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Sample records for member fun30 promotes

  1. The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci.

    Directory of Open Access Journals (Sweden)

    Ana Neves-Costa

    2009-12-01

    Full Text Available Chromatin regulates many key processes in the nucleus by controlling access to the underlying DNA. SNF2-like factors are ATP-driven enzymes that play key roles in the dynamics of chromatin by remodelling nucleosomes and other nucleoprotein complexes. Even simple eukaryotes such as yeast contain members of several subfamilies of SNF2-like factors. The FUN30/ETL1 subfamily of SNF2 remodellers is conserved from yeasts to humans, but is poorly characterized. We show that the deletion of FUN30 leads to sensitivity to the topoisomerase I poison camptothecin and to severe cell cycle progression defects when the Orc5 subunit is mutated. We demonstrate a role of FUN30 in promoting silencing in the heterochromatin-like mating type locus HMR, telomeres and the rDNA repeats. Chromatin immunoprecipitation experiments demonstrate that Fun30 binds at the boundary element of the silent HMR and within the silent HMR. Mapping of nucleosomes in vivo using micrococcal nuclease demonstrates that deletion of FUN30 leads to changes of the chromatin structure at the boundary element. A point mutation in the ATP-binding site abrogates the silencing function of Fun30 as well as its toxicity upon overexpression, indicating that the ATPase activity is essential for these roles of Fun30. We identify by amino acid sequence analysis a putative CUE motif as a feature of FUN30/ETL1 factors and show that this motif assists Fun30 activity. Our work suggests that Fun30 is directly involved in silencing by regulating the chromatin structure within or around silent loci.

  2. SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae.

    Directory of Open Access Journals (Sweden)

    Mickaël Durand-Dubief

    2012-09-01

    Full Text Available Budding yeast centromeres are sequence-defined point centromeres and are, unlike in many other organisms, not embedded in heterochromatin. Here we show that Fun30, a poorly understood SWI/SNF-like chromatin remodeling factor conserved in humans, promotes point centromere function through the formation of correct chromatin architecture at centromeres. Our determination of the genome-wide binding and nucleosome positioning properties of Fun30 shows that this enzyme is consistently enriched over centromeres and that a majority of CENs show Fun30-dependent changes in flanking nucleosome position and/or CEN core micrococcal nuclease accessibility. Fun30 deletion leads to defects in histone variant Htz1 occupancy genome-wide, including at and around most centromeres. FUN30 genetically interacts with CSE4, coding for the centromere-specific variant of histone H3, and counteracts the detrimental effect of transcription through centromeres on chromosome segregation and suppresses transcriptional noise over centromere CEN3. Previous work has shown a requirement for fission yeast and mammalian homologs of Fun30 in heterochromatin assembly. As centromeres in budding yeast are not embedded in heterochromatin, our findings indicate a direct role of Fun30 in centromere chromatin by promoting correct chromatin architecture.

  3. It's fun to transcribe with Fun30: A model for nucleosome dynamics during RNA polymerase II-mediated elongation.

    Science.gov (United States)

    Lee, Junwoo; Choi, Eun Shik; Lee, Daeyoup

    2018-01-01

    The ability of elongating RNA polymerase II (RNAPII) to regulate the nucleosome barrier is poorly understood because we do not know enough about the involved factors and we lack a conceptual framework to model this process. Our group recently identified the conserved Fun30/SMARCAD1 family chromatin-remodeling factor, Fun30 Fft3 , as being critical for relieving the nucleosome barrier during RNAPII-mediated elongation, and proposed a model illustrating how Fun30 Fft3 may contribute to nucleosome disassembly during RNAPII-mediated elongation. Here, we present a model that describes nucleosome dynamics during RNAPII-mediated elongation in mathematical terms and addresses the involvement of Fun30 Fft3 in this process.

  4. FunCoup 3.0: database of genome-wide functional coupling networks.

    Science.gov (United States)

    Schmitt, Thomas; Ogris, Christoph; Sonnhammer, Erik L L

    2014-01-01

    We present an update of the FunCoup database (http://FunCoup.sbc.su.se) of functional couplings, or functional associations, between genes and gene products. Identifying these functional couplings is an important step in the understanding of higher level mechanisms performed by complex cellular processes. FunCoup distinguishes between four classes of couplings: participation in the same signaling cascade, participation in the same metabolic process, co-membership in a protein complex and physical interaction. For each of these four classes, several types of experimental and statistical evidence are combined by Bayesian integration to predict genome-wide functional coupling networks. The FunCoup framework has been completely re-implemented to allow for more frequent future updates. It contains many improvements, such as a regularization procedure to automatically downweight redundant evidences and a novel method to incorporate phylogenetic profile similarity. Several datasets have been updated and new data have been added in FunCoup 3.0. Furthermore, we have developed a new Web site, which provides powerful tools to explore the predicted networks and to retrieve detailed information about the data underlying each prediction.

  5. Efficacy of the Fun For Wellness Online Intervention to Promote Well-Being Actions: A Secondary Data Analysis.

    Science.gov (United States)

    Myers, Nicholas D; Dietz, Samantha; Prilleltensky, Isaac; Prilleltensky, Ora; McMahon, Adam; Rubenstein, Carolyn L; Lee, Seungmin

    2018-04-30

    Fun For Wellness (FFW) is a new online intervention designed to promote growth in well-being by providing capability-enhancing learning opportunities (e.g., play an interactive game) to participants. The purpose of this study was to provide an initial evaluation of the efficacy of the FFW intervention to increase well-being actions. The study design was a secondary data analysis of a large-scale prospective, double-blind, parallel-group randomized controlled trial. Data were collected at baseline and 30 and 60 days postbaseline. A total of 479 adult employees at a major university in the southeast of the United States of America were enrolled. Participants who were randomly assigned to the FFW group were provided with 30 days of 24-hour access to the intervention. A two-class linear regression model with complier average causal effect estimation was fitted to well-being actions scores at 30 and 60 days. Intent-to-treat analysis provided evidence that the effect of being assigned to the FFW intervention, without considering actual participation in the FFW intervention, had a null effect on each dimension of well-being actions at 30 and 60 days. Participants who complied with the FFW intervention, however, had significantly higher well-being actions scores, compared to potential compliers in the Usual Care group, in the interpersonal dimension at 60 days, and the physical dimension at 30 days. Results from this secondary data analysis provide some supportive evidence for both the efficacy of and possible revisions to the FFW intervention in regard to promoting well-being actions.

  6. Efficacy of the Fun For Wellness Online Intervention to Promote Multidimensional Well-Being: a Randomized Controlled Trial.

    Science.gov (United States)

    Myers, Nicholas D; Prilleltensky, Isaac; Prilleltensky, Ora; McMahon, Adam; Dietz, Samantha; Rubenstein, Carolyn L

    2017-11-01

    Subjective well-being refers to people's level of satisfaction with life as a whole and with multiple dimensions within it. Interventions that promote subjective well-being are important because there is evidence that physical health, mental health, substance use, and health care costs may be related to subjective well-being. Fun For Wellness (FFW) is a new online universal intervention designed to promote growth in multiple dimensions of subjective well-being. The purpose of this study was to provide an initial evaluation of the efficacy of FFW to increase subjective well-being in multiple dimensions in a universal sample. The study design was a prospective, double-blind, parallel group randomized controlled trial. Data were collected at baseline and 30 and 60 days-post baseline. A total of 479 adult employees at a major university in the southeast of the USA were enrolled. Recruitment, eligibility verification, and data collection were conducted online. Measures of interpersonal, community, occupational, physical, psychological, economic (i.e., I COPPE), and overall subjective well-being were constructed based on responses to the I COPPE Scale. A two-class linear regression model with complier average causal effect estimation was imposed for each dimension of subjective well-being. Participants who complied with the FFW intervention had significantly higher subjective well-being, as compared to potential compliers in the Usual Care group, in the following dimensions: interpersonal at 60 days, community at 30 and 60 days, psychological at 60 days, and economic at 30 and 60 days. Results from this study provide some initial evidence for both the efficacy of, and possible revisions to, the FFW intervention.

  7. Fun Is More Fun When Others Are Involved.

    Science.gov (United States)

    Reis, Harry T; O'Keefe, Stephanie D; Lane, Richard D

    2017-01-01

    Fun activities are commonly sought and highly desired yet their affective side has received little scrutiny. The present research investigated two features of fun in two daily diary studies and one laboratory experiment. First, we examined the affective state associated with fun experiences. Second, we investigated the social context of fun, considering whether shared fun is more enjoyable than solitary fun. Findings from these studies indicated that fun is associated with both high-activation and low-activation positive affects, and that it is enhanced when experienced with others (especially friends). However, social fun was associated with increases in high-activation but not low-activation positive affect, suggesting that social interaction emphasizes energizing affective experiences. We also found that loneliness moderated the latter effects, such that lonely individuals received a weaker boost from shared compared to solitary fun. These results add to what is known about the impact of social contexts on affective experience.

  8. The fun integration theory: toward sustaining children and adolescents sport participation.

    Science.gov (United States)

    Visek, Amanda J; Achrati, Sara M; Mannix, Heather; McDonnell, Karen; Harris, Brandonn S; DiPietro, Loretta

    2015-03-01

    Children cite "fun" as the primary reason for participation in organized sport and its absence as the number-one reason for youth sport attrition. Therefore, the purpose of this study was to develop a theoretical framework of fun using a novel mixed-method assessment of participants in sport (FUN MAPS) via concept mapping. Youth soccer players (n = 142), coaches (n = 37), and parents (n = 57) were stratified by age, sex, and competition level and contributed their ideas through (a) qualitative brainstorming, identifying all of the things that make playing sports fun for players; (b) sorting of ideas; and (c) rating each idea on its importance, frequency, and feasibility. The FUN MAPS identify the 4 fundamental tenets of fun in youth sport within 11 fun-dimensions composed of 81 specific fun-determinants, while also establishing the youth sport ethos. The FUN MAPS provide pictorial evidence-based blueprints for the fun integration theory (FIT), which is a multitheoretical, multidimensional, and stakeholder derived framework that can be used to maximize fun for children and adolescents to promote and sustain an active and healthy lifestyle through sport.

  9. Teaching for the Fun of It

    Science.gov (United States)

    Mitcham, Karen

    2009-01-01

    The purpose of having fun in the English language arts (ELA) classroom is twofold: (1) build community; and (2) alleviate the monotony, drudgery, and anxiety that reading, speaking, and writing often produce, especially in struggling students and any and all who are future members of Garrison Keillor's Lake Woebegone Professional Organization of…

  10. The Fun Integration Theory: Towards Sustaining Children and Adolescents Sport Participation

    Science.gov (United States)

    Visek, Amanda J.; Achrati, Sara M.; Manning, Heather; McDonnell, Karen; Harris, Brandonn S.; DiPietro, Loretta

    2014-01-01

    BACKGROUND Children cite ‘fun’ as the primary reason for participation in organized sport and its absence as the number one reason for youth sport attrition. Therefore, the purpose of this study was to develop a theoretical framework of fun using a novel mixed-method assessment of participants in sport (FUN MAPS) via concept mapping. METHODS Youth soccer players (n = 142), coaches (n = 37), and parents (n = 57) were stratified by age, sex, and competition level and contributed their “fun” ideas through: (a) qualitative brainstorming, identifying all of the things that make playing sports fun for players; (b) sorting of ideas; and (c) rating each idea on its importance, frequency, and feasibility. RESULTS The FUN MAPS identify the four fundamental tenets of fun in youth sport within 11 fun-dimensions composed of 81 specific fun-determinants, while also establishing the youth sport ethos. CONCLUSION The FUN MAPS provide pictorial evidence-based blueprints for the fun integration theory (FIT), which is a multi-theoretical, multidimensional, and stakeholder derived framework that can be used to maximize fun for children and adolescents in order to promote and sustain an active and healthy lifestyle through sport. PMID:24770788

  11. Choose Health: Food, Fun, and Fitness Youth Curriculum Promotes Positive Behaviors.

    Science.gov (United States)

    Wolfe, Wendy S; Scott-Pierce, Michelle; Dollahite, Jamie

    2017-11-20

    Evaluate whether participation in Choose Health: Food, Fun, and Fitness (CHFFF), a hands-on, experiential curriculum aimed at third- to sixth-graders, resulted in improvements in the targeted obesity and chronic disease prevention behaviors. The researchers evaluated CHFFF in low-income youth participating in 2 federal programs in New York State during 2013-2015. Food and activity behaviors were assessed using the Expanded Food and Nutrition Education Program third- through fifth- and sixth- through eighth-grade pre-post surveys, along with 2 sets of added CHFFF-specific items completed by subsamples. Educators trained in CHFFF had youth complete the surveys as they delivered the curriculum, primarily in schools and after-school programs. Paired t tests showed significant (P < .01) positive changes before to after CHFFF education for consumption of vegetables, fruits, sweetened drinks, nutrition label reading, and other food and activity behaviors. Results provide practice-based evidence that CHFFF promotes positive behavior change in participating youth. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  12. [Wellbeing, team spirit and a fun run for women].

    Science.gov (United States)

    Gougeon, Brigitte

    2017-12-01

    The fun run La Parisienne, has been bringing together in Paris every September for the last 21 years, thousands of women running alongside each other to say no to breast cancer. Many caregivers also take part, in teams or with friends, like at the Odysséa fun run in which families can also participate. Charity sports events for the benefit of research which promote femininity, team spirit, sharing and wellbeing. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  13. Oh What FUN We've Had! Reflections on the Past and a Look to the Future.

    Science.gov (United States)

    Dickinson, Shelly D

    2012-01-01

    In 2011 FUN celebrated 20 years of training tomorrow's neuroscientists today. Over the past two decades we've become an international organization of members dedicated to excellence in teaching and research at the undergraduate level. FUN has enacted its mission through our flagship journal JUNE, student travel awards, faculty awards, education workshops, and regional conferences. More recent initiatives include the equipment loan program, department/program consulting service, the honor society Nu Rho Psi, and neuroscience study abroad opportunities. FUN is poised to continue enhancing undergraduate neuroscience education and research over the next 20 years.

  14. 46 CFR 80.30 - Promotional literature or advertising.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Promotional literature or advertising. 80.30 Section 80... SAFETY STANDARDS AND COUNTRY OF REGISTRY § 80.30 Promotional literature or advertising. (a) Except as provided in paragraph (f) of this section, all promotional literature or advertising in or over any medium...

  15. 25 Years of FUN!

    Science.gov (United States)

    Ramirez, Julio J

    2017-01-01

    Dr. Julio J. Ramirez, the founding president of the Faculty for Undergraduate Neuroscience (FUN), shared the comments below on November 13, 2016 at the 25 th Anniversary of FUN's founding, when Drs. Sally Frutiger, Stephen George, Julio Ramirez, and Dennison Smith were recognized with the Founders Award for their efforts in launching FUN in 1991.

  16. Fun and friends : the impact of workplace fun and constituent attachment on turnover in a hospitality context

    OpenAIRE

    Tews, Michael J.; Michel, John W.; Allen, David G.

    2014-01-01

    Extending the growing body of research on fun in the workplace, this article reports on a study examinining the relationship between fun and employee turnover. Specifically, this research focused on the influence of three forms of fun on turnover – fun activities, coworker socializing and manager support for fun. With a sample of 296 servers from 20 units of a national restaurant chain in the US, coworker socializing and manager support for fun were demonstrated to be significantly related to...

  17. 10 CFR 110.30 - Members of the Nuclear Suppliers Group.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Members of the Nuclear Suppliers Group. 110.30 Section 110.30 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND... Italy Japan Latvia Luxembourg Netherlands New Zealand Norway Poland Portugal Republic of Korea Romania...

  18. Improving health-related fitness in children: the fit-4-Fun randomized controlled trial study protocol

    Directory of Open Access Journals (Sweden)

    Eather Narelle

    2011-12-01

    Full Text Available Abstract Background Declining levels of physical fitness in children are linked to an increased risk of developing poor physical and mental health. Physical activity programs for children that involve regular high intensity physical activity, along with muscle and bone strengthening activities, have been identified by the World Health Organisation as a key strategy to reduce the escalating burden of ill health caused by non-communicable diseases. This paper reports the rationale and methods for a school-based intervention designed to improve physical fitness and physical activity levels of Grades 5 and 6 primary school children. Methods/Design Fit-4-Fun is an 8-week multi-component school-based health-related fitness education intervention and will be evaluated using a group randomized controlled trial. Primary schools from the Hunter Region in NSW, Australia, will be invited to participate in the program in 2011 with a target sample size of 128 primary schools children (age 10-13. The Fit-4-Fun program is theoretically grounded and will be implemented applying the Health Promoting Schools framework. Students will participate in weekly curriculum-based health and physical education lessons, daily break-time physical activities during recess and lunch, and will complete an 8-week (3 × per week home activity program with their parents and/or family members. A battery of six health-related fitness assessments, four days of pedometery-assessed physical activity and a questionnaire, will be administered at baseline, immediate post-intervention (2-months and at 6-months (from baseline to determine intervention effects. Details of the methodological aspects of recruitment, inclusion criteria, randomization, intervention program, assessments, process evaluation and statistical analyses are described. Discussion The Fit-4-Fun program is an innovative school-based intervention targeting fitness improvements in primary school children. The program will

  19. Improving health-related fitness in children: the Fit-4-Fun randomized controlled trial study protocol.

    Science.gov (United States)

    Eather, Narelle; Morgan, Philip J; Lubans, David R

    2011-12-05

    Declining levels of physical fitness in children are linked to an increased risk of developing poor physical and mental health. Physical activity programs for children that involve regular high intensity physical activity, along with muscle and bone strengthening activities, have been identified by the World Health Organisation as a key strategy to reduce the escalating burden of ill health caused by non-communicable diseases. This paper reports the rationale and methods for a school-based intervention designed to improve physical fitness and physical activity levels of Grades 5 and 6 primary school children. Fit-4-Fun is an 8-week multi-component school-based health-related fitness education intervention and will be evaluated using a group randomized controlled trial. Primary schools from the Hunter Region in NSW, Australia, will be invited to participate in the program in 2011 with a target sample size of 128 primary schools children (age 10-13). The Fit-4-Fun program is theoretically grounded and will be implemented applying the Health Promoting Schools framework. Students will participate in weekly curriculum-based health and physical education lessons, daily break-time physical activities during recess and lunch, and will complete an 8-week (3 × per week) home activity program with their parents and/or family members. A battery of six health-related fitness assessments, four days of pedometery-assessed physical activity and a questionnaire, will be administered at baseline, immediate post-intervention (2-months) and at 6-months (from baseline) to determine intervention effects. Details of the methodological aspects of recruitment, inclusion criteria, randomization, intervention program, assessments, process evaluation and statistical analyses are described. The Fit-4-Fun program is an innovative school-based intervention targeting fitness improvements in primary school children. The program will involve a range of evidence-based behaviour change strategies to

  20. Marketing Strategies for Recruiting 4-H Members in West Virginia.

    Science.gov (United States)

    Wingenbach, Gary J.; Nestor, Cheryl; Lawrence, Layle D.; Gartin, Stacy A.; Woloshuk, Jean; Mulkeen, Patricia

    2000-01-01

    According to a survey of 174 West Virginia 4-H members aged 13-18, the Internet and word of mouth were most effective in recruiting new members. Active messages stressing camps, fun, and friendship had the most influence on retention. A statewide marketing plan was recommended. (SK)

  1. BUILDING AN EU MEMBER STATE THROUGH DEMOCRACY PROMOTION: THE CASE OF CROATIA'S PUBLIC ADMINISTRATION REFORM

    Directory of Open Access Journals (Sweden)

    Sonja Grimm

    2013-01-01

    Full Text Available This contribution studies the process of building an EU member state through democracy promotion in the case of Croatia with a special focus on two reform initiatives in the field of Public Administration Reform (PAR. Croatia’s experience is representative of intense efforts of the international community to overcome the consequences of violent state dissolution and civil war. The EU in particular has assisted post-conflict democratization with diplomatic initiatives, the provision of aid, and political conditionality. The Croatian political elite showed great willingness to implement democratic reforms, while at the same time remaining critical of what they viewed as ‘too much’ external interference in domestic state affairs. Based on 30 interviews with Croatian officials, Croatian civil society actors, members of the EU delegation and other representatives of the International donor community, we empirically assess progress and setbacks in Croatia’s public administration reform and explain why some reform initiatives have been successfully implemented while others are still pending.

  2. Smiling is fun: a Coping with Stress and Emotion Regulation Program.

    Science.gov (United States)

    Botella, Cristina; Mira, Adriana; Garcia-Palacios, Azucena; Quero, Soledad; Navarro, Ma Vicenta; Riera López Del Amo, Antonio; Molinari, Guadalupe; Castilla, Diana; Moragrega, Inés; Soler, Carla; Alcañiz, Mariano; Baños, Rosa Maria

    2012-01-01

    Emotional disorders (Anxiety disorders and Mood disorders) are one of the most common health problems worldwide, and their economic costs are very high. People suffering from emotional disorders often use maladaptive emotion regulation strategies and have low coping behaviour that contributes to the presence of clinical symptoms. For this reason, it is important to develop strategies to monitor coping and promote emotion regulation in people exposed to high levels of stress. Information and Communication Technologies (ICT) can help us in this task. Recent systematic reviews of literature on evidence-based CBT treatments delivered via the Internet show that these approaches are effective. We have developed an intervention program ICT based: Coping with Stress and Emotion Regulation Program (Smiling is Fun), a self-applied program via the Internet. Smiling is Fun follows a transdiagnostic perspective, and it is based on CBT techniques. However, it also includes other psychological strategies to improve positive mood. The aim of the present work is to describe Smiling is Fun and the study designed to test its efficacy.

  3. Decomposing the promotional revenue bump for loyalty program members versus nonmembers

    NARCIS (Netherlands)

    van Heerde, H.J.; Bijmolt, T.H.A.

    Loyalty programs lead to a natural split of a firm's customer base into members and nonmembers. To manage both groups effectively, it is essential to know how marketing activities, such as promotions, affect both groups' contributions to revenues. The authors model each group's contribution as the

  4. Enjoyable learning: the role of humour, games, and fun activities in nursing and midwifery education.

    Science.gov (United States)

    Baid, Heather; Lambert, Nicky

    2010-08-01

    Education that captures the attention of students is an essential aspect of promoting meaningful, active learning. Rather than standing at the front of a group of learners simply speaking about a topic, teachers have the opportunity of livening up their teaching with humour, games, and other fun activities. This article critically evaluates the benefits and limitations of humour within nursing education as well as the use of games and fun activities as teaching strategies. Examples of various games and interactive activities are also provided. Copyright 2009 Elsevier Ltd. All rights reserved.

  5. Predictive power of task orientation, general self-efficacy and self-determined motivation on fun and boredom

    Directory of Open Access Journals (Sweden)

    Lorena Ruiz-González

    2015-12-01

    Full Text Available Abstract The aim of this study was to test the predictive power of dispositional orientations, general self-efficacy and self-determined motivation on fun and boredom in physical education classes, with a sample of 459 adolescents between 13 and 18 with a mean age of 15 years (SD = 0.88. The adolescents responded to four Likert scales: Perceptions of Success Questionnaire, General Self-Efficacy Scale, Sport Motivation Scale and Intrinsic Satisfaction Questionnaire in Sport. The results showed the structural regression model showed that task orientation and general self-efficacy positively predicted self-determined motivation and this in turn positively predicted more fun and less boredom in physical education classes. Consequently, the promotion of an educational task-oriented environment where learners perceive their progress and make them feel more competent, will allow them to overcome the intrinsically motivated tasks, and therefore they will have more fun. Pedagogical implications for less boredom and more fun in physical education classes are discussed.

  6. Defining Fun and Seeking Flow in English Language Arts

    Science.gov (United States)

    Romano, Tom

    2009-01-01

    Students have fun with Facebook, MySpace, YouTube, and video games. They have fun text messaging, talking on cell phones, listening to iPods. They have fun at theme parks and hanging out with friends. As their teacher the author wants to introduce students to another kind of fun. This fun can be time consuming, rigorous, and fulfilling. It's the…

  7. Interfaces entre funções executivas, linguagem e intencionalidade

    OpenAIRE

    Tonietto,Lauren; Wagner,Gabriela Peretti; Trentini,Clarissa Marceli; Sperb,Tania Mara; Parente,Maria Alice de Mattos Pimenta

    2011-01-01

    A relação entre linguagem e funções executivas, também conhecidas como funções cognitivas complexas, já foi estabelecida no passado por Luria e Vygotsky. Este artigo tem por objetivo revisar o conceito de funções executivas sob as perspectivas neuropsicológica e cognitiva. Alguns dos reconhecidos modelos sobre processamento das funções executivas são apresentados, assim como estudos recentes sobre funções executivas em crianças. O desenvolvimento das funções executivas é discutido sob o ponto...

  8. The Value of Fun in Physical Activity

    Science.gov (United States)

    El-Sherif, Jennifer L.

    2016-01-01

    According to students, fun, good grades and time with friends are the three key outcomes of physical education. A further review of fun in physical education, from the perspective of students, is included in this article. Selected responses from interviews with high school students reference fun as an important part of their experience in physical…

  9. An overview of the EU Member States support schemes for the promotion of renewable energy sources

    Energy Technology Data Exchange (ETDEWEB)

    Poullikkas, Andreas; Kourtis, George; Hadjipaschalis, Ioannis [Electricity Authority of Cyprus, P.O. Box 24506, 1399 Nicosia (Cyprus)

    2012-07-01

    In this work, an overview of the European Union (EU) Member States support schemes for the promotion of renewable energy sources (RES) is provided. In particular, the status of the electricity generation capacity as well as the RES mixture in the Member States is described. Moreover, the different support schemes such as, investment support, feed-in tariffs (FiTs), tradable green certificates, and fiscal and financial measures which the Member States have adopted for the promotion of RES technologies are discussed in detail. Some Member States are implementing a single support scheme for the promotion of RES for power generation (RES-E), e.g., seven Member States use FiTs, or implement a hybrid support scheme by combining all or some of the four categories of the RES-E supporting schemes. Although, these support schemes have increased the penetration of the RES-E technologies in the Member States, still there is a long way in order to achieve the 2020 target. The reason for this may be that the way these schemes have been used so far, i.e., either as single support schemes or in combination of FiTs or tradable green certificates with investment support and fiscal and financial measures, has been ineffective. A more effective combination could be a hybrid scheme consisting of FiTs with tradable green certificates measures, as in the case of Italy and United Kingdom, that will increase the RES-E penetration and eliminate the possible technical problems which will arise from this increased penetration and have an effect in the stability of the power system.

  10. Putting Fun Back into Learning.

    Science.gov (United States)

    Rao, Srikumar S.

    1995-01-01

    People will learn better if they like what they are learning. Computers offer an extensive library of cases, examples, and stories that are easy to access, fun to work through, and tell students what they want to know. One example is the ASK system, a 15-module, self-study, multimedia program that is fun for trainees to use, which should enhance…

  11. Impact evaluation of "Have Fun - Be Healthy" program: A community based health promotion intervention to prevent childhood obesity.

    Science.gov (United States)

    Pathirana, Thanya; Stoneman, Rebecca; Lamont, Amanda; Harris, Neil; Lee, Patricia

    2018-04-01

    Childhood obesity is rising in prevalence in Australia. This study aimed to evaluate the impact of the "Have Fun-Be Healthy" (HFBH) intervention, delivered in the Playgroup setting, to generate short term changes in dietary, physical activity and sedentary behaviours of children under 5 years and self-efficacy of parents and primary carers. This intervention consisted of eight structured cooking and physical play sessions delivered over a period of 8 weeks by trained facilitators. Pre- and post-intervention data collection was performed using survey questionnaires administered to parents and carers of children under 5 years from low socioeconomic backgrounds recruited through convenience sampling. A total of 640 pre-intervention surveys and 312 post-intervention surveys were returned. The matched response rate was 45.5%. There was an improvement in mean intake of healthy foods and mean physical activity with a decrease in mean intake of unhealthy food and mean screen time in children (P > .05). Following the intervention, parental/carer self-efficacy in promoting healthy eating and limiting screen time of children improved significantly (P < .05). Children's physical activity levels and consumption of healthy foods were positively correlated with parental/carer self-efficacy (P < .01) while screen time and consumption of unhealthy foods were negatively correlated (P < .01). HFBH intervention was successful in improving the dietary, physical activity and screen time in children and parental self-efficacy. SO WHAT?: Being amongst the first of its' kind in Australia, the findings of this study can have implications for developing and implementing similar future health promotion interventions in comparable settings. © 2017 Australian Health Promotion Association.

  12. FUN3D Manual: 13.3

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bil; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2018-01-01

    This manual describes the installation and execution of FUN3D version 13.3, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  13. FUN3D Manual: 12.8

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bil; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2015-01-01

    This manual describes the installation and execution of FUN3D version 12.8, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  14. FUN3D Manual: 13.1

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bil; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2017-01-01

    This manual describes the installation and execution of FUN3D version 13.1, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  15. FUN3D Manual: 13.2

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, William L.; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2017-01-01

    This manual describes the installation and execution of FUN3D version 13.2, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  16. FUN3D Manual: 12.9

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bil; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2016-01-01

    This manual describes the installation and execution of FUN3D version 12.9, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  17. FUN3D Manual: 13.0

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bill; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2016-01-01

    This manual describes the installation and execution of FUN3D version 13.0, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  18. FUN3D Manual: 12.7

    Science.gov (United States)

    Biedron, Robert T.; Carlson, Jan-Renee; Derlaga, Joseph M.; Gnoffo, Peter A.; Hammond, Dana P.; Jones, William T.; Kleb, Bil; Lee-Rausch, Elizabeth M.; Nielsen, Eric J.; Park, Michael A.; hide

    2015-01-01

    This manual describes the installation and execution of FUN3D version 12.7, including optional dependent packages. FUN3D is a suite of computational fluid dynamics simulation and design tools that uses mixed-element unstructured grids in a large number of formats, including structured multiblock and overset grid systems. A discretely-exact adjoint solver enables efficient gradient-based design and grid adaptation to reduce estimated discretization error. FUN3D is available with and without a reacting, real-gas capability. This generic gas option is available only for those persons that qualify for its beta release status.

  19. This is Not a Game - Social Virtual Worlds, Fun, and Learning

    Science.gov (United States)

    Bell, Mark W.; Smith-Robbins, Sarah; Withnail, Greg

    This chapter asks a simple question: what is required to make learning fun in social virtual worlds? Several scholars have connected fun with learning but most of these have centered on the function of games in learning. Studies of learning in massive multiplayer online role playing games connect the game mechanics to how learning occurs. However, few have asked whether learning in a virtual world can be fun if there is no game. In a social virtual world, like Second Life (SL) there are no game mechanics (unlike game worlds like World of Warcraft [WoW]). There are no quests, challenges, rewards or other game elements in SL. So can a virtual world that has no game-content provided be a place where fun learning can take place? We define fun and explore how fun has been related to learning. We explore theories of fun from Koster, Crawford, Csíkszentmihályi and others as well as views of the ways fun is explored as related to the learning experience. With these models in mind, we explore how fun is different in a social virtual world. Drawing on definitions of fun from Castronova and others, we see game structures in virtual worlds may not be needed to have fun. These fun activities include game creation, business interactions, and most importantly, identity play and socialization in a social virtual world. Finally, we propose that if learning is to be successful and fun in a social virtual world it should pay close attention to these two activities.

  20. FUN-L: gene prioritization for RNAi screens.

    Science.gov (United States)

    Lees, Jonathan G; Hériché, Jean-Karim; Morilla, Ian; Fernández, José M; Adler, Priit; Krallinger, Martin; Vilo, Jaak; Valencia, Alfonso; Ellenberg, Jan; Ranea, Juan A; Orengo, Christine

    2015-06-15

    Most biological processes remain only partially characterized with many components still to be identified. Given that a whole genome can usually not be tested in a functional assay, identifying the genes most likely to be of interest is of critical importance to avoid wasting resources. Given a set of known functionally related genes and using a state-of-the-art approach to data integration and mining, our Functional Lists (FUN-L) method provides a ranked list of candidate genes for testing. Validation of predictions from FUN-L with independent RNAi screens confirms that FUN-L-produced lists are enriched in genes with the expected phenotypes. In this article, we describe a website front end to FUN-L. The website is freely available to use at http://funl.org © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  1. Cluster randomised trial of a school-community child health promotion and obesity prevention intervention: findings from the evaluation of fun 'n healthy in Moreland!

    Science.gov (United States)

    Waters, Elizabeth; Gibbs, Lisa; Tadic, Maryanne; Ukoumunne, Obioha C; Magarey, Anthea; Okely, Anthony D; de Silva, Andrea; Armit, Christine; Green, Julie; O'Connor, Thea; Johnson, Britt; Swinburn, Boyd; Carpenter, Lauren; Moore, Graham; Littlecott, Hannah; Gold, Lisa

    2017-08-03

    Multi-level, longer-term obesity prevention interventions that focus on inequalities are scarce. Fun 'n healthy in Moreland! aimed to improve child adiposity, school policies and environments, parent engagement, health behaviours and child wellbeing. All children from primary schools in an inner urban, culturally diverse and economically disadvantaged area in Victoria, Australia were eligible for participation. The intervention, fun 'n healthy in Moreland!, used a Health Promoting Schools Framework and provided schools with evidence, school research data and part time support from a Community Development Worker to develop health promoting strategies. Comparison schools continued as normal. Participants were not blinded to intervention status. The primary outcome was change in adiposity. Repeated cross-sectional design with nested longitudinal subsample. Students from twenty-four primary schools (clusters) were randomised (aged 5-12 years at baseline). 1426 students from 12 intervention schools and 1539 students from 10 comparison schools consented to follow up measurements. Despite increased prevalence of healthy weight across all schools, after 3.5 years of intervention there was no statistically significant difference between trial arms in BMI z score post-intervention (Mean (sd): Intervention 0.68(1.16); Comparison: 0.72(1.12); Adjusted mean difference (AMD): -0.05, CI: -0.19 to 0.08, p = 0.44). Children from intervention schools consumed more daily fruit serves (AMD: 0.19, CI:0.00 to 0.37, p = 0.10), were more likely to have water (AOR: 1.71, CI:1.05 to 2.78, p = 0.03) and vegetables (AOR: 1.23, CI: 0.99 to 1.55, p = 0.07), and less likely to have fruit juice/cordial (AOR: 0.58, CI:0.36 to 0.93, p = 0.02) in school lunch compared to children in comparison schools. More intervention schools (8/11) had healthy eating and physical activity policies compared with comparison schools (2/9). Principals and schools highly valued the approach as a catalyst

  2. Fun and Games and Boredom.

    Science.gov (United States)

    Buday, Richard; Baranowski, Tom; Thompson, Debbe

    2012-08-01

    Serious videogames use entertainment to teach, train, or change behavior. What began in the 1970s as tentative attempts to create learning software is now a recognized videogame genre and an emerging health science. Although more research is needed, a growing body of literature suggests serious videogames can be effective. Support for serious videogames, however, is not universal. An informal Web search reveals numerous skeptics. Critics question serious videogames' entertainment value and, thus, their viability. "How can serious videogames attract and maintain players," the argument goes, "if they aren't as much fun as commercial titles, or even any fun at all?" This article examines the argument that, to be effective, serious videogames should be overtly fun and comparable to commercial off-the-shelf videogames. It explores differences between game developer- and researcher-led projects and discusses ways serious videogames can avoid boring and alienating players. It concludes that direct comparisons between serious and commercial game entertainment values may be misdirected.

  3. Family Fitness Fun

    Science.gov (United States)

    Being active with your family can be a fun way to get everybody moving. All of you will get the health benefits that come from being active. Plus, you’ll be a positive role model, helping your children develop good habits for an active lifetime.

  4. Economics made fun, and made fun of: How ‘Fun’ redefines the Domain and Identity of the Economics Profession

    NARCIS (Netherlands)

    Dekker, E.; Teule, P.

    2012-01-01

    This paper compares two aspects of the use of ‘fun’ within the economics profession. It analyzes the way in which a recently emerged genre of economics-made-fun uses fun and surprising insights to reach new audiences. And it also analyzes the way in which humor is used within and from outside the

  5. Fun & Fit, Phase I: A Program for Overweight African American and Hispanic American Children from Low-Income Families

    Science.gov (United States)

    Meaney, Karen S.; Hart, Melanie A.; Griffin, L. Kent

    2009-01-01

    Fun & Fit is a program designed to create positive physical activity experiences and to promote healthy lifestyle choices among overweight children from low-income African American and Hispanic American families. The program is a collaborative project between Texas Tech University and the Lubbock Independent School District funded through a…

  6. Fun and software exploring pleasure, paradox and pain in computing

    CERN Document Server

    Goriunova, Olga

    2014-01-01

    Fun and Software offers the untold story of fun as constitutive of the culture and aesthetics of computing. Fun in computing is a mode of thinking, making and experiencing. It invokes and convolutes the question of rationalism and logical reason, addresses the sensibilities and experience of computation and attests to its creative drives. By exploring topics as diverse as the pleasure and pain of the programmer, geek wit, affects of play and coding as a bodily pursuit of the unique in recursive structures, Fun and Software helps construct a different point of entry to the understanding of soft

  7. Having Fun and Accepting Challenges Are Natural Instincts: Jigsaw Puzzles to Challenge Students and Test Their Abilities While Having Fun!

    Science.gov (United States)

    Rodenbaugh, Hanna R.; Lujan, Heidi L.; Rodenbaugh, David W.; DiCarlo, Stephen E.

    2014-01-01

    Because jigsaw puzzles are fun, and challenging, students will endure and discover that persistence and grit are rewarded. Importantly, play and fun have a biological place just like sleep and dreams. Students also feel a sense of accomplishment when they have completed a puzzle. Importantly, the reward of mastering a challenge builds confidence…

  8. Cluster randomised trial of a school-community child health promotion and obesity prevention intervention: findings from the evaluation of fun ‘n healthy in Moreland!

    Directory of Open Access Journals (Sweden)

    Elizabeth Waters

    2017-08-01

    Full Text Available Abstract Background Multi-level, longer-term obesity prevention interventions that focus on inequalities are scarce. Fun ‘n healthy in Moreland! aimed to improve child adiposity, school policies and environments, parent engagement, health behaviours and child wellbeing. Methods All children from primary schools in an inner urban, culturally diverse and economically disadvantaged area in Victoria, Australia were eligible for participation. The intervention, fun ‘n healthy in Moreland!, used a Health Promoting Schools Framework and provided schools with evidence, school research data and part time support from a Community Development Worker to develop health promoting strategies. Comparison schools continued as normal. Participants were not blinded to intervention status. The primary outcome was change in adiposity. Repeated cross-sectional design with nested longitudinal subsample. Results Students from twenty-four primary schools (clusters were randomised (aged 5–12 years at baseline. 1426 students from 12 intervention schools and 1539 students from 10 comparison schools consented to follow up measurements. Despite increased prevalence of healthy weight across all schools, after 3.5 years of intervention there was no statistically significant difference between trial arms in BMI z score post-intervention (Mean (sd: Intervention 0.68(1.16; Comparison: 0.72(1.12; Adjusted mean difference (AMD: -0.05, CI: -0.19 to 0.08, p = 0.44. Children from intervention schools consumed more daily fruit serves (AMD: 0.19, CI:0.00 to 0.37, p = 0.10, were more likely to have water (AOR: 1.71, CI:1.05 to 2.78, p = 0.03 and vegetables (AOR: 1.23, CI: 0.99 to 1.55, p = 0.07, and less likely to have fruit juice/cordial (AOR: 0.58, CI:0.36 to 0.93, p = 0.02 in school lunch compared to children in comparison schools. More intervention schools (8/11 had healthy eating and physical activity policies compared with comparison schools (2/9. Principals and

  9. PENGEMBANGAN MODEL PEMBELAJARAN SENAM HEALTY FUN UNTUK ANAK SLB DI KOTA MAGELANG

    Directory of Open Access Journals (Sweden)

    Bernadeta Yovina Anggitasari

    2017-02-01

    Full Text Available The purpose of research is to produce healty Gymnastics Instructional Model Development Fun, Grade V and VI in SLB-C Magelang City. This research is the development of the procedures of product development; (1 analysis, (2 develop initial product form, (3 expert validation test, (4 the first product revision, the revision of the product based on the evaluation of experts and trial I (20 students. Revised used for improvements to the initial product, (5 the trial II (30 students, (6 the revision of the final product is done based on the results of the field trials, (7 the results of a late model gymnastics healty fun for students of classes V and VI which is generated through the revision II trial. Based on the results of research trials I obtained a percentage of 87% (good, the expert evaluation is obtained percentage of 89% (good. II trial research results obtained by the percentage of 96% (excellent. From the trial I and II, there was an increase by a margin of 7%. It can be concluded that the development of gymnastics healty fun learning model can be used as an alternative to teachers provide learning materials rhythmic gymnastics penjasorkes particularly good for classes V and VI SLB-C in Magelang and gymnastic activities that teachers do on a regular basis

  10. Halloween: Have Fun and Stay Safe and Healthy!

    Centers for Disease Control (CDC) Podcasts

    2010-10-25

    Halloween is a fun time for kids, but it's no fun if you get sick or hurt. In this podcast for kids, the Kidtastics offer some simple ways to stay safe and healthy on Halloween.  Created: 10/25/2010 by CDC Office of Women’s Health.   Date Released: 10/25/2010.

  11. Risky Drinking Can Put a Chill on Your Summer Fun

    Science.gov (United States)

    ... on Your Summer Fun Print version Risky Drinking Can Put a Chill on Your Summer Fun Summer ... adults involve the use of alcohol. 1 Swimmers can get in over their heads. Alcohol impairs judgment ...

  12. Fun and Enjoyment in Physical Education: Young People's Attitudes

    Science.gov (United States)

    Dismore, Harriet; Bailey, Richard

    2011-01-01

    Fun and enjoyment are recurring themes in physical education literature, although there has been some debate concerning the distinction between the two concepts. Whereas enjoyment is generally regarded as helpful in fostering positive attitudes towards physical education, fun has not always been considered an appropriate outcome of physical…

  13. KELT-FUN and the discovery of KELT-18b

    Science.gov (United States)

    McLeod, Kim K.; Melton, Casey; Stassun, Keivan G.; KELT Collaboration

    2017-01-01

    The Kilodegree Extremely Little Telescope (KELT) project is a ground-based, wide-field, synoptic sky survey whose primary goal is to discover exoplanets around bright (8 FUN) of observatories to vet and characterize the systems by obtaining more precise light curves and radial-velocities. KELT-FUN now includes nearly 50 telescopes around the world and the photometric follow-up is carried out by a diverse set of partners at universities, small colleges, high schools, and private amateur facilities, often with the help of students. We describe KELT-FUN operations and announce the discovery of KELT-18b, a strongly-irradiated hot Jupiter orbiting a mid-F star.

  14. Fun with Optical Fibres

    Science.gov (United States)

    Alti, Kamlesh

    2017-01-01

    Optical fibres play a very crucial role in today's technologies. Academic courses in optical fibres start at the undergraduate level. Nevertheless, student's curiosity towards optical fibres starts from the school level. In this paper, some fun experiments have been designed for both school and college students, which have some concrete…

  15. Kick, Glide, Pole! Cross-Country Skiing Fun (Part II)

    Science.gov (United States)

    Duoos, Bridget A.

    2012-01-01

    Part I of Kick, Glide, Pole! Cross-Country Skiing Fun, which was published in last issue, discussed how to select cross-country ski equipment, dress for the activity and the biomechanics of the diagonal stride. Part II focuses on teaching the diagonal stride technique and begins with a progression of indoor activities. Incorporating this fun,…

  16. A função exponencial.

    OpenAIRE

    Emerson de Oliveira Dantas

    2014-01-01

    Este trabalho tem por motivação a Equação Funcional de Cauchy f(x + y) = f(x).f(y), característica da Função Exponencial. Para chegarmos a essa equação iniciaremos o nosso estudo pelas definições e demonstrações das Propriedades da Potência de Expoente Real, destacando o caso em que a Potência tem Expoente Irracional, além de fazermos uma proposta pedagógica sobre o ensino de Potenciação, Caracterização da Função Exponencial e Equação Funcional Linear de Cauchy. This work is motivated by t...

  17. How "fun/importance" fit affects performance: relating implicit theories to instructions.

    Science.gov (United States)

    Bianco, Amy T; Higgins, E Tory; Klem, Adena

    2003-09-01

    People experience a regulatory fit when they employ means of goal pursuit that fit their regulatory orientation, and this fit increases motivation that can enhance performance. The present studies extend previous research on regulatory fit to the classic motivational variables of fun and importance. They also examine for the first time the effect on performance of the fit between individuals' implicit theories about a task's fun or importance and their strategic engagement of the task as fun or important as induced by task instructions. In all three studies, task performance was better when the external task instructions "fit" rather than did not fit participants' implicit theory for the task. The implications of these findings for understanding the motivational effects of fun and importance are discussed.

  18. Fun in the Kitchen

    CERN Multimedia

    2004-01-01

    You may be familiar with Microcosm's "Fun with Physics" hands-on activities programme, which is the delight of young and old alike. In order to demonstrate the different states of matter, the "Fun with Physics"1 guides use liquid nitrogen to freeze various substances. Yoghurts, for example, are instantaneously turned into mouth-watering ice-creams! But, did you know that a distinguished chef also uses this technique? Ettore Bocchia, chef at the Grand Hotel Villa Serbelloni in Italy, uses liquid nitrogen at -196°C to freeze the dishes he prepares. Mix some yoghurts, add a soupçon of balsamic vinegar, pour in some liquid nitrogen at -196°C and the result is some delicious ice-cream. This was the recipe that Ettore Bocchia (in the centre of the picture on the left), the distinguished Italian chef, presented at the Gourmet Festival. He gave a demonstration of his skills at the St. Moritz Gourmet Festival, during the week beginning 2 February, in which the best chefs from around the world took part. CERN, whic...

  19. Co-operation Agreement for the Promotion of Nuclear Science and Technology in Latin America and the Caribbean (ARCAL). Status list as of 30 September 2002. Signature and ratification. Declarations/reservations made upon signature

    International Nuclear Information System (INIS)

    2002-01-01

    The document reproduces the text of the Co-operation Agreement for the Promotion of Nuclear Science and Technology in Latin America and the Caribbean (ARCAL) which was opened for signature on 25 September 1998 and shall come into force after deposit of the instrument of ratification by ten Member States. It shall remain in force for ten years, and may be extended by periods of five years if the Member States so agree. By 30 September 2002, there were 18 Signatories to the above Agreement

  20. Powernext 2002: 32 members 30% monthly growth a positive result

    International Nuclear Information System (INIS)

    2002-01-01

    The 1996 European Directive on electricity deregulation was transposed into French law by the Act of February 10, 2000 (Modernization and Development of the Public Electricity Service). On April 12, 2000, a steering committee headed by Euronext Paris launched a feasibility study into the creation of an organised electricity market in France. The other members of the committee were BNP-Paribas, Electrabel, Societe Generale, TotalFinaElf and the French and Belgian transmission system operators, RTE and Elia. The committee's work culminated in the formation on July 30, 2001 of a company - Powernext SA - to run a power exchange, to be called Powernext. Powernext adopted a market model that would ensure liquidity, transparency and orderly trading at all times. The model is based on a close working relationship with the pan-European clearing house Clearnet and RTE. (author)

  1. Fun in the College Classroom: Examining Its Nature and Relationship with Student Engagement

    Science.gov (United States)

    Tews, Michael J.; Jackson, Kathy; Ramsay, Crystal; Michel, John W.

    2015-01-01

    Despite the popular belief that fun has a positive impact in learning contexts, empirical research on fun in the classroom has been limited. To extend research in this area, the goal of this study was to develop and validate a new scale to assess fun in the classroom and examine its relationship with student engagement. The multi-stage scale…

  2. The what as well as the why of animal fun.

    Science.gov (United States)

    Byrne, Richard W

    2015-01-05

    Fun is functional: play is evolution's way of making sure animals acquire and perfect valuable skills in circumstances of relative safety. Yet precisely what animals find fun has seldom been examined for what it can potentially reveal about how they represent and think about the world. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Thermal and chemical evolution in the early solar system as recorded by FUN CAIs: Part I - Petrology, mineral chemistry, and isotopic composition of Allende FUN CAI CMS-1

    Science.gov (United States)

    Williams, C. D.; Ushikubo, T.; Bullock, E. S.; Janney, P. E.; Hines, R. R.; Kita, N. T.; Hervig, R. L.; MacPherson, G. J.; Mendybaev, R. A.; Richter, F. M.; Wadhwa, M.

    2017-03-01

    Detailed petrologic, geochemical and isotopic analyses of a new FUN CAI from the Allende CV3 meteorite (designated CMS-1) indicate that it formed by extensive melting and evaporation of primitive precursor material(s). The precursor material(s) condensed in a 16O-rich region (δ17O and δ18O ∼ -49‰) of the inner solar nebula dominated by gas of solar composition at total pressures of ∼10-3-10-6 bar. Subsequent melting of the precursor material(s) was accompanied by evaporative loss of magnesium, silicon and oxygen resulting in large mass-dependent isotope fractionations in these elements (δ25Mg = 30.71-39.26‰, δ29Si = 14.98-16.65‰, and δ18O = -41.57 to -15.50‰). This evaporative loss resulted in a bulk composition similar to that of compact Type A and Type B CAIs, but very distinct from the composition of the original precursor condensate(s). Kinetic fractionation factors and the measured mass-dependent fractionation of silicon and magnesium in CMS-1 suggest that ∼80% of the silicon and ∼85% of the magnesium were lost from its precursor material(s) through evaporative processes. These results suggest that the precursor material(s) of normal and FUN CAIs condensed in similar environments, but subsequently evolved under vastly different conditions such as total gas pressure. The chemical and isotopic differences between normal and FUN CAIs could be explained by sorting of early solar system materials into distinct physical and chemical regimes, in conjunction with discrete heating events, within the protoplanetary disk.

  4. THE EFFECT OF FUN ATHLETICS EXERCISES ON PSYCHOMOTOR DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Mustafa Güler

    2017-04-01

    Full Text Available The purpose of this research was to investigate the effect of fun athletics exercises on the psychomotor development. The research group consisted of 9 boys and 27 girls with a total of 36 students between 11-14 ages in Kocaeli. In the study, the fun athletics exercises (featured somersault, obstacles to jump, slip under the barrier, slalom, training ladder, double jump, medicine ball handling applied for 90 minutes a day and 3 days a week over 8 weeks. The data was analyzed with Wilcoxon Matched Pairs Test and significance level was determined as α=0.05. According to findings of this study significant differences were found between pre and post tests results. As a result this study showed that fun athletic exercises have a positive effect on 11-14 aged children’s psychomotor development.

  5. Going beyond Fun in STEM

    Science.gov (United States)

    Pittinsky, Todd L.; Diamante, Nicole

    2015-01-01

    The United States education system must improve its ability to produce scientists, engineers, and programmers. Despite numerous national, state, and local efforts to make the study of STEM (science, technology, engineering, and mathematics) subjects more fun in K-12, initial interest in those subjects drops off precipitously in middle and later…

  6. "Ten Things" to Enhance Learning and Fun in the Classroom

    Science.gov (United States)

    Mermelstein, Aaron David

    2016-01-01

    This Teaching Technique introduces a fun, versatile game that gets students thinking, talking, and working together in the English as a second language (ESL) or English as a foreign language (EFL) classroom. It is easy to prepare, and it is a fun and efficient way to enhance learning. The game can be adapted to almost any grade level or ESL/EFL…

  7. Django fun for Girls!

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    Nowadays there is a gender gap in the IT world. Django Girls is a non-profit organization and a community that empowers and helps women to organize free, one-day programming workshops by providing tools, resources and support. Through Django Girls, we want to show our motivation in the IT world, how much fun is to code, and the things they are able to create coding. How is CERN getting involved?

  8. The fun culture in seniors' online communities.

    Science.gov (United States)

    Nimrod, Galit

    2011-04-01

    Previous research found that "fun on line" is the most dominant content in seniors' online communities. The present study aimed to further explore the fun culture in these communities and to discover its unique qualities. The study applied an online ethnography (netnography) approach, utilizing a full year's data from 6 leading seniors' online communities. The final database included about 50,000 posts. The majority of posts were part of online social games, including cognitive, associative, and creative games. The main subjects in all contents were sex, gender differences, aging, grandparenting, politics, faith, and alcohol. Main participatory behaviors were selective timing, using expressive style, and personalization of the online character. Although most participants were "lurkers," the active participants nurtured community norms and relationships, as reflected in the written dialogues. In a reality of limited alternatives for digital games that meet older adults' needs and interests, seniors found an independent system to satisfy their need for play. Seniors' online communities provided a unique form of casual leisure, whose nature varied among different groups of participants. The fun culture seemed to offer participants many desired benefits, including meaningful play, liminality and communitas, opportunity to practice and demonstrate their abilities, and means for coping with aging. Therefore, it may have positive impact on seniors' well-being and successful aging.

  9. FunGeneNet: a web tool to estimate enrichment of functional interactions in experimental gene sets.

    Science.gov (United States)

    Tiys, Evgeny S; Ivanisenko, Timofey V; Demenkov, Pavel S; Ivanisenko, Vladimir A

    2018-02-09

    Estimation of functional connectivity in gene sets derived from genome-wide or other biological experiments is one of the essential tasks of bioinformatics. A promising approach for solving this problem is to compare gene networks built using experimental gene sets with random networks. One of the resources that make such an analysis possible is CrossTalkZ, which uses the FunCoup database. However, existing methods, including CrossTalkZ, do not take into account individual types of interactions, such as protein/protein interactions, expression regulation, transport regulation, catalytic reactions, etc., but rather work with generalized types characterizing the existence of any connection between network members. We developed the online tool FunGeneNet, which utilizes the ANDSystem and STRING to reconstruct gene networks using experimental gene sets and to estimate their difference from random networks. To compare the reconstructed networks with random ones, the node permutation algorithm implemented in CrossTalkZ was taken as a basis. To study the FunGeneNet applicability, the functional connectivity analysis of networks constructed for gene sets involved in the Gene Ontology biological processes was conducted. We showed that the method sensitivity exceeds 0.8 at a specificity of 0.95. We found that the significance level of the difference between gene networks of biological processes and random networks is determined by the type of connections considered between objects. At the same time, the highest reliability is achieved for the generalized form of connections that takes into account all the individual types of connections. By taking examples of the thyroid cancer networks and the apoptosis network, it is demonstrated that key participants in these processes are involved in the interactions of those types by which these networks differ from random ones. FunGeneNet is a web tool aimed at proving the functionality of networks in a wide range of sizes of

  10. Design and Development of RunForFun Mobile Application

    Directory of Open Access Journals (Sweden)

    Anci Anthony

    2018-01-01

    Full Text Available Race run for 5 km or 10 km has been trending recently in many places in Indonesia, especially in Surabaya where there were at least 11 events of race run. The participant's number also increased significantly compared to years before. However, among several race run events, it was seen that some events tended to be replicative and monotone, while among the participants recently were identified the need for increasing the fun factor. RunForFun is a mobile application which designed for participants to reach new experience when participating in a race run event. The mobile application will run on Android OS. The development method of this mobile application would use Reverse Waterfall method. The development of this mobile application uses Ionic Framework which utilizes Cordova as its base to deploy to smartphone devices. Subsequently, RunForRun was tested on 10 participants, and the test shows a significant increase in the fun factor from run race participants.

  11. Fun with Singing Wine Glasses

    Science.gov (United States)

    Boone, Christine; Galloway, Melodie; Ruiz, Michael J.

    2018-01-01

    A fun activity is presented using singing wine glasses for introductory physics students. Students tune a white wine glass and a red wine glass to as many semitones as possible by filling the glasses with the appropriate amounts of water. A smart phone app is used to measure the frequencies of equal-temperament tones. Then plots of frequency…

  12. Kids just wanna have fun: Children's experiences of a weight management programme.

    Science.gov (United States)

    Watson, Libby A; Baker, Martyn C; Chadwick, Paul M

    2016-05-01

    To explore children's accounts of their experiences of the UK's largest childhood obesity programme, MEND (Mind, Exercise, Nutrition...Do it!) (See www.mendprogramme.org). Semi-structured interviews were conducted with children who had completed the MEND obesity programme. Interviews were transcribed verbatim and analysed using Interpretative Phenomenological Analysis (IPA). Fourteen children spanning diverse areas of London comprised this study (eight male, six female), aged between 11 and 14 years and in secondary school. Participants were interviewed a year after completing one of the London-based MEND obesity programmes. This article focuses on the most common and striking theme to emerge from the original dataset (The complete analysis may be found in L. Watson, Unpublished doctoral thesis): Fun. Subthemes were: 'going with the flow'; active participation in activities that led to new experiences ('actually doing it' - seeing the fun side); the importance of others in the experience of fun ('you do games in unity' - 'it's not as fun on your own'). Children have fun when engaged in interactive and varied activities with opportunity for individual feedback and improvement. When designing childhood obesity programmes, conditions that optimise children's experience of fun should be emphasised over didactic and risk-heavy information pertaining to childhood obesity. What is already known on this subject? Continued growth in childhood obesity and its associated health problems, psychological effects, and economic burden make tackling childhood obesity a public health priority. Multicomponent lifestyle interventions to treat childhood obesity within the community have been shown to reduce overweight and obesity from pre- to post-treatment, increase self-esteem, and are found to be acceptable by parents. MEND is the most widely disseminated evidence-based programme of this kind in the United Kingdom. What does this study add? This study is the first qualitative study

  13. Top 10 Reasons Why Children Find Physical Activity to Be Fun

    Science.gov (United States)

    Hopple, Christine J.

    2018-01-01

    "Fun" is considered, from both research and practical knowledge, to be a critical factor in children's decision to participate (or not) in physical activity (PA). Despite its importance, few studies have provided in-depth investigations into what children really mean when they say an activity is fun. The purpose of this article is to…

  14. 76 FR 77175 - New York Fun Factory Fireworks Display, Western Long Island Sound; Mamaroneck, NY

    Science.gov (United States)

    2011-12-12

    ...-AA00 New York Fun Factory Fireworks Display, Western Long Island Sound; Mamaroneck, NY AGENCY: Coast... in support of the New York Fun Factory Fireworks display. This action is necessary to provide for the... the Coast Guard to define regulatory safety zones. On May 10, 2012 New York Fun Factory Events is...

  15. The FUN of identifying gene function in bacterial pathogens; insights from Salmonella functional genomics.

    Science.gov (United States)

    Hammarlöf, Disa L; Canals, Rocío; Hinton, Jay C D

    2013-10-01

    The availability of thousands of genome sequences of bacterial pathogens poses a particular challenge because each genome contains hundreds of genes of unknown function (FUN). How can we easily discover which FUN genes encode important virulence factors? One solution is to combine two different functional genomic approaches. First, transcriptomics identifies bacterial FUN genes that show differential expression during the process of mammalian infection. Second, global mutagenesis identifies individual FUN genes that the pathogen requires to cause disease. The intersection of these datasets can reveal a small set of candidate genes most likely to encode novel virulence attributes. We demonstrate this approach with the Salmonella infection model, and propose that a similar strategy could be used for other bacterial pathogens. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Fun and games in Berkeley: the early years (1956-2013).

    Science.gov (United States)

    Tinoco, Ignacio

    2014-01-01

    Life at Berkeley for the past 57 years involved research on the thermodynamics, kinetics, and spectroscopic properties of RNA to better understand its structures, interactions, and functions. We (myself and all the graduate students and postdocs who shared in the fun) began with dinucleoside phosphates and slowly worked our way up to megadalton-sized RNA molecular motors. We used UV absorption, circular dichroism, circular intensity differential scattering, fluorescence, NMR, and single-molecule methods. We learned a lot and had fun doing it.

  17. The Members of the Agency

    International Nuclear Information System (INIS)

    2006-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.62) is Montenegro which deposited its Instrument of Acceptance of the Statute on 30 October 2006. The Attachment hereto shows the dates on which the present 143 Member States became Members

  18. Work or Fun? How Task Construal and Completion Influence Regulatory Behavior

    OpenAIRE

    Juliano Laran; Chris Janiszewski

    2011-01-01

    Volitional behaviors can be construed as "work" (extrinsically motivated) or as "fun" (intrinsically motivated). When volitional behaviors are construed as an obligation to work, completing the behavior depletes a consumer, and subsequent self-control becomes more difficult. When volitional behaviors are construed as an opportunity to have fun, completing the behavior vitalizes a consumer, and subsequent self-control becomes easier. Six studies show how individual differences and contextual f...

  19. Linearized FUN3D for Rapid Aeroelastic and Aeroservoelastic Design and Analysis, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — In Phase I, a prototypical FUN3D-based ZONA Euler Unsteady Solver (FunZEUS) was developed to generate the Generalized Aerodynamic Forces (GAFs) due to structural...

  20. Waiting as Part of the Fun: Interactive Gaming in Theme Park Queues

    NARCIS (Netherlands)

    Heger, Chris; Offermans, S.A.M.; Frens, J.W.; Wouters, I.H.C.; Kimman, F.P.F.; Tieben, R.; Offermans, S.A.M.; Nagtzaam, H.A.H.

    2009-01-01

    People visiting theme parks intend to have a day of fun. Yet a larger part of the time is spent queuing for rides rather than in the actual rides, which does not contribute to the intended fun experience. Current efforts therefore either make the queue as bearable as possible or try to get rid of it

  1. Height, fun and safety in the design of children's playground equipment.

    Science.gov (United States)

    Wakes, Sarah; Beukes, Amanda

    2012-01-01

    The study reported in this paper adopted a holistic design approach to investigate issues associated with height related playground injuries from a users' perspective. The main objective was to gain an understanding of the relationship between height and fun so as to establish practical guidelines for addressing the causes of height related injuries whilst maintaining the attributes of playground equipment that children find fun and challenging. Results show that, on the one hand, the risk of injury increases when height is coupled with the use of upper body strength and, on the other hand, that coordination is a greater source of fun and challenge than height for children. Accordingly, it is suggested that the level of risk of injury attached to children's playground equipment can be reduced when the use of lower body strength and coordination are combined with lower free fall heights.

  2. Assessment of FUN-1 vital dye staining: Yeast with a block in the vacuolar sorting pathway have impaired ability to form CIVS when stained with FUN-1 fluorescent dye.

    Science.gov (United States)

    Essary, Brandin D; Marshall, Pamela A

    2009-08-01

    FUN-1 [2-chloro-4-(2,3-dihydro-3-methyl-(benzo-1,3-thiazol-2-yl)-methylidene)-1-phenylquinolinium iodide] is a fluorescent dye used in studies of yeast and other fungi to monitor cell viability in the research lab and to assay for active fungal infection in the clinical setting. When the plasma membrane is intact, fungal cells internalize FUN-1 and the dye is seen as diffuse green cytosolic fluorescence. FUN-1 is then transported to the vacuole in metabolically active wild type cells and subsequently is compacted into fluorescent red cylindrical intravacuolar structures (CIVS) by an unknown transport pathway. This dye is used to determine yeast viability, as only live cells form CIVS. However, in live Saccharomyces cerevisiae with impaired protein sorting to the yeast vacuole, we report decreased to no CIVS formation, depending on the cellular location of the block in the sorting pathway. Cells with a block in vesicle-mediated transport from the Golgi to prevacuolar compartment (PVC) or with a block in recycling from the PVC to the Golgi demonstrate a substantial impairment in CIVS formation. Instead, the FUN-1 dye is seen either in small punctate structures under fluorescence or as diffuse red cytosol under white light. Thus, researchers using FUN-1 should be cognizant of the limitations of this procedure in determining cell viability as there are viable yeast mutants with impaired CIVS formation.

  3. Função cócleo-vestibular após hemisferectomias cerebrais: apresentação de dois casos

    Directory of Open Access Journals (Sweden)

    Sérgio Paula Santos

    1957-03-01

    Full Text Available O exame cócleo-vestibular de dois pacientes hemisferectomizados mostrou: hipoacusia bilateral não ultrapassando 30 db, sendo maior no ouvido contralateral; não houve recrutamento de volume; desproporção entre audiometria vocal e tonal; a função vestibular não se mostrou prejudicada pela prova calórica fria.

  4. Linearized FUN3D for Rapid Aeroelastic and Aeroservoelastic Design and Analysis, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall objective of this Phase I project is to develop a hybrid approach in FUN3D, referred herein to as the Linearized FUN3D, for rapid aeroelastic and...

  5. Evaluation of activities promoting fruits and vegetables consumption in 8 countries members of the Global Alliance for Promoting Fruit and Vegetable Consumption “5 a day” – AIAM5

    Directory of Open Access Journals (Sweden)

    Manuel Moñino

    2016-12-01

    Full Text Available Introduction: This article compiles practices promoting fruits and vegetables consumption launched by eight members of AIAM5 - Global Alliance for Promoting Fruits and Vegetables Consumption “5 a day”, with the aim of identifying best practices in the approaching strategies, programs and activities to encourage fruits and vegetables consumption. Material and Methods: A questionnaire designed to categorize and identify strengths, weaknesses, opportunities, cost-effectiveness, feasibility and practices with the greatest potential to adapt to national health promoting policies, was used. Questionnaires from eight countries from AIAM5 were evaluated: Mexico, Chile, Costa Rica, Venezuela, Colombia, Bolivia, Nicaragua and Spain. Results: One of the greatest strengths of the organizations of AIAM5 is the prestige and the professional, technical and academic knowledge that back up their activities. One evident weakness of their strategies is the lack of measuring practices of the impact of the implemented activities, and the evaluation of their cost-effectiveness. It was also observed that some of the entities that carry out the programs “5 a day” are conceived as social enterprises with diverse types of partners and allies. Conclusions: It is recommended that AIAM5 members should make an effort to measure the impact of their activities and interventions by setting quantifiable goals, and using indicators to assess the degree of achievement of the activities carried out. It is also recommended to exploit the niche of opportunities provided by the Corporate Social Responsibility to help them achieve their objectives of promoting fruits and vegetables consumption.

  6. Activating chronic kidney disease patients and family members through the Internet to promote integration of care

    Directory of Open Access Journals (Sweden)

    Michael Trisolini

    2004-10-01

    Full Text Available Purpose: To describe the potential role of the Internet as a vehicle for improving integration of care through activating chronic kidney disease patients and their family members. Also, to describe how that potential is being developed through a website sponsored by the Medicare program in the United States. Background: The Internet is expanding at a rapid rate, and health-related websites are one of its most popular features. Efforts to promote integration of care have focused mainly on providers up to now, and more emphasis is needed on the potential roles of patients. Chronically ill patients have particular needs for improved education about their conditions and enhanced involvement in care planning and treatment decisions. Medicare developed the Dialysis Facility Compare website to serve those goals for people with chronic kidney disease. Methods: We conducted qualitative research with 140 chronic kidney disease patients and family members, and 130 renal care professionals to evaluate and improve the Dialysis Facility Compare website. A series of 19 focus groups, 13 triads (small focus groups, and 56 individual interviews were conducted in four regions of the United States and by telephone. Results: We found that the Dialysis Facility Compare website has the potential to improve integration of care for people with chronic kidney disease in at least three ways. First: by expanding the roles of patients as members of the multi-disciplinary team of caregivers treating their disease. Second: through better integration of the informal care provided in the home and community with the formal care provided by health professionals. Third: by improving coordination of between care provided in the pre-dialysis and dialysis phases of the disease. Discussion: We developed recommendations for revising and enhancing the Dialysis Facility Compare website in a number of ways to better promote patient activation and integration of care. The unique features

  7. Suitability of the Miller Function and Participation Scales (M-FUN) for use with Israeli Children.

    Science.gov (United States)

    Rihtman, Tanya; Parush, Shula

    2014-01-01

    OBJECTIVE. Our aim was to generate a Hebrew translation of the Miller Function and Participation Scales (M-FUN) and assess the validity of U.S. norms for Israeli children. METHOD. All components of the M-FUN were translated, and a pilot study revealed a need for further investigation. The Hebrew M-FUN's fine, gross, and visual-motor (VM) components and M-FUN participation questionnaires were administered to 267 Israeli children (128 boys, 139 girls; mean age = 59.21 mo, standard deviation = 17.84). RESULTS. Significant correlations supported construct validity between age and all motor and participation scores as well as age-group differences. Significant differences between the U.S. and Israeli samples were found only for the VM score. Participation and motor scores were significantly correlated. CONCLUSION. Although VM score results should be interpreted with caution, we provide evidence for use of the fine and gross motor norms and the U.S. criterion-referenced participation scores of the M-FUN with Israeli children. Copyright © 2014 by the American Occupational Therapy Association, Inc.

  8. Cognitive function assessment in idiopathic Parkinson's disease Avaliação da função cognitiva em doença de Parkinson idiopática

    Directory of Open Access Journals (Sweden)

    Mauro R. Piovezan

    2007-12-01

    Full Text Available Idiopathic Parkinson’s disease (PD is characterized by reduced nigrostriatal and cortical dopaminergic influence, with changes in movement and, subsequently, behavioral and cognitive disturbances. We studied cognitive impairment in Parkinson’s disease by assessing a group of 30 idiopathic Parkinson’s disease patients with an average age of 64.23 years (PG group and compared our findings with those for a control group of 30 patients (CG group. All the patients were submitted to the following assessments: motor function, using the UPDRS; staging, using the Hoehn-Yahr scales (PG group only; depression, using the Montgomery-Asberg scale; attention impairment; verbal fluency (FAR and animals; cognitive function, using the Mini Mental State Examination; visuospatial and executive functions; and clock drawing. In addition to altered motor function in PD patients, we found statistically significant differences between PD patients and controls in terms of cognitive function, verbal, executive and visuospatial functions, and attention deficits. Depression was more prevalent in the PG group.A doença de Parkinson idiopática (DP caracteriza-se pela redução da influência dopaminérgica nigroestriatal e cortical, com alterações em movimentos e posteriormente, comportamentais e cognitivas. Estudamos o comprometimento cognitivo de pacientes portadores de DP, avaliando 30 pacientes com doença de Parkinson idiopática (GP com média de idade de 64,23 anos e os comparamos com um grupo controle (GC de 30 pacientes. Todos os pacientes foram submetidos as seguintes avaliações: motora pela escala de UPDRS; estadiamento pela escala de Hoehn-Yahr (somente GP; depressão pela escala de Montgomery-Asberg; comprometimento da atenção; fluência verbal (FAR e animais; função cognitiva pelo Mini Exame do Estado Mental; funções visuoespaciais e executivas e desenho do relógio. Concluímos que na DP os pacientes apresentam além das alterações motoras

  9. CTF: Computer security competitions for learning and fun

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    CTF hacking competitions condense practical security knowledge in short and measurable challenges, in short: education, fun, prizes and fame! This talk is an introduction to these type of competitions from a player perspective over the years.

  10. THE ROLES OF TRANSLATED YOUNG ADULT FICTION IN ACHIEVEMENT OF YOUNG ADULT DEVELOPMENT IN PITIMOSS FUN LIBRARY

    Directory of Open Access Journals (Sweden)

    Fuji Muliasari

    2017-02-01

    recommendation for the members based on their developmental and chronological age. Keywords: collection development, Pitimoss Fun Library, translated young adult fiction, young adult development

  11. Assessing Fun Items' Effectiveness in Increasing Learning of College Introductory Statistics Students: Results of a Randomized Experiment

    Science.gov (United States)

    Lesser, Lawrence M.; Pearl, Dennis K.; Weber, John J., III

    2016-01-01

    There has been a recent emergence of scholarship on the use of fun in the college statistics classroom, with at least 20 modalities identified. While there have been randomized experiments that suggest that fun can enhance student achievement or attitudes in statistics, these studies have generally been limited to one particular fun modality or…

  12. Putting the Fun Back into Fluency Instruction

    Science.gov (United States)

    Cahill, Mary Ann; Gregory, Anne E.

    2011-01-01

    Based on recent research in fluency instruction, the authors present a scenario in which a teacher focuses her fluency instruction on authentic fluency tasks based in performance. Beginning with establishing a student-friendly definition of fluency and culminating with student engagement in fun fluency activities, this article explores the…

  13. Interview with Alison Bechdel about her presentation of Fun Home in Paris and Tours

    Directory of Open Access Journals (Sweden)

    Anne Crémieux

    2007-09-01

    Full Text Available “Self-portrait by Alison Bechdel,” Courtesy of the authorTransat: How has Fun Home’s reception been different in nature from the reactions to Dykes to Watch Out For? Alison Bechdel: Fun Home has had a very different reception than Dykes to Watch Out For. It’s a very different type of book. I don’t want to downplay DTWOF—I’m very proud of the series, and I think it’s been a worthy contribution to queer culture as well as to the comics genre. But Fun Home was a real creative leap for me. Creati...

  14. Observação do desenvolvimento de linguagem e funções auditiva e visual em lactentes Observation of language, visual and hearing function development in infants

    Directory of Open Access Journals (Sweden)

    Maria Cecília Marconi Pinheiro Lima

    2004-02-01

    Full Text Available OBJETIVO: Investigar o desenvolvimento da linguagem e das funções auditiva e visual em lactentes de creche, a partir da avaliação realizada por educadores. MÉTODOS: Foram avaliados 115 lactentes, nos anos de 1998 a 2001, usuários de uma creche da área da saúde de uma universidade do Estado de São Paulo. Foi utilizado o "Protocolo da Observação do Desenvolvimento de Linguagem e das Funções Auditiva e Visual", com 39 provas no total, para a avaliação dos lactentes de 3 até 12 meses de idade. A aplicação desse Protocolo foi feita pelas educadoras da creche, devidamente treinadas. Utilizou-se o teste de Qui-quadrado ou Exato de Fisher. O nível de significância adotado foi de 5%. RESULTADOS: Os lactentes apresentaram um padrão diferente no desenvolvimento da linguagem quanto ao início do balbucio e das primeiras palavras, bem como na função visual, quanto à imitação e uso de jogos gestuais e de seguir ordem com uso de gestos. CONCLUSÕES: O ambiente creche propicia condições para um outro padrão de desenvolvimento de linguagem e das funções auditiva e visual. Ações de prevenção na creche devem integrar as áreas de saúde e educação num objetivo comum.OBJECTIVE: To investigate language, visual and hearing function development among infants in a day-care center based on educators' assessments. METHODS: One hundred and fifteen infants who attended a day-care center at one university of the São Paulo State, Brazil, were assessed during the period between 1998 and 2001. The "Protocol for Observation of Language, Visual and Hearing Function Development," containing a total of 39 standardized tests, was utilized to assess infants from three to twelve months old. The protocol was applied by trained educators, members of the day-care center staff. Statistical analysis was carried out using Chi-square test or Fischer's exact test at p <0.05. RESULTS: Infants showed different language development patterns as for

  15. Função Atrial Esquerda Prejudicada Associada com a Fibrilação Atrial Paroxística na Hipertensão

    Directory of Open Access Journals (Sweden)

    Erhan Tenekecioglu

    2014-04-01

    Full Text Available Fundamento: A hipertensão arterial é o fator de risco mais prevalente e modificável para a fibrilação atrial. A sobrecarga de pressão no átrio esquerdo induz alterações fisiopatológicas que ocasionam alterações na função contrátil e nas propriedades elétricas. Objetivo: Nesse estudo, o objetivo foi avaliar a função do átrio esquerdo em pacientes hipertensos para determinar a associação entre a função atrial esquerda e a fibrilação atrial paroxística (FAP. Método: Foram estudados 57 pacientes hipertensos (idade: 53 ± 4 anos, fração de ejeção do ventrículo esquerdo: 76 ± 6,7%, incluindo 30 pacientes consecutivos com FAP e 30 indivíduos de controle pareados por idade. Os volumes do átrio esquerdo (AE foram medidos através do método biplano de Simpson modificado. Foram determinados três tipos de volume do AE: volume máximo do AE (AEVmax, contração atrial prematura do AE (AEVpreA e volume mínimo do AE (AEVmin. Foram calculadas as funções de esvaziamento do AE. Volume total de esvaziamento do AE = AEVmax - AEVmin e a FEtotal do AE = (AEVmax - AEVmin/AEVmax, volume de esvaziamento passivo do AE = AEVmax-AEVpreA, e a FE do AE = (AEVmax - AEVpreA/AEVmax, o volume de esvaziamento ativo do AE = AEVpreA- AEVmin e a FE ativa do AE = (AEVpreA - AEVmin/AEVpreA. Resultados: O período hipertenso é maior no grupo de hipertensos com FAP. O AEVmax aumentou significativamente no grupo de hipertensos com FAP quando comparado ao grupo de hipertensos sem FAP (p = 0,010. A FEAE diminuiu significativamente no grupo de hipertensos com FAP em comparação com o grupo de hipertensos sem FAP (p = 0,020. A' diminuiu no grupo de hipertensos com FAP quando comparado com hipertensos sem FAP (p = 0,044. Conclusão: O volume aumentado do AE e função de esvaziamento ativa do AE prejudicada foram associados com a FAP em pacientes hipertensos não tratados. Um período hipertenso mais longo está associado com a FAP.

  16. Disentangling Fun and Enjoyment in Exergames Using an Expanded Design, Play, Experience Framework: A Narrative Review.

    Science.gov (United States)

    Mellecker, Robin; Lyons, Elizabeth J; Baranowski, Tom

    2013-06-01

    With exergames (as with physical activity in general), more intense and longer-duration game play should accrue more health benefits. Exergames, however, appear to be played for relatively short durations, often at medium or lower intensities. Ostensibly games are played for fun or enjoyment. Enhancing the fun or enjoyment experienced during exergame play should enhance the intensity and duration of physical activity, and thereby the health benefits. Research, reviewed herein, indicates fun and/or enjoyment in games are inherently laden with psychosocial, physiological, and embodiment substrates. Physical activity may also have separate or closely related psychosocial, physiological, and embodiment enjoyment substrates. Research is needed to integrate these levels of experience and to identify the game mechanics that enhance, and even maximize, the fun or enjoyment experienced in exergames, to thereby increase the health benefit.

  17. Learning can’t be fun, can it

    NARCIS (Netherlands)

    Veugen, J.I.L.; drs Lange, de M.; Siebenhandl, K.; Wagner, M.; Zauchner, S.

    2007-01-01

    Inspired by research by Carrie Heeter et al. and the MIT Games-to-Teach project, we set up a small-scale empirical study on two educational games on Art aimed at primary school children. We found that both boys and girls liked to play these games; that one game scored better on our “fun index” and

  18. The effects of chronic achievement motivation and achievement primes on the activation of achievement and fun goals.

    Science.gov (United States)

    Hart, William; Albarracín, Dolores

    2009-12-01

    This research examined the hypothesis that situational achievement cues can elicit achievement or fun goals depending on chronic differences in achievement motivation. In 4 studies, chronic differences in achievement motivation were measured, and achievement-denoting words were used to influence behavior. The effects of these variables were assessed on self-report inventories, task performance, task resumption following an interruption, and the pursuit of means relevant to achieving or having fun. Findings indicated that achievement priming (vs. control priming) activated a goal to achieve and inhibited a goal to have fun in individuals with chronically high-achievement motivation but activated a goal to have fun and inhibited a goal to achieve in individuals with chronically low-achievement motivation.

  19. Modelos de distribuição de diâmetros utilizando a função log gama

    Directory of Open Access Journals (Sweden)

    Daniel Henrique Breda Binoti

    2013-03-01

    Full Text Available Objetivou-se neste estudo avaliar a eficiência da função log gama para a descrição da estrutura diamétrica de povoamentos equiâneos, bem como propor um modelo de distribuição diamétrica utilizando esta função. A função foi ajustada a dados de parcelas permanentes de inventário, mensuradas em seis idades. A aderência da função aos dados foi comprovada pelo teste Kolmogorov-Smirnov. A análise gráfica de resíduos não apresentou tendenciosidade para os modelos construídos. A função log gama pode ser utilizada para a construção de modelos de distribuição diamétrica de eucalipto.

  20. Plan de empresa baking fun

    OpenAIRE

    Castiblanco Gutiérrez, Daniella María; Blanco Barrios, Andrea

    2016-01-01

    Baking fun es una empresa dedicada a la producción y comercialización de snacks saludables para niños. Sabemos que el momento de la comida no es fácil para los padres, y más aun cuando quieren alimentar con frutas y verduras a los más pequeños. Es por esto que nuestros snacks, a diferencia de los snacks tradicionales buscan combinar lo saludable con lo divertido, para que puedan alimentar balanceadamente a sus hijos mientras ellos se divierten y disfrutan nuestros snacks.

  1. Recent activities for the promotion of gender equality in the societies of physics in Japan

    Science.gov (United States)

    Mori, H.; Sasao, M.; Nemoto, K.; Tamechika, E.; Watanabe, M. O.

    2015-12-01

    Although the percentage of women members increases from 2% to 6% in the last 30 years, the ratio is still low in both the Physical Society of Japan and the Japan Society of Applied Physics. Recent activities for the promotion of gender equality in both societies, the development of the next generation of members, organizing international workshops and domestic symposiums, and so on, are introduced in this paper.

  2. SemFunSim: a new method for measuring disease similarity by integrating semantic and gene functional association.

    Directory of Open Access Journals (Sweden)

    Liang Cheng

    Full Text Available Measuring similarity between diseases plays an important role in disease-related molecular function research. Functional associations between disease-related genes and semantic associations between diseases are often used to identify pairs of similar diseases from different perspectives. Currently, it is still a challenge to exploit both of them to calculate disease similarity. Therefore, a new method (SemFunSim that integrates semantic and functional association is proposed to address the issue.SemFunSim is designed as follows. First of all, FunSim (Functional similarity is proposed to calculate disease similarity using disease-related gene sets in a weighted network of human gene function. Next, SemSim (Semantic Similarity is devised to calculate disease similarity using the relationship between two diseases from Disease Ontology. Finally, FunSim and SemSim are integrated to measure disease similarity.The high average AUC (area under the receiver operating characteristic curve (96.37% shows that SemFunSim achieves a high true positive rate and a low false positive rate. 79 of the top 100 pairs of similar diseases identified by SemFunSim are annotated in the Comparative Toxicogenomics Database (CTD as being targeted by the same therapeutic compounds, while other methods we compared could identify 35 or less such pairs among the top 100. Moreover, when using our method on diseases without annotated compounds in CTD, we could confirm many of our predicted candidate compounds from literature. This indicates that SemFunSim is an effective method for drug repositioning.

  3. Serious Fun: Life-Deep Learning of Koi Hobbyists

    Science.gov (United States)

    Liu, Chi-Chang

    2012-01-01

    Hobby activities can be viewed through the lens of informal, free-choice learning. A wide range of hobbies combine fun and learning-intensive practices, and can contribute to scientific literacy. Hobby learning involves clear goal orientation, persistence and effort, and often results in more richly and strongly connected knowledge; traits highly…

  4. Materials Delivered by Member States

    International Nuclear Information System (INIS)

    1969-01-01

    In this document the Director General is reporting to the Members of the Agency, under Article IX. G of the Statute, the quantities of materials delivered by Members up to 30 June 1969 in compliance with requests the Agency had made under Article IX. D

  5. Learning through a Game - Exploring Fun and Learning in a Project Management Game

    OpenAIRE

    Hansen, Daniel Sollie; Storjord, David

    2016-01-01

    The goal of this thesis is to explore the teaching capabilities of games by motivating players through fun. We do this by first exploring perspectives of fun and learning in games; project management concepts and previous games. From these findings we implement our own game prototype where the player learns project management concepts simultaneously as they learn the game. This prototype is then evaluated through a number of experiments. Finally we discuss the results of the experiments and c...

  6. Materials Delivered by Member States

    International Nuclear Information System (INIS)

    1975-01-01

    In this document the Director General is reporting to the Members of the Agency, under Article IX. G of the Statute, the quantities of materials which Members had delivered up to 30 June 1975, in compliance with requests the Agency had made under Article IX. D

  7. Promoting Health in Early Childhood Environments: A Health-Promotion Approach

    Science.gov (United States)

    Minniss, Fiona Rowe; Wardrope, Cheryl; Johnston, Donni; Kendall, Elizabeth

    2013-01-01

    This paper investigates the mechanisms by which a health-promotion intervention might influence the health-promoting behaviours of staff members working in early childhood centres. The intervention was an ecological health-promotion initiative that was implemented within four early childhood centres in South-East Queensland, Australia. In-depth,…

  8. O sujeito psicótico e a função do delírio

    OpenAIRE

    Briggs, Raquel; Rinaldi, Doris

    2014-01-01

    Este trabalho aborda o conceito de delírio e sua função na estrutura psicótica. A psicanálise considera o delírio, por um lado, fenômeno elementar e, por outro, tentativa de cura, portador de uma verdade. O presente trabalho objetiva abordar a estruturação delirante, assim como a função da mesma para o sujeito paranoico, no sentido de situar a direção de tratamento na clínica da paranoia. A partir de um caso clínico e embasando-se nos conceitos da psicanálise, discute-se a função do mesmo par...

  9. Avaliação da função renal do idoso em duas horas

    OpenAIRE

    Benarab,Maria do Carmo B. Sammartino; Castiglia,Yara Marcondes Machado; Vianna,Pedro Thadeu Galvão; Braz,José Reinaldo Cerqueira

    2005-01-01

    JUSTIFICATIVA E OBJETIVOS: Os idosos têm diminuição progressiva da função renal e os hipertensos, maior risco de lesão renal adicional no intra-operatório. Avalia-se a função renal pela depuração da creatinina, com débito urinário de 24 horas, para diluir o erro de possível volume vesical residual (VVR). O objetivo deste trabalho foi avaliar a função renal pré-operatória de idosos hipertensos e não-hipertensos, com débito urinário de duas horas, utilizando aparelho de ultra-som portátil para ...

  10. Healthy habits are no fun: How Dutch youth negotiate discourses about food, fit, fat, and fun.

    Science.gov (United States)

    van Amsterdam, Noortje; Knoppers, Annelies

    2018-03-01

    In this article, we use the notion of "biopedagogical practices" to explore how Dutch youth respond to health messages that focus on body weight. Previous studies suggest that such health messages encourage body dissatisfaction in youth. Few studies, however, focus on the local/cultural specificity of youth's responses to these biopedagogical practices. In this article, we address questions about the re-interpretation of and resistance to health messages that Dutch youth engage in and how these can be understood in their local context. The data were drawn from two previously conducted studies in which a total of 64 Dutch teenagers (aged 12-18 years) took part. We employed a variety of qualitative data collection methods and a feminist poststructuralist perspective to analyze how Dutch youth negotiate biopedagogical practices about health. The results show that our participants constructed health in terms of appearance and reproduced negative constructions regarding fat embodiment. Yet they also often circumvented "healthy" lifestyle behaviors prescribed by biopedagogies of health. They did so first by avoiding physical activities because they were afraid of displaying fat embodiment in the settings of sport and physical education where surveillance is omnipresent. Second, they disregarded advice about healthy eating by drawing on having fun as an alternative discursive resource. We argue that having fun is both part of youth culture and characteristic of the discourse about sociability ( gezelligheid) that is a central element of Dutch culture.

  11. A Nonlinear Modal Aeroelastic Solver for FUN3D

    Science.gov (United States)

    Goldman, Benjamin D.; Bartels, Robert E.; Biedron, Robert T.; Scott, Robert C.

    2016-01-01

    A nonlinear structural solver has been implemented internally within the NASA FUN3D computational fluid dynamics code, allowing for some new aeroelastic capabilities. Using a modal representation of the structure, a set of differential or differential-algebraic equations are derived for general thin structures with geometric nonlinearities. ODEPACK and LAPACK routines are linked with FUN3D, and the nonlinear equations are solved at each CFD time step. The existing predictor-corrector method is retained, whereby the structural solution is updated after mesh deformation. The nonlinear solver is validated using a test case for a flexible aeroshell at transonic, supersonic, and hypersonic flow conditions. Agreement with linear theory is seen for the static aeroelastic solutions at relatively low dynamic pressures, but structural nonlinearities limit deformation amplitudes at high dynamic pressures. No flutter was found at any of the tested trajectory points, though LCO may be possible in the transonic regime.

  12. The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe

    Directory of Open Access Journals (Sweden)

    Bussotti F

    2012-12-01

    Full Text Available The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe. FunDivEUROPE is a new project aiming at a deeper understanding of the role of forest diversity on ecosystem functions and service provisioning for society. This project combines three scientific platforms: experimental, exploratory and inventory. The exploratory platform is based on the observation of a broad range of properties, traits and ecological processes on a network of ca. 240 natural forest sites representing a gradient of tree species diversity in six focal regions of Europe (Spain, Italy, Germany, Poland, Finland and Romania. The Italian sites are located on the hills of central and Southern Tuscany and represent the category “thermophilous deciduous forest”. Almost one year of fieldwork was needed to select and characterize 36 plots measuring 30 x 30 m. Selection was based on criteria concerning tree mixtures and richness, structural parameters and main environmental variables. The main features of these sites are synthetically presented in this paper together with a short description of the project structure and scope. The aim is also to enhance dissemination of the potential implications for a sustainable forest management in Italy.

  13. Modularization and Validation of FUN3D as a CREATE-AV Helios Near-Body Solver

    Science.gov (United States)

    Jain, Rohit; Biedron, Robert T.; Jones, William T.; Lee-Rausch, Elizabeth M.

    2016-01-01

    Under a recent collaborative effort between the US Army Aeroflightdynamics Directorate (AFDD) and NASA Langley, NASA's general unstructured CFD solver, FUN3D, was modularized as a CREATE-AV Helios near-body unstructured grid solver. The strategies adopted in Helios/FUN3D integration effort are described. A validation study of the new capability is performed for rotorcraft cases spanning hover prediction, airloads prediction, coupling with computational structural dynamics, counter-rotating dual-rotor configurations, and free-flight trim. The integration of FUN3D, along with the previously integrated NASA OVERFLOW solver, lays the ground for future interaction opportunities where capabilities of one component could be leveraged with those of others in a relatively seamless fashion within CREATE-AV Helios.

  14. Health Promotion & Counselling in Context of Mixedness

    DEFF Research Database (Denmark)

    Singla, Rashmi

    and ‘homogeneity’ on one hand and increasing, polarisation between us & the others and increasing ethnic diversity on the other. Despite increase in number, intermarried couples are still almost invisible as a statistical category and in psychosocial services. Both increased risk for married life disruption...... on subjectively experienced feelings and expressive behaviour, such as responses of others, ‘gaze’ to couples’ ‘visible differences’ and the societal attitudes - the external aspects are significant. Practices such as focus on the ‘fun part’ involving negotiation of gender positions, cultural and social capital....../exclusion processes in the society should be taken in consideration for health promotion, and counselling of the intermarried couples. Key words: Ethnic intermarriages, increased risks, opportunities, good practices, health promotion, integrative counselling...

  15. Considering Culturally Relevant Practices and Knowledge-Sharing When Creating an Activity-Promoting Community Research Agenda

    Science.gov (United States)

    Coppola, Angela M.; McHugh, Tara-Leigh F.

    2018-01-01

    The purpose of the article is to discuss and reflect upon a process of building relationships and conducting community consultations to co-create a relevant community-based participatory research agenda exploring Indigenous youth activity-promoting programming. Four consultations were conducted with approximately 30 community members in Edmonton,…

  16. Reduction of TIP30 in esophageal squamous cell carcinoma cells involves promoter methylation and microRNA-10b

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Wenjie, E-mail: dongwenjie200581@126.com [Department of Internal Medicine-Oncology, The First Affiliated Hospital, Zhengzhou University (China); Shen, Ruizhe; Cheng, Shidan [Department of Gastroenterology, Rui-jin Hospital, Shanghai Jiao Tong University, Shanghai (China)

    2014-10-31

    Highlights: • TIP30 expression is frequently suppressed in ESCC. • TIP30 was hypermethylated in ESCC. • Reduction of TIP30 was significantly correlated with LN metastasis. • miR-10b is a direct regulator of TIP30. - Abstract: TIP30 is a putative tumor suppressor that can promote apoptosis and inhibit angiogenesis. However, the role of TIP30 in esophageal squamous cell carcinoma (ESCC) biology has not been investigated. Immunohistochemistry was used to investigate the expression of TIP30 in 70 ESCC. Hypermethylation of TIP30 was evaluated by the methylation specific PCR (MSP) method in ESCC (tumor and paired adjacent non-tumor tissues). Lost expression of TIP30 was observed in 50 of 70 (71.4%) ESCC. 61.4% (43 of 70) of primary tumors analyzed displayed TIP30 hypermethylation, indicating that this aberrant characteristic is common in ESCC. Moreover, a statistically significant inverse association was found between TIP30 methylation status and expression of the TIP30 protein in tumor tissues (p = 0.001). We also found that microRNA-10b (miR-10b) targets a homologous DNA region in the 3′untranslated region of the TIP30 gene and represses its expression at the transcriptional level. Reporter assay with 3′UTR of TIP30 cloned downstream of the luciferase gene showed reduced luciferase activity in the presence of miR-10b, providing strong evidence that miR-10b is a direct regulator of TIP30. These results suggest that TIP30 expression is regulated by promoter methylation and miR-10b in ESCC.

  17. Materials Delivered by Member States

    International Nuclear Information System (INIS)

    1968-01-01

    The information given in this document is divided into two parts. In part I the Director General is reporting to the Members of the Agency, under Article IX. G of the Statute, the quantities of materials delivered by Members up to 30 June 1968 in compliance with requests the Agency had made under Article IX,D. Part II contains information about materials which had not been delivered by 30 June 1968 but which had been allocated, in accordance with Article XI.F.I of the Statute, to approved Agency projects for which project arrangements were in force on that date

  18. "Estudo comparativo da função erétil em pacientes portadores da forma digestiva da Doença de Chagas"

    OpenAIRE

    Valdi Camarcio Bezerra

    2003-01-01

    O objetivo deste estudo foi correlacionar as alterações causadas pela doença de Chagas no sistema nervoso autônomo e a possibilidade destas alterações provocarem disfunção erétil. Foram incluídos 60 pacientes, do sexo masculino, entre 40 e 70 anos, sendo 30 com a forma digestiva da doença de Chagas e 30 como grupo controle negativos para tripanossomíase; foram utilizados o questionário auto-aplicável do Índice Internacional de Função Erétil (IIFE) e o algoritmo de pontuação para análise e int...

  19. Not Just Fun and Games: Toy Advertising on Television Targeting Children Promotes Sedentary Play.

    Science.gov (United States)

    Potvin Kent, Monique; Velkers, Clive

    2017-10-01

    To examine the volume of television toy advertising targeting Canadian children and to determine if it promotes active or sedentary play, targets males or females more frequently, and has changed over time. Data for toy/game advertising from 27 television stations in Toronto for the month of May in 2006 and 2013 were licensed from Neilsen Media Research (Montreal, Quebec, Canada). A content analysis was performed on all ads to determine what age group and gender were targeted and whether physical or sedentary activity was being promoted. Comparisons were made between 2006 and 2013. There were 3.35 toy ads/h/children's specialty station in 2013 (a 15% increase from 2006). About 88% of toy ads promoted sedentary play in 2013, a 27% increase from 2006 levels, while toy ads promoting active play decreased by 33%. In both 2006 and 2013, a greater number of sedentary toy ads targeted males (n = 1519, May 2006; n = 2030, May 2013) compared with females (n = 914, May 2006; n = 1619, May 2013), and between 2006 and 2013, these ads increased significantly for both males and females. Future research should explore whether such advertising influences children's preferences for activities and levels of physical activity.

  20. Cooperation during cultural group formation promotes trust towards members of out-groups.

    Science.gov (United States)

    Pan, Xiaofei Sophia; Houser, Daniel

    2013-07-07

    People often cooperate with members of their own group, and discriminate against members of other groups. Previous research establishes that cultural groups can form endogenously, and that these groups demonstrate in-group favouritism. Given the presence of cultural groups, the previous literature argues that cultural evolution selects for groups that exhibit parochial altruism. The source of initial variation in these traits, however, remains uninformed. We show here that a group's economic production environment may substantially influence parochial tendencies, with groups formed around more cooperative production (CP) displaying less parochialism than groups formed around more independent production (IP) processes. Participants randomized into CP and IP production tasks formed cultural groups, and subsequently played hidden-action trust games with in-group and out-group trustees. We found CP to be associated with significantly greater sharing and exchanging behaviours than IP. In trust games, significant parochial altruism (in-group favouritism combined with out-group discrimination) was displayed by members of IP groups. By contrast, members of CP groups did not engage in either in-group favouritism or out-group discrimination. Further, we found the absence of out-group discrimination in CP to persist even following 'betrayal'. Finally, belief data suggest that members of CP are not more intrinsically generous than IP members, but rather more likely to believe that out-group trustees will positively reciprocate. Our results have important implications for anyone interested in building cooperative teams, and shed new light on connections between culture and cooperation.

  1. Fun with singing wine glasses

    Science.gov (United States)

    Boone, Christine; Galloway, Melodie; Ruiz, Michael J.

    2018-05-01

    A fun activity is presented using singing wine glasses for introductory physics students. Students tune a white wine glass and a red wine glass to as many semitones as possible by filling the glasses with the appropriate amounts of water. A smart phone app is used to measure the frequencies of equal-temperament tones. Then plots of frequency against water volume percent are made using a spreadsheet. Students can also play combinations of pitches with several glasses. A video (Ruiz 2018 Video: Singing glasses http://mjtruiz.com/ped/wineglasses/) is provided which includes an excerpt of a beautiful piece written for singing glasses and choir: Stars by Latvian composer Ēriks Ešenvalds.

  2. Sistema Computacional para Ajuste de Funções Densidade de Probabilidade

    Directory of Open Access Journals (Sweden)

    Daniel Henrique Breda Binoti

    Full Text Available RESUMO Este trabalho teve por objetivo iniciar, implementar e validar um projeto de construção de um sistema computadorizado para ajuste de funções densidade de probabilidade. O FitFD foi desenvolvido utilizando-se a linguagem de programação Java. Como ambiente de desenvolvimento foram utilizadas a IDE (Integrated Development Environment Netbeans 7.1 e a JDK 7.3 (Java Development Kit. Os testes do sistema foram realizados em ambiente Windows. Foram implementadas no sistema as seguintes funções densidade de probabilidade: Weibull (2P, 3P, 2P com dap mínimo como locação, 3P truncada, hiperbólica (2P, 3P, 2P com dap mínimo como locação, 3P truncada, log-logística (2P, 3P, 2P com dap mínimo como locação, logística generalizada, Fatigue life (2P e 3P e Frechet (2P e 3P. O sistema desenvolvido auxilia os usuários na definição e escolha da fdp que melhor atenda suas necessidades, contudo melhorias são necessárias. O projeto iniciado mostrou-se eficiente para ajustes de funções de densidade probabilidade.

  3. Integração de três conceitos: função executiva, memória de trabalho e aprendizado

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Mourão Junior

    Full Text Available O presente artigo discute o conceito de função executiva enquanto um processo de integração temporal, envolvendo funções como o ajuste preparatório, o controle inibitório e a memória de trabalho. Em seguida questiona o modelo multicomponente de Baddeley para a memória de trabalho e propõe uma nova classificação da função executiva que engloba os modelos de Fuster e de Baddeley. Finalmente revisita o conceito neurobiológico de aprendizado e sugere uma abordagem para se avaliar os déficits de aprendizagem que leve em conta a função executiva como a pedra angular do processo cognitivo.

  4. Olympic opening ceremony was a vibrant feast of fun and energy.

    Science.gov (United States)

    Crawford, Linda

    2012-08-08

    If director Danny Boyle's intention at the Olympic opening ceremony was to provide a snapshot of Britain today, he succeeded. It was an inspired feast of energy, colour and vibrancy - as well as being great fun.

  5. Comportamento agronômico de bananeira 'Prata-anã' em função do tipo de muda

    Directory of Open Access Journals (Sweden)

    Luiz Antonio Junqueira Teixeira

    2011-03-01

    Full Text Available Foi realizado um experimento de campo com bananeira 'Prata-anã', visando a avaliar o comportamento agronômico de plantas estabelecidas a partir de três tipos de mudas: convencional, micropropagadas em meio sólido e em meio líquido. A área experimental foi instalada no município de Cristais Paulista-SP (20º23'S; 47º30'W, cujo clima é caracterizado por verão chuvoso e inverno seco. Avaliaram-se o crescimento e a fenologia por meio de medidas periódicas de comprimento e diâmetro do pseudocaule das plantas até a emissão da inflorescência. A incidência de doenças (CMV e mal-do-panamá foi estimada visualmente em função da apresentação de sintomas característicos pelas plantas. As plantas originadas de mudas micropropagadas apresentaram crescimento e desenvolvimento iniciais mais vigorosos, maior precocidade e cachos mais leves do que aquelas estabelecidas com mudas convencionais. Não foram observadas diferenças significativas em relação à incidência de doenças e ao tamanho dos frutos produzidos, em função dos tipos de mudas.

  6. Serious Fun: Using Toys to Demonstrate Fluid Mechanics Principles

    Science.gov (United States)

    Saviz, Camilla M.; Shakerin, Said

    2014-01-01

    Many students have owned or seen fluids toys in which two immiscible fluids within a closed container can be tilted to generate waves. These types of inexpensive and readily available toys are fun to play with, but they are also useful for provoking student learning about fluid properties or complex fluid behavior, including drop formation and…

  7. Serious Simulations (for fun)

    DEFF Research Database (Denmark)

    Andersen, Christian Ulrik

    2006-01-01

    , their laws of physics and their rule structure not only belong to the game world. Incessantly and innovatively, they reach far beyond the game universe and into reality. The computer game today is the place where we not only escape reality, but also relate to reality – similar to the role of the movie......’Serious Simulations (for fun)’ deals with a dramatic change in the area of computer games. Computer games have throughout the past decades given us the opportunity to experience, tell stories and play in virtual, computer generated worlds. Today, however, the narratives of the computer games...... in the 20th century. They have become an important part of marketing, teaching, political activism, communication and information to the public. It is the language of the future, the language for and about the reality we are living in. The game simulations are still compelling and entertaining...

  8. Bike Skills Training in PE Is Fun, Keeps Kids Safe

    Science.gov (United States)

    Wallace, Judi Lawson; Sutton, Nancy P.

    2015-01-01

    Incorporating bike skills into the elementary- and middle-school physical education curriculum encourages students to be physically active in a fun way while also learning bike safety skills. Winston-Salem's (NC) Safe Routes to School program demonstrates how collaboration with the public schools' health and physical education program can…

  9. A significant association between BDNF promoter methylation and the risk of drug addiction.

    Science.gov (United States)

    Xu, Xuting; Ji, Huihui; Liu, Guili; Wang, Qinwen; Liu, Huifen; Shen, Wenwen; Li, Longhui; Xie, Xiaohu; Zhou, Wenhua; Duan, Shiwei

    2016-06-10

    As a member of the neurotrophic factor family, brain derived neurotrophic factor (BDNF) plays an important role in the survival and differentiation of neurons. The aim of our work was to evaluate the role of BDNF promoter methylation in drug addiction. A total of 60 drug abusers (30 heroin and 30 methylamphetamine addicts) and 52 healthy age- and gender-matched controls were recruited for the current case control study. Bisulfite pyrosequencing technology was used to determine the methylation levels of five CpGs (CpG1-5) on the BDNF promoter. Among the five CpGs, CpG5 methylation was significantly lower in drug abusers than controls. Moreover, significant associations were found between CpG5 methylation and addictive phenotypes including tension-anxiety, anger-hostility, fatigue-inertia, and depression-dejection. In addition, luciferase assay showed that the DNA fragment of BDNF promoter played a key role in the regulation of gene expression. Our results suggest that BDNF promoter methylation is associated with drug addiction, although further studies are needed to understand the mechanisms by which BDNF promoter methylation contributes to the pathophysiology of drug addiction. Copyright © 2016. Published by Elsevier B.V.

  10. Ecological occurrence of Gluconacetobacter diazotrophicus and nitrogen-fixing Acetobacteraceae members: their possible role in plant growth promotion.

    Science.gov (United States)

    Saravanan, V S; Madhaiyan, M; Osborne, Jabez; Thangaraju, M; Sa, T M

    2008-01-01

    Gluconacetobacter diazotrophicus has a long-standing history of bacterial-plant interrelationship as a symbiotic endophyte capable of fixing atmospheric nitrogen. In low nitrogen fertilized sugarcane fields it plays a significant role and its occurrence was realised in most of the sugarcane growing countries. In this mini review, the association of G. diazotrophicus with sugarcane, other crop plants and with various hosts is discussed. The factors affecting survival in the rhizosphere and the putative soil mode of transmission are emphasized. In addition, other N(2)-fixing Acetobacteraceae members, including Gluconacetobacter azotocaptans, Gluconacetobacter johannae and Swaminathania salitolerans, occurring in coffee, corn and rice plants are also covered. Lastly, the plant-growth-promoting traits identified in this group of bacteria, including N(2) fixation, phytohormone synthesis, P and Zn solubilization and biocontrol, are analysed.

  11. Does the Animal Fun program improve social-emotional and behavioural outcomes in children aged 4-6 years?

    Science.gov (United States)

    Piek, Jan P; Kane, Robert; Rigoli, Daniela; McLaren, Sue; Roberts, Clare M; Rooney, Rosanna; Jensen, Lynn; Dender, Alma; Packer, Tanya; Straker, Leon

    2015-10-01

    Animal Fun was designed to enhance motor and social development in young children. Its efficacy in improving motor skills was presented previously using a randomised controlled trial and a multivariate nested cohort design. Based on the Environmental Stress Hypothesis, it was argued that the program would also result in positive mental health outcomes, investigated in the current study. Pre-intervention scores were recorded for 511 children aged 4.83-6.17 years (M=5.42, SD=.30). Intervention and control groups were compared 6 months following intervention, and again in their first school year. Changes in teacher-rated prosocial behaviour and total difficulties were assessed using the Strengths and Difficulties Questionnaire, and data analysed using Generalised Linear Mixed Models. There was a significant improvement in prosocial behaviour of children in the intervention group six months after initial testing, which remained at 18-month follow-up. Total difficulties decreased at 6 months for the intervention group, with no change at 18 months. This effect was present only for the hyperactivity/inattention subscale. The only significant change for the control group was an increase in hyperactivity/inattention scores from pre-intervention to 18-month follow-up. The Animal Fun program appears to be effective in improving social and behavioural outcomes. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. FunCoup 4: new species, data, and visualization

    OpenAIRE

    Ogris, Christoph; Guala, Dimitri; Kaduk, Mateusz; Sonnhammer, Erik L L

    2017-01-01

    Abstract This release of the FunCoup database (http://funcoup.sbc.su.se) is the fourth generation of one of the most comprehensive databases for genome-wide functional association networks. These functional associations are inferred via integrating various data types using a naive Bayesian algorithm and orthology based information transfer across different species. This approach provides high coverage of the included genomes as well as high quality of inferred interactions. In this update of ...

  13. Do Standard Bibliometric Measures Correlate with Academic Rank of Full-Time Pediatric Dentistry Faculty Members?

    Science.gov (United States)

    Susarla, Harlyn K; Dhar, Vineet; Karimbux, Nadeem Y; Tinanoff, Norman

    2017-04-01

    The aim of this cross-sectional study was to assess the relationship between quantitative measures of research productivity and academic rank for full-time pediatric dentistry faculty members in accredited U.S. and Canadian residency programs. For each pediatric dentist in the study group, academic rank and bibliometric factors derived from publicly available databases were recorded. Academic ranks were lecturer/instructor, assistant professor, associate professor, and professor. Bibliometric factors were mean total number of publications, mean total number of citations, maximum number of citations for a single work, and h-index (a measure of the impact of publications, determined by total number of publications h that had at least h citations each). The study sample was comprised of 267 pediatric dentists: 4% were lecturers/instructors, 44% were assistant professors, 30% were associate professors, and 22% were professors. The mean number of publications for the sample was 15.4±27.8. The mean number of citations was 218.4±482.0. The mean h-index was 4.9±6.6. The h-index was strongly correlated with academic rank (r=0.60, p=0.001). For this sample, an h-index of ≥3 was identified as a threshold for promotion to associate professor, and an h-index of ≥6 was identified as a threshold for promotion to professor. The h-index was strongly correlated with the academic rank of these pediatric dental faculty members, suggesting that this index may be considered a measure for promotion, along with a faculty member's quality and quantity of research, teaching, service, and clinical activities.

  14. Significados do trabalho e do dinheiro: Quais suas funções sociais?

    Directory of Open Access Journals (Sweden)

    Sabrina Cavalcanti Barros

    2018-03-01

    Full Text Available Estudos sobre o trabalho e o dinheiro têm enfatizado a dimensão institucional desses fenômenos, destacando funções como a capacidade de interligar a satisfação das necessidades individuais e a manutenção da ordem social. Tais funções são ativadas no cotidiano dos indivíduos, sendo construídas socialmente na produção dos significados dos referidos fenômenos. Exploramos as funções que os significados do trabalho e do dinheiro cumpriram na vida dos operários da construção civil. Realizamos entrevistas semiestruturadas com 44 operários e desenvolvemos análise de conteúdo temática. Identificamos dois grandes eixos norteadores: inclusão e inserção sociais versus exclusão social e realização e sentido de utilidade versus degradação. Os resultados indicaram que as condições de trabalho precárias e a escassez de dinheiro estruturaram os modos de enfrentamento dessas realidades, na valorização dos benefícios alcançados, na naturalização e no conformismo, decorrentes da dureza e limitação de oportunidades experimentadas por esses trabalhadores. Limitações da pesquisa e sugestões são apontadas.

  15. Materials Delivered by Member States

    International Nuclear Information System (INIS)

    1962-01-01

    The information given in this document is divided into two parts. In part I the Director General is reporting to the Members of the Agency, under Article IX. G of the Statute, the quantities of materials delivered up to 30 September 1962 by Member States in compliance with requests the Agency has made under Article IX. D. Part II contains information about materials which have not yet been delivered but which have been allocated, in accordance with Article XI. F. 1 of the Statute, to approved Agency projects for which project agreements were in force on 30 September 1962. Reports on subsequent deliveries of materials and revised information about allocated but undelivered materials will be issued from time to time

  16. A Limited Evaluation of Full Scale Control Surface Deflection Drag (Have FUN)

    National Research Council Canada - National Science Library

    Reinhardt, R. B; Celi, Sean A; Geraghty, Jeffrey T; Stahl, James W; Glover, Victor J; Bowman, Geoffrey G

    2007-01-01

    The Have FUN (FUll Scale Numbers) Test Management Project was conducted at the request of the USAF TPS as an investigation into the drag caused by control surface deflection during dynamic soaring techniques...

  17. Does formal mentoring for faculty members matter? A survey of clinical faculty members.

    Science.gov (United States)

    Mylona, Elza; Brubaker, Linda; Williams, Valerie N; Novielli, Karen D; Lyness, Jeffrey M; Pollart, Susan M; Dandar, Valerie; Bunton, Sarah A

    2016-06-01

    Mentoring relationships, for all medical school faculty members, are an important component of lifelong development and education, yet an understanding of mentoring among medical school clinical faculty members is incomplete. This study examined associations between formal mentoring relationships and aspects of faculty members' engagement and satisfaction. It then explored the variability of these associations across subgroups of clinical faculty members to understand the status of mentoring and outcomes of mentoring relationships. The authors hypothesised that academic clinical faculty members currently in formal mentoring relationships experience enhanced employee engagement and satisfaction with their department and institution. Medical school faculty members at 26 self-selected USA institutions participated in the 2011-2014 Faculty Forward Engagement Survey. Responses from clinical faculty members were analysed for relationships between mentoring status and perceptions of engagement by faculty members. Of the 11 953 clinical faculty respondents, almost one-third reported having a formal mentoring relationship (30%; 3529). Most mentored faculty indicated the relationship was important (86%; n = 3027), and over three-fourths were satisfied with their mentoring experience (77%; n = 2722). Mentored faculty members across ranks reported significantly higher levels of satisfaction and more positive perceptions of their roles in the organisation. Faculty members who were not receiving mentoring reported significantly less satisfaction with their workplace environment and lower overall satisfaction. Mentored clinical faculty members have significantly greater satisfaction with their department and institution. This multi-institutional study provides evidence that fostering mentoring opportunities may facilitate faculty members' satisfaction and engagement, which, in turn, may help medical schools retain high-quality faculty staff committed to the multidimensional

  18. Xplora: making science fun!

    CERN Multimedia

    2006-01-01

    Remember those humdrum lectures in science class? Static textbook lessons have not done much to ignite excitement and interest in young children. Now the tables are turned and it is the teachers who are learning, but this time it is all about how to make science classes fun and spark the imaginations of the next generation. Xplora conference participants observing a working cloud experiment. The Xplora Conference, held at CERN from 15 to 18 June, was attended by more than 80 teachers and educators from across Europe ready to share and acquire some creative ways of teaching science. Xplora is an online reference project providing inventive techniques for teaching science in the classroom and beyond. Xplora is part of the Permanent European Resource Centre for Informal Learning (PENCIL) sponsored by the European Commission. PENCIL is comprised of 13 science centres, museums and aquariums, is partners with the University of Naples, Italy and King's College London, UK and is involved with 14 pilot projects thro...

  19. Position statement: start middle and high schools at 8:30 am or later to promote student health and learning.

    Science.gov (United States)

    Trevorrow, Tracy; Zhou, Eric S; Dietch, Jessica R; Gonzalez, Brian D

    2018-03-13

    The Society of Behavioral Medicine recommends school officials start middle and high school classes at 8:30 am or later. Such a schedule promotes students' sleep health, resulting in improvements in physical health, psychological well-being, attention and concentration, academic performance, and driving safety. In this position statement, we propose a four-tiered approach to promote later school start times for middle and high schools.

  20. The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas

    Science.gov (United States)

    Garces de los Fayos Alonso, Ines; Lagger, Sabine; Merkel, Olaf; Kenner, Lukas

    2018-01-01

    The Activator Protein-1 (AP-1) transcription factor (TF) family, composed of a variety of members including c-JUN, c-FOS and ATF, is involved in mediating many biological processes such as proliferation, differentiation and cell death. Since their discovery, the role of AP-1 TFs in cancer development has been extensively analysed. Multiple in vitro and in vivo studies have highlighted the complexity of these TFs, mainly due to their cell-type specific homo- or hetero-dimerization resulting in diverse transcriptional response profiles. However, as a result of the increasing knowledge of the role of AP-1 TFs in disease, these TFs are being recognized as promising therapeutic targets for various malignancies. In this review, we focus on the impact of deregulated expression of AP-1 TFs in CD30-positive lymphomas including Classical Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma. PMID:29597249

  1. Powernext 2002: 32 members 30% monthly growth a positive result

    International Nuclear Information System (INIS)

    2002-01-01

    Powernext SA is a Multilateral Trading Facility which organizes and warrants the transactions on the European power exchange market. This activity report presents the highlights of the market and of Powernext in 2002: evolution of prices, power consumption in France, supply and demand, power generation in France, arbitration with other markets, traded volumes, Powernext members. (J.S.)

  2. Sun Protection is Fun! A Skin Cancer Prevention Program for Preschools.

    Science.gov (United States)

    Tripp, Mary K.; Herrmann, Nancy B.; Parcel, Guy S.; Chamberlin, Robert M.; Gritz, Ellen R.

    2000-01-01

    Describes the Sun Protection is Fun! skin cancer prevention program for preschool children that features intervention methods grounded in social cognitive theory and emphasizes symbolic modeling, vicarious learning, enactive mastery experiences, and persuasion. Program components include a curriculum and teacher's guide, videos, newsletters,…

  3. Whole Grains and Food Fun in an After-School Program

    Science.gov (United States)

    Gilboy, Mary Beth

    2009-01-01

    Programs in community-based, after-school settings are ideal to teach children about healthy eating. Objectives: After completing this Whole Grains & Food Fun lesson, children will be able to: (1) list at least two benefits of eating more whole grains, (2) demonstrate skills involved in child-friendly, basic food preparation, and (3) choose a…

  4. 76 FR 26930 - Dairy Promotion and Research Program; Importer Nominations to the Dairy Promotion and Research Board

    Science.gov (United States)

    2011-05-10

    ...: AMS-DA-08-0050] Dairy Promotion and Research Program; Importer Nominations to the Dairy Promotion and... to the Dairy Production Stabilization Act of 1983 (Dairy Act), as amended, and the Dairy Promotion... importer representation, initially two members, to the National Dairy Promotion and Research Board (Dairy...

  5. Fuel for Fun: a cluster-randomized controlled study of cooking skills, eating behaviors, and physical activity of 4th graders and their families.

    Science.gov (United States)

    Cunningham-Sabo, Leslie; Lohse, Barbara; Smith, Stephanie; Browning, Ray; Strutz, Erin; Nigg, Claudio; Balgopal, Meena; Kelly, Kathleen; Ruder, Elizabeth

    2016-05-26

    Childhood obesity remains a serious concern in the United States and in many other countries. Direct experience preparing and tasting healthful foods and increasing activity during the school day are promising prevention approaches. Engaging parents and families remains an important challenge. Fuel for Fun: Cooking with Kids Plus Parents and Play is a multi-component school- and family-based intervention for 4th graders and their families intended to promote positive food and activity environments, policies and behaviors at the individual, family and school levels. This paper describes the design and evaluation plan. Four cohorts of 4th-graders and their parents from 8 schools in 2 districts in the same Northern Colorado region are participating in a 4-arm cluster randomized controlled trial. Theory-based Fuel for Fun consists of 5 components delivered over 1 school year: 1) Cooking with Kids - Colorado; an experiential classroom-based cooking and tasting curriculum, 2) Cafeteria Connections; cafeteria-based reinforcements of classroom food experiences using behavioral economic strategies, 3) SPARK active recess; a playground intervention to engage children in moderate to vigorous activity, 4) Fuel for Fun Family; multi-element supports targeting parents to reinforce the 3 school-based components at home, and 5) About Eating; an online interactive program for parents addressing constructs of eating competence and food resource management. Outcomes include child and parent measures of fruit and vegetable preferences and intake, cooking, physical activity, sedentary behaviors and attitudes. School level data assess lunch plate waste and physical activity at recess. In-depth diet and accelerometry assessments are collected with a subsample of parent-child dyads. Data are collected at baseline, immediately post-intervention at 7 months, and at 12 month follow-up. We anticipate recruiting 1320-1584 children and their parents over the length of the project. The Fuel

  6. FunCoup 4: new species, data, and visualization.

    Science.gov (United States)

    Ogris, Christoph; Guala, Dimitri; Sonnhammer, Erik L L

    2018-01-04

    This release of the FunCoup database (http://funcoup.sbc.su.se) is the fourth generation of one of the most comprehensive databases for genome-wide functional association networks. These functional associations are inferred via integrating various data types using a naive Bayesian algorithm and orthology based information transfer across different species. This approach provides high coverage of the included genomes as well as high quality of inferred interactions. In this update of FunCoup we introduce four new eukaryotic species: Schizosaccharomyces pombe, Plasmodium falciparum, Bos taurus, Oryza sativa and open the database to the prokaryotic domain by including networks for Escherichia coli and Bacillus subtilis. The latter allows us to also introduce a new class of functional association between genes - co-occurrence in the same operon. We also supplemented the existing classes of functional association: metabolic, signaling, complex and physical protein interaction with up-to-date information. In this release we switched to InParanoid v8 as the source of orthology and base for calculation of phylogenetic profiles. While populating all other evidence types with new data we introduce a new evidence type based on quantitative mass spectrometry data. Finally, the new JavaScript based network viewer provides the user an intuitive and responsive platform to further evaluate the results. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  7. A-DaGO-Fun: an adaptable Gene Ontology semantic similarity-based functional analysis tool.

    Science.gov (United States)

    Mazandu, Gaston K; Chimusa, Emile R; Mbiyavanga, Mamana; Mulder, Nicola J

    2016-02-01

    Gene Ontology (GO) semantic similarity measures are being used for biological knowledge discovery based on GO annotations by integrating biological information contained in the GO structure into data analyses. To empower users to quickly compute, manipulate and explore these measures, we introduce A-DaGO-Fun (ADaptable Gene Ontology semantic similarity-based Functional analysis). It is a portable software package integrating all known GO information content-based semantic similarity measures and relevant biological applications associated with these measures. A-DaGO-Fun has the advantage not only of handling datasets from the current high-throughput genome-wide applications, but also allowing users to choose the most relevant semantic similarity approach for their biological applications and to adapt a given module to their needs. A-DaGO-Fun is freely available to the research community at http://web.cbio.uct.ac.za/ITGOM/adagofun. It is implemented in Linux using Python under free software (GNU General Public Licence). gmazandu@cbio.uct.ac.za or Nicola.Mulder@uct.ac.za Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  8. Promotion rates for assistant and associate professors in obstetrics and gynecology.

    Science.gov (United States)

    Rayburn, William F; Schrader, Ronald M; Fullilove, Anne M; Rutledge, Teresa L; Phelan, Sharon T; Gener, Yolanda

    2012-05-01

    To estimate promotion rates of physician faculty members in obstetrics and gynecology during the past 30 years Data were collected annually by the Association of American Medical Colleges from every school between 1980 and 2009 for first-time assistant and associate professors to determine whether and when they were promoted. Data for full-time physician faculty were aggregated by decade (1980-1989, 1990-1999, 2000-2009). Faculty were included if they remained in academia for 10 years after beginning in rank. Data were analyzed by constructing estimated promotion curves and extracting 6-year and 10-year promotion rates. The 10-year promotion rates (adjusted for attrition) declined significantly for assistant professors from 35% in 1980-1989 to 32% in 1990-1999 to 26% in 2000-2009 (P<.001), and for associate professors from 37% to 32% to 26%, respectively (P<.005). These declines most likely resulted from changes in faculty composition. The most recent 15 years saw a steady increase in the proportion of entry-level faculty who were women (now 2:1) and primarily on the nontenure track. The increasing number of faculty in general obstetrics and gynecology had lower promotion probabilities than those in the subspecialties (odds ratio 0.16; P<.001). Female faculty on the nontenure track had lower promotion rates than males on the nontenure track, males on the tenure track, and females on the tenure track (odds ratio 0.8 or less; P<.01). A decline in promotion rates during the past 30 years may be attributable to changes in faculty composition. II.

  9. Efficacy of Cognitive-Functional (Cog-Fun) Occupational Therapy Intervention Among Children With ADHD: An RCT.

    Science.gov (United States)

    Hahn-Markowitz, Jeri; Berger, Itai; Manor, Iris; Maeir, Adina

    2016-09-16

    To examine the efficacy of a Cognitive-Functional (Cog-Fun) intervention for children with ADHD. Random allocation of 107 children to study or control groups preceded 10 parent-child weekly Cog-Fun sessions emphasizing executive strategy training in games and daily activities. Controls received treatment after crossover. Study participants were followed up 3 months post-treatment. Outcomes included parent/teacher ratings of executive functions, ADHD symptoms, and parent ratings of quality of life. Eight children withdrew prior to treatment. All children in both groups who began treatment completed it. Mixed effects ANOVA revealed significant Time × Group interaction effects on all parent-reported outcomes. Treatment effects were moderate to large, replicated after crossover in the control group and not moderated by medication. Parent-reported treatment gains in the study group were maintained at follow-up. No significant Time × Group interaction effects were found on teacher outcomes. Cog-Fun occupational therapy (OT) intervention shows positive context-specific effects on parent, but not teacher, ratings. © The Author(s) 2016.

  10. What do health-promoting schools promote?

    DEFF Research Database (Denmark)

    Simovska, Venka

    2012-01-01

    -promotion interventions. Directly or indirectly the articles reiterate the idea that health promotion in schools needs to be linked with the core task of the school – education, and to the values inherent to education, such as inclusion, democracy, participation and influence, critical literacy and action competence......Purpose – The editorial aims to provide a brief overview of the individual contributions to the special issue, and a commentary positioning the contributions within research relating to the health-promoting schools initiative in Europe. Design/methodology/approach – The members of the Schools...... for Health in Europe Research Group were invited to submit their work addressing processes and outcomes in school health promotion to this special issue of Health Education. Additionally, an open call for papers was published on the Health Education web site. Following the traditional double blind peer...

  11. ONLINE SCAMS: TAKING THE FUN OUT OF THE INTERNET

    OpenAIRE

    Pradeep Kumar Puram; Mukesh Kaparthi; Aditya Krishna Haas Rayaprolu

    2011-01-01

    The fun of using the Internet has become sour due to the various scams taking place day in and day out, all around the world. Internet users are being trapped around every corner and their credit card information is being siphoned, all due to the presence of these online scams. This paper looks in depth into a few of these scams, and explores a solution to counter this menace.

  12. “Pick-up Lines”: A Fun Way to Facilitate Learning Microbiological Concepts

    Directory of Open Access Journals (Sweden)

    Thomas Edison E. dela Cruz

    2014-05-01

    Full Text Available Learning microbiology can be made fun by writing funny lines related to microbiology. Students were tasked to create their own pick-up lines and explain these based on their understanding of the basic concepts in microbiology.

  13. Fun with Foodella: A Pilot Study for Determining the Efficacy of a 2nd Grade Nutrition and Physical Activity Curriculum

    Science.gov (United States)

    Winter, Elizabeth M.; Stluka, Suzanne; Wells, Karlys; Wey, Howard; Kemmer, Teresa M.

    2012-01-01

    Fun with Foodella is a nutrition and physical activity workbook designed for elementary-aged youth. The objective was to determine if the Fun with Foodella program increased participant preference for fruit, vegetables, low-fat dairy products, and physical activity. Four intervention (53 students) and four control (68 students) schools…

  14. 12 CFR 925.30 - Readmission to membership.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Readmission to membership. 925.30 Section 925.30 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOME LOAN BANK MEMBERS AND HOUSING ASSOCIATES MEMBERS OF THE BANKS Reacquisition of Membership § 925.30 Readmission to membership. (a) In...

  15. Organizational culture in nursing schools in Turkey: faculty members' perspectives.

    Science.gov (United States)

    Kantek, F; Baykal, U

    2009-09-01

    Among the benefits of examining an organization's culture are the opportunity to understand the basic mechanisms of the institutional and structural procedures, to determine the need for change and to ensure the development and satisfaction of the faculty members. To determine the perceptions of faculty members of organizational culture at nursing schools in Turkey and to examine different perceptions in relation to demographic variables. The study was conducted with 180 faculty members from seven nursing schools in state universities located in different geographical regions of Turkey that granted permission for the study. All faculty members in these schools with at least 1 year of institutional experience were included in the research. No sampling was required. A demographic information form and an organizational culture scale were used as data collection materials. The organizational culture scale contains 30 items and resolves the organizational culture in three dimensions. The minimum score obtained was 1 and the maximum was 5. The mean score for faculty members' in total scale was 3.40 (SD = 0.68), while it was 3.26 (SD = 0.77) for the management style dimension, 3.39 (SD = 0.73) for the organizational commitment/relations dimension and 3.68 (SD = 0.73) for the student-oriented dimension. There was no statistical difference between the perception of organizational culture and work experience at the institution, marital status or educational status, but there were differences in age, number of years in the profession and academic titles. It was found that strong perceptions have been established in nursing schools in regard to student-oriented practices, and that groups consisting of senior academic personnel and experienced academicians are considered to be better at perceiving the importance of the organizational culture. The administrators are recommended to promote policies to enhance the participation in decision-making processes and regularly monitor

  16. TYCTWD Programs Strive to Make Science Educational and Fun | Poster

    Science.gov (United States)

    By Carolynne Keenan, Contributing Writer Joseph Barchi, Jr, Ph.D., calls teaching “the noblest and most important profession.” So it makes sense that Barchi, senior scientist and head of the Glycoconjugate and NMR Section, Chemical Biology Laboratory, Center for Cancer Research, NCI at Frederick, would encourage his lab to offer a fun, educational program at Take Your Child to

  17. Generational Attitudes toward Workplace Fun and Their Relationship to Job Satisfaction

    Science.gov (United States)

    Attebery, Esther

    2017-01-01

    Purpose: The purpose of this quantitative study was to examine attitudes toward workplace fun and overall job satisfaction of baby boomer, Generation X, and millennial staff employees at a Christian university in California, and determine if there is a predictive relationship between them. Conceptual Framework: The framework was developed from…

  18. Materiales en Marcha para el Esfuerzo Bilingue--Bicultural (Materials on the March for the Promotion of Bilingualism/Biculturalism), December 1972.

    Science.gov (United States)

    San Diego City Schools, CA.

    This newsletter seeks to promote the concept of bilingual-cultural education. Among its articles are "Political Power and Bilingualism,""Saturday Fun for Joao and Maria,""Student Selected Geography Texts," and "To Become Aware of One's Reality." Included is a list of distributors of educational materials in Spanish and Portuguese. Some of the…

  19. Enterovirus 71 induces autophagy by regulating has-miR-30a expression to promote viral replication.

    Science.gov (United States)

    Fu, Yuxuan; Xu, Wentao; Chen, Deyan; Feng, Chunhong; Zhang, Li; Wang, Xiaohui; Lv, Xiaowen; Zheng, Nan; Jin, Yu; Wu, Zhiwei

    2015-12-01

    Enterovirus 71 (EV71), the etiological agent of hand-foot-and-mouth disease, has increasingly become a public health challenge around the world. Previous studies reported that EV71 infection can induce autophagic machinery to enhance viral replication in vitro and in vivo, but did not address the underlying mechanisms. Increasing evidence suggests that autophagy, in a virus-specific manner, may function to degrade viruses or facilitate viral replication. In this study, we reported that EV71 infection of human epidermoid carcinoma (Hep2) and African green monkey kidney cells (Vero) induced autophagy, which is beneficial for viral replication. Our investigation of the mechanisms revealed that EV71 infection resulted in the reduction of cellular miR-30a, which led to the inhibition of Beclin-1, a key autophagy-promoting gene that plays important roles at the early phase of autophagosome formation. We provided further evidence that by modulating cellular miR-30a level through either overexpression or inhibition, one can inhibit or promote EV71 replication, respectively, through regulating autophagic activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. A New Architecture for FUN3D on Modern HPC Systems, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of this project is to refactor NASA's FUN3D computation fluid dynamic (CFD) simulation code to enable it to take full advantage of accelerator hardware...

  1. Stromal-dependent tumor promotion by MIF family members.

    Science.gov (United States)

    Mitchell, Robert A; Yaddanapudi, Kavitha

    2014-12-01

    Solid tumors are composed of a heterogeneous population of cells that interact with each other and with soluble and insoluble factors that, when combined, strongly influence the relative proliferation, differentiation, motility, matrix remodeling, metabolism and microvessel density of malignant lesions. One family of soluble factors that is becoming increasingly associated with pro-tumoral phenotypes within tumor microenvironments is that of the migration inhibitory factor family which includes its namesake, MIF, and its only known family member, D-dopachrome tautomerase (D-DT). This review seeks to highlight our current understanding of the relative contributions of a variety of immune and non-immune tumor stromal cell populations and, within those contexts, will summarize the literature associated with MIF and/or D-DT. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Dying in the Hospital: Perspectives of family members.

    Science.gov (United States)

    Dose, Ann Marie; Carey, Elise C; Rhudy, Lori M; Chiu, Yichen; Frimannsdottir, Katrin; Ottenberg, Abigale L; Koenig, Barbara A

    2015-01-01

    Although most patients express a preference to die at home, many (over 30 percent) still die in hospital. This study's purpose was to explore the experience of hospital death from the perspective of patients' family members. interviews were conducted with family members of patients who had died at hospitals affiliated with a large tertiary referral centre in the United States. Content analysis was used to analyze findings. We interviewed 30 family members by phone. Themes were arranged by time frame: before death, time of death, and after death. Families do not interpret clinical cues leading up to death in the same way healthcare providers do; families need clear and direct explanations from providers. Clinicians should assess patient and family understandings of prognosis and communicate clearly and directly. Family members value being with their loved one at the time of death, and they value spending time with the body after death; this should be facilitated in clinical practice.

  3. Food & Fun op de boerderij : Consumenten komen graag op de boerderij

    NARCIS (Netherlands)

    Stil, L.; PPO Akkerbouw, Groene Ruimte en Vollegrondsgroente

    2009-01-01

    Een Food- & Fun-boerderij geeft consumenten een goed gevoel en daarom komen ze er graag. Ze komen om te genieten van het buiten zijn en omdat ze er wat kunnen leren. De ervaring van het boerenleven zorgt voor een stapje uit de dagelijkse werkelijkheid met rust, ruimte, ritme en natuur van de

  4. Utilização da função pearson tipo V, Weibull e hiperbólica para modelagem da distribuição de diâmetros

    Directory of Open Access Journals (Sweden)

    Daniel Henrique Breda Binoti

    2013-09-01

    Full Text Available Objetivou-se neste estudo avaliar a eficiência da função log-Pearson tipo V para a descrição da estrutura diamétrica de povoamentos equiâneos de eucaliptos, bem como propor um modelo de distribuição diamétrica utilizando essa função. A modelagem realizada pela função log-Pearson tipo V foi comparada com a modelagem realizada com a função Weibull e hiperbólica. Para isso utilizou-se dados de parcelas permanentes de eucalipto, localizadas na região centro oeste do estado de Minas Gerais. A função Pearson tipo V foi testada em três diferentes configurações, com três e dois parâmetros, e tendo o parâmetro de locação substituído pelo diâmetro mínimo da parcela. A aderência das funções aos dados foi comprovada pela aplicação do teste Kolmogorov-Sminorv (K-S. Todos os ajustes apresentaram aderência aos dados pelo teste KS. As funções Weibull e hiperbólica apresentaram desempenho superior ao demonstrado pela função Pearson tipo V.

  5. Cognitive-Functional (Cog-Fun) Dyadic Intervention for Children with ADHD and Their Parents: Impact on Parenting Self-Efficacy.

    Science.gov (United States)

    Hahn-Markowitz, Jeri; Berger, Itai; Manor, Iris; Maeir, Adina

    2018-03-01

    The family context of children with ADHD plays a role in intervention outcomes, especially when parents are involved in treatment. Parental participation in evidence-based treatment for ADHD may play a role in improving their own parenting self-efficacy (PSE) as well as child outcomes. This study examined the impact of Cognitive-Functional (Cog-Fun) intervention in occupational therapy (OT) for school-aged children with ADHD, on PSE. In this randomized controlled trial with crossover design, 107 children were allocated to intervention and waitlist control groups. Intervention participants (n = 50) received Cog-Fun after baseline assessment and waitlist controls (n = 49) received treatment 3 months later. Intervention participants received 3-month follow-up assessment. Treatment included 10 parent-child Cog-Fun weekly sessions. PSE was assessed with the Tool to measure Parenting Self-Efficacy (TOPSE). All children who began treatment completed it. Mixed ANOVA revealed significant Time x Group interaction effects on TOPSE scales of Play and Enjoyment, Control, Self-Acceptance, Knowledge and Learning and Total score, which showed significant improvement with moderate treatment effects for the intervention group. Results were replicated in the control group after crossover. The findings of this study suggest that Cog-Fun OT intervention may be effective for improving aspects of PSE among parents of children with ADHD.

  6. Make Celebrations Fun, Healthy, and Active: 10 Tips to Creating Healthy, Active Events

    Science.gov (United States)

    United States Department of Agriculture 10 tips Nutrition Education Series MyPlate MyWins Based on the Dietary Guidelines for Americans Make celebrations fun, healthy, and active Eating healthy and being physically active can be a ...

  7. Função Poética e Televisão

    Directory of Open Access Journals (Sweden)

    Anna Maria Balogh

    1990-10-01

    Full Text Available Ao empreendermos uma rápida usca nos guardados da memória, verificamos a existência de conceitos arraigados no tocante ao que se considera artístico". Alguns dos conceitos de "artisticidade" revelam vinculações estreitas com as funções "estética" e "poética".

  8. Estresse crônico melhora a função miocárdica sem alterar a atividade do canal-L para Ca+2 em ratos

    Directory of Open Access Journals (Sweden)

    Thiago Bruder-Nascimento

    2012-10-01

    Full Text Available FUNDAMENTO: O estresse crônico está associado à remodelação cardíaca; entretanto, os mecanismos permanecem a ser descobertos. OBJETIVO: A proposta deste estudo foi testar a hipótese de que o estresse crônico promove disfunção cardíaca associada a depressão da atividade do canal-L para Ca2+. M MÉTODOS: Ratos Wistar machos com 30 dias de idade (70 - 100 g foram distribuídos dentro de dois grupos: controle (C e estresse crônico (St. O estresse consistiu na imobilização durante 15 semanas, cinco vezes por semana, 1 h por dia. A função cardíaca foi avaliada pela performance do ventrículo esquerdo por meio do ecocardiograma e pelo músculo papilar ventricular isolado. A função do músculo papilar foi avaliada em condição basal e com manobras inotrópicas, como: pós-pausa e elevação na concentração extracelular de Ca2+, na presença ou ausência de um bloqueador específico de canal-L para Ca2+. RESULTADOS: O estresse ficou caracterizado por hipertrofia das glândulas adrenais, aumento nos níveis de corticosterona circulante e por hipertensão arterial. Ainda, o estresse crônico gerou hipertrofia ventricular esquerda. O estresse crônico foi capaz de melhorar a resposta no músculo papilar para manobras inotrópicas positivas. A melhora de função não esteve associada com o canal-L para Ca2+. CONCLUSÃO: O estresse produziu hipertrofia cardíaca; entretanto, nos estudos de músculo papilar isolado, as manobras inotrópicas positivas potencializaram a função cardíaca em ratos estressados, sem o envolvimento do canal-L para Ca2+. Assim os mecanismos responsáveis permanecem incertos para alterações no influxo de Ca2+.

  9. Radiation Coupling with the FUN3D Unstructured-Grid CFD Code

    Science.gov (United States)

    Wood, William A.

    2012-01-01

    The HARA radiation code is fully-coupled to the FUN3D unstructured-grid CFD code for the purpose of simulating high-energy hypersonic flows. The radiation energy source terms and surface heat transfer, under the tangent slab approximation, are included within the fluid dynamic ow solver. The Fire II flight test, at the Mach-31 1643-second trajectory point, is used as a demonstration case. Comparisons are made with an existing structured-grid capability, the LAURA/HARA coupling. The radiative surface heat transfer rates from the present approach match the benchmark values within 6%. Although radiation coupling is the focus of the present work, convective surface heat transfer rates are also reported, and are seen to vary depending upon the choice of mesh connectivity and FUN3D ux reconstruction algorithm. On a tetrahedral-element mesh the convective heating matches the benchmark at the stagnation point, but under-predicts by 15% on the Fire II shoulder. Conversely, on a mixed-element mesh the convective heating over-predicts at the stagnation point by 20%, but matches the benchmark away from the stagnation region.

  10. Associação entre funções da via auditiva eferente e genotoxicidade em adultos jovens Association between auditory pathway efferent functions and genotoxicity in young adults

    Directory of Open Access Journals (Sweden)

    Andressa Boer Fronza

    2011-02-01

    Full Text Available Funções da via auditiva eferente incluem a modulação das células ciliadas externas, proteção contra ruído e melhora na detecção da fonte sonora em ambientes ruidosos. Genotoxicidade são danos ao DNA. OBJETIVOS: Analisar associação entre funções da via auditiva eferente com marcadores genotóxicos. Adicionalmente, considerou-se tabagismo e gênero como principais variáveis intervenientes. MATERIAL E MÉTODO: Estudo prospectivo-clínico, quantitativo, transversal, contemporâneo. Foi realizada uma análise da função da via auditiva eferente e indicadores de genotoxicidade em 60 voluntários adultos jovens. RESULTADOS: Idade média dos voluntários foi de 24,86±3,68 anos; 30 do gênero masculino e 30 do gênero feminino, 15 de cada gênero tabagistas e 15 não tabagistas; indivíduos do gênero masculino tabagistas apresentaram maior ocorrência de efeito de supressão das EOAEPDs nas frequências de 2000 e 6000Hz na orelha do lado esquerdo; mulheres tabagistas apresentaram maior prevalência de queixa de dificuldade de ouvir em ambiente ruidoso; indivíduos tabagistas e mulheres apresentaram maiores danos ao DNA; indivíduos com queixas de dificuldade auditiva e zumbido apresentaram maiores índices de genotoxicidade. CONCLUSÕES: Em adultos jovens normo-ouvintes que referem queixas relacionadas às funções da via auditiva eferente, como zumbido e dificuldade auditiva, já é possível observar associação com genotoxicidade considerando interações entre gênero e tabagismo.Efferent auditory pathways modulate outer hair cells of the cochlea, protect against noise, and improve the detection of sound sources in noisy environments. Genotoxicity is DNA damage. AIM: To study the association between auditory pathway efferent functions with genotoxic markers. The study also considered smoking and gender as two main variables. METHODS: A prospective-clinical, quantitative, cross-sectional, contemporary study. The function of

  11. Calcium-aluminum-rich inclusions with fractionation and unknown nuclear effects (FUN CAIs)

    DEFF Research Database (Denmark)

    Krot, Alexander N.; Nagashima, Kazuhide; Wasserburg, Gerald J.

    2014-01-01

    We present a detailed characterization of the mineralogy, petrology, and oxygen isotopic compositions of twelve FUN CAIs, including C1 and EK1-4-1 from Allende (CV), that were previously shown to have large isotopic fractionation patterns for magnesium and oxygen, and large isotopic anomalies...

  12. Zeros da função zeta de Riemann e o teorema dos números primos

    OpenAIRE

    Oliveira, Willian Diego [UNESP

    2013-01-01

    We studied various properties of the Riemann’s zeta function. Three proofs of the Prime Number Theorem were provides. Classical results on zero-free region of the zeta function, as well as their relation to the error term in the Prime Number Theorem, were studied in details Estudamos várias propriedades da função zeta de Riemann. Três provas do Teorema dos Números Primos foram fornecidas. Resultados clássicos sobre regiões livres de zeros da função zeta, bem como sua relação com o termo do...

  13. Uma análise comparativa de funções MDX nos servidores Analysis Services e Mondrian

    OpenAIRE

    ALBUQUERQUE, Erivam Anselmo de

    2013-01-01

    A MultiDimensional eXpression (MDX) é uma linguagem de consulta para processamento analítico de dados ou On-line Analytical Processing (OLAP). Apesar de esta linguagem ser usada pela maioria dos servidores OLAP, esta não é um padrão de direito. Portanto, tem-se pouca (ou nenhuma) garantia de que as funções MDX usadas por um servidor OLAP também possam ser usadas em outros servidores. Neste contexto, de forma a comparar as funções MDX de um servidor OLAP de código aberto e outro de código fech...

  14. Sandy Point Fun Run: A Context for Understanding and Using Scale

    Science.gov (United States)

    Roche, Anne

    2013-01-01

    In the middle years of school, it is important that mathematics is challenging, engaging and focuses on worthwhile mathematics. In this article, Anne Roche describes a lesson that seemed to have all three of these characteristics, as students grappled with issues of scale to create a fun run, given a range of challenging mathematical constraints.…

  15. Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway.

    Science.gov (United States)

    Qin, Xian; Li, Changsheng; Guo, Tao; Chen, Jing; Wang, Hai-Tao; Wang, Yi-Tao; Xiao, Yu-Sha; Li, Jun; Liu, Pengpeng; Liu, Zhi-Su; Liu, Quan-Yan

    2017-10-19

    Infection with the hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC). The osmoregulatory transcription factor nuclear factor of activated T-cells 5 (NFAT5) has been shown to play an important role in the development of many types of human cancers. The role of NFAT5 in HBV-associated HCC has never previously been investigated. We compared expression profiles of NFAT5, DARS2 and miR-30e-5p in HCC samples, adjacent nontumor tissues and different hepatoma cell lines by quantitative real-time polymerase chain reaction and /or Western blot. Clinical data of HCC patients for up to 80 months were analyzed. The regulatory mechanisms upstream and convergent downstream pathways of NFAT5 in HBV-associated HCC were investigated by ChIP-seq, MSP, luciferase report assay and bioinformation anaylsis. We first found that higher levels of NFAT5 expression predict a good prognosis, suggesting that NFAT5 is a potential tumor-suppressing gene, and verified that NFAT5 promotes hepatoma cell apoptosis and inhibits cell growth in vitro. Second, our results showed that HBV could suppress NFAT5 expression by inducing hypermethylation of the AP1-binding site in the NFAT5 promoter in hepatoma cells. In addition, HBV also inhibited NFAT5 through miR-30e-5p targeted MAP4K4, and miR-30e-5p in turn inhibited HBV replication. Finally, we demonstrated that NFAT5 suppressed DARS2 by directly binding to its promoter. DARS2 was identified as an HCC oncogene that promotes HCC cell cycle progression and inhibits HCC cell apoptosis. HBV suppresses NFAT5 through the miR-30e-5p/mitogen-activated protein kinase (MAPK) signaling pathway upstream of NFAT5 and inhibits the NFAT5 to enhance HCC tumorigenesis via the downstream target genes of DARS2.

  16. Observação do desenvolvimento de linguagem e funções auditiva e visual em lactentes

    Directory of Open Access Journals (Sweden)

    Lima Maria Cecília Marconi Pinheiro

    2004-01-01

    Full Text Available OBJETIVO: Investigar o desenvolvimento da linguagem e das funções auditiva e visual em lactentes de creche, a partir da avaliação realizada por educadores. MÉTODOS: Foram avaliados 115 lactentes, nos anos de 1998 a 2001, usuários de uma creche da área da saúde de uma universidade do Estado de São Paulo. Foi utilizado o "Protocolo da Observação do Desenvolvimento de Linguagem e das Funções Auditiva e Visual", com 39 provas no total, para a avaliação dos lactentes de 3 até 12 meses de idade. A aplicação desse Protocolo foi feita pelas educadoras da creche, devidamente treinadas. Utilizou-se o teste de Qui-quadrado ou Exato de Fisher. O nível de significância adotado foi de 5%. RESULTADOS: Os lactentes apresentaram um padrão diferente no desenvolvimento da linguagem quanto ao início do balbucio e das primeiras palavras, bem como na função visual, quanto à imitação e uso de jogos gestuais e de seguir ordem com uso de gestos. CONCLUSÕES: O ambiente creche propicia condições para um outro padrão de desenvolvimento de linguagem e das funções auditiva e visual. Ações de prevenção na creche devem integrar as áreas de saúde e educação num objetivo comum.

  17. Fuel for Fun: a cluster-randomized controlled study of cooking skills, eating behaviors, and physical activity of 4th graders and their families

    Directory of Open Access Journals (Sweden)

    Leslie Cunningham-Sabo

    2016-05-01

    Full Text Available Abstract Background Childhood obesity remains a serious concern in the United States and in many other countries. Direct experience preparing and tasting healthful foods and increasing activity during the school day are promising prevention approaches. Engaging parents and families remains an important challenge. Fuel for Fun: Cooking with Kids Plus Parents and Play is a multi-component school- and family-based intervention for 4th graders and their families intended to promote positive food and activity environments, policies and behaviors at the individual, family and school levels. This paper describes the design and evaluation plan. Methods/Design Four cohorts of 4th-graders and their parents from 8 schools in 2 districts in the same Northern Colorado region are participating in a 4-arm cluster randomized controlled trial. Theory-based Fuel for Fun consists of 5 components delivered over 1 school year: 1 Cooking with Kids - Colorado; an experiential classroom-based cooking and tasting curriculum, 2 Cafeteria Connections; cafeteria-based reinforcements of classroom food experiences using behavioral economic strategies, 3 SPARK active recess; a playground intervention to engage children in moderate to vigorous activity, 4 Fuel for Fun Family; multi-element supports targeting parents to reinforce the 3 school-based components at home, and 5 About Eating; an online interactive program for parents addressing constructs of eating competence and food resource management. Outcomes include child and parent measures of fruit and vegetable preferences and intake, cooking, physical activity, sedentary behaviors and attitudes. School level data assess lunch plate waste and physical activity at recess. In-depth diet and accelerometry assessments are collected with a subsample of parent-child dyads. Data are collected at baseline, immediately post-intervention at 7 months, and at 12 month follow-up. We anticipate recruiting 1320–1584 children and their

  18. Emotional disorders in pairs of patients and their family members during and after ICU stay.

    Directory of Open Access Journals (Sweden)

    Renata Rego Lins Fumis

    Full Text Available INTRODUCTION: Patients and family members undergo different experiences of suffering from emotional disorders during ICU stay and after ICU discharge. The purpose of this study was to compare the incidence of anxiety, depression and post-traumatic stress disorder (PTSD symptoms in pairs (patient and respective family member, during stay at an open visit ICU and at 30 and 90-days post-ICU discharge. We hypothesized that there was a positive correlation with the severity of symptoms among pairs and different patterns of suffering over time. METHODS: A prospective study was conducted in a 22-bed adult general ICU including patients with >48 hours stay. The Hospital Anxiety and Depression Scale (HADS was completed by the pairs (patients/respective family member. Interviews were made by phone at 30 and 90-days post-ICU discharge using the Impact of Event Scale (IES and the HADS. Multivariate models were constructed to predict IES score at 30 days for patients and family members. RESULTS: Four hundred and seventy one family members and 289 patients were interviewed in the ICU forming 184 pairs for analysis. Regarding HADS score, patients presented less symptoms than family members of patients who survived and who deceased at 30 and 90-days (p<0.001. However, family members of patients who deceased scored higher anxiety and depression symptoms (p = 0.048 at 90-days when compared with family members of patients who survived. Patients and family members at 30-days had a similar IES score, but it was higher in family members at 90-days (p = 0.019. For both family members and patients, age and symptoms of anxiety and depression during ICU were the major determinants for PTSD at 30-days. CONCLUSIONS: Anxiety, depression and PTSD symptoms were higher in family members than in the patients. Furthermore, these symptoms in family members persisted at 3 months, while they decreased in patients.

  19. Fun with maths and physics: brain teasers tricks illusions

    CERN Document Server

    Perelman, Yakov

    2013-01-01

    Fun with Maths and Physics details a large number of intriguing physics experiments, entertaining mathematics problems, and amazing optical illusions.The book’s main objective is to arouse the reader’s scientific imagination, teach him to think in a scientific manner, and create in his mind a variety of associations between physical knowledge and a large number of real daily life observations.Immensely instructive and entertaining, it has been one of the best sellers in Russia during the first part of last century.

  20. Application of FUN3D Solver for Aeroacoustics Simulation of a Nose Landing Gear Configuration

    Science.gov (United States)

    Vatsa, Veer N.; Lockard, David P.; Khorrami, Mehdi R.

    2011-01-01

    Numerical simulations have been performed for a nose landing gear configuration corresponding to the experimental tests conducted in the Basic Aerodynamic Research Tunnel at NASA Langley Research Center. A widely used unstructured grid code, FUN3D, is examined for solving the unsteady flow field associated with this configuration. A series of successively finer unstructured grids has been generated to assess the effect of grid refinement. Solutions have been obtained on purely tetrahedral grids as well as mixed element grids using hybrid RANS/LES turbulence models. The agreement of FUN3D solutions with experimental data on the same size mesh is better on mixed element grids compared to pure tetrahedral grids, and in general improves with grid refinement.

  1. MODEL PENGEMBANGAN PERMAINAN FUN HOCKEY PADA SISWA KELAS XI SMA NEGERI 1 BAWANG KECAMATAN BAWANG KABUPATEN BATANG TAHUN 2014.

    Directory of Open Access Journals (Sweden)

    Wahyu Putri Vembriana Dewi

    2015-07-01

    Full Text Available The purpose of this study was to produce a model of the development of the game Fun Hockey in the XI student class of SMAN 1 Bawang, Bawang Subdistrict, Batang. The method used is the development of Borg & Gall, namely: (1 to analyze the products that will be developed that are obtained from the information collection, including field observations and study of literature, (2 develop a form of initial product model game Fun Hockey, (3 expert validation test which uses a physical education expert (hockey skills and learning experts physical education in high school, as well as small scale test, using questionnaires and consultations later in the analysis, (4 the first product revision, revision of the product based on the results of expert evaluation and testing of small-scale (12 students, (5 field trials (28 students, (6 the revision of the final product is done based on the results of field trials, (7 the outcome Fun Hockey game for students of XI class generated through the revision of field trials. From the data on the differences can concluded that the Fun Hockey Game model development can be implemented as an alternative model for students learning physical education XI class SMAN 1 Bawang, Bawang Subdistrict, Batang.

  2. Promoting Global Health

    Directory of Open Access Journals (Sweden)

    Margaret A. Winker, MD

    2015-11-01

    Full Text Available The Editor-in-Chief of the International Journal of MCH and AIDS (IJMA is a member of the World Association of Medical Editors (WAME. The Editorial Board of IJMA believes it is important that the statement on promoting global health and this accompanying editorial is brought to the attention of our readers. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

  3. Promotion through Marketing Channels : The Case of Kosovo

    Directory of Open Access Journals (Sweden)

    MSc. Hidajet Karaxha

    2016-01-01

    Full Text Available In order for a product to be put in the hands of the customer, requires a mechanism which is called distribution channel and which enables the connection between the consumer and producer. One of the many strategies applied by Kosovar companies for the involvement of the members of the channel is also the promotion through distribution channels. Therefore, the strategies which involve the members of the channel have a higher probability to be positively accepted by the members of the channel, when they are part of a general program of supporting the needs of the producers. The process of realizing a marketing strategy of a company does not concise only of achieving specific goals of production during the realization of the promotion phase, but it also requires identifying the target market and achieving it. The purpose of this paper is to review the promotion strategy of distribution channels, which emphasize the support by the members of the channel, initiated by the producers through cooperative advertisements, promotional salaries, slotting taxes, incentives, promotions in markets and also special promotional agreements. The theoretical and practical side of the study are very important, especially regarding to new theoretical and practical views in the study context. Besides the theoretical contribution that will be offered by this paper, there will also be interesting findings in the practical aspect where through this paper, the owners, managers, firms will be able to understand the role and importance of promotion through distribution channels. Knowing that there are only few studies offered in this field, this paper offers help for everyone interested in this field. This paper contains empirical data collected by questionnaires and interviews.

  4. A socio-musical analysis of Ayo Bankole's choral music: Fun Mi N ...

    African Journals Online (AJOL)

    ... diverse African elements and major features of African music are present in the melody, rhythm and harmony of the vocal work. The paper concluded that Fun Mi N'Ibeji contained both elements of traditional Nigerian music and Western classical music which are employed in expressing the traditional beliefs of the Yoruba ...

  5. Effects of cognitive-behavioral treatment for weight loss in family members.

    Science.gov (United States)

    Rossini, Raffaella; Moscatiello, Simona; Tarrini, Giulietta; Di Domizio, Silvia; Soverini, Valentina; Romano, Andreina; Mazzotti, Arianna; Dalle Grave, Riccardo; Marchesini, Giulio

    2011-11-01

    The possibility that lifestyle changes may be shared by the family members of subjects with obesity attending cognitive-behavioral treatment (CBT) for weight loss has been scarcely evaluated. The purpose of this study was to measure the changes in body weight, lifestyle habits, and stage of change toward physical activity in the family members of 149 subjects with overweight/obesity enrolled into a weekly group CBT for weight management in the years 2007-2008. 230 adult (aged >18 years) family members (129 spouses, 72 children (43 female, 29 male), 29 with a different family relationship) completed a self-administered questionnaire at baseline and soon after the end of the completion of their relatives' program (approximately 6 months later). The questionnaire consisted of qualitative information regarding food choices, estimation of energy and food intake, self-report of height and weight, and motivation toward physical activity. At baseline, self-reported body mass index was normal in 115 cases, in the range 25 to 29.9 in 80 and ≥30 in 35. Following CBT of their relatives, the family members significantly reduced their average daily energy intake (-232 kcal/day; Pfood choices revealed a reduced average daily amount of energy from dressings (-40 kcal, Pbread (-58 kcal, P<0.001), breakfast biscuits (-23 kcal, P=0.005), chocolate (-7 kcal, P=0.024), and nonalcoholic beverages (fruit juices and carbonated drinks; -10 kcal; P=0.013), whereas fruit consumption was increased (+10 kcal; P=0.023). There was also a shift in the stage of change toward exercising. Body mass index changes of family members and CBT subjects were significantly correlated, mainly within spouses. In conclusion, CBT for weight loss positively influences the lifestyle habits of family members of participants, reducing energy intake and promoting a more favorable attitude toward physical activity. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  6. FunSAV: predicting the functional effect of single amino acid variants using a two-stage random forest model.

    Directory of Open Access Journals (Sweden)

    Mingjun Wang

    Full Text Available Single amino acid variants (SAVs are the most abundant form of known genetic variations associated with human disease. Successful prediction of the functional impact of SAVs from sequences can thus lead to an improved understanding of the underlying mechanisms of why a SAV may be associated with certain disease. In this work, we constructed a high-quality structural dataset that contained 679 high-quality protein structures with 2,048 SAVs by collecting the human genetic variant data from multiple resources and dividing them into two categories, i.e., disease-associated and neutral variants. We built a two-stage random forest (RF model, termed as FunSAV, to predict the functional effect of SAVs by combining sequence, structure and residue-contact network features with other additional features that were not explored in previous studies. Importantly, a two-step feature selection procedure was proposed to select the most important and informative features that contribute to the prediction of disease association of SAVs. In cross-validation experiments on the benchmark dataset, FunSAV achieved a good prediction performance with the area under the curve (AUC of 0.882, which is competitive with and in some cases better than other existing tools including SIFT, SNAP, Polyphen2, PANTHER, nsSNPAnalyzer and PhD-SNP. The sourcecodes of FunSAV and the datasets can be downloaded at http://sunflower.kuicr.kyoto-u.ac.jp/sjn/FunSAV.

  7. Manufacturing leisure - Innovations in happiness, well-being and fun

    OpenAIRE

    Pantzar, Mika; Shove, Elizabeth

    2005-01-01

    Kulutus ja vapaa-ajan talous ovat nousseet useissa länsimaissa elinkeinopoliittisen keskustelun huomion kohteeksi viime vuosina. Talouden kasvu on nähty yhä enemmän tapahtuvan ns. elämystalouden ja viihdeteollisuuden virittämänä. Manufacturing leisure - Innovations in happiness, well-being and fun lähestyy vapaa-ajan klusteria kuluttajien vapaa-ajan käytäntöjen näkökulmasta. Saksalaiset, englantilaiset ja suomalaiset tutkijat pyrkivät vastaamaan muun muassa seuraaviin kysymyksiin: · Minkälais...

  8. The TIP30 protein complex, arachidonic acid and coenzyme A are required for vesicle membrane fusion.

    Directory of Open Access Journals (Sweden)

    Chengliang Zhang

    Full Text Available Efficient membrane fusion has been successfully mimicked in vitro using artificial membranes and a number of cellular proteins that are currently known to participate in membrane fusion. However, these proteins are not sufficient to promote efficient fusion between biological membranes, indicating that critical fusogenic factors remain unidentified. We have recently identified a TIP30 protein complex containing TIP30, acyl-CoA synthetase long-chain family member 4 (ACSL4 and Endophilin B1 (Endo B1 that promotes the fusion of endocytic vesicles with Rab5a vesicles, which transport endosomal acidification enzymes vacuolar (H⁺-ATPases (V-ATPases to the early endosomes in vivo. Here, we demonstrate that the TIP30 protein complex facilitates the fusion of endocytic vesicles with Rab5a vesicles in vitro. Fusion of the two vesicles also depends on arachidonic acid, coenzyme A and the synthesis of arachidonyl-CoA by ACSL4. Moreover, the TIP30 complex is able to transfer arachidonyl groups onto phosphatidic acid (PA, producing a new lipid species that is capable of inducing close contact between membranes. Together, our data suggest that the TIP30 complex facilitates biological membrane fusion through modification of PA on membranes.

  9. New offer for our members

    CERN Document Server

    Staff Association

    2018-01-01

    Evolution 2, your specialist for Outdoor Adventures Be it for a ski lesson, a parachute jump or for a mountain bike descent, come live an unforgettable experience with our outdoor specialists. Benefit from a 10 % discount on all activities: Offer is open to SA members and their family members living in the same household, upon presentation of the membership card. Offer available for all bookings made between 1 June 2018 and 30 May 2019. Offer available on all the Evoltion2 sites. A wide range of summer and winter activities. More information on http://evolution2.com/ Contact and reservation : +33 (0)4.50.02.63.35 management@evolution2.com

  10. 45 CFR 2520.30 - What capacity-building activities may AmeriCorps members perform?

    Science.gov (United States)

    2010-10-01

    ... AmeriCorps members perform should enhance the mission, strategy, skills, and culture, as well as systems... that are included in, or consistent with, your Corporation-approved grant application. (b) Examples of...

  11. Promotion and Fast Food Demand

    OpenAIRE

    Timothy J. Richards; Luis Padilla

    2009-01-01

    Many believe that fast food promotion is a significant cause of the obesity epidemic in North America. Industry members argue that promotion only reallocates brand shares and does not increase overall demand. We study the effect of fast food promotion on market share and total demand by estimating a discrete / continuous model of fast food restaurant choice and food expenditure that explicitly accounts for both spatial and temporal determinants of demand. Estimates are obtained using a unique...

  12. 27 CFR 6.96 - Consumer promotions.

    Science.gov (United States)

    2010-04-01

    ... OF THE TREASURY LIQUORS âTIED-HOUSEâ Exceptions § 6.96 Consumer promotions. (a) Coupons. The act by an industry member of furnishing to consumers coupons which are redeemable at a retail establishment... such coupons; and (2) An industry member may not reimburse a retailer for more than the face value of...

  13. Technology-based intervention for healthy lifestyle promotion in Italian adolescents.

    Science.gov (United States)

    Fraticelli, Federica; Marchetti, Daniela; Polcini, Francesco; Mohn, Angelika Anna; Chiarelli, Francesco; Fulcheri, Mario; Vitacolonna, Ester

    2016-01-01

    Healthy lifestyle promotion programs are essential to prevent metabolic diseases such as obesity and diabetes. Adolescents could represent the ideal target population especially using serious web games. To test the improvement of knowledge about healthy nutrition in adolescents and to analyze participants' enjoyment in playing the web game "Gustavo in Gnam's Planet" in comparison with a leisure web game. Sixty-five adolescents were engaged in three supervised group sessions. Measures about healthy food knowledge and games' enjoyment were collected during the three stages of assessment. After playing Gustavo in Gnam's Planet, participants significantly improved their knowledge on a healthy diet, compared to the recreational web games; whereas the level of fun experienced while playing the recreational and the educational games was not significantly different. Gustavo in Gnam's Planet is an important promising tool, with entertainment property, to promote a healthy lifestyle in Italian adolescents.

  14. Nucleopolis for promoting the nuclear excellence of the Normandy region

    International Nuclear Information System (INIS)

    2016-01-01

    Nucleopolis is the Norman economic pole dedicated to nuclear energy, nuclear medicine and nuclear safety, it gathers about 70 enterprises whatever their sizes, research laboratories and teaching or training units. Nucleopolis was founded in 2009 with the economic development of the region as a unique purpose. Nucleopolis will ease the access of its members to local, national and international markets through actions of networking and by promoting innovations and skill development. Nucleopolis proposes to its members a series of services around 4 departments: Nucleo'Network to promote networking between the members themselves and between the members and major contractors; Nucleo'Business to propose assistance in national and international business; Nucleo'Competence to propose adequate training to its members to upgrade their skills and Nucleo'Innovation to foster collaborative work between its members on innovative projects. (A.C.)

  15. Processo e organização do trabalho: origem, funções e questionamento atual do taylorismo-fordismo

    OpenAIRE

    Telles, Luiz Carlos da Silva

    1982-01-01

    Trata da origem, funções e questionamento da organização científica do trabalho, especificamente, do taylorismo-fordismo. Discute algumas das atuais formas de alteração da organização do trabalho ao mesmo tempo em que mostra a expansão e generalização do taylorismo-fordismo. Aborda as origens e as funções do taylorismo-fordismo como associadas a determinada conjuntura e etapa do processo de trabalho capitalista. Procura inserir a organização científica do trabalho no processo geral das transf...

  16. FunGene: the functional gene pipeline and repository.

    Science.gov (United States)

    Fish, Jordan A; Chai, Benli; Wang, Qiong; Sun, Yanni; Brown, C Titus; Tiedje, James M; Cole, James R

    2013-01-01

    Ribosomal RNA genes have become the standard molecular markers for microbial community analysis for good reasons, including universal occurrence in cellular organisms, availability of large databases, and ease of rRNA gene region amplification and analysis. As markers, however, rRNA genes have some significant limitations. The rRNA genes are often present in multiple copies, unlike most protein-coding genes. The slow rate of change in rRNA genes means that multiple species sometimes share identical 16S rRNA gene sequences, while many more species share identical sequences in the short 16S rRNA regions commonly analyzed. In addition, the genes involved in many important processes are not distributed in a phylogenetically coherent manner, potentially due to gene loss or horizontal gene transfer. While rRNA genes remain the most commonly used markers, key genes in ecologically important pathways, e.g., those involved in carbon and nitrogen cycling, can provide important insights into community composition and function not obtainable through rRNA analysis. However, working with ecofunctional gene data requires some tools beyond those required for rRNA analysis. To address this, our Functional Gene Pipeline and Repository (FunGene; http://fungene.cme.msu.edu/) offers databases of many common ecofunctional genes and proteins, as well as integrated tools that allow researchers to browse these collections and choose subsets for further analysis, build phylogenetic trees, test primers and probes for coverage, and download aligned sequences. Additional FunGene tools are specialized to process coding gene amplicon data. For example, FrameBot produces frameshift-corrected protein and DNA sequences from raw reads while finding the most closely related protein reference sequence. These tools can help provide better insight into microbial communities by directly studying key genes involved in important ecological processes.

  17. FunGene: the Functional Gene Pipeline and Repository

    Directory of Open Access Journals (Sweden)

    Jordan A. Fish

    2013-10-01

    Full Text Available Ribosomal RNA genes have become the standard molecular markers for microbial community analysis for good reasons, including universal occurrence in cellular organisms, availability of large databases, and ease of rRNA gene region amplification and analysis. As markers, however, rRNA genes have some significant limitations. The rRNA genes are often present in multiple copies, unlike most protein-coding genes. The slow rate of change in rRNA genes means that multiple species sometimes share identical 16S rRNA gene sequences, while many more species share identical sequences in the short 16S rRNA regions commonly analyzed. In addition, the genes involved in many important processes are not distributed in a phylogenetically coherent manner, potentially due to gene loss or horizontal gene transfer.While rRNA genes remain the most commonly used markers, key genes in ecologically important pathways, e.g., those involved in carbon and nitrogen cycling, can provide important insights into community composition and function not obtainable through rRNA analysis. However, working with ecofunctional gene data requires some tools beyond those required for rRNA analysis. To address this, our Functional Gene Pipeline and Repository (FunGene; http://fungene.cme.msu.edu/ offers databases of many common ecofunctional genes and proteins, as well as integrated tools that allow researchers to browse these collections and choose subsets for further analysis, build phylogenetic trees, test primers and probes for coverage, and download aligned sequences. Additional FunGene tools are specialized to process coding gene amplicon data. For example, FrameBot produces frameshift-corrected protein and DNA sequences from raw reads while finding the most closely related protein reference sequence. These tools can help provide better insight into microbial communities by directly studying key genes involved in important ecological processes.

  18. 30 years of Physics Education Research at the University of Washington

    Science.gov (United States)

    Shaffer, Peter S.

    2017-01-01

    Over the past 30 years, members of the UW Physics Education Group have examined student learning in courses serving a wide range of populations. Most of the focus has been on elementary, middle, and high school teachers and students in introductory university physics courses, but more recently, the effort has expanded to include physics majors in upper-division courses on quantum mechanics and electrodynamics. In general, the group has taken a practical approach that focuses on identifying instructional strategies that are effective at promoting conceptual understanding and student reasoning ability. Examples will be drawn from across these courses to illustrate common themes and connections.

  19. Offers for our members

    CERN Multimedia

    Staff Association

    2017-01-01

    Summer is here, enjoy our offers for the aquatic parcs! Walibi : Tickets "Zone terrestre": 24 € instead of 30 €. Access to Aqualibi: 5 € instead of 6 € on presentation of your SA member ticket. Free for children under 100 cm. Car park free. * * * * * Aquaparc : Day ticket: – Children: 33 CHF instead of 39 CHF – Adults : 33 CHF instead of 49 CHF Bonus! Free for children under 5.

  20. Offers for our members

    CERN Multimedia

    Staff Association

    2017-01-01

    Summer is coming, enjoy our offers for the aquatic parcs! Walibi : Tickets "Zone terrestre": 24 € instead of 30 €. Access to Aqualibi: 5 € instead of 6 € on presentation of your SA member ticket. Free for children under 100 cm. Car park free. * * * * * Aquaparc : Day ticket: – Children: 33 CHF instead of 39 CHF – Adults : 33 CHF instead of 49 CHF Bonus! Free for children under 5.

  1. 17 CFR 200.70 - Business promotions.

    Science.gov (United States)

    2010-04-01

    ... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.70 Business promotions. A member must not engage in any other business, employment or vocation while in office, nor may he ever use the... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Business promotions. 200.70...

  2. Where in the World Is Ronald McDonald? Involving Families in Geographic Fun!

    Science.gov (United States)

    Mater, Marty

    2017-01-01

    A Family Geography Night (FGN) kit can be used to bring families together, teach about the world, give parents the opportunity to share their beliefs, and participate in the educational system while having fun! Geography is an essential element of twenty-first-century education. More than just maps, geography is the interaction of cultures,…

  3. IN MY OPINION: Physics is fun - for whom?

    Science.gov (United States)

    Allday, Jonathan

    1998-09-01

    (modified) Punch cartoon. Marcie and Linus are discussing life: Marcie `Thank you for the Chocolate Sundae, Linus' Linus `You're welcome... Maybe we can do it again sometime?' Marcie `I don't think so... I don't find you very interesting.' Linus, wistfully and leaning against a tree - `Physics....' This cartoon the students find funny. The fact that the study of physics should be a block to a meaningful relationship seems to strike a chord with them. It takes them by surprise that physicists have a real life. Now I realize that any teacher having a real life often takes students by surprise. I remember visiting my mother's infants school when I was a sixth-former and the kids there found it unbelievable that Mrs Allday should have a son. Teachers, you see, cease to exist the minute the students walk out of the classroom. However, physics and its practitioners seem to be especially branded in this way. From time to time I show videos to my students. Well chosen ones (so I think) that reflect modern developments and show physicists enjoying what they are doing. One such tape shows the reaction to the first pictures coming down from the newly repaired Hubble Space Telescope. The control room is filled with whoops, delighted cheering and general bouncing up and down with enthusiasm. This always raises a laugh. However, one can tell that they are being laughed at, not with. Another tape is about the comet strike on Jupiter. The narrator spends some time talking with Gene and Carolyn Shoemaker (two of the discoverers of the comet) - a married team of astronomers. You can see that their married life in part revolves round their joint love of astronomy and physics. I have overheard comments like `can you imagine the breakfast conversations?' Why do students find it so difficult to imagine that physicists in real life have fun doing physics? Pondering this I have come to the conclusion that they do not see enough teachers having fun teaching the subject. Perhaps with all the time we

  4. For fun and profit a history of the free and open source software revolution

    CERN Document Server

    Tozzi, Christopher

    2017-01-01

    In the 1980s, there was a revolution with far-reaching consequences -- a revolution to restore software freedom. In the early 1980s, after decades of making source code available with programs, most programmers ceased sharing code freely. A band of revolutionaries, self-described "hackers," challenged this new norm by building operating systems with source code that could be freely shared. In For Fun and Profit, Christopher Tozzi offers an account of the free and open source software (FOSS) revolution, from its origins as an obscure, marginal effort by a small group of programmers to the widespread commercial use of open source software today. Tozzi explains FOSS's historical trajectory, shaped by eccentric personalities -- including Richard Stallman and Linus Torvalds -- and driven both by ideology and pragmatism, by fun and profit. Tozzi examines hacker culture and its influence on the Unix operating system, the reaction to Unix's commercialization, and the history of early Linux development. He describes ...

  5. Estimativa da área foliar de nabo forrageiro em função de dimensões foliares

    Directory of Open Access Journals (Sweden)

    Alberto Cargnelutti Filho

    2012-01-01

    Full Text Available O objetivo deste trabalho foi desenvolver um modelo para estimar a área foliar de nabo forrageiro (Raphanus sativus L. var. oleiferus Metzg determinada por fotos digitais, em função do comprimento, ou da largura e/ou do produto comprimento vezes largura da folha. Aos 76 dias após a semeadura, foram coletadas 557 folhas da haste principal de 92 plantas, sendo mensurados o comprimento (C e a largura (L de cada folha, e calculado o produto comprimento × largura (C×L. Após, determinou-se a área foliar (Y, por meio do método de fotos digitais. Do total de folhas, separaram-se, aleatoriamente, 450 folhas para a construção de modelos do tipo quadrático, potência e linear de Y em função de C, da L, e/ou de C×L. 107 folhas foram usadas para a validação dos modelos. O modelo do tipo potência da área foliar obtida por meio do método de fotos digitais (Ŷ=0,6843x0,9221, R²=0,9862 em função do produto comprimento × largura é adequado para estimar a área foliar de nabo forrageiro.

  6. Monkey Bites among US Military Members, Afghanistan, 2011

    Science.gov (United States)

    Baker, Katheryn A.

    2012-01-01

    Bites from Macaca mulatta monkeys, native to Afghanistan, can cause serious infections. To determine risk for US military members in Afghanistan, we reviewed records for September–December 2011. Among 126 animal bites and exposures, 10 were monkey bites. Command emphasis is vital for preventing monkey bites; provider training and bite reporting promote postexposure treatment. PMID:23017939

  7. Kid-Friendly Veggies and Fruits: 10 Tips for Making Healthy Food Choices More Fun for Children

    Science.gov (United States)

    ... Set up a pizza-making station in the kitchen. Use whole-wheat English muffins, bagels, or pita ... veggies or fruits into a fun shape or design. 5 fruity peanut butterfly Start with carrot sticks ...

  8. Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1 in Drosophila

    Directory of Open Access Journals (Sweden)

    Renkawitz-Pohl Renate

    2008-06-01

    Full Text Available Abstract Background Metal-responsive transcription factor 1 (MTF-1, which binds to metal response elements (MREs, plays a central role in transition metal detoxification and homeostasis. A Drosophila interactome analysis revealed two candidate dMTF-1 interactors, both of which are related to the small regulatory protein Dumpy-30 (Dpy-30 of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. Results Constitutive expression of the stronger interactor, Dpy-30L1 (CG6444, in transgenic flies inhibits MTF-1 activity and results in elevated sensitivity to Cd(II and Zn(II, an effect that could be rescued by co-overexpression of dMTF-1. Electrophoretic mobility shift assays (EMSA suggest that Dpy-30L1 interferes with the binding of MTF-1 to its cognate MRE binding site. Dpy-30L1 is expressed in the larval brain, gonads, imaginal discs, salivary glands and in the brain, testes, ovaries and salivary glands of adult flies. Expression of the second interactor, Dpy-30L2 (CG11591, is restricted to larval male gonads, and to the testes of adult males. Consistent with these findings, dpy-30-like transcripts are also prominently expressed in mouse testes. Targeted gene disruption by homologous recombination revealed that dpy-30L1 knockout flies are viable and show no overt disruption of metal homeostasis. In contrast, the knockout of the male-specific dpy-30L2 gene results in male sterility, as does the double knockout of dpy-30L1 and dpy-30L2. A closer inspection showed that Dpy-30L2 is expressed in elongated spermatids but not in early or mature sperm. Mutant sperm had impaired motility and failed to accumulate in sperm storage organs of females. Conclusion Our studies help to elucidate the physiological roles of the Dumpy-30 proteins, which are conserved from yeast to humans and typically act in concert with

  9. Descrição da distribuição diamétrica de sistemas agrossilvipastoris utilizando as funções Weibull e hiperbólica

    Directory of Open Access Journals (Sweden)

    Daniel Henrique Breda Binoti

    2012-04-01

    Full Text Available Foram objetivos deste estudo ajustar e avaliar diferentes formas da função Weibull e hiperbólica para descrição da estrutura diamétrica de sistemas agrossilvipastoris. O componente florestal foi estabelecido com clones de híbridos de eucalipto no espaçamento 10 x 4 m, visando à produção de madeira para energia e serraria. Nas entrelinhas houve o plantio de culturas anuais, como o arroz no primeiro ano e a soja no segundo. A partir do ano seguinte ocorreu a formação de pastagens de braquiária, manejadas para engorda de gado de corte. Testaram-se as duas funções com três parâmetros, dois parâmetros e parâmetro de locação como diâmetro mínimo e truncada à direita. A aderência da função aos dados foi avaliada pelo teste de Kolmogorov-Smirnorv. As funções também foram avaliadas pela Soma de Quadrados de Desvios (SQD e pela análise gráfica entre valores observados e estimados. Os resultados indicaram a possibilidade do uso das funções para descrição da distribuição diamétrica de povoamentos desbastados.

  10. Avaliação neuropsicológica das funções executivas: considerações metodológicas Neuropsychological assessment of executive functions: methodological questions

    Directory of Open Access Journals (Sweden)

    Amer Cavalheiro Hamdan

    2009-01-01

    Full Text Available O interesse pelo estudo das funções executivas tem crescido nos últimos anos. O objetivo deste artigo é revisar algumas questões metodológicas e conceituais relacionadas à avaliação neuropsicológica das funções executivas. As principais limitações e dicotomias relacionadas às funções executivas são apresentadas e a importância de um modelo teórico que fundamente os instrumentos de avaliação e suas interpretações clinicas analisada. Conclui-se que as evidências provenientes da investigação das funções executivas ainda não permitem a compreensão satisfatória desses processos. Sugere-se, a adoção de um modelo específico para o estudo das funções executivas.The article aims to review methodological and conceptual issues related to neuropsychological assessment of executive functions. The main limitations and dichotomies of current studies related to executive functions are presented and the importance of theoretical support to validate the instruments and their clinical interpretation are discussed. There is still the need of additional evidences on executive functions that allow a complete understanding of all the processes involved. Finally, it is suggested the adoption of a specific model that may guide the study of the executive functions.

  11. "Yes! We Are Playing a Game, and It's Going to Be Fun!"

    Science.gov (United States)

    Barrett, Kelly

    2012-01-01

    Games are for playing, more often than not playing a game is a social experience, it is fun, and we all enjoy playing games. Play and playing are ways in which we learn, so how often are games part of the normal activity of the mathematics classroom? The answer, in most cases, has to be--not often. Is it that games just don't seem to fulfil the…

  12. Health-promoting conversations-A novel approach to families experiencing critical illness in the ICU environment.

    Science.gov (United States)

    Hollman Frisman, Gunilla; Wåhlin, Ingrid; Orvelius, Lotti; Ågren, Susanna

    2018-02-01

    To identify and describe the outcomes of a nurse-led intervention, "Health-promoting conversations with families," regarding family functioning and well-being in families with a member who was critically ill. Families who have a critically ill family member in an intensive care unit face a demanding situation, threatening the normal functioning of the family. Yet, there is a knowledge gap regarding family members' well-being during and after critical illness. The study used a qualitative inductive-descriptive design. Eight families participated in health-promoting conversations aimed to create a context for change related to the families' identified problems and resources. Fifteen qualitative interviews were conducted with 18 adults who participated in health-promoting conversations about a critical illness in the family. Eight participants were patients (six men, two women) and 10 were family members (two male partners, five female partners, one mother, one daughter, one female grandchild). The interviews were analysed by conventional content analysis. Family members experienced strengthened togetherness, a caring attitude and confirmation through health-promoting conversations. The caring and calming conversations were appreciated despite the reappearance of exhausting feelings. Working through the experience and being confirmed promoted family well-being. Health-promoting conversations were considered to be healing, as the family members take part in sharing each other's feelings, thoughts and experiences with the critical illness. Health-promoting conversations could be a simple and effective nursing intervention for former intensive care patients and their families in any cultural context. © 2017 John Wiley & Sons Ltd.

  13. Promoting physical activity among youth through community-based prevention marketing.

    Science.gov (United States)

    Bryant, Carol A; Courtney, Anita H; McDermott, Robert J; Alfonso, Moya L; Baldwin, Julie A; Nickelson, Jen; McCormack Brown, Kelli R; Debate, Rita D; Phillips, Leah M; Thompson, Zachary; Zhu, Yiliang

    2010-05-01

    Community-based prevention marketing (CBPM) is a program planning framework that blends community-organizing principles with a social marketing mind-set to design, implement, and evaluate public health interventions. A community coalition used CBPM to create a physical activity promotion program for tweens (youth 9-13 years of age) called VERB Summer Scorecard. Based on the national VERB media campaign, the program offered opportunities for tweens to try new types of physical activity during the summer months. The VERB Summer Scorecard was implemented and monitored between 2004 and 2007 using the 9-step CBPM framework. Program performance was assessed through in-depth interviews and a school-based survey of youth. The CBPM process and principles used by school and community personnel to promote physical activity among tweens are presented. Observed declines may become less steep if school officials adopt a marketing mind-set to encourage youth physical activity: deemphasizing health benefits but promoting activity as something fun that fosters spending time with friends while trying and mastering new skills. Community-based programs can augment and provide continuity to school-based prevention programs to increase physical activity among tweens.

  14. Justice and care: decision making by medical school student promotions committees.

    Science.gov (United States)

    Green, Emily P; Gruppuso, Philip A

    2017-06-01

    The function of medical school entities that determine student advancement or dismissal has gone largely unexplored. The decision making of 'academic progress' or student promotions committees is examined using a theoretical framework contrasting ethics of justice and care, with roots in the moral development work of theorists Kohlberg and Gilligan. To ascertain promotions committee members' conceptualisation of the role of their committee, ethical orientations used in member decision making, and student characteristics most influential in that decision making. An electronic survey was distributed to voting members of promotions committees at 143 accredited allopathic medical schools in the USA. Descriptive statistics were calculated and data were analysed by gender, role, institution type and class size. Respondents included 241 voting members of promotions committees at 55 medical schools. Respondents endorsed various promotions committee roles, including acting in the best interest of learners' future patients and graduating highly qualified learners. Implementing policy was assigned lower importance. The overall pattern of responses did not indicate a predominant orientation toward an ethic of justice or care. Respondents indicated that committees have discretion to take individual student characteristics into consideration during deliberations, and that they do so in practice. Among the student characteristics with the greatest influence on decision making, professionalism and academic performance were paramount. Eighty-five per cent of participants indicated that they received no training. Promotions committee members do not regard orientations of justice and care as being mutually exclusive and endorse an array of statements regarding the committee's purpose that may conflict with one another. The considerable variance in the influence of student characteristics and the general absence of committee member training indicate a need for clear delineation of the

  15. A percepção de competências dos gestores desportivos em função da experiência profissional

    Directory of Open Access Journals (Sweden)

    Paula Maria Batista

    2016-03-01

    Full Text Available Resumo Este estudo teve como propósito identificar se a experiência profissional influencia o modo como os gestores municipais valorizam as suas funções e a percepção de tempo que nelas despendem. Os participantes foram 50 gestores que preencheram um questionário. Os procedimentos de análise usados foram as medidas descritivas básicas, a análise multivariada para variáveis dependentes e o coeficiente de correlação de Pearson. Os resultados indicaram uma interação significativa dos fatores anos na função e na organização na valorização das funções e percepção de tempo despendido no seu exercício. O fator experiência revelou influenciar de forma significativa o nível da percepção da importância na dimensão lecionação/docência e do tempo despendido nas dimensões lecionação/docência e marketing.

  16. Fun Seeking and Reward Responsiveness Moderate the Effect of the Behavioural Inhibition System on Coping-Motivated Problem Gambling.

    Science.gov (United States)

    Keough, Matthew T; Wardell, Jeffrey D; Hendershot, Christian S; Bagby, R Michael; Quilty, Lena C

    2017-09-01

    Gray's Reinforcement Sensitivity Theory (RST) predicts that the Behavioral Inhibition System (BIS) may relate to coping-motivated problem gambling, given its central role in anxiety. Studies examining the BIS-problem gambling association, however, are mixed. The revised RST posits that the Behavioral Approach System (BAS) may moderate the effect of the BIS on coping-motivated problem gambling. A concurrently strong BAS may highlight the negatively reinforcing effects of gambling, which may strengthen coping motives and increase gambling-related harms. We examined these interactive effects to clarify the moderators and mediators of the negative reinforcement pathway to problem gambling. Data came from a larger investigation of problem gambling among individuals with mood disorders. All participants (N = 275) met criteria for a lifetime depressive or bipolar disorder. During a two-day assessment, participants completed a diagnostic assessment and self-reports. Mediated moderation path analysis showed positive indirect effects from the BIS to problem gambling via coping motives at high, but not at low, levels of BAS-Reward Responsiveness and BAS-Fun Seeking. Enhancement motives were also found to mediate the associations of BAS-Fun Seeking and BAS-Drive with problem gambling. Reward Responsiveness and Fun Seeking facets of the BAS may strengthen coping gambling motives within the mood disorders.

  17. Intraoperative monitoring technician: a new member of the surgical team.

    Science.gov (United States)

    Brown, Molly S; Brown, Debra S

    2011-02-01

    As surgery needs have increased, the traditional surgical team has expanded to include personnel from radiology and perfusion services. A new surgical team member, the intraoperative monitoring technician, is needed to perform intraoperative monitoring during procedures that carry a higher risk of central and peripheral nerve injury. Including the intraoperative monitoring technician on the surgical team can create challenges, including surgical delays and anesthesia care considerations. When the surgical team members, including the surgeon, anesthesia care provider, and circulating nurse, understand and facilitate this new staff member's responsibilities, the technician is able to perform monitoring functions that promote the smooth flow of the surgical procedure and positive patient outcomes. Copyright © 2011 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  18. Agreement on the privileges and immunities of the Agency. Acceptances by Member States

    International Nuclear Information System (INIS)

    1995-10-01

    The list of Member States shows the 65 Members which, by 30 September 1995, had accepted the Agreement on the Privileges and Immunities of the International Atomic Energy Agency, as provided for in Section 38 thereof

  19. Agreement on the privileges and immunities of the Agency. Acceptances by Member States

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The list of Member States shows the 65 Members which, by 30 September 1995, had accepted the Agreement on the Privileges and Immunities of the International Atomic Energy Agency, as provided for in Section 38 thereof.

  20. HealthLines: Quick Tips for Seasonal Health, Safety and Fun... "Ah, when the sun beats down…"

    Science.gov (United States)

    ... Current Issue Past Issues HealthLines: Quick Tips for Seasonal Health, Safety and Fun Past Issues / Spring 2007 ... and protect against reflected UV radiation (from sand, water, or snow). UV radiation ... and stress fractures. Remember safety gear. Depending on the sport, ...

  1. Meritocracia, burocracia e cultura Brasileira: indicações aos cargos e funções de confiança no IFTO

    OpenAIRE

    Coelho, Elainy Cristina da Silva

    2015-01-01

    Historicamente, no Brasil, o preenchimento de cargos e funções de confiança é um tema que tem gerado muitas discussões e inquietações no âmbito da administração pública, em virtude, principalmente, das implicações do poder de discricionariedade do nomeador. Nesse sentido, esse trabalho objetivou discutir no âmbito da burocracia, cultura brasileira e meritocracia o preenchimento de cargos de direção (CD) e funções gratificadas (FG) na Reitoria do Instituto Federal de Educação, Ciência e Tecnol...

  2. Rendimento e qualidade de sementes de arroz irrigado em função da adubação com boro

    OpenAIRE

    LEITE, Ricardo Figueiredo Cavalheiro

    2008-01-01

    O boro é um nutriente essencial para as plantas. Suas funções estão envolvidas com o crescimento celular e o desenvolvimento da flor. Na floração, a deficiência do micronutriente reduz a macho-fertilidade em função do prejuízo à microesporogênese e ao crescimento do tubo polínico. Neste trabalho, objetivou-se definir as fases de maior sensibilidade da cultura, com o intuito de identificar épocas apropriadas para a aplicação de tratamentos corretivos de boro. A aplicação do boro, na forma de b...

  3. Rendimento e qualidade de sementes de arroz irrigado em função da adubação com boro

    OpenAIRE

    Leite, Ricardo Figueiredo Cavalheiro; Schuch, Luis Osmar Braga; Amaral, Ademir dos Santos; Tavares, Lizandro Ciciliano

    2011-01-01

    O boro é um nutriente essencial para as plantas. Suas funções estão envolvidas com o crescimento celular e o desenvolvimento da flor. Na fase reprodutiva, a deficiência do micronutriente reduz a macho-fertilidade em função do prejuízo à microesporogênese e ao crescimento posterior do tubo polínico. Neste trabalho, objetivou-se avaliar o efeito da aplicação de boro, sobre as características agronômicas e a qualidade fisiológica das sementes de arroz produzidas. A aplicação do boro, na forma de...

  4. Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

    Science.gov (United States)

    Richter, Antje M.; Haag, Tanja; Walesch, Sara; Herrmann-Trost, Peter; Marsch, Wolfgang C.; Kutzner, Heinz; Helmbold, Peter; Dammann, Reinhard H.

    2013-01-01

    Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. RASSFs are a family of tumor suppressors that are frequently inactivated by promoter hypermethylation in various cancers. We studied CpG island promoter hypermethylation in MCC of RASSF2, RASSF5A, RASSF5C and RASSF10 by combined bisulfite restriction analysis (COBRA) in MCC samples and control tissue. We found RASSF2 to be methylated in three out of 43 (7%), RASSF5A in 17 out of 39 (44%, but also 43% in normal tissue), RASSF5C in two out of 26 (8%) and RASSF10 in 19 out of 84 (23%) of the cancer samples. No correlation between the methylation status of the analyzed RASSFs or between RASSF methylation and MCC characteristics (primary versus metastatic, Merkel cell polyoma virus infection, age, sex) was found. Our results show that RASSF2, RASSF5C and RASSF10 are aberrantly hypermethylated in MCC to a varying degree and this might contribute to Merkel cell carcinogenesis. PMID:24252868

  5. Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Richter, Antje M.; Haag, Tanja; Walesch, Sara [Institute for Genetics, University of Giessen, Giessen D-35392 (Germany); Herrmann-Trost, Peter [Institute of Pathology, Halle D-06097 (Germany); Marsch, Wolfgang C. [Department of Dermatology, University of Halle, Halle D-06120 (Germany); Kutzner, Heinz [DermPath, Friedrichshafen D-88048 (Germany); Helmbold, Peter [Department of Dermatology, University of Heidelberg, Heidelberg D-69120 (Germany); Dammann, Reinhard H., E-mail: Reinhard.Dammann@gen.bio.uni-giessen.de [Institute for Genetics, University of Giessen, Giessen D-35392 (Germany)

    2013-11-18

    Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. RASSFs are a family of tumor suppressors that are frequently inactivated by promoter hypermethylation in various cancers. We studied CpG island promoter hypermethylation in MCC of RASSF2, RASSF5A, RASSF5C and RASSF10 by combined bisulfite restriction analysis (COBRA) in MCC samples and control tissue. We found RASSF2 to be methylated in three out of 43 (7%), RASSF5A in 17 out of 39 (44%, but also 43% in normal tissue), RASSF5C in two out of 26 (8%) and RASSF10 in 19 out of 84 (23%) of the cancer samples. No correlation between the methylation status of the analyzed RASSFs or between RASSF methylation and MCC characteristics (primary versus metastatic, Merkel cell polyoma virus infection, age, sex) was found. Our results show that RASSF2, RASSF5C and RASSF10 are aberrantly hypermethylated in MCC to a varying degree and this might contribute to Merkel cell carcinogenesis.

  6. Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

    International Nuclear Information System (INIS)

    Richter, Antje M.; Haag, Tanja; Walesch, Sara; Herrmann-Trost, Peter; Marsch, Wolfgang C.; Kutzner, Heinz; Helmbold, Peter; Dammann, Reinhard H.

    2013-01-01

    Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. RASSFs are a family of tumor suppressors that are frequently inactivated by promoter hypermethylation in various cancers. We studied CpG island promoter hypermethylation in MCC of RASSF2, RASSF5A, RASSF5C and RASSF10 by combined bisulfite restriction analysis (COBRA) in MCC samples and control tissue. We found RASSF2 to be methylated in three out of 43 (7%), RASSF5A in 17 out of 39 (44%, but also 43% in normal tissue), RASSF5C in two out of 26 (8%) and RASSF10 in 19 out of 84 (23%) of the cancer samples. No correlation between the methylation status of the analyzed RASSFs or between RASSF methylation and MCC characteristics (primary versus metastatic, Merkel cell polyoma virus infection, age, sex) was found. Our results show that RASSF2, RASSF5C and RASSF10 are aberrantly hypermethylated in MCC to a varying degree and this might contribute to Merkel cell carcinogenesis

  7. Udspring og fald i Alison Bechdels grafiske erindringsværk: "Fun Home. A Family Tragicomic"

    DEFF Research Database (Denmark)

    Gammelgaard, Lasse

    2012-01-01

    Alison Bechdel’s Fun Home. A Family Tragicomic is a graphic memoir about the author’s own coming-out story and her father’s homosexuality and (probable) suicide. It endeavors to give an accurate account of the past, but the telling is simultaneously replete with fictionalising elements. This paper...

  8. Promoting resilience among parents and caregivers of children with cancer.

    Science.gov (United States)

    Rosenberg, Abby R; Baker, K Scott; Syrjala, Karen L; Back, Anthony L; Wolfe, Joanne

    2013-06-01

    Promoting resilience is an aspect of psychosocial care that affects patient and whole-family well-being. There is little consensus about how to define or promote resilience during and after pediatric cancer. The aims of this study were (1) to review the resilience literature in pediatric cancer settings; (2) to qualitatively ascertain caregiver-reported perceptions of resilience; and (3) to develop an integrative model of fixed and mutable factors of resilience among family members of children with cancer, with the goal of enabling better study and promotion of resilience among pediatric cancer families. The study entailed qualitative analysis of small group interviews with eighteen bereaved parents and family members of children with cancer treated at Seattle Children's Hospital. Small-group interviews were conducted with members of each bereaved family. Participant statements were coded for thematic analysis. An integrative, comprehensive framework was then developed. Caregivers' personal appraisals of the cancer experience and their child's legacy shape their definitions of resilience. Described factors of resilience include baseline characteristics (i.e., inherent traits, prior expectations of cancer), processes that evolve over time (i.e., coping strategies, social support, provider interactions), and psychosocial outcomes (i.e., post-traumatic growth and lack of psychological distress). These elements were used to develop a testable model of resilience among family members of children with cancer. Resilience is a complex construct that may be modifiable. Once validated, the proposed framework will not only serve as a model for clinicians, but may also facilitate the development of interventions aimed at promoting resilience in family members of children with cancer.

  9. 77 FR 15605 - Mobile Commerce and Personalization Promotion

    Science.gov (United States)

    2012-03-16

    ... POSTAL SERVICE 39 CFR Part 111 Mobile Commerce and Personalization Promotion AGENCY: Postal... reduction for the mobile commerce and personalization promotion, and the revised mailing standards to... * * * * * [Revise the title of 3.0 as follows:] 3.0 Mobile Commerce and Personalization Promotion 3.1 Program...

  10. [Discussion of the Roles of Medical Social Workers in the Response to the Explosion Incident at Formosa Fun Coast].

    Science.gov (United States)

    Yueh, Hsin-Tien; Sung, Hsien-Yi; Wu, Chia-Feng

    2016-02-01

    Medical social workers apply the theories of "person in the environment" (PIE) and "ecological perspective" as practical foundations. Furthermore, they emphasize the people, the environment, and the interactions between these two. When burn patients from the explosion at Formosa Fun Coast were sent to hospitals, social workers not only provided care and assessed the impact on burn patients but also assisted in supporting the family members of these patients. This article discusses the various roles of social workers within different systems. In the individual system, we use Eric Erickson's theory of psychosocial development to evaluate the patient's crisis and the tasks of social workers. Secondly, in the systems of family, school, and work, we assess the relationships between a patient, his/her significant others, and caregivers as well as the interactions among sub-systems in the family. In the community and cultural systems, we focus on the social resources that may be utilized by the burn patients after discharge. Moreover, we add a time frame to examine our major tasks, including the initial stage, the middle stage, and the preparation-for-discharge stage. We explore the roles of social workers, the applicable theories, and the goals for each stage.

  11. A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites

    DEFF Research Database (Denmark)

    Rose, Christian S; Ek, Jakob; Urhammer, Søren A

    2005-01-01

    of whites, as well as with features of the World Health Organization (WHO)-defined metabolic syndrome. The GCK -30G>A polymorphism was genotyped in the population-based Inter99 study cohort (5,965 subjects) and in 332 nondiabetic subjects and 1,063 patients with type 2 diabetes. In the Inter99 cohort......A graded relationship has been reported between fasting and postprandial plasma glucose levels and the subsequent risk of cardiovascular morbidity and mortality. We hypothesized that the GCK -30G>A promoter polymorphism is associated with elevated glycemia in the middle-aged general population......, the GCK -30A allele was associated with increased fasting (P 1,325 subjects with the metabolic syndrome than among 1,679 subjects without any components...

  12. After 65 years, research is still fun.

    Science.gov (United States)

    Hansel, William

    2013-01-01

    In 1946, at the end of World War II, I entered graduate school at Cornell University, where I remained for 44 years. During that time, my laboratory produced more than 300 publications in the field of reproductive biology, including studies on nutrition and reproduction, the role of the hypothalamus in pituitary gonadotropin release, corpus luteum formation and function, hormone assays, and estrous cycle synchronization. At age seventy, I retired from Cornell and accepted the Gordon Cain Endowed Professorship at Louisiana State University, where I continued my work on the bovine corpus luteum and added research on the collection, maturation, in vitro fertilization, and culture of bovine oocytes. In 1994, I moved to the Pennington Biomedical Research Center and soon thereafter started the research that led to development of the lytic peptide-gonadotropin conjugates, which target and destroy cancer cell membranes. I am continuing my work on the development of targeted cancer cell drugs and, yes, research is still fun!

  13. Offers for our members

    CERN Multimedia

    Staff Association

    2013-01-01

    Summer is here, enjoy our offers for the aquatic parcs! Walibi : Tickets "Zone terrestre": 21 € instead of 26 €. Access to Aqualibi: 5 € instead of 8 € on presentation of your SA member ticket. Free for children (3-11 years old) before 12 h 00. Free for children under 3, with limited access to the attractions. Car park free. * * * * * Aquaparc : Day ticket: – Children: 30 CHF instead of 39 CHF – Adults : 36 CHF instead of 49 CHF Bonus! Free for children under 5.

  14. FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications.

    Science.gov (United States)

    Backenroth, Daniel; He, Zihuai; Kiryluk, Krzysztof; Boeva, Valentina; Pethukova, Lynn; Khurana, Ekta; Christiano, Angela; Buxbaum, Joseph D; Ionita-Laza, Iuliana

    2018-05-03

    We describe a method based on a latent Dirichlet allocation model for predicting functional effects of noncoding genetic variants in a cell-type- and/or tissue-specific way (FUN-LDA). Using this unsupervised approach, we predict tissue-specific functional effects for every position in the human genome in 127 different tissues and cell types. We demonstrate the usefulness of our predictions by using several validation experiments. Using eQTL data from several sources, including the GTEx project, Geuvadis project, and TwinsUK cohort, we show that eQTLs in specific tissues tend to be most enriched among the predicted functional variants in relevant tissues in Roadmap. We further show how these integrated functional scores can be used for (1) deriving the most likely cell or tissue type causally implicated for a complex trait by using summary statistics from genome-wide association studies and (2) estimating a tissue-based correlation matrix of various complex traits. We found large enrichment of heritability in functional components of relevant tissues for various complex traits, and FUN-LDA yielded higher enrichment estimates than existing methods. Finally, using experimentally validated functional variants from the literature and variants possibly implicated in disease by previous studies, we rigorously compare FUN-LDA with state-of-the-art functional annotation methods and show that FUN-LDA has better prediction accuracy and higher resolution than these methods. In particular, our results suggest that tissue- and cell-type-specific functional prediction methods tend to have substantially better prediction accuracy than organism-level prediction methods. Scores for each position in the human genome and for each ENCODE and Roadmap tissue are available online (see Web Resources). Copyright © 2018 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  15. Disentangling fun and enjoyment in exergames using an expanded design, play, experience framework: A narrative review

    Science.gov (United States)

    With exergames (as with physical activity in general), more intense and longer-duration game play should accrue more health benefits. Exergames, however, appear to be played for relatively short durations, often at medium or lower intensities. Ostensibly games are played for fun or enjoyment. Enhanc...

  16. Educational needs of faculty members of Shahid Sadoughi University of Medical Sciences in 2011

    Directory of Open Access Journals (Sweden)

    S. S Mazloomy Mahmoodabad

    2012-11-01

    Full Text Available Introduction: Identifying educational needs is an essential step in planning faculty development programs. It plays an important role in promoting the quality of education. The aim of this study was to determine and prioritize the educational needs of clinical and non clinical faculty members of Faculty of Medicne of Shahid Sadoughi University of Medical Sciences. Methods: A questionnaire was developed for this cross-sectional study using the indices identified by reviewing the literature. The questionnaire was sent to all faculty members of Medical Faculty (n=260. The items were scored from 1 to 20 according to the importance of the educational needs. Data was analyzed by SPSS software. Results: Different areas of educational needs of the clinical faculty members were respectively prioritized as: familiarity with National Medical Universities Ranking Schemeresearch, personal development, administrative and executive activities, education, specialized activities outside the university and health services and health promotion. In the non clinical faculty members: research, familiarity with National Medical Universities Ranking Schemeeducation, personal development, specialized activities outside the university, administrative and executive activities. The first priority of education in the clinical faculty members was design, implementation and analysis of oral exams. In research domain priorities were data analysis skills and the first priority of education in the non clinical faculty members was how to foster critical thinking and reasoning in research and critical appraisal skills. Conclusion: Faculty members need all of the seven studiedmajor areas. It is recommended further research to determine the weight of these seven areas using a standard method.

  17. A função auditoria de sistemas de informação : modelo funcional e de competências

    OpenAIRE

    Silva, Pedro Manuel Gomes da

    2008-01-01

    Dissertação de Mestrado em Tecnologias e Sistemas de Informação - Área de Especialização em Gestão de Sistemas de Informação. O título deste trabalho “A Função Auditoria de Sistemas de Informação: Modelo Funcional e de Competências” reflecte o seu principal objectivo que é propor um modelo com os vários processos de gestão da função Auditoria de SI e com as competências que complementarmente são exigíveis ao Auditor de SI. Este modelo poderá constituir as bases para a elaboraçã...

  18. Application of the FUN3D Unstructured-Grid Navier-Stokes Solver to the 4th AIAA Drag Prediction Workshop Cases

    Science.gov (United States)

    Lee-Rausch, Elizabeth M.; Hammond, Dana P.; Nielsen, Eric J.; Pirzadeh, S. Z.; Rumsey, Christopher L.

    2010-01-01

    FUN3D Navier-Stokes solutions were computed for the 4th AIAA Drag Prediction Workshop grid convergence study, downwash study, and Reynolds number study on a set of node-based mixed-element grids. All of the baseline tetrahedral grids were generated with the VGRID (developmental) advancing-layer and advancing-front grid generation software package following the gridding guidelines developed for the workshop. With maximum grid sizes exceeding 100 million nodes, the grid convergence study was particularly challenging for the node-based unstructured grid generators and flow solvers. At the time of the workshop, the super-fine grid with 105 million nodes and 600 million elements was the largest grid known to have been generated using VGRID. FUN3D Version 11.0 has a completely new pre- and post-processing paradigm that has been incorporated directly into the solver and functions entirely in a parallel, distributed memory environment. This feature allowed for practical pre-processing and solution times on the largest unstructured-grid size requested for the workshop. For the constant-lift grid convergence case, the convergence of total drag is approximately second-order on the finest three grids. The variation in total drag between the finest two grids is only 2 counts. At the finest grid levels, only small variations in wing and tail pressure distributions are seen with grid refinement. Similarly, a small wing side-of-body separation also shows little variation at the finest grid levels. Overall, the FUN3D results compare well with the structured-grid code CFL3D. The FUN3D downwash study and Reynolds number study results compare well with the range of results shown in the workshop presentations.

  19. Job satisfaction and its influential factors in dental academic members in tehran, iran.

    Science.gov (United States)

    Seraj, B; Ghadimi, S; Mirzaee, M; Ahmadi, R; Bashizadeh, H; Ashofteh-Yazdi, K; Sahebjamee, M; Kharazi, Mj; Jahanmehr, M

    2014-03-01

    Assessment of job satisfaction of the faculty members and its underlying factors may increase career fulfillment and raise the educational and research productivity, leading to higher quality of dental services at the community level, ultimately improving public oral health status. This study assessed job satisfaction and its influential factors in dental academic members in Tehran. The job satisfaction level of 203 faculty members was assessed using a Likert scale questionnaire from 0 to 4, with 4 representing very satisfied and 0 not at all satisfied. The analysis of variance was used to compare the responses among dental faculty members of three different universities. The impact of age, gender, academic rank, employment status and the date of employment on the overall faculty job satisfaction was identified by multiple linear regression analysis. The mean professional satisfaction score among faculty members was 1.5 (0.5) out of four. Among the studied underlying factors, only the date of employment was seen to have a statistically significant impact on the faculties' overall job satisfaction (P= 0.05). There was no difference in job compensation observed between the three dental faculties. Dissatisfying aspects of the academic work included educational and research policies, monetary strategies, quality of leadership and administration, promotion and tenure policies, job security, educational environment, equipments, and facilities. The only satisfying factor was the interaction between faculty colleagues and students. Faculty members of Tehran Dental Schools are dissatisfied with their work environments in Tehran Dental Schools. Issues such as salary and remuneration, facilities, equipments, promotion and tenure policies are strongly believed to account for the dissatisfaction.

  20. The Influence Of Brand Positioning Fun, Art And Education Bale Seni Barli-Kota Baru Parahyangan Toward Visit Decision In Bale Seni Barli-Kota Baru Parahyangan

    Directory of Open Access Journals (Sweden)

    Vany Octaviany

    2015-10-01

    Full Text Available Bale Seni Barli-Kota Baru Parahyangan is one tourist attraction (DTW art which is located in Kota Baru Parahyangan, Padalarang. Number of tourists visiting Bale Seni Barli-Kota Baru Parahyangan from year to year has increased, but did not meet the expected targets visit the manager. Building a strong Brand Positioning able to provide a reference for tourists in choosing DTW to be addressed which can then influence the decision of tourists to visit a DTW. Therefore Bale Seni Barli-Kota Baru Parahyangan trying to build a strategy Brand Positioning Fun, Art and Education in order to position itself as DTW which offers attractions and tourist activity-laden art education but still fun for tourists. This study aims to find out about how much influence the Brand Positioning Fun, Art and Education against the decision of visiting tourists in Bale Seni Barli-Kota Baru Parahyangan. In this study, the independent variable (X is the Brand Positioning and the dependent variable was the decision to visit, with a sample of 100 respondents, data collection techniques using a questionnaire (questionnaire, interviews, documentary studies and literature studies, while data analysis techniques using simple regression. The results showed that the influence strategy Brand Positioning Fun, Art and Education on the decision been run Bale Seni Barli-Kota Baru Parahyangan have a strong influence, which amounted to 83%. This shows that when Brand Positioning Fun, Art and Education implemented properly, then the decision to tourists visiting Bale Seni Barli-Kota Baru Parahyangan will increase.

  1. Electronic game: A key effective technology to promote behavioral change in cancer patients

    Directory of Open Access Journals (Sweden)

    Reza Safdari

    2016-01-01

    Full Text Available Cancer diagnosis is a very unpleasant and unbelievable experience. Appropriate management and treatment of these diseases require a high degree of patient engagement. Interactive health electronic games are engaging, fun, challenging, and experiential and have the potential to change the attitude and behavior, which can improve the player's health. The use of these digital tools, as one of the most attractive and entertaining modern technologies, canem power patients, provide suitable palliative care, promote health behavior change strategies, increase patient engagement, enhance healthy lifestyle habits, improve self.management, and finally improve the quality of life of the patients. Finally, the aim of this article was to describe electronic games and their effects on the promotion of behavior change in cancer patients. In addition, this article describes categories, characteristic features, and benefits of this digital media in the lifestyle modification of cancer patients.

  2. Breaking with fun, educational and realistic learning games

    DEFF Research Database (Denmark)

    Duus Henriksen, Thomas

    2009-01-01

    are commonly conceived as means for staging learning processes, and that thinking learning games so has an inhibiting effect in regard to creating learning processes. The paper draws upon a qualitative study of participants' experiences with ‘the EIS Simulation', which is a computer-based learning game......This paper addresses the game conceptions and values that learning games inherit from regular gaming, as well as how they affect the use and development of learning games. Its key points concern the issues of thinking learning games as fun, educative and realistic, which is how learning games...... for teaching change management and change implementation. The EIS is played in groups, who share the game on a computer, and played by making change decisions in order to implement an IT system in an organisation. In this study, alternative participatory incentives, means for creating learning processes...

  3. [Outcomes evaluation of the school staff health promotion project].

    Science.gov (United States)

    Woynarowska-Sołdan, Magdalena

    This article presents selected outcomes of a 3-year project "Health promotion of school staff in health-promoting schools," as well as the achievements and difficulties in its implementation. The research was conducted on 644 teachers and 226 members of non-teaching staff in 21 schools. The method involved opinion poll and authored questionnaires. A 2-part model of outcome evaluation was developed. Most participants appreciated the changes that took place within the 3 years of the project implementation. These included the improved level of their knowledge about health, health-conducive behaviors (62-93%) and the physical and social environment of the school (50-92%). Changes were more frequently acknowledged by teachers. About 80% of the participants had a positive attitude to the project, but only 20% assessed their involvement as considerable. About 90% believed that health promotion activities should be continued. According to the project leaders, insufficient support and financial resources, and difficulties in motivating school employees, particularly the nonteaching staff, to undertake health-promotion activities were the major handicaps in the project implementation. The project outcomes can be assessed as satisfying. They revealed that it is posssible to initiate health promotion among school staff. This can be effective on condition that participants are motivated, actively engaged in the project and supported by the head teacher and the local community. Necessarily, school leaders should be prepared to promote health among adults and to gain support from school policy decision makers, school administration, trade unions and universities involved in teacher training. Med Pr 2016;67(2):187-200. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  4. Job Satisfaction in Basic and Clinical Faculty Members in Shiraz University of Medical Sciences, Iran

    Directory of Open Access Journals (Sweden)

    Mehdi Saberi-Firoozi

    2009-02-01

    Full Text Available Background and Purpose: Shiraz University of Medical Sciences as one of the oldest and largest universities of medicine in Iran with 50 years history has more than 450 faculty members and 5000 students. This study is an attempt to find out the level of job satisfaction among Shiraz University ofMedical Sciences’ faculty members.Methods: In midterm of 2003-2004, data on job satisfaction level among 404 faculty members from all schools of Shiraz University of Medical Sciences were collected. The translation of Spector’s job satisfaction score was used including 34 questions in 9 items of job satisfaction and each one based on Likert’s Scale with score an of 1-5. A question related to overall job satisfaction of faculty members was added.Results: Of all faculties,, 252 responded to the questionnaire and 70.1% expressed satisfaction in response the added question. The mean scores of job satisfaction in items of coworkers, work nature, supervision, management methods, academic relations, promotion, salary and suitable benefits were3.771, 3.265, 2.557, 2.454, 2.395, and 2.376 out of 5 respectively (F=223.8, p=0.0001. In the promotion item, the satisfaction of female faculty was lower than male subjects. The level of job satisfaction was not different between clinical faculty members of Medical School with or without private activity. The results of linear regression analysis between the items of job satisfaction revealed that reimbursement and fringe benefits could predict the overall job satisfaction (r2=0.70, p<0.01.Conclusion: As a whole, the faculty members of the university were satisfied with their jobs, but a correction in reimbursement, benefits and promotion regulations especially in lower academic ranks is needed to improve the level of job satisfaction in this group.Key words: JOB SATISFACTION, FACULTY MEMBER, BASIC AND CLINICAL DEPARTMENTS, FULLTIME, PART-TIME

  5. Developing a coding scheme for detecting usability and fun problems in computer games for young children

    NARCIS (Netherlands)

    Barendregt, W.; Bekker, M.M.

    2006-01-01

    This article describes the development and assessment of a coding scheme for finding both usability and fun problems through observations of young children playing computer games during user tests. The proposed coding scheme is based on an existing list of breakdown indication types of the detailed

  6. Memória Auditiva-Verbal e Funções Executivas em Crianças Bilingues (Português Europeu/Francês) e Monolingues (Português Europeu) dos 10 aos 11 anos de idade

    OpenAIRE

    Spínola, Jennifer Gomes

    2011-01-01

    O principal objectivo deste estudo foi verificar se o desempenho de crianças bilingues difere das monolingues no que concerne à memória auditiva-verbal e funções executivas. Neste estudo de carácter descritivo-comparativo participaram 70 estudantes do 5º ano de escolaridade, com idades compreendidas entre os 10 e 11 anos de idade. (M= 10,24; DP= 0,43). Dos 70 estudantes, 30 são bilingues (Português Europeu/ Francês) e frequentam o ensino bilingue e 40 são monolingues (Português Europeu) e fre...

  7. Código Florestal, função socioambiental da terra e soberania alimentar

    Directory of Open Access Journals (Sweden)

    Sérgio Sauer

    Full Text Available O presente artigo tem como objetivo discutir alterações do Código Florestal, especialmente aspropostas de mudanças nas noções de Reserva Legal e Área de Preservação Permanente (APP, em processo de rediscussão no Congresso, após sanção presidencial com vetos no texto aprovado na Câmara em 25 de abril de 2012. Para suprir lacunas da nova Lei, o Executivo Federal editou a Medida Provisória (MP 571/2012, que retoma a discussão da matéria. Tanto dispositivos da nova Lei como alterações propostas ao texto da MP geram insegurança alimentar e visam a eliminar a função socioambiental da terra. A motivação das mudanças não está relacionada à sustentabilidade ambiental ou às mudanças climáticas, temas fundamentais na agenda mundial, mas parte do princípio de que a natureza é um empecilho ao desenvolvimento. Este artigo resgata as principais alterações no Código Florestal relacionadas à Reserva Legal e às APPs, estabelecendo relações (impactos negativos com a função socioambiental da terra e a soberania alimentar.

  8. A systematic review of persuasive marketing techniques to promote food to children on television.

    Science.gov (United States)

    Jenkin, G; Madhvani, N; Signal, L; Bowers, S

    2014-04-01

    The ubiquitous marketing of energy-dense, nutrient-poor food and beverages is a key modifiable influence on childhood dietary patterns and obesity. Much of the research on television food advertising is focused on identifying and quantifying unhealthy food marketing with comparatively few studies examining persuasive marketing techniques to promote unhealthy food to children. This review identifies the most frequently documented persuasive marketing techniques to promote food to children via television. A systematic search of eight online databases using key search terms identified 267 unique articles. Thirty-eight articles met the inclusion criteria. A narrative synthesis of the reviewed studies revealed the most commonly reported persuasive techniques used on television to promote food to children. These were the use of premium offers, promotional characters, nutrition and health-related claims, the theme of taste, and the emotional appeal of fun. Identifying and documenting these commonly reported persuasive marketing techniques to promote food to children on television is critical for the monitoring and evaluation of advertising codes and industry pledges and the development of further regulation in this area. This has a strong potential to curbing the international obesity epidemic besieging children throughout the world. © 2014 The Authors. obesity reviews © 2014 International Association for the Study of Obesity.

  9. 100 commonly asked questions in math class answers that promote mathematical understanding, grades 6-12

    CERN Document Server

    Posamentier, Alfred S (Steven); Germain-Williams, Terri L (Lynn); Paris, Elaine S; Lehmann, Ingmar H (Horst)

    2013-01-01

    100 ways to get students hooked on math! That one question got you stumped? Or maybe you have the answer, but it's not all that compelling. Al Posamentier and his coauthors to the rescue with this handy reference containing fun answers to students'100 most frequently asked math questions. Even if you already have the answers, Al's explanations are certain to keep kids hooked. The big benefits? You'll discover high-interest ways to Teach to the Common Core's math content standards Promote inquiry and process in mathematical thinking Build procedural skills and conceptual understanding Encourage

  10. Offers for our members

    CERN Multimedia

    Association du personnel

    2013-01-01

    La banque LCL propose aux membres de l’Association du personnel les avantages suivants : – Un barème Privilège sur le Prêt immobilier – Des avantages tarifaires sur l’épargne, notamment l’assurance-vie. – Un taux préférentiel de prêt à la consommation. En outre, jusqu’au 30 septembre 2013, elle offre 50€ à tous les nouveaux clients, membres de l'Association du personnel. Summer is here, enjoy our offers for the aquatic parcs! Tickets "Zone terrestre" : 21 € instead of de 26 €. Access to Aqualibi : 5 euros instead of 8 euros on presentation of your SA member ticket. Free for children (3-11 years old) before 12 h 00. Free for children under 3, with limited access to the attractions. Free car park. * * * * * * * Full day ticket: – Children : 30 CHF instead of 39 CHF &...

  11. Promotion through Marketing Channels : The Case of Kosovo

    OpenAIRE

    MSc. Hidajet Karaxha; MSc. Sejd Tolaj; Dr.Sc. Ilia Kristo

    2016-01-01

    In order for a product to be put in the hands of the customer, requires a mechanism which is called distribution channel and which enables the connection between the consumer and producer. One of the many strategies applied by Kosovar companies for the involvement of the members of the channel is also the promotion through distribution channels. Therefore, the strategies which involve the members of the channel have a higher probability to be positively accepted by the members of the channel,...

  12. Netball team members, but not hobby group members, distinguish team characteristics from group characteristics.

    Science.gov (United States)

    Stillman, Jennifer A; Fletcher, Richard B; Carr, Stuart C

    2007-04-01

    Research on groups is often applied to sport teams, and research on teams is often applied to groups. This study investigates the extent to which individuals have distinct schemas for groups and teams. A list of team and group characteristics was generated from 250 individuals, for use in this and related research. Questions about teams versus groups carry an a priori implication that differences exist; therefore, list items were presented to new participants and were analyzed using signal detection theory, which can accommodate a finding of no detectable difference between a nominated category and similar items. Participants were 30 members from each of the following: netball teams, the general public, and hobby groups. Analysis revealed few features that set groups apart from teams; however, teams were perceived as more structured and demanding, requiring commitment and effort toward shared goals. Team and group characteristics were more clearly defined to team members than they were to other participant groups. The research has implications for coaches and practitioners.

  13. Efeitos de diferentes graus de sensibilidade a insulina na função endotelial de pacientes obesos

    Directory of Open Access Journals (Sweden)

    Roberto Galvão

    2012-01-01

    Full Text Available FUNDAMENTO: A obesidade derivada da deposição de gordura intra-abdominal tende a aumentar a produção de hormônios e citoquinas, piorando a sensibilidade a insulina e levando a disfunção endotelial. A hiperinsulinemia é considerada um fator de risco independente para doença isquêmica cardíaca e é uma causa de disfunção endotelial em indivíduos saudáveis. OBJETIVO: Avaliar o impacto de diferentes graus de resistência a insulina, medida pelo HOMA-IR (Homeostasis Model Assessment of Insulin Resistance, sobre a função endotelial de obesos, pacientes não diabéticos, sem história prévia de eventos cardiovasculares e diversos componentes da síndrome metabólica. MÉTODOS: Um total de 40 indivíduos obesos foi submetido a medidas antropométricas, pressão arterial de consultório, MAPA e exames laboratoriais, além de avaliação ultrassonográfica não invasiva da função endotelial. Os pacientes foram divididos em três grupos de acordo com o grau de resistência a insulina: pacientes com valores de HOMA-IR entre 0,590 e 1,082 foram incluídos no Grupo 1 (n = 13; entre 1,083 e 1,410 no Grupo 2 (n = 14; e entre 1,610 e 2,510 no Grupo 3 (n = 13. RESULTADOS: Encontramos uma diferença significativa na vasodilatação mediada por fluxo no Grupo 3 em relação ao Grupo 1 (9,2 ± 7,0 vs 18,0 ± 7,5 %, p = 0,006. Houve uma correlação negativa entre a função endotelial e insulina, HOMA-IR e triglicérides. CONCLUSÃO: Nosso estudo sugere que leves alterações nos níveis de resistência a insulina avaliada pelo HOMA-IR podem causar algum impacto sobre a função vasodilatadora do endotélio em indivíduos obesos não complicados com diferentes fatores de risco cardiovascular.

  14. Agreement on the privileges and immunities of the Agency. Status list as of 30 September 2002. Acceptances by Member States. Declarations/reservations made upon expressing consent to be bound and objections thereto

    International Nuclear Information System (INIS)

    2002-01-01

    The document lists the 70 Members which, by 30 September 2002, had accepted the Agreement on the Privileges and Immunities of the International Atomic Energy Agency, as provided for in Section 38 thereof. The list is followed by the texts of declarations/reservations made to the Agreement

  15. Improving Emotion Regulation and Sibling Relationship Quality: The More Fun with Sisters and Brothers Program

    Science.gov (United States)

    Kennedy, Denise E.; Kramer, Laurie

    2008-01-01

    We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…

  16. Use of the vital stain FUN-1 indicates viability of Phytophthora capsici propagules and can be used to predict maximum zoospore production.

    Science.gov (United States)

    Lewis Ivey, Melanie L; Miller, Sally A

    2014-01-01

    The fluorescent vital dye FUN®-1 (2-chloro-4-[2,3-dihydro-3-methyl-{benzo-1,3-thiazol-2-yl}-methylidene]-1-phenylquinolinium iodide) was evaluated as a tool to assess Phytophthora capsici sporangia and zoospore metabolic activity and viability. Under aerobic conditions, mycelia, sporangia and zoospores cultured on agar medium and stained with FUN-1 exhibited red fluorescent cylindrical intravacuolar structures (CIVS) that were clearly visible at 100× magnification. Encysted zoospores did not exhibit CIVS after exposure to FUN-1 dye. Over 7 d there was a significant reduction in the percent of sporangia containing CIVS, which corresponded with a significant increase in zoospore formation and release. The decline in the percentage of metabolically active sporangia and increase in the number of zoospores fit both a linear and log regression model. The FUN-1 dye was suitable for distinguishing between live and dead sporangia and effective in monitoring the change in metabolic activity of sporangia over time. It will be useful in determining parameters, including P. capsici culture age, that maximize production of zoospores in vitro.

  17. Marcadores práticos de função renal em pacientes com cistinose

    Directory of Open Access Journals (Sweden)

    Luciana Pache de Faria Guimaraes

    2012-09-01

    Full Text Available INTRODUÇÃO: Cistinose é uma doença sistêmica, autossômica recessiva, que leva à insuficiência renal crônica na infância, a não ser que o tratamento com cisteamina seja iniciado precocemente. Mesmo nestas condições, os pacientes evoluem para doença renal crônica terminal por volta da segunda década da vida. Portanto, a avaliação da função renal é essencial neste grupo de pacientes. OBJETIVO: Avaliar e correlacionar a cistatina C, creatinina sérica e o clearance de creatinina pela Fórmula de Schwartz em pacientes com cistinose, com diferentes graus de função renal. MÉTODOS: Foram incluídos pacientes com menos de 18 anos de idade, com diferentes níveis de função renal, de acordo com o KDOQI em estágios 1 a 4. Nenhum dos pacientes estava em terapia de substituição renal. Foram medidos os seguintes parâmetros: cistatina C, creatinina sérica e o clearance de creatinina pela fórmula de Schwartz. RESULTADOS: Foram analisadas 103 amostras de sangue de 26 pacientes. Foi detectada correlação significativa entre creatinina sérica e cistatina C (r = 0,81, p < 0,0001, cistatina C e o clearance de creatinina pela fórmula de Schwartz (r = -0,84, p < 0,0001 e creatinina sérica e clearance de creatinina (r = -0,97, p < 0,0001. CONCLUSÕES: A medida da cistatina não mostrou nenhuma vantagem sobre a creatinina sérica e o clearance de creatinina pela fórmula de Schwartz em pacientes com cistinose para avaliar o ritmo de filtração glomerular. Este é o primeiro relato sobre o valor da creatinina sérica, do clearance de creatinina pela fórmula de Schwartz e da cistatina C em pacientes com cistinose.

  18. The status of mycology in Africa: A document to promote awareness.

    Science.gov (United States)

    Gryzenhout, Marieka; Jefwa, Joyce M; Yorou, Nourou S

    2012-06-01

    The African Mycological Association (AMA) promotes mycology amongst members in Africa and globally. The AMA has about 200 members, mostly from African states but also with strong representation from Europe and USA, amongst others. Recent efforts by members of the AMA focused on reviving and developing mycological research and networking in Africa. A great deal must, however, still be done to promote the AMA under African mycologists, and those elsewhere with interests in Africa. African mycologists also experience challenges typical of the developing world and a great deal of fungi still needs to be discovered. This can also be seen as representing great opportunities for research and collaboration. Several issues pertinent to mycology in Africa were discussed during Special Interest Group sessions of the 9th International Mycological Congress in 2010, and through several opinion pieces contributed by AMA members in the AMA newsletter, MycoAfrica. This contribution serves as a document to summarise these in a form that can be presented to fellow mycologists, biologists and other scientists, relevant government departments, funding bodies and Non-Governmental Organizations and that pins down the importance of mycology, the status thereof in Africa and the need to promote it more.

  19. Stimulation of the growth of Jatropha curcas by the plant growth promoting bacterium Enterobacter cancerogenus MSA2.

    Science.gov (United States)

    Jha, Chaitanya Kumar; Patel, Baldev; Saraf, Meenu

    2012-03-01

    A novel Enterobacter cancerogenus MSA2 is a plant growth promoting gamma-proteobacterium that was isolated from the rhizosphere of Jatropha cucas a potentially important biofuel feed stock plant. Based on phenotypic, physiological, biochemical and phylogenetic studies, strain MSA2 could be classified as a member of E. cancerogenus. However, comparisons of characteristics with other known species of the genus Enterobacter suggested that strain MSA2 could be a novel PGPB strain. In vitro studies were carried for the plant growth promoting attribute of this culture. It tested positive for ACC (1-aminocyclopropane-1-carboxylic acid) deaminase production, phytase, phosphate solubilization, IAA (Indole acetic acid) production, siderophore, and ammonia production. The isolate was then used as a inoculant for the vegetative study of Jatropha curcas plant. Enterobacter cancerogenus MSA2 supplemented with 1% carboxymethylcellulose showed overall plant growth promotion effect resulting in enhanced root length (124.14%), fresh root mass (81%), fresh shoot mass (120.02%), dry root mass (124%), dry shoot mass (105.54%), number of leaf (30.72%), chlorophyll content (50.41%), and biomass (87.20%) over control under the days of experimental observation. This study was designed for 120 days and was in triplicate and the data was collected at every 30 days.

  20. Elections of members to the Governing Board of the Pensions Fund

    CERN Multimedia

    2005-01-01

    This year, two members and two alternates are to be elected. The candidates who obtain most votes will be elected members and the other candidates will be their alternates. New timetable (extract) : Monday 10 January 2005 Second publication of the candidates' publicity and the statement from all the candidates in the Bulletin. Monday 31 January 2005 Voting closes at 12 hrs. Counting of votes from 14.30 hrs. Tuesday 1st February 2005 Forwarding of results to the Communications Section for publication in the Bulletin of 7 February. Statement from the Candidates for Election to the Governing Board of the Pension Fund The composition of the Governing Board of the CERN Pension Fund is as follows. two members appointed by the CERN council and two alternates two members appointed by the DG of CERN and two alternates one member appointed by the Staff Association and one alternate one member appointed by the DG of ESO and one alternate four members elected by the members of the fund and four ...

  1. Les inscriptions funéraires au cimetière d’Aïn El-Beida (Oran) : état des lieux

    OpenAIRE

    Hirreche Baghdad, Mohamed

    2016-01-01

    Ce papier résulte d’un projet établissement inscrit au CRASC (2009-2013) intitulé : « les inscriptions sur les stèles funéraires dans l’ouest algérien : permanence et évolution ». La problématique de ce projet est la suivante : qu’écrivent les algériens sur les tombes de leurs proches et comment expliquer la divergence ou la ressemblance des contenus épigraphiques des stèles funéraires ? La première partie de la question s’intéresse à l’état des lieux de l’épigraphie au cimetière d’Aïn El-Bei...

  2. Celulares, Funções pós-midiáticas, Cidade e Mobilidade Mobile phones, postmediatic functions, city and mobility

    OpenAIRE

    André Lemos

    2010-01-01

    O objetivo desse artigo é compreender a relação entre as novas tecnologias de comunicação e informação(TICs) e o espaço urbano a partir de uma discussão sobre a mobilidade. Para tanto, o artigo propõe alguns princípios para a compreensão desse fenômeno: 1) a nova configuração comunicacional, que chamo de funções pós-massivas em contraposição à ideia de mídias de massa; 2) as novas funções e heterotopias dos lugares com a emergência de territórios informacionais, compreendendo aqui comoas nova...

  3. Using Fun in the Statistics Classroom: An Exploratory Study of College Instructors' Hesitations and Motivations

    Science.gov (United States)

    Lesser, Lawrence M.; Wall, Amitra A.; Carver, Robert H.; Pearl, Dennis K.; Martin, Nadia; Kuiper, Shonda; Posner, Michael A.; Erickson, Patricia; Liao, Shu-Min; Albert, Jim; Weber, John J., III

    2013-01-01

    This study examines statistics instructors' use of fun as well as their motivations, hesitations, and awareness of resources. In 2011, a survey was administered to attendees at a national statistics education conference, and follow-up qualitative interviews were conducted with 16 of those ("N" = 249) surveyed to provide further…

  4. The Effect o f Entertaining Fun Athletics Training Program R elated To the Self - Confidence Levels among Children Aged 12 - 14 Years

    Directory of Open Access Journals (Sweden)

    Erkan YARIMKAYA

    2014-12-01

    Full Text Available The aim of this study is to examine the effect of entertaining fun athletics training program on the self - conf i dence levels of children. The sample group of the study is occuring 160 students in 12 - 14 age group from Keçiören Hacı Sabancı Primary School loc ated in Keçiören district of Ankara. Both the experimental and the control group were applied Piers - Harris Self - Confidence test developed by Piers and Harr i s (1984 before and after 8 - week procedure. The SPSS statistical program (version 15.0 was used for data analysis.The research indicates a statistical difference (P<0,05 between the experimental and the control group in terms of post - test. In the compari son of pre - test and post - test results of the experimental group, there is a significant difference between pre - test and post - test results. ( P<0,05. In those comparisons, it was found that the post - test results are higher than pre - test results. As a resul t, in the survey made for inspecting the self - confidence of the children in 12 – 14 age group who are making e ntertaining fun athletics excersises, it is fixed that the entertaining fun athletics excersise applied to the test group effects the self - confide nce level of the kids significiantly. In this context, we can say that e ntertaining fun athletics excersise positively effect the self - confidence properties of the kids in 12 - 14 age group.

  5. OSART Works to Help Member States

    International Nuclear Information System (INIS)

    Kaiser, Peter

    2013-01-01

    Full text: Nuclear safety is a never ending pursuit for improvement, and one of the more prominent IAEA efforts that help Member States achieve higher levels of safety is the Operational Safety Review Team (OSART) programme. In OSART missions, the IAEA coordinates internationally-based teams of experts who conduct reviews of operational safety performance at nuclear power plants. The IAEA on 14 June 2013 marked the 30th anniversary of OSART. In 1983, the Agency conducted its first OSART mission to the Kori Nuclear Power Plant in the Republic of Korea, and it conducted a total of 174 OSART missions over the following 30 years. The reviews have been done in 34 nations at 103 nuclear sites. (author)

  6. Exercise habit formation in new gym members: a longitudinal study.

    Science.gov (United States)

    Kaushal, Navin; Rhodes, Ryan E

    2015-08-01

    Reasoned action approaches have primarily been applied to understand exercise behaviour for the past three decades, yet emerging findings in unconscious and Dual Process research show that behavior may also be predicted by automatic processes such as habit. The purpose of this study was to: (1) investigate the behavioral requirements for exercise habit formation, (2) how Dual Process approach predicts behaviour, and (3) what predicts habit by testing a model (Lally and Gardner in Health Psychol Rev 7:S137-S158, 2013). Participants (n = 111) were new gym members who completed surveys across 12 weeks. It was found that exercising for at least four bouts per week for 6 weeks was the minimum requirement to establish an exercise habit. Dual Process analysis using Linear Mixed Models (LMM) revealed habit and intention to be parallel predictors of exercise behavior in the trajectory analysis. Finally, the habit antecedent model in LLM showed that consistency (β = .21), low behavioral complexity (β = .19), environment (β = .17) and affective judgments (β = .13) all significantly (p < .05) predicted changes in habit formation over time. Trainers should keep exercises fun and simple for new clients and focus on consistency which could lead to habit formation in nearly 6 weeks.

  7. The use of Goal Attainment Scaling in a community health promotion initiative with seniors.

    Science.gov (United States)

    Kloseck, Marita

    2007-07-03

    Evaluating collaborative community health promotion initiatives presents unique challenges, including engaging community members and other stakeholders in the evaluation process, and measuring the attainment of goals at the collective community level. Goal Attainment Scaling (GAS) is a versatile, under-utilized evaluation tool adaptable to a wide range of situations. GAS actively involves all partners in the evaluation process and has many benefits when used in community health settings. The purpose of this paper is to describe the use of GAS as a potential means of measuring progress and outcomes in community health promotion and community development projects. GAS methodology was used in a local community of seniors (n = 2500; mean age = 76 +/- 8.06 SD; 77% female, 23% male) to a) collaboratively set health promotion and community partnership goals and b) objectively measure the degree of achievement, over- or under-achievement of the established health promotion goals. Goal attainment was measured in a variety of areas including operationalizing a health promotion centre in a local mall, developing a sustainable mechanism for recruiting and training volunteers to operate the health promotion centre, and developing and implementing community health education programs. Goal attainment was evaluated at 3 monthly intervals for one year, then re-evaluated again at year 2. GAS was found to be a feasible and responsive method of measuring community health promotion and community development progress. All project goals were achieved at one year or sooner. The overall GAS score for the total health promotion project increased from 16.02 at baseline (sum of scale scores = -30, average scale score = -2) to 54.53 at one year (sum of scale scores = +4, average scale score = +0.27) showing project goals were achieved above the expected level. With GAS methodology an amalgamated score of 50 represents the achievement of goals at the expected level. GAS provides a

  8. The use of Goal Attainment Scaling in a community health promotion initiative with seniors

    Directory of Open Access Journals (Sweden)

    Kloseck Marita

    2007-07-01

    Full Text Available Abstract Background Evaluating collaborative community health promotion initiatives presents unique challenges, including engaging community members and other stakeholders in the evaluation process, and measuring the attainment of goals at the collective community level. Goal Attainment Scaling (GAS is a versatile, under-utilized evaluation tool adaptable to a wide range of situations. GAS actively involves all partners in the evaluation process and has many benefits when used in community health settings. Methods The purpose of this paper is to describe the use of GAS as a potential means of measuring progress and outcomes in community health promotion and community development projects. GAS methodology was used in a local community of seniors (n = 2500; mean age = 76 ± 8.06 SD; 77% female, 23% male to a collaboratively set health promotion and community partnership goals and b objectively measure the degree of achievement, over- or under-achievement of the established health promotion goals. Goal attainment was measured in a variety of areas including operationalizing a health promotion centre in a local mall, developing a sustainable mechanism for recruiting and training volunteers to operate the health promotion centre, and developing and implementing community health education programs. Goal attainment was evaluated at 3 monthly intervals for one year, then re-evaluated again at year 2. Results GAS was found to be a feasible and responsive method of measuring community health promotion and community development progress. All project goals were achieved at one year or sooner. The overall GAS score for the total health promotion project increased from 16.02 at baseline (sum of scale scores = -30, average scale score = -2 to 54.53 at one year (sum of scale scores = +4, average scale score = +0.27 showing project goals were achieved above the expected level. With GAS methodology an amalgamated score of 50 represents the achievement of goals at

  9. Social support from teachers mediates physical activity behavior change in children participating in the Fit-4-Fun intervention.

    Science.gov (United States)

    Eather, Narelle; Morgan, Philip J; Lubans, David R

    2013-05-28

    Few studies have examined the mediators of behavior change in successful school-based physical activity interventions. The aim of this study was to explore potential mediators of physical activity in the Fit-4-Fun program for primary school children. Group randomized controlled trial. Four primary schools were recruited in April, 2011 and randomized by school into intervention or control conditions. Participants included 213 children (mean age = 10.7 years ± 0.6; 52.2% female) with the treatment group (n = 118) completing the 8-week multi-component Fit-4-Fun program. Participants were assessed at baseline, 3- and 6-months. Physical activity was measured using Yamax SW700 pedometers (mean steps/day) and questionnaires were used to assess constructs from Social Cognitive Theory and Competence Motivation Theory. Hypothesized mediators measured included social support from peers, parents and teachers; physical activity self-efficacy (barrier and task); enjoyment; and perceived school physical environment. Mediation was assessed using Preacher and Hayes' multiple mediation regression SPSS macro. Action theory (A), conceptual theory (B) and the significance of the product of coefficients (AB) are reported. The intervention had a significant effect on physical activity (pFun program successfully targeted social support for physical activity provided by classroom teachers which contributed to improved physical activity in children. These results demonstrate that classroom teachers play a key role in influencing physical activity behavior outcomes in children.Trial Registration No: ACTRN12611000976987.

  10. Does the Animal Fun program improve social-emotional and behavioural outcomes in children aged 4-6 years?

    NARCIS (Netherlands)

    Piek, J.P.; Kane, R.; Rigoli, D.; McLaren, S.; Roberts, C.M.; Rooney, R.; Jensen, L.; Dender, A.; Packer, T.L.; Straker, L.

    2015-01-01

    Animal Fun was designed to enhance motor and social development in young children. Its efficacy in improving motor skills was presented previously using a randomised controlled trial and a multivariate nested cohort design. Based on the Environmental Stress Hypothesis, it was argued that the program

  11. Sometimes more is more: iterative participatory design of infographics for engagement of community members with varying levels of health literacy.

    Science.gov (United States)

    Arcia, Adriana; Suero-Tejeda, Niurka; Bales, Michael E; Merrill, Jacqueline A; Yoon, Sunmoo; Woollen, Janet; Bakken, Suzanne

    2016-01-01

    To collaborate with community members to develop tailored infographics that support comprehension of health information, engage the viewer, and may have the potential to motivate health-promoting behaviors. The authors conducted participatory design sessions with community members, who were purposively sampled and grouped by preferred language (English, Spanish), age group (18-30, 31-60, >60 years), and level of health literacy (adequate, marginal, inadequate). Research staff elicited perceived meaning of each infographic, preferences between infographics, suggestions for improvement, and whether or not the infographics would motivate health-promoting behavior. Analysis and infographic refinement were iterative and concurrent with data collection. Successful designs were information-rich, supported comparison, provided context, and/or employed familiar color and symbolic analogies. Infographics that employed repeated icons to represent multiple instances of a more general class of things (e.g., apple icons to represent fruit servings) were interpreted in a rigidly literal fashion and thus were unsuitable for this community. Preliminary findings suggest that infographics may motivate health-promoting behaviors. Infographics should be information-rich, contextualize the information for the viewer, and yield an accurate meaning even if interpreted literally. Carefully designed infographics can be useful tools to support comprehension and thus help patients engage with their own health data. Infographics may contribute to patients' ability to participate in the Learning Health System through participation in the development of a robust data utility, use of clinical communication tools for health self-management, and involvement in building knowledge through patient-reported outcomes. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Health promotion and young prisoners: a European perspective.

    Science.gov (United States)

    MacDonald, Morag; Rabiee, Fatemeh; Weilandt, Caren

    2013-01-01

    The purpose of this paper is to assess the health promotion needs of vulnerable young prisoners and the existing health promotion activities in custodial settings in seven European Union (EU) Member States. The research comprised two components: the first involved identifying existing health promotion practices. The second involved mapping out young offenders' health promotion needs by carrying out a needs assessment. Both quantitative and qualitative methods were adopted. The quantitative element comprised surveys among young prisoners and prison staff and focused on the availability and perceived importance of health promotion activities in prison. The qualitative element comprised focus groups with young offenders and individual interviews with prison staff, field experts and NGO members. The findings from the research have identified a number of similar, but also some diverse areas of unmet need for health promotion activities in prison settings across these diverse seven EU countries. There is no consistency of approach within and between countries regarding health promotion policy, guidance, resources and programmes for young prisoners. In order to improve the health of young prisoners and to establish and increase sustainability of existing health promotion programmes, there is a need for the establishment of National and EU standards. Providing health promotion activities for young prisoners while in custodial settings is key to addressing their unmet health and well-being needs and to facilitate their reintegration back into the community. Despite the barriers identified by this research, health promotion is to some extent being delivered in the partner countries and provides a foundation upon which further implementation of health promotion activities can be built especially when the benefits of health promotion activities, like dealing with the common problems of alcohol and drug addiction, mental health and communicable diseases are linked to successful

  13. Leading by Example: Health Promotion Programs for School Staff

    Science.gov (United States)

    Herbert, Patrick C.; Lohrmann, David K.

    2011-01-01

    Health promotion programs for school staff are an overlooked and underused resource that can reduce overweight and obesity among teachers and other staff members. They can also reduce staff absenteeism, increase productivity, reduce costs associated with health care and disability, and foster a climate that promotes good health schoolwide. An…

  14. Identification and characterization of PhoP regulon members in Yersinia pestis biovar Microtus

    Directory of Open Access Journals (Sweden)

    Du Zongmin

    2008-03-01

    Full Text Available Abstract Background The transcription regulator PhoP has been shown to be important for Y. pestis survival in macrophages and under various in vitro stresses. However, the mechanism by which PhoP promotes bacterial intracellular survival is not fully understood. Our previous microarray analysis suggested that PhoP governed a wide set of cellular pathways in Y. pestis. A series of biochemical experiments were done herein to study members of the PhoP regulon of Y. pestis biovar Microtus. Results By using gel mobility shift assay and quantitative RT-PCR, a total of 30 putative transcription units were characterized as direct PhoP targets. The primer extension assay was further used to determine the transcription start sites of 18 PhoP-dependent promoters and to localize the -10 and -35 elements. The DNase I footprinting was used to identify the PhoP-binding sites within 17 PhoP-dependent promoters, enabling the identification of PhoP box and matrix that both represented the conserved signals for PhoP recognition in Y. pestis. Data presented here providing a good basis for modeling PhoP-promoter DNA interactions that is crucial to the PhoP-mediated transcriptional regulation. Conclusion The proven direct PhoP targets include nine genes encoding regulators and 21 genes or operons with functions of detoxification, protection against DNA damages, resistance to antimicrobial peptides, and adaptation to magnesium limitation. We can presume that PhoP is a global regulator that controls a complex regulatory cascade by a mechanism of not only directly controlling the expression of specific genes, but also indirectly regulating various cellular pathways by acting on a set of dedicated regulators. These results help us gain insights into the PhoP-dependent mechanisms by which Y. pestis survives the antibacterial strategies employed by host macrophages.

  15. Testes de função pulmonar no transplante de medula óssea: Revisão sistemática

    Directory of Open Access Journals (Sweden)

    Eliane Viana Mancuso

    2006-01-01

    Full Text Available Resumo: As complicações pulmonares constituem causa importante de morbidade e mortalidade em doentes submetidos a transplante de medula óssea. Os testes de função pulmonar são utilizados rotineiramente na avaliação antes e no acompanhamento após o transplante. A revisão sistemática da literatura mostrou que a presença de alterações nos testes de função pulmonar antes do transplante de medula não esteve relacionada com maior incidência de complicações pulmonares pós-transplante. Entretanto, alterações destes testes após o transplante estiveram relacionadas com maior incidência de complicações respiratórias. Desta forma, embora as alterações dos testes de função pulmonar pré-transplante não tenham sido de valor preditivo positivo na detecção precoce de complicações respiratórias pós-transplante, os mesmos podem ser úteis na comparação com os testes realizados após o transplante e devem fazer parte da avaliação de doentes candidatos ao transplante de medula óssea.Rev Port Pneumol 2006; XII (1: 61-69 Abstract: The pulmonary function test plays an important role in the management of pulmonary complications after bone marrow transplantation. Although its utility in helping to predict the likelihood of developing post transplant pulmonary complications and mortality is not well established, current data indicate that pre-transplant pulmonary function tests are important as a reference for the interpretation of post transplant pulmonary function tests and for identifying patients at high risk of developing pulmonary complications and/or mortality after bone marrow transplantation.Rev Port Pneumol 2006; XII (1: 61-69 Palavras-chave: Transplante de medula óssea, testes de função pulmonar, revisão sistemática, Key-words: Bone marrow transplantation, respiratory function tests, systematic review

  16. Efeito de um programa escolar de estimulação motora sobre desempenho da função executiva e atenção em crianças

    Directory of Open Access Journals (Sweden)

    Cintia Mota Cardeal

    2013-10-01

    Full Text Available A influência da atividade física escolar no desenvolvimento da função executiva infantil ainda não é consenso entre os estudos já realizados, portanto esse estudo tem como objetivo verificar o efeito da estimulação motora, nas respostas da função cognitiva de crianças na faixa etária de 6 a 10 anos, de escolas públicas do Distrito Federal, Brasil. Foram formados 2 grupos controle (n = 40 e experimental (n = 40, avaliados antes e depois da intervenção, as variáveis analisadas: motricidade, função executiva, tempo de reação e atenção seletiva. A intervenção ocorreu durante 7 meses com aulas de educação física escolar. Os resultados demonstraram que ocorreu uma diferença significativa entre os grupos nos testes de função executiva [F(1, 118 = 13.768; p = .001], tempo de reação [F(1, 118 = 18.352; p = .001] e atenção seletiva [F(1, 64 = 14.531; p = .001]. Desse modo, foi observado que, o grupo que sofreu intervenção melhorou não somente o aspecto motor, mas também melhorou de forma significativa o desempenho das funções cognitivas testadas.

  17. Predictors of job satisfaction among academic faculty members: do instructional and clinical staff differ?

    Science.gov (United States)

    Chung, Kevin C; Song, Jae W; Kim, H Myra; Woolliscroft, James O; Quint, Elisabeth H; Lukacs, Nicholas W; Gyetko, Margaret R

    2010-10-01

    This study aimed to identify and compare predictors of job satisfaction between instructional and clinical faculty members. A 61-item faculty job satisfaction survey was distributed to 1898 academic faculty members at the University of Michigan Medical School. The anonymous survey was web-based. Questions covered topics on departmental organisation, research, clinical and teaching support, compensation, mentorship, and promotion. Levels of satisfaction were contrasted between faculty members on the two tracks, and predictors of job satisfaction were identified using linear regression models. Response rates for the instructional and clinical faculty groups were 43.1% and 46.7%, respectively. Clinical faculty members reported being less satisfied with how they were mentored and fewer reported understanding the process for promotion. There was no significant difference in overall job satisfaction between the two faculty groups. Surprisingly, clinical faculty members with mentors were significantly less satisfied with how they were mentored and with career advancement, and were significantly less likely to choose an academic career if they had to do it all over again compared with instructional faculty mentees. Additionally, senior-level clinical faculty members were significantly less satisfied with their opportunities to mentor junior faculty members compared with senior-level instructional faculty staff. Significant predictors of job satisfaction for both groups included areas of autonomy, meeting career expectations, work-life balance, and departmental leadership. In the clinical track only, compensation and career advancement variables also emerged as significant predictors of overall job satisfaction. Greater emphasis must be placed on faculty members' well-being at both the institutional level and the level of departmental leadership. Efforts to enhance job satisfaction and improve retention are more likely to succeed if they are directed by locally designed

  18. Alterações das funções executivas em crianças e adolescentes

    Directory of Open Access Journals (Sweden)

    Natália Martins Dias

    2010-05-01

    Full Text Available Funções executivas constituem um conjunto de processos cognitivos que permitem a regulação da cognição e do comportamento, possibilitando o engajamento do indivíduo em ações complexas. Essas habilidades estão comprometidas em uma diversidade de condições clínicas e este artigo teórico teve como objetivo oferecer uma revisão não-sistemática de alguns quadros nos quais estas habilidades apresentam-se prejudicadas, sobretudo em crianças e adolescentes. Verificou-se que condições como transtorno do déficit de atenção e hiperatividade, transtorno obsessivo-compulsivo, síndrome de Tourette, transtornos globais do desenvolvimento, transtornos de aprendizagem como a dislexia e a discalculia, além de alterações cromossômicas, como a síndrome de Down e de Prader-Willi, cursam com algum grau de comprometimento do funcionamento executivo. Este conhecimento tem implicações à prática e à pesquisa psicológica e pode ser útil a profissionais que atuam com crianças e adolescentes com alguma destas condições, contribuindo a um maior conhecimento acerca das funções executivas e suas alterações.

  19. Does the Animal Fun program improve motor performance in children aged 4-6 years?

    Science.gov (United States)

    Piek, J P; McLaren, S; Kane, R; Jensen, L; Dender, A; Roberts, C; Rooney, R; Packer, T; Straker, L

    2013-10-01

    The Animal Fun program was designed to enhance the motor ability of young children by imitating the movements of animals in a fun, inclusive setting. The efficacy of this program was investigated through a randomized controlled trial using a multivariate nested cohort design. Pre-intervention scores were recorded for 511 children aged 4.83 years to 6.17 years (M=5.42 years, SD=3.58 months). Six control and six intervention schools were compared 6 months later following the intervention, and then again at 18 months after the initial testing when the children were in their first school year. Changes in motor performance were examined using the Bruininks-Oseretsky Test of Motor Proficiency short form. Data were analyzed using multi-level-mixed effects linear regression. A significant Condition×Time interaction was found, F(2,1219)=3.35, p=.035, demonstrating that only the intervention group showed an improvement in motor ability. A significant Sex×Time interaction was also found, F(2,1219)=3.84, p=.022, with boys improving over time, but not girls. These findings have important implications for the efficacy of early intervention of motor skills and understanding the differences in motor performance between boys and girls. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Using a qualitative approach for understanding hospital-affiliated integrated clinical and fitness facilities: characteristics and members' experiences.

    Science.gov (United States)

    Yang, Jingzhen; Kingsbury, Diana; Nichols, Matthew; Grimm, Kristin; Ding, Kele; Hallam, Jeffrey

    2015-06-19

    With health care shifting away from the traditional sick care model, many hospitals are integrating fitness facilities and programs into their clinical services in order to support health promotion and disease prevention at the community level. Through a series of focus groups, the present study assessed characteristics of hospital-affiliated integrated facilities located in Northeast Ohio, United States and members' experiences with respect to these facilities. Adult members were invited to participate in a focus group using a recruitment flyer. A total of 6 focus groups were conducted in 2013, each lasting one hour, ranging from 5 to 12 participants per group. The responses and discussions were recorded and transcribed verbatim, then analyzed independently by research team members. Major themes were identified after consensus was reached. The participants' average age was 57, with 56.8% currently under a doctor's care. Four major themes associated with integrated facilities and members' experiences emerged across the six focus groups: 1) facility/program, 2) social atmosphere, 3) provider, and 4) member. Within each theme, several sub-themes were also identified. A key feature of integrated facilities is the availability of clinical and fitness services "under one roof". Many participants remarked that they initially attended physical therapy, becoming members of the fitness facility afterwards, or vice versa. The participants had favorable views of and experiences with the superior physical environment and atmosphere, personal attention, tailored programs, and knowledgeable, friendly, and attentive staff. In particular, participants favored the emphasis on preventive care and the promotion of holistic health and wellness. These results support the integration of wellness promotion and programming with traditional medical care and call for the further evaluation of such a model with regard to participants' health outcomes.

  1. Evaluation of Faculty Members by Students in Birjand University of Medicine, 2003-2004

    Directory of Open Access Journals (Sweden)

    Masood Ziaie

    2009-02-01

    Full Text Available Background and purpose: Evaluation of faculty members is a kind of educational evaluation to determine success of faculty members in reaching the educational goals. Regarding the controversy about the validity of this kind of evaluation, this study was done to examine faculty members and students view point about content and implementation of evaluation of faculty members by students and feedback of the results in the second term of academic year 2003-4 in Birjand University of Medicine.Methods: All faculty members and students participated in this descriptive study. Their opinions were studied using two questionnaires for students and faculty members separately, whose content validity were confirmed after a survey from specialists and pilot study and reliability of results werestudied through calculating Cronbach’s alpha coefficient for internal consistency .Data were analyzed through calculating frequencies and K2-test, α=0.05.Results: Of all faculty members, 95% ( 30 from clinical and 30 from non clinical departments were aware of having been evaluated by students, 81.7% of them recognize educational development center of the University as the responsible body for evaluation. 91.7% of them received the feedback of the evaluation results. 45% of them agreed that announcement of evaluation results was helpful to improve teaching. 40% believed that questionnaires were responded without dutifulness andcarefulness by students.Conclusion: The aim of teaching evaluation is to improve teaching by faculty members. But it seems that many faculty members do not regard this evaluation tool so valid for measuring their teaching activities. The inappropriateness of most of the questionnaires, unfair judgment of student, and careless selection of the sample of students who answer the questionnaires are major issues for further development.Key words: EVALUATION, FACULTY MEMBER, STUDENT, MEDICAL UNIVERSITY OF BIRJAND

  2. Developing the fun and educative module in plant morphology and anatomy learning for tenth graders

    Directory of Open Access Journals (Sweden)

    Alfi Suciyati

    2018-03-01

    Full Text Available This research aims to examine the eligibility of and responses from expert media, expert material, practitioners and students’ on the ‘Fun and Educative’ biology module. The module was developed in a fun and educative way presenting various educative games. The research development model is using ADDIE model that consists of five phases: Analysis, Design, Development, Implementation, and Evaluation. The data collection technique employed examination of learning media experts, material experts, practitioners (biology teachers, and students. The data of research was analyzed in descriptive-qualitative and descriptive-qualitative ways. The results of evaluation on the module’s eligibility convey that the learning media expert gave 87.69% with the category of ‘highly eligible’, the material expert gave 86.00% with the category of ‘highly eligible', and the practitioners gave 83.68% with the category of ‘eligible'. The students' responses to questionnaires given related to the developed module gave 90.00% with the category of ‘highly interesting'. Based on the results of examination by the media expert, material expert, practitioners, and students, conclude that the module has fulfilled the criteria of good and eligible learning material and can be used for studying biology.

  3. Função sexual de homens submetidos a transplante hepático Sexual function of males subjected to liver transplantation

    Directory of Open Access Journals (Sweden)

    Júlio Cezar Uili Coelho

    2003-01-01

    Full Text Available OBJETIVO: Avaliar a qualidade de vida sexual masculina antes e depois do transplante hepático. MÉTODOS: Foi enviado questionário de avaliação para 56 doentes masculinos, que tinham idade superior a 18 anos e que sobreviveram mais de seis meses após o transplante hepático. O questionário continha 15 perguntas com cinco ou seis alternativas de resposta para mensurar a função sexual masculina segmentada por cinco componentes: função erétil, função orgástica, desejo sexual, satisfação com a relação sexual e satisfação com a vida sexual como um todo. As respostas geraram valores numéricos, os quais foram agrupados dentro de cada domínio e comparados antes e depois do transplante hepático. RESULTADOS: Vinte e cinco doentes responderam completamente o questionário. Todas os cinco componentes da função sexual melhoraram após o transplante hepático, sendo que o escore da função erétil aumentou de 21,12±8,07 para 26,52±5,22 (p=0,004, da função orgástica de 7,28±3,05 para 9,36±1,47 (p=0,008, da função desejo sexual de 6,64±2,58 para 8,68±1,35 (p=0,005, da satisfação com relação sexual de 9,16±3,83 para 12,52±2,65 (pBACKGROUND: Sexual dysfunction is very common in liver transplantation candidates. Our objective is to determine the sexual life quality of males before and after liver transplantation. METHODS: Questionnaire was sent to 56 males over 18 years of age with at least six-month survival after orthotopic liver transplantation. The self-administered questionnaire contained 15 questions with 5 or 6 alternatives to determine the male sexual function which may be divided into 5 domains: 1 erectile function; 2 orgasmic function; 3 sexual desire; 4 intercourse satisfaction; and 5 overall satisfaction with sexual life. Each answer received a score. Domains scores were computed by summing the scores for individual answers and they were compared before and after the liver transplantation. RESULTS: Twenty

  4. 7 CFR 1216.30 - United States.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1216.30 Section 1216.30 Agriculture... INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.30 United States. United States means collectively the 50 states, the District of Columbia, the Commonwealth of Puerto Rico...

  5. Relação entre o perfil funcional, função motora grossa e habilidade manual dos alunos com paralisia cerebral

    Directory of Open Access Journals (Sweden)

    Fernanda Matrigani Mercado Gutierres de Queiroz

    2016-03-01

    Full Text Available A inclusão tem se tornado elemento chave da política educacional. Para atender aos alunos com deficiências, transtornos globais do desenvolvimento e altas habilidades/superdotação, foi instituído o Atendimento Educacional Especializado (AEE. Para que se possa respaldar o trabalho pedagógico com recursos e ações que possibilitem ao aluno com Paralisia Cerebral (PC participar junto aos demais e demonstrar seu potencial, é relevante estudar a relação entre o perfil funcional, a função motora grossa e as habilidades manuais do aluno com PC. O objetivo deste estudo é verificar se há relação entre a funcionalidade no ambiente escolar e o nível de comprometimento de função motora grossa e habilidade manual em alunos com PC. As participantes desta pesquisa foram seis professoras do AEE, que forneceram informações para a avaliação School Function Assessment (SFA, Sistema de Classificação da função motora grossa (GMFCS e Sistema de Classificação da Habilidade Manual (MACS de dez alunos com Paralisia Cerebral. Verificou-se haver uma correlação forte e positiva entre diversas das variáveis estudadas e correlação forte e negativa entre outras delas. Os achados revelam que há relação entre a funcionalidade no ambiente escolar e o nível de comprometimento de função motora grossa e habilidade manual em alunos com PC.

  6. Experiences of Academic Members About their Professional Challenges: a Content Analysis Qualitative study.

    Science.gov (United States)

    Shahhosseini, Zohreh; Danesh, Mahmonier

    2014-04-01

    University faculty members of different disciplines in any country, by giving better quality services, will further accelerate the development of their respective countries. This study aims to explore the experiences of faculty members about their professional challenges. In this qualitative study, which was conducted in 2013, fifteen faculty members in the departments of clinical and basic sciences of Mazandaran university of Medical Sciences in northern Iran were chosen for semi-structured in-depth interviews by purposive sampling method. All tape-recorded data were fully transcribed and content analysis was performed. AFTER IMMERSION AND DATA ANALYSIS, THREE MAIN THEMES WERE EMERGED INCLUDING: "Imbalances in academic members' tasks in different areas", "Weakness of evaluation and promotion system" and "Failure to provide the infrastructure educational facilities". The main themes and sub-themes are explained by the help of participants' direct quotations. This study suggested that it is better to take effective measures to improve the faculty members' situation and therefore increase their efficiency, effectiveness and productivity.

  7. Knowledge of Dementia: Do family members understand dementia as a terminal condition?

    Science.gov (United States)

    Andrews, Sharon; McInerney, Fran; Toye, Christine; Parkinson, Camillus-Anthony; Robinson, Andrew

    2017-07-01

    Current research identifies advanced dementia to be the terminal phase of this progressive and incurable condition. However, there has been relatively little investigation into how family members of people with advanced dementia understand their relative's condition. In this article, we report on semi-structured interviews with 10 family members of people with advanced dementia, in a residential aged care facility. Using a qualitative, descriptive design, we explored family members' understandings of dementia, whether they were aware that it was a terminal condition, and the ways they developed their understandings. Findings revealed that the majority of family members could not recognize the terminal nature of dementia. Relying on predominantly lay understandings, they had little access to formal information and most failed to conceptualize a connection between dementia and death. Moreover, family members engaged in limited dialogue with aged care staff about such issues, despite their relatives being in an advanced stage of the disease. Findings from our study suggest that how family members understand their relative's condition requires greater attention. The development of staff/family partnerships that promote shared communication about dementia and dying may enhance family members' understandings of the dementia trajectory and the types of decisions they may be faced with during the more advanced stages of the disease.

  8. Emerald Dragon Bites vs Veggie Beans: Fun Food Names Increase Children's Consumption of Novel Healthy Foods

    Science.gov (United States)

    Musher-Eizenman, Dara R.; Oehlhof, Marissa Wagner; Young, Kathleen M.; Hauser, Jessica C.; Galliger, Courtney; Sommer, Alyssa

    2011-01-01

    Caregivers often struggle with food neophobia on the part of young children. This study examined whether labeling novel healthy foods with fun names would increase children's willingness to try those foods and encourage them to eat more of those foods in a child care setting. Thirty-nine toddler and preschool age children (mean age = 3.9 years)…

  9. Promotion Criteria and Satisfaction of School Teachers in Hong Kong

    Science.gov (United States)

    Wong, Ping-Man; Wong, Chi-Sum

    2005-01-01

    Teacher promotion is an important issue in school administration that deserves more academic attention. In business management a commonly used tool for employee motivation, aside from promotion, is the compensation system, which can be flexibly and frequently adjusted with the performance of individual staff members. However, in the existing…

  10. Damage Model of Reinforced Concrete Members under Cyclic Loading

    Science.gov (United States)

    Wei, Bo Chen; Zhang, Jing Shu; Zhang, Yin Hua; Zhou, Jia Lai

    2018-06-01

    Based on the Kumar damage model, a new damage model for reinforced concrete members is established in this paper. According to the damage characteristics of reinforced concrete members subjected to cyclic loading, four judgment conditions for determining the rationality of damage models are put forward. An ideal damage index (D) is supposed to vary within a scale of zero (no damage) to one (collapse). D should be a monotone increasing function which tends to increase in the case of the same displacement amplitude. As for members under large displacement amplitude loading, the growth rate of D should be greater than that of D under small amplitude displacement loading. Subsequently, the Park-Ang damage model, the Niu-Ren damage model, the Lu-Wang damage model and the proposed damage model are analyzed for 30 experimental reinforced concrete members, including slabs, walls, beams and columns. The results show that current damage models do not fully matches the reasonable judgment conditions, but the proposed damage model does. Therefore, a conclusion can be drawn that the proposed damage model can be used for evaluating and predicting damage performance of RC members under cyclic loading.

  11. Rationale, design and methods for a randomised and controlled trial to evaluate "Animal Fun" - a program designed to enhance physical and mental health in young children

    Directory of Open Access Journals (Sweden)

    McLaren Sue

    2010-11-01

    Full Text Available Abstract Background Children with poor motor ability have been found to engage less in physical activities than other children, and a lack of physical activity has been linked to problems such as obesity, lowered bone mineral density and cardiovascular risk factors. Furthermore, if children are confident with their fine and gross motor skills, they are more likely to engage in physical activities such as sports, crafts, dancing and other physical activity programs outside of the school curriculum which are important activities for psychosocial development. The primary objective of this project is to comprehensively evaluate a whole of class physical activity program called Animal Fun designed for Pre-Primary children. This program was designed to improve the child's movement skills, both fine and gross, and their perceptions of their movement ability, promote appropriate social skills and improve social-emotional development. Methods The proposed randomized and controlled trial uses a multivariate nested cohort design to examine the physical (motor coordination and psychosocial (self perceptions, anxiety, social competence outcomes of the program. The Animal Fun program is a teacher delivered universal program incorporating animal actions to facilitate motor skill and social skill acquisition and practice. Pre-intervention scores on motor and psychosocial variables for six control schools and six intervention schools will be compared with post-intervention scores (end of Pre-Primary year and scores taken 12 months later after the children's transition to primary school Year 1. 520 children aged 4.5 to 6 years will be recruited and it is anticipated that 360 children will be retained to the 1 year follow-up. There will be equal numbers of boys and girls. Discussion If this program is found to improve the child's motor and psychosocial skills, this will assist in the child's transition into the first year of school. As a result of these changes

  12. Music for Social Occasions - Music for Fun, Music for Every Day, Lublaň 21.-23. června 2006

    Czech Academy of Sciences Publication Activity Database

    Bajgarová, Jitka

    2006-01-01

    Roč. 43, č. 3 (2006), s. 335-336 ISSN 0018-7003. [ Music for Social Occasions - Music for Fun, Music for Every Day. Ljubljana, 210606-230606] Institutional research plan: CEZ:AV0Z90580513 Keywords : Music * social occasions Subject RIV: AL - Art, Architecture, Cultural Heritage

  13. Identification of a functional element in the promoter of the silkworm (Bombyx mori) fat body-specific gene Bmlp3.

    Science.gov (United States)

    Xu, Hanfu; Deng, Dangjun; Yuan, Lin; Wang, Yuancheng; Wang, Feng; Xia, Qingyou

    2014-08-01

    30K proteins are a group of structurally related proteins that play important roles in the life cycle of the silkworm Bombyx mori and are largely synthesized and regulated in a time-dependent manner in the fat body. Little is known about the upstream regulatory elements associated with the genes encoding these proteins. In the present study, the promoter of Bmlp3, a fat body-specific gene encoding a 30K protein family member, was characterized by joining sequences containing the Bmlp3 promoter with various amounts of 5' upstream sequences to a luciferase reporter gene. The results indicated that the sequences from -150 to -250bp and -597 to -675bp upstream of the Bmlp3 transcription start site were necessary for high levels of luciferase activity. Further analysis showed that a 21-bp sequence located between -230 and -250 was specifically recognized by nuclear factors from silkworm fat bodies and BmE cells, and could enhance luciferase reporter-gene expression 2.8-fold in BmE cells. This study provides new insights into the Bmlp3 promoter and contributes to the further clarification of the function and developmental regulation of Bmlp3. Copyright © 2014. Published by Elsevier B.V.

  14. Pharmacy practice department chairs' perspectives on part-time faculty members.

    Science.gov (United States)

    Fjortoft, Nancy; Winkler, Susan R; Mai, Thy

    2012-05-10

    To identify the benefits and consequences of having part-time faculty members in departments of pharmacy practice from the department chair's perspective. A stratified purposive sample of 12 pharmacy practice department chairs was selected. Eleven telephone interviews were conducted. Two investigators independently read interview notes and categorized and enumerated responses to determine major themes using content analysis. The investigators jointly reviewed the data and came to consensus on major themes. Benefits of allowing full-time faculty members to reduce their position to part-time included faculty retention and improved individual faculty work/life balance. Consequences of allowing part-time faculty positions included the challenges of managing individual and departmental workloads, the risk of marginalizing part-time faculty members, and the challenges of promotion and tenure issues. All requests to switch to part-time status were faculty-driven and most were approved. There are a variety of benefits and consequences of having part-time faculty in pharmacy practice departments from the chair's perspective. Clear faculty and departmental expectations of part-time faculty members need to be established to ensure optimal success of this working arrangement.

  15. Pharmacy Practice Department Chairs’ Perspectives on Part-Time Faculty Members

    Science.gov (United States)

    Winkler, Susan R.; Mai, Thy

    2012-01-01

    Objective. To identify the benefits and consequences of having part-time faculty members in departments of pharmacy practice from the department chair’s perspective. Methods. A stratified purposive sample of 12 pharmacy practice department chairs was selected. Eleven telephone interviews were conducted. Two investigators independently read interview notes and categorized and enumerated responses to determine major themes using content analysis. The investigators jointly reviewed the data and came to consensus on major themes. Results. Benefits of allowing full-time faculty members to reduce their position to part-time included faculty retention and improved individual faculty work/life balance. Consequences of allowing part-time faculty positions included the challenges of managing individual and departmental workloads, the risk of marginalizing part-time faculty members, and the challenges of promotion and tenure issues. All requests to switch to part-time status were faculty-driven and most were approved. Conclusions. There are a variety of benefits and consequences of having part-time faculty in pharmacy practice departments from the chair’s perspective. Clear faculty and departmental expectations of part-time faculty members need to be established to ensure optimal success of this working arrangement. PMID:22611268

  16. Executive functions for Learning and decision-making in a bio-inspired cognitive architecture = : Funções executivas para aprendizado e tomada de decisão em uma arquitetura cognitiva bio-inspirada

    OpenAIRE

    Klaus Raizer

    2015-01-01

    Resumo: O objetivo deste trabalho é o desenvolvimento de funções executivas para uma arquitetura cognitiva bioinspirada baseada em codelets. Um desafio que toda criatura (seja ela artificial ou biológica) enfrenta é definir qual a próxima ação a ser tomada, a cada instante de tempo, em função da percepção de um determinado ambiente. Essa decisão pode ser definida por um algoritmo que sempre repete as mesmas decisões em função de uma determinada situação, ou pode ser uma decisão adaptativa, qu...

  17. Uncertainty Quantification of the FUN3D-Predicted NASA CRM Flutter Boundary

    Science.gov (United States)

    Stanford, Bret K.; Massey, Steven J.

    2017-01-01

    A nonintrusive point collocation method is used to propagate parametric uncertainties of the flexible Common Research Model, a generic transport configuration, through the unsteady aeroelastic CFD solver FUN3D. A range of random input variables are considered, including atmospheric flow variables, structural variables, and inertial (lumped mass) variables. UQ results are explored for a range of output metrics (with a focus on dynamic flutter stability), for both subsonic and transonic Mach numbers, for two different CFD mesh refinements. A particular focus is placed on computing failure probabilities: the probability that the wing will flutter within the flight envelope.

  18. 77 FR 55180 - Request for Nominations of Members To Serve on the Federal Economic Scientific Advisory Committee

    Science.gov (United States)

    2012-09-07

    ... (SGEs) and are subject to ethics rules applicable to SGEs. b. Members serve three-year terms. Members... equal opportunity in the workplace and seeks diverse Committee membership. Dated: August 30, 2012...

  19. Recuperação espontanea da função nas lesões do sistema nervoso central Spontaneous recuperation of function in central nervous system lesions

    Directory of Open Access Journals (Sweden)

    Abrão Anghinah

    1975-12-01

    Full Text Available É feita uma revisão dos mecanismos apontados como responsáveis pela recuperação espontânea da função em pacientes com lesões do sistema nervoso central. São referidas as teorias de reorganização espontânea do tecido nervoso e da função vicariante. É destacada a contribuição experimental das duas últimas décadas, particularmente a dos pesquisadores encabeçados por Windle & Guth, que demonstraram a possibilidade de regeneração no sistema nervoso central, bem como as de Lawrence & Kuypers, Brodal & Goldberger, que advogam a função vicariante como mecanismo provável da recuperação da função.A rewiev of the mechanims responsible for the spontaneous recuperation of function in patients with lesions of the central nervous sistem is made. The spontaneous reorganization theories of the nervous structures and the vicarious function are also referred to. In the last two decades experimental contributions have been accentuated, specially the one conducted by the group of researchers directed by Windle and Guth, who had shown the possibility of regeneration in the central nervous system, as well Lawrende and Kuypers, Brodal, Goldberger and others, which defended the vicarious function as the probable mechanisms of recuperation.

  20. The importance of older family members in providing social resources and promoting cancer screening in families with a hereditary cancer syndrome.

    Science.gov (United States)

    Ashida, Sato; Hadley, Donald W; Goergen, Andrea F; Skapinsky, Kaley F; Devlin, Hillary C; Koehly, Laura M

    2011-12-01

    This study evaluates the role of older family members as providers of social resources within familial network systems affected by an inherited cancer susceptibility syndrome.  Respondents who previously participated in a study that involved genetic counseling and testing for Lynch syndrome and their family network members were invited to participate in a onetime telephone interview about family communication. A total of 206 respondents from 33 families identified 2,051 social relationships (dyads). Nineteen percent of the respondents and 25% of the network members were older (≥60 years). Younger respondents (≤59 years) were more likely to nominate older network members as providers of social resources than younger members: instrumental support (odds ratio [OR] = 1.68), emotional support (OR = 1.71), help in crisis situation (OR = 2.04), and dependability when needed (OR = 2.15). Compared with younger network members, older members were more likely to be listed as encouragers of colon cancer screening by both younger (OR = 3.40) and older respondents (OR = 1.90) independent of whether support exchange occurred in the relationship. Engaging older network members in health interventions to facilitate screening behaviors and emotional well-being of younger members within families affected by inherited conditions may be beneficial. Findings can be used to empower older individuals about their important social roles in enhancing the well-being of their family members and to inform younger individuals about their older relatives' resourcefulness to facilitate positive social interactions.

  1. Marketingová strategie lyžařské školy School 4 fun.

    OpenAIRE

    Burešová, Eva

    2011-01-01

    The aim of diploma thesis is to suggest new marketing strategy of ski and snowboard school SCHOOL 4 FUN for this year 2011/2012 including proposals and recommendation for its improvement. Suggested marketing strategy is the solution for suitable position of limited financial means for the company to maintain competitive advantage, increase its sale, thus increase its revenue at the same time. To achieve given aim, the technique of competitive analysis, marketing mix and SWOT analysis was used...

  2. Agreement on the Privileges and Immunities of the Agency. Acceptances by Member States

    International Nuclear Information System (INIS)

    1973-01-01

    The list of Member States overleaf shows the 41 Members which, by 30 November 1972, had accepted the Agreement on the Privileges and Immunities of the International Atomic Energy Agency, as provided for in Section 38 thereof. Members are listed in alphabetical order, which is different in versions of this document in other languages. The list is followed by the texts of such reservations to the Agreement as some of the Members in question made when depositing their respective instruments of acceptance with the Director General. The reservations are reproduced in the sequence in which the instruments of acceptance to which they relate were deposited

  3. Agreement on the Privileges and Immunities of the Agency. Acceptances by Member States

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1973-01-15

    The list of Member States overleaf shows the 41 Members which, by 30 November 1972, had accepted the Agreement on the Privileges and Immunities of the International Atomic Energy Agency, as provided for in Section 38 thereof. Members are listed in alphabetical order, which is different in versions of this document in other languages. The list is followed by the texts of such reservations to the Agreement as some of the Members in question made when depositing their respective instruments of acceptance with the Director General. The reservations are reproduced in the sequence in which the instruments of acceptance to which they relate were deposited.

  4. 30 Ways to Build Your Center's Enrollment.

    Science.gov (United States)

    Child Care Information Exchange, 1991

    1991-01-01

    The Exchange Panel of 100 Members shares ideas for building enrollment in day care centers. Suggestions include stimulating communication with parents and promoting word-of-mouth referrals, offering visits and child care to prospective clients, sponsoring community activities, and serving as a source of child development expertise. (SH)

  5. Offers for our members

    CERN Multimedia

    Staff Association

    2013-01-01

    The warm weather arrives, it's time to take advantage of our offers Walibi and Aquapark! Walibi : Tickets "Zone terrestre": 21 € instead of 26 € Access to Aqualibi: 5 € instead of 8 € on presentation of your SA member ticket. Free for children (3-11 years old) before 12 h 00. Free for children under 3, with limited access to the attractions. Car park free. * * * * * Aquaparc : Half-day ticket (5 hours): – Children: 26 CHF instead of 35 CHF – Adults : 32 CHF instead of 43 CHF Day ticket: – Children: 30 CHF instead of 39 CHF – Adults : 36 CHF instead of 49 CHF Free for children under 5.

  6. Memória de trabalho e função executiva – uma proposta de diálogo entre dois modelos teóricos

    OpenAIRE

    Melo, Luciene Bandeira Rodrigues de

    2011-01-01

    A classificação de função executiva, que corresponde a um sistema gerenciador que tem como atributo organizar uma sequência de ações a fim de atingir um objetivo, tem sido amplamente estudada por dois conceituados autores, quais sejam, Joaquin Fuster e Alan Baddeley. O objetivo deste trabalho teórico é propor uma fusão entre as ideias destes dois neurocientistas. Fuster postulou que a função executiva opera por meio de redes neurais interativas e sobrepostas (cógnitos), distribuídas nos córti...

  7. Sobre o pai da criança atendida na escola e sua função

    Directory of Open Access Journals (Sweden)

    Sonia Alberti

    Full Text Available O pai da função paterna (conceitualizada por Jacques Lacan não é o mesmo ao qual educadores fazem apelo quando se queixam das condutas dos pais, de suas ausências ou atuações. No entanto, o fato de haver queixas quanto aos pais não deixa de apontar uma intuição da importância do pai na educação da criança.O texto visa verificar a relação dessa intuição, suas balizas históricas, com as contribuições da clínica psicanalítica, para articulá-la com a época atual e examiná-la à luz da função paterna determinada como conceito, conseqüência do complexo de Édipo em Freud. Por essa razão, esperamos poder contribuir na intersecção de duas áreas de atuação: a clínica e a escola, o que se justifica também pela nossa própria experiência com as questões lançadas.

  8. Oxytocin promotes group-serving dishonesty.

    Science.gov (United States)

    Shalvi, Shaul; De Dreu, Carsten K W

    2014-04-15

    To protect and promote the well-being of others, humans may bend the truth and behave unethically. Here we link such tendencies to oxytocin, a neuropeptide known to promote affiliation and cooperation with others. Using a simple coin-toss prediction task in which participants could dishonestly report their performance levels to benefit their group's outcome, we tested the prediction that oxytocin increases group-serving dishonesty. A double-blind, placebo-controlled experiment allowing individuals to lie privately and anonymously to benefit themselves and fellow group members showed that healthy males (n = 60) receiving intranasal oxytocin, rather than placebo, lied more to benefit their group, and did so faster, yet did not necessarily do so because they expected reciprocal dishonesty from fellow group members. Treatment effects emerged when lying had financial consequences and money could be gained; when losses were at stake, individuals in placebo and oxytocin conditions lied to similar degrees. In a control condition (n = 60) in which dishonesty only benefited participants themselves, but not fellow group members, oxytocin did not influence lying. Together, these findings fit a functional perspective on morality revealing dishonesty to be plastic and rooted in evolved neurobiological circuitries, and align with work showing that oxytocin shifts the decision-maker's focus from self to group interests. These findings highlight the role of bonding and cooperation in shaping dishonesty, providing insight into when and why collaboration turns into corruption.

  9. Prognostic values of soluble CD30 and CD30 gene polymorphisms in heart transplantation.

    Science.gov (United States)

    Frisaldi, Elisa; Conca, Raffaele; Magistroni, Paola; Fasano, Maria Edvige; Mazzola, Gina; Patanè, Francesco; Zingarelli, Edoardo; Dall'omo, Anna M; Brusco, Alfredo; Amoroso, Antonio

    2006-04-27

    Pretransplant soluble CD30 (sCD30) is a predictor of kidney graft outcome. Its status as a predictor of heart transplant (HT) outcome has not been established. We have studied this question by assessing sCD30 levels and the number of (CCAT)n repeats of the microsatellite in the CD30 promoter region, which is able alone to repress gene transcription, in the sera of 83 HT patients and 77 of their donors. sCD30 was non-significantly increased in the patients, whereas there were no differences in the CD30 microsatellite allele frequencies. A negative correlation between the number of (CCAT)n and sCD30 levels was evident in the donors. Patients with pretransplant sCD30sCD30 levels are predictive of HT outcome.

  10. 30 : 2: A Game Designed to Promote the Cardiopulmonary Resuscitation Protocol

    Directory of Open Access Journals (Sweden)

    Imma Boada

    2016-01-01

    Full Text Available Cardiopulmonary resuscitation (CPR is a first-aid key survival technique used to stimulate breathing and keep blood flowing to the heart. Its effective administration can significantly increase the survival chances of cardiac arrest victims. We propose 30 : 2, a videogame designed to introduce the main steps of the CPR protocol. It is not intended for certification and training purpose. Driven by the 2010 European Resuscitation Council guidelines we have designed a game composed of eight mini games corresponding to the main steps of the protocol. The player acts as a helper and has to solve a different challenge. We present a detailed description of the game creation process presenting the requirements, the design decisions, and the implementation details. In addition, we present some first impressions of our testing users (25 children, five of each age from 8 to 12 years old and 12 males and 13 females. We evaluated clarity of instructions and three settings of the game: the aesthetics of scenarios, the playability, and the enjoyability of each mini game. All games were well punctuated, and there are no significantly differences between their sex. The proposed game can be a suitable tool to disseminate and promote CPR knowledge.

  11. Validação do Índice Internacional de Função Erétil (IIFE para uso no Brasil

    Directory of Open Access Journals (Sweden)

    Ana Inês Gonzáles

    2013-08-01

    Full Text Available FUNDAMENTO: O Índice Internacional de Função Erétil tem sido proposto como método de avaliação da função sexual, auxiliando no diagnóstico e na classificação da disfunção erétil. No entanto, não foi realizada a validação do IIFE para a língua portuguesa. OBJETIVO: Validar o Índice Internacional de Função Erétil em pacientes portadores de doenças cardiopulmonares e metabólicas. MÉTODOS: A amostra foi composta por 108 participantes portadores de doenças cardiopulmonares e metabólicas de dois programas de reabilitação cardiopulmonar e metabólica (RCPM do sul do Brasil. A avaliação da clareza do instrumento foi realizada por meio de escala com variação de 0-10, a validação de construto foi realizada pela análise fatorial confirmatória (KMO = 0,85, Barllet p < 0,001, a consistência interna foi analisada pelo alfa de Cronbach. Foram analisados, ainda, os preceitos de reprodutibilidade e confiabilidade interavaliadores por meio do teste reteste. RESULTADOS: Os itens foram julgados muito claros, com médias superiores a 9. A consistência interna resultou em 0,89. A maioria das questões relacionou-se corretamente com seus respectivos domínios, com exceção das três questões do domínio satisfação sexual e uma questão relacionada à função erétil. Os itens apresentaram excelente estabilidade de medida e concordância substancial quase perfeita. CONCLUSÃO: Demonstrou-se que o IIFE é válido e bem compreendido por pacientes que participam de programa de reabilitação cardiopulmonar e metabólica.

  12. Social media use by community-based organizations conducting health promotion: a content analysis.

    Science.gov (United States)

    Ramanadhan, Shoba; Mendez, Samuel R; Rao, Megan; Viswanath, Kasisomayajula

    2013-12-05

    Community-based organizations (CBOs) are critical channels for the delivery of health promotion programs. Much of their influence comes from the relationships they have with community members and other key stakeholders and they may be able to harness the power of social media tools to develop and maintain these relationships. There are limited data describing if and how CBOs are using social media. This study assesses the extent to which CBOs engaged in health promotion use popular social media channels, the types of content typically shared, and the extent to which the interactive aspects of social media tools are utilized. We assessed the social media presence and patterns of usage of CBOs engaged in health promotion in Boston, Lawrence, and Worcester, Massachusetts. We coded content on three popular channels: Facebook, Twitter, and YouTube. We used content analysis techniques to quantitatively summarize posts, tweets, and videos on these channels, respectively. For each organization, we coded all content put forth by the CBO on the three channels in a 30-day window. Two coders were trained and conducted the coding. Data were collected between November 2011 and January 2012. A total of 166 organizations were included in our census. We found that 42% of organizations used at least one of the channels of interest. Across the three channels, organization promotion was the most common theme for content (66% of posts, 63% of tweets, and 93% of videos included this content). Most organizations updated Facebook and Twitter content at rates close to recommended frequencies. We found limited interaction/engagement with audience members. Much of the use of social media tools appeared to be uni-directional, a flow of information from the organization to the audience. By better leveraging opportunities for interaction and user engagement, these organizations can reap greater benefits from the non-trivial investment required to use social media well. Future research should

  13. Avaliação da qualidade de vida e função sexual de mulheres com e sem incontinência urinária

    Directory of Open Access Journals (Sweden)

    Kelly Faria

    2012-06-01

    Full Text Available A incontinência urinária é a queixa de perda involuntária de urina. Os objetivos do presente estudo foram mensurar e comparar a qualidade de vida e a função sexual de mulheres com e sem incontinência urinária. Foram entrevistadas setenta mulheres, com e sem incontinência urinária. Os dados foram coletados por meio dos seguintes instrumentos: WHOQOL-BREF, KHQ e FSFI. Foram realizadas análises descritivas e teste t Student pareado (p<0,05. A qualidade de vida mensurada pelo WHOQOL–BREF evidenciou que as mulheres incontinentes apresentaram média de escore menor (S=57,14 quando comparadas com as continentes (S=71,42. Na avaliação da função sexual, o grupo GI obteve média total de escore menor (S=17,17 quando comparado com o grupo GC (S=24,20. Concluiu-se que tanto na análise da qualidade de vida quanto na função sexual os menores escores foram encontrados no grupo incontinente, evidenciando assim o impacto negativo da incontinência urinária na vida dessas mulheres.

  14. Teaching Case: IS Security Requirements Identification from Conceptual Models in Systems Analysis and Design: The Fun & Fitness, Inc. Case

    Science.gov (United States)

    Spears, Janine L.; Parrish, James L., Jr.

    2013-01-01

    This teaching case introduces students to a relatively simple approach to identifying and documenting security requirements within conceptual models that are commonly taught in systems analysis and design courses. An introduction to information security is provided, followed by a classroom example of a fictitious company, "Fun &…

  15. 12 CFR 208.30 - Authority, purpose, and scope.

    Science.gov (United States)

    2010-01-01

    ...). (b) Purpose and scope. This subpart C describes the requirements imposed upon member banks acting as... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Authority, purpose, and scope. 208.30 Section 208.30 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM...

  16. Promoting Learning in Libraries through Information Literacy.

    Science.gov (United States)

    Breivik, Patricia Senn; Ford, Barbara J.

    1993-01-01

    Discusses information literacy and describes activities under the sponsorship of the National Forum on Information Literacy (NFIL) that promotes information literacy in schools and libraries. Activities of member organizations of the NFIL are described, including policy formation, publications, and programs; and the role of the American Library…

  17. Efeito da obesidade na função ventilatória Impact of obesity on ventilatory function

    Directory of Open Access Journals (Sweden)

    Perran Boran

    2007-04-01

    Full Text Available OBJETIVO: Embora a obesidade tenha sido associada ao comprometimento grave da ventilação, a maior parte da população estudada constitui-se de adultos com obesidade mórbida. Nosso objetivo foi investigar os efeitos da obesidade leve na função ventilatória de pacientes pediátricos. MÉTODOS: Estudo transversal controlado que analisou 80 pacientes (M/F: 35/45 avaliados em nosso ambulatório, com queixa de sobrepeso, sem histórico de asma ou de outras atopias, comparando-os a um grupo controle com 50 crianças de peso normal controladas para a idade e para o sexo. A média de idade dos pacientes foi de 9,7±2,5 anos (7 a 15 anos. Todos os indivíduos foram submetidos a medições antropométricas e à espirometria. A capacidade vital forçada (CVF e o volume expiratório forçado no primeiro segundo (VEF1 foram usados como medidas da função ventilatória. RESULTADOS: Não houve diferenças significativas nas VEF1%, CVF% e VEF1%/CVF% por grupo de estudo (p > 0,05. Apenas três pacientes tiveram alterações obstrutivas relatadas em seus testes de função pulmonar (dois tiveram alterações moderadamente graves e um teve alterações obstrutivas leves. Não houve correlação entre os parâmetros da função pulmonar e as medidas antropométricas. CONCLUSÃO: Esses dados mostram que os parâmetros do teste da função pulmonar em crianças com obesidade leve foram semelhantes àqueles das crianças com peso normal. As medidas antropométricas não mostraram nenhum efeito significativo nas medições espirométricas das crianças, como ocorreu nos adultos.OBJECTIVE: Although obesity was found to be associated with severe impairment of ventilation, most of the study population has been morbidly obese adults. We aimed to explore the effects of mild obesity on ventilatory function in the pediatric age group. METHODS: In a cross-sectional controlled study, 80 patients (M/F: 35/45, who were evaluated in our outpatient clinic with the complaint

  18. A temperature response function for development of the chrysanthemum (Chrysanthemum x morifolium Ramat. Uma função de resposta do desenvolvimento à temperatura em crisântemo (Chrysanthemum x morifolium Ramat.

    Directory of Open Access Journals (Sweden)

    Nereu Augusto Streck

    2004-02-01

    Full Text Available Developmental models can help growers to decide management practices, and to predict flowering and harvest time. Currently, a double exponential function is proposed as a generalized temperature response function for chrysanthemum. This function is not the most appropriate because its parameters lack biological meaning. The objective of this study was to develop a nonlinear temperature response function of chrysanthemum development that has parameters with biological meaning. The proposed function is a beta function with three parameters, the cardinal temperatures (minimum, optimum, and maximum temperatures for development, which were defined as 0, 22, and 35ºC. Published data of temperature response of development of three cultivars, which are independent data sets, were used to test the performance of the double exponential function and the beta function. Results showed that the beta function is better than the double exponential function to describe the temperature response of chrysanthemum development.Modelos de desenvolvimento podem ajudar os produtores no manejo e no planejamento da época de florescimento e colheita. Atualmente, a resposta térmica do desenvolvimento do crisântemo é modelada por uma função exponencial dupla, a qual não é completamente adequada porque os seus parâmetros não têm interpretação biológica. O objetivo deste estudo foi desenvolver uma função de resposta do desenvolvimento à temperatura em crisântemo que tenha parâmetros com interpretação biológica. A função proposta é uma função beta com três parâmetros, que são as temperaturas cardinais (temperaturas mínima, ótima e máxima de desenvolvimento, definidas como 0, 22 e 35ºC. Dados independentes da resposta do desenvolvimento à temperatura em três cultivares de crisântemo publicados na literatura foram usados para testar as duas funções de resposta. Os resultados mostraram que a função beta é melhor do que a fun

  19. The Nordic Health Promotion Research Network (NHPRN).

    Science.gov (United States)

    Ringsberg, Karin C

    2015-08-01

    The Nordic Health Promotion Research Network (NHPRN) was established in 2007 at the Nordic School of Public Health (NHV). This article aims to describe the foundation of the NHPRN, the development and the present status of the work of NHPRN. The NHPRN consists of about 50 senior and junior researchers from all Nordic countries. It is a working network that aims to develop the theoretical understanding of health promotion, to create research cooperation in health promotion from a Nordic perspective and to extend the scope of health promotion through education. Network members meet biannually to discuss and further develop research within the field and are also responsible for the Nordic conference on Health Promotion, organized every 3 years. The NHV hosted the network between 2007 and 2014; and the World Health Organisation (WHO) will assume this role in 2015. © 2015 the Nordic Societies of Public Health.

  20. Promotion and Fast Food Demand: Where's the Beef?

    OpenAIRE

    Richards, Timothy J.; Padilla, Luis

    2007-01-01

    Many believe that fast food promotion is a significant cause of the obesity epidemic in North America. Industry members argue that promotion only reallocates brand shares and does not increase overall demand. This study weighs into the debate by specifying and estimating a discrete/continuous model of fast food restaurant choice and food expenditure that explicitly accounts for both spatial and temporal determinants of demand. Estimates are obtained using a unique panel of Canadian fast food ...

  1. As Relações entre Autismo, Comportamento Social e Função Executiva The Relationship between Autism, Social Behaviour and Executive Function

    Directory of Open Access Journals (Sweden)

    Cleonice Alves Bosa

    2001-01-01

    Full Text Available O objetivo do presente artigo é discutir o papel do lobo frontal nos comportamentos que caracterizam a síndrome do autismo. Focaliza, em especial, as possíveis relações entre função executiva, teoria da mente e habilidade de atenção compartilhada. Conclui-se que, apesar da investigação sobre a hipótese de comprometimento da função executiva como déficit subjacente ao autismo ser uma área promissora, muitas questões ainda permanecem abertas, como por exemplo, a questão da relação causal função executiva-déficit social; dificuldades acerca da especificidade deste comprometimento na área do autismo; a necessidade de investigar-se a natureza e intensidade do comprometimento na função executiva dentro dos subgrupos que compõem o espectro autista e a sobreposição dessa teoria com a de coerência central. Argumenta-se que a discussão sobre relações entre função executiva e comportamento social será incompleta caso não for compreendida a partir de um contexto psicossocial no qual se inserem os indivíduos com autismo e suas famílias.The aim of this paper is to discuss the role of the frontal lobe on the behaviours which characterize the autistic syndrome. The possible relationship between the executive function, theory of mind, and joint attention ability is specially focused. It is concluded that although the investigation of the hypothesis of the executive function underlying the deficts in autism is a promissing area, there are many questions which remain open, such as the causal executive function-social deficit relationship; difficulties regarding the restriction of this deficit to the autism; the need of investigating both the nature and the intensity of the executive function deficits within the subgroups which compound the autistic spectrum area, and the overlap between this theory and the central coherence theory. It is argued that the discussion about the relationship between the executive function and

  2. An understanding of Japanese children's perceptions of fun, barriers, and facilitators of active free play.

    Science.gov (United States)

    Lee, YingHua; Takenaka, Koji; Kanosue, Kazuyuki

    2015-09-01

    Physical activity contributes to children's physical and mental well-being. Research suggests that active free play helps to maintain and increase physical activity in children and also contributes to social and emotional well-being. To date, these studies have focused on Western countries. Thus, this study was conducted to gain insights into the factors of perceptions of fun, barriers, and facilitators affecting active free play from the perspective of Japanese children using focus group interviews. In Japan, 12 focus groups were conducted with 60 children aged 9-11 years. Children's perceptions of fun in active free play were categorized into socializing, achievement, emotions, and freedom. Additionally, active boys' groups were interested in free play and adventure play; girls' groups were interested in free play with less physical movement and challenges; inactive boys' groups were interested in relaxing and competitive play with bodily contact. However, children mentioned that busy schedules, weather, and health-related factors acted as main barriers. Lastly, children noted facilitators include setting schedules, having access to equipment and playgrounds, and holding special events. The findings provide insights into active free play-related factors for active and inactive Japanese children and also clarify the differences between Japanese and Western children. Such findings will contribute to designing interventions to increase active free play. © The Author(s) 2013.

  3. Provas da função pulmonar. Controlo de qualidade. Aspectos gerais (1a Parte

    Directory of Open Access Journals (Sweden)

    J.M. Reis Ferreira

    1999-07-01

    Full Text Available RESUMO: Os autores procuraram neste artigo sensibilizar todos os que lidam de perto com a realização dos testes da função respiratória, para a importância da qualidade e dos meios disponiveis para conseguir o seu controlo. Foram deste modo encarados os diferentes factores intervenientes na qualidade, analisandoos de acordo com os dados fornecidos fundamentalmente pela experiência. Foram assim focados, neste primeiro artigo, apenas aspectos gerais trazidos pela prática do dia a dia, a que se seguirá a publicação de novo texto em que serão, dentro do mesmo âmbito, encaradas as diferentes técnicas actualmente usadas para a avaliação da Função Respiratória.REV PORT PNEUMOL 1999; V (4: 393-404 ABSTRACT: The authors claim for the importance of the quality control in order to assure clinically useful results and a well-functioning lung function laboratory, and analyse briefly the different general factors that could be involved in the lack of quality.REV PORTPNEUMOL 1999; V (4: 393-404 Key-words: Quality control, Equipment, Calibration, Accuracity, Colaboration, Palavras-chave: Controlo de qualidade, Equipamento, Calibração, Precisão, Exactidão;Colaboração

  4. DaGO-Fun: tool for Gene Ontology-based functional analysis using term information content measures.

    Science.gov (United States)

    Mazandu, Gaston K; Mulder, Nicola J

    2013-09-25

    The use of Gene Ontology (GO) data in protein analyses have largely contributed to the improved outcomes of these analyses. Several GO semantic similarity measures have been proposed in recent years and provide tools that allow the integration of biological knowledge embedded in the GO structure into different biological analyses. There is a need for a unified tool that provides the scientific community with the opportunity to explore these different GO similarity measure approaches and their biological applications. We have developed DaGO-Fun, an online tool available at http://web.cbio.uct.ac.za/ITGOM, which incorporates many different GO similarity measures for exploring, analyzing and comparing GO terms and proteins within the context of GO. It uses GO data and UniProt proteins with their GO annotations as provided by the Gene Ontology Annotation (GOA) project to precompute GO term information content (IC), enabling rapid response to user queries. The DaGO-Fun online tool presents the advantage of integrating all the relevant IC-based GO similarity measures, including topology- and annotation-based approaches to facilitate effective exploration of these measures, thus enabling users to choose the most relevant approach for their application. Furthermore, this tool includes several biological applications related to GO semantic similarity scores, including the retrieval of genes based on their GO annotations, the clustering of functionally related genes within a set, and term enrichment analysis.

  5. A 30-month worksite-based lifestyle program to promote cardiovascular health in middle-aged bank employees: Design of the TANSNIP-PESA randomized controlled trial.

    Science.gov (United States)

    Coffeng, Jennifer K; van der Ploeg, Hidde P; Castellano, José M; Fernández-Alvira, Juan M; Ibáñez, Borja; García-Lunar, Inés; van der Beek, Allard J; Fernández-Ortiz, Antonio; Mocoroa, Agustín; García-Leal, Laura; Cárdenas, Evelyn; Rojas, Carolina; Martínez-Castro, María I; Santiago-Sacristán, Silvia; Fernández-Gallardo, Miriam; Mendiguren, José M; Bansilal, Sameer; van Mechelen, Willem; Fuster, Valentín

    2017-02-01

    Cardiovascular disease (CVD) is the leading cause of death worldwide. With atherosclerosis as the underlying cause for many CVD events, prevention or reduction of subclinical atherosclerotic plaque burden (SAPB) through a healthier lifestyle may have substantial public health benefits. The objective was to describe the protocol of a randomized controlled trial investigating the effectiveness of a 30-month worksite-based lifestyle program aimed to promote cardiovascular health in participants having a high or a low degree of SAPB compared with standard care. We will conduct a randomized controlled trial including middle-aged bank employees from the Progression of Early Subclinical Atherosclerosis cohort, stratified by SAPB (high SAPB n=260, low SAPB n=590). Within each stratum, participants will be randomized 1:1 to receive a lifestyle program or standard care. The program consists of 3 elements: (a) 12 personalized lifestyle counseling sessions using Motivational Interviewing over a 30-month period, (b) a wrist-worn physical activity tracker, and (c) a sit-stand workstation. Primary outcome measure is a composite score of blood pressure, physical activity, sedentary time, body weight, diet, and smoking (ie, adapted Fuster-BEWAT score) measured at baseline and at 1-, 2-, and 3-year follow-up. The study will provide insights into the effectiveness of a 30-month worksite-based lifestyle program to promote cardiovascular health compared with standard care in participants with a high or low degree of SAPB. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  6. Elections of members to the Governing Board of the Pension Fund

    CERN Multimedia

    2005-01-01

    This year, one member and two alternates are to be elected. The candidate who obtains the most votes will be elected member and the other candidates will be their alternates. These elections will take place following the timetable given below: Monday 21 November 2005 Voting closes at 12:00. Counting of votes from 14:30. Tuesday 22 November 2005 Forwarding of results to the Communications Section for publication in the Bulletin of 28 November. CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH PENSION FUND ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate: Name: MARTEL First Name: Pedro I arrived at CERN as a Staff member in 1995, and have been working with Engineering Databases since then. I am also personally interested in (macro and micro) economic issues. As a member of the Staff Association's Executive Commission in charge ...

  7. Elections of members to the Governing Board of the Pensions Fund

    CERN Document Server

    2004-01-01

    This year, two members and two alternates are to be elected. The candidates who obtain most votes will be elected members and the other candidates will be their alternates. Timetable (extract) : Monday 22 November 2004 Voting closes at 12 hrs. Counting of votes from 14.30 hrs. Tuesday 23 November 2004 Forwarding of results to the Communications Section for publication in the Bulletin of 29 November. ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate: Name : CHIAVERI First Name : Enrico I have been a CERN staff member since 1973 and have always been interested in our working conditions. As a member of the Executive Committee of the Staff Association I participated from 1980 to 1984 in the Working G...

  8. Elections of members to the Governing Board of the Pensions Fund

    CERN Document Server

    2004-01-01

    This year, two members and two alternates are to be elected. The candidates who obtain most votes will be elected members and the other candidates will be their alternates. New timetable (extract) : Monday 6 December 2004 Publication of the candidates' publicity and the statement from all the candidates in the Bulletin. Monday 3 January 2005 Distribution of the new ballot papers at CERN. Monday 10 January 2005 Second publication of the candidates' publicity and the statement from all the candidates in the Bulletin. Monday 31 January 2005 Voting closes at 12 hrs. Counting of votes from 14.30 hrs. Tuesday 1st February 2005 Forwarding of results to the Communications Section for publication in the Bulletin of 7 February. Statement from the Candidates for Election to the Governing Board of the Pension Fund The composition of the Governing Board of the CERN Pension Fund is as follows. two members appointed by the CERN council and two alternates two members appointed by the DG of C...

  9. Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members.

    Science.gov (United States)

    Zhao, Yue; Wu, Junnan; Zhang, Mingchao; Zhou, Minlin; Xu, Feng; Zhu, Xiaodong; Zhou, Xianguang; Lang, Yue; Yang, Fan; Yun, Shifeng; Shi, Shaolin; Liu, Zhihong

    2017-08-01

    Angiotensin II (AngII) is capable of inducing calcium/calcineurin signaling and podocyte injury; however, the precise underlying mechanism is not well understood. Because we have previously demonstrated that microRNA-30s (miR-30s) inhibit calcium/calcineurin signaling in podocytes, we hypothesize that AngII may induce podocyte injury by downregulating miR-30s and thereby activating calcium/calcineurin signaling. To test this hypothesis, we used an AngII-induced podocyte injury mouse model. The mice were treated with AngII via infusion for 28 days, which resulted in hypertension, albuminuria, and glomerular damage. AngII treatment also resulted in a significant reduction of miR-30s and upregulation of calcium/calcineurin signaling components, including TRPC6, PPP3CA, PPP3CB, PPP3R1, and NFATC3, which are the known targets of miR-30s in podocytes. The delivery of miR-30a-expressing lentivirus to the podocytes on day 14 of the infusion ameliorated the AngII-induced podocyte and glomerular injury and attenuated the upregulation of the calcium/calcineurin signaling components. Similarly, treatment with losartan, which is an AngII receptor blocker, also prevented AngII-induced podocyte injury and calcium/calcineurin signaling activation. Notably, losartan was found to sustain miR-30 levels during AngII treatment both in vivo and in vitro. In conclusion, the effect of AngII on podocytes is in part mediated by miR-30s through calcium/calcineurin signaling, a novel mechanism underlying AngII-induced podocyte injury. • AngII infusion resulted in downregulation of miR-30s in podocytes. • Exogenous miR-30a delivery mitigated the glomerular and podocyte injuries induced by AngII. • Both miR-30a and losartan prevented AngII-induced activation of calcium-calcineurin signaling.

  10. Skill improvement among coalition members in the California Healthy Cities and Communities Program.

    Science.gov (United States)

    Kegler, Michelle C; Norton, Barbara L; Aronson, Robert

    2007-06-01

    Community-driven, collaborative approaches to health promotion have the potential to enhance skills among community members and, in turn, increase community capacity. This study uses data from an evaluation of the California Healthy Cities and Communities (CHCC) Program to examine whether, and how, community problem-solving and collaboration skills are improved among coalition members and local coordinators in 20 participating communities. Methods include semi-structured interviews with coordinators and mailed surveys with coalition members (n=330 in planning phase and n=243 in implementation phase). The largest number of coordinators reported skill improvement in defining health broadly and assessing needs and assets. Similarly, coalition members reported greatest skill improvement for defining health broadly, assessing needs and assets and setting priorities and developing action plans. Modest correlations were observed between number of roles played in the local healthy cities and communities project and each skill area assessed. Time committed to the local CHCC coalition and its activities was not meaningfully correlated with any of the skills. Types of skill-building opportunities may be more important than number of hours devoted to meetings and activities in strengthening community problem-solving and collaboration skills among coalition members.

  11. Metabolic Syndrome in Korean Cancer Survivors and Family Members: A Study in a Health Promotion Center.

    Science.gov (United States)

    Shin, Jin Young; Choi, Yoon Ho; Song, Yun Mi

    2015-01-01

    This cross-sectional study evaluated the risk of metabolic syndrome (MetS) in cancer survivors and family members. Subjects were 48,934 adults (24,786 men, 24,148 women) aged ≥40yr who receive a routine health examination at 1 hospital from January 2010 to December 2012. There were 2468 cancer survivors, 18,211 with cancer patients in the family, and 28,255 noncancer subjects, who never experienced cancer and whose family members either. Associations between MetS and cancer experience were assessed using multiple logistic regression analysis. The odds ratio (OR) of MetS in female cancer survivors was significantly higher than noncancer subjects after adjusting for age, smoking, physical activity, and alcohol intake (OR = 1.22, 95% confidence intervals: 1.02-1.47]. However, the OR of MetS for male survivors did not differ from that of noncancer subjects. Gastric cancer survivors had a lower OR of MetS than noncancer subjects (0.37, 0.27-0.50). ORs of breast cancer (1.49, 1.00-2.23) and prostate cancer survivors (1.46, 1.07-1.99) were higher than the OR of MetS for noncancer subjects. There was no difference in the OR of MetS between the family members of cancer patients and non-cancer subjects. These findings suggest that the odds of MetS for cancer survivors may differ by cancer type and by sex.

  12. Evaluation in health promotion: thoughts from inside a human research ethics committee.

    Science.gov (United States)

    Allen, Judy; Flack, Felicity

    2015-12-01

    Health promotion research, quality improvement and evaluation are all activities that raise ethical issues. In this paper, the Chair and a member of human resear ch ethics committees provide an insiders' point of view on how to demonstrate ethical conduct in health promotion research and quality improvement. Several common issues raised by health promotion research and evaluation are discussed including researcher integrity, conflicts of interest, use of information, consent and privacy.

  13. Estudo morfológico do funículo espermático em ovinos da raça Corriedale (Ovis aries, L. 1758

    Directory of Open Access Journals (Sweden)

    Roberto Carvalhal

    2000-01-01

    Full Text Available Estudamos em 40 ovinos adultos da raça Corriedale os aspectos histológicos do funículo espermático. Observamos que este se acha envolvido por uma cápsula de tecido conjuntivo fibroelástico denso, de espessura variável, pregueada em alguns pontos, e revestida por mesotélio que circunda todo o conjunto vásculo-nervoso, e projeta-se para formar o mesoducto deferente. Em posição subcapsular, verifica-se uma camada de tecido conjuntivo fibroelástico frouxo, de espessura variável, que circunda parcialmente o funículo espermático, isolando nas regiões deferencial e abdeferencial conjuntos vásculo-nervosos, responsáveis pela nutrição do epidídimo. Na região do mesoducto deferente, o tecido subcapsular acompanhado de tecido adiposo constitui a camada interna deste meso, formando a sua adventícia e abrigando vasos e nervos deferenciais. Na região abdeferencial, pequenos acúmulos de tecido adiposo são vistos de permeio aos vasos e nervos desta região. Entre as artérias, veias e nervos testiculares, bem como entre os vasos das regiões deferencial e abdeferencial, observa-se o tecido conjuntivo denso, intervascular, rico em fibras elásticas, que constitui as adventícias contínuas destes vasos. O arranjo vascular mostra que o segmento da artéria testicular, contido no funículo espermático, apresenta trajeto sinuoso. Estando envolvido pelo plexo venoso pampiniforme, formado por veias testiculares desprovidas de válvulas de calibres variados, apresentando amplas comunicações entre si. As veias responsáveis pela drenagem do epidídimo e ducto deferente estão localizadas em posição subcapsular deferencial e abdeferencial e mostram-se providas de válvulas. O trato das artérias testiculares no funículo espermático apresenta como comprimento médio, máximo e mínimo, respectivamente, 150,4 cm, 198,0 cm e 73,3 cm, à direita, e 149,6 cm, 189,2 cm e 90,0 cm, à esquerda, não existindo diferenças estatisticamente

  14. A representação da função paterna para instituições de auxílio a adolescentes em conflito com a lei

    OpenAIRE

    Silva,Ricardo Alves da; Araújo,Sandra Maria Baccara

    2013-01-01

    No presente artigo articula-se a importância da função paterna para o desenvolvimento da criança e do adolescente e como a falta dessa função faz o jovem buscar alguém que a exerça. Muitas vezes, durante essa busca, os adolescentes cometem atos infracionais que os levam a entrar em conflito com a lei e, consequentemente, entrar em contato com os atores da justiça, que podem representar os limites que esses adolescentes procuraram. A metodologia adotada é a epistemologia qualitativa, que enfoc...

  15. Science in the (CERN) Pub!

    CERN Multimedia

    2001-01-01

    The 6th Public Communication of Science and Technology network conference will end on Saturday 3 February with special performances. At 14:30 in the coffee area of restaurant no. 1 (Main Building) all participants and interested CERN members are invited to two events that will address science in an unorthodox and amusing way. Australian scientists will start with Science in the Pub, a fun discussion of topical science in an Australian pub ambiance (free Foster's beer served). Cabaret Pasteur, a French sample of entertainment with a scientific touch will follow.

  16. The effect of an anger management program for family members of patients with alcohol use disorders.

    Science.gov (United States)

    Son, Ju-Young; Choi, Yun-Jung

    2010-02-01

    This study was aimed to test the structured anger management nursing program for the family members of patients with alcohol use disorders (AUDs). Families with the AUDs suffer from the dysfunctional family dynamic caused by the patients' deteriorative disease processes of alcohol dependence. Family members of AUDs feel bitter and angry about the uncontrolled behaviors and relapses of the patients in spite of great effort for a long time. This chronic anger threatens the optimal function of the family as well as obstructs the family to help the patients who are suffering from AUDs. Sixty three subjects were participated who were referred from community mental health centers, alcohol consultation centers, and an alcohol hospital in Korea. Pre-post scores of the Korean Anger Expression Inventory were used to test the program. An anger management program was developed and implemented to promote anger expression and anger management for the family members of the patients with AUDs. The total anger expression score of the experimental group was significantly more reduced as compared with that of the control group. Subjects in the experimental group reported after the program that they felt more comfortable and their life was changed in a better way. The anger management program was effective to promote anger expression and anger management for family members of AUDs. Nurses need to include family members in their nursing process as well as to care of patients with AUDs to maximize nursing outcome and patient satisfaction. 2010 Elsevier Inc. All rights reserved.

  17. Teaching physical education by the perspective of psychomotor development and health promotion

    Directory of Open Access Journals (Sweden)

    Hana Dvořáková

    2015-07-01

    Full Text Available BACKGROUND: Teaching physical education should refl ect changes in education and changes in the concept of physical education as a part of health education in the broad sense, it means physical, mental and social health. In addition to provable positive benefi ts of physical activity on health, it is generally considered diffi cult to demonstrate the infl uence of physical education on diff erent ways of life. Results of studies indicate failure of education in physical education in practical and information process. Perceived physical competence, fun, the activity and monitoring individual progress are considered as positive correlates of the infl uence of physical education on lifestyle (Dobrý, 2007.OBJECTIVE: The aims of this paper is to point out that psychomotor activities could bring positive changes in teaching physical education.METHODS: This paper examined various studies, personal experiencies from abroad and practice.RESULTS: Physical activities and games in pedagogical concept of ps. development are intentionally aimed at the physical and motoric development in connection with mental processes and social relations, promote personal knowledge and personal development, self-activity and creativity, are fun and lead to the acquisition of key competencies. Using psychomotor teaching methods could support this impact of psychomotor activities and help to make positive changes in physical education.CONCLUSIONS: Psychomotor activities can help the modern concept of physical education if in addition to practical activities there is also included theoretical and didactic knowledge that increase the possibility of rational and intentional use of these activities.

  18. Adoption of an evidence-based colorectal cancer screening promotion program by community organizations serving Filipino Americans

    Science.gov (United States)

    2014-01-01

    Background Filipino Americans have low rates of colorectal cancer (CRC) screening and high CRC mortality. To reduce this disparity, we conducted a dissemination trial in which we offered two levels of technical assistance to community organizations to disseminate an evidence-based CRC screening promotion program among their Filipino American members. This report describes the recruitment of organizations and adoption – the proportion and representativeness of organizations that decided to implement the program. Methods During the recruitment phase, we completed organizational assessments with 44 community-based organizations (previous partners in research, organizations that were referred to us, or new organizations) to assess their eligibility to participate (having ≥ 150 Filipino American members age 50+). We compared organizational characteristics of organizations that did and did not adopt our CRC screening promotion program. Results Twenty two of the 44 community organizations that completed the assessment adopted the CRC screening promotion program (50%). Adoption was highest among organizations that had previously partnered with us (11/14 = 79%) and among organizations that were referred to us by community partners (5/10 = 50%) and lowest among new organizations (6/20 = 30%). Few organizational differences were found between adopters and non-adopters. Conclusions The high rate of adoption among organizations that were referred by community partners or had partnered with us in the past underscores the importance of community resources, community-academic relationships, and partnership in the dissemination process. However, the moderate rate of adoption among new organizations and the demands of completing documentation and assessments in our trial to advance dissemination research raise questions regarding the generalizability of study findings. PMID:24618267

  19. Offers for our members

    CERN Multimedia

    Staff Association

    2013-01-01

    The Courir shops propose the following offer: 15% discount on all articles (not on sales) in the Courir shops (Val Thoiry, Annemasse and Neydens) and 5% discount on sales upon presentation of your Staff Association membership card and an identity card before payment. Summer is here, enjoy our offers for the aquatic parcs! Walibi : Tickets "Zone terrestre": 21 € instead of 26 €. Access to Aqualibi: 5 € instead of 8 € on presentation of your SA member ticket. Free for children (3-11 years old) before 12 h 00. Free for children under 3, with limited access to the attractions. Car park free. * * * * * Aquaparc : Day ticket: – Children: 30 CHF instead of 39 CHF – Adults : 36 CHF instead of 49 CHF Bonus! Free for children under 5.

  20. Results of Questionnaire for the member of JHPS concerning the criticality accident at Tokai

    International Nuclear Information System (INIS)

    2000-01-01

    During the investigation of the criticality accident at Tokai occurring on Sep. 30, 1999, the project team in Japan Health Physics Society (JHPS) carried out a questionnaire for the member on the accident and this paper summarized its results. The effective answer was obtained in 36% of members. Major questions (and frequent answers) were: media of information obtained (internet 33%, TV and radio 22%, and newspaper 19%); concerning actions done by Japanese and local governments, the recommendation on Sep. 30 at 15:00 of evacuation for people living in the area within the radius of 350 m (necessary 92%), timing of its release on Oct. 2 at 18:30 (appropriate 41% and too late 36%) and its information to the people (more information needed 60%) and the recommendation on Sep. 30 at 22:30 of in-door refuge within 10 km radius (unnecessary 43% and necessary 41%), timing of its release on Oct. 1 at 16:40 (too late 49%) and its information to the people (more information needed 63%); and safety declaration for food etc. on Oct. 2 at 18:30 (necessary 92%). Based on above results and free description on the questionnaire, JHPS considered the necessity of described systems of JHPS for emergency.(K.H.)

  1. Studies on the tumor initiation/promotion potential of six middle distillates (MDs) in mouse skin.

    Science.gov (United States)

    Jungen, H; Mellert, W; Wenzel-Hartung, R

    1995-08-01

    Six middle distillates (MDs) were tested for tumor initiating/promoting activity after application to the skin of 30 male CD-1 (ICR) BR mice per group. As the control, 7,12-dimethylbenz[a]-anthracene (DMBA) was used for initiation followed by 12-O-tetradecanoylphorbol-13-acetate (TPA) for promotion. For assessing the tumor-initiating activity, 50 microliters of neat MDs was administered for 5 days with subsequent TPA promotion. In the promotion bioassay, after DMBA initiation 50 microliters of the neat MDs was administered twice weekly until Week 28. For the examination of complete carcinogenic activity, one MD was given without DMBA initiation. Hyperkeratosis, hyperplasia, and dermal inflammation, occurring during the initiation with the MDs, were completely reversible during the 2-week treatment-free period after initiation. Similar skin findings were observed during promotion with the MDs. Regarding the number of affected animals and the severity of the response, TPA was more irritating than the MDs. The initiation study revealed skin tumors for the DMBA/TPA control (30/30), MD 57,389 (14/30), MD 57,396 (5/30), MD 57,383 (4/30) and MD 57,324 (2/30). The promotion study revealed tumor induction by MDs 57,389 (9/30), 57,324 (1/30), 57,393 (1/30), and 57,396 (1/30). Two of 30 animals treated with MD 57,389 developed tumors without DMBA initiation thus indicating that it also is a complete carcinogen. MD 57,399 caused neither initiating nor promoting effects. The tumors observed were diagnosed histopathologically predominantly as squamous cell papillomas.(ABSTRACT TRUNCATED AT 250 WORDS)

  2. The strategy of a european health policy of the who member states

    International Nuclear Information System (INIS)

    Johansen, K.S.

    1992-01-01

    The policy of Health for All is a challenge by the World Health Organization to its Member States to ensure each citizen an e conomically and socially productive life . The Regional Office for Europe created an expanded version of this policy, known as European Health for All, which urged each Member State to alter its policies to achieve the targets set out therein. This policy calls for more equity and social justice in health, for prevention of disease and promoting health and quality of life and for improving the human environment. One of the most important items is the call for delivering quality of care for everyone, by using a clear system for measuring the outcomes of care. Quality of care must apply equally to all parts of the cycle, from health promotion, prevention, diagnosis, treatment and rehabilitation. For quality development and assurance in the area of imaging and the role of dosimetry, the Health for All set a goal of ensuring optimal outcome from available resources. To reach this goal, it is necessary to set standards for guiding health outcome indicators in order to systematically assess health technologies

  3. Convergence of the Policies for Promoting Total Quality Management in the Public Administrations of Balkan States – European Union Member States

    Directory of Open Access Journals (Sweden)

    Ani MATEI

    2011-03-01

    Full Text Available In the past three decades, total quality management (TQM has been appreciated as “fundamental modality in view to improve the activity in the public and private sectors” (Boyne and Walker, 2002, p. 1. For the time being, in public administrations, we witness an extension of the policies for promoting TQM, although the experiences have not always been positive.The European Administrative Space (EAS incorporates TQM, in different manners at national level, taking into consideration its recognised impact on the efficiency of public administration, one of EAS fundamental principles (Zurga, 2008, pp. 39-49. In the context of analysing EAS evolution, the administrative convergence will also comprise the convergence of TQM policies. In fact, the field literature (Hackman, Wageman, 1995 reveals, in the context of national TQM policy-making, the concepts of ”Convergent validity” and ”Discriminant validity”, reflecting ”the degree to which the version of TQM promulgated by the founders and observed in organizational practice share a common set of assumptions and prescriptions” (Hackman, Wageman, 1995, pp. 318-319.By a comparative analysis on TQM policies in the national public administrations of Balkan states, EU Member States: Greece, Cyprus, Slovenia, Bulgaria and Romania, the current paper aims to reveal the level of their convergence as well as the theoretical consistency of the conceptual and practical framework for TQM assertion.The comparative analysis will be based on a comprehensive vision on TQM, provided by Dean and Bowen (1994, Boyne and Walker (2002, namely its approach should be characterised on own principles, practices and techniques, grouped on customer focus, continuous improvement and team work (Boyne and Walker, 2002, pp. 4-5.The tradition on promoting TQM in public administration in the above-mentioned states is relatively recent: since 1990s – Cyprus, since 1995 – Greece and Slovenia, since 2000 – Bulgaria and

  4. A Non-Member Spouse's Entitlement To The Member's Pension Interest

    Directory of Open Access Journals (Sweden)

    Motseotsile Clement Marumoagae

    2014-12-01

    Full Text Available It is important that married couples seek legal advice with regard to the assets falling within their joint estate, more particularly their retirement benefits. This article reflects on the entitlement (if any of non-member spouses to their spouses' retirement fund benefits. Pension benefits can be due before, during or after divorce, and parties to the marriage should be aware of their rights with regard to the accruing pension benefits of their spouses. While it is settled law that non-member spouses are entitled to receive a portion of their member spouses' pension benefits (known as "pension interest" immediately on divorce, it is not particularly clear whether non-member spouses are also entitled to receive the same before or sometime after divorce. In this article I provide a contextual understanding of the entitlements (if any which spouses or former spouses of members of pension funds have on such member spouses' retirement benefits. Furthermore, it shown in this article that various divisions of South African High Courts have been inconsistent in how they have approached the issue of the pension interest between divorcing spouses or divorced ex-spouses.

  5. Effectiveness of Cognitive-Functional (Cog-Fun) occupational therapy intervention for young children with attention deficit hyperactivity disorder: a controlled study.

    Science.gov (United States)

    Maeir, Adina; Fisher, Orit; Bar-Ilan, Ruthie Traub; Boas, Naomi; Berger, Itai; Landau, Yael E

    2014-01-01

    The purpose of this study was to examine the effectiveness of the Cognitive-Functional (Cog-Fun) intervention for young children with attention deficit hyperactivity disorder (ADHD). Nineteen children ages 5-7 yr diagnosed with ADHD were allocated to treatment and wait-list control groups. After the 12-wk intervention, the control group was crossed over to treatment. Follow-up was conducted 3 mo after treatment. Outcome measures included the Behavior Rating Inventory of Executive Function and the Canadian Occupational Performance Measure. Before crossover, significant differences were found between groups in change scores on the outcome measures. After crossover, no significant differences were found in treatment effects, and significant moderate to large treatment effects were found for both COPM and BRIEF scores. Treatment gains were maintained at follow-up. The study supports the effectiveness of the Cog-Fun intervention in improving occupational performance and executive functions in daily life for young children with ADHD. Copyright © 2014 by the American Occupational Therapy Association, Inc.

  6. Tips for Constructing a Promotion and Tenure Dossier that Documents Engaged Scholarship Endeavors

    Science.gov (United States)

    Franz, Nancy K.

    2011-01-01

    The growth of the community engagement movement in higher education over the past 2 decades has resulted in more faculty member interest and practice in engaged scholarship. As more institutions value this work, faculty members are looking for ways to enhance the effectiveness of their engaged scholarship dossiers for promotion and tenure. This…

  7. On the way to fun an emotion-based approach to successful game design

    CERN Document Server

    Dillon, Roberto

    2010-01-01

    On the Way to Fun outlines a fine framework linking human emotions and instincts to successful game design, blending a theoretical framework with keys to analyzing game play. The framework is then applied to both successful and unsuccessful games to make for a fine survey for any who want to properly design and develop ideas to maximum benefit.-Midwest Book Review, January 2011I love the '6-11 Framework'. It's a brilliant analysis. Wish I'd thought of it. Emotion is essential to establishing a deep connection with games. So many games lack it, and this book shows the way. The analyses of retro

  8. Advancing Engaged Scholarship in Promotion and Tenure: A Roadmap and Call for Reform

    Science.gov (United States)

    O'Meara, KerryAnn; Eatman, Timothy; Petersen, Saul

    2015-01-01

    Despite the precipitous increase in nontenure-track faculty appointments, the promotion and tenure process continues to operate as a central "motivational and cultural force in the academic lives" of many faculty members. As a part of larger reward systems, the promotion and tenure process reflects institutional values, aspirations,…

  9. O conceito de função e sua linguagem para os professores de matemática e de ciências

    Directory of Open Access Journals (Sweden)

    Edna Maura Zuffi

    2002-01-01

    Full Text Available Neste artigo, apresentamos alguns dos resultados obtidos com a observação da prática pedagógica de três professores de Matemática do Ensino Médio, ao usarem a linguagem matemática no ensino de "funções". A partir de uma análise qualitativa dos dados, são propostas algumas categorias representativas das concepções geradas na sala de aula com o tema em questão, a partir das formas de expressão efetivamente articuladas pelos professores, junto aos seus alunos. Algumas considerações também são propostas sobre a relação entre estas concepções e o uso de uma linguagem específica para se tratar as "funções" no ensino de Química e Física.

  10. 5 CFR 3201.106 - Employment of family members outside the Corporation.

    Science.gov (United States)

    2010-01-01

    ... Employment of family members outside the Corporation. (a) Disqualification of employees. An employee shall... relationships. A covered employee shall make a written report to an agency designee within 30 days of the... relationship; or (3) A firm or business which, to the employee's knowledge, is seeking a business or...

  11. FUn: a framework for interactive visualizations of large, high-dimensional datasets on the web.

    Science.gov (United States)

    Probst, Daniel; Reymond, Jean-Louis

    2018-04-15

    During the past decade, big data have become a major tool in scientific endeavors. Although statistical methods and algorithms are well-suited for analyzing and summarizing enormous amounts of data, the results do not allow for a visual inspection of the entire data. Current scientific software, including R packages and Python libraries such as ggplot2, matplotlib and plot.ly, do not support interactive visualizations of datasets exceeding 100 000 data points on the web. Other solutions enable the web-based visualization of big data only through data reduction or statistical representations. However, recent hardware developments, especially advancements in graphical processing units, allow for the rendering of millions of data points on a wide range of consumer hardware such as laptops, tablets and mobile phones. Similar to the challenges and opportunities brought to virtually every scientific field by big data, both the visualization of and interaction with copious amounts of data are both demanding and hold great promise. Here we present FUn, a framework consisting of a client (Faerun) and server (Underdark) module, facilitating the creation of web-based, interactive 3D visualizations of large datasets, enabling record level visual inspection. We also introduce a reference implementation providing access to SureChEMBL, a database containing patent information on more than 17 million chemical compounds. The source code and the most recent builds of Faerun and Underdark, Lore.js and the data preprocessing toolchain used in the reference implementation, are available on the project website (http://doc.gdb.tools/fun/). daniel.probst@dcb.unibe.ch or jean-louis.reymond@dcb.unibe.ch.

  12. Soil science is way more fun than a proper job (Philippe Duchaufour Medal Lecture)

    Science.gov (United States)

    Smith, Pete

    2017-04-01

    Having now worked in soil science and climate change for over 20 years, I find myself giving one of the "old man / old woman" lectures at the EGU2017. You probably get picked to do this when your peers think that you are about to die soon, so I had better make the most of my time left! We are very fortunate to have a career in science, and to belong to the soils, and the wider, biogeosciences communities. If ever you get fed up with your teaching load, with your experiment that won't work, your model that you can't get running, or your paper that reviewers do not realise for the gem that you know it is, remember that we could be doing a 9 to 5 job, stuck in an office, with no opportunities to meet, talk and have fun with others from around the world with whom we share the same passion. I hope you enjoy your research careers and the time you spend with your work friends as much as I have. In this presentation I will reflect on how much I have learned about soils, climate, and the politics of how things get done over the past 20 years, and I will pick out some changes in our understanding of soils, and their role in the world as I go. I will draw on examples not only from my own work, but those of others, and will reflect on the some of the fun I have had while doing this "job".

  13. Cyclic adenosine 3',5'-monophosphate (cAMP) enhances cAMP-responsive element binding (CREB) protein phosphorylation and phospho-CREB interaction with the mouse steroidogenic acute regulatory protein gene promoter.

    Science.gov (United States)

    Clem, Brian F; Hudson, Elizabeth A; Clark, Barbara J

    2005-03-01

    Steroidogenic acute regulatory protein (StAR) transcription is regulated through cAMP-protein kinase A-dependent mechanisms that involve multiple transcription factors including the cAMP-responsive element binding protein (CREB) family members. Classically, binding of phosphorylated CREB to cis-acting cAMP-responsive elements (5'-TGACGTCA-3') within target gene promoters leads to recruitment of the coactivator CREB binding protein (CBP). Herein we examined the extent of CREB family member phosphorylation on protein-DNA interactions and CBP recruitment with the StAR promoter. Immunoblot analysis revealed that CREB, cAMP-responsive element modulator (CREM), and activating transcription factor (ATF)-1 are expressed in MA-10 mouse Leydig tumor cells, yet only CREB and ATF-1 are phosphorylated. (Bu)2cAMP treatment of MA-10 cells increased CREB phosphorylation approximately 2.3-fold within 30 min but did not change total nuclear CREB expression levels. Using DNA-affinity chromatography, we now show that CREB and ATF-1, but not CREM, interact with the StAR promoter, and this interaction is dependent on the activator protein-1 (AP-1) cis-acting element within the cAMP-responsive region. In addition, (Bu)2cAMP-treatment increased phosphorylated CREB (P-CREB) association with the StAR promoter but did not influence total CREB interaction. In vivo chromatin immunoprecipitation assays demonstrated CREB binding to the StAR proximal promoter is independent of (Bu)2cAMP-treatment, confirming our in vitro analysis. However, (Bu)2cAMP-treatment increased P-CREB and CBP interaction with the StAR promoter, demonstrating for the first time the physical role of P-CREB:DNA interactions in CBP recruitment to the StAR proximal promoter.

  14. [The present status and attempts toward the achievement of gender equality in the JAA].

    Science.gov (United States)

    Senba, Emiko

    2013-09-01

    The proportion of female members in The Japanese Association of Anatomists (JAA) is 18% with the proportion of female members higher among the young generation (20-30 Y.O.; 34.8%, 30-40 Y.O.; 26.8%). However, the number of female members in the Board of Directors has been zero or one (0 or 6%) for many years. More than two female members are necessary on the Board to promote the diversity in the management of the JAA. The numbers of female members in other committees has shown gradual increase in recent years. A substantial increase in female faculty members including professors in each university and school will support the future development of the anatomical research field and the association. We have made the first great step by setting up the committee on promotion of gender equality in JAA in March, 2011. In the next year, JAA became a member of Japan Inter-Society Liaison Association Committee for Promoting Equal Participation of Men and Women in Science and Engineering (EPMEWSE). Our committee's activity includes holding workshops and seminars at the annual meetings to promote gender equality in the research field and to encourage mutual support and friendship, not only among women members but also among all members.

  15. Calcium-aluminum-rich inclusions with fractionation and unidentified nuclear effects (FUN CAIs): II. Heterogeneities of magnesium isotopes and 26Al in the early Solar System inferred from in situ high-precision magnesium-isotope measurements

    Science.gov (United States)

    Park, Changkun; Nagashima, Kazuhide; Krot, Alexander N.; Huss, Gary R.; Davis, Andrew M.; Bizzarro, Martin

    2017-03-01

    Calcium-aluminum-rich inclusions with isotopic mass fractionation effects and unidentified nuclear isotopic anomalies (FUN CAIs) have been studied for more than 40 years, but their origins remain enigmatic. Here we report in situ high precision measurements of aluminum-magnesium isotope systematics of FUN CAIs by secondary ion mass spectrometry (SIMS). Individual minerals were analyzed in six FUN CAIs from the oxidized CV3 carbonaceous chondrites Axtell (compact Type A CAI Axtell 2271) and Allende (Type B CAIs C1 and EK1-4-1, and forsterite-bearing Type B CAIs BG82DH8, CG-14, and TE). Most of these CAIs show evidence for excess 26Mg due to the decay of 26Al. The inferred initial 26Al/27Al ratios [(26Al/27Al)0] and the initial magnesium isotopic compositions (δ26Mg0) calculated using an exponential law with an exponent β of 0.5128 are (3.1 ± 1.6) × 10-6 and 0.60 ± 0.10‰ (Axtell 2271), (3.7 ± 1.5) × 10-6 and -0.20 ± 0.05‰ (BG82DH8), (2.2 ± 1.1) × 10-6 and -0.18 ± 0.05‰ (C1), (2.3 ± 2.4) × 10-5 and -2.23 ± 0.37‰ (EK1-4-1), (1.5 ± 1.1) × 10-5 and -0.42 ± 0.08‰ (CG-14), and (5.3 ± 0.9) × 10-5 and -0.05 ± 0.08‰ (TE) with 2σ uncertainties. We infer that FUN CAIs recorded heterogeneities of magnesium isotopes and 26Al in the CAI-forming region(s). Comparison of 26Al-26Mg systematics, stable isotope (oxygen, magnesium, calcium, and titanium) and trace element studies of FUN and non-FUN igneous CAIs indicates that there is a continuum among these CAI types. Based on these observations and evaporation experiments on CAI-like melts, we propose a generic scenario for the origin of igneous (FUN and non-FUN) CAIs: (i) condensation of isotopically normal solids in an 16O-rich gas of approximately solar composition; (ii) formation of CAI precursors by aggregation of these solids together with variable abundances of isotopically anomalous grains-possible carriers of unidentified nuclear (UN) effects; and (iii) melt evaporation of these precursors

  16. The Earth Science Women's Network (ESWN): A member-driven network approach to supporting women in the Geosciences

    Science.gov (United States)

    Hastings, M. G.; Kontak, R.; Adams, A. S.; Barnes, R. T.; Fischer, E. V.; Glessmer, M. S.; Holloway, T.; Marin-Spiotta, E.; Rodriguez, C.; Steiner, A. L.; Wiedinmyer, C.; Laursen, S. L.

    2013-12-01

    The Earth Science Women's Network (ESWN) is an organization of women geoscientists, many in the early stages of their careers. The mission of ESWN is to promote success in scientific careers by facilitating career development, community, informal mentoring and support, and professional collaborations. ESWN currently connects nearly 2000 women across the globe, and includes graduate students, postdoctoral scientists, tenure and non-tenure track faculty from diverse colleges and universities, program managers, and government, non-government and industry researchers. In 2009, ESWN received an NSF ADVANCE PAID award, with the primary goals to grow our membership to serve a wider section of the geosciences community, to design and administer career development workshops, to promote professional networking at scientific conferences, and to develop web resources to build connections, collaborations, and peer mentoring for and among women in the Earth Sciences. Now at the end of the grant, ESWN members have reported gains in a number of aspects of their personal and professional lives including: knowledge about career resources; a greater understanding of the challenges facing women in science and resources to overcome them; a sense of community and less isolation; greater confidence in their own career trajectories; professional collaborations; emotional support on a variety of issues; and greater engagement and retention in scientific careers. The new ESWN web center (www.ESWNonline.org), a major development supported by NSF ADVANCE and AGU, was created to facilitate communication and networking among our members. The web center offers a state-of-the-art social networking platform and features: 1) a public site offering information on ESWN, career resources for all early career scientists, and a 'members' spotlight' highlighting members' scientific and professional achievements; and 2) a password protected member area where users can personalize profiles, create and

  17. 'You're in FunDzaland': Pre-service teachers (reimagine audience on a creative writing course

    Directory of Open Access Journals (Sweden)

    Belinda Mendelowitz

    2016-07-01

    Full Text Available This study explores how collaborative writing for a digital platform can enable students to (re imagine audience. Although in the context of process writing peer feedback is foreground, in practice, its effectiveness is uneven. The digital revolution offers new opportunities for alternative peer feedback through collaborative writing and re-imagining self and other in the process. This study examines data from a creative writing course in which pre-service teachers wrote collaborative short stories for the FunDza digital site and individual reflective essays about the process. The study’s research questions are the following: (1 what were the affordances of this multilayered audience for engaging the students’ imaginations? (2 How did this process of (reimagining audience impact on students’ conceptions of themselves as writers? The data set comprised 16 collaboratively authored stories (published on the site and 34 individual reflective essays. Six of the latter were selected for detailed analysis. Hence, the data for this study encompass detailed analysis of two groups’ reflective essays on the process of writing their stories. These groups were selected because they exemplified contrasting collaborative, imaginative writing processes. Group 1 was familiar with the FunDza audience and context, while Group 2 struggled to imagine it. Thematic content analysis was used for analysis. Each essay was read first in relation to the entire data set, then in relation to the other reflections in the author’s group. The combination of gearing stories towards the FunDza audience and writing stories collaboratively created two sets of audiences that writers needed to hold in mind simultaneously. Analysis indicates that both audiences challenged students to make imaginative leaps into the minds of an unfamiliar audience, deepening their understanding of the writing process. It also highlights students’ mastery of writing discourses and increasing

  18. Teaching and Learning Coastal Processes through Research in a Non-Lab Science Course and Having Fun at the Same Time

    Science.gov (United States)

    Thissen, J.

    2014-12-01

    At Nassau Community College students are required to take one lab science and one non-lab science. These two science courses will probably be the only sciences courses they'll take in their college career. What are they looking for in a science course? "Is it easy?" "Will we have fun?" I can try for "fun" but "easy" and "science" seem to be oxymorons. I've found that they don't notice the difficulty when they're having fun. With this is mind I set out to create a course that would fulfill this requirement but also challenge them to learn science through hands-on, real-life, placed based activities and projects. Beaches and Coasts is essentially a coastal processes course that requires a full term research project along with other hands-on activities. We live on an island (Long Island, NY). The state of our shoreline impacts all of us - something we saw during Superstorm Sandy. Long Island's shorelines vary tremendously. Our north shore is glacially controlled and irregular with many harbors and bays; our south shore is an Atlantic Ocean coastline with many barrier islands and lagoons that contain many inlets and marshes. Many municipalities have small natural beaches along this coastline. For their project students choose a shoreline, with input from the instructor, and take "ownership" of it for at least one moon cycle. They collect data on tides, currents, waves, offshore sediment transport and anthropogenic structures and then study the impact of these factors on their section of shoreline. They also collect sediment from their beach to analyze later in the lab. They are given a rubric with the specific requirements and then make a PowerPoint presentation that includes all their data, charts and graphs as well as their photos that they took while doing their research. Students love doing this project. They can't believe they get credits for going to the beach - something they do anyway (the "fun" factor). They all say that they'll never go to the beach the same

  19. Members of the Agency

    International Nuclear Information System (INIS)

    2007-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.63) is Palau which deposited its Instrument of Acceptance of the Statute on 2 March 2007. The Attachment hereto shows the dates on which the present 144 Member States became Members [fr

  20. Members of the Agency

    International Nuclear Information System (INIS)

    2007-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.63) is Palau which deposited its Instrument of Acceptance of the Statute on 2 March 2007. The Attachment hereto shows the dates on which the present 144 Member States became Members [es

  1. Employment Status of the Members of Tehran Deaf Community

    Directory of Open Access Journals (Sweden)

    Shahrooz nemati

    2011-09-01

    Full Text Available Background and Aim: Regarding the importance of employment in social and emotional status of individuals, it would be important for the deaf. The purpose of the present study was to assess the employment status of the members of Tehran deaf community.Methods: This descriptive study was performed on all members of Tehran deaf community. A researchers-made questionnaire which had three parts (demographic information, employment status of the deaf members and their attitudes regarding employment was used in this study. The obtained data were analyzed using descriptive methods.Results: Majority of deaf community members were adult (ages ranging between 18 and 30. Sixty-eight of them (52.5% were female and 53 (47.5% were male, from our participants, 56.2% were unemployed and 43.8% were employed. Main problems were: having no access to facilities regarding their disability (14.5%, communication problems (9.4%, lower salaries because of their disability (12.4%, being far from the working place (15.4%, disproportion of working environment to their disability (11.4%, maltreatment of their coworkers (13.2%, maltreatment of their employer (12.5% and discrimination because of their disability (11.2%, the attitudes of the deaf members were positive regarding the employment in all areas: 90% of them considered it as an essential part of life versus 10% of them mentioned not very important issue.Conclusion: Our findings showed that most of the deaf were supported by their family members, but not by the social facilities or their past education. The social policies should be reformed to support employment of the deaf.

  2. CNS members promoting nuclear energy in public debate - an example from Quebec

    International Nuclear Information System (INIS)

    Franta, J.; Sabourin, G.; Saint-Denis, M.

    2006-01-01

    For approximately two years, several members of the Quebec branch of the Canadian Nuclear Society have publicly expressed their views in favour of nuclear energy in Quebec. This paper summarizes their participation in the BAPE public hearings on the environment ('Bureau d'Audience Publique sur l'Environnement'), in the hearings of a Quebec Parliamentary Commission on economy and labour, and in the United Nations Conference on Climate Change in December 2005 in Montreal. The focus is mainly on a debate around the possible refurbishment of the Gentilly-2 nuclear power plant, the only operating nuclear plant in Quebec. Antinuclear groups are well organized and their message is transmitted loudly to the public by the mainstream media. Industry professionals must therefore express themselves publicly to counterbalance this biased message. In conclusion, we see a need for the formation of a coalition of all who support nuclear power in Quebec to support the refurbishment of Gentilly-2. (author)

  3. CNS members promoting nuclear energy in public debate - an example from Quebec

    Energy Technology Data Exchange (ETDEWEB)

    Franta, J.; Sabourin, G.; Saint-Denis, M. [Atomic Energy of Canada Limited, Montreal, Quebec (Canada)

    2006-07-01

    For approximately two years, several members of the Quebec branch of the Canadian Nuclear Society have publicly expressed their views in favour of nuclear energy in Quebec. This paper summarizes their participation in the BAPE public hearings on the environment ('Bureau d'Audience Publique sur l'Environnement'), in the hearings of a Quebec Parliamentary Commission on economy and labour, and in the United Nations Conference on Climate Change in December 2005 in Montreal. The focus is mainly on a debate around the possible refurbishment of the Gentilly-2 nuclear power plant, the only operating nuclear plant in Quebec. Antinuclear groups are well organized and their message is transmitted loudly to the public by the mainstream media. Industry professionals must therefore express themselves publicly to counterbalance this biased message. In conclusion, we see a need for the formation of a coalition of all who support nuclear power in Quebec to support the refurbishment of Gentilly-2. (author)

  4. Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.

    Science.gov (United States)

    Meier, Daniel; Schindler, Detlev

    2011-01-01

    The Fanconi anemia (FA) gene family is a recent addition to the complex network of proteins that respond to and repair certain types of DNA damage in the human genome. Since little is known about the regulation of this novel group of genes at the DNA level, we characterized the promoters of the eight genes (FANCA, B, C, E, F, G, L and M) that compose the FA core complex. The promoters of these genes show the characteristic attributes of housekeeping genes, such as a high GC content and CpG islands, a lack of TATA boxes and a low conservation. The promoters functioned in a monodirectional way and were, in their most active regions, comparable in strength to the SV40 promoter in our reporter plasmids. They were also marked by a distinctive transcriptional start site (TSS). In the 5' region of each promoter, we identified a region that was able to negatively regulate the promoter activity in HeLa and HEK 293 cells in isolation. The central and 3' regions of the promoter sequences harbor binding sites for several common and rare transcription factors, including STAT, SMAD, E2F, AP1 and YY1, which indicates that there may be cross-connections to several established regulatory pathways. Electrophoretic mobility shift assays and siRNA experiments confirmed the shared regulatory responses between the prominent members of the TGF-β and JAK/STAT pathways and members of the FA core complex. Although the promoters are not well conserved, they share region and sequence specific regulatory motifs and transcription factor binding sites (TBFs), and we identified a bi-partite nature to these promoters. These results support a hypothesis based on the co-evolution of the FA core complex genes that was expanded to include their promoters.

  5. Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.

    Directory of Open Access Journals (Sweden)

    Daniel Meier

    Full Text Available The Fanconi anemia (FA gene family is a recent addition to the complex network of proteins that respond to and repair certain types of DNA damage in the human genome. Since little is known about the regulation of this novel group of genes at the DNA level, we characterized the promoters of the eight genes (FANCA, B, C, E, F, G, L and M that compose the FA core complex. The promoters of these genes show the characteristic attributes of housekeeping genes, such as a high GC content and CpG islands, a lack of TATA boxes and a low conservation. The promoters functioned in a monodirectional way and were, in their most active regions, comparable in strength to the SV40 promoter in our reporter plasmids. They were also marked by a distinctive transcriptional start site (TSS. In the 5' region of each promoter, we identified a region that was able to negatively regulate the promoter activity in HeLa and HEK 293 cells in isolation. The central and 3' regions of the promoter sequences harbor binding sites for several common and rare transcription factors, including STAT, SMAD, E2F, AP1 and YY1, which indicates that there may be cross-connections to several established regulatory pathways. Electrophoretic mobility shift assays and siRNA experiments confirmed the shared regulatory responses between the prominent members of the TGF-β and JAK/STAT pathways and members of the FA core complex. Although the promoters are not well conserved, they share region and sequence specific regulatory motifs and transcription factor binding sites (TBFs, and we identified a bi-partite nature to these promoters. These results support a hypothesis based on the co-evolution of the FA core complex genes that was expanded to include their promoters.

  6. 21st Century Professional Skill Training Programs for Faculty Members--A Comparative Study between Virginia Tech University, American University & King Saud University

    Science.gov (United States)

    Al-Majed, Asma; Al-Kathiri, Fatima; Al-Ajmi, Sara; Al-Hamlan, Suad

    2017-01-01

    The 21st century faculty member is expected to teach, engage the learner, absorb new discoveries and rely on different knowledge in the execution of duties. This calls for up-to-date skills for instruction, assessment, and identification of opportunities by faculty members to promote learning. This paper investigates the prospects of promoting…

  7. Development of Phanan Pandanus Handicraft Design for the Furniture Industry in Promotion of Creative-Based Economy

    Directory of Open Access Journals (Sweden)

    Payomrat Ruangrit

    2015-11-01

    Full Text Available This research study is a qualitative research which aims to (1 study the background of Phanan pandanus weaving handicraft, (2 study the problems encountered in development of Phanan pandanus weaving handicraft for the furniture industry, and (3 determine appropriate ways to develop suitable pandanus handicraft designs to promote the creative economy. The target area of this research was composed of three Thai provinces; Trang, Krabi and Satun. The research methods were study of books and printed matters, observation, interviews, group discussions and a workshop. The research findings revealed that the background and current status of Phanan pandanus weaving in each target group was similarly initiated as an ancestral legacy. Learning skill was acquired through observation without any particular textbooks. The learning activity was first started with small groups, which were extended into large groups with 20-30 members. The average age of group members is 40 years and older, with educational levels between Prathom 6 (upper primary to Mathayom 6 (upper secondary. The products made by each group are similar. In terms of the marketplace, each group aims at the domestic market. Each member earns approximately 2,500-6,000 baht per month. In terms of the problems of Phanan pandanus weaving, handicraft production mainly suffers from a lack of designers, lack of support from the government sector, unaffordable costs of hiring designers, lack of creativity in producing new products and inability to produce large quantities of products due to time consumption. According to the research findings, there are 3 guideline areas for development of Phanan pandanus handicraft design for the furniture industry in promotion of creative-based economy: (1 Guidelines for development of pandanus handicraft design; (2 Guidelines for management; (3 Guidelines for the incorporation of other equipment and materials.

  8. Gossip Versus Punishment: The Efficiency of Reputation to Promote and Maintain Cooperation.

    Science.gov (United States)

    Wu, Junhui; Balliet, Daniel; Van Lange, Paul A M

    2016-04-04

    Prior theory suggests that reputation spreading (e.g., gossip) and punishment are two key mechanisms to promote cooperation in groups, but no behavioral research has yet examined their relative effectiveness and efficiency in promoting and maintaining cooperation. To examine these issues, we observed participants interacting in a four-round public goods game (PGG) with or without gossip and punishment options, and a subsequent two-round trust game (TG). We manipulated gossip as the option to send notes about other group members to these members' future partners, and punishment as the option to assign deduction points to reduce other group members' outcomes with a fee-to-fine ratio of 1:3. Findings revealed that in the four-round PGG, the option to gossip increased both cooperation and individual earnings, whereas the option to punish had no overall effect on cooperation (but a positive effect on cooperation in the last two rounds of the PGG) and significantly decreased individual earnings. Importantly, the initial option to gossip made people more trusting and trustworthy in the subsequent TG when gossip was no longer possible, compared to the no-gossip condition. Thus, we provide some initial evidence that gossip may be more effective and efficient than punishment to promote and maintain cooperation.

  9. How to achieve a collaborative approach in health promotion: preferences and ideas of users of mental health services.

    Science.gov (United States)

    Pals, Regitze Anne Saurbrey; Hempler, Nana Folmann

    2018-02-12

    Collaborative approaches to consensus building or decision-making are beneficial in health-promoting activities targeting users of mental health services (users). However, little is known about how to achieve a collaborative approach in practice. The purpose of this study was to explore: (1) users' preferences and ideas related to achieving a collaborative approach in health-related communication and (2) perspectives of healthcare and social work professionals and family members on users' ideas and preferences. Data were collected through interactive workshops with users (n = 15), professionals (n = 21) and users' family members (n = 12). Data were analysed using systematic text condensation. Users provided three recommendations for establishing a collaborative approach in communication about health: (1) involving users in deciding the agenda and setting for health-promoting activities; (2) exchanging knowledge between users and professionals about health and values; and (3) exploring users' motivation for change. Users and professionals had diverging perceptions of the value of establishing a collaborative approach. Professionals regarded relationship building and health promotion as separate phenomena, whereas users perceived relationship building as inherently health promoting. Family members of users requested specific guidance and support with regard to clarifying and fulfilling the best possible support role as a family member. The findings suggest that a collaborative approach in health promotion may be difficult to achieve without a focus on professional development for healthcare and social work professionals. © 2018 Nordic College of Caring Science.

  10. Econometric Assessment of the Degree of Economic Convergence between Member States of the European Union

    Directory of Open Access Journals (Sweden)

    Elena Mădălina OPRIȚESCU

    2017-11-01

    Full Text Available One of the important objectives of the European Union is to support economic growth based on economic, social and territorial cohesion between Member States. Due to the accession of relatively poor countries to the European Union, maintaining cohesion is and will remain a major challenge, with cohesion policy having to support the reduction of imbalances between the old Member States and also support the development of less developed regions. One of the main measures adopted by the European authorities emphasizes the importance of increasing the degree of economic convergence between Member States by promoting a common market along with an economic and monetary union. In addition, increasing productivity and convergence within the EU are the foundations of the Lisbon Strategy and remain an important pillar of the Europe 2020 Growth Strategy.

  11. 「歐盟生質燃料指令2003/30/EC」之執行與成效 The Analysis for Execution and Effect of Directive 2003/30/EC on the Promotion of the Use of Biofuels or Other Renewable Fuels for Transport on European Union

    Directory of Open Access Journals (Sweden)

    王服清 Fu-Ching Wang

    2008-12-01

    Full Text Available 歐盟在 2003 年5 月8 日通過「歐盟促進使用生質燃料或其他可再生燃料於交通運輸工具之指令2003/30/EC」(以下簡稱「歐盟生質燃料指令2003/30/EC」)。依據該歐盟生質燃料指令第4 條第2 項之規定,歐盟執行委員會至遲應在2006 年12 月31 日之前,且之後每兩年,定期向歐洲議會及歐盟理事會,提出歐盟會員國有關生質燃料及其他可再生燃料使用之進展評估報告。據此規定,在2007 年1 月10 日,歐盟執委會提出歐盟生質燃料指令的執行情形與成效評估之第一份報告書。除此之外,「歐盟執委會下屬之能源暨運輸總署(Energy and Transport Directorate-General, European Commission)」在2006 年4 月至7 月期間,積極進行廣泛的公共諮詢活動,以收集對於生質燃料相關不同議題之各方意見。據以上述諸多資料以作吾人撰寫本論文之重要參考文獻,且期許本論文之研究成果可作為我國推動綠色能源政策或擬訂法制措施時之建言與回應。 European Union has passed directive 2003/30/EC which is concerning the promotion of the use of biofuels or other renewable fuels for transport on 8 May 2003 (abbreviate as “Biofuel Directive 2003/30/EC of European Union”. According to Article 4(2 of this directive, European Commission shall draw up an evaluation report for the European Parliament and for the Council on the progress made in the use of biofuels and other renewable fuels in the Member States by 31 December 2006 at the latest, and every two years thereafter. On the basis of this regulation, European Commission hands in the first report of execution situation and effect evaluation of Biofuel Directive 2003/30/EC of European Union. Besides, Energy and Transport Directorate-General, European Commission has positively proceeded wide public inquiry activities in order to gather the opinions of different topics about biofuels

  12. A comedy on TV to promote traffic safety.

    NARCIS (Netherlands)

    Wittink, R.D. Nelissen, W.J.A. & Hagenzieker, M.P.

    1990-01-01

    Since the end of 1987, a television-series has been promoting traffic safety in the Netherlands. This series named `The Oudenrijn-family' after a well-known traffic junction, is a comedy that treats important road safety themes in a casual and playful way. The members of the TV family, and their

  13. Minority faculty members' resilience and academic productivity: are they related?

    Science.gov (United States)

    Cora-Bramble, Denice; Zhang, Kehua; Castillo-Page, Laura

    2010-09-01

    To explore whether there is a relationship between resilience and academic productivity of minority faculty members in U.S. academic health centers. For the purposes of the study, the authors defined academic productivity as peer-reviewed and non-peer-reviewed publications, grants, and academic promotion. In 2007, the authors simultaneously collected quantitative and qualitative data by using a triangulation (mixed-method) design. Past participants in the Association of American Medical Colleges' Minority Faculty Career Development Seminar completed the Web-based 70-item Personal Resilience Questionnaire (PRQ). In addition, two focus groups were conducted with past seminar participants. Seventy-four minority faculty members completed the PRQ, and 15 participated in the two focus groups. The quantitative data showed a positive correlation between demographic, educational, and academic productivity variables and certain resilience subscale scores. Common themes that emerged from the qualitative data were categorized under four major domains: existing barriers to academic advancement, internal protective factors or cultural buffers, external institutional or environmental facilitators, and necessary attributes for ensuring academic productivity and advancement. Certain resilience subscales showed correlation with academic productivity of minority faculty members, and specific personal and/or cultural characteristics were identified as enablers. Minority faculty members may benefit from skill development and coaching that extends beyond the traditional scope of faculty development programs and that specifically targets modifiable resilience characteristics. Additional research is needed, but such nontraditional, resilience-centered intervention strategies may positively affect the advancement of minority faculty in academic medicine.

  14. Função dos músculos do assoalho pélvico : comparação entre mulheres praticantes do método Pilates e sedentárias

    OpenAIRE

    Lia Janaina Ferla Barbosa

    2014-01-01

    Pesquisas relacionadas os músculos do assoalho pélvico (MAP) tem ganhado espaço na última década principalmente quando se refere a alterações na sua função. A maioria das pesquisas encontradas na literatura diz respeito às disfunções dos MAP. É importante conhecer formas de condicionamento dessa musculatura que possa evitar a perda de função, seja por falta de exercícios os por alterações decorrentes do processo de envelhecimento. Sabe-se que em mulheres com disfunção o treinamento dos múscul...

  15. Perceived benefits and challenges of interprofessional education based on a multidisciplinary faculty member survey.

    Science.gov (United States)

    Lash, David Benjamin; Barnett, Mitchell J; Parekh, Nirali; Shieh, Anita; Louie, Maggie C; Tang, Terrill T-L

    2014-12-15

    To identify differences among faculty members in various health professional training programs in perceived benefits and challenges of implementing interprofessional education (IPE). A 19-item survey using a 5-point Likert scale was administered to faculty members across different health disciplines at a west coast, multicollege university with osteopathic medicine, pharmacy, and physician assistant programs. Sixty-two of 103 surveys (60.2%) were included in the study. Faculty members generally agreed that there were benefits of IPE on patient outcomes and that implementing IPE was feasible. However, group differences existed in belief that IPE improves care efficiency (p=0.001) and promotes team-based learning (p=0.001). Program divergence was also seen in frequency of stressing importance of IPE (p=0.009), preference for more IPE opportunities (p=0.041), and support (p=0.002) within respective college for IPE. Despite consensus among faculty members from 3 disciplines that IPE is invaluable to their curricula and training of health care students, important program level differences existed that would likely need to be addressed in advance IPE initiatives.

  16. What works in Indigenous tobacco control? The perceptions of remote Indigenous community members and health staff.

    Science.gov (United States)

    Johnston, Vanessa; Thomas, David P

    2010-04-01

    To explore the perceptions of remote Indigenous community members and health staff regarding the acceptability and effectiveness of different tobacco control health promotion interventions. Qualitative methods were used for this exploratory study, including interviews with remote Indigenous community members and health staff, as well as observations of the delivery of different tobacco control activities in three remote communities in the Northern Territory (NT). Several tobacco control interventions for which there is strong evidence in other settings were generally perceived as acceptable and efficacious in the remote Indigenous setting. Primary care interventions, such as brief advice and pharmaceutical quitting aids, when available and accessible, were perceived as important and effective strategies to help people quit, as were the promotion of smokefree areas. By contrast unmodified Quit programs were perceived to have questionable application in this context and there were conflicting findings regarding taxation increases on tobacco and social marketing campaigns. Several evidence-based 'mainstream' activities are perceived to be acceptable to this population, but we may also need to address the concerns raised by health staff and community members about the acceptability of some unmodified activities. Additionally, organisational barriers within the health system may be contributing to the reduced effectiveness of tobacco control in this setting.

  17. Evaluation of a nursing student health fair program: Meeting curricular standards and improving community members' health.

    Science.gov (United States)

    Salerno, John P; McEwing, Evan; Matsuda, Yui; Gonzalez-Guarda, Rosa M; Ogunrinde, Olutola; Azaiza, Mona; Williams, Jessica R

    2018-04-17

    Public health nursing (PHN) is an essential component of baccalaureate nursing education. In order to build PHN competencies, universities must design and operationalize meaningful clinical activities addressing community and population health. Currently, there is a paucity of literature delineating best practices for promoting competency in PHN. The purpose of this manuscript is to describe a PHN-student health fair program as a means for meeting undergraduate PHN curricular standards, and to report results of an evaluation conducted examining its effectiveness in improving community member's health knowledge. Health fairs were held at community agencies that served the homeless or victims of intimate partner violence. A total of 113 community members that attended a health fair were assessed at baseline and immediate posttest using open-ended questionnaires. The design of the health fairs included a community assessment, intervention, and evaluation flow that followed the nursing process. We report that results from participants surveyed indicated that PHN-student delivered health fairs improved health knowledge among community members in this sample (p = .000). Health fairs conducted by PHN students appear to be promising community health promotion and disease prevention interventions that can serve as an effective strategy for teaching PHN student competencies and facilitating engagement with the community. © 2018 Wiley Periodicals, Inc.

  18. Evolutionary Pattern and Regulation Analysis to Support Why Diversity Functions Existed within PPAR Gene Family Members

    Directory of Open Access Journals (Sweden)

    Tianyu Zhou

    2015-01-01

    Full Text Available Peroxisome proliferators-activated receptor (PPAR gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63 homology sequences of PPAR genes from 31 species were collected and analyzed. The results showed that three isolated types of PPAR gene family may emerge from twice times of gene duplication events. The conserved domains of HOLI (ligand binding domain of hormone receptors domain and ZnF_C4 (C4 zinc finger in nuclear in hormone receptors are essential for keeping basic roles of PPAR gene family, and the variant domains of LCRs may be responsible for their divergence in functions. The positive selection sites in HOLI domain are benefit for PPARs to evolve towards diversity functions. The evolutionary variants in the promoter regions and 3′ UTR regions of PPARs result into differential transcription factors and miRNAs involved in regulating PPAR members, which may eventually affect their expressions and tissues distributions. These results indicate that gene duplication event, selection pressure on HOLI domain, and the variants on promoter and 3′ UTR are essential for PPARs evolution and diversity functions acquired.

  19. Evolutionary Pattern and Regulation Analysis to Support Why Diversity Functions Existed within PPAR Gene Family Members.

    Science.gov (United States)

    Zhou, Tianyu; Yan, Xiping; Wang, Guosong; Liu, Hehe; Gan, Xiang; Zhang, Tao; Wang, Jiwen; Li, Liang

    2015-01-01

    Peroxisome proliferators-activated receptor (PPAR) gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63 homology sequences of PPAR genes from 31 species were collected and analyzed. The results showed that three isolated types of PPAR gene family may emerge from twice times of gene duplication events. The conserved domains of HOLI (ligand binding domain of hormone receptors) domain and ZnF_C4 (C4 zinc finger in nuclear in hormone receptors) are essential for keeping basic roles of PPAR gene family, and the variant domains of LCRs may be responsible for their divergence in functions. The positive selection sites in HOLI domain are benefit for PPARs to evolve towards diversity functions. The evolutionary variants in the promoter regions and 3' UTR regions of PPARs result into differential transcription factors and miRNAs involved in regulating PPAR members, which may eventually affect their expressions and tissues distributions. These results indicate that gene duplication event, selection pressure on HOLI domain, and the variants on promoter and 3' UTR are essential for PPARs evolution and diversity functions acquired.

  20. "Making it personal": ideology, the arts, and shifting registers in health promotion.

    Science.gov (United States)

    Ruthven, Jessica S

    2016-01-01

    In South Africa, health promotion related to HIV/AIDS has been characterised as a component of public health prevention. It has heavily utilised global health ideology to construct promotional messages that rely on neoliberal models of individual, responsible health citizenship. However, after nearly 30 years of public health messaging, there have been only minor shifts in the country's HIV prevalence rates; it has become apparent that there is disconnect between policy, programmes, and target audiences. Debates about where this disconnect occurs tend to focus on the role of problems in biomedical knowledge translation or with structural inequalities that lead to health inequity. As debates increase, artists involved in health have emerged to address an additional reason: audience interpellation. In this article, I interrogate relationships between health promotion ideology and processes of interpellation. I suggest that disconnect between the two has roots in the tone of programming, the ways sociality is constructed within health promotion, and the kind of subject which global prevention programmes seek to constitute. Using a case study, I illustrate how public health ideology is made actionable through arts practice. While conventional health promotion programmes address populations in a way that allows individuals to distance themselves, members of South Africa's arts sector have worked to integrate prevention and care in a way that bolsters interpellation through making messages personal. The case study presents one performance but is informed by my broader research with over 20 theatrical groups conducted during 18 months of fieldwork. Analysis of the production reveals that artists act as mediators between population-level public health messages and individuals through the embodied technologies of applied theatre. However, I argue that artists also create space for participants to reimagine configurations of care, responsibility, and intimacy within health

  1. Nudging children towards whole wheat bread: a field experiment on the influence of fun bread roll shape on breakfast consumption.

    Science.gov (United States)

    van Kleef, Ellen; Vrijhof, Milou; Polet, Ilse A; Vingerhoeds, Monique H; de Wijk, René A

    2014-09-02

    Many children do not eat enough whole grains, which may have negative health consequences. Intervention research is increasingly focusing on nudging as a way to influence food choices by affecting unconscious behavioural processes. The aim of this field study was to examine whether the shape of bread rolls is able to shift children's bread choices from white to whole wheat during breakfast to increase whole grain intake. In a between-subjects experiment conducted at twelve primary schools in the Netherlands, with school as the unit of condition assignment, children were exposed to an assortment of white and whole wheat bread rolls, both varying in shape (regular versus fun). Children were free to choose the type and number of bread rolls and toppings to eat during breakfast. Consumption of bread rolls was measured at class level via the number of bread rolls before and after breakfast. In addition, children (N = 1113) responded to a survey including questions about the breakfast. Results of the field experiment showed that about 76% of bread consumption consisted of white bread rolls. Consumption of white bread rolls did not differ according to shape (all P-values > 0.18). However, presenting fun-shaped whole wheat bread rolls almost doubled consumption of whole wheat bread (P = 0.001), particularly when the simultaneously presented white bread rolls had a regular shape (interaction P = 0.02). Survey results suggest that slight increases in perceived pleasure and taste are associated with these effects. Overall, presenting whole wheat bread in fun shapes may be helpful in increasing consumption of whole wheat bread in children. Future research could examine how improving the visual appeal of healthy foods may lead to sustained behaviour changes.

  2. Factors and symptoms associated with work stress and health-promoting lifestyles among hospital staff: a pilot study in Taiwan

    Directory of Open Access Journals (Sweden)

    Tsai Yueh-Chi

    2012-07-01

    Full Text Available Abstract Background Healthcare workers including physicians, nurses, medical technicians and administrative staff experience high levels of occupational stress as a result of heavy workloads, extended working hours and time-related pressure. The aims of this study were to investigate factors associated with work stress among hospital staff members and to evaluate their health-promoting lifestyle behaviors. Methods We conducted a cross-sectional study from May 1, 2010 to July 30, 2010 and recruited 775 professional staff from two regional hospitals in Taiwan using purposive sampling. Demographic data and self-reported symptoms related to work-related stress were collected. Each subject completed the Chinese versions of the Job Content Questionnaire (C-JCQ and The Health-Promoting Lifestyle Profile (HPLSP. Linear and binary regression analyses were applied to identify associations between these two measurements and subjects’ characteristics, and associations between the two measurements and stress symptoms. Results Self-reported symptoms of work-related stress included 64.4% of subjects reporting nervousness, 33.7% nightmares, 44.1% irritability, 40.8% headaches, 35.0% insomnia, and 41.4% gastrointestinal upset. C-JCQ scores for psychological demands of the job and discretion to utilize skills had a positive correlation with stress-related symptoms; however, the C-JCQ scores for decision-making authority and social support correlated negatively with stress-related symptoms except for nightmares and irritability. All items on the HPLSP correlated negatively with stress-related symptoms except for irritability, indicating an association between subjects’ symptoms and a poor quality of health-promoting lifestyle behaviors. Conclusions We found that high demands, little decision-making authority, and low levels of social support were associated with the development of stress-related symptoms. The results also suggested that better performance on

  3. Factors and symptoms associated with work stress and health-promoting lifestyles among hospital staff: a pilot study in Taiwan.

    Science.gov (United States)

    Tsai, Yueh-Chi; Liu, Chieh-Hsing

    2012-07-16

    Healthcare workers including physicians, nurses, medical technicians and administrative staff experience high levels of occupational stress as a result of heavy workloads, extended working hours and time-related pressure. The aims of this study were to investigate factors associated with work stress among hospital staff members and to evaluate their health-promoting lifestyle behaviors. We conducted a cross-sectional study from May 1, 2010 to July 30, 2010 and recruited 775 professional staff from two regional hospitals in Taiwan using purposive sampling. Demographic data and self-reported symptoms related to work-related stress were collected. Each subject completed the Chinese versions of the Job Content Questionnaire (C-JCQ) and The Health-Promoting Lifestyle Profile (HPLSP). Linear and binary regression analyses were applied to identify associations between these two measurements and subjects' characteristics, and associations between the two measurements and stress symptoms. Self-reported symptoms of work-related stress included 64.4% of subjects reporting nervousness, 33.7% nightmares, 44.1% irritability, 40.8% headaches, 35.0% insomnia, and 41.4% gastrointestinal upset. C-JCQ scores for psychological demands of the job and discretion to utilize skills had a positive correlation with stress-related symptoms; however, the C-JCQ scores for decision-making authority and social support correlated negatively with stress-related symptoms except for nightmares and irritability. All items on the HPLSP correlated negatively with stress-related symptoms except for irritability, indicating an association between subjects' symptoms and a poor quality of health-promoting lifestyle behaviors. We found that high demands, little decision-making authority, and low levels of social support were associated with the development of stress-related symptoms. The results also suggested that better performance on or a higher frequency of health-promoting life-style behaviors might

  4. Função renal em pacientes com leishmaniose muco-cutânea tratados com antimoniais pentavalentes

    Directory of Open Access Journals (Sweden)

    Joel Paulo Russomano Veiga

    1985-12-01

    Full Text Available Avaliou-se a função renal em 10 pacientes com leishmaniose muco-cutânea tratados com glucantime (antimoniato de Meglumine, Rhodia ou Pentostam (estibogluconato de sólio, Wellcome. Durante o uso das drogas, verificou-se a existência de um defeito na capacidade concentrante do rim, obtendo-se menores valores da osmolaridade urinária máxima e de depuração negativa máxima de água livre, neste período, em relação aos testes efetuados antes do tratamento. A capacidade de concentração urinária normalizou-se em 5, de 8 pacientes estudados no período de 15 a 30 dias, após a suspensão dos medicamentos, embora com valores de osmolaridade urinária máxima inferiores aos obtidos antes do tratamento. Em dois pacientes surgiu proteínúria, acima de 150 mg/dia, com o uso dos antimoniais, normalizando-se posteriormente. A depuração de creatinina endógena não se alterou significativamente com o uso das drogas. Os resultados sugerem que os antimoniais pentavalentes podem levar a uma disfunção tubular renal, caracterizada por um defeito na capacidade de concentrar a urina, reversível após a retirada dos medicamentos.

  5. Celulares, Funções pós-midiáticas, Cidade e Mobilidade Mobile phones, postmediatic functions, city and mobility

    Directory of Open Access Journals (Sweden)

    André Lemos

    2010-11-01

    Full Text Available O objetivo desse artigo é compreender a relação entre as novas tecnologias de comunicação e informação(TICs e o espaço urbano a partir de uma discussão sobre a mobilidade. Para tanto, o artigo propõe alguns princípios para a compreensão desse fenômeno: 1 a nova configuração comunicacional, que chamo de funções “pós-massivas” em contraposição à ideia de mídias de massa; 2 as novas funções e heterotopias dos lugares com a emergência de “territórios informacionais”, compreendendo aqui comoas novas tecnologias de comunicação produzem socialmente o espaço e redefinem as dimensões locais. Analisaremos o uso dos telefones celulares em alguns projetos em mídias locativas (tecnologias e serviços baseados em localização para ilustrar o nosso propósito.

  6. Glucokinase gene promoter -30G>A polymorphism: a cross-sectional association study with obesity, diabetes Mellitus, hyperlipidemia, hypertension and metabolic syndrome in an Iranian hospital

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Oladi

    2012-08-01

    Full Text Available OBJECTIVE: A -30G>A single nucleotide polymorphism in the promoter region of the glucokinase gene has been previously associated with obesity, insulin resistance and diabetes. The present study aimed to evaluate the association of this polymorphism with obesity and its comorbidities in a population from Northeast Iran. METHODS: Five hundred and forty-two subjects aged 18 to 65 years were included in the study and divided into normal (BMI30, n=187 groups. All subjects were genotyped for the -30G>A polymorphism using the polymerase chain reaction-restriction fragment length polymorphism technique. RESULTS: The genotypes and allele frequencies of the three groups did not differ significantly (p>0.05. When the study population was categorized according to diabetes mellitus, hyperlipidemia, hypertension and metabolic syndrome status, no significant difference in -30G>A genotypes and alleles was found between the subgroups with and without these disorders (p>0.05, apart from a significantly higher frequency of the G allele in the hyperlipidemic vs. non-hyperlipidemic subgroup (pA polymorphism and high body mass index in the Iranian population.

  7. HEALS Hypertension Control Program: Training Church Members as Program Leaders.

    Science.gov (United States)

    Dodani, Sunita; Beayler, Irmatine; Lewis, Jennifer; Sowders, Lindsey A

    2014-01-01

    Health disparities related to cardiovascular diseases (CVDs) including stroke have remained higher in the African-Americans (AAs) than in other populations. HEALS is a faith-based hypertension (HTN) control program modified according to AA community needs, and delivered by the church-lay members called church health advisors (CHAs). This study examined the feasibility and acceptability of training CHAs as HEALS program leaders. Four CHAs completed a 10-hour HEALS program training workshop at the Church, conducted by the nutrition experts. Workshop was evaluated by CHAs on their level of satisfaction, clarity of contents covered and comfort in delivery the program to the church congregation. The overall six main HEALS curriculum components were completed. Workshop was highly evaluated by CHAs on length of training, balance between content and skills development, and level of satisfaction with program delivery. Church-based culturally modified health promotion interventions conducted by the community lay members may be a way to reduce health disparities in ethnic minorities.

  8. Health promotion competencies: providing a road map for health promotion to assume a prominent role in global health.

    Science.gov (United States)

    Shilton, Trevor

    2009-06-01

    Understanding of health and its determinants is rapidly expanding and changing. The emergence of chronic diseases as the leading cause of global disease burden and improved understanding of social determinants of health has brought greater focus to the role of prevention in health. The IUHPE has shown outstanding leadership through the Galway Consensus Statement. Its three recommendations appropriately focus on stimulating dialogue, developing global consensus and communicating the results to key stakeholders. The IUHPE can further enhance progress of the statement by developing participative processes to ensure engagement and ownership by its members. The Galway Consensus Statement can be used to advance professional standards in global health promotion by: (1) providing a common language by which health promotion and its meaning can be communicated to others; (2) providing a framework for building capacity in the health promotion workforce and in the health workforce in general; (3) providing international consensus for consistency in university health promotion courses; (4) providing a framework for credentialing in health promotion; (5) better informing health promotion engagement with other significant workforce sectors and advancing partnership as a key way of working. A vital further application of the Galway Consensus Statement is to inform advocacy. Advocacy is vital to ensure health promotion is better resourced and prioritized by policy makers. Advocacy and communication are vital tools to highlight the evidence, establish the policy fit and infrastructure requirements of health promotion, and present health promotion solutions based on evidence of effectiveness.

  9. A função de controle nos sistemas integrados de manufatura

    Directory of Open Access Journals (Sweden)

    Flavio Cesar F Fernandes

    1991-06-01

    Full Text Available Faz-se uma proposição de vários conceitos atinentes ao gerenciamento da produção, muitos dos quais são válidos também para os Sistemas de Manufatura Convencional, mas que estão aqui colocados dentro do contexto dos Sistemas Integrados de Manufatura (SIMs, que são os sistemas desenvolvidos sob a filosofia de fabricação CIM ('Computer Integrated Manufacturing = Manufatura Integrada por Computador. Mostra-se que a integração depende basicamente da função controle.Manufacturing integration is reviewed and various concepts and definitions founded in literature are presented for conventional and automated manufacturing systems. The survey emphasizes information system management and control importance in order to improve manufacturing functions integration.

  10. Targeting Obesity through Health Promotion Programs for School Staff

    Science.gov (United States)

    Herbert, Patrick C.; Lohrmann, David K.; Hall, Cougar

    2017-01-01

    Health promotion programs for school staff are an overlooked and under-utilized resource that can lead to reductions in overweight and obesity among teachers and other staff members if implemented properly. In addition to increasing the overall staff wellness, boosting morale, increasing productivity, improving academic achievement, providing…

  11. Marcadores práticos de função renal em pacientes com cistinose

    OpenAIRE

    Guimaraes,Luciana Pache de Faria; Neri,Letícia Aparecida Lopes; Sumita,Nairo Massakasu; Vaisbich,Maria Helena

    2012-01-01

    INTRODUÇÃO: Cistinose é uma doença sistêmica, autossômica recessiva, que leva à insuficiência renal crônica na infância, a não ser que o tratamento com cisteamina seja iniciado precocemente. Mesmo nestas condições, os pacientes evoluem para doença renal crônica terminal por volta da segunda década da vida. Portanto, a avaliação da função renal é essencial neste grupo de pacientes. OBJETIVO: Avaliar e correlacionar a cistatina C, creatinina sérica e o clearance de creatinina pela Fórmula de Sc...

  12. Equivalência de dulçor e poder edulcorante de edulcorantes em função da temperatura de consumo em bebidas preparadas com chá-mate em pó solúvel Equi-sweetness and sweetening power of different sweetening agents in differents temperatures of consumption of tea drink in soluble power

    Directory of Open Access Journals (Sweden)

    Juliana Maria Porto Cardoso

    2004-09-01

    Full Text Available No presente estudo foi verificado o efeito da temperatura de consumo na equivalência de doçura e no poder edulcorante de diferentes agentes adoçantes em bebida de chá-mate em pó solúvel. Foram avaliados: aspartame, sucralose, mistura ciclamato/sacarina 2:1, Stevia e acessulfame-K, tendo como referência a sacarose. Todos os estudos foram realizados a 6±2ºC e a 45±2ºC. Primeiramente foi determinada a doçura ideal, utillizando-se escala do ideal com 30 provadores consumidores da bebida. Em seguida, foi determinada a doçura equivalente à sacarose (na doçura considerada ideal para cada edulcorante estudado, e seu poder edulcorante nas duas temperaturas de estudo. Para tal foi aplicado o método de estimação de magnitude, utilizando-se uma equipe de 10 provadores selecionados e treinados. A doçura ideal de sacarose foi de 8,3% para a bebida de chá-mate solúvel, sem diferença significativa entre as temperaturas de estudo. Ocorreram diferenças sensoriais importantes em função da temperatura, pois, enquanto para alguns edulcorantes o aumento de temperatura provocou diminuição na potência edulcorante, para outros foi observado aumento do poder edulcorante. Portanto, não se deve generalizar as alterações no poder edulcorante em função da temperatura, pois ela pode variar em função da classe química envolvida e do meio de dispersão em que se encontra.In this work the effect of temperature of consumption in the equi-sweetness and sweetening power of different sweetening agents was verified in tea drink in soluble powder. The panelists had evaluated: aspartame, sucralose, mixture of cyclamate/saccharin (2:1, Stevia [Stevia rebaudiana (Bert. Bertoni] and acesulfame-K as sweeteners, having sucrose as reference. All sensory tests were carried-out at 6±2ºC and 45±2ºC. Firstly the ideal sweetness was determined by just-about-right scale with 30 consumers of tea drink. After the ideal sweetness of sucrose determination, the

  13. Compresive Strength for FRC Member using Silica Fume

    OpenAIRE

    R.M.Damgir,; Y.M.Ghugal

    2011-01-01

    The compressive strength of concrete was obtained by conducting tests on standard cubes of size 150X 150X150 mm size with fibers 0 to 5% with an increment of 0.5% and Silica Fume of 5%.The compressivestrength was determined by carrying out compressive test by using UTM. Slump loss increases with increase in Fiber Volume Crack Width reduces as percentage Fiber Volume increases and Crack width varying between 0.75 to 1.30 mm for 28 days concrete strength. Toughness of concrete member increases ...

  14. South Carolina Guide for Sales Promotion. Marketing Education.

    Science.gov (United States)

    Elliott, Ronald T.

    This guide presents a competency-based curriculum for a high school course in sales promotion. It addresses all three domains of learning: psychomotor, cognitive, and affective. Activities suggested in the guide deal with getting along with others, with supervisors or staff members, and with small or large groups. The guide, which can be used with…

  15. Validation of a Node-Centered Wall Function Model for the Unstructured Flow Code FUN3D

    Science.gov (United States)

    Carlson, Jan-Renee; Vasta, Veer N.; White, Jeffery

    2015-01-01

    In this paper, the implementation of two wall function models in the Reynolds averaged Navier-Stokes (RANS) computational uid dynamics (CFD) code FUN3D is described. FUN3D is a node centered method for solving the three-dimensional Navier-Stokes equations on unstructured computational grids. The first wall function model, based on the work of Knopp et al., is used in conjunction with the one-equation turbulence model of Spalart-Allmaras. The second wall function model, also based on the work of Knopp, is used in conjunction with the two-equation k-! turbulence model of Menter. The wall function models compute the wall momentum and energy flux, which are used to weakly enforce the wall velocity and pressure flux boundary conditions in the mean flow momentum and energy equations. These wall conditions are implemented in an implicit form where the contribution of the wall function model to the Jacobian are also included. The boundary conditions of the turbulence transport equations are enforced explicitly (strongly) on all solid boundaries. The use of the wall function models is demonstrated on four test cases: a at plate boundary layer, a subsonic di user, a 2D airfoil, and a 3D semi-span wing. Where possible, different near-wall viscous spacing tactics are examined. Iterative residual convergence was obtained in most cases. Solution results are compared with theoretical and experimental data for several variations of grid spacing. In general, very good comparisons with data were achieved.

  16. Promoting Continuous Quality Improvement in Online Teaching: The META Model

    Science.gov (United States)

    Dittmar, Eileen; McCracken, Holly

    2012-01-01

    Experienced e-learning faculty members share strategies for implementing a comprehensive postsecondary faculty development program essential to continuous improvement of instructional skills. The high-impact META Model (centered around Mentoring, Engagement, Technology, and Assessment) promotes information sharing and content creation, and fosters…

  17. 77 FR 34029 - National Security Education Board Members Meeting; Cancellation of Meeting

    Science.gov (United States)

    2012-06-08

    ... DEPARTMENT OF DEFENSE Office of the Secretary National Security Education Board Members Meeting... of the National Security Education Board. This meeting was to be held on June 20, 2012, from 8:30 a.m. to 2 p.m. at Defense Language and National Security Education Office, 1101 Wilson Boulevard, Suite...

  18. Elections of members to the Governing Board of the Pension Fund

    CERN Multimedia

    Pension Fund

    2005-01-01

    This year, one member and two alternates are to be elected. The candidate who obtains the most votes will be elected member and the other candidates will be their alternates. These elections will take place following the timetable given below: Monday 31 October 2005 Second publication of the candidates' publicity in the Bulletin and distribution of the ballot papers at CERN. Monday 21 November 2005 Voting closes at 12:00. Counting of votes from 14:30. Tuesday 22 November 2005 Forwarding of results to the Communications Section for publication in the Bulletin of 28 November. CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH PENSION FUND ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate: Name: MARTEL First Name: Pedro I arrived at CERN as a Staff member in 1995, and have been working with Engineering Databases since then. I ...

  19. Elections of members to the Governing Board of the Pensions Fund

    CERN Multimedia

    Pension Fund

    2004-01-01

    This year, two members and two alternates are to be elected. The candidates who obtain most votes will be elected members and the other candidates will be their alternates. Timetable (extract) : Monday 1 November 2004 Second publication of the candidates' publicity in the Bulletin (see thereafter) and distribution of the ballot papers at CERN. Monday 22 November 2004 Voting closes at 12 hrs. Counting of votes from 14.30 hrs. Tuesday 23 November 2004 Forwarding of results to the Communications Section for publication in the Bulletin of 29 November. ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE CERN EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CAISSE DE PENSIONS / PENSION FUND ELECTIONS - Pension Fund This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate: Name : CHIAVERI First Name : Enrico I have been a CERN staff member since 1973 and have a...

  20. 77 FR 40529 - Soybean Promotion and Research: Amend the Order To Adjust Representation on the United Soybean Board

    Science.gov (United States)

    2012-07-10

    ... Service 7 CFR Part 1220 [Doc. No. AMS-LS-12-0022] Soybean Promotion and Research: Amend the Order To... in 2009. As required by the Soybean Promotion, Research, and Consumer Information Act (Act... members from 69 to 70. These changes would be reflected in the Soybean Promotion and Research Order (Order...

  1. Feedback about Teaching in Higher Ed: Neglected Opportunities to Promote Change.

    Science.gov (United States)

    Gormally, Cara; Evans, Mara; Brickman, Peggy

    2014-01-01

    Despite ongoing dissemination of evidence-based teaching strategies, science teaching at the university level is less than reformed. Most college biology instructors could benefit from more sustained support in implementing these strategies. One-time workshops raise awareness of evidence-based practices, but faculty members are more likely to make significant changes in their teaching practices when supported by coaching and feedback. Currently, most instructional feedback occurs via student evaluations, which typically lack specific feedback for improvement and focus on teacher-centered practices, or via drop-in classroom observations and peer evaluation by other instructors, which raise issues for promotion, tenure, and evaluation. The goals of this essay are to summarize the best practices for providing instructional feedback, recommend specific strategies for providing feedback, and suggest areas for further research. Missed opportunities for feedback in teaching are highlighted, and the sharing of instructional expertise is encouraged. © 2014 M. Evans et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  2. The retinoid X receptor response element in the human aldehyde dehydrogenase 2 promoter is antagonized by the chicken ovalbumin upstream promoter family of orphan receptors

    NARCIS (Netherlands)

    Pinaire, J; Hasanadka, R; Fang, M; Chou, WY; Stewart, MJ; Kruijer, W; Crabb, D

    2000-01-01

    Two tandem sites in the aldehyde dehydrogenase 2 promoter (designated FP330-5' and FP330-3') that bind members of the nuclear receptor superfamily mere recently identified. Antibodies against apolipoprotein regulatory protein (ARP-1) altered DNA-protein interactions in electrophoretic mobility shift

  3. Prevention of carrageenan-induced pleurisy in mice by anti-CD30 ligand monoclonal antibody

    DEFF Research Database (Denmark)

    Di Paola, Rosanna; Di Marco, Roberto; Mazzon, Emanuela

    2004-01-01

    CD30 ligand (CD30L) and its receptor CD30 are members of the tumor necrosis factor (TNF) and TNF receptor superfamilies that play a major role in inflammation and immune regulation. To gain insight into the in vivo role of CD30L/CD30 in inflammatory diseases, we have used carrageenan (CAR)-induce...

  4. Impact of the Cognitive-Functional (Cog-Fun) Intervention on Executive Functions and Participation Among Children With Attention Deficit Hyperactivity Disorder: A Randomized Controlled Trial.

    Science.gov (United States)

    Hahn-Markowitz, Jeri; Berger, Itai; Manor, Iris; Maeir, Adina

    We examined the effect of the Cognitive-Functional (Cog-Fun) occupational therapy intervention on executive functions and participation among children with attention deficit hyperactivity disorder (ADHD). We used a randomized, controlled study with a crossover design. One hundred and seven children age 7-10 yr diagnosed with ADHD were allocated to treatment or wait-list control group. The control group received treatment after a 3-mo wait. Outcome measures included the Behavior Rating Inventory of Executive Function (BRIEF) and the Canadian Occupational Performance Measure (COPM). Significant improvements were found on both the BRIEF and COPM after intervention with large treatment effects. Before crossover, significant Time × Group interactions were found on the BRIEF. This study supports the effectiveness of the Cog-Fun intervention in improving executive functions and participation among children with ADHD. Copyright © 2017 by the American Occupational Therapy Association, Inc.

  5. Transactivation of the proximal promoter of human oxytocin gene by TR4 orphan receptor

    International Nuclear Information System (INIS)

    Wang, C.-P.; Lee, Y.-F.; Chang, C.; Lee, H.-J.

    2006-01-01

    The human testicular receptor 4 (TR4) shares structural homology with members of the nuclear receptor superfamily. Some other members of this superfamily were able to regulate the transcriptional activity of the human oxytocin (OXT) promoter by binding to the first DR0 regulatory site. However, little investigation was conducted systematically in the study of the second dDR4 site of OXT proximal promoter, and the relationship between the first and the second sites of OXT promoter. Here, we demonstrated for the first time that TR4 could increase the proximal promoter activity of the human OXT gene via DR0, dDR4, and OXT (both DR0 and dDR4) elements, respectively. TR4 might induce OXT gene expression through the OXT element in a dose-dependent manner. However, there is no synergistic effect between DR0 and dDR4 elements during TR4 transactivation. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression

  6. Assessment of non-cost barriers to renewable energy growth in EU Member States - AEON

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-05-15

    The accelerated deployment of renewable energy technologies has become a major priority for public policy makers across the globe. In the last two decades, most of the debate concerning the promotion of renewables was focused on the financial support schemes and on improving grid access conditions for renewable electricity. Of course, these are crucial issues which will continue to deserve serious attention in the future. However, during the last few years, the importance of tackling non-financial and non-technical barriers to renewable electricity, heat and transport has gained the attention of many policy analysts. In June 2009, Directive 2009/28/EC on the promotion of the use of energy from renewable sources, entered into force. The articles 13, 14 and 16 of the Directive contain a number of requirements for Member States to address or remove non-cost barriers to the increased deployment of renewable energy sources. This study presents among others an overview of these barriers in all EU Member States; their history, their impact on renewable energy deployment and suggestions for policy solutions, where feasible. Separate studies were carried out for 27 EU-countries and made available in a zip-file.

  7. Breast-feeding trends and the breast-feeding promotion programme in the Philippines.

    Science.gov (United States)

    Williamson, N E

    1990-03-01

    Breastfeeding (BF) duration and incidence have declined in the Philippines since 1973, particularly among urban, better-educated and higher income groups. As more and more women move into these modern groups, BF may continue to decline, making attempts to decrease fertility more difficult. The National Movement for the Promotion of Breastfeeding (NMPB) seeks to overcome the declines by encouraging a wide range of BF promotion activities including improving hospital practices and implementing a 5-year plan. In 1988, the 2nd 5 years of the United Nations International Children's Emergency Fund support for BF promotion started as part of a program to strengthen health services for child survival. Also in 1988, the Ministry of Health directed private hospitals to have rooming-in. In 1984, BF promotion messages began in the mass media. In 1983, NMPB was set up. The NMPB is housed in the Department of Public Health and has 30 member agencies: 14 governmental organizations and 25 nongovernmental agencies/institutions. From 1982-84 a longitudinal study on decision making regrading infant feeding practices was started. A hospital-based BF promotion program was started in the city of Baguio in the 70s. "Rooming-in" is required in government facilities, but there is a need for education programs for women so that they will continue their healthy practices at home. Challenges of the Philippines BF promotion program corner 4 areas: 1) health facilities; 2) information, education, and communication; 3) training; and 4) outreach. Research activities for the future include: 1) continued monitoring of patterns and trends of BF, including evaluation of the 1988 national survey; 2) analysis of the impact of "rooming-in" programs; 3) studies on the cost effectiveness of different strategies for increasing BF incidence and length and modifying BF practices and beliefs; 4) testing of strategies for helping working women to breastfeed; 5) research on obstacles to BF in private hospitals

  8. A new method for promoting lily flowering

    African Journals Online (AJOL)

    Jane

    2011-08-08

    Aug 8, 2011 ... FT is thought to be the florigen in plants. In this research, a new method for promoting lily flowering was introduced. The function of FT gene cloned from Arabidopsis on promoting lily flowering was analyzed. pET-30a-FT vector was constructed to indicate the expression of FT:eGFP fuse protein in.

  9. Does race still matter in nursing? The narratives of African-American nursing faculty members.

    Science.gov (United States)

    Beard, Kenya V; Julion, Wrenetha A

    The rise in undergraduate enrollment of African-American students has not translated into more African-American faculty members, although they could mentor minority students and promote an ethos that encourages their academic success. Discrimination against African-American faculty members continues, which could lessen their presence. This study explored the narratives of 23 African-American faculty members to determine if race still matters in nursing. A narrative approach grounded in social constructionism and critical race theory was used to illustrate the journey of African-American faculty into and throughout academia and to reveal factors related to decisions to enter and remain in academia. Most of the participants stated that they faced racial discrimination that tested their resilience and reinforced their commitment to the academy. Intentional actions and open discourse could strengthen institutional commitments to racial diversity and facilitate the recruitment and retention of racially diverse nursing faculties. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Australian health promotion practitioners' perceptions on evaluation of empowerment and participation.

    Science.gov (United States)

    Brandstetter, Susanne; McCool, Megan; Wise, Marilyn; Loss, Julika

    2014-03-01

    Although participation and empowerment are hallmarks of the WHO vision of health promotion, it is acknowledged that they are difficult to evaluate. Devising adequate study designs, indicators and methods for the assessment of participation and empowerment should consider the experiences, concerns and constraints of health promotion practitioners. The aim of this study was to investigate health promotion practitioners' perspectives on general and methodological aspects of evaluation of empowerment and participation. Semi-structured interviews were conducted with 17 experienced practitioners in community-based health promotion in New South Wales, Australia. The interviews covered benefits of and barriers to the evaluation of participation and empowerment, key indicators and methodological aspects. Interview transcripts were examined using thematic content analysis. The idea of evaluating empowerment and participation is supported by health promotion practitioners. Including indicators of empowerment and participation in the evaluation could also emphasise-to practitioners and citizens alike-the value of involving and enabling community members. The interviews highlighted the importance of a receptive environment for evaluation of empowerment and participation to take root. The resistance of health authorities towards empowerment indicators was seen as a challenge for funding evaluations. Community members should be included in the evaluation process, although interviewees found it difficult to do so in a representative way and empowering approach. Qualitative methods might capture best whether empowerment and participation have occurred in a programme. The positive experiences that the interviewees made with innovative qualitative methods encourage further investment in developing new research designs.

  11. Early impairment of cognitive functions in Parkinson's disease Comprometimento precoce das funções cognitivas na doença de Parkinson

    Directory of Open Access Journals (Sweden)

    Florindo Stella

    2007-06-01

    Full Text Available BACKGROUND: Impairment in non-motor functions such as disturbances of some executive functions are also common events in Parkinson's disease patients. OBJECTIVE: To verify the performance of Parkinson's disease patients in activities requiring visuoconstructive and visuospatial skills. METHOD: Thirty elderly patients with mild or moderate stages of Parkinson's disease were studied. The assessment of the clinical condition was based on the unified Parkinson's disease rating scale (56.28; SD=33.48, Hoehn and Yahr (2.2; SD=0.83, Schwab and England (78.93%, clock drawing test (7.36; SD=2.51, and mini-mental state examination (26.48; SD=10.11. Pearson's correlation and stepwise multiple regression were used for statistical analyses. RESULTS: The patients presented deterioration in visuospatial and visuoconstructive skills. CONCLUSION: The clock drawing test proved to be a useful predictive tool for identifying early cognitive impairment in thesbe individuals.CONTEXTO: Comprometimento em funções não-motoras como perturbações em algumas funções executivas são também eventos comuns em pacientes com doença de Parkinson. OBJETIVO: Verificar as performances de pacientes com doença de Parkinson em atividades que requerem habilidades visuo-construtivas e visuo-espaciais. MÉTODO: Pacientes idosos (n=30 nos estágios leve ou moderado da doença de Parkinson foram estudados. O diagnóstico da condição clínica foi realizado por meio de: unified Parkinson's disease rating scale (56,28; SD=33,48, Hoehn e Yahr (2,2; SD=0,83, Schwab e England (78,93%, teste do desenho do relógio (7,36; SD=2,51, e mini-exame do estado mental (26,48; SD=10,11. A correlação de Pearson e a análise de regressão múltipla foram empregadas na análise estatística. RESULTADOS: Os pacientes apresentaram deterioração nas habilidades vísuo-espaciais e visuoconstrutivas. CONCLUSÃO: O teste do desenho do relógio provou ser uma ferramenta útil e preditiva para

  12. Expressões nominais referenciais em narrativas infantis: funções cognitivodiscursivas envolvidas na construção de objetos-de-discurso

    Directory of Open Access Journals (Sweden)

    Marcela Regina Vasconcelos da Silva

    2012-11-01

    Full Text Available Neste artigo, analisamos as funções cognitivo-discursivas das expressõesnominais referenciais utilizadas em textos narrativos produzidos porestudantes do Ensino Fundamental. Para tanto, adotamos a posturateórica de acordo com a qual a língua é algo que se constituidialogicamente, no processo da interação, de modo que o texto seconfigura como o próprio lugar da interação e da constituição dossujeitos. Consequentemente, a língua não pode ser entendida comotransparente, visto que não reflete o real; os objetos construídos noprocesso de discursivização reelaboram, de acordo com ainterpretação e a percepção dos sujeitos, os dados do real. Portanto,a atividade de referenciação realiza um processo de construção eordenação da realidade, o que justifica a importância de analisarsociocognitivamente as funções envolvidas na realização dessaatividade.

  13. [Entering the Dawn of a New Life: A Discussion of Life for Survivors of the Formosa Fun Coast Water Park Explosion].

    Science.gov (United States)

    Wen, Hui-Min

    2016-02-01

    A dust explosion at the Formosa Fun Coast water park in Taiwan caused nearly 500 burn injury cases. One hundred of these cases involved burns over more than 20% of the total body surface area. This tragedy inundated hospitals across northern Taiwan with an unprecedented number of burn patients. Significant manpower and medical resources were targeted on related resuscitation and treatment efforts, with support and assistance provided by agencies and organizations nationwide. Most of the burn patients were young people in their teens and twenties, whose severe burns posed the greatest threat and challenge to their lives so far. Furthermore, their experience presented major psychosocial and physical health challenges. Patients received an array of clinical treatments such as debridement, skin grafting, dressing, and rehabilitation. Debilitating pain, skin damage, changes to body image, physical disabilities, helplessness, sadness, and anxiety have not only deeply affected the patients physically and psychologically but also created significant life stresses for their family members / companions, which requires counseling in order to facilitate emotional healing. Although burn patients gradually recover as they pass through the acute, recovery, and rehabilitation phases, they will face the challenges of lifelong rehabilitation after discharge. I hope that these young victims will take courage and be brave and strong in dealing with the difficulties and challenges of daily life and will embrace the future with hope as they enter the dawn of their new life.

  14. Psychiatric worker and family members: pathways towards co-operation networks within psychiatric assistance services

    Directory of Open Access Journals (Sweden)

    Silvia Carbone

    2014-03-01

    Full Text Available The family’s role in patient care was greatly altered by Law 180. This law, introduced in Italy in 1978, led to a gradual phasing out of custodial treatment for psychiatric patients. This different mindset, which views the family as an alternative to institutionalization, leads to it being seen as an essential entity in the setting up of community service dynamics. We interviewed health professionals in order to understand obstacles of collaboration between family members and mental health care workers. The goal was to uncover actions that promote collaboration and help build alliances between families and psychiatric workers. Results showed that health professionals view the family as a therapeutic resource. Despite this view, family members were rarely included in patient treatment. The reasons is: the structures have a theoretical orientation of collaboration with the family but, for nurses not are organized a few meeting spaces with family members. Services should create moments, such as multi-family groups or groups of information, managed by nurses and not only by doctors. These occasions it might facilitate the knowledge between professionals and family members.

  15. Sales promotion strategies and youth drinking in Australia.

    Science.gov (United States)

    Pettigrew, Simone; Biagioni, Nicole; Jones, Sandra C; Daube, Mike; Kirby, Gary; Stafford, Julia; Chikritzhs, Tanya

    2015-09-01

    This study employed an exploratory approach to generate detailed information about how in-store shopping experiences and exposure to sales promotion activities feature in the alcohol choices of Australian 18-21 year old drinkers. The qualitative methods of interviews, focus groups, and emailed narratives were used during 2014 to collect relevant data. The findings suggest that young drinkers' in-store shopping experiences and exposure to sales promotions influence the type, range, and quantity of alcohol purchased. In particular, the role of sales staff can be critical in increasing the amount of alcohol purchased by drawing drinkers' attention to and encouraging their participation in sales promotions. There thus appears to be an important interaction between promotional practices and young drinkers purchasing substantially larger quantities of alcohol than originally intended. Such practices need review in light of the high risk of alcohol-related harm experienced by many members of this age group. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. The Members of the Agency

    International Nuclear Information System (INIS)

    2003-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.58) is Kyrgyzstan, which deposited the instrument of acceptance of the Statute on 10 September 2003. The list shows the dates on which the present 137 Member States became Members

  17. Identification and Characterization of 30 K Protein Genes Found in Bombyx mori (Lepidoptera: Bombycidae) Transcriptome

    Science.gov (United States)

    Shi, Xiao-Feng; Li, Yi-Nü; Yi, Yong-Zhu; Xiao, Xing-Guo; Zhang, Zhi-Fang

    2015-01-01

    The 30 K proteins, the major group of hemolymph proteins in the silkworm, Bombyx mori (Lepidoptera: Bombycidae), are structurally related with molecular masses of ∼30 kDa and are involved in various physiological processes, e.g., energy storage, embryonic development, and immune responses. For this report, known 30 K protein gene sequences were used as Blastn queries against sequences in the B. mori transcriptome (SilkTransDB). Twenty-nine cDNAs (Bm30K-1–29) were retrieved, including four being previously unidentified in the Lipoprotein_11 family. The genomic structures of the 29 genes were analyzed and they were mapped to their corresponding chromosomes. Furthermore, phylogenetic analysis revealed that the 29 genes encode three types of 30 K proteins. The members increased in each type is mainly a result of gene duplication with the appearance of each type preceding the differentiation of each species included in the tree. Real-Time Quantitative Polymerase Chain Reaction (Q-PCR) confirmed that the genes could be expressed, and that the three types have different temporal expression patterns. Proteins from the hemolymph was separated by SDS-PAGE, and those with molecular mass of ∼30 kDa were isolated and identified by mass spectrometry sequencing in combination with searches of various databases containing B. mori 30K protein sequences. Of the 34 proteins identified, 13 are members of the 30 K protein family, with one that had not been found in the SilkTransDB, although it had been found in the B. mori genome. Taken together, our results indicate that the 30 K protein family contains many members with various functions. Other methods will be required to find more members of the family. PMID:26078299

  18. Efeito do transplante renal na morfologia e função cardíaca

    OpenAIRE

    Souza,Francival Leite de; Monteiro Junior,Francisco das Chagas; Salgado Filho,Natalino

    2012-01-01

    O envolvimento cardíaco é muito frequente nos portadores de doença renal crônica em diálise. O transplante renal resulta em redução da morbidade e mortalidade em relação aos pacientes em diálise. O objetivo desta revisão foi abordar o efeito do transplante renal na estrutura e função cardíaca avaliada pela ecodopplercardiografia. Desde a década de 1980, os estudos já demonstravam tendência à melhora nos parâmetros cardíacos após o transplante renal. Com a melhora dos métodos de imagens ao eco...

  19. The Tucana/Horologium, Columba, AB Doradus, and Argus Associations: New Members and Dusty Debris Disks

    Science.gov (United States)

    Zuckerman, B.; Rhee, Joseph H.; Song, Inseok; Bessell, M. S.

    2011-05-01

    We propose 35 star systems within ~70 pc of Earth as newly identified members of nearby young stellar kinematic groups; these identifications include the first A- and late-B-type members of the AB Doradus moving group and field Argus Association. All but one of the 35 systems contain a bright solar- or earlier-type star that should make an excellent target for the next generation of adaptive optics (AO) imaging systems on large telescopes. AO imaging has revealed four massive planets in orbit around the λ Boo star HR 8799. Initially, the planets were of uncertain mass due in large part to the uncertain age of the star. We find that HR 8799 is a likely member of the ~30 Myr old Columba Association, implying planet masses ~6 times that of Jupiter. We consider Spitzer Space Telescope MIPS photometry of stars in the ~30 Myr old Tucana/Horologium and Columba Associations, the ~40 Myr old field Argus Association, and the ~70 Myr old AB Doradus moving group. The percentage of stars in these young stellar groups that display excess emission above the stellar photosphere at 24 and 70 μm wavelengths—indicative of the presence of a dusty debris disk—is compared with corresponding percentages for members of 11 open clusters and stellar associations with ages between 8 and 750 Myr, thus elucidating the decay of debris disks with time.

  20. Thermal effects in concrete members

    International Nuclear Information System (INIS)

    Kar, A.K.

    1977-01-01

    When subjected to temperature changes and restrained from free movement, a member develops stresses. Restrained members are sometimes assumed to act independently of other members. A method of analysis and design for thermal stresses in such members is provided. The method of analysis, based on the ultimate strength concept, greatly reduces the computational efforts for determining thermal effects in concrete members. Available charts and tables and the recommendations given herein simplify the design. (Auth.)

  1. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.67) is Cambodia which deposited its Instrument of Acceptance of the Statute on 23 November 2009. The Attachment hereto shows the dates on which the present 151 Member States became Members [fr

  2. The Members of the Agency

    International Nuclear Information System (INIS)

    2007-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.63) is Palau which deposited its Instrument of Acceptance of the Statute on 2 March 2007. The Attachment hereto shows the dates on which the present 144 Member States became Members

  3. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.67) is Cambodia which deposited its Instrument of Acceptance of the Statute on 23 November 2009. The Attachment hereto shows the dates on which the present 151 Member States became Members

  4. The Members of the Agency

    International Nuclear Information System (INIS)

    2008-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.64) is Nepal which deposited its Instrument of Acceptance of the Statute on 8 July 2008. The Attachment hereto shows the dates on which the present 145 Member States became Members

  5. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.67) is Cambodia which deposited its Instrument of Acceptance of the Statute on 23 November 2009. The Attachment hereto shows the dates on which the present 151 Member States became Members [ru

  6. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.67) is Cambodia which deposited its Instrument of Acceptance of the Statute on 23 November 2009. The Attachment hereto shows the dates on which the present 151 Member States became Members [es

  7. The Members of the Agency

    International Nuclear Information System (INIS)

    2006-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.60) is Chad, which deposited the instrument of acceptance of the Statute on 2 November 2005. The Attachment hereto shows the dates on which the present 139 Member States became Members

  8. The journal of undergraduate neuroscience education: history, challenges, and future developments.

    Science.gov (United States)

    Dunbar, Gary L; Lom, Barbara; Grisham, William; Ramirez, Julio J

    2009-01-01

    The 'JUNE and You' sessions presented at the July 2008 Undergraduate Neuroscience Education workshop, sponsored jointly by Faculty for Undergraduate Neuroscience (FUN) and Project Kaleidoscope (PKAL), featured background information about the history and mission of the Journal of Undergraduate Neuroscience Education (JUNE), followed by an informative discussion about the challenges facing JUNE, including new ideas for future developments. This article will highlight some of the information and ideas generated and shared at this conference. Critical discussion points included the need to keep members of FUN actively engaged in submitting and reviewing articles for JUNE. Ways in which authors, reviewers, and interested faculty members could best help in promoting the mission and vision of JUNE were discussed. Concerns about recent hackings into the JUNE website were also raised, and possible solutions and measures that can be taken to minimize this in the future were discussed. In addition, ideas for expanding the role of JUNE to provide a forum to evaluate new and emerging website information that is pertinent to undergraduate neuroscience education was discussed. Ideas for future developments of JUNE included revolving postings of articles as they are accepted, providing links to several related websites, and allowing updates for articles that have been previously published in JUNE. Finally, ideas for maintaining and expanding JUNE's stature as the resource for undergraduate neuroscience education included ensuring that JUNE is listed on important search vehicles, such as PubMed.

  9. An upstream open reading frame represses expression of Lc, a member of the R/B family of maize transcriptional activators

    Energy Technology Data Exchange (ETDEWEB)

    Damiani, R.D. Jr.; Wessler, S.R. (Univ. of Georgia, Athens, GA (United States))

    1993-09-01

    The R/B genes of maize encode a family of basic helix-loop-helix proteins that determine where and when the anthocyanin-pigment pathway will be expressed in the plant. Previous studies showed that allelic diversity among family members reflects differences in gene expression, specifically in transcription initiation. The authors present evidence that the R gene Lc is under translational control. They demonstrate that the 235-nt transcript leader of Lc represses expression 25- to 30-fold in an in vivo assay. Repression is mediated by the presence in cis of a 38-codon upstream open reading frame. Furthermore, the coding capacity of the upstream open reading frame influences the magnitude of repression. It is proposed that translational control does not contribute to tissue specificity but prevents overexpression of the Lc protein. The diversity of promoter and 5' untranslated leader sequences among the R/B genes provides an opportunity to study the coevolution of transcriptional and translational mechanisms of gene regulation. 36 refs., 5 figs.

  10. Does health promotion need a Code of Ethics? Results from an IUHPE mixed method survey.

    Science.gov (United States)

    Bull, Torill; Riggs, Elisha; Nchogu, Sussy N

    2012-09-01

    Health promotion is an ethically challenging field involving constant reflection of values across multiple cultures of what is regarded as good and bad health promotion practice. While many disciplines are guided by a Code of Ethics (CoE) no such guide is available to health promoters. The International Union for Health Promotion and Education (IUHPE) has been nominated as a suitable candidate for developing such a code. It is within this context that the IUHPE Student and Early Career Network (ISECN), through its Ethics Working Group, has taken up the challenge of preparing the foundations for a CoE for health promotion. An online survey comprising open and closed-answer questions was used to gather the opinions of IUHPE members regarding the need for a CoE for health promotion. The quantitative data were calculated with descriptive analyses. A thematic analysis approach was used to analyze and interpret the qualitative data. IUHPE members (n = 236) from all global regions responded to the survey. The majority (52%) of the respondents had 11 years' experience or more in the field of health promotion. Ethical dilemmas were commonly encountered. The need for a CoE for health promotion was expressed by 83% of respondents. Respondents also offered their views of possibilities, ideas and challenges regarding the development of a CoE for health promotion. Considering that health promoters encounter ethical dilemmas frequently in their practice, this study reinforces the need to develop a CoE for the field. The recommendations from the survey provide a good basis for future work to develop such a code.

  11. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.65) is the Sultanate of Oman which deposited its Instrument of Acceptance of the Statute on 5 February 2009. The Attachment hereto shows the dates on which the present 146 Member States became Members

  12. MicroRNA-125 family members exert a similar role in the regulation of murine hematopoiesis.

    Science.gov (United States)

    Wojtowicz, Edyta E; Walasek, Marta A; Broekhuis, Mathilde J C; Weersing, Ellen; Ritsema, Martha; Ausema, Albertina; Bystrykh, Leonid V; de Haan, Gerald

    2014-10-01

    MicroRNAs (miRNAs) are crucial for proper functioning of hematopoietic stem and progenitor cells (HSPCs). Members of the miRNA-125 family (consisting of miR-125a, miR-125b1, and miR-125b2) are known to confer a proliferative advantage on cells upon overexpression, to decrease the rate of apoptosis by targeting proapoptotic genes, and to promote differentiation toward the myeloid lineage in mice. However, many distinct biological effects of the three miR-125 species have been reported as well. In the current study, we set out to assess whether the three miRNA-125s that carry identical seed sequences could be functionally different. Our data show that overexpression of each of the three miR-125 family members preserves HSPCs in a primitive state in vitro, results in a competitive advantage upon serial transplantation, and promotes skewing toward the myeloid lineage. All miR-125 family members decreased the pool of phenotypically defined Lin(-)Sca(+)Kit(+)CD48(-)CD150(+) long-term hematopoietic stem cells, simultaneously increasing the self-renewal activity upon secondary transplantation. The downregulation of miR-125s in hematopoietic stem cells abolishes these effects and impairs long-term contribution to blood cell production. The introduction of a point mutation within the miRNA-125 seed sequence abolishes all abovementioned effects and leads to the restoration of normal hematopoiesis. Our results show that all miR-125 family members are similar in function, they likely operate in a seed-sequence-dependent manner, and they induce a highly comparable hematopoietic phenotype. Copyright © 2014 ISEH - International Society for Experimental Hematology. Published by Elsevier Inc. All rights reserved.

  13. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.65) is the Sultanate of Oman which deposited its Instrument of Acceptance of the Statute on 5 February 2009. The Attachment hereto shows the dates on which the present 146 Member States became Members [fr

  14. The Members of the Agency

    International Nuclear Information System (INIS)

    2005-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.59) is the Islamic Republic of Mauritania, which deposited the instrument of acceptance of the Statute on 23 November 2004. The Attachment hereto shows the dates on which the present 138 Member States became Members

  15. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.65) is the Sultanate of Oman which deposited its Instrument of Acceptance of the Statute on 5 February 2009. The Attachment hereto shows the dates on which the present 146 Member States became Members [es

  16. ARL and Association 3.0: Ten Management Challenges

    Science.gov (United States)

    Funk, Carla J.

    2009-01-01

    Association management in today's "association 3.0" environment presents some new challenges and new perspectives on old ones. This paper summarizes 10 such challenges including collaboration, diversity, innovation, transparency, financial stability, member benefits, knowledge-based decision-making, a demand-driven association model, pro-activity…

  17. Implementation of evidence-based medicine in a health promotion teaching block for Thai medical students.

    Science.gov (United States)

    Liabsuetrakul, Tippawan; Suntharasaj, Thitima; Sangsupawanich, Pasuree; Kongkamol, Chanon; Pornsawat, Panumad

    2017-12-01

    Evidence-based medicine (EBM) is well known in medical practice. Although health promotion (HP) is promoted worldwide, there is still some debate as to whether EBM is needed or useful in the teaching of health promotion. To assess the perceived usefulness of EBM in the teaching of HP among medical students and faculty members. A comparative study was conducted between two groups of fourth-year medical students in the academic year 2012 during the five-week Health Promotion Teaching Block at Prince of Songkla University, southern Thailand. A one-week EBM course was conducted with half the students in the first week of the block and the other half of the students in the last week of the block. All activities in the HP block were similar except for the different periods of the one-week of EBM teaching. The effect on knowledge, ability and perceived application of EBM in future practice was assessed by student self-evaluations before versus after taking the EBM course, and by faculty member evaluation of the students' end-of-block presentations. All evaluation items were rated from 1 (lowest) to 5 (highest). Data were analyzed using a t-test or Wilcoxon test, as appropriate. The students' self-evaluations of knowledge and ability on EBM between the two groups were similar. The perception that teaching EBM is beneficial in health promotion and future practice increased significantly ( phigher scores for the first group than the second group, although the rating differences were not at the level of significance. Ninety percent of the students believed that EBM was a useful addition to the teaching of HP. Medical students and faculty members perceived that EBM is useful in the HP context. Future studies to evaluate the effect of using evidence-based teaching for health promotion are needed.

  18. Administrative Circular No. 30 (Rev. 3) - “Financial benefits on taking up appointment and on termination of contract”

    CERN Multimedia

    2013-01-01

    Administrative Circular No. 30 (Rev. 3) entitled “Financial benefits on taking up appointment and on termination of contract”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 27 June 2013 and entering into force on 1 August 2013, is available on the intranet site of the Human Resources Department (see here).   Administrative Circular No. 30 (Rev. 3) is applicable to all members of the personnel. It cancels and replaces Administrative Circular No. 30 (Rev. 2/Corr.) entitled "Financial benefits on taking up appointment and on termination of contract” of September 2009. This circular was revised in order to implement the modifications introduced into the Staff Rules and Regulations in January 2013 relating to the introduction of the status of Associate Member States and new categories of associated members of the personnel. In particular, the notion of “Member State” in Annexe II (&a...

  19. O consumo de maconha na adolescência e as conseqüências nas funções cognitivas El consumo de marihuana en la adolescencia y sus consecuencias en las funciones The use of cannabis in adolescence and it's effects in the cognitive functions

    Directory of Open Access Journals (Sweden)

    Maisa dos Santos Rigoni

    2007-08-01

    Full Text Available Este estudo objetiva comparar o desempenho nas funções cognitivas de 30 usuários de maconha e de 30 não usuários. Os instrumentos usados foram uma entrevista estruturada; Screening Cognitivo (WISC-III e WAIS-III; WCST e Figuras Complexas de Rey. A amostra foi de 60 adolescentes, idades entre 14 e 17 anos, e escolaridade mínima de 5ª série do Ensino Fundamental. Observou-se que houve diferença estatisticamente significativa no desempenho dos dois grupos em todos os testes neuropsicológicos aplicados; no subteste Código e no WCST, o grupo de usuários denotou desempenho mais prejudicado. Concluiu-se que a maconha pode afetar funções cognitivas de adolescentes usuários.Este estudio tiene como objetivo el de comparar el desempeño en las funciones cognitivas de 30 usuarios de marihuana y de 30 no usuarios. Los instrumentos usados fueron una entrevista estructurada; Screening Cognitivo (WISC-III y WAIS-III; WCST y Figuras Complejas de Rey. La muestra fue de 60 adolescentes, con edad entre 14 y 17 años y escolaridad mínima de 5 º año de la educación primaria. Se observó que hubo diferencia estadísticamente significativa en el desempeño de los dos grupos en todos los testes neuropsicológicos aplicados; en el sub-test código y no WCST, el grupo de usuarios obtuvo desempeño más perjudicado. Se concluyó que la marihuana puede afectar funciones cognitivas de adolescentes usuarios.The objective of the study was to compare the cognitive function performance between a group of 30 cannabis users and a group of 30 non-users. The instruments used were a structured interview; Cognitive Screening (WISC - III and WAIS-III; WCST and Rey Complex Figure Test. The sample was 60 adolescents, aged from 14 to 17 from 5th grade on. The results showed that was statistically significant difference in the performance of the two groups in every neuropsychological test applied, and, in the Digit Symbol and in the WCST subtests, the users' group showed

  20. A Social Network Family-Focused Intervention to Promote Smoking Cessation in Chinese and Vietnamese American Male Smokers: A Feasibility Study.

    Science.gov (United States)

    Tsoh, Janice Y; Burke, Nancy J; Gildengorin, Ginny; Wong, Ching; Le, Khanh; Nguyen, Anthony; Chan, Joanne L; Sun, Angela; McPhee, Stephen J; Nguyen, Tung T

    2015-08-01

    Smoking prevalence is high among limited English-proficient Chinese and Vietnamese American men, who are frequently unmotivated to quit and who underutilize smoking cessation resources. This study applied lay health worker outreach to leverage peer and family networks to promote smoking cessation among these men. We integrated qualitative formative research findings and Social Network Theory to develop a social-network family-focused intervention. In a pilot single-group trial, 15 lay health workers recruited 96 dyads (N = 192, 75% Vietnamese) of Chinese or Vietnamese male daily smokers and their family members and delivered the intervention consisting of two small group education sessions and two individual telephone calls over 2 months. At baseline, 42% of smokers were at precontemplation. At 3 months following the initiation of the intervention, 7-day and 30-day point prevalence smoking abstinence rates as reported by smokers and independently corroborated by family members were 30% and 24%, respectively. Utilization of smoking cessation resources (medication, quitline, physician's advice) increased from 2% to 60% (P Vietnamese smokers appears to be acceptable, feasible, and potentially efficacious. Findings warrant evaluation of long-term efficacy of the intervention in a larger scale randomized controlled trial. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Government-Driven Participation and Collective Intelligence: A Case of the Government 3.0 Initiative in Korea

    Directory of Open Access Journals (Sweden)

    Taewoo Nam

    2016-10-01

    Full Text Available The Park Geun-hye Administration of Korea (2013–2017 aims to increase the level of transparency and citizen trust in government through the Government 3.0 initiative. This new initiative for public sector innovation encourages citizen-government collaboration and collective intelligence, thereby improving the quality of policy-making and implementation and solving public problems in a new way. However, the national initiative that identifies collective intelligence and citizen-government collaboration alike fails to understand what the wisdom of crowds genuinely means. Collective intelligence is not a magic bullet to solve public problems, which are called “wicked problems”. Collective deliberation over public issues often brings pain and patience, rather than fun and joy. It is not so easy that the public finds the best solution for soothing public problems through collective deliberation. The Government 3.0 initiative does not pay much attention to difficulties in gathering scattered wisdom, but rather highlights uncertain opportunities created by collective interactions and communications. This study deeply discusses the weaknesses in the logic of, and approach to, collective intelligence underlying the Government 3.0 initiative in Korea and the overall influence of the national initiative on participatory democracy.

  2. Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

    DEFF Research Database (Denmark)

    Rohde, Mikkel; Daugaard, Mads; Jensen, Mette Hartvig

    2005-01-01

    Whereas the stress-inducible heat-shock protein 70 (Hsp70) has gained plenty of attention as a putative target for tumor therapy, little is known about the role of other Hsp70 proteins in cancer. Here we present the first thorough analysis of the expression and function of the cytosolic Hsp70...... proteins in human cancer cells and identify Hsp70-2, a protein essential for spermatogenesis, as an important regulator of cancer cell growth. Targeted knock-down of the individual family members by RNA interference revealed that both Hsp70 and Hsp70-2 were required for cancer cell growth, whereas...

  3. Reciprocity Outperforms Conformity to Promote Cooperation.

    Science.gov (United States)

    Romano, Angelo; Balliet, Daniel

    2017-10-01

    Evolutionary psychologists have proposed two processes that could give rise to the pervasiveness of human cooperation observed among individuals who are not genetically related: reciprocity and conformity. We tested whether reciprocity outperformed conformity in promoting cooperation, especially when these psychological processes would promote a different cooperative or noncooperative response. To do so, across three studies, we observed participants' cooperation with a partner after learning (a) that their partner had behaved cooperatively (or not) on several previous trials and (b) that their group members had behaved cooperatively (or not) on several previous trials with that same partner. Although we found that people both reciprocate and conform, reciprocity has a stronger influence on cooperation. Moreover, we found that conformity can be partly explained by a concern about one's reputation-a finding that supports a reciprocity framework.

  4. A estimulação cardíaca convencional é prejudicial em pacientes com função ventricular normal?

    Directory of Open Access Journals (Sweden)

    Luiz Antonio Batista de Sá

    2013-12-01

    Full Text Available FUNDAMENTO: A estimulação de ventrículo direito pode ser deletéria em pacientes com disfunção ventricular, porém, em pacientes com função normal, o impacto desta estimulação desencadeando disfunção ventricular clinicamente relevante não é completamente estabelecido. OBJETIVOS: Avaliar a evolução clínica, ecocardiográfica e laboratorial de pacientes, com função ventricular esquerdapreviamente normal, submetidos a implante de marca-passo. MÉTODO: Estudo observacional transversal em que foram acompanhados de forma prospectiva 20 pacientes submetidos a implante de marca-passo com os seguintes critérios de inclusão: função ventricular esquerda normal definida pelo ecocardiograma e estimulação ventricular superior a 90%. Foram avaliados: classe funcional (CF (New York Heart Association, teste de caminhada de 6 minutos (TC6, dosagem do hormônio natriurético tipo B (BNP, avaliação ecocardiográfica (convencional e parâmetros de dessincronismo e questionário de qualidade de vida (QV (SF-36. A avaliação foi feita com dez dias (t1, quatro meses (t2, oito meses (t3, 12 meses (t4 e 24 meses (t5. RESULTADOS: Os parâmetros ecocardiográficos convencionais e de dessincronismo não apresentaram variação estatística significante ao longo do tempo. O TC6, a CF e a dosagem de BNP apresentaram piora ao final dos dois anos. A QV teve melhora inicial e piora ao final dos dois anos. CONCLUSÃO: O implante de marca-passo convencional foi associado à piora da classe funcional, piora do teste de caminhada, aumento da dosagem de BNP, aumento da duração do QRS e piora em alguns domínios da QV ao final de dois anos. Não houve alterações nas medidas ecocardiográficas (convencionais e medidas de assincronia.

  5. It’s All Fun and Games until Someone Learns Something: Assessing the Learning Outcomes of Two Educational Games

    Directory of Open Access Journals (Sweden)

    Steven Wise

    2009-12-01

    Full Text Available Objective – To determine whether educational games can be designed that are both fun and effective in improving information seeking skills. Methods – Two skills that are known to be particularly difficult for students taking a required information literacy test were identified. These skills are the ability to identify citations and the ability to search databases with keywords. Educational games were designed to address these two skills. The first game, Citation Tic Tac Toe, placed commonly used bibliographic citations into a tick tac toe style grid. Students were required to play the Tic Tac Toe game and subsequently given citation identification exercises. The second game arranged key concepts related to search phrases in a Magnetic Keyword interface. Students were observed searching databases before and after playing the Magnetic Keyword game and their pre‐ and post‐play searches were analyzed.Results – Students who played the Tic Tac Toe game improved more from pretest to posttest than students who only took an online tutorial. In addition, students who played the Magnetic Keyword game demonstrated quicker database searching for their topics and expressed increased satisfaction with their results. Conclusions – Games can be created which have measurable educational outcomes and are fun. It is important, however, to establish the educational objective prior to beginning game design.

  6. Pilot project - Promoting protection of the right to housing

    DEFF Research Database (Denmark)

    This study was undertaken for the European Commission Directorate-General for Employment, Social Affairs & Inclusion as part of the ‘Promoting protection of the right to housing - Homelessness prevention in the context of evictions’ pilot project. The key objectives of the research were: - to pro......This study was undertaken for the European Commission Directorate-General for Employment, Social Affairs & Inclusion as part of the ‘Promoting protection of the right to housing - Homelessness prevention in the context of evictions’ pilot project. The key objectives of the research were......: - to provide an overview and analysis of available data and trends regarding housing evictions between 2010 and 2013 across the 28 EU Member States; - to establish the reasons for and impacts of eviction, in particular the relative importance of eviction as a pathway into homelessness; - to analyse...... the legislative and regulatory framework and the availability, effectiveness and cost-efficiency of measures designed to prevent and tackle evictions and enable early interventions; - to suggest ways to improve data collection and the monitoring of evictions in the Member States, identifying the most important...

  7. The Members of the Agency

    International Nuclear Information System (INIS)

    2006-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.61) are Belize, Mozambique and Malawi, which deposited their Instruments of Acceptance of the Statute on 31 March 2006, 18 September 2006 and 2 October 2006 respectively. The Attachment hereto shows the dates on which the present 142 Member States became Members [fr

  8. The Members of the Agency

    International Nuclear Information System (INIS)

    2006-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.61) are Belize, Mozambique and Malawi, which deposited their Instruments of Acceptance of the Statute on 31 March 2006, 18 September 2006 and 2 October 2006 respectively. The Attachment hereto shows the dates on which the present 142 Member States became Members

  9. Health promotion and schizophrenia: the year 2000 and beyond.

    Science.gov (United States)

    O'Brien, S M

    1998-01-01

    The health promotion needs of persons with schizophrenia have not been emphasized as a result of historical stigma, the effort required to stabilize symptoms, the relapsing nature of the disease, and the helplessness felt by caregivers. Family members and individuals with schizophrenia experience shame, grief, guilt, fear, and isolation, all of which render them less able to be proactive. Health promotion strategies that change attitudes, build self-esteem, increase insight into the illness, modify behavior, provide sources of income and access to medical care, and support companionship are necessary while research efforts seek a cure for this historically misunderstood illness.

  10. Effectiveness of physical activity promotion in blood pressure and blood sugar reduction: A community-based intervention study in rural south India

    Directory of Open Access Journals (Sweden)

    Subitha Lakshminarayanan

    2012-01-01

    Full Text Available Context: Physical activity of moderate intensity for 30 minutes a day, on most days substantially reduces the risk of many chronic diseases. Aim: To assess the effect of regular physical activity on blood pressure and blood sugar levels in a rural Indian community Settings and Design: This community-based study was carried out in Periakattupalayam and Rangareddipalayam in south India, with 485 subjects, aged 20 to 49 years. Materials and Methods: The study was done in five phases: Awareness campaign, baseline assessment of participants, intervention phase (10 weeks, interim, and final assessment. Physical activity of moderate intensity (brisk walking for 30 minutes on four days / week was promoted by forming 30 small walking groups, in a home-based setting, with professional supervision. Village leaders and Self-Help Group members were the resource people for the promotion of physical activity. Statistical Analysis: Analysis was done by using paired ′t′ test; the ′Intention-to-Treat′ approach was utilized for the interpretation of the findings of the study. Results: Of the 485 subjects, 265 (54.6% complied with walking on more than four days / week, while 156 (32.2% walked on one to four days / week, and 64 (13.2% dropped out during the intervention period. This study has shown that a 10-week intervention to promote physical activity was effective in significantly decreasing the population′s BP by 1.56 / 0.74 mm Hg, fasting blood sugar levels by 2.82 mg%, body weight by 0.17 kg, and BMI by 0.06 kg / m 2 . Conclusions: This study has proved the functional feasibility of enabling people to undertake physical activity in a rural Indian community, and the effectiveness of using physical activity, to significantly reduce the population′s mean BP and blood sugar levels.

  11. Satisfaction of Iranian Medical Universities’ faculty members towards holding Shahid Motahari Annual Educational Festival

    Science.gov (United States)

    HOSSEINI, SEYYED NASROLLAH; MOHSENI BAND PEY, ANOSHIRAVAN; HOSSEINI, SEYYED ALI; KARAMI MATIN, BEHZAD; MIRZAEI ALAVIJEH, MEHDI; JALILIAN, FARZAD

    2015-01-01

    Introduction Shahid Motahari Annual Educational Festival aims to improve the quality of medical education in the Islamic Republic of Iran, and has held since 2008. The present study was performed to determine the satisfaction level of Iranian medical universities’ faculty members about holding Shahid Motahari Annual Educational Festival during the past six years, from 2008 to 2014. Methods This cross-sectional study was conducted on 473 faculty members (FMs) including deputies and educational administrators, managers, and faculty members of medical education development centers, members of scientific committees, and faculty members who participated in Shahid Motahari Festival from 42 medical sciences universities in Iran. Data collection instruments were two reliable and valid questionnaires on the background and also participants’ satisfaction towards Shahid Motahari Educational Festival. Data were analyzed using SPSS Software, version 14. Results Among all participants, 30 FMs (6.3%) were educational deputies, 36 FMs (7.6%) managers of medical education development centers, 226 FMs (56.2%) members of scientific committees, 29 FMs (6.1%) members of the national committees, 343 FMs (27.5%) attendees, and 264 FMs (55.8%) had participated for retraining. The total satisfaction level of the participants was 73.3% which shows a good satisfaction level. Conclusion The results identified the main important strength points such as “proposals’ review process at the country level” and weakness points such as “organizing the festival”. PMID:26457313

  12. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.66) are Bahrain, Burundi, Congo and Lesotho which deposited their Instruments of Acceptance of the Statute on 23 June 2009, 24 June 2009, 15 July 2009 and 13 July 2009, respectively. The Attachment hereto shows the dates on which the present 150 Member States became Members [fr

  13. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.66) are Bahrain, Burundi, Congo and Lesotho which deposited their Instruments of Acceptance of the Statute on 23 June 2009, 24 June 2009, 15 July 2009 and 13 July 2009, respectively. The Attachment hereto shows the dates on which the present 150 Member States became Members

  14. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.66) are Bahrain, Burundi, Congo and Lesotho which deposited their Instruments of Acceptance of the Statute on 23 June 2009, 24 June 2009, 15 July 2009 and 13 July 2009, respectively. The Attachment hereto shows the dates on which the present 150 Member States became Members [ru

  15. The Members of the Agency

    International Nuclear Information System (INIS)

    2009-01-01

    The new Members since the last list of Member States was issued (INFCIRC/2/Rev.66) are Bahrain, Burundi, Congo and Lesotho which deposited their Instruments of Acceptance of the Statute on 23 June 2009, 24 June 2009, 15 July 2009 and 13 July 2009, respectively. The Attachment hereto shows the dates on which the present 150 Member States became Members [es

  16. Elections of members to the Governing Board of the Pension Fund

    CERN Multimedia

    2003-01-01

    This year, one member and one alternate are to be elected. The candidate who obtains most votes will be elected member and the other candidate will be her/his alternate. Timetable (extract) : Monday 3 November 2003Second publication of the candidates' publicity in the Bulletin (see thereafter) and distribution of the ballot papers at CERN. Monday 24 November 2003Voting closes at 12 hrs. Counting of votes from 14.30 hrs. Tuesday 25 November 2003 Forwarding of results to the Communications Section for publication in the Bulletin of 1 December. This candidature has been duly registered and is hereby presented in accordance with paragraph 6.h of the Regulations for Elections to the Governing Board of the Pension Fund. Candidate:Name: RANJARD First name: FlorenceHaving been a member of the Governing Board of the Pension Fund since 1983 as Guy Maurin's alternate, I am standing for a further 3-year term of office. This year Guy Maurin will not be a candidate, however we should pursue the active management of the as...

  17. 7 CFR 983.42 - Initial members and nomination of successor members.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF... alternate is selected shall serve in place of that member on the committee, and shall have and be able to... members of the committee shall serve for terms of two years: Provided, That four of the initially selected...

  18. Chemistry, Poetry, and Artistic Illustration: An Interdisciplinary Approach to Teaching and Promoting Chemistry

    Science.gov (United States)

    Furlan, Ping Y.; Kitson, Herbert; Andes, Cynthia

    2007-10-01

    This article describes a successful interdisciplinary collaboration among chemistry, humanities and English faculty members, who utilized poetry and artistic illustration to help students learn, appreciate, and enjoy chemistry. Students taking general chemistry classes were introduced to poetry writing and museum-type poster preparation during one class period. They were then encouraged to use their imagination and creativity to brainstorm and write chemistry poems or humors on the concepts and principles covered in the chemistry classes and artistically illustrate their original work on posters. The project, 2 3 months in length, was perceived by students as effective at helping them learn chemistry and express their understanding in a fun, personal, and creative way. The instructors found students listened to the directives because many posters were witty, clever, and eye-catching. They showed fresh use of language and revealed a good understanding of chemistry. The top posters were created by a mix of A-, B-, and C-level students. The fine art work, coupled with poetry, helped chemistry come alive on campus, providing an aesthetic presentation of materials that engaged the general viewer.

  19. Alterações morfológicas em traquéias de pacientes intubados em função do tempo de intubação

    Directory of Open Access Journals (Sweden)

    Barbosa Pedro Marco Karan

    2003-01-01

    Full Text Available Este é um estudo, de caráter analítico-descritivo, que teve como objetivo descrever as alterações morfológicas da traquéia de pacientes intubados com cânulas de alto volume residual e baixa pressão no "cuff", mantidos em ventilação mecânica com pressão intra -"cuff" menor que a capilar da traquéia (20 a 30 mmHg, em função do tempo de intubação. A população constou de 23 pacientes adultos, internados em uma UTI, intubados por períodos entre 27 a 317 horas, e que foram a óbito, necessitando de necropsia para identificação da causa mortis. As alterações encontradas limitaram-se apenas à mucosa da traquéia, atingindo somente o epitélio de revestimento e a lâmina própria, e o tempo de intubação foi um fator determinante do agravamento das lesões na parede traqueal.

  20. Promoter Motifs in NCLDVs: An Evolutionary Perspective

    Directory of Open Access Journals (Sweden)

    Graziele Pereira Oliveira

    2017-01-01

    Full Text Available For many years, gene expression in the three cellular domains has been studied in an attempt to discover sequences associated with the regulation of the transcription process. Some specific transcriptional features were described in viruses, although few studies have been devoted to understanding the evolutionary aspects related to the spread of promoter motifs through related viral families. The discovery of giant viruses and the proposition of the new viral order Megavirales that comprise a monophyletic group, named nucleo-cytoplasmic large DNA viruses (NCLDV, raised new questions in the field. Some putative promoter sequences have already been described for some NCLDV members, bringing new insights into the evolutionary history of these complex microorganisms. In this review, we summarize the main aspects of the transcription regulation process in the three domains of life, followed by a systematic description of what is currently known about promoter regions in several NCLDVs. We also discuss how the analysis of the promoter sequences could bring new ideas about the giant viruses’ evolution. Finally, considering a possible common ancestor for the NCLDV group, we discussed possible promoters’ evolutionary scenarios and propose the term “MEGA-box” to designate an ancestor promoter motif (‘TATATAAAATTGA’ that could be evolved gradually by nucleotides’ gain and loss and point mutations.

  1. Promoter Motifs in NCLDVs: An Evolutionary Perspective

    Science.gov (United States)

    Oliveira, Graziele Pereira; Andrade, Ana Cláudia dos Santos Pereira; Rodrigues, Rodrigo Araújo Lima; Arantes, Thalita Souza; Boratto, Paulo Victor Miranda; Silva, Ludmila Karen dos Santos; Dornas, Fábio Pio; Trindade, Giliane de Souza; Drumond, Betânia Paiva; La Scola, Bernard; Kroon, Erna Geessien; Abrahão, Jônatas Santos

    2017-01-01

    For many years, gene expression in the three cellular domains has been studied in an attempt to discover sequences associated with the regulation of the transcription process. Some specific transcriptional features were described in viruses, although few studies have been devoted to understanding the evolutionary aspects related to the spread of promoter motifs through related viral families. The discovery of giant viruses and the proposition of the new viral order Megavirales that comprise a monophyletic group, named nucleo-cytoplasmic large DNA viruses (NCLDV), raised new questions in the field. Some putative promoter sequences have already been described for some NCLDV members, bringing new insights into the evolutionary history of these complex microorganisms. In this review, we summarize the main aspects of the transcription regulation process in the three domains of life, followed by a systematic description of what is currently known about promoter regions in several NCLDVs. We also discuss how the analysis of the promoter sequences could bring new ideas about the giant viruses’ evolution. Finally, considering a possible common ancestor for the NCLDV group, we discussed possible promoters’ evolutionary scenarios and propose the term “MEGA-box” to designate an ancestor promoter motif (‘TATATAAAATTGA’) that could be evolved gradually by nucleotides’ gain and loss and point mutations. PMID:28117683

  2. Exploring the Mediating Effect of E-social Capital Between Community Members Interaction and Consumer Engagement

    OpenAIRE

    Yan Bingsheng; Li Lihua; Sun Hongtao

    2017-01-01

    This article explored the effect of instrumental interaction and relational interaction on consumer engagement (community engagement and brand engagement) among community members. The mediating effect of E-social capital was investigated as well. The research results showed that: both instrumental interaction and interpersonal interaction promote the formation of E-social capital (online trust and online reciprocity); online trust plays a partial mediating role between community interaction (...

  3. Challenges of Measuring a Faculty Member Activity in Medical Schools

    OpenAIRE

    Mohammadi, A; Mojtahedzadeh, R; Emami Razavi, S H

    2011-01-01

    Background One of the features of Mission Based Management is measuring the activities of faculty members and departments and their contributions to the school's mission. As it is important to assess the school's readiness for such a system, in this study we assessed the view points of Tehran Medical School's department chairs about faculty members’ activities. Methods We used focus group technique to identify participants' view points. We divided 30 department chairs into homogenous groups o...

  4. Comportamento agronômico de bananeira 'Prata-anã' em função do tipo de muda Agromic performance of 'Prata-anã' banana regarding to plant propagation method

    Directory of Open Access Journals (Sweden)

    Luiz Antonio Junqueira Teixeira

    2011-03-01

    Full Text Available Foi realizado um experimento de campo com bananeira 'Prata-anã', visando a avaliar o comportamento agronômico de plantas estabelecidas a partir de três tipos de mudas: convencional, micropropagadas em meio sólido e em meio líquido. A área experimental foi instalada no município de Cristais Paulista-SP (20º23'S; 47º30'W, cujo clima é caracterizado por verão chuvoso e inverno seco. Avaliaram-se o crescimento e a fenologia por meio de medidas periódicas de comprimento e diâmetro do pseudocaule das plantas até a emissão da inflorescência. A incidência de doenças (CMV e mal-do-panamá foi estimada visualmente em função da apresentação de sintomas característicos pelas plantas. As plantas originadas de mudas micropropagadas apresentaram crescimento e desenvolvimento iniciais mais vigorosos, maior precocidade e cachos mais leves do que aquelas estabelecidas com mudas convencionais. Não foram observadas diferenças significativas em relação à incidência de doenças e ao tamanho dos frutos produzidos, em função dos tipos de mudas.A field experiment with 'Prata-anã' banana was conducted to evaluate the agronomic performance of tissue culture-propagated plants in solid or liquid culture medium and conventionally propagated plants. The experiment was installed in Cristais Paulista (20º23'S; 47º30'W, Planalto Region of State of Sao Paulo (Brazil. This region is characterized by a summer rainy season and dry winter. Plant growth and phenology were assessed through periodic measurements of length and stem diameter of the plants until flowering. The incidence of diseases (CMV and Panama disease was estimated visually according to the presentation of symptoms by plants. The tissue culture-propagated-plants in solid or liquid medium showed initial growth and development more vigorous, precocious flowering and lighter bunches than those from conventionally propagated plants. There were no significant differences in the incidence of

  5. Toscana virus NSs protein promotes degradation of double-stranded RNA-dependent protein kinase.

    Science.gov (United States)

    Kalveram, Birte; Ikegami, Tetsuro

    2013-04-01

    Toscana virus (TOSV), which is transmitted by Phlebotomus spp. sandflies, is a major etiologic agent of aseptic meningitis and encephalitis in the Mediterranean. Like other members of the genus Phlebovirus of the family Bunyaviridae, TOSV encodes a nonstructural protein (NSs) in its small RNA segment. Although the NSs of Rift Valley fever virus (RVFV) has been identified as an important virulence factor, which suppresses host general transcription, inhibits transcription from the beta interferon promoter, and promotes the proteasomal degradation of double-stranded RNA-dependent protein kinase (PKR), little is known about the functions of NSs proteins encoded by less-pathogenic members of this genus. In this study we report that TOSV is able to downregulate PKR with similar efficiency as RVFV, while infection with the other phleboviruses-i.e., Punta Toro virus, sandfly fever Sicilian virus, or Frijoles virus-has no effect on cellular PKR levels. In contrast to RVFV, however, cellular transcription remains unaffected during TOSV infection. TOSV NSs protein promotes the proteasome-dependent downregulation of PKR and is able to interact with kinase-inactive PKR in infected cells.

  6. Importância da utilização de propriedades avaliadas em função da temperatura para a simulação computacional de cerâmicas refratárias

    Directory of Open Access Journals (Sweden)

    Akiyoshi M. M.

    2002-01-01

    Full Text Available Neste trabalho é apresentado um estudo sistemático sobre a influência da utilização de propriedades avaliadas em função da temperatura para suprir um programa de simulação computacional por elementos finitos (AEF visando à determinação dos perfis de temperatura e tensão em uma âncora refratária. Para tanto, foram avaliados em função da temperatura, a condutividade térmica (k, o calor específico (c, o coeficiente de expansão térmica linear (alfaL e o módulo elástico (E. Um planejamento fatorial 2u e a análise de variância (ANOVA foram utilizados para avaliar a influência das interações entre as propriedades determinadas em função da temperatura sobre os perfis de temperatura e tensão normal resultantes da simulação computacional. Este estudo reforça a necessidade da avaliação das propriedades em função da temperatura para se suprir um programa de simulação computacional, destacando-se a condutividade térmica e o calor específico para propiciar uma melhor obtenção do perfil de temperatura, e o coeficiente de expansão térmica linear (alfaL e o módulo elástico (E para a avaliação do perfil de tensões.

  7. THE TUCANA/HOROLOGIUM, COLUMBA, AB DORADUS, AND ARGUS ASSOCIATIONS: NEW MEMBERS AND DUSTY DEBRIS DISKS

    International Nuclear Information System (INIS)

    Zuckerman, B.; Rhee, Joseph H.; Song, Inseok; Bessell, M. S.

    2011-01-01

    We propose 35 star systems within ∼70 pc of Earth as newly identified members of nearby young stellar kinematic groups; these identifications include the first A- and late-B-type members of the AB Doradus moving group and field Argus Association. All but one of the 35 systems contain a bright solar- or earlier-type star that should make an excellent target for the next generation of adaptive optics (AO) imaging systems on large telescopes. AO imaging has revealed four massive planets in orbit around the λ Boo star HR 8799. Initially, the planets were of uncertain mass due in large part to the uncertain age of the star. We find that HR 8799 is a likely member of the ∼30 Myr old Columba Association, implying planet masses ∼6 times that of Jupiter. We consider Spitzer Space Telescope MIPS photometry of stars in the ∼30 Myr old Tucana/Horologium and Columba Associations, the ∼40 Myr old field Argus Association, and the ∼70 Myr old AB Doradus moving group. The percentage of stars in these young stellar groups that display excess emission above the stellar photosphere at 24 and 70 μm wavelengths-indicative of the presence of a dusty debris disk-is compared with corresponding percentages for members of 11 open clusters and stellar associations with ages between 8 and 750 Myr, thus elucidating the decay of debris disks with time.

  8. The interaction of parsing rules and argument – Predicate constructions: implications for the structure of the Grammaticon in FunGramKB

    Directory of Open Access Journals (Sweden)

    María del Carmen Fumero Pérez

    2017-07-01

    Full Text Available The Functional Grammar Knowledge Base (FunGramKB, (Periñán-Pascual and Arcas-Túnez 2010 is a multipurpose lexico-conceptual knowledge base designed to be used in different Natural Language Processing (NLP tasks. It is complemented with the ARTEMIS (Automatically Representing Text Meaning via an Interlingua–based System application, a parsing device linguistically grounded on Role and Reference Grammar (RRG that transduces natural language fragments into their corresponding grammatical and semantic structures. This paper unveils the different phases involved in its parsing routine, paying special attention to the treatment of argumental constructions. As an illustrative case, we will follow all the steps necessary to effectively parse a For-Benefactive structure within ARTEMIS. This methodology will reveal the necessity to distinguish between Kernel constructs and L1-constructions, since the latter involve a modification of the lexical template of the verb. Our definition of L1-constructions leads to the reorganization of the catalogue of FunGramKB L1-constructions, formerly based on Levin’s (1993 alternations. Accordingly, a rearrangement of the internal configuration of the L1-Constructicon within the Grammaticon is proposed.

  9. Análise crítica do conceito de função social da propriedade urbana mediante estudo de caso na bacia hidrográfica do Guarapiranga - SP

    Directory of Open Access Journals (Sweden)

    Ana Luiza Silva Spínola Krings

    2006-12-01

    Full Text Available O direito de propriedade, antigamente considerado ilimitado, foi gradualmente vinculado a uma finalidade social e ambiental. Os objetivos deste texto são: estudar o conceito, conteúdo, limites e possibilidade de aplicação prática do princípio da função social da propriedade urbana; apresentar os principais diplomas legais; constatar se o conceito abrange a proteção ambiental. A Constituição Federal de 1988 condicionou o direito de propriedade ao cumprimento de uma função social, a ser disciplinada pelos planos diretores municipais. O meio ambiente ecologicamente equilibrado foi tido como direito fundamental. A Lei n. 10.257/2001 possibilitou a aplicação prática do princípio. O vigente código civil previu a destinação social da propriedade e a obediência às normas ambientais. Foi concluído ser possível aferir, concretamente, se uma propriedade urbana cumpre sua função social, havendo, inclusive, possibilidade de imposição de penalidades em caso de descumprimento. Entretanto, para essa finalidade, o conteúdo desse conceito não abrange aspectos ambientais, mas apenas parâmetros urbanísticos de aproveitamento do solo.

  10. VizieR Online Data Catalog: NGC 6802 dwarf cluster members and non-members (Tang+, 2017)

    Science.gov (United States)

    Tang, B.; Geisler, D.; Friel, E.; Villanova, S.; Smiljanic, R.; Casey, A. R.; Randich, S.; Magrini, L.; San, Roman I.; Munoz, C.; Cohen, R. E.; Mauro, F.; Bragaglia, A.; Donati, P.; Tautvaisiene, G.; Drazdauskas, A.; Zenoviene, R.; Snaith, O.; Sousa, S.; Adibekyan, V.; Costado, M. T.; Blanco-Cuaresma, S.; Jimenez-Esteban, F.; Carraro, G.; Zwitter, T.; Francois, P.; Jofre, P.; Sordo, R.; Gilmore, G.; Flaccomio, E.; Koposov, S.; Korn, A. J.; Lanzafame, A. C.; Pancino, E.; Bayo, A.; Damiani, F.; Franciosini, E.; Hourihane, A.; Lardo, C.; Lewis, J.; Monaco, L.; Morbidelli, L.; Prisinzano, L.; Sacco, G.; Worley, C. C.; Zaggia, S.

    2016-11-01

    The dwarf stars in NGC 6802 observed by GIRAFFE spectrograph are separated into four tables: 1. cluster members in the lower main sequence; 2. cluster members in the upper main sequence; 3. non-member dwarfs in the lower main sequence; 4. non-member dwarfs in the upper main sequence. The star coordinates, V band magnitude, V-I color, and radial velocity are given. (4 data files).

  11. Renewable energy sources (promotion)

    International Nuclear Information System (INIS)

    Cook, F.

    1986-01-01

    Permission to present a Bill to establish an independent commission directly responsible for the research, development and demonstration of clean, renewable, alternative sources of energy (to nuclear energy) is requested. The paragraphs of the preamble to the Bill are summarized by the Member seeking permission. The main reason for promoting renewable energy sources is opposition to the nuclear industry. One objection was raised. However, permission was granted to present the Bill and it was read for the first time with a second reading ordered for 7 March 1986. The Bill itself is not reprinted but the permission and question are reported verbatim. (U.K.)

  12. ADAM33 gene silencing by promoter hypermethylation as a molecular marker in breast invasive lobular carcinoma

    Directory of Open Access Journals (Sweden)

    de Souza Emanuel M

    2009-03-01

    Full Text Available Abstract Background ADAM33 protein is a member of the family of transmembrane glycoproteins composed of multidomains. ADAM family members have different activities, such as proteolysis and adhesion, making them good candidates to mediate the extracellular matrix remodelling and changes in cellular adhesion that characterise certain pathologies and cancer development. It was reported that one family member, ADAM23, is down-regulated by promoter hypermethylation. This seems to correlate with tumour progression and metastasis in breast cancer. In this study, we explored the involvement of ADAM33, another ADAM family member, in breast cancer. Methods First, we analysed ADAM33 expression in breast tumour cell lines by RT-PCR and western blotting. We also used 5-aza-2'-deoxycytidine (5azadCR treatment and DNA bisulphite sequencing to study the promoter methylation of ADAM33 in breast tumour cell lines. We evaluated ADAM33 methylation in primary tumour samples by methylation specific PCR (MSP. Finally, ADAM33 promoter hypermethylation was correlated with clinicopathological data using the chi-square test and Fisher's exact test. Results The expression analysis of ADAM33 in breast tumour cell lines by RT-PCR revealed gene silencing in 65% of tumour cell lines. The corresponding lack of ADAM33 protein was confirmed by western blotting. We also used 5-aza-2'-deoxycytidine (5-aza-dCR demethylation and bisulphite sequencing methodologies to confirm that gene silencing is due to ADAM33 promoter hypermethylation. Using MSP, we detected ADAM33 promoter hypermethylation in 40% of primary breast tumour samples. The correlation between methylation pattern and patient's clinicopathological data was not significantly associated with histological grade; tumour stage (TNM; tumour size; ER, PR or ERBB2 status; lymph node status; metastasis or recurrence. Methylation frequency in invasive lobular carcinoma (ILC was 76.2% compared with 25.5% in invasive ductal carcinoma

  13. ADAM33 gene silencing by promoter hypermethylation as a molecular marker in breast invasive lobular carcinoma

    International Nuclear Information System (INIS)

    Seniski, Gerusa G; Zanata, Silvio M; Costa, Fabrício F; Klassen, Giseli; Camargo, Anamaria A; Ierardi, Daniela F; Ramos, Edneia AS; Grochoski, Mariana; Ribeiro, Enilze SF; Cavalli, Iglenir J; Pedrosa, Fabio O; Souza, Emanuel M de

    2009-01-01

    ADAM33 protein is a member of the family of transmembrane glycoproteins composed of multidomains. ADAM family members have different activities, such as proteolysis and adhesion, making them good candidates to mediate the extracellular matrix remodelling and changes in cellular adhesion that characterise certain pathologies and cancer development. It was reported that one family member, ADAM23, is down-regulated by promoter hypermethylation. This seems to correlate with tumour progression and metastasis in breast cancer. In this study, we explored the involvement of ADAM33, another ADAM family member, in breast cancer. First, we analysed ADAM33 expression in breast tumour cell lines by RT-PCR and western blotting. We also used 5-aza-2'-deoxycytidine (5azadCR) treatment and DNA bisulphite sequencing to study the promoter methylation of ADAM33 in breast tumour cell lines. We evaluated ADAM33 methylation in primary tumour samples by methylation specific PCR (MSP). Finally, ADAM33 promoter hypermethylation was correlated with clinicopathological data using the chi-square test and Fisher's exact test. The expression analysis of ADAM33 in breast tumour cell lines by RT-PCR revealed gene silencing in 65% of tumour cell lines. The corresponding lack of ADAM33 protein was confirmed by western blotting. We also used 5-aza-2'-deoxycytidine (5-aza-dCR) demethylation and bisulphite sequencing methodologies to confirm that gene silencing is due to ADAM33 promoter hypermethylation. Using MSP, we detected ADAM33 promoter hypermethylation in 40% of primary breast tumour samples. The correlation between methylation pattern and patient's clinicopathological data was not significantly associated with histological grade; tumour stage (TNM); tumour size; ER, PR or ERBB2 status; lymph node status; metastasis or recurrence. Methylation frequency in invasive lobular carcinoma (ILC) was 76.2% compared with 25.5% in invasive ductal carcinoma (IDC), and this difference was

  14. A historical review of promotion strategies for electricity from renewable energy sources in EU countries

    International Nuclear Information System (INIS)

    Haas, Reinhard; Panzer, Christian; Resch, Gustav; Ragwitz, Mario; Held, Anne; Reece, Gemma

    2011-01-01

    The core objective of this paper is to elaborate on historically implemented promotion strategies of renewable energy sources and the associated deployment within the European electricity market. Hence, at a first glance, the historic development of renewable energy sources in the electricity (RES-E) sector is addressed on Member State and on sectoral level as well as consequently discussed according to available RES-E potentials and costs. The specific focus of this paper, are promotion strategies for RES-E options as they are the key driver of an efficient and effective RES-E deployment. Therefore, the paper depicts the main types of different promotion schemes and their properties. Additionally, several cases studies of different European Member States show an in-depth analysis of the different RES-E promotion schemes. In this context, special emphasises are put on the question of effective and efficient promotion scheme designs of different RES-E technologies. Generally, conducted research led to the conclusion, that technology specific financial support measures of RES-E performed much more effective and efficient than others did. Hence, it is not all about the common question of feed-in tariffs vs. quota systems based on tradable green certificates, but more about the design criteria of implemented RES-E support schemes. (author)

  15. Glutamina: Metabolismo, Destinos, Funções E. Relação Com O Exercício Físico

    OpenAIRE

    Francisco, Tatyane Dias; Curi, Tânia Cristina Pithon-; Curi, Rui; Júnior, Jair Rodrigues Garcia

    2008-01-01

    A glutamina é o aminoácido mais abundante no plasma e nos tecidos, especialmente nos músculos. Ela desempenha muitas funções, dentre as quais o transporte de amônia dos tecidos produtores (músculos, por exemplo) para os órgãos que a eliminam (fígado e rins), a doação de esqueletos de carbono para a gliconeogênese, a manutenção do equilíbrio ácido-básico com a libera&cced...

  16. Faculty Agency in Applying for Promotion to Professor

    Directory of Open Access Journals (Sweden)

    Susan K. Gardner

    2017-02-01

    Full Text Available Aim/Purpose: In the United States, faculty who wish to pursue promotion to the rank of professor do so without clear guidance or structure. Even the timing of such a process is nebulous. As such, an individual engages in agentic action to pursue the rank. Background: This study examined the experiences of faculty members who chose to pursue the application process to be promoted to professor but were rejected or dissuaded. Methodology: Utilizing a case study of one institutional setting, we conducted 10 in-depth qualitative interviews. Contribution: Very little is known about the process of promotion to full professor in the U.S. and even less empirical research exists. This study advances knowledge of the process and the experiences of those undertaking it. Findings: We learned that cues from the social context greatly influenced these faculty members’ sense of agency.

  17. The Members of the Agency

    International Nuclear Information System (INIS)

    1999-01-01

    The document lists the 130 Member States of the Agency as of 1 December 1999. The new Member since the last issue of the list (INFCIRC/2/52) is Angola. The dates on which the present 130 Member States became Members, and the state Honduras) whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute are given in an Attachment

  18. Traumatic Brain Injury: A Guide for Caregivers of Service Members and Veterans: Becoming a Family Caregiver for a Service Member/Veteran with TBI. Module 3

    Science.gov (United States)

    2010-04-01

    in fiber from whole grains, fruits, and vegetables, and includes lean cuts of meat , poultry , eggs and other protein sources. A healthy diet also...5 - Helping Your Children Cope with TBI32 “When Tim was starting to read and do word finding, those games were fun activities for the kids to do with...like playing board games , taking a walk or run, or baking cookies. Find activities where everyone in the family can play a role. • In addition to

  19. Attitudes of health sciences faculty members towards interprofessional teamwork and education.

    Science.gov (United States)

    Curran, Vernon R; Sharpe, Dennis; Forristall, Jennifer

    2007-09-01

    Faculty attitudes are believed to be a barrier to successful implementation of interprofessional education (IPE) initiatives within academic health sciences settings. The purpose of this study was to examine specific attributes of faculty members, which might relate to attitudes towards IPE and interprofessional teamwork. A survey was distributed to all faculty members in the medicine, nursing, pharmacy and social work programmes at our institution. Respondents were asked to rate their attitudes towards interprofessional health care teams, IPE and interprofessional learning in an academic setting using scales adopted from the peer-reviewed literature. Information on the characteristics of the respondents was also collected, including data on gender, prior experience with IPE, age and years of practice experience. A total response rate of 63.0% was achieved. Medicine faculty members reported significantly lower mean scores (P nursing faculty on attitudes towards IPE, interprofessional teams and interprofessional learning in the academic setting. Female faculty and faculty who reported prior experience in IPE reported significantly higher mean scores (P teamwork. The findings have implications for both the advancement of IPE within academic institutions and strategies to promote faculty development initiatives. In terms of IPE evaluation, the findings also highlight the importance of measuring baseline attitudinal constructs as part of systematic evaluative activities when introducing new IPE initiatives within academic settings.

  20. Momasi Model in Need Assessment of Faculty Members of Alborz University

    Directory of Open Access Journals (Sweden)

    S. Esmaelzadeh

    2013-02-01

    Full Text Available Background: The first step in developing human resources to improve the performance of universities is to indentify accurate educational needs. Models may draw on a number of theories to help understand a particular problem in a certain setting or context. Momasi model is an integrated of the existing models in educational needs assessment field which has sufficient comprehensiveness of data collection. the aim of this study was application of Momasi model in need assessment of faculty members in seven areas duties. Methods: This study is a cross- sectional study which was formed based on Momasi model between34 faculty members of Alborz university. Results: Different areas of educational needs were respectively prioritized as: personal development, research, administrative and executive activities, education, health services and health promotion, and specialized activities outside the university. The most mean and standard deviation belong to area of research, The first priority in the area of research was the publications in English, in personal development area: familiarity with SPSS software ,and the area of education it was creativity nurture. Conclusion: Based on assessment results, research area in this needs assessment study has the most important priority and frequency. Therefore it is recommended that data gathered in research area section put in first priority for empowering for faculty members Of Alborz University.

  1. Family members' experiences of autopsy

    NARCIS (Netherlands)

    Oppewal, F; Meyboom-de Jong, B

    Background. The experiences of family members will teach us how to handle an autopsy, the ultimate quality assessment tool. Objective. The aim of this study was to determine surviving family members' experience of autopsy. Method. Seven GPs were asked to approach surviving family members of

  2. Median and ulnar neuropathies in U.S. Army Medical Command Band members.

    Science.gov (United States)

    Shaffer, Scott W; Koreerat, Nicholas R; Gordon, Lindsay B; Santillo, Douglas R; Moore, Josef H; Greathouse, David G

    2013-12-01

    Musicians have been reported as having a high prevalence of upper-extremity musculoskeletal disorders, including carpal tunnel syndrome. The purpose of this study was to determine the presence of median and ulnar neuropathies in U.S. Army Medical Command (MEDCOM) Band members at Fort Sam Houston, Texas. Thirty-five MEDCOM Band members (30 males, 5 females) volunteered to participate. There were 33 right-handed musicians, and the mean length of time in the MEDCOM Band was 12.2 yrs (range, 1-30 yrs). Subjects completed a history form, were interviewed, and underwent a physical examination of the cervical spine and bilateral upper extremities. Nerve conduction studies of the bilateral median and ulnar nerves were performed. Electrophysiological variables served as the reference standard for median and ulnar neuropathy and included distal sensory latencies, distal motor latencies, amplitudes, conduction velocities, and comparison study latencies. Ten of the 35 subjects (29%) presented with abnormal electrophysiologic values suggestive of an upper extremity mononeuropathy. Nine of the subjects had abnormal median nerve electrophysiologic values at or distal to the wrist; 2 had bilateral abnormal values. One had an abnormal ulnar nerve electrophysiologic assessment at the elbow. Nine of these 10 subjects had clinical examination findings consistent with the electrophysiological findings. The prevalence of mononeuropathies in this sample of band members is similar to that found in previous research involving civilian musicians (20-36%) and far exceeds that reported in the general population. Prospective research investigating screening, examination items, and injury prevention measures in musicians appears to be warranted.

  3. Microbiologists Just Want to Have Fun

    Directory of Open Access Journals (Sweden)

    Heather M. Seitz

    2012-09-01

    Full Text Available Review of: Non-technical online microbial resources that entertain, engage, and promote microbiology thorugh music, comics, and gaming. Resources include Food Safety Music, Pandemic 2, Microbe Kombat, and The Great Flu.

  4. The Members of the Agency

    International Nuclear Information System (INIS)

    2003-01-01

    The document lists the 135 Member States of the Agency as of 19 March 2003. The new Member since the last issue of the list (INFCIRC/2/56) is the Republic of Honduras. The dates on which the present 135 Member States became Members are given in an Attachment. It also shows the States whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute

  5. The Members of the Agency

    International Nuclear Information System (INIS)

    2002-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.55) is the Republic of Botswana, which deposited the instrument of acceptance of the Statute on 20 March 2002. The Attachment hereto shows the dates on which the present 134 Member States became Members. It also shows the State whose application for membership of the Agency has been approved by the General Conference, but which has not yet deposited an instrument of acceptance of the Statute

  6. The Members of the Agency

    International Nuclear Information System (INIS)

    2001-01-01

    The document lists the 132 Member States of the Agency as of 1 June 2001. The new Members since the last issue of the list (INFCIRC/2/53) are Central African Republic and Azerbaijan. The dates on which the present 132 Member States became Members are given in an Attachment. It also shows the States whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute

  7. Des monastères aux funérailles. La construction d’une relation ethnographique avec des chrétiennes de Damas (Syrie

    Directory of Open Access Journals (Sweden)

    Anna Poujeau

    2009-03-01

    Full Text Available Des monastères aux funérailles. La construction d’une relation ethnographique avec des chrétiennes de Damas (Syrie. En juillet 2004, j’ai assisté aux funérailles d’un jeune homme de la famille au sein de laquelle je vivais à Damas. À l’époque, l’intense émotion suscitée par cet événement empêcha que je m’y intéresse de plus près. Ce n’est que deux ans plus tard, en juillet 2006, que j’ai décidé d’enquêter sur l’un des aspects majeurs de la cérémonie : les lamentations funèbres féminines. Lors de ce dernier terrain, les femmes de la famille que j’interrogeais, que j’accompagnais aux funérailles et dont j’enregistrais les chants m’assignèrent alors une place tout à fait particulière. Puisque, moi aussi, « je m’habillais en noir et je venais aux funérailles », je ne pouvais plus être considérée comme une étrangère. Dès lors, elles firent de moi la fille d’une de leur sœur émigrée à Paris et mariée avec un Français. Ce statut me fut par ailleurs confirmé lorsqu’elles m’attribuèrent une place dans leurs plaisanteries entre sœurs, tantes et neveux matrilatéraux.Dans cet article, je souhaite engager une double réflexion : sur la position et l’implication de l’ethnologue sur un terrain où l’émotion est au premier plan, ainsi que sur la façon dont être assignée à une place dans la parenté de ses informateurs donne enfin toute liberté d’action à l’ethnologue sur son terrain.From monasteries to funerals. The construction of ethnographical relations with the Christians of Damascus (Syria. In July 2004, I attended the funeral of a young man from the family with whom I was staying in Damascus. At the time, the intense emotion provoked by that event prevented me from immediately examining it more closely. It was only two years later, in July 2006, that I decided to study one of the main features of the ceremony: the women’s lamentations. During this

  8. (Dis)função sexual, depressão e ansiedade em pacientes ginecológicas

    OpenAIRE

    Bárbara Braga de Lucena

    2013-01-01

    Os objetivos do presente estudo foram: (1) avaliar a função sexual feminina e a presença de depressão e ansiedade; (2) verificar a associação entre disfunção sexual feminina (DSF), depressão e ansiedade e (3) identificar as variáveis relacionadas com os domínios: desejo, excitação, orgasmo e dor durante a relação sexual Participaram do estudo 110 pacientes saudáveis (idade: 18-61, média:38,5 anos) que aguardavam consulta ambulatorial de prevenção ginecológica no Hospital das Clínicas da Facul...

  9. Payment or Reimbursement for Certain Medical Expenses for Camp Lejeune Family Members. Final rule.

    Science.gov (United States)

    2017-05-05

    The Department of Veterans Affairs (VA) adopts as final an interim final rule addressing payment or reimbursement of certain medical expenses for family members of Camp Lejeune veterans. Under this rule, VA reimburses family members, or pays providers, for medical expenses incurred as a result of certain illnesses and conditions that may be associated with contaminants present in the base water supply at U.S. Marine Corps Base Camp Lejeune (Camp Lejeune), North Carolina, from August 1, 1953, to December 31, 1987. Payment or reimbursement is made within the limitations set forth in statute and Camp Lejeune family members receive hospital care and medical services that are consistent with the manner in which we provide hospital care and medical services to Camp Lejeune veterans. The statutory authority has since been amended to also include certain veterans' family members who resided at Camp Lejeune, North Carolina, for no less than 30 days (consecutive or nonconsecutive) between August 1, 1953, and December 31, 1987. This final rule will reflect that statutory change and will address public comments received in response to the interim final rule.

  10. PROMOTER COMMISSION LEGISLATIVE AND EXTERNAL REPRESENTATIVE OF THE UNION

    Directory of Open Access Journals (Sweden)

    Nely Militaru

    2014-11-01

    Full Text Available Commission was established by the Treaty establishing the Economic Community of Coal and Osel – signed in Paris in 1951, entered into force next year –as the High Authority supranational institution with discretionary decisionmaking powers in optics of this treaty. Also known as “guardian of the treaties” Commission by its member, who exercise their functions in complete independence, is an institution that promotes the general interest of the Union (art. 17 par.TEU. Commission oversees therefore application of Union law. In this capacity, especially in terms of the competence of the legislative proposal, the Commission by calling upon specialists and experts from EU Member States harmonize with the national interest.

  11. Fun cube based brain gym cognitive function assessment system.

    Science.gov (United States)

    Zhang, Tao; Lin, Chung-Chih; Yu, Tsang-Chu; Sun, Jing; Hsu, Wen-Chuin; Wong, Alice May-Kuen

    2017-05-01

    The aim of this study is to design and develop a fun cube (FC) based brain gym (BG) cognitive function assessment system using the wireless sensor network and multimedia technologies. The system comprised (1) interaction devices, FCs and a workstation used as interactive tools for collecting and transferring data to the server, (2) a BG information management system responsible for managing the cognitive games and storing test results, and (3) a feedback system used for conducting the analysis of cognitive functions to assist caregivers in screening high risk groups with mild cognitive impairment. Three kinds of experiments were performed to evaluate the developed FC-based BG cognitive function assessment system. The experimental results showed that the Pearson correlation coefficient between the system's evaluation outcomes and the traditional Montreal Cognitive Assessment scores was 0.83. The average Technology Acceptance Model 2 score was close to six for 31 elderly subjects. Most subjects considered that the brain games are interesting and the FC human-machine interface is easy to learn and operate. The control group and the cognitive impairment group had statistically significant difference with respect to the accuracy of and the time taken for the brain cognitive function assessment games, including Animal Naming, Color Search, Trail Making Test, Change Blindness, and Forward / Backward Digit Span. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Members of young Bosnia between Serbian and Yugoslav identity

    Directory of Open Access Journals (Sweden)

    Mastilović Draga

    2014-01-01

    Full Text Available Although they were considered the ideologists of Yugoslav identity before the First World War, the members of Young Bosnia were not united regarding this issue. This is illustrated by the attitudes of the two main ideologists of the movement Vladimir Gaćinović and Dimitrije Mitrinović. Contrary to Mitrinović, who was one of the most eager promoters of the idea of the unity of the South Slavs, Gaćinović was distrustful of this idea. He understood it as the 'pouring Croatian water in Serbian wine'. Both of them had a big number of followers in students' revolutionary organizations, and these Serb-Croat and Yugoslav organizations were responsible for the Assassination at Sarajevo.

  13. Competitividade empresarial, custos trabalhistas e mercados: possibilidades e limites de reconhecimento da fun??o concorrencial do direito do trabalho

    OpenAIRE

    Lucena Filho, Humberto Lima de

    2016-01-01

    As fun??es cl?ssicas do direito do trabalho arroladas pela doutrina, pela legisla??o e pela jurisprud?ncia especializada n?o contemplam, na esfera nacional, a sonega??o sistem?tica de direitos trabalhistas como conduta suficiente para o enquadramento nas hip?teses de comportamento anticoncorrencial. Ao tempo em que isto se sucede no plano interno, debates e provid?ncias t?m sido tomadas, na seara internacional, no intuito de n?o se permitir que a legisla??o trabalhista seja um instrumento de ...

  14. Uma proposta de utilização de material manipulativo no aprendizado da função exponencial.

    OpenAIRE

    Ricardo Antonio Faustino da Silva Braz

    2006-01-01

    Neste trabalho temos como objetivo geral investigar o uso de material manipulativo no aprendizado da função exponencial, como proposta. Como orientação teórica, temos as pesquisas da professora Josinalva Estacio Menezes, os trabalhos do professor John Andrew Fossa e ainda as contribuições dos trabalhos de Brousseau e Lima, que serviram como apoio ao indicarem suas propostas metodológicas para possíveis superações de uso do referido recurso na sala de aula, como também apontaram literaturas...

  15. Using Cooperative Structures to Promote Deep Learning

    Science.gov (United States)

    Millis, Barbara J.

    2014-01-01

    The author explores concrete ways to help students learn more and have fun doing it while they support each other's learning. The article specifically shows the relationships between cooperative learning and deep learning. Readers will become familiar with the tenets of cooperative learning and its power to enhance learning--even more so when…

  16. Team OSCE: A Teaching Modality for Promotion of Multidisciplinary Work in Mental Health Settings.

    Science.gov (United States)

    Sharma, Manoj Kumar; Chandra, Prabha S; Chaturvedi, Santosh K

    2015-01-01

    The objective structured clinical examination has been in use both as an assessment and a teaching modality within the mental health profession. It focuses on individual skill enhancement, the inter-professional understanding of role obligation is helpful in promoting competence as a team as well as role of other team members. The Team OSCE (TOSCE) is an effective way in promoting inter-professional learning. The present work assesses the trainee experience with TOSCE and its utility in clinical care. Twenty-two mental health trainees (17 male and 5 female from psychiatry, clinical psychology and psychiatric social work) got exposure to weekly OSCAF training as well as 2-3 Team OSCAFS on various aspects of clinical work as a part of their clinical training for 3 months. Rating from the trainees were taken on TOSCE feedback checklist. TOSCE was helpful in promoting the understanding role of other team members; shared decision-making, problem-solving, handling unexpected events, giving feedback and closure. The TOSCE may be introduced as a way to work on clinical performance, shared decision-making and inter-professional understanding.

  17. The members of the Agency

    International Nuclear Information System (INIS)

    1996-01-01

    The new Member since the last list of Member States was issued (INFCIRC/2/Rev.46) is Bosnia and Herzegovina. The Attachment hereto shows the dates on which the present 123 Member States became Members. It also shows the States whose applications for membership of the Agency have been approved by the General Conference but which have not yet deposited an instrument of acceptance of the Statute and the State whose application for membership has been recommended by the Board of Governors for approval by the General Conference

  18. The Members of the Agency

    International Nuclear Information System (INIS)

    1995-01-01

    No new Member has joined the Agency since the last list of Member States was issued (INFCIRC/2/Rev.45). The Attachment hereto shows the dates on which the present 122 Member States became Members. It also shows the State whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute and the States whose applications for membership have been recommended by the Board of Governors for approval by the General Conference

  19. The Members of the Agency

    International Nuclear Information System (INIS)

    2003-01-01

    The document lists the 136 Member States of the Agency as of 6 May 2003. The new Members since the last issue of the list (INFCIRC/2/57) are Eritrea and the Republic of Seychelles. Cambodia withdrew from the Agency with effect from 26 March 2003. The dates on which the present 136 Member States became Members are given in an Attachment. It also shows the States whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute

  20. The Members of the Agency

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-11

    No new Member has joined the Agency since the last list of Member States was issued (INFCIRC/2/Rev.45). The Attachment hereto shows the dates on which the present 122 Member States became Members. It also shows the State whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute and the States whose applications for membership have been recommended by the Board of Governors for approval by the General Conference.