[Research progress on standards of commodity classes of Chinese materia medica and discussion on several key problems].

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Yang, Guang; Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Jin, Yan; Zheng, Yu-Guang; Wang, Yong-Yan

2014-05-01

Standards of commodity classes of Chinese materia medica is an important way to solve the "Lemons Problem" of traditional Chinese medicine market. Standards of commodity classes are also helpful to rebuild market mechanisms for "high price for good quality". The previous edition of commodity classes standards of Chinese materia medica was made 30 years ago. It is no longer adapted to the market demand. This article researched progress on standards of commodity classes of Chinese materia medica. It considered that biological activity is a better choice than chemical constituents for standards of commodity classes of Chinese materia medica. It is also considered that the key point to set standards of commodity classes is finding the influencing factors between "good quality" and "bad quality". The article also discussed the range of commodity classes of Chinese materia medica, and how to coordinate standards of pharmacopoeia and commodity classes. According to different demands, diversiform standards can be used in commodity classes of Chinese materia medica, but efficacy is considered the most important index of commodity standard. Decoction pieces can be included in standards of commodity classes of Chinese materia medica. The authors also formulated the standards of commodity classes of Notoginseng Radix as an example, and hope this study can make a positive and promotion effect on traditional Chinese medicine market related research.

[Construction of biopharmaceutics classification system of Chinese materia medica].

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Liu, Yang; Wei, Li; Dong, Ling; Zhu, Mei-Ling; Tang, Ming-Min; Zhang, Lei

2014-12-01

Based on the characteristics of multicomponent of traditional Chinese medicine and drawing lessons from the concepts, methods and techniques of biopharmaceutics classification system (BCS) in chemical field, this study comes up with the science framework of biopharmaceutics classification system of Chinese materia medica (CMMBCS). Using the different comparison method of multicomponent level and the CMMBCS method of overall traditional Chinese medicine, the study constructs the method process while setting forth academic thoughts and analyzing theory. The basic role of this system is clear to reveal the interaction and the related absorption mechanism of multicomponent in traditional Chinese medicine. It also provides new ideas and methods for improving the quality of Chinese materia medica and the development of new drug research.

Ten Steps to Improve Quality of the Journal Materia Socio-Medica.

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Donev, Doncho M; Masic, Izet

2017-03-01

Materia Socio-Medica is one of the oldest public health journals in Europe, established in 1978, and among the most important journals for public health in South-Eastern Europe. The Journal covers all important public health professional, academic and research areas in this field. The aim of the paper is to analyze the journal articles and statistical facts in 2016 and to point out the directions for action and planned further activities for improving the quality of the published papers and visibility of the journal. Review and analysis of documentation and production of the journal, evidence of submitted and rejected manuscripts and published papers in 2016. Total number of 111 articles was published in Materia Socio-Medica during 2016. The most of them were original articles (64,5%). Articles from the fields of Health promotion and prevention were predominant (82,7%), which is one of the primary scope of the journal. Authors of the published articles in 2016 are dispersed to three continents (Europe, Asia and North America) and 15 different countries. The largest number of articles was submitted by authors from the country of origin of the journal, Bosnia and Herzegovina. The acceptance rate of Materia Socioi-Medica in 2016 was 35.7%. Total number of 116 reviewers participated in the manuscript review process in 2016. Materia Socio-Medica will continue to improve the quality of the published papers in 2017 and beyond through education of potential authors, reviewers and Editorial Board members, quality selection of reviewers, supportive editing of articles, and clearly defining instructions and ethical standards of the journal.

[Study on differences between pharmacokinetics and chromatopharmacodynamics for Chinese materia medica formulae].

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He, Fuyuan; Deng, Kaiwen; Zou, Huan; Qiu, Yun; Chen, Feng; Zhou, Honghao

2011-01-01

To study on the differences between chromatopharmacokinetics (pharmacokinetics with fingerprint chromatography) and chromatopharmacodynamics (pharmacodynamics with fingerprint chromatography) of Chinese materia medica formulae to answer the question whether the pharmacokinetic parameters of multiple composites can be utilized to guide the medication of multiple composites. On the base of established four chromatopharmacology (pharmacology with chromatographic fingerprint), the pharmacokinetics, and pharmacodynamics were analyzed comparably on their mathematical model and parameter definition. On the basis of quantitative pharmacology, the function expressions and total statistical parameters, such as total zero moment, total first moment, total second moment of the pharmacokinetics, and pharmacodynamics were analyzed to the common expressions and elucidated results for single and multiple components in Chinese materia medica formulae. Total quantitative pharmacokinetic, i.e., chromatopharmacokinetic parameter were decided by each component pharmacokinetic parameters, whereas the total quantitative pharmacodynamic, i.e., chromatopharmacodynamic parameter were decided by both of pharmacokinetic and pharmacodynamic parameters of each components. The pharmacokinetic parameters were corresponded to pharmacodynamic parameters with an existing stable effective coefficient when the constitutive ratio of each composite was a constant. The effects of Chinese materia medica were all controlled by pharmacokinetic and pharmacodynamic coefficient. It is a special case that the pharmacokinetic parameter could independently guide the clinical medication for single component whereas the chromatopharmacokinetic parameters are not applied to the multiple drug combination system, and not be used to solve problems of chromatopharmacokinetic of Chinese materia medica formulae.

[Revision to origin of northern Artemisia argyi in Compendium of Materia Medica (Bencao gangmu)].

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Huang, Lu-qi; Qiu, Le

2014-12-01

The origin of northern Artemisia argyi recorded in Compendium of Materia Medica(Bencao gangmu) is Fudao(Chinese characters) in Tangyin county, While there is only Fudao(Chinese characters) instead of Fudao(Chinese characters). Whether indeed Fudao(Chinese characters) is Fudao(Chinese characters)? By reviewing the genuine evolution of A. argyi, doing textual research on Fudao(Chinese characters) and combing with field survey data of national census of Chinese Materia Medica resources, this paper concluded that the word Fudao(Chinese characters) firstly emerged in Figure Canon of Chinese Materia Medica(Bencao tujing) of Susong in Song dynasty and was applied in later generations, but the implication was not clear, then emerged both Tangyin and Fudao(Chinese characters) in Compendium of Materia Medica(Bencao gangmu). The place Fudao(Chinese characters) is one of the graves of Bianque, that existed from Shang and Zhou dynasty and never changed until now, the A. argyi of Tangyin was famous from the grave of Bianque in Fudao(Chinese characters), which could infer that Lishizhen considered Fudao (Chinese characters) was Fudao(Chinese characters) indeed, and the origin of northern A. argyi was Fudao(Chinese characters) in Tangyin county.

[Differences of bi-directional regulative effects between acu-moxibustion and Chinese materia medica interventions].

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Cao, Xin; Yu, Zhi; Xu, Bin

2012-10-01

Bi-directional regulation is referred to a balancing effect of both acu-moxibustion and Chinese materia medica interventions when the human body is experiencing a hyperactivity or hypoactivity due to abnormal intrinsic or external factors. In the present paper, the authors analyze their identical and different characteristics from: 1) definition; 2) characters of regulative effects of acu-moxibustion therapy: A) differentiation of meridian and zangfu-organs being the basis of treatment, B) four factors (acupoint-location, body's functional state, acupoint-formula and needle-manipulation techniques) dependant, C) entirety regulation, and D) centrotaxis modulation; 3) characters of Chinese materia medica intervention: including a) correspondence between the drug property and the syndrome being the basis of the regulative effect, b) multi-factors [components (antagonist and agonist), combination, dosages and processing quality of Chinese materia medica, and functional state of the human body] dependant, c) entirety regulation, and d) both centrotaxis and deviation adjustment. In one word, the bi-directional regulation effect is one of the basic characteristics of both acu-moxibustion and Chinese materia medica in clinical practice, but their basis and modes for inducing effects are different.

[Application of bioassay in quality control of Chinese materia medica-taking Radix Isatidis as an example].

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Yan, Dan; Ren, Yongshen; Luo, Jiaoyang; Li, Hanbing; Feng, Xue; Xiao, Xiaohe

2010-10-01

Bioassay, which construct the characteristics consistents with Chinese medical science, is the core mode and methods for the quality control of Chinese materia medica. Taking the bioassay of Radix Isatidis as an example, the contribution, status and application of bioassay in the quality control of Chinese materia medica were introduced in this article, and two key issue (the selection of reference and measurement methods) in the process of establishing bioassay were also explained. This article expects to provide a reference for the development and improvement of the bioassay of Chinese materia medica in a practical manipulation level.

A comparison of medicinal plant use in Sardinia and Sicily-De Materia Medica revisited?

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Leonti, Marco; Casu, Laura; Sanna, Francesca; Bonsignore, Leonardo

2009-01-21

Written records of oral medical traditions have had significant impact on the development of medicine and the pharmacopoeias. Modern ethnobotanical studies in Europe and the Mediterranean region, however, have so far largely overlooked the richness and accuracy of historic sources and ignored their probable influence on the development of today's local traditional medicines. Here, we explore the common fundament of traditional knowledge for the medicinal plant uses in Sardinia and Sicily by comparing the selection of medicinal species and specific uses with those of Dioscorides' De Materia Medica. We use (i) a quantification of citations for medicinal species mentioned in ethnobotanical studies conducted in Sardinia and Sicily (ii) a comparison of the flora and medicinal flora with a chi(2)-test (iii) a binomial approach recently introduced into ethnobotany (iv) a comparison of the most frequently used species with the indications cited in Dioscorides' De Materia Medica (v) and a crosscheck of all mentioned species with their appearance in Berendes' translation of De Materia Medica. We identified a core group of 170 medicinal species used on either islands, which accumulate 74% of all citations and are best represented in De Materia Medica. The 15 most frequently used species of both islands demonstrate intriguing parallels for indications with Dioscorides' work. The ethnopharmacopoeia of Sicily and Sardinia are shallow stereotypes of the different editions of De Materia Medica and talking of oral tradition in this respect is a contradiction. The medicinal species of Sardinia and Sicily are largely widespread and common species, including many weeds, which are not facing threat of extinction. Therefore, using traditional medicinal practices as an argument for conservation biology or vice versa is not scientifically sound.

[Data validation methods and discussion on Chinese materia medica resource survey].

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Zhang, Yue; Ma, Wei-Feng; Zhang, Xiao-Bo; Zhu, Shou-Dong; Guo, Lan-Ping; Wang, Xing-Xing

2013-07-01

From the beginning of the fourth national survey of the Chinese materia medica resources, there were 22 provinces have conducted pilots. The survey teams have reported immense data, it put forward the very high request to the database system construction. In order to ensure the quality, it is necessary to check and validate the data in database system. Data validation is important methods to ensure the validity, integrity and accuracy of census data. This paper comprehensively introduce the data validation system of the fourth national survey of the Chinese materia medica resources database system, and further improve the design idea and programs of data validation. The purpose of this study is to promote the survey work smoothly.

[The application of metabonomics in modern studies of Chinese materia medica].

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Chen, Hai-Bin; Zhou, Hong-Guang; Yu, Xiao-Yi

2012-06-01

Metabonomics, a newly developing subject secondary to genomics, transcriptomics, and proteomics, is an important constituent part of systems biology. It is believed to be the final direction of the systems biology. It can be directly applied to understand the physiological and biochemical states by its "metabolome profile" as a whole. Therefore, it can provide a huge amount of information different from those originating from other "omics". In the modernization of Chinese materia medica research, the application of metabonomics methods and technologies has a broad potential for future development. Especially it is of important theoretical significance and application value in holistic efficacies evaluation, active ingredients studies, and safety research of Chinese materia medica.

[Important application of intestinal transporters and metabolism enzymes on gastrointestinal disposal of active ingredients of Chinese materia medica].

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Bi, Xiaolin; Du, Qiu; Di, Liuqing

2010-02-01

Oral drug bioavailability depends on gastrointestinal absorption, intestinal transporters and metabolism enzymes are the important factors in drug gastrointestinal absorption and they can also be induced or inhibited by the active ingredients of Chinese materia medica. This article presents important application of intestinal transporters and metabolism enzymes on gastrointestinal disposal of the active ingredients of Chinese materia medica, and points out the importance of research on transport and metabolism of the active ingredients of Chinese materia medica in Chinese extract and Chinese medicinal formulae.

Identification of species and materia medica within Angelica L. (Umbelliferae) based on phylogeny inferred from DNA barcodes.

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Yuan, Qing-Jun; Zhang, Bin; Jiang, Dan; Zhang, Wen-Jing; Lin, Tsai-Yun; Wang, Nian-He; Chiou, Shu-Jiau; Huang, Lu-Qi

2015-03-01

DNA barcodes have been increasingly used in authentication of medicinal plants, while their wide application in materia medica is limited in their accuracy due to incomplete sampling of species and absence of identification for materia medica. In this study, 95 leaf accessions of 23 species (including one variety) and materia medica of three Pharmacopoeia-recorded species of Angelica in China were collected to evaluate the effectiveness of four DNA barcodes (rbcL, matK, trnH-psbA and ITS). Our results showed that ITS provided the best discriminatory power by resolving 17 species as monophyletic lineages without shared alleles and exhibited the largest barcoding gap among the four single barcodes. The phylogenetic analysis of ITS showed that Levisticum officinale and Angelica sinensis were sister taxa, which indicates that L. officinale should be considered as a species of Angelica. The combination of ITS + rbcL + matK + trnH-psbA performed slight better discriminatory power than ITS, recovering 23 species without shared alleles and 19 species as monophyletic clades in ML tree. Authentication of materia medica using ITS revealed that the decoction pieces of A. sinensis and A. biserrata were partially adulterated with those of L. officinale, and the temperature around 80 °C processing A. dahurica decoction pieces obviously reduced the efficiency of PCR and sequencing. The examination of two cultivated varieties of A. dahurica from different localities indicated that the four DNA barcodes are inefficient for discriminating geographical authenticity of conspecific materia medica. This study provides an empirical paradigm in identification of medicinal plants and their materia medica using DNA barcodes. © 2014 The Authors. Molecular Ecology Resources Published by John Wiley & Sons Ltd.

[Essential procedure and key methods for survey of traditional knowledge related to Chinese materia medica resources].

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Cheng, Gong; Huang, Lu-qi; Xue, Da-yuan; Zhang, Xiao-bo

2014-12-01

The survey of traditional knowledge related to Chinese materia medica resources is the important component and one of the innovative aspects of the fourth national survey of the Chinese materia medica resources. China has rich traditional knowledge of traditional Chinese medicine (TCM) and the comprehensive investigation of TCM traditional knowledge aims to promote conservation and sustainable use of Chinese materia medica resources. Building upon the field work of pilot investigations, this paper introduces the essential procedures and key methods for conducting the survey of traditional knowledge related to Chinese materia medica resources. The essential procedures are as follows. First is the preparation phrase. It is important to review all relevant literature and provide training to the survey teams so that they have clear understanding of the concept of traditional knowledge and master key survey methods. Second is the field investigation phrase. When conducting field investigations, survey teams should identify the traditional knowledge holders by using the 'snowball method', record the traditional knowledge after obtaining prior informed concerned from the traditional knowledge holders. Researchers should fill out the survey forms provided by the Technical Specification of the Fourth National Survey of Chinese Materia Medica Resources. Researchers should pay particular attention to the scope of traditional knowledge and the method of inheriting the knowledge, which are the key information for traditional knowledge holders and potential users to reach mutual agreed terms to achieve benefit sharing. Third is the data compilation and analysis phrase. Researchers should try to compile and edit the TCM traditional knowledge in accordance with intellectual property rights requirements so that the information collected through the national survey can serve as the basic data for the TCM traditional knowledge database. The key methods of the survey include regional

[History and development of carbonization of Chinese materia medica and exploration on its mechanism of hemostatic action].

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He, R J; Diao, T M; DU, D

2017-03-28

The first material recorded about hair charcoal is seen in Nei jing ( Inner Canon ). It has a history of over 2 000 years for the carbonization of Chinese materia medica. There were controversies on this matter and its clinical application was seldom seen and underdeveloped. After the Yuan Dynasty, the main theory of carbonic herbs for hemostasis, and keeping the nature of the medicines after carbonization was gradually formed, and physicians of generations began to conduct in-depth research. Through repeated practice and verification, people summed up the suitable species of Chinese materia medica and its principle for carbonization. The methods and degree of carbonization of Chinese materia medica are reasonably discussed, with its principle and basis for application primarily interpreted.

[Preliminary investigation on the materia medica of the Zhuang ethnic group].

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Rong, Xiao-Xiang; Li, Gui

2013-09-01

By Zhuang materia medica, it refers to application of medicines under the instructions of medical theory of Zhuang ethnic group. By studying the pronunciation of the Zhuang language for the terms "zhu yu", "bai jiu", and "mi gu" included in the shan hai jing nan shan jing (The Classic of Southern Mountain in Classic of Seas and Mountains) carried out by the Zhuang scholar Qin Bao-lin, it was concluded that the Zhuang minority already applied medicines early in the pre-Qin period. Through extensive cultural communication in different regions in the Wei-Jin-Southern-Northern Dynasties, the medicinal experiences of the Zhuang ethnic group appeared in ancient literature. The antidotes in Zhou hou fang (Handbook of Prescriptions for Emergency), for instance, were mostly coming from the Southern Ridge area. Since the Sui-Tang Dynasties, many materia medica recorded in the herbal works and regional gazetteers, and Annals such as the Guangxi Annals, Gazetteer of Nanning County, and Gazetteer of Liuzhou County, Gazetteer of Binzhou County etc., also carry medicines such as Cinnamom twigs and bark, and mangosteen etc., which are similar to those of the Zhuang medicines. In the Republican period, many manuscripts of Zhuang medicines appeared. After 1949, many institutions of Zhuang medicine were set up successively, including The Nanning Medical Institute, The Medical Institute of Wuzhou, The Medical Institute of Guilin. Systematic researches were also done, with publication of a series of works on Zhuang materia medica. Reformation of part of the prescription forms of Zhuang medicine were also accomplished.

[Suitable investigation method of exploration and suggestions for investigating Chinese materia medica resources from wetland and artificial water of Hongze Lake region].

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Liu, Rui; Yan, Hui; Duan, Jin-Ao; Liu, Xing-Jian; Ren, Quan-Jin; Li, Hui-Wei; Bao, Bei-Hua; Zhang, Zhao-Hui

2016-08-01

According to the technology requirements of the fourth national survey of Chinese Materia Medica resources (pilot), suitable investigation method of exploration and suggestions for investigating Chinese Materia Medica resources was proposed based on the type of wetland and artificial water of Hongze Lake region. Environment of Hongze Lake and overview of wetland, present situation of ecology and vegetation and vegetation distribution were analyzed. Establishment of survey plan, selection of sample area and sample square and confirmation of representative water area survey plan were all suggested. The present study provide references for improving Chinese materia medica resources survey around Hongze Lake, and improving the technical specifications. It also provide references for investigating Chinese Materia Medica resources survey on similar ecological environment under the condition of artificial intervention. Copyright© by the Chinese Pharmaceutical Association.

[Investigation on pattern of quality control for Chinese materia medica based on famous-region drug and bioassay--the work reference].

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Yan, Dan; Xiao, Xiaohe

2011-05-01

Selection and standardization of the work reference are the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis. as an example, the manufacture process of the famous-region drugs extraction was explained from the aspects of original identification, routine examination, component analysis and bioassay. The common technologies were extracted, and the selection and standardization procedures of the work reference for the bioassay of Chinese materia medica were drawn up, so as to provide technical support for constructing a new mode and method of the quality control of Chinese materia medica based on the famous-region drugs and bioassay.

[Recent advances of synthetic biology for production of functional ingredients in Chinese materia medica].

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Su, Xin-Yao; Xue, Jian-Ping; Wang, Cai-Xia

2016-11-01

The functional ingredients in Chinese materia medica are the main active substance for traditional Chinese medicine and most of them are secondary metabolites derivatives. Until now,the main method to obtain those functional ingredients is through direct extraction from the Chinese materia medica. However, the income is very low because of the high extraction costs and the decreased medicinal plants. Synthetic biology technology, as a new and microbial approach, can be able to carry out large-scale production of functional ingredients and greatly ease the shortage of traditional Chinese medicine ingredients. This review mainly focused on the recent advances in synthetic biology for the functional ingredients production. Copyright© by the Chinese Pharmaceutical Association.

[The translation and its meanings of Materia Medica Part. I in the Jejungwon].

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Park, Junhyoung; Park, Hyoungwoo

2011-12-31

For more systematic medical education, Dr. O. R. Avison translated medical textbooks into Korean since he took charge of Jejungwon in 1893. The first book he chose was Anatomy of the Human Body. He, however, failed to see it published after losing its manuscript twice. Instead, Materia Medica Part. I was brought into the world first in 1905, for which he translated Materia Medica and Therapeutics written by John Mitchell Bruce from the U. K. At that time, this book was in widespread use in the English-speaking world as a textbook for pharmacology. It is also assumed that Avison used it as a textbook for his classes in Canada before coming to Korea. For the publication of Materia Medica Part. I, Avison did not translate Bruce's original text in full, but translated only the selected passages. He followed a principle of using Korean alphabets (Hangeul) only, but in combination with Chinese characters, if necessary. He put pharmacological terms into existing Korean equivalents or newly coined words, but also borrowed many from Japanese terms. That's because Japan moved faster to introduce Western medicine than Korea did, so that many pharmacological terms could be defined and arranged more systematically in Japanese. Moreover, Japan took such a favorable stance in the state of international affairs that many of Japanese-style terms could be introduced into Korea in most fields including medicine. By translating Materia Medica Part. I in cooperation with his disciple KIM Pilsoon after Gray's Anatomy of the Human Body, Avison tried to lay groundwork for providing medical education in Korea based on the British-American medicine. It is assumed that he took an independent stance in selecting and translating Western medical textbooks on his own rather than simply accepting the existing Chinese translation of Western medical textbooks. Despite all his efforts, he might find it difficult to translate all the Western medical terms into Korean within a short period of time

[Principles for molecular identification of traditional Chinese materia medica using DNA barcoding].

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Chen, Shi-Lin; Yao, Hui; Han, Jian-Ping; Xin, Tian-Yi; Pang, Xiao-Hui; Shi, Lin-Chun; Luo, Kun; Song, Jing-Yuan; Hou, Dian-Yun; Shi, Shang-Mei; Qian, Zhong-Zhi

2013-01-01

Since the research of molecular identification of Chinese Materia Medica (CMM) using DNA barcode is rapidly developing and popularizing, the principle of this method is approved to be listed in the Supplement of the Pharmacopoeia of the People's Republic of China. Based on the study on comprehensive samples, the DNA barcoding systems have been established to identify CMM, i.e. ITS2 as a core barcode and psbA-trnH as a complementary locus for identification of planta medica, and COI as a core barcode and ITS2 as a complementary locus for identification of animal medica. This article introduced the principle of molecular identification of CMM using DNA barcoding and its drafting instructions. Furthermore, its application perspective was discussed.

[Four properties law of nature data of Chinese materia medica in "Chinese herbal medicine (CHM)"].

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Yang, Xue-Mei; Lin, Duan-Yi; Lai, Xin-Mei; Chen, Mei-Mei; Huang, Lu-Qi

2013-05-01

In order to provide theoretical clues and data support for the use of Chinese medicine clinical drug, experimental study of Chinese materia medica and development of new resources of Chinese materia medica, the four properties as the core, the relationships of property, flavor, channel tropism and toxicity in nature data of Chinese materia medica were analyzed. The spearman rank correlation method was employed to analyze 8 356 Chinese drugs with characteristic of four properties from " Chinese Herbal Medicine" based on data level coding. It was discovered that four properties showed significant positive correlations with tastes of "pungent and sweet" , channels of "spleen" , "stomach" , "kidney" and "toxicity" , but also showed significant negative correlations with tastes of "bitter" and "light" and six channels such as "large intestine" , "heart", "bladder" , "gallbladder" , "small intestine" and "lung" (in descending order of correlation ) (P <0. 01). It was indicated that the more hot the Chinese medicine nature, the more possible it contained "toxicity" , tastes of "pungent" and "sweet" , and the more possible it was belong to channels of "spleen" , "stomach" and "kidney". As well, the more cold the Chinese medicine nature, the more possible it contained tastes of "bitter" and "light", and the more possible it was belong to six channels such as "large intestine", etc.

Review of adverse reactions to injections of Chinese materia medica.

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Bian, Zhaoxiang; Shang, Hongcai; Cheng, Chungwah; Wu, Taixiang; Li, Youping; Zhang, Boli

2010-05-01

Using Chinese Materia Medica (CM) as injections is an innovation that is proving effective in extensive clinical use in Mainland China. However, recent reports have focused on adverse reactions, ignoring the considerable successes of these preparations. In order to achieve balance in the media and in the minds of the public, we suggest the first step is to clarify the concepts of and differences between adverse drug reactions (ADR) and adverse events (AE) for all concerned-the public, medical practitioners, government officials, and lawmakers. Second, the State Food and Drug Administration should raise the requirements for Chinese Materia Medica Injection (CMI) registration and license approval and emphasize the importance of evidence-based CMI development and evidence-based CMI license approval. Thirdly, drug companies and institutions should reinforce basic research about the quality control of herbs and CMI-drug interactions. Fourth, the Government should clarify the legal responsibilities for CMI approval agencies, CMI developers, medical doctors, and patients. Fifth, the medical association and Government should enhance training for health care professionals concerning the usage of CMIs. And finally sixth, State Food and Drug Administration should monitor the content and quality of the directions for use of CMI. © 2010 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

[Study on biopharmaceutics classification system for Chinese materia medica of extract of Huanglian].

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Liu, Yang; Yin, Xiu-Wen; Wang, Zi-Yu; Li, Xue-Lian; Pan, Meng; Li, Yan-Ping; Dong, Ling

2017-11-01

One of the advantages of biopharmaceutics classification system of Chinese materia medica (CMMBCS) is expanding the classification research level from single ingredient to multi-components of Chinese herb, and from multi-components research to holistic research of the Chinese materia medica. In present paper, the alkaloids of extract of huanglian were chosen as the main research object to explore their change rules in solubility and intestinal permeability of single-component and multi-components, and to determine the biopharmaceutical classification of extract of Huanglian from holistic level. The typical shake-flask method and HPLC were used to detect the solubility of single ingredient of alkaloids from extract of huanglian. The quantitative research of alkaloids in intestinal absorption was measured in single-pass intestinal perfusion experiment while permeability coefficient of extract of huanglian was calculated by self-defined weight coefficient method. Copyright© by the Chinese Pharmaceutical Association.

New sensor technologies in quality evaluation of Chinese materia medica: 2010-2015.

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Miao, Xiaosu; Cui, Qingyu; Wu, Honghui; Qiao, Yanjiang; Zheng, Yanfei; Wu, Zhisheng

2017-03-01

New sensor technologies play an important role in quality evaluation of Chinese materia medica (CMM) and include near-infrared spectroscopy, chemical imaging, electronic nose and electronic tongue. This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015, with prospects and opportunities for future research.

[Inheritance on and innovation of traditional Chinese medicine (TCM) flavor theory and TCM flavor standardization principle flavor theory in Compendium of Materia Medica].

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Zhang, Wei; Zhang, Rui-xian; Li, Jian

2015-12-01

All previous literatures about Chinese herbal medicines show distinctive traditional Chinese medicine (TCM) flavors. Compendium of Materia Medica is an influential book in TCM history. The TCM flavor theory and flavor standardization principle in this book has important significance for modern TCM flavor standardization. Compendium of Materia Medica pays attention to the flavor theory, explain the relations between the flavor of medicine and its therapeutic effects by means of Neo-Confucianism of the Song and Ming Dynasties. However,the book has not reflected and further developed the systemic theory, which originated in the Jin and Yuan dynasty. In Compendium of Materia Medica , flavor are standardized just by tasting medicines, instead of deducing flavors. Therefore, medicine tasting should be adopted as the major method to standardize the flavor of medicine.

[Report quality evaluation of systematic review or Meta-analysis published in China Journal of Chinese Materia Medica].

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Zhang, Yan; Yu, Dan-Dan; Cui, De-Hua; Liao, Xing; Guo, Hua

2018-03-01

To evaluate the report quality of intervention-related systematic reviews or Meta-analysis published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia Medica webpages to collect intervention-related systematic reviews or Meta-analysis since the first issue of the magazine. A total of 40 systematic reviews or Meta-analysis reports were included, including one network Meta-analysis. According to the PRISMA statement published in 2009, the report quality of the systematic reviews or Meta-analysis was evaluated. According to the results, 3 had the low quality, 30 had the medium quality, and 7 had the high quality. The average score for all of items was 30 points (21-30.5 points for the medium quality). The 17 high-quality (31-40 points) report items were title, rationale, objectives, information sources, study selection, data collection process, data items, risk of bias in individual studies, summary measures, risk of bias across studies, study selection, study characteristics, risk of bias within studies, results of individual studies, synthesis of results, risk of bias across studies and funding; the 4 medium-quality (21-30.5 points) reporting items were eligibility criteria, search, limitations and conclusions; and the 6 low-quality (Materia Medica is medium, and it is necessary to improve the quality standard of the report. Copyright© by the Chinese Pharmaceutical Association.

META-ANALYSIS OF THE SCIENTIFIC CONTENTS OF MATERIA SOCIO-MEDICA JOURNAL IN THE PERIOD 2009-2015.

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Masic, Izet; Begic, Edin; Zunic, Lejla; Donev, Doncho

2016-02-01

Materia Socio Medica Journal has a long history. It was founded in 1978. To evaluate journal articles in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2009-2015. A total of 99 articles were published in Materia Socio Medica during 2015 and it shows an upward trend during the period 2009-2015. Original articles are present in majority during the last seven years (69,2%). Analyzing the last seven years, 44,1% of articles were from the field of clinical medicine. Articles from the fields of public health show an upward trend during the last four years. Collaboration rate in 2015 was 0,95. Authors of the articles are from ten countries (four continents). H index of journal is 8 and g index is 12 (Publish or Perish software). According to GoogleScholar, h5 index for Materia Socio Medica is 8 and h5 median is 9. The objectives of the journal in the next year are: to become a part of the Scopus and Web of Science databases, further internationalization and promotion of the journal in the country and the region, revision and broadening of the Editorial Board, trying to follow trend in reducing the number of days required for a decision on acceptance or revision of article and involvement of the younger generation of professionals and scientists into the journal work and publishing scope, which will lead to emergence of new enthusiasm and ideas (Journal intends to follow the trends of modern biomedical publishing worldwide).

Back to the roots: A quantitative survey of herbal drugs in Dioscorides' De Materia Medica (ex Matthioli, 1568).

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Staub, P O; Casu, L; Leonti, M

2016-09-15

De Materia Medica written by Pedanios Dioscorides (1 century CE) has shaped European and Mediterranean herbal medicine to a large extent. Despite its fundamental importance for modern medico-botanical traditions the content of this work has never been systematically assessed. We present a quantitative survey of the botanical drugs described in De Materia Medica (ex Matthioli, 1568) and identify overall therapeutic, diachronic and botanical patterns. The extracted data may serve as a baseline and help to better contextualize research on herbal drugs and phytotherapy. Therapeutic uses of herbal drugs were extracted through line-by-line reading of a digitized version of the treatise. For each plant usage mentioned in the text we recorded (I) the chapter number, (II) the putative botanical identity, (III) the plant part, (IV) the symptoms or disease, (V) the mode of administration, (VI) our biomedical interpretation of the ancient ailment or disease description as well as (VII) the organ- and symptom-defined category under which the use was filed. An introduction to Dioscorides' De Materia Medica and Matthioli's Renaissance commentary is followed by a description of the employed methodology. The results and discussion section introduces the generated database comprising 5314 unique therapeutic uses of 536 plant taxa and 924 herbal drugs. Separate subsections address salient patterns such as the frequent recommendation of Fabaceae seeds for dermatology, Apiaceae seeds as antidotes and Apiaceae exudates for neurology and psychosomatic disorders as well as the heavy reliance on subterranean parts as drugs. The therapeutic knowledge described in De Materia Medica (ex Matthioli, 1568) offers unique insights into classical Mediterranean epidemiology and herbal medicine. Drugs that lost importance over time as well as remedies used for diseases now controlled by preventive medicine and industrially produced drugs may be interesting starting points for research on herbal

The antiepileptic Materia Medica of Pediacus Dioscorides.

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Eadie, M J

2004-09-01

Since it was written about the middle of the 1st Century AD, and up to comparatively recent times, the great Herbal, or Materia Medica, of Dioscorides provided medicine with its chief source of information about what were then considered therapeutic substances. The work contained data on various materials of botanical, biological and mineral origin which were claimed to provide benefit to sufferers from epilepsy, though often with no clear underlying rationale for their use. Some of these materials continued to be used as antiepileptic remedies over many centuries till they were finally recognised to be without useful effect in the disorder. The longest survivor amongst the Dioscoridean antiepileptic remedies was a rather esoteric one, viz. two stones taken from the belly of a young swallow during the rising phase of the moon and also whilst the swallow's parent birds were absent from the nest. The stones, or one of them, were worn against the skin of the seizure sufferer. The use of the swallow stones for epilepsy was recommended as late as in the writings of Thomas Willis (1675).

META-ANALYSIS OF THE SCIENTIFIC CONTENTS OF MATERIA SOCIO-MEDICA JOURNAL IN THE PERIOD 2009–2015

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Masic, Izet; Begic, Edin; Zunic, Lejla; Donev, Doncho

2016-01-01

Introduction: Materia Socio Medica Journal has a long history. It was founded in 1978. Aim: To evaluate journal articles in 2015 and compare findings to previous years. Material and methods: The study has retrospective and descriptive character, and included the period 2009-2015. Results: A total of 99 articles were published in Materia Socio Medica during 2015 and it shows an upward trend during the period 2009-2015. Original articles are present in majority during the last seven years (69,2%). Analyzing the last seven years, 44,1% of articles were from the field of clinical medicine. Articles from the fields of public health show an upward trend during the last four years. Collaboration rate in 2015 was 0,95. Authors of the articles are from ten countries (four continents). H index of journal is 8 and g index is 12 (Publish or Perish software). According to GoogleScholar, h5 index for Materia Socio Medica is 8 and h5 median is 9. Conclusions: The objectives of the journal in the next year are: to become a part of the Scopus and Web of Science databases, further internationalization and promotion of the journal in the country and the region, revision and broadening of the Editorial Board, trying to follow trend in reducing the number of days required for a decision on acceptance or revision of article and involvement of the younger generation of professionals and scientists into the journal work and publishing scope, which will lead to emergence of new enthusiasm and ideas (Journal intends to follow the trends of modern biomedical publishing worldwide). PMID:27047258

[Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis].

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Yan, Dan; Xiao, Xiao-he

2011-05-01

Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods (including bio-potency and bio-activity fingerprint) were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the dao-di herbs and bioassay.

[Effect of multicomponent environment on intestinal permeability of puerarin in biopharmaceutics classification system of Chinese materia medica].

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Liu, Yang; Wang, Gang; Dong, Ling; Tang, Ming-Min; Zhu, Mei-Ling; Dong, Hong-Huant; Hou, Cheng-Bo

2014-12-01

The evaluation of permeability in biopharmaceutics classification system of Chinese materia medica (CMMBCS) requires multicomponent as a whole in order to conduct research, even in the study of a specific component, should also be put in the multicomponent environment. Based on this principle, the high content components in Gegen Qinlian decoction were used as multicomponent environmental impact factors in the experiment, and the relevant parameters of intestinal permeability about puerarin were measured with using in situ single-pass intestinal perfusion model, to investigate and evaluate the intestinal permeability of puerarin with other high content components. The experimental results showed that different proportions of baicalin, glycyrrhizic acid and berberine had certain influence on intestinal permeability of puerarin, and glycyrrhizic acid could significantly inhibit the intestinal absorption of puerarin, moreover, high concentration of berberine could promote the absorption of puerarin. The research results indicated that the important research ideas of permeability evaluation in biopharmaceutics classification system of Chinese materia medica with fully considering the effects of other ingredients in multicomponent environment.

[Applications and approved projectsof general program, young scientist fund and fund for less developedregion of national natural science funds in discipline of Chinese materia medica, NSFC in 2012].

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Huang, Ming-Qing; Han, Li-Wei; Wu, Xiu-Hong; Bi, Ming-Gang; Shang, Hong-Cai; Liu, Yun-Fang; He, Wei-Ming; Li, Dan-Dan; Dong, Yan; Wang, Chang-En

2013-01-01

The applications accepted and approved by general program, young scientist fund and fund for less developed region of national natural science funds in the discipline of Chinese materia medica, NSFC in 2012 have been introduced. The research contents of the funded projects in the popular research areas have been summarized and the problems in the applications have been analyzed to give a reference to the scientists in the field of Chinese materia medica.

[Classes of crude drugs and its distribution of producing area in the attached illustrations in Ben cao tu jing (Illustrated Classic of Materia Medica)].

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Xu, T; Peng, H S

2016-03-01

Ben cao tu jing (Illustrated Classic of Materia Medica) is the earliest extant atlas book of materia medica in China, with 933 attached drawings. Among them, the largest portion, amounting to 670, are herbaceous plants, mostly commonly used, with definite marks of the origin producing areas, distributed across 149 administrative divisions(prefectures and counties) of the Song Dynasty, most of them in Northern area which were distributed denser than those in Southern area. The densest ones were located in Southern Shanxi, Eastern Sichuan and Eastern Anhui. In the attached drawings, the frequency of highest occurrence appeared in this Classic are three prefectures, Chuzhou, Shizhou and Guangzhou.

[Textual research on Costus root (Aucklandia lappa Decne) in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica)].

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Li, Guangyan; Wang, Dequn; Fang, Shiying; Xu, Maohong

2014-05-01

Aucklandia lappa Decne was first recorded in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica). Through the textual research of herbal literature, it was found that the costus root in the Sheng nong ben cao jing perhaps was not the plant of Aucklandia lappa Decne of Compositae, but the eaglewood or Lignum Aquilasria Resinatum based on the comprehensive judgment of shape, taste, nature, and function etc. In the Sheng nong ben cao jing, it only includes costus root without the title of eaglewood, and Tao Hongjing recorded both herbs together in his Ming yi bie lu (Supplementary Records of Celebrated Physicians), which became a foreshadow of misunderstanding of the later generations. Beginning from the Tang ben cao (Materia Medica of the Tang Dynasty), the costus root was considered as the plant of Auckiandia lappa Decne from the Compostae with its profound influence until now.

[Design and implementation of data checking system for Chinese materia medica resources survey].

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Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jin, Yan; Jing, Zhi-Xian; Qi, Yuan-Hua; Wang, Ling; Zhao, Yu-Ping; Wang, Wei; Guo, Lan-Ping; Huang, Lu-Qi

2017-11-01

The Chinese material medica resources (CMMR) national survey information management system has collected a large amount of data. To help dealing with data recheck, reduce the work of inside, improve the recheck of survey data from provincial and county level, National Resource Center for Chinese Materia Medical has designed a data checking system for Chinese material medica resources survey based on J2EE technology, Java language, Oracle data base in accordance with the SOA framework. It includes single data check, check score, content manage, check the survey data census data with manual checking and automatic checking about census implementation plan, key research information, general survey information, cultivation of medicinal materials information, germplasm resources information the medicine information, market research information, traditional knowledge information, specimen information of this 9 aspects 20 class 175 indicators in two aspects of the quantity and quality. The established system assists in the completion of the data consistency and accuracy, pushes the county survey team timely to complete the data entry arrangement work, so as to improve the integrity, consistency and accuracy of the survey data, and ensure effective and available data, which lay a foundation for providing accurate data support for national survey of the Chinese material medica resources (CMMR) results summary, and displaying results and sharing. Copyright© by the Chinese Pharmaceutical Association.

Alshamel fi Sana'at Tebbi'at: A Comprehensive Book on the Materia Medica.

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Mosaffa-Jahromi, Maryam; Kiani, Hossein

2016-05-01

Ala-al-din abu Al-Hassan Ali ibn Abi-Hazm al-Qarshi al-Dimashqi, known as Ibn al-Nafis (1210-1288 AD), was a Muslim Syrian physician primarily famous for being the first to describe the pulmonary circulation of the blood. The most voluminous of his books is Alshamel fi Sana'at tebbi'at, which is a comprehensive medical encyclopedia. It comprised 300 volumes of notes, from which only 80 volumes are published. His writings are cataloged in many libraries around the world. The aim of this review article, as a tribute to Ibn al-Nafis, was to introduce his valuable but neglected encyclopedia of Materia Medica. Ibn al-Nafis' traditional approach in his "Alshamel fi Sana'at tebbi'at" book is studied in the present article. Alshamel fi Sana'at tebbi'at covers three branches of knowledge. The first category is devoted to theoretical traditional medicine. The second is in four sections where much of it is not available yet. The third category is on Materia Medica covering the aspect of Unani medicine, from which only 28 volumes of the comprehensive book on the traditional medicine have been found so far. The latter, introduces mono-ingredient medications in alphabetical order. Each chapter, in several parts, is dedicated to the botanical characteristics and nature of each mono-ingredient medication. In addition, this book explains traditional pharmacokinetic of every single medication for each human body organs. Based on pharmaco-mechanistic perspective on Alshamel fi Sana'at tebbi'at, it could be considered as the main reference book on traditional medicine and pharmacy, worthy of revival.

Herbal diuretics in medieval Persian and Arabic medicine.

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Shoja, Mohammadali M; Tubbs, R Shane; Bosmia, Anand N; Fakhree, Mohammad A A; Jouyban, Abolghasem; Balch, Margaret Wood; Loukas, Marios; Khodadoust, Kazem; Khalili, Majid; Eknoyan, Garabed

2015-06-01

In accord with the notions of humoralism that prevailed in medieval medicine, therapeutic interventions, including diuretics, were used to restore the disturbed balance among the four humors of the human body: blood, phlegm, yellow bile, and black bile. Most diuretics were derived from plants. The primary textual reference on herbal diuretics was Dioscorides's De Materia Medica, which was written during the first century CE. The authors reviewed the medieval medical texts written in Persian and Arabic and compiled a list of 135 herbal diuretics used by the medieval medical authorities for treating various ailments. Between the 8th and 11th centuries CE, Middle Eastern physicians systematically reviewed extant books on medicine and pharmacotherapy and compiled new and expanded lists of herbal medicines, diuretics in particular. Furthermore, they introduced new chemical methods of extraction, distillation, and compounding in the use of herbal medicines. Several herbal remedies now are considered as potentially safe and affordable alternatives to chemical pharmaceuticals. Thus, research on medieval herbal therapies may prove to be relevant to the practice of current cardiovascular and renal pharmacotherapy. The authors propose that modern research methods can be employed to determine which of these agents actually are effective as diuretics.

[Experience of treatment and understanding of impediment disease in Shen nong ben cao jing (Shen-ntonz's Classic of Materia Medica)].

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Ding, Hongchang; Wang, Zhenrui

2015-01-01

As a book with significant historical materials for the research of impediment disease not to be ignored, Shen nong ben cao jing (Shennong's Classic of Materia Medica) contains, among its 365 kinds of materia medica, 75 kinds of medicines related to impediment disease. Among the latter ones, 51 are related to "damp impediment", "cold-damp impediment", "wind-cold-damp impediment", "wind impediment", "wind-damp impediment", and "cold impediment"; 16 are related to "laryngeal impediment", "general impediment", and "blood impediment"; 8 are related to "muscular impediment", "stomach impediment", "hernia-conglomeration impediment", "internal consumptive-thirst impediment", "wilting impediment", and "hemiplegic impediment". To systematically analyze the properties, tastes, and effects of these medicines and its related knowledge, and then further explore the overall recognition and their treating experience of the physicians at that period would not only enrich the historical research on impediment disease, but also offer much help and reference to the understanding and treatment of impediment for contemporary clinicians.

Advance in quality assessment of Chinese materia medica using microscopic and morphological methods.

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Miao, Xiao-Su; Cui, Qing-Yu; Wang, Zhao-Yi; Liu, Xiao-Na; Zhao, An-Bang; Qiao, Yan-Jiang; Wu, Zhi-Sheng

2017-09-01

Quality evaluation plays a vital role in ensuring safety and effectiveness of Chinese materia medica (CMM). Microscopic and morphological technologies can be used to distinguish CMM's characteristics, such as shape, size, texture, section, and smell, for authenticity and quality control of CMM. The microscopic and morphological applications of novel micro-technology, colorimeter, and texture analyzer for CMM identification are summarized and the future prospect is discussed in this paper. Various styles and complex sources of CMM are systemically reviewed, including cormophyte medicinal materials, fruit and seeds, pollen grain, and spore materials. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

[Current situation of toxicity classification of Chinese materia medica and its research thoughts].

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Sun, Wenyan; Hou, Xiujuan; Wang, Bin; Zhu, Yuelan; Zhang, Shuofeng; Chang, Hongsheng; Sun, Jianning

2012-08-01

Toxicity of Chinese materia medica (CMM) is an important part of Chinese herbal nature theory. In clinical application, the dosage, time limitation and compatibility of CMM is mainly determined by toxicity. At present, there is no uniform toxicity classification standard for the evaluation of Chinese herbal toxicity. Therefore, it is significant to research toxicity classification of CMM. The current situation of toxicity classification of CMM is reviewed in this paper, and proposed research thoughts are as follows: the measurement of toxicity parameters, the confirmation of poisoning target organs, the investigation on toxic mechanism by serum pharmacology and toxicokinetics, the comprehensive evaluation on toxicity based on quantitative theory.

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica.

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Pu, Wei-Ling; Sun, Li-Kang; Gao, Xiu-Mei; Rüegg, Curzio; Cuendet, Muriel; Hottiger, Micheal O; Zhou, Kun; Miao, Lin; Zhang, Yun-Sha; Gebauer, Margaret

2017-10-01

Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica (CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine (CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment (TME). Here we briefly summarize the pivotal effects of TAMs in shaping the TME and promoting tumorigenesis, invasion, metastasis and immunosuppression. Furthermore, we illustrate the effects and mechanisms of CMM targeting TAMs in antitumor therapy. Finally, we reveal the CMM's dual-regulatory and multi-targeting functions on regulating TAMs, and hopefully, provide the theoretical basis for CMM clinical practice related to cancer therapy.

[New materia medica project: synthetic biology based bioactive metabolites research in medicinal plant].

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Wang, Yong

2017-03-25

In the last decade, synthetic biology research has been gradually transited from monocellular parts or devices toward more complex multicellular systems. The emerging plant synthetic biology is regarded as the "next chapter" of synthetic biology. The complex and diverse plant metabolism as the entry point, plant synthetic biology research not only helps us understand how real life is working, but also facilitates us to learn how to design and construct more complex artificial life. Bioactive compounds innovation and large-scale production are expected to be breakthrough with the redesigned plant metabolism as well. In this review, we discuss the research progress in plant synthetic biology and propose the new materia medica project to lift the level of traditional Chinese herbal medicine research.

PAT: From Western solid dosage forms to Chinese materia medica preparations using NIR-CI.

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Zhou, Luwei; Xu, Manfei; Wu, Zhisheng; Shi, Xinyuan; Qiao, Yanjiang

2016-01-01

Near-infrared chemical imaging (NIR-CI) is an emerging technology that combines traditional near-infrared spectroscopy with chemical imaging. Therefore, NIR-CI can extract spectral information from pharmaceutical products and simultaneously visualize the spatial distribution of chemical components. The rapid and non-destructive features of NIR-CI make it an attractive process analytical technology (PAT) for identifying and monitoring critical control parameters during the pharmaceutical manufacturing process. This review mainly focuses on the pharmaceutical applications of NIR-CI in each unit operation during the manufacturing processes, from the Western solid dosage forms to the Chinese materia medica preparations. Finally, future applications of chemical imaging in the pharmaceutical industry are discussed. Copyright © 2015 John Wiley & Sons, Ltd.

[Analysis of projects funded by NSFC in field of processing Chinese materia medica in recent five years].

Science.gov (United States)

Chen, Lei; Xia, Xing; He, Bo-sai; Hah, Li-wei

2015-05-01

The general situation of the approved and concluded projects of National Natural Science Foundation of China in the field of processing Chinese Materia Medica in recent five years has been reviewed. The progresses and achievements of some projects have been summarized in accordance with research area such as the processing principle, the processing technology, quality evaluation, toxicity and safety evaluation, etc. The researchers and project support units of the funded projects have been analyzed, and the problems of the applications have been also summarized.

Les gloses botaniques andalouses sur le manuscrit de Paris de la traduction arabe de la Materia Medica de Dioscorides

Directory of Open Access Journals (Sweden)

Ben Mrad, Ibrahim

2009-12-01

Full Text Available The following study focusses on a precious manuscript from the National Library in Paris, namely n.º 2849 of the Arabic manuscript collection. This is a manuscript of Andalusian origin of the Arabic translation of Materia Medica by Dioscorides, written in Syria at the beginning of the 13th century. Its margins are filled with glosses of synonymic nature, relating to the Greek terms of the plants described by the Greek pharmacologist and physician. These glosses, of Andalusian origin, offer a great terminological richness which is part of a large Arabic — mainly Andalusian — movement of revision and commentary of Materia Medica in Arabic. In the first part a general introduction to the manuscript is provided showing its significant value for a critical edition of the book, the glosses contained and, especially, of the Andalusian botanical glosses, insisting on their synonymic value and their terminological contribution. In a second part, a critical annotated edition of 44 glosses from the first maqāla of the book is proposed.

Se aborda en este trabajo el estudio de un precioso manuscrito de la Biblioteca Nacional de París, el n.º 2849 de los fondos árabes. Se trata de un manuscrito de origen andalusí que contiene la traducción al árabe de la Materia Medica de Dioscórides, escrito en Siria a principios del siglo XIII, cuyos márgenes están repletos de glosas de naturaleza sinonímica, relativas a los nombres griegos que reciben las plantas descritas por la farmacología griega. Estas glosas son de orígen andalusí, y ofrecen una gran riqueza terminológica que se inscribe en un amplio movimiento árabe, y más concretamente andalusí, de revisión y comentario de la traducción árabe de la Materia Medica. En la primera parte de este estudio se ofrece una presentación general del manuscrito, mostrando su valor para una reedición crítica de la obra, de las glosas que contiene y

The classification and application of toxic Chinese materia medica.

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Liu, Xinmin; Wang, Qiong; Song, Guangqing; Zhang, Guangping; Ye, Zuguang; Williamson, Elizabeth M

2014-03-01

Many important drugs in the Chinese materia medica (CMM) are known to be toxic, and it has long been recognized in classical Chinese medical theory that toxicity can arise directly from the components of a single CMM or may be induced by an interaction between combined CMM. Traditional Chinese Medicine presents a unique set of pharmaceutical theories that include particular methods for processing, combining and decocting, and these techniques contribute to reducing toxicity as well as enhancing efficacy. The current classification of toxic CMM drugs, traditional methods for processing toxic CMM and the prohibited use of certain combinations, is based on traditional experience and ancient texts and monographs, but accumulating evidence increasingly supports their use to eliminate or reduce toxicity. Modern methods are now being used to evaluate the safety of CMM; however, a new system for describing the toxicity of Chinese herbal medicines may need to be established to take into account those herbs whose toxicity is delayed or otherwise hidden, and which have not been incorporated into the traditional classification. This review explains the existing classification and justifies it where appropriate, using experimental results often originally published in Chinese and previously not available outside China. Copyright © 2013 John Wiley & Sons, Ltd.

Chinese Marine Materia Medica Resources: Status and Potential.

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Fu, Xiu-Mei; Zhang, Meng-Qi; Shao, Chang-Lun; Li, Guo-Qiang; Bai, Hong; Dai, Gui-Lin; Chen, Qian-Wen; Kong, Wei; Fu, Xian-Jun; Wang, Chang-Yun

2016-03-03

Chinese marine materia medica (CMMM) is a vital part of traditional Chinese medicine (TCM). Compared with terrestrial TCM, CMMM, derived from specific marine habitats, possesses peculiar chemical components with unique structures reflecting as potent pharmacological activities, distinct drug properties and functions. Nowadays, CMMM appears to be especially effective in treating such difficult diseases as cancers, diabetes, cardio-cerebrovascular diseases, immunodeficiency diseases and senile dementia, and therefore has become an important medicinal resource for the research and development of new drugs. In recent years, such development has attracted wide attention in the field of medicine. In this study, the CMMM resources in China were systematically investigated and evaluated. It was found that the historic experiences of Chinese people using CMMM have continuously accumulated over a period of more than 3600 years, and that the achievements of the research on modern CMMM are especially outstanding. By June 2015, 725 kinds of CMMMs from Chinese coastal sea areas have been identified and recorded, covering 1552 organisms and minerals. More than 3100 traditional prescriptions containing CMMMs have been imparted and inherited. However, the number of CMMMs is less than the 8188 terrestrial TCMs, from more than 12,100 medicinal terrestrial plants, animals and minerals. In the future, the research and development of CMMM should focus on the channel entries (TCM drug properties), compatibility, effective ingredients, acting mechanisms, drug metabolism and quality standard. This study reveals the high potential of CMMM development.

[Real-time detection of quality of Chinese materia medica: strategy of NIR model evaluation].

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Wu, Zhi-sheng; Shi, Xin-yuan; Xu, Bing; Dai, Xing-xing; Qiao, Yan-jiang

2015-07-01

The definition of critical quality attributes of Chinese materia medica ( CMM) was put forward based on the top-level design concept. Nowadays, coupled with the development of rapid analytical science, rapid assessment of critical quality attributes of CMM was firstly carried out, which was the secondary discipline branch of CMM. Taking near infrared (NIR) spectroscopy as an example, which is a rapid analytical technology in pharmaceutical process over the past decade, systematic review is the chemometric parameters in NIR model evaluation. According to the characteristics of complexity of CMM and trace components analysis, a multi-source information fusion strategy of NIR model was developed for assessment of critical quality attributes of CMM. The strategy has provided guideline for NIR reliable analysis in critical quality attributes of CMM.

[Applications and spproved projects of general program, young scientist fund and fund for less developed region of national natural science funds in discipline of Chinese materia medica, NSFC in 2011].

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Han, Liwei; Wang, Yueyun; He, Wenbin; Zhang, Junjie; Bi, Minggang; Shang, Hongcai; Shang, Deyang; Wang, Chang'en

2012-03-01

The applications accepted and approved by general program, young scientist fund and fund for less developed region of national natural science funds in the discipline of Chinese materia medica, NSFC in 2011 have been introduced. The character and problems in these applications have been analyzed to give a reference to the scientists in the field of Chinese material medica.

Effects of Chinese Materia Medica-Fubao Danggui Jiao on experimental endometriosis.

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Sun, Xing; Chen, Lijue; Zeng, Fanbo

2011-01-01

The objective of this paper was to investigate the effects of a Chinese Materia Medica variant -Fubao Danggui Jiao (FDJ)-on experimental endometriosis. An endometriosis model was created by virtue of auto-transplantation of endometrial tissue onto rats' abdominal walls. The implants were allowed to grow for 30 days until the successful completion of the model. After that, forty endometriotic rats were randomly divided into four study groups and given different treatments: (1) negative control group (water, 2ml/kg, per os); (2) FDJ-A group (FDJ, 2ml/kg, per os); (3) FDJ-B group (FDJ, 4ml/kg, per os); (4) Danazol group (70mg/kg, per os). After 30 days with treatments, the volumes of endometriotic implants in each rat were measured. The implants and normal uterine horns were removed for routine histological examination. FDJ caused significant decreases in volumes of the surviving endometriotic implants, with two different doses having statistically equivalent effects. Upon histological examination, FDJ was observed to cause regression of epithelium and stroma of endometriotic implants. FDJ had revealed promising therapeutic effects on endometriosis.

[Academic heritage of Jiu huang ben cao (Materia Medica for Relief of Famines) in Japan].

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He, Huiling; Xiao, Yongzhi

2014-11-01

Jiu huang ben cao (Materia Medica for Relief of Famines) was the first monograph on famines herbal in the history of China, which creates a new research field of edible plants. Around the middle and late 17th century, Jiu huang ben cao was spread to Japan and aroused great attention of famous Japanese herbalists. Thus, all versions of different edition systems were circulated in Japan. Later, some famous Japanese scholar ssuccessively quoted texts of Jiu huang ben cao from the Nong zheng quan shu (Whole book on Agricultural Administration) spread in Japan, and block-printed it as an independent work. As a result, Jiu huang ben cao virtually circulated widely in Japan.

[Formulation of technical specification for national survey of Chinese materia medica resources].

Science.gov (United States)

Guo, Lan-Ping; Lu, Jian-Wei; Zhang, Xiao-Bo; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

2013-04-01

According to the process of the technical specification (TS) design for the fourth national survey of the Chinese materia medica resources (CMMR), we analyzed the assignment and objectives of the national survey and pointed out that the differences about CMMR management around China, the distribution of CMMR and their habitat, the economic and technological level, and even enthusiasm and initiative of the staff, etc. are the most difficult points for TS design. And we adopt the principle of combination of the mandatory and flexibility in TS design. We fixed the key points which would affect the quality of national survey first, then proposed the framework of TS which including 3 parts of organization and 11 parts of technique itself. The framework will serve and lead the TS preparation, which will not only provide an action standard to the national survey but will also have a profound influence to the popularization and application of the survey technology of CMMR. [Key words

[Study and comparison on HPLC fingerprints of flavonoids of frequently used Chinese materia medica in citrus].

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Chen, Yonggang; Lin, Li

2011-10-01

To establish the HPLC fingerprint of flavonoids of the six clinical frequently used Chinese materia medica for regulating Qi flow,such as Citri grandis, C. grands, Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride, Aurantii Fructus, and Aurantii Fructus Immaturus from Citrus, and analysis differences in the fingerprints to provide scientific basis for profile-effect research and clinical reasonable use. HPLC was performed on a C18 column with methanol-water (with acetic acid), to establish HPLC fingerprints of the six kinds of medicinal herbs on the same chromatograph condition. The six frequently used Chinese materia medica were divided into naringin type and hesperidin type according to the method of phytochemotaxonomy. Based on the retention time of chromatograph peaks, C. grandis and C. grands had fifteen common peaks; Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride, Aurantii Fructus and Aurantii Fructus Immaturus had ten common peaks. All herbs had five common peaks. Compared with mutual model, the holistic similarity of chromatograms of C. grandis and C. grands was in the range of 0.9285 - 0.9962. The degree of similarity was high. For Citri Reticulatae Pericarpium, Citri Reticulatae Pericarpium Viride and Aurantii Fructus Immaturus, it was in the range of 0.9221 - 0.9973 and high. But the similarity of Aurantii Fructus was only in 0.4547 - 0.7733 with the mutual model. The established fingerprints of flavonoids of the six common traditional Chinese medicines can be used to compare the differences intuitively. Meanwhile, the peak height and peak areas of characteristic peaks are different remarkably, but whether it is connected with the different function of regulating Qi flow of the six medical materials in clinical use, is still needed to be studied.

[Impacts of multicomponent environment on solubility of puerarin in biopharmaceutics classification system of Chinese materia medica].

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Hou, Cheng-Bo; Wang, Guo-Peng; Zhang, Qiang; Yang, Wen-Ning; Lv, Bei-Ran; Wei, Li; Dong, Ling

2014-12-01

To illustrate the solubility involved in biopharmaceutics classification system of Chinese materia medica (CMMBCS) , the influences of artificial multicomponent environment on solubility were investigated in this study. Mathematical model was built to describe the variation trend of their influence on the solubility of puerarin. Carried out with progressive levels, single component environment: baicalin, berberine and glycyrrhizic acid; double-component environment: baicalin and glycyrrhizic acid, baicalin and berberine and glycyrrhizic acid and berberine; and treble-component environment: baicalin, berberin, glycyrrhizic acid were used to describe the variation tendency of their influences on the solubility of puerarin, respectively. And then, the mathematical regression equation model was established to characterize the solubility of puerarin under multicomponent environment.

[Design and implementation of mobile terminal data acquisition for Chinese materia medica resources survey].

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Qi, Yuan-Hua; Wang, Hui; Zhang, Xiao-Bo; Jin, Yan; Ge, Xiao-Guang; Jing, Zhi-Xian; Wang, Ling; Zhao, Yu-Ping; Guo, Lan-Ping; Huang, Lu-Qi

2017-11-01

In this paper, a data acquisition system based on mobile terminal combining GPS, offset correction, automatic speech recognition and database networking technology was designed implemented with the function of locating the latitude and elevation information fast, taking conveniently various types of Chinese herbal plant photos, photos, samples habitat photos and so on. The mobile system realizes automatic association with Chinese medicine source information, through the voice recognition function it records the information of plant characteristics and environmental characteristics, and record relevant plant specimen information. The data processing platform based on Chinese medicine resources survey data reporting client can effectively assists in indoor data processing, derives the mobile terminal data to computer terminal. The established data acquisition system provides strong technical support for the fourth national survey of the Chinese materia medica resources (CMMR). Copyright© by the Chinese Pharmaceutical Association.

Authentication of Chinese Materia Medica decoction dregs. Part II: comparison before and after decoction of four Chinese Materia Medica that mainly comprise storage tissue.

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Wong, Lailai; Liang, Zhitao; Chen, Hubiao; Zhao, Zhongzhen

2012-02-01

Authentication of Chinese Materia Medica (CMM) decoction dregs is important for ensuring the efficacy and safety of CMM when they are used in decoction. If someone got worse or poisoned after taking a decoction while the formula is appropriate, the authentication of CMM dregs is the effective method to explore the reasons. Therefore, a systematic study on the authentication of CMM dregs was carried out. In this study, two pairs of easily confused CMM dregs, Fenge (Puerariae Thomsonii Radix) and Shanyao (Dioscoreae Rhizoma), Dihuang (Rehmanniae Radix) and Huangjing (Polygonati Rhizoma), which mostly comprise storage tissues, were investigated by comparing the morphological and microscopic characteristics. Fenge and Shanyao contain abundant starch granules. After decoction their dregs were hard, nonstarchy and horn-like. Fully gelatinized starch granules were found in the powder of Fenge dregs while incompletely gelatinized starch granules were occasionally found in the Shanyao dregs. In contrast, Dihuang and Huangjing contain water-soluble sugars. After decoction, their dregs were hard and brittle. Their parenchymatous cells were shrunken and unknown crystals were found under microscope. Hence, the morphological and microscopic characteristics of CMM before and after decoction were different, and different changes in the CMM dregs can be illustrated by the different nature of their ergastic substance. These differences could be used to authenticate CMM dregs. Copyright © 2011 Wiley Periodicals, Inc.

Chinese vegetative materia medica in a venereological treatise by Jean Astruc from 1740.

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Drobnik, Jacek

2016-07-01

Historical medical sources can be still queried for forgotten cures and remedies. Traditional Chinese medicine has dealt with lues venerea (syphilis) since the Five Dynasties period (10th century). Chinese indigenous materia medica and remedies recorded, studied or imported by the Europeans can reveal known or quite unknown medicinal plants. The studied Jean Astruc's work is a published ethnopharmacological survey carried out in Beijing in the 1730s and it deserves a modern interpretation. This is the first proposal to identify historical Chinese medicinal plants listed in a scarcely known medical treatise De Morbis venereis… ('On venereal diseases…') by Jean Astruc from 1740. I searched for the current uses and position of the taxonomically identified herbal stock in both traditional Chinese and official medical knowledge, with special attention to syphilis. Chinese names of drugs and their botanical identities (originally expressed by means of pre-Linnaean polynomials, and now interpreted as accepted binomials) were independently cross-checked with younger till most recent taxonomical and ethnopharmacological sources. Plants and drugs identified this way were queried for their modern applications in traditional Chinese and official medicine with special attention to sexually transmitted diseases (STD) and other uses which are similar to the 18th-century understanding of venereology. For 24 items of medicinal stock, 34 medicinal plants have been identified or suspected: Acacia catechu, Achyranthes bidentata, Akebia quinata, Angelica dahurica, A. sinensis, Aquilaria sinensis, Aralia cordata, Aristolochia fangchi, Chaenomeles sinensis, Ch. speciosa, Clematis vitalba, Coix lacryma-jobi, Commiphora myrrha, Cydonia oblonga, Daemonorops draco, D. jenkinsiana, Dictamnus dasycarpus, Dryobalanops sumatrensis, Forsythia suspensa, Glycyrrhiza uralensis, Lonicera confusa, L. hypoglauca, L. japonica, Ligusticum striatum (=L. chuanxiong), Piper kadsura, Pterocarpus

[Key content and formulation of national Chinese materia medica resources survey at county level].

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Lu, Jian-Wei; Zhang, Xiao-Bo; Li, Hai-Tao; Guo, Lan-Ping; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

2013-08-01

According to National Census for Water, National Population Census, National Land and Resources Survey, and work experience of experimental measures for national Chinese materia medica resources(CMMR) survey,the national CMMR survey at the county level is the key point of whole survey, that includes organization and management, field survey, sorting data three key links. Organization and management works of national CMMR survey needs to finish four key contents, there are definite goals and tasks, practicable crew, preparation directory, and security assurance. Field survey works of the national CMMR survey needs to finish five key contents, there are preparation works for field survey, the choice of the key survey area (samples), fill in the questionnaire, video data collection, specimen and other physical collection. Sorting data works of the national CMMR survey needs to finish tree key contents, there are data, specimen and census results.

[Study on processing adjuvant medicines in Lei Gong's treatise on preparation and broiling of materia medica (Leigong Paozhi Lun)].

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Zhang, Wei; Zhang, Ruixian

2010-09-01

There were 268 kinds of medicines recorded in the book of Lei Gong's Treatise on preparation and broiling of materia medica (Leigong Paozhi Lun). Among these medicines, 178 medicines were prepared with adjuvant medicines, including general and special compatible adjuvant medicines. These adjuvant medicines used in this book can be explained by the theory of "seven-relation compatibility". The author tried to explain the usage and their compatibility of these adjuvant medicines and put forward that attention should be paid to the changes in functions of medicines and the influences of society should be paid attention.

[The Seongho () School's Study of the Ancient Learning () and Its Influence on the Debate about Materia Medica in the Late Joseon Dynasty].

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Cho, Sung-San

2015-08-01

This study will determine the ways in which the ancient learning (gu xue, ) scholarship of the Seongho School, and its interest in the materia medica (ben cao xue, ) were related during the late Joseon period. The Seongho School centered its studies mainly on classical Chinese texts of the Han (206 BC－AD 220) and pre-Han (?－221 BC) (xian-qin lianghan, ) periods rather than those of the Tang and Song dynasties (618-1279). gu xue scholarship emerged during the Ming dynasty era (1368 －1644) as an alternative to the scholarly trends of the Song dynasty, which were dependent on Zhu Xi's (, 1130－1200) Neo-Confucianism and its interpretation of Han and pre-Han classical Chinese texts. This scholarly trend influenced Korean and Japanese literature, philosophy, and even medicine from the seventeenth through the nineteenth centuries. Focusing on Korean scholarship, we find a great deal of research regarding the influence of gu xue on Korean classical Chinese literature and Confucian philosophy in the late Joseon period; however, no study has examined how this style of scholarship influenced the field of medicine during the same period. This study will investigate how the intellectuals of the Seongho School, who did the most to develop gu xue among Joseon intellectuals, were influenced by this style of scholarship in their study of the materia medica. Jeong Yak-yong (1762－1836), the representative intellectual of the Seongho School, did not focus on complicated metaphysical medical theories, such as the Yin-Yang and Five Elements theory (yin yang wu xing shui, ) or the Five Movements and Six Atmospheres theory (wu yun liu qi shui, ). Instead, his interests lay in the exact diagnoses of diseases and meticulous herbal prescriptions which formed an essential part of the Treatise on Exogenous Febrile Disease (Shang han lun, ) written by Zhang Zhungjing (, 150－219) in the Han dynasty. The Treatise was compatible with the scholarly purpose of gu xue in that they both

[Study on supply and demand relation based on two stages division of market of Chinese materia medica].

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Yang, Guang; Guo, Lan-Ping; Wang, Nuo; Zeng, Yan; Huang, Lu-Qi

2014-01-01

The complex production processes and long industrial chain in traditional Chinese medicine (TCM) market result in difficulty in Chinese market microstructure research. Based on the defining the logical relationships among different concepts. This paper divides TCM market into two stages as Chinese materia medica resource market and traditional Chinese Patent Medicines market. Under this foundation, we investigated the supply capacity, approaching rules and motivation system of suppliers in TCM market, analyzed the demand situation in the perspective of demand side, and evaluated the purchasing power in terms of population profile, income, and insurance. Furthermore we also analyzed the price formation mechanism in two stages of TCM market. We hope this study can make a positive and promotion effect on TCM market related research.

[The significance of drawing on experience of experimental study on Chinese materia medica during the Republican period].

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Li, Nan; Wan, Fang

2015-05-01

During the period of the Republic of China, researches of experiments on Chinese materia medica developed extensively with the scientific process of Chinese medicine. Although the technology standard was relatively low and the reference value, limited. The experiences, positive or negative, obtained at that time still has reference significance to today's Chinese medicine scientific research. The notion that traditional Chinese medical and scientific research be conducted under the guidance of TCM theory; valuable experience contained in the ancient literature of traditional Chinese medicine be collected; and the transformation capacity of scientific research be elevated, has been accepted by modern TCM professionals. If you go back to the history, it can be seen that this notion was summarized through repeated practice during the critical moment of traditional Chinese medicine, which should be emphasized and its understanding deepened at any time.

Chinese materia medica used in medicinal diets.

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Tan, Fang; Chen, Yalin; Tan, Xiaolei; Ma, Yunyun; Peng, Yong

2017-07-12

Medicinal diets have a history of more than 2000 years. Locally referred to as yaoshan (Chinese: ), a medicinal diet is understood in China as a dietary product that combines herbs and food with the purpose of preventing and treating diseases or improving health under the guidance of traditional Chinese medicine theory. Medicinal diets are used in Chinese people's daily life and in specialized restaurants. Hundreds of Chinese materia medica (CMM) are used in medicinal diets; however, a comprehensive evaluation of medicinal diets is lacking. This is an exploratory study that aims to identify the CMM that are most frequently used in medicinal diets and to provide an updated view of the current situation of medicinal diets in China. A field study of 1221 people in 32 Chinese provinces was conducted over a period of approximately 6 months and included various types of interviews as well as a written questionnaire. Two approaches were used to analyse the data collected in the survey: (1) estimating the frequency of CMM consumed in daily diets; and (2) collecting CMM used in medicinal diet restaurants. Complementary information on the selected CMM was obtained from relevant databases, including PubMed, Google Scholar, Baidu Scholar, CNKI, and Web of Science. Ten CMM were reported as commonly used by more than 50% of the participants. Among these 10 species, most medicinally used parts were seeds and fruits. Pharmacological data from the literature revealed that these species are associated with a wide spectrum of biological properties, including antitumour (80%), antioxidant (50%), anti-diabetic (40%), antilipemic (40%), anti-aging (40%), antimicrobial (40%) and cardioprotective (40%) activities. Our survey shows that most medicinal diet restaurants are located in the eastern part of China, with the greatest numbers being found in Beijing and Guangzhou. Only Dioscoreae Rhizoma, Lycii Fructus, Chrysanthemi Flos and Longan Arillus were frequently consumed both in daily

[Understanding and development strategy of health food containing Chinese materia medica].

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Wang, Lin-Yuan; Zhang, Jian-Jun; Wang, Chun; Wang, Jing-Xia; Zhu, Ying-Li; Wang, Jia; Gao, Xue-Min

2016-11-01

Health food containing Chinese materia medica (CMM) conforms to the development demands of the age of big health and the theory of preventive treatment. In the view of health care and improvement of resisting diseases, it plays an important role in the market. It is very necessary to have further study and discussion on health food containing CMM. First of all, by comparing, analyzing and summarizing, the health food containing CMM could be defined as the health food which is qualified in security and functionality evaluation, with the traditional Chinese medicines(TCM) within TCM standards as the main raw materials, and the formulation-composition is based on the theory of TCM. It is characterized by higher safety than medicines, stronger biological activities than common food, multiple forms, abundant raw materials and integrated supervision and management. Secondly, we discussed the research and development (R&D) strategies and rules of health food containing CMM, pointing out that the core tasks of R&D include the investigation of formula, technology and the standards of quality. The fundamental principles of declaration and production include scientificity, rationality, reality and uniformity. Three key requirements (security, functionality and controllability) in the review as well as the process management of R&D and the key-points of risks control were summarized in this paper. Finally, the dynamic trends of policies and regulations related to health food containing CMM were analyzed in the view of registration, recording, raw materials and functions, and then related suggestions were proposed. Therefore, this article will be helpful in overall understanding the health food containing CMM and play a guiding role for its research and development. Copyright© by the Chinese Pharmaceutical Association.

Chinese Marine Materia Medica. By Huashi Guan and Shuguang Wang. Shanghai Scientific and Technical Publishers, China Ocean Press, and Chemical Industry Press: Shanghai, Beijing, China, 2009; Hardback, 7064 pp; ¥ 2920; ISBN 978-7-5323-9958-1/R•2707; ISBN 978-7-5323-9973-4/R•2708; ISBN 978-7-1220-6012-9

Directory of Open Access Journals (Sweden)

Peter Proksch

2014-01-01

Full Text Available China is one of the first countries to use marine materia medica for treating diseases. Ancient books on Chinese herbology, such as Shennong Bencaojing (Shennong’s Classic of Materia Medica, Xinxiu Bencao (Newly Revised Materia Medica and Bencao Gangmu (Compendium of Materia Medica, have detailed more than 110 marine herbs and thousands of marine herbal formulas (including those for Chinese food therapy. A great deal of information on marine herbs and their applications in medicine, collected over thousands of years, has provided an important foundation for modern research in the area of marine drugs. Thanks to these records and references, the research and development of modern Chinese marine drugs continue to evolve and mature. Since the middle of the 20th century, special attention has been paid to traditional Chinese medicine, resulting in a significant increase in the number of newly discovered marine herbs. Comprehensive surveys in the past have also created a wealth of data on the pharmacology, chemistry, biology and ecology of marine medicinal bioresources. After thousands of years of research, historical references to traditional marine herbs are scattered throughout ancient books, local chronicles, medical books, or monographs on medicinal herbs. Unfortunately, there is no systematic way to collate or scientifically verify these references. Furthermore, during the last century, scientists around the world have accumulated large quantities of information on marine natural products, but these are also scattered throughout academic books and journals.

[Rapid assessment of critical quality attributes of Chinese materia medica (II): strategy of NIR assignment].

Science.gov (United States)

Pei, Yan-Ling; Wu, Zhi-Sheng; Shi, Xin-Yuan; Zhou, Lu-Wei; Qiao, Yan-Jiang

2014-09-01

The present paper firstly reviewed the research progress and main methods of NIR spectral assignment coupled with our research results. Principal component analysis was focused on characteristic signal extraction to reflect spectral differences. Partial least squares method was concerned with variable selection to discover characteristic absorption band. Two-dimensional correlation spectroscopy was mainly adopted for spectral assignment. Autocorrelation peaks were obtained from spectral changes, which were disturbed by external factors, such as concentration, temperature and pressure. Density functional theory was used to calculate energy from substance structure to establish the relationship between molecular energy and spectra change. Based on the above reviewed method, taking a NIR spectral assignment of chlorogenic acid as example, a reliable spectral assignment for critical quality attributes of Chinese materia medica (CMM) was established using deuterium technology and spectral variable selection. The result demonstrated the assignment consistency according to spectral features of different concentrations of chlorogenic acid and variable selection region of online NIR model in extract process. Although spectral assignment was initial using an active pharmaceutical ingredient, it is meaningful to look forward to the futurity of the complex components in CMM. Therefore, it provided methodology for NIR spectral assignment of critical quality attributes in CMM.

[Preliminary textual research on Zhijintang Sanctum re-revised version of Jinling edition of Ben cao gang mu (Compendium of Materia Medica)].

Science.gov (United States)

Zheng, Jinsheng

2014-03-01

The Zhijintang Sanctum version of the re-revised edition of Jinling edition of Ben cao gang mu (Compendium of Materia Medica)collected by Zhao Huiyuan of Baihe, Henan Province in 2008 was opted as one of the third batch of the National Directory of Rare Ancient Worksin 2010. On the second cover page (patent page), it is recorded as"Original Jiangxi version". However, it is investigated to find that most of its paper sheets were reprinted after the original Jinling version, only scores of paper sheets were supplemented block-printed, including the additional block-printed second preface and Li Jianyuan's submitted report of the Jiangxi version, the re-revised time of which should be after the Jiangxi edition, or 1603. The exact time can be determined only by checking it carefully against another Jinling re-revised version (the Sheyuantang Sanctum edition).

Psychiatry and psychology in medieval Persia.

Science.gov (United States)

Vakili, Nasser; Gorji, Ali

2006-12-01

The history of psychological sciences and especially the ways in which related disorders were treated in medieval Persia are not well known in the West. The main objective of this article is to review the clinical approaches to psychological disorders used by practitioners in medieval Persia. Several documents still exist from which the clinical data on different psychological syndromes in medieval Persia can be ascertained. Data for this review were identified by searches of MEDLINE, Current Contents, the Internet, references from relevant articles and books, the Astan-e-Ghods Razavi Library, the Tehran University Library, the Mashhad University Library, and the files of the authors. Search terms included psychiatry, psychology, Persian, medieval, Avicenna, and pharmacotherapy. The medieval practitioners defined various signs and symptoms, apparent causes, and hygienic and dietary rules for prevention of these disorders. Medieval Persian medical writings encouraged the treatment of psychological disorders by tackling the conditions that cause or contribute to the disorder and through the use of electrical-shock therapy, phlebotomy, psychotherapy, music and color therapy, and especially prescription of long lists of medicaments. Some of the approaches of doctors in medieval Persia are accepted today, although most remain largely unexamined. With further research, more of these treatments may be shown to be of use to modern medicine.

[Applications and prospects of on-line near infrared spectroscopy technology in manufacturing of Chinese materia medica].

Science.gov (United States)

Li, Yang; Wu, Zhi-Sheng; Pan, Xiao-Ning; Shi, Xin-Yuan; Guo, Ming-Ye; Xu, Bing; Qiao, Yan-Jiang

2014-10-01

The quality of Chinese materia medica (CMM) is affected by every process in CMM manufacturing. According to multi-unit complex features in the production of CMM, on-line near infrared spectroscopy (NIR) is used as an evaluating technology with its rapid, non-destructive and non-pollution etc. advantages. With the research in institutions, the on-line NIR applied in process analysis and control of CMM was described systematically, and the on-line NIR platform building was used as an example to clarify the feasibility of on-line NIR technology in CMM manufacturing process. Then, from the point of application by pharmaceutical companies, the current on-line NIR research on CMM and its production in pharmaceutical companies was relatively comprehensively summarized. Meanwhile, the types of CMM productions were classified in accordance with two formulations (liquid and solid dosage formulations). The different production processes (extraction, concentration and alcohol precipitation, etc. ) were used as liquid formulation diacritical points; the different types (tablets, capsules and plasters, etc.) were used as solid dosage formulation diacritical points, and the reliability of on-line NIR used in the whole process in CMM production was proved in according to the summary of literatures in recent 10 years, which could support the modernization of CMM production.

An improved association-mining research for exploring Chinese herbal property theory: based on data of the Shennong's Classic of Materia Medica.

Science.gov (United States)

Jin, Rui; Lin, Zhi-jian; Xue, Chun-miao; Zhang, Bing

2013-09-01

Knowledge Discovery in Databases is gaining attention and raising new hopes for traditional Chinese medicine (TCM) researchers. It is a useful tool in understanding and deciphering TCM theories. Aiming for a better understanding of Chinese herbal property theory (CHPT), this paper performed an improved association rule learning to analyze semistructured text in the book entitled Shennong's Classic of Materia Medica. The text was firstly annotated and transformed to well-structured multidimensional data. Subsequently, an Apriori algorithm was employed for producing association rules after the sensitivity analysis of parameters. From the confirmed 120 resulting rules that described the intrinsic relationships between herbal property (qi, flavor and their combinations) and herbal efficacy, two novel fundamental principles underlying CHPT were acquired and further elucidated: (1) the many-to-one mapping of herbal efficacy to herbal property; (2) the nonrandom overlap between the related efficacy of qi and flavor. This work provided an innovative knowledge about CHPT, which would be helpful for its modern research.

What has been overlooked on study of Chinese materia medica in the West?

Science.gov (United States)

Liu, Willow J H

2015-07-01

Chinese materia medica (CMM), including Chinese herbal, animal, and mineral medicine, has been widely researched in the past century for their biological and pharmacological activities. However, their mechanism and clinical efficacy studies did not always give expected results. For example, the most commonly used Chinese herb for menstrual disorders, Radix Angelicae sinensis, showed neither estrogenic nor progesteronic activity in laboratory and clinical studies. Its efficacy should not be denied simply based on such results, because it is mostly used together with other herbs in formulae. Moreover, its regulation on menstruation may take effect through other mechanisms, such as regulation of blood circulation. The key difference of Chinese medicine (CM) from conventional medicine is its unique holistic view on human body and diseases. CMM is mostly applied in clinic in the form of formulae. Study on individual CMM, simply using methods for development of conventional drugs, is unable to thoroughly reveal the power of CMM formulae. The reason may partly result from improper design due to the lack understanding about application principle of CMMs in CM, and/or to current lack of knowledge about the causes of some symptoms and diseases. This paper will introduce the importance of qi and blood in CM etiology and pathology, Zheng differentiation, formulation of CMMs, and explain why one formula can treat different diseases and one disease can be treated with different formulae. Examples in the paper will demonstrate that proper studies on Zheng and its corresponding clinically proven formulae could help scientists find new direction to explain and treat symptoms and diseases that so far modern medicine has been unable to, provided that the designer properly understands CM theories, etiology and pathology of CM, as well as modern medicine. Strategy suggestions about research methods for CMM and its formulae will be given at the end.

Discourse on pulse in medieval Persia--the Hidayat of Al-Akhawayni (?-983 A D.).

Science.gov (United States)

Khodadoust, Kazem; Ardalan, Mohammadreza; Ghabili, Kamyar; Golzari, Samad E J; Eknoyan, Garabed

2013-06-20

In a period of compilation, original observations and expansion (900-1100 A.D.), Persians described new clinical manifestations of the diseases and expanded the earlier knowledge of materia medica. In the epoch of the Arabic language domination in the scientific literature of this period, advent of medical authors to write in Farsi shined in the Persian principalities. Akhawayani Bokhari was by far the most outstanding scholar of the time who wrote one of the earliest pandects of medicine of the period, the Hidayat al-Mutallimin fi al-Tibb (Learner's Guide to Medicine) in new Persian. The Hidayat is a relatively short and simplified digest of medicine at the time providing a glimpse of high level of medical education at the Samanid period (819-999). The present article is a translation of the sections of the Hidayat related to the pulse and its characters and conditions affecting the pulse in an attempt to increase our knowledge of the medicine, and particularly the pulse examination throughout the medieval era. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

[Methodological quality and reporting quality evaluation of randomized controlled trials published in China Journal of Chinese Materia Medica].

Science.gov (United States)

Yu, Dan-Dan; Xie, Yan-Ming; Liao, Xing; Zhi, Ying-Jie; Jiang, Jun-Jie; Chen, Wei

2018-02-01

To evaluate the methodological quality and reporting quality of randomized controlled trials(RCTs) published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia webpage to collect RCTs since the establishment of the magazine. The Cochrane risk of bias assessment tool was used to evaluate the methodological quality of RCTs. The CONSORT 2010 list was adopted as reporting quality evaluating tool. Finally, 184 RCTs were included and evaluated methodologically, of which 97 RCTs were evaluated with reporting quality. For the methodological evaluating, 62 trials(33.70%) reported the random sequence generation; 9(4.89%) trials reported the allocation concealment; 25(13.59%) trials adopted the method of blinding; 30(16.30%) trials reported the number of patients withdrawing, dropping out and those lost to follow-up;2 trials （1.09%） reported trial registration and none of the trial reported the trial protocol; only 8(4.35%) trials reported the sample size estimation in details. For reporting quality appraising, 3 reporting items of 25 items were evaluated with high-quality,including: abstract, participants qualified criteria, and statistical methods; 4 reporting items with medium-quality, including purpose, intervention, random sequence method, and data collection of sites and locations; 9 items with low-quality reporting items including title, backgrounds, random sequence types, allocation concealment, blindness, recruitment of subjects, baseline data, harms, and funding;the rest of items were of extremely low quality(the compliance rate of reporting item<10%). On the whole, the methodological and reporting quality of RCTs published in the magazine are generally low. Further improvement in both methodological and reporting quality for RCTs of traditional Chinese medicine are warranted. It is recommended that the international standards and procedures for RCT design should be strictly followed to conduct high-quality trials

Distinguishing the Chinese materia medica Tiepishihu from similar Dendrobium species of the same genus using histological and microscopic method.

Science.gov (United States)

Yu, Kun-Zi; Yan, Hua; Tai, Hai-Chuan; Zhang, Nan-Ping; Cheng, Xian-Long; Guo, Zeng-Xi; Ma, Shuang-Cheng; Wei, Feng

2017-07-01

The Chinese Materia Medica, Tiepishihu, used as a tonic for over one thousand years, is a well-known precious medicine in China. According to the Chinese Pharmacopoeia, its source is the species Dendrobium officinale Kimura et Migo, which is distinguished from other species in Dendrobium genus. However, these species from the same genus are similar with Tiepishihu and caused confusion in the market. To find a quick and simple method to distinguish Tiepishihu from other similar species, histologic and microscopic methods were combined together to investigate the transverse section of stem of Tiepishihu and other similar species. Phloroglucinol test solution with hydrochloric acid was used to reveal the lignified tissue by staining the transverse section of Tiepishihu and similar species. Results revealed the unique identification characteristics to distinguish Tiepishihu from similar species, which were difficult to distinguish by other methods. The identification characteristics of Tiepishihu include the cells of vascular bundle sheath were stained red, parenchyma cells were not stained red. What's more, other species can be distinguished from each other with microscopic and histological characteristics. These characteristics proved stable and can be easily observed by normal light microscopic examination. This method is rapid, accurate, stable, and inexpensive. © 2017 Wiley Periodicals, Inc.

The Doctrine of Signatures, Materia Medica of Orchids, and the Contributions of Doctor - Orchidologists.

Science.gov (United States)

Pearn, John

2012-12-01

The heritage of medicine is written in many forms. One repository is to be found in the history of orchids, the world's largest family of flowering plants. Orchids were so named by Theophrastus (c.372-288 BC) who recorded their medicinal use as an aphrodisiac and the promoter of virility, in the context of the Doctrine of Signatures. Such use endured for millennia, and was recorded both by Paracelsus (1493-1551) and Linnaeus (1707-1778). The history of orchidology and medicine are entwined in four domains: (a) orchids and their historical materia medica, within the paradigm of the Doctrine of Signatures; (b) the enduring and extensive contemporary medicinal and culinary use of orchids such as Vanilla and salep extracts of Orchis; (c) the scientific contributions of doctors as orchidologists; and (d) the heritage of more than a hundred doctors' names in the scientific etymology of the Orchidaceae family. Prominent orchidologists have included the Scottish doctor-soldier and botanist, Robert Brown (1773-1858); the Director of the State Herbarium at Leyden and the Rijks Museum, Carl Ludwig Blume (1796-1862); and Dr William Sterling MD (1888-1967). Among the more than 1250 genus names (and 33,000 species) of orchids are the names of more than a hundred doctors, their lives and works perpetuated in the scientific etymology of this family of exotic, beautiful, flamboyant, intriguing and often expensive flowers. Generic names record the lives and works of such as Aristotle (384-322BC) in Aristotelia Loureiro 1790; Cadet de Gassicourt (1769-1821) in Cadetia Gaudichaud 1826; Sir Joseph Dalton Hooker (1817-1911) in Sirhookera O. Kuntze 1891; and Dr Theodore Daniel Vrydag Zynen (fl. 1820-1850) in Vrydagzynea Blume 1858. One of the principal horticultural genera of orchids, Brassavola, records the life and work of the Ferrara and Padua physician and botanist, Antonio Musa Brassavola (1500-1555). The first Slipper Orchid bred as a hybrid, Paphiopedilum harrisianum (by John

Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage

Science.gov (United States)

Sun, Kai; Fan, Jingyu; Han, Jingyan

2015-01-01

Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are conditions with high mortality and serious long-term physical and cognitive disabilities. They have a major impact on global public health. These disorders are associated with multiple insults to the cerebral microcirculation, including reactive oxygen species (ROS) overproduction, leukocyte adhesion and infiltration, brain blood barrier (BBB) disruption, and capillary hypoperfusion, ultimately resulting in tissue edema, hemorrhage, brain injury and delayed neuron damage. Traditional Chinese medicine (TCM) has been used in China, Korea, Japan and other Asian countries for treatment of a wide range of diseases. In China, the usage of compound TCM preparation to treat cerebrovascular diseases dates back to the Han Dynasty. Even thousands of years earlier, the medical formulary recorded many classical prescriptions for treating cerebral I/R-related diseases. This review summarizes current information and underlying mechanisms regarding the ameliorating effects of compound TCM preparation, Chinese materia medica, and active components on I/R-induced cerebral microcirculatory disturbances, brain injury and neuron damage. PMID:26579420

Translation and Transliteration of Plant names in Ḥunayn b. Iḥsāq´s and Iṣṭifān b. Bāsil´s Arabic version of Dioscorides, De materia medica

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Touwaide, Alain

2009-12-01

Full Text Available This paper deals with the Arabic translation of De materia medica by the Greek author Dioscorides (1^st century A.D., particularly the rendering of plant names, which were sometimes properly translated and sometimes transliterated from the Greek. According to a traditional interpretation, the transliteration strategy was used by the translators when they did not know the exact Arabic equivalent of the plant names. I re-examine this interpretation here taking into account the role of plant names in the Greek text and the Andalusian works of botanical lexicography. As a result, I propose to interpret transliterations as a mean used by translators to keep visible the structure of the work, in which plant names played a certain role.

Este artículo se ocupa de la traducción árabe del texto griego del tratado De materia medica de Dioscórides (siglo I, especialmente de los fitónimos que, en unos casos, fueron traducidos al árabe y, en otros, transliterados del griego. Según la interpretación tradicional, la transliteración era una estrategia utilizada por los traductores cuando no conocían el equivalente exacto árabe de los nombres de las plantas. Se propone en este trabajo una revisión de esta interpretación, teniendo en cuenta el importante papel que los nombres de las plantas desempeñan en el texto griego, así como en las obras de los lexicógrafos y botánicos andalusíes, llegando a la conclusión de que las transliteraciones eran una técnica utilizada por los traductores para mantener visible la estructura general de la obra de Dioscórides, basada en gran parte en la nomenclatura de las plantas.

[Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

Science.gov (United States)

Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

2014-05-01

Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

UHPLC/Q-TOFMS-based metabolomics for the characterization of cold and hot properties of Chinese materia medica.

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Wang, Yang; Zhou, Shujun; Wang, Meng; Liu, Shuying; Hu, Yuanjia; He, Chengwei; Li, Peng; Wan, Jian-Bo

2016-02-17

The cold/hot property of Chinese materia medica (CMM) and the application of its corresponding knowledge in the diagnosis, differentiation and treatment of diseases have been considered to be the extremely important part of traditional Chinese medicine (TCM). As highly abstracted TCM theory, the cold/hot property of CMMs is still not fully understood and remains to be elucidated by systems biology approach. The cold and hot properties of CMM are mainly defined by the response of the body to a given CMM. Metabolomics is a promising systems biology method to profile entire endogenous metabolites and monitor their fluctuations related to an exogenous stimulus. Thus, a metabolomics approach was applied to characterize the cold and hot properties of CMMs. Mice were intragastrically administered three selected cold property CMMs (i.e., Rheum palmatum L., radix et rhizoma; Coptis chinensis Franch, rhizome and Scutellaria baicalensis Georgi, radix) and three hot property CMMs (i.e., Cinnamomum cassia (L.) J. Presl, cortex; Zingiber officinale Roscoe, rhizoma and Evodia rutaecarpa (Juss.) Benth., fructus) once daily for one week. The comprehensive metabolome changes in the plasma of mice after treatment with cold or hot property CMMs were characterized by ultra-high performance liquid chromatography/time of flight mass spectrometry (UHPLC/Q-TOF-MS), and the potential biomarkers related to cold and hot properties of CMM were explored. Metabolites perturbation in plasma occurs after treatment with cold CMMs and hot CMMs in mice, and 15 and 16 differential biomarkers were identified to be associated with the cold and hot properties of CMMs, respectively. Among them, LPC (18:0), LPC (18:1), LPC (20:4) and LPC (20:5) showed decreased trends in the cold property CMM treated groups, but increased in the hot property CMM treated groups. There is a strong connection between the cold/hot property of CMMs and lysophosphatidylcholines metabolism. This study offers new insight

Archaeology of Architecture and Archaeology of houses in Early Medieval Europe

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Quirós Castillo, Juan Antonio

2012-12-01

Full Text Available This paper aims to introduce the «Archaeology of Architecture and Household Archaeology in Early Medieval Europe» dossier, the object of which is to explore the different approaches, methodologies and themes analysed in the study of early medieval architecture in western Europe. More specifically, in what follows, analysis is undertaken of the contexts which explain the recent development of studies on this topic, as well as the main contributions of the seven papers which form this dossier. In addition, the main historical and archaeological problems raised by the analysis of this material record are also discussed.En este trabajo se presenta el dossier «Archaeology of Architecture and Household Archaeology in Early Medieval Europe», que pretende explorar los distintos enfoques, metodologías y temáticas analizadas en el estudio de las arquitecturas altomedievales en el marco de Europa occidental. Más concretamente se analizan los contextos que explican el desarrollo reciente de los estudios sobre esta materia, las principales aportaciones de los siete trabajos que conforman este dossier y se discuten los principales problemas históricos y arqueológicos que plantea el análisis de este registro material.

[Design and implementation of Chinese materia medica resources survey results display system].

Science.gov (United States)

Wang, Hui; Zhang, Xiao-Bo; Ge, Xiao-Guang; Jin, Yan; Wang, Ling; Zhao, Yan-Ping; Jing, Zhi-Xian; Guo, Lan-Ping; Huang, Lu-Qi

2017-11-01

From the beginning of the fourth national census of traditional Chinese medicine resources in 2011, a large amount of data have been collected and compiled, including wild medicinal plant resource data, cultivation of medicinal plant information, traditional knowledge, and specimen information. The traditional paper-based recording method is inconvenient for query and application. The B/S architecture, JavaWeb framework and SOA are used to design and develop the fourth national census results display platform. Through the data integration and sorting, the users are to provide with integrated data services and data query display solutions. The platform realizes the fine data classification, and has the simple data retrieval and the university statistical analysis function. The platform uses Echarts components, Geo Server, Open Layers and other technologies to provide a variety of data display forms such as charts, maps and other visualization forms, intuitive reflects the number, distribution and type of Chinese material medica resources. It meets the data mapping requirements of different levels of users, and provides support for management decision-making. Copyright© by the Chinese Pharmaceutical Association.

Authentication of Polygonati Odorati Rhizoma and other two Chinese Materia Medica of the Liliaceae family by pharmacognosy technique with GC-MS analysis.

Science.gov (United States)

Liu, Yingjiao; Liu, Canhuang; Yu, Yafei; Xu, Bei; Gong, Limin; Zeng, Xiaoyan; Xiao, Lan; Cheng, Qilai; Liu, Tasi

2015-02-01

Yuzhu (Polygonati Odorati Rhizoma), Kangdingyuzhu (Polygonati Prattii Rhizoma), and zhugenqiyuzhu (Disporopsis Fuscopictae Rhizoma) are of the same family, but of different genera. They have all often used in Chinese Materia Medica (CMM) as Polygonati Odorati Rhizoma in China market. Three species of CMM are confused. For better application, we need to identify these plants accurately. This study use pharmacognosy technique and GC-MS analysis, three species of CMM were authenticated. In macroscopic characteristics, the fruit of Polygonati Odorati Rhizoma is blue-black, while the other two are maroon and dark purple orderly. Nodes of Polygonati Odorati Rhizoma are upward and light uplift, about 1 cm spacing, while the other are not. As for microscopic characteristics, the cortex of Polygonati Odorati Rhizoma only occupies about 1/5 of the radius of the transverse section with inconspicuous endodermis, which is much smaller than others. The type of vascular bundles of Polygonati Odorati Rhizoma is closed collateral, but the other is amphivasal. Raphides of calcium oxalate are scattered, but Raphides of the other two are like brooms and neat rows. GC-MS analysis of essential oil could provide different characteristics to distinguish three species. Twenty-three compounds were identified from essential oil of Polygonati Odorati Rhizoma and the main components were n-hexadecanoic acid (49.45%), while n-hexadecanoic acid of the other two are 23.92% and 9.45%. The content of n-hexadecanoic is strongly different. This research was aimed to establish a method by pharmacognosy and GC-MS analysis to identify three CMM and for providing scientifical data to ensure accuracy of origin of three species. © 2014 Wiley Periodicals, Inc.

[Good agricultural practice (GAP) of Chinese materia medica (CMM) for ten years: achievements, problems and proposals].

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Guo, Lan-Ping; Zhang, Yan; Zhu, Shou-Dong; Wang, Gui-Hua; Wang, Xiu; Zhang, Xiao-Bo; Chen, Mei-Lan; He, Ya-Li; Han, Bang-Xing; Chen, Nai-Fu; Huang, Lu-Qi

2014-04-01

This paper aims to summarize the achievements during the implementation process of good agricultural practice (GAP) in Chinese Materia Medica (CMM), and on basis of analyzing the existing problems of GAP, to propose further implementation of GAP in TCM growing. Since the launch of GAP in CMM growing ten years ago, it has acquired great achievements, including: (1) The promulgation of a series of measures for the administration of the GAP approval in the CMM growing; (2) The expanded planting area of CMM; (3) The increased awareness of standardized CMM growing among farmers and enterprises; (4) The establishment of GAP implementation bases for CMM growing; (5) The improvement of theory and methodology for CMM growing; (6) The development of a large group of experts and scholars in GAP approval for CMM production. The problems existing in the production include: (1) A deep understanding of GAP and its certification is still needed; (2) The distribution of the certification base is not reasonable; (3) The geo-economics effect and the backward farming practices are thought to be the bottlenecks in the standardization of CMM growing and the scale production of CMM; (4) Low comparative effectiveness limits the development of the GAP; (5) The base of breeding improved variety is blank; (6) The immature of the cultivation technique lead to the risk of production process; (7) The degradation of soil microbial and the continuous cropping obstacle restrict the sustainable development of the GAP base. To further promote the health and orderly GAP in the CMM growing, the authors propose: (1) To change the mode of production; (2) To establish a sound standard system so as to ensure quality products for fair prices; (3) To fully consider the geo-economic culture and vigorously promote the definite cultivating of traditional Chinese medicinal materials; (4) To strengthen the transformation and generalization of basic researches and achievements, in order to provide technical

Scientometric Analysis of the Journals of the Academy of Medical Sciences in Bosnia and Herzegovina.

Science.gov (United States)

Masic, Izet; Begic, Edin; Zunic, Lejla

2016-02-01

Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health

Medieval Chinese syntax

OpenAIRE

Anderl, Christoph

2017-01-01

“Medieval Chinese Syntax” aims to provide a sketch of the development of function words and syntactic structures during the Chinese Medieval period, including Early Medieval Chinese (ca. 0-700 A.D.) and Late Medieval Chinese (ca. 700-1100).

Digital Materia

OpenAIRE

Lindgren, Marcus; Richey, Emma

2014-01-01

Med tankar från pedagogen Montessori och filosoferna Platon och Baudrillard har detta arbete behandlat frågor om datorn och dess betydelse för en grafiker. Frågeställningen formulerades efter hand och lydde tillslut: ”Hur kan materia te sig i digital form?” Forskningen resulterade i en hypotes för hur digital materia skulle födas i datorn: genom att blanda två uppsättningar av data, såsom två genuppsättningar tillsammans skapar en ny organism. Under produktionen utvecklades därmed en metod fö...

[Irrigants and intracanal medicaments in endodontics].

Science.gov (United States)

Zehnder, Matthias; Lehnert, Birgit; Schönenberger, Kathrin; Waltimo, Tuomas

2003-01-01

Modern, biologic root canal therapy should be performed with suitable irrigating solutions and intracanal medicaments. The goal of endodontic treatment is to free the treated tooth from infection and prevent reinfection as thoroughly as possible by means which do not put the organism at risk. In this review of the literature, an evidence-based concept for irrigation and medication of root canal systems is presented. Irrigants and medicaments are discussed with respect to their antimicrobial, tissue-dissolving and endotoxin-decontaminating capacity in relation to their systemic toxicity. Recent findings pertaining to interactions of root canal medicaments and irrigating solutions and their impact on a sound irrigating and medicating concept are discussed.

The "schola medica salernitana": the forerunner of the modern university medical schools.

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de Divitiis, Enrico; Cappabianca, Paolo; de Divitiis, Oreste

2004-10-01

The schola medica salernitana is considered the oldest medical school of modern civilization. Salerno's long medical tradition began during the Greco-Roman period in a Greek colony named Elea, where Parmenides decided to found a medical school. The fame of the school became more and more important during the 10th century, and it was best known in the 11th century. In the middle of 12th century, the school was at its apogee, and Salerno provided a notable contribution to the formulation of a medical curriculum for medieval universities. The most famous work of the Salernitan School was the Regimen Sanitatis Saleritanum, a Latin poem of rational, dietetic, and hygienic precepts, many of them still valid today. The school also produced a physician's reference book, with advice on how to treat a patient, a sort of code of conduct to help the physician to respect the patient and his or her relatives. The first science-based surgery appeared on the scene of the discredited medieval practice in Salerno, thanks to Roger of Salerno and his fellows. He wrote a book on surgery, called Rogerina or Post Mundi Fabricam, in which surgery from head to toe is described, with surprising originality. The important contribution to the School of Salerno made by women as female practitioners is outlined, and among them, Trotula de Ruggiero was the most renowned. The period when the School of Salerno, universally recognized as the forerunner of the modern universities, became a government academy was when Frederick II reigned over the Kingdom of the Two Sicilies, as Emperor of the Holy Roman Empire.

El cuerpo como materia educativa en la prosa castellana de los siglos 13 y 14 - The body as educational content in late medieval spanish prose: 13th and 14th centuries

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Miguel Vicente Pedraz, España

2012-07-01

, excerpted from late-medieval spanish texts.Key-words: education of princes, body, courtesy, Middle Ages, castilian medieval literature. EL CUERPO COMO MATERIA EDUCATIVA EN LA PROSA CASTELLANA  DE LOS SIGLOS 13 Y 14ResumenEl artículo propone la siguiente hipótesis: la génesis medieval de la educación física remite, sobre todo, a la emergencia de la sensibilidad cortés, concretada en la apariencia distinguida y en el autodominio gestual. Desde esta perspectiva, las destrezas corporales propias de la actividad bélica o de la práctica lúdica caballeresca constituyen un aspecto de menor relevancia; sólo una expresión de dicha sensibilidad en la que lo fundamental es que manifiesta el relativo declive de la idea de estirpe y de los atributos de la “sangre” como dispositivos determinantes de la excelencia, proceso que abriría paso a un creciente interés educativo por la instrucción del cuerpo, más allá de la ejercitación y del mero endurecimiento físico. De acuerdo con la teoría de Norbert Elias, expuesta en El proceso de la civilización, se muestran algunos ejemplos literarios de la pujanza de esta nueva sensibilidad en el entorno de las letras castellanas del Bajo Medioevo.Palabras-clave: educación de príncipes, cuerpo, cortesía, literatura medieval castellana.  LE CORPS COMME MATIERE EDUCATIF EN LA PROSE ESPAGNOLE DU 13E ET 14E SIECLESRésumé Cet article propose l'hypothèse suivante: la genèse médiévale de l'éducation physique remete, surtout, a l'émergence de la sensibilité courtoise, qui se manifeste dans les gestes aprence distingués et la maîtrise de soi. Dans cette perspective, les compétences de corps propre de l'activité militaire ou de la pratique constituant un aspect ludique  du gentilhomme d'importance mineure; une seule expression de cette sensibilité, puisque la clé est qui exprime le déclin relatif de la notion de souche et les attributs du sang en tant que déterminants dispositifs d'excellence, un processus qui

Medications and their use in the Graeco-Roman era

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François Retief

2007-09-01

Full Text Available As from the 6th century BC Graeco-Roman medical therapy comprised three components, viz. diet and healthy lifestyle (regimen, surgery and medicaments (pharmacotherapy, of which the latter was the oldest. Although the Corpus Hippocraticum (5th century BC, with minor Egyptian influence, contained no text of medicines as such, and seemed to prefer regimen to medicaments, it nevertheless laid the foundation for the empirical use of pharmacotherapy (free of superstition and magic for the next millennium. The first Greek herbal was produced by Diocles in the 4th century BC, when the botanist Theophrastus also wrote his classic works on plants which contained a significant contribution on herbal medicines. The Alexandrian Medical School systematized and expanded Hippocratic medicine, and Herophilus introduced compound preparations. The concept that medicaments cure illness by restoring the bodily balance of humours and primary properties was largely perpetuated, but new views on physiology were gradually emerging. Unfortunately the bulk of original contributions from Hellenistic doctors are lost to posterity and only known to us through the writings of for example Celsus and Galen in Roman times. The interesting history of theriac, the so-called universal antidote, is reviewed. In the 1st century Dioscorides produced his Materia Medica which remained an authoritative pharmacopoeia up to modern times. Galen’s empiric views on pharmacotherapy (2nd century, still largely based on Hippocrates, became dogma in Medieval times, but mysticism and superstition gradually swept back into medicine. Retrospectively it is clear that with the exception of certain analgesics and narcotics like opium, Graeco-Roman medicaments were pharmacologically inert (even toxic and obtained positive results largely through a placebo effect.

Medieval monsters, in theory and practice.

Science.gov (United States)

2014-01-01

The past two decades have witnessed a plethora of studies on the medieval monster. These studies have contributed significantly to our understanding of religion, art, literature, and science in the Middle Ages. However, a tendency to treat the medieval monster in purely symbolic and psychological terms ignores the lived experiences of impaired medieval people and their culture's attitudes toward them. With the aid of recent insights provided by disability studies, this article aims to confront "real" medieval monsters--e.g., physically impaired human beings--in both their human and monstrous aspects.

Kaempferol, a flavonoid compound from Gynura medica induced ...

African Journals Online (AJOL)

Background: Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica, kaempferol and its glycosides are the major constituents of G. medica. Here we ...

What Is Medieval European Literature?

OpenAIRE

Borsa, Paolo; Høgel, Christian; Mortensen, Lars Boje; Tyler, Elizabeth

2015-01-01

The editors of Interfaces: A Journal of Medieval European Literatures explain the scope and purpose of the new journal by mapping out the significance and possible meanings of the three key terms of the subtitle: ‘literature,’ ‘medieval,’ ‘Europe.’ The specific theme of Issue 1 is introduced: ‘Histories of Medieval European Literatures: New Patterns of Representation and Explanation.’ With respect to this theme, theoretical problems concerning teleology and the present possibilities for liter...

Ancient and medieval Iberia seen through glass: An archaeometric perspective; La Hispania antigua y medieval a través del vidrio: la aportación de la arqueometría

Energy Technology Data Exchange (ETDEWEB)

Juan Ares, J. de; Nadine Schibille, N.

2017-11-01

The study of ancient and medieval glasses has identified distinct compositional groups as a result of the chemical characteristics of the raw materials used for its production. Archaeometric analysis can determine the provenance of the glass, and has demonstrated a large-scale production and commercialisation of raw glass throughout the Mediterranean during the ancient and medieval periods. Secondary workshops on the Iberian Peninsula imported raw glass from the Near East for the better part of the first millennium CE, following a similar pattern observed elsewhere in the Mediterranean region. However, there are some indications that point to a local production of glass and that deserve further investigation. In the ninth century, natron glass was replaced in al-Ándalus by plant ash and lead-rich glass that may represent a local production. Little is known about the production or use of glass in the Christian parts of the peninsula during this period. The increasing volume of analytical data on Spanish glass demonstrates the potential of an archaeometric approach to shed light not only on the production and trade of glass on the Iberian Peninsula but also on the ancient and medieval economy more generally. [Spanish] El estudio del vidrio antiguo y medieval ha permitido identificar distintos grupos composicionales que son resultado de las características químicas de las materias primas empleadas en su fabricación. Los análisis arqueométricos permiten determinar la procedencia del vidrio, demostrando que el vidrio primario fue producido y comercializado a gran escala a través del Mediterráneo durante la Antigüedad y la Edad Media. Los talleres hispanos importaron vidrio primario desde Próximo Oriente durante la mayor parte del primer milenio d. C. siguiendo un patrón paralelo al resto del Mediterráneo. Sin embargo, algunos indicios señalan que pudieron convivir con vidrios de fabricación local que merecen ser investigados. En el siglo IX el vidrio de

Essays on medieval computational astronomy

CERN Document Server

Bergón, José Chabás

2014-01-01

In Essays on Medieval Computational Astronomy the authors provide examples of original and intelligent approaches and solutions given by medieval astronomers to the problems of their discipline, mostly presented in the form of astronomical tables.

Climate change. Climate in Medieval time.

Science.gov (United States)

Bradley, Raymond S; Hughes, Malcolm K; Diaz, Henry F

2003-10-17

Many papers have referred to a "Medieval Warm Period." But how well defined is climate in this period, and was it as warm as or warmer than it is today? In their Perspective, Bradley et al. review the evidence and conclude that although the High Medieval (1100 to 1200 A.D.) was warmer than subsequent centuries, it was not warmer than the late 20th century. Moreover, the warmest Medieval temperatures were not synchronous around the globe. Large changes in precipitation patterns are a particular characteristic of "High Medieval" time. The underlying mechanisms for such changes must be elucidated further to inform the ongoing debate on natural climate variability and anthropogenic climate change.

La Física de la Materia Desordenada

OpenAIRE

Cabrillo García, Carlos

2007-01-01

Presentado en el IV Curso de Iniciación a la Investigación en Estructura de la Materia: Desde las partículas subatómicas hasta los compuestos moleculares (Instituto de Estructura de la Materia, CSIC, 28-30 de Marzo de 2007).

Superficie Específica y Estado Vital de la Materia

OpenAIRE

J. Hernando Ordoñez

1992-01-01

Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piens...

Indice por Materias

Directory of Open Access Journals (Sweden)

Montoya H Luz Marina

1982-09-01

Full Text Available Un índice es una lista de palabras o frases indicadores asociados que permite la ubicación de material al interior de un libro o una publicación, en este caso será por el nombre de la materia.

Medievalism: From Ruskin toChesterton

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Marko Jenko

2009-12-01

Full Text Available This article deals with the topic of medievalism as all existing, still evolving, and future forms of reception of the Middle Ages, focusing primarily on the issues of the term itself and the problems that arise with its definition, its occurrence in John Ruskin’s time, various historical forms, and their variations, especially considering some of the implications of its official or academic aspect – namely, medieval studies in general. Consequently, the article shows that medievalism entails a step beyond or beneath the usual opposition between the real and false Middle Ages. In terms of objectivity as an ideal, as the search or quest for the real Middle Ages (and also as a reaction against subjective receptions, colored by presuppositions, preconceptions, and prejudice, medievalism shifts our perspective on the opposition between the objective and subjective, inaugurating a field of study that centers on the objective-subjective, which should not be seen or taken as a synthesis. Furthermore, it pinpoints a change or shift in the status of truth itself: a truth with no guarantee. Primarily making reference to art history, the article emphasizes the importance of medievalist fantasies and proposes a much needed re-reading of Panofsky’s take on the scholastic habitus. Both terms, fantasy and/or habitus, permeate the field of medievalism, opening what is perhaps the most important question: that of (works of art and materiality.

Why We Need a Medieval Narratology: A Manifesto

Directory of Open Access Journals (Sweden)

Eva von Contzen

2014-12-01

Full Text Available In the wake of the growing interest in diachronic approaches and the historicizing of narratology, a medieval narratology is called for which systematically scrutinizes medieval forms and functions of narration. In the first part of the article, the problems of applying classical narratological theories to medieval literature are sketched, as well as the reasons for the relative invisibility of the narratological studies already conducted by medievalists. In the second part, the main parameters of a medieval narratology are outlined by means of selected sample analyses across a range of genres. A medieval narratology, it is argued, requires necessary shifts and modifications of existing theories, but also an open dialogue between the disciplines. Both narratologists and medievalists can profit from such an endeavor, which does not reject classical and post-classical theories. Rather, it is based on an informed understanding of the historical grounding of narrative forms and their place in the history of literature. The essay rounds off with a proposal of “Ten Theses for a Medieval Narratology”.

The effect of endodontic regeneration medicaments on mechanical properties of radicular dentin

Science.gov (United States)

Yassen, Ghaeth H.

Endodontic regeneration treatment of necrotic immature teeth has gained popularity in recent years. The approach suggests a biological alternative to induce a continuous root development. In this project, three in vitro experiments were conducted to investigate the effect of three medicaments used in endodontic regeneration on mechanical properties and chemical structure of radicular dentin. In the first experiment, we investigated longitudinally the effect of medicaments on the indentation properties of the root canal surface of immature teeth using a novel BioDent reference point indenter. A significant difference in the majority of indentation parameters between all groups was found after one-week and one-month application of medicaments (p double antibiotic paste (DAP) > control > calcium hydroxide [Ca(OH)2]. The four-week exposure of dentin to TAP and DAP caused 43% and 31% increase in total indentation distance outcome, respectively. In the second experiment, we investigated longitudinally the effect of medicaments on the chemical structure of immature radicular dentin by measuring the phosphate/amide I ratios of dentin using Attenuated Total Reflection Fourier Transform Infrared Spectroscopy. Phosphate/amide I ratios were significantly different between the four groups after one week, two weeks and four week application of medicaments (p untreated dentin > DAP-treated dentin > TAP-treated dentin. In the third experiment, we investigated longitudinally the effect of medicaments on root fracture resistance and microhardness of radicular dentin. For the microhardness, the two-way interaction between group and time was significant (pmedicaments caused significant decrease in fracture resistance ranging between 19%-30% after three month application compared to one week application. The three medicaments used in endodontic regeneration caused significant change in the chemical integrity of the superficial radicular dentin and significantly affected the indentation

Inactivation of local root canal medicaments by dentine: an in vitro study.

Science.gov (United States)

Haapasalo, H K; Sirén, E K; Waltimo, T M; Ørstavik, D; Haapasalo, M P

2000-03-01

The aim of the study was to investigate the inactivation by dentine of the antibacterial activity of various commonly used local root canal medicaments. The medicaments tested were saturated calcium hydroxide solution, 1% sodium hypochlorite, 0.5% and 0.05% chlorhexidine acetate, and 2/4% and 0.2/0.4% iodine potassium iodide. Dentine was sterilized by autoclaving and crushed into powder with a particle size of 0.2-20 microns. Aliquots of dentine suspension were incubated with the medicaments in sealed test tubes at 37 degrees C for 24 h or 1 h before adding the bacteria. In some experiments bacteria were added simultaneously with dentine powder and the medicament. Enterococcus faecalis A197A was used as a test organism. Samples for bacterial culturing were taken from the suspensions at 5 min, 1 h and 24 h after adding the bacteria. Dentine powder had an inhibitory effect on all medicaments tested. The effect was dependent on the concentration of the medicament as well as on the length of the time the medicament was preincubated with dentine powder before adding the bacteria. The effect of calcium hydroxide on E. faecalis was totally abolished by the presence of dentine powder. Similarly, 0.2/0.4% iodine potassium iodide lost its effect after preincubation for 1 h with dentine before adding the bacteria. The effect of 0.05% chlorhexidine and 1% sodium hypochlorite on E. faecalis was reduced but not totally eliminated by the presence of dentine. No inhibition could be measured when full strength solutions of chlorhexidine and iodine potassium iodide were used in killing E. faecalis. The dentine powder model appears to be an efficient tool for the study of interactions between local endodontic medicaments, dentine, and microbes.

Analysing Medieval Urban Space; a methodology

Directory of Open Access Journals (Sweden)

Marlous L. Craane MA

2007-08-01

Full Text Available This article has been written in reaction to recent developments in medieval history and archaeology, to study not only the buildings in a town but also the spaces that hold them together. It discusses a more objective and interdisciplinary approach for analysing urban morphology and use of space. It proposes a 'new' methodology by combining town plan analysis and space syntax. This methodology was trialled on the city of Utrecht in the Netherlands. By comparing the results of this 'new' methodology with the results of previous, more conventional, research, this article shows that space syntax can be applied successfully to medieval urban contexts. It does this by demonstrating a strong correlation between medieval economic spaces and the most integrated spaces, just as is found in the study of modern urban environments. It thus provides a strong basis for the use of this technique in future research of medieval urban environments.

Medieval Romances: "Perceval" to "Monty Python."

Science.gov (United States)

Jehle, Dorothy M.

A selection of romances from medieval literature can be used successfully in undergraduate literature classes to trace the appearance and relevance of medieval themes, motifs, and characters in works of modern poetry, fiction, and film. New scholarly editions, historiographies, translations, and modernizations give both teachers and students more…

Compatibility of drug property in effective components of Chinese materia medica%试论组分中药的药性配伍

Institute of Scientific and Technical Information of China (English)

陶丽; 陆茵; 王爱云; 陈文星

2012-01-01

中药有效组分配伍是当前开展中药现代化研究的重要模式,通过传统饮片活性组分分离及二次配伍以实现功效最大化.尽管有效组分配伍并不脱离原方的整体效应,但功效物质标准化即组分中药研究存在组分拆分简单而药性拆分困难的问题,因此需要明确组分样品库中各组分与其所属中药的性味离合关系.决定中药宏观药性的物质基础是其包含的微观化学成分,而基于化学信息学和知识发现的药性判别方法存在各自的局限性,真实客观的药性表征体系仍应回归到动态、可持续性定量反映药物与机体的相互作用结果的生物效应模型中去,在此基础上可以选择药少力专、基于药性组合的代表药对继而开展配伍组分的药性配伍规律研究,这对合理设计配伍组分及提高其有效性和安全性具有重大意义.%Effective components combination of Chinese materia medica (CMM) is an important model for study on the modernization of CMM. The maximum effectiveness could be obtained through the separation and secondary combination of the effective components in traditional processed pieces. Although the effective components combination does not break away from the overall effect of the original prescriptions, the effective components normalization, i.e. research on the effective components of CMM, faces the problems that is easy to decompose the components but hard to decompose the drug natures. Therefore, it needs to well define the relationship between the separation and reunion of each component and its CMM in sample library. The material basis for the CMM macroscopic drug natures is precisely their microscopic chemical ingredient. However, there are some respective limitations to recognize the drug natures by chemoinformatics and knowledge discovery, a real and objective characterization system for the evaluation on the natures of CMM and their components should return to the

[Neurology in medieval regimina sanitatis].

Science.gov (United States)

de Frutos González, V; Guerrero Peral, A L

2011-09-01

In medical medieval literature some works about dietetics stand out. Dietetics, as a separate branch of medicine, includes not only food or drinks, but other environmental factors influencing on health. They are known as regimina sanitatis or salutis, and specially developed in the Christian west. They generally consisted of a balance between the Galenic "six non-natural things"; factors regulating health and its protection: environment, exercise, food, sleep, bowel movements and emotions. After reviewing the sources and defining the different stages of this genre, we have considered three of the most out-standing medieval regimina, the anonymous Regimen sanitatis salernitanum, Arnaldo de Vilanova's Regimen sanitatis ad regem aragonum and Bernardo de Gordon's Tractatus of conservatione vite humane. In them we review references to neurological disease. Though not independently considered, there is a significant presence of neurological diseases in the regimina. Dietetics measures are proposed to preserve memory, nerves, or hearing, as well as for the treatment of migraine, epilepsy, stroke or dizziness. Regimina are quiet representative among medical medieval literature, and they show medieval physicians vision of neurological diseases. Dietetics was considered useful to preserve health, and therapeutics was based on natural remedies. 2010 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

The rise of traditional Chinese medicine and its materia medica: a comparison of the frequency and safety of materials and species used in Europe and China.

Science.gov (United States)

Williamson, Elizabeth M; Lorenc, Ava; Booker, Anthony; Robinson, Nicola

2013-09-16

Due to the global rise in the use of traditional Chinese medicine (TCM), Chinese materia medica (medicinal materials, or CMM) are giving cause for concern over their evidence base, safety/possible toxicity, questionable quality and use of endangered species of both animals and plants. However, little if anything is actually known about the range of species used to produce CMM used in Europe and even in China. This study represents the first attempt to identify and compare the most important CMM used in both regions, to begin the process of assessing the risks to public health and possible future benefits. Data were collected from a convenience sample of TCM practitioners in the EU and mainland China, using a paper/online survey. Among other questions, respondents were asked (1) which conditions they most commonly treated using CMM and the likelihood of them using herbal manufactured products and decoctions in addition to raw herbs; (2) the perceived frequency with which they observed adverse events to CMM; (3) the frequency and reasons for use of 1 herbal formula and 6 specific individual herbs; (4) an open question about other CMM they used, including materials of non-plant origin. Data were entered into PASW statistics package and analysed using frequency tables, cross-tabulations and chi-squared tests to compare EU and Chinese results. From a total of 747 useable questionnaires (420 from China, 327 from the EU) of those responding from the EU, TCM was generally more commonly used for obstetric/gynaecological and dermatological conditions, compared to neurological and gastrointestinal diseases in China. Disorders treated by Chinese practitioners were more varied, and often more serious, than those treated by their European counterparts, and the range of materials used in China was wider. The potential for toxicity was not high in either region, but although greater in China due to the use of more potent CMM, the incidence of side effects was perceived to be

JEWISH SUFISM IN MEDIEVAL ISLAM

OpenAIRE

Epafras, Leonard C.

2011-01-01

This article is a literary research and preliminary examination to a unique interaction between Jews and Sufism that taken place in medieval Islamic ruling. In the face of the present antagonistic posture of Jews and Muslims relationship that dominates the public sphere, in history, there are some examples of interaction of the two people beyond confictual narrative. One of them is Jewish mysticism that adopted Sufism into their spiritual ideal, which took place in the medieval era. We might ...

Wind Diagrams in Medieval Iceland

DEFF Research Database (Denmark)

Kedwards, Dale

2014-01-01

This article presents a study of the sole wind diagram that survives from medieval Iceland, preserved in the encyclopaedic miscellany in Copenhagen's Arnamagnæan Institute with the shelf mark AM 732b 4to (c. 1300-25). It examines the wind diagram and its accompanying text, an excerpt on the winds...... from Isidore of Seville's Etymologies. It also examines the perimeter of winds on two medieval Icelandic world maps, and the visual traditions from which they draw....

Veterinary pharmacology: history, current status and future prospects.

Science.gov (United States)

Lees, P; Fink-Gremmels, J; Toutain, P L

2013-04-01

Veterinary therapeutics, based on the art of Materia Medica, has been practised for countless centuries, but the science of veterinary pharmacology is of very recent origin. This review traces the contribution of Materia Medica to veterinary therapeutics from the Egyptian period through to the Age of Enlightenment. The first tentative steps in the development of the science of veterinary pharmacology were taken in the 18th century, but it was not until the mid 20th century that the science replaced the art of Materia Medica. This review traces the 20th century developments in veterinary pharmacology, with emphasis on the explosion of knowledge in the 35 year period to 2010. The range of factors which have influenced the current status of the discipline are reviewed. Future developments are considered from the perspectives of what might be regarded as desirable and those innovations that might be anticipated. We end with words of encouragement for young colleagues intent upon pursuing a career in veterinary pharmacology. © 2013 Blackwell Publishing Ltd.

Superficie Específica y Estado Vital de la Materia

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J. Hernando Ordoñez

1992-03-01

Full Text Available

Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piensa es el fenómeno más grandioso de la creación.

Sin entrar en disquisiciones sobre la naturaleza, manifestaciones y formas de la energía, me permito hacer unas a manera de divagaciones sobre los diferentes estados de la materia, que es una forma de la energía.

Estados de la materia

Sabemos que la mínima porción de la materia es el átomo, que tiene una composición compleja, que no es del caso estudiar. Los átomos pueden existir aislados y estar en lo que llamamos estado iónico. Si los átomos se juntan, forman moléculas, y su existencia constituye el estado molecular. Si las moléculas se juntan, forman complejos más grandes y tendremos las micelas, que constituyen el estado coloidal.

Hasta aquí nuestros conocimientos nos son familiares, triviales. Pero hay un estado más complejo, en el cual entra materia en estado iónico, molecular y coloidal entrelazados entre sí, con propiedades totalmente diferentes. La materia en este estado adquiere caracteres extraordinarios tales como el de crecer, reproducirse, independizarse de las leyes físicas, puede autorregular su composición química, autorregular sus manifestaciones físicas, reaccionar ante los estímulos más variados, puede llegar hasta alturas inconcebibles integrando ideas. A este estado fue al que llamé en publicación anterior (1 estado vital, concepto que fue corroborado más ‘tarde por J.R. Brown (2 cuando me coment

The virtues of balm in late medieval literature.

Science.gov (United States)

Truitt, Elly R

2009-01-01

This article argues that balm, or balsam, was, by the late medieval period, believed to be a panacea, capable of healing wounds and illnesses, and also preventing putrefaction. Natural history and pharmacological texts on balm from the ancient and late antique periods emphasized specific qualities of balm, especially its heat; these were condensed and repeated in medieval encyclopedias. The rarity and cost of balsam, from antiquity through the medieval period, and the high rate of counterfeiting also demonstrate its high demand and significance in medicine and religious ritual. Travel writing and itineraria from the early and central medieval periods added a new layer to ideas about the capabilities of balsam: that it originated from a Christian miracle and was a particularly Christian plant.

Dramatic Aspects of Medieval Magic in Scandinavia

DEFF Research Database (Denmark)

Søndergaard, Leif

2011-01-01

The arcle deal with the performative aspects of medieval spells and rituals. The most important spells are cited in extenso and commented uopn.......The arcle deal with the performative aspects of medieval spells and rituals. The most important spells are cited in extenso and commented uopn....

Materia strana romanzo scientifico

CERN Document Server

Gómez Cadenas, Juan José

2012-01-01

Nel Laboratorio europeo per la fisica delle particelle, il CERN di Ginevra, sta per vedere la luce uno dei più grandi progressi scientifici di tutti i tempi: la scoperta di un nuovo stato della materia, il cosiddetto "plasma di quark". La direttrice del CERN, Helena Le Guin, teme però che insieme al plasma si stiano formando grumi letali di materia strana, in grado di scatenare una reazione a catena che potrebbe distruggere l'intero pianeta. Mentre Helena cerca disperatamente di far fronte alla crisi, a Ginevra arrivano Irene de Ávila, una giovane e promettente fisica teorica, e il maggiore Héctor Espinosa, un militare americano assegnato alla sede dell'ONU per lavorare a un progetto ultrasegreto legato alla non proliferazione delle armi nucleari: inizia così un'appassionante vicenda in cui convergono rivalità scientifiche, peripezie personali e rischiose operazioni di spionaggio che porteranno i protagonisti fino in Iran.

Reuse of worn-out medicaments with adsorbent properties for the removal of manganese

International Nuclear Information System (INIS)

Millan C, E.

2005-01-01

The current investigations on the treatment of worn-out medicaments in Mexico, reveal that most of these treatments are carried out with the purpose to reduce the packing and diminish the toxic level that presents each one of those medicaments. That it reach to reuse of them is their packing material and/or their cover. Once treated, the worn-out medicaments move to a sanitary filler. With relationship to the investigation works that have been carried out for the manganese removal in solution, they show a great number of materials that they are used for this end, as well as the parameters that influence in the process, such as the concentration of the element, the solution type in that is content and the pH. However, it is not mentioned in none of them the reuse of the worn-out medicaments (Talcid and Melox), as adsorbent materials for the removal of metals from the water. To carry out the present investigation they were selected therefore, to the one Talcid and the Melox because its present adsorbent properties, with the purpose to remove the manganese like water pollutant. Once that the worn-out medicaments were obtained, they put on in contact with different organic solvents, to obtain the active principle, due to the pharmaceutical presentation of the two medicaments that was obtained was in suspension. The active principles of the two medicaments were characterized by means of high vacuum scanning electron microscopy (SEM), elementary microanalysis (EDS) and X-ray diffraction (XRD). The experimental part consisted in putting in contact manganese solutions with the active principles of the worn-out medicaments, varying the time of contact and the concentration. The manganese quantification in the liquid phase carried out by means of atomic absorption spectroscopy (AAS). It was found that the kinetic model that better describes the sorption process of manganese in both worn-out medicaments (Talcid and Melox) it is that of pseudo second order. Those results of

[Development of rapid setting-drying device for herbarium specimens and its application in survey of Chinese materia medica resources in Anhui].

Science.gov (United States)

Zheng, Han; Xu, Tao; Li, Chuan-Run; Sun, Xiao-Mei; Xiang, Long; Zhao, Wei-Bo; Liu, He-Ling; Zhou, Jian-Li; Yang, Qing-Shan; Peng, Dai-Yin

2016-07-01

Herbarium specimens are the basis for the plant classification and indispensable media in teaching, scientific research and resources investigation. They have also played an important role in identifying and producing traditional Chinese medicine. High-quality herbarium specimens shall meet high requirements for integrity, smoothness, color and fabricating efficiency. Therefore, we designed a rapid setting and drying device for herbarium specimens, which could make the herbarium specimens smooth, colorful and not easy to mildew. In this paper, we pointed out the deficiency of traditional methods in making herbarium specimens, and introduced the structure and working principle of the device. Besides, we also discussed the effect of the device in setting and drying herbarium specimens and its application in the fourth national survey of the Chinese material medica resources (CMMR) in Anhui province. As a result, the device provides new ideas for producing herbarium specimens, with a reasonable design, good uniformity, high efficiency, safety and portability, and so is worthy of promotion and application in the national survey of CMMR. Copyright© by the Chinese Pharmaceutical Association.

Medieval Theatre: It's More Fun than It Looks.

Science.gov (United States)

Fitzhugh, Mike

1996-01-01

Explores production ideas for plays other than works by Shakespeare, including medieval plays such as the "Wakefield Noah" by the Wakefield Master. Lists some questions to consider when deciding to perform a medieval play. (PA)

Interest in medieval accounts: Examples from England, 1272-1340

OpenAIRE

Adrian R. Bell; Chris Brooks; Tony Moore

2008-01-01

Research into medieval interest rates has been hampered by the diversity of terms and methods used by historians, creating serious misconceptions in the eporting of medieval interest rates, which have then been taken at face value by later scholars. This has had important repercussions on the wider debate on the credit risk of different forms of medieval governments and the costs of borrowing as a bar to investment. This paper seeks to establish a standardised methodology to accurately calcul...

Pulp fictions of medieval England: Essays in popular romance

OpenAIRE

McDonald, Nicola

2004-01-01

Middle English popular romance is the most audacious and compendious testimony to the imaginary world of the English Middle Ages. Yet, with few exceptions, it remains under read and under studied. Pulp fictions of medieval England demonstrates that popular romance merits and rewards serious critical attention and that it is crucial to our understanding of the complex and conflicted world of medieval England. Pulp fictions of medieval England comprises ten essays on individual romances that, w...

The Barbarian North in Medieval Imagination

DEFF Research Database (Denmark)

Jensen-Rix, Robert William

This book examines the sustained interest in legends of the pagan and peripheral North, tracing and analyzing the use of an ‘out-of-Scandinavia’ legend (Scandinavia as an ancestral homeland) in a wide range of medieval texts from all over Europe, with a focus on the Anglo-Saxon tradition. The pagan...... origins, showing how an ‘out-of-Scandinavia’ legend can be found in works by several familiar writers including Jordanes, Bede, ‘Fredegar’, Paul the Deacon, Freculph, and Æthelweard. The book investigates how legends of northern warriors were first created in classical texts and since re-calibrated to fit...... the disciplines of poetry, history, rhetoric, linguistics, and archaeology. After years of intense critical interest in medieval attitudes towards the classical world, Africa, and the East, this first book-length study of ‘the North’ will inspire new debates and repositionings in medieval studies....

Representations of Lancet or Phlebotome in Serbian Medieval Art.

Science.gov (United States)

Pajić, Sanja; Jurišić, Vladimir

2015-01-01

The topic of this study are representations of lancet or phlebotome in frescoes and icons of Serbian medieval art. The very presence of this medical instrument in Serbian medieval art indicates its usage in Serbian medical practices of the time. Phlebotomy is one of the oldest forms of therapy, widely spread in medieval times. It is also mentioned in Serbian medical texts, such as Chilandar Medical CodexNo. 517 and Hodoch code, i.e. translations from Latin texts originating from Salerno-Montpellier school. Lancet or phlebotome is identified based on archaeological finds from the Roman period, while finds from the Middle Ages and especially from Byzantium have been scarce. Analyses of preserved frescoes and icons has shown that, in comparison to other medical instruments, lancet is indeed predominant in Serbian medieval art, and that it makes for over 80% of all the representations, while other instruments have been depicted to a far lesser degree. Examination of written records and art points to the conclusion that Serbian medieval medicine, both in theory and in practice, belonged entirely to European traditions of the period.

Patterns and prevalence of violence-related skull trauma in medieval London.

Science.gov (United States)

Krakowka, Kathryn

2017-11-01

This study aims to identify the patterns and prevalence of violence-related skull trauma (including the cranium and mandible) among a large sample of skeletons from medieval London (1050-1550 AD). In total, data from 399 skulls, representing six different sites from across medieval London, were analyzed for evidence of trauma and assessed for the likelihood that it was caused by violence. The sites include the three parish cemeteries of St Nicholas Shambles (GPO75), St Lawrence Jewry (GYE92), and St Benet Sherehog (ONE94); the two monastic houses of London Blackfriars (PIC87) and St Mary Graces (MIN86); and the early inmate cemetery from the medieval hospital of St Mary Spital (NRT85). The overall findings suggest that violence affected all aspects of medieval London society, but how that violence was characterized largely depended on sex and burial location. Specifically, males from the lay cemeteries appear to have been the demographic most affected by violence-related skull injuries, particularly blunt force trauma to the cranial vault. Using both archaeological and historical evidence, the results suggest that violence in medieval London may have been more prevalent than in other parts of medieval England, particularly rural environments, but similar to other parts of medieval Europe. However, more studies focusing on medieval trauma, and violence specifically, need to be carried out to further strengthen these results. In particular, males from the lay cemeteries were disproportionately affected by violence-related trauma, especially blunt force trauma. It perhaps indicates a means of informal conflict resolution as those of lower status did not always have the newly established medieval legal system available to them. © 2017 Wiley Periodicals, Inc.

Gioacchino Volpe and the medieval religious movements

Directory of Open Access Journals (Sweden)

Enrico Artifoni

2007-12-01

Full Text Available This article is a widened version of a lecture held in 2005 at the congress: ‘Gioacchino Volpe between past and present’, issued in the volume edited by R. Bonuglia (Rome 2007. It analyzes the main topics present in the work by Gioacchino Volpe: Movimenti religiosi e sette ereticali nella società medievale italiana (secoli XI-XIV (‘Religious movements and heretical sects in Italian Medieval society (11th-14th century', of 1922, and connects such essay to the author’s interests for ‘social’ history in the period after the 11th century. It also casts light on the influence of  Volpe’s thesis on many Italian Medieval scholars, who studied the medieval heresies over the 20th century (Morghen, Dupré Theseider, Manselli, Violante.

Exploring the Middle Ages with the Medieval Map.

Science.gov (United States)

Parry, Joseph D.

1998-01-01

Illustrates how medieval maps provide a means for studying the Middle Ages by allowing students to explore the ideology and representations of the medieval world conveyed by the maps. Explains that students also can compare the maps with literature from the same time period to further analyze the representations of the culture. (CMK)

Renewing Audience Response in Study of Medieval Literature.

Science.gov (United States)

Harrington, David V.

Although modern readers often find the interpretation of medieval literature difficult, they should be encouraged to use their imagination to resolve the dilemmas they encounter. Often, these are the same issues with which medieval audiences had to wrestle and which the poets intended to raise. W. Iser's and H. R. Jauss's principles of…

Magna Carta: Teaching Medieval Topics for Historical Significance

Science.gov (United States)

Metzger, Scott Alan

2010-01-01

The Middle Ages are an immensely important era in the Western experience. Unfortunately, medieval studies are often marginalized or trivialized in school curriculum. With the approach of the 800th anniversary of Magna Carta, the famous charter of rights from medieval England, one has a timely and useful example for considering what a focus on…

Medieval herbal iconography and lexicography of Cucumis (cucumber and melon, Cucurbitaceae) in the Occident, 1300-1458.

Science.gov (United States)

Paris, Harry S; Janick, Jules; Daunay, Marie-Christine

2011-09-01

The genus Cucumis contains two species of important vegetable crops, C. sativus, cucumber, and C. melo, melon. Melon has iconographical and textual records from lands of the Mediterranean Basin dating back to antiquity, but cucumber does not. The goal of this study was to obtain an improved understanding of the history of these crops in the Occident. Medieval images purportedly of Cucumis were examined, their specific identity was determined and they were compared for originality, accuracy and the lexicography of their captions. The manuscripts having accurate, informative images are derived from Italy and France and were produced between 1300 and 1458. All have an illustration of cucumber but not all contain an image of melon. The cucumber fruits are green, unevenly cylindrical with an approx. 2:1 length-to-width ratio. Most of the images show the cucumbers marked by sparsely distributed, large dark dots, but images from northern France show them as having densely distributed, small black dots. The different size, colour and distribution reflect the different surface wartiness and spininess of modern American and French pickling cucumbers. The melon fruits are green, oval to serpentine, closely resembling the chate and snake vegetable melons, but not sweet melons. In nearly all manuscripts of Italian provenance, the cucumber image is labelled with the Latin caption citruli, or similar, plural diminuitive of citrus (citron, Citrus medica). However, in manuscripts of French provenance, the cucumber image is labelled cucumeres, which is derived from the classical Latin epithet cucumis for snake melon. The absence of melon in some manuscripts and the expropriation of the Latin cucumis/cucumer indicate replacement of vegetable melons by cucumbers during the medieval period in Europe. One image, from British Library ms. Sloane 4016, has a caption that allows tracing of the word 'gherkin' back to languages of the geographical nativity of C. sativus, the Indian

Medieval Pictorial Art and Medieval Spanish Literature: A Case in Point for the Use of the Visual Arts in the Literature Class.

Science.gov (United States)

Bergstrom, Stanford E.

1991-01-01

An exploration of the connection between literature and the visual arts and its application in the foreign language literature class includes an illustration of how a medieval literary Spanish masterpiece becomes more clear when the text is compared with medieval pictorial art pieces. (four references) (Author/CB)

Insight into the Fulnek Church and Parish Medieval Building Chronology

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Augustinková Lucie

2017-06-01

Full Text Available The church of the Holy Trinity and parish in Fulnek was for nearly four centuries an Augustinian canonry and collegiate church (1293-1389. The medieval church and parish building chronology, however, have not been thus far established. From research between 2015 and 2016 we have been able to identify medieval portions of the buildings, clarify the site medieval construction phases and date the parish buildings (formerly the canonry from dendrochronological analysis of embedded wooden scaffolding.

Skin pathology and medical prognosis in medieval Europe: the secrets of Hippocrates.

Science.gov (United States)

Ackerman Smoller, L

2000-12-01

This article analyzes a medieval text known as The Secrets of Hippocrates. Neither secret (because of its wide circulation in manuscript and print) nor by Hippocrates, the work offered readers a means of offering a prognosis of impending death based on observable signs on the skin. Although the aphorisms that make up the text make little sense in a modern medical understanding, the Secrets of Hippocrates fits well within three medieval traditions: the tradition of secrets literature, the medieval medical tradition, and the tradition of medieval Christian views about the body. First, like other books of secrets, a genre to whose conventions the text closely adheres, the Secrets of Hippocrates offered a shortcut to socially useful knowledge: the ability to offer an accurate medical prognosis. Second, the treatise corresponded to the medieval physician's concern for the so-called nonnaturals, such as diet and exercise. Third, it fit with a medieval Christian notion that sickness and sin were related, as were sin and ugliness. Just as a leper's deformities were a window to his sinful soul, so skin pathologies could clue a medieval physician to the lethal disease hidden inside the body.

Effect of intracanal medicament on bond strength of fibre posts

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Huda Melike Bayram

2016-07-01

Full Text Available The aim of this study was to evaluate the effect of calcium hydroxide (CH, triple antibiotic paste (TAP and double antibiotic paste (DAP on the push-out bond strengths of three different self-adhesive resin cements. Forty-eight single-rooted human maxillary central incisors were selected. The crowns were removed and the root canals were performed. After the irrigation protocols, the post space was prepared. The teeth were then randomly divided into a control group (no intracanal medicament and three medicament groups (n = 12 for each group. After three weeks, the medicaments were removed using 17% ethylenediaminetetraacetic acid, 2.5% sodium hypochlorite and EndoActivator agitation. The teeth were divided into three subgroups according to the fibre-post luting cement: Maxcem Elite, RelyX Unicem and BisCem. The specimens were sectioned and the push-out test was performed. One-way analysis of variance and Tukey's post hoc tests were used for statistical analyses. Regarding the type of cement, BisCem had significantly lower bond strength values than Maxcem and RelyX. There was no significant difference between the bond strength values of Maxcem and RelyX (p > 0.05. The TAP-RelyX group had the highest bond strength value and the DAP-BisCem group had the lowest bond strength value. RelyX and Maxcem had higher bond strength to root canal dentin than BisCem. The bond strength of BisCem, RelyX and Maxcem was not negatively affected by the use of DAP, CH and TAP as intracanal medicaments.

The Medieval Swedish Horror Ballad in the Romantic Era

DEFF Research Database (Denmark)

Fyhr, Mattias

2014-01-01

In the late 18th century the Horror Ballad became popular in Sweden. The rediscovery of medieval tales and ballads inspired the Romantic authors. Clas Livijn uses the medieval folksong of "Hafsfrun" in his dramatic play of the same title (1806). In Livijn’s own library we also find many......” by Baggesen, in turn based on German and English sources. Anna Maria Lenngren followed with several ballads, often based on Danish sources. One more purely Swedish medieval ballad is “Varulven”. From 1810 unto 1971 thirteen versions of this Swedish ballad was discovered and printed. I place the focus...

Geriatric management in medieval Persian medicine

Science.gov (United States)

Emami, Morteza; Sadeghpour, Omid; Zarshenas, Mohammad M.

2013-01-01

In Iran, a large group of patients are elderly people and they intend to have natural remedies as treatment. These remedies are rooted in historical of Persian and humoral medicine with a backbone of more than 1000 years. The current study was conducted to draw together medieval pharmacological information related to geriatric medicine from some of the most often manuscripts of traditional Persian medicine. Moreover, we investigated the efficacy of medicinal plants through a search of the PubMed, Scopus and Google Scholar databases. In the medieval Persian documents, digestible and a small amount of food such as chicken broth, honey, fig and plum at frequent intervals as well as body massage and morning unctioning are highly recommended. In the field of pharmacotherapy, 35 herbs related to 25 families were identified. Plants were classified as tonic, anti-aging, appetizer, memory and mood enhancer, topical analgesic and laxative as well as health improvement agents. Other than historical elucidation, this paper presents medical and pharmacological approaches that medieval Persian practitioners applied to deal with geriatric complications. PMID:24381461

Use of digital applications in the medicament calculation education for nursing

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Francisco Gilberto Fernandes Pereira

Full Text Available Objective.To evaluate the influence of the use of digital applications in medicament calculation education for nursing students. Methods. An experimental study was developed with a sample of 100 nursing students, who were divided randomly into two groups (use of the Calculation Medicines - CalcMed application - available free on the Internet, n=50 and control (conventional method of the calculator use and pre-math skills, n=50. Both groups were assessed before and after the application of the teaching strategy through a test with ten specific questions of medicament calculations. Results. The study group showed a mean score of 8.14 versus an average of 5.02 in the control group. The average time of test execution was faster in the study group compared to the control group (15.7 versus 38.9 minutes. Conclusion. The strategy of using this application positively influences learning and enables greater security in the implementation of medicament calculations.

Acta informatica medica is indexed in pubmed and archived in pubmed central.

Science.gov (United States)

Masic, Izet

2013-03-01

Acta Informatica Medica journal has been accepted for archiving in PubMed Central from 2011 onward. The journal started in 1993 as the official journal of the Society for Medical Informatics of Bosnia and Herzegovina. During the last 3 years, Acta Informatica Medica has een included in almost all prestigious online databases, including PubMed, Scopus and EMBASE. The 20th volume of the journal is fully international, with papers from 18 countries.

The long-term impact of developmental stress. Evidence from later medieval and post-medieval London (AD1117-1853).

Science.gov (United States)

Watts, Rebecca

2015-12-01

Episodes of ill-health in childhood can predispose affected individuals to further periods of illness and early adult mortality. This study uses nonspecific indicators of stress to examine how growth disruptions during infancy/early childhood, and late childhood/early adolescence affected adult longevity in later medieval and post-medieval London. Hazards analysis was used to evaluate the effect of linear enamel hypoplasia (LEH) and the size of the anteroposterior (AP) and transverse (TR) diameters of the vertebral neural canal (VNC) on adult age-at-death. This was applied to skeletal samples from later medieval (n = 461) and post-medieval (n = 480) London. Growth disruptions during infancy/early childhood (LEH and AP VNC diameters) were not associated with longevity, or with impaired growth at later stages of development (TR VNC diameters). Growth disruptions during late childhood/early adolescence (TR VNC diameters) were associated with a significantly increased risk of adult mortality. Macroscopic hypoplasia represent short periods of stress during infancy/early childhood which did not disrupt future investments in growth or cause long-term damage to health. Small TR diameters represent chronic stress during late childhood/early adolescence which resulted in greater susceptibility to infections and increased risk of mortality. These interactions were influenced by sex and socioeconomic status, suggesting that socioeconomic circumstances in both childhood and adult life could influence exposure and resistance to stressors. © 2015 Wiley Periodicals, Inc.

The Challenge of Folklore to Medieval Studies

OpenAIRE

John Lindow

2018-01-01

When folklore began to emerge as a valid expression of a people during the early stages of national romanticism, it did so alongside texts and artifacts from the Middle Ages. The fields of folklore and medieval studies were hardly to be distinguished at that time, and it was only as folklore began to develop its own methodology (actually analogous to medieval textual studies) during the nineteenth century that the fields were distinguished. During the 1970s, however, folklore adopted a wholly...

Materias activas permitidas en producción integrada. Frutales de hueso 2016

OpenAIRE

Departamento de Desarrollo Rural y Sostenibilidad

2016-01-01

Materias activas admitidas en producción integrada para frutales de hueso y las restricciones de uso. Las materias activas de nueva inclusión se indican con asterisco y son admitidas a partir del 1 de enero de 2016.

Premaxillary hyperdontia in medieval Norwegians: a radiographic study.

Science.gov (United States)

Stermer Beyer-Olsen, E M

1989-11-01

An excavation of a part of the graveyard of St Olav's church, Trondheim, Norway, uncovered 389 tombs from the medieval period (1100-1600). Radiographic examination of 140 skulls with an intact premaxilla revealed hyperdontia in the form of a mesiodens in two (1.4%) cases. This is within the same range as similar medieval and present Nordic populations. Change in functional pattern does not seem to influence the prevalence.

The Medieval Dublin Project: A Case Study

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Niall O'hOisin

2010-04-01

Full Text Available This paper provides an overview of the Medieval Dublin Project. It covers the development and release of the DVD ‘Medieval Dublin: From Vikings to Tudors (Schools Edition,’ and outlines the major virtual and interactive features developed for that release. The paper also covers the collaboration that took place between the DVD development team and the academic community and discusses the ways in which 3D visualisations, timelines, interactivity and character-based storytelling were used to present Dublin’s archaeological heritage in an engaging and interesting way

Anthony Davenport. Medieval Narrative – An Introduction

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Richard TRIM

2005-10-01

Full Text Available This latest book by Tony Davenport represents not only a very useful guide to the different types of narrative associated with the Middle Ages but also succinctly describes their origins in Antiquity as well as linking up the various genres of medieval story-telling to present-day fiction in prose and film. The introductory pages thus give a global picture of narrative both before and after the medieval period and the Middle Ages are thereby not left in a vacuum. Although the focus is on Engl...

Episodes in the mathematics of medieval Islam

CERN Document Server

Berggren, J L

2016-01-01

This book presents an account of selected topics from key mathematical works of medieval Islam, based on the Arabic texts themselves. Many of these works had a great influence on mathematics in Western Europe. Topics covered in the first edition include arithmetic, algebra, geometry, trigonometry, and numerical approximation; this second edition adds number theory and combinatorics. Additionally, the author has included selections from the western regions of medieval Islam—both North Africa and Spain. The author puts the works into their historical context and includes numerous examples of how mathematics interacted with Islamic society.

Greek Astronomy and the Medieval Arabic Tradition

Science.gov (United States)

Saliba, George

2002-07-01

Islamic scholars of the Middle Ages are often credited with preserving the scientific writings of Antiquity through the Dark Ages of Europe. Saliba argues that the medieval Islamic astronomers did far more—actually correcting and improving on Greek astronomy by creating new mathematical tools to explain the motions of celestial objects. These tools were so useful that Copernicus appears to have borrowed them for use in his heliocentric cosmology. In this new light, the medieval Islamic astronomers played a fundamental role in the scientific revolution that was forged in Europe during the Renaissance.

Research output in medieval and crusades studies 1981-2011

DEFF Research Database (Denmark)

Nielsen, Torben Kjersgaard

2017-01-01

This article investigates the numerical research output of crusade studies over the past thirty years. The article compares its findings to the output of medieval studies in general in the same period. It shows in detail how the applied bibliometric statistics are generated and elaborates on some...... of the methodological considerations necessary in carrying out this kind of quantitative research. On the basis of bibliometric statistics generated from the International Medieval Bibliography (IMB) and Bibliographie de Civilisation Médiévale (BCM), the article identifies a numeric decrease in research output both...... in crusade studies in particular and in medieval studies in general. The article proposes further discussion on the “why” and “how” of this somewhat surprising result....

Sex differentials in frailty in medieval England.

Science.gov (United States)

DeWitte, Sharon N

2010-10-01

In most modern populations, there are sex differentials in morbidity and mortality that favor women. This study addresses whether such female advantages existed to any appreciable degree in medieval Europe. The analyses presented here examine whether men and women with osteological stress markers faced the same risks of death in medieval London. The sample used for this study comes from the East Smithfield Black Death cemetery in London. The benefit of using this cemetery is that most, if not all, individuals interred in East Smithfield died from the same cause within a very short period of time. This allows for the analysis of the differences between men and women in the risks of mortality associated with osteological stress markers without the potential confounding effects of different causes of death. A sample of 299 adults (173 males, 126 females) from the East Smithfield cemetery was analyzed. The results indicate that the excess mortality associated with several osteological stress markers was higher for men than for women. This suggests that in this medieval population, previous physiological stress increased the risk of death for men during the Black Death to a greater extent than was true for women. Alternatively, the results might indicate that the Black Death discriminated less strongly between women with and without pre-existing health conditions than was true for men. These results are examined in light of previous analyses of East Smithfield and what is known about diet and sexually mediated access to resources in medieval England. © 2010 Wiley-Liss, Inc.

The origins of intensive marine fishing in medieval Europe: the English evidence.

Science.gov (United States)

Barrett, James H.; Locker, Alison M.; Roberts, Callum M.

2004-01-01

The catastrophic impact of fishing pressure on species such as cod and herring is well documented. However, the antiquity of their intensive exploitation has not been established. Systematic catch statistics are only available for ca.100 years, but large-scale fishing industries existed in medieval Europe and the expansion of cod fishing from the fourteenth century (first in Iceland, then in Newfoundland) played an important role in the European colonization of the Northwest Atlantic. History has demonstrated the scale of these late medieval and post-medieval fisheries, but only archaeology can illuminate earlier practices. Zooarchaeological evidence shows that the clearest changes in marine fishing in England between AD 600 and 1600 occurred rapidly around AD 1000 and involved large increases in catches of herring and cod. Surprisingly, this revolution predated the documented post-medieval expansion of England's sea fisheries and coincided with the Medieval Warm Period--when natural herring and cod productivity was probably low in the North Sea. This counterintuitive discovery can be explained by the concurrent rise of urbanism and human impacts on freshwater ecosystems. The search for 'pristine' baselines regarding marine ecosystems will thus need to employ medieval palaeoecological proxies in addition to recent fisheries data and early modern historical records. PMID:15590590

Simultaneous Determination of Flavonols and Terpene Lactones in ...

African Journals Online (AJOL)

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing ... were collected following oral administration of four different preparations and the ... disadvantages. ..... biloba leaf extracts to rats via different routes of.

Medieval and Renaissance Music Conference, Birmingham 3.–6. 7. 2014

Czech Academy of Sciences Publication Activity Database

Mráčková, Veronika; Baťa, J.

2014-01-01

Roč. 51, 3-4 (2014), s. 414-417 ISSN 0018-7003. [Medieval and Renaissance Music Conference. Birmingham, 03.07.2014-06.07.2014] Institutional support: RVO:68378076 Keywords : conference * medieval * music Subject RIV: AL - Art, Architecture, Cultural Heritage

The Pleasure of Discovery: Medieval Literature in Adolescent Novels Set in the Middle Ages.

Science.gov (United States)

Barnhouse, Rebecca

1999-01-01

Discusses three recent novels for young adults set in medieval times, illustrating several ways that modern writers incorporate medieval material into fiction. Argues that pairing such novels with medieval texts such as "Beowulf" and "The Canterbury Tales" offers opportunities to explore traditional literary topics while providing a gateway into…

The toxicology of Octopus maculosa: the blue-ringed octopus.

Science.gov (United States)

Bonnet, M S

1999-10-01

The biotoxicology of the Australian blue-ringed octopus is detailed with the view of introducing it as a remedy into the homoeopathic Materia Medica and stimulating the second step of proving this venom.

Crop Protection in Medieval Agriculture

NARCIS (Netherlands)

Zadoks, J.C.

2013-01-01

Mediterranean and West European pre-modern agriculture (agriculture before 1600) was by necessity ‘organic agriculture’. Crop protection is part and parcel of this agriculture, with weed control in the forefront. Crop protection is embedded in the medieval agronomy text books but specialised

KAEMPFEROL, A FLAVONOID COMPOUND FROM GYNURA MEDICA INDUCED APOPTOSIS AND GROWTH INHIBITION IN MCF-7 BREAST CANCER CELL

OpenAIRE

Yi, Xiaofang; Zuo, Jiangcheng; Tan, Chao; Xian, Sheng; Luo, Chunhua; Chen, Sai; Yu, Liangfang; Luo, Yucheng

2016-01-01

Background: Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica, kaempferol and its glycosides are the major constituents of G. medica. Here we investigated the growth inhibition and apoptosis induction effect of kaempferol extracted from G. medica. Materials and Methods: The inhibition effects of kaempferol were evaluated by...

Higher-than-present Medieval pine (Pinus sylvestris treeline along the Swedish Scandes

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Leif Kullman

2015-05-01

Full Text Available The upper treeline of Scots pine (Pinus sylvestris L. is renowned as a sensitive indicator of climate change and variability. By use of megafossil tree remains, preserved exposed on the ground surface, treeline shift over the past millennium was investigated at multiple sites along the Scandes in northern Sweden. Difference in thermal level between the present and the Medieval period, about AD 1000-1200, is a central, although controversial, aspect concerning the detection and attribution of anthropogenic climate warming. Radiocarbon-dated megafossil pines revealed that the treeline was consistently positioned as much as 115 m higher during the Medieval period than today (AD 2000-2010, after a century of warming and substantial treeline upshift. Drawing on the last-mentioned figure, and a lapse rate of 0.6 °C/100 m, it may be inferred that Medieval summer temperatures were about 0.7 °C warmer than much of the past 100 years. Extensive pine mortality and treeline descent after the Medieval warming peak reflect substantially depressed temperatures during the Little Ice Age. Warmer-than-present conditions during the Medieval period concur with temperature reconstructions from different parts of northern Fennoscandia, northwestern Russia and Greenland. Modern warming has not been sufficient to restore Medieval treelines. Against this background, there is little reason to view further modest warming as unnatural.

The risk of severe salicylate poisoning following the ingestion of topical medicaments or aspirin.

OpenAIRE

Chan, T. Y.

1996-01-01

Apart from isolated reports of severe salicylate poisoning after ingesting an unusually large amount of a medicinal oil, there are no published data on the threat arising from attempted suicide with topical medicaments containing methyl salicylate or wintergreen oil compared with aspirin tablets. In this retrospective study, the admission plasma salicylate concentrations and clinical presentations were compared in 80 subjects who had taken aspirin tablets (n = 42) or topical medicaments (n = ...

[Who were the healers in medieval Trondheim?].

Science.gov (United States)

Pape, K; Westin, S

1998-12-10

When Trondheim celebrated its millenium in 1997, this also marked a 1000 year-old medical tradition. In medieval times, sick and disabled people made their pilgrimage to the Nidaros cathedral and the grave of Saint Olav (995-1030). Working from the assumption that every organized society develops rituals and rules to deal with disease and death, we have looked for evidence of what kind of healers one would expect there were in medieval Trondheim up to the reformation in 1537. Sources include reports from archaeological excavations, written material of both medieval and more recent origin, buildings and objects, and living traditions. Three kinds of healer traditions can be identified: The popular and "wise" folk healers were based on traditional pre-Christian mythology and belief in natural forces. The charitable clerics emerged with Christianity. The "professional" wound healers evolved from the needs of the military, later to merge with the early barber surgeons. Traces of scientific traditions, the Salerno school and early European university medicine can be found in local texts, but there is no evidence of any university educated doctor practising in Trondheim before the 17th century.

Disintegration of monetary system of medieval Serbia

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Gnjatović Dragana

2014-01-01

Full Text Available The subject matter of this paper is the process of gradual disintegration of monetary system of medieval Serbia during the second half of the 14th and the first half of the 15th century. This period is characterized by an appearance of frequent usurpations of the ruling right to mint coinage by local landlords and the attempts of the rulers from Lazarević and Branković families to restore unified monetary system. Common debasements and restorations of silver coinage provoked economic instability and induced frequent turning backwards to the custom of using weighted silver instead of silver coins as commodity monetary standard. The aim of this paper is to explain the reasons for those phenomena. We apply qualitative, historical, empirical analysis where we consider money minting right holders and their decisions to debase and restore the value of silver dinars. We found that gradual disintegration of monetary system of medieval Serbian State continued until the fall of Serbian Despotate as a consequence of political instability following dissolution of medieval Serbian Empire and economic and financial exhaustion of Serbia by Ottoman suzerains.

Publications | Page 576 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Results 5751 - 5760 of 6341 ... Journal articles ... Report on workshops for the development of Materia Medica Regulations for ... Natural resources systems programme R8494 annex A : scientific report; tracking social capital outcomes and ...

Relationship of intracanal medicaments to endodontic flare-ups.

Science.gov (United States)

Trope, M

1990-10-01

The purpose of the study was to compare the effect of three intracanal medicaments on the incidence of post-instrumentation flare-ups. All teeth were instrumented to a predetermined minimum size using a 0.5% solution of sodium hypochlorite as the irrigant. Formocresol, Ledermix, and calcium hydroxide were placed in strict sequence irrespective of the presence or absence of symptoms or radiographic signs of apical periodontitis. The patients were given written post-operative instructions and a prescription for 600 mg ibuprofen to be taken if mild to moderate pain developed. If severe pain and/or swelling developed the patient was instructed to call the office immediately and was considered to have had a flare-up. Twelve flare-ups occurred in teeth with radiographic signs of apical periodontitis; none in teeth without periapical radiolucencies. Six of the twelve flare-ups occurred in retreatment cases and the other six occurred in teeth without previous endodontic treatment. No significant difference was found in the flare-up rate among the three intracanal medicaments.

Creato un nuovo stato della materia

CERN Document Server

Valsecchi, M C

2004-01-01

"Nei laboratori di tutto il mondo nascono continuamente nuovi materiali plastici, leghe di metallo, molecole progettate e assemblate atomo per atomo. I ricercatori dell'Istituto nazionale di fisica nucleare hanno fatto un passo in piu': manipolando i costituenti fondamentali dei nuclei atomici, hanno creato una nuova forma di materia, radicalmente diversa da quella che noi conosciamo" (1 page)

Books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval/Medieval and Renaissance Archaeology, Aarhus University, 1971-2014

DEFF Research Database (Denmark)

Roesdahl, Else

2015-01-01

Chronologically organized list of books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval and Renaissance Archaeology, Aarhus University, 1971-2014......Chronologically organized list of books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval and Renaissance Archaeology, Aarhus University, 1971-2014...

Historical fencing and scientific research medieval weapons: common ground

Directory of Open Access Journals (Sweden)

B. V. Hrynchyshyn

2015-07-01

We considered various approaches to the reconstruction of the historical fencing. It is proved that the activities of such societies has a positive effect on the process research of features of medieval weapons, fighting tactics of different periods The various approaches to the reconstruction of the historical fencing. Proved that the activities of such societies has a positive effect on the process research of features of medieval weapons, fighting tactics of different periods.

Proper Living - Exploring Domestic Ideals in Medieval Denmark

DEFF Research Database (Denmark)

Kristiansen, Mette Svart

2014-01-01

Houses frame homes, households, and daily life, and it is reasonable to suggest that ideas of domestic space in medieval society, and ideas of how to live in an orderly and acceptable manner in the eyes of one’s peers and oneself are reflected in domestic architecture, its layout, fittings......, and ornaments. This paper addresses ideas of proper living in affluent rural and urban milieus in medieval Denmark, particularly as they are expressed through houses, inventories, and murals, and it also addresses current challenges in understanding the materialized ideas based on excavations and analysis...

Locality and Distance in Cults of Saints in Medieval Norway

DEFF Research Database (Denmark)

Petersen, Nils Holger

2017-01-01

A discussion of the Norwegian medieval cult of the purported Irish St Sunniva, a cult in which holiness is seen as foreign and distant in the cultural memory of the saint.......A discussion of the Norwegian medieval cult of the purported Irish St Sunniva, a cult in which holiness is seen as foreign and distant in the cultural memory of the saint....

Yeast α-Glucosidase Inhibitory Phenolic Compounds Isolated from Gynura medica Leaf

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Chao Tan

2013-01-01

Full Text Available Gynura medica leaf extract contains significant amounts of flavonols and phenolic acids and exhibits powerful hypoglycemic activity against diabetic rats in vivo. However, the hypoglycemic active constituents that exist in the plant have not been fully elaborated. The purpose of this study is to isolate and elaborate the hypoglycemic activity compounds against inhibition the yeast α-glucosidase in vitro. Seven phenolic compounds including five flavonols and two phenolic acids were isolated from the leaf of G. medica. Their structures were identified by the extensive NMR and mass spectral analyses as: kaempferol (1, quercetin (2, kaempferol-3-O-β-D-glucopyranoside (3, kaempferol-3-O-rutinoside (4, rutin (5, chlorogenic acid (6 and 3,5-dicaffeoylquinic acid methyl ester (7. All of the compounds except 1 and 3 were isolated for the first time from G. medica. Compounds 1–7 were also assayed for their hypoglycemic activity against yeast α-glucosidase in vitro. All of the compounds except 1 and 6 showed good yeast α-glucosidase inhibitory activity with the IC50 values of 1.67 mg/mL, 1.46 mg/mL, 0.38 mg/mL, 0.10 mg/mL and 0.53 mg/mL, respectively.

Estado Vital de la Materia. Su origen, su evolución y su futuro.

OpenAIRE

J. Hernando Ordoñez

2001-01-01

En este artlculo se hacen algunas observaciones sobre un estado de la materia (estado vital), propuesto para reemplazar el de materia viva, que se usa habitualmente.

La materia en estado vital se organiza por una fuerza interna, que podríamos calificar como inteligente, que hace que los átomos se orienten y se organicen con determinada finalidad para fabricar células, para modelar órganos y, éstos, para culminar su obra integrándose con la armonía más admirable, par...

Social representations of memory and gender in later medieval England.

Science.gov (United States)

Kane, Bronach

2012-12-01

Social representations in later medieval culture have attracted little attention amongst psychologists, pre-dating the development of the so-called 'public sphere' in the eighteenth century. In addition, the association of pre-modern societies with 'traditional' modes of communication in social psychology places implicit limits on areas that may be studied through the lens of social representation theory. This article analyses the way in which knowledge circulated in late medieval society, noting initially the plural nature of representations of events and marginal groups, and the myriad channels through which beliefs were consolidated. In later medieval England perceptions of the past depended on collective and group memory, with customary rights and local histories forged through 'common knowledge', hearsay and the opinions of 'trustworthy men' of the village. The final section of this commentary provides an analysis of testimony from the late medieval church courts, in which witnesses articulated gender ideologies that reflected perceptions drawn from everyday life. Social representations of women were thus deployed in ecclesiastical suits, on the one hand supporting evidence of female witnesses and on the other justifying misogynistic stereotypes of women's behaviour.

The Image of Medieval Woman

Science.gov (United States)

Wade, Marjorie D.

1978-01-01

California State University offered a course concerning the roles and positions of women in medieval society as depicted in Middle High German literature. The course was open to all undergraduate students and required no prerequisites or knowledge of German. The content and structure of the course are outlined. (SW)

Population-Area Relationship for Medieval European Cities.

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Rudolf Cesaretti

Full Text Available Medieval European urbanization presents a line of continuity between earlier cities and modern European urban systems. Yet, many of the spatial, political and economic features of medieval European cities were particular to the Middle Ages, and subsequently changed over the Early Modern Period and Industrial Revolution. There is a long tradition of demographic studies estimating the population sizes of medieval European cities, and comparative analyses of these data have shed much light on the long-term evolution of urban systems. However, the next step-to systematically relate the population size of these cities to their spatial and socioeconomic characteristics-has seldom been taken. This raises a series of interesting questions, as both modern and ancient cities have been observed to obey area-population relationships predicted by settlement scaling theory. To address these questions, we analyze a new dataset for the settled area and population of 173 European cities from the early fourteenth century to determine the relationship between population and settled area. To interpret this data, we develop two related models that lead to differing predictions regarding the quantitative form of the population-area relationship, depending on the level of social mixing present in these cities. Our empirical estimates of model parameters show a strong densification of cities with city population size, consistent with patterns in contemporary cities. Although social life in medieval Europe was orchestrated by hierarchical institutions (e.g., guilds, church, municipal organizations, our results show no statistically significant influence of these institutions on agglomeration effects. The similarities between the empirical patterns of settlement relating area to population observed here support the hypothesis that cities throughout history share common principles of organization that self-consistently relate their socioeconomic networks to structured

Population-Area Relationship for Medieval European Cities.

Science.gov (United States)

Cesaretti, Rudolf; Lobo, José; Bettencourt, Luís M A; Ortman, Scott G; Smith, Michael E

2016-01-01

Medieval European urbanization presents a line of continuity between earlier cities and modern European urban systems. Yet, many of the spatial, political and economic features of medieval European cities were particular to the Middle Ages, and subsequently changed over the Early Modern Period and Industrial Revolution. There is a long tradition of demographic studies estimating the population sizes of medieval European cities, and comparative analyses of these data have shed much light on the long-term evolution of urban systems. However, the next step-to systematically relate the population size of these cities to their spatial and socioeconomic characteristics-has seldom been taken. This raises a series of interesting questions, as both modern and ancient cities have been observed to obey area-population relationships predicted by settlement scaling theory. To address these questions, we analyze a new dataset for the settled area and population of 173 European cities from the early fourteenth century to determine the relationship between population and settled area. To interpret this data, we develop two related models that lead to differing predictions regarding the quantitative form of the population-area relationship, depending on the level of social mixing present in these cities. Our empirical estimates of model parameters show a strong densification of cities with city population size, consistent with patterns in contemporary cities. Although social life in medieval Europe was orchestrated by hierarchical institutions (e.g., guilds, church, municipal organizations), our results show no statistically significant influence of these institutions on agglomeration effects. The similarities between the empirical patterns of settlement relating area to population observed here support the hypothesis that cities throughout history share common principles of organization that self-consistently relate their socioeconomic networks to structured urban spaces.

Protective effect of Radix Bupleuri extract against liver cirrhosis in rats

African Journals Online (AJOL)

1Department of Oncology, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430060, 2Department ... 1 Hospital; 4Institute of Chinese Materia Medica, Hubei Institute for Food and Drug .... cirrhosis model rats that were treated with oral.

The first coronation churches of medieval Serbia

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Kalić Jovanka

2017-01-01

Full Text Available The medieval ceremony of coronation as a rule took place in the most important church of a realm. The sites of the coronation of Serbian rulers before the establishment of the Žiča monastery church as the coronation church of Serbian kings in the first half of the thirteenth century have not been reliably identified so far. Based on the surviving medieval sources and the archaeological record, this paper provides background information about the titles of Serbian rulers prior to the creation of the Nemanjić state, and proposes that Stefan, son of the founder of the Nemanjić dynasty, was crowned king (1217 in the church of St Peter in Ras.

Medieval herbal iconography and lexicography of Cucumis (cucumber and melon, Cucurbitaceae) in the Occident, 1300–1458

Science.gov (United States)

Paris, Harry S.; Janick, Jules; Daunay, Marie-Christine

2011-01-01

Background The genus Cucumis contains two species of important vegetable crops, C. sativus, cucumber, and C. melo, melon. Melon has iconographical and textual records from lands of the Mediterranean Basin dating back to antiquity, but cucumber does not. The goal of this study was to obtain an improved understanding of the history of these crops in the Occident. Medieval images purportedly of Cucumis were examined, their specific identity was determined and they were compared for originality, accuracy and the lexicography of their captions. Findings The manuscripts having accurate, informative images are derived from Italy and France and were produced between 1300 and 1458. All have an illustration of cucumber but not all contain an image of melon. The cucumber fruits are green, unevenly cylindrical with an approx. 2:1 length-to-width ratio. Most of the images show the cucumbers marked by sparsely distributed, large dark dots, but images from northern France show them as having densely distributed, small black dots. The different size, colour and distribution reflect the different surface wartiness and spininess of modern American and French pickling cucumbers. The melon fruits are green, oval to serpentine, closely resembling the chate and snake vegetable melons, but not sweet melons. In nearly all manuscripts of Italian provenance, the cucumber image is labelled with the Latin caption citruli, or similar, plural diminuitive of citrus (citron, Citrus medica). However, in manuscripts of French provenance, the cucumber image is labelled cucumeres, which is derived from the classical Latin epithet cucumis for snake melon. The absence of melon in some manuscripts and the expropriation of the Latin cucumis/cucumer indicate replacement of vegetable melons by cucumbers during the medieval period in Europe. One image, from British Library ms. Sloane 4016, has a caption that allows tracing of the word ‘gherkin’ back to languages of the geographical nativity of C

Review of the Journal Acta Informatica Medica During Eight Year Period: 2008-2015.

Science.gov (United States)

Masic, Izet; Begic, Edin; Zunic, Lejla

2016-04-01

Acta Informatica Medica is official journal of the Academy for Medical Sciences of Bosnia and Herzegovina (from 2014 Acta Inform Med is published bimonthly). To evaluate journal "Acta Informatica Medica" in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2008-2015 (included 36 issues of journal). A total of 83 (average 13,8 articles per journal) articles were published in Acta Informatica Medica during 2015. Analyzing the type of articles, original articles are present in majority during 2015 (68,6%) (by analyzing last eight years, 310 (67,3%) were original). During 2015, 27,7% of articles were related to the applied of Health informatics in field of clinical medicine, 63,8% preclinical medicine and 8,5% to public health. Collaboration rate in 2015 was 0,84. Most often the time required for decision on acceptance of article in 2015 is between 50 and 60 days. Articles came from 16 countries. According to scimagojr.com for 2014, Acta Informatica Medica has SCImago Journal Rank 0,166, while Cites / Doc. (2 years) parameter (widely used as impact index) is 0,70. According to GoogleScholar, h5 index is 11 and h5 median is 19. We analyzed the Acta Informatica Medica by "Publish or Perish" software - H index was 14, g index was 19 and e-index was 10.39. Year after year the highest number of original articles are published. Although the period of revision of articles is acceptable, the period up to two months is certainly not long, the goal is to reduce this period. Although the magazine in mentioned field found its place, although it is indexed in numerous bases, including: PubMed, PubMed Central, SCOPUS, EMBASE, EBSCO, etc. The main goal for next year is that the magazine becomes part of the Web of Science. Imperative is further internationalization of the magazine.

Estado Vital de la Materia. Su origen, su evolución y su futuro.

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J. Hernando Ordoñez

2001-04-01

Full Text Available

En este artlculo se hacen algunas observaciones sobre un estado de la materia (estado vital, propuesto para reemplazar el de materia viva, que se usa habitualmente.

La materia en estado vital se organiza por una fuerza interna, que podríamos calificar como inteligente, que hace que los átomos se orienten y se organicen con determinada finalidad para fabricar células, para modelar órganos y, éstos, para culminar su obra integrándose con la armonía más admirable, para constituirse en organismos ya sea vegetales o animales.

Los planetas no tienen materia en estado vital; son masas que giran y giran, aparentemente sin finalidad conocida. En cambio, en nuestro planeta una buena parte de su masa adquirió vida, lo que llamamos biomasa, que abarca todos los organismos vivos, tanto vegetales como animales, en una proporción tal que si se pudiera calcular su peso nos daría cifras astronómicas.

Sobre el futuro de nuestro sol los científicos predicen que en los próximos 1.100 millones de años aumentará su luminosidad en un 10%. Esto sobre calentará a la Tierra como consecuencia de un severo efecto de invernadero. El agua de los mares y océanos hervirá y la vida en el planeta se extinguirá.

El universo está constituido por energía y materia, que pueden transformarse la una en la otra. La energía se presenta en varias fases, entre ellas, en la energía eléctrica, la luz y el calor, cuya naturaleza íntima nos es tan desconocida. La materia también está en varios estados: sólido, líquido, gaseoso, iónico, molecular y coloidal.

En el presente estudio intento hacer algunas observaciones sobre otro estado de la materia, que he denominado estado vital, nombre que propongo para reemplazar el de materia viva, que se usa habitualmente. Par hacerlo me baso en una consideración elemental: los átomos que integran la biomasa terrestre son los mismos que constituyen la materia inerte, no están vivos. En

[Freeze drying process optimization of ginger juice-adjuvant for Chinese materia medica processing and stability of freeze-dried ginger juice powder].

Science.gov (United States)

Yang, Chun-Yu; Guo, Feng-Qian; Zang, Chen; Cao, Hui; Zhang, Bao-Xian

2018-02-01

Ginger juice， a commonly used adjuvant for Chinese materia medica， is applied in processing of multiple Chinese herbal decoction pieces. Because of the raw materials and preparation process of ginger juice， it is difficult to be preserved for a long time， and the dosage of ginger juice in the processing can not be determined base on its content of main compositions. Ginger juice from different sources is hard to achieve consistent effect during the processing of traditional Chinese herbal decoction pieces. Based on the previous studies， the freeze drying of ginger juice under different shelf temperatures and vacuum degrees were studied， and the optimized freeze drying condition of ginger juice was determined. The content determination method for 6-gingerol， 8-gingerol， 10-gingerol and 6-shagaol in ginger juice and redissolved ginger juice was established. The content changes of 6-gingerol， 8-gingerol， 10-gingerol， 6-gingerol， 6-shagaol， volatile oil and total phenol were studied through the drying process and 30 days preservation period. The results showed that the freeze drying time of ginger juice was shortened after process optimization; the compositions basically remained unchanged after freeze drying， and there was no significant changes in the total phenol content and gingerol content， but the volatile oil content was significantly decreased( P <0.05). Within 30 days， the contents of gingerol， total phenol， and volatile oil were on the decline as a whole. This study has preliminarily proved the feasibility of freeze-drying process of ginger juice as an adjuvant for Chinese medicine processing. Copyright© by the Chinese Pharmaceutical Association.

Archaeological culture and medieval ethnic community: theoretical and methodical problems of correlation (the case of medieval Bulgaria

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Izmaylov Iskander L.

2014-09-01

Full Text Available Problems related to archaeological culture and ethnos comparison in the case of medieval Bulgaria are discussed in the article. According to the author, in recent years it has become evident that the traditional concept and methodology of the study of the Bulgars’ ethnogenesis and ethnic history are in contradiction with the facts accumulated. The methods of “archaeological ethno-genetics”, which dictated solving problems of ethnogenesis of the ancient population belonging to an archaeological culture in direct correlation with ethnicity, are currently being criticized. According to modern ideas about ethnos and ethnicity, ethnicity is based upon identity with a complex hierarchical nature. Contemporary methodology requires proceeding with the integrated study of the problems of ethnogenesis on the basis of archaeology and ethnology. This kind of analysis is based upon the study of the medieval Bulgar mentality as a source of information on key aspects of ethno-political ideas. The analysis of authentic historical sources, historiographical tradition elements and folklore materials makes it possible to reconstruct the basic ideas that were significant for an ethnic group. The archaeological culture of the population of Bulgaria is characterized by two clearly distinguished and interconnected elements – the common Muslim culture and that of the elite military “druzhina” (squad. These elements directly characterize the Bulgar ethno-political community. These theoretical conclusions and empirical research concerning the case of the medieval Bulgars’ ethnogenesis attest to the productivity of ethnological synthesis techniques on an interdisciplinary basis.

Ethno-diversity within current ethno-pharmacology as part of Israeli traditional medicine – A review

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Lev Efraim

2006-01-01

Full Text Available Abstract The Holy Land has absorbed millions of immigrants in recent centuries: Jews from East and West, Druze, Circassians, Muslim and Christian Arabs. The land is unique and diverse in geographical location and ethnic groups, and also in its cultural characteristics, including traditional medicine and use of materia medica. However, these traditions have waned over the years. The young state of Israel adopted a "melting pot" approach to fashion Jews from all over the world into Israelis. The traditional medicine and materia medica of different ethnic groups (Yemenite, Iranian, and Iraqi Jews are reviewed in this paper, as well as the ethno-botanical survey (first conducted in the 1980s, covering Bedouins, Druze, Circassians, and Muslim and Christian Arabs, and the matching ethno-pharmacological survey (conducted in the late 1990s covering the medicines sold in stores. Present-day healers are usually not young and are believed to be the end of the chain of traditional medical knowledge. The ethno-diversity of Israel is becoming blurred; modernity prevails, and ethnic characteristics are fading. The characteristic lines of traditional medicine and materia medica have hardly lasted three generations. A salient former dividing line between ethnic groups, namely their use of different medicinal substances, paradoxically becomes a bridge for conservative users of all groups and religions. Shops selling these substances have become centers for "nostalgia" and preserving the oriental heritage, traditional medicine, and medicinal substances!

[Hypochondria sine materia as a psychosomatic problem: a model of hypochondriac disorders realized in the cutaneous sphere].

Science.gov (United States)

Smulevich, A B; Dorozhenok, I Iu; Romanov, D V; L'vov, A N

2012-01-01

Hypochondria sine materia is a disorder with physical complains corresponding to no any somatic diagnosis. Hypochondria sine materia is a more complicated psychopathological condition compared to hypochondria cum materia. Hypochondria sine materia could be diagnosed not only in psychiatry, but mainly in general medicine. It is especially prevalent in dermatology. As a result of analysis of hypochondriac disorders involving cutaneous sphere in patients without dermatological diseases, a binary model of psychodermatological syndromes presenting with hypochondria sine materia in dermatology was developed. The binary structure of the psychodermatological syndromes includes secondary psychiatric symptoms based on primary coenesthesiopathic phenomena. The heterogeneous psychodermatological syndromes (cutaneous organ neurosis, impulsive excoriations syndrome, circumscripta hypochondria, coenesthesiopathic paranoia) could be arranged in a continuum of consecutively worsening conditions from neurotic to psychotic severity register. The syndromes differ in clinical and social prognosis requiring different approach to diagnosis and treatment.

Cereal production, high status and climate in Medieval Iceland

Science.gov (United States)

Erlendsson, Egill; Riddell, Scott

2017-04-01

At Hrísbrú (formerly the medieval Mosfell estate) in the Mosfell Valley, southwest Iceland, archaeologists have excavated a medieval skáli (hall) proposed to be the high status residence of a chieftain. This is indicated by the size of the skáli, artefacts (foreign goods), archaeofaunal (cattle/sheep bone) ratios and macrobotanical remains (cereal grain). The analysis of pollen from nearby natural contexts suggests that cereals were grown locally. Using multiple profile palynological approach, this paper examines if the apparent cereal production is representative of high status in the Icelandic context. First as a correlate by confirming that cereals were grown in association with the archaeological features characteristic of high status; secondly, as an indicator in its own right through comparison with other palynological datasets from inferred lower status farms. The presence or absence of cereal-type pollen (cf. barley) and other arable correlates was examined for each site. The results suggest that medieval cereal cultivation in the Mosfell Valley was confined to the landholding of the medieval Mosfell estate. This feature is seen as an attribute of the locale's greater status in relation to the other farms in Mosfell Valley. The abandonment of cereal cultivation at the Mosfell estate around AD 1200 is probably associated with interactions between changes in the nation's social power structure and how marginal cereal production in Iceland was (and is) in terms of climate.

Flavorings in Context: Spices and Herbs in Medieval Near East

OpenAIRE

Lewicka, Paulina B.

2011-01-01

Throughout history, the approach towards imported spices varied from culture to culture. In medieval and early post-medieval Europe, where spices became an exotic object of temporary desire, they were often used unskillfully and in a haphazard manner. In the Ottoman Constantinople, unlike in Europe, it was the moderate use of spices, and not overdosing them, that became a manifestation of status. As deliberate paragons of refinement, the Ottomans depreciated what they considered uncivilized w...

Genome-wide comparison of medieval and modern Mycobacterium leprae

DEFF Research Database (Denmark)

Schuenemann, Verena J; Singh, Pushpendra; Mendum, Thomas A

2013-01-01

Leprosy was endemic in Europe until the Middle Ages. Using DNA array capture, we have obtained genome sequences of Mycobacterium leprae from skeletons of five medieval leprosy cases from the United Kingdom, Sweden, and Denmark. In one case, the DNA was so well preserved that full de novo assembly...... origin for leprosy in the Americas, and the presence of an M. leprae genotype in medieval Europe now commonly associated with the Middle East. The exceptional preservation of M. leprae biomarkers, both DNA and mycolic acids, in ancient skeletons has major implications for palaeomicrobiology and human...

Medieval Nomads – Sixth International Conference on the Medieval History of the Eurasian Steppe (Szeged, Hungary, November 23–26, 2016

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Aleksandar Uzelac

2017-06-01

Full Text Available Sixth international conference dedicated to the Medieval History of the Eurasian Steppe took place in the Hungarian city of Szeged on November 23-26, 2016. The organizer of the event was MTA-SZTE (“Hungarian Academy of Sciences – University of Szeged” Turkological Research group of the departments of Altaic and Medieval Studies at the Faculty of Arts, University of Szeged. More than thirty scholars from Hungary, Russia, Turkey, China, Spain, Bulgaria and Serbia took part in this event. The working languages of the conference were English and Russian. Presented papers dealt with various aspects of the history of Eurasian nomads, from the Early Middle Ages up to the seventeenth century. Among them, several have been related to the history of the Golden Horde. The proceedings of the conference are planned to be published in 2017, as a separate volume of the journal Chronica – Annual of The Institute of History, University of Szeged. Considering the quality and variety of the papers, presented at this occasion, there is no doubt it will attract the attention of the growing community of researchers and scholars interested in the medieval history of Eurasia.

The Barbarian North in Medieval Imagination

DEFF Research Database (Denmark)

Jensen-Rix, Robert William

different medieval understandings of identity and ethnicity. Among other things, the ‘out-of-Scandinavia’ tale was exploited to promote a legacy of ‘barbarian’ vigor that could withstand the negative cultural effects of Roman civilization. This volume employs a variety of perspectives cutting across...

Variations of 57Fe hyperfine parameters in medicaments containing ferrous fumarate and ferrous sulfate

International Nuclear Information System (INIS)

Oshtrakh, M. I.; Novikov, E. G.; Dubiel, S. M.; Semionkin, V. A.

2010-01-01

Several commercially available medicaments containing ferrous fumarate (FeC 4 H 2 O 4 ) and ferrous sulfate (FeSO 4 ), as a source of ferrous iron, were studied using a high velocity resolution Mössbauer spectroscopy. A comparison of the 57 Fe hyperfine parameters revealed small variations for the main components in both medicaments indicating some differences in the ferrous fumarates and ferrous sulfates. It was also found that all spectra contained additional minor components probably related to ferrous and ferric impurities or to partially modified main components.

Limitations imposed by wearing armour on Medieval soldiers' locomotor performance

OpenAIRE

Askew, Graham N.; Formenti, Federico; Minetti, Alberto E.

2011-01-01

In Medieval Europe, soldiers wore steel plate armour for protection during warfare. Armour design reflected a trade-off between protection and mobility it offered the wearer. By the fifteenth century, a typical suit of field armour weighed between 30 and 50 kg and was distributed over the entire body. How much wearing armour affected Medieval soldiers' locomotor energetics and biomechanics is unknown. We investigated the mechanics and the energetic cost of locomotion in armour, and determined...

Genealogical relationships between early medieval and modern inhabitants of Piedmont.

Science.gov (United States)

Vai, Stefania; Ghirotto, Silvia; Pilli, Elena; Tassi, Francesca; Lari, Martina; Rizzi, Ermanno; Matas-Lalueza, Laura; Ramirez, Oscar; Lalueza-Fox, Carles; Achilli, Alessandro; Olivieri, Anna; Torroni, Antonio; Lancioni, Hovirag; Giostra, Caterina; Bedini, Elena; Pejrani Baricco, Luisella; Matullo, Giuseppe; Di Gaetano, Cornelia; Piazza, Alberto; Veeramah, Krishna; Geary, Patrick; Caramelli, David; Barbujani, Guido

2015-01-01

In the period between 400 to 800 AD, also known as the period of the Barbarian invasions, intense migration is documented in the historical record of Europe. However, little is known about the demographic impact of these historical movements, potentially ranging from negligible to substantial. As a pilot study in a broader project on Medieval Europe, we sampled 102 specimens from 5 burial sites in Northwestern Italy, archaeologically classified as belonging to Lombards or Longobards, a Germanic people ruling over a vast section of the Italian peninsula from 568 to 774. We successfully amplified and typed the mitochondrial hypervariable region I (HVR-I) of 28 individuals. Comparisons of genetic diversity with other ancient populations and haplotype networks did not suggest that these samples are heterogeneous, and hence allowed us to jointly compare them with three isolated contemporary populations, and with a modern sample of a large city, representing a control for the effects of recent immigration. We then generated by serial coalescent simulations 16 millions of genealogies, contrasting a model of genealogical continuity with one in which the contemporary samples are genealogically independent from the medieval sample. Analyses by Approximate Bayesian Computation showed that the latter model fits the data in most cases, with one exception, Trino Vercellese, in which the evidence was compatible with persistence up to the present time of genetic features observed among this early medieval population. We conclude that it is possible, in general, to detect evidence of genealogical ties between medieval and specific modern populations. However, only seldom did mitochondrial DNA data allow us to reject with confidence either model tested, which indicates that broader analyses, based on larger assemblages of samples and genetic markers, are needed to understand in detail the effects of medieval migration.

Genealogical relationships between early medieval and modern inhabitants of Piedmont.

Directory of Open Access Journals (Sweden)

Stefania Vai

Full Text Available In the period between 400 to 800 AD, also known as the period of the Barbarian invasions, intense migration is documented in the historical record of Europe. However, little is known about the demographic impact of these historical movements, potentially ranging from negligible to substantial. As a pilot study in a broader project on Medieval Europe, we sampled 102 specimens from 5 burial sites in Northwestern Italy, archaeologically classified as belonging to Lombards or Longobards, a Germanic people ruling over a vast section of the Italian peninsula from 568 to 774. We successfully amplified and typed the mitochondrial hypervariable region I (HVR-I of 28 individuals. Comparisons of genetic diversity with other ancient populations and haplotype networks did not suggest that these samples are heterogeneous, and hence allowed us to jointly compare them with three isolated contemporary populations, and with a modern sample of a large city, representing a control for the effects of recent immigration. We then generated by serial coalescent simulations 16 millions of genealogies, contrasting a model of genealogical continuity with one in which the contemporary samples are genealogically independent from the medieval sample. Analyses by Approximate Bayesian Computation showed that the latter model fits the data in most cases, with one exception, Trino Vercellese, in which the evidence was compatible with persistence up to the present time of genetic features observed among this early medieval population. We conclude that it is possible, in general, to detect evidence of genealogical ties between medieval and specific modern populations. However, only seldom did mitochondrial DNA data allow us to reject with confidence either model tested, which indicates that broader analyses, based on larger assemblages of samples and genetic markers, are needed to understand in detail the effects of medieval migration.

Meta-analysis as Statistical and Analytical Method of Journal's Content Scientific Evaluation.

Science.gov (United States)

Masic, Izet; Begic, Edin

2015-02-01

A meta-analysis is a statistical and analytical method which combines and synthesizes different independent studies and integrates their results into one common result. Analysis of the journals "Medical Archives", "Materia Socio Medica" and "Acta Informatica Medica", which are located in the most eminent indexed databases of the biomedical milieu. The study has retrospective and descriptive character, and included the period of the calendar year 2014. Study included six editions of all three journals (total of 18 journals). In this period was published a total of 291 articles (in the "Medical Archives" 110, "Materia Socio Medica" 97, and in "Acta Informatica Medica" 84). The largest number of articles was original articles. Small numbers have been published as professional, review articles and case reports. Clinical events were most common in the first two journals, while in the journal "Acta Informatica Medica" belonged to the field of medical informatics, as part of pre-clinical medical disciplines. Articles are usually required period of fifty to fifty nine days for review. Articles were received from four continents, mostly from Europe. The authors are most often from the territory of Bosnia and Herzegovina, then Iran, Kosovo and Macedonia. The number of articles published each year is increasing, with greater participation of authors from different continents and abroad. Clinical medical disciplines are the most common, with the broader spectrum of topics and with a growing number of original articles. Greater support of the wider scientific community is needed for further development of all three of the aforementioned journals.

[Medicaments and oral healthcare 4. Pharmacotherapy in (frail and care dependent) older people].

Science.gov (United States)

de Baat, C; van der Putten, G J; Visser, A; Vissink, A

2017-05-01

Polypharmacy is the consequence of multimorbidity. Both phenomena may cause functional limitations and/or frailty and/or care dependency in older people. In the human body, a medicament undergoes at least 3 important actions: absorption, distribution and elimination. These actions may proceed aberrantly in older people. Following interaction with receptors, a medicament triggers a chain reaction in the human body. The receptors and each link of the chain reaction may be subject to changes due to diseases as well as ageing. This, particularly, is the case with regard to medications directed towards the central nervous system and the cardiovascular system. Furthermore, interactions may occur between various medications mutually and between medications on the one hand and on the other hand food and water intake, self-medication with herbs, and diseases. Moreover, older people usually experience more adverse effects of medications when compared to younger people. This is due to altered body actions and reactions, polypharmacy and the many possible interactions. In older people, utilisation and intake of medications often give rise to problems that can be divided into medicament-related, patient-related, care- and care provider-related and other problems.

Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.

Directory of Open Access Journals (Sweden)

Verena J Schuenemann

2018-05-01

Full Text Available Studying ancient DNA allows us to retrace the evolutionary history of human pathogens, such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the oldest recorded and most stigmatizing diseases in human history. The disease was prevalent in Europe until the 16th century and is still endemic in many countries with over 200,000 new cases reported annually. Previous worldwide studies on modern and European medieval M. leprae genomes revealed that they cluster into several distinct branches of which two were present in medieval Northwestern Europe. In this study, we analyzed 10 new medieval M. leprae genomes including the so far oldest M. leprae genome from one of the earliest known cases of leprosy in the United Kingdom-a skeleton from the Great Chesterford cemetery with a calibrated age of 415-545 C.E. This dataset provides a genetic time transect of M. leprae diversity in Europe over the past 1500 years. We find M. leprae strains from four distinct branches to be present in the Early Medieval Period, and strains from three different branches were detected within a single cemetery from the High Medieval Period. Altogether these findings suggest a higher genetic diversity of M. leprae strains in medieval Europe at various time points than previously assumed. The resulting more complex picture of the past phylogeography of leprosy in Europe impacts current phylogeographical models of M. leprae dissemination. It suggests alternative models for the past spread of leprosy such as a wide spread prevalence of strains from different branches in Eurasia already in Antiquity or maybe even an origin in Western Eurasia. Furthermore, these results highlight how studying ancient M. leprae strains improves understanding the history of leprosy worldwide.

Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.

Science.gov (United States)

Schuenemann, Verena J; Avanzi, Charlotte; Krause-Kyora, Ben; Seitz, Alexander; Herbig, Alexander; Inskip, Sarah; Bonazzi, Marion; Reiter, Ella; Urban, Christian; Dangvard Pedersen, Dorthe; Taylor, G Michael; Singh, Pushpendra; Stewart, Graham R; Velemínský, Petr; Likovsky, Jakub; Marcsik, Antónia; Molnár, Erika; Pálfi, György; Mariotti, Valentina; Riga, Alessandro; Belcastro, M Giovanna; Boldsen, Jesper L; Nebel, Almut; Mays, Simon; Donoghue, Helen D; Zakrzewski, Sonia; Benjak, Andrej; Nieselt, Kay; Cole, Stewart T; Krause, Johannes

2018-05-01

Studying ancient DNA allows us to retrace the evolutionary history of human pathogens, such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the oldest recorded and most stigmatizing diseases in human history. The disease was prevalent in Europe until the 16th century and is still endemic in many countries with over 200,000 new cases reported annually. Previous worldwide studies on modern and European medieval M. leprae genomes revealed that they cluster into several distinct branches of which two were present in medieval Northwestern Europe. In this study, we analyzed 10 new medieval M. leprae genomes including the so far oldest M. leprae genome from one of the earliest known cases of leprosy in the United Kingdom-a skeleton from the Great Chesterford cemetery with a calibrated age of 415-545 C.E. This dataset provides a genetic time transect of M. leprae diversity in Europe over the past 1500 years. We find M. leprae strains from four distinct branches to be present in the Early Medieval Period, and strains from three different branches were detected within a single cemetery from the High Medieval Period. Altogether these findings suggest a higher genetic diversity of M. leprae strains in medieval Europe at various time points than previously assumed. The resulting more complex picture of the past phylogeography of leprosy in Europe impacts current phylogeographical models of M. leprae dissemination. It suggests alternative models for the past spread of leprosy such as a wide spread prevalence of strains from different branches in Eurasia already in Antiquity or maybe even an origin in Western Eurasia. Furthermore, these results highlight how studying ancient M. leprae strains improves understanding the history of leprosy worldwide.

The Case for Medieval Drama in the Classroom: An Approach through Performance.

Science.gov (United States)

Lieblein, Leanore; Pare, Anthony

1983-01-01

Argues that medieval drama in performance suggests a number of important issues about the nature of literature, particularly about the way narrative and dramatic art can express the life of a community. Presents a series of exercises that start with familiar, nonthreatening situations in order to approach the richness of medieval plays and the…

Micromorphological Approaches to the Formation and Biographies of Early Medieval Towns in Northwest Europe

DEFF Research Database (Denmark)

Wouters, Barbora

Even after decades of intensive research, the complex stratigraphy of many early medieval and Viking towns in continental Europe remains poorly understood. Debate continues about crucial aspects such as their origins, the changes they underwent through time and, in some cases, their supposed...... on - the youngest early medieval urban phases 7. Post-depositional transformations This framework makes it possible to gain a deeper, more detailed understanding of the sites’ evolution through time as well their spatial organisation, and to mutually compare them without losing sight of their individual...... idiosyncrasies. At the same time, this approach bypasses a generalising discourse of early medieval towns. By juxtaposing the results of these five case studies with existing debates on early medieval towns, a number of set historical narratives can be challenged....

Bread as Food and Medicament in Oribasius’ Writings

OpenAIRE

Kokoszko, Maciej; Jagusiak, Krzysztof; Dybała, Jolanta

2016-01-01

Treatises left by Oribasius (first and foremost his Collectiones medicae and Eclogae medicamentorum) preserve a vast body of information on the varieties of bread eaten in late antiquity, characterise them from the point of view of dietetics, list medical conditions in which a given variety is especially beneficial, and name medical preparations which include the product. The present study elaborates on Oribasius’ dietetic knowledge and his input into the development of dietetic discourse (na...

"Fossils" of practical medical knowledge from medieval Cairo.

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Lev, Efraim; Amar, Zohar

2008-09-02

To asses the scientific value of the practical medical fragments found in the Cairo Genizah (10th century), as a useful source for ethnopharmacological purposes (in exposing rare and usually inaccessible original medieval practical knowledge of medicinal substances to present-day researchers), and to reconstruct the practical drugs and their uses. A methodology distinguishing between theoretical (about 1500 fragments) and practical medical knowledge (about 230 fragments) was created and used. The information regarding the practical medicinal substances was extracted from prescriptions (140), lists of drugs (70) and few letters of physicians. The reconstructed lists of practical (278) and theoretical (414) drugs allow us to recognize and quantify the gap between them in medieval times (136). We propose that the data obtained from ancient prescriptions is comparable to ethnopharmacological surveys. The finding of plants such as myrobalan, saffron, licorice, spikenard and lentisk, all of which have scientifically proven anti-microbial/bacterial and anti-fungal activity, sheds a helpful light on the medical decision-making of the medieval practitioners in respect of the plants they applied as drugs. With the wealth of information meticulously assembled from these time capsules we expect to make a significant contribution to contemporary efforts at locating modern drugs in ancient roots and gauging their feasibility.

204: THE ROLE OF IMCI PROGRAM IN THE RATIONALIZATION OF MEDICAMENT USE IN PEDIATRICS

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Ahmad, Chreitah

2017-01-01

Background and aims Integrated management of childhood illness (IMCI) is an EBM guideline prepared by WHO and UNICEF guideline in primary health care for better assessment and management in pediatrics. The study was carried out to demonstrate the reduction of medicament prescription by the application of IMCI program in two months up to five years old children presenting with an infectious disease. Methods Before and after study was carried out in July 2012 at a pediatric E.R children who met with the inclusion criteria were rolled in: ▸ Consulting for infectious disease. ▸ With no anterior treatment with antibiotics. ▸ No need of hospitalization. In total 112 patients were assessed separately by two groups of doctors (classical approach vs. IMCI guideline). The two prescriptions of each patient were analyzed using Mac Nemar, comparison of proportion tests. Results 112 patients (64 boys, 48 girls) with cough, diarrhea, sore throat, otalgia and fever were studied. In total 280 medicaments were prescribed firstly vs. 160 medicaments with IMCI guideline (P<0.0001). There were 103 oral antibiotics prescribed vs. 28 with IMCI guideline (P<0.0001). There were 20 intra muscular injections prescribed (15 antibiotics) vs. 9 with IMCI guideline (P<0.02). Only 37 antibiotics were justified vs. 82 non-justified (p<0.0001). Conclusion the assessment and management by IMCI program for children age 2 months up to 5 years in outpatient clinic may contribute for a better prescription with a significant reduction in total medicament prescribed, in oral antibiotics and intra muscular injections.

On the Jewish Nature of Medieval Spanish Biblical Translations Linguistic Differences between Medieval and Post-Exilic Spanish Translations of the Bible

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Schwarzwald, Ora

2010-06-01

Full Text Available A linguistic comparison of medieval Spanish translations of the Hebrew Bible and the Constantinople and Ferrara post exilic Ladino translations reveals systematic lexical and grammatical variations. These differences can be explained by the population groups to which the translations were targeted: Christian for the medieval translations; Jewish (or former converso for the post-exilic ones. The conclusion is that the medieval translations are not Jewish in nature and could therefore not have been a source for the post-exilic versions which were based on oral tradition.

Una comparación lingüística de las traducciones hispano-medievales de la Biblia hebrea y las postexílicas de Constantinopla y Ferrara revela variaciones sistemáticas léxicas y gramaticales. Esas diferencias pueden explicarse por la audiencia a las que iban dirigidas dichas traducciones: cristiana, en el caso de las medievales; judía (o exconversa en el de las post-exílicas. La autora concluye que las traducciones medievales no son judías, por naturaleza, y en consecuencia, no podrían haber sido una fuente para las versiones post-exílicas que estaban basadas en la tradición oral.

[Caries of permanent dentition in medieval inhabitants of Wrocław].

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Staniowski, Tomasz; Dabrowski, Paweł; Gawlikowska-Sroka, Aleksandra

2011-01-01

The study of dentition plays an important role in the reconstruction of the diet and in assessment of the overall health and living conditions of paleopopulations. The aim of this study was to determine the condition of permanent dentition of medieval inhabitants of Wrocław basing on the prevalence and intensity of caries in permanent dentition. The material consisted of 1156 permanent teeth from 118 skulls recovered from two medieval cemeteries in Wrocław: the parish cemetery at the St. Elisabeth Church (13th-14th century) and the cemetery in Ołbin (12th-13th century). Two age classes were formed taking into account anthropologic assessment and group size. The younger class consisted of material up to the age of 35 years; the remaining skulls were assigned to the older class. The prevalence and incidence of caries was determined. The prevalence and intensity of caries was 56.91% and 15.7%, respectively. Carious lesions predominated in males and in the older age class. The prevalence and intensity of caries in permanent dentition did not differ from other medieval populations and increased with age. High prevalence of caries reflects a high proportion of carbohydrates in the diet of medieval inhabitants of Wrocław, their high socioeconomic status, and poor oral hygiene.

Ideal kingship in the late medieval world: The Ottoman case

OpenAIRE

Yelçe, Zeynep Nevin; Yelce, Zeynep Nevin

2003-01-01

The aim of this study is to examine the characteristics of the ideal ruler as seen through the eyes of the members of late medieval societies. Throughout the study, main features attributed to the ideal ruler in various cultures have been pursued. Comparing the concepts and attributes apparent in these cultures, it has become possible to talk about a single ideal of kingship as far as the "Christian" and "Muslim" realms of the late medieval era is concerned. The early Ottoman enterprise has b...

Un gobierno medieval en un mundo global.

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Gisele Becerra

2007-05-01

Full Text Available The Colegio Mayor de Nuestra Señora del Rosario is a unique case in the World of corporate governance enduring, by which this university, one of the most prestigious institutions in Colombia, could preserve its culture and medieval tradition in the election of their authorities and governance becoming a modern higher education institution that educate the future social leaders. Nova et Vetera – the New and the Old– the integration of today reality and dynamics, and its future projection, with the more ancient university tradition of the Medieval concept of “Universitas Scholarium” becoming a modern institution of 354 years old. These successful combinations produced by the continuity of traditional corporate governance since 1653 has empowered the institution and permit it to lead the most important intellectual, political and social changes of the country.

Medieval Universities, Legal Institutions, and the Commercial Revolution. NBER Working Paper No. 17979

Science.gov (United States)

Cantoni, Davide; Yuchtman, Noam

2012-01-01

We present new data documenting medieval Europe's "Commercial Revolution'' using information on the establishment of markets in Germany. We use these data to test whether medieval universities played a causal role in expanding economic activity, examining the foundation of Germany's first universities after 1386 following the Papal Schism. We…

Farm Studies and Post-Medieval Rural Archaeology in Denmark: Comments on the Past, the Present and the Future

DEFF Research Database (Denmark)

Kristiansen, Mette Svart

2012-01-01

legislation and administrative practice, has left the post-medieval cultural heritage in a rather peculiar and to some extent neglected position. This paper will address research on post-medieval rural buildings and farms in particular and discuss the current challenges within post-medieval rural archaeology...

Variations of {sup 57}Fe hyperfine parameters in medicaments containing ferrous fumarate and ferrous sulfate

Energy Technology Data Exchange (ETDEWEB)

Oshtrakh, M. I., E-mail: oshtrakh@mail.utnet.ru; Novikov, E. G. [Ural Federal University (The former Ural State Technical University-UPI), Faculty of Physical Techniques and Devices for Quality Control (Russian Federation); Dubiel, S. M. [AGH University of Science and Technology, Faculty of Physics and Computer Science (Poland); Semionkin, V. A. [Ural Federal University (The former Ural State Technical University-UPI), Faculty of Physical Techniques and Devices for Quality Control (Russian Federation)

2010-04-15

Several commercially available medicaments containing ferrous fumarate (FeC{sub 4}H{sub 2}O{sub 4}) and ferrous sulfate (FeSO{sub 4}), as a source of ferrous iron, were studied using a high velocity resolution Moessbauer spectroscopy. A comparison of the {sup 57}Fe hyperfine parameters revealed small variations for the main components in both medicaments indicating some differences in the ferrous fumarates and ferrous sulfates. It was also found that all spectra contained additional minor components probably related to ferrous and ferric impurities or to partially modified main components.

Two medieval doctors: Gilbertus Anglicus (c1180-c1250) and John of Gaddesden (1280-1361).

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Pearn, John

2013-02-01

Biographies of medieval English doctors are uncommon and fragmentary. The two best-known English medieval physicians were Gilbertus Anglicus and John of Gaddesden. This paper brings together the known details of their lives, compiled from extant biographies and from internal references in their texts. The primary records of their writings exist in handwritten texts and thereafter in incunabula from the time of the invention of printing in 1476. The record of the lives of these two medieval physicians can be expanded, as here, by the general perspective of the life and times in which they lived. Gilbertus Anglicus, an often-quoted physician-teacher at Montpellier, wrote a seven-folio Compendium medicinae in 1271. He described pioneering procedures used later in the emergent disciplines of anaesthetics, cosmetic medicine and travel medicine. Gilbertus' texts, used extensively in European medical schools, passed in handwritten copies from student to student and eventually were printed in 1510. John of Gaddesden, an Oxford graduate in Arts, Medicine and Theology, wrote Rosa Anglica, published circa 1314. Its detailed text is an exemplar of the mixture of received Hippocratic and Galenic lore compounded by medieval astronomy and religious injunction, which mixture was the essence of medieval medicine. The writings of both these medieval English physicians formed part of the core curriculum that underpinned the practice of medicine for the next 400 years.

Temporal trends in vertebral size and shape from medieval to modern-day.

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Juho-Antti Junno

Full Text Available Human lumbar vertebrae support the weight of the upper body. Loads lifted and carried by the upper extremities cause significant loading stress to the vertebral bodies. It is well established that trauma-induced vertebral fractures are common especially among elderly people. The aim of this study was to investigate the morphological factors that could have affected the prevalence of trauma-related vertebral fractures from medieval times to the present day. To determine if morphological differences existed in the size and shape of the vertebral body between medieval times and the present day, the vertebral body size and shape was measured from the 4th lumbar vertebra using magnetic resonance imaging (MRI and standard osteometric calipers. The modern samples consisted of modern Finns and the medieval samples were from archaeological collections in Sweden and Britain. The results show that the shape and size of the 4th lumbar vertebra has changed significantly from medieval times in a way that markedly affects the biomechanical characteristics of the lumbar vertebral column. These changes may have influenced the incidence of trauma- induced spinal fractures in modern populations.

advancing the frontiers of pharmacy profession to new horizons

African Journals Online (AJOL)

Prof.Thoithi

The practice of pharmacy has been changing over the years prompting pharmacists to explore new horizons. In many medical schools teaching of clinical pharmacology has been upgraded from the previous materia medica thus eroding the comparative advantage pharmacists previously enjoyed over their medical ...

Simultaneous Determination of Flavonols and Terpene Lactones in ...

African Journals Online (AJOL)

Lactones in Beagle Dog Plasma by Ultra-Performance ... School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China ... Purpose: To evaluate the pharmacokinetics of the major compounds in Ginkgo leaf dosage ... pharmacological effect. .... conversion factor was calculated as in Eq 1.

Trazando la materia oscura con cúmulos globulares

Science.gov (United States)

Forte, J. C.

Se describe la estrategia adoptada para mapear la distribución de materia oscura y bariónica en galaxias elípticas cuyos cúmulos globulares están siendo observados con los telescopios VLT y Gemini. Se ejemplifican los resultados con los datos obtenidos en el cúmulo de Fornax.

“I” of the author of the 12th century: rhetoric and subjectivity of medieval literature

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Dolgorukova Natalia Mikhailovna

2015-10-01

Full Text Available This article attempts to answer a series of questions relevant to the study of medieval literature: is it possible to create a typology of the medieval “I” and to distinguish rhetorical use of personal constructions from more subjective types which was the author's “I” in the 12th century. Is it possible to talk about subjectivity of medieval literature, and, if so, how is it expressed?

Medieval European medicine and Asian spices.

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Nam, Jong Kuk

2014-08-01

This article aimed to explain the reasons why Asian spices including pepper, ginger, and cinnamon were considered as special and valuable drugs with curative powers in the Medieval Europe. Among these spices, pepper was most widely and frequently used as medicine according to medieval medical textbooks. We analyzed three main pharmacology books written during the Middle Ages. One of the main reasons that oriental spices were widely used as medicine was due to the particular medieval medical system fundamentally based on the humoral theory invented by Hippocrates and Galen. This theory was modified by Arab physicians and imported to Europe during the Middle Ages. According to this theory, health is determined by the balance of the following four humors which compose the human body: blood, yellow bile, black bile, and phlegm. Each humor has its own qualities such as cold, hot, wet, and dry. Humoral imbalance was one of the main causes of disease, so it was important to have humoral equilibrium. Asian spices with hot and dry qualities were used to balance the cold and wet European diet. The analysis of several major medical textbooks of the Middle Ages proves that most of the oriental spices with hot and dry qualities were employed to cure diverse diseases, particularly those caused by coldness and humidity. However, it should be noted that the oriental spices were considered to be much more valuable and effective as medicines than the local medicinal ingredients, which were not only easily procured but also were relatively cheap. Europeans mystified oriental spices, with the belief that they have marvelous and mysterious healing powers. Such mystification was related to the terrestrial Paradise. They believed that the oriental spices were grown in Paradise which was located in the Far East and were brought to the Earthly world along the four rivers flowing from the Paradise.

Salving Distribution Information System on PT. Anugerah Argon Medica

OpenAIRE

Yunus, Halimah

2015-01-01

Medica's Argon godsend constitute moving firm at salving sell area filing system and its reporting is still utilize archives and ledger before utilizes.Data collecting on observational it utilizes to methodic observation, interview and `studi` is library.Meanwhile software development methods that is utilized is model Waterfall. Implementation of model Waterfall this was worded utilize `document`'s flowing charts, diagram context, `flow`'s data diagramdesignoutput` is input design databasedat...

[Status and future of natural resource for Chinese materia medica].

Science.gov (United States)

Ma, Xiao-jing; Guo, Juan; Tang, Jin-fu; Ma, Xiao-hui; Ma, Ying; Dai, Zhu-bo; Guo, Lan-ping; Huang, Lu-qi

2015-05-01

For thousands of years, the natural resource for Chinese materiamedica has been the foundation of the traditional Chinese medicine industry, which provides abundant medicine for human. In recent years, increasing demands and irrational exploitation led to a lot of problems such as rapid decrease of traditional Chinese herbs reserves, low quality of medicine and dismishing traditional cultures. These restricted the development of the traditional Chinese medicine. To solve these problems, scientists have done much work on investigating traditional Chinese medicine resources, exploring the metabolic pathway of bioactive ingredients, cultivating new varieties, and carrying out synthetic biology. These studies provided a theoretical basis for sustainable utilizationand future developmentof traditional Chinese medicine resources.

[Ecology suitability study of Chinese materia medica Gentianae Macrophyllae Radix].

Science.gov (United States)

Lu, You-Yuan; Yang, Yan-Mei; Ma, Xiao-Hui; Zhang, Xiao-Bo; Zhu, Shou-Dong; Jin, Ling

2016-09-01

This paper is aimed to predict ecology suitability distribution of Gentianae Macrophyllae Radix and search the main ecological factors affecting the suitability distribution. The 313 distribution information about G. macrophylla, 186 distribution information about G. straminea, 343 distribution information about G. dauricaand 131 distribution information about G. crasicaulis were collected though investigation and network sharing platform data . The ecology suitable distribution factors for production Gentianae Macrophyllae Radix was analyzed respectively by the software of ArcGIS and MaxEnt with 55 environmental factors. The result of MaxEnt prediction was very well (AUC was above 0.9). The results of predominant factors analysis showed that precipitation and altitude were all the major factors impacting the ecology suitable of Getiana Macrophylla Radix production. G. macrophylla ecology suitable region was mainly concentrated in south of Gansu, Shanxi, central of Shaanxi and east of Qinghai provinces. G. straminea ecology suitable region was mainly concentrated in southwest of Gansu, east of Qinghai, north and northwest of Sichuan, east of Xizang province. G. daurica ecology suitable region was mainly concentrated in south and southwest of Gansu, east of Qinghai, Shanxi and north of Shaanxi province. G. crasicaulis ecology suitable region was mainly concentrated in Sichuan and north of Yunnan, east of Xizang, south of Gansu and east of Qinghai province. The ecological suitability distribution result of Gentianae Macrophyllae Radix was consistent with each species actual distribution. The study could provide reference for the collection and protection of wild resources, meanwhile, provide the basis for the selection of cultivation area of Gentiana Macrophylla Radix. Copyright© by the Chinese Pharmaceutical Association.

Sun et al., Afr J Tradit Complement Altern Med. (2011) 8(3):224-229

African Journals Online (AJOL)

AJTCAM

Sun et al., Afr J Tradit Complement Altern Med. (2011) 8(3):224-229. 224. EFFECTS OF CHINESE MATERIA MEDICA-FUBAO DANGGUI JIAO ON EXPERIMENTAL. ENDOMETRIOSIS. Xing Sun*, Master; Lijue Chen, Master; Fanbo Zeng1,. Department of Pharmacy, Tongji Medical College, Huazhong. University of Science ...

COLONIAL AMERICAN LITERATURE: MARVELOUS WONDERS AND THE MEDIEVAL TRADITION IN LUSO-BRAZILIAN HISTORIOGRAPHICAL CHRONICLES COLONIAL American Literature: WONDERS maravilhoso e da tradição medieval NO LUSO-BRASILEIRA historiográfica CHRONICLES

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Pedro Fonseca

1996-01-01

Full Text Available Este artigo apresenta uma analise interpretativa de certos aspectos do imaginário literário medieval e sua influência na formação tropológica das crônicas do Novo Mundo. A abordagem examina algumas das motivações estéticas e mentais da tradição medieval no discurso historiográfico luso-brasileiro colonial, principalmente em relação a alguns relatos de descobrimentos e ocupação inicial de terras brasileiras na América. This article presents an interpretative analysis of certain aspects of the medieval literary imaginary and its influence in the tropological formation of the New World chronicles. The approach examines some of the aesthetic and mental motivations of the medieval tradition in the colonial Luso-Brazilian historiographical discourse, principally in regards to some accounts of discoveries and initial occupation of Brazilian lands in America.  

[Pharmaceutical research progress of rhynchophylla based on chemical stability].

Science.gov (United States)

Hao, Bo; Yang, Xiu-Juan; Feng, Yi; Hong, Yan-Long

2014-12-01

Rhynchophylla is a Chinese herb commonly used in clinical practice. It's also the primary herb of some famous Chinese herbal compound such as Tianma Gouteng decoction, and Lingyang Gouteng decoction. According the record from many previous materia medica literatures, rhynchophylla should be added later during decoction. Pharmaceutical research showed that rhynchophylla alkaloids were not stable. Which has resulted in many problems in the research and its application. For example, there was not a quantitative determination method in "Chinese Pharmacopoeia" of past and present versions, which seriously impacted its quality control and product application. Firstly, records from previous materia medica literatures and "Chinese Pharmacopoeia" were systematically sorted based on the chemical stability of rhynchophylla. Secondly, pharmaceutical research including chemical compositions and their stability, pharmacological effects, extraction process and quality analysis, was reviewed after reference of literatures published at home and abroad in recent decades. Positive reference and evidence for further research and development of rhynchophylla will be provided in the article.

THz reflectometric imaging of medieval wall paintings

DEFF Research Database (Denmark)

Dandolo, Corinna Ludovica Koch; Jepsen, Peter Uhd

2013-01-01

Terahertz time-domain reflectometry has been applied to the investigation of a medieval Danish wall painting. The technique has been able to detect the presence of carbonblack layer on the surface of the wall painting and a buried insertion characterized by high reflectivity values has been found...

The Vicissitudes of a Medieval Japanese Warrior

DEFF Research Database (Denmark)

Oxenbøll, Morten

2007-01-01

In standard accounts of medieval Japanese society, enormous stress is put on the conflicts between local landholders (zaichi ryôshu) and absentee proprietors. Fuelled by the debate on feudalism that divided scholars up until the early 1990s, these conflicts have widely been recognised as proof...

Episodes in the mathematics of medieval Islam

CERN Document Server

Berggren, J L

1986-01-01

From the reviews: The book is, in spite of the author's more modest claims, an introductory survey of main developments in those disciplines which were particularly important in Medieval Islamic mathematics...No knowledge of mathematics (or of the history of mathematics) beyond normal high-school level is presupposed, and everything required beyond that (be it Apollonian theory of conics or the definitions of celestial circles) is explained carefully and clearly. Scattered throughout the work are a number of lucid remarks on the character of Islamic mathematics or of mathematical work in general. The book will hence not only be an excellent textbook for the teaching of the history of mathematics but also for the liberal art aspect of mathematics teaching in general. - Jens Høyrup, Mathematical Reviews ...as a textbook, this work is highly commendable...It is definitely the product of a skillful mathematician who has collected over the years a reasonably large number of interesting problems from medieval Arab...

Uncovering the Secret: Medieval Women, Magic and the Other

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Ludwikowska Joanna

2015-01-01

Full Text Available For medieval audiences women occupied a specific, designated cultural area which, while they could freely form it according to their will and nature, was in fact imaginary and immaterial. Women in social, legal, and religious contexts were mostly counted among the receptive, inactive, and non-ruling groups. On both levels, there was a group of features universally defining all women: the strong, virtuous and independent model Aquinas lamented was replaced in real life by the sinful, carnal and weak stereotype, and the erotic, emotional, mysterious, and often wild type present predominantly in literature. Indeed, women were a source of scientific, theological, and cultural fascination because of their uncanny and complex nature, producing both fear and desire of the source and nature of the unattainable and inaccessible femininity. In social contexts, however, the enchantress seems to lose that veil of allure and, instead, is forced to re-define her identity by suppressing, denying, or losing her supernatural features. With the example of Saint Agnes from the South English Legendary Life of Saint Agnes, and Melior from Partonope of Blois (ca. 1450, the article will explore how medieval texts dealt with the complex and unruly female supernatural, and how its neutralization and subduing fitted into the moral, scientific, and cultural norms of medieval society.

„Incendula“ or „monedula“? An Enigmatic Bird Name in Medieval Latin-Written Sources

Czech Academy of Sciences Publication Activity Database

Šedinová, Hana

-, č. 74 (2016), s. 89-109 ISSN 1376-7453 Institutional support: RVO:67985955 Keywords : latin lexicography * ancient and medieval zoology * ancient and medieval zoology * latin names of birds * Bartholomaeus de Solencia dictus Claretus * Aristoteles * Aristoteles Latinus * Michael Scotus * Thomas of Cantimpré Subject RIV: AI - Linguistics OBOR OECD: Specific languages

La confrontación de Heidegger con san Agustín y la mística medieval: Nota crítica en torno a Estudios sobre mística medieval de Martin Heidegger

OpenAIRE

Santiesteban, Luis César

2007-01-01

El presente artículo da cuenta de algunos aspectos de la confrontación de Heidegger con san Agustín y la mística medieval, así como de la manera en que Heidegger, en su camino a Ser y tiempo, hace suya una parte del ideario del filósofo de Tagaste, y del modo en que se perfila y va tomando cuerpo su diálogo con la mística medieval y, a una con ello, su propia actitud religiosa. Para ello, se toma como base de la interpretación el texto de Heidegger Estudios sobre mística medieval. This art...

Comparison of antibacterial efficacy of intracanal medicaments in multiple visit pulpectomies in primary molars-an in vivo study

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Lele G

2010-03-01

Full Text Available Antibacterial efficacy of formocresol, 2% gluteraldehyde and iodine-potassium iodide was assessed by obtaining cultures at consecutive appointments in multiple visit pulpectomies in primary molars. Formocresol and 2% gluteraldehyde were more effective as intracanal medicaments and caused significant reduction in the counts of aerobic and anaerobic microorganisms, thereby supporting the need for placing intracanal medicaments with antibacterial properties, in multiple visit pulpectomies in primary molars.

Cities and Socialization of Libraries in Medieval Europe

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Dilek Bayır Toplu

2000-09-01

Full Text Available In this study, socialization of libraries in Medieval Europe has been examined by means of the growing of cities and movements of ideologies. Cities, as results of economic based changes, caused the apperance of merchantiles in produce and consumption flows. Cities, by selecting an area outside of feudal city walls, and by consisting new living habits which shows differances from village living habits took its place in Medieval Feudal Regime. While cities consist their conceits, conceits consists the specialisatians which identifies the city from the village. Technologic developments, innovations, the movements of different social classes, the changes in produce and consumption models, movements of ideologies; carried Medieval Europe to Enlighment Period after very long and difficult experiements. While the man in “Enlighment Period” ideologically based on rationalism and critical thinking; it realized knowledge as a product of rationalism. That realisation gave start to the socialisation of libraries and books and books which includes the “knowledge” stating with the innovation of press, the gobalization of books and the movements in cities gave speed to the interaction between cultures and effected the extansi-on of knowledge in a positive way. While knowledge was socialized by means of the opportunities of cities, libraries became space which knowledge can easily reachable by society. Cities arosed in Middle ageesand by effecting social structures, they became an indirect effect for reaching of libraries to society and moneyfree service.

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African Journals Online (AJOL)

cadewumi

measurement of the Institute of Materia Medica of Chinese Academy of Medical Sciences, Radix ranunculus ternati contains 16% of sugar, 1.2% of oil, and very little plant alkaloids (Yang et al., 1998). Japanese scholars have separated and identified monosaccharide constituents such as glucose, arabinose and galactose ...

Ancient and medieval Iberia seen through glass: An archaeometric perspective

International Nuclear Information System (INIS)

Juan Ares, J. de; Nadine Schibille, N.

2017-01-01

The study of ancient and medieval glasses has identified distinct compositional groups as a result of the chemical characteristics of the raw materials used for its production. Archaeometric analysis can determine the provenance of the glass, and has demonstrated a large-scale production and commercialisation of raw glass throughout the Mediterranean during the ancient and medieval periods. Secondary workshops on the Iberian Peninsula imported raw glass from the Near East for the better part of the first millennium CE, following a similar pattern observed elsewhere in the Mediterranean region. However, there are some indications that point to a local production of glass and that deserve further investigation. In the ninth century, natron glass was replaced in al-Ándalus by plant ash and lead-rich glass that may represent a local production. Little is known about the production or use of glass in the Christian parts of the peninsula during this period. The increasing volume of analytical data on Spanish glass demonstrates the potential of an archaeometric approach to shed light not only on the production and trade of glass on the Iberian Peninsula but also on the ancient and medieval economy more generally. [es

Paradise, pleasure and desire: Edenic delight in some late-medieval dramatic fragments

OpenAIRE

James, Sarah

2017-01-01

This paper explores the biblical Paradise and its relationship with the concept of delight or pleasure. In the first section it discusses the changing descriptions and interpretations of Paradise, from the biblical text to later medieval works; it goes on to explore the Augustinian and Thomist philosophies of pleasure and delight. Finally it brings together three late-medieval dramatic texts, all of which share an interest in Paradise, and explores the ways in which these texts utilise the co...

The direct cytotoxic effects of medicaments used in endodontic regeneration on human dental pulp cells.

Science.gov (United States)

Labban, Nawaf; Yassen, Ghaeth H; Windsor, L Jack; Platt, Jeffrey A

2014-12-01

The purpose of this in vitro study was to evaluate the effects of intracanal medicaments commonly used in endodontic regeneration on the survival of human dental pulp cells (DPCs). DPCs were cultured and exposed to either no medicament treatment or low concentrations (0.3-5 mg ml(-1) ) of calcium hydroxide [Ca(OH)2 ], triple antibiotic paste (TAP), or double antibiotic paste (DAP) for 3 days. After that, toxicity to the DPCs was determined by lactate dehydrogenase activity assays (LDH) and cell proliferation was measured by colorimetric assays (WST-1). Two-way anova followed by Fisher's protected least significant differences was used for statistical analyses (α = 0.05). The group-by-concentration interactions were significant for the LDH and WST-1 assays (P medicaments tested in this study were not cytotoxic in cultured cells. However, these concentrations are much lower than the concentrations that have been advocated in endodontic regeneration. Furthermore, the negative effects of TAP on DPCs were detected at lower concentrations by using the WST-1 assays than by measuring the LDH release. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Salpeterzuurdestructie en ICP-MS analyse van biotisch materiaal en voeding

NARCIS (Netherlands)

Velde-Koerts T van der; LAC

2000-01-01

Voor de bepaling van elementen in voeding en biotisch materiaal werd een analytische methode ontwikkeld, bestaande uit een salpeterzuurdestructie en een ICP-MS-analyse. De destructie werd geoptimaliseerd op basis van de salpeterzuurconcentratie en de destructietijd. De ICP-MS-analyse werd

Funcionamento intelectual em pacientes pediátricos com epilepsia: comparação de crianças controladas com medicação, não controladas com medicação e controladas com cirurgia

OpenAIRE

Souza-Oliveira,Cecília; Escosi-Rosset,Sara; Funayama,Sandra S.; Terra,Vera C.; Machado,Hélio R.; Sakamoto,Américo C.

2010-01-01

OBJETIVO: Comparar o quociente intelectual (QI) em três grupos de crianças com epilepsia: 1) controlados com medicação, 2) não controlados com medicação e 3) controlados com cirurgia. MÉTODOS: Noventa e oito pacientes pediátricos, com idades entre 6 e 12 anos, foram selecionados de dezembro de 2007 a julho de 2008. A Escala de Inteligência Wechsler para Crianças - terceira edição (WISC-III) foi utilizada para a avaliação neuropsicológica dos pacientes. Os resultados foram relacionados com a s...

Effect of four different intracanal medicaments on the apical seal of the root canal system: a dye extraction study.

Science.gov (United States)

Tandan, Monika; Hegde, Mithra N; Hegde, Priyadarshini

2014-01-01

The aim was to determine the effect of four different intracanal medicaments on the apical seal of the root canal system in vitro. Fifty freshly extracted intact human permanent maxillary central incisors were collected, stored and disinfected. The root canals were prepared to a master apical size of number 50 using step back technique. Depending upon the intracanal medicament used, the teeth were divided randomly into five groups of 10 teeth each including one control group and four experimental groups. Group A: No intracanal medicament. Group B: Calcium hydroxide powder mixed with distilled water. Group C: Calcium hydroxide gutta percha points (calcium hydroxide points). Group D: 1% chlorhexidine gel (hexigel). Group E: Chlorhexidine gutta percha points (Roeko Activ Points). The medication was left in canals for 14 days. Following removal of the intracanal medicament, all the groups were obturated with lateral compaction technique. The apical leakage was then evaluated using dye extraction method with the help of a spectrophotometer. RESULTS were statistically analyzed using Kruskal-Wallis and Mann-Whitney U-test, which showed statistically significant difference among the five groups tested. It can be concluded from this study that the control group showed least amount of leakage, whereas the 1% chlorhexidine gel group showed maximum amount of leakage. Apical leakage was observed with all the experimental groups with little variations in between them. Under the parameters of this study, it can be concluded that use of intracanal medicaments during endodontic treatment has a definite impact on the apical seal of the root canal system.

Los animales en el mundo medieval cristiano-occidental : actitud y mentalidad

Directory of Open Access Journals (Sweden)

María Dolores Carmen Morales Muñiz

1998-01-01

Full Text Available El presente trabajo analiza el peso que los animales tuvieron en la sociedad medieval y especialmente en la mentalidad del hombre. Se subraya la importancia que el uso material de los animales tuvo a la hora de conformar esa actitud. En la segunda parte del trabajo se profundiza en manifestaciones como la simbología o la magia en donde los animales jugaron un papel principal. Un último punto del trabajo comenta la hipótesis de J. Salisbury sobre el descubrimiento, a partir del siglo xii, del animal interior presente en los hombres.The present paper reviews the role played by animals in medieval society and mentality. In particular we stress the importance which the material use of each species had in determining specific roles. The second part of the work deals with symbolic and magical connotations, fields in which animáis played a most prominent role throughout medieval times. One final aspect comments on J. Salisbury's hypothesis of «the beast within man» which seems to date back to the tweifth century.

Publications | Page 581 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Results 5801 - 5810 of 6374 ... Mn access to its toxic target, the brain, is a complex phenomenon subject to physiological and physiopathological processes; in which, among others, the route... Report on workshops for the development of Materia Medica Regulations for Traditional and Alternative Medicine Act No. 23 of 2002 ...

Simultaneous Determination of Flavonols and Terpene Lactones in ...

African Journals Online (AJOL)

Lactones in Beagle Dog Plasma by Ultra-Performance ... School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, ... Matrix effect derived from QC samples was in the range of 85.09 – 113.14 %. ..... with the suitable weighting factor of 1/x. .... pharmacokinetic studies of G. biloba and its.

Immunity ratione materiae of foreign state officials before Rwandan ...

African Journals Online (AJOL)

The article seeks to determine when, as a matter of international law, foreign state officials should be granted immunity ratione materiae when they are sued in civil and criminal proceedings in Rwanda. It also investigates the questions as to whether this immunity can be waived by the state on behalf of which the official ...

Diabetes and related remedies in medieval Persian medicine

Science.gov (United States)

Zarshenas, Mohammad M.; Khademian, Sedigheh; Moein, Mahmoodreza

2014-01-01

Diabetes Mellitus is a common metabolic disorder presenting increased amounts of serum glucose and will cover 5.4% of population by year 2025. Accordingly, this review was performed to gather and discuss the stand points on diagnosis, pathophysiology, non-pharmacological therapy and drug management of diabetes this disorder as described in medieval Persian medicine. To this, reports on diabetes were collected and analyzed from selected medical and pharmaceutical textbooks of Traditional Persian Medicine. A search on databases as Pubmed, Sciencedirect, Scopus and Google scholar was also performed to reconfirm the Anti diabetic activities of reported herbs. The term, Ziabites, was used to describe what is now spoken as diabetes. It was reported that Ziabites, is highly associated with kidney function. Etiologically, Ziabites was characterized as kidney hot or cold dystemperament as well as diffusion of fluid from other organs such as liver and intestines into the kidneys. This disorder was categorized into main types as hot (Ziabites-e-har) and cold (Ziabites-e-barid) as well as sweet urine (Bole-e-shirin). Most medieval cite signs of Ziabites were remarked as unusual and excessive thirst, frequent urination and polydipsia. On the management, life style modification and observing the essential rules of prevention in Persian medicine as well as herbal therapy and special simple manipulations were recommended. Current investigation was done to clarify the knowledge of medieval scientists on diabetes and related interventions. Reported remedies which are based on centuries of experience might be of beneficial for- further studies to the management of diabetes. PMID:24741508

Bohemian so-called surgical early medieval knives

Czech Academy of Sciences Publication Activity Database

Hošek, Jiří; Profantová, Naďa; Šilhová, Alena; Ottenwelter, Estelle

2007-01-01

Roč. 2007, č. 1 (2007), s. 932-937 ISSN 1335-1532. [Metallography 2007. Stará Lesná, 02.05.2007-04.05.2007] R&D Projects: GA AV ČR IAA800020603; GA ČR GA404/05/0232 Institutional research plan: CEZ:AV0Z80020508 Keywords : knife * medieval * archaeometallurgy Subject RIV: AC - Archeology, Anthropology, Ethnology

[Women, bodies, and Hebrew medieval medical literature].

Science.gov (United States)

Navas, Carmen Caballero

2008-01-01

This essay explores different views on the female body articulated within Hebrew medieval texts on women's health care. It also investigates whether texts also integrate women's own perceptions of their bodies, and of their needs and care. I have analysed how this genre of Hebrew literature understood two key issues in the construction of sexed bodies: menstruation and cosmetics.

SharedCanvas: A Collaborative Model for Medieval Manuscript Layout Dissemination

Energy Technology Data Exchange (ETDEWEB)

Sanderson, Robert D. [Los Alamos National Laboratory; Albritton, Benjamin [Stanford University; Schwemmer, Rafael [e-codices; Van De Sompel, Herbert [Los Alamos National Laboratory

2011-01-01

In this paper we present a model based on the principles of Linked Data that can be used to describe the interrelationships of images, texts and other resources to facilitate the interoperability of repositories of medieval manuscripts or other culturally important handwritten documents. The model is designed from a set of requirements derived from the real world use cases of some of the largest digitized medieval content holders, and instantiations of the model are intended as the input to collection-independent page turning and scholarly presentation interfaces. A canvas painting paradigm, such as in PDF and SVG, was selected based on the lack of a one to one correlation between image and page, and to fulfill complex requirements such as when the full text of a page is known, but only fragments of the physical object remain. The model is implemented using technologies such as OAI-ORE Aggregations and OAC Annotations, as the fundamental building blocks of emerging Linked Digital Libraries. The model and implementation are evaluated through prototypes of both content providing and consuming applications. Although the system was designed from requirements drawn from the medieval manuscript domain, it is applicable to any layout-oriented presentation of images of text.

Human Parasites in Medieval Europe: Lifestyle, Sanitation and Medical Treatment.

Science.gov (United States)

Mitchell, Piers D

2015-01-01

Parasites have been infecting humans throughout our evolution. However, not all people suffered with the same species or to the same intensity throughout this time. Our changing way of life has altered the suitability of humans to infection by each type of parasite. This analysis focuses upon the evidence for parasites from archaeological excavations at medieval sites across Europe. Comparison between the patterns of infection in the medieval period allows us to see how changes in sanitation, herding animals, growing and fertilizing crops, the fishing industry, food preparation and migration all affected human susceptibility to different parasites. We go on to explore how ectoparasites may have spread infectious bacterial diseases, and also consider what medieval medical practitioners thought of parasites and how they tried to treat them. While modern research has shown the use of a toilet decreases the risk of contracting certain intestinal parasites, the evidence for past societies presented here suggests that the invention of latrines had no observable beneficial effects upon intestinal health. This may be because toilets were not sufficiently ubiquitous until the last century, or that the use of fresh human faeces for manuring crops still ensured those parasite species were easily able to reinfect the population. Copyright © 2015 Elsevier Ltd. All rights reserved.

Carabelli's trait in contemporary Slovenes and inhabitants of a medieval settlement (Sredisce by the Drava River).

Science.gov (United States)

Stamfelj, Iztok; Stefancić, Marija; Gaspersic, Dominik; Cvetko, Erika

2006-06-01

The objectives of this study were to determine the total frequency, expression and asymmetry of Carabelli's trait in permanent dentitions of contemporary Slovenes and a medieval skeletal population from northeastern Slovenia. A total of 254 dental casts from contemporary Slovene children were examined. The population of a medieval settlement (10th-15th centuries), was represented by 94 skeletons. A modification of the method of Alvesalo and associates was used to classify Carabelli's trait on a five-grade scale. The trait was expressed on the upper first molars of 79.7% of the contemporary subjects and 75.8% of the medieval sample. Positive expressions of the trait were found in 10.1% of the contemporary subjects and 15.2% of the medieval sample. While the observed total frequency of the trait in both samples is characteristic of Europeans, the rates of positive expressions are surprisingly low but consistent with data from a recently published worldwide literature survey. Both populations showed a low rate of left-right fluctuating asymmetry of the trait. This finding might reflect a pronounced ability of individuals in the medieval population to buffer unfavourable influences from the environment and a relatively low level of environmental stress in the contemporary population.

Investigation of original bricks from Ventspils castle for the purpose of restorations of medieval brick masonry

International Nuclear Information System (INIS)

Bajare, D.; Shvinka, V.

2000-01-01

This paper mainly tries to characterize Middle Age brick taken from Ventspils Castle (13-17th century). To this aim, the following techniques were applied: visual inspection, X-ray diffraction, mercury porosimetry, physical laboratory tests (water absorption, density, open porosity, saturation coefficient, Mage's index) and chemical analysis. The medieval bricks are still in good condition, any visible damages were not recognized in the course of visual inspection. According to the results of chemical analysis, three types of bricks made from different clays in different centuries were used. According to X-ray diffraction analysis data no one type of medieval bricks contains illite. So sintering temperature of the medieval bricks studied was higher than 900 deg C. The secondary calcite was formed in the structure of bricks from lime mortars under influence of water migration during several centuries. All medieval bricks studied are porous - open porosity of them amounts to 26-30 %. 14-15th century bricks have inclusions of chamotte additive, which makes the bricks less durable to soluble salts and frost, and of organic additive, that imparts the higher porosity. Mage's index for all medieval is less than 0.55, but saturation coefficient is close to 0,78 and it means that these bricks are not enough durable to soluble salts and frost

Purposing Division Strategy for Pharmaceutical Producer Dexa Medica in the Demanding Market

Science.gov (United States)

Setiawati, Cut Irna; Wahyono, Agatha Christy

2017-01-01

This research aims to purpose the division strategy for a pharmaceutical producer in Kalimantan area, named Dexa Medica Samarinda. Currently, this firm is facing a competitive market condition and evolving a decline position in the market. This research uses qualitative research method by organising intensive interview to important informants so…

Multi-Ethnicity and Material Exchangesin Late Medieval Tallinn

DEFF Research Database (Denmark)

Naum, Magdalena

2014-01-01

his article examines the cultural and social dynamics of a multi-ethnic medieval town. Taking the lower town of Tallinn as a case study, this paper identifies the major urban ethnic groups living in the town and discusses their co-existence, self-definition, and processes of categorization...

[Medicaments and oral healthcare 4. Pharmacotherapy in (frail and care dependent) older people].

NARCIS (Netherlands)

Baat, C. de; Putten, G.J. van der; Visser, A.; Vissink, A.

2017-01-01

Polypharmacy is the consequence of multimorbidity. Both phenomena may cause functional limitations and/or frailty and/or care dependency in older people. In the human body, a medicament undergoes at least 3 important actions: absorption, distribution and elimination. These actions may proceed

Diet and mobility in Early Medieval Bavaria: a study of carbon and nitrogen stable isotopes.

Science.gov (United States)

Hakenbeck, Susanne; McManus, Ellen; Geisler, Hans; Grupe, Gisela; O'Connell, Tamsin

2010-10-01

This study investigates patterns of mobility in Early Medieval Bavaria through a combined study of diet and associated burial practice. Carbon and nitrogen isotope ratios were analyzed in human bone samples from the Late Roman cemetery of Klettham and from the Early Medieval cemeteries of Altenerding and Straubing-Bajuwarenstrasse. For dietary comparison, samples of faunal bone from one Late Roman and three Early Medieval settlement sites were also analyzed. The results indicate that the average diet was in keeping with a landlocked environment and fairly limited availability of freshwater or marine resources. The diet appears not to have changed significantly from the Late Roman to the Early Medieval period. However, in the population of Altenerding, there were significant differences in the diet of men and women, supporting a hypothesis of greater mobility among women. Furthermore, the isotopic evidence from dietary outliers is supported by "foreign" grave goods and practices, such as artificial skull modification. These results reveal the potential of carbon and nitrogen isotope analysis for questions regarding migration and mobility. © 2010 Wiley-Liss, Inc.

Some more earthquakes from medieval Kashmir

Science.gov (United States)

Ahmad, Bashir; Shafi, Muzamil

2014-07-01

Kashmir has the peculiarity of having written history of almost 5,000 years. However, the description of earthquakes in the archival contents is patchy prior to 1500 a.d. Moreover, recent search shows that there exist certain time gaps in the catalogs presently in use especially at medieval level (1128-1586 a.d.). The presence of different ruling elites in association with socioeconomic and political conditions has in many ways confused the historical context of the medieval sources. However, by a meticulous review of the Sanskrit sources (between the twelfth and sixteenth century), it has been possible to identify unspecified but fair number (eight seismic events) of earthquakes that do not exist in published catalogs of Kashmir or whose dates are very difficult to establish. Moreover, historical sources reveal that except for events which occurred during Sultan Skinder's rule (1389-1413) and during the reign of King Zain-ul-Abidin (1420-1470), all the rediscovered seismic events went into oblivion, due mainly to the fact that the sources available dedicated their interests to the military events, which often tended to overshadow/superimpose over and even concealed natural events like earthquakes, resulting in fragmentary accounts and rendering them of little value for macroseismic intensity evaluation necessary for more efficient seismic hazard assessment.

Making medieval art modern

Directory of Open Access Journals (Sweden)

Elizabeth den Hartog

2015-12-01

Full Text Available Janet T. Marquardt’s book ‘Zodiaque. Making medieval art modern’ discusses the historical context, history and impact of the Zodiaque publications issued by the monks from the abbey of Ste-Marie de la Pierre-qui-Vire in Burgundy between 1951 and 2001 and links the striking photogravures, the core business of these books, to the modern movement. Although Marquardt’s view that the Zodiaque series made a great impact on the study of Romanesque sculpture is somewhat overrated, her claim that the photogravures should be seen as avant-garde works of art and the books as a “museum without walls” is entirely convincing.

Russian Medieval Military Architecture

Directory of Open Access Journals (Sweden)

Rappoport, Pavel

1969-12-01

Full Text Available In Russia defensive works were not less important than in Western Europe. Russian chronicles are full of reports of the building of towns, of their siege and defence. In Ancient Russian the word town meant not a town in the modern sense, but only a fortified settlement as distinct from an unfortified one. Thus the concept town applied to medieval towns proper and to citadels, feudal castles and even fortified villages. Every population centre with a wall round it was called a town. Moreover, until the 17th century this word was frequently applied to mean the fortifications themselves.

Duration and severity of Medieval drought in the Lake Tahoe Basin

Science.gov (United States)

Kleppe, J.A.; Brothers, D.S.; Kent, G.M.; Biondi, F.; Jensen, S.; Driscoll, N.W.

2011-01-01

Droughts in the western U.S. in the past 200 years are small compared to several megadroughts that occurred during Medieval times. We reconstruct duration and magnitude of extreme droughts in the northern Sierra Nevada from hydroclimatic conditions in Fallen Leaf Lake, California. Stands of submerged trees rooted in situ below the lake surface were imaged with sidescan sonar and radiocarbon analysis yields an age estimate of ∼1250 AD. Tree-ring records and submerged paleoshoreline geomorphology suggest a Medieval low-stand of Fallen Leaf Lake lasted more than 220 years. Over eighty more trees were found lying on the lake floor at various elevations above the paleoshoreline. Water-balance calculations suggest annual precipitation was less than 60% normal from late 10th century to early 13th century AD. Hence, the lake’s shoreline dropped 40–60 m below its modern elevation. Stands of pre-Medieval trees in this lake and in Lake Tahoe suggest the region experienced severe drought at least every 650–1150 years during the mid- and late-Holocene. These observations quantify paleo-precipitation and recurrence of prolonged drought in the northern Sierra Nevada.

Evolution of Management Thought in the Medieval Times.

Science.gov (United States)

Sharma, C. L.

The medieval times witnessed progress toward the growth of larger and more complex organizations and the application of increasingly sophisticated management techniques. Feudalism contributed the concept of decentralization. The concepts evolved by the Catholic Church can scarcely be improved on and are very much pertinent to the management of…

An Evidence-Based Review on Medicinal Value of Clays in Traditional Persian Medicine.

Science.gov (United States)

Hosseinkhani, Ayda; Montaseri, Hashem; Hosamo, Ammar; Zarshenas, Mohammad Mehdi

2017-01-01

The use of earths and clays for medical purposes dates back to antiquity. In recent years, there has been an increasing interest in researches on traditional remedies in the hope of discovering new drug. Iran is an ancient country with a medical backbone acquired from the experiences of ancient Persian scholars, who had made a great contribution to the development of the medical sciences. Many medical and pharmaceutical books by early Persian scientists still exist and may have the potential of leading researchers to new drug discoveries. Owing to the emergence of new and antimicrobial-resistant infections, present-day medicine has recently begun focusing on medicinal earths and clays especially as mineral antimicrobials. The current study is, therefore, aimed at gathering information regarding medicinal clays in traditional Persian medicine (TPM). Five main Persian materia medica with the key word 'tin' (clay) and current databases such as PubMed, Scopus, ScienceDirect, and Google Scholar were searched by key words 'white, green, red, maroon, violet, black, grey and pink clays' and 'pharmacological effects'. Twenty three clays were found in Persian manuscripts. Although their mineralogical compositions are unknown, different pharmacological properties have been attributed to these mineral medicaments. Clay's properties were widely used in medieval times for the treatment of infections to poisoning. They were also used in compound formulations, possibly for their pharmaceutical formulation modifying effects. Modern scientific proofs have also been found in many of the medicinal clays reported in Persian manuscripts. Although many of the reported clays are still unknown, their characterization may lead to new medicinal developments. Novel analytical methods available today make it possible to elucidate the chemical compositions of these minerals as parameters responsible for their medicinal effects. Copyright© Bentham Science Publishers; For any queries, please

Genome-wide comparison of medieval and modern Mycobacterium leprae.

Science.gov (United States)

Schuenemann, Verena J; Singh, Pushpendra; Mendum, Thomas A; Krause-Kyora, Ben; Jäger, Günter; Bos, Kirsten I; Herbig, Alexander; Economou, Christos; Benjak, Andrej; Busso, Philippe; Nebel, Almut; Boldsen, Jesper L; Kjellström, Anna; Wu, Huihai; Stewart, Graham R; Taylor, G Michael; Bauer, Peter; Lee, Oona Y-C; Wu, Houdini H T; Minnikin, David E; Besra, Gurdyal S; Tucker, Katie; Roffey, Simon; Sow, Samba O; Cole, Stewart T; Nieselt, Kay; Krause, Johannes

2013-07-12

Leprosy was endemic in Europe until the Middle Ages. Using DNA array capture, we have obtained genome sequences of Mycobacterium leprae from skeletons of five medieval leprosy cases from the United Kingdom, Sweden, and Denmark. In one case, the DNA was so well preserved that full de novo assembly of the ancient bacterial genome could be achieved through shotgun sequencing alone. The ancient M. leprae sequences were compared with those of 11 modern strains, representing diverse genotypes and geographic origins. The comparisons revealed remarkable genomic conservation during the past 1000 years, a European origin for leprosy in the Americas, and the presence of an M. leprae genotype in medieval Europe now commonly associated with the Middle East. The exceptional preservation of M. leprae biomarkers, both DNA and mycolic acids, in ancient skeletons has major implications for palaeomicrobiology and human pathogen evolution.

"La Chanson de Roland" in the Elementary School Classroom: A Case for Medieval Literature and Young Language Students.

Science.gov (United States)

Petry, Karla L.

1981-01-01

Describes successful experiment in teaching of medieval literature to elementary French language classes in the Cincinnati public schools. Purpose was to strengthen linguistic awareness and expand social studies unit on medieval France. (BK)

THE ORIGIN OF THE CONCEPT OF NEUROPATHIC PAIN IN EARLY MEDIEVAL PERSIA (9TH-12TH CENTURY CE).

Science.gov (United States)

Heydari, Mojtaba; Shams, Mesbah; Hashempur, Mohammad Hashem; Zargaran, Arman; Dalfardi, Behnam; Borhani-Haghighi, Afshin

2015-01-01

Neuropathic pain is supposed to be a post-renaissance described medical entity. Although it is often believed that John Fothergill (1712-1780) provided the first description of this condition in 1773, a review of the medieval Persian medical writings will show the fact that neuropathic pain was a medieval-originated concept. "Auojae Asab" [Nerve-originated Pain] was used as a medical term in medieval Persian medical literature for pain syndromes which etiologically originated from nerves. Physicians like Rhazes (d. 925 CE), Haly Abbas (d. 982 CE), Avicenna (d. 1037 CE), and Jorjani (d. 1137 CE) have discussed multiple aspects of nerve-originated pain including its classification, etiology, differentiating characteristics, different qualities, and pharmacologic and non-pharmacologic treatments. Recognizing medieval scholars' views on nerve-originated pain can lighten old historical origins of this concept.

William Burchell's medical challenges: A 19th-century natural ...

African Journals Online (AJOL)

One of the most riveting is his successful care of an assistant whose left hand was severely mutilated when a firearm exploded in his hands. Burchell was probably the first person to include the materia medica of the Khoi in an essentially European approach to the non-surgical management of such a serious condition.

The effective method for investigation meridian tropism theory in rats ...

African Journals Online (AJOL)

... was in accordance with the MT record of Xiheliu and confirmed that tamarixetin and kaempferide was the material bases of it on MT. This is the first report for the illumination of material basis and the mechanism of Xiheliu on MT by analysis the record of Xiheliu in Compendium of Materia Medica and experimental study.

IBARAKI materials design diffractometer (iMATERIA)-Versatile neutron diffractometer at J-PARC

International Nuclear Information System (INIS)

Ishigaki, T.; Hoshikawa, A.; Yonemura, M.; Morishima, T.; Kamiyama, T.; Oishi, R.; Aizawa, K.; Sakuma, T.; Tomota, Y.; Arai, M.; Hayashi, M.; Ebata, K.; Takano, Y.; Komatsuzaki, K.; Asano, H.; Takano, Y.; Kasao, T.

2009-01-01

Ibaraki prefecture, the local government of the area for J-PARC site, was decided to build a versatile neutron diffractometer (IBARAKI Materials Design Diffractometer, iMATERIA) to promote an industrial application for neutron beam in J-PARC. iMATERIA is planned to be a high throughput diffractometer so that materials engineers and scientists can use it like the chemical analytical instruments in their materials development process. It covers in d range 0.18< d (A)<5 with Δd/d=0.16% at high resolution bank, and covers 5< d (A)<800 with gradually changing resolution at three detector bank (90 deg., low angle and small angle). Typical measuring time to obtain a 'Rietveld-quality' data is several minutes with the sample size of laboratory X-ray diffractometer. To promote industrial application, a utilization system for this diffractometer is required. We will establish a support system for both academic and industrial users who are willing to use neutron but have not been familiar with neutron diffraction. The analysis software is also very important for powder diffraction, we will also prepare a software package consisting of combination of several powder-diffraction software, structural databases and visualization. The construction of iMATERIA will be completed in the end of April 2008, as one of day-one instruments for J-PARC.

The Gendered Nose and its Lack: "Medieval" Nose-Cutting and its Modern Manifestations.

Science.gov (United States)

Skinner, Patricia

2014-01-01

Time magazine's cover photograph in August 2010 of a noseless Afghan woman beside the emotive strap line, "What happens if we leave Afghanistan," fuelled debate about the "medieval" practices of the Taliban, whose local commander had instructed her husband to take her nose and ears. Press reports attributed the violence to the Pashtun tradition that a dishonored husband "lost his nose." This equation of nose-cutting with tradition begs questions not only about the Orientalist lens of the western press when viewing Afghanistan, but also about the assumption that the word "medieval" can function as a label for such practices. A study of medieval nose-cutting suggests that its identification as an "eastern" practice should be challenged. Rather clearer is its connection with patriarchal values of authority and honor: the victims of such punishment have not always been women, but this is nevertheless a gendered punishment of the powerless by the powerful.

Materiality of Body: The Material Practices of Life and Death in Medieval Britain

Directory of Open Access Journals (Sweden)

Mabast A. Muhammad Amin

2017-09-01

Full Text Available The aim of this paper is to investigate the ways people understood their body during the medieval period in Britain. I bring together the multiple different ways in which the body was treated in death, I focus on the role and power of grave goods and evidence found in dead bodies for plasticity in life to embrace the complexity of the medieval body, I examine the cultural practice of nutrition and environment affected the bodily mold. Another point I take into consideration is the practice of dietary through differentiation between male and female body in which we explore how medieval people socially and culturally constructed body based on their notion and understanding of gender identity. In addition, religion had a great influence on people’s understanding to deal with dead bodies and I concentrate on how bodily resurrection impacted on people’s preparation for the Day of Judgment by placing the goods in burials.

Non-scientific classification of Chinese herbal medicine as dietary supplement.

Science.gov (United States)

Bao, Kexin

2017-03-01

This article focuses the category status of Chinese herbal medicine in the United States where it has been mistakenly classifified as a dietary supplement. According to Yellow Emperor Canon of Internal Medicine (Huang Di Nei Jing), clinical treatment in broad sense is to apply certain poisonous medicines to fight against pathogeneses, by which all medicines have certain toxicity and side effect. From ancient times to modern society, all, or at least most, practitioners have used herbal medicine to treat patients' medical conditions. The educational curriculums in Chinese medicine (CM) comprise the courses of herbal medicine (herbology) and herbal formulae. The objective of these courses is to teach students to use herbal medicine or formulae to treat disease as materia medica. In contrast, dietary supplements are preparations intended to provide nutrients that are missing or are not consumed in suffificient quantity in a person's diet. In contrast, Chinese herbs can be toxic, which have been proven through laboratory research. Both clinical practice and research have demonstrated that Chinese herbal medicine is a special type of natural materia medica, not a dietary supplement.

Limitations imposed by wearing armour on Medieval soldiers' locomotor performance.

Science.gov (United States)

Askew, Graham N; Formenti, Federico; Minetti, Alberto E

2012-02-22

In Medieval Europe, soldiers wore steel plate armour for protection during warfare. Armour design reflected a trade-off between protection and mobility it offered the wearer. By the fifteenth century, a typical suit of field armour weighed between 30 and 50 kg and was distributed over the entire body. How much wearing armour affected Medieval soldiers' locomotor energetics and biomechanics is unknown. We investigated the mechanics and the energetic cost of locomotion in armour, and determined the effects on physical performance. We found that the net cost of locomotion (C(met)) during armoured walking and running is much more energetically expensive than unloaded locomotion. C(met) for locomotion in armour was 2.1-2.3 times higher for walking, and 1.9 times higher for running when compared with C(met) for unloaded locomotion at the same speed. An important component of the increased energy use results from the extra force that must be generated to support the additional mass. However, the energetic cost of locomotion in armour was also much higher than equivalent trunk loading. This additional cost is mostly explained by the increased energy required to swing the limbs and impaired breathing. Our findings can predict age-associated decline in Medieval soldiers' physical performance, and have potential implications in understanding the outcomes of past European military battles.

Medieval Day at Reynolds: An Interdisciplinary Learning Event

Science.gov (United States)

Morrison, Nancy S.

2012-01-01

Medieval Day at Reynolds turned a typical Friday class day into an interdisciplinary learning event, which joined faculty and students into a community of learners. From classrooms issued tales of Viking and Mongol conquests, religious crusaders, deadly plague, and majestic cathedrals and art, all told by costumed faculty members with expertise in…

Biblioteca Medica in Trient und die Initiative „Es gibt ein Kind im Krankenhaus … Schenk ihm ein Buch!“

Directory of Open Access Journals (Sweden)

Trevisan, Sergio

2016-12-01

Full Text Available In the autumn of 2011 the Biblioteca Medica of the hospital in Trento (Italy received four thousand children’s and youth books. They were donated during a philanthropic action by customers of a bookstore chain. Together with volunteers of the ABIO Foundation, the Biblioteca Medica has partly donated these media to the children in the hospital and, with the rest of the books, organized some bookshelf at the pediatric wards.

Migration to the medieval Middle East with the crusades.

Science.gov (United States)

Mitchell, Piers D; Millard, Andrew R

2009-11-01

During the 12th and 13th centuries thousands of people moved from Europe to the Middle East to fight, undertake pilgrimage, or settle and make a new life. The aim of this research is to investigate two populations from the Crusader kingdom of Jerusalem, by determining who was born in Europe and who came from the Middle East. Oxygen and strontium stable isotope analyses were conducted on the enamel of teeth from skeletal remains excavated from Crusader contexts. Twenty individuals from the coastal city of Caesarea (10 high status and 10 low status), and two local Near Eastern Christian farmers from the village of Parvum Gerinum (Tel Jezreel) were analyzed as a control sample. Results were compared with known geographic values for oxygen and strontium isotopes. The population of the city of Caesarea appears to have been dominated by European-born individuals (probably 19/20, but at least 13/20), with few locals. This was surprising as a much higher proportion of locals were expected. Both controls from the farming village of Parvum Gerinum had spent their childhood in the area of the village, which matches our understanding of limited mobility among poor Medieval farmers. This is the first time that stable isotope analysis has been applied to the study of the migration of peoples between Medieval Europe and the Middle East at the time of the crusades. In view of these findings, we must now rethink past estimations of population social structure in Levantine coastal Medieval cities during the Crusader period.

The medieval feminine personage in the romance O guarani

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Afrânio Gurgel Lucena

2011-06-01

Full Text Available We objectify to present a intertextual analysis of the literary text that contemplates a process of mythical constitution of the personages of the romance the Guarani (1857 of the writer Jose de Alencar. Focamos the analysis on the Cecília young for where we discover its “static” adaptation as medieval myth in the Brazilian romantic romance. The unconditional, protective and servile love of the Peri indian (One arquétipo of the medieval knight. conditions the construction of the loved one, therefore under the medieval myth of the gracious love, a personage is formed in function of the other, is opposing destinations that search the balance in the love. Exactly being something distant and inaccessible, as they present the trovadorescas Cantigas of love. In the theoretical recital, we have: MOISÉS (2004 - 2005 characterizing the mythos and the definitions of the plain and round personages; a platonic reference to the servile love in the Slap-up meal; Spalding (1973, Brunel (1988 for the dicionarizações concerning the thematic one and of the critical one; in the literary theory, Brunel, Pichois and Rousseau (1995, p.115: the myth, “a narrative set consecrated by the tradition”; in Samuel (2000, the mythical literariedade in the formation of a people; Bosi (1994, information on the indianismo and Coutinho (1988, gênese of our literariedade and the romantic romance. Thus, our work presents a result to the literary study: the thematic influence of the Average Age and its mythical love (gracious and servile in the composition of the indianista romance.

Postmortem Inventories in Medieval Valencia. A Source for the Study of Household Consumption and Living Standards

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Luis Almenar Fernández

2017-12-01

Full Text Available Basic questions about the nature of postmortem inventories in late medieval Valencia have rarely been asked. What distinguished them from other lists of goods and what was their legal basis? Why were inventories made? Which goods were listed and which ones omitted? How many inventories are preserved today? Which sectors of medieval society requested them? The answers that this paper provides clearly show the potential of a serial and quantitative usage of the Valencian inventory for the study of household consumption, an analysis that would enable us to measure far more accurately the changes in living standards in late medieval society to a degree that is difficult to achieve in other regions of Europe.

Judicial astrology in theory and practice in later medieval Europe.

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Carey, Hilary M

2010-06-01

Interrogations and elections were two branches of Arabic judicial astrology made available in Latin translation to readers in western Europe from the twelfth century. Through an analysis of the theory and practice of interrogations and elections, including the writing of the Jewish astrologer Sahl b. Bishr, this essay considers the extent to which judicial astrology was practiced in the medieval west. Consideration is given to historical examples of interrogations and elections mostly from late medieval English manuscripts. These include the work of John Dunstaple (ca. 1390-1453), the musician and astrologer who is known have served at the court of John, duke of Bedford. On the basis of the relatively small number of surviving historical horoscopes, it is argued that the practice of interrogations and elections lagged behind the theory.

KAEMPFEROL, A FLAVONOID COMPOUND FROM GYNURA MEDICA INDUCED APOPTOSIS AND GROWTH INHIBITION IN MCF-7 BREAST CANCER CELL.

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Yi, Xiaofang; Zuo, Jiangcheng; Tan, Chao; Xian, Sheng; Luo, Chunhua; Chen, Sai; Yu, Liangfang; Luo, Yucheng

2016-01-01

Kaempferol, a natural flavonoid, has been shown to induce cancer cell apoptosis and cell growth inhibition in several tumors. Previously we have conducted a full investigation on the chemical constituents of Gynura medica , kaempferol and its glycosides are the major constituents of G. medica . Here we investigated the growth inhibition and apoptosis induction effect of kaempferol extracted from G. medica . The inhibition effects of kaempferol were evaluated by MTS assay and soft agar colony formation assay. Fluorescence staining and western blotting were be used to study the apoptosis. The structure was identified by 1 H- NMR), 13 C-NMR and ESI-MS analyses. Our results showed that kaempferol's inhibition of MCF-7 breast cancer cell growth may through inducing apoptosis and downregulation of Bcl2 expression. Kaempferol is a promising cancer preventive and therapeutic agent for breast cancer. List of non-standard abbreviations: MTS: 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, HPLC: High-performance liquid chromatography, NMR: Nuclear Magnetic Resonance, ESI-MS Electrospray Ionization Mass Spectral, PARP: Poly ADP-ribose polymerase.

Biochemia Medica has started using the CrossCheck plagiarism detection software powered by iThenticate

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Šupak-Smolčić, Vesna; Šimundić, Ana-Maria

2013-01-01

In February 2013, Biochemia Medica has joined CrossRef, which enabled us to implement CrossCheck plagiarism detection service. Therefore, all manuscript submitted to Biochemia Medica are now first assigned to Research integrity editor (RIE), before sending the manuscript for peer-review. RIE submits the text to CrossCheck analysis and is responsible for reviewing the results of the text similarity analysis. Based on the CrossCheck analysis results, RIE subsequently provides a recommendation to the Editor-in-chief (EIC) on whether the manuscript should be forwarded to peer-review, corrected for suspected parts prior to peer-review or immediately rejected. Final decision on the manuscript is, however, with the EIC. We hope that our new policy and manuscript processing algorithm will help us to further increase the overall quality of our Journal. PMID:23894858

Some Early Optics: Classical and Medieval. Experiment No. 6.

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Devons, Samuel

Information related to the history of optics with emphasis on the classical and medieval periods is presented. Notes are included on experiments dealing with refraction at a plane interface between two media; refraction by transparent spheres; light, color, and reflection by transparent spheres. (Author/SA)

Analysis of ancient and medieval glasses by INAA

International Nuclear Information System (INIS)

Kuleff, I.; Djingova, R.; Penev, I.

1984-01-01

A scheme for instrumental neutron activation analysis of ancient and medieval glasses is proposed. The combination of three irradiations (short time, pile and epithermal) enables the determination of 34 elements. The accuracy of the method is evaluated by analyzing two glass standard reference materials. Results from the analysis of three glasses from different times are presented. (author)

Ocular anatomy in medieval arabic medicine. A review.

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Laios, Konstantinos; Moschos, Marilita M; George, Androutsos

2016-01-01

In medieval Arabic medicine Ophthalmology had a central role. Ocular anatomy was described in many ophthalmological treatises of the physicians of the time. These physicians followed the doctrines of Galen according ocular anatomy, nevertheless their contribution to the history of ocular anatomy was the presentation of ocular anatomical sketches in their manuscripts for the fist time in medical history.

Measuring the Measuring Rod: Bible and Parabiblical Texts within the History of Medieval Literature

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Lucie Doležalová

2018-01-01

Full Text Available In spite of the acknowledged crucial role it had in forming medieval written culture, the Bible and a wide-range of parabiblical texts still remain largely ignored by histories of medieval literatures. The reason for this striking omission of an important group of medieval texts from the 'canonical' narratives is, as I argue, the strong bias in favour of national, secular, fictional, and original texts which shapes literary studies – an inheritance from the nineteenth-century nationalising approaches discussed in the first issue of the Interfaces journal. Of course, the discipline of literary studies and therefore selection, hierarchization, and interpretation are complex social, cultural and political processes where almost anything is possible. It is the environment, the interpretive community, in which the interpretation takes place that has a decisive role. And that, too, is constantly being transformed. Thus, there are no final categories and answers because as long as there are interpretive communities, meanings are generated and operate in new ways. That is why the present discussion does not aim to claim that many of the parabiblical texts are literature and should have been included in the canon of medieval literature. Rather, I examine what the nineteenth-century notion of canon did to these texts and how the current questioning and substantial reshaping of notions of canon can transform our understanding of parabiblical texts.

Rules & legislation on love charms in early medieval Ireland

NARCIS (Netherlands)

Borsje, J.

2010-01-01

Love magic is defined as verbal and material instruments by which erotic and affectionate feelings are believed to be aroused or destroyed in a supernatural way. This is a discussion of love magic as it is presented in early medieval Hiberno-Latin penitentials and Irish legal texts.

Extraction, Modelling and Purification of Flavonoids from Citrus Medica Peel

OpenAIRE

M. Parvathi Nandan; Vangalapati Meena

2015-01-01

Soxhlet extraction technique is widely employed for the extraction and separation of chemical constituents in the medicinal plants. Citrus medica L commonly called as Citron belongs to family Rutaceae, is a slow-growing shrub. It is mainly cultivated for the production of edible fruits which are sour in taste like lime and lemon and the main content of a citron fruit is the thick rind, which is very adherent to the segments. From the phytochemical analysis the peel extract is rich source of p...

Excavating a Silk Road City: the Medieval Citadel of Taraz, Kazakhstan

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Giles Dawkes

2013-10-01

Full Text Available The city of Taraz, located near the southern border with Uzbekistan, is one of the most significant historic settlements in Kazakhstan, and two seasons of fieldwork in the central market-place have revealed a substantial depth of medieval stratigraphy. Despite frequent mentions in Arabic and Chinese written sources, both the form and evolution of this important Silk Road city remain poorly understood. Evidence for a series of successive medieval buildings, including a bathhouse and a Zoroastrian flame shrine, was found in the area of the former citadel. These excavations, undertaken as a joint initiative between the Centre for Applied Archaeology and Kazakh archaeologists, were the first for 50 years in the city and form part of a wider public outreach programme.

The Resources of the Past in Early Medieval Europe

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Gantner, C.; McKitterick, R.M.; Meeder, S.M.

2015-01-01

This volume analyses the importance of history, the textual resources of the past and the integration of Christian and imperial Rome into the cultural memory of early medieval Europe within the wider question of identity formation. The case studies in this book shed new light on the process of

The Desirability of Medieval Germany: Some Observations on an Introductory Course

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Jillings, Lewis G.; Murdoch, Brian O.

1975-01-01

This paper discusses the problems and advantages of a course in Medieval Germany, including history, culture and literature along with language. Attention is given to issues and texts to be studied. (CHK)

Phenotypic and genetic diversity in Sinorhizobium meliloti and S. medicae from drought and salt affected regions of Morocco

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Udupa Sripada M

2010-01-01

Full Text Available Abstract Background Sinorhizobium meliloti and S. medicae are symbiotic nitrogen fixing bacteria in root nodules of forage legume alfalfa (Medicago sativa L.. In Morocco, alfalfa is usually grown in marginal soils of arid and semi-arid regions frequently affected by drought, extremes of temperature and soil pH, soil salinity and heavy metals, which affect biological nitrogen fixing ability of rhizobia and productivity of the host. This study examines phenotypic diversity for tolerance to the above stresses and genotypic diversity at Repetitive Extragenic Pallindromic DNA regions of Sinorhizobium nodulating alfalfa, sampled from marginal soils of arid and semi-arid regions of Morocco. Results RsaI digestion of PCR amplified 16S rDNA of the 157 sampled isolates, assigned 136 isolates as S. meliloti and the rest as S. medicae. Further phenotyping of these alfalfa rhizobia for tolerance to the environmental stresses revealed a large degree of variation: 55.41%, 82.16%, 57.96% and 3.18% of the total isolates were tolerant to NaCl (>513 mM, water stress (-1.5 MPa, high temperature (40°C and low pH (3.5, respectively. Sixty-seven isolates of S. meliloti and thirteen isolates of S. medicae that were tolerant to salinity were also tolerant to water stress. Most of the isolates of the two species showed tolerance to heavy metals (Cd, Mn and Zn and antibiotics (chloramphenicol, spectinomycin, streptomycin and tetracycline. The phenotypic clusters observed by the cluster analysis clearly showed adaptations of the S. meliloti and S. medicae strains to the multiple stresses. Genotyping with rep-PCR revealed higher genetic diversity within these phenotypic clusters and classified all the 157 isolates into 148 genotypes. No relationship between genotypic profiles and the phenotypes was observed. The Analysis of Molecular Variance revealed that largest proportion of significant (P Conclusion High degree of phenotypic and genotypic diversity is present in S

[In process.

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Anagnostou, Sabine

Missionary pharmacy developed as a special type of the European pharmacy from the 16th to the 18th centuries in the overseas missions in the context of the proclamation of the Christian faith, the European expansion and the beginning globalization. As this type of pharmacy was determined by the specific circumstances of the medical-pharmaceutical situation in the mission countries as well as by the knowledge of the missionaries themselves, it can be defined as missionary pharmacy. It followed principally the model of the medieval monastery pharmacy and paved the way for the Medical Mission at the beginning of the 19th century. Different lines of development on various levels of exchange, forming, documenting and transmission of knowledge shaped the concept of the missionary pharmacy. The activities in the context of the missionary pharmacy initiated a global transfer of drugs and the referring pharmaceutical knowledge, which was institutionalized by the pharmacies of the Jesuits and essentially influenced the development of the Materiae medicae and the development of modern pharmacy all around the globe. The trading routes of typical drugs like the Fever bark and compositions can reconstruct this international transfer of knowledge. Still nowadays, knowledge of the missionary pharmacy, especially about genuine plants of the non-European countries, can be interesting for the development of new phytotherapeutics and possibly active substances.

A Morphology of Medieval Notations in the Optical Neume Recognition Project

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Kate Helsen

2017-01-01

Full Text Available The study of medieval notations depends on effective categorization of individual signs in order to facilitate a comprehensive understanding of their musical meaning. Over the past century, chant scholars have developed several kinds of neume tables which arrange and contextualize neumes either according to graphical type, chronology, or scribal tradition. Some neume tables contain longer strings of neumes that link certain notation conventions with performance traditions. The course of neume table development reads like a history of the study of early notations, itself, and reveals the evolving interests and pursuits of the scholars who created them. It also sets the stage for the latest use of the neume table as a reference for document analysis software applied to digital images of medieval manuscripts. Now, instead of presenting a static list of discrete signs, the neume table can be understood as a reflection of the notational variety and nuance of the hundreds of thousands of neumes contained in every book of liturgical chant. On this scale, neume tables help scholars to understand the use of medieval neumes in the same way a linguist understands the morphology of words. This article presents the principles on which this new kind of neume table has been developed and suggests the ways in which this new way of thinking might inform the discipline in the future.

Comunicación y aprendizaje de la ciencia en estudiantes Sordos: la materia y sus transformaciones

OpenAIRE

Vázquez Martínez, Susana

2016-01-01

Esta investigación pretende contribuir al conocimiento de la enseñanza de las ciencias con alumnado Sordo, concretamente, sobre fenómenos relacionados con la transformación de la materia. Se han analizado las percepciones de profesores e intérpretes educativos sobre la enseñanza de las ciencias al colectivo de estudiantes Sordos, los modelos que utilizan para explicar la materia y sus transformaciones y los patrones de interacción de su discurso en el aula. Por último, se valora la implementa...

EFECTO DE LA MATERIA ORGÁNICA Y EL MANEJO SOBRE LA HIDROFOBICIDAD DE SUELOS VOLCÁNICOS

OpenAIRE

Cuevas Becerra, José

2006-01-01

La repelencia al agua o hidrofobicidad de los suelos depende de una fuerte interacción entre las fracciones minerales y orgánicas del suelo. El contenido de materia orgánica condicionara de manera importante el monto de la repelencia, pero no todo el Carbono orgánico es repelente, y mas que el monto total de compuestos orgánicos, son sus características traducidas como calidad de materia orgánica, la que incidirá sobre los montos de hidrofobicidad. Es posible encontrar dos tipos de repelencia...

The effect of fires on the development and appearance of medieval towns

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Domen Kušar

2003-01-01

Full Text Available The occurrence of fires was one of the main dangers, which slowed down development of medieval towns. Frequent fires, whether they occurred due to carelessness, poorly maintained fireplaces and chimneys or military attacks, caused damage, particularly to those towns and buildings, which were constructed of inflammable materials such as timber and straw. In medieval times most towns were built using such materials, except those near the coast. Citizens tried to reduce fire hazards and the consequences of fires. With substitution of inflammable materials, apparatus and with the improved maintenance of fireplaces and chimneys, as well as other preventive measures, they influenced the development of towns and thus changed their architectural image.

Translation Memory and Computer Assisted Translation Tool for Medieval Texts

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Törcsvári Attila

2013-05-01

Full Text Available Translation memories (TMs, as part of Computer Assisted Translation (CAT tools, support translators reusing portions of formerly translated text. Fencing books are good candidates for using TMs due to the high number of repeated terms. Medieval texts suffer a number of drawbacks that make hard even “simple” rewording to the modern version of the same language. The analyzed difficulties are: lack of systematic spelling, unusual word orders and typos in the original. A hypothesis is made and verified that even simple modernization increases legibility and it is feasible, also it is worthwhile to apply translation memories due to the numerous and even extremely long repeated terms. Therefore, methods and algorithms are presented 1. for automated transcription of medieval texts (when a limited training set is available, and 2. collection of repeated patterns. The efficiency of the algorithms is analyzed for recall and precision.

Pervivencias del cuento medieval en la tradición sefardí contemporánea

OpenAIRE

Sánchez-Pérez, María

2015-01-01

El objetivo de este artículo es poner de manifiesto cómo diferentes cuentos medievales de la tradición hispánica han pervivido en la cultura sefardí contemporánea. Para ello, hemos estructurado el trabajo en varias partes: una introducción, una comparación entre el cuento medieval y la konseja sefardí, un breve estado de la cuestión y, posteriormente, un análisis comparativo de tres casos concretos. The aim of this article is to highlight how different medieval tales of the ...

Three cases of feet and hand amputation from Medieval Estremoz, Portugal.

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Fernandes, Teresa; Liberato, Marco; Marques, Carina; Cunha, Eugénia

2017-09-01

Peri-mortem limb amputations are rarely reported in the paleopathological literature. The cases reported here concern severing of both hands and feet observed in three adult male skeletons, exhumed from the medieval Portuguese necropolis of Rossio do Marquês de Pombal, Estremoz, Portugal. The fact that they were found in the same site, in graves placed side by side, that all are young males, and that the three skeletons show similar perimortem injuries, make this a unique case meriting detailed analysis. Considering the lesions' location and pattern, as well as historical data, we hypothesize that this is a case of amputation as a consequence of judicial punishment. Estremoz was an important city in sustaining the Royal power at a regional scale during the medieval period. Copyright © 2017 Elsevier Inc. All rights reserved.

PISA: números, estandarización de la conducta y la alquimia de las materias escolares

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Thomas S. Popkewitz

2013-01-01

Full Text Available Este artículo examina la red de prácticas que confieren inteligibilidad a la organización del conocimiento de las materias escolares que hace PISA. El programa PISA es tratado como un acontecimiento histórico. Su estudio consiste en hacer visible los principios que ordenan y clasifican los objetos “vistos” y que actúan sobre el “conocimiento práctico” de las materias escolares. La política de PISA, a mi juicio, son los principios que rigen lo que los chicos deberían conocer, cómo ese conocimiento se hace posible, y el estudio de la inclusión y exclusión incorporadas en estas prácticas. La primera parte analiza históricamente la transformación de los números en “hechos”, una presunción que posibilita las comparaciones de PISA. En la segunda parte, dirige la atención a los principios de las materias escolares que ordenan y clasifican los “hechos” de las mediciones de PISA.

Unriddling of ancient-medieval culture by PIXE

International Nuclear Information System (INIS)

Uda, M.

1997-01-01

Some examples are given for unriddling of ancient-medieval culture by PIXE. Effectiveness of PIXE to analyze art and archaeological objects is also explained. Objects employed here are 1) red, yellow, blue and white pigments painted on sun-dried bricks excavated in Egypt, 2) ancient glass beads used in the Near East, 3) South American mummy hair, 4) ancient slag excavated from Kansai-district, Japan 5) ink used by Galileo Galilei and 6) Renaissance style enameled gold jewelry. (author)

The Function of the Medieval in Jean-Jacques Rousseau's Nouvelle Heloise : A Rereading of the Abelard and Heloise Motif

NARCIS (Netherlands)

Montoya, Alicia C.

2010-01-01

Jean-Jacques Rousseau's critical rewriting in his Nouvelle H,lo medieval works-the letters of Ab,lard and H,lo medieval played in his own moral vision. This article both identifies a possible eighteenth-century

Morbidity, rickets and long-bone growth in post-medieval Britain--a cross-population analysis.

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Pinhasi, R; Shaw, P; White, B; Ogden, A R

2006-01-01

Vitamin D deficiency rickets is associated with skeletal deformities including swollen rib junctions, bowing of the legs, and the flaring and fraying of the wrist and long-bone metaphyses. There is, however, scarce information on the direct effect of rickets on skeletal growth in either present or past populations. The study investigated the effect of vitamin D deficiency rickets on long-bone growth in two post-medieval skeletal populations from East London (Broadgate and Christ Church Spitalfields). Subsequently, inter-population growth variations in relation to non-specific environmental stress (dental enamel defects), industrialization, urbanization and socio-economic status during infancy (birth to 3 years) and early childhood (3-7 years) were examined. Data on long-bone diaphyseal length dimensions and stress indicators of 234 subadults from Anglo-Saxon, late medieval and post-medieval archaeological skeletal samples were analysed using both linear and non-linear growth models. Rickets had no effect on the growth curves for any of the long bones studied. However, pronounced variations in growth between the four populations were noted, mainly during infancy. The diaphyseal length of long bones of Broadgate were significantly smaller-per-age than those of Spitalfields and the other samples up to the age of 4 years, and were associated with a high prevalence of enamel defects during early infancy. Socio-economic status, rather than urbanization, industrialization or rickets, was the central factor behind the observed differences in growth among the post-medieval populations. The observed inter-population growth variations were only significant during infancy.

Orientation of medieval churches of Morava school

OpenAIRE

Tadić Milutin; Gavrić Gordana

2012-01-01

In this paper we present the mathematical and topographic analysis of orientation of the most significant churches (11) of Morava school, the last style in architecture of medieval Serbia whose executors were chief architects. The deviation from equinox East of the main axis of each church and the dates when the Sun rises on the physical horizon, in the extension of the main axis, have been calculated. These were the dates when the church could have been oriented towards the rising Sun....

Retos constitucionales en materia de género

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María Esther Seijas Villadangos

2015-06-01

Full Text Available La Constitución es la norma más valiosa sobre la que se erigen los pilares de los Estados democráticos contemporáneos. Reflexionar desde la Constitución y con una perspectiva de género ha sido el leit motiv del número 10 de la Revista “Cuestiones de Género: de la igualdad y la diferencia”, titulado Retos constitucionales en materia de género. Los atributos con los que se ha querido afrontar esta tarea son los siguientes: legalidad, globalidad, particularidad, humanidad y pragmatismo.

[Subjectivity and objectivity, semiotics and diagnosis. An approach to the medieval concept of illness].

Science.gov (United States)

Riha, O

1996-01-01

Relying on their patients' complaints, medieval physicians did not discriminate theoretically between sickness and health. As for the types of illness, there were two different concepts of disease: The semiotic tracts (sphygmology, uroscopy, hematoscopy) describe signs of dyscrasia and locus affectus, while the medical handbooks combine symptoms like fever, pain, nausea, constipation etc. with the signs of pulse, urine and blood. The term "diagnosis" should be used only for this latter type of disease. Because of the ancient model of humoral pathology and because of the deductive construction of symptomatology, "medieval" illnesses cannot be compared with "ours".

Primstav and Apocalypse : Time and its Reckoning in Medieval Scandinavia

OpenAIRE

Powell, Avery Myers

2011-01-01

This work is intended as an exploration of methods of time-reckoning and conception in Medieval Scandinavia. In the main this is tied to the dynamism between a duality: that of the cyclical and linear models of time’s progression. Involved in this study are sources verbal and pictoral.

From the Dictionary of Medieval Latin in Czech Lands. Gracocenderius

Czech Academy of Sciences Publication Activity Database

Šedinová, Hana

2017-01-01

Roč. 140, č. 3/4 (2017), s. 455-470 ISSN 0024-4457 Institutional support: RVO:67985955 Keywords : ravens * ancient and medieval zoology * Latin names of birds * Bartholomaeus de Solencia dictus Claretus * Aristotle * Aristoteles Latinus * Michael Scotus * Thomas of Cantimpré Subject RIV: AI - Linguistics OBOR OECD: Specific languages

Living History with a Medieval Banquet in the Alhambra Palace.

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Shabbas, Audrey

1996-01-01

Recommends that students learn about Islamic civilization by presenting a "medieval banquet in the Alhambra Palace." Provides information about middle eastern culture and history that students could use to plan and produce the banquet. Includes a list of 26 "guests" who would be role-played by students. (CFR)

Social inequality and death as illustrated in late-medieval death dances

NARCIS (Netherlands)

J.P. Mackenbach (Johan)

1995-01-01

textabstractLate-medieval murals and books of the then-popular "dances of death" usually represented the living according to their social standing. These works of art thus provide an interesting opportunity to study the relationship between social inequality and death

Medieval Japan. Grade 7 Model Lesson for Standard 7.5. World History and Geography: Medieval and Early Modern Times. California History-Social Science Course Models.

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Zachlod, Michelle, Ed.

California State Standard 7.5 is delineated in the following manner: "Students analyze the geographic, political, economic, religious, and social structures of medieval Japan." Seventh-grade students describe the significance of Japan's proximity to China and Korea and the influence of these countries on Japan; discuss the reign of…

The language and style of Latin rubrics in medieval liturgical Easter drama

Czech Academy of Sciences Publication Activity Database

Vršecká-Kvízová, Kateřina

-, č. 71 (2013), s. 267-280 ISSN 1376-7453 R&D Projects: GA MŠk(CZ) LD13043 Institutional support: RVO:67985955 Keywords : Easter drama * Medieval Latin * Latin rubrics Subject RIV: AI - Linguistics

The ethics of heroism in medieval and American Indian tales.

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Scott, A

1990-01-01

Oral-traditional stories detail their heroes' growth through a narrative pattern of exile and return that places the heroes in situations repeatedly challenging their strength and resolve. Through the motif of the quest, medieval and American Indian tales alike reaffirm general psychological truths that bear upon our understanding of human nature. Stories about heroes are stories about us: about our desires to grow up, to defeat death, to prove ourselves in difficult situations, and to achieve recognition or admiration among our peers (Becker, 1973, p. 4). In this way, medieval and American Indian tales are about self-actualization. They maintain that "one has within oneself proclivity toward growth and unity of personality ... and an automatic thrust toward expression" of these qualities (Yalom, 1980, p. 9). All forms of literature, however, reflect ideas peculiar to their cultures. The ways in which these basic human truths are represented in medieval and American Indian tales suggest the differing religious or social concerns that have informed these truths and have given them shape. To a large degree, the medieval knight's view of "self" and "other" encompasses the view that Western humanity has had (and continues to have) of itself. This is a view conditioned upon the superiority of the "self" as measured against the inferiority of the "other," reinforced through existing social (hierarchial) and religious (Judeo-Christian) codes of behavior. Such codes are not only inadequate to the task of interpreting American Indian perceptions of "self" and "other," they are inimical to the ethical foundation underlying them. Scott Momaday remarks that "you cannot understand how the Indian thinks of himself in relation to the world around him unless you understand his conception of what is appropriate; particularly what is morally appropriate within the context of that relationship" (Basso, 1984, p. 46). For the American Indian hero, self-actualization is self

Corruption as a Legacy of the Medieval University: Financial Affairs

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Osipian, Ararat L.

2004-01-01

Looking back upon the centuries one would suspect that in earlier ages universities of medieval France and Italy were very different from the multiplicity of organizational and institutional forms of higher education institutions in modern times, and yet one would be surprised how much these old "universitas" and modern universities have…

The "Endura" of The Cathars' Heresy: Medieval Concept of Ritual Euthanasia or Suicide?

Science.gov (United States)

Tsiamis, Costas; Tounta, Eleni; Poulakou-Rebelakou, Effie

2016-02-01

The aim of the study is to explore the medieval concepts on the voluntary death of severely sick people, as they emerge through the endura (endurance) of the heresy of the Cathars in France (twelfth to fourteenth centuries). The endura was the prerequisite act of repentance that would allow the fallen soul to return to heaven. The endura was a necessary act of repentance, after the performance of a ceremonial purification of the soul (consolamentum), and consisted of the patients' voluntary abstention from vital food. The consolamentum and endura could be performed in the final stage of a disease with the consent of the patients or their relatives. The role of the Cathar physician was only to determine the severity of the disease and the forthcoming death of the patient. The physician was not allowed to take steps that would deprive the life of the patient, and the performance of the ritual endura was duty of the spiritual leaders of the community. The modern ethical approach to this subject is dictated by the medieval belief on the salvation of the soul and tries to answer the question of whether the endura could be seen as a medieval concept of a ritual euthanasia or fell within the theological sin of suicide.

A lime based mortar for thermal insulation of medieval church vaults

DEFF Research Database (Denmark)

Larsen, P.K.; Hansen, Tessa Kvist

A new mortar for thermal insulation of medieval church vaults was tested in a full scale experiment in Annisse Church, DK. The mortar consists of perlite, a highly porous aggregate, mixed with slaked lime. These materials are compatible with the fired clay bricks and the lime mortar joints....... The lambda-value of the insulation mortar is 0.08 W/m K or twice the lambda-value for mineral wool. The water vapour permeability is equal to a medieval clay brick, and it has three times higher capacity for liquid water absorption. The mortar was applied to the top side of the vaults in a thickness of 10 cm......, despite a water vapour pressure gradient up to 500 Pa between the nave and attic. There was no reduction in energy consumption the first winter, possibly due to the increased heat loss related to the drying of the mortar....

Medieval Europe. Grade 7 Model Lesson for Standard 7.6. World History and Geography: Medieval and Early Modern Times. California History-Social Science Course Models.

Science.gov (United States)

Zachlod, Michelle, Ed.

California State Standard 7.6 is delineated in the following manner: "Students analyze the geographic, political, economic, religious, and social structures of the civilizations of Medieval Europe." Seventh-grade students study the geography of Europe and the Eurasian land mass; describe the spread of Christianity north of the Alps and…

CARACTERIZACIÓN DE LA MATERIA ORGÁNICA DISUELTA EN AGUA SUBTERRÁNEA DEL VALLE DE TOLUCA MEDIANTE ESPECTROFOTOMETRÍA DE FLUORESCENCIA 3D

OpenAIRE

Rosa María FUENTES RIVAS

2015-01-01

La materia orgánica en el agua está compuesta por miles de componentes: partículas macroscópicas, coloides o macromoléculas disueltas. Caracterizar la materia orgánica disuelta en el agua para abastecimiento humano es esencial para establecer sus condiciones físicas y los índices de contaminación del agua. La materia orgánica disuelta en 49 muestras de agua subterránea cercanas a la zona industrial Toluca-Lerma (Valle de Toluca, Toluca, Estado de México) fueron caracterizadas a través de la d...

GC-MS analysis and antimicrobial activity determination of Citrus medica L. var proper leaf essential oil from South Sulawesi against skin pathogen microorganism

Science.gov (United States)

Aliyah; Himawan, A.; Rante, H.; Mufidah; Ningsih, D. R.

2017-11-01

A research about Citrus medica L. var sarcodactylis had been conducted and it showed a significant antimicrobial activity, thus drive our curiosity to investigate the other variety from the same species, Citrus medica L. var proper. This research focuses in chemical compound study and antimicrobial activity screening against Staphylococcus aureus, Propionibacterium acne, and Candida albicans of Citrus medica L. var Proper leaves’ essential oil. The essential oil is distillated from fresh leaves by hydrodestillation. The chemical compound was analysed using GC-MS instrument while the antimicrobial activity was tested using disk diffusion method. The results showed that the major component of the essential oil was Z-citral, citral and limonene compounds. The antimicrobial activity test results against the test microorganism are 9.15±0.15 mm, 11.15±1.3 mm and 8.02±0.48 mm, consecutively, for Staphylococcus aureus, Propionibacterium acne and Candida albicans.

La materia en condiciones extremas de densidad y temperatura

OpenAIRE

Morones Ibarra, José Rubén

2013-01-01

El estudio de las propiedades de la materia cuando se encuentra sometida a condiciones extremas de temperatura y presión ha llamado la atención de los físicos nucleares y de partículas elementales debido a la importancia que este tema tiene para conocer las condiciones iniciales del universo. En los primeros instantes del Gran Estallido (Big Bang) el universo era una región muy pequeña del espacio y por lo tanto su densidad y temperatura eran enormes. Para ente...

Origen y evolución urbana de Alcañiz. De la villa medieval a la ciudad renacentista

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Juan José Barragán Villagrasa

2011-01-01

Full Text Available La ciudad de Alcañiz (Aragón constituye un ejemplo de las reformas que el urbanismo renacentista impulsó en las villas medievales, ligado en este caso al desarrollo del Concejo, y la progresiva independencia municipal respecto al señorío de la Orden de Calatrava, con sede en el castillo. Hemos indagado en el modelo de urbanismo medieval impulsado por los calatravos desde la repoblación del territorio, formado por dos líneas de muralla, una de ellas inédita, y que hemos denominado «muralla alta». Desde el Concejo medieval, con sede en las Casas Comunes, se desarrolla un nuevo modelo de urbanismo, con nuevos espacios públicos como la Plaza Mayor, una trama de calles más anchas y regulares, y el desarrollo de una edificación más estandarizada, que convivirá con lo culminando en la construcción de la Casa Consistorial por el Concejo posmedieval, institución que actualmente conocemos como Ayuntamiento.The town of Alcañiz, in Aragon, is a good example of the reforms that Renaissance town plannings spread in medieval towns. In this case, it is linked to the development of the town Council, and the progressive local independence from the Calatrava Lordship, whose headquarter were inside the castle. We have researched the medieval town planning promoted by the Calatravos since the repopulation of the territory. It is formed by two lines of city walls, one of which was unknown and we have called it «the high wall». From the medieval Council House, sited in the Common Houses, a new model of urbanism is developed, with new public spaces like the Main Square, wider and more regular street patterns and the development of a more standarized way of building that has co-existed with the medieval quarters until the present days.

Il ripensamento e la ridistribuzione suggeriti ai sistemi giuridici liberaldemocratici dalla naturale metamorfosi della domanda di libertà in materia religiosa

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Sara Domianello

2011-04-01

Full Text Available Testo, corredato delle note, dell’intervento al secondo Convegno nazionale di studio dell’A.D.E.C. “Libertà religiosa tra declino o superamento dello Stato nazionale” (Macerata, 28-30 ottobre 2010, destinato alla pubblicazione degli Atti. SOMMARIO: 1. La retromarcia da ingranare (ovvero: il ripensamento circa l’opportunità di trasferire interamente la tutela dei diritti di libertà fondamentali dall’attività parlamentare a quella giurisprudenziale in senso lato – 2. La ristrutturazione da avviare (ovvero: la ridistribuzione delle competenze in materia di pubblico intervento a garanzia dei diritti di libertà in materia religiosa – 3. Il dato da cui muovere (ovvero: la metamorfosi della domanda di libertà in materia religiosa nei sistemi liberaldemocratici.

El electrón en la materia condensada

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Rojo, Juan Manuel

1997-10-01

Full Text Available Not available.Se lleva a cabo una discusión sobre las características de los estados de los electrones en la materia condensada. Se analizan tres propiedades importantes de dichos estados: 1 el canje entre electrones, responsable del magnetismo, con énfasis en sistemas de interés actual como aglomerados pequeños y materiales amorfos; 2 el apareamiento entre electrones con una nota sobre la superconductividad a alta temperatura y 3 el túnel de electrones, mostrándose algunos ejemplos recientes de la aplicación del túnel al estudio a escala atómica de fenómenos de superficie.

Protracted fluvial recovery from medieval earthquakes, Pokhara, Nepal

Science.gov (United States)

Stolle, Amelie; Bernhardt, Anne; Schwanghart, Wolfgang; Andermann, Christoff; Schönfeldt, Elisabeth; Seidemann, Jan; Adhikari, Basanta R.; Merchel, Silke; Rugel, Georg; Fort, Monique; Korup, Oliver

2016-04-01

River response to strong earthquake shaking in mountainous terrain often entails the flushing of sediments delivered by widespread co-seismic landsliding. Detailed mass-balance studies following major earthquakes in China, Taiwan, and New Zealand suggest fluvial recovery times ranging from several years to decades. We report a detailed chronology of earthquake-induced valley fills in the Pokhara region of western-central Nepal, and demonstrate that rivers continue to adjust to several large medieval earthquakes to the present day, thus challenging the notion of transient fluvial response to seismic disturbance. The Pokhara valley features one of the largest and most extensively dated sedimentary records of earthquake-triggered sedimentation in the Himalayas, and independently augments paleo-seismological archives obtained mainly from fault trenches and historic documents. New radiocarbon dates from the catastrophically deposited Pokhara Formation document multiple phases of extremely high geomorphic activity between ˜700 and ˜1700 AD, preserved in thick sequences of alternating fluvial conglomerates, massive mud and silt beds, and cohesive debris-flow deposits. These dated fan-marginal slackwater sediments indicate pronounced sediment pulses in the wake of at least three large medieval earthquakes in ˜1100, 1255, and 1344 AD. We combine these dates with digital elevation models, geological maps, differential GPS data, and sediment logs to estimate the extent of these three pulses that are characterized by sedimentation rates of ˜200 mm yr-1 and peak rates as high as 1,000 mm yr-1. Some 5.5 to 9 km3 of material infilled the pre-existing topography, and is now prone to ongoing fluvial dissection along major canyons. Contemporary river incision into the Pokhara Formation is rapid (120-170 mm yr-1), triggering widespread bank erosion, channel changes, and very high sediment yields of the order of 103 to 105 t km-2 yr-1, that by far outweigh bedrock denudation rates

The Religious Significance of the Medieval Body and Flannery O'Connor's Fiction

National Research Council Canada - National Science Library

Novak, Kenneth

2002-01-01

Flannery O'Connor based what she called her "anagogic vision" on the medieval way of seeing the world that allowed the reader of a text to discern "different levels of reality in one image or one situation...

Corruption as a Legacy of the Medieval University

OpenAIRE

Osipian, Ararat

2004-01-01

Looking back upon the centuries one would suspect that in earlier ages universities of medieval France and Italy were very different from the multiplicity of organizational and institutional forms of higher education institutions in modern times, and yet one would be surprised how much these old universitas and modern universities have in common. The increasing scale and scope of corruption in higher education in the former Soviet Bloc as well as numerous other countries urges a better unders...

Genetic research at a fivefold children's burial from medieval Berlin.

Science.gov (United States)

Rothe, Jessica; Melisch, Claudia; Powers, Natasha; Geppert, Maria; Zander, Judith; Purps, Josephine; Spors, Birgit; Nagy, Marion

2015-03-01

Berlin originated from the two twin cities Berlin and Cölln, which both were founded at the beginning of the 13th century. However the real date of their foundation as well as the origin of the first settlers is still unknown. On the Berlin site the historic city center is still visible in the Nikolaiviertel, but the medieval origin of Cölln disappeared almost completely. In 2007 a large scale excavation, which comprised an area of about 1700m(2) of the historical center of the St. Peters church, recovers the remains of Cölln's first citizens and span a period of 500 years of medieval population. Here we present the first genetic analysis of a fivefold children's burial from excavations in Berlin. The genetic data unveiled next to ancestry and eye color data also the kinship and the gender of the five individuals. Together with the archeological context the new gained information help to shed more light on the possible reasons for this burial. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

An Introduction to the Medieval English: The Historical and Literary Context, Traces of Church and Philosophical Movements in the Literature

Science.gov (United States)

Behtash, Esmail Zare; Toroujeni, Seyyed Morteza Hashemi; Samani, Farzane Safarzade

2017-01-01

The Transition from Greek to medieval philosophy that speculated on religion, nature, metaphysics, human being and society was rather a rough transition in the history of English literature. Although the literature content of this age reflected more religious beliefs, the love and hate relationship of medieval philosophy that was mostly based on…

Pectin extraction from Citron peel (Citrus medica Linn. and its use in food system

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Rojanakorn, T.

2006-11-01

Full Text Available Screening experiments using 25-1 fractional factorial design showed that pH, temperature, and extracting time were the main factors affecting the amount and quality of extracted pectin from Citrus medica Linn. Optimum condition of pectin extraction was studied using central composite design (CCD. Mathematical models relating pH, temperature and extracted time to amount of extracted pectin, equivalent weight, methyl content and anhydrogalacturonic acid content were established. Based on the mathematics models, the condition of pH 2, 100ºC and 105 min was found to be the optimum conditions for pectin extraction from Citrus medica Linn. Mathematical and experimental results were verified. The use of extracted pectin as a gelling agent in pineapple jam revealed no significant difference in gel consistency compared to that of commercial pectin grade 150 (p>0.05. However, the commercial pectin had a higher liking score on the spreadability, texture and overall liking. As a stabilizer in chocolate pasteurised milk, 0.2% of the extracted pectin was required to prevent precipitation of chocolate powder with the similar viscosity obtained from 0.06% κ-carageenan

The Disputed Authorship of a Medieval Text: A New Solution to the Attribution Problem in the Case of Guillaume D’Angleterre

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Maria Slautina

2012-11-01

Full Text Available This paper presents a case of disputed authorship concerning a literary medieval text, the Old French romance Guillaume d’Angleterre, and describes a new attempt to use the mathematical method of authorship attribution called the "method of pattern recognition”. After presenting an overview of previous approaches to the problem of the authorship of this text, I argue for the advantages of a statistical syntactic based method for authorship attribution of medieval texts. The method of pattern recognition consists in the identification of a domain of syntactic parameters and a measurement of the proximity or distance of texts as located in a multi-dimensional syntactic space. I find that the medieval text most likely belongs to Chrétien de Troyes, one of the most famous French authors of the twelfth century. I present for the first time an attempt to apply the method of pattern recognition to determine the authorship of a medieval text written in Old French.

Secado de primeras materias cerámicas por atomización

OpenAIRE

Editorial, Equipo

2016-01-01

El secado por atomización consiste en inyectar una suspensión de arcilla, de pasta o de cualquier otra materia, en aire seco y caliente. El agua se evapora y las partículas, totalmente secas o con el contenido deseado en humedad, se separan de la corriente de aire. Este proceso es muy adecuado para la preparación de pastas para prensado en seco.

Erros de medicação em hospitais: uma análise bioética dos aspectos jurídicos e de saúde

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Gabriela Souza Schumacher

2013-06-01

Full Text Available Introdução: O tema dos erros de medicação envolve vários aspectos - éticos, morais, jurídicos, sociais, profissionais, assistenciais, entre outros - merecendo uma reflexão abrangente. Os aspectos éticos referem-se principalmente à adequação das ações frente aos erros e os aspectos jurídicos estão relacionados diretamente com a aferição da responsabilidade civil nos casos da ocorrência de danos. Este estudo busca estabelecer relações entre o Direito, a Saúde e a Bioética, em uma perspectiva interdisciplinar, por meio da avaliação dos acórdãos referentes a erros de medicação em hospitais na jurisprudência do Rio Grande do Sul. Materiais e Método: Foi realizada uma pesquisa qualitativa, de análise de conteúdo documental, em acórdãos colhidos na base de dados eletrônica do Tribunal de Justiça do estado do Rio Grande do Sul. O descritor utilizado para busca foi: erro de medicação em hospitais. Resultados e Discussão: foram localizados 43 acórdãos na base de dados no período de 1995 a 2011. Destes, apenas 6 acórdãos referem-se a erros de medicação especificamente, sendo que 2 não estão disponíveis na íntegra. Foram analisados os quatro acórdãos envolvendo erros de medicação. Nos 4 acórdãos os demandados foram: 3 hospitais, 1 município e 1 médico. Todas as decisões foram favoráveis aos demandantes. Considerações Finais: O conceito de erro de medicação, embora utilizado na área da saúde e por órgãos oficiais, não tem sido utilizado no Poder Judiciário, o que demonstra que uma maior aproximação das áreas envolvidas, incluindo uma melhor comunicação, é necessária para uma adequada compreensão do tema.

Presentación del Departamento de Física Nuclear y Física Estadística del Instituto de Estructura de la Materia del CSIC

OpenAIRE

García Borge, María José

2007-01-01

Presentado en el IV Curso de Iniciación a la Investigación en Estructura de la Materia: Desde las partículas subatómicas hasta los compuestos moleculares (Instituto de Estructura de la Materia, CSIC, 28-30 de Marzo de 2007).

EVALUACIÓN AMBIENTAL PARA PROCESOS QUE USAN RESIDUOS DE LA INDUSTRIA DE LOS BIOCOMBUSTIBLES COMO MATERIAS PRIMAS

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Mónica Julieth Valencia Botero

Full Text Available La industria creciente de los biocombustibles genera grandes cantidades de residuos que tienen alto potencial para la obtención de productos con alto valor agregado. En el presente documento se lleva a cabo el análisis de ciclo de vida (ACV para el glicerol y el bagazo de caña de azúcar durante su producción y para su uso como materia prima en cuatro procesos diferentes. El objetivo fue determinar el impacto ambiental de los cuatro procesos, por medio de la cuantificación de gases de efecto invernadero (GEI asociados al ciclo de vida. Los resultados indican que las emisiones de GEI asociadas a los procesos que utilizan el glicerol como materia prima son mayores que las emisiones de GEI para los procesos que involucran bagazo de caña de azúcar, pero que el aprovechamiento del glicerol podría considerarse más eficiente, ya que las emisiones por unidad de masa en el uso del glicerol son 75% inferiores a las emisiones calculadas para los procedimientos utilizando bagazo de caña como materia prima.

Violent behavior patterns: possible homeopathic remedies Modelos de conducta violenta: posibles remedios homeopáticos Padrões de conduta violenta: possíveis medicamentos homeopáticos

OpenAIRE

Carmela Maria Vieira Pedalino; Jussara Meyer Osielski; Fernando Antônio Cardoso Bignardi; Célia Regina Barollo

2008-01-01

The authors discuss violence as a current epidemics and violent behavior in children and adolescents. They present a repertory study including the characteristic and peculiar symptoms of 12 patients, with clinical diagnoses of Attention Deficit Hyperactivity Disorder (ADHD), Conduct Disorder and Oppositional Defiant Disorder, and the symptoms corresponding to the diagnostic criteria in the DSM-IV transcribed in repertory language. The result is a materia medica for patterns of violent behavi...

A Review of The Architecture of the Scottish Medieval Church 1100–1560

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Ian Campbell

2013-01-01

Full Text Available If ever a book could be described as a ‘magnum opus’ it is this: indeed it is a summa. Richard Fawcett has been publishing on Scottish medieval architecture, mainly ecclesiastical, for three decades, ranging from articles on minute changes in Gothic mouldings (the subject of his doctoral research at the University of East Anglia such as ‘Dunblane Cathedral: evidence for a change in the design of the nave’ (1982 to a survey of architecture between 370 and 1560, Scottish Architecture from the Accession of the Stewarts to the Reformation (1994. For much of that time he was an Inspector of Ancient Monuments for Historic Scotland, allowing him unfettered access to all the key monuments for most of which he has written authoritative guidebooks. However, besides Scotland, his knowledge of other European medieval architecture, especially in England, France and the Low Countries is encyclopaedic. His researches have made unsustainable the inferiorist attitude that Scottish medieval architecture was insular and backward, by pointing out countless foreign parallels, which demonstrate that Scotland’s patrons and masons were always aware of contemporary developments beyond its borders and shores. This monumental book brings together the fruits of these years of study into a rich synthesis. At last MacGibbon and Ross’ groundbreaking Ecclesiastical architecture of Scotland (1896-7 has been superseded.

Adolescent health in medieval Serbia: signs of infectious diseases and risk of trauma.

Science.gov (United States)

Djurić, M; Janović, A; Milovanović, P; Djukić, K; Milenković, P; Drasković, M; Roksandic, M

2010-04-01

Although pattern of health in adults has been frequently assessed in past human populations, health status of adolescents as a distinct life stage has usually been overlooked. Inconsistency in number and meaning of recognised age categories in anthropological literature, as well as chronological age ranges used to define them, further complicate the interpretation of adolescent health. In this study, we analysed signs of pathological conditions on skeletal remains of 81 adolescents from a medieval site of Stara Torina (northern Serbia). Diagnostic palaeopathological procedures comprised gross examination, digital radiography, and histological analysis. Skeletal signs of anaemia such as cribra orbitalia and other porotic phenomena as well as signs of non-specific bone infection were observed frequently, while evidence of bone trauma was recorded in a very low percentage of individuals. In addition, we recorded two conditions relatively rarely observed in palaeopathological contexts: a case of skull and vertebral asymmetry indicative of congenital muscular torticollis, and a case of a fibrous cortical defect on distal femur. Comparison with available information from other medieval adolescent samples from Serbia demonstrated that while mortality was relatively constant throughout the sample, Stara Torina showed a much higher occurrence of bone disease. Characteristics of observed skeletal conditions, supported by available historical reports, suggest that the health of medieval adolescents in the examined population was most significantly affected by infectious processes. Copyright 2010 Elsevier GmbH. All rights reserved.

Managing Uncertainty through Profit sharing Contracts from medieval Italy to Silicon Valley

NARCIS (Netherlands)

Brouwer, M.

2005-01-01

Organizational innovation is essential to economic development. But, the way successful societies have organized new ventures has been remarkably similar in both past and present. The commenda organizations of medieval Italy shared many characteristics with modern startups that are financed by

The structure of the medieval town of Rupea

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Borcoman, M.

2010-11-01

Full Text Available The town of Rupea, set up at the beginning of the 12th century, was the capital of the county of Rupea between 1337 and 1876. Its urban structure and organization prove that it belonged to group of Transylvania’s German medieval towns. Here, alongside with the German (established in the central area, Romanians lived in the outskirts. This structure was preserved until the early 1800s, and even until nowadays although the initial ethnical composition has altered.

Alteration of medieval stained-glasses. Contribution to the long-term behaviour of vitrified wastes

International Nuclear Information System (INIS)

Sterpenich, J.

1998-01-01

In this work, the behaviour of glasses during alteration have been studied in two different ways: 1)study of the alteration of medieval stained-glasses 2)experimental leaching of modelled glasses. Medieval stained-glasses have a silico-calcic and alkaline composition. It appears three different alteration modes for these glasses: 1)by condensation waters 2)by atmospheric agents 3)by porosity waters and humic acids. A chemical study of the altered areas has allowed to understand the alteration behaviour of a lot of elements: in particular transition elements, heavy metals and some rare earths. On the other hand, two vitrified wastes and a glass having the same composition of the potassic medieval stained-glasses have been leached in a static mode (pH=1 to 10, T=20 to 80 degrees Celsius, T=12 hours to 6 months). These experiments have revealed that the alteration mechanisms depend on the pH of the solution and on the chemical composition of the glass. An increasing durability of glasses in terms of the global polymerization degree has been revealed too. At last, the behaviours of glasses during alteration, observed with natural and experimental conditions, show that it is necessary to study natural analogous for predicting the long-term behaviour of vitrified wastes. (O.M.)

Parámetros de Transferencia de Materia en el Secado de Frutas Mass Transfer Parameters in Fruit Drying

OpenAIRE

Sebastião R Ferreira; Antônio R. S Costa

2009-01-01

Se desarrolló un modelo analítico para obtención de parámetros de transferencia de materia en el secado de frutas. El modelo considera la disminución del radio de las frutas durante el proceso de secado. Con el modelo matemático se predice simultánemente el coeficiente externo de transferencia de materia k m y la difusividad de agua en los frutos D AB. Para probar el modelo se obtuvo en forma expermental datos de masa de agua M A en la fruta versus el tiempo de secado t, además del radio inic...

Restorian of outdoor plaster pavement floors in a medieval Czech castle

Czech Academy of Sciences Publication Activity Database

Slížková, Zuzana; Drdácký, Miloš

2008-01-01

Roč. 14, č. 3 (2008), s. 81-98 ISSN 1355-6207 R&D Projects: GA ČR(CZ) GA103/06/1609 Institutional research plan: CEZ:AV0Z20710524 Keywords : floor plaster * metakaoline modified mortar * medieval castle rampart * non-standard testing Subject RIV: AL - Art, Architecture, Cultural Heritage

The Accreditation of Hildegard Von Bingen as Medieval Female Technical Writer

Science.gov (United States)

Rauch, Susan

2012-01-01

Although scholars have acknowledged technical texts written during the Middle-Ages, there is no mention of "technical writer" as a profession except for Geoffrey Chaucer, and historically absent is the accreditation of medieval female writers who pioneered the field of medical-technical communication. In an era dominated by identifiable medieval…

Orientation of English Medieval Parish Churches

Science.gov (United States)

Hoare, Peter G.

Our understanding of the alignment of English medieval parish churches, after more than three centuries of research, is far from complete. The arrangement of relatively few structures has been explained beyond reasonable doubt, and tests of the overwhelmingly popular festival orientation theory are often insufficiently rigorous to provide convincing answers. Much work remains to be done, including verifying and analyzing some of the existing raw data, determining whether the present church was dedicated at the time of construction, examining wills for evidence of early dedications, measuring the effect of eastern horizons on sunrise azimuths, and consulting excavation reports to assess whether earlier buildings may have influenced the arrangement of those churches that replaced them.

Tablet-woven and tabby-woven braids from the Czech late medieval archaeological findings

Czech Academy of Sciences Publication Activity Database

Březinová, Helena

2010-01-01

Roč. 23, - (2010), s. 47-51 ISSN 0860-0007 Institutional research plan: CEZ:AV0Z80020508 Keywords : textile fragments * tablet -woven braids * tabby-woven braids * late medieval Subject RIV: AC - Archeology, Anthropology, Ethnology

Changing Settlements and Landscapes: Medieval Whittlewood, its Predecessors and Successors

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Richard Jones

2006-09-01

Full Text Available This article presents an interpretative synthesis of the development of a medieval landscape in the English Midlands. It explores its administrative organisation and divisions; the exploitation of its woodland, pasture, and arable resources; and the creation, growth, and decline of its villages, hamlets and farmsteads. It takes as its central theme two inter-related oppositions: continuity and change, moments and processes. In particular it examines the role these played in the development of varying settlement morphologies (the area under investigation contains both nucleated and dispersed settlement forms and in the introduction and demise of the open field system. The article is based on the investigation of twenty-one medieval villages and hamlets and their surrounding landscapes, straddling the Northamptonshire-Buckinghamshire boundary and previously falling within the royal forest of Whittlewood. This work was undertaken between 2000 and 2005 as part of an AHRC (formerly ARHB-funded research project. This enquiry, and the use it has made of the comparative method, has pinpointed moments of village and hamlet 'creation' and the alternative forms that these could take in their earliest phases. The subsequent development of these settlements has been charted, revealing the divergent paths they took towards the nucleated or dispersed plans they present when first mapped in the 17th, 18th or 19th centuries. This dynamic pattern of settlement has been set against a background of related changes to the authoritative landscape, which saw the fission and fusion of administrative units; to the economic landscape, which witnessed the development of the open field system and the re-organisation of woodland; and to social and cultural landscapes, affected inter alia by the growth and decline of population, and the imposition of Forest Law. The reconstruction of these medieval village territories has only been achieved by adopting an interdisciplinary

Nuevos datos sobre el uso de materia colorante durante el Neolítico antiguo en las comarcas centrales valencianas

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Pablo García Borja

2006-01-01

Full Text Available La caracterización mineralógica de materias colorantes procedentes de los yacimientos valencianos de la Cova de l'Or, la Cova de la Sarna y la Cova Fosca de la Vall d'Ebo demuestra el uso de dos tipos de materia colorante durante el Neolítico Antiguo: Hematites y Cinabrio. Las características y distribución geográfica de cada una de ellas nos remiten a dos estrategias distintas de obtención y. probablemente. de utilización de las mismas.

Medical Business Ethics in the XXI century; Deontologia medica del siglo XXI

Energy Technology Data Exchange (ETDEWEB)

Moya Pueyo, V.

2009-07-01

Since ancient times the medical professional practice included moral rules in order to assure a correct approach of capital problems. These rules evolve and are now gathered in the Deontological Codes watching the Constitution and other higher Laws. There has been an increase of interest for none strictly clinical matter since the appearance of the term Bioethics. The book Deontologia medica en el siglo XXI tackles problems of first interest in the present times, thru statistics and analysis, trying to help the medical doctors that have to take ethic decisions. (Author)

Crossdressing medieval troubadours, Castile to Brazil : Cristóbal de Castillejo (d. 1550) and Augusto de Campos (b. 1931)

OpenAIRE

Roy Rosenstein

2014-01-01

Starting out from a reading of Cristóbal de Castillejo's sixteenth-century sonnet referencing the medieval Occitan troubadours, "Garcilaso y Boscán, siendo llegados", this article reflects on cultural and temporal translations of medieval troubadour lyric. In the second part, it examines in more detail Augusto de Campos's modern Brazilian translations or "transcreations" of Arnaut Daniel's works – the only complete poetic translation in any language of his works.

Homoeopathy in the management of Dyslipidemia: A short review

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Rupali D Bhalerao

2015-01-01

Full Text Available The importance of high serum total cholesterol and high level of low-density lipoprotein cholesterol, as a risk factor for coronary artery diseases is well established. Statin is the first-line of treatment for dyslipidemia and there are known side effects of statin therapy. This study reviews the existing information available in Homoeopathy (research and traditional knowledge for managing dyslipidemia. No rigid inclusion has been kept due to scarcity of evidence-based literature. Preclinical and clinical studies (case records to controlled trials are included. A comprehensive search from major biomedical databases including National Medical Library (PubMed, AYUSH PORTAL, EMBASE, and the Cochrane Library was conducted using the search term “dyslipidemia,” “atherosclerosis,” “arteriosclerosis,” “atheroma” along with “Homoeopathy.” In addition, efforts were made to search authoritative texts of authors, such homoeopathic Materia Medica, repertory, etc. Relevant research was categorized by study type and appraised according to study type and design. Four preclinical, three observational studies, and two case records were identified. From literary search, medicines commonly used in Materia Medica and drugs of Indian origin were noted. There are positive leads in managing patients suffering from dyslipidemia. However, more well-designed studies are warranted to generate effectiveness/efficacy of Homoeopathy.

Some considerations on X-ray fluorescence use in museum measurements - The case of medieval silver coins

International Nuclear Information System (INIS)

Constantinescu, B.; Bugoi, R.; Oberlaender-Tarnoveanu, E.; Parvan, K.

2005-01-01

The purpose of this paper is to give a general layout for the potential applications of Energy-Dispersive X-Ray Fluorescence (ED-XRF) technique for ancient silver coin characterization, using in-situ (in museums) measurements. Examples concerning originality testing, provenance (mines, workshops) identification, counterfeits selection, historical studies (manufacturing technologies, commercial, military and political relationships) are given. Two study cases of medieval coins are described: German brakteaten pfennige and Moldavian groschen. Other analysis methods and their use in the study of medieval coins are illustrated with the example of Particle Induced X-ray Emission (PIXE) technique. (authors)

Diet and diversity at later medieval Fishergate: the isotopic evidence.

Science.gov (United States)

Müldner, Gundula; Richards, Michael P

2007-10-01

We present the results of stable carbon and nitrogen isotope analysis of bone collagen for 155 individuals buried at the Later Medieval (13th to early 16th century AD) Gilbertine priory of St. Andrew, Fishergate in the city of York (UK). The data show significant variation in the consumption of marine foods between males and females as well as between individuals buried in different areas of the priory. Specifically, individuals from the crossing of the church and the cloister garth had consumed significantly less marine protein than those from other locations. Isotope data for four individuals diagnosed with diffuse idiopathic skeletal hyperostosis (DISH) are consistent with a diet rich in animal protein. We also observe that isotopic signals of individuals with perimortem sharp force trauma are unusual in the context of the Fishergate dataset. We discuss possible explanations for these patterns and suggest that there may have been a specialist hospital or a local tradition of burying victims of violent conflict at the priory. The results demonstrate how the integration of archaeological, osteological, and isotopic data can provide novel information about Medieval burial and society. (c) 2007 Wiley-Liss, Inc.

Disputing strategies in medieval Scandinavia

DEFF Research Database (Denmark)

Orning, Hans Jacob

In Scandinavia the study of disputes is still a relatively new topic: The papers offered here discuss how conflicts were handled in Scandinavian societies in the Middle Ages before the emergence of strong centralized states. What strategies did people use to contest power, property, rights, honour......, and other kinds of material or symbolic assets? Seven essays by Scandinavian scholars are supplemented by contributions from Stephen White, John Hudson and Gerd Althoff, to provide a new baseline for discussing both the strategies pursued in the political game and those used to settle local disputes. Using...... practice and process as key analytical concepts, these authors explore formal law and litigation in conjunction with non-formal legal proceedings such as out-of-court mediation, rituals, emotional posturing, and feuding. Their insights place the Northern medieval world in a European context of dispute...

Harris lines of the tibia across centuries: a comparison of two populations, medieval and contemporary in Central Europe

International Nuclear Information System (INIS)

Ameen, S.; Vock, P.; Anderson, S.E.; Staub, L.; Ulrich, S.; Ballmer, F.

2005-01-01

To determine the incidence of Harris lines in two medieval populations which inhabited the Canton of Berne, in Central Switzerland, and to compare the results with those of a contemporary population living in the same geographical area. A simplified method is described for measuring the age of the individual at the time of formation of Harris lines, with possible future applications. Radiographs of 112 well-preserved tibiae of skeletons of two medieval populations from the eighth to fifteenth centuries were reviewed for the incidence of Harris lines. The results were compared with those of 138 current patients living in the same geographic location in Central Switzerland. Age and gender of the medieval individual were determined using known anthropological methods. Age of bone at the time of formation of Harris lines was estimated according to the method of Maat. Harris lines were found in 88 of 112 (80%) of the examined medieval skeletons and in 28 of 138 (20%) of the living individuals. Higher incidences of Harris lines were found at the age of 2 years and at ages between 8 and 12 years in both populations. No gender difference was found regarding the incidence of Harris lines. In both populations the occurrence of Harris lines was associated with certain diseases such as degenerative bone disease, trauma, osteoporosis, rheumatoid arthritis, peripheral vascular diseases, rickets and bony deformities. (orig.)

Harris lines of the tibia across centuries: a comparison of two populations, medieval and contemporary in Central Europe

Energy Technology Data Exchange (ETDEWEB)

Ameen, S.; Vock, P.; Anderson, S.E. [University Hospital of Bern, Department of Diagnostic Radiology, Bern (Switzerland); Staub, L.; Ulrich, S. [University of Bern, Institute of Historical Medicine, Bern (Switzerland); Ballmer, F. [University Hospital of Bern, Department of Orthopaedics, Bern (Switzerland)

2005-05-01

To determine the incidence of Harris lines in two medieval populations which inhabited the Canton of Berne, in Central Switzerland, and to compare the results with those of a contemporary population living in the same geographical area. A simplified method is described for measuring the age of the individual at the time of formation of Harris lines, with possible future applications. Radiographs of 112 well-preserved tibiae of skeletons of two medieval populations from the eighth to fifteenth centuries were reviewed for the incidence of Harris lines. The results were compared with those of 138 current patients living in the same geographic location in Central Switzerland. Age and gender of the medieval individual were determined using known anthropological methods. Age of bone at the time of formation of Harris lines was estimated according to the method of Maat. Harris lines were found in 88 of 112 (80%) of the examined medieval skeletons and in 28 of 138 (20%) of the living individuals. Higher incidences of Harris lines were found at the age of 2 years and at ages between 8 and 12 years in both populations. No gender difference was found regarding the incidence of Harris lines. In both populations the occurrence of Harris lines was associated with certain diseases such as degenerative bone disease, trauma, osteoporosis, rheumatoid arthritis, peripheral vascular diseases, rickets and bony deformities. (orig.)

Materia y Pobreza = Matter and Poverty

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María Teresa Muñoz

2013-10-01

Full Text Available ResumenLa acumulación material es uno de los signos más identificables de la pobreza. El pobre vive apegado a la tierra, esa es su única posesión y a partir de ella construirá sus refugios, sus habitaciones, sus utensilios. Las construcciones de arcilla, de barro, moldeadas con gran abundancia de materia  se encuentran en los poblados primitivos, pero cualquier situación marcada por la extrema pobreza lo estará también por las acumulaciones de material. Resulta inimaginable una situación de pobreza que no implique la acumulación de materia y esto es particularmente evidente en las sociedades desarrolladas, donde un mendigo es reconocible por su montaña de ropas, calzado o enseres de todo tipo.Resulta, sin embargo, significativo que en los discursos de los ideólogos de la modernidad, la identificación de ésta con el advenimiento de una sociedad sin clases venga acompañada de una apelación a la pobreza, una nueva pobreza fría y sobria, propia de una habitación humana abierta y transparente, casi desnuda, e igualitaria para todos los hombres sin distinción de clases sociales. Así, la pobreza moderna estaría ligada al material, a los nuevos materiales, pero no es una condición impuesta, sino elegida, o al menos aceptada como inevitable por el nuevo hombre.La convivencia entre una pobreza de la acumulación material y una pobreza de ascetismo y renuncia es un hecho tanto en los discursos como en las obras de las vanguardias del siglo XX. La acumulación de materia informe y trabajada manualmente tiene lugar al mismo tiempo que la exhibición de la desnudez y la frialdad de los materiales producidos por la industria.  Y en ambos casos, se apela a la pobreza como última referencia para las obras que tratan de ser una expresión fiel de las aspiraciones de su época.Palabras clavemateria, pobreza, material, acumulación, modernidad, sociedadAbstractAccumulation of matter is one of the most recognizable signs of poverty. The poor

Bacteriological evaluation of Allium sativum oil as a new medicament for pulpotomy of primary teeth.

Science.gov (United States)

Mohammad, Shukry Gamal; Baroudi, Kusai

2015-01-01

To compare the effects of Allium sativum oil and formocresol on the pulp tissue of the pulpotomized teeth. Twenty children were selected for this study. All children had a pair of non-vital primary molars. A sterile paper point was dipped in the root canals prior to the mortal pulpotomy. These paper points were collected in transfer media and immediately transported to the microbiological lab to be investigated microbiologically (for Streptococcus mutans and Lactobacillus acidophilus). Then the procedure of mortal pulpotomy was performed. After 2 weeks, the cotton pellets were removed and sterile paper points were dipped in the root canals for microbiological examination. Then comparison between the count of bacteria before and after treatment was conducted. Statistical analysis was performed using independent t-test and paired t-test at the significance level of α = 0.05. After application of both medicaments, there was a marked decrease in S. mutans and L. acidophilus counts. The difference between the mean of log values of the count before and after the application was highly significant for both medicaments (P sativum oil was used. A. sativum oil had more powerful antimicrobial effects than formocresol on the bacteria of the infected root canals.

The role of medicaments, exosomes and miRNA molecules in modulation of macrophage immune activity

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Katarzyna Nazimek

2015-01-01

Full Text Available Macrophages play an important role in innate immunity, in induction and orchestration of acquired immune response as well as in the maintenance of tissue homeostasis. Macrophages as antigen presenting cells induce or inhibit the development of immune response and as effector cells play an important role in innate immunity to infectious agents and in delayed--type hypersensitivity as well. Thus, either up- or down-regulation of their activity leads to the impairment of different biological processes. This often results in the development of immunological diseases or inflammatory response associated with metabolic, cardiovascular or neuroendocrine disorders. Therefore, the possibility of modulation of macrophage function should allow for elaboration of new effective therapeutic strategies. Noteworthy, interaction of medicaments with macrophages may directly mediate their therapeutic activity or is an additional beneficial effect increasing efficacy of treatment. Further, macrophage differentiation is regulated by miRNA-223, while expression of miRNA-146 and miRNA-155 may modulate and/or be a result of the current cell phenotype. Present review is focused on the current knowledge about the action of medicaments, microRNA molecules, exosomes and related vesicles on macrophages leading to modulation of their biological activity.

Archaeometrical studies on medieval silver coins at the Bucharest TANDEM Accelerator

International Nuclear Information System (INIS)

Bugoi, R.; Constantin, F.; Constantinescu, B.; Oberlaender-Tarnoveanu, E.; Parvan, K.

2003-01-01

An extensive study on Medieval Moldavian (XIVth - XVIth Centuries) silver coins (Groschen) using 3 MeV protons PIXE (Proton Induced X-ray Emission) and '2 41 Am source based XRF (X-Ray Fluorescence) was performed in order to determine the evolution of the coinage (debasement, metal sources, minting technologies). XRF was used to determine heavier elements concentrations. Comparing the trace elements results (Bi, Pb, Zn, Au) obtained on these samples with the ones on coins from Hungary, Poland, Tatar Khanate, Bohemia we bring support to the curator hypothesis that a lot of Moldavian emissions were made by melting foreign coins, possibly obtained as customs taxes or from trade with these neighbouring countries. For the late medieval silver coins, the high Hg content may be an indication of an imperfect metallurgical processing of the local silver ores. The relationship between the silver content of the coins and the military conflicts corresponding to the minting periods is discussed, taking into account the fact that crisis times are characterized by a decrease in the precious metal concentration. (authors)

Archaeometrical studies on medieval silver coins at the Bucharest Tandem Accelerator

International Nuclear Information System (INIS)

Bugoi, Roxana; Constantin, Florin; Constantinescu, Bogdan

2005-01-01

An extensive study on Medieval Moldavian (XIVth - XVIth Centuries) silver coins (groschen) using 3 MeV protons PIXE (Proton Induced X-ray Emission) and 241 Am source based XRF (X-Ray Fluorescence) was performed in order to determine the evolution of the coinage (debasement, metal sources, minting technologies). XRF was used to determine the heavier elements concentrations. Comparing the trace element results (Bi, Pb, Zn, Au) obtained on these samples with the ones on coins from Hungary, Poland, Tatar Khanate, Bohemia, we bring support to the curator hypothesis that a lot of Moldavian emissions were made by melting foreign coins, possibly obtained as customs taxes or from trade with these neighbouring countries. For the late medieval silver coins, the high Hg content may be an indication of an imperfect metallurgical processing of the local silver ores. The relationship between the silver content of the coins and the military conflicts corresponding to the minting periods is discussed, taking into account the fact that crisis times are characterized by a decrease in the precious metal concentration. (authors)

The use of geothermal energy at a chieftan's farm in medieval Iceland

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Gudrun Sveinbjarnardottir

2003-10-01

Full Text Available Archaeological investigations at the farm site of Reykholt, in the Reykholtsdalur valley in western Iceland (Fig. 1 , have produced evidence of sophisticated use of geothermal energy in the medieval period that is unmatched by comparable finds elsewhere in this geothermally and volcanically active country.

Two incrusted medieval swords from Zbaszyn, Lubusz voivodship

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Głosek, Marian

2007-12-01

Full Text Available This paper presents two interesting medieval swords that can be dated between the end of the 12th century to the beginning of the 14th century AD. Both display, engraved in the fuller, inscriptions in silver and copper inlay, one of them a Latin text, the other heraldic symbols.

Se presentan dos espadas medievales fechables entre finales del S. XII y principios del XIV, decoradas con damasquinados en plata y aleación de cobre. Una presenta un texto latino y mativos ornamentales; la otra, elementos heráldicos.

XRF and UV-Vis-NIR analyses of medieval wall paintings of al-Qarawiyyin Mosque (Morocco)

Science.gov (United States)

Fikri, I.; El Amraoui, M.; Haddad, M.; Ettahiri, A. S.; Bellot-Gurlet, L.; Falguères, C.; Lebon, M.; Nespoulet, R.; Ait Lyazidi, S.; Bejjit, L.

2018-05-01

Medieval wall painting fragments, taken at the medieval Mosque of al-Qarawiyyin in Fez, have been investigated by means of X-ray fluorescence and UV-Vis-NIR diffuse reflectance spectroscopies. The analyses permitted to determine the palette of pigments used by craftsmen of the time. Hematite or red ochre were used to obtain red brown colours, calcite for white, copper-based pigments for blue and blue-grey shades while a mixture of cinnabar, lead-based pigments and hematite was adopted to make red-orange colours. Furthermore, the analysis of mortars (external layer and plaster) on these wall painting samples revealed that they are composed mainly by calcite and sometimes by additional compounds such as quartz and gypsum.

Soluciones concluidas en el MERCOSUR en materia de jurisdicción internacional: Análisis de los protocolos de Buenos Aires sobre jurisdicción internacional en materia contractual y de San Luis en materia de resp. civil emergente de accidentes de tránsito

Directory of Open Access Journals (Sweden)

Eduardo Tellechea Bergman

2015-10-01

Full Text Available Contenido: Precisiones.  La jurisdicción en las relaciones privadas internacionales en el MERCOSUR. Necesidad de una regulación común a todos los estados parte. Protocolo de Buenos Aires sobre jurisdicción internacional en materia contractual. Protocolo de San Luis sobre responsabilidad civil emergente de accidentes de tránsito

Becoming Artifacts Medieval Seals, Passports and the Future of Digital Identity

Science.gov (United States)

Chango, Mawaki

2012-01-01

What does a digital identity token have to do with medieval seals? Is the history of passports of any use for enabling the discovery of Internet users' identity when crossing virtual domain boundaries during their digital browsing and transactions? The agility of the Internet architecture and its simplicity of use have been the engines of its…

Solidarity and Brotherhood in Medieval Italian Confraternities: AWay of Inclusion or Exclusion? Solidarity and Brotherhood in Medieval Italian Confraternities: A Way of Inclusion or Exclusion?

Directory of Open Access Journals (Sweden)

Marina Gazzini

2012-10-01

Full Text Available

Historians usually consider medieval confraternities as lay religious communities involved in devotional and charitable practices which carried out a socializing function as well. Confraternities, when seen through this lens, fundamentally appear to be inclusive communities which helped strengthen the identities of good believers and good citizens by focusing on the solidarity created among the members of the association itself. This ecumenical vision depends essentially on a positive prejudice which is automatically ascribed to the concept of solidarity, and which often leads one to forget that, though solidarity in some cases may have rationales for inclusion, in many others it can be a source of exclusion. Yet, these opposite characteristics only seem to conflict, because to exclude someone means including someone else at the same time. The aim of this short paper is to discuss these aspects, especially with respect to northern late medieval Italy, along the lines of the question posed in these preliminary remarks: were medieval confraternities inclusive communities or exclusive institutions?

Gli studi sulle confraternite medievali, oltre che agli aspetti devozionali e caritativi, sono soliti guardare alle finalità solidaristiche e inclusive di tali associazioni. E, a proposito di queste ultime, la solidarietà che si instaurava all’interno del gruppo confraternale, e fra questo e quella parte della popolazione destinataria di solidarietà e assistenza, spirituale come materiale, viene vista come funzionale al rafforzamento del ruolo e dell’identità di buon cittadino (o buon suddito e di buon fedele. Un pregiudizio positivo grava però sul concetto di solidarietà: se vi sono solidarietà che includono, ne esistono tuttavia altre che escludono. Una confraternita infatti prevedeva spazi chiusi di azione, fisici e metaforici, tali da escludere chi se ne trovava al di fuori. Sulla base di esemplificazioni relative all’Italia del

Embroided Portraits in the Romanian Medieval Art

Directory of Open Access Journals (Sweden)

Ecaterina Marghidan

2015-05-01

Full Text Available If the artistic value of the Romanian medieval embroidery is obvious, it is no less real its documentary value. Most embroided portraits are made on liturgical pieces and they are a proof of the relationship of the rulers with the Orthodox Church. The position of the characters is a mute way of communicating the status that the voievod had. The vertical rigid representations, kneeling, the gestures of the palms and elbows, the beneficence objects, the way characters are grouped, the proportion or their placement in the work can be symbolically interpreted depending on the type of the Liturgical item on which the embroidery was done.

In praise of death : history and poetry in medieval Marwar (South Asia)

NARCIS (Netherlands)

Kamphorst, Janet

2008-01-01

This study of heroic and epic “war poetry” transmitted by the poets of pastoral-nomadic communities in medieval Marwar (Rajasthan) evokes the lived past of the Rajput, Bhil and Charan of the Marwari desert with a detailed analysis of poetic sources concerning Pabuji, a fourteenth-century warrior and

Optical spectroscopy applied to the analysis of medieval and post-medieval plain flat glass fragments excavated in Belgium

Science.gov (United States)

Meulebroeck, W.; Wouters, H.; Baert, K.; Ceglia, A.; Terryn, H.; Nys, K.; Thienpont, H.

2010-04-01

Window glass fragments from four Belgian sites were studied and for a set of eighty-five samples the UV-VIS-NIR transmission spectra were analyzed. This collection contains historical and archaeological finds originating from religious buildings namely the Basilica of Our Lady of Hanswijk in Mechelen (17th-20thc) and the Church of Our Lady in Bruges (16th-20thc) as well as from secular buildings as a private house/Antwerp (18th-1948) and the castle of Middelburg-in-Flanders (1448-17thc). All sites contain material on the hinge point between the medieval and the industrial tradition. The variation in composition of the analyzed samples can be explained by the use of different glassmaking recipes, more specifically the use of different raw materials. The composition of window glass differs essentially in the type of flux, using a potash rich fluxing agent until the post-medieval times and industrial soda from the 19th century onwards. A second difference concerns the iron impurities in the glass. For all fragments a clear compositional classification could be made based on the iron concentration. These conclusions were based on archaeological research and drawn after submitting samples to expensive, complex, time-consuming and destructive chemical analyzing methods. Our study indicates that similar conclusions could be made applying the proposed optical based methodology for plain window glass. As a whole, the obtained results make it possible to cluster the fragments for a particular site based on three different sensing parameters: the UV absorption edge, the color and the presence of characteristic absorption bands. This information helps in identifying trends to date window glass collections and indicating the use of different raw materials, production technologies and/or provenance.

Studies of beneficial interactions between active medicaments and excipients in pharmaceutical formulations.

Science.gov (United States)

Kalinkova, G N

1999-09-30

A review of "up to date" research findings leading to new concepts of the pharmaceutical formulations and their interactions has been presented. The rational approaches to the excipients choice as well as to their interactions with medicaments have been shown as a basis for modern modelling of pharmaceutical formulations. The importance of complexation, hydrogen bonding, ion-dipole, dipole-dipole and van der Waals attractions as the tools which can modify the physicochemical, pharmacological or pharmacokinetical behaviour of the medicaments has been emphasised. In vivo studies (carried out in healthy human subjects-volunteers, in beagle dogs, in rats etc.) and in vitro studies (on excised human skin, hairless mouse skin etc.) as well as studies of chemical stability and bioavailability serve also as a proof of these interactions. Therefore, excipients are important components of pharmaceutical formulations and they can take an active part in the improvement of the characteristics of formulations (but they may also reduce the effectiveness of some preparations). In this context, the so called active and inactive ingredients in pharmaceutical formulations are inexact, old and "out-of date". Their further use is only conventional. In conclusion, among the various modern techniques applied the combination of infrared spectroscopy and X-ray diffraction has been estimated as the most successful in proving the interactions between drugs and excipients. Finally, pharmaceutical formulations and their interactions have constituted a diverse and rapidly expanding field of Pharmacy (Pharmaceutical Technology, Pharmaceutical Industry and Pharmaceutical Sciences) which covers a wide range of numerical topics within an unified framework.

Un suelo referible al periodo calido medieval en Patagonia Austral y Tierra del Fuego (Argentina. Aspectos cronologicos y paleoclimaticos

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Favier Dubois, C. M.

2002-08-01

Full Text Available Geoarchaeological work done in Southernmost Patagonia and in the north of Tierra del Fuego, have revealed the recurrent presence of a paedogenesis interval represented by a soil of an A-AC-C profile, with a mollic epipedon, in the upper section of eolian and colluvial deposits of the late Holocene. This soil is today buried in the sites that have been analyzed, while it remains exposed in other areas of the landscape. Radiocarbon dates obtained on materials placed below it (maximum ages and those obtained by OCR (Oxidizable Carbon Ratio in the AC horizon of this soil (minimum ages, indicate the beginning of its development around the year 1000 BP. Its chronology and environmental implications suggest a relationship with the medieval climatic fluctuations called Medieval Warm Period or Medieval Optimum in Europe. This period has correlates detected in Patagonia by dendroclimatic studies.Estudios geoarqueológicos realizados en 5 localidades de Patagonia austral y norte Tierra del Fuego han revelado la recurrente presencia de un suelo de perfil A-AC-C, de epipedon mólico, en depósitos eólicos y coluviales del Holoceno tardío. Este suelo se observa sepultado en los yacimientos arqueológicos analizados, mientras que permanece expuesto en otras posiciones del paisaje. Numerosas edades máximas y mínimas obtenidas por 14C y por la técnica de OCR (Oxidizable Carbon Ratio indican el comienzo de su desarrollo hacia el 1000 AP. Su cronología e implicancias ambientales permiten vincularlo con fluctuaciones climáticas desarrolladas durante el denominado Período Cálido Medieval u Optimo Medieval Europeo, con correlatos detectados en Patagonia a través de estudios dendroclimáticos.

Waste Management and Attitudes Towards Cleanliness in Medieval Central Europe

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Havlíček Filip

2017-12-01

Full Text Available The paper deals with the relationships between people and waste in the Middle Ages, primarily in urban environments in Central Europe. At the center of interest are the attitudes of the inhabitants of medieval cities towards cleanliness and a description of different waste management practices. This paper also describes an experiment using ashes to launder clothing as one possible use of a particular waste material.

Material Culture and Diasporic Experiences: A Case of Medieval Hanse Merchantsin the Baltic

DEFF Research Database (Denmark)

Naum, Magdalena

2015-01-01

The Hanseatic League, a late medieval merchant association with roots in northern German towns, is credited with the establishment of extensive economic and geographic connections and considerable impact on the development of urban culture around the Baltic and the North Sea. Its merchants...

Cranial vault trauma and selective mortality in medieval to early modern Denmark

DEFF Research Database (Denmark)

Boldsen, Jesper L; Milner, George R; Weise, Svenja

2015-01-01

to interpersonal violence in past populations. Three medieval to early modern Danish skeletal samples are used to estimate the effect of selective mortality on males with cranial vault injuries who survived long enough for bones to heal. The risk of dying for these men was 6.2 times higher than...

Auditory Ossicles in Archaeological Skeletal Material from Medieval Denmark

DEFF Research Database (Denmark)

Qvist, M; Grøntved, A M

2000-01-01

Auditory ossicles were collected from two skeletal materials from early medieval Denmark. A total of 147 and 1,162 ossicles were obtained from the 2 materials, constituting 23% and 55% of the possible in vivo ossicles. The numbers and percentages found are among the highest reported from studies...... of archaeological skeletal material. Archaeological ossicles may be used in palaeopathological evaluation of chronic otitis media and otosclerosis, and morphometric studies of the ossicles might be valuable in analysis of population genetics and taxonomy....

La tradición medieval prearistotélica y la formación de la politica como teoría a partir de 1265

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Francisco Bertelloni

2013-11-01

Full Text Available The paper deals with the gradual constitution of the politica as theory in the middle ages within the division of the philosophiamoralis in ethica, oeconomica and politica. The author organizes the paper in three parts in accordance with three different stages of medieval treatment of the politica as science. First he gives an overview of the medieval notion of politica until the first half of the thirteenth century. Secondly he analyzes Albert's conception of politica in the treatise Super Ethica. Thirdly he shows Albert's modifications of his own conception after the medieval reception of Aristotle's Politics.

On the threshold of adulthood: A new approach for the use of maturation indicators to assess puberty in adolescents from medieval England.

Science.gov (United States)

Lewis, Mary; Shapland, Fiona; Watts, Rebecca

2016-01-01

This study provides the first large scale analysis of the age at which adolescents in medieval England entered and completed the pubertal growth spurt. This new method has implications for expanding our knowledge of adolescent maturation across different time periods and regions. In total, 994 adolescent skeletons (10-25 years) from four urban sites in medieval England (AD 900-1550) were analyzed for evidence of pubertal stage using new osteological techniques developed from the clinical literature (i.e., hamate hook development, cervical vertebral maturation (CVM), canine mineralization, iliac crest ossification, and radial fusion). Adolescents began puberty at a similar age to modern children at around 10-12 years, but the onset of menarche in girls was delayed by up to 3 years, occurring around 15 for most in the study sample and 17 years for females living in London. Modern European males usually complete their maturation by 16-18 years; medieval males took longer with the deceleration stage of the growth spurt extending as late as 21 years. This research provides the first attempt to directly assess the age of pubertal development in adolescents during the 10th-17th centuries. Poor diet, infections, and physical exertion may have contributed to delayed development in the medieval adolescents, particularly for those living in the city of London. This study sheds new light on the nature of adolescence in the medieval period, highlighting an extended period of physical and social transition. © 2015 Wiley Periodicals, Inc.

Diagramas de energía, fuerza y materia = Diagrams of energy, force and matter

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Josep Maria Montaner

2013-10-01

Full Text Available ResumenEn este ensayo se va a tratar sobre arquitectura a partir de la definición de forma como “estructura esencial e interna, como construcción del espacio y de la materia”. Para ello, podemos establecer, como punto de partida, que el proceso de la arquitectura va de la energía, las fuerzas y la materia hacia la forma. Por tanto, teorizar sobre la forma en arquitectura nos lleva a reflexionar sobre tres fenómenos previos a su configuración: la energía, las fuerzas y la materia. Para seguir estos procesos físicos es útil remitirse al pensamiento postestructuralista de Gilles Deleuze y Félix Guattari, especialmente a su texto Mil Mesetas. Capitalismo y esquizofrenia (1980 y a conceptos como “rizoma” y “agenciamiento” y, sobre todo, utilizar la herramienta interpretativa y creativa del “diagrama”.Palabras claveenergía, fuerza, materia, forma, Deleuze, GuattariAbstractThis essay will deal on architecture from the defi nition of form as "critical and internal structure  as construction of space and matter." For that, we can establish, as a starting point, that the process of architecture goes from energy, forces and matter to form. Thus, theorizing about form in architecture leads us to refl ect on three prior phenomena to its confi guration: energy, forces and matter. To follow these physical processes is useful to refer the poststructuralist thought´s Gilles Deleuze and Felix Guattari, especially his text A Thousand Plateaus. Capitalism and Schizophrenia (1980 and concepts such as "rhizome" and "assemblage" and, above all, to use the creative and interpretative tool of "diagramme".Key wordsenergy, force, matter, form, Deleuze, Guattari

Medieval emergence of sweet melons, Cucumis melo (Cucurbitaceae).

Science.gov (United States)

Paris, Harry S; Amar, Zohar; Lev, Efraim

2012-07-01

Sweet melons, Cucumis melo, are a widely grown and highly prized crop. While melons were familiar in antiquity, they were grown mostly for use of the young fruits, which are similar in appearance and taste to cucumbers, C. sativus. The time and place of emergence of sweet melons is obscure, but they are generally thought to have reached Europe from the east near the end of the 15th century. The objective of the present work was to determine where and when truly sweet melons were first developed. Given their large size and sweetness, melons are often confounded with watermelons, Citrullus lanatus, so a list was prepared of the characteristics distinguishing between them. An extensive search of literature from the Roman and medieval periods was conducted and the findings were considered in their context against this list and particularly in regard to the use of the word 'melon' and of adjectives for sweetness and colour. Medieval lexicographies and an illustrated Arabic translation of Dioscorides' herbal suggest that sweet melons were present in Central Asia in the mid-9th century. A travelogue description indicates the presence of sweet melons in Khorasan and Persia by the mid-10th century. Agricultural literature from Andalusia documents the growing of sweet melons, evidently casabas (Inodorous Group), there by the second half of the 11th century, which probably arrived from Central Asia as a consequence of Islamic conquest, trade and agricultural development. Climate and geopolitical boundaries were the likely causes of the delay in the spread of sweet melons into the rest of Europe.

Actively Engaging Students in Culture, Gender, and Class Issues in Medieval Literature

Science.gov (United States)

Donnelly, Colleen E.

2017-01-01

Students often find it difficult to understand literature of another era and a world that differs from their own. From interacting with illuminated manuscript pages to conducting a mock trial, this article discusses ways in which visual and active learning techniques can be used to engage students in medieval literature and culture.

LAS RELACIONES ENTRE LOS TRIBUNALES INTERNACIONALES Y LOS TRIBUNALES NACIONALES EN MATERIA DE DERECHOS HUMANOS: EXPERIENCIAS EN LATINOAMÉRICA

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Néstor P. Sagüés

2003-01-01

Full Text Available El autor analiza la relación entre los tribunales nacionales e internacionales o supranacionales con competencia jurisdiccional vinculante en materia de derechos humanos, considerando la existencia de tres posiciones en la materia: la posición conflictual de la declaración de inejecutabilidad, la posición del seguimiento nacional y la del margen de apreciación.The author analyzes the relationship between national and international or supranational courts with binding jurisdiction over matters of human rights, reviewing three positions in this subject: the conflict perspective of declaration of non-executability, the position of national follow-up, and the doctrine of margin of appreciation.

Medieval iconography of watermelons in Mediterranean Europe

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Paris, Harry S.; Daunay, Marie-Christine; Janick, Jules

2013-01-01

Background and Aims The watermelon, Citrullus lanatus (Cucurbitaceae), is an important fruit vegetable in the warmer regions of the world. Watermelons were illustrated in Mediterranean Antiquity, but not as frequently as some other cucurbits. Little is known concerning the watermelons of Mediterranean Europe during medieval times. With the objective of obtaining an improved understanding of watermelon history and diversity in this region, medieval drawings purportedly of watermelons were collected, examined and compared for originality, detail and accuracy. Findings The oldest manuscript found that contains an accurate, informative image of watermelon is the Tractatus de herbis, British Library ms. Egerton 747, which was produced in southern Italy, around the year 1300. A dozen more original illustrations were found, most of them from Italy, produced during the ensuing two centuries that can be positively identified as watermelon. In most herbal-type manuscripts, the foliage is depicted realistically, the plants shown as having long internodes, alternate leaves with pinnatifid leaf laminae, and the fruits are small, round and striped. The manuscript that contains the most detailed and accurate image of watermelon is the Carrara Herbal, British Library ms. Egerton 2020. In the agriculture-based manuscripts, the foliage, if depicted, is not accurate, but variation in the size, shape and coloration of the fruits is evident. Both red-flesh and white-flesh watermelons are illustrated, corresponding to the typical sweet dessert watermelons so common today and the insipid citron watermelons, respectively. The variation in watermelon fruit size, shape and coloration depicted in the illustrations indicates that at least six cultivars of watermelon are represented, three of which probably had red, sweet flesh and three of which appear to have been citrons. Evidently, citron watermelons were more common in Mediterranean Europe in the past than they are today. PMID:23904443

RESENHA: BROADIE, A. Introduction to medieval logic. Segunda edição. Oxford: Clarendon Press, 2002.

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Alexandre Cabeceiras

2011-05-01

Full Text Available Nessa obra, Broadie, após discutir qual seria a melhor ordem de exposição paraum texto sobre lógica medieval, decide tratar primeiro dos termos, depois dasproposições e, por fim, das inferências. Mas, não se restringindo ao que era uniforme oupredominante na Idade Média, explora disputas envolvendo lógicos ou filósofos daqueleperíodo. Delimitando seu objeto, estabelece que a obra lidará, hegemonicamente, commaterial produzido no período entre a segunda metade do século XIII e o final do séculoXV, por considerar essa a fase mais produtiva no que se refere à lógica medieval.

Finger printing of medieval investment cast idols by radiography

International Nuclear Information System (INIS)

Venkatraman, B.; Babu Rao, C.; Bhattacharya, D.K.; Raj, Baldev

1993-01-01

Among the various methods, radiography is an important technique that can be used to fingerprint an idol. This is because, these idols are cast structures, and radiography is the most reliable technique for the detection of internal features like casting defects. This paper presents the radiographic methodology adopted and the results of the studies to characterise radiographically three medieval cast idols belonging to different periods 9th, 13th, and 16th century obtained from the government museum Madras. (author). 2 refs., 1 fig., 2 tabs

Conservation of a medieval climbing stem by freeze-drying and resin impregnation

International Nuclear Information System (INIS)

Schaudy, R.; Slais, E.; Eibner, C.

1985-12-01

The conservation of a climbing stem originating from a medieval mining adit is described. The fragile wet object was preserved by a combined process consisting of freeze-drying after a polyethylene glycol bath and consecutive resin impregnation with curing by gamma irradiation. The whole conservation process took 1 year. The result is discussed. (Author)

Enseñando el oficio antropológico: prácticas pre profesionales en la materia Antropología Sociocultural II

OpenAIRE

Brunatti, Olga; Chaves, Mariana; Cremonesi, Mariel; Hanlon, Paula; Lago, Gabriela; Mora, Ana Sabrina

2016-01-01

En esta presentación compartiremos la experiencia de una propuesta de enseñanzaaprendizaje en el marco de la materia Antropología Sociocultural II de la Facultad de Ciencias Naturales y Museo de la Universidad Nacional de La Plata, donde se incorporan prácticas pre-profesionales con trabajo de campo. Estas prácticas comenzaron a implementarse en la cátedra en el año 2013, en el contexto de una serie de cambios en el equipo docente y en el programa general de la materia. En el presente trab...

Red layered medieval stained glass window characterization by means of micro-PIXE technique

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Ortega-Feliu, I., E-mail: iofeliu@us.es [Centro Nacional de Aceleradores, Universidad de Sevilla, Avda. Thomas A. Edison 7, 41092 Sevilla (Spain); Gomez-Tubio, B. [Centro Nacional de Aceleradores, Universidad de Sevilla, Avda. Thomas A. Edison 7, 41092 Sevilla (Spain); Departamento de Fisica Aplicada III, Universidad de Sevilla (Spain); Respaldiza, M.A. [Centro Nacional de Aceleradores, Universidad de Sevilla, Avda. Thomas A. Edison 7, 41092 Sevilla (Spain); Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Sevilla (Spain); Capel, F. [Instituto de Ceramica y Vidrio, Consejo Superior de Investigaciones Cientificas (Spain)

2011-10-15

Red layered medieval stained glass windows on a transparent greenish substrate are characteristic of European medieval cathedrals, but few compositional analyses have been performed on the coloured layers. The PIXE technique has been performed on a red layered stained glass window obtained during the restoration works carried out in Las Huelgas Monastery in Burgos (Spain). Protons of 3 MeV with a beam of 4 x 5 {mu}m{sup 2} were used to acquire elemental maps of a cross section of the sample, in order to observe the homogeneity of the layered structure and its substrate. In our work, copper was detected as in other layered glasses but a correspondence with lower amounts of zinc has also been determined. Both elements appear enriched in the red coloured layers, while the other quantified elements have the same relative composition along the sample. Corrosion layers, due to the lead supporting structure of the window, were also found.

The Medieval Climate Anomaly and Little Ice Age in Chesapeake Bay and the North Atlantic Ocean

Science.gov (United States)

Cronin, T. M.; Hayo, K.; Thunell, R.C.; Dwyer, G.S.; Saenger, C.; Willard, D.A.

2010-01-01

A new 2400-year paleoclimate reconstruction from Chesapeake Bay (CB) (eastern US) was compared to other paleoclimate records in the North Atlantic region to evaluate climate variability during the Medieval Climate Anomaly (MCA) and Little Ice Age (LIA). Using Mg/Ca ratios from ostracodes and oxygen isotopes from benthic foraminifera as proxies for temperature and precipitation-driven estuarine hydrography, results show that warmest temperatures in CB reached 16-17. ??C between 600 and 950. CE (Common Era), centuries before the classic European Medieval Warm Period (950-1100. CE) and peak warming in the Nordic Seas (1000-1400. CE). A series of centennial warm/cool cycles began about 1000. CE with temperature minima of ~. 8 to 9. ??C about 1150, 1350, and 1650-1800. CE, and intervening warm periods (14-15. ??C) centered at 1200, 1400, 1500 and 1600. CE. Precipitation variability in the eastern US included multiple dry intervals from 600 to 1200. CE, which contrasts with wet medieval conditions in the Caribbean. The eastern US experienced a wet LIA between 1650 and 1800. CE when the Caribbean was relatively dry. Comparison of the CB record with other records shows that the MCA and LIA were characterized by regionally asynchronous warming and complex spatial patterns of precipitation, possibly related to ocean-atmosphere processes. ?? 2010.

Environment and Economy of the Early Medieval Settlement in Žatec

Czech Academy of Sciences Publication Activity Database

Kočár, P.; Čech, Petr; Kozáková, Radka; Kočárová, R.

2010-01-01

Roč. 1, 1-2 (2010), s. 45-60 ISSN 1804-848X R&D Projects: GA AV ČR IAA800020706 Institutional research plan: CEZ:AV0Z80020508 Keywords : Žatec * Early Medieval Period * plant macroremains * agriculture * cereals * pollen analysis * charcoal analysis * three field system Subject RIV: AC - Archeology, Anthropology, Ethnology http://www.iansa.eu/papers/IANSA-2010-01-02-kocar.pdf

On the street and in the bathhouse: medieval Galenism in action?

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Coomans, J.

2013-06-01

Full Text Available In this article we combine the perspective of medieval urban hygiene and the fi ndings of medical and intellectual historians by tracing some ways in which medieval urban residents and governments attempted to limit disease and promote health by recourse to preventative measures. In both of the urban regions and domains in focus, namely Italian streets and Dutch bathhouses, considerable thought had been put into reducing the health risks perceived as attending upon them, at times devising arguments and procedures that possibly refl ect insights from prevailing medical theories and the advice of practitioners. We suggest that the relation between medical learning and health practices was more complex than a trickledown process, and analyze them in the context of pre-modern “healthscaping”: a physical, social, legal, administrative, and political process by which urban individuals, groups, and especially governments sought to safeguard and improve collective wellbeing.En este artículo combinamos la perspectiva de la higiene urbana medieval con los hallazgos de los historiadores de la medicina y de la intelectualidad, analizando algunas de las formas con que los habitantes y los gobiernos urbanos medievales intentaron limitar las enfermedades y promover la salud mediante medidas preventivas. En las dos regiones que se toman en consideración (las calles italianas y los baños holandeses, se hizo un esfuerzo de reflexión considerable para reducir los riesgos de la salud, elaborando a veces argumentos y procedimientos que reflejaban las ideas de las teorías médicas imperantes y los consejos de los profesionales. Sugerimos que la relación entre el aprendizaje médico y las prácticas de salud era más compleja que un simple proceso de propagación, y la analizamos en el contexto de la preservación de la salud de carácter pre-moderno: un proceso físico, legal, administrativo y político mediante el cual individuos, grupos y, especialmente

DNA and bone structure preservation in medieval human skeletons.

Science.gov (United States)

Coulson-Thomas, Yvette M; Norton, Andrew L; Coulson-Thomas, Vivien J; Florencio-Silva, Rinaldo; Ali, Nadir; Elmrghni, Samir; Gil, Cristiane D; Sasso, Gisela R S; Dixon, Ronald A; Nader, Helena B

2015-06-01

Morphological and ultrastructural data from archaeological human bones are scarce, particularly data that have been correlated with information on the preservation of molecules such as DNA. Here we examine the bone structure of macroscopically well-preserved medieval human skeletons by transmission electron microscopy and immunohistochemistry, and the quantity and quality of DNA extracted from these skeletons. DNA technology has been increasingly used for analyzing physical evidence in archaeological forensics; however, the isolation of ancient DNA is difficult since it is highly degraded, extraction yields are low and the co-extraction of PCR inhibitors is a problem. We adapted and optimised a method that is frequently used for isolating DNA from modern samples, Chelex(®) 100 (Bio-Rad) extraction, for isolating DNA from archaeological human bones and teeth. The isolated DNA was analysed by real-time PCR using primers targeting the sex determining region on the Y chromosome (SRY) and STR typing using the AmpFlSTR(®) Identifiler PCR Amplification kit. Our results clearly show the preservation of bone matrix in medieval bones and the presence of intact osteocytes with well preserved encapsulated nuclei. In addition, we show how effective Chelex(®) 100 is for isolating ancient DNA from archaeological bones and teeth. This optimised method is suitable for STR typing using kits aimed specifically at degraded and difficult DNA templates since amplicons of up to 250bp were successfully amplified. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Determinación de sílice libre en materias primas para la industria del cemento

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Calleja, J.

1965-12-01

Full Text Available Not availableLa existencia de sílice libre en las materias primas y, por lo tanto, en los crudos empleados en la fabricación de cemento Portland es desventajosa por la escasa reactividad de esta sílice, sobre todo si no posee una finura suficiente. La determinación de sílice cuarzosa en tales materiales es decisiva para la buena marcha de la clinkerización en fábricas cuyas materias primas adolecen de la desventaja de contenerla. Los métodos propugnados suelen ser poco reproducibles y precisos, y dan resultados bastante erráticos. En el presente trabajo, y después de haber ensayado diversos métodos citados en la bibliografía, se describe y recomienda un procedimiento, basado en el ataque del material por ácido pirofosfórico. Las variables que juegan en el proceso descrito son el tamaño de grano de la muestra, en particular el de la sílice libre, la temperatura y el tiempo de ataque. En las condiciones que se especifican se consigue una disolución prácticamente total de los silicatos, sin que apenas se· disuelvan las partículas más finas de cuarzo. Con ello se consigue una exactitud y una precisión tal como pone de manifiesto el análisis estadístico de los resultados obtenidos al determinar sílice libre en diversas materias primas y crudos para cemento.

Das representações míticas à cultura clerical: as Fadas da Literatura Medieval

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Antonio P.V. Morás

1999-01-01

Full Text Available O presente artigo estuda a permanência dos mitos celtas no folclore medieval e como seus temas e motivos são assimilados pela cultura clerical do século XII em diante. O principal propósito do mesmo é analisar a dimensão simbólica dos mitos celtas e o deslocamento de seu sentido original nos textos produzidos no meio cavaleiresco.The present article studies the constancy of the celtic myths in the medieval folklore and how its themes and motifs are assimilated for the clerical culture of the XIIth. century and forth. The principal purpose of this article is analyse the symbolical dimension of the celtic myths and the displacement of its original sense in the literary texts produced in the chivalrous environment.

Galeata: chronic migraine independently considered in a medieval headache classification

OpenAIRE

Guerrero-Peral, Ángel Luís; de Frutos González, Virginia; Pedraza-Hueso, María Isabel

2014-01-01

Background Chronic migraine is a quite recent concept. However, there are descriptions suggestive of episodic migraine since the beginning of scientific medicine. We aim to review main headache classifications during Classical antiquity and compared them with that proposed in the 11th century by Constantine the African in his Liber Pantegni, one of the most influential texts in medieval medicine. Method We have carried out a descriptive review of Henricum Petrum's Latin edition, year 1539. Re...

Medieval codes of ius commune in Portugal: status quaestionis

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José Domingues

2016-12-01

Full Text Available Portugal inherited from the kingdom of León legal sources and its earliest law code. With the “rebirth” of Roman law, the Ius commune –arriving very early in the twelfth century– soon came to shape everyday life, from the middle ages until the Enlightenment of the late eighteenth century. Enormous research efforts have been made to locate chronologically and spatially medieval remnants of these legal texts. This work aims to provide a summary, including a comprehensive and updated picture, of the status quaestionis of this theme.

Study on the irradiation decontamination of traditional Chinese medicines

International Nuclear Information System (INIS)

Wang, B.; Shi, S.; Li, B.; Wang, G.

2005-01-01

Traditional Chinese Medicines (TCMs) are natural products prepared from plants, minerals and animals, it is easy for contamination by microorganisms to occur; thus causing problems in complying with the requirements laid down for passing microbial limit tests. We selected some kinds of TCMs, including unprocessed materia medica, traditional Chinese patent medicine (TCPMs) and chemical constituents for irradiation by 60 Co gamma ray and investigating the results in terms of microbiology, chemistry, pharmacology and toxicology. We found no evidence of changes in most of the tested items, which indicates that the irradiation method could be employed for decontamination of TCMs. However, some chemical constituents of unprocessed materia medica, such as gentiopicrin in Radix Gentianae Macrophyllae and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in Radix Polygoni Multiflori, decomposed when these crude materials were irradiated with dose of 5kGy. Further study revealed that although the medicinal were altered by irradiation, the monomers of some of these chemical constituents were not affected. In addition to investigation of the items described above, the doses of irradiation were selected experimentally to ensure that, after irradiation, the TCMs passed the microbial limit tests described in the Chinese Pharmacopoeia. The lowest possible doses were used in order to avoid any impairment of the quality and clinical efficacy of the effective ingredients of the TCMs. (author)

A medieval city within Assyrian walls: the continuity of the town of Arbil in Northern Mesopotamia

Czech Academy of Sciences Publication Activity Database

Nováček, K.; Amin, A.M.; Melčák, Miroslav

2013-01-01

Roč. 75, autumn (2013), s. 1-42 ISSN 0021-0889 Institutional support: RVO:68378009 Keywords : medieval Arbil * North Mesopotamia * topography * remote sensing * archeology Subject RIV: AC - Archeology, Anthropology, Ethnology

Opisthorchiasis in infant remains from the medieval Zeleniy Yar burial ground of XII-XIII centuries AD

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Sergey Mikhailovich Slepchenko

2015-01-01

Full Text Available We present a paleoparasitological analysis of the medieval Zeleniy Yar burial ground of the XII-XII centuries AD located in the northern part of Western Siberia. Parasite eggs, identified as eggs of Opisthorchis felineus, were found in the samples from the pelvic area of a one year old infant buried at the site. Presence of these eggs in the soil samples from the infant’s abdomen suggests that he/she was infected with opisthorchiasis and imply consumption of undercooked fish. Ethnographic records collected among the population of the northern part of Western Siberia reveal numerous cases of feeding raw fish to their children. Zeleniy Yar case of opisthorchiasis suggests that this dietary custom has persisted from at least medieval times.

On the distribution of trace element concentrations in multiple bone elements in 10 Danish medieval and post-medieval individuals.

Science.gov (United States)

Lund Rasmussen, Kaare; Skytte, Lilian; D'imporzano, Paolo; Orla Thomsen, Per; Søvsø, Morten; Lier Boldsen, Jesper

2017-01-01

The differences in trace element concentrations among 19 different bone elements procured from 10 archaeologically derived human skeletons have been investigated. The 10 individuals are dated archaeologically and some by radiocarbon dating to the medieval and post-medieval period, an interval from ca. AD 1150 to ca. AD 1810. This study is relevant for two reasons. First, most archaeometric studies analyze only one bone sample from each individual; so to what degree are the bones in the human body equal in trace element chemistry? Second, differences in turnover time of the bone elements makes the cortical tissues record the trace element concentrations in equilibrium with the blood stream over a longer time earlier in life than the trabecular. Therefore, any differences in trace element concentrations between the bone elements can yield what can be termed a chemical life history of the individual, revealing changes in diet, provenance, or medication throughout life. Thorough decontamination and strict exclusion of non-viable data has secured a dataset of high quality. The measurements were carried out using Inductively Coupled Plasma Mass Spectrometry (for Fe, Mn, Al, Ca, Mg, Na, Ba, Sr, Zn, Pb and As) and Cold Vapor Atomic Absorption Spectroscopy (for Hg) on ca. 20 mg samples. Twelve major and trace elements have been measured on 19 bone elements from 10 different individuals interred at five cemeteries widely distributed in medieval and renaissance Denmark. The ranges of the concentrations of elements were: Na (2240-5660 µg g -1 ), Mg (440-2490 µg g -1 ), Al (9-2030 µg g -1 ), Ca (22-36 wt. %), Mn (5-11450 µg g -1 ), Fe (32-41850 µg g -1 ), Zn (69-2610 µg g -1 ), As (0.4-120 µg g -1 ), Sr (101-815 µg g -1 ), Ba (8-880 µg g -1 ), Hg (7-78730 ng g -1 ), and Pb (0.8-426 µg g -1 ). It is found that excess As is mainly of diagenetic origin. The results support that Ba and Sr concentrations are effective provenance or dietary indicators. Migrating

CARACTERIZACIÓN ESTRUCTURAL DE LA MATERIA ORGÁNICA DE TRES SUELOS PROVENIENTES DEL MUNICIPIO DE AQUITANIA BOYACÁ, COLOMBIA

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Carmen S. Mosquera

2010-09-01

Full Text Available La materia orgánica del suelo puede variar considerablemente en su estructura, composición y conformación, de acuerdo con el origen y la edad de los materiales que la constituyen. En la presente investigación se procedió a caracterizar, mediante el empleo de la espectroscopia infrarroja y la resonancia magnética nuclear en estado sólido, dos suelos inceptisoles (I01 y I02 y un histosol (H03 destinados al cultivo de cebolla larga, en el municipio de Aquitania-Boyacá, Colombia, a dos profundidades: 0 - 10 y 40 - 50 cm. Según los espectros infrarrojos, se detectó la presencia de grupos OH (debida posiblemente a fenoles, ácidos carboxílicos o alcoholes, grupos aromáticos y alifáticos. Los espectros de 13C-RMN en estado sólido con CPMAS evidenciaron el siguiente orden respecto a la cantidad de carbonos que conforman la materia orgánica del suelo: H03-0 = 100 y H03 -40 = 88, I02-0 = 23 y I02-40 = 0, y finalmente I01-0 = 17 y I01-40 = 12, confirmándose la disminución de carbonos en la materia orgánica a través del perfil del suelo, y además se estableció que el carbón resonante en la región delta = 108-50 ppm de los espectros (N – y O-alquilos y acetales dominó en toda la MOS obtenida; le siguió el carbón aromático (delta = 168-108 ppm para los suelos I01-0 y H03-40, y el carbón alifático (delta = 0-50 ppm para los suelos I01-40, I02-0 y H03-0. Finalmente, el carbónC=O( delta= 220-162 ppm fue el menos dominante en la materia orgánica del suelo en todos los tres suelos caracterizados.

The archaeology of early medieval violence: the mass grave at Budeč, Czech Republic

Czech Academy of Sciences Publication Activity Database

Štefan, I.; Stránská, Petra; Vondrová, H.

2016-01-01

Roč. 90, č. 351 (2016), s. 759-776 ISSN 0003-598X Institutional support: RVO:67985912 Keywords : Czech Republic * Bohemia * Budeč * tenth-eleventh centuries * early medieval * mass grave * violence * warfare Subject RIV: AC - Archeology, Anthropology, Ethnology Impact factor: 1.536, year: 2016

Characterisation of early medieval frescoes by μ-PIXE, SEM and Raman spectroscopy

International Nuclear Information System (INIS)

Zucchiatti, A.; Prati, P.; Bouquillon, A.; Giuntini, L.; Massi, M.; Migliori, A.; Cagnana, A.; Roascio, S.

2004-01-01

We have studied the VIII-IX century frescoes of the Longobard temple of Cividale del Friuli in Italy with noninvasive sampling and, for the first time in such a context, with high chemical and spatial sensitivity techniques (PIXE, SEM and Raman). Results demonstrate richness of manufacturing details and integrate in a substantial way the historic and artistic framework of this early medieval monument

Characterisation of early medieval frescoes by {mu}-PIXE, SEM and Raman spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Zucchiatti, A. E-mail: zucc@ge.infn.it; Prati, P.; Bouquillon, A.; Giuntini, L.; Massi, M.; Migliori, A.; Cagnana, A.; Roascio, S

2004-06-01

We have studied the VIII-IX century frescoes of the Longobard temple of Cividale del Friuli in Italy with noninvasive sampling and, for the first time in such a context, with high chemical and spatial sensitivity techniques (PIXE, SEM and Raman). Results demonstrate richness of manufacturing details and integrate in a substantial way the historic and artistic framework of this early medieval monument.

The Bistrup Project: a comparison of floor-tiles from Medieval churches by means of neutron activation analysis

International Nuclear Information System (INIS)

Als Hansen, B.; Aaman Soerensen, M.; Heydorn, K.; Hoejslet Christensen, L.; Mejdahl, V.; Winther-Nielsen, M.; Conradsen, K.

1982-01-01

Medieval, decorated floor-tiles from a number of churches in and around Roskilde, Denmark, have been compared with identically ornamented wasters of floor-tiles found inside two kilns excavated at Bistrup near Roskilde and with clay from Bistrup and Oroe. For each sample the concentrations of 14 elements were determined by means of neutron activation analysis, and the results were submitted to a stepwise discriminant analysis. All floor-tile groups showed a distinct similarity to the groups of wasters and clay from Bistrup, and the result is thus compatible with the archaeological view that during the Medieval period Bistrup functioned as a production centre for tiles impregnated with these particular ornamentations. (author)

[Tooth macromorphological and ultrastructural analysis of osteological material from the medieval locality of St. Panteleimon Church in Nis].

Science.gov (United States)

Mitić, Nadica; Mitić, Aleksandar; Mitić, Vladimir; Savić, Vojin; Nikolić, Marija

2010-01-01

Analysis of macromorphological and ultrastructural tooth characteristics of osteological material from the medieval site of St. Pantaleimon Church in Nis provides us with insight on the life, nutrition and habits of medieval population, as well as the structure and composition of their teeth. The aim of this research, based on the tooth inspection of skeletal remains from the medieval site of St. Pantaleimon Church in Nis, was to analyze macromorphological characteristics, ultrastructure of the dental tissue of maxillary and mandibular molars, canines and incisors, as well as their chemical composition. Macromorphological and ultrastructural analysis of the dental tissue of osteological material dating from the 12th century included 1312 teeth with advanced abrasion. Macromorphological changes were detected by using a dental mirror, probe and radiography. After irrigation, the teeth were prepared using the standard procedure and analyzed by scanning electronic microscopy (JEOL-JSM-5300). Chemical analysis was done by expanded downscaling (EDS) method for Mg, P, Ca. The analysis detected second degree abrasions of all teeth in individuals aged 20-25 years. Third and fourth degree abrasions of teeth were detected in individuals aged over 40 years. Ultrastructural analysis showed a complete obliteration of dentin tubules and pulp of the lower incisors, the apposition of intratubular dentin inside the tubules, as well as extensive deformity and loss of dentin structure on molars with preserved pulp volume and nerve fiber calcification. The calcification of nerve fibers showed that the formation of intratubular dentin was proportional with the biological potential of pulp and the degree of abrasion, and inversely proportional with the size of dentin surface. Chemical analysis showed that in the analyzed teeth Ca composition was slightly lower than that in the control group, P composition was almost identical, while Mg composition was multiply increased in comparison to

"Quid dant artes nisi luctum?": Learning, Ambition, and Careers in the Medieval University.

Science.gov (United States)

Ferruolo, Stephen C.

1988-01-01

Focusing on the medieval university during its formative years (late 1100s and early 1200s), the author addresses questions such as "How did the ambitions of students and masters influence the organization and curriculum of these new institutions?" Concludes that society was served by these universities despite the indication that the…

The Advances in Research on the Pharmacological Effects of Fructus Ligustri Lucidi

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Zunting Pang

2015-01-01

Full Text Available Fructus Ligustri Lucidi is a well-known invigorator in Chinese materia medica with hepatoprotective effect, anticancer activity, antioxidant activity, and so on. And oleanolic acids are the major pharmacologically active components in Fructus Ligustri Lucidi. So it has great value in medical health, and may be developed to a complementary and alternative medicine through further research. In this paper, the advances in research on pharmacological effects of Fructus Ligustri Lucidi were summarized by reviewing the recent related literature.

d-?-Tocopheryl polyethylene glycol succinate/Solutol HS 15 mixed micelles for the delivery of baohuoside I against non-small-cell lung cancer: optimization and in vitro, in vivo evaluation

OpenAIRE

Yan, Hongmei; Zhang, Zhenhai; Jia, Xiaobin; Song, Jie

2016-01-01

Hongmei Yan,1,2 Zhenhai Zhang,2 Xiaobin Jia,1,2 Jie Song1,2 1College of Pharmacy, Nanjing University of Chinese Medicine, 2Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Third School of Clinical Medical of Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China Abstract: Baohuoside I, extracted from the Herba epimedii, is an effective but a poorly soluble antitumor drug. To improve its solubility, formulation of baohuoside I-load...

Man, nutrition and mobility: A comparison of teeth and bone from the Medieval era and the present from Pb and Sr isotopes

International Nuclear Information System (INIS)

Aberg, G.; Stray, H.; Fosse, G.

1998-01-01

Naturally occurring isotopic systems, such as strontium (Sr) and lead (Pb), are very useful for characterizing different sources and to produce background information. Norwegian teeth from the Medieval era have 206 Pb/ 204 Pb ratios between 18.8 and 18.2, in comparison with present day ratios of between 18.0 and 17.6 showing the impact of Pb from modern industrialization and from traffic. Sr analyses of Medieval teeth show that an individual living in a coastal town on the west coast of Norway can easily be distinguished from one in a rural area at that time. The Sr signature shows that Medieval people lived on local products while present people to a greater degree live on imported or domestic industrially processed food. Medieval and modern teeth from one site give similar Pb signatures and concentrations indicating no increase in pollution over time. However, the impact of industrial pollution can be seen from Pb analyses on contemporary teeth, so that the method can be used to monitor emission of heavy metals from local industry. Whilst the Pb and Sr natural isotopic systems individually provide valuable information, a combination of the two techniques is a very powerful tool in environmental and archaeological research. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

Clinical and radiographical evaluation of mineral trioxide aggregate, biodentine and propolis as pulpotomy medicaments in primary teeth

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Bharti Kusum

2015-11-01

Full Text Available Objectives The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA, Biodentine and Propolis as pulpotomy medicaments in primary dentition, both clinically and radiographically. Materials and Methods A total of 75 healthy 3 to 10 yr old children each having at least one carious primary molar tooth were selected. Random assignment of the pulpotomy medicaments was done as follows: Group I, MTA; Group II, Biodentine; Group III, Propolis. All the pulpotomized teeth were evaluated at 3, 6, and 9 mon clinically and radiographically, based on the scoring criteria system. Results The clinical success rates were found to be similar among the three groups at 3 and 6 mon where as a significant decrease in success rate was observed in Group III (84% compared to both Group I (100% and Group II (100% at 9 mon. Radiographic success rates over a period of 9 mon in Groups I, II, and III were 92, 80, and 72%, respectively. Conclusions Teeth treated with MTA and Biodentine showed more favorable clinical and radiographic success as compared to Propolis at 9 mon follow-up.

Study on the Property Change of Rhizoma Coptidis and Its Ginger Juice Processed Products Based on 5-Ht Level and Brain Tissues Morphology of Rats

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Zhong, Lingyun; Tong, Hengli; Lv, Mu; Deng, Yufen

2017-09-01

According to the theory of traditional Chinese Medicine (TCM), all Chinese materia medica need to be processed using Pao zhi which is a processing technology before being used in clinic. Ginger juice, made from dried or fresh ginger, is one of the main TCM processing accessories and always used to help change some Chinese materia medica’s properties for its warm or hot nature. The purpose of this paper is to discuss the influence of ginger juice on Rhizoma Coptidis (RC) by determining 5-hydroxytryptamine (5-HT) content and observing morphological changes in the harns tissue of rats. Raw Rhizoma Coptidis (RRC), fresh ginger juice processed Rhizoma Coptidis (FGJPRC), dried juice processed Rhizoma Coptidis (DGJPRC), dried ginger juice (DGJ) and fresh ginger juice (FGJ) were prepared using appropriate methods. Immunohistochemical staining was used to observe the distribution of 5-HT and fluorescence spectrophotometry was applied to determine 5-hydroxytryptamine content in the brain tissue of rats. 5 - HT in brain tissue of the rats of RRC group was distributed most densely, with the highest content. Compared to the blank group, RRC and different ginger processed RC groups could lead to increasing content of 5-HT in rat encephalon, and significant differences in RRC. Compared with the RRC, the 5-HT content in rat encephalon in DGJPRC, FGJPRC, FGJ and DGJ groups reduced, and DGJPRC, FGJPRC groups showed significant difference, FGJ and DGJ groups showed extreme significant differences. The research showed that processing with hot, warm accessories would moderate the cold nature of RC. The cold and hot nature of Traditional Chinese Materia Medica could be expressed by the difference of 5-HT contents and morphological changes of rats’ brain tissue. Simultaneously, the research showed the different excipient of ginger juice would have different effects on the processing of RC.

A spectroscopic study of Brazilwood paints in medieval books of hours.

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Melo, Maria João; Otero, Vanessa; Vitorino, Tatiana; Araújo, Rita; Muralha, Vânia S F; Lemos, Ana; Picollo, Marcello

2014-01-01

In this work, microspectrofluorimetry was for the first time applied to the identification of the red organic lakes that are characteristic of the lavish illuminations found in 15(th) century books of hours. Microspectrofluorimetry identified those red paints, ranging from opaque pink to dark red glazes, as brazilwood lakes. An unequivocal characterization was achieved by comparison with reference paints produced following recipes from the medieval treatise The Book on How to Make Colours, and was further confirmed by fiber optic reflectance spectroscopy (FORS). For these treasured cultural objects, microspectrofluorimetry and FORS proved to be the only techniques that could identify, in situ or in microsamples, the chromophore responsible for the pinkish hues: a brazilein-Al(3+) complex. Additionally, a multi-analytical approach provided a full characterization of the color paints, including pigments, additives, and binders. Microspectroscopic techniques, based on infrared and X-ray radiation, enabled us to disclose the full palette of these medieval manuscripts, including the elusive greens, for which, besides malachite, basic copper sulfates were found; Raman microscopy suggested a mixture of brochantite and langite. Infrared analysis proved invaluable for a full characterization of the additives that were applied as fillers or whites (chalk, gypsum, and white lead) as well as the proteinaceous and polysaccharide binders that were found pure or in mixture.

[Medieval scenes of ritual circumcision as a reflection of sociopolitical circumstances].

Science.gov (United States)

Pust, R A; Drost, C; Willerding, H; Bschleipfer, T

2005-03-01

Ritual circumcision in males is regarded as one of the oldest surgical procedures. Whereas their medieval illustrations are mostly interpreted within a religious context, this study tries to prove the influence of the political and social situation of the above-mentioned period.Selected iconography of ritual male circumcision in the Middle Ages from Germany, France, Italy, and the Byzantine Empire was critically examined. Special attention was paid to the stained glass windows recently returned to St. Mary's Church in Frankfurt/Oder, where circumcision of the so-called Antichrist is also shown. Up to now we could not find any medical historical information about this subject. Clerical fine art of the fifteenth and sixteenth centuries shows more frequently than before illustrations of ritual circumcision, which evidently demonstrate the political, economic, and social tensions and controversies of that period. In many cases this iconography indicates a rejection of this old Jewish tradition and its confessors. Also the stained glass image of the Antichrist posthetomy could be interpreted as criticism or aversion.This study expands our approach to medieval illustrations of ritual circumcision that have hitherto mostly been interpreted in religious terms. The influence of changing political and social situations in the Middle Ages is evident.

Manual para la negociación colectiva inclusiva en materia de discapacidad

OpenAIRE

CERMI

2013-01-01

El Comité Español de Representantes de Personas con Discapacidad (CERMI) ha elaborado el ‘Manual de negociación colectiva inclusiva en materia de discapacidad’ que pretende proporcionar a los agentes sociales una herramienta para incluir la discapacidad en todos los ámbitos de la empresa que dependen del concierto social. La guía pretende ayudar a extender la cultura de la inclusión de la discapacidad en los convenios colectivos que negocian los agentes sociales como por ejemplo: condicion...

NCG56/31: Reglamento de R??gimen Interno del Departamento de Electromagnetismo y F??sica de la Materia

OpenAIRE

Universidad de Granada

2012-01-01

Reglamento de R??gimen Interno del Departamento de Electromagnetismo y F??sica de la Materia. Aprobado en sesi??n extraordinaria del Consejo de Gobierno de la Universidad de Granada celebrada el 20 de febrero de 2012.

El comercio de los esclavos musulmanes en el Portugal medieval : rutas y papel económico

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François Soyer

2010-01-01

Full Text Available Actualmente existen muy pocos estudios acerca de la esclavitud musulmana en Portugal. Cuando se trata el comercio de los esclavos en la historia portuguesa, generalmente los trabajos se refieren al comercio de los esclavos africanos que los navegantes portugueses comenzaron traer de vuelta a Europa desde el año 1441 en adelante, a pesar de que desde el siglo XI existía una pobulación de esclavos musulmanes —los llamados mouros cativos—. En este artículo propongo estudiar, de la forma la más detallada posible, las características y dinámicas del comercio de los esclavos musulmanes en el reino cristiano de Portugal durante la Edad Media, tratando de responder a preguntas relevantes, como las de cuál era el origen y el papel económico de los esclavos musulmanes en el Portugal medieval, qué sabemos del comercio de los esclavos en aquel reino, o a la cuestión de si Portugal fue un país exportador o importador de esclavos.Whilst the presence of Muslim slaves in medieval Spain has attracted considerable scholarly attention from historians both inside and outside of the Iberian Peninsula, the same cannot be said of the history of Muslim slaves in the medieval Christian kingdom of Portugal. Most studies of slavery in Portugal focus on captives from sub-Saharan Africa brought back by Portuguese slavers to Europe from 1441 onwards even though Muslim slaves were present in Portugal from the eleventh century at the very least. We know next-to-nothing about these Muslim slaves. This article proposes to examine in as much detail as possible the characteristics and dynamics of the commerce of Muslim slaves in medieval Portugal. It addresses problematic questions regarding the origins and economic role of Muslim slaves in premodern Portugal, the nature of slave trading and whether Portugal was an importer or exporter of slaves.

The basis of the modern medical hygiene in the medieval Medical School of Salerno.

Science.gov (United States)

Bifulco, Maurizio; Capunzo, Mario; Marasco, Magda; Pisanti, Simona

2015-01-01

The link between hygiene and the concept of transmission of infective diseases was established earlier than the birth of microbiology, thanks to the studies of two neglected physicians of maternity clinic, Ignác Fülöp Semmelweis and Oliver Holmes, in the mid-1800s. Surprisingly, centuries earlier, a medieval women physician, Trotula de Ruggiero, introduced for the first time the notion of diseases’ prevention, highlighting the importance of the association of personal hygiene, balanced nutrition and physical activity for better health. Moreover, she was particularly concerned of hands hygiene for the midwives during child birth, to preserve the good health of both the mother and the baby. She practiced inside the medieval Medical School of Salerno, whose main text, the “Regimen Sanitatis Salerni” has an entire part dedicated to hygiene, providing hygienic precepts that anticipate the concepts derived from the revolutionary discoveries in medical science only centuries later.

Classification of medieval ceramics in the Rhineland and neighbouring areas by neutron activation analysis

International Nuclear Information System (INIS)

Mommsen, H.; Hein, A.

1997-01-01

Instrumental neutron activation analysis (INAA) is known to be well suited for provenance determinations of ceramics, since more than 25 minor and trace elements can be measured with precisions high enough to discriminate between different pottery production workshops. INAA-data are presented for more than 1500 shards, mostly wasters, produced in different places such as Brueggen/Elmpt, Brunssum/Schinveld, Frechen/Cologne, Hoehr-Grenzhausen, Mayen, Paffrath, Pingsdorf/Bruehl, Raeren and Siegburg, to name only the most important earthen and stoneware production centres of the Rhine area in medieval and post medieval times. It turned out, that the wares of these different centres, although by archeological criteria often very similar, can be clearly recognized by INAA. This large reference databank can now be used to determine export pieces from these centres and to trace trade relations in the Middle Ages. An examples of a provenance determination of questionable finds of Pingsdorf and Paffrath Ware from Emden is given. (author)

Funcionamento intelectual em pacientes pediátricos com epilepsia: comparação de crianças controladas com medicação, não controladas com medicação e controladas com cirurgia Intellectual functioning in pediatric patients with epilepsy: a comparison of medically controlled, medically uncontrolled and surgically controlled children

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Cecília Souza-Oliveira

2010-10-01

Full Text Available OBJETIVO: Comparar o quociente intelectual (QI em três grupos de crianças com epilepsia: 1 controlados com medicação, 2 não controlados com medicação e 3 controlados com cirurgia. MÉTODOS: Noventa e oito pacientes pediátricos, com idades entre 6 e 12 anos, foram selecionados de dezembro de 2007 a julho de 2008. A Escala de Inteligência Wechsler para Crianças - terceira edição (WISC-III foi utilizada para a avaliação neuropsicológica dos pacientes. Os resultados foram relacionados com a síndrome epiléptica, a etiologia da epilepsia, o tratamento medicamentoso, a idade do paciente no início da epilepsia e a duração da epilepsia. RESULTADOS: Os escores da WISC foram significativamente melhores no grupo controlado com medicação quando comparados aos do grupo não controlado com medicação. O grupo controlado com medicação obteve um desempenho significativamente melhor na maioria dos subtestes da WISC quando comparado ao grupo não controlado com medicação: vocabulário, aritmética, compreensão, memória de dígitos, completar figuras, arranjo de figuras e cubos. Um número significativamente maior de pacientes com epilepsia idiopática e uso de monoterapia foi observado no grupo controlado com medicação quando comparado ao grupo não controlado. O grupo controlado com cirurgia não apresentou diferença significativa no desempenho do QI quando comparado ao grupo controlado com medicação. CONCLUSÕES: As crianças com um bom controle de crises tiveram um melhor desempenho no QI geral, verbal e de execução quando comparadas às crianças com epilepsia refratária. Esses resultados podem ser influenciados por fatores clínicos como o uso de monoterapia, o tipo de droga antiepiléptica utilizada, a síndrome epiléptica e a etiologia da epilepsia. A cirurgia de epilepsia pode causar um impacto positivo no desempenho cognitivo das crianças que ficaram livres de crises após o procedimento cirúrgico.OBJECTIVE: To

Determination of the origin of the medieval glass bracelets discovered in Dubna, Moscow Region, Russia, using the neutron activation analysis

International Nuclear Information System (INIS)

Dmitrieva, S.O.; Frontasyeva, M.V.; Dmitriev, A.Yu.; Dmitriev, A.A.

2017-01-01

The work is dedicated to the determination of the origin of archaeological finds from medieval glass using the method of neutron activation analysis (NAA). Among such objects we can discover things not only produced in ancient Russian glassmaking workshops but also imported from Byzantium. The authors substantiate the ancient Russian origin of the medieval glass bracelets of pre-Mongol period, found on the ancient Dubna settlement. The conclusions are based on data on the glass chemical composition obtained as a result of NAA of 10 fragments of bracelets at the IBR-2 reactor, FLNP, JINR.

Una mención medieval de los ispallenses de Plinto (Nh.III, 24

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Carlos Javier CABALLERO CASADO

2010-02-01

Full Text Available RESUMEN: En este artículo se plantea la identidad de los ispallenses citados por Plinto (NH, III, 24 en la lista de pueblos pertenecientes al Convento Jurídico Cesaraugustano con el topónimo Spalanam, señalado como límite común de las diócesis de Osea y Caesaraugusta en la División de Wamba, documento medieval de principios del siglo XII.A partir de la relación entre ambos topónimos y el texto del triffinium de Fuentes de Ebro (Zaragoza, se realiza un ensayo de localization de los ispallenses plinianos.ABSTRACT: In this paper we propose the identity between the ispallenses mentioned by Pliny's Natural History (III, 24 and the place-name Spallanam, mentioned as common boundery between the bishoprics of Osea and Caesaraugusta in the book División de Wamba, a medieval document probably written at the beginning of 12th. Century From the relationship between this two place-names and the text conserved in Fuentes de Ebro's (Zaragoza triffinium, we try to situate those plinian's ispallenses.

Exposition des ymages des figures qui sunt: discourses about images in Medieval Occident

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Maria Cristina Correia Leandro Pereira

2016-09-01

Full Text Available Contrary to what indicates the famous – and questionable – formula "Bible des illetrés”, the medieval discourses on images went well beyond just highlighting its didactic function. In this article, we present a sample of this diversity, analyzing a number of medieval texts dealing with images, which we have divided into five broad categories (not mutually exclusive: on the contrary, sometimes complementary. The first and most numerous are the theoretical discourses on images involving theological questions. Then, still based on arguments of theological order, a second group corresponds to those texts that seek to intervene in the practice of images through normative propositions. As a result from the previous two types is the third group: the speeches dealing with the reception of images and the reactions they cause. A fourth group are the writings that mention the producers of images: both practical documents and those that express value judgments about their Works. And finally, there are texts that describe the images, both their iconographic content and their materiality.

Combined GPR and ERT exploratory geophysical survey of the Medieval Village of Pancorbo Castle (Burgos, Spain)

Science.gov (United States)

Fernández-Álvarez, José-Paulino; Rubio-Melendi, David; Quirós Castillo, Juan Antonio; González-Quirós, Andrés; Cimadevilla-Fuente, David

2017-09-01

Ground-penetrating Radar (GPR) and Electrical Resistivity Tomography (ERT) have been fruitfully employed for archaeological purposes. An area at the Pancorbo medieval site in Burgos (Spain) has been jointly explored by GPR and ERT in the search for the buried remains of the Pancorbo medieval village. After data collection, quality control and merging, a shallow depth of interest was identified and studied in detail. 3D resistivity simulation, considering sensible geometrical structures of the targets helped discover anomalies present in the area. On the other hand, visual GPR inspection was considerably enhanced by trace energy attribute analysis which provided a plan view of the existing anomalies. Two posterior archaeological excavations have a very good correlation between the identified anomalies and the excavated remains. The survey also provides hints for the continuation of the excavation.

Location-based technology and game-based learning in secondary education: learning about medieval Amsterdam

NARCIS (Netherlands)

Admiraal, W.; Akkerman, S.; Huizenga, J.; van Zeijts, H.

2009-01-01

Mobile games in education are excellent ways to combine situated, active and constructive learning with fun. In the mobile city game Frequency 1550 teams -of four students each- step into the game's world. With help of the Internet, smart phones and GPS technology, Amsterdam changes into a medieval

ACTIVE BRIBERY IN CROATIAN MEDIEVAL AND MODERN LAW

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Mijo Galiot

2016-01-01

Full Text Available When it comes to writing about the history of punishment, it is always linked with critically re-thinking and better understanding of the contemporary system of punishment, as a result of its long historical development. In such a way, „contemporary criminal law cannot be seen as a result of an effort made by a certain nation or in a certain epoch“. „Permanently faced with social changes, in its long historical development, criminal law has been modifying its fundamental principles and categories, by building new institutes and instruments, in order to become less cruel and more human, but not less efficient than in earlier stages of its development, characterized by rudeness, cruelty and exemplarity of its sanctions. Although it is not easy to answer the question, if there is the measure, in which social understanding of punishment and its purpose, determines the civilizational level in the society, there is no doubt about the fact that civilizational and legal point of view towards punishment derives from a waste range of factors: general, cultural, sociological, psychological, religious, political and other factors that should be taken altogether in their historical dimension. The genesis of criminal law is linked with the moment of establishing the public authorities and the state. According to different criteria, it is possible to introduce different periodization of criminal law. When it comes to the historical criterion, there can be made a historical division into periods of ancient, medieval, modern and contemporary criminal law (punishment, which periods should not be taken as absolutely inseparable. The point of this paper is to present a review and development of punishing active bribery in the Croatian medieval and modern law.

ECOHYDROLOGICAL PERSPECTIVES OF DEGRADING BAOLIS DURING MEDIEVAL PERIOD IN DELHI: traditional practices of water management

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Subhash Anand

2017-03-01

Baolis es el depósito de agua en los monumentos arquitectónicos que habían sido construidos por varios sultanato de Delhi en diferentes períodos de tiempo y la mayoría de Baolis fueron construidos durante el período de tiempo medieval. Los Baolis se encuentran en todo el país, pero todos son diferentes en lo que respecta al arte y la arquitectura. Los sultanatos de Delhi habían construido una serie de Baolis en Delhi para mostrar su control y prestigio en la sociedad. Hay alrededor de 12 Baolis existentes en Delhi y de ellos, cuatro Baolis están a punto de extinguirse y pocos Baolis como Nizamuddin, Firoz Shah y Rajon ki Baolis están siendo utilizados por la gente local. Este artículo comprende la información relacionada con Baolis que fue construida por sultanatos de Delhi durante el período de tiempo medieval en Delhi. El presente trabajo intenta describir el método tradicional de gestión del agua como Baolis en época medieval y su estado actual. El estudio se basa en fuentes primarias y secundarias de información y se realizó una encuesta primaria y personal y se han utilizado fuentes secundarias de datos e información en este documento. El artículo concluyó que Baolis no está teniendo buenas condiciones y estas están muy contaminadas y degradadas y su degradación también conduce a la pérdida ecológica hidrológica en sus áreas adyacentes. Los acercamientos descuidados de la gente hacia estos Baolis son causas principales detrás de la extinción y de la degradación de estos Baolis. La conciencia de la comunidad y la participación es la única manera de proteger a estos Baolis de la extinción. Palabras clave: Baolis; Arquitectónico; Monumento; Medieval; Degradación; Eco hidrología; Contaminación; Manejo.

Adaptación de dos piezas distintas a una pieza bi-materia

OpenAIRE

Gómez Acevedo, Rocío

2014-01-01

El presente proyecto se ha realizado en la empresa Faurecia Automotive Exteriors [Anexo-A], para la pieza llamada Spoiler del proyecto parachoques delantero A05GPPOLO del grupo Volkswagen (VW). Dicho proyecto se enfoca en la adaptación de dos piezas compuestas por polímeros diferentes en una única pieza bi-materia, utilizando la técnica de inyección multi-componente. Se ha partido de un estudio teórico previo sobre la posible compatibilidad entre la unión rígido-suave de los mater...

Cooperación internacional en materia penal en el MERCOSUR: el cibercrimen

OpenAIRE

Santiago Deluca; Enrique Del Carril

2017-01-01

En el Mercosur no existe un derecho penal común, no obstante observarse una creciente corriente orientada a la adopción de normas generales de política criminal tendiente a combatir diversos actos delictivos. Ello se cristaliza en la creación de normas de cooperación internacional en materia penal, con el objeto de lograr la asimilación y adecuación “macro” de las legislaciones penales de los Estados Parte. Es justo reconocer que en este trabajo no se pretende elaborar un corpus iuris por ...

Producción de biodiesel a partir de materias primas no convencionales

OpenAIRE

Aguilar Sánchez, Rocío

2011-01-01

Proyecto Fin de Carrera leído en la Universidad Rey Juan Carlos en el curso académico 2010/2011. Directores del Proyecto: Gabriel Morales Sánchez y Rebeca Sánchez Vázquez Actualmente, para la producción industrial de biodiesel se emplean aceites vegetales de alta calidad como materia prima, y se utilizan catalizadores básicos homogéneos, KOH o NaOH. Los productos de reacción son FAME y glicerina. Sin embargo, debido a los problemas derivados del uso de aceites vegetales comestible...

Universality of revealed Law and reflections on religions in Medieval Islamic philosophy: a few considerations

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Sara Barchiesi

2015-05-01

Full Text Available By analysing some Medieval Islamic philosophical theories, this paper aims at investigating the approach adopted by authors such as Avicenna and Averroës in respect of religions different from those of origin (Judaism, Christianism, Zoroastrianism and Sabeism. Moreover, it reflects on the universality of Islamic religion. The author will examine these philosophers' thoughts on prophetic teaching, recalling the Platonic sources from which they were developed, she will motivate the relevance of such thoughts in political science and she will explain their purposes. Furthermore, through a comparison with several scholars who have focused on whether Islamic Law has a conventional or natural status, she will try to investigate the origins of this problem, by examining the universal message that those Islamic Medieval philosophers found in revealed Law and the reasons that led them to present it as addressed to the whole mankind.

The Cross-Cultural Kingship in Early Medieval Kāmarūpa: Blood, Desire and Magic

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Paolo Eugenio Rosati

2017-09-01

Full Text Available Kingship in early medieval Kāmarūpa (Assam was influenced by the collision of orthodox and heterodox Brahmanic traditions with various tribal cultures. Since the last part of the Śālastambha period (seventh–tenth century the royal tutelary deity of Kāmarūpa was the menstruating Kāmākhyā, an ancient kirāta goddess. According to the Puranic tradition, the cult of Kāmākhyā was absorbed within Hindu religious folds by the mytho-historical king Naraka of Kāmarūpa. According to textual and epigraphic records, Naraka was conceived by Pṛthvī (Earth goddess during her menstrual period, through a sexual intercourse with varāha (boar form of Viṣṇu. All early medieval dynasties of Kāmarūpa traced back their origins to Naraka, connecting their lines to the divine power but also to the menstrual blood—a substance considered extremely impure though powerful in Vedic and post-Vedic traditions. The king operated as a cross-cultural mediator: he was the only actor who was able to harness the produced polluted forces, through the Tantric rituals, in order to strengthen the political power. Thence, this essay aims to demonstrate, through inter- and intra-textual evidences, epigraphic records, and ethnographic data, that in Assam throughout the early medieval ages, the kingship grounded its roots in an osmotic cross-cultural process which was influenced by tribal traditions and orthodox and heterodox Hindu sects.

PIXE and PGAA - Complementary methods for studies on ancient glass artefacts (from Byzantine, late medieval to modern Murano glass)

Science.gov (United States)

Constantinescu, Bogdan; Cristea-Stan, Daniela; Szőkefalvi-Nagy, Zoltán; Kovács, Imre; Harsányi, Ildikó; Kasztovszky, Zsolt

2018-02-01

Combined external milli-beam Particle Induced X-ray Emission (PIXE) and Prompt Gamma Activation Analysis (PGAA) analysis was applied to characterize the composition of paste and colorants from some fragments of Byzantine bracelets (10th-12th Centuries AD), late medieval (17th-18th Centuries AD) and modern Murano glass pieces. As fluxes, PGAA revealed the samples are soda-lime glass, except four samples - two medieval vessel white shards and two dark Byzantine fragments of bracelets - which have potash flux. Aluminium was detected in various proportions in all samples indicating different sources for the added sand. The presence of Magnesium is relevant only in one bracelet fragment suggesting the use of plant (wood?) ash and confirming that the Byzantine bracelet is manufactured from the mixture of both types of glass (natron and plant ash based). PGAA also indicated the presence of low quantities of Cadmium, high level of Arsenic and Lead (possibly lead arsenate) in one medieval sample and of ZnO in Murano glass, and of CoO traces (maximum 0.1%) in all blue-colored Byzantine, late medieval to modern Murano glass artefacts. PIXE confirmed the use of small quantities of CoO for blue color, indicated Manganese combined with Iron for dark glass, Copper for green, Lead, Tin and an Arsenic compound (orpiment?) for yellow and in the case of modern Murano glass Selenium and Cadmium to obtain a reddish color. Despite PIXE - PIGE combination is probably the best one for glass analysis, our external milli-PIXE - PGAA methods proved to be adequate complementary tools to determine many chemical elements from glass composition - Si, Na, K, Ca, Al, Mg, various metallic oxides.

Man, nutrition and mobility: A comparison of teeth and bone from the Medieval era and the present from Pb and Sr isotopes

Energy Technology Data Exchange (ETDEWEB)

Aberg, G.; Stray, H. [Institute for Energy Technology, Box 40, N-2007 Kjeller (Norway); Fosse, G. [Department of Anatomy and Cell Biology, University of Bergen, N-5009 Bergen (Norway)

1998-12-11

Naturally occurring isotopic systems, such as strontium (Sr) and lead (Pb), are very useful for characterizing different sources and to produce background information. Norwegian teeth from the Medieval era have {sup 206}Pb/{sup 204}Pb ratios between 18.8 and 18.2, in comparison with present day ratios of between 18.0 and 17.6 showing the impact of Pb from modern industrialization and from traffic. Sr analyses of Medieval teeth show that an individual living in a coastal town on the west coast of Norway can easily be distinguished from one in a rural area at that time. The Sr signature shows that Medieval people lived on local products while present people to a greater degree live on imported or domestic industrially processed food. Medieval and modern teeth from one site give similar Pb signatures and concentrations indicating no increase in pollution over time. However, the impact of industrial pollution can be seen from Pb analyses on contemporary teeth, so that the method can be used to monitor emission of heavy metals from local industry. Whilst the Pb and Sr natural isotopic systems individually provide valuable information, a combination of the two techniques is a very powerful tool in environmental and archaeological research. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

Stable isotope evidence for sex- and status-based variations in diet and life history at medieval Trino Vercellese, Italy.

Science.gov (United States)

Reitsema, Laurie J; Vercellotti, Giuseppe

2012-08-01

The medieval period in Europe was a time of unprecedented social complexity that affected human diet. The diets of certain subgroups-for example, children, women, and the poor-are chronically underrepresented in historical sources from the medieval period. To better understand diet and the distribution of foods during the medieval period, we investigated stable carbon and nitrogen isotope ratios of 30 individuals from Trino Vercellese, Northern Italy (8th-13th c.). Specifically, we examined diet differences between subgroups (males and females, and high- and low-status individuals), and diet change throughout the life course among these groups by comparing dentine and bone collagen. Our results show a diet based on terrestrial resources with input from C(4) plants, which could include proso and/or foxtail millet. Diets of low-status males differ from those of females (both status groups) and of high-status males. These differences develop in adulthood. Childhood diets are similar among the subgroups, but sex- and status-based differences appear in adulthood. We discuss the possibility of cultural buffering and dietary selectivity of females and high-status individuals. Copyright © 2012 Wiley Periodicals, Inc.

Impact of industrialization: comparative study of child health in four sites from medieval and postmedieval England (A.D. 850-1859).

Science.gov (United States)

Lewis, Mary E

2002-11-01

The morbidity and mortality profiles of 831 non-adult skeletons from four contrasting sites in medieval and postmedieval England were compared to assess whether urbanization and later industrialization, had a detrimental effect on the health of the inhabitants. Failure in the population's ability to adapt to these environments should be evident in the higher rates of mortality, retarded growth, higher levels of stress, and a greater prevalence of metabolic and infectious disease in the urban groups. Non-adult skeletons were examined from Raunds Furnells in Northamptonshire, from St. Helen-on-the-Walls and Wharram Percy in Yorkshire, and from Christ Church Spitalfields in London. Results showed that a greater number of older children were being buried at the later medieval sites and that the skeletal growth profiles of the medieval urban and rural children did not differ significantly. A comparison of the growth profiles of St. Helen-on-the-Walls (urban) and Spitalfields (industrial) showed that the Spitalfields children were up to 3 cm shorter than their later medieval counterparts. At Spitalfields, cribra orbitalia and enamel hypoplasias occurred during the first 6 months of life, and 54% of the non-adults had evidence of metabolic disease. It is argued that differences in the morbidity and mortality of non-adults from urban and rural environments did exist in the past, but that it was industrialization that had the greatest impact on child health. Environmental conditions, urban employment, socioeconomic status, and changes in weaning ages and infant feeding practices contributed to differences in health in rural, urban, and industrial environments. Copyright 2002 Wiley-Liss, Inc.

Norse agriculture in Greenland? Farming in a remote medieval landscape

DEFF Research Database (Denmark)

Henriksen, Peter Steen

The aim of the project Norse Farming in Greenland: Agriculture on the edge was to determine whether the Norse farmers actually cultivated crops in Greenland during colonisation in the Viking age and the medieval period. This was investigated by analysing macrofossils extracted from soil samples...... giving information about the local vegetation. Charred grains and threshing waste of barley was found in samples from four sites, strongly indicating that barley was cultivated in Greenland by the Norse farmers. The phosphate analyses showed no sign of any deliberate manuring of the infields as high...

Three individuals, three stories, three burials from medieval Trondheim, Norway.

Science.gov (United States)

Suppersberger Hamre, Stian; Ersland, Geir Atle; Daux, Valérie; Parson, Walther; Wilkinson, Caroline

2017-01-01

This article presents the life stories of three individuals who lived in Trondheim, Norway, during the 13th century. Based on skeletal examinations, facial reconstructions, genetic analyses, and stable oxygen isotope analyses, the birthplace, mobility, ancestry, pathology, and physical appearance of these people are presented. The stories are discussed within the relevant historical context. These three people would have been ordinary citizens, without any privileges out of the ordinary, which makes them quite rare in the academic literature. Through the study of individuals one gets a unique look into the Norwegian medieval society.

Productividad en materia seca y captura de carbono en un sistema silvopastoril y un sistema tradicional en cinco fincas ganaderas de piedemonte en el departamento de Casanare

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Estrella Cárdenas Castro

2012-12-01

Full Text Available El objetivo fue comparar, en cuanto a productividad en materia seca y captura de carbono, entre un sistema silvopastoril y un sistema tradicional en cinco fincas ganaderas de piedemonte del departamento de Casanare. En el lote experimental de cada finca se sembró una mezcla de cuatro especies de pastos, de los cuales Brachiaria brizantha fue la especie que tuvo un desarrollo exitoso en las cinco fincas, y con la cual se analizó su productividad en materia seca y captura de carbono. A los cinco meses después de la renovación de pastos en los lotes experimentales se obtuvo una productividad en materia seca entre 6,3 y 14,9 tMS/ha, y en captura de carbono entre 2,7 y 6,4 tCOT/ha; mientras que en los lotes tradicionales estuvo entre 4 y 5 tMS/ha, y en captura de carbono entre 1,7 y 2,9 tCOT/ha. A los 20 meses en los lotes experimentales se obtuvo una productividad en materia seca entre 12 y 13,7 tMS/ha, y en captura de carbono entre 4,1 y 4,5 tCOT/ha; mientras que en los lotes tradicionales estuvo entre 4,4 y 6,5 tMS/ha, y en captura de carbono entre 1,4 y 2,1 tCOT/ha. Esto indica que la renovación de praderas con pastos adecuados y el pastoreo de rotación favorecen la producción en materia seca y la captura de carbono.

Social Perception of Infertility and Its Treatment in Late Medieval Italy: Margherita Datini, an Italian Merchant’s Wife

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Jong Kuk NAM

2016-12-01

Full Text Available Because the perception of infertility in medieval Europe ranged from the extremely religious view of it as a malediction of God or the devil’s work, to the reasonable medical conception of it as a sort of disease to treat, it is very difficult to determine the general attitudes of ordinary people towards infertility. This article seeks to elucidate the common social perception of infertility and its treatment in late medieval Europe by analyzing the case of Margherita Datini, an Italian merchant’s wife who lived in the 1400s. It relies heavily on the documents left by her and her husband, Francesco Datini; the couple left many records, including letters of correspondence between them. Margherita and those around her regarded infertility not as the devil’s curse or a punishment by God but as a disease that can be cured. Margherita and her husband, Francesco, tried hard to cure their infertility. They received treatment and prescriptions from several doctors while also relying on folk remedies, religious therapies, and even magical remedies. The comparative analysis of Datini documents, medical books, and theoretical treatises or prescriptive essays by clerics suggests that the general perception of infertility in medieval Europe was located between the extremely religious and modern medical conceptions of it.

À la recherche de la senefiance… — Lecture intertextuelle des récits de rêve médiévaux // In search of the senefiance… — Intertextual study of dream scenes in medieval French texts

OpenAIRE

Linda Németh

2015-01-01

The modern reader cannot read and interpret a medieval text in the same way as the medieval reader because of remoteness in time, the distance between our cultural space and medieval cultural space. We should understand them in terms of their own context, treat all énoncés in their specific historical and socio-cultural contexts. Special attention must be paid to dream scenes in medieval French texts which are separate events from narrative structure. On the one hand, our study fo...

Interaction of pulse laser radiation of 532 nm with model coloration layers for medieval stone artefacts

Energy Technology Data Exchange (ETDEWEB)

Colson, J. [University of Vienna, Department of Physical Chemistry, A-1090 Vienna (Austria); Nimmrichter, J. [Austrian Federal Office for the Care of Monuments, Department for Conservation and Restoration, Arsenal, Objekt 15, Tor 4, A-1030 Vienna (Austria); Kautek, W., E-mail: wolfgang.kautek@univie.ac.at [University of Vienna, Department of Physical Chemistry, A-1090 Vienna (Austria)

2014-05-01

Multilayer polychrome coatings on medieval and Renaissance stone artefacts represent substantial challenges in laser cleaning. Therefore, polychromic models with classical pigments, minium (Pb{sub 2}{sup 2+}Pb{sup 4+}O{sub 4}), zinc white (ZnO), and lead white ((PbCO{sub 3}){sub 2}·Pb(OH){sub 2}) in an acrylic binder, were irradiated with a Q-switched Nd:YAG laser emitting at 532 nm. The studied medieval pigments exhibit strongly varying incubation behaviours directly correlated to their band gap energies. Higher band gaps beyond the laser photon energy of 2.3 eV require more incubative generation of defects for resonant transitions. A matching of the modification thresholds after more than four laser pulses was observed. Laser cleaning with multiple pulsing should not exceed ca. 0.05 J/cm{sup 2} when these pigments coexist in close spatial proximity.

Determination of the origin of the medieval glass bracelets discovered in Dubna (Moscow Region, Russia), using the neutron activation analysis

International Nuclear Information System (INIS)

Dmitrieva, S.O.; Frontas'eva, M.V.; Dmitriev, A.Yu.; Dmitriev, A.A.

2016-01-01

The work is dedicated to the determination of the origin of archaeological finds from medieval glass using the method of neutron activation analysis (NAA). Among such objects we can discover things not only produced in ancient Russian glassmaking workshops but also brought from Byzantium. The authors substantiate the ancient Russian origin of the medieval glass bracelets of pre-Mongol period, found on the ancient Dubna settlement. The conclusions are based on the data about the glass chemical composition obtained as a result of NAA of ten fragments of bracelets at the IBR-2 reactor, FLNP, JINR. [ru

Rosacea and contact allergy to cosmetics and topical medicaments--retrospective analysis of multicentre surveillance data 1995-2002.

Science.gov (United States)

Jappe, U; Schnuch, A; Uter, W

2005-02-01

The role of contact allergy in rosacea has rarely been investigated. In this retrospective study, 361 out of 76,697 patients tested and documented by the Information Network of Departments of Dermatology between 1995 and 2002 had rosacea. Patch tests included standard series and constituents of cosmetics and topical medicaments. 118/361 had additionally been patch tested with their own cosmetics/medicaments. Positive reactions occurred to nickel (II) sulfate in 9.3%, fragrance mix in 8.8%, thimerosal in 6.9%, Myroxylon pereirae resin in 5.9%, potassium dichromate in 4.6% and propolis in 2.8%. Whereas rosacea patients had a significantly higher risk of contact allergy to propolis compared to the remaining patients, in an age- and sex-adjusted analysis, contact allergy to nickel was significantly less frequent in this group. For Lyral, the risk was elevated, albeit not significantly. Only 2/329 patients were positive to neomycin sulfate and 1/100 to gentamicin sulfate, among the panel of (topical) antibiotics tested. Among 118 patients tested with their own products, 3 were tested to metronidazole, 1 reacting positively. Irritant or doubtful patch test reactions were provoked by various substances (vehicles, oxidants and preservatives of various creams), which might also be clinically important, considering the heightened sensitivity of rosaceous skin.

[Analysis of several key problems of good agricultural practice (GAP) of Chinese materia medica].

Science.gov (United States)

Yang, Guang; Guo, Lan-Ping; Zhou, Xiu-Teng; Huang, Lu-Qi

2016-04-01

This paper reviewed the historical background of the GAP, analyzed the development experience of five Ps (GMP, GLP, GSP, GCP, GAP), analyzed the GAP based on economic theories, and pointed out that the core problem of GAP is ignoring economic laws. Once the GAP, is a process of certification, but neither the GAP announcement could be transformed into signal transmission quality in the product market, nor consumers could recognize the difference between GAP and non-GAP herbs in the terminal market, so manufacturers lack motivation for GAP certification. In this paper, we pointed out, that the GAP certification system should be redesigned under the guidance of economics, third party certification body, supervised by drug administration organization, to certificate GAP as high quality standards, to improve signal transduction mechanism of GAP certification, and to integrate GAP with the market. Copyright© by the Chinese Pharmaceutical Association.

Voyages of a successful text. The Dialogi of Gregory the Great in Medieval Sicily (XII-XIV Century

Directory of Open Access Journals (Sweden)

Rossana Barcellona

2013-10-01

Full Text Available This essay reconstructs two “Sicilian chapters” of great success from the Dialogi by Gregorius Magnus which were enjoyed in the medieval era. These are the legend of Placido (Placido is a Benedict's young disciple mentioned in the Dialogi, which has Sicily as a background, as recounted by Pietro, Deacon of Montecassino between the XI and the XII centuries, and the Sicilian vulgarization of the work, carried out by Giovanni Campolo in the first half of the XIV century. The literary voyage of Placido and the work of Campolo are two excellent examples of the circulation and the fruition of an exemplary and authoritative text. Each highlights the complex intricacy of religion, culture and politics in the various systems of power and in the various historical settings that the medieval age explored.

Two medieval swords from the regional museum in Jagodina

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Cvetković Branislav

2009-01-01

Full Text Available The author analyzes two medieval swords (one found near Kalenić monastery and one near the Ćuprija town from the funds of the Department of Archaeology in the Regional Museum in Jagodina. He presents arguments in opposition to the typological classification existent in scholarly literature of the first one, and concludes that the both specimens most probably originate from the same workshop, as were being stamped with identical maker-marks. In the end the author draws one’s attention to circumstances of the site find of the first sword, and also points towards possible directions of research of the sacred topography of the Kalenić monastery environs.

New astronomical references in two Catalonian late medieval documents.

Science.gov (United States)

Martínez, María José; Marco, Francisco J

2014-01-01

In 2008, after 13 years of preparation, the Generalitat of Catalunya finished the publication of the 10 volumes of the Dietaris de la Generalitat de Catalunya. The Dietaris, as well as a closely related source, the llibre de Jornades 1411/1484 de Jaume Safont, cover the period of 1411 to 1539. In this article, we examine astronomical references contained in these two sources, and place them in their historical context. Our main focus lies on astronomical phenomena that have not previously been published in the astronomical literature. In fact, relatively few astronomical records are accessible in Spanish medieval and early modern history, and our paper intends to fill this gap partially.

Support for global climate reorganization during the ''Medieval Climate Anomaly''

Energy Technology Data Exchange (ETDEWEB)

Graham, N.E. [Hydrologic Research Center, San Diego, CA (United States); Scripps Institution of Oceanography, La Jolla, CA (United States); Ammann, C.M. [National Center for Atmospheric Research, Boulder, CO (United States); Fleitmann, D. [University of Bern, Institute of Geological Sciences, Bern (Switzerland); University of Bern, Oeschger Centre for Climatic Change Research, Bern (Switzerland); Cobb, K.M. [Georgia Institute of Technology, Atlanta, GA (United States); Luterbacher, J. [Justus-Liebig-University, Giessen (Germany)

2011-09-15

Widely distributed proxy records indicate that the Medieval Climate Anomaly (MCA; {proportional_to}900-1350 AD) was characterized by coherent shifts in large-scale Northern Hemisphere atmospheric circulation patterns. Although cooler sea surface temperatures in the central and eastern equatorial Pacific can explain some aspects of medieval circulation changes, they are not sufficient to account for other notable features, including widespread aridity through the Eurasian sub-tropics, stronger winter westerlies across the North Atlantic and Western Europe, and shifts in monsoon rainfall patterns across Africa and South Asia. We present results from a full-physics coupled climate model showing that a slight warming of the tropical Indian and western Pacific Oceans relative to the other tropical ocean basins can induce a broad range of the medieval circulation and climate changes indicated by proxy data, including many of those not explained by a cooler tropical Pacific alone. Important aspects of the results resemble those from previous simulations examining the climatic response to the rapid Indian Ocean warming during the late twentieth century, and to results from climate warming simulations - especially in indicating an expansion of the Northern Hemisphere Hadley circulation. Notably, the pattern of tropical Indo-Pacific sea surface temperature (SST) change responsible for producing the proxy-model similarity in our results agrees well with MCA-LIA SST differences obtained in a recent proxy-based climate field reconstruction. Though much remains unclear, our results indicate that the MCA was characterized by an enhanced zonal Indo-Pacific SST gradient with resulting changes in Northern Hemisphere tropical and extra-tropical circulation patterns and hydroclimate regimes, linkages that may explain the coherent regional climate shifts indicated by proxy records from across the planet. The findings provide new perspectives on the nature and possible causes of the MCA

[Paleopathological skeleton findings. Macroscopical and radiographical studies of 364 individuals from a medieval graveyard].

Science.gov (United States)

Ittrich, H; Kleibscheidel, C; Nizze, H

2004-03-01

Paleopathological examinations can give an idea of diseases and living conditions in ancient populations. An archaeological collection of 364 late medieval/early modern skeletons from the thirteenth to eighteenth centuries, excavated from a church cemetery in the Rostock town center, was examined palaeopathologically. The type and frequency of certain diseases within this north German urban population are described. The majority of the skeletons were from adults with a remarkably low percentage of children. Skeletal malformations (e.g. gap formations of the spinal column) were not abnormally represented. With the exception of single individuals, metabolic disorders or unusual infectious diseases could not be diagnosed. Degenerative diseases often found at the joints and the spinal column showed substantially lower prevalences in comparison with reference rural populations. Individual cases of benign and rare malignant neoplasms could be documented. Traumatic injuries as well as dental pathological changes were rare. In summary it can be concluded that the individuals buried here belonged to a better social class within the medieval population of Rostock.

Identificación de dos formas polimórficas cristalinas de clopidogrel bisulfato en materia prima farmacéutica

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German Leonardo Madrigal Redondo

Full Text Available Introducción: el clopidogrel bisulfato existe en numerosas formas cristalinas, que varían en su estabilidad fisicoquímica, por lo que algunas de estas formas, patentadas o no, son útiles en la fabricación de medicamentos. Objetivo: identificar las formas cristalinas existentes en dos muestras de clopidogrel bisulfato materia prima comercializadas para la fabricación de medicamentos y el estado de pureza de ambas muestras. Métodos: las muestras de materia prima se obtuvieron de una industria nacional. Se examinaron mediante técnicas analíticas avanzadas como difracción de rayos X, calorimetría diferencial de barrido, termogravimetría y espectroscopia infrarroja. Se compararon los valores encontrados con los del estado del arte reconocidos en la literatura revisada para el clopidogrel bisulfato materias primas y tomados como referencia. Resultados: se obtuvieron los difractogramas, termogramas y espectros de absorción correspondientes a las muestras analizadas. Se utilizó el software TA Universal Analysis para obtener el porcentaje de descomposición, punto de fusión y picos identificadores en las muestras. Conclusiones: la muestra 1 contiene la forma cristalina I del bisulfato de clopidogrel, que no es pura ya que existe una banda característica de la presencia de contaminación con la forma cristalina II. La muestra 2 corresponde a la forma cristalina II del producto en forma pura.

Archaeometric investigation of medieval Bulgarian glasses and sgraffito ceramics by neutron activation analysis

International Nuclear Information System (INIS)

Dzhingova, R.; Kulev, I.

1985-01-01

Instrumental neutron activation analysis was used to determine the content of Au, Ba, Ca, Ce, Cl, Cr, Co, Cs, Cu, Eu, Fe, Hf, La, Lu, Mn, Na, Rb, Sc, Sm, Sr, Ta, Tb, Th, Ti, U, Sb, V and Yb in glass samples excavated from medieval glassworkshops in Pliska and Preslav and in 20 glass finds from Preslav. Sgraffito ceramic samples excavated in Veliko Tarnovo were also analysed and the elements Al, As, Au, Ba, Br, Ce, Co, Cr, Cs, Dy, Eu, Fe, Hf, K, La, Lu, Mg, Mn, Na, Nd, Rb, Sb, Sc, Si, Sm, Ta, Tb, Th, Ti, U, V and Yb were determined. In order to localize the production site of the archaeological finds, the results from the analysis were subjected to cluster analysis, and stepwise discriminant analysis using the program package BMDP. A variety of the production of the medieval glass workshop in Preslav was identified and evaluated. It was proved that a part of the sgraffito ceramics samples have been produced in one and the same place and that the chemical composition might be successfully used to differentiate between the production of two workshops

Karg S., D.E. Robinson (2002): Secondary food plants from medieval sites in Denmark: fruits, nuts, vegetables, herbs and spices. In: K. Viklund, R. Engelmark (eds.) Nordic Archaeobotany-NAG 2000 in Umeå.

DEFF Research Database (Denmark)

Karg, Sabine

2002-01-01

Secondary food plants from medieval sites in Denmark: fruits, nuts, vegetables, herbs and spices.......Secondary food plants from medieval sites in Denmark: fruits, nuts, vegetables, herbs and spices....

From Egypt to Umbria: Jewish Women and Property in the Medieval Mediterranean

OpenAIRE

Frank, Karen A

2010-01-01

This article compares the financial activities of medieval Jewish women in Italy and the Mediterranean. Contrary to Jewish legal tradition, which curtailed women’s financial autonomy, by the later Middle Ages communities across the region increasingly allowed women to manage their own dotal property, inherit property from a variety of sources, and engage in loan banking. An examination of the historical developments of some Jewish communities in Egypt, Spain, and central Italy suggests that t...

Medieval Stars in Melk Abbey

Science.gov (United States)

Beck, P. G.; Zotti, G.

2012-05-01

Melk Abbey, a marvel of European high baroque architecture, is one of the most frequently visited tourist attractions in Austria, attracting 450 000 visitors each year. The monastery's museum presents selected aspects of Benedictine life in Melk since the monastery's foundation in 1089. After the church, the library is the second-most important room in a Benedictine monastery. Due to the wide scientific interests and contacts of the medieval monks, these libraries also contain manuscripts on mathematics, physics and astronomy. In 2009, the International Year of Astronomy (IYA2009), the annual library exhibition was fully dedicated to astronomical manuscripts and early prints from the past 1000 years. Following earlier research work on astronomical manuscripts in Melk's library, we were invited to organise the exhibition. In addition, we also presented a lecture series and provided more background in an accompanying book. Because of positive feedback from the visitors, the exhibition was extended until March 2011. In the two years of its duration, the exhibition was seen by more than 900 000 visitors. In this article, we describe the background to the scientific project, how the exhibition was organised and lessons learned from this project.

Hidden library : Visualizing fragments of medieval manuscripts in early-modern bookbindings with mobile macro-XRF scanner

NARCIS (Netherlands)

Duivenvoorden, Jorien R.; Käyhkö, Anna; Kwakkel, Erik; Dik, J.

2017-01-01

This experiment demonstrates the large potential of macro-XRF imaging for the visualization of fragments of medieval manuscripts hidden in early-modern bookbindings. The invention of the printing press in the fifteenth century made manuscripts obsolete and bookbinders started recycling their

Finger of a saint, thumb of a priest: medieval relics in the Diocese of Turku, and the archaeology of lived bodies

Directory of Open Access Journals (Sweden)

Visa Immonen

2011-01-01

Full Text Available The relics of Turku Cathedral are remains belonging to the bodies of holy persons, different from ours, even today, although the cathedral is the see for the archbishop of the Evangelical Lutheran Church of Finland, and relics are not on public display. Among the relics of the cathedral, there is a fragment of a radius, which according to its authentica, belongs to St Henry. Relics and reliquaries were in the core of medieval piety, and the cult of saints had infused throughout the society. Due to their central position in culture, relics offer glimpses at a range of material, social and cultural phenomena related to medieval embodiment.The Department of Archaeology at the University of Turku began to study the finger relic of St Eric and other items in the assemblage of Turku Cathedral in 2007. Relics and reliquaries are being opened and documented and organic as well as inorganic samples are being taken for a range of scientific analyses. So far the project has concentrated on building a chronological chart of individual artefacts. The majority of the relics date to the fourteenth century, although much more recent datings have also been obtained. The challenge of the project is not to stop when a better understanding of materials, their origins and age has been accomplished, but to use the results as a steppingstone into a study of the practices of medieval relic veneration. Medieval bodies and those material processes which authenticate relics, or distinguish saints’ bodies from other human remains, are thus at the heart of this article discussing embodiment.

Aristotle's carp as Claretus' bird comor? Tracing the origin of one medieval term

Czech Academy of Sciences Publication Activity Database

Šedinová, Hana

-, č. 2 (2016), s. 111-123 ISSN 0567-8269 R&D Projects: GA MŠk(CZ) LD13043 Institutional support: RVO:67985955 Keywords : ancient and medieval zoology * Latin lexicography * Aristoteles * Aristoteles Latinus * Michael Scotus * Thomas of Cantimpré * Claretus * carp * komor * comor Subject RIV: AI - Linguistics http://www.karolinum.cz/ink2_stat/index.jsp?include=AUC_clanek&id=2668&casopis=94&zalozka=0&predkl=0

Arqueología Medieval en Guipúzcoa. Estado actual y perspectivas de futuro.

Directory of Open Access Journals (Sweden)

M. Mercedes Urteaga Artigas

1990-01-01

Full Text Available La Arqueología Medieval en Guipúzcoa tiene una larga trayectoria. Iniciada a principios de siglo, las actuaciones se han sucedido hasta el presente, de manera intermitente. En la actualidad presenta una evolución acelerada, ligada, sobre todo, a las intervenciones de salvamento. El futuro de la misma, parece especialmente vinculado a este tipo de actuaciones arqueológicas.

Acerca de la evolución semántica de los adjetivos relacionales en español medieval y clásico

OpenAIRE

Serradilla Castaño, Ana

2010-01-01

En este artículo se analiza la evolución semántica que sufren algunos adjetivos relacionales en español medieval y, sobre todo, en español clásico. Se trata de adjetivos como ageno, carnal, divino, mortal, criminal…, que en la época medieval funcionan como relacionales con el valor de ‘relativo a’ ‘perteneciente a’, ‘procedente de’, etc., independientemente del contexto sintáctico en que se encuentren: anteposición, posposición, construcciones superlativas… Frente a esta situación, a part...

Medieval and early modern approaches to fractures of the proximal humerus

DEFF Research Database (Denmark)

Brorson, S.

2010-01-01

The diagnosis and management of complex fractures of the proximal humerus have challenged surgical practitioners and medical writers since the earliest recorded surgical texts. Current knowledge of fractures of the proximal humerus has been obtained through pathoanatomical and biomechanical studies...... within the last two centuries. However, the historical preconditions for this development have not been studied. This paper reviews written sources from the fall of the Roman Empire to the late eighteenth century. Medieval and early modern writers mainly rely on the Hippocratic writings De Fracturis...

'Fro Paris to Inglond'? The danse macabre in text and image in late-medieval England

NARCIS (Netherlands)

Oosterwijk, Sophia

2009-01-01

This thesis examines the character, spread, development and influence of the Dance of Death or danse macabre theme in late-medieval England within its literary, socio- and art-historical context. It traces the origins of the theme and, following the deaths in 1422 of the English king Henry V and

Druids, deer and ‘words of power’: coming to terms with evil in medieval Ireland

NARCIS (Netherlands)

Borsje, J.; van Doorn-Harder, N.; Minnema, L.

2008-01-01

This contribution describes what is understood by evil, as perceived within Irish medieval texts, both by the authors and by the groups described in the texts. It attempts to include the points of view of possible audiences or readers of the texts as well. The definition of evil employed here thus

Wrestling with Stephen and Matilda: Planning Challenging Enquiries to Engage Year 7 in Medieval Anarchy

Science.gov (United States)

McDougall, Hannah

2013-01-01

McDougall found learning about Stephen and Matilda fascinating, was sure that her pupils would also and designed an enquiry to engage them in "the anarchy" of 1139-1153 AD. Pupils enjoyed exploring "the anarchy" and learning about it enhanced their knowledge and understanding of the medieval period considerably. However,…

Medieval capital markets. Markets for renten between state formation and private investment in Holland (1300-1550)

NARCIS (Netherlands)

Zuijderduijn, C.J.

2007-01-01

The book is structured as follows. Chapter 1 introduces medieval Holland as a significant entity for institutional-economic development by discussing how the state created a county wide societal structure. As a proto-territorial state Holland had a uniform judiciary, a government apparatus that gave

Early Medieval silver pearl from Lumbe's garden cemetery at Prague Castle: Composition, manufacture, deterioration, and conservation

Czech Academy of Sciences Publication Activity Database

Děd, J.; Ottenwelter, Estelle; Šejvlová, Ludmila

2016-01-01

Roč. 61, č. 3 (2016), s. 174-183 ISSN 0039-3630 R&D Projects: GA ČR GAP405/12/2195 Institutional support: RVO:67985912 Keywords : medieval jewellery * Lumbe's Garden * archaeometry Subject RIV: AC - Archeology, Anthropology, Ethnology Impact factor: 0.578, year: 2016

Studies on tofts, peasants and hierarchies in medieval rural Denmark - some comments from an archaeological perspective

DEFF Research Database (Denmark)

Kristiansen, Mette Svart

2013-01-01

A classical starting point for an archaeological discussion of hierarchy in Danish settlement research is the toft, particularly its size and position in the spatial arrangement of the medieval village. The main concern of this article is to identify and discuss related problems, in particular...

Substance and materiality? The archaeology of Talensi medicine shrines and medicinal practices.

Science.gov (United States)

Insoll, Timothy

2011-08-01

Talensi materia medica is varied, encompassing plant, mineral, and animal substances. Healing, medicines, and medicinal practices and knowledge can be shrine-based and linked with ritual practices. This is explored utilising ethnographic data and from an archaeological perspective with reference to future possibilities for research both on Talensi medicine and, by implication, more generally through considering the archaeology of Talensi medicine preparation, use, storage, spread, and disposal. It is suggested that configuring the archaeology of medicine shrines and practices more broadly in terms of health would increase archaeological visibility and research potential.

Concepto y trascendencia del derecho de aprovechamiento en materia de aguas (Propiedad y Aprovechamiento

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Enrique Guerra Daneri

2013-12-01

Full Text Available La disciplina de las aguas se encuentra estructurada jurídicamente, sólo en base a dos derechos: el de propiedad y el de aprovechamiento. La caracterización que posee el agua como cosa, impide que puedan ejercerse otros derechos sobre ella.El punto de partida para explicar este fenómeno, radica en que el agua responde a dos hechos técnicos que ofician como fuente material o factor de calificación jurídica: el principio de territorialidad y la unidad del ciclo hidrológico. Estos dan motivo a su comportamiento universal y en ellos se asienta su disciplina, más allá de la regulación particular que cada derecho positivo quiera desarrollar, imponiendo una política en la materia.  En síntesis, el agua es un bien cuyas particularidades determinan que en definitiva, el derecho de propiedad sea desplazado en su trascendencia patrimonial por otro derecho que ocupa su lugar en jerarquía e individualidad: el derecho de aprovechamiento. Sin embargo y a pesar de los sólidos fundamentos que lo sustentan, la identidad de este derecho parece todavía opacada por los reflejos de una propiedad, que en materia de aguas, es inoperante.       

IMPACTO DEL MATERIAL RECICLADO EN LOS INVENTARIOS DE MATERIAS PRIMAS DE UNA EMPRESA MANUFACTURERA

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Guillermo Antonio Salinas López

Full Text Available En el presente trabajo, se diseña un modelo de dinámica de sistemas, que junto con algunos indicadores de gestión, se usan para dimensionar el impacto del uso del material reciclado en una industria. Lo anterior, con el fin de proveer mejores elementos en la toma de decisiones sobre la gestión de las existencias de materias primas. Para esto se hace una revisión de los principales elementos que inciden en el esquema productivo de una empresa caso de estudio, con la cual se obtiene, una caracterización de la industria y posterior configuración de la estructura y las relaciones del sistema, para modelar y simular utilizando el software Vensim DSS. A partir de dichas simulaciones, se revisa el comportamiento del sistema, así como las variaciones que presenta, ante diferentes escenarios y cambios en sus parámetros más relevantes. Al final, se obtiene un modelo que ilustra el comportamiento de los niveles de inventario de distintos tipos de materiales, así como los valores de algunos indicadores logísticos y energéticos, que revelan el importante trabajo por realizar, en materia de reciclaje en la región del Valle del Cauca y Colombia en general.

Investigation of medieval ceramics from Ras by physicochemical methods

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Zindović Nataša D.

2008-01-01

Full Text Available Although early medieval Serbian ceramic is well described by the archeologists and historians, knowledge of the Balkan ceramic production is still limited. Archaeometric study of ceramics provenance, technology of preparation and used pigments as well as influence of neighboring countries and specific characteristics of different workshops has never been performed so far. The detailed knowledge of the micro-chemical and micro-structural nature of an archaeological artifact is critical in finding solutions to problems of restoration, conservation, dating and authentication in the art world. In this work we present results of systematic investigation of pottery shards from archeological site Ras. The term Ras, which signifies both the fortress and the region encompassing the upper course of Raška River, used to be the center of the medieval Serbian state. Both the ceramic body and the polychromatic glaze of the artifacts were studied by a multianalitical approach combining optical microscopy (OM, FT-IR spectroscopy and X-ray fluorescence (XRF. Mineralogical composition of pottery shards has been determined combining results obtained by FT-IR spectroscopy, after deconvolution of the spectra, and XRPD analysis. Firing temperature has been estimated based on the mineralogical composition and positions of Si-O stretching (-1000 cm-1 and banding (-460 cm-1 vibrations. Investigated samples have been classified into two groups based on the mineralogical composition, cross sections and firing temperature. Larger group consists of samples of fine-grained, homogeneous ceramics with firing temperatures bellow 800 °C which indicates imported products. Second, smaller group consists of inhomogeneous ceramics with firing temperatures between 850 and 900 °C produced in the domestic workshops. The obtained results will be used to build up a national database for the compositions of bodies, glazes and pigments.

The wine trade, piracy and maritime contract law in late medieval Southampton

OpenAIRE

Pamuk, Fatih

2014-01-01

Ankara : The Department of History, İhsan Doğramacı Bilkent University, 2014. Thesis (Master's) -- Bilkent University, 2014. Includes bibliographical references leaves 102-105. In late medieval Southampton, wine was a commodity, which was extensively traded, and quite precious to the pirates of the English Channel because it was easy to sell and the vessels loaded with wine had less protection than the ships of precious metals. Therefore, increase of wine trade in the late m...

Post-Mortem Projections: Medieval Mystical Resurrection and the Return of Tupac Shakur

OpenAIRE

Spencer-Hall, A.

2012-01-01

Medieval hagiographies abound with tales of post-mortem visits and miracles by saints. The saint was a powerful religious individual both in life and in death, a conduit of divine grace and lightning rod for Christian fervour. With her post-mortem presence, the presumptive boundary between living and dead, spirit and flesh, is rent apart: showing the reality of the hereafter and shattering the fantasies of the mortal world. The phenomenon of a glorified individual returning to ...

Physical education of the medieval knight La educación física del caballero medieval

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Buenaventura DELGADO

2013-09-01

Full Text Available The medieval knight was required to perform the same physical exercices and have the same capabilities as Spartan, Athenian and Roman soldiers. They had to be agile, strong, fast and able to use weapons on foot as on horseback. To be pysically fit was as important as knowing history as explained by tutors and sung by jugglers in moments of leisure during which they learnt of legends, nationals heroes and the paradigms that distinguish nations. All the heroes praised through generations provide models shaped the collective personality of entire peoples. San Isidoro de Sevilla, Ramón Llull, King Alfonso X the Wise and Don Juan Manuel were the principal writers to exalt the figure of the knight and his education. During the XII, XIII, XIV and XV centuries and including the Renaissance, there were exhibitions of physical games, during which knights sought fame and fortune: jousts, tournaments, staged games, games using canes and processions of arms called «pasos honrosos» were undertaken with popular enthusiasm in Western and central Europe in the Byzantine Empire and throughout the Moslem world.Los ejercicios y habilidades físicas exigidos al caballero medieval fueron semejantes a los que se pedían al militar espartano, ateniense y romano. Debían ser ágiles, fuertes, rápidos y diestros en el manejo de las armas a pie y a caballo. Tan importante como una buena forma física era conocer la Historia cantada por ayos y juglares en los momentos de ocio, a través de la cual se familiarizaban con las tradiciones, leyendas, héroes nacionales y los paradigmas que distinguían a un pueblo de otro. El abanico de héroes alabados y ensalzados de generación en generación eran otros tantos modelos destinados a troquelar la personalidad colectiva de cada pueblo. San Isidoro de Sevilla, Ramón Llull, el rey Alfonso X el Sabio y Don Juan Manuel son los principales escritores interesados en ensalzar la figura del caballero y su educación. En los siglos

El suelo y la materia orgánica en la provisión de servicios ecosistémicos

OpenAIRE

Marañón, Teodoro

2017-01-01

Conferencia impartida en el Curso "Materia orgánica del suelo: metodología para su análisis y su incidencia en el medioambiente y el cambio climático". Coordinado por José María de la Rosa Arranz. IRNAS, CSIC, 16-19 octubre 2017.

Making computers noble. An experiment in automatic analysis of medieval texts

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Andrea Colli

2016-02-01

Full Text Available L’analisi informatica di testi filosofici, la creazione di database, ipertesti o edizioni elettroniche non costituiscono più unicamente una ricerca di frontiera, ma sono da molti anni una risorsa preziosa per gli studi umanistici. Ora, non si tratta di richiedere alle macchine un ulteriore sforzo per comprendere il linguaggio umano, quanto piuttosto di perfezionare gli strumenti affinché esse possano essere a tutti gli effetti collaboratori di ricerca. Questo articolo è concepito come il resoconto di un esperimento finalizzato a documentare come le associazioni lessicali di un gruppo selezionato di testi medievali possa offrire qualche suggerimento in merito ai loro contenuti teorici. Computer analysis of texts, creation of databases hypertexts and digital editions are not the final frontier of research anymore. Quite the contrary, from many years they have been representing a significant contribution to medieval studies. Therefore, we do not mean to make the computer able to grasp the meaning of human language and penetrate its secrets, but rather we aim at improving their tools, so that they will become an even more efficient equipment employed in research activities. This paper is thought as a sort of technical report with the proposed task to verify if an automatic identification of some word associations within a selected groups of medieval writings produces suggestions on the subject of the processed texts, able to be used in a theoretical inquiry.

Finding the Sacred Direction: Medieval Books on the Qibla

Science.gov (United States)

Rius, M.

2009-08-01

Medieval Islamic scholars wrote a great number of books on the qibla, the Sacred Direction. These books had a huge readership and provided instructions for finding the direction of Mecca by either exact or approximate means. In principle, the qibla was a purely religious subject, but in practice its determination required the use of astronomy as an applied science. As so often, religion and politics had many points of contact and, in this case, it was generally political considerations that prevailed. Finally, the analysis of nautical charts can offer new perspectives. As yet, modern scholarship has not established the link between this area of study and the classical literature on this subject.

Isidoro de Sevilla: el banco de datos medieval

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Américo Abad

2014-10-01

Full Text Available San Isidoro de Sevilla, el Doctor egregius de Ios siglos VI y VII, constituye una referencia medieval de suma importancia y en varios aspectos. Su obra enciclopédica, su pensamiento jurídico y filosófico, su conducción de los asuntos políticos, su apología de la iglesia como institución ecuménica, cuando apenas se dibujaban los primeros rasgos -impalpables casi - de la sociedad civil y del estado y la organizacJón del saber y del conocimiento llegados a su tiempo.Contenido: Presentación. El proyecto enciclopédico. Universo y sistema. Etimologías y otros textos. La ley y el gobierno. La filosofía. Comunidad y comunidades. Consideraciones finales

Una perspectiva internacional sobre la formación en materia de seguridad y salud en el trabajo

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Félix Martín Daza

Full Text Available El presente artículo tiene el propósito de explorar algunos de los retos más importantes de la formación en la seguridad y salud en el trabajo de los diferentes grupos interesados, así como para presentar los lineamientos de la Organización Internacional del Trabajo en esta materia.

An Introduction to the Medieval English: The Historical and Literary Context, Traces of Church and Philosophical Movements in the Literature

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Esmail Zare Behtash

2017-02-01

Full Text Available The Transition from Greek to medieval philosophy that speculated on religion, nature, metaphysics, human being and society was rather a rough transition in the history of English literature. Although the literature content of this age reflected more religious beliefs, the love and hate relationship of medieval philosophy that was mostly based on the Christianity with Greek civilization was exhibited clearly. The modern philosophical ideologies are the continuation of this period’s ideologies. Without a well understanding of the philosophical issues related to this age, it is not possible to understand the modern ones well. The catholic tradition as well as the religious reform against church called Protestantism was organized in this age. In Medieval Period, philosophy and theoretical thoughts related to the Christianity were well-organized and the philosophy, science and theoretical thoughts served religion. Philosophy had different forms and orientations in various stages of this period. One of these philosophical thoughts was the Augustinian philosophy which was strongly in favor of church with its different practices and styles. It used Platonic and Neo-Platonic traditions to prove that faith is the result of divine dispensations, not the result of human will power and wisdom. On the other hand, according to Aquinas, we experience different types of the effects that existed in the world around us. He believed that we assign an effective cause to each effect we experienced around us. Additionally, he claimed that reasoning was the only way to reach the real faith. In fact, philosophy of Medieval Period attempted to prove that religious assertions and ideologists were in search of matching their philosophical beliefs with the beliefs of Christianity. Christianity as the dominant factor in Middle English Literature helped English to be stablished as a literary language.

La sciencia theorica speculativa en la construcción gótica. El promotor eclesiástico de la catedral medieval

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Lluis i Ginovart, Josep

2014-06-01

Full Text Available The construction of Gothic cathedrals can be seen as a transfer of knowledge between ecclesiastical figures the bishop and Chapter, and medieval architect. The beauty of the cathedral depended on the practica of medieval mason, versus the teorica of the church promoter. An example of this is the example of mainstreaming, the one of the construction of the Cathedral of Tortosa. Metrology and proportion of the architecture of the cathedral, derived directly from the philosophical sources of the Gothic order. The main authors of reference are identified in the chapter library; Augustine ACTo 20, Calcidius and Capella ACTo nº 80, Macrobius ACTo 236. This has allowed us to establish contact points between knowledge of the promoter and the gothic builder.La construcción de las catedrales góticas puede considerarse como un trasvase de conocimiento entre las figuras eclesiásticas del obispo y Capítulo, y el arquitecto medieval. La belleza de la catedral dependía de la practica del constructor medieval, y de la teorica de sus promotores. Una muestra de esta transversalidad es el ejemplo de la construcción de la catedral de Tortosa. La metrología y la proporción de la arquitectura de la catedral, emanan directamente de las fuentes filosóficas del orden gótico. Los principales autores de referencia están identificados en su biblioteca capitular: San Agustín (ACTo 20, Calcidio y Capella (ACTo nº 80 y Macrobio (ACTo 236. Esta circunstancia ha permitido establecer unos puntos de contacto entre los saberes del promotor y del constructor góticos.

Charlemagne's summit canal: an early medieval hydro-engineering project for passing the Central European Watershed.

Science.gov (United States)

Zielhofer, Christoph; Leitholdt, Eva; Werther, Lukas; Stele, Andreas; Bussmann, Jens; Linzen, Sven; Schneider, Michael; Meyer, Cornelius; Berg-Hobohm, Stefanie; Ettel, Peter

2014-01-01

The Central European Watershed divides the Rhine-Main catchment and the Danube catchment. In the Early Medieval period, when ships were important means of transportation, Charlemagne decided to link both catchments by the construction of a canal connecting the Schwabian Rezat and the Altmühl rivers. The artificial waterway would provide a continuous inland navigation route from the North Sea to the Black Sea. The shortcut is known as Fossa Carolina and represents one of the most important Early Medieval engineering achievements in Europe. Despite the important geostrategic relevance of the construction it is not clarified whether the canal was actually used as a navigation waterway. We present new geophysical data and in situ findings from the trench fills that prove for the first time a total length of the constructed Carolingian canal of at least 2300 metres. We have evidence for a conceptual width of the artificial water course between 5 and 6 metres and a water depth of at least 60 to 80 cm. This allows a crossing way passage of Carolingian cargo scows with a payload of several tons. There is strong evidence for clayey to silty layers in the trench fills which reveal suspension load limited stillwater deposition and, therefore, the evidence of former Carolingian and post-Carolingian ponds. These findings are strongly supported by numerous sapropel layers within the trench fills. Our results presented in this study indicate an extraordinarily advanced construction level of the known course of the canal. Here, the excavated levels of Carolingian trench bottoms were generally sufficient for the efficient construction of stepped ponds and prove a final concept for a summit canal. We have evidence for the artificial Carolingian dislocation of the watershed and assume a sophisticated Early Medieval hydrological engineering concept for supplying the summit of the canal with adequate water.

The modern enterprise – successor of business organization forms in ancient Rome and medieval Europe

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Anca Pacala

2016-03-01

Full Text Available In recent years, researchers and practitioners are increasingly interested in the role and influence of the forms of business organization on the economy and society. Interpretations of the role of companies in the modern period, ranging from enthusiastic support (as the most important invention of capitalism, an explanation of the Western civilization’s expansion to moderate and often critical positions, where the company is seen as a solution, not necessarily optimal, to market imperfections. On the other hand, we often ponder upon the explanation of political, administrative and infrastructural success of ancient Rome: the state or the enterprise (the private initiative? Closer to our time, we rediscover with amazement that the "dark" Middle Ages are not at all dark and lacking in progress, at least in terms of capitalist organization and logic. The development of trade in the two poles of medieval Europe (the Mediterranean and the BaltoScandinavian area, of industry and trade in the North-Western quadrant (Flanders and neighbouring regions, was concurrent with the improvement of organizational forms of business, with the diversity and flexibility of entrepreneurial or even corporate frameworks. Of course, the study of historical sources (ancient or medieval cannot provide direct answers or solutions to the questions of modern society, because the challenges of today are rather different to those of the past. On the other hand, understanding history can help companies to build a more complete and a wiser enterprise functionality and role in the modern society, to reformulate the questions and to find new solutions. Our paper, with a clear juridical perspective on economic history, focuses on the organization of firms in ancient Rome and medieval Europe, tries to provide examples, useful interpretations and diverse solutions to the problems of contemporary society and economy.

Citrus medica: nutritional, phytochemical composition and health benefits - a review.

Science.gov (United States)

Chhikara, Navnidhi; Kour, Ragni; Jaglan, Sundeep; Gupta, Pawan; Gat, Yogesh; Panghal, Anil

2018-04-25

Citrus medica (Citron) is an underutilized fruit plant having various bioactive components in all parts of the plant. The major bioactive compounds present are iso-limonene, citral, limonene, phenolics, flavonones, vitamin C, pectin, linalool, decanal, and nonanal, accounting for several health benefits. Pectin and heteropolysachharides also play a major role as dietary fibers. The potential impact of citron and its bioactive components to prevent or reverse destructive deregulated processes responsible for certain diseases has attracted different researchers' attention. The fruit has numerous nutraceutical benefits, proven by pharmacological studies; for example, anti-catarrhal, capillary protector, anti-hypertensive, diuretic, antibacterial, antifungal, anthelmintic, antimicrobial, analgesic, strong antioxidant, anticancerous, antidiabetic, estrogenic, antiulcer, cardioprotective, and antihyperglycemic. The present review explores new insights into the benefits of citron in various body parts. Throughout the world, citron has been used in making carbonated drinks, alcoholic beverages, syrup, candied peels, jams, marmalade, cordials, and many other value added products, which suggests it is an appropriate raw material to develop healthy processed food. In the present review, the fruit taxonomical classification, beneficial phytochemicals, antioxidant activities, and health benefits are discussed.

Effects of dentin on the antimicrobial properties of endodontic medicaments.

Science.gov (United States)

Haapasalo, Markus; Qian, Wei; Portenier, Isabelle; Waltimo, Tuomas

2007-08-01

Successful treatment of apical periodontitis is dependent on the elimination of the infective microflora from the necrotic root canal system. Antimicrobial irrigating solutions and other locally used disinfecting agents and medicaments have a key role in the eradication of the microbes. While most if not all presently used disinfecting agents rapidly kill even the resistant microbes when tested in vitro in a test tube, the effectiveness of the same agents is clearly weaker in the in vivo conditions. Recent studies have given valuable information about the interaction of endodontic disinfecting agents with dentin and other compounds present in the necrotic root canal. As a result of such interactions the antimicrobial effectiveness of several of our key disinfectants may be weakened, or even eliminated under certain circumstances. Different disinfectants show different sensitivity to the action by the various potential inactivators, such as dentin, serum proteins, hydroxyapatite, collagen derived from different sources, and microbial biomass. This review is a summary of our present knowledge of the mostly negative interactions between endodontic disinfecting agents and the various compounds present in the root canal environment.

Paleoparasitological Findings in Medieval and Early Modern Archaeological Deposits from Hradební Street, Chrudim, Czech Republic

Czech Academy of Sciences Publication Activity Database

Bartošová, L.; Ditrich, Oleg; Beneš, J.; Frolík, Jan; Musil, J.

2011-01-01

Roč. 2, č. 1 (2011), s. 27-38 ISSN 1804-848X Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z80020508 Keywords : paleoparasitology * medieval town * cesspit * helmints * hygiene Subject RIV: AC - Archeology, Anthropology, Ethnology http://www.iansa.eu/papers/IANSA-2011-01-bartosova.pdf

Environmental imperatives reconsidered: demographic crises in western North America during the medieval climatic anomaly.

Science.gov (United States)

Jones, T L; Brown, G M; Raab, L M; McVickar, J L; Spaulding, W G; Kennett, D J; York, A; Wlaker, P L

1999-04-01

Review of late Holocene paleoenvironmental and cultural sequences from four regions of western North America show striking correlations between drought and changes in subsistence, population, exchange, health, and interpersonal violence during the Medieval Climatic Anomaly (A.D. 800-1350). While ultimate causality is difficult to identify in the archaeological record, synchrony of the environmental and cultural changes and the negative character of many human responses--increased interpersonal violence, deterioration of long-distance exchange relationships, and regional abandonments--suggest widespread demographic crises caused by decreased environmental productivity. The medieval droughts occurred at a unique juncture in the demographic history of western North America when unusually large populations of both hunter-gathers and agriculturalists had evolved highly intensified economies that put them in unprecedented ecological jeopardy. Long-term patterns in the archaeological record are inconsistent with the predicted outcomes of simple adaptation or continuous economic intensification, suggesting that in this instance environmental dynamics played a major role in cultural transformations across a wide expanse of western North America among groups with diverse subsistence strategies. These events suggest that environment should not be overlooked as a potential cause of prehistoric culture change.

Post-Mortem Projections: Medieval Mystical Resurrection and the Return of Tupac Shakur

OpenAIRE

Spencer-Hall, Alicia

2012-01-01

Medieval hagiographies abound with tales of post-mortem visits and miracles by saints. The saint was a powerful religious individual both in life and in death, a conduit of divine grace and lightning rod for Christian fervour. With her post-mortem presence, the presumptive boundary between living and dead, spirit and flesh, is rent apart: showing the reality of the hereafter and shattering the fantasies of the mortal world. The phenomenon of a glorified individual returning to a worshipful co...

Prestatiekenmerken van de bepaling van As, Cd, Pb en Hg in voeding en biologisch materiaal met ICP-MS en AFS

NARCIS (Netherlands)

Velde-Koerts T van der; Bom CM; LAC

1999-01-01

Een ICP-MS-methode werd ontwikkeld voor de bepaling van As, Cd en Pb in salpeterzuur-destruaten van voeding en biologisch materiaal. De methode werd geoptimaliseerd op basis van minimale spectrale storingen en matrixeffecten met behulp van correctieformules, interne standaarden en

An early medieval symbol carved on a tree trunk. Pathfinder or territorial marker?

Czech Academy of Sciences Publication Activity Database

Dreslerová, Dagmar; Mikuláš, Radek

2010-01-01

Roč. 84, č. 326 (2010), s. 1067-1075 ISSN 0003-598X R&D Projects: GA AV ČR IAAX00020701; GA AV ČR IAA300130505 Institutional research plan: CEZ:AV0Z80020508; CEZ:AV0Z30130516 Keywords : Central Europe * early medieval * wood carving * fossil oak * alluvial setting Subject RIV: AC - Archeology, Anthropology, Ethnology Impact factor: 0.969, year: 2010 http://antiquity.ac.uk/ant/084/ant0841067.htm