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Sample records for medicine tip sheet

  1. Clean Firetube Boiler Waterside Heat Transfer Surfaces, Energy Tips: STEAM, Steam Tip Sheet #7 (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-04-01

    A steam energy tip sheet for the Advanced Manufacturing Office (AMO). The prevention of scale formation in firetube boilers can result in substantial energy savings. Scale deposits occur when calcium, magnesium, and silica, commonly found in most water supplies, react to form a continuous layer of material on the waterside of the boiler heat exchange tubes. Scale creates a problem because it typically possesses a thermal conductivity, an order of magnitude less than the corresponding value for bare steel. Even thin layers of scale serve as an effective insulator and retard heat transfer. The result is overheating of boiler tube metal, tube failures, and loss of energy efficiency. Fuel consumption may increase by up to 5% in firetube boilers because of scale. The boilers steam production may be reduced if the firing rate cannot be increased to compensate for the decrease in combustion efficiency. Energy losses as a function of scale thickness and composition are given. Any scale in a boiler is undesirable. The best way to deal with scale is not to let it form in the first place. Prevent scale formation by: (1) Pretreating of boiler makeup water (using water softeners, demineralizers, and reverse osmosis to remove scale-forming minerals); (2) Injecting chemicals into the boiler feedwater; and (3) Adopting proper boiler blowdown practices.

  2. Illinois Early Learning Project Tip Sheets: Social and Emotional Development.

    Science.gov (United States)

    2003

    The Illinois Early Learning Project (IEL) is funded by the Illinois State Board of Education to provide information resources on early learning and training related to implementing the Illinois Early Learning Standards for parents and for early childhood personnel in all settings. The IEL tip sheets offer suggestions to parents and early childhood…

  3. Assisted crack tip flipping under Mode I thin sheet tearing

    DEFF Research Database (Denmark)

    Felter, Christian Lotz; Nielsen, Kim Lau

    2017-01-01

    Crack tip flipping, where the fracture surface alternates from side to side in roughly 45° shear bands, seems to be an overlooked propagation mode in Mode I thin sheet tearing. In fact, observations of crack tip flipping is rarely found in the literature. Unlike the already established modes...... such as slanting, cup-cone (rooftop), or cup-cup (bathtub) the flipping crack never settles in a steady-state as the near tip stress/strain field continuously change when the flip successively initiates and develops shear-lips. A recent experimental investigation has revealed new insight by exploiting 3D X......-ray tomography scanning of a developing crack tip flip. But, it remains to be understood what makes the crack flip systematically, what sets the flipping frequency, and under which material conditions this mode occurs. The present study aims at investigating the idea that a slight out-of-plane action (Mode III...

  4. Cell sheet approach for tissue engineering and regenerative medicine.

    Science.gov (United States)

    Matsuura, Katsuhisa; Utoh, Rie; Nagase, Kenichi; Okano, Teruo

    2014-09-28

    After the biotech medicine era, regenerative medicine is expected to be an advanced medicine that is capable of curing patients with difficult-to-treat diseases and physically impaired function. Our original scaffold-free cell sheet-based tissue engineering technology enables transplanted cells to be engrafted for a long time, while fully maintaining their viability. This technology has already been applied to various diseases in the clinical setting, including the cornea, esophagus, heart, periodontal ligament, and cartilage using autologous cells. Transplanted cell sheets not only replace the injured tissue and compensate for impaired function, but also deliver growth factors and cytokines in a spatiotemporal manner over a prolonged period, which leads to promotion of tissue repair. Moreover, the integration of stem cell biology and cell sheet technology with sufficient vascularization opens possibilities for fabrication of human three-dimensional vascularized dense and intact tissue grafts for regenerative medicine to parenchymal organs. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Digit Tip Regeneration: Merging Regeneration Biology with Regenerative Medicine.

    Science.gov (United States)

    Dolan, Connor P; Dawson, Lindsay A; Muneoka, Ken

    2018-03-01

    Regeneration Biology is the study of organisms with endogenous regenerative abilities, whereas Regenerative Medicine focuses on engineering solutions for human injuries that do not regenerate. While the two fields are fundamentally different in their approach, there is an obvious interface involving mammalian regeneration models. The fingertip is the only part of the human limb that is regeneration-competent and the regenerating mouse digit tip has emerged as a model to study a clinically relevant regenerative response. In this article, we discuss how studies of digit tip regeneration have identified critical components of the regenerative response, and how an understanding of endogenous regeneration can lead to expanding the regenerative capabilities of nonregenerative amputation wounds. Such studies demonstrate that regeneration-incompetent wounds can respond to treatment with individual morphogenetic agents by initiating a multi-tissue response that culminates in structural regeneration. In addition, the healing process of nonregenerative wounds are found to cycle through nonresponsive, responsive and nonresponsive phases, and we call the responsive phase the Regeneration Window. We also find the responsiveness of mature healed amputation wounds can be reactivated by reinjury, thus nonregenerated wounds retain a potential for regeneration. We propose that regeneration-incompetent injuries possess dormant regenerative potential that can be activated by targeted treatment with specific morphogenetic agents. We believe that future Regenerative Medicine-based-therapies should be designed to promote, not replace, regenerative responses. Stem Cells Translational Medicine 2018;7:262-270. © 2018 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press.

  6. Development of a cell sheet transportation technique for regenerative medicine.

    Science.gov (United States)

    Oie, Yoshinori; Nozaki, Takayuki; Takayanagi, Hiroshi; Hara, Susumu; Hayashi, Ryuhei; Takeda, Shizu; Mori, Keisuke; Moriya, Noboru; Soma, Takeshi; Tsujikawa, Motokazu; Saito, Kazuo; Nishida, Kohji

    2014-05-01

    A transportation technique for cell sheets is necessary to standardize regenerative medicine. The aim of this article is to develop and evaluate a new transportation technique for cell sheets. We developed a transportation container with three basic functions: the maintenance of interior temperature, air pressure, and sterility. The interior temperature and air pressure were monitored by a recorder. Human oral mucosal epithelial cells obtained from two healthy volunteers were cultured on temperature-responsive culture dishes. The epithelial cell sheets were transported via an airplane between the Osaka University and Tohoku University using the developed cell transportation container. Histological and immunohistochemical analyses and flow cytometric analyses for cell viability and cell purity were performed for the cell sheets before and 12 h after transportation to assess the influence of transportation on the cell sheets. Sterility tests and screening for endotoxin and mycoplasma in the cell sheets were performed before and after transportation. During transportation via an airplane, the temperature inside the container was maintained above 32°C, and the changes in air pressure remained within 10 hPa. The cell sheets were well stratified and successfully harvested before and after transportation. The expression patterns of keratin 3/76, p63, and MUC16 were equivalent before and after transportation. However, the expression of ZO-1 in the cell sheet after transportation was slightly weaker than that before transportation. The cell viability was 72.0% before transportation and 77.3% after transportation. The epithelial purity was 94.6% before transportation and 87.9% after transportation. Sterility tests and screening for endotoxin and mycoplasma were negative for all cell sheets. The newly developed transportation technique for air travel is essential technology for regenerative medicine and promotes the standardization and spread of regenerative therapies.

  7. Experimental and Numerical Investigations of Applying Tip-bottomed Tool for Bending Advanced Ultra-high Strength Steel Sheet

    Science.gov (United States)

    Mitsomwang, Pusit; Borrisutthekul, Rattana; Klaiw-awoot, Ken; Pattalung, Aran

    2017-09-01

    This research was carried out aiming to investigate the application of a tip-bottomed tool for bending an advanced ultra-high strength steel sheet. The V-die bending experiment of a dual phase steel (DP980) sheet which had a thickness of 1.6 mm was executed using a conventional bending and a tip-bottomed punches. Experimental results revealed that the springback of the bent worksheet in the case of the tip-bottomed punch was less than that of the conventional punch case. To further discuss bending characteristics, a finite element (FE) model was developed and used to simulate the bending of the worksheet. From the FE analysis, it was found that the application of the tip-bottomed punch contributed the plastic deformation to occur at the bending region. Consequently, the springback of the worksheet reduced. In addition, the width of the punch tip was found to affect the deformation at the bending region and determined the springback of the bent worksheet. Moreover, the use of the tip-bottomed punch resulted in the apparent increase of the surface hardness of the bent worksheet, compared to the bending with the conventional punch.

  8. Talking about Complementary and Alternative Medicine with your Health Care Provider: A workbook and tips

    Science.gov (United States)

    A workbook to help patients and doctors talk about the use of complementary and alternative medicine(CAM) during and after cancer care. Worksheets, tips, and resources are provided for patients and doctors to help track CAM use.

  9. Talking about Complementary and Alternative Medicine with Health Care Providers: A Workbook and Tips

    Science.gov (United States)

    A workbook to help patients and doctors talk about the use of complementary and alternative medicine(CAM) during and after cancer care. Worksheets, tips, and resources are provided for patients and doctors to help track CAM use.

  10. Talking about Complementary and Alternative Medicine with Health Care Provider: A Workbook and Tips

    Science.gov (United States)

    A workbook to help patients and doctors talk about the use of complementary and alternative medicine(CAM) during and after cancer care. Worksheets, tips, and resources are provided for patients and doctors to help track CAM use.

  11. Quick Tips for Buying Medicines Over the Internet: A Consumer Safety Guide

    Science.gov (United States)

    ... Internet Quick Tips for Buying Medicines Over the Internet Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Make sure the site requires a prescription and has a pharmacist available for questions. Buy only from licensed pharmacies located in the United ...

  12. Multimode fibre: Light-sheet microscopy at the tip of a needle.

    Science.gov (United States)

    Plöschner, Martin; Kollárová, Věra; Dostál, Zbyněk; Nylk, Jonathan; Barton-Owen, Thomas; Ferrier, David E K; Chmelík, Radim; Dholakia, Kishan; Čižmár, Tomáš

    2015-12-14

    Light-sheet fluorescence microscopy has emerged as a powerful platform for 3-D volumetric imaging in the life sciences. Here, we introduce an important step towards its use deep inside biological tissue. Our new technique, based on digital holography, enables delivery of the light-sheet through a multimode optical fibre--an optical element with extremely small footprint, yet permitting complex control of light transport processes within. We show that this approach supports some of the most advanced methods in light-sheet microscopy: by taking advantage of the cylindrical symmetry of the fibre, we facilitate the wavefront engineering methods for generation of both Bessel and structured Bessel beam plane illumination. Finally, we assess the quality of imaging on a sample of fluorescent beads fixed in agarose gel and we conclude with a proof-of-principle imaging of a biological sample, namely the regenerating operculum prongs of Spirobranchus lamarcki.

  13. Twelve tips for teachers to encourage student engagement in academic medicine.

    Science.gov (United States)

    Lawson McLean, Aaron; Saunders, Christopher; Velu, Prasad Palani; Iredale, John; Hor, Kahyee; Russell, Clark D

    2013-07-01

    Recruitment of trainees into clinical academic medicine remains an area of concern across the globe, with clinical academics making up a dwindling proportion of the medical workforce. To date, few approaches have emphasised early medical student research involvement as a solution to the decline of the clinician-scientist. We identify 12 tips that all medical teachers can adopt to foster medical student participation in research and encourage student engagement with academic aspects of medicine throughout their time as an undergraduate. These recommendations are based on a comprehensive review of the international literature and our personal experience of research-focussed interventions and activities as medical students. Through these 12 tips, we provide a practical framework for enhancing medical student exposure to research at medical school. This has the potential to inspire and maintain student interest in the varied role of the clinical academic and could contribute to reversing the downward trend that has occurred in this field over recent times.

  14. Know Your School District: Tips for Parents. PACER Center ACTion Information Sheets. PHP-c112

    Science.gov (United States)

    PACER Center, 2006

    2006-01-01

    Becoming familiar with the school district will help parents become active and involved partners in their child's education. Research has demonstrated that family involvement in children's education can boost their academic success. Knowing about the following areas, which are discussed in this information sheet, can help parental involvement at…

  15. Taking Care of Your Diabetes Means Taking Care of Your Heart (Tip Sheet)

    Science.gov (United States)

    ... questions you have about your medicines. Cope with stress as best you can. Ask for help if ... eastern time, M-F Follow Us NIH… Turning Discovery Into Health ® Research & Funding Current Funding Opportunities Research ...

  16. [Research progress of cell sheet technology and its applications in tissue engineering and regenerative medicine].

    Science.gov (United States)

    Ma, Dongyang; Ren, Liling; Mao, Tianqiu

    2014-10-01

    Cell sheet engineering is an important technology to harvest the cultured cells in the form of confluent monolayers using a continuous culture method and a physical approach. Avoiding the use of enzymes, expended cells can be harvested together with endogenous extracellular matrix, cell-matrix contacts, and cell-cell contacts. With high efficiency of cell loading ability and without using exogenous scaffolds, cell sheet engineering has several advantages over traditional tissue engineering methods. In this article, we give an overview on cell sheet technology about its applications in the filed of tissue regeneration, including the construction of soft tissues (corneal, mucous membrane, myocardium, blood vessel, pancreas islet, liver, bladder and skin) and hard tissues (bone, cartilage and tooth root). This techonoly is promising to provide a novel strategy for the development of tissue engineering and regenerative medicine. And further works should be carried out on the operability of this technology and its feasibility to construct thick tissues.

  17. Medicine and ionizing rays: a help sheet in analysing risks in nuclear medicine

    International Nuclear Information System (INIS)

    Gauron, C.

    2006-01-01

    This document first proposes the various applicable legal and regulatory texts concerning radioprotection in the medical sector (European directives, institutions in charge of radioprotection, general arrangements, regulatory texts concerning worker protection against ionizing radiations, personnel specialized in medical radio-physics, electro-radiology operators, quality control of medical devices, and nuclear medicine and radiology). The second part proposes a synthesis of useful knowledge for radioprotection in the case of nuclear medicine when performing in vivo diagnosis, positron emission tomography or PET being excluded. Several aspects are considered: the concerned personnel, the course of treatment procedures, the hazards, the identification of the risk associated with ionizing radiation, the risk assessment and the determination of exposure levels, the strategy to control the risks (reduction of risks, technical measures concerning the installation or the personnel, teaching and information, prevention and medical monitoring), and risk control assessment. The next parts present the same kind of information but for positron emission tomography or PET with Fluorine 18, for therapeutic practice without hospitalization (activity of iodine 137 less than 740 MBq), for therapeutic practice in case of hospitalization (iodine 137 activity greater than 740 MBq), and when taking patients into care after treatment in a nuclear medicine (in this last case, legal and regulatory information focus on patients)

  18. Ten Tips for Engaging the Millennial Learner and Moving an Emergency Medicine Residency Curriculum into the 21st Century

    Science.gov (United States)

    Toohey, Shannon L.; Wray, Alisa; Wiechmann, Warren; Lin, Michelle; Boysen-Osborn, Megan

    2016-01-01

    Introduction Millennial learners are changing the face of residency education because they place emphasis on technology with new styles and means of learning. While research on the most effective way to teach the millennial learner is lacking, programs should consider incorporating educational theories and multimedia design principles to update the curriculum for these new learners. The purpose of the study is to discuss strategies for updating an emergency medicine (EM) residency program’s curriculum to accommodate the modern learner. Discussion These 10 tips provide detailed examples and approaches to incorporate technology and learning theories into an EM curriculum to potentially enhance learning and engagement by residents. Conclusion While it is unclear whether technologies actually promote or enhance learning, millennials use these technologies. Identifying best practice, grounded by theory and active learning principles, may help learners receive quality, high-yield education. Future studies will need to evaluate the efficacy of these techniques to fully delineate best practices. PMID:27330668

  19. Ten Tips for Engaging the Millennial Learner and Moving an Emergency Medicine Residency Curriculum into the 21st Century

    Directory of Open Access Journals (Sweden)

    Shannon L. Toohey

    2016-05-01

    Full Text Available Introduction: Millennial learners are changing the face of residency education because they place emphasis on technology with new styles and means of learning. While research on the most effective way to teach the millennial learner is lacking, programs should consider incorporating educational theories and multimedia design principles to update the curriculum for these new learners. The purpose of the study is to discuss strategies for updating an emergency medicine (EM residency program’s curriculum to accommodate the modern learner. Discussion: These 10 tips provide detailed examples and approaches to incorporate technology and learning theories into an EM curriculum to potentially enhance learning and engagement by residents. Conclusion: While it is unclear whether technologies actually promote or enhance learning, millennials use these technologies. Identifying best practice, grounded by theory and active learning principles, may help learners receive quality, high-yield education. Future studies will need to evaluate the efficacy of these techniques to fully delineate best practices.

  20. Ten Tips for Engaging the Millennial Learner and Moving an Emergency Medicine Residency Curriculum into the 21st Century.

    Science.gov (United States)

    Toohey, Shannon L; Wray, Alisa; Wiechmann, Warren; Lin, Michelle; Boysen-Osborn, Megan

    2016-05-01

    Millennial learners are changing the face of residency education because they place emphasis on technology with new styles and means of learning. While research on the most effective way to teach the millennial learner is lacking, programs should consider incorporating educational theories and multimedia design principles to update the curriculum for these new learners. The purpose of the study is to discuss strategies for updating an emergency medicine (EM) residency program's curriculum to accommodate the modern learner. These 10 tips provide detailed examples and approaches to incorporate technology and learning theories into an EM curriculum to potentially enhance learning and engagement by residents. While it is unclear whether technologies actually promote or enhance learning, millennials use these technologies. Identifying best practice, grounded by theory and active learning principles, may help learners receive quality, high-yield education. Future studies will need to evaluate the efficacy of these techniques to fully delineate best practices.

  1. Sports Information Online: Searching the SPORT Database and Tips for Finding Sports Medicine Information Online.

    Science.gov (United States)

    Janke, Richard V.; And Others

    1988-01-01

    The first article describes SPORT, a database providing international coverage of athletics and physical education, and compares it to other online services in terms of coverage, thesauri, possible search strategies, and actual usage. The second article reviews available online information on sports medicine. (CLB)

  2. Sports Injury Prevention Tip Sheet

    Science.gov (United States)

    ... than one person is jumping at a time. Sports-Related Emotional Stress The pressure to win can cause significant emotional stress for a child. Sadly, many coaches and parents consider winning the most important aspect of sports. Young athletes should be judged on effort, sportsmanship ...

  3. Remembering tips

    Science.gov (United States)

    Memory aids; Alzheimer disease - remembering tips; Early memory loss - remembering tips; Dementia - remembering tips ... active: Read a lot if you have trouble remembering words. Keep a dictionary close by. Take part ...

  4. Tips for TIPS

    NARCIS (Netherlands)

    Cuijpers, C.F.

    2015-01-01

    The transjugular intrahepatic portosystemic shunt (TIPS) procedure is one of the most technically challenging procedures in interventional radiology. During the procedure, interventional radiologists (IRs) insert very thin and long instruments through a little incision in the patient’s neck. They

  5. Tips for teachers of evidence-based medicine: making sense of decision analysis using a decision tree.

    Science.gov (United States)

    Lee, Anna; Joynt, Gavin M; Ho, Anthony M H; Keitz, Sheri; McGinn, Thomas; Wyer, Peter C

    2009-05-01

    Decision analysis is a tool that clinicians can use to choose an option that maximizes the overall net benefit to a patient. It is an explicit, quantitative, and systematic approach to decision making under conditions of uncertainty. In this article, we present two teaching tips aimed at helping clinical learners understand the use and relevance of decision analysis. The first tip demonstrates the structure of a decision tree. With this tree, a clinician may identify the optimal choice among complicated options by calculating probabilities of events and incorporating patient valuations of possible outcomes. The second tip demonstrates how to address uncertainty regarding the estimates used in a decision tree. We field tested the tips twice with interns and senior residents. Teacher preparatory time was approximately 90 minutes. The field test utilized a board and a calculator. Two handouts were prepared. Learners identified the importance of incorporating values into the decision-making process as well as the role of uncertainty. The educational objectives appeared to be reached. These teaching tips introduce clinical learners to decision analysis in a fashion aimed to illustrate principles of clinical reasoning and how patient values can be actively incorporated into complex decision making.

  6. Exposure of sheet-metal workers to asbestos during the construction and renovation of commercial buildings in New York City. A case study in social medicine.

    Science.gov (United States)

    Drucker, E; Nagin, D; Michaels, D; Lacher, M; Zoloth, S

    1987-01-01

    New York City sheet-metal workers have a history of significant exposure to asbestos. Prior to 1972 when the use of sprayed asbestos insulation was banned in New York City, sheet-metal workers involved in building construction were exposed as they worked adjacent to spraying operations. Subsequent to that date, exposure continued as they renovated these same buildings. In 1982 the Occupational Health Program of Montefiore Medical Center and the Albert Einstein College of Medicine initiated a multidimensional asbestos evaluation and intervention program for the sheet-metal industry and union in New York. The long-term goal of the program was to eliminate asbestos exposure through the safe, systematic removal of asbestos in New York City buildings, most likely a legislated solution. In the short term, we attempted to assess and reduce asbestos exposure in the sheet-metal trade by a series of steps consisting of: mortality and morbidity studies; a medical audit of clinical screening services provided to sheet-metal workers; a comprehensive health education program; development of safe work practices; evaluation of personal protective equipment; and investigation into and support of legislative and regulatory solutions to the problem of asbestos contamination of commercial buildings. This intervention can be seen as a case study in the practice of social medicine.

  7. Medicine and ionizing rays: a help sheet in analysing risks in radiotherapy and applicable texts

    International Nuclear Information System (INIS)

    Gauron, C.

    2007-01-01

    This document proposes a synthesis of useful knowledge for radioprotection in the case of external radiotherapy. In the first part, several aspects are considered: the concerned personnel, the course of treatment procedures, the hazards, the identification of the risk associated with ionizing radiation, the risk assessment and the exposure level determination, the strategy to control the risks (reduction of risks, technical measures concerning the installation or the personnel, teaching and information, prevention and medical monitoring), and risk control assessment. A second part indicates the various applicable legal and regulatory texts (European directives, law and decrees published by public authorities, and texts concerning the general principles in radioprotection, worker protection, specialists, medical devices, nuclear medicine and radiology)

  8. Tipping Point

    Medline Plus

    Full Text Available ... death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ... tv tip-overs. The force of a large television falling from tipping furniture can be staggering. A ...

  9. Tipping Point

    Medline Plus

    Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

  10. CFD analysis of cloud cavitation on three tip-modified propellers with systematically varied tip geometry

    DEFF Research Database (Denmark)

    Shin, K. W.; Andersen, Poul

    2015-01-01

    The blade tip loading is often reduced as an effort to restrain sheet and tip vortex cavitation in the design of marine propellers. This CFD analysis demonstrates that an excessive reduction of the tip loading can cause cloud cavitation responsible for much of noise and surface erosion. Detached...

  11. CFD analysis of cloud cavitation on three tip-modified propellers with systematically varied tip geometry

    Science.gov (United States)

    Shin, K. W.; Andersen, P.

    2015-12-01

    The blade tip loading is often reduced as an effort to restrain sheet and tip vortex cavitation in the design of marine propellers. This CFD analysis demonstrates that an excessive reduction of the tip loading can cause cloud cavitation responsible for much of noise and surface erosion. Detached eddy simulations (DES) are made for cavitating flows on three tip- modified propellers, of which one is a reference propeller having an experimental result from a cavitation tunnel test with a hull model, and the other two are modified from the reference propeller by altering the blade tip loading. DES results have been validated against the experiment in terms of sheet and cloud cavitation. In DES, non-uniform hull wake is modelled by using the inlet flow and momentum sources instead of including a hull model. A 4-bladed Kappel propeller with a smooth tip bending towards the suction side is used as the reference propeller. For the reference propeller, sheet cavitation extends over a whole chord length in the hull wake peak. As the blade gets out of the wake peak, the rear part of sheet cavity is detached in a form of cloud cavitation. For the reference propeller, the tip pitch reduction from the maximum is about 35%. When decreasing the tip pitch reduction to 10%, tip vortex cavitation is formed and cloud cavitation is significantly weakened. When increasing the tip pitch reduction to 60%, sheet cavitation slightly moves to inner radii and cloud cavitation grows larger.

  12. Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

    Science.gov (United States)

    Yamashita, Norio; Morita, Masahiko; Legant, Wesley R.; Chen, Bi-Chang; Betzig, Eric; Yokota, Hideo; Mimori-Kiyosue, Yuko

    2015-10-01

    Mitotic apparatus, which comprises hundreds of microtubules, plays an essential role in cell division, ensuring the correct segregation of chromosomes into each daughter cell. To gain insight into its regulatory mechanisms, it is essential to detect and analyze the behavior of individual microtubule filaments. However, the discrimination of discrete microtubule filaments within the mitotic apparatus is beyond the capabilities of conventional light microscopic technologies. Recently, we detected three-dimensional (3-D) microtubule growth dynamics within the cellular cytoplasmic space using lattice light-sheet microscopy in conjunction with microtubule growth marker protein end-binding 1, a microtubule plus-end-tracking protein, which was fused to green fluorescent protein (EB1-GFP). This technique enables high-resolution 3-D imaging at subsecond intervals. We adapted mathematical computing and geometric representation techniques to analyze spatial variations in microtubule growth dynamics within the mitotic spindle apparatus. Our analytical approach enabled the different dynamic properties of individual microtubules to be determined, including the direction and speed of their growth, and their growth duration within a 3-D spatial map. Our analysis framework provides an important step toward a more comprehensive understanding of the mechanisms driving cellular machinery at the whole-cell level.

  13. Ten Tips for Engaging the Millennial Learner and Moving an Emergency Medicine Residency Curriculum into the 21st Century

    OpenAIRE

    Toohey, Shannon L.; Wray, Alisa; Wiechmann, Warren; Lin, Michelle; Boysen-Osborn, Megan

    2016-01-01

    Introduction: Millennial learners are changing the face of residency education because they place emphasis on technology with new styles and means of learning. While research on the most effective way to teach the millennial learner is lacking, programs should consider incorporating educational theories and multimedia design principles to update the curriculum for these new learners. The purpose of the study is to discuss strategies for updating an emergency medicine (EM) residency program’s ...

  14. Tipping Point

    Medline Plus

    Full Text Available ... OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point ... 24 hours a day. For young children whose home is a playground, it’s the best way to ...

  15. CPAP Tips

    Medline Plus

    Full Text Available ... a continuous positive airway pressure (CPAP) device when sleeping? Here are some tips from the U.S. Food ... 395,755 views 9:28 3 Tips for Sleeping With a CPAP - Duration: 2:02. WebMD 66, ...

  16. Rapid in vitro propagation system through shoot tip cultures of Vitex trifolia L.-an important multipurpose plant of the Pacific traditional Medicine.

    Science.gov (United States)

    Ahmed, Rafique; Anis, Mohammad

    2014-07-01

    A rapid and efficient plant propagation system through shoot tip explants was established in Vitex trifolia L., a medicinally important plant belonging to the family Verbenaceae. Multiple shoots were induced directly on Murashige and Skoog (MS) medium consisting of different cytokinins, 6-benzyladenine (BA), kinetin (Kin) and 2-isopentenyl adenine (2-iP), BA at an optimal concentration of 5.0 μM was most effective in inducing multiple shoots where 90 % explants responded with an average shoot number (4.4±0.1) and shoot length (2.0±0.1 cm) after 6 weeks of culture. Inclusion of NAA in the culture medium along with the optimum concentration of BA promoted a higher rate of shoot multiplication and length of the shoot, where 19.2±0.3 well-grown healthy shoots with an average shoot length of 4.4±0.1 cm were obtained on completion of 12 weeks culture period. Ex vitro rooting was achieved best directly in soilrite when basal portion of the shoots were treated with 500 μM indole-3-butyric acid for 15 min which was the most effective in inducing roots, as 95 % of the microshoots produced roots. Plantlets went through a hardening phase in a controlled plant growth chamber, prior to ex-vitro transfer. Micropropagated plants grew well, attained maturity and flowered with 92 % survival rate. The results of this study provide the first report on in vitro plant regeneration of Vitex trifolia L. using shoot tip explants.

  17. Complementary and alternative medicine (CAM) use in an Italian cohort of pediatric headache patients: the tip of the iceberg.

    Science.gov (United States)

    Dalla Libera, D; Colombo, B; Pavan, G; Comi, G

    2014-05-01

    The use of complementary alternative medicine (CAM) in paediatric populations is considerably increased, especially for pain and chronic conditions, as demonstrated by epidemiological surveys both in Europe and in the USA. In our study, CAM was used in 76 % patients of a cohort of 124 children affected by headache (age 4-16 years; 67 % female; 70 % migraine without aura, 12 % migraine with aura, 18 % tensive headache according to IHS criteria) consecutively recruited at a Pediatric Headache University Center. CAM was used as preventive treatment in 80 % cases. The main reasons for seeking CAM were: the wish of avoiding chronic use of drugs with their related side effects, the desire of an integrated approach, the reported inefficacy of conventional medicine, and a more suitable children disposition to CAM than to pharmacological compound. Female gender, younger age, migraine without aura, parents' higher educational status, maternal use of CAM and other associated chronic conditions, correlated with CAM use (p CAM also to treat other diseases (i.e. allergies, colitis, asthma, insomnia, muscle-scheletric disorders and dysmenorrhoea). The most assumed CAM were: herbal remedies (64 %) such as Valeriana, Ginkgo biloba, Boswellia serrata, Vitex agnus-castus, passion flower, Linden tree; vitamins/minerals supplements (40 %) with magnesium, 5-Hydroxytryptophan, vitamin B6 or B12, Multivitamin compounds; Homeopathy (47 %) with Silicea, Ignatia Amara, Pulsatilla, Aconitum, Nux Vomica, Calcarea phosphorica; physical treatment (45 %) such as Ayurvedic massage, shiatsu, osteopathy; yoga (33 %); acupuncture (11 %). CAM-often integrated with conventional care-was auto-prescribed in 30 % of the cases, suggested by non-physician in 22 %, by the General Practitioner in 24 % and by paediatrician in 24 %. Both general practitioners and neurologists were mostly unaware of their patients' CAM use. In conclusion, neurologists should inquire for CAM use and be prepared to learn about CAM

  18. Tipping Point

    Medline Plus

    Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... see news reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The ...

  19. CPAP Tips

    Medline Plus

    Full Text Available ... make your opinion count. Sign in Loading... Loading... Transcript The interactive transcript could not be loaded. Loading... ... Dan Uses CPAP - Duration: 4:17. Harvard Medical School 7,950 views 4:17 Tips for building ...

  20. CPAP Tips

    Science.gov (United States)

    ... make your opinion count. Sign in Loading... Loading... Transcript The interactive transcript could not be loaded. Loading... ... Dan Uses CPAP - Duration: 4:17. Harvard Medical School 7,950 views 4:17 Tips for building ...

  1. Tipping Point

    Medline Plus

    Full Text Available ... fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash format. Almost ... accidents involving young children and furniture, appliance and tv tip-overs. The force of a large television ...

  2. Tipping Point

    Medline Plus

    Full Text Available ... impact can kill a child or cause severe injuries. About 16,000 (mostly young children) were treated in emergency rooms for tip-over related injuries in 2006, that’s about four times more injuries ...

  3. Tipping Point

    Medline Plus

    Full Text Available ... appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch ... reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The force of ...

  4. Tipping Point

    Medline Plus

    Full Text Available ... third story of a building. That kind of impact can kill a child or cause severe injuries. ... to prevent a tip-over tragedy. Share Post Facebook Twitter Google Plus Reddit Connect with Me:  Visit ...

  5. Tipping Point

    Medline Plus

    Full Text Available ... 24 hours a day. For young children whose home is a playground, it’s the best way to prevent a tip-over tragedy. Share Post Facebook Twitter ... Security, and Legal Notice | Accessibility Policy | Open Government @ CPSC | ...

  6. CPAP Tips

    Medline Plus

    Full Text Available ... sleeping? Here are some tips from the U.S. Food and Drug Administration (FDA) on how to safely ... Copyright Creators Advertise Developers +YouTube Terms Privacy Policy & Safety Send feedback Test new features Loading... Working... Sign ...

  7. Tip enhancement

    CERN Document Server

    Kawata, Satoshi

    2007-01-01

    This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field.·Near-field Raman scattering·Tip-enhanced Raman spectroscopy·Surface-enhanced Raman spectroscopy·Nano-photonics·Nanoanalysis of Physical, chemical and biological materials beyond the diffraction limits·Single molecule detection

  8. Shoot-tip cryopreservation by droplet vitrification of Byrsonima intermedia A. Juss.: a woody tropical and medicinal plant species from Brazilian cerrado.

    Science.gov (United States)

    Silva, L C; Paiva, R; Swennen, R; Andre, E; Panis, B

    2013-01-01

    Cryopreservation of plant species is poorly investigated in Brazil. The aim of this study was to cryopreserve Byrsonima intermedia shoot apical meristems through droplet vitrification. A culture medium for shoot-tips growth was established using the Woody Plant Medium supplemented with 2.22 uM 6-benzylaminopurine. Excised shoot-tips were subjected to pre-culture and/or post-culture treatments on Murashige and Skoog medium with 0.3 M sucrose for 24 h prior dehydration on PVS2 at 0°C for 15, 30 or 45 minutes prior to plunging in liquid nitrogen. The effect of 15 days of shoot pre-growth on a high osmotic medium (0.3 M sucrose or 0.21 M sorbitol + 0.09 M sucrose) prior to meristem excision and cryopreservation was also investigated. Pre-culturing shoot-tips on 0.3 M sucrose for 24 h prior to cryopreservation increased the regrowth level after thawing to 90%. Shoot-tips excised from shoots pre-grown on MS + 0.21 M sorbitol + 0.09 M sucrose for 15 days presented a satisfactory regrowth level (67%).

  9. Prom Health and Safety Tips

    Science.gov (United States)

    ... Autumn Tips Camping Tips Family Reunions Gardening Tips Halloween Tips Healthy Halloween Prom Tips Spring Break Valentine Tips Winter Holiday ... Breast Cancer Assess Your Relationships Be Safe on Halloween Be Smoke-Free Check Alarm Batteries Know Your ...

  10. Tips for Daily Living

    Science.gov (United States)

    ... Tips and Gadgets for Daily Activities Dressing Tips Shopping Tips Modifying the Bathroom Driving After Stroke Medication ... and resources. Find a group in your area . Online Support If there is not a support group ...

  11. Cryopreservation of in vitro-grown shoot tips of Chinese medicinal plant Atractylodes macrocephala Koidz. using a droplet-vitrification method

    Science.gov (United States)

    BACKGROUND: Atractylodes macrocephala Koidz. is an important medicinal species from China and has been used for thousands of years because of pharmacological antioxidant, hepatoprotective, anti-inflammatory, anti-allergic, antithrombotic, antiviral, and anticarcinogenic activities. OBJECTIVE: The ai...

  12. Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope for in-vivo imaging in medicine and biomedical research.

    Science.gov (United States)

    Matz, Gregor; Messerschmidt, Bernhard; Göbel, Werner; Filser, Severin; Betz, Christian S; Kirsch, Matthias; Uckermann, Ortrud; Kunze, Marcel; Flämig, Sven; Ehrhardt, André; Irion, Klaus-Martin; Haack, Mareike; Dorostkar, Mario M; Herms, Jochen; Gross, Herbert

    2017-07-01

    We demonstrate a 60 mg light video-endomicroscope with a cylindrical shape of the rigid tip of only 1.6 mm diameter and 6.7 mm length. A novel implementation method of the illumination unit in the endomicroscope is presented. It allows for the illumination of the biological sample with fiber-coupled LED light at 455 nm and the imaging of the red-shifted fluorescence light above 500 nm in epi-direction. A large numerical aperture of 0.7 leads to a sub-cellular resolution and yields to high-contrast images within a field of view of 160 μ m. A miniaturized chip-on-the-tip CMOS image sensor with more than 150,000 pixels captures the multicolor images at 30 fps. Considering size, plug-and-play capability, optical performance, flexibility and weight, we hence present a probe which sets a new benchmark in the field of epifluorescence endomicroscopes. Several ex-vivo and in-vivo experiments in rodents and humans suggest future application in biomedical fields, especially in the neuroscience community, as well as in medical applications targeting optical biopsies or the detection of cellular anomalies.

  13. Mind-Body Medicine Practices in Complementary and Alternative Medicine

    Science.gov (United States)

    ... Fact Sheets Home > Mind-Body Medicine Practices in Complementary and Alternative Medicine Small Text Medium Text Large Text Mind-Body Medicine Practices in Complementary and Alternative Medicine YESTERDAY The concept that the mind is important ...

  14. Hazard Communication Standard for Chemical Labels and Safety Data Sheets In GHS Format

    Science.gov (United States)

    This fact sheet provides an overview of the required contents of Safety Data Sheets (SDSs) and chemical hazard labels, and includes tips on how these materials can be used to better protect health and the environment.

  15. Healthy Vision Tips

    Science.gov (United States)

    ... for Kids >> Healthy Vision Tips Listen All About Vision About the Eye Ask a Scientist Video Series ... Links to More Information Optical Illusions Printables Healthy Vision Tips Healthy vision starts with you! Use these ...

  16. Digestive Health Tips

    Science.gov (United States)

    ... Home / Digestive Health Topic / Digestive Health Tips Digestive Health Tips Basics 10 Tips on Belching, Bloating, and Flatulence Belching is caused by swallowed air from: Eating or drinking too fast Poorly fitting dentures; not chewing food completely Carbonated beverages Chewing gum or sucking on ...

  17. Tip studies using CFD and comparison with tip loss models

    DEFF Research Database (Denmark)

    Hansen, Martin Otto Laver; Johansen, J.

    2004-01-01

    The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD......The flow past a rotating LM8.2 blade equipped with two different tips are computed using CFD. The different tip flows are analysed and a comparison with two different tip loss models is made. Keywords: tip flow, aerodynamics, CFD...

  18. The TIPS Liquidity Premium

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller; Christensen, Jens H.E.; Simon Riddell, Simon

    We introduce an arbitrage-free term structure model of nominal and real yields that accounts for liquidity risk in Treasury inflation-protected securities (TIPS). The novel feature of our model is to identify liquidity risk from individual TIPS prices by accounting for the tendency that TIPS, like...... most fixed-income securities, go into buy-and-hold investors' portfolios as time passes. We find a sizable and countercyclical TIPS liquidity premium, which greatly helps our model in matching TIPS prices. Accounting for liquidity risk also improves the model's ability to forecast inflation and match...

  19. Arctic climate tipping points.

    Science.gov (United States)

    Lenton, Timothy M

    2012-02-01

    There is widespread concern that anthropogenic global warming will trigger Arctic climate tipping points. The Arctic has a long history of natural, abrupt climate changes, which together with current observations and model projections, can help us to identify which parts of the Arctic climate system might pass future tipping points. Here the climate tipping points are defined, noting that not all of them involve bifurcations leading to irreversible change. Past abrupt climate changes in the Arctic are briefly reviewed. Then, the current behaviour of a range of Arctic systems is summarised. Looking ahead, a range of potential tipping phenomena are described. This leads to a revised and expanded list of potential Arctic climate tipping elements, whose likelihood is assessed, in terms of how much warming will be required to tip them. Finally, the available responses are considered, especially the prospects for avoiding Arctic climate tipping points.

  20. Tipping elements in the Arctic marine ecosystem.

    Science.gov (United States)

    Duarte, Carlos M; Agustí, Susana; Wassmann, Paul; Arrieta, Jesús M; Alcaraz, Miquel; Coello, Alexandra; Marbà, Núria; Hendriks, Iris E; Holding, Johnna; García-Zarandona, Iñigo; Kritzberg, Emma; Vaqué, Dolors

    2012-02-01

    The Arctic marine ecosystem contains multiple elements that present alternative states. The most obvious of which is an Arctic Ocean largely covered by an ice sheet in summer versus one largely devoid of such cover. Ecosystems under pressure typically shift between such alternative states in an abrupt, rather than smooth manner, with the level of forcing required for shifting this status termed threshold or tipping point. Loss of Arctic ice due to anthropogenic climate change is accelerating, with the extent of Arctic sea ice displaying increased variance at present, a leading indicator of the proximity of a possible tipping point. Reduced ice extent is expected, in turn, to trigger a number of additional tipping elements, physical, chemical, and biological, in motion, with potentially large impacts on the Arctic marine ecosystem.

  1. HIV Medicines and Side Effects

    Science.gov (United States)

    ... Apps skip to content Side Effects of HIV Medicines Home Understanding HIV/AIDS Fact Sheets HIV Medicines ... p.m. ET) Send us an email HIV Medicines and Side Effects Last Reviewed: October 9, 2017 ...

  2. Orientation and Morphology Effects in Rapid Silicon Sheet Solidification

    Science.gov (United States)

    Ciszek, T. F.

    1984-01-01

    Radial growth anisotropies and equilibrium forms of point nucleated, dislocation free silicon sheets spreading horizontally on the free surface of a silicon melt were measured for (100), (110), (111), and (112) sheet planes. The growth process was recorded. Qualitative Wulff surface free energy polar plots were deduced from the equilibrium shapes for each sheet plane. Predicted geometries for the tip shape of unidirectional, dislocation free, horizontally grown sheets growing in various directions within the planes were analyzed. Polycrystalline sheets and dendrite propagation were analyzed. For dendrites, growth rates on the order of 2.5 m/min and growth rate anisotropies of 25 are measured.

  3. Efficient regeneration of plants from shoot tip explants of ...

    African Journals Online (AJOL)

    Dendrobium densiflorum Lindl. is one of the horticulturally important orchids of Nepal due to its beautiful yellowish flower and medicinal properties. The present study was carried out for plant regeneration from shoot tip explants of D. densiflorum by tissue culture technique. The shoot tip explants of this species, obtained ...

  4. Tips in Reading Instruction.

    Science.gov (United States)

    Ediger, Marlow

    Some tips can assist teachers in guiding each pupil to achieve more optimally, with respect to the ability to read well and reading comprehension. Among these 10 specific tips are: (1) teach individualized phonics in context; (2) assist the student to read in proper thought units by covering up words in sentences for clarification; (3) assist…

  5. ADHD: Tips to Try

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español ADHD: Tips to Try KidsHealth / For Teens / ADHD: Tips to Try Print en español TDAH: Consejos que puedes probar ADHD , short for attention deficit hyperactivity disorder , is a ...

  6. Total Telephone Tips.

    Science.gov (United States)

    Corder, Lloyd E.; And Others

    This manual of telephone behavior tips for business and sales professionals offers ways to handle the disgruntled caller and makes suggestions on topics relevant to the telephone. The manual is divided into the following sections and subsections: (1) Common Courtesy (staff tips, answering the telephone, screening calls, transferring calls, taking…

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... the liver). Portal hypertension can also occur in children, although children are much less likely to require a TIPS. ... intentionally to solve the problem. Although extremely rare, children may also require a TIPS procedure. TIPS in ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... vs. risks? What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A ... likely to require a TIPS. top of page What are some common uses of the procedure? A ...

  9. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... TIPS is a minimally invasive procedure that typically has a shorter recovery time than surgery. Your TIPS ...

  10. Tips for Kids: Lower Your Risk for Type 2 Diabetes

    Science.gov (United States)

    US Department of Health and Human Services, 2005

    2005-01-01

    Today, more kids have type 2 diabetes than ever before. This colorful, easy-to-read tip sheet encourages young people to take steps to lower their risk for type 2 diabetes. A list of warning signs and a healthy eating guide is offered, along with a list of websites to learn more. [This brochure was prepared by the Department of Health and Human…

  11. First Aid Tips

    Science.gov (United States)

    ... Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home » NEI for Kids » First Aid Tips Listen All About Vision About the Eye ...

  12. Tips for Daily Life

    Science.gov (United States)

    ... chapter Join our online community Tips for Daily Life Coping skills will help you handle day-to- ... challenges, maximize your independence and live a meaningful life with your diagnosis. Accepting changes Creating a coping ...

  13. Toilet training tips

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000944.htm Toilet training tips To use the sharing features on ... and 'pee'. Teaching Your Child to Use the Toilet Once your child is comfortable sitting on the ...

  14. Crack Tip Flipping Under Mode I/III Tearing

    DEFF Research Database (Denmark)

    Felter, Christian Lotz; Specht Jensen, Lasse; Nielsen, Kim Lau

    Crack tip flipping, where the fracture surface alternates from side to side in 45° shear bands, seems to be an overlooked propagation mode in Mode I sheet tearing often disregarded as  “transitional” or tied to randomness in the material. In fact, such observations rarely make it to the literature....... However, crack tip flipping is a true propagation mode, but unlike those already established: i) it never settles in a steady-state as the near tip stress/strain field continuously change, and ii) the mechanism governing failure evolves behind the leading crack tip. Recent research has revealed new...... insight into this intriguing behavior of a crack propagating by the void nucleation and growth mechanism, and the work presented compiles both published and unpublished experimental and numerical findings. E.g. in a recent attempt to gain control of the flipping crack a slight Mode III was imposed...

  15. CSC Tip Sheets: Community-Based Social Marketing

    Science.gov (United States)

    Use community-based social marketing (CBSM) to facilitate direct neighbor-to-neighbor communication and influence to promote behavior change. In-person communications are often complemented by electronic social media tools.

  16. Magnet pole tips

    Science.gov (United States)

    Thorn, Craig E.; Chasman, Chellis; Baltz, Anthony J.

    1984-04-24

    An improved magnet which more easily provides a radially increasing magnetic field, as well as reduced fringe field and requires less power for a given field intensity. The subject invention comprises a pair of spaced, opposed magnetic poles which further comprise a pair of pole roots, each having a pole tip attached to its center. The pole tips define the gap between the magnetic poles and at least a portion of each pole tip is separated from its associated pole root. The separation begins at a predetermined distance from the center of the pole root and increases with increasing radial distance while being constant with azimuth within that portion. Magnets in accordance with the subject invention have been found to be particularly advantageous for use in large isochronous cyclotrons.

  17. GASN sheets

    International Nuclear Information System (INIS)

    2013-12-01

    This document gathers around 50 detailed sheets which describe and present various aspects, data and information related to the nuclear sector or, more generally to energy. The following items are addressed: natural and artificial radioactive environment, evolution of energy needs in the world, radioactive wastes, which energy for France tomorrow, the consequences in France of the Chernobyl accident, ammunitions containing depleted uranium, processing and recycling of used nuclear fuel, transport of radioactive materials, seismic risk for the basic nuclear installations, radon, the precautionary principle, the issue of low doses, the EPR, the greenhouse effect, the Oklo nuclear reactors, ITER on the way towards fusion reactors, simulation and nuclear deterrence, crisis management in the nuclear field, does nuclear research put a break on the development of renewable energies by monopolizing funding, nuclear safety and security, the plutonium, generation IV reactors, comparison of different modes of electricity production, medical exposure to ionizing radiations, the control of nuclear activities, food preservation by ionization, photovoltaic solar collectors, the Polonium 210, the dismantling of nuclear installations, wind energy, desalination and nuclear reactors, from non-communication to transparency about nuclear safety, the Jules Horowitz reactor, CO 2 capture and storage, hydrogen, solar energy, the radium, the subcontractors of maintenance of the nuclear fleet, biomass, internal radio-contamination, epidemiological studies, submarine nuclear propulsion, sea energy, the Three Mile Island accident, the Chernobyl accident, the Fukushima accident, the nuclear after Fukushima

  18. Fact Sheet for Preventing and Detecting PCB Contamination in Used Oil

    Science.gov (United States)

    This fact sheet provides tips on how to reduce the mismanagement of used oil contaminated with PCBs, a recurring issue faced by EPA and states, commercial and municipal used oil collection centers and recyclers.

  19. Tips from the Classroom.

    Science.gov (United States)

    Wilhelm, Kim Hughes; Leverett, Thomas; Barrett, Rob J.; Chur-Hansen, Anna; Dantas-Whitney, Maria; Zapata, Gabriela; Garcia, Juan Felix

    1998-01-01

    Five articles present tips for rallying English-as-a-Second-Language students to the enterprise of creating context, tools, and language itself. The articles focus on using original dramas created by students, teaching nonnative English-speaking medical students to comprehend their patients' colloquial language, conducting research with native…

  20. Air Travel Health Tips

    Science.gov (United States)

    ... Conditions Prevention and Wellness Staying Healthy Healthy Living Travel Occupational Health First Aid and Injury Prevention Crisis ... MoreDepression in Children and TeensRead MoreBMI Calculator International Travel: Tips for Staying HealthyTexting and DrivingTravel Needs for ...

  1. 10 Data Visualization Tips

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    communicated through the use of design choices. (as indicated in tip 8). 8. Use colour, size, and position to help the reader see what is important. Colour adds emphasis, highlights particular data points, and draws connections between graphs. The hue, value, and intensity of the colour are significant and may have cultural ...

  2. Sports Dehydration Safety Tips

    Science.gov (United States)

    Sports Dehydration Safety Tips Everything you need to know to keep your kids safe from dehydration when playing sports. To keep kids in top ... to stay hydrated by drinking plenty of fluids. Dehydration occurs when a body loses more water than ...

  3. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... TIPS. top of page What are some common uses of the procedure? A TIPS is used to ... the scanner by a cord. Some exams may use different transducers (with different capabilities) during a single ...

  4. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... or bypass, without the risks that accompany open surgery. TIPS is a minimally invasive procedure that typically has a shorter recovery time than surgery. Your TIPS should have less of an effect ...

  5. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... then placed in this tunnel to keep the pathway open. Patients who typically need a TIPS have ... and stomach. A TIPS procedure involves creating a pathway through the liver that connects the portal vein ( ...

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... and/or hydrothorax (in the chest). Budd-Chiari syndrome , a blockage in one or more veins that ... intentionally to solve the problem. Although extremely rare, children may also require a TIPS procedure. TIPS in ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... heart while avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and esophagus in ... TIPS reroutes blood flow in the liver and reduces abnormally high blood pressure in the veins of ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... What are the limitations of TIPS? What is a Transjugular Intrahepatic Portosystemic Shunt (TIPS)? A transjugular intrahepatic ... taking our brief survey: Survey Do you have a personal story about radiology? Share your patient story ...

  9. Using Cascading Style Sheets to Design a Fly-Out Menu with Microsoft Visual Studio

    Science.gov (United States)

    Liu, Chang; Downing, Charles

    2010-01-01

    The menu has become an integrated component within nearly all professionally designed websites. This teaching tip presents a no-code way to design either a vertical or a horizontal fly-out menu by using Cascading Style Sheets (CSS) within Microsoft Visual Studio 2008. The approach described in this tip helps students fully understand how to…

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... liver disease are at greater risk for worsening liver failure after TIPS. If your liver failure is severe, a TIPS may not be the best use and a different procedure may be needed to control your symptoms. ... ordinarily filtered out by the liver. The TIPS may cause too much of these ...

  11. Tip-modified Propellers

    DEFF Research Database (Denmark)

    Andersen, Poul

    1999-01-01

    The paper deals with tip-modified propellers and the methods which, over a period of two decades, have been applied to develop such propellers. The development is driven by the urge to increase the efficiency of propellers and can be seen as analogous to fitting end plates and winglets to aircraft...... propeller, have efficiency increases of a reasonable magnitude in both open-water and behind-ship conditions....

  12. Smoking - Medicines to Help You Quit

    Science.gov (United States)

    ... For Consumers Consumer Information by Audience For Women Smoking - Medicines To Help You Quit Share Tweet Linkedin ... associated with the use of the medicine. Quit Smoking Tips Quit Smoking… for yourself and for those ...

  13. Cholera Fact Sheet

    Science.gov (United States)

    ... sheets Fact files Questions & answers Features Multimedia Contacts Cholera Fact sheet Updated December 2017 Key facts Cholera ... behaviour and to the control of cholera. Oral cholera vaccines Currently there are three WHO pre-qualified ...

  14. Tipping point leadership.

    Science.gov (United States)

    Kim, W Chan; Mauborgne, Renée

    2003-04-01

    When William Bratton was appointed police commissioner of New York City in 1994, turf wars over jurisdiction and funding were rife and crime was out of control. Yet in less than two years, and without an increase in his budget, Bratton turned New York into the safest large city in the nation. And the NYPD was only the latest of five law-enforcement agencies Bratton had turned around. In each case, he succeeded in record time despite limited resources, a demotivated staff, opposition from powerful vested interests, and an organization wedded to the status quo. Bratton's turnarounds demonstrate what the authors call tipping point leadership. The theory of tipping points hinges on the insight that in any organization, fundamental changes can occur quickly when the beliefs and energies of a critical mass of people create an epidemic movement toward an idea. Bratton begins by overcoming the cognitive hurdles that block organizations from recognizing the need for change. He does this by putting managers face-to-face with operational problems. Next, he manages around limitations on funds, staff, or equipment by concentrating resources on the areas that are most in need of change and that have the biggest payoffs. He meanwhile solves the motivation problem by singling out key influencers--people with disproportionate power due to their connections or persuasive abilities. Finally, he closes off resistance from powerful opponents. Not every CEO has the personality to be a Bill Bratton, but his successes are due to much more than his personality. He relies on a remarkably consistent method that any manager looking to turn around an organization can use to overcome the forces of inertia and reach the tipping point.

  15. AERODYNAMICS OF WING TIP SAILS

    Directory of Open Access Journals (Sweden)

    MUSHTAK AL-ATABI

    2006-06-01

    Full Text Available Observers have always been fascinated by soaring birds. An interesting feature of these birds is the existence of few feathers extending from the tip of the wing. In this paper, small lifting surfaces were fitted to the tip of a NACA0012 wing in a fashion similar to that of wing tip feathers. Experimental measurements of induced drag, longitudinal static stability and trailing vortex structure were obtained.The tests showed that adding wing tip surfaces (sails decreased the induced drag factor and increased the longitudinal static stability. Results identified two discrete appositely rotated tip vortices and showed the ability of wing tip surfaces to break them down and to diffuse them.

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... liver disease are at greater risk for worsening liver failure after TIPS. If your liver failure is severe, a TIPS may not be the ... children are more likely to be performed before liver transplant in those with ascites or variceal ... 08, 2017 Send us your feedback Did you find the ...

  17. Tipping the scales.

    Science.gov (United States)

    1998-12-01

    In the US, the October 1998 murder of a physician who performed abortions was an outward manifestation of the insidious battle against legal abortion being waged by radical Christian social conservatives seeking to transform the US democracy into a theocracy. This movement has been documented in a publication entitled, "Tipping the Scales: The Christian Right's Legal Crusade Against Choice" produced as a result of a 4-year investigation conducted by The Center for Reproductive Law and Policy. This publication describes how these fundamentalists have used sophisticated legal, lobbying, and communication strategies to further their goals of challenging the separation of church and state, opposing family planning and sexuality education that is not based solely on abstinence, promoting school prayer, and restricting homosexual rights. The movement has resulted in the introduction of more than 300 anti-abortion bills in states, 50 of which have passed in 23 states. Most Christian fundamentalist groups provide free legal representation to abortion clinic terrorists, and some groups solicit women to bring specious malpractice claims against providers. Sophisticated legal tactics are used by these groups to remove the taint of extremism and mask the danger posed to US constitutional principles being posed by "a well-financed and zealous brand of radical lawyers and their supporters."

  18. Torsional Phacoemulsification and Tip Selection

    Directory of Open Access Journals (Sweden)

    Fırat Helvacıoğlu

    2014-10-01

    Full Text Available One of the recent advances in cataract surgery is torsional phacoemulsification. It was developed to increase the efficacy of ultrasonic emulsification. In torsional phacoemulsification, the torsional movement of the tip is translated to side-to-side cutting action with the aid of bent phaco tips. Lens material is cut in both directions, rather than only during a forward stroke. The efficiency of this technique is further enhanced by an improvement in followability provided by the inherent non-repulsive nature of the side-to-side motion. Tip selection is very important for the efficiency of torsional phacoemulsification. Theoretically, there are 2 ways to enhance the cutting efficiency of the tip. First is the stroke length; the 22-degree bent 30-degree Kelman mini-flared tip cuts longer than the 12-degree bent 30-degree mini-flared Kelman tip. Second is the angulation or bevel; the higher the degree (45 degrees, the better cutting efficiency. Retrospective analyses of the previously published clinical studies clearly demonstrated that the efficacy of the torsional phacoemulsification has positive correlation with both the aperture angles and neck angles of the tips. (Turk J Ophthalmol 2014; 44: 392-5

  19. Numerical Analysis of Tip Cavitation on Marine Propeller with Wake Alignment Using a Simple Surface Panel Method “SQCM”

    Science.gov (United States)

    Kanemaru, T.; Ando, J.

    2015-12-01

    This paper presents the calculation method of tip cavitation with wake alignment. Tip cavitation consists of tip vortex cavitation and tip super cavitation which means the undeveloped and local super cavitation around blade tip. The feature of this study is that the method applies the wake alignment model in order to express the realistic phenomena of tip cavitation and predict the pressure fluctuation more accurately. In the present method, the wake sheet is deformed according to the induced velocity vector on the vortex lines. The singularity of the potential vortex can be removed by using the Rankine Vortex model. This paper shows the calculated results regarding cavitation pattern, pressure fluctuation etc. comparing with published experimental data and calculated results without wake alignment.

  20. Intermetallic Cu3Sn Phase Layer on Electrode’s Tip of Galvanized Resistance Spot Welding

    Directory of Open Access Journals (Sweden)

    Muhammad Anis

    2010-10-01

    Full Text Available A resistance spot welding method is commonly used in automotive industries application. In a resistance spot welding method, the copper electrode has a significant role as an electric current carrier for joining thin metal sheet. This research was focused on studying the effect of tin layer at the electrode tip for joining galvanized steel sheet. The main variable of this research is in the thickness of the intermetallic Cu3Sn layer. The result showed that the introduction of tin layer less than 1 μm in thickness on the electrode tip gives a comparable shear strength and nugget diameter distribution with the unplated electrode tip.

  1. Ice sheet in peril

    DEFF Research Database (Denmark)

    Hvidberg, Christine Schøtt

    2016-01-01

    Earth's large ice sheets in Greenland and Antarctica are major contributors to sea level change. At present, the Greenland Ice Sheet (see the photo) is losing mass in response to climate warming in Greenland (1), but the present changes also include a long-term response to past climate transitions...

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This ... To locate a medical imaging or radiation oncology provider in your community, you can search the ACR- ...

  3. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... Videos About Us News Physician Resources Professions Site Index A-Z Transjugular Intrahepatic Portosystemic Shunt (TIPS) Transjugular ... in the portal vein system. This pressure buildup can cause blood to flow backward from the liver ...

  4. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... physician will numb an area just above your right collarbone with a local anesthetic . A very small ...

  5. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... story about radiology? Share your patient story here Images × Image Gallery Radiologist and patient consultation. View full size ... X-Ray and CT Exams Contrast Materials Venography Images related to Transjugular Intrahepatic Portosystemic Shunt (TIPS) Sponsored ...

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... in the chest or abdomen. This condition is most commonly seen in adults, often as a result ... minimally invasive procedures such as a TIPS are most often performed by a specially trained interventional radiologist ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... and lengthy procedures requiring extended fluoroscopy use) death (rare) top of page What are the limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... less likely to require a TIPS. top of page What are some common uses of the procedure? A ... gown to wear during the procedure. top of page What does the equipment look like? In this procedure, ...

  9. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... the hepatic vein in the liver. A small metal device called a stent is placed to keep ... open by the placement of a small, tubular metal device commonly called a stent . During a TIPS ...

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... of bleeding that can occur can sometimes be life threatening and those patients are monitored in intensive ... invasive procedure that typically has a shorter recovery time than surgery. Your TIPS should have less of ...

  11. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... while avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and esophagus in patients ... site. Using ultrasound, the doctor will identify your internal jugular vein , which is situated above your collarbone, ...

  12. Choking and Strangulation Prevention Tips

    Science.gov (United States)

    ... Safety Sponsors Recalls Media Center Blog Videos Newsletter facebook twitter instagram pinterest gplus youtube Search Menu Why It Matters ... Safety Sponsors Recalls Media Center Blog Videos Newsletter facebook twitter instagram pinterest gplus youtube Sign up for quick tips ...

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... hepatic vein to identify the portal venous system. Access is then gained from the hepatic vein into ... TIPS procedure to make sure that it remains open and functions properly. top of page Who interprets ...

  14. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This page ... American College of Radiology (ACR) and the Radiological Society of North America (RSNA), comprising physicians with expertise ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... the portal system using a TIPS needle (a special long needle extending from the neck into the ... Encephalopathy can be treated with certain medications, a special diet or, by revising the stent, but sometimes ...

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... TIPS may successfully reduce internal bleeding in the stomach and esophagus in patients with cirrhosis. Tell your ... the liver into the veins of the spleen, stomach, lower esophagus, and intestines, causing enlarged vessels, bleeding ...

  17. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... in an hour or two but may take up to several hours depending on the complexity of ... normal activities in seven to 10 days. Follow-up ultrasounds will be performed frequently after the TIPS ...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... portal vein to the hepatic vein in the liver. A small metal device called a stent is ... bowel back to the heart while avoiding the liver. TIPS may successfully reduce internal bleeding in the ...

  19. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... of an effect than open surgical bypass on future liver transplantation surgery because the abdomen has not ... TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This page ...

  20. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... blood draining from the bowel back to the heart while avoiding the liver. TIPS may successfully reduce ... blood away from the liver back to the heart). A stent is then placed in this tunnel ...

  1. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... you are pregnant and discuss any recent illnesses, medical conditions, allergies and medications you’re taking. You ... with ascites or variceal bleeding resistant to traditional medical treatments. The greatest difference in performing TIPS in ...

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver ... have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media Radiation Dose ...

  3. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... bear denotes child-specific content. Related Articles and Media Radiation Dose in X-Ray and CT Exams Contrast Materials Venography Images related to Transjugular Intrahepatic Portosystemic Shunt (TIPS) Sponsored ...

  4. Search Tips: MedlinePlus

    Science.gov (United States)

    ... of this page: https://medlineplus.gov/searchtips.html Search Tips To use the sharing features on this page, please enable JavaScript. How do I search MedlinePlus? The search box appears at the top ...

  5. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... to the heart while avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and ... conditions, allergies and medications you’re taking. You may be advised to stop taking aspirin, nonsteroidal anti- ...

  6. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... risks. Other possible complications of the procedure include: fever muscle stiffness in the neck bruising on the ... filtered out by the liver. The TIPS may cause too much of these substances to bypass the ...

  7. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... avoiding the liver. TIPS may successfully reduce internal bleeding in the stomach and esophagus in patients with ... stomach, lower esophagus, and intestines, causing enlarged vessels, bleeding and the accumulation of fluid in the chest ...

  8. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... system. This pressure buildup can cause blood to flow backward from the liver into the veins of ... does the procedure work? A TIPS reroutes blood flow in the liver and reduces abnormally high blood ...

  9. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... liver back to the heart. top of page How should I prepare? You should report to your ... heart beat and blood pressure. top of page How does the procedure work? A TIPS reroutes blood ...

  10. Computerized automatic tip scanning operation

    International Nuclear Information System (INIS)

    Nishikawa, K.; Fukushima, T.; Nakai, H.; Yanagisawa, A.

    1984-01-01

    In BWR nuclear power stations the Traversing Incore Probe (TIP) system is one of the most important components in reactor monitoring and control. In previous TIP systems, however, operators have suffered from the complexity of operation and long operation time required. The system presented in this paper realizes the automatic operation of the TIP system by monitoring and driving it with a process computer. This system significantly reduces the burden on customer operators and improves plant efficiency by simplifying the operating procedure, augmenting the accuracy of the measured data, and shortening operating time. The process computer is one of the PODIA (Plant Operation by Displayed Information Automation) systems. This computer transfers control signals to the TIP control panel, which in turn drives equipment by microprocessor control. The process computer contains such components as the CRT/KB unit, the printer plotter, the hard copier, and the message typers required for efficient man-machine communications. Its operation and interface properties are described

  11. Tips to Prevent Tick Bites

    Science.gov (United States)

    Using the right insect repellent and other preventive actions can discourage ticks, mosquitoes, and other biting insects from landing on you. Tips include avoiding tick habitats and minimizing exposed skin.

  12. Tips to Prevent Mosquito Bites

    Science.gov (United States)

    Using the right insect repellent and other preventive actions can discourage mosquitoes from landing on you. Tips include removing mosquito habitats such as standing water, minimizing exposed skin, and staying indoors while mosquitoes are most active.

  13. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... Patients who typically need a TIPS have portal hypertension , meaning they have increased pressure in the portal ... leading to cirrhosis (scarring of the liver). Portal hypertension can also occur in children, although children are ...

  14. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... deeply you are sedated. When the needle is advanced through the liver and the pathway is expanded ... are the limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening ...

  15. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... in creating the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient ... Send us your feedback Did you find the information you were looking for? Yes No Please type ...

  16. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

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    Full Text Available ... of page What are some common uses of the procedure? A TIPS is used to treat the ... during the procedure. top of page What does the equipment look like? In this procedure, x-ray ...

  17. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... is completed. top of page What are the benefits vs. risks? Benefits A TIPS is designed to produce the same ... urgent intervention heart arrhythmias or congestive heart failure radiation injury to the skin is a rare complication ( ...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... local anesthetic medications, general anesthesia or to contrast materials containing iodine (sometimes referred to as "dye" or " ... the placement of the TIPS stent, a contrast material will be injected in the hepatic vein to ...

  19. Evaluation of Aircraft Wing-Tip Vortex Using PIV

    Science.gov (United States)

    Alsayed, Omer A.; Asrar, Waqar; Omar, Ashraf A.

    2010-06-01

    The formation and development of a wing-tip vortex in a near and extended near filed were studied experimentally. Particle image velocimetry was used in a wind tunnel to measure the tip vortex velocity field and hence investigate the flow structure in a wake of aircraft half-wing model. The purpose of this investigation is to evaluate the main features of the lift generated vortices in order to find ways to alleviate hazardous wake vortex encounters for follower airplanes during start and approach such that the increase in airport capacity can be achieved. First the wake structure at successive downstream planes crosswise to the axis of the wake vortices was investigated by measuring parameters such as core radius, maximum tangential velocities, vorticities and circulation distributions. The effect of different angles of attack setting on vortex parameters was examined at one downstream location. In very early stages the vortex sheet evolution makes the tip vortex to move inward and to the suction side of the wing. While the core radius and circulation distributions hardly vary with the downstream distance, noticeable differences for the same vortex parameters at different angles of attack settings were observed. The center of the wing tip vortices scatter in a circle of radius nearly equal to 1% of the mean wing chord and wandering amplitudes shows no direct dependence on the vortex strength but linearly increase with the downstream distance.

  20. Tip model of cold fission

    International Nuclear Information System (INIS)

    Goennenwein, F.; Boersig, B.

    1991-01-01

    Cold fission is defined to be the limiting case of nuclear fission where virtually all of the available energy is converted into the total kinetic energy of the fragments. The fragments have, therefore, to be born in or at least close to their respective ground states. Starting from the viewpoint that cold fission corresponds to most compact scission configurations, energy constraints have been exploited to calculate minimum tip distances between the two nascent fragments in binary fission. Crucial input parameters to this tip model of cold fission are the ground-state deformations of fragment nuclei. It is shown that the minimum tip distances being compatible with energy conservation vary strongly with both the mass and charge fragmentation of the fission prone nucleus. The tip distances refer to nuclei with equivalent sharp surfaces. In keeping with the size of the surface width of leptodermous nuclei, only configurations where the tip distances are smaller than a few fm may be considered as valid scission configurations. From a comparison with experimental data on cold fission this critical tip distance appears to be 3.0 fm for the model parameters chosen. Whenever the model calculation yields tip distances being smaller than the critical value, a necessary condition for attaining cold fission is considered to be fulfilled. It is shown that this criterion allows to understand in fair agreement with experiment which mass fragmentations are susceptible to lead to cold fission and which fragment-charge divisions are the most favored in each isobaric mass chain. Being based merely on energy arguments, the model cannot aim at predicting fragment yields in cold fission. However, the tip model proposed appears well suited to delineate the phase space where cold fission phenomena may come into sight. (orig.)

  1. Patterning of Structurally Anisotropic Composite Hydrogel Sheets.

    Science.gov (United States)

    Prince, Elisabeth; Alizadehgiashi, Moien; Campbell, Melissa; Khuu, Nancy; Albulescu, Alexandra; De France, Kevin; Ratkov, Dimitrije; Li, Yunfeng; Hoare, Todd; Kumacheva, Eugenia

    2018-04-09

    Compositional and structural patterns play a crucial role in the function of many biological tissues. In the present work, for nanofibrillar hydrogels formed by chemically cross-linked cellulose nanocrystals (CNC) and gelatin, we report a microextrusion-based 3D printing method to generate structurally anisotropic hydrogel sheets with CNCs aligned in the direction of extrusion. We prepared hydrogels with a uniform composition, as well as hydrogels with two different types of compositional gradients. In the first type of gradient hydrogel, the composition of the sheet varied parallel to the direction of CNC alignment. In the second hydrogel type, the composition of the sheet changed orthogonally to the direction of CNC alignment. The hydrogels exhibited gradients in structure, mechanical properties, and permeability, all governed by the compositional patterns, as well as cytocompatibility. These hydrogels have promising applications for both fundamental research and for tissue engineering and regenerative medicine.

  2. Risk-analysis of global climate tipping points

    Energy Technology Data Exchange (ETDEWEB)

    Frieler, Katja; Meinshausen, Malte; Braun, N. [Potsdam Institute for Climate Impact Research e.V., Potsdam (Germany). PRIMAP Research Group] [and others

    2012-09-15

    There are many elements of the Earth system that are expected to change gradually with increasing global warming. Changes might prove to be reversible after global warming returns to lower levels. But there are others that have the potential of showing a threshold behavior. This means that these changes would imply a transition between qualitatively disparate states which can be triggered by only small shifts in background climate (2). These changes are often expected not to be reversible by returning to the current level of warming. The reason for that is, that many of them are characterized by self-amplifying processes that could lead to a new internally stable state which is qualitatively different from before. There are different elements of the climate system that are already identified as potential tipping elements. This group contains the mass losses of the Greenland and the West-Antarctic Ice Sheet, the decline of the Arctic summer sea ice, different monsoon systems, the degradation of coral reefs, the dieback of the Amazon rainforest, the thawing of the permafrost regions as well as the release of methane hydrates (3). Crucially, these tipping elements have regional to global scale effects on human society, biodiversity and/or ecosystem services. Several examples may have a discernable effect on global climate through a large-scale positive feedback. This means they would further amplify the human induced climate change. These tipping elements pose risks comparable to risks found in other fields of human activity: high-impact events that have at least a few percent chance to occur classify as high-risk events. In many of these examples adaptation options are limited and prevention of occurrence may be a more viable strategy. Therefore, a better understanding of the processes driving tipping points is essential. There might be other tipping elements even more critical but not yet identified. These may also lie within our socio-economic systems that are

  3. Insurance Discounts: Traffic Safety Tips

    Science.gov (United States)

    1996-01-01

    This fact sheet, NHTSA Facts: Summer 1996, discusses automobile insurance discounts. It relates how to obtain a discount, and details what factors can influence insurance premiums. It notes that discounts for safety features vary from insurance compa...

  4. Girlfriends' Health and Safety Tips

    Science.gov (United States)

    ... Professionals Girlfriends’ Health Heart Disease Prevention Mother’s Day Weddings Multimedia Badges and Buttons Podcasts National Women’s Health ... Disease Fact Sheet Women's Health Healthy Weight Lesbian, Gay, Bisexual, and Transgender Health Minority Health Preconception Health ...

  5. Anesthesia Fact Sheet

    Science.gov (United States)

    ... Education About NIGMS NIGMS Home > Science Education > Anesthesia Anesthesia Tagline (Optional) Middle/Main Content Area En español ... Version (464 KB) Other Fact Sheets What is anesthesia? Anesthesia is a medical treatment that prevents patients ...

  6. Global ice sheet modeling

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, T.J.; Fastook, J.L. [Univ. of Maine, Orono, ME (United States). Institute for Quaternary Studies

    1994-05-01

    The University of Maine conducted this study for Pacific Northwest Laboratory (PNL) as part of a global climate modeling task for site characterization of the potential nuclear waste respository site at Yucca Mountain, NV. The purpose of the study was to develop a global ice sheet dynamics model that will forecast the three-dimensional configuration of global ice sheets for specific climate change scenarios. The objective of the third (final) year of the work was to produce ice sheet data for glaciation scenarios covering the next 100,000 years. This was accomplished using both the map-plane and flowband solutions of our time-dependent, finite-element gridpoint model. The theory and equations used to develop the ice sheet models are presented. Three future scenarios were simulated by the model and results are discussed.

  7. Global ice sheet modeling

    International Nuclear Information System (INIS)

    Hughes, T.J.; Fastook, J.L.

    1994-05-01

    The University of Maine conducted this study for Pacific Northwest Laboratory (PNL) as part of a global climate modeling task for site characterization of the potential nuclear waste respository site at Yucca Mountain, NV. The purpose of the study was to develop a global ice sheet dynamics model that will forecast the three-dimensional configuration of global ice sheets for specific climate change scenarios. The objective of the third (final) year of the work was to produce ice sheet data for glaciation scenarios covering the next 100,000 years. This was accomplished using both the map-plane and flowband solutions of our time-dependent, finite-element gridpoint model. The theory and equations used to develop the ice sheet models are presented. Three future scenarios were simulated by the model and results are discussed

  8. Structural Biology Fact Sheet

    Science.gov (United States)

    ... beta sheets (blue; thinner, tangled strands). Credit: RCSB Protein Data Bank. Even though proteins are strings of amino acids, ... structure of more than 122,000 proteins. The Protein Data Bank stores these structures and gives scientists access to ...

  9. Sepsis Fact Sheet

    Science.gov (United States)

    ... Education About NIGMS NIGMS Home > Science Education > Sepsis Sepsis Tagline (Optional) Middle/Main Content Area PDF Version ( ... KB) En español Other Fact Sheets What is sepsis? Sepsis is a serious medical condition. It is ...

  10. Respirator Fact Sheet

    Science.gov (United States)

    ... to protect myself, my family, and/or my employees? If available and used correctly, a respirator can ... Respirator Fact Sheet [PDF - 706 KB] Follow NIOSH Facebook Flickr Pinterest Twitter YouTube NIOSH Homepage NIOSH A- ...

  11. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  12. Medicines and Bone Loss

    Science.gov (United States)

    Fact Sheet Medici a ne n s d Bone Loss Some types of medicines can cause bone loss, making your bones weak, if used for a long time. Use over a short time ... old bone and replaces it with new bone. Bone loss occurs when old bone breaks down faster than ...

  13. Nanobits: customizable scanning probe tips

    DEFF Research Database (Denmark)

    Kumar, Rajendra; Shaik, Hassan Uddin; Sardan Sukas, Özlem

    2009-01-01

    We present here a proof-of-principle study of scanning probe tips defined by planar nanolithography and integrated with AFM probes using nanomanipulation. The so-called 'nanobits' are 2-4 mu m long and 120-150 nm thin flakes of Si3N4 or SiO2, fabricated by electron beam lithography and standard...... or dislocation of the tips of the nanobit after several scans. This approach allows an unprecedented freedom in adapting the shape and size of scanning probe tips to the surface topology or to the specific application....... silicon processing. Using a microgripper they were detached from an array and fixed to a standard pyramidal AFM probe or alternatively inserted into a tipless cantilever equipped with a narrow slit. The nanobit-enhanced probes were used for imaging of deep trenches, without visible deformation, wear...

  14. ZBrush Professional Tips and Techniques

    CERN Document Server

    Gaboury, Paul

    2012-01-01

    Learn to work effectively and creatively with all versions of ZBrush! ZBrush is used by top artists in Hollywood to model and sculpt characters in such films as Avatar, Iron Man, and Pirates of the Caribbean. In addition, this amazing technology is also used in jewelry design, forensic science, aerospace, video games, toy creation, and the medical field. Written by Pixologic's in-house ZBrush expert Paul Gaboury, this full-color, beautifully illustrated guide provides you with the ultimate tips and tricks to maximize your use of all versions of ZBrush. Reveals numerous little-known tips and tr

  15. Office 2010 Visual Quick Tips

    CERN Document Server

    Gunter, Sherry Kinkoph

    2010-01-01

    Get more done in Office 2010 in less time with these Quick Tips!. Whether you're new to Microsoft Office or updating from older versions, this is the perfect resource to get you quickly up to speed on Office 2010. Every application is covered, including Word, Excel, PowerPoint, Outlook, and Publisher. Full-color screenshots and numbered steps clearly explain dozens of features and functions-while quick shortcuts, tips, and tricks help you save time and boost productivity. You'll also find great new ways to access and use some Office apps right from the Web.: Walks you through dozens of new fea

  16. The effect of broken stringers on the stress intensity factor for a uniformly stiffened sheet containing a crack

    Science.gov (United States)

    Poe, C. C., Jr.

    1973-01-01

    A linear elastic stress analysis was made of a centrally cracked sheet stiffened by riveted, uniformly spaced and sized stringers. The stress intensity factor for the sheet and the load concentration factor for the most highly loaded stringer were determined for various numbers of broken stringers. A broken stringer causes the stress intensity factor to be very high when the crack tip is near the broken stringer, but causes little effect when the crack tip extends beyond several intact stringers. A broken stringer also causes an increase in the load concentration factor of the adjacent stringers. The calculated residual strengths and fatigue-crack-growth lives of a stiffened aluminum sheet with a broken stringer were only slightly less than a sheet with all intact stringers, and were still much higher than those of an unstiffened sheet.

  17. The tip of the iceberg

    DEFF Research Database (Denmark)

    Bjørst, Lill Rastad

    2010-01-01

      Abstract: The tip of the iceberg: Ice as a nonhuman actor of the climate change debate   The global climate change debate has the Arctic as a core region of concern and ice has become a central aspect of discourses. This article discusses ice representations from six different contexts linked...

  18. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... in creating the TIPS. top of page Additional Information and Resources Society of Interventional Radiology (SIR) - Patient Center This page ... of Use | Links | Site Map Copyright © 2018 ... To help ensure current and accurate information, we do not permit copying but encourage linking ...

  19. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... pressure. top of page How does the procedure work? A TIPS reroutes blood flow in the liver and reduces abnormally high blood pressure in the veins of the stomach, esophagus, bowel and liver, reducing the risk of bleeding from enlarged veins across the esophagus ...

  20. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available ... failure is severe, a TIPS may not be the best use and a different procedure may be needed to control your symptoms. They are also at risk for encephalopathy , which is an alteration of normal brain function that can lead to confusion. This is ...

  1. Food Allergy: Tips to Remember

    Science.gov (United States)

    ... or get better on their own. Outgrowing Food Allergies Most children outgrow their allergies to cow’s milk, egg, soy ... can help you learn when you or your child’s food allergies are resolving with time. Healthy Tips • Always ask ...

  2. Transjugular Intrahepatic Portosystemic Shunt (TIPS)

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... limitations of TIPS? Patients with more advanced liver disease are at greater risk for worsening liver failure ...

  3. Assigning Effective Homework. Classroom Tips

    Science.gov (United States)

    American Federation of Teachers (NJ), 2010

    2010-01-01

    Each new school year brings high hopes, great expectations and challenges for both new and seasoned educators. The American Federation of Teachers (AFT) has developed a series called "Classroom Tips" to help educators start the year right and anticipate the year ahead. Over the past 40 years, most research studies on homework have found that…

  4. Predicting casualties implied by TIPs

    Science.gov (United States)

    Trendafiloski, G.; Wyss, M.; Wyss, B. M.

    2009-12-01

    When an earthquake is predicted, forecast, or expected with a higher than normal probability, losses are implied. We estimated the casualties (fatalities plus injured) that should be expected if earthquakes in TIPs (locations of Temporarily Increased Probability of earthquakes) defined by Kossobokov et al. (2009) should occur. We classified the predictions of losses into the categories red (more than 400 fatalities or more than 1,000 injured), yellow (between 100 and 400 fatalities), green (fewer than 100 fatalities), and gray (undetermined). TIPs in Central Chile, the Philippines, Papua, and Taiwan are in the red class, TIPs in Southern Sumatra, Nicaragua, Vanatu, and Honshu in the yellow class, and TIPs in Tonga, Loyalty Islands, Vanatu, S. Sandwich Islands, Banda Sea, and the Kuriles, are classified as green. TIPs where the losses depend moderately on the assumed point of major energy release were classified as yellow; TIPs such as in the Talaud Islands and in Tonga, where the losses depend very strongly on the location of the epicenter, were classified as gray. The accuracy of loss estimates after earthquakes with known hypocenter and magnitude are affected by uncertainties in transmission and soil properties, the composition of the building stock, the population present, and the method by which the numbers of casualties are calculated. In the case of TIPs, uncertainties in magnitude and location are added, thus we calculate losses for a range of these two parameters. Therefore, our calculations can only be considered order of magnitude estimates. Nevertheless, our predictions can come to within a factor of two of the observed numbers, as in the case of the M7.6 earthquake of October 2005 in Pakistan that resulted in 85,000 fatalities (Wyss, 2005). In subduction zones, the geometrical relationship between the earthquake source capable of a great earthquake and the population is clear because there is only one major fault plane available, thus the epicentral

  5. Mini-flared Kelman tip, reverse tip, and sidewinder tip with torsional phaco: a prospective randomized comparative study

    Directory of Open Access Journals (Sweden)

    Wilson Takashi Hida

    2015-02-01

    Full Text Available Purpose: To compare the efficiency of surgical procedures using three phaco tip designs in torsional phacoemulsification using the bevel-down technique. Methods: In this prospective, comparative, masked study, patients were randomly assigned to have torsional coaxial microincision cataract surgery using the mini-flared 45-degree Kelman tip, reversed mini-flared 30-degree Kelman tip, or Sidewinder 30-degree Kelman tip. Clinical measurements included preoperative and 3-month postoperative corrected distance visual acuity (CDVA, endothelial cell counts (ECC, and preoperative and 1-day postoperative central corneal thickness (CCT. Intraoperative measurements included phaco time, torsional time, aspiration time, case time, cumulative dissipated energy (CDE, and balanced salt solution volume (BSS. Results: The study evaluated 150 eyes of 150 patients. Intraoperatively, there was no statistically significant difference in cumulative dissipated energy, case time, torsional time, and aspiration time between the three tip configurations. However, less phaco time was used with the mini-flared 45-degree Kelman tip (p=0.02 than that with the Sidewinder 30-degree Kelman tip or reversed mini-flared 30-degree Kelman tip. The mini-flared 45-degree Kelman tip and the reversed mini-flared 30-degree Kelman tip required significantly less balanced salt solution volume than that required by the Sidewinder 30-degree Kelman tip (p=0.009. There was no statistically significant difference in corrected distance visual acuity and endothelial cell counts between tips 3 months postoperatively (p>0.05. Conclusion: All three tips were effective with no intraoperative complications. When using torsional phacoemulsification through microincisions and the prefracture technique with the bevel-down technique, the mini-flared 45-degree Kelman tip required a lower mean phaco time than the reversed mini-flared 30-degree Kelman tip and the Sidewinder 30-degree Kelman tip.

  6. Safety advice sheets

    CERN Multimedia

    HSE Unit

    2013-01-01

    You never know when you might be faced with questions such as: when/how should I dispose of a gas canister? Where can I find an inspection report? How should I handle/store/dispose of a chemical substance…?   The SI section of the DGS/SEE Group is primarily responsible for safety inspections, evaluating the safety conditions of equipment items, premises and facilities. On top of this core task, it also regularly issues “Safety Advice Sheets” on various topics, designed to be of assistance to users but also to recall and reinforce safety rules and procedures. These clear and concise sheets, complete with illustrations, are easy to display in the appropriate areas. The following safety advice sheets have been issued so far: Other sheets will be published shortly. Suggestions are welcome and should be sent to the SI section of the DGS/SEE Group. Please send enquiries to general-safety-visits.service@cern.ch.

  7. Side Effects of HIV Medicines: HIV and Hepatotoxicity

    Science.gov (United States)

    ... Apps skip to content Side Effects of HIV Medicines Home Understanding HIV/AIDS Fact Sheets HIV and ... Latent HIV Reservoir? HIV Testing FDA-Approved HIV Medicines What is an Investigational HIV Drug? What is ...

  8. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-02

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. Written for the general public, the EIA publication Energy Information Sheets was developed to provide information on various aspects of fuel production, prices, consumption and capability. The information contained herein pertains to energy data as of December 1991. Additional information on related subject matter can be found in other EIA publications as referenced at the end of each sheet.

  9. Parenting Tips: How to Improve Toddler Behavior

    Science.gov (United States)

    ... issues. To encourage listening and cooperation, follow these parenting tips. By Mayo Clinic Staff Life can be ... and a degree of routine. Consider these practical parenting tips. Make sure your displays of affection for ...

  10. Tips for Good Oral Health during Pregnancy

    Science.gov (United States)

    Tips for Good Oral Health During Pregnancy B elow are tips for taking care of your oral health while you are pregnant. Getting oral health care, practicing good oral hygiene, eating healthy foods, ...

  11. School Avoidance: Tips for Concerned Parents

    Science.gov (United States)

    ... Email Print Share School Avoidance: Tips for Concerned Parents Page Content ​School avoidance – sometimes called school refusal ... school bully) Actual physical harm Tips for Concerned Parents: As a first step, the management of school ...

  12. Radiofrequency Wire Recanalization of Chronically Thrombosed TIPS

    Energy Technology Data Exchange (ETDEWEB)

    Majdalany, Bill S., E-mail: bmajdala@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States); Elliott, Eric D., E-mail: eric.elliott@osumc.edu [The Ohio State University Wexner Medical Center, Division of Interventional Radiology, Department of Radiology (United States); Michaels, Anthony J., E-mail: Anthony.michaels@osumc.edu; Hanje, A. James, E-mail: James.Hanje@osumc.edu [The Ohio State University Wexner Medical Center, Division of Gastroenterology and Hepatology, Department of Medicine (United States); Saad, Wael E. A., E-mail: wsaad@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States)

    2016-07-15

    Radiofrequency (RF) guide wires have been applied to cardiac interventions, recanalization of central venous thromboses, and to cross biliary occlusions. Herein, the use of a RF wire technique to revise chronically occluded transjugular intrahepatic portosystemic shunts (TIPS) is described. In both cases, conventional TIPS revision techniques failed to revise the chronically thrombosed TIPS. RF wire recanalization was successfully performed through each of the chronically thrombosed TIPS, demonstrating initial safety and feasibility in this application.

  13. Fuels planning: science synthesis and integration; social issues fact sheet 12: Keys to successful collaboration

    Science.gov (United States)

    Christine Esposito

    2006-01-01

    Collaborating on fire and fuels management with a host of public and private partners may seem like an impossible undertaking, and presents many challenges. This fact sheet reviews tips for what to focus on as you embark on a collaborative fuels management project.Other...

  14. Injector tip for an internal combustion engine

    Science.gov (United States)

    Shyu, Tsu Pin; Ye, Wen

    2003-05-20

    This invention relates to a the tip structure of a fuel injector as used in a internal combustion engine. Internal combustion engines using Homogeneous Charge Compression Ignition (HCCI) technology require a tip structure that directs fuel spray in a downward direction. This requirement necessitates a tip design that is capable of withstanding mechanical stresses associated with the design.

  15. Ice Sheets & Ice Cores

    DEFF Research Database (Denmark)

    Mikkelsen, Troels Bøgeholm

    Since the discovery of the Ice Ages it has been evident that Earth’s climate is liable to undergo dramatic changes. The previous climatic period known as the Last Glacial saw large oscillations in the extent of ice sheets covering the Northern hemisphere. Understanding these oscillations known...

  16. Pseudomonas - Fact Sheet

    OpenAIRE

    Public Health Agency

    2012-01-01

    Fact sheet on Pseudomonas, including:What is Pseudomonas?What infections does it cause?Who is susceptible to pseudomonas infection?How will I know if I have pseudomonas infection?How can Pseudomonas be prevented from spreading?How can I protect myself from Pseudomonas?How is Pseudomonas infection treated?

  17. Collisionless current sheet equilibria

    Science.gov (United States)

    Neukirch, T.; Wilson, F.; Allanson, O.

    2018-01-01

    Current sheets are important for the structure and dynamics of many plasma systems. In space and astrophysical plasmas they play a crucial role in activity processes, for example by facilitating the release of magnetic energy via processes such as magnetic reconnection. In this contribution we will focus on collisionless plasma systems. A sensible first step in any investigation of physical processes involving current sheets is to find appropriate equilibrium solutions. The theory of collisionless plasma equilibria is well established, but over the past few years there has been a renewed interest in finding equilibrium distribution functions for collisionless current sheets with particular properties, for example for cases where the current density is parallel to the magnetic field (force-free current sheets). This interest is due to a combination of scientific curiosity and potential applications to space and astrophysical plasmas. In this paper we will give an overview of some of the recent developments, discuss their potential applications and address a number of open questions.

  18. Ethanol Basics (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2015-01-01

    Ethanol is a widely-used, domestically-produced renewable fuel made from corn and other plant materials. More than 96% of gasoline sold in the United States contains ethanol. Learn more about this alternative fuel in the Ethanol Basics Fact Sheet, produced by the U.S. Department of Energy's Clean Cities program.

  19. Rubella - Fact Sheet for Parents

    Science.gov (United States)

    ... and 4 through 6 years Fact Sheet for Parents Color [2 pages] Español: Rubéola The best way ... according to the recommended schedule. Fact Sheets for Parents Diseases and the Vaccines that Prevent Them Chickenpox ...

  20. CURRENT SHEET ENERGETICS, FLARE EMISSIONS, AND ENERGY PARTITION IN A SIMULATED SOLAR ERUPTION

    International Nuclear Information System (INIS)

    Reeves, Katharine K.; Linker, Jon A.; Mikic, Zoran; Forbes, Terry G.

    2010-01-01

    We investigate coronal energy flow during a simulated coronal mass ejection (CME). We model the CME in the context of the global corona using a 2.5D numerical MHD code in spherical coordinates that includes coronal heating, thermal conduction, and radiative cooling in the energy equation. The simulation domain extends from 1 to 20 R s . To our knowledge, this is the first attempt to apply detailed energy diagnostics in a flare/CME simulation when these important terms are considered in the context of the MHD equations. We find that the energy conservation properties of the code are quite good, conserving energy to within 4% for the entire simulation (more than 6 days of real time). We examine the energy release in the current sheet as the eruption takes place, and find, as expected, that the Poynting flux is the dominant carrier of energy into the current sheet. However, there is a significant flow of energy out of the sides of the current sheet into the upstream region due to thermal conduction along field lines and viscous drag. This energy outflow is spatially partitioned into three separate components, namely, the energy flux flowing out the sides of the current sheet, the energy flowing out the lower tip of the current sheet, and the energy flowing out the upper tip of the current sheet. The energy flow through the lower tip of the current sheet is the energy available for heating of the flare loops. We examine the simulated flare emissions and energetics due to the modeled CME and find reasonable agreement with flare loop morphologies and energy partitioning in observed solar eruptions. The simulation also provides an explanation for coronal dimming during eruptions and predicts that the structures surrounding the current sheet are visible in X-ray observations.

  1. Phenomenological Model of Current Sheet Canting in Pulsed Electromagnetic Accelerators

    Science.gov (United States)

    Markusic, Thomas; Choueiri, E. Y.

    2003-01-01

    The phenomenon of current sheet canting in pulsed electromagnetic accelerators is the departure of the plasma sheet (that carries the current) from a plane that is perpendicular to the electrodes to one that is skewed, or tipped. Review of pulsed electromagnetic accelerator literature reveals that current sheet canting is a ubiquitous phenomenon - occurring in all of the standard accelerator geometries. Developing an understanding of current sheet canting is important because it can detract from the propellant sweeping capabilities of current sheets and, hence, negatively impact the overall efficiency of pulsed electromagnetic accelerators. In the present study, it is postulated that depletion of plasma near the anode, which results from axial density gradient induced diamagnetic drift, occurs during the early stages of the discharge, creating a density gradient normal to the anode, with a characteristic length on the order of the ion skin depth. Rapid penetration of the magnetic field through this region ensues, due to the Hall effect, leading to a canted current front ahead of the initial current conduction channel. In this model, once the current sheet reaches appreciable speeds, entrainment of stationary propellant replenishes plasma in the anode region, inhibiting further Hall-convective transport of the magnetic field; however, the previously established tilted current sheet remains at a fairly constant canting angle for the remainder of the discharge cycle, exerting a transverse J x B force which drives plasma toward the cathode and accumulates it there. This proposed sequence of events has been incorporated into a phenomenological model. The model predicts that canting can be reduced by using low atomic mass propellants with high propellant loading number density; the model results are shown to give qualitative agreement with experimentally measured canting angle mass dependence trends.

  2. Single sheet iron oxides

    DEFF Research Database (Denmark)

    Yin, Zhou

    activity. LDH single sheets have been reported to be effective sorbents, catalysts in electrochemical and photochemical reactions, and building thin films together with other nanomaterials for designing new functionalities. Here we focus on the delamination of FeII-FeIII LDHs into single sheet iron oxide...... was rapid compared to other iron oxides, reaching equilibrium within 60 minutes. Arsenic sorption and acid-base titration data could be successfully described with a 1pk Basic Stern Model (BSM). The point of zero charge was around 8. The intrinsic surface complexation equilibrium constants (log K...... became abundant at low pH. (3) Electrochemical reduction of chlorinated compounds using an SSI modified electrode. Here, the electrochemical reactivity of SSIs coated on indium tin oxide coated glass electrodes was investigated. Iron on the SSI modified electrode showed a typical Cyclic Voltammetry...

  3. Film sheet cassette

    International Nuclear Information System (INIS)

    1981-01-01

    A novel film sheet cassette is described for handling CAT photographic films under daylight conditions and facilitating their imaging. A detailed description of the design and operation of the cassette is given together with appropriate illustrations. The resulting cassette is a low-cost unit which is easily constructed and yet provides a sure light-tight seal for the interior contents of the cassette. The individual resilient fingers on the light-trap permit the ready removal of the slide plate for taking pictures. The stippled, non-electrostatic surface of the pressure plate ensures an air layer and free slidability of the film for removal and withdrawal of the film sheet. The advantage of the daylight system is that a darkroom need not be used for inserting and removing the film in and out of the cassette resulting in a considerable time saving. (U.K.)

  4. Biomolecular Science (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-04-01

    A brief fact sheet about NREL Photobiology and Biomolecular Science. The research goal of NREL's Biomolecular Science is to enable cost-competitive advanced lignocellulosic biofuels production by understanding the science critical for overcoming biomass recalcitrance and developing new product and product intermediate pathways. NREL's Photobiology focuses on understanding the capture of solar energy in photosynthetic systems and its use in converting carbon dioxide and water directly into hydrogen and advanced biofuels.

  5. Information sheets on energy

    International Nuclear Information System (INIS)

    2004-01-01

    These sheets, presented by the Cea, bring some information, in the energy domain, on the following topics: the world energy demand and the energy policy in France and in Europe, the part of the nuclear power in the energy of the future, the greenhouse gases emissions and the fight against the greenhouse effect, the carbon dioxide storage cost and the hydrogen economy. (A.L.B.)

  6. Windows 8 visual quick tips

    CERN Document Server

    McFedries, Paul

    2012-01-01

    Easy-in, easy-out format covers all the bells and whistles of Windows 8 If you want to learn how to work smarter and faster in Microsoft's Windows 8 operating system, this easy-to-use, compact guide delivers the goods. Designed for visual learners, it features short explanations and full-color screen shots on almost every page, and it's packed with timesaving tips and helpful productivity tricks. From enhancing performance and managing digital content to setting up security and much more, this handy guide will help you get more out of Windows 8. Uses full-color screen shots and short, step-by-

  7. Twitter Tips, Tricks, and Tweets

    CERN Document Server

    McFedries, Paul

    2010-01-01

    Maximize your fun and boost your productivity with this updated, full-color guide to tantalizing Twitter tips!. The popularity of Twitter continues to soar, and is fast becoming the most popular social networking site online. Whether you're looking to learn how to set up an account for the first time or are on the prowl for some cool third-party Twitter apps, this full-color guide will boost your entire Twitter experience. Allowing you to communicate with fellow Twitters within a 140-character limit, this fun and fascinating social networking tool is easier than maintaining a blog and quicker

  8. Rebleeding rates following TIPS for variceal hemorrhage in the Viatorr era: TIPS alone versus TIPS with variceal embolization.

    Science.gov (United States)

    Gaba, Ron C; Bui, James T; Cotler, Scott J; Kallwitz, Eric R; Mengin, Olga T; Martinez, Brandon K; Berkes, Jaime L; Carrillo, Tami C; Knuttinen, M Grace; Owens, Charles A

    2010-08-06

    To compare rebleeding rates following treatment of variceal hemorrhage with TIPS alone versus TIPS with variceal embolization in the covered stent-graft era. In this retrospective study, 52 patients (M:F 29:23, median age 52 years) with hepatic cirrhosis and variceal hemorrhage underwent TIPS insertion between 2003 and 2008. Median Child-Pugh and MELD scores were 8.5 and 13.5. Generally, 10-mm diameter TIPS were created using covered stent-grafts (Viatorr; W.L. Gore and Associates, Flagstaff, AZ). A total of 37 patients underwent TIPS alone, while 15 patients underwent TIPS with variceal embolization. The rates of rebleeding and survival were compared. All TIPS were technically successful. Median portosystemic pressure gradient reductions were 13 versus 11 mmHg in the embolization and non-embolization groups. There were no statistically significant differences in Child-Pugh and MELD score, or portosystemic pressure gradients between each group. A trend toward increased rebleeding was present in the non-embolization group, where 8/37 (21.6%) patients rebled while 1/15 (6.7%) patients in the TIPS with embolization group rebled (P = 0.159) during median follow-up periods of 199 and 252 days (P = 0.374). Rebleeding approached statistical significance among patients with acute hemorrhage, where 8/32 (25%) versus 0/14 (0%) rebled in the non-embolization and embolization groups (P = 0.055). A trend toward increased bleeding-related mortality was seen in the non-embolization group (P = 0.120). TIPS alone showed a high incidence of rebleeding in this series, whereas TIPS with variceal embolization resulted in reduced recurrent hemorrhage. The efficacy of embolization during TIPS performed for variceal hemorrhage versus TIPS alone should be further compared with larger prospective randomized trials.

  9. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  10. Dense sheet Z-pinches

    International Nuclear Information System (INIS)

    Tetsu, Miyamoto

    1999-01-01

    The steady state and quasi-steady processes of infinite- and finite-width sheet z-pinches are studied. The relations corresponding to the Bennett relation and Pease-Braginskii current of cylindrical fiber z-pinches depend on a geometrical factor in the sheet z-pinches. The finite-width sheet z-pinch is approximated by a segment of infinite-width sheet z-pinch, if it is wide enough, and corresponds to a number of (width/thickness) times fiber z-pinch plasmas of the diameter that equals the sheet thickness. If the sheet current equals this number times the fiber current, the plasma created in the sheet z-pinches is as dense as in the fiber z-pinches. The total energy of plasma and magnetic field per unit mass is approximately equal in both pinches. Quasi-static transient processes are different in several aspects from the fiber z-pinch. No radiation collapse occurs in the sheet z-pinch. The stability is improved in the sheet z-pinches. The fusion criterions and the experimental arrangements to produce the sheet z-pinches are also discussed. (author)

  11. Measuring Fan-Blade-Tip Displacements

    Science.gov (United States)

    Berry, Robert F., Jr.

    1988-01-01

    Magnets and Hall-effect transducers used to monitor tip-to-shroud clearances. Mounting permanent magnet in end of fan blade and monitoring tip-to-shroud distance by use of output of Hall-effect transducers affixed to surface of shroud. Transducers provide real-time information. By placing magnets in each fan-blade tip, complete set monitored sequentially as each blade rotates past sensor. Application in many rotating machines, providing surrounding materials nonmagnetic and temperatures not severe.

  12. Construction of three-dimensional vascularized cardiac tissue with cell sheet engineering.

    Science.gov (United States)

    Sakaguchi, Katsuhisa; Shimizu, Tatsuya; Okano, Teruo

    2015-05-10

    Construction of three-dimensional (3D) tissues with pre-isolated cells is a promising achievement for novel medicine and drug-discovery research. Our laboratory constructs 3D tissues with an innovative and unique method for layering multiple cell sheets. Cell sheets maintain a high-efficiently regenerating function, because of the higher cell density and higher transplantation efficiency, compared to other cell-delivery methods. Cell sheets have already been applied in clinical applications for regenerative medicine in treating patients with various diseases. Therefore, in our search to develop a more efficient treatment with cell sheets, we are constructing 3D tissues by layering cell sheets. Native animal tissues and organs have an abundance of capillaries to supply oxygen and nutrients, and to remove waste molecules. In our investigation of vascularized cardiac cell sheets, we have found that endothelial cells within cell sheets spontaneously form blood vessel networks as in vivo capillaries. To construct even thicker 3D tissues by layering multiple cell sheets, it is critical to have a medium or blood flow within the vascular networks of the cell sheets. Therefore, to perfuse medium or blood in the cell sheet vascular network to maintain the viability of all cells, we developed two types of vascular beds; (1) a femoral muscle-based vascular bed, and (2) a synthetic collagen gel-based vascular bed. Both vascular beds successfully provide the critical flow of culture medium, which allows 12-layer cell sheets to survive. Such bioreactor systems, when combined with cell sheet engineering techniques, have produced functional vascularized 3D tissues. Here we explain and discuss the various processes to obtain vascular networks by properly connecting cell sheets and the engineering of 3D tissues. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. A comparative study on cryopreservation of mint (Menth asp.) shoot tips

    Science.gov (United States)

    Mint is used in natural seasoning, traditional medicine, pharmaceuticals and cosmetics. In some countries it is grown on an industrial scale due to its economic importance; hence, preserving mint genetic resources is of value. We compared three cryopreservation techniques (T) using shoot tips of thr...

  14. Experiments on sheet metal shearing

    OpenAIRE

    Gustafsson, Emil

    2013-01-01

    Within the sheet metal industry, different shear cutting technologies are commonly used in several processing steps, e.g. in cut to length lines, slitting lines, end cropping etc. Shearing has speed and cost advantages over competing cutting methods like laser and plasma cutting, but involves large forces on the equipment and large strains in the sheet material.Numerical models to predict forces and sheared edge geometry for different sheet metal grades and different shear parameter set-ups a...

  15. Medicine and ionizing rays: a help sheet in analysing risks in radiotherapy and applicable texts; Medecine et rayonnements ionisants: fiche d'aide a l'analyse des risques en radiotherapie et textes applicables

    Energy Technology Data Exchange (ETDEWEB)

    Gauron, C. [Institut National de Recherche et de Securite, INRS, Dept. Etudes et Assistance Medicales, 75 - Paris (France)

    2007-07-01

    This document proposes a synthesis of useful knowledge for radioprotection in the case of external radiotherapy. In the first part, several aspects are considered: the concerned personnel, the course of treatment procedures, the hazards, the identification of the risk associated with ionizing radiation, the risk assessment and the exposure level determination, the strategy to control the risks (reduction of risks, technical measures concerning the installation or the personnel, teaching and information, prevention and medical monitoring), and risk control assessment. A second part indicates the various applicable legal and regulatory texts (European directives, law and decrees published by public authorities, and texts concerning the general principles in radioprotection, worker protection, specialists, medical devices, nuclear medicine and radiology)

  16. The tip of the iceberg

    DEFF Research Database (Denmark)

    Bjørst, Lill Rastad

    2010-01-01

      Abstract: The tip of the iceberg: Ice as a nonhuman actor of the climate change debate   The global climate change debate has the Arctic as a core region of concern and ice has become a central aspect of discourses. This article discusses ice representations from six different contexts linked...... to the 2009 United Nations Climate Change Conference (COP15) in Copenhagen. The author argues that even though the discussions often seem to be centred on ice alone, the latter gets inscribed in narratives and metaphors which have wider implications for how the Arctic and its Indigenous peoples...... are represented. Ice becomes a nonhuman actor, framing the discussions, acting in specific ways, and linking hybrid networks. Indeed it is used in diverse platforms by scientists, politicians, governments, NGOs, as well as Inuit hunters and fishermen...

  17. Twelve tips for using applied improvisation in medical education.

    Science.gov (United States)

    Hoffmann-Longtin, Krista; Rossing, Jonathan P; Weinstein, Elizabeth

    2018-04-01

    Future physicians will practice medicine in a more complex environment than ever, where skills of interpersonal communication, collaboration and adaptability to change are critical. Applied improvisation (or AI) is an instructional strategy which adapts the concepts of improvisational theater to teach these types of complex skills in other contexts. Unique to AI is its very active teaching approach, adapting theater games to help learners meet curricular objectives. In medical education, AI is particularly helpful when attempting to build students' comfort with and skills in complex, interpersonal behaviors such as effective listening, person-centeredness, teamwork and communication. This article draws on current evidence and the authors' experiences to present best practices for incorporating AI into teaching medicine. These practical tips help faculty new to AI get started by establishing goals, choosing appropriate games, understanding effective debriefing, considering evaluation strategies and managing resistance within the context of medical education.

  18. Twelve Tips for Effective Electronic Presentation.

    Science.gov (United States)

    Crosby, Joy

    1994-01-01

    Offers 12 tips for effective electronic presentation. This article is intended for readers who may be considering using electronic presentation for the first time. Offers reasons for its popularity and occasions when it may be used. The tips offer assistance in the design and presentation of electronic material. (LZ)

  19. Economics of tipping the climate dominoes

    Science.gov (United States)

    Lemoine, Derek; Traeger, Christian P.

    2016-05-01

    Greenhouse gas emissions can trigger irreversible regime shifts in the climate system, known as tipping points. Multiple tipping points affect each other’s probability of occurrence, potentially causing a `domino effect’. We analyse climate policy in the presence of a potential domino effect. We incorporate three different tipping points occurring at unknown thresholds into an integrated climate-economy model. The optimal emission policy considers all possible thresholds and the resulting interactions between tipping points, economic activity, and policy responses into the indefinite future. We quantify the cost of delaying optimal emission controls in the presence of uncertain tipping points and also the benefit of detecting when individual tipping points have been triggered. We show that the presence of these tipping points nearly doubles today’s optimal carbon tax and reduces peak warming along the optimal path by approximately 1 °C. The presence of these tipping points increases the cost of delaying optimal policy until mid-century by nearly 150%.

  20. Nanobits - exchangable and customisable scanning probe tips

    DEFF Research Database (Denmark)

    Yildiz, Izzet

    Invention of atomic force microscopy (AFM) pioneered a novel aspect for the surface metrology concept. A range of scanning probe methods have been developed over the years based on different sorts of tip-surface interaction: electrical, optical, thermal, force. Reproducible and fast fabrication...... miniaturisation requires the scanning probes to adapt into finer geometries to provide higher lateral resolution. To meet these needs critical dimension AFM (CD-AFM) and deep trench AFM (DT-AFM) were invented, which use different types of AFM tips: high-aspect-ratio tips for DT-AFM and CD tips for CD...... replacement could greatly increase the efficiency and adaptability of a CD system. In this PhD study, NanoBits – nano-sized customisable and exchangeable scanning probe tips – were developed to meet the demands of current AFM applications. Two different methods were followed for the fabrication of Nano...

  1. Soft Costs Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-05-01

    This fact sheet is an overview of the systems integration subprogram at the U.S. Department of Energy SunShot Initiative. Soft costs can vary significantly as a result of a fragmented energy marketplace. In the U.S., there are 18,000 jurisdictions and 3,000 utilities with different rules and regulations for how to go solar. The same solar equipment may vary widely in its final installation price due to process and market variations across jurisdictions, creating barriers to rapid industry growth. SunShot supports the development of innovative solutions that enable communities to build their local economies and establish clean energy initiatives that meet their needs, while at the same time creating sustainable solar market conditions.

  2. Systems Integration Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    This fact sheet is an overview of the Systems Integration subprogram at the U.S. Department of Energy SunShot Initiative. The Systems Integration subprogram enables the widespread deployment of safe, reliable, and cost-effective solar energy technologies by addressing the associated technical and non-technical challenges. These include timely and cost-effective interconnection procedures, optimal system planning, accurate prediction of solar resources, monitoring and control of solar power, maintaining grid reliability and stability, and many more. To address the challenges associated with interconnecting and integrating hundreds of gigawatts of solar power onto the electricity grid, the Systems Integration program funds research, development, and demonstration projects in four broad, interrelated focus areas: grid performance and reliability, dispatchability, power electronics, and communications.

  3. Photovoltaics Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-02-01

    This fact sheet is an overview of the Photovoltaics (PV) subprogram at the U.S. Department of Energy SunShot Initiative. The U.S. Department of Energy (DOE)’s Solar Energy Technologies Office works with industry, academia, national laboratories, and other government agencies to advance solar PV, which is the direct conversion of sunlight into electricity by a semiconductor, in support of the goals of the SunShot Initiative. SunShot supports research and development to aggressively advance PV technology by improving efficiency and reliability and lowering manufacturing costs. SunShot’s PV portfolio spans work from early-stage solar cell research through technology commercialization, including work on materials, processes, and device structure and characterization techniques.

  4. Material Safety Data Sheets (MSDS)

    CERN Document Server

    Lalley, J

    About 250.000 Material Safety Data sheets from the U.S. Government Department of Defense MSDS database, a mirror of data from siri.uvm.edu, MSDS sheets maintained by Cornell University Environmental Health and Safety and other Cornell departments.

  5. The tipping point: A mathematical model for the profit-driven abandonment of restaurant tipping

    Science.gov (United States)

    Clifton, Sara M.; Herbers, Eileen; Chen, Jack; Abrams, Daniel M.

    2018-02-01

    The custom of voluntarily tipping for services rendered has gone in and out of fashion in America since its introduction in the 19th century. Restaurant owners that ban tipping in their establishments often claim that social justice drives their decisions, but we show that rational profit-maximization may also justify the decisions. Here, we propose a conceptual model of restaurant competition for staff and customers, and we show that there exists a critical conventional tip rate at which restaurant owners should eliminate tipping to maximize profits. Because the conventional tip rate has been increasing steadily for the last several decades, our model suggests that restaurant owners may abandon tipping en masse when that critical tip rate is reached.

  6. Plasma dynamics in current sheets

    International Nuclear Information System (INIS)

    Bogdanov, S.Yu.; Drejden, G.V.; Kirij, N.P.; AN SSSR, Leningrad

    1992-01-01

    Plasma dynamics in successive stages of current sheet evolution is investigated on the base of analysis of time-spatial variations of electron density and electrodynamic force fields. Current sheet formation is realized in a two-dimensional magnetic field with zero line under the action of relatively small initial disturbances (linear regimes). It is established that in the limits of the formed sheet is concentrated dense (N e ∼= 10 16 cm -3 ) (T i ≥ 100 eV, bar-Z i ≥ 2) hot pressure of which is balanced by the magnetic action of electrodynamic forces is carried out both plasma compression in the sheet limits and the acceleration along the sheet surface from a middle to narrow side edges

  7. Micropropagation of Plantago asiatica L. through culture of shoot-tips

    Directory of Open Access Journals (Sweden)

    Joanna Makowczyńska

    2011-01-01

    Full Text Available Shoot-tip multiplication of the medicinal species - Plantago asiatica was carried on MS medium with IAA and BAP or kinetin. Best results in micropropagation were achieved by adding 0.1 mg/dm3 IAA and 1 mg/dm3 BAP. After 6 weeks shoots were transferred to MS medium for rooting. The resulting plantlets were transferred after 8 weeks into pots and after a period of adaptation into the ground (field culture. The species Plantago asiatica was propagated in vitro by shoot-tip multiplication for the first time.

  8. Crack Tip Mechanics in Distortion Gradient Plasticity

    DEFF Research Database (Denmark)

    Fuentes-Alonso, Sandra; Martínez Pañeda, Emilio

    2017-01-01

    The important role of geometrically necessary dislocations in structural integrity assessment has encouraged an extensive use of strain gradient plasticity theories to characterize the behavior at the small scales involved in crack tip deformation. However, despite the popularity of Distortion...... Gradient Plasticity (DGP), the influence on crack tip mechanics of DGP's distinguishing features that entail superior modelling capabilities has not been investigated yet. In this work crack tip fields are thoroughly examined by implementing the higher order theory of DGP in an implicit finite element...

  9. Rapid fabrication system for three-dimensional tissues using cell sheet engineering and centrifugation.

    Science.gov (United States)

    Hasegawa, Akiyuki; Haraguchi, Yuji; Shimizu, Tatsuya; Okano, Teruo

    2015-12-01

    Three-dimensional (3D) tissues can be reconstructed by cell sheet technology, and various clinical researches using these constructed tissues have already been initiated to regenerate damaged tissues. While 3D tissues can be easily fabricated by layering cell sheets, the attachment period for cell adhesion between a cell sheet and a culture dish, or double-layered cell sheets normally takes 20-30 min. This study proposed a more rapid fabrication system for bioengineered tissue using cell sheet technology and centrifugation. A C2C12 mouse myoblast sheet harvested from a temperature-responsive culture dish will attach tightly to a culture dish or another cell sheet at 37°C after a 20 min-incubation. However, the same cell sheet centrifuged (12-34 × g) for 3 min also attached tightly to a dish or another cell sheet at 37°C after only a 3 min-incubation. The manipulation time was reduced by approximately two-thirds by centrifugation. The rapid attachments were also cross-sectionally confirmed by optical coherence tomography. These rapidly constructed cell sheet-tissues using centrifugation showed active cell metabolism, cell viability, and very high production of vascular endothelial growth factor, like those prepared by the conventional method; indicating complete cell sheet-attachment without any cell damage. This new system will be a powerful tool in the fields of cell sheet-based tissue engineering and regenerative medicine, and accelerate the use of cell sheets in clinical applications. © 2015 Wiley Periodicals, Inc.

  10. Modelling the Antarctic Ice Sheet

    DEFF Research Database (Denmark)

    Pedersen, Jens Olaf Pepke; Holm, A.

    2015-01-01

    Science) Antarctic Ice Sheet (DAIS) model (Shaffer 2014) is forced by reconstructed time series of Antarctic temperature, global sea level and ocean subsurface temperature over the last two glacial cycles. In this talk a modelling work of the Antarctic ice sheet over most of the Cenozoic era using...... the DAIS model will be presented. G. Shaffer (2014) Formulation, calibration and validation of the DAIS model (version 1), a simple Antarctic ice sheet model sensitive to variations of sea level and ocean subsurface temperature, Geosci. Model Dev., 7, 1803‐1818...

  11. Smooth School Transitions: Tips for Military Families

    Science.gov (United States)

    ... Life Listen Text Size Email Print Share Smooth School Transitions: Tips for Military Families Page Content Article ... Internet is a great resource for this. District & School Web sites Parents and children can visit the ...

  12. Helping Your Child: Tips for Parents

    Science.gov (United States)

    ... inactive computer and video games, or listening to music on hand-held devices while sitting down. Tips ... habits or weight. Remember, you play the biggest role in your children's lives. You can help your ...

  13. Tips for Teens with Diabetes: About Diabetes

    Science.gov (United States)

    National Diabetes Education Program (NDEP), 2010

    2010-01-01

    Diabetes is a serious disease. It means that one's blood glucose, also called blood sugar, is too high. Having too much glucose in a person's blood is not healthy. This paper offers tips for managing diabetes.

  14. Winter Safety Tips for Older Adults

    Science.gov (United States)

    Winter Safety Tips for Older Adults Expert Information from Healthcare Professionals Who Specialize in the Care of ... thick clothing. Think about getting your thermals! –Essential winter wears: hats, gloves or preferably mittens, winter coat, ...

  15. Essential Outdoor Sun Safety Tips for Winter

    Science.gov (United States)

    ... Vitamin D Essential Outdoor Sun Safety Tips for Winter Winter sports enthusiasts are at increased risk for overexposure ... associated with sun exposure. "It's easy to associate winter with frostbite and windburn, but most people are ...

  16. Can't sleep? Try these tips

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000853.htm Can't sleep? Try these tips To use the sharing features ... time. But if it happens often, lack of sleep can affect your health and make it hard ...

  17. Sleep Tips: 7 Steps to Better Sleep

    Science.gov (United States)

    ... turn every night. Consider simple tips for better sleep, from setting a sleep schedule to including physical activity in your daily ... factors that can interfere with a good night's sleep — from work stress and family responsibilities to unexpected ...

  18. Impetigo: Tips for Treatment and Prevention

    Science.gov (United States)

    ... DO Videos Contact Close ‹ Back to Healthy Living Impetigo: Tips for Treatment and Prevention The symptoms of ... to other parts of their bodies. Causes of Impetigo Impetigo usually affects preschool and school-aged children, ...

  19. Next Stop Adulthood: Tips for Parents

    Science.gov (United States)

    ... Email Print Share Next Stop Adulthood: Tips For Parents Page Content Article Body Becoming a young adult is exciting, difficult, and scary for both parents and teens. It is a time of increasing ...

  20. 6 Tips: IBS and Complementary Health Practices

    Science.gov (United States)

    ... health practice for IBS, here are 6 tips: Hypnotherapy (hypnosis). This practice involves the power of suggestion by ... IBS. According to reviews of the scientific literature, hypnotherapy may be a helpful treatment for managing IBS ...

  1. Tips to Manage Anxiety and Stress

    Science.gov (United States)

    ... 2018 Conference Snapshot Tips to Manage Anxiety and Stress When you're feeling anxious or stressed, the ... Subscribe to ADAA Triumph: Free Monthly E-News Stress Relief Kits Feeling stressed? Get an ADAA stress ...

  2. Tip velocity tracking control for elastic manipulators

    Science.gov (United States)

    Sever, Manfred Dieter Martin

    A unique approach to tip velocity control of an elastic robotic manipulator is presented. This method has potential application in teleoperation control and in applications where the trajectory is generated in real-time. Control is effected by reducing the tip velocity tracking error between the desired tip velocity and the measured tip velocity. Thus, in teleoperation, the concept of dead reckoning is used, so that while the manipulator's desired tip velocity is specified, the goal is for the tip to follow a path, leading toward a desired terminal position. This is done by concentrating the controller's effort on the manipulator tip while allowing the manipulator's links to deform., The controller utilizes a gain scheduling scheme to arrive at an appropriate feedback law. The control algorithm is implemented using a parallel-processing scheme on a multiprocessor system which consists of INMOS TransputersRTM . Experimental results are obtained using Radius, the Space Robotics Laboratory Facility at the University of Toronto Institute for Aerospace Studies. Radius was designed to serve specifically as a test-bed for the development and evaluation of control methods for elastic manipulators. For the present work Radius is configured as a two-link manipulator with both links structurally flexible. One of the trajectories used for the simulations and experiment is a square, which is quite difficult for an elastic manipulator to execute. This box trajectory is more demanding than trajectories typically executed by Canadarm and so link elasticity becomes an important consideration. The effect of elasticity is demonstrated using an independent joint PD controller. In simulation, excellent tip velocity tracking was achieved using the proposed controller. In the experiment, reasonable accuracy in following the desired tip path was attained, however, disturbances, mainly a result of unmodeled joint dynamics, caused degraded performance. The controller may be improved by

  3. Stress induced martensite at the crack tip in NiTi alloys during fatigue loading

    Directory of Open Access Journals (Sweden)

    E. Sgambitterra

    2014-10-01

    Full Text Available Crack tip stress-induced phase transformation mechanisms in nickel-titanium alloys (NiTi were analyzed by Digital Image Correlation (DIC, under fatigue loads. In particular, Single Edge Crack (SEC specimens, obtained from a commercial pseudoelastic NiTi sheet, and an ad-hoc experimental setup were used, for direct measurements of the near crack tip displacement field by the DIC technique. Furthermore, a fitting procedure was developed to calculate the mode I Stress Intensity Factor (SIF, starting from the measured displacement field. Finally, cyclic tensile tests were performed at different operating temperature, in the range 298-338 K, and the evolution of the SIF was studied, which revealed a marked temperature dependence.

  4. Turn Motors Off When Not in Use - Motor Tip Sheet #10

    Energy Technology Data Exchange (ETDEWEB)

    None

    2008-07-01

    Motors use no energy when turned off. Reducing motor operating time by just 10% usually saves more energy than replacing a standard efficiency motor with a NEMA Premium® efficiency motor. In fact, given that 97% of the life cycle cost of purchasing and operating a motor is energy-related, turning a motor off 10% of the time could reduce energy costs enough to purchase three new motors.

  5. Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.

    Directory of Open Access Journals (Sweden)

    Katie Bentley

    2009-10-01

    Full Text Available Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF. Tip cells meet and fuse (anastomosis to form blood-flow supporting loops. Tip cell selection is achieved by Dll4-Notch mediated lateral inhibition resulting, under normal conditions, in an interleaved arrangement of tip and non-migrating stalk cells. Previously, we showed that the increased VEGF levels found in many diseases can cause the delayed negative feedback of lateral inhibition to produce abnormal oscillations of tip/stalk cell fates. Here we describe the development and implementation of a novel physics-based hierarchical agent model, tightly coupled to in vivo data, to explore the system dynamics as perpetual lateral inhibition combines with tip cell migration and fusion. We explore the tipping point between normal and abnormal sprouting as VEGF increases. A novel filopodia-adhesion driven migration mechanism is presented and validated against in vivo data. Due to the unique feature of ongoing lateral inhibition, 'stabilised' tip/stalk cell patterns show sensitivity to the formation of new cell-cell junctions during fusion: we predict cell fates can reverse. The fusing tip cells become inhibited and neighbouring stalk cells flip fate, recursively providing new tip cells. Junction size emerges as a key factor in establishing a stable tip/stalk pattern. Cell-cell junctions elongate as tip cells migrate, which is shown to provide positive feedback to lateral inhibition, causing it to be more susceptible to pathological oscillations. Importantly, down-regulation of the migratory pathway alone is shown to be sufficient to rescue the sprouting system from oscillation and restore stability. Thus we suggest the use of migration inhibitors as therapeutic agents for vascular

  6. 2007 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  7. 2006 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  8. 2009 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  9. 2008 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  10. 2010 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  11. 2012 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  12. State Fact Sheets on COPD

    Science.gov (United States)

    ... Submit Search The CDC Chronic Obstructive Pulmonary Disease (COPD) Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . COPD Homepage Data and Statistics Fact Sheets Publications Publications ...

  13. Twelve tips for the effective use of videos in medical education.

    Science.gov (United States)

    Dong, Chaoyan; Goh, Poh Sun

    2015-02-01

    Videos can promote learning by either complementing classroom activities, or in self-paced online learning modules. Despite the wide availability of online videos in medicine, it can be a challenge for many educators to decide when videos should be used, how to best use videos, and whether to use existing videos or produce their own. We outline 12 tips based on a review of best practices in curriculum design, current research in multimedia learning and our experience in producing and using educational videos. The 12 tips review the advantages of using videos in medical education, present requirements for teachers and students, discuss how to integrate video into a teaching programme, and describe technical requirements when producing one's own videos. The 12 tips can help medical educators use videos more effectively to promote student engagement and learning.

  14. The future of ice sheets and sea ice: between reversible retreat and unstoppable loss.

    Science.gov (United States)

    Notz, Dirk

    2009-12-08

    We discuss the existence of cryospheric "tipping points" in the Earth's climate system. Such critical thresholds have been suggested to exist for the disappearance of Arctic sea ice and the retreat of ice sheets: Once these ice masses have shrunk below an anticipated critical extent, the ice-albedo feedback might lead to the irreversible and unstoppable loss of the remaining ice. We here give an overview of our current understanding of such threshold behavior. By using conceptual arguments, we review the recent findings that such a tipping point probably does not exist for the loss of Arctic summer sea ice. Hence, in a cooler climate, sea ice could recover rapidly from the loss it has experienced in recent years. In addition, we discuss why this recent rapid retreat of Arctic summer sea ice might largely be a consequence of a slow shift in ice-thickness distribution, which will lead to strongly increased year-to-year variability of the Arctic summer sea-ice extent. This variability will render seasonal forecasts of the Arctic summer sea-ice extent increasingly difficult. We also discuss why, in contrast to Arctic summer sea ice, a tipping point is more likely to exist for the loss of the Greenland ice sheet and the West Antarctic ice sheet.

  15. Full tip imaging in atom probe tomography

    Energy Technology Data Exchange (ETDEWEB)

    Du, Sichao [School of Physics, The University of Sydney, NSW 2006 (Australia); Burgess, Timothy [Department of Electronic Materials Engineering, Research School of Physics and Engineering, The Australian National University, Canberra, ACT 0200 (Australia); Tjing Loi, Shyeh [Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW 2006 (Australia); Gault, Baptiste [Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW 2006 (Australia); School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, NSW 2006 (Australia); Department of Materials Science and Engineering, McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4L8 (Canada); Gao, Qiang [Department of Electronic Materials Engineering, Research School of Physics and Engineering, The Australian National University, Canberra, ACT 0200 (Australia); Bao, Peite; Li, Li [School of Physics, The University of Sydney, NSW 2006 (Australia); Cui, Xiangyuan; Kong Yeoh, Wai [Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW 2006 (Australia); Hoe Tan, Hark; Jagadish, Chennupati [Department of Electronic Materials Engineering, Research School of Physics and Engineering, The Australian National University, Canberra, ACT 0200 (Australia); Ringer, Simon P. [Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW 2006 (Australia); School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, NSW 2006 (Australia); Zheng, Rongkun, E-mail: rongkun.zheng@sydney.edu.au [School of Physics, The University of Sydney, NSW 2006 (Australia)

    2013-01-15

    Atom probe tomography (APT) is capable of simultaneously revealing the chemical identities and three dimensional positions of individual atoms within a needle-shaped specimen, but suffers from a limited field-of-view (FOV), i.e., only the core of the specimen is effectively detected. Therefore, the capacity to analyze the full tip is crucial and much desired in cases that the shell of the specimen is also the region of interest. In this paper, we demonstrate that, in the analysis of III-V nanowires epitaxially grown from a substrate, the presence of the flat substrate positioned only micrometers away from the analyzed tip apex alters the field distribution and ion trajectories, which provides extra image compression that allows for the analysis of the entire specimen. An array of experimental results, including field desorption maps, elemental distributions, and crystallographic features clearly demonstrate the fact that the whole tip has been imaged, which is confirmed by electrostatic simulations. -- Highlights: Black-Right-Pointing-Pointer The full tip has been imaged by atom probe tomography. Black-Right-Pointing-Pointer The conductive substrate close to specimen tip introduces extra image compression. Black-Right-Pointing-Pointer The apex of the tip is far from a hemispherical shape. Black-Right-Pointing-Pointer This work demonstrates a way to increase the FOV of APT.

  16. Energy information sheets, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  17. Energy information sheets, September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  18. Aerospace Medicine

    Science.gov (United States)

    Michaud, Vince

    2015-01-01

    NASA Aerospace Medicine overview - Aerospace Medicine is that specialty area of medicine concerned with the determination and maintenance of the health, safety, and performance of those who fly in the air or in space.

  19. Nuclear Medicine.

    Science.gov (United States)

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  20. Technical tips to enhance micrografting results in burn surgery.

    Science.gov (United States)

    Chong, Si Jack; Choke, Abby; Tan, Bien-Keem

    2017-08-01

    The lack of autograft donor site is one of the greatest limiting factors for the treatment of extensive burn. Micrografting is an important revolution in burn surgery where autografts are cut into small pieces for wide and rapid coverage of burn wound. Our early experiences with the current standard micrografting technique were fraught with poor graft take as well being time and labor intensive. We have improvised our technique, where we combined the use of allograft to serve as a carrier for the micrograft. The objective of this paper is to share our experience in micrografting and several technical tips which had enhanced our micrografting results. The improvisation in our technique includes: (1) Single-stage 'micrograft-allograft sandwich method' where allograft served as a direct carrier for the micrografts. Micrografts were laid uniformly 1cm apart onto allograft sheets, creating a 1:9 expansion ratio. This technique replaced the original two stage method. (2) The use of the Meek device (Humeca, Netherlands) to prepare micrograft. The Meek device can rapidly produce 3mm micrografts for easy transfer with a fine forceps. (3) The use of slow-acting fibrin sealant to promote graft take and hemostasis. (4) A two-team approach for micrograft preparation where one team processes micrograft and another prepares the allograft sheets. This reduces the lag time between micrograft preparation and grafting, and reduces the overall surgery time. Micrografting remains an important treatment for major burn surgery. The aim of micro-allograft combination is to allow autografts re-epithelization under a reliable temporary skin coverage in a single stage procedure. A prospective study is warranted to measure the objective outcome of this renewed technique. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

  1. Optical fiber tips for biological applications: From light confinement, biosensing to bioparticles manipulation.

    Science.gov (United States)

    Paiva, Joana S; Jorge, Pedro A S; Rosa, Carla C; Cunha, João P S

    2018-05-01

    The tip of an optical fiber has been considered an attractive platform in Biology. The simple cleaved end of an optical fiber can be machined, patterned and/or functionalized, acquiring unique properties enabling the exploitation of novel optical phenomena. Prompted by the constant need to measure and manipulate nanoparticles, the invention of the Scanning Near-field Optical Microscopy (SNOM) triggered the optimization and development of novel fiber tip microfabrication methods. In fact, the fiber tip was soon considered a key element in SNOM by confining light to sufficiently small extensions, challenging the diffraction limit. As result and in consequence of the newly proposed "Lab On Tip" concept, several geometries of fiber tips were applied in three main fields: imaging (in Microscopy/Spectroscopy), biosensors and micromanipulation (Optical Fiber Tweezers, OFTs). These are able to exert forces on microparticles, trap and manipulate them for relevant applications, as biomolecules mechanical study or protein aggregates unfolding. This review presents an overview of the main achievements, most impactful studies and limitations of fiber tip-based configurations within the above three fields, along the past 10 years. OFTs could be in future a valuable tool for studying several cellular phenomena such as neurodegeneration caused by abnormal protein fibrils or manipulating organelles within cells. This could contribute to understand the mechanisms of some diseases or biophenomena, as the axonal growth in neurons. To the best of our knowledge, no other review article has so far provided such a broad view. Despite of the limitations, fiber tips have key roles in Biology/Medicine. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Cryopreservation of Thymus cariensis and T. vulgaris shoot tips: comparison of three vitrification-based methods.

    Science.gov (United States)

    Ozudogru, E A; Kaya, E

    2012-01-01

    Thymus is an important genus of the Lamiaceae family, comprising more than 400 perennial aromatic thyme species, which are used extensively for medicinal and culinary purposes. The present study focused on the development of cryopreservation procedures for Thymus vulgaris and T. cariensis, the latter being an endemic and endangered species of Turkey. For cryopreservation of T. vulgaris shoot tips, PVS2-based one-step freezing methods, i.e., PVS2 vitrification, encapsulation-vitrification and droplet-vitrification, were compared. Cold hardening and sucrose preculture were also optimized before the cryopreservation trials. For T. cariensis, a droplet-vitrification method was applied to cold-hardened shoot tips, and after sucrose preculture. In all the methods tested, PVS2 was applied for up to 120 min. The best T. vulgaris cryopreservation was achieved with a droplet-vitrification method, that involved 2-weeks cold hardening of shoot cultures, 48 h preculture of shoot tips on MS medium supplemented with 0.25 M sucrose, and a 90 min PVS2 treatment in droplets. After direct immersion in LN, thawing and plating, 80% of shoot-tips recovered. Post-thaw recovery was significantly lower when the same procedure was applied to T. cariensis shoot tips; however also here 90 min PVS2 treatment produced the highest survival (25 percent) and recovery (25 percent) levels.

  3. Antilock Braking Systems: Traffic Safety Tips

    Science.gov (United States)

    1996-01-01

    This fact sheet, the NHTSA Facts: Summer 1996, defines antilock braking systems, and discusses their benefits, how they work, and their major components. It also details how one would get used to antilock brakes, discussing how they feel and operate ...

  4. 78 FR 13402 - Proposed Collection; Comment Request for Tip Reporting Alternative Tip Agreement Used in the...

    Science.gov (United States)

    2013-02-27

    ... Used in the Cosmetology and Barber Industry AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning tip reporting alternative commitment used in the cosmetology...: Tip Reporting Alternative Commitment Agreement used in the Cosmetology and Barber Industry. OMB Number...

  5. 75 FR 11226 - Proposed Collection; Comment Request for Tip Reporting Alternative Tip Agreement Used in the...

    Science.gov (United States)

    2010-03-10

    ... Used in the Cosmetology and Barber Industry AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning Tip Reporting Alternative Commitment used in the Cosmetology...: Tip Reporting Alternative Commitment Agreement used in the Cosmetology and Barber Industry. OMB Number...

  6. Automobile sheet metal part production with incremental sheet forming

    Directory of Open Access Journals (Sweden)

    İsmail DURGUN

    2016-02-01

    Full Text Available Nowadays, effect of global warming is increasing drastically so it leads to increased interest on energy efficiency and sustainable production methods. As a result of adverse conditions, national and international project platforms, OEMs (Original Equipment Manufacturers, SMEs (Small and Mid-size Manufacturers perform many studies or improve existing methodologies in scope of advanced manufacturing techniques. In this study, advanced manufacturing and sustainable production method "Incremental Sheet Metal Forming (ISF" was used for sheet metal forming process. A vehicle fender was manufactured with or without die by using different toolpath strategies and die sets. At the end of the study, Results have been investigated under the influence of method and parameters used.Keywords: Template incremental sheet metal, Metal forming

  7. Horizontal electromagnetic casting of thin metal sheets

    Science.gov (United States)

    Hull, John R.; Lari, Robert J.; Praeg, Walter F.; Turner, Larry R.

    1987-01-01

    Thin metal sheets are cast by magnetically suspending molten metal deposited within a ferromagnetic yoke and between AC conducting coils and linearly displacing the magnetically levitated liquid metal while it is being cooled to form a solid metal sheet. Magnetic flux increases as the molten metal sheet moves downward and decreases as the molten metal sheet moves upward to stabilize the sheet and maintain it in equilibrium as it is linearly displaced and solidified by cooling gases. A conducting shield is electrically coupled to the molten metal sheet by means of either metal sheet engaging rollers or brushes on the solidified metal, and by means of an electrode in the vessel containing the molten metal thereby providing a return path for the eddy currents induced in the metal sheet by the AC coil generated magnetic flux. Variation in the geometry of the conducting shield allows the magnetic flux between the metal sheet and the conducting shield to be varied and the thickness in surface quality of the metal sheet to be controlled. Side guards provide lateral containment for the molten metal sheet and stabilize and shape the magnetic field while a leader sheet having electromagnetic characteristics similar to those of the metal sheet is used to start the casting process and precedes the molten metal sheet through the magnet and forms a continuous sheet therewith. The magnet may be either U-shaped with a single racetrack coil or may be rectangular with a pair of facing bedstead coils.

  8. Horizontal electromagnetic casting of thin metal sheets

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL); Lari, Robert J. (Aurora, IL); Praeg, Walter F. (Palos Park, IL); Turner, Larry R. (Naperville, IL)

    1988-01-01

    Thin metal sheets are cast by magnetically suspending molten metal deposited within a ferromagnetic yoke and between AC conducting coils and linearly displacing the magnetically levitated liquid metal while it is being cooled to form a solid metal sheet. Magnetic flux increases as the molten metal sheet moves downward and decreases as the molten metal sheet moves upward to stabilize the sheet and maintain it in equilibrium as it is linearly displaced and solidified by cooling gases. A conducting shield is electrically coupled to the molten metal sheet by means of either metal sheet engaging rollers or brushes on the solidified metal, and by means of an electrode in the vessel containing the molten metal thereby providing a return path for the eddy currents induced in the metal sheet by the AC coil generated magnetic flux. Variation in the geometry of the conducting shield allows the magnetic flux between the metal sheet and the conducting shield to be varied and the thickness in surface quality of the metal sheet to be controlled. Side guards provide lateral containment for the molten metal sheet and stabilize and shape the magnetic field while a leader sheet having electromagnetic characteristics similar to those of the metal sheet is used to start the casting process and precedes the molten metal sheet through the magnet and forms a continuous sheet therewith. The magnet may be either U-shaped with a single racetrack coil or may be rectangular with a pair of facing bedstead coils.

  9. Soldering sheets using soft solders

    Directory of Open Access Journals (Sweden)

    Milan Brožek

    2013-01-01

    Full Text Available The paper contains strength tests results of joints soldered using lead and leadless soft solders. For tests lead solders types Pb60Sn40 and Sn60Pb40 and leadless soft solders types Sn95.5Ag3.8Cu0.7 and Sn96Ag4 were used. As basic materials steel sheet, zinc-coated steel sheet, copper sheet and brass sheet 100 x 20 x 1 mm was the test samples size. Always two sheets were cleaned and jointed together. For heating the propane-butane + air flame was used. Then the tested assemblies were loaded using the universal tensile-strength testing machine till to failure. At the tests the force needed for assemblies failure and failure type (in soldered joint, in basic material were recorded. From measured data the solder strength was calculated. From the experiment results it follows that from the point of view of the soldered joints strength as well of the solder strength relatively small differences were found. At the same time it is evident that the joint strength and solder strength depend on soldered material type and on soldered joint lapping length. On the basis of carried out experiments it can be stated that the substitution of lead solders by leadless solders is possible without risk of soldered joints strength decrease.

  10. Uranium mining sites - Thematic sheets

    International Nuclear Information System (INIS)

    2009-01-01

    A first sheet proposes comments, data and key numbers about uranium extraction in France: general overview of uranium mining sites, status of waste rock and tailings after exploitation, site rehabilitation. The second sheet addresses the sources of exposure to ionizing radiations due to ancient uranium mining sites: discussion on the identification of these sources associated with these sites, properly due to mining activities or to tailings, or due to the transfer of radioactive substances towards water and to the contamination of sediments, description of the practice and assessment of radiological control of mining sites. A third sheet addresses the radiological exposure of public to waste rocks, and the dose assessment according to exposure scenarios: main exposure ways to be considered, studied exposure scenarios (passage on backfilled path and grounds, stay in buildings built on waste rocks, keeping mineralogical samples at home). The fourth sheet addresses research programmes of the IRSN on uranium and radon: epidemiological studies (performed on mine workers; on French and on European cohorts, French and European studies on the risk of lung cancer associated with radon in housing), study of the biological effects of chronic exposures. The last sheet addresses studies and expertises performed by the IRSN on ancient uranium mining sites in France: studies commissioned by public authorities, radioactivity control studies performed by the IRSN about mining sites, participation of the IRSN to actions to promote openness to civil society

  11. Surface modification of polyimide sheets for regenerative medicine applications

    Czech Academy of Sciences Publication Activity Database

    van Vlierberghe, S.; Šírová, Milada; Rossmann, Pavel; Thielecke, H.; Boterberg, V.; Říhová, Blanka; Schacht, E.; Dubruel, P.

    2010-01-01

    Roč. 11, č. 10 (2010), s. 2731-2739 ISSN 1525-7797 Institutional research plan: CEZ:AV0Z50200510 Keywords : NEURAL IMPLANT * POLYMER-FILMS * BIOCOMPATIBILITY Subject RIV: CE - Biochemistry Impact factor: 5.327, year: 2010

  12. Nuclear medicine

    International Nuclear Information System (INIS)

    Lentle, B.C.

    1986-01-01

    Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments

  13. Tip vortices in the actuator line model

    Science.gov (United States)

    Martinez, Luis; Meneveau, Charles

    2017-11-01

    The actuator line model (ALM) is a widely used tool to represent the wind turbine blades in computational fluid dynamics without the need to resolve the full geometry of the blades. The ALM can be optimized to represent the `correct' aerodynamics of the blades by choosing an appropriate smearing length scale ɛ. This appropriate length scale creates a tip vortex which induces a downwash near the tip of the blade. A theoretical frame-work is used to establish a solution to the induced velocity created by a tip vortex as a function of the smearing length scale ɛ. A correction is presented which allows the use of a non-optimal smearing length scale but still provides the downwash which would be induced using the optimal length scale. Thanks to the National Science Foundation (NSF) who provided financial support for this research via Grants IGERT 0801471, IIA-1243482 (the WINDINSPIRE project) and ECCS-1230788.

  14. Heart failure - medicines

    Science.gov (United States)

    CHF - medicines; Congestive heart failure - medicines; Cardiomyopathy - medicines; HF - medicines ... will need to take most of your heart failure medicines every day. Some medicines are taken once ...

  15. SPR Characteristics Curve and Distribution of Residual Stress in Self-Piercing Riveted Joints of Steel Sheets

    Directory of Open Access Journals (Sweden)

    Rezwanul Haque

    2017-01-01

    Full Text Available Neutron diffraction was used to describe the residual stress distributions in self-piercing riveted (SPR joints. The sheet material displayed a compressive residual stress near the joint, and the stress gradually became tensile in the sheet material far away from the joint. The stress in the rivet leg was lower in the thick joint of the softer steel sheet than in the thin joint of the harder steel sheet. This lower magnitude was attributed to the lower force gradient during the rivet flaring stage of the SPR process curve. This study shows how the residual stress results may be related to the physical occurrences that happened during joining, using the characteristics curve. The study also shows that neutron diffraction technique enabled a crack in the rivet tip to be detected which was not apparent from a cross-section.

  16. Non-dissipative shapable sheet

    Science.gov (United States)

    Oppenheimer, Naomi; Witten, Thomas

    2014-03-01

    A sheet of paper that has been crumpled and flattened retains some amount of shapability that a bare, uncrumpled, sheet does not have: when deformed by external forces, it retains the deformed shape after the forces are removed. Using a frustrated two dimensional lattice of springs, we show that such shapability can be attained in a non-dissipative system. Numerical investigations suggest an extensive number of bistable energy minima using several variants of this scheme. The numerical sheet can be bent into a nearly-closed cylinder that holds its shape. We verify that the deformed shape is locally stable and compare its bending modulus in the deformed state with that in the initial flat state. We investigate the threshold for non-elastic deformation using various kinds of forcing.

  17. Root-growth-inhibiting sheet

    Science.gov (United States)

    Burton, Frederick G.; Cataldo, Dominic A.; Cline, John F.; Skiens, W. Eugene; Van Voris, Peter

    1993-01-01

    In accordance with this invention, a porous sheet material is provided at intervals with bodies of a polymer which contain a 2,6-dinitroaniline. The sheet material is made porous to permit free passage of water. It may be either a perforated sheet or a woven or non-woven textile material. A particularly desirable embodiment is a non-woven fabric of non-biodegradable material. This type of material is known as a "geotextile" and is used for weed control, prevention of erosion on slopes, and other landscaping purposes. In order to obtain a root repelling property, a dinitroaniline is blended with a polymer which is attached to the geotextile or other porous material.

  18. Sheet Bending using Soft Tools

    Science.gov (United States)

    Sinke, J.

    2011-05-01

    Sheet bending is usually performed by air bending and V-die bending processes. Both processes apply rigid tools. These solid tools facilitate the generation of software for the numerical control of those processes. When the lower rigid die is replaced with a soft or rubber tool, the numerical control becomes much more difficult, since the soft tool deforms too. Compared to other bending processes the rubber backed bending process has some distinct advantages, like large radius-to-thickness ratios, applicability to materials with topcoats, well defined radii, and the feasibility of forming details (ridges, beads). These advantages may give the process exclusive benefits over conventional bending processes, not only for industries related to mechanical engineering and sheet metal forming, but also for other disciplines like Architecture and Industrial Design The largest disadvantage is that also the soft (rubber) tool deforms. Although the tool deformation is elastic and recovers after each process cycle, the applied force during bending is related to the deformation of the metal sheet and the deformation of the rubber. The deformation of the rubber interacts with the process but also with sheet parameters. This makes the numerical control of the process much more complicated. This paper presents a model for the bending of sheet materials using a rubber lower die. This model can be implemented in software in order to control the bending process numerically. The model itself is based on numerical and experimental research. In this research a number of variables related to the tooling and the material have been evaluated. The numerical part of the research was used to investigate the influence of the features of the soft lower tool, like the hardness and dimensions, and the influence of the sheet thickness, which also interacts with the soft tool deformation. The experimental research was focused on the relation between the machine control parameters and the most

  19. Cell sheet-based tissue engineering for fabricating 3-dimensional heart tissues.

    Science.gov (United States)

    Shimizu, Tatsuya

    2014-01-01

    In addition to stem cell biology, tissue engineering is an essential research field for regenerative medicine. In contrast to cell injection, bioengineered tissue transplantation minimizes cell loss and has the potential to repair tissue defects. A popular approach is scaffold-based tissue engineering, which utilizes a biodegradable polymer scaffold for seeding cells; however, new techniques of cell sheet-based tissue engineering have been developed. Cell sheets are harvested from temperature-responsive culture dishes by simply lowering the temperature. Monolayer or stacked cell sheets are transplantable directly onto damaged tissues and cell sheet transplantation has already been clinically applied. Cardiac cell sheet stacking produces pulsatile heart tissue; however, lack of vasculature limits the viable tissue thickness to 3 layers. Multistep transplantation of triple-layer cardiac cell sheets cocultured with endothelial cells has been used to form thick vascularized cardiac tissue in vivo. Furthermore, in vitro functional blood vessel formation within 3-dimensional (3D) tissues has been realized by successfully imitating in vivo conditions. Triple-layer cardiac cell sheets containing endothelial cells were layered on vascular beds and the constructs were media-perfused using novel bioreactor systems. Interestingly, cocultured endothelial cells migrate into the vascular beds and form perfusable blood vessels. An in vitro multistep procedure has also enabled the fabrication of thick, vascularized heart tissues. Cell sheet-based tissue engineering has revealed great potential to fabricate 3D cardiac tissues and should contribute to future treatment of severe heart diseases and human tissue model production.

  20. Tip-Based Nanofabrication for Scalable Manufacturing

    Directory of Open Access Journals (Sweden)

    Huan Hu

    2017-03-01

    Full Text Available Tip-based nanofabrication (TBN is a family of emerging nanofabrication techniques that use a nanometer scale tip to fabricate nanostructures. In this review, we first introduce the history of the TBN and the technology development. We then briefly review various TBN techniques that use different physical or chemical mechanisms to fabricate features and discuss some of the state-of-the-art techniques. Subsequently, we focus on those TBN methods that have demonstrated potential to scale up the manufacturing throughput. Finally, we discuss several research directions that are essential for making TBN a scalable nano-manufacturing technology.

  1. Social tipping points and Earth systems dynamics

    Directory of Open Access Journals (Sweden)

    R. Alexander eBentley

    2014-08-01

    Full Text Available Recently, Early Warning Signals (EWS have been developed to predict tipping points in Earth Systems. This discussion highlights the potential to apply EWS to human social and economic systems, which may also undergo similar critical transitions. Social tipping points are particularly difficult to predict, however, and the current formulation of EWS, based on a physical system analogy, may be insufficient. As an alternative set of EWS for social systems, we join with other authors encouraging a focus on heterogeneity, connectivity through social networks and individual thresholds to change.

  2. Windows 7 Annoyances Tips, Secrets, and Solutions

    CERN Document Server

    Karp, David

    2010-01-01

    Windows 7 may be faster and more stable than Vista, but it's a far cry from problem-free. David A. Karp comes to the rescue with the latest in his popular Windows Annoyances series. This thorough guide gives you the tools you need to fix the troublesome parts of this operating system, plus the solutions, hacks, and timesaving tips to make the most of your PC. Streamline Windows Explorer, improve the Search tool, eliminate the Green Ribbon of Death, and tame User Account Control promptsExplore powerful Registry tips and tools, and use them to customize every aspect of Windows and solve its sho

  3. Ice sheet hydrology - a review

    International Nuclear Information System (INIS)

    Jansson, Peter; Naeslund, Jens-Ove; Rodhe, Lars

    2007-03-01

    This report summarizes the theoretical knowledge on water flow in and beneath glaciers and ice sheets and how these theories are applied in models to simulate the hydrology of ice sheets. The purpose is to present the state of knowledge and, perhaps more importantly, identify the gaps in our understanding of ice sheet hydrology. Many general concepts in hydrology and hydraulics are applicable to water flow in glaciers. However, the unique situation of having the liquid phase flowing in conduits of the solid phase of the same material, water, is not a commonly occurring phenomena. This situation means that the heat exchange between the phases and the resulting phase changes also have to be accounted for in the analysis. The fact that the solidus in the pressure-temperature dependent phase diagram of water has a negative slope provides further complications. Ice can thus melt or freeze from both temperature and pressure variations or variations in both. In order to provide details of the current understanding of water flow in conjunction with deforming ice and to provide understanding for the development of ideas and models, emphasis has been put on the mathematical treatments, which are reproduced in detail. Qualitative results corroborating theory or, perhaps more often, questioning the simplifications made in theory, are also given. The overarching problem with our knowledge of glacier hydrology is the gap between the local theories of processes and the general flow of water in glaciers and ice sheets. Water is often channelized in non-stationary conduits through the ice, features which due to their minute size relative to the size of glaciers and ice sheets are difficult to incorporate in spatially larger models. Since the dynamic response of ice sheets to global warming is becoming a key issue in, e.g. sea-level change studies, the problems of the coupling between the hydrology of an ice sheet and its dynamics is steadily gaining interest. New work is emerging

  4. Ice sheet hydrology - a review

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Peter; Naeslund, Jens-Ove [Dept. of Physical Geography and Quaternary Geology, Stockholm Univ., Stockholm (Sweden); Rodhe, Lars [Geological Survey of Sweden, Uppsala (Sweden)

    2007-03-15

    This report summarizes the theoretical knowledge on water flow in and beneath glaciers and ice sheets and how these theories are applied in models to simulate the hydrology of ice sheets. The purpose is to present the state of knowledge and, perhaps more importantly, identify the gaps in our understanding of ice sheet hydrology. Many general concepts in hydrology and hydraulics are applicable to water flow in glaciers. However, the unique situation of having the liquid phase flowing in conduits of the solid phase of the same material, water, is not a commonly occurring phenomena. This situation means that the heat exchange between the phases and the resulting phase changes also have to be accounted for in the analysis. The fact that the solidus in the pressure-temperature dependent phase diagram of water has a negative slope provides further complications. Ice can thus melt or freeze from both temperature and pressure variations or variations in both. In order to provide details of the current understanding of water flow in conjunction with deforming ice and to provide understanding for the development of ideas and models, emphasis has been put on the mathematical treatments, which are reproduced in detail. Qualitative results corroborating theory or, perhaps more often, questioning the simplifications made in theory, are also given. The overarching problem with our knowledge of glacier hydrology is the gap between the local theories of processes and the general flow of water in glaciers and ice sheets. Water is often channelized in non-stationary conduits through the ice, features which due to their minute size relative to the size of glaciers and ice sheets are difficult to incorporate in spatially larger models. Since the dynamic response of ice sheets to global warming is becoming a key issue in, e.g. sea-level change studies, the problems of the coupling between the hydrology of an ice sheet and its dynamics is steadily gaining interest. New work is emerging

  5. Sheet Beam Klystron Instability Analysis

    International Nuclear Information System (INIS)

    Bane, K.

    2009-01-01

    Using the principle of energy balance we develop a 2D theory for calculating growth rates of instability in a two-cavity model of a sheet beam klystron. An important ingredient is a TE-like mode in the gap that also gives a longitudinal kick to the beam. When compared with a self-consistent particle-in-cell calculation, with sheet beam klystron-type parameters, agreement is quite good up to half the design current, 65 A; at full current, however, other, current-dependent effects come in and the results deviate significantly

  6. Children in Hot Cars Result in Fatal Consequences

    Medline Plus

    Full Text Available ... Arrives What To Do In A Medical Emergency Childhood Emergencies Careers in Emergency Medicine Seconds Save Lives ... Care Fact Sheet Health & Safety Tips Campaigns SUBSCRIBE Health Tips Share this! Home » Health Tips » Holiday and ...

  7. Hydrogeological map of Kabo Sheet 80NW topographical sheet 1 ...

    African Journals Online (AJOL)

    A hydro geological mapping of the Federal Surveys of Nigeria, Kabo Sheet 80 NW, on scale 1:50,000 were made with areal coverage of 729Km2 on the Crystalline Basement Complex, and the hydrogeoogical maps produced are maps of depth to the water table and maps of configuration peak of dry season and wet ...

  8. Turbine blade squealer tip rail with fence members

    Science.gov (United States)

    Little, David A

    2012-11-20

    A turbine blade includes an airfoil, a blade tip section, a squealer tip rail, and a plurality of chordally spaced fence members. The blade tip section includes a blade tip floor located at an end of the airfoil distal from the root. The blade tip floor includes a pressure side and a suction side joined together at chordally spaced apart leading and trailing edges of the airfoil. The squealer tip rail extends radially outwardly from the blade tip floor adjacent to the suction side and extends from a first location adjacent to the airfoil trailing edge to a second location adjacent to the airfoil leading edge. The fence members are located between the airfoil leading and trailing edges and extend radially outwardly from the blade tip floor and axially from the squealer tip rail toward the pressure side.

  9. Dielectrophoretic positioning of single nanoparticles on atomic force microscope tips for tip-enhanced Raman spectroscopy.

    Science.gov (United States)

    Leiterer, Christian; Deckert-Gaudig, Tanja; Singh, Prabha; Wirth, Janina; Deckert, Volker; Fritzsche, Wolfgang

    2015-05-01

    Tip-enhanced Raman spectroscopy, a combination of Raman spectroscopy and scanning probe microscopy, is a powerful technique to detect the vibrational fingerprint of molecules at the nanometer scale. A metal nanoparticle at the apex of an atomic force microscope tip leads to a large enhancement of the electromagnetic field when illuminated with an appropriate wavelength, resulting in an increased Raman signal. A controlled positioning of individual nanoparticles at the tip would improve the reproducibility of the probes and is quite demanding due to usually serial and labor-intensive approaches. In contrast to commonly used submicron manipulation techniques, dielectrophoresis allows a parallel and scalable production, and provides a novel approach toward reproducible and at the same time affordable tip-enhanced Raman spectroscopy tips. We demonstrate the successful positioning of an individual plasmonic nanoparticle on a commercial atomic force microscope tip by dielectrophoresis followed by experimental proof of the Raman signal enhancing capabilities of such tips. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60.

    Science.gov (United States)

    Xu, Songjun; Elefant, Felice

    2015-01-01

    Disruption of epigenetic gene control mechanisms involving histone acetylation in the brain causes cognitive impairment, a debilitating hallmark of most neurodegenerative disorders. Histone acetylation regulates cognitive gene expression via chromatin packaging control in neurons. Unfortunately, the histone acetyltransferases (HATs) that generate such neural epigenetic signatures and their mechanisms of action remain unclear. Our recent findings provide insight into this question by demonstrating that Tip60 HAT action is critical for morphology and function of the mushroom body (MB), the learning and memory center in the Drosophila brain. We show that Tip60 is robustly produced in MB Kenyon cells and extending axonal lobes and that targeted MB Tip60 HAT loss results in axonal outgrowth disruption. Functional consequences of loss and gain of Tip60 HAT levels in the MB are evidenced by defects in memory. Tip60 ChIP-Seq analysis reveals enrichment for genes that function in cognitive processes and accordingly, key genes representing these pathways are misregulated in the Tip60 HAT mutant fly brain. Remarkably, increasing levels of Tip60 in the MB rescues learning and memory deficits resulting from Alzheimer's disease associated amyloid precursor protein (APP) induced neurodegeneration. Our studies highlight the potential of HAT activators as a therapeutic option for cognitive disorders.

  11. Modeling of Unsteady Sheet Cavitation on Marine Propeller Blades

    Directory of Open Access Journals (Sweden)

    Spyros A. Kinnas

    2003-01-01

    Full Text Available Unsteady sheet cavitation is very common on marine propulsor blades. The authors summarize a lifting-surface and a surface-panel model to solve for the unsteady cavitating flow around a propeller that is subject to nonaxisymmetric inflow. The time-dependent extent and thickness of the cavity were determined by using an iterative method. The cavity detachment was determined by applying the smooth detachment criterion in an iterative manner. A nonzeroradius developed vortex cavity model was utilized at the tip of the blade, and the trailing wake geometry was determined using a fully unsteady wake-alignment process. Comparisons of predictions by the two models and measurements from several experiments are given.

  12. Higher Education Act. Fact Sheet.

    Science.gov (United States)

    National Council on Disability, 2004

    2004-01-01

    This fact sheet highlights the challenges for students with disabilities in the nation's university system and recommends solutions that would result in better support systems for postsecondary students with disabilities. This document discusses several interrelated issues that impact student preparation and access to postsecondary education. The…

  13. Fact Sheet: Vulnerable Young Children

    Science.gov (United States)

    Shaw, Evelyn, Comp.; Goode, Sue, Comp.

    2008-01-01

    This fact sheet provides data on infants, toddlers and young children who are experiencing high stress as a result of a number of risk factors specifically identified in the Individuals with Disabilities Education Improvement Act of 2004 (IDEA 2004), including substantiated abuse or neglect, foster care placement, homelessness, exposure to family…

  14. Off-Balance Sheet Financing.

    Science.gov (United States)

    Adams, Matthew C.

    1998-01-01

    Examines off-balance sheet financing, the facilities use of outsourcing for selected needs, as a means of saving operational costs and using facility assets efficiently. Examples of using outside sources for energy supply and food services, as well as partnering with business for facility expansion are provided. Concluding comments address tax…

  15. Learning from Balance Sheet Visualization

    Science.gov (United States)

    Tanlamai, Uthai; Soongswang, Oranuj

    2011-01-01

    This exploratory study examines alternative visuals and their effect on the level of learning of balance sheet users. Executive and regular classes of graduate students majoring in information technology in business were asked to evaluate the extent of acceptance and enhanced capability of these alternative visuals toward their learning…

  16. Stabilization of Inviscid Vortex Sheets

    Science.gov (United States)

    Protas, Bartosz; Sakajo, Takashi

    2017-11-01

    In this study we investigate the problem of stabilizing inviscid vortex sheets via feedback control. Such models, expressed in terms of the Birkhoff-Rott equation, are often used to describe the Kevin-Helmholtz instability of shear layers and are known to be strongly unstable to small-scale perturbations. First, we consider the linear stability of a straight vortex sheet in the periodic setting with actuation in the form of an array of point vortices or sources located a certain distance away from the sheet. We establish conditions under which this system is controllable and observable. Next, using methods of the linear control theory, we synthesize a feedback control strategy which stabilizes a straight vortex sheet in the linear regime. Given the poor conditioning of the discretized problem, reliable solution of the resulting algebraic Riccati equation requires the use of high-precision arithmetic. Finally, we demonstrate that this control approach also succeeds in the nonlinear regime, provided the magnitude of the initial perturbation is sufficiently small.

  17. Magnetic Resonance Facility (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-03-01

    This fact sheet provides information about Magnetic Resonance Facility capabilities and applications at NREL's National Bioenergy Center. Liquid and solid-state analysis capability for a variety of biomass, photovoltaic, and materials characterization applications across NREL. NREL scientists analyze solid and liquid samples on three nuclear magnetic resonance (NMR) spectrometers as well as an electron paramagnetic resonance (EPR) spectrometer.

  18. Adipogenesis: forces that tip the scales

    DEFF Research Database (Denmark)

    MacDougald, Ormond A; Mandrup, Susanne

    2001-01-01

    factors reviewed include Wnt, transforming growth factor beta, inflammatory cytokines and prostaglandin F(2alpha). Tipping the scales towards or away from adipogenesis has profound implications for human health. In this review, we describe recent contributions to the field and will focus on factors...

  19. Tip Saves Energy, Money for Pennsylvania Plant

    Science.gov (United States)

    A wastewater treatment plant in Berks County, Pennsylvania is saving nearly $45,000 a year and reducing hundreds of metric tons of greenhouse gases since employing an energy conservation tip offered by the Water Protection Division in EPA’s R3 and PADEP.

  20. International Travel: Tips for Staying Healthy

    Science.gov (United States)

    ... Conditions Prevention and Wellness Staying Healthy Healthy Living Travel Occupational Health First Aid and Injury Prevention Crisis ... MoreDepression in Children and TeensRead MoreBMI Calculator Air Travel Health TipsTexting and DrivingTravel Needs for SeniorsFood PoisoningAcute ...

  1. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... Español Search FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, ... Biologics Animal & Veterinary Cosmetics Tobacco Products For Consumers Home For Consumers Consumer Updates Barbecue Basics: Tips to ...

  2. What Do You Mean, 'Tipping Point'?

    NARCIS (Netherlands)

    Nes, van E.H.; Shojaei Arani, M.; Staal, A.; Bolt, van der B.; Flores, Bernardo M.; Bathiany, S.; Scheffer, M.

    2016-01-01

    Over the past 10 years the use of the term ‘tipping point’ in the scientific literature has exploded. It was originally used loosely as a metaphor for the phenomenon that, beyond a certain threshold, runaway change propels a system to a new state. Although several specific mathematical definitions

  3. Direct calculation of wind turbine tip loss

    DEFF Research Database (Denmark)

    Wood, D.H.; Okulov, Valery; Bhattacharjee, D.

    2016-01-01

    . We develop three methods for the direct calculation of the tip loss. The first is the computationally expensive calculation of the velocities induced by the helicoidal wake which requires the evaluation of infinite sums of products of Bessel functions. The second uses the asymptotic evaluation...

  4. The Tipping Points of Technology Development

    Directory of Open Access Journals (Sweden)

    Tauno Kekäle

    2014-07-01

    Full Text Available The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product releases, resource allocation, sales forecasts and, ultimately, affects the profitability and even survival of a company. The tipping point itself is based on many stochastic and dynamic variables, and the process may at least partly be described as path-dependent. This paper analyses the tipping point from three aspects: (1 product performance, (2 features of the market and infrastructure (including related technologies and human network externalities, and (3 actions of the incumbents (including customer lock-in, systems lock-in, and sustaining innovation. The paper is based on the Bass s-curve idea and the technology trajectory concept proposed by Dosi. Three illustrative cases are presented to make the point of the multiple factors affecting technology acceptance and, thus, the tipping point. The paper also suggests outlines for further research in field of computer simulation.

  5. Tips for Airline Travelers with Sjogren's Syndrome

    Science.gov (United States)

    Tips for Airline Travelers with Sjögren’s Syndrome For more information on Sjogren's syndrome, visit the SSF Web site at www.sjogrens. ... org for more information on Sjögren’s syndrome. New airline rules can have a profound effect on those ...

  6. Final Technical Report: Electrohydrodynamic Tip Streaming

    Energy Technology Data Exchange (ETDEWEB)

    Basaran, Osman [Purdue Univ., West Lafayette, IN (United States)

    2016-01-06

    When subjected to strong electric fields, liquid drops and films form conical tips and emit thin jets from their tips. Such electrodydrodynamic (EDH) tip streaming or cone-jetting phenomena, which are sometimes referred to as electrospraying, occur widely in nature, e.g., in ejection of streams of small charged drops from pointed tips of raindrops in thunderclouds, and technology, e.g., in electrospray mass spectrometry or electric field-driven solvent extraction. More recently, EHD cone-jetting has emerged as a powerful technique for direct printing of solar cells, micro- and nano- particle production, and microencapsulation for controlled release. In many of the aforementioned situations, of equal importance to the processes by which one drop disintegrates to form several drops are those by which (a) two drops come together and coalesce and (b) two drops are coupled to form a double droplet system (DDS) or a capillary switch (CS). the main objective of this research program is to advance through simulation, theory, and experiment the breakup, coalescence, and oscillatory dynamics of single and pairs of charged as well as uncharged drops.

  7. Tip cells: master regulators of tubulogenesis?

    Science.gov (United States)

    Weavers, Helen; Skaer, Helen

    2014-07-01

    The normal development of an organ depends on the coordinated regulation of multiple cell activities. Focusing on tubulogenesis, we review the role of specialised cells or groups of cells that are selected from within tissue primordia and differentiate at the outgrowing tips or leading edge of developing tubules. Tip or leading cells develop distinctive patterns of gene expression that enable them to act both as sensors and transmitters of intercellular signalling. This enables them to explore the environment, respond to both tissue intrinsic signals and extrinsic cues from surrounding tissues and to regulate the behaviour of their neighbours, including the setting of cell fate, patterning cell division, inducing polarity and promoting cell movement and cell rearrangements by neighbour exchange. Tip cells are also able to transmit mechanical tension to promote tissue remodelling and, by interacting with the extracellular matrix, they can dictate migratory pathways and organ shape. Where separate tubular structures fuse to form networks, as in the airways of insects or the vascular system of vertebrates, specialised fusion tip cells act to interconnect disparate elements of the developing network. Finally, we consider their importance in the maturation of mature physiological function and in the development of disease. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  8. Strategic surfaces in sheet metal forming

    DEFF Research Database (Denmark)

    Olsson, David Dam; Andreasen, Jan Lasson; Bay, Niels

    Out-line: Introduction to tribology in sheet metal forming Developed strategic surfaces Tribological testing of strategic surfaces Conclusion......Out-line: Introduction to tribology in sheet metal forming Developed strategic surfaces Tribological testing of strategic surfaces Conclusion...

  9. Whooping Cough (Pertussis) - Fact Sheet for Parents

    Science.gov (United States)

    ... months 4 through 6 years Fact Sheet for Parents Color [2 pages] Español: Tosferina (pertussis) The best ... according to the recommended schedule. Fact Sheets for Parents Diseases and the Vaccines that Prevent Them Chickenpox ...

  10. Study of tip loss corrections using CFD rotor computations

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Zhu, Wei Jun; Sørensen, Jens Nørkær

    2014-01-01

    Tip loss correction is known to play an important role for engineering prediction of wind turbine performance. There are two different types of tip loss corrections: tip corrections on momentum theory and tip corrections on airfoil data. In this paper, we study the latter using detailed CFD compu...... and compared with CFD results for the NordTank 500 kW turbine and the NREL 5 MW turbine. Comparisons show that BEM with the new tip loss function can predict correctly the loading near the blade tip.......Tip loss correction is known to play an important role for engineering prediction of wind turbine performance. There are two different types of tip loss corrections: tip corrections on momentum theory and tip corrections on airfoil data. In this paper, we study the latter using detailed CFD...... computations for wind turbines with sharp tip. Using the technique of determination of angle of attack and the CFD results for a NordTank 500 kW rotor, airfoil data are extracted and a new tip loss function on airfoil data is derived. To validate, BEM computations with the new tip loss function are carried out...

  11. Diabetes Medicines

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends ...

  12. Herbal Medicine

    Science.gov (United States)

    ... for its scent, flavor, or therapeutic properties. Herbal medicines are one type of dietary supplement. They are ... and fresh or dried plants. People use herbal medicines to try to maintain or improve their health. ...

  13. Distant plasma sheet ion distributions during reconnection

    OpenAIRE

    Owen, C. J.; Mist, R. T.

    2001-01-01

    Previous models of the plasma sheet following reconnection and current sheet acceleration predict 'lima-bean' ion distributions. These are inconsistent with observational constraints. We postulate that following initial interaction with the current sheet, a fraction of outflow ions are backscattered and re-encounter the current sheet. Fermi acceleration processes then generate an additional high-energy outflow population. In the backscatter region these ions form a complete shell in velocity ...

  14. Crack tip fracture toughness of base glasses for dental restoration glass-ceramics using crack opening displacements.

    Science.gov (United States)

    Deubener, J; Höland, M; Höland, W; Janakiraman, N; Rheinberger, V M

    2011-10-01

    The critical stress intensity factor, also known as the crack tip toughness K(tip), was determined for three base glasses, which are used in the manufacture of glass-ceramics. The glasses included the base glass for a lithium disilicate glass-ceramic, the base glass for a fluoroapatite glass-ceramic and the base glass for a leucite glass-ceramic. These glass-ceramic are extensively used in the form of biomaterials in restorative dental medicine. The crack tip toughness was established by using crack opening displacement profiles under experimental conditions. The crack was produced by Vickers indentation. The crack tip toughness parameters determined for the three glass-ceramics differed quite significantly. The crack tip parameters of the lithium disilicate base glass and the leucite base glass were higher than that of the fluoroapatite base glass. This last material showed glass-in-glass phase separation. The discussion of the results clearly shows that the droplet glass phase is softer than the glass matrix. Therefore, the authors conclude that a direct relationship exists between the chemical nature of the glasses and the crack tip parameter. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Resistance Spot Welding of AA5052 Sheet Metal of Dissimilar Thickness

    Science.gov (United States)

    Mat Din, N. A.; Zuhailawati, H.; Anasyida, A. S.

    2016-02-01

    Resistance spot welding of dissimilar thickness of AA5052 aluminum alloy was performed in order to investigate the effect of metal thickness on the weldment strength. Resistance spot welding was done using a spot welder machine available in Coraza Systems Sdn Bhd using a hemispherical of chromium copper electrode tip with radius of 6.00 mm under 14 kA of current and 0.02 bar of pressure for all thickness combinations. Lap joint configuration was produced between 2.0 mm thick sheet and 1.2 - 3.2 mm thick sheet, respectively. Microstructure of joint showed asymmetrical nugget shape that was larger on the thicker side indicating larger molten metal volume. Joint 2.0 mm x 3.2 mm sheets has the lowest hardness in both transverse direction and through thickness direction because less heat left in the weld nugget. The microstructure shows that this joint has coarse grains of HAZ. As thickness of sheet metal increased, the failure load of the joints increased. However, there was no linear correlation established between joint strength and metal thickness due to different shape of fusion zone in dissimilar thickness sheet metal.

  16. Construction of Modular Hydrogel Sheets for Micropatterned Macro-scaled 3D Cellular Architecture.

    Science.gov (United States)

    Son, Jaejung; Bae, Chae Yun; Park, Je-Kyun

    2016-01-11

    Hydrogels can be patterned at the micro-scale using microfluidic or micropatterning technologies to provide an in vivo-like three-dimensional (3D) tissue geometry. The resulting 3D hydrogel-based cellular constructs have been introduced as an alternative to animal experiments for advanced biological studies, pharmacological assays and organ transplant applications. Although hydrogel-based particles and fibers can be easily fabricated, it is difficult to manipulate them for tissue reconstruction. In this video, we describe a fabrication method for micropatterned alginate hydrogel sheets, together with their assembly to form a macro-scale 3D cell culture system with a controlled cellular microenvironment. Using a mist form of the calcium gelling agent, thin hydrogel sheets are easily generated with a thickness in the range of 100 - 200 µm, and with precise micropatterns. Cells can then be cultured with the geometric guidance of the hydrogel sheets in freestanding conditions. Furthermore, the hydrogel sheets can be readily manipulated using a micropipette with an end-cut tip, and can be assembled into multi-layered structures by stacking them using a patterned polydimethylsiloxane (PDMS) frame. These modular hydrogel sheets, which can be fabricated using a facile process, have potential applications of in vitro drug assays and biological studies, including functional studies of micro- and macrostructure and tissue reconstruction.

  17. Aspirin to Zoloft: Ways Medicines Work

    Science.gov (United States)

    ... How Do Drugs Work?" available from the RCSB Protein Data Bank. Images courtesy of David S. Goodsell, The Scripps Research Institute. Learn more: How Medicines Work Fact Sheet How Do Drugs Work? ... Drugs For Proteins, Form Shapes Function This Inside Life Science article ...

  18. 21 CFR 880.5180 - Burn sheet.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Burn sheet. 880.5180 Section 880.5180 Food and... Burn sheet. (a) Identification. A burn sheet is a device made of a porous material that is wrapped aroung a burn victim to retain body heat, to absorb wound exudate, and to serve as a barrier against...

  19. Simulation of stationary sheet metal cutting processes

    NARCIS (Netherlands)

    Wisselink, H.H.; Huetink, Han

    1998-01-01

    In stationary sheet metal cutting processes, like guillotining and slitting, the sheet is cut progressively from one end to the other. This in contrary with transient processes (blanking) where the sheet is cut at once. Where transient shearing processes can be modelled in 2-D (plain strain or

  20. Tips for Good Health in Later Life: For Older Women

    Science.gov (United States)

    ... Geriatrics Osteoporosis Prevention Related Documents PDF Tips for Good Health in Later Life: For Older Women Download Join our e-newsletter! Resources Tips for Good Health in Later Life: For Older Women Tools ...

  1. Tips to Make Fast Food Friendlier for Kids

    Science.gov (United States)

    ... Workplace Food and Beverage Toolkit Tips to Make Fast Food Friendlier for Kids Updated:Feb 6,2017 Finding ... reheated or eaten on the road. But when fast food is your only option, try these tips to ...

  2. Cytology of root tips of Dioscoreophyllum cumminsii (STAPF) diel ...

    African Journals Online (AJOL)

    , University of Nigeria Nsukka. Root tips for the chromosome work were obtained from three sources: runners originating from main vine; sprouting pieces of tubers and redifferentiated root tips from callus. The results showed that normal ...

  3. The last British-Irish Ice Sheet: A data-rich environment for ice sheet modelling

    Science.gov (United States)

    Ely, Jeremy; Clark, Chris; Hindmarsh, Richard; Bradley, Sarah

    2017-04-01

    In order to simulate the future dynamics of the Greenland and Antarctic ice sheets, robust numerical models validated by observations of past ice sheet behaviour are required. The extent and dynamics of contemporary ice sheets have been observed at a decadal scale. But a much longer record of ice sheet behaviour (10 ka) can be collated by studying the evidence left behind by palaeo-ice sheets. Extensive geomorphological and geochronological evidence for the past behaviour of the last British-Irish Ice Sheet has been gathered through over 150 years of research and BRITICE-CHRONO, a recent consortium project. This large volume of empirical evidence makes the last British-Irish Ice Sheet one of the best constrained palaeo-ice sheets in the world, and a data-rich environment for ice sheet modelling experiments. Yet, integrating this data and its associated uncertainty and abstraction into ice sheet modelling experiments remains challenging. Here we summarise the available geomorphological and geochronological data and discuss how this will be integrated into ice sheet modelling experiments. Several packages of data, each with its own associated level of interpretation (ranging from raw data to empirically reconstructed ice sheet margins), will be made available to the ice-sheet modelling community. Furthermore, we demonstrate our approach to simulating the empirically reconstructed behaviour of the British-Irish Ice Sheet through a series of ice sheet modelling experiments which account for relative sea level change, and uncertainty in empirically reconstructed ice sheet extent.

  4. Geometry of thin liquid sheet flows

    Science.gov (United States)

    Chubb, Donald L.; Calfo, Frederick D.; Mcconley, Marc W.; Mcmaster, Matthew S.; Afjeh, Abdollah A.

    1994-01-01

    Incompresible, thin sheet flows have been of research interest for many years. Those studies were mainly concerned with the stability of the flow in a surrounding gas. Squire was the first to carry out a linear, invicid stability analysis of sheet flow in air and compare the results with experiment. Dombrowski and Fraser did an experimental study of the disintegration of sheet flows using several viscous liquids. They also detected the formulation of holes in their sheet flows. Hagerty and Shea carried out an inviscid stability analysis and calculated growth rates with experimental values. They compared their calculated growth rates with experimental values. Taylor studied extensively the stability of thin liquid sheets both theoretically and experimentally. He showed that thin sheets in a vacuum are stable. Brown experimentally investigated thin liquid sheet flows as a method of application of thin films. Clark and Dumbrowski carried out second-order stability analysis for invicid sheet flows. Lin introduced viscosity into the linear stability analysis of thin sheet flows in a vacuum. Mansour and Chigier conducted an experimental study of the breakup of a sheet flow surrounded by high-speed air. Lin et al. did a linear stability analysis that included viscosity and a surrounding gas. Rangel and Sirignano carried out both a linear and nonlinear invisid stability analysis that applies for any density ratio between the sheet liquid and the surrounding gas. Now there is renewed interest in sheet flows because of their possible application as low mass radiating surfaces. The objective of this study is to investigate the fluid dynamics of sheet flows that are of interest for a space radiator system. Analytical expressions that govern the sheet geometry are compared with experimental results. Since a space radiator will operate in a vacuum, the analysis does not include any drag force on the sheet flow.

  5. AFM tip-sample convolution effects for cylinder protrusions

    Science.gov (United States)

    Shen, Jian; Zhang, Dan; Zhang, Fei-Hu; Gan, Yang

    2017-11-01

    A thorough understanding about the AFM tip geometry dependent artifacts and tip-sample convolution effect is essential for reliable AFM topographic characterization and dimensional metrology. Using rigid sapphire cylinder protrusions (diameter: 2.25 μm, height: 575 nm) as the model system, a systematic and quantitative study about the imaging artifacts of four types of tips-two different pyramidal tips, one tetrahedral tip and one super sharp whisker tip-is carried out through comparing tip geometry dependent variations in AFM topography of cylinders and constructing the rigid tip-cylinder convolution models. We found that the imaging artifacts and the tip-sample convolution effect are critically related to the actual inclination of the working cantilever, the tip geometry, and the obstructive contacts between the working tip's planes/edges and the cylinder. Artifact-free images can only be obtained provided that all planes and edges of the working tip are steeper than the cylinder sidewalls. The findings reported here will contribute to reliable AFM characterization of surface features of micron or hundreds of nanometers in height that are frequently met in semiconductor, biology and materials fields.

  6. Mechanisms for enlarging lesion size during irrigated tip radiofrequency ablation

    DEFF Research Database (Denmark)

    Petersen, Helen Høgh; Roman-Gonzalez, Javier; Johnson, Susan B

    2004-01-01

    INTRODUCTION: Irrigated tip radiofrequency ablation of cardiac arrhythmias was developed to increase the size of the radiofrequency-induced lesion, since cooling of the electrode tip allows use of higher power settings. The purpose of this study was to determine if the increased lesion size during......(3) (P radiofrequency irrigated-tip ablation is that higher power levels can be used...

  7. Modular design of AFM probe with sputtered silicon tip

    DEFF Research Database (Denmark)

    Rasmussen, Peter; Thaysen, Jacob; Bouwstra, Siebe

    2001-01-01

    of the thin films constituting the cantilever. The AFM probe has an integrated tip made of a thick sputtered silicon layer, which is deposited after the probe has been defined and just before the cantilevers are released. The tips are so-called rocket tips made by reactive ion etching. We present probes...

  8. Ice sheet hydrology from observations

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Peter (Dept. of Physical Geography and Quaternary Geology, Stockholm Univ-, Stockholm (Sweden))

    2010-11-15

    The hydrological systems of ice sheets are complex. Our view of the system is split, largely due to the complexity of observing the systems. Our basic knowledge of processes have been obtained from smaller glaciers and although applicable in general to the larger scales of the ice sheets, ice sheets contain features not observable on smaller glaciers due to their size. The generation of water on the ice sheet surface is well understood and can be satisfactorily modeled. The routing of water from the surface down through the ice is not complicated in terms of procat has been problematic is the way in which the couplings between surface and bed has been accomplished through a kilometer of cold ice, but with the studies on crack propagation and lake drainage on Greenland we are beginning to understand also this process and we know water can be routed through thick cold ice. Water generation at the bed is also well understood but the main problem preventing realistic estimates of water generation is lack of detailed information about geothermal heat fluxes and their geographical distribution beneath the ice. Although some average value for geothermal heat flux may suffice, for many purposes it is important that such values are not applied to sub-regions of significantly higher fluxes. Water generated by geothermal heat constitutes a constant supply and will likely maintain a steady system beneath the ice sheet. Such a system may include subglacial lakes as steady features and reconfiguration of the system is tied to time scales on which the ice sheet geometry changes so as to change pressure gradients in the basal system itself. Large scale re-organization of subglacial drainage systems have been observed beneath ice streams. The stability of an entirely subglacially fed drainage system may hence be perturbed by rapid ice flow. In the case of Antarctic ice streams where such behavior has been observed, the ice streams are underlain by deformable sediments. It is

  9. Ohm's law for a current sheet

    Science.gov (United States)

    Lyons, L. R.; Speiser, T. W.

    1985-01-01

    The paper derives an Ohm's law for single-particle motion in a current sheet, where the magnetic field reverses in direction across the sheet. The result is considerably different from the resistive Ohm's law often used in MHD studies of the geomagnetic tail. Single-particle analysis is extended to obtain a self-consistency relation for a current sheet which agrees with previous results. The results are applicable to the concept of reconnection in that the electric field parallel to the current is obtained for a one-dimensional current sheet with constant normal magnetic field. Dissipated energy goes directly into accelerating particles within the current sheet.

  10. High Frequency Multiple Shoot Induction of Curculigo orchioides Gaertn.: Shoot Tip V/S Rhizome Disc

    Directory of Open Access Journals (Sweden)

    K. S. Nagesh

    2008-09-01

    Full Text Available Curculigo orchioides Gaertn. is an endangered medicinal plant with anticancer properties. The rhizome and tuberous roots of the plant have been used extensively in India in indigenous medicine. Due to its multiple uses, the demand for Curculigo orchioides is constantly on the rise; however, the supply is rather erratic and inadequate. Destructive harvesting, combined with habitat destruction in the form of deforestation has aggravated the problem. The plant is now considered ‘endangered’ in its natural habitat. Therefore, the need for conservation of this plant is crucial. Here, we describe a successful protocol for multiple shoot induction of C. orchioides using shoot tip and rhizome disc. We find that proximal rhizome discs are optimal for high frequency shoot bud formation than shoot tip and distal rhizome disc. We observed a synergistic effect between 6-benzylaminopurine (BAP and kinetin (KN (each at 1 mg/L on the regeneration of shoot buds from proximal rhizome disc than shoot tip explant. Optimum root induction was achieved on half-strength MS liquid medium supplemented with 1 mg/L of indole-3-butyric acid (IBA. The in vitro raised plantlets were acclimatized in green house and successfully transplanted to natural condition with 90% survival.

  11. Technology to Market Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-02-01

    This fact sheet is an overview of the Technology to Market subprogram at the U.S. Department of Energy SunShot Initiative. The SunShot Initiative’s Technology to Market subprogram builds on SunShot’s record of moving groundbreaking and early-stage technologies and business models through developmental phases to commercialization. Technology to Market targets two known funding gaps: those that occur at the prototype commercialization stage and those at the commercial scale-up stage.

  12. Twelve tips for facilitating Millennials' learning.

    Science.gov (United States)

    Roberts, David H; Newman, Lori R; Schwartzstein, Richard M

    2012-01-01

    The current, so-called "Millennial" generation of learners is frequently characterized as having deep understanding of, and appreciation for, technology and social connectedness. This generation of learners has also been molded by a unique set of cultural influences that are essential for medical educators to consider in all aspects of their teaching, including curriculum design, student assessment, and interactions between faculty and learners.  The following tips outline an approach to facilitating learning of our current generation of medical trainees.  The method is based on the available literature and the authors' experiences with Millennial Learners in medical training.  The 12 tips provide detailed approaches and specific strategies for understanding and engaging Millennial Learners and enhancing their learning.  With an increased understanding of the characteristics of the current generation of medical trainees, faculty will be better able to facilitate learning and optimize interactions with Millennial Learners.

  13. Reconstruction of nasal tip and columella.

    Science.gov (United States)

    Faris, Callum; Vuyk, Hade D

    2011-02-01

    Reconstruction of nasal tip and columella defects is demanding area with a range of reconstructive options, varying in complexity depending on requirements from simple skin grafting to multiple stage reconstruction with regional flaps. A framework is suggested to aid the reader in choice of reconstruction by classifying the defect based on size and the requirements of one to three layer (full thickness) reconstruction. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. Oracle Apex reporting tips and tricks

    CERN Document Server

    Bara, George

    2013-01-01

    Take advantage of all the exciting Reporting features of Oracle Application Express 4.2. Designed for a hands-on approach, this book contains in-depth practical guidelines from George Bara, a well-known Oracle Apex expert and blogger. From Classic to Interactive Reports, Web Services and Pdf Printing, "Oracle Apex Reporting Tips & Tricks" is a must-have for all database developers that want to make the most out of the Oracle Apex reporting engine.

  15. Exodontia: tips and techniques for better outcomes.

    Science.gov (United States)

    Dym, Harry; Weiss, Adam

    2012-01-01

    This article reviews and highlights exodontia tips as well as new techniques to make simple and complex exodontia more predictable and efficient with improved patient outcomes. A discussion of a powered periotome that has been developed to aid in the atraumatic extraction of teeth and another new device, the piezosurgery, increasingly used for outpatient oral surgery procedures are included. Physics forceps, a new type of exodontia forceps, is also discussed in this article. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. Impact of 1.5°C global warming on the Greenland and Antarctic ice sheets

    Science.gov (United States)

    Ritz, Catherine; Pattyn, Frank

    2017-04-01

    For strengthening the global response to climate change, it is crucial to assess to what extent limiting global warming to low values may reduce the impacts on society. To tackle this issue, the IPCC has decided to provide a special report in 2018 on the impacts of global warming of 1.5°C above pre-industrial levels and related global greenhouse gas emission pathways. Ice sheets are well known contributors to sea level rise and many studies have aimed to provide projections of their future contribution in response to climate change, although the focus was often on worst-case scenarios. Here we propose to review the present knowledge of how the ice sheets could be affected in the case of a limited warming of 1.5°C to 2.0°C. We will review the various processes and feedbacks known to induce ice sheets vulnerability. They are different for Greenland, where we know that the surface mass balance plays a crucial role, and Antarctica where the major risk is marine ice sheet instability. One point of interest is to define, in terms of local forcing, the tipping points associated with these processes. We note that limiting global warming to 1.5°C may mean substantially more warming in the polar regions. This polar amplification can be assessed from experiments following the RCP2.6 scenario that have been carried out in recent (post IPCC AR5) studies. This scenario can be considered as an upper limit for 1.5°C. The final question concerns the long term (millennial) impact. There is a general consensus that there are tipping points both for Greenland and Antarctica, which potentially lead to irreversible mass loss. We will review the current knowledge of how long it takes to reach these tipping points and whether subsequent ice-sheet demise is, indeed, unstoppable.

  17. Tip loss correction for actuator / Navier Stokes computations

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Sørensen, Jens Nørkær; Mikkelsen, Robert Flemming

    2004-01-01

    The new tip loss correction, initially developed for ID BEM computations [1], is now extended to 2D Actuator Disc / Navier-Stokes (AD/NS) computations and 3D Actuator Line / Navier-Stokes (AL/NS) computations. As shown in the paper, the tip loss correction is an important and necessary step...... for actuator / Navier-Stokes models. Comparisons of the present results with those obtained from a EM code with new tip correction and experimental data show that the tip loss correction is correctly implemented in the actuator / Navier-Stokes models. The results demonstrate also that difference between......, Actuator Line, Navier-Stokes equations, Tip loss correction....

  18. Selection of case studies describing PICC tip malposition.

    Science.gov (United States)

    Jackson, Andrew; Buttle, Andrew

    2016-07-28

    This article presents a number of case studies, spanning a 12-month period, associated with peripherally inserted central catheter (PICC) tip location. The aim is to generate debate around the journey PICC tips may take; it is not the purpose of this article to debate technological solutions to the issue of PICC tip location. The discussion of each case illustrates a wide range of potential aberrant PICC tip locations and offers an insight into how the abberant tip location was resolved in each case.

  19. Towards a tipping point in responding to change: rising costs, fewer options for Arctic and global societies.

    Science.gov (United States)

    Huntington, Henry P; Goodstein, Eban; Euskirchen, Eugénie

    2012-02-01

    Climate change incurs costs, but government adaptation budgets are limited. Beyond a certain point, individuals must bear the costs or adapt to new circumstances, creating political-economic tipping points that we explore in three examples. First, many Alaska Native villages are threatened by erosion, but relocation is expensive. To date, critically threatened villages have not yet been relocated, suggesting that we may already have reached a political-economic tipping point. Second, forest fires shape landscape and ecological characteristics in interior Alaska. Climate-driven changes in fire regime require increased fire-fighting resources to maintain current patterns of vegetation and land use, but these resources appear to be less and less available, indicating an approaching tipping point. Third, rapid sea level rise, for example from accelerated melting of the Greenland ice sheet, will create a choice between protection and abandonment for coastal regions throughout the world, a potential global tipping point comparable to those now faced by Arctic communities. The examples illustrate the basic idea that if costs of response increase more quickly than available resources, then society has fewer and fewer options as time passes.

  20. The development of fabrication techniques for europia/iron cermet tips for coarse-control arms in DIDO and PLUTO

    International Nuclear Information System (INIS)

    Moore, D.A.; Tarrant, E.A.

    1980-11-01

    The applicability of cermet-fabrication techniques to the production of europia/iron cermets for use as coarse-control arm tips in the materials test reactors DIDO and PLUTO has been investigated. Spheroids of europia were prepared by a dry agglomeration process. These were sintered, dispersed in iron powder and pressed into plates; the plates were then sintered to densify the iron matrix. These stages were optimised to produce a strong cermet with a europia density of >= 2.75 g/cm 3 . The uniformity of distribution of the absorber particles was confirmed by radiography, and adequate neutron-absorption worth by measurements carried out in the GLEEP reactor. An outline flow sheet has been prepared for the manufacture of europia/iron cermet plates suitable for use in the tips of DIDO and PLUTO coarse-control arms. (author)

  1. Progressive failure of sheeted rock slopes: the 2009–2010 Rhombus Wall rock falls in Yosemite Valley, California, USA

    Science.gov (United States)

    Stock, Greg M.; Martel, Stephen J.; Collins, Brian D.; Harp, Edwin L.

    2012-01-01

    Progressive rock-fall failures in natural rock slopes are common in many environments, but often elude detailed quantitative documentation and analysis. Here we present high-resolution photography, video, and laser scanning data that document spatial and temporal patterns of a 15-month-long sequence of at least 14 rock falls from the Rhombus Wall, a sheeted granitic cliff in Yosemite Valley, California. The rock-fall sequence began on 26 August 2009 with a small failure at the tip of an overhanging rock slab. Several hours later, a series of five rock falls totaling 736 m3progressed upward along a sheeting joint behind the overhanging slab. Over the next 3 weeks, audible cracking occurred on the Rhombus Wall, suggesting crack propagation, while visual monitoring revealed opening of a sheeting joint adjacent to the previous failure surface. On 14 September 2009 a 110 m3 slab detached along this sheeting joint. Additional rock falls between 30 August and 20 November 2010, totaling 187 m3, radiated outward from the initial failure area along cliff (sub)parallel sheeting joints. We suggest that these progressive failures might have been related to stress redistributions accompanying propagation of sheeting joints behind the cliff face. Mechanical analyses indicate that tensile stresses should occur perpendicular to the cliff face and open sheeting joints, and that sheeting joints should propagate parallel to a cliff face from areas of stress concentrations. The analyses also account for how sheeting joints can propagate to lengths many times greater than their depths behind cliff faces. We posit that as a region of failure spreads across a cliff face, stress concentrations along its margin will spread with it, promoting further crack propagation and rock falls.

  2. Influence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration.

    Science.gov (United States)

    Gao, Hui; Li, Bei; Zhao, Lingzhou; Jin, Yan

    2015-01-01

    Periodontal regeneration is an important part of regenerative medicine, with great clinical significance; however, the effects of nanotopography on the functions of periodontal ligament (PDL) stem cells (PDLSCs) and on PDLSC sheet based periodontal regeneration have never been explored. Titania nanotubes (NTs) layered on titanium (Ti) provide a good platform to study this. In the current study, the influence of NTs of different tube size on the functions of PDLSCs was observed. Afterward, an ectopic implantation model using a Ti/cell sheets/hydroxyapatite (HA) complex was applied to study the effect of the NTs on cell sheet based periodontal regeneration. The NTs were able to enhance the initial PDLSC adhesion and spread, as well as collagen secretion. With the Ti/cell sheets/HA complex model, it was demonstrated that the PDLSC sheets were capable of regenerating the PDL tissue, when combined with bone marrow mesenchymal stem cell (BMSC) sheets and HA, without the need for extra soluble chemical cues. Simultaneously, the NTs improved the periodontal regeneration result of the ectopically implanted Ti/cell sheets/HA complex, giving rise to functionally aligned collagen fiber bundles. Specifically, much denser collagen fibers, with abundant blood vessels as well as cementum-like tissue on the Ti surface, which well-resembled the structure of natural PDL, were observed in the NT5 and NT10 sample groups. Our study provides the first evidence that the nanotopographical cues obviously influence the functions of PDLSCs and improve the PDLSC sheet based periodontal regeneration size dependently, which provides new insight to the periodontal regeneration. The Ti/cell sheets/HA complex may constitute a good model to predict the effect of biomaterials on periodontal regeneration.

  3. [Expedition medicine].

    Science.gov (United States)

    Donlagić, Lana

    2009-01-01

    Expedition and wildeness medicine is a term that combines rescue medicine, sport medicine as well as more specific branches as polar or high altitude medicine. It is being intensively studied both at the reaserch institutes and on expeditions. Ophtalmologists are concentrated on the reaserch of HARH (High Altitude Retinal Hemorrhage), neurologists on HACE reaserch (High Altitude Cerebral Edema), psychologists are developing tests to decsribe cognitive functions and many physicians are being trained to work in extreme enviroment. The result of all this effort are numerous new findings in pathophysiology and therapy of altitude illness, increased security on expedition and further development of expeditionism.

  4. Nuclear medicine

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The area of nuclear medicine, the development of artificially produced radioactive isotopes for medical applications, is relatively recent. Among the subjects covered in a lengthy discussion are the following: history of development; impact of nuclear medicine; understanding the most effective use of radioisotopes; most significant uses of nuclear medicine radioimmunoassays; description of equipment designed for use in the field of nuclear medicine (counters, scanning system, display systems, gamma camera); description of radioisotopes used and their purposes; quality control. Numerous historical photographs are included. 52 refs

  5. BARLEY BALANCE SHEET IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Dragoş Mihai MEDELETE

    2013-01-01

    Full Text Available Barley is one of the most important cereal grown in Romania, after corn and wheat. This is based, at least on considerations of cultivated area (413.4 thousand ha - average 2007-2009, but also because of the multiple uses it may have (Food, feed, industrial raw materials, etc.. Presentation of food balance we consider interesting in terms of supply and demand components: production, imports, stocks, exports, seeds, feed consumption, industrial raw materials, food and other useslosses. On the basis of total volume of supply and demand we could determine the balance sheet at nationa level for the product.

  6. Vietnamese Hurricane Response Fact Sheets

    Science.gov (United States)

    Các tờ dữ kiện được cung cấp nơi đây mô tả vai trò của EPA trong việc đáp ứng với bão và cách các chương trình cụ thể cung cấp sự hỗ trợ. The Vietnamese fact sheets provided here describe EPA's role in a hurricane response.

  7. Laser welding of sheet metals

    Science.gov (United States)

    Xie, Jian

    Laser welding of sheet metals is an important application of high power lasers, and has many advantages over conventional welding techniques. Laser welding has a great potential to replace other welding technique in the car-body manufacturing because of high laser weld quality and relatively low manufacturing cost associated with the laser technique. However, a few problems related to the laser welding of sheet metals limit its applications in industries. To have a better understanding of the welding process, laser welding experimental studies and theoretical analysis are necessary. Temperature-dependent absorptivities of various metals are obtained theoretically for COsb2, COIL (Chemical Oxygen-Iodine Laser) and Nd:YAG lasers. It is found that the absorptivities for COIL and Nd:YAG lasers are 2.84 and 3.16 times higher than for the COsb2 laser, and the absorptivity increases with increasing temperature of the metals. Surface roughness and oxide films can enhance the absorption significantly. The reflectivity of as-received steel sheets decreases from 65-80% to 30-40% with surface oxide films for COsb2 lasers. Laser welding experiments show that the tensile strengths of the weld metals are higher than the base metals. For samples with surface oxide films, the oxygen concentration in the weld metals is found to be higher than in the specimens without oxidation, and the toughness of the weld metals is degraded. When steel powders are added to bridge the gap between two sheets, the oxygen content in the weld metals decreases and the toughness increases. A mathematical model is developed for the melt depth due to a stationary laser beam. The model results show that the melt depth increases rapidly with time at the beginning of laser irradiation and then increases slowly. Also, the melt depth is found to increase rapidly with laser intensities and then increases slowly for higher intensity. The average rate of melting and the times to reach the melting and boiling

  8. AI applications in sheet metal forming

    CERN Document Server

    Hussein, Hussein

    2017-01-01

    This book comprises chapters on research work done around the globe in the area of artificial intelligence (AI) applications in sheet metal forming. The first chapter offers an introduction to various AI techniques and sheet metal forming, while subsequent chapters describe traditional procedures/methods used in various sheet metal forming processes, and focus on the automation of those processes by means of AI techniques, such as KBS, ANN, GA, CBR, etc. Feature recognition and the manufacturability assessment of sheet metal parts, process planning, strip-layout design, selecting the type and size of die components, die modeling, and predicting die life are some of the most important aspects of sheet metal work. Traditionally, these activities are highly experience-based, tedious and time consuming. In response, researchers in several countries have applied various AI techniques to automate these activities, which are covered in this book. This book will be useful for engineers working in sheet metal industri...

  9. Vulnerable Medicine

    Science.gov (United States)

    Bochner, Arthur P.

    2009-01-01

    In "Narrative Medicine: Honoring the Stories of Illness," Rita Charon paints an original and humane portrait of what it can mean to be a doctor, to live a life immersed in sickness and dedicated to wellness. Charon drops the veil, inviting readers to look at the secret, subjective, emotional face of medicine, a zone of self-censored feelings and…

  10. Relocalization of human chromatin remodeling cofactor TIP48 in mitosis

    International Nuclear Information System (INIS)

    Sigala, Barbara; Edwards, Mina; Puri, Teena; Tsaneva, Irina R.

    2005-01-01

    TIP48 is a highly conserved eukaryotic AAA + protein which is an essential cofactor for several complexes involved in chromatin acetylation and remodeling, transcriptional and developmental regulation and nucleolar organization and trafficking. We show that TIP48 abundance in HeLa cells did not change during the cell cycle, nor did its distribution in various biochemical fractions. However, we observed distinct changes in the subcellular localization of TIP48 during M phase using immunofluorescence microscopy. Our studies demonstrate that in interphase cells TIP48 was found mainly in the nucleus and exhibited a distinct localization in the nuclear periphery. As the cells entered mitosis, TIP48 was excluded from the condensing chromosomes but showed association with the mitotic apparatus. During anaphase, some TIP48 was detected in the centrosome colocalizing with tubulin but the strongest staining appeared in the mitotic equator associated with the midzone central spindle. Accumulation of TIP48 in the midzone and the midbody was observed in late telophase and cytokinesis. This redeployment of TIP48 during anaphase and cytokinesis was independent of microtubule assembly. The relocation of endogenous TIP48 to the midzone/midbody under physiological conditions suggests a novel and distinct function for TIP48 in mitosis and possible involvement in the exit of mitosis

  11. Numerical Simulation of LVAD Inflow Cannulas with Different Tip

    Directory of Open Access Journals (Sweden)

    Guang-Mao Liu

    2012-01-01

    Full Text Available The tip structure of LVAD inflow cannula is one of major factors to lead adverse events such as thrombosis and suction leading to obstruction. In this research, four kinds of tips that had been used in inflow cannulas were selected and designed. The flow field of the four inflow cannulas inserted into the apex of left ventricle (LV was numerically computed by computational fluid dynamics. The flow behavior was analyzed in order to compare the blood compatibility and suction in left ventricle and cannulas after the inflow cannulas with different tips were inserted to the apex of LV. The results showed that the cannula tip structure affected the LVAD performance. Among these four cannulas, the trumpet-tipped inflow cannula owned the best performance in smooth flow velocity distribution without backflow or low-velocity flow so that it was the best in blood compatibility. Nevertheless, the caged tipped cannula was the worst in blood compatibility. And the blunt-tipped and beveled tipped inflow cannulas may obstruct more easily than trumpet and caged tipped inflow cannulas because of their shape. The study indicated that the trumpet tip was the most preferable for the inflow cannula of long-term LVAD.

  12. [Plastic micro-tips for drug delivery].

    Science.gov (United States)

    Muslija, A; Guber, A E; Heckele, M; Herrmann, D; Pfleging, W; Schaller, Th

    2002-01-01

    Removal or exact transfer of minimum substance volumes from reservoirs or microfluidic systems may be accomplished by means of miniaturized tips with integrated through-going capillaries. Applications in biomedical engineering, e.g. for the application of drugs, or in life sciences, e.g. equipping of microarrays, require the use of disposable plastic products for hygienic reasons and reasons of costs. For this purpose, a method to fabricate microtips out of plastic by doublesided molding has been developed at the Forschungszentrum Karlsruhe.

  13. Semi-empirical crack tip analysis

    Science.gov (United States)

    Chudnovsky, A.; Ben Ouezdon, M.

    1988-01-01

    Experimentally observed crack opening displacements are employed as the solution of the multiple crack interaction problem. Then the near and far fields are reconstructed analytically by means of the double layer potential technqiue. Evaluation of the effective stress intensity factor resulting from the interaction of the main crack and its surrounding crazes in addition to the remotely applied load is presented as an illustrative example. It is shown that crazing (as well as microcracking) may constitute an alternative mechanism to Dugdale-Berenblatt models responsible for the cancellation of the singularity at the crack tip.

  14. Steel Sheet Pile Walls in Soft Soil

    OpenAIRE

    Kort, D.A.

    2002-01-01

    For almost a century, steel sheet pile walls are applied worldwide as earth retaining structures for excavations and quay walls. Within the framework of the development of European structural codes for Civil Engineering works, the Eurocodes, Eurocode 3 Part 5 for design of steel sheet pile walls was issued in 1997. This code offers possibilities for cheaper and safer steel sheet piling, in comparison with the existing design criteria used in most countries. Two of these design criteria with w...

  15. Hydraulic structures with defective sheet pile walls

    OpenAIRE

    Ahmed, Ashraf A.; Johnston, Harold T.; Oyedele, Lukumon

    2013-01-01

    A sheet pile wall driven to form a barrier wall below the floor of a hydraulic structure is frequently assumed to be watertight. Although the leakage through the interlocks of the sheet piles is usually small, damage and other factors can result in significant leakage. Consequently, this assumption is rarely, if ever, satisfied in reality. The present study used a finite-element model to investigate the effect of leaks through sheet piles driven under the floor of a hydraulic structure on see...

  16. Application of atelocollagen sheet for sellar reconstruction.

    Science.gov (United States)

    Goto, Yuko; Oshino, Satoru; Shimizu, Takeshi; Saitoh, Youichi

    2016-05-01

    We aimed to evaluate combined use of atelocollagen sheet and fibrin glue for sellar reconstruction. Experiment 1: A plastic chamber was prepared with a hydroxyapatite lid with a hole of 10mm in diameter at its center, covered with a Gore-Tex sheet (W.L. Gore & Associates, Tokyo, Japan) 15mm in diameter and sealed with a combination of fibrin glue sealant and either atelocollagen sheet or polyglycolic acid (PGA) sheet. Air was injected into the chamber and the pressure at which air leakage occurred was measured under each situation. Mean (±standard deviation) leakage pressure was 816±162mmH2O for atelocollagen sheet (n=5), significantly higher than the 557±130mmH2O for PGA sheet (n=5, p<0.05, Wilcoxon test). Experiment 2: Bilateral 5mm bone windows were made in the temporal bone in eight rats. The surgical cavities were filled with one of four materials (fibrin glue only; fibrin glue and atelocollagen sheet; PGA sheet; or autologous fat tissue). Histological changes including the status of implanted materials and inflammatory responses were investigated 2 and 5weeks after the procedures. Both atelocollagen and PGA sheets remained at 5weeks after implantation, whereas fibrin glue and fat tissue were absorbed and undetectable at 2weeks. Inflammatory cell accumulation was less around the atelocollagen sheet compared to the PGA sheet. The combination of atelocollagen sheet and fibrin glue sealant showed sufficient adhesion force and favorable tissue affinity, suggesting this combination as a feasible material in sellar reconstruction. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Gadolinium sheet converter for neutron radiography

    Energy Technology Data Exchange (ETDEWEB)

    Lima, C.T.S. [Laboratorio de Neutrongrafia em Tempo Real (LNRTR/PEN/COPPE), Universidade Federal do Rio de Janeiro, Ilha do Fundao, Caixa Postal 68509, 21941-972 Rio de Janeiro, RJ (Brazil); Crispim, V.R. [Laboratorio de Neutrongrafia em Tempo Real (LNRTR/PEN/COPPE), Universidade Federal do Rio de Janeiro, Ilha do Fundao, Caixa Postal 68509, 21941-972 Rio de Janeiro, RJ (Brazil); PEN/COPPE-DNC/Escola Politecnica CT, Universidade Federal do Rio de Janeiro, Ilha do Fundao, Caixa Postal 68509, 21941-972 Rio de Janeiro, RJ (Brazil)], E-mail: verginia@con.ufrj.br; Santos, W.M.S. [Laboratorio de Colisao Atomica e Molecular (LACAM/IF), Universidade Federal do Rio de Janeiro, Ilha do Fundao, Caixa Postal 68528, 21941-972 Rio de Janeiro, RJ (Brazil)

    2007-12-15

    This work describes a methodology developed for the confection of gadolinium sheet converter for neutron radiography using the gadolinium chloride (GdCl{sub 3}) as material converter. Though manufactured at a relatively low cost, they are as good as the sheet converter on the market. Here, we present neutron radiography of the penetrameter, the edge spread function, the modulation transfer function and characteristic curves for each set sheet-AA400 Kodak film.

  18. Mars's magnetotail: Nature's current sheet laboratory

    Science.gov (United States)

    Artemyev, A. V.; Angelopoulos, V.; Halekas, J. S.; Runov, A.; Zelenyi, L. M.; McFadden, J. P.

    2017-05-01

    The configuration and stability of an important kinetic plasma structure, the current sheet, determine the efficiency of magnetic energy storage, release, and transport in surrounding plasmas. These properties depend on β (the ratio of plasma pressures to magnetic field pressures) and Mach number M (the ratio of bulk velocities to magnetosonic velocities). For the most investigated current sheet, the near-Earth magnetotail current sheet, these parameters fall within a relatively narrow range of values (high β, low M). To investigate current sheet behavior for a wider range of parameters, we explore current sheets in the magnetotail of Mars using Mars Atmosphere and Volatile Evolution (MAVEN) mission observations. We find that low-β, high-M current sheets are abundant in Mars's magnetotail, but high-β, low-M current sheets can also be found there. Low-β current sheets are nearly force-free, whereas high-M current sheets are balanced by a plasma flow gradient along the tail. We compare current sheet distributions in a (β,M) space for the Martian magnetotail, the near-Earth magnetotail (using Time History of Events and Macroscale Interactions during Substorms (THEMIS) mission), and the distant magnetotail (using Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun (ARTEMIS) mission). We also find that the pressure balance in the Martian magnetotail current sheet can occur by contributions from a wide range of ion species, or, in low beta cases, from field-aligned currents generation of a force-free magnetic field configuration. The Martian magnetotail is a natural laboratory where current sheet of various types can be found and investigated.

  19. The fate of the Greenland Ice Sheet in a geoengineered, high CO2 world

    Science.gov (United States)

    Irvine, Peter J.; Lunt, Daniel J.; Stone, Emma J.; Ridgwell, Andy

    2009-10-01

    Solar radiation management (SRM) geoengineering has been proposed as one means of helping avoid the occurrence of dangerous climate change and undesirable state transitions ('tipping points') in the Earth system. The irreversible melting of the Greenland Ice Sheet is a case in point—a state transition that could occur as a result of CO2-driven elevated global temperatures, and one leading to potentially catastrophic sea-level rise. SRM schemes such as the creation of a 'sunshade' or injection of sulfate aerosols into the stratosphere could reduce incoming solar radiation, and in theory balance, in a global mean, the greenhouse warming resulting from elevated concentrations of CO2 in the atmosphere. Previous work has highlighted that a geoengineered world would have: warming towards the poles, cooling in the tropics, and a reduction in the global hydrological cycle, which may have important implications for the Greenland Ice Sheet. Using a fully coupled global climate model in conjunction with an ice sheet model, we assess the consequences for the mass balance of the Greenland Ice Sheet of the reorganization of climate patterns by the combination of high CO2 and geoengineering. We find that Greenland surface temperature and precipitation anomalies, compared to the pre-industrial situation, decrease almost linearly with increasing levels of SRM geoengineering, but that these combine to create a highly non-linear response of the ice sheet. The substantial melting of the Greenland Ice Sheet predicted for four times pre-industrial CO2 levels is prevented in our model with only a partial application of SRM, and hence without having to fully restore the global average temperature back to pre-industrial levels. This suggests that the degree of SRM geoengineering required to mitigate the worst impacts of greenhouse warming, such as sea-level rise, need not be as extensive as generally assumed.

  20. The fate of the Greenland Ice Sheet in a geoengineered, high CO2 world

    International Nuclear Information System (INIS)

    Irvine, Peter J; Lunt, Daniel J; Stone, Emma J; Ridgwell, Andy

    2009-01-01

    Solar radiation management (SRM) geoengineering has been proposed as one means of helping avoid the occurrence of dangerous climate change and undesirable state transitions ('tipping points') in the Earth system. The irreversible melting of the Greenland Ice Sheet is a case in point-a state transition that could occur as a result of CO 2 -driven elevated global temperatures, and one leading to potentially catastrophic sea-level rise. SRM schemes such as the creation of a 'sunshade' or injection of sulfate aerosols into the stratosphere could reduce incoming solar radiation, and in theory balance, in a global mean, the greenhouse warming resulting from elevated concentrations of CO 2 in the atmosphere. Previous work has highlighted that a geoengineered world would have: warming towards the poles, cooling in the tropics, and a reduction in the global hydrological cycle, which may have important implications for the Greenland Ice Sheet. Using a fully coupled global climate model in conjunction with an ice sheet model, we assess the consequences for the mass balance of the Greenland Ice Sheet of the reorganization of climate patterns by the combination of high CO 2 and geoengineering. We find that Greenland surface temperature and precipitation anomalies, compared to the pre-industrial situation, decrease almost linearly with increasing levels of SRM geoengineering, but that these combine to create a highly non-linear response of the ice sheet. The substantial melting of the Greenland Ice Sheet predicted for four times pre-industrial CO 2 levels is prevented in our model with only a partial application of SRM, and hence without having to fully restore the global average temperature back to pre-industrial levels. This suggests that the degree of SRM geoengineering required to mitigate the worst impacts of greenhouse warming, such as sea-level rise, need not be as extensive as generally assumed.

  1. Shape Optimization of Swimming Sheets

    Energy Technology Data Exchange (ETDEWEB)

    Wilkening, J.; Hosoi, A.E.

    2005-03-01

    The swimming behavior of a flexible sheet which moves by propagating deformation waves along its body was first studied by G. I. Taylor in 1951. In addition to being of theoretical interest, this problem serves as a useful model of the locomotion of gastropods and various micro-organisms. Although the mechanics of swimming via wave propagation has been studied extensively, relatively little work has been done to define or describe optimal swimming by this mechanism.We carry out this objective for a sheet that is separated from a rigid substrate by a thin film of viscous Newtonian fluid. Using a lubrication approximation to model the dynamics, we derive the relevant Euler-Lagrange equations to optimize swimming speed and efficiency. The optimization equations are solved numerically using two different schemes: a limited memory BFGS method that uses cubic splines to represent the wave profile, and a multi-shooting Runge-Kutta approach that uses the Levenberg-Marquardt method to vary the parameters of the equations until the constraints are satisfied. The former approach is less efficient but generalizes nicely to the non-lubrication setting. For each optimization problem we obtain a one parameter family of solutions that becomes singular in a self-similar fashion as the parameter approaches a critical value. We explore the validity of the lubrication approximation near this singular limit by monitoring higher order corrections to the zeroth order theory and by comparing the results with finite element solutions of the full Stokes equations.

  2. Magnetic properties of sheet silicates

    International Nuclear Information System (INIS)

    Ballet, O.; Coey, J.M.D.

    1982-01-01

    Susceptibility, magnetisation and Moessbauer measurements are reported for a representative selection of 2:1 layer phyllosilicates. Eight samples from the mica, vermiculite and smectite groups include examples diluted in iron which are paramagnetic at all temperatures, as well as iron-rich silicates which order magnetically below 10 K. Anisotropic susceptibility of crystals of muscovite, biotite and vermiculite is quantitatively explained with a model where the Fe 2+ ions lie in sites of effective trigonal symmetry, the trigonal axis lying normal to the sheets. The ferrous ground state is an orbital singlet. Ferric iron gives an isotropic contribution to the susceptibility. Fe 2+ -Fe 2+ exchange interactions are ferromagnetic with Gapprox. equal to2 K, whereas Fe 3+ -Fe 3+ coupling is antiferromagnetic in the purely ferric minerals. A positive paramagnetic Curie temperature for glauconite may be attributable to Fe 2+ → Fe 3+ charge transfer. Magnetic order was found to set in inhomogeneously for glauconite at 1-7 K. One biotite sample showed an antiferromagnetic transition at Tsub(N) = 7 K marked by a well-defined susceptibility maximum. Its magnetic structure, consisting of ferromagnetic sheets with moments in their planes coupled antiferromagnetically by other, weak interactions, resembles that found earlier for the 1:1 mineral greenalite. (orig.)

  3. Light Sheet Fluorescence Microscopy (LSFM).

    Science.gov (United States)

    Adams, Michael W; Loftus, Andrew F; Dunn, Sarah E; Joens, Matthew S; Fitzpatrick, James A J

    2015-01-05

    The development of confocal microscopy techniques introduced the ability to optically section fluorescent samples in the axial dimension, perpendicular to the image plane. These approaches, via the placement of a pinhole in the conjugate image plane, provided superior resolution in the axial (z) dimension resulting in nearly isotropic optical sections. However, increased axial resolution, via pinhole optics, comes at the cost of both speed and excitation efficiency. Light sheet fluorescent microscopy (LSFM), a century-old idea made possible with modern developments in both excitation and detection optics, provides sub-cellular resolution and optical sectioning capabilities without compromising speed or excitation efficiency. Over the past decade, several variations of LSFM have been implemented each with its own benefits and deficiencies. Here we discuss LSFM fundamentals and outline the basic principles of several major light-sheet-based imaging modalities (SPIM, inverted SPIM, multi-view SPIM, Bessel beam SPIM, and stimulated emission depletion SPIM) while considering their biological relevance in terms of intrusiveness, temporal resolution, and sample requirements. Copyright © 2015 John Wiley & Sons, Inc.

  4. Separation of sheet flow on the surface of a circular cylinder

    Science.gov (United States)

    Isshiki, Hiroshi; Yoon, Bum-Sang; Yum, Deuk-Joon

    2009-08-01

    The shape of a spout of a pot is very important for the liquid to flow smoothly from the pot. This is known as the "teapot effect." Separation of flow must take place at the tip of the spout. Separation of sheet flow on the surface of a circular cylinder may provide an explanation as to why pot spouts have such a unique shape. As can be easily observed by a simple experiment, separation of sheet flow from the surface of a circular cylinder is a very interesting phenomenon beyond intuition. In the nonviscous case, the flow released at the top of the surface may proceed completely around the surface and come back to the flow start point without separation. In the present paper, effects of gravity and viscosity on sheet flow are theoretically explained and the theory is verified by experiments. The results of the theoretical model proposed in the present study were very similar to the experimental measurements. In the present study, the effects of viscosity on sheet flow on a circular cylinder, the location of flow separation, and other associated responses were investigated.

  5. Thermal rupture of a free liquid sheet

    Science.gov (United States)

    Kitavtsev, G.; Fontelos, M. A.; Eggers, J.

    2018-04-01

    We consider a free liquid sheet, taking into account the dependence of surface tension on temperature, or concentration of some pollutant. The sheet dynamics are described within a long-wavelength description. In the presence of viscosity, local thinning of the sheet is driven by a strong temperature gradient across the pinch region, resembling a shock. As a result, for long times the sheet thins exponentially, leading to breakup. We describe the quasi one-dimensional thickness, velocity, and temperature profiles in the pinch region in terms of similarity solutions, which posses a universal structure. Our analytical description agrees quantitatively with numerical simulations.

  6. Use Medicines Safely

    Science.gov (United States)

    ... Medicines Safely Print This Topic En español Use Medicines Safely Browse Sections The Basics Overview Prescription Medicines ... Medicines 1 of 7 sections The Basics: Prescription Medicines There are different types of medicine. The 2 ...

  7. Turbine-blade tip clearance and tip timing measurements using an optical fiber bundle sensor

    Science.gov (United States)

    Garcia, Iker; Beloki, Josu; Zubia, Joseba; Durana, Gaizka; Aldabaldetreku, Gotzon

    2013-04-01

    Traditional limitations of capacitive, inductive or discharging probe sensor for tip timing and tip clearance measurements are overcome by reflective intensity modulated optical fiber sensors. This paper presents the signals and results corresponding to a one stage turbine rig which rotor has 146 blades, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on turbine casing. It is composed of a central illuminating fiber that guides the light from a laser to the turbine blade, and two concentric rings of receiving fibers that collect the reflected light. Two photodetectors turn this reflected light signal from the receiving rings into voltage. The electrical signals are acquired and saved by a high-sample-rate oscilloscope. In tip clearance calculations the ratio of the signals provided by each ring of receiving fibers is evaluated and translated into distance. In the case of tip timing measurements, only one of the signals is considered to get the arrival time of the blade. The differences between the real and theoretical arrival times of the blades are used to obtain the deflections amplitude. The system provides the travelling wave spectrum, which presents the average vibration amplitude of the blades at a certain nodal diameter. The reliability of the results in the turbine rig testing facilities suggests the possibility of performing these measurements in real turbines under real working conditions.

  8. Quantification of tip-broadening in non-contact atomic force microscopy with carbon nanotube tips

    DEFF Research Database (Denmark)

    Meinander, Kristoffer; Jensen, Thomas N.; Simonsen, Soren B.

    2012-01-01

    Carbon nanotube terminated atomic force microscopy (AFM) probes have been used for the imaging of 5 nm wide surface supported Pt nanoclusters by non-contact (dynamic mode) AFM in an ultra-high vacuum. The results are compared to AFM measurements done with conventional Si-tips, as well...

  9. Tipping point analysis of ocean acoustic noise

    Science.gov (United States)

    Livina, Valerie N.; Brouwer, Albert; Harris, Peter; Wang, Lian; Sotirakopoulos, Kostas; Robinson, Stephen

    2018-02-01

    We apply tipping point analysis to a large record of ocean acoustic data to identify the main components of the acoustic dynamical system and study possible bifurcations and transitions of the system. The analysis is based on a statistical physics framework with stochastic modelling, where we represent the observed data as a composition of deterministic and stochastic components estimated from the data using time-series techniques. We analyse long-term and seasonal trends, system states and acoustic fluctuations to reconstruct a one-dimensional stochastic equation to approximate the acoustic dynamical system. We apply potential analysis to acoustic fluctuations and detect several changes in the system states in the past 14 years. These are most likely caused by climatic phenomena. We analyse trends in sound pressure level within different frequency bands and hypothesize a possible anthropogenic impact on the acoustic environment. The tipping point analysis framework provides insight into the structure of the acoustic data and helps identify its dynamic phenomena, correctly reproducing the probability distribution and scaling properties (power-law correlations) of the time series.

  10. Ten tips for authors of scientific articles.

    Science.gov (United States)

    Hong, Sung-Tae

    2014-08-01

    Writing a good quality scientific article takes experience and skill. I propose 'Ten Tips' that may help to improve the quality of manuscripts for scholarly journals. It is advisable to draft first version of manuscript and revise it repeatedly for consistency and accuracy of the writing. During the drafting and revising the following tips can be considered: 1) focus on design to have proper content, conclusion, points compliant with scope of the target journal, appropriate authors and contributors list, and relevant references from widely visible sources; 2) format the manuscript in accordance with instructions to authors of the target journal; 3) ensure consistency and logical flow of ideas and scientific facts; 4) provide scientific confidence; 5) make your story interesting for your readers; 6) write up short, simple and attractive sentences; 7) bear in mind that properly composed and reflective titles increase chances of attracting more readers; 8) do not forget that well-structured and readable abstracts improve citability of your publications; 9) when revising adhere to the rule of 'First and Last' - open your text with topic paragraph and close it with resolution paragraph; 10) use connecting words linking sentences within a paragraph by repeating relevant keywords.

  11. Aperiodicity Correction for Rotor Tip Vortex Measurements

    Science.gov (United States)

    Ramasamy, Manikandan; Paetzel, Ryan; Bhagwat, Mahendra J.

    2011-01-01

    The initial roll-up of a tip vortex trailing from a model-scale, hovering rotor was measured using particle image velocimetry. The unique feature of the measurements was that a microscope was attached to the camera to allow much higher spatial resolution than hitherto possible. This also posed some unique challenges. In particular, the existing methodologies to correct for aperiodicity in the tip vortex locations could not be easily extended to the present measurements. The difficulty stemmed from the inability to accurately determine the vortex center, which is a prerequisite for the correction procedure. A new method is proposed for determining the vortex center, as well as the vortex core properties, using a least-squares fit approach. This approach has the obvious advantage that the properties are derived from not just a few points near the vortex core, but from a much larger area of flow measurements. Results clearly demonstrate the advantage in the form of reduced variation in the estimated core properties, and also the self-consistent results obtained using three different aperiodicity correction methods.

  12. Tipping point analysis of ocean acoustic noise

    Directory of Open Access Journals (Sweden)

    V. N. Livina

    2018-02-01

    Full Text Available We apply tipping point analysis to a large record of ocean acoustic data to identify the main components of the acoustic dynamical system and study possible bifurcations and transitions of the system. The analysis is based on a statistical physics framework with stochastic modelling, where we represent the observed data as a composition of deterministic and stochastic components estimated from the data using time-series techniques. We analyse long-term and seasonal trends, system states and acoustic fluctuations to reconstruct a one-dimensional stochastic equation to approximate the acoustic dynamical system. We apply potential analysis to acoustic fluctuations and detect several changes in the system states in the past 14 years. These are most likely caused by climatic phenomena. We analyse trends in sound pressure level within different frequency bands and hypothesize a possible anthropogenic impact on the acoustic environment. The tipping point analysis framework provides insight into the structure of the acoustic data and helps identify its dynamic phenomena, correctly reproducing the probability distribution and scaling properties (power-law correlations of the time series.

  13. Effects of plastic anisotropy on crack-tip behaviour

    DEFF Research Database (Denmark)

    Legarth, Brian Nyvang; Tvergaard, Viggo; Kuroda, Mitsutoshi

    2002-01-01

    For a crack in a homogeneous material the effect of plastic anisotropy on crack-tip blunting and on the near-tip stress and strain fields is analyzed numerically. The full finite strain analyses are carried out for plane strain under small scale yielding conditions, with purely symmetric mode I...... loading remote from the crack-tip. In cases where the principal axes of the anisotropy are inclined to the plane of the crack it is found that the plastic zones as well as the stress and strain fields just around the blunted tip of the crack become non-symmetric. In these cases the peak strain...... on the blunted tip occurs off the center line of the crack, thus indicating that the crack may want to grow in a different direction. When the anisotropic axes are parallel to the crack symmetry is retained, but the plastic zones and the near-tip fields still differ from those predicted by standard isotropic...

  14. Dynamic of cold-atom tips in anharmonic potentials

    Science.gov (United States)

    Menold, Tobias; Federsel, Peter; Rogulj, Carola; Hölscher, Hendrik; Fortágh, József

    2016-01-01

    Background: Understanding the dynamics of ultracold quantum gases in an anharmonic potential is essential for applications in the new field of cold-atom scanning probe microscopy. Therein, cold atomic ensembles are used as sensitive probe tips to investigate nanostructured surfaces and surface-near potentials, which typically cause anharmonic tip motion. Results: Besides a theoretical description of this anharmonic tip motion, we introduce a novel method for detecting the cold-atom tip dynamics in situ and real time. In agreement with theory, the first measurements show that particle interactions and anharmonic motion have a significant impact on the tip dynamics. Conclusion: Our findings will be crucial for the realization of high-sensitivity force spectroscopy with cold-atom tips and could possibly allow for the development of advanced spectroscopic techniques such as Q-control. PMID:28144505

  15. Embolization with the Amplatzer Vascular Plug in TIPS Patients

    International Nuclear Information System (INIS)

    Pattynama, Peter M. T.; Wils, Alexandra; Linden, Edwin van der; Dijk, Lukas C. van

    2007-01-01

    Vessel embolization can be a valuable adjunct procedure in transjugular intrahepatic portosystemic shunt (TIPS). During the creation of a TIPS, embolization of portal vein collaterals supplying esophageal varices may lower the risk of secondary rebleeding. And after creation of a TIPS, closure of the TIPS itself may be indicated if the resulting hepatic encephalopathy severely impairs mental functioning. The Amplatzer Vascular Plug (AVP; AGA Medical, Golden Valley, MN) is well suited for embolization of large-diameter vessels and has been employed in a variety of vascular lesions including congenital arteriovenous shunts. Here we describe the use of the AVP in the context of TIPS to embolize portal vein collaterals (n = 8) or to occlude the TIPS (n = 2)

  16. Temperature-controlled irrigated tip radiofrequency catheter ablation

    DEFF Research Database (Denmark)

    Petersen, H H; Chen, X; Pietersen, Adrian

    1998-01-01

    INTRODUCTION: In patients with ventricular tachycardias due to structural heart disease, catheter ablation cures radiofrequency ablation. Irrigated tip radiofrequency ablation using power control and high infusion rates enlarges lesion......: We conclude that temperature-controlled radiofrequency ablation with irrigated tip catheters using low target temperature and low infusion rate enlarges lesion size without increasing the incidence of cratering and reduces coagulum formation of the tip....

  17. Building a hair: tip growth in Arabidopsis thaliana root hairs.

    OpenAIRE

    Carol, Rachel J; Dolan, Liam

    2002-01-01

    The Arabidopsis thaliana root hair is used as a model for studying tip growth in plants. We review recent advances, made using physiological and genetic approaches, which give rise to different, yet compatible, current views of the establishment and maintenance of tip growth in epidermal cells. For example, an active calcium influx channel localized at the tip of Arabidopsis root hairs has been identified by patch-clamp measurements. Actin has been visualized in vivo in Arabidopsis root hairs...

  18. DO SLOVENIAN DEALERS USE TECHNIQUES FOR INCREASING THEIR TIPS?

    Directory of Open Access Journals (Sweden)

    Andrej Raspor

    2016-05-01

    Full Text Available In 1996 Michael Lynn introduced the idea that restaurant managers could increase tips for their waiters and thus increase turnover by training the waiters to engage tip-enhancing behaviours. Since then, the list of tip-enhancing behaviours has expanded. Therefore the potential to increase tips is more accessible. The purpose of this paper was to examine how Slovenian dealers use strategies to increase their tips. We tested fourteen techniques to increase tips. The study was carried out among 473 gaming employees, 279 of which are dealers, in the Slovenian gaming industry, in order to find out how they use these techniques and which of them can bring about an increase in their tips. The study showed that Slovenian dealers mostly do not use these techniques, and that the dealers who do use them tend to receive tips more often. The findings imply that managers and employees should be informed of these techniques in order to increase tips and their overall income. Practical implications are that we suggest that management considers these ideas for increasing flexibility and reducing the cost of work: (1 informing dealers on ways of increasing tips, (2 including the acquisition of this specific knowledge in their career plans, (3 carrying out a reform of the reward system which would include tips. Social implications will be shown in a higher gaming revenue. It is very likely – as shown in our research – that employees will receive higher wages as these will be topped up by tips. The state, in turn, will collect more taxes.

  19. Numerical modelling of unsteady 2D sheet cavitation

    NARCIS (Netherlands)

    de Lange, D.F.; de Bruin, G.J.; van Wijngaarden, L.; van Wijngaarden, L.

    1996-01-01

    Unsteady 2D sheet cavitation has been calculated by a BEM. Cubics are used to represent various quantities like the potential on the wet part of the profile, the normal velocity on the sheet, the geometry of the profile and the sheet. The growing cavity sheet, the re-entrant jet and the sheet

  20. Poisoning Safety Fact Sheet (2015)

    Science.gov (United States)

    ... and Control Website. Unintentional poisoning fatalities and nonfatal injuries, children ages 19 and under. Available from: http: / / www. cdc. gov/ injury/ wisqars/ . Accessed February 23, ... In-Depth Look at Keeping Young Children Safe Around Medicine. Washington, DC: Safe Kids Worldwide, ...

  1. Energy Savers Tips on Saving Energy& Money at Home

    Energy Technology Data Exchange (ETDEWEB)

    2003-06-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances

  2. Is a Drain Tip Culture Required After Spinal Surgery?

    Science.gov (United States)

    Kobayashi, Kazuyoshi; Imagama, Shiro; Ito, Zenya; Ando, Kei; Yagi, Hideki; Hida, Tetsuro; Ito, Kenyu; Ishikawa, Yoshimoto; Tsushima, Mikito; Ishiguro, Naoki

    2017-10-01

    The efficacy of use of a drain tip culture for early detection of surgical-site infection (SSI) was investigated in 329 patients after spinal surgery. To examine the efficacy of a wound drain tip culture for detection of SSI in spinal surgery. A complication of SSI after spinal surgery has high associated morbidity and mortality, and is often difficult to treat. The subjects were patients who underwent spinal surgery at our institution between January 2010 and March 2013. All subjects were treated with antimicrobial prophylaxis based on evidence-based guidelines and were followed for at least 6 months after surgery. Data from culture studies using the distal tip of the wound drain were used for analysis. Drain tip cultures were positive in 34 cases and there were 19 SSIs. Ten of the 34-tip culture-positive wounds developed SSI. Drain tip cultures had a sensitivity of 52%, specificity of 92%, positive predictive value (PPV) of 29%, and negative predictive value of 97% for predicting a wound infection. The association between a positive suction tip culture and wound infection was significant (P<0.05). The PPV for SSI was 60% in cases in which methicillin-resistant bacteria were detected in a drain tip, and the SSI rate in these cases differed significantly compared with those with non-methicillin-resistant bacteria (P=0.01). A drain tip culture is useful for early detection of SSI caused by methicillin-resistant bacteria.

  3. Microneedles array with biodegradable tips for transdermal drug delivery

    Science.gov (United States)

    Iliescu, Ciprian; Chen, Bangtao; Wei, Jiashen; Tay, Francis E. H.

    2008-12-01

    The paper presented an enhancement solution for transdermal drug delivery using microneedles array with biodegradable tips. The microneedles array was fabricated by using deep reactive ion etching (DRIE) and the biodegradable tips were made to be porous by electrochemical etching process. The porous silicon microneedle tips can greatly enhance the transdermal drug delivery in a minimum invasion, painless, and convenient manner, at the same time; they are breakable and biodegradable. Basically, the main problem of the silicon microneedles consists of broken microneedles tips during the insertion. The solution proposed is to fabricate the microneedle tip from a biodegradable material - porous silicon. The silicon microneedles are fabricated using DRIE notching effect of reflected charges on mask. The process overcomes the difficulty in the undercut control of the tips during the classical isotropic silicon etching process. When the silicon tips were formed, the porous tips were then generated using a classical electrochemical anodization process in MeCN/HF/H2O solution. The paper presents the experimental results of in vitro release of calcein and BSA with animal skins using a microneedle array with biodegradable tips. Compared to the transdermal drug delivery without any enhancer, the microneedle array had presented significant enhancement of drug release.

  4. Terahertz Nanofocusing with Cantilevered Terahertz-Resonant Antenna Tips.

    Science.gov (United States)

    Mastel, Stefan; Lundeberg, Mark B; Alonso-González, Pablo; Gao, Yuanda; Watanabe, Kenji; Taniguchi, Takashi; Hone, James; Koppens, Frank H L; Nikitin, Alexey Y; Hillenbrand, Rainer

    2017-11-08

    We developed THz-resonant scanning probe tips, yielding strongly enhanced and nanoscale confined THz near fields at their tip apex. The tips with length in the order of the THz wavelength (λ = 96.5 μm) were fabricated by focused ion beam (FIB) machining and attached to standard atomic force microscopy (AFM) cantilevers. Measurements of the near-field intensity at the very tip apex (25 nm radius) as a function of tip length, via graphene-based (thermoelectric) near-field detection, indicate their first and second order geometrical antenna resonances for tip length of 33 and 78 μm, respectively. On resonance, we find that the near-field intensity is enhanced by one order of magnitude compared to tips of 17 μm length (standard AFM tip length), which is corroborated by numerical simulations that further predict remarkable intensity enhancements of about 10 7 relative to the incident field. Because of the strong field enhancement and standard AFM operation of our tips, we envision manifold and straightforward future application in scattering-type THz near-field nanoscopy and THz photocurrent nanoimaging, nanoscale nonlinear THz imaging, or nanoscale control and manipulation of matter employing ultrastrong and ultrashort THz pulses.

  5. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  6. Dependence of electric field on STM tip preparation

    DEFF Research Database (Denmark)

    Huang, D.H.; Grey, Francois; Aono, M.

    1998-01-01

    Voltage pulses applied between an STM tip and a surface can modify the surface on the nanometer scale due to electric-field-induced evaporation. However, at present, different groups have achieved surface modification with quite different bias conditions, and it is still difficult to obtain high...... reproducibility in such experiments. In this paper, we measure the tip displacement during a pulse at constant tunnelling current, and deduce that the electric field produced by the pulse depends in a systematic way on tip preparation, The results show how differences in tip preparation can be a major source...

  7. Energy Saver: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  8. Wettability of AFM tip influences the profile of interfacial nanobubbles

    Science.gov (United States)

    Teshima, Hideaki; Takahashi, Koji; Takata, Yasuyuki; Nishiyama, Takashi

    2018-02-01

    To accurately characterize the shape of interfacial nanobubbles using atomic force microscopy (AFM), we investigated the effect of wettability of the AFM tip while operating in the peak force tapping (PFT) mode. The AFM tips were made hydrophobic and hydrophilic by Teflon AF coating and oxygen plasma treatment, respectively. It was found that the measured base radius of nanobubbles differed between AFM height images and adhesion images, and that this difference depended on the tip wettability. The force curves obtained during the measurements were also different depending on the wettability, especially in the range of the tip/nanobubble interaction and in the magnitude of the maximum attractive force in the retraction period. The difference suggests that hydrophobic tips penetrate the gas/liquid interface of the nanobubbles, with the three phase contact line being pinned on the tip surface; hydrophilic tips on the other hand do not penetrate the interface. We then quantitatively estimated the pinning position and recalculated the true profiles of the nanobubbles by comparing the height images and adhesion images. As the AFM tip was made more hydrophilic, the penetration depth decreased and eventually approached zero. This result suggests that the PFT measurement using a hydrophilic tip is vital for the acquisition of reliable nanobubble profiles.

  9. On open and closed tips of bunsen burner flames

    Science.gov (United States)

    Kozlovsky, G.; Sivashinsky, G. I.

    1994-04-01

    An adiabatic, constant-density reaction-diffusion-advection model for the Bunsen burner flame tip is studied numerically. It is shown that for Lewis numbers exceeding unity the reaction rate and flame speed gradually increase toward the flame tip. For small Lewis numbers the picture is quite different. The reaction rate drops near the tip. In spite of this the flame survives and, moreover, manages to consume all the fuel supplied to the reaction zone. There is no leakage of the fuel through the front. The flame speed varies nonmonotonously along the front from gradual reduction to steep increase near the tip.

  10. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-05-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  11. Alternative Medicine

    Science.gov (United States)

    ... valid therapies, delaying proven treatment for serious conditions. Holistic Treatments Holistic medicine is a system of health care ... techniques including meditation, biofeedback and relaxation training. While holistic treatments can be part of a good physical regimen, ...

  12. TOMATOES BALANCE SHEET IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Dragoş Mihai MEDELETE

    2013-01-01

    Full Text Available Tomatoes are one of the most representative vegetable species cultivated in our country. This allegation is based on the essential elements of tomatoes culture respectively area cultivated, total production and average yield per hectare - indicators for 2007-2009 reached average levels of 48.8 thousand hectares and 736.9 thousand tonnes respectively 15101kg / ha. Presentation of food helps establish balance of the demand and supply component parts total as follows: production, imports, exports (on request food consumption and losses (on request. It is worth noting that in Romania, unlike global and continental do not appear reports for stocks, industrial raw materials, feed consumption, and other uses. Based on the total volume of supply and demand it could be determining the national balance sheet for the product.

  13. TIPS Placement in Swine, Guided by Electromagnetic Real-Time Needle Tip Localization Displayed on Previously Acquired 3-D CT

    International Nuclear Information System (INIS)

    Solomon, Stephen B.; Magee, Carolyn; Acker, David E.; Venbrux, Anthony C.

    1999-01-01

    Purpose: To determine the feasibility of guiding a transjugular intrahepatic portosystemic shunt (TIPS) procedure with an electromagnetic real-time needle tip position sensor coupled to previously acquired 3-dimensional (3-D) computed tomography (CT) images. Methods: An electromagnetic position sensor was placed at the tip of a Colapinto needle. The real-time position and orientation of the needle tip was then displayed on previously acquired 3-D CT images which were registered with the five swine. Portal vein puncture was then attempted in all animals. Results: The computer calculated accuracy of the position sensor was on average 3 mm. Four of five portal vein punctures were successful. In the successes, only one or two attempts were necessary and success was achieved in minutes. Conclusion: A real-time position sensor attached to the tip of a Colapinto needle and coupled to previously acquired 3-D CT images may potentially aid in entering the portal vein during the TIPS procedure

  14. Nuclear medicine

    International Nuclear Information System (INIS)

    Chamberlain, M.J.

    1986-01-01

    Despite an aggressive, competitive diagnostic radiology department, the University Hospital, London, Ontario has seen a decline of 11% total (in vivo and in the laboratory) in the nuclear medicine workload between 1982 and 1985. The decline of in vivo work alone was 24%. This trend has already been noted in the U.S.. Nuclear medicine is no longer 'a large volume prosperous specialty of wide diagnostic application'

  15. Nuclear medicine

    International Nuclear Information System (INIS)

    Blanquet, Paul; Blanc, Daniel.

    1976-01-01

    The applications of radioisotopes in medical diagnostics are briefly reviewed. Each organ system is considered and the Nuclear medicine procedures pertinent to that system are discussed. This includes, the principle of the test, the detector and the radiopharmaceutical used, the procedure followed and the clinical results obtained. The various types of radiation detectors presently employed in Nuclear Medicine are surveyed, including scanners, gamma cameras, positron cameras and procedures for obtaining tomographic presentation of radionuclide distributions [fr

  16. Fact Sheets on Pesticides in Schools.

    Science.gov (United States)

    National Coalition against the Misuse of Pesticides, Washington, DC.

    This document consists of a collection of fact sheets about the use of pesticides in schools and how to reduce it. The sheets are: (1) "Alternatives to Using Pesticides in Schools: What Is Integrated Pest Management?"; (2) "Health Effects of 48 Commonly Used Pesticides in Schools"; (3) "The Schooling of State Pesticide…

  17. Advanced friction modeling in sheet metal forming

    NARCIS (Netherlands)

    Hol, J.; Cid Alfaro, M.V.; Meinders, Vincent T.; Huetink, Han

    2011-01-01

    The Coulomb friction model is frequently used for sheet metal forming simulations. This model incorporates a constant coefficient of friction and does not take the influence of important parameters such as contact pressure or deformation of the sheet material into account. This article presents a

  18. Steel Sheet Pile Walls in Soft Soil

    NARCIS (Netherlands)

    Kort, D.A.

    2002-01-01

    For almost a century, steel sheet pile walls are applied worldwide as earth retaining structures for excavations and quay walls. Within the framework of the development of European structural codes for Civil Engineering works, the Eurocodes, Eurocode 3 Part 5 for design of steel sheet pile walls was

  19. Clouds enhance Greenland ice sheet meltwater runoff

    NARCIS (Netherlands)

    Van Tricht, K.; Lhermitte, S.; Lenaerts, J. T M; Gorodetskaya, I. V.; L'Ecuyer, T. S.; Noël, B.; Van Den Broeke, M. R.; Turner, D. D.; Van Lipzig, N. P M

    2016-01-01

    The Greenland ice sheet has become one of the main contributors to global sea level rise, predominantly through increased meltwater runoff. The main drivers of Greenland ice sheet runoff, however, remain poorly understood. Here we show that clouds enhance meltwater runoff by about one-third relative

  20. Balance velocities of the Greenland ice sheet

    DEFF Research Database (Denmark)

    Joughin, I.; Fahnestock, M.; Ekholm, Simon

    1997-01-01

    We present a map of balance velocities for the Greenland ice sheet. The resolution of the underlying DEM, which was derived primarily from radar altimetery data, yields far greater detail than earlier balance velocity estimates for Greenland. The velocity contours reveal in striking detail......, the balance map is useful for ice-sheet modelling, mass balance studies, and field planning....

  1. Antibubbles and fine cylindrical sheets of air

    NARCIS (Netherlands)

    Beilharz, D.; Guyon, A.; Li, E.Q.; Thoraval, Marie-Jean; Thoroddsen, S.T.

    2015-01-01

    Drops impacting at low velocities onto a pool surface can stretch out thin hemispherical sheets of air between the drop and the pool. These air sheets can remain intact until they reach submicron thicknesses, at which point they rupture to form a myriad of microbubbles. By impacting a

  2. Ranking beta sheet topologies of proteins

    DEFF Research Database (Denmark)

    Fonseca, Rasmus; Helles, Glennie; Winter, Pawel

    2010-01-01

    One of the challenges of protein structure prediction is to identify long-range interactions between amino acids. To reliably predict such interactions, we enumerate, score and rank all beta-topologies (partitions of beta-strands into sheets, orderings of strands within sheets and orientations of...

  3. Nigerian Ethnomedicine and Medicinal Plant Flora: Anti - ulcer ...

    African Journals Online (AJOL)

    Aloe vera is an exotic species that is getting naturalized and commercially cultivated in the area. The pieces of information herein are regarded as useful tips for the bioassay-guided isolation of active principles from local medicinal plants. Key Words: Anti-ulcer, folk remedy, secondary metabolites, saponins, tannins

  4. [Predictable tip suture techniques in rhinoplasty].

    Science.gov (United States)

    Papel, I D

    2010-09-01

    Recontouring the nasal tip in rhinoplastic procedures has generated a wide range of surgical techniques. These range from aggressive cartilage resection, division, grafting, or suture methods. Each of these categories contains many variations described in hundreds of publications. The goal of this communication is to describe a predictable, reproducible technique that can be used in a wide variety of rhinoplasty operations. Based on pre-existing anatomy variations of this technique can be adopted. The author described the basic technique in 2004 [1].The cornerstone of the technique is a predictable method of narrowing the interdomal space utilizing a suture technique. This procedure employs a pair of permanent sutures designed to minimize distortion, valve impingement and overcorrection. It can be performed through intranasal or external approaches. This paper will define the wide interdomal space, describe the technique, and demonstrate the efficacy of the technique in 250 rhinoplasty procedures. In addition, variations of the technique for specific goals will be shown.

  5. Twelve tips for developing an integrated curriculum.

    Science.gov (United States)

    Malik, Alam Sher; Malik, Rukhsana Hussain

    2011-01-01

    Integration of curriculum is meant to make the teaching/learning activities meaningful; however, the interpretation of 'integration' varies in different institutions and among individuals. Many medical schools find it hard to change their existing curriculum or develop a new integrated curriculum mainly because of lack of will, infrastructure and understanding the process of change. Drawn from experience, these 12 tips relating to staff development, establishing working groups, organizing the teaching/learning materials under themes and developing some innovative teaching/learning and assessment strategies, are the techniques that a teaching institution can use to change the existing curriculum to an integrated one or develop a new curriculum. Knowing about the different levels of integration and steps for developing an integrated curriculum can make it easier to integrate an existing curriculum or develop a new one.

  6. Onion root tip cell system for biodosimetry?

    International Nuclear Information System (INIS)

    Paradiz, J; Druskovic, B.; Lovka, M.; Skrk, J.

    1996-01-01

    Methodology for radiation dose assessment based on chromosomal damage to plant cells has no yet been established, although root meristems have been the pioneer cytogenetic materials and profound analyses of irradiated meristematic cells of horse bean (Viciafaba L.) had been performed. Onion (Allium cepa L.) root tips frequently used for radiation cytogenetic studies, are recently considered to be one of the most promising plant test system for the detection of genotoxic environmental pollutants. We studied the possibility of using cytogenetic analyses of irradiated onion cells to determine the effective biological dose of ionizing radiation. The dose-effect relationships for chromosomal damages to onion meristematic cells were established after plants had been irradiated and subsequently grown in both laboratory and field conditions

  7. Noise-compliant tip-shape derivation

    Science.gov (United States)

    Williams, P. M.; Davies, M. C.; Roberts, C. J.; Tendler, S. J. B.

    Wide use of the blind tip-derivation procedure has lead to the realization of the problem of noise in experimental image data. A modification to the algorithm by which the probe shape is extracted from image data is described. By consideration of the possible levels of noise in an image, a realistic estimate of the probe geometry can be derived from unfiltered experimental image data. The new procedure is demonstrated by its application to a test image that has been deliberately degraded through the addition of random noise. The results are compared with those from the current technique. The technique has significant application in metrology through the compensation of both lateral and vertical measurement errors.

  8. Magnetic nondestructive testing of rotor blade tips

    Science.gov (United States)

    Cardelli, E.; Faba, A.; Marsili, R.; Rossi, G.; Tomassini, R.

    2015-05-01

    This paper deals with a particular magnetic nondestructive technique applied to the control of the position of the steel blades in rotating parts of turbines and engines. The working principle is based on a bridge of four identical magneto-resistive sensors. One sensor is placed near the blades, and the change in magnetic field produced by a permanent magnet and deviated by the change in position of the blade is detected by the sensor bridge. The position of the sensor is indicated, via dedicated FEM simulations, in order to have high sensitivity to the position change and high output signal. The accuracy and effectiveness of the proposed method are shown by experimental tests carried out in our laboratories. In particular, the tests indicate that the proposed magnetic nondestructive technique can be used in an almost large velocity range, and for quite different values of blade tip. The method seems also promising for the detection of blade vibrations.

  9. Thulium fiber laser lithotripsy using small spherical distal fiber tips

    Science.gov (United States)

    Wilson, Christopher R.; Hardy, Luke A.; Kennedy, Joshua D.; Irby, Pierce B.; Fried, Nathaniel M.

    2016-02-01

    This study tests a 100-μm-core fiber with 300-μm-diameter ball tip during Thulium fiber laser (TFL) lithotripsy. The TFL was operated at 1908 nm wavelength with 35-mJ pulse energy, 500-μs pulse duration, and 300-Hz pulse rate. Calcium oxalate/phosphate stone samples were weighed, laser procedure times measured, and ablation rates calculated for ball tip fibers, with comparison to bare tip fibers. Photographs of ball tips were taken before and after each procedure to observe ball tip degradation and determine number of procedures completed before need to replace fiber. Saline irrigation rates and ureteroscope deflection were measured with and without TFL fiber present. There was no statistical difference (P > 0.05) between stone ablation rates for single-use ball tip fiber (1.3 +/- 0.4 mg/s) (n=10), multiple-use ball tip fiber (1.3 +/- 0.5 mg/s) (n=44), and conventional single-use bare tip fibers (1.3 +/- 0.2 mg/s) (n=10). Ball tip durability varied widely, but fibers averaged > 4 stone procedures before decline in stone ablation rates due to mechanical damage at front surface of ball tip. The small fiber diameter did not impact ureteroscope deflection or saline flow rates. The miniature ball tip fiber may provide a cost-effective design for safe fiber insertion through the ureteroscope working channel and the ureter without risk of scope damage or tissue perforation, and without compromising stone ablation efficiency during TFL ablation of kidney stones.

  10. Regularization mechanism in blind tip reconstruction procedure

    International Nuclear Information System (INIS)

    Jóźwiak, G.; Henrykowski, A.; Masalska, A.; Gotszalk, T.

    2012-01-01

    In quantitative investigations of mechanical and chemical surface parameters using atomic force microscopy (AFM) techniques the determination of the probe radius and shape is required. To the most favorable methods of the microprobe characterization belongs the blind tip reconstruction method (BTR). The BTR similar to many other inverse problems is sensitive to noise and needs the so-called regularization mechanism. In this article we describe and investigate two the most popular regularization schemes, which were proposed in Villarubia et al. (1997) and Tian et al. (2008) . We have shown that the procedure described in Tian et al. (2008) enables very effective probe shape reconstruction if we know the statistics of noise present in the AFM system. The increase of effectiveness with relation to the procedure described in Villarubia (1997) is so significant that makes it possible to reconstruct probes with much larger resolution. We have also noticed the fact, that probes reconstructed by means of the procedure presented in Tian et al. (2008) have flat apexes for AFM images with low signal to noise ratio (SNR). We propose procedure, which can improve the probe apex reconstruction. It uses the AFM image to estimate the initial shape of the reconstructed probe. This shape may be further improved by the BTR algorithm. We have shown that it is possible only for the procedure described in Tian et al. (2008) . -- Highlights: ► We study regularization mechanism of blind tip reconstruction. ► We propose combination of direct probe imaging with BTR to improve the reconstruction of a probe apex. ► The possibility of improving efficiency of the BTR procedure is presented. ► The possibility of improving resolution of a reconstructed probe is presented.

  11. Folded Sheet Versus Transparent Sheet Models for Human Symmetry Judgments

    Directory of Open Access Journals (Sweden)

    Jacques Ninio

    2011-07-01

    Full Text Available As a contribution to the mysteries of human symmetry perception, reaction time data were collected on the detection of symmetry or repetition violations, in the context of short term visual memory studies. The histograms for reaction time distributions are rather narrow in the case of symmetry judgments. Their analysis was performed in terms of a simple kinetic model of a mental process in two steps, a slow one for the construction of the representation of the images to be compared, and a fast one, in the 50 ms range, for the decision. There was no need for an additional ‘mental rotation’ step. Symmetry seems to facilitate the construction step. I also present here original stimuli showing a color equalization effect across a symmetry axis, and its counterpart in periodic patterns. According to a “folded sheet model”, when a shape is perceived, the brain automatically constructs a mirror-image representation of the shape. Based in part on the reaction time analysis, I present here an alternative “transparent sheet” model in which the brain constructs a single representation, which can be accessed from two sides, thus generating simultaneously a pattern and its mirror-symmetric partner. Filtering processes, implied by current models of symmetry perception could intervene at an early stage, by nucleating the propagation of similar perceptual groupings in the two symmetric images.

  12. Modification of AFM Tips for Facilitating Picking-up of Nanoparticles

    International Nuclear Information System (INIS)

    Peng, Wang; Hai-Jun, Yang; Hua-Bin, Wang; Hai, Li; Xin-Yan, Wang; Ying, Wang; Jun-Hong, Lü; Bin, Li; Yi, Zhang; Jun, Hu

    2008-01-01

    The radius of atomic force microscope (AFM) tip is a key factor that influences nonspecific interactions between AFM tip and nanoparticles. Generally, a tip with larger radius contributes to a higher efficiency of picking up nanoparticles. We provide two methods for modifying the AFM tip: one is to wear a tip apex on a solid substrate and the other is to coat a tip with poly (dimethylsiloxane) (PDMS). Both the approaches can enhance the adhesion force between the tip and nanoparticles by increasing tip radius. The experimental results show that a modified tip, compared to an unmodified one, achieves six-fold efficiency improvement in the capture of targeted colloidal gold nanoparticles. (general)

  13. Tip-leakage cavitation in the clearance of a 2D hydrofoil with fillets: high-speed visualization and PIV/PTV measurements

    Science.gov (United States)

    Zapryagaev, Ivan I.; Timoshevskiy, Mikhail V.; Pervunin, Konstantin S.

    2017-09-01

    Tip-clearance cavitation is one of the most aggressive forms of cavitation as it can cause surface erosion of hydraulic machinery elements and, as a result, their fatigue damage and disturb designed operating conditions. At present, the literature lacks for detailed experimental data on the inception and development of this type of cavitation at various flow conditions. In the paper, a tip-leakage cavitation occurring in the clearance between an end face of a 2D hydrofoil (a scaled-down model of guide vanes (GV) of a Francis turbine) and a transparent wall of the test section was studied. The experiments were carried out for different cavitating regimes on the cavitation number and two attack angles of 3° and 9°, with the gap size (tip clearance width) varied in the range from 0.4 to 0.8 mm. In order to determine the cavitation inception conditions and investigate the dynamics of the tip-leakage cavitation, a high-speed visualization was applied. A modified PIV/PTV technique with a diverging laser beam instead of a laser light sheet was used to measure the mean velocity distributions within the gap. It was shown that the cavitation pattern on the suction side of the GV model impacts the dynamics of the leakage flow in the gap but does not affect the sheet cavity formed close to the foil leading edge in the clearance as well as its size and dynamics. When the gap size is increased, the tip-leakage cavitation initiates at higher cavitation numbers or, in other words, conditions for the cavitation occurrence become more favorable.

  14. Travel medicine

    Science.gov (United States)

    Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

    2014-01-01

    Abstract Objective To define the practice of travel medicine, provide the basics of a comprehensive pretravel consultation for international travelers, and assist in identifying patients who might require referral to travel medicine professionals. Sources of information Guidelines and recommendations on travel medicine and travel-related illnesses by national and international travel health authorities were reviewed. MEDLINE and EMBASE searches for related literature were also performed. Main message Travel medicine is a highly dynamic specialty that focuses on pretravel preventive care. A comprehensive risk assessment for each individual traveler is essential in order to accurately evaluate traveler-, itinerary-, and destination-specific risks, and to advise on the most appropriate risk management interventions to promote health and prevent adverse health outcomes during travel. Vaccinations might also be required and should be personalized according to the individual traveler’s immunization history, travel itinerary, and the amount of time available before departure. Conclusion A traveler’s health and safety depends on a practitioner’s level of expertise in providing pretravel counseling and vaccinations, if required. Those who advise travelers are encouraged to be aware of the extent of this responsibility and to refer all high-risk travelers to travel medicine professionals whenever possible. PMID:25500599

  15. Tubularized Incised Plate (TIP) Urethroplasty: Extended Use in ...

    African Journals Online (AJOL)

    Objective: Recently, tubularized incised plate (TIP) urethroplasty (Snodgrass repair) has gained popularity for the primary repair of distal and proximal hypospadias. This study was carried out to evaluate TIP urethroplasty in the repair of failed and complicated hypospadias cases. Patients and Methods: This study was ...

  16. Times required for cavity preparation using ultrasonic tips

    NARCIS (Netherlands)

    Özcan, Mutlu; Nergiz, Ibrahim; Pfeiffer, Peter; Tütüncü, Rengin

    1999-01-01

    Poster for: Date/Event/Venue: 10.03.99-13.03.99 77th General Session & Exhibition of the IADR Vancouver The purpose of this study was to evaluate the required time for opening the proximal cavities using three ultrasonic tips of different sizes and fine diamond inlay bur followed by ultrasonic tip.

  17. Prevent Tipping Furniture from Injuring or Killing Young Children

    Science.gov (United States)

    ... this! Home » Health Tips » Child Emergencies Prevent Tipping Furniture from Injuring or Killing Young Children The nation’s ... a child — killed by a piece of a furniture, appliance or a television falling on them. “It ...

  18. The cytoskeleton in plant and fungal cell tip growth

    NARCIS (Netherlands)

    Geitmann, A.; Emons, A.M.C.

    2000-01-01

    Tip-growing cells have a particular lifestyle that is characterized by the following features: (1) the cells grow in one direction, forming a cylindrical tube; (2) tip-growing cells are able to penetrate their growth environment, thus having to withstand considerable external forces; (3) the growth

  19. Build Your Child's Vocabulary! Ten Fun and Easy Tips.

    Science.gov (United States)

    1998

    This booklet presents parents with 10 tips for helping their children expand their vocabulary. The 10 tips in the booklet are: read and use context; look for synonyms and antonyms; rhyming and homophones; compound words; look for related words; prefixes and suffixes; word maps; see how words are formed; mine the wealth of other languages; and use…

  20. Numerical simulation of tip clearance impact on a pumpjet propulsor

    Directory of Open Access Journals (Sweden)

    Lin Lu

    2016-05-01

    Full Text Available Numerical simulation based on the Reynolds Averaged Navier–Stokes (RANS Computational Fluid Dynamics (CFD method had been carried out with the commercial code ANSYS CFX. The structured grid and SST k–ω turbulence model had been adopted. The impact of non-condensable gas (NCG on cavitation performance had been introduced into the Schnerr and Sauer cavitation model. The numerical investigation of cavitating flow of marine propeller E779A was carried out with different advance ratios and cavitation numbers to verify the numerical simulation method. Tip clearance effects on the performance of pumpjet propulsor had been investigated. Results showed that the structure and characteristics of the tip leakage vortex and the efficiency of the propulsor dropped more sharply with the increase of the tip clearance size. Furthermore, the numerical simulation of tip clearance cavitation of pumpjet propulsor had been presented with different rotational speed and tip clearance size. The mechanism of tip clearance cavitation causing a further loss of the efficiency had been studied. The influence of rotational speed and tip clearance size on tip clearance cavitation had been investigated.

  1. Ten Timeless Tips for Keeping on Top of Teaching Technology

    Science.gov (United States)

    Poling, Devereaux A.; LoSchiavo, Frank M.

    2014-01-01

    We provide tips for helping psychology faculty effectively seek, select, and place new technology into pedagogical practice. We also provide tips to help psychology departments position themselves for a future that includes teaching technologies that have not yet been created. Instead of discussing today's top innovations in teaching (which…

  2. Disproportionate abundance between ectomycorrhizal root tips and their associated mycelia

    DEFF Research Database (Denmark)

    Kjøller, Rasmus

    2006-01-01

    compared the ectomycorrhizal external mycelial community with the adjacent root-tip community in a Danish beech forest. Sand-filled in-growth mesh bags were used to trap external mycelia by incubating the mesh bags in the soil for 70 days. The adjacent ectomycorrhizal root-tip communities were recorded...

  3. Suture techniques in nasal tip sculpture: current concepts.

    Science.gov (United States)

    Lo, S; Rowe-Jones, J

    2007-08-01

    The three-dimensional anatomy and conspicuous location of the nasal tip makes it one of the most challenging sites of facial plastic surgery. This article reviews literature on nasal tip sculpture using suture techniques, as well as the authors' own experience. A search was conducted using Pubmed, the Google internet search engine and the authors' files, using the keywords 'nasal tip', 'suture', 'rhinoplasty' and 'septorhinoplasty'. Common nasal tip suture techniques and suture algorithms are presented, along with a summary of the indications and side effects of each technique. Predictable long-term results are more likely to occur with minimal local tissue excision. Suture techniques remodel the shape of the nasal tip by altering the configuration of, and the relationship between, the tip cartilages and their supporting structures; they also preserve nasal tip anatomy and limit resection. Intra-operatively, the effects are immediately visible, and can be adjusted or reversed. Tip sutures should therefore be considered instead of tissue excision whenever possible.

  4. Cryopreservation of in vitro -grown shoot tips of apricot ( Prunus ...

    African Journals Online (AJOL)

    In vitro grown apricot (Prunus armeniaca L.) cv. El-Hamawey shoot tips were successfully cryopreserved using an encapsulation-dehydration procedure. Shoot tips were encapsulated in calcium-alginate beads before preculture on woody plant (WP) medium supplemented with different sucrose concentrations; 0.1, 0.3, 0.5, ...

  5. 29 CFR 531.59 - The tip wage credit.

    Science.gov (United States)

    2010-07-01

    ... that an employee who can show to the satisfaction of the Secretary of Labor that the actual amount of... PAYMENTS UNDER THE FAIR LABOR STANDARDS ACT OF 1938 Interpretations Payment of Wages to Tipped Employees..., under the provisions of section 3(m) the amount paid to a tipped employee by an employer is deemed to be...

  6. Restaurant Dining: Seven Tips for Staying Gluten Free

    Science.gov (United States)

    GiG Education Bulletin Restaurant Dining: Seven Tips for Staying Gluten-Free Updated May 2014 Tips for Dining Away from Home 1. Selection of eating establishment. • Your success at gluten-free dining will be determined by a number of factors, including the ...

  7. Anisotropic Adhesion Properties of Triangular-Tip-Shaped Micropillars

    KAUST Repository

    Kwak, Moon Kyu

    2011-06-01

    Directional dry adhesive microstructures consisting of high-density triangular-tip-shaped micropillars are described. The wide-tip structures allow for unique directional shear adhesion properties with respect to the peeling direction, along with relatively high normal adhesion. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Ten Tips to Prevent an Accidental Overdose

    Science.gov (United States)

    ... slices, or tears. Second, once you’re at home, check the label on the inside package to be sure you have the right medicine and that the lid and seal are not broken. Third, check the color, shape, size, and smell. ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging ... the limitations of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch ...

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses ... limitations of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of ...

  11. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...

  12. Children's (Pediatric) Nuclear Medicine

    Science.gov (United States)

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  13. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  15. Ice sheet margins and ice shelves

    Science.gov (United States)

    Thomas, R. H.

    1984-01-01

    The effect of climate warming on the size of ice sheet margins in polar regions is considered. Particular attention is given to the possibility of a rapid response to warming on the order of tens to hundreds of years. It is found that the early response of the polar regions to climate warming would be an increase in the area of summer melt on the ice sheets and ice shelves. For sufficiently large warming (5-10C) the delayed effects would include the breakup of the ice shelves by an increase in ice drainage rates, particularly from the ice sheets. On the basis of published data for periodic changes in the thickness and melting rates of the marine ice sheets and fjord glaciers in Greenland and Antarctica, it is shown that the rate of retreat (or advance) of an ice sheet is primarily determined by: bedrock topography; the basal conditions of the grounded ice sheet; and the ice shelf condition downstream of the grounding line. A program of satellite and ground measurements to monitor the state of ice sheet equilibrium is recommended.

  16. Numerical study of hydrofoil tip vortex fluid field

    Directory of Open Access Journals (Sweden)

    PU Jijun

    2017-01-01

    Full Text Available Three different models,k-ω,DES and LES,are conducted in the analysis of the tip vortex flow field. In order to reduce the discrete error induced by the grid,mesh refinement is applied to the area of the tip vortex core in numerical simulations. The axis and tangential velocities of the tip vortex flow field with no cavitation are calculated,and the calculated velocities agree well with the experimental results. On the basis of this process,the influence of vortex roll-up on the tip vortex pressure filed is discussed,and bubble static equilibrium is proposed by which the tip vortex cavitation inception number is computed.

  17. Spread of fluid: Role of tip configurations in needles

    DEFF Research Database (Denmark)

    Gomes, Silvana; Drakidis, Alexandros Dimitrios; Silva, Patricia

    2017-01-01

    data were obtained after injecting 0.3 mL of fluid into a foamed polymer model with a velocity of 2 mm/s. The spread area and the depth were determined for 3 different types of hypodermic needles: Single channel needles with bevel tip and blunt tip and a needle with conical tip and 3 internal channels......During the injection of a fluid in a tissue model, the fluid might be affected by the needle tip configuration and the number of channels. Thus, the objective of the present work is to observe the influence of different needle tips and number of channels on the spread of a fluid. Fluid distribution...

  18. Medicinal smokes.

    Science.gov (United States)

    Mohagheghzadeh, Abdolali; Faridi, Pouya; Shams-Ardakani, Mohammadreza; Ghasemi, Younes

    2006-11-24

    All through time, humans have used smoke of medicinal plants to cure illness. To the best of our knowledge, the ethnopharmacological aspects of natural products' smoke for therapy and health care have not been studied. Mono- and multi-ingredient herbal and non-herbal remedies administered as smoke from 50 countries across the 5 continents are reviewed. Most of the 265 plant species of mono-ingredient remedies studied belong to Asteraceae (10.6%), followed by Solanaceae (10.2%), Fabaceae (9.8%) and Apiaceae (5.3%). The most frequent medical indications for medicinal smoke are pulmonary (23.5%), neurological (21.8%) and dermatological (8.1%). Other uses of smoke are not exactly medical but beneficial to health, and include smoke as a preservative or a repellent and the social use of smoke. The three main methods for administering smoke are inhalation, which accounts for 71.5% of the indications; smoke directed at a specific organ or body part, which accounts for 24.5%; ambient smoke (passive smoking), which makes up the remaining 4.0%. Whereas inhalation is typically used in the treatment of pulmonary and neurological disorders and directed smoke in localized situations, such as dermatological and genito-urinary disorders, ambient smoke is not directed at the body at all but used as an air purifier. The advantages of smoke-based remedies are rapid delivery to the brain, more efficient absorption by the body and lower costs of production. This review highlights the fact that not enough is known about medicinal smoke and that a lot of natural products have potential for use as medicine in the smoke form. Furthermore, this review argues in favor of medicinal smoke extended use in modern medicine as a form of drug delivery and as a promising source of new active natural ingredients.

  19. Modeling shoot-tip temperature in the greenhouse environment

    International Nuclear Information System (INIS)

    Faust, J.E.; Heins, R.D.

    1998-01-01

    An energy-balance model is described that predicts vinca (Catharanthus roseus L.) shoot-tip temperature using four environmental measurements: solar radiation and dry bulb, wet bulb, and glazing material temperature. The time and magnitude of the differences between shoot-tip and air temperature were determined in greenhouses maintained at air temperatures of 15, 20, 25, 30, or 35 °C. At night, shoot-tip temperature was always below air temperature. Shoot-tip temperature decreased from 0.5 to 5 °C below air temperature as greenhouse glass temperature decreased from 2 to 15 °C below air temperature. During the photoperiod under low vapor-pressure deficit (VPD) and low air temperature, shoot-tip temperature increased ≈4 °C as solar radiation increased from 0 to 600 W·m -2 . Under high VPD and high air temperature, shoot-tip temperature initially decreased 1 to 2 °C at sunrise, then increased later in the morning as solar radiation increased. The model predicted shoot-tip temperatures within ±1 °C of 81% of the observed 1-hour average shoot-tip temperatures. The model was used to simulate shoot-tip temperatures under different VPD, solar radiation, and air temperatures. Since the rate of leaf and flower development are influenced by the temperature of the meristematic tissues, a model of shoot-tip temperature will be a valuable tool to predict plant development in greenhouses and to control the greenhouse environment based on a plant temperature setpoint. (author)

  20. Integer conductance quantization of gold atomic sheets

    Science.gov (United States)

    Kurui, Yoshihiko; Oshima, Yoshifumi; Okamoto, Masakuni; Takayanagi, Kunio

    2008-04-01

    Using a transmission electron microscope combined with a scanning tunneling microscope, we find that a gold (111) or (001) atomic sheet is formed between two gold electrodes. Simultaneous conductance measurements indicate a value in the vicinity of G0 ( =2e2/h : conductance quantum), 2G0 , 3G0 , and 4G0 . Each quantum number is equal to the number of atomic strands. First-principle calculations suggest that the atomic sheet should be deformed to explain this rule. It is likely that the gold atomic sheet is stabilized by an increment of the nonlocal bond because of the deformation.

  1. Study of laser welding of copper sheets

    OpenAIRE

    A. Klimpel; A. Rzeźnikiewicz; Ł. Janik

    2007-01-01

    Purpose: Purpose of this research is to study laser autogenous welding process of short seam beads and filletwelds of lap joints of oxygen-free copper sheets 1.0 [mm] thick. On the bases of results of quality assessment itwas proved that high power diode laser (HPDL) welded lap joints of copper sheet provide mechanical propertieson the level of parent material.Design/methodology/approach: Short seam beads and fillet welds of lap joints of oxygen-free copper sheets 1,0[mm] thick were tested, t...

  2. Bifurcation of Jovian magnetotail current sheet

    Directory of Open Access Journals (Sweden)

    P. L. Israelevich

    2006-07-01

    Full Text Available Multiple crossings of the magnetotail current sheet by a single spacecraft give the possibility to distinguish between two types of electric current density distribution: single-peaked (Harris type current layer and double-peaked (bifurcated current sheet. Magnetic field measurements in the Jovian magnetic tail by Voyager-2 reveal bifurcation of the tail current sheet. The electric current density possesses a minimum at the point of the Bx-component reversal and two maxima at the distance where the magnetic field strength reaches 50% of its value in the tail lobe.

  3. Bifurcation of Jovian magnetotail current sheet

    Directory of Open Access Journals (Sweden)

    P. L. Israelevich

    2006-07-01

    Full Text Available Multiple crossings of the magnetotail current sheet by a single spacecraft give the possibility to distinguish between two types of electric current density distribution: single-peaked (Harris type current layer and double-peaked (bifurcated current sheet. Magnetic field measurements in the Jovian magnetic tail by Voyager-2 reveal bifurcation of the tail current sheet. The electric current density possesses a minimum at the point of the Bx-component reversal and two maxima at the distance where the magnetic field strength reaches 50% of its value in the tail lobe.

  4. Shapeable sheet without plastic deformation

    Science.gov (United States)

    Oppenheimer, Naomi; Witten, Thomas A.

    2015-11-01

    Randomly crumpled sheets have shape memory. In order to understand the basis of this form of memory, we simulate triangular lattices of springs whose lengths are altered to create a topography with multiple potential energy minima. We then deform these lattices into different shapes and investigate their ability to retain the imposed shape when the energy is relaxed. The lattices are able to retain a range of curvatures. Under moderate forcing from a state of local equilibrium, the lattices deform by several percent but return to their retained shape when the forces are removed. By increasing the forcing until an irreversible motion occurs, we find that the transitions between remembered shapes show cooperativity among several springs. For fixed lattice structures, the shape memory tends to decrease as the lattice is enlarged; we propose ways to counter this decrease by modifying the lattice geometry. We survey the energy landscape by displacing individual nodes. An extensive fraction of these nodes proves to be bistable; they retain their displaced position when the energy is relaxed. Bending the lattice to a stable curved state alters the pattern of bistable nodes. We discuss this shapeability in the context of other forms of material memory and contrast it with the shapeability of plastic deformation. We outline the prospects for making real materials based on these principles.

  5. Photobiology Research Laboratory (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-06-01

    This fact sheet provides information about Photobiology Research Laboratory capabilities and applications at NREL. The photobiology group's research is in four main areas: (1) Comprehensive studies of fuel-producing photosynthetic, fermentative, and chemolithotrophic model microorganisms; (2) Characterization and engineering of redox enzymes and proteins for fuel production; (3) Genetic and pathway engineering of model organisms to improve production of hydrogen and hydrocarbon fuels; and (4) Studies of nanosystems using biological and non-biological materials in hybrid generation. NREL's photobiology research capabilities include: (1) Controlled and automated photobioreactors and fermenters for growing microorganisms under a variety of environmental conditions; (2) High-and medium-throughput screening of H{sub 2}-producing organisms; (3) Homologous and heterologous expression, purification, and biochemical/biophysical characterization of redox enzymes and proteins; (4) Qualitative and quantitative analyses of gases, metabolites, carbohydrates, lipids, and proteins; (5) Genetic and pathway engineering and development of novel genetic toolboxes; and (6) Design and spectroscopic characterization of enzyme-based biofuel cells and energy conversion nanodevices.

  6. 3D Printing of Thermo-Responsive Methylcellulose Hydrogels for Cell-Sheet Engineering.

    Science.gov (United States)

    Cochis, Andrea; Bonetti, Lorenzo; Sorrentino, Rita; Contessi Negrini, Nicola; Grassi, Federico; Leigheb, Massimiliano; Rimondini, Lia; Farè, Silvia

    2018-04-10

    A possible strategy in regenerative medicine is cell-sheet engineering (CSE), i.e., developing smart cell culture surfaces from which to obtain intact cell sheets (CS). The main goal of this study was to develop 3D printing via extrusion-based bioprinting of methylcellulose (MC)-based hydrogels. Hydrogels were prepared by mixing MC powder in saline solutions (Na₂SO₄ and PBS). MC-based hydrogels were analyzed to investigate the rheological behavior and thus optimize the printing process parameters. Cells were tested in vitro on ring-shaped printed hydrogels; bulk MC hydrogels were used for comparison. In vitro tests used murine embryonic fibroblasts (NIH/3T3) and endothelial murine cells (MS1), and the resulting cell sheets were characterized analyzing cell viability and immunofluorescence. In terms of CS preparation, 3D printing proved to be an optimal approach to obtain ring-shaped CS. Cell orientation was observed for the ring-shaped CS and was confirmed by the degree of circularity of their nuclei: cell nuclei in ring-shaped CS were more elongated than those in sheets detached from bulk hydrogels. The 3D printing process appears adequate for the preparation of cell sheets of different shapes for the regeneration of complex tissues.

  7. 3D Printing of Thermo-Responsive Methylcellulose Hydrogels for Cell-Sheet Engineering

    Directory of Open Access Journals (Sweden)

    Andrea Cochis

    2018-04-01

    Full Text Available A possible strategy in regenerative medicine is cell-sheet engineering (CSE, i.e., developing smart cell culture surfaces from which to obtain intact cell sheets (CS. The main goal of this study was to develop 3D printing via extrusion-based bioprinting of methylcellulose (MC-based hydrogels. Hydrogels were prepared by mixing MC powder in saline solutions (Na2SO4 and PBS. MC-based hydrogels were analyzed to investigate the rheological behavior and thus optimize the printing process parameters. Cells were tested in vitro on ring-shaped printed hydrogels; bulk MC hydrogels were used for comparison. In vitro tests used murine embryonic fibroblasts (NIH/3T3 and endothelial murine cells (MS1, and the resulting cell sheets were characterized analyzing cell viability and immunofluorescence. In terms of CS preparation, 3D printing proved to be an optimal approach to obtain ring-shaped CS. Cell orientation was observed for the ring-shaped CS and was confirmed by the degree of circularity of their nuclei: cell nuclei in ring-shaped CS were more elongated than those in sheets detached from bulk hydrogels. The 3D printing process appears adequate for the preparation of cell sheets of different shapes for the regeneration of complex tissues.

  8. Medicinal Mushrooms

    NARCIS (Netherlands)

    Lindequist, U.; Won Kim, H.; Tiralongo, E.; Griensven, van L.J.L.D.

    2014-01-01

    Since beginning of mankind nature is the most important source of medicines. Bioactive compounds produced by living organisms can be used directly as drugs or as lead compounds for drug development. Besides, the natural material can be used as crude drug for preparation of powder or extracts. Plants

  9. Medicinal Plants.

    Science.gov (United States)

    Phillipson, J. David

    1997-01-01

    Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

  10. Predictive medicine

    NARCIS (Netherlands)

    Boenink, Marianne; ten Have, Henk

    2015-01-01

    In the last part of the twentieth century, predictive medicine has gained currency as an important ideal in biomedical research and health care. Research in the genetic and molecular basis of disease suggested that the insights gained might be used to develop tests that predict the future health

  11. Bioenergetic medicine

    Science.gov (United States)

    Swerdlow, Russell H

    2014-01-01

    Here we discuss a specific therapeutic strategy we call ‘bioenergetic medicine’. Bioenergetic medicine refers to the manipulation of bioenergetic fluxes to positively affect health. Bioenergetic medicine approaches rely heavily on the law of mass action, and impact systems that monitor and respond to the manipulated flux. Since classically defined energy metabolism pathways intersect and intertwine, targeting one flux also tends to change other fluxes, which complicates treatment design. Such indirect effects, fortunately, are to some extent predictable, and from a therapeutic perspective may also be desirable. Bioenergetic medicine-based interventions already exist for some diseases, and because bioenergetic medicine interventions are presently feasible, new approaches to treat certain conditions, including some neurodegenerative conditions and cancers, are beginning to transition from the laboratory to the clinic. Linked Articles This article is part of a themed issue on Mitochondrial Pharmacology: Energy, Injury & Beyond. To view the other articles in this issue visit http://dx.doi.org/10.1111/bph.2014.171.issue-8 PMID:24004341

  12. Personalized medicine

    DEFF Research Database (Denmark)

    Bendtzen, Klaus

    2013-01-01

    engineered anti-TNF-alpha antibody constructs now constitute one of the heaviest medicinal expenditures in many countries. All currently used TNF antagonists may dramatically lower disease activity and, in some patients, induce remission. Unfortunately, however, not all patients respond favorably, and safety...

  13. Advancing Concentrating Solar Power Research (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-02-01

    Researchers at the National Renewable Energy Laboratory (NREL) provide scientific, engineering, and analytical expertise to help advance innovation in concentrating solar power (CSP). This fact sheet summarizes how NREL is advancing CSP research.

  14. Western Abandoned Uranium Mine Region Fact Sheets

    Science.gov (United States)

    Fact sheets related to Western Abandoned Uranium Mine (AUM) Region, more than 100 abandoned uranium mine claims located along the Little Colorado River and Highway 89, ain the Cameron, Coalmine Canyon, Bodaway/Gap, and Leupp Chapters in Northern Arizona.

  15. Drinking Water Fact Sheet: Coliform Bacteria

    OpenAIRE

    Mesner, Nancy; Daniels, Barbara

    2010-01-01

    This fact sheet provides information about coliform bacteria. Including sections about what coliform bacteria is, how it enters drinking water, health concerns from exposure, drinking water standards, and how to treat drinking water that contains coliforms.

  16. Hydrologic Outlets of the Greenland Ice Sheet

    Data.gov (United States)

    National Aeronautics and Space Administration — The Hydrologic Outlets of the Greenland Ice Sheet data set contains GIS point shapefiles that include 891 observed and potential hydrologic outlets of the Greenland...

  17. HIV/AIDS Clinical Trials Fact Sheet

    Science.gov (United States)

    ... AIDS Drugs Clinical Trials Apps skip to content HIV Overview Home Understanding HIV/AIDS Fact Sheets HIV/ ... 4 p.m. ET) Send us an email HIV/AIDS Clinical Trials Last Reviewed: August 25, 2017 ...

  18. Proctor Creek Boone Boulevard Fact Sheet

    Science.gov (United States)

    This fact sheet provides an overview of the Proctor Creek watershed and community, green infrastructure, the Boone Boulevard Green Street Project Conceptual Design, and the added value and application of Health Impact Assessment (HIA) to the project.

  19. Clean Cities Program Contacts (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-03-01

    This fact sheet provides contact information for program staff of the U.S. Department of Energy's Clean Cities program, as well as contact information for the nearly 100 local Clean Cities coalitions across the country.

  20. fibrin–chitosan–sodium alginate composite sheet

    Indian Academy of Sciences (India)

    sodium alginate composite (F–C–SA) in sheet form. F–C–SA composite was prepared and characterized for its physicochemical properties like water absorption capacity, surface morphology, FTIR spectra and mechanical properties.

  1. Matrix Models and String World Sheet Duality

    OpenAIRE

    de Alwis, S. P.

    1997-01-01

    The scaling limit used recently to derive matrix models, and a certain analyticity assumption, are invoked to argue that the agreement between some matrix model calculations and supergravity is a consequence of string world sheet duality.

  2. Nanotechnology for Site Remediation: Fact Sheet

    Science.gov (United States)

    This fact sheet presents a snapshot of nanotechnology and its current uses in remediation. It presents information to help site project managers understand the potential applications of this group of technologies at their sites.

  3. Greenland Radar Ice Sheet Thickness Measurements

    Data.gov (United States)

    National Aeronautics and Space Administration — Two 150-MHz coherent radar depth sounders were developed and flown over the Greenland ice sheet to obtain ice thickness measurements in support of PARCA...

  4. Coordinated Specialty Care Fact Sheet and Checklist

    Science.gov (United States)

    ... Checklist Share Coordinated Specialty Care Fact Sheet and Checklist Download PDF Download ePub Order a free hardcopy ... webpage: http://www.nimh.nih.gov/raise . CSC Checklist If you are interested in a CSC program, ...

  5. Polycystic Ovary Syndrome (PCOS) Fact Sheet

    Science.gov (United States)

    ... this section Home A-Z Health Topics Polycystic ovary syndrome Polycystic ovary syndrome > A-Z Health Topics Polycystic ovary syndrome fact sheet (PDF, 126 KB) Normal ovary and polycystic ovary The javascript used in this widget is ...

  6. Geometry of Thin Nematic Elastomer Sheets

    Science.gov (United States)

    Aharoni, Hillel; Sharon, Eran; Kupferman, Raz

    2014-12-01

    A thin sheet of nematic elastomer attains 3D configurations depending on the nematic director field upon heating. In this Letter, we describe the intrinsic geometry of such a sheet and derive an expression for the metric induced by general nematic director fields. Furthermore, we investigate the reverse problem of constructing a director field that induces a specified 2D geometry. We provide an explicit recipe for how to construct any surface of revolution using this method. Finally, we show that by inscribing a director field gradient across the sheet's thickness, one can obtain a nontrivial hyperbolic reference curvature tensor, which together with the prescription of a reference metric allows dictation of actual configurations for a thin sheet of nematic elastomer.

  7. Wall Insulation; BTS Technology Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    Southface Energy Institute; Tromly, K.

    2000-11-07

    Properly sealed, moisture-protected, and insulated walls help increase comfort, reduce noise, and save on energy costs. This fact sheet addresses these topics plus advanced framing techniques, insulation types, wall sheathings, and steps for effective wall construction and insulation.

  8. Fact Sheet: Early Warning Signs of Psychosis

    Science.gov (United States)

    ... items) Share Fact Sheet: Early Warning Signs of Psychosis Download PDF Download ePub Order a free hardcopy ... show changes in his or her behaviors before psychosis develops. The list below includes several warning signs ...

  9. Tipping toward sustainability: emerging pathways of transformation.

    Science.gov (United States)

    Westley, Frances; Olsson, Per; Folke, Carl; Homer-Dixon, Thomas; Vredenburg, Harrie; Loorbach, Derk; Thompson, John; Nilsson, Måns; Lambin, Eric; Sendzimir, Jan; Banerjee, Banny; Galaz, Victor; van der Leeuw, Sander

    2011-11-01

    This article explores the links between agency, institutions, and innovation in navigating shifts and large-scale transformations toward global sustainability. Our central question is whether social and technical innovations can reverse the trends that are challenging critical thresholds and creating tipping points in the earth system, and if not, what conditions are necessary to escape the current lock-in. Large-scale transformations in information technology, nano- and biotechnology, and new energy systems have the potential to significantly improve our lives; but if, in framing them, our globalized society fails to consider the capacity of the biosphere, there is a risk that unsustainable development pathways may be reinforced. Current institutional arrangements, including the lack of incentives for the private sector to innovate for sustainability, and the lags inherent in the path dependent nature of innovation, contribute to lock-in, as does our incapacity to easily grasp the interactions implicit in complex problems, referred to here as the ingenuity gap. Nonetheless, promising social and technical innovations with potential to change unsustainable trajectories need to be nurtured and connected to broad institutional resources and responses. In parallel, institutional entrepreneurs can work to reduce the resilience of dominant institutional systems and position viable shadow alternatives and niche regimes.

  10. Transjugular Intrahepatic Portosystemic Shunt (TIPS): Current Status and Future Possibilities

    International Nuclear Information System (INIS)

    Bilbao, Jose Ignacio; Quiroga, Jorge; Herrero, Jose Ignacio; Benito, Alberto

    2002-01-01

    Since the insertion of the first TIPS in 1989 much has been learned about this therapeutic procedure. It has an established role for the treatment of some complications of portal hypertension: prevention of recurrent variceal bleeding and rescue of patients with acute uncontrollable variceal bleeding. In addition TIPS is useful for Budd-Chiari syndrome, refractory ascites and hepatorenal syndrome, although its specific role in these indications remains to be definitively established. However, the decrease in sinusoidal blood flow induced by TIPS can lead to the patient developing hepatic encephalopathy and liver failure in some cases. Therefore, TIPS should be used with caution in patients with very poor liver function. From a technical point of view, successful placement of TIPS is achieved in more than 98% of cases by experienced groups. At present, evaluation of TIPS dysfunction based on morphology probably leads to an overdiagnosis of this complication since most of these cases are not associated with clinical manifestations (recurrent bleeding or refractory ascites). The major disadvantage of TIPS remains its poor long-term patency requiring a mandatory surveillance program. The indicator for shunt function/malfunction should be the portosystemic pressure gradient, which is best assessed by intravascular measurements. Shunt obstructions may be prevented or reduced by the use of stent-grafts in the future

  11. Investigation on tip enhanced Raman spectra of graphene

    Science.gov (United States)

    Li, Xinjuan; Liu, Yanqi; Zeng, Zhuo; Wang, Peijie; Fang, Yan; Zhang, Lisheng

    2018-02-01

    Tip-enhanced Raman scattering (TERS) is a promising analytical approach for some two-dimensional materials and offers the possibility to correlate imaging and chemical data. Tip-enhanced Raman spectra of graphene are discussed in some details, including substrate, gap between tip-apex and sample surface as well as Ag-nanowire. The TERS spectra give special emphasis to the possibility of TERS tip to induce a large number of defects only while got the tip attached to sample surface. Then the dependence of the TERS spectra of graphene and gap between the probe tip and sample surface was studied, and distribution features of electromagnetic (EM) field around tip were also simulated by finite-difference time-domain (FDTD). The Raman signal enhancement of graphene was further discussed with respect to experimental data. Furthermore, the Ag-nanowire as a nano-antenna could significantly enhance the weak Raman signal of D-band of monolayer graphene is shown, and the TERS spectra of graphene with regard to different regions of Ag-nanowires (endpoints, body) were obtained toward investigating into the distribution of electromagnetic field.

  12. A Blade Tip Timing Method Based on a Microwave Sensor

    Directory of Open Access Journals (Sweden)

    Jilong Zhang

    2017-05-01

    Full Text Available Blade tip timing is an effective method for blade vibration measurements in turbomachinery. This method is increasing in popularity because it is non-intrusive and has several advantages over the conventional strain gauge method. Different kinds of sensors have been developed for blade tip timing, including optical, eddy current and capacitance sensors. However, these sensors are unsuitable in environments with contaminants or high temperatures. Microwave sensors offer a promising potential solution to overcome these limitations. In this article, a microwave sensor-based blade tip timing measurement system is proposed. A patch antenna probe is used to transmit and receive the microwave signals. The signal model and process method is analyzed. Zero intermediate frequency structure is employed to maintain timing accuracy and dynamic performance, and the received signal can also be used to measure tip clearance. The timing method uses the rising and falling edges of the signal and an auto-gain control circuit to reduce the effect of tip clearance change. To validate the accuracy of the system, it is compared experimentally with a fiber optic tip timing system. The results show that the microwave tip timing system achieves good accuracy.

  13. Force focusing in confined fibres and sheets

    Energy Technology Data Exchange (ETDEWEB)

    Romero, Victor; Cerda, Enrique [Departamento de Fisica, Universidad de Santiago, Av. Ecuador 3493, Santiago (Chile); Witten, T A; Liang Tao [James Franck Institute, University of Chicago, Chicago IL 60637 (United States)], E-mail: t-witten@uchicago.edu

    2008-07-07

    A thin fibre or sheet curled into a circular container has a detached region whose shape and force ratios are independent of material properties and container radius. We compute this shape and compare it with experiments. The discrete forces acting at either end of the detached region have a ratio that depends only on the length of the fibre or sheet relative to the circle radius. We calculate this force ratio in three regimes of circle radius. (fast track communication)

  14. Preparation and transplantation of photoreceptor sheets.

    Science.gov (United States)

    Huang, J C; Ishida, M; Hersh, P; Sugino, I K; Zarbin, M A

    1998-06-01

    Photoreceptor (PR) transplantation may be a treatment for blindness secondary to PR degeneration. We studied different technical aspects of PR-sheet preparation. Geographic variation in the thickness of the cat PR layer (from the outer segments to the outer plexiform layer) and inner retina (width of the remainder of the retina) was studied. PR sheets (cat and human) were prepared through gelatin embedding and subsequent vibratoming or excimer laser ablation. Cat PR sheets were evaluated after transplantation. The thickness of the cat PR layer and inner retina varied in different regions. The superior central retina, including the area centralis, was thickest (PR layer: 115-123 microm, entire retina: 225-230 microm, in fixed tissue). The peripheral retina was approximately 40% thinner than the center. Fresh retina was approximately 7.9% thicker than the fixed retina. Both vibratomy and excimer laser ablation removed the inner retina, leaving a PR-layer sheet with good morphology. To produce good quality PR sheets with vibratomy, use of different gelatin concentrations (2% to 35%) at various stages of sheet preparation was crucial. To produce PR sheets of uniform thickness with excimer laser ablation, control of fluid on the retinal surface was critical. Twenty-four hours after PR transplantation surgery, donor PR cells were well oriented and in close contact with host retinal pigment epithelial cells. Gelatin supporting the transplant dissolved as early as 100 min after surgery. We confirmed and expanded the work of previous investigators and showed that cat and human PR sheets can be manufactured using vibratomy or excimer laser ablation. This preparation provides a well oriented and organized PR cell layer after transplantation.

  15. Bent versus straight tips in micropulsed longitudinal phacoemulsification.

    Science.gov (United States)

    Stagg, Brian C; Gupta, Isha; Cahoon, Judd; Ronquillo, Cecinio; Shi, Dallas; Zaugg, Brian; Gardiner, Gareth; Barlow, William R; Pettey, Jeff H; Aabid Farukhi, M; Jensen, Jason; Olson, Randall J

    2015-10-01

    The aim of this study was to evaluate bent and straight phacoemulsification tips to determine which tip is more efficient in removal of lens fragments, using micropulsed longitudinal ultrasound in phacoemulsification. In vitro laboratory study. The John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, was the study setting. Pig lenses hardened in a manner comparable with dense human cataracts were cut into 2-mm cubes and removed with micropulsed longitudinal ultrasound using settings previously shown to be optimally efficient (6 milliseconds on and 6 milliseconds off for a bent tip). To verify this time as most efficient for a straight tip, we also tested times of 5, 6, and 7 milliseconds time on and off. The tips were either straight or with a 20-degree bend. Twenty cubes were used for each comparative run. For the straight tip, 6 milliseconds on (1.56 ± 0.815 seconds) was significantly more efficient than 7 milliseconds on (2.45 ± 1.56 seconds, p = 0.001) and not significantly more efficient than 5 milliseconds on (1.69 ± 0.86 seconds, p = 0.43). Five milliseconds off time (1.45 ± 0.76s) was more efficient than 6 milliseconds (2.06 ± 1.37 seconds, p = 0.004) and 7 milliseconds off (2.18 ± 1.24s, p = 0.001). The straight tip was more efficient than the bent tip (1.38 ± 0.83 versus 2.93 ± 2.14 seconds, p = 0.006). Results are contrary to accepted common belief. Micropulsed longitudinal phacoemulsification is more efficient with a straight rather than a bent tip. Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  16. Alar setback technique: a controlled method of nasal tip deprojection.

    Science.gov (United States)

    Foda, H M

    2001-11-01

    To describe an alar cartilage-modifying technique aimed at decreasing nasal tip projection in cases with overdeveloped alar cartilages and to compare it with other deprojection techniques used to correct such deformity. Selected case series. University and private practice settings in Alexandria, Egypt. Twenty patients presenting for rhinoplasty who had overprojected nasal tips primarily due to overdeveloped alar cartilages. All cases were primary cases except for one patient, who had undergone 2 previous rhinoplasties. An external rhinoplasty approach was used to set back the alar cartilages by shortening their medial and lateral crura. The choice of performing a high or low setback depended on the preexisting lobule-to-columella ratio. Following the setback, the alar cartilages were reconstructed in a fashion that increased the strength and stability of the tip complex. Subjective evaluation included clinical examination, analysis of preoperative and postoperative photographs, and patient satisfaction. Objective evaluation of nasal tip projection, using the Goode ratio and the nasofacial angle, was performed preoperatively and repeated at least 6 months postoperatively. A low setback was performed in 16 cases (80%) and a high setback in 4 (20%). The mean follow-up period was 18 months (range, 6-36 months). The technique effectively deprojected the nasal tip as evidenced by the considerable postoperative decrease in values of the Goode ratio and the nasofacial angle. No complications were encountered and no revision surgical procedures were required. The alar setback technique has many advantages; it results in precise predictable amounts of deprojection, controls the degree of tip rotation, preserves the natural contour of the nasal tip, respects the tip support mechanisms, increases the strength and stability of nasal tip complex, preserves or restores the normal lobule-to-columella proportion, and does not lead to alar flaring. However, the technique requires

  17. Balance of the West Antarctic Ice Sheet

    Science.gov (United States)

    2002-01-01

    For several decades, measurements of the West Antarctic Ice Sheet showed it to be retreating rapidly. But new data derived from satellite-borne radar sensors show the ice sheet to be growing. Changing Antarctic ice sheets remains an area of high scientific interest, particularly in light of recent global warming concerns. These new findings are significant because scientists estimate that sea level would rise 5-6 meters (16-20 feet) if the ice sheet collapsed into the sea. Do these new measurements signal the end of the ice sheet's 10,000-year retreat? Or, are these new satellite data simply much more accurate than the sparse ice core and surface measurements that produced the previous estimates? Another possibility is that the ice accumulation may simply indicate that the ice sheet naturally expands and retreats in regular cycles. Cryologists will grapple with these questions, and many others, as they examine the new data. The image above depicts the region of West Antarctica where scientists measured ice speed. The fast-moving central ice streams are shown in red. Slower tributaries feeding the ice streams are shown in blue. Green areas depict slow-moving, stable areas. Thick black lines depict the areas that collect snowfall to feed their respective ice streams. Reference: Ian Joughin and Slawek Tulaczyk Science Jan 18 2002: 476-480. Image courtesy RADARSAT Antarctic Mapping Project

  18. Antibubbles and fine cylindrical sheets of air

    KAUST Repository

    Beilharz, D.

    2015-08-14

    Drops impacting at low velocities onto a pool surface can stretch out thin hemispherical sheets of air between the drop and the pool. These air sheets can remain intact until they reach submicron thicknesses, at which point they rupture to form a myriad of microbubbles. By impacting a higher-viscosity drop onto a lower-viscosity pool, we have explored new geometries of such air films. In this way we are able to maintain stable air layers which can wrap around the entire drop to form repeatable antibubbles, i.e. spherical air layers bounded by inner and outer liquid masses. Furthermore, for the most viscous drops they enter the pool trailing a viscous thread reaching all the way to the pinch-off nozzle. The air sheet can also wrap around this thread and remain stable over an extended period of time to form a cylindrical air sheet. We study the parameter regime where these structures appear and their subsequent breakup. The stability of these thin cylindrical air sheets is inconsistent with inviscid stability theory, suggesting stabilization by lubrication forces within the submicron air layer. We use interferometry to measure the air-layer thickness versus depth along the cylindrical air sheet and around the drop. The air film is thickest above the equator of the drop, but thinner below the drop and up along the air cylinder. Based on microbubble volumes, the thickness of the cylindrical air layer becomes less than 100 nm before it ruptures.

  19. Buckling Behavior of Substrate Supported Graphene Sheets

    Directory of Open Access Journals (Sweden)

    Kuijian Yang

    2016-01-01

    Full Text Available The buckling of graphene sheets on substrates can significantly degrade their performance in materials and devices. Therefore, a systematic investigation on the buckling behavior of monolayer graphene sheet/substrate systems is carried out in this paper by both molecular mechanics simulations and theoretical analysis. From 70 simulation cases of simple-supported graphene sheets with different sizes under uniaxial compression, two different buckling modes are investigated and revealed to be dominated by the graphene size. Especially, for graphene sheets with length larger than 3 nm and width larger than 1.1 nm, the buckling mode depends only on the length/width ratio. Besides, it is revealed that the existence of graphene substrate can increase the critical buckling stress and strain to 4.39 N/m and 1.58%, respectively, which are about 10 times those for free-standing graphene sheets. Moreover, for graphene sheets with common size (longer than 20 nm, both theoretical and simulation results show that the critical buckling stress and strain are dominated only by the adhesive interactions with substrate and independent of the graphene size. Results in this work provide valuable insight and guidelines for the design and application of graphene-derived materials and nano-electromechanical systems.

  20. Buckling Behavior of Substrate Supported Graphene Sheets.

    Science.gov (United States)

    Yang, Kuijian; Chen, Yuli; Pan, Fei; Wang, Shengtao; Ma, Yong; Liu, Qijun

    2016-01-07

    The buckling of graphene sheets on substrates can significantly degrade their performance in materials and devices. Therefore, a systematic investigation on the buckling behavior of monolayer graphene sheet/substrate systems is carried out in this paper by both molecular mechanics simulations and theoretical analysis. From 70 simulation cases of simple-supported graphene sheets with different sizes under uniaxial compression, two different buckling modes are investigated and revealed to be dominated by the graphene size. Especially, for graphene sheets with length larger than 3 nm and width larger than 1.1 nm, the buckling mode depends only on the length/width ratio. Besides, it is revealed that the existence of graphene substrate can increase the critical buckling stress and strain to 4.39 N/m and 1.58%, respectively, which are about 10 times those for free-standing graphene sheets. Moreover, for graphene sheets with common size (longer than 20 nm), both theoretical and simulation results show that the critical buckling stress and strain are dominated only by the adhesive interactions with substrate and independent of the graphene size. Results in this work provide valuable insight and guidelines for the design and application of graphene-derived materials and nano-electromechanical systems.

  1. Twelve tips on teaching and learning humanism in medical education.

    Science.gov (United States)

    Cohen, Libby Gordon; Sherif, Youmna Ashraf

    2014-08-01

    The teaching of humanistic values is recognized as an essential component of medical education and continuing professional development of physicians. The application of humanistic values in medical care can benefit medical students, clinicians and patients. This article presents 12 tips on fostering humanistic values in medical education. The authors reviewed the literature and present 12 practical tips that are relevant to contemporary practices. The tips can be used in teaching and sustaining humanistic values in medical education. Humanistic values can be incorporated in formal preclinical environments, the transition into clinical settings, medical curricula and clinical clerkships. Additionally, steps can be taken so that medical educators and institutions promote and sustain humanistic values.

  2. Positive lidocaine toxicology screen after J-Tip for venipuncture.

    Science.gov (United States)

    Bhupali, Chetan; Cummings, Brian M; Parker, Lois; Young, Robert; Noviski, Natan

    2013-12-01

    Venipuncture is common in children, and topical anesthetics are often used to alleviate the pain of the procedure. The J-Tip (National Medical Products, Inc, Irvine, Calif) device has become popular as a rapid and effective means of delivering lidocaine noninvasively. We report a case of a positive lidocaine blood toxicology screen after the use of the J-Tip device in a child pre-venipuncture. A repeat toxicology screen obtained 1 hour later by venipuncture without J-Tip use was negative. This report serves to remind clinicians that topical anesthetics may interfere with toxicology assays, leading to unreliable toxicology results.

  3. On the opening of premixed Bunsen flame tips

    Science.gov (United States)

    Law, C. K.; Ishizuka, S.; Cho, P.

    1982-01-01

    The local extinction of Bunsen flame tip and edges of hydrocarbon/air premixtures has been experimentally investigated using a variety of burners. Results show that, while for both rich propane/air and butane/air mixtures tip opening occurs at a constant fuel equivalence ratio of 1.44 and is therefore independent of the intensity, uniformity, and configuration of the approach flow, for rich methane/air flames burning is intensified at the tip and therefore opening is not possible. These results substantiate the concept and dominance of the diffusional stratification mechanism in causing extinction, and clarify the theoretical predictions on the possible opening of two-dimensional flame wedges.

  4. History of the Greenland Ice Sheet: paleoclimatic insights

    DEFF Research Database (Denmark)

    Alley, Richard B.; Andrews, John Thomas; Brigham-Grette, Julia

    2010-01-01

    -sheet changes. In contrast, there are no documented major ice-sheet changes that occurred independent of temperature changes. Moreover, snowfall has increased when the climate warmed, but the ice sheet lost mass nonetheless; increased accumulation in the ice sheet's center has not been sufficient to counteract...

  5. 37 CFR 3.31 - Cover sheet content.

    Science.gov (United States)

    2010-07-01

    ... the cover sheet must either: (i) Place a symbol comprised of letters, numbers, and/or punctuation... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Cover sheet content. 3.31... COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Cover Sheet Requirements § 3.31 Cover sheet...

  6. 17 CFR 210.6-04 - Balance sheets.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Balance sheets. 210.6-04... sheets. This rule is applicable to balance sheets filed by registered investment companies except for... of this part. Balance sheets filed under this rule shall comply with the following provisions: Assets...

  7. Environmental medicine

    International Nuclear Information System (INIS)

    Steneberg, A.

    1996-01-01

    'Environmental medicine' deals with the manifold health problems from environmental factors of chemical, physical and psychosocial origin that are possible or have been observed. The book gives insight into the current state of knowledge of environmental medicine institutions, possibilities of diagnosis and therapeutic methods. It offers a systematic overview of pollutant sources and pollutant effects and points out, inter alia, syndromes that are discussed in connection with environmental factors: not only allergies and carcinogenous diseases but also symptom complexes that are hard to diagnose by ordinary methods such as the sick-building syndrome, multiple sensitivity to chemicals, electrosensitivity, amalgam intoxications, disorders due to wood preservatives and fungal diseases. The lingering course of a disease and a set of symptoms varying from one patient to another are the rule, not the exception, because environmental diseases are due above all to the chronic uptake of low pollutant doses (orig./MG) [de

  8. Comparison of different types of phacoemulsification tips. I. Quantitative analysis of elemental composition and tip surface microroughness.

    Science.gov (United States)

    Tsaousis, Konstantinos T; Werner, Liliana; Perez, Jesus Paulo; Li, He J; Reiter, Nicholas; Guan, Jia J; Mamalis, Nick

    2016-09-01

    To evaluate the elemental composition of phacoemulsification tips and their surface roughness in the microscale. John A. Moran Eye Center and Utah Nanofab, College of Engineering, University of Utah, Salt Lake City, Utah, USA. Experimental study. Seven types of phacoemulsification tips were studied. The phaco tips were examined through energy-dispersive x-ray spectroscopy (EDS) and x-ray photoelectron spectroscopy (XPS) for elemental composition. In addition, the roughness of the opening in all tips was assessed through 3-dimensional white-light interferometry. Elemental analysis showed considerable differences in the surface layers between manufacturers. Alcon tips had a thinner oxidized titanium (Ti) layer in their surface. Through XPS, vanadium was not detected in the superficial layers of any tip, but only in deeper levels. The microroughness surface analysis showed comparable results regarding their root-mean-square (RMS) metric. Maximum peak valley distance values varied and appeared to be dependent on the quality of material process rather than the material itself. Phacoemulsification tips are made of Ti alloys and showed differences between models, especially regarding their composition in the superficial layers. Their opening end roughness showed an overall appropriate RMS value of less than 1.0 μm in all cases. The existence of small defected areas highlights the importance of adequate quality control of these critical surgical instruments. None of the authors has a financial or proprietary interest in any material or method mentioned. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  9. Transfusion Medicine

    Directory of Open Access Journals (Sweden)

    Smit Sibinga CT

    2013-07-01

    Full Text Available Cees Th. Smit Sibinga ID Consulting, Zuidhorn, The NetherlandsTransfusion Medicine is a bridging science, spanning the evidence-based practice at the bedside with the social sciences in the community.     Transfusion Medicine starts at the bedside. Surprisingly, only recently that has become rediscovered with the development of ‘patient blood management’ and ‘patient centered’ approaches to allow the growth of an optimal and rational patient care through supportive hemotherapy – safe and effective, affordable and accessible.1    Where transfusion of blood found its origin in the need of a patient, it has drifted away for a long period of time from the bedside and has been dominated for almost a century by laboratory sciences. At least the first ten editions of the famous and well reputed textbook Mollison’s Blood Transfusion in Clinical Medicine contained only a fraction on the actual bedside practice of transfusion medicine and did not focus at all on patient blood management.2    This journal will focus on all aspects of the transfusion chain that immediately relate to the bedside practice and clinical use of blood and its components, and plasma derivatives as integral elements of a human transplant tissue. That includes legal and regulatory aspects, medical, ethical and cultural aspects, pure science and pathophysiology of disease and the impact of transfusion of blood, as well as aspects of the epidemiology of blood transfusion and clinical indications, and cost-effectiveness. Education through timely and continued transfer of up to date knowledge and the application of knowledge in clinical practice to develop and maintain clinical skills and competence, with the extension of current educational approaches through e-learning and accessible ‘apps’ will be given a prominent place.

  10. ENERGY MEDICINE

    OpenAIRE

    Srinivasan, T. M.

    1987-01-01

    Energy medicine is the most comprehensive concept introduced in medical diagnostics and therapy to account for a whole range of phenomena and methods available to help an individual proceed from sickness to health. The modern medical theories do not account for, much less accept many traditional therapies due to deep suspicion that the older methods are not scientific. However, the Holistic Health groups around the world have now created an environment for therapies which work at subtle energ...

  11. Transfusion medicine

    International Nuclear Information System (INIS)

    Murawski, K.; Peetoom, F.

    1986-01-01

    These proceedings contain 24 selections, including papers presented at the conference of American Red Cross held in May 1985, on the Subject of transfusion medicine. Some of the titles are: Fluosol/sup R/-DA in Radiation Therapy; Expression of Cloned Human Factor VIII and the Molecular Basis of Gene Defects that Cause Hemophilia; DNA-Probing Assay in the Detection of Hepatitis B Virus Genome in Human Peripheral Blood Cells; and Monoclonal Antibodies: Convergence of Technology and Application

  12. Tipping points in Anthropocene fluvial dynamics

    Science.gov (United States)

    Notebaert, Bastiaan; Broothaerts, Nils; Verstraeten, Gert; Berger, Jean-François; Houbrechts, Geoffrey

    2016-04-01

    the river partially maintains its braided pattern. The Amblève River in the Belgian Ardennes uplands underwent less dramatic changes. Large parts of the catchment are deforested during the last 700 years, leading to an increase in floodplain sedimentation. Despite this major sediment pulse, change in floodplain morphology remained limited to an increase in bank height. We argue that a combination of floodplain and channel morphology, the fine texture of supplied sediment and the high stream power of channel forming events result is a system that is less sensitive to change. Also the relative short time of impact may play a role. These three examples demonstrate the varying impact of human deforestation on floodplain geomorphology. For the Dijle and Valdaine region this lead to dramatic changes once a certain tipping point is reached. In contrast the Amblève river is more resilient to human impact due to its specific morphological setting. The morphology of the catchments and the nature of supplied sediments plays a major role in the sensitivity of fluvial systems to environmental impact. Once the tipping points are reached, it is difficult for the river to revert to its original state and floodplains remain highly impacted.

  13. Tax Tips for Forest Landowners for the 2013 Tax Year

    Science.gov (United States)

    Linda Wang; John Greene

    2013-01-01

    This annual bulletin provides federal income tax reporting tips to assist forest landowners and their advisers in filing their 2013 income tax returns. The information presented here is current as of Sept. 15, 2013.

  14. DEFORMATION INFLUENCE ON A LIFETIME OF WELDING ELECTRODE TIPS

    Directory of Open Access Journals (Sweden)

    Ján Viňáš

    2009-02-01

    Full Text Available The contribution deals with the influence of welding electrode tips deformation on their lifetime. The influence of material properties, production technology and the intensity of welding electrodes load on their lifetime are presented. The electrode tips of the most used type of CuCr1Zr alloy of three basic standard shapes before and after the process of welding are evaluated. The process of welding is realized with low, middle and maximum welding parameters on programmable pneumatic spot welding machine VTS BPK 20. The influence of welding parameters on chosen material characteristics of welding tips is observed. Through the use of upsetting test, dependency of forming strength and deformation of material on used technology of welding tip production is observed.

  15. Treating Cataracts: Dr. Rachel Bishop's Top Tips for Your Eyes

    Science.gov (United States)

    ... please turn JavaScript on. Feature: Treating Cataracts Dr. Rachel Bishop's Top Tips for Your Eyes Past Issues / ... exams, a healthy lifestyle, and eye protection. Dr. Rachel Bishop, chief of consult services at the National ...

  16. CPAP Machines: Tips for Avoiding 10 Common Problems

    Science.gov (United States)

    CPAP machines: Tips for avoiding 10 common problems CPAP is an important treatment for obstructive sleep apnea, but may ... common treatment for obstructive sleep apnea. A CPAP machine uses a hose and mask or nosepiece to ...

  17. TIPS to reduce Pressure Decreasess rebleed and Death (Monescillo ...

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. TIPS to reduce Pressure Decreasess rebleed and Death (Monescillo A, Oct 2004, Hepatology). 116 Bleeders. Liver Pressure > 20 mm Hg - 52 Patients (high risk)

  18. Sharp tipped plastic hollow microneedle array by microinjection moulding

    Science.gov (United States)

    Yung, K. L.; Xu, Yan; Kang, Chunlei; Liu, H.; Tam, K. F.; Ko, S. M.; Kwan, F. Y.; Lee, Thomas M. H.

    2012-01-01

    A method of producing sharp tipped plastic hollow microneedle arrays using microinjection moulding is presented in this paper. Unlike traditional approaches, three mould inserts were used to create the sharp tips of the microneedles. Mould inserts with low surface roughness were fabricated using a picosecond laser machine. Sharp tipped plastic hollow microneedles 500 µm in height were fabricated using a microinjection moulding machine developed by the authors’ group. In addition, the strength of the microneedle was studied by simulation and penetration experiments. Results show that the microneedles can penetrate into skin, delivering liquid successfully without any breakage or severe deformation. Techniques presented in this paper can be used to fabricate sharp tipped plastic hollow microneedle arrays massively with low cost.

  19. Sharp tipped plastic hollow microneedle array by microinjection moulding

    International Nuclear Information System (INIS)

    Yung, K L; Xu, Yan; Kang, Chunlei; Liu, H; Tam, K F; Ko, S M; Kwan, F Y; Lee, Thomas M H

    2012-01-01

    A method of producing sharp tipped plastic hollow microneedle arrays using microinjection moulding is presented in this paper. Unlike traditional approaches, three mould inserts were used to create the sharp tips of the microneedles. Mould inserts with low surface roughness were fabricated using a picosecond laser machine. Sharp tipped plastic hollow microneedles 500 µm in height were fabricated using a microinjection moulding machine developed by the authors’ group. In addition, the strength of the microneedle was studied by simulation and penetration experiments. Results show that the microneedles can penetrate into skin, delivering liquid successfully without any breakage or severe deformation. Techniques presented in this paper can be used to fabricate sharp tipped plastic hollow microneedle arrays massively with low cost. (paper)

  20. Tips to Help Parents Manage Their Child's Asthma Every Day

    Science.gov (United States)

    ... Breathing Easier Tips to Help Parents Manage Their Child's Asthma Every Day Past Issues / Fall 2013 Table of ... doctor, to write down how to manage your child's asthma, routinely on a daily basis and during an ...

  1. Energy Efficiency and Renewable Energy in SIPs and TIPs

    Science.gov (United States)

    Tools and guides to encourage state, tribal and local agencies to consider incorporating Energy Efficiency (EE) and Renewable Energy (RE) policies and programs in their State and Tribal Implementation Plans (SIPs/TIPs).

  2. Rapid tryptic mapping using enzymatically active mass spectrometer probe tips

    Energy Technology Data Exchange (ETDEWEB)

    Dogruel, D.; Williams, P.; Nelson, R.W. [Arizona State Univ., Tempe, AZ (United States)

    1995-12-01

    A method has been developed for rapid, sensitive, and accurate tryptic mapping of polypeptides using matrix-assisted laser desorption/ionization time-of-flight mass analysis. The technique utilizes mass spectrometer probe tips which have been activated through the covalent immobilization of trypsin. The enzymatically active probe tips were used for the tryptic mapping of chicken egg lysozyme and the results compared with those obtained using either free trypsin or agarose-immobilized trypsin. A significant increase in the overall sensitivity of the process was observed using the active probe tips, as well as the production of more characteristic proteolytic fragments and the elimination of background signals due to the autolysis of the trypsin. Further, probe tip digestions were found to be rapid and convenient. 19 refs., 6 figs., 2 tabs.

  3. Children with Chronic Kidney Disease: Tips for Parents

    Science.gov (United States)

    ... Donate A to Z Health Guide Children With Chronic Kidney Disease: Tips for Parents Print Email If your child has been diagnosed with chronic kidney disease, you are no doubt feeling distressed and bewildered. ...

  4. Back-to-School Health Tips: Exercise and Sleep

    Science.gov (United States)

    ... Feature: Back-to-School Health Tips: Exercise and Sleep Past Issues / Fall 2014 Table of Contents 6 " ... healthy weight Build sturdy muscles, bones, and joints Sleep better at night More time in front of ...

  5. 5 Tips for Using Your Microwave Oven Safely

    Science.gov (United States)

    ... Consumers Consumer Updates 5 Tips for Using Your Microwave Oven Safely Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Safe Microwave Oven Use When you operate a microwave oven, ...

  6. Rheumatoid Arthritis Pain: Tips for Protecting Your Joints

    Science.gov (United States)

    Rheumatoid arthritis pain: Tips for protecting your joints Use these joint protection techniques to help you stay in control of your rheumatoid arthritis pain. By Mayo Clinic Staff Joint protection is ...

  7. Sediment transport near the Peninsular tip of India

    Digital Repository Service at National Institute of Oceanography (India)

    Jena, B.K.; Chandramohan, P.

    Studies were undertaken at Kolachel on the western side of the Peninsular tip from April 1995 to April 1996, for a period of one year. Monthly measurements were made on littoral environment observations (LEO) and beach level variations. Longshore...

  8. Be More Involved in Your Health Care: Tips for Patients

    Science.gov (United States)

    ... Rockville, MD. http://www.ahrq.gov/patients-consumers/patient-involvement/ask-your-doctor/tips-and-tools/beinvolved.html Back to top Accessibility Disclaimers EEO Electronic Policies FOIA HHS Digital Strategy HHS Nondiscrimination Notice ...

  9. Tips for Coping: The Music Educator and Stress.

    Science.gov (United States)

    Radocy, Rudolf E.; Heller, George N.

    1982-01-01

    Discusses sources of stress for music teachers and offers tips for coping with it. Relaxation exercises, physical exercise, and a change of environment are recommended. Teachers should realistically assess their abilities and career prospects. (AM)

  10. Angle-tip Fiber Probe as Humidity Sensor

    Directory of Open Access Journals (Sweden)

    Pabitra NATH

    2010-05-01

    Full Text Available In this paper, I present a simple fiber optic relative humidity sensor (FORHS using an angled-tip multimode optical fiber. The sensing region is fabricated by coating moisture sensitive Cobalt Chloride (CoCl2 doped polyvinyl alcohol (PVA film on the surface of fiber optic tip. Light signal introducing from flat-end of the fiber is back-reflected at the fiber tip-air interface by the effect of total internal refection. The change of relative humidity (RH in the outstanding medium affects of evanescent field absorption at the fiber tip-sensing film interface thus, modulates the back-reflected signal. With the present sensing investigation, RH ranging from 5 % to 95 % can be measured with high degree of repeatability and has a fast response time of about 2 seconds.

  11. Pre-Liver Transplant: Tips Versus Distal Splenorenal Shunt

    Directory of Open Access Journals (Sweden)

    Thomas W. Faust

    1997-01-01

    Full Text Available Recurrent variceal bleeding in liver transplant candidates with end-stage liver disease can complicate or even prohibit a subsequent transplant procedure (OLT. Endoscopic sclero-therapy and medical therapy are considered as first-line management with surgical shunts reserved for refractory situations. Surgical shunts can be associated with a high mortality in this population and may complicate subsequent OLT. The transjugular intrahepatic portosystemic shunt (TIPS has been recommended in these patients as a bridge to OLT. This is a new modality that has not been compared with previously established therapies such as the distal splenorenal shunt (DSRS. In this study we report our experience with 35 liver transplant recipients who had a previous TIPS (18 patients or DSRS (17 patients for variceal bleeding. The TIPS group had a significantly larger proportion of critically ill and Child-Pugh C patients. Mean operating time was more prolonged in the DSRS group (P=0.014 but transfusion requirements were similar. Intraoperative portal vein blood flow measurements averaged 2132±725 ml/min in the TIPS group compared with 1120±351ml/min in the DSRS group (P<0.001. Arterial flows were similar. Mean ICU and hospital stays were similar. There were 3 hospital mortalities in the DSRS group and none in the TIPS group (P=0.1. We conclude that TIPS is a valuable tool in the management of recurrent variceal bleeding prior to liver transplantation. Intra0Perative hemodynamic measurements suggest a theoretical advantage with TIPS. In a group of patients with advanced liver disease we report an outcome that is similar to patients treated with DSRS prior to liver transplantation. The role of TIPS in the treatment of nontransplant candidates remains to be clarified.

  12. Tip Vortex Index (TVI) Technique for Inboard Propeller Noise Estimation

    OpenAIRE

    Sezen, Savaş; Dogrul, Ali; Bal, Şakir

    2018-01-01

    Cavitating marine propeller is one of the most dominant noise sources inmarine vessels.  The aim of this study isto examine the cavitating propeller noise induced by tip vortices for twinscrew passenger vessels. To determine the noise level inboard, tip vortex index(TVI) technique has been used. This technique is an approximate method based onnumerical and experimental data. In this study, it is aimed to predict theunderwater noise of a marine propeller by applying TVI technique for ...

  13. Performance study of quadrupole with broken line profile pole tip

    International Nuclear Information System (INIS)

    Fan Mingwu; Zhang Tianjue; Chu Chengjie

    1997-01-01

    Most of quadrupole used for beam focusing possess hyperbola profile tip. To simplify machining processes and ensure the assembling accuracy, a broken line profile pole tip is adapted instead of hyperbola. The results of the magnetic field simulation codes and the tests show the good quality field generated by such configuration: not only more uniform field gradient, but also field more concentrated at useful area. These types of quadrupole are used at CYCIAE-30 cyclotron and HI-13 tandem transportation lines

  14. [Tips to activate your laboratory technologists].

    Science.gov (United States)

    Kimura, Satoshi

    2009-01-01

    For about two decades, Japanese clinical laboratories have been suffering depression because of the government policy to reduce medical expenditure. Here are my proposals to re-vitalize laboratory science in Japan. (1) Do not keep laboratory technologists stay inside laboratories. Take them out to bedside to show what is going on. Show your technologists' face to medical professionals to experience clinical demand. (2) Invite doctors who cared severely ill patients to your laboratory. Every month my laboratory holds case study meetings using electronic medical records (EMR). Doctors and residents present how laboratory data saved the patient's life. Attending the meeting, laboratory technologists realize how they contributed to improve the patients' destiny. This "case study meeting" with EMR stimulates laboratory technologists to understand they are really one of major players in dramatic story of clinical medicine. (3) Establish a sophisticated industry of biotechnology. Populations of senior citizens are growing in all the developed nations in the world. The healthcare demand is very likely to increase. Because Japan is experiencing "aging society" most drastically, the Japanese could get the first major chance to develop new technologies to improve senior citizens' quality of life. The more government reduce medical expenditure, the less healthcare industry grows up. Without major biotechnology industry, the Japanese have to import expensive technologies from overseas. In conclusion, Japanese society of laboratory medicine, together with related industries should get united to appeal how they can contribute to the nation, in order to obtain appropriate fee, as an investment for future people's health.

  15. Surface elevation changes of the greenland ice sheet - results from ESA'S ice sheet CCI

    DEFF Research Database (Denmark)

    Fredenslund Levinsen, Joanna; Khvorostovky, Kirill; Meister, Rakia

    2013-01-01

    In order to ensure long-term climate data records for the Greenland Ice Sheet (GIS), ESA have launched the Climate Change Initiative (CCI). This work presents the preliminary steps towards the Ice Sheet CCI's surface elevation change (SEC) derivation using radar altimeter data. In order to find...

  16. Comparison of manufacturing of lightweight corrugated sheet sandwiches by hydroforming and incremental sheet forming

    Science.gov (United States)

    Maqbool, Fawad; Elze, Lars; Seidlitz, Holger; Bambach, Markus

    2016-10-01

    Sandwich materials made from corrugated sheet metal provide excellent mechanical properties for lightweight design without using filler material. The increased mechanical properties of these sandwich materials are achieved by the 3-D geometry of the corrugated sheet and the hardening due to pre-forming. In the present study, manufacturing of corrugated sheet metal consisting of hexagonal bulge patterns through hydroforming and incremental forming is analyzed. Double layered corrugated sheet metal sandwiches with hexagonal patterns of free-form bulge geometries are investigated through finite element analysis for the maximum increase in stiffness over the normal flat sheets. The analysis shows that a bending stiffness increase of up to 13 times over flat sheet of the same mass is attainable by corrugated sandwiches. Further, it is proved for these types of corrugation sandwiches that stiffness increases by increasing the height of the corrugation bulge but that hydroforming poses restrictions with respect to bulge height, since it is limited by forming force and formability of the material. Incremental sheet metal forming can be used to produce sheets with a hexagonal bulge pattern with increased height. Hence, a higher increase in stiffness as compared to hydroforming is possible but at the expense of process speed.

  17. Surface elevation changes of the greenland ice sheet - results from ESA'S ice sheet CCI

    DEFF Research Database (Denmark)

    Fredenslund Levinsen, Joanna; Khvorostovky, Kirill; Meister, Rakia

    2013-01-01

    In order to ensure long-term climate data records for the Greenland Ice Sheet (GIS), ESA have launched the Climate Change Initiative (CCI). This work presents the preliminary steps towards the Ice Sheet CCI's surface elevation change (SEC) derivation using radar altimeter data. In order to find t...

  18. Evaluation of the safety and efficiency of novel metallic ultrasonic scaler tip on titanium surfaces.

    Science.gov (United States)

    Baek, Seung-Ho; Shon, Won-Jun; Bae, Kwang-Shik; Kum, Kee-Yeon; Lee, Woo-Cheol; Park, Young-Seok

    2012-11-01

    To evaluate the safety and efficiency of novel ultrasonic scaler tips, conventional stainless-steel tips, and plastic tips on titanium surfaces. Mechanical instrumentation was carried out using conventional ultrasonic scalers (EMS, Nyon, Switzerland) with novel metallic implant tip (BS), a plastic-headed tip (ES), a plastic tip (PS) and a conventional stainless-steel tip (CS) on 10 polished commercially pure titanium disks (Grade II) per group. Arithmetic mean roughness (R(a) ) and maximum height roughness (R(y) ) of titanium samples were measured and dissipated power of the scaler tip in the tip-surface junction was estimated to investigate the scaling efficiency. The instrumented surface morphology of samples was viewed with a scanning electron microscope (SEM) and surface profile of the each sample was investigated using contact mode with a commercial atomic force microscope (AFM). There were no significant differences in surface roughness (R(a) and R(y) ) among BS, ES, and PS group. However, CS group showed significant higher surface roughness (R(a) and R(y) ). The efficiency of CS tip is twice as much higher than that of BS tip, the efficiency of BS tip is 20 times higher than that of PS tip, and the efficiency of BS tip is 90 times higher than that of ES tip. Novel metallic copper alloy ultrasonic scaler tips may minimally influence the titanium surface, similar to plastic tip. Therefore, they can be a suitable instrument for implant maintenance therapy. © 2011 John Wiley & Sons A/S.

  19. Pregnancy and Medicines

    Science.gov (United States)

    Not all medicines are safe to take when you are pregnant. Some medicines can harm your baby. That includes over-the- ... care provider before you start or stop any medicine. Not using medicine that you need may be ...

  20. Buying & Using Medicine Safely

    Science.gov (United States)

    ... health professionals to make the best medicine choices, buy safely, and use medicine so it's as safe ... Antibiotics and Antibiotic Resistance Buying Medicines Over the Internet BeSafeRx: Know Your Online Pharmacy Buying Medicine from ...