14 CFR 61.96 - Applicability and eligibility requirements: General.

Science.gov (United States)

2010-01-01

... certificate must: (1) Be at least 17 years of age; (2) Be able to read, speak, write, and understand the English language. If the applicant is unable to meet one of these requirements due to medical reasons... authorized instructor who— (i) Conducted the training or reviewed the applicant's home study on the...

Generation of high brightness x-ray source and its medical applications

International Nuclear Information System (INIS)

Fujii, Sadao; Muro, Mikio; Oku, Yasunari; Daido, Hiroyuki; Takahashi, Kenjiro

2001-01-01

Laser produced plasmas are one of the most feasible sources to be used for industrial applications, especially medical applications: Angiography, Protein crystallography, X-ray microscopy and XAFS. In the present paper, laser requirements are clarified for the medical and life science fields and then we estimate both the photon energy spectra and the number of photons based on Monte-Carlo simulation. (author)

Trusted data management for Grid-based medical applications

NARCIS (Netherlands)

van 't Noordende, G.J.; Olabarriaga, S.D.; Koot, M.R.; de Laat, C.T.A.M.; Udoh, E.

2011-01-01

Existing Grid technology has been foremost designed with performance and scalability in mind. When using Grid infrastructure for medical applications, privacy and security considerations become paramount. Privacy aspects require a re-thinking of the design and implementation of common Grid

Applications of computational tools in biosciences and medical engineering

CERN Document Server

Altenbach, Holm

2015-01-01

 This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

Human rights and the requirement for international medical aid.

Science.gov (United States)

Tolchin, Benjamin

2008-08-01

Every year approximately 18 million people die prematurely from treatable medical conditions including infectious diseases and nutritional deficiencies. The deaths occur primarily amongst the poorest citizens of poor developing nations. Various groups and individuals have advanced plans for major international medical aid to avert many of these unnecessary deaths. For example, the World Health Organization's Commission on Macroeconomics and Health estimated that eight million premature deaths could be prevented annually by interventions costing roughly US$57 bn per year. This essay advances an argument that human rights require high-income nations to provide such aid. The essay briefly examines John Rawls' obligations of justice and the reasons that their applicability to cases of international medical aid remains controversial. Regardless, the essay argues that purely humanitarian obligations bind the governments and citizens of high-income liberal democracies at a minimum to provide major medical aid to avert premature deaths in poor nations. In refusing to undertake such medical relief efforts, developed nations fail to adequately protect a fundamental human right to life.

Pre-Medical Preparation in Microbiology among Applicants and Matriculants in Osteopathic Medical School in the United States.

Science.gov (United States)

Ramos, Raddy L; Guercio, Erik; Martinez, Luis R

2017-01-01

It is recognized that medical school curricula contain significant microbiology-related content as part of the training of future physicians who will be responsible stewards of antimicrobials. Surprisingly, osteopathic and allopathic medical schools do not require pre-medical microbiology coursework, and the extent to which medical students have completed microbiology coursework remains poorly understood. In this report, we show that fewer than 3% of applicants and matriculants to osteopathic medical school (OMS) have completed an undergraduate major or minor in microbiology, and fewer than 17% of applicants and matriculants to OMS have completed one or more microbiology-related courses. These data demonstrate limited pre-medical microbiology-related knowledge among osteopathic medical students, which may be associated with an increase in perceived stress when learning this content or during clinical rotations as well as a potential lack of interest in pursuing a career in infectious diseases.

Identification and Evaluation of Medical Translator Mobile Applications Using an Adapted APPLICATIONS Scoring System.

Science.gov (United States)

Khander, Amrin; Farag, Sara; Chen, Katherine T

2017-12-22

With an increasing number of patients requiring translator services, many providers are turning to mobile applications (apps) for assistance. However, there have been no published reviews of medical translator apps. To identify and evaluate medical translator mobile apps using an adapted APPLICATIONS scoring system. A list of apps was identified from the Apple iTunes and Google Play stores, using the search term, "medical translator." Apps not found on two different searches, not in an English-based platform, not used for translation, or not functional after purchase, were excluded. The remaining apps were evaluated using an adapted APPLICATIONS scoring system, which included both objective and subjective criteria. App comprehensiveness was a weighted score defined by the number of non-English languages included in each app relative to the proportion of non-English speakers in the United States. The Apple iTunes and Google Play stores. Medical translator apps identified using the search term "medical translator." Main Outcomes and Measures: Compilation of medical translator apps for provider usage. A total of 524 apps were initially found. After applying the exclusion criteria, 20 (8.2%) apps from the Google Play store and 26 (9.2%) apps from the Apple iTunes store remained for evaluation. The highest scoring apps, Canopy Medical Translator, Universal Doctor Speaker, and Vocre Translate, scored 13.5 out of 18.7 possible points. A large proportion of apps initially found did not function as medical translator apps. Using the APPLICATIONS scoring system, we have identified and evaluated medical translator apps for providers who care for non-English speaking patients.

When Might Sunburn Require Medical Attention?

Science.gov (United States)

... need medical attention? When might sunburn require medical attention? Answers from Lawrence E. Gibson, M.D. Consult ... of Privacy Practices Notice of Nondiscrimination Manage Cookies Advertising Mayo Clinic is a not-for-profit organization ...

Extracurricular activities of medical school applicants

Directory of Open Access Journals (Sweden)

Sang Hyun Kim

2016-06-01

Full Text Available Purpose: The purpose of this study was to investigate medical school applicants’ involvements in extracurricular activities including medical volunteering/community services, nonmedical community services, club activities, leadership role, and research. Methods: Extracurricular characteristics were compared for 448 applicants (223 males and 225 females who applied to Kangwon Medical School in 2013 to 2014. Frequency analysis, chi-square test, and simple correlation were conducted with the collected data. Results: The 448 applicants participated in medical volunteer/community services (15.3%, nonmedical community services (39.8%, club activities (22.9%, club officials (10%, and research (13.4%. On average, applicants from foreign universities participated in 0.9 medical volunteer/community service, 0.8 nonmedical community service, 1.7 club activities, and 0.6 research work. On the other hand, applicants from domestic universities reported 0.2 medical volunteer/community service, 1.0 nonmedical community service, 0.7 club activity, and 0.3 research. Conclusion: Involvement in extracurricular activities was extensive for medical school applicants. Participation in extracurricular activities differed between applicants from foreign and domestic universities. Females consistently reported greater participation in extracurricular activities than males. The data can be helpful for admission committees to recruit well-rounded applicants and compare between applicants with similar academic backgrounds.

76 FR 71577 - Guidance for Industry on Medication Guide Distribution Requirements and Inclusion of Medication...

Science.gov (United States)

2011-11-18

...] Guidance for Industry on Medication Guide Distribution Requirements and Inclusion of Medication Guides in... guidance for industry entitled ``Medication Guides-- Distribution Requirements and Inclusion in Risk... Requirements and Inclusion in Risk Evaluation and Mitigation Strategies (REMS).'' This guidance provides...

Photon and electron interaction databases and their use in medical applications

International Nuclear Information System (INIS)

Cullen, D.E.

1994-05-01

This paper discusses the All Particle-Method photon and electron interaction, and atomic relaxation data bases, that were initially developed for use in medical applications. Currently these data bases are being used in both medical and industrial applications. The All Particle Method data bases are designed to allow modelling of individual collisions in as much detail as possible. Elastic scattering can be modelled as single, as opposed to multiple, scattering events. Ionization can be modelled at the atomic subshell level, to define which subshell was ionized, spectrum of the initially emitted electron, as well as the spectra of electron and photons emitted as the atom relaxes back to neutrality. These data bases are currently being used in applications involving rather small spatial regions, where detailed calculations of individual events are required. While initially designed for use in medical applications, these data bases are now being used in a variety of industrial applications, e.g., transport in microelectronics

The FLUKA Code: Developments and Challenges for High Energy and Medical Applications

CERN Document Server

Böhlen, T T; Chin, M P W; Fassò, A; Ferrari, A; Ortega, P G; Mairani, A; Sala, P R; Smirnov, G; Vlachoudis, V

2014-01-01

The FLUKA Monte Carlo code is used extensively at CERN for all beam-machine interactions, radioprotection calculations and facility design of forthcoming projects. Such needs require the code to be consistently reliable over the entire energy range (from MeV to TeV) for all projectiles (full suite of elementary particles and heavy ions). Outside CERN, among various applications worldwide, FLUKA serves as a core tool for the HIT and CNAO hadron-therapy facilities in Europe. Therefore, medical applications further impose stringent requirements in terms of reliability and predictive power, which demands constant refinement of sophisticated nuclear models and continuous code improvement. Some of the latest developments implemented in FLUKA are presented in this paper, with particular emphasis on issues and concerns pertaining to CERN and medical applications.

CERN's role in medical applications

CERN Multimedia

Antonella Del Rosso

2014-01-01

Last week, CERN hosted the first meeting of the International Strategy Committee for medical applications. This Committee will help CERN establish its roadmap in the field of research and development activities for medical applications. Here the CERN Bulletin speaks with the Chair of the Committee as he shares his expectations and his vision.   Dr Michael Baumann is the Director of the Radiation Oncology department at the Carl Gustav Carus University Hospital in Dresden and of the Institute for Radiooncology of the Helmholtz-Zentrum Dresden-Rossendorf (Germany). He has recently been appointed Chair of CERN’s International Strategy Committee for medical applications – the team of experts who will advise the CERN Medical Applications Study Group led by Steve Myers. “CERN has a tremendous record in physics and basic research,” says Baumann. “I think that it has a very important role in steering some of the R&D that cannot be done at universities ...

Datenschutz- und Medizinprodukterecht bei Ubiquitous Computing-Anwendungen im Gesundheitssektor / Data protection and medical product law with respect to medical ubiquitous computing applications

Directory of Open Access Journals (Sweden)

Skistims, Hendrik

2011-01-01

Full Text Available With respect to ubiquitous computing there is a great potential of application, particularly in medicine and health care. This work deals with the legal problems which ubiquitous computing is facing in these areas. At the beginning, issues with respect to data protection and professional secrecy are treated. Afterwards the problem of applicability of medical product law for medical ubiquitous computing applications as well as the resulting requirements for manufactures, operators and users will be discussed.

Medical physics personnel for medical imaging: requirements, conditions of involvement and staffing levels-French recommendations

International Nuclear Information System (INIS)

Isambert, Aurelie; Valero, Marc; Rousse, Carole; Blanchard, Vincent; Le Du, Dominique; Guilhem, Marie-Therese; Dieudonne, Arnaud; Pierrat, Noelle; Salvat, Cecile

2015-01-01

The French regulations concerning the involvement of medical physicists in medical imaging procedures are relatively vague. In May 2013, the ASN and the SFPM issued recommendations regarding Medical Physics Personnel for Medical Imaging: Requirements, Conditions of Involvement and Staffing Levels. In these recommendations, the various areas of activity of medical physicists in radiology and nuclear medicine have been identified and described, and the time required to perform each task has been evaluated. Criteria for defining medical physics staffing levels are thus proposed. These criteria are defined according to the technical platform, the procedures and techniques practised on it, the number of patients treated and the number of persons in the medical and paramedical teams requiring periodic training. The result of this work is an aid available to each medical establishment to determine their own needs in terms of medical physics. (authors)

Radiation protection in medical applications

International Nuclear Information System (INIS)

Maldonado M, H.

2008-12-01

The justification of the practices is the fundamental principle on which rests the peaceful use of ionizing radiations. They actually contain as aspirations to improve the quality of people's lives, contributing to sustainable development through environmental protection, so that the sources security and the individuals protection will be conditions which are not and should can not be operated. For medical applications is a highly illustrative example of this, since both for the diagnosis and therapy, the goal is to achieve what is sought for the white tissue, secured the least possible damage to the neighboring tissues so that in turn reduce the negative effects for the patient. As a basis for achieving the above, it is essential to have qualified personnel in all areas incidents, for example users, workers, officials and staff members. There are a variety of specialists in the field of medical applications as, nuclear chemistry, nuclear engineering, radiation protection, medical physics, radiation physics and others. Among the human resource in the country must make up the majority are medical radiologists, highlighting gaps in the number of radiotherapy and nuclear medicine but specially in the medical physics, who is in some way from a special viewpoint of the formal school, new to the country. This is true for the number of facilities which are in the country. The radiation protection responsibilities in medical applications focus primarily on two figures: the radiology safety manager, who is primarily dedicated to the protection of occupationally exposed personnel and the public, and the medical physicist whose functions are geared towards the radiological protection of the patient. The principal legislation in the medical applications area has been enacted and is monitored by the Health Secretary and National Commission on Nuclear Safety and Safeguards, entities that have reached agreements to avoid overlap and over-regulation. Medical applications in the

Some advances in medical applications of low energy accelerators

Science.gov (United States)

Valković, V.; Moschini, G.

1991-05-01

Medical applications of low energy accelerators include: the use of nuclear analytical methods and procedures for laboratory studies and routine measurements; material productions and modifications to meet special requirements; radioisotope productions and their applications in radiopharmaceuticals as well as in positron emission tomography; and radiotherapy with ions, based on improved understanding of the interaction of charged particles with living tissue. Some of the recent advances in these fields are critically summarized. The plan for an improved charged particle facility in a hospital environment dedicated to applications in biology and medicine is presented.

Real-time image mosaicing for medical applications.

Science.gov (United States)

Loewke, Kevin E; Camarillo, David B; Jobst, Christopher A; Salisbury, J Kenneth

2007-01-01

In this paper we describe the development of a robotically-assisted image mosaicing system for medical applications. The processing occurs in real-time due to a fast initial image alignment provided by robotic position sensing. Near-field imaging, defined by relatively large camera motion, requires translations as well as pan and tilt orientations to be measured. To capture these measurements we use 5-d.o.f. sensing along with a hand-eye calibration to account for sensor offset. This sensor-based approach speeds up the mosaicing, eliminates cumulative errors, and readily handles arbitrary camera motions. Our results have produced visually satisfactory mosaics on a dental model but can be extended to other medical images.

An overview on extremity dosimetry in medical applications

International Nuclear Information System (INIS)

Vanhavere, F.; Carinou, E.; Donadille, L.; Ginjaume, M.; Jankowski, J.; Rimpler, A.; Sans Merce, M.

2008-01-01

Some activities of EURADOS Working Group 9 (WG9) are presently funded by the European Commission (CONRAD project). The objective of WG9 is to promote and co-ordinate research activities for the assessment of occupational exposures to staff at workplaces in interventional radiology (IR) and nuclear medicine. For some of these applications, the skin of the fingers is the limiting organ for individual monitoring of external radiation. Therefore, sub-group 1 of WG9 deals with the use of extremity dosemeters in medical radiation fields. The wide variety of radiation field characteristics present in a medical environment together with the difficulties in measuring a local dose that is representative for the maximum skin dose, usually with one single detector, makes it difficult to perform accurate extremity dosimetry. Sub-group 1 worked out a thorough literature review on extremity dosimetry issues in diagnostic and therapeutic nuclear medicine and positron emission tomography, interventional radiology and interventional cardiology and brachytherapy. Some studies showed that the annual dose limits could be exceeded if the required protection measures are not taken, especially in nuclear medicine. The continuous progress in new applications and techniques requires an important effort in radiation protection and training. (authors)

Medical physics personnel for medical imaging: requirements, conditions of involvement and staffing levels-French recommendations.

Science.gov (United States)

Isambert, Aurélie; Le Du, Dominique; Valéro, Marc; Guilhem, Marie-Thérèse; Rousse, Carole; Dieudonné, Arnaud; Blanchard, Vincent; Pierrat, Noëlle; Salvat, Cécile

2015-04-01

The French regulations concerning the involvement of medical physicists in medical imaging procedures are relatively vague. In May 2013, the ASN and the SFPM issued recommendations regarding Medical Physics Personnel for Medical Imaging: Requirements, Conditions of Involvement and Staffing Levels. In these recommendations, the various areas of activity of medical physicists in radiology and nuclear medicine have been identified and described, and the time required to perform each task has been evaluated. Criteria for defining medical physics staffing levels are thus proposed. These criteria are defined according to the technical platform, the procedures and techniques practised on it, the number of patients treated and the number of persons in the medical and paramedical teams requiring periodic training. The result of this work is an aid available to each medical establishment to determine their own needs in terms of medical physics. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Medical applications of accelerators

CERN Document Server

Rossi, Sandro

1998-01-01

At Present, about five thousands accelerators are devoted to biomedical applications. They are mainly used in radiotherapy, research and medical radioisotopes production. In this framework oncological hadron-therapy deserves particular attention since it represents a field in rapid evolution thanks to the joint efforts of laboratories with long experiences in particle physics. It is the case of CERN where the design of an optimised synchrotron for medical applications has been pursued. These lectures present these activities with particular attention to the new developments which are scientifically interesting and/or economically promising.

Security issues in healthcare applications using wireless medical sensor networks: a survey.

Science.gov (United States)

Kumar, Pardeep; Lee, Hoon-Jae

2012-01-01

Healthcare applications are considered as promising fields for wireless sensor networks, where patients can be monitored using wireless medical sensor networks (WMSNs). Current WMSN healthcare research trends focus on patient reliable communication, patient mobility, and energy-efficient routing, as a few examples. However, deploying new technologies in healthcare applications without considering security makes patient privacy vulnerable. Moreover, the physiological data of an individual are highly sensitive. Therefore, security is a paramount requirement of healthcare applications, especially in the case of patient privacy, if the patient has an embarrassing disease. This paper discusses the security and privacy issues in healthcare application using WMSNs. We highlight some popular healthcare projects using wireless medical sensor networks, and discuss their security. Our aim is to instigate discussion on these critical issues since the success of healthcare application depends directly on patient security and privacy, for ethic as well as legal reasons. In addition, we discuss the issues with existing security mechanisms, and sketch out the important security requirements for such applications. In addition, the paper reviews existing schemes that have been recently proposed to provide security solutions in wireless healthcare scenarios. Finally, the paper ends up with a summary of open security research issues that need to be explored for future healthcare applications using WMSNs.

Security Issues in Healthcare Applications Using Wireless Medical Sensor Networks: A Survey

Directory of Open Access Journals (Sweden)

Hoon-Jae Lee

2011-12-01

Full Text Available Healthcare applications are considered as promising fields for wireless sensor networks, where patients can be monitored using wireless medical sensor networks (WMSNs. Current WMSN healthcare research trends focus on patient reliable communication, patient mobility, and energy-efficient routing, as a few examples. However, deploying new technologies in healthcare applications without considering security makes patient privacy vulnerable. Moreover, the physiological data of an individual are highly sensitive. Therefore, security is a paramount requirement of healthcare applications, especially in the case of patient privacy, if the patient has an embarrassing disease. This paper discusses the security and privacy issues in healthcare application using WMSNs. We highlight some popular healthcare projects using wireless medical sensor networks, and discuss their security. Our aim is to instigate discussion on these critical issues since the success of healthcare application depends directly on patient security and privacy, for ethic as well as legal reasons. In addition, we discuss the issues with existing security mechanisms, and sketch out the important security requirements for such applications. In addition, the paper reviews existing schemes that have been recently proposed to provide security solutions in wireless healthcare scenarios. Finally, the paper ends up with a summary of open security research issues that need to be explored for future healthcare applications using WMSNs.

The Application of Use Case Modeling in Designing Medical Imaging Information Systems

International Nuclear Information System (INIS)

Safdari, Reza; Farzi, Jebraeil; Ghazisaeidi, Marjan; Mirzaee, Mahboobeh; Goodini, Azadeh

2013-01-01

Introduction. The essay at hand is aimed at examining the application of use case modeling in analyzing and designing information systems to support Medical Imaging services. Methods. The application of use case modeling in analyzing and designing health information systems was examined using electronic databases (Pubmed, Google scholar) resources and the characteristics of the modeling system and its effect on the development and design of the health information systems were analyzed. Results. Analyzing the subject indicated that Provident modeling of health information systems should provide for quick access to many health data resources in a way that patients' data can be used in order to expand distant services and comprehensive Medical Imaging advices. Also these experiences show that progress in the infrastructure development stages through gradual and repeated evolution process of user requirements is stronger and this can lead to a decline in the cycle of requirements engineering process in the design of Medical Imaging information systems. Conclusion. Use case modeling approach can be effective in directing the problems of health and Medical Imaging information systems towards understanding, focusing on the start and analysis, better planning, repetition, and control

21 CFR 515.10 - Medicated feed mill license applications.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Medicated feed mill license applications. 515.10... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Applications § 515.10 Medicated feed mill license applications. (a) Medicated feed mill license applications (Forms FDA 3448) may...

42 CFR 436.811 - Medically needy income standard: General requirements.

Science.gov (United States)

2010-10-01

... THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Income Standard... groups that meets the requirements of this section. (b) The income standard must take into account the... the State's covered medically needy group or groups of individuals under § 436.301. (d) The income...

Graphical User Interfaces for Volume Rendering Applications in Medical Imaging

OpenAIRE

Lindfors, Lisa; Lindmark, Hanna

2002-01-01

Volume rendering applications are used in medical imaging in order to facilitate the analysis of three-dimensional image data. This study focuses on how to improve the usability of graphical user interfaces of these systems, by gathering user requirements. This is achieved by evaluations of existing systems, together with interviews and observations at clinics in Sweden that use volume rendering to some extent. The usability of the applications of today is not sufficient, according to the use...

47 CFR 15.513 - Technical requirements for medical imaging systems.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Technical requirements for medical imaging... DEVICES Ultra-Wideband Operation § 15.513 Technical requirements for medical imaging systems. (a) The UWB... MHz and 10,600 MHz. (b) Operation under the provisions of this section is limited to medical imaging...

Synchrotron radiation applications in medical research

International Nuclear Information System (INIS)

Thomlinson, W.

1995-01-01

The medical projects employing synchrotron radiation as discussed in this paper are, for the most part, still in their infancies and no one can predict the direction in which they will develop. Both the basic research and applied medical programs are sure to be advanced at the new facilities coming on line, especially the ESRF and Spring- 8. However, success is not guaranteed. There is a lot of competition from advances in conventional imaging with the development of digital angiography, computed tomography, functional magnetic resonance imaging and ultrasound. The synchrotron programs will have to provide significant advantages over these modalities in order to be accepted by the medical profession. Advances in image processing and potentially the development of compact sources will be required in order to move the synchrotron developed imaging technologies into the clinical world. In any event, it can be expected that the images produced by the synchrotron technologies will establish ''gold standards'' to be targeted by conventional modalities. A lot more work needs to be done in order to bring synchrotron radiation therapy and surgery to the level of human studies and, subsequently, to clinical applications

Medical leadership: why it's important, what is required, and how we develop it.

Science.gov (United States)

Warren, Oliver J; Carnall, Ruth

2011-01-01

Good medical leadership is vital in delivering high-quality healthcare, and yet medical career progression has traditionally seen leadership lack credence in comparison with technical and academic ability. Individual standards have varied, leading to variations in the quality of medical leadership between different organisations and, on occasions, catastrophic lapses in the standard of care provided to patients. These high-profile events, plus increasing evidence linking clinical leadership to performance of units, has led recently to more focus on leadership development for all doctors, starting earlier and continuing throughout their careers. There is also an increased drive to see doctors take on more significant leadership roles throughout the healthcare system. The achievement of these aims will require doctors to develop strong personal and professional values, a range of non-technical skills that allow them to lead across professional boundaries, and an understanding of the increasingly complex environment in which 21st century healthcare is delivered. Developing these attributes will require dedicated resources and the sophisticated application of a variety of different learning methodologies such as mentoring, coaching, action learning and networking.

State of the art in medical applications using non-thermal atmospheric pressure plasma

Science.gov (United States)

Tanaka, Hiromasa; Ishikawa, Kenji; Mizuno, Masaaki; Toyokuni, Shinya; Kajiyama, Hiroaki; Kikkawa, Fumitaka; Metelmann, Hans-Robert; Hori, Masaru

2017-12-01

Plasma medical science is a novel interdisciplinary field that combines studies on plasma science and medical science, with the anticipation that understanding the scientific principles governing plasma medical science will lead to innovations in the field. Non-thermal atmospheric pressure plasma has been used for medical treatments, such as for cancer, blood coagulation, and wound healing. The interactions that occur between plasma and cells/tissues have been analyzed extensively. Direct and indirect treatment of cells with plasma has broadened the applications of non-thermal atmospheric pressure plasma in medicine. Examples of indirect treatment include plasma-assisted immune-therapy and plasma-activated medium. Controlling intracellular redox balance may be key in plasma cancer treatment. Animal studies are required to test the effectiveness and safety of these treatments for future clinical applications.

[Study of the Application of Mobile Medical Technology in Construction of Grading Diagnosis and Treatment System].

Science.gov (United States)

Zhu, Wenwu; Shen, Yihong; Zhen, Hui; Yang, Xiaohe; Hu, Kai

2018-02-08

The combination of mobile medical technology and the grading diagnosis and treatment system (GDTS) can stimulate the allocation of medical resources, reduce medical cost and improve public health significantly. Firstly we summarize development features of mobile medical technology in foreign and domestic market, then we study the application model of mobile medical application in GDTS with field research data and analyzes its advantage and shortage. Finally, we propose four measures for further developing mobile medical application in the GDTS:the government departments should formulate policies and industry standards of products as soon as possible to meet requirement of market; service providers should take the hospitals as core role to achieve mutual benefit and win-win situation; take the daily monitoring of chronic diseases as an entry point to build profitable business model; enhance publicity to promote public health awareness.

75 FR 52472 - Spectrum Requirements for Advanced Medical Technologies

Science.gov (United States)

2010-08-26

... medical devices. Under this framework, the rules for MedRadio service incorporates the MICS ``core'' band... Requirements for Advanced Medical Technologies AGENCY: Federal Communications Commission. ACTION: Final rule.... (Medtronic) regarding rules for the Medical Device Radiocommunication (MedRadio) service. The Commission...

Radioisotopes for medical applications

International Nuclear Information System (INIS)

Carr, S.

1998-01-01

For more than 3 decades, the Australian Nuclear Science and Technology Organisation has been the country's main supplier of radioisotopes for medical applications. The use of radioisotopes in medicine has revolutionised the diagnosis, management and treatment of many serious diseases such as cancer, heart disease and stroke. It is also beginning to play a key role in neurological disorders such as Parkinson and Alzheimers disease and epilepsy. More recently there has been considerable growth in the application of nuclear medicine to treat sport-related injuries - especially wrist, ankle and knees where more common techniques do not always enable accurate diagnosis. Australia is a recognised leader in nuclear medicine. This can be partially attributed to the close relationship between ANSTO and the medical community in providing opportunities to develop and evaluate new agents to support more effective patient care. A list of commercial isotopes produced in the reactor or the cyclotron and used in medical applications is given. Nuclear medicine plays an important role in the clinical environment and the timely supply of radioisotopes is a key element. ANSTO will continue to be the premier supplier of currently available and developing isotopes to support the health and well being of the Australian community

Radioisotopes for medical applications

Energy Technology Data Exchange (ETDEWEB)

Carr, S. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia). Radiopharmaceuticals Division

1998-03-01

For more than 3 decades, the Australian Nuclear Science and Technology Organisation has been the country`s main supplier of radioisotopes for medical applications. The use of radioisotopes in medicine has revolutionised the diagnosis, management and treatment of many serious diseases such as cancer, heart disease and stroke. It is also beginning to play a key role in neurological disorders such as Parkinson and Alzheimers disease and epilepsy. More recently there has been considerable growth in the application of nuclear medicine to treat sport-related injuries - especially wrist, ankle and knees where more common techniques do not always enable accurate diagnosis. Australia is a recognised leader in nuclear medicine. This can be partially attributed to the close relationship between ANSTO and the medical community in providing opportunities to develop and evaluate new agents to support more effective patient care. A list of commercial isotopes produced in the reactor or the cyclotron and used in medical applications is given. Nuclear medicine plays an important role in the clinical environment and the timely supply of radioisotopes is a key element. ANSTO will continue to be the premier supplier of currently available and developing isotopes to support the health and well being of the Australian community 2 tabs., 1 fig.

21 CFR 558.4 - Requirement of a medicated feed mill license.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Requirement of a medicated feed mill license. 558... Provisions § 558.4 Requirement of a medicated feed mill license. (a) A feed manufacturing facility must possess a medicated feed mill license in order to manufacture a Type B or Type C medicated feed from a...

Quality assurance in medical radiation applications. The medical and dental appointment

International Nuclear Information System (INIS)

Ernst-Elz, Andreas

2017-01-01

Medical radiation applications cause averaged over the German population an annual exposure of almost 2 mSv. Medical authorities have the assignment to assure and control the diagnostic and therapeutic quality of these applications and to provide recommendations for operators with respect to dose reductions and radiation protection, including guidance for radiotherapy planning aimed to questions of dose and therapy optimization.

Perception Towards the Use of Smartphone Application (Apps to Enhance Medication Adherence Among Saudi Pediatrics

Directory of Open Access Journals (Sweden)

Renad Alsalamah

2018-03-01

Full Text Available Objectives: The aim of this study was to measure the importance of smartphone applications (Apps in medication adherence in children to help parents and caregivers in giving medication to children to maintain a good health and quality of life, and to improve current clinical practices in adherence to medications among Saudi pediatrics. Methodology: Cross sectional survey to Saudi Arabia population was conducted from March to April 2017(n=405. Data were collected, tabulated and analyzed using Survey Monkey. We present design requirements for building medication reminders that support the routine aspect of medication-taking by linking children’s concerns, (such as games on taking medications at time. Results: Of the 405 survey participants, the majority of participants 72.5% were not aware by applications of smart device that make easier to take medicines regularly. Eighty percent of participants preferred a mobile app to help their children take the medicine easily and regularly, and 39.8% of them thought that the child will interact with this game, the majority of them 88.6% don’t have any obstacle hinders the use of these updated applications. Fifty percent of them will encourage young patients, to use such applications (App to help them in their medication adherence. Conclusion: Nonadherence to medication is still represents a fundamental health care challenge. The presence of an application makes it easier for parents to give medication to their sick children. Most children love playing games, there is a high probability of their attachment to this application (App and it will promote children’s medication adherence. Key words: Patient adherence, Pediatric, Smartphone, Applications, Apps.

Radiation protection in medical applications

International Nuclear Information System (INIS)

Sacc, R.A.; Rubiolo, J.; Herrero, F.

1998-01-01

Full text: The goal of this paper is to identify the areas in which radiation protection is actually needed and the relative importance of protection measures. A correlation between the different medical applications of the ionizing radiations and the associated risks, mainly due to ignorance, has been a constant throughout the history of mankind. At the beginning, the accidents were originated in research nuclear laboratories working on the atomic bomb, while the incidents occurred in medical areas because of virtual ignorance of the harmful effects on humans. The 60's were characterized by the oil fever, which produced innumerable accidents due to the practice of industrial radiography; in the 70's the use of radiations on medical applications was intensified, to such and extent that a new type of victim appeared: the patient. Unfortunately, during 80's and 90's the number of accidents in different medical practices has increased, projecting the occurred in Zaragoza (Spain) on 1990 with a linear accelerator for radiotherapy treatments. In some developed countries, foreseeing the probability of producing biological effects as a result of different radiology practices, more strict security rules are adopted to guarantee the application of the three principles of the radioprotection: justification, optimization and limitation of individual dose. In this way, in the U.S.A., the Joint Commission on Accreditation of Health Care Organization (JCAHO), favors a vigilance politics in the different departments of Radiodiagnostic and Nuclear Medicine to secure an effective management in security, communications and quality control, in which the medical physicists play an important role. One of the requirements for example is to attach the value of entrance exposition dose in the radiological diagnostic report. So, the doses in the different organs are compared with the tabulated doses. Basically, a quality control programme is designed to minimize the risks for patients

Open-source software platform for medical image segmentation applications

Science.gov (United States)

Namías, R.; D'Amato, J. P.; del Fresno, M.

2017-11-01

Segmenting 2D and 3D images is a crucial and challenging problem in medical image analysis. Although several image segmentation algorithms have been proposed for different applications, no universal method currently exists. Moreover, their use is usually limited when detection of complex and multiple adjacent objects of interest is needed. In addition, the continually increasing volumes of medical imaging scans require more efficient segmentation software design and highly usable applications. In this context, we present an extension of our previous segmentation framework which allows the combination of existing explicit deformable models in an efficient and transparent way, handling simultaneously different segmentation strategies and interacting with a graphic user interface (GUI). We present the object-oriented design and the general architecture which consist of two layers: the GUI at the top layer, and the processing core filters at the bottom layer. We apply the framework for segmenting different real-case medical image scenarios on public available datasets including bladder and prostate segmentation from 2D MRI, and heart segmentation in 3D CT. Our experiments on these concrete problems show that this framework facilitates complex and multi-object segmentation goals while providing a fast prototyping open-source segmentation tool.

Seminar Pediatrics. Medical and Technical Applications

International Nuclear Information System (INIS)

Montivero, M.; Nespral, D.O.; Alak, Maria del Carmen

2012-01-01

The Association of Biology and Nuclear Medicine has organized the 'Seminar Pediatrics - Medical and Technical Applications', held in Buenos Aires in May 2012, in order to collaborate with the scientific growth of nuclear medicine in pediatrics. The main topics covered were: management of pediatric patients and medical application in childhood, dosimetry in pediatric nuclear medicine, scope of radioisotope - studies in nephrourological pathologies, PET in pediatrics, among others.

Modeling Medical Services with Mobile Health Applications

Directory of Open Access Journals (Sweden)

Zhenfei Wang

2018-01-01

Full Text Available The rapid development of mobile health technology (m-Health provides unprecedented opportunities for improving health services. As the bridge between doctors and patients, mobile health applications enable patients to communicate with doctors through their smartphones, which is becoming more and more popular among people. To evaluate the influence of m-Health applications on the medical service market, we propose a medical service equilibrium model. The model can balance the supply of doctors and demand of patients and reflect possible options for both doctors and patients with or without m-Health applications in the medical service market. In the meantime, we analyze the behavior of patients and the activities of doctors to minimize patients’ full costs of healthcare and doctors’ futility. Then, we provide a resolution algorithm through mathematical reasoning. Lastly, based on artificially generated dataset, experiments are conducted to evaluate the medical services of m-Health applications.

Medical isotope applications in Iceland

Energy Technology Data Exchange (ETDEWEB)

NONE

1962-10-15

About $ 12 000 worth of equipment and the services of an expert in the medical applications of radioisotopes were provided by IAEA to the Government of Iceland. The expert was primarily concerned with the establishment of a medical radioisotope laboratory at the State Hospital, Reykjavik. His specific tasks included the setting up of the equipment furnished by IAEA for radioactive measurements in medical work, the establishment of techniques for the routine uses of radioisotopes in medicine, and the training of personnel. The apparatus installed includes a well-type scintillation counter for small samples, a directional scintillation counter, and Geiger counters of different types. The laboratory is thus well equipped for nearly all the conventional applications of radioisotopes in medicine, except those involving very soft beta-ray emitting isotopes

Application of the ICRP recommendations in medical radiation practice and in medical monitoring of workers

International Nuclear Information System (INIS)

Lafontaine, A.

1979-01-01

Medical exposure in connection with an existing or suspected illness may be made subject to the ICRP principles, but it must be realized that the dose limitation system cannot necessarily be applied when the individual at risk is the one benefiting from examination or treatment. Justification is the responsibility of the doctor prescribing the examination or treatment and/or of the person carrying it out. Optimization will be achieved by virtue of the rules imposed on doctors and by the requirements applicable to equipment and techniques. The same rules and requirements apply mutatis mutandis to check-ups, routine medical examinations, examinations for professional purposes, medico-legal examinations and medical research. In the last case ethical rules and criteria for the validity of the proposed research also need to be applied. Medical monitoring of workers must take the ICRP principles into account, but a qualified doctor should nevertheless be able to form his own judgement on the basis of his knowledge of different types of exposure (both to radiation and to other agents), to intervene in cases of accidental or planned exposure, and to gather data in order to evaluate the long-term effects and the consequences of occupational exposure in terms of doses to the public. Moreover, the doctor should inform the worker of his conclusions and recommendations. (author)

22 CFR 41.108 - Medical examination.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Medical examination. 41.108 Section 41.108... AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

Deaf mobile application accessibility requirements

Science.gov (United States)

Nathan, Shelena Soosay; Hussain, Azham; Hashim, Nor Laily

2016-08-01

Requirement for deaf mobile applications need to be analysed to ensure the disabilities need are instilled into the mobile applications developed for them. Universal design is understandable to comply every user needs, however specific disability is argued by the authors to have different need and requirements. These differences are among the reasons for these applications being developed to target for a specific group of people, however they are less usable and later abandoned. This study focuses on deriving requirements that are needed by the deaf in their mobile applications that are meant specifically for them. Studies on previous literature was conducted it can be concluded that graphic, text, multimedia and sign language interpreter are among mostly required features to be included in their mobile application to ensure the applications are usable for this community.

28 CFR 90.14 - Forensic medical examination payment requirement.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Forensic medical examination payment... Program § 90.14 Forensic medical examination payment requirement. (a) For the purpose of this subpart B, a... entity incurs the full out-of-pocket costs of forensic medical examinations for victims of sexual assault...

Medical applications in a nuclear research centre

International Nuclear Information System (INIS)

Vanhavere, F.; Eggermont, G.

2001-01-01

In these days of public aversion to nuclear power, it can be important to point at the medical applications of ionising radiation. Not only the general public, but also the authorities and research centres have to be aware of these medical applications, which are not without risk for public health. Now that funding for nuclear research is declining, an opening to the medical world can give new opportunities to a nuclear research centre. A lot of research could be done where the tools developed for the nuclear power world are very useful. Even new applications for the research reactors like BNCT (boron neutron capture therapy) can be envisaged for the near future. In this contribution an overview will be given of the different techniques used in the medical world with ionising radiation. The specific example of the Belgian Nuclear Research Centre will be given where the mission statement was changed to include a certain number of medical research topics. (authors)

Applications of Particle Accelerators in Medical Physics

CERN Document Server

Cuttone, G

2008-01-01

Particle accelerators are often associated to high energy or nuclear physics. As well pointed out in literature [1] if we kindly analyse the number of installation worldwide we can easily note that about 50% is mainly devoted to medical applications (radiotherapy, medical radioisotopes production, biomedical research). Particle accelerators are also playing an important indirect role considering the improvement of the technical features of medical diagnostic. In fact the use of radionuclide for advanced medical imaging is strongly increasing either in conventional radiography (CT and MRI) and also in nuclear medicine for Spect an PET imaging. In this paper role of particle accelerators for medical applications will be presented together with the main solutions applied.

Design Investigation on Applicable Mesh Structures for Medical Stent Applications

Science.gov (United States)

Asano, Shoji; He, Jianmei

2017-11-01

In recent years, utilization of medical stents is one of effective treatments for stenosis and occlusion occurring in a living body’s lumen indispensable for maintenance of human life such as superficial femoral artery (SFA) occlusion. However, there are concerns about the occurrence of fatigue fractures caused by stress concentrations, neointimal hyperplasia and the like due to the shape structure and the manufacturing method in the conventional stents, and a stent having high strength and high flexibility is required. Therefore, in this research, applicable mesh structures for medical stents based on the design concepts of high strength, high flexibility are interested to solve various problem of conventional stent. According to the shape and dimensions of SFA occlusion therapy stent and indwelling delivery catheter, shape design of the meshed stent are performed using 3-dimensional CAD software Solid Works first. Then analytical examination on storage characteristics and compression characteristics of such mesh structure applied stent models were carried out through finite element analysis software ANSYS Workbench. Meshed stent models with higher strength and higher flexibility with integral molding are investigated analytically. It was found that the storage characteristics and compression characteristics of meshed stent modles are highly dependent on the basic mesh shapes with same surface void ratio. Trade-off relationship between flexibility and storage characteristics is found exited, it is required to provide appropriate curvatures during basic mesh shape design.

Indications and the requirements for single-use medical gloves

Science.gov (United States)

Kramer, Axel; Assadian, Ojan

2016-01-01

Aim: While the requirements for single-use gloves for staff protection are clearly defined, the conventional medical differentiation between “sterile surgical gloves” used during surgical procedures and “single-use medical gloves” used in non-sterile medical areas does not adequately define the different requirements in these two areas of use. Sterilization of single-use medical gloves is not performed if sterility is not required; thus, another terminology must be found to identify the safety quality of non-sterile single-use medical gloves. Therefore, the labeling of such gloves should reflect this situation, by introducing the term “pathogen-free” single-use glove. The hygienic safety of such a glove would be attainable by ensuring aseptic manufacturing conditions during manufacturing and control of pathogen load of batch controls after fabrication. Proposed recommendation: Because single-use gloves employed in non-sterile areas come into contact not only with intact skin but also with mucous membranes, no potential pathogens should be detectable in 100 mL of rinse sample. In order to declare such gloves as pathogen-free we suggest absence of the indicator species S. aureus and E. coli. In addition, the total CFU count should be evaluated, since a high load indicates lack of optimal hygiene during the manufacturing process. Based on the requirements for potable water and findings obtained from investigations of the bacterial load of such gloves after manufacturing, the here suggested limit for the total bacterial count of glove seems realistic. PMID:26816673

Application of stereo-imaging technology to medical field.

Science.gov (United States)

Nam, Kyoung Won; Park, Jeongyun; Kim, In Young; Kim, Kwang Gi

2012-09-01

There has been continuous development in the area of stereoscopic medical imaging devices, and many stereoscopic imaging devices have been realized and applied in the medical field. In this article, we review past and current trends pertaining to the application stereo-imaging technologies in the medical field. We describe the basic principles of stereo vision and visual issues related to it, including visual discomfort, binocular disparities, vergence-accommodation mismatch, and visual fatigue. We also present a brief history of medical applications of stereo-imaging techniques, examples of recently developed stereoscopic medical devices, and patent application trends as they pertain to stereo-imaging medical devices. Three-dimensional (3D) stereo-imaging technology can provide more realistic depth perception to the viewer than conventional two-dimensional imaging technology. Therefore, it allows for a more accurate understanding and analysis of the morphology of an object. Based on these advantages, the significance of stereoscopic imaging in the medical field increases in accordance with the increase in the number of laparoscopic surgeries, and stereo-imaging technology plays a key role in the diagnoses of the detailed morphologies of small biological specimens. The application of 3D stereo-imaging technology to the medical field will help improve surgical accuracy, reduce operation times, and enhance patient safety. Therefore, it is important to develop more enhanced stereoscopic medical devices.

Attitudes of Medical Graduate and Undergraduate Students toward the Learning and Application of Medical Statistics

Science.gov (United States)

Wu, Yazhou; Zhang, Ling; Liu, Ling; Zhang, Yanqi; Liu, Xiaoyu; Yi, Dong

2015-01-01

It is clear that the teaching of medical statistics needs to be improved, yet areas for priority are unclear as medical students' learning and application of statistics at different levels is not well known. Our goal is to assess the attitudes of medical students toward the learning and application of medical statistics, and discover their…

A study of RFID application impacts on medical safety.

Science.gov (United States)

Chang, She-I; Ou, Chin-Shyh; Ku, Cheng-Yuan; Yang, Morris

2008-01-01

With the international reform in medical management systems gaining ground worldwide, hospital management has gradually begun to shift its focus from providing expensive medical treatment to improving medical service quality and patient safety. In this study, we discuss the application of Radio Frequency Identification (RFID) and data integrating technology with the medical service, and examine whether or not this technology can enhance medical safety. We also discuss the possible benefits following the application of the RFID system. The findings show that the application of RFID to hospitals can actually generate benefits, which can be further divided into operational structure benefits, users' structure benefits, and organisational and environmental benefits. However, not all these benefits can achieve medical safety. Among them, only the operator and environmental benefits can play such roles. Nevertheless, the application of RFID can bring hospitals towards the integration of technology benefits and improved medical safety.

Contemporary vascular smartphone medical applications.

Science.gov (United States)

Carter, Thomas; O'Neill, Stephen; Johns, Neil; Brady, Richard R W

2013-08-01

Use of smartphones and medical mHealth applications (apps) within the clinical environment provides a potential means for delivering elements of vascular care. This article reviews the contemporary availability of apps specifically themed to major vascular diseases and the opportunities and concerns regarding their integration into practice. Smartphone apps relating to major vascular diseases were identified from the app stores for the 6 most popular smartphone platforms, including iPhone, Android, Blackberry, Nokia, Windows, and Samsung. Search terms included peripheral artery (arterial) disease, varicose veins, aortic aneurysm, carotid artery disease, amputation, ulcers, hyperhydrosis, thoracic outlet syndrome, vascular malformation, and lymphatic disorders. Forty-nine vascular-themed apps were identified. Sixteen (33%) were free of charge. Fifteen apps (31%) had customer satisfaction ratings, but only 3 (6%) had greater than 100. Only 13 apps (27%) had documented medical professional involvement in their design or content. The integration of apps into the delivery of care has the potential to benefit vascular health care workers and patients. However, high-quality apps designed by clinicians with vascular expertise are currently lacking and represent an area of concern in the mHealth market. Improvement in the quality and reliability of these apps will require the development of robust regulation. Copyright © 2013 Elsevier Inc. All rights reserved.

Linacs for medical and industrial applications

International Nuclear Information System (INIS)

Hamm, R.W.

1986-01-01

Linear accelerators for medical and industrial applications have become an important commercial business. Microwave electron linacs for cancer radiation therapy and high-energy industrial radiography form the bulk of this market, but these, as well as induction linacs, are now being offered for radiation processing applications such as sterilization of disposable medical products, food preservation and material modifications. The radio frequency quadrupole (RFQ) linac has now made the ion linac also practical for commercial applications in medicine and industry, including radiation therapy, isotope production, neutron production, materials modification, and energy transfer processes. Ion linacs for several of these applications will soon be commercially available. The market for both ion and electron linacs is expected to significantly grow in several exciting and important areas

Medical and biomedical applications of shock waves

CERN Document Server

Loske, Achim M

2017-01-01

This book provides current, comprehensive, and clear explanations of the physics behind medical and biomedical applications of shock waves. Extracorporeal shock wave lithotripsy is one of the greatest medical advances of our time, and its techniques and clinical devices are continuously evolving. Further research continues to improve the understanding of calculi fragmentation and tissue-damaging mechanisms. Shock waves are also used in orthopedics and traumatology. Possible applications in oncology, cardiology, dentistry, gene therapy, cell transfection, transformation of fungi and bacteria, as well as the inactivation of microorganisms are promising approaches for clinical treatment, industrial applications and research. Medical and Biomedical Applications of Shock Waves is useful as a guide for students, technicians and researchers working in universities and laboratories. Chemists, biologists, physicians and veterinarians, involved in research or clinical practice will find useful advice, but also engineer...

Ionizing radiations: medical and industrial applications

International Nuclear Information System (INIS)

Vidal, H.

1994-01-01

Medical diagnosis with X-rays is the best known use of ionizing radiations on account of its wide diffusion (about 57 500 units in France). Other medical applications of artificial radionuclides involving a smaller number of installations are also well known, i.e. gamma teletherapy (167 units), brachytherapy (119 units) or therapy using unsealed sources (257 units). The industrial uses of ionising radiation, the diversity of which is very large, are generally less well known. The use of X- and gamma rays for non-destructive testing or food preservation and the use of tracers have some notoriety, but few people know that radioactive sources are involved in the measurement of parameters controlling industrial processes. The number of persons authorized to hold, use and/or sell artificial radionuclides amounts to about 4 800, all applications included. Approximately 650 of them are involved in therapy and 500 in medical research. The aim of this paper, which is not exhaustive, is to review a few typical applications of radionuclides both in the medical and industrial fields. It also supplies data both on the number of people authorized to use each technique and the radionuclides involved. (author). 10 tabs

The regulation of mobile medical applications.

Science.gov (United States)

Yetisen, Ali Kemal; Martinez-Hurtado, J L; da Cruz Vasconcellos, Fernando; Simsekler, M C Emre; Akram, Muhammad Safwan; Lowe, Christopher R

2014-03-07

The rapidly expanding number of mobile medical applications have the potential to transform the patient-healthcare provider relationship by improving the turnaround time and reducing costs. In September 2013, the U.S. Food and Drug Administration (FDA) issued guidance to regulate these applications and protect consumers by minimising the risks associated with their unintended use. This guidance distinguishes between the subset of mobile medical apps which may be subject to regulation and those that are not. The marketing claims of the application determine the intent. Areas of concern include compliance with regular updates of the operating systems and of the mobile medical apps themselves. In this article, we explain the essence of this FDA guidance by providing examples and evaluating the impact on academia, industry and other key stakeholders, such as patients and clinicians. Our assessment indicates that awareness and incorporation of the guidelines into product development can hasten the commercialisation and market entry process. Furthermore, potential obstacles have been discussed and directions for future development suggested.

Medical applications of colloids

CERN Document Server

Matijevic, Egon

2008-01-01

The first book of its type on the medical and biomedical applications of colloids, although there are some related titles on different topicsDiscusses the effects of uniform particles in drug formulations and releaseEvaluates particle transport and deposition in the human body.

42 CFR 436.840 - Medically needy resource standard: General requirements.

Science.gov (United States)

2010-10-01

... THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource Standard... eligibility under the cash assistance programs that are related to the State's covered medically needy group or groups of individuals under § 436.301. (b) The resource standard established under paragraph (a...

[VR and AR Applications in Medical Practice and Education].

Science.gov (United States)

Hsieh, Min-Chai; Lin, Yu-Hsuan

2017-12-01

As technology advances, mobile devices have gradually turned into wearable devices. Furthermore, virtual reality (VR), augmented reality (AR), and mixed reality (MR) are being increasingly applied in medical fields such as medical education and training, surgical simulation, neurological rehabilitation, psychotherapy, and telemedicine. Research results demonstrate the ability of VR, AR, and MR to ameliorate the inconveniences that are often associated with traditional medical care, reduce incidents of medical malpractice caused by unskilled operations, and reduce the cost of medical education and training. What is more, the application of these technologies has enhanced the effectiveness of medical education and training, raised the level of diagnosis and treatment, improved the doctor-patient relationship, and boosted the efficiency of medical execution. The present study introduces VR, AR, and MR applications in medical practice and education with the aim of helping health professionals better understand the applications and use these technologies to improve the quality of medical care.

Laser Isotope Enrichment for Medical and Industrial Applications

Energy Technology Data Exchange (ETDEWEB)

Leonard Bond

2006-07-01

Laser Isotope Enrichment for Medical and Industrial Applications by Jeff Eerkens (University of Missouri), Jay Kunze (Idaho State University), and Leonard Bond (Idaho National Laboratory) The principal isotope enrichment business in the world is the enrichment of uranium for commercial power reactor fuels. However, there are a number of other needs for separated isotopes. Some examples are: 1) Pure isotopic targets for irradiation to produce medical radioisotopes. 2) Pure isotopes for semiconductors. 3) Low neutron capture isotopes for various uses in nuclear reactors. 4) Isotopes for industrial tracer/identification applications. Examples of interest to medicine are targets to produce radio-isotopes such as S-33, Mo-98, Mo-100, W-186, Sn-112; while for MRI diagnostics, the non-radioactive Xe-129 isotope is wanted. For super-semiconductor applications some desired industrial isotopes are Si-28, Ga-69, Ge-74, Se-80, Te-128, etc. An example of a low cross section isotope for use in reactors is Zn-68 as a corrosion inhibitor material in nuclear reactor primary systems. Neutron activation of Ar isotopes is of interest in industrial tracer and diagnostic applications (e.g. oil-logging). . In the past few years there has been a sufficient supply of isotopes in common demand, because of huge Russian stockpiles produced with old electromagnetic and centrifuge separators previously used for uranium enrichment. Production of specialized isotopes in the USA has been largely accomplished using old ”calutrons” (electromagnetic separators) at Oak Ridge National Laboratory. These methods of separating isotopes are rather energy inefficient. Use of lasers for isotope separation has been considered for many decades. None of the proposed methods have attained sufficient proof of principal status to be economically attractive to pursue commercially. Some of the authors have succeeded in separating sulfur isotopes using a rather new and different method, known as condensation

Laser Isotope Enrichment for Medical and Industrial Applications

International Nuclear Information System (INIS)

Leonard Bond

2006-01-01

Laser Isotope Enrichment for Medical and Industrial Applications by Jeff Eerkens (University of Missouri), Jay Kunze (Idaho State University), and Leonard Bond (Idaho National Laboratory) The principal isotope enrichment business in the world is the enrichment of uranium for commercial power reactor fuels. However, there are a number of other needs for separated isotopes. Some examples are: (1) Pure isotopic targets for irradiation to produce medical radioisotopes. (2) Pure isotopes for semiconductors. (3) Low neutron capture isotopes for various uses in nuclear reactors. (4) Isotopes for industrial tracer/identification applications. Examples of interest to medicine are targets to produce radio-isotopes such as S-33, Mo-98, Mo-100, W-186, Sn-112; while for MRI diagnostics, the non-radioactive Xe-129 isotope is wanted. For super-semiconductor applications some desired industrial isotopes are Si-28, Ga-69, Ge-74, Se-80, Te-128, etc. An example of a low cross section isotope for use in reactors is Zn-68 as a corrosion inhibitor material in nuclear reactor primary systems. Neutron activation of Ar isotopes is of interest in industrial tracer and diagnostic applications (e.g. oil-logging). . In the past few years there has been a sufficient supply of isotopes in common demand, because of huge Russian stockpiles produced with old electromagnetic and centrifuge separators previously used for uranium enrichment. Production of specialized isotopes in the USA has been largely accomplished using old ''calutrons'' (electromagnetic separators) at Oak Ridge National Laboratory. These methods of separating isotopes are rather energy inefficient. Use of lasers for isotope separation has been considered for many decades. None of the proposed methods have attained sufficient proof of principal status to be economically attractive to pursue commercially. Some of the authors have succeeded in separating sulfur isotopes using a rather new and different method, known as condensation

Calibration services for medical applications of radiation

Energy Technology Data Exchange (ETDEWEB)

DeWerd, L.A.

1993-12-31

Calibration services for the medical community applications of radiation involve measuring radiation precisely and having traceability to the National Institute of Standards and Technology (NIST). Radiation therapy applications involve the use of ionization chambers and electrometers for external beams and well-type ionization chamber systems as well as radioactive sources for brachytherapy. Diagnostic x-ray applications involve ionization chamber systems and devices to measure other parameters of the x-ray machine, such as non-invasive kVp meters. Calibration laboratories have been established to provide radiation calibration services while maintaining traceability to NIST. New radiation applications of the medical community spur investigation to provide the future calibration needs.

Calibration services for medical applications of radiation

International Nuclear Information System (INIS)

DeWerd, L.A.

1993-01-01

Calibration services for the medical community applications of radiation involve measuring radiation precisely and having traceability to the National Institute of Standards and Technology (NIST). Radiation therapy applications involve the use of ionization chambers and electrometers for external beams and well-type ionization chamber systems as well as radioactive sources for brachytherapy. Diagnostic x-ray applications involve ionization chamber systems and devices to measure other parameters of the x-ray machine, such as non-invasive kVp meters. Calibration laboratories have been established to provide radiation calibration services while maintaining traceability to NIST. New radiation applications of the medical community spur investigation to provide the future calibration needs

Differential barometric-based positioning technique for indoor elevation measurement in IoT medical applications.

Science.gov (United States)

Wang, Hua; Wen, Yingyou; Zhao, Dazhe

2017-07-20

Medical applications have begun to benefit from Internet of Things (IoT) technology through the introduction of wearable devices. Several medical applications require accurate patient location as various changes affect pressure parameters inside the body. This study aims to develop a system to measure indoor altitude for IoT medical applications. We propose a differential barometric-based positioning system to estimate the altitude between a reference sensor and a localizing sensor connected to the human body. The differential barometric altimetry model is introduced to estimate indoor elevations and eliminate environmental artifacts. In addition, a Gaussian filter processing is adopted to remove noise from the elevation measurements. The proposed system is then investigated through extensive experiments, using various evaluation criteria. The results indicate that the proposed system yielded good accuracy with reduced implementation complexity and fewer costs. The proposed system is resilient compared to other indoor localization approaches, even when numerous environmental artifacts in indoor environments are present.

Regulation E 69-14. Monitoring requirements for medical devices

International Nuclear Information System (INIS)

2015-01-01

In the 'Regulations for the State Evaluation and Registration of Medical Equipment' force (Hereinafter Rules) set forth in Chapter VII, Articles 79 and 86, the monitoring activity as one of the programs necessary for evaluating the safety and effectiveness of medical monitoring equipment. In the years 2008 and 2011 were approved and implemented by the Center for State Control of Medical Equipment (CCEEM) Regulations and -1.1 ER and ER-1 that support and regulatory requirements 'Control and monitoring of pacemakers and implantable defibrillators' and 'Assessment, recording and control after market surgical silicone implants,' which are specific to these products and have provided a useful result for the performance of the activity. Given the number and diversity of high-risk medical devices as implantable or sustain human life that are brought into our National Health System (SNS), a regulation establishing control over the behavior becomes necessary safety and effectiveness of this equipment during use, which provide inputs to risk management. The objective of this regulation is to establish the regulatory requirements for tracking medical equipment introduced in the NHS. The provisions of this Regulation is aimed at health institutions, to CECMED as manufacturers, suppliers, distributors and importers of medical equipment.

Understanding the health care utilization of children who require medical technology: A descriptive study of children who require tracheostomies.

Science.gov (United States)

Spratling, Regena

2017-04-01

Children who require medical technology have complex chronic illnesses. This medical technology, including ventilators, oximeters, tracheostomy tubes, and feeding tubes, allows children and their families to live at home; however, the management of the children's care by informal caregivers is complex with the need for intensive, specialized care. The purpose of this study was to examine the sociodemographic and clinical characteristics that affect health care utilization in a population of children who require medical technology. A retrospective electronic health record (EHR) review was completed on the EHR records on 171 children who require medical technology, specifically tracheostomies, at an outpatient technology dependent pulmonary clinic over a three year period (January 2010-December 2012). Descriptive statistics were used to analyze sociodemographic and clinical characteristics, including medical diagnoses, and emergency department (ED) visits and hospitalizations. Of the 171 children requiring medical technology studied, there were numerous medical diagnoses (n=791), 99% had chronic illnesses affecting two or more body systems, and 88% required two or more technologies, including a tracheostomy and a feeding tube. In addition, 91% of the children had at least one ED visit or hospitalization and were treated in the ED approximately three times over the three year period. The findings from this study noted an increased utilization of health care by these children, and identified common symptoms and medical technologies for which caregivers may need interventions, focusing on education in managing symptoms and medical technology prior to presentation to the ED or hospital. Copyright © 2017 Elsevier Inc. All rights reserved.

Present and perspective medical applications of microbial exopolysaccharides

Directory of Open Access Journals (Sweden)

Misu - Moscovici

2015-09-01

Full Text Available Microbial exopolysaccharides (EPS have found outstanding medical applications since the mid-twentieth century, with the first clinical trials on dextran solutions as plasma expanders. Other EPS entered medicine firstly as conventional pharmaceutical excipients (e.g., xanthan - as suspension stabilizer, or pullulan – in capsules and oral care products. Polysaccharides, initially obtained from plant or animal sources, became easily available for a wide range of applications, especially when they were commercially produced by microbial fermentation. Alginates are used as anti-reflux, dental impressions, or as matrix for tablets. Hyaluronic acid and derivatives are used in surgery, arthritis treatment or wound healing. Bacterial cellulose is applied in wound dressings or scaffolds for tissue engineering. The development of drug controlled-release systems and of micro- and nanoparticulated ones, has opened a new era of medical applications for biopolymers. EPS and their derivatives are well suited potentially non-toxic, biodegradable drug carriers. Such systems concern rating and targeting of controlled release. Their large area of applications is explained by the available manifold series of derivatives, whose useful properties can be thereby controlled. From matrix inclusion to conjugates, different systems have been designed to solubilize, and to assure stable transport in the body, target accumulation and variable rate-release of a drug substance. From controlled drug delivery, EPS potential applications expanded to vaccine adjuvants and diagnostic imaging systems. Other potential applications are related to the bioactive (immunomodulator, antitumor, antiviral characteristics of EPS. The numerous potential applications still wait to be developed into commercial pharmaceuticals and medical devices. Based on previous and recent results in important medical-pharmaceutical domains, one can undoubtedly state that EPS medical applications have a

Microfluidics for medical applications

NARCIS (Netherlands)

van den Berg, Albert; van den Berg, A.; Segerink, L.I.; Segerink, Loes Irene; Unknown, [Unknown

2015-01-01

Lab-on-a-chip devices for point of care diagnostics have been present in clinics for several years now. Alongside their continual development, research is underway to bring the organs and tissue on-a-chip to the patient, amongst other medical applications of microfluidics. This book provides the

21 CFR 515.11 - Supplemental medicated feed mill license applications.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Supplemental medicated feed mill license... SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Applications § 515.11 Supplemental medicated feed mill license applications. (a) After approval of a medicated feed...

Calibration and application of medical particle accelerators to space radiation experiments

International Nuclear Information System (INIS)

Ryu, Kwangsun; Park, Miyoung; Chae, Jangsoo; Yoon, Sangpil; Shin, Dongho

2012-01-01

In this paper, we introduce radioisotope facilities and medical particle accelerators that can be applied to space radiation experiments and the experimental conditions required by the space radiation experiments. Space radiation experiments on the ground are critical in determining the lifetimes of satellites and in choosing or preparing the appropriate electrical parts to assure the designated mission lifetime. Before the completion of building the 100-MeV proton linear accelerator in Gyeongju, or even after the completion, the currently existing proton accelerators for medical purposes could suggest an alternative plan. We have performed experiments to calibrate medical proton beam accelerators to investigate whether the beam conditions are suitable for applications to space radiation experiments. Based on the calibration results, we propose reference beam operation conditions for space radiation experiments.

High-quality laser-accelerated ion beams for medical applications

Energy Technology Data Exchange (ETDEWEB)

Harman, Zoltan; Keitel, Christoph H. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Salamin, Yousef I. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); American University of Sharjah (United Arab Emirates)

2009-07-01

Cancer radiation therapy requires accelerated ion beams of high energy sharpness and a narrow spatial profile. As shown recently, linearly and radially polarized, tightly focused and thus extremely strong laser beams should permit the direct acceleration of light atomic nuclei up to energies that may offer the potentiality for medical applications. Radially polarized beams have better emittance than their linearly polarized counterparts. We put forward the direct laser acceleration of ions, once the refocusing of ion beams by external fields is solved or radially polarized laser pulses of sufficient power can be generated.

Mammalian synthetic biology: emerging medical applications.

Science.gov (United States)

Kis, Zoltán; Pereira, Hugo Sant'Ana; Homma, Takayuki; Pedrigi, Ryan M; Krams, Rob

2015-05-06

In this review, we discuss new emerging medical applications of the rapidly evolving field of mammalian synthetic biology. We start with simple mammalian synthetic biological components and move towards more complex and therapy-oriented gene circuits. A comprehensive list of ON-OFF switches, categorized into transcriptional, post-transcriptional, translational and post-translational, is presented in the first sections. Subsequently, Boolean logic gates, synthetic mammalian oscillators and toggle switches will be described. Several synthetic gene networks are further reviewed in the medical applications section, including cancer therapy gene circuits, immuno-regulatory networks, among others. The final sections focus on the applicability of synthetic gene networks to drug discovery, drug delivery, receptor-activating gene circuits and mammalian biomanufacturing processes. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Frontier of Advanced Accelerator Applications and Medical Treatments Using Nuclear Techniques. Abstract

International Nuclear Information System (INIS)

2015-01-01

To address the challenges of research-based practice, developing advanced accelerator applications, and medical treatments using nuclear tecniqoes, researchers from Rajamakala University of Technology Lanna, Office of Atoms for Peace, and Chiang Mai University have joined in hosting this conference. Nuclear medicine, amedical specialty, diagnoses and treats diseases in a safe and painless way. Nuclear techniques can determine medical information that may otherwise be unavailable, require surgery, or necessitate more expensive and invasive diagnostic tests. Advance in nuclear techniques also offer the potential to detect abnormalities at earlier stages, leasding to earlier treatment and a more successful prognosis.

``Low Power Wireless Technologies: An Approach to Medical Applications''

Science.gov (United States)

Bellido O., Francisco J.; González R., Miguel; Moreno M., Antonio; de La Cruz F, José Luis

Wireless communication supposed a great both -quantitative and qualitative, jump in the management of the information, allowing the access and interchange of it without the need of a physical cable connection. The wireless transmission of voice and information has remained in constant evolution, arising new standards like BluetoothTM, WibreeTM or ZigbeeTM developed under the IEEE 802.15 norm. These newest wireless technologies are oriented to systems of communication of short-medium distance and optimized for a low cost and minor consume, becoming recognized as a flexible and reliable medium for data communications across a broad range of applications due to the potential that the wireless networks presents to operate in demanding environments providing clear advantages in cost, size, power, flexibility, and distributed intelligence. About the medical applications, the remote health or telecare (also called eHealth) is getting a bigger place into the manufacturers and medical companies, in order to incorporate products for assisted living and remote monitoring of health parameteres. At this point, the IEEE 1073, Personal Health Devices Working Group, stablish the framework for these kind of applications. Particularly, the 1073.3.X describes the physical and transport layers, where the new ultra low power short range wireless technologies can play a big role, providing solutions that allow the design of products which are particularly appropriate for monitor people’s health with interoperability requirements.

Digitization of medical documents: an X-Windows application for fast scanning.

Science.gov (United States)

Muñoz, A; Salvador, C H; Gonzalez, M A; Dueñas, A

1992-01-01

This paper deals with digitization, using a commercial scanner, of medical documents as still images for introduction into a computer-based Information System. Document management involves storing, editing and transmission. This task has usually been approached from the perspective of the difficulties posed by radiologic images because of their indisputable qualitative and quantitative significance. However, healthcare activities require the management of many other types of documents and involve the requirements of numerous users. One key to document management will be the availability of a digitizer to deal with the greatest possible number of different types of documents. This paper describes the relevant aspects of documents and the technical specifications that digitizers must fulfill. The concept of document type is introduced as the ideal set of digitizing parameters for a given document. The use of document type parameters can drastically reduce the time the user spends in scanning sessions. Presentation is made of an application based on Unix, X-Windows and OSF/Motif, with a GPIB interface, implemented around the document type concept. Finally, the results of the evaluation of the application are presented, focusing on the user interface, as well as on the viewing of color images in an X-Windows environment and the use of lossy algorithms in the compression of medical images.

24 CFR 266.105 - Application requirements.

Science.gov (United States)

2010-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Housing Finance Agency Requirements § 266.105 Application requirements. (a) Applications for approval as a HUD...

78 FR 29390 - Applications; SHINE Medical Technologies, Inc.

Science.gov (United States)

2013-05-20

... NUCLEAR REGULATORY COMMISSION [Proj-0792; NRC-2013-0053] Applications; SHINE Medical Technologies... (ADAMS) Accession No. ML13088A192), SHINE Medical Technologies (SHINE) filed with the U.S. Nuclear... for a medical radioisotope production facility in Janesville, Wisconsin. An exemption from certain...

Early phase telemedicine requirements elicitation in collaboration with medical practitioners

NARCIS (Netherlands)

Larburu Rubio, Nekane; Widya, I.A.; Bults, Richard G.A.; Hermens, Hermanus J.; Napolitano, Carlo

2013-01-01

Ubiquity of Information and Communication Technology enables innovative telemedicine treatment applications for disease management of ambulant patients. Development of new treatment applications must comply with medical protocols and ‘way of working’ to obtain safety and efficacy evidence before

Measuring emotional intelligence of medical school applicants.

Science.gov (United States)

Carrothers, R M; Gregory, S W; Gallagher, T J

2000-05-01

To discuss the development, pilot testing, and analysis of a 34-item semantic differential instrument for measuring medical school applicants' emotional intelligence (the EI instrument). The authors analyzed data from the admission interviews of 147 1997 applicants to a six-year BS/MD program that is composed of three consortium universities. They compared the applicants' scores on traditional admission criteria (e.g., GPA and traditional interview assessments) with their scores on the EI instrument (which comprised five dimensions of emotional intelligence), breaking the data out by consortium university (each of which has its own educational ethos) and gender. They assessed the EI instrument's reliability and validity for assessing noncognitive personal and interpersonal qualities of medical school applicants. The five dimensions of emotional intelligence (maturity, compassion, morality, sociability, and calm disposition) indicated fair to excellent internal consistency: reliability coefficients were .66 to .95. Emotional intelligence as measured by the instrument was related to both being female and matriculating at the consortium university that has an educational ethos that values the social sciences and humanities. Based on this pilot study, the 34-item EI instrument demonstrates the ability to measure attributes that indicate desirable personal and interpersonal skills in medical school applicants.

Medical exposures requirements, present situation and prospects

International Nuclear Information System (INIS)

Cardenas Herrera, Juan

2012-01-01

Scope of medical exposures is studied, these include: exposure to patients as part of their diagnosis or treatment, exposures to persons who knowingly have assisted patients, exposures volunteers included in biomedical research programs. Medical exposures have contributed their benefits for human health improvement: possess a necessary character that people have to be exposed to radiation doses to achieve their goals, convergence of risk and benefit in the same individual is presented, variability is implicated in dose given to patients in terms of size and distribution, have contributed significantly to the doses received by the world population. Despite the above attributes and generally contribute to the direct benefit of the patient, long has been given less attention than other forms of exposure, there still potential for dose reduction to patients as a result of the applications of ionizing radiation. Currently have used for nuclear medicine diagnostic x-ray procedures, exams MN, radiotherapy, tomography, both medical and dental radiology. (author) [es

Optical Fibre Pressure Sensors in Medical Applications

Directory of Open Access Journals (Sweden)

Sven Poeggel

2015-07-01

Full Text Available This article is focused on reviewing the current state-of-the-art of optical fibre pressure sensors for medical applications. Optical fibres have inherent advantages due to their small size, immunity to electromagnetic interferences and their suitability for remote monitoring and multiplexing. The small dimensions of optical fibre-based pressure sensors, together with being lightweight and flexible, mean that they are minimally invasive for many medical applications and, thus, particularly suited to in vivo measurement. This means that the sensor can be placed directly inside a patient, e.g., for urodynamic and cardiovascular assessment. This paper presents an overview of the recent developments in optical fibre-based pressure measurements with particular reference to these application areas.

Optical Fibre Pressure Sensors in Medical Applications.

Science.gov (United States)

Poeggel, Sven; Tosi, Daniele; Duraibabu, DineshBabu; Leen, Gabriel; McGrath, Deirdre; Lewis, Elfed

2015-07-15

This article is focused on reviewing the current state-of-the-art of optical fibre pressure sensors for medical applications. Optical fibres have inherent advantages due to their small size, immunity to electromagnetic interferences and their suitability for remote monitoring and multiplexing. The small dimensions of optical fibre-based pressure sensors, together with being lightweight and flexible, mean that they are minimally invasive for many medical applications and, thus, particularly suited to in vivo measurement. This means that the sensor can be placed directly inside a patient, e.g., for urodynamic and cardiovascular assessment. This paper presents an overview of the recent developments in optical fibre-based pressure measurements with particular reference to these application areas.

Optical Fibre Pressure Sensors in Medical Applications

Science.gov (United States)

Poeggel, Sven; Tosi, Daniele; Duraibabu, DineshBabu; Leen, Gabriel; McGrath, Deirdre; Lewis, Elfed

2015-01-01

This article is focused on reviewing the current state-of-the-art of optical fibre pressure sensors for medical applications. Optical fibres have inherent advantages due to their small size, immunity to electromagnetic interferences and their suitability for remote monitoring and multiplexing. The small dimensions of optical fibre-based pressure sensors, together with being lightweight and flexible, mean that they are minimally invasive for many medical applications and, thus, particularly suited to in vivo measurement. This means that the sensor can be placed directly inside a patient, e.g., for urodynamic and cardiovascular assessment. This paper presents an overview of the recent developments in optical fibre-based pressure measurements with particular reference to these application areas. PMID:26184228

Biomagnetics and bioimaging for medical applications

Energy Technology Data Exchange (ETDEWEB)

Ueno, Shoogo [Department of Biomedical Engineering, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)]. E-mail: ueno@medes.m.u-tokyo.ac.jp; Sekino, Masaki [Department of Biomedical Engineering, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

2006-09-15

This paper reviews medical applications of the recently developed techniques in biomagnetics and bioimaging such as transcranial magnetic stimulation, magnetoencephalography, magnetic resonance imaging, cancer therapy based on magnetic stimulation, and magnetic control of cell orientation and cell growth. These techniques are leading medicine and biology into a new horizon through the novel applications of magnetism.

Biomagnetics and bioimaging for medical applications

International Nuclear Information System (INIS)

Ueno, Shoogo; Sekino, Masaki

2006-01-01

This paper reviews medical applications of the recently developed techniques in biomagnetics and bioimaging such as transcranial magnetic stimulation, magnetoencephalography, magnetic resonance imaging, cancer therapy based on magnetic stimulation, and magnetic control of cell orientation and cell growth. These techniques are leading medicine and biology into a new horizon through the novel applications of magnetism

Applications of VLSI circuits to medical imaging

International Nuclear Information System (INIS)

O'Donnell, M.

1988-01-01

In this paper the application of advanced VLSI circuits to medical imaging is explored. The relationship of both general purpose signal processing chips and custom devices to medical imaging is discussed using examples of fabricated chips. In addition, advanced CAD tools for silicon compilation are presented. Devices built with these tools represent a possible alternative to custom devices and general purpose signal processors for the next generation of medical imaging systems

Polyetheretherketone (PEEK) for medical applications.

Science.gov (United States)

Panayotov, Ivan Vladislavov; Orti, Valérie; Cuisinier, Frédéric; Yachouh, Jacques

2016-07-01

Polyetheretherketone (PEEK) is a polyaromatic semi-crystalline thermoplastic polymer with mechanical properties favorable for bio-medical applications. Polyetheretherketone forms: PEEK-LT1, PEEK-LT2, and PEEK-LT3 have already been applied in different surgical fields: spine surgery, orthopedic surgery, maxillo-facial surgery etc. Synthesis of PEEK composites broadens the physicochemical and mechanical properties of PEEK materials. To improve their osteoinductive and antimicrobial capabilities, different types of functionalization of PEEK surfaces and changes in PEEK structure were proposed. PEEK based materials are becoming an important group of biomaterials used for bone and cartilage replacement as well as in a large number of diverse medical fields. The current paper describes the structural changes and the surface functionalization of PEEK materials and their most common biomedical applications. The possibility to use these materials in 3D printing process could increase the scientific interest and their future development as well.

Medical Applications of Laser Induced Breakdown Spectroscopy

International Nuclear Information System (INIS)

Pathak, A K; Rai, N K; Singh, Ankita; Rai, A K; Rai, Pradeep K; Rai, Pramod K

2014-01-01

Sedentary lifestyle of human beings has resulted in various diseases and in turn we require a potential tool that can be used to address various issues related to human health. Laser Induced Breakdown Spectroscopy (LIBS) is one such potential optical analytical tool that has become quite popular because of its distinctive features that include applicability to any type/phase of samples with almost no sample preparation. Several reports are available that discusses the capabilities of LIBS, suitable for various applications in different branches of science which cannot be addressed by traditional analytical methods but only few reports are available for the medical applications of LIBS. In the present work, LIBS has been implemented to understand the role of various elements in the formation of gallstones (formed under the empyema and mucocele state of gallbladder) samples along with patient history that were collected from Purvancal region of Uttar Pradesh, India. The occurrence statistics of gallstones under the present study reveal higher occurrence of gallstones in female patients. The gallstone occurrence was found more prevalent for those male patients who were having the habit of either tobacco chewing, smoking or drinking alcohols. This work further reports in-situ LIBS study of deciduous tooth and in-vivo LIBS study of human nail

Viewpoints on Medical Image Processing: From Science to Application

Science.gov (United States)

Deserno (né Lehmann), Thomas M.; Handels, Heinz; Maier-Hein (né Fritzsche), Klaus H.; Mersmann, Sven; Palm, Christoph; Tolxdorff, Thomas; Wagenknecht, Gudrun; Wittenberg, Thomas

2013-01-01

Medical image processing provides core innovation for medical imaging. This paper is focused on recent developments from science to applications analyzing the past fifteen years of history of the proceedings of the German annual meeting on medical image processing (BVM). Furthermore, some members of the program committee present their personal points of views: (i) multi-modality for imaging and diagnosis, (ii) analysis of diffusion-weighted imaging, (iii) model-based image analysis, (iv) registration of section images, (v) from images to information in digital endoscopy, and (vi) virtual reality and robotics. Medical imaging and medical image computing is seen as field of rapid development with clear trends to integrated applications in diagnostics, treatment planning and treatment. PMID:24078804

Viewpoints on Medical Image Processing: From Science to Application.

Science.gov (United States)

Deserno Né Lehmann, Thomas M; Handels, Heinz; Maier-Hein Né Fritzsche, Klaus H; Mersmann, Sven; Palm, Christoph; Tolxdorff, Thomas; Wagenknecht, Gudrun; Wittenberg, Thomas

2013-05-01

Medical image processing provides core innovation for medical imaging. This paper is focused on recent developments from science to applications analyzing the past fifteen years of history of the proceedings of the German annual meeting on medical image processing (BVM). Furthermore, some members of the program committee present their personal points of views: (i) multi-modality for imaging and diagnosis, (ii) analysis of diffusion-weighted imaging, (iii) model-based image analysis, (iv) registration of section images, (v) from images to information in digital endoscopy, and (vi) virtual reality and robotics. Medical imaging and medical image computing is seen as field of rapid development with clear trends to integrated applications in diagnostics, treatment planning and treatment.

Medical image informatics infrastructure design and applications.

Science.gov (United States)

Huang, H K; Wong, S T; Pietka, E

1997-01-01

Picture archiving and communication systems (PACS) is a system integration of multimodality images and health information systems designed for improving the operation of a radiology department. As it evolves, PACS becomes a hospital image document management system with a voluminous image and related data file repository. A medical image informatics infrastructure can be designed to take advantage of existing data, providing PACS with add-on value for health care service, research, and education. A medical image informatics infrastructure (MIII) consists of the following components: medical images and associated data (including PACS database), image processing, data/knowledge base management, visualization, graphic user interface, communication networking, and application oriented software. This paper describes these components and their logical connection, and illustrates some applications based on the concept of the MIII.

Applications of Particle Accelerators in Medical Physics

OpenAIRE

Cuttone, G

2008-01-01

Particle accelerators are often associated to high energy or nuclear physics. As well pointed out in literature [1] if we kindly analyse the number of installation worldwide we can easily note that about 50% is mainly devoted to medical applications (radiotherapy, medical radioisotopes production, biomedical research). Particle accelerators are also playing an important indirect role considering the improvement of the technical features of medical diagnostic. In fact the use of radionuclide f...

Applications of artificial neural networks in medical science.

Science.gov (United States)

Patel, Jigneshkumar L; Goyal, Ramesh K

2007-09-01

Computer technology has been advanced tremendously and the interest has been increased for the potential use of 'Artificial Intelligence (AI)' in medicine and biological research. One of the most interesting and extensively studied branches of AI is the 'Artificial Neural Networks (ANNs)'. Basically, ANNs are the mathematical algorithms, generated by computers. ANNs learn from standard data and capture the knowledge contained in the data. Trained ANNs approach the functionality of small biological neural cluster in a very fundamental manner. They are the digitized model of biological brain and can detect complex nonlinear relationships between dependent as well as independent variables in a data where human brain may fail to detect. Nowadays, ANNs are widely used for medical applications in various disciplines of medicine especially in cardiology. ANNs have been extensively applied in diagnosis, electronic signal analysis, medical image analysis and radiology. ANNs have been used by many authors for modeling in medicine and clinical research. Applications of ANNs are increasing in pharmacoepidemiology and medical data mining. In this paper, authors have summarized various applications of ANNs in medical science.

76 FR 10908 - Draft Guidance for Industry on Medication Guides-Distribution Requirements and Inclusion of...

Science.gov (United States)

2011-02-28

...] Draft Guidance for Industry on Medication Guides--Distribution Requirements and Inclusion of Medication... a draft guidance for industry entitled ``Medication Guides--Distribution Requirements and Inclusion... Inclusion of Medication Guides in Risk Evaluation and Mitigation Strategies (REMS).'' This draft guidance is...

Medical and surgical applications of space biosensor technology

Science.gov (United States)

Hines, J. W.

1996-01-01

Researchers in space life sciences are rapidly approaching a technology impasse. Many of the critical questions on the impact of spaceflight on living systems simply cannot be answered with the limited available technologies. Research subjects, particularly small animal models like the rat, must be allowed to function relatively untended and unrestrained for long periods to fully reflect the impact of microgravity and spaceflight on their behavior and physiology. These requirements preclude the use of present hard-wired instrumentation techniques and limited data acquisition systems. Implantable sensors and miniaturized biotelemetry are the only means of capturing the fundamental and critical data. This same biosensor and biotelemetry technology has direct application to Earth-based medicine and surgery. Continuous, on-line data acquisition and improved measurement capabilities combined with the ease and flexibility offered by automated, wireless, and portable instruments and data systems, should provide a boon to the health care industry. Playing a key role in this technology revolution is the Sensors 2000! (S2K!) Program at NASA Ames Research Center. S2K!, in collaboration with space life sciences researchers and managers, provides an integrated capability for sensor technology development and applications, including advanced biosensor technology development, spaceflight hardware development, and technology transfer and commercialization. S2K! is presently collaborating on several spaceflight projects with dual-use medical applications. One prime example is a collaboration with the Fetal Treatment Center (FTC) at the University of California at San Francisco. The goal is to develop and apply implantable chemical sensor and biotelemetry technology to continuously monitor fetal patients during extra-uterine surgery, replacement into the womb, through birth and beyond. Once validated for ground use, the method will be transitioned to spaceflight applications to

Medical and surgical applications of space biosensor technology

Science.gov (United States)

Hines, John W.

1996-02-01

Researchers in space life sciences are rapidly approaching a technology impasse. Many of the critical questions on the impact of spaceflight on living systems simply cannot be answered with the limited available technologies. Research subjects, particularly small animal models like the rat, must be allowed to function relatively untended and unrestrained for long periods to fully reflect the impact of microgravity and spaceflight on their behavior and physiology. These requirements preclude the use of present hard-wired instrumentation techniques and limited data acquisition systems. Implantable sensors and miniaturized biotelemetry are the only means of capturing the fundamental and critical data. This same biosensor and biotelemetry technology has direct application to Earth-based medicine and surgery. Continuous, on-line data acquisition and improved measurement capabilities combined with the ease and flexibility offered by automated, wireless, and portable instruments and data systems, should provide a boon to the health care industry. Playing a key role in this technology revolution is the Sensors 2000! (S2K!) Program at NASA Ames Research Center. S2K!, in collaboration with space life sciences researchers and managers, provides an integrated capability for sensor technology development and applications, including advanced biosensor technology development, spaceflight hardware development, and technology transfer and commercialization. S2K! is presently collaborating on several spaceflight projects with dual-use medical applications. One prime example is a collaboration with the Fetal Treatment Center (FTC) at the University of California at San Francisco. The goal is to develop and apply implantable chemical sensor and biotelemetry technology to continuously monitor fetal patients during extra-uterine surgery, replacement into the womb, through birth and beyond. Once validated for ground use, the method will be transitioned to spaceflight applications to

An Overview of Recent Application of Medical Infrared Thermography in Sports Medicine in Austria

Directory of Open Access Journals (Sweden)

Carolin Hildebrandt

2010-05-01

Full Text Available Medical infrared thermography (MIT is used for analyzing physiological functions related to skin temperature. Technological advances have made MIT a reliable medical measurement tool. This paper provides an overview of MIT´s technical requirements and usefulness in sports medicine, with a special focus on overuse and traumatic knee injuries. Case studies are used to illustrate the clinical applicability and limitations of MIT. It is concluded that MIT is a non-invasive, non-radiating, low cost detection tool which should be applied for pre-scanning athletes in sports medicine.

Medical applications for biomaterials in Bolivia

CERN Document Server

Arias, Susan

2015-01-01

This book investigates the potential medical benefits natural biomaterials can offer in developing countries by analyzing the case of Bolivia. The book explores the medical and health related applications of Bolivian commodities: quinoa, barley, sugarcane, corn, sorghum and sunflower seeds. This book helps readers better understand some of the key health concerns facing countries like Bolivia and how naturally derived biomaterials and therapeutics could help substantially alleviate many of their problems.

The medically examined applicant for private insurance and his/her right to informed consent: a comparative analysis.

Science.gov (United States)

Defloor, Sarah

2011-05-01

Within the context of health and insurance law, an important question that arises is "to what extent is an applicant for private insurance truly capable of giving his/her 'free' and informed consent for a medical examination?". It should be borne in mind that it is the private insurer who requires a medical examination in order to gather medical information, and, moreover, that the insurer will not be inclined to conclude or carry out an insurance contract without this medical information. A distinction has to be made between not being free by legal coercion and not being (completely) free by factual circumstances. Exercising the right to informed consent involves exactly weighing up the consequences of the decision. Hence the applicant must be put in a position of being able to weigh up the consequences and take them into consideration.

22 CFR 42.66 - Medical examination.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Medical examination. 42.66 Section 42.66... NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

Medication-use evaluation with a Web application.

Science.gov (United States)

Burk, Muriel; Moore, Von; Glassman, Peter; Good, Chester B; Emmendorfer, Thomas; Leadholm, Thomas C; Cunningham, Francesca

2013-12-15

A Web-based application for coordinating medication-use evaluation (MUE) initiatives within the Veterans Affairs (VA) health care system is described. The MUE Tracker (MUET) software program was created to improve VA's ability to conduct national medication-related interventions throughout its network of 147 medical centers. MUET initiatives are centrally coordinated by the VA Center for Medication Safety (VAMedSAFE), which monitors the agency's integrated databases for indications of suboptimal prescribing or drug therapy monitoring and adverse treatment outcomes. When a pharmacovigilance signal is detected, VAMedSAFE identifies "trigger groups" of at-risk veterans and uploads patient lists to the secure MUET application, where locally designated personnel (typically pharmacists) can access and use the data to target risk-reduction efforts. Local data on patient-specific interventions are stored in a centralized database and regularly updated to enable tracking and reporting for surveillance and quality-improvement purposes; aggregated data can be further analyzed for provider education and benchmarking. In a three-year pilot project, the MUET program was found effective in promoting improved prescribing of erythropoiesis-stimulating agents (ESAs) and enhanced laboratory monitoring of ESA-treated patients in all specified trigger groups. The MUET initiative has since been expanded to target other high-risk drugs, and efforts are underway to refine the tool for broader utility. The MUET application has enabled the increased standardization of medication safety initiatives across the VA system and may serve as a useful model for the development of pharmacovigilance tools by other large integrated health care systems.

Medical Application of Free Electron Laser Trasmittance using Hollow Optical Fiber

CERN Document Server

Suzuki, Sachiko; Ishii, Katsonuri

2004-01-01

Mid-infrared Free Electron Laser (FEL) is expected as new application for biomedical surgery. However, delivery of MIR-FEL into the body is difficult because the common glass optical fibers have strong absorption at MIR region. A good operational and flexible line for FEL is required at medical field. A Hollow optical fiber is developed for IR laser and high-power laser delivery. We evaluated the fiber for FEL transmission line. This fiber is coated with cyclic olefin polymer (COP) and silver thin film on the inside of glass capillary tube. It is 700 μm-bore and 1m in lengths. The fiber transmission loss of the measured wavelength region of 5.5 μm to 12 μm is less than 1dB/m when the fiber is straight and 1.2 dB/m when bent to radius of 20 cm. Additionally, the output beam profile and the pulse structure is not so different form incidence beam. In conclusion, the fiber is suitable for delivery of the FEL energy for applications in medical and laser surgery.

46 CFR 10.215 - Medical and physical requirements.

Science.gov (United States)

2010-10-01

... be able to grasp, lift, and manipulate various common shipboard tools; move hands and arms to open... an applicant's ability to hear may impact maritime safety, the examining medical practitioner, if not... safety or if table 10.215(a) shows that the mariner must pass a demonstration of physical ability, but he...

User experience integrated life-style cloud-based medical application.

Science.gov (United States)

Serban, Alexandru; Lupşe, Oana Sorina; Stoicu-Tivadar, Lăcrămioara

2015-01-01

Having a modern application capable to automatically collect and process data from users, based on information and lifestyle answers is one of current challenges for researchers and medical science. The purpose of the current study is to integrate user experience design (UXD) in a cloud-based medical application to improve patient safety, quality of care and organizational efficiency. The process consists of collecting traditional and new data from patients and users using online questionnaires. A questionnaire dynamically asks questions about the user's current diet and lifestyle. After the user will introduce the data, the application will formulate a presumptive nutritional plan and will suggest different medical recommendations regarding a healthy lifestyle, and calculates a risk factor for diseases. This software application, by design and usability will be an efficient tool dedicated for fitness, nutrition and health professionals.

Medical applications of diamond particles & surfaces

OpenAIRE

Roger J Narayan; Ryan D. Boehm; Anirudha V. Sumant

2011-01-01

Diamond has been considered for use in several medical applications due to its unique mechanical, chemical, optical, and biological properties. In this paper, methods for preparing synthetic diamond surfaces and particles are described. In addition, recent developments involving the use of diamond in prostheses, sensing, imaging, and drug delivery applications are reviewed. These developments suggest that diamond-containing structures will provide significant improvements in the diagnosis and...

Nano materials for Medical and Dental Applications

International Nuclear Information System (INIS)

Yub Kwon, T.; Oh, D.S.; Narayanan, R.

2015-01-01

Welcome to this special issue. Nano science and nano technology concepts are applicable across all fields of science and a more widespread application of nano materials and nano technologies is imminent or already occurring in many areas, including health care. Today is scientists take those cutting-edge technologies and concepts and apply them to medicine and dentistry. They are finding a wide variety of ways to make medical and dental materials at the nano scale to take advantage of their enhanced physical and biological properties.The purpose of this special issue is to publish high-quality research papers as well as review articles addressing recent advances in the field of nano materials for medical and dental applications. A particular interest is given to papers exploring or discussing nano materials and nano technologies related to delivery system, bonding substitutes, and surface modification techniques applicable in these areas. For this special issue, several investigators were invited to contribute original research findings that can stimulate continuing efforts to understand the cutting-edge applications of nano materials in medicine and dentistry.

A special designed library for medical imaging applications

International Nuclear Information System (INIS)

Lymberopoulos, D.; Kotsopoulos, S.; Zoupas, V.; Yoldassis, N.; Spyropoulos, C.

1994-01-01

The present paper deals with a sophisticated and flexible library of medical purpose image processing routines. It contains modules for simple as well as advanced gray or colour image processing. This library offers powerful features for medical image processing and analysis applications, thus providing the physician with a means of analyzing and estimating medical images in order to accomplish their diagnostic procedures

Nuclear data for medical applications

International Nuclear Information System (INIS)

Capote, Roberto

2011-01-01

Nuclear science plays an increasingly important role in medical applications, in particular the need for radioisotopes in both cancer therapy and diagnostic techniques is very well established. Over the previous thirty years, many laboratories have reported a significant body of experimental data relevant to medical radionuclide production, and international data centres have compiled most of these data. However, till late 90s no systematic effort had been devoted to their standardization and assembly. These needs are being addressed through three IAEA Coordinated Research Projects on Nuclear Data for the Production of Radionuclides that started in 1999. Monitor cross sections to be used in charged particle measurements have been also evaluated (see http://www-nds.iaea.org/medical/monitor reactions.html). A review of IAEA recommended cross sections for the production of medical radioisotopes will be presented. Theoretical modelling of nuclear reactions will be discussed both for nuclear data evaluation and validation. The role of the Recommended Input Parameter Library (RIPL) in defining the input for production codes like EMPIRE and TALYS will be highlighted. (author)

15 CFR Notes Applicable to State... - Notes applicable to State of Understanding related to Medical Equipment:

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Notes applicable to State of Understanding related to Medical Equipment: applicable Notes applicable to State of Understanding related to Medical Equipment: Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY,...

Medical applications of multi-wire proportional chambers

International Nuclear Information System (INIS)

Reading, D.H.

1976-05-01

The adaption of Multi-Wire Proportional Chambers (MWPC) for medical applications has necessitated bi-dimensional readout. This is achieved by analysing signals induced onto the cathode planes. At a useful X-ray energy of 40 to 45 keV, just above the K absorption edge in Xenon, the efficiency and resolution are both optimized. Poor resolution events due to K shell fluorescent capture and Auger emission, or L shell photo-electron emission, may be rejected by using energy discrimination - resulting in approximately halving the efficiency to 8% for a 1.6 cm thick atmospheric pressure chamber, but with sub millimeter inherent resolution. This is still far inferior to film resolution, but the MWPC is useful when numbers are required for computation or retrieval. Short descriptions of the MWPC applications to bone density measurements and tomography are given. Its use when pressurized as a gamma camera is discussed, and it is concluded that it may prove useful as a portable special purpose camera, or as one with a very large area thus compensating for low efficiency. Developments with liquid filled chambers are given and also the promising positron imaging hybrid MWPC. (author)

Admission Control Over Internet of Vehicles Attached With Medical Sensors for Ubiquitous Healthcare Applications.

Science.gov (United States)

Lin, Di; Labeau, Fabrice; Yao, Yuanzhe; Vasilakos, Athanasios V; Tang, Yu

2016-07-01

Wireless technologies and vehicle-mounted or wearable medical sensors are pervasive to support ubiquitous healthcare applications. However, a critical issue of using wireless communications under a healthcare scenario rests at the electromagnetic interference (EMI) caused by radio frequency transmission. A high level of EMI may lead to a critical malfunction of medical sensors, and in such a scenario, a few users who are not transmitting emergency data could be required to reduce their transmit power or even temporarily disconnect from the network in order to guarantee the normal operation of medical sensors as well as the transmission of emergency data. In this paper, we propose a joint power and admission control algorithm to schedule the users' transmission of medical data. The objective of this algorithm is to minimize the number of users who are forced to disconnect from the network while keeping the EMI on medical sensors at an acceptable level. We show that a fixed point of proposed algorithm always exists, and at the fixed point, our proposed algorithm can minimize the number of low-priority users who are required to disconnect from the network. Numerical results illustrate that the proposed algorithm can achieve robust performance against the variations of mobile hospital environments.

[Standards in Medical Informatics: Fundamentals and Applications].

Science.gov (United States)

Suárez-Obando, Fernando; Camacho Sánchez, Jhon

2013-09-01

The use of computers in medical practice has enabled novel forms of communication to be developed in health care. The optimization of communication processes is achieved through the use of standards to harmonize the exchange of information and provide a common language for all those involved. This article describes the concept of a standard applied to medical informatics and its importance in the development of various applications, such as computational representation of medical knowledge, disease classification and coding systems, medical literature searches and integration of biological and clinical sciences. Copyright © 2013 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

A special designed library for medical imaging applications

Energy Technology Data Exchange (ETDEWEB)

Lymberopoulos, D; Kotsopoulos, S; Zoupas, V; Yoldassis, N [Departmeent of Electrical Engineering, University of Patras, Patras 26 110 Greece (Greece); Spyropoulos, C [School of Medicine, Regional University Hospital, University of Patras, Patras 26 110 Greece (Greece)

1994-12-31

The present paper deals with a sophisticated and flexible library of medical purpose image processing routines. It contains modules for simple as well as advanced gray or colour image processing. This library offers powerful features for medical image processing and analysis applications, thus providing the physician with a means of analyzing and estimating medical images in order to accomplish their diagnostic procedures. 6 refs, 1 figs.

Machine learning for epigenetics and future medical applications.

Science.gov (United States)

Holder, Lawrence B; Haque, M Muksitul; Skinner, Michael K

2017-07-03

Understanding epigenetic processes holds immense promise for medical applications. Advances in Machine Learning (ML) are critical to realize this promise. Previous studies used epigenetic data sets associated with the germline transmission of epigenetic transgenerational inheritance of disease and novel ML approaches to predict genome-wide locations of critical epimutations. A combination of Active Learning (ACL) and Imbalanced Class Learning (ICL) was used to address past problems with ML to develop a more efficient feature selection process and address the imbalance problem in all genomic data sets. The power of this novel ML approach and our ability to predict epigenetic phenomena and associated disease is suggested. The current approach requires extensive computation of features over the genome. A promising new approach is to introduce Deep Learning (DL) for the generation and simultaneous computation of novel genomic features tuned to the classification task. This approach can be used with any genomic or biological data set applied to medicine. The application of molecular epigenetic data in advanced machine learning analysis to medicine is the focus of this review.

Integrated medication management in mHealth applications.

Science.gov (United States)

Ebner, Hubert; Modre-Osprian, Robert; Kastner, Peter; Schreier, Günter

2014-01-01

Continuous medication monitoring is essential for successful management of heart failure patients. Experiences with the recently established heart failure network HerzMobil Tirol show that medication monitoring limited to heart failure specific drugs could be insufficient, in particular for general practitioners. Additionally, some patients are confused about monitoring only part of their prescribed drugs. Sometimes medication will be changed without informing the responsible physician. As part of the upcoming Austrian electronic health record system ELGA, the eMedication system will collect prescription and dispensing data of drugs and these data will be accessible to authorized healthcare professionals on an inter-institutional level. Therefore, we propose two concepts on integrated medication management in mHealth applications that integrate ELGA eMedication and closed-loop mHealth-based telemonitoring. As a next step, we will implement these concepts and analyze--in a feasibility study--usability and practicability as well as legal aspects with respect to automatic data transfer from the ELGA eMedication service.

Application of the medical data warehousing architecture EPIDWARE to epidemiological follow-up: data extraction and transformation.

Science.gov (United States)

Kerkri, E; Quantin, C; Yetongnon, K; Allaert, F A; Dusserre, L

1999-01-01

In this paper, we present an application of EPIDWARE, medical data warehousing architecture, to our epidemiological follow-up project. The aim of this project is to extract and regroup information from various information systems for epidemiological studies. We give a description of the requirements of the epidemiological follow-up project such as anonymity of medical data information and data file linkage procedure. We introduce the concept of Data Warehousing Architecture. The particularities of data extraction and transformation are presented and discussed.

30 CFR 7.83 - Application requirements.

Science.gov (United States)

2010-07-01

...) Injector nozzle; (9) Injection fuel pump; (10) Governor; (11) Turbocharger, if applicable; (12) Aftercooler... APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Diesel Engines Intended for Use in Underground Coal Mines § 7.83 Application requirements. (a) An application for approval of a diesel engine...

Medical applications of model-based dynamic thermography

Science.gov (United States)

Nowakowski, Antoni; Kaczmarek, Mariusz; Ruminski, Jacek; Hryciuk, Marcin; Renkielska, Alicja; Grudzinski, Jacek; Siebert, Janusz; Jagielak, Dariusz; Rogowski, Jan; Roszak, Krzysztof; Stojek, Wojciech

2001-03-01

The proposal to use active thermography in medical diagnostics is promising in some applications concerning investigation of directly accessible parts of the human body. The combination of dynamic thermograms with thermal models of investigated structures gives attractive possibility to make internal structure reconstruction basing on different thermal properties of biological tissues. Measurements of temperature distribution synchronized with external light excitation allow registration of dynamic changes of local temperature dependent on heat exchange conditions. Preliminary results of active thermography applications in medicine are discussed. For skin and under- skin tissues an equivalent thermal model may be determined. For the assumed model its effective parameters may be reconstructed basing on the results of transient thermal processes. For known thermal diffusivity and conductivity of specific tissues the local thickness of a two or three layer structure may be calculated. Results of some medical cases as well as reference data of in vivo study on animals are presented. The method was also applied to evaluate the state of the human heart during the open chest cardio-surgical interventions. Reference studies of evoked heart infarct in pigs are referred, too. We see the proposed new in medical applications technique as a promising diagnostic tool. It is a fully non-invasive, clean, handy, fast and affordable method giving not only qualitative view of investigated surfaces but also an objective quantitative measurement result, accurate enough for many applications including fast screening of affected tissues.

78 FR 12329 - Distinguishing Medical Device Recalls From Product Enhancements; Reporting Requirements; Draft...

Science.gov (United States)

2013-02-22

... medical devices to take timely action to correct violative devices or remove them from the marketplace...] Distinguishing Medical Device Recalls From Product Enhancements; Reporting Requirements; Draft Guidance for... draft guidance entitled ``Distinguishing Medical Device Recalls From Product Enhancements; Reporting...

Functionalized Nanodiamonds for Biological and Medical Applications.

Science.gov (United States)

Lai, Lin; Barnard, Amanda S

2015-02-01

Nanodiamond is a promising material for biological and medical applications, owning to its relatively inexpensive and large-scale synthesis, unique structure, and superior optical properties. However, most biomedical applications, such as drug delivery and bio-imaging, are dependent upon the precise control of the surfaces, and can be significantly affected by the type, distribution and stability of chemical funtionalisations of the nanodiamond surface. In this paper, recent studies on nanodiamonds and their biomedical applications by conjugating with different chemicals are reviewed, while highlighting the critical importance of surface chemical states for various applications.

Multilevel Modeling and Policy Development: Guidelines and Applications to Medical Travel

Science.gov (United States)

Garcia-Garzon, Eduardo; Zhukovsky, Peter; Haller, Elisa; Plakolm, Sara; Fink, David; Petrova, Dafina; Mahalingam, Vaishali; Menezes, Igor G.; Ruggeri, Kai

2016-01-01

Medical travel has expanded rapidly in recent years, resulting in new markets and increased access to medical care. Whereas several studies investigated the motives of individuals seeking healthcare abroad, the conventional analytical approach is limited by substantial caveats. Classical techniques as found in the literature cannot provide sufficient insight due to the nested nature of data generated. The application of adequate analytical techniques, specifically multilevel modeling, is scarce to non-existent in the context of medical travel. This study introduces the guidelines for application of multilevel techniques in public health research by presenting an application of multilevel modeling in analyzing the decision-making patterns of potential medical travelers. Benefits and potential limitations are discussed. PMID:27252672

Multilevel Modeling and Policy Development: Guidelines and Applications to Medical Travel.

Science.gov (United States)

Garcia-Garzon, Eduardo; Zhukovsky, Peter; Haller, Elisa; Plakolm, Sara; Fink, David; Petrova, Dafina; Mahalingam, Vaishali; Menezes, Igor G; Ruggeri, Kai

2016-01-01

Medical travel has expanded rapidly in recent years, resulting in new markets and increased access to medical care. Whereas several studies investigated the motives of individuals seeking healthcare abroad, the conventional analytical approach is limited by substantial caveats. Classical techniques as found in the literature cannot provide sufficient insight due to the nested nature of data generated. The application of adequate analytical techniques, specifically multilevel modeling, is scarce to non-existent in the context of medical travel. This study introduces the guidelines for application of multilevel techniques in public health research by presenting an application of multilevel modeling in analyzing the decision-making patterns of potential medical travelers. Benefits and potential limitations are discussed.

Radiation protection in medical research. Licensing requirement for the use of radiation and advice for the application procedure; Strahlenschutz in der medizinischen Forschung. Genehmigungsbeduerftigkeit von Strahlenanwendungen und Hinweise zum Antragsverfahren

Energy Technology Data Exchange (ETDEWEB)

Minkov, V.; Klammer, H.; Brix, G. [Bundesamt fuer Strahlenschutz, Abteilung fuer medizinischen und beruflichen Strahlenschutz, Neuherberg (Germany)

2017-07-15

In Germany, persons who are to be exposed to radiation for medical research purposes are protected by a licensing requirement. However, there are considerable uncertainties on the part of the applicants as to whether licensing by the competent Federal Office for Radiation Protection is necessary, and regarding the choice of application procedure. The article provides explanatory notes and practical assistance for applicants and an outlook on the forthcoming new regulations concerning the law on radiation protection of persons in the field of medical research. Questions and typical mistakes in the application process were identified and evaluated. The qualified physicians involved in a study are responsible for deciding whether a license is required for the intended application of radiation. The decision can be guided by answering the key question whether the study participants would undergo the same exposures regarding type and extent if they had not taken part in the study. When physicians are still unsure about their decision, they can seek the advisory service provided by the professional medical societies. Certain groups of people are particularly protected through the prohibition or restriction of radiation exposure. A simplified licensing procedure is used for a proportion of diagnostic procedures involving radiation when all related requirements are met; otherwise, the regular licensing procedure should be used. The new radiation protection law, which will enter into force on the 31st of december 2018, provides a notification procedure in addition to deadlines for both the notification and the licensing procedures. In the article, the authors consider how eligible studies involving applications of radiation that are legally not admissible at present may be feasible in the future, while still ensuring a high protection level for study participants. (orig.) [German] Personen, bei denen Strahlenanwendungen zum Zweck der medizinischen Forschung durchgefuehrt

E-SAP: efficient-strong authentication protocol for healthcare applications using wireless medical sensor networks.

Science.gov (United States)

Kumar, Pardeep; Lee, Sang-Gon; Lee, Hoon-Jae

2012-01-01

A wireless medical sensor network (WMSN) can sense humans' physiological signs without sacrificing patient comfort and transmit patient vital signs to health professionals' hand-held devices. The patient physiological data are highly sensitive and WMSNs are extremely vulnerable to many attacks. Therefore, it must be ensured that patients' medical signs are not exposed to unauthorized users. Consequently, strong user authentication is the main concern for the success and large scale deployment of WMSNs. In this regard, this paper presents an efficient, strong authentication protocol, named E-SAP, for healthcare application using WMSNs. The proposed E-SAP includes: (1) a two-factor (i.e., password and smartcard) professional authentication; (2) mutual authentication between the professional and the medical sensor; (3) symmetric encryption/decryption for providing message confidentiality; (4) establishment of a secure session key at the end of authentication; and (5) professionals can change their password. Further, the proposed protocol requires three message exchanges between the professional, medical sensor node and gateway node, and achieves efficiency (i.e., low computation and communication cost). Through the formal analysis, security analysis and performance analysis, we demonstrate that E-SAP is more secure against many practical attacks, and allows a tradeoff between the security and the performance cost for healthcare application using WMSNs.

E-SAP: Efficient-Strong Authentication Protocol for Healthcare Applications Using Wireless Medical Sensor Networks

Directory of Open Access Journals (Sweden)

Hoon-Jae Lee

2012-02-01

Full Text Available A wireless medical sensor network (WMSN can sense humans’ physiological signs without sacrificing patient comfort and transmit patient vital signs to health professionals’ hand-held devices. The patient physiological data are highly sensitive and WMSNs are extremely vulnerable to many attacks. Therefore, it must be ensured that patients’ medical signs are not exposed to unauthorized users. Consequently, strong user authentication is the main concern for the success and large scale deployment of WMSNs. In this regard, this paper presents an efficient, strong authentication protocol, named E-SAP, for healthcare application using WMSNs. The proposed E-SAP includes: (1 a two-factor (i.e., password and smartcard professional authentication; (2 mutual authentication between the professional and the medical sensor; (3 symmetric encryption/decryption for providing message confidentiality; (4 establishment of a secure session key at the end of authentication; and (5 professionals can change their password. Further, the proposed protocol requires three message exchanges between the professional, medical sensor node and gateway node, and achieves efficiency (i.e., low computation and communication cost. Through the formal analysis, security analysis and performance analysis, we demonstrate that E-SAP is more secure against many practical attacks, and allows a tradeoff between the security and the performance cost for healthcare application using WMSNs.

Nuclear data for medical applications: an overview

International Nuclear Information System (INIS)

Qaim, S.M.

2001-01-01

A brief introduction to nuclear data in medicine is given. The choice of a radioisotope for medical application demands an accurate knowledge of radioactive decay data. Short-lived single photon and β + -emitters are preferred for diagnostic investigations, and longer-lived corpuscular radiation emitting radioisotopes for endoradiotherapy. The nuclear reaction cross section data, on the other hand, are needed for optimising the production routes. Besides radioactive isotopes, the use of ionising radiation in therapy is discussed. External radiation therapy has achieved an important place in medicine. The role of nuclear data is briefly discussed; they are needed for radiation dose calculations. The hitherto rather neglected activation products in proton therapy are considered. The methodology of development of a nuclear data file for medical applications is outlined. (orig.)

Applications of medical wireless LAN systems (MedLAN)

OpenAIRE

Banitsas, KA; Istepanian, RSH; Tachakra, S

2002-01-01

This is a post-peer-review, pre-copyedit version of an article published in Journal of Medical Marketing. The definitive publisher-authenticated version "Konstantinos A. Banitsas, R.S.H. Istepanian, Sapal Tachakra. Applications of medical Wireless LAN systems (MedLAN). Journal of Medical Marketing, Volume 2, Number 2, 1 January 2002 , pp. 136-142(7)" is available online at: http://www.ingentaconnect.com/content/pal/jomm/2002/00000002/00000002/art00008. In this paper the Wireless LAN (WLAN)...

Medical Requirements During a Natural Disaster: A Case Study on WhatsApp Chats Among Medical Personnel During the 2015 Nepal Earthquake.

Science.gov (United States)

Basu, Moumita; Ghosh, Saptarshi; Jana, Arnab; Bandyopadhyay, Somprakash; Singh, Ravikant

2017-12-01

The objective of this study was to explore a log of WhatsApp messages exchanged among members of the health care group Doctors For You (DFY) while they were providing medical relief in the aftermath of the Nepal earthquake in April 2015. Our motivation was to identify medical resource requirements during a disaster in order to help government agencies and other responding organizations to be better prepared in any upcoming disaster. A large set of WhatsApp (WhatsApp Inc, Mountain View, CA) messages exchanged among DFY members during the Nepal earthquake was collected and analyzed to identify the medical resource requirements during different phases of relief operations. The study revealed detailed phase-wise requirements for various types of medical resources, including medicines, medical equipment, and medical personnel. The data also reflected some of the problems faced by the medical relief workers in the earthquake-affected region. The insights from this study may help not only the Nepalese government, but also authorities in other earthquake-prone regions of the world to better prepare for similar disasters in the future. Moreover, real-time analysis of such online data during a disaster would aid decision-makers in dynamically formulating resource-mapping strategies. (Disaster Med Public Health Preparedness. 2017;11:652-655).

Regulatory frameworks for mobile medical applications.

Science.gov (United States)

Censi, Federica; Mattei, Eugenio; Triventi, Michele; Calcagnini, Giovanni

2015-05-01

A mobile application (app) is a software program that runs on mobile communication devices such as a smartphone. The concept of a mobile medical app has gained popularity and diffusion but its reference regulatory context has raised discussion and concerns. Theoretically, a mobile app can be developed and uploaded easily by any person or entity. Thus, if an app can have some effects on the health of the users, it is mandatory to identify its reference regulatory context and the applicable prescriptions.

Preface book Microfluidics for medical applications

NARCIS (Netherlands)

van den Berg, Albert; Segerink, Loes Irene

2015-01-01

This book presents an overview of the major microfluidics techniques and platforms used for medicine and medical applications, providing the reader with an overview of the recent developments in this field. It is divided in three parts: (1) tissue and organs on-chip, (2) microfluidics for medicine

38 CFR 39.10 - Application requirements.

Science.gov (United States)

2010-07-01

...-10) Grant Requirements and Procedures § 39.10 Application requirements. (a) For a project to be..., etc., (10) Economic activities, (11) Cultural resources, (12) Aesthetics, (13) Residential population...

10 CFR 55.21 - Medical examination.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Medical examination. 55.21 Section 55.21 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) OPERATORS' LICENSES Medical Requirements § 55.21 Medical examination. An applicant for a license shall have a medical examination by a physician. A licensee shall have a medical...

40 CFR 266.80 - Applicability and requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Applicability and requirements. 266.80 Section 266.80 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... MANAGEMENT FACILITIES Spent Lead-Acid Batteries Being Reclaimed § 266.80 Applicability and requirements. (a...

Podcasting as a novel way to communicate with medical school applicants.

Science.gov (United States)

Ferguson, Benjamin D; Bister, Mary K; Krapec, Joni N

2014-09-01

Podcasting in medical education is becoming more widely used and may be a useful tool for communicating with applicants to medical school. Given recent trends in the popularity of podcasting and mobile media, we created a podcast to communicate more effectively with applicants to our medical school as well as with the broader premedical community. The purpose of this study was to characterize the listening habits and motivations of our audience and compare the podcast's benefits to those of other resources. We additionally sought to understand patterns by which our podcast was consumed by a premedical audience. We surveyed medical school applicants who interviewed at the University of Chicago Pritzker School of Medicine for matriculation in 2013. Forty-one percent of those surveyed had listened to the podcast prior to their interview. Only 12 % of listeners accessed the podcast using a mobile device. Ninety-two percent of listeners felt that it faithfully represented the medical school, and 81 % felt that listening would encourage the decision to matriculate. A majority of listeners responded that the podcast was more helpful than other traditional resources. This is the first use of podcasting in medical school admissions and represents a novel way to communicate with prospective students. Our findings demonstrate that podcasting can be an effective tool for communicating with applicants to medical school and highlight its usefulness in recruitment. This method of communication could be adopted by other medical schools to enhance the ways in which they inform their own prospective medical students.

Teleworks: a CSCW application for remote medical diagnosis support and teleconsultation.

Science.gov (United States)

Makris, L; Kamilatos, I; Kopsacheilis, E V; Strintzis, M G

1998-06-01

The present paper describes methods for the design of both synchronous and asynchronous computer-supported cooperative work (CSCW) procedures suitable for the medical application area and specifically for the purpose of medical teleconsultation and remote diagnosis support. The experimental implementation of a CSCW system built upon a PC/Windows platform is detailed as an example of a low-cost system suitable for adoption in a wide range of medical teleconsultation applications.

Medical applications of radioactive material

International Nuclear Information System (INIS)

Seidel, C.W.

1990-01-01

Hospitals, clinics and other medical complexes are probably the most extensive users of radioactive solutions of Tc-99m, Tl-201, Ga-67, I-123, Xe-133 and radiopharmaceuticals as diagnostic tools to evaluate the dynamic function of various organs in the body, detect cancerous tumors, sites of infection or other bodily dysfunctions. Examples of monitoring blood flow to a stressed heart and to the brain of a cocaine addict are shown. Short-lived positron emitting radionuclides (C-11, N-13, O-15 and F-18) are produced right in a hospital. Other radionuclides are used as therapeutics to reduce tumor size or kill diseased cells. Radioimmunoassay (RIA) is another medical diagnostic tool that is useful in the early detection of the AIDS virus and cancer as well as many other illnesses. Biological researchers, using radioactive biological compounds, have developed many of todays medical diagnostic procedures. Most of the recent Nobel Laureates in the life sciences have used radiolabeled compounds in their research. A brief review of these applications with several examples is presented

Nuclear data for medical applications: an overview

International Nuclear Information System (INIS)

Qaim, S.M.

2002-01-01

A brief introduction to nuclear data in medicine is given. The choice of a radioisotope for medical application demands an accurate knowledge of radioactive decay data. Short-lived single photon and beta sup + -emitters are preferred for diagnostic investigations, and longer-lived corpuscular radiation emitting radioisotopes for endo radiotherapy. The nuclear reaction cross section data, on the other hand, are needed for optimising the production routes. Besides radioactive isotopes, the use of ionising radiation in therapy is discussed. External radiation therapy has achieved an important place in medicine. The role of nuclear data is briefly discussed; they are needed for radiation dose calculations. The hitherto rather neglected activation products in proton therapy are considered. The methodology of development of a nuclear data file for medical applications is outlined. (author)

A survey of clinical performance skills requirements in medical radiation technology

International Nuclear Information System (INIS)

Rowntree, P.A.; Veitch, J.D.

1993-01-01

This paper outlines the reasons behind carry out a study of clinical performance skills requirements and the method being used to gather data. It describes the changes which have occurred in radiographer education in Queensland, the broader impact brought about by changes in professional body requirements and the development of a Competency based Standards Document for the profession. The paper provides examples of the survey design and layout being developed for distribution to third year students in the Medical Imaging Technology major of the Bachelor of Applied Science (Medical Radiation Technology) Queensland University of Technology, graduates and clinical departments in Queensland. 1 tab., 1 fig

14 CFR 152.113 - Application requirements: Airport planning.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Application requirements: Airport planning....113 Application requirements: Airport planning. (a) Application for Federal assistance. An eligible sponsor or planning agency that desires to obtain Federal aid for eligible airport master planning or...

From Particle Physics to Medical Applications

Science.gov (United States)

Dosanjh, Manjit

2017-06-01

CERN is the world's largest particle physics research laboratory. Since it was established in 1954, it has made an outstanding contribution to our understanding of the fundamental particles and their interactions, and also to the technologies needed to analyse their properties and behaviour. The experimental challenges have pushed the performance of particle accelerators and detectors to the limits of our technical capabilities, and these groundbreaking technologies can also have a significant impact in applications beyond particle physics. In particular, the detectors developed for particle physics have led to improved techniques for medical imaging, while accelerator technologies lie at the heart of the irradiation methods that are widely used for treating cancer. Indeed, many important diagnostic and therapeutic techniques used by healthcare professionals are based either on basic physics principles or the technologies developed to carry out physics research. Ever since the discovery of x-rays by Roentgen in 1895, physics has been instrumental in the development of technologies in the biomedical domain, including the use of ionizing radiation for medical imaging and therapy. Some key examples that are explored in detail in this book include scanners based on positron emission tomography, as well as radiation therapy for cancer treatment. Even the collaborative model of particle physics is proving to be effective in catalysing multidisciplinary research for medical applications, ensuring that pioneering physics research is exploited for the benefit of all.

Medical applications of superconducting quantum interference devices

International Nuclear Information System (INIS)

Uehara, Gen

2011-01-01

SQUIDs (Superconducting Quantum Interference Devices) are applied to clinical areas and basic medical science fields because of their potential for measuring a minute magnetic signal from the human body. Magnetoencephalography, one of their applications, is used for the functional mapping of the brain cortex before surgery and the localization of focus of epilepsy. Recently, their applications to the early-stage detection of dementia and the localization of brain ischemia are suggested. Another application of SQUIDs is magnetospinography, which detects the conduction block in spinal cord signal propagation. (author)

The revised version of the German Radiation Protection Regulatory Guide for Medical Applications (Richtlinie Strahlenschutz in der Medizin)

International Nuclear Information System (INIS)

Kemmer, W.

1995-01-01

The revised version of the regulatory guide, effective since 1 June 1993, is intended to enhance and effect in practice a harmonisation of approval and acceptance procedures and standardized testing processes for acceptance and approval, as well as to facilitate governmental supervisory functions relating to the application of radioactive substances and ionizing radiation in the medical field. The guide can furthermore serve as a useful source of reference and information for doctors or medical personnel being trained in applying the Radiation Protection Ordinance, or for acquisition of the required expert knowledge in medical radiological protection. (orig./HP) [de

Medical applications of synchrotron radiation

International Nuclear Information System (INIS)

Thomlinson, W.

1991-10-01

Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved

Medical applications of synchrotron radiation

International Nuclear Information System (INIS)

Thomlinson, W.

1992-01-01

Ever since the first diagnostic X-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become incrasingly important. Both in clinical medicine and basic research the use of X-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved. (orig.)

The medical examination in United States immigration applications: the potential use of genetic testing leads to heightened privacy concerns.

Science.gov (United States)

Burroughs, A Maxwell

2005-01-01

The medical examination has been an integral part of the immigration application process since the passing of the Immigration Act of 1891. Failing the medical examination can result in denial of the application. Over the years the medical examination has been expanded to include questioning about diseases that are scientifically shown to be rooted in an individual's genetic makeup. Recent advances in the fields of genomics and bioinformatics are making accurate and precise screening for these conditions a reality. Government policymakers will soon be faced with decisions regarding whether or not to sanction the use of these newly-developed genetic tests in the immigration application procedure. The terror threat currently facing the United States may ultimately bolster the argument in favor of genetic testing and/or DNA collection of applicants. However, the possibility of a government mandate requiring genetic testing raises a host of ethical issues; including the threat of eugenics and privacy concerns. Genetic testing has the ability to uncover a wealth of sensitive medical information about an individual and currently there are no medical information privacy protections afforded to immigration applicants. This article examines the potential for genetic testing in the immigration application process and the ethical issues surrounding this testing. In particular, this article explores the existing framework of privacy protections afforded to individuals living in the United States and how this and newly-erected standards like those released by the Health and Human Services (HHS) might apply to individuals seeking to immigrate to the United States.

Medical applications for pharmacists using mobile devices.

Science.gov (United States)

Aungst, Timothy Dy

2013-01-01

Mobile devices (eg, smartphones, tablet computers) have become ubiquitous and subsequently there has been a growth in mobile applications (apps). Concurrently, mobile devices have been integrated into health care practice due to the availability and quality of medical apps. These mobile medical apps offer increased access to clinical references and point-of-care tools. However, there has been little identification of mobile medical apps suitable for the practice of pharmacy. To address the shortage of recommendations of mobile medical apps for pharmacists in daily practice. Mobile medical apps were identified via the iTunes and Google Play Stores via the "Medical" app categories and key word searches (eg, drug information, medical calculators). In addition, reviews provided by professional mobile medical app review websites were used to identify apps. Mobile medical apps were included if they had been updated in the previous 3 months, were available in the US, used evidence-based information or literature support, had dedicated app support, and demonstrated stability. Exclusion criteria included apps that were not available in English, had advertisement bias, used nonreferenced sources, were available only via an institution-only subscription, and were web-based portals. Twenty-seven mobile apps were identified and reviewed that involved general pharmacy practice, including apps that involved drug references, clinical references, medical calculators, laboratory references, news and continuing medical education, and productivity. Mobile medical apps have a variety of features that are beneficial to pharmacy practice. Individual clinicians should consider several characteristics of these apps to determine which are suitable to incorporate into their daily practice.

An H-module linear actuator for medical equipment applications

DEFF Research Database (Denmark)

Liu, Xiao; Wu, Keyuan; ye, yunyue

2012-01-01

An H-module linear actuator (HMLA) is proposed in this paper for medical equipment applications. Compared to the existing linear actuators used in medical equipment, the proposed H-module linear actuator has much lower normal force, which makes use of an additional air-suspension system unnecessary...

Medical uses of nitinol

Energy Technology Data Exchange (ETDEWEB)

Pelton, A.R.; Stoeckel, D.; Duering, T.W. [Nitinol Devices and Components - Cordis Corp., Fremont, CA (United States)

2000-07-01

The growth of nitinol in the medical industries has exploded in the past ten years. Patients and care providers have encouraged the transition from traditional open-surgical procedures, which require long hospital stays, to less-invasive techniques, which are often performed in out-patient clinics. This demand for minimally invasive procedures has allowed novel instrumentation and implants to be designed. An increasing number of these devices use nitinol as the critical component. Examples of medical applications range from orthodontic archwires and endoscopic instruments to endovascular stents. This paper will focus on key performance attributes of nitinol that make it an ideal material for medical applications. Specific applications will be introduced through their use of the enabling features. (orig.)

47 CFR 400.4 - Application requirements.

Science.gov (United States)

2010-10-01

... Telecommunication NATIONAL TELECOMMUNICATIONS AND INFORMATION ADMINISTRATION, DEPARTMENT OF COMMERCE, AND NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION E-911 GRANT PROGRAM § 400.4 Application requirements. (a) Contents. A State's application for funds for the E-911 grant program must...

[Assessment of two applications of medication self-management in older patients. Qualitative study].

Science.gov (United States)

Carrillo, I; Guilabert, M; Pérez-Jover, V; Mira, J J

2015-01-01

The aging population and the growing use of technology are two realities of modern society. Developing tools to support medication self-management to polymedicated elderly may contribute to increase their safety. To know how patients polymedicated and older than 64 years manage dose their medication and assessment the utility of two medication self-management applications, specifically analyzing management systems, medication errors and positive and improvable aspects of each of the tools presented. Seven focal groups with 59 patients from associations and health departments were conducted. In such meetings, they received the applications and they were encouraged to use it. Then, a several group questions were asked them about their health status, how they managed their medication and their assessment about the applications. Most participants reported to use memory strategies to take correctly their medication. They assessed positively the applications although some of them showed resistance to incorporate it in their daily routine. The simple interface and ease of use were the characteristics of the applications most appreciated by patients. Is possible to foster among elderly patients the use of technological tools to support the proper administration of medications with purpose is to decrease errors and increase safety. When designing health applications is necessary to take into account the preferences of those who are targeted. Copyright © 2014 SECA. Published by Elsevier Espana. All rights reserved.

Medical application and clinical validation for reliable and trustworthy physiological monitoring using functional textiles: experience from the HeartCycle and MyHeart project.

Science.gov (United States)

Reiter, Harald; Muehlsteff, Jens; Sipilä, Auli

2011-01-01

Functional textiles are seen as promising technology to enable healthcare services and medical care outside hospitals due to their ability to integrate textile-based sensing and monitoring technologies into the daily life. In the past much effort has been spent onto basic functional textile research already showing that reliable monitoring solutions can be realized. The challenge remains to find and develop suited medical application and to fulfil the boundary conditions for medical endorsement and exploitation. The HeartCycle vest described in this abstract will serve as an example for a functional textile carefully developed according to the requirements of a specific medical application, its clinical validation, the related certification aspects and the next improvement steps towards exploitation.

EM-18-2008 regulation. Essential requirements for the registration of medical equipment

International Nuclear Information System (INIS)

2015-01-01

This rule lays down additional rules for the evaluation and the State Control of Medical Equipment provisions. Medical equipment must be designed and constructed so that they are used under the conditions and for the intended purpose and shall, where applicable, by virtue of the technical knowledge, experience, education or training of users, do not compromise the clinical condition or safety of patients, or the safety and health of users or, where applicable, other persons, assuming that any risks that may be associated with their use constitute acceptable risks versus the benefits for the patient and is compatible with a high level of protection of health and safety.

Properties and medical applications of shape memory alloys.

Science.gov (United States)

Tarniţă, Daniela; Tarniţă, D N; Bîzdoacă, N; Mîndrilă, I; Vasilescu, Mirela

2009-01-01

One of the most known intelligent material is nitinol, which offers many functional advantages over conventional implantable alloys. Applications of SMA to the biomedical field have been successful because of their functional qualities, enhancing both the possibility and the execution of less invasive surgeries. The biocompatibility of these alloys is one of their most important features. Different applications exploit the shape memory effect (one-way or two-way) and the super elasticity, so that they can be employed in orthopedic and cardiovascular applications, as well as in the manufacture of new surgical tools. Therefore, one can say that smart materials, especially SMA, are becoming noticeable in the biomedical field. Super elastic NiTi has become a material of strategic importance as it allows to overcome a wide range of technical and design issues relating to the miniaturization of medical devices and the increasing trend for less invasive and therefore less traumatic procedures. This paper will consider just why the main properties of shape memory alloys hold so many opportunities for medical devices and will review a selection of current applications.

Magnetic nanoparticle design for medical application

Czech Academy of Sciences Publication Activity Database

Mornet, S.; Vasseur, S.; Grasset, F.; Veverka, Pavel; Goglio, G.; Demourgues, A.; Portier, J.; Pollert, Emil; Duguet, E.

2006-01-01

Roč. 34, - (2006), s. 237-247 ISSN 0079-6786 R&D Projects: GA AV ČR(CZ) 1QS100100553; GA AV ČR(CZ) KAN200200651 Institutional research plan: CEZ:AV0Z10100521 Keywords : magnetic nanoparticles * medical applications * magnetic resonance imaging * magnetic hyperthermia Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.500, year: 2006

Quantitative Description of Medical Student Interest in Neurology and Psychiatry.

Science.gov (United States)

Ramos, Raddy L; Cuoco, Joshua A; Guercio, Erik; Levitan, Thomas

2016-07-01

Given the well-documented shortage of physicians in primary care and several other specialties, quantitative understanding of residency application and matching data among osteopathic and allopathic medical students has implications for predicting trends in the physician workforce. To estimate medical student interest in neurology and psychiatry based on numbers of applicants and matches to neurology and psychiatry osteopathic and allopathic residency programs. Also, to gauge students' previous academic experience with brain and cognitive sciences. The number of available postgraduate year 1 positions, applicants, and matches from graduating years 2011 through 2015 were collected from the National Matching Services Inc and the American Association of Colleges of Osteopathic Medicine for osteopathic programs and the National Resident Matching Program and the Association of American Medical Colleges for allopathic programs. To determine and compare osteopathic and allopathic medical students' interest in neurology and psychiatry, the number of positions, applicants, and matches were analyzed considering the number of total osteopathic and allopathic graduates in the given year using 2-tailed χ2 analyses with Yates correction. In addition, osteopathic and allopathic medical schools' websites were reviewed to determine whether neurology and psychiatry rotations were required. Osteopathic medical students' reported undergraduate majors were also gathered. Compared with allopathic medical students, osteopathic medical students had significantly greater interest (as measured by applicants) in neurology (χ21=11.85, Pneurology and psychiatry residency programs. Approximately 6% of osteopathic vs nearly 85% of allopathic medical schools had required neurology rotations. Nearly 10% of osteopathic applicants and matriculants had undergraduate coursework in brain and cognitive sciences. Osteopathic medical students demonstrated greater interest than allopathic medical

Medical applications of atomic force microscopy and Raman spectroscopy.

Science.gov (United States)

Choi, Samjin; Jung, Gyeong Bok; Kim, Kyung Sook; Lee, Gi-Ja; Park, Hun-Kuk

2014-01-01

This paper reviews the recent research and application of atomic force microscopy (AFM) and Raman spectroscopy techniques, which are considered the multi-functional and powerful toolkits for probing the nanostructural, biomechanical and physicochemical properties of biomedical samples in medical science. We introduce briefly the basic principles of AFM and Raman spectroscopy, followed by diagnostic assessments of some selected diseases in biomedical applications using them, including mitochondria isolated from normal and ischemic hearts, hair fibers, individual cells, and human cortical bone. Finally, AFM and Raman spectroscopy applications to investigate the effects of pharmacotherapy, surgery, and medical device therapy in various medicines from cells to soft and hard tissues are discussed, including pharmacotherapy--paclitaxel on Ishikawa and HeLa cells, telmisartan on angiotensin II, mitomycin C on strabismus surgery and eye whitening surgery, and fluoride on primary teeth--and medical device therapy--collagen cross-linking treatment for the management of progressive keratoconus, radiofrequency treatment for skin rejuvenation, physical extracorporeal shockwave therapy for healing of Achilles tendinitis, orthodontic treatment, and toothbrushing time to minimize the loss of teeth after exposure to acidic drinks.

NF EN ISO 11137-1, July 2006. Sterilization of health care products - Irradiation - Part 1: Requirements for development, validation and routine control of a sterilization process for medical devices

International Nuclear Information System (INIS)

2006-01-01

This part of the ISO 11137 standard specifies requirements for the development, validation and routine control of a radiation sterilization process for medical devices. Although the scope of this part of the ISO 11137 standard is limited to medical devices, it specifies requirements and provides guidance that may be applicable to other products and equipment. This part of the international standard covers radiation processes employing irradiators using the radionuclide 60 Co or 137 Cs, a beam from an electron generator or a beam from an X-ray generator. This part of the international standard does not: - specify requirements for development, validation and routine control of a process for inactivating the causative agents of spongiform encephalopathies such as scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease; - detail specified requirements for designating a medical device as sterile; - specify a quality management system for the control of all stages of production of medical devices; - specify requirements for occupational safety associated with the design and operation of irradiation facilities; - specify requirements for the sterilization of used or reprocessed devices

Systematic review on the effectiveness of augmented reality applications in medical training.

Science.gov (United States)

Barsom, E Z; Graafland, M; Schijven, M P

2016-10-01

Computer-based applications are increasingly used to support the training of medical professionals. Augmented reality applications (ARAs) render an interactive virtual layer on top of reality. The use of ARAs is of real interest to medical education because they blend digital elements with the physical learning environment. This will result in new educational opportunities. The aim of this systematic review is to investigate to which extent augmented reality applications are currently used to validly support medical professionals training. PubMed, Embase, INSPEC and PsychInfo were searched using predefined inclusion criteria for relevant articles up to August 2015. All study types were considered eligible. Articles concerning AR applications used to train or educate medical professionals were evaluated. Twenty-seven studies were found relevant, describing a total of seven augmented reality applications. Applications were assigned to three different categories. The first category is directed toward laparoscopic surgical training, the second category toward mixed reality training of neurosurgical procedures and the third category toward training echocardiography. Statistical pooling of data could not be performed due to heterogeneity of study designs. Face-, construct- and concurrent validity was proven for two applications directed at laparoscopic training, face- and construct validity for neurosurgical procedures and face-, content- and construct validity in echocardiography training. In the literature, none of the ARAs completed a full validation process for the purpose of use. Augmented reality applications that support blended learning in medical training have gained public and scientific interest. In order to be of value, applications must be able to transfer information to the user. Although promising, the literature to date is lacking to support such evidence.

A clinician's artificial organ? Instant messaging applications in medical care.

Science.gov (United States)

Tazegul, Gokhan; Bozoglan, Humeyra; Ogut, Tahir S; Balcı, Mustafa K

2017-09-15

After the development of the first phone at the end of 19th century, communication technologies took a great leap forward in the 20th century. With the birth of the "smartphone" in the 21st century, communication technologies exponentially evolved and became an important part of our daily routine. Effective communications between clinicians is critical in medical care and miscommunications are a source of errors. Although telecommunication technologies have proliferated dramatically in the last decade, there is scarce evidence-based information on the use of this technology in medical care. For the purposes of medical communication, we can now consult each other about patients individually and within a group via instant messaging applications by using text messages, photos, audio messages and even videos. In this review, we examine the uses and drawbacks of instant messaging applications in medical communications.

Systematic review on the effectiveness of augmented reality applications in medical training

NARCIS (Netherlands)

Barsom, E. Z.; Graafland, M.; Schijven, M. P.

2016-01-01

Computer-based applications are increasingly used to support the training of medical professionals. Augmented reality applications (ARAs) render an interactive virtual layer on top of reality. The use of ARAs is of real interest to medical education because they blend digital elements with the

Medical imaging in clinical applications algorithmic and computer-based approaches

CERN Document Server

Bhateja, Vikrant; Hassanien, Aboul

2016-01-01

This volume comprises of 21 selected chapters, including two overview chapters devoted to abdominal imaging in clinical applications supported computer aided diagnosis approaches as well as different techniques for solving the pectoral muscle extraction problem in the preprocessing part of the CAD systems for detecting breast cancer in its early stage using digital mammograms. The aim of this book is to stimulate further research in medical imaging applications based algorithmic and computer based approaches and utilize them in real-world clinical applications. The book is divided into four parts, Part-I: Clinical Applications of Medical Imaging, Part-II: Classification and clustering, Part-III: Computer Aided Diagnosis (CAD) Tools and Case Studies and Part-IV: Bio-inspiring based Computer Aided diagnosis techniques. .

[Impact of a software application to improve medication reconciliation at hospital discharge].

Science.gov (United States)

Corral Baena, S; Garabito Sánchez, M J; Ruíz Rómero, M V; Vergara Díaz, M A; Martín Chacón, E R; Fernández Moyano, A

2014-01-01

To assess the impact of a software application to improve the quality of information concerning current patient medications and changes on the discharge report after hospitalization. To analyze the incidence of errors and to classify them. Quasi-experimental pre / post study with non-equivalent control group study. Medical patients at hospital discharge. implementation of a software application. Percentage of reconciled patient medication on discharge, and percentage of patients with more than one unjustified discrepancy. A total of 349 patients were assessed; 199 (pre-intervention phase) and 150 (post-intervention phase). Before the implementation of the application in 157 patients (78.8%) medication reconciliation had been completed; finding reconciliation errors in 99 (63.0%). The most frequent type of error, 339 (78.5%), was a missing dose or administration frequency information. After implementation, all the patient prescriptions were reconciled when the software was used. The percentage of patients with unjustified discrepancies decreased from 63.0% to 11.8% with the use of the application (psoftware application has been shown to improve the quality of the information on patient treatment on the hospital discharge report, but it is still necessary to continue development as a strategy for improving medication reconciliation. Copyright © 2014 SECA. Published by Elsevier Espana. All rights reserved.

Radioprotection in the medical applications of the ionizing radiations

International Nuclear Information System (INIS)

2001-01-01

This publication presents information about of the radiological safety in the medical application of the ionizing radiation compiled in 11 chapter and 1 annex. The first four chapters are principally dedicated to technical uses in radioprotection, the external and internal irradiation and the biological radiation effects. The radioprotection principles, the individual monitoring techniques, and the radioprotection systems are developed afterwards in the followings three chapters. The second half of the document is dedicated entirely to the medical practices using ionizing radiations, specially to the radioprotection aspects in radiodiagnosis, nuclear medicine and radiotherapy. The final chapter is dedicated to radiological accidents happened worldwide in the field of the medical applications of the ionizing radiations. The annex, about of the regulatory area, established a set of standards, laws, decrees and other force regulations in radiological safety, related in radiodiagnosis, nuclear medicine and radiotherapy

Do differentials in the support and advice available at UK schools and colleges influence candidate performance in the medical school admissions interview? A survey of direct school leaver applicants to a UK medical school.

Science.gov (United States)

Lambe, Paul; Waters, Catherine; Bristow, David

2013-09-01

To our knowledge, nothing is known about whether differentials in support and advice during preparation for the interview influence candidate performance and thereby contribute to bias in selection for medical school. To assess if differences in advice and support with preparation for the medical school admissions interview given type of school last attended influence interview score achieved by direct school leaver applicants to study on an undergraduate UK medical degree course. Confidential self-completed on-line questionnaire survey. Interview performance was positively related to whether a teacher, tutor or career advisors at the School or College last attended had advised a respondent to prepare for the interview, had advised about the various styles of medical interview used and the types of questions asked, and what resources were available to help in preparation. Respondents from Private/Independent schools were more likely than those from State schools to have received such advice and support. Differentials in access to advice on and support with preparation for the medical school interview may advantage some candidates over others. This inequity would likely be ameliorated by the provision of an authoritative and comprehensive guide to applying to medical school outlining admission requirements and the preparation strategy applicants should use in order to best meet those requirements. The guide could be disseminated to the Principals of all UK schools and colleges and freely available electronic versions signposted in medical school prospectuses and the course descriptor on the Universities and Colleges Admissions Service.

Medical Applications of Remote Electronic Browsing.

Science.gov (United States)

Chadwick, Joseph

The purposes of this study are to identify and define viable remote browsing techniques and the requirements for an interactive medical information system that would permit the use of such techniques. The main emphasis is in the areas of: (1) remote viewing of page material; and (2) remote interrogation of fact banks with question-answering…

[Software as medical devices/medical apps : Tasks, requirements, and experiences from the point of view of a competent authority].

Science.gov (United States)

Terhechte, Arno

2018-03-01

Software can be classified as a medical device according to the Medical Device Directive 93/42/EEC. The number of software products and medical apps is continuously increasing and so too is the use in health institutions (e. g., in hospitals and doctors' surgeries) for diagnosis and therapy.Different aspects of standalone software and medical apps from the perspective of the authority responsible are presented. The quality system implemented to establish a risk-based systematic inspection and supervision of manufacturers is discussed. The legal framework, as well as additional standards that are the basis for inspection, are outlined. The article highlights special aspects that occur during inspection like verification of software and interfaces, and the clinical evaluation of software. The Bezirksregierung, as the local government authority responsible in North Rhine-Westphalia, is also in charge of inspection of health institutions. Therefore this article is not limited to the manufacturers placing the software on the market, but in addition it describes the management and use of software as a medical device in hospitals.The future legal framework, the Medical Device Regulation, will strengthen the requirements and engage notified bodies more than today in the conformity assessment of software as a medical device.Manufacturers, health institutions, notified bodies and the authorities responsible are in charge of intensifying their efforts towards software as a medical device. Mutual information, improvement of skills, and inspections will lead to compliance with regulatory requirements.

Requirements for Ion Sources

International Nuclear Information System (INIS)

Scrivens, R

2013-01-01

Ion sources produce beams for a large variety of different physical experiments, industrial processes and medical applications. In order to characterize the beam delivered by them, a list of requirements is necessary. In this chapter the list of principal requirements is specified and definitions for them are given. (author)

A new approach to scoring systems to improve identification of acute medical admissions that will require critical care.

Science.gov (United States)

Carmichael, H A; Robertson, E; Austin, J; McCruden, D; Messow, C M; Belcher, P R

2011-11-01

Removal of the intensive care unit (ICU) at the Vale of Leven Hospital mandated the identification and transfer out of those acute medical admissions with a high risk of requiring ICU. The aim of the study was to develop triaging tools that identified such patients and compare them with other scoring systems. The methodology included a retrospective analysis of physiological and arterial gas measurements from 1976 acute medical admissions produced PREEMPT-1 (PRE-critical Emergency Medical Patient Triage). A simpler one for ambulance use (PREAMBLE-1 [PRE-Admission Medical Blue-Light Emergency]) was produced by the addition of peripheral oxygen saturation to a modification of MEWS (Modified Early Warning Score). Prospective application of these tools produced a larger database of 4447 acute admissions from which logistic regression models produced PREEMPT-2 and PREAMBLE-2, which were then compared with the original systems and seven other early warning scoring systems. Results showed that in patients with arterial gases, the area under the receiver operator characteristic curve was significantly higher in PREEMPT-2 (89·1%) and PREAMBLE-2 (84.4%) than all other scoring systems. Similarly, in all patients, it was higher in PREAMBLE-2 (92·4%) than PREAMBLE-1 (88·1%) and the other scoring systems. In conclusion, risk of requiring ICU can be more accurately predicted using PREEMPT-2 and PREAMBLE-2, as described here, than by other early warning scoring systems developed over recent years.

A clean bill of health for CERN’s medical applications office

CERN Multimedia

2014-01-01

Many of you will have had the opportunity to follow the seminar on medical applications given by two members of our new International Strategy Committee for medical applications on 20 November. This occasion gives me a good opportunity to take stock of what’s been achieved since we set up our office for medical applications under Steve Myers almost a year ago.   It’s already an impressive list of achievements, and one that’s poised to grow. The International Strategy Committee is perhaps the most visible part of it. Meeting for the first time last week, the Committee will help us focus and prioritise our efforts so we can extract the maximum benefit. The existence of the office itself is already a major step in this direction: today, instead of having seven separate medical initiatives at CERN, we have a single coordinated approach and each component benefits. Let’s take a look at the current state of progress. The study to develop LEIR into the OPENM...

Development of a high resolution voxelised head phantom for medical physics applications.

Science.gov (United States)

Giacometti, V; Guatelli, S; Bazalova-Carter, M; Rosenfeld, A B; Schulte, R W

2017-01-01

Computational anthropomorphic phantoms have become an important investigation tool for medical imaging and dosimetry for radiotherapy and radiation protection. The development of computational phantoms with realistic anatomical features contribute significantly to the development of novel methods in medical physics. For many applications, it is desirable that such computational phantoms have a real-world physical counterpart in order to verify the obtained results. In this work, we report the development of a voxelised phantom, the HIGH_RES_HEAD, modelling a paediatric head based on the commercial phantom 715-HN (CIRS). HIGH_RES_HEAD is unique for its anatomical details and high spatial resolution (0.18×0.18mm 2 pixel size). The development of such a phantom was required to investigate the performance of a new proton computed tomography (pCT) system, in terms of detector technology and image reconstruction algorithms. The HIGH_RES_HEAD was used in an ad-hoc Geant4 simulation modelling the pCT system. The simulation application was previously validated with respect to experimental results. When compared to a standard spatial resolution voxelised phantom of the same paediatric head, it was shown that in pCT reconstruction studies, the use of the HIGH_RES_HEAD translates into a reduction from 2% to 0.7% of the average relative stopping power difference between experimental and simulated results thus improving the overall quality of the head phantom simulation. The HIGH_RES_HEAD can also be used for other medical physics applications such as treatment planning studies. A second version of the voxelised phantom was created that contains a prototypic base of skull tumour and surrounding organs at risk. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Procedures for the medical application of research reactors (Appendix)

International Nuclear Information System (INIS)

Nishihara, H.; Kanda, K.

2004-01-01

The Kyoto University Reactor (KUR) is one of the four research reactors in Japan that are currently licensed for medical application, in addition to other research purposes. Taking the KUR as an example, legal and other procedures for using research reactors for boron neutron capture therapy (BNCT) are described, which are practiced in accordance with the 'Provisional Guideline Pertaining to Medical Irradiation by Accelerators and/or Reactors, other than defined by the Medical Service Act' of the Science Council of Japan

High performance graphics processors for medical imaging applications

International Nuclear Information System (INIS)

Goldwasser, S.M.; Reynolds, R.A.; Talton, D.A.; Walsh, E.S.

1989-01-01

This paper describes a family of high- performance graphics processors with special hardware for interactive visualization of 3D human anatomy. The basic architecture expands to multiple parallel processors, each processor using pipelined arithmetic and logical units for high-speed rendering of Computed Tomography (CT), Magnetic Resonance (MR) and Positron Emission Tomography (PET) data. User-selectable display alternatives include multiple 2D axial slices, reformatted images in sagittal or coronal planes and shaded 3D views. Special facilities support applications requiring color-coded display of multiple datasets (such as radiation therapy planning), or dynamic replay of time- varying volumetric data (such as cine-CT or gated MR studies of the beating heart). The current implementation is a single processor system which generates reformatted images in true real time (30 frames per second), and shaded 3D views in a few seconds per frame. It accepts full scale medical datasets in their native formats, so that minimal preprocessing delay exists between data acquisition and display

OpenICE medical device interoperability platform overview and requirement analysis.

Science.gov (United States)

Arney, David; Plourde, Jeffrey; Goldman, Julian M

2018-02-23

We give an overview of OpenICE, an open source implementation of the ASTM standard F2761 for the Integrated Clinical Environment (ICE) that leverages medical device interoperability, together with an analysis of the clinical and non-functional requirements and community process that inspired its design.

Curve Matching with Applications in Medical Imaging

DEFF Research Database (Denmark)

Bauer, Martin; Bruveris, Martins; Harms, Philipp

2015-01-01

In the recent years, Riemannian shape analysis of curves and surfaces has found several applications in medical image analysis. In this paper we present a numerical discretization of second order Sobolev metrics on the space of regular curves in Euclidean space. This class of metrics has several...

Responsibility structure in medical radiation applications

International Nuclear Information System (INIS)

Beekman, Z.M.

1989-01-01

The author discusses the various aspects of the responsibilities of physicians and clinical physicists with regard to radiation protection in medical applications of ionizing radiation. It becomes still clearer that the physician, who carries out the examination or the treatment, also has to bear the responsibility. this holds for the indication assessment as well as for optimization of the quality of the examination or treatment versus radiation burden of the patient, radiologic worker and thirds. Further it is clear that the physician in these will have to delegate specific tasks and responsibilities, whether or not in the elongated-arm construction. The clinical physicist is responsible in particular for the applications of the physical methods and watches the quality of the apparatus and methods used. As such he also is responsible for the technical workers, who take care of the preventive and corrective maintenance. The principal responsibility of the clinical physicist however lies in the field of standardization and calibration of medical-physical instruments. Besides this investigation into and development of new techniques, methods and apparatus come up, while also education and training of various profession groups involved need attention. (author). 6 refs.; 1 tab

Industrial and medical applications of accelerators with energies less than 20 MeV

International Nuclear Information System (INIS)

Duggan, J.L.

1983-01-01

In this paper the medical and industrial application of small accelerators is reviewed. Most of the material is taken from the Seventh Conference on the Application of Accelerators in Research and Industry, which was held in Denton, Texas in November of 1982. The areas covered include medical linacs, cyclotron design and production of medical radioisotopes, radiation processing, ion implantation for the metallurgical and semiconductor industries, oil and mineral exploration, trace, surface and bulk analysis, and unique accelerators for all of the above applications

The national institute of radiation hygiene and the medical application of radiation

International Nuclear Information System (INIS)

Baarli, J.

1988-01-01

This paper gives a review of the rules and regulations concerning medical application of radiation in Norway. It discusses the intention of the regulations, the way in which the regulations is applied and how the National Institute of Radiation Hygiene as the competent authority assures the application of the regulations. The paper furthermore gives an indication of the areas of radiation application in medicine and the number of location of X-ray equipment, nuclear medical laboratories, radiation therapy equipment, etc. The number of X-ray examinations in Norway per year are also given, together with their distribution among the various types of examinations. Summary results of a quality assurance investigation of nuclear medical laboratories are given, as well as the results of inspections of the various types of equipment used in medical diagnostics

Manufacturing radioactive material for medical, research and industrial applications

International Nuclear Information System (INIS)

Seidel, C.W.

1992-01-01

Hospitals, clinics and other medical complexes are among the most extensive users of radioactive material. Nuclear medicine uses radioactive solutions of Tc-99m, Tl-201, Ga-67, I-123, Xe-133 and other radiopharmaceuticals as diagnostic tools to evaluate dynamic functions of various organs in the body, detect cancerous tumors, sites of infection or other bodily dysfunctions. Examples of monitoring blood flow to the brain of a cocaine addict will be shown. Many different radionuclides are also produced for life science research and industrial applications. Some require long irradiations and are needed only periodically. Radiopharmaceutical manufactures look for reliable suppliers that can produce quality product at a reasonable cost. Worldwide production of the processed and unprocessed radionuclides and the enriched stable nuclides that are the target materials used in the accelerators and reactors around the world will be discussed. (author)

13 CFR 307.5 - Application requirements.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Application requirements. 307.5 Section 307.5 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE... EDA) a CEDS, except that a CEDS is not required when applying for a Strategy Grant; and (2) Explain...

Safety requirements applicable to the SMART design

International Nuclear Information System (INIS)

Seul, Kwang Won; Kim, Wee Kyong; Kim, Hho Jung

1999-01-01

The 330 MW thermal power of integral reactor, named SMART (System integrated Modular Advanced ReacTor), is under development at KAERI for seawater desalination application and electricity generation. The final product of nuclear desalination plant (NDP) is electricity and fresh water. Thus, in addition to the protection of the public around the plant facility from the possible release of radioactive materials, the fresh water should be prevented from radioactivity contamination. In this study, to ensure the safety of SMART reactor in the early stage of design development, the safety requirements applicable to the SMART design were investigated, based on the current regulatory requirements for the existing NPPs and the advanced light water reactor (LWR) designs. The interface requirements related to the desalination facility were also investigated, based on the recent IAEA research activities pertaining to the NDP. As a result, it was found that the current regulatory requirements and guidance for the existing NPPs and advanced LWR designs are applicable to the SMART design and its safety evaluation. However, the safety requirements related to the SMART-specific design and the desalination plant are needed to develop in the future to assure the safety of the SMART reactor

Embedded Control in Wearable Medical Devices: Application to the Artificial Pancreas

Directory of Open Access Journals (Sweden)

Stamatina Zavitsanou

2016-09-01

Full Text Available Significant increases in processing power, coupled with the miniaturization of processing units operating at low power levels, has motivated the embedding of modern control systems into medical devices. The design of such embedded decision-making strategies for medical applications is driven by multiple crucial factors, such as: (i guaranteed safety in the presence of exogenous disturbances and unexpected system failures; (ii constraints on computing resources; (iii portability and longevity in terms of size and power consumption; and (iv constraints on manufacturing and maintenance costs. Embedded control systems are especially compelling in the context of modern artificial pancreas systems (AP used in glucose regulation for patients with type 1 diabetes mellitus (T1DM. Herein, a review of potential embedded control strategies that can be leveraged in a fully-automated and portable AP is presented. Amongst competing controllers, emphasis is provided on model predictive control (MPC, since it has been established as a very promising control strategy for glucose regulation using the AP. Challenges involved in the design, implementation and validation of safety-critical embedded model predictive controllers for the AP application are discussed in detail. Additionally, the computational expenditure inherent to MPC strategies is investigated, and a comparative study of runtime performances and storage requirements among modern quadratic programming solvers is reported for a desktop environment and a prototype hardware platform.

20 CFR 416.919n - Informing the medical source of examination scheduling, report content, and signature requirements.

Science.gov (United States)

2010-04-01

... scheduling, report content, and signature requirements. 416.919n Section 416.919n Employees' Benefits SOCIAL... medical source of examination scheduling, report content, and signature requirements. The medical sources... report containing all of the elements in paragraph (c). (e) Signature requirements. All consultative...

20 CFR 404.1519n - Informing the medical source of examination scheduling, report content, and signature requirements.

Science.gov (United States)

2010-04-01

... scheduling, report content, and signature requirements. 404.1519n Section 404.1519n Employees' Benefits... medical source of examination scheduling, report content, and signature requirements. The medical sources... report containing all of the elements in paragraph (c). (e) Signature requirements. All consultative...

Applications of Novel Techniques to Health Foods, Medical and Agricultural Biotechnology

OpenAIRE

Baianu, I. C.; Lozano, P. R.; Prisecaru, V. I.; Lin, H. C.

2004-01-01

Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new niches for Biotechnology and prevent the shrinking or closing the existing ones. Amongst the selected novel techniques with applications to both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposom...

[Consideration of Mobile Medical Device Regulation].

Science.gov (United States)

Peng, Liang; Yang, Pengfei; He, Weigang

2015-07-01

The regulation of mobile medical devices is one of the hot topics in the industry now. The definition, regulation scope and requirements, potential risks of mobile medical devices were analyzed and discussed based on mobile computing techniques and the FDA guidance of mobile medical applications. The regulation work of mobile medical devices in China needs to adopt the risk-based method.

Radiation hazards from medical applications

International Nuclear Information System (INIS)

Beekman, Z.M.

1981-01-01

An introduction is presented on the radiation hazards connected with biomedical radiography and nuclear medicine. The frequency of radiodiagnostic efforts was rather high in the Netherlands. This was reduced considerably by abolishing the thorax screening of the population. About diagnostic nuclear medicine less can be said because far fewer numerical data are available. An exposition of genetically and somatically significant doses and how to compute them is given. The drawing up of a profit versus risk evaluation for medical applications of ionizing radiations is recommended. (Auth.)

Development of Standard Process for Private Information Protection of Medical Imaging Issuance

International Nuclear Information System (INIS)

Park, Bum Jin; Jeong, Jae Ho; Son, Gi Gyeong Son; Kang, Hee Doo; Yoo, Beong Gyu; Lee, Jong Seok

2009-01-01

The medical imaging issuance is changed from conventional film method to Digital Compact Disk solution because of development on IT technology. However other medical record department's are undergoing identification check through and through whereas medical imaging department cannot afford to do that. So, we examine present applicant's recognition of private intelligence safeguard, and medical imaging issuance condition by CD and DVD medium toward various medical facility and then perform comparative analysis associated with domestic and foreign law and recommendation, lastly suggest standard for medical imaging issuance and process relate with internal environment. First, we surveyed issuance process and required documents when situation of medical image issuance in the metropolitan medical facility by wire telephone between 2008.6.-12008.7.1. in accordance with the medical law Article 21clause 2, suggested standard through applicant's required documents occasionally - (1) in the event of oneself verifying identification, (2) in the event of family verifying applicant identification and family relations document (health insurance card, attested copy, and so on), (3) third person or representative verifying applicant identification and letter of attorney and certificate of one's seal impression. Second, also checked required documents of applicant in accordance with upper standard when situation of medical image issuance in Kyung-hee university medical center during 3 month 2008.5.-12008.7.31. Third, developed a work process by triangular position of issuance procedure for situation when verifying required documents and management of unpreparedness. Look all over the our manufactured output in the hospital - satisfy the all conditions 4 place(12%), possibly request everyone 4 place(12%), and apply in the clinic section 9 place(27%) that does not medical imaging issuance office, so we don't know about required documents condition. and look into whether meet or not

21 CFR 515.20 - Approval of medicated feed mill license applications.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Approval of medicated feed mill license... SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Administrative Actions on Licenses § 515.20 Approval of medicated feed mill license applications. Within 90 days after an...

Quantitative evaluation of the requirements for the promotion as associate professor at German medical faculties.

Science.gov (United States)

Sorg, Heiko; Knobloch, Karsten

2012-01-01

First quantitative evaluation of the requirements for the promotion as associate professor (AP) at German medical faculties. Analysis of the AP-regulations of German medical faculties according to a validated scoring system, which has been adapted to this study. The overall scoring for the AP-requirements at 35 German medical faculties was 13.5±0.6 of 20 possible scoring points (95% confidence interval 12.2-14.7). More than 88% of the AP-regulations demand sufficient performance in teaching and research with adequate scientific publication. Furthermore, 83% of the faculties expect an expert review of the candidate's performance. Conference presentations required as an assistant professor as well as the reduction of the minimum time as an assistant professor do only play minor roles. The requirements for assistant professors to get nominated as an associate professor at German medical faculties are high with an only small range. In detail, however, it can be seen that there still exists large heterogeneity, which hinders equal opportunities and career possibilities. These data might be used for the ongoing objective discussion.

Medical emergency aid through telematics: design, implementation guidelines and analysis of user requirements for the MERMAID project.

Science.gov (United States)

Anogianakis, G; Maglavera, S; Pomportsis, A; Bountzioukas, S; Beltrame, F; Orsi, G

1998-01-01

MERMAID is an EU financed telemedicine project with global reach and 24-h, multilingual capability. It aspires to provide a model for the provision of health care services based on the electronic transmission of medical information, via ISDN based videoconferencing. This model will not be limited to medical diagnostics but it will encompass all cases where the actual delivery of health care services involves a patient who is not located where the provider is. Its implementation requires the commissioning of an expensive telecommunications infrastructure and the exploration of a number of solutions. In fact, all categories of telemedical applications (audio and video conferencing, multimedia communications, flat file and image transfer with low, medium and high bandwidth data requirements) are considered while the full range of network choices (digital land lines, cellular/wireless, satellite and broadband) are being tested in terms of cost/performance tradeoffs that are inherent to them and the developmental stage each of these options occupies in their in its life cycle. Finally, out that MERMAID utilises advanced land based line transmission technologies to aid the remote patient by making available the specialist care that is best suited in the particular case.

75 FR 82277 - Health Insurance Issuers Implementing Medical Loss Ratio (MLR) Requirements Under the Patient...

Science.gov (United States)

2010-12-30

...-AA06 Health Insurance Issuers Implementing Medical Loss Ratio (MLR) Requirements Under the Patient... Register (FR Doc 2010-29596 (75 FR 74864)) entitled ``Health Insurance Issuers Implementing Medical Loss... request for comments entitled ``Health Insurance Issuers Implementing Medical Loss Ratio (MLR...

21 CFR 801.16 - Medical devices; Spanish-language version of certain required statements.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical devices; Spanish-language version of....16 Medical devices; Spanish-language version of certain required statements. If devices restricted to prescription use only are labeled solely in Spanish for distribution in the Commonwealth of Puerto Rico where...

Research on medical applications of radioisotopes and radiation in Australia

International Nuclear Information System (INIS)

Hardy, C.J.

1987-01-01

The Australian Atomic Energy Commission (AAEC) produces and distributes commercially in Australia and abroad a range of radioisotopes and radiopharmaceuticals for medical applications. The AAEC carries out research and development on new and improved processes and procucts is collaboration with medical specialists in hospitals and research workers in other organisations. Examples of these processes and products are: a gel generator for production of 99m Tc; radiopharmaceuticals for diagnosis of tumours and brain disease and therapy for arthritis; 64 Cu for study of copper metabolism; and monoclonal antibodies for tumour diagnosis and therapy. New medical applications in Australia of neutron irradiation include the measurement of total body nitrogen and neutron capture in boron-labelled compounds in vivo for melanoma therapy. (author)

BR2 reactor: medical and industrial applications

International Nuclear Information System (INIS)

Ponsard, B.

2005-01-01

The radioisotopes are produced for various applications in the nuclear medicine (diagnostic, therapy, palliation of metastatic bone pain), industry (radiography of welds, ...), agriculture (radiotracers, ...) and basic research. Due to the availability of high neutron fluxes (thermal neutron flux up to 10 15 n/cm 2 .s), the BR2 reactor is considered as a major facility through its contribution for a continuous supply of products such 99 Mo ( 99 mTc), 131 I, 133 Xe, 192 Ir, 186 Re, 153 Sm, 90 Y, 32 P, 188 W ( 188 Re), 203 Hg, 82 Br, 41 Ar, 125 I, 177 Lu, 89 Sr, 60 Co, 169 Yb, 147 Nd, and others. Neutron Transmutation Doped (NTD) silicon is produced for the semiconductor industry in the SIDONIE (Silicon Doping by Neutron Irradiation Experiment) facility, which is designed to continuously rotate and traverse the silicon through the neutron flux. These combined movements produce exceptional dopant homogeneity in batches of silicon measuring 4 and 5-inches in diameter by up to 750 mm in length. The main objectives of work performed were to provide a reliable and qualitative supply of radioisotopes and NTD-silicon to the customers in accordance with a quality system that has been certified to the requirements of the EN ISO 9001: 2000. This new Quality System Certificate has been obtained in November 2003 for the Production of radioisotopes for medical and industrial applications and the Production of Neutron Transmutation Doped (NTD) Silicon in the BR2 reactor

Development of scintillation materials for medical imaging and other applications

International Nuclear Information System (INIS)

Melcher, C. L.

2013-01-01

Scintillation materials that produce pulses of visible light in response to the absorption of energetic photons, neutrons, and charged particles, are widely used in various applications that require the detection of radiation. The discovery and development of new scintillators has accelerated in recent years, due in large part to their importance in medical imaging as well as in security and high energy physics applications. Better understanding of fundamental scintillation mechanisms as well as the roles played by defects and impurities have aided the development of new high performance scintillators for both gamma-ray and neutron detection. Although single crystals continue to dominate gamma-ray based imaging techniques, composite materials and transparent optical ceramics potentially offer advantages in terms of both synthesis processes and scintillation performance. A number of promising scintillator candidates have been identified during the last few years, and several are currently being actively developed for commercial production. Purification and control of raw materials and cost effective crystal growth processes can present significant challenges to the development of practical new scintillation materials.

Sovereign immunity: Principles and application in medical malpractice.

Science.gov (United States)

Suk, Michael

2012-05-01

Tort law seeks accountability when parties engage in negligent conduct, and aims to compensate the victims of such conduct. An exception to this general rule governing medical negligence is the doctrine of sovereign immunity. Historically, individuals acting under the authority of the government or other sovereign entity had almost complete protection against tort liability. This article addressed the following: (1) the development of sovereign immunity in law, (2) the lasting impact of the Federal Tort Claims Act on sovereign immunity, and (3) the contemporary application of sovereign immunity to medical malpractice, using case examples from Virginia and Florida. I performed an Internet search to identify sources that addressed the concept of sovereign immunity, followed by a focused search for relevant articles in PubMed and LexisNexis, literature databases for medical and legal professionals, respectively. Historically, sovereign liability conferred absolute immunity from lawsuits in favor of the sovereign (ie, the government). Practical considerations in our democratic system have contributed to an evolution of this doctrine. Understanding sovereign immunity and its contemporary application are of value for any physician interested in the debate concerning medical malpractice in the United States. Under certain circumstances, physicians working as employees of the federal or state government may be protected against individual liability if the government is substituted as the defendant.

Textile slow-release systems with medical applications

NARCIS (Netherlands)

ten Breteler, M.R.; Nierstrasz, Vincent; Warmoeskerken, Marinus

2002-01-01

In the development of medical drug delivery systems, attention has been increasingly focused on slow- or controlled delivery systems in order to achieve an optimal therapeutic effect. Since the administration of drugs often requires a defined or minimum effective dosage in the human body, more

User Interface Design in Medical Distributed Web Applications.

Science.gov (United States)

Serban, Alexandru; Crisan-Vida, Mihaela; Mada, Leonard; Stoicu-Tivadar, Lacramioara

2016-01-01

User interfaces are important to facilitate easy learning and operating with an IT application especially in the medical world. An easy to use interface has to be simple and to customize the user needs and mode of operation. The technology in the background is an important tool to accomplish this. The present work aims to creating a web interface using specific technology (HTML table design combined with CSS3) to provide an optimized responsive interface for a complex web application. In the first phase, the current icMED web medical application layout is analyzed, and its structure is designed using specific tools, on source files. In the second phase, a new graphic adaptable interface to different mobile terminals is proposed, (using HTML table design (TD) and CSS3 method) that uses no source files, just lines of code for layout design, improving the interaction in terms of speed and simplicity. For a complex medical software application a new prototype layout was designed and developed using HTML tables. The method uses a CSS code with only CSS classes applied to one or multiple HTML table elements, instead of CSS styles that can be applied to just one DIV tag at once. The technique has the advantage of a simplified CSS code, and a better adaptability to different media resolutions compared to DIV-CSS style method. The presented work is a proof that adaptive web interfaces can be developed just using and combining different types of design methods and technologies, using HTML table design, resulting in a simpler to learn and use interface, suitable for healthcare services.

Bespoke automation of medical workforce rostering using Google’s free cloud applications

Directory of Open Access Journals (Sweden)

Peter Benjamin Michael Thomas

2017-12-01

Full Text Available Background: Providing safe and consistent care requires optimal deployment of medical staff. Ensuring this happens is a significant administrative burden due to complex working patterns. Objective: To describe a pilot feasibility study of the automation of medical duty rostering in a busy tertiary Ophthalmology department. Methods: A cloud based web application was created using Google’s free cloud services. Users access the system via a website which hosts live rosters, and use electronic forms to submit requests which are automatically handled by Google App Scripts. Results: Over a 2-year period (8/2014-6/2016, the system processed 563 leave requests and 300 on call swaps automatically. 3,300 emails and 1,000 forms were automatically generated. User satisfaction was 100% (n=24. Discussion: Many time consuming aspects of roster management were automated with significant time savings to all parties, allowing increased clinical time for doctors involved in administration. Planning for safe staffing levels was supported.

8 CFR 245.5 - Medical examination.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Medical examination. 245.5 Section 245.5... THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 245.5 Medical examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by...

The application of digital medical 3D printing technology on tumor operation

Science.gov (United States)

Chen, Jimin; Jiang, Yijian; Li, Yangsheng

2016-04-01

Digital medical 3D printing technology is a new hi-tech which combines traditional medical and digital design, computer science, bio technology and 3D print technology. At the present time there are four levels application: The printed 3D model is the first and simple application. The surgery makes use of the model to plan the processing before operation. The second is customized operation tools such as implant guide. It helps doctor to operate with special tools rather than the normal medical tools. The third level application of 3D printing in medical area is to print artificial bones or teeth to implant into human body. The big challenge is the fourth level which is to print organs with 3D printing technology. In this paper we introduced an application of 3D printing technology in tumor operation. We use 3D printing to print guide for invasion operation. Puncture needles were guided by printed guide in face tumors operation. It is concluded that this new type guide is dominantly advantageous.

[Current teaching, learning and examination methods in medical education and potential applications in rehabilitative issues].

Science.gov (United States)

Schwarzkopf, S R; Morfeld, M; Gülich, M; Lay, W; Horn, K; Mau, W

2007-04-01

With introduction of the new Federal Medical Licensing Regulations (Approbationsordnung) in Germany, integrated teaching in "Rehabilitation, Physical Medicine, Naturopathic Treatment" (Querschnittsbereich Q12) has become obligatory for the first time. Furthermore, the new Regulations require the medical faculties in Germany to realize an innovative didactic orientation in teaching. This paper provides an overview of recent applications of teaching techniques and examination methods in medical education with special consideration of the new integrated course Q12 and further teaching methods related to rehabilitative issues. Problem-oriented learning (POL), problem-based learning (PBL), bedside teaching, eLearning, and the examination methods Objective Structured Clinical Examination (OSCE) and Triple Jump are in the focus. This overview is intended as the basis for subsequent publications of the Commission for Undergraduate and Postgraduate Training of the German Society of Rehabilitation Science (DGRW), which will present examples of innovative teaching material.

[Non-medical applications for brain MRI: Ethical considerations].

Science.gov (United States)

Sarrazin, S; Fagot-Largeault, A; Leboyer, M; Houenou, J

2015-04-01

The recent neuroimaging techniques offer the possibility to better understand complex cognitive processes that are involved in mental disorders and thus have become cornerstone tools for research in psychiatry. The performances of functional magnetic resonance imaging are not limited to medical research and are used in non-medical fields. These recent applications represent new challenges for bioethics. In this article we aim at discussing the new ethical issues raised by the applications of the latest neuroimaging technologies to non-medical fields. We included a selection of peer-reviewed English medical articles after a search on NCBI Pubmed database and Google scholar from 2000 to 2013. We screened bibliographical tables for supplementary references. Websites of governmental French institutions implicated in ethical questions were also screened for governmental reports. Findings of brain areas supporting emotional responses and regulation have been used for marketing research, also called neuromarketing. The discovery of different brain activation patterns in antisocial disorder has led to changes in forensic psychiatry with the use of imaging techniques with unproven validity. Automated classification algorithms and multivariate statistical analyses of brain images have been applied to brain-reading techniques, aiming at predicting unconscious neural processes in humans. We finally report the current position of the French legislation recently revised and discuss the technical limits of such techniques. In the near future, brain imaging could find clinical applications in psychiatry as diagnostic or predictive tools. However, the latest advances in brain imaging are also used in non-scientific fields raising key ethical questions. Involvement of neuroscientists, psychiatrists, physicians but also of citizens in neuroethics discussions is crucial to challenge the risk of unregulated uses of brain imaging. Copyright © 2014 L’Encéphale, Paris. Published by

37 CFR 1.81 - Drawings required in patent application.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Drawings required in patent..., DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.81 Drawings required in patent application. (a) The applicant for a patent is required to furnish...

Iso-Surface Volume Rendering : speed and accuracy for medical applications

NARCIS (Netherlands)

Bosma, Marco

2000-01-01

This thesis describes the research on the accuracy and speed of different methods for the visualization of three-dimensional (3D)sets of (measured) data. In medical environments, these 3D datasets are generated by for instance CT and MRI scanners. The medical application makes special demands on the

Optical polymers for laser medical applications

Science.gov (United States)

Sultanova, Nina G.; Kasarova, Stefka N.; Nikolov, Ivan D.

2016-01-01

In medicine, optical polymers are used not only in ophthalmology but in many laser surgical, diagnostic and therapeutic systems. The application in lens design is determined by their refractive and dispersive properties in the considered spectral region. We have used different measuring techniques to obtain precise refractometric data in the visible and near-infrared spectral regions. Dispersive, thermal and other important optical characteristics of polymers have been studied. Design of a plastic achromatic objective, used in a surgical stereo-microscope at 1064 nm laser wavelength, is accomplished. Geometrical and wavefront aberrations are calculated. Another example of application of polymers is the designed all-mirror apochromatic micro-lens, intended for superluminescent diode fiber coupling in medical systems.

RF linear accelerators for medical and industrial applications

CERN Document Server

Hanna, Samy

2012-01-01

This unique resource offers you a clear overview of medical and industrial accelerators. Using minimal mathematics, this book focuses on offering thorough explanations of basic concepts surrounding the operation of accelerators. you find well illustrated discussions designed to help you use accelerator-based systems in a safer, more productive, and more reliable manner.This practical book details the manufacturing process for producing accelerators for medical and industrial applications. You become knowledgeable about the commonly encountered real-world manufacturing issues and potential sources of defects which help you avoid costly production problems. From principles of operation and the role of accelerators in cancer radiation therapy, to manufacturing techniques and future trends in accelerator design and applications, this easy-to-comprehend volume quickly brings you up-to-speed with the critical concepts you need to understand for your work in the field.

Medical beam monitor—Pre-clinical evaluation and future applications

Science.gov (United States)

Frais-Kölbl, Helmut; Griesmayer, Erich; Schreiner, Thomas; Georg, Dietmar; Pernegger, Heinz

2007-10-01

Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

Medical beam monitor—Pre-clinical evaluation and future applications

CERN Document Server

Frais-Kölbl, H; Schreiner, T; Georg, D; Pernegger, H

2007-01-01

Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects

Science.gov (United States)

Prabhu, Sukumaran; Poulose, Eldho K.

2012-10-01

Silver nanoparticles are nanoparticles of silver which are in the range of 1 and 100 nm in size. Silver nanoparticles have unique properties which help in molecular diagnostics, in therapies, as well as in devices that are used in several medical procedures. The major methods used for silver nanoparticle synthesis are the physical and chemical methods. The problem with the chemical and physical methods is that the synthesis is expensive and can also have toxic substances absorbed onto them. To overcome this, the biological method provides a feasible alternative. The major biological systems involved in this are bacteria, fungi, and plant extracts. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications. In most of the therapeutic applications, it is the antimicrobial property that is being majorly explored, though the anti-inflammatory property has its fair share of applications. Though silver nanoparticles are rampantly used in many medical procedures and devices as well as in various biological fields, they have their drawbacks due to nanotoxicity. This review provides a comprehensive view on the mechanism of action, production, applications in the medical field, and the health and environmental concerns that are allegedly caused due to these nanoparticles. The focus is on effective and efficient synthesis of silver nanoparticles while exploring their various prospective applications besides trying to understand the current scenario in the debates on the toxicity concerns these nanoparticles pose.

IoT Applications with 5G Connectivity in Medical Tourism Sector Management: Third-Party Service Scenarios.

Science.gov (United States)

Psiha, Maria M; Vlamos, Panayiotis

2017-01-01

5G is the next generation of mobile communication technology. Current generation of wireless technologies is being evolved toward 5G for better serving end users and transforming our society. Supported by 5G cloud technology, personal devices will extend their capabilities to various applications, supporting smart life. They will have significant role in health, medical tourism, security, safety, and social life applications. The next wave of mobile communication is to mobilize and automate industries and industry processes via Machine-Type Communication (MTC) and Internet of Things (IoT). The current key performance indicators for the 5G infrastructure for the fully connected society are sufficient to satisfy most of the technical requirements in the healthcare sector. Thus, 5G can be considered as a door opener for new possibilities and use cases, many of which are as yet unknown. In this paper we present heterogeneous use cases in medical tourism sector, based on 5G infrastructure technologies and third-party cloud services.

Veterinary applications of ionising radiation HERCA Task Force on Veterinary Applications. Main results of the Questionnaire 'National regulatory requirements with regard to veterinary medical applications of ionising radiation' and conclusions of the TF

International Nuclear Information System (INIS)

Van Bladel, Lodewijk; Berlamont, Jolien; Michalczak, Herbert; Balogh, Lajos; Peremans, Kathelijne

2013-11-01

In the fall of 2012, the subject of radiation protection in veterinary medicine was raised during the meeting of the HERCA Board. Issues with regard to this subject had been brought to the attention of HERCA by the European College of Veterinary Diagnostic Imaging (ECVDI). In October 2012, the Board decided to charge a small Task Force (TF) to further explore the issues in this field. This TF drew up a questionnaire which looked at the general radiation protection regulatory requirements in veterinary medicine applications of ionizing radiation. The results of this study showed large differences in the requirements applicable in the HERCA member countries. The TF also noticed the increasing use of more complex imaging procedures and of different radio-therapeutic modalities, which may imply greater risks of exposure of humans to ionising radiation. These results were presented during the HERCA Board meeting in Berlin, Germany and on which the Board decided to establish a Working Group on veterinary applications of ionising radiations (WG Vet). The main results of the Questionnaire 'National regulatory requirements with regard to veterinary medicine applications of ionising radiation' is attached in Appendix

Design Requirements for Communication-Intensive Interactive Applications

Science.gov (United States)

Bolchini, Davide; Garzotto, Franca; Paolini, Paolo

Online interactive applications call for new requirements paradigms to capture the growing complexity of computer-mediated communication. Crafting successful interactive applications (such as websites and multimedia) involves modeling the requirements for the user experience, including those leading to content design, usable information architecture and interaction, in profound coordination with the communication goals of all stakeholders involved, ranging from persuasion to social engagement, to call for action. To face this grand challenge, we propose a methodology for modeling communication requirements and provide a set of operational conceptual tools to be used in complex projects with multiple stakeholders. Through examples from real-life projects and lessons-learned from direct experience, we draw on the concepts of brand, value, communication goals, information and persuasion requirements to systematically guide analysts to master the multifaceted connections of these elements as drivers to inform successful communication designs.

MyHealthAssistant: an event-driven middleware for multiple medical applications on a smartphone-mediated body sensor network.

Science.gov (United States)

Seeger, Christian; Van Laerhoven, Kristof; Buchmann, Alejandro

2015-03-01

An ever-growing range of wireless sensors for medical monitoring has shown that there is significant interest in monitoring patients in their everyday surroundings. It however remains a challenge to merge information from several wireless sensors and applications are commonly built from scratch. This paper presents a middleware targeted for medical applications on smartphone-like platforms that relies on an event-based design to enable flexible coupling with changing sets of wireless sensor units, while posing only a minor overhead on the resources and battery capacity of the interconnected devices. We illustrate the requirements for such middleware with three different healthcare applications that were deployed with our middleware solution, and characterize the performance with energy consumption, overhead caused for the smartphone, and processing time under real-world circumstances. Results show that with sensing-intensive applications, our solution only minimally impacts the phone's resources, with an added CPU utilization of 3% and a memory usage under 7 MB. Furthermore, for a minimum message delivery ratio of 99.9%, up to 12 sensor readings per second are guaranteed to be handled, regardless of the number of applications using our middleware.

Quality assurance in medical radiation applications. The medical and dental appointment; Qualitaetssicherung bei medizinischen Strahlenanwendungen. Die aerztlichen und zahnaerztlichen Stellen

Energy Technology Data Exchange (ETDEWEB)

Ernst-Elz, Andreas [Ministerium fuer Energiewende, Landwirtschaft, Umwelt, Natur und Digitalisierung des Landes Schleswig-Holstein, Kiel (Germany)

2017-07-01

Medical radiation applications cause averaged over the German population an annual exposure of almost 2 mSv. Medical authorities have the assignment to assure and control the diagnostic and therapeutic quality of these applications and to provide recommendations for operators with respect to dose reductions and radiation protection, including guidance for radiotherapy planning aimed to questions of dose and therapy optimization.

78 FR 19537 - SHINE Medical Technologies, Inc.; Exemption

Science.gov (United States)

2013-04-01

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0053] SHINE Medical Technologies, Inc.; Exemption AGENCY... Technologies, Inc. (SHINE) intends to submit an application to construct a medical isotope production facility... grants SHINE Medical Technologies, Inc. an exemption from the requirement of 10 CFR 2.101(a)(5) limiting...

Medical students' recognition and application of geriatrics principles in a new curriculum.

Science.gov (United States)

Nanda, Aman; Farrell, Timothy W; Shield, Renée R; Tomas, Maria; Campbell, Susan E; Wetle, Terrie

2013-03-01

Given the aging U.S. population, it is imperative that medical students recognize and apply geriatrics principles. To address this need, in 2006, the Warren Alpert Medical School of Brown University integrated geriatrics content into a new medical school curriculum. Preclinical and clinical medical students submitted written reflective journals in response to prompts regarding the geriatrics content of the new medical school curriculum, including their didactic and clinical experiences. An interdisciplinary team used a structured qualitative approach to identify themes, including the recognition and application of geriatrics principles. Thirty medical student journalers submitted 405 journal entries. Themes regarding students' emerging understanding of geriatrics principles included a growing understanding of geriatrics principles, recognition of the importance of psychosocial factors and patient preferences in caring for older adults, recognition of the complexities of treating older adults and application of geriatric principles to clinical situations, and understanding of physicians' roles in managing the care of older adults. Medical student reflective journaling allows medical educators to obtain timely feedback on curricular innovations and helps illuminate the process by which medical students learn to recognize and apply core geriatrics principles. © 2013, Copyright the Authors Journal compilation © 2013, The American Geriatrics Society.

Medical Device Integrated Vital Signs Monitoring Application with Real-Time Clinical Decision Support.

Science.gov (United States)

Moqeem, Aasia; Baig, Mirza; Gholamhosseini, Hamid; Mirza, Farhaan; Lindén, Maria

2018-01-01

This research involves the design and development of a novel Android smartphone application for real-time vital signs monitoring and decision support. The proposed application integrates market available, wireless and Bluetooth connected medical devices for collecting vital signs. The medical device data collected by the app includes heart rate, oxygen saturation and electrocardiograph (ECG). The collated data is streamed/displayed on the smartphone in real-time. This application was designed by adopting six screens approach (6S) mobile development framework and focused on user-centered approach and considered clinicians-as-a-user. The clinical engagement, consultations, feedback and usability of the application in the everyday practices were considered critical from the initial phase of the design and development. Furthermore, the proposed application is capable to deliver rich clinical decision support in real-time using the integrated medical device data.

Polymer Based Biosensors for Medical Applications

DEFF Research Database (Denmark)

Cherré, Solène; Rozlosnik, Noemi

2015-01-01

, environmental monitoring and food safety. The detected element varies from a single molecule (such as glucose), a biopolymer (such as DNA or a protein) to a whole organism (such as bacteria). Due to their easy use and possible miniaturization, biosensors have a high potential to come out of the lab...... and be available for use by everybody. To fulfil these purposes, polymers represent very appropriate materials. Many nano- and microfabrication methods for polymers are available, allowing a fast and cheap production of devices. This chapter will present the general concept of a biosensor in a first part......The objective of this chapter is to give an overview about the newest developments in biosensors made of polymers for medical applications. Biosensors are devices that can recognize and detect a target with high selectivity. They are widely used in many fields such as medical diagnostic...

78 FR 59038 - Mobile Medical Applications; Guidance for Industry and Food and Drug Administration Staff...

Science.gov (United States)

2013-09-25

... FDA intends to apply its regulatory oversight to only those mobile apps that are medical devices and...] Mobile Medical Applications; Guidance for Industry and Food and Drug Administration Staff; Availability...) is announcing the availability of the guidance entitled ``Mobile Medical Applications.'' The FDA is...

Public Use of Mobile Medical Applications: A Case Study on Cloud-Based Medical Service of Taiwan.

Science.gov (United States)

Lu, Chen-Luan; Yan, Yu-Hua

2016-01-01

The use of smart mobile devices has been getting increasingly popular. The focus of this study is an attempt to explore the development of mobile medical App by medical centers and regional hospitals of Taiwan and the function of the App for comparison. The results show indicated that many hospitals developed Apps for the public for mobile medical service, of which 26 medical centers (100%) and 72 regional hospitals (84.7%) availed appointment making service via Apps. The result indicated variance at significant level (p < 0.01). There are 23 medical centers (88.5%) and 74 regional hospitals (87.1%) availed Apps for checking service progress. The result indicated insignificant variance level (p > 0.01). We can see that mobile medical service is gradually emerging as a vital issue. Yet, this is a new domain in medical service. With the mushrooming of medical applications in smart mobile devices, the medical service system is expected to be installed in these devices to enhance interactive mode of operation and inquiry services, such as medication and inquiries into physical examination results. By then, people can learn the status of their health with this system.

The Most Common Smartphone Applications Used By Medical Students and Barriers of Using Them.

Science.gov (United States)

Jebraeily, Mohamad; Fazlollahi, Zahra Zare; Rahimi, Bahlol

2017-12-01

Medical knowledge is rapidly expanding and updating. It is very important that students can timely access to information and the latest scientific evidence without any time and place limitation. The smartphone is one of ICT tools that adopted greatly by healthcare professionals. Today, the most medical sciences universities have provided smartphone as an educational aid tool and acquisition licenses for medical apps resources in training of their students. This research was conducted to determine common smartphone applications among medical students of Urmia University of medical sciences and to identify barriers in using them. This research was a descriptive type of study carried out in 2016. Population of the study included 530 medical students completing the clinical course in Urmia University of Medical Sciences. Data were collected using researcher-developed questionnaire. The validity of it determined based on the view of experts and the reliability of it obtained by calculating the value of Cronbach's alpha (α = 0.82). 82.3% of the students had smartphone, which in terms of operating system the highest was related Andriod (53%) and iPhone (32%). The most common applications used often by medical students included Up to date, PubSearch, Calculate by QxMD, Epocrates and OMnio. Lack of accreditation of medical apps by valid health institutions (4.63), lack of support and update of applications by their developers (4.44), lack of adequate skill to use applications (4.25) are the most important barriers in using these applications among students. To assurance quality of medical apps, it seems very important that academic and healthcare organizations should be involved to develop and update the apps and also provided guidelines for accreditation of apps. It is recommended that for promotion of knowledge and skill of students provide essential educations.

Regression methods for medical research

CERN Document Server

Tai, Bee Choo

2013-01-01

Regression Methods for Medical Research provides medical researchers with the skills they need to critically read and interpret research using more advanced statistical methods. The statistical requirements of interpreting and publishing in medical journals, together with rapid changes in science and technology, increasingly demands an understanding of more complex and sophisticated analytic procedures.The text explains the application of statistical models to a wide variety of practical medical investigative studies and clinical trials. Regression methods are used to appropriately answer the

Summaries of fiscal year 1994 projects in medical applications and biophysical research

International Nuclear Information System (INIS)

1995-04-01

This report provides information on the research supported in Fiscal Year 1994 by the Medical Applications and Biophysical Research Division of the Office of Health and Environmental Research. A brief statement of the scope of the following areas is presented: dosimetry; measurement science; radiological and chemical physics; structural biology; human genome; and medical applications. Summaries of the research projects in these categories are presented

Johnson Space Center Health and Medical Technical Authority

Science.gov (United States)

Fogarty, Jennifer A.

2010-01-01

1.HMTA responsibilities: a) Assure program/project compliance with Agency health and medical requirements at identified key decision points. b) Certify that programs/projects comply with Agency health and medical requirements prior to spaceflight missions. c) Assure technical excellence. 2. Designation of applicable NASA Centers for HMTA implementation and Chief Medical Officer (CMO) appointment. 3. Center CMO responsible for HMTA implementation for programs and projects at the center. JSC HMTA captured in "JSC HMTA Implementation Plan". 4. Establishes specifics of dissenting opinion process consistent with NASA procedural requirements.

Examining changes in certification/licensure requirements and the international medical graduate examinee pool.

Science.gov (United States)

McKinley, Danette W; Hess, Brian J; Boulet, John R; Lipner, Rebecca S

2014-03-01

Changes in certification requirements and examinee characteristics are likely to influence the validity of the evidence associated with interpretations made based on test data. We examined whether changes in Educational Commission for Foreign Medical Graduates (ECFMG) certification requirements over time were associated with changes in internal medicine (IM) residency program director ratings and certification examination scores. Comparisons were made between physicians who were ECFMG-certified before and after the Clinical Skills Assessment (CSA) requirement. A multivariate analysis of covariance was conducted to examine the differences in program director ratings based on CSA cohort and whether the examinees emigrated for undergraduate medical education (national vs. international students). A univariate analysis of covariance was conducted to examine differences in scores from the American Board of Internal Medicine (ABIM) Internal Medicine Certification Examination. For both analyses, United States Medical Licensing Examination (USMLE) Step 1 and Step 2 scores were used as covariates. Results indicate that, of those certified by ECFMG between 1993 and 1997, 17 % (n = 1,775) left their country of citizenship for undergraduate medical education. In contrast, 38 % (n = 1,874) of those certified between 1999 and 2003 were international students. After adjustment by covariates, the main effect of cohort membership on the program director ratings was statistically significant (Wilks' λ = 0.99, F 5, 15391 = 19.9, P migration status was statistically significant and weak (Wilks' λ = 0.98, F 5,15391 = 45.3, P Internal Medicine Certification Examination scores based on whether or not CSA were required was statistically significant, although the magnitude of the association between these variables was very small. The findings suggest that the implementation of an additional evaluation of skills (e.g., history-taking, physical examination) as a

18 CFR 157.15 - Requirements for applications covering acquisitions.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Requirements for... Requirements for applications covering acquisitions. An application for a certificate authorizing acquisition... all of vendor's facilities. (e) Any franchise, license, or permit respecting the facilities involved...

Evaluation of HVS models in the application of medical image quality assessment

Science.gov (United States)

Zhang, L.; Cavaro-Menard, C.; Le Callet, P.

2012-03-01

In this study, four of the most widely used Human Visual System (HVS) models are applied on Magnetic Resonance (MR) images for signal detection task. Their performances are evaluated against gold standard derived from radiologists' majority decision. The task-based image quality assessment requires taking into account the human perception specificities, for which various HVS models have been proposed. However to our knowledge, no work was conducted to evaluate and compare the suitability of these models with respect to the assessment of medical image qualities. This pioneering study investigates the performances of different HVS models on medical images in terms of approximation to radiologist performance. We propose to score the performance of each HVS model using the AUC (Area Under the receiver operating characteristic Curve) and its variance estimate as the figure of merit. The radiologists' majority decision is used as gold standard so that the estimated AUC measures the distance between the HVS model and the radiologist perception. To calculate the variance estimate of AUC, we adopted the one-shot method that is independent of the HVS model's output range. The results of this study will help to provide arguments to the application of some HVS model on our future medical image quality assessment metric.

Aliphatic polyesters for medical imaging and theranostic applications.

Science.gov (United States)

Nottelet, Benjamin; Darcos, Vincent; Coudane, Jean

2015-11-01

Medical imaging is a cornerstone of modern medicine. In that context the development of innovative imaging systems combining biomaterials and contrast agents (CAs)/imaging probes (IPs) for improved diagnostic and theranostic applications focuses intense research efforts. In particular, the classical aliphatic (co)polyesters poly(lactide) (PLA), poly(lactide-co-glycolide) (PLGA) and poly(ɛ-caprolactone) (PCL), attract much attention due to their long track record in the medical field. This review aims therefore at providing a state-of-the-art of polyester-based imaging systems. In a first section a rapid description of the various imaging modalities, including magnetic resonance imaging (MRI), optical imaging, computed tomography (CT), ultrasound (US) and radionuclide imaging (SPECT, PET) will be given. Then, the two main strategies used to combine the CAs/IPs and the polyesters will be discussed. In more detail we will first present the strategies relying on CAs/IPs encapsulation in nanoparticles, micelles, dendrimers or capsules. We will then present chemical modifications of polyesters backbones and/or polyester surfaces to yield macromolecular imaging agents. Finally, opportunities offered by these innovative systems will be illustrated with some recent examples in the fields of cell labeling, diagnostic or theranostic applications and medical devices. Copyright © 2015 Elsevier B.V. All rights reserved.

Radiological protection, safety and security issues in the industrial and medical applications of radiation sources

Science.gov (United States)

Vaz, Pedro

2015-11-01

The use of radiation sources, namely radioactive sealed or unsealed sources and particle accelerators and beams is ubiquitous in the industrial and medical applications of ionizing radiation. Besides radiological protection of the workers, members of the public and patients in routine situations, the use of radiation sources involves several aspects associated to the mitigation of radiological or nuclear accidents and associated emergency situations. On the other hand, during the last decade security issues became burning issues due to the potential malevolent uses of radioactive sources for the perpetration of terrorist acts using RDD (Radiological Dispersal Devices), RED (Radiation Exposure Devices) or IND (Improvised Nuclear Devices). A stringent set of international legally and non-legally binding instruments, regulations, conventions and treaties regulate nowadays the use of radioactive sources. In this paper, a review of the radiological protection issues associated to the use of radiation sources in the industrial and medical applications of ionizing radiation is performed. The associated radiation safety issues and the prevention and mitigation of incidents and accidents are discussed. A comprehensive discussion of the security issues associated to the global use of radiation sources for the aforementioned applications and the inherent radiation detection requirements will be presented. Scientific, technical, legal, ethical, socio-economic issues are put forward and discussed.

A Joint Force Medical Command is Required to Fix Combat Casualty Care

Science.gov (United States)

2017-10-05

DISTRIBUTION STATEMENT: A Approved for Public Release Distribution is Unlimited The views expressed herein are those of the author(s) and do not...MHS) is required to provide medical operational forces for military and contingency operations while also providing services that maintain a healthy...provide timely support of joint forcible entry or other contingencies requiring rapid response. Further, the complexity and cost of the beneficiary

Job requirements compared to medical school education: differences between graduates from problem-based learning and conventional curricula

Directory of Open Access Journals (Sweden)

Federkeil Gero

2010-01-01

Full Text Available Abstract Background Problem-based Learning (PBL has been suggested as a key educational method of knowledge acquisition to improve medical education. We sought to evaluate the differences in medical school education between graduates from PBL-based and conventional curricula and to what extent these curricula fit job requirements. Methods Graduates from all German medical schools who graduated between 1996 and 2002 were eligible for this study. Graduates self-assessed nine competencies as required at their day-to-day work and as taught in medical school on a 6-point Likert scale. Results were compared between graduates from a PBL-based curriculum (University Witten/Herdecke and conventional curricula. Results Three schools were excluded because of low response rates. Baseline demographics between graduates of the PBL-based curriculum (n = 101, 49% female and the conventional curricula (n = 4720, 49% female were similar. No major differences were observed regarding job requirements with priorities for "Independent learning/working" and "Practical medical skills". All competencies were rated to be better taught in PBL-based curriculum compared to the conventional curricula (all p Conclusion Among medical graduates in Germany, PBL demonstrated benefits with regard to competencies which were highly required in the job of physicians. Research and business competence deserve closer attention in future curricular development.

Near-infrared spectroscopic tissue imaging for medical applications

Science.gov (United States)

Demos, Stavros [Livermore, CA; Staggs, Michael C [Tracy, CA

2006-12-12

Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

Radiotracers for medical applications

International Nuclear Information System (INIS)

Rayudu, G.A.S.

1983-01-01

This book discusses the medical applications of radiotracers. Diagnostic uses and pharmacokinetics of isotopes and radiopharmaceuticals is emphasized. The volume one covers the following topics: Radiohalogenated compounds, including radioiodine; Tc-labeled compounds; and in-house prepared radiopharmaceuticals. The charge particle range vs. energy in every element is tabulated for protons for cyclotrons users. Discussions are also provided on nonimaging radiotracer methods; /sup 11/C, /sup 13/N, /sup 15/O, /sup 67/Ga. /sup 111/In, /sup 75/Se, /sup 123m/Te compounds; radioactive noble gases; and miscellaneous radiotracers for imaging. Vol. II: Pertinent nuclear science data such as radiation dosimetry, radionuclide production modes, radionuclides for therapy, human experimentation regulations and consent forms, and radiotracer laboratory designs are presented. 272 pp., 7 x 10, 1983, ISBN-0-8493-6016-1

Principles for new optical techniques in medical diagnostics for mHealth applications

Science.gov (United States)

Balsam, Joshua Michael

Medical diagnostics is a critical element of effective medical treatment. However, many modern and emerging diagnostic technologies are not affordable or compatible with the needs and conditions found in low-income and middle-income countries and regions. Resource-poor areas require low-cost, robust, easy-to-use, and portable diagnostics devices compatible with telemedicine (i.e. mHealth) that can be adapted to meet diverse medical needs. Many suitable devices will need to be based on optical technologies, which are used for many types of biological analyses. This dissertation describes the fabrication and detection principles for several low-cost optical technologies for mHealth applications including: (1) a webcam based multi-wavelength fluorescence plate reader, (2) a lens-free optical detector used for the detection of Botulinum A neurotoxin activity, (3) a low cost micro-array reader that allows the performance of typical fluorescence based assays demonstrated for the detection of the toxin staphylococcal enterotoxin (SEB), and (4) a wide-field flow cytometer for high throughput detection of fluorescently labeled rare cells. This dissertation discusses how these technologies can be harnessed using readily available consumer electronics components such as webcams, cell phones, CCD cameras, LEDs, and laser diodes. There are challenges in developing devices with sufficient sensitivity and specificity, and approaches are presented to overcoming these challenges to create optical detectors that can serve as low cost medical diagnostics in resource-poor settings for mHealth.

21 CFR 801.128 - Exceptions or alternatives to labeling requirements for medical devices held by the Strategic...

Science.gov (United States)

2010-04-01

... requirements for medical devices held by the Strategic National Stockpile. 801.128 Section 801.128 Food and... requirements for medical devices held by the Strategic National Stockpile. (a) The appropriate FDA Center... Strategic National Stockpile. (b)(1)(i) A Strategic National Stockpile official or any entity that...

Field-testing the new DECtalk PC system for medical applications

Science.gov (United States)

Grams, R. R.; Smillov, A.; Li, B.

1992-01-01

Synthesized human speech has now reached a new level of performance. With the introduction of DEC's new DECtalk PC, the small system developer will have a very powerful tool for creative design. It has been our privilege to be involved in the beta-testing of this new device and to add a medical dictionary which covers a wide range of medical terminology. With the inherent board level understanding of speech synthesis and the medical dictionary, it is now possible to provide full digital speech output for all medical files and terms. The application of these tools will cover a wide range of options for the future and allow a new dimension in dealing with the complex user interface experienced in medical practice.

Medical Physics Residency Consortium: collaborative endeavors to meet the ABR 2014 certification requirements

Science.gov (United States)

Parker, Brent C.; Duhon, John; Yang, Claus C.; Wu, H. Terry; Hogstrom, Kenneth R.

2014-01-01

In 2009, Mary Bird Perkins Cancer Center (MBPCC) established a Radiation Oncology Physics Residency Program to provide opportunities for medical physics residency training to MS and PhD graduates of the CAMPEP‐accredited Louisiana State University (LSU)‐MBPCC Medical Physics Graduate Program. The LSU‐MBPCC Program graduates approximately six students yearly, which equates to a need for up to twelve residency positions in a two‐year program. To address this need for residency positions, MBPCC has expanded its Program by developing a Consortium consisting of partnerships with medical physics groups located at other nearby clinical institutions. The consortium model offers the residents exposure to a broader range of procedures, technology, and faculty than available at the individual institutions. The Consortium institutions have shown a great deal of support from their medical physics groups and administrations in developing these partnerships. Details of these partnerships are specified within affiliation agreements between MBPCC and each participating institution. All partner sites began resident training in 2011. The Consortium is a network of for‐profit, nonprofit, academic, community, and private entities. We feel that these types of collaborative endeavors will be required nationally to reach the number of residency positions needed to meet the 2014 ABR certification requirements and to maintain graduate medical physics training programs. PACS numbers: 01.40.Fk, 01.40.gb PMID:24710434

Severe hypoglycaemia requiring the assistance of emergency medical services - frequency, causes and symptoms

Czech Academy of Sciences Publication Activity Database

Krnačová, V.; Kuběna, Aleš Antonín; Macek, K.; Bezděk, M.; Šmahelová, A.; Vlček, J.

2012-01-01

Roč. 156, č. 3 (2012), s. 271-277 ISSN 1213-8118 Grant - others:GA UK(CZ) SVV-2010-261-004 Keywords : regression trees * causes * symptoms * incidence * emergency medical service * severe hypoglycaemia Subject RIV: EI - Biotechnology ; Bionics Impact factor: 0.990, year: 2012 http://library.utia.cas.cz/separaty/2013/E/kubena-severe hypoglycaemia requiring the assistance of emergency medical services - frequency causes and symptoms.pdf

21 CFR 1311.120 - Electronic prescription application requirements.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Electronic prescription application requirements. 1311.120 Section 1311.120 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... application must clear the plain text password from the application memory to prevent the unauthorized access...

31 CFR 50.24 - Applicability of State law requirements.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Applicability of State law requirements. 50.24 Section 50.24 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Mandatory Availability § 50.24 Applicability of State law requirements. (a...

24 CFR 35.925 - Examples of determining applicable requirements.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Examples of determining applicable requirements. 35.925 Section 35.925 Housing and Urban Development Office of the Secretary, Department of... Rehabilitation § 35.925 Examples of determining applicable requirements. The following examples illustrate how to...

Utilization of smart phones related medical applications among medical students at King Abdulaziz University, Jeddah: A cross-sectional study.

Science.gov (United States)

Sayedalamin, Zaid; Alshuaibi, Abdulaziz; Almutairi, Osama; Baghaffar, Mariam; Jameel, Tahir; Baig, Mukhtiar

The present study explored the utility, attitude, and trends regarding Smartphone related Medical Applications (Apps) among medical students of King Abdulaziz University (KAU) Jeddah, Saudi Arabia (SA) and their perceptions of the impact of Medical Apps in their training activities. This survey was conducted at the Faculty of Medicine, Jeddah, and Rabigh campuses, KAU, Jeddah, SA. All participants were medical students of 2nd to 6th year. The data was collected by using an anonymous questionnaire regarding the perception of medical students about Medical Apps on the smart devices and the purpose of installation of the Apps. Additionally examined was the use of different Medical Apps by the students to investigate the impact of Medical Apps on the clinical training/practice. Data was analyzed on SPSS 21. The opinion of 330/460 medical students from all academic years was included in the study with a response rate of 72%. There were 170 (51.5%) males and 160 (48.5%) females with a mean age of 21.26±1.86 years. Almost all participating students 320 (97%) were well aware of Medical Apps for smart devices and 89.1% had installed different applications on their smart devices. The main usage was for either revision of courses (62.4%) or for looking up of medical information (67.3%), followed by preparing for a presentation (34.5%) and getting the medical news (32.1%). Regarding the impact of Medical Apps, most of the students considered these helpful in clinical decision-making, assisting in differential diagnosis, allowing faster access to Evidence-Based Medical practice, saving time and others. The practical use of these Apps was found to be minimal in medical students. Around 73% were occasional users of Medical Apps, and only 27% were using Medical Apps at least once a day. The regular use of Medical Apps on mobile devices is not common among medical students of KAU. Copyright © 2016 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd

Multimedia Security System for Security and Medical Applications

Science.gov (United States)

Zhou, Yicong

2010-01-01

This dissertation introduces a new multimedia security system for the performance of object recognition and multimedia encryption in security and medical applications. The system embeds an enhancement and multimedia encryption process into the traditional recognition system in order to improve the efficiency and accuracy of object detection and…

Do medical students require education on issues related to plagiarism?

Science.gov (United States)

Varghese, Joe; Jacob, Molly

2015-01-01

In the course of our professional experience, we have seen that many medical students plagiarise. We hypothesised that they do so out of ignorance and that they require formal education on the subject. With this objective in mind, we conducted a teaching session on issues related to plagiarism. As a part of this, we administered a quiz to assess their baseline knowledge on plagiarism and a questionnaire to determine their attitudes towards it. We followed this up with an interactive teaching session, in which we discussed various aspects of plagiarism. We subjected the data obtained from the quiz and questionnaire to bivariate and multivariate analysis. A total of 423 medical students participated in the study. Their average score for the quiz was 4.96±1.67 (out of 10). Age, gender and years in medical school were not significantly associated with knowledge regarding plagiarism. The knowledge scores were negatively correlated with permissive attitudes towards plagiarism and positively correlated with attitudes critical of the practice. Men had significantly higher scores on permissive attitudes compared to women . In conclusion, we found that the medical students' knowledge regarding plagiarism was limited. Those with low knowledge scores tended to have permissive attitudes towards plagiarism and were less critical of the practice. We recommend the inclusion of formal instruction on this subject in the medical curriculum, so that this form of academic misconduct can be tackled.

Medical imaging technology reviews and computational applications

CERN Document Server

Dewi, Dyah

2015-01-01

This book presents the latest research findings and reviews in the field of medical imaging technology, covering ultrasound diagnostics approaches for detecting osteoarthritis, breast carcinoma and cardiovascular conditions, image guided biopsy and segmentation techniques for detecting lung cancer, image fusion, and simulating fluid flows for cardiovascular applications. It offers a useful guide for students, lecturers and professional researchers in the fields of biomedical engineering and image processing.

31 CFR 223.6 - Requirements applicable to surety companies.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Requirements applicable to surety companies. 223.6 Section 223.6 Money and Finance: Treasury Regulations Relating to Money and Finance... BUSINESS WITH THE UNITED STATES § 223.6 Requirements applicable to surety companies. Every company now or...

76 FR 50231 - Mobile Medical Applications Draft Guidance; Public Workshop

Science.gov (United States)

2011-08-12

... workshop discussion, a ``mobile medical app'' is a mobile application that meets the definition of ``device... applications are subject to regulation as devices when they meet the definition of a device in section 201(h... man * * * '' or ``* * * intended to affect the structure or any function of the body of man or other...

A Preoperative Medical History and Physical Should Not Be a Requirement for All Cataract Patients.

Science.gov (United States)

Schein, Oliver D; Pronovost, Peter J

2017-07-01

Cataract surgery poses minimal systemic medical risk, yet a preoperative general medical history and physical is required by the Centers for Medicare and Medicaid Services and other regulatory bodies within 1 month of cataract surgery. Based on prior research and practice guidelines, there is professional consensus that preoperative laboratory testing confers no benefit when routinely performed on cataract surgical patients. Such testing remains commonplace. Although not yet tested in a large-scale trial, there is also no evidence that the required history and physical yields a benefit for most cataract surgical patients above and beyond the screening performed by anesthesia staff on the day of surgery. We propose that the minority of patients who might benefit from a preoperative medical history and physical can be identified prospectively. Regulatory agencies should not constrain medical practice in a way that adds enormous cost and patient burden in the absence of value.

Application of Learning Theories on Medical Imaging Education

Directory of Open Access Journals (Sweden)

Osama A. Mabrouk Kheiralla

2018-05-01

Full Text Available The main objective of the education process is that student must learn well rather than the educators to teach well. If radiologists get involved in the process of medical education, it is important for them to do it through sound knowledge of how students learn. Researches have proved that most of the teachers in the field of medical education including diagnostic imaging are actually doctors or technicians, who didn’t have an opportunity to study the basics of learning. Mostly they have gained their knowledge through watching other educators, and they mostly rely on their personal skills and experience in doing their job. This will hinder them from conveying knowledge in an effective and scientific way, and they will find themselves lagging away behind the latest advances in the field of medical education and educational research, which will lead to negative cognitive outcomes among learners. This article presents an overview of three of the most influential basic theories of learning, upon which many teachers rely in their practical applications, which must be considered by radiologist who act as medical educators.

Rape as a legal indication for abortion: implications and consequences of the medical examination requirement.

Science.gov (United States)

Teklehaimanot, K I; Smith, C Hord

2004-01-01

A number of countries adopt abortion laws recognizing rape as a legal ground for access to safe abortion service. As rape is a crime, these abortion laws carry with them criminal and health care elements that in turn result in the involvement of legal and medical expertise. The most common objective of the laws should be providing safe abortion services to women survivors of rape. Depending on purposes of a given abortion law, the laws usually require women to undergo a medical examination to qualify for a legal abortion. Some abortion laws are so vague as to result in uncertainties regarding the steps health personnel must follow in conducting medical examination. Another group of abortion laws do not leave room for regulation and remain too rigid to respond to changing socio-economic circumstances. Still others require medical examination as a prerequisite for abortion. As a result, a number of abortion laws remain on the books. The paper attempts to analyze legal and practical issues related to medical examination in rape cases.

NASA technology utilization applications. [transfer of medical sciences

Science.gov (United States)

1973-01-01

The work is reported from September 1972 through August 1973 by the Technology Applications Group of the Science Communication Division (SCD), formerly the Biological Sciences Communication Project (BSCP) in the Department of Medical and Public Affairs of the George Washington University. The work was supportive of many aspects of the NASA Technology Utilization program but in particular those dealing with Biomedical and Technology Application Teams, Applications Engineering projects, new technology reporting and documentation and transfer activities. Of particular interest are detailed reports on the progress of various hardware projects, and suggestions and criteria for the evaluation of candidate hardware projects. Finally some observations about the future expansion of the TU program are offered.

Virtual Reality in Psychological, Medical and Pedagogical Applications

Science.gov (United States)

Eichenberg, Christiane, Ed.

2012-01-01

This book has an aim to present latest applications, trends and developments of virtual reality technologies in three humanities disciplines: in medicine, psychology and pedagogy. Studies show that people in both educational as well as in the medical therapeutic range expect more and more that modern media are included in the corresponding demand…

Three-Dimensional Printing and Medical Imaging: A Review of the Methods and Applications.

Science.gov (United States)

Marro, Alessandro; Bandukwala, Taha; Mak, Walter

2016-01-01

The purpose of this article is to review recent innovations on the process and application of 3-dimensional (3D) printed objects from medical imaging data. Data for 3D printed medical models can be obtained from computed tomography, magnetic resonance imaging, and ultrasound using the Data Imaging and Communications in Medicine (DICOM) software. The data images are processed using segmentation and mesh generation tools and converted to a standard tessellation language (STL) file for printing. 3D printing technologies include stereolithography, selective laser sintering, inkjet, and fused-deposition modeling . 3D printed models have been used for preoperative planning of complex surgeries, the creation of custom prosthesis, and in the education and training of physicians. The application of medical imaging and 3D printers has been successful in providing solutions to many complex medical problems. As technology advances, its applications continue to grow in the future. Copyright © 2015 Mosby, Inc. All rights reserved.

8 CFR 1245.5 - Medical examination.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Medical examination. 1245.5 Section 1245.5... examination. Pursuant to section 232(b) of the Act, an applicant for adjustment of status shall be required to have a medical examination by a designated civil surgeon, whose report setting forth the findings of...

OSHA medical and workplace surveillance requirements and NIOSH recommendations (for employees exposed to toxic substances and other work hazards)

Science.gov (United States)

Cooper, L. P.

1983-01-01

Both OSHA medical and work place surveillance requirements and NIOSH recommendations were prepared as a desk reference to help occupational health professionals to perform their duties. The medical surveillance information focuses on frequency of physical examinations, specific problems that may arise as a result of exposure (e.g., decreased immunocompetence, weight loss, ets.), conditions that intensify the harmful effects of exposure (e.g., medication an exposed employee may be taking, cigarette smoking, etc.), the areas that should be scrutinized in medical and work histories and during the physical exam, and specific clinical tests that should be conducted. Recordkeeping requirements are also specified. The workplace surveillance information consists of monitoring requirements, personal protective equipment requirements, and recordkeeping requirements. Such details as the sampling devices that should be used, the type of respirators that should be worn, and the frequency of inspections are included. This document does not specify the training, labeling and posting, and safe work practice requirements and recommendations due to space considerations.

Medical Applications at CERN and the ENLIGHT Network.

Science.gov (United States)

Dosanjh, Manjit; Cirilli, Manuela; Myers, Steve; Navin, Sparsh

2016-01-01

State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centers: from imaging technologies to dedicated accelerators for cancer therapy and nuclear medicine, simulations, and data analytics. Principles of particle physics themselves are the foundation of a cutting edge radiotherapy technique for cancer treatment: hadron therapy. This article is an overview of the involvement of CERN, the European Organization for Nuclear Research, in medical applications, with specific focus on hadron therapy. It also presents the history, achievements, and future scientific goals of the European Network for Light Ion Hadron Therapy, whose co-ordination office is at CERN.

Design and Evaluation of a Medication Adherence Application with Communication for Seniors in Independent Living Communities.

Science.gov (United States)

Dasgupta, Dipanwita; Johnson, Reid A; Chaudhry, Beenish; Reeves, Kimberly G; Willaert, Patty; Chawla, Nitesh V

2016-01-01

Medication non-adherence is a pressing concern among seniors, leading to a lower quality of life and higher healthcare costs. While mobile applications provide a viable medium for medication management, their utility can be limited without tackling the specific needs of seniors and facilitating the active involvement of care providers. To address these limitations, we are developing a tablet-based application designed specifically for seniors to track their medications and a web portal for their care providers to track medication adherence. In collaboration with a local Aging in Place program, we conducted a three-month study with sixteen participants from an independent living facility. Our study found that the application helped participants to effectively track their medications and improved their sense of wellbeing. Our findings highlight the importance of catering to the needs of seniors and of involving care providers in this process, with specific recommendations for the development of future medication management applications.

45 CFR 1326.19 - Application requirements.

Science.gov (United States)

2010-10-01

... INDIAN TRIBES FOR SUPPORT AND NUTRITION SERVICES § 1326.19 Application requirements. A tribal... ability of the tribal organization to deliver supportive and nutrition services to older Indians, or documentation that the tribal organization has effectively administered supportive and nutrition services within...

Using Simulation-Based Medical Education to Meet the Competency Requirements for the Single Accreditation System.

Science.gov (United States)

Riley, Bernadette

2015-08-01

Simulation-based medical education can provide medical training in a nonjudgmental, patient-safe, and effective environment. Although simulation has been a relatively new addition to medical education, the aeronautical, judicial, and military fields have used simulation training for hundreds of years, with positive outcomes. Simulation-based medical education can be used in a variety of settings, such as hospitals, outpatient clinics, medical schools, and simulation training centers. As the author describes in the present article, residencies currently accredited by the American Osteopathic Association can use a simulation-based medical education curriculum to meet training requirements of the 6 competencies identified by the Accreditation Council for Graduate Medical Education. The author also provides specific guidance on providing training and assessment in the professionalism competency.

The influence of labor market changes on first-time medical school applicant pools.

Science.gov (United States)

Cort, David A; Morrison, Emory

2014-12-01

To explore whether the number and composition of first-time applicants to U.S. MD-granting medical schools, which have fluctuated over the past 30 years, are related to changes in labor market strength, specifically the unemployment rate and wages. The authors merged time series data from 1980 through 2010 (inclusive) from five sources and used multivariate time series models to determine whether changes in labor market strength (and several other macro-level factors) were related to the number of the medical school applicants as reported by the American Medical College Application Service. Analyses were replicated across specific sex and race/ethnicity applicant pools. Two results surfaced in the analyses. First, the strength of the labor market was not influential in explaining changes in applicant pool sizes for all applicants, but was strongly influential in explaining changes for black and Hispanic males. Increases of $1,000 in prevailing median wages produced a 1.6% decrease in the white male applicant pool, while 1% increases in the unemployment rate were associated with 4.5% and 3.1% increases in, respectively, the black and Hispanic male applicant pools. Second, labor market strength was a more important determinant in applications from males than in applications from females. Although stakeholders cannot directly influence the overall economic market, they can plan and prepare for fewer applications from males, especially those who are black and Hispanic, when the labor market is strong.

Usability Evaluation of An Electronic Medication Administration Record (eMAR) Application

Science.gov (United States)

Guo, J.; Iribarren, S.; Kapsandoy, S.; Perri, S.; Staggers, N.

2011-01-01

Background Electronic medication administration records (eMARs) have been widely used in recent years. However, formal usability evaluations are not yet available for these vendor applications, especially from the perspective of nurses, the largest group of eMAR users. Objective To conduct a formal usability evaluation of an implemented eMAR. Methods Four evaluators examined a commercial vendor eMAR using heuristic evaluation techniques. The evaluators defined seven tasks typical of eMAR use and independently evaluated the application. Consensus techniques were used to obtain 100% agreement of identified usability problems and severity ratings. Findings were reviewed with 5 clinical staff nurses and the Director of Clinical Informatics who verified findings with a small group of clinical nurses. Results Evaluators found 60 usability problems categorized into 233 heuristic violations. Match, Error, and Visibility heuristics were the most frequently violated. Administer Medication and Order and Modify Medications tasks had the highest number of heuristic violations and usability problems rated as major or catastrophic. Conclusion The high number of usability problems could impact the effectiveness, efficiency and satisfaction of nurses’ medication administration activities and may include concerns about patient safety. Usability is a joint responsibility between sites and vendors. We offer a call to action for usability evaluations at all sites and eMAR application redesign as necessary to improve the user experience and promote patient safety. PMID:23616871

Regulation EM-ER-6. Requirements for the realization of clinical essays to the medical equipments

International Nuclear Information System (INIS)

2015-01-01

This regulation applies to the medical equipment that become incorporated to the stage of clinical trial required for its evaluation and record, for which they are subdued to clinical investigation for the sake of verifying, in conditions specified of use, its functioning, identifying besides any undesirable defect. It extends to manufacturers of medical equipments, Public Health's units where the clinical investigations with those equipments take place and to the rest of the entities of the MINSAP . Its objective is to protect the participating subjects in the clinical investigations; Assuring the conduction of the clinical investigation and specifying the requirements for the conduction of the clinical investigations and the documentation required for it.

Unusual events in the use of radioactive material at medical applications

International Nuclear Information System (INIS)

Czarwinski, R.

2002-01-01

In the Federal Republic of Germany unusual events in the use of radioactive materials and in the operation of accelerators outside the nuclear sector are evaluated centrally and published annually. At that evaluation it can be distinguished between the medical and non-medical application of ionising radiation. Around 3000 user of radioactive materials are registered in medicine including research and teaching. That means approximately 25% of all users in Germany. Firstly an overview on the number of unusual events in the last ten years is given for medical applications like afterloading, gamma irradiation, nuclear medicine, radiation sources and accelerators. The analysis of the incidents in the considered medical areas resulted in two categories-human error and technical break down. The main causes for the incidents which could be analysed are presented in the paper. Additionally the radiation exposures resulting from the incidents are considered. The analysis of these unusual events enables in dependence of the known information lessons learned to avoid similar errors. This feedback will be offered. (Author)

Job requirements compared to medical school education: differences between graduates from problem-based learning and conventional curricula.

Science.gov (United States)

Schlett, Christopher L; Doll, Hinnerk; Dahmen, Janosch; Polacsek, Ole; Federkeil, Gero; Fischer, Martin R; Bamberg, Fabian; Butzlaff, Martin

2010-01-14

Problem-based Learning (PBL) has been suggested as a key educational method of knowledge acquisition to improve medical education. We sought to evaluate the differences in medical school education between graduates from PBL-based and conventional curricula and to what extent these curricula fit job requirements. Graduates from all German medical schools who graduated between 1996 and 2002 were eligible for this study. Graduates self-assessed nine competencies as required at their day-to-day work and as taught in medical school on a 6-point Likert scale. Results were compared between graduates from a PBL-based curriculum (University Witten/Herdecke) and conventional curricula. Three schools were excluded because of low response rates. Baseline demographics between graduates of the PBL-based curriculum (n = 101, 49% female) and the conventional curricula (n = 4720, 49% female) were similar. No major differences were observed regarding job requirements with priorities for "Independent learning/working" and "Practical medical skills". All competencies were rated to be better taught in PBL-based curriculum compared to the conventional curricula (all p learning/working" (Delta + 0.57), "Psycho-social competence" (Delta + 0.56), "Teamwork" (Delta + 0.39) and "Problem-solving skills" (Delta + 0.36), whereas "Research competence" (Delta--1.23) and "Business competence" (Delta--1.44) in the PBL-based curriculum needed improvement. Among medical graduates in Germany, PBL demonstrated benefits with regard to competencies which were highly required in the job of physicians. Research and business competence deserve closer attention in future curricular development.

New non-cognitive procedures for medical applicant selection: a qualitative analysis in one school.

Science.gov (United States)

Katz, Sara; Vinker, Shlomo

2014-11-07

Recent data have called into question the reliability and predictive validity of standard admission procedures to medical schools. Eliciting non-cognitive attributes of medical school applicants using qualitative tools and methods has thus become a major challenge. 299 applicants aged 18-25 formed the research group. A set of six research tools was developed in addition to the two existing ones. These included: a portfolio task, an intuitive task, a cognitive task, a personal task, an open self-efficacy questionnaire and field-notes. The criteria-based methodology design used constant comparative analysis and grounded theory techniques to produce a personal attributes profile per participant, scored on a 5-point scale holistic rubric. Qualitative validity of data gathering was checked by comparing the profiles elicited from the existing interview against the profiles elicited from the other tools, and by comparing two profiles of each of the applicants who handed in two portfolio tasks. Qualitative validity of data analysis was checked by comparing researcher results with those of an external rater (n =10). Differences between aggregated profile groups were checked by the Npar Wilcoxon Signed Ranks Test and by Spearman Rank Order Correlation Test. All subjects gave written informed consent to their participation. Privacy was protected by using code numbers. A concept map of 12 personal attributes emerged, the core constructs of which were motivation, sociability and cognition. A personal profile was elicited. Inter-rater agreement was 83.3%. Differences between groups by aggregated profiles were found significant (p < .05, p < .01, p < .001).A random sample of sixth year students (n = 12) underwent the same admission procedure as the research group. Rank order was different; and arrogance was a new construct elicited in the sixth year group. This study suggests a broadening of the methodology for selecting medical school applicants. This methodology

40 CFR 158.1000 - Applicator exposure-general requirements.

Science.gov (United States)

2010-07-01

... requirements. 158.1000 Section 158.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a... and the applicator activity of concern, including formulation type, application methods and rates...

Application of EGS and ETRAN to Problems in Medical Physics and Dosimetry

CERN Document Server

Nelson, W R

1980-01-01

The author looks at a few applications of Monte Carlo programs to problems of interest in medical physics and dosimetry. In particular, two areas are considered: 1) bremsstrahlung production from medical accelerators; 2) photon dosimetry at medium to low energies. (16 refs) .

Ethics of emergent information and communication technology applications in humanitarian medical assistance.

Science.gov (United States)

Hunt, Matthew; Pringle, John; Christen, Markus; Eckenwiler, Lisa; Schwartz, Lisa; Davé, Anushree

2016-07-01

New applications of information and communication technology (ICT) are shaping the way we understand and provide humanitarian medical assistance in situations of disaster, disease outbreak or conflict. Each new crisis appears to be accompanied by advancements in humanitarian technology, leading to significant improvements in the humanitarian aid sector. However, ICTs raise ethical questions that warrant attention. Focusing on the context of humanitarian medical assistance, we review key domains of ICT innovation. We then discuss ethical challenges and uncertainties associated with the development and application of new ICTs in humanitarian medical assistance, including avoiding harm, ensuring privacy and security, responding to inequalities, demonstrating respect, protecting relationships, and addressing expectations. In doing so, we emphasize the centrality of ethics in humanitarian ICT design, application and evaluation. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

48 CFR 801.602-73 - Review requirements for scarce medical specialist contracts and contracts for health-care resources.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Review requirements for scarce medical specialist contracts and contracts for health-care resources. 801.602-73 Section 801.602... Responsibilities 801.602-73 Review requirements for scarce medical specialist contracts and contracts for health...

18 CFR 157.6 - Applications; general requirements.

Science.gov (United States)

2010-04-01

... showing the revenue responsibility for each firm rate schedule under the pipeline's currently effective... this section requires an applicant to reveal Critical Energy Infrastructure Information (CEII), as...

[Display technologies for augmented reality in medical applications].

Science.gov (United States)

Eck, Ulrich; Winkler, Alexander

2018-04-01

One of the main challenges for modern surgery is the effective use of the many available imaging modalities and diagnostic methods. Augmented reality systems can be used in the future to blend patient and planning information into the view of surgeons, which can improve the efficiency and safety of interventions. In this article we present five visualization methods to integrate augmented reality displays into medical procedures and the advantages and disadvantages are explained. Based on an extensive literature review the various existing approaches for integration of augmented reality displays into medical procedures are divided into five categories and the most important research results for each approach are presented. A large number of mixed and augmented reality solutions for medical interventions have been developed as research prototypes; however, only very few systems have been tested on patients. In order to integrate mixed and augmented reality displays into medical practice, highly specialized solutions need to be developed. Such systems must comply with the requirements with respect to accuracy, fidelity, ergonomics and seamless integration into the surgical workflow.

Radioisotopes preparation with GA Siwabessy for application in health/medical

International Nuclear Information System (INIS)

Sunarhadijoso-Soenarjo

2003-01-01

The Center for Development of Radioisotopes and Radiopharmaceuticals (CDRR) has to improve its role and potency to comply domestic demand in radioisotope preparations. The radioisotopes are used as both primary radioisotopes and labeled compounds, especially for medical diagnosis and therapy as radiopharmaceutical preparations. The implementation of capability in production of radioisotopes and radiopharmaceuticals is fully affected by the readiness of operational function of supporting facilities in regard to maintain safety system, process and personnel as well. For those reasons, activities program has been carried out with the aims of : (a). To faithful capability in production of GA Siwabessy reactor based radioisotopes, labeled compounds and radiopharmaceutical kits, (b). To optimize normal operational function of supporting facilities and utilities, and (c). To perform invention and modification of heater and temperature control units on the air handling unit (AHU) system. Some kinds of radioactive products are dominant during the year of 2002, i.e. 153 SmCl 3 , Na 2 99 MoO 4 and Na 186 ReO 4 primary radioisotopes and 153 Sm-EDTMP labeled compound. The main utilization of the products is for research and development of processing technology and medical application as diagnostic or therapeutic agent. The operational function of supporting facilities and utilities was well performed meeting the requirement of the users. Some units of the systems partially showed degradation of working performance but it did not cause trouble in security and safety of the system, process and personnel. A heater device completed with control system has been installed as a modified part of AHU system and has been tested successfully. The operation of the heater device is significantly influential to the air temperature and humidity in working area. The required air condition, e.g. 22 - 25 o C of temperature and 40 - 50 % of humidity, can be complied on the blower motor

Mobile-Based Medical Health Application - Medi-Chat App

Directory of Open Access Journals (Sweden)

Mustapha Adamu Mohammed

2017-05-01

Full Text Available The aftermath of the development and implementation of the Android operating system and its associated Application Programming InterfacesAPI by Google culminated in the development more mobile device-enabled applications designed for our day-to-day businesses and personal use however in recent times we are experiencing a massive revolution in the use of mobile technology in the health sectors of our economy and this revolution is termed as Mobile Health Technology MHT.This new technological breakthrough has enabled the development of powerful android applications that enabled people tract and monitor the treat of heart and kidney related diseases as well as the monitoring and evaluation certain drug prescriptions. It has also changed the way we communicate with our specialist doctors from phone text to mobile-based communication. All these interventions provided by MHT have drastically increased the efficient and effective provision of health care delivery on one side and providing a common platform for prospective patients to easily interact with health professionals for medical advice and subsequent treatment of their diseases. Moreover In Ghana It would provide a much efficient and cost effective way of improving health-care methodologies in this 21st century which is characterized by information and communication technology. In this paper the main goal is to develop a mobile health application that provides common platform prospective patients and specialist doctors give free consultation and health tips on health related conditions thereby reducing the difficulty and challenges uncounted in accessing free medical health care at the already overburdened hospitals polyclinics and health centers in Ghana.

21 CFR 515.21 - Refusal to approve a medicated feed mill license application.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Refusal to approve a medicated feed mill license... SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Administrative Actions on Licenses § 515.21 Refusal to approve a medicated feed mill license application. (a) The...

42. Science week: Laser Science and applications, Aleppo (SY), 2-4 Nov 2002, Book two: Laser science and medical laser applications

International Nuclear Information System (INIS)

2005-01-01

This publication includes the papers presented at the 42nd science week of the Supreme Council of Sciences, held in Aleppo (Syria) from 2-4 November 2002. This proceedings is published in three books covering laser science and applications and in particular on material studies and medical uses. Part two covers medical applications, Part three on applications of laser in material sciences, while Part one is for contents and the proceedings program

Multimedia applications in nursing curriculum: the process of producing streaming videos for medication administration skills.

Science.gov (United States)

Sowan, Azizeh K

2014-07-01

Streaming videos (SVs) are commonly used multimedia applications in clinical health education. However, there are several negative aspects related to the production and delivery of SVs. Only a few published studies have included sufficient descriptions of the videos and the production process and design innovations. This paper describes the production of innovative SVs for medication administration skills for undergraduate nursing students at a public university in Jordan and focuses on the ethical and cultural issues in producing this type of learning resource. The curriculum development committee approved the modification of educational techniques for medication administration procedures to include SVs within an interactive web-based learning environment. The production process of the videos adhered to established principles for "protecting patients' rights when filming and recording" and included: preproduction, production and postproduction phases. Medication administration skills were videotaped in a skills laboratory where they are usually taught to students and also in a hospital setting with real patients. The lab videos included critical points and Do's and Don'ts and the hospital videos fostered real-world practices. The range of time of the videos was reasonable to eliminate technical difficulty in access. Eight SVs were produced that covered different types of the medication administration skills. The production of SVs required the collaborative efforts of experts in IT, multimedia, nursing and informatics educators, and nursing care providers. Results showed that the videos were well-perceived by students, and the instructors who taught the course. The process of producing the videos in this project can be used as a valuable framework for schools considering utilizing multimedia applications in teaching. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Integrated Medical Model Project - Overview and Summary of Historical Application

Science.gov (United States)

Myers, J.; Boley, L.; Butler, D.; Foy, M.; Goodenow, D.; Griffin, D.; Keenan, A.; Kerstman, E.; Melton, S.; McGuire, K.;

20 CFR 10.332 - What additional medical information will OWCP require to support continuing payment of benefits?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What additional medical information will OWCP require to support continuing payment of benefits? 10.332 Section 10.332 Employees' Benefits OFFICE OF... COMPENSATION UNDER THE FEDERAL EMPLOYEES' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical...

47 CFR 22.939 - Site availability requirements for applications competing with cellular renewal applications.

Science.gov (United States)

2010-10-01

... competing with cellular renewal applications. 22.939 Section 22.939 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PUBLIC MOBILE SERVICES Cellular Radiotelephone Service § 22.939 Site availability requirements for applications competing with cellular renewal applications. In...

[Mobile phone-computer wireless interactive graphics transmission technology and its medical application].

Science.gov (United States)

Huang, Shuo; Liu, Jing

2010-05-01

Application of clinical digital medical imaging has raised many tough issues to tackle, such as data storage, management, and information sharing. Here we investigated a mobile phone based medical image management system which is capable of achieving personal medical imaging information storage, management and comprehensive health information analysis. The technologies related to the management system spanning the wireless transmission technology, the technical capabilities of phone in mobile health care and management of mobile medical database were discussed. Taking medical infrared images transmission between phone and computer as an example, the working principle of the present system was demonstrated.

The application of wiki technology in medical education.

Science.gov (United States)

Rasmussen, Andrew; Lewis, Melanie; White, Jonathan

2013-01-01

BACKGROUND, AIMS AND METHODS: Recent years have seen the introduction of web-based technologies such as the 'wiki', which is a webpage whose content can be edited in real time using a web browser. This article reviews the current state of knowledge about the use of wikis in education, and considers whether wiki technology has features that might prove useful in medical education. Advantages and challenges of the technology are discussed, and recommendations for use are provided. We believe that wiki technology offers a number of potential benefits for administrators, students and instructors, including the ability to share information online, to construct knowledge together, to facilitate collaboration and to enable social learning and peer feedback. We believe that with proper planning and instructional design, wiki technology can be usefully employed in medical education. We intend to continue to study the impact of wiki technology in our own programme, and we encourage others to evaluate the application of wiki technology in other areas of medical education.

Portable mini gamma camera for medical applications

CERN Document Server

Porras, E; Benlloch, J M; El-Djalil-Kadi-Hanifi, M; López, S; Pavon, N; Ruiz, J A; Sánchez, F; Sebastiá, A

2002-01-01

A small, portable and low-cost gamma camera for medical applications has been developed and clinically tested. This camera, based on a scintillator crystal and a Position Sensitive Photo-Multiplier Tube, has a useful field of view of 4.6 cm diameter and provides 2.2 mm of intrinsic spatial resolution. Its mobility and light weight allow to reach the patient from any desired direction. This camera images small organs with high efficiency and so addresses the demand for devices of specific clinical applications. In this paper, we present the camera and briefly describe the procedures that have led us to choose its configuration and the image reconstruction method. The clinical tests and diagnostic capability are also presented and discussed.

Application Reuse Library for Software, Requirements, and Guidelines

Science.gov (United States)

Malin, Jane T.; Thronesbery, Carroll

1994-01-01

Better designs are needed for expert systems and other operations automation software, for more reliable, usable and effective human support. A prototype computer-aided Application Reuse Library shows feasibility of supporting concurrent development and improvement of advanced software by users, analysts, software developers, and human-computer interaction experts. Such a library expedites development of quality software, by providing working, documented examples, which support understanding, modification and reuse of requirements as well as code. It explicitly documents and implicitly embodies design guidelines, standards and conventions. The Application Reuse Library provides application modules with Demo-and-Tester elements. Developers and users can evaluate applicability of a library module and test modifications, by running it interactively. Sub-modules provide application code and displays and controls. The library supports software modification and reuse, by providing alternative versions of application and display functionality. Information about human support and display requirements is provided, so that modifications will conform to guidelines. The library supports entry of new application modules from developers throughout an organization. Example library modules include a timer, some buttons and special fonts, and a real-time data interface program. The library prototype is implemented in the object-oriented G2 environment for developing real-time expert systems.

Radiation protection and dosimetry issues in the medical applications of ionizing radiation

International Nuclear Information System (INIS)

Vaz, Pedro

2014-01-01

The technological advances that occurred during the last few decades paved the way to the dissemination of CT-based procedures in radiology, to an increasing number of procedures in interventional radiology and cardiology as well as to new techniques and hybrid modalities in nuclear medicine and in radiotherapy. These technological advances encompass the exposure of patients and medical staff to unprecedentedly high dose values that are a cause for concern due to the potential detrimental effects of ionizing radiation to the human health. As a consequence, new issues and challenges in radiological protection and dosimetry in the medical applications of ionizing radiation have emerged. The scientific knowledge of the radiosensitivity of individuals as a function of age, gender and other factors has also contributed to raising the awareness of scientists, medical staff, regulators, decision makers and other stakeholders (including the patients and the public) for the need to correctly and accurately assess the radiation induced long-term health effects after medical exposure. Pediatric exposures and their late effects became a cause of great concern. The scientific communities of experts involved in the study of the biological effects of ionizing radiation have made a strong case about the need to undertake low dose radiation research and the International System of Radiological Protection is being challenged to address and incorporate issues such as the individual sensitivities, the shape of dose–response relationship and tissue sensitivity for cancer and non-cancer effects. Some of the answers to the radiation protection and dosimetry issues and challenges in the medical applications of ionizing radiation lie in computational studies using Monte Carlo or hybrid methods to model and simulate particle transport in the organs and tissues of the human body. The development of sophisticated Monte Carlo computer programs and voxel phantoms paves the way to an accurate

Near field communications technology and the potential to reduce medication errors through multidisciplinary application

LENUS (Irish Health Repository)

O’Connell, Emer

2016-07-01

Patient safety requires optimal management of medications. Electronic systems are encouraged to reduce medication errors. Near field communications (NFC) is an emerging technology that may be used to develop novel medication management systems.

The role of electromagnetic separators in the production of radiotracers for bio-medical research and nuclear medical application

CERN Document Server

Beyer, Gerd-Jürgen

2003-01-01

With the growing complexity of positron emission tomography/single photon emission computed tomography imaging and the new developments in systemic radionuclide therapy there is a growing need for radioisotope preparations with higher radiochemical and radionuclidic purity that has not been achievable before. Especially important for the new applications is the specific activity of the radiotracer. Conventional methods in medical isotope production have reached their technical limitations. The role of isotope separators is discussed with examples of typical production and characterization experiments conducted at the ISOLDE and TRIUMF facilities. These preliminary experiments indicate that isotope separators have a definite role to play in the future for the production of radioisotopes for biomedical research and medical application.

Potential refractory alloy requirements for space nuclear power applications

International Nuclear Information System (INIS)

Cooper, R.H. Jr.

1984-01-01

In reviewing design requirements for refractory alloys for space nuclear applications, several key points are identified. First, the successful utilization of refractory alloys is considered an enabling requirement for the successful deployment of high efficiency, lightweight, and small space nuclear systems. Second, the recapture of refractory alloy nuclear technology developed in the 1960s and early 1970s appears to be a pacing activity in the successful utilization of refractory alloys. Third, the successful application of refractory alloys for space nuclear applications will present a significant challenge to both the materials and the systems design communities

Organic transistors with high thermal stability for medical applications.

Science.gov (United States)

Kuribara, Kazunori; Wang, He; Uchiyama, Naoya; Fukuda, Kenjiro; Yokota, Tomoyuki; Zschieschang, Ute; Jaye, Cherno; Fischer, Daniel; Klauk, Hagen; Yamamoto, Tatsuya; Takimiya, Kazuo; Ikeda, Masaaki; Kuwabara, Hirokazu; Sekitani, Tsuyoshi; Loo, Yueh-Lin; Someya, Takao

2012-03-06

The excellent mechanical flexibility of organic electronic devices is expected to open up a range of new application opportunities in electronics, such as flexible displays, robotic sensors, and biological and medical electronic applications. However, one of the major remaining issues for organic devices is their instability, especially their thermal instability, because low melting temperatures and large thermal expansion coefficients of organic materials cause thermal degradation. Here we demonstrate the fabrication of flexible thin-film transistors with excellent thermal stability and their viability for biomedical sterilization processes. The organic thin-film transistors comprise a high-mobility organic semiconductor, dinaphtho[2,3-b:2',3'-f]thieno[3,2-b]thiophene, and thin gate dielectrics comprising a 2-nm-thick self-assembled monolayer and a 4-nm-thick aluminium oxide layer. The transistors exhibit a mobility of 1.2 cm(2) V(-1)s(-1) within a 2 V operation and are stable even after exposure to conditions typically used for medical sterilization.

Image-based electronic patient records for secured collaborative medical applications.

Science.gov (United States)

Zhang, Jianguo; Sun, Jianyong; Yang, Yuanyuan; Liang, Chenwen; Yao, Yihong; Cai, Weihua; Jin, Jin; Zhang, Guozhen; Sun, Kun

2005-01-01

We developed a Web-based system to interactively display image-based electronic patient records (EPR) for secured intranet and Internet collaborative medical applications. The system consists of four major components: EPR DICOM gateway (EPR-GW), Image-based EPR repository server (EPR-Server), Web Server and EPR DICOM viewer (EPR-Viewer). In the EPR-GW and EPR-Viewer, the security modules of Digital Signature and Authentication are integrated to perform the security processing on the EPR data with integrity and authenticity. The privacy of EPR in data communication and exchanging is provided by SSL/TLS-based secure communication. This presentation gave a new approach to create and manage image-based EPR from actual patient records, and also presented a way to use Web technology and DICOM standard to build an open architecture for collaborative medical applications.

40 CFR 60.4122 - Information requirements for Hg budget permit applications.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Information requirements for Hg budget... requirements for Hg budget permit applications. A complete Hg Budget permit application shall include the following elements concerning the Hg Budget source for which the application is submitted, in a format...

38 CFR 61.42 - Threshold requirements for special needs grant applications.

Science.gov (United States)

2010-07-01

... for special needs grant applications. 61.42 Section 61.42 Pensions, Bonuses, and Veterans' Relief... requirements for special needs grant applications. To be eligible for a special needs grant, an applicant must... requirements of this part, to maintain eligibility for special need payments and has demonstrated the capacity...

[Medical school admission test at the University of Goettingen - which applicants will benefit?].

Science.gov (United States)

Simmenroth-Nayda, Anne; Meskauskas, Erik; Burckhardt, Gerhard; Görlich, Yvonne

2014-01-01

Medical schools in Germany may select 60% of the student applicants through their own admission tests. The influence of the school-leaving examination grades (EGs) in each of the procedural steps is controversial. At Goettingen Medical School, we combine a structured interview and a communicative skills assessment. We analysed how many applicants succeeded in our admission test, compared to a model which only takes EGs into account. Admission scores were transferred into SPSS-21. Sociodemographic data were submitted by the Stiftung Hochschulstart. Besides descriptive statistics, we used Pearson-correlation and means comparisons (t-test, analysis of variance). 221 applicants (EGs 1.0-1.9) were invited in the winter semester 2013/14 and 222 applicants (EGs 1.1-1.8) in the summer semester 2014. The proportion of women was 68% (winter) and 74% (summer). Sixteen and 37 applicants had a medical vocational training and performed slightly better. The analysis showed that our test was gender neutral. EGs did not correlate with interviews or skills assessment. Despite a two-fold impact of EGs, 26 (winter) and 44 (summer) of the overall 181 applicants had EGs of 1.4 -1.9, which would have been too low for admission otherwise. If EGs were only considered once, 40 (winter) and 59 (summer) applicants would have succeeded. Copyright © 2014. Published by Elsevier GmbH.

Design of a compact synchrotron light source for medical applications at NIRS

International Nuclear Information System (INIS)

Torikoshi, M.; Endo, M.; Kumada, M.; Noda, K.; Yamada, S.; Kawachi, K.

1998-01-01

A synchrotron light source dedicated to medical applications is required to be compact for installation in limited spaces at hospitals. The NIRS storage ring, with a circumference of 44.8 m, is designed to accelerate electrons up to 1.8 GeV and to store a beam of 400 mA. The ring is composed of superconducting bending magnets for downsizing. A beam of 300 MeV is injected into the ring from a microtron operated at an L-band RF frequency. There are two superconducting multipole wigglers with nine poles and a maximum field of 8 T, which can produce a photon flux of about 1.4 x 10 13 photons s -1 mrad -1 (0.1% bandwidth) -1 at 33 keV used for coronary angiography

HERCA WG Medical Applications / Sub WG 'Exposure of Asymptomatic Individuals in Health Care' - 'Position Paper on Screening'

International Nuclear Information System (INIS)

Griebel, Juergen; Ebdon-Jackson, Steve

2012-05-01

Over the course of several meetings the HERCA-Working Group (WG) 'Medical Applications' has discussed the exposure of asymptomatic individuals in health care. In particular, the discussions focused on the issue of the early detection of severe diseases, by use of X-rays, for those who do not present with symptoms. An important and established example is the use of X-ray mammography to detect early breast cancer and this has traditionally been referred to as screening. An emerging application is the use of computed tomography in a range of circumstances, some of which may be better described as a separate category of medical exposure as they are neither diagnostic nor screening in the accepted sense. The discussions have indicated that it is pivotal to clearly define the relevant terms generally applied and to clearly differentiate these terms from diagnostic examinations used in health care. In this context, it is important to note, that the revision of the Euratom Basic Safety Standards (Euratom BSS) Directive is under way and addresses in particular medical radiological procedures on asymptomatic individuals, intended to be performed for early detection of disease (Draft Proposal 29 September 2011 Article 54). Hereby, two types of examinations of asymptomatic individuals, (that in some cases have both been referred to as screening) are addressed: (1) exposures as part of screening programmes and (2) exposures associated with individual health assessment. On adoption, this directive will have significant implications for and a substantial impact on the work of the radiation protection authorities in Europe. In this position paper the WG 'Medical Applications' proposes a clear distinction between screening and radiological procedures as part of an individual health assessment and highlights special requirements for the latter. Finally, the impact on the work of radiation protection authorities in Europe is addressed

Scenario-based Requirements Elicitation in a Pain-teletreatment Application

NARCIS (Netherlands)

Widya, I.A.; Bults, Richard G.A.; Huis in 't Veld, M.H.A.; Vollenbroek-Hutten, Miriam Marie Rosé; Shishkov, Boris; Cordeiro, J.; Ranchordas, A.

2009-01-01

This paper proposes a way to elicit requirements in the domain of eHealth, in particular telemedicine treatment, that is in alignment with the evidence based working practice in medicine. In collaboration with ICT developers, medical professionals co-shape the intended system, which has to support

Application countermeasures of non-incineration technologies for medical waste treatment in China.

Science.gov (United States)

Chen, Yang; Ding, Qiong; Yang, Xiaoling; Peng, Zhengyou; Xu, Diandou; Feng, Qinzhong

2013-12-01

By the end of 2012, there were 272 modern, high-standard, centralized medical waste disposal facilities operating in various cities in China. Among these facilities nearly 50% are non-incineration treatment facilities, including the technologies of high temperature steam, chemical disinfection and microwave. Each of the non-incineration technologies has its advantages and disadvantages, and any single technology cannot offer a panacea because of the complexity of medical waste disposal. Although non-incineration treatment of medical waste can avoid the release of polychlorinated dibenzo-p-dioxins/dibenzofurans, it is still necessary to decide how to best meet the local waste management needs while minimizing the impact on the environment and public health. There is still a long way to go to establish the sustainable application and management mode of non-incineration technologies. Based on the analysis of typical non-incineration process, pollutant release, and the current tendency for technology application and development at home and abroad, this article recommends the application countermeasures of non-incineration technologies as the best available techniques and best environmental practices in China.

Requirements for AMLCDs in U.S. military applications

Science.gov (United States)

Hopper, Darrel G.; Desjardins, Daniel D.

1995-06-01

Flat panel displays are fast becoming a significant source of more defense for less money. Military instruments have begun to use color active matrix liquid crystal displays (AMLCDs). This is the beginning of a significant transition from electromechanical, CRT. dichroic LCD, and electroluminescent display designs to the AMLCD designs. We have the opportunity with this new technology to establish common products capable of meeting user requirements for sunlight-readable, color and grayscale capable, high-sharpness high-pixel count, flat panel displays for military applications. The Wright Laboratory is leading the development of recommended best practice, draft guidance standard, and performance specifications for this new generation, the flat panel cockpit display generation, of display modules based on requirements for U.S. military aircraft and ground combat human system interfaces. These requirements are similar in many regards to those in both the civil aviation and automotive industries; accordingly, commonality with these civil applications is incorporated where possible, against the requirements for military combat applications. The performance requirement may be achieved by two approaches: militarization of displays made to low requirements of a large volume civil products manufacturer like Sharp or integration of displays made to high requirements by a niche market commercial vendor, like Optical Imaging Systems, Litton Systems Limited, ImageQuest Inc., and Planar Advanced Inc. teamed with Xerox PARC and Standish Industries. [Note that the niche market companies listed are commercial off-the shelf vendors, albeit for high requirement low volume customers.] Given that the performance specifications can be met for a particular military product by either approach, the choice is based on life cycle cost and a thin analysis based on initial costs alone is not acceptable as it ignores the fact that military product life cycles and procurements are 20-60 years

ER-16 regulation. Requirements for granting the permit exceptional use of medical devices in humans

International Nuclear Information System (INIS)

2015-01-01

The purpose of this regulation is to establish requirements for applying for a permit exceptional use of medical equipment in Human Beings, the procedures for the evaluation process and bestowal. This regulation is aimed at researchers and designers of medical equipment, related to or associated with National Health Service's priority programs of interest to health.

Medical applications of californium-252

International Nuclear Information System (INIS)

Oliver, G.D. Jr.

1975-01-01

Primarily, californium-252 sources have been utilized in medicine for the treatment of neoplastic lesions. For five years, a coordinated effort between several cancer research institutions and national laboratories has developed the necessary physics, radiobiology, and engineering skills to establish an evaluation program for californium. Several more years of combined effort are required before it is known whether californium therapy is as good as or better than conventional therapy with sources like radium. Recently, development of diagnostic applications of californium in medicine has received attention. Studies comparing neutron decay activation analysis versus prompt capture gamma ray analysis are in progress. A hopeful application of prompt analysis with reasonable quantities (200 μg) of californium is the elemental analysis of bone in the human body. (U.S.)

Accelerators for Medical Applications What is so Special?

CERN Document Server

Schippers, J.M.

2016-01-01

Specific requirements of accelerators for radiation therapy with protons or ions will be discussed. The focus will be on accelerator design, operational and formal aspects. We will discuss the special requirements to reach a high reliability for patient treatments as well as an accurate delivery of the dose at the correct position in the patient using modern techniques like pencil beam scanning. It will be shown that the requirements of the accelerated beam differ from those in a nuclear physics laboratory. The way of operating such a medical device requires not only operators, but also the possibility to have a safe machine operation by non accelerator specialists at different operating sites (treatment rooms). It will be shown that the organisation and role of the control/interlock system can be considered as being the most dedicated in a particle-therapy providing facility.

28 CFR 552.26 - Medical attention in use of force and application of restraints incidents.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Medical attention in use of force and application of restraints incidents. 552.26 Section 552.26 Judicial Administration BUREAU OF PRISONS... § 552.26 Medical attention in use of force and application of restraints incidents. (a) In immediate use...

[Research on the Application of Lean Management in Medical Consumables Material Logistics Management].

Science.gov (United States)

Yang, Chai; Zhang, Wei; Gu, Wei; Shen, Aizong

2016-11-01

Solve the problems of high cost, low utilization rate of resources, low medical care quality problem in medical consumables material logistics management for scientific of medical consumables management. Analysis of the problems existing in the domestic medical consumables material logistics management in hospital, based on lean management method, SPD(Supply, Processing, Distribution) for specific applications, combined HBOS(Hospital Business Operation System), HIS (Hospital Information System) system for medical consumables material management. Achieve the lean management in medical consumables material purchase, warehouse construction, push, clinical use and retrospect. Lean management in medical consumables material can effectively control the cost in logistics management, optimize the alocation of resources, liberate unnecessary time of medical staff, improve the quality of medical care. It is a scientific management method.

14 CFR 61.123 - Eligibility requirements: General.

Science.gov (United States)

2010-01-01

... must: (a) Be at least 18 years of age; (b) Be able to read, speak, write, and understand the English language. If the applicant is unable to meet one of these requirements due to medical reasons, then the... who: (1) Conducted the required ground training or reviewed the person's home study on the...

Report on Workshop 'Radiation protection of the 'consumer' of medical irradiation applications'

International Nuclear Information System (INIS)

Geus, W.W.A.A.

1989-01-01

The Main division Radioactivity and Applications of Radiation of the Dutch Department of Welfare, Public Health and Culture has organized a 'workshop' on the protection of the patient ( or consumer) in medical applications of radiation. The EG guideline of september 3rd 1984 'In behalf of assessment of fundamental measures with regard to radiation protection of persons who are examined or treated medically' and the advice of the National Council for Public Health brought out thereabout in april 1988, served as background of the contributions and discussions presented in this collection. (H.W.). Refs.; figs.; tabs

[Application Progress of Three-dimensional Laser Scanning Technology in Medical Surface Mapping].

Science.gov (United States)

Zhang, Yonghong; Hou, He; Han, Yuchuan; Wang, Ning; Zhang, Ying; Zhu, Xianfeng; Wang, Mingshi

2016-04-01

The booming three-dimensional laser scanning technology can efficiently and effectively get spatial three-dimensional coordinates of the detected object surface and reconstruct the image at high speed,high precision and large capacity of information.Non-radiation,non-contact and the ability of visualization make it increasingly popular in three-dimensional surface medical mapping.This paper reviews the applications and developments of three-dimensional laser scanning technology in medical field,especially in stomatology,plastic surgery and orthopedics.Furthermore,the paper also discusses the application prospects in the future as well as the biomedical engineering problems it would encounter with.

A review on the application of medical infrared thermal imaging in hands

Science.gov (United States)

Sousa, Elsa; Vardasca, Ricardo; Teixeira, Sérgio; Seixas, Adérito; Mendes, Joaquim; Costa-Ferreira, António

2017-09-01

Infrared Thermal (IRT) imaging is a medical imaging modality to study skin temperature in real time, providing physiological information about the underlining structures. One of the most accessible body sites to be investigated using such imaging method is the hands, which can reflect valuable information about conditions affecting the upper limbs. The aim of this review is to acquaint the successful applications of IRT in the hands with a medical scope, opening horizons for future applications based in the achieved results. A systematic literature review was performed in order to assess in which applications medical IRT imaging was applied to the hands. The literature search was conducted in the reference databases: PubMed, Scopus and ISI Web of Science, making use of keywords (hand, thermography, infrared imaging, thermal imaging) combination that were present at the title and abstract. No temporal restriction was made. As a result, 4260 articles were identified, after removal of duplicates, 3224 articles remained and from first title and abstract filtering, a total of 388 articles were considered. After application of exclusion criteria (non-availability, non-clinical applications, reviews, case studies, written in other languages than English and using liquid crystal thermography), 146 articles were considered for this review. It can be verified that thermography provides useful diagnostic and monitoring information of conditions that directly or indirectly related to hands, as well as aiding in the treatment assessment. Trends and future challenges for IRT applications on hands are provided to stimulate researchers and clinicians to explore and address them.

Discussions in symposium 'neutron dosimetry in neutron fields - from detection techniques to medical applications'

International Nuclear Information System (INIS)

Tanimura, Y.; Sato, T.; Kumada, H.; Terunuma, T.; Sakae, T.; Harano, H.; Matsumoto, T.; Suzuki, T.; Matsufuji, N.

2008-01-01

Recently the traceability system (JCSS) of neutron standard based on the Japanese law 'Measurement Act' has been instituted. In addition, importance of the neutron dose evaluation has been increasing in not only the neutron capture medical treatment but also the proton or heavy particle therapy. Against such a background, a symposium 'Neutron dosimetry in neutron fields - From detection techniques to medical applications-' was held on March 29, 2008 and recent topics on the measuring instruments and their calibration, the traceability system, the simulation technique and the medical applications were introduced. This article summarizes the key points in the discussion at the symposium. (author)

The evolution of cognitive load theory and its application to medical education

NARCIS (Netherlands)

Leppink, Jimmie; van den Heuvel, Angelique

Cognitive Load Theory (CLT) has started to find more applications in medical education research. Unfortunately, misconceptions such as lower cognitive load always being beneficial to learning and the continued use of dated concepts and methods can result in improper applications of CLT principles in

78 FR 15974 - Importer of Controlled Substances, Notice of Application; Meridian Medical Technologies

Science.gov (United States)

2013-03-13

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances, Notice of Application; Meridian Medical Technologies Pursuant to Title 21 Code of Federal Regulations 1301.34 (a), this is notice that on January 8, 2013, Meridian Medical Technologies, 2555 Hermelin Drive, St. Louis...

HTC Vive MeVisLab integration via OpenVR for medical applications.

Science.gov (United States)

Egger, Jan; Gall, Markus; Wallner, Jürgen; Boechat, Pedro; Hann, Alexander; Li, Xing; Chen, Xiaojun; Schmalstieg, Dieter

2017-01-01

Virtual Reality, an immersive technology that replicates an environment via computer-simulated reality, gets a lot of attention in the entertainment industry. However, VR has also great potential in other areas, like the medical domain, Examples are intervention planning, training and simulation. This is especially of use in medical operations, where an aesthetic outcome is important, like for facial surgeries. Alas, importing medical data into Virtual Reality devices is not necessarily trivial, in particular, when a direct connection to a proprietary application is desired. Moreover, most researcher do not build their medical applications from scratch, but rather leverage platforms like MeVisLab, MITK, OsiriX or 3D Slicer. These platforms have in common that they use libraries like ITK and VTK, and provide a convenient graphical interface. However, ITK and VTK do not support Virtual Reality directly. In this study, the usage of a Virtual Reality device for medical data under the MeVisLab platform is presented. The OpenVR library is integrated into the MeVisLab platform, allowing a direct and uncomplicated usage of the head mounted display HTC Vive inside the MeVisLab platform. Medical data coming from other MeVisLab modules can directly be connected per drag-and-drop to the Virtual Reality module, rendering the data inside the HTC Vive for immersive virtual reality inspection.

HTC Vive MeVisLab integration via OpenVR for medical applications.

Directory of Open Access Journals (Sweden)

Jan Egger

Full Text Available Virtual Reality, an immersive technology that replicates an environment via computer-simulated reality, gets a lot of attention in the entertainment industry. However, VR has also great potential in other areas, like the medical domain, Examples are intervention planning, training and simulation. This is especially of use in medical operations, where an aesthetic outcome is important, like for facial surgeries. Alas, importing medical data into Virtual Reality devices is not necessarily trivial, in particular, when a direct connection to a proprietary application is desired. Moreover, most researcher do not build their medical applications from scratch, but rather leverage platforms like MeVisLab, MITK, OsiriX or 3D Slicer. These platforms have in common that they use libraries like ITK and VTK, and provide a convenient graphical interface. However, ITK and VTK do not support Virtual Reality directly. In this study, the usage of a Virtual Reality device for medical data under the MeVisLab platform is presented. The OpenVR library is integrated into the MeVisLab platform, allowing a direct and uncomplicated usage of the head mounted display HTC Vive inside the MeVisLab platform. Medical data coming from other MeVisLab modules can directly be connected per drag-and-drop to the Virtual Reality module, rendering the data inside the HTC Vive for immersive virtual reality inspection.

The role of medical physicist in radiation protection

International Nuclear Information System (INIS)

Nusslin, F.

2010-01-01

Ionizing Radiation is applied in Radiation Therapy, Nuclear medicine and Diagnostic Radiology. Radiation Protection in Medical Application of Ionizing Radiation requires specific Professional Competence in all relevant details of the radiation source instrumentation / equipment clinical dosimetry application procedures quality assurance medical risk-benefit assessment. Application in general include Justification of practices (sufficient benefit to the exposed individuals) Limitation of doses to individuals (occupational / public exposure) Optimization of Protection (magnitude and likelihood of exposures, and the number of individuals exposed will be ALARA. Competence of persons is normally assessed by the State by having a formal mechanism for registration, accreditation or certification of medical physicists in the various specialties (e.g. diagnostic radiology, radiation therapy, nuclear medicine). The patient safety in the use of medical radiation will be increased through: Consistent education and certification of medical team members, whose qualifications are recognized nationally, and who follow consensus practice guidelines that meet established national accrediting standards

Potential medical applications of the plasma focus in the radioisotope production for PET imaging

International Nuclear Information System (INIS)

Roshan, M.V.; Razaghi, S.; Asghari, F.; Rawat, R.S.; Springham, S.V.; Lee, P.; Lee, S.; Tan, T.L.

2014-01-01

Devices other than the accelerators are desired to be investigated for generating high energy particles to induce nuclear reaction and positron emission tomography (PET) producing radioisotopes. The experimental data of plasma focus devices (PF) are studied and the activity scaling law for External Solid Target (EST) activation is established. Based on the scaling law and the techniques to enhance the radioisotopes production, the feasibility of generating the required activity for PET imaging is studied. - Highlights: • Short lived radioisotopes for PET imaging are produced in plasma focus device. • The scaling law of the activity induced with plasma focus energy is established. • The potential medical applications of plasma focus are studied

Hungarian medical physics MSc education

International Nuclear Information System (INIS)

Legrady, D.; Czifrus, Z.; Zarand, P.; Aszodi, A.; Pesznyak, C.; Major, T.

2012-01-01

The medical physics specialisation aims at providing high level interdisciplinary theoretical and practical knowledge and readily applicable skills, which can put into action in both the clinical and the R and D field. The first competence based gradual medical physics course in the B.Sc./M.Sc. system in Hungary was launched two years ago at the Faculty of Natural Sciences of Budapest University of Technology and Economics managed by the Institute of Nuclear Techniques. The MSc programme was compiled on the base of EFOMP, IPEM, AAPM and IAEA recommendations. The course curriculum comprises fundamental physical subjects (atomic and molecular physics, nuclear physics and particle physics) as well as fundamental medical knowledge (anatomy, physiology and radiobiology) required for subjects of diagnostic and therapy. Students of this MSc branch may chose further subjects from a 'compulsory optional' set of subjects, which contains medical imaging, X-ray diagnostics, radiation therapy, magnetic resonance imaging, radiation protection, Monte Carlo calculation and its clinical applications, ultrasound diagnostics and nuclear medicine. (authors)

Roles and Responsibilities, and Education and Training Requirements for Clinically Qualified Medical Physicists (Russian Edition)

International Nuclear Information System (INIS)

2014-01-01

This publication addresses the shortfall of well trained and clinically qualified medical physicists working in radiation medicine. The roles, responsibilities and clinical training requirements of medical physicists have not always been well defined or well understood by health care professionals, health authorities and regulatory agencies. To fill this gap, this publication provides recommendations for the academic education and clinical training of clinically qualified medical physicists, including recommendations for their accreditation certification and registration, along with continuous professional development. The goal is to establish criteria that support the harmonization of education and clinical training worldwide

Machine learning for epigenetics and future medical applications

OpenAIRE

Holder, Lawrence B.; Haque, M. Muksitul; Skinner, Michael K.

2017-01-01

ABSTRACT Understanding epigenetic processes holds immense promise for medical applications. Advances in Machine Learning (ML) are critical to realize this promise. Previous studies used epigenetic data sets associated with the germline transmission of epigenetic transgenerational inheritance of disease and novel ML approaches to predict genome-wide locations of critical epimutations. A combination of Active Learning (ACL) and Imbalanced Class Learning (ICL) was used to address past problems w...

14 CFR 61.153 - Eligibility requirements: General.

Science.gov (United States)

2010-01-01

... the English language. If the applicant is unable to meet one of these requirements due to medical... rating issued under this part; (2) Meet the military experience requirements under § 61.73 of this part... military pilot or former rated military pilot of an Armed Force of the United States; or (3) Holds either a...

Liquid Marbles: From Industrial to Medical Applications

Directory of Open Access Journals (Sweden)

Roxana-Elena Avrămescu

2018-05-01

Full Text Available Liquid marbles are versatile structures demonstrating a pseudo-Leidenfrost wetting regime formed by encapsulating microscale volumes of liquid in a particle shell. The liquid core is completely separated from the exterior through air pockets. The external phase consists of hydrophobic particles, in most cases, or hydrophilic ones distributed as aggregates. Their interesting features arise from the double solid-fluid character. Thus, these interesting formations, also known as “dry waters”, have gained attention in surface science. This review paper summarizes a series of proposed formulations, fabrication techniques and properties, in correlation with already discovered and emerging applications. A short general review of the surface properties of powders (contact angle, superficial tension is proposed, followed by a presentation of liquid marbles’ properties (superficial characteristics, elasticity, self-propulsion etc.. Finally, applications of liquid marbles are discussed, mainly as helpful and yet to be exploited structures in the pharmaceutical and medical field. Innovative pharmaceutical forms (Pickering emulsions are also means of use taken into account as applications which need further investigation.

Dissemination of medical applications of nuclear energy with virtual reality technology

International Nuclear Information System (INIS)

Botelho, Felipe M.; Oliveira, Beatriz A.R.

2007-01-01

This work makes use of Virtual Reality technology to disseminate medical applications of nuclear energy, with educational purposes. Virtual Reality is an effective learning tool, since navigation and interaction in virtual worlds can improve motivation in the learning process. With this technology, learning can be achieved in a clearer, joyful and more objective way. Among the existing medical applications of nuclear energy, this work focuses on the use of radiopharmaceuticals. The goal is to simulate this application in a virtual environment, for educational purposes, and to show the absorption of a radiopharmaceutical by the human body, during a diagnostics or treatment procedure. An example has been chosen, for Iodine radiopharmaceutical, which has affinity with the thyroid, and then concentrates in this organ. During the simulation, the concentration of the radioactive Iodine in the thyroid can be emphasized, and in the sequence, the virtual patient can be shown during the imaging procedure. (author)

A qualitative analysis of statements on motivation of applicants for medical school.

Science.gov (United States)

Wouters, Anouk; Bakker, Anneke H; van Wijk, Inge J; Croiset, Gerda; Kusurkar, Rashmi A

2014-09-23

Selection committees try to ascertain that motivated students are selected for medical school. Self-determination theory stresses that the type of motivation is more important than the quantity of motivation. Autonomous motivation, compared to controlled motivation, in students leads to better learning outcomes. Applicants can express their motivation in written statements, a selection tool which has been found to elicit heterogeneous responses, hampering the comparison of applicants. This study investigates the content of applicants' statements on motivation for medical school in particular, the possibility to distinguish the type of motivation and the differences between selected and non-selected applicants. A thematic analysis was conducted on written statements on motivation (n = 96), collected as a part of the selection procedure for the graduate entry program for medicine and research at our institution. Themes were identified as motivation-related and motivation-unrelated (additional). The motivation-related themes were further classified as autonomous and controlled types of motivation. Group percentages for each theme were compared between selected and non-selected applicants using Chi-square test and Fisher exact test. Applicants mainly described reasons belonging to autonomous type of motivation and fewer reasons belonging to controlled type of motivation. Additional themes in the statements included previous work experience and academic qualifications, ambitions, expectations and descriptions of the program and profession, personal qualities, and personal history. Applicants used strong words to support their stories. The selected and non-selected applicants did not differ in their types of motivation. Non-selected applicants provided more descriptions of personal history than selected applicants (p motivation does not appear to distinguish between applicants in selection for medical school. Both selected and non-selected applicants reported

77 FR 19716 - Importer of Controlled Substances; Notice of Application Meridian Medical Technologies

Science.gov (United States)

2012-04-02

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Application Meridian Medical Technologies Pursuant to 21 U.S.C. 958(i), the Attorney General shall, prior to... is notice that on January 4, 2012, Meridian Medical Technologies, 2555 Hermelin Drive, St. Louis...

Cross-Cutting public policy requirements applicable to federal grants

Science.gov (United States)

There are cross-cutting public policy requirements applicable to Federal grants, including those awarded by the EPA. Some of those requirements are included here because they have been part of appropriations acts for several years without change.

Energy minimization in medical image analysis: Methodologies and applications.

Science.gov (United States)

Zhao, Feng; Xie, Xianghua

2016-02-01

Energy minimization is of particular interest in medical image analysis. In the past two decades, a variety of optimization schemes have been developed. In this paper, we present a comprehensive survey of the state-of-the-art optimization approaches. These algorithms are mainly classified into two categories: continuous method and discrete method. The former includes Newton-Raphson method, gradient descent method, conjugate gradient method, proximal gradient method, coordinate descent method, and genetic algorithm-based method, while the latter covers graph cuts method, belief propagation method, tree-reweighted message passing method, linear programming method, maximum margin learning method, simulated annealing method, and iterated conditional modes method. We also discuss the minimal surface method, primal-dual method, and the multi-objective optimization method. In addition, we review several comparative studies that evaluate the performance of different minimization techniques in terms of accuracy, efficiency, or complexity. These optimization techniques are widely used in many medical applications, for example, image segmentation, registration, reconstruction, motion tracking, and compressed sensing. We thus give an overview on those applications as well. Copyright © 2015 John Wiley & Sons, Ltd.

Failure modes and effects criticality analysis and accelerated life testing of LEDs for medical applications

Science.gov (United States)

Sawant, M.; Christou, A.

2012-12-01

While use of LEDs in Fiber Optics and lighting applications is common, their use in medical diagnostic applications is not very extensive. Since the precise value of light intensity will be used to interpret patient results, understanding failure modes [1-4] is very important. We used the Failure Modes and Effects Criticality Analysis (FMECA) tool to identify the critical failure modes of the LEDs. FMECA involves identification of various failure modes, their effects on the system (LED optical output in this context), their frequency of occurrence, severity and the criticality of the failure modes. The competing failure modes/mechanisms were degradation of: active layer (where electron-hole recombination occurs to emit light), electrodes (provides electrical contact to the semiconductor chip), Indium Tin Oxide (ITO) surface layer (used to improve current spreading and light extraction), plastic encapsulation (protective polymer layer) and packaging failures (bond wires, heat sink separation). A FMECA table is constructed and the criticality is calculated by estimating the failure effect probability (β), failure mode ratio (α), failure rate (λ) and the operating time. Once the critical failure modes were identified, the next steps were generation of prior time to failure distribution and comparing with our accelerated life test data. To generate the prior distributions, data and results from previous investigations were utilized [5-33] where reliability test results of similar LEDs were reported. From the graphs or tabular data, we extracted the time required for the optical power output to reach 80% of its initial value. This is our failure criterion for the medical diagnostic application. Analysis of published data for different LED materials (AlGaInP, GaN, AlGaAs), the Semiconductor Structures (DH, MQW) and the mode of testing (DC, Pulsed) was carried out. The data was categorized according to the materials system and LED structure such as AlGaInP-DH-DC, Al

Rough-fuzzy pattern recognition applications in bioinformatics and medical imaging

CERN Document Server

Maji, Pradipta

2012-01-01

Learn how to apply rough-fuzzy computing techniques to solve problems in bioinformatics and medical image processing Emphasizing applications in bioinformatics and medical image processing, this text offers a clear framework that enables readers to take advantage of the latest rough-fuzzy computing techniques to build working pattern recognition models. The authors explain step by step how to integrate rough sets with fuzzy sets in order to best manage the uncertainties in mining large data sets. Chapters are logically organized according to the major phases of pattern recognition systems dev

HTGR Industrial Application Functional and Operational Requirements

International Nuclear Information System (INIS)

Demick, L.E.

2010-01-01

This document specifies the functional and performance requirements to be used in the development of the conceptual design of a high temperature gas-cooled reactor (HTGR) based plant supplying energy to a typical industrial facility. These requirements were developed from collaboration with industry and HTGR suppliers over the preceding three years to identify the energy needs of industrial processes for which the HTGR technology is technically and economically viable. The functional and performance requirements specified herein are an effective representation of the industrial sector energy needs and an effective basis for developing a conceptual design of the plant that will serve the broadest range of industrial applications.

78 FR 43820 - Medicare Program; Medical Loss Ratio Requirements for the Medicare Advantage and the Medicare...

Science.gov (United States)

2013-07-22

... and 423 [CMS-4173-CN] RIN 0938-AR69 Medicare Program; Medical Loss Ratio Requirements for the Medicare... number of technical, typographical, and cross-referencing errors that are identified and corrected in the... Minimum Medical Loss Ratio, we made a typographical error in a section number. On page 31311, in Sec. 423...

Medical application and its promotion of X-band linacs

International Nuclear Information System (INIS)

Uesaka, Mitsuru; Dobashi, Katsuhiro; Kaneyasu, Tatsuo

2005-01-01

This article presents the current status of the development of the monochromatic tunable hard X-ray source by the X-band linac and YAG leasers. New medical applications such as 2 colors CT and Drug Delivery System (DDS) are planned. Finally, the virtual laboratory for the distribution of the system to the society is discussed. (author)

10 CFR 430.52 - Requirements for applications.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Requirements for applications. 430.52 Section 430.52 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CONSERVATION PROGRAM FOR CONSUMER PRODUCTS Small... Efficiency Standards, Assistant Secretary for Conservation and Renewable Energy, Forrestal Building, 1000...

Scanning Micromirror Platform Based on MEMS Technology for Medical Application

Directory of Open Access Journals (Sweden)

Eakkachai Pengwang

2016-02-01

Full Text Available This topical review discusses recent development and trends on scanning micromirrors for biomedical applications. This also includes a biomedical micro robot for precise manipulations in a limited volume. The characteristics of medical scanning micromirror are explained in general with the fundamental of microelectromechanical systems (MEMS for fabrication processes. Along with the explanations of mechanism and design, the principle of actuation are provided for general readers. In this review, several testing methodology and examples are described based on many types of actuators, such as, electrothermal actuators, electrostatic actuators, electromagnetic actuators, pneumatic actuators, and shape memory alloy. Moreover, this review provides description of the key fabrication processes and common materials in order to be a basic guideline for selecting micro-actuators. With recent developments on scanning micromirrors, performances of biomedical application are enhanced for higher resolution, high accuracy, and high dexterity. With further developments on integrations and control schemes, MEMS-based scanning micromirrors would be able to achieve a better performance for medical applications due to small size, ease in microfabrication, mass production, high scanning speed, low power consumption, mechanical stable, and integration compatibility.

MediFrame: A Tablet Application to Plan, Inform, Remind and Sustain Older Adults Medication Intake

DEFF Research Database (Denmark)

Dalgaard, Lea Gulstav; Grönvall, Erik; Verdezoto, Nervo

2013-01-01

treatment or a specific condition. In this paper, we discuss experiences from designing the tablet-based application MediFrame. MediFrame is a personal medication management system to support older adults in non-clinical settings such as the home. The paper describes the user-centered design process...... and the resulting tablet application. We show how MediFrame can be used to support adherence in medical treatments through fieldwork informed use scenarios. Based on early qualitative feedback, we also discuss lessons learned and how designers can support a holistic medication experience for an older adult...

Review of Cyclotrons for the Production of Radioactive Isotopes for Medical and Industrial Applications

Science.gov (United States)

Schmor, Paul

2011-02-01

Radioactive isotopes are used in a wide range of medical, biological, environmental and industrial applications. Cyclotrons are the primary tool for producing the shorter-lived, proton-rich radioisotopes currently used in a variety of medical applications. Although the primary use of the cyclotron-produced short-lived radioisotopes is in PET/CT (positron emission tomography/computed tomography) and SPECT (single photon emission computed tomography) diagnostic medical procedures, cyclotrons are also producing longer-lived isotopes for therapeutic procedures as well as for other industrial and applied science applications. Commercial suppliers of cyclotrons are responding by providing a range of cyclotrons in the energy range of 3-70MeV for the differing needs of the various applications. These cyclotrons generally have multiple beams servicing multiple targets. This review article presents some of the applications of the radioisotopes and provides a comparison of some of the capabilities of the various current cyclotrons. The use of nuclear medicine and the number of cyclotrons supplying the needed isotopes are increasing. It is expected that there will soon be a new generation of small "tabletop" cyclotrons providing patient doses on demand.

[Design and application of medical electric leg-raising machine].

Science.gov (United States)

Liang, Jintang; Chen, Jinyuan; Zhao, Zixian; Lin, Jinfeng; Li, Juanhong; Zhong, Jingliang

2017-08-01

Passive leg raising is widely used in clinic, but it lacks of specialized mechanical raise equipment. It requires medical staff to raise leg by hand or requires a multi-functional bed to raise leg, which takes time and effort. Therefore we have developed a new medical electric leg-raising machine. The equipment has the following characteristics: simple structure, stable performance, easy operation, fast and effective, safe and comfortable. The height range of the lifter is 50-120 cm, the range of the angle of raising leg is 10degree angle-80degree angle, the maximum supporting weight is 40 kg. Because of raising the height of the lower limbs and making precise angle, this equipment can completely replace the traditional manner of lifting leg by hand with multi-functional bed to lift patients' leg and can reduce the physical exhaustion and time consumption of medical staff. It can change the settings at any time to meet the needs of the patient; can be applied to the testing of PLR and dynamically assessing the hemodynamics; can prevent deep vein thrombosis and some related complications of staying in bed; and the machine is easy to be cleaned and disinfected, which can effectively avoid hospital acquired infection and cross infection; and can also be applied to emergency rescue of various disasters and emergencies.

Application Requirements for Middleware for Mobile and Pervasive Systems

DEFF Research Database (Denmark)

Christensen, Henrik Bærbak; Raatikainen, Kimmo; Nakajim, Tatsuo

2002-01-01

In this paper, we examine the requirements for future middleware to support mobile and pervasive applications and identify key research areas. We illustrate the research areas with requirements identified in two specific research projects concerning pervasive healthcare and home entertainment....

Applications of Monte Carlo method in Medical Physics

International Nuclear Information System (INIS)

Diez Rios, A.; Labajos, M.

1989-01-01

The basic ideas of Monte Carlo techniques are presented. Random numbers and their generation by congruential methods, which underlie Monte Carlo calculations are shown. Monte Carlo techniques to solve integrals are discussed. The evaluation of a simple monodimensional integral with a known answer, by means of two different Monte Carlo approaches are discussed. The basic principles to simualate on a computer photon histories reduce variance and the current applications in Medical Physics are commented. (Author)

[Delegation of medical activities in acute pain therapy].

Science.gov (United States)

Erlenwein, J; Moroder, A; Biermann, E; Petzke, F; Ehlers, A P F; Bitter, H; Pogatzki-Zahn, E

2018-01-01

Acute pain management is an interprofessional and interdisciplinary task and requires a good and trustful cooperation between stakeholders. Despite provisions in Germany according to which medical treatment can only be rendered by a formally qualified physician ("Arztvorbehalt"), a physician does not have to carry out every medical activity in person. Under certain conditions, some medical activities can be delegated to medical auxiliary personnel but they need to be (1) instructed, (2) supervised and (3) checked by the physician himself; however, medical history, diagnostic assessment and evaluation, indications, therapy planning (e.g. selection, dosage), therapeutic decisions (e. g. modification or termination of therapy) and obtaining informed consent cannot be delegated. With respect to drug therapy, monitoring of the therapy remains the personal responsibility of the physician, while the actual application of medication can be delegated. From a legal perspective, the current practice needs to be stressed about what is within the mandatory requirements and what is not when medical activities are delegated to non-medical staff. The use of standards of care improves treatment quality but like any medical treatment it must be based on the physician's individual assessment and indications for each patient and requires personal contact between physician and patient. Delegation on the ward and in acute pain therapy requires the authorization of the delegator to give instructions in the respective setting. The transfer of non-delegable duties to non-medical personnel is regarded as medical malpractice.

Medical-Information-Management System

Science.gov (United States)

Alterescu, Sidney; Friedman, Carl A.; Frankowski, James W.

1989-01-01

Medical Information Management System (MIMS) computer program interactive, general-purpose software system for storage and retrieval of information. Offers immediate assistance where manipulation of large data bases required. User quickly and efficiently extracts, displays, and analyzes data. Used in management of medical data and handling all aspects of data related to care of patients. Other applications include management of data on occupational safety in public and private sectors, handling judicial information, systemizing purchasing and procurement systems, and analyses of cost structures of organizations. Written in Microsoft FORTRAN 77.

High-performance floating-point image computing workstation for medical applications

Science.gov (United States)

Mills, Karl S.; Wong, Gilman K.; Kim, Yongmin

1990-07-01

The medical imaging field relies increasingly on imaging and graphics techniques in diverse applications with needs similar to (or more stringent than) those of the military, industrial and scientific communities. However, most image processing and graphics systems available for use in medical imaging today are either expensive, specialized, or in most cases both. High performance imaging and graphics workstations which can provide real-time results for a number of applications, while maintaining affordability and flexibility, can facilitate the application of digital image computing techniques in many different areas. This paper describes the hardware and software architecture of a medium-cost floating-point image processing and display subsystem for the NeXT computer, and its applications as a medical imaging workstation. Medical imaging applications of the workstation include use in a Picture Archiving and Communications System (PACS), in multimodal image processing and 3-D graphics workstation for a broad range of imaging modalities, and as an electronic alternator utilizing its multiple monitor display capability and large and fast frame buffer. The subsystem provides a 2048 x 2048 x 32-bit frame buffer (16 Mbytes of image storage) and supports both 8-bit gray scale and 32-bit true color images. When used to display 8-bit gray scale images, up to four different 256-color palettes may be used for each of four 2K x 2K x 8-bit image frames. Three of these image frames can be used simultaneously to provide pixel selectable region of interest display. A 1280 x 1024 pixel screen with 1: 1 aspect ratio can be windowed into the frame buffer for display of any portion of the processed image or images. In addition, the system provides hardware support for integer zoom and an 82-color cursor. This subsystem is implemented on an add-in board occupying a single slot in the NeXT computer. Up to three boards may be added to the NeXT for multiple display capability (e

7 CFR 3560.55 - Applicant eligibility requirements.

Science.gov (United States)

2010-01-01

... Indian tribe as defined in § 3560.11; or a limited liability company (LLC), nonprofit organization, consumer cooperative, trust, partnership, or limited partnership in which the principals are U.S. citizens... for limited partnerships. In addition to the applicant eligibility requirements of paragraphs (a) and...

Synchrotrons and their applications in medical imaging and therapy

International Nuclear Information System (INIS)

Lewis, R.

2004-01-01

Full text: Australasia's first synchrotron is being built on the campus of Monash University near Melbourne. Is it of any relevance to the medical imaging and radiation therapy communities? The answer is an unequivocal yes. Synchrotrons overcome many of the problems with conventional X-ray sources and as a result make it possible to demonstrate extraordinary advances in both X-ray imaging and indeed in radio-therapy. Synchrotron imaging offers us a window into what is possible and the results are spectacular. Specific examples include lung images that reveal alveolar structure and computed tomography of single cells. For therapy treatments are being pioneered that seem to be effective on high grade gliomas. An overview of the status of medical applications using synchrotrons will be given and the proposed Australian medical imaging and therapy facilities will be described and some of the proposed research highlighted. Copyright (2004) Australasian College of Physical Scientists and Engineers in Medicine

Applying open source data visualization tools to standard based medical data.

Science.gov (United States)

Kopanitsa, Georgy; Taranik, Maxim

2014-01-01

Presentation of medical data in personal health records (PHRs) requires flexible platform independent tools to ensure easy access to the information. Different backgrounds of the patients, especially elder people require simple graphical presentation of the data. Data in PHRs can be collected from heterogeneous sources. Application of standard based medical data allows development of generic visualization methods. Focusing on the deployment of Open Source Tools, in this paper we applied Java Script libraries to create data presentations for standard based medical data.

Metadata requirements for results of diagnostic imaging procedures: a BIIF profile to support user applications

Science.gov (United States)

Brown, Nicholas J.; Lloyd, David S.; Reynolds, Melvin I.; Plummer, David L.

2002-05-01

A visible digital image is rendered from a set of digital image data. Medical digital image data can be stored as either: (a) pre-rendered format, corresponding to a photographic print, or (b) un-rendered format, corresponding to a photographic negative. The appropriate image data storage format and associated header data (metadata) required by a user of the results of a diagnostic procedure recorded electronically depends on the task(s) to be performed. The DICOM standard provides a rich set of metadata that supports the needs of complex applications. Many end user applications, such as simple report text viewing and display of a selected image, are not so demanding and generic image formats such as JPEG are sometimes used. However, these are lacking some basic identification requirements. In this paper we make specific proposals for minimal extensions to generic image metadata of value in various domains, which enable safe use in the case of two simple healthcare end user scenarios: (a) viewing of text and a selected JPEG image activated by a hyperlink and (b) viewing of one or more JPEG images together with superimposed text and graphics annotation using a file specified by a profile of the ISO/IEC Basic Image Interchange Format (BIIF).

21 CFR 515.25 - Revocation of order refusing to approve a medicated feed mill license application or suspending...

Science.gov (United States)

2010-04-01

... medicated feed mill license application or suspending or revoking a license. 515.25 Section 515.25 Food and..., FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Administrative Actions on Licenses § 515.25 Revocation of order refusing to approve a medicated feed mill license application or suspending or revoking a...

Supporting medical education research quality: the Association of American Medical Colleges' Medical Education Research Certificate program.

Science.gov (United States)

Gruppen, Larry D; Yoder, Ernie; Frye, Ann; Perkowski, Linda C; Mavis, Brian

2011-01-01

The quality of the medical education research (MER) reported in the literature has been frequently criticized. Numerous reasons have been provided for these shortcomings, including the level of research training and experience of many medical school faculty. The faculty development required to improve MER can take various forms. This article describes the Medical Education Research Certificate (MERC) program, a national faculty development program that focuses exclusively on MER. Sponsored by the Association of American Medical Colleges and led by a committee of established medical education researchers from across the United States, the MERC program is built on a set of 11 interactive workshops offered at various times and places across the United States. MERC participants can customize the program by selecting six workshops from this set to fulfill requirements for certification. This article describes the history, operations, current organization, and evaluation of the program. Key elements of the program's success include alignment of program content and focus with needs identified by prospective users, flexibility in program organization and logistics to fit participant schedules, an emphasis on practical application of MER principles in the context of the participants' activities and interests, consistency in program content and format to ensure standards of quality, and a sustainable financial model. The relationship between the national MERC program and local faculty development initiatives is also described. The success of the MERC program suggests that it may be a possible model for nationally disseminated faculty development programs in other domains.

Classification and evaluation of medical devices

Directory of Open Access Journals (Sweden)

Edina Vranić

2003-05-01

Full Text Available Medical devices and medical disposables contribute significantly to the quality and effectiveness of the health care system. It is necessary to commit scientifically sound regulatory environment that will provide consumers with the best medical care. This includes continued services to small manufacturers, readily available guidance on FDA requirements, predictable and reasonable response times on applications for marketing, and equitable enforcement. But in the public interest, this commitment to the industry must be coupled with a reciprocal commitment: that medical device firms will meet high standards in the design, manufacture, and evaluation of their products. The protections afforded our consumer, and the benefits provided the medical device industry, cannot be underestimated.

10 CFR 451.8 - Application content requirements.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Application content requirements. 451.8 Section 451.8 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.8... metered net electric energy generated and sold during the prior fiscal year by the qualified renewable...

Clinical Requirements in the Implementation of the European Medical Exposure Directive

International Nuclear Information System (INIS)

Ringertz, H.

2000-01-01

The requirements of Directive 97/43/EURATOM are specific and explicit. There are significant resource implications at hospital, academic and state levels in order to comply with the Directive. At hospital level, implications for rapid patient throughput as is currently required need to be addressed. A key element in improving radiation protection at hospital level is a properly constituted and functioning Radiation Safety Committee including members from departments involved in the use of ionising radiation. It should promote quality assurance programmes and receive reports and may also be responsible for audit of radiation procedures and outcomes. The primary objective should be to put satisfactory arrangements in place at local and national level. This will prove challenging in the time scale provided given the rigorous requirements of the Directives. Harmonisation of radiation protection arrangements across Europe is a long-term ambition as diversity of medical, legal and social legislation within the EU is considerable. (author)

Application of a latent variables model for the medical images analysis

International Nuclear Information System (INIS)

Campos S, Y.; Ruiz C, S.

2008-01-01

In recent years the technological advance has allowed the significant advance in diverse research fields, the medicine has not been exempt of this technology and the use of this technology has allowed a significant advance in the equipment that are used to obtain medical images. The quantity of information that is generated with this equipment has grown in exponential form and it is a difficult task to carry out a quantitative analysis of the data also the manipulation of big quantities of information makes the medical images analysis a complicated task. It is in fact this complexity what motivates this work where one of the main objectives is the analysis of techniques that allow to work with the complexity of the data generated with medical equipment. Likewise, it is wanted to illustrate an application of the peaceful uses of the nuclear energy to treat a medical problem where the diagnostic it depends essentially on the current medical equipment to give an appropriate treatment to the patients. (Author)

Using Contemporary Leadership Skills in Medication Safety Programs.

Science.gov (United States)

Hertig, John B; Hultgren, Kyle E; Weber, Robert J

2016-04-01

The discipline of studying medication errors and implementing medication safety programs in hospitals dates to the 1970s. These initial programs to prevent errors focused only on pharmacy operation changes - and not the broad medication use system. In the late 1990s, research showed that faulty systems, and not faulty people, are responsible for errors and require a multidisciplinary approach. The 2013 ASHP Statement on the Role of the Medication Safety Leader recommended that medication safety leaders be integrated team members rather than a single point of contact. Successful medication safety programs must employ a new approach - one that embraces the skills of all health care team members and positions many leaders to improve safety. This approach requires a new set of leadership skills based on contemporary management principles, including followership, team-building, tracking and assessing progress, storytelling and communication, and cultivating innovation, all of which promote transformational change. The application of these skills in developing or changing a medication safety program is reviewed in this article.

Fiber optic temperature sensors for medical applications

Science.gov (United States)

Schaafsma, David T.; Palmer, Gail; Bechtel, James H.

2003-07-01

Recent developments in fiber-optic sensor technology have demonstrated the utility of fiber-optic sensors for both medical and industrial applications. Fiber sensors based on fluorescent decay of rare earth doped materials allow rapid and accurate temperature measurement in challenging environments. Here we review the principles of operation of these sensors with a rare earth doped probe material and demonstrate why this material is an excellent choice for these types of sensors. The decay time technique allows accurate temperature determination from two measurements of the fluorescence intensity at a well-defined time interval. With this method, all instrumental and extraneous environmental effect will cancel, thus providing an accurate temperature measurement. Stability data will be presented for the fiber-optic probes. For medical applications, new breakthroughs in RF ablation technology and electro-surgical procedures are being introduced as alternative, less invasive treatment for removal of small tumors and for removal of plaque within arteries as a preventive treatment that avoids open heart surgery. The availability of small diameter temperature probes (230 microns or 450 microns in diameter) offers a whole new scope to temperature measurement. Accurate and reliable temperature monitoring during any laser treatment procedure or RF ablation at the surgical site is critical. Precise, NIST traceable reliable results are needed to prevent overheating or underheating during treatment. In addition, how interventional catheters are used in hyperthermia studies and the advantages to having flexible cables and multiple sensors are discussed. Preliminary data is given from an animal study where temperature was monitored in a pig during an RF study.

20 CFR 655.130 - Application filing requirements.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Application filing requirements. 655.130 Section 655.130 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY... Certification must be mailed, and will also post these addresses on the OFLC Internet Web site at http://www...

Roles and Responsibilities, and Education and Training Requirements for Clinically Qualified Medical Physicists

International Nuclear Information System (INIS)

2013-01-01

The IAEA technical cooperation project Strengthening Medical Physics in Radiation Medicine was approved by the IAEA Board of Governors for the period 2009-2013 with the aim of ensuring the safe and effective diagnosis and treatment of patients. The IAEA, together with the World Health Organization and stakeholders from numerous medical physics professional societies worldwide, including the International Organization for Medical Physics (IOMP), the European Federation of Organisations for Medical Physics, the American Association of Physicists in Medicine (AAPM), the Latin American Medical Physics Association, the Asia-Oceania Federation of Organizations for Medical Physics, the European Society for Radiotherapy and Oncology, the European Commission and the International Radiation Protection Association, as well as regional counterparts from Africa, Asia, Europe and Latin America, met in Vienna in May 2009 to plan and coordinate the new project. A shortage of clinically qualified medical physicists (CQMPs), insufficient education and training (especially properly organized and coordinated clinical training), and lack of professional recognition were identified as the main problems to be addressed under this project. This publication was developed under the project framework in response to these findings. It aims, first, at defining appropriately and unequivocally the roles and responsibilities of a CQMP in specialties of medical physics related to the use of ionizing radiation, such as radiation therapy, nuclear medicine, and diagnostic and interventional radiology. Important, non-ionizing radiation imaging specialties, such as magnetic resonance and ultrasound, are also considered for completeness. On the basis of these tasks, this book provides recommended minimum requirements for the academic education and clinical training of CQMPs, including recommendations for their accreditation, certification and registration, along with continuing professional development

Roles and Responsibilities, and Education and Training Requirements for Clinically Qualified Medical Physicists

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-08-15

The IAEA technical cooperation project Strengthening Medical Physics in Radiation Medicine was approved by the IAEA Board of Governors for the period 2009-2013 with the aim of ensuring the safe and effective diagnosis and treatment of patients. The IAEA, together with the World Health Organization and stakeholders from numerous medical physics professional societies worldwide, including the International Organization for Medical Physics (IOMP), the European Federation of Organisations for Medical Physics, the American Association of Physicists in Medicine (AAPM), the Latin American Medical Physics Association, the Asia-Oceania Federation of Organizations for Medical Physics, the European Society for Radiotherapy and Oncology, the European Commission and the International Radiation Protection Association, as well as regional counterparts from Africa, Asia, Europe and Latin America, met in Vienna in May 2009 to plan and coordinate the new project. A shortage of clinically qualified medical physicists (CQMPs), insufficient education and training (especially properly organized and coordinated clinical training), and lack of professional recognition were identified as the main problems to be addressed under this project. This publication was developed under the project framework in response to these findings. It aims, first, at defining appropriately and unequivocally the roles and responsibilities of a CQMP in specialties of medical physics related to the use of ionizing radiation, such as radiation therapy, nuclear medicine, and diagnostic and interventional radiology. Important, non-ionizing radiation imaging specialties, such as magnetic resonance and ultrasound, are also considered for completeness. On the basis of these tasks, this book provides recommended minimum requirements for the academic education and clinical training of CQMPs, including recommendations for their accreditation, certification and registration, along with continuing professional development

38 CFR 61.12 - Threshold requirements for capital grant applications.

Science.gov (United States)

2010-07-01

... for capital grant applications. 61.12 Section 61.12 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.12 Threshold requirements for capital grant applications. To be eligible for a capital grant, an applicant must meet the...

Medical applications of nuclear physics and heavy-ion beams

International Nuclear Information System (INIS)

Alonso, Jose R.

2000-01-01

Isotopes and accelerators, hallmarks of nuclear physics, are finding increasingly sophisticated and effective applications in the medical field. Diagnostic and therapeutic uses of radioisotopes are now a $10B/yr business worldwide, with over 10 million procedures and patient studies performed every year. This paper will discuss the use of isotopes for these applications. In addition, beams of protons and heavy ions are being more and more widely used clinically for treatment of malignancies. To be discussed here as well will be the rationale and techniques associated with charged-particle therapy, and the progress in implementation and optimization of these technologies for clinical use

Plasma treatment: A Novel Medical Application

International Nuclear Information System (INIS)

Boonyawan, Dheerawan

2015-01-01

Cold atmospheric plasma (CAP) for the medical treatment is a new field in plasma application, called plasma medicine. CAP contrains mix of excited atoms and molecules, UV photons, charged particles as well as reactive oxygen species (ROS) and reactive nitrogen species (RNS). Typical species in air CAPs are O 3 , OH, N x , and HNO x . Two cold atomospheric plasma devices were utiized (either in an indirect or a direct way) for the treatment of physiologically healthy volunterrs, The results show that CAP is effective againts chronic wound infections and/ or for skin treatment in clinical trials. The current developments in this field have fuelled the hope that CAP could be, and interesting new therapeutic apptoach in the treatment of cancer.

Early-career researchers in medical applications @ CERN | 6 June | Main Auditorium

CERN Multimedia

2016-01-01

  Discover how technological advances for high-energy physics have become essential tools for modern medicine. CERN seeks to answer fundamental questions about the Universe, and this mission naturally contributes to advancing the frontiers of technology. State-of-the-art techniques developed for particle accelerators, detectors, and physics computing have applications beyond the high-energy physics community in the medical field. These applications now have an essential role in clinical practices and medical research centres: from imaging devices, accelerator-technology dedicated to cancer therapy, to simulations and data science tools. This knowledge transfer from the high energy physics community to innovation in other fields is an inherent component of CERN’s mission and culture. It fuels scientific collaboration and technological advances, and drives innovation. In addition, it motivates future generations of scientists, and contributes to the public awareness of the impact of fu...

Ionizing radiation sources used in medical applications in Brazil

International Nuclear Information System (INIS)

Araujo, A.M.C.; Carlos, M.T.; Cruz, L.R.F.; Domingues, C.; Farias, J.T.; Ferreira, R.; Figueiredo, L.; Peixoto, J.E.; Oliveira, S.M.V.; Drexler, G.

1991-02-01

Preliminary data about ionizing radiation sources used in medical applications and obtained through a national programme by IRD/CNEN together with Brazilian health authorities are presented. The data presentation follows, as close as possible, recommendations given by the United Nations Scientific Committee on Effects of Atomic Radiation (UNSCEAR). This programme has two main aims: First: to contribute for research in the field of ionizing radiation effects and risks including information about equipment quality control and procedures adopted by professionals working in Radiation Medicine. Second: to investigate the radiation protection status in Brazil, in order to give assistance to Brazilian health authorities for planning regional radiation programmes and training programmes for medical staffs. (F.E.). 13 refs, 19 figs, 34 tabs

PREPARING FOR EXASCALE: ORNL Leadership Computing Application Requirements and Strategy

Energy Technology Data Exchange (ETDEWEB)

Joubert, Wayne [ORNL; Kothe, Douglas B [ORNL; Nam, Hai Ah [ORNL

2009-12-01

In 2009 the Oak Ridge Leadership Computing Facility (OLCF), a U.S. Department of Energy (DOE) facility at the Oak Ridge National Laboratory (ORNL) National Center for Computational Sciences (NCCS), elicited petascale computational science requirements from leading computational scientists in the international science community. This effort targeted science teams whose projects received large computer allocation awards on OLCF systems. A clear finding of this process was that in order to reach their science goals over the next several years, multiple projects will require computational resources in excess of an order of magnitude more powerful than those currently available. Additionally, for the longer term, next-generation science will require computing platforms of exascale capability in order to reach DOE science objectives over the next decade. It is generally recognized that achieving exascale in the proposed time frame will require disruptive changes in computer hardware and software. Processor hardware will become necessarily heterogeneous and will include accelerator technologies. Software must undergo the concomitant changes needed to extract the available performance from this heterogeneous hardware. This disruption portends to be substantial, not unlike the change to the message passing paradigm in the computational science community over 20 years ago. Since technological disruptions take time to assimilate, we must aggressively embark on this course of change now, to insure that science applications and their underlying programming models are mature and ready when exascale computing arrives. This includes initiation of application readiness efforts to adapt existing codes to heterogeneous architectures, support of relevant software tools, and procurement of next-generation hardware testbeds for porting and testing codes. The 2009 OLCF requirements process identified numerous actions necessary to meet this challenge: (1) Hardware capabilities must be

PREPARING FOR EXASCALE: ORNL Leadership Computing Application Requirements and Strategy

International Nuclear Information System (INIS)

Joubert, Wayne; Kothe, Douglas B.; Nam, Hai Ah

2009-01-01

In 2009 the Oak Ridge Leadership Computing Facility (OLCF), a U.S. Department of Energy (DOE) facility at the Oak Ridge National Laboratory (ORNL) National Center for Computational Sciences (NCCS), elicited petascale computational science requirements from leading computational scientists in the international science community. This effort targeted science teams whose projects received large computer allocation awards on OLCF systems. A clear finding of this process was that in order to reach their science goals over the next several years, multiple projects will require computational resources in excess of an order of magnitude more powerful than those currently available. Additionally, for the longer term, next-generation science will require computing platforms of exascale capability in order to reach DOE science objectives over the next decade. It is generally recognized that achieving exascale in the proposed time frame will require disruptive changes in computer hardware and software. Processor hardware will become necessarily heterogeneous and will include accelerator technologies. Software must undergo the concomitant changes needed to extract the available performance from this heterogeneous hardware. This disruption portends to be substantial, not unlike the change to the message passing paradigm in the computational science community over 20 years ago. Since technological disruptions take time to assimilate, we must aggressively embark on this course of change now, to insure that science applications and their underlying programming models are mature and ready when exascale computing arrives. This includes initiation of application readiness efforts to adapt existing codes to heterogeneous architectures, support of relevant software tools, and procurement of next-generation hardware testbeds for porting and testing codes. The 2009 OLCF requirements process identified numerous actions necessary to meet this challenge: (1) Hardware capabilities must be

Medical image registration algorithms assesment Bronze Standard application enactment on grids using the MOTEUR workflow engine

CERN Document Server

Glatard, T; Pennec, X

2006-01-01

Medical image registration is pre-processing needed for many medical image analysis procedures. A very large number of registration algorithms are available today, but their performance is often not known and very difficult to assess due to the lack of gold standard. The Bronze Standard algorithm is a very data and compute intensive statistical approach for quantifying registration algorithms accuracy. In this paper, we describe the Bronze Standard application and we discuss the need for grids to tackle such computations on medical image databases. We demonstrate MOTEUR, a service-based workflow engine optimized for dealing with data intensive applications. MOTEUR eases the enactment of the Bronze Standard and similar applications on the EGEE production grid infrastructure. It is a generic workflow engine, based on current standards and freely available, that can be used to instrument legacy application code at low cost.

Technical specifications requirements: Automated reasoning applications

International Nuclear Information System (INIS)

Lidsky, L.M.; Dobrzeniecki, A.B.

1990-03-01

Several software systems were developed and tested to determine what advantages could be gained from explicitly translating complicated regulatory requirements into computerized relationships. The Technical Specifications for US nuclear power plants were chosen as the test-bed application domain, and two analysis systems were developed to monitor plant compliance with operational limits, and track and schedule equipment test and maintenance activities mandated by Technical Specifications. Choosing PROLOG as the computer language to represent these regulatory requirements resulted in a natural match between the semantic structure of the written specifications and the corollary coded rules. Additional research results affirmed the utility of declarative programming styles, explicit management of problem complexity, and attention to the robustness and flexibility of the overall software systems. 5 refs., 2 figs

A CMMI-based approach for medical software project life cycle study.

Science.gov (United States)

Chen, Jui-Jen; Su, Wu-Chen; Wang, Pei-Wen; Yen, Hung-Chi

2013-01-01

In terms of medical techniques, Taiwan has gained international recognition in recent years. However, the medical information system industry in Taiwan is still at a developing stage compared with the software industries in other nations. In addition, systematic development processes are indispensable elements of software development. They can help developers increase their productivity and efficiency and also avoid unnecessary risks arising during the development process. Thus, this paper presents an application of Light-Weight Capability Maturity Model Integration (LW-CMMI) to Chang Gung Medical Research Project (CMRP) in the Nuclear medicine field. This application was intended to integrate user requirements, system design and testing of software development processes into three layers (Domain, Concept and Instance) model. Then, expressing in structural System Modeling Language (SysML) diagrams and converts part of the manual effort necessary for project management maintenance into computational effort, for example: (semi-) automatic delivery of traceability management. In this application, it supports establishing artifacts of "requirement specification document", "project execution plan document", "system design document" and "system test document", and can deliver a prototype of lightweight project management tool on the Nuclear Medicine software project. The results of this application can be a reference for other medical institutions in developing medical information systems and support of project management to achieve the aim of patient safety.

Data bank applications of a nuclear medical computer system

International Nuclear Information System (INIS)

Hale, T.I.; Jucker, A.; Haering, W.; Schmid, B.

1980-01-01

Computer systems in nuclear medicine are normally not used for data bank applications. A concept for a PDP-11-34 with RK 05 disc is presented, which serves the needs of data manipulations of a medium sized hospital including management of patient data, pharma stock control etc. besides specific use for nuclear medical work with absolute priority. The program is available upon request. (orig.) [de

Applications of nuclear technique in environmental and medical science

International Nuclear Information System (INIS)

Shi Xianfeng; Shen Hao; Liu Bo; Sun Minde; Yao Huiying; Zhou Shijun; Mi Yong

2001-01-01

The serious environmental pollution problem and application of the nuclear technique in environmental and medical sciences were discussed. The analysed results of the elemental distribution of particles in automobile exhaust, the aerosol particle of different size and the effect of Rare Earth on cells were reported. The authors can obtain some information related to element concentration. It offers a convenient method in inspecting the environmental pollution

Proceedings of the tenth annual symposium on computer applications in medical care

International Nuclear Information System (INIS)

Orthner, H.F.

1988-01-01

This book covers the proceedings of the tenth annual symposium on Computer Applications in Medical Care. The papers include: Image processing in cardiovascular radiology and radiologic automated diagnosis (RAD)

The perceptions of anatomists in the US and Europe of the skills and attributes required of newly-recruited medical students.

Science.gov (United States)

Moxham, Bernard J; Plaisant, Odile; Lignier, Baptiste; Brahim, Feisal

2018-05-01

Admission procedures for recruiting students to medical school vary considerably across the world. Notwithstanding such variability, it is important to know what skills and attributes (including attitudes and personality traits) are required of the students by their teachers on entering medical school. Anatomists are often the teachers who first meet the students as they enter medical school and this report analyses, by means of a paper-based questionnaire, the putative skills required of their medical students by anatomists from the U.S.A. and Europe. Questionnaires were distributed to 150 anatomists, of varying ages and teaching experience, with 108 responding with completed questionnaires (i.e. 72% returns). The findings from a questionnaire suggest that there are few differences between anatomists in the U.S.A. and Europe, even though medical students are postgraduates in the U.S.A. but undergraduates in Europe. Furthermore, the skill requirements expected of the students differed only slightly according to the gender and age of the anatomists and to whether or not they had clinical qualifications. In order of perceived importance, the most important skills and attributes required of the students were found to be: good study skills, memory/factual retention, conscientiousness, emotional stability, understanding of biology (but not chemistry, physics, mathematics, statistics, or understanding of the scientific method), life-long learning skills, ability to study independently, problem-solving abilities, readiness to be challenged, communication skills, and teamwork skills. Anatomists within the U.S.A. and Europe essentially agree on the skills and attributes initially required of their medical students, as well as those not deemed initially important. These findings are presented with the view of enhancing admission policies and procedures for admitting students into medical schools. Copyright © 2018. Published by Elsevier GmbH.

An approach for access differentiation design in medical distributed applications built on databases.

Science.gov (United States)

Shoukourian, S K; Vasilyan, A M; Avagyan, A A; Shukurian, A K

1999-01-01

A formalized "top to bottom" design approach was described in [1] for distributed applications built on databases, which were considered as a medium between virtual and real user environments for a specific medical application. Merging different components within a unified distributed application posits new essential problems for software. Particularly protection tools, which are sufficient separately, become deficient during the integration due to specific additional links and relationships not considered formerly. E.g., it is impossible to protect a shared object in the virtual operating room using only DBMS protection tools, if the object is stored as a record in DB tables. The solution of the problem should be found only within the more general application framework. Appropriate tools are absent or unavailable. The present paper suggests a detailed outline of a design and testing toolset for access differentiation systems (ADS) in distributed medical applications which use databases. The appropriate formal model as well as tools for its mapping to a DMBS are suggested. Remote users connected via global networks are considered too.

Visual servoing in medical robotics: a survey. Part II: tomographic imaging modalities--techniques and applications.

Science.gov (United States)

Azizian, Mahdi; Najmaei, Nima; Khoshnam, Mahta; Patel, Rajni

2015-03-01

Intraoperative application of tomographic imaging techniques provides a means of visual servoing for objects beneath the surface of organs. The focus of this survey is on therapeutic and diagnostic medical applications where tomographic imaging is used in visual servoing. To this end, a comprehensive search of the electronic databases was completed for the period 2000-2013. Existing techniques and products are categorized and studied, based on the imaging modality and their medical applications. This part complements Part I of the survey, which covers visual servoing techniques using endoscopic imaging and direct vision. The main challenges in using visual servoing based on tomographic images have been identified. 'Supervised automation of medical robotics' is found to be a major trend in this field and ultrasound is the most commonly used tomographic modality for visual servoing. Copyright © 2014 John Wiley & Sons, Ltd.

75 FR 76260 - Conforming Changes to Applicant Submission Requirements; Implementing Federal Financial Report...

Science.gov (United States)

2010-12-08

... HUD regulations to reference the new governmentwide Federal Financial Report (FFR) approved by the... task of filing required financial reports. Similarly, CCR registration has been required of applicants...] RIN 2501-AD50 Conforming Changes to Applicant Submission Requirements; Implementing Federal Financial...

40 CFR 74.17 - Application requirements for process sources. [Reserved

Science.gov (United States)

2010-07-01

... requirements for process sources. [Reserved] ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Application requirements for process sources. [Reserved] 74.17 Section 74.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

Application of Irradiation. Application to polymer processing, exhaust gas treatment, sterilization of medical instruments and food

Energy Technology Data Exchange (ETDEWEB)

Sawai, Takeshi; Sawai, Teruko

2000-03-01

Many fields such as industry, agriculture, medical treatment and environment use radiation. This report explained some examples of irradiation applications. Radiation source is {sup 60}Co {gamma}-ray. Polymer industry use radiation for radiation curing (thermally stable polymer), tire, expanded polymer, radiation induced graft copolymerization and electron beam curing. On environmental conservation, radiation is used for elimination of NOx and SOx in exhaust combustion gas. In the medical treatment, radiation is applied to sterilization of medical instruments, that occupied about 50% volume, and blood for transfusion, which is only one method to prevent GVHD after transfusion. On agriculture, irradiation to spice, dry vegetable, frozen kitchen, potato and garlic are carried out in 30 countries. However, potato is only a kind food in Japan. Radiation breeding and pest control are put in practice. (S.Y.)

Development of Knowledge Intensive Applications for Hospital

Science.gov (United States)

Kim, Jongho; Hong, Han-Kuk; Jang, Gil-Sang; Kim, Joung Yeon; Kim, Taehun

Most studies of medical intelligence system have focused on the development of backend data repositories rather than frontend user applications. Also, they tend to lack systematic development models which demonstrate how user requirements inform system design and implementation. For these reasons, it is highly desirable to show the process of eliciting knowledge requirements in addition to the development process for knowledge-intensive applications. This research covers the implementation of a medical intelligence system based on analysis of knowledge requirements such as OLAP (On-line Analytical Processing) fundamental functionalities and knowledge types. The proposed medical intelligence system provides health care providers and their supporters with the ability to draw meaningful insights from very large, complex data sets. A real life case is presented to illustrate the system’s practical usage. Six application packages are defined, namely: explorer, analyzer, reporter, statistician, visualizer, and meta administrator. Finally, the study concludes with an evaluation of the developed system and future research directions.

Radiological protection, safety and security issues in the industrial and medical applications of radiation sources

International Nuclear Information System (INIS)

Vaz, Pedro

2015-01-01

The use of radiation sources, namely radioactive sealed or unsealed sources and particle accelerators and beams is ubiquitous in the industrial and medical applications of ionizing radiation. Besides radiological protection of the workers, members of the public and patients in routine situations, the use of radiation sources involves several aspects associated to the mitigation of radiological or nuclear accidents and associated emergency situations. On the other hand, during the last decade security issues became burning issues due to the potential malevolent uses of radioactive sources for the perpetration of terrorist acts using RDD (Radiological Dispersal Devices), RED (Radiation Exposure Devices) or IND (Improvised Nuclear Devices). A stringent set of international legally and non-legally binding instruments, regulations, conventions and treaties regulate nowadays the use of radioactive sources. In this paper, a review of the radiological protection issues associated to the use of radiation sources in the industrial and medical applications of ionizing radiation is performed. The associated radiation safety issues and the prevention and mitigation of incidents and accidents are discussed. A comprehensive discussion of the security issues associated to the global use of radiation sources for the aforementioned applications and the inherent radiation detection requirements will be presented. Scientific, technical, legal, ethical, socio-economic issues are put forward and discussed. - Highlights: • The hazards associated to the use of radioactive sources must be taken into account. • Security issues are of paramount importance in the use of radioactive sources. • Radiation sources can be used to perpetrate terrorist acts (RDDs, INDs, REDs). • DSRS and orphan sources trigger radiological protection, safety and security concerns. • Regulatory control, from cradle to grave, of radioactive sources is mandatory.

USSTRIDE program is associated with competitive Black and Latino student applicants to medical school

OpenAIRE

Campbell, Kendall M.; Berne-Anderson, Thesla; Wang, Aihua; Dormeus, Guy; Rodríguez, José E.

2014-01-01

Purpose: We compared MCAT scores, grade point averages (GPAs), and medical school acceptance rates of Black and Latino students in an outreach program called Undergraduate Science Students Together Reaching Instructional Diversity and Excellence (USSTRIDE) to non-USSTRIDE students. We hypothesized that Black and Latino participants in USSTRIDE had higher acceptance rates to medical school, higher MCAT scores, and college GPAs when compared to other Black and Latino medical school applicants f...

NASA requirements and applications environments for electrical power wiring

International Nuclear Information System (INIS)

Stavnes, M.W.; Hammond, A.N.

1992-01-01

Serious problems can occur from insulation failures in the wiring harnesses of aerospace vehicles. In most recorded incidents, the failures have been identified to be the result of arc tracking, the propagation of an arc along wiring bundles through degradation of insulation. Propagation of the arc can lead to the loss of the entire wiring harness and the functions which it supports. While an extensive database of testing for arc track resistant wire insulations have been developed for aircraft applications, the counterpart requirements for spacecraft are very limited. This paper presents the electrical, thermal, mechanical, chemical, and operational requirements for specification and testing of candidate wiring systems for spacecraft applications

ELIMED, MEDical and multidisciplinary applications at ELI-Beamlines

International Nuclear Information System (INIS)

Schillaci, F; Anzalone, A; Cirrone, G A P; Cuttone, G; Musumarra, A; Pisciotta, P; Romano, F; Romano, F P; Carpinelli, M; Cutroneo, M; De Martinis, C; Giove, D; Korn, G; Maggiore, M; Margarone, D; Manti, L; Perozziello, F M; Petrovic, I; Ristic-Fira, A; Renis, M

2014-01-01

ELI-Beamlines is one of the pillars of the pan-European project ELI (Extreme Light Infrastructure). It will be an ultra high-intensity, high repetition-rate, femtosecond laser facility whose main goal is generation and applications of high-brightness X-ray sources and accelerated charged particles in different fields. Particular care will be devoted to the potential applicability of laser-driven ion beams for medical treatments of tumors. Indeed, such kind of beams show very interesting peculiarities and, moreover, laser-driven based accelerators can really represent a competitive alternative to conventional machines since they are expected to be more compact in size and less expensive. The ELIMED project was launched thanks to a collaboration established between FZU-ASCR (ELI-Beamlines) and INFN-LNS researchers. Several European institutes have already shown a great interest in the project aiming to explore the possibility to use laser-driven ion (mostly proton) beams for several applications with a particular regard for medical ones. To reach the project goal several tasks need to be fulfilled, starting from the optimization of laser-target interaction to dosimetric studies at the irradiation point at the end of a proper designed transport beam-line. Researchers from LNS have already developed and successfully tested a high-dispersive power Thomson Parabola Spectrometer, which is the first prototype of a more performing device to be used within the ELIMED project. Also a Magnetic Selection System able to produce a small pencil beam out of a wide energy distribution of ions produced in laser-target interaction has been realized and some preliminary work for its testing and characterization is in progress. In this contribution the status of the project will be reported together with a short description of the of the features of device recently developed.

Smartphone application for mechanical quality assurance of medical linear accelerators

Science.gov (United States)

Kim, Hwiyoung; Lee, Hyunseok; In Park, Jong; Choi, Chang Heon; Park, So-Yeon; Kim, Hee Jung; Kim, Young Suk; Ye, Sung-Joon

2017-06-01

Mechanical quality assurance (QA) of medical linear accelerators consists of time-consuming and human-error-prone procedures. We developed a smartphone application system for mechanical QA. The system consists of two smartphones: one attached to a gantry for obtaining real-time information on the mechanical parameters of the medical linear accelerator, and another displaying real-time information via a Bluetooth connection with the former. Motion sensors embedded in the smartphone were used to measure gantry and collimator rotations. Images taken by the smartphone’s high-resolution camera were processed to evaluate accuracies of jaw-positioning, crosshair centering and source-to-surface distance (SSD). The application was developed using Android software development kit and OpenCV library. The accuracy and precision of the system was validated against an optical rotation stage and digital calipers, prior to routine QA measurements of five medical linear accelerators. The system accuracy and precision in measuring angles and lengths were determined to be 0.05  ±  0.05° and 0.25  ±  0.14 mm, respectively. The mean absolute errors (MAEs) in QA measurements of gantry and collimator rotation were 0.05  ±  0.04° and 0.05  ±  0.04°, respectively. The MAE in QA measurements of light field was 0.39  ±  0.36 mm. The MAEs in QA measurements of crosshair centering and SSD were 0.40  ±  0.35 mm and 0.41  ±  0.32 mm, respectively. In conclusion, most routine mechanical QA procedures could be performed using the smartphone application system with improved precision and within a shorter time-frame, while eliminating potential human errors.

Smartphone application for mechanical quality assurance of medical linear accelerators.

Science.gov (United States)

Kim, Hwiyoung; Lee, Hyunseok; Park, Jong In; Choi, Chang Heon; Park, So-Yeon; Kim, Hee Jung; Kim, Young Suk; Ye, Sung-Joon

2017-06-07

Mechanical quality assurance (QA) of medical linear accelerators consists of time-consuming and human-error-prone procedures. We developed a smartphone application system for mechanical QA. The system consists of two smartphones: one attached to a gantry for obtaining real-time information on the mechanical parameters of the medical linear accelerator, and another displaying real-time information via a Bluetooth connection with the former. Motion sensors embedded in the smartphone were used to measure gantry and collimator rotations. Images taken by the smartphone's high-resolution camera were processed to evaluate accuracies of jaw-positioning, crosshair centering and source-to-surface distance (SSD). The application was developed using Android software development kit and OpenCV library. The accuracy and precision of the system was validated against an optical rotation stage and digital calipers, prior to routine QA measurements of five medical linear accelerators. The system accuracy and precision in measuring angles and lengths were determined to be 0.05  ±  0.05° and 0.25  ±  0.14 mm, respectively. The mean absolute errors (MAEs) in QA measurements of gantry and collimator rotation were 0.05  ±  0.04° and 0.05  ±  0.04°, respectively. The MAE in QA measurements of light field was 0.39  ±  0.36 mm. The MAEs in QA measurements of crosshair centering and SSD were 0.40  ±  0.35 mm and 0.41  ±  0.32 mm, respectively. In conclusion, most routine mechanical QA procedures could be performed using the smartphone application system with improved precision and within a shorter time-frame, while eliminating potential human errors.

A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and Organ Applications

Directory of Open Access Journals (Sweden)

Kan Wang

2017-10-01

Full Text Available Medical models, or “phantoms,” have been widely used for medical training and for doctor-patient interactions. They are increasingly used for surgical planning, medical computational models, algorithm verification and validation, and medical devices development. Such new applications demand high-fidelity, patient-specific, tissue-mimicking medical phantoms that can not only closely emulate the geometric structures of human organs, but also possess the properties and functions of the organ structure. With the rapid advancement of three-dimensional (3D printing and 3D bioprinting technologies, many researchers have explored the use of these additive manufacturing techniques to fabricate functional medical phantoms for various applications. This paper reviews the applications of these 3D printing and 3D bioprinting technologies for the fabrication of functional medical phantoms and bio-structures. This review specifically discusses the state of the art along with new developments and trends in 3D printed functional medical phantoms (i.e., tissue-mimicking medical phantoms, radiologically relevant medical phantoms, and physiological medical phantoms and 3D bio-printed structures (i.e., hybrid scaffolding materials, convertible scaffolds, and integrated sensors for regenerated tissues and organs.

Framework conditions and requirements to ensure the technical functional safety of reprocessed medical devices.

Science.gov (United States)

Kraft, Marc

2008-09-03

Testing and restoring technical-functional safety is an essential part of medical device reprocessing. Technical functional tests have to be carried out on the medical device in the course of the validation of reprocessing procedures. These ensure (in addition to the hygiene tests) that the reprocessing procedure is suitable for the medical device. Functional tests are, however, also a part of reprocessing procedures. As a stage in the reprocessing, they ensure for the individual medical device that no damage or other changes limit the performance. When determining which technical-functional tests are to be carried out, the current technological standard has to be taken into account in the form of product-specific and process-oriented norms. Product-specific norms primarily define safety-relevant requirements. The risk management method described in DIN EN ISO 14971 is the basis for recognising hazards; the likelihood of such hazards arising can be minimised through additional technical-functional tests, which may not yet have been standardised. Risk management is part of a quality management system, which must be bindingly certified for manufacturers and processors of critical medical devices with particularly high processing demands by a body accredited by the competent authority.

Radiation environmental impact assessment of the radioisotope's application on nuclear medical science

International Nuclear Information System (INIS)

Liu Hongshi

2004-01-01

The radiation environmental impact assessment of the radioisotope's application on nuclear medical science is introduced, including the assessment criteria, the assessment methods and the environmental impact assessment of three wastes emission. (authors)

Wireless Technology Use Case Requirement Analysis for Future Space Applications

Science.gov (United States)

Abedi, Ali; Wilkerson, DeLisa

2016-01-01

This report presents various use case scenarios for wireless technology -including radio frequency (RF), optical, and acoustic- and studies requirements and boundary conditions in each scenario. The results of this study can be used to prioritize technology evaluation and development and in the long run help in development of a roadmap for future use of wireless technology. The presented scenarios cover the following application areas: (i) Space Vehicles (manned/unmanned), (ii) Satellites and Payloads, (iii) Surface Explorations, (iv) Ground Systems, and (v) Habitats. The requirement analysis covers two parallel set of conditions. The first set includes the environmental conditions such as temperature, radiation, noise/interference, wireless channel characteristics and accessibility. The second set of requirements are dictated by the application and may include parameters such as latency, throughput (effective data rate), error tolerance, and reliability. This report provides a comprehensive overview of all requirements from both perspectives and details their effects on wireless system reliability and network design. Application area examples are based on 2015 NASA Technology roadmap with specific focus on technology areas: TA 2.4, 3.3, 5.2, 5.5, 6.4, 7.4, and 10.4 sections that might benefit from wireless technology.

Medical Cyclotrons

Science.gov (United States)

Friesel, D. L.; Antaya, T. A.

Particle accelerators were initially developed to address specific scientific research goals, yet they were used for practical applications, particularly medical applications, within a few years of their invention. The cyclotron's potential for producing beams for cancer therapy and medical radioisotope production was realized with the early Lawrence cyclotrons and has continued with their more technically advanced successors — synchrocyclotrons, sector-focused cyclotrons and superconducting cyclotrons. While a variety of other accelerator technologies were developed to achieve today's high energy particles, this article will chronicle the development of one type of accelerator — the cyclotron, and its medical applications. These medical and industrial applications eventually led to the commercial manufacture of both small and large cyclotrons and facilities specifically designed for applications other than scientific research.

Study on the Application Mode and Legal Protection of Green Materials in Medical-Nursing Combined Building

Science.gov (United States)

Zhiyong, Xian

2017-09-01

In the context of green development, green materials are the future trend of Medical-Nursing Combined building. This paper summarizes the concept and types of green building materials. Then, on the basis of existing research, it constructs the green material system framework of Medical-Nursing Combined building, puts forward the application mode of green building materials, and studies the policy and legal protection of green material application.

Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

NARCIS (Netherlands)

Stamatialis, Dimitrios; Papenburg, B.J.; Girones nogue, Miriam; Saiful, S.; Bettahalli Narasimha, M.S.; Schmitmeier, Stephanie; Wessling, Matthias

2008-01-01

This paper covers the main medical applications of artificial membranes. Specific attention is given to drug delivery systems, artificial organs and tissue engineering which seem to dominate the interest of the membrane community this period. In all cases, the materials, methods and the current

User Requirements & Demand for Services and Applications in PNs

DEFF Research Database (Denmark)

Jiang, Bo

This paper focuses on the methodology for analyses of user requirements and demand for specific services and applications in relation to personal networks (PNs). The paper has a strong user-centric approach to service and application development based on the widely accepted fact that future servi...... demand for services and applications in a PN setting. This further includes discussion of service categorization, service description and human-value issues as personalization, security and privacy, billing and price and human-computer interaction paradigms....

[Development and evaluation of the medical imaging distribution system with dynamic web application and clustering technology].

Science.gov (United States)

Yokohama, Noriya; Tsuchimoto, Tadashi; Oishi, Masamichi; Itou, Katsuya

2007-01-20

It has been noted that the downtime of medical informatics systems is often long. Many systems encounter downtimes of hours or even days, which can have a critical effect on daily operations. Such systems remain especially weak in the areas of database and medical imaging data. The scheme design shows the three-layer architecture of the system: application, database, and storage layers. The application layer uses the DICOM protocol (Digital Imaging and Communication in Medicine) and HTTP (Hyper Text Transport Protocol) with AJAX (Asynchronous JavaScript+XML). The database is designed to decentralize in parallel using cluster technology. Consequently, restoration of the database can be done not only with ease but also with improved retrieval speed. In the storage layer, a network RAID (Redundant Array of Independent Disks) system, it is possible to construct exabyte-scale parallel file systems that exploit storage spread. Development and evaluation of the test-bed has been successful in medical information data backup and recovery in a network environment. This paper presents a schematic design of the new medical informatics system that can be accommodated from a recovery and the dynamic Web application for medical imaging distribution using AJAX.

BIOANALYTICAL STANDARDIZING FOR SEROLOGICAL DIAGNOSTIC MEDICAL DEVICES

OpenAIRE

A. Yu. Galkin; A. G. Komar; A. A. Grigorenko

2015-01-01

In article we analyzed national and international regulations concerning the quality and safety of medical devices for in vitro diagnostics. We discussed the possibility of a partial application of the recommendations of the State Pharmacopoeia of Ukraine to this type of product. The main guiding regulatory documents establishing requirements for quality and safety tools for the serological diagnosis products are The technical regulation on medical devices for the diagnosis in vitro, DSTU ISO...

An Overview of Mechanical Properties and Material Modeling of Polylactide (PLA) for Medical Applications.

Science.gov (United States)

Bergström, Jörgen S; Hayman, Danika

2016-02-01

This article provides an overview of the connection between the microstructural state and the mechanical response of various bioresorbable polylactide (PLA) devices for medical applications. PLLA is currently the most commonly used material for bioresorbable stents and sutures, and its use is increasing in many other medical applications. The non-linear mechanical response of PLLA, due in part to its low glass transition temperature (T g ≈ 60 °C), is highly sensitive to the molecular weight and molecular orientation field, the degree of crystallinity, and the physical aging time. These microstructural parameters can be tailored for specific applications using different resin formulations and processing conditions. The stress-strain, deformation, and degradation response of a bioresorbable medical device is also strongly dependent on the time history of applied loads and boundary conditions. All of these factors can be incorporated into a suitable constitutive model that captures the multiple physics that are involved in the device response. Currently developed constitutive models already provide powerful computations simulation tools, and more progress in this area is expected to occur in the coming years.

Security Issues in Healthcare Applications Using Wireless Medical Sensor Networks: A Survey

OpenAIRE

Hoon-Jae Lee; Pardeep Kumar

2011-01-01

Healthcare applications are considered as promising fields for wireless sensor networks, where patients can be monitored using wireless medical sensor networks (WMSNs). Current WMSN healthcare research trends focus on patient reliable communication, patient mobility, and energy-efficient routing, as a few examples. However, deploying new technologies in healthcare applications without considering security makes patient privacy vulnerable. Moreover, the physiological data of an individual are ...

37 CFR 1.730 - Applicant for extension of patent term; signature requirements.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Applicant for extension of patent term; signature requirements. 1.730 Section 1.730 Patents, Trademarks, and Copyrights UNITED... for extension of patent term; signature requirements. (a) Any application for extension of a patent...

Country status of application, manufacturing and sterilization of single-use medical products

International Nuclear Information System (INIS)

Norimah Yusof

1986-01-01

The paper reviews the current status of application of single-use medical products in Malaysia. The status of their manufacturing and sterilization is also discussed. The increasing production of such items calls for a more reliable and efficient sterilization technique in particular, radiation sterilization. In line with the demand and the effort to increase local production of medical products, UTN would be providing irradiation service together with research and development in this particular field by 1988. (author)

A dual use case study of space technologies for terrestrial medical applications (Conference Presentation)

Science.gov (United States)

Cozmuta, Ioana

2017-05-01

Many challenges exist in understanding the human body as a whole, its adaptability, its resilience, its immunological response, its healing and regeneration power. New knowledge is usually obtained by exploring unique conditions and environments and space is one such variable. Primarily, these attributes have been studied in space for the purpose of understanding the effect of the space environment on long duration space travel. However a myriad of lessons learned have emerged that are important for terrestrial medicine problems such as cardiovascular changes, intracranial pressure changes, vision changes, reduced immunity, etc. For medical study purposes, the changes induced by the space environment on the human body are in general fast and predictable; they persist while in the space environment but also revert to the initial pre-flight healthy state upon return to Earth. This provides a unique cycle to study wellness and disease prediction as well as to develop more effective countermeasures for the benefit of people on earth. At a scientific level, the environment of space can be used to develop new lines of investigations and new knowledge to push the terrestrial state of the art (i.e. study of phase diagrams, identification of new system's states, etc). Moreover, the specialized requirements for space medicine have driven advances in terrestrial medical technologies in areas such as monitoring, diagnostic, prevention and treatment. This talk will provide an overview of compelling examples in key areas of interest for terrestrial medical applications.

Update on Research and Application of Problem-Based Learning in Medical Science Education

Science.gov (United States)

Fan, Chuifeng; Jiang, Biying; Shi, Xiuying; Wang, Enhua; Li, Qingchang

2018-01-01

Problem-based learning (PBL) is a unique form of pedagogy dedicated to developing students' self-learning and clinical practice skills. After several decades of development, although applications vary, PBL has been recognized all over the world and implemented by many medical schools. This review summarizes and updates the application and study of…

The development of a mandatory medical thesis in an urban medical school.

Science.gov (United States)

Ogunyemi, Dotun; Bazargan, Mohsen; Norris, Keith; Jones-Quaidoo, Sean; Wolf, Kenneth; Edelstein, Ronald; Baker, Richard S; Calmes, Daphne

2005-01-01

The objective of this study was to describe the development of a primary care medical student's thesis. In 1995, as part of its primary care clerkship, the Charles R. Drew University of Medicine and Science (Drew University), College of Medicine created a curriculum requiring medical students to develop, design, and implement a research project during their 2-year longitudinal clinical experience. For this study, we reviewed all student research projects generated between 1995 and 2004. Among the 112 research projects, topics covered included internal medicine (29.5%), obstetrics and gynecology (OBGYN; 22%), psychosocial issues (20.5%), pediatrics (9%), public health/epidemiology (8%), medical education (8%), and surgery (3%). Mentors included faculty from internal medicine (16%), dean's office (16%), pediatrics (13%), family medicine (11%), non-Drew faculty (10%), OBGYN (9%), psychiatry (9%), surgery (9%), emergency medicine (4%), and pathology/radiology departments (3%). The students' survey showed that 83% agreed that the mentors were valuable, 72% admitted that their knowledge about the research process was improved, about 50% indicated that they were more competitive during residency application, and 80% claimed that they obtained satisfaction from accomplishing a goal. Students are able to conduct and present a primary care research project as a requirement of their medical training. Most students find the experience beneficial and positive.