheric side, defined by negative vorticity for the duskside magnetopause, which persists in the saturation phase, is reminiscent of roll-up history. We found significant variations in the MCA measures depending on the size of the tetrahedron. This study lends support for cross-scale observations to better understand the nature of curvature and its role in plasma phenomena.

  16. Awareness Becomes Necessary Between Adaptive Pattern Coding of Open and Closed Curvatures

    Science.gov (United States)

    Sweeny, Timothy D.; Grabowecky, Marcia; Suzuki, Satoru

    2012-01-01

    Visual pattern processing becomes increasingly complex along the ventral pathway, from the low-level coding of local orientation in the primary visual cortex to the high-level coding of face identity in temporal visual areas. Previous research using pattern aftereffects as a psychophysical tool to measure activation of adaptive feature coding has suggested that awareness is relatively unimportant for the coding of orientation, but awareness is crucial for the coding of face identity. We investigated where along the ventral visual pathway awareness becomes crucial for pattern coding. Monoptic masking, which interferes with neural spiking activity in low-level processing while preserving awareness of the adaptor, eliminated open-curvature aftereffects but preserved closed-curvature aftereffects. In contrast, dichoptic masking, which spares spiking activity in low-level processing while wiping out awareness, preserved open-curvature aftereffects but eliminated closed-curvature aftereffects. This double dissociation suggests that adaptive coding of open and closed curvatures straddles the divide between weakly and strongly awareness-dependent pattern coding. PMID:21690314

  17. Experimental study of curvature effects on jet impingement heat transfer on concave surfaces

    Directory of Open Access Journals (Sweden)

    Ying Zhou

    2017-04-01

    Full Text Available Experimental study of the local and average heat transfer characteristics of a single round jet impinging on the concave surfaces was conducted in this work to gain in-depth knowledge of the curvature effects. The experiments were conducted by employing a piccolo tube with one single jet hole over a wide range of parameters: jet Reynolds number from 27000 to 130000, relative nozzle to surface distance from 3.3 to 30, and relative surface curvature from 0.005 to 0.030. Experimental results indicate that the surface curvature has opposite effects on heat transfer characteristics. On one hand, an increase of relative nozzle to surface distance (increasing jet diameter in fact enhances the average heat transfer around the surface for the same curved surface. On the other hand, the average Nusselt number decreases as relative nozzle to surface distance increases for a fixed jet diameter. Finally, experimental data-based correlations of the average Nusselt number over the curved surface were obtained with consideration of surface curvature effect. This work contributes to a better understanding of the curvature effects on heat transfer of a round jet impingement on concave surfaces, which is of high importance to the design of the aircraft anti-icing system.

  18. Ocular dimensions, corneal thickness, and corneal curvature in quarter horses with hereditary equine regional dermal asthenia.

    Science.gov (United States)

    Badial, Peres R; Cisneros-Àlvarez, Luis Emiliano; Brandão, Cláudia Valéria S; Ranzani, José Joaquim T; Tomaz, Mayana A R V; Machado, Vania M; Borges, Alexandre S

    2015-09-01

    The aim of this study was to compare ocular dimensions, corneal curvature, and corneal thickness between horses affected with hereditary equine regional dermal asthenia (HERDA) and unaffected horses. Five HERDA-affected quarter horses and five healthy control quarter horses were used. Schirmer's tear test, tonometry, and corneal diameter measurements were performed in both eyes of all horses prior to ophthalmologic examinations. Ultrasonic pachymetry was performed to measure the central, temporal, nasal, dorsal, and ventral corneal thicknesses in all horses. B-mode ultrasound scanning was performed on both eyes of each horse to determine the dimensions of the ocular structures and to calculate the corneal curvature. Each corneal region examined in this study was thinner in the affected group compared with the healthy control group. However, significant differences in corneal thickness were only observed for the central and dorsal regions. HERDA-affected horses exhibited significant increases in corneal curvature and corneal diameter compared with unaffected animals. The ophthalmologic examinations revealed mild corneal opacity in one eye of one affected horse and in both eyes of three affected horses. No significant between-group differences were observed for Schirmer's tear test, intraocular pressure, or ocular dimensions. Hereditary equine regional dermal asthenia-affected horses exhibit decreased corneal thickness in several regions of the cornea, increased corneal curvature, increased corneal diameter, and mild corneal opacity. Additional research is required to determine whether the increased corneal curvature significantly impacts the visual accuracy of horses with HERDA. © 2014 American College of Veterinary Ophthalmologists.

  19. Adjuvant Maneuvers for Residual Curvature Correction During Penile Prosthesis Implantation in Men with Peyronie's Disease.

    Science.gov (United States)

    Berookhim, Boback M; Karpman, Edward; Carrion, Rafael

    2015-11-01

    The surgical treatment of comorbid erectile dysfunction and Peyronie's disease has long included the implantation of an inflatable penile prosthesis as well as a number of adjuvant maneuvers to address residual curvature after prosthesis placement. To review the various surgical options for addressing curvature after prosthesis placement, with specific attention paid to an original article by Wilson et al. reporting on modeling over a penile prosthesis for the management of Peyronie's disease. A literature review was performed analyzing articles reporting the management of penile curvature in patients undergoing implantation of an inflatable penile prosthesis. Reported improvement in Peyronie's deformity as well as the complication rate associated with the various surgical techniques described. Modeling is a well-established treatment modality among patients with Peyronie's disease undergoing penile prosthesis implantation. A variety of other adjuvant maneuvers to address residual curvature when modeling alone is insufficient has been presented in the literature. Over 20 years of experience with modeling over a penile prosthesis have proven the efficacy and safety of this treatment option, providing the surgeon a simple initial step for the management of residual curvature after penile implantation which allows for the use of additional adjuvant maneuvers in those with significant deformities. © 2015 International Society for Sexual Medicine.

  20. Scalar curvature in conformal geometry of Connes-Landi noncommutative manifolds

    Science.gov (United States)

    Liu, Yang

    2017-11-01

    We first propose a conformal geometry for Connes-Landi noncommutative manifolds and study the associated scalar curvature. The new scalar curvature contains its Riemannian counterpart as the commutative limit. Similar to the results on noncommutative two tori, the quantum part of the curvature consists of actions of the modular derivation through two local curvature functions. Explicit expressions for those functions are obtained for all even dimensions (greater than two). In dimension four, the one variable function shows striking similarity to the analytic functions of the characteristic classes appeared in the Atiyah-Singer local index formula, namely, it is roughly a product of the j-function (which defines the A ˆ -class of a manifold) and an exponential function (which defines the Chern character of a bundle). By performing two different computations for the variation of the Einstein-Hilbert action, we obtain deep internal relations between two local curvature functions. Straightforward verification for those relations gives a strong conceptual confirmation for the whole computational machinery we have developed so far, especially the Mathematica code hidden behind the paper.