WorldWideScience

Sample records for megaloolithid clutches insights

  1. Unidirectional clutches

    International Nuclear Information System (INIS)

    1981-01-01

    Unidirectional clutches are used in nuclear power plants to protect coolant pumps and associated drive motors against reverse rotation, and as a standby system for coolant pumps. As long life is important the sprag elements should be of a high carbon alloy steel with chromium diffused into the surface for high resistance to corrosion and abrasion. The invention described is of a unidirectional clutch including inner and outer races which can be mechanically coupled together by the action of a plurality of tiltable sprag elements which increases in overall efficiency as they are tilted or rocked in a given direction. To absorb momentary excessive torque the sprag elements have camming surfaces at opposite ends, at least one of which includes an arcuate portion centred on a point lying outside the profile of the sprag element. The extreme limit of the radius of this arcuate portion is the radius of the inner surface of the outer race. The clutch can absorb high torque yet is compact. If an excessive torque is applied it will momentarily release to allow relative movement of the two races so avoiding permanent damage to the clutch. (U.K.)

  2. Electromagnetic clutches and couplings

    CERN Document Server

    Vorob'Yeva, T M; Fry, D W; Higinbotham, W

    2013-01-01

    Electromagnetic Clutches and Couplings contains a detailed description of U.S.S.R. electromagnetic friction clutches, magnetic couplings, and magnetic particle couplings. This book is divided into four chapters. The first chapter discusses the design and construction of magnetic (solenoid-operated) couplings, which are very quick-acting devices and used in low power high-speed servo-systems. Chapter 2 describes the possible fields of application, design, construction, and utilization of magnetic particle couplings. The aspects of construction, design, and utilization of induction clutches (sli

  3. Virtual Clutch Controller for Clutch-to-Clutch Shifts in Planetary-Type Automatic Transmission

    Directory of Open Access Journals (Sweden)

    Yunjiang Cheng

    2015-01-01

    Full Text Available It is known that the shift processes of the four types of clutch-to-clutch shifts can theoretically be divided into two phases which are torque phase and inertia phase, but the execution orders are different. Two virtual clutch controllers are designed with the same eight states which include all control processes for these shifts. An equivalent method is proposed so that AT can be controlled just like DCT by adopting the torque ratios of oncoming clutch and offgoing clutch of each gear. The powertrain system model and the shift controller are established on Matlab/Simulink platform. The clutch-to-clutch shift processes have been studied based on the virtual clutch controller by software-in-the-loop simulations. Some typical problems in the clutch-to-clutch shift control are discussed and several control methods are compared to solve these problems.

  4. Magnetic particle clutch controls servo system

    Science.gov (United States)

    Fow, P. B.

    1973-01-01

    Magnetic clutches provide alternative means of driving low-power rate or positioning servo systems. They may be used over wide variety of input speed ranges and weigh comparatively little. Power drain is good with overall motor/clutch efficiency greater than 50 percent, and gain of clutch is close to linear, following hysteresis curve of core and rotor material.

  5. Clutches and brakes design and selection

    CERN Document Server

    Orthwein, William C

    2004-01-01

    Conveniently gathering formulas, analytical methods, and graphs for the design and selection of a wide variety of brakes and clutches in the automotive, aircraft, farming, and manufacturing industries, Clutches and Brakes: Design and Selection, Second Edition simplifies calculations, acquaints engineers with an expansive range of application, and assists in the selection of parameters for specific design challenges. Contains an abundance of examples, 550 display equations, and more than 200 figures for clear presentation of various design strategies Thoroughly revised throughout, the second edition offers… Additional chapters on friction drives and fluid clutches and retarders An extended discussion on cone brakes and clutches A simpler formulation of the torque from a centrifugal clutch Updated sections on automatic braking systems An analysis of variable-speed friction drives with clutch capability Analytical and computer-assisted design techniques.

  6. Study of a magnetorheological grease clutch

    International Nuclear Information System (INIS)

    Kavlicoglu, Barkan M; Gordaninejad, Faramarz; Wang, Xiaojie

    2013-01-01

    In high-speed viscous clutch applications that require low drag (viscous) torque, magnetorheological (MR) fluids are problematic due to their plastic viscosity. As the clutch speed increases the drag torque might exceed the allowable drag torque limit, because the viscous torque is proportional to the speed. To eliminate this problem, various MR greases are utilized in a clutch and their performance is examined. In the experimental study, the torque transfer capacity of a double-plate clutch for operating speeds up to 1200 rpm is conducted. Six different MR greases with various particle loadings and particle sizes are evaluated in the clutch. The rheological properties of MR grease with 90% particle loading in weight are compared with a commercially available MR fluid. The torque performance of the MR grease clutch is also compared with that of the clutch using MR fluid. It is demonstrated that the off-state (no applied magnetic field) torque output of the MR grease clutch is constant in the tested range of the operating speed. In contrast, the torque capacity of the clutch with MR fluid shows a strong dependence on the operating speed. Moreover, it is shown that the iron particle size of the MR grease does not affect the torque output. The MR greases demonstrated an up to 75% increase in the torque capacity compared to the commercial MR fluid. (paper)

  7. Method and apparatus for executing an asynchronous clutch-to-clutch shift in a hybrid transmission

    Science.gov (United States)

    Demirovic, Besim; Gupta, Pinaki; Kaminsky, Lawrence A.; Naqvi, Ali K.; Heap, Anthony H.; Sah, Jy-Jen F.

    2014-08-12

    A hybrid transmission includes first and second electric machines. A method for operating the hybrid transmission in response to a command to execute a shift from an initial continuously variable mode to a target continuously variable mode includes increasing torque of an oncoming clutch associated with operating in the target continuously variable mode and correspondingly decreasing a torque of an off-going clutch associated with operating in the initial continuously variable mode. Upon deactivation of the off-going clutch, torque outputs of the first and second electric machines and the torque of the oncoming clutch are controlled to synchronize the oncoming clutch. Upon synchronization of the oncoming clutch, the torque for the oncoming clutch is increased and the transmission is operated in the target continuously variable mode.

  8. Performing under pressure: Exploring the psychological state underlying clutch performance in sport.

    Science.gov (United States)

    Swann, Christian; Crust, Lee; Jackman, Patricia; Vella, Stewart A; Allen, Mark S; Keegan, Richard

    2017-12-01

    Clutch performance is improved performance under pressure. However, little research has examined the psychological state experienced by athletes in these situations. Therefore, this study qualitatively examined the subjective experience underlying clutch performance across a range of sports (e.g., team, individual) and standards (Olympic to recreational athletes). Sixteen athletes (M age  = 27.08 years; SD = 6.48) took part in in-depth, semi-structured interviews primarily after an exceptional performance (M = 4.38 days later; SD = 3.14). Data were analysed inductively and thematically. Clutch states involved 12 characteristics, including heightened and deliberate concentration, intense effort, and heightened awareness, which distinguished the experience of clutch from other optimal psychological states such as flow. Other characteristics, such as perceptions of control, were also reported and supported previous experimental research on clutch. These findings present in-depth qualitative insights into the psychological state underlying clutch performance, and are discussed in relation to the existing literature on optimal psychological states in sport.

  9. Electromagnetic brake/clutch device

    Science.gov (United States)

    Vranish, John M. (Inventor)

    1994-01-01

    An electromagnetic brake/clutch device includes a drive shaft supported by at least one bearing for transmitting torque, a housing, affixed to prevent its rotation, surrounding the drive shaft, and an electromagnetically activated device within the housing to selectively prevent and allow rotation of the drive shaft. The electromagnetically activated device includes a plurality of cammed rollers to prevent counter-clockwise rotation of the drive shaft. The drive shaft includes a circumferential disk and the housing includes a reaction ring for engagement with the plurality of cammed rollers. The plurality of cammed rollers are released from engagement with the circumferential disk and the reaction ring by a plurality of tripping mechanisms within the housing. The tripping action uses the locking force to act as a release force merely by changing the boundary conditions of the roller interface angles. The tripping mechanisms include trippers for disengaging the plurality of cammed rollers and an anvil shaped portion for providing lateral movement of the trippers. The plurality of cammed rollers is preloaded to engagement with the circumferential disk and reaction ring by a spring, and is located with respect to an adjacent tripping mechanism with another spring.

  10. Offspring fitness and individual optimization of clutch size

    Science.gov (United States)

    Both, C.; Tinbergen, J. M.; Noordwijk, A. J. van

    1998-01-01

    Within-year variation in clutch size has been claimed to be an adaptation to variation in the individual capacity to raise offspring. We tested this hypothesis by manipulating brood size to one common size, and predicted that if clutch size is individually optimized, then birds with originally large clutches have a higher fitness than birds with originally small clutches. No evidence was found that fitness was related to the original clutch size, and in this population clutch size is thus not related to the parental capacity to raise offspring. However, offspring from larger original clutches recruited better than their nest mates that came from smaller original clutches. This suggests that early maternal or genetic variation in viability is related to clutch size.

  11. A Novel Approach for Enhancement of Automobile Clutch Engagement Quality Using Mechatronics Based Automated Clutch System

    Science.gov (United States)

    Tripathi, K.

    2013-01-01

    In automated manual clutch (AMC) a mechatronic system controls clutch force trajectory through an actuator governed by a control system. The present study identifies relevant characteristics of this trajectory and their effects on driveline dynamics and engagement quality. A new type of force trajectory is identified which gives the good engagement quality. However this trajectory is not achievable through conventional clutch control mechanism. But in AMC a mechatronic system based on electro-hydraulic or electro-mechanical elements can make it feasible. A mechatronic system is presented in which a mechatronic add-on system can be used to implement the novel force trajectory, without the requirement of replacing the traditional diaphragm spring based clutch in a vehicle with manual transmission.

  12. Elevational gradient in clutch size of Red-faced Warblers

    Science.gov (United States)

    Dillon, Kristen G.; Conway, Courtney J.

    2015-01-01

    Our understanding of life history evolution has benefited from debates regarding the underlying causes, and geographic ubiquity, of spatial patterns in avian clutch sizes. Past studies have revealed that birds lay smaller clutch sizes at higher elevation. However, in most previous studies, investigators have failed to adequately control for elevational differences in breeding phenology. To better understand the elevational gradient in avian clutch size, we need to know how clutch size changes across the entire elevational breeding range of a species (i.e., the shape of the relationship between elevation and clutch size), and whether the elevational gradient in clutch size is merely an artifact of elevational gradients in breeding phenology or breeding season length. We examined the relationship between breeding elevation and clutch size of Red-faced Warblers (Cardellina rubrifrons) along a 1000-m elevational gradient in Arizona. Our objectives were to determine how clutch size changed with elevation, and if the relationship between clutch size and elevation merely reflected elevational changes in breeding season length or phenology. The proportion of 5-egg clutches decreased and the proportion of 3- and 4-egg clutches increased non-linearly with increasing elevation, even after controlling for the elevational gradient in nest initiation date. Thus, average clutch size declined across the elevational breeding range of Red-faced Warblers, but this decline was not due to elevational variation in breeding phenology. Timing of breeding changed, but the duration of the breeding season did not change appreciably across the elevational gradient. Hence, elevational differences in breeding season length or breeding phenology cannot explain why Red-faced Warblers (and perhaps other birds) breeding at higher elevations have smaller clutches.

  13. Clutch size declines with elevation in tropical birds

    Science.gov (United States)

    Boyce, A.J.; Freeman, Benjamin G.; Mitchell, Adam E.; Martin, Thomas E.

    2015-01-01

    Clutch size commonly decreases with increasing elevation among temperate-zone and subtropical songbird species. Tropical songbirds typically lay small clutches, thus the ability to evolve even smaller clutch sizes at higher elevations is unclear and untested. We conducted a comparative phylogenetic analysis using data gathered from the literature to test whether clutch size varied with elevation among forest passerines from three tropical biogeographic regions—the Venezuelan Andes and adjacent lowlands, Malaysian Borneo, and New Guinea. We found a significant negative effect of elevation on variation in clutch size among species. We found the same pattern using field data sampled across elevational gradients in Venezuela and Malaysian Borneo. Field data were not available for New Guinea. Both sets of results demonstrate that tropical montane species across disparate biogeographic realms lay smaller clutches than closely related low-elevation species. The environmental sources of selection underlying this pattern remain uncertain and merit further investigation.

  14. Camouflage and Clutch Survival in Plovers and Terns

    Science.gov (United States)

    Stoddard, Mary Caswell; Kupán, Krisztina; Eyster, Harold N.; Rojas-Abreu, Wendoly; Cruz-López, Medardo; Serrano-Meneses, Martín Alejandro; Küpper, Clemens

    2016-09-01

    Animals achieve camouflage through a variety of mechanisms, of which background matching and disruptive coloration are likely the most common. Although many studies have investigated camouflage mechanisms using artificial stimuli and in lab experiments, less work has addressed camouflage in the wild. Here we examine egg camouflage in clutches laid by ground-nesting Snowy Plovers Charadrius nivosus and Least Terns Sternula antillarum breeding in mixed aggregations at Bahía de Ceuta, Sinaloa, Mexico. We obtained digital images of clutches laid by both species. We then calibrated the images and used custom computer software and edge detection algorithms to quantify measures related to three potential camouflage mechanisms: pattern complexity matching, disruptive effects and background color matching. Based on our image analyses, Snowy Plover clutches, in general, appeared to be more camouflaged than Least Tern clutches. Snowy Plover clutches also survived better than Least Tern clutches. Unexpectedly, variation in clutch survival was not explained by any measure of egg camouflage in either species. We conclude that measures of egg camouflage are poor predictors of clutch survival in this population. The behavior of the incubating parents may also affect clutch predation. Determining the significance of egg camouflage requires further testing using visual models and behavioral experiments.

  15. Clutches using engineering ceramics as friction material

    Energy Technology Data Exchange (ETDEWEB)

    Albers, A.; Arslan, A.; Mitariu, M. [Universitaet Karlsruhe (T.H.), IPEK - Institut fuer Produktentwicklung, Kaiserstr. 10, 76131 Karlsruhe (Germany)

    2005-03-01

    The experimental and constructive results illustrate that engineering ceramic materials have a high potential in the field of dry running friction systems. According to first estimations, it is possible to build the vehicle clutch 53 % smaller or to transmit up to 180 % higher torque with the same size by an appropriate selection of the system friction pairing and an adequate ceramic design [1, 2]. The friction coefficient characteristic (decreasing friction coefficient above sliding speed) is unfavourable with regard to comfort (self-induced grab oscillations [3]) of the vehicle clutch. Furthermore, it is important to select the test procedure of the experimental analyses to be as close to the system as possible in order to obtain exact information concerning the target system. (Abstract Copyright [2005], Wiley Periodicals, Inc.) [German] Die experimentellen und konstruktiven Ergebnisse haben gezeigt, dass ingenieurkeramische Werkstoffe ein hohes Potenzial im Bereich der trockenlaufenden Friktionssysteme haben. Durch geeignete Wahl der Systemreibpaarung und eine keramikgerechte Konstruktion ist es nach ersten Abschaetzungen moeglich, die Kfz-Kupplung um 53 % kleiner zu bauen bzw. bei gleicher Groesse bis zu 180 % hoehere Drehmomente zu uebertragen [1, 2]. Die Reibungszahlcharakteristik (fallende Reibungszahl ueber Gleitgeschwindigkeit) ist im Hinblick auf Komfort (selbsterregte Rupfschwingungen [3]) fuer die Kraftfahrzeugkupplung unguenstig. Des Weiteren ist es wichtig, die Versuchsfuehrung der experimentellen Untersuchungen so systemnah wie moeglich zu waehlen, um genauere Aussagen auf das Zielsystem zu erhalten. (Abstract Copyright [2005], Wiley Periodicals, Inc.)

  16. Factors influencing offspring traits in the oviparous multi-clutched ...

    Indian Academy of Sciences (India)

    Unknown

    Calotes versicolor, a multi-clutched oviparous lizard. (Shanbhag and Prasad ... composes correlation between two variables in to: (i) the direct effect of the first ... color breeding time is the prime factor that influences the clutch mass and egg ...

  17. Simulation and control of an automotive dry clutch

    NARCIS (Netherlands)

    Serrarens, A.F.A.; Dassen, M.; Steinbuch, M.

    2004-01-01

    In this paper the dynamic behavior and control of an automotive dry clutch is analyzed. Thereto, a straight-forward model of the clutch is embedded within a dynamic model of an automotive powertrain comprising an internal combustion engine, drivetrain and wheels moving a vehicle through tire-road

  18. A magnetorheological clutch for efficient automotive auxiliary device actuation

    Directory of Open Access Journals (Sweden)

    F. Bucchi

    2013-01-01

    Full Text Available In this paper the results of a project funded by Regione Toscana aimed at reducing the power absorption of auxiliary devices in vehicles are presented. In particular the design, testing and application of a magnetorheological clutch (MR is proposed, aimed at disengaging the vacuum pump, which draws in air from the power-brake booster chamber, in order to reduce the device power absorption. Several clutch preliminary studies done to choose the clutch geometry and the magnetic field supply are illustrated. The final choice consisted in an MR clutch with permanent magnet, which satisfied size, torque and fail-safe specifications. The clutch characteristics, in terms of torque versus slip, were obtained experimentally for three different clutch prototypes on an ad-hoc developed test bench.As result of a preliminary simulation, a comparison between the power absorption of a current production vacuum pump, an innovative vacuum pump and both vacuum pumps coupled with the MR clutch is presented. The New European Driving Cycle is considered for simulating the vacuum pump operation both in urban and highway driving. Results show that the use of the innovative vacuum pump reduces the device consumption of about 35%, whereas the use of MR clutch coupled with the innovative vacuum pump reduces it up to about 44% in urban driving and 50% in highway driving.

  19. Effect of ATF on frictional property of wet-type clutch; Shisshiki crutch (hasshin clutch) no masatsu tokusei ni oyobosu ATF no eikyosei

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, J; Nagashima, T; Yamane, T; Kawauchi, s; Hirao, Y [Honda R and D Co. Ltd., Tokyo (Japan)

    1997-10-01

    As a starting device for continuously variable transmission, wet-type multiple disc clutch installed to the driven side (Starting clutch system) is suitable system. Starting clutch system is feared to occur the judder phenomenon, because it is used at low slipping velocity like a lock up clutch. In this report, we studied to prevent the judder phenomenon about the effect of automatic transmission fluid on frictional property of the wet-type clutch. 6 refs., 7 figs., 2 tabs.

  20. Origin of evolutionary change in avian clutch size.

    Science.gov (United States)

    Haywood, Sacha

    2013-11-01

    Why different bird species lay different numbers of eggs is a question that has long been associated with factors external to the organism, that is, factors which operate on inherited variation in clutch size through the action of natural selection. Yet, while external factors are important, the extent of what is evolutionarily possible rests with the mechanisms developed by birds for clutch-size control. Hitherto neglected, these mechanisms generate factors internal to the organism that are central to the origin of evolutionary change. They are related to the fact that a species-specific range of clutch size arises from the differential survival of pre-ovulatory follicles undergoing growth when the signal causing egg laying to end reaches the ovary. Herein, I examine three internal factors that, together with external factors, could impact the evolution of avian clutch size. Each factor acts by changing either the number of pre-ovulatory follicles present in the ovary at the time of follicular disruption or the timing of this event. These changes to clutch size can be explained by the concept of heterochrony. In light of this, the role of phenotypic plasticity and genes determining clutch size is discussed. Finally, to account for the origin of evolutionary change in clutch size, I detail an hypothesis involving a process similar to Waddington's theory of genetic assimilation. © 2013 The Author. Biological Reviews © 2013 Cambridge Philosophical Society.

  1. Melatonin delays clutch initiation in a wild songbird

    Science.gov (United States)

    Greives, Timothy J.; Kingma, Sjouke A.; Beltrami, Giulia; Hau, Michaela

    2012-01-01

    The hormone melatonin is known to play an important role in regulating many seasonal changes in physiology, morphology and behaviour. In birds, unlike in mammals, melatonin has thus far been thought to play little role in timing seasonal reproductive processes. This view is mainly derived from laboratory experiments on male birds. This study tests whether melatonin is capable of influencing the timing of clutch initiation in wild female songbirds. Free-living female great tits (Parus major) treated with melatonin-filled implants prior to the breeding season initiated their first clutch of the season significantly later than females carrying an empty implant. Melatonin treatment did not affect clutch size. Further, melatonin treatment did not delay the onset of daily activity in the wild nor adversely affect body mass in captivity compared with controls. These data suggest a previously unknown role for this hormone in regulating the timing of clutch initiation in the wild. PMID:22171024

  2. Modeling and Stability Analysis of Wedge Clutch System

    Directory of Open Access Journals (Sweden)

    Jian Yao

    2014-01-01

    Full Text Available A wedge clutch with unique features of self-reinforcement and small actuation force was designed. Its self-reinforcement feature, associated with different factors such as the wedge angle and friction coefficient, brings different dynamics and unstable problem with improper parameters. To analyze this system, a complete mathematical model of the actuation system is built, which includes the DC motor, the wedge mechanism, and the actuated clutch pack. By considering several nonlinear factors, such as the slip-stick friction and the contact or not of the clutch plates, the system is piecewise linear. Through the stability analysis of the linearized system in clutch slipping phase, the stable condition of the designed parameters is obtained as α>arctan⁡(μc. The mathematical model of the actuation system is validated by prototype testing. And with the validated model, the system dynamics in both stable and unstable conditions is investigated and discussed in engineering side.

  3. Peculiar Designing Features of Control Electromagnet Clutch Drives

    Directory of Open Access Journals (Sweden)

    Yu. M. Zakharik

    2005-01-01

    Full Text Available The paper considers fundamentals of control electromagnet clutch drives. Mathematics dependence of electromagnet armature position is proposed and condition of stable drive operation is determined. Recommendations for selection of drive element characteristics are given in the paper.

  4. Advertisement call and tadpole morphology of the clutch-guarding ...

    African Journals Online (AJOL)

    Advertisement call and tadpole morphology of the clutch-guarding frog Mantidactylus argenteus from eastern ... We provide the first descriptions of the tadpole and advertisement call of Mantidactylus argenteus. ... AJOL African Journals Online.

  5. Asbestos exposures of mechanics performing clutch service on motor vehicles.

    Science.gov (United States)

    Cohen, Howard J; Van Orden, Drew R

    2008-03-01

    A study was conducted to assess historical asbestos exposures of mechanics performing clutch service on motor vehicles. For most of the 20th century, friction components used in brakes and manual transmission clutches contained approximately 25-60% chrysotile asbestos. Since the late 1960s, asbestos exposure assessment studies conducted on mechanics performing brake service have frequently reported levels below the current OSHA permissible exposure limit (PEL) of 0.1 fiber/cc (flcc). Although there is a robust asbestos exposure data set for mechanics performing brake service, there are almost no data for mechanics removing and replacing clutches in manual transmission vehicles. Personal and area airborne asbestos samples were collected during the removal of asbestos-containing clutches from 15 manual transmissions obtained from salvage facilities by an experienced mechanic. Clutch plates and debris were analyzed for asbestos using EPA and ISO published analytical methods. More than 100 personal and area air samples were collected and analyzed for asbestos fibers using NIOSH methods 7400 and 7402. A separate study involved a telephone survey of 16 automotive mechanics who began work prior to 1975. The mechanics were asked about the duration, frequency, and methods used to perform clutch service. Wear debris in the bell housing surrounding clutches had an average of 0.1% chrysotile asbestos by weight, a value consistent with similar reports of brake debris. Asbestos air sampling data collected averaged 0.047 flcc. Mechanics participating in the telephone survey indicated that clutch service was performed infrequently, the entire clutch assembly was normally replaced, and there was no need to otherwise handle the asbestos-containing clutch plates. These mechanics also confirmed that wet methods were most frequently used to clean debris from the bell housing. Combining the asbestos exposure that occurred when mechanics performed clutch service, along with the duration

  6. Thermo-mechanical analysis of the pressure plate of clutch

    Directory of Open Access Journals (Sweden)

    P.V.N. Venkata Mallikarjuna

    2017-09-01

    Full Text Available High Temperature appears in the contact surfaces of a clutch system (friction surface and pressure plate due to the relative motion between these parts during the sliding period. These high temperatures are responsible for several failures such as pressure plate crack, pressure plate warpage etc. With the help of Finite element analysis, the sliding friction process of the pressure plate and friction during clutch engagement is simulated to get temperature field characteristics and contact pressure of pressure plate.

  7. Research and Implementation of Tractor Power Shift Clutch Control System

    OpenAIRE

    Li Chengjun; Ke Meicong; Wu Youyu

    2018-01-01

    Applying power shift control technology on tractor can improve the power, economy and driving comfort of tractor. The separation and engagement control of clutch in tractor power shift transmission system is the key factor to optimize the quality of shift. Through many experiments and tests, an electronic control unit based on MC9S12 was developed, and an effective clutch control strategy was put forward, which improved the jerk of power shift and shortened the gear shift time.

  8. Method and apparatus for operating a powertrain system upon detecting a stuck-closed clutch

    Science.gov (United States)

    Hansen, R. Anthony

    2014-02-18

    A powertrain system includes a multi-mode transmission having a plurality of torque machines. A method for controlling the powertrain system includes identifying all presently applied clutches including commanded applied clutches and the stuck-closed clutch upon detecting one of the torque-transfer clutches is in a stuck-closed condition. A closed-loop control system is employed to control operation of the multi-mode transmission accounting for all the presently applied clutches.

  9. Shift concept for starting clutch in powershift transmission; Schaltkonzept fuer Anfahrkupplungen in Lastschaltgetrieben

    Energy Technology Data Exchange (ETDEWEB)

    Grad, Karl; Cappellaro, Thomas [ZF Friedrichshafen AG, Passau (Germany); Oberbuchner, Thomas

    2013-07-15

    In powershift transmissions for tractors the starting clutch represents a core assembly, which is subjected to the highest stresses in use. ZF Friedrichshafen introduces a design in which the thermal stress on the starting clutches can be significantly reduced by changing the clutch actuation. This enables the starting clutches to be dimensioned substantially lighter or to save more space or their function can even be integrated into the powershift clutches.

  10. Road deicing salt irreversibly disrupts osmoregulation of salamander egg clutches

    International Nuclear Information System (INIS)

    Karraker, Nancy E.; Gibbs, James P.

    2011-01-01

    It has been postulated that road deicing salts are sufficiently diluted by spring rains to ameliorate any physiological impacts to amphibians breeding in wetlands near roads. We tested this conjecture by exposing clutches of the spotted salamander (Ambystoma maculatum) to three chloride concentrations (1 mg/L, 145 mg/L, 945 mg/L) for nine days, then transferred clutches to control water for nine days, and measured change in mass at three-day intervals. We measured mass change because water uptake by clutches reduces risks to embryos associated with freezing, predation, and disease. Clutches in controls sequestered water asymptotically. Those in the moderate concentrations lost 18% mass initially and regained 14% after transfer to control water. Clutches in high concentration lost 33% mass and then lost an additional 8% after transfer. Our results suggest that spring rains do not ameliorate the effects of deicing salts in wetlands with extremely high chloride concentrations. - Road deicing salts irreversibly disrupts osmoregulation of salamander egg clutches.

  11. Road deicing salt irreversibly disrupts osmoregulation of salamander egg clutches

    Energy Technology Data Exchange (ETDEWEB)

    Karraker, Nancy E., E-mail: karraker@hku.hk [Department of Environmental and Forest Biology, State University of New York, College of Environmental Science and Forestry, Syracuse, NY 13210 (United States); Gibbs, James P [Department of Environmental and Forest Biology, State University of New York, College of Environmental Science and Forestry, Syracuse, NY 13210 (United States)

    2011-03-15

    It has been postulated that road deicing salts are sufficiently diluted by spring rains to ameliorate any physiological impacts to amphibians breeding in wetlands near roads. We tested this conjecture by exposing clutches of the spotted salamander (Ambystoma maculatum) to three chloride concentrations (1 mg/L, 145 mg/L, 945 mg/L) for nine days, then transferred clutches to control water for nine days, and measured change in mass at three-day intervals. We measured mass change because water uptake by clutches reduces risks to embryos associated with freezing, predation, and disease. Clutches in controls sequestered water asymptotically. Those in the moderate concentrations lost 18% mass initially and regained 14% after transfer to control water. Clutches in high concentration lost 33% mass and then lost an additional 8% after transfer. Our results suggest that spring rains do not ameliorate the effects of deicing salts in wetlands with extremely high chloride concentrations. - Road deicing salts irreversibly disrupts osmoregulation of salamander egg clutches.

  12. Road deicing salt irreversibly disrupts osmoregulation of salamander egg clutches.

    Science.gov (United States)

    Karraker, Nancy E; Gibbs, James P

    2011-03-01

    It has been postulated that road deicing salts are sufficiently diluted by spring rains to ameliorate any physiological impacts to amphibians breeding in wetlands near roads. We tested this conjecture by exposing clutches of the spotted salamander (Ambystoma maculatum) to three chloride concentrations (1 mg/L, 145 mg/L, 945 mg/L) for nine days, then transferred clutches to control water for nine days, and measured change in mass at three-day intervals. We measured mass change because water uptake by clutches reduces risks to embryos associated with freezing, predation, and disease. Clutches in controls sequestered water asymptotically. Those in the moderate concentrations lost 18% mass initially and regained 14% after transfer to control water. Clutches in high concentration lost 33% mass and then lost an additional 8% after transfer. Our results suggest that spring rains do not ameliorate the effects of deicing salts in wetlands with extremely high chloride concentrations. Copyright © 2010 Elsevier Ltd. All rights reserved.

  13. Nest predation risk explains variation in avian clutch size

    Science.gov (United States)

    Dillon, Kristen G.; Conway, Courtney J.

    2018-01-01

    Questions about the ecological drivers of, and mechanistic constraints on, productivity have driven research on life-history evolution for decades. Resource availability and offspring mortality are considered among the 2 most important influences on the number of offspring per reproductive attempt. We used a factorial experimental design to manipulate food abundance and perceived offspring predation risk in a wild avian population (red-faced warblers; Cardellina rubrifrons) to identify the mechanistic cause of variation in avian clutch size. Additionally, we tested whether female quality helped explain the extant variation in clutch size. We found no support for the Food Limitation or Female Quality Hypotheses, but we did find support for both predictions of the Nest Predation Risk Hypothesis. Females that experienced an experimentally heightened perception of offspring predation risk responded by laying a smaller clutch than females in the control group. Additionally, predation rates at artificial nests were highest where red-faced warbler clutch size was smallest (at high elevations). Life-history theory predicts that an individual should invest less in reproduction when high nest predation risk reduces the likely benefit from that nesting attempt and, indeed, we found that birds exhibit phenotypic plasticity in clutch size by laying fewer eggs in response to increasing nest predation risk.

  14. A novel ultrasonic clutch using near-field acoustic levitation.

    Science.gov (United States)

    Chang, Kuo-Tsi

    2004-10-01

    This paper investigates design, fabrication and drive of an ultrasonic clutch with two transducers. For the two transducers, one serving as a driving element of the clutch is connected to a driving shaft via a coupling, and the other serving as a slave element of the clutch is connected to a slave shaft via another coupling. The principle of ultrasonic levitation is first expressed. Then, a series-resonant inverter is used to generate AC voltages at input terminals of each transducer, and a speed measuring system with optic sensors is used to find the relationship between rotational speed of the slave shaft and applied voltage of each transducer. Moreover, contact surfaces of the two transducers are coupled by the frictional force when both the two transducers are not energized, and separated using the ultrasonic levitation when at least one of the two transducers is energized at high voltages at resonance.

  15. Ergonomic assessment of drivers in MF285 and MF399 tractors during clutching using algometer

    Directory of Open Access Journals (Sweden)

    Hossein Fallahi

    2016-03-01

    The results showed that the clutching forces for MF285 and MF399 tractors were 340 N and 290 N, respectively. The knee angle of the drivers of the two tractors was statistically different at the one percent level of significance. The reduction of pain threshold after 30 and 60 s clutching and also 60 s rest after clutching in MF285 tractor, for all three muscles, were more than those of MF399 tractor. The impact of clutching on the average decreases of pain threshold, for all drivers and all clutching periods, during and after clutching, in the Quadratus lumborum muscle was more than the other two muscles, in both tractors. In order to reduce the clutching force for MF285 tractor some modifications is suggested. In this regard the force transfer joint between the pedal and the clutch release linkage may be replaced with one made of cast iron.

  16. Switched causual modeling of transmission with clutch in hybrid electric vehicles

    OpenAIRE

    LHOMME, W; TRIGUI, R; DELARU, P; JEANNERET, B; BOUSCAUROL, A; BADIN, F

    2008-01-01

    Certain difficulties arise when attempting to model a clutch in a power train transmission due to its nonlinear behavior. Two different states have to be taken into account-the first being when the clutch is locked and the second being when the clutch is slipping. In this paper, a clutch model is developed using the Energetic Macroscopic Representation, which is, in turn, used in the modeling of complete hybrid electric vehicles (HEVs). Two different models are used, and a specific condition ...

  17. Strong but variable associations between social dominance and clutch sex ratio in a colonial corvid

    NARCIS (Netherlands)

    Salomons, H. M.; Dijkstra, C.; Verhulst, S.

    2008-01-01

    We studied primary sex ratio of clutches in relation to social dominance for 6 years in a colony of free-living jackdaws, a small corvid. Social dominance was strongly associated with clutch sex ratio, with the difference in clutch sex ratio between the most and least dominant pairs being 30-40%. To

  18. Fitness cost of incubation in great tits (Parus major) is related to clutch size

    Science.gov (United States)

    de Heij, Maaike E; van den Hout, Piet J; Tinbergen, Joost M

    2006-01-01

    Life-history theory predicts that parents produce the number of offspring that maximizes their fitness. In birds, natural selection on parental decisions regarding clutch size may act during egg laying, incubation or nestling phase. To study the fitness consequences of clutch size during the incubation phase, we manipulated the clutch sizes during this phase only in three breeding seasons and measured the fitness consequences on the short and the long term. Clutch enlargement did not affect the offspring fitness of the manipulated first clutches, but fledging probability of the subsequent clutch in the same season was reduced. Parents incubating enlarged first clutches provided adequate care for the offspring of their first clutches during the nestling phase, but paid the price when caring for the offspring of their second clutch. Parents that incubated enlarged first clutches had lower local survival in the 2 years when the population had a relatively high production of second clutches, but not in the third year when there was a very low production of second clutches. During these 2 years, the costs of incubation were strong enough to change positive selection, as established by brood size manipulations in this study population, into stabilizing selection through the negative effect of incubation on parental fitness. PMID:16928638

  19. note on variable incubation period within a clutch of eggs

    African Journals Online (AJOL)

    Compo Biochem. Physiol. 53A: 1-6. MENDELSOHN, 1. M., BIGOS, H. C. & LEDGER, 1. A. In press. The biology of the black-shouldered. NOTE ON VARIABLE. INCUBATION PERIOD WITHIN A. CLUTCH OF EGGS OF THE. LEOPARD TORTOISE. (GEOCHELONE P ARDALIS). (CHELONIA: CRYPTODIRA: TESTUDINIDAE).

  20. A conceptual framework for clutch size evolution in songbirds

    Science.gov (United States)

    Martin, Thomas E.

    2014-01-01

    Causes of evolved differences in clutch size among songbird species remain debated. I propose a new conceptual framework that integrates aspects of traditional life history theory, while including novel elements, to explain evolution of clutch size among songbirds. I review evidence that selection by nest predation on length of time that offspring develop in the nest creates a gradient in offspring characteristics at nest-leaving (fledging), including flight mobility, spatial dispersion, and self-feeding rate. I postulate that this gradient has consequences for offspring mortality rates and parental energy expenditure per offspring. These consequences then determine how reproductive effort is partitioned among offspring, while reproductive effort evolves from age-specific mortality effects. Using data from a long-term site in Arizona, as well as from the literature, I provide support for hypothesized relationships. Nestling development period consistently explains fledgling mortality, energy expenditure per offspring, and clutch size while accounting for reproductive effort (i.e., total energy expenditure) to thereby support the framework. Tests in this paper are not definitive, but they document previously unrecognized relationships and address diverse traits (developmental strategies, parental care strategies, energy requirements per offspring, evolution of reproductive effort, clutch size) that justify further investigations of hypotheses proposed here.

  1. Diapause in Calanoid Copepods: within-clutch hatching patterns

    Directory of Open Access Journals (Sweden)

    Bart T. DE STASIO

    2004-09-01

    Full Text Available Diapause is a major life history feature of many invertebrate organisms. Determining the phenology of diapause is critical for understanding survival and reproductive success of individuals as well as the long-term viability of many populations. The time spent in dormancy by individuals and variability among offspring in the duration of dormancy are two important aspects of invertebrate life histories. Some data are available, especially on duration of diapause, for plants and insects, but little information is available concerning variability among offspring in diapause traits. This is especially true for crustacean zooplankton, where essentially no information has been published on duration of diapause or variability among offspring in diapause timing or dynamics. Here I present data on the duration of diapause, and variability among offspring for diapause characteristics. The freshwater calanoid copepod Onychodiaptomus sanguineus, an obligately sexual species, was collected from Bullhead Pond, Rhode Island, U.S.A., and raised under conditions in the laboratory to induce production of diapausing eggs. One hundred clutches of these diapausing eggs (920 total eggs were incubated for over two years in a full-factorial experiment testing the effects of temperature and photoperiod cycles on the hatching dynamics and duration of diapause. Overall hatching success was highest (approximately 86% for eggs exposed to simultaneous temperature and photoperiod cycles mimicking natural changes, and was lowest (approximately 20% when eggs were incubated at constant temperature (4 °C and in constant dark conditions. The highest fraction of eggs hatched at approximately 550 days of age, but the age of eggs at hatching was highly variable among clutches. There was also large variability within clutches for hatching patterns, with some clutches containing eggs that all hatched synchronously and others in which eggs hatched more continuously throughout the

  2. Differences in size between first and replacement clutches match the seasonal decline in single clutches in Tree Swallows

    NARCIS (Netherlands)

    Karagicheva, J.; Liebers, M.; Rakhimberdiev, E.; Hallinger, K.; Saveliev, A.; Winkler, D.W.

    2016-01-01

    The seasonal decline in clutch size in birds can be a response to the environmentallyconditioned decrease in prospects for offspring or a consequence of a lower physical abilityof late-breeding females. To find out which of the explanations apply in Tree SwallowsTachycineta bicolor, we assessed

  3. The Evolution of Clutch Size in Hosts of Avian Brood Parasites.

    Science.gov (United States)

    Medina, Iliana; Langmore, Naomi E; Lanfear, Robert; Kokko, Hanna

    2017-11-01

    Coevolution with avian brood parasites shapes a range of traits in their hosts, including morphology, behavior, and breeding systems. Here we explore whether brood parasitism is also associated with the evolution of host clutch size. Several studies have proposed that hosts of highly virulent parasites could decrease the costs of parasitism by evolving a smaller clutch size, because hosts with smaller clutches will lose fewer progeny when their clutch is parasitized. We describe a model of the evolution of clutch size, which challenges this logic and shows instead that an increase in clutch size (or no change) should evolve in hosts. We test this prediction using a broad-scale comparative analysis to ask whether there are differences in clutch size within hosts and between hosts and nonhosts. Consistent with our model, this analysis revealed that host species do not have smaller clutches and that hosts that incur larger costs from raising a parasite lay larger clutches. We suggest that brood parasitism might be an influential factor in clutch-size evolution and could potentially select for the evolution of larger clutches in host species.

  4. A new method for speed control of a DC motor using magnetorheological clutch

    Science.gov (United States)

    Nguyen, Quoc Hung; Choi, Seung-Bok

    2014-03-01

    In this research, a new method to control speed of DC motor using magnetorheological (MR) clutch is proposed and realized. Firstly, the strategy of a DC motor speed control using MR clutch is proposed. The MR clutch configuration is then proposed and analyzed based on Bingham-plastic rheological model of MR fluid. An optimal designed of the MR clutch is then studied to find out the optimal geometric dimensions of the clutch that can transform a required torque with minimum mass. A prototype of the optimized MR clutch is then manufactured and its performance characteristics are experimentally investigated. A DC motor speed control system featuring the optimized MR clutch is designed and manufactured. A PID controller is then designed to control the output speed of the system. In order to evaluate the effectiveness of the proposed DC motor speed control system, experimental results of the system such as speed tracking performance are obtained and presented with discussions.

  5. Extending the molecular clutch beyond actin-based cell motility

    International Nuclear Information System (INIS)

    Havrylenko, Svitlana; Mezanges, Xavier; Batchelder, Ellen; Plastino, Julie

    2014-01-01

    Many cell movements occur via polymerization of the actin cytoskeleton beneath the plasma membrane at the front of the cell, forming a protrusion called a lamellipodium, while myosin contraction squeezes forward the back of the cell. In what is known as the ‘molecular clutch’ description of cell motility, forward movement results from the engagement of the acto-myosin motor with cell-matrix adhesions, thus transmitting force to the substrate and producing movement. However during cell translocation, clutch engagement is not perfect, and as a result, the cytoskeleton slips with respect to the substrate, undergoing backward (retrograde) flow in the direction of the cell body. Retrograde flow is therefore inversely proportional to cell speed and depends on adhesion and acto-myosin dynamics. Here we asked whether the molecular clutch was a general mechanism by measuring motility and retrograde flow for the Caenorhabditis elegans sperm cell in different adhesive conditions. These cells move by adhering to the substrate and emitting a dynamic lamellipodium, but the sperm cell does not contain an acto-myosin cytoskeleton. Instead the lamellipodium is formed by the assembly of major sperm protein, which has no biochemical or structural similarity to actin. We find that these cells display the same molecular clutch characteristics as acto-myosin containing cells. We further show that retrograde flow is produced both by cytoskeletal assembly and contractility in these cells. Overall this study shows that the molecular clutch hypothesis of how polymerization is transduced into motility via adhesions is a general description of cell movement regardless of the composition of the cytoskeleton. (paper)

  6. Clutch frequency affects the offspring size-number trade-off in lizards.

    Directory of Open Access Journals (Sweden)

    Zheng Wang

    2011-01-01

    Full Text Available Studies of lizards have shown that offspring size cannot be altered by manipulating clutch size in species with a high clutch frequency. This raises a question of whether clutch frequency has a key role in influencing the offspring size-number trade-off in lizards.To test the hypothesis that females reproducing more frequently are less likely to tradeoff offspring size against offspring number, we applied the follicle ablation technique to female Eremias argus (Lacertidae from Handan (HD and Gonghe (GH, the two populations that differ in clutch frequency. Follicle ablation resulted in enlargement of egg size in GH females, but not in HD females. GH females switched from producing a larger number of smaller eggs in the first clutch to a smaller number of larger eggs in the second clutch; HD females showed a similar pattern of seasonal shifts in egg size, but kept clutch size constant between the first two clutches. Thus, the egg size-number trade-off was evident in GH females, but not in HD females.As HD females (mean  = 3.1 clutches per year reproduce more frequently than do GH females (mean  = 1.6 clutches per year, our data therefore validate the hypothesis tested. Our data also provide an inference that maximization of maternal fitness could be achieved in females by diverting a large enough, rather than a higher-than-usual, fraction of the available energy to individual offspring in a given reproductive episode.

  7. Is the evolution of clutch size limited by incubation ability in shorebirds?

    OpenAIRE

    Beatty, Jessica Lynne

    2015-01-01

    Incubation is a crucial aspect of avian life history where differences in incubation techniques and investments can have long lasting effects on offspring and parental well- being and reproductive success. The factors limiting why some birds, such as shorebirds, have fixed clutch sizes has intrigued life history theorist to propose different hypotheses about the evolution of clutch size. Lack's "incubation limitation hypothesis," suggesting that clutch size is limited by the amount of eggs a ...

  8. Evolution of parental incubation behaviour in dinosaurs cannot be inferred from clutch mass in birds

    OpenAIRE

    Birchard, Geoffrey F.; Ruta, Marcello; Deeming, D. Charles

    2013-01-01

    A recent study proposed that incubation behaviour (i.e. type of parental care) in theropod dinosaurs can be inferred from an allometric analysis of clutch volume in extant birds. However, the study in question failed to account for factors known to affect egg and clutch size in living bird species. A new scaling analysis of avian clutch mass demonstrates that type of parental care cannot be distinguished by conventional allometry because of the confounding effects of phylogeny and hatchling m...

  9. Nest predation, clutch size, and physiological costs of egg production in the song sparrow (Melospiza melodia)

    OpenAIRE

    Travers, Marc Simon

    2009-01-01

    We examined the effects of nest predation on both clutch size and the physiological cost of egg production using a clutch removal experiment in free-living song sparrows (Melospiza melodia), inducing “high nest predation” (HNP) females to produce many replacement clutches compared to “low nest predation” (LNP) females. In a preliminary analysis we investigated the utility of multiple measures to assess “physiological condition”, including inter-correlations between physiological traits, sex d...

  10. Temperature control of an automotive engine cooling system utilizing a magneto-rheological fan clutch

    International Nuclear Information System (INIS)

    Kim, Eun-Seok; Choi, Seung-Bok; Park, Young-Gee; Lee, Soojin

    2010-01-01

    In this note, the temperature control of an automotive engine cooling system is undertaken using a magneto-rheological (MR) fluid-based fan clutch (MR fan clutch in short). In order to achieve this goal, an appropriate size of controllable fan clutch using an MR fluid is firstly devised by considering the design parameters of a conventional fan clutch to reflect the practical application. Then, the principal design parameters of the MR fan clutch such as the length of the disc are optimally determined through finite element analysis. The drum-type MR fan clutch is manufactured and its time response to input current is experimentally evaluated. A robust sliding mode controller is then formulated by treating the time constant of the fan clutch system as an uncertain parameter. After identifying the relationship between angular velocity of the MR fan clutch and the temperature of the cooling system, the sliding mode controller is experimentally realized for the cooling system. It has been clearly demonstrated that the proposed sliding mode controller follows well the desired temperature with a small regulating error. It is expected from this feasibility work that the proposed control system associated with an MR fan clutch can be effectively utilized for the automotive cooling system to improve the fuel efficiency. (technical note)

  11. Adaptive Tracking Control of an Electro-Pneumatic Clutch Actuator

    Directory of Open Access Journals (Sweden)

    Glenn-Ole Kaasa

    2003-10-01

    Full Text Available This paper deals with the application of a simple adaptive algorithm for robust tracking control of an electro-pneumatic clutch actuator with output feedback. We present a mathematical model of the strongly nonlinear system, and implement an adaptive algorithm, based on a parallel feedforward compensator (PFC to remove the relative-degree-1 restriction. We propose a practical method of constructing the PFC, and introduce a simple modification that removes an inherent restriction on bandwidth of the nonlinear system. We show that the adaptive algorithm deals well with nonlinearities, and we achieve tracking corresponding to a settling-time of 150 ms.

  12. High renesting rates in arctic-breeding Dunlin (Calidris alpina): A clutch-removal experiment

    Science.gov (United States)

    Gates, H. River; Lanctot, Richard B.; Powell, Abby N.

    2013-01-01

    The propensity to replace a clutch is a complex component of avian reproduction and poorly understood. We experimentally removed clutches from an Arctic-breeding shorebird, the Dunlin (Calidris alpina arcticola), during early and late stages of incubation to investigate replacement clutch rates, renesting interval, and mate and site fidelity between nesting attempts. In contrast to other Arctic studies, we documented renesting by radiotracking individuals to find replacement clutches. We also examined clutch size and mean egg volume to document changes in individual females’ investment in initial and replacement clutches. Finally, we examined the influence of adult body mass, clutch volume, dates of clutch initiation and nest loss, and year on the propensity to renest. We found high (82–95%) and moderate (35–50%) rates of renesting for early and late incubation treatments. Renesting intervals averaged 4.7–6.8 days and were not different for clutches removed early or late in incubation. Most pairs remained together for renesting attempts. Larger females were more likely to replace a clutch; female body mass was the most important parameter predicting propensity to renest. Clutches lost later in the season were less likely to be replaced. We present evidence that renesting is more common in Arctic-breeding shorebirds than was previously thought, and suggest that renesting is constrained by energetic and temporal factors as well as mate availability. Obtaining rates of renesting in species breeding at different latitudes will help determine when this behavior is likely to occur; such information is necessary for demographic models that include individual and population-level fecundity estimates.

  13. FEATURES OF CONTROLLING ELECTROPNEUMATIC VALVES OF ACTUATOR TO CONTROL ITS CLUTCH WITH ACCELERATION VALVE

    Directory of Open Access Journals (Sweden)

    O. A. Yaryta

    2018-01-01

    Full Text Available The article deals with one of the ways to control an actuator of the automated clutch control system. The aim is to design control of the electropneumatic actuator, to control its coupling with the acceleration valve on the basis of experimental research as well as to provide rational parameters of the automated clutch control system for the robotic transmission. The feature of the system is an acceleration valve in the design of the electropneumatic actuator to control the clutch. New links demand to adjust the way to control the actuator. The connection of Pulse-Width Modulation (PWM with single power supply pulses to control electropneumatic valves is substantiated. The quantitative characteristics of single control pulses and PWM ones are determined. The error of operation accuracy for various ways of the control of the electropneumatic actuator to control the clutch of the robotic transmission is determined. Obtained separate PWM area is designed to suppress the initial hysteresis when the rod of the clutch actuator is moved. An algorithm for the operation of a clutch control system is proposed, taking into account the use of two modes of operation of solenoid valves. A graphical interpretation of the clutch control algorithm is presented, which gives an idea of the location of the constant signal feeding zones to the solenoid valve, as well as the operation areas of the solenoid valve in PWM mode. The control algorithm of the clutch booster provides a mode of guaranteed absence of excess pressure in the pneumatic cylinder after releasing the clutch pedal, provided that two normally closed solenoid valves are used. This configuration of the electro-pneumatic clutch control system allows the use of an emergency clutch release system in case of voltage absence. The reference algorithm for filtering the array of data coming from the feedback sensor, as well as the numerical values of the delay caused by the presence of a filter, are given.

  14. The geometric clutch at 20: stripping gears or gaining traction?

    Science.gov (United States)

    Lindemann, Charles B; Lesich, Kathleen A

    2015-08-01

    It has been 20 years since the geometric clutch (GC) hypothesis was first proposed. The core principle of the GC mechanism is fairly simple. When the axoneme of a eukaryotic flagellum is bent, mechanical stress generates forces transverse to the outer doublets (t-forces). These t-forces can push doublets closer together or pry them apart. The GC hypothesis asserts that changes in the inter-doublet spacing caused by t-forces are responsible for the activation and deactivation of the dynein motors, that creates the beat cycle. A series of computer models utilizing the clutch mechanism has shown that it can simulate ciliary and flagellar beating. The objective of the present review is to assess where things stand with the GC hypothesis in the clarifying light of new information. There is considerable new evidence to support the hypothesis. However, it is also clear that it is necessary to modify some of the original conceptions of the hypothesis so that it can be consistent with the results of recent experimental and ultrastructural studies. In particular, dynein deactivation by t-forces must be able to occur with dyneins that remain attached to the B-subtubule of the adjacent doublet. © 2015 Society for Reproduction and Fertility.

  15. Fitness cost of incubation in great tits (Parus major) is related to clutch size

    NARCIS (Netherlands)

    de Heij, Maaike E.; van den Hout, Piet J.; Tinbergen, Joost M.

    2006-01-01

    Life-history theory predicts that parents produce the number of offspring that maximizes their fitness. In birds, natural selection on parental decisions regarding clutch size may act during egg laying, incubation or nestling phase. To study the fitness consequences of clutch size during the

  16. Females paired with new and heavy mates reduce intra-clutch differences in resource allocation.

    Directory of Open Access Journals (Sweden)

    Maud Poisbleau

    Full Text Available Reproductive investment affects both offspring and parental fitness and influences the evolution of life histories. Females may vary their overall primary reproductive effort in relation to the phenotypic characteristics of their mate. However, the effects of male quality on differential resource allocation within clutches have been largely neglected despite the potential implications for mate choice and population dynamics, especially in species exhibiting biparental care and brood reduction. Female southern rockhopper penguins Eudyptes chrysocome paired with heavy mates reduced intra-clutch variation in egg and albumen masses. Females paired with new mates also reduced intra-clutch variation in yolk androgen levels. Since both an increased mass and increased androgen concentrations positively influence chick survival under sibling competition, the chances of fledging the whole clutch are likely to be higher for newly formed pairs with heavy males than for previously formed pairs with light males. Interestingly, total clutch provisioning did not vary with male quality. We show for the first time that females vary intra-clutch variation in resource allocation according to male quality. In species with brood reduction, it may be more adaptive for females to modulate the distribution of resources within the clutch according to breeding conditions, than to change their total clutch provisioning.

  17. Development of magneto-rheologial fluid (MRF) based clutch for output torque control of AC motors

    Science.gov (United States)

    Nguyen, Q. Hung; Do, H. M. Hieu; Nguyen, V. Quoc; Nguyen, N. Diep; Le, D. Thang

    2018-03-01

    In industry, the AC motor is widely used because of low price, power availability, low cost maintenance. The main disadvantages of AC motors compared to DC motors are difficulty in speed and torque control, requiring expensive controllers with complex control algorithms. This is the basic limitations in the widespread adoption of AC motor systems for industrial automation. One feasible solution for AC motor control is using MRF (magneto-rheological fluid) based clutches (shortly called MR clutches) Although there have been many studies on MR clutches, most of these clutches used traditional configuration with coils wound on the middle cylindrical part and a compotator is used to supply power to the coils. Therefore, this type of MR clutches possesses many disadvantages such as high friction and unstable applied current due to commutator, complex structure which causes difficulty in manufacture, assembly, and maintenance. In addition, the bottleneck problem of magnetic field is also a challenging issue. In this research, we will develop a new type of MR clutches that overcomes the abovementioned disadvantages of traditional MR clutches and more suitable for application in controlling of AC motor. Besides, in this study, speed and torque control system for AC motors using developed MR clutches is designed and experimental validated.

  18. Organochlorine contaminants in complete clutches of Morelet's crocodile (Crocodylus moreletii) eggs from Belize

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Ted H. [Department of Chemistry and Biochemistry, University of Alaska Fairbanks, Fairbanks, AK 99775-6160 (United States); Canas, Jaclyn E. [Institute of Environmental and Human Health, Texas Tech University, Box 41163, Lubbock, TX 79409 (United States); Rainwater, Thomas R. [Institute of Environmental and Human Health, PO Box 764, Jefferson, TX 75657 (United States); Platt, Steven G. [Department of Math and Science, Oglala Lakota College, 490 Piya Wiconi Road, Kyle, SD, 57752 (United States); McMurry, Scott T. [Institute of Environmental and Human Health, Texas Tech University, Box 41163, Lubbock, TX 79409 (United States); Anderson, Todd A. [Institute of Environmental and Human Health, Texas Tech University, Box 41163, Lubbock, TX 79409 (United States)]. E-mail: todd.anderson@ttu.edu

    2006-11-15

    Seven complete clutches of Morelet's crocodile (Crocodylus moreletii) eggs were collected in northern Belize and examined for organochlorine (OC) pesticide residues. The primary OC detected, p,p-DDE, was found in every egg analyzed (n = 175). Other OCs detected included p,p-DDT, p,p-DDD, methoxychlor, aldrin, and endosulfan I. Concentrations of individual OCs ranged from 4 ppb (ng chemical/g egg wet weight) to greater than 500 ppb. A statistical evaluation of p,p-DDE levels in three complete clutches was used to derive the minimum number of eggs needed from a clutch to precisely determine the mean p,p-DDE concentration representative of that clutch. Sample sizes of 8 (80% confidence level) and 11 (90% confidence level) were determined to yield an accurate estimate of contaminant levels in a full clutch of eggs. The statistically recommended sample size of 11 eggs (at 90% confidence level) was successfully tested on the four additional clutches. -- Sampling the non-viable eggs of a clutch can provide a statistically reasonable estimation of both the organochlorine contaminant distribution and concentrations in that clutch.

  19. Modeling and analysis of friction clutch at a driveline for suppressing car starting judder

    Science.gov (United States)

    Li, Liping; Lu, Zhaijun; Liu, Xue-Lai; Sun, Tao; Jing, Xingjian; Shangguan, Wen-Bin

    2018-06-01

    Car judder is a kind of back-forth vibration during vehicle starting which caused by the torsional oscillation of the driveline. This paper presents a systematic study on the dynamic response characteristics of the clutch driven disc for suppression of the judder during vehicle starting. Self-excited vibration behavior of the clutch driven disc is analyzed based on the developed 4DOF non-linear multi-body dynamic model of the clutch driving process considering stick-slip characteristics and using Karnopp friction models. Physical parameters of a clutch determining the generations of the judder behaviors are discussed and the revised designs of the driven disc of a clutch for suppression of the judder are consequently investigated and validated with experiments for two real cars.

  20. Finite element fatigue analysis of rectangular clutch spring of automatic slack adjuster

    Science.gov (United States)

    Xu, Chen-jie; Luo, Zai; Hu, Xiao-feng; Jiang, Wen-song

    2015-02-01

    The failure of rectangular clutch spring of automatic slack adjuster directly affects the work of automatic slack adjuster. We establish the structural mechanics model of automatic slack adjuster rectangular clutch spring based on its working principle and mechanical structure. In addition, we upload such structural mechanics model to ANSYS Workbench FEA system to predict the fatigue life of rectangular clutch spring. FEA results show that the fatigue life of rectangular clutch spring is 2.0403×105 cycle under the effect of braking loads. In the meantime, fatigue tests of 20 automatic slack adjusters are carried out on the fatigue test bench to verify the conclusion of the structural mechanics model. The experimental results show that the mean fatigue life of rectangular clutch spring is 1.9101×105, which meets the results based on the finite element analysis using ANSYS Workbench FEA system.

  1. Study on the Control Strategy of Shifting Time Involving Multigroup Clutches

    Directory of Open Access Journals (Sweden)

    Zhen Zhu

    2016-01-01

    Full Text Available This paper focuses on the control strategy of shifting time involving multigroup clutches for a hydromechanical continuously variable transmission (HMCVT. The dynamic analyses of mathematical models are presented in this paper, and the simulation models are used to study the control strategy of HMCVT. Simulations are performed in Simulation X platform to investigate the shifting time of clutches under different operating conditions. On this basis, simulation analysis and test verification of two typical conditions, which play the decisive roles for the shifting quality, are carried out. The results show that there are differences in the shifting time of the two typical conditions. In the shifting process from the negative transmission of hydromechanical ranges to the positive transmission of hydromechanical ranges, the control strategy based on the shifting time is switching the clutches of shifting mechanism firstly and then disengaging a group of clutches of planetary gear mechanism and engaging another group of the clutches of planetary gear mechanism lastly. In the shifting process from the hydraulic range to the hydromechanical range, the control strategy based on the shifting time is switching the clutches of hydraulic shifting mechanism and planetary gear mechanism at first and then engaging the clutch of shifting mechanism.

  2. Clutch size in populations and species of cnemidophorines (Squamata: Teiidae on the eastern coast of Brazil

    Directory of Open Access Journals (Sweden)

    VANDERLAINE A. MENEZES

    2014-06-01

    Full Text Available We analyzed some reproductive aspects of 16 coastal populations, belonging to five lizard species (A. ocellifera, A. abaetensis, A. nativo, A. littoralis and C. lacertoides from different restinga habitats along the eastern coast of Brazil. This study aimed to evaluate to what extent the reproductive aspects vary geographically and among species. For each female, we recorded the number of vitellogenic follicles, size and color of the largest follicle, presence and size of corpora lutea, and number and size of oviductal eggs. Clutch size of almost all coastal populations/species of Ameivula had little variation and most clutches were composed of two eggs. There was a significant relationship between female size and the mean clutch size when females from different species were pooled. Mean egg volume, among species, varied from 420 to 655 mm3. Relative clutch mass varied from 0.129 to 0.159 and did not differ significantly among species. We concluded that the five coastal species studied (four bisexuals and one parthenogenetic had similar reproductive characteristics. Most of them presented multiple clutches, low clutch size and low relative clutch mass, similar to other species in the genus and to unisexual and bisexual species of the Teiidae family.

  3. On the Energy Efficiency of Dual Clutch Transmissions and Automated Manual Transmissions

    Directory of Open Access Journals (Sweden)

    Fabio Vacca

    2017-10-01

    Full Text Available The main benefits of dual clutch transmissions (DCTs are: (i a higher energy efficiency than automatic transmission systems with torque converters; and (ii the capability to fill the torque gap during gear shifts to allow seamless longitudinal acceleration profiles. Therefore, DCTs are viable alternatives to automated manual transmissions (AMTs. For vehicles equipped with engines that can generate considerable torque, large clutch-slip energy losses occur during power-on gear shifts and, as a result, DCTs need wet clutches for effective heat dissipation. This requirement substantially reduces DCT efficiency because of the churning and ancillary power dissipations associated with the wet clutch pack. To the knowledge of the authors, this study is the first to analyse the detailed power loss contributions of a DCT with wet clutches, and their relative significance along a set of driving cycles. Based on these results, a novel hybridised AMT (HAMT with a single dry clutch and an electric motor is proposed for the same vehicle. The HAMT architecture combines the high mechanical efficiency typical of AMTs with a single dry clutch, with the torque-fill capability and operational flexibility allowed by the electric motor. The measured efficiency maps of a case study DCT and HAMT are compared. This is then complemented by the analysis of the respective fuel consumption along the driving cycles, which is simulated with an experimentally validated vehicle model. In its internal combustion engine mode, the HAMT reduces fuel consumption by >9% with respect to the DCT.

  4. Egg clutch dehydration induces early hatching in red-eyed treefrogs, Agalychnis callidryas

    Directory of Open Access Journals (Sweden)

    María José Salica

    2017-07-01

    Full Text Available Terrestrial eggs have evolved repeatedly in tropical anurans exposing embryos to the new threat of dehydration. Red-eyed treefrogs, Agalychnis callidryas, lay eggs on plants over water. Maternally provided water allows shaded eggs in humid sites to develop to hatching without rainfall, but unshaded eggs and those in less humid sites can die from dehydration. Hatching responses of amphibian eggs to dry conditions are known from two lineages with independent origins of terrestrial eggs. Here, we experimentally tested for dehydration-induced early hatching in another lineage (Agalychnis callidryas, Phyllomedusidae, representing a third independent origin of terrestrial eggs. We also investigated how dehydration affected egg and clutch structure, and egg mortality. We collected clutches from a pond in Gamboa, Panama, and randomly allocated them to wet or dry treatments at age 1 day. Embryos hatched earlier from dry clutches than from wet clutches, accelerating hatching by ∼11%. Clutch thickness and egg diameter were affected by dehydration, diverging between treatments over time. Meanwhile, mortality in dry clutches was six-fold higher than in control clutches. With this study, early hatching responses to escape mortality from egg dehydration are now known from three anuran lineages with independent origins of terrestrial eggs, suggesting they may be widespread. Further studies are needed to understand how terrestrial amphibian eggs can respond to, or will be affected by, rapid changes in climate over the next decades.

  5. Computing eigenvalue sensitivity coefficients to nuclear data based on the CLUTCH method with RMC code

    International Nuclear Information System (INIS)

    Qiu, Yishu; She, Ding; Tang, Xiao; Wang, Kan; Liang, Jingang

    2016-01-01

    Highlights: • A new algorithm is proposed to reduce memory consumption for sensitivity analysis. • The fission matrix method is used to generate adjoint fission source distributions. • Sensitivity analysis is performed on a detailed 3D full-core benchmark with RMC. - Abstract: Recently, there is a need to develop advanced methods of computing eigenvalue sensitivity coefficients to nuclear data in the continuous-energy Monte Carlo codes. One of these methods is the iterated fission probability (IFP) method, which is adopted by most of Monte Carlo codes of having the capabilities of computing sensitivity coefficients, including the Reactor Monte Carlo code RMC. Though it is accurate theoretically, the IFP method faces the challenge of huge memory consumption. Therefore, it may sometimes produce poor sensitivity coefficients since the number of particles in each active cycle is not sufficient enough due to the limitation of computer memory capacity. In this work, two algorithms of the Contribution-Linked eigenvalue sensitivity/Uncertainty estimation via Tracklength importance CHaracterization (CLUTCH) method, namely, the collision-event-based algorithm (C-CLUTCH) which is also implemented in SCALE and the fission-event-based algorithm (F-CLUTCH) which is put forward in this work, are investigated and implemented in RMC to reduce memory requirements for computing eigenvalue sensitivity coefficients. While the C-CLUTCH algorithm requires to store concerning reaction rates of every collision, the F-CLUTCH algorithm only stores concerning reaction rates of every fission point. In addition, the fission matrix method is put forward to generate the adjoint fission source distribution for the CLUTCH method to compute sensitivity coefficients. These newly proposed approaches implemented in RMC code are verified by a SF96 lattice model and the MIT BEAVRS benchmark problem. The numerical results indicate the accuracy of the F-CLUTCH algorithm is the same as the C-CLUTCH

  6. Evolution of parental incubation behaviour in dinosaurs cannot be inferred from clutch mass in birds.

    Science.gov (United States)

    Birchard, Geoffrey F; Ruta, Marcello; Deeming, D Charles

    2013-08-23

    A recent study proposed that incubation behaviour (i.e. type of parental care) in theropod dinosaurs can be inferred from an allometric analysis of clutch volume in extant birds. However, the study in question failed to account for factors known to affect egg and clutch size in living bird species. A new scaling analysis of avian clutch mass demonstrates that type of parental care cannot be distinguished by conventional allometry because of the confounding effects of phylogeny and hatchling maturity. Precociality of young but not paternal care in the theropod ancestors of birds is consistent with the available data.

  7. Current Best Practices for Preventing Asbestos Exposure Among Brake and Clutch Repair Workers

    Science.gov (United States)

    Covers concerns about asbestos exposure for mechanics, how to tell if asbestos brake or clutch components contain asbestos, work practices to follow, protecting yourself for home mechanics, disposal of waste that contains asbestos.

  8. Detection technology research on the one-way clutch of automatic brake adjuster

    Science.gov (United States)

    Jiang, Wensong; Luo, Zai; Lu, Yi

    2013-10-01

    In this article, we provide a new testing method to evaluate the acceptable quality of the one-way clutch of automatic brake adjuster. To analysis the suitable adjusting brake moment which keeps the automatic brake adjuster out of failure, we build a mechanical model of one-way clutch according to the structure and the working principle of one-way clutch. The ranges of adjusting brake moment both clockwise and anti-clockwise can be calculated through the mechanical model of one-way clutch. Its critical moment, as well, are picked up as the ideal values of adjusting brake moment to evaluate the acceptable quality of one-way clutch of automatic brake adjuster. we calculate the ideal values of critical moment depending on the different structure of one-way clutch based on its mechanical model before the adjusting brake moment test begin. In addition, an experimental apparatus, which the uncertainty of measurement is ±0.1Nm, is specially designed to test the adjusting brake moment both clockwise and anti-clockwise. Than we can judge the acceptable quality of one-way clutch of automatic brake adjuster by comparing the test results and the ideal values instead of the EXP. In fact, the evaluation standard of adjusting brake moment applied on the project are still using the EXP provided by manufacturer currently in China, but it would be unavailable when the material of one-way clutch changed. Five kinds of automatic brake adjusters are used in the verification experiment to verify the accuracy of the test method. The experimental results show that the experimental values of adjusting brake moment both clockwise and anti-clockwise are within the ranges of theoretical results. The testing method provided by this article vividly meet the requirements of manufacturer's standard.

  9. Ergonomic assessment of drivers in MF285 and MF399 tractors during clutching using algometer

    OpenAIRE

    Hossein Fallahi; Mohammad Hossein Abbaspour-Fard; Amin Azhari; Mehdi Khojastehpour; Amin Nikkhah

    2016-01-01

    Tractor as one of the most widely used agricultural machinery should be considered from different aspects. The frequent application of clutch and brake pedals and also the steering wheel within farms, along with the unfavorable working conditions, cause negative effects on the occupational health of the tractor drivers. Thus, in this research, the imposed forces on three engaged muscles including: Gastrocnemius, Trapezius and Quadrate’s lumborum of the tractor drivers during clutching have be...

  10. Peculiarities of Clutch Forming Rails and Wheel Block Construction

    Science.gov (United States)

    Shiler, V. V.; Galiev, I. I.; Shiler, A. V.

    2018-03-01

    The clutch of the wheel and rail is significantly influenced by the design features of the standard wheel pair, which are manifested in the presence of "parasitic" slipping of the wheels along the rails during its movement. The purpose of the presented work is to evaluate new design solutions for wheel sets. The research was carried out using methods of comparative simulation modelling and physical prototyping. A new design of the wheel pair (block wheel pair) is proposed, which features an independent rotation of all surfaces of the wheels in contact with the rails. The block construction of the wheel pair forms open mechanical contours with the track gauge, which completely eliminates the "parasitic" slippage. As a result, in the process of implementing traction or braking forces, the coupling coefficient of the block construction of the wheel pair is significantly higher than that of existing structures. In addition, in the run-out mode, the resistance to movement of the block wheel pair is half as much. All this will allow one to significantly reduce the energy consumption for traction of trains, wear of track elements and crew, and to increase the speed and safety of train traffic.

  11. Development of a novel two-layer multiplate magnetorheological clutch for high-power applications

    International Nuclear Information System (INIS)

    Wang, Daoming; Tian, Zuzhi; Meng, Qingrui; Hou, Youfu

    2013-01-01

    A novel magnetorheological (MR) clutch for high-power applications is designed, simulated and tested. The clutch is implemented in a two-layer multiplate transmission form and adopts a two-way liquid cooling method to improve the heat dissipation capability. In this paper, a brief introduction to the transmission form of the proposed MR clutch is given first. Then, theoretical analyses of the output torque, magnetic circuit and temperature characteristic are conducted and further design details are presented and discussed, followed by a magnetostatic simulation of the designed circuit. A prototype of the clutch was fabricated and several tests were carried out to evaluate the torque transmission, time response and steady slip power of the prototype. The results show that the proposed MR clutch can produce a maximum output torque of 1545 N m and possesses a high steady slip power of up to 35 kW. Therefore, the developed two-layer multiplate MR clutch is promising for applications in many high-power situations. (paper)

  12. Environmental influences on egg and clutch sizes in lentic- and lotic-breeding salamanders

    Directory of Open Access Journals (Sweden)

    Jon M. Davenport

    2010-12-01

    Full Text Available Recent research indicates that social and environmental factors influence egg and clutch sizes in amphibians. However, most of this work is based on the reproductively diverse order Anura (frogs and toads, whereas less research has been conducted on Caudata (salamanders and Gymnophiona (caecilians. Researchers have suggested that a relationship exists between social and environmental factors and egg and clutch sizes in salamanders, but studies controlling for phylogenetic context are lacking. We could not identify a sufficient number of comparisons for social influences on egg and clutch sizes; therefore, we focused on environmental influences for this study. Data on egg size, clutch size, environmental factors, and phylogenies for salamanders were assembled from the scientific literature. We used independent, pair-wise comparisons to investigate the association of larval salamander habitat and egg size and the association of larval salamander habitat with clutch sizes within a phylogenetic framework. There is a significant association between larval habitat and egg size; specifically, stream-breeding species produce larger eggs. There is no significant association between larval habitat and clutchsize. Our study confirms earlier reports that salamander egg size is associated with larval environments, but is the first to use phylogenetically independent contrasts to account for the lack of phylogenetic independence of the traits measured (egg size and clutch size associated with many of the diverse lineages. Our study shows that environmental selection pressure can be quite strong on one aspect of salamander reproduction—egg size.

  13. Predictive Reliability Assessment of the Automatic Clutch on a Primary Sodium Pump Drive

    International Nuclear Information System (INIS)

    Westwell, P.

    1975-01-01

    This paper examines the reliability of a group of three clutch couplings each mounted between a pony motor and the main drive for the primary sodium pumps. The sodium pumps specification requires that continuously running AC pony motors be fitted to give a guaranteed 10% drive to the pumps in the event of a main supply failure. The drive to the main shaft is via 3 : 1 reduction gearing such that a six pole pony motor running at 300 rpm would drive the main shaft at 100 rpm i.e., 10% of its rated speed. In order that the pony motor drive could be permanently energised during normal operation a free wheeling clutch is fitted between the motor and the reduction gearing. The type of clutch chosen is. the Synchro-Self Shifting (SSS) clutch, shown in Figure 1. This type of clutch has proved itself under fairly onerous operating conditions, but is normally mounted on a horizontal driving shaft whereas in this case because of space limitations, it is necessary to mount it vertically. The reliability target set is that the chance of losing all three independent back-up pony motor drives on loss of main supplies should fall within the 10 -5 - 10 -6 band. Since the electrical supplies and other parts of the pony motor drives have been assessed within this target and some doubts expressed about the clutch it was now necessary to look at this in some detail

  14. Variation in clutch size in relation to nest size in birds.

    Science.gov (United States)

    Møller, Anders P; Adriaensen, Frank; Artemyev, Alexandr; Bańbura, Jerzy; Barba, Emilio; Biard, Clotilde; Blondel, Jacques; Bouslama, Zihad; Bouvier, Jean-Charles; Camprodon, Jordi; Cecere, Francesco; Charmantier, Anne; Charter, Motti; Cichoń, Mariusz; Cusimano, Camillo; Czeszczewik, Dorota; Demeyrier, Virginie; Doligez, Blandine; Doutrelant, Claire; Dubiec, Anna; Eens, Marcel; Eeva, Tapio; Faivre, Bruno; Ferns, Peter N; Forsman, Jukka T; García-Del-Rey, Eduardo; Goldshtein, Aya; Goodenough, Anne E; Gosler, Andrew G; Góźdź, Iga; Grégoire, Arnaud; Gustafsson, Lars; Hartley, Ian R; Heeb, Philipp; Hinsley, Shelley A; Isenmann, Paul; Jacob, Staffan; Järvinen, Antero; Juškaitis, Rimvydas; Korpimäki, Erkki; Krams, Indrikis; Laaksonen, Toni; Leclercq, Bernard; Lehikoinen, Esa; Loukola, Olli; Lundberg, Arne; Mainwaring, Mark C; Mänd, Raivo; Massa, Bruno; Mazgajski, Tomasz D; Merino, Santiago; Mitrus, Cezary; Mönkkönen, Mikko; Morales-Fernaz, Judith; Morin, Xavier; Nager, Ruedi G; Nilsson, Jan-Åke; Nilsson, Sven G; Norte, Ana C; Orell, Markku; Perret, Philippe; Pimentel, Carla S; Pinxten, Rianne; Priedniece, Ilze; Quidoz, Marie-Claude; Remeš, Vladimir; Richner, Heinz; Robles, Hugo; Rytkönen, Seppo; Senar, Juan Carlos; Seppänen, Janne T; da Silva, Luís P; Slagsvold, Tore; Solonen, Tapio; Sorace, Alberto; Stenning, Martyn J; Török, János; Tryjanowski, Piotr; van Noordwijk, Arie J; von Numers, Mikael; Walankiewicz, Wiesław; Lambrechts, Marcel M

    2014-09-01

    Nests are structures built to support and protect eggs and/or offspring from predators, parasites, and adverse weather conditions. Nests are mainly constructed prior to egg laying, meaning that parent birds must make decisions about nest site choice and nest building behavior before the start of egg-laying. Parent birds should be selected to choose nest sites and to build optimally sized nests, yet our current understanding of clutch size-nest size relationships is limited to small-scale studies performed over short time periods. Here, we quantified the relationship between clutch size and nest size, using an exhaustive database of 116 slope estimates based on 17,472 nests of 21 species of hole and non-hole-nesting birds. There was a significant, positive relationship between clutch size and the base area of the nest box or the nest, and this relationship did not differ significantly between open nesting and hole-nesting species. The slope of the relationship showed significant intraspecific and interspecific heterogeneity among four species of secondary hole-nesting species, but also among all 116 slope estimates. The estimated relationship between clutch size and nest box base area in study sites with more than a single size of nest box was not significantly different from the relationship using studies with only a single size of nest box. The slope of the relationship between clutch size and nest base area in different species of birds was significantly negatively related to minimum base area, and less so to maximum base area in a given study. These findings are consistent with the hypothesis that bird species have a general reaction norm reflecting the relationship between nest size and clutch size. Further, they suggest that scientists may influence the clutch size decisions of hole-nesting birds through the provisioning of nest boxes of varying sizes.

  15. Clutch morphology and the timing of exposure impact the susceptibility of aquatic insect eggs to esfenvalerate.

    Science.gov (United States)

    Palmquist, Katherine R; Jenkins, Jeffrey J; Jepson, Paul C

    2008-08-01

    We investigated Baetis spp. (mayfly), Hesperoperla pacifica (stonefly), and Brachycentrus americanus (caddisfly) susceptibility at the egg stage to esfenvalerate, a synthetic pyrethroid insecticide. Eggs were obtained from the field or from field-collected gravid females at sites near Corvallis (OR, USA) and the Metolius River at Camp Sherman (OR, USA) for static exposures under controlled conditions for temperature and light. Eggs were exposed to esfenvalerate for 48 h at concentrations ranging from 0.025 to 4.0 microg/L. No effect on mortality or posthatch growth was detected in H. pacifica eggs exposed to esfenvalerate concentrations up to 1.0 microg/L. Exposure to 0.07 microg/L of esfenvalerate, however, caused a significant increase in Baetis spp. egg mortality, and exposure of near-eclosion eggs to lower concentrations (0.025 and 0.05 microg/L) resulted in behavioral effects and reduced survivorship in newly hatched Baetis nymphs. Early stage B. americanus eggs were 10-fold more sensitive to esfenvalerate when removed from the gelatinous clutch before exposure, an indication that the gelatin affords protection from toxicant exposure. Exposures of near-hatch B. americanus clutches to esfenvalerate concentrations ranging between 0.035 and 0.2 microg/L, however, resulted in significant clutch death within clutches resulting from behavioral aberrations of first-instar larvae. The results of the present study suggest that aquatic insect egg clutch morphology can be a strong influence on susceptibility of embryos to esfenvalerate exposure.

  16. Beyond size–number trade-offs: clutch size as a maternal effect

    Science.gov (United States)

    Brown, Gregory P.; Shine, Richard

    2009-01-01

    Traditionally, research on life-history traits has viewed the link between clutch size and offspring size as a straightforward linear trade-off; the product of these two components is taken as a measure of maternal reproductive output. Investing more per egg results in fewer but larger eggs and, hence, offspring. This simple size–number trade-off has proved attractive to modellers, but our experimental studies on keelback snakes (Tropidonophis mairii, Colubridae) reveal a more complex relationship between clutch size and offspring size. At constant water availability, the amount of water taken up by a snake egg depends upon the number of adjacent eggs. In turn, water uptake affects hatchling size, and therefore an increase in clutch size directly increases offspring size (and thus fitness under field conditions). This allometric advantage may influence the evolution of reproductive traits such as growth versus reproductive effort, optimal age at female maturation, the body-reserve threshold required to initiate reproduction and nest-site selection (e.g. communal oviposition). The published literature suggests that similar kinds of complex effects of clutch size on offspring viability are widespread in both vertebrates and invertebrates. Our results also challenge conventional experimental methodologies such as split-clutch designs for laboratory incubation studies: by separating an egg from its siblings, we may directly affect offspring size and thus viability. PMID:19324614

  17. Count your eggs before they invade: identifying and quantifying egg clutches of two invasive apple snail species (Pomacea.

    Directory of Open Access Journals (Sweden)

    Colin H Kyle

    Full Text Available Winning the war against invasive species requires early detection of invasions. Compared to terrestrial invaders, aquatic species often thrive undetected under water and do not garner notice until too late for early action. However, fortunately for managers, apple snails (Family Ampullariidae, Genus Pomacea provide their own conspicuous sign of invasion in the form of vibrantly colored egg clutches. Managers can potentially use egg clutches laid in the riparian zone as a means of early detection and species identification. To facilitate such efforts, we quantified differences in characteristics (length, width, depth, mass, egg number of field-laid clutches for the two most common invasive species of apple snail, P. canaliculata and P. maculata, in native and non-native populations. Pomacea canaliculata native and non-native populations differed noticeably only in width. Native P. maculata clutches possessed significantly greater width, mass and eggs numbers compared with native P. canaliculata. Non-native P. maculata clutches significantly exceeded all other populations in all measured characteristics. Consequently, these traits may successfully distinguish between species. Fecundity data also allowed us to develop models that accurately estimated the number of eggs per clutch for each species based on clutch dimensions. We tested one, two and three dimensional models of clutches, including rendering a clutch as either a complete ellipsoid or an ellipsoid intersected by a cylinder to represent the oviposition site. Model comparisons found the product of length and depth, with a different function for each population, best predicted egg number for both species. Comparisons of egg number to clutch volume and mass implied non-native P. canaliculata may be food limited, while non-native P. maculata appeared to produce such enormous clutches by having access to greater nutrients than the native population. With these new tools, researchers and

  18. Clutch pressure estimation for a power-split hybrid transmission using nonlinear robust observer

    Science.gov (United States)

    Zhou, Bin; Zhang, Jianwu; Gao, Ji; Yu, Haisheng; Liu, Dong

    2018-06-01

    For a power-split hybrid transmission, using the brake clutch to realize the transition from electric drive mode to hybrid drive mode is an available strategy. Since the pressure information of the brake clutch is essential for the mode transition control, this research designs a nonlinear robust reduced-order observer to estimate the brake clutch pressure. Model uncertainties or disturbances are considered as additional inputs, thus the observer is designed in order that the error dynamics is input-to-state stable. The nonlinear characteristics of the system are expressed as the lookup tables in the observer. Moreover, the gain matrix of the observer is solved by two optimization procedures under the constraints of the linear matrix inequalities. The proposed observer is validated by offline simulation and online test, the results have shown that the observer achieves significant performance during the mode transition, as the estimation error is within a reasonable range, more importantly, it is asymptotically stable.

  19. Lubricant flow analysis for effective lubrication of tractor forward/reverse clutch

    Directory of Open Access Journals (Sweden)

    Daekyung Noh

    2017-04-01

    Full Text Available Owing to the high power requirements of tractors, their low-power transmission gears often experience durability problems such as burning of the clutch. The operation of tractors under high load conditions also causes clutch slip, with the consequent longer operation duration exacerbating the burning of the friction plate. Solving this problem requires effective lubricant distribution. This was achieved in the present study by the development of an analysis model for predicting the lubricant flow rate. The reliability of the model was verified by comparing its predictions for various operation conditions with experimental measurements. Using the model, it was determined that effective distribution of the lubricant could be achieved without significant modification of the system, by only adjusting the gaps between the clutch piston and the housing, and between the separation plates and the case. Keywords: Mechanical engineering

  20. Regional drivers of clutch loss reveal important trade-offs for beach-nesting birds.

    Science.gov (United States)

    Maslo, Brooke; Schlacher, Thomas A; Weston, Michael A; Huijbers, Chantal M; Anderson, Chris; Gilby, Ben L; Olds, Andrew D; Connolly, Rod M; Schoeman, David S

    2016-01-01

    Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small site scale. We examine survival of model shorebird clutches as an index of true clutch survival at a regional scale (∼200 km), encompassing a variety of geomorphologies, predator communities, and human use regimes in southeast Queensland, Australia. Of the 132 model nests deployed and monitored with cameras, 45 (34%) survived the experimental exposure period. Thirty-five (27%) were lost to flooding, 32 (24%) were depredated, nine (7%) buried by sand, seven (5%) destroyed by people, three (2%) failed by unknown causes, and one (1%) was destroyed by a dog. Clutch fate differed substantially among regions, particularly with respect to losses from flooding and predation. 'Topographic' exposure was the main driver of mortality of nests placed close to the drift line near the base of dunes, which were lost to waves (particularly during storms) and to a lesser extent depredation. Predators determined the fate of clutches not lost to waves, with the depredation probability largely influenced by region. Depredation probability declined as nests were backed by higher dunes and were placed closer to vegetation. This study emphasizes the scale at which clutch fate and survival varies within a regional context, the prominence of corvids as egg predators, the significant role of flooding as a source of nest loss, and the multiple trade-offs faced by beach-nesting birds and those that manage them.

  1. Regional drivers of clutch loss reveal important trade-offs for beach-nesting birds

    Directory of Open Access Journals (Sweden)

    Brooke Maslo

    2016-09-01

    Full Text Available Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small site scale. We examine survival of model shorebird clutches as an index of true clutch survival at a regional scale (∼200 km, encompassing a variety of geomorphologies, predator communities, and human use regimes in southeast Queensland, Australia. Of the 132 model nests deployed and monitored with cameras, 45 (34% survived the experimental exposure period. Thirty-five (27% were lost to flooding, 32 (24% were depredated, nine (7% buried by sand, seven (5% destroyed by people, three (2% failed by unknown causes, and one (1% was destroyed by a dog. Clutch fate differed substantially among regions, particularly with respect to losses from flooding and predation. ‘Topographic’ exposure was the main driver of mortality of nests placed close to the drift line near the base of dunes, which were lost to waves (particularly during storms and to a lesser extent depredation. Predators determined the fate of clutches not lost to waves, with the depredation probability largely influenced by region. Depredation probability declined as nests were backed by higher dunes and were placed closer to vegetation. This study emphasizes the scale at which clutch fate and survival varies within a regional context, the prominence of corvids as egg predators, the significant role of flooding as a source of nest loss, and the multiple trade-offs faced by beach-nesting birds and those that manage them.

  2. Studies on centrifugal clutch judder behavior and the design of frictional lining materials

    Science.gov (United States)

    Li, Tse-Chang; Huang, Yu-Wen; Lin, Jen-Fin

    2016-01-01

    This study examines the judder behavior of a centrifugal clutch from the start of hot spots in the conformal contact, then the repeated developments of thermoelastic instability, and finally the formation of cyclic undulations in the vibrations, friction coefficient and torque. This behavior is proved to be consistent with the testing results. Using the Taguchi method, 18 kinds of frictional lining specimens were prepared in order to investigate their performance in judder resistance and establish a relationship between judder behavior and the Ts/Td (Ts: static torque; Td: dynamic torque) and dμ/dVx (μ: friction coefficient; Vx: relative sliding velocity of frictional lining and clutch drum) parameters. These specimens are also provided to examine the effects and profitability with regard to the centrifugal clutch, and find the relative importance of the various control factors. Theoretical models for the friction coefficient (μ), the critical sliding velocity (Vc) with clutch judder, and the contact pressure ratio p* /pbar (p*: pressure undulation w.r.t. pbar; pbar: mean contact pressure) and temperature corresponding to judder behavior are developed. The parameters of the contact pressure ratio and temperature are shown to be helpful to explain the occurrence of judder. The frictional torque and the rotational speeds of the driveline, clutch, and clutch drum as functions of engagement time for 100 clutch cycles are obtained experimentally to evaluate dμ/dVx and Ts/Td. A sharp rise in the maximum p* /pbar occurred when the relative sliding velocity reached the critical velocity, Vc. An increase in the maximum p* /pbar generally led to an increase of the (initially negative) dμ/dVx value, and thus the severity of judder. The fluctuation intensity of dμ/dVx becomes a governing factor of the growth of dμ/dVx itself in the engagement process. The mean values of dμ/dVx and Ts/Td for the clutching tests with 100 cycles can be roughly divided into three groups

  3. Wheeled Vehicle Clutches, Transmissions, and Transfers. Military Curriculum Materials for Vocational and Technical Education.

    Science.gov (United States)

    Army Ordnance Center and School, Aberdeen Proving Ground, MD.

    This course is one of several subcourses that make up the entire Army correspondence course on wheeled vehicle maintenance. The subcourse is designed to provide the student with information about the operation, malfunction diagnosis, maintenance, and repair of wheeled vehicle clutches, transmissions, and transfer cases. It provides the basic…

  4. Clutch size and parental effort in the Great Tit Parus major

    NARCIS (Netherlands)

    Verhulst, S.; Tinbergen, J.M.

    1997-01-01

    We experimentally reduced clutch size of Great Tits Parus major to investigate the effects on parental care (including Daily Energy Expenditure, DEE, measured with doubly labelled water), and the relationship between DEE and the residual reproductive value. The length of a working day was not

  5. Multiple breeding in the Great Tit, II. The costs of rearing a second clutch

    NARCIS (Netherlands)

    Verhulst, S.

    1998-01-01

    1. Multiple breeding (raising more than one batch of young per breeding season) is a common life-history tactic, but little is known as yet of the accompanying costs and benefits. Second clutches of Great Tits, a facultative multiple breeder, were removed over three years to investigate the costs of

  6. Multiple breeding in the Great Tit, II. The costs of rearing a second clutch

    NARCIS (Netherlands)

    Verhulst, S

    1. Multiple breeding (raising more than one batch of young per breeding season) is a common life-history tactic, but little is known as yet of the accompanying costs and benefits. Second clutches of Great Tits, a facultative multiple breeder, were removed over three years to investigate the costs of

  7. Life-history and ecological correlates of geographic variation in egg and clutch mass among passerine species

    Science.gov (United States)

    Martin, T.E.; Bassar, R.D.; Bassar, S.K.; Fontaine, J.J.; Lloyd, P.; Mathewson, Heather A.; Niklison, Alina M.; Chalfoun, A.

    2006-01-01

    Broad geographic patterns in egg and clutch mass are poorly described, and potential causes of variation remain largely unexamined. We describe interspecific variation in avian egg and clutch mass within and among diverse geographic regions and explore hypotheses related to allometry, clutch size, nest predation, adult mortality, and parental care as correlates and possible explanations of variation. We studied 74 species of Passeriformes at four latitudes on three continents: the north temperate United States, tropical Venezuela, subtropical Argentina, and south temperate South Africa. Egg and clutch mass increased with adult body mass in all locations, but differed among locations for the same body mass, demonstrating that egg and clutch mass have evolved to some extent independent of body mass among regions. A major portion of egg mass variation was explained by an inverse relationship with clutch size within and among regions, as predicted by life-history theory. However, clutch size did not explain all geographic differences in egg mass; eggs were smallest in South Africa despite small clutch sizes. These small eggs might be explained by high nest predation rates in South Africa; life-history theory predicts reduced reproductive effort under high risk of offspring mortality. This prediction was supported for clutch mass, which was inversely related to nest predation but not for egg mass. Nevertheless, clutch mass variation was not fully explained by nest predation, possibly reflecting interacting effects of adult mortality. Tests of the possible effects of nest predation on egg mass were compromised by limited power and by counterposing direct and indirect effects. Finally, components of parental investment, defined as effort per offspring, might be expected to positively coevolve. Indeed, egg mass, but not clutch mass, was greater in species that shared incubation by males and females compared with species in which only females incubate eggs. However, egg and

  8. Dry Friction Clutch Disc of an Automobile under Transient Thermal Load: A Comparison of Friction Lining Materials

    Directory of Open Access Journals (Sweden)

    Ali Anosh

    2017-01-01

    Full Text Available This paper shows the comparison of temperatures produced in a dry friction clutch disc with different materials during a single engagement to assist in clutch plate design and analysis. A study of usage of different materials for friction lining of clutch disc is required, which will provide improved performance and enhanced life. This investigation is modelled mathematically and solved numerically using finite element method. ANSYS® 15.0 is a dedicated finite element package used for determining the temperature distribution across a clutch disc. In the present work, an investigation of a conventionally used harmful friction lining material asbestos is compared with carbon-carbon composite, S2-glass fibre and aluminium metal matrix composite. The transient thermal analysis of a clutch disc with different materials is performed and the temperature distribution on the clutch system is compared. Simulation results indicate that all the values of the temperature obtained from the analysis of aluminium metal matrix are less than those of asbestos based lining material, therefore clutch disc made up of aluminium metal matrix composite will assure the extended service life and the longer stability due to the fact that the temperature responsible for the wear and tear has been reduced. Furthermore, the slipping time is also considered in this investigation.

  9. Paternal care and male mate-attraction effort in the European starling is adjusted to clutch size.

    Science.gov (United States)

    Komdeur, Jan; Wiersma, Popko; Magrath, Michael

    2002-06-22

    In facultative polygynous birds with biparental care, a trade-off may occur between male parental care and attraction of additional mates. If there is a cost associated with reduced male parental care, the relative benefit of mate attraction may be predicted to decrease as the size of a male's clutch or brood increases. We tested this prediction in monogamous pairs of facultatively polygynous European starlings (Sturnus vulgaris). The larger the clutch, the more time the male spent incubating and the less time he spent attracting an additional female (i.e. singing near and carrying green nesting material into adjacent empty nest-boxes). Reduced paternal incubation resulted in lower overall incubation (the female did not compensate) and lower hatching success. Immediately after experimental reduction of clutches, males spent significantly less time incubating and more time singing and carrying greenery, and vice versa for experimentally enlarged clutches. Males with experimentally reduced clutches attracted a second female more often than males with experimentally enlarged clutches. This is the first study, to our knowledge, to provide experimental evidence for an adjustment of paternal care and male mate-attraction effort to clutch size. However, a trade-off between paternal nestling provisioning and mate attraction was not revealed, probably due to the absence of unpaired females by that time in the breeding season. Experiments showed that the relative contribution of the male and female to nestling provisioning was unrelated to brood size.

  10. Natural selection and inheritance of breeding time and clutch size in the collared flycatcher.

    Science.gov (United States)

    Sheldon, B C; Kruuk, L E B; Merilä, J

    2003-02-01

    Many characteristics of organisms in free-living populations appear to be under directional selection, possess additive genetic variance, and yet show no evolutionary response to selection. Avian breeding time and clutch size are often-cited examples of such characters. We report analyses of inheritance of, and selection on, these traits in a long-term study of a wild population of the collared flycatcher Ficedula albicollis. We used mixed model analysis with REML estimation ("animal models") to make full use of the information in complex multigenerational pedigrees. Heritability of laying date, but not clutch size, was lower than that estimated previously using parent-offspring regressions, although for both traits there was evidence of substantial additive genetic variance (h2 = 0.19 and 0.29, respectively). Laying date and clutch size were negatively genetically correlated (rA = -0.41 +/- 0.09), implying that selection on one of the traits would cause a correlated response in the other, but there was little evidence to suggest that evolution of either trait would be constrained by correlations with other phenotypic characters. Analysis of selection on these traits in females revealed consistent strong directional fecundity selection for earlier breeding at the level of the phenotype (beta = -0.28 +/- 0.03), but little evidence for stabilising selection on breeding time. We found no evidence that clutch size was independently under selection. Analysis of fecundity selection on breeding values for laying date, estimated from an animal model, indicated that selection acts directly on additive genetic variance underlying breeding time (beta = -0.20 +/- 0.04), but not on clutch size (beta = 0.03 +/- 0.05). In contrast, selection on laying date via adult female survival fluctuated in sign between years, and was opposite in sign for selection on phenotypes (negative) and breeding values (positive). Our data thus suggest that any evolutionary response to selection on

  11. Use of statistical models based on radiographic measurements to predict oviposition date and clutch size in rock iguanas (Cyclura nubila)

    International Nuclear Information System (INIS)

    Alberts, A.C.

    1995-01-01

    The ability to noninvasively estimate clutch size and predict oviposition date in reptiles can be useful not only to veterinary clinicians but also to managers of captive collections and field researchers. Measurements of egg size and shape, as well as position of the clutch within the coelomic cavity, were taken from diagnostic radiographs of 20 female Cuban rock iguanas, Cyclura nubila, 81 to 18 days prior to laying. Combined with data on maternal body size, these variables were entered into multiple regression models to predict clutch size and timing of egg laying. The model for clutch size was accurate to 0.53 ± 0.08 eggs, while the model for oviposition date was accurate to 6.22 ± 0.81 days. Equations were generated that should be applicable to this and other large Cyclura species. © 1995 Wiley-Liss, Inc

  12. Temperature and shear rate characteristics of electrorheological gel applied to a clutch

    International Nuclear Information System (INIS)

    Koyanagi, K; Takata, Y; Motoyoshi, T; Oshima, T; Kakinuma, Y; Anzai, H; Sakurai, K

    2013-01-01

    This investigation reports the physical characteristics of electrorheological (ER) gels, which are a type of functional material having controlled surface friction. We previously developed slip clutches using ER gels sandwiched between electrodes, and verified their responses and controllability. We newly report the temperature and shear rate characteristics of ER gel in this study because the input and output electrodes of the clutch continuously slip past each other. While the temperature of ER gels increased when energized, the shear stress hardly changed. Instead, wearing and adaptation to the electrode affect the property. The shear rate hardly affected the shear stress in the high-shear-rate region. Conversely, the shear stress depended on the shear rate in the lower region.

  13. DETERMINATION ANALYSIS OF TEMPERATURE REGIMES, FUNCTIONAL CHARACTERISTICS AND SLIDING CURVES OF A HYDRODYNAMIC CLUTCH

    Directory of Open Access Journals (Sweden)

    Božidar V Krstić

    2010-01-01

    Full Text Available Analysis of output quality of power transmitters is possible in position when characteristics are determined earlier. This is the reason why we focused on determination of these characteristics for a concrete power hydro-transmitter. This means that the investigation task primarily consisted of determination of functional characteristics, defining of the sliding curves and temperature regimes of a concrete hydrodynamic clutch. Results of velocity and pressure field investigations in the working space of this clutch, obtained by use of the same test setup, are the basis for determination and analysis of the functional characteristics, sliding curves and temperature regimes. In this work we also analyzed function of the hydrodynamic transmitter in assembly with an internal combustion engine, as well as a process of acceleration and deceleration of a vehicle with this assembly in it.

  14. Design and control of electromagnetic clutch actuation system for automated manual transmission

    Science.gov (United States)

    Ranjan, Ashish; Prasanth, S.; Cherian, Fenin; Baskar, P.

    2017-11-01

    There is a growing interest towards Automatic Transmission in India as it provides better comfort and drivability. But the high cost of this system is limiting itself to be successful in the Indian markets. Due to this, Automated Manual Transmission (AMT) is considered which provides a better solution towards automation as it enhances the drivability and fuel consumption characteristics of a manual transmission at lower costs. However, torque lag and comfort are major issues with AMT which can be addressed by reducing the shift time. In this paper we describe an Electromagnetic Linear Clutch Actuator as a replacement to current electrohydraulic and electromechanical actuator. A control system for the actuator is presented and a clutch engagement strategy is also implemented which reduces the engagement time to 0.78 seconds while reducing jerk and torque lag. The actuator and control system is simulated on a MATLAB Simulink and agreeable results have been obtained.

  15. Torque Control of a Rehabilitation Teaching Robot Using Magneto-Rheological Fluid Clutches

    Science.gov (United States)

    Hakogi, Hokuto; Ohaba, Motoyoshi; Kuramochi, Naimu; Yano, Hidenori

    A new robot that makes use of MR-fluid clutches for simulating torque is proposed to provide an appropriate device for training physical therapy students in knee-joint rehabilitation. The feeling of torque provided by the robot is expected to correspond to the torque performance obtained by physical therapy experts in a clinical setting. The torque required for knee-joint rehabilitation, which is a function of the rotational angle and the rotational angular velocity of a knee movement, is modeled using a mechanical system composed of typical spring-mass-damper elements. The robot consists of two MR-fluid clutches, two induction motors, and a feedback control system. In the torque experiments, output torque is controlled using the spring and damper coefficients separately. The values of these coefficients are determined experimentally. The experimental results show that the robot would be suitable for training physical therapy students to experience similar torque feelings as needed in a clinical situation.

  16. Simulation model of an electrohydraulic-actuated double-clutch transmission vehicle: modelling and system design

    Science.gov (United States)

    Schoeftner, J.; Ebner, W.

    2017-12-01

    Automated and manual transmissions are the main link between engine and powertrain. The technical term when the transmission provides the desired torque during all possible driving conditions is denoted as powertrain matching. Recent developments in the last years show that double-clutch-transmissions (DCTs) are a reasonable compromise in terms of production costs, shifting quality, drivability and fuel efficiency. They have several advantages compared to other automatic transmissions (AT). Most DCTs nowadays consist of a hydraulic actuation control unit, which controls the clutches of the gearbox in order to induce a desired drivetrain torque into the driveline. The main functions of hydraulic systems are manifold: they initiate gear shifts, they provide sufficient oil for lubrication and they control the shift quality by suitably providing a desired oil flow or pressure for the clutch actuation. In this paper, a mathematical model of a passenger car equipped with a DCT is presented. The objective of this contribution is to get an increased understanding for the dynamics of the hydraulic circuit and its coupling to the vehicle drivetrain. The simulation model consists of a hydraulic and a mechanical domain: the hydraulic actuation circuit is described by nonlinear differential equations and includes the dynamics of the line pressure and the proportional valve, as well as the influence of the pressure reducing valve, pipe resistances and accumulator dynamics. The drivetrain with its gear ratios, moments of inertia, torsional stiffness of the rotating shafts and a simple longitudinal vehicle model represent the mechanical domain. The link between hydraulic and mechanical domain is given by the clutch, which combines hydraulic equations and Newton's laws. The presented mathematical model may not only be used as a simulation model for developing the transmission control software, it may also serve as a virtual layout for the design process phase. At the end of this

  17. Variation in clutch size in relation to nest size in birds

    OpenAIRE

    Moller Anders P.; Adriaensen Frank; Artemyev Alexandr; Banbura Jerzy; Barba Emilio; Biard Clotilde; Blondel Jacques; Bouslama Zihad; Bouvier Jean-Charles; Camprodon Jordi; Cecere Francesco; Charmantier Anne; Charter Motti; Cichon Mariusz; Cusimano Camillo

    2014-01-01

    © 2014 The Authors. Nests are structures built to support and protect eggs and/or offspring from predators, parasites, and adverse weather conditions. Nests are mainly constructed prior to egg laying, meaning that parent birds must make decisions about nest site choice and nest building behavior before the start of egg-laying. Parent birds should be selected to choose nest sites and to build optimally sized nests, yet our current understanding of clutch size-nest size relationships is limited...

  18. Condition-dependent clutch desertion in Great Tit (Parus major) females subjected to human disturbance

    OpenAIRE

    2011-01-01

    Abstract Nest desertion behaviour in relation to body condition and timing of breeding was studied in Great Tit (Parus major) females during two breeding seasons. Desertion, most likely unintentionally provoked by catching females during the incubation period, occurred at a very high rate with 41.2 and 25.6% of deserted first clutches in the two study years. The association between desertion probability, body condition (index calculated as residuals from the regression of body mass...

  19. Volume of eggs in the clutches of Grass snake Natrix natrix and Dice snake N. tessellata: error correction

    Directory of Open Access Journals (Sweden)

    Klenina Anastasiya Aleksandrovna

    2015-12-01

    Full Text Available The authors have made a mistake in calculating the volume of eggs in the clutches of snake family Natrix. In this article we correct the error. As a result, it was revealed, that the volume of eggs positively correlates with a female length and its mass, as well as with the quantity of eggs in the clutches. There is a positive correlation between the characteristics of newborn snakes (length and mass and the volume of eggs, from which they hatched.

  20. Infanticide and within-clutch competition select for reproductive synchrony in a cooperative bird.

    Science.gov (United States)

    Riehl, Christina

    2016-08-01

    Reproduction among members of social animal groups is often highly synchronized, but neither the selective advantages nor the proximate causes of synchrony are fully understood. Here I investigate the evolution of hatching synchrony in the Greater Ani (Crotophaga major), a communally nesting bird in which several unrelated females contribute eggs to a large, shared clutch. Hatching synchrony is variable, ranging from complete synchrony to moderate asynchrony, and is determined by the onset of incubation of the communal clutch. Data from a 10-year field study indicate that individual reproductive success is highest in synchronous groups, and that nestlings that hatch in the middle of the hatching sequence are most likely to survive. Nestling mortality is high in asynchronous clutches because early-hatching nestlings are more likely to be killed by adult group members, whereas late-hatching nestlings are more likely to starve due competition with their older nest-mates. Therefore, the timing of hatching appears to be under stabilizing selection from infanticide and resource competition acting in concert. These results provide empirical support for models predicting that synchrony may evolve as an adaptive counter-strategy to infanticide, and they highlight the importance of competition in shaping the timing of reproduction in social groups. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  1. Dynamic Temperature Rise Mechanism and Some Controlling Factors of Wet Clutch Engagement

    Directory of Open Access Journals (Sweden)

    Zhang Zhigang

    2016-01-01

    Full Text Available The friction transmission model of wet clutch is established to analyze the friction transmission mechanism of its engagement. The model is developed by applying both the average flow model and the elastic contact model between the friction disk and separator plate. The key components during wet clutch engagement are the separator plate, friction disk, and lubricant. The one-dimension transient models of heat transfer in radial direction for the three components are built on the basis of the heat transfer theory and the conservation law of energy. The friction transmission model and transient heat transfer models are coupled and solved by using the Runge-Kutta numerical method, and the radial temperature distribution and their detailed parametric study for the three components are conducted separately. The simulation results show that the radial temperature for the three components rises with the increase of radius in engagement. The changes in engagement pressure, lubricant viscosity, friction lining permeability, combined surface roughness RMS, equivalent elasticity modulus, difference between dynamic and static friction coefficients, and lubricant flow have important influence on the temperature rise characteristics. The proposed models can get better understanding of the dynamic temperature rise characteristics of wet clutch engagement.

  2. Optimal control of the gear shifting process for shift smoothness in dual-clutch transmissions

    Science.gov (United States)

    Li, Guoqiang; Görges, Daniel

    2018-03-01

    The control of the transmission system in vehicles is significant for the driving comfort. In order to design a controller for smooth shifting and comfortable driving, a dynamic model of a dual-clutch transmission is presented in this paper. A finite-time linear quadratic regulator is proposed for the optimal control of the two friction clutches in the torque phase for the upshift process. An integral linear quadratic regulator is introduced to regulate the relative speed difference between the engine and the slipping clutch under the optimization of the input torque during the inertia phase. The control objective focuses on smoothing the upshift process so as to improve the driving comfort. Considering the available sensors in vehicles for feedback control, an observer design is presented to track the immeasurable variables. Simulation results show that the jerk can be reduced both in the torque phase and inertia phase, indicating good shift performance. Furthermore, compared with conventional controllers for the upshift process, the proposed control method can reduce shift jerk and improve shift quality.

  3. Evolution of avian clutch size along latitudinal gradients: do seasonality, nest predation or breeding season length matter?

    Science.gov (United States)

    Griebeler, E M; Caprano, T; Böhning-Gaese, K

    2010-05-01

    Birds display a latitudinal gradient in clutch size with smaller clutches in the tropics and larger in the temperate region. Three factors have been proposed to affect this pattern: seasonality of resources (SR), nest predation and length of the breeding season (LBS). Here, we test the importance of these factors by modelling clutch size evolution within bird populations under different environmental settings. We use an individual-based ecogenetic simulation model that combines principles from population ecology and life history theory. Results suggest that increasing SR from the tropics to the poles by itself or in combination with a decreasing predation rate and LBS can generate the latitudinal gradient in clutch size. Annual fecundity increases and annual adult survival rate decreases from the tropics to the poles. We further show that the annual number of breeding attempts that (together with clutch size) determines total annual egg production is an important trait to understand latitudinal patterns in these life history characteristics. Field experiments that manipulate environmental factors have to record effects not only on clutch size, but also on annual number of breeding attempts. We use our model to predict the outcome of such experiments under different environmental settings.

  4. Different temperature and cooling patterns at the blunt and sharp egg poles reflect the arrangement of eggs in an avian clutch.

    Science.gov (United States)

    Šálek, Miroslav E; Zárybnická, Markéta

    2015-01-01

    Incubation is an energetically demanding process during which birds apply heat to their eggs to ensure embryonic development. Parent behaviours such as egg turning and exchanging the outer and central eggs in the nest cup affect the amount of heat lost to the environment from individual eggs. Little is known, however, about whether and how egg surface temperature and cooling rates vary among the different areas of an egg and how the arrangement of eggs within the clutch influences heat loss. We performed laboratory (using Japanese quail eggs) and field (with northern lapwing eggs) experiments using infrared imaging to assess the temperature and cooling patterns of heated eggs and clutches. We found that (i) the sharp poles of individual quail eggs warmed to a higher egg surface temperature than did the blunt poles, resulting in faster cooling at the sharp poles compared to the blunt poles; (ii) both quail and lapwing clutches with the sharp poles oriented towards the clutch centre (arranged clutches) maintained higher temperatures over the central part of the clutch than occurred in those clutches where most of the sharp egg poles were oriented towards the exterior (scattered clutches); and (iii) the arranged clutches of both quail and lapwing showed slower cooling rates at both the inner and outer clutch positions than did the respective parts of scattered clutches. Our results demonstrate that egg surface temperature and cooling rates differ between the sharp and blunt poles of the egg and that the orientation of individual eggs within the nest cup can significantly affect cooling of the clutch as a whole. We suggest that birds can arrange their eggs within the nest cup to optimise thermoregulation of the clutch.

  5. Performance Investigation of A Mix Wind Turbine Using A Clutch Mechanism At Low Wind Speed Condition

    Science.gov (United States)

    Jamanun, M. J.; Misaran, M. S.; Rahman, M.; Muzammil, W. K.

    2017-07-01

    Wind energy is one of the methods that generates energy from sustainable resources. This technology has gained prominence in this era because it produces no harmful product to the society. There is two fundamental type of wind turbine are generally used this day which is Horizontal axis wind turbine (HAWT) and Vertical axis wind turbine (VAWT). The VAWT technology is more preferable compare to HAWT because it gives better efficiency and cost effectiveness as a whole. However, VAWT is known to have distinct disadvantage compared to HAWT; self-start ability and efficiency at low wind speed condition. Different solution has been proposed to solve these issues which includes custom design blades, variable angle of attack mechanism and mix wind turbine. A new type of clutch device was successfully developed in UMS to be used in a mix Savonius-Darrieus wind turbine configuration. The clutch system which barely audible when in operation compared to a ratchet clutch system interconnects the Savonius and Darrieus rotor; allowing the turbine to self-start at low wind speed condition as opposed to a standalone Darrieus turbine. The Savonius height were varied at three different size in order to understand the effect of the Savonius rotor to the mix wind turbine performance. The experimental result shows that the fabricated Savonius rotor show that the height of the Savonius rotor affecting the RPM for the turbine. The swept area (SA), aspect ratio (AR) and tip speed ratio (TSR) also calculated in this paper. The highest RPM recorded in this study is 90 RPM for Savonius rotor 0.22-meter height at 2.75 m/s. The Savonius rotor 0.22-meter also give the highest TSR for each range of speed from 0.75 m/s, 1.75 m/s and 2.75 m/s where it gives 1.03 TSR, 0.76 TSR, and 0.55 TSR.

  6. Fuzzy Determination of Target Shifting Time and Torque Control of Shifting Phase for Dry Dual Clutch Transmission

    Directory of Open Access Journals (Sweden)

    Zhiguo Zhao

    2014-01-01

    Full Text Available Based on the independently developed five-speed dry dual clutch transmission (DDCT, the paper proposes the torque coordinating control strategy between engine and two clutches, which obtains engine speed and clutch transferred torque in the shifting process, adequately reflecting the driver intention and improving the shifting quality. Five-degree-of-freedom (DOF shifting dynamics model of DDCT with single intermediate shaft is firstly established according to its physical characteristics. Then the quantitative control objectives of the shifting process are presented. The fuzzy decision of shifting time and the model-based torque coordinating control strategy are proposed and also verified by simulating under different driving intentions in up-/downshifting processes with the DCT model established on the MATLAB/Simulink. Simulation results validate that the shifting control algorithm proposed in this paper can not only meet the shifting quality requirements, but also adapt to the various shifting intentions, having a strong robustness.

  7. Design optimization of clutch housing mold by fluid flow and solidification simulation

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, Seyedeh Maryam; Utlu, Zafer [Istanbul Aydin Univ., Istanbul (Turkmenistan)

    2016-06-15

    Aluminum die casting is so complex where flow momentum is critical matter in the mould filling process due the high velocity of the liquid metal. Actually, in complex parts the exact calculation of mould filling performance with using experimental knowledge is almost impossible. Aluminum die castings play a definitive role in the manufacturing of lightweight automobile bodies. Hence it is more essential today that these castings be produced with the high quality methods. In this condition the simulation is becoming more important in the designing procedure. This saves time and reduces the cost of the casting system design, which is an advantage of using simulation programs. Also, economical utilization of materials can be obtained when the quantity of test castings is decreased. This paper describes the advantages of the clutch housing die casting mold simulations to achieve better casting system design in High pressure die castings (HPDC). Filling analysis is used to determine the size and location of the gate as well as proper runner system design for ensuring a complete and balanced filling of the clutch housing part.

  8. Study on Oil Pressure Characteristics and Trajectory Tracking Control in Shift Process of Wet-Clutch for Electric Vehicles

    Directory of Open Access Journals (Sweden)

    Junqiu Li

    2016-01-01

    Full Text Available Accurate control of oil pressure of wet-clutch is of great importance for improving shift quality. Based on dynamic models of two-gear planetary transmission and hydraulic control system, a trajectory tracking model of oil pressure was built by sliding mode control method. An experiment was designed to verify the validity of hydraulic control system, through which the relationship between duty cycle of on-off valve and oil pressure of clutch was determined. The tracking effect was analyzed by simulation. Results showed that oil pressure could follow well the optimal trajectory and the shift quality was effectively improved.

  9. Metabolic rate of nocturnal incubation in female great tits, Parus major, in relation to clutch size measured in a natural environment

    NARCIS (Netherlands)

    de Heij, Maaike E.; van der Graaf, Alexandra J.; Hafner, Dennis; Tinbergen, Joost M.

    2007-01-01

    To study the energetic costs of incubation in relation to clutch size, clutch sizes were manipulated and the metabolic rate of female great tits, Parus major (Linnaeus), during nocturnal incubation (MRinc) was measured using mobile oxygen analysers. Individuals were measured on consecutive nights

  10. Density dependence of avian clutch size in resident and migrant species: is there a constraint on the predictability of competitor density?

    NARCIS (Netherlands)

    Both, C.

    2000-01-01

    The presence of density dependence of clutch size is tested in 57 long-term population studies of 10 passerine bird species. In about half of the studies of tit species Parus spp. density dependence of clutch size was found, while none was found in studies of two flycatcher species Ficedula spp. One

  11. A study of airborne chrysotile concentrations associated with handling, unpacking, and repacking boxes of automobile clutch discs.

    Science.gov (United States)

    Jiang, George C T; Madl, Amy K; Ingmundson, Kelsey J; Murbach, Dana M; Fehling, Kurt A; Paustenbach, Dennis J; Finley, Brent L

    2008-06-01

    Although automotive friction products (brakes and manual clutches) historically contained chrysotile asbestos, industrial hygiene surveys and epidemiologic studies of auto mechanics have consistently shown that these workers are not at an increased risk of developing asbestos-related diseases. Airborne asbestos levels during brake repair and brake parts handling have been well-characterized, but the potential exposure to airborne asbestos fibers during the handling of clutch parts has not been examined. In this study, breathing zone samples on the lapel of a volunteer worker (n=100) and area samples at bystander (n=50), remote area (n=25), and ambient (n=9) locations collected during the stacking, unpacking, and repacking of boxes of asbestos-containing clutches, and the subsequent cleanup and clothes handling, were analyzed by phase contrast microscopy (PCM) and transmission electron microscopy (TEM). In addition, fiber morphology and size distribution was evaluated using X-ray diffraction, polarized light microscopy, and ISO analytical methods. It was observed that the (1) airborne asbestos concentrations increased with the number of boxes unpacked and repacked, (2) repetitive stacking of unopened boxes of clutches resulted in higher asbestos concentrations than unpacking and repacking the boxes of clutches, (3) cleanup and clothes handling tasks yielded very low asbestos concentrations. Fiber size and morphology analyses showed that amphibole fibers were not detected in the clutches and that the vast majority (>95%) of the airborne chrysotile fibers were less than 20 microm in length. Applying the ratio of asbestos fibers:total fibers (including non-asbestos) as determined by TEM to the PCM results, it was found that 30-min average airborne chrysotile concentrations (PCM adjusted) were 0.026+/-0.004 f/cc or 0.100+/-0.017 f/cc for a worker unpacking and repacking 1 or 2 boxes of clutches, respectively. The 30-min PCM adjusted average airborne asbestos

  12. Optimal control of mode transition for four-wheel-drive hybrid electric vehicle with dry dual-clutch transmission

    Science.gov (United States)

    Zhao, Zhiguo; Lei, Dan; Chen, Jiayi; Li, Hangyu

    2018-05-01

    When the four-wheel-drive hybrid electric vehicle (HEV) equipped with a dry dual clutch transmission (DCT) is in the mode transition process from pure electrical rear wheel drive to front wheel drive with engine or hybrid drive, the problem of vehicle longitudinal jerk is prominent. A mode transition robust control algorithm which resists external disturbance and model parameter fluctuation has been developed, by taking full advantage of fast and accurate torque (or speed) response of three electrical power sources and getting the clutch of DCT fully involved in the mode transition process. Firstly, models of key components of driveline system have been established, and the model of five-degrees-of-freedom vehicle longitudinal dynamics has been built by using a Uni-Tire model. Next, a multistage optimal control method has been produced to realize the decision of engine torque and clutch-transmitted torque. The sliding-mode control strategy for measurable disturbance has been proposed at the stage of engine speed dragged up. Meanwhile, the double tracking control architecture that integrates the model calculating feedforward control with H∞ robust feedback control has been presented at the stage of speed synchronization. Finally, the results from Matlab/Simulink software and hardware-in-the-loop test both demonstrate that the proposed control strategy for mode transition can not only coordinate the torque among different power sources and clutch while minimizing vehicle longitudinal jerk, but also provide strong robustness to model uncertainties and external disturbance.

  13. Circulating carotenoid concentrations are positively correlated with later clutch initiation in Florida Scrub-Jays (Aphelocoma coerulescens).

    Science.gov (United States)

    Heiss, Rebecca S; Cohen, Alan A; Bowman, Reed; Boughton, Raoul K; Bridge, Eli; McGraw, Kevin J; Schoech, Stephan J

    2011-02-01

    Antioxidants play key roles in preventing free radical damage to various molecules, cells, and tissues, but it is not well understood how variation in antioxidant levels may relate to the reproductive success or health of wild animals. We explored the relationship between circulating antioxidant concentrations and both body condition and timing of reproduction in male and female Florida Scrub-Jays (Aphelocoma coerulescens), a cooperatively breeding passerine bird. We examined whether levels of uric acid, vitamin E, and carotenoids (all potentially important antioxidants) were linked to body condition and timing of reproduction, two measures that are directly related to reproductive success. Antioxidant concentrations were not correlated with body condition, but they were related to timing of first clutch initiation, though not always in the predicted direction. Elevated circulating levels of carotenoids were associated with delayed clutch initiation in female breeders. Relatively higher vitamin E levels in control birds were associated with earlier clutch initiation, whereas male breeders that received long-term food supplementation had elevated levels of vitamin E and delayed reproduction. Several potential explanations for the link between elevated levels of antioxidants and delayed clutch initiation are discussed. Separate explanations for each sex include, but are not limited to, oxidative stress as a result of territory defense efforts in males, different dietary regimes due to supplementation, and mobilized plasma antioxidants in females that were coping with a stressor. © 2010 Wiley-Liss, Inc.

  14. Choking vs. clutch performance: a study of sport performance under pressure.

    Science.gov (United States)

    Otten, Mark

    2009-10-01

    Choking research in sport has suggested that an athlete's tendency to choke, versus give a better than usual (i.e., "clutch") performance depends on his or her personality, as well as on situational influences, such as a reliance on explicit (versus implicit) knowledge when pressured. The current study integrated these hypotheses and tested a structural equation model (SEM) to predict sport performance under pressure. Two hundred and one participants attempted two sets of 15 basketball free throws, and were videotaped during their second set of shots as a manipulation of pressure. Results of the model suggest that "reinvesting" attention in the task leads to greater anxiety (cognitive and somatic), which then predicts a higher level of self-focus; self-focus, then, did not lead to improved performance under pressure, whereas feelings of self-reported "perceived control" did help performance. Implications for measurement of these constructs, and their relationships with performance, are discussed.

  15. Nonlinear gearshifts control of dual-clutch transmissions during inertia phase.

    Science.gov (United States)

    Hu, Yunfeng; Tian, Lu; Gao, Bingzhao; Chen, Hong

    2014-07-01

    In this paper, a model-based nonlinear gearshift controller is designed by the backstepping method to improve the shift quality of vehicles with a dual-clutch transmission (DCT). Considering easy-implementation, the controller is rearranged into a concise structure which contains a feedforward control and a feedback control. Then, robustness of the closed-loop error system is discussed in the framework of the input to state stability (ISS) theory, where model uncertainties are considered as the additive disturbance inputs. Furthermore, due to the application of the backstepping method, the closed-loop error system is ordered as a linear system. Using the linear system theory, a guideline for selecting the controller parameters is deduced which could reduce the workload of parameters tuning. Finally, simulation results and Hardware in the Loop (HiL) simulation are presented to validate the effectiveness of the designed controller. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  16. Electronic control of a 4-speed automatic transmission with lock-up clutch

    Energy Technology Data Exchange (ETDEWEB)

    Schwab, M.

    1984-01-01

    The paper describes the electronic control of an automatic 4-speed transmission with lock-up clutch. As compared to purely hydraulically controlled transmissions, this control offers a clearly improved quality of shifting and the possibility of achieving improvements in fuel consumption thanks to a special economy program. The electronic control unit is a Bosch MOTRONIC which has been expanded to include the functions of transmission control. A special feature is the engine torque control which is implemented by way of retarding the ignition when shifting. This opens up an additional degree of freedom for optimizing a transmission in terms of shift comfort, life of the friction elements and the power which can be transmitted.

  17. A force transmission system based on a tulip-shaped electrostatic clutch for haptic display devices

    Science.gov (United States)

    Sasaki, Hikaru; Shikida, Mitsuhiro; Sato, Kazuo

    2006-12-01

    This paper describes a novel type of force transmission system for haptic display devices. The system consists of an array of end-effecter elements, a force/displacement transmitter and a single actuator producing a large force/displacement. It has tulip-shaped electrostatic clutch devices to distribute the force/displacement from the actuator among the individual end effecters. The specifications of three components were determined to stimulate touched human fingers. The components were fabricated by using micro-electromechanical systems and conventional machining technologies, and finally they were assembled by hand. The performance of the assembled transmission system was experimentally examined and it was confirmed that each projection in the arrayed end effecters could be moved individually. The actuator in a system whose total size was only 3.0 cm × 3.0 cm × 4.0 cm produced a 600 mN force and displaced individual array elements by 18 µm.

  18. On the correlation between the shape of eggs and their quantity in the clutches of Grass snake Natrix natrix (Linnaeus, 1758

    Directory of Open Access Journals (Sweden)

    Klenina Anastasia Alexandrovna

    2014-12-01

    Full Text Available Positive correlation between the quantity of eggs in clutch of the grass snake and their diameter as well as negative correlation between quantity of eggs and their length and between the diameter of eggs and their length was revealed. It was determined that the more the quantity of eggs in the clutch, the more they are rounded, that was explained by their deformation in accumulating in the oviduct.

  19. A Study of Structural Stress Technique for Fracture Prediction of an Auto-Mobile Clutch Snap-Ring

    International Nuclear Information System (INIS)

    Kim, Ju Hee; Myeong, Man Sik; Oh, Chang Sik; Kim, Yun Jae

    2016-01-01

    The endurance reliability assessment of a highly complex mechanism is generally predicted by the fatigue life based on simple stress analysis. This study discusses various fatigue life assessment techniques for an automobile clutch snap ring. Finite element analyses were conducted to determine the structural stress on the snap ring. Structural stress that is insensitive in regards to the mesh size and type definition is presented in this study. The structural stress definition is consistent with elementary structural mechanics theory and provides an effective measure of a stress state that pertains to fatigue behavior of welded joints in the form of both membrane and bending components. Numerical procedures for both solid models and shell or plate element models are presented to demonstrate the mesh-size insensitivity when extracting the structural stress parameters. Conventional finite element models can be used with the structural stress calculations as a post-processing procedure. The two major implications from this research were: (a) structural stresses pertaining to fatigue behavior can be consistently calculated in a mesh-insensitive manner regardless of the types of finite element models; and (b) by comparing with the clutch snap-ring fatigue test data, we should predict the fatigue fractures of an automobile clutch snap ring using this method

  20. Assessment of circumferential cracks in hypereutectic Al-Si clutch housings

    Directory of Open Access Journals (Sweden)

    M. Haghshenas

    2017-04-01

    Full Text Available As in situ natural composites with silicon phase acting as the reinforcing phase, Al-Si alloys are among most commonly used aluminum alloys in automotive applications (i.e. engine component. Silicon contributes to the strength of Al-Si alloys through load transfer from the Al matrix to the hard (rigid Si phase in the microstructure (load-carrying capacity. Casting parameters (i.e. solidification rate, elemental segregation, secondary dendrite spacing… as well as the size and distribution of the microstructural constituents in Al-Si alloys (i.e. morphology of Si particles, intermetallic compounds, secondary dendrite spacing contribute directly to the mechanical response and failure (or fracture behavior of the alloy within the service. In hyper-eutectic Al-Si alloys (i.e. B390.0, distribution of coarse pre-eutectic Si particle mainly contribute to stress concentration, crack initiation and propagation during the actual service condition. In the present paper, the parameters contribution to the formation of the circumferential cracks in clutch housings made of die cast hyper-eutectics B390.0 Al-Si alloys are assessed through optical microscopy and scanning electron microscopy. Casting variable, cooling rate, their effect on the cracks as well some of the possible causes are also discussed in detail.

  1. A novel design procedure for tractor clutch fingers by using optimization and response surface methods

    Energy Technology Data Exchange (ETDEWEB)

    Dogan, Oguz; Karpat, Fatih; Yuce, Celalettin; Kaya, Necmettin; Yavuz, Nurettin [Uludag University, Gorukle (Turkmenistan); Sen, Hasan [Valeo A. S., Bursa (Turkmenistan)

    2016-06-15

    This paper presents a methodology for re-designing a failed tractor transmission component subjected to cyclic loading. Unlike other vehicles, tractors cope with tough working conditions. Thus, it is necessary to re-design components by using modern optimization techniques. To extend their service life, we present a design methodology for a failed tractor clutch power take-off finger. The finger was completely re-designed using topology and shape optimization approach. Stress-life based fatigue analyses were performed. Shape optimization and response surface methodology were conducted to obtain optimum dimensions of the finger. Two design parameters were selected for the design of experiment method and 15 cases were analyzed. By using design of the experiment method, three responses were obtained: Maximum stresses, mass, and displacement depending on the selected the design parameters. After solving the optimization problem, we achieved a maximum stress and mass reduction of 14% and 6%, respectively. The stiffness was improved up to 31.6% compared to the initial design.

  2. Applying Low-Frequency Vibration for the Experimental Investigation of Clutch Hub Forming

    Directory of Open Access Journals (Sweden)

    De’an Meng

    2018-05-01

    Full Text Available A vibration-assisted plastic-forming method was proposed, and its influence on clutch hub forming process was investigated. The experiments were conducted on a vibration-assisted hydraulic extrusion press with adjustable frequency and amplitude. Vibration frequency and amplitude were considered in investigating the effect of vibration on forming load and surface quality. Results showed that applying vibration can effectively reduce forming force and improve surface quality. The drop in forming load was proportional to the vibration frequency and amplitude, and the load decreased by up to 25%. Such reduction in forming load raised with amplitude increase because the increase in amplitude would accelerate punch relative speed, which then weakened the adhesion between workpiece and dies. By increasing the vibration frequency, the punch movement was enhanced, and the number of attempts to drag the lubricant out of the pits was increased. In this manner, the lubrication condition was improved greatly. The 3D surface topography testing confirmed the assumption. Moreover, vibration frequency exerted a more significant effect on the forming load reduction than vibration amplitude.

  3. Design and analysis of the Gemini chain system in dual clutch transmission of automobile

    Science.gov (United States)

    Cheng, Yabing; Guo, Haitao; Fu, Zhenming; Wan, Nen; Li, Lei; Wang, Yang

    2015-01-01

    Chain drive system is widely used in the conditions of high-speed, overload, variable speed and load. Many studies are focused on the meshing theory and wear characteristics of chain drive system, but system design, analysis, and noise characteristics of the chain drive system are weak. System design and noise characteristic are studied for a new type Gemini chain of dual-clutch automatic transmission. Based on the meshing theory of silent chain, the design parameters of the Gemini chain system are calculated and the mathematical models and dynamic analysis models of the Gemini chain system are established. Dynamic characteristics of the Gemini chain system is simulated and the contact force of plate and pin, plate and sprockets, the chain tension forces, the transmission error and the stress of plates and pins are analyzed. According to the simulation results of the Gemini chain system, the noise experiment about system is carried out. The noise values are tested at different speed and load and spectral characteristics are analyzed. The results of simulation and experimental show that the contact forces of plate and pin, plate and sprockets are smaller than the allowable stress values, the chain tension force is less than ultimate tension and transmission error is limited in 1.2%. The noise values can meet the requirements of industrial design, and it is proved that the design and analysis method of the Gemini chain system is scientific and feasible. The design and test system is built from analysis to test of Gemini chain system. This research presented will provide a corresponding theoretical guidance for the design and dynamic characteristics and noise characteristics of chain drive system.

  4. The multivariate egg: quantifying within- and among-clutch correlations between maternally derived yolk immunoglobulins and yolk androgens using multivariate mixed models.

    Science.gov (United States)

    Postma, Erik; Siitari, Heli; Schwabl, Hubert; Richner, Heinz; Tschirren, Barbara

    2014-03-01

    Egg components are important mediators of prenatal maternal effects in birds and other oviparous species. Because different egg components can have opposite effects on offspring phenotype, selection is expected to favour their mutual adjustment, resulting in a significant covariation between egg components within and/or among clutches. Here we tested for such correlations between maternally derived yolk immunoglobulins and yolk androgens in great tit (Parus major) eggs using a multivariate mixed-model approach. We found no association between yolk immunoglobulins and yolk androgens within clutches, indicating that within clutches the two egg components are deposited independently. Across clutches, however, there was a significant negative relationship between yolk immunoglobulins and yolk androgens, suggesting that selection has co-adjusted their deposition. Furthermore, an experimental manipulation of ectoparasite load affected patterns of covariance among egg components. Yolk immunoglobulins are known to play an important role in nestling immune defence shortly after hatching, whereas yolk androgens, although having growth-enhancing effects under many environmental conditions, can be immunosuppressive. We therefore speculate that variation in the risk of parasitism may play an important role in shaping optimal egg composition and may lead to the observed pattern of yolk immunoglobulin and yolk androgen deposition across clutches. More generally, our case study exemplifies how multivariate mixed-model methodology presents a flexible tool to not only quantify, but also test patterns of (co)variation across different organisational levels and environments, allowing for powerful hypothesis testing in ecophysiology.

  5. Simulacioni model višelamelastih frikcionih sklopova / Simulation model of multiple plate friction clutches and brakes

    Directory of Open Access Journals (Sweden)

    Aleksandar Grkić

    2009-01-01

    Full Text Available Višelamelasti frikcioni sklopovi koriste se za promenu stepena prenosa u planetarnim menjačkim prenosnicima motornih vozila. Razvijeni simulacioni model frikcione spojnice i kočnice omogućava simulaciju rada menjačkog prenosnika pri promeni stepena prenosa. Primenom razvijenog modela moguće je na bazi simulacije analizirati prelazni proces pri promeni stepena prenosa i obezbediti identifikaciju relevantnih parametara bez izrade većeg broja fizičkih prototipova. Na taj način obezbeđuje se smanjenje troškova i skraćenje procesa razvoja novih prenosnika snage, uz poboljšanje upotrebnog kvaliteta. Simulacioni model može da se koristi i pri razvoju upravljačkog sistema menjačkog prenosnika za definisanje potrebnih karakteristika njegovih komponenata. / Multiple plate friction clutches and brakes are used for gear shifting within planetary gear trains of motor vehicles. The developed simulation model of the friction clutch and brake enables the simulation and the analysis of the planetary gear train transitional processes during gear shifting and provides identification of relevant parameters without making numerous physical prototypes. Costs are thus reduced and time for developing new gear trains shortened, while the product quality is increased. The simulation model can be use additionally in developing steering systems of planetary gear trains for defining characteristics of their components.

  6. Clutch and egg allometry of the turtle Mauremys leprosa (Chelonia: Geoemydidae) from a polluted peri-urban river in west-central Morocco

    Science.gov (United States)

    Naimi, Mohamed; Znari, Mohammed; Lovich, Jeffrey E.; Feddadi, Youssef; Baamrane, Moulay Abdeljalil Ait

    2012-01-01

    We examined the relationships of clutch size (CS) and egg size to female body size (straight-line carapace length, CL) in a population of the turtle Mauremys leprosa from a polluted segment of oued (river) Tensift in arid west-central Morocco. Twenty-eight adult females were collected in May–July, 2009 and all were gravid. Each was weighed, measured, humanely euthanized and then dissected. Oviductal shelled eggs were removed, weighed (egg mass, EM) and measured for length (EL) and width (EW). Clutch mass (CM) was the sum of EM for a clutch. Pelvic aperture width (PAW) was measured at the widest point between the ilia bones through which eggs must pass at oviposition. The smallest gravid female had a CL of 124.0 mm. Mean CS was relatively large (9.7±2.0 eggs, range: 3–13) and may reflect high productivity associated with polluted (eutrophic) waters. Regression analyses were conducted using log-transformed data. CM increased isometrically with maternal body size. CS, EW and EM were all significantly hypoallometric in their relationship with CL. EL did not change significantly with increases in CL. EW increased at a hypoallometric rate with increasing CL but was unconstrained by PAW since the widest egg was smaller than the narrowest PAW measurement when excluding the three smallest females. Smaller females may have EW constrained by PAW. As females increase in size they increase both clutch size and egg width in contradiction to predictions of optimal egg size theory.

  7. Within-Clutch Variation in Yolk Testosterone as an Adaptive Maternal Effect to Modulate Avian Sibling Competition : Evidence from a Comparative Study

    NARCIS (Netherlands)

    Muller, Martina; Groothuis, Ton G. G.; Bronstein, Judith L.; Demas, Greg

    In many species, embryos are exposed to maternal hormones in utero, in the egg, or in the seed. In birds, mothers deposit substantial testosterone into their eggs, which enhances competitive ability of offspring. These maternal testosterone concentrations vary systematically within clutches in

  8. Clutch size variation in Tawny Owls (Strix aluco) from adjacent valley systems: can this be used as a surrogate to investigate temporal and spatial variations in vole density?

    Science.gov (United States)

    Steve J. Petty; Billy L. Fawkes

    1997-01-01

    Research on Tawny Owls (Strix aluco) in Kielder Forest, northern England, since 1981 demonstrated that field voles (Microtus agrestis) were their most important food. Here, field voles exhibited a 3-4 year cycle of abundance, and mean clutch size in Tawny Owls was significantly related to vole abundance in March. In this analysis...

  9. Evaluation of asbestos exposure within the automotive repair industry: a study involving removal of asbestos-containing body sealants and drive clutch replacement.

    Science.gov (United States)

    Blake, Charles L; Dotson, G Scott; Harbison, Raymond D

    2008-12-01

    Two independent assessments were performed of airborne asbestos concentrations generated during automotive repair work on vintage vehicles . The first involved removal of asbestos-containing seam sealant, and the second involved servicing of a drive clutch. Despite the relatively high concentrations (5.6-28%) of chrysotile fibers detected within bulk samples of seam sealant, the average asbestos concentration for personal breathing zone (PBZ) samples during seam sealant removal was 0.006 f/cc (fibers/cubic centimeter of air). Many other air samples contained asbestos at or below the analytical limit of detection (LOD). Pneumatic chiseling of the sealant material during removal resulted in 69% of area air samples containing asbestos. Use of this impact tool liberated more asbestos than hand scraping. Asbestos fibers were only detected in air samples collected during the installation of a replacement clutch. The highest asbestos corrected airborne fiber concentration observed during clutch installation was 0.0028 f/cc. This value is approximately 100 times lower than Occupational Safety and Health Administration's (OSHA) permissible exposure limit (PEL) of 0.1f/cc. The airborne asbestos concentrations observed during the servicing of vintage vehicles with asbestos-containing seam sealant and clutches are comparable to levels reported for repair work involving brake components and gaskets.

  10. Research on Gear Shifting Process without Disengaging Clutch for a Parallel Hybrid Electric Vehicle Equipped with AMT

    Directory of Open Access Journals (Sweden)

    Hui-Long Yu

    2014-01-01

    Full Text Available Dynamic models of a single-shaft parallel hybrid electric vehicle (HEV equipped with automated mechanical transmission (AMT were described in different working stages during a gear shifting process without disengaging clutch. Parameters affecting the gear shifting time, components life, and gear shifting jerk in different transient states during a gear shifting process were deeply analyzed. The mathematical models considering the detailed synchronizer working process which can explain the gear shifting failure, long time gear shifting, and frequent synchronizer failure phenomenon in HEV were derived. Dynamic coordinated control strategy of the engine, motor, and actuators in different transient states considering the detailed working stages of synchronizer in a gear shifting process of a HEV is for the first time innovatively proposed according to the state of art references. Bench test and real road test results show that the proposed control strategy can improve the gear shifting quality in all its evaluation indexes significantly.

  11. Two-stage actuation system using DC motors and piezoelectric actuators for controllable industrial and automotive brakes and clutches

    Science.gov (United States)

    Neelakantan, Vijay A.; Washington, Gregory N.; Bucknor, Norman K.

    2005-05-01

    High bandwidth actuation systems that are capable of simultaneously producing relatively large forces and displacements are required for use in automobiles and other industrial applications. Conventional hydraulic actuation mechanisms used in automotive brakes and clutches are complex, inefficient and have poor control robustness. These lead to reduced fuel economy, controllability issues and other disadvantages. This paper involves the design, development, testing and control of a two-stage hybrid actuation mechanism by combining classical actuators like DC motors and advanced smart material actuators like piezoelectric actuators. The paper also discusses the development of a robust control methodology using the Internal Model Control (IMC) principle and emphasizes the robustness property of this control methodology by comparing and studying simulation and experimental results.

  12. Dynamic Coordinated Shifting Control of Automated Mechanical Transmissions without a Clutch in a Plug-In Hybrid Electric Vehicle

    Directory of Open Access Journals (Sweden)

    Xinlei Liu

    2012-08-01

    Full Text Available On the basis of the shifting process of automated mechanical transmissions (AMTs for traditional hybrid electric vehicles (HEVs, and by combining the features of electric machines with fast response speed, the dynamic model of the hybrid electric AMT vehicle powertrain is built up, the dynamic characteristics of each phase of shifting process are analyzed, and a control strategy in which torque and speed of the engine and electric machine are coordinatively controlled to achieve AMT shifting control for a plug-in hybrid electric vehicle (PHEV without clutch is proposed. In the shifting process, the engine and electric machine are well controlled, and the shift jerk and power interruption and restoration time are reduced. Simulation and real car test results show that the proposed control strategy can more efficiently improve the shift quality for PHEVs equipped with AMTs.

  13. Record length, mass, and clutch size in the nonindigenous Burmese Python, Python bivittatus Kuhl 1820 (Squamata: Pythonidae), in Florida

    Science.gov (United States)

    Krysko, Kenneth L.; Hart, Kristen M.; Smith, Brian J.; Selby, Thomas H.; Cherkiss, Michael S.; Coutu, Nicholas T.; Reichart, Rebecca M.; Nuñez, Leroy P.; Mazzotti, Frank J.; Snow, Ray W.

    2012-01-01

    The Burmese Python, Python bivittatus Kuhl 1820 (Squamata: Pythonidae), is indigenous to northern India,east to southern China, and south to Vietnam and a few islands in Indonesia (Barker and Barker 2008, Reed and Rodda 2009). This species has been introduced since at least 1979 in southern Florida, USA, where it likely began reproducing and became established during the 1980s (Meshaka et al. 2000, Snowet al. 2007b,Kraus 2009, Krysko et al. 2011, Willson et al. 2011). Python bivittatus has been documented in Florida consuming a variety of mammals and birds, and the American Alligator(Alligator mississippiensis) (Snowet al. 2007a, 2007b; Harvey et al. 2008; Rochford et al. 2010b; Holbrook and Chesnes 2011), many of which are protected species. Herein, we provide details on two of the largest known wild P. bivittatus in Florida to date, including current records on length,mass,clutch size, and diet.

  14. Experimental Investigation on The Electromagnetic Clutch Water pump and Pneumatic Compressor for Improving the Efficiency of an Engine

    Science.gov (United States)

    Kumarasubramanian, R.; Xavier, Goldwin; Nishanthi, W. Mary; Rajasekar, R.

    2017-05-01

    Considering the fuel crises today many work and research were conducted to reduce the fuel consumption of the internal combustion engine. The fuel consumption of an internal combustion engine can be relatively reduced by use of the electromagnetic clutch water pump and pneumatic compressor. Normally in an engine, the water pump is driven by the crankshaft, with an aid of belt, for the circulation of the water for the cooling process. The circulation of coolant is resisted by the thermostat valve, while the temperature inside the coolant jacket of the engine is below 375K the thermostat is closed only above 375K it tends to open. But water pump run continuously even when thermostat is closed. In pneumatic braking system, pneumatic or air compressor purpose is to compress the air and stored into the storage tank for the brake operation. When the air pressure of the storage tanks gets increases above its storage capacity pressure is regulated by governor, by passing them to atmosphere. Such unnecessary work of this water pump and air compressor can be minimized by use of the electromagnetic clutch water pump and air compressor. The European Driving Cycle is used to evaluate the performance of this water pump and air compressor when used in an engine. The result shows that the fuel economy of the engine while using electromagnetic water pump and pneumatic compressor were improved by 8.0% compared with conventional types which already exist. The application of these electromagnetic water pump and pneumatic compressor are expected to contribute for the improvement of engine performance because of their effect in reduction of the rate of fuel consumption.

  15. Estimation of genetic variability and selection response for clutch length in dwarf brown-egg layers carrying or not the naked neck gene

    Directory of Open Access Journals (Sweden)

    Tixier-Boichard Michèle

    2003-03-01

    Full Text Available Abstract In order to investigate the possibility of using the dwarf gene for egg production, two dwarf brown-egg laying lines were selected for 16 generations on average clutch length; one line (L1 was normally feathered and the other (L2 was homozygous for the naked neck gene NA. A control line from the same base population, dwarf and segregating for the NA gene, was maintained during the selection experiment under random mating. The average clutch length was normalized using a Box-Cox transformation. Genetic variability and selection response were estimated either with the mixed model methodology, or with the classical methods for calculating genetic gain, as the deviation from the control line, and the realized heritability, as the ratio of the selection response on cumulative selection differentials. Heritability of average clutch length was estimated to be 0.42 ± 0.02, with a multiple trait animal model, whereas the estimates of the realized heritability were lower, being 0.28 and 0.22 in lines L1 and L2, respectively. REML estimates of heritability were found to decline with generations of selection, suggesting a departure from the infinitesimal model, either because a limited number of genes was involved, or their frequencies were changed. The yearly genetic gains in average clutch length, after normalization, were estimated to be 0.37 ± 0.02 and 0.33 ± 0.04 with the classical methods, 0.46 ± 0.02 and 0.43 ± 0.01 with animal model methodology, for lines L1 and L2 respectively, which represented about 30% of the genetic standard deviation on the transformed scale. Selection response appeared to be faster in line L2, homozygous for the NA gene, but the final cumulated selection response for clutch length was not different between the L1 and L2 lines at generation 16.

  16. Analysis and Design of a Permanent Magnet Bi-Stable Electro-Magnetic Clutch Unit for In-Wheel Electric Vehicle Drives

    Directory of Open Access Journals (Sweden)

    Wanli Cai

    2015-06-01

    Full Text Available Clutches have been used in internal combustion vehicles and concentrated electric vehicles (EVs to smoothen impulsion while starting and shifting. This paper proposes a permanent magnet bi-stable electromagnetic clutch unit (PMBECU which is specially introduced into in-wheel EVs to make the rigid connection between hub and wheel more flexible. Firstly, the operation principle of the PMBECU is illustrated. Then, the basic magnetic circuit model is presented and analyzed, followed by optimal design of the main structural parameters by investigating the PM leakage flux coefficient. Further, according to the basic electromagnetic characteristics of the PMBECU, the current pulse supply is put forward, and the minimum pulse width which enables the operation of the PMBECU and its dynamic characteristics are analyzed by an improved finite element method. Finally, a prototype machine is manufactured and tested to validate all the analysis results.

  17. Carry-over effects of winter location contribute to variation in timing of nest initiation and clutch size in black brant (Branta bernicla nigricans)

    Science.gov (United States)

    Schamber, Jason L.; Sedinger, James S.; Ward, David H.

    2012-01-01

    We assessed carry-over effects from winter location on timing of nest initiation and clutch size of Black Brant (Branta bernicla nigricans) using observations of individually marked brant breeding at the Tutakoke River colony in Alaska, and wintering along a latitudinal gradient at three areas on the Pacific coast of Baja California: northernmost Bahia San Quintin (BSQ), Laguna Ojo de Liebre (LOL), and southernmost Laguna San Ignacio (LSI). Black Brant initiated nests according to a north—south trend in winter location, although year was a stronger predictor of initiation date than was wintering site. Female Black Brant that wintered at BSQ initiated nests 2.2 days earlier than females from LSI. Conversely, Black Brant showed only a weak south—north trend in clutch size; individuals from LSI laid slightly larger clutches than individuals from BSQ, probably because a smaller proportion of only high-quality females from the southernmost wintering area in Baja California were able to attain the nutritional condition necessary to breed. These results indicate that winter location can influence individual reproductive performance and, potentially, limit population growth of southern segments of the wintering Black Brant population.

  18. Effects of sea ice on breeding numbers and clutch size of a high arctic population of the common eider Somateria mollissima

    Science.gov (United States)

    Mehlum, Fridtjof

    2012-04-01

    The breeding performance of high-arctic bird populations shows large inter-annual variation that may be attributed to environmental variability, such as the timing of snow melt and break-up of the landfast sea ice that surrounds breeding colonies on islands and along coasts. In the Kongsfjorden area (79°N) on Svalbard, the number of breeding pairs and the average egg clutch size vary considerably among years. In this study, data on breeding performance are presented from 15 years in the period 1981-2000. The results showed that early break-up of sea ice in Kongsfjorden resulted in larger numbers of nests and larger average clutch sizes than late break-up. Also, individual islands with early break-up of sea ice in a particular year had more nests and larger clutch sizes compared to other islands surrounded by sea ice during a longer period in spring. Thus, the inter-annual variation in the break-up of sea ice in the fjord has considerable implications for the inter-annual variability of recruitment to the population. The results indicate that the effects of global warming on changes in the sea ice melting regime in coastal regions are important for the reproductive output of island-nesting eiders.

  19. Genomic dissection of variation in clutch size and egg mass in a wild great tit (Parus major) population.

    Science.gov (United States)

    Santure, Anna W; De Cauwer, Isabelle; Robinson, Matthew R; Poissant, Jocelyn; Sheldon, Ben C; Slate, Jon

    2013-08-01

    Clutch size and egg mass are life history traits that have been extensively studied in wild bird populations, as life history theory predicts a negative trade-off between them, either at the phenotypic or at the genetic level. Here, we analyse the genomic architecture of these heritable traits in a wild great tit (Parus major) population, using three marker-based approaches - chromosome partitioning, quantitative trait locus (QTL) mapping and a genome-wide association study (GWAS). The variance explained by each great tit chromosome scales with predicted chromosome size, no location in the genome contains genome-wide significant QTL, and no individual SNPs are associated with a large proportion of phenotypic variation, all of which may suggest that variation in both traits is due to many loci of small effect, located across the genome. There is no evidence that any regions of the genome contribute significantly to both traits, which combined with a small, nonsignificant negative genetic covariance between the traits, suggests the absence of genetic constraints on the independent evolution of these traits. Our findings support the hypothesis that variation in life history traits in natural populations is likely to be determined by many loci of small effect spread throughout the genome, which are subject to continued input of variation by mutation and migration, although we cannot exclude the possibility of an additional input of major effect genes influencing either trait. © 2013 John Wiley & Sons Ltd.

  20. Model for adhesion clutch explains biphasic relationship between actin flow and traction at the cell leading edge

    Science.gov (United States)

    Craig, Erin M.; Stricker, Jonathan; Gardel, Margaret L.; Mogilner, Alex

    2015-01-01

    Cell motility relies on the continuous reorganization of a dynamic actin-myosin-adhesion network at the leading edge of the cell, in order to generate protrusion at the leading edge and traction between the cell and its external environment. We analyze experimentally measured spatial distributions of actin flow, traction force, myosin density, and adhesion density in control and pharmacologically perturbed epithelial cells in order to develop a mechanical model of the actin-adhesion-myosin self-organization at the leading edge. A model in which the F-actin network is treated as a viscous gel, and adhesion clutch engagement is strengthened by myosin but weakened by actin flow, can explain the measured molecular distributions and correctly predict the spatial distributions of the actin flow and traction stress. We test the model by comparing its predictions with measurements of the actin flow and traction stress in cells with fast and slow actin polymerization rates. The model predicts how the location of the lamellipodium-lamellum boundary depends on the actin viscosity and adhesion strength. The model further predicts that the location of the lamellipodium-lamellum boundary is not very sensitive to the level of myosin contraction. PMID:25969948

  1. Africa Insight

    African Journals Online (AJOL)

    Africa Insight is a quarterly, peer-reviewed journal of the Africa Institute of South Africa. It is accredited by the South African National Department of Higher Education and Training (DHET) and is indexed in the International Bibliography of Social Science (IBSS). It is a multi-disciplinary journal primarily focusing on African ...

  2. Interspecific variation in the relationship between clutch size, laying date and intensity of urbanization in four species of hole-nesting birds.

    Science.gov (United States)

    Vaugoyeau, Marie; Adriaensen, Frank; Artemyev, Alexandr; Bańbura, Jerzy; Barba, Emilio; Biard, Clotilde; Blondel, Jacques; Bouslama, Zihad; Bouvier, Jean-Charles; Camprodon, Jordi; Cecere, Francesco; Charmantier, Anne; Charter, Motti; Cichoń, Mariusz; Cusimano, Camillo; Czeszczewik, Dorota; Demeyrier, Virginie; Doligez, Blandine; Doutrelant, Claire; Dubiec, Anna; Eens, Marcel; Eeva, Tapio; Faivre, Bruno; Ferns, Peter N; Forsman, Jukka T; García-Del-Rey, Eduardo; Goldshtein, Aya; Goodenough, Anne E; Gosler, Andrew G; Grégoire, Arnaud; Gustafsson, Lars; Harnist, Iga; Hartley, Ian R; Heeb, Philipp; Hinsley, Shelley A; Isenmann, Paul; Jacob, Staffan; Juškaitis, Rimvydas; Korpimäki, Erkki; Krams, Indrikis; Laaksonen, Toni; Lambrechts, Marcel M; Leclercq, Bernard; Lehikoinen, Esa; Loukola, Olli; Lundberg, Arne; Mainwaring, Mark C; Mänd, Raivo; Massa, Bruno; Mazgajski, Tomasz D; Merino, Santiago; Mitrus, Cezary; Mönkkönen, Mikko; Morin, Xavier; Nager, Ruedi G; Nilsson, Jan-Åke; Nilsson, Sven G; Norte, Ana C; Orell, Markku; Perret, Philippe; Perrins, Christopher M; Pimentel, Carla S; Pinxten, Rianne; Richner, Heinz; Robles, Hugo; Rytkönen, Seppo; Senar, Juan Carlos; Seppänen, Janne T; Pascoal da Silva, Luis; Slagsvold, Tore; Solonen, Tapio; Sorace, Alberto; Stenning, Martyn J; Tryjanowski, Piotr; von Numers, Mikael; Walankiewicz, Wieslaw; Møller, Anders Pape

    2016-08-01

    The increase in size of human populations in urban and agricultural areas has resulted in considerable habitat conversion globally. Such anthropogenic areas have specific environmental characteristics, which influence the physiology, life history, and population dynamics of plants and animals. For example, the date of bud burst is advanced in urban compared to nearby natural areas. In some birds, breeding success is determined by synchrony between timing of breeding and peak food abundance. Pertinently, caterpillars are an important food source for the nestlings of many bird species, and their abundance is influenced by environmental factors such as temperature and date of bud burst. Higher temperatures and advanced date of bud burst in urban areas could advance peak caterpillar abundance and thus affect breeding phenology of birds. In order to test whether laying date advance and clutch sizes decrease with the intensity of urbanization, we analyzed the timing of breeding and clutch size in relation to intensity of urbanization as a measure of human impact in 199 nest box plots across Europe, North Africa, and the Middle East (i.e., the Western Palearctic) for four species of hole-nesters: blue tits (Cyanistes caeruleus), great tits (Parus major), collared flycatchers (Ficedula albicollis), and pied flycatchers (Ficedula hypoleuca). Meanwhile, we estimated the intensity of urbanization as the density of buildings surrounding study plots measured on orthophotographs. For the four study species, the intensity of urbanization was not correlated with laying date. Clutch size in blue and great tits does not seem affected by the intensity of urbanization, while in collared and pied flycatchers it decreased with increasing intensity of urbanization. This is the first large-scale study showing a species-specific major correlation between intensity of urbanization and the ecology of breeding. The underlying mechanisms for the relationships between life history and

  3. Dynamics and stability of rigid rotors levitated by passive cylinder-magnet bearings and driven/supported axially by pointwise contact clutch

    DEFF Research Database (Denmark)

    Andersen, Søren Bøgh; Enemark, Søren; Santos, Ilmar

    2013-01-01

    A stable rotor—supported laterally by passive magnetic bearings and longitudinally by magnetic forces and a clutch—loses suddenly its contact to the clutch and executes abruptly longitudinal movements away from its original equilibrium position as a result of small increases in angular velocity...... by MCMB using several configurations of magnet distribution are described based on an accurate nonlinear model able to reliably reproduce the rotor-bearing dynamic behaviour. Such investigations lead to: (a) clear physical explanation about the reasons for the rotor's unstable behaviour, losing its...

  4. The Role of Counter-Face Roughness on the Tribological Performance of a Clutch System Tested with a Pin-On-Disc Tribometer

    Directory of Open Access Journals (Sweden)

    Graciliano Fernandes

    2016-05-01

    Full Text Available This study was a continuous investigation of the roles played by the tribofilm on dry automotive clutch system performance. Tribological experiments were performed by the addition of wear debris at the beginning of tribometer tests and by reducing the surface roughness of a cast iron counter-face. The initial surface conditions of cast discs were 0.2 and 1.2 µm. The pin-on-disc tests were carried out at three different PV levels: 3.08, 7.88, and 10.09 MPa·ms−1, and the current results were correlated to those previously obtained in the standard tribometer procedure. When the wear debris was added into the tribosystem, the friction coefficient level dropped drastically while the assembly wear rate rose. In contrast, the modified cast discs provided a reduced wear rate of assembly and a higher and more stable friction coefficient level. These improvements were obtained in a severe condition where higher temperature levels were reached. For the tests with added debris, SEM observations revealed a more intense tribofilm development over the worn surfaces of the clutch friction material. The smoothest cast disc did not damage the developed tribofilms and maintained them more stably due to a reduction in contact area stresses at the highest tribometer test.

  5. Experimentally reducing clutch size reveals a fixed upper limit to egg size in snakes, evidence from the king ratsnake, Elaphe carinata.

    Science.gov (United States)

    Ji, Xiang; Du, Wei-Guo; Li, Hong; Lin, Long-Hui

    2006-08-01

    Snakes are free of the pelvic girdle's constraint on maximum offspring size, and therefore present an opportunity to investigate the upper limit to offspring size without the limit imposed by the pelvic girdle dimension. We used the king ratsnake (Elaphe carinata) as a model animal to examine whether follicle ablation may result in enlargement of egg size in snakes and, if so, whether there is a fixed upper limit to egg size. Females with small sized yolking follicles were assigned to three manipulated, one sham-manipulated and one control treatments in mid-May, and two, four or six yolking follicles in the manipulated females were then ablated. Females undergoing follicle ablation produced fewer, but larger as well as more elongated, eggs than control females primarily by increasing egg length. This finding suggests that follicle ablation may result in enlargement of egg size in E. carinata. Mean values for egg width remained almost unchanged across the five treatments, suggesting that egg width is more likely to be shaped by the morphological feature of the oviduct. Clutch mass dropped dramatically in four- and six-follicle ablated females. The function describing the relationship between size and number of eggs reveals that egg size increases with decreasing clutch size at an ever-decreasing rate, with the tangent slope of the function for the six-follicle ablation treatment being -0.04. According to the function describing instantaneous variation in tangent slope, the maximum value of tangent slope should converge towards zero. This result provides evidence that there is a fixed upper limit to egg size in E. carinata.

  6. Genetic algorithm based on optimization of neural network structure for fault diagnosis of the clutch retainer mechanism of MF 285 tractor

    Directory of Open Access Journals (Sweden)

    S. F Mousavi

    2016-09-01

    Full Text Available Introduction The diagnosis of agricultural machinery faults must be performed at an opportune time, in order to fulfill the agricultural operations in a timely manner and to optimize the accuracy and the integrity of a system, proper monitoring and fault diagnosis of the rotating parts is required. With development of fault diagnosis methods of rotating equipment, especially bearing failure, the security, performance and availability of machines has been increasing. In general, fault detection is conducted through a specific procedure which starts with data acquisition and continues with features extraction, and subsequently failure of the machine would be detected. Several practical methods have been introduced for fault detection in rotating parts of machineries. The review of the literature shows that both Artificial Neural Networks (ANN and Support Vector Machines (SVM have been used for this purpose. However, the results show that SVM is more effective than Artificial Neural Networks in fault detection of such machineries. In some smart detection systems, incorporating an optimized method such as Genetic Algorithm in the Neural Network model, could improve the fault detection procedure. Consequently, the fault detection performance of neural networks may also be improved by combining with the Genetic Algorithm and hence will be comparable with the performance of the Support Vector Machine. In this study, the so called Genetic Algorithm (GA method was used to optimize the structure of the Artificial Neural Networks (ANN for fault detection of the clutch retainer mechanism of Massey Ferguson 285 tractor. Materials and Methods The test rig consists of some electro mechanical parts including the clutch retainer mechanism of Massey Ferguson 285 tractor, a supporting shaft, a single-phase electric motor, a loading mechanism to model the load of the tractor clutch and the corresponding power train gears. The data acquisition section consists of a

  7. Development of free running differential. Development of differential with an actuator and a clutch which disconnects the traction; Free running defu no kaihatsu. Kirippanashi kiko oyobi actuator wo naizoshita differential sochi no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Yamazaki, N; Teraoka, M; Ishikawa, O; Nagaoka, T; Ugajin, K [Tochigi Fuji Sangyo Co. Ltd., Tochigi (Japan)

    1997-10-01

    Free Running Differential has an effect on fuel economy and noise reduction from drive line for four wheel drive vehicle. It has an actuator and a clutch which disconnects the traction from no driving side tire when two wheel drive is selected. this unit can be installed in conventional differential carrier with no design change. It is compact in design and low in cost. We evaluate it as having a dominant position among any other Free running system. 7 figs.

  8. Within-clutch variation in yolk testosterone as an adaptive maternal effect to modulate avian sibling competition: evidence from a comparative study.

    Science.gov (United States)

    Muller, Martina; Groothuis, Ton G G

    2013-01-01

    In many species, embryos are exposed to maternal hormones in utero, in the egg, or in the seed. In birds, mothers deposit substantial testosterone into their eggs, which enhances competitive ability of offspring. These maternal testosterone concentrations vary systematically within clutches in different patterns and may enable mothers to adaptively fine-tune competitive hierarchies within broods. We performed a comparative analysis to investigate this hypothesis using a broad set of avian species. We expected species with small size differences among siblings (arising from small hatching asynchrony or slow growth rates) to aim for survival of the whole brood in good years and therefore compensate last-hatching eggs with relatively more testosterone. We expected species with large size differences among siblings (large hatching asynchrony or fast growth rates) to produce surplus young as insurance against failed offspring and to facilitate elimination of redundant surplus young by bestowing last-hatching eggs with relatively less testosterone. As predicted, we found that maternal testosterone compensation to last-hatching eggs is stronger when size differences among siblings become smaller. Maternal testosterone compensation to last-hatching eggs also correlated negatively with hatching asynchrony and growth rates. These findings provide evidence for correlated evolution of several maternal effects that together support different maternal reproductive strategies.

  9. Variation in levels of reactive oxygen species is explained by maternal identity, sex and body-size-corrected clutch size in a lizard

    Science.gov (United States)

    Olsson, Mats; Wilson, Mark; Uller, Tobias; Mott, Beth; Isaksson, Caroline

    2009-01-01

    Many organisms show differences between males and females in growth rate and crucial life history parameters, such as longevity. Considering this, we may expect levels of toxic metabolic by-products of the respiratory chain, such as reactive oxygen species (ROS), to vary with age and sex. Here, we analyse ROS levels in female Australian painted dragon lizards ( Ctenophorus pictus) and their offspring using fluorescent probes and flow cytometry. Basal level of four ROS species (singlet oxygen, peroxynitrite, superoxide and H2O2) measured with a combined marker, and superoxide measured specifically, varied significantly among families but not between the sexes. When blood cells from offspring were chemically encouraged to accelerate the electron transport chain by mitochondrial uncoupling, net superoxide levels were three times higher in daughters than sons (resulting in levels outside of the normal ROS range) and varied among mothers depending on offspring sex (significant interaction between maternal identity and offspring sex). In offspring, there were depressive effects on ROS of size-controlled relative clutch size, which relies directly on circulating levels of vitellogenin, a confirmed antioxidant in some species. Thus, levels of reactive oxygen species varies among females, offspring and in relation to reproductive investment in a manner that makes its regulatory processes likely targets of selection.

  10. What ecological factors can affect albumen corticosterone levels in the clutches of seabirds? Timing of breeding, disturbance and laying order in rockhopper penguins (Eudyptes chrysocome chrysocome).

    Science.gov (United States)

    Poisbleau, M; Demongin, L; Angelier, F; Dano, S; Lacroix, A; Quillfeldt, P

    2009-06-01

    Female birds deposit corticosterone into their eggs. Elevated concentrations of this hormone may interfere with the development of their offspring, and mothers should thus regulate corticosterone levels deposited into the eggs adaptively. However, if females are unable to regulate deposition, then the corticosterone concentration in eggs should reflect that in female plasma and should be influenced by stressors to the females. We measured corticosterone levels in the albumen of rockhopper penguins, and assessed their relationship with hatching order, human disturbance and laying date. Rockhopper penguins (Eudyptes chrysocome chrysocome) lay two eggs, of which the second egg (B-egg) is larger and hatches faster than the first egg (A-egg). The chick hatching from the B-egg is also much more likely to survive than its sibling. Albumen corticosterone concentrations were lower in B-eggs. However, as B-eggs contained more albumen than A-eggs, the total corticosterone deposited in the albumen was not significantly different between the two eggs. Daily disturbance by human observers during albumen production did not influence albumen corticosterone levels. Laying date had an effect on total albumen corticosterone through a higher albumen mass. However, we observed a high individual component in the composition of eggs from the same clutch. Thus, more work is required to explore the hypotheses of passive versus active transfer to eggs and to understand the adaptive value of contrary effects on the amount and concentration of corticosterone.

  11. Proofs that Develop Insight

    Science.gov (United States)

    Weber, Keith

    2010-01-01

    Many mathematics educators have noted that mathematicians do not only read proofs to gain conviction but also to obtain insight. The goal of this article is to discuss what this insight is from mathematicians' perspective. Based on interviews with nine research-active mathematicians, two sources of insight are discussed. The first is reading a…

  12. Intra-clutch and inter-colony variability in element concentrations in eggshells of the black-headed gull, Chroicocephalus ridibundus, in northern Poland.

    Science.gov (United States)

    Kitowski, Ignacy; Indykiewicz, Piotr; Wiącek, Dariusz; Jakubas, Dariusz

    2017-04-01

    Eggshells are good bioindicators of environmental contamination, and therefore, the concentrations of 17 trace elements in 87 eggshells of black-headed gulls, Chroicocephalus ridibundus, were determined in five breeding colonies in an area dominated by farmland in northern Poland. The intra-clutch variability in the eggshell concentrations of heavy metals and other elements was also investigated, and the concentrations of the elements showed the following pattern: Ca > Mg > Sr > Fe > Zn > Al > Cr > Se > Mn > Cu > Pb > As > Ni > Mo = V > Sc > Cd. The concentrations of Fe, Al, and Mn decreased with the order in which the eggs were laid, but Sr concentrations increased. In contrast, the concentration of Cu significantly increased with the laying date. The concentrations of all elements significantly differed among the studied colonies; the highest concentration of eight elements was found in the eggshells from the Kusowo colony, which may have resulted from the intensive use of fertilizers, manure, and slurry in the surrounding agricultural region. The concentrations of Mg, Sr, and Zn in the eggshells from Skoki Duże were higher than those of the other studied colonies, which may have occurred because the gulls were nesting in a functioning gravel pit; soil and the parent rock are natural reservoirs of these elements. The observed element levels indicate that the environment where the black-headed gull eggs were formed, i.e., primarily near the breeding colonies, remains in a relatively unpolluted state, which was reflected by the low levels of Cd, Ni, and Pb and the lack of measurable levels of Hg.

  13. Developmental plasticity in reptiles: Insights into thermal and maternal effects on chameleon phenotypes.

    Science.gov (United States)

    Andrews, Robin M

    2018-04-23

    Embryonic environments affect a range of phenotypic traits including sex and reproductive success. I determined (1) how the interaction between incubation temperature and egg size affects sex allocation of Chamaeleo calyptratus and (2) how incubation temperature and maternal parent (clutch) affect water uptake by eggs and body size, growth, and climbing speed of hatchlings and juveniles. Eggs from five clutches were exposed to five temperature treatments with clutches replicated within and among treatments. Temperature affected sex, but only when egg size was included as a factor in analyses. At intermediate (28°C) temperatures, daughters were more likely to be produced from large eggs and sons more likely to be produced from small eggs, while at 25 and 30°C, the pattern of sex allocation was reversed. Temperature and clutch affected water uptake and body size. Nonetheless, the direction of temperature and clutch effects on water uptake by eggs and on the size of hatchlings were not the same and the direction of temperature effects on body sizes of hatchlings and juveniles differed as well. Clutch affected hatchling size but not juvenile size and growth rate. Clutch, but not incubation temperature, affected climbing speed, but the fastest hatchlings were not from the same clutches as the fastest juveniles. The independent effects of incubation temperature and clutch indicate that hatchling phenotypes are influenced largely by conditions experienced during incubation, while juvenile phenotypes are influenced largely by conditions experienced in the rearing environment. © 2018 Wiley Periodicals, Inc.

  14. In Search of Insight.

    Science.gov (United States)

    Kaplan, Craig A.; Simon, Herbert A.

    1990-01-01

    Attaining the insight needed to solve the Mutilated Checkerboard problem, which requires discovery of an effective problem representation (EPR), is described. Performance on insight problems can be predicted from the availability of generators and constraints in the search for an EPR. Data for 23 undergraduates were analyzed. (TJH)

  15. Dreaming and insight

    Science.gov (United States)

    Edwards, Christopher L.; Ruby, Perrine M.; Malinowski, Josie E.; Bennett, Paul D.; Blagrove, Mark T.

    2013-01-01

    This paper addresses claims that dreams can be a source of personal insight. Whereas there has been anecdotal backing for such claims, there is now tangential support from findings of the facilitative effect of sleep on cognitive insight, and of REM sleep in particular on emotional memory consolidation. Furthermore, the presence in dreams of metaphorical representations of waking life indicates the possibility of novel insight as an emergent feature of such metaphorical mappings. In order to assess whether personal insight can occur as a result of the consideration of dream content, 11 dream group discussion sessions were conducted which followed the Ullman Dream Appreciation technique, one session for each of 11 participants (10 females, 1 male; mean age = 19.2 years). Self-ratings of deepened self-perception and personal gains from participation in the group sessions showed that the Ullman technique is an effective procedure for establishing connections between dream content and recent waking life experiences, although wake life sources were found for only 14% of dream report text. The mean Exploration-Insight score on the Gains from Dream Interpretation questionnaire was very high and comparable to outcomes from the well-established Hill (1996) therapist-led dream interpretation method. This score was associated between-subjects with pre-group positive Attitude Toward Dreams (ATD). The need to distinguish “aha” experiences as a result of discovering a waking life source for part of a dream, from “aha” experiences of personal insight as a result of considering dream content, is discussed. Difficulties are described in designing a control condition to which the dream report condition can be compared. PMID:24550849

  16. OpenGL Insights

    CERN Document Server

    Cozzi, Patrick

    2012-01-01

    Get Real-World Insight from Experienced Professionals in the OpenGL Community With OpenGL, OpenGL ES, and WebGL, real-time rendering is becoming available everywhere, from AAA games to mobile phones to web pages. Assembling contributions from experienced developers, vendors, researchers, and educators, OpenGL Insights presents real-world techniques for intermediate and advanced OpenGL, OpenGL ES, and WebGL developers. Go Beyond the Basics The book thoroughly covers a range of topics, including OpenGL 4.2 and recent extensions. It explains how to optimize for mobile devices, explores the design

  17. World energy insight 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-15

    The World Energy Insight 2011 is the official publication of the World Energy Council. It includes interviews, articles and case studies from a distinguished panel of World Energy Council Officers, CEOs, government ministers, academics and opinion formers from all areas of the energy sector and provides perspectives from around the globe. Government, industry and NGO's offer both policy and technology perspectives. The insights within this publication add to the work that WEC is doing to provide the forum for energy leaders, along with the on-going WEC studies and programmes on Energy Policies, 2050 Energy Scenarios, Energy Resources & Technologies, Energy for Urban Innovation, Rules Of Energy Trade and Global Energy Access.

  18. Global China Insights

    NARCIS (Netherlands)

    Segers, Rien; Fischer, Ingrid

    Journal in which the Groningen Confucius Institute (GCI) shares different perspectives on China and provides insights into China from as many different aspects as possible. GCI aims to provide a full view of real China to the readers as well as featuring international and comprehensive perspectives,

  19. Global China Insights

    NARCIS (Netherlands)

    Segers, Rien; Havinga, Marieke; Fischer, Ingrid

    2013-01-01

    Journal in which the Groningen Confucius Institute (GCI) shares different perspectives on China and provides insights into China from as many different aspects as possible. GCI aims to provide a full view of real China to the readers as well as featuring international and comprehensive perspectives,

  20. Africa Insight: Submissions

    African Journals Online (AJOL)

    Author Guidelines. Africa Insight is a quarterly, peer-reviewed journal of the Africa Institute of South Africa (AISA). It is accredited by the Department of Higher ... Abstract: All articles should be accompanied by an abstract of between 100 and 125 words stating the main research problem, major findings and conclusion(s).

  1. [Poor insight and psychosis].

    Science.gov (United States)

    Giotakos, O

    2017-01-01

    A variety of phenomena might be considered as reflecting impaired insight in psychosis, like failure to recognize signs, symptoms or disease, failure to derive appropriate cognitive representations, despite recognition of the disease, and misattribution of the source or cause of the disease. The unawareness of tardive dyskinesia symptoms in schizophrenic patients points that self-awareness deficits in schizophrenia may be domain specific. Poor insight is an independent phenomenological and a prevalent feature in psychotic disorders in general, and in schizophrenia in particular, but we don't know yet if delusions in schizophrenia are the result of an entirely normal attempt to account for abnormal perceptual experiences or a product of abnormal experience but of normal reasoning. The theoretical approaches regarding impaired insight include the disturbed perceptual input, the impaired linkage between thought and emotion and the breakdown of the process of self-monitoring and error checking. The inability to distinguish between internally and externally generated mental events has been described by the metarepresentation theory. This theory includes the awareness of ones' goals, which leads to disorders of willed action, the awareness of intention, which leads to movement disorders, and the awareness of intentions of others, which leads to paranoid delusions. The theory of metarepresentation implies mainly output mechanisms, like the frontal cortex, while the input mechanism implies posterior brain systems, including the parietal lobe. There are many similarities between the disturbances of awareness seen in schizophrenia and those seen as a result of known neurological impairment. Neuropsychological models of impaired insight typically attribute the disturbance to any of a variety of core deficits in the processing of information. In this respect, lack of insight is on conceptual par with alogia, apraxia or aphasia in reflecting disturbed cognitive processing. In

  2. World energy insight 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-15

    The World Energy Insight 2011 is the official publication of the World Energy Council. It includes interviews, articles and case studies from a distinguished panel of World Energy Council Officers, CEOs, government ministers, academics and opinion formers from all areas of the energy sector and provides perspectives from around the globe. Government, industry and NGO's offer both policy and technology perspectives. The insights within this publication add to the work that WEC is doing to provide the forum for energy leaders, along with the on-going WEC studies and programmes on Energy Policies, 2050 Energy Scenarios, Energy Resources & Technologies, Energy for Urban Innovation, Rules Of Energy Trade and Global Energy Access.

  3. The politics of insight

    OpenAIRE

    Salvi, Carola; Cristofori, Irene; Grafman, Jordan; Beeman, Mark

    2016-01-01

    Previous studies showed that liberals and conservatives differ in cognitive style. Liberals are more flexible, and tolerant of complexity and novelty, whereas conservatives are more rigid, are more resistant to change, and prefer clear answers. We administered a set of compound remote associate problems, a task extensively used to differentiate problem-solving styles (via insight or analysis). Using this task, several researches have proven that self-reports, which differentiate between insig...

  4. HPC Insights, Fall 2011

    Science.gov (United States)

    2011-01-01

    Power 6 ( Davinci ) systems. We have also made use of the Air Force Research Laboratory DSRC Altix (Hawk) and the Engineer Research and Development...the design and development of high performance gas turbine combustion systems both as a pretest analysis tool to predict static and dynamic...application while gaining insight into MATLAB’s value as an engineering tool . I would like to thank the MHPCC and the Akamai Workforce Initiative

  5. The politics of insight.

    Science.gov (United States)

    Salvi, Carola; Cristofori, Irene; Grafman, Jordan; Beeman, Mark

    2016-01-01

    Previous studies showed that liberals and conservatives differ in cognitive style. Liberals are more flexible, and tolerant of complexity and novelty, whereas conservatives are more rigid, are more resistant to change, and prefer clear answers. We administered a set of compound remote associate problems, a task extensively used to differentiate problem-solving styles (via insight or analysis). Using this task, several researches have proven that self-reports, which differentiate between insight and analytic problem-solving, are reliable and are associated with two different neural circuits. In our research we found that participants self-identifying with distinct political orientations demonstrated differences in problem-solving strategy. Liberals solved significantly more problems via insight instead of in a step-by-step analytic fashion. Our findings extend previous observations that self-identified political orientations reflect differences in cognitive styles. More specifically, we show that type of political orientation is associated with problem-solving strategy. The data converge with previous neurobehavioural and cognitive studies indicating a link between cognitive style and the psychological mechanisms that mediate political beliefs.

  6. The politics of insight

    Science.gov (United States)

    Salvi, Carola; Cristofori, Irene; Grafman, Jordan; Beeman, Mark

    2016-01-01

    Previous studies showed that liberals and conservatives differ in cognitive style. Liberals are more flexible, and tolerant of complexity and novelty, whereas conservatives are more rigid, are more resistant to change, and prefer clear answers. We administered a set of compound remote associate problems, a task extensively used to differentiate problem-solving styles (via insight or analysis). Using this task, several researches have proven that self-reports, which differentiate between insight and analytic problem-solving, are reliable and are associated with two different neural circuits. In our research we found that participants self-identifying with distinct political orientations demonstrated differences in problem-solving strategy. Liberals solved significantly more problems via insight instead of in a step-by-step analytic fashion. Our findings extend previous observations that self-identified political orientations reflect differences in cognitive styles. More specifically, we show that type of political orientation is associated with problem-solving strategy. The data converge with previous neurobehavioural and cognitive studies indicating a link between cognitive style and the psychological mechanisms that mediate political beliefs. PMID:26810954

  7. What are System Dynamics Insights?

    OpenAIRE

    Stave, K.; Zimmermann, N. S.; Kim, H.

    2016-01-01

    This paper explores the concept of system dynamics insights. In our field, the term “insight” is generally understood to mean dynamic insight, that is, a deep understanding about the relationship between structure and behavior. We argue this is only one aspect of the range of insights possible from system dynamics activities, and describe a broader range of potential system dynamics insights. We also propose an initial framework for discussion that relates different types of system dynamics a...

  8. Insight in seasonal affective disorder.

    Science.gov (United States)

    Ghaemi, S N; Sachs, G S; Baldassano, C F; Truman, C J

    1997-01-01

    Lack of insight complicates the evaluation and treatment of patients with psychotic and affective disorders. No studies of insight in seasonal affective disorder (SAD) have been reported. Thirty patients with SAD diagnosed by the Structured Clinical Interview for DSM-III-R but no other axis I conditions were treated short-term with light-therapy. Insight was measured with the Scale to Assess Unawareness of Mental Disorder (SUMD) as modified by the authors to assess the self-report of insight into depressive symptoms. Increasing scores (1 to 5) indicated increasing unawareness of illness (i.e., less insight). SAD patients displayed a moderate amount of insight when depressed (mean SUMD score, 2.5). When recovered, they showed no significant change in insight into past depressive symptoms (mean SUMD score, 2.8). Greater insight into current depressive symptoms correlated with more depressive symptoms on the Hamilton Rating Scale for Depression score ([HRSD] r = .35, P depressive symptoms that does not change after recovery, a result in agreement with studies of insight in psychosis and mania. Further, in SAD, increased severity of illness may be associated with increased insight into depressive symptoms, consistent with the hypothesis of depressive realism.

  9. Insights on STEM Careers

    Energy Technology Data Exchange (ETDEWEB)

    Wendelberger, Joanne Roth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-05

    This presentation will provide career advice for individuals seeking to go beyond just having a job to building a successful career in the areas of Science, Technology, Engineering, and Mathematics. Careful planning can be used to turn a job into a springboard for professional advancement and personal satisfaction. Topics to be addressed include setting priorities, understanding career ladders, making tough choices, overcoming stereotypes and assumptions by others, networking, developing a professional identify, and balancing a career with family and other personal responsibilities. Insights on the transition from individual technical work to leadership will also be provided. The author will draw upon experiences gained in academic, industrial, and government laboratory settings, as well as extensive professional service and community involvement.

  10. Osho - Insights on sex.

    Science.gov (United States)

    Nagaraj, Anil Kumar Mysore

    2013-01-01

    Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later wanted himself to be called Osho, is a great master. He has spoken volumes on a wide range of topics ranging from sex to super-consciousness. His contributions in the area of sex are based on the principles of "Tantra" which has its origin from Buddhism. This article focuses on his life and insights on sex, which if understood properly, can be a stepping stone for enlightenment.

  11. Outsourcing/Offshoring Insights

    DEFF Research Database (Denmark)

    Tate, Wendy; Bals, Lydia

    2017-01-01

    Findings: Both the geographical and governance dimensions are part of the rightshoring decision which is an important conceptual foundation for this special issue, as it invited insightful pieces on all of these phenomena (e.g. outsourcing, insourcing, offshoring, reshoring), acknowledging...... for future research out of the six papers are summarized in Table III. There is ample opportunity to further shed light on these suggestions as well as to cover parts of the “rightshoring” framework presented, that remain less covered here (e.g. insourcing and/or reshoring). Practical implications: The array...... of potential “rightshoring” options fosters clarity about the phenomena studied and their implications. The main practical implications of the six papers are summarized in Table II. Originality/value: The overall conceptual framework highlights the positioning of the final papers included into the special...

  12. Insights into business student's book

    CERN Document Server

    Lannon, Michael; Trappe, Tonya

    1993-01-01

    With Challenging reading and listening texts from a range of authentic business sources, New Insights into Business will really engage your students. The thorough language and vocabulary syllabus together with the strong focus on business skills development gives students everything they need to function effectively in the workplace. New Insights into Business is a self-contained course and is also an ideal follow-on to First Insights into Business.

  13. Insight in schizophrenia: a review.

    Science.gov (United States)

    Dam, Jesper

    2006-01-01

    The issue of insight in schizophrenia must be assumed to be one of the most important aspects of the clinical examination. Comprehensive studies have shown that between 50% and 80% of all patients suffering from schizophrenia do not believe that they have a disorder. In recent years, poor insight in schizophrenia has been the subject of increasing interest, as manifested in a number of studies discussed in the present review. Some of these studies focus on insight correlated to various parameters such as psychopathology, neuropsychology, clinical relevance and compliance. Other studies refer to more theoretical implications, among these the issue of defining the concept of insight: whether insight can be seen as a "primary" phenomenon in schizophrenia, and whether insight may be graduated, dimensioned or increased. Several authors have developed rating scales in an attempt to obtain a measure for the degree or dimension of insight. Here, the range of parameters employed gives an excellent impression of the complexity of the concept of insight. In the concluding discussion, a phenomenological aspect is brought in, in an attempt to place the concept of insight in relation to disturbances of the self in schizophrenia and to primary symptoms in schizophrenia, amongst these autism.

  14. Mechanical design of a free-wheel clutch for the thermal engine of a parallel hybrid vehicle with thermal and electrical power-train; Conception mecanique d'un accouplement a roue libre pour le moteur thermique d'un vehicule hybride parallele thermique et electrique

    Energy Technology Data Exchange (ETDEWEB)

    Santin, J.J.

    2001-07-01

    This thesis deals with the design of a free-wheel clutch. This unit is intended to replace the automated dry single-plate clutch of a parallel hybrid car with thermal and electric power-train. Furthermore, the car is a single shaft zero emission vehicle fitted with a controlled gearbox. Chapter one focuses on the type of hybrid vehicle studied. It shows the need to isolate the engine from the rest of the drive train, depending on the driving conditions. Chapter two presents and compares the two alternatives: automated clutch and free-wheel. In order to develop the free-wheel option, the torsional vibrations in the automotive drive line had to be closely studied. It required the design of a specific modular tool, as presented in chapter three, with the help of MATLAB SIMULINK. Lastly, chapter four shows how this tool was used during the design stage and specifies the way to build it. The free-wheel is then to be fitted to a prototype hybrid vehicle, constructed by both the LAMIH and PSA. (author)

  15. A fly-wheel drive with controlled-torque clutch for a reactors cooling circuit pumps; Entrainement des pompes du circuit de refrigeration d'un reacteur par volant a embrayage sous couple controle

    Energy Technology Data Exchange (ETDEWEB)

    Riettini, A [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1964-10-15

    After a theoretical study on the slowing down of a centrifugal pump, the motion equations have been checked by means of experimental tests. In order to have important slowing down times (which is the case of the cooling pumps of a research reactor) it is necessary to add a fly-wheel. To prevent troubles when starting, a block pump-fly-wheel with clutch under controlled torque was developed. It is so possible to start the fly-wheel progressively without increasing too much power of the driving motor. (author) [French] Apres une etude theorique sur le mouvement de ralentissement d'une pompe centrifuge, les equations du mouvement ont ete verifiees par des essais pratiques. Pour obtenir des temps de ralentissement importants (cas des pompes de refrigeration d'un reacteur de recherche) il est necessaire d'y adjoindre un volant d'inertie. Pour eviter les inconvenients au demarrage, on a etudie un ensemble pompe-volant avec embrayage sous couple controle. Cette solution permet de lancer progressivement le volant sans augmentation appreciable de la puissance du moteur d'entrainement. (auteur)

  16. Eggshell Porosity Provides Insight on Evolution of Nesting in Dinosaurs.

    Directory of Open Access Journals (Sweden)

    Kohei Tanaka

    Full Text Available Knowledge about the types of nests built by dinosaurs can provide insight into the evolution of nesting and reproductive behaviors among archosaurs. However, the low preservation potential of their nesting materials and nesting structures means that most information can only be gleaned indirectly through comparison with extant archosaurs. Two general nest types are recognized among living archosaurs: 1 covered nests, in which eggs are incubated while fully covered by nesting material (as in crocodylians and megapodes, and 2 open nests, in which eggs are exposed in the nest and brooded (as in most birds. Previously, dinosaur nest types had been inferred by estimating the water vapor conductance (i.e., diffusive capacity of their eggs, based on the premise that high conductance corresponds to covered nests and low conductance to open nests. However, a lack of statistical rigor and inconsistencies in this method render its application problematic and its validity questionable. As an alternative we propose a statistically rigorous approach to infer nest type based on large datasets of eggshell porosity and egg mass compiled for over 120 extant archosaur species and 29 archosaur extinct taxa/ootaxa. The presence of a strong correlation between eggshell porosity and nest type among extant archosaurs indicates that eggshell porosity can be used as a proxy for nest type, and thus discriminant analyses can help predict nest type in extinct taxa. Our results suggest that: 1 covered nests are likely the primitive condition for dinosaurs (and probably archosaurs, and 2 open nests first evolved among non-avian theropods more derived than Lourinhanosaurus and were likely widespread in non-avian maniraptorans, well before the appearance of birds. Although taphonomic evidence suggests that basal open nesters (i.e., oviraptorosaurs and troodontids were potentially the first dinosaurs to brood their clutches, they still partially buried their eggs in sediment

  17. Eggshell Porosity Provides Insight on Evolution of Nesting in Dinosaurs.

    Science.gov (United States)

    Tanaka, Kohei; Zelenitsky, Darla K; Therrien, François

    2015-01-01

    Knowledge about the types of nests built by dinosaurs can provide insight into the evolution of nesting and reproductive behaviors among archosaurs. However, the low preservation potential of their nesting materials and nesting structures means that most information can only be gleaned indirectly through comparison with extant archosaurs. Two general nest types are recognized among living archosaurs: 1) covered nests, in which eggs are incubated while fully covered by nesting material (as in crocodylians and megapodes), and 2) open nests, in which eggs are exposed in the nest and brooded (as in most birds). Previously, dinosaur nest types had been inferred by estimating the water vapor conductance (i.e., diffusive capacity) of their eggs, based on the premise that high conductance corresponds to covered nests and low conductance to open nests. However, a lack of statistical rigor and inconsistencies in this method render its application problematic and its validity questionable. As an alternative we propose a statistically rigorous approach to infer nest type based on large datasets of eggshell porosity and egg mass compiled for over 120 extant archosaur species and 29 archosaur extinct taxa/ootaxa. The presence of a strong correlation between eggshell porosity and nest type among extant archosaurs indicates that eggshell porosity can be used as a proxy for nest type, and thus discriminant analyses can help predict nest type in extinct taxa. Our results suggest that: 1) covered nests are likely the primitive condition for dinosaurs (and probably archosaurs), and 2) open nests first evolved among non-avian theropods more derived than Lourinhanosaurus and were likely widespread in non-avian maniraptorans, well before the appearance of birds. Although taphonomic evidence suggests that basal open nesters (i.e., oviraptorosaurs and troodontids) were potentially the first dinosaurs to brood their clutches, they still partially buried their eggs in sediment. Open nests

  18. Insights into PRA methodologies

    International Nuclear Information System (INIS)

    Gallagher, D.; Lofgren, E.; Atefi, B.; Liner, R.; Blond, R.; Amico, P.

    1984-08-01

    Probabilistic Risk Assessments (PRAs) for six nuclear power plants were examined to gain insight into how the choice of analytical methods can affect the results of PRAs. The PRA sreflectope considered was limited to internally initiated accidents sequences through core melt. For twenty methodological topic areas, a baseline or minimal methodology was specified. The choice of methods for each topic in the six PRAs was characterized in terms of the incremental level of effort above the baseline. A higher level of effort generally reflects a higher level of detail or a higher degree of sophistication in the analytical approach to a particular topic area. The impact on results was measured in terms of how additional effort beyond the baseline level changed the relative importance and ordering of dominant accident sequences compared to what would have been observed had methods corresponding to the baseline level of effort been employed. This measure of impact is a more useful indicator of how methods affect perceptions of plant vulnerabilities than changes in core melt frequency would be. However, the change in core melt frequency was used as a secondary measure of impact for nine topics where availability of information permitted. Results are presented primarily in the form of effort-impact matrices for each of the twenty topic areas. A suggested effort-impact profile for future PRAs is presented

  19. Grigor Narekatsi's astronomical insights

    Science.gov (United States)

    Poghosyan, Samvel

    2015-07-01

    What stand out in the solid system of Gr. Narekatsi's naturalistic views are his astronomical insights on the material nature of light, its high speed and the Sun being composed of "material air". Especially surprising and fascinating are his views on stars and their clusters. What astronomers, including great Armenian academician V. Ambartsumian (scattering of stellar associations), would understand and prove with much difficulty thousand years later, Narekatsi predicted in the 10th century: "Stars appear and disappear untimely", "You who gather and scatter the speechless constellations, like a flock of sheep". Gr. Narekatsti's reformative views were manifested in all the spheres of the 10th century social life; he is a reformer of church life, great language constructor, innovator in literature and music, freethinker in philosophy and science. His ideology is the reflection of the 10th century Armenian Renaissance. During the 9th-10th centuries, great masses of Armenians, forced to migrate to the Balkans, took with them and spread reformative ideas. The forefather of the western science, which originated in the period of Reformation, is considered to be the great philosopher Nicholas of Cusa. The study of Gr. Narekatsti's logic and naturalistic views enables us to claim that Gr. Narekatsti is the great grandfather of European science.

  20. O insight em psiquiatria

    Directory of Open Access Journals (Sweden)

    Ana Margarida P. Cardoso

    2008-12-01

    Full Text Available O sinal de que algo está a acontecer contribui para que o paciente reconheça que alguma coisa de estranho se está a passar consigo. Este reconhecimento faz com que o sujeito possa desempenhar uma função activa e seja um elemento colaborante do seu processo de recuperação. Cada doença apresenta, contudo, diferentes sintomas, uma vez que cada doença psiquiátrica consiste em diferentes perturbações com diversos efeitos sobre o funcionamento mental. Desta maneira, o fenómeno do insight que é registado em cada doença é diferente e expressa-se sob diferentes formas, não somente devido às manifestações clínicas da doença mas também devido às características individuais do sujeito.

  1. Cognitive insight: A systematic review.

    Science.gov (United States)

    Van Camp, L S C; Sabbe, B G C; Oldenburg, J F E

    2017-07-01

    Cognitive insight is the ability to re-evaluate thoughts and beliefs in order to make thoughtful conclusions. It differs from clinical insight, as it focuses on more general metacognitive processes. Therefore, it could be relevant to diverse disorders and non-clinical subjects. There is a growing body of research on cognitive insight in individuals with and without psychosis. This review has summarised the current state of the art regarding this topic. We conclude that while cognitive insight in its current form seems valid for use in individuals with psychosis, it is less so for individuals without psychosis. Additionally, higher cognitive insight not always leads to better psychological functioning. For instance, higher levels of self-reflection are often associated with depressive mood. We therefore recommend the sub-components of cognitive insight to be studied separately. Also, it is unclear what position cognitive insight takes within the spectrum of metacognitive processes and how it relates to other self-related concepts that have been defined previously in literature. Combining future and past research on cognitive insight and its analogue concepts will help in the formation of a uniform definition that fits all subjects discussed here. Copyright © 2017. Published by Elsevier Ltd.

  2. Hyperons: Insights into baryon structures

    International Nuclear Information System (INIS)

    Lach, J.

    1991-08-01

    The baryon octet is composed mainly of hyperons. Modern high energy hyperon beams provide a tool for the study of hyperon static properties and interactions. Experiments with these beams have provided new insights into hyperon rare decays, magnetic moments, and interactions. These experiments provide us with insights into the strong, weak, and electromagnetic structure of the baryons. 65 refs., 45 figs., 5 tabs

  3. How nest translocation-time, clutch size and presence of yolkless eggs affected hatching success in Dermochelys coriacea (Linnaeus, 1766 (Testudines: Dermochelyidae, at Projeto Tamar-Ibama, Espirito Santo, Brazil

    Directory of Open Access Journals (Sweden)

    Dal Pont Morisso, Eduardo

    2004-07-01

    Full Text Available En este estudio se analizó el manejo de los nidos de la especie Dermochelys coriacea, utilizados por el Proyecto Tamar-Ibama entre las temporadas reproductivas de 1989/1990 a 1998/1999, para verificación del éxito de la eclosión en relación a los tiempos de traslación. El estudio se realizó en el litoral norte del Estado de Espírito Santo. Existió tendencia a que el tiempo de traslación influencie el éxito de eclosión de los nidos. Los nidos trasladados entre 6 y más de 24 horas presentaron mayor cantidad de huevos sin desarrollo embrionario. No se encontró relación entre el número de huevos inviables trasladados y el tamaño de la postura, con el porcentual de eclosión. Se sugiere que la traslación sea realizada hasta las 6 horas, o 15 días después de la oviposición. The results of managing Dermochelys coriacea (Linnaeus, 1766 nests by Projeto TAMAR - IBAMA, in Northern Espírito Santo, Brazil, during the nesting seasons from 1989/90 to 1998/99 are analyzed. The influence of the translocation time on hatching success of the studied nests is discussed. The time translocation, in relation to natural oviposition, seems to increase the number of non-developed eggs found in each nest if translocated between 6 hours and 15 days post egg-laying. There was no relationship established between either the number of yolkless eggs in a translocated nest or the clutch size, with hatching success. The translocation of Dermochelys nests either within 6 hours or after 15 days from natural oviposition is recommended.

  4. Parental insightfulness: retrospect and prospect.

    Science.gov (United States)

    Koren-Karie, Nina; Oppenheim, David

    2018-06-01

    We open this introductory paper to the special issue with the theoretical and clinical roots of the insightfulness concept. Next, the Insightfulness Assessment (IA) is presented, followed by a review of key empirical findings supporting the IA. The central points in the papers in this special issue are reviewed next. These include the use of the IA with parents of children ranging in age from infancy to adolescence, its applicability outside the parent-child relationship (e.g. insightfulness toward a close friend), its use with high-risk mothers, and the usefulness of insightfulness both as a continuous and a categorical measure. The clinical applications of the IA are discussed, and we close with future directions for IA research.

  5. Franchise Business Model: Theoretical Insights

    OpenAIRE

    Levickaitė, Rasa; Reimeris, Ramojus

    2010-01-01

    The article is based on literature review, theoretical insights, and deals with the topic of franchise business model. The objective of the paper is to analyse peculiarities of franchise business model and its developing conditions in Lithuania. The aim of the paper is to make an overview on franchise business model and its environment in Lithuanian business context. The overview is based on international and local theoretical insights. In terms of practical meaning, this article should be re...

  6. Variation in parental investment and relative clutch mass of the spiny-tail iguana, Ctenosaura pectinata (Squamata: Iguanidae in central México Variación en la inversión parental y masa relativa de la nidada en la iguana de cola espinosa Ctenosaura pectinata (Squamata: Iguanidae en el centro de México

    Directory of Open Access Journals (Sweden)

    Rubén Castro-Franco

    2011-03-01

    Full Text Available We measured the length, width, volume, and weight of 871 freshly laid eggs of 28 clutches of Ctenosaura pectinata. The iguanas were obtained from a tropical dry forest area in central Mexico. The relative clutch mass was related positively to the average egg weight but not to average egg volume. Unlike what usually occurs in lizards, where the body length strongly predicts egg production, in C. pectinata clutch size and egg size were not correlated with female weight or snout-vent length. Observed differences revealed variation in the weight-size of the egg within an individual clutch. Therefore, there is not an optimization of the egg in the studied population of Ctenosaura, as usually occurs in small lizards. This variation associated with reproduction takes place in the middle of the dry season, and may be interpreted as an adaptation to facilitate the adjustment of different phenotypes in environments with extreme drought.Medimos la longitud, amplitud, volumen, y peso de 871 huevos recién puestos de 28 nidadas de Ctenosaura pectinata. Las iguanas fueron obtenidas en un área de bosque tropical seco en el centro de México. La masa relativa de la nidada estuvo relacionada positivamente con el peso promedio de los huevos pero no con el volumen promedio del huevo. A diferencia de lo que ocurre usualmente en lagartijas, donde la longitud del cuerpo determina la producción de huevos, en C. pectinata el tamaño de la puesta y el tamaño del huevo no se correlacionan con el peso y tamaño de las hembras. Las diferencias observadas revelan variación en el tamaño y peso de los huevos dentro de las puestas individuales. En consecuencia, no hay una optimización del huevo en la población estudiada de Ctenosaura, como usualmente ocurre en lagartijas de tamaño pequeño. Esta variación asociada con la reproducción tiene lugar a mitad de la estación seca, y puede ser interpretada como una adaptación para facilitar el ajuste de diferentes

  7. Understanding Insight in the Context of Q

    Science.gov (United States)

    Coghlan, David

    2012-01-01

    In Revans' learning formula, L = P + Q, Q represents "questioning insight", by which Revans means that insight comes out of the process of questioning programmed knowledge (P) in the light of experience. We typically focus on the content of an insight rather than on the act of insight. Drawing primarily on the work of Bernard Lonergan this paper…

  8. Approaching the Distinction between Intuition and Insight.

    Science.gov (United States)

    Zhang, Zhonglu; Lei, Yi; Li, Hong

    2016-01-01

    Intuition and insight share similar cognitive and neural basis. Though, there are still some essential differences between the two. Here in this short review, we discriminated between intuition, and insight in two aspects. First, intuition, and insight are toward different aspects of information processing. Whereas intuition involves judgment about "yes or no," insight is related to "what" is the solution. Second, tacit knowledge play different roles in between intuition and insight. On the one hand, tacit knowledge is conducive to intuitive judgment. On the other hand, tacit knowledge may first impede but later facilitate insight occurrence. Furthermore, we share theoretical, and methodological views on how to access the distinction between intuition and insight.

  9. Insight in psychosis: Metacognitive processes and treatment

    OpenAIRE

    de Vos, Annerieke

    2016-01-01

    Insight is impaired in 50- 80% of the patients with schizophrenia. Annerieke de Vos working at GGZ Drenthe and the University Medical Hospital Groningen, aimed to elucidate which processes underlie impaired insight and tried to improve insight in patients by targeting these processes. On September 21st she will defend her thesis entitled: "Insight in psychosis. Metacognitive processes and treatment.". Patients with impaired insight may fail to recognize that things in life are not going well ...

  10. Clutches and brakes design and selection

    CERN Document Server

    Orthwein, William C

    2004-01-01

    FRICTION MATERIALSFriction CodeWearBrake FadeFriction MaterialsNotationReferencesBAND BRAKESDerivation of EquationsApplicationLever-Actuated Band Brake: Backstop DesignExample: Design of a BackstopNotationFormula CollectionReferencesEXTERNALLY AND INTERNALLY PIVOTED SHOE BRAKESPivoted External Drum BrakesPivoted Internal Drum BrakesDesign of Dual-Anchor Twin-Shoe Drum BrakesDual-Anchor Twin-Shoe Drum Brake Design ExamplesDesign of Single-Anchor Twin-Shoe Drum BrakesSingle-Anchor Twin-Shoe Drum Brake Design Exam

  11. New Insights into Behavioral Finance

    NARCIS (Netherlands)

    G. Baltussen (Guido)

    2008-01-01

    textabstractThis thesis applies insights from psychology and other behavioral sciences to overcome the shortcomings of the traditional finance approach (which assumes that agents and markets are rational) and improves our understanding of financial markets and its participants. More specific, this

  12. Investigating Insight as Sudden Learning

    Science.gov (United States)

    Ash, Ivan K.; Jee, Benjamin D.; Wiley, Jennifer

    2012-01-01

    Gestalt psychologists proposed two distinct learning mechanisms. Associative learning occurs gradually through the repeated co-occurrence of external stimuli or memories. Insight learning occurs suddenly when people discover new relationships within their prior knowledge as a result of reasoning or problem solving processes that re-organize or…

  13. Insight in psychosis : Metacognitive processes and treatment

    NARCIS (Netherlands)

    de Vos, Annerieke

    2016-01-01

    Insight is impaired in 50- 80% of the patients with schizophrenia. Annerieke de Vos working at GGZ Drenthe and the University Medical Hospital Groningen, aimed to elucidate which processes underlie impaired insight and tried to improve insight in patients by targeting these processes. On September

  14. Quantifying the Qualitative: Measuring the Insight Experience

    Science.gov (United States)

    Jarman, Matthew S.

    2014-01-01

    No scales currently exist that measure variability in the insight experience. Two scales were created to measure two factors hypothesized to be key drivers of the insight experience: insight radicality (i.e., perceived deviation between previous and new problem representations) and restructuring experience (i.e., the subjective experience of the…

  15. GOES-R: Satellite Insight

    Science.gov (United States)

    Fitzpatrick, Austin J.; Leon, Nancy J.; Novati, Alexander; Lincoln, Laura K.; Fisher, Diane K.

    2012-01-01

    GOES-R: Satellite Insight seeks to bring awareness of the GOES-R (Geostationary Operational Environmental Satellite -- R Series) satellite currently in development to an audience of all ages on the emerging medium of mobile games. The iPhone app (Satellite Insight) was created for the GOES-R Program. The app describes in simple terms the types of data products that can be produced from GOES-R measurements. The game is easy to learn, yet challenging for all audiences. It includes educational content and a path to further information about GOESR, its technology, and the benefits of the data it collects. The game features action-puzzle game play in which the player must prevent an overflow of data by matching falling blocks that represent different types of GOES-R data. The game adds more different types of data blocks over time, as long as the player can prevent a data overflow condition. Points are awarded for matches, and players can compete with themselves to beat their highest score.

  16. Theory of mind correlates with clinical insight but not cognitive insight in patients with schizophrenia.

    Science.gov (United States)

    Zhang, Qi; Li, Xu; Parker, Giverny J; Hong, Xiao-Hong; Wang, Yi; Lui, Simon S Y; Neumann, David L; Cheung, Eric F C; Shum, David H K; Chan, Raymond C K

    2016-03-30

    Research on the relationship between insight and social cognition, in particular Theory of Mind (ToM), in schizophrenia has yielded mixed findings to date. Very few studies, however, have assessed both clinical insight and cognitive insight when examining their relationships with ToM in schizophrenia. The current study thus investigated the relationship between clinical insight, cognitive insight, and ToM in a sample of 56 patients with schizophrenia and 30 healthy controls. Twenty-seven patients were classified as low in clinical insight according to their scores on the 'insight' item (G12) of the Positive and Negative Syndrome Scale (PANSS). Moreover, cognitive insight and ToM were assessed with the Beck Cognitive Insight Scale (BCIS) and the Yoni task, respectively. The results indicated that patients with poor clinical insight performed worse on tasks of second-order cognitive and affective ToM, while the ToM performance of patients with high clinical insight was equivalent to that of healthy controls. Furthermore, while clinical insight was correlated with ToM and clinical symptoms, cognitive insight did not correlate with clinical insight, ToM, or clinical symptoms. Clinical insight thus appears to be an important factor related to ToM in schizophrenia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Managing complexity insights, concepts, applications

    CERN Document Server

    Helbing, Dirk

    2007-01-01

    Each chapter in Managing Complexity focuses on analyzing real-world complex systems and transferring knowledge from the complex-systems sciences to applications in business, industry and society. The interdisciplinary contributions range from markets and production through logistics, traffic control, and critical infrastructures, up to network design, information systems, social conflicts and building consensus. They serve to raise readers' awareness concerning the often counter-intuitive behavior of complex systems and to help them integrate insights gained in complexity research into everyday planning, decision making, strategic optimization, and policy. Intended for a broad readership, the contributions have been kept largely non-technical and address a general, scientifically literate audience involved in corporate, academic, and public institutions.

  18. Do behavioural insights matter for competition policy?

    OpenAIRE

    CIRIOLO Emanuele

    2016-01-01

    Behavioural insights make use of behavioural economics and psychology to analyse how humans behave when adopting economic decisions. The use of behavioural insights to improve policy-making is becoming increasing popular all over the world. Pensions, taxes, unemployment, energy efficiency, adult education, charitable giving and, of course, competition policy have benefitted from the application of behavioural insights. Emanuele Ciriolo, from the European Commission Joint Research Centre, expl...

  19. Genetic correlates of insight in schizophrenia.

    Science.gov (United States)

    Xavier, Rose Mary; Vorderstrasse, Allison; Keefe, Richard S E; Dungan, Jennifer R

    2018-05-01

    Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight. Schizophrenia case-only analysis of the Clinical Antipsychotics Trials of Intervention Effectiveness trial. Schizophrenia PRS was constructed using Psychiatric Genomics Consortium (PGC) leave-one out GWAS as discovery data set. For candidate regions, we selected 105 schizophrenia-associated autosomal loci and 11 schizophrenia-related oligodendrocyte genes. We used regressions to examine PRS associations and set-based testing for candidate analysis. We examined data from 730 subjects. Best-fit PRS at p-threshold of 1e-07 was associated with total insight (R 2 =0.005, P=0.05, empirical P=0.054) and treatment insight (R 2 =0.005, P=0.048, empirical P=0.048). For models that controlled for neurocognition, PRS significantly predicted treatment insight but at higher p-thresholds (0.1 to 0.5) but did not survive correction. Patients with highest polygenic burden had 5.9 times increased risk for poor insight compared to patients with lowest burden. PRS explained 3.2% (P=0.002, empirical P=0.011) of variance in poor insight. Set-based analyses identified two variants associated with poor insight- rs320703, an intergenic variant (within-set P=6e-04, FDR P=0.046) and rs1479165 in SOX2-OT (within-set P=9e-04, FDR P=0.046). To the best of our knowledge, this is the first study examining genetic basis of insight. We provide evidence for genetic contributions to impaired insight. Relevance of findings and necessity for replication are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Probabilistic safety assessment applications and insights

    International Nuclear Information System (INIS)

    Hitchler, M.J.; Burns, N.L.; Liparulo, N.J.; Mink, F.J.

    1987-01-01

    The insights gained through a comparison of seven PRA studies (Italian PUN, Sizewell B, Ringhals 2, Millstone 3, Zion 1 and 2, Oconee 3, and Seabrook) included insights regarding the adequacy of the PRA technology utilized in the studies and the potential areas for improvement and insights regarding the adequacy of plant designs and how PRA has been utilized to enhance the design and operation of nuclear power plants. (orig.)

  1. Insights gained through probabilistic risk assessments

    International Nuclear Information System (INIS)

    Hitchler, M.J.; Burns, N.L.; Liparulo, N.J.; Mink, F.J.

    1987-01-01

    The insights gained through a comparison of seven probabilistic risk assessments (PRA) studies (Italian PUN, Sizewell B, Ringhals 2, Millstone 3, Zion 1 and 2, Oconee 3, and Seabrook) included insights regarding the adequacy of the PRA technology utilized in the studies and the potential areas for improvement and insights regarding the adequacy of plant designs and how PRA has been utilized to enhance the design and operation of nuclear power plants

  2. Research Insights About Risk Governance

    Directory of Open Access Journals (Sweden)

    Therese R. Viscelli

    2016-11-01

    Full Text Available In recent years, expectations for increased risk governance have been placed explicitly on boards of directors. In response, boards are being held responsible for not only understanding and approving management’s risk management processes, but they are also being held responsible for assessing the risks identified by those processes as part of overseeing management’s pursuit of value. These increasing responsibilities have led a number of organizations to adopt enterprise risk management (ERM as a holistic approach to risk management that extends beyond traditional silo-based risk management techniques. As boards, often through their audit committee, consider management’s implementation of ERM as part of the board’s risk oversight, a number of questions emerge that can be informed by academic research related to ERM. This article summarizes findings from ERM research to provide insights related to the board’s risk governance responsibilities. We also identify a number of research questions that warrant further analysis by governance scholars. It is our hope that this article will spawn varying types of research about ERM and corporate governance.

  3. Chronic alcoholism: insights from neurophysiology.

    Science.gov (United States)

    Campanella, S; Petit, G; Maurage, P; Kornreich, C; Verbanck, P; Noël, X

    2009-01-01

    Increasing knowledge of the anatomical structures and cellular processes underlying psychiatric disorders may help bridge the gap between clinical signs and basic physiological processes. Accordingly, considerable insight has been gained in recent years into a common psychiatric condition, i.e., chronic alcoholism. We reviewed various physiological parameters that are altered in chronic alcoholic patients compared to healthy individuals--continuous electroencephalogram, oculomotor measures, cognitive event-related potentials and event-related oscillations--to identify links between these physiological parameters, altered cognitive processes and specific clinical symptoms. Alcoholic patients display: (1) high beta and theta power in the resting electroencephalogram, suggesting hyperarousal of their central nervous system; (2) abnormalities in smooth pursuit eye movements, in saccadic inhibition during antisaccade tasks, and in prepulse inhibition, suggesting disturbed attention modulation and abnormal patterns of prefrontal activation that may stem from the same prefrontal "inhibitory" cortical dysfunction; (3) decreased amplitude for cognitive event-related potentials situated along the continuum of information-processing, suggesting that alcoholism is associated with neurophysiological deficits at the level of the sensory cortex and not only disturbances involving associative cortices and limbic structures; and (4) decreased theta, gamma and delta oscillations, suggesting cognitive disinhibition at a functional level. The heterogeneity of alcoholic disorders in terms of symptomatology, course and outcome is the result of various pathophysiological processes that physiological parameters may help to define. These alterations may be related to precise cognitive processes that could be easily monitored neurophysiologically in order to create more homogeneous subgroups of alcoholic individuals.

  4. Functional Insights from Structural Genomics

    Energy Technology Data Exchange (ETDEWEB)

    Forouhar,F.; Kuzin, A.; Seetharaman, J.; Lee, I.; Zhou, W.; Abashidze, M.; Chen, Y.; Montelione, G.; Tong, L.; et al

    2007-01-01

    Structural genomics efforts have produced structural information, either directly or by modeling, for thousands of proteins over the past few years. While many of these proteins have known functions, a large percentage of them have not been characterized at the functional level. The structural information has provided valuable functional insights on some of these proteins, through careful structural analyses, serendipity, and structure-guided functional screening. Some of the success stories based on structures solved at the Northeast Structural Genomics Consortium (NESG) are reported here. These include a novel methyl salicylate esterase with important role in plant innate immunity, a novel RNA methyltransferase (H. influenzae yggJ (HI0303)), a novel spermidine/spermine N-acetyltransferase (B. subtilis PaiA), a novel methyltransferase or AdoMet binding protein (A. fulgidus AF{_}0241), an ATP:cob(I)alamin adenosyltransferase (B. subtilis YvqK), a novel carboxysome pore (E. coli EutN), a proline racemase homolog with a disrupted active site (B. melitensis BME11586), an FMN-dependent enzyme (S. pneumoniae SP{_}1951), and a 12-stranded {beta}-barrel with a novel fold (V. parahaemolyticus VPA1032).

  5. A Microgenetic Study of Insightful Problem Solving

    Science.gov (United States)

    Luwel, Koen; Siegler, Robert S.; Verschaffel, Lieven

    2008-01-01

    An eight-session microgenetic study of acquisition of an insightful problem-solving strategy was conducted. A total of 35 second graders who did not use this insightful strategy initially were assigned to two groups that differed in the frequency of problems likely to facilitate discovery and generalization of the strategy. Children in the…

  6. Mining Login Data for Actionable Student Insight

    Science.gov (United States)

    Agnihotri, Lalitha; Aghababyan, Ani; Mojarad, Shirin; Riedesel, Mark; Essa, Alfred

    2015-01-01

    Student login data is a key resource for gaining insight into their learning experience. However, the scale and the complexity of this data necessitate a thorough exploration to identify potential actionable insights, thus rendering it less valuable compared to student achievement data. To compensate for the underestimation of login data…

  7. Course of insight in manic episode

    Directory of Open Access Journals (Sweden)

    A Kumar

    2013-01-01

    Full Text Available Background: Insight is an important factor associated with non compliance and poor outcome. Poor level of insight has been described as a characteristic in patients with acute bipolar disorder with more unawareness in social consequences with increasing severity in manic episode. Aim: Main aim of study was to see the baseline and longitudinal relationship between dimensions of insight with improvement in psychopathology. Setting and Design: Forty four patients diagnosed with mania, were selected from an inpatient setting at Institute of Mental Health and Hospital, Agra with mean age of 31.07(±9.00 years. They were assessed at base line and were followed up weekly or psychopathology and insight. Materials and Methods: The Young′s mania rating scale for psychopathology and insight was assessed on three dimensions of SUMD. Results: Twenty five patients eventually completed the study. There was a positive correlation with global insight and with psychopathology consistent in longitudinal follow-up (P<0.05, but not correlating for awareness for achieved effect of medication and social consequences. Linear regression showed a positive relationship at the first and second week of assessment of SUMD and YMRS scores (P=0.001; 0.019. Conclusion: Improvement in insight is graded in a manic episode as compared to psychopathology. There is slower improvement in awareness of social consequences of mental disorder. It means that improvement in psychopathology may not necessarily indicate remission and need further supervision to improve insight and hence monitoring.

  8. Newer insights in teledermatology practice

    Directory of Open Access Journals (Sweden)

    Garehatty Rudrappa Kanthraj

    2011-01-01

    Full Text Available The study and practice of dermatology care using interactive audio, visual, and data communications from a distance is called teledermatology. A teledermatology practice (TP provides teleconsultation as well tele-education. Initially, dermatologists used videoconference. Convenience, cost-effectiveness and easy application of the practice made "store and forward" to emerge as a basic teledermatology tool. The advent of newer technologies like third generation (3G and fourth generation (4G mobile teledermatology (MT and dermatologists′ interest to adopt tertiary TP to pool expert (second opinion to address difficult-to-manage cases (DMCs has resulted in a rapid change in TP. Online discussion groups (ODGs, author-based second opinion teledermatology (AST, or a combination of both are the types of tertiary TP. This article analyzes the feasibility studies and provides latest insight into TP with a revised classification to plan and allocate budget and apply appropriate technology. Using the acronym CAP-HAT, which represents five important factors like case, approach, purpose, health care professionals, and technology, one can frame a TP. Store-and-forward teledermatology (SAFT is used to address routine cases (spotters. Chronic cases need frequent follow-up care. Leg ulcer and localized vitiligo need MT while psoriasis and leprosy require SAFT. Pigmented skin lesions require MT for triage and combination of teledermoscopy, telepathology, and teledermatology for diagnosis. A self-practising dermatologist and national health care system dermatologist use SAFT for routine cases and a combination of ASTwith an ODG to address a DMC. A TP alone or in combination with face-to-face consultation delivers quality care.

  9. Spermatogenesis in mammals: proteomic insights.

    Science.gov (United States)

    Chocu, Sophie; Calvel, Pierre; Rolland, Antoine D; Pineau, Charles

    2012-08-01

    Spermatogenesis is a highly sophisticated process involved in the transmission of genetic heritage. It includes halving ploidy, repackaging of the chromatin for transport, and the equipment of developing spermatids and eventually spermatozoa with the advanced apparatus (e.g., tightly packed mitochondrial sheat in the mid piece, elongating of the tail, reduction of cytoplasmic volume) to elicit motility once they reach the epididymis. Mammalian spermatogenesis is divided into three phases. In the first the primitive germ cells or spermatogonia undergo a series of mitotic divisions. In the second the spermatocytes undergo two consecutive divisions in meiosis to produce haploid spermatids. In the third the spermatids differentiate into spermatozoa in a process called spermiogenesis. Paracrine, autocrine, juxtacrine, and endocrine pathways all contribute to the regulation of the process. The array of structural elements and chemical factors modulating somatic and germ cell activity is such that the network linking the various cellular activities during spermatogenesis is unimaginably complex. Over the past two decades, advances in genomics have greatly improved our knowledge of spermatogenesis, by identifying numerous genes essential for the development of functional male gametes. Large-scale analyses of testicular function have deepened our insight into normal and pathological spermatogenesis. Progress in genome sequencing and microarray technology have been exploited for genome-wide expression studies, leading to the identification of hundreds of genes differentially expressed within the testis. However, although proteomics has now come of age, the proteomics-based investigation of spermatogenesis remains in its infancy. Here, we review the state-of-the-art of large-scale proteomic analyses of spermatogenesis, from germ cell development during sex determination to spermatogenesis in the adult. Indeed, a few laboratories have undertaken differential protein profiling

  10. Blindness and Insight in King Lear

    Institute of Scientific and Technical Information of China (English)

    岳元玉

    2008-01-01

    This paper intends to explore how William Shakespeare illustrates the theme of blindness and insight in his great tragedy "King Lear".Four characters’ deeds and their fate are used as a case study to examine what blindness is,what insight is,and the relationship between the two.The writer finds that by depicting the characters’ deeds and their fate in a double plot,Shakespeare renders the folly of blindness,the transition from blindness to insight,and the use of reason and thought to understand the truth.

  11. Insight Is Not in the Problem: Investigating Insight in Problem Solving across Task Types.

    Science.gov (United States)

    Webb, Margaret E; Little, Daniel R; Cropper, Simon J

    2016-01-01

    The feeling of insight in problem solving is typically associated with the sudden realization of a solution that appears obviously correct (Kounios et al., 2006). Salvi et al. (2016) found that a solution accompanied with sudden insight is more likely to be correct than a problem solved through conscious and incremental steps. However, Metcalfe (1986) indicated that participants would often present an inelegant but plausible (wrong) answer as correct with a high feeling of warmth (a subjective measure of closeness to solution). This discrepancy may be due to the use of different tasks or due to different methods in the measurement of insight (i.e., using a binary vs. continuous scale). In three experiments, we investigated both findings, using many different problem tasks (e.g., Compound Remote Associates, so-called classic insight problems, and non-insight problems). Participants rated insight-related affect (feelings of Aha-experience, confidence, surprise, impasse, and pleasure) on continuous scales. As expected we found that, for problems designed to elicit insight, correct solutions elicited higher proportions of reported insight in the solution compared to non-insight solutions; further, correct solutions elicited stronger feelings of insight compared to incorrect solutions.

  12. Impaired insight into illness and cognitive insight in schizophrenia spectrum disorders: Resting state functional connectivity

    Science.gov (United States)

    Gerretsen, Philip; Menon, Mahesh; Mamo, David C.; Fervaha, Gagan; Remington, Gary; Pollock, Bruce G.; Graff-Guerrero, Ariel

    2015-01-01

    Background Impaired insight into illness (clinical insight) in schizophrenia has negative effects on treatment adherence and clinical outcomes. Schizophrenia is described as a disorder of disrupted brain connectivity. In line with this concept, resting state networks (RSNs) appear differentially affected in persons with schizophrenia. Therefore, impaired clinical, or the related construct of cognitive insight (which posits that impaired clinical insight is a function of metacognitive deficits), may reflect alterations in RSN functional connectivity (fc). Based on our previous research, which showed that impaired insight into illness was associated with increased left hemisphere volume relative to right, we hypothesized that impaired clinical insight would be associated with increased connectivity in the DMN with specific left hemisphere brain regions. Methods Resting state MRI scans were acquired for participants with schizophrenia or schizoaffective disorder (n = 20). Seed-to-voxel and ROI-to-ROI fc analyses were performed using the CONN-fMRI fc toolbox v13 for established RSNs. Clinical and cognitive insight were measured with the Schedule for the Assessment of Insight—Expanded Version and Beck Cognitive Insight Scale, respectively, and included as the regressors in fc analyses. Results As hypothesized, impaired clinical insight was associated with increased connectivity in the default mode network (DMN) with the left angular gyrus, and also in the self-referential network (SRN) with the left insula. Cognitive insight was associated with increased connectivity in the dorsal attention network (DAN) with the right inferior frontal cortex (IFC) and left anterior cingulate cortex (ACC). Conclusion Increased connectivity in DMN and SRN with the left angular gyrus and insula, respectively, may represent neural correlates of impaired clinical insight in schizophrenia spectrum disorders, and is consistent with the literature attributing impaired insight to left

  13. Physiological and molecular insights into drought tolerance ...

    African Journals Online (AJOL)

    Physiological and molecular insights into drought tolerance. Sagadevan G Mundree, Bienyameen Baker, Shaheen Mowla, Shaun Peters, Saberi Marais, Clare Vander Willigen, Kershini Govender, Alice Maredza, Samson Muyanga, Jill M Farrant, Jennifer A Thomson ...

  14. Marketing biofortified crops: insights from consumer research ...

    African Journals Online (AJOL)

    Marketing biofortified crops: insights from consumer research. ... To develop a global strategy for consumer marketing of biofortified crops, research is needed to understand consumer ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  15. Proteus, New Insights for a New Age

    National Research Council Canada - National Science Library

    Waddell, William; Kim, Joanne; Smith, Jack

    2004-01-01

    .... The Proteus concept offers a range of new insights that, when used in the planning process, will assist military, intelligence, and industry leaders in their efforts to prepare for future success...

  16. Is Insight Always the Same? A Protocol Analysis of Insight in Compound Remote Associate Problems

    Science.gov (United States)

    Cranford, Edward A.; Moss, Jarrod

    2012-01-01

    Compound Remote Associate (CRA) problems have been used to investigate insight problem solving using both behavioral and neuroimaging techniques. However, it is unclear to what extent CRA problems exhibit characteristics of insight such as impasses and restructuring. CRA problem-solving characteristics were examined in a study in which…

  17. IPE data base structure and insights

    International Nuclear Information System (INIS)

    Lehner, J.; Youngblood, R.

    1993-01-01

    A data base (the ''IPE Insights Data Base''), has been developed that stores data obtained from the Individual Plant Examinations (IPEs) which licensees of nuclear power plants are conducting in response to the Nuclear Regulatory Commission's (NRC) Generic Letter GL88-20. The data base, which is a collection of linked dbase files, stores information about individual plant designs, core damage frequency, and containment performance in a uniform, structured way. This data base can be queried and used as a computational tool to derive insights regarding the plants for which data is stored. This paper sets out the objectives of the IPE Insights Data Base, describes its structure and contents, illustrates sample queries, and discusses possible future uses

  18. IPE data base structure and insights

    International Nuclear Information System (INIS)

    Lehner, J.; Youngblood, R.

    1994-01-01

    A data base (the open-quotes IPE Insights Data Baseclose quotes), has been developed that stores data obtained from the Individual Plant Examinations (IPEs) which licensees of nuclear power plants are conducting in response to the Nuclear Regulatory Commission's (NRC) Generic Letter GL88-20. The data base, which is a collection of linked dBase files, stores information about individual plant designs, core damage frequency, and containment performance in a uniform, structured way. This data base can be queried and used as a computational tool to derive insights regarding the plants for which data is stored. This paper sets out the objectives of the IPE Insights Data Base, describes its structure and contents, illustrates sample queries, and discusses possible future uses

  19. Illness Insight and Recovery: How Important is Illness Insight in Peoples’ Recovery Process?

    DEFF Research Database (Denmark)

    Korsbek, Lisa

    2013-01-01

    . Sources Used:The writing is based on research literature related to illness insight and on personal recovery experiences.Conclusions and Implications for Practice: It is helpful to consider the integration of the issue of illness insight when addressing the questions and consequences of diagnosis......Topic: This account reflects on the topic of illness insight and recovery. Purpose: The purpose of the account is to clarify our understanding about the importance of illness insight in peoples’ recovery process, especially when relating the question of illness insight to the question of identity......, and to assist individuals to work through the false analogy between illness and identity while supporting the transformation from patient to person. It is also necessary for clinicians to develop a clear understanding of peoples’ actual needs and gain more knowledge about peoples’ own views and experiences...

  20. Human Performance on Insight Problem Solving: A Review

    Science.gov (United States)

    Chu, Yun; MacGregor, James N.

    2011-01-01

    The article provides a review of recent research on insight problem-solving performance. We discuss what insight problems are, the different types of classic and newer insight problems, and how we can classify them. We also explain some of the other aspects that affect insight performance, such as hints, analogs, training, thinking aloud, and…

  1. Insight, Cognitive Insight and Sociodemographic Features in Obsessive Compulsive Disorder Presenting with Reactive and Autogeneus Features

    Directory of Open Access Journals (Sweden)

    Katre ÇAMLI

    2012-03-01

    Full Text Available Objective: The aim of the present study was to test hypothesis that obsessive compulsive disorder (OCD patients who have autogenous obsessions and reactive obsessions show different sociodemographic and clinical characteristics with different insight and cognitive insight levels. Method: Sixty-one patients diagnosed as OCD according to the Structured Clinical Interview for DSM-III-R (SCID-I are recruited. 31 patients had reactive obsessions and 30 had autogenous obsessions. The sociodemographic characteristics of patients and the symptomatology were evaluated using psychiatric scales including SCID-I, Yale Brown Obsessive- Compulsive Scale (YBOCS, Yale Brown Obsessive-Compulsive Scale-Symptom Checklist (YBOCS-SC and Beck Insight Scale. Results: The percentage of women in reactive obsessive group was higher and also this group had significantly less antipsychotic medication prescribed than the autogenous obsessive group. No significant difference was found for the other demographic variables. No significant difference was identified for the Beck Insight Self-Reflectiveness subscale but for the Self-Certainty subscale, reactive obsessives had higher scores. Although there was no significant difference for the composit index points, which is the subtraction of the two subscales, the p value was close to the limit. On the other hand YBOCS item- 11 scores which evaluates insight were higher in autogenous obsessives meaning low levels of insight. Conclusion: For the sociodemographic and clinical characteristics; there was no significant difference between the groups except gender distribution and antipsychotic medication. Our data about insight seems inconsistent but insight and cognitive insight can be different entities which show different levels of insight. Further investigation with different obsession types is needed.

  2. Georgetown University Research Psychologist Shares Terrorism Insight

    OpenAIRE

    Center for Homeland Defense and Security

    2013-01-01

    Georgetown University research psychologist Dr. Anne Speckhard has spent the last decade interviewing more than four hundred terrorists, terrorist supporters, family members, close associates and even terrorist's hostages in Western Europe and the Middle East. Speckhard shared her insights with students at the Naval Postgraduate School Center for Homeland Defense and Security in July.

  3. Creativity and Insight in Problem Solving

    Science.gov (United States)

    Golnabi, Laura

    2016-01-01

    This paper analyzes the thought process involved in problem solving and its categorization as creative thinking as defined by psychologist R. Weisberg (2006). Additionally, the notion of insight, sometimes present in unconscious creative thinking and often leading to creative ideas, is discussed in the context of geometry problem solving. In…

  4. Some new insights into collimator design

    International Nuclear Information System (INIS)

    Metz, C.E.; Atkins, F.B.; Tsui, B.M.W.; Beck, R.N.

    1978-01-01

    Relationships among collimator design parameters, physical properties of the resulting images, and human observer performance are discussed. The insight provided by these relationships hopefully will prove useful to the individual who must design or select a collimator for a particular imaging task

  5. Gestures and Insight in Advanced Mathematical Thinking

    Science.gov (United States)

    Yoon, Caroline; Thomas, Michael O. J.; Dreyfus, Tommy

    2011-01-01

    What role do gestures play in advanced mathematical thinking? We argue that the role of gestures goes beyond merely communicating thought and supporting understanding--in some cases, gestures can help generate new mathematical insights. Gestures feature prominently in a case study of two participants working on a sequence of calculus activities.…

  6. Scientific Visualization: From Data to Insight

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 18; Issue 7. Scientific Visualization: From Data to Insight. Vijay Natarajan. General Article Volume 18 Issue 7 July 2013 pp 615-629. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/018/07/0615-0629 ...

  7. Innovative Leadership: Insights from a Learning Technologist

    Science.gov (United States)

    Campbell, Bruce

    2012-01-01

    Professor Ricardo Torres Kompen is a leading proponent for, and researcher in, personal learning environments (PLEs). During his interview, Torres Kompen clarified his research on PLEs, particularly the digital toolbox within PLEs. He elaborated on experiences with implementing PLE initiatives, personal insights on using social media and Web 2.0…

  8. Vitamin B12: advances and insights

    DEFF Research Database (Denmark)

    individuals in critical life phases. This book has been written by experts who documented latest developments in the field. It is written for individuals looking for in depth knowledge of the nutritional, chemistry, biochemistry, health and medical relevance of the vitamin. The book provides insights...

  9. Developmental Social Cognitive Neuroscience: Insights from Deafness

    Science.gov (United States)

    Corina, David; Singleton, Jenny

    2009-01-01

    The condition of deafness presents a developmental context that provides insight into the biological, cultural, and linguistic factors underlying the development of neural systems that impact social cognition. Studies of visual attention, behavioral regulation, language development, and face and human action perception are discussed. Visually…

  10. Innovate or perish: The RSM Insight debate

    OpenAIRE

    Gilbert, Russell

    2014-01-01

    markdownabstract__Abstract__ Although innovation is one the hottest management topics of the 21st century, very few firms excel at it. Here, in the first RSM Insight debate, three of the school’s leading management scholars discuss how firms should approach the subject of innovation and what it takes to be successful at it.

  11. Innovate or perish : The RSM Insight debate

    NARCIS (Netherlands)

    R. Gilbert (Russell)

    2014-01-01

    markdownabstract__Abstract__ Although innovation is one the hottest management topics of the 21st century, very few firms excel at it. Here, in the first RSM Insight debate, three of the school’s leading management scholars discuss how firms should approach the subject of innovation and what

  12. Insight in schizophrenia : Associations with empathy

    NARCIS (Netherlands)

    Pijnenborg, G. H. M.; Spikman, J. M.; Jeronimus, B. F.; Aleman, A.

    Many people with schizophrenia (50-80 %) demonstrate impaired insight, something which has been associated with a poorer outcome. Two types of empathy can be distinguished: affective empathy via shared emotions and cognitive empathy, also referred to as Theory of Mind (ToM). ToM can be subdivided

  13. Tour Guiding Research Insights, Issues and Implications

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt

    2017-01-01

    The book Tour guiding research – insights, issues and implications by Betty Weiler and Rosemary Black is a most welcome contribution to the specific research field of guided tours within tourism studies. It sets forth to “give an authoritative state-of-art review of the scholarly literature on tour...

  14. Insights and their emergence in everyday practices

    DEFF Research Database (Denmark)

    Trasmundi, Sarah Bro; Linell, Per

    2017-01-01

    of sense-making, problem-solving and task performance in naturalistic contexts. Second, it presents a promising method for the analysis of cognitive activities, Cognitive Event Analysis (CEA), with which we investigate real-life medical interactions, especially the emergence of insights in procedural task......-cultural patterns of behaviour....

  15. Safeguarding our environment: insight from an African ...

    African Journals Online (AJOL)

    The care and management of the natural environment constitutes an important aspect of environmental philosophy; an area of study that critically scrutinizes and evaluates human activities in his environment. African environmental ethics approaches problematic fundamental issues in deep ecology with a unique insight, ...

  16. Swahili residential architecture reconsidered | Steyn | Africa Insight

    African Journals Online (AJOL)

    Africa Insight. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 32, No 2 (2002) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT ...

  17. Insights on some chiral smectic phases

    Indian Academy of Sciences (India)

    journal of. August 2003 physics pp. 285–295. Insights on some chiral ... Liquid crystals; smectics; chirality; frustrated phases; twist grain boundary phases. ... molecules are more or less packed in layers and smectic phases can be seen ..... (imaging plate or CCD camera) which was located at about 300 mm from the sample.

  18. Cognitive Psychology--An Educational Insight

    Science.gov (United States)

    Muirhead, Brent

    2007-01-01

    Cognitive psychology offers relevant insights into improving the teaching and learning process. The author has selected ten questions from a graduate class in cognition and learning taken at The Teachers College, Columbia University. The questions will be used to examine the most effective ways to learn and recall information.

  19. The association of lifetime insight and cognition in psychosis.

    Science.gov (United States)

    Sánchez-Torres, Ana M; Zarzuela, Amalia; Peralta, Victor; Cuesta, Manuel J

    2015-03-01

    Poor insight has been related to poor course in psychosis. However, the role of cognition in insight remains unclear. The aim of this study was to examine the influence of cognition and lifetime psychopathological dimensions on insight in psychosis. We followed up 42 patients with psychotic disorders over 10years. Lifetime psychopathological dimensions and cognitive performance were assessed. Patients were divided into two groups by lifetime patterns of insight and compared with 42 healthy volunteers. Lower IQ and poorer social cognition were associated with higher risks of poorer lifetime insight of feeling ill and global insight respectively. Lifetime negative symptoms were associated with a higher risk of poorer lifetime insight into symptoms. Lifetime lack of insight is independent of cognitive impairment in specific domains, except for social cognition. Higher IQ may contribute to better lifetime awareness of illness, while better ability to manage emotions is involved in lifetime global insight. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Clinical correlates of loss of insight in bipolar depression

    Directory of Open Access Journals (Sweden)

    Rafael de Assis da Silva

    Full Text Available Abstract Introduction Affective state may influence insight, especially regarding mania. Nevertheless, studies have so far suggested that depression seems not to significantly impair insight. To the best of our knowledge, this study pioneers the evaluation of how insight variations in bipolar depression correlate with clinical variables. Method A group of 165 bipolar patients, 52 of whom had depressive episodes according to DSM-5 criteria, were followed during a year. All patients underwent clinical assessment, and insight was evaluated through the Insight Scale for Affective Disorders (ISAD. Repeated-measures ANOVA was calculated comparing scores on the four ISAD factors (insight into symptoms, the condition itself, self-esteem and social relationships in order to investigate differences in insight according to different objects. Correlational analysis explored which clinical symptoms were linked to reduced insight. Results Worse total insight correlated with suicide attempt/ideation and fewer subsyndromal manic symptoms such as mood elevation, increased energy and sexual interest. Worse self-esteem insight was associated with not only suicide ideation/attempt but also with activity reduction and psychomotor retardation. Worse symptom insight also correlated with psychomotor retardation. Better insight into having an affective disorder was associated with more intense hypochondria symptoms. Finally, worse insight into having an illness was associated with psychotic episodes. Conclusion Our study found that symptoms other than psychosis – suicide ideation, psychomotor retardation and reduction of activity and work – correlate with insight impairment in bipolar depression.

  1. The "Insight Paradox" in Schizophrenia: Magnitude, Moderators and Mediators of the Association Between Insight and Depression.

    Science.gov (United States)

    Belvederi Murri, Martino; Amore, Mario; Calcagno, Pietro; Respino, Matteo; Marozzi, Valentina; Masotti, Mattia; Bugliani, Michele; Innamorati, Marco; Pompili, Maurizio; Galderisi, Silvana; Maj, Mario

    2016-09-01

    The so-called "insight paradox" posits that among patients with schizophrenia higher levels of insight are associated with increased levels of depression. Although different studies examined this issue, only few took in account potential confounders or factors that could influence this association. In a sample of clinically stable patients with schizophrenia, insight and depression were evaluated using the Scale to assess Unawareness of Mental Disorder and the Calgary Depression Scale for Schizophrenia. Other rating scales were used to assess the severity of psychotic symptoms, extrapyramidal symptoms, hopelessness, internalized stigma, self-esteem, and service engagement. Regression models were used to estimate the magnitude of the association between insight and depression while accounting for the role of confounders. Putative psychological and sociodemographic factors that could act as mediators and moderators were examined using the PROCESS macro. By accounting for the role of confounding factors, the strength of the association between insight into symptoms and depression increased from 13% to 25% explained covariance. Patients with lower socioeconomic status (F = 8.5, P = .04), more severe illness (F = 4.8, P = .03) and lower levels of service engagement (F = 4.7, P = .03) displayed the strongest association between insight and depression. Lastly, hopelessness, internalized stigma and perceived discrimination acted as significant mediators. The relationship between insight and depression should be considered a well established phenomenon among patients with schizophrenia: it seems stronger than previously reported especially among patients with lower socioeconomic status, severe illness and poor engagement with services. These findings may have relevant implications for the promotion of insight among patients with schizophrenia. © The Author 2016. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved

  2. Insights from Human/Mouse genome comparisons

    Energy Technology Data Exchange (ETDEWEB)

    Pennacchio, Len A.

    2003-03-30

    Large-scale public genomic sequencing efforts have provided a wealth of vertebrate sequence data poised to provide insights into mammalian biology. These include deep genomic sequence coverage of human, mouse, rat, zebrafish, and two pufferfish (Fugu rubripes and Tetraodon nigroviridis) (Aparicio et al. 2002; Lander et al. 2001; Venter et al. 2001; Waterston et al. 2002). In addition, a high-priority has been placed on determining the genomic sequence of chimpanzee, dog, cow, frog, and chicken (Boguski 2002). While only recently available, whole genome sequence data have provided the unique opportunity to globally compare complete genome contents. Furthermore, the shared evolutionary ancestry of vertebrate species has allowed the development of comparative genomic approaches to identify ancient conserved sequences with functionality. Accordingly, this review focuses on the initial comparison of available mammalian genomes and describes various insights derived from such analysis.

  3. Safety insights from forensics evaluations at Daiichi

    Directory of Open Access Journals (Sweden)

    J. Rempe

    2017-01-01

    Information obtained from Daiichi is required to inform Decontamination and Decommissioning activities, improving the ability of the Tokyo Electric Power Company (TEPCO to characterize potential hazards and to ensure the safety of workers involved with cleanup activities. This paper reports initial results from the US Forensics Effort to utilize examination information obtained by TEPCO to enhance the safety of existing and future nuclear power plant designs. In this paper, three examples are presented in which examination information, such as visual images, dose surveys, sample evaluations, and muon tomography examinations, along with data from plant instrumentation, are used to obtain significant safety insights in the areas of component performance, fission product release and transport, debris end-state location, and combustible gas generation and transport. In addition to reducing uncertainties related to severe accident modeling progression, these insights confirm actions, such as the importance of water addition and containment venting, that are emphasized in updated guidance for severe accident prevention, mitigation, and emergency planning.

  4. Forming a Perceived Franchise Value: Theoretical Insights

    OpenAIRE

    Levickaitė, Rasa; Reimeris, Ramojus

    2011-01-01

    The article is based on literature review, theoretical insights and deals with the topic of perceived franchise value. The objective of the paper is – what elements form the franchisee's perceived value in service business (comparing with alternative of own business model). The aim of the paper is to propose systematic value elements in the process of forming a value of a franchise business model perceived by the franchisee. In terms of practical meaning, this article should be relevant to en...

  5. Biblical Leadership: Insights for Today's Managers

    OpenAIRE

    Friedman, Hershey H.; Friedman, Linda

    2004-01-01

    The scholarly literature in management has paid little attention to the study of Biblical figures as leaders. This paper aims to advance the effort to fill this gap by demonstrating that many insights about successful and unsuccessful leadership may be derived from the Bible. Successful leaders demonstrated a willingness to be different, a passion for justice, humility, and a concern for others. Unsuccessful leaders were sidetracked from their mission by the hunger for power or by lust and envy.

  6. Paris after Trump: An Inconvenient Insight

    OpenAIRE

    Böhringer, Christoph; Rutherford, Thomas F.

    2017-01-01

    With his announcement to pull the US out of the Paris Agreement US President Donald Trump has snubbed the international climate policy community. Key remaining parties to the Agreement such as Europe and China might call for carbon tariffs on US imports as a sanctioning instrument to coerce US compliance. Our analysis, however, reveals an inconvenient insight for advocates of carbon tariffs: given the possibility of retaliatory tariffs across all imported goods, carbon tariffs do not constitu...

  7. Exploring Insight: Focus on Shifts of Attention

    Science.gov (United States)

    Palatnik, Alik; Koichu, Boris

    2015-01-01

    The paper presents and analyses a sequence of events that preceded an insight solution to a challenging problem in the context of numerical sequences. A three­week long solution process by a pair of ninth­-grade students is analysed by means of the theory of shifts of attention. The goal for this article is to reveal the potential of this theory…

  8. Egypt: Pharoahs and Fundamentalists? | Swart | Africa Insight

    African Journals Online (AJOL)

    Gerrie Swart, Hussein Solomon, Anneli Botha. Abstract. Africa Insight Vol.33(4) 2003: 78-81. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/ai.v33i4.22345 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  9. The Association of Insight and Change in Insight with Clinical Symptoms in Depressed Inpatients.

    Science.gov (United States)

    He, Hongbo; Chang, Qing; Ma, Yarong

    2018-04-25

    Lack of insight has been extensively studied and was found to be adversely correlated with impaired treatment compliance and worse long term clinical outcomes among patients with schizophrenia, while not much is known about this phenonmenon in patients with severe depression. To explore the correlates of insight and its relation to symptom changes among the most seriously ill patients with affective disorders, those who require hospitalization. Patients hospitalized in a large psychiatric hospital in south China with either major depressive disorder (MDD)(N=55) or bipolar depression (BD) (N=85) based on ICD-10 diagnostic criteria were assessed with the Insight and Treatment Attitudes Questionnaire (ITAQ) one week after admission and at the time of discharge. Clinical symptoms were measured at the same time with the Hamilton Rating Scale for Depression (HAMD-17) and the Depression subscale of the Symptom Check list-90 (SCL-90). Length of stay (LOS), duration of illness, duration of untreated mood disorder, number of previous episodes of depression and previous admissions for depression were documented during interviews with patients and their families and from a review of medical records. Bivariate correlations and multiple regression analysis were used to examine the relationship of sociodemographic characteristics, clinical symptomatology and clinical history, to insight at the time of admission. The relationships between change in clinical symptoms and change in insight from admission to discharge were also examined. Stepwise multiple regression models suggested that any previous admissions for depression and higher anxiety factor scores on the HAMD-17 are significant independent predictors of insight accounting for 22.9% of the variance. Multiple regression analysis residual change scores (change scores adjusted for baseline values) on the ITAQ showed that improved insight over average stays of 51 days were inversely related to the residual psychomotor

  10. Insightful problem solving in an Asian elephant.

    Directory of Open Access Journals (Sweden)

    Preston Foerder

    Full Text Available The "aha" moment or the sudden arrival of the solution to a problem is a common human experience. Spontaneous problem solving without evident trial and error behavior in humans and other animals has been referred to as insight. Surprisingly, elephants, thought to be highly intelligent, have failed to exhibit insightful problem solving in previous cognitive studies. We tested whether three Asian elephants (Elephas maximus would use sticks or other objects to obtain food items placed out-of-reach and overhead. Without prior trial and error behavior, a 7-year-old male Asian elephant showed spontaneous problem solving by moving a large plastic cube, on which he then stood, to acquire the food. In further testing he showed behavioral flexibility, using this technique to reach other items and retrieving the cube from various locations to use as a tool to acquire food. In the cube's absence, he generalized this tool utilization technique to other objects and, when given smaller objects, stacked them in an attempt to reach the food. The elephant's overall behavior was consistent with the definition of insightful problem solving. Previous failures to demonstrate this ability in elephants may have resulted not from a lack of cognitive ability but from the presentation of tasks requiring trunk-held sticks as potential tools, thereby interfering with the trunk's use as a sensory organ to locate the targeted food.

  11. Risk insights from seismic margin reviews

    International Nuclear Information System (INIS)

    Budnitz, R.J.

    1990-01-01

    This paper discusses the information that has been derived from the three seismic-margin reviews conducted so far, and the information that is potentially available from using the seismic-margin method more generally. There are two different methodologies for conducting seismic margin reviews of nuclear power plants, one developed under NRC sponsorship and one developed under sponsorship of the Electric Power Research Institute. Both methodologies will be covered in this paper. The paper begins with a summary of the steps necessary to complete a margin review, and will then outline the key technical difficulties that need to be addressed. After this introduction, the paper covers the safety and operational insights derived from the three seismic-margin reviews already completed: the NRC-sponsored review at Maine Yankee; the EPRI-sponsored review at Catawba; and the joint EPRI/NRC/utility effort at Hatch. The emphasis is on engineering insights, with attention to the aspects of the reviews that are easiest to perform and that provide the most readily available insights

  12. 2016 Mars Insight Mission Design and Navigation

    Science.gov (United States)

    Abilleira, Fernando; Frauenholz, Ray; Fujii, Ken; Wallace, Mark; You, Tung-Han

    2014-01-01

    Scheduled for a launch in the 2016 Earth to Mars opportunity, the Interior Exploration using Seismic Investigations, Geodesy, and Heat Transport (InSight) Mission will arrive to Mars in late September 2016 with the primary objective of placing a science lander on the surface of the Red Planet followed by the deployment of two science instruments to investigate the fundamental processes of terrestrial planet formation and evolution. In order to achieve a successful landing, the InSight Project has selected a launch/arrival strategy that satisfies the following key and driving requirements: (1) Deliver a total launch mass of 727 kg, (2) target a nominal landing site with a cumulative Delta V99 less than 30 m/s, and (3) approach EDL with a V-infinity upper limit of 3.941 km/s and (4) an entry flight-path angle (EFPA) of -12.5 +/- 0.26 deg, 3-sigma; the InSight trajectories have been designed such that they (5) provide UHF-band communications via Direct-To-Earth and MRO from Entry through landing plus 60 s, (6) with injection aimpoints biased away from Mars such that the probability of the launch vehicle upper stage impacting Mars is less than 1.0 X 10(exp 4) for fifty years after launch, and (7) non-nominal impact probabilities due to failure during the Cruise phase less than 1.0 X 10(exp 2).

  13. Insights from an overview of four PRAs

    International Nuclear Information System (INIS)

    Fitzpatrick, R.; Arrieta, L.; Teichmann, T.; Davis, P.

    1987-01-01

    This paper summarizes the findings of an investigation of four probabilistic risk assessments (PRAs), those for Millstone 3 Seabrook, Shoreham, and Oconee 3, performed by Brookhaven National Laboratory (BNL) for the Reliability and Risk Assessment branch of the U.S. Nuclear Regulatory Commission (NRC). This group of four PRAs was subjected to an overview process with the basic goal of ascertaining what insights might be gained (beyond those already documented within the individual PRAs) by an independent evaluation of the group with respect to nuclear plant safety and vulnerability. Specifically, the objectives of the study were 1) to identify and rank initiators, systems, components, and failure modes from dominant accident sequences according to their contribution to core melt probability and public risk; and 2) to derive from this process plant-specific and generic insights. The effort was not intended to verify the specific details and results of each PRA but rather - having accepted the results - to see what they might mean in a more global context. This paper also presents some comments and insights into the amenability of certain features of these PRAs to this type of overview process

  14. Insightful problem solving in an Asian elephant.

    Science.gov (United States)

    Foerder, Preston; Galloway, Marie; Barthel, Tony; Moore, Donald E; Reiss, Diana

    2011-01-01

    The "aha" moment or the sudden arrival of the solution to a problem is a common human experience. Spontaneous problem solving without evident trial and error behavior in humans and other animals has been referred to as insight. Surprisingly, elephants, thought to be highly intelligent, have failed to exhibit insightful problem solving in previous cognitive studies. We tested whether three Asian elephants (Elephas maximus) would use sticks or other objects to obtain food items placed out-of-reach and overhead. Without prior trial and error behavior, a 7-year-old male Asian elephant showed spontaneous problem solving by moving a large plastic cube, on which he then stood, to acquire the food. In further testing he showed behavioral flexibility, using this technique to reach other items and retrieving the cube from various locations to use as a tool to acquire food. In the cube's absence, he generalized this tool utilization technique to other objects and, when given smaller objects, stacked them in an attempt to reach the food. The elephant's overall behavior was consistent with the definition of insightful problem solving. Previous failures to demonstrate this ability in elephants may have resulted not from a lack of cognitive ability but from the presentation of tasks requiring trunk-held sticks as potential tools, thereby interfering with the trunk's use as a sensory organ to locate the targeted food.

  15. The relationship between insight and psychosis in state patients with ...

    African Journals Online (AJOL)

    Objective. State patients committed under the Mental Health Act must have insight into their illness and the crime they committed before they can be discharged. Patients with schizophrenia are described as having poor insight into the nature and severity of their disorder. Various factors influence insight, and in some studies ...

  16. Hydrogeology of Montserrat review and new insights

    Directory of Open Access Journals (Sweden)

    Brioch Hemmings

    2015-03-01

    Full Text Available Study region: The tropical, active volcanic arc island of Montserrat, Lesser Antilles, Caribbean. Study focus: New insights into hydrological recharge distribution, measurements of aquifer permeability, and geological and hydrological field observations from Montserrat are combined with a review of the current understanding of volcanic island hydrology. The aim is to begin to develop a conceptual model for the hydrology of Montserrat, and to inform and stimulate further investigation into the hydrology of volcanic arc islands, by combining a review of the current understanding of essential components of the hydrological system with fresh analysis of existing data, and new observations, data collection and analysis. This study provides new insights into hydrological recharge distribution, measurements of aquifer permeability, and geological and hydrological field observations from Montserrat. New hydrological insights for the region: A new groundwater recharge model predicts whole island recharge of 266 mm/year, between 10% and 20% of annual rainfall. Core scale permeability tests reveal ranges from 10−14 to 10−12 m2 for volcaniclastic rocks with coarse matrix, to a minimum of 10−18 m2 for andesitic lavas and volcaniclastics with fine or altered matrix. Analysis of historical pumping tests on aquifers in reworked, channel and alluvial sediment indicate permeabilities ∼10−10 m2. Springs at elevations between 200 and 400 m above mean sea level on Centre Hills currently discharge over 45 L/s. High discharge require a reasonably laterally continuous low permeability body. Contrasting conceptual models are presented to illustrate two potential hydrogeological scenarios. New field observations also reveal systematic spatial variations in spring water temperature and specific electrical conductivity indicating that meteoric waters supplying the springs are mixed with a deeper groundwater source at some sites. Keywords: Volcanic island

  17. Third-person Diagnostic Interview on the Cognitive Insight Level of Psychotic Patients with an Insight at the Denial Level.

    Science.gov (United States)

    Mehdizadeh, Mahsa; Rezaei, Omid

    2016-01-01

    According to the previous findings, the third-person technique improved the clinical insight of psychotic patients, therefore the present study aims to examine the effect of a third-person interview compared to a first-person interview on the level of cognitive insight of psychotic patients with an insight at the denial level. In this study, using interviews and questionnaires, a total number of 44 patients of Razi Psychiatric Educational and Treatment Center with an insight at the denial level being assessed using diagnostic interviews were divided randomly into two groups. Then, the two groups of patients' cognitive insights were evaluated using Beck Cognitive Insight Scale. The findings indicated that in psychotic patients with an insight at the denial level, the third-person technique of interview compared to the first-person had little effect on the improvement of overall cognitive insight and its components, including self-reflection and self-assurance; however, this effect was not strong enough to make a significant difference between the two groups of patients. According to the study findings, we can conclude that the third-person interview compared to the first-person interview has no effect on the improvement of the cognitive insight of psychotic patients with an insight at the denial level. This finding is consistent with the previous studies indicating that although the theory of mind has some correlations with the clinical insight of patients, it has no effect on their cognitive insight.

  18. Is Humanity Doomed? Insights from Astrobiology

    Directory of Open Access Journals (Sweden)

    Seth D. Baum

    2010-02-01

    Full Text Available Astrobiology, the study of life in the universe, offers profound insights into human sustainability. However, astrobiology is commonly neglected in sustainability research. This paper develops three topics connecting astrobiology to sustainability: constraints on what zones in the universe are habitable, the absence of observations of extraterrestrial civilizations, and the physical fate of the universe. These topics have major implications for our thinking and action on sustainability. While we may not be doomed, we must take certain actions to sustain ourselves in this universe. The topics also suggest that our current sustainability efforts may be of literally galactic importance.

  19. A Storytelling Approach: Insights from the Shambaa.

    Science.gov (United States)

    Lamanna, Camillo

    2018-03-19

    Narrative medicine explores the stories that patients tell; this paper, conversely, looks at some of the stories that patients are told. The paper starts by examining the 'story' told by the Shambaa people of Tanzania to explain the bubonic plague and contrasts this with the stories told by Ghanaian communities to explain lymphatic filariasis. By harnessing insights from memory studies, these stories' memorability is claimed to be due to their use mnemonic devices woven into stories. The paper suggests that stories can be unpatronising, informative, and appropriate vehicles for communicating medical information to all age groups across all cultures.

  20. Stigma as a predictor of insight in schizophrenia.

    Science.gov (United States)

    Pruß, Linda; Wiedl, Karl Heinz; Waldorf, Manuel

    2012-07-30

    Insight in schizophrenia can be seen as a multifactorial phenomenon. Although multifactorial pathways have also been suggested for insight formation, motivational explanations have rarely been tested. The present study explores stigma as one possible determinant of a motivated lack of insight in integrated models of insight formation. It examines the contribution of socio-demographic and clinical variables, neurocognitive functions, symptoms, and stigma to the prediction of insight into illness. Patients diagnosed with schizophrenia spectrum disorders (N=111) participated in a comprehensive battery of instruments to measure insight dimensions, stigma, neurocognitive functions, symptoms, socio-demographic and clinical variables. Blockwise multiple regression analysis indicates significant association of variability in insight dimensions with gender (7%) and stigma (i. e., stereotype agreement: 5%). Our findings demonstrate an incremental validity of stigma, which indicates a motivational pathway of insight formation. This study enables better understanding of the multifactorial nature of insight, which should be considered in therapeutic interventions to improve insight. The roles of gender and neurocognitive functions in insight formation are also discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Risk Insights Gained from Fire Incidents

    International Nuclear Information System (INIS)

    Kazarians, Mardy; Nowlen, Steven P.

    1999-01-01

    There now exist close to 20 years of history in the application of Probabilistic Risk Assessment (PRA) for the analysis of fire risk at nuclear power plants. The current methods are based on various assumptions regarding fire phenomena, the impact of fire on equipment and operator response, and the overall progression of a fire event from initiation through final resolution. Over this same time period, a number of significant fire incidents have occurred at nuclear power plants around the world. Insights gained from US experience have been used in US studies as the statistical basis for establishing fire initiation frequencies both as a function of the plant area and the initiating fire source.To a lesser extent, the fire experience has also been used to assess the general severity and duration of fires. However, aside from these statistical analyses, the incidents have rarely been scrutinized in detail to verify the underlying assumptions of fire PRAs. This paper discusses an effort, under which a set of fire incidents are being reviewed in order to gain insights directly relevant to the methods, data, and assumptions that form the basis for current fire PRAs. The paper focuses on the objectives of the effort, the specific fire events being reviews methodology, and anticipated follow-on activities

  2. Insights to regenerate materials: learning from nature

    Science.gov (United States)

    García-Aznar, J. M.; Valero, C.; Gómez-Benito, M. J.; Javierre, E.

    2016-08-01

    Self-healing materials, both biological and engineered, integrate the ability to repair themselves and recover their functionality using the resources inherently available to them. Although significant advances have been made, in recent years, for the design of different concepts of self-healing materials, this work aims to provide some insights into how living materials are able to regenerate or heal when a fracture or injury occurs. The main sensors that regulate this adaptive and regenerative behavior are the cells. These are able to sense the mechanical alterations in their surroundings and regulate their activity in order to remove dead tissue and/or create new tissue. Therefore, understanding how cells are able to regenerate tissues under complex and multiphysics conditions can define the biomimetics guidelines to heal through inert or traditional engineering materials. In this work, we present a combination of experiments and different kinds of multiscale and multiphysics models in order to understand how mechanics regulate some mechanisms at cell and tissue level. This combination of results aims to gain insight into the development of novel strategies for self-healing materials, mimicking the behavior induced by cells and biological tissues.

  3. Avian Incubation Patterns Reflect Temporal Changes in Developing Clutches.

    Directory of Open Access Journals (Sweden)

    Caren B Cooper

    Full Text Available Incubation conditions for eggs influence offspring quality and reproductive success. One way in which parents regulate brooding conditions is by balancing the thermal requirements of embryos with time spent away from the nest for self-maintenance. Age related changes in embryo thermal tolerance would thus be expected to shape parental incubation behavior. We use data from unmanipulated Black-capped Chickadee (Poecile atricapillus nests to examine the temporal dynamics of incubation, testing the prediction that increased heat flux from eggs as embryos age influences female incubation behavior and/or physiology to minimize temperature fluctuations. We found that the rate of heat loss from eggs increased with embryo age. Females responded to increased egg cooling rates by altering incubation rhythms (more frequent, shorter on- and off- bouts, but not brood patch temperature. Consequently, as embryos aged, females were able to increase mean egg temperature and decrease variation in temperature. Our findings highlight the need to view full incubation as more than a static rhythm; rather, it is a temporally dynamic and finely adjustable parental behavior. Furthermore, from a methodological perspective, intra- and inter-specific comparisons of incubation rhythms and average egg temperatures should control for the stage of incubation.

  4. Carotenoid-based breast plumage colour, body condition and clutch ...

    African Journals Online (AJOL)

    dependent ornamental trait. In some species of birds, red, orange and yellow feather colouration reflects male quality and advertises the carotenoid concentration of feathers. Such colouration is an important aspect of mate selection by females.

  5. Brood parasites lay eggs matching the appearance of host clutches

    Czech Academy of Sciences Publication Activity Database

    Honza, Marcel; Šulc, Michal; Jelínek, Václav; Požgayová, Milica; Procházka, Petr

    2014-01-01

    Roč. 281, č. 1774 (2014), s. 20132665 ISSN 0962-8452 R&D Projects: GA AV ČR IAA600930903; GA ČR(CZ) GAP506/12/2404 Institutional support: RVO:68081766 Keywords : brood parasitism * cuckoo * egg coloration * egg mimicry * great reed warbler Subject RIV: EG - Zoology Impact factor: 5.051, year: 2014

  6. AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT I, UNDERSTANDING MECHANICAL CLUTCHES.

    Science.gov (United States)

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    ONE OF A 25-MODULE COURSE DESIGNED TO UPGRADE THE JOB SKILLS AND TECHNICAL KNOWLEDGE OF DIESEL MAINENANCE MECHANICS THIS MATERIAL WAS DEVELOPED BY INDUSTRIAL TRAINING AND SUBJECT-MATTER SPECIALISTS AND TESTED IN INDUSTRIAL TRAINING SITUATIONS. THE PURPOSE OF THIS FIRST UNIT IS TO DEVELOP AN UNDERSTANDING OF COMPONENTS, OPERATION, AND ADJUSTMENTS…

  7. New insights into insight: Neurophysiological correlates of the difference between the intrinsic "aha" and the extrinsic "oh yes" moment.

    Science.gov (United States)

    Rothmaler, Katrin; Nigbur, Roland; Ivanova, Galina

    2017-01-27

    Insight refers to a situation in which a problem solver immediately changes his understanding of a problem situation. This representational change can either be triggered by external stimuli, like a hint or the solution itself, or by internal solution attempts. In the present paper, the differences and similarities between these two phenomena, namely "extrinsic" and "intrinsic" insight, are examined. To this end, electroencephalogram (EEG) is recorded while subjects either recognize or generate solutions to German verbal compound remote associate problems (CRA). Based on previous studies, we compare the alpha power prior to insightful solution recognition with the alpha power prior to insightful solution generation. Results show that intrinsic insights are preceded by an increase in alpha power at right parietal electrodes, while extrinsic insights are preceded by a respective decrease. These results can be interpreted in two ways. In consistency with other studies, the increase in alpha power before intrinsic insights can be interpreted as an increased internal focus of attention. Accordingly, the decrease in alpha power before extrinsic insights may be associated with a more externally oriented focus of attention. Alternatively, the increase in alpha power prior to intrinsic insights can be interpreted as an active inhibition of solution-related information, while the alpha power decrease prior to extrinsic insights may reflect its activation. Regardless of the interpretation, the results provide strong evidence that extrinsic and intrinsic insight differ on the behavioral as well as the neurophysiological level. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Neurobiological Basis of Insight in Schizophrenia: A Systematic Review.

    Science.gov (United States)

    Xavier, Rose Mary; Vorderstrasse, Allison

    2016-01-01

    Insight in schizophrenia is defined as awareness into illness, symptoms, and need for treatment and has long been associated with cognition, other psychopathological symptoms, and several adverse clinical and functional outcomes. However, the biological basis of insight is not clearly understood. The aim of this systematic review was to critically evaluate and summarize advances in the study of the biological basis of insight in schizophrenia and to identify gaps in this knowledge. A literature search of PubMed, CINAHL, PsycINFO, and EMBASE databases was conducted using search terms to identify articles relevant to the biology of insight in schizophrenia published in the last 6 years. Articles that focused on etiology of insight in schizophrenia and those that examined the neurobiology of insight in schizophrenia or psychoses were chosen for analysis. Articles on insight in conditions other than schizophrenia or psychoses and which did not investigate the neurobiological underpinnings of insight were excluded from the review. Twenty-six articles met the inclusion criteria for this review. Of the 26 articles, 3 focused on cellular abnormalities and 23 were neuroimaging studies. Preliminary data identify the prefrontal cortex, cingulate cortex, and regions of the temporal and parietal lobe (precuneus, inferior parietal lobule) and hippocampus as the neural correlates of insight. A growing body of literature attests to the neurobiological basis of insight in schizophrenia. Current evidence supports the neurobiological basis of insight in schizophrenia and identifies specific neural correlates for insight types and its dimensions. Further studies that examine the precise biological mechanisms of insight are needed to apply this knowledge to effective clinical intervention development.

  9. Operating experience insights supporting ageing assessments

    International Nuclear Information System (INIS)

    Nitoi, M.

    2013-01-01

    Be effective in ageing management means looking at the right aspects, with the right techniques, and one of the most effective tool which could be used for that purpose is the analysis of operating experience. The paper has as objective to perform a review of available operating experience, with the aim to provide a better picture about the impact of ageing effects. The IAEA International Reporting System and NRC Licensee Event Reports were chosen as reference databases, both databases being internationally recognized as important sources of information about events occurrences in the nuclear power plants. The ageing related events identified in the selected time window were analyzed in detail, and the contributions of each major degradation mechanisms that have induced the ageing related events (specific to each defined group of components) was represented and discussed. The paper demonstrates the possibility to use operating experience insights in highlighting the ageing effects. (authors)

  10. Structural insights into microtubule doublet interactions inaxonemes

    Energy Technology Data Exchange (ETDEWEB)

    Downing, Kenneth H.; Sui, Haixin

    2007-06-06

    Coordinated sliding of microtubule doublets, driven by dynein motors, produces periodic beating of the axoneme. Recent structural studies of the axoneme have used cryo-electron tomography to reveal new details of the interactions among some of the multitude of proteins that form the axoneme and regulate its movement. Connections among the several sets of dyneins, in particular, suggest ways in which their actions may be coordinated. Study of the molecular architecture of isolated doublets has provided a structural basis for understanding the doublet's mechanical properties that are related to the bending of the axoneme, and has also offered insight into its potential role in the mechanism of dynein activity regulation.

  11. Phylogeographic insights into cryptic glacial refugia.

    Science.gov (United States)

    Provan, Jim; Bennett, K D

    2008-10-01

    The glacial episodes of the Quaternary (2.6 million years ago-present) were a major factor in shaping the present-day distributions of extant flora and fauna, with expansions and contractions of the ice sheets rendering large areas uninhabitable for most species. Fossil records suggest that many species survived glacial maxima by retreating to refugia, usually at lower latitudes. Recently, phylogeographic studies have given support to the existence of previously unknown, or cryptic, refugia. Here we summarise many of these insights into the glacial histories of species in cryptic refugia gained through phylogeographic approaches. Understanding such refugia might be important as the Earth heads into another period of climate change, in terms of predicting the effects on species distribution and survival.

  12. New insights regarding ATWS for BWRS

    International Nuclear Information System (INIS)

    Drouin, M.T.; Kolaczkowski, A.M.; LaChance, J.L.; Ferrell, W.L.

    1987-01-01

    Anticipated transients without scram (ATWS) accident sequences have been found in past studies to have a relatively high core damage frequency (ranging from 5.4E-6 to 3E-4 per year) that represents a significant contribution to the total core damage frequency (ranging from 7-to-33%). Results of analyses for the two boiling water reactors (BWRs) analyzed as part of NUREG/CR-4550 indicate both a lower core damage frequency (ranging from 2E-7 to 1E-6 per year) and a lower contribution to the total core damage frequency (ranging from <1-to-10%). Based on these updated analyses, newer insights on the effects of reactor power equilibration, recirculation pump trip, high and low pressure injection and high pressure seal failure coupled with a detailed accident sequence analysis have resulted in lowering the significance of ATWS to core damage frequency

  13. Insights into Mechanisms of Chronic Neurodegeneration

    Directory of Open Access Journals (Sweden)

    Abigail B. Diack

    2016-01-01

    Full Text Available Chronic neurodegenerative diseases such as Alzheimer’s disease (AD, Parkinson’s disease (PD, and prion diseases are characterised by the accumulation of abnormal conformers of a host encoded protein in the central nervous system. The process leading to neurodegeneration is still poorly defined and thus development of early intervention strategies is challenging. Unique amongst these diseases are Transmissible Spongiform Encephalopathies (TSEs or prion diseases, which have the ability to transmit between individuals. The infectious nature of these diseases has permitted in vivo and in vitro modelling of the time course of the disease process in a highly reproducible manner, thus early events can be defined. Recent evidence has demonstrated that the cell-to-cell spread of protein aggregates by a “prion-like mechanism” is common among the protein misfolding diseases. Thus, the TSE models may provide insights into disease mechanisms and testable hypotheses for disease intervention, applicable to a number of these chronic neurodegenerative diseases.

  14. Anthelmintic metabolism in parasitic helminths: proteomic insights.

    Science.gov (United States)

    Brophy, Peter M; MacKintosh, Neil; Morphew, Russell M

    2012-08-01

    Anthelmintics are the cornerstone of parasitic helminth control. Surprisingly, understanding of the biochemical pathways used by parasitic helminths to detoxify anthelmintics is fragmented, despite the increasing global threat of anthelmintic resistance within the ruminant and equine industries. Reductionist biochemistry has likely over-estimated the enzymatic role of glutathione transferases in anthelmintic metabolism and neglected the potential role of the cytochrome P-450 superfamily (CYPs). Proteomic technologies offers the opportunity to support genomics, reverse genetics and pharmacokinetics, and provide an integrated insight into both the cellular mechanisms underpinning response to anthelmintics and also the identification of biomarker panels for monitoring the development of anthelmintic resistance. To date, there have been limited attempts to include proteomics in anthelmintic metabolism studies. Optimisations of membrane, post-translational modification and interaction proteomic technologies in helminths are needed to especially study Phase I CYPs and Phase III ABC transporter pumps for anthelmintics and their metabolites.

  15. Insights into software development in Japan

    Science.gov (United States)

    Duvall, Lorraine M.

    1992-01-01

    The interdependence of the U.S.-Japanese economies makes it imperative that we in the United States understand how business and technology developments take place in Japan. We can gain insight into these developments in software engineering by studying the context in which Japanese software is developed, the practices that are used, the problems encountered, the setting surrounding these problems, and the resolution of these problems. Context includes the technological and sociological characteristics of the software development environment, the software processes applied, personnel involved in the development process, and the corporate and social culture surrounding the development. Presented in this paper is a summary of results of a study that addresses these issues. Data for this study was collected during a three month visit to Japan where the author interviewed 20 software managers representing nine companies involved in developing software in Japan. These data are compared to similar data from the United States in which 12 managers from five companies were interviewed.

  16. Imaging morphogenesis: technological advances and biological insights.

    Science.gov (United States)

    Keller, Philipp J

    2013-06-07

    Morphogenesis, the development of the shape of an organism, is a dynamic process on a multitude of scales, from fast subcellular rearrangements and cell movements to slow structural changes at the whole-organism level. Live-imaging approaches based on light microscopy reveal the intricate dynamics of this process and are thus indispensable for investigating the underlying mechanisms. This Review discusses emerging imaging techniques that can record morphogenesis at temporal scales from seconds to days and at spatial scales from hundreds of nanometers to several millimeters. To unlock their full potential, these methods need to be matched with new computational approaches and physical models that help convert highly complex image data sets into biological insights.

  17. Insights from simulations of star formation

    International Nuclear Information System (INIS)

    Larson, Richard B

    2007-01-01

    Although the basic physics of star formation is classical, numerical simulations have yielded essential insights into how stars form. They show that star formation is a highly nonuniform runaway process characterized by the emergence of nearly singular peaks in density, followed by the accretional growth of embryo stars that form at these density peaks. Circumstellar discs often form from the gas being accreted by the forming stars, and accretion from these discs may be episodic, driven by gravitational instabilities or by protostellar interactions. Star-forming clouds typically develop filamentary structures, which may, along with the thermal physics, play an important role in the origin of stellar masses because of the sensitivity of filament fragmentation to temperature variations. Simulations of the formation of star clusters show that the most massive stars form by continuing accretion in the dense cluster cores, and this again is a runaway process that couples star formation and cluster formation. Star-forming clouds also tend to develop hierarchical structures, and smaller groups of forming objects tend to merge into progressively larger ones, a generic feature of self-gravitating systems that is common to star formation and galaxy formation. Because of the large range of scales and the complex dynamics involved, analytic models cannot adequately describe many aspects of star formation, and detailed numerical simulations are needed to advance our understanding of the subject. 'The purpose of computing is insight, not numbers.' Richard W Hamming, in Numerical Methods for Scientists and Engineers (1962) 'There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy.' William Shakespeare, in Hamlet, Prince of Denmark (1604) (key issues review)

  18. Insights from simulations of star formation

    Energy Technology Data Exchange (ETDEWEB)

    Larson, Richard B [Department of Astronomy, Yale University, Box 208101, New Haven, CT 06520-8101 (United States)

    2007-03-15

    Although the basic physics of star formation is classical, numerical simulations have yielded essential insights into how stars form. They show that star formation is a highly nonuniform runaway process characterized by the emergence of nearly singular peaks in density, followed by the accretional growth of embryo stars that form at these density peaks. Circumstellar discs often form from the gas being accreted by the forming stars, and accretion from these discs may be episodic, driven by gravitational instabilities or by protostellar interactions. Star-forming clouds typically develop filamentary structures, which may, along with the thermal physics, play an important role in the origin of stellar masses because of the sensitivity of filament fragmentation to temperature variations. Simulations of the formation of star clusters show that the most massive stars form by continuing accretion in the dense cluster cores, and this again is a runaway process that couples star formation and cluster formation. Star-forming clouds also tend to develop hierarchical structures, and smaller groups of forming objects tend to merge into progressively larger ones, a generic feature of self-gravitating systems that is common to star formation and galaxy formation. Because of the large range of scales and the complex dynamics involved, analytic models cannot adequately describe many aspects of star formation, and detailed numerical simulations are needed to advance our understanding of the subject. 'The purpose of computing is insight, not numbers.' Richard W Hamming, in Numerical Methods for Scientists and Engineers (1962) 'There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy.' William Shakespeare, in Hamlet, Prince of Denmark (1604) (key issues review)

  19. Diary Insights of an EFL Reading Teacher

    Directory of Open Access Journals (Sweden)

    Lopera Medina Sergio

    2013-10-01

    Full Text Available It is often argued that classroom diaries are subjective. This article explores the diary insights of a foreign language reading teacher. The inquiry was based on the following research question: What do the diary insights really evidence about the teaching practices of a foreign language reading teacher? As a research method, a case study was implemented. Five instruments were used to collect data: diary of the teacher, observations, questionnaires, tests, and focus groups. Given that motivation, interaction, reading improvement, and the application of reading strategies were supported by the research instruments, it would seem that a diary can be objective.A menudo se argumenta que los diarios de clase son subjetivos. En este artículo se exploran las apreciaciones que un profesor de lectura en inglés como lengua extranjera registra en su diario. La indagación se basó en la siguiente pregunta de investigación: ¿Qué apoya realmente las anotaciones de diario acerca de las prácticas de enseñanza de un profesor de lectura en lengua extranjera? Como método de estudio se implementó el estudio de caso. Se utilizaron cinco instrumentos para recolectar la información: diario del profesor, observaciones de clase, cuestionarios, exámenes y grupos focales. Dado que estos instrumentos de investigación incidieron en la motivación, la interacción, la mejoría en lectura y en la aplicación de las estrategias de lecturas, se podría concluir que un diario puede ser objetivo.

  20. The art of insight in science and engineering mastering complexity

    CERN Document Server

    Mahajan, Sanjoy

    2014-01-01

    In this book, Sanjoy Mahajan shows us that the way to master complexity is through insight rather than precision. Precision can overwhelm us with information, whereas insight connects seemingly disparate pieces of information into a simple picture. Unlike computers, humans depend on insight. Based on the author's fifteen years of teaching at MIT, Cambridge University, and Olin College, The Art of Insight in Science and Engineering shows us how to build insight and find understanding, giving readers tools to help them solve any problem in science and engineering. To master complexity, we can organize it or discard it. The Art of Insight in Science and Engineering first teaches the tools for organizing complexity, then distinguishes the two paths for discarding complexity: with and without loss of information. Questions and problems throughout the text help readers master and apply these groups of tools. Armed with this three-part toolchest, and without complicated mathematics, readers can estimate the flight ...

  1. Dimensions of insight in schizophrenia: Exploratory factor analysis of items from multiple self- and interviewer-rated measures of insight.

    Science.gov (United States)

    Konsztowicz, Susanna; Schmitz, Norbert; Lepage, Martin

    2018-03-10

    Insight in schizophrenia is regarded as a multidimensional construct that comprises aspects such as awareness of the disorder and recognition of the need for treatment. The proposed number of underlying dimensions of insight is variable in the literature. In an effort to identify a range of existing dimensions of insight, we conducted a factor analysis on combined items from multiple measures of insight. We recruited 165 participants with enduring schizophrenia (treated for >3years). Exploratory factor analysis was conducted on itemized scores from two interviewer-rated measures of insight: the Schedule for the Assessment of Insight-Expanded and the abbreviated Scale to assess Unawareness of Mental Disorder; and two self-report measures: the Birchwood Insight Scale and the Beck Cognitive Insight Scale. A five-factor solution was selected as the best-fitting model, with the following dimensions of insight: 1) awareness of illness and the need for treatment; 2) awareness and attribution of symptoms and consequences; 3) self-certainty; 4) self-reflectiveness for objectivity and fallibility; and 5) self-reflectiveness for errors in reasoning and openness to feedback. Insight in schizophrenia is a multidimensional construct comprised of distinct clinical and cognitive domains of awareness. Multiple measures of insight, both clinician- and self-rated, are needed to capture all of the existing dimensions of insight. Future exploration of associations between the various dimensions and their potential determinants will facilitate the development of clinically useful models of insight and effective interventions to improve outcome. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. New Insights into Non-Avian Dinosaur Reproduction and Their Evolutionary and Ecological Implications: Linking Fossil Evidence to Allometries of Extant Close Relatives

    Science.gov (United States)

    Werner, Jan; Griebeler, Eva Maria

    2013-01-01

    It has been hypothesized that a high reproductive output contributes to the unique gigantism in large dinosaur taxa. In order to infer more information on dinosaur reproduction, we established allometries between body mass and different reproductive traits (egg mass, clutch mass, annual clutch mass) for extant phylogenetic brackets (birds, crocodiles and tortoises) of extinct non-avian dinosaurs. Allometries were applied to nine non-avian dinosaur taxa (theropods, hadrosaurs, and sauropodomorphs) for which fossil estimates on relevant traits are currently available. We found that the reproductive traits of most dinosaurs conformed to similar-sized or scaled-up extant reptiles or birds. The reproductive traits of theropods, which are considered more bird-like, were indeed consistent with birds, while the traits of sauropodomorphs conformed better to reptiles. Reproductive traits of hadrosaurs corresponded to both reptiles and birds. Excluding Massospondylus carinatus , all dinosaurs studied had an intermediary egg to body mass relationship to reptiles and birds. In contrast, dinosaur clutch masses fitted with either the masses predicted from allometries of birds (theropods) or to the masses of reptiles (all other taxa). Theropods studied had probably one clutch per year. For sauropodomorphs and hadrosaurs, more than one clutch per year was predicted. Contrary to current hypotheses, large dinosaurs did not have exceptionally high annual egg numbers (AEN). Independent of the extant model, the estimated dinosaur AEN did not exceed 850 eggs (75,000 kg sauropod) for any of the taxa studied. This estimated maximum is probably an overestimation due to unrealistic assumptions. According to most AEN estimations, the dinosaurs studied laid less than 200 eggs per year. Only some AEN estimates obtained for medium to large sized sauropods were higher (200-400 eggs). Our results provide new (testable) hypotheses, especially for reproductive traits that are insufficiently

  3. New insights into non-avian dinosaur reproduction and their evolutionary and ecological implications: linking fossil evidence to allometries of extant close relatives.

    Directory of Open Access Journals (Sweden)

    Jan Werner

    Full Text Available It has been hypothesized that a high reproductive output contributes to the unique gigantism in large dinosaur taxa. In order to infer more information on dinosaur reproduction, we established allometries between body mass and different reproductive traits (egg mass, clutch mass, annual clutch mass for extant phylogenetic brackets (birds, crocodiles and tortoises of extinct non-avian dinosaurs. Allometries were applied to nine non-avian dinosaur taxa (theropods, hadrosaurs, and sauropodomorphs for which fossil estimates on relevant traits are currently available. We found that the reproductive traits of most dinosaurs conformed to similar-sized or scaled-up extant reptiles or birds. The reproductive traits of theropods, which are considered more bird-like, were indeed consistent with birds, while the traits of sauropodomorphs conformed better to reptiles. Reproductive traits of hadrosaurs corresponded to both reptiles and birds. Excluding Massospondyluscarinatus, all dinosaurs studied had an intermediary egg to body mass relationship to reptiles and birds. In contrast, dinosaur clutch masses fitted with either the masses predicted from allometries of birds (theropods or to the masses of reptiles (all other taxa. Theropods studied had probably one clutch per year. For sauropodomorphs and hadrosaurs, more than one clutch per year was predicted. Contrary to current hypotheses, large dinosaurs did not have exceptionally high annual egg numbers (AEN. Independent of the extant model, the estimated dinosaur AEN did not exceed 850 eggs (75,000 kg sauropod for any of the taxa studied. This estimated maximum is probably an overestimation due to unrealistic assumptions. According to most AEN estimations, the dinosaurs studied laid less than 200 eggs per year. Only some AEN estimates obtained for medium to large sized sauropods were higher (200-400 eggs. Our results provide new (testable hypotheses, especially for reproductive traits that are insufficiently

  4. New insights into non-avian dinosaur reproduction and their evolutionary and ecological implications: linking fossil evidence to allometries of extant close relatives.

    Science.gov (United States)

    Werner, Jan; Griebeler, Eva Maria

    2013-01-01

    It has been hypothesized that a high reproductive output contributes to the unique gigantism in large dinosaur taxa. In order to infer more information on dinosaur reproduction, we established allometries between body mass and different reproductive traits (egg mass, clutch mass, annual clutch mass) for extant phylogenetic brackets (birds, crocodiles and tortoises) of extinct non-avian dinosaurs. Allometries were applied to nine non-avian dinosaur taxa (theropods, hadrosaurs, and sauropodomorphs) for which fossil estimates on relevant traits are currently available. We found that the reproductive traits of most dinosaurs conformed to similar-sized or scaled-up extant reptiles or birds. The reproductive traits of theropods, which are considered more bird-like, were indeed consistent with birds, while the traits of sauropodomorphs conformed better to reptiles. Reproductive traits of hadrosaurs corresponded to both reptiles and birds. Excluding Massospondyluscarinatus, all dinosaurs studied had an intermediary egg to body mass relationship to reptiles and birds. In contrast, dinosaur clutch masses fitted with either the masses predicted from allometries of birds (theropods) or to the masses of reptiles (all other taxa). Theropods studied had probably one clutch per year. For sauropodomorphs and hadrosaurs, more than one clutch per year was predicted. Contrary to current hypotheses, large dinosaurs did not have exceptionally high annual egg numbers (AEN). Independent of the extant model, the estimated dinosaur AEN did not exceed 850 eggs (75,000 kg sauropod) for any of the taxa studied. This estimated maximum is probably an overestimation due to unrealistic assumptions. According to most AEN estimations, the dinosaurs studied laid less than 200 eggs per year. Only some AEN estimates obtained for medium to large sized sauropods were higher (200-400 eggs). Our results provide new (testable) hypotheses, especially for reproductive traits that are insufficiently documented

  5. Clinical and Cognitive Insight in a Compensatory Cognitive Training Intervention

    Science.gov (United States)

    Burton, Cynthia Z.; Vella, Lea; Twamley, Elizabeth W.

    2013-01-01

    The impact of limited insight is a crucial consideration in the treatment of individuals with psychiatric illness. In the context of psychosis, both clinical and cognitive insight have been described. This study aimed to evaluate the relationships between clinical and cognitive insight and neuropsychological functioning, psychiatric symptom severity, and everyday functioning in patients with a primary psychotic disorder participating in a compensatory cognitive training (CT) intervention. Sixty-nine individuals diagnosed with a primary psychotic disorder were randomized to a 3-month CT intervention or to standard pharmacotherapy, and they completed a comprehensive neuropsychological, clinical, and functional battery at baseline, 3 months, and 6 months. The CT intervention focused on habit formation and compensatory strategy learning in four domains: prospective memory, attention and vigilance, learning and memory, and problem-solving/cognitive flexibility. At baseline, better clinical insight was significantly related to better executive functioning and less severe negative symptoms. There was no significant association between cognitive insight and cognitive functioning, symptom severity, or everyday functioning ability. The CT intervention did not have an effect on clinical or cognitive insight, but better cognitive insight prior to participation in CT significantly predicted decreased positive and depressive symptom severity posttreatment, and better clinical insight predicted improved self-reported quality of life. Although clinical insight is related to executive functioning, the correlates of cognitive insight remain elusive. Intact insight appears to be beneficial in ameliorating clinical symptomatology like positive symptoms and depression, rather than augmenting cognition. It may be valuable to develop brief interventions aimed at improving clinical and cognitive insight prior to other psychosocial rehabilitation in order to maximize the benefit of

  6. INSIGHT AND SELF-STIGMA IN PATIENTS WITH SCHIZOPHRENIA.

    Science.gov (United States)

    Vidović, Domagoj; Brecić, Petrana; Vilibić, Maja; Jukić, Vlado

    2016-03-01

    Poor insight and high level of self-stigma are often present among patients with schizophrenia and are related to poorer treatment adherence, poorer social function and rehabilitation, aggressive behavior, higher level of depression, social anxiety, lower quality of life and self-esteem. Reports on a relationship between insight and stigma are controversial. We examined the relationship of the level of insight and self-stigma in a sample of 149 patients with schizophrenia. Insight was measured with the Scale to assess Unawareness of Mental Disorder and self-stigma with the Internalized Stigma of Mental Illness. Results showed 88.6% of the patients to have high or moderate insight, with a mean value of 2.73. General insight showed the highest level (2.58) and insight in positive symptoms the lowest level (2.9). The self-stigma score in general was 2.13, with stereotype endorsement being lowest (1.98). According to study results, 77.1% of patients felt minimal or low self-stigma across all subscales, except for stigma resistance subscale. Statistically significant correlation was found between insight and four subscales of self-stigma, while no correlation was found for the stigma resistance subscale only. These results imply the need of individually tailored antistigma and insight promoting programs for patients with schizophrenia.

  7. Insight in Schizophrenia: Relationship to Positive, Negative and Neurocognitive Dimensions

    Science.gov (United States)

    Joseph, Boban; Narayanaswamy, Janardhanan C.; Venkatasubramanian, Ganesan

    2015-01-01

    Impairment of insight is considered as the hallmark of schizophrenia. Substantial proportion of patients with schizophrenia has either poor or absent insight. Insight is a multidimensional and dynamic construct which appears to have intricate links with other symptom dimensions of the psychotic illness. A better appreciation of the association that insight shares with other symptom clusters in psychosis could help us in gaining knowledge about aetiology, prognosis and treatment-related facets of the disorder. This is likely to have critical implications in the understanding and therapeutics of schizophrenia. PMID:25722504

  8. Improving insight and non-insight problem solving with brief interventions.

    Science.gov (United States)

    Wen, Ming-Ching; Butler, Laurie T; Koutstaal, Wilma

    2013-02-01

    Developing brief training interventions that benefit different forms of problem solving is challenging. In earlier research, Chrysikou (2006) showed that engaging in a task requiring generation of alternative uses of common objects improved subsequent insight problem solving. These benefits were attributed to a form of implicit transfer of processing involving enhanced construction of impromptu, on-the-spot or 'ad hoc' goal-directed categorizations of the problem elements. Following this, it is predicted that the alternative uses exercise should benefit abilities that govern goal-directed behaviour, such as fluid intelligence and executive functions. Similarly, an indirect intervention - self-affirmation (SA) - that has been shown to enhance cognitive and executive performance after self-regulation challenge and when under stereotype threat, may also increase adaptive goal-directed thinking and likewise should bolster problem-solving performance. In Experiment 1, brief single-session interventions, involving either alternative uses generation or SA, significantly enhanced both subsequent insight and visual-spatial fluid reasoning problem solving. In Experiment 2, we replicated the finding of benefits of both alternative uses generation and SA on subsequent insight problem-solving performance, and demonstrated that the underlying mechanism likely involves improved executive functioning. Even brief cognitive- and social-psychological interventions may substantially bolster different types of problem solving and may exert largely similar facilitatory effects on goal-directed behaviours. © 2012 The British Psychological Society.

  9. Insight and satisfaction with life among adolescents with mental disorders: assessing associations with self-stigma and parental insight.

    Science.gov (United States)

    Gaziel, M; Hasson-Ohayon, I; Morag-Yaffe, M; Schapir, L; Zalsman, G; Shoval, G

    2015-02-01

    The purpose of the current study was to assess the associations of illness perception-related variables with satisfaction with life (SwL) among adolescents with mental disorders. Insight into mental disorder (SAI-E), Internalized stigma of mental illness (ISMI) and Multidimensional Students' Life Satisfaction Scale (MSLSS) were administrated to 30 adolescent patients. Adapted version for parents of the SAI-E was also administrated to 37 of their parents. Significant positive correlations were found between insight into the illness, self-stigma and parental insight. Insight and self-stigma were significantly negatively related to the total score of SwL and few of its dimensions while parental insight was significantly associated only with the SwL dimensions of school and self. Regression models revealed main negative effects of insight and self-stigma on SwL and no interaction effect. The possible independent contribution of insight and self-stigma to SwL should be addressed in interventions designed for family and adolescents coping with mental illness. Special attention should be given to the possible negative implications that insight possesses. In lack of support of the moderation role of self-stigma, reported in studies among adults with mental illness, future studies should trace other variables in order to further understand the insight paradox among adolescents. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  10. Insight in schizophrenia: involvement of self-reflection networks?

    Science.gov (United States)

    van der Meer, Lisette; de Vos, Annerieke E; Stiekema, Annemarie P M; Pijnenborg, Gerdina H M; van Tol, Marie-José; Nolen, Willem A; David, Anthony S; Aleman, André

    2013-11-01

    Impaired insight is a common feature in psychosis and an important predictor of variables such as functional outcome, prognosis, and treatment adherence. A cognitive process that may underlie insight in psychosis is self-reflection, or the conscious evaluation of one's traits and characteristics. The current study aims to investigate the neural correlates of self-reflective processing and its relationship with insight in schizophrenia. Forty-seven schizophrenia patients and 21 healthy controls performed a self-reflection task in a functional magnetic resonance imaging (fMRI) scanner. The tasks comprised a self-reflection, close other-reflection, and a semantic (baseline) condition. Insight scores were obtained with the Schedule of Assessment of Insight Expanded. In addition, cognitive insight scores were obtained (Beck Cognitive Insight Scale [BCIS]). Schizophrenia patients demonstrated less activation in the posterior cingulate cortex in the self- and other-reflection conditions and less activation in the precuneus in the other-reflection condition compared with healthy controls. Better insight was associated with greater response in the inferior frontal gyrus, anterior insula, and inferior parietal lobule during self-reflection. In addition, better cognitive insight was associated with higher activation in ventromedial prefrontal cortex during self-reflection. In the current study, evidence for a relationship between self-reflection and insight in patients with schizophrenia was found in brain areas related to self-reflection, self/other distinction and source attribution. The findings support the rationale for a treatment that is currently under evaluation, which attempts to increase insight by enhancing self-reflection.

  11. Insight in Schizophrenia: Involvement of Self-Reflection Networks?

    Science.gov (United States)

    de Vos, Annerieke E.

    2013-01-01

    Background: Impaired insight is a common feature in psychosis and an important predictor of variables such as functional outcome, prognosis, and treatment adherence. A cognitive process that may underlie insight in psychosis is self-reflection, or the conscious evaluation of one’s traits and characteristics. The current study aims to investigate the neural correlates of self-reflective processing and its relationship with insight in schizophrenia. Methods: Forty-seven schizophrenia patients and 21 healthy controls performed a self-reflection task in a functional magnetic resonance imaging (fMRI) scanner. The tasks comprised a self-reflection, close other-reflection, and a semantic (baseline) condition. Insight scores were obtained with the Schedule of Assessment of Insight Expanded. In addition, cognitive insight scores were obtained (Beck Cognitive Insight Scale [BCIS]). Results: Schizophrenia patients demonstrated less activation in the posterior cingulate cortex in the self- and other-reflection conditions and less activation in the precuneus in the other-reflection condition compared with healthy controls. Better insight was associated with greater response in the inferior frontal gyrus, anterior insula, and inferior parietal lobule during self-reflection. In addition, better cognitive insight was associated with higher activation in ventromedial prefrontal cortex during self-reflection. Conclusion: In the current study, evidence for a relationship between self-reflection and insight in patients with schizophrenia was found in brain areas related to self-reflection, self/other distinction and source attribution. The findings support the rationale for a treatment that is currently under evaluation, which attempts to increase insight by enhancing self-reflection. PMID:23104865

  12. The ADVANCE project: Insights and achievments

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    ADVANCE [Advanced Driver and Vehicle Advisory Navigation ConcEpt] was a public/private partnership conceived and developed by four founding parties. The founding parties include the Federal Highway Administration (FHWA), the Illinois Department of Transportation (IDOT), the University of Illinois at Chicago and Northwestern University operating together under the auspices of the Illinois Universities Transportation Research Consortium (IUTRC), and Motorola, Inc. The major responsibilities of each party are fully described in the Project agreement. Subsequently, these four were joined on the Steering Committee by the American Automobile Association (AAA). This unique blending of public sector, private sector and university interests, augmented by more than two dozen other private sector participants, provided a strong set of resources for ADVANCE. The ADVANCE test area covered over 300 square miles including portions of the City of Chicago and 40 northwest suburban communities. The Project encompasses the high growth areas adjacent to O`Hare International Airport, the Schaumburg/Hoffman Estates office and retail complexes, and the Lake-Cook Road development corridor. It also includes major sports and entertainment complexes such as the Arlington International Racecourse and the Rosemont Horizon. The population in the area is more than 750,000. The Insights and Perspectives Compendium is intended to provide useful information to project managers, system developers, and system integrators of future similar ITS implementations. It is intended for those that are technically interested in the ADVANCE Project and have a basic understanding of the project.

  13. Latest Insights on Adenovirus Structure and Assembly

    Directory of Open Access Journals (Sweden)

    Carmen San Martín

    2012-05-01

    Full Text Available Adenovirus (AdV capsid organization is considerably complex, not only because of its large size (~950 Å and triangulation number (pseudo T = 25, but also because it contains four types of minor proteins in specialized locations modulating the quasi-equivalent icosahedral interactions. Up until 2009, only its major components (hexon, penton, and fiber had separately been described in atomic detail. Their relationships within the virion, and the location of minor coat proteins, were inferred from combining the known crystal structures with increasingly more detailed cryo-electron microscopy (cryoEM maps. There was no structural information on assembly intermediates. Later on that year, two reports described the structural differences between the mature and immature adenoviral particle, starting to shed light on the different stages of viral assembly, and giving further insights into the roles of core and minor coat proteins during morphogenesis [1,2]. Finally, in 2010, two papers describing the atomic resolution structure of the complete virion appeared [3,4]. These reports represent a veritable tour de force for two structural biology techniques: X-ray crystallography and cryoEM, as this is the largest macromolecular complex solved at high resolution by either of them. In particular, the cryoEM analysis provided an unprecedented clear picture of the complex protein networks shaping the icosahedral shell. Here I review these latest developments in the field of AdV structural studies.

  14. Can Economics Provide Insights into Trust Infrastructure?

    Science.gov (United States)

    Vishik, Claire

    Many security technologies require infrastructure for authentication, verification, and other processes. In many cases, viable and innovative security technologies are never adopted on a large scale because the necessary infrastructure is slow to emerge. Analyses of such technologies typically focus on their technical flaws, and research emphasizes innovative approaches to stronger implementation of the core features. However, an observation can be made that in many cases the success of adoption pattern depends on non-technical issues rather than technology-lack of economic incentives, difficulties in finding initial investment, inadequate government support. While a growing body of research is dedicated to economics of security and privacy in general, few theoretical studies in this area have been completed, and even fewer that look at the economics of “trust infrastructure” beyond simple “cost of ownership” models. This exploratory paper takes a look at some approaches in theoretical economics to determine if they can provide useful insights into security infrastructure technologies and architectures that have the best chance to be adopted. We attempt to discover if models used in theoretical economics can help inform technology developers of the optimal business models that offer a better chance for quick infrastructure deployment.

  15. Insights into the Mechanisms of Chloroplast Division

    Directory of Open Access Journals (Sweden)

    Yamato Yoshida

    2018-03-01

    Full Text Available The endosymbiosis of a free-living cyanobacterium into an ancestral eukaryote led to the evolution of the chloroplast (plastid more than one billion years ago. Given their independent origins, plastid proliferation is restricted to the binary fission of pre-existing plastids within a cell. In the last 25 years, the structure of the supramolecular machinery regulating plastid division has been discovered, and some of its component proteins identified. More recently, isolated plastid-division machineries have been examined to elucidate their structural and mechanistic details. Furthermore, complex studies have revealed how the plastid-division machinery morphologically transforms during plastid division, and which of its component proteins play a critical role in generating the contractile force. Identifying the three-dimensional structures and putative functional domains of the component proteins has given us hints about the mechanisms driving the machinery. Surprisingly, the mechanisms driving plastid division resemble those of mitochondrial division, indicating that these division machineries likely developed from the same evolutionary origin, providing a key insight into how endosymbiotic organelles were established. These findings have opened new avenues of research into organelle proliferation mechanisms and the evolution of organelles.

  16. Sport-related anxiety: current insights

    Directory of Open Access Journals (Sweden)

    Ford JL

    2017-10-01

    Full Text Available Jessica L Ford, Kenneth Ildefonso, Megan L Jones, Monna Arvinen-Barrow Department of Kinesiology, Integrative Health Care & Performance Unit, University of Wisconsin-Milwaukee, Milwaukee, WI, USA Abstract: To date, much research has been devoted to understanding how anxiety can affect sport performance, both in practice and in competitive settings. It is well known that sport has the potential for high levels of stress and anxiety, and that practicing and employing a range of psychological strategies can be beneficial in anxiety management. Equally, growing evidence also suggests that anxiety can play a role in sport injury prevention, occurrence, rehabilitation, and the return to sport process. The purpose of this paper is to provide current insights into sport-related anxiety. More specifically, it will provide the reader with definitions and theoretical conceptualizations of sport-related anxiety. This will be followed by making a case for considering the term "performance" to be broader than activities associated with sport-related performance in practice and competition, by including performance activities associated with sport injury prevention, rehabilitation, and the return to sport process. The paper will then highlight the importance of recognizing early signs and symptoms of anxiety, and the potential need for referral. Finally, the conclusions will emphasize the need for appropriate, client-specific, and practitioner competent care for athletes experiencing sport-related anxiety. Keywords: anxiety, sport, performance, injury, sport medicine professional, sport psychology, mental health

  17. Causal inference, probability theory, and graphical insights.

    Science.gov (United States)

    Baker, Stuart G

    2013-11-10

    Causal inference from observational studies is a fundamental topic in biostatistics. The causal graph literature typically views probability theory as insufficient to express causal concepts in observational studies. In contrast, the view here is that probability theory is a desirable and sufficient basis for many topics in causal inference for the following two reasons. First, probability theory is generally more flexible than causal graphs: Besides explaining such causal graph topics as M-bias (adjusting for a collider) and bias amplification and attenuation (when adjusting for instrumental variable), probability theory is also the foundation of the paired availability design for historical controls, which does not fit into a causal graph framework. Second, probability theory is the basis for insightful graphical displays including the BK-Plot for understanding Simpson's paradox with a binary confounder, the BK2-Plot for understanding bias amplification and attenuation in the presence of an unobserved binary confounder, and the PAD-Plot for understanding the principal stratification component of the paired availability design. Published 2013. This article is a US Government work and is in the public domain in the USA.

  18. Insights into Conifer Giga-Genomes1

    Science.gov (United States)

    De La Torre, Amanda R.; Birol, Inanc; Bousquet, Jean; Ingvarsson, Pär K.; Jansson, Stefan; Jones, Steven J.M.; Keeling, Christopher I.; MacKay, John; Nilsson, Ove; Ritland, Kermit; Street, Nathaniel; Yanchuk, Alvin; Zerbe, Philipp; Bohlmann, Jörg

    2014-01-01

    Insights from sequenced genomes of major land plant lineages have advanced research in almost every aspect of plant biology. Until recently, however, assembled genome sequences of gymnosperms have been missing from this picture. Conifers of the pine family (Pinaceae) are a group of gymnosperms that dominate large parts of the world’s forests. Despite their ecological and economic importance, conifers seemed long out of reach for complete genome sequencing, due in part to their enormous genome size (20–30 Gb) and the highly repetitive nature of their genomes. Technological advances in genome sequencing and assembly enabled the recent publication of three conifer genomes: white spruce (Picea glauca), Norway spruce (Picea abies), and loblolly pine (Pinus taeda). These genome sequences revealed distinctive features compared with other plant genomes and may represent a window into the past of seed plant genomes. This Update highlights recent advances, remaining challenges, and opportunities in light of the publication of the first conifer and gymnosperm genomes. PMID:25349325

  19. Understanding whistleblowing: qualitative insights from nurse whistleblowers.

    Science.gov (United States)

    Jackson, Debra; Peters, Kath; Andrew, Sharon; Edenborough, Michel; Halcomb, Elizabeth; Luck, Lauretta; Salamonson, Yenna; Wilkes, Lesley

    2010-10-01

    This paper is a report of a study conducted to explore the reasons behind the decision to blow the whistle and provide insights into nurses' experiences of being whistleblowers. Whistleblowing is a stigmatized and hidden activity that carries considerable ramifications to all concerned. In the health sector, when episodes of poor practice or service provision are identified, it is frequently nurses who are the whistleblowers. Despite this, there is remarkably limited literature that explores nurses' experiences of whistleblowing. Qualitative narrative inquiry design. Data were collected in 2008 from 11 nurse whistleblowers using in-depth semi-structured interviews. Participants were drawn from a range of general and specialty clinical areas and experienced whistleblowing as highly stressful. The findings were clustered into three main themes, namely: (i) Reasons for whistleblowing: I just couldn't advocate, (ii) Feeling silenced: Nobody speaks out, and (iii) Climate of fear: You are just not safe. The whistleblowing nurses believed they were acting in accordance with a duty of care. There is a need for greater clarity about the role nurses have as patient advocates. Furthermore, there is need to develop clear guidelines that create opportunities for nurses to voice concerns and to ensure that healthcare systems respond in a timely and appropriate manner, and a need to foster a safe environment in which to raise issues of concern. © 2010 Blackwell Publishing Ltd.

  20. Marketing Green Fertilizers: Insights into Consumer Preferences

    Directory of Open Access Journals (Sweden)

    Johannes Dahlin

    2016-11-01

    Full Text Available In an effort to support the long-term viability of the bioenergy industry through an end market for digestate, we investigated purchasing preferences for fertilizer product features in the home gardening market. We conducted a discrete choice experiment (DCE, presenting 504 respondents with a total of 6048 product attribute choices in a simulated context that replicated the tradeoff decisions made in the real marketplace. We analyzed the choice data using a hierarchical Bayes estimate to generate part-worth utilities for fertilizer product attributes. We then conducted a latent class analysis to identify market segments that could be expected to respond to differentiated product design strategies. We were able to quantify both purchasing preferences for fertilizer product attributes as well as the importance of each attribute to the perceived utility of a product. We were further able to identify five distinct market segments that make clear the potential for differentiated strategies in the home gardening market. We found both negative and positive price sensitivities, with sociodemographically distinct subgroups that favored low-, mid-, and high-priced products. We also found purchasing preferences for brand status, product labeling and nutrient values. Our results provide insights that should help product managers in the biogas industry develop marketing strategies to integrate digestate into a sustainable energy production system.

  1. Energy transitions research: Insights and cautionary tales

    International Nuclear Information System (INIS)

    Grubler, Arnulf

    2012-01-01

    This short essay first reviews the pioneers of energy transition research both in terms of data as well as theories. Three major insights that have emerged from this nascent research fields are summarized highlighting the importance of energy end-use and services, the lengthy process of transitions, as well as the patterns that characterize successful scale up of technologies and industries that drive historical energy transitions. The essay concludes with cautionary notes also derived from historical experience. In order to trigger a next energy transition policies and innovation efforts need to be persistent and continuous, aligned, as well as balanced. It is argued that current policy frameworks in place invariably do not meet these criteria and need to change in order to successfully trigger a next energy transition towards sustainability. - Highlights: ► Includes the first literature review of early energy transition research. ► Summarizes three major research findings from the literature. ► Reviews policy implications of recent case studies of energy technology innovation. ► Argues that current policy frameworks are deficient in view of above lessons.

  2. Babesiosis: recent insights into an ancient disease.

    Science.gov (United States)

    Hunfeld, K-P; Hildebrandt, A; Gray, J S

    2008-09-01

    Ever since the discovery of parasitic inclusions in erythrocytes of cattle in Romania by Victor Babes at the end of the 19th century, newly recognised babesial pathogens continue to emerge around the world and the substantial public health impact of babesiosis on livestock and man is ongoing. Babesia are transmitted by ixodid ticks and infection of the host causes a host-mediated pathology and erythrocyte lysis, resulting in anemia, hyperbilirubinuria, hemoglobinuria, and possibly organ failure. Recently obtained molecular data, particularly for the 18S rRNA gene, has contributed significantly to a better understanding of the sometimes puzzling phylogenetic situation of the genus Babesia and new information has been added to help determine the taxonomic position of many species. Moreover, it seems that owing to higher medical awareness the number of reported cases in humans is rising steadily. Hitherto unknown zoonotic babesias are now being reported from geographical areas where babesiosis was not known to occur and the growing numbers of immunocompromised individuals suggest that the frequency of cases will continue to rise. This review covers recent insights into human babesiosis with regard to phylogeny, diagnostics and treatment in order to provide new information on well known as well as recently discovered parasites with zoonotic potential.

  3. Ionomer Dynamics: Insights from Broadband Dielectric Spectroscopy

    Science.gov (United States)

    Runt, James

    2015-03-01

    Ionomers (polymers containing ionic functionality) have been traditionally used as packaging materials and in molding applications, and are now of increasing interest as candidate single ion conductors for energy storage devices, in energy conversion, and for other electroactive materials applications. The focus of this presentation is on the insight that broadband dielectric (impedance) spectroscopy brings to our understanding of ion and polymer dynamics of this family of materials. As an example of our recent work on relatively conductive ionomers, the first portion of the presentation will focus on anion conducting polyphosphazene ionomers, in which polymer bound cations are quaternized with either short alkyl or short ether oxygen chains. The low Tg, amorphous nature, and cation-solvating backbone distinguish polyphosphazenes as promising materials for ion conduction, the iodide variants being of particular interest in solar cells. In the second part of this overview, the first findings on the molecular dynamics of linear precise polyethylene-based ionomers containing 1-methylimidazolium bromide pendants on exactly every 9th, 15th, or 21st carbon atom will be summarized. In order to develop a robust interpretation of the dynamics of these materials, it is imperative to develop a thorough understanding of microphase separation (e.g. ion aggregation), and each of the above studies is complimented by multiangle X-ray scattering experiments. Supported by the NSF Polymers Program and DOE Basic Energy Sciences.

  4. Temporal Processing in Audition: Insights from Music.

    Science.gov (United States)

    Rajendran, Vani G; Teki, Sundeep; Schnupp, Jan W H

    2017-11-03

    Music is a curious example of a temporally patterned acoustic stimulus, and a compelling pan-cultural phenomenon. This review strives to bring some insights from decades of music psychology and sensorimotor synchronization (SMS) literature into the mainstream auditory domain, arguing that musical rhythm perception is shaped in important ways by temporal processing mechanisms in the brain. The feature that unites these disparate disciplines is an appreciation of the central importance of timing, sequencing, and anticipation. Perception of musical rhythms relies on an ability to form temporal predictions, a general feature of temporal processing that is equally relevant to auditory scene analysis, pattern detection, and speech perception. By bringing together findings from the music and auditory literature, we hope to inspire researchers to look beyond the conventions of their respective fields and consider the cross-disciplinary implications of studying auditory temporal sequence processing. We begin by highlighting music as an interesting sound stimulus that may provide clues to how temporal patterning in sound drives perception. Next, we review the SMS literature and discuss possible neural substrates for the perception of, and synchronization to, musical beat. We then move away from music to explore the perceptual effects of rhythmic timing in pattern detection, auditory scene analysis, and speech perception. Finally, we review the neurophysiology of general timing processes that may underlie aspects of the perception of rhythmic patterns. We conclude with a brief summary and outlook for future research. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Young Children's Analogical Problem Solving: Gaining Insights from Video Displays

    Science.gov (United States)

    Chen, Zhe; Siegler, Robert S.

    2013-01-01

    This study examined how toddlers gain insights from source video displays and use the insights to solve analogous problems. Two- to 2.5-year-olds viewed a source video illustrating a problem-solving strategy and then attempted to solve analogous problems. Older but not younger toddlers extracted the problem-solving strategy depicted in the video…

  6. Visual Attention Modulates Insight versus Analytic Solving of Verbal Problems

    Science.gov (United States)

    Wegbreit, Ezra; Suzuki, Satoru; Grabowecky, Marcia; Kounios, John; Beeman, Mark

    2012-01-01

    Behavioral and neuroimaging findings indicate that distinct cognitive and neural processes underlie solving problems with sudden insight. Moreover, people with less focused attention sometimes perform better on tests of insight and creative problem solving. However, it remains unclear whether different states of attention, within individuals,…

  7. Adaptation Insights: Lessons from participatory research in Africa ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    21 avr. 2016 ... The Adaptation Insights series consists of nine case studies from seven projects supported by the Climate Change Adaptation in Africaprogram. Each brief presents insights from research carried out with the active involvement of communities at risk from climate change. The series includes case studies ...

  8. Insight in Schizophrenia : Involvement of Self-Reflection Networks?

    NARCIS (Netherlands)

    van der Meer, Lisette; de Vos, Annerieke E.; Stiekema, Annemarie P. M.; Pijnenborg, Gerdina H. M.; van Tol, Marie-Jose; Nolen, Willem A.; David, Anthony S.; Aleman, Andre

    2013-01-01

    Background: Impaired insight is a common feature in psychosis and an important predictor of variables such as functional outcome, prognosis, and treatment adherence. A cognitive process that may underlie insight in psychosis is self-reflection, or the conscious evaluation of one's traits and

  9. Neural activity when people solve verbal problems with insight.

    Directory of Open Access Journals (Sweden)

    Mark Jung-Beeman

    2004-04-01

    Full Text Available People sometimes solve problems with a unique process called insight, accompanied by an "Aha!" experience. It has long been unclear whether different cognitive and neural processes lead to insight versus noninsight solutions, or if solutions differ only in subsequent subjective feeling. Recent behavioral studies indicate distinct patterns of performance and suggest differential hemispheric involvement for insight and noninsight solutions. Subjects solved verbal problems, and after each correct solution indicated whether they solved with or without insight. We observed two objective neural correlates of insight. Functional magnetic resonance imaging (Experiment 1 revealed increased activity in the right hemisphere anterior superior temporal gyrus for insight relative to noninsight solutions. The same region was active during initial solving efforts. Scalp electroencephalogram recordings (Experiment 2 revealed a sudden burst of high-frequency (gamma-band neural activity in the same area beginning 0.3 s prior to insight solutions. This right anterior temporal area is associated with making connections across distantly related information during comprehension. Although all problem solving relies on a largely shared cortical network, the sudden flash of insight occurs when solvers engage distinct neural and cognitive processes that allow them to see connections that previously eluded them.

  10. Characteristics of Kodak Insight, an F-speed intraoral film.

    Science.gov (United States)

    Ludlow, J B; Platin, E; Mol, A

    2001-01-01

    This study reports film speed, contrast, exposure latitude, resolution, and response to processing solution depletion of Kodak Insight intraoral film. Densitometric curves were generated by using International Standards Organization protocol. Additional curves were generated for Ultra-speed, Ektaspeed Plus, and Insight films developed in progressively depleted processing solutions. Eight observers viewed images of a resolution test tool for maximum resolution assessment. Images of an aluminum step-wedge were reviewed to determine useful exposure latitude. Insight's sensitivity in fresh automatic processor solutions places it in the F-speed group. An average gradient of 1.8 was found with all film types. Insight provided 93% of the useful exposure latitude of Ektaspeed Plus film. Insight maintained contrast in progressively depleted processing solutions. Like Ektaspeed Plus, Insight was able to resolve at least 20 line-pairs per millimeter. Under International Standards Organization conditions, Insight required only 77% of the exposure of Ektaspeed Plus film. Insight film provided stable contrast in depleted processing solutions.

  11. Training for Future Operations: Digital Leaders' Transformation Insights

    National Research Council Canada - National Science Library

    Johnston, John

    2003-01-01

    ... and insights to expand the understanding of issues and requirements Finally, the team developed specific recommendations intended to give transformation leaders a distinctive training advantage The practical insights and recommendations point to initiatives the Army can take to establish Objective Force training as a decisive combat multiplier.

  12. Improved understanding of protein complex offers insight into DNA

    Science.gov (United States)

    Summer Science Writing Internship Improved understanding of protein complex offers insight into DNA clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication

  13. REFLEX : A metacognitive group treatment to improve insight in psychosis

    NARCIS (Netherlands)

    Pijnenborg, M.; Van der Meer, L.; De Vos, A.; Bockting, C. L. H.; Van der Gaag, M.; Aleman, A.

    2013-01-01

    Background: Many people with schizophrenia (50-80%) demonstrate impaired insight. A number of interventions aiming to improve insight have been proposed and evaluated, for example cognitive behavioral therapy and psycho-education. Results of these interventions leave room for improvement. Therefore,

  14. Insight in psychosis: Standards, science, ethics and value judgment.

    Science.gov (United States)

    Jacob, K S

    2017-06-01

    The clinical assessment of insight solely employs biomedical perspectives and criteria to the complete exclusion of context and culture and to the disregard of values and value judgments. The aim of this discussion article is to examine recent research from India on insight and explanatory models in psychosis and re-examine the framework of assessment, diagnosis and management of insight and explanatory models. Recent research from India on insight in psychosis and explanatory models is reviewed. Recent research, which has used longitudinal data and adjusted for pretreatment variables, suggests that insight and explanatory models of illness at baseline do not predict course, outcome and treatment response in schizophrenia, which seem to be dependent on the severity and quality of the psychosis. It supports the view that people with psychosis simultaneously hold multiple and contradictory explanatory models of illness, which change over time and with the trajectory of the illness. It suggests that insight, like all explanatory models, is a narrative of the person's reality and a coping strategy to handle with the varied impact of the illness. This article argues that the assessment of insight necessarily involves value entailments, commitments and consequences. It supports a need for a broad-based approach to assess awareness, attribution and action related to mental illness and to acknowledge the role of values and value judgment in the evaluation of insight in psychosis.

  15. Productive and Re-Productive Thinking in Solving Insight Problems

    Science.gov (United States)

    Cunningham, J. Barton; MacGregor, James N.

    2014-01-01

    Many innovations in organizations result when people discover insightful solutions to problems. Insightful problem-solving was considered by Gestalt psychologists to be associated with productive, as opposed to re-productive, thinking. Productive thinking is characterized by shifts in perspective which allow the problem solver to consider new,…

  16. Insight and illness perception in Mexican patients with psychosis.

    Science.gov (United States)

    Gómez-de-Regil, Lizzette

    2015-03-01

    Insight and illness perception are two concepts of interest in the study of factors related to clinical outcome in patients with psychosis. Insight implies a risk of emotional distress for the patient. Illness perceptions, regardless of their accuracy, might be favorable or not to illness. Literature provides evidence of significant correlates of these factors with clinical outcome, but they are rarely included in a single study. 1) assessing insight and illness perception in a sample of Mexican patients who have experienced psychosis and, 2) analyzing how insight and illness perception relate to each other and how they relate to clinical status (i.e., positive, negative, and general psychopathology, depression, and anxiety). Sixty-one participants (55.7% females) were recruited from a public psychiatric hospital; insight and illness perceptions were assessed with the SUMD and the Brief-IPQ, respectively. Clinical status was assessed with the PANSS, CDS and BAI scales. Participants showed good insight, favorable illness perceptions for the cognitive and comprehension dimensions, but unfavorable for the emotional dimension. Clinical status of sample was characterized by mild symptoms. Poor insight related to positive symptoms and general psychopathology. Cognitive and emotional perceptions of illness were significantly associated to most clinical status parameters, whereas comprehension showed no significant results. The study not only replicates the significant association on insight and illness perception with clinical outcome, but shows how their patterns of interactions are different, reinforcing the idea that they are two distinct factors worthy of being habitually acknowledged in research and clinical practice.

  17. Mind Wandering and the Incubation Effect in Insight Problem Solving

    Science.gov (United States)

    Tan, Tengteng; Zou, Hong; Chen, Chuansheng; Luo, Jin

    2015-01-01

    Although many anecdotes suggest that creative insights often arise during mind wandering, empirical research is still sparse. In this study, the number reduction task (NRT) was used to assess whether insightful solutions were related to mind wandering during the incubation stage of the creative process. An experience sampling paradigm was used to…

  18. Insight and suicidality in psychosis: A cross-sectional study.

    Science.gov (United States)

    Massons, Carmen; Lopez-Morinigo, Javier-David; Pousa, Esther; Ruiz, Ada; Ochoa, Susana; Usall, Judith; Nieto, Lourdes; Cobo, Jesus; David, Anthony S; Dutta, Rina

    2017-06-01

    We aimed to test whether specific insight dimensions are associated with suicidality in patients with psychotic disorders. 143 patients with schizophrenia spectrum disorders were recruited. Suicidality was assessed by item 8 of the Calgary Depression Scale for Schizophrenia (CDSS). Insight was measured by the Scale of Unawareness of Mental Disorder (SUMD) and the Markova and Berrios Insight Scale. Bivariate analyses and multivariable logistic regression models were conducted. Those subjects aware of having a mental illness and its social consequences had higher scores on suicidality than those with poor insight. Awareness of the need for treatment was not linked with suicidality. The Markova and Berrios Insight scale total score and two specific domains (awareness of "disturbed thinking and loss of control over the situation" and "having a vague feeling that something is wrong") were related to suicidality. However, no insight dimensions survived the multivariable regression model, which found depression and previous suicidal behaviour to predict suicidality. Suicidality in psychosis was linked with some insight dimensions: awareness of mental illness and awareness of social consequences, but not compliance. Depression and previous suicidal behaviour mediated the associations with insight; thus, predicting suicidality. Copyright © 2017. Published by Elsevier B.V.

  19. Insight and its relationship with stigma in psychiatric patients

    Directory of Open Access Journals (Sweden)

    Deepak K Mishra

    2009-01-01

    Full Text Available Background: The literature on insight has paid insufficient attention to the social experiences that are associated with receiving and endorsing a diagnosis of mental illness. The psychological and behavioral commitments associated with insight extend beyond agreeing with a diagnosis and accepting treatment to include taking on the identity of an individual diagnosed with mental illness. This study sought to examine the relationship between insight and stigma in psychiatric patients. Materials and Methods: Cross-sectional assessment of insight and stigma was done using the system adopted by Kaplan and Sadock in their comprehensive textbook of psychiatry and Felt Stigma Scale in 100 psychiatric patients (40 patients suffering from Bipolar affective disorder, 30 Schizophrenics, 20 Substance dependents and 10 with Obsessive Compulsive disorder. Results: It was found that the level of stigma felt by patients with insight was significantly higher than that felt by patients without insight. Conclusion: Though there is a certain extent of stigma present in patients without insight, as is expected, the level of stigma increases as the patients develop insight.

  20. INSIGHT AGONISTES: A READING OF SOPHOCLES'S OEDIPUS THE KING.

    Science.gov (United States)

    Mahon, Eugene J

    2015-07-01

    In this reading of Sophocles's Oedipus the King, the author suggests that insight can be thought of as the main protagonist of the tragedy. He personifies this depiction of insight, calling it Insight Agonistes, as if it were the sole conflicted character on the stage, albeit masquerading at times as several other characters, including gods, sphinxes, and oracles. This psychoanalytic reading of the text lends itself to an analogy between psychoanalytic process and Sophocles's tragic hero. The author views insight as always transgressing against, always at war with a conservative, societal, or intrapsychic chorus of structured elements. A clinical vignette is presented to illustrate this view of insight. © 2015 The Psychoanalytic Quarterly, Inc.

  1. The Association of DRD2 with Insight Problem Solving.

    Science.gov (United States)

    Zhang, Shun; Zhang, Jinghuan

    2016-01-01

    Although the insight phenomenon has attracted great attention from psychologists, it is still largely unknown whether its variation in well-functioning human adults has a genetic basis. Several lines of evidence suggest that genes involved in dopamine (DA) transmission might be potential candidates. The present study explored for the first time the association of dopamine D2 receptor gene ( DRD2 ) with insight problem solving. Fifteen single-nucleotide polymorphisms (SNPs) covering DRD2 were genotyped in 425 unrelated healthy Chinese undergraduates, and were further tested for association with insight problem solving. Both single SNP and haplotype analysis revealed several associations of DRD2 SNPs and haplotypes with insight problem solving. In conclusion, the present study provides the first evidence for the involvement of DRD2 in insight problem solving, future studies are necessary to validate these findings.

  2. Inspiration & Insight - a tribute to Niels Reeh

    Science.gov (United States)

    Ahlstrom, A. P.; Vieli, A.

    2009-12-01

    Niels Reeh was highly regarded for his contributions to glaciology, specifically through his rigorous combination of numerical modelling and field observations. In 1966 he began his work on the application of beam mechanics to floating glaciers and ice shelves and throughout his life, Niels retained a strong interest in modelling glacier dynamics. In the early 1980s Niels developed a 3D-model for ice sheets and in the late 1980s an advanced flow-line model. Niels Reeh also took part in the early ice-core drilling efforts in Greenland and later pioneered the concept of retrieving similar records from the surface of the ice-sheet margin. Mass balance of glaciers and ice sheets was another theme in Niels Reeh’s research, with a number of important contributions and insights still used when teaching the subject to students. Niels developed elegant models for ablation and snow densification, notable for their applicability in large-scale ice-sheet models and studied the impact of climate change on ice sheets and glaciers. Niels also took his interest in ice-dynamics and mass balance into remote sensing and worked successfully on methods to utilize radar and laser data from airborne surveys and satellites in glaciology. In this, he pioneered the combination of field experiments, satellite observations and numerical modelling to solve problems on the Greenland Ice Sheet. In this presentation we will attempt to provide an overview of Niels Reeh’s many-facetted career in acknowledgement of his contributions to the field of glaciology.

  3. Carbonate landscapes evolution: Insights from 36Cl

    Science.gov (United States)

    Godard, Vincent; Thomas, Franck; Ollivier, Vincent; Bellier, Olivier; Shabanian, Esmaeil; Miramont, Cécile; Fleury, Jules; Benedetti, Lucilla; Guillou, Valéry; Aster Team

    2017-04-01

    Carbonate landscapes cover a significant fraction of the Earth surface, but their long-term dynamics is still poorly understood. When comparing with the situation in areas underlain by quartz-rich lithologies, where the routine use of 10Be-derived denudation rates has delivered fundamental insights on landscape evolution processes, this knowledge gap is particularly notable. Recent advances in the measurement of 36Cl and better understanding of its production pathways has opened the way to the development of a similar physically-based and quantitative analysis of landscape evolution in carbonate settings. However, beyond these methodological considerations, we still face fundamental geomorphological open questions, as for example the assessment of the importance of congruent carbonate dissolution in long-wavelength topographic evolution. Such unresolved problems concerning the relative importance of physical and chemical weathering processes lead to question the applicability of standard slope-dependent Geomorphic Transport Laws in carbonate settings. These issues have been addressed studying the geomorphological evolution of selected limestone ranges in Provence, SE France, where 36Cl concentration measurements in bedrock and stream sediment samples allow constraining denudation over 10 ka time-scale. We first identify a significant denudation contrast between the summit surface and the flanks of the ranges, pointing to a substantial contribution of gravity-driven processes to the landscape evolution, in addition to dissolution. Furthermore, a detailed analysis of the relationships between hillslope morphology and hilltop denudation allow to identify a fundamental transition between two regimes: (1) a dynamics where hillslope evolution is controlled by linear diffusive downslope regolith transport; and, (2) a domain where denudation is limited by the rate at which physical and chemical weathering processes can produce clasts and lower the hilltop. Such an abrupt

  4. Neural correlates of fear: insights from neuroimaging

    Directory of Open Access Journals (Sweden)

    Garfinkel SN

    2014-12-01

    the insights into fear, anxiety, and avoidance at the individual level extrapolate to groups and populations and can be meaningfully applied to economics, prejudice, and politics. Fear is ultimately a contagious social emotion. Keywords: amygdala, anxiety, arousal, autonomic, emotion, phobia

  5. Dispositional Insight Scale: Development and Validation of a Tool That Measures Propensity toward Insight in Problem Solving

    Science.gov (United States)

    Ovington, Linda A.; Saliba, Anthony J.; Goldring, Jeremy

    2016-01-01

    This article reports the development of a brief self-report measure of dispositional insight problem solving, the Dispositional Insight Scale (DIS). From a representative Australian database, 1,069 adults (536 women and 533 men) completed an online questionnaire. An exploratory and confirmatory factor analysis revealed a 5-item scale, with all…

  6. How to Detect Insight Moments in Problem Solving Experiments

    Directory of Open Access Journals (Sweden)

    Ruben E. Laukkonen

    2018-03-01

    Full Text Available Arguably, it is not possible to study insight moments during problem solving without being able to accurately detect when they occur (Bowden and Jung-Beeman, 2007. Despite over a century of research on the insight moment, there is surprisingly little consensus on the best way to measure them in real-time experiments. There have also been no attempts to evaluate whether the different ways of measuring insight converge. Indeed, if it turns out that the popular measures of insight diverge, then this may indicate that researchers who have used one method may have been measuring a different phenomenon to those who have used another method. We compare the strengths and weaknesses of the two most commonly cited ways of measuring insight: The feelings-of-warmth measure adapted from Metcalfe and Wiebe (1987, and the self-report measure adapted from Bowden and Jung-Beeman (2007. We find little empirical agreement between the two measures, and conclude that the self-report measure of Aha! is superior both methodologically and theoretically, and provides a better representation of what is commonly regarded as insight. We go on to describe and recommend a novel visceral measure of insight using a dynamometer as described in Creswell et al. (2016.

  7. How to Detect Insight Moments in Problem Solving Experiments.

    Science.gov (United States)

    Laukkonen, Ruben E; Tangen, Jason M

    2018-01-01

    Arguably, it is not possible to study insight moments during problem solving without being able to accurately detect when they occur (Bowden and Jung-Beeman, 2007). Despite over a century of research on the insight moment, there is surprisingly little consensus on the best way to measure them in real-time experiments. There have also been no attempts to evaluate whether the different ways of measuring insight converge. Indeed, if it turns out that the popular measures of insight diverge , then this may indicate that researchers who have used one method may have been measuring a different phenomenon to those who have used another method. We compare the strengths and weaknesses of the two most commonly cited ways of measuring insight: The feelings-of-warmth measure adapted from Metcalfe and Wiebe (1987), and the self-report measure adapted from Bowden and Jung-Beeman (2007). We find little empirical agreement between the two measures, and conclude that the self-report measure of Aha! is superior both methodologically and theoretically, and provides a better representation of what is commonly regarded as insight. We go on to describe and recommend a novel visceral measure of insight using a dynamometer as described in Creswell et al. (2016).

  8. A study of poor insight in social anxiety disorder.

    Science.gov (United States)

    Vigne, Paula; de Menezes, Gabriela B; Harrison, Ben J; Fontenelle, Leonardo F

    2014-11-30

    We investigated levels of insight among patients with Social Anxiety Disorder (SAD) as compared to patients with Obsessive-Compulsive Disorder (OCD) and evaluated whether levels of insight in SAD were related to specific sociodemographic and/or clinical features. Thirty-seven SAD patients and 51 OCD patients attending a tertiary obsessive-compulsive and anxiety disorders clinic were assessed with a sociodemographic and clinical questionnaire, a structured diagnostic interview, the Brown Assessment of Beliefs Scale (BABS), the Social Phobia Inventory (SPIN), the Beck Depression Inventory (BDI), the Sheehan Disability Scale (SDS), and the Treatment Adherence Survey-patient version (TAS-P). According to the BABS, SAD patients exhibited insight levels that were as low as those exhibited by OCD patients, with up to 29.7% of them being described as "poor insight" SAD. Although poor insight SAD patients were more frequently married, less depressed and displayed a statistical trend towards greater rates of early drop-out from cognitive-behavioral therapy, their insight levels were not associated with other variables of interest, including sex, age, employment, age at onset, duration of illness, associated psychiatric disorders, SPIN and SDS scores. Patients with poor insight SAD might perceive their symptoms as being less distressful and thus report fewer depressive symptoms and high rates of treatment non-adherence. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  9. Diagnostic accuracy of insight intraoral film on dental caries

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Young Nam; Lee, Byung Do [Wonkwang University College of Medicine, Iksan (Korea, Republic of); Lee, Sang Rae [Kyunghee University College of Medicine, Seoul (Korea, Republic of)

    2004-03-15

    To compare the diagnostic accuracy of Kodak Insight film with other intra-oral films in the detection of dental caries. Periapical radiographs of 99 extracted human teeth with sound proximal surfaces and interproximal artificial cavities were made on Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Kodak Insight films and automatically processed. Six dentists examined the presence of dental caries using a five-point confidence rating scale and compared the diagnostic accuracy by ROC (Receiver Operating Characteristic) analysis and ANOVA test. The sensitivity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.84, 0.77, 0.75 and 0.79 respectively. The specificity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.97, 0.95, 0.96 and 0.94 respectively. The mean ROC areas (Az) of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.917, 0.910, 0.894, 0.909 respectively. There was no significant differences between Az of Insight film and other films (p = 0.178). Theses results suggested that Kodak Insight film have the comparative diagnostic accuracy of dental caries with Ultraspeed and Ektaspeed films. (77)

  10. Diagnostic accuracy of insight intraoral film on dental caries

    International Nuclear Information System (INIS)

    Yoon, Young Nam; Lee, Byung Do; Lee, Sang Rae

    2004-01-01

    To compare the diagnostic accuracy of Kodak Insight film with other intra-oral films in the detection of dental caries. Periapical radiographs of 99 extracted human teeth with sound proximal surfaces and interproximal artificial cavities were made on Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Kodak Insight films and automatically processed. Six dentists examined the presence of dental caries using a five-point confidence rating scale and compared the diagnostic accuracy by ROC (Receiver Operating Characteristic) analysis and ANOVA test. The sensitivity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.84, 0.77, 0.75 and 0.79 respectively. The specificity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.97, 0.95, 0.96 and 0.94 respectively. The mean ROC areas (Az) of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.917, 0.910, 0.894, 0.909 respectively. There was no significant differences between Az of Insight film and other films (p = 0.178). Theses results suggested that Kodak Insight film have the comparative diagnostic accuracy of dental caries with Ultraspeed and Ektaspeed films. (77)

  11. Technical Insights for Saltstone PA Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Flach, G.; Sarkar, S.; Mahadevan, S.; Kosson, D.

    2011-07-20

    compatibility with existing CBP expertise and already-planned activities. Based on these criteria, the five original topics were down-selected to two: external sulfate attack and mechanistic geochemical prediction. For each of the selected topics, the CBP communicated with the PA analysts and subject matter experts at Savannah River to acquire input data specific to the Saltstone facility and related laboratory experiments. Simulations and analyses were performed for both topics using STADIUM (SIMCO 2008), LeachXS/ORCHESTRA (ECN 2007, Meeussen 2003), and other software tools. These supplemental CBP analyses produced valuable technical insights that can be used to strengthen the Saltstone PA using the ongoing PA maintenance process. This report in part summarizes key information gleaned from more comprehensive documents prepared by Sarkar et al. (2010), Samson (2010), and Sarkar (2010).

  12. Decision insight into stakeholder conflict for ERN.

    Energy Technology Data Exchange (ETDEWEB)

    Siirola, John; Tidwell, Vincent Carroll; Benz, Zachary O.; Stansbury, Melanie; Richards, Elizabeth H.; Turnley, Jessica Glicken (Galisteo Consulting); Warrender, Christina E.; Morrow, James Dan

    2012-02-01

    Participatory modeling has become an important tool in facilitating resource decision making and dispute resolution. Approaches to modeling that are commonly used in this context often do not adequately account for important human factors. Current techniques provide insights into how certain human activities and variables affect resource outcomes; however, they do not directly simulate the complex variables that shape how, why, and under what conditions different human agents behave in ways that affect resources and human interactions related to them. Current approaches also do not adequately reveal how the effects of individual decisions scale up to have systemic level effects in complex resource systems. This lack of integration prevents the development of more robust models to support decision making and dispute resolution processes. Development of integrated tools is further hampered by the fact that collection of primary data for decision-making modeling is costly and time consuming. This project seeks to develop a new approach to resource modeling that incorporates both technical and behavioral modeling techniques into a single decision-making architecture. The modeling platform is enhanced by use of traditional and advanced processes and tools for expedited data capture. Specific objectives of the project are: (1) Develop a proof of concept for a new technical approach to resource modeling that combines the computational techniques of system dynamics and agent based modeling, (2) Develop an iterative, participatory modeling process supported with traditional and advance data capture techniques that may be utilized to facilitate decision making, dispute resolution, and collaborative learning processes, and (3) Examine potential applications of this technology and process. The development of this decision support architecture included both the engineering of the technology and the development of a participatory method to build and apply the technology

  13. Technical Insights for Saltstone PA Maintenance

    International Nuclear Information System (INIS)

    Flach, G.; Sarkar, S.; Mahadevan, S.; Kosson, D.

    2011-01-01

    compatibility with existing CBP expertise and already-planned activities. Based on these criteria, the five original topics were down-selected to two: external sulfate attack and mechanistic geochemical prediction. For each of the selected topics, the CBP communicated with the PA analysts and subject matter experts at Savannah River to acquire input data specific to the Saltstone facility and related laboratory experiments. Simulations and analyses were performed for both topics using STADIUM (SIMCO 2008), LeachXS/ORCHESTRA (ECN 2007, Meeussen 2003), and other software tools. These supplemental CBP analyses produced valuable technical insights that can be used to strengthen the Saltstone PA using the ongoing PA maintenance process. This report in part summarizes key information gleaned from more comprehensive documents prepared by Sarkar et al. (2010), Samson (2010), and Sarkar (2010).

  14. JUST Revisited: Panchronic and Contrastive Insights

    Directory of Open Access Journals (Sweden)

    Manuela Romano

    2012-06-01

    Full Text Available Contrastive studies of cognate pragmatic markers involving modality have become increasingly salient in recent times. In describing semantic and discursive differences in different languages and language families, these studies are paving the way for a better understanding of grammaticalization, pragmaticalization and (intersubjectification paths. The present paper aims at contributing to the discussion by means of providing a synchronic and diachronic account of the marker JUST that combines semasiological and onomasiological insights. As thoroughly described in previous studies, JUST is a complex polycentric category in which overlapping nuances have been activated over time. In English and in other languages, the diachronic evolution of JUST involves an increasing semantic expansion from scalar to subjectified meanings and an increasing restriction in grammatical flexibility. However, polysemization and the emergence of grammaticalized readings seem to have gone further in English than in other languages. The present study, situated within the emerging field of panchronic cross-linguistic research on discourse markers, aims at ascertaining why.El estudio contrastivo de los marcadores pragmáticos de modalidad ocupa una posición central en el campo de la gramaticalización, la pragmaticalización y la (intersubjetivización, ya que permite trazar rutas de cambio a través de la descripción de peculiaridades semánticas y discursivas en distintas lenguas y familias lingüísticas. Este trabajo contribuye al debate ofreciendo un análisis semasiológico y onomasiológico del marcador JUST en sincronía y diacronía. Se trata de una categoría policéntrica en la que se han ido activando lecturas cruzadas a lo largo del tiempo. Su evolución está marcada, tanto en inglés como en otras lenguas, por una expansión semántica cada vez mayor, transitando desde lecturas escalares hacia lecturas subjetivizadas, y por una flexibilidad gramatical

  15. Solving Classical Insight Problems without Aha! Experience: 9 Dot, 8 Coin, and Matchstick Arithmetic Problems

    Science.gov (United States)

    Danek, Amory H.; Wiley, Jennifer; Öllinger, Michael

    2016-01-01

    Insightful problem solving is a vital part of human thinking, yet very difficult to grasp. Traditionally, insight has been investigated by using a set of established "insight tasks," assuming that insight has taken place if these problems are solved. Instead of assuming that insight takes place during every solution of the 9 Dot, 8 Coin,…

  16. Oligodendrocyte differentiation and implantation : new insights for remyelinating cell therapy

    NARCIS (Netherlands)

    Sher, Falak; Balasubramaniyan, Veerakumar; Boddeke, Erik; Copray, Sjef

    2008-01-01

    Purpose of review Recent research on oligodendrocyte development has yielded new insights on the involvement of morphogens and differentiation factors in oligodendrogenesis. This knowledge has improved strategies to control neural stem cell-derived oligodendrocyte differentiation and functional

  17. Financial insight and behaviour of household consumers in Port ...

    African Journals Online (AJOL)

    Financial insight and behaviour of household consumers in Port Elizabeth. ... improve their money management skills and ensure they eliminate debt, which can be ... Significant relationships between demographical variables and financial ...

  18. SOME INSIGHTS THAT ORALITY-LITERACY STUDIES CAN ...

    African Journals Online (AJOL)

    literacy studies can offer language teachers any insights ... 3.2 Literacy development takes place in a single direction. Another ... and cognitive consequences, is based on the assumption that literacy is .... and as influential with regard to other.

  19. Reading skills, creativity, and insight: exploring the connections.

    Science.gov (United States)

    Mourgues, Catalina V; Preiss, David D; Grigorenko, Elena L

    2014-08-04

    Studies of the relationship between creativity and specific reading disabilities have produced inconclusive results. We explored their relationship in a sample of 259 college students (age range: 17 to 38 years-old) from three Chilean universities. The students were tested on their verbal ability, creativity, and insight. A simple linear regression was performed on the complete sample, and on high- and low-achievement groups that were formed based on reading test scores. We observed a significant correlation in the total sample between outcomes on the verbal ability tasks, and on the creativity and insight tasks (range r =. 152 to r =. 356, ps creativity and insight tasks (range β = .315 to β = .155, ps creative tasks. Instead, higher verbal ability was found to be associated with higher creativity and insight.

  20. the relationship between insight and psychosis in state patients with ...

    African Journals Online (AJOL)

    understanding of problems and personality traits as applied to the self, but also an ... between insight scores and the severity of the mental disorder were measured. ..... namely psychopathology (for instance paranoia, hostility, perplexity and ...

  1. Proteus, New Insights for a New Age (Briefing Charts)

    National Research Council Canada - National Science Library

    Waddell, William O; Kim, Joanne; Smith, Jack

    2004-01-01

    .... The Proteus concept offers a range of new insights that, when used in the planning process, will assist military, intelligence, and industry leaders in their efforts to prepare for future success...

  2. Insight solutions are correct more often than analytic solutions

    Science.gov (United States)

    Salvi, Carola; Bricolo, Emanuela; Kounios, John; Bowden, Edward; Beeman, Mark

    2016-01-01

    How accurate are insights compared to analytical solutions? In four experiments, we investigated how participants’ solving strategies influenced their solution accuracies across different types of problems, including one that was linguistic, one that was visual and two that were mixed visual-linguistic. In each experiment, participants’ self-judged insight solutions were, on average, more accurate than their analytic ones. We hypothesised that insight solutions have superior accuracy because they emerge into consciousness in an all-or-nothing fashion when the unconscious solving process is complete, whereas analytic solutions can be guesses based on conscious, prematurely terminated, processing. This hypothesis is supported by the finding that participants’ analytic solutions included relatively more incorrect responses (i.e., errors of commission) than timeouts (i.e., errors of omission) compared to their insight responses. PMID:27667960

  3. Distributed large-scale dimensional metrology new insights

    CERN Document Server

    Franceschini, Fiorenzo; Maisano, Domenico

    2011-01-01

    Focuses on the latest insights into and challenges of distributed large scale dimensional metrology Enables practitioners to study distributed large scale dimensional metrology independently Includes specific examples of the development of new system prototypes

  4. Insight into nucleon structure from generalized parton distributions

    International Nuclear Information System (INIS)

    J.W. Negele; R.C. Brower; P. Dreher; R. Edwards; G. Fleming; Ph. Hagler; Th. Lippert; A.V.Pochinsky; D.B. Renner; D. Richards; K. Schilling; W. Schroers

    2004-01-01

    The lowest three moments of generalized parton distributions are calculated in full QCD and provide new insight into the behavior of nucleon electromagnetic form factors, the origin of the nucleon spin, and the transverse structure of the nucleon

  5. Training the non-specialist music teacher: insights from a ...

    African Journals Online (AJOL)

    Training the non-specialist music teacher: insights from a Zimbabwean case study. ... music education in primary schools is taught by general classroom teachers, who ... JOURNAL OF THE MUSICAL ARTS IN AFRICA VOLUME 7 2010, 1–15 ...

  6. Astrobiology, Evolution, and Society: Public Engagement Insights

    Science.gov (United States)

    Bertka, C. M.

    2009-12-01

    frequently was “my religious beliefs.” A review of religious identification in this country will be presented in the context of offering insights for public engagement on the topic of evolution, and the contribution that astrobiology could make to encouraging a positive relationship between science and religion. A widespread acceptance of evolution in the United States may require that the scientific community go beyond a simple contrast approach to science and religion and be willing to encourage, and participate in, a program of in-depth and long-term engagement with theologians and religious community leaders. Astrobiology as a discipline is particularly burdened, perhaps blessed, with the responsibility to engage this issue. After all, humanity itself may be inherently defined by the ability we collectively posses to ask “Where did we come from?,” “Are we alone?,” and “Where are we going?”

  7. Insight change in psychosis: Relationship with neurocognition, social cognition, clinical symptoms and phase of illness

    NARCIS (Netherlands)

    P.J. Quee (P.); L. van der Meer (Lisette); L. Krabbendam (Lydia); L. de Haan (Lieuwe); W. Cahn (Wiepke); D. Wiersma (Durk); N.J.M. van Beveren (Nico); G.H.M. Pijnenborg (G. H M); C.L. Mulder (Niels); R. Bruggeman (Richard); A. Aleman (André)

    2014-01-01

    textabstractObjective: Impaired insight is an important and prevalent symptom of psychosis. It remains unclear whether cognitive disturbances hamper improvements in insight. We investigated the neurocognitive, social cognitive, and clinical correlates of changes in insight. Method: One hundred and

  8. Cortical thickness and low insight into symptoms in enduring schizophrenia.

    Science.gov (United States)

    Emami, Seema; Guimond, Synthia; Mallar Chakravarty, M; Lepage, Martin

    2016-01-01

    Poor insight is a common, multidimensional phenomenon in patients with schizophrenia, associated with poorer outcomes and treatment non-adherence. Yet scant research has investigated the neuronal correlates of insight into symptoms (IS), a dimension of insight that may be particularly significant in enduring schizophrenia. Sixty-six patients with enduring schizophrenia (duration >4years) and 33 healthy controls completed MRI scanning and IQ, depression, and anxiety assessments. The Scale to Assess Insight-Expanded (SAI-E) measured insight into patients' four most prominent symptoms and patients were classified into two groups: low IS (0-2; n=33), and high IS (>2; n=33). We evaluated the association between cortical thickness (CT) and insight into symptoms using two methods: (1) a between-patients region-of-interest analysis in the insula, superior temporal gyrus (STG) and frontal lobe; and (2) a whole-brain exploratory regression between patient and controls. Brain regions were segmented using a neuroanatomical atlas and vertex-wise CT analyses were conducted with CIVET, covaried for age and sex. ROI analysis revealed thinner insula cortex in patients with low IS (pinsight-related differences in CT that has been previously unexplored in enduring schizophrenia. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. The “Insight Paradox” in Schizophrenia: Magnitude, Moderators and Mediators of the Association Between Insight and Depression

    Science.gov (United States)

    Belvederi Murri, Martino; Amore, Mario; Calcagno, Pietro; Respino, Matteo; Marozzi, Valentina; Masotti, Mattia; Bugliani, Michele; Innamorati, Marco; Pompili, Maurizio; Galderisi, Silvana; Maj, Mario

    2016-01-01

    The so-called “insight paradox” posits that among patients with schizophrenia higher levels of insight are associated with increased levels of depression. Although different studies examined this issue, only few took in account potential confounders or factors that could influence this association. In a sample of clinically stable patients with schizophrenia, insight and depression were evaluated using the Scale to assess Unawareness of Mental Disorder and the Calgary Depression Scale for Schizophrenia. Other rating scales were used to assess the severity of psychotic symptoms, extrapyramidal symptoms, hopelessness, internalized stigma, self-esteem, and service engagement. Regression models were used to estimate the magnitude of the association between insight and depression while accounting for the role of confounders. Putative psychological and sociodemographic factors that could act as mediators and moderators were examined using the PROCESS macro. By accounting for the role of confounding factors, the strength of the association between insight into symptoms and depression increased from 13% to 25% explained covariance. Patients with lower socioeconomic status (F = 8.5, P = .04), more severe illness (F = 4.8, P = .03) and lower levels of service engagement (F = 4.7, P = .03) displayed the strongest association between insight and depression. Lastly, hopelessness, internalized stigma and perceived discrimination acted as significant mediators. The relationship between insight and depression should be considered a well established phenomenon among patients with schizophrenia: it seems stronger than previously reported especially among patients with lower socioeconomic status, severe illness and poor engagement with services. These findings may have relevant implications for the promotion of insight among patients with schizophrenia. PMID:27069064

  10. Insight, grey matter and cognitive function in first-onset psychosis.

    LENUS (Irish Health Repository)

    Morgan, Kevin D

    2010-08-01

    Several studies have suggested that neuropsychological and structural brain deficits are implicated in poor insight. Few insight studies however have combined neurocognitive and structural neuroanatomical measures.

  11. Insight and analysis problem solving in microbes to machines.

    Science.gov (United States)

    Clark, Kevin B

    2015-11-01

    A key feature for obtaining solutions to difficult problems, insight is oftentimes vaguely regarded as a special discontinuous intellectual process and/or a cognitive restructuring of problem representation or goal approach. However, this nearly century-old state of art devised by the Gestalt tradition to explain the non-analytical or non-trial-and-error, goal-seeking aptitude of primate mentality tends to neglect problem-solving capabilities of lower animal phyla, Kingdoms other than Animalia, and advancing smart computational technologies built from biological, artificial, and composite media. Attempting to provide an inclusive, precise definition of insight, two major criteria of insight, discontinuous processing and problem restructuring, are here reframed using terminology and statistical mechanical properties of computational complexity classes. Discontinuous processing becomes abrupt state transitions in algorithmic/heuristic outcomes or in types of algorithms/heuristics executed by agents using classical and/or quantum computational models. And problem restructuring becomes combinatorial reorganization of resources, problem-type substitution, and/or exchange of computational models. With insight bounded by computational complexity, humans, ciliated protozoa, and complex technological networks, for example, show insight when restructuring time requirements, combinatorial complexity, and problem type to solve polynomial and nondeterministic polynomial decision problems. Similar effects are expected from other problem types, supporting the idea that insight might be an epiphenomenon of analytical problem solving and consequently a larger information processing framework. Thus, this computational complexity definition of insight improves the power, external and internal validity, and reliability of operational parameters with which to classify, investigate, and produce the phenomenon for computational agents ranging from microbes to man-made devices. Copyright

  12. Psychophysiological prediction of choice: relevance to insight and drug addiction

    Science.gov (United States)

    Moeller, Scott J.; Hajcak, Greg; Parvaz, Muhammad A.; Dunning, Jonathan P.; Volkow, Nora D.

    2012-01-01

    An important goal of addiction research and treatment is to predict behavioural responses to drug-related stimuli. This goal is especially important for patients with impaired insight, which can interfere with therapeutic interventions and potentially invalidate self-report questionnaires. This research tested (i) whether event-related potentials, specifically the late positive potential, predict choice to view cocaine images in cocaine addiction; and (ii) whether such behaviour prediction differs by insight (operationalized in this study as self-awareness of image choice). Fifty-nine cocaine abusers and 32 healthy controls provided data for the following laboratory components that were completed in a fixed-sequence (to establish prediction): (i) event-related potential recordings while passively viewing pleasant, unpleasant, neutral and cocaine images, during which early (400–1000 ms) and late (1000–2000 ms) window late positive potentials were collected; (ii) self-reported arousal ratings for each picture; and (iii) two previously validated tasks: one to assess choice for viewing these same images, and the other to group cocaine abusers by insight. Results showed that pleasant-related late positive potentials and arousal ratings predicted pleasant choice (the choice to view pleasant pictures) in all subjects, validating the method. In the cocaine abusers, the predictive ability of the late positive potentials and arousal ratings depended on insight. Cocaine-related late positive potentials better predicted cocaine image choice in cocaine abusers with impaired insight. Another emotion-relevant event-related potential component (the early posterior negativity) did not show these results, indicating specificity of the late positive potential. In contrast, arousal ratings better predicted respective cocaine image choice (and actual cocaine use severity) in cocaine abusers with intact insight. Taken together, the late positive potential could serve as a biomarker

  13. The Neurocircuitry of Impaired Insight in Drug Addiction

    Science.gov (United States)

    Goldstein, Rita Z.; Craig, A. D. (Bud); Bechara, Antoine; Garavan, Hugh; Childress, Anna Rose; Paulus, Martin P.; Volkow, Nora D.

    2010-01-01

    More than 80% of addicted individuals fail to seek treatment, which might reflect impairments in recognition of severity of disorder. Considered by some as intentional deception, such `denial' might instead reflect dysfunction of brain networks subserving insight and selfawareness. Here we review the scant literature on insight in addiction and integrate this perspective with the role of: (i) the insula in interoception, self-awareness and drug craving; (ii) the anterior cingulate in behavioral monitoring and response selection (relevant to disadvantageous choices in addiction); (iii) the dorsal striatum in automatic habit formation; and (iv) drug related stimuli that predict emotional behavior in addicted individuals, even without conscious awareness. We discuss implications for clinical treatment including the design of interventions to improve insight into illness severity in addiction. PMID:19716751

  14. The Neurocircuitry of Impaired Insight in Drug Addiction

    Energy Technology Data Exchange (ETDEWEB)

    Goldstein, R.Z.; Craig, A.D.; Bechara, A.; Garavan, H.; Childress, A.R.; Paulus, M.P.; Volkow, N.D.

    2009-08-27

    More than 80% of addicted individuals fail to seek treatment, which might reflect impairments in recognition of severity of disorder. Considered by some as intentional deception, such 'denial' might instead reflect dysfunction of brain networks subserving insight and self-awareness. Here we review the scant literature on insight in addiction and integrate this perspective with the role of: (i) the insula in interoception, self-awareness and drug craving; (ii) the anterior cingulate in behavioral monitoring and response selection (relevant to disadvantageous choices in addiction); (iii) the dorsal striatum in automatic habit formation; and (iv) drug-related stimuli that predict emotional behavior in addicted individuals, even without conscious awareness. We discuss implications for clinical treatment including the design of interventions to improve insight into illness severity in addiction.

  15. Data smart using data science to transform information into insight

    CERN Document Server

    Foreman, John W

    2013-01-01

    Data Science gets thrown around in the press like it's magic. Major retailers are predicting everything from when their customers are pregnant to when they want a new pair of Chuck Taylors. It's a brave new world where seemingly meaningless data can be transformed into valuable insight to drive smart business decisions. But how does one exactly do data science? Do you have to hire one of these priests of the dark arts, the ""data scientist,"" to extract this gold from your data? Nope. Data science is little more than using straight-forward steps to process raw data into actionable insight.

  16. Consumer Insight as Competitive Advantage Using Big Data and Analytics

    Directory of Open Access Journals (Sweden)

    Adnan Veysel Ertemel

    2015-12-01

    Full Text Available Digital revolution serves as a competitive advantage to businesses that are able to analyze consumer behavior in order to gain insights for their strategic advantage. After the advent of Internet, the past two decades witnessed generation of vast amount of business data. The amount of data is so huge that traditional database management system approaches falls short of managing and analyzing this data. This paper explores the characteristics of this phenomenon called Big Data together with Analytics as a tool for marketers to gain insights about consumer behavior and hence provide competitive advantage to the businesses. It also discusses some best practices as case studies.

  17. Personal aggrandizement: an insight into Ben Enwonwu's privilege ...

    African Journals Online (AJOL)

    This paper titled Personal Aggrandizement: An Insight into Ben Enwonwu's Privilege Position in the Evolution of Nigerian Art, looks at the first trained artists. How the artists were classified by their styles either in the naturalistic, the abstract or the expressive imageries. The study examines and compares the contributions of ...

  18. Silicon Graphics' IRIS InSight: An SGML Success Story.

    Science.gov (United States)

    Glushko, Robert J.; Kershner, Ken

    1993-01-01

    Offers a case history of the development of the Silicon Graphics "IRIS InSight" system, a system for viewing on-line documentation using Standard Generalized Markup Language. Notes that SGML's explicit encoding of structure and separation of structure and presentation make possible structure-based search, alternative structural views of…

  19. Financing sustainability: insights for investors, corporate executives, and policymakers

    NARCIS (Netherlands)

    Kerste, M.; Rosenboom, N.; Sikken, B.J.; Weda, J.

    2011-01-01

    Sustainability thinking is rapidly gaining traction. It o­ffers an inspiring vision for the future of the world and provides significant business and investment opportunities. Based on insights from over 300 empirical studies, this book explores the possibilities in the field of renewable energy

  20. The Beta Israel: Return to the source? | Zegeye | Africa Insight

    African Journals Online (AJOL)

    Even after more than two decades, over 70 000 Ethiopian Jews - the Beta Israel - have still not been fully accepted in Israel, in danger of becoming an ethnically defined 'under-class'. The potential of Beta Israel contributions to both Israeli and Ethiopian society should be recognised. Africa Insight Vol.34(1) 2004: 69-75 ...

  1. Gaining insight into the effects : the supplier perspective

    NARCIS (Netherlands)

    Michiel Steeman; Christiaan de Goeij; Paulien de Graaf-Muller

    2016-01-01

    In this paper we discuss what suppliers can do to get insight into the effects of Reverse Factoring (RF), currently the most used form of Supply Chain Finance (SCF). Even though the usage of RF is increasing, empirical evidence is scarce, especially from the point of view of suppliers.

  2. Hydrothermal Processes in the Archean - New Insights from Imaging Spectroscopy

    NARCIS (Netherlands)

    Ruitenbeek, F.J.A. van

    2007-01-01

    The aim of this research was to gain new insights in fossil hydrothermal systems using airborne imaging spectroscopy. Fossil submarine hydrothermal systems in Archean greenstone belts and other geologic terranes are important because of their relationship with volcanic massive sulfide (VMS) mineral

  3. Geometric Insight into Scalar Combination of Linear Equations

    Indian Academy of Sciences (India)

    ... Journals; Resonance – Journal of Science Education; Volume 14; Issue 11. Geometric Insight into Scalar Combination of Linear Equations. Ranjit Konkar. Classroom Volume 14 Issue 11 November 2009 pp 1092-1097 ... Keywords. Linear algebra; linear dependence; linear combination; family of lines; family of planes.

  4. Insights into the feeding ecology of the Seychelles Black Parrot ...

    African Journals Online (AJOL)

    Insights into the feeding ecology of the Seychelles Black Parrot Coracopsis barklyi using two monitoring approaches. ... The incidental method is not suitable for quantitative conclusions but complements the transect method, providing information about rarely occurring feeding events. Keywords: Coracopsis barklyi, feeding ...

  5. Shaping Social Justice Leadership: Insights of Women Educators Worldwide

    Science.gov (United States)

    Lyman, Linda L.; Strachan, Jane; Lazaridou, Angeliki

    2012-01-01

    "Shaping Social Justice Leadership: Insights of Women Educators Worldwide" contains evocative portraits of twenty-three women educators and leaders from around the world whose actions are shaping social justice leadership. Woven from words of their own narratives, the women's voices lift off the page into readers' hearts and minds to inspire and…

  6. The Domain-Specificity of Creativity: Insights from New Phenomenology

    Science.gov (United States)

    Julmi, Christian; Scherm, Ewald

    2015-01-01

    The question of the domain-specificity of creativity represents one of the key questions in creativity research. This article contributes to the discussion by applying insights from "new phenomenology," which is a phenomenological movement from Germany initiated by philosopher Hermann Schmitz. The findings of new phenomenology suggest…

  7. Financial insight and behaviour of household consumers in Port ...

    African Journals Online (AJOL)

    of this study was to investigate the financial insight and behaviour of household .... investigated the influence of quantitative literacy and material values on personal financial behaviour. .... Analysis of variance (ANOVA) was also conducted to determine ..... 'The financial literacy of micro enterprises in South Africa', Journal of.

  8. Insight and illness perception in Mexican patients with psychosis

    Directory of Open Access Journals (Sweden)

    Lizzette Gómez-de-Regil

    2015-03-01

    Conclusions: The study not only replicates the significant association on insight and illness perception with clinical outcome, but shows how their patterns of interactions are different, reinforcing the idea that they are two distinct factors worthy of being habitually acknowledged in research and clinical practice.

  9. Translation in Language Teaching: Insights from Professional Translator Training

    Science.gov (United States)

    Carreres, Angeles; Noriega-Sanchez, Maria

    2011-01-01

    The past three decades have seen vast changes in attitudes towards translation, both as an academic discipline and as a profession. The insights we have gained in recent years, in particular in the area of professional translator training, call for a reassessment of the role of translation in language teaching. Drawing on research and practices in…

  10. Insights into translation and the original text: Thomas Mofolo's Chaka

    African Journals Online (AJOL)

    This paper aims to explore the strategies applied during the translation of chosen passages from the original Sesotho text of Chaka by Thomas Mofolo into English. Insights expressed here originate from participation in the translation workshops during the conference on “Translating Mofolo”. Different stages of the ...

  11. Selecting Solar. Insights into Residential Photovoltaic (PV) Quote Variation

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, Carolyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-10-01

    This analysis leverages available data from EnergySage, an online solar marketplace, to offer the first data-driven characterization of quote variation faced by prospective PV customers, lending early insight into the decisions customers face once they have initial buy-in.

  12. Behavioral Public Administration : Combining Insights from Public Administration and Psychology

    NARCIS (Netherlands)

    Grimmelikhuijsen, S.G.|info:eu-repo/dai/nl/313875405; Jilke, Sebastian; Leth Olsen, Asmus; Tummers, L.G.|info:eu-repo/dai/nl/341028274

    2016-01-01

    Behavioral public administration is the analysis of public administration from the micro-perspective of individual behavior and attitudes by drawing upon insights from psychology on behavior of individuals and groups. We discuss how scholars in public administration currently draw on theories and

  13. Sex Change in Clownfish: Molecular Insights from Transcriptome Analysis

    KAUST Repository

    Casas, Laura; Saborido-Rey, Fran; Ryu, Tae Woo; Michell, Craig; Ravasi, Timothy; Irigoien, Xabier

    2016-01-01

    steroidogenic machinery during sex change in clownfish, with the aromatase gene playing a central role, both in the brain and the gonad. This work constitutes the first genome-wide study in a social sex-changing species and provides insights into the genetic

  14. Can matter and spirit be mediated through language? Some insights ...

    African Journals Online (AJOL)

    Neuroscience utilises insights from the theory of complex systems to attempt to understand how perception, thought and self-awareness can arise as a consequence of the complex system that is the brain. However, already at the height of the Enlightenment, a contemporary and critic of Immanuel Kant, Johann Georg ...

  15. The Empty Shops Project: Developing Rural Students' Sociological Insight

    Science.gov (United States)

    Willis, Evan; Burns, Edgar

    2011-01-01

    An informal research project with high local relevance was developed for a first-year sociology course at an Australian rural university campus. The project developed students' sociological insight by challenging them to investigate "truths" about their own region, rather than immediately pushing them to comprehend new and different…

  16. The South African wine industry: Insights survey 2013

    CSIR Research Space (South Africa)

    Blok, T

    2013-09-01

    Full Text Available PwC’s 2013 South African wine industry insights survey explores some of the issues facing local wine businesses, specifically those evident from the financial results of the 2012 harvest, human resource management practices in the industry and wine...

  17. Clinical insights into use of apomorphine in Parkinson's disease

    DEFF Research Database (Denmark)

    Henriksen, Tove

    2014-01-01

    is achieved a significant reduction of pre-existing levodopainduced dyskinesias is seen. The aim of this review is to give practical insight into apomorphine treatment, highlighting side effects, and complications and device-related problems are discussed with advice on how to prevent or handle these, should...

  18. Use of Human Reliability Insights to Improve Decision-Making

    International Nuclear Information System (INIS)

    Julius, J. A.; Moieni, P.; Grobbelaar, J.; Kohlhepp, K.

    2016-01-01

    This paper describes the use of insights obtained during the development and application of human reliability analysis (HRA) as part of a probabilistic risk assessment (PRA) to support decision-making, including improvements to operations, training, and safety culture. Insights have been gained from the development and application of HRA as part of a PRA for nuclear power plants in the USA, Europe and Asia over the last two decades. These models consist of Level 1 and Level 2 PRA models of internal and external events, during full power and shutdown modes of plant operation. These insights include the use of human factors information to improve the qualitative portion of the HRA. The subsequent quantification in the HRA effectively prioritises the contributors to the unreliability of operator actions, and the process facilitates the identification of the factors that are important to the success of the operator actions. Additionally, the tools and techniques also allow for the evaluation of key assumptions and sources of uncertainty. The end results have been used to effectively support decision-making for day-to-day plant operations as well as licensing issues. HRA results have been used to provide feedback and improvements to plant procedures, operator training and other areas contributing the plant safety culture. Examples of the types of insights are presented in this paper. (author)

  19. Molecular Electronics: Insight from First-Principles Transport Simulations

    DEFF Research Database (Denmark)

    Paulsson, Magnus; Frederiksen, Thomas; Brandbyge, Mads

    2010-01-01

    Conduction properties of nanoscale contacts can be studied using first-principles simulations. Such calculations give insight into details behind the conductance that is not readily available in experiments. For example, we may learn how the bonding conditions of a molecule to the electrodes affect...

  20. Facilitate insight by non-invasive brain stimulation.

    Directory of Open Access Journals (Sweden)

    Richard P Chi

    Full Text Available Our experiences can blind us. Once we have learned to solve problems by one method, we often have difficulties in generating solutions involving a different kind of insight. Yet there is evidence that people with brain lesions are sometimes more resistant to this so-called mental set effect. This inspired us to investigate whether the mental set effect can be reduced by non-invasive brain stimulation. 60 healthy right-handed participants were asked to take an insight problem solving task while receiving transcranial direct current stimulation (tDCS to the anterior temporal lobes (ATL. Only 20% of participants solved an insight problem with sham stimulation (control, whereas 3 times as many participants did so (p = 0.011 with cathodal stimulation (decreased excitability of the left ATL together with anodal stimulation (increased excitability of the right ATL. We found hemispheric differences in that a stimulation montage involving the opposite polarities did not facilitate performance. Our findings are consistent with the theory that inhibition to the left ATL can lead to a cognitive style that is less influenced by mental templates and that the right ATL may be associated with insight or novel meaning. Further studies including neurophysiological imaging are needed to elucidate the specific mechanisms leading to the enhancement.

  1. Genetic and biochemical evidences reveal novel insights into the ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 4. Genetic and biochemical evidences reveal novel insights into the mechanism underlying Saccharomyces cerevisiae Sae2-mediated abrogation of DNA replication stress. INDRAJEET GHODKE K MUNIYAPPA. ARTICLE Volume 41 Issue 4 December 2016 pp ...

  2. Group Insight Versus Group Desensitization in Treating Speech Anxiety

    Science.gov (United States)

    Meichenbaum, Donald H.; And Others

    1971-01-01

    Results of this study indicated that the insight group was as effective as the desensitization group in significantly reducing speech anxiety over control group levels as assessed by behavioral, cognitive, and self-report measures given immediately after posttreatment and later at a three-month follow-up. (Author)

  3. Accounting choices of controllers : An insight into controller deliberations

    NARCIS (Netherlands)

    de Groot, Therèse

    2015-01-01

    This doctoral thesis provides insights into the accounting choice process of business controllers. The main contribution is a new approach in analyzing financial accounting choices, using an interpretive methodology. Moreover, the overall framework of analysis developed in this thesis can help

  4. Administrator Responses to Financial Incentives: Insights from a TIF Program

    Science.gov (United States)

    King Rice, Jennifer; Malen, Betty; Jackson, Cara; Hoyer, Kathleen Mulvaney

    2017-01-01

    This article provides evidence and generates insights about the power of financial rewards to motivate school administrators and the design features that influence their motivational potency. The multi-year mixed-methods study is grounded in expectancy and goal setting theories that suggest (a) awards must be salient and sizable enough to appeal…

  5. The relationship between insight and subjective experience in schizophrenia

    Directory of Open Access Journals (Sweden)

    Kako Y

    2014-07-01

    Full Text Available Yuki Kako, Koki Ito, Naoki Hashimoto, Kuniyoshi Toyoshima, Yusuke Shimizu, Nobuyuki Mitsui, Yutaka Fujii, Teruaki Tanaka, Ichiro Kusumi Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan Objectives: To examine the relationship between level of insight and various subjective experiences for patients with schizophrenia.Materials and methods: Seventy-four patients with schizophrenia who were discharged from our hospital were evaluated. The level of insight into their illness and various subjective experiences were evaluated at discharge. We used the Scale to Assess Unawareness of Mental Disorder (SUMD for evaluation of insight. In addition, five different rating scales were used to evaluate subjective experiences: Subjective Experience of Deficits in Schizophrenia (SEDS, Subjective Well-being under Neuroleptic drug treatment Short form (SWNS, Schizophrenia Quality of Life Scale (SQLS, Beck Depression Inventory (BDI, and the Drug Attitude Inventory (DAI-30.Results: The SWNS and the scores for awareness of mental disorder and awareness of the social consequences of mental disorder on SUMD showed a weak positive correlation. The DAI-30 showed a significant negative correlation with most general items on SUMD and a negative correlation between the subscale scores for the awareness and attribution of past symptoms. SEDS, SWNS, SQLS, and the BDI significantly correlated with the subscale scores for awareness of current symptoms on SUMD, and weakly correlated with the subscale scores for attribution of current negative symptoms.Conclusion: Awareness of subjective distress was related to awareness of having a mental disorder. Feeling subjective distress was related to awareness of current symptoms, as well as to the ability to attribute current negative symptoms to a mental disorder. Positive attitudes toward medication correlated with better general insight into the illness. Keywords: schizophrenia, insight

  6. Insightful practice: a reliable measure for medical revalidation

    Science.gov (United States)

    Guthrie, Bruce; Sullivan, Frank M; Mercer, Stewart W; Russell, Andrew; Bruce, David A

    2012-01-01

    Background Medical revalidation decisions need to be reliable if they are to reassure on the quality and safety of professional practice. This study tested an innovative method in which general practitioners (GPs) were assessed on their reflection and response to a set of externally specified feedback. Setting and participants 60 GPs and 12 GP appraisers in the Tayside region of Scotland, UK. Methods A feedback dataset was specified as (1) GP-specific data collected by GPs themselves (patient and colleague opinion; open book self-evaluated knowledge test; complaints) and (2) Externally collected practice-level data provided to GPs (clinical quality and prescribing safety). GPs' perceptions of whether the feedback covered UK General Medical Council specified attributes of a ‘good doctor’ were examined using a mapping exercise. GPs' professionalism was examined in terms of appraiser assessment of GPs' level of insightful practice, defined as: engagement with, insight into and appropriate action on feedback data. The reliability of assessment of insightful practice and subsequent recommendations on GPs' revalidation by face-to-face and anonymous assessors were investigated using Generalisability G-theory. Main outcome measures Coverage of General Medical Council attributes by specified feedback and reliability of assessor recommendations on doctors' suitability for revalidation. Results Face-to-face assessment proved unreliable. Anonymous global assessment by three appraisers of insightful practice was highly reliable (G=0.85), as were revalidation decisions using four anonymous assessors (G=0.83). Conclusions Unlike face-to-face appraisal, anonymous assessment of insightful practice offers a valid and reliable method to decide GP revalidation. Further validity studies are needed. PMID:22653078

  7. Mentalization, insightfulness, and therapeutic action. The importance of mental organization.

    Science.gov (United States)

    Sugarman, Alan

    2006-08-01

    Continuing debates over the relative importance of the role of interpretation leading to insight versus the relationship with the analyst as contributing to structural change are based on traditional definitions of insight as gaining knowledge of unconscious content. This definition inevitably privileges verbal interpretation as self-knowledge becomes equated with understanding the contents of the mind. It is suggested that a way out of this debate is to redefine insight as a process, one that is called insightfulness. This term builds on concepts such as mentalization, or theory of mind, and suggests that patients present with difficulties being able to fully mentalize. Awareness of repudiated content will usually accompany the attainment of insightfulness. But the point of insightfulness is to regain access to inhibited or repudiated mentalization, not to specific content, per se. Emphasizing the process of insightfulness integrates the importance of the relationship with the analyst with the facilitation of insightfulness. A variety of interventions help patients gain the capacity to reflect upon and become aware of the intricate workings of their minds, of which verbal interpretation is only one. For example, often it seems less important to focus on a particular conflict than to show interest in our patients' minds. Furthermore, analysands develop insightfulness by becoming interested in and observing our minds in action. Because the mind originates in bodily experience, mental functioning will always fluctuate between action modes of experiencing and expressing and verbal, symbolic modes. The analyst's role becomes making the patient aware of regressions to action modes, understanding the reasons for doing so, and subordinating this tendency to the verbal, symbolic mode. All mental functions work better and facilitate greater self-regulation when they work in abstract, symbolic ways. Psychopathology can be understood as failing to develop or losing the

  8. Assessing cognitive insight in nonpsychiatric individuals and outpatients with schizophrenia in Taiwan: an investigation using the Beck Cognitive Insight Scale

    Directory of Open Access Journals (Sweden)

    Lu Chien-Wen

    2011-10-01

    Full Text Available Abstract Background The Beck Cognitive Insight Scale (BCIS was designed for the assessment of the cognitive processes involved in self-reflection and the ability to modify erroneous beliefs and misinterpretations. Studies investigating the factor structure of the BCIS have indicated a two-factor model in the psychotic population. The factor structure of the BCIS, however, has not received much consideration in the nonpsychiatric population. The present study examined the factor structure and validity of the BCIS and compared its scores between nonpsychiatric individuals and outpatients with psychosis. Method The Taiwanese version of the BCIS was administered to 507 nonpsychiatric individuals and 118 outpatients with schizophrenia. The psychometric properties of the BCIS were examined through the following analyses: exploratory and confirmatory factor analyses, reliability, correlation analyses, and discriminative validity. Results The BCIS showed adequate internal consistency and stability over time. Exploratory and confirmatory factor analyses on the 15-item measure indicated a two-factor solution that supported the two dimensions of the Taiwanese BCIS, which was also observed with the original BCIS. Following the construct validation, we obtained a composite index (self-reflectiveness minus self-certainty of the Taiwanese BCIS that reflected cognitive insight. Consistent with previous studies, our results indicated that psychosis is associated with low self-reflectiveness and high self-certainty, which possibly reflect lower cognitive insight. Our results also showed that better cognitive insight is related to worse depression in patients with schizophrenia spectrum disorders, but not in nonpsychiatric individuals. The receiver operating characteristic (ROC analyses revealed that the area under the curve (AUC was 0.731. A composite index of 3 was a good limit, with a sensitivity of 87% and a specificity of 51%. Conclusion The BCIS proved to be

  9. Insights on the poster preparation and presentation process.

    Science.gov (United States)

    Moore, L W; Augspurger, P; King, M O; Proffitt, C

    2001-05-01

    Dissemination of research findings and effective clinical innovations is key to the growth and development of the nursing profession. Several avenues exist for the dissemination of information. One forum for communication that has gained increased recognition over the past decade is the poster presentation. Poster presentations are often a significant part of regional, national, and international nursing conferences. Although posters are frequently used to disseminate information to the nursing community, little is reported about actual poster presenters' experiences with preparation and presentation of their posters. The purpose of this article is to present insights derived from information shared by poster presenters regarding the poster preparation and presentation process. Such insights derived from the personal experiences of poster presenters may assist others to efficiently and effectively prepare and present scholarly posters that disseminate information to the nursing community. Copyright 2001 by W.B. Saunders Company

  10. Key insights for the future of urban ecosystem services research

    Directory of Open Access Journals (Sweden)

    Peleg Kremer

    2016-06-01

    Full Text Available Understanding the dynamics of urban ecosystem services is a necessary requirement for adequate planning, management, and governance of urban green infrastructure. Through the three-year Urban Biodiversity and Ecosystem Services (URBES research project, we conducted case study and comparative research on urban biodiversity and ecosystem services across seven cities in Europe and the United States. Reviewing > 50 peer-reviewed publications from the project, we present and discuss seven key insights that reflect cumulative findings from the project as well as the state-of-the-art knowledge in urban ecosystem services research. The insights from our review indicate that cross-sectoral, multiscale, interdisciplinary research is beginning to provide a solid scientific foundation for applying the ecosystem services framework in urban areas and land management. Our review offers a foundation for seeking novel, nature-based solutions to emerging urban challenges such as wicked environmental change issues.

  11. Perioperative leadership: managing change with insights, priorities, and tools.

    Science.gov (United States)

    Taylor, David L

    2014-07-01

    The personal leadership of the perioperative director is a critical factor in the success of any change management initiative. This article presents an approach to perioperative nursing leadership that addresses obstacles that prevent surgical departments from achieving high performance in clinical and financial outcomes. This leadership approach consists of specific insights, priorities, and tools: key insights include self-understanding of personal barriers to leadership and accuracy at understanding economic and strategic considerations related to the OR environment; key priorities include creating a customer-centered organization, focusing on process improvement, and concentrating on culture change; and key tools include using techniques (e.g., direct engagement, collaborative leadership) to align surgical organizations with leadership priorities and mitigate specific perioperative management risks. Included in this article is a leadership development plan for perioperative directors. Copyright © 2014 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  12. Psychological insights in Shakespeare's final play, The Two Noble Kinsmen.

    Science.gov (United States)

    Mahon, E J

    2001-01-01

    Shakespeare's final play, The Two Noble Kinsmen, contains profound psychological insights. Like all of Shakespeare's reworkings of old material, the result is not merely a variation on a theme but a psychological statement in and of itself, which respects and revisits the past even as it presents a new and original statement. In this paper I argue that the transformation of the Chaucerian into the Shakespearean has a premonition of the Freudian in it also: Shakespeare not only delivers insights on development and sexuality, he anticipates an important Freudian concept in his introduction of the theme of the jailer's daughter whose "love-sickness" requires on understanding of transference before sense can be made of it!

  13. Numerical Experiments Providing New Insights into Plasma Focus Fusion Devices

    Directory of Open Access Journals (Sweden)

    Sing Lee

    2010-04-01

    Full Text Available Recent extensive and systematic numerical experiments have uncovered new insights into plasma focus fusion devices including the following: (1 a plasma current limitation effect, as device static inductance is reduced towards very small values; (2 scaling laws of neutron yield and soft x-ray yield as functions of storage energies and currents; (3 a global scaling law for neutron yield as a function of storage energy combining experimental and numerical data showing that scaling deterioration has probably been interpreted as neutron ‘saturation’; and (4 a fundamental cause of neutron ‘saturation’. The ground-breaking insights thus gained may completely change the directions of plasma focus fusion research.

  14. Exploring the reducing role of boron: added insights from theory.

    Science.gov (United States)

    Dangat, Yuvraj; Vanka, Kumar

    2016-04-14

    Carbon-carbon coupling in CO molecules is a challenging proposition, and very few main group complexes have been shown to effect this process. A recently reported triply bonded diboryne system (1) is notable for coupling four CO molecules to produce a (bis)boralactone species. The current full quantum chemical computational investigation with density functional theory (DFT) provides important insights into the nature of the CO coupling process by triply bonded diboryne systems. The complete reaction pathway leading to the formation of the (bis)boralactone has been determined. Factors that make this system so successful in coupling CO groups have been elucidated, and pertinent issues, such as why the coupling process stops after four CO additions, have been explored. Also, importantly, insights have been gained through the natural bond orbital (NBO) analysis into how the back-donation from diboryne activates CO.

  15. Genomic Insights into Growth and Its Disorders: An Update

    Science.gov (United States)

    de Bruin, Christiaan; Dauber, Andrew

    2016-01-01

    Purpose of review To provide an update of the most striking new developments in the field of growth genetics over the past 12 months Recent findings A number of large genome-wide association studies have identified new genetic loci and pathways associated to human growth and adult height as well as related traits and comorbidities. New genetic etiologies of primordial dwarfism and several short stature syndromes have been elucidated. Moreover, a breakthrough finding of Xq26 microduplications as a cause of pituitary gigantism was made. Several new developments in imprinted growth-related genes (including the first human mutation in IGF-II) and novel insights into the epigenetic regulation of growth have been reported. Summary Genomic investigations continue to provide new insights into the genetic basis of human growth as well as its disorders. PMID:26702851

  16. Insights into Modern Human Prehistory Using Ancient Genomes.

    Science.gov (United States)

    Yang, Melinda A; Fu, Qiaomei

    2018-03-01

    The genetic relationship of past modern humans to today's populations and each other was largely unknown until recently, when advances in ancient DNA sequencing allowed for unprecedented analysis of the genomes of these early people. These ancient genomes reveal new insights into human prehistory not always observed studying present-day populations, including greater details on the genetic diversity, population structure, and gene flow that characterized past human populations, particularly in early Eurasia, as well as increased insight on the relationship between archaic and modern humans. Here, we review genetic studies on ∼45000- to 7500-year-old individuals associated with mainly preagricultural cultures found in Eurasia, the Americas, and Africa. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Reintegration upon return: insights from Ecuadorian returnees from Spain

    OpenAIRE

    Mercier, Marion; David, Anda; Mahia, Ramón; De Arce, Rafael

    2016-01-01

    Using the ECM2 survey data on Ecuadorian migrants returning from Spain, we investigate the determinants of reintegration upon return. We study how the migration experience, but also the before- and after-migration characteristics, correlate with migrants’ outcomes upon return. We adopt a broad conception of reintegration, considering jointly labour market-related outcomes that proxy for structural reintegration and subjective indicators that provide insights on sociocultural reintegration. Th...

  18. Insights into Motivating Internet Users towards Internet Banking

    OpenAIRE

    J. Ramola Premalatha

    2016-01-01

    Internet banking has evolved from helping customers meet their basic banking needs to meeting their sophisticated needs. In recent years, the number of internet banking users has been increasing exponentially. As customers get more and more educated, getting insight about internet banking has become a primary area of concern for all leading banks in India. Hence, the study is made to analyse the perception of customers specifically who are computer literate, in a semi-urban area about interne...

  19. Consumer Insight as Competitive Advantage Using Big Data and Analytics

    OpenAIRE

    Adnan Veysel Ertemel

    2015-01-01

    Digital revolution serves as a competitive advantage to businesses that are able to analyze consumer behavior in order to gain insights for their strategic advantage. After the advent of Internet, the past two decades witnessed generation of vast amount of business data. The amount of data is so huge that traditional database management system approaches falls short of managing and analyzing this data. This paper explores the characteristics of this phenomenon called Big Data together with An...

  20. Hip fracture discrimination by the Achilles Insight QUS imaging device

    International Nuclear Information System (INIS)

    Damilakis, John; Papadokostakis, George; Perisinakis, Kostas; Maris, Thomas G.; Karantanas, Apostolos H.

    2007-01-01

    The importance of osteoporosis as a major health problem is well recognized. Its major clinical manifestation is low energy fractures. Considerable effort has been directed towards search of noninvasive methods for assessing osteoporotic fracture risk. The aim of this study was to evaluate the ability of quantitative ultrasound (QUS) variables measured by a new heel QUS imaging device to discriminate between postmenopausal women with and without hip fracture. The subjects included 30 postmenopausal female patients with hip fracture and 30 age-matched healthy women. Measurements were acquired using the Achilles Insight QUS imaging device. Bone mineral density (BMD) measurements were carried out using the Lunar Prodigy DXA scanner. Achilles Insight provides images of the heel bone and measures broadband ultrasound attenuation (BUA) and speed of sound (SOS) values in a circular region of interest. A third QUS variable, the stiffness index (SI) was also determined. The short-term precision for healthy subjects was 2.05%, 0.17% and 1.91% for BUA, SOS and SI, respectively. Corresponding values for patients with fractures were 1.80%, 0.16% and 2.04%. All QUS variables measured using the Achilles Insight were significant discriminators of hip fractures (area under ROC curve = 0.77, 0.74 and 0.77 for BUA, SOS and SI, respectively). BMD measurements of the hip had the greatest discriminatory ability (area under ROC curve = 0.88). Statistically significant differences were found between the area under the ROC curve of BMD and the corresponding curves of the QUS variables (P < 0.05 for each of the three comparisons). QUS variables measured by Achilles Insight can be expected to be useful as indicators of the risk of hip fracture in postmenopausal women

  1. Cyber Conflict Between Taiwan and China; Strategic Insights, Spring 2011

    OpenAIRE

    Chang, Yao-chung

    2011-01-01

    This article appeared in Strategic Insights, Spring 2011 The Republic of China (Taiwan hereafter) and the People’s Republic of China (China hereafter) are two particularly attractive targets for internet hackers. Reports have found that, compared to other countries in the Asia and Pacific regions, China and Taiwan rank as the top two countries in terms of malicious computer activity. Reports have also shown that most hacking into Taiwanese computer systems is initiated from wit...

  2. New Insights from Inside-Out Doppler Tomography

    Directory of Open Access Journals (Sweden)

    E. J. Kotze

    2015-02-01

    Full Text Available We present preliminary results from our investigation into using an “inside-out” velocity space for creating a Doppler tomogram. The aim is to transpose the inverted appearance of the Cartesian velocity space used in normal Doppler tomography. In a comparison between normal and inside-out Doppler tomograms of cataclysmic variables, we show that the inside-out velocity space has the potential to produce new insights into the accretion dynamics in these systems.

  3. Strategic Insights. Volume 10, Issue 1, Spring 2011

    Science.gov (United States)

    2011-01-01

    weapons in our arsenal and ban chemical and biological weapons. With persistence, there are solutions. A way around the attribution problem may be to...metal and plastic . America needs the ability to carpet bomb in cyberspace to create the deterrent we lack.13 In other words, Williamson was not only...Insights • Spring 2011 Volume 10, Issue 1 25 Cyber Conflict Between Taiwan and China Yao-chung Chang Introduction The Republic of China ( Taiwan

  4. The Turbulent Interstellar Medium: Insights and Questions from Numerical Models

    OpenAIRE

    Mac Low, Mordecai-Mark; de Avillez, Miguel A.; Korpi, Maarit J.

    2003-01-01

    "The purpose of numerical models is not numbers but insight." (Hamming) In the spirit of this adage, and of Don Cox's approach to scientific speaking, we discuss the questions that the latest generation of numerical models of the interstellar medium raise, at least for us. The energy source for the interstellar turbulence is still under discussion. We review the argument for supernovae dominating in star forming regions. Magnetorotational instability has been suggested as a way of coupling di...

  5. Strategic Insights. Volume 10, Issue 3, Winter 2011

    Science.gov (United States)

    2011-01-01

    fighting power of NATO has been much reduced. Superior fighting power over all-comers is the creed of US forces and should be the sine qua non of...undertaken by Joint Command Lisbon, Portugal – under the overall command of Allied Command Operations – where the local responsibility for the NATO SMLO... Portugal . http://www.nato.int/lisbon2010/strategic-concept- 2010-eng.pdf (accessed May 30, 2011). Strategic Insights • Winter 2011 Volume 10, Issue 3 39

  6. Canadian insights: The challenges of an integrated environmental assessment framework

    International Nuclear Information System (INIS)

    McCaig, Karen

    2005-01-01

    The paper draws results from a review of literature to examine the strengths and weaknesses of the integrated environmental assessment framework in Canada with respect to the inclusion of health impact assessment. Insights include the legislative nature, rigid structure and priority for the natural environment that may restrict progress and the pool of government agencies that need to be convinced of the benefits of health impact assessment that may provide a strong structure for compliance in the long term

  7. Young people and the labour market | Bhorat | Africa Insight

    African Journals Online (AJOL)

    No Abstract. Africa Insight Vol. 37 (3) 2007: pp. 388-403. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/ai.v37i3.22498 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

  8. Insight into carrier lifetime impact on band-modulation devices

    Science.gov (United States)

    Parihar, Mukta Singh; Lee, Kyung Hwa; Park, Hyung Jin; Lacord, Joris; Martinie, Sébastien; Barbé, Jean-Charles; Xu, Yue; El Dirani, Hassan; Taur, Yuan; Cristoloveanu, Sorin; Bawedin, Maryline

    2018-05-01

    A systematic study to model and characterize the band-modulation Z2-FET device is developed bringing light to the relevance of the carrier lifetime influence. This work provides guidelines to optimize the Z2-FETs for sharp switching, ESD protection, and 1T-DRAM applications. Lower carrier lifetime in the Z2-FET helps in attaining the sharp switch. We provide new insights into the correlation between generation/recombination, diffusion, electrostatic barriers and carrier lifetime.

  9. Determining female consumer’s insight into products and shopping

    OpenAIRE

    Firend, A.R

    2017-01-01

    This research explores consumer’s insight into the female sportswear segment for the purpose of improving product development in the clothing industry in South-East Asia, a consumer base consisting of 500 million people. The research aims to clarify the important parameters on which buying decisions are made. The parameters are based on price, function, fit, brand, and design. The methodology used in this research is qualitative and quantitative consisting of participative observations, in-de...

  10. novel insights into spatial and functional organization in the cell ...

    Indian Academy of Sciences (India)

    NOVEL INSIGHTS INTO SPATIAL AND FUNCTIONAL ORGANIZATION IN THE CELL NUCLEUS · PowerPoint Presentation · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Slide 8 · Slide 9 · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22.

  11. Insight na psicose: uma análise conceitual

    Directory of Open Access Journals (Sweden)

    Lucas F. B. Mella

    2011-01-01

    Full Text Available INTRODUÇÃO: No contexto da psiquiatria clínica, insight ou crítica da doença é definida como uma subcategoria do autoconhecimento dos pacientes relativa ao reconhecimento das manifestações patológicas que os afetam e também à apreciação das mudanças que tais manifestações causam na sua interação com o mundo. OBJETIVO: Examinar as formas de apresentação do insight na esquizofrenia e em outras psicoses. MÉTODOS: Análise conceitual, com vinhetas clínicas ilustrativas, da relação entre insight e as diversas dimensões sintomatológicas da esquizofrenia e condições relacionadas, considerando aspectos clínicos, neurocognitivos, psicodinâmicos e transculturais. RESULTADOS: Do ponto de vista conceitual, o construto é conformado pela perspectiva teórica adotada; do ponto de vista clínico, sua apresentação nas psicoses é a resultante da interação com os diferentes domínios sintomatológicos e aspectos subjetivos e culturais do paciente. CONCLUSÃO: A avaliação psicopatológica do insight deve levar em conta a complexidade do fenômeno, o recorte teórico em que está situada e a finalidade clínica com que é realizada.

  12. XPIWIT--an XML pipeline wrapper for the Insight Toolkit.

    Science.gov (United States)

    Bartschat, Andreas; Hübner, Eduard; Reischl, Markus; Mikut, Ralf; Stegmaier, Johannes

    2016-01-15

    The Insight Toolkit offers plenty of features for multidimensional image analysis. Current implementations, however, often suffer either from a lack of flexibility due to hard-coded C++ pipelines for a certain task or by slow execution times, e.g. caused by inefficient implementations or multiple read/write operations for separate filter execution. We present an XML-based wrapper application for the Insight Toolkit that combines the performance of a pure C++ implementation with an easy-to-use graphical setup of dynamic image analysis pipelines. Created XML pipelines can be interpreted and executed by XPIWIT in console mode either locally or on large clusters. We successfully applied the software tool for the automated analysis of terabyte-scale, time-resolved 3D image data of zebrafish embryos. XPIWIT is implemented in C++ using the Insight Toolkit and the Qt SDK. It has been successfully compiled and tested under Windows and Unix-based systems. Software and documentation are distributed under Apache 2.0 license and are publicly available for download at https://bitbucket.org/jstegmaier/xpiwit/downloads/. johannes.stegmaier@kit.edu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Incorporating evolutionary insights to improve ecotoxicology for freshwater species

    Science.gov (United States)

    Brady, Steven P.; Richardson, Jonathan L.; Kunz, Bethany K.

    2017-01-01

    Ecotoxicological studies have provided extensive insights into the lethal and sublethal effects of environmental contaminants. These insights are critical for environmental regulatory frameworks, which rely on knowledge of toxicity for developing policies to manage contaminants. While varied approaches have been applied to ecotoxicological questions, perspectives related to the evolutionary history of focal species or populations have received little consideration. Here, we evaluate chloride toxicity from the perspectives of both macroevolution and contemporary evolution. First, by mapping chloride toxicity values derived from the literature onto a phylogeny of macroinvertebrates, fish, and amphibians, we tested whether macroevolutionary relationships across species and taxa are predictive of chloride tolerance. Next, we conducted chloride exposure tests for two amphibian species to assess whether potential contemporary evolutionary change associated with environmental chloride contamination influences chloride tolerance across local populations. We show that explicitly evaluating both macroevolution and contemporary evolution can provide important and even qualitatively different insights from those obtained via traditional ecotoxicological studies. While macroevolutionary perspectives can help forecast toxicological end points for species with untested sensitivities, contemporary evolutionary perspectives demonstrate the need to consider the environmental context of exposed populations when measuring toxicity. Accounting for divergence among populations of interest can provide more accurate and relevant information related to the sensitivity of populations that may be evolving in response to selection from contaminant exposure. Our data show that approaches accounting for and specifically examining variation among natural populations should become standard practice in ecotoxicology.

  14. Ruminant Nutrition Symposium: Acidosis: new insights into the persistent problem.

    Science.gov (United States)

    Oba, M; Wertz-Lutz, A E

    2011-04-01

    The Ruminant Nutrition Symposium titled "Acidosis: New insights into the persistent problem" was held at the Joint Annual Meeting of the American Dairy Science Association, American Society of Animal Science, Poultry Science Association, Asociación Mexicana de Producción Animal, Western Section-ASAS, and the Canadian Society of Animal Science in Denver, Colorado, July 11 to 15, 2010. The objective of the symposium was to provide the ruminant nutrition community with new insights and perspectives from recent research findings on acidosis. Under modern production systems, ruminants are fed high-grain diets to maximize their energy intake and productivity. However, feeding highly fermentable diets often causes excess fermentation and results in accumulation of fermentation acids in the rumen, leading to a decrease in feed intake, poor feed efficiency, liver abscesses, and lameness in feedlot cattle or lactating dairy cows. Although our understanding of nutritional factors (i.e., effects of type and processing method of grains and importance of physically effective fiber) affecting rumen pH have increased substantially over the past few decades, rumen acidosis has continued to be a common problem in the ruminant livestock industry. The symposium program was organized to review recent research findings in acidosis with more emphasis on physiological aspects, and provide novel insights into the persistent problem.

  15. Insight in bipolar disorder : associations with cognitive and emotional processing and illness characteristics

    NARCIS (Netherlands)

    van der Werf - Eldering, Marieke; van der Meer, Lisette; Burger, Huibert; Holthausen, Esther; Nolen, W.A.; Aleman, Andre

    Objective: To investigate the multifactorial relationship between illness insight, cognitive and emotional processes, and illness characteristics in bipolar disorder patients. Methods: Data from 85 euthymic or mildly to moderately depressed bipolar disorder patients were evaluated. Insight was

  16. Right Hemispheric Dominance of Creative Insight: An Event-Related Potential Study

    Science.gov (United States)

    Shen, Wangbing; Liu, Chang; Zhang, Xiaojiang; Zhao, Xiaojun; Zhang, Jing; Yuan, Yuan; Chen, Yalin

    2013-01-01

    The purpose of this study was to investigate the hemispheric effect of creative insight. This study used high-density ERPs to record participants' brain activity while they performed an insight task. Results showed that both insight solutions and incomprehension solutions elicited a more negative ERP deflection (N320~550) than noninsight solutions…

  17. Self-Reflection, Insight, and Individual Differences in Various Language Tasks

    Science.gov (United States)

    Xu, Xu

    2011-01-01

    This study explored the relationships of self-reflection and insight with individuals' performances on various language tasks. The Self-Reflection and Insight Scale (SRIS; Grant, Franklin, & Langford, 2002) assessed individual differences in three factors: engagement in reflection, need for reflection, and insight. A high need for reflection was…

  18. Unraveling interrelationships among psychopathology symptoms, cognitive domains and insight dimensions in chronic schizophrenia.

    Science.gov (United States)

    Xavier, Rose Mary; Pan, Wei; Dungan, Jennifer R; Keefe, Richard S E; Vorderstrasse, Allison

    2018-03-01

    Insight in schizophrenia is long known to have a complex relationship with psychopathology symptoms and cognition. However, very few studies have examined models that explain these interrelationships. In a large sample derived from the NIMH Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial (N=1391), we interrogated these interrelationships for potential causal pathways using structural equation modeling. Using the NIMH consensus model, latent variables were constructed for psychopathology symptom dimensions, including positive, negative, disorganized, excited and depressed from the Positive and Negative Syndrome Scale (PANSS) items. Neurocognitive variables were created from five predefined domains of working memory, verbal memory, reasoning, vigilance and processing speed. Illness insight and treatment insight were tested using latent variables constructed from the Illness and Treatment Attitude Questionnaire (ITAQ). Disorganized symptoms had the strongest effect on insight. Illness insight mediated the relationship of positive, depressed, and disorganized symptoms with treatment insight. Neurocognition mediated the relationship between disorganized and treatment insight and depressed symptoms and treatment insight. There was no effect of negative symptoms on either illness insight or treatment insight. Taken together, our results indicate overlapping and unique relational paths for illness and treatment insight dimensions, which could suggest differences in causal mechanisms and potential interventions to improve insight. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Self-clarity and different clusters of insight and self-stigma in mental illness.

    Science.gov (United States)

    Hasson-Ohayon, Ilanit; Mashiach-Eizenberg, Michal; Lysaker, Paul H; Roe, David

    2016-06-30

    The current study explored the self-experience of persons with Serious Mental Illness (SMI) by investigating the associations between different insight and self-stigma clusters, self-clarity, hope, recovery, and functioning. One hundred seven persons diagnosed with a SMI were administered six scales: self-concept clarity, self-stigma, insight into the illness, hope, recovery, and functioning. Correlations and cluster analyses were performed. Insight, as measured by a self-report scale was not related to any other variable. Self-stigma was negatively associated with self-clarity, hope, recovery and functioning. Three clusters emerged: moderate stigma/high insight (n=31), high stigma/moderate insight (n=28), and low stigma/low insight (n=42). The group with low stigma and low insight had higher mean levels of self-clarity and hope than the other two groups. There were no significant differences between cluster 1 (moderate stigma/high insight) and cluster 2 (high stigma/moderate insight) in all the variables beside self-clarity. The group with moderate stigma and high insight had significantly higher mean levels of self-clarity than the group with high stigma and moderate insight. Results reveal that when people diagnosed with SMI do not have high levels of self-stigma they often report a positive and clear sense of self accompanied with hope, regardless of having low insight. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. Insight in bipolar mania: evaluation of its heterogeneity and correlation with clinical symptoms.

    Science.gov (United States)

    Silva, Rafael de Assis da; Mograbi, Daniel C; Bifano, Jaqueline; Santana, Cristina M T; Cheniaux, Elie

    2016-07-15

    Studies on insight in bipolar mania are not numerous and usually consider insight as a unitary construct. Evaluate how different facets of insight are affected in bipolar mania and investigate correlations between insight for each specific object in bipolar disorder and manic symptomatology. A group of 165 bipolar patients were followed during a year, with 51 patients having manic episodes according to DSM-IV-TR criteria. Patients underwent a clinical assessment and insight was evaluated through the Insight Scale for Affective Disorders. The study found that insight regarding symptoms is worse than insight of having bipolar disorder, social relationships and self esteem. Moreover, poor global insight (total ISAD) correlates with more severe changes in mood, speech and thought structure, with worse insight about symptoms correlating with the same alterations and also with more severe symptoms of agitation/energy. Although a large sample of bipolar patients was followed up, the final sample composed of patients with at least one manic episode was relatively smaller. Moreover, the fact that the study was performed in a university hospital may have led to selection biases. Results suggest that patients with BD are reasonably capable of identifying that their condition implies consequences but have more impaired awareness of their energy and activity levels. A lower level of insight specifically about symptoms correlates with more severe symptoms of agitation/energy, which suggests a psychomotor nucleus able to impair insight in mania. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Insight change in psychosis : relationship with neurocognition, social cognition, clinical symptoms and phase of illness

    NARCIS (Netherlands)

    Quee, P. J.; van der Meer, L.; Krabbendam, L.; de Haan, L.; Cahn, W.; Wiersma, D.; van Beveren, N.; Pijnenborg, G. H. M.; Mulder, C. L.; Bruggeman, R.; Aleman, A.

    Objective: Impaired insight is an important and prevalent symptom of psychosis. It remains unclear whether cognitive disturbances hamper improvements in insight. We investigated the neurocognitive, social cognitive, and clinical correlates of changes in insight. Method: One hundred and fifty-four

  2. Relationship between cognition, clinical and cognitive insight in psychotic disorders : A review and meta-analysis

    NARCIS (Netherlands)

    Nair, Akshay; Palmer, Emma Claire; Aleman, Andre; David, Anthony S.

    The neurocognitive theory of insight posits that poor insight in psychotic illnesses is related to cognitive deficits in cognitive self-appraisal mechanisms. In this paper we perform a comprehensive meta-analysis examining relationships between clinical insight and neurocognition in psychotic

  3. DMPD: New insights into the regulation of TLR signaling. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16698941 New insights into the regulation of TLR signaling. Miggin SM, O'Neill LA. ...J Leukoc Biol. 2006 Aug;80(2):220-6. Epub 2006 May 12. (.png) (.svg) (.html) (.csml) Show New insights into ...the regulation of TLR signaling. PubmedID 16698941 Title New insights into the regulation of TLR signaling.

  4. Implicit and explicit self-related processing in relation to insight in patients with schizophrenia

    NARCIS (Netherlands)

    de Vos, Annerieke E.; Pijnenborg, Gerdina H. M.; Aleman, Andre; van der Meer, Lisette

    2015-01-01

    Introduction. Self-related processing (SRP) has been associated with clinical and cognitive insight. We investigated the relationship between implicit SRP (ISRP) and explicit SRP (ESRP) and insight. We first hypothesised that impaired insight is associated with the extent to which implicit feedback

  5. The effects of aging on insight into illness in schizophrenia: a review†

    Science.gov (United States)

    Gerretsen, Philip; Plitman, Eric; Rajji, Tarek K.; Graff-Guerrero, Ariel

    2015-01-01

    Objectives Impaired insight into illness is a prevalent feature of schizophrenia, which negatively influences treatment adherence and clinical outcomes. Little is known about the effects of aging on insight impairment. We aimed to review the available research literature on the effects of aging on insight into illness in schizophrenia, in relation to positive, negative, and cognitive symptoms. Ultimately, we propose a trajectory of insight in schizophrenia across the lifespan. Method A systematic Medline® literature search was conducted, searching for English language studies describing the relationship of insight into illness in schizophrenia with aging. Results We identified 62 studies. Insight impairment is associated with illness severity, premorbid intellectual function (i.e. IQ), executive function, and memory. Insight impairment improves modestly during midlife, worsening again in late life. It tends to fluctuate with each episode of psychosis, likely in relation to worsening positive symptoms that improve with antipsychotic treatment. The relationship between insight impairment and cognitive dysfunction appears to attenuate with age, while the relationship with lower premorbid intellectual function is preserved. The association between impaired insight and negative symptoms is unclear. Conclusions The available literature suggests that the course of insight impairment follows a U-shaped curve, where insight impairment is severe during the first episode of psychosis, modestly improves over midlife, and declines again in late life. Future studies are required to investigate the trajectory of insight into illness and its core domains across the lifespan from prodromal phase to late life. PMID:25055980

  6. The Client's Potential for Therapeutic Insight Assessed through the Ability to Reflect Verbally and Musically

    DEFF Research Database (Denmark)

    Hannibal, Niels

    1999-01-01

    This article will focus on the question of how verbal reflection about music, and musical reflection while playing, can be described with the purpose of assessing a person's possibility to achieve insight in music therapy: The insight potential. The concept of the insight potential is related to ...

  7. Unraveling the insight paradox: One-year longitudinal study on the relationships between insight, self-stigma, and life satisfaction among people with schizophrenia spectrum disorders.

    Science.gov (United States)

    Chio, Floria H N; Mak, Winnie W S; Chan, Randolph C H; Tong, Alan C Y

    2018-01-30

    The promotion of insight among people with schizophrenia spectrum disorders has posed a dilemma to service providers as higher insight has been linked to positive clinical outcomes but negative psychological outcomes. The negative meaning that people attached to the illness (self-stigma content) and the recurrence of such stigmatizing thoughts (self-stigma process) may explain why increased insight is associated with negative outcomes. The present study examined how the presence of high self-stigma content and self-stigma process may contribute to the negative association between insight and life satisfaction. A total of 181 people with schizophrenia spectrum disorders were assessed at baseline. 130 and 110 participants were retained and completed questionnaire at 6-month and 1-year follow-up, respectively. Results showed that baseline insight was associated with lower life satisfaction at 6-month when self-stigma process or self-stigma content was high. Furthermore, baseline insight was predictive of better life satisfaction at 1-year follow-up when self-stigma process was low. Findings suggested that the detrimental effects of insight can be a result from both the presence of cognitive content and habitual process of self-stigma. Future insight promotion interventions should also address self-stigma content and process among people with schizophrenia spectrum disorders so as to maximize the beneficial effects of insight. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. 77 FR 14832 - Plumchoice, Inc., Including On-Site Leased Workers From Balance Staffing, Insight Global Staffing...

    Science.gov (United States)

    2012-03-13

    ...., Including On-Site Leased Workers From Balance Staffing, Insight Global Staffing, and Technisource..., Insight Global Staffing, and Technisource, Scarborough, Maine. The workers are engaged in activities... leased workers from Balance Staffing, Insight Global Staffing, and Technisource, Scarborough, Maine, who...

  9. [Insight and psychiatric dangerousness: A review of the literature].

    Science.gov (United States)

    Bonnet, S; Lacambre, M; Schandrin, A; Capdevielle, D; Courtet, P

    2017-04-01

    Violence committed by individuals with severe mental illness has become an increasing focus of concern among clinicians, policy makers, and the general public, often as the result of tragic events. Research has shown in the past two decades an increased risk of violence among patients with mental disorder. Nevertheless, of those suffering from mental illness, perpetrators of other directed violence form a minority subgroup. The means by which there is this association between mental illness and violence has remained controversial. Factors such as positive psychotic symptoms, medication non-adherence, alcohol or psychoactive substance abuse and antisocial personality were found to be predictive of violence. Overall, literature provides support to the assertion that violent behavior of mentally ill patients is a heterogeneous phenomenon that is driven by multiple inter-related and independent factors. Furthermore, psychiatrists are often asked to predict an individual's future dangerousness, in a medical or a legal context. In the process of risk assessment of dangerousness, more focus has been placed on dynamic risk factor. In this context, lack of insight has established itself both as a part of violence risk models and as a clinical item in structured approaches to measure dangerousness. However, few studies have tested these associations. The main purpose of this paper is to review the literature concerning the relationship between insight and dangerousness and discuss the contributions of the insight in the assessment of dangerousness in patients with mental illness. We included twenty studies that evaluated the association between insight and variable such as physical or verbal violence, aggressiveness, hostility or sexual aggression. According to the findings of this review, the strength and specific nature of this relationship remain unclear due to considerable methodological and conceptual shortcomings, including heterogeneity in the definition and

  10. The Use and Incorporation of Extralegal Insights in Legal Reasoning

    Directory of Open Access Journals (Sweden)

    Ivo Giesen

    2015-01-01

    Full Text Available Following the US example, European scholarship has seen more and more interdisciplinary or multidisciplinary academic work being carried out over the last few decades, not only in criminal law but also relating to private law and civil procedure. In such studies ‘extralegal’ knowledge from, for example, psychology, sociology and economics, is combined with existing legal insights and transformed into ‘novel’ legal knowledge. This has often led to new thoughts on how to organize our legal landscape and to new public policy issues and solutions.An intriguing question underlying these studies is whether it is in fact possible – and if so, how, why and when – to leap from such ‘extralegal’ insights to normative legal conclusions. How and when can any researcher step over from, for example, empirical psychological facts to legal normative value judgments (as one is required to do from a legal end, for instance as a judge ruling on a case? What, if anything, allows anyone to do so? What are the conditions under which it would be safe to say that one could cross over from one side to the other?By reviewing the existing methodological literature on this topic and by linking up with ideas about the (analogous use of comparative law materials, this paper – methodological in nature – tries to come up with a workable ‘method’ for crossing the border between social science disciplines and the law. As it turns out, a due process approach is the best available option. This approach asks of judges, practitioners and scholars to become familiar with the methodology of the social sciences. That hurdle might be overcome by using court-appointed experts to evaluate the usefulness of the extralegal materials. The judge would thus resort to an expert to advise him on how to be a decent gatekeeper when it comes to the possible use of insights from social sciences.

  11. New insights into the evolutionary history of biological nitrogen fixation

    Directory of Open Access Journals (Sweden)

    Eric eBoyd

    2013-08-01

    Full Text Available Nitrogenase, which catalyzes the ATP-dependent reduction of dinitrogen (N2 to ammonia (NH3, accounts for roughly half of the bioavailable nitrogen supporting extant life. The fundamental requirement for fixed forms of nitrogen for life on Earth, both at present and in the past, has led to broad and significant interest in the origin and evolution of this fundamental biological process. One key question is whether the limited availability of fixed nitrogen was a factor in life’s origin or whether there were ample sources of fixed nitrogen produced by abiotic processes or delivered through the weathering of bolide impact materials to support this early life. If the latter, the key questions become what were the characteristics of the environment that precipitated the evolution of this oxygen sensitive process, when did this occur, and how was its subsequent evolutionary history impacted by the advent of oxygenic photosynthesis and the rise of oxygen in the Earth’s biosphere. Since the availability of fixed sources of nitrogen capable of supporting early life is difficult to glean from the geologic record, there are limited means to get direct insights into these questions. Indirect insights, however, can be gained by deep phylogenetic studies of nitrogenase structural gene products and additional gene products involved in the biosynthesis of the complex metal-containing prosthetic groups associated with this enzyme complex. Insights gained from such studies, as reviewed herein, challenge traditional models for the evolution of biological nitrogen fixation and provide the basis for the development of new conceptual models that explain the stepwise evolution of this highly complex and life sustaining process.

  12. Physically-insightful equivalent circuit models for electromagnetic periodic structures

    Science.gov (United States)

    Mesa, F.; Rodríguez-Berral, R.; Medina, F.

    2018-02-01

    In this presentation it will be discussed how to obtain analytical or quasi-analytical equivalent circuits to deal with periodic structures such as frequency selective surfaces and/or metasurfaces. Both the topology and the values of the involved elements of these circuits are obtained from a basic rationale to solve the corresponding integral equation. This procedure, besides providing a very efficient analysis/design tool, allows for a good physical insight into the operating mechanisms of the structure in contrast with the almost blind numerical scheme of commercial simulators.

  13. AN INSIGHT INTO STAKEHOLDER-LED CSR COMMUNICATION

    Directory of Open Access Journals (Sweden)

    Olesia Mihai

    2012-11-01

    Full Text Available Although companies have always been engaged in communicating strategically with the main stakeholders, recent developments have shown that the corporate communication function has been redefined as a complex activity of communicating with both internal and external stakeholders. The authors use stakeholder theory to provide insight into CSR on-line communication by analyzing the content available to the general public of three major Romanian companies. The analysis shows that Romanian companies have adopted mainly the engagement rhetoric, one of the explanations being the fact that many domestic stakeholders still fail to understand the key role of CSR in developing corporate identity and reputation via on-line communication.

  14. New Insights into the Microbiota of Moth Pests.

    Science.gov (United States)

    Mereghetti, Valeria; Chouaia, Bessem; Montagna, Matteo

    2017-11-18

    In recent years, next generation sequencing (NGS) technologies have helped to improve our understanding of the bacterial communities associated with insects, shedding light on their wide taxonomic and functional diversity. To date, little is known about the microbiota of lepidopterans, which includes some of the most damaging agricultural and forest pests worldwide. Studying their microbiota could help us better understand their ecology and offer insights into developing new pest control strategies. In this paper, we review the literature pertaining to the microbiota of lepidopterans with a focus on pests, and highlight potential recurrent patterns regarding microbiota structure and composition.

  15. An insight into the future beckons of maxillofacial prosthodontics: Anaplastology

    Directory of Open Access Journals (Sweden)

    S Padmaja

    2015-01-01

    Full Text Available It is the god given right of every human being to appear human. Few areas of dentistry offer more challenges to the technical skills or greater satisfaction for the successful rehabilitation of function and esthetics in the patient with gross anatomic defects and deformities of the maxillofacial region. Although remarkable advances in the surgical management of oral and facial defects, but cannot be satisfactorily repaired by plastic surgery alone. Hence, the demand for maxillofacial prosthetic devices for the rehabilitation of patients with congenital or acquired defects has intensified in recent years. This paper gives an insight into the latest innovations and improvisations in the field of maxillofacial prosthodontics.

  16. Genomic insights into the Saccharomyces sensu stricto complex.

    Science.gov (United States)

    Borneman, Anthony R; Pretorius, Isak S

    2015-02-01

    The Saccharomyces sensu stricto group encompasses species ranging from the industrially ubiquitous yeast Saccharomyces cerevisiae to those that are confined to geographically limited environmental niches. The wealth of genomic data that are now available for the Saccharomyces genus is providing unprecedented insights into the genomic processes that can drive speciation and evolution, both in the natural environment and in response to human-driven selective forces during the historical "domestication" of these yeasts for baking, brewing, and winemaking. Copyright © 2015 by the Genetics Society of America.

  17. Cellulases from Thermophilic Fungi: Recent Insights and Biotechnological Potential

    Directory of Open Access Journals (Sweden)

    Duo-Chuan Li

    2011-01-01

    Full Text Available Thermophilic fungal cellulases are promising enzymes in protein engineering efforts aimed at optimizing industrial processes, such as biomass degradation and biofuel production. The cloning and expression in recent years of new cellulase genes from thermophilic fungi have led to a better understanding of cellulose degradation in these species. Moreover, crystal structures of thermophilic fungal cellulases are now available, providing insights into their function and stability. The present paper is focused on recent progress in cloning, expression, regulation, and structure of thermophilic fungal cellulases and the current research efforts to improve their properties for better use in biotechnological applications.

  18. Novel insights into the microbiology of fermented dairy foods.

    Science.gov (United States)

    Macori, Guerrino; Cotter, Paul D

    2018-02-01

    Fermentation is a traditional approach to food preservation that, in addition to improving food safety, also confers enhanced organoleptic, nutritional, and health-promoting attributes upon those foods. Dairy products can be fermented by a diverse microbiota. The accompanying microbes can be studied using a variety of different, including 'omics'-based, approaches that can reveal their composition and functionality. These methods have increasingly been recently applied to study fermented dairy foods from the perspective of genetic diversity, functionality and succession. The insights provided by these studies are summarised in this review. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Reduced connectivity in the self-processing network of schizophrenia patients with poor insight.

    Directory of Open Access Journals (Sweden)

    Edith J Liemburg

    Full Text Available Lack of insight (unawareness of illness is a common and clinically relevant feature of schizophrenia. Reduced levels of self-referential processing have been proposed as a mechanism underlying poor insight. The default mode network (DMN has been implicated as a key node in the circuit for self-referential processing. We hypothesized that during resting state the DMN network would show decreased connectivity in schizophrenia patients with poor insight compared to patients with good insight. Patients with schizophrenia were recruited from mental health care centers in the north of the Netherlands and categorized in groups having good insight (n= 25 or poor insight (n = 19. All subjects underwent a resting state fMRI scan. A healthy control group (n = 30 was used as a reference. Functional connectivity of the anterior and posterior part of the DMN, identified using Independent Component Analysis, was compared between groups. Patients with poor insight showed lower connectivity of the ACC within the anterior DMN component and precuneus within the posterior DMN component compared to patients with good insight. Connectivity between the anterior and posterior part of the DMN was lower in patients than controls, and qualitatively different between the good and poor insight patient groups. As predicted, subjects with poor insight in psychosis showed decreased connectivity in DMN regions implicated in self-referential processing, although this concerned only part of the network. This finding is compatible with theories implying a role of reduced self-referential processing as a mechanism contributing to poor insight.

  20. The relative contributions of social cognition and self-reflectiveness to clinical insight in enduring schizophrenia.

    Science.gov (United States)

    Béland, Sophie; Lepage, Martin

    2017-12-01

    Poor clinical insight represents a major barrier to recovery in schizophrenia. Research suggests that higher-order social cognitive abilities such as theory of mind (TOM) and metacognition contribute to levels of clinical insight. However, few studies have examined whether social cognitive abilities other than TOM are related to clinical insight. Moreover, to date, no investigation has attempted to determine whether the contribution of metacognitive ability to clinical insight can be differentiated from the contribution of higher-order social cognition, despite their conceptual similarity. Therefore, the purpose of this study was to examine the relative contribution of different social cognitive abilities, as well as metacognition, to clinical insight in a large sample of 139 enduring schizophrenia patients, and controlling for established predictors of clinical insight. Hierarchical regression analyses were used to evaluate the portion of variance explained by 3 social cognitive abilities: emotion recognition, TOM, and affective empathy, and the metacognitive ability of self-reflectiveness. Clinical insight levels were assessed using the Schedule for the Assessment of Insight-Expanded version. Results indicated that affective empathy and self-reflectiveness are the strongest predictors of clinical insight. These results provide insights on the development of targeted interventions for improving clinical insight in this population. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Insight, Neurocognition, and Schizophrenia: Predictive Value of the Wisconsin Card Sorting Test

    Science.gov (United States)

    Yanos, Philip T.

    2013-01-01

    Lack of insight in schizophrenia is a key feature of the illness and is associated with both positive and negative clinical outcomes. Previous research supports that neurocognitive dysfunction is related to lack of insight, but studies have not examined how neurocognition relates to change in insight over time. Therefore, the current study sought to understand how performance on the Wisconsin Card Sorting Test (WCST) differed between participants with varying degrees of change in insight over a 6-month period. Fifty-two patients with schizophrenia or schizoaffective disorder were administered the WCST and Positive and Negative Syndrome Scale (PANSS) at baseline, and the PANSS was again administered at a 6-month follow-up assessment. Results indicated that while neurocognition was related to insight at baseline, it was not related to subsequent change in insight. The implications of findings for conceptualization and assessment of insight are discussed. PMID:24303216

  2. Categories of Insight and Their Correlates: An Exploration of Relationships among Classic-Type Insight Problems, Rebus Puzzles, Remote Associates and Esoteric Analogies

    Science.gov (United States)

    Cunningham, J. Barton; MacGregor, James N.; Gibb, Jenny; Haar, Jarrod

    2009-01-01

    A central question in creativity concerns how insightful ideas emerge. Anecdotal examples of insightful scientific and technical discoveries include Goodyear's discovery of the vulcanization of rubber, and Mendeleev's realization that there may be gaps as he tried to arrange the elements into the Periodic Table. Although most people would regard…

  3. Unanticipated Insights into Biomedicine from the Study of Acupuncture.

    Science.gov (United States)

    MacPherson, Hugh; Hammerschlag, Richard; Coeytaux, Remy R; Davis, Robert T; Harris, Richard E; Kong, Jiang-Ti; Langevin, Helene M; Lao, Lixing; Milley, Ryan J; Napadow, Vitaly; Schnyer, Rosa N; Stener-Victorin, Elisabet; Witt, Claudia M; Wayne, Peter M

    2016-02-01

    Research into acupuncture has had ripple effects beyond the field of acupuncture. This paper identifies five exemplars to illustrate that there is tangible evidence of the way insights gleaned from acupuncture research have informed biomedical research, practice, or policy. The first exemplar documents how early research into acupuncture analgesia has expanded into neuroimaging research, broadening physiologic understanding and treatment of chronic pain. The second describes how the acupuncture needle has become a tool to enhance biomedical knowledge of connective tissue. The third exemplar, which illustrates use of a modified acupuncture needle as a sham device, focuses on emergent understanding of placebo effects and, in turn, on insights into therapeutic encounters in treatments unrelated to acupuncture. The fourth exemplar documents that two medical devices now in widespread use were inspired by acupuncture: transcutaneous electrical nerve stimulators for pain control and antinausea wrist bands. The final exemplar describes how pragmatic clinical trial designs applied in acupuncture research have informed current general interest in comparative effectiveness research. In conclusion, these exemplars of unanticipated outcomes of acupuncture research comprise an additional rationale for continued support of basic and clinical research evaluating acupuncture and other under-researched therapies.

  4. Insights into the structural biology of Gaucher disease.

    Science.gov (United States)

    Smith, Laura; Mullin, Stephen; Schapira, Anthony H V

    2017-12-01

    Gaucher disease, the most common lysosomal storage disorder, is caused by mutations in the gene encoding the acid-β-glucosidase lysosomal hydrolase enzyme that cleaves glucocerebroside into glucose and ceramide. Reduced enzyme activity and impaired structural stability arise due to >300 known disease-causing mutations. Several of these mutations have also been associated with an increased risk of Parkinson disease (PD). Since the discovery of the acid-β-glucosidase X-ray structure, there have been major advances in our understanding of the structural properties of the protein. Analysis of specific residues has provided insight into their functional and structural importance and provided insight into the pathogenesis of Gaucher disease and the contribution to PD. Disease-causing mutations are positioned throughout the acid-β-glucosidase structure, with many located far from the active site and thus retaining some enzymatic activity however, thus far no clear relationship between mutation location and disease severity has been established. Here, we review the crystal structure of acid-β-glucosidase, while highlighting important structural aspects of the protein in detail. This review discusses the structural stability of acid-β-glucosidase, which can be altered by pH and glycosylation, and explores the relationship between known Gaucher disease and PD mutations, structural stability and disease severity. Copyright © 2017. Published by Elsevier Inc.

  5. Neural signatures of attention: insights from decoding population activity patterns.

    Science.gov (United States)

    Sapountzis, Panagiotis; Gregoriou, Georgia G

    2018-01-01

    Understanding brain function and the computations that individual neurons and neuronal ensembles carry out during cognitive functions is one of the biggest challenges in neuroscientific research. To this end, invasive electrophysiological studies have provided important insights by recording the activity of single neurons in behaving animals. To average out noise, responses are typically averaged across repetitions and across neurons that are usually recorded on different days. However, the brain makes decisions on short time scales based on limited exposure to sensory stimulation by interpreting responses of populations of neurons on a moment to moment basis. Recent studies have employed machine-learning algorithms in attention and other cognitive tasks to decode the information content of distributed activity patterns across neuronal ensembles on a single trial basis. Here, we review results from studies that have used pattern-classification decoding approaches to explore the population representation of cognitive functions. These studies have offered significant insights into population coding mechanisms. Moreover, we discuss how such advances can aid the development of cognitive brain-computer interfaces.

  6. Insights from advanced analytics at the Veterans Health Administration.

    Science.gov (United States)

    Fihn, Stephan D; Francis, Joseph; Clancy, Carolyn; Nielson, Christopher; Nelson, Karin; Rumsfeld, John; Cullen, Theresa; Bates, Jack; Graham, Gail L

    2014-07-01

    Health care has lagged behind other industries in its use of advanced analytics. The Veterans Health Administration (VHA) has three decades of experience collecting data about the veterans it serves nationwide through locally developed information systems that use a common electronic health record. In 2006 the VHA began to build its Corporate Data Warehouse, a repository for patient-level data aggregated from across the VHA's national health system. This article provides a high-level overview of the VHA's evolution toward "big data," defined as the rapid evolution of applying advanced tools and approaches to large, complex, and rapidly changing data sets. It illustrates how advanced analysis is already supporting the VHA's activities, which range from routine clinical care of individual patients--for example, monitoring medication administration and predicting risk of adverse outcomes--to evaluating a systemwide initiative to bring the principles of the patient-centered medical home to all veterans. The article also shares some of the challenges, concerns, insights, and responses that have emerged along the way, such as the need to smoothly integrate new functions into clinical workflow. While the VHA is unique in many ways, its experience may offer important insights for other health care systems nationwide as they venture into the realm of big data. Project HOPE—The People-to-People Health Foundation, Inc.

  7. Formal thought disorder, neuropsychology and insight in schizophrenia.

    Science.gov (United States)

    Barrera, Alvaro; McKenna, Peter J; Berrios, German E

    2009-01-01

    Information provided by patients with schizophrenia and their respective carers is used to study the descriptive psychopathology and neuropsychology of formal thought disorder (FTD). Relatively intellectually preserved schizophrenia patients (n = 31) exhibiting from no to severe positive FTD completed a self-report scale of FTD, a scale of insight as well as several tests of executive and semantic function. The patients' carers completed another scale of FTD to assess the patients' speech. FTD as self-reported by patients was significantly associated with the synonyms test performance and severity of the reality distortion dimension. FTD as assessed by a clinician and by the patients' carers was significantly associated with executive test performance and performance in a test of associative semantics. Overall insight was significantly associated with severity of the reality distortion dimension and graded naming test performance, but was not associated with self-reported FTD or severity of FTD as assessed by the clinician or carers. The self-reported experience of FTD has different clinical and neuropsychological correlates from those of FTD as assessed by clinicians and carers. The assessment of FTD by patients and carers used along with the clinician's assessment may further the study of this group of symptoms. 2009 S. Karger AG, Basel.

  8. Hybrid discrete choice models: Gained insights versus increasing effort

    International Nuclear Information System (INIS)

    Mariel, Petr; Meyerhoff, Jürgen

    2016-01-01

    Hybrid choice models expand the standard models in discrete choice modelling by incorporating psychological factors as latent variables. They could therefore provide further insights into choice processes and underlying taste heterogeneity but the costs of estimating these models often significantly increase. This paper aims at comparing the results from a hybrid choice model and a classical random parameter logit. Point of departure for this analysis is whether researchers and practitioners should add hybrid choice models to their suite of models routinely estimated. Our comparison reveals, in line with the few prior studies, that hybrid models gain in efficiency by the inclusion of additional information. The use of one of the two proposed approaches, however, depends on the objective of the analysis. If disentangling preference heterogeneity is most important, hybrid model seems to be preferable. If the focus is on predictive power, a standard random parameter logit model might be the better choice. Finally, we give recommendations for an adequate use of hybrid choice models based on known principles of elementary scientific inference. - Highlights: • The paper compares performance of a Hybrid Choice Model (HCM) and a classical Random Parameter Logit (RPL) model. • The HCM indeed provides insights regarding preference heterogeneity not gained from the RPL. • The RPL has similar predictive power as the HCM in our data. • The costs of estimating HCM seem to be justified when learning more on taste heterogeneity is a major study objective.

  9. When to stop drying fruit: Insights from hygrothermal modelling

    International Nuclear Information System (INIS)

    Defraeye, Thijs

    2017-01-01

    Highlights: • Partial dehydration reduces energy consumption and processing time and improves product quality. • This study gives a quantitative insight in when fruit drying should be stopped. • Decrease in dryer residence time of 2%, 24% and 70% are found for different stopping criteria. - Abstract: Stopping the drying process prior to complete dehydration reduces energy consumption and processing time but can also improve product quality. Using hygrothermal simulations, different stopping criteria are evaluated, which are based on the final water activity and residual moisture content in the fruit. Their impact on drying time and moisture redistribution kinetics inside fruit is quantified. One of the variants leads to a significant reduction in residence time in the dryer (24%), compared to full dehydration. For this variant, drying is stopped when the average moisture content in the sample reaches the value corresponding to an equilibrium water activity of 60% in the sample, as determined from the sorption isotherm. At the same time, this variant does not induce problems with fruit spoilage, as a sufficiently low water activity is reached after moisture redistribution during relaxation in the ambient environment. In addition, the relation of the drying time to the drying air temperature was quantified for all stopping criteria, as well as the impact of the humidity of the ambient environment in which the dried fruits are placed afterwards. This study gives a better quantitative insight in when fruit drying should be stopped, given specific drying conditions, without having to compromise food safety.

  10. Hybrid discrete choice models: Gained insights versus increasing effort

    Energy Technology Data Exchange (ETDEWEB)

    Mariel, Petr, E-mail: petr.mariel@ehu.es [UPV/EHU, Economía Aplicada III, Avda. Lehendakari Aguire, 83, 48015 Bilbao (Spain); Meyerhoff, Jürgen [Institute for Landscape Architecture and Environmental Planning, Technical University of Berlin, D-10623 Berlin, Germany and The Kiel Institute for the World Economy, Duesternbrooker Weg 120, 24105 Kiel (Germany)

    2016-10-15

    Hybrid choice models expand the standard models in discrete choice modelling by incorporating psychological factors as latent variables. They could therefore provide further insights into choice processes and underlying taste heterogeneity but the costs of estimating these models often significantly increase. This paper aims at comparing the results from a hybrid choice model and a classical random parameter logit. Point of departure for this analysis is whether researchers and practitioners should add hybrid choice models to their suite of models routinely estimated. Our comparison reveals, in line with the few prior studies, that hybrid models gain in efficiency by the inclusion of additional information. The use of one of the two proposed approaches, however, depends on the objective of the analysis. If disentangling preference heterogeneity is most important, hybrid model seems to be preferable. If the focus is on predictive power, a standard random parameter logit model might be the better choice. Finally, we give recommendations for an adequate use of hybrid choice models based on known principles of elementary scientific inference. - Highlights: • The paper compares performance of a Hybrid Choice Model (HCM) and a classical Random Parameter Logit (RPL) model. • The HCM indeed provides insights regarding preference heterogeneity not gained from the RPL. • The RPL has similar predictive power as the HCM in our data. • The costs of estimating HCM seem to be justified when learning more on taste heterogeneity is a major study objective.

  11. Fetal programming by maternal stress: Insights from a conflict perspective.

    Science.gov (United States)

    Del Giudice, Marco

    2012-10-01

    Maternal stress during pregnancy has pervasive effects on the offspring's physiology and behavior, including the development of anxious, reactive temperament and increased stress responsivity. These outcomes can be seen as the result of adaptive developmental plasticity: maternal stress hormones carry useful information about the state of the external world, which can be used by the developing fetus to match its phenotype to the predicted environment. This account, however, neglects the inherent conflict of interest between mother and fetus about the outcomes of fetal programming. The aim of this paper is to extend the adaptive model of prenatal stress by framing mother-fetus interactions in an evolutionary conflict perspective. In the paper, I show how a conflict perspective provides many new insights in the functions and mechanisms of fetal programming, with particular emphasis on human pregnancy. I then take advantage of those insights to make sense of some puzzling features of maternal and fetal physiology and generate novel empirical predictions. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Using behavioural insights for citizen compliance and cooperation

    Directory of Open Access Journals (Sweden)

    Jane Robb

    2017-03-01

    Full Text Available In recent years, public agencies have frequently deployed behavioural insights to generate benefits for society, through encouraging citizens to comply with official requests, and more generally encouraging them to cooperate with public agencies to help deliver outcomes of collective benefit. In parallel, there has been a large increase in the amount and quality of the research evidence available on behavioural public policy. This review takes two contrasting areas where behavioural insights have been used: tax collection where government policy is compulsory (i.e. requiring compliance, and energy use where social objectives are non-compulsory, and achieved more by persuasion and encouragement. Processes of modifying and changing behaviour require different approaches whether the change is deemed necessary by the state or not. In taxes, the sole use of enforcement is rarely efficacious, whereas increasing the uncertainty of follow-up and audit increases compliance. Offering discounts for energy bills appears to be an effective method for achieving cooperation. However, the use of social norms and increased information and professional advice is effective for both compulsory and non-compulsory areas of compliance and cooperation. This has important implications for policymakers, who may be seeking effective methods of encouraging behaviour change. While there are differences in approaches for compulsory and non-compulsory areas of policy, there may be areas that move from non-statutory to statutory in the future. In this case, the development of desired social norms appears to be the most effective method of ensuring overall compliance.

  13. Cyclone Center: Insights on Historical Tropical Cyclones from Citizen Volunteers

    Science.gov (United States)

    Thorne, P.; Hennon, C. C.; Knapp, K. R.; Schreck, C. J., III; Stevens, S. E.; Kossin, J. P.; Rennie, J.; Hennon, P. A.; Kruk, M. C.

    2015-12-01

    The cyclonecenter.org project started in fall 2012 and has been collecting citizen scientist volunteer tropical cyclone intensity estimates ever since. The project is hosted by the Citizen Science Alliance (zooniverse) and the platform is supported by a range of scientists. We have over 30 years of satellite imagery of tropical cyclones but the analysis to date has been done on an ocean-basin by ocean-basin basis and worse still practices have changed over time. We therefore do not, presently, have a homogeneous record relevant for discerning climatic changes. Automated techniques can classify many of the images but have a propensity to be challenged during storm transitions. The problem is fundamentally one where many pairs of eyes are invaluable as there is no substitute for human eyes in discerning patterns. Each image is classified by ten unique users before it is retired. This provides a unique insight into the uncertainty inherent in classification. In the three years of the project much useful data has accrued. This presentation shall highlight some of the results and analyses to date and touch on insights as to what has worked and what perhaps has not worked so well. There are still many images left to complete so its far from too late to jump over to www.cyclonecenter.org and help out.

  14. Do people have insight into their face recognition abilities?

    Science.gov (United States)

    Palermo, Romina; Rossion, Bruno; Rhodes, Gillian; Laguesse, Renaud; Tez, Tolga; Hall, Bronwyn; Albonico, Andrea; Malaspina, Manuela; Daini, Roberta; Irons, Jessica; Al-Janabi, Shahd; Taylor, Libby C; Rivolta, Davide; McKone, Elinor

    2017-02-01

    Diagnosis of developmental or congenital prosopagnosia (CP) involves self-report of everyday face recognition difficulties, which are corroborated with poor performance on behavioural tests. This approach requires accurate self-evaluation. We examine the extent to which typical adults have insight into their face recognition abilities across four experiments involving nearly 300 participants. The experiments used five tests of face recognition ability: two that tap into the ability to learn and recognize previously unfamiliar faces [the Cambridge Face Memory Test, CFMT; Duchaine, B., & Nakayama, K. (2006). The Cambridge Face Memory Test: Results for neurologically intact individuals and an investigation of its validity using inverted face stimuli and prosopagnosic participants. Neuropsychologia, 44(4), 576-585. doi:10.1016/j.neuropsychologia.2005.07.001; and a newly devised test based on the CFMT but where the study phases involve watching short movies rather than viewing static faces-the CFMT-Films] and three that tap face matching [Benton Facial Recognition Test, BFRT; Benton, A., Sivan, A., Hamsher, K., Varney, N., & Spreen, O. (1983). Contribution to neuropsychological assessment. New York: Oxford University Press; and two recently devised sequential face matching tests]. Self-reported ability was measured with the 15-item Kennerknecht et al. questionnaire [Kennerknecht, I., Ho, N. Y., & Wong, V. C. (2008). Prevalence of hereditary prosopagnosia (HPA) in Hong Kong Chinese population. American Journal of Medical Genetics Part A, 146A(22), 2863-2870. doi:10.1002/ajmg.a.32552]; two single-item questions assessing face recognition ability; and a new 77-item meta-cognition questionnaire. Overall, we find that adults with typical face recognition abilities have only modest insight into their ability to recognize faces on behavioural tests. In a fifth experiment, we assess self-reported face recognition ability in people with CP and find that some people who expect to

  15. Sleeping beauties in theoretical physics 26 surprising insights

    CERN Document Server

    Padmanabhan, Thanu

    2015-01-01

    This book addresses a fascinating set of questions in theoretical physics which will both entertain and enlighten all students, teachers and researchers and other physics aficionados. These range from Newtonian mechanics to quantum field theory and cover several puzzling issues that do not appear in standard textbooks. Some topics cover conceptual conundrums, the solutions to which lead to surprising insights; some correct popular misconceptions in the textbook discussion of certain topics; others illustrate deep connections between apparently unconnected domains of theoretical physics; and a few provide remarkably simple derivations of results which are not often appreciated. The connoisseur of theoretical physics will enjoy a feast of pleasant surprises skilfully prepared by an internationally acclaimed theoretical physicist. Each topic is introduced with proper background discussion and special effort is taken to make the discussion self-contained, clear and comprehensible to anyone with an undergraduate e...

  16. Insights into Chromatin Structure and Dynamics in Plants

    Directory of Open Access Journals (Sweden)

    Stefanie Rosa

    2013-11-01

    Full Text Available The packaging of chromatin into the nucleus of a eukaryotic cell requires an extraordinary degree of compaction and physical organization. In recent years, it has been shown that this organization is dynamically orchestrated to regulate responses to exogenous stimuli as well as to guide complex cell-type-specific developmental programs. Gene expression is regulated by the compartmentalization of functional domains within the nucleus, by distinct nucleosome compositions accomplished via differential modifications on the histone tails and through the replacement of core histones by histone variants. In this review, we focus on these aspects of chromatin organization and discuss novel approaches such as live cell imaging and photobleaching as important tools likely to give significant insights into our understanding of the very dynamic nature of chromatin and chromatin regulatory processes. We highlight the contribution plant studies have made in this area showing the potential advantages of plants as models in understanding this fundamental aspect of biology.

  17. Insights on PRA Review Practices: Necessity for Model Shaking

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Inn Seock; Jang, Mi suk; Kim, Seoung Rae [NESS, Daejeon (Korea, Republic of)

    2016-05-15

    Probabilistic risk assessment (PRA) is increasingly used as a technique to help ensure design and operational safety of nuclear power plants (NPPs) in the nuclear industry. Hence, there is considerable interest in the PRA quality, and as a result, a peer review of the PRA model is typically performed to ensure its technical adequacy as part of the PRA development process or for any other reason (e.g., regulatory requirement). For the PRA model to be used as a valuable vehicle for risk-informed applications, it is essential that the PRA model must yield correct and physically meaningful accident sequences and minimal cutsets for specific plant configurations or conditions relating to the applications. Hence, the existing peer review guidelines need to be updated to reflect these insights so that risk-informed applications could be more actively pursued with confidence.

  18. Evolutionary insights into scleractinian corals using comparative genomic hybridizations.

    KAUST Repository

    Aranda, Manuel; DeSalvo, Michael K; Bayer, Till; Medina, Monica; Voolstra, Christian R.

    2012-01-01

    Coral reefs belong to the most ecologically and economically important ecosystems on our planet. Yet, they are under steady decline worldwide due to rising sea surface temperatures, disease, and pollution. Understanding the molecular impact of these stressors on different coral species is imperative in order to predict how coral populations will respond to this continued disturbance. The use of molecular tools such as microarrays has provided deep insight into the molecular stress response of corals. Here, we have performed comparative genomic hybridizations (CGH) with different coral species to an Acropora palmata microarray platform containing 13,546 cDNA clones in order to identify potentially rapidly evolving genes and to determine the suitability of existing microarray platforms for use in gene expression studies (via heterologous hybridization).

  19. CRISPR-Cas adaptation: insights into the mechanism of action.

    Science.gov (United States)

    Amitai, Gil; Sorek, Rotem

    2016-02-01

    Since the first demonstration that CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against phages and plasmids, numerous studies have yielded key insights into the molecular mechanisms governing how these systems attack and degrade foreign DNA. However, the molecular mechanisms underlying the adaptation stage, in which new immunological memory is formed, have until recently represented a major unresolved question. In this Progress article, we discuss recent discoveries that have shown both how foreign DNA is identified by the CRISPR-Cas adaptation machinery and the molecular basis for its integration into the chromosome to form an immunological memory. Furthermore, we describe the roles of each of the specific CRISPR-Cas components that are involved in memory formation, and consider current models for their evolutionary origin.

  20. Structural insights into the intertwined dimer of fyn SH2.

    Science.gov (United States)

    Huculeci, Radu; Garcia-Pino, Abel; Buts, Lieven; Lenaerts, Tom; van Nuland, Nico

    2015-12-01

    Src homology 2 domains are interaction modules dedicated to the recognition of phosphotyrosine sites incorporated in numerous proteins found in intracellular signaling pathways. Here we provide for the first time structural insight into the dimerization of Fyn SH2 both in solution and in crystalline conditions, providing novel crystal structures of both the dimer and peptide-bound structures of Fyn SH2. Using nuclear magnetic resonance chemical shift analysis, we show how the peptide is able to eradicate the dimerization, leading to monomeric SH2 in its bound state. Furthermore, we show that Fyn SH2's dimer form differs from other SH2 dimers reported earlier. Interestingly, the Fyn dimer can be used to construct a completed dimer model of Fyn without any steric clashes. Together these results extend our understanding of SH2 dimerization, giving structural details, on one hand, and suggesting a possible physiological relevance of such behavior, on the other hand. © 2015 The Protein Society.

  1. The face and person perception: insights from social cognition.

    Science.gov (United States)

    Quinn, Kimberly A; Macrae, C Neil

    2011-11-01

    Social-cognitive investigations of face perception have tended to be motivated by different goals than cognitive and neuropsychological studies-namely, to understand the dynamics of social categorization rather than identity recognition-and the result has been a lack of cross-pollination of insights and ideas between the disciplines. We review the evidence from social cognition, with an eye to discussing how this work aligns with the Bruce and Young (1986) model of face recognition. Acknowledging the invaluable impact the model has exerted on our understanding of face recognition, we suggest that considering the bottom-up constraints of visual processing and the top-down influences of semantic knowledge will contribute to a more comprehensive understanding of face perception. ©2011 The British Psychological Society.

  2. Personal semantic memory: insights from neuropsychological research on amnesia.

    Science.gov (United States)

    Grilli, Matthew D; Verfaellie, Mieke

    2014-08-01

    This paper provides insight into the cognitive and neural mechanisms of personal semantic memory, knowledge that is specific and unique to individuals, by reviewing neuropsychological research on stable amnesia secondary to medial temporal lobe damage. The results reveal that personal semantic memory does not depend on a unitary set of cognitive and neural mechanisms. Findings show that autobiographical fact knowledge reflects an experience-near type of personal semantic memory that relies on the medial temporal lobe for retrieval, albeit less so than personal episodic memory. Additional evidence demonstrates that new autobiographical fact learning likely relies on the medial temporal lobe, but the extent to which remains unclear. Other findings show that retrieval of personal traits/roles and new learning of personal traits/roles and thoughts/beliefs are independent of the medial temporal lobe and thus may represent highly conceptual types of personal semantic memory that are stored in the neocortex. Published by Elsevier Ltd.

  3. New Insights into the Operating Voltage of Aqueous Supercapacitors.

    Science.gov (United States)

    Yu, Minghao; Lu, Yongzhuang; Zheng, Haibing; Lu, Xihong

    2018-03-12

    The main limitation of aqueous supercapacitors (SCs) lies in their narrow operating voltages, especially when compared with organic SCs. Fundamental understanding of factors relevant to the operating voltage helps providing guidance for the assembly of high-voltage aqueous SCs. In this regard, this concept analyzes the deciding factors for the operating voltage of aqueous SCs. Strategies applied to expand the operating voltage are summarized and discussed from the aspects of electrolyte, electrode, and asymmetric structure. Dynamic factors associated with water electrolysis and maximally using the available potential ranges of electrodes are particularly emphasized. Finally, other promising approaches that have not been explored and their challenges are also elaborated, hoping to provide more insights for the design of high-voltage aqueous SCs. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Evolutionary insights into scleractinian corals using comparative genomic hybridizations.

    KAUST Repository

    Aranda, Manuel

    2012-09-21

    Coral reefs belong to the most ecologically and economically important ecosystems on our planet. Yet, they are under steady decline worldwide due to rising sea surface temperatures, disease, and pollution. Understanding the molecular impact of these stressors on different coral species is imperative in order to predict how coral populations will respond to this continued disturbance. The use of molecular tools such as microarrays has provided deep insight into the molecular stress response of corals. Here, we have performed comparative genomic hybridizations (CGH) with different coral species to an Acropora palmata microarray platform containing 13,546 cDNA clones in order to identify potentially rapidly evolving genes and to determine the suitability of existing microarray platforms for use in gene expression studies (via heterologous hybridization).

  5. Pathogenesis of the Metabolic Syndrome: Insights from Monogenic Disorders

    Directory of Open Access Journals (Sweden)

    Rinki Murphy

    2013-01-01

    Full Text Available Identifying rare human metabolic disorders that result from a single-gene defect has not only enabled improved diagnostic and clinical management of such patients, but also has resulted in key biological insights into the pathophysiology of the increasingly prevalent metabolic syndrome. Insulin resistance and type 2 diabetes are linked to obesity and driven by excess caloric intake and reduced physical activity. However, key events in the causation of the metabolic syndrome are difficult to disentangle from compensatory effects and epiphenomena. This review provides an overview of three types of human monogenic disorders that result in (1 severe, non-syndromic obesity, (2 pancreatic beta cell forms of early-onset diabetes, and (3 severe insulin resistance. In these patients with single-gene defects causing their exaggerated metabolic disorder, the primary defect is known. The lessons they provide for current understanding of the molecular pathogenesis of the common metabolic syndrome are highlighted.

  6. Analytical insights into optimality and resonance in fish swimming

    Science.gov (United States)

    Kohannim, Saba; Iwasaki, Tetsuya

    2014-01-01

    This paper provides analytical insights into the hypothesis that fish exploit resonance to reduce the mechanical cost of swimming. A simple body–fluid fish model, representing carangiform locomotion, is developed. Steady swimming at various speeds is analysed using optimal gait theory by minimizing bending moment over tail movements and stiffness, and the results are shown to match with data from observed swimming. Our analysis indicates the following: thrust–drag balance leads to the Strouhal number being predetermined based on the drag coefficient and the ratio of wetted body area to cross-sectional area of accelerated fluid. Muscle tension is reduced when undulation frequency matches resonance frequency, which maximizes the ratio of tail-tip velocity to bending moment. Finally, hydrodynamic resonance determines tail-beat frequency, whereas muscle stiffness is actively adjusted, so that overall body–fluid resonance is exploited. PMID:24430125

  7. Cobalt 60 gamma irradiation current status, trends and insights

    International Nuclear Information System (INIS)

    Corley, John T.

    1998-01-01

    This paper discusses the current status, trends and insights into the continued, safe use of cobalt 60 gamma irradiation. Also presented are some of the many initiatives undertaken at MDS Nordion. Topics covered include our investment for the future supply of raw materials and the latest news from source production. Briefly presented are the tasks associated with the safe transport of cobalt 60 around the world. Discussed is cobalt 60 usage at the customer site; more specifically maintaining source integrity, source utilization and irradiator design trends. Highlighted are industry trends for North America, Europe and the rest of the world. Finally presented are the challenges and opportunities for the industry. Stressed in the paper is the need to work together

  8. Microbial genome-enabled insights into plant-microorganism interactions.

    Science.gov (United States)

    Guttman, David S; McHardy, Alice C; Schulze-Lefert, Paul

    2014-12-01

    Advances in genome-based studies on plant-associated microorganisms have transformed our understanding of many plant pathogens and are beginning to greatly widen our knowledge of plant interactions with mutualistic and commensal microorganisms. Pathogenomics has revealed how pathogenic microorganisms adapt to particular hosts, subvert innate immune responses and change host range, as well as how new pathogen species emerge. Similarly, culture-independent community profiling methods, coupled with metagenomic and metatranscriptomic studies, have provided the first insights into the emerging field of research on plant-associated microbial communities. Together, these approaches have the potential to bridge the gap between plant microbial ecology and plant pathology, which have traditionally been two distinct research fields.

  9. Generic safety insights for inspection of boiling water reactors

    International Nuclear Information System (INIS)

    Higgins, J.C.; Taylor, J.H.; Fresco, A.N.; Hillman, B.M.

    1987-01-01

    As the number of operating nuclear power plants (NPP) increases, safety inspection has increased in importance. However, precisely what is important, and what is not important? What should one focus inspection efforts on. Over the last two years Probabilistic Risk Assessment (PR) techniques have been developed to aid in the inspection process. Broad interest in generic PRA-based methods has arisen in the past year, since only about 25% of the US nuclear power plants have completed PRAs, and also, inspectors want PRA-based tools for these plants. This paper describes the BNL program to develop generic BWR PRA-based inspection insights or inspection guidance designed to be applied to plants without PRAs

  10. Molecular electronics: insight from first-principles transport simulations.

    Science.gov (United States)

    Paulsson, Magnus; Frederiksen, Thomas; Brandbyge, Mads

    2010-01-01

    Conduction properties of nanoscale contacts can be studied using first-principles simulations. Such calculations give insight into details behind the conductance that is not readily available in experiments. For example, we may learn how the bonding conditions of a molecule to the electrodes affect the electronic transport. Here we describe key computational ingredients and discuss these in relation to simulations for scanning tunneling microscopy (STM) experiments with C60 molecules where the experimental geometry is well characterized. We then show how molecular dynamics simulations may be combined with transport calculations to study more irregular situations, such as the evolution of a nanoscale contact with the mechanically controllable break-junction technique. Finally we discuss calculations of inelastic electron tunnelling spectroscopy as a characterization technique that reveals information about the atomic arrangement and transport channels.

  11. Enhancing the seismic margin review methodology to obtain risk insights

    International Nuclear Information System (INIS)

    Budnitz, R.J.

    1992-01-01

    This paper discusses methods for obtaining risk insights from the seismic margin review (SMR) methodology. The SMR methodology was originally developed in 1984-1987 with the objective of analyzing an individual nuclear power plant to ascertain whether the plant has the ability to withstand earthquakes substantially beyond the design-basis earthquake without suffering a core-damage accident. Recently, in the context of Nuclear Regulatory Commission's (NRC's) Individual Plant Evaluation for External Events (IPEEE) program, the SMR methodology has been developed further by NRC to allow plants to identify plant-specific vulnerabilities (in the IPEEE sense) to seismic events. The objective of these enhancements has been to provide a methodology for IPEEE seismic review that is substantially less expensive than a full-scope seismic PRA, but that achieves the IPEEE's vulnerability-search objectives. In this paper, the steps involved in the enhanced methodology are discussed

  12. Global Insights Based on the Multidimensional Energy Poverty Index (MEPI

    Directory of Open Access Journals (Sweden)

    Mark Howells

    2013-05-01

    Full Text Available Energy access metrics are needed to track the progress towards providing sustainable energy for all. This paper presents advancements in the development of the Multidimensional Energy Poverty Index (MEPI, as well as results and analysis for a number of developing countries. The MEPI is a composite index designed to shed light on energy poverty by assessing the services that modern energy provides. The index captures both the incidence and intensity of energy poverty. It provides valuable insights–allowing the analysis of determinants of energy poverty–and, subsequently insights into policy efficacy. Building on previous work, this paper presents results obtained as a result of both increased data availability and enhanced methodology. Specifically, this analysis (i includes an increased number of countries, and (ii tracks the evolution of energy poverty over time of energy poverty in selected countries is reported.

  13. Insights of genius imagery and creativity in science and art

    CERN Document Server

    Miller, Arthur I

    1996-01-01

    Here, distinguished science historian Arthur I. Miller delves into the connections between modern art and modern physics. He takes us on a wide-ranging study to demonstrate that scientists and artists have a common aim: a visual interpretation of both the visible and invisible aspects of nature. Along the way, we encounter the philosophy of mind and language, cognitive science and neurophysiology in our search for the origins and meaning of visual imagery. At a time when the media are overeager to portray science as a godless, dehumanising exercise undermining the very fabric of society, this sixth book by Professor Miller shows how scientists are struggling to understand nature, convince their peers, inform the public and deal with the reactions to their research. Thus, Insights of Genuis must interest everyone who cares about science and its place in our culture.

  14. Avian genomics lends insights into endocrine function in birds.

    Science.gov (United States)

    Mello, C V; Lovell, P V

    2018-01-15

    The genomics era has brought along the completed sequencing of a large number of bird genomes that cover a broad range of the avian phylogenetic tree (>30 orders), leading to major novel insights into avian biology and evolution. Among recent findings, the discovery that birds lack a large number of protein coding genes that are organized in highly conserved syntenic clusters in other vertebrates is very intriguing, given the physiological importance of many of these genes. A considerable number of them play prominent endocrine roles, suggesting that birds evolved compensatory genetic or physiological mechanisms that allowed them to survive and thrive in spite of these losses. While further studies are needed to establish the exact extent of avian gene losses, these findings point to birds as potentially highly relevant model organisms for exploring the genetic basis and possible therapeutic approaches for a wide range of endocrine functions and disorders. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Electrochemical Insights into Platinum Catalysts for Fuel Cells

    DEFF Research Database (Denmark)

    Jensen, Kim Degn

    . A preliminary electrochemical study of in-house synthesized Pt-Y nanoparticles have also been presented revealing specific mass actives of 0.3 ± 0.1A/mgPt in HClO4. The study revealed that extensive optimizations of the Pt-Y nanoparticles are required and their performance is severely impeded by poor......Development of sustainable energy production, conversion and storage technologies must be considered one of the major challenges of the 21st century. Insight and understanding of the oxygen reduction reaction is imperative in these pursuits. In this work electrochemical investigations and physical...... characterization of various model systems ranging from extended surfaces, to thin films and nanoparticle electrocatalysts have been presented and discussed. This have been done with a special focus on governing factors controlling the electroreduction of oxygen. Preparation of Cu/Pt(111) near-surface alloys...

  16. Biological Actions of Artemisinin: Insights from Medicinal Chemistry Studies

    Directory of Open Access Journals (Sweden)

    Jian Li

    2010-03-01

    Full Text Available Artemisinins have become essential antimalarial drugs for increasingly widespread drug-resistant malaria strains. Although tremendous efforts have been devoted to decipher how this class of molecules works, their exact antimalarial mechanism is still an enigma. Several hypotheses have been proposed to explain their actions, including alkylation of heme by carbon-centered free radicals, interference with proteins such as the sarcoplasmic/endoplasmic calcium ATPase (SERCA, as well as damaging of normal mitochondrial functions. Besides artemisinins, other endoperoxides with various backbones have also been synthesized, some of which showed comparable or even higher antimalarial effects. It is noteworthy that among these artemisinin derivatives, some enantiomers displayed similar in vitro malaria killing efficacy. In this article, the proposed mechanisms of action of artemisinins are reviewed in light of medicinal chemistry findings characterized by efficacy-structure studies, with the hope of gaining more insight into how these potent drugs work.

  17. Insights from 20 years of bacterial genome sequencing

    DEFF Research Database (Denmark)

    Land, Miriam; Hauser, Loren; Jun, Se-Ran

    2015-01-01

    Since the first two complete bacterial genome sequences were published in 1995, the science of bacteria has dramatically changed. Using third-generation DNA sequencing, it is possible to completely sequence a bacterial genome in a few hours and identify some types of methylation sites along...... the genome as well. Sequencing of bacterial genome sequences is now a standard procedure, and the information from tens of thousands of bacterial genomes has had a major impact on our views of the bacterial world. In this review, we explore a series of questions to highlight some insights that comparative...... genomics has produced. To date, there are genome sequences available from 50 different bacterial phyla and 11 different archaeal phyla. However, the distribution is quite skewed towards a few phyla that contain model organisms. But the breadth is continuing to improve, with projects dedicated to filling...

  18. The Thermodynamics of Internal Combustion Engines: Examples of Insights

    Directory of Open Access Journals (Sweden)

    Jerald A. Caton

    2018-05-01

    Full Text Available A major goal of the development of internal combustion (IC engines continues to be higher performance and efficiencies. A major aspect of achieving higher performance and efficiencies is based on fundamental thermodynamics. Both the first and second laws of thermodynamics provide strategies for and limits to the thermal efficiencies of engines. The current work provides three examples of the insights that thermodynamics provides to the performance and efficiencies of an IC engine. The first example evaluates low heat rejection engine concepts, and, based on thermodynamics, demonstrates the difficulty of this concept for increasing efficiencies. The second example compares and contrasts the thermodynamics associated with external and internal exhaust gas dilution. Finally, the third example starts with a discussion of the Otto cycle analysis and explains why this is an incorrect model for the IC engine. An important thermodynamic property that is responsible for many of the observed effects is specific heat.

  19. Pathophysiology of Degenerative Mitral Regurgitation: New 3-Dimensional Imaging Insights.

    Science.gov (United States)

    Antoine, Clemence; Mantovani, Francesca; Benfari, Giovanni; Mankad, Sunil V; Maalouf, Joseph F; Michelena, Hector I; Enriquez-Sarano, Maurice

    2018-01-01

    Despite its high prevalence, little is known about mechanisms of mitral regurgitation in degenerative mitral valve disease apart from the leaflet prolapse itself. Mitral valve is a complex structure, including mitral annulus, mitral leaflets, papillary muscles, chords, and left ventricular walls. All these structures are involved in physiological and pathological functioning of this valvuloventricular complex but up to now were difficult to analyze because of inherent limitations of 2-dimensional imaging. The advent of 3-dimensional echocardiography, computed tomography, and cardiac magnetic resonance imaging overcoming these limitations provides new insights into mechanistic analysis of degenerative mitral regurgitation. This review will detail the contribution of quantitative and qualitative dynamic analysis of mitral annulus and mitral leaflets by new imaging methods in the understanding of degenerative mitral regurgitation pathophysiology. © 2018 American Heart Association, Inc.

  20. A hundred-year-old insight into the gut microbiome!

    Science.gov (United States)

    Aziz, Ramy Karam

    2009-12-07

    As the National Institutes of Health-funded Human Microbiome Project enters its second phase, and as a major part of this project focuses on the human gut microbiome and its effects on human health, it might help us to travel a century back in time and examine how microbiologists dealt with microbiome-related challenges similar to those of the 21st century using the tools of their time. An article by Arthur I. Kendall, published in The Journal of Biological Chemistry in November 1909 (Some observations on the study of the intestinal bacteria J Biol Chem 1909, 6:499-507), offers a visionary insight into many of today's hot research questions.

  1. Delbruck Prize Award: Insights into HIV Dynamics and Cure

    Science.gov (United States)

    Perelson, Alan S.

    A large effort is being made to find a means to cure HIV infection. I will present a dynamical model of a phenomenon called post-treatment control (PTC) or functional cure of HIV-infection in which some patients treated with suppressive antiviral therapy have been taken off of therapy and then spontaneously control HIV infection. The model relies on an immune response and bistability to explain PTC. I will then generalize the model to explicitly include immunotherapy with monoclonal antibodies approved for use in cancer to show that one can induce PTC with a limited number of antibody infusions and compare model predictions with experiments in SIV infected macaques given immunotherapy. Lastly, I will argue that quantitative insights derived from models of HIV infection have and will continue to play an important role in medicine.

  2. Social Motor Synchronization: Insights for Understanding Social Behavior in Autism.

    Science.gov (United States)

    Fitzpatrick, Paula; Romero, Veronica; Amaral, Joseph L; Duncan, Amie; Barnard, Holly; Richardson, Michael J; Schmidt, R C

    2017-07-01

    Impairments in social interaction and communication are critical features of ASD but the underlying processes are poorly understood. An under-explored area is the social motor synchronization that happens when we coordinate our bodies with others. Here, we explored the relationships between dynamical measures of social motor synchronization and assessments of ASD traits. We found (a) spontaneous social motor synchronization was associated with responding to joint attention, cooperation, and theory of mind while intentional social motor synchronization was associated with initiating joint attention and theory of mind; and (b) social motor synchronization was associated with ASD severity but not fully explained by motor problems. Findings suggest that objective measures of social motor synchronization may provide insights into understanding ASD traits.

  3. New insights into Prevotella diversity and medical microbiology.

    Science.gov (United States)

    Alauzet, Corentine; Marchandin, Hélène; Lozniewski, Alain

    2010-11-01

    In light of recent studies based on cultivation-independent methods, it appears that the diversity of Prevotella in human microbiota is greater than was previously assumed from cultivation-based studies, and that the implication of these bacteria in several human diseases was unrecognized. While some Prevotella taxa were found during opportunistic infections, changes in Prevotella abundance and diversity were discovered during dysbiosis-associated diseases. As member of the microbiota, Prevotella may also be considered as a reservoir for resistance genes. Greater knowledge on Prevotella diversity, as well as new insights into its pathogenic potential and implication in dysbiosis are expected from the use of human microbe identification microarrays, from whole-genome sequence analyse, and from the NIH Human Microbiome Project data. New approaches, including molecular-based methods, could contribute to improve the diagnosis of Prevotella infections.

  4. Water use data to enhance scientific and policy insight

    Science.gov (United States)

    Konar, M.

    2017-12-01

    We live in an era of big data. However, water use data remains sparse. There is an urgent need to enhance both the quality and resolution of water data. Metered water use information - as opposed to estimated water use, typically based on climate - would enhance the quality of existing water databases. Metered water use data would enable the research community to evaluate the "who, where, and when" of water use. Importantly, this information would enable the scientific community to better understand decision making related to water use (i.e. the "why"), providing the insight necessary to guide policies that promote water conservation. Metered water use data is needed at a sufficient resolution (i.e. spatial, temporal, and water user) to fully resolve how water is used throughout the economy and society. Improving the quality and resolution of water use data will enable scientific understanding that can inform policy.

  5. Insights from human genetic studies of lung and organ fibrosis.

    Science.gov (United States)

    Garcia, Christine Kim

    2018-01-02

    Genetic investigations of fibrotic diseases, including those of late onset, often yield unanticipated insights into disease pathogenesis. This Review focuses on pathways underlying lung fibrosis that are generalizable to other organs. Herein, we discuss genetic variants subdivided into those that shorten telomeres, activate the DNA damage response, change resident protein expression or function, or affect organelle activity. Genetic studies provide a window into the downstream cascade of maladaptive responses and pathways that lead to tissue fibrosis. In addition, these studies reveal interactions between genetic variants, environmental factors, and age that influence the phenotypic spectrum of disease. The discovery of forces counterbalancing inherited risk alleles identifies potential therapeutic targets, thus providing hope for future prevention or reversal of fibrosis.

  6. Optical studies of boiling heat transfer: insights and limitations

    International Nuclear Information System (INIS)

    Kenning, David B.R.

    2004-01-01

    Optical studies provide valuable insights into the complex mechanisms of boiling heat transfer but the large gradients of temperature (and therefore of refractive index) deflect light and multiple reflections at interfaces limit the distance over which observations can be made. Optical measurements are thought of as non-intrusive but this is rarely true. Because they are difficult and time consuming, they constrain the design of boiling experiments and are applied to limited ranges of conditions. There is a risk that deductions from the observations will be applied (not necessarily by the authors) more generally than is justified. These characteristics of optical studies are illustrated by examples from forced convective film boiling on spheres and pool nucleate boiling

  7. New insights into innate immune control of systemic candidiasis

    Science.gov (United States)

    Lionakis, Michail S.

    2014-01-01

    Systemic infection caused by Candida species is the fourth leading cause of nosocomial bloodstream infection in modern hospitals and carries high morbidity and mortality despite antifungal therapy. A recent surge of immunological studies in the mouse models of systemic candidiasis and the parallel discovery and phenotypic characterization of inherited genetic disorders in antifungal immune factors that are associated with enhanced susceptibility or resistance to the infection have provided new insights into the cellular and molecular basis of protective innate immune responses against Candida. In this review, the new developments in our understanding of how the mammalian immune system responds to systemic Candida challenge are synthesized and important future research directions are highlighted. PMID:25023483

  8. Current insights into hormonal regulation of microspore embryogenesis

    Directory of Open Access Journals (Sweden)

    Iwona eŻur

    2015-06-01

    Full Text Available Plant growth regulator (PGR crosstalk and interaction with the plant’s genotype and environmental factors play a crucial role in microspore embryogenesis (ME, controlling microspore-derived embryo differentiation and development as well as haploid/doubled haploid plant regeneration. The complexity of the PGR network which could exist at the level of biosynthesis, distribution, gene expression or signaling pathways, renders the creation of an integrated model of ME-control crosstalk impossible at present. However, the analysis of the published data together with the results received recently with the use of modern analytical techniques brings new insights into hormonal regulation of this process. This review presents a short historical overview of the most important milestones in the recognition of hormonal requirements for effective ME in the most important crop plant species and complements it with new concepts that evolved over the last decade of ME studies.

  9. Senescence gives insights into the morphogenetic evolution of anamniotes

    Directory of Open Access Journals (Sweden)

    Éric Villiard

    2017-06-01

    Full Text Available Senescence represents a mechanism to avoid undesired cell proliferation that plays a role in tumor suppression, wound healing and embryonic development. In order to gain insight on the evolution of senescence, we looked at its presence in developing axolotls (urodele amphibians and in zebrafish (teleost fish, which are both anamniotes. Our data indicate that cellular senescence is present in various developing structures in axolotls (pronephros, olfactory epithelium of nerve fascicles, lateral organs, gums and in zebrafish (epithelium of the yolk sac and in the lower part of the gut. Senescence was particularly associated with transient structures (pronephros in axolotls and yolk sac in zebrafish suggesting that it may play a role in the elimination of these tissues. Our data supports the notion that cellular senescence evolved early in vertebrate evolution to influence embryonic development.

  10. Optimal experience among teachers: new insights into the work paradox.

    Science.gov (United States)

    Bassi, Marta; Delle Fave, Antonella

    2012-01-01

    Several studies highlighted that individuals perceive work as an opportunity for flow or optimal experience, but not as desirable and pleasant. This finding was defined as the work paradox. The present study addressed this issue among teachers from the perspective of self-determination theory, investigating work-related intrinsic and extrinsic motivation, as well as autonomous and controlled behavior regulation. In Study 1, 14 teachers were longitudinally monitored with Experience Sampling Method for one work week. In Study 2, 184 teachers were administered Flow Questionnaire and Work Preference Inventory, respectively investigating opportunities for optimal experience, and motivational orientations at work. Results showed that work-related optimal experiences were associated with both autonomous regulation and with controlled regulation. Moreover, teachers reported both intrinsic and extrinsic motivation at work, with a prevailing intrinsic orientation. Findings provide novel insights on the work paradox, and suggestions for teachers' well-being promotion.

  11. The Fog signaling pathway: Insights into signaling in morphogenesis

    Science.gov (United States)

    Manning, Alyssa J.; Rogers, Stephen L.

    2014-01-01

    Epithelia form the building blocks of many tissue and organ types. Epithelial cells often form a contiguous 2-dimensional sheet that is held together by strong adhesions. The mechanical properties conferred by these adhesions allow the cells to undergo dramatic three-dimensional morphogenetic movements while maintaining cell–cell contacts during embryogenesis and post-embryonic development. The Drosophila Folded gastrulation pathway triggers epithelial cell shape changes that drive gastrulation and tissue folding and is one of the most extensively studied examples of epithelial morphogenesis. This pathway has yielded key insights into the signaling mechanisms and cellular machinery involved in epithelial remodeling. In this review, we discuss principles of morphogenesis and signaling that have been discovered through genetic and cell biological examination of this pathway. We also consider various regulatory mechanisms and the system's relevance to mammalian development. We propose future directions that will continue to broaden our knowledge of morphogenesis across taxa. PMID:25127992

  12. Selecting Solar: Insights into Residential Photovoltaic (PV) Quote Variation

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, Carolyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-10-01

    Before investing in a system, a prospective PV customer must not only have initial concept 'buy in,' but also be able to evaluate the tradeoffs associated with different system parameters. Prospective customers might need to evaluate disparate costs for each system attribute by comparing multiple bids. The difficulty of making such an evaluation with limited information can create a cognitive barrier to proceeding with the investment. This analysis leverages recently available data from EnergySage, an online solar marketplace, to offer the first data-driven characterization of quote variation faced by prospective PV customers, lending early insight into the decisions customers face once they have initial buy-in.

  13. Arthropod evolution and development: recent insights from chelicerates and myriapods.

    Science.gov (United States)

    Leite, Daniel J; McGregor, Alistair P

    2016-08-01

    Research on arthropod genetics and development has added much to our understanding of animal evolution. While this work has mainly focused on insects, a growing body of research on the less studied myriapods and chelicerates is providing important new insights into arthropod genomics and development. Multiple chelicerate lineages have a high incidence of gene duplication, which is suggestive of large-scale and even whole genome duplications. Furthermore, the duplication and divergence of genes is associated with the evolution of appendage morphology and other phenotypes in chelicerates and myriapods. Recent studies of these arthropods have also helped to understand the evolution and development of segmented bodies. Further research on chelicerate and myriapod models as well as species from other orders of these subphyla has great potential to expand our understanding of the evolution of animal genomes and development. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Insights into bacteriophage application in controlling Vibrio species

    Directory of Open Access Journals (Sweden)

    Vengadesh Letchumanan

    2016-07-01

    Full Text Available Bacterial infections from various organisms including Vibrio sp. pose a serious hazard to humans in many forms from clinical infection to affecting the yield of agriculture and aquaculture via infection of livestock. Vibrio sp. is one of the main foodborne pathogens causing human infection and is also a common cause of losses in the aquaculture industry. Prophylactic and therapeutic usage of antibiotics has become the mainstay of managing this problem, however this in turn led to the emergence of multidrug resistant strains of bacteria in the environment; which has raised awareness of the critical need for alternative non antibiotic based methods of preventing and treating bacterial infections. Bacteriophages - viruses that infect and result in the death of bacteria – are currently of great interest as a highly viable alternative to antibiotics. This article provides an insight into bacteriophage application in controlling Vibrio species as well underlining the advantages and drawbacks of phage therapy.

  15. The multitasking organ: recent insights into skin immune function.

    Science.gov (United States)

    Di Meglio, Paola; Perera, Gayathri K; Nestle, Frank O

    2011-12-23

    The skin provides the first line defense of the human body against injury and infection. By integrating recent findings in cutaneous immunology with fundamental concepts of skin biology, we portray the skin as a multitasking organ ensuring body homeostasis. Crosstalk between the skin and its microbial environment is also highlighted as influencing the response to injury, infection, and autoimmunity. The importance of the skin immune network is emphasized by the identification of several skin-resident cell subsets, each with its unique functions. Lessons learned from targeted therapy in inflammatory skin conditions, such as psoriasis, provide further insights into skin immune function. Finally, we look at the skin as an interacting network of immune signaling pathways exemplified by the development of a disease interactome for psoriasis. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Electron Microscopy Structural Insights into CPAP Oligomeric Behavior

    DEFF Research Database (Denmark)

    Alvarez-Cabrera, Ana L; Delgado, Sandra; Gil-Carton, David

    2017-01-01

    Centrosomal P4.1-associated protein (CPAP) is a cell cycle regulated protein fundamental for centrosome assembly and centriole elongation. In humans, the region between residues 897-1338 of CPAP mediates interactions with other proteins and includes a homodimerization domain. CPAP mutations cause...... into clearly different regular 3D maps (putatively corresponding to dimers and tetramers) and direct observation of individual images representing other complexes of HsCPAP(897-1338) (i.e., putative flexible monomers and higher-order multimers), we report a dynamic oligomeric behavior of this protein, where...... of different oligomers of CPAP, suggesting further insights to understand how this protein works, contributing to the elucidation of control mechanisms for centriole biogenesis....

  17. Induced seismicity provides insight into why earthquake ruptures stop

    KAUST Repository

    Galis, Martin

    2017-12-21

    Injection-induced earthquakes pose a serious seismic hazard but also offer an opportunity to gain insight into earthquake physics. Currently used models relating the maximum magnitude of injection-induced earthquakes to injection parameters do not incorporate rupture physics. We develop theoretical estimates, validated by simulations, of the size of ruptures induced by localized pore-pressure perturbations and propagating on prestressed faults. Our model accounts for ruptures growing beyond the perturbed area and distinguishes self-arrested from runaway ruptures. We develop a theoretical scaling relation between the largest magnitude of self-arrested earthquakes and the injected volume and find it consistent with observed maximum magnitudes of injection-induced earthquakes over a broad range of injected volumes, suggesting that, although runaway ruptures are possible, most injection-induced events so far have been self-arrested ruptures.

  18. Phosphoproteomics by mass spectrometry: insights, implications, applications and limitations.

    Science.gov (United States)

    Mayya, Viveka; Han, David K

    2009-12-01

    Phosphorylation of proteins is a predominant, reversible post-translational modification. It is central to a wide variety of physiological responses and signaling mechanisms. Recent advances have allowed the global scope of phosphorylation to be addressed by mass spectrometry using phosphoproteomic approaches. In this perspective, we discuss four aspects of phosphoproteomics: the insights and implications from recently published phosphoproteomic studies and the applications and limitations of current phosphoproteomic strategies. Since approximately 50,000 known phosphorylation sites do not yet have any ascribed function, we present our perspectives on a major function of protein phosphorylation that may be of predictive value in hypothesis-based investigations. Finally, we discuss strategies to measure the stoichiometry of phosphorylation in a proteome-wide manner that is not provided by current phosphoproteomic approaches.

  19. New Insights on Neurobiological Mechanisms underlying Alcohol Addiction

    Science.gov (United States)

    Cui, Changhai; Noronha, Antonio; Morikawa, Hitoshi; Alvarez, Veronica A.; Stuber, Garret D.; Szumlinski, Karen K.; Kash, Thomas L.; Roberto, Marisa; Wilcox, Mark V.

    2012-01-01

    Alcohol dependence/addiction is mediated by complex neural mechanisms that involve multiple brain circuits and neuroadaptive changes in a variety of neurotransmitter and neuropeptide systems. Although recent studies have provided substantial information on the neurobiological mechanisms that drive alcohol drinking behavior, significant challenges remain in understanding how alcohol-induced neuroadaptations occur and how different neurocircuits and pathways cross-talk. This review article highlights recent progress in understanding neural mechanisms of alcohol addiction from the perspectives of the development and maintenance of alcohol dependence. It provides insights on cross talks of different mechanisms and reviews the latest studies on metaplasticity, structural plasticity, interface of reward and stress pathways, and cross-talk of different neural signaling systems involved in binge-like drinking and alcohol dependence. PMID:23159531

  20. Unicystic plexiform ameloblastoma: An insight for pediatric dentists

    Directory of Open Access Journals (Sweden)

    Yavagal C

    2009-03-01

    Full Text Available Ameloblastomas have been categorized broadly into three biologic variants: cystic (unicystic, solid, and peripheral. The term plexiform unicystic ameloblastoma refers to a pattern of epithelial proliferation that has been described in cystic lesions of the jaws. Although the histology suggests that cystic ameloblastomas follow a biologically low-grade course, recent evidence suggests that they may often behave clinically as biologically aggressive tumors. This is supported by the high incidence of cortical perforation, tooth resorption, lesion size, bony destruction, and a high rate of recurrence after simple enucleation. This article tries to provide an insight for pediatric dentists regarding this biologically distinct entity. A literature review on the topic has been added along with a case report highlighting the state-of-the-art approach and management of such ameloblastomas, in pediatric patients.