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Sample records for medial septum diagonal

  1. Special function of nestin+neurons in the medial septum-diagonal band of Broca in adult rats

    Institute of Scientific and Technical Information of China (English)

    Yuhong Zhao; Kaihua Guo; Dongpei Li; Qunfang Yuan; Zhibin Yao

    2014-01-01

    Nestin+neurons have been shown to express choline acetyltransferase (ChAT) in the medial septum-diagonal band of Broca in adult rats. This study explored the projection of nestin+neu-rons to the olfactory bulb and the time course of nestin+neurons in the medial septum-diagonal band of Broca in adult rats during injury recovery after olfactory nerve transection. This study observed that all nestin+neurons were double-labeled with ChAT in the medial septum-diagonal band of Broca. Approximately 53.6%of nestin+neurons were projected to the olfactory bulb and co-labeled with fast blue. A large number of nestin+neurons were not present in each region of the medial septum-diagonal band of Broca. Nestin+neurons in the medial septum and vertical limb of the diagonal band of Broca showed obvious compensatory function. The number of nestin+neurons decreased to a minimum later than nestin-/ChAT+neurons in the medial sep-tum-diagonal band of Broca. The results suggest that nestin+cholinergic neurons may have a closer connection to olfactory bulb neurons. Nestin+cholinergic neurons may have a stronger tolerance to injury than Nestin-/ChAT+neurons. The difference between nestin+and nestin-/ChAT+neurons during the recovery process requires further investigations.

  2. Differential expression of voltage-gated K+ currents in medial septum/diagonal band complex neurons exhibiting distinct firing phenotypes

    OpenAIRE

    Garrido-Sanabria, Emilio R.; Perez-Cordova, Miriam G.; Colom, Luis V.

    2011-01-01

    The medial septum/diagonal band complex (MSDB) controls hippocampal excitability, rhythms and plastic processes. Medial septal neuronal populations display heterogeneous firing patterns. In addition, some of these populations degenerate during age-related disorders (e.g. cholinergic neurons). Thus, it is particularly important to examine the intrinsic properties of theses neurons in order to create new agents that effectively modulate hippocampal excitability and enhance memory processes. Her...

  3. Interconnection and synchronization of neuronal populations in the mouse medial septum/diagonal band of Broca.

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    Leão, Richardson N; Targino, Zé H; Colom, Luis V; Fisahn, André

    2015-02-01

    The medial septum/diagonal band of Broca (MS/DBB) is crucial for hippocampal theta rhythm generation (4-12 Hz). However, the mechanisms behind theta rhythmogenesis are still under debate. The MS/DBB consists, in its majority, of three neuronal populations that use acetylcholine, GABA, or glutamate as neurotransmitter. While the firing patterns of septal neurons enable the MS/DBB to generate rhythmic output critical for the generation of the hippocampal theta rhythm, the ability to synchronize these action potentials is dependent on the interconnectivity between the three major MS/DBB neuronal populations, yet little is known about intraseptal connections. Here we assessed the connectivity between pairs of MS/DBB neurons with paired patch-clamp recordings. We found that glutamatergic and GABAergic neurons provide intraseptal connections and produce sizable currents in MS/DBB postsynaptic cells. We also analyzed linear and nonlinear relationships between the action potentials fired by pairs of neurons belonging to various MS/DBB neuronal populations. Our results show that while the synchrony index for action potential firing was significantly higher in pairs of GABAergic neurons, coherence of action potential firing in the theta range was similarly low in all pairs analyzed. Recurrence analysis demonstrated that individual action potentials were more recurrent in cholinergic neurons than in other cell types. Implementing sparse connectivity in a computer model of the MS/DBB network reproduced our experimental data. We conclude that the interplay between the intrinsic membrane properties of different MS/DBB neuronal populations and the connectivity among these populations underlie the ability of the MS/DBB network to critically contribute to hippocampal theta rhythmogenesis.

  4. Parvalbumin-immunoreactive, fast-spiking neurons in the medial septum/diagonal band complex of the rat: intracellular recordings in vitro.

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    Morris, N P; Harris, S J; Henderson, Z

    1999-01-01

    The medial septum/diagonal band complex is composed predominantly of cholinergic and GABAergic neurons, and it projects to the hippocampal formation. A proportion of the GABAergic neurons contain parvalbumin, a calcium-binding protein that has previously been localized in fast-spiking, non-accommodating GABAergic neurons in the cerebral cortex and neostriatum. The aim of the present study was to determine whether parvalbumin is localized preferentially in a similar electrophysiological class of neuron in the medial septum/diagonal band complex. The study was carried out using in vitro intracellular recording, intracellular biocytin filling and parvalbumin immunocytochemistry. Three main classes of neurons were identified according to standard criteria: burst-firing, slow-firing and fast-firing neuronal populations. The fast-firing neurons were subdivided into two subpopulations based on whether or not they displayed accommodation. The fast-spiking, non-accommodating cells were furthermore found to be spontaneously active at resting potentials, and to possess action potentials of significantly (P studies showing parvalbumin to be localized solely in GABAergic neurons in the medial septum/diagonal band complex. In conclusion, these findings suggest the presence of a previously uncharacterized population of neurons in the medial septum/diagonal band complex that generate high-frequency, non-adaptive discharge. This property correlates with the localization of parvalbumin in these neurons, which suggests that parvalbumin fulfils the same role in the medial septum/diagonal band complex that it does in other parts of the brain. The fast-spiking neurons in the medial septum/diagonal band complex may play an essential role in the GABAergic influence of the septum on the hippocampal formation.

  5. Distribution and role of Kv3.1b in neurons in the medial septum diagonal band complex.

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    Henderson, Z; Lu, C B; Janzsó, G; Matto, N; McKinley, C E; Yanagawa, Y; Halasy, K

    2010-03-31

    The medial septum diagonal band complex (MS/DB) projects via cholinergic and GABAergic pathways to the hippocampus and plays a key role in the hippocampal theta rhythm. In the MS/DB we have previously described a population of fast spiking GABAergic neurons that contain parvalbumin and mediate theta frequency activity in vitro. The Kv3.1 potassium channel is a delayed rectifier channel that plays a major role in fast spiking neurons in the CNS, and has previously been localized in the MS/DB. To determine which cell types in the MS/DB express the Kv3.1b ion channel subunit, transgenic mice in which the expression of GABAergic and glutamate markers are associated with the expression of green fluorescent protein (GFP; GAD67-GFP and VGluT2-GFP mice, respectively) were used for immunofluorescence and axonal tract tracing. Electrophysiological studies were also carried out on rat MS/DB slices to examine the role of the Kv3.1 channel in theta frequency oscillations. The results for the MS/DB were as follows: (1) cholinergic cells did not express GFP in either GAD67-GFP or VGluT2-GFP mice, and there was GAD67 immunoreactivity in GFP-positive neurons in GAD67-GFP mice and in a small proportion (6%) of GFP-positive neurons in VGluT2-GFP mice. (2) Kv3.1b immunofluorescence was associated with the somata of GABAergic neurons, especially those that contained parvalbumin, and with a minority of glutamatergic neurons, but not with cholinergic neurons, and with GABAergic axonal terminal-like processes around certain GABAergic neurons. (3) Both Kv3.1b-positive and -negative GABAergic neurons were septo-hippocampal, and there was a minor projection to hippocampus from VGluT2-GFP neurons. (4) Kainate-induced theta oscillations in the MS/DB slice were potentiated rather than inhibited by the Kv3.1 blocker 4-aminopyridine, and this agent on its own produced theta frequency oscillations in MS/DB slices that were reduced by ionotropic glutamate and GABA receptor antagonists and abolished

  6. Cholinergic neuronal lesions in the medial septum and vertical limb of the diagonal bands of Broca induce contextual fear memory generalization and impair acquisition of fear extinction.

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    Knox, Dayan; Keller, Samantha M

    2016-06-01

    Previous research has shown that the ventral medial prefrontal cortex (vmPFC) and hippocampus (Hipp) are critical for extinction memory. Basal forebrain (BF) cholinergic input to the vmPFC and Hipp is critical for neural function in these substrates, which suggests BF cholinergic neurons may be critical for extinction memory. In order to test this hypothesis, we applied cholinergic lesions to different regions of the BF and observed the effects these lesions had on extinction memory. Complete BF cholinergic lesions induced contextual fear memory generalization, and this generalized fear was resistant to extinction. Animals with complete BF cholinergic lesions could not acquire cued fear extinction. Restricted cholinergic lesions in the medial septum and vertical diagonal bands of Broca (MS/vDBB) mimicked the effects that BF cholinergic lesions had on contextual fear memory generalization and acquisition of fear extinction. Cholinergic lesions in the horizontal diagonal band of Broca and nucleus basalis (hDBB/NBM) induced a small deficit in extinction of generalized contextual fear memory with no accompanying deficits in cued fear extinction. The results of this study reveal that MS/vDBB cholinergic neurons are critical for inhibition and extinction of generalized contextual fear memory, and via this process, may be critical for acquisition of cued fear extinction. Further studies delineating neural circuits and mechanisms through which MS/vDBB cholinergic neurons facilitate these emotional memory processes are needed. © 2015 Wiley Periodicals, Inc.

  7. Activation of serotonin2A receptors in the medial septum-diagonal band of Broca complex enhanced working memory in the hemiparkinsonian rats.

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    Li, Li-Bo; Zhang, Li; Sun, Yi-Na; Han, Ling-Na; Wu, Zhong-Heng; Zhang, Qiao-Jun; Liu, Jian

    2015-04-01

    Serotonin2A (5-HT2A) receptors are highly expressed in the medial septum-diagonal band of Broca complex (MS-DB), especially in parvalbumin (PV)-positive neurons linked to hippocampal theta rhythm, which is involved in cognition. Cognitive impairments commonly occur in Parkinson's disease. Here we performed behavioral, electrophysiological, neurochemical and immunohistochemical studies in rats with complete unilateral 6-hydroxydopamine lesions of the medial forebrain bundle (MFB) to assess the importance of dopamine (DA) depletion and MS-DB 5-HT2A receptors for working memory. The MFB lesions resulted in working memory impairment and decreases in firing rate and density of MS-DB PV-positive neurons, peak frequency of hippocampal theta rhythm, and DA levels in septohippocampal system and medial prefrontal cortex (mPFC) compared to control rats. Intra-MS-DB injection of high affinity 5-HT2A receptor agonist TCB-2 enhanced working memory, increased firing rate of PV-positive neurons and peak frequency of hippocampal theta rhythm, elevated DA levels in the hippocampus and mPFC, and decreased 5-HT level in the hippocampus in control and lesioned rats. Compared to control rats, the duration of the excitatory effect produced by TCB-2 on the firing rate of PV-positive neurons was markedly shortened in lesioned rats, indicating dysfunction of 5-HT2A receptors. These findings suggest that unilateral lesions of the MFB in rats induced working memory deficit, and activation of MS-DB 5-HT2A receptors enhanced working memory, which may be due to changes in the activity of septohippocampal network and monoamine levels in the hippocampus and mPFC.

  8. Infusion of GAT1-saporin into the medial septum/vertical limb of the diagonal band disrupts self-movement cue processing and spares mnemonic function.

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    Köppen, Jenny R; Winter, Shawn S; Stuebing, Sarah L; Cheatwood, Joseph L; Wallace, Douglas G

    2013-09-01

    Degeneration of the septohippocampal system is associated with the progression of Dementia of the Alzheimer's type (DAT). Impairments in mnemonic function and spatial orientation become more severe as DAT progresses. Although evidence supports a role for cholinergic function in these impairments, relatively few studies have examined the contribution of the septohippocampal GABAergic component to mnemonic function or spatial orientation. The current study uses the rat food-hoarding paradigm and water maze tasks to characterize the mnemonic and spatial impairments associated with infusing GAT1-Saporin into the medial septum/vertical limb of the diagonal band (MS/VDB). Although infusion of GAT1-Saporin significantly reduced parvalbumin-positive cells in the MS/VDB, no reductions in markers of cholinergic function were observed in the hippocampus. In general, performance was spared during spatial tasks that provided access to environmental cues. In contrast, GAT1-Saporin rats did not accurately carry the food pellet to the refuge during the dark probe. These observations are consistent with infusion of GAT1-Saporin into the MS/VDB resulting in spared mnemonic function and use of environmental cues; however, self-movement cue processing was compromised. This interpretation is consistent with a growing literature demonstrating a role for the septohippocampal system in self-movement cue processing.

  9. Effects of nicotine stimulation on spikes, theta frequency oscillations, and spike-theta oscillation relationship in rat medial septum diagonal band Broca slices

    Institute of Scientific and Technical Information of China (English)

    Dong WEN; Ce PENG; Gao-xiang OU-YANG; Zainab HENDERSON; Xiao-li LI; Cheng-biao LU

    2013-01-01

    Aim:Spiking activities and neuronal network oscillations in the theta frequency range have been found in many cortical areas during information processing.The aim of this study is to determine whether nicotinic acetylcholine receptors (nAChRs) mediate neuronal network activity in rat medial septum diagonal band Broca (MSDB) slices.Methods:Extracellular field potentials were recorded in the slices using an Axoprobe 1A amplifier.Data analysis was performed offline.Spike sorting and local field potential (LFP) analyses were performed using Spike2 software.The role of spiking activity in the generation of LFP oscillations in the slices was determined by analyzing the phase-time relationship between the spikes and LFP oscillations.Circular statistic analysis based on the Rayleigh test was used to determine the significance of phase relationships between the spikes and LFP oscillations.The timing relationship was examined by quantifying the spike-field coherence (SFC).Results:Application of nicotine (250 nmol/L) induced prominent LFP oscillations in the theta frequency band and both small-and large-amplitude population spiking activity in the slices.These spikes were phase-locked to theta oscillations at specific phases.The Rayleigh test showed a statistically significant relationship in phase-locking between the spikes and theta oscillations.Larger changes in the SFC were observed for large-amplitude spikes,indicating an accurate timing relationship between this type of spike and LFP oscillations.The nicotine-induced spiking activity (large-amplitude population spikes) was suppressed by the nAChR antagonist dihydro-β-erythroidine (0.3 μmol/L).Conclusion:The results demonstrate that large-amplitude spikes are phase-locked to theta oscillations and have a high spike-timing accuracy,which are likely a main contributor to the theta oscillations generated in MSDB during nicotine receptor activation.

  10. Patterns of Direct Projections from the Hippocampus to the Medial Septum-Diagonal Band Complex : Anterograde Tracing with Phaseolus vulgaris Leucoagglutinin Combined with Immunohistochemistry of Choline Acetyltransferase

    NARCIS (Netherlands)

    Gaykema, R.P.A.; Kuil, J. van der; Hersh, L.B.; Luiten, P.G.M.

    1991-01-01

    The projections from the Ammon's horn to the cholinergic cell groups in the medial septal and diagonal band nuclei were investigated with anterograde tracing of Phaseolus vulgaris leucoagglutinin combined with immunocytochemical detection of choline acetyltransferase, in the rat. Tracer injections w

  11. Effects of beta-amyloid protein on M1 and M2 subtypes of muscarinic acetylcholine receptors in the medial septum-diagonal band complex of the rat: relationship with cholinergic, GABAergic, and calcium-binding protein perikarya.

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    González, Iván; Arévalo-Serrano, Juan; Sanz-Anquela, José Miguel; Gonzalo-Ruiz, Alicia

    2007-06-01

    Cortical cholinergic dysfunction has been correlated with the expression and processing of beta-amyloid precursor protein. However, it remains unclear as to how cholinergic dysfunction and beta-amyloid (Abeta) formation and deposition might be related to one another. Since the M1- and M2 subtypes of muscarinic acetylcholine receptors (mAChRs) are considered key molecules that transduce the cholinergic message, the purpose of the present study was to assess the effects of the injected Abeta peptide on the number of M1mAchR- and M2mAChR-immunoreactive cells in the medial septum-diagonal band (MS-nDBB) complex of the rat. Injections of Abeta protein into the retrosplenial cortex resulted in a decrease in M1mAChR and M2mAChR immunoreactivity in the MS-nDBB complex. Quantitative analysis revealed a significant reduction in the number of M1mAChR- and M2mAChR-immunoreactive cells in the medial septum nucleus (MS) and in the horizontal nucleus of the diagonal band of Broca (HDB) as compared to the corresponding hemisphere in control animals and with that seen in the contralateral hemisphere, which corresponds to the PBS-injected side. Co-localization studies showed that the M1mAChR protein is localized in GABA-immunoreactive cells of the MS-nDBB complex, in particular those of the MS nucleus, while M2mAChR protein is localized in both the cholinergic and GABAergic cells. Moreover, GABAergic cells containing M2mAChR are mainly localized in the MS nucleus, while cholinergic cells containing M2mAChR are localized in the MS and the HDB nuclei. Our findings suggest that Abeta induces a reduction in M1mAChR- and M2mAChR-containing cells, which may contribute to impairments of cholinergic and GABAergic transmission in the MS-nDBB complex.

  12. GABAergic Projections from the Medial Septum Selectively Inhibit Interneurons in the Medial Entorhinal Cortex

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    Gonzalez-Sulser, Alfredo; Parthier, Daniel; Candela, Antonio; McClure, Christina; Pastoll, Hugh; Garden, Derek; Sürmeli, Gülşen

    2014-01-01

    The medial septum (MS) is required for theta rhythmic oscillations and grid cell firing in the medial entorhinal cortex (MEC). While GABAergic, glutamatergic, and cholinergic neurons project from the MS to the MEC, their synaptic targets are unknown. To investigate whether MS neurons innervate specific layers and cell types in the MEC, we expressed channelrhodopsin-2 in mouse MS neurons and used patch-clamp recording in brain slices to determine the response to light activation of identified cells in the MEC. Following activation of MS axons, we observed fast monosynaptic GABAergic IPSPs in the majority (>60%) of fast-spiking (FS) and low-threshold-spiking (LTS) interneurons in all layers of the MEC, but in only 1.5% of nonstellate principal cells (NSPCs) and in no stellate cells. We also observed fast glutamatergic responses to MS activation in a minority (<5%) of NSPCs, FS, and LTS interneurons. During stimulation of MS inputs at theta frequency (10 Hz), the amplitude of GABAergic IPSPs was maintained, and spike output from LTS and FS interneurons was entrained at low (25–60 Hz) and high (60–180 Hz) gamma frequencies, respectively. By demonstrating cell type-specific targeting of the GABAergic projection from the MS to the MEC, our results support the idea that the MS controls theta frequency activity in the MEC through coordination of inhibitory circuits. PMID:25505326

  13. Forebrain medial septum region facilitates nociception in a rat formalin model of inflammatory pain.

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    Lee, Andy Thiam-Huat; Ariffin, Mohammed Zacky; Zhou, Mingyi; Ye, Jenn Zhou; Moochhala, Shabbir M; Khanna, Sanjay

    2011-11-01

    The medial septum is anatomically and functionally linked to the hippocampus, a region implicated in nociception. However, the role of medial septum in nociception remains unclear. To investigate the role of the region in nociception in rats, muscimol, a GABA agonist, or zolpidem, a positive allosteric modulator of GABA(A) receptors, was microinjected into medial septum to attenuate the activity of neurons in the region. Electrophysiological studies in anesthetized rats indicated that muscimol evoked a stronger and longer-lasting suppression of medial septal-mediated activation of hippocampal theta field activity than zolpidem. Similarly, microinjection of muscimol (1 or 2 μg/0.5 μl) into the medial septum of awake rats suppressed both licking and flinching behaviors in the formalin test of inflammatory pain, whereas only the latter behavior was affected by zolpidem (8 or 12 μg/0.5 μl) administered into the medial septum. Interestingly, both drugs selectively attenuated nociceptive behaviors in the second phase of the formalin test that are partly driven by central plasticity. Indeed, muscimol reduced the second phase behaviors by 30% to 60%, which was comparable to the reduction seen with systemic administration of a moderate dose of the analgesic morphine. The reduction was accompanied by a decrease in formalin-induced expression of spinal c-Fos protein that serves as an index of spinal nociceptive processing. The drug effects on nociceptive behaviors were without overt sedation and were distinct from the effects observed after septal lateral microinjections. Taken together, these findings suggest that the activation of medial septum is pro-nociceptive and facilitates aspects of central neural processing underlying nociception.

  14. The role of NMDA receptors of the medial septum and dorsal hippocampus on memory acquisition.

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    Khakpai, Fatemeh; Nasehi, Mohammad; Zarrindast, Mohammad-Reza

    2016-04-01

    The glutamatergic neurons in the medial septal/diagonal band of broca (MS/DB) affect the hippocampal functions by modulating the septo-hippocampal neurons. Our study investigated the possible role of NMDA receptors of the medial septum nucleus (MS) and dorsal hippocampus (CA1) on memory acquisition in male Wistar rats. Animals were bilaterally implanted with chronic cannulae in the MS and CA1. Rats were trained in a step-through type inhibitory avoidance task, and tested 24h after training to measure step-through latency as memory retrieval. Our results indicated that pre-training intra-MS or intra-CA1 infusions of NMDA (0.125 μg/rat) and D-AP7 (0.012 μg/rat) increased and decreased memory acquisition, respectively when compared to saline control group. Also, pre-training intra-CA1 and intra-MS injection of an effect dose of D-AP7 (0.012 μg/rat) along with an effect dose of NMDA (0.125 μg/rat) impaired memory acquisition. Interestingly, pre-training intra-CA1/MS infusion of D-AP7 (0.012 μg/rat) diminished memory response produced by pre-training injection of NMDA (0.125 μg/rat) in the MS/CA1, respectively (cross injection or bilateral injection). Also, all above doses of drugs did not alter locomotor activity. These results suggest that the glutamatergic pathway between the MS and CA1 regions is involved in memory acquisition process.

  15. Interneurons are the local targets of hippocampal inhibitory cells which project to the medial septum.

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    Gulyás, A I; Hájos, N; Katona, I; Freund, T F

    2003-05-01

    A subset of GABAergic neurons projecting to the medial septum has long been described in the hippocampus. However, the lack of information about their local connectivity pattern or their correspondence with any of the well-established hippocampal interneuron types has hampered the understanding of their functional role. Retrograde tracing combined with immunostaining for neurochemical markers in the adult rat hippocampus showed that nearly all hippocampo-septal (HS) neurons express somatostatin (>95%) and, in the hilus and CA3 stratum lucidum, many contain calretinin (>45%). In contrast, in stratum oriens of the CA1 and CA3 subfields, the majority of HS neurons contain somatostatin (>86%) and calbindin (>73%), but not calretinin. Because somatostatin-positive hippocampal interneurons have been most extensively characterized in the stratum oriens of CA1, we focused our further analysis on HS cells found in this region. In 18-20-day-old rats, intracellularly filled CA1-HS cells had extensive local axon collaterals crossing subfield boundaries and innervating the CA3 region and the dentate gyrus. Electron microscopic analysis provided evidence that the axon terminals of CA1-HS cells form symmetrical synapses selectively on GABAergic interneurons, both locally and in the CA3 region. In addition, double retrograde labelling experiments revealed that many CA1-HS neurons of the dorsal hippocampus also have collateral projections to the ventral hippocampus. Thus, CA1-HS cells innervate inhibitory interneurons locally and in remote hippocampal regions, in addition to targeting mostly GABAergic neurons in the medial septum. This dual projection with striking target selectivity for GABAergic neurons may be ideally suited to synchronize neuronal activity along the septo-hippocampal axis.

  16. Melanin concentrating hormone induces hippocampal acetylcholine release via the medial septum in rats.

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    Lu, Zhi-Hong; Fukuda, Satoru; Minakawa, Yoichi; Yasuda, Atsushi; Sakamoto, Hidetoshi; Sawamura, Shigehito; Takahashi, Hidenori; Ishii, Noriko

    2013-06-01

    Among various actions of melanin concentrating hormone (MCH), its memory function has been focused in animal studies. Although MCH neurons project to various areas in the brain, one main target site of MCH is hippocampal formation for memory consolidation. Recent immunohistochemical study shows that MCH neurons directly project to the hippocampal formation and may indirectly affect the hippocampus through the medial septum nucleus (MS). It has been reported that sleep is necessary for memory and that hippocampal acetylcholine (ACh) release is indispensable for memory consolidation. However, there is no report how MCH actually influences the hippocampal ACh effluxes in accordance with the sleep-wake cycle changes. Thus, we investigated the modulatory function of intracerebroventricular (icv) injection of MCH on the sleep-wake cycle and ACh release using microdialysis techniques. Icv injection of MCH significantly increased the rapid eye movement (REM) and non-REM episode time and the hippocampal, not cortical, ACh effluxes. There was a significant correlation between REM episode time and hippocampal ACh effluxes, but not between REM episode time and cortical ACh effluxes. Microinjection of MCH into the MS increased the hippocampal ACh effluxes with no influence on the REM episode time. It appears that the effect sites of icv MCH for prolongation of REM episode time may be other neuronal areas than the cholinergic neurons in the MS. We conclude that MCH actually increases the hippocampal ACh release at least in part through the MS in rats.

  17. Nicotine induction of theta frequency oscillations in rodent medial septal diagonal band in vitro

    Institute of Scientific and Technical Information of China (English)

    Cheng-biao LU; Cheng-zhang LI; Dong-liang LI; Zaineb HENDERSON

    2013-01-01

    Aim:This study aimed to examine the role of the nicotinic receptor (nAChR) in the generation of theta oscillations (4-12 Hz) in vitro.Methods:Electrophysiological studies were performed on medial septal diagonal band area (MSDB) slices to measure theta oscillation.Immunofluorescence and confocal microscopy studies were carried out to detect α4 nAChR and β2 nAChR subunits in perfused-fixed tissue from VGluT2-GFP and GAD67-GFP transgenic mice.Results:Application of nicotine to MSDB slices produced persistent theta oscillations in which area power increased in a doseresponsive manner.This activity was inhibited by GABAA receptor antagonists and partially by ionotropic glutamate receptor antagonists,indicating the involvement of local GABAergic and glutamatergic neurons in the production of the rhythmic activity.The nicotineinduced theta activity was also inhibited selectively by non-α7*nAChR antagonists,suggesting the presence of these receptor types on GABAergic and glutamatergic neuron populatjons in the MSDB.This was confirmed by immunofluorescence and confocal microscopy studies in transgenic mice in which the GABAergic and glutamatergic neurons express green fluorescent protein (GFP),showing Iocalisation of β2 nAChR and α4 nAChR subunits,the most common constituents of non-α7*nAChRs,in both cell types in the MSDB.Conclusion:Theta activity in the MSDB may be generated by tonic stimulation of non-α7*nAChRs.

  18. OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum

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    Renée V. Hoch

    2015-07-01

    Full Text Available The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO mice to investigate its roles in telencephalon development after neurulation (approximately embryonic day 9.0. We conducted transcriptional profiling and in situ hybridization to identify genes de-regulated in Otx2 cKO ventral forebrain. In parallel, we used chromatin immunoprecipitation sequencing to identify enhancer elements, the OTX2 binding motif, and de-regulated genes that are likely direct targets of OTX2 transcriptional regulation. We found that Otx2 was essential in septum specification, regulation of Fgf signaling in the rostral telencephalon, and medial ganglionic eminence (MGE patterning, neurogenesis, and oligodendrogenesis. Within the MGE, Otx2 was required for ventral, but not dorsal, identity, thus controlling the production of specific MGE derivatives.

  19. Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.

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    Hélène Hall

    Full Text Available Intraneuronal inclusions containing alpha-synuclein (a-syn constitute one of the pathological hallmarks of Parkinson's disease (PD and are accompanied by severe neurodegeneration of A9 dopaminergic neurons located in the substantia nigra. Although to a lesser extent, A10 dopaminergic neurons are also affected. Neurodegeneration of other neuronal populations, such as the cholinergic, serotonergic and noradrenergic cell groups, has also been documented in PD patients. Studies in human post-mortem PD brains and in rodent models suggest that deficits in cholinergic and dopaminergic systems may be associated with the cognitive impairment seen in this disease. Here, we investigated the consequences of targeted overexpression of a-syn in the mesocorticolimbic dopaminergic and septohippocampal cholinergic pathways. Rats were injected with recombinant adeno-associated viral vectors encoding for either human wild-type a-syn or green fluorescent protein (GFP in the ventral tegmental area and the medial septum/vertical limb of the diagonal band of Broca, two regions rich in dopaminergic and cholinergic neurons, respectively. Histopathological analysis showed widespread insoluble a-syn positive inclusions in all major projections areas of the targeted nuclei, including the hippocampus, neocortex, nucleus accumbens and anteromedial striatum. In addition, the rats overexpressing human a-syn displayed an abnormal locomotor response to apomorphine injection and exhibited spatial learning and memory deficits in the Morris water maze task, in the absence of obvious spontaneous locomotor impairment. As losses in dopaminergic and cholinergic immunoreactivity in both the GFP and a-syn expressing animals were mild-to-moderate and did not differ from each other, the behavioral impairments seen in the a-syn overexpressing animals appear to be determined by the long term persisting neuropathology in the surviving neurons rather than by neurodegeneration.

  20. Effective Modulation of Male Aggression through Lateral Septum to Medial Hypothalamus Projection.

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    Wong, Li Chin; Wang, Li; D'Amour, James A; Yumita, Tomohiro; Chen, Genghe; Yamaguchi, Takashi; Chang, Brian C; Bernstein, Hannah; You, Xuedi; Feng, James E; Froemke, Robert C; Lin, Dayu

    2016-03-07

    Aggression is a prevalent behavior in the animal kingdom that is used to settle competition for limited resources. Given the high risk associated with fighting, the central nervous system has evolved an active mechanism to modulate its expression. Lesioning the lateral septum (LS) is known to cause "septal rage," a phenotype characterized by a dramatic increase in the frequency of attacks. To understand the circuit mechanism of LS-mediated modulation of aggression, we examined the influence of LS input on the cells in and around the ventrolateral part of the ventromedial hypothalamus (VMHvl)-a region required for male mouse aggression. We found that the inputs from the LS inhibited the attack-excited cells but surprisingly increased the overall activity of attack-inhibited cells. Furthermore, optogenetic activation of the projection from LS cells to the VMHvl terminated ongoing attacks immediately but had little effect on mounting. Thus, LS projection to the ventromedial hypothalamic area represents an effective pathway for suppressing male aggression.

  1. Improvements in Memory after Medial Septum Stimulation Are Associated with Changes in Hippocampal Cholinergic Activity and Neurogenesis

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    Da Un Jeong

    2014-01-01

    Full Text Available Deep brain stimulation (DBS has been found to have therapeutic effects in patients with dementia, but DBS mechanisms remain elusive. To provide evidence for the effectiveness of DBS as a treatment for dementia, we performed DBS in a rat model of dementia with intracerebroventricular administration of 192 IgG-saporins. We utilized four groups of rats, group 1, unlesioned control; group 2, cholinergic lesion; group 3, cholinergic lesion plus medial septum (MS electrode implantation (sham stimulation; group 4, cholinergic lesions plus MS electrode implantation and stimulation. During the probe test in the water maze, performance of the lesion group decreased for measures of time spent and the number of swim crossings over the previous platform location. Interestingly, the stimulation group showed an equivalent performance to the normal group on all measures. And these are partially reversed by the electrode implantation. Acetylcholinesterase activity in the hippocampus was decreased in lesion and implantation groups, whereas activity in the stimulation group was not different from the normal group. Hippocampal neurogenesis was increased in the stimulation group. Our results revealed that DBS of MS restores spatial memory after damage to cholinergic neurons. This effect is associated with an increase in hippocampal cholinergic activity and neurogenesis.

  2. Theta-rhythmic drive between medial septum and hippocampus in slow-wave sleep and microarousal: a Granger causality analysis

    Science.gov (United States)

    Kang, D.; Ding, M.; Topchiy, I.; Shifflett, L.

    2015-01-01

    Medial septum (MS) plays a critical role in controlling the electrical activity of the hippocampus (HIPP). In particular, theta-rhythmic burst firing of MS neurons is thought to drive lasting HIPP theta oscillations in rats during waking motor activity and REM sleep. Less is known about MS-HIPP interactions in nontheta states such as non-REM sleep, in which HIPP theta oscillations are absent but theta-rhythmic burst firing in subsets of MS neurons is preserved. The present study used Granger causality (GC) to examine the interaction patterns between MS and HIPP in slow-wave sleep (SWS, a nontheta state) and during its short interruptions called microarousals (a transient theta state). We found that during SWS, while GC revealed a unidirectional MS→HIPP influence over a wide frequency band (2–12 Hz, maximum: ∼8 Hz), there was no theta peak in the hippocampal power spectra, indicating a lack of theta activity in HIPP. In contrast, during microarousals, theta peaks were seen in both MS and HIPP power spectra and were accompanied by bidirectional GC with MS→HIPP and HIPP→MS theta drives being of equal magnitude. Thus GC in a nontheta state (SWS) vs. a theta state (microarousal) primarily differed in the level of HIPP→MS. The present findings suggest a modification of our understanding of the role of MS as the theta generator in two regards. First, a MS→HIPP theta drive does not necessarily induce theta field oscillations in the hippocampus, as found in SWS. Second, HIPP theta oscillations entail bidirectional theta-rhythmic interactions between MS and HIPP. PMID:26354315

  3. Influence of ginsenoside on expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in the medial septum of aged rats

    Institute of Scientific and Technical Information of China (English)

    Liang Zeng; Haihua Zhao; Yongli Lü; Wenbo Dai

    2008-01-01

    BACKGROUND: It has been shown that ginsenoside, the effective component of ginseng, can enhance expression of choline acetyl transferase, as well as brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase B (TrkB), in cholinergic neurons of the basal forebrain.OBJECTIVE: To qualitatively and quantitatively verify the influence of ginsenoside on expression of BDNF and its receptor, TrkB, in the medial septum of aged rats, and to provide a molecular basis for clinical application.DESIGN, TIME AND SETTING: A contrast study, which was performed in the Department of Anatomy, China Medical University, and the Department of Anatomy, Shenyang Medical College between December 2005 and May 2007.MATERIALS: Thirty-five, healthy, female, Sprague Dawley rats were selected for this study. Ginsenoside (81% purity) was provided by Jilin Ji'an Wantai Chinese Medicine Factory; anti-BDNF antibody, anti-TrkB antibody, and their kits were provided by Wuhan Boster Company.METHODS: A total of 35 rats were divided into three groups: young (four months old), aging (26 months old), and ginsenoside. Rats in the ginsenoside group were administered ginsenoside (25mg/kg/d) between 17 months and 26 months.MAIN OUTCOME MEASURES: Immunohistochemistry and in situ hybridization were used to measure expression of BDNF and TrkB in the medial septum of aged rats, and the detected results were expressed as gray values.RESULTS: ①Qualitative detection: using microscopy, degenerative neurons were visible in the medial septum in the aging group. However, neuronal morphology in the ginsenoside group was similar to neurons in the young group.②Quantitative detection: the mean gray value of BDNF-positive and TrkB-positive products in the aging group were significantly higher than in the young group (t=3.346,4.169, P<0.01); however, the mean gray value in the ginsenoside group was significantly lower than in the aging group (t=2.432,2.651, P<0.01).CONCLUSION: Ginsenoside can increase

  4. How reduction of theta rhythm by medial septum inactivation may covary with disruption of entorhinal grid cell responses due to reduced cholinergic transmission

    Directory of Open Access Journals (Sweden)

    Praveen K. Pilly

    2013-10-01

    Full Text Available Oscillations in the coordinated firing of brain neurons have been proposed to play important roles in perception, cognition, attention, learning, navigation, and sensory-motor control. The network theta rhythm has been associated with properties of spatial navigation, as has the firing of entorhinal grid cells and hippocampal place cells. Two recent studies reduced the theta rhythm by inactivating the medial septum (MS and demonstrated a correlated reduction in the characteristic hexagonal spatial firing patterns of grid cells. These results, along with properties of intrinsic membrane potential oscillations (MPOs in slice preparations of entorhinal cells, have been interpreted to support oscillatory interference models of grid cell firing. The current article shows that an alternative self-organizing map model of grid cells can explain these data about intrinsic and network oscillations without invoking oscillatory interference. In particular, the adverse effects of MS inactivation on grid cells can be understood in terms of how the concomitant reduction in cholinergic inputs may increase the conductances of leak potassium (K+ and slow and medium after-hyperpolarization (sAHP and mAHP channels. This alternative model can also explain data that are problematic for oscillatory interference models, including how knockout of the HCN1 gene in mice, which flattens the dorsoventral gradient in MPO frequency and resonance frequency, does not affect the development of the grid cell dorsoventral gradient of spatial scales, and how hexagonal grid firing fields in bats can occur even in the absence of theta band modulation. These results demonstrate how models of grid cell self-organization can provide new insights into the relationship between brain learning, oscillatory dynamics, and navigational behaviors.

  5. 保留乳腺横膈内上蒂垂直切口瘢痕乳房缩小术%Vertical incision scar reduction mammaplasty with medial-superior pedicle based on Würinger's horizontal septum

    Institute of Scientific and Technical Information of China (English)

    亓发芝; 张勇; 冯自豪; 顾建英

    2014-01-01

    Objective The vertical mammaplasty improves the breast morphology,and reduces the operative scar.However,the nipple-and-areola complex (NAC) has the risk of necrosis on those severe patients.In this report,we performed the vertical incision scar reduction mammaplasty based on Würinger's horizontal septum to reduce the NAC necrosis possibility.Methods Typical Lejour mosque-dome design was performed.The inferior part of glandular tissue and skin were excised.The NAC was elevated to normal position with medial-superior pedicle based on the horizontal septum.The breast morphology was modified with lateral and medial glandular pillar suturing using nonabsorbent thread.For reducing the vertical scar,the lower breast flap was thinned to induce the skin contraction.Results 27 patients with breast hypertrophy were operated from May 2009 to October 2012.1 patient had unilateral breast reduction,and 6 patients with 8 breasts had partial wound dehiscence.They were treated conservatively with topical dressings.No complete NAC necrosis occurred.Conclusions The vertical reduction mammaplasty based on Würinger's horizontal septum is a safe and effective approach,and the NAC necrosis possibility is reduced with this procedure.%目的 探讨保留乳腺横膈内上蒂垂直切口瘢痕乳房缩小术的临床效果.方法 采用Lejour穹窿顶式手术设计,切除乳房下方多余的皮肤、腺体,将乳头和乳晕以内上方真皮、腺体组织蒂抬高到正常位置,术中保护乳腺中隔神经、血管蒂.采用不吸收缝线缝合乳房下极腺体,适度修薄乳房下部皮肤,以便于皮肤回缩,减轻瘢痕.结果 共行手术27例,53侧乳房,其中1例为单侧乳房缩小术,手术效果满意,乳房形态良好.术后6例8侧乳房切口部分裂开,均经换药后愈合,无1例发生乳头、乳晕坏死.结论 保留乳腺横膈的内上蒂垂直切口瘢痕巨乳缩小术效果良好,提高了乳头、乳晕移位的安全性.

  6. Maternal aggression in Wistar rats: effect of 5-HT2A/2C receptor agonist and antagonist microinjected into the dorsal periaqueductal gray matter and medial septum

    Directory of Open Access Journals (Sweden)

    Almeida R.M.M. de

    2005-01-01

    Full Text Available The objective of the present study was to assess the role of the 5-HT2A/2C receptor at two specific brain sites, i.e., the dorsal periaqueductal gray matter (DPAG and the medial septal (MS area, in maternal aggressive behavior after the microinjection of either a 5-HT2A/2C receptor agonist or antagonist. Female Wistar rats were microinjected on the 7th postpartum day with the selective agonist alpha-methyl-5-hydroxytryptamine maleate (5-HT2A/2C or the antagonist 5-HT2A/2C, ketanserin. The agonist was injected into the DPAG at 0.2 (N = 9, 0.5 (N = 10, and 1.0 µg/0.2 µl (N = 9, and the antagonist was injected at 1.0 µg/0.2 µl (N = 9. The agonist was injected into the medial septal area (MS at 0.2 (N = 9, 0.5 (N = 7, and 1.0 µg/0.2 µl (N = 6 and the antagonist was injected at 1.0 µg/0.2 µl (N = 5. For the control, saline was injected into the DPAG (N = 7 and the MS (N = 12. Both areas are related to aggressive behavior and contain a high density of 5-HT receptors. Non-aggressive behaviors such as horizontal locomotion (walking and social investigation and aggressive behaviors such as lateral threat (aggressive posture, attacks (frontal and lateral, and biting the intruder were analyzed when a male intruder was placed into the female resident's cage. For each brain area studied, the frequency of the behaviors was compared among the various treatments by analysis of variance. The results showed a decrease in maternal aggressive behavior (number of bites directed at the intruder after microinjection of the agonist at 0.2 and 1.0 µg/0.2 µl (1.6 ± 0.7 and 0.9 ± 0.3 into the DPAG compared to the saline group (5.5 ± 1.1. There was no dose-response relationship with the agonist. The present findings suggest that the 5-HT2A/2C receptor agonist has an inhibitory effect on maternal aggressive behavior when microinjected into the DPAG and no effect when microinjected into the MS. Ketanserin (1.0 µg/0.2 µl decreased locomotion when microinjected

  7. Synaptic Targets of Medial Septal Projections in the Hippocampus and Extrahippocampal Cortices of the Mouse.

    Science.gov (United States)

    Unal, Gunes; Joshi, Abhilasha; Viney, Tim J; Kis, Viktor; Somogyi, Peter

    2015-12-02

    Temporal coordination of neuronal assemblies among cortical areas is essential for behavioral performance. GABAergic projections from the medial septum and diagonal band complex exclusively innervate GABAergic interneurons in the rat hippocampus, contributing to the coordination of neuronal activity, including the generation of theta oscillations. Much less is known about the synaptic target neurons outside the hippocampus. To reveal the contribution of synaptic circuits involving the medial septum of mice, we have identified postsynaptic cortical neurons in wild-type and parvalbumin-Cre knock-in mice. Anterograde axonal tracing from the septum revealed extensive innervation of the hippocampus as well as the subiculum, presubiculum, parasubiculum, the medial and lateral entorhinal cortices, and the retrosplenial cortex. In all examined cortical regions, many septal GABAergic boutons were in close apposition to somata or dendrites immunopositive for interneuron cell-type molecular markers, such as parvalbumin, calbindin, calretinin, N-terminal EF-hand calcium-binding protein 1, cholecystokinin, reelin, or a combination of these molecules. Electron microscopic observations revealed septal boutons forming axosomatic or axodendritic type II synapses. In the CA1 region of hippocampus, septal GABAergic projections exclusively targeted interneurons. In the retrosplenial cortex, 93% of identified postsynaptic targets belonged to interneurons and the rest to pyramidal cells. These results suggest that the GABAergic innervation from the medial septum and diagonal band complex contributes to temporal coordination of neuronal activity via several types of cortical GABAergic interneurons in both hippocampal and extrahippocampal cortices. Oscillatory septal neuronal firing at delta, theta, and gamma frequencies may phase interneuron activity.

  8. A New Septum in the Female Breast

    Science.gov (United States)

    Awad, Mostafa Abdel Rahman; Sherif, Mahmoud Magdi; Sadek, Eaman Yahya; Hamid, Wafaa Raafat Abdel

    2017-01-01

    Background Understanding the female breast fascial system is of paramount importance in breast surgery. Little was written about breast ligaments. Most articles refer to Cooper's work without further anatomical studies. Lately, a horizontal septum has been described conveying nerves and vessels to the nipple areola complex. Methods During the surgical dissection of the lower part of the breast, in supero-medial technique for breast reduction operations, a fascial septum between the lower two quadrants was detected. This fibrous septum was studied through anatomic dissection of breast tissues during routine breast reshaping procedures that was done on 30 female patients. Magnetic resonance imaging (MRI) was performed preoperatively in all cases and correlated with the intraoperative findings. In the other five cases, outside the clinical study, the imaging was done during routine investigation for breast swellings. Results A vertical septum was identified in the lower part of the breast, lying at the breast meridian between the two lower quadrants. It is a tough bi-laminated structure that extends from the middle of the infra-mammary crease caudally to nipple-areola complex cranially and from the pectoral fascia posteriorly to the overlying skin anteriorly. This was proved by MRI findings. Conclusions This study describes a new inferior vertical septum which separates the lower half of the breast into two definite anatomical compartments: medial and lateral. PMID:28352598

  9. Electrostatic septum, SPS

    CERN Multimedia

    1975-01-01

    To minimize losses during slow extraction towards N- and W-Area, electrostatic septa in long straight section 2 and 6 precede the magnetic septa. The 2 electrode plates, visible at the entrance to the septum, establish a vertical electrical field to remove the ions created by the circulating beam in the residual gas. See 7801286 for such a septum in its tank, and 7501201 for a detailed view of the wire suspension. See also 7501120X.

  10. Optogenetic activation of septal GABAergic afferents entrains neuronal firing in the medial habenula

    Science.gov (United States)

    Choi, Kyuhyun; Lee, Youngin; Lee, Changwoo; Hong, Seokheon; Lee, Soonje; Kang, Shin Jung; Shin, Ki Soon

    2016-01-01

    The medial habenula (MHb) plays an important role in nicotine-related behaviors such as nicotine aversion and withdrawal. The MHb receives GABAergic input from the medial septum/diagonal band of Broca (MS/DB), yet the synaptic mechanism that regulates MHb activity is unclear. GABA (γ -aminobutyric acid) is a major inhibitory neurotransmitter activating both GABAA receptors and GABAB receptors. Depending on intracellular chloride concentration, however, GABAA receptors also function in an excitatory manner. In the absence of various synaptic inputs, we found that MHb neurons displayed spontaneous tonic firing at a rate of about ~4.4 Hz. Optogenetic stimulation of MS/DB inputs to the MHb evoked GABAA receptor-mediated synaptic currents, which produced stimulus-locked neuronal firing. Subsequent delayed yet lasting activation of GABAB receptors attenuated the intrinsic tonic firing. Consequently, septal GABAergic input alone orchestrates both excitatory GABAA and inhibitory GABAB receptors, thereby entraining the firing of MHb neurons. PMID:27703268

  11. Caffeine elicits c-Fos expression in horizontal diagonal band cholinergic neurons.

    Science.gov (United States)

    Reznikov, Leah R; Pasumarthi, Ravi K; Fadel, Jim R

    2009-12-09

    Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on cholinergic neuron activation in the rat basal forebrain. Young adult (age 2 months) male rats were treated with caffeine (0, 10, or 50 mg/kg) and killed 2 h later. Caffeine significantly increased c-Fos expression in cholinergic neurons of the horizontal limb of the diagonal band of Broca but not other basal forebrain regions such as the medial septum or substantia innominata. The horizontal limb of the diagonal band of Broca provides cholinergic innervation to the olfactory bulb, suggesting that deficits in this structure may contribute to diminished olfactory function observed in Alzheimer's disease patients. These results suggest that part of the cognitive-enhancing effects of caffeine may be mediated through activation of this part of the cholinergic basal forebrain.

  12. Electrostatic septum, SPS

    CERN Multimedia

    CERN PhotoLab

    1975-01-01

    To minimize losses during slow extraction towards N- and W-Area, electrostatic septa in long straight sections 2 and 6 precede the magnetic septa. This picture is a detail of 7501199, and shows the suspension of the wires. 7801286 shows a septum in its tank. See also 7501120X.

  13. Electrostatic septum, SPS

    CERN Multimedia

    CERN PhotoLab

    1978-01-01

    To minimize losses during slow extraction towards N- and W-Area, electrostatic septa in long straight sections 2 and 6 precede the magnetic septa. This picture shows such an electrostatic septum in its tank. See 7501120X, 7501199 and 7501201 for more detailed pictures.

  14. Diagonalization of Hamiltonian; Diagonalization of Hamiltonian

    Energy Technology Data Exchange (ETDEWEB)

    Garrido, L. M.; Pascual, P.

    1960-07-01

    We present a general method to diagonalized the Hamiltonian of particles of arbitrary spin. In particular we study the cases of spin 0,1/2, 1 and see that for spin 1/2 our transformation agrees with Foldy's and obtain the expression for different observables for particles of spin C and 1 in the new representation. (Author) 7 refs.

  15. Electrostatic septum, SPS

    CERN Multimedia

    1975-01-01

    To minimize losses during slow extraction towards N- and W-Areas, electrostatic septa in long straight sections 2 an 6 precede the magnetic septa. The 2 electrode plates, visible at the entrance to the septum, provide a vertical electric field to remove the ions created by the circulating beam in the residual gas. Here we see one of the electrostatic septa being assembled by Faustin Emery (left) and Jacques Soubeyran (right), in the clean room of building 867. See also 7501199, 7501201, 7801286 and further explanations there.

  16. Nasal septum extramedullary plasmacytoma

    Directory of Open Access Journals (Sweden)

    Belić Branislav

    2013-01-01

    Full Text Available Introduction. Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone - solitary osseous plasmacytoma, or in soft tissue - extramedullary plasmacytoma (EMP. EMP represents less than 1% of all head and neck malignancies. Case report. We presented a case of EMP of the nasal septum in a 44-year-old male who had progressive difficulty in breathing through the nose and frequent heavy epistaxis on the right side. Nasal endoscopy showed dark red, soft, polypoid tumor in the last third of the right nasal cavity arising from the nasal septum. The biopsy showed that it was plasmacytoma. Bence Jones protein in the urine, serum electrophoresis, bone marrow biopsy, skeletal survey and other screening tests failed to detect multiple myeloma. This confirmed the diagnosis of EMP. The mass was completely removed via an endoscopic approach, and then, 4 week later, radiotherapy was conducted with a radiation dose of 50 Gray. No recurrence was noted in a 3-year follow- up period. Conclusion. EMP of the nasal cavity, being rare and having long natural history, represents a diagnostic and therapeutic challenge for any ear, nose and throat surgeon. Depending on the resectability of the lesion, a combined therapy is the accepted treatment.

  17. Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area.

    Science.gov (United States)

    Puelles, Luis; Morales-Delgado, N; Merchán, P; Castro-Robles, B; Martínez-de-la-Torre, M; Díaz, C; Ferran, J L

    2016-07-01

    The telencephalic subpallium is the source of various GABAergic interneuron cohorts that invade the pallium via tangential migration. Based on genoarchitectonic studies, the subpallium has been subdivided into four major domains: striatum, pallidum, diagonal area and preoptic area (Puelles et al. 2013; Allen Developing Mouse Brain Atlas), and a larger set of molecularly distinct progenitor areas (Flames et al. 2007). Fate mapping, genetic lineage-tracing studies, and other approaches have suggested that each subpallial subdivision produces specific sorts of inhibitory interneurons, distinguished by differential peptidic content, which are distributed tangentially to pallial and subpallial target territories (e.g., olfactory bulb, isocortex, hippocampus, pallial and subpallial amygdala, striatum, pallidum, septum). In this report, we map descriptively the early differentiation and apparent migratory dispersion of mouse subpallial somatostatin-expressing (Sst) cells from E10.5 onward, comparing their topography with the expression patterns of the genes Dlx5, Gbx2, Lhx7-8, Nkx2.1, Nkx5.1 (Hmx3), and Shh, which variously label parts of the subpallium. Whereas some experimental results suggest that Sst cells are pallidal, our data reveal that many, if not most, telencephalic Sst cells derive from de diagonal area (Dg). Sst-positive cells initially only present at the embryonic Dg selectively populate radially the medial part of the bed nucleus striae terminalis (from paraseptal to amygdaloid regions) and part of the central amygdala; they also invade tangentially the striatum, while eschewing the globus pallidum and the preoptic area, and integrate within most cortical and nuclear pallial areas between E10.5 and E16.5.

  18. Chaotic diagonal recurrent neural network

    Institute of Scientific and Technical Information of China (English)

    Wang Xing-Yuan; Zhang Yi

    2012-01-01

    We propose a novel neural network based on a diagonal recurrent neural network and chaos,and its structure andlearning algorithm are designed.The multilayer feedforward neural network,diagonal recurrent neural network,and chaotic diagonal recurrent neural network are used to approach the cubic symmetry map.The simulation results show that the approximation capability of the chaotic diagonal recurrent neural network is better than the other two neural networks.

  19. The diagonalization of cubic matrices

    Science.gov (United States)

    Cocolicchio, D.; Viggiano, M.

    2000-08-01

    This paper is devoted to analysing the problem of the diagonalization of cubic matrices. We extend the familiar algebraic approach which is based on the Cardano formulae. We rewrite the complex roots of the associated resolvent secular equation in terms of transcendental functions and we derive the diagonalizing matrix.

  20. The caudal septum replacement graft.

    Science.gov (United States)

    Foda, Hossam M T

    2008-01-01

    To describe a technique for reconstructing the lost tip support in cases involving caudal septal and premaxillary deficiencies. The study included 120 patients with aesthetic and functional nasal problems resulting from the loss of caudal septal and premaxillary support. An external rhinoplasty approach was performed to reconstruct the lost support using a cartilaginous caudal septum replacement graft and premaxillary augmentation with Mersilene mesh. The majority of cases (75%) involved revisions in patients who had previously undergone 1 or more nasal surgical procedures. A caudal septum replacement graft was combined with premaxillary augmentation in 93 patients (77.5%). The mean follow-up period was 3 years (range, 1-12 years). The technique succeeded in correcting the external nasal deformities in all patients and resulted in a significant improvement in breathing in 74 patients (86%) with preoperative nasal obstruction. There were no cases of infection, displacement, or extrusion. The caudal septum replacement graft proved to be very effective in restoring the lost tip support in patients with caudal septal deficiency. Combining the graft with premaxillary augmentation using Mersilene mesh helped increase support and stability over long-term follow-up.

  1. Interventricular septum hematoma during cineventriculography

    Directory of Open Access Journals (Sweden)

    Melzer Christoph

    2008-01-01

    Full Text Available Abstract Background Intraseptal hematoma and subsequent myocardial infarction due to accidental contrast agent deposition complicating diagnostic cineventriculography is a previously undescribed complication of angiography. Case presentation A 61 year old man was admitted at intensive care unit because of unstable angina pectoris 1 hour after coronary angiography. Transthoracic contrast echocardiography showed a non-perfused area in the middle of interventricular septum with an increase of thickening up to 26 mm. Review of cineventriculography revealed contrast enhancement in the interventricular septum after contrast medium injection and a dislocation of the pigtail catheter tip. Follow up by echocardiography and MRI showed, that intramural hematoma has resolved after 6 weeks. After 8 weeks successful stent implantation in LAD was performed and after 6 month the patient had a normal LV-function without ischemic signs or septal thickening demonstrated by stressechocardiography. Conclusion A safe and mobile position of the pigtail catheter during ventriculography in the middle of the LV cavity should be ensured to avoid this potentially life-threatening complication. For assessment and absolute measurement of intramural hematoma contrast-enhanced echocardiography is more feasible than MRI and makes interchangeable results.

  2. Flavor-diagonal CP violation

    Science.gov (United States)

    Batell, Brian

    2012-09-01

    The focus of this brief review is on new physics (NP) sources of CP violation, especially related to the flavor-diagonal phenomena of electric dipole moments (EDMs) of elementary particles and atoms. Using weak scale supersymmetry as an example, we illustrate various aspects of the "new physics CP-problem". We also explore the interplay between flavor-changing and flavor-diagonal CP violation in the context of the recent hints from the Tevatron for new sources of CP violation in the B-meson systems.

  3. Energy Deposition in a Septum Wire

    CERN Document Server

    Ferioli, G; Knaus, P; Koopman, J; CERN. Geneva. SPS and LHC Division

    2001-01-01

    The present note describes a machine development (MD) aimed to confirm experimentally the need for protection of the extraction wire septum ZS in SPS long straight section LSS6 during LHC operation. Single wires identical to the ones mounted on the extraction septum were fixed on a fast wire scanner and put into the beam path. The beam heated the wire until it broke after a measured number of turns. The maximum single shot intensity the septum wires could withstand was thus calculated and compared with simulation results.

  4. Isolated absence of the septum pellucidum

    Energy Technology Data Exchange (ETDEWEB)

    Supprian, T. [Department of Psychiatry, University of Wuerzburg, Fuechsleinstrasse 15, D-97080 Wuerzburg (Germany)]|[Department of Neuroradiology, University of Wuerzburg (Germany); Sian, J.; Heils, A. [Department of Psychiatry, University of Wuerzburg, Fuechsleinstrasse 15, D-97080 Wuerzburg (Germany); Hofmann, E.; Warmuth-Metz, M.; Solymosi, L. [Department of Neuroradiology, University of Wuerzburg (Germany)

    1999-08-01

    Absence of the septum pellucidum in the human is a rare congenital anomaly. Previous reports suggest it is almost always associated with other brain anomalies. However, MRI in two patients with absence of the septum pellucidum presented here, indicates that this anomaly may occur without associated anomalies. It may be one manifestation of a spectrum of developmental anomalies. One patient presented with schizophrenic psychosis; developmental disturbances in limbic areas are believed to be associated with schizophrenia. Agenesis of the septum pellucidum may indicate abnormal development of limbic structures and it may be associated with anomalies, such as cytoarchitectural disturbances of cortical layers, as yet undetectable by MRI. (orig.) With 1 fig., 19 refs.

  5. Spectral diagonal ensemble Kalman filters

    CERN Document Server

    Kasanický, Ivan; Vejmelka, Martin

    2015-01-01

    A new type of ensemble Kalman filter is developed, which is based on replacing the sample covariance in the analysis step by its diagonal in a spectral basis. It is proved that this technique improves the aproximation of the covariance when the covariance itself is diagonal in the spectral basis, as is the case, e.g., for a second-order stationary random field and the Fourier basis. The method is extended by wavelets to the case when the state variables are random fields, which are not spatially homogeneous. Efficient implementations by the fast Fourier transform (FFT) and discrete wavelet transform (DWT) are presented for several types of observations, including high-dimensional data given on a part of the domain, such as radar and satellite images. Computational experiments confirm that the method performs well on the Lorenz 96 problem and the shallow water equations with very small ensembles and over multiple analysis cycles.

  6. Nasal Septum Perforation due to Methamphetamine abuse

    Directory of Open Access Journals (Sweden)

    Mehdi Bakhshaee

    2012-07-01

    Full Text Available Introduction: Spontaneous Perforation of the nasal septum is an uncommon condition. Nasal inhalation of substances such as cocaine has long been linked to this Perforation. Case Report: This report describes the case of a 46-year-old woman who was addicted to methamphetamine and who presented with perforation of the nasal septum.This is the first reported case of nasal septal necrosis linked to nasal inhalation of methamphetamine. Conclusions: Patient history and assurance regardingillegal drug consumption and abuse is a key point for fast and accurate diagnosis. The pathophysiology of drug-induced sinunasal disease and a review of the literature are also presented.

  7. Septum nasal perforation: treatments and literature' review

    Directory of Open Access Journals (Sweden)

    Martinez Neto, Eulógio Emílio

    2010-03-01

    Full Text Available Introduction: The present study consists in a bibliographical' review concerning the articles related to the different manifestations and forms of the septum nasal perforation, with a main emphasis in the description of its techniques of surgical correction. As the etiology, that is fundamentally iatrogenic, accordingly surgical trauma. Other causes include exhibition to chemical industrial reagents, cocaine use, intranasal steroidal therapeutic, neoplasia and, infectious conditions. There is a few data concerning the prevalence of septum perforation in the general population. The decision making about surgical correction or medical treatment depend on the anatomic characteristics and of the pathogenesis of the septal perforation.

  8. Biventricular Mural Endocarditis on the Intraventricular Septum.

    Science.gov (United States)

    Mori, Makoto; Hosoba, Soh; Yoshimura, Stephanie; Lattouf, Omar

    2015-10-28

    Mural endocarditis is an inflammation and disruption of the nonvalvular endocardial surface of the cardiac chambers. We present a rare case of mural endocarditis on the intraventricular (IV) septum on both the left and right ventricular side with intact valvular annulus. This case highlights the complexity of the operative and postoperative management in an unprecedented case of biventricular mural endocarditis.

  9. Pengukuran Sumbatan Hidung pada Deviasi Septum Nasi

    Directory of Open Access Journals (Sweden)

    Bestari J Budiman

    2012-07-01

    Full Text Available Abstrak Latar Belakang: Gejala sumbatan hidung meskipun bukan suatu gejala penyakit yang berat, tetapi dapat menurunkan kualitas hidup dan aktivitas penderita. Penyebab sumbatan hidung dapat bervariasi dari berbagai penyakit dan kelainan anatomis. Salah satu penyebab dari kelainan anatomi adalah deviasi septum nasi. Tujuan: Untuk menilai gejala dan derajat sumbatan hidung pada deviasi septum nasi. Tinjauan Pustaka: Diagnosis dari gejala sumbatan hidung sangat kompleks dan bervariasi, selain berdasarkan anamnesis dan pemeriksaan fisik juga diperlukan pemeriksaan penunjang untuk pengukuran sumbatan hidung. Skor sumbatan hidung merupakan salah satu parameter untuk menilai suatu sumbatan hidung pada deviasi septum nasi. Untuk itu diperlukan pemeriksaan penunjang yang dapat digunakan untuk mendiagnosis dan mengevaluasi gejala sumbatan hidung, diantaranya adalah nasal inspiratory flow meter, rhinomanometri dan rhinometri akustik. Kesimpulan: Gejala sumbatan hidung pada deviasi septum dapat dievaluasi dengan pemeriksaan tambahan meliputi pemeriksaan dengan spatula lidah, nasal inspiratory flow metry, nasal expiratory flow metry, rinomanometri, dan rinometri akustik. Kata kunci: sumbatan hidung, deviasi septum, nasal inspiratory flow metry, nasal expiratory flow metry, rinomanometri, rinometri akuistik. Abstract Background: Although nasal obstruction is not a severe symptom of the disease, it can decrease the quality of life and activity of the patient. The etiology of nasal obstruction could be varied from any diseases and anatomical abnormalities. One of anatomical abnormality cause is septal deviation. Purpose: To evaluate the symptom and the degree of nasal obstruction in septal deviation. Review: The diagnosis of nasal obstruction is more complex and varied, based on anamnesis and physical examination, and beside that need additional examination to measure the nasal patency. Nasal obstruction score is one of parameter to evaluate the obstruction of

  10. A note on generalized nonlinear diagonal dominance

    Science.gov (United States)

    Gan, Tai-Bin; Huang, Ting-Zhu; Gao, Jian

    2006-01-01

    In this paper, an open problem, proposed by A. Frommer, about nonlinear generalized diagonal dominance, is solved on some weak restriction, a counterexample is presented if such a restriction is omitted, and some new properties of nonlinear generalized diagonally dominant functions are investigated.

  11. Simultaneous diagonalization of two quaternion matrices

    Institute of Scientific and Technical Information of China (English)

    ZhouJianhua

    2003-01-01

    The simultaneous diagonalization by congruence of pairs of Hermitian quatemion matrices is discussed. The problem is reduced to a parallel one on complex matrices by using the complex adjoint matrix related to each quatemion matrix. It is proved that any two semi-positive definite Hermitian quatemion matrices can be simultaneously diagonalized by congruence.

  12. PS, septum magnet for ejection of antiprotons

    CERN Multimedia

    1980-01-01

    Antiprotons circulated in the PS in the sense opposite to that of the so far normal protons (or positive ions). A new ejection system with a new septum magnet was installed in straight section 58 for antiproton ejection, first towards the ISR and then to the principal customer, the SPS p-pbar Collider. Later on, when the PS delivered leptons for LEP, the antiproton ejection system was use for the ejection of electrons.

  13. Septum nasal perforation: treatments and literature' review

    OpenAIRE

    Martinez Neto, Eulógio Emílio; Dolci, Luiz Eduardo Lutaif; Murta, Alexandre Antonio; Zanini, Fábio Duro

    2010-01-01

    Introduction: The present study consists in a bibliographical' review concerning the articles related to the different manifestations and forms of the septum nasal perforation, with a main emphasis in the description of its techniques of surgical correction. As the etiology, that is fundamentally iatrogenic, accordingly surgical trauma. Other causes include exhibition to chemical industrial reagents, cocaine use, intranasal steroidal therapeutic, neoplasia and, infectious conditions. There is...

  14. Propagation in Diagonal Anisotropic Chirowaveguides

    Directory of Open Access Journals (Sweden)

    S. Aib

    2017-01-01

    Full Text Available A theoretical study of electromagnetic wave propagation in parallel plate chirowaveguide is presented. The waveguide is filled with a chiral material having diagonal anisotropic constitutive parameters. The propagation characterization in this medium is based on algebraic formulation of Maxwell’s equations combined with the constitutive relations. Three propagation regions are identified: the fast-fast-wave region, the fast-slow-wave region, and the slow-slow-wave region. This paper focuses completely on the propagation in the first region, where the dispersion modal equations are obtained and solved. The cut-off frequencies calculation leads to three cases of the plane wave propagation in anisotropic chiral medium. The particularity of these results is the possibility of controlling the appropriate cut-off frequencies by choosing the adequate physical parameters values. The specificity of this study lies in the bifurcation modes confirmation and the possible contribution to the design of optical devices such as high-pass filters, as well as positive and negative propagation constants. This negative constant is an important feature of metamaterials which shows the phenomena of backward waves. Original results of the biaxial anisotropic chiral metamaterial are obtained and discussed.

  15. A class of Bell diagonal states and entanglement witnesses

    CERN Document Server

    Chruscinski, D; Mlodawski, K; Matsuoka, T

    2010-01-01

    We analyze special class of bipartite states - so called Bell diagonal states. In particular we provide new examples of bound entangled Bell diagonal states and construct the class of entanglement witnesses diagonal in the magic basis.

  16. On triangular algebras with noncommutative diagonals

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    We construct a triangular algebra whose diagonals form a noncommutative algebra and its lattice of invariant projections contains only two nontrivial projections. Moreover we prove that our triangular algebra is maximal.

  17. Diagonal loading least squares time delay estimation

    Institute of Scientific and Technical Information of China (English)

    LI Xuan; YAN Shefeng; MA Xiaochuan

    2012-01-01

    Least squares (LS) time delay estimation is a classical and effective method. However, the performance is degraded severely in the scenario of low ratio of signal-noise (SNR) due to the instability of matrix inversing. In order to solve the problem, diagonal loading least squares (DL-LS) is proposed by adding a positive definite matrix to the inverse matrix. Furthermore, the shortcoming of fixed diagonal loading is analyzed from the point of regularization that when the tolerance of low SNR is increased, veracity is decreased. This problem is resolved by reloading. The primary estimation's reciprocal is introduced as diagonal loading and it leads to small diagonal loading at the time of arrival and larger loading at other time. Simulation and pool experiment prove the algorithm has better performance.

  18. On triangular algebras with noncommutative diagonals

    Institute of Scientific and Technical Information of China (English)

    DONG AiJu

    2008-01-01

    We construct a triangular algebra whose diagonals form a noncommutative algebra and its lattice of invariant projections contains only two nontrivial projections.Moreover we prove that our triangular algebra is maximal.

  19. Diagonal chromatography to study plant protein modifications

    NARCIS (Netherlands)

    Walton, Alan; Tsiatsiani, Liana; Jacques, Silke; Stes, Elisabeth; Messens, Joris; Van Breusegem, Frank; Goormachtig, Sofie; Gevaert, Kris

    2016-01-01

    An interesting asset of diagonal chromatography, which we have introduced for contemporary proteome research, is its high versatility concerning proteomic applications. Indeed, the peptide modification or sorting step that is required between consecutive peptide separations can easily be altered and

  20. Glutamic acid decarboxylase isoform distribution in transgenic mouse septum: an anti-GFP immunofluorescence study.

    Science.gov (United States)

    Verimli, Ural; Sehirli, Umit S

    2016-09-01

    The septum is a basal forebrain region located between the lateral ventricles in rodents. It consists of lateral and medial divisions. Medial septal projections regulate hippocampal theta rhythm whereas lateral septal projections are involved in processes such as affective functions, memory formation, and behavioral responses. Gamma-aminobutyric acidergic neurons of the septal region possess the 65 and 67 isoforms of the enzyme glutamic acid decarboxylase. Although data on the glutamic acid decarboxylase isoform distribution in the septal region generally appears to indicate glutamic acid decarboxylase 67 dominance, different studies have given inconsistent results in this regard. The aim of this study was therefore to obtain information on the distributions of both of these glutamic acid decarboxylase isoforms in the septal region in transgenic mice. Two animal groups of glutamic acid decarboxylase-green fluorescent protein knock-in transgenic mice were utilized in the experiment. Brain sections from the region were taken for anti-green fluorescent protein immunohistochemistry in order to obtain estimated quantitative data on the number of gamma-aminobutyric acidergic neurons. Following the immunohistochemical procedures, the mean numbers of labeled cells in the lateral and medial septal nuclei were obtained for the two isoform groups. Statistical analysis yielded significant results which indicated that the 65 isoform of glutamic acid decarboxylase predominates in both lateral and medial septal nuclei (unpaired two-tailed t-test p glutamic acid decarboxylase isoform 65 in the septal region in glutamic acid decarboxylase-green fluorescent protein transgenic mice.

  1. Compressive and tensile mechanical properties of the porcine nasal septum

    OpenAIRE

    Al Dayeh, Ayman A.; HERRING, SUSAN W.

    2013-01-01

    The expanding nasal septal cartilage is believed to create a force that powers midfacial growth. In addition, the nasal septum is postulated to act as a mechanical strut that prevents the structural collapse of the face under masticatory loads. Both roles imply that the septum is subject to complex biomechanical loads during growth and mastication. The purpose of this study was to measure the mechanical properties of the nasal septum to determine (1) whether the cartilage is mechanically capa...

  2. The injection septum magnets of the SPring-8 storage ring

    Energy Technology Data Exchange (ETDEWEB)

    Kumagai, Keiko; Matsui, Sakuo [JAERI-RIKEN, Hyogo (Japan)

    1994-07-01

    Three DC septum magnets and a pulsed septum magnet are used for the injection of the SPring-8 storage ring. This paper describes the design principle of these injection septum magnets and the electromagnetic performances of a prototype pulsed magnet. The peak strength of the magnetic stray field of the pulsed septum magnet is 1.3 gauss on the bump orbit, and is lower than the limit of sensitivity of the measurement on the reference orbit when the field strength in the magnet gap is 5,600 gauss and the pulse width is 65 {mu}sec.

  3. Reproductive outcome of septate uterus following hysteroscopic septum resection

    Directory of Open Access Journals (Sweden)

    Priya Selvaraj

    2010-01-01

    Full Text Available Objective : To evaluate the reproductive outcome following hysteroscopic septum resection in patients with primary and secondary (recurrent pregnancy loss [RPL] and bad obstetric history [BOH] infertility. Study Design : Retrospective study. Materials and Methods : Hysteroscopic septum resection was performed on 26 patients with a history of either recurrent pregnancy loss, BOH or infertility. The septum resection was performed using a bipolar versapoint system. Reproductive performance of these patients after septum resection was analyzed. The main outcome measures were clinical pregnancy and live birth rates. Results : Hysteroscopic septum resection was performed on seven patients with the history of secondary infertility. Post operatively, the pregnancy rate was 86% (n=6, and the live birth rate was 67% (n=4. After septum resection in 19 primary infertile patients, 6 (32% patients conceived which resulted in live birth rates of 67% (n=4. Conclusion : Hysteroscopic septum resection using bipolar versapoint system is an effective and safe approach for the removal of septum. Hysteroscopic septum resection in women with septate uterus significantly improves the live birth rates and future fertility is not impaired.

  4. DESIGN OF BEAM-EXTRACTION SEPTUM MAGNET FOR THE SNS.

    Energy Technology Data Exchange (ETDEWEB)

    TSOUPAS,N.; LEE,Y.Y.; RANK,J.; TUOZZOLO,J.

    2001-06-18

    The beam-extraction process from the SNS accumulator ring [1,2] requires a Lambertson septum magnet. In this paper we discuss the geometrical and magnetic field requirements of the magnet and present results obtained from two and three dimensional magnetic field calculations that shows the field quality in the regions of interest of the septum magnet.

  5. Septum assessment of the JET gas box divertor

    NARCIS (Netherlands)

    Rapp, J.; Fundamenski, W.; Ingesson, L. C.; Jachmich, S.; Huber, A.; Matthews, G. F.; Morgan, P.; Stamp, M. F.

    2008-01-01

    The influence of the physical isolation of inner and outer divertor volumes by a septum plate of the Mk-II gas box divertor, thus increasing divertor closure and neutral compression, on the plasma and divertor performance has been studied at the Joint European Torus (JET). The septum plate was insta

  6. Endoscopic removal of nasal septum chondrosarcoma in paediatric patient

    Directory of Open Access Journals (Sweden)

    Muhammad Nasri Abu Bakar

    2014-07-01

    We report a boy with progressive history of nasal obstruction and epistaxis. Nasal endoscopy revealed a mass arising from nasal septum. Endoscopic excision of the tumour was successfully done followed by radiotherapy. Endoscopic excision of chondrosarcoma of the nasal septum in its early stage should be considered for better outcome.

  7. Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior

    Directory of Open Access Journals (Sweden)

    Martine M Mirrione

    2014-02-01

    Full Text Available Uncontrollable stress can have a profound effect on an organism’s ability to respond effectively to future stressful situations. Behavior subsequent to uncontrollable stress can vary greatly between individuals, falling on a spectrum between healthy resilience and maladaptive learned helplessness. It is unclear whether dysfunctional brain activity during uncontrollable stress is associated with vulnerability to learned helplessness; therefore, we measured metabolic activity during uncontrollable stress that correlated with ensuing inability to escape future stressors. We took advantage of small animal positron emission tomography (PET and 2-deoxy-2[18F]fluoro-D-glucose (18FDG to probe in vivo metabolic activity in wild type Sprague Dawley rats during uncontrollable, inescapable, unpredictable foot-shock stress, and subsequently tested the animals response to controllable, escapable, predictable foot-shock stress. When we correlated metabolic activity during the uncontrollable stress with consequent behavioral outcomes, we found that the degree to which animals failed to escape the foot-shock correlated with increased metabolic activity in the lateral septum and habenula. When used a seed region, metabolic activity in the habenula correlated with activity in the lateral septum, hypothalamus, medial thalamus, mammillary nuclei, ventral tegmental area, central gray, interpeduncular nuclei, periaqueductal gray, dorsal raphe, and rostromedial tegmental nucleus, caudal linear raphe, and subiculum transition area. Furthermore, the lateral septum correlated with metabolic activity in the preoptic area, medial thalamus, habenula, interpeduncular nuclei, periaqueductal gray, dorsal raphe, and caudal linear raphe. Together, our data suggest a group of brain regions involved in sensitivity to uncontrollable stress involving the lateral septum and habenula.

  8. Diagonal chromatography to study plant protein modifications.

    Science.gov (United States)

    Walton, Alan; Tsiatsiani, Liana; Jacques, Silke; Stes, Elisabeth; Messens, Joris; Van Breusegem, Frank; Goormachtig, Sofie; Gevaert, Kris

    2016-08-01

    An interesting asset of diagonal chromatography, which we have introduced for contemporary proteome research, is its high versatility concerning proteomic applications. Indeed, the peptide modification or sorting step that is required between consecutive peptide separations can easily be altered and thereby allows for the enrichment of specific, though different types of peptides. Here, we focus on the application of diagonal chromatography for the study of modifications of plant proteins. In particular, we show how diagonal chromatography allows for studying proteins processed by proteases, protein ubiquitination, and the oxidation of protein-bound methionines. We discuss the actual sorting steps needed for each of these applications and the obtained results. This article is part of a Special Issue entitled: Plant Proteomics--a bridge between fundamental processes and crop production, edited by Dr. Hans-Peter Mock.

  9. Calculation and optimization of stray fields of septum dipole magnets

    CERN Document Server

    Holmes, Andrew J T

    1976-01-01

    A theoretical treatment is described of the external stray field of C- shaped septum magnets, such as those designed for the beam extraction systems of the 400 GeV CERN Super Proton Synchrotron. A special conformal transformation of the magnetic plane yields analytic expressions for the four components of the stray field: the septum- shape field (due to the form of the septum conductor), the edge-effect field (due to the mechanical clearance between septum and yoke), the cooling-duct field (due to the presence of these ducts in the septum), and the magnetomotance field (caused by the ampere-turn losses in the yoke). These expressions can be computed by numerical iteration. The septum-shape field turns out to be opposite in sign to the other three, making possible a criterion which creates a minimal stray field for a given magnetic induction. Plots of calculated and measured stray fields are presented for four prototype septum magnets whose total induction is between 0.38 and 1.41 T. (3 refs).

  10. Diagonal and off-diagonal quark number susceptibilities at high temperatures

    CERN Document Server

    Ding, H -T; Ohno, H; Petreczky, P; Schadler, H -P

    2015-01-01

    We present continuum extrapolated lattice QCD results for up to fourth order diagonal and off-diagonal quark number susceptibilities in the high temperature region of 300-700 MeV. Lattice QCD calculations are performed using 2+1 flavors of highly improved staggered quarks with nearly physical quark masses and at four different lattice spacings. Comparisons of our results with recent weak coupling perturbative calculations yield reasonably good agreements for the entire temperature range.

  11. Studies and implementation of the PS dummy septum to mitigate irradiation of magnetic septum in straight section 16

    CERN Document Server

    Bertone, C; Bodart, D; Brown, R; Burger, S; Damjanovic, S; Demarest, P; Fernandez Ortega, R; Ferreira Somoza, JA; Gerard, D; Gibson, S; Gilardoni, S; Giovannozzi, M; Le Godec, G; Hernalsteens, C; Hourican, M; Jurado, N; Lacroix, J M; Mataguez, S; Métral, G; Pasquino, C; Perez-Duenas, E; Persichelli, S; Salvant, B; Steerenberg, R; Van Trappen, P

    2014-01-01

    During the commissioning phase of the PS Multi-Turn Extraction (MTE) and the following operational period a number of limitations were observed, namely activation of the magnetic septum in straight section 16, fluctuation of the fraction of particles trapped in the islands, and instabilities of the injection trajectories in the SPS. These issues have been addressed in many ways, by either dedicated measurement campaigns or paper studies to determine mitigation measures. In this document the proposed solution of installing a dummy septum in straight section 15 of the PS ring to reduce the activation of the extraction magnetic septum is described in details.

  12. Optical properties of nasal septum cartilage

    Science.gov (United States)

    Bagratashvili, Nodar V.; Sviridov, Alexander P.; Sobol, Emil N.; Kitai, Moishe S.

    1998-05-01

    Optical parameters (scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g) of hyaline cartilage were studied for the first time. Optical properties of human and pig nasal septum cartilage, and of bovine ear cartilage were examined using a spectrophotometer with an integrating sphere, and an Optical Multi-Channel Analyser. We measured total transmission Tt, total reflection Rt, and on-axis transmission Ta for light propagating through cartilage sample, over the visible spectral range (14000 - 28000 cm-1). It is shown that transmission and reflection spectra of human, pig and bovine cartilage are rather similar. It allows us to conclude that the pig cartilage can be used for in-vivo studies instead of human cartilage. The data obtained were treated by means of the one-dimensional diffusion approximation solution of the optical transport equation. We have found scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g by the iterative comparison of measured and calculated Tt, Rt and Ta values for human and pig cartilage. We found, in particular, that for 500 nm irradiation s equals 37,6 plus or minus 3.5 cm-1, g equals 0,56 plus or minus 0.05, k approximately equals 0,5 plus or minus 0.3 cm-1. The above data were used in Monte Carlo simulation for spatial intensity profile of light scattered by a cartilage sample. The computed profile was very similar to the profile measured using an Optical Multi-Channel Analyzer (OMA).

  13. New Criteria for Judging Generalized Strictly Diagonally Dominant Matrix

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-song

    2015-01-01

    Generalized strictly diagonally dominant matrices play a wide and important role in computational mathematics, mathematical physics, theory of dynamical systems, etc. But it is difficult to judge a matrix is or not generalized strictly diagonally dominant matrix. In this paper, by using the properties of α-chain diagonally dominant matrix, we obtain new criteria for judging generalized strictly diagonally dominant matrix, which enlarge the identification range.

  14. Variantes anatómicas del septum pellucidum

    Directory of Open Access Journals (Sweden)

    P. Sartori

    2015-04-01

    Durante la vida embrionaria existen variantes anatómicas del septum pellucidum que se disponen en sentido rostro-dorsal. Estas son el cavum del septum pellucidum, el cavum vergae y el cavum velum interpositum. Su presencia o ausencia puede estar relacionada con alteraciones del desarrollo del sistema nervioso y trastornos cognitivo-psiquiátricos, por lo que deben conocerse bien para evitar diagnósticos erróneos.

  15. THE EXTRACTION LAMBERTSON SEPTUM MAGNET OF THE SNS.

    Energy Technology Data Exchange (ETDEWEB)

    RANK J.; MIGLIONICO, G.; RAPARIA, D.; TSOUPAS, N.; TUOZZOLO, J.; LEE, Y.Y.

    2005-05-16

    In the Spallation Neutron Source, after multiple injections to an accumulator ring, a final extraction delivers the full proton beam to the target, achieved by a series of kickers and a thin septum magnet. Here we discuss the lattice geometry, beam dynamics and optics, and the vacuum, electromagnetic and mechanical design aspects of the Extraction Lambertson Septum Magnet (ELS). Relevant data are established. Vector calculus is solved for pitch and roll angles, which are shown schematically in magnet sections.

  16. Methods of septum surgery (septoplasty) with cresto- and suturotomy

    OpenAIRE

    Gulimbay Babakhanov; Saidakram Khasanov; Sunnat Makhsudov; Maqsad Bobokhonov; Anvar Almamatov

    2012-01-01

    High frequency of a combination of such symptoms as a curvature of a nose septum (NSC) dento-maxillary anomalies (DMA), high standing of the palatum, reduction of the horizontal and vertical sizes of a cavity of a nose are united and named as Khasanov rhinomaxillary (orthodontic rhinological) symptom complex. The operative intervention - septum surgery with crestosuturotomy is prescribed to patients with Khasanov symptom complex. The musculomucosal graft is detached, a cartilage is separated ...

  17. Intraosseous hemangioma of the nasal septum: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Ho; Kim, Eui Jong; Jang, Ji Hye; Lee, Kyung Mi; Choi, Woo Suk; Kim, Sung Wan; Kim, Yoon Hwa [Kyung Hee University Hospital, Seoul (Korea, Republic of)

    2015-08-15

    Hemangioma can arise in the soft tissues and bone of the nasal cavity. However, to the best of our knowledge, there are no prior case reports presenting intraosseous hemangioma of the nasal septum. Intraosseous hemangioma, in addition to a chondroid tumor, should be included in the differential diagnosis of a calcified mass of the nasal cavity. In the present report, we present a case of an intraosseous cavernous hemangioma in the nasal bony septum of a 53-year-old woman.

  18. Compressive and tensile mechanical properties of the porcine nasal septum.

    Science.gov (United States)

    Al Dayeh, Ayman A; Herring, Susan W

    2014-01-03

    The expanding nasal septal cartilage is believed to create a force that powers midfacial growth. In addition, the nasal septum is postulated to act as a mechanical strut that prevents the structural collapse of the face under masticatory loads. Both roles imply that the septum is subject to complex biomechanical loads during growth and mastication. The purpose of this study was to measure the mechanical properties of the nasal septum to determine (1) whether the cartilage is mechanically capable of playing an active role in midfacial growth and in maintaining facial structural integrity and (2) if regional variation in mechanical properties is present that could support any of the postulated loading regimens. Porcine septal samples were loaded along the horizontal or vertical axes in compression and tension, using different loading rates that approximate the in vivo situation. Samples were loaded in random order to predefined strain points (2-10%) and strain was held for 30 or 120 seconds while relaxation stress was measured. Subsequently, samples were loaded until failure. Stiffness, relaxation stress and ultimate stress and strain were recorded. Results showed that the septum was stiffer, stronger and displayed a greater drop in relaxation stress in compression compared to tension. Under compression, the septum displayed non-linear behavior with greater stiffness and stress relaxation under faster loading rates and higher strain levels. Under tension, stiffness was not affected by strain level. Although regional variation was present, it did not strongly support any of the suggested loading patterns. Overall, results suggest that the septum might be mechanically capable of playing an active role in midfacial growth as evidenced by increased compressive residual stress with decreased loading rates. However, the low stiffness of the septum compared to surrounding bone does not support a strut role. The relatively low stiffness combined with high stress relaxation

  19. A Rare Case of Lipomatous Hypertrophy of the Interventricular Septum

    OpenAIRE

    Papadopoulos, Christodoulos E.; Matsiras, Sotirios; Vassilikos, Vassilios

    2016-01-01

    Asymmetrical left ventricular hypertrophy secondary to interventricular septum hypertrophy is usually considered a typical phenotype of hypertrophic cardiomyopathy. In rare cases other conditions such as tumors or lipomatous hypertrophy of the interventricular septum may have a similar presentation. We present a case of a male patient who presented for routine cardiology work up and was diagnosed of having ventricular septal hypertrophy secondary to localized lipomatous hypertrophy.

  20. Interaction of the tracheal tubules of Scutigera coleoptrata (Chilopoda, Notostigmophora with glandular structures of the pericardial septum

    Directory of Open Access Journals (Sweden)

    Gero Hilken

    2015-06-01

    Full Text Available Notostigmophora (Scutigeromorpha exhibit a special tracheal system compared to other Chilopoda. The unpaired spiracles are localized medially on the long tergites and open into a wide atrium from which hundreds of tracheal tubules originate and extend into the pericardial sinus. Previous investigators reported that the tracheal tubules float freely in the hemolymph. However, here we show for the first time that the tracheal tubules are anchored to a part of the pericardial septum. Another novel finding is this part of the pericardial septum is structured as an aggregated gland on the basis of its specialized epithelium being formed by hundreds of oligocellular glands. It remains unclear whether the pericardial septum has a differently structure in areas that lack a connection with tracheal tubules. The tracheal tubules come into direct contact with the canal cells of the glands that presumably secrete mucous substances covering the entire luminal cuticle of the tracheal tubules. Connections between tracheae and glands have not been observed in any other arthropods.

  1. Introduction to Hubbard model and exact diagonalization

    Directory of Open Access Journals (Sweden)

    S. Akbar Jafari

    2008-06-01

    Full Text Available  Hubbard model is an important model in the theory of strongly correlated electron systems. In this contribution we introduce this model and the concepts of electron correlation by building on a tight binding model. After enumerating various methods of tackling the Hubbard model, we introduce the numerical method of exact diagonalization in detail. The book keeping and practical implementation aspects are illustrated with analytically solvable example of two-site Hubbard model.

  2. Diagonalizing sensing matrix of broadband RSE

    Science.gov (United States)

    Sato, Shuichi; Kokeyama, Keiko; Kawazoe, Fumiko; Somiya, Kentaro; Kawamura, Seiji

    2006-03-01

    For a broadband-operated RSE interferometer, a simple and smart length sensing and control scheme was newly proposed. The sensing matrix could be diagonal, owing to a simple allocation of two RF modulations and to a macroscopic displacement of cavity mirrors, which cause a detuning of the RF modulation sidebands. In this article, the idea of the sensing scheme and an optimization of the relevant parameters will be described.

  3. Nail-patella-syndrome in a young patient followed up over 10 years: relevance of the sagittal trochlear septum for patellofemoral pathology

    Directory of Open Access Journals (Sweden)

    Konrads Christian

    2016-01-01

    Full Text Available Introduction: Nail-patella-syndrome (NPS is a rare autosomal-dominant inherited disease with pathologies of nails, skeleton, kidneys, and eyes. Linkage to a mutated gene was found. It codes for the transcription-factor LMX1B. In most cases knees are symptomatic. Patients have hypoplastic patellae, which are laterally subluxated. In those individuals a sagittal trochlear fibrous septum was found, dividing the anterior knee-joint-space. In the literature the etiology and clinical significance of this anatomic abnormality is unclear. Based on clinical and intraoperative findings we developed a theory regarding knee pathology in nail-patella-syndrome. Successful treatment via early resection of the septum with sustained good outcome is presented. Methods: In a symptomatic six-year-old boy with nail-patella-syndrome we resected the fibrous sagittal septum adherent to the trochlea femoris and we balanced the patella via lateral release and medial plication in both knee joints. We analyzed the clinical outcome of this procedure prospectively over 10 years. Results: Postoperatively the hypoplastic patellae stayed centered and stable during further skeletal development. The patient was still pain free with normal range of motion of both operated knee joints after 10 years of follow-up. Discussion: In patients with nail-patella-syndrome and a subluxated or dislocated patella we recommend diagnostics with magnetic-resonance-imaging and early surgical treatment via resection of the trochlear septum and soft-tissue-balancing of the patella. When the septum displaces the patella and prevents physiological articulation of the patella with the trochlea femoris, early septum resection is likely to be important for a good functional outcome and proper development of the patellofemoral joint during growth.

  4. Diagonal gates in the Clifford hierarchy

    Science.gov (United States)

    Cui, Shawn X.; Gottesman, Daniel; Krishna, Anirudh

    2017-01-01

    The Clifford hierarchy is a set of gates that appears in the theory of fault-tolerant quantum computation, but its precise structure remains elusive. We give a complete characterization of the diagonal gates in the Clifford hierarchy for prime-dimensional qudits. They turn out to be pmth roots of unity raised to polynomial functions of the basis state to which they are applied, and we determine which level of the Clifford hierarchy a given gate sits in based on m and the degree of the polynomial.

  5. Exact diagonalization of quantum-spin models

    Science.gov (United States)

    Lin, H. Q.

    1990-10-01

    We have developed a technique to replace hashing in implementing the Lanczös method for exact diagonalization of quantum-spin models that enables us to carry out numerical studies on substantially larger lattices than previously studied. We describe the algorithm in detail and present results for the ground-state energy, the first-excited-state energy, and the spin-spin correlations on various finite lattices for spins S=1/2, 1, 3/2, and 2. Results for an infinite system are obtained by extrapolation. We also discuss the generalization of our method to other models.

  6. Diagonally non-computable functions and fireworks

    OpenAIRE

    Bienvenu, Laurent; Patey, Ludovic

    2014-01-01

    A set C of reals is said to be negligible if there is no probabilistic algorithm which generates a member of C with positive probability. Various classes have been proven to be negligible, for example the Turing upper-cone of a non-computable real, the class of coherent completions of Peano Arithmetic or the class of reals of minimal degrees. One class of particular interest in the study of negligibility is the class of diagonally non-computable (DNC) functions, proven by Kucera to be non-neg...

  7. Arthroscopic partial medial meniscectomy

    Directory of Open Access Journals (Sweden)

    Dašić Žarko

    2011-01-01

    Full Text Available Background/Aim. Meniscal injuries are common in professional or recreational sports as well as in daily activities. If meniscal lesions lead to physical impairment they usually require surgical treatment. Arthroscopic treatment of meniscal injuries is one of the most often performed orthopedic operative procedures. Methods. The study analyzed the results of arthroscopic partial medial meniscectomy in 213 patients in a 24-month period, from 2006, to 2008. Results. In our series of arthroscopically treated medial meniscus tears we noted 78 (36.62% vertical complete bucket handle lesions, 19 (8.92% vertical incomplete lesions, 18 (8.45% longitudinal tears, 35 (16.43% oblique tears, 18 (8.45% complex degenerative lesions, 17 (7.98% radial lesions and 28 (13.14% horisontal lesions. Mean preoperative International Knee Documentation Committee (IKDC score was 49.81%, 1 month after the arthroscopic partial medial meniscectomy the mean IKDC score was 84.08%, and 6 months after mean IKDC score was 90.36%. Six months after the procedure 197 (92.49% of patients had good or excellent subjective postoperative clinical outcomes, while 14 (6.57% patients subjectively did not notice a significant improvement after the intervention, and 2 (0.93% patients had no subjective improvement after the partial medial meniscectomy at all. Conclusion. Arthroscopic partial medial meniscetomy is minimally invasive diagnostic and therapeutic procedure and in well selected cases is a method of choice for treatment of medial meniscus injuries when repair techniques are not a viable option. It has small rate of complications, low morbidity and fast rehabilitation.

  8. Upflow bioreactor with septum and pressure release mechanism

    Science.gov (United States)

    Hansen, Conly L.; Hansen, Carl S.; Pack, Kevin; Milligan, John; Benefiel, Bradley C.; Tolman, C. Wayne; Tolman, Kenneth W.

    2010-04-20

    An upflow bioreactor includes a vessel having an inlet and an outlet configured for upflow operation. A septum is positioned within the vessel and defines a lower chamber and an upper chamber. The septum includes an aperture that provides fluid communication between the upper chamber and lower chamber. The bioreactor also includes means for releasing pressure buildup in the lower chamber. In one configuration, the septum includes a releasable portion having an open position and a closed position. The releasable portion is configured to move to the open position in response to pressure buildup in the lower chamber. In the open position fluid communication between the lower chamber and the upper chamber is increased. Alternatively the lower chamber can include a pressure release line that is selectively actuated by pressure buildup. The pressure release mechanism can prevent the bioreactor from plugging and/or prevent catastrophic damage to the bioreactor caused by high pressures.

  9. [A case of neurinoma of the nasal septum].

    Science.gov (United States)

    Sakamoto, Kikuo; Gondo, Kyujiro; Tomita, Kazuhide; Kasuya, Takao

    2003-05-01

    Neurinoma grows in the modulated nerve with Schwann cells, and is observed for all positions of the body. It is comparatively rare for neurinoma to grow in the nasal cavity and paranasal sinuses, however. We report a case of neurinoma of the nasal septum. A 24-year-old man seen for nasal obstruction was found in anterior rhinoscopy to have a tumor of the bilateral nasal cavity. Computed tomography (CT) showed a soft tissue density mass in the anterior part of the nasal cavity. Because we suspected neurinoma from biopsy, we resected the tumor by Denker's operation under general anesthesia. We found that it originated from the nasal septum. Histopathological findings of the tumor indicated an Antoni A type neurinoma. After surgery, cartilago costalis was transplanted the plastic surgery to correct the defect in the nasal septum. The post operative course was good and no signs of recurrence were seen. This is the 19th case found in the literature.

  10. A 77-118 GHz Resonance-free Septum Polarizer

    CERN Document Server

    Chen, Yen-Lin; Teng, Hsiao-Feng

    2014-01-01

    Measurements of the polarized radiation often reveal specific physical properties of emission sources, such as strengths and orientations of magnetic fields offered by synchrotron radiation and Zeeman line emission, and the electron density distribution by free-free emission. Polarization-capable, millimeter/sub-millimeter telescopes are normally equipped with either septum polarizers or ortho-mode transducers (OMT) for the detection of polarized radiation. While the septum polarizer is traditionally conceived to be limited to a significantly narrower bandwidth than the OMT, it does possess advantageous features for astronomical polarization measurements unparalleled by the OMT. Challenging the conventional bandwidth limit, we design an extremely wideband circular waveguide septum polarizer, covering $42\\%$ bandwidth, from 77 GHz to 118 GHz, without any undesired resonance. Stokes parameters constructed from the measured data in between 77 GHz and 115 GHz show that the leakage from $I$ to $Q$ and $U$ is below...

  11. Nasal septum perforation in patient with pyoderma gangrenosum

    Directory of Open Access Journals (Sweden)

    Maia, Camilla Bezerra da Cruz

    2012-01-01

    Full Text Available Introduction: The cocaine is obtained from the leaves of the coca (Erythroxylon coca. It can be used in many ways, but the most common is the drug inhalation. The Cocaine also causes vasoconstriction at nasal mucous membrane and its chronic use can cause necrosis and nasal septum perforation. Pyoderma gangrenosum is an uncommon idiopathic disease characterized by ulcerations, usually observed on the legs. Its diagnosis is most common an exclusion of others diseases. So far, there is no specific treatment based on evidence by randomized controlled trials. Objective: Describe the rare association between Pyoderma gangrenosum and cocaine. Case Report: E. A., 27-year-old woman with destruction of nasal septum and palate who has been using a big amount of cocaine, been necessary note the difference from which disease cause de damage. Final Comments: Also there are only three cases of Pyoderma gangrenosum complicated with nasal septum perforation in cocaine users.

  12. Persistent truncus arteriosus with intact ventricular septum diagnosed by echocardiography

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yu-qi; SHEN Rong; SUN Kun; ZHONG Shu-wen; WU Yu-rong

    2009-01-01

    Persistent truncus arteriosus (PTA) is a rare congenital cardiac anomaly, and has an incidence of about 0.5 to 0.9 per 10 000 live births. Almost all cases described in the literatures had a large ventricular septal defect, only few rare cases were reported with intact ventricular septum. From June 1998 to December 2008, cardiac angiography were performed in 10 880 patients with congenital heart disease in our hospital, 47 patients with PTA were diagnosed, one case with tricuspid atresia,hypoplastic right ventricle, and intact ventricular septum was encountered.

  13. Diagonal stripes in the spin glass phase of cuprates

    Energy Technology Data Exchange (ETDEWEB)

    Seibold, G., E-mail: goetz@physik.tu-cottbus.d [Institut fuer Physik, BTU Cottbus, Post Box 101344, 03013 Cottbus (Germany); Lorenzana, J. [SMC-INFM-CNR and Dipartimento di Fisica, Universita di Roma ' La Sapienza' , P.le Aldo Moro 5, I-00185 Roma (Italy)

    2010-12-15

    Based on the unrestricted Gutzwiller approximation we study the possibility that the diagonal incommensurate spin scattering in the spin glass phase of lanthanum cuprates originates from stripe formation. Similar to the metallic phase two types of diagonal stripe structures appear to be stable: (a) site-centered textures which have one hole per site along the stripe and (b) ferromagnetic stair-case structures which are the diagonal equivalent to bond-centered stripes in the metallic phase and which on average have a filling of 3/4 holes per stripe site. We give a detailed analysis of the stability of both diagonal textures with regard to the vertical ones.

  14. Septum necrosis following CPAP treatment of preterm infant

    DEFF Research Database (Denmark)

    Fjaeldstad, Alexander; Cipliene, Rasa; Ramsgaard-Jensen, Trine

    2014-01-01

    This case describes the complications of intensive respiratory support in a preterm infant. During two months of rigorous nasal continuous positive airway pressure (CPAP) therapy with intermittent use of CPAP-mask and -prongs, an ulcer in the nasal mucus membrane developed into septum necrosis...

  15. [Use of Solcoseryl DAP after nasal septum surgery].

    Science.gov (United States)

    Krzeski, A; Makowska, W

    1991-01-01

    Solcoseryl is a biological agent, which accelerates the healing tissue procedure. This influence was studied during the nasal septum surgery. In 25 patients the postoperational nasal plug was inserted with the Solcoseryl and in 10 (control) with the paraffin. The cytologic verifications were performed before and after the surgery. In the solcoseryl group the mucosa regeneration procedure was accelerated and the inflammation reduced.

  16. A 77-118 GHz RESONANCE-FREE SEPTUM POLARIZER

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yen-Lin; Chiueh, Tzihong; Teng, Hsiao-Feng, E-mail: chiuehth@phys.ntu.edu.tw [Department of Physics, National Taiwan University, 106 Taipei, Taiwan (China)

    2014-03-01

    Measurements of polarized radiation often reveal specific physical properties of emission sources, such as the strengths and orientations of magnetic fields offered by synchrotron radiation and Zeeman line emission, and the electron density distribution caused by free-free emission. Polarization-capable, millimeter/sub-millimeter telescopes are normally equipped with either septum polarizers or ortho-mode transducers (OMT) to detect polarized radiation. Though the septum polarizer is limited to a significantly narrower bandwidth than the OMT, it possesses advantageous features unparalleled by the OMT when it comes to determining astronomical polarization measurements. We design an extremely wide-band circular waveguide septum polarizer, covering 42% bandwidth, from 77 GHz to 118 GHz, without any undesired resonance, challenging the conventional bandwidth limit. Stokes parameters, constructed from the measured data between 77 GHz and 115 GHz, show that the leakage from I to Q and U is below ±2%, and the Q – U mutual leakage is below ±1%. Such a performance is comparable to other modern polarizers, but the bandwidth of this polarizer can be at least twice as wide. This extremely wide-band design removes the major weakness of the septum polarizer and opens up a new window for future astronomical polarization measurements.

  17. A 77-118 GHz Resonance-free Septum Polarizer

    Science.gov (United States)

    Chen, Yen-Lin; Chiueh, Tzihong; Teng, Hsiao-Feng

    2014-03-01

    Measurements of polarized radiation often reveal specific physical properties of emission sources, such as the strengths and orientations of magnetic fields offered by synchrotron radiation and Zeeman line emission, and the electron density distribution caused by free-free emission. Polarization-capable, millimeter/sub-millimeter telescopes are normally equipped with either septum polarizers or ortho-mode transducers (OMT) to detect polarized radiation. Though the septum polarizer is limited to a significantly narrower bandwidth than the OMT, it possesses advantageous features unparalleled by the OMT when it comes to determining astronomical polarization measurements. We design an extremely wide-band circular waveguide septum polarizer, covering 42% bandwidth, from 77 GHz to 118 GHz, without any undesired resonance, challenging the conventional bandwidth limit. Stokes parameters, constructed from the measured data between 77 GHz and 115 GHz, show that the leakage from I to Q and U is below ±2%, and the Q - U mutual leakage is below ±1%. Such a performance is comparable to other modern polarizers, but the bandwidth of this polarizer can be at least twice as wide. This extremely wide-band design removes the major weakness of the septum polarizer and opens up a new window for future astronomical polarization measurements.

  18. Design and construction of septum magnets at the 7-GeV APS.

    Energy Technology Data Exchange (ETDEWEB)

    Gorski, A.

    1999-04-20

    The mechanical design, construction, and assembly procedure of six different septum magnet designs used in the Advanced Photon Source (APS) facility will be described. This will include a positron accumulator ring (PAR) AC septum magnet, a synchrotrons thin injection septum AC thin and thick extraction septa, and storage ring AC thick and thin injection septum magnets. Design parameters, material selection, assembly procedures, and operational results will be presented.

  19. Finite-Time Attractivity for Diagonally Dominant Systems with Off-Diagonal Delays

    Directory of Open Access Journals (Sweden)

    T. S. Doan

    2012-01-01

    Full Text Available We introduce a notion of attractivity for delay equations which are defined on bounded time intervals. Our main result shows that linear delay equations are finite-time attractive, provided that the delay is only in the coupling terms between different components, and the system is diagonally dominant. We apply this result to a nonlinear Lotka-Volterra system and show that the delay is harmless and does not destroy finite-time attractivity.

  20. Septum magnet for ejection from the PS to the E-Hall

    CERN Multimedia

    1977-01-01

    Pulsed septum magnet for ejection from PS straight sections 61/62 to the East-Hall. This septum magnet, for ss 61, had only 1 turn, for minimum thickness. It was followed by another septum in ss 62, with 2 turns, as there the ejected beam was already farther away from the circulating beam. Both septa were water-cooled.

  1. Quantum Monte Carlo diagonalization method as a variational calculation

    Energy Technology Data Exchange (ETDEWEB)

    Mizusaki, Takahiro; Otsuka, Takaharu [Tokyo Univ. (Japan). Dept. of Physics; Honma, Michio

    1997-05-01

    A stochastic method for performing large-scale shell model calculations is presented, which utilizes the auxiliary field Monte Carlo technique and diagonalization method. This method overcomes the limitation of the conventional shell model diagonalization and can extremely widen the feasibility of shell model calculations with realistic interactions for spectroscopic study of nuclear structure. (author)

  2. Generalized coordinate Bethe ansatz for non diagonal boundaries

    CERN Document Server

    Crampe, N

    2011-01-01

    We compute the spectrum and the eigenstates of the open XXX model with non-diagonal (triangular) boundary matrices. Since the boundary matrices are not diagonal, the usual coordinate Bethe ansatz does not work anymore, and we use a generalization of it to solve the problem.

  3. Optimization of fuzzy logic analysis by diagonals for pattern recognition

    Science.gov (United States)

    Habiballa, Hashim; Hires, Matej

    2017-07-01

    The article presents an optimization of the fuzzy logic analysis method for pattern recognition. The enhancements of the original method through the usage of additional two types of pattern components - leftwise diagonal and rightwise diagonal ones. The method is described in theoretical background and further articles show the implementation and experimental verification of the approach.

  4. Medial canthus retiform hemangioendothelioma

    Directory of Open Access Journals (Sweden)

    Yasser H Al-Faky

    2014-01-01

    Full Text Available Retiform hemangioendothelioma (RH is a distinct entity in the spectrum of vascular tumors with a high local recurrence rate. It is considered a low-grade, well-differentiated cutaneous angiosarcoma with low metastatic potential. We report here for the first time a case of medial canthus recurrent RH. It may be helpful in our practice to include RH as a differential diagnosis of eyelid lesions. It is noteworthy that the progressive course and recurrence tendency of RH might be misdiagnosed as angiosarcoma or basal cell carcinoma (BCC, if not expected and carefully evaluated by the pathologist.

  5. Crisscross heart with dextrocardia and intact interventricular septum

    Directory of Open Access Journals (Sweden)

    P Kader Muneer

    2014-01-01

    Full Text Available Crisscross heart is a rare congenital heart disease characterized by a twisted atrioventricular connection, as a result of rotation of the ventricular mass along its long axis. We report an asymptomatic 48-year-old woman referred to us for evaluation of a cardiac murmur. Further evaluation showed situs solitus, dextrocardia with normal atrioventricular and ventriculoarterial connection, and a crisscross relation of the atrioventricular valves. Unlike the usual case of crisscross heart, our patient had an intact ventricular septum.

  6. Ectopic Supernumerary Tooth in Nasal Septum: A Case Study

    Directory of Open Access Journals (Sweden)

    Saleh Mohebbi

    2013-06-01

    Full Text Available Introduction: Nasal teeth eruption is a rare phenomenon. The variability of symptoms and generic history makes the diagnosis difficult. This difficulty is more challenging when the tooth is placed in the depth of septum.   Case Report: Our case is an example of this problem. Herein, we present a case of intraseptal tooth with nasal obstruction and septal deviation and recurrent sinusitis. We present preoperative imaging.   Conclusion: Great suspicion may helpful for preoperative diagnosis and good deciding.

  7. Ectopic Supernumerary Tooth in Nasal Septum: A Case Study

    Directory of Open Access Journals (Sweden)

    Saleh Mohebbi

    2013-06-01

    Full Text Available Introduction: Nasal teeth eruption is a rare phenomenon. The variability of symptoms and generic history makes the diagnosis difficult. This difficulty is more challenging when the tooth is placed in the depth of septum.   Case Report: Our case is an example of this problem. Herein, we present a case of intraseptal tooth with nasal obstruction and septal deviation and recurrent sinusitis. We present preoperative imaging.   Conclusion: Great suspicion may helpful for preoperative diagnosis and good deciding.

  8. Teleportation of an arbitrary mixture of diagonal states of multiqudit

    Institute of Scientific and Technical Information of China (English)

    Du Qian-Hua; Lin Xiu-Min; Chen Zhi-Hua; Lin Gong-Wei; Chen Li-Bo; Gu Yong-Jian

    2008-01-01

    This paper proposes a scheme to teleport an arbitrary mixture of diagonal states of multiqutrit via classical correlation and classical communication. To teleport an arbitrary mixture of diagonal states of N qutrits, N classically correlated pairs of two qutrits are used as channel. The sender (Alice) makes Fourier transform and conditional gate (i.e., XOR(3) gate) on her qutrits and does measurement in appropriate computation bases. Then she sends N ctrits to the receiver (Bob). Based on the received information, Bob performs the corresponding unitary transformation on his qutrits and obtains the teleported state. Teleportation of an arbitrary mixture of diagonal states of multiqudit is also discussed.

  9. NONLINEAR BENDING THEORY OF DIAGONAL SQUARE PYRAMID RETICULATED SHALLOW SHELLS

    Institute of Scientific and Technical Information of China (English)

    肖潭; 刘人怀

    2001-01-01

    Double-deck reticulated shells are a main form of large space structures. One of the shells is the diagonal square pyramid reticulated shallow shell, whose its upper and lower faces bear most of the load but its core is comparatively flexible. According to its geometrical and mechanical characteristics, the diagonal square pyramid reticulated shallow shell is treated as a shallow sandwich shell on the basis of three basic assumptions. Its constitutive relations are analyzed from the point of view of energy and internal force equivalence. Basic equations of the geometrically nonlinear bending theory of the diagonal square pyramid reticulated shallow shell are established by means of the virtual work principle .

  10. Diagonal representation for a generic matrix valued quantum Hamiltonian

    Energy Technology Data Exchange (ETDEWEB)

    Gosselin, Pierre [Universite Grenoble I, Institut Fourier, UMR 5582 CNRS-UJF UFR de Mathematiques, BP74, Saint Martin d' Heres Cedex (France); Mohrbach, Herve [Universite Paul Verlaine-Metz, Laboratoire de Physique Moleculaire et des Collisions, ICPMB-FR CNRS 2843, Metz Cedex 3 (France)

    2009-12-15

    A general method to derive the diagonal representation for a generic matrix valued quantum Hamiltonian is proposed. In this approach new mathematical objects like non-commuting operators evolving with the Planck constant promoted as a running variable are introduced. This method leads to a formal compact expression for the diagonal Hamiltonian which can be expanded in a power series of the Planck constant. In particular, we provide an explicit expression for the diagonal representation of a generic Hamiltonian to the second order in the Planck constant. This result is applied, as a physical illustration, to Dirac electrons and neutrinos in external fields. (orig.)

  11. Using off-diagonal confinement as a cooling method

    Science.gov (United States)

    Rousseau, Valery; Hettiarachchilage, Kalani; Moreno, Juana; Jarrell, Mark; Sheehy, Dan

    2011-03-01

    We show that the recently proposed ``off-diagonal confining" (ODC) method (Phys. Rev. Lett. 104, 167201 (2010)) can lead to temperatures that are smaller than with the conventional ``diagonal confining" (DC) method, depending on the control parameters of the system. We determine these parameters using exact diagonalizations for the hard-core case, then we extend our results to the soft-core case by performing quantum Monte Carlo simulations for both DC and ODC systems at fixed temperatures, and analysing the corresponding entropies. This work was supported by NSF OISE-0952300.

  12. Cavum Septum Pellucidum in Retired American Pro-Football Players.

    Science.gov (United States)

    Gardner, Raquel C; Hess, Christopher P; Brus-Ramer, Marcel; Possin, Katherine L; Cohn-Sheehy, Brendan I; Kramer, Joel H; Berger, Mitchel S; Yaffe, Kristine; Miller, Bruce; Rabinovici, Gil D

    2016-01-01

    Previous studies report that cavum septum pellucidum (CSP) is frequent among athletes with a history of repeated traumatic brain injury (TBI), such as boxers. Few studies of CSP in athletes, however, have assessed detailed features of the septum pellucidum in a case-control fashion. This is important because prevalence of CSP in the general population varies widely (2% to 85%) between studies. Further, rates of CSP among American pro-football players have not been described previously. We sought to characterize MRI features of the septum pellucidum in a series of retired pro-football players with a history of repeated concussive/subconcussive head traumas compared with controls. We retrospectively assessed retired American pro-football players presenting to our memory clinic with cognitive/behavioral symptoms in whom structural MRI was available with slice thickness ≤2 mm (n=17). Each player was matched to a memory clinic control patient with no history of TBI. Scans were interpreted by raters blinded to clinical information and TBI/football history, who measured CSP grade (0-absent, 1-equivocal, 2-mild, 3-moderate, 4-severe) and length according to a standard protocol. Sixteen of 17 (94%) players had a CSP graded ≥2 compared with 3 of 17 (18%) controls. CSP was significantly higher grade (pfootball players compared with patients without a history of TBI.

  13. Methods of septum surgery (septoplasty with cresto- and suturotomy

    Directory of Open Access Journals (Sweden)

    Gulimbay Babakhanov

    2012-12-01

    Full Text Available High frequency of a combination of such symptoms as a curvature of a nose septum (NSC dento-maxillary anomalies (DMA, high standing of the palatum, reduction of the horizontal and vertical sizes of a cavity of a nose are united and named as Khasanov rhinomaxillary (orthodontic rhinological symptom complex. The operative intervention - septum surgery with crestosuturotomy is prescribed to patients with Khasanov symptom complex. The musculomucosal graft is detached, a cartilage is separated from the bottom of a nasal cavity and moved in the opposite side. Thus the nasal crest of a palatal shoot of the top jaw becomes visible and it is removed with a grooved chisel (crestotomy. Suturotomy is made to sutura palatina mediana of the bony palate which is from 2- to 5-mm deep and up to 3-4-mm wide in the form of a trihedral trench. Our experience shows that, patients with Khasanov symptom complex after surgical correction of the nasal septum and osteotomy of the nasal crest of a palatal shoot of the top jaw, the orthodontic disclosing of a palatal stitch occurs several times faster, anomaly relapses of dento-maxillary systems decrease.

  14. EXTREME POINTS IN DIAGONAL-DISJOINT IDEALS OF NEST ALGEBRAS

    Institute of Scientific and Technical Information of China (English)

    董浙; 鲁世杰

    2002-01-01

    In this paper, the extreme points of the unit ball of diagonal-disjoint ideals in nest algebras are characterized completely; Furthermore, it is shown that every extreme point of the unit ball of 2 has essential-norm one.

  15. Multivariate Diagonal Coinvariant Spaces for Complex Reflection Groups

    CERN Document Server

    Bergeron, Francois

    2011-01-01

    For finite complex reflexion groups, we consider the graded $W$-modules of diagonally harmonic polynomials in $r$ sets of variables, and show that associated Hilbert series may be described in a global manner, independent of the value of $r$.

  16. Multivariable Decoupling Control System Based on Generalized Diagonal Dominance

    Directory of Open Access Journals (Sweden)

    S. Jamebozorg

    2015-03-01

    Full Text Available In this paper, the design of static precompensator for the reduction of interaction in linear multivariable systems is proposed. In the previous studies, the diagonal dominance of systems in special frequency range has been less paid attention to. In the proposed method, some static compensators with matrix coefficients are combined so that the final static compensator can make system diagonal dominance in a wide range of frequencies. These coefficients are obtained with optimization algorithm. In this method, to achieve diagonal dominance with less conservativeness, the criterion of generalized diagonal dominance is used. The proposed method does not have any limitation for systems with high interaction or non-minimum phase systems. In comparison with some common methods, it has a simpler structure with easy implementation. Simulation examples demonstrate the usefulness of the proposed method

  17. Online blind source separation based on joint diagonalization

    Institute of Scientific and Technical Information of China (English)

    Li Ronghua; Zhou Guoxu; Fang Zuyuan; Xie Shengli

    2009-01-01

    A now algorithm is proposed for joint diagonalization. With a modified objective function, the now algorithm not only excludes trivial and unbalanced solutions successfully, but is also easily optimized. In addition, with the new objective function, the proposed algorithm can work well in online blind source separation (BSS) for the first time, although this family of algorithms is always thought to be valid only in batch-mode BSS by far. Simulations show that it is a very competitive joint diagonalization algorithm.

  18. Self-excitation of a diagonal MHD channel

    Energy Technology Data Exchange (ETDEWEB)

    Doperchuk, I.I.; Koneyev, S.M.A.

    1982-01-01

    Questions are examined of self-excitation of a diagonal MHD channel. Conditions are obtained for self-excitation using 0-dimensional approximation. An algorithm is presented for calculating the optimal self-exciting diagonal channel with regard for development and separation of the boundary layers, presence of near-electrode drops in voltage. Graphs are presented for the transitional regimes of channel operation with intermediate point of connection of the excitation winding.

  19. Discriminative Block-Diagonal Representation Learning for Image Recognition.

    Science.gov (United States)

    Zhang, Zheng; Xu, Yong; Shao, Ling; Yang, Jian

    2017-07-04

    Existing block-diagonal representation studies mainly focuses on casting block-diagonal regularization on training data, while only little attention is dedicated to concurrently learning both block-diagonal representations of training and test data. In this paper, we propose a discriminative block-diagonal low-rank representation (BDLRR) method for recognition. In particular, the elaborate BDLRR is formulated as a joint optimization problem of shrinking the unfavorable representation from off-block-diagonal elements and strengthening the compact block-diagonal representation under the semisupervised framework of LRR. To this end, we first impose penalty constraints on the negative representation to eliminate the correlation between different classes such that the incoherence criterion of the extra-class representation is boosted. Moreover, a constructed subspace model is developed to enhance the self-expressive power of training samples and further build the representation bridge between the training and test samples, such that the coherence of the learned intraclass representation is consistently heightened. Finally, the resulting optimization problem is solved elegantly by employing an alternative optimization strategy, and a simple recognition algorithm on the learned representation is utilized for final prediction. Extensive experimental results demonstrate that the proposed method achieves superb recognition results on four face image data sets, three character data sets, and the 15 scene multicategories data set. It not only shows superior potential on image recognition but also outperforms the state-of-the-art methods.

  20. Diagonal and off-diagonal susceptibilities of conserved quantities in relativistic heavy-ion collisions

    CERN Document Server

    Chatterjee, Arghya; Nayak, Tapan K; Sahoo, Nihar Ranjan

    2016-01-01

    Susceptibilities of conserved quantities, such as baryon number, strangeness and electric charge are sensitive to the onset of quantum chromodynamics (QCD) phase transition and are expected to provide information on the matter produced in heavy-ion collision experiments. A comprehensive study of the second-order diagonal susceptibilities and cross correlations has been made within a thermal model approach of the hadron resonance gas (HRG) model as well as with a hadronic transport model, UrQMD. We perform a detailed analysis of the effect of detector acceptances and choice of particle species in the experimental measurements of the susceptibilities for heavy-ion collisions corresponding to \\sNN = 4 GeV to 200 GeV. The transverse momentum cutoff dependence of suitably normalised susceptibilities are proposed as useful observables to probe the properties of the medium at freezeout.

  1. Diagonal and off-diagonal susceptibilities of conserved quantities in relativistic heavy-ion collisions

    Science.gov (United States)

    Chatterjee, Arghya; Chatterjee, Sandeep; Nayak, Tapan K.; Ranjan Sahoo, Nihar

    2016-12-01

    Susceptibilities of conserved quantities, such as baryon number, strangeness and electric charge are sensitive to the onset of quantum chromodynamics phase transition, and are expected to provide information on the matter produced in heavy-ion collision experiments. A comprehensive study of the second order diagonal susceptibilities and cross correlations has been made within a thermal model approach of the hadron resonance gas model as well as with a hadronic transport model, ultra-relativistic quantum molecular dynamics. We perform a detailed analysis of the effect of detector acceptances and choice of particle species in the experimental measurements of the susceptibilities for heavy-ion collisions corresponding to \\sqrt{{s}{NN}} = 4 GeV to 200 GeV. The transverse momentum cutoff dependence of suitably normalised susceptibilities are proposed as useful observables to probe the properties of the medium at freezeout.

  2. [Primary amenorrhea by transverse vaginal septum: a case report and review of the literature].

    Science.gov (United States)

    González-Zárate, Alba Citlalli; Velásquez-Mamani, Jaime

    2014-09-01

    The transverse vaginal septum is one of the rarest anomalies of the reproductive tract classified depending on location. It is manifested by primary amenorrhea, cyclic pain and progressive mass growth at abdominopelvic level, ultrasound and magnetic resonance imaging provides the diagnosis, location and thickness of a transverse vaginal septum, treatment is surgical. We present a case of a teenage patient with primary amenorrhea due to lower transverse vaginal septum with surgical resection and satisfactory follow-up with successful vaginal patency.

  3. Auditory spatial resolution in horizontal, vertical, and diagonal planes.

    Science.gov (United States)

    Grantham, D Wesley; Hornsby, Benjamin W Y; Erpenbeck, Eric A

    2003-08-01

    Minimum audible angle (MAA) and minimum audible movement angle (MAMA) thresholds were measured for stimuli in horizontal, vertical, and diagonal (60 degrees) planes. A pseudovirtual technique was employed in which signals were recorded through KEMAR's ears and played back to subjects through insert earphones. Thresholds were obtained for wideband, high-pass, and low-pass noises. Only 6 of 20 subjects obtained wideband vertical-plane MAAs less than 10 degrees, and only these 6 subjects were retained for the complete study. For all three filter conditions thresholds were lowest in the horizontal plane, slightly (but significantly) higher in the diagonal plane, and highest for the vertical plane. These results were similar in magnitude and pattern to those reported by Perrott and Saberi [J. Acoust. Soc. Am. 87, 1728-1731 (1990)] and Saberi and Perrott [J. Acoust. Soc. Am. 88, 2639-2644 (1990)], except that these investigators generally found that thresholds for diagonal planes were as good as those for the horizontal plane. The present results are consistent with the hypothesis that diagonal-plane performance is based on independent contributions from a horizontal-plane system (sensitive to interaural differences) and a vertical-plane system (sensitive to pinna-based spectral changes). Measurements of the stimuli recorded through KEMAR indicated that sources presented from diagonal planes can produce larger interaural level differences (ILDs) in certain frequency regions than would be expected based on the horizontal projection of the trajectory. Such frequency-specific ILD cues may underlie the very good performance reported in previous studies for diagonal spatial resolution. Subjects in the present study could apparently not take advantage of these cues in the diagonal-plane condition, possibly because they did not externalize the images to their appropriate positions in space or possibly because of the absence of a patterned visual field.

  4. Electrostatic septum for "Continuous Transfer" from PS to SPS

    CERN Multimedia

    1982-01-01

    For "Continuous Transfer" to the SPS, the PS beam, after acceleration, is peeled off in 5 turns. To minimize losses, the magnetic septa are preceded by an electrostatic septum in straight section 31. We see the inner part of it, on a lab-bench. The first part consists of W-wires, the second part is a Mo-foil. The circulating beam passes through the opening, the ejected beam at the outside (above the wires, in this picture). This assembly is the anode-part, the cathode is not shown.

  5. Partial tearing of the interventricular septum after blunt chest trauma.

    Science.gov (United States)

    López-Ruiz, Nilson; Ramírez Gil, Lucas

    2015-01-01

    Cardiac trauma after blunt chest trauma is a rare complication of patients arriving alive to an emergency department. We here present the case of patient who had a partial rupture of the interventricular septum after having had a blunt chest trauma in a traffic accident. As there was no ventricular septal defect, conservative management was deemed appropriate. At 3-year follow-up, the patient was free of right heart failure symptoms suggestive of the septal defect progression. Copyright © 2015 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

  6. Papillary muscle approximation to septum for functional tricuspid regurgitation.

    Science.gov (United States)

    Lohchab, Shamsher Singh; Chahal, Ashok Kumar; Agrawal, Nilesh

    2015-07-01

    Current techniques for repair of functional tricuspid regurgitation are associated with a significant degree of residual or recurrent regurgitation. We describe a technique of anterior papillary muscle attachment to the septum to correct residual tricuspid regurgitation persisting after annuloplasty. In our early experience in 15 patients (6 men and 9 women) with a mean age of 32 ± 11 years, who underwent annuloplasty for severe functional tricuspid regurgitation secondary to rheumatic mitral valve disease, this technique effectively eliminated residual tricuspid regurgitation.

  7. Chondrosarcoma of the paranasal sinuses and nasal septum.

    Science.gov (United States)

    El Ghazali, A M

    1983-06-01

    A case of chondrosarcoma of the left antro-ethmoid region and nasal septum is presented as a second primary malignant tumour in a patient who had undergone a previous excision of a rodent ulcer in the cheek. X-ray studies and multiple biopsies of the nasal cavity were undertaken to determine as accurately as possible the extent of the tumour. The tumour was excised via a lateral rhinotomy. Chondrosarcoma of the maxillofacial region is a rare tumour. The treatment of choice is by surgical excision. Radiotherapy may be considered in non-resectable or recurrent tumours.

  8. Correlations and diagonal entropy after quantum quenches in XXZ chains

    Science.gov (United States)

    Piroli, Lorenzo; Vernier, Eric; Calabrese, Pasquale; Rigol, Marcos

    2017-02-01

    We study quantum quenches in the XXZ spin-1 /2 Heisenberg chain from families of ferromagnetic and antiferromagnetic initial states. Using Bethe ansatz techniques, we compute short-range correlators in the complete generalized Gibbs ensemble (GGE), which takes into account all local and quasilocal conservation laws. We compare our results to exact diagonalization and numerical linked cluster expansion calculations for the diagonal ensemble, finding excellent agreement and thus providing a very accurate test for the validity of the complete GGE. Furthermore, we use exact diagonalization to compute the diagonal entropy in the postquench steady state. We show that the Yang-Yang entropy for the complete GGE is consistent with twice the value of the diagonal entropy in the largest chains or the extrapolated result in the thermodynamic limit. Finally, the complete GGE is quantitatively contrasted with the GGE built using only the local conserved charges (local GGE). The predictions of the two ensembles are found to differ significantly in the case of ferromagnetic initial states. Such initial states are better suited than others considered in the literature to experimentally test the validity of the complete GGE and contrast it to the failure of the local GGE.

  9. Net efficiency of roller skiing with a diagonal stride.

    Science.gov (United States)

    Nakai, Akira; Ito, Akira

    2011-02-01

    The aims of this study were: (a) to determine net efficiency during roller skiing with a diagonal stride at various speeds; (b) to assess the development of net efficiency across speeds; and (c) to examine the characteristics of efficiency in diagonal roller skiing. Two-dimensional kinematics and oxygen uptake were determined in eight male collegiate cross-country ski athletes who roller skied with the diagonal stride at various speeds on a level track. Net efficiency was calculated from rates of internal and external work and net energy expenditure. Individual net efficiency ranged from 17.7% to 52.1%. Net efficiency in the entire group of athletes increased with increasing speed, reached a maximum value of 37.3% at 3.68 m · s(-1), before slowly decreasing. These findings indicate that roller skiing with the diagonal stride at high speed is a highly efficient movement and that an optimal speed exists at which net efficiency can be maximally enhanced in diagonal roller skiing.

  10. Automated septum thickness measurement--a Kalman filter approach.

    Science.gov (United States)

    Snare, Sten Roar; Mjølstad, Ole Christian; Orderud, Fredrik; Dalen, Håvard; Torp, Hans

    2012-11-01

    Interventricular septum thickness in end-diastole (IVSd) is one of the key parameters in cardiology. This paper presents a fast algorithm, suitable for pocket-sized ultrasound devices, for measurement of IVSd using 2D B-mode parasternal long axis images. The algorithm is based on a deformable model of the septum and the mitral valve. The model shape is estimated using an extended Kalman filter. A feasibility study using 32 unselected recordings is presented. The recordings originate from a database consisting of subjects from a normal healthy population. Five patients with suspected hypertrophy were included in the study. Reference B-mode measurements were made by two cardiologists. A paired t-test revealed a non-significant mean difference, compared to the B-mode reference, of (mean±SD) 0.14±1.36 mm (p=0.532). Pearson's correlation coefficient was 0.79 (p<0.001). The results are comparable to the variability between the two cardiologists, which was found to be 1.29±1.23 mm (p<0.001). The results indicate that the method has potential as a tool for rapid assessment of IVSd. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  11. Hierarchical prediction errors in midbrain and septum during social learning

    Science.gov (United States)

    Mathys, Christoph; Weber, Lilian A. E.; Kasper, Lars; Mauer, Jan; Stephan, Klaas E.

    2017-01-01

    Abstract Social learning is fundamental to human interactions, yet its computational and physiological mechanisms are not well understood. One prominent open question concerns the role of neuromodulatory transmitters. We combined fMRI, computational modelling and genetics to address this question in two separate samples (N = 35, N = 47). Participants played a game requiring inference on an adviser’s intentions whose motivation to help or mislead changed over time. Our analyses suggest that hierarchically structured belief updates about current advice validity and the adviser’s trustworthiness, respectively, depend on different neuromodulatory systems. Low-level prediction errors (PEs) about advice accuracy not only activated regions known to support ‘theory of mind’, but also the dopaminergic midbrain. Furthermore, PE responses in ventral striatum were influenced by the Met/Val polymorphism of the Catechol-O-Methyltransferase (COMT) gene. By contrast, high-level PEs (‘expected uncertainty’) about the adviser’s fidelity activated the cholinergic septum. These findings, replicated in both samples, have important implications: They suggest that social learning rests on hierarchically related PEs encoded by midbrain and septum activity, respectively, in the same manner as other forms of learning under volatility. Furthermore, these hierarchical PEs may be broadcast by dopaminergic and cholinergic projections to induce plasticity specifically in cortical areas known to represent beliefs about others. PMID:28119508

  12. [Medial septal region as a target for modulation of seizure discharges in the hippocampus in a model of acute temporal lobe epilepsy].

    Science.gov (United States)

    Kichigina, V F; Butuzova, M V; Sinel'nikova, V V

    2007-01-01

    Investigation of changes in the hippocampal EEG produced by GABAergic and cholinergic substances delivered into the medial septum region was performed in awake rabbits. Changes in the threshold of seizure discharges in the hippocampus evoked by perforant path stimulation (model of acute epilepsy) were also examined. Injections of GABAA receptor antagonist picrotoxin or agonist of cholinergic receptors carbacholine in low doses induced an increase in the power of delta- and theta modulation and appearance of 7-12-Hz oscillations. The threshold of hippocampal seizure afterdischarges decreased. In higher doses, these substances evoked 7-15-Hz oscillations followed by seizures. GABAA receptor agonist muscimol and muscarinic receptor antagonist scopolamine decreased the power of the theta rhythm and increased the seizure threshold. Picrotoxin or carbacholine injected after muscimol or scopolamine, respectively, did not evoke seizures. Thus, we have shown the possibility to control hippocampal activity by local changes in the GABAergic and cholinergic systems of the medial septum region.

  13. Neuroanatomy and sex differences of the lordosis-inhibiting system in the lateral septum

    Science.gov (United States)

    Tsukahara, Shinji; Kanaya, Moeko; Yamanouchi, Korehito

    2014-01-01

    Female sexual behavior in rodents, termed lordosis, is controlled by facilitatory and inhibitory systems in the brain. It has been well demonstrated that a neural pathway from the ventromedial hypothalamic nucleus (VMN) to the midbrain central gray (MCG) is essential for facilitatory regulation of lordosis. The neural pathway from the arcuate nucleus to the VMN, via the medial preoptic nucleus, in female rats mediates transient suppression of lordosis, until female sexual receptivity is induced. In addition to this pathway, other regions are involved in inhibitory regulation of lordosis in female rats. The lordosis-inhibiting systems exist not only in the female brain but also in the male brain. The systems contribute to suppression of heterotypical sexual behavior in male rats, although they have the potential ability to display lordosis. The lateral septum (LS) exerts an inhibitory influence on lordosis in both female and male rats. This review focuses on the neuroanatomy and sex differences of the lordosis-inhibiting system in the LS. The LS functionally and anatomically links to the MCG to exert suppression of lordosis. Neurons of the intermediate part of the LS (LSi) serve as lordosis-inhibiting neurons and project axons to the MCG. The LSi-MCG neural connection is sexually dimorphic, and formation of the male-like LSi-MCG neural connection is affected by aromatized testosterone originating from the testes in the postnatal period. The sexually dimorphic LSi-MCG neural connection may reflect the morphological basis of sex differences in the inhibitory regulation of lordosis in rats. PMID:25278832

  14. Metabolic activation of amygdala, lateral septum and accumbens circuits during food anticipatory behavior.

    Science.gov (United States)

    Olivo, Diana; Caba, Mario; Gonzalez-Lima, Francisco; Rodríguez-Landa, Juan F; Corona-Morales, Aleph A

    2017-01-01

    When food is restricted to a brief fixed period every day, animals show an increase in temperature, corticosterone concentration and locomotor activity for 2-3h before feeding time, termed food anticipatory activity. Mechanisms and neuroanatomical circuits responsible for food anticipatory activity remain unclear, and may involve both oscillators and networks related to temporal conditioning. Rabbit pups are nursed once-a-day so they represent a natural model of circadian food anticipatory activity. Food anticipatory behavior in pups may be associated with neural circuits that temporally anticipate feeding, while the nursing event may produce consummatory effects. Therefore, we used New Zealand white rabbit pups entrained to circadian feeding to investigate the hypothesis that structures related to reward expectation and conditioned emotional responses would show a metabolic rhythm anticipatory of the nursing event, different from that shown by structures related to reward delivery. Quantitative cytochrome oxidase histochemistry was used to measure regional brain metabolic activity at eight different times during the day. We found that neural metabolism peaked before nursing, during food anticipatory behavior, in nuclei of the extended amygdala (basolateral, medial and central nuclei, bed nucleus of the stria terminalis), lateral septum and accumbens core. After pups were fed, however, maximal metabolic activity was expressed in the accumbens shell, caudate, putamen and cortical amygdala. Neural and behavioral activation persisted when animals were fasted by two cycles, at the time of expected nursing. These findings suggest that metabolic activation of amygdala-septal-accumbens circuits involved in temporal conditioning may contribute to food anticipatory activity. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Diagonal invariant ideals of Toeplitz algebras on discrete groups

    Institute of Scientific and Technical Information of China (English)

    许庆祥

    2002-01-01

    Diagonal invariant ideals of Toeplitz algebras defined on discrete groups are introduced and studied. In terms of isometric representations of Toeplitz algebras associated with quasi-ordered groups, a character of a discrete group to be amenable is clarified. It is proved that when G is Abelian, a closed two-sided non-trivial ideal of the Toeplitz algebra defined on a discrete Abelian ordered group is diagonal invariant if and only if it is invariant in the sense of Adji and Murphy, thus a new proof of their result is given.

  16. Diagonal Limit for Conformal Blocks in d Dimensions

    CERN Document Server

    Hogervorst, Matthijs; Rychkov, Slava

    2013-01-01

    Conformal blocks in any number of dimensions depend on two variables z, zbar. Here we study their restrictions to the special "diagonal" kinematics z = zbar, previously found useful as a starting point for the conformal bootstrap analysis. We show that conformal blocks on the diagonal satisfy ordinary differential equations, third-order for spin zero and fourth-order for the general case. These ODEs determine the blocks uniquely and lead to an efficient numerical evaluation algorithm. For equal external operator dimensions, we find closed-form solutions in terms of finite sums of 3F2 functions.

  17. Diagonally loaded SMI algorithm based on inverse matrix recursion

    Institute of Scientific and Technical Information of China (English)

    Cao Jianshu; Wang Xuegang

    2007-01-01

    The derivation of a diagonally loaded sample-matrix inversion (LSMI) algorithm on the busis of inverse matrix recursion (i.e. LSMI-IMR algorithm) is conducted by reconstructing the recursive formulation of covariance matrix. For the new algorithm, diagonal loading is by setting initial inverse matrix without any addition of computation. In addition, acorresponding improved recursive algorithm is presented, which is low computational complexity. This eliminates the complex multiplications of the scalar coefficient and updating matrix, resulting in significant computational savings.Simulations show that the LSMI-IMR algorithm is valid.

  18. Benchmarking Compressed Sensing, Super-Resolution, and Filter Diagonalization

    CERN Document Server

    Markovich, Thomas; Sanders, Jacob N; Aspuru-Guzik, Alan

    2015-01-01

    Signal processing techniques have been developed that use different strategies to bypass the Nyquist sampling theorem in order to recover more information than a traditional discrete Fourier transform. Here we examine three such methods: filter diagonalization, compressed sensing, and super-resolution. We apply them to a broad range of signal forms commonly found in science and engineering in order to discover when and how each method can be used most profitably. We find that filter diagonalization provides the best results for Lorentzian signals, while compressed sensing and super-resolution perform better for arbitrary signals.

  19. [Study on the correlation between chronic sinusitis with nasal septum deviation].

    Science.gov (United States)

    Ji, Xiaoqing; Fu, Hongjuan; Song, Aiqin

    2015-06-01

    Study on the correlation between chronic sinusitis with nasal septum deviation. Randomly selected 722 patients with coronal sinuses CT, statistics the number of cases of nasal septum deviation, cases of nasal septum deviation with chronic sinusitis, the wide and narrow side cases of nasal septum deviation complicated with sinusitis. The number of sinusitis without deviation, and paired test. The incidence of sinusitis between deviation of nasal septum and non deviation were 54. 13% and 44. 66%, the difference between two groups was statistically significant (Psinusitis with nasal septum deviation of wide and narrow side were 31. 65% and 32. 12%, no significant difference between the two groups (P>0. 01). The incidence of sinusitis high deviation and non high deviation were 59. 54% and 46. 97%, the difference between the two groups was statistically significant (Psinusitis was 54, the narrow side was 66, there is no significant difference between the two groups (P>0. 05). The deviation of nasal septum is associated with the formation of chronic sinusitis, the high deviation is more prone to sinusitis, The incidence of sinusitis and nasal septum deviation on both sides was no different.

  20. [Coronary circulation in asymmetrical hypertrophy of the interventricular septum. On a new pathogenic hypothesis].

    Science.gov (United States)

    Sánchez, G; Orea, A; Trevethan, S; Martínez Ríos, M A

    1984-01-01

    Thirty-four patients with left ventricular hypertrophy were studied. In all cases the following parameters were analyzed: 1) Echocardiography:left ventricular diastolic and systolic diameters, ejection fraction, thickness and movement of interventricular septum and posterior wall of the left ventricle (LV) 2) Electrocardiography: R wave voltaje in precordial leads V2, V3 and V5 and electrical axis in frontal plane 3) Catheterization: intracavitary pressures in LV and aortic pressures 4) Left ventriculography: areas of altered contractility 5) Coronariography: distribution pattern of coronary arteries and number of first order branches of circumflex (CA) and anterior descending coronary arteries (ADCA). The population was divided into 2 groups. Group A (GA) was made up of 22 patients with concentric hypertrophy (CH) of the LV (15 with systemic hypertensive heart disease, 6 with aortic valvular stenosis and 1 idiopathic). Echocardiographic findings included posterior wall thickness (PWT) or septal thickness of 1.1. cm or more and interventricular septum-posterior wall thickness ratio (S/PW) of less than 1.3. Group B (GB) included 12 patients with asymmetric septal hypertrophy (ASH), idiopathic in 5, systemic hypertensive heart disease in 4 and aortic valvular stenosis in 3. In these patients the S/PW thickness ratio was greater than 1.3 and the thickness of either wall greater than 1.1. cm. When the data of the two groups were compared there were significant differences in relation to the presence of septal hypertrophy. The R wave voltage in V2, interventricular thickness and S/PW were greater in GB. In addition, septal movement was less in GB than in Group A (0.47 +/- 0.26 cm vs. 0.74 +/- 0.37 cm; P less than 0.05). PWT was also less in Group B than in A (B: 1.01 +/- 0.1 cm, A: 1.2 +/- 0.2 cm; P less than 0.001). The CA in Group B divided into fewer than 4 first order branches to the upper two thirds of the posterior and lateral walls of the LV in 91.6%. This

  1. Stray Field Reduction in ALS Eddy Current Septum Magnets

    CERN Document Server

    Shuman, Derek; Prestemon, Soren; Schlüter, Ross D; Steier, Christoph; Stover, Gregory D

    2005-01-01

    Stray field from an eddy current septum magnet adversely affects the circulating beam and can be reduced using several techniques. The stray field time history typically has a fast rise section followed by a long exponential decay section when pulsed with a half sine drive current. Changing the drive current pulse to a full sine has the effect of both reducing peak stray field magnitude by ~3x, and producing a quick decay from this peak to a lower field level which then has a similar long decay time constant as that from the half sine only drive current pulse. A method for tuning the second half sine (reverse) drive current pulse to eliminate the long exponential decay section is given.

  2. Management of Recurrent Stricture Formation after Transverse Vaginal Septum Excision

    Directory of Open Access Journals (Sweden)

    Ridhima Gupta

    2015-01-01

    Full Text Available Background. A transverse vaginal septum (TVS is a rare obstructing anomaly, caused due to improper fusion of Müllerian ducts and urogenital sinus during embryogenesis. Case. A 15-year-old girl presented with primary amenorrhea. She had multiple congenital anomalies. Initial examination and imaging investigation revealed the presence of a unicornuate uterus and a TVS. The TVS was excised; however the patient was unable to perform vaginal dilation postoperatively leading to recurrent stricture formation. She underwent multiple surgeries for excision of the stricture. The patient was eventually evaluated every day in the clinic until she was able to demonstrate successful vaginal dilatation in the presence of a clinician. Summary and Conclusion. Properly guided regular and intensive vaginal dilation after TVS excision may decrease the need of reoperations due to recurrent stricture formation.

  3. Management of Recurrent Stricture Formation after Transverse Vaginal Septum Excision.

    Science.gov (United States)

    Gupta, Ridhima; Bozzay, Joseph D; Williams, David L; DePond, Robert T; Gantt, Pickens A

    2015-01-01

    Background. A transverse vaginal septum (TVS) is a rare obstructing anomaly, caused due to improper fusion of Müllerian ducts and urogenital sinus during embryogenesis. Case. A 15-year-old girl presented with primary amenorrhea. She had multiple congenital anomalies. Initial examination and imaging investigation revealed the presence of a unicornuate uterus and a TVS. The TVS was excised; however the patient was unable to perform vaginal dilation postoperatively leading to recurrent stricture formation. She underwent multiple surgeries for excision of the stricture. The patient was eventually evaluated every day in the clinic until she was able to demonstrate successful vaginal dilatation in the presence of a clinician. Summary and Conclusion. Properly guided regular and intensive vaginal dilation after TVS excision may decrease the need of reoperations due to recurrent stricture formation.

  4. Early depictions of the human anterior nasal septum.

    Science.gov (United States)

    Pirsig, Wolfgang; Sokiranski, Roman

    2006-06-01

    In the literature, remarks on the depiction of the anterior nasal septum in prehistoric times cannot be found. Studying works of art from some archaeological sites of Asia, Asia Minor, Near East, Egypt, and Southeastern Europe the anatomical depiction of the columella and the nostrils in human figures are shown. These figures or heads, partly appearing as masks, were made of ivory, stone, marble, terracotta, steatite, reeds and clay, or of burned limestone. Faces and figures sculpted in the time between the Upper Palaeolithic (30,000 - 25,000 BC) and the Early Bronze Age (3,300 - 2,400 BC) are presented as examples of our ancestors' outstanding skill to create works of art with an astonishing ability to observe anatomical details. The tendency to create a human nose in a natural manner can already be recognized in the figurines of the Upper Palaeolithic.

  5. Diagonalization of bosonic quadratic Hamiltonians by Bogoliubov transformations

    DEFF Research Database (Denmark)

    Nam, Phan Thanh; Napiorkowski, Marcin; Solovej, Jan Philip

    2016-01-01

    We provide general conditions for which bosonic quadratic Hamiltonians on Fock spaces can be diagonalized by Bogoliubov transformations. Our results cover the case when quantum systems have infinite degrees of freedom and the associated one-body kinetic and paring operators are unbounded. Our...

  6. Penguins and Pandas: A Note on Teaching Cantor's Diagonal Argument

    Science.gov (United States)

    Rauff, James V.

    2008-01-01

    Cantor's diagonal proof that the set of real numbers is uncountable is one of the most famous arguments in modern mathematics. Mathematics students usually see this proof somewhere in their undergraduate experience, but it is rarely a part of the mathematical curriculum of students of the fine arts or humanities. This note describes contexts that…

  7. Convergence of GAOR Iterative Method with Strictly Diagonally Dominant Matrices

    Directory of Open Access Journals (Sweden)

    Guangbin Wang

    2011-01-01

    Full Text Available We discuss the convergence of GAOR method for linear systems with strictly diagonally dominant matrices. Moreover, we show that our results are better than ones of Darvishi and Hessari (2006, Tian et al. (2008 by using three numerical examples.

  8. Why the South Pacific Convergence Zone is diagonal

    Science.gov (United States)

    van der Wiel, Karin; Matthews, Adrian J.; Joshi, Manoj M.; Stevens, David P.

    2016-03-01

    During austral summer, the majority of precipitation over the Pacific Ocean is concentrated in the South Pacific Convergence Zone (SPCZ). The surface boundary conditions required to support the diagonally (northwest-southeast) oriented SPCZ are determined through a series of experiments with an atmospheric general circulation model. Continental configuration and orography do not have a significant influence on SPCZ orientation and strength. The key necessary boundary condition is the zonally asymmetric component of the sea surface temperature (SST) distribution. This leads to a strong subtropical anticyclone over the southeast Pacific that, on its western flank, transports warm moist air from the equator into the SPCZ region. This moisture then intensifies (diagonal) bands of convection that are initiated by regions of ascent and reduced static stability ahead of the cyclonic vorticity in Rossby waves that are refracted toward the westerly duct over the equatorial Pacific. The climatological SPCZ is comprised of the superposition of these diagonal bands of convection. When the zonally asymmetric SST component is reduced or removed, the subtropical anticyclone and its associated moisture source is weakened. Despite the presence of Rossby waves, significant moist convection is no longer triggered; the SPCZ disappears. The diagonal SPCZ is robust to large changes (up to ±6 °C) in absolute SST (i.e. where the SST asymmetry is preserved). Extreme cooling (change <-6 °C) results in a weaker and more zonal SPCZ, due to decreasing atmospheric temperature, moisture content and convective available potential energy.

  9. Thermodynamics of Rh nuclear spins calculated by exact diagonalization

    DEFF Research Database (Denmark)

    Lefmann, K.; Ipsen, J.; Rasmussen, F.B.;

    2000-01-01

    We have employed the method of exact diagonalization to obtain the full-energy spectrum of a cluster of 16 Rh nuclear spins, having dipolar and RK interactions between first and second nearest neighbours only. We have used this to calculate the nuclear spin entropy, and our results at both positive...

  10. Green function diagonal for a class of heat equations

    CERN Document Server

    Kwiatkowski, Grzegorz

    2011-01-01

    A construction of the heat kernel diagonal is considered as element of generalized Zeta function, that, being meromorfic function, its gradient at the origin defines determinant of a differential operator in a technique for regularizing quadratic path integral. Some classes of explicit expression in the case of finite-gap potential coefficient of the heat equation are constructed.

  11. Diagonalization of bosonic quadratic Hamiltonians by Bogoliubov transformations

    DEFF Research Database (Denmark)

    Nam, Phan Thanh; Napiorkowski, Marcin; Solovej, Jan Philip

    2016-01-01

    We provide general conditions for which bosonic quadratic Hamiltonians on Fock spaces can be diagonalized by Bogoliubov transformations. Our results cover the case when quantum systems have infinite degrees of freedom and the associated one-body kinetic and paring operators are unbounded. Our...

  12. Penile torsion correction by diagonal corporal plication sutures

    Directory of Open Access Journals (Sweden)

    Brent W. Snow

    2009-02-01

    Full Text Available Penile torsion is commonly encountered. It can be caused by skin and dartos adherence or Buck’s fascia attachments. The authors suggest a new surgical approach to solve both problems. If Buck’s fascia involvement is demonstrated by artificial erection then a new diagonal corporal plication suture is described to effectively solve this problem.

  13. Tamil Nadu and the Diagonal Divide in Sex Ratios

    NARCIS (Netherlands)

    A.S. Bedi (Arjun Singh); S. Srinivasan (Sharada)

    2009-01-01

    textabstractBetween 1961 and 2001, India’s 0-6 sex ratio has steadily declined. Despite evidence to the contrary, this ratio is often characterised in terms of a diagonal divide with low 0-6 sex ratios in northern and western India and normal 0-6 sex ratios in eastern and southern India. While unexp

  14. Consenso SECOT artrosis femorotibial medial.

    OpenAIRE

    A. Moreno; Silvestre Muñoz, Antonio; Carpintero, P.

    2013-01-01

    Se presenta un consenso elaborado por SECOT sobre la actuación en la artrosis del compartimento medial de la rodilla para establecer criterios y recomendaciones clínicas orientadas a unificar criterios en su manejo, abordando los factores implicados en la patogenia de la artrosis femorotibial medial de rodilla, la utilidad de las técnicas diagnósticas por la imagen y la utilidad de la artroscopia. También se analizarán los tratamientos conservadores y el tratamiento quirúrgico. Los expertos c...

  15. Injerto libre braquial medial Free medial arm graft

    Directory of Open Access Journals (Sweden)

    P. Martos Díaz

    2007-12-01

    Full Text Available Introducción. Entre las reconstrucciones de defectos titulares de cabeza y cuello, el injerto libre microvascularizado braquial medial no ha adquirido mucha popularidad debido a las variaciones anatómicas que se reflejan en la vascularización de éste. Nuestro objetivo es realizar una descripción de la anatomía y técnica quirúrgica, así como una revisión de la literatura describiendo las ventajas y desventajas de este tipo de injerto. Material y método. Presentamos el caso de una paciente con carcinoma epidermoide de mucosa yugal izquierda con afectación ganglionar ipsilateral. Se procedió a su resección con márgenes más disección cervical funcional. La reconstrucción del defecto se llevó a cabo mediante un injerto libre microvascularizado braquial medial de brazo izquierdo. Discusión. Pensamos que el injerto libre braquial medial de brazo se trata de una opción más segura a la hora de la reconstrucción de defectos cervicofaciales, aportando una serie de ventajas entre las que destacan: no sacrificio de una arteria terminal, cierre primario de la zona donante, mínimo defecto estético, y poseer una piel fina, elástica y sin vello.Introduction. Free medial microvascularized arm grafts have not become very popular for the reconstruction of head and neck defects due to anatomic variations in their vascularization. Our objective was to describe the anatomy and surgical technique and to review the literature on the advantages and disadvantages of free medial arm grafts. Material and methods. We report the case of a patient with squamous cell carcinoma of the left jugal mucosa with same-side lymph node involvement. The tumor was resected with margins and a functional cervical dissection was performed. The defect was reconstructed using a free medial microvascularized graft from the left arm. Discussion. We believe that free medial arm grafts are a safer option for the reconstruction of cervicofacial defects and that they offer

  16. Impedance studies of the dummy septum for CERN PS multi-turn extraction

    CERN Document Server

    Persichelli, S; Berrig, O; Herbst, J; Kuczerowski, J; Giovannozzi, M; Salvant, B

    2014-01-01

    A protection septum has been installed in the CERN PS section 15 in order to mitigate irradiation of the magnetic septum 16 for fast extractions towards the SPS. Impedance studies have been performed, showing that beams circulating in the septum during extraction generate sharp resonances in the coupling impedance. Impedance measurements with the wire technique have been performed, showing a good agreement with simulations. Instability rise times of trapped modes have been evaluated and compared to extraction duration. Solutions for reducing the impact on the stability of the beam have been considered

  17. Non-diagonal four-dimensional cohomogeneity-one Einstein metrics in various signatures

    CERN Document Server

    Dunajski, Maciej

    2016-01-01

    Most known four-dimensional cohomogeneity-one Einstein metrics are diagonal in the basis defined by the left-invariant one-forms, though some essentially non-diagonal ones are known. We consider the problem of explicitly seeking non-diagonal Einstein metrics, and we find solutions which in some cases exhaust the possibilities. In particular we construct new examples of neutral signature non--diagonal Bianchi type VIII Einstein metrics with self--dual Weyl tensor.

  18. Diagonal multi-soliton matrix elements in finite volume

    CERN Document Server

    Pálmai, T

    2012-01-01

    We consider diagonal matrix elements of local operators between multi-soliton states in finite volume in the sine-Gordon model, and formulate a conjecture regarding their finite size dependence which is valid up to corrections exponential in the volume. This conjecture extends the results of Pozsgay and Tak\\'acs which were only valid for diagonal scattering. In order to test the conjecture we implement a numerical renormalization group improved truncated conformal space approach. The numerical comparisons confirm the conjecture, which is expected to be valid for general integrable field theories. The conjectured formula can be used to evaluate finite temperature one-point and two-point functions using recently developed methods.

  19. Natures of Rotating Stall Cell in a Diagonal Flow Fan

    Institute of Scientific and Technical Information of China (English)

    N. SHIOMI; K. KANEKO; T. SETOGUCHI

    2005-01-01

    In order to clarify the natures of a rotating stall cell, the experimental investigation was carried out in a high specific-speed diagonal flow fan. The pressure field on the casing wall and the velocity fields at the rotor inlet and outlet were measured under rotating stall condition with a fast response pressure transducer and a single slant hot-wire probe, respectively. The data were processed using the "Double Phase-Locked Averaging (DPLA)"technique, which enabled to obtain the unsteady flow field with a rotating stall cell in the relative co-ordinate system fixed to the rotor. As a result, the structure and behavior of the rotating stall cell in a high specific-speed diagonal flow fan were shown.

  20. Block-bordered diagonalization and parallel iterative solvers

    Energy Technology Data Exchange (ETDEWEB)

    Alvarado, F.; Dag, H.; Bruggencate, M. ten [Univ. of Wisconsin, Madison, WI (United States)

    1994-12-31

    One of the most common techniques for enhancing parallelism in direct sparse matrix methods is the reorganization of a matrix into a blocked-bordered structure. Incomplete LDU factorization is a very good preconditioner for PCG in serial environments. However, the inherent sequential nature of the preconditioning step makes it less desirable in parallel environments. This paper explores the use of BBD (Blocked Bordered Diagonalization) in connection with ILU preconditioners. The paper shows that BBD-based ILU preconditioners are quite amenable to parallel processing. Neglecting entries from the entire border can result in a blocked diagonal matrix. The result is a great increase in parallelism at the expense of additional iterations. Experiments on the Sequent Symmetry shared memory machine using (mostly) power system that matrices indicate that the method is generally better than conventional ILU preconditioners and in many cases even better than partitioned inverse preconditioners, without the initial setup disadvantages of partitioned inverse preconditioners.

  1. Off-diagonal Bethe ansatz for exactly solvable models

    CERN Document Server

    Wang, Yupeng; Cao, Junpeng; Shi, Kangjie

    2015-01-01

    This book serves as an introduction of the off-diagonal Bethe Ansatz method, an analytic theory for the eigenvalue problem of quantum integrable models. It also presents some fundamental knowledge about quantum integrability and the algebraic Bethe Ansatz method. Based on the intrinsic properties of R-matrix and K-matrices, the book introduces a systematic method to construct operator identities of transfer matrix.  These identities allow one to establish the inhomogeneous T-Q relation formalism to obtain Bethe Ansatz equations and to retrieve corresponding eigenstates. Several longstanding models can thus be solved via this method since the lack of obvious reference states is made up. Both the exact results and the off-diagonal Bethe Ansatz method itself may have important applications in the fields of quantum field theory, low-dimensional condensed matter physics, statistical physics and cold atom systems.

  2. GEAR CRACK EARLY DIAGNOSIS USING BISPECTRUM DIAGONAL SLICE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A study of bispectral analysis in gearbox condition monitoring is presented.The theory of bispectrum and quadratic phase coupling (QPC) is first introduced, and then equations for computing bispectrum slices are obtained.To meet the needs of online monitoring, a simplified method of computing bispectrum diagonal slice is adopted.Industrial gearbox vibration signals measured from normal and tooth cracked conditions are analyzed using the above method.Experiments results indicate that bispectrum can effectively suppress the additive Gaussian noise and chracterize the QPC phenomenon.It is also shown that the 1-D bispectrum diagonal slice can capture the non-Gaussian and nonlinear feature of gearbox vibration when crack occurred, hence, this method can be employed to gearbox real time monitoring and early diagnosis.

  3. Strong Linear Correlation Between Eigenvalues and Diagonal Matrix Elements

    CERN Document Server

    Shen, J J; Zhao, Y M; Yoshinaga, N

    2008-01-01

    We investigate eigenvalues of many-body systems interacting by two-body forces as well as those of random matrices. We find a strong linear correlation between eigenvalues and diagonal matrix elements if both of them are sorted from the smaller values to larger ones. By using this linear correlation we are able to predict reasonably all eigenvalues of given shell model Hamiltonian without complicated iterations.

  4. Diagonalization and representation results for nonpositive sesquilinear form measures

    Science.gov (United States)

    Hytönen, Tuomas; Pellonpää, Juha-Pekka; Ylinen, Kari

    2008-02-01

    We study decompositions of operator measures and more general sesquilinear form measures E into linear combinations of positive parts, and their diagonal vector expansions. The underlying philosophy is to represent E as a trace class valued measure of bounded variation on a new Hilbert space related to E. The choice of the auxiliary Hilbert space fixes a unique decomposition with certain properties, but this choice itself is not canonical. We present relations to Naimark type dilations and direct integrals.

  5. The Diagonal Compression Field Method using Circular Fans

    DEFF Research Database (Denmark)

    Hansen, Thomas

    2005-01-01

    This paper presents a new design method, which is a modification of the diagonal compression field method, the modification consisting of the introduction of circular fan stress fields. The traditional method does not allow changes of the concrete compression direction throughout a given beam...... fields may be used whenever changes in the concrete compression direction are desired. To illustrate the new design method, a specific example of a prestressed concrete beam is calculated....

  6. A method of diagonalization for sfermion mass matrices

    CERN Document Server

    Aranda, Alfredo; Noriega-Papaqui, R

    2009-01-01

    We present a method of diagonalization for the sfermion mass matrices of the minimal supersymmetric standard model (MSSM). It provides analytical expressions for the masses and mixing angles of rather general hermitian sfermion mass matrices, and allows the study of scenarios that extend the usual constrained - MSSM. Three signature cases are presented explicitly and a general study of flavor changing neutral current processes is outlined in the discussion.

  7. Efficient variational diagonalization of fully many-body localized Hamiltonians

    Science.gov (United States)

    Pollmann, Frank; Khemani, Vedika; Cirac, J. Ignacio; Sondhi, S. L.

    2016-07-01

    We introduce a variational unitary matrix product operator based variational method that approximately finds all the eigenstates of fully many-body localized one-dimensional Hamiltonians. The computational cost of the variational optimization scales linearly with system size for a fixed depth of the UTN ansatz. We demonstrate the usefulness of our approach by considering the Heisenberg chain in a strongly disordered magnetic field for which we compare the approximation to exact diagonalization results.

  8. The germinal zones of the basal ganglia but not the septum generate GABAergic interneurons for the cortex.

    Science.gov (United States)

    Rubin, Anna N; Alfonsi, Fabienne; Humphreys, Michael P; Choi, Christina K P; Rocha, Susana F; Kessaris, Nicoletta

    2010-09-08

    Cortical interneurons originate from subpallial precursors and migrate into the cortex during development. Using genetic lineage tracing in transgenic mice we examine the contribution of two germinal zones, the septum and the lateral ganglionic eminence/caudal ganglionic eminence (LGE/CGE) to interneurons of the cortex. We find that the septal neuroepithelium does not generate interneurons for the neocortex. There is, however, clear migration of cells from the LGE/CGE to the cortex. Comparison of the dynamics of cortical colonization by the two major cohorts of interneurons originating in the medial ganglionic eminence (MGE) and the LGE/CGE has shown differences in the timing of migration and initial route of entry into the cortex. LGE/CGE-derived interneurons enter the cortex later than the MGE-derived ones. They invade the cortex through the subventricular/intermediate zone route and only later disperse within the cortical plate and the marginal zone. During the first postnatal week MGE interneurons move extensively to acquire their laminar position within the cortical plate whereas LGE/CGE-derived cells remain largely within the upper layers of the cortex. The two populations intermingle in the adult cortex but have distinct neurochemical properties and different overall distributions. LGE/CGE-derived interneurons account for one third of the total GABAergic interneuron population in the adult cortex.

  9. Quantum Diagonalization Method in the TAVIS-CUMMINGS Model

    Science.gov (United States)

    Fujii, Kazuyuki; Higashida, Kyoko; Kato, Ryosuke; Suzuki, Tatsuo; Wada, Yukako

    2005-06-01

    To obtain the explicit form of evolution operator in the Tavis-Cummings model we must calculate the term ${e}^{-itg(S_{+}\\otimes a+S_{-}\\otimes a^{\\dagger})}$ explicitly which is very hard. In this paper we try to make the quantum matrix $A\\equiv S_{+}\\otimes a+S_{-}\\otimes a^{\\dagger}$ diagonal to calculate ${e}^{-itgA}$ and, moreover, to know a deep structure of the model. For the case of one, two and three atoms we give such a diagonalization which is first nontrivial examples as far as we know, and reproduce the calculations of ${e}^{-itgA}$ given in quant-ph/0404034. We also give a hint to an application to a noncommutative differential geometry. However, a quantum diagonalization is not unique and is affected by some ambiguity arising from the noncommutativity of operators in quantum physics. Our method may open a new point of view in Mathematical Physics or Quantum Physics.

  10. Optimized Paraunitary Filter Banks for Time-Frequency Channel Diagonalization

    Directory of Open Access Journals (Sweden)

    Ju Ziyang

    2010-01-01

    Full Text Available We adopt the concept of channel diagonalization to time-frequency signal expansions obtained by DFT filter banks. As a generalization of the frequency domain channel representation used by conventional orthogonal frequency-division multiplexing receivers, the time-frequency domain channel diagonalization can be applied to time-variant channels and aperiodic signals. An inherent error in the case of doubly dispersive channels can be limited by choosing adequate windows underlying the filter banks. We derive a formula for the mean-squared sample error in the case of wide-sense stationary uncorrelated scattering (WSSUS channels, which serves as objective function in the window optimization. Furthermore, an enhanced scheme for the parameterization of tight Gabor frames enables us to constrain the window in order to define paraunitary filter banks. We show that the design of windows optimized for WSSUS channels with known statistical properties can be formulated as a convex optimization problem. The performance of the resulting windows is investigated under different channel conditions, for different oversampling factors, and compared against the performance of alternative windows. Finally, a generic matched filter receiver incorporating the proposed channel diagonalization is discussed which may be essential for future reconfigurable radio systems.

  11. Optimized Paraunitary Filter Banks for Time-Frequency Channel Diagonalization

    Science.gov (United States)

    Ju, Ziyang; Hunziker, Thomas; Dahlhaus, Dirk

    2010-12-01

    We adopt the concept of channel diagonalization to time-frequency signal expansions obtained by DFT filter banks. As a generalization of the frequency domain channel representation used by conventional orthogonal frequency-division multiplexing receivers, the time-frequency domain channel diagonalization can be applied to time-variant channels and aperiodic signals. An inherent error in the case of doubly dispersive channels can be limited by choosing adequate windows underlying the filter banks. We derive a formula for the mean-squared sample error in the case of wide-sense stationary uncorrelated scattering (WSSUS) channels, which serves as objective function in the window optimization. Furthermore, an enhanced scheme for the parameterization of tight Gabor frames enables us to constrain the window in order to define paraunitary filter banks. We show that the design of windows optimized for WSSUS channels with known statistical properties can be formulated as a convex optimization problem. The performance of the resulting windows is investigated under different channel conditions, for different oversampling factors, and compared against the performance of alternative windows. Finally, a generic matched filter receiver incorporating the proposed channel diagonalization is discussed which may be essential for future reconfigurable radio systems.

  12. UNDERSTANDING OF PROSPECTIVE MATHEMATICS TEACHERS OF THE CONCEPT OF DIAGONAL

    Directory of Open Access Journals (Sweden)

    Ülkü Ayvaz

    2017-06-01

    Full Text Available This study aims to investigate the concept images of prospective mathematics teachers about the concept of diagonal.  With this aim, case study method was used in the study. The participants of the study were consisted of 7 prospective teachers educating at the Department of Mathematics Education. Criterion sampling method was used to select the participants and the criterion was determined as taking the course of geometry in the graduate program. Data was collected in two steps: a diagnostic test form about the definition and features of diagonal was applied to participants firstly and according to the answers of the participants to the diagnostic test form, semi-structured interviews were carried out. Data collected form the diagnostic test form and the semi-structured interviews were analyzed with descriptive analysis. According to the results of the study, it is understood that the prospective teachers had difficulties with the diagonals of parallelogram, rhombus and deltoid. Moreover, it is also seen that the prospective teachers were inadequate to support their ideas with further explanations although they could answer correctly. İt is thought that the inadequacy of the prospective teachers stems from the inadequacy related to proof.DOI: http://dx.doi.org/10.22342/jme.8.2.4102.165-184

  13. Quantum Diagonalization Method in the Tavis-Cummings Model

    CERN Document Server

    Fujii, K; Kato, R; Suzuki, T; Wada, Y; Fujii, Kazuyuki; Higashida, Kyoko; Kato, Ryosuke; Suzuki, Tatsuo; Wada, Yukako

    2004-01-01

    To obtain the explicit form of evolution operator in the Tavis-Cummings model we must calculate the term ${e}^{-itg(S_{+}\\otimes a+S_{-}\\otimes a^{\\dagger})}$ explicitly which is very hard. In this paper we try to make the quantum matrix $A\\equiv S_{+}\\otimes a+S_{-}\\otimes a^{\\dagger}$ diagonal to calculate ${e}^{-itgA}$ and, moreover, to know a deep structure of the model. For the case of one, two and three atoms we give such a diagonalization which is first nontrivial examples as far as we know, and reproduce the calculations of ${e}^{-itgA}$ given in quant-ph/0404034. We also give a hint to an application to a noncommutative differential geometry. However, a quantum diagonalization is not unique and is affected by some ambiguity arising from the noncommutativity of operators in quantum physics. Our method may open a new point of view in Mathematical Physics or Quantum Physics.

  14. SEPTUM MAGNET DESIGN FOR THE APS-U

    Energy Technology Data Exchange (ETDEWEB)

    Abliz, M.; Jaski, M.; Xiao, A.; Wienands, U.; Cease, H.; Borland, M.; Decker, G.; Kerby, J.

    2017-06-25

    The Advanced Photon Source is in the process of upgrading its storage ring from a double-bend to a multi-bend lattice as part of the APS Upgrade Project (APS-U). A swap-out injection scheme is planned for the APS-U to keep a constant beam current and to enable a small dynamic aperture. A septum magnet with a minimum thickness of 2 mm and an injection field of 1.06 T has been designed, delivering the required total deflecting angle is 89 mrad with a ring energy of 6 GeV. The stored beam chamber has an 8 mm x 6 mm super-ellipsoidal aperture. The magnet is straight; however, it is tilted in yaw, roll, and pitch from the stored beam chamber to meet the on axis swap out injection requirements for the APS-U lattice. In order to minimize the leakage field inside the stored beam chamber, four different techniques were utilized in the design. As a result, the horizontal deflecting angle of the stored beam was held to only 5 µrad, and the integrated skew quadrupole inside the stored beam chamber was held to 0.09 T. The detailed techniques that were applied to the design, field multipoles, and resulting trajectories of the injected and stored beams are reported.

  15. Eddy current septum magnets for injection and extraction at SSRF

    Science.gov (United States)

    Ouyang, Lian-Hua; Gu, Ming; Liu, Bo; Chen, Rong

    2010-03-01

    There are 6 in-vacuum eddy current septum magnets used for booster injection, extraction, and storage ring injection in SSRF. Special attention was paid to coils and their support designs because of the shock force they bear in the magnetic fields and the high heat which is hard to be dissipated in vacuum environment. For the storage ring magnets, good transverse homogeneity in the gap was achieved by careful design, precise machining and accurate assembly; and an extremely low leakage field on the stored beam is another key feature thanks to the high permeability Mu metal. Magnetic field measurement was conducted with both a point coil and a long integral coil, and the results agree well with the OPERA-2d/3d simulations. An inner tube is added to keep the continuity of impedance for the circulating beam with two RF finger flanges at each end. There is no vacuum separation between the inner tube and the magnet chamber. Sputter ion pumps integrated with NEG are used to acquire the UHV for the chamber.

  16. Development of an Eddy Current Septum for LINAC4

    CERN Document Server

    Barnes, M; Borburgh, J; Fowler, T; Goddard, B; Ueda, A; Weterings, W

    2008-01-01

    A linear accelerator (linac) is the first stage of the CERN accelerator complex. The linac defines the beam quality for subsequent stages of acceleration and the reliability has to be high as a fault of the linac shuts down all other machines. The existing linacs at CERN were designed 30 or more years ago: recent upgrades allowed the linacs to reach LHC requirements but also showed that they are at the limit of their brightness and intensity capabilities. A replacement Superconducting Proton Linac (SPL) has been proposed; the initial part of the SPL is termed LINAC4. The LINAC4 injection bump would be made up of a set of four pulsed dipole magnets; the first of these magnets (BS1) must act as a septum with a thin element dividing the high-field region of the circulating beam from the field-free region through which injected $H^{-}$ beam must pass. The initial specifications for BS1 required; a deflection of 66 mrad at 160 MeV, achieved with a peak field of 628 mT and a length of 250 mm: the field fall time wa...

  17. Ruptura del septum ventricular post infarto agudo del miocardio

    Directory of Open Access Journals (Sweden)

    Warner Rodríguez Jerez

    2003-08-01

    Full Text Available La ruptura del septum interventricular (CIV es una complicación grave del infarto agudo del miocardio y tiene un alto índice de mortalidad. El diagnóstico rápido, medidas adecuadas en el manejo médico como el uso de balón de contrapulsación intra aórtico y la corrección quirúrgica pronta son algunos de los esfuerzos que se han realizado para mejorar la sobrevida y disminuir el tiempo de recuperación de los pacientes, posterior a un evento de este tipo. Dentro de los factores de riesgo para la comunicación interventricular post infarto destacan la edad avanzada, sexo femenino, el infarto de cara anterior, y la ausencia de tabaquismo. En este artículo se presenta el caso de una paciente de la Unidad Coronaria del Hospital San Juan de Dios y se hace revisión del tema.

  18. Successful treatment of two cases of urorectal septum malformation sequence with oligohydramnios and severe respiratory failure

    Directory of Open Access Journals (Sweden)

    Sekiguchi K

    2013-03-01

    Full Text Available Kazuhito Sekiguchi, Daijiro Takahashi, Takehiko Hiroma, Tomohiko Nakamura Division of Neonatology, Nagano Children's Hospital, Nagano, Japan Abstract: Urorectal septum malformation sequence can be diagnosed prenatally. We report herein the successful treatment of severe respiratory failure in two patients with urorectal septum malformation sequence and prenatally diagnosed oligohydramnios. The patients showed significant hypoxic deterioration and persistent pulmonary artery hypertension soon after birth. We used high-frequency ventilation (HFO, nitric oxide (NO, and extracorporeal membrane oxygenation (ECMO. The patients were successfully weaned from ECMO and artificial ventilation and discharged to home. Although termination of the pregnancy has often been selected for fetuses with oligohydramnios-related urorectal septum malformation sequence, our results suggest the opportunity for these fetuses to be treated using respiratory supports including HFO, NO, and ECMO after birth. Keywords: urorectal septum malformation sequence, oligohydramnios, pulmonary hypoplasia

  19. The case of a cyst hydatid localized within the interatrial septum.

    Science.gov (United States)

    Karabay, Ozalp; Onen, Ahmet; Yildiz, Fidan; Yilmaz, Erkan; Erdal, Cenk A; Sanli, Aydin; Kilci, Göksel; Algin, Ibrahim; Itil, Oya; Açikel, Unal

    2004-07-01

    The ratio of cardiac involvement of Echinoccocus granulosus is 0.02-2% and although seen rarely, involvement of the interatrial septum has also been reported in the published literature. The present case was a 19-year-old male university student admitted to hospital with complaints of headache and dizziness. Computerized tomography of the cranium revealed a cystic mass located at the frontal region and enucleation of the cyst was performed during surgery. A cystic lesion 5 x 4 cm in size was detected within the interatrial septum on two-dimensional transthoracic echocardiography during the postoperative period and the patient was referred to our clinic. Open heart surgery was performed and a hydatid cyst that involved the interatrial septum was enucleated. The cyst wall was sutured to the interatrial septum. No complications developed during the postoperative period. The patient was discharged on the fifth day of hospitalization and medical therapy was started with albendazole.

  20. Clinical and pathological characteristics of septum pellucidum tumor and choice of surgical approaches for its resection

    Institute of Scientific and Technical Information of China (English)

    WANG Lei; ZHANG Mao-zhi; ZHANG Wei; ZHAO Shang-feng; ZHAO Ji-zong; JIA Jin-xiu

    2005-01-01

    Background Tumor involving the septum pellucidum is uncommon. Surgery as the main therapeutic procedure for this lesion is a challenge to neurosurgeons. We analyzed the clinical characteristics and pathological features of septum pellucidum tumor in 41 patients and compared the curative effects of frontal transcortical, trans-sulcal and interhemispheric transcallosal approaches. Methods Clinical characteristics and the pathological features of septum pellucidum tumor were investigated retrospectively in 41 patients. The differences in postoperative residual rates, extents of tumors and resection of normal brain tissues after use of the three approaches in these patients were analyzed statistically. Results Septum pellucidum tumor is more likely to attack young or middle-aged persons. The tumor mainly presents itself as a central neurocytoma or cerebral low-grade glioma in pathology and manifests as intracranial hypertension clinically. No difference was found in the extent of tumor resection but significant difference in the extent of normal brain tissue resection and in postoperative disability rate among the three approaches. The transcortical approach brought about the most serious injury to brain tissue and the highest disability rate, Whereas the frontal transcallosal approach the lightest injury and the lowest disability rate. The injury to brain tissue and the disability rate brought about by the front trans-sulcus approach were between the above two approaches. Conclusions Operation is still regarded the major treatment for septum pellucidum tumor. Transcallosal and trans-sulcus approaches are fit with the concept of minimally invasive surgery, and transcallosal approach is the first choice for septum pellucidum tumor.

  1. High signal intensity of the septum pellucidum at MR imaging; Significance in hydrocephalus

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Jeong Hee; Kim, Eun Ha; Chung, Chun Phil; Kim, Chang Soo [Maryknoll Hospital, Pusan (Korea, Republic of)

    1994-05-15

    To evaluate the significance of high signal intensity of the septum pellucidum in hydrocephalus on proton density-weighted brain MR images. Authors reviewed the MR images of 418 cases of patients with normal (175 case), hydrocephalic(35 cases), atrophic(58 cases), and other groups(150 cases) retrospectively. We analyzed the signal intensity of the septum pellucidum in the normal group and the incidences of high signal intensities of periventricular area of frontal horn of lateral ventricle(area 1), periventricular area except area 1 (area 2), callososeptal area(area 3), and septum pellucidum(area 4) in the normal and abnormal groups. In the normal group, the septum pellucidum was isointense to the head of caudate nucleus on proton density-weighted image. High signal intensity of the septum pellucidum was seen in 31 cases (22 cases of hydrocephalus, 5 cases of brain atrophy, and 4 cases of others), and showed high specificity(91.4%) for hydrocephalus in spite of low sensitivity(62.9%), as compared with periventricular hyperintensities of other areas. High signal intensity of the septum pellucidum on proton density- weighted image may be caused by transependymal CSF migration in the patients with hydrocephalus, and considered as an additional finding of hydrocephalus in the cases of ventriculomegaly.

  2. HYSTEROSCOPIC RESECTION OF UTERINE SEPTUM – EFFECTS ON PREGNANCY

    Directory of Open Access Journals (Sweden)

    Helena Ban

    2003-12-01

    Full Text Available Background. In women with spontaneous abortions, preterm deliveries or infertility, septate uterus is often detected on transvaginal ultrasound examination. Since 1993 we have used hysteroscopic resection to correct this anomaly. The aim of this study was to evaluate the effect of the arcuate uterus on the course of pregnancy and its outcome, and the effect of hysteroscopic resection of the arcuate uterus on the prognosis of pregnancy.Patients and methods. Retrospectively we analyzed prospectively collected data. Between 15 February 1993 and 31 December 1999 we performed 760 hysteroscopic resections of the septum at the Department of Obstetrics and Gynecology in Ljubljana. We evaluated the course of pregnancy and its outcome only, therefore we enrolled 241 women, who conceived spontaneously before and after operation.Results. In the group of women with arcuate uterus (n = 111 there were 244 pregnancies before hysteroscopic resection: 38 (15.6% ended with a delivery and 202 (82.8% with a spontaneous abortion. In the group of women with septate uterus (n = 130 there were 269 pregnancies: 42 deliveries (15.6% and 224 (83.3% spontaneous abortions. After hysteroscopic resection there were 109 pregnancies in the women with arcuate uterus: 91 (83.5% deliveries and 16 (14.7% spontaneous abortions; in the septate uterus group there were 118 pregnancies: 98 (83.2% deliveries and 16 (13.5% spontaneous abortions. In both groups there was a significant improvement in the delivery rate (p < 0.00000. Before resection the preterm delivery rates were significantly higher in both groups (arcuate: 50.0%; septate: 35.1% than after the resection (arcuate: 11.3%; septate 17.7%.Conclusions. The women with either septate or arcuate uterus are at a higher risk for spontaneous abortion and preterm delivery. Hysteroscopic resection significantly decreases the risk in both groups of women.

  3. Diagonal queue medical image steganography with Rabin cryptosystem.

    Science.gov (United States)

    Jain, Mamta; Lenka, Saroj Kumar

    2016-03-01

    The main purpose of this work is to provide a novel and efficient method to the image steganography area of research in the field of biomedical, so that the security can be given to the very precious and confidential sensitive data of the patient and at the same time with the implication of the highly reliable algorithms will explode the high security to the precious brain information from the intruders. The patient information such as patient medical records with personal identification information of patients can be stored in both storage and transmission. This paper describes a novel methodology for hiding medical records like HIV reports, baby girl fetus, and patient's identity information inside their Brain disease medical image files viz. scan image or MRI image using the notion of obscurity with respect to a diagonal queue least significant bit substitution. Data structure queue plays a dynamic role in resource sharing between multiple communication parties and when secret medical data are transferred asynchronously (secret medical data not necessarily received at the same rate they were sent). Rabin cryptosystem is used for secret medical data writing, since it is computationally secure against a chosen-plaintext attack and shows the difficulty of integer factoring. The outcome of the cryptosystem is organized in various blocks and equally distributed sub-blocks. In steganography process, various Brain disease cover images are organized into various blocks of diagonal queues. The secret cipher blocks and sub-blocks are assigned dynamically to selected diagonal queues for embedding. The receiver gets four values of medical data plaintext corresponding to one ciphertext, so only authorized receiver can identify the correct medical data. Performance analysis was conducted using MSE, PSNR, maximum embedding capacity as well as by histogram analysis between various Brain disease stego and cover images.

  4. Reducing Memory Cost of Exact Diagonalization using Singular Value Decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Weinstein, Marvin; /SLAC; Auerbach, Assa; /Stanford U., Phys. Dept. /Technion; Chandra, V.Ravi; /Technion

    2011-11-04

    We present a modified Lanczos algorithm to diagonalize lattice Hamiltonians with dramatically reduced memory requirements. The lattice of size N is partitioned into two subclusters. At each iteration the Lanczos vector is projected into a set of n{sub svd} smaller subcluster vectors using singular value decomposition. For low entanglement entropy S{sub ee}, (satisfied by short range Hamiltonians), we expect the truncation error to vanish as exp(-n{sup 1/S{sub ee}}{sub svd}). Convergence is tested for the Heisenberg model on Kagome clusters of up to 36 sites, with no symmetries exploited, using less than 15GB of memory. Generalization to multiple partitioning is discussed.

  5. Exact diagonalization: the Bose-Hubbard model as an example

    Science.gov (United States)

    Zhang, J. M.; Dong, R. X.

    2010-05-01

    We take the Bose-Hubbard model to illustrate exact diagonalization techniques in a pedagogical way. We follow the route of first generating all the basis vectors, then setting up the Hamiltonian matrix with respect to this basis and finally using the Lanczos algorithm to solve low lying eigenstates and eigenvalues. Emphasis is placed on how to enumerate all the basis vectors and how to use the hashing trick to set up the Hamiltonian matrix or matrices corresponding to other quantities. Although our route is not necessarily the most efficient one in practice, the techniques and ideas introduced are quite general and may find use in many other problems.

  6. Performance Theory of Diagonal Conducting Wall MHD Accelerators

    Science.gov (United States)

    Litchford, R. J.

    2003-01-01

    The theoretical performance of diagonal conducting wall crossed field accelerators is examined on the basis of an infinite segmentation assumption using a cross-plane averaged generalized Ohm's law for a partially ionized gas, including ion slip. The desired accelerator performance relationships are derived from the cross-plane averaged Ohm's law by imposing appropriate configuration and loading constraints. A current dependent effective voltage drop model is also incorporated to account for cold-wall boundary layer effects including gasdynamic variations, discharge constriction, and electrode falls. Definition of dimensionless electric fields and current densities lead to the construction of graphical performance diagrams, which further illuminate the rudimentary behavior of crossed field accelerator operation.

  7. Experimental Investigation of Stator Flow in Diagonal Flow Fan

    Institute of Scientific and Technical Information of China (English)

    Jie Wang; Yoichi Kinoue; Norimasa Shiomi; Toshiaki Setoguchi; Kenji Kaneko; Yingzi Jin

    2008-01-01

    perimental investigations were conducted for the internal flow of the stator of the diagonal flow fan. Comer separation near the hub surface and the suction surface of the stator blade are focused on. At the design flow rate, the values of the axial velocity and the total pressure at stator outlet decrease near the suction surface at around the hub surface by the influence of the comer wall. At low flow rate of 80-90 % of the design flow rate, the comer separation between the suction surface and the hub surface can be found, which become widely spread at 80 % of the design flow rate.

  8. Experimental investigation of stator flow in diagonal flow fan

    Science.gov (United States)

    Wang, Jie; Kinoue, Yoichi; Shiomi, Norimasa; Setoguchi, Toshiaki; Kaneko, Kenji; Jin, Yingzi

    2008-12-01

    Experimental investigations were conducted for the internal flow of the stator of the diagonal flow fan. Corner separation near the hub surface and the suction surface of the stator blade are focused on. At the design flow rate, the values of the axial velocity and the total pressure at stator outlet decrease near the suction surface at around the hub surface by the influence of the corner wall. At low flow rate of 80-90 % of the design flow rate, the corner separation between the suction surface and the hub surface can be found, which become widely spread at 80 % of the design flow rate.

  9. Thermodynamics of Rh nuclear spins calculated by exact diagonalization

    DEFF Research Database (Denmark)

    Lefmann, K.; Ipsen, J.; Rasmussen, F.B.

    2000-01-01

    We have employed the method of exact diagonalization to obtain the full-energy spectrum of a cluster of 16 Rh nuclear spins, having dipolar and RK interactions between first and second nearest neighbours only. We have used this to calculate the nuclear spin entropy, and our results at both positive...... and negative temperatures follow the second-order high-temperature series expansions for \\T\\ > 3 nK. Our findings do not agree with the measurements of the former Rh experiment in Helsinki, where a deviation is seen at much higher temperatures. (C) 2000 Elsevier Science B.V. All rights reserved....

  10. Diagonal Cracking and Shear Strength of Reinforced Concrete Beams

    DEFF Research Database (Denmark)

    Zhang, Jin-Ping

    1997-01-01

    found by the usual plastic theory, a physical explanation is given for this phenomenon and a way to estimate the shear capacity of reinforced concrete beams, based on the theory of plasticity, is described. The theoretical calculations are shown to be in fairly good agreement with test results from......The shear failure of non-shear-reinforced concrete beams with normal shear span ratios is observed to be governed in general by the formation of a critical diagonal crack. Under the hypothesis that the cracking of concrete introduces potential yield lines which may be more dangerous than the ones...

  11. Injerto libre braquial medial Free medial arm graft

    OpenAIRE

    2007-01-01

    Introducción. Entre las reconstrucciones de defectos titulares de cabeza y cuello, el injerto libre microvascularizado braquial medial no ha adquirido mucha popularidad debido a las variaciones anatómicas que se reflejan en la vascularización de éste. Nuestro objetivo es realizar una descripción de la anatomía y técnica quirúrgica, así como una revisión de la literatura describiendo las ventajas y desventajas de este tipo de injerto. Material y método. Presentamos el caso de una paciente con ...

  12. On the performance of diagonal lattice space-time codes

    KAUST Repository

    Abediseid, Walid

    2013-11-01

    There has been tremendous work done on designing space-time codes for the quasi-static multiple-input multiple output (MIMO) channel. All the coding design up-to-date focuses on either high-performance, high rates, low complexity encoding and decoding, or targeting a combination of these criteria [1]-[9]. In this paper, we analyze in details the performance limits of diagonal lattice space-time codes under lattice decoding. We present both lower and upper bounds on the average decoding error probability. We first derive a new closed-form expression for the lower bound using the so-called sphere lower bound. This bound presents the ultimate performance limit a diagonal lattice space-time code can achieve at any signal-to-noise ratio (SNR). The upper bound is then derived using the union-bound which demonstrates how the average error probability can be minimized by maximizing the minimum product distance of the code. Combining both the lower and the upper bounds on the average error probability yields a simple upper bound on the the minimum product distance that any (complex) lattice code can achieve. At high-SNR regime, we discuss the outage performance of such codes and provide the achievable diversity-multiplexing tradeoff under lattice decoding. © 2013 IEEE.

  13. Alcohol dimers--how much diagonal OH anharmonicity?

    Science.gov (United States)

    Kollipost, Franz; Papendorf, Kim; Lee, Yu-Fang; Lee, Yuan-Pern; Suhm, Martin A

    2014-08-14

    The OH bond of methanol, ethanol and t-butyl alcohol becomes more anharmonic upon hydrogen bonding and the infrared intensity ratio between the overtone and the fundamental transition of the bridging OH stretching mode decreases drastically. FTIR spectroscopy of supersonic slit jet expansions allows to quantify these effects for isolated alcohol dimers, enabling a direct comparison to anharmonic vibrational predictions. The diagonal anharmonicity increase amounts to 15-18%, growing with increasing alkyl substitution. The overtone/fundamental IR intensity ratio, which is on the order of 0.1 or more for isolated alcohols, drops to 0.004-0.001 in the hydrogen-bonded OH group, making overtone detection very challenging. Again, alkyl substitution enhances the intensity suppression. Vibrational second order perturbation theory appears to capture these effects in a semiquantitative way. Harmonic quantum chemistry predictions for the hydrogen bond-induced OH stretching frequency shift (the widely used infrared signature of hydrogen bonding) are insufficient, and diagonal anharmonicity corrections from experiment make the agreement between theory and experiment worse. Inclusion of anharmonic cross terms between hydrogen bond modes and the OH stretching mode is thus essential, as is a high level electronic structure theory. The isolated molecule results are compared to matrix isolation data, complementing earlier studies in N2 and Ar by the more weakly interacting Ne and p-H2 matrices. Matrix effects on the hydrogen bond donor vibration are quantified.

  14. The "diagonal effect": a systematic error in oblique antisaccades.

    Science.gov (United States)

    Koehn, John D; Roy, Elizabeth; Barton, Jason J S

    2008-08-01

    Antisaccades are known to show greater variable error and also a systematic hypometria in their amplitude compared with visually guided prosaccades. In this study, we examined whether their accuracy in direction (as opposed to amplitude) also showed a systematic error. We had human subjects perform prosaccades and antisaccades to goals located at a variety of polar angles. In the first experiment, subjects made prosaccades or antisaccades to one of eight equidistant locations in each block, whereas in the second, they made saccades to one of two equidistant locations per block. In the third, they made antisaccades to one of two locations at different distances but with the same polar angle in each block. Regardless of block design, the results consistently showed a saccadic systematic error, in that oblique antisaccades (but not prosaccades) requiring unequal vertical and horizontal vector components were deviated toward the 45 degrees diagonal meridians. This finding could not be attributed to range effects in either Cartesian or polar coordinates. A perceptual origin of the diagonal effect is suggested by similar systematic errors in other studies of memory-guided manual reaching or perceptual estimation of direction, and may indicate a common spatial bias when there is uncertain information about spatial location.

  15. Acute Medial Plantar Fascia Tear.

    Science.gov (United States)

    Pascoe, Stephanie C; Mazzola, Timothy J

    2016-06-01

    A 32-year-old man who participated in competitive soccer came to physical therapy via direct access for a chief complaint of plantar foot pain. The clinical examination findings and mechanism of injury raised a concern for a plantar fascia tear, so the patient was referred to the physician and magnetic resonance imaging was obtained. The magnetic resonance image confirmed a high-grade, partial-thickness, proximal plantar fascia tear with localized edema at the location of the medial band. J Orthop Sports Phys Ther 2016;46(6):495. doi:10.2519/jospt.2016.0409.

  16. Case of absence of the septum pellucidum accompanied with hydrocephalus and detected by computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Tominaga, K.; Kobayashi, E.; Yamamoto, K.; Asakura, T. (Kagoshima Univ. (Japan). Faculty of Medicine)

    1981-06-01

    A case of absence of the septum pellucidum accompanied with hydrocephalus in a 56 year old woman who had complained headache, dizziness and numbness of left leg was reported. Absence of the septum pellucidum in this case had not been detected until CT scan was performed. Ventriculoperitoneal shunt was performed, then her complaints were cleared up. The discussion was limited as far as possible to absence of the septum pellucidum without agenesis of the corpus callosum with a few references. Encephalographic characteristics of absence of the septum pellucidum were first noted by Foster in 1935. The real prevalence should lie at about 1 : 400 in a sufficiently large encephalographical series, which should be an estimate between 2 and 3 per 100,000 of population. Encephalography, although, afflicts patients with headache, nausea and vomiting, moreover it accompanied with possible intracranial infection. On the other hand, CT scan has cleared up these problems, we can perform it easily in many cases, and know about status of the septum pellucidum. Further examination for more distinct information are taken by coronal section and ''high definition 5 mm slice thickness'' of CT scan.

  17. Natural Diagonal Riemannian Almost Product and Para-Hermitian Cotangent Bundles

    CERN Document Server

    Druta-Romaniuc, Simona-Luiza

    2011-01-01

    We obtain the natural diagonal almost product and locally product structures on the total space of the cotangent bundle of a Riemannian manifold. We find the Riemannian almost product (locally product) and the (almost) para-Hermitian cotangent bundles of natural diagonal lift type. We prove the characterization theorem for the natural diagonal (almost) para-K\\"ahlerian structures on the total spaces of the cotangent bundle.

  18. Small polaron with generic open boundary conditions: Exact solution via the off-diagonal Bethe ansatz

    Directory of Open Access Journals (Sweden)

    Xiaotian Xu

    2015-09-01

    Full Text Available The small polaron, a one-dimensional lattice model of interacting spinless fermions, with generic non-diagonal boundary terms is studied by the off-diagonal Bethe ansatz method. The presence of the Grassmann valued non-diagonal boundary fields gives rise to a typical U(1-symmetry-broken fermionic model. The exact spectra of the Hamiltonian and the associated Bethe ansatz equations are derived by constructing an inhomogeneous T–Q relation.

  19. Diagonal complexes and the integral homology of the automorphism group of a free product

    CERN Document Server

    Griffin, James

    2010-01-01

    We calculate the integral (co)homology of the group of symmetric automorphisms of a free product. We proceed by constructing a moduli space of cactus products and to describe this space a theory of diagonal complexes is introduced. In doing so we offer a generalisation of the theory of right-angled Artin groups in that each diagonal complex defines what we call a diagonal right-angled Artin group (DRAAG).

  20. Variant position of the medial plantar nerve

    OpenAIRE

    Astik RB; Dave UH; Gajendra KS

    2011-01-01

    Knowledge of variation of position of the medial plantar nerve is important for the forefoot surgeon for plantar reconstruction, local injection therapy and an excision of interdigital neuroma. During routine dissection of 50-year-old female cadaver, we found the medial plantar nerve and vessels variably located between plantar aponeurosis and the muscles of the first layer of the sole of the right foot. Due to this variant position, the medial plantar nerve and vessels lose their protection ...

  1. The dragonfly splint: a new disposable device designed to prevent both medial and lateral turbinate synechiae after sinonasal surgery.

    Science.gov (United States)

    Mantovani, Mario; Rinaldi, Vittorio; Torretta, Sara; Sigismund, Paolo Enrico; Cappadona, Maurizio; Minetti, Andrea; Pignataro, Lorenzo

    2014-03-01

    Periturbinal adhesions are among the most frequent and challenging complications of sinonasal surgery. Endonasal paraseptal splints have proved to be very efficient in preventing "medial synechiae," that is, adhesions located between the medial faces of the middle/inferior turbinates and the septum. However, none of these devices for guiding mucosal healing can prevent "lateral synechiae" (adhesions between the lateral face of the middle turbinate and the lateral nasal wall) inside the middle meatal cleft, which is a very critical area for the physiology of the anterior sinus system. For this reason, if followed by the formation of lateral synechiae, the surgical maneuvers used to treat sinus diseases could paradoxically become a cause of persistent functional impairment and lead to iatrogenic sinusitis or mucocele.We describe our preliminary experience with a new endonasal splint called "Dragonfly" (because of its shape), which has been designed to prevent both medial and lateral postsurgical synechiae. This device has a long lateral wing designed to separate the mucosal surfaces of the middle meatal/ethmoid cavities and prevent adhesions during the postoperative process of healing. The device must be kept in situ for 3 to 4 weeks to permit the re-epithelialization of the internal nasal surfaces. Our experience shows that the splints are well tolerated and highly efficient, preventing both medial and lateral synechiae in 100% of cases. A randomized controlled study has now been started to confirm these positive preliminary findings in a larger patient population.

  2. TRANSVERSE VAGINAL SEPTUM: A CONGENITAL MALFORMATION AND ITS MANAGEMENT IN A FEMALE DROMEDARY CAMEL

    Directory of Open Access Journals (Sweden)

    Z. I. Qureshi, M. Iqbal, A. Wahab, R. Yass and M. Naif

    2005-01-01

    Full Text Available A seven year old female dromedary camel was examined for the complaint of inability to breed due to problem during penile intromission. Vaginoscopy, using equine tube vaginoscope, revealed the presence of a tissue flap cranial to the urethral opening, buldging caudally and separating the cranial and caudal parts of vagina. Digital palpation was also performed and the condition was diagnosed as transverse vaginal septum. For treatment, the vaginal septum was grasped with an Allis tissue forceps and a circular piece was severed from the center with the Metzenbaum scissors. The remaining portion of septum was then carefully trimmed. About 28 days after surgery, the animal showed heat signs and was mated. On ultrasonographic examination three months, post mating the animal was found pregnant.

  3. Horizontal ventricular septum with dextroversion: hearts with and without aortic atresia.

    Science.gov (United States)

    Thilenius, O G; Bharati, S; Lev, M; Karp, R B; Arcilla, R A

    1987-01-01

    Two hearts with horizontal ventricular septum, dextroversion (situs solitus), ventricular septal defects, and malaligned great vessels are reported. One of the hearts had aortic atresia and the infant died; the other patient had a Fontan-type physiologic correction. Reviewing the literature, the following conclusions are drawn: (a) Hearts with horizontal ventricular septum and those with criss-cross atrioventricular connections may be the result of different degrees of rotation of the ventricular muscle mass. This rotation is not likely to be postseptational but preseptational. (b) Only those hearts with a complete 180 degrees rotation should be called criss-cross hearts. (c) Partial rotation results in a horizontal septum such that the right ventricle is invariably superior, regardless of atrioventricular concordance or discordance, situs solitus or inversus, or dextroversion. (d) Physiologic surgical correction is often possible but has to be tailored to the details of each heart.

  4. Upflow bioreactor having a septum and an auger and drive assembly

    Science.gov (United States)

    Hansen, Carl S.; Hansen, Conly L.

    2007-11-06

    An upflow bioreactor includes a vessel having an inlet and an outlet configured for upflow operation. A septum is positioned within the vessel and defines a lower chamber and an upper chamber. The septum includes an aperture that provides fluid communication between the upper chamber and lower chamber. The bioreactor also includes an auger positioned in the aperture of the septum. The vessel includes an opening in the top for receiving the auger. The auger extends from a drive housing, which is position over the opening and provides a seal around the opening. The drive housing is adjustable relative to the vessel. The position of the auger in the aperture can be adjusted by adjusting the drive housing relative to the vessel. The auger adjustment mechanism allows the auger to be accurately positioned within the aperture. The drive housing can also include a fluid to provide an additional seal around the shaft of the auger.

  5. Snapping Knee Caused by Medial Meniscal Cyst

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Ohishi

    2014-01-01

    Full Text Available Snapping phenomenon around the medial aspect of the knee is rare. We present this case of snapping knee caused by the sartorius muscle over a large medial meniscal cyst in a 66-year-old female. Magnetic resonance images demonstrated a large medial meniscal cyst with a horizontal tear of the medial meniscus. Arthroscopic cyst decompression with limited meniscectomy resulted in the disappearance of snapping, and no recurrence of the cyst was observed during a 2-year follow-up period.

  6. The R and D of half-sine pulser for eddy-current septum magnet

    CERN Document Server

    Fu Lu Xin; Kang Wen

    2002-01-01

    The SSRF requires high-amplitude half-sine pulse current (10kA) and relatively narrow pulse width (approx 60 mu s) for its eddy-current septum magnets. Moreover the machine will need a very high level of performance from the pulsers, particularly in terms of pulse amplitude stability and regulating range. For the convenience of maintenance the pulsers will be installed in the power supply hall and cabled to their eddy-current septum magnets by RG220/U. The author presents the pulser design and R and D results

  7. [One case of papillary adenocarcinoma located in the back-end of nasal septum].

    Science.gov (United States)

    Zang, Jian; Liu, Qian; Jiang, Xuejun

    2015-02-01

    Patients with nasopharyngeal foreign body sensation for 3 years, and had nasal obstruction in the past six months. electric nasopharyngoscopy: a irregular ellipse shape mass occupied in the nasopharynx, the mass surface is not smooth, with erosion ulcer and filthy secretions, the mass had a root in the back-end of nasal septum, and was adjacent to the bilateral round pillow. Sinus CT showed an irregular soft tissue shadow connected to the nasal septum backend in the nasopharynx, the size is about 2.8 cm X 3.5 cm, CT value is about 43 HU. Pathological examination: papillary adenocarcinoma.

  8. Surgically assisted rapid maxillary expansion (SARME) with or without intraoperative releasing of the nasal septum

    DEFF Research Database (Denmark)

    Jensen, Thomas; Rodrigo-Domingo, Maria

    2017-01-01

    computed tomography images from T1 to T3. Moreover, visible nasal septum deviation was assessed by using superimposed clinical photos obtained preoperatively (CP1) and before second-stage surgery (CP2). RESULTS: No significant differences were found between releasing and nonreleasing of the nasal septum...... in angular radiographic measurements from T1 to T3 (0 degrees; 95% confidence interval -0.62 to 0.62; P = .5) or visible nasal deviation from CP1 to CP2 (-0.14 degrees; 95% confidence interval -0.64 to 0.36; P = .28). CONCLUSIONS: The results of the present study indicate that there is no need...

  9. The Diagonal Compression Field Method using Circular Fans

    DEFF Research Database (Denmark)

    Hansen, Thomas

    2006-01-01

    In a concrete beam with transverse stirrups the shear forces are carried by inclined compression in the concrete. Along the tensile zone and the compression zone of the beam the transverse components of the inclined compressions are transferred to the stirrups, which are thus subjected to tension....... Since the eighties the diagonal compression field method has been used to design transverse shear reinforcement in concrete beams. The method is based on the lower-bound theorem of the theory of plasticity, and it has been adopted in Eurocode 2. The paper presents a new design method, which...... with low shear stresses. The larger inclination (the smaller -value) of the uniaxial concrete stress the more transverse shear reinforcement is needed; hence it would be optimal if the -value for a given beam could be set to a low value in regions with high shear stresses and thereafter increased...

  10. Cold bosons in optical lattices: a tutorial for exact diagonalization

    Science.gov (United States)

    Raventós, David; Graß, Tobias; Lewenstein, Maciej; Juliá-Díaz, Bruno

    2017-06-01

    Exact diagonalization (ED) techniques are a powerful method for studying many-body problems. Here, we apply this method to systems of few bosons in an optical lattice, and use it to demonstrate the emergence of interesting quantum phenomena such as fragmentation and coherence. Starting with a standard Bose-Hubbard Hamiltonian, we first revise the characterisation of the superfluid to Mott insulator (MI) transitions. We then consider an inhomogeneous lattice, where one potential minimum is made much deeper than the others. The MI phase due to repulsive on-site interactions then competes with the trapping of all atoms in the deep potential. Finally, we turn our attention to attractively interacting systems, and discuss the appearance of strongly correlated phases and the onset of localisation for a slightly biased lattice. The article is intended to serve as a tutorial for ED of Bose-Hubbard models.

  11. Non-Diagonal and Mixed Squark Production at Hadron Colliders

    CERN Document Server

    Bozzi, G; Klasen, M

    2005-01-01

    We calculate squared helicity amplitudes for non-diagonal and mixed squark pair production at hadron colliders, taking into account not only loop-induced QCD diagrams, but also previously unconsidered electroweak channels, which turn out to be dominant. Mixing effects are included for both top and bottom squarks. Numerical results are presented for several SUSY benchmark scenarios at both the CERN LHC and the Fermilab Tevatron, including the possibilities of light stops or sbottoms. The latter should be easily observed at the Tevatron in associated production of stops and sbottoms for a large range of stop masses and almost independently of the stop mixing angle. Asymmetry measurements for light stops at the polarized BNL RHIC collider are also briefly discussed.

  12. Exact Diagonalization of Heisenberg SU(N) models.

    Science.gov (United States)

    Nataf, Pierre; Mila, Frédéric

    2014-09-19

    Building on advanced results on permutations, we show that it is possible to construct, for each irreducible representation of SU(N), an orthonormal basis labeled by the set of standard Young tableaux in which the matrix of the Heisenberg SU(N) model (the quantum permutation of N-color objects) takes an explicit and extremely simple form. Since the relative dimension of the full Hilbert space to that of the singlet space on n sites increases very fast with N, this formulation allows us to extend exact diagonalizations of finite clusters to much larger values of N than accessible so far. Using this method, we show that, on the square lattice, there is long-range color order for SU(5), spontaneous dimerization for SU(8), and evidence in favor of a quantum liquid for SU(10).

  13. Eye movements during mental time travel follow a diagonal line.

    Science.gov (United States)

    Hartmann, Matthias; Martarelli, Corinna S; Mast, Fred W; Stocker, Kurt

    2014-11-01

    Recent research showed that past events are associated with the back and left side, whereas future events are associated with the front and right side of space. These spatial-temporal associations have an impact on our sensorimotor system: thinking about one's past and future leads to subtle body sways in the sagittal dimension of space (Miles, Nind, & Macrae, 2010). In this study we investigated whether mental time travel leads to sensorimotor correlates in the horizontal dimension of space. Participants were asked to mentally displace themselves into the past or future while measuring their spontaneous eye movements on a blank screen. Eye gaze was directed more rightward and upward when thinking about the future than when thinking about the past. Our results provide further insight into the spatial nature of temporal thoughts, and show that not only body, but also eye movements follow a (diagonal) "time line" during mental time travel.

  14. Performance Theory of Diagonal Conducting Wall Magnetohydrodynamic Accelerators

    Science.gov (United States)

    Litchford, R. J.

    2004-01-01

    The theoretical performance of diagonal conducting wall crossed-field accelerators is examined on the basis of an infinite segmentation assumption using a cross-plane averaged generalized Ohm s law for a partially ionized gas, including ion slip. The desired accelerator performance relationships are derived from the cross-plane averaged Ohm s law by imposing appropriate configuration and loading constraints. A current-dependent effective voltage drop model is also incorporated to account for cold-wall boundary layer effects, including gasdynamic variations, discharge constriction, and electrode falls. Definition of dimensionless electric fields and current densities leads to the construction of graphical performance diagrams, which further illuminate the rudimentary behavior of crossed-field accelerator operation.

  15. Quantum transport in chains with noisy off-diagonal couplings.

    Science.gov (United States)

    Pereverzev, Andrey; Bittner, Eric R

    2005-12-22

    We present a model for conductivity and energy diffusion in a linear chain described by a quadratic Hamiltonian with Gaussian noise. We show that when the correlation matrix is diagonal, the noise-averaged Liouville-von Neumann equation governing the time evolution of the system reduces to the [Lindblad, Commun. Math. Phys. 48, 119 (1976)] equation with Hermitian Lindblad operators. We show that the noise-averaged density matrix for the system expectation values of the energy density and the number density satisfies discrete versions of the heat and diffusion equations. Transport coefficients are given in terms of model Hamiltonian parameters. We discuss conditions on the Hamiltonian under which the noise-averaged expectation value of the total energy remains constant. For chains placed between two heat reservoirs, the gradient of the energy density along the chain is linear.

  16. An Off Diagonal Marcinkiewicz Interpolation Theorem on Lorentz Spaces

    Institute of Scientific and Technical Information of China (English)

    Yi Yu LIANG; Li Guang LIU; Da Chun YANG

    2011-01-01

    Let(X,μ)be a measure space.In this paper,using some ideas from Grafakos and Kalton,the authors establish an of diagonal Marcinkiewicz interpolation theorem for a quasilinear operator T in Lorentz spaces Lp,q(X)with p,q∈(0,∞],which is a corrected version of Theorem 1.4.19 in[Grafakos,L.:Classical Fourier Analysis,Second Edition,Graduate Texts in Math.,No.249,Springer,New York,2008]and which,in the case that T is linear or nonnegative sublineaa,P∈[1,∞)and q∈[1,∞),was obtained by Stein and Weiss [Introduction to Fourier Analysis on Euclidean Spaces,Princeton University Press,Princeton,N.J.,1971].

  17. Efficient numerical diagonalization of hermitian 3x3 matrices

    CERN Document Server

    Kopp, J

    2006-01-01

    A very common problem in science is the numerical diagonalization of symmetric or hermitian 3x3 matrices. Since standard "black box" packages may be very inefficient if the number of matrices is large, we study several alternatives. We consider optimized implementations of the Jacobi, QL, and Cuppen algorithms and compare them with a new, carefully designed analytical method relying on Cardano's formula for the eigenvalues and on vector cross products for the eigenvectors. This analytical algorithm outperforms the other algorithms by more than a factor of 2, but may be less accurate if the eigenvalues differ greatly in magnitude. Jacobi is the most accurate, but also the slowest method, while QL and Cuppen are good general purpose algorithms. For all algorithms, we give an overview of the underlying mathematical ideas, and present detailed benchmark results. C and Fortran implementations of our code are available for download from http://www.mpi-hd.mpg.de/~jkopp/3x3/ .

  18. Diagonalization of the XXZ Hamiltonian by Vertex Operators

    CERN Document Server

    Davies, B; Jimbo, M; Miwa, T; Nakayashiki, A; Davies, Brian; Foda, Omar; Jimbo, Michio; Miwa, Tetsuji; Nakayashiki, Atsushi

    1993-01-01

    We diagonalize the anti-ferroelectric XXZ-Hamiltonian directly in the thermodynamic limit, where the model becomes invariant under the action of affine U_q( sl(2) ). Our method is based on the representation theory of quantum affine algebras, the related vertex operators and KZ equation, and thereby bypasses the usual process of starting from a finite lattice, taking the thermodynamic limit and filling the Dirac sea. From recent results on the algebraic structure of the corner transfer matrix of the model, we obtain the vacuum vector of the Hamiltonian. The rest of the eigenvectors are obtained by applying the vertex operators, which act as particle creation operators in the space of eigenvectors. We check the agreement of our results with those obtained using the Bethe Ansatz in a number of cases, and with others obtained in the scaling limit --- the $su(2)$-invariant Thirring model.

  19. Performance Study of Diagonally Segmented Piezoelectric Vibration Energy Harvester

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Eun [Catholic Univ. of Daegu, Daegu (Korea, Republic of)

    2013-08-15

    This study proposes a piezoelectric vibration energy harvester composed of two diagonally segmented energy harvesting units. An auxiliary structural unit is attached to the tip of a host structural unit cantilevered to a vibrating base, where the two components have beam axes in opposite directions from each other and matched short-circuit resonant frequencies. Contrary to the usual observations in two resonant frequency-matched structures, the proposed structure shows little eigenfrequency separation and yields a mode sequence change between the first two modes. These lead to maximum power generation around a specific frequency. By using commercial finite element software, it is shown that the magnitude of the output power from the proposed vibration energy harvester can be substantially improved in comparison with those from conventional cantilevered energy harvesters with the same footprint area and magnitude of a tip mass.

  20. Progressive Perforation of the Nasal Septum Due to Leishmania major: A Case of Mucosal Leishmaniasis in a Traveler.

    Science.gov (United States)

    Harrison, Nicole; Walochnik, Julia; Ramsebner, Reinhard; Veletzky, Luzia; Lagler, Heimo; Ramharter, Michael

    2017-03-01

    AbstractThis report describes a case of mucosal leishmaniasis caused by Leishmania major with destructive perforation of the nasal septum illustrating the diagnostic challenges of a rare clinical presentation of L. major infection in a traveler. The atypical presentation may have been associated with the use of cortisone as a potential trigger for the progressive destruction of the nasal septum.

  1. On the diagonal susceptibility of the two-dimensional Ising model

    Energy Technology Data Exchange (ETDEWEB)

    Tracy, Craig A. [Department of Mathematics, University of California, Davis, California 95616 (United States); Widom, Harold [Department of Mathematics, University of California, Santa Cruz, California 95064 (United States)

    2013-12-15

    We consider the diagonal susceptibility of the isotropic 2D Ising model for temperatures below the critical temperature. For a parameter k related to temperature and the interaction constant, we extend the diagonal susceptibility to complex k inside the unit disc, and prove the conjecture that the unit circle is a natural boundary.

  2. Off-diagonal Bethe ansatz solution of the XXX spin chain with arbitrary boundary conditions

    Science.gov (United States)

    Cao, Junpeng; Yang, Wen-Li; Shi, Kangjie; Wang, Yupeng

    2013-10-01

    Employing the off-diagonal Bethe ansatz method proposed recently by the present authors, we exactly diagonalize the XXX spin chain with arbitrary boundary fields. By constructing a functional relation between the eigenvalues of the transfer matrix and the quantum determinant, the associated T-Q relation and the Bethe ansatz equations are derived.

  3. Off-diagonal Bethe ansatz solution of the XXX spin-chain with arbitrary boundary conditions

    CERN Document Server

    Cao, Junpeng; Shi, Kangjie; Wang, Yupeng

    2013-01-01

    With the off-diagonal Bethe ansatz method proposed recently by the present authors, we exactly diagonalize the $XXX$ spin chain with arbitrary boundary fields. By constructing a functional relation between the eigenvalues of the transfer matrix and the quantum determinant, the associated $T-Q$ relation and the Bethe ansatz equations are derived.

  4. Algebraic Bethe Ansatz for O(2N) sigma models with integrable diagonal boundaries

    CERN Document Server

    Gombor, Tamas

    2015-01-01

    The finite volume problem of O(2N) sigma models with integrable diagonal boundaries on a finite interval is investigated. The double row transfer matrix is diagonalized by Algebraic Bethe Ansatz. The boundary Bethe Yang equations for the particle rapidities and the accompanying Bethe Ansatz equations are derived.

  5. Diagonally implicit Runge-Kutta methods for 3D shallow water applications

    NARCIS (Netherlands)

    P.J. van der Houwen; B.P. Sommeijer (Ben)

    1999-01-01

    textabstractWe construct A-stable and L-stable diagonally implicit Runge-Kutta methods of which the diagonal vector in the Butcher matrix has a minimal maximum norm. If the implicit Runge-Kutta relations are iteratively solved by means of the approximately factorized Newton process, then such

  6. Algebraic Bethe Ansatz for O(2N) sigma models with integrable diagonal boundaries

    Energy Technology Data Exchange (ETDEWEB)

    Gombor, Tamás [MTA Lendület Holographic QFT Group, Wigner Research Centre,H-1525 Budapest 114, P.O.B. 49 (Hungary); Institute for Theoretical Physics, Roland Eötvös University,1117 Budapest, Pázmány s. 1/A (Hungary); Palla, László [Institute for Theoretical Physics, Roland Eötvös University,1117 Budapest, Pázmány s. 1/A (Hungary)

    2016-02-24

    The finite volume problem of O(2N) sigma models with integrable diagonal boundaries on a finite interval is investigated. The double row transfer matrix is diagonalized by Algebraic Bethe Ansatz. The boundary Bethe Yang equations for the particle rapidities and the accompanying Bethe Ansatz equations are derived.

  7. Medial Patella Subluxation: Diagnosis and Treatment

    Science.gov (United States)

    McCarthy, Mark A.; Bollier, Mathew J.

    2015-01-01

    Medial patella subluxation is a disabling condition typically associated with previous patellofemoral instability surgery. Patients often describe achy pain with painful popping episodes. They often report that the patella shifts laterally, which occurs as the medial subluxed patella dramatically shifts into the trochlear groove during early knee flexion. Physical examination is diagnostic with a positive medial subluxation test. Nonoperative treatment, such as focused physical therapy and patellofemoral stabilizing brace, is often unsuccessful. Primary surgical options include lateral retinacular repair/imbrication or lateral reconstruction. Prevention is key to avoid medial patella subluxation. When considering patellofemoral surgery, important factors include appropriate lateral release indications, consideration of lateral retinacular lengthening vs release, correct MPFL graft placement and tension, and avoiding excessive medialization during tubercle transfer. This review article will analyze patient symptoms, diagnostic exam findings and appropriate treatment options, as well as pearls to avoid this painful clinical entity. PMID:26361441

  8. Differences in Visual-Spatial Input May Underlie Different Compression Properties of Firing Fields for Grid Cell Modules in Medial Entorhinal Cortex

    Science.gov (United States)

    2015-11-19

    noise. The legend in (A) applies to all panels (A-D). In (D) the blue (model) and black line (data) overlap. (E-F) Euclidean error computed from...10−4 Velocity controlled oscillator model Oscillation of theta rhythm f = 7.38 Hz Parameter for grid spacing–moving feature system β1 = 0.004...vector and by the parameter βl. The oscillation ω could be provided by the theta rhythm oscillations regulated by the medial septum [36]. In the model

  9. Automated intraventricular septum segmentation using non-local spatio-temporal priors.

    Science.gov (United States)

    Gupta, Mithun Das; Thiruvenkadam, Sheshadri; Subramanian, Navneeth; Govind, Satish

    2012-01-01

    Automated robust segmentation of intra-ventricular septum (IVS) from B-mode echocardiographic images is an enabler for early quantification of cardiac disease. Segmentation of septum from ultrasound images is very challenging due to variations in intensity/contrast in and around the septum, speckle noise and non-rigid shape variations of the septum boundary. In this work, we effectively address these challenges using an approach that merges novel computer vision ideas with physiological markers present in cardiac scans. Specifically, we contribute towards the following: (1) A novel 1-D active contour segmentation approach that utilizes non-local (NL) temporal cues, (2) Robust initialization of the active contour framework, based on NL-means de-noising, and MRF based clustering that incorporates physiological cues. We validate our claims using cardiac measurement results on approximately 30 cardiac scan videos (approximately 2000 ultrasound frames in total). Our method is fully automatic and near real time (0.1 sec/frame) implementation.

  10. Cavum septum pellucidum in a case of schizophrenia presenting with self-mutilating behavior.

    Science.gov (United States)

    Umesh, Shreekantiah; Bose, Swarnali; Khanra, Sourav; Das, Basudeb; Nizamie, S Haque

    2015-01-01

    Cavum septum pellucidum (CSP) is a neurodevelopmental anomaly, which is commonly reported in schizophrenia patients. Various symptoms of schizophrenia, including thought disturbances have been associated with CSP. We present a rare case of undifferentiated schizophrenia with CSP who presented with self-mutilating behaviors.

  11. Compact fluorescent lamp using horizontal and vertical insulating septums and convective venting geometry

    Science.gov (United States)

    Siminovitch, Michael

    1998-01-01

    A novel design for a compact fluorescent lamp, including a lamp geometry which will increase light output and efficacy of the lamp in a base down operating position by providing horizontal and vertical insulating septums positioned in the ballast compartment of the lamp to provide a cooler coldspot. Selective convective venting provides additional cooling of the ballast compartment.

  12. Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart

    NARCIS (Netherlands)

    D. Franco; S.M. Meilhac; V.M. Christoffels; A. Kispert; M. Buckingham; R.G. Kelly

    2006-01-01

    Mammalian heart development involves complex morphogenetic events which lead to the formation of fully separated left and right atrial and ventricular chambers from a tubular heart. Separation of left and right ventricular chambers is dependent on a single structure, the interventricular septum (IVS

  13. Ultrasonographic Evaluation of the Prevalence of an Intracompartmental Septum in Patients With de Quervain's Disease.

    Science.gov (United States)

    Sato, Junko; Ishii, Yoshinori; Noguchi, Hideo

    2016-01-01

    It has been reported that more patients with de Quervain's disease who had undergone surgical treatment had a septated dorsal compartment than did normal cadavers. The purpose of this study was to sonographically evaluate the prevalence of an intracompartmental septum in patients with de Quervain's disease and to compare the prevalence between groups categorized by sex, age, and peripartum status. The authors performed an ultrasonographic examination of 112 wrists from 103 patients with de Quervain's disease. The prevalence of a septum-like structure in the first compartment was compared between men and women, between older (≥40 years) and younger (≤39 years) patients, and between pregnant or lactating women and other patients. The prevalence of intracompartmental septum in patients with de Quervain's disease was 61.6% (69 of 112). Of the 69 wrists with an intracompartmental septum-like structure, 53 showed this structure completely through the level of the radial styloid, and 16 showed it partially on the level of the distal radial styloid. There was no significant difference between any 2 groups categorized by the patients' demographics. The prevalence of intracompartmental septation in the patients with de Quervain's disease was higher than the previously reported prevalence in cadavers and lower than that of patients who underwent surgery. This result was consistent with a previous report that patients with a septated dorsal compartment may be more at risk of contracting de Quervain's disease and more prone to failure of nonoperative treatment.

  14. A wide-band compact end-entry septum polariser OMT

    Science.gov (United States)

    Dang, N. D.; Kapartis, S.; Brain, D. J.

    The theoretical design and measured performance of an extremely compact wide-band end-entry septum polarizer orthomode transducer (OMT) are described. The in-line configuration is compatible with the requirements of a closely packed feed array geometry. It is noted that this OMT offers a significantly better performance than previously published empirical designs within a much shorter length.

  15. VOICE RELATED QUALITY OF LIFE IN INDIVIDUALS WITH DEVIATED NASAL SEPTUM

    Directory of Open Access Journals (Sweden)

    Prakash

    2014-08-01

    Full Text Available Deviated nasal septum (DNS is a common disorder which alters the nasal cavity anatomically and physiologically and results in nasal obstruction for breathing, nasal blockage, allergies, allergic rhinitis, and dryness of throat, thus influencing the person’s quality of life. Literature indicates that acoustic and resonatory characteristics of voice are negatively influenced in individuals with DNS due to the compensation by laryngeal system to the blockage in the resonatory chamber. In this context, the present study was aimed to investigate the voice related quality of life in individuals with deviated nasal septum. Forty individuals with severely deviated nasal septum confirmed by an Otorhinolaryngologist through anterior rhinoscopy, computerized tomography and twenty five age and gender matched controls filled the Kannada version of Voice Handicap Index-10 (VHI questionnaire. Results indicated significant impact of deviated nasal septum on voice related quality of life in 55% of the participants with DNS. Results of Mann-Whitney U test indicated significant effect of DNS on VHI scores in individuals with DNS compared to controls (p<0.001. With respect to response to the individual questions under VHI, although response was negative to most of the questions, two questions that received highest score belong to physical domain of VHI and are related to breathing difficulty and variations in voice throughout the day, indicating that they have more difficulty due to nasal blockage to airflow per se than their day-to-day functionality or communication.

  16. Deformation of the nasal septum in children, adolescents, and adults in Western Pomerania Province of Poland

    Directory of Open Access Journals (Sweden)

    Teul I

    2009-12-01

    Full Text Available Abstract Objectives Nasal septum deformation (NSD contributes to the occurrence of upper respiratory tract diseases in around 45-55% of Poland's population. The evaluation of frequency of occurrence and type of nasal septum deformation among randomly chosen representatives of the Szczecin and surrounding area population was the aim of this study. Methods NSD was assessed in 235 patients (123 male, 112 female aged 5-60. Mladina's classification system was used for the evaluation. Results Deformations of nasal septum were found in 43% of the examined subjects. Type 3 of NSD dominated (12.4%, while types 2 and 1 were found in 10.3% and 4.2% of the subjects, respectively. 9.2% of the patients showed type 5 of deformation, while types 6, 4, and 7 were found in 1.3%, 3.2% and 2.7% of the patients, respectively. Conclusions Straight nasal septum was found in females more often than in males, mostly on the left side. Associations between NSD, on one side, and age, sex, and traumas, on the other were found. NSD influenced the quality of respiration and frequency of upper respiratory tract diseases in the examined subjects.

  17. Fertility, pregnancy, and delivery after biventricular repair for pulmonary atresia with an intact ventricular septum.

    NARCIS (Netherlands)

    Drenthen, W.; Pieper, P.G.; Roos-Hesselink, J.W.; Zoon, N.; Voors, A.A.; Mulder, B.J.M.; Dijk, A.P.J. van; Vliegen, H.W.; Sollie, K.M.; Ebels, T.; Veldhuisen, D.J. van

    2006-01-01

    The objective of the present study to investigate fertility, pregnancy, and delivery in women with biventricular repair for pulmonary atresia with an intact ventricular septum (PAIVS). Using a nationwide registry (CONCOR), 37 patients with pulmonary atresia were identified, 6 of whom (aged 21 to 34

  18. Iterative algorithm for joint zero diagonalization with application in blind source separation.

    Science.gov (United States)

    Zhang, Wei-Tao; Lou, Shun-Tian

    2011-07-01

    A new iterative algorithm for the nonunitary joint zero diagonalization of a set of matrices is proposed for blind source separation applications. On one hand, since the zero diagonalizer of the proposed algorithm is constructed iteratively by successive multiplications of an invertible matrix, the singular solutions that occur in the existing nonunitary iterative algorithms are naturally avoided. On the other hand, compared to the algebraic method for joint zero diagonalization, the proposed algorithm requires fewer matrices to be zero diagonalized to yield even better performance. The extension of the algorithm to the complex and nonsquare mixing cases is also addressed. Numerical simulations on both synthetic data and blind source separation using time-frequency distributions illustrate the performance of the algorithm and provide a comparison to the leading joint zero diagonalization schemes.

  19. Three-Dimensional Evaluation of Implant Positioning in the Maxillary Sinus Septum: A Retrospective Study

    Science.gov (United States)

    Dragan, Eliza; Guillaume, Odri A.; Haba, Danisia; Olszewski, Raphael

    2015-01-01

    Background The aim of this study was to simulate implant placement in the maxillary sinus septum, as a potential alternative site to avoid sinus grafting. Material/Methods One hundred partially or completely edentulous patients, with their maxillary sinus septum present in the edentulous region, were selected from the database of the Department of Maxillofacial Surgery, Cliniques Universitaires Saint Luc, Bruxelles, Belgium. Three-dimensional (3D) reconstructions were created using 3D planning software. 3D reconstructions were performed for each maxillary sinus. Using the software implant library, the implants that presented the best fit with the maxillary sinus septum and that followed the established inclusion criteria were selected. Results All of the implants were inserted in premolar and molar regions. Most implants were inserted in the position of the second molar (21 of 55) or in the position of the first molar (17 of 55). In all sites the most frequently used implant was 4 mm in diameter and 7 mm in height. The mean coronal angle for the implant was 80.19±17.13 degrees and the mean sagittal angle was 94.83±9.94 degrees. The septal height represents 38.13% of the total available bone height (ABH). The mean percentage of the septum used to insert the implants was 47.33±2.47%. The septum increased the available bone height by a mean value of 2.18±1.47 mm. In 45 cases, the septa did not permit implant placement. Conclusions In completely edentulous patients, inserting implants in sinus septa does not exclude the need for sinus grafting, but in partially edentulous patients, this minimally invasive technique is an alternative to subantral augmentation. PMID:26363865

  20. [Improvement of child survival in Mexico: the diagonal approach].

    Science.gov (United States)

    Sepúlveda, Jaime; Bustreo, Flavia; Tapia, Roberto; Rivera, Juan; Lozano, Rafael; Olaiz, Gustavo; Partida, Virgilio; García-García, Ma de Lourdes; Valdespino, José Luis

    2007-01-01

    Public health interventions aimed at children in Mexico have placed the country among the seven countries on track to achieve the goal of child mortality reduction by 2015. We analysed census data, mortality registries, the nominal registry of children, national nutrition surveys, and explored temporal association and biological plausibility to explain the reduction of child, infant, and neonatal mortality rates. During the past 25 years, child mortality rates declined from 64 to 23 per 1000 livebirths. A dramatic decline in diarrhoea mortality rates was recorded. Polio, diphtheria, and measles were eliminated. Nutritional status of children improved significantly for wasting, stunting, and underweight. A selection of highly cost-effective interventions bridging clinics and homes, what we called the diagonal approach, were central to this progress. Although a causal link to the reduction of child mortality was not possible to establish, we saw evidence of temporal association and biological plausibility to the high level of coverage of public health interventions, as well as significant association to the investments in women education, social protection, water, and sanitation. Leadership and continuity of public health policies, along with investments on institutions and human resources strengthening, were also among the reasons for these achievements.

  1. Improvement of child survival in Mexico: the diagonal approach.

    Science.gov (United States)

    Sepúlveda, Jaime; Bustreo, Flavia; Tapia, Roberto; Rivera, Juan; Lozano, Rafael; Oláiz, Gustavo; Partida, Virgilio; García-García, Lourdes; Valdespino, José Luis

    2006-12-01

    Public health interventions aimed at children in Mexico have placed the country among the seven countries on track to achieve the goal of child mortality reduction by 2015. We analysed census data, mortality registries, the nominal registry of children, national nutrition surveys, and explored temporal association and biological plausibility to explain the reduction of child, infant, and neonatal mortality rates. During the past 25 years, child mortality rates declined from 64 to 23 per 1000 livebirths. A dramatic decline in diarrhoea mortality rates was recorded. Polio, diphtheria, and measles were eliminated. Nutritional status of children improved significantly for wasting, stunting, and underweight. A selection of highly cost-effective interventions bridging clinics and homes, what we called the diagonal approach, were central to this progress. Although a causal link to the reduction of child mortality was not possible to establish, we saw evidence of temporal association and biological plausibility to the high level of coverage of public health interventions, as well as significant association to the investments in women education, social protection, water, and sanitation. Leadership and continuity of public health policies, along with investments on institutions and human resources strengthening, were also among the reasons for these achievements.

  2. On the Gravitational Energy Associated with Spacetimes of Diagonal Metric

    CERN Document Server

    Korunur, M; Salti, M; Korunur, Murat; Havare, Ali; Salti, Mustafa

    2006-01-01

    In order to evaluate the energy distribution (due to matter and fields including gravitation) associated with a spacetime model of generalized diagonal metric, we consider the Einstein, Bergmann-Thomson and Landau-Lifshitz energy and/or momentum definitions both in Einstein's theory of general relativity and the teleparallel gravity (the tetrad theory of gravitation). We find the same energy distribution using Einstein and Bergmann-Thomson formulations, but we also find that the energy-momentum prescription of Landau-Lifshitz disagree in general with these definitions. We also give eight different well-known spacetime models as examples, and considering these models and using our results, we calculate the energy distributions associated with them. Furthermore, we show that for the Bianci type-I all the formulations give the same result. This result agrees with the previous works of Cooperstock-Israelit, Rosen, Johri {\\it et al.}, Banerjee-Sen, Xulu, Vargas and Salt{\\i} {\\it et al.} and supports the viewpoints...

  3. Efficient Numerical Diagonalization of Hermitian 3 × 3 Matrices

    Science.gov (United States)

    Kopp, Joachim

    A very common problem in science is the numerical diagonalization of symmetric or hermitian 3 × 3 matrices. Since standard "black box" packages may be too inefficient if the number of matrices is large, we study several alternatives. We consider optimized implementations of the Jacobi, QL, and Cuppen algorithms and compare them with an alytical method relying on Cardano's formula for the eigenvalues and on vector cross products for the eigenvectors. Jacobi is the most accurate, but also the slowest method, while QL and Cuppen are good general purpose algorithms. The analytical algorithm outperforms the others by more than a factor of 2, but becomes inaccurate or may even fail completely if the matrix entries differ greatly in magnitude. This can mostly be circumvented by using a hybrid method, which falls back to QL if conditions are such that the analytical calculation might become too inaccurate. For all algorithms, we give an overview of the underlying mathematical ideas, and present detailed benchmark results. C and Fortran implementations of our code are available for download from .

  4. Variant position of the medial plantar nerve

    Directory of Open Access Journals (Sweden)

    Astik RB

    2011-01-01

    Full Text Available Knowledge of variation of position of the medial plantar nerve is important for the forefoot surgeon for plantar reconstruction, local injection therapy and an excision of interdigital neuroma. During routine dissection of 50-year-old female cadaver, we found the medial plantar nerve and vessels variably located between plantar aponeurosis and the muscles of the first layer of the sole of the right foot. Due to this variant position, the medial plantar nerve and vessels lose their protection from the muscles of the first layer of the sole of the foot and became vulnerable for compression.

  5. Medial talo-calcaneal coalition. Case report

    Energy Technology Data Exchange (ETDEWEB)

    Daly, B.D.; Towers, M.J.; Hamilton, S.

    1988-11-01

    Medial talo-calcaneal coalition is an uncommon developmental anomaly consisting of a bony projection arising from the postero-medial aspect of the sustentaculum tali, which may articulate with another bony projection from the medial aspect of the talus. Fibrous, cartilaginous or bony ankylosis may occur. It usually presents in adolescents, and causes pain following exercise. It may cause a lump, and can predispose to flat foot and early osteoarthrosis. This condition is easily overlooked on routine views of the ankle, and may require oblique views and tomography for its detection and clarification.

  6. Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus.

    Science.gov (United States)

    Pombero, Ana; Bueno, Carlos; Saglietti, Laura; Rodenas, Monica; Guimera, Jordi; Bulfone, Alexandro; Martinez, Salvador

    2011-10-01

    The majority of the cortical cholinergic innervation implicated in attention and memory originates in the nucleus basalis of Meynert and in the horizontal limb of the diagonal band nucleus of the basal prosencephalon. Functional alterations in this system give rise to neuropsychiatric disorders as well as to the cognitive alterations described in Parkinson and Alzheimer's diseases. Despite the functional importance of these basal forebrain cholinergic neurons very little is known about their origin and development. Previous studies suggest that they originate in the medial ganglionic eminence of the telencephalic subpallium; however, our results identified Tbr1-expressing, reelin-positive neurons migrating from the ventral pallium to the subpallium that differentiate into cholinergic neurons in the basal forebrain nuclei projecting to the cortex. Experiments with Tbr1 knockout mice, which lack ventropallial structures, confirmed the pallial origin of cholinergic neurons in Meynert and horizontal diagonal band nuclei. Also, we demonstrate that Fgf8 signaling in the telencephalic midline attracts these neurons from the pallium to follow a tangential migratory route towards the basal forebrain.

  7. Sub-Ohmic spin-boson model with off-diagonal coupling: ground state properties.

    Science.gov (United States)

    Lü, Zhiguo; Duan, Liwei; Li, Xin; Shenai, Prathamesh M; Zhao, Yang

    2013-10-28

    We have carried out analytical and numerical studies of the spin-boson model in the sub-ohmic regime with the influence of both the diagonal and the off-diagonal coupling accounted for, via the Davydov D1 variational ansatz. While a second-order phase transition is known to be exhibited by this model in the presence of diagonal coupling only, we demonstrate the emergence of a discontinuous first order phase transition upon incorporation of the off-diagonal coupling. A plot of the ground state energy versus magnetization highlights the discontinuous nature of the transition between the isotropic (zero magnetization) state and nematic (finite magnetization) phases. We have also calculated the entanglement entropy and a discontinuity found at a critical coupling strength further supports the discontinuous crossover in the spin-boson model in the presence of off-diagonal coupling. It is further revealed via a canonical transformation approach that for the special case of identical exponents for the spectral densities of the diagonal and the off-diagonal coupling, there exists a continuous crossover from a single localized phase to doubly degenerate localized phase with differing magnetizations.

  8. [The application of the nanostructured bioplastic material for the plastic reconstruction of perforations in the nasal septum].

    Science.gov (United States)

    Grigor'eva, M V; Akimov, A V; Bagautdinov, A A

    2014-01-01

    The objective of the present work was to estimate the effectiveness of the application of the nanostructured bioplastic material for the plastic reconstruction of perforations in the nasal septum. A total of 80 patients were recruited for the study. Half of them underwent plastic reconstruction of perforations in the nasal septum with the application of the nanostructured bioplastic material. Forty patients were treated using no biotransplants. The functional state of nasal cavity mucosa was evaluated before and after surgery. It is concluded that the nanostructured bioplastic material used in the present study ensures efficacious reconstruction of nasal septum integrity after plastic correction of septal perforations.

  9. The Pulsed Power Converter and Septum Magnet System for Injection into the Electron Storage Ring at ESRF

    CERN Document Server

    Perrine, J P; Völker, F V

    1996-01-01

    At ESRF, the European Synchrotron Radiation Facility in Grenoble, electrons are accelerated, via a 200 MeV Linac and a 6 GeV synchrotron booster, and injected into the storage ring at 10 Hz rate. Two thin septum blade magnets and an eddy current sheet type septum magnet provide the final deflection of the injected beam. The operational requirements of the e- injection scheme and the resulting demanding hardware specifications are recalled. The pulsed septum magnets are briefly described. The design, circuit layout and construction of the power converters are related with emphasis on innovative aspects of general interest. Results of tests during commissioning are reported.

  10. Morphological interaction between the nasal septum and nasofacial skeleton during human ontogeny.

    Science.gov (United States)

    Goergen, Matthew J; Holton, Nathan E; Grünheid, Thorsten

    2017-02-20

    The nasal septal cartilage is thought to be a key growth center that contributes to nasofacial skeletal development. Despite the developmental influence of the nasal septum however, humans often exhibit a high frequency of septal deviation suggesting discordance in the growth between the septum and surrounding nasofacial skeleton. While there are numerous etiological factors that contribute to septal deviation, the surrounding nasofacial skeleton may also act to constrain the septum, resulting in altered patterns of growth. That is, while the nasal septum has a direct morphogenetic influence on aspects of the nasofacial skeleton, other nasofacial skeletal components may restrict septal growth resulting in deviation. Detailing the developmental relationship between these structures is important not only for understanding the causal determinants of nasal septal deviation, but also for developing a broader understanding of the complex interaction between the facial skeleton and chondrocranium. We selected 66 non-syndromic subjects from the University of Minnesota Orthodontic Clinic who ranged from 7 to 18 years in age and had an existing pretreatment cone-beam computed tomography (CBCT) scan. Using CBCT data, we examined the developmental relationship between nasal septal deviation and the surrounding nasofacial skeleton. We measured septal deviation as a percentage of septal volume relative to a modeled non-deviated septum. We then collected a series of coordinate landmark data in the region immediately surrounding the nasal septum in the midsagittal plane representing the nasofacial skeleton. First, we examined ontogenetic changes in the magnitude of nasal septal deviation relative to chronological age and nasofacial size. Next, using Procrustes-based geometric morphometric techniques, we assessed the morphological relationship between nasal septal deviation and nasofacial skeletal shape. Our results indicate that variation in the magnitude of nasal septal

  11. [Tibial periostitis ("medial tibial stress syndrome")].

    Science.gov (United States)

    Fournier, Pierre-Etienne

    2003-06-01

    Medial tibial stress syndrome is characterised by complaints along the posteromedial tibia. Runners and athletes involved in jumping activities may develop this syndrome. Increased stress to stabilize the foot especially when excessive pronation is present explain the occurrence this lesion.

  12. Medial and Lateral Plantar Nerve Entrapment

    Science.gov (United States)

    ... Foot Problems Overview of Foot Problems Achilles Tendon Bursitis Achilles Tendon Enthesopathy Bunion Corns and Calluses Damage ... the Foot Freiberg Disease Hammer Toe Inferior Calcaneal Bursitis Medial and Lateral Plantar Nerve Entrapment Metatarsal Joint ...

  13. Comparative study on diagonal equivalent methods of masonry infill panel

    Science.gov (United States)

    Amalia, Aniendhita Rizki; Iranata, Data

    2017-06-01

    ratio of height to width of 1 to 1.5. Load used in the experiment was based on Uniform Building Code (UBC) 1991. Every method compared was calculated first to get equivalent diagonal strut width. The second step was modelling method using structure analysis software as a frame with a diagonal in a linear mode. The linear mode was chosen based on structure analysis commonly used by structure designers. The frame was loaded and for every model, its load and deformation values were identified. The values of load - deformation of every method were compared to those of experimental test specimen by Mehrabi and open frame. From comparative study performed, Holmes' and Bazan-Meli's equations gave results the closest to the experimental test specimen by Mehrabi. Other equations that gave close values within the limit (by comparing it to the open frame) are Saneinejad-Hobbs, Stafford-Smith, Bazan-Meli, Liauw Kwan, Paulay and Priestley, FEMA 356, Durani Luo, Hendry, Papia and Chen-Iranata.

  14. UMAPRM: Uniformly sampling the medial axis

    KAUST Repository

    Yeh, Hsin-Yi Cindy

    2014-05-01

    © 2014 IEEE. Maintaining clearance, or distance from obstacles, is a vital component of successful motion planning algorithms. Maintaining high clearance often creates safer paths for robots. Contemporary sampling-based planning algorithms That utilize The medial axis, or The set of all points equidistant To Two or more obstacles, produce higher clearance paths. However, They are biased heavily Toward certain portions of The medial axis, sometimes ignoring parts critical To planning, e.g., specific Types of narrow passages. We introduce Uniform Medial Axis Probabilistic RoadMap (UMAPRM), a novel planning variant That generates samples uniformly on The medial axis of The free portion of Cspace. We Theoretically analyze The distribution generated by UMAPRM and show its uniformity. Our results show That UMAPRM\\'s distribution of samples along The medial axis is not only uniform but also preferable To other medial axis samplers in certain planning problems. We demonstrate That UMAPRM has negligible computational overhead over other sampling Techniques and can solve problems The others could not, e.g., a bug Trap. Finally, we demonstrate UMAPRM successfully generates higher clearance paths in The examples.

  15. A newly identified frontal path from fornix in septum pellucidum with 7.0T MRI track density imaging (TDI – The septum pellucidum tract (SPT

    Directory of Open Access Journals (Sweden)

    Zang-Hee eCho

    2015-11-01

    Full Text Available The high anatomical contrast achieved with the newly emerging MRI tractographic technique of super-resolution track density imaging (TDI encouraged us to search for a new fiber tract in the septum pellucidum. Although this septum pellucidum tract (SPT has been observed previously, its connections were unclear due to ambiguity and limited resolution of conventional MRI images. It is now possible to identify detailed parts of SPT with the increased resolution of TDI, which involves diffusion MRI imaging, whole-brain tractography, and voxel subdivision using the track-count information. Four healthy male subjects were included in the study. The experiment was performed with 7.0T MRI, following the guidelines of the institute’s institutional review board. Data were processed with the super-resolution TDI technique to generate a tractographic map with 0.18 mm isotropic resolution. The SPT was identified in all subjects. Based on additional seed tracking method with inter-axis correlation search, we have succeeded in identifying a new frontal lobe pathway in the SPT. We hypothesize that the tract is connected as a superior dorsal branch of the fornix that leads to the prefrontal cortex.

  16. Development of magnetic leakage shield of septum magnet for SPring-8 synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Abe, Hiroshi; Aoki, Tsuyoshi [Japan Atomic Energy Research Inst., Kamigori, Hyogo (Japan). Kansai Research Establishment; Ueyama, Yasuo [and others

    1997-10-01

    This paper describes magnetic field measurements of the prototype septum magnet and countermeasure for reducing the leakage magnetic fields in the incidence and the extraction parts of the SPring-8 synchrotron. We studied and developed `Magnetic Leakage Shield` on the basis of many tests data got in these measurements. Consequentially, it succeeded in reducing effects of the leakage field to about 70% by installing the shield board in the magnet main body. Then, it was possible to manufacture the magnet which sufficiently held the effect of the leakage field for the electron and positron beam. In this examination, we confirmed the reproduction with the magnetic field distribution of the magnet measured in the manufacturer. We developed and produced of the septum magnets which were carried out determination of the shapes of the magnetic shielding. (author)

  17. [Innervation of the atrioventricular portion of the interatrial septum in the rat].

    Science.gov (United States)

    Pavlovich, E R

    1984-03-01

    A quantitative electron microscopical investigation has revealed reliable differences in contents of muscular, connective tissue and neural elements in the conductive system, on the one hand (in the atrioventricular node and in the internodal specialized pathways) and in the working myocardium of the inferior third of the interatrial septum, on the other hand. Morphometrical analysis of the neuromuscular interrelations, performed separately for every type of specialized conductive myocytes (II, III) and of working cardiomyocytes of the interatrial septum, reveals some differences in size of the neural fibers and their terminals and in distance between them and myocytes. The synaptic vesicles of the efferent terminals are qualitatively different in all types of the myocytes. The afferent terminals situating near specialized cardiac cells are characterized. Criteria for distinguishing small and large granular vesicles in the terminals are discussed. A suggestion is made that the innervational peculiarities revealed reflect certain specificity in regulation the conduction in the atrioventricular area of the heart.

  18. High field septum magnet using a superconducting shield for the Future Circular Collider

    CERN Document Server

    AUTHOR|(CDS)2069375

    2017-01-01

    A zero-field cooled superconducting shield is proposed to realize a high-field (3–4 T) septum magnet for the Future Circular Collider hadron-hadron (FCC-hh) ring. Three planned prototypes using different materials and technical solutions are presented, which will be used to evaluate the feasibility of this idea as a part of the FCC study. The numerical simulation methods are described to calculate the field patterns around such a shield. A specific excitation current configuration is presented that maintains a fairly homogeneous field outside of a rectangular shield in a wide range of field levels from 0 to 3 Tesla. It is shown that a massless septum configuration (with an opening in the shield) is also possible and gives satisfactory field quality with realistic superconducting material properties.

  19. Pitfalls in Cytodiagnosis of Pleomorphic Adenoma of the Nasal Septum - A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Abhishek MG

    2010-10-01

    Full Text Available Pleomorphic adenoma is the most common benign mixed tumor of major salivary gland. Ectopic occurrence of pleomorphic adenoma are seen in minor salivary glands of pharynx, trachea, larynx and very rarely in nasal septum. We report a case of 40 year old female who presented with right sided nasal mass and mild nasal obstruction since six months. Cytologically a possibility of pleomorphic adenoma was made which was confirmed by histopathological study. We present this case due to 1 rarity in the nasal septum 2 pitfalls at cytology due to abundance (predominance of myoepithelial cells and scanty or even absent mesenchymal component and 3 under reporting in English literature to the best of our knowledge.

  20. Persistent Truncus Arteriosus With Intact Ventricular Septum: Clinical, Hemodynamic and Short-term Surgical Outcome

    Directory of Open Access Journals (Sweden)

    Gholamhossein Ajami

    2015-10-01

    Full Text Available Introduction: Truncus arteriosus with intact ventricular septum is a rare and unique variant of persistent truncus arteriosus (PTA which usually presents with central cyanosis and congestive heart failure in neonate and early infancy. Associated cardiac and non-cardiac anomalies may affect morbidity and mortality of these patients. Case Presentation: We describe clinical presentation, echocardiography and angiographic features of a 7-month old boy with PTA and intact ventricular septum who underwent surgical repair of the anomaly at our institution. Operative findings, surgical procedure and short-term outcome are reported. Conclusions: While our patient had systemic pulmonary arterial pressure at the time of complete surgical repair, it was improved after surgery.

  1. GABAA receptor signaling in the lateral septum regulates maternal aggression in mice

    OpenAIRE

    2009-01-01

    Maternal aggression (maternal defense) is a fierce aggression produced by lactating females towards intruders that plays an important role in protection of vulnerable offspring. Enhancement of GABAA receptor signaling by benzodiazepines increases maternal aggression and we recently found indirect evidence that lateral septum (LS) could be a key site where benzodiazepines elevate aggression. In this study, we directly tested the hypothesis that activation of GABAA receptors in LS would promote...

  2. Lupus vulgaris leading to perforation of nasal septum in a child.

    Science.gov (United States)

    Singal, Archana; Arora, Rahul; Pandhi, Deepika

    2015-01-01

    Lupus vulgaris (LV) is a common form of cutaneous tuberculosis in India, mostly involving the lower half of the body. Facial involvement is uncommon. Untreated disease may lead to significant morbidity due to atrophic scarring, mutilation, and deformity. We report a case of multi-focal LV in a 10-year-old boy affecting the nose and cheek that resulted in perforation of the nasal septum, a rarely reported complication.

  3. The steel septum magnets for beam splitting at the CERN SPS

    CERN Document Server

    Evans, Lyndon R; de Raad, Bastiaan; Thomi, W; Weisse, E

    1978-01-01

    Each of the two slow-extracted proton beams of the CERN 400 GeV Super Proton Synchrotron can be divided into three parts by means of steel- septum magnets for the simultaneous irradiation of up to three production targets. The magnets have radiation-proof coils, integrated vacuum chambers and 'plug-in' connections. The paper describes the design of the magnets and gives the results of the magnetic field measurements. (3 refs).

  4. Large Right Ventricular Clot in Pulmonary Atresia With Intact Ventricular Septum: In Defense of Biventricular Approach.

    Science.gov (United States)

    Dutta, Nilanjan; Ghosh, Rajarshi; Awasthy, Neeraj; Iyer, Parvathi U; Girotra, Sumir; Iyer, Krishna S

    2016-09-01

    Thrombus formation within the right ventricle (RV) in the setting of pulmonary atresia with intact ventricular septum (PAIVS) is not a very common occurrence and can be catastrophic. We present the case of a seven-month-old child with PAIVS and RV clot who successfully underwent biventricular repair. We discuss the interesting case and the rationale for management by means of biventricular repair over single ventricle repair when feasible in such a setting.

  5. A CASE OF OPEN LIP SCHIZENCEPHALY ASSOCIATED WITH ABSENT SEPTUM PELLUCIDUM AND ARACHNOID CYST

    Directory of Open Access Journals (Sweden)

    Chris

    2014-07-01

    Full Text Available Schizencephaly (spilt brain is an uncommon disorder of cerebral cortical development, characterized by congenital clefts spanning the cerebral hemispheres from the pial surface to the lateral ventricles and lined by dysplastic cortical gray matter, the condition is present at birth and present early in life. Here we present an adult patient of open lip schizencephaly associated with absent septum pellucidum and arachnoid cyst presenting with seizure on and off for past four years.

  6. Preventing lesions of nasal septum in preterm newborns: an integrative literature review

    OpenAIRE

    Suely de Fátima Santos Freire Bonfim; Simone Maria Muniz da Silva Bezerra; Maria Gorete Lucena de Vasconcelos; Luciana Pedrosa Leal

    2014-01-01

    The goal of this study is to investigate scientific evidence related to nursing care for preventing lesions of the nasal septum in preterm infants who are using nasal prong ventilation.  It is an integrative literature review through LILACS, BDENF, CINAHAL, PUBMED and SciELO library electronic databases. We selected 09 studies between 2000 and 2013, available online or through the author, published in Portuguese, English and Spanish. The results displayed that 70% of the studies examine the q...

  7. A Summary of Design Formulas for Beams Having Thin Webs in Diagonal Tension

    Science.gov (United States)

    Kuhn, Paul

    1933-01-01

    This report presents an explanation of the fundamental principles and a summary of the essential formulas for the design of diagonal-tension field beams, i.e. beams with very thin webs, as developed by Professor Wagner of Germany.

  8. Asymptotic correctability of Bell-diagonal quantum states and maximum tolerable bit error rates

    CERN Document Server

    Ranade, K S; Ranade, Kedar S.; Alber, Gernot

    2005-01-01

    The general conditions are discussed which quantum state purification protocols have to fulfill in order to be capable of purifying Bell-diagonal qubit-pair states, provided they consist of steps that map Bell-diagonal states to Bell-diagonal states and they finally apply a suitably chosen Calderbank-Shor-Steane code to the outcome of such steps. As a main result a necessary and a sufficient condition on asymptotic correctability are presented, which relate this problem to the magnitude of a characteristic exponent governing the relation between bit and phase errors under the purification steps. These conditions allow a straightforward determination of maximum tolerable bit error rates of quantum key distribution protocols whose security analysis can be reduced to the purification of Bell-diagonal states.

  9. Free field approach to diagonalization of boundary transfer matrix : recent advances

    CERN Document Server

    Kojima, Takeo

    2011-01-01

    We diagonalize infinitely many commuting operators $T_B(z)$. We call these operators $T_B(z)$ the boundary transfer matrix associated with the quantum group and the elliptic quantum group. The boundary transfer matrix is related to the solvable model with a boundary. When we diagonalize the boundary transfer matrix, we can calculate the correlation functions for the solvable model with a boundary. We review the free field approach to diagonalization of the boundary transfer matrix $T_B(z)$ associated with $U_q(A_2^{(2)})$ and $U_{q,p}(\\hat{sl_N})$. We construct the free field realizations of the eigenvectors of the boundary transfer matrix $T_B(z)$. This paper includes new unpublished formula of the eigenvector for $U_q(A_2^{(2)})$. It is thought that this diagonalization method can be extended to more general quantum group $U_q(g)$ and elliptic quantum group $U_{q,p}(g)$.

  10. Localization in band random matrix models with and without increasing diagonal elements.

    Science.gov (United States)

    Wang, Wen-ge

    2002-06-01

    It is shown that localization of eigenfunctions in the Wigner band random matrix model with increasing diagonal elements can be related to localization in a band random matrix model with random diagonal elements. The relation is obtained by making use of a result of a generalization of Brillouin-Wigner perturbation theory, which shows that reduced Hamiltonian matrices with relatively small dimensions can be introduced for nonperturbative parts of eigenfunctions, and by employing intermediate basis states, which can improve the method of the reduced Hamiltonian matrix. The latter model deviates from the standard band random matrix model mainly in two aspects: (i) the root mean square of diagonal elements is larger than that of off-diagonal elements within the band, and (ii) statistical distributions of the matrix elements are close to the Lévy distribution in their central parts, except in the high top regions.

  11. QUASI-DIAGONALIZATION FOR A SINGULARLY PERTURBED DIFFERENTIAL SYSTEM WITH TWO PARAMETERS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    By two successive linear transformations,a singularly perturbed differential system with two parameters is quasi-diagonalized. The method of variation of constants and the principle of contraction map are used to prove the existence of the transformations.

  12. 线性变换对角化问题浅析%Diagonalization of Linear Transformation

    Institute of Scientific and Technical Information of China (English)

    王玉梅

    2011-01-01

    For the linear transform and matrix diagonalization diagonalization similar to the link between the easily understood by matrix diagonalization to study the relative complexity of diagonalization of the linear transformation, and then by studying the eige%对于线性变换对角化与矩阵相似对角化之间的联系,通过对易理解的矩阵的对角化问题来研究相对复杂线性变换的对角化问题,然后通过研究特征值与特征向量的性质,再研究对角化的必要条件与充分条件,从而更轻松的理解并掌握线性变换的对角化问题。

  13. Three dimensional color Doppler transvaginal ultrasound morphologic features of uterine septum and residual cavity in women with reproductive failure

    Directory of Open Access Journals (Sweden)

    Somayya M. Sadek

    2015-03-01

    Conclusion: 3D US plays a valuable role in the assessment of morphologic characters of uterine septum and the calculation of the residual cavity volume. Septal length followed by width is a significant variable that affects reproductive outcome.

  14. [Aneurysms of the interauricular septum. Review of the literature apropos of 8 cases].

    Science.gov (United States)

    Herpin, D; Ciber, M A; Boutaud, P; Amiel, A; Gaudeau, B; Guillem, J P; Demange, J

    1986-01-01

    The authors present 8 cases of aneurysms of the interauricular septum (AIAS). The diagnosis was established in all cases by two-dimensional echocardiography (E2D) which was requested, three times following a cerebral vascular accident (CVA). The AIAS manifest themselves as localised "hernias" of the inter-auricular septum, mobile during the cardiac cycle. Their topography was strictly right inter-auricular in 6 cases, whereas in the other 2 patients the AIAS passed into the left atrium at protosystole and returned to the right atrium at telesystole. Catheterization with angiography was carried out 5 times: the inter-auricular septum was crossed 4 times without gasometric reasons for an associated shunt; the AIAS was opacified in all cases. An anti-coagulant treatment was prescribed for 3 patients who had suffered a CVA, and for a fourth presenting numerous supraventricular extrasystoles which were sometimes grouped. A review of the literature of the last fifty years enabled a compilation of 93 cases of AIAS to be made, 49 of which had been examined by E2D, 35 had had a hemodynamic and angiographic exploration and 47 an anatomical and/or surgical confirmation. The main results obtained are described and commented on. The diagnostic, etiopathological and prognostic problems raised by the "updating" of this pathology are discussed.

  15. Enhanced chondrogenesis of human nasal septum derived progenitors on nanofibrous scaffolds

    Energy Technology Data Exchange (ETDEWEB)

    Shafiee, Abbas [Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Stem Cell biology and Tissue Engineering Departments, Stem Cell Technology Research Center, Tehran (Iran, Islamic Republic of); Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD (Australia); Seyedjafari, Ehsan [Department of Biotechnology, College of Science, University of Tehran, Tehran (Iran, Islamic Republic of); Sadat Taherzadeh, Elham [Stem Cell biology and Tissue Engineering Departments, Stem Cell Technology Research Center, Tehran (Iran, Islamic Republic of); Dinarvand, Peyman [Stem Cell biology and Tissue Engineering Departments, Stem Cell Technology Research Center, Tehran (Iran, Islamic Republic of); The Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO (United States); Soleimani, Masoud [Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran (Iran, Islamic Republic of); Ai, Jafar, E-mail: jafar_ai@tums.ac.ir [Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Brain and Spinal Injury Research Center, Imam Hospital, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of)

    2014-07-01

    Topographical cues can be exploited to regulate stem cell attachment, proliferation, differentiation and function in vitro and in vivo. In this study, we aimed to investigate the influence of different nanofibrous topographies on the chondrogenic differentiation potential of nasal septum derived progenitors (NSP) in vitro. Aligned and randomly oriented Ploy (L-lactide) (PLLA)/Polycaprolactone (PCL) hybrid scaffolds were fabricated via electrospinning. First, scaffolds were fully characterized, and then NSP were seeded on them to study their capacity to support stem cell attachment, proliferation and chondrogenic differentiation. Compared to randomly oriented nanofibers, aligned scaffolds showed a high degree of nanofiber alignment with much better tensile strength properties. Both scaffolds supported NSP adhesion, proliferation and chondrogenic differentiation. Despite the higher rate of cell proliferation on random scaffolds, a better chondrogenic differentiation was observed on aligned nanofibers as deduced from higher expression of chondrogenic markers such as collagen type II and aggrecan on aligned scaffolds. These findings demonstrate that electrospun constructs maintain NSP proliferation and differentiation, and that the aligned nanofibrous scaffolds can significantly enhance chondrogenic differentiation of nasal septum derived progenitors. - Highlights: • Electrospun nanofiber scaffolds with different topographies were fabricated. • Aligned nanofiber scaffolds had better tensile strength properties. • Nasal septum derived progenitors were cultured on nanofibrous scaffolds. • Both topographies support proliferation and chondrogenic differentiation. • Better chondrogenic differentiation was observed on aligned nanofibers.

  16. Diagonal Kernel Point Estimation of th-Order Discrete Volterra-Wiener Systems

    Directory of Open Access Journals (Sweden)

    Pirani Massimiliano

    2004-01-01

    Full Text Available The estimation of diagonal elements of a Wiener model kernel is a well-known problem. The new operators and notations proposed here aim at the implementation of efficient and accurate nonparametric algorithms for the identification of diagonal points. The formulas presented here allow a direct implementation of Wiener kernel identification up to the th order. Their efficiency is demonstrated by simulations conducted on discrete Volterra systems up to fifth order.

  17. Total correlations of the diagonal ensemble as a generic indicator for ergodicity breaking in quantum systems

    OpenAIRE

    Pietracaprina, Francesca; Gogolin, Christian; Goold, John

    2016-01-01

    The diagonal ensemble is the infinite time average of a quantum state following unitary dynamics. In analogy to the time average of a classical phase space dynamics, it is intimately related to the ergodic properties of the quantum system giving information on the spreading of the initial state in the eigenstates of the Hamiltonian. In this work we apply a concept from quantum information, known as total correlations, to the diagonal ensemble. Forming an upper-bound on the multipartite entang...

  18. The Spectrum and the Spectral Type of the Off-Diagonal Fibonacci Operator

    CERN Document Server

    Damanik, David

    2008-01-01

    We consider Jacobi matrices with zero diagonal and off-diagonals given by elements of the hull of the Fibonacci sequence and show that the spectrum has zero Lebesgue measure and all spectral measures are purely singular continuous. In addition, if the two hopping parameters are distinct but sufficiently close to each other, we show that the spectrum is a dynamically defined Cantor set, which has a variety of consequences for its local and global fractal dimension.

  19. Distilling perfect GHZ states from two copies of non-GHZ-diagonal mixed states

    Science.gov (United States)

    Wang, Xin-Wen; Tang, Shi-Qing; Yuan, Ji-Bing; Zhang, Deng-Yu

    2017-06-01

    It has been shown that a nearly pure Greenberger-Horne-Zeilinger (GHZ) state could be distilled from a large (even infinite) number of GHZ-diagonal states that can be obtained by depolarizing general multipartite mixed states (non-GHZ-diagonal states) through sequences of (probabilistic) local operations and classical communications. We here demonstrate that perfect GHZ states can be extracted, with certain probabilities, from two copies of non-GHZ-diagonal mixed states when some conditions are satisfied. This result implies that it is not necessary to depolarize these entangled mixed states to the GHZ-diagonal type, and that they are better than GHZ-diagonal states for distillation of pure GHZ states. We find a wide class of multipartite entangled mixed states that fulfill the requirements. Moreover, we display that the obtained result can be applied to practical noisy environments, e.g., amplitude-damping channels. Our findings provide an important complementarity to conventional GHZ-state distillation protocols (designed for GHZ-diagonal states) in theory, as well as having practical applications.

  20. In Vivo Imaging Reveals Composite Coding for Diagonal Motion in the Drosophila Visual System

    Science.gov (United States)

    Zhou, Wei; Chang, Jin

    2016-01-01

    Understanding information coding is important for resolving the functions of visual neural circuits. The motion vision system is a classic model for studying information coding as it contains a concise and complete information-processing circuit. In Drosophila, the axon terminals of motion-detection neurons (T4 and T5) project to the lobula plate, which comprises four regions that respond to the four cardinal directions of motion. The lobula plate thus represents a topographic map on a transverse plane. This enables us to study the coding of diagonal motion by investigating its response pattern. By using in vivo two-photon calcium imaging, we found that the axon terminals of T4 and T5 cells in the lobula plate were activated during diagonal motion. Further experiments showed that the response to diagonal motion is distributed over the following two regions compared to the cardinal directions of motion—a diagonal motion selective response region and a non-selective response region—which overlap with the response regions of the two vector-correlated cardinal directions of motion. Interestingly, the sizes of the non-selective response regions are linearly correlated with the angle of the diagonal motion. These results revealed that the Drosophila visual system employs a composite coding for diagonal motion that includes both independent coding and vector decomposition coding. PMID:27695103

  1. Diagonal Loading of Robust General-Rank Beamformer for Direction of Arrival Mismatch

    Directory of Open Access Journals (Sweden)

    Z.U. Khan

    2013-05-01

    Full Text Available This study presents a technique which utilizes the movement of the peak of the main beam towards the presumed signal direction with negative diagonal loading for robust general-rank beamformer. The main beam symmetry along presumed signal direction is improved by this movement. When desired signal is contained in the data snapshots, the conventional beamformers face the problem of performance degradation even if there is a small mismatch between the presumed and the actual signal direction. Diagonal loading is a popular technique to mitigate this problem. There is no definite criterion to find diagonal loading level. A new diagonal loading method has been proposed in the literature which utilizes the movement of the peak of main beam towards the presumed signal direction with positive diagonal loading. The proposed technique works iteratively for the selection of negative diagonal loading level to move the main beam at a position to get the beam symmetry at desired level and hence the desired robustness. The mismatched signal will not be cancelled as long as it is within the half of the width of the main beam. But there is the tradeoff between this robustness and interference cancelling capability.

  2. An Aneurysmal Interatrial Septum with a Patent Foramen Ovale and Multiple Fenestrations Closed by A Single Occluder Device

    Directory of Open Access Journals (Sweden)

    Mandana Chitsazan

    2012-10-01

    Full Text Available The patent foramen ovale (PFO usually is a very small potential opening in the atrial septum. Under the conditions of normal hemodynamics with higher left atrial than right atrial pressures, the septum primum is forced against the foramen by the higher left atrial pressure and there is no actual persistent opening through the foramen. However, with any, even transient, increase in right atrial pressure this flap or "valve" can be pushed away from the septum and forced open. This results in the shunting of blood and anything else in the right atrium from the right atrium to the left atrium. Often the "valve" of the foramen becomes redundant and develops an "aneurysm" of the atrial septum. A large, redundant septum primum can have several additional openings or "fenestrations" in it. The PFO is now can be treated by interventional percutaneous therapy. This case represents a 24-year-old male with an aneurysmal interatrial septum and patent foramen ovale associated with multiple fenestrations. The defects were closed by a single Amplatzer® septal occluder.

  3. Medial meniscal cyst: a case report.

    Science.gov (United States)

    Spina, Mauro; Sabbioni, Giacomo; Tigani, Domenico

    2008-12-01

    Meniscal cysts are a rare disease constantly combined with a horizontal meniscal lesion. Currently, nuclear magnetic resonance (MRI) is the main diagnostic tool, because of its high sensitivity and specificity, and decompression arthroscopy combined with selective meniscectomy is the treatment of choice. The Authors report a case of a voluminous medial meniscal cyst where instrumental examination, MRI, was fundamental for the preoperative diagnosis of the horizontal meniscal lesion causing the cystic degeneration of the meniscus. The treatment performed was selective meniscectomy of the body and posterior horn of the medial meniscus and decompression of the voluminous cyst by arthroscopy. Physical examination after six months showed the complete resolution of swelling at the medial hemirima, no walking pain and normal range of motion.

  4. The localization of the distal perforators of posterior tibial artery: a cadaveric study for the correct planning of medial adipofascial flaps.

    Science.gov (United States)

    Bulla, A; De Luca, L; Campus, G V; Rubino, C; Montella, A; Casoli, V

    2015-01-01

    The adipofascial flap, introduced by Lin in 1994, has many advantages compared to fasciocutaneous or free flaps. Its dissection is relatively easy and fast with low donor-site morbidity, and it does not alter the shape of the leg. The aim of this dissection study is to evaluate the anatomic localization of the most distal perforator of the posterior tibial vessels to provide an anatomical rationale for the safe harvesting of distally based medial adipofascial flaps of the leg. 30 Lower limbs from 15 cadavers were used for this study. The most distal perforator from posterior tibial perforator artery, accompanied by at least one vein, was identified and its distance from the medial malleolus was noted. A distal perforator was found in all specimens; the mean caliber was 0.77 mm. In all cases, the perforator artery passed in the septum between flexor hallucis longus m. and flexor digitorum longus m. and was accompanied by two veins. In our series, the distance between the lowest perforator and the medial malleolus ranged from 3.5 to 8.2 cm. The median was 6.75 cm, the 5th percentile 4 cm and the 95th percentile 8.1 cm. The mean distance of the perforator from the medial tibial border was 1.23 cm. The mean ratio between the distance of perforator from the medial malleolus and the total leg length was 21%. Compared to all previous researches, our study has found more distal perforators from posterior tibial perforator artery. This fact may have important clinical consequences, because the anteromedial adipofascial flap would cover more distal soft tissue defects. Moreover, our data suggest some safety parameters to make the rising of a medial adipofascial leg flap safer in surgical practice.

  5. Lightning Surge Analysis Including Diagonal Wires Based on the FDTD Method

    Science.gov (United States)

    Yamamoto, Kazuo; Iki, Hiroyuki

    This paper presents an arbitrary diagonal wire on an rectangular surface composing a cubic cell in an electromagnetic analysis based on the orthogonal FDTD (Finite-Difference Time-Domain) Algorithm. One of the numerical electromagnetic analyzing algorithms is the FDTD method based on Maxwell’s equation. The basic FDTD method divides the analyzed space into cubic cells and directly calculates the electrical and magnetic fields of the cells by discretizing the Maxwell’s equation of electromagnetic fields, where the derivatives with respect to time and space are replaced by a numerical difference. The development of computer performance brings about an actual execution of the FDTD method on a usual personal computer recently. In dealing with a diagonal and curved wire, the boundaries of which do not coincide with the finite-difference grid lines, the staircase approximation has been commonly used. However, the approximation causes the large error in a resonant frequency and a propagation time of a system including the diagonal or curved wire. The proposed method can express a diagonal and curved wires on a rectangular surface composing a cubic cell by transforming the general integral form of Maxwell’s equation to the different integral form around the wires. This proposed method is also useful to calculate surge propagation on an arbitrary three-dimensional skeleton structure including a diagonal or curved grid such as a tower model and so on.

  6. Volume localized spin echo correlation spectroscopy with suppression of 'diagonal' peaks.

    Science.gov (United States)

    Banerjee, Abhishek; Chandrakumar, N

    2014-02-01

    Two dimensional homonuclear (1)H correlation spectroscopy is of considerable interest for volume localized spectral studies, both in vivo and in vitro, of biological as well as material objects. The information principally sought from correlation spectra resides in the cross-peaks, which are often masked however by the presence of diagonal peaks in COSY, or 'pseudo-diagonal' peaks at F1=0 in SECSY. It has therefore been a concern to suppress these diagonal or 'pseudo-diagonal' peaks, in order to ensure that cross-peak information is fully discernible. We present here a report of our work on volume localized DIagonal Suppressed Spin Echo Correlation specTroscopy (LDISSECT) and demonstrate its performance in comparison to the standard volume localized SECSY experiment, employing brain metabolite phantoms in a gel. The sequence works in the inhomogeneous, multi-component environment by exploiting the short acquisition time to suppress undesired information by employing an additional rf pulse. A brief description of the pulse sequence, its theory, and simulations are also included, besides experimental benchmarking on two brain metabolite phantoms in gel phase.

  7. Sex determination in modern Greeks using diagonal measurements of molar teeth.

    Science.gov (United States)

    Zorba, Eleni; Moraitis, Konstantinos; Eliopoulos, Constantine; Spiliopoulou, Chara

    2012-04-10

    Sex determination is a necessary step in the investigation of unidentified human remains from a forensic context. Teeth, as one of the strongest tissues in the human body, can be used for this purpose. Most studies of sexual dimorphism in teeth are based on the traditional mesiodistal and buccolingual crown measurements. The purpose of this study is to examine the degree of sexual dimorphism in permanent molars of modern Greeks using crown and cervical diagonal diameters, and to evaluate their applicability in sex determination. A total of 344 permanent molars in 107 individuals (53 male and 54 female) from the Athens Collection were examined. Crown and cervical diagonal diameters of both maxillary and mandibular molars were measured. It was found that males have larger molars than females and in 19 out of 24 dimensions measured male molars exceeded female molars significantly (Pdiagonal diameters have found to be more sexually diamorphic than crown diagonal diameters. In discriminant function analysis the variables entered more frequently were the cervical diagonal diameters mainly of mandibular molars. Classification accuracy was found to be 93% for the total sample, 77.4% for upper jaw, and 88.4% for the lower jaw. Accuracy rates were higher for cervical than crown diagonal diameters. The data generated from the present study suggest that this metric method can be useful and reliable for sex determination, especially when the traditional dental measurements are not applicable.

  8. 三体Bell对角态的纠缠%Entanglement of Tripartite Bell Diagonal States

    Institute of Scientific and Technical Information of China (English)

    赵慧; 张兴华

    2011-01-01

    给出了三体2(×)2(×)3Bell对角态纠缠判定的一个必要条件和3(×)3(×)3Bell对角态纠缠的充分条件,进一步研究了3(×)3(×)3Bell对角态纠缠与密度矩阵部分转置的关系以及Bell对角态负性的数学表达式.%A necessary condition of entanglement for tripartite 2 (⊕)2 (⊕)3 Bell diagonal states and a sufficient condition of entanglement for 3 (⊕)3 (⊕)3 Bell diagonal states are presented. Moreover, the relation between entanglement of 3(⊕)3(⊕)3 Bell diagonal states and partial transpose of density matrix is investigated. And an analytical expression of negative for Bell diagonal states is presented.Key words: Bell diagonal states; entanglement; density matrix Robust Estimation for Varying Coefficient Model Abstract: This paper considers robust estimation of varying coefficient models with emphasis on resistance against outliers. By combining B-splines method with taut string method, a robust estimation procedure is proposed. Based on local quadratic approximation, an iterative algorithm is introduced. Simulation study indicates that the proposed method is robust.

  9. Medial branch neurotomy in low back pain

    Energy Technology Data Exchange (ETDEWEB)

    Masala, Salvatore; Mammucari, Matteo; Simonetti, Giovanni [Interventional Radiology and Radiotherapy University ' ' Tor Vergata' ' , Department of Diagnostic and Molecular Imaging, Rome (Italy); Nano, Giovanni [Interventional Radiology and Radiotherapy University ' ' Tor Vergata' ' , Department of Diagnostic and Molecular Imaging, Rome (Italy); University ' ' Tor Vergata' ' , Department of Radiology, Rome (Italy); Marcia, Stefano [S. Giovanni di Dio Hospital, Department of Diagnostic and Molecular Imaging, Cagliari (Italy)

    2012-07-15

    This study aimed to assess the effectiveness of pulsed radiofrequency medial branch dorsal ramus neurotomy in patients with facet joint syndrome. From January 2008 to April 2010, 92 patients with facet joint syndrome diagnosed by strict inclusion criteria and controlled diagnostic blocks undergone medial branch neurotomy. We did not exclude patients with failed back surgery syndrome (FBSS). Electrodes (20G) with 5-mm active tip were placed under fluoroscopy guide parallel to medial branch. Patients were followed up by physical examination and by Visual Analog Scale and Oswestry Disability Index at 1, 6, and 12 months. In all cases, pain improvement was statistically significant and so quality of life. Three non-FBSS patients had to undergo a second neurotomy because of non-satisfactory pain decrease. Complications were reported in no case. Medial branch radiofrequency neurotomy has confirmed its well-established effectiveness in pain and quality of life improvement as long as strict inclusion criteria be fulfilled and nerve ablation be accomplished by parallel electrode positioning. This statement can be extended also to FBSS patients. (orig.)

  10. Hierarchical error representation in medial prefrontal cortex.

    Science.gov (United States)

    Zarr, Noah; Brown, Joshua W

    2016-01-01

    The medial prefrontal cortex (mPFC) is reliably activated by both performance and prediction errors. Error signals have typically been treated as a scalar, and it is unknown to what extent multiple error signals may co-exist within mPFC. Previous studies have shown that lateral frontal cortex (LFC) is arranged in a hierarchy of abstraction, such that more abstract concepts and rules are represented in more anterior cortical regions. Given the close interaction between lateral and medial prefrontal cortex, we explored the hypothesis that mPFC would be organized along a similar rostro-caudal gradient of abstraction, such that more abstract prediction errors are represented further anterior and more concrete errors further posterior. We show that multiple prediction error signals can be found in mPFC, and furthermore, these are arranged in a rostro-caudal gradient of abstraction which parallels that found in LFC. We used a task that requires a three-level hierarchy of rules to be followed, in which the rules changed without warning at each level of the hierarchy. Task feedback indicated which level of the rule hierarchy changed and led to corresponding prediction error signals in mPFC. Moreover, each identified region of mPFC was preferentially functionally connected to correspondingly anterior regions of LFC. These results suggest the presence of a parallel structure between lateral and medial prefrontal cortex, with the medial regions monitoring and evaluating performance based on rules maintained in the corresponding lateral regions.

  11. [Arthritis of the Medial Knee Joint Compartment].

    Science.gov (United States)

    Matziolis, G; Röhner, E

    2015-10-01

    23 % of all persons older than 65 years suffer from osteoarthritis of the medial compartment of the knee joint, a very common situation in orthopaedic practice 1. As a result of the demographic trend the number of patients is expected to increase in the future. Based on specific joint biomechanics and kinematics the medial knee joint compartment is more frequently affected than the lateral. Only an understanding of the functional anatomy and underlying pathology allows a critical evaluation of different available conservative and operative treatment options. This article gives an overview of diagnostic and therapeutic strategies of osteoarthritis of the medial knee joint. Frequently performed surgeries, e.g. high tibial osteotomy (HTO), unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) will be presented in a comparative manner. The actual scientific evidence will be given with the goal of an evidence based therapy that is adopted to stage and pathology of osteoarthritis of the medial compartment of the knee joint. Georg Thieme Verlag KG Stuttgart · New York.

  12. Rheo: Japanese Sound Art Interrogating Digital Mediality

    DEFF Research Database (Denmark)

    Vandsø, Anette

    2014-01-01

    THe article asks in what way the Japanese sound artist Ryoichi Kurokawa's audiovisual installation Rheo 5 Horisonz (2010) is 'digital'. Using Professor Lars Elleströms concept of 'mediality, the main claim in this article is that Rheo no only uses digital tehcnology, but also interrogates digital...

  13. Absent cavum septum pellucidum: a review with emphasis on associated commissural abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    Sundarakumar, Dinesh K.; Farley, Sarah A.; Nixon, Jason N. [Seattle Children' s Hospital, Department of Radiology, Seattle, WA (United States); Smith, Crysela M. [The University of Texas Health Science Center at San Antonio, Department of Radiology, San Antonio, TX (United States); Maravilla, Kenneth R.; Dighe, Manjiri K. [University of Washington, Department of Radiology, Seattle, WA (United States)

    2015-07-15

    The cavum septum pellucidum (CSP) is an important fetal midline forebrain landmark, and its absence often signifies additional underlying malformations. Frequently detected by prenatal sonography, absence of the CSP requires further imaging with pre- or postnatal MRI to characterize the accompanying abnormalities. This article reviews the developmental anatomy of the CSP and the pivotal role of commissurization in normal development. An understanding of the patterns of commissural abnormalities associated with absence of the CSP can lead to improved characterization of the underlying spectrum of pathology. (orig.)

  14. LAS NEURONAS DEL SEPTUM LATERAL MODIFICAN LA ACTIVIDAD DE LAS NEURONAS DEL NUCLEO TUBEROMAMILAR DEL HIPOTALAMO

    OpenAIRE

    2012-01-01

    El septum lateral (SL), es un núcleo del cerebro anterior, que, procesa la información sensorial afectiva procedente del hipocampo y dirige sus respuestas, importantes para la supervivencia, hacia las zonas del hipotálamo importantes para la motivación, como lo es el núcleo tuberomamilar del hipotálamo (TMN). El TMN contiene las neuronas histaminérgicas en el cerebro, la cual relacionamos con la vigilia y alerta en conductas motivadas y así puede dirigir y reforzar el comportamiento. El TM...

  15. Lipomatous Hypertrophy of the Interatrial Septum due to Long Term Steroid Use in Multiple Sclerosis Patient

    Directory of Open Access Journals (Sweden)

    Mustafa Bulut

    2013-08-01

    Full Text Available A 34-year-old woman with no cardiovascular history was referred to the cardiology clinic for palpitations. She was diagnosed as multiple sclerosis two years prior to current presentation and on long term both intravenous and oral prednisone therapy due to uncontrolled multiple sclerosis attacks. Transthoracic and transesophageal echocardiography showed a highly echogenic bilobed interatrial mass suggestive of fatty tissue. Multidetector cardiac tomography and cardiac magnetic resonance imaging confirmed mass to be lipomatous hypertrophy of the interatrial septum typically not spreading to the foramen ovale.

  16. Ruptura del septum ventricular como complicación de un evento coronario agudo

    OpenAIRE

    William J. Morales-Camacho; José M. Chilatra-Fonseca; Jessica E. Plata-Ortiz; Yisela P. Gómez-Mancilla; Andrea N. Villabona-Suárez; Sergio A. Villabona-Rosales

    2017-01-01

    La ruptura del septum ventricular (RSV) es una complicación mecánica infrecuente del infarto agudo de miocardio (IAM). Los principales factores de riesgo descritos son la edad avanzada, el género femenino, un primer episodio de IAM y la presencia de enfermedad coronaria. Se sospecha de esta patología cuando clínicamente se evidencia un deterioro inexplicable del estado hemodinámico posterior al infarto. Los estudios imagenológicos (ecocardiograma y Doppler color) ayudan a confirmar el diagnós...

  17. INVESTIGATION OF THE EFFECTS OF DIFFERENT EDGE JOINT ELEMENTS ON DIAGONAL TENSILE STRENGTH IN FURNITURE EDGE JOINTS

    Directory of Open Access Journals (Sweden)

    Arif GÜRAY

    2002-01-01

    Full Text Available In this work, the diagonal tensile strength of furniture edge joints such as wooden dowel, minifix, and alyan screw was investigated in panel-constructed boards for Suntalam and MDF Lam. For this purpose, a diagonal tensile strength test was applied to the 72 samples. According to the results, the maximum diagonal tensile strength was found to be in MDF Lam boards that jointed with alyan screw.

  18. Covariant Renormalizable Anisotropic Theories and Off-Diagonal Einstein-Yang-Mills-Higgs Solutions

    CERN Document Server

    Vacaru, Sergiu I

    2011-01-01

    We use an important decoupling property of gravitational field equations in the general relativity theory and modifications, written with respect to nonholonomic frames with 2+2 spacetime decomposition. This allows us to integrate the Einstein equations in very general forms with generic off--diagonal metrics depending on all spacetime coordinates via generating and integration functions containing (broken and un-broken) symmetry parameters. We associate families of off-diagonal Einstein manifolds to certain classes of covariant gravity theories which have a nice ultraviolet behavior and seem to be (super) renormalizable in a sense of covariant modifications of Ho\\v{r}ava-Lifshits gravity. The apparent breaking of Lorentz invariance is present in some "partner" anisotropically induced theories due to nonlinear coupling with effective parametric interactions determined by nonholonomic constraints and generic off-diagonal gravitational and matter fields configurations. Finally, we show how the constructions can...

  19. Wrapping corrections for non-diagonal boundaries in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Bajnok, Zoltán [MTA Lendület Holographic QFT Group, Wigner Research Centre,H-1525 Budapest 114, P.O.B. 49 (Hungary); Nepomechie, Rafael I. [Physics Department, P.O. Box 248046, University of Miami,Coral Gables, FL 33124 (United States)

    2016-02-03

    We consider an open string stretched between a Y=0 brane and a Y{sub θ}=0 brane. The latter brane is rotated with respect to the former by an angle θ, and is described by a non-diagonal boundary S-matrix. This system interpolates smoothly between the Y−Y (θ=0) and the Y−Ȳ (θ=π/2) systems, which are described by diagonal boundary S-matrices. We use integrability to compute the energies of one-particle states at weak coupling up to leading wrapping order (4, 6 loops) as a function of the angle. The results for the diagonal cases exactly match with those obtained previously.

  20. Shrinkage-based diagonal discriminant analysis and its applications in high-dimensional data.

    Science.gov (United States)

    Pang, Herbert; Tong, Tiejun; Zhao, Hongyu

    2009-12-01

    High-dimensional data such as microarrays have brought us new statistical challenges. For example, using a large number of genes to classify samples based on a small number of microarrays remains a difficult problem. Diagonal discriminant analysis, support vector machines, and k-nearest neighbor have been suggested as among the best methods for small sample size situations, but none was found to be superior to others. In this article, we propose an improved diagonal discriminant approach through shrinkage and regularization of the variances. The performance of our new approach along with the existing methods is studied through simulations and applications to real data. These studies show that the proposed shrinkage-based and regularization diagonal discriminant methods have lower misclassification rates than existing methods in many cases.

  1. Working memory and individual differences in the encoding of vertical, horizontal and diagonal symmetry.

    Science.gov (United States)

    Rossi-Arnaud, Clelia; Pieroni, Laura; Spataro, Pietro; Baddeley, Alan

    2012-09-01

    Previous studies, using a modified version of the sequential Corsi block task to examine the impact of symmetry on visuospatial memory, showed an advantage of vertical symmetry over non-symmetrical sequences, but no effect of horizontal or diagonal symmetry. The present four experiments investigated the mechanisms underlying the encoding of vertical, horizontal and diagonal configurations using simultaneous presentation and a dual-task paradigm. Results indicated that the recall of vertically symmetric arrays was always better than that of all other patterns and was not influenced by any of the concurrent tasks. Performance with horizontally or diagonally symmetrical patterns differed, with high performing participants showing little effect of concurrent tasks, while low performers were disrupted by concurrent visuospatial and executive tasks. A verbal interference had no effect on either group. Implications for processes involved in the encoding of symmetry are discussed, together with the crucial importance of individual differences.

  2. Diagonal reverse-phase chromatography applications in peptide-centric proteomics: ahead of catalogue-omics?

    Science.gov (United States)

    Gevaert, Kris; Van Damme, Petra; Martens, Lennart; Vandekerckhove, Joël

    2005-10-01

    Diagonal electrophoresis/chromatography was described 40 years ago and was used to isolate specific sets of peptides from simple peptide mixtures such as protease digests of purified proteins. Recently, we have adapted the core technology of diagonal chromatography so that the technique can be used in so-called gel-free, peptide-centric proteome studies. Here we review the different procedures we have developed over the past few years, sorting of methionyl, cysteinyl, amino terminal, and phosphorylated peptides. We illustrate the power of the technique, termed COFRADIC (combined fractional diagonal chromatography), in the case of a peptide-centric analysis of a sputum sol phase sample of a patient suffering from chronic obstructive pulmonary disease (COPD). We were able to identify an unexpectedly high number of intracellular proteins next to known biomarkers.

  3. Hyperglycemia decreased medial amygdala projections to medial preoptic area in experimental model of Diabetes Mellitus.

    OpenAIRE

    Yousef Mohamadi; Seyed Behnam-edin Jameie; Mohammad Akbari; Masumeh Staji; Fatemeh Moradi; Tahmineh Mokhtari; Maryam Khanehzad; Gholamreza Hassanzadeh

    2015-01-01

    In Wistar rats, reproductive behavior is controlled in a neural circuit of ventral forebrain including the medial amygdala (Me), bed nucleus of the stria terminalis (BNST) and medial preoptic area (MPOA) via perception of social odors. Diabetes Mellitus (DM) is a widespread metabolic disease that affects many organs in a variety of levels. DM can cause central neuropathies such as neuronal apoptosis, dendritic atrophy, neurochemical alterations and also causes reproductive dysfunctions. So we...

  4. Exact solution of the trigonometric SU(3) spin chain with generic off-diagonal boundary reflections

    Science.gov (United States)

    Li, Guang-Liang; Cao, Junpeng; Hao, Kun; Wen, Fakai; Yang, Wen-Li; Shi, Kangjie

    2016-09-01

    The nested off-diagonal Bethe ansatz is generalized to study the quantum spin chain associated with the SUq (3)R-matrix and generic integrable non-diagonal boundary conditions. By using the fusion technique, certain closed operator identities among the fused transfer matrices at the inhomogeneous points are derived. The corresponding asymptotic behaviors of the transfer matrices and their values at some special points are given in detail. Based on the functional analysis, a nested inhomogeneous T-Q relations and Bethe ansatz equations of the system are obtained. These results can be naturally generalized to cases related to the SUq (n) algebra.

  5. Exact solution of the trigonometric SU(3) spin chain with generic off-diagonal boundary reflections

    CERN Document Server

    Li, Guang-Liang; Hao, Kun; Yang, Wen-Li; Shi, Kangjie

    2016-01-01

    The nested off-diagonal Bethe Ansatz is generalized to study the quantum spin chain associated with the $SU_q(3)$ R-matrix and generic integrable non-diagonal boundary conditions. By using the fusion technique, certain closed operator identities among the fused transfer matrices at the inhomogeneous points are derived. The corresponding asymptotic behaviors of the transfer matrices and their values at some special points are given in detail. Based on the functional analysis, a nested inhomogeneous T-Q relations and Bethe Ansatz equations of the system are obtained. These results can be naturally generalized to cases related to the $SU_q(n)$ algebra.

  6. Exact solution of the trigonometric SU(3 spin chain with generic off-diagonal boundary reflections

    Directory of Open Access Journals (Sweden)

    Guang-Liang Li

    2016-09-01

    Full Text Available The nested off-diagonal Bethe ansatz is generalized to study the quantum spin chain associated with the SUq(3 R-matrix and generic integrable non-diagonal boundary conditions. By using the fusion technique, certain closed operator identities among the fused transfer matrices at the inhomogeneous points are derived. The corresponding asymptotic behaviors of the transfer matrices and their values at some special points are given in detail. Based on the functional analysis, a nested inhomogeneous T–Q relations and Bethe ansatz equations of the system are obtained. These results can be naturally generalized to cases related to the SUq(n algebra.

  7. Boundary energy of the open XXX chain with a non-diagonal boundary term

    Science.gov (United States)

    Nepomechie, Rafael I.; Wang, Chunguang

    2014-01-01

    We analyze the ground state of the open spin-1/2 isotropic quantum spin chain with a non-diagonal boundary term using a recently proposed Bethe ansatz solution. As the coefficient of the non-diagonal boundary term tends to zero, the Bethe roots split evenly into two sets: those that remain finite, and those that become infinite. We argue that the former satisfy conventional Bethe equations, while the latter satisfy a generalization of the Richardson-Gaudin equations. We derive an expression for the leading correction to the boundary energy in terms of the boundary parameters.

  8. Boundary energy of the open XXX chain with a non-diagonal boundary term

    CERN Document Server

    Nepomechie, Rafael I

    2013-01-01

    We analyze the ground state of the open spin-1/2 isotropic quantum spin chain with a non-diagonal boundary term using a recently proposed Bethe ansatz solution. As the coefficient of the non-diagonal boundary term tends to zero, the Bethe roots split evenly into two sets: those that remain finite, and those that become infinite. We argue that the former satisfy conventional Bethe equations, while the latter satisfy a generalization of the Richardson-Gaudin equations. We derive an expression for the leading correction to the boundary energy in terms of the boundary parameters.

  9. Algebraic techniques for diagonalization of a split quaternion matrix in split quaternionic mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Tongsong, E-mail: jiangtongsong@sina.com [Department of Mathematics, Linyi University, Linyi, Shandong 276005 (China); Department of Mathematics, Heze University, Heze, Shandong 274015 (China); Jiang, Ziwu; Zhang, Zhaozhong [Department of Mathematics, Linyi University, Linyi, Shandong 276005 (China)

    2015-08-15

    In the study of the relation between complexified classical and non-Hermitian quantum mechanics, physicists found that there are links to quaternionic and split quaternionic mechanics, and this leads to the possibility of employing algebraic techniques of split quaternions to tackle some problems in complexified classical and quantum mechanics. This paper, by means of real representation of a split quaternion matrix, studies the problem of diagonalization of a split quaternion matrix and gives algebraic techniques for diagonalization of split quaternion matrices in split quaternionic mechanics.

  10. Time-dependent renormalized Redfield theory II for off-diagonal transition in reduced density matrix

    Science.gov (United States)

    Kimura, Akihiro

    2016-09-01

    In our previous letter (Kimura, 2016), we constructed time-dependent renormalized Redfield theory (TRRT) only for diagonal transition in a reduced density matrix. In this letter, we formulate the general expression for off-diagonal transition in the reduced density matrix. We discuss the applicability of TRRT by numerically comparing the dependencies on the energy gap of the exciton relaxation rate by using the TRRT and the modified Redfield theory (MRT). In particular, we roughly show that TRRT improves MRT for the detailed balance about the excitation energy transfer reaction.

  11. Single-Channel Noise Reduction using Unified Joint Diagonalization and Optimal Filtering

    DEFF Research Database (Denmark)

    Nørholm, Sidsel Marie; Benesty, Jacob; Jensen, Jesper Rindom;

    2014-01-01

    In this paper, the important problem of single-channel noise reduction is treated from a new perspective. The problem is posed as a filtering problem based on joint diagonalization of the covariance matrices of the desired and noise signals. More specifically, the eigenvectors from the joint...... diagonalization corresponding to the least significant eigenvalues are used to form a filter, which effectively estimates the noise when applied to the observed signal. This estimate is then subtracted from the observed signal to form an estimate of the desired signal, i.e., the speech signal. In doing this, we...

  12. On the Reduction of a Complex Matrix to Triangular or Diagonal by Consimilarity

    Institute of Scientific and Technical Information of China (English)

    Tongsong Jiang; Musheng Wei

    2006-01-01

    Two n × n complex matrices A and B are said to be consimilar if S-1 AS = B for some nonsingular n × n complex matrix S. This paper, by means of real representation of a complex matrix, studies problems of reducing a given n × n complex matrix A to triangular or diagonal form by consimilarity, not only gives necessary and sufficient conditions for contriangularization and condiagonalization of a complex matrix, but also derives an algebraic technique of reducing a matrix to triangular or diagonal form by consimilarity.

  13. On the Marginal Distribution of the Diagonal Blocks in a Blocked Wishart Random Matrix

    Directory of Open Access Journals (Sweden)

    Kjetil B. Halvorsen

    2016-01-01

    Full Text Available Let A be a (m1+m2×(m1+m2 blocked Wishart random matrix with diagonal blocks of orders m1×m1 and m2×m2. The goal of the paper is to find the exact marginal distribution of the two diagonal blocks of A. We find an expression for this marginal density involving the matrix-variate generalized hypergeometric function. We became interested in this problem because of an application in spatial interpolation of random fields of positive definite matrices, where this result will be used for parameter estimation, using composite likelihood methods.

  14. Bias-corrected diagonal discriminant rules for high-dimensional classification.

    Science.gov (United States)

    Huang, Song; Tong, Tiejun; Zhao, Hongyu

    2010-12-01

    Diagonal discriminant rules have been successfully used for high-dimensional classification problems, but suffer from the serious drawback of biased discriminant scores. In this article, we propose improved diagonal discriminant rules with bias-corrected discriminant scores for high-dimensional classification. We show that the proposed discriminant scores dominate the standard ones under the quadratic loss function. Analytical results on why the bias-corrected rules can potentially improve the predication accuracy are also provided. Finally, we demonstrate the improvement of the proposed rules over the original ones through extensive simulation studies and real case studies.

  15. Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex

    Directory of Open Access Journals (Sweden)

    Tariq Waseem Chohan

    2014-09-01

    Full Text Available Schizophrenia is thought to arise due to a complex interaction between genetic and environmental factors during early neurodevelopment. We have recently shown that partial genetic deletion of the schizophrenia susceptibility gene neuregulin 1 (Nrg1 and adolescent stress interact to disturb sensorimotor gating, neuroendocrine activity and dendritic morphology in mice. Both stress and Nrg1 may have converging effects upon N-methyl-D-aspartate receptors (NMDARs which are implicated in the pathogenesis of schizophrenia, sensorimotor gating and dendritic spine plasticity. Using an identical repeated restraint stress paradigm to our previous study, here we determined NMDAR binding across various brain regions in adolescent Nrg1 heterozygous (HET and wild-type (WT mice using [3H] MK-801 autoradiography. Repeated restraint stress increased NMDAR binding in the ventral part of the lateral septum (LSV and the dentate gyrus (DG of the hippocampus irrespective of genotype. Partial genetic deletion of Nrg1 interacted with adolescent stress to promote an altered pattern of NMDAR binding in the infralimbic (IL subregion of the medial prefrontal cortex. In the IL, whilst stress tended to increase NMDAR binding in WT mice, it decreased binding in Nrg1 HET mice. However in the DG, stress selectively increased the expression of NMDAR binding in Nrg1 HET mice but not WT mice. These results demonstrate a Nrg1-stress interaction during adolescence on NMDAR binding in the medial prefrontal cortex.

  16. Interaction of a vasopressin antagonist with vasopressin receptors in the septum of the rat brain

    Energy Technology Data Exchange (ETDEWEB)

    Dorsa, D.M.; Brot, M.D.; Shewey, L.M.; Meyers, K.M.; Szot, P.; Miller, M.A.

    1988-01-01

    The ability of d(CH2)5-Tyr(Me)-arginine-8-vasopressin, an antagonist of peripheral pressoric (V1-type) vasopressin receptors, to label vasopressin binding sites in the septum of the rat brain was evaluated. Using crude membrane preparations from the septum, /sup 3/H-arginine-8-vasopressin (AVP) specifically labels a single class of binding sites with a Kd of 2.9 nM and maximum binding site concentration of 19.8 fmole/mg protein. /sup 3/H-Antag also labels a single class of membrane sites but with higher affinity (Kd = 0.47 nM) and lower capacity (10.1 fmole/mg protein) than /sup 3/H-AVP. The rank order of potency of various competitor peptides for /sup 3/H-AVP and /sup 3/H-Antag binding was similar. Oxytocin was 100-1,000 fold less potent than AVP in competing for binding with both ligands. /sup 3/H-AVP and /sup 3/H-Antag showed similar labeling patterns when incubated with septal tissue slices. Unlabeled Antag also effectively antagonized vasopressin-stimulated phosphatidylinositol hydrolysis in septal tissue slices.

  17. Septum magnet MNP-23 for the CERN PS experimental area and its fast interlock system

    CERN Document Server

    Borburgh, J; Prost, A; Zickler, T

    2004-01-01

    Two MNP-23 septum-like magnets are installed at CERN in the transfer line from the Proton Synchrotron (PS) to the East Hall Experimental Area. They are exposed to extremely high doses of ionizing radiation. In the past, the magnets experienced two catastrophic failures due to overheating of its coils and cannot be repaired. The magnets of improved design which is subject of this article are built as replacements for the magnets presently installed. The MNP-23 is a resistive C shaped iron-dominated magnet made of solid low carbon steel blocks. The excitation windings consist of two water-cooled coils wound from hollow copper conductor. The septum design of these magnets implies a high current density which requires an efficient water cooling system. The newly designed cooling circuit provides better cooling performance and more reliability. To avoid failures due to coil overheating, an elaborate interlock system was developed and installed. It consists of two parts: firstly a slow, more classic sensor, to dete...

  18. Nasal septum changes in adolescent patients treated with rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Tehnia Aziz

    2016-02-01

    Full Text Available Objective: To analyze cone-beam computed tomography (CBCT scans to measure changes in nasal septal deviation (NSD after rapid maxillary expansion (RME treatment in adolescent patients. Methods: This retrospective study involved 33 patients presenting with moderate to severe nasal septum deviation as an incidental finding. Out of these 33 patients, 26 were treated for transverse maxillary constriction with RME and seven, who did not undergo RME treatment, were included in the study as control group. CBCT scans were taken before appliance insertion and after appliance removal. These images were analyzed to measure changes in nasal septum deviation (NSD. Analysis of variance for repeated measures (ANOVA was used. Results: No significant changes were identified in NSD regardless of the application or not of RME treatment and irrespective of the baseline deviation degree. Conclusion: This study did not provide strong evidence to suggest that RME treatment has any effect on NSD in adolescent patients; however, the results should be interpreted with caution, due to the small sample size and large variation amongst individual patient characteristics.

  19. CyDiv, a conserved and novel filamentous Cyanobacteria cell division protein involved in septum localization.

    Directory of Open Access Journals (Sweden)

    Dinka eMandakovic

    2016-02-01

    Full Text Available Cell division in bacteria has been studied mostly in Escherichia coli and Bacillus subtilis, model organisms for Gram-negative and Gram-positive bacteria, respectively. However, cell division in filamentous cyanobacteria is poorly understood. Here, we identified a novel protein, named CyDiv (Cyanobacterial Division, encoded by the all2320 gene in Anabaena sp. PCC 7120. We show that CyDiv plays a key role during cell division. CyDiv has been previously described only as an exclusive and conserved hypothetical protein in filamentous cyanobacteria. Using polyclonal antibodies against CyDiv, we showed that it localizes at different positions depending on cell division timing: poles, septum, in both daughter cells, but also in only one of the daughter cells. The partial deletion of CyDiv gene generates partial defects in cell division, including severe membrane instability and anomalous septum localization during late division. The inability to complete knock out CyDiv strains suggests that it is an essential gene. In silico structural protein analyses and our experimental results suggest that CyDiv is an FtsB/DivIC-like protein, and could therefore, be part of an essential late divisome complex in Anabaena sp. PCC 7120.

  20. [One case of huge cyst at the back end of nasal septum].

    Science.gov (United States)

    Zang, Jian; Liu, Qian; Jiang, Xuejun

    2014-04-01

    A male of 17 years old complained of bilateral nasal congestion with mouth breathing for half a year. The physical examination showed patency of bilateral nasal cavity. Nasopharyngeal fiberscope revealed a huge spherical smooth reddish mass at the nasopharyngeal posterior wall and the back-end of nasal cavity blocking the entire postnaris and contacting with bilateral tubal tori, the size of which is about 3.5 cm x 2.5 cm. The nasopharyngeal 3D-CT showed a low density cystic mass area in the nasopharynx with smooth edges, and the CT value is approximately 32.4 HU. No exact enhancement was observed. The cystic mass originated from and compressed the back end of nasal septum. A semicircular defect in the leading edge of clivus was observed, and the inferior wall of sphenoid sinus is compressed uplifted upwards. The nasopharyngeal MR showed that the nasopharyngeal lesion presented short T1 and long T2 signals with multiple small wall nodules around. Neither the lesion nor the peripheral nodules can be significantly enhanced by enhancement scan. After a nasal endoscopic surgery, the case was definitely diagnosed as nasal septum back-end huge cyst.

  1. Septate uterus with cervical duplication and a longitudinal vaginal septum: an unclassified mullerian anomaly

    Directory of Open Access Journals (Sweden)

    Ruchika Mangla

    2016-02-01

    Full Text Available Uterine anomalies are the result of disturbances in the development, formation or fusion of the mullerian ducts during foetal life with an incidence of 0.001%-10% in general population. These patients most often present with amenorrhoea, dysmenorrhoea, dyspareunia and infertility. Women with these anomalies are more prone to poor foetal outcomes such as first trimester losses or preterm labour. We report a case of a 35 years old female with septate uterus with cervical duplication and a longitudinal vaginal septum. Diagnosis was obtained by physical examination, ultrasound imaging, hysterosalphingography and magnetic resonance imaging and hysterolaproscopy. The clinical presentation of such a case and surgical options available were studied, and the excision of the vaginal septum was done. This case of congenital uterine anomaly does not fit into the current classification system of mullerian anomalies by American fertility society, which is based on the traditional caudal to cranial, unidirectional developmental pattern. This strongly indicates the possibility of an alternative mechanism of mullerian development. [Int J Reprod Contracept Obstet Gynecol 2016; 5(2.000: 536-538

  2. CyDiv, a Conserved and Novel Filamentous Cyanobacterial Cell Division Protein Involved in Septum Localization

    Science.gov (United States)

    Mandakovic, Dinka; Trigo, Carla; Andrade, Derly; Riquelme, Brenda; Gómez-Lillo, Gabriela; Soto-Liebe, Katia; Díez, Beatriz; Vásquez, Mónica

    2016-01-01

    Cell division in bacteria has been studied mostly in Escherichia coli and Bacillus subtilis, model organisms for Gram-negative and Gram-positive bacteria, respectively. However, cell division in filamentous cyanobacteria is poorly understood. Here, we identified a novel protein, named CyDiv (Cyanobacterial Division), encoded by the all2320 gene in Anabaena sp. PCC 7120. We show that CyDiv plays a key role during cell division. CyDiv has been previously described only as an exclusive and conserved hypothetical protein in filamentous cyanobacteria. Using polyclonal antibodies against CyDiv, we showed that it localizes at different positions depending on cell division timing: poles, septum, in both daughter cells, but also in only one of the daughter cells. The partial deletion of CyDiv gene generates partial defects in cell division, including severe membrane instability and anomalous septum localization during late division. The inability to complete knock out CyDiv strains suggests that it is an essential gene. In silico structural protein analyses and our experimental results suggest that CyDiv is an FtsB/DivIC-like protein, and could therefore, be part of an essential late divisome complex in Anabaena sp. PCC 7120. PMID:26903973

  3. Bilateral fungiform papilloma with synchronous verrucous carcinoma of the nasal septum: a rare presentation and a literature review.

    Science.gov (United States)

    Maithani, T; Dey, D; Pandey, A; Chawla, N

    2012-04-01

    Fungiform papillomas are benign mucosal neoplasms presenting as a unilateral exophytic mass involving the anterior portion of the nasal septum. In this study, we present an exceptional case of a bilateral fungiform papilloma with a synchronous verrucous carcinoma of the nasal septum. A case study with a review of the literature concerning malignant changes in fungiform papilloma. The general consensus in most of the literature is that malignant change in fungiform papilloma is exceptional. Our patient is probably the third reported case of verrucous carcinoma of the nasal septum, and the first report of a bilateral fungiform papilloma with a synchronous verrucous carcinoma. The tumour was subjected to complete surgical removal in the first instance. There was no recurrence at follow up seven months after surgery. Although fungiform papillomas are generally not premalignant, occasional malignant transformation may occur. Thus, they must be managed with the utmost cautiousness.

  4. Foot medial longitudinal-arch deformation during quiet standing and gait in subjects with medial tibial stress syndrome

    DEFF Research Database (Denmark)

    Bandholm, Thomas Quaade; Boysen, Lisbeth; Haugaard, Stine

    2008-01-01

    ). There was no correlation between medial longitudinal-arch deformation during quiet standing and gait in either of the 2 groups (r .653). The subjects with medial tibial stress syndrome in this study demonstrated increased navicular drop and medial longitudinal-arch deformation during quiet standing......The objective of this study was to investigate (1) if subjects with medial tibial stress syndrome demonstrate increased navicular drop and medial longitudinal-arch deformation during quiet standing and gait compared with healthy subjects, and (2) the relationship between medial longitudinal......-arch deformation during quiet standing and gait. Thirty subjects aged 20 to 32 years were included (15 with medial tibial stress syndrome and 15 controls). Navicular drop and medial longitudinal-arch deformation were measured during quiet standing with neutral and loaded foot using a ruler and digital photography...

  5. Cholinergic Septo-Hippocampal Innervation Is Required for Trace Eyeblink Classical Conditioning

    Science.gov (United States)

    Fontan-Lozano, Angela; Troncoso, Julieta; Munera, Alejandro; Carrion, Angel Manuel; Delgado-Garcia, Jose Maria

    2005-01-01

    We studied the effects of a selective lesion in rats, with 192-IgG-saporin, of the cholinergic neurons located in the medial septum/diagonal band (MSDB) complex on the acquisition of classical and instrumental conditioning paradigms. The MSDB lesion induced a marked deficit in the acquisition, but not in the retrieval, of eyeblink classical…

  6. Cholinergic Septo-Hippocampal Innervation Is Required for Trace Eyeblink Classical Conditioning

    Science.gov (United States)

    Fontan-Lozano, Angela; Troncoso, Julieta; Munera, Alejandro; Carrion, Angel Manuel; Delgado-Garcia, Jose Maria

    2005-01-01

    We studied the effects of a selective lesion in rats, with 192-IgG-saporin, of the cholinergic neurons located in the medial septum/diagonal band (MSDB) complex on the acquisition of classical and instrumental conditioning paradigms. The MSDB lesion induced a marked deficit in the acquisition, but not in the retrieval, of eyeblink classical…

  7. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo

    NARCIS (Netherlands)

    Moor, E; de Boer, P; Westerink, B.H.C.

    1998-01-01

    In the present study, the regulation of acetylcholine release from the ventral hippocampus by gamma-aminobutyric acid (GABA) was investigated in vivo. GABA receptor agonists and antagonists were administered locally in the medial septum and the adjacent vertical limb of the diagonal band of Broca, o

  8. A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast

    Science.gov (United States)

    Sethi, Kriti; Palani, Saravanan; Cortés, Juan C. G.; Sato, Mamiko; Sevugan, Mayalagu; Ramos, Mariona; Vijaykumar, Shruthi; Osumi, Masako; Naqvi, Naweed I.; Ribas, Juan Carlos; Balasubramanian, Mohan

    2016-01-01

    Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring, whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is also coordinated with division septum assembly. How the actomyosin ring interacts with the plasma membrane and the plasma membrane-localized septum synthesizing machinery remains poorly understood. In Schizosaccharomyces pombe, an attractive model organism to study cytokinesis, the β-1,3-glucan synthase Cps1p / Bgs1p, an integral membrane protein, localizes to the plasma membrane overlying the actomyosin ring and is required for primary septum synthesis. Through a high-dosage suppressor screen we identified an essential gene, sbg1+ (suppressor of beta glucan synthase 1), which suppressed the colony formation defect of Bgs1-defective cps1-191 mutant at higher temperatures. Sbg1p, an integral membrane protein, localizes to the cell ends and to the division site. Sbg1p and Bgs1p physically interact and are dependent on each other to localize to the division site. Loss of Sbg1p results in an unstable actomyosin ring that unravels and slides, leading to an inability to deposit a single contiguous division septum and an important reduction of the β-1,3-glucan proportion in the cell wall, coincident with that observed in the cps1-191 mutant. Sbg1p shows genetic and / or physical interaction with Rga7p, Imp2p, Cdc15p, and Pxl1p, proteins known to be required for actomyosin ring integrity and efficient septum synthesis. This study establishes Sbg1p as a key member of a group of proteins that link the plasma membrane, the actomyosin ring, and the division septum assembly machinery in fission yeast. PMID:27749909

  9. Medial Cochlear Efferent Function: A Theoretical Analysis

    Science.gov (United States)

    Mountain, David C.

    2011-11-01

    Since the discovery of the cochlear efferent system, many hypotheses have been put forth for its function. These hypotheses for its function range from protecting the cochlea from over stimulation to improving the detection of sounds in noise. It is known that the medial efferent system innervates the outer hair cells and that stimulation of this system reduces basilar membrane and auditory nerve sensitivity which suggests that this system acts to decrease the gain of the cochlear amplifier. Here I present modeling results as well as analysis of published experimental data that suggest that the function of the medial efferent reflex is to decrease the cochlear amplifier gain by just the right amount so that the nonlinearity in the basilar membrane response lines up perfectly with the inner hair cell nonlinear transduction process to produce a hair cell receptor potential that is proportional to the logarithm of the sound pressure level.

  10. [SECOT consensus on medial femorotibial osteoarthritis].

    Science.gov (United States)

    Moreno, A; Silvestre, A; Carpintero, P

    2013-01-01

    A consensus, prepared by SECOT, is presented on the management of medial knee compartment osteoarthritis, in order to establish clinical criteria and recommendations directed at unifying the criteria in its management, dealing with the factors involved in the pathogenesis of medial femorotibial knee osteoarthritis, the usefulness of diagnostic imaging techniques, and the usefulness of arthroscopy. Conservative and surgical treatments are also analysed. The experts consulted showed a consensus (agreed or disagreed) in 65.8% of the items considered, leaving 14items where no consensus was found, which included the aetiopathogenesis of the osteoarthritis, the value of NMR in degenerative disease, the usefulness of COX-2 and the chondroprotective drugs, as well as on the ideal valgus tibial osteotomy technique. © 2013 SECOT. Published by Elsevier Espana. All rights reserved.

  11. Masseter and medial pterygoid muscle hypertrophy.

    Science.gov (United States)

    Guruprasad, R; Rishi, Sudhirkumar; Nair, Preeti P; Thomas, Shaji

    2011-09-26

    Hypertrophy refers to an enlargement caused by an increase in the size but not in the number of cells. Generalised masticatory muscle hypertrophy may affect the temporalis muscle, masseters and medial pterygoids in a variety of combinations. Masseteric hypertrophy may present as either unilateral or bilateral painless swelling of unknown origin in the region of angle of mandible. It is a relatively rare condition and presents a diagnostic dilemma. While the history and clinical examination are important in differentiating this benign condition from parotid or dental pathology, they cannot necessarily exclude rare malignant lesion within the muscle. Advanced imaging modalities like CT and MRI are essential to confirm the diagnosis. Here the authors are reporting a unique case of masseter muscle hypertrophy along with medial pterygoid hypertrophy which was missed clinically but confirmed using CT and MRI.

  12. Characterization of GABAergic neurons in the mouse lateral septum: a double fluorescence in situ hybridization and immunohistochemical study using tyramide signal amplification.

    Directory of Open Access Journals (Sweden)

    Changjiu Zhao

    Full Text Available Gamma-aminobutyric acid (GABA neurotransmission in the lateral septum (LS is implicated in modulating various behavioral processes, including emotional reactivity and maternal behavior. However, identifying the phenotype of GABAergic neurons in the CNS has been hampered by the longstanding inability to reliably detect somal immunoreactivity for GABA or glutamic acid decarboxylase (GAD, the enzyme that produces GABA. In this study, we designed unique probes for both GAD65 (GAD2 and GAD67 (GAD1, and used fluorescence in Situ hybridization (FISH with tyramide signal amplification (TSA to achieve unequivocal detection of cell bodies of GABAergic neurons by GAD mRNAs. We quantitatively characterized the expression and chemical phenotype of GABAergic neurons across each subdivision of LS and in cingulate cortex (Cg and medial preoptic area (MPOA in female mice. Across LS, almost all GAD65 mRNA-expressing neurons were found to contain GAD67 mRNA (approximately 95-98%, while a small proportion of GAD67 mRNA-containing neurons did not express GAD65 mRNA (5-14%. Using the neuronal marker NeuN, almost every neuron in LS (> 90% was also found to be GABA-positive. Interneuron markers using calcium-binding proteins showed that LS GABAergic neurons displayed immunoreactivity for calbindin (CB or calretinin (CR, but not parvalbumin (PV; almost all CB- or CR-immunoreactive neurons (98-100% were GABAergic. The proportion of GABAergic neurons immunoreactive for CB or CR varied depending on the subdivisions examined, with the highest percentage of colocalization in the caudal intermediate LS (LSI (approximately 58% for CB and 35% for CR. These findings suggest that the vast majority of GABAergic neurons within the LS have the potential for synthesizing GABA via the dual enzyme systems GAD65 and GAD67, and each subtype of GABAergic neurons identified by distinct calcium-binding proteins may exert unique roles in the physiological function and neuronal circuitry of

  13. Masseter and medial pterygoid muscle hypertrophy

    OpenAIRE

    R, Guruprasad; Rishi, Sudhirkumar; Nair, Preeti P; Thomas, Shaji

    2011-01-01

    Hypertrophy refers to an enlargement caused by an increase in the size but not in the number of cells. Generalised masticatory muscle hypertrophy may affect the temporalis muscle, masseters and medial pterygoids in a variety of combinations. Masseteric hypertrophy may present as either unilateral or bilateral painless swelling of unknown origin in the region of angle of mandible. It is a relatively rare condition and presents a diagnostic dilemma. While the history and clinical examination ar...

  14. Functional bundles of the medial patellofemoral ligament.

    Science.gov (United States)

    Kang, Hui Jun; Wang, Fei; Chen, Bai Cheng; Su, Yan Ling; Zhang, Zhan Chi; Yan, Chang Bao

    2010-11-01

    The purpose of this study was to explore the anatomy and evaluate the function of the medial patellofemoral ligament (MPFL). Anatomical dissection was performed on 12 fresh-frozen knee specimens. The MPFL is a condensation of capsular fibers, which originates at the medial femoral condyle. It runs transversely and inserts to the medial edge of the patella. With the landmark of the medial femur epicondyle (MFE), the femoral origination was located: just 8.90 ± 3.27 mm proximally and 13.47 ± 3.68 mm posteriorly to the MFE. The most interesting finding in present study was functional bundles of its patellar insertion. Approximately from the femoral origination point, fibers of the MPFL form two relatively concentrated fiber bundles: the inferior-straight bundle and the superior-oblique bundle. The whole length of each was 71.78 ± 5.51 and 73.67 ± 5.40 mm, respectively. The included angle between bundles was 15.1° ± 2.1°. Although the superior-oblique bundle and the inferior-straight bundle run on the patellar MPFL inferiorly and superiorly, respectively, as their name indicates, the two bundles are not entirely separated, which make MPFL one intact structure. The inferior-straight bundle is the main static soft tissue restraints where the superior-oblique bundle associated with vastus medialis obliquus (VMO) is to serve as the main dynamic soft tissue restraints. So this finding may provide the theoretical foundation for the anatomical reconstruction of the MPFL and shed lights on the future researchers.

  15. POLARONS IN THE 3-BAND PEIERLS-HUBBARD MODEL - AN EXACT DIAGONALIZATION STUDY

    NARCIS (Netherlands)

    DOBRY, A; GRECO, A; LORENZANA, J; RIERA, J

    1994-01-01

    We have studied the three-band Peierls-Hubbard model describing the Cu-O layers in high-T(c) superconductors by using Lanczos diagonalization and assuming infinite mass for the ions. When the system is doped with one hole, and for lambda (the electron-lattice coupling strength) greater than a critic

  16. Relation between Feynman cycles and off-diagonal long-range order.

    Science.gov (United States)

    Ueltschi, Daniel

    2006-10-27

    The usual order parameter for Bose-Einstein condensation involves the off-diagonal correlation function of Penrose and Onsager, but an alternative is Feynman's notion of infinite cycles. We present a formula that relates both order parameters. We discuss its validity with the help of rigorous results and heuristic arguments. The conclusion is that infinite cycles do not always represent the Bose condensate.

  17. Off-diagonal long-range order in generalized Hubbard models

    NARCIS (Netherlands)

    Michielsen, Kristel; Raedt, Hans De

    1997-01-01

    We present stochastic diagonalization results for the ground-state energy and the largest eigenvalue of the two-fermion density matrix of the BCS reduced Hamiltonian, the Hubbard model, and the Hubbard model with correlated hopping. The system-size dependence of this eigenvalue is used to study the

  18. Robust structural damage detection and localization based on joint approximate diagonalization technique in frequency domain

    Science.gov (United States)

    Cao, Shancheng; Ouyang, Huajiang

    2017-01-01

    The structural characteristic deflection shapes (CDS’s) such as mode shapes and operational deflection shapes are highly sensitive to structural damage in beam- or plate-type structures. Nevertheless, they are vulnerable to measurement noise and could result in unacceptable identification errors. In order to increase the accuracy and noise robustness of damage identification based on CDS’s using vibration responses of random excitation, joint approximate diagonalization (JAD) technique and gapped smoothing method (GSM) are combined to form a sensitive and robust damage index (DI), which can simultaneously detect the existence of damage and localize its position. In addition, it is possible to apply this approach to damage identification of structures under ambient excitation. First, JAD method which is an essential technique of blind source separation is investigated to simultaneously diagonalize a set of power spectral density matrices corresponding to frequencies near a certain natural frequency to estimate a joint unitary diagonalizer. The columns of this joint diagonalizer contain dominant CDS’s. With the identified dominant CDS’s around different natural frequencies, GSM is used to extract damage features and a robust damage identification index is then proposed. Numerical and experimental examples of beams with cracks are used to verify the validity and noise robustness of JAD based CDS estimation and the proposed DI. Furthermore, damage identification using dominant CDS’s estimated by JAD method is demonstrated to be more accurate and noise robust than by the commonly used singular value decomposition method.

  19. High-performance implementation of Chebyshev filter diagonalization for interior eigenvalue computations

    Science.gov (United States)

    Pieper, Andreas; Kreutzer, Moritz; Alvermann, Andreas; Galgon, Martin; Fehske, Holger; Hager, Georg; Lang, Bruno; Wellein, Gerhard

    2016-11-01

    We study Chebyshev filter diagonalization as a tool for the computation of many interior eigenvalues of very large sparse symmetric matrices. In this technique the subspace projection onto the target space of wanted eigenvectors is approximated with filter polynomials obtained from Chebyshev expansions of window functions. After the discussion of the conceptual foundations of Chebyshev filter diagonalization we analyze the impact of the choice of the damping kernel, search space size, and filter polynomial degree on the computational accuracy and effort, before we describe the necessary steps towards a parallel high-performance implementation. Because Chebyshev filter diagonalization avoids the need for matrix inversion it can deal with matrices and problem sizes that are presently not accessible with rational function methods based on direct or iterative linear solvers. To demonstrate the potential of Chebyshev filter diagonalization for large-scale problems of this kind we include as an example the computation of the 102 innermost eigenpairs of a topological insulator matrix with dimension 109 derived from quantum physics applications.

  20. Stability of matrices with sufficiently strong negative-dominant-diagonal submatrices

    NARCIS (Netherlands)

    Nieuwenhuis, H.J.; Schoonbeek, L.

    1997-01-01

    A well-known sufficient condition for stability of a system of linear first-order differential equations is that the matrix of the homogeneous dynamics has a negative dominant diagonal. However, this condition cannot be applied to systems of second-order differential equations. In this paper we intr

  1. The effects of pelvic diagonal movements and resistance on the lumbar multifidus

    Science.gov (United States)

    Lee, Ji-Yeon; Lee, Dong-Yeop; Hong, Ji-Heon; Yu, Jae-Ho; Kim, Jin Seop

    2017-01-01

    [Purpose] The purpose of this study was to compare the effects of pelvic diagonal movements, made with and without resistance, on the thickness of lumbar multifidus muscles. [Subjects and Methods] Participants in this study were healthy subjects who had no musculoskeletal disorders or lumbar-related pain. Participants were positioned on their side and instructed to lie with their hip flexor at 40 degrees. Ultrasonography was used for measurement, and the values of two calculations were averaged. [Results] The thickness of ipsilateral lumbar multifidus muscles showed a significant difference following the exercise of pelvic diagonal movements. The results of anterior elevation movements and posterior depression movements also demonstrated significant difference. There was no significant difference in lumbar multifidus muscles thickness between movements made with and without resistance. [Conclusion] These findings suggest that pelvic diagonal movements can be an effective method to promote muscular activation of the ipsilateral multifidus. Furthermore, researchers have concluded that resistance is not required during pelvic diagonal movements to selectively activate the core muscles. PMID:28356650

  2. Off-diagonal Yukawa Couplings in the s-channel Charged Higgs Production at LHC

    CERN Document Server

    Hashemi, Majid

    2015-01-01

    The search for the heavy charged Higgs (mH+ > mtop) has been mainly based on the o?ff-shell top pair production process. However, resonance production in s-channel single top events is an important channel to search for this particle. In a previous work, it was shown that this process, i.e., qq' -> H+ -> tb + h.c., can lead to comparable results to what is already obtained from LHC searches through gb -> tH- process. What was obtained was, however, based on diagonal Yukawa couplings between incoming quarks assuming cs as the main incoming pair due to the CKM matrix element being close to unity. The aim of this paper is to show that off-diagonal couplings, like cb, may lead to substantial contributions to the cross section, even if the corresponding CKM matrix element is two orders of magnitude smaller. For this reason, the cross section is calculated for each initial state including all diagonal and off-diagonal terms, and all is finally added together to get the total cross section which is observed to be ~ ...

  3. Total correlations of the diagonal ensemble as a generic indicator for ergodicity breaking in quantum systems

    Science.gov (United States)

    Pietracaprina, F.; Gogolin, C.; Goold, J.

    2017-03-01

    The diagonal ensemble is the infinite time average of a quantum state following unitary dynamics in systems without degeneracies. In analogy to the time average of a classical phase-space dynamics, it is intimately related to the ergodic properties of the quantum system giving information on the spreading of the initial state in the eigenstates of the Hamiltonian. In this work we apply a concept from quantum information, known as total correlations, to the diagonal ensemble. Forming an upper bound on the multipartite entanglement, it quantifies the combination of both classical and quantum correlations in a mixed state. We generalize the total correlations of the diagonal ensemble to more general α -Renyi entropies and focus on the cases α =1 and α =2 with further numerical extensions in mind. Here we show that the total correlations of the diagonal ensemble is a generic indicator of ergodicity breaking, displaying a subextensive behavior when the system is ergodic. We demonstrate this by investigating its scaling in a range of spin chain models focusing not only on the cases of integrability breaking but also emphasize its role in understanding the transition from an ergodic to a many-body localized phase in systems with disorder or quasiperiodicity.

  4. Teaching the "Diagonalization Concept" in Linear Algebra with Technology: A Case Study at Galatasaray University

    Science.gov (United States)

    Yildiz Ulus, Aysegul

    2013-01-01

    This paper examines experimental and algorithmic contributions of advanced calculators (graphing and computer algebra system, CAS) in teaching the concept of "diagonalization," one of the key topics in Linear Algebra courses taught at the undergraduate level. Specifically, the proposed hypothesis of this study is to assess the effective…

  5. Congestion Control for ATM Networks Based on Diagonal Recurrent Neural Networks

    Institute of Scientific and Technical Information of China (English)

    HuangYunxian; YanWei

    1997-01-01

    An adaptive control model and its algorithms based on simple diagonal recurrent neural networks are presented for the dynamic congestion control in broadband ATM networks.Two simple dynamic queuing models of real networks are used to test the performance of the suggested control scheme.

  6. Investigation of Diagonal Antenna-Chassis Mode in Mobile Terminal LTE MIMO Antennas for Bandwidth Enhancement

    DEFF Research Database (Denmark)

    Zhang, Shuai; Zhao, Kun; Ying, Zhinong

    2015-01-01

    A diagonal antenna-chassis mode is investigated in long-term evolution multiple-input-multiple-output (LTE MIMO) antennas. The MIMO bandwidth is defined in this paper as the overlap range of the low-envelope correlation coefficient, high total efficiency, and -6-dB impedance matching bandwidths...

  7. Off-diagonal ekpyrotic scenarios and equivalence of modified, massive and/or Einstein gravity

    Directory of Open Access Journals (Sweden)

    Sergiu I. Vacaru

    2016-01-01

    Full Text Available Using our anholonomic frame deformation method, we show how generic off-diagonal cosmological solutions depending, in general, on all spacetime coordinates and undergoing a phase of ultra-slow contraction can be constructed in massive gravity. In this paper, there are found and studied new classes of locally anisotropic and (inhomogeneous cosmological metrics with open and closed spatial geometries. The late time acceleration is present due to effective cosmological terms induced by nonlinear off-diagonal interactions and graviton mass. The off-diagonal cosmological metrics and related Stückelberg fields are constructed in explicit form up to nonholonomic frame transforms of the Friedmann–Lamaître–Robertson–Walker (FLRW coordinates. We show that the solutions include matter, graviton mass and other effective sources modeling nonlinear gravitational and matter fields interactions in modified and/or massive gravity, with polarization of physical constants and deformations of metrics, which may explain certain dark energy and dark matter effects. There are stated and analyzed the conditions when such configurations mimic interesting solutions in general relativity and modifications and recast the general Painlevé–Gullstrand and FLRW metrics. Finally, we elaborate on a reconstruction procedure for a subclass of off-diagonal cosmological solutions which describe cyclic and ekpyrotic universes, with an emphasis on open issues and observable signatures.

  8. Off-diagonal ekpyrotic scenarios and equivalence of modified, massive and/or Einstein gravity

    Energy Technology Data Exchange (ETDEWEB)

    Vacaru, Sergiu I., E-mail: sergiu.vacaru@uaic.ro [University “Al. I. Cuza” Iaşi, Rector' s Department, 14 Alexandru Lapuşneanu Street, Corpus R, UAIC, Office 323, Iaşi, 700057 (Romania); Max-Planck-Institute for Physics, Werner-Heisenberg-Institute, Foehringer Ring 6, München, D-80805 (Germany); Riemann Center for Geometry and Physics, Leibniz Universität Hannover, Welfengarten 1, 30167 Hannover (Germany)

    2016-01-10

    Using our anholonomic frame deformation method, we show how generic off-diagonal cosmological solutions depending, in general, on all spacetime coordinates and undergoing a phase of ultra-slow contraction can be constructed in massive gravity. In this paper, there are found and studied new classes of locally anisotropic and (in)homogeneous cosmological metrics with open and closed spatial geometries. The late time acceleration is present due to effective cosmological terms induced by nonlinear off-diagonal interactions and graviton mass. The off-diagonal cosmological metrics and related Stückelberg fields are constructed in explicit form up to nonholonomic frame transforms of the Friedmann–Lamaître–Robertson–Walker (FLRW) coordinates. We show that the solutions include matter, graviton mass and other effective sources modeling nonlinear gravitational and matter fields interactions in modified and/or massive gravity, with polarization of physical constants and deformations of metrics, which may explain certain dark energy and dark matter effects. There are stated and analyzed the conditions when such configurations mimic interesting solutions in general relativity and modifications and recast the general Painlevé–Gullstrand and FLRW metrics. Finally, we elaborate on a reconstruction procedure for a subclass of off-diagonal cosmological solutions which describe cyclic and ekpyrotic universes, with an emphasis on open issues and observable signatures.

  9. A discrete Fourier-encoded, diagonal-free experiment to simplify homonuclear 2D NMR correlations

    Science.gov (United States)

    Huang, Zebin; Guan, Quanshuai; Chen, Zhong; Frydman, Lucio; Lin, Yulan

    2017-07-01

    Nuclear magnetic resonance (NMR) spectroscopy has long served as an irreplaceable, versatile tool in physics, chemistry, biology, and materials sciences, owing to its ability to study molecular structure and dynamics in detail. In particular, the connectivity of chemical sites within molecules, and thereby molecular structure, becomes visible by multi-dimensional NMR. Homonuclear correlation experiments are a powerful tool for identifying coupled spins. Generally, diagonal peaks in these correlation spectra display the strongest intensities and do not offer any new information beyond the standard one-dimensional spectrum, whereas weaker, symmetrically placed cross peaks contain most of the coupling information. The cross peaks near the diagonal are often affected by the tails of strong diagonal peaks or even obscured entirely by the diagonal. In this paper, we demonstrate a homonuclear encoding approach based on imparting a discrete phase modulation of the targeted cross peaks and combine it with a site-selective sculpting scheme, capable of simplifying the patterns arising in these 2D correlation spectra. The theoretical principles of the new methods are laid out, and experimental observations are rationalized on the basis of theoretical analyses. The ensuing techniques provide a new way to retrieve 2D coupling information within homonuclear spin systems, with enhanced sensitivity, speed, and clarity.

  10. 对角方阵的变换群%Transformaion Group of Diagonal Square Matrices

    Institute of Scientific and Technical Information of China (English)

    张世德; 李程

    2011-01-01

    In this paper,we show that the transformaion group of diagonal square matrices is a subgroup of direct product Sn × Sn of symetric groups of order n, if the sets of elements of each row, each column and the two diagonals are kept constant, respectively. The diagonal Latin squares, pair of orthogonal daigonal Latin squares, magic squares, magic squares of high dgree, addition multiplacation magic squares are diagonal square matrices. This paper plays an important role in the study of construction and enumeration of the objects above.%在不改变对角方阵各行、各列、主对角线、次对角线的元素之集的条件下,其变换群是n次对称群Sn的直积Sn×Sn的子群,因对角拉丁方、对角拉丁方正交侣、幻方、高次幻方、加乘幻方均属此类方阵,本文对构作这类对象及研究它们的计数有重要意义.

  11. An integrated chronic disease management model: a diagonal approach to health system strengthening in South Africa.

    Science.gov (United States)

    Mahomed, Ozayr Haroon; Asmall, Shaidah; Freeman, Melvyn

    2014-11-01

    The integrated chronic disease management model provides a systematic framework for creating a fundamental change in the orientation of the health system. This model adopts a diagonal approach to health system strengthening by establishing a service-linked base to training, supervision, and the opportunity to try out, assess, and implement integrated interventions.

  12. Magnitudes of gluteus medius muscle activation during standing hip joint movements in spiral-diagonal patterns using elastic tubing resistance.

    Science.gov (United States)

    Youdas, James W; Adams, Kady E; Bertucci, John E; Brooks, Koel J; Steiner, Meghan M; Hollman, John H

    2015-01-01

    The aim of this study was to simultaneously quantify electromyographic (EMG) activation levels (% maximum voluntary isometric contraction [MVIC]) within the gluteus medius muscles on both moving and stance limbs across the performance of four proprioceptive neuromuscular facilitation (PNF) spiral-diagonal patterns in standing using resistance provided by elastic tubing. Differential EMG activity was recorded from the gluteus medius muscle of 26 healthy participants. EMG signals were collected with surface electrodes at a sampling frequency of 1000 Hz during three consecutive repetitions of each spiral-diagonal movement pattern. Significant differences existed among the four-spiral-diagonal movement patterns (F3,75 = 19.8; p < 0.001). The diagonal two flexion [D2F] pattern produced significantly more gluteus medius muscle recruitment (50 SD 29.3% MVIC) than any of the other three patterns and the diagonal one extension [D1E] (39 SD 37% MVIC) and diagonal two extension [D2E] (35 SD 29% MVIC) patterns generated more gluteus medius muscle recruitment than diagonal one flexion [D1F] (22 SD 21% MVIC). From a clinical efficiency standpoint, a fitness professional using the spiral-diagonal movement pattern of D2F and elastic tubing with an average peak tension of about 9% body mass may be able to concurrently strengthen the gluteus medius muscle on both stance and moving lower limbs.

  13. 膝关节后纵隔解剖特点及其在关节镜手术中的应用%ANATOMIC FEATURES OF POSTERIOR SEPTUM OF KNEE JOINT AND ITS APPLICATION IN POSTERIOR TRANS-SEPTAL PORTAL FOR ARTHROSCOPIC SURGERY

    Institute of Scientific and Technical Information of China (English)

    孙金鹏; 熊依林; 雷光华

    2013-01-01

    目的 总结膝关节后纵隔解剖特点及其在关节镜手术中,尤其是跨后纵隔通路建立中的应用. 方法 查阅近年国内外有关膝关节后纵隔及膝关节镜的文献,并进行归纳分析. 结果 后纵隔上部血管、神经较丰富,在胫骨平台水平与腘动脉紧邻:将膝关节后室分为较小的外室和较大的内室.膝关节镜下建立跨后纵隔通道时应屈膝90°,方向由外向内,从后纵隔中间靠下部穿过较安全. 结论 跨后纵隔通道使膝关节镜应用范围大大扩展,但通道建立方法并不统一,只有综合考虑后纵隔解剖学特点,才能减少手术并发症.%Objective To summarize the anatomic features of the posterior septum of the knee joint and its application in posterior trans-septal portal for arthroscopic surgery. Methods The literature related to posterior septum of the knee joint and arthroscopic surgery was extensively reviewed and analyzed. Results The posterior septum of the knee joint has more mechanoreceptors and blood vessels in the upper part, which are close to arteria popliteal at the tibial plateau level; the posterior compartment is divided into wider posteromedial and narrower posterolateral compartments. A safe arthroscopic trans-septal portal is established, in the knee flexion of 90°, in a lateral-to-medial direction, and with an inserting location below the middle of posterior septum. Conclusion The establishment method of posterior trans-septal portal is not uniform and all the features of posterior septum should be considered to decrease the complications.

  14. Post-ablative reconstruction of the medial canthus and medial orbital wall using conchal cartilage graft with three illustrative cases.

    Science.gov (United States)

    Dagregorio, G; Darsonval, V

    2005-12-01

    When the medial third of the upper or lower eyelid has to be reconstructed after full-thickness tumour excision, we usually use Hübner tarsomarginal grafts, but when medial canthal lesions spread to the medial orbital wall without invading the orbital margin, conchal graft becomes our first surgical option. Previously reported solutions to this difficult problem are few and concern more directly medial orbital wall fractures. We found no article dealing specifically with the use of conchal graft in post-ablative reconstruction of the medial orbital wall. Nevertheless the concha presents great advantages over bone grafting or rib cartilage, because it is more flexible and malleable. And it is less prone to extrusion or infection as may be allografts implants. It is a very effective way to repair medial orbital defects, but graft reorientation must be perfect to match exactly the medial orbital wall concavity.

  15. SEPTO-OPTICDYSPLASIA WITH AN ANTERIOR ENCEPHALOCELE AND INTACT SEPTUM PELLUCIDUM: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Z. Razavi

    2008-06-01

    Full Text Available ObjectiveThe diagnosis of de Morsier syndrome or septo-optic dysplasia is made on the basis of the diagnosis of optic nerve hypoplasia. Septo-optic dysplasia is defined by a variable combination of dysgenesis of midline brain structures including optic nerve hypoplasia and hypothalamic-pituitary dysfunction often associated with a wide variety of brain malformations of cortical development.The importance of direct ophthalmoscopy of optic nerve abnormalities is stressed, as well as of magnetic resonance imaging, which has become a guideline in the classification of  this syndrome This article reports a 19-year-old female with bilateral optic nerve  hypoplasia,anterior encephalocele and intact septum pellucidum. She was diagnosed withdiabetes insipidus, short stature and the history of seizure.

  16. Division genes in Escherichia coli are expressed coordinately to cell septum requirements by gearbox promoters.

    Science.gov (United States)

    Aldea, M; Garrido, T; Pla, J; Vicente, M

    1990-11-01

    The cell division ftsQAZ cluster and the ftsZ-dependent bolA morphogene of Escherichia coli are found to be driven by gearboxes, a distinct class of promoters characterized by showing an activity that is inversely dependent on growth rate. These promoters contain specific sequences upstream from the mRNA start point, and their -10 region is essential for the inverse growth rate dependence. Gearbox promoters are essential for driving ftsQAZ and bolA gene expression so that the encoded products are synthesized at constant amounts per cell independently of cell size. This mode of regulation would be expected for the expression of proteins that either play a regulatory role in cell division or form a stoichiometric component of the septum, a structure that, independently of cell size and growth rate, is produced once per cell cycle.

  17. Pulmonary Atresia with Intact Ventricular Septum and Absence of Tricuspid Valve. A Report of Four Cases

    Directory of Open Access Journals (Sweden)

    Adel E. González Morejón

    2013-12-01

    Full Text Available Pulmonary atresia with intact ventricular septum suggests a simple congenital heart malformation. However, nothing could be further from the truth. Among the morphological peculiarities of this condition, the presence of congenitally unguarded tricuspid valve orifice is rarely observed. The present paper aims at describing a series of four patients with both malformations detected in the William Soler Children’s Heart Center from 1986 through 2012. Echocardiographic diagnosis could be accurately performed in the last two patients; identification of the initial cases was established by the findings at necropsy. All patients underwent Blalock – Taussig shunt as initial palliative treatment, which was associated with balloon atrioseptostomy in two cases. Only one of the last children mentioned survived. Vital prognosis of patients suffering from this association of malformations lies in early echocardiographic detection.

  18. The embryonic septum and ventral pallium, new sources of olfactory cortex cells.

    Directory of Open Access Journals (Sweden)

    María Laura Ceci

    Full Text Available The mammalian olfactory cortex is a complex structure located along the rostro-caudal extension of the ventrolateral prosencephalon, which is divided into several anatomically and functionally distinct areas: the anterior olfactory nucleus, piriform cortex, olfactory tubercle, amygdaloid olfactory nuclei, and the more caudal entorhinal cortex. Multiple forebrain progenitor domains contribute to the cellular diversity of the olfactory cortex, which is invaded simultaneously by cells originating in distinct germinal areas in the dorsal and ventral forebrain. Using a combination of dye labeling techniques, we identified two novel areas that contribute cells to the developing olfactory cortices, the septum and the ventral pallium, from which cells migrate along a radial and then a tangential path. We characterized these cell populations by comparing their expression of calretinin, calbindin, reelin and Tbr1 with that of other olfactory cell populations.

  19. Giant aneurysm of the atrial septum associated with premature closure of foramen ovale

    Directory of Open Access Journals (Sweden)

    Romaguera Rita L

    2005-08-01

    Full Text Available Abstract Premature closure or restriction of foramen ovale (PCFO is a rare congenital anomaly that can lead to a wide spectrum of cardiac malformations. This spectrum of secondary malformations appears to depend on the gestational timing of closure of the foramen ovale and to the degree of restriction. Earlier in the gestation, closure of the foramen has been associated with severe hypoplasia of the left ventricle whereas later closure has been associated with right heart failure and rarely with the formation of an aneurysm of the atrial septum. We describe the case of a 1 day old infant in whom PCFO resulted in severe right heart failure in addition to the formation of a giant atrial septal aneurysm.

  20. Direct carotid cavernous fistula after submucous resection of the nasal septum.

    Science.gov (United States)

    Bizri, A R; al-Ajam, M; Zaytoun, G; al-Kutoubi, A

    2000-01-01

    A carotid cavernous fistula (CCF) is an abnormal arteriovenous anastomosis between the carotid artery and the cavernous sinus. Etiologies of this condition reported in the literature so far include facial trauma, rupture of an intracavernous aneurysm of the carotid artery, Ehler-Danlos syndrome and fibromuscular dysplasia of the cerebral arteries. Such fistulae were reported as complications of rhinoplasty, transsphenoidal surgery, embolization of cavernous sinus meningioma, and rhinocerebral mucormycosis. CCF may also occur spontaneously in children or as a congenital malformation. However, to our knowledge, submucous resection of the nasal septum has not been reported before to cause direct carotid-cavernous fistula. CT and angiographic findings are presented and a review of the literature for reported causes of CCF is made as well as a brief discussion of the possible pathophysiology.

  1. Arthroscopic Classification of the Lesions of the Dorsal Capsulo-Scapholunate Septum (DCSS) of the Wrist.

    Science.gov (United States)

    Van Overstraeten, Luc; Camus, Emmanuel J

    2016-09-01

    The dorsal capsulo-scapholunate septum (DCSS) is an anatomic structure linking the scapholunate ligament and the dorsal capsule of the wrist. It should be a predynamic scapholunate stabilizer. The authors, using their experience for the extrinsic ligaments testing, suggest an arthroscopic testing of the DCSS. The status could be graded in 4 stages according to the trampoline aspect and to the fiber attachment. They report a preliminary study on a series of 53 arthroscopies made between January 2014 and December 2015 with evaluation of scapholunate ligament instability and DCSS laxity. There is a significant correlation between the lesional stage of the DCSS and the arthroscopic predynamic scapholunate instability stage (P<0.01).

  2. Prevalence and characteristics of cavum septum pellucidum in schizophrenia: A 16 slice computed tomography study

    Directory of Open Access Journals (Sweden)

    Sourav Khanra

    2016-01-01

    Full Text Available Objective: Several significant midline abnormalities including cavum septum pellucidum (CSP have been reported in schizophrenia. However, not all studies were able to replicate similar findings. Furthermore, very few of them were conducted with large samples. Methods: CSP was identified and graded with 16 slice computed tomography (CT machine in 138 patients of schizophrenia and 64 controls. Results: We found 21.0% of patients in schizophrenia group had abnormal CSP compared to only 9.4% in control group (P = 0.047. Grade III was most frequent type (19.6% in schizophrenia group. Conclusions: Our study adds to the existing literature suggesting abnormal CSP may reflect neurodevelopmental process in schizophrenia. The strength of our study was larger sample size. Limitations were use of CT, male predominance in schizophrenia group, the inclusion of nonpsychiatric patients in control group.

  3. The diagonal and off-diagonal AC conductivity of two-dimensional electron gases with contactless Corbino geometry in the quantum Hall regime

    DEFF Research Database (Denmark)

    Petersen, Christian Leth; Hansen, Ole Per

    1996-01-01

    We have investigated the AC conductivity elements in the quantum Hall regime of two-dimensional electron gases coupled capacitively to electrodes with Corbino geometry. The samples are GaAlAs/GaAs single heterostructures, and the measurements are made at low frequencies, up to 20 kHz. The diagonal...... conductivity is derived from magnetocapacitance measurements. It increases with increasing frequency according to a power law at integer filling factors. The exponent of the power law depends on both temperature and filling factor. Ratios between Hall conductivities at different filling factors are obtained...

  4. Surco diagonal en el lóbulo de la oreja: ¿signo de enfermedad arterial coronaria? Diagonal earlobe crease: a sign of coronary artery disease?

    Directory of Open Access Journals (Sweden)

    Sebastián B. Lamot

    2007-08-01

    Full Text Available El surco diagonal es un signo encontrado en el lóbulo de la oreja, que estaría relacionado con la enfermedad arterial coronaria. Nuestro objetivo fue estudiar la utilidad del signo. Se examinaron 104 pacientes (entre 30 y 80 años clasificados por sexo y edad. Cuarenta y nueve tenían enfermedad arterial coronaria diagnosticada por coronariografía (obstrucción > del 70% en una de las grandes arterias y/o gamagrafía de perfusión miocárdica con Talio 201 (defecto fijo. El grupo control estuvo compuesto por 55 pacientes (asintomáticos, con electrocardiograma normal. Los datos obtenidos fueron sensibilidad (61.2%, especificidad (78.2%, valor predictivo positivo de (71.4% y valor predictivo negativo (69.3%.. Observamos una relación significativa entre la presencia de surco diagonal y enfermedad arterial coronaria. Consideramos que este signo podría resultar de utilidad en la práctica clínica, fundamentalmente para los pacientes entre 30 y 60 años.The diagonal earlobe crease is a sign theorically related to coronary artery disease. The purpose of this study was to prove the usefulness of this sign. A total of 104 patients were examined (ages 30 to 80 grouped by age and sex. Forty nine of them were diagnosed of having coronary artery disease by coronary angiography (a 70% obstruction of one of the major arteries, and/or myocardial perfusion imaging with Thallium 201 (fixed defects. The control group included 55 patients (asymptomatic with normal electrocardiogram. Data here obtained included sensitivity (61.2%, specificity (78.2%, positive predictive value (71.4% and negative predictive value (69.3%. We found a significant relation between the presence of the diagonal earlobe crease and coronary artery disease. We consider it a sign that could prove useful in clinical practice, mainly among patients aged between 30 and 60.

  5. LocZ Is a New Cell Division Protein Involved in Proper Septum Placement in Streptococcus pneumoniae

    Science.gov (United States)

    Holečková, Nela; Molle, Virginie; Buriánková, Karolína; Benada, Oldřich; Kofroňová, Olga; Ulrych, Aleš; Branny, Pavel

    2014-01-01

    ABSTRACT How bacteria control proper septum placement at midcell, to guarantee the generation of identical daughter cells, is still largely unknown. Although different systems involved in the selection of the division site have been described in selected species, these do not appear to be widely conserved. Here, we report that LocZ (Spr0334), a newly identified cell division protein, is involved in proper septum placement in Streptococcus pneumoniae. We show that locZ is not essential but that its deletion results in cell division defects and shape deformation, causing cells to divide asymmetrically and generate unequally sized, occasionally anucleated, daughter cells. LocZ has a unique localization profile. It arrives early at midcell, before FtsZ and FtsA, and leaves the septum early, apparently moving along with the equatorial rings that mark the future division sites. Consistently, cells lacking LocZ also show misplacement of the Z-ring, suggesting that it could act as a positive regulator to determine septum placement. LocZ was identified as a substrate of the Ser/Thr protein kinase StkP, which regulates cell division in S. pneumoniae. Interestingly, homologues of LocZ are found only in streptococci, lactococci, and enterococci, indicating that this close phylogenetically related group of bacteria evolved a specific solution to spatially regulate cell division. PMID:25550321

  6. Ectopic Acromegaly Arising from a Pituitary Adenoma within the Bony Intersphenoid Septum of a Patient with Empty Sella Syndrome

    Science.gov (United States)

    Arzamendi, Audrey E.; Shahlaie, Kiarash; Latchaw, Richard E.; Lechpammer, Mirna; Arzumanyan, Hasmik

    2016-01-01

    Objective  To describe the work-up and treatment of rare ectopic acromegaly caused by a biopsy-proven somatotroph pituitary adenoma located within the bony intersphenoid septum of a patient with empty sella syndrome (ESS). Methods  We report the presentation, clinical course, diagnostic work-up, and lesion localization and treatment challenges encountered in a 55-year-old patient, with a brief review of relevant literature. Results  A 55-year-old African-American man presented with acromegaly and ESS. Attempts to definitively localize the causative tumor were unsuccessful, though petrosal sinus sampling supported central growth hormone production and imaging suggested bone-enclosed subsellar pituitary tissue. Endoscopic endonasal transphenoidal exploration was undertaken with resection of a somatotroph pituitary microadenoma, and subsequent clinical improvement and biochemical remission. Retrospective review revealed the patient's pituitary to have been located ectopically within a unique bony intersphenoid septum. Conclusion  This report describes the first known case of an ectopic pituitary adenoma located within the midline bony intersphenoid septum, which we postulate to have resulted from anomalous embryological pituitary migration. Intra-intersphenoid septal tumors should be considered in cases of apparent central acromegaly with ESS or absence of tumor tissue within the paranasal sinuses or other peripheral locations. Indexing  Acromegaly, ESS, pituitary adenoma, sphenoid sinus septum. PMID:27468406

  7. Atrial tachycardia originating from the atrial septum in a patient with dextrocardia and complex structural heart disease.

    Science.gov (United States)

    Niu, Ya-Lei; Chang, Shih-Lin; Lin, Yenn-Jiang; Lo, Li-Wei; Hu, Yu-Feng; Lee, Pi-Chang; Chen, Shih-Ann

    2012-10-01

    We report a case with dextrocardia, corrected transposition of the great arteries. He also had an atrial septum defect (ASD) with patch repair. Activation map showed a centrifugal activation from a focal origin on the systemic lower left atrial ASD patch. Ablation of the origin can terminate the atrial tachycardia.

  8. Transcatheter pulmonary valve perforation using chronic total occlusion wire in pulmonary atresia with intact ventricular septum

    Science.gov (United States)

    Bakhru, Shweta; Marathe, Shilpa; Saxena, Manish; Verma, Sudeep; Saileela, Rajan; Dash, Tapan K; Koneti, Nageswara Rao

    2017-01-01

    Background: Perforation of pulmonary valve using radiofrequency ablation in pulmonary atresia with intact ventricular septum (PA IVS) is a treatment of choice. However, significant cost of the equipment limits its utility, especially in the developing economies. Objective: To assess the feasibility, safety, and efficacy of perforation of pulmonary valve using chronic total occlusion (CTO) wires in patients with PA IVS as an alternative to radiofrequency ablation. Methods: This is a single-center, nonrandomized, retrospective study conducted during June 2008 to September 2015. Twenty-four patients with PA IVS were selected for the procedure during the study period. The median age and weight of the study population were 8. days and 2.65 kg, respectively. Four patients were excluded after right ventricular angiogram as they showed right ventricular-dependent coronary circulation. The pulmonary valve perforation was attempted using various types of CTO wires based on the tip load with variable penetrating characteristics. Results: The procedure was successful in 16 of twenty patients using CTO wires: Shinobi in nine, Miracle in four, CROSS-IT in two, and Conquest Pro in one. Two patients had perforation of right ventricular outflow tract (RVOT). Pericardiocentesis was required in one patient to relieve cardiac tamponade. Later, the same patient underwent successful hybrid pulmonary valvotomy. The other patient underwent ductus arteriosus (DA) stenting. Balloon atrial septostomy was needed in three cases with systemic venous congestion. Desaturation was persistent in five cases necessitating DA or RVOT stenting to augment pulmonary blood flow. There were two early and two late deaths. The mean follow-up was 22.66 ± 16 months. Three patients underwent one and half ventricle repair and one Blalock–Taussig shunt during follow-up. Conclusion: Perforation of the pulmonary valve can be done successfully using CTO wires in selected cases of pulmonary atresia with intact

  9. Microsurgical treatment of medial sphenoid ridge meningioma

    Directory of Open Access Journals (Sweden)

    Wei-qi HE

    2011-02-01

    Full Text Available Objective To explore the microsurgical technique of medial sphenoid ridge meningioma resectional therapy.Methods The clinical data were retrospectively analyzed of 29 patients(13 males and 16 females;aged 18-68 years with average of 42 years;duration of disease was 5 months to 8 years,averaged 28 months with medial sphenoidal ridge meningioma and admitted from Jan.2005 to Jan.2010.The anatomical relationship of the tumor to surrounding structures was assessed intraoperatively,the tumor was then completely resected through cutting off the tumor supplying vessels,shrinking the tumor volume and separating the tumors from adjacent vessels and nerves.All the patients were followed up for 4 months to 4 years.Results Of the 29 cases,20 got total tumor removal,7 got subtotal and 2 got partial tumor removal.Of the 20 patients with obviously preoperative visual impairment,12 were obviously relieved,6 showed no improvement and 2 got symptoms aggravation.Hemiplegia occurred in 2 cases and oculomoter nerve palsy in 6 cases.There was no death after surgery.A 6 months to 4 years follow-up showed that no recurrence was found in 27 patients with tumor resection level of Simpson I and II,2 patients with tumor resection level of Simpson III received postoperative radiotherapy or gamma knife surgery,and 1 recurred and received reoperation.Conclusions Fine intraoperative assessment of the anatomical relationship of the tumor to surrounding structures,separating and excising tumor according to the assessed result is the key of medial sphenoid ridge meningioma resection,and the tumor resection is favorable to visual rehabilitation and tumor control.

  10. Biomechanical consequences of patellar component medialization in total knee arthroplasty.

    Science.gov (United States)

    Anglin, Carolyn; Brimacombe, Jill M; Wilson, David R; Masri, Bassam A; Greidanus, Nelson V; Tonetti, Jérôme; Hodgson, Antony J

    2010-08-01

    The optimal amount of patellar component medialization in knee arthroplasty is unknown. We measured the impact, on patellofemoral kinematics and contact force distribution, of 0.0-, 2.5-, and 5.0-mm patellar component medialization in 7 cadaveric specimens implanted with knee arthroplasty components. The knees were flexed dynamically in a weight-bearing rig. Medialization led to lateral shift of the patellar bone, slight medial shift of the patellar component in the femoral groove, lateral tilt of the patella, reduced patellofemoral contact force in later flexion, and lateral shift of the center of pressure in early flexion. Effects on shift and tilt were proportional to the amount of medialization. As a result of this investigation, we recommend medializing the patellar component slightly-on the order of 2.5 mm. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  11. Fundamental Group and Euler Characteristic of Permutation Products and Fat Diagonals

    CERN Document Server

    Kallel, Sadok

    2010-01-01

    Permutation products and their various "fat diagonal" subspaces are studied from the topological and geometric point of view. We first write down an expression for the fundamental group of any permutation product of a connected space $X$, having the homotopy type of a simplicial complex, in terms of $\\pi_1(X)$ and $H_1(X;{\\mathbb Z})$. We then prove that the fundamental group of the configuration space of $n$-points on $X$ of which multiplicities do not exceed $n/2$ coincides with $H_1(X;{\\mathbb Z})$. Useful additivity properties for the Euler characteristic are then spelled out and used to give explicit formulae for the Euler characteristics of various fat diagonals. Several examples and calculations are included.

  12. Diagonal slice spectrum assisted optimal scale morphological filter for rolling element bearing fault diagnosis

    Science.gov (United States)

    Li, Yifan; Liang, Xihui; Zuo, Ming J.

    2017-02-01

    This paper presents a novel signal processing scheme, diagonal slice spectrum assisted optimal scale morphological filter (DSS-OSMF), for rolling element fault diagnosis. In this scheme, the concept of quadratic frequency coupling (QFC) is firstly defined and the ability of diagonal slice spectrum (DSS) in detection QFC is derived. The DSS-OSMF possesses the merits of depressing noise and detecting QFC. It can remove fault independent frequency components and give a clear representation of fault symptoms. A simulated vibration signal and experimental vibration signals collected from a bearing test rig are employed to evaluate the effectiveness of the proposed method. Results show that the proposed method has a superior performance in extracting fault features of defective rolling element bearing. In addition, comparisons are performed between a multi-scale morphological filter (MMF) and a DSS-OSMF. DSS-OSMF outperforms MMF in detection of an outer race fault and a rolling element fault of a rolling element bearing.

  13. Direct current hopping conductance in one-dimensional diagonal disordered systems

    Institute of Scientific and Technical Information of China (English)

    Ma Song-Shan; Xu Hui; Liu Xiao-Liang; Xiao Jian-Rong

    2006-01-01

    Based on a tight-binding disordered model describing a single electron band, we establish a direct current (dc) electronic hopping transport conductance model of one-dimensional diagonal disordered systems, and also derive a dc conductance formula. By calculating the dc conductivity, the relationships between electric field and conductivity and between temperature and conductivity are analysed, and the role played by the degree of disorder in electronic transport is studied. The results indicate the conductivity of systems decreasing with the increase of the degree of disorder, characteristics of negative differential dependence of resistance on temperature at low temperatures in diagonal disordered systems, and the conductivity of systems decreasing with the increase of electric field, featuring the non-Ohm's law conductivity.

  14. Solving an inverse eigenvalue problem with triple constraints on eigenvalues, singular values, and diagonal elements

    Science.gov (United States)

    Wu, Sheng-Jhih; Chu, Moody T.

    2017-08-01

    An inverse eigenvalue problem usually entails two constraints, one conditioned upon the spectrum and the other on the structure. This paper investigates the problem where triple constraints of eigenvalues, singular values, and diagonal entries are imposed simultaneously. An approach combining an eclectic mix of skills from differential geometry, optimization theory, and analytic gradient flow is employed to prove the solvability of such a problem. The result generalizes the classical Mirsky, Sing-Thompson, and Weyl-Horn theorems concerning the respective majorization relationships between any two of the arrays of main diagonal entries, eigenvalues, and singular values. The existence theory fills a gap in the classical matrix theory. The problem might find applications in wireless communication and quantum information science. The technique employed can be implemented as a first-step numerical method for constructing the matrix. With slight modification, the approach might be used to explore similar types of inverse problems where the prescribed entries are at general locations.

  15. Multiple Quenches, Jarzynski Equality and Diagonal Entropy: A Novel Approach For Non-equilibrium Dynamics

    CERN Document Server

    Ngo, Van A

    2013-01-01

    We propose a combination between the theory of diagonal entropy representing far-from-equilibrium ensembles and Jarzynski Equality to explore thermalization effects on thermodynamic quantities such as temperature, entropy, mechanical work and free-energy changes. Applying the theory to a quantum harmonic oscillator, we find that diagonal entropy offers a definition of temperature for closed systems far from equilibrium, and a better sampling of reaction pathways than the conventional von Neumann entropy. We also apply the theory to a many-body system of hard-core boson lattice, and discuss the ideas of how to estimate temperature, entropy and measure work distribution functions. The theory suggests a powerful technique to study non-equilibrium dynamics in quantum systems by means of performing work in a series of quenches.

  16. Quasilocal charges and the complete GGE for field theories with non-diagonal scattering

    CERN Document Server

    Vernier, Eric

    2016-01-01

    It has recently been shown that some integrable spin chains possess a set of quasilocal conserved charges, with the classic example being the spin-$\\frac{1}{2}$ XXZ Heisenberg chain. These charges have been proven to be essential for properly describing stationary states after a quantum quench, and must be included in the generalized Gibbs ensemble (GGE). We find that similar charges are also necessary for the GGE description of integrable quantum field theories with non-diagonal scattering. A stationary state in a non-diagonal scattering theory is completely specified by fixing the mode-ocuppation density distributions of physical particles, as well auxiliary particles which carry no energy or momentum. We show that the set of conserved charges with integer Lorentz spin, related to the integrability of the model, are unable to fix the distributions of these auxiliary particles, since these charges can only fix kinematical properties of physical particles. The field theory analogs of quasilocal lattice charge...

  17. Exact Solutions in Modified Massive Gravity and Off-Diagonal Wormhole Deformations

    CERN Document Server

    Vacaru, Sergiu I

    2014-01-01

    There are explored off-diagonal deformations of "prime" metrics in Einstein gravity (for instance, for wormhole configurations) into "target" exact solutions in f(R,T)-modified and massive/ bi-metric gravity theories. The new classes of solutions may posses, or not, Killing symmetries and can be characterized by effective induced masses, anisotropic polarized interactions and cosmological constants. For nonholonomic deformations with (conformal) ellipsoid/ toroid and/or solitonic symmetries and, in particular, for small eccentricity rotoid configurations, we can generate wormholes like objects matching external black ellipsoid - de Sitter geometries. We conclude that there are nonholonomic transforms and/or non-trivial limits to exact solutions in general relativity when modified/ massive gravity effects are modeled by off-diagonal and/or nonholonomic parametric interactions.

  18. Improved diagonal queue medical image steganography using Chaos theory, LFSR, and Rabin cryptosystem.

    Science.gov (United States)

    Jain, Mamta; Kumar, Anil; Choudhary, Rishabh Charan

    2016-09-09

    In this article, we have proposed an improved diagonal queue medical image steganography for patient secret medical data transmission using chaotic standard map, linear feedback shift register, and Rabin cryptosystem, for improvement of previous technique (Jain and Lenka in Springer Brain Inform 3:39-51, 2016). The proposed algorithm comprises four stages, generation of pseudo-random sequences (pseudo-random sequences are generated by linear feedback shift register and standard chaotic map), permutation and XORing using pseudo-random sequences, encryption using Rabin cryptosystem, and steganography using the improved diagonal queues. Security analysis has been carried out. Performance analysis is observed using MSE, PSNR, maximum embedding capacity, as well as by histogram analysis between various Brain disease stego and cover images.

  19. Off-Diagonal Deformations of Kerr Metrics and Black Ellipsoids in Heterotic Supergravity

    CERN Document Server

    Vacaru, Sergiu I

    2016-01-01

    Geometric methods for constructing exact solutions of motion equations with first order $\\alpha ^{\\prime }$ corrections to the heterotic supergravity action implying a non-trivial Yang-Mills sector and six dimensional, 6-d, almost-K\\"{a}hler internal spaces are studied. In 10-d spacetimes, general parametrizations for generic off-diagonal metrics, nonlinear and linear connections and matter sources, when the equations of motion decouple in very general forms are considered. This allows us to construct a variety of exact solutions when the coefficients of fundamental geometric/physical objects depend on all higher dimensional spacetime coordinates via corresponding classes of generating and integration functions, generalized effective sources and integration constants. Such generalized solutions are determined by generic off-diagonal metrics and nonlinear and/or linear connections. In particular, as configurations which are warped/compactified to lower dimensions and for Levi-Civita connections. The correspond...

  20. Exact solutions in modified massive gravity and off-diagonal wormhole deformations

    Energy Technology Data Exchange (ETDEWEB)

    Vacaru, Sergiu I. [Alexandru Ioan Cuza University, Rector' s Office, Iasi (Romania); CERN, Theory Division, Geneva 23 (Switzerland)

    2014-03-15

    We explore off-diagonal deformations of 'prime' metrics in Einstein gravity (for instance, for wormhole configurations) into 'target' exact solutions in f(R,T)-modified and massive/bi-metric gravity theories. The new classes of solutions may, or may not, possess Killing symmetries and can be characterized by effective induced masses, anisotropic polarized interactions, and cosmological constants. For nonholonomic deformations with (conformal) ellipsoid/ toroid and/or solitonic symmetries and, in particular, for small eccentricity rotoid configurations, we can generate wormhole-like objects matching an external black ellipsoid--de Sitter geometries. We conclude that there are nonholonomic transforms and/or non-trivial limits to exact solutions in general relativity when modified/massive gravity effects are modeled by off-diagonal and/or nonholonomic parametric interactions. (orig.)

  1. A Diagnostic Supportive Sign for the Cause of Death Diagonal Ear Lobe Crease

    Directory of Open Access Journals (Sweden)

    Birol Demirel

    2005-08-01

    Full Text Available Coronary artery disease is a major cause of natural death. The high incidence and mortality of these diseases arised a need to investigate possible risk factors beyond well known. Diagonal ear lobe crease (DEC, was the physical sign, described in 1973. We investigated the possibility of DEC as a helpful predictive sign in the postmortem examination of forensic sudden death cases. The angiographic results revealed that whenever the percentages of the stenosis in left descending coronary artery, circumflex artery and right coronary artery increased, the incidence of the DEC did so accordingly. These results were correlated with the previous studies reporting significant correlation between coronary artery disease and the DEC. Particularly, in the absence of supportive medical history and without a physical sign of trauma, the presence of DEC could well be a supportive sign for the physician to consider the coronary artery disease as a cause of death. Key words: Diagonal ear lobe crease, coronary artery disease, death investigation

  2. Identifiability of Complex Blind Source Separation via Non-Unitary Joint Diagonalization

    CERN Document Server

    Kleinsteuber, Martin

    2011-01-01

    Identifiability analysis of complex Blind Source Separation (BSS), i.e. to study under what conditions the BSS problem can be solved, is a long-standing and most critical problem in the community. It serves not only as the indicator to solvability of the BSS problem, but also as the constructive ground for developing efficient algorithms. Various BSS methods are based on jointly diagonalizing a set of matrices, which are generated using second- or higher-order statistics. The present work provides a general result on the uniqueness conditions of matrix joint diagonalization. It unifies all existing results on the identifiability conditions of complex BSS, with respect to non-circularity, non-stationarity, non-whiteness, and non-Gaussianity. Additionally, following the main identifiability result, a solution for complex BSS is proposed. It is given in closed form in terms of an eigenvalue and a singular value decomposition of two matrices.

  3. The medial tibial stress syndrome. A cause of shin splints.

    Science.gov (United States)

    Mubarak, S J; Gould, R N; Lee, Y F; Schmidt, D A; Hargens, A R

    1982-01-01

    The medial tibial stress syndrome is a symptom complex seen in athletes who complain of exercise-induced pain along the distal posterior-medial aspect of the tibia. Intramuscular pressures within the posterior compartments of the leg were measured in 12 patients with this disorder. These pressures were not elevated and therefore this syndrome is a not a compartment syndrome. Available information suggests that the medial tibial stress syndrome most likely represents a periostitis at this location of the leg.

  4. CT diagnosis of abnormal transparent septum in clinical meaning%透明隔异常CT诊断的临床意义

    Institute of Scientific and Technical Information of China (English)

    曹连义; 张勇

    2003-01-01

    AIM:Abnormal transparent septum is common in clinical works but little in meaning,so some CT reports are not listed.We collected complete abnormal transparent septum cases to perform comparison analysis between CT diagnosis and clinical data.METHODS:109 abnormal transparent septum diagnosed by CT was compared with symptom of clinics.Axis scanning and no enhanced scanning were used in CT and 2 doctors in charge of sample collection.The 109 cases were excluded with abnormal transparent septum induced by secondary local cerebral atrophy and secondary perforation deformity.RESULTS:There were 15 cases with the fifth ventricle of cerebrum and 22 cases with the fifth and sixth ventricle of cerebrums,10 cases with transparent septum cyst,28 cases with translocation of transparent septum,8 cases with no crack in the forebrain,6 cases with poor development of keratoma and 20 cases of other deformity.CONCLUSION:Abnormal transparent septum cannot be omitted and should be clearly diagnosed by CT.

  5. Self-similar solutions with fat tails for a coagulation equation with diagonal kernel

    CERN Document Server

    Niethammer, Barbara

    2011-01-01

    We consider self-similar solutions of Smoluchowski's coagulation equation with a diagonal kernel of homogeneity $\\gamma < 1$. We show that there exists a family of second-kind self-similar solutions with power-law behavior $x^{-(1+\\rho)}$ as $x \\to \\infty$ with $\\rho \\in (\\gamma,1)$. To our knowledge this is the first example of a non-solvable kernel for which the existence of such a family has been established.

  6. Direct Scaling Analysis of Localization in Single-Particle Quantum Systems on Graphs with Diagonal Disorder

    Energy Technology Data Exchange (ETDEWEB)

    Chulaevsky, Victor, E-mail: victor.tchoulaevski@univ-reims.fr [Universite de Reims, Departement de Mathematiques (France)

    2012-12-15

    We propose a simplified version of the Multi-Scale Analysis of Anderson models on a lattice and, more generally, on a countable graph with polynomially bounded growth of balls, with diagonal disorder represented by an IID or strongly mixing correlated potential. We apply the new scaling procedure to discrete Schroedinger operators and obtain localization bounds on eigenfunctions and eigenfunction correlators in arbitrarily large finite subsets of the graph which imply the spectral and strong dynamical localization in the entire graph.

  7. Zero Energy Anomaly in One-Dimensional Anderson Lattice with Exponentially Correlated Weak Diagonal Disorder

    Institute of Scientific and Technical Information of China (English)

    王宗国; 覃绍京; 康凯; 王垂林

    2012-01-01

    We calculated numerically the localization length of one-dimensional Anderson model with correlated diagonal disorder. For zero energy point in the weak disorder limit, we showed that the localization length changes continuously as the correlation of the disorder increases. We found that higher order terms of the correlation must be included into the current perturbation result in order to give the correct localization length, arid to connect smoothly the anomaly at zero correlation with the perturbation result for large correlation.

  8. Workshop report on large-scale matrix diagonalization methods in chemistry theory institute

    Energy Technology Data Exchange (ETDEWEB)

    Bischof, C.H.; Shepard, R.L.; Huss-Lederman, S. [eds.

    1996-10-01

    The Large-Scale Matrix Diagonalization Methods in Chemistry theory institute brought together 41 computational chemists and numerical analysts. The goal was to understand the needs of the computational chemistry community in problems that utilize matrix diagonalization techniques. This was accomplished by reviewing the current state of the art and looking toward future directions in matrix diagonalization techniques. This institute occurred about 20 years after a related meeting of similar size. During those 20 years the Davidson method continued to dominate the problem of finding a few extremal eigenvalues for many computational chemistry problems. Work on non-diagonally dominant and non-Hermitian problems as well as parallel computing has also brought new methods to bear. The changes and similarities in problems and methods over the past two decades offered an interesting viewpoint for the success in this area. One important area covered by the talks was overviews of the source and nature of the chemistry problems. The numerical analysts were uniformly grateful for the efforts to convey a better understanding of the problems and issues faced in computational chemistry. An important outcome was an understanding of the wide range of eigenproblems encountered in computational chemistry. The workshop covered problems involving self- consistent-field (SCF), configuration interaction (CI), intramolecular vibrational relaxation (IVR), and scattering problems. In atomic structure calculations using the Hartree-Fock method (SCF), the symmetric matrices can range from order hundreds to thousands. These matrices often include large clusters of eigenvalues which can be as much as 25% of the spectrum. However, if Cl methods are also used, the matrix size can be between 10{sup 4} and 10{sup 9} where only one or a few extremal eigenvalues and eigenvectors are needed. Working with very large matrices has lead to the development of

  9. A Parallel Algorithm for Solving Block-diagonal Structured Large Linear System

    Institute of Scientific and Technical Information of China (English)

    SHEN Jie; ZHANG Zhong-lin; CHENG Ji-lin

    2001-01-01

    A parallel algorithm for solving block-diagonal structured large linear system is presented.This algorithm is based on the "gradient-simplex" method. It partitions a large linear system into several small linear subsystems so that they can be solved in parallel. The algorithm has the merit of high speed and is suitable for the large linear systems with less coupling constrains. The efficiency and applicability of the method is also analyzed.

  10. Spin-12 XYZ model revisit: General solutions via off-diagonal Bethe ansatz

    Directory of Open Access Journals (Sweden)

    Junpeng Cao

    2014-09-01

    Full Text Available The spin-12 XYZ model with both periodic and anti-periodic boundary conditions is studied via the off-diagonal Bethe ansatz method. The exact spectra of the Hamiltonians and the Bethe ansatz equations are derived by constructing the inhomogeneous T–Q relations, which allow us to treat both the even N (the number of lattice sites and odd N cases simultaneously in a unified approach.

  11. Diagonal rejection-based minimum variance distortionless response for fiber underwater acoustic array

    Science.gov (United States)

    Chen, Yang; Zou, Ling; Zhou, Bin

    2017-07-01

    The high mounting precision of the fiber underwater acoustic array leads to an array manifold without perturbation. Besides, the targets are either static or slowly moving in azimuth in underwater acoustic array signal processing. Therefore, the covariance matrix can be estimated accurately by prolonging the observation time. However, this processing is limited to poor bearing resolution due to small aperture, low SNR and strong interferences. In this paper, diagonal rejection (DR) technology for Minimum Variance Distortionless Response (MVDR) was developed to enhance the resolution performance. The core idea of DR is rejecting the main diagonal elements of the covariance matrix to improve the output signal to interference and noise ratio (SINR). The definition of SINR here implicitly assumes independence between the spatial filter and the received observations at which the SINR is measured. The power of noise converges on the diagonal line in the covariance matrix and then it is integrated into the output beams. With the diagonal noise rejected by a factor smaller than 1, the array weights of MVDR will concentrate on interference suppression, leading to a better resolution capability. The algorithm was theoretically proved with optimal rejecting coefficient derived under both infinite and finite snapshots scenarios. Numerical simulations were conducted with an example of a linear array with eight elements half-wavelength spaced. Both resolution and Direction-of-Arrival (DOA) performances of MVDR and DR-based MVDR (DR-MVDR) were compared under different SNR and snapshot numbers. A conclusion can be drawn that with the covariance matrix accurately estimated, DR-MVDR can provide a lower sidelobe output level and a better bearing resolution capacity than MVDR without harming the DOA performance.

  12. Models with orthogonal block structure, with diagonal blockwise variance-covariance matrices

    Science.gov (United States)

    Carvalho, Francisco; Mexia, João T.; Covas, Ricardo

    2017-07-01

    We intend to show that in the family of models with orthogonal block structure, OBS, we may single out those with blockwise diagonal variance-covariance matrices, DOBS. Namely we show that for every model with observation vector y with OBS, there is a model y °=P y , with P orthogonal which is DOBS and that the estimation of relevant parameters may be carried out for y ° .

  13. Generalized Coordinate Bethe Ansatz for open spin chains with non-diagonal boundaries

    CERN Document Server

    Ragoucy, E

    2011-01-01

    We introduce a generalization of the original Coordinate Bethe Ansatz that allows to treat the case of open spin chains with non-diagonal boundary matrices. We illustrate it on two cases: the XXX and XXZ chains. Short review on a joint work with N. Crampe (L2C) and D. Simon (LPMA), see arXiv:1009.4119, arXiv:1105.4119 and arXiv:1106.3264.

  14. Boundary form factors in the Smirnov--Fateev model with a diagonal boundary $S$ matrix

    CERN Document Server

    Lashkevich, Michael

    2008-01-01

    The boundary conditions with diagonal boundary $S$ matrix and the boundary form factors for the Smirnov--Fateev model on a half line has been considered in the framework of the free field representation. In contrast to the case of the sine-Gordon model, in this case the free field representation is shown to impose severe restrictions on the boundary $S$ matrix, so that a finite number of solutions is only consistent with the free field realization.

  15. Generalized Synchronization of Different Chaotic Systems Based on Nonnegative Off-Diagonal Structure

    Directory of Open Access Journals (Sweden)

    Ling Guo

    2013-01-01

    Full Text Available The generalized synchronization problem is studied in this paper for different chaotic systems with the aid of the direct design method. Based on Lyapunov stability theory and matrix theory, some sufficient conditions guaranteeing the stability of a nonlinear system with nonnegative off-diagonal structure are obtained. Then the control scheme is designed from the stable system by the direct design method. Finally, two numerical simulations are provided to verify the effectiveness and feasibility of the proposed method.

  16. Generalized cost-criterion-based learning algorithm for diagonal recurrent neural networks

    Science.gov (United States)

    Wang, Yongji; Wang, Hong

    2000-05-01

    A new generalized cost criterion based learning algorithm for diagonal recurrent neural networks is presented, which is with form of recursive prediction error (RPE) and has second convergent order. A guideline for the choice of the optimal learning rate is derived from convergence analysis. The application of this method to dynamic modeling of typical chemical processes shows that the generalized cost criterion RPE (QRPE) has higher modeling precision than BP trained MLP and quadratic cost criterion trained RPE (QRPE).

  17. Exact diagonalization of the D-dimensional spatially confined quantum harmonic oscillator

    Directory of Open Access Journals (Sweden)

    Kunle Adegoke

    2016-01-01

    Full Text Available In the existing literature various numerical techniques have been developed to quantize the confined harmonic oscillator in higher dimensions. In obtaining the energy eigenvalues, such methods often involve indirect approaches such as searching for the roots of hypergeometric functions or numerically solving a differential equation. In this paper, however, we derive an explicit matrix representation for the Hamiltonian of a confined quantum harmonic oscillator in higher dimensions, thus facilitating direct diagonalization.

  18. DIAGONALLY COMPENSATED REDUCTION AND MULTISPLITTING OF A SYMMETRIC POSITIVE DEFINITE MATRIX

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    To solve the symmetric positive definite linear system Ax = b on parallel and vector machines, multisplitting methods are considered. Here the s.p.d. (symmetric positive definite) matrix A need not be assumed in a special form (e.g. the dissection form [11]). The main tool for deriving our methods is the diagonally compensated reduction (cf. [1]). The convergence of such methods is also discussed by using this tool.

  19. Modeling animal-vehicle collisions using diagonal inflated bivariate Poisson regression.

    Science.gov (United States)

    Lao, Yunteng; Wu, Yao-Jan; Corey, Jonathan; Wang, Yinhai

    2011-01-01

    Two types of animal-vehicle collision (AVC) data are commonly adopted for AVC-related risk analysis research: reported AVC data and carcass removal data. One issue with these two data sets is that they were found to have significant discrepancies by previous studies. In order to model these two types of data together and provide a better understanding of highway AVCs, this study adopts a diagonal inflated bivariate Poisson regression method, an inflated version of bivariate Poisson regression model, to fit the reported AVC and carcass removal data sets collected in Washington State during 2002-2006. The diagonal inflated bivariate Poisson model not only can model paired data with correlation, but also handle under- or over-dispersed data sets as well. Compared with three other types of models, double Poisson, bivariate Poisson, and zero-inflated double Poisson, the diagonal inflated bivariate Poisson model demonstrates its capability of fitting two data sets with remarkable overlapping portions resulting from the same stochastic process. Therefore, the diagonal inflated bivariate Poisson model provides researchers a new approach to investigating AVCs from a different perspective involving the three distribution parameters (λ(1), λ(2) and λ(3)). The modeling results show the impacts of traffic elements, geometric design and geographic characteristics on the occurrences of both reported AVC and carcass removal data. It is found that the increase of some associated factors, such as speed limit, annual average daily traffic, and shoulder width, will increase the numbers of reported AVCs and carcass removals. Conversely, the presence of some geometric factors, such as rolling and mountainous terrain, will decrease the number of reported AVCs.

  20. The decoherence of quantum entanglement and teleportation in Bell-diagonal states

    Institute of Scientific and Technical Information of China (English)

    QIN Meng; LI Yan-Biao; WANG Xiao; BAI Zhong

    2012-01-01

    We study the dynamics of entanglement and teleportation in Bell-diagonal states. Using the concepts of concurrence and fidelity,the analytical expressions of the entanglement,the output entanglement and the average fidelity with decoherence are obtained for this model.We discover a class of initial states in which the output entanglement and the average fidelity are destroyed by decoherence. The quality of teleportation depends on the system parameters and time.

  1. Ligament balancing in total knee arthroplasty—Medial stabilizing technique

    Directory of Open Access Journals (Sweden)

    Shuichi Matsuda

    2015-10-01

    Full Text Available Ligament balancing is one of the most important surgical techniques for successful total knee arthroplasty. It has traditionally been recommended that medial and lateral as well as flexion and extension gaps are equal. This article reviews the relevant literature and discusses the clinical importance of the aforementioned gaps. Current evidence indicates that achieving medial stability throughout the range of motion should be a high priority in ligament balancing in total knee arthroplasty. Finally, the medial stabilising surgical technique, which aims to achieve good medial stability in posterior cruciate-retaining total knee arthroplasty, is introduced.

  2. Adaptive PVD Steganography Using Horizontal, Vertical, and Diagonal Edges in Six-Pixel Blocks

    Directory of Open Access Journals (Sweden)

    Anita Pradhan

    2017-01-01

    Full Text Available The traditional pixel value differencing (PVD steganographical schemes are easily detected by pixel difference histogram (PDH analysis. This problem could be addressed by adding two tricks: (i utilizing horizontal, vertical, and diagonal edges and (ii using adaptive quantization ranges. This paper presents an adaptive PVD technique using 6-pixel blocks. There are two variants. The proposed adaptive PVD for 2×3-pixel blocks is known as variant 1, and the proposed adaptive PVD for 3×2-pixel blocks is known as variant 2. For every block in variant 1, the four corner pixels are used to hide data bits using the middle column pixels for detecting the horizontal and diagonal edges. Similarly, for every block in variant 2, the four corner pixels are used to hide data bits using the middle row pixels for detecting the vertical and diagonal edges. The quantization ranges are adaptive and are calculated using the correlation of the two middle column/row pixels with the four corner pixels. The technique performs better as compared to the existing adaptive PVD techniques by possessing higher hiding capacity and lesser distortion. Furthermore, it has been proven that the PDH steganalysis and RS steganalysis cannot detect this proposed technique.

  3. Bending moment resistance of dowel corner joints in case-type furniture under diagonal compression load

    Institute of Scientific and Technical Information of China (English)

    Mosayeb Dalvand; Ghanbar Ebrahimi; Mehdi Tajvidi; Mohammad Layeghi

    2014-01-01

    We investigated bending moment resistance under diagonal compression load of corner doweled joints with plywood members. Joint members were made of 11-ply hardwood plywood of 19 mm thickness. Dowels were fabricated of Beech and Hornbeam species. Their diameters (6, 8 and 10 mm) and depths of penetration (9, 13 and 17 mm) in joint members were chosen variables in our experiment. By increasing the connector’s diameter from 6 to 8 mm, the bending moment resistance under diagonal compressive load was increased, while it decreased when the diameter was increased from 8 to 10 mm. The bending moment re-sistance under diagonal compressive load was increased by increasing the dowel’s depth of penetration. Joints made with dowels of Beech had higher resistance than dowels of Hornbeam. Highest resisting moment (45.18 N·m) was recorded for joints assembled with 8 mm Beech dowels penetrating 17 mm into joint members Lowest resisting moment (13.35 N·m) was recorded for joints assembled with 6 mm Hornbeam dowels and penetrating 9 mm into joint members.

  4. Thermalization away from integrability and the role of operator off-diagonal elements.

    Science.gov (United States)

    Konstantinidis, N P

    2015-05-01

    We investigate the rate of thermalization of local operators in the one-dimensional anisotropic antiferromagnetic Heisenberg model with next-nearest neighbor interactions that break integrability. This is done by calculating the scaling of the difference of the diagonal and canonical thermal ensemble values as a function of system size, and by directly calculating the time evolution of the expectation values of the operators with the Chebyshev polynomial expansion. Spatial and spin symmetry is exploited and the Hamiltonian is divided into subsectors according to their symmetry. The rate of thermalization depends on the proximity to the integrable limit. When integrability is weakly broken thermalization is slow, and becomes faster the stronger the next-nearest neighbor interaction is. Three different regimes for the rate of thermalization with respect to the strength of the integrability breaking parameter are identified. These are shown to be directly connected with the relative strength of the low and higher energy difference off-diagonal operator matrix elements in the symmetry eigenbasis of the Hamiltonian. Close to the integrable limit the off-diagonal matrix elements peak at higher energies and high-frequency fluctuations are important and slow down thermalization. Away from the integrable limit a strong low-energy peak gradually develops that takes over the higher frequency fluctuations and leads to quicker thermalization.

  5. Diagonal-free 3D/4D HN,HN-TROSY-NOESY-TROSY.

    Science.gov (United States)

    Diercks, Tammo; Truffault, Vincent; Coles, Murray; Millet, Oscar

    2010-02-24

    Structural biology by NMR spectroscopy relies on measuring interproton distances via NOE cross-signals in nuclear Overhauser effect spectroscopy (NOESY) spectra. In proteins, the subset of H(N)-H'(N) NOE contacts is most important for deriving initial structural models and for spectral assignment by "NOE walking". Here we present a fully optimized NMR experiment for measuring these pivotal contacts: diagonal-free 3D/4D HN,HN-TROSY-NOESY-TROSY. It combines all of the critical requirements for extracting the optimal H(N)-H'(N) distance information: the highest resolution by consistent transverse relaxation-optimized spectroscopy (TROSY) evolution, the largest spectral dispersion in two (15)N dimensions, and maximal coverage and purity through specific suppression of the intense diagonal signals that are the main source of overlap, artifacts, and bias in any NOESY spectrum. Most notably, diagonal suppression here comes without compromising the NOE cross-signal intensities. This optimized experiment appears to be ideal for a broad range of structural studies, particularly on large deuterated, partially unfolded, helical, and membrane proteins.

  6. Block-diagonal discriminant analysis and its bias-corrected rules.

    Science.gov (United States)

    Pang, Herbert; Tong, Tiejun; Ng, Michael

    2013-06-01

    High-throughput expression profiling allows simultaneous measure of tens of thousands of genes at once. These data have motivated the development of reliable biomarkers for disease subtypes identification and diagnosis. Many methods have been developed in the literature for analyzing these data, such as diagonal discriminant analysis, support vector machines, and k-nearest neighbor methods. The diagonal discriminant methods have been shown to perform well for high-dimensional data with small sample sizes. Despite its popularity, the independence assumption is unlikely to be true in practice. Recently, a gene module based linear discriminant analysis strategy has been proposed by utilizing the correlation among genes in discriminant analysis. However, the approach can be underpowered when the samples of the two classes are unbalanced. In this paper, we propose to correct the biases in the discriminant scores of block-diagonal discriminant analysis. In simulation studies, our proposed method outperforms other approaches in various settings. We also illustrate our proposed discriminant analysis method for analyzing microarray data studies.

  7. Medialized repair for retracted rotator cuff tears.

    Science.gov (United States)

    Kim, Young-Kyu; Jung, Kyu-Hak; Won, Jun-Sung; Cho, Seung-Hyun

    2017-08-01

    The purpose of this study was to evaluate the functional outcomes of medialized rotator cuff repair and the continuity of repaired tendon in chronic retracted rotator cuff tears. Thirty-five consecutive patients were selected from 153 cases that underwent arthroscopic rotator cuff repair for more than medium-sized posterosuperior rotator cuff tears between July 2009 and July 2012 performed with the medialized repair. All cases were available for at least 2 years of postoperative follow-up. The visual analog scale of pain, muscle strength, Constant score, American Shoulder and Elbow Surgeons (ASES) score, and University of California-Los Angeles score were evaluated. At the final follow-up, all clinical outcomes were significantly improved. The visual analog scale score for pain improved from 6 ± 1 preoperatively to 2 ± 1 postoperatively. The range of motion increased from preoperatively to postoperatively: active forward elevation, from 134° ± 49° to 150° ± 16°; active external rotation at the side, from 47° ± 15° to 55° ± 10°; and active internal rotation, from L3 to L1. The shoulder score also improved: Constant score, from 53.5 ± 16.7 to 79 ± 10; American Shoulder and Elbow Surgeons score, from 51 ± 15 to 82 ± 8; and University of California-Los Angeles score, from 14 ± 4 to 28 ± 4. The retear cases at the final follow-up were 6 (17%). Medialized repair may be useful in cases in which anatomic bone-to-tendon repair would be difficult because of the excessive tension of the repaired tendon and a torn tendon that does not reach the anatomic insertion. Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  8. Vibrational mode suppression in the non-Markovian limit : Diagonal time-gating of the stimulated photon echo

    NARCIS (Netherlands)

    De Boeij, W. P.; Pshenichnikov, M. S.; Wiersma, D. A.

    1996-01-01

    We demonstrate a novel technique for efficient vibrational mode suppression in stimulated photon echo by diagonal time-gating. This is especially important if the system exhibits non-Markovian optical dynamics.

  9. Revision Gore-Tex medialization laryngoplasty.

    Science.gov (United States)

    Cohen, Jacob T; Bates, Dwight D; Postma, Gregory N

    2004-09-01

    To evaluate the indications, results, and safety of revision Gore-Tex medialization laryngoplasty (GML). A retrospective chart review of 156 patients that underwent GML procedures between the years 1998-2002. Study population consisted of those patients who required revision surgery for any reason. Sixteen patients required 22 revision procedures. Indications for revision were divided into 2 groups, complications and glottal closure problems. Complications included extruded or displaced implants (n = 4). The most common glottal closure problem was undercorrection (n = 9). Others included anterior overcorrection (n = 1) and persistent posterior glottal gap (n = 2). Revision procedures included GML (n = 9), injection augmentation (n = 9), endoscopic implant removal (n = 2), and arytenoid adduction (n = 2). In patients with glottal closure problems, the GCI improved in all 10 and the voice rating scale improved in 9. Reasons for revision of GML are variable, the most common being undercorrection. A variety of safe, effective revision techniques are available with a high success rate.

  10. Neuromuscular Exercise Post Partial Medial Meniscectomy

    DEFF Research Database (Denmark)

    Hall, Michelle; Hinman, Rana S; Wrigley, Tim V

    2015-01-01

    outcomes included additional measures of knee joint load distribution, patient-reported outcomes, maximal knee and hip muscle strength, and physical function measures. RESULTS: 60 out of 62 randomized participants (97%) completed the trial. There were no significant between-group differences in the change......PURPOSE: To evaluate the effects of a 12-week, home-based, physiotherapist-guided neuromuscular exercise program on the knee adduction moment (an indicator of mediolateral knee load distribution) in people with a medial arthroscopic partial meniscectomy within the past 3-12 months. METHODS...... or a control group with no exercise. The exercise program included eight individual sessions with one of seven physiotherapists in private clinics, together with home exercises. Primary outcomes were the peak external knee adduction moment during normal pace walking and during a one-leg sit-to-stand. Secondary...

  11. Medial humeral epicondylitis in clinically affected cats.

    Science.gov (United States)

    Streubel, Ronny; Bilzer, Thomas; Grest, Paula; Damur, Daniel; Montavon, Pierre M

    2015-10-01

    To describe the clinical signs and histologic changes in cats clinically affected with medial humeral epicondylitis (MHE) and evaluate long-term outcome after either conservative or surgical treatment. Prospective cohort study. Client-owned cats (n = 17) with MHE. Cats diagnosed with MHE, based on clinical signs, radiographs and computed tomography (CT), were prospectively recruited. Cats were treated conservatively for an initial 4 weeks, followed by either surgery or continued conservative treatment. Followup examinations were performed at 6 and 12 weeks and at 6-49 months. Cats had a mean age of 10.3 years and presented for chronic lameness. Examination revealed pain on palpation caudodistal to the medial epicondyle and by exerting antebrachial supination/pronation with elbow and carpal flexion. Lameness was restricted to 1 limb although CT revealed bilateral disease in 11/17 cats. Free mineralized joint bodies were identified in 9/17 cats. Nine cats were treated surgically and 8 cats were treated conservatively. Intraoperative findings included new bone formation at the origin of the humeral head of the flexor carpi ulnaris muscle with displacement and adhesions of the ulnar nerve. Microscopic examination revealed neurogenic myopathy in 4/9 cats treated surgically. Seven of 9 cats treated surgically were free from lameness by 12 weeks. Seven of 8 cats treated conservatively were chronically lame throughout the study. Cats with forelimb lameness should be evaluated for MHE. This condition is associated with free joint bodies and neurogenic myopathy. Surgical treatment is associated with excellent outcome in the majority of cats. © Copyright 2015 by The American College of Veterinary Surgeons.

  12. Diagonal Matrix Elements of the Effective Hamiltonian for $K^{0}-\\bar{K}^{0} $ System in One Pole Approximation

    OpenAIRE

    Jankiewicz, Justyna

    2004-01-01

    We study the properties of time evolution of the $K^{0}-\\bar{K}^{0} $ system in spectral formulation. Within the one--pole model we find the exact form of the diagonal matrix elements of the effective Hamiltonian for this system. It appears that, contrary to the Lee--Oehme--Yang (LOY) result, these exact diagonal matrix elements are different if the total system is CPT--invariant but CP--noninvariant.

  13. Asymptotic correctability of Bell-diagonal qudit states and lower bounds on tolerable error probabilities in quantum cryptography

    CERN Document Server

    Ranade, K S; Alber, Gernot; Ranade, Kedar S.

    2007-01-01

    The concept of asymptotic correctability of Bell-diagonal quantum states is generalised to elementary quantum systems of higher dimensions. Based on these results basic properties of quantum state purification protocols are investigated which are capable of purifying tensor products of Bell-diagonal states and which are based on $B$-steps of the Gottesman-Lo-type with the subsequent application of a Calderbank-Shor-Steane quantum code. Consequences for maximum tolerable error rates of quantum cryptographic protocols are discussed.

  14. BCS Ground State and XXZ Antiferromagnetic Model as SU(2), SU(1,1) Coherent States: An Algebraic Diagonalization Method

    Institute of Scientific and Technical Information of China (English)

    XIE Bing-Hao; ZHANG Hong-Biao; CHEN Jing-Ling

    2002-01-01

    An algebraic diagonalization method is proposed. As two examples, the Hamiltonians of BCS ground stateunder mean-field approximation and XXZ antiferromagnetic model in linear spin-wave frame have been diagonalized byusing SU(2), SU(1,1) Lie algebraic method, respectively. Meanwhile, the eigenstates of the above two models are revealedto be SU(2), SU(1,1) coherent states, respectively. The relation between the usual Bogoliubov Valatin transformationand the algebraic method in a special case is also discussed.

  15. A New Upper Bound for A-1 of a Strictly α-Diagonally Dominant M-Matrix

    Directory of Open Access Journals (Sweden)

    Zhanshan Yang

    2013-01-01

    Full Text Available A new upper bound for A-1 of a real strictly diagonally dominant M-matrix A is present, and a new lower bound of the smallest eigenvalue λminA of A is given, which improved the results in the literature. Furthermore, an upper bound for A-1 of a real strictly α-diagonally dominant M-matrix is shown.

  16. Magnetic resonance imaging of AMS (Aneurysm of the Membranous Septum), review of the literature and case report.

    Science.gov (United States)

    Di Cesare, Ernesto; Di Sibio, Alessandra; Lanni, Giuseppe; Gennarelli, Antonio; Masciocchi, Carlo

    2014-05-01

    Aneurysm of the Membranous Septum (AMS) is a rare cardiac disease, mostly associated with other cardiac anomalies, very rare in the absence of other congenital heart defects. A prompt diagnosis is important, due to severe potential complications, but remain challenging. Most of the cases were earlier diagnosed using ventriculography, but, with the availability of echocardiography and cardiovascular magnetic resonance (CMR), this disease can be accurately assessed non-invasively. We report a case of a 62 years old female patient, without other cardiac congenital disease, who was incidentally diagnosed, by means of CMR with a true and isolated AMS. Our report underlines CMR usefulness in AMS diagnosis, thanks to accurate evaluation (both morphologic and functional) provided by this diagnostic tool, which is able to demonstrate clearly the presence of AMS (aneurysm of the membranous septum) and depict its features.

  17. A Rare Case of Primary Amenorrhea with Two Etiologies, Hypothalamic Amenorrhea, Transverse Vaginal Septum, and No Hematocolpos

    Directory of Open Access Journals (Sweden)

    Firouzeh Ghaffari

    2015-01-01

    Full Text Available We reported a rare case of hypothalamic amenorrhea and transverse vaginal septum. A 28-year-old woman presented with primary amenorrhea and no complaint of abdominal pain. Laparoscopy revealed a small rudimentary uterus with streak ovaries and a vaginal pouch. The patient with diagnosis of Mayer-Rokitansky-Kuster-Hauser (MRKH syndrome was subjected to a vaginoplasty in another fertility center. In our institute, after two courses of estrogen and progesterone, sonography revealed hematocolpos, while, under anesthesia, transverse vaginal septum was resected. Hysteroscopy revealed normal uterine cavity. She became pregnant 5 months postoperatively with controlled ovarian stimulation (COS in conjunction with intrauterine insemination, and she has two healthy babies now. This case highlights the importance of careful evaluation of all primary amenorrheas. Clinicians should be aware of presence of more than one etiology which causes atypical presentations and accomplishes a systematic strategy for the evaluation of amenorrhea potential to avoid long-term side effects of a misdiagnosis.

  18. Medial septal and median raphe innervation of vasoactive intestinal polypeptide-containing interneurons in the hippocampus.

    Science.gov (United States)

    Papp, E C; Hajos, N; Acsády, L; Freund, T F

    1999-05-01

    Vasoactive intestinal polypeptide-immunoreactive interneurons are known to form three anatomically and neurochemically well-characterized neuron populations in the hippocampus. Two of these establish synaptic contacts selectively with other GABAergic cells (interneuron-selective cells), whereas the third type innervates pyramidal cell bodies and proximal dendrites like a conventional basket cell. Our aim was to examine which of the vasoactive intestinal polypeptide-containing interneuron populations are among the targets of GABAergic septohippocampal and serotonergic raphe-hippocampal pathways. Anterograde tracing with Phaseolus vulgaris leucoagglutinin combined with double immunocytochemistry for vasoactive intestinal polypeptide was used at the light and electron microscopic levels. Our results show that both interneuron-selective cells and vasoactive intestinal polypeptide-containing basket cells receive synaptic input from the medial septum and median raphe nucleus. The GABAergic component of the septohippocampal pathway establishes multiple contacts on both cell types. In the case of the raphe-hippocampal projection, single or double contacts were more frequent on vasoactive intestinal polypeptide-positive interneuron selective cells (76%), whereas multiple contacts predominated on basket cells (83%). The extrinsic GABAergic innervation of interneuron-selective cells in the hippocampus indicates a complex interaction among GABAergic systems, which might ensure the timing and rhythmic synchronization of inhibitory processes in the hippocampus. On the other hand, our results suggest that the serotonergic effect on perisomatic inhibition is exerted via vasoactive intestinal polypeptide-containing basket cells that are functionally distinct from their parvalbumin-positive relatives, which appear to escape control of serotonergic as well as local interneuron-selective cells.

  19. Brain oxytocin in social fear conditioning and its extinction: involvement of the lateral septum.

    Science.gov (United States)

    Zoicas, Iulia; Slattery, David A; Neumann, Inga D

    2014-12-01

    Central oxytocin (OXT) has anxiolytic and pro-social properties both in humans and rodents, and has been proposed as a therapeutic option for anxiety and social dysfunctions. Here, we utilized a mouse model of social fear conditioning (SFC) to study the effects of OXT on social fear, and to determine whether SFC causes alterations in central OXT receptor (OXTR) binding and local OXT release. Central infusion of OXT, but not arginine vasopressin, prior to social fear extinction training completely abolished social fear expression in an OXTR-mediated fashion without affecting general anxiety or locomotion. SFC caused increased OXTR binding in the dorso-lateral septum (DLS), central amygdala, dentate gyrus, and cornu ammunis 1, which normalized after social fear extinction, suggesting that these areas form part of a brain network involved in the development and neural support of social fear. Microdialysis revealed that the increase in OXT release observed in unconditioned mice within the DLS during social fear extinction training was attenuated in conditioned mice. Consequently, increasing the availability of local OXT by infusion of OXT into the DLS reversed social fear. Thus, alterations in the brain OXT system, including altered OXTR binding and OXT release within the DLS, play an important role in SFC and social fear extinction. Thus, we suggest that the OXT system is adversely affected in disorders associated with social fear, such as social anxiety disorder and reinstalling an appropriate balance of the OXT system may alleviate some of the symptoms.

  20. Kindling of the lateral septum and the amygdala: effects on anxiety in rats.

    Science.gov (United States)

    Thomas, Earl; Gunton, Deborah J

    2011-10-24

    Long-term kindling of limbic system structures may produce substantial changes in emotional behavior in rats. This study examined long-term changes in two kindled structures that have opposite effects on anxiety, the lateral septum and the central nucleus of the amygdala. The purpose of the experiment was to examine the specificity of the emotional effects of kindling by employing a double dissociation design. Animals were tested in two common animal models of anxiety, the water-lick conflict test and the elevated plus-maze. In the conflict test amygdala-kindled animals demonstrated a significant anxiolytic effect when compared with sham-kindled animals. This effect was potentiated by chlordiazepoxide. Septally-kindled animals exhibited a significant anticonflict effect when compared to sham-kindled animals in the first session. Septally-kindled animals spent significantly more time on the open arms of the elevated plus-maze than did sham-kindled animals. Observed changes persisted 6weeks after the termination of 150 kindling sessions. The effects of long-term kindling were highly consistent with those of disruption rather than facilitation.

  1. Evidence of specialized tissue in human interatrial septum: histological, immunohistochemical and ultrastructural findings.

    Directory of Open Access Journals (Sweden)

    Lubov B Mitrofanova

    Full Text Available There is a paucity of information on structural organization of muscular bundles in the interatrial septum (IAS. The aim was to investigate histologic and ultrastructural organization of muscular bundles in human IAS, including fossa ovalis (FO and flap valve.Macroscopic and light microscopy evaluations of IAS were performed from postmortem studies of 40 patients. Twenty three IAS specimens underwent serial transverse sectioning, and 17--longitudinal sectioning. The transverse sections from 10 patients were immunolabeled for HCN4, Caveolin3 and Connexin43. IAS specimens from 6 other patients underwent electron microscopy.In all IAS specimens sections the FO, its rims and the flap valve had muscle fibers consisting of working cardiac myocytes. Besides the typical cardiomyocytes there were unusual cells: tortuous and horseshoe-shaped intertangled myocytes, small and large rounded myocytes with pale cytoplasm. The cells were aggregated in a definite structure in 38 (95% cases, which was surrounded by fibro-fatty tissue. The height of the structure on transverse sections positively correlated with age (P = 0.03 and AF history (P = 0.045. Immunohistochemistry showed positive staining of the cells for HCN4 and Caveolin3. Electron microscopy identified cells with characteristics similar to electrical conduction cells.Specialized conduction cells in human IAS have been identified, specifically in the FO and its flap valve. The cells are aggregated in a structure, which is surrounded by fibrous and fatty tissue. Further investigations are warranted to explore electrophysiological characteristics of this structure.

  2. A Novel Eddy Current Septum Magnet for SPS Extraction towards LHC and CNGS

    CERN Document Server

    Schröder, G H; Carlier, E; Dieperink, J H; Ducimetière, L; Goddard, B; Lázár, C; Mayer, M; Vossenberg, Eugène B; Weterings, W

    2000-01-01

    A new East Fast-Extraction System is under construction in the SPS, to supply particles with a maximum batch length of 7.8 us and 10.5 us to the LHC and to CNGS (CERN Neutrino to Gran Sasso), respectively. The extraction septum magnets actually used at the SPS have been designed for slow extraction over several seconds, have large cooling and electrical power demands and need frequently maintenance in a high radiation environment. A fast system of only 250 us pulse duration has therefore been developed, using a half-sine excitation pulse with a superimposed third harmonic. The short pulse duration requires very thin magnetic yoke laminations, which can not easily be stamped and stacked. Profiting from a development for the LHC beam dump kicker magnets, the yoke is therefore built-up from tape-wound cylindrical cores, employing 50 um thick Si-steel tape. Thirty two cores are stacked longitudinally to produce a yoke of 3.2 meter length. The aperture is cut radial into each cylinder. The cores are radial compres...

  3. Ulcerated calcification of the interventricular septum causing Transient Ischemic Attacks: Case Report

    Directory of Open Access Journals (Sweden)

    Economidis Stella

    2007-04-01

    Full Text Available Abstract Background Calcific deposits are frequently observed at sites of healed myocardial infarcts. Grossly visible calcification of myocardial infarcts and calcified intracavitary cardiac thrombi are less common but recently are becoming more frequent findings during surgical ventricular restoration procedures. Case Presentation A 64 years old male diabetic patient experienced two episodes of transient ischemic attacks during the last six months. During the diagnostic work up he was found to have triple vessel coronary artery disease with mild left ventricular dysfunction, akinesia of the anterior-apical wall and hypokinesia of the inferior wall. He was referred to our department for coronary artery bypass grafting. He underwent elective triple coronary artery bypass and a ventricular restoration procedure due to apical wall thinning. The inspection of the left ventricle revealed an ulcerated round shape calcification of the interventricular septum with a crater filled with clot. We resected the above lesion and covered the damaged area with the septal Dacron patch of the modified linear closure. The patient was discharged from the hospital on the 11th postoperative day and has been doing well 6 months later, with improvement in both ventricular function and clinical status. Conclusion The exploration of the left ventricular cavity reveals interesting phases of the post-infarction healing process. The suspicion of left ventricular thrombosis in patients with ventricular asynergy justifies a ventricular exploration during coronary artery bypass surgery.

  4. Control Loop for a Pulse Generator of a Fast Septum Magnet using DSP and Fuzzy Logic

    CERN Document Server

    Aldaz-Carroll, E; Dieperink, J H; Schröder, G; Vossenberg, Eugène B

    1997-01-01

    A prototype of a fast pulsed eddy current septum magnet for one of thebeam extraction's from the SPS towards LHC is under development. The precision of the magnetic field must be better than ±1.0 10-4 during a flat top of 30 µs. The current pulse is generated by discharging the capacitors of a LC circuit that resonates on the 1st and on the 3rd harmonic of a sine wave with a repetition rate of 15 s. The parameters of the circuit and the voltage on the capacitors must be carefully adjusted to meet the specifications. Drifts during operation must be corrected between two pulses by mechanically adjusting the inductance of the coil in the generator as well as the primary capacitor voltage. This adjustment process is automated by acquiring the current pulse waveform with sufficient time and amplitude resolution, calculating the corrections needed and applying these corrections to the hardware for the next pulse. A very cost-effective and practical solution for this adjustment process is the integration of off-th...

  5. Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats.

    Science.gov (United States)

    Zarrindast, Mohammad-Reza; Valizadegan, Farhad; Rostami, Parvin; Rezayof, Ameneh

    2008-03-31

    The central histaminergic system is known to have modulatory influence on anxiety-related behaviour both in animals and humans through histamine H1 and/or H2 receptors. In the present study, the effects of intra-lateral septal microinjections of histaminergic agents on anxiety-related behaviours in male Wistar rats have been investigated. As a model of anxiety, the elevated plus-maze which is a useful test to investigate the effects of anxiogenic or anxiolytic drugs in rodents was used. Intra-lateral septal administration of histamine (0.5 and 1 microg/rat) decreased the percentage of open arm entries and open arm time but not locomotor activity, showing an anxiogenic response. The intra-lateral septal injections of different doses of the histamine H1 receptor antagonist, pyrilamine (5, 10 and 20 microg/rat) or the histamine H2 receptor antagonist, ranitidine (5, 10 and 20 microg/rat) could not significantly alter the anxiety-like parameters in the plus-maze test. However, intra-lateral septal injections of different doses of pyrilamine (10 and 20 microg/rat) or ranitidine (10 and 20 microg/rat) significantly reversed histamine (1 microg/rat)-induced anxiogenic effect. The results may indicate that the histaminergic system of lateral septum modulate anxiety-like behaviour through histamine H1 and H2 receptors.

  6. Novel technique for injecting and extracting beams in a circular hadron accelerator without using septum magnets

    Directory of Open Access Journals (Sweden)

    Andrea Franchi

    2015-07-01

    Full Text Available With a few exceptions, all on-axis injection and extraction schemes implemented in circular particle accelerators, synchrotrons, and storage rings, make use of magnetic and electrostatic septa with systems of slow-pulsing dipoles acting on tens of thousands of turns and fast-pulsing dipoles on just a few. The dipoles create a closed orbit deformation around the septa, usually referred to as an orbit bump. A new approach is presented which obviates the need for the septum deflectors. Fast-pulsing elements are still required, but their strength can be minimized by choosing appropriate local accelerator optics. This technique should increase the beam clearance and reduce the usually high radiation levels found around the septa and also reduce the machine impedance introduced by the fast-pulsing dipoles. The basis of the technique is the creation of stable islands around stable fixed points in horizontal phase space. The trajectories of these islands may then be adjusted to match the position and angle of the incoming or outgoing beam.

  7. The effect of septoplasty on pulmonary artery pressure and right ventricular function in nasal septum deviation.

    Science.gov (United States)

    Ozkececi, Gulay; Akci, Onder; Bucak, Abdulkadir; Ulu, Sahin; Yalım, Zafer; Aycicek, Abdullah; Onrat, Ersel; Avsar, Alaettin

    2016-11-01

    Nasal septum deviation (NSD) can cause obstruction of the upper airway, which may lead to increased pulmonary artery pressure (PAP) and right ventricle dysfunction. The aim of the present study was to evaluate the effect of septoplasty on right ventricular function and mean PAP of patients with marked NSD. 25 patients with marked NSD (mean age = 31.8 ± 12.3 years) and 27 healthy volunteers (mean age = 34.5 ± 10.8 years) were enrolled. Echocardiography was performed for all subjects and right ventricular function and mean PAP were evaluated before and 3 months after septoplasty. Tricuspid annular plane systolic excursion (TAPSE) and tricuspid annulus early diastolic myocardial velocity (E') were significantly lower in patients with NSD than control subjects, while right ventricle myocardial performance index (RVMPI) and mean PAP were significantly higher (respectively, p = 0.006, 0.037, 0.049, 0.046). When preoperative and postoperative findings were compared, the mean PAP decreased whereas TAPSE increased significantly (respectively, p = 0.007, 0.03). The results of the present study demonstrated that mean PAP increased and right ventricular function worsened in patients with NSD. However, mean PAP decreased and right ventricular function tended to recover after septoplasty.

  8. Medial patellofemoral ligament and medial patellotibial ligament reconstruction in children: preliminary results.

    Science.gov (United States)

    Sadigursky, David; Garcia, Lucas Cortizo; Armede, Maurício; Oliveira, Lucas Rodrigues de; Carneiro, Rogério Jamil Fernandes; Colavolpe, Paulo Oliveira

    2017-01-01

    The aim of this study was to evaluate the reconstruction of the medial patellofemoral ligament associated with the medial patellotibial ligament in skeletally immature patients. This is a case series study in patients with patellar instability with open physis. In total, seven patients were evaluated: four males and three females were operated using the proposed technique. Patients with open physis who had more than two episodes of recurring patellar dislocation were included. No patients underwent additional procedures. The distance from the anterior tibial tuberosity to the trochlea grove (TT-TG) was measured in all patients. On physical examination, the inverted J-sign, the apprehension sign, and the knee range of motion parameters were used in the pre- and post-operative period. In addition, the Kujala and Lysholm scores were applied before and 12 months after surgery. The results were analyzed with the Wilcoxon test. The mean age of the patients was 11.28 in both genders. Comparing the data of the pre- and post-operative period, the inverted J-sign was present in six patients (85.7%) vs. absent in one (14.3%). The apprehension sign was absent in cases in the postoperative period; the range of motion was 117.85 ± 8.09 vs. 148.57 ± 3.77. The Kujala score was 42.57 ± 8.9 vs. 88.57 ± 5.09 and the Lysholm scores were classified as excellent or good in 28.6% and 71.4%, respectively. The combined reconstruction of the medial patellofemoral ligament combined with the medial patellotibial ligament in skeletally immature patients with predisposing factors, presents satisfactory results without episodes of recurrence or residual subluxation; according to these preliminary results, it should be considered as a treatment option.

  9. A Rare Case of Primary Amenorrhea with Two Etiologies, Hypothalamic Amenorrhea, Transverse Vaginal Septum, and No Hematocolpos

    OpenAIRE

    2015-01-01

    We reported a rare case of hypothalamic amenorrhea and transverse vaginal septum. A 28-year-old woman presented with primary amenorrhea and no complaint of abdominal pain. Laparoscopy revealed a small rudimentary uterus with streak ovaries and a vaginal pouch. The patient with diagnosis of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome was subjected to a vaginoplasty in another fertility center. In our institute, after two courses of estrogen and progesterone, sonography revealed hematocolpos...

  10. Quantitation of the regional blood flow in the interventricular septum using positron emission tomography and nitrogen-13 ammonia

    Energy Technology Data Exchange (ETDEWEB)

    Hove, Jens D. [The Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen (Denmark); Cardiovascular PET Research Unit, Section 9201, Medical Department B, The Heart Center, Rigshospitalet, Juliane Mariesvej 24, 2100 Copenhagen (Denmark); Gambhir, Sanjiv S. [Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, UCLA School of Medicine, Los Angeles, California (United States); Kofoed, Klaus F.; Freiberg, Jacob; Kelbaek, Henning [The Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen (Denmark)

    2003-01-01

    The purpose of the present study was to evaluate the effect of spillover of activity from the right ventricle (RV) on quantitation of the regional myocardial blood flow in the septum. Thirty-one healthy volunteers, 31 patients with ischemic heart disease, 7 patients with severe congestive heart failure, and 6 heart transplant patients underwent positron emission tomography (PET) with nitrogen-13 ammonia. Quantitation of the regional myocardial blood flow in the septum was performed using both a conventional two-compartment model and a previously validated two-compartment model taking RV spillover into account. Unaccounted RV spillover resulted in significant underestimation of the regional myocardial blood flow in the septum. The amount of underestimation was primarily dependent on the magnitude of spillover and the dispersion between the right and the left ventricular input functions. In healthy volunteers, the flow error was small but significant: on average 6% (range 5%-29%, P<0.00001), compared with 27% (range 0%-88%, P<0.002) in the group of patients with severe congestive heart failure, who had the most considerable amount of RV spillover. In the group of patients with ischemic heart disease and the group of heart transplant patients the flow errors were 10% (range 0%-55%, P<0.00001) and 6% (range 1%-19%, P<0.01), respectively. It is concluded that flow quantitation in the septum is significantly affected by RV spillover, resulting in a considerable underestimation of the septal blood flow unless correction is performed. (orig.)

  11. Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype.

    Science.gov (United States)

    Eisinger, Brian E; Driessen, Terri M; Zhao, Changjiu; Gammie, Stephen C

    2014-01-01

    The transition to motherhood involves CNS changes that modify sociability and affective state. However, these changes also put females at risk for post-partum depression and psychosis, which impairs parenting abilities and adversely affects children. Thus, changes in expression and interactions in a core subset of genes may be critical for emergence of a healthy maternal phenotype, but inappropriate changes of the same genes could put women at risk for post-partum disorders. This study evaluated microarray gene expression changes in medial prefrontal cortex (mPFC), a region implicated in both maternal behavior and psychiatric disorders. Post-partum mice were compared to virgin controls housed with females and isolated for identical durations. Using the Modular Single-set Enrichment Test (MSET), we found that the genetic landscape of maternal mPFC bears statistical similarity to gene databases associated with schizophrenia (5 of 5 sets) and bipolar disorder (BPD, 3 of 3 sets). In contrast to previous studies of maternal lateral septum (LS) and medial preoptic area (MPOA), enrichment of autism and depression-linked genes was not significant (2 of 9 sets, 0 of 4 sets). Among genes linked to multiple disorders were fatty acid binding protein 7 (Fabp7), glutamate metabotropic receptor 3 (Grm3), platelet derived growth factor, beta polypeptide (Pdgfrb), and nuclear receptor subfamily 1, group D, member 1 (Nr1d1). RT-qPCR confirmed these gene changes as well as FMS-like tyrosine kinase 1 (Flt1) and proenkephalin (Penk). Systems-level methods revealed involvement of developmental gene networks in establishing the maternal phenotype and indirectly suggested a role for numerous microRNAs and transcription factors in mediating expression changes. Together, this study suggests that a subset of genes involved in shaping the healthy maternal brain may also be dysregulated in mental health disorders and put females at risk for post-partum psychosis with aspects of schizophrenia

  12. Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype

    Directory of Open Access Journals (Sweden)

    Brian E Eisinger

    2014-04-01

    Full Text Available The transition to motherhood involves CNS changes that modify sociability and affective state. However, these changes also put females at risk for postpartum depression and psychosis, which impairs parenting abilities and adversely affects children. Thus, changes in expression and interactions in a core subset of genes may be critical for emergence of a healthy maternal phenotype, but inappropriate changes of the same genes could put women at risk for postpartum disorders. This study evaluated microarray gene expression changes in medial prefrontal cortex (mPFC, a region implicated in both maternal behavior and psychiatric disorders. Postpartum mice were compared to virgin controls housed with females and isolated for identical durations. Using the Modular Single-set Enrichment Test (MSET, we found that the genetic landscape of maternal mPFC bears statistical similarity to gene databases associated with schizophrenia (5 of 5 sets and bipolar disorder (BPD, 3 of 3 sets. In contrast to previous studies of maternal lateral septum and medial preoptic area, enrichment of autism and depression-linked genes was not significant (2 of 9 sets, 0 of 4 sets. Among genes linked to multiple disorders were fatty acid binding protein 7 (Fabp7, glutamate metabotropic receptor 3 (Grm3, platelet derived growth factor, beta polypeptide (Pdgfrb, and nuclear receptor subfamily 1, group D, member 1 (Nr1d1. RT-qPCR confirmed these gene changes as well as FMS-like tyrosine kinase 1 (Flt1 and proenkephalin (Penk. Systems-level methods revealed involvement of developmental gene networks in establishing the maternal phenotype and indirectly suggested a role for numerous microRNAs and transcription factors in mediating expression changes. Together, this study suggests that a subset of genes involved in shaping the healthy maternal brain may also be dysregulated in mental health disorders and put females at risk for postpartum psychosis with aspects of schizophrenia and BPD.

  13. Design of a Class of Antennas Utilizing MEMS, EBG and Septum Polarizers including Near-field Coupling Analysis

    Science.gov (United States)

    Kim, Ilkyu

    Recent developments in mobile communications have led to an increased appearance of short-range communications and high data-rate signal transmission. New technologies provides the need for an accurate near-field coupling analysis and novel antenna designs. An ability to effectively estimate the coupling within the near-field region is required to realize short-range communications. Currently, two common techniques that are applicable to the near-field coupling problem are 1) integral form of coupling formula and 2) generalized Friis formula. These formulas are investigated with an emphasis on straightforward calculation and accuracy for various distances between the two antennas. The coupling formulas are computed for a variety of antennas, and several antenna configurations are evaluated through full-wave simulation and indoor measurement in order to validate these techniques. In addition, this research aims to design multi-functional and high performance antennas based on MEMS (Microelectromechanical Systems) switches, EBG (Electromagnetic Bandgap) structures, and septum polarizers. A MEMS switch is incorporated into a slot loaded patch antenna to attain frequency reconfigurability. The resonant frequency of the patch antenna can be shifted using the MEM switch, which is actuated by the integrated bias networks. Furthermore, a high gain base-station antenna utilizing beam-tilting is designed to maximize gain for tilted beam applications. To realize this base-station antenna, an array of four dipole-EBG elements is constructed to implement a fixed down-tilt main beam with application in base station arrays. An improvement of the operating range with the EBG-dipole array is evaluated using a simple linkbudget analysis. The septum polarizer has been widely used in circularly polarized antenna systems due to its simple and compact design and high quality of circularity. In this research, the sigmoid function is used to smoothen the edge in the septum design, which

  14. Off-diagonal deformations of Kerr metrics and black ellipsoids in heterotic supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Vacaru, Sergiu I. [Quantum Gravity Research, Topanga, CA (United States); University ' ' Al. I. Cuza' ' , Project IDEI, Iasi (Romania); Irwin, Klee [Quantum Gravity Research, Topanga, CA (United States)

    2017-01-15

    Geometric methods for constructing exact solutions of equations of motion with first order α{sup '} corrections to the heterotic supergravity action implying a nontrivial Yang-Mills sector and six-dimensional, 6-d, almost-Kaehler internal spaces are studied. In 10-d spacetimes, general parametrizations for generic off-diagonal metrics, nonlinear and linear connections, and matter sources, when the equations of motion decouple in very general forms are considered. This allows us to construct a variety of exact solutions when the coefficients of fundamental geometric/physical objects depend on all higher-dimensional spacetime coordinates via corresponding classes of generating and integration functions, generalized effective sources and integration constants. Such generalized solutions are determined by generic off-diagonal metrics and nonlinear and/or linear connections; in particular, as configurations which are warped/compactified to lower dimensions and for Levi-Civita connections. The corresponding metrics can have (non-) Killing and/or Lie algebra symmetries and/or describe (1+2)-d and/or (1+3)-d domain wall configurations, with possible warping nearly almost-Kaehler manifolds, with gravitational and gauge instantons for nonlinear vacuum configurations and effective polarizations of cosmological and interaction constants encoding string gravity effects. A series of examples of exact solutions describing generic off-diagonal supergravity modifications to black hole/ellipsoid and solitonic configurations are provided and analyzed. We prove that it is possible to reproduce the Kerr and other type black solutions in general relativity (with certain types of string corrections) in the 4-d case and to generalize the solutions to non-vacuum configurations in (super-) gravity/string theories. (orig.)

  15. Fidelity of the diagonal ensemble signals the many-body localization transition

    Science.gov (United States)

    Hu, Taotao; Xue, Kang; Li, Xiaodan; Zhang, Yan; Ren, Hang

    2016-11-01

    In this work, we use exact matrix diagonalization to explore the many-body localization (MBL) transition in a random-field Heisenberg chain. We demonstrate that the fidelity and fidelity susceptibility can be utilized to characterize the interaction-driven many-body localization transition in this closed spin system which is in agreement with previous analytical and numerical results [S. Garnerone, N. T. Jacobson, S. Haas, and P. Zanardi, Phys. Rev. Lett. 102, 057205 (2009), 10.1103/PhysRevLett.102.057205; P. Zanardi and N. Paunkovic, Phys. Rev. E 74, 031123 (2006), 10.1103/PhysRevE.74.031123]. In particular, instead of ground-state fidelity, we test the fidelity between two diagonal ensembles related by a small parameter perturbation δ h , it is special that here the parameter perturbation δ hi for each site are random variables like hi. It shows that fidelity of the diagonal ensemble develop a pronounced drop at the transition. We utilize fidelity to estimate the critical disorder strength hc for different system size, we get hc∈ [2.5,3.9] and get a power-law decay with an exponent of roughly -1.49 (2 ) for system size N , and can extrapolate hcinf of the infinite system is about 2.07 which all agree with a recent work by Huse and Pal, in which the MBL transition in the same model was predicted to be hc [2,4]. We also estimate the scaling of maximum of averaged fidelity susceptibility as a function of system size N , it shows a power law increase with an exponent of about 5.05(1).

  16. Off-diagonal deformations of Kerr metrics and black ellipsoids in heterotic supergravity

    Science.gov (United States)

    Vacaru, Sergiu I.; Irwin, Klee

    2017-01-01

    Geometric methods for constructing exact solutions of equations of motion with first order α ^' } corrections to the heterotic supergravity action implying a nontrivial Yang-Mills sector and six-dimensional, 6-d, almost-Kähler internal spaces are studied. In 10-d spacetimes, general parametrizations for generic off-diagonal metrics, nonlinear and linear connections, and matter sources, when the equations of motion decouple in very general forms are considered. This allows us to construct a variety of exact solutions when the coefficients of fundamental geometric/physical objects depend on all higher-dimensional spacetime coordinates via corresponding classes of generating and integration functions, generalized effective sources and integration constants. Such generalized solutions are determined by generic off-diagonal metrics and nonlinear and/or linear connections; in particular, as configurations which are warped/compactified to lower dimensions and for Levi-Civita connections. The corresponding metrics can have (non-) Killing and/or Lie algebra symmetries and/or describe (1+2)-d and/or (1+3)-d domain wall configurations, with possible warping nearly almost-Kähler manifolds, with gravitational and gauge instantons for nonlinear vacuum configurations and effective polarizations of cosmological and interaction constants encoding string gravity effects. A series of examples of exact solutions describing generic off-diagonal supergravity modifications to black hole/ellipsoid and solitonic configurations are provided and analyzed. We prove that it is possible to reproduce the Kerr and other type black solutions in general relativity (with certain types of string corrections) in the 4-d case and to generalize the solutions to non-vacuum configurations in (super-) gravity/string theories.

  17. THE STRESS SUBSPACE OF HYBRID STRESS ELEMENT AND THE DIAGONALIZATION METHOD FOR FLEXIBILITY MATRIX H

    Institute of Scientific and Technical Information of China (English)

    张灿辉; 冯伟; 黄黔

    2002-01-01

    The following is proved: 1 ) The linear independence of assumed stress modes is the necessary and sufficient condition for the nonsingular fiexibility matrix; 2) The equivalent assumed stress modes lead to the identical hybrid element. The Hilbert stress subspace of the assumed stress modes is established. So, it is easy to derive the equivalent orthogonal normal stress modes by Schmidt 's method. Because of the resulting diagonal fiexibility matrix, the identical hybrid element is free from the complex matrix inversion so that the hybrid efficiency is improved greatly. The numerical examples show that the method is effective.

  18. Off-diagonal Bethe Ansatz solution of the $\\tau_2$-model

    CERN Document Server

    Xu, Xiaotian; Cui, Shuai; Yang, Wen-Li; Shi, Kangjie; Wang, Yupeng

    2015-01-01

    The generic quantum $\\tau_2$-model (also known as Baxter-Bazhanov-Stroganov (BBS) model) with periodic boundary condition is studied via the off-diagonal Bethe Ansatz method. The eigenvalues of the corresponding transfer matrix (solutions of the recursive functional relations in $\\tau_j$-hierarchy) with generic site-dependent inhomogeneity parameters are given in terms of an inhomogeneous T-Q relation with polynomial Q-functions. The associated Bethe Ansatz equations are obtained. Numerical solutions of the Bethe Ansatz equations for small number of sites indicate that the inhomogeneous T-Q relation does indeed give the complete spectrum.

  19. Feedback diagonal canonical form and its application to stabilization of nonlinear systems

    Institute of Scientific and Technical Information of China (English)

    CHENG Daizhan; HU Qingxi; QIN Huashu

    2005-01-01

    This paper considers the problem of stabilization of a class of nonlinear systems, which are possibly of non-minimum phase. A new feedback-equivalent canonical form, called diagonal normal form, of linear control systems is proposed. Using it, the corresponding normal form of affine nonlinear control systems is obtained. Based on this new normal form and the design technique of center manifold, a new constructing method for stabilizing control is presented. Certain examples are included to demonstrate the design strategy of stabilizers.

  20. Explicit Singly Diagonally Implicit Runge-Kutta Methods and Adaptive Stepsize Control for Reservoir Simulation

    DEFF Research Database (Denmark)

    Völcker, Carsten; Jørgensen, John Bagterp; Thomsen, Per Grove

    2010-01-01

    control applied to high order methods for temporal discretization in reservoir simulation. The family of Runge-Kutta methods is presented and in particular the explicit singly diagonally implicit Runge-Kutta (ESDIRK) method with an embedded error estimate is described. A predictive stepsize adjustment...... rule based on error estimates and convergence control of the integrated iterative solver is presented. We try to improve the predictive stepsize control through an extended communication between the convergence rate, the error control and the stepsize. Keywords: Reservoir simulation, implicit Runge-Kutta...

  1. Magnetic Dispersion of the Diagonal Incommensurate Phase in Lightly Doped La2

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, M. [Japan Atomic Energy Agency (JAEA); Fujita, M. [Tohoku University, Japan; Wakimoto, S [Japan Atomic Energy Agency (JAEA); Fernandez-Baca, Jaime A [ORNL; Tranquada, John M. [Brookhaven National Laboratory (BNL); Yamada, K. [Tohoku University, Japan

    2008-01-01

    We present inelastic neutron scattering experiments on a single-domain crystal of lightly doped La1:96Sr0:04CuO4. We find that the magnetic excitation spectrum in this insulating phase with a diagonal incommensurate spin modulation is remarkably similar to that in the superconducting regime, where the spin modulation is bond parallel. In particular, we find that the dispersion slope at low energy is essentially independent of doping and temperature over a significant range. The energy at which the excitations cross the commensurate antiferromagnetic wave vector increases roughly linearly with doping through the underdoped regime.

  2. Self-Calibration of Radio Astronomical Arrays With Non-Diagonal Noise Covariance Matrix

    CERN Document Server

    Wijnholds, Stefan J

    2010-01-01

    The radio astronomy community is currently building a number of phased array telescopes. The calibration of these telescopes is hampered by the fact that covariances of signals from closely spaced antennas are sensitive to noise coupling and to variations in sky brightness on large spatial scales. These effects are difficult and computationally expensive to model. We propose to model them phenomenologically using a non-diagonal noise covariance matrix. The parameters can be estimated using a weighted alternating least squares (WALS) algorithm iterating between the calibration parameters and the additive nuisance parameters. We demonstrate the effectiveness of our method using data from the low frequency array (LOFAR) prototype station.

  3. Diagonal Based Feature Extraction for Handwritten Alphabets Recognition System using Neural Network

    CERN Document Server

    Pradeep, J; Himavathi, S; 10.5121/ijcsit.2011.3103

    2011-01-01

    An off-line handwritten alphabetical character recognition system using multilayer feed forward neural network is described in the paper. A new method, called, diagonal based feature extraction is introduced for extracting the features of the handwritten alphabets. Fifty data sets, each containing 26 alphabets written by various people, are used for training the neural network and 570 different handwritten alphabetical characters are used for testing. The proposed recognition system performs quite well yielding higher levels of recognition accuracy compared to the systems employing the conventional horizontal and vertical methods of feature extraction. This system will be suitable for converting handwritten documents into structural text form and recognizing handwritten names.

  4. Off-diagonal Bethe Ansatz solution of the τ{sub 2}-model

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Xiaotian [Institute of Modern Physics, Northwest University,Xian 710069 (China); Cao, Junpeng [Beijing National Laboratory for Condensed Matter Physics,Institute of Physics, Chinese Academy of Sciences,Beijing 100190 (China); Collaborative Innovation Center of Quantum Matter,Beijing (China); Cui, Shuai [Beijing National Laboratory for Condensed Matter Physics,Institute of Physics, Chinese Academy of Sciences,Beijing 100190 (China); Yang, Wen-Li [Institute of Modern Physics, Northwest University,Xian 710069 (China); Beijing Center for Mathematics and Information Interdisciplinary Sciences,Beijing 100048 (China); Shi, Kangjie [Institute of Modern Physics, Northwest University,Xian 710069 (China); Wang, Yupeng [Beijing National Laboratory for Condensed Matter Physics,Institute of Physics, Chinese Academy of Sciences,Beijing 100190 (China); Collaborative Innovation Center of Quantum Matter,Beijing (China)

    2015-09-30

    The generic quantum τ{sub 2}-model (also known as Baxter-Bazhanov-Stroganov (BBS) model) with periodic boundary condition is studied via the off-diagonal Bethe Ansatz method. The eigenvalues of the corresponding transfer matrix (solutions of the recursive functional relations in τ{sub j}-hierarchy) with generic site-dependent inhomogeneity parameters are given in terms of an inhomogeneous T−Q relation with polynomial Q-functions. The associated Bethe Ansatz equations are obtained. Numerical solutions of the Bethe Ansatz equations for small number of sites indicate that the inhomogeneous T−Q relation does indeed give the complete spectrum.

  5. Diagonalization-free implementation of spin relaxation theory for large spin systems

    CERN Document Server

    Kuprov, Ilya

    2010-01-01

    The Liouville space spin relaxation theory equations are reformulated in such a way as to avoid the computationally expensive Hamiltonian diagonalization step, replacing it by numerical evaluation of the integrals in the generalized cumulant expansion. The resulting algorithm is particularly useful in the cases where the static part of the Ha-miltonian is dominated by interactions other than Zeeman (e.g. in quadrupolar reson-ance, low-field EPR and Spin Chemistry). When used together with state space re-striction tools, the algorithm reported is capable of computing full relaxation supero-perators for NMR systems with more than 15 spins.

  6. Numerical Investigation on the Separated Flow of Axial Flow Stator in Diagonal Flow Fan

    Science.gov (United States)

    Kinoue, Yoichi; Shiomi, Norimasa; Setoguchi, Toshiaki; Kaneko, Kenji; Jin, Yingzi

    2010-06-01

    Experimental and numerical investigations were conducted for the internal flow of the stator of the diagonal flow fan. Corner separation near the hub surface and the suction surface of the stator blade are focused on. At low flow rate of 80% of the design flow rate, the corner separation between the suction surface and the hub surface can be found in both experimental and numerical results. Separation vortices are found in the computed oil flow on both suction and hub surfaces at 80% of the design flow rate in the three-dimensional numerical simulation.

  7. Ship motion extreme short time prediction of ship pitch based on diagonal recurrent neural network

    Institute of Scientific and Technical Information of China (English)

    SHEN Yan; XIE Mei-ping

    2005-01-01

    A DRNN (diagonal recurrent neural network) and its RPE (recurrent prediction error) learning algorithm are proposed in this paper .Using of the simple structure of DRNN can reduce the capacity of calculation. The principle of RPE learning algorithm is to adjust weights along the direction of Gauss-Newton. Meanwhile, it is unnecessary to calculate the second local derivative and the inverse matrixes, whose unbiasedness is proved. With application to the extremely short time prediction of large ship pitch, satisfactory results are obtained. Prediction effect of this algorithm is compared with that of auto-regression and periodical diagram method, and comparison results show that the proposed algorithm is feasible.

  8. Design and analysis of a novel chaotic diagonal recurrent neural network

    Science.gov (United States)

    Wang, Libiao; Meng, Zhuo; Sun, Yize; Guo, Lei; Zhou, Mingxing

    2015-09-01

    A chaotic neural network model with logistic mapping is proposed to improve the performance of the conventional diagonal recurrent neural network. The network shows rich dynamic behaviors that contribute to escaping from a local minimum to reach the global minimum easily. Then, a simple parameter modulated chaos controller is adopted to enhance convergence speed of the network. Furthermore, an adaptive learning algorithm with the robust adaptive dead zone vector is designed to improve the generalization performance of the network, and weights convergence for the network with the adaptive dead zone vectors is proved in the sense of Lyapunov functions. Finally, the numerical simulation is carried out to demonstrate the correctness of the theory.

  9. CONVERGENCE OF PARALLEL DIAGONAL ITERATION OF RUNGE-KUTTA METHODS FOR DELAY DIFFERENTIAL EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    Xiao-hua Ding; Mingzhu Liu

    2004-01-01

    Implicit Runge-Kutta method is highly accurate and stable for stiff initial value prob-lem. But the iteration technique used to solve implicit Runge-Kutta method requires lots of computational efforts. In this paper, we extend the Parallel Diagonal Iterated Runge-Kutta(PDIRK) methods to delay differential equations(DDEs). We give the convergence region of PDIRK methods, and analyze the speed of convergence in three parts for the P-stability region of the Runge-Kutta corrector method. Finally, we analysis the speed-up factor through a numerical experiment. The results show that the PDIRK methods to DDEs are efficient.

  10. On the topological complexity and the homotopy cofibre of the diagonal map

    CERN Document Server

    Calcines, J

    2011-01-01

    In this paper we analyze some relationships between the topological complexity of a space $X$ and the category of $C_{\\Delta_X},$ the homotopy cofibre of the diagonal map $\\Delta_X:X\\rightarrow X\\times X.$ As a consequence of this work and of a result by M. Farber, S. Tabachnikov and S. Yuzvinsky, we obtain that the immersion problem for the real projective space $\\RP^n$ is equivalent to the computation of the L.-S. category of $C_{\\Delta_{\\RP^n}}.$

  11. First Diagonal Coronary Artery: Left Ventricular Fistula Presenting as Unstable Angina

    Directory of Open Access Journals (Sweden)

    Murat Sener

    2013-01-01

    Full Text Available Coronary artery fistulae are characterized by communications between a coronary artery and a cardiac chamber or another vascular structure. They are usually congenital, but acquired forms may occur. Most patients are usually asymptomatic. However, some studies have emphasized that the incidence of symptoms and complications increases with age, particularly after the age of 20 (Liberthson et al. 1979, Hong et al. 2004. We aimed to present a very rare form of fistula originating from the first diagonal artery and connecting into the left ventricle.

  12. First diagonal coronary artery: left ventricular fistula presenting as unstable angina.

    Science.gov (United States)

    Sener, Murat; Akkaya, Mehmet; Bilici, Muammer

    2013-01-01

    Coronary artery fistulae are characterized by communications between a coronary artery and a cardiac chamber or another vascular structure. They are usually congenital, but acquired forms may occur. Most patients are usually asymptomatic. However, some studies have emphasized that the incidence of symptoms and complications increases with age, particularly after the age of 20 (Liberthson et al. 1979, Hong et al. 2004). We aimed to present a very rare form of fistula originating from the first diagonal artery and connecting into the left ventricle.

  13. Subspace-Based Noise Reduction for Speech Signals via Diagonal and Triangular Matrix Decompositions

    DEFF Research Database (Denmark)

    Hansen, Per Christian; Jensen, Søren Holdt

    2007-01-01

    We survey the definitions and use of rank-revealing matrix decompositions in single-channel noise reduction algorithms for speech signals. Our algorithms are based on the rank-reduction paradigm and, in particular, signal subspace techniques. The focus is on practical working algorithms, using both...... diagonal (eigenvalue and singular value) decompositions and rank-revealing triangular decompositions (ULV, URV, VSV, ULLV and ULLIV). In addition we show how the subspace-based algorithms can be evaluated and compared by means of simple FIR filter interpretations. The algorithms are illustrated...... with working Matlab code and applications in speech processing....

  14. The medial scaffold of 3D unorganized point clouds.

    Science.gov (United States)

    Leymarie, Frederic F; Kimia, Benjamin B

    2007-02-01

    We introduce the notion of the medial scaffold, a hierarchical organization of the medial axis of a 3D shape in the form of a graph constructed from special medial curves connecting special medial points. A key advantage of the scaffold is that it captures the qualitative aspects of shape in a hierarchical and tightly condensed representation. We propose an efficient and exact method for computing the medial scaffold based on a notion of propagation along the scaffold itself, starting from initial sources of the flow and constructing the scaffold during the propagation. We examine this method specifically in the context of an unorganized cloud of points in 3D, e.g., as obtained from laser range finders, which typically involve hundreds of thousands of points, but the ideas are generalizable to data arising from geometrically described surface patches. The computational bottleneck in the propagation-based scheme is in finding the initial sources of the flow. We thus present several ideas to avoid the unnecessary consideration of pairs of points which cannot possibly form a medial point source, such as the "visibility" of a point from another given a third point and the interaction of clusters of points. An application of using the medial scaffold for the representation of point samplings of real-life objects is also illustrated.

  15. [Left ventricular synchrony with septum stimulation vs. septal ventricular outflow tract in complete atrioventricular block].

    Science.gov (United States)

    Rodríguez-Serrano, Gustavo; Lara-Vaca, Susano; Pereyra-Nobara, Texar; Bernal-Ruiz, Enrique

    2016-01-01

    Introducción: el objetivo del presente estudio fue determinar si existe diferencia en la función sistólica y la sincronía del ventrículo izquierdo con estimulación del septum medio o tracto de salida del ventrículo derecho en pacientes con bloqueo auriculoventricular portadores de marcapaso. Métodos: estudio observacional, analítico, transversal. Se seleccionaron todos los pacientes mayores de 18 años portadores de marcapaso con diagnóstico de bloqueo auriculoventricular. Se analizaron dos grupos acorde al sitio de colocación del electrodo de estimulación en región septal media o tracto de salida del ventrículo derecho. Se determinó la fracción de expulsión y sincronía del ventrículo izquierdo. Resultados: se incluyeron 54 pacientes por cada grupo, siendo las características de ambos similares, excepto el tiempo de colocación del electrodo de estimulación ventricular (p = < 0.001). No hubo diferencia significativa en la fracción de expulsión o sincronía del ventrículo izquierdo. Conclusiones: no se encontró diferencia en la fracción de expulsión o sincronía del ventrículo izquierdo independientemente del sitio de colocación del electrodo de estimulación.

  16. Morphology of tricuspid valve in pulmonary atresia with intact ventricular septum.

    Science.gov (United States)

    Choi, Y H; Seo, J W; Choi, J Y; Yun, Y S; Kim, S H; Lee, H J

    1998-01-01

    Pulmonary atresia with intact ventricular septum (PAIVS) is a rare congenital cardiac anomaly that has been classified into two types: one is a more frequent type having dysplasia of tricuspid valve (TV) with a small annulus, underdeveloped right ventricle (RV) with a hypoplastic cavity and a hypertrophic wall; the other type has severe dysplasia of TV and dilatation of RV, right atrium (RA), and right atrioventricular junction with thinning of the RV wall. We performed a morphologic study on 11 autopsied hearts with PAIVS, giving particular emphasis to the variation of morphology of the TV. We could classify these hearts into 3 groups according to the degree of right ventricular development. In the first group of 7 cases (type I), the RVs were underdeveloped. Thick leaflets, restricted valve apparatus with short chordae, and small annuli were characteristics of the TV. In the second group of 3 cases (type II), the RVs showed marked enlargement of the cavity and thinning of the wall. The TV showed redundant, dysplastic, sail-like anterior leaflets, and the downward displacement of septal leaflet and/or posterior leaflet, which are the findings frequently observed in Ebstein's malformation. The RVs were dilated and with partially unguarded tricuspid orifice. The septal leaflet of the TV was dysplastic and, in two cases, the septal leaflet showed chordal structure at the upper surface facing the RA, which is a peculiar finding that has not been described in the literature. The remaining case was a heart with a moderately developed RV (type III). The TV showed mildly dysplastic appearance and we classify this as a separate type, because we could expect the best surgical results in this type. This type had optimal size of RV and the mildest degree of dysplasia of TV. In PAIVS, the morphology of TV correlates well with the type of the right ventricular development.

  17. Evolution of the management approach for pulmonary atresia with intact ventricular septum

    Science.gov (United States)

    Mi, Y P; Chau, A K T; Chiu, C S W; Yung, T C; Lun, K S; Cheung, Y F

    2005-01-01

    Objective: To review the evolution of the management approach for pulmonary atresia with intact ventricular septum (PAIVS) in the past two decades and to assess its impact on patient outcomes. Design and patients: Retrospective review of the management and outcomes of 94 patients (55 male patients) with PAIVS diagnosed between July 1980 and August 2003. Settings: Tertiary paediatric cardiac centre. Results: Seven patients died before interventions. Of the remaining 87 patients who underwent intervention at a median age of 9 days (from 1 day to 2 years), 12 had right ventricular outflow tract reconstruction (RVOTR), 42 had closed pulmonary valvotomy (CPV), and 15 had laser assisted valvotomy with balloon valvoplasty. A systemic–pulmonary shunt was inserted in 18 patients, six of whom had subsequent RVOTR (n  =  4) or laser assisted valvotomy (n  =  2). Since 1990, catheter intervention accounted for 38% (17 of 45) of the right ventricular outflow procedures. The mean (SEM) freedom from reintervention was 93 (7)%, 71 (12)%, and 57 (13)% after RVOTR, 75 (7)%, 40 (8)%, and 14 (6)% after CPV, and 54 (13)%, 24 (12)%, and 16 (10)% after laser assisted valvotomy at one month, six months, and one year, respectively (RVOTR versus CPV, p < 0.001; RVOTR versus laser assisted valvotomy, p  =  0.001). Low cardiac output syndrome was significantly less common after catheter intervention than after RVOTR (0% v 44%, p  =  0.003) or CPV (0% v 29%, p  =  0.01). The overall mean (SEM) survival was 77 (5)% and 70 (5)% at one and five years, respectively, and the overall mortality was 33% (29 of 87). There were no significant differences in survival between the three groups. Conclusions: Multiple interventions are often required in the treatment algorithm of PAIVS. The shift towards increased use of the transcatheter approach has reduced the occurrence of postprocedural low cardiac output syndrome. PMID:15831657

  18. Optogenetic dissection of medial prefrontal cortex circuitry

    Directory of Open Access Journals (Sweden)

    Danai eRiga

    2014-12-01

    Full Text Available The medial prefrontal cortex (mPFC is critically involved in numerous cognitive functions, including attention, inhibitory control, habit formation, working memory and long-term memory. Moreover, through its dense interconnectivity with subcortical regions (e.g. thalamus, striatum, amygdala and hippocampus, the mPFC is thought to exert top-down executive control over the processing of aversive and appetitive stimuli. Because the mPFC has been implicated in the processing of a wide range of cognitive and emotional stimuli, it is thought to function as a central hub in the brain circuitry mediating symptoms of psychiatric disorders. New optogenetics technology enables anatomical and functional dissection of mPFC circuitry with unprecedented spatial and temporal resolution. This provides important novel insights in the contribution of specific neuronal subpopulations and their connectivity to mPFC function in health and disease states. In this review, we present the current knowledge obtained with optogenetic methods concerning mPFC function and dysfunction and integrate this with findings from traditional intervention approaches used to investigate the mPFC circuitry in animal models of cognitive processing and psychiatric disorders.

  19. Optogenetic dissection of medial prefrontal cortex circuitry.

    Science.gov (United States)

    Riga, Danai; Matos, Mariana R; Glas, Annet; Smit, August B; Spijker, Sabine; Van den Oever, Michel C

    2014-01-01

    The medial prefrontal cortex (mPFC) is critically involved in numerous cognitive functions, including attention, inhibitory control, habit formation, working memory and long-term memory. Moreover, through its dense interconnectivity with subcortical regions (e.g., thalamus, striatum, amygdala and hippocampus), the mPFC is thought to exert top-down executive control over the processing of aversive and appetitive stimuli. Because the mPFC has been implicated in the processing of a wide range of cognitive and emotional stimuli, it is thought to function as a central hub in the brain circuitry mediating symptoms of psychiatric disorders. New optogenetics technology enables anatomical and functional dissection of mPFC circuitry with unprecedented spatial and temporal resolution. This provides important novel insights in the contribution of specific neuronal subpopulations and their connectivity to mPFC function in health and disease states. In this review, we present the current knowledge obtained with optogenetic methods concerning mPFC function and dysfunction and integrate this with findings from traditional intervention approaches used to investigate the mPFC circuitry in animal models of cognitive processing and psychiatric disorders.

  20. Medial plica after reconstruction of anterior cruciate ligament

    Institute of Scientific and Technical Information of China (English)

    YIN Yu; WANG Jian-quan; HE Zhen-ming

    2009-01-01

    Background The medial plica may be caused by direct trauma or joint degeneration,which also could be iatrogenic.There have been few reports in the literature discussing incidence of the medial plica caused by an operation on the knee joint,specifically after the reconstruction of anterior cruciate ligament (ACL).In this study,we aimed to evaluate and analyze the relationship between the incidence of the medial plica and reconstruction of the ACL.Methods A retrospective case series study was conducted to review the findings of 1085 patients between 2003 and 2007,who underwent second-look arthroscopy after reconstruction of the ACL (between 2002 and 2006).The correlation of the incidence of medial plica with the stability of the knee joint,the time from onset of injury to reconstruction surgery,the associated injuries,and the rate of progress during postoperative rehabilitation were analyzed.Results We found that 722 patients had the structure of a medial plica.The incidence after reconstruction of the anterior cruciate ligament (66.5%) was significantly higher than usually reported.All these medial plica had avascular fibrotic and thickened edges.An excision of pathologic medial plica and fat pad synovial fringes were done.The incidences were significantly different between the two groups with their reconstruction operation time,from onset of injury to surgery (less than one month or over 2 years),and the progress rate of postoperative rehabilitation (knee flexion could not be over 90° in four weeks).The incidence was not different between the groups with knee stable conditions.Conclusions Medial plica is more common in patients after reconstruction of ACL.More associated injuries and more rehabilitation difficulties can increase the medial plica incidence.

  1. Medial Femoral Condyle Degeneration Associated with a Mediopatellar Plica

    Directory of Open Access Journals (Sweden)

    Mehmet Balik

    2014-03-01

    Full Text Available Sixty-years-old female patient complaining from knee pain since 15 years. The patient could not localize the pain at first. Since 10 years, she experiences a temporary pain localized at the medial side of tibiofemoral joint during twisting her knee. Also, pain persists at the medial patellar region at semi-flexed position of her knee. The patient did not benefit from conversative treatment with the diagnosis of gonarthrosis. We performed knee artrhroplasty. During arthroplasty, we observed that the medial femoral condyle was damaged due to long term mediopatellar plica impingement.

  2. Seismic Behavior of Steel Off-Diagonal Bracing System (ODBS Utilized in Reinforced Concrete Frame

    Directory of Open Access Journals (Sweden)

    Keyvan Ramin

    2014-01-01

    Full Text Available The introduction of an eccentricity in this system results in a geometric nonlinearity behavior. The midpoint of the diagonal member is connected to the corner joint using a brace member with a relatively low stiffness, thus forming a three-member bracing system in each braced panel. An iterative method of analysis has been developed to study the nonlinear load-deflection behavior of ODBS. The results indicate that the load-deflection behavior of this system follows a nonlinear stiffness-hardening pattern with two yielding points, which reflect the tensile failure of different bracings; the present study aims to investigate the efficiency of applying off-diagonal steel braces to reinforced concrete frames. To achieve this, three types of 2-story, 6-story, and 15-story structures without and with X-bracing and off-center bracing systems were modeled using SAP2000 software, and for micromodeling ANSYS software was used to achieve finite element results for an exact comparison between various retrofitting systems. The results showed that the structures strengthened by toggle bracing system revealed better behavior for low oscillation periods. Moreover, this type of bracing system is quite suitable for 10-story structures but not for higher ones. Its main problem, which requires special contrivances to solve, is the existence of a soft ground floor.

  3. Randomly Generating Four Mixed Bell-Diagonal States with a Concurrences Sum to Unity

    Institute of Scientific and Technical Information of China (English)

    S. P. Toh; Hishamuddin Zainuddin; Kim Eng Foo

    2012-01-01

    A two-qubit system in quantum information theory is the simplest bipartite quantum system and its concurrence for pure and mixed states is well known. As a subset of two-qubit systems, Bell-diagonal states can be depicted by a very simple geometrical representation of a tetrahedron with sides of length 2√2. Based on this geometric representation, we propose a simple approach to randomly generate four mixed Bell decomposable states in which the sum of their concurrence is equal to one.%A two-qubit system in quantum information theory is the simplest bipartite quantum system and its concurrence for pure and mixed states is well known.As a subset of two-qubit systems,Bell-diagonal states can be depicted by a very simple geometrical representation of a tetrahedron with sides of length 2(√2).Based on this geometric representation,we propose a simple approach to randomly generate four mixed Bell decomposable states in which the sum of their concurrence is equal to one.

  4. IMPACTS OF DIFFERENT JOINT ANGLES AND ADHESIVES ON DIAGONAL TENSION PERFORMANCES OF BOX-TYPE FURNITURE

    Directory of Open Access Journals (Sweden)

    Musa Atar

    2010-02-01

    Full Text Available The goal of this study was to determine the effects of different joint angles and adhesives on diagonal tension performances of the box-type furniture made from solid wood and medium density fiberboard (MDF. After drilling joints of 75º, 78º, 81º, 84º, and 87º degrees on Oriental beech, European oak, Scotch pine, and MDF samples, a diagonal tensile test was applied on corners glued with polyvinyl acetate (PVAc and polyurethane (D-VTKA = Desmodur-Vinyl Trieketonol Acetate according to ASTM D 1037 standard. With reference to the obtained results, the highest tensile strength was obtained in European oak with PVAc glue and joint angle of 84º, while the lowest value was obtained in MDF with D-VTKA glue and joint angle of 75º. Considering the interaction of wood, adhesive, and joint angle, the highest tensile strength was obtained in European oak with joint angle of 81º and D-VTKA glue (1.089 N.mm-2, whereas the lowest tensile strength was determined in MDF with joint angle of 75º and PVAc glue (0.163 N.mm-2. Therefore, PVAc as glue and 81º as joint angle could be suggested to obtain some advantageous on the dovetail joint process for box-type furniture made from both solid wood and MDF.

  5. On the inclusion of the diagonal Born-Oppenheimer correction in surface hopping methods

    CERN Document Server

    Gherib, Rami; Ryabinkin, Ilya G; Izmaylov, Artur F

    2016-01-01

    The diagonal Born-Oppenheimer correction (DBOC) stems from the diagonal second derivative coupling term in the adiabatic representation, and it can have an arbitrary large magnitude when a gap between neighbouring Born-Oppenheimer (BO) potential energy surfaces (PESs) is closing. Nevertheless, DBOC is typically neglected in mixed quantum-classical methods of simulating nonadiabatic dynamics (e.g., fewest-switch surface hopping (FSSH) method). A straightforward addition of DBOC to BO PESs in the FSSH method, FSSH+D, has been shown to lead to numerically much inferior results for models containing conical intersections. More sophisticated variation of the DBOC inclusion, phase-space surface-hopping (PSSH) was more successful than FSSH+D but on model problems without conical intersections. This work comprehensively assesses the role of DBOC in nonadiabatic dynamics of two electronic state problems and the performance of FSSH, FSSH+D, and PSSH methods in variety of one- and two-dimensional models. Our results sho...

  6. Kondo physics of the Anderson impurity model by distributional exact diagonalization

    Science.gov (United States)

    Motahari, S.; Requist, R.; Jacob, D.

    2016-12-01

    The distributional exact diagonalization (DED) scheme is applied to the description of Kondo physics in the Anderson impurity model. DED maps Anderson's problem of an interacting impurity level coupled to an infinite bath onto an ensemble of finite Anderson models, each of which can be solved by exact diagonalization. An approximation to the self-energy of the original infinite model is then obtained from the ensemble-averaged self-energy. Using Friedel's sum rule, we show that the particle number constraint, a central ingredient of the DED scheme, ultimately imposes Fermi liquid behavior on the ensemble-averaged self-energy, and thus is essential for the description of Kondo physics within DED. Using the numerical renormalization group (NRG) method as a benchmark, we show that DED yields excellent spectra, both inside and outside the Kondo regime for a moderate number of bath sites. Only for very strong correlations (U /Γ ≫10 ) does the number of bath sites needed to achieve good quantitative agreement become too large to be computationally feasible.

  7. Selecting protein N-terminal peptides by combined fractional diagonal chromatography.

    Science.gov (United States)

    Staes, An; Impens, Francis; Van Damme, Petra; Ruttens, Bart; Goethals, Marc; Demol, Hans; Timmerman, Evy; Vandekerckhove, Joël; Gevaert, Kris

    2011-07-14

    In recent years, procedures for selecting the N-terminal peptides of proteins with analysis by mass spectrometry have been established to characterize protease-mediated cleavage and protein α-N-acetylation on a proteomic level. As a pioneering technology, N-terminal combined fractional diagonal chromatography (COFRADIC) has been used in numerous studies in which these protein modifications were investigated. Derivatization of primary amines--which can include stable isotope labeling--occurs before trypsin digestion so that cleavage occurs after arginine residues. Strong cation exchange (SCX) chromatography results in the removal of most of the internal peptides. Diagonal, reversed-phase peptide chromatography, in which the two runs are separated by reaction with 2,4,6-trinitrobenzenesulfonic acid, results in the removal of the C-terminal peptides and remaining internal peptides and the fractionation of the sample. We describe here the fully matured N-terminal COFRADIC protocol as it is currently routinely used, including the most substantial improvements (including treatment with glutamine cyclotransferase and pyroglutamyl aminopeptidase to remove pyroglutamate before SCX, and a sample pooling scheme to reduce the overall number of liquid chromatography-tandem mass spectrometry analyses) that were made since its original publication. Completion of the N-terminal COFRADIC procedure takes ~5 d.

  8. A combined joint diagonalization-MUSIC algorithm for subsurface targets localization

    Science.gov (United States)

    Wang, Yinlin; Sigman, John B.; Barrowes, Benjamin E.; O'Neill, Kevin; Shubitidze, Fridon

    2014-06-01

    This paper presents a combined joint diagonalization (JD) and multiple signal classification (MUSIC) algorithm for estimating subsurface objects locations from electromagnetic induction (EMI) sensor data, without solving ill-posed inverse-scattering problems. JD is a numerical technique that finds the common eigenvectors that diagonalize a set of multistatic response (MSR) matrices measured by a time-domain EMI sensor. Eigenvalues from targets of interest (TOI) can be then distinguished automatically from noise-related eigenvalues. Filtering is also carried out in JD to improve the signal-to-noise ratio (SNR) of the data. The MUSIC algorithm utilizes the orthogonality between the signal and noise subspaces in the MSR matrix, which can be separated with information provided by JD. An array of theoreticallycalculated Green's functions are then projected onto the noise subspace, and the location of the target is estimated by the minimum of the projection owing to the orthogonality. This combined method is applied to data from the Time-Domain Electromagnetic Multisensor Towed Array Detection System (TEMTADS). Examples of TEMTADS test stand data and field data collected at Spencer Range, Tennessee are analyzed and presented. Results indicate that due to its noniterative mechanism, the method can be executed fast enough to provide real-time estimation of objects' locations in the field.

  9. Forces and mechanical energy fluctuations during diagonal stride roller skiing; running on wheels?

    Science.gov (United States)

    Kehler, Alyse L; Hajkova, Eliska; Holmberg, Hans-Christer; Kram, Rodger

    2014-11-01

    Mechanical energy can be conserved during terrestrial locomotion in two ways: the inverted pendulum mechanism for walking and the spring-mass mechanism for running. Here, we investigated whether diagonal stride cross-country roller skiing (DIA) utilizes similar mechanisms. Based on previous studies, we hypothesized that running and DIA would share similar phase relationships and magnitudes of kinetic energy (KE), and gravitational potential energy (GPE) fluctuations, indicating elastic energy storage and return, as if roller skiing is like 'running on wheels'. Experienced skiers (N=9) walked and ran at 1.25 and 3 m s(-1), respectively, and roller skied with DIA at both speeds on a level dual-belt treadmill that recorded perpendicular and parallel forces. We calculated the KE and GPE of the center of mass from the force recordings. As expected, the KE and GPE fluctuated with an out-of-phase pattern during walking and an in-phase pattern during running. Unlike walking, during DIA, the KE and GPE fluctuations were in phase, as they are in running. However, during the glide phase, KE was dissipated as frictional heat and could not be stored elastically in the tendons, as in running. Elastic energy storage and return epitomize running and thus we reject our hypothesis. Diagonal stride cross-country skiing is a biomechanically unique movement that only superficially resembles walking or running.

  10. Counting spanning trees of the hypercube and its $q$-analogs by explicit block diagonalization

    CERN Document Server

    Srinivasan, Murali K

    2011-01-01

    The number of spanning trees of a graph $G$ is called the {\\em complexity} of $G$ and is denoted $c(G)$. Let C(n) denote the {\\em (binary) hypercube} of dimension $n$. A classical result in enumerative combinatorics (based on explicit diagonalization) states that $c(C(n)) = \\prod_{k=2}^n (2k)^{n\\choose k}$. In this paper we use the explicit block diagonalization methodology to derive formulas for the complexity of two $q$-analogs of C(n), the {\\em nonbinary hypercube} $\\Cq(n)$, defined for $q\\geq 2$, and the {\\em vector space analog of the hypercube} $\\Cfq(n)$, defined for prime powers $q$. We consider the nonbinary and vector space analogs of the Boolean algebra. We show the existence, in both cases, of a graded Jordan basis (with respect to the up operator) that is orthogonal (with respect to the standard inner product) and we write down explicit formulas for the ratio of the lengths of the successive vectors in the Jordan chains (i.e., the singular values). With respect to (the normalizations of) these bas...

  11. Modified dynamical supergravity breaking and off-diagonal super-Higgs effects

    Science.gov (United States)

    Gheorghiu, Tamara; Vacaru, Olivia; Vacaru, Sergiu

    2015-03-01

    We argue that generic off-diagonal vacuum and nonvacuum solutions for Einstein manifolds mimic physical effects in modified gravity theories (MGTs) and encode certain models of the f(R,T,\\ldots ), Hořava type with dynamical Lorentz symmetry breaking, induced effective mass for the graviton, etc. Our main goal is to investigate the dynamical breaking of local supersymmetry determined by off-diagonal solutions in MGTs and encoded as effective Einstein spaces. This includes the Deser-Zumino super-Higgs effect, for instance, for a one-loop potential in a simple but representative model of N=1,D=4 supergravity. We develop and apply new geometrical techniques that allow us to decouple the gravitational field equations and integrate them in a very general form with the metric and vielbein fields depending on all the spacetime coordinates by means of various generating and integration functions and parameters. We study how solutions in MGTs may be related to the dynamical generation of a gravitino mass and supersymmetry breaking.

  12. Modified Dynamical Supergravity Breaking and Off-Diagonal Super-Higgs Effects

    CERN Document Server

    Gheorghiu, Tamara; Vacaru, Sergiu

    2015-01-01

    We argue that generic off-diagonal vacuum and nonvacuum solutions for Einstein manifolds mimic physical effects in modified gravity theories (MGTs) and encode certain models of $f(R,T,...)$, Ho\\vrava type with dynamical Lorentz symmetry breaking, induced effective mass for graviton etc. Our main goal is to investigate the dynamical breaking of local supersymmetry determined by off--diagonal solutions in MGTs encoded as effective Einstein spaces. This includes the Deser-Zumino super--Higgs effect, for instance, for an one--loop potential in a (simple but representative) model of $\\mathcal{N}=1, D=4$ supergravity. We develop and apply a new geometric techniques which allows us to decouple the gravitational field equations and integrate them in very general forms with metrics and vierbein fields depending on all spacetime coordinates via various generating and integration functions and parameters. We study how solutions in MGTs may be related to dynamical generation of a gravitino mass and supergravity breaking.

  13. The effects of skiing velocity on mechanical aspects of diagonal cross-country skiing.

    Science.gov (United States)

    Andersson, Erik; Pellegrini, Barbara; Sandbakk, Oyvind; Stüggl, Thomas; Holmberg, Hans-Christer

    2014-09-01

    Cycle and force characteristics were examined in 11 elite male cross-country skiers using the diagonal stride technique while skiing uphill (7.5°) on snow at moderate (3.5 ± 0.3 m/s), high (4.5 ± 0.4 m/s), and maximal (5.6 ± 0.6 m/s) velocities. Video analysis (50 Hz) was combined with plantar (leg) force (100 Hz), pole force (1,500 Hz), and photocell measurements. Both cycle rate and cycle length increased from moderate to high velocity, while cycle rate increased and cycle length decreased at maximal compared to high velocity. The kick time decreased 26% from moderate to maximal velocity, reaching 0.14 s at maximal. The relative kick and gliding times were only altered at maximal velocity, where these were longer and shorter, respectively. The rate of force development increased with higher velocity. At maximal velocity, sprint-specialists were 14% faster than distance-specialists due to greater cycle rate, peak leg force, and rate of leg force development. In conclusion, large peak leg forces were applied rapidly across all velocities and the shorter relative gliding and longer relative kick phases at maximal velocity allow maintenance of kick duration for force generation. These results emphasise the importance of rapid leg force generation in diagonal skiing.

  14. Thermoelectric behavior of conducting polymers: On the possibility of off-diagonal thermoelectricity

    Energy Technology Data Exchange (ETDEWEB)

    Mateeva, N.; Testardi, L. [TecOne, Inc., Tallahassee, FL (United States); Niculescu, H. [TecOne, Inc., Tallahassee, FL (United States)]|[Florida A and M Univ./Florida State Univ., Tallahassee, FL (United States) Coll. of Engineering; Schlenoff, J. [TecOne, Inc., Tallahassee, FL (United States)]|[Florida State Univ., Tallahassee, FL (United States). Chemistry Dept.

    1998-12-01

    Non-cubic materials, when structurally aligned, possess sufficient anisotropy to exhibit thermoelectric effects where the electrical and thermal paths can be orthogonal due to off-diagonal thermoelectricity (ODTE). The authors discuss the benefits of this form of thermoelectricity for device applications and describe a search for suitable thermoelectric properties in the air-stable conducting polymers polyaniline and polypyrrole. They find, at 300K for diagonal (ordinary) thermoelectricity (DTE), the general correlation that the logarithm of the electrical conductivity varies linearly with the Seebeck coefficient on doping, but with a proportionality in excess of a prediction from theory. The correlation is unexpected in its universality and unfavorable in its consequences for applications in DTE and ODTE. A standard model suggests that conduction by carriers of both signs occurs in these polymers, which thus leads to reduced thermoelectric efficiency. They also discuss polyacetylene (which is not air-stable), where this ambipolar conduction does not occur, and where properties seem more favorable for thermoelectricity.

  15. Shrinkage-based diagonal Hotelling’s tests for high-dimensional small sample size data

    KAUST Repository

    Dong, Kai

    2015-09-16

    DNA sequencing techniques bring novel tools and also statistical challenges to genetic research. In addition to detecting differentially expressed genes, testing the significance of gene sets or pathway analysis has been recognized as an equally important problem. Owing to the “large pp small nn” paradigm, the traditional Hotelling’s T2T2 test suffers from the singularity problem and therefore is not valid in this setting. In this paper, we propose a shrinkage-based diagonal Hotelling’s test for both one-sample and two-sample cases. We also suggest several different ways to derive the approximate null distribution under different scenarios of pp and nn for our proposed shrinkage-based test. Simulation studies show that the proposed method performs comparably to existing competitors when nn is moderate or large, but it is better when nn is small. In addition, we analyze four gene expression data sets and they demonstrate the advantage of our proposed shrinkage-based diagonal Hotelling’s test.

  16. Fraction-free algorithm for the computation of diagonal forms matrices over Ore domains using Gr{\\"o}bner bases

    CERN Document Server

    Levandovskyy, Viktor

    2011-01-01

    This paper is a sequel to "Computing diagonal form and Jacobson normal form of a matrix using Groebner bases", J. of Symb. Computation, 46 (5), 2011. We present a new fraction-free algorithm for the computation of a diagonal form of a matrix over a certain non-commutative Euclidean domain over a computable field with the help of Gr\\"obner bases. This algorithm is formulated in a general constructive framework of non-commutative Ore localizations of $G$-algebras (OLGAs). We split the computation of a normal form of a matrix into the diagonalization and the normalization processes. Both of them can be made fraction-free. For a matrix $M$ over an OLGA we provide a diagonalization algorithm to compute $U,V$ and $D$ with fraction-free entries such that $UMV=D$ holds and $D$ is diagonal. The fraction-free approach gives us more information on the system of linear functional equations and its solutions, than the classical setup of an operator algebra with rational functions coefficients. In particular, one can handl...

  17. 变系数模型的稳健估计%Entanglement of Tripartite Bell Diagonal States

    Institute of Scientific and Technical Information of China (English)

    赵培信; 薛留根

    2011-01-01

    为了研究变系数模型的稳健估计问题,结合B-样条方法和taut string方法得到了一个稳健估计过程;结合局部二次逼近方法,给出了一个迭代算法.数据模拟结果表明所得估计是稳健的.%A necessary condition of entanglement for tripartite 2 (⊕)2 (⊕)3 Bell diagonal states and a sufficient condition of entanglement for 3 (⊕)3 (⊕)3 Bell diagonal states are presented. Moreover, the relation between entanglement of 3(⊕)3(⊕)3 Bell diagonal states and partial transpose of density matrix is investigated. And an analytical expression of negative for Bell diagonal states is presented.Key words: Bell diagonal states; entanglement; density matrix Robust Estimation for Varying Coefficient Model Abstract: This paper considers robust estimation of varying coefficient models with emphasis on resistance against outliers. By combining B-splines method with taut string method, a robust estimation procedure is proposed. Based on local quadratic approximation, an iterative algorithm is introduced. Simulation study indicates that the proposed method is robust.

  18. Medial tibial stress syndrome: a critical review.

    Science.gov (United States)

    Moen, Maarten H; Tol, Johannes L; Weir, Adam; Steunebrink, Miriam; De Winter, Theodorus C

    2009-01-01

    Medial tibial stress syndrome (MTSS) is one of the most common leg injuries in athletes and soldiers. The incidence of MTSS is reported as being between 4% and 35% in military personnel and athletes. The name given to this condition refers to pain on the posteromedial tibial border during exercise, with pain on palpation of the tibia over a length of at least 5 cm. Histological studies fail to provide evidence that MTSS is caused by periostitis as a result of traction. It is caused by bony resorption that outpaces bone formation of the tibial cortex. Evidence for this overloaded adaptation of the cortex is found in several studies describing MTSS findings on bone scan, magnetic resonance imaging (MRI), high-resolution computed tomography (CT) scan and dual energy x-ray absorptiometry. The diagnosis is made based on physical examination, although only one study has been conducted on this subject. Additional imaging such as bone, CT and MRI scans has been well studied but is of limited value. The prevalence of abnormal findings in asymptomatic subjects means that results should be interpreted with caution. Excessive pronation of the foot while standing and female sex were found to be intrinsic risk factors in multiple prospective studies. Other intrinsic risk factors found in single prospective studies are higher body mass index, greater internal and external ranges of hip motion, and calf girth. Previous history of MTSS was shown to be an extrinsic risk factor. The treatment of MTSS has been examined in three randomized controlled studies. In these studies rest is equal to any intervention. The use of neoprene or semi-rigid orthotics may help prevent MTSS, as evidenced by two large prospective studies.

  19. Medial temporal lobe and topographical memory.

    Science.gov (United States)

    Urgolites, Zhisen J; Hopkins, Ramona O; Squire, Larry R

    2017-08-08

    There has been interest in the idea that medial temporal lobe (MTL) structures might be especially important for spatial processing and spatial memory. We tested the proposal that the MTL has a specific role in topographical memory as assessed in tasks of scene memory where the viewpoint shifts from study to test. Building on materials used previously for such studies, we administered three different tasks in a total of nine conditions. Participants studied a scene depicting four hills of different shapes and sizes and made a choice among four test images. In the Rotation task, the correct choice depicted the study scene from a shifted perspective. MTL patients succeeded when the study and test images were presented together but failed the moment the study scene was removed (even at a 0-s delay). In the No-Rotation task, the correct choice was a duplicate of the study scene. Patients were impaired to the same extent in the No-Rotation and Rotation tasks after matching for difficulty. Thus, an inability to accommodate changes in viewpoint does not account for patient impairment. In the Nonspatial-Perceptual task, the correct choice depicted the same overall coloring as the study scene. Patients were intact at a 2-s delay but failed at longer, distraction-filled delays. The different results for the spatial and nonspatial tasks are discussed in terms of differences in demand on working memory. We suggest that the difficulty of the spatial tasks rests on the neocortex and on the limitations of working memory, not on the MTL.

  20. Variant attachments of the anterior horn of the medial meniscus.

    Science.gov (United States)

    Jakubowicz, Marian; Ratajczak, Wojciech; Pytel, Andrzej

    2003-01-01

    The purpose of this study was to analyse the occurrence of variants of anomalous insertions of the anterior horn of the medial meniscus in human knee joints. The study was carried out on 78 human lower limbs of both sexes (42 males and 36 females). Out of 78 knee joints, 10 knee joints (12.82%) presented atypical attachments of the anterior horn of the medial meniscus. In 9 cases we found that the anterior horn of the medial meniscus was attached to the transverse ligament of the knee and in 1 case it was attached to the coronary ligament. In the remaining cases the anterior horn of the medial meniscus was attached to the anterior intercondylar area of the tibia.

  1. Medial Meniscus Posterior Root Tear: A Comprehensive Review

    National Research Council Canada - National Science Library

    Lee, Dhong Won; Ha, Jeong Ku; Kim, Jin Goo

    2014-01-01

    Damage to the medial meniscus root, for example by a complete radial tear, destroys the ability of the knee to withstand hoop strain, resulting in contact pressure increases and kinematic alterations...

  2. Hyperglycemia decreased medial amygdala projections to medial preoptic area in experimental model of Diabetes Mellitus.

    Directory of Open Access Journals (Sweden)

    Yousef Mohamadi

    2015-01-01

    Full Text Available In Wistar rats, reproductive behavior is controlled in a neural circuit of ventral forebrain including the medial amygdala (Me, bed nucleus of the stria terminalis (BNST and medial preoptic area (MPOA via perception of social odors. Diabetes Mellitus (DM is a widespread metabolic disease that affects many organs in a variety of levels. DM can cause central neuropathies such as neuronal apoptosis, dendritic atrophy, neurochemical alterations and also causes reproductive dysfunctions. So we hypothesized damage to the nuclei of this circuit can cause reproductive dysfunctions. Therefore in this project we assessed diabetic effect on these nuclei. For this purpose neuron tracing technique and TUNEL assay were used. We injected HRP in the MPOA and counted labeled cells in the Me and BNST to evaluate the reduction of neurons in diabetic animals. Also, coronal sections were analyzed with the TMB histochemistry method. Animals in this study were adult male Wistar rats (230 ± 8g divided to control and 10-week streptozotocin-induced diabetic groups. After data analysis by SPSS 16 software, a significant reduction of HRP-labeled neurons was shown in both Me and BNST nuclei in the diabetic group. Moreover, apoptotic cells were significantly observed in diabetic animals in contrast to control the group. In conclusion, these alterations of the circuit as a result of diabetes might be one of the reasons for reproductive dysfunctions.

  3. Medial rectus muscle anchoring in complete oculomotor nerve palsy.

    Science.gov (United States)

    Lee, Si Hyung; Chang, Jee Ho

    2015-10-01

    The management of exotropia resulting from complete oculomotor nerve palsy is challenging. Conventional therapeutic interventions, including supramaximal resection and recession, superior oblique tendon resection and transposition, and several ocular anchoring procedures have yielded less-than-adequate results. Here we describe a novel surgical technique of anchoring the medial rectus muscle to the medial orbital wall in combination with lateral rectus disinsertion and reattachment to the lateral orbital wall.

  4. Electrophysiological and autoradiographical evidence of V1 vasopressin receptors in the lateral septum of the rat brain

    Energy Technology Data Exchange (ETDEWEB)

    Raggenbass, M.; Tribollet, E.; Dreifuss, J.J.

    1987-11-01

    Extracellular recordings were obtained from single neurons located in the lateral septum, an area known to receive a vasopressinergic innervation in the rat brain. Approximately half of the neurons tested responded to 8-L-arginine vasopressin (AVP) by a marked increase in firing rate at concentrations greater than 1 nM. The effect of vasopressin was blocked by synthetic structural analogues possessing antagonistic properties on peripheral vasopressin and oxytocin receptors. Oxytocin was much less potent than vasopressin in firing septal neurons, and a selective oxytocic agonist was totally ineffective. The action of vasopressin on neuronal firing was mimicked by the vasopressor agonist (2-phenylalanine,8-ornithine)vasotocin but not by the selective antidiuretic agonist 1-deamino(8-D-arginine)vasopressin. In a parallel study, sites that bind (/sup 3/H)AVP at low concentration (1.5 nM) were found by in vitro autoradiography in the lateral septum. Adjacent sections were also incubated with 1.5 mM (/sup 3/H)AVP and, in addition, with 100 nM (2-phenylalanine,8-ornithine)vasotocin or 1-deamino(8-D-arginine)vasopressin--i.e., the same compounds as those used for the electrophysiological study. Results showed that the vasopressor agonist, but not the antidiuretic agonist, displaced (/sup 3/H)AVP, thus indicating that the vasopressin binding sites detected by autoradiography in the septum were V1 (vasopressor type) rather than V2 (antidiuretic type) receptors. Based on the electrophysiological evidence, we conclude that these receptors, when occupied, lead to increased firing of lateral septal neurons.

  5. Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.

    Science.gov (United States)

    Henssen, Anton; Zilles, Karl; Palomero-Gallagher, Nicola; Schleicher, Axel; Mohlberg, Hartmut; Gerboga, Fatma; Eickhoff, Simon B; Bludau, Sebastian; Amunts, Katrin

    2016-02-01

    Previous architectonical studies of human orbitofrontal cortex (OFC) provided divergent maps regarding number, location, and extent of areas. To solve this controversy, an observer-independent cytoarchitectonical mapping of medial OFC (mOFC) was performed. Borders of cortical areas were detected in histological sections of ten human post-mortem brains using a quantitative, statistically testable method, and their stereotaxic localization and intersubject variability were determined. Three areas were identified: granular Fo1 mainly on the rostral Gyrus rectus and medial of the olfactory sulcus; granular to dysgranular Fo2, mainly on the posterior part of the ventromedial Gyrus rectus and the medial and lateral banks of the olfactory sulcus; granular Fo3 between the olfactory and medial or intermediate orbital sulci. Fo3 was bordered medially by Fo1 and Fo2 and laterally by the lateral OFC (lOFC). A cluster analysis of the cytoarchitectonical features of Fo1-Fo3, subgenual cingulate areas, BA12, lateral and medial areas of the frontopolar cortex, lOFC and areas of Broca's region demonstrated the cytoarchitectonical similarity between the mOFC areas in contrast to all other frontal areas. Probabilistic maps of mOFC areas show a considerable intersubject variability in extent and position in stereotaxic space, and provide spatial templates for anatomical localization of in vivo neuroimaging data via the JuBrain atlas and the Anatomy Toolbox.

  6. Comparative cephalopod shell strength and the role of septum morphology on stress distribution

    Directory of Open Access Journals (Sweden)

    Robert Lemanis

    2016-09-01

    Full Text Available The evolution of complexly folded septa in ammonoids has long been a controversial topic. Explanations of the function of these folded septa can be divided into physiological and mechanical hypotheses with the mechanical functions tending to find widespread support. The complexity of the cephalopod shell has made it difficult to directly test the mechanical properties of these structures without oversimplification of the septal morphology or extraction of a small sub-domain. However, the power of modern finite element analysis now permits direct testing of mechanical hypothesis on complete, empirical models of the shells taken from computed tomographic data. Here we compare, for the first time using empirical models, the capability of the shells of extant Nautilus pompilius, Spirula spirula, and the extinct ammonite Cadoceras sp. to withstand hydrostatic pressure and point loads. Results show hydrostatic pressure imparts highest stress on the final septum with the rest of the shell showing minimal compression. S. spirula shows the lowest stress under hydrostatic pressure while N. pompilius shows the highest stress. Cadoceras sp. shows the development of high stress along the attachment of the septal saddles with the shell wall. Stress due to point loads decreases when the point force is directed along the suture as opposed to the unsupported chamber wall. Cadoceras sp. shows the greatest decrease in stress between the point loads compared to all other models. Greater amplitude of septal flutes corresponds with greater stress due to hydrostatic pressure; however, greater amplitude decreases the stress magnitude of point loads directed along the suture. In our models, sutural complexity does not predict greater resistance to hydrostatic pressure but it does seem to increase resistance to point loads, such as would be from predators. This result permits discussion of palaeoecological reconstructions on the basis of septal morphology. We further

  7. Comparative cephalopod shell strength and the role of septum morphology on stress distribution.

    Science.gov (United States)

    Lemanis, Robert; Zachow, Stefan; Hoffmann, René

    2016-01-01

    The evolution of complexly folded septa in ammonoids has long been a controversial topic. Explanations of the function of these folded septa can be divided into physiological and mechanical hypotheses with the mechanical functions tending to find widespread support. The complexity of the cephalopod shell has made it difficult to directly test the mechanical properties of these structures without oversimplification of the septal morphology or extraction of a small sub-domain. However, the power of modern finite element analysis now permits direct testing of mechanical hypothesis on complete, empirical models of the shells taken from computed tomographic data. Here we compare, for the first time using empirical models, the capability of the shells of extant Nautilus pompilius, Spirula spirula, and the extinct ammonite Cadoceras sp. to withstand hydrostatic pressure and point loads. Results show hydrostatic pressure imparts highest stress on the final septum with the rest of the shell showing minimal compression. S. spirula shows the lowest stress under hydrostatic pressure while N. pompilius shows the highest stress. Cadoceras sp. shows the development of high stress along the attachment of the septal saddles with the shell wall. Stress due to point loads decreases when the point force is directed along the suture as opposed to the unsupported chamber wall. Cadoceras sp. shows the greatest decrease in stress between the point loads compared to all other models. Greater amplitude of septal flutes corresponds with greater stress due to hydrostatic pressure; however, greater amplitude decreases the stress magnitude of point loads directed along the suture. In our models, sutural complexity does not predict greater resistance to hydrostatic pressure but it does seem to increase resistance to point loads, such as would be from predators. This result permits discussion of palaeoecological reconstructions on the basis of septal morphology. We further suggest that the ratio

  8. Analysis of the anatomy of the maxillary sinus septum using 3-dimensional computed tomography.

    Science.gov (United States)

    Park, Young-Bum; Jeon, Hwan-Su; Shim, June-Sung; Lee, Keun-Woo; Moon, Hong-Seok

    2011-04-01

    Maxillary posterior teeth exhibit a high incidence of periodontal bone and tooth loss. After tooth loss, the edentulous alveolar process of the posterior maxilla is often affected by resorption, which results in loss of vertical bone volume. Moreover, progressive sinus pneumatization leads to a decrease in the alveolar process from the cranial side. The sinus elevation and augmentation surgical technique opened a new way of anchoring endosseous implants despite discernible bone reduction. However, the surgical interventions require in-depth knowledge of maxillary sinus anatomy such as sinus septum and potential variations. The purpose of this study was to investigate the prevalence, location, height, morphology, and orientation of maxillary sinus septa by use of computed tomography (CT) and 3-dimensional imaging. Two hundred patients undergoing implant treatment at the Yonsei University College of Dentistry, Seoul, South Korea, were randomly selected for analysis of maxillary sinus septa. CT and DentaScan (GE Medical Systems, Milwaukee, WI)-reformatted data from 400 sinuses were analyzed with the Preview program (Infinitt, Seoul, South Korea). Three-dimensional images were rendered for measurement by use of the Accurex program (CyberMed, Seoul, South Korea). We found 111 septa in 400 maxillary sinuses (27.7%). This corresponded to 37% of the patients. Among total septa, 25 sinus septa (22.5%) were located in the anterior, 51 (45.9%) in the middle, and 35 (31.5%) in the posterior regions. The directional orientation analyses showed that 106 septa were buccopalatal, 4 were sagittal, and 1 was transverse type. The mean septal heights were 7.78 ± 2.99 and 7.89 ± 3.09 mm in the right and left sinuses, respectively. Three-dimensional CT image analyses may provide useful information that can avoid unnecessary complications during sinus augmentation procedures by facilitating adequate, timely identification of the anatomic structures inherent to the maxillary sinus

  9. Behavior of Shear Link of WF Section with Diagonal Web Stiffener of Eccentrically Braced Frame (EBF of Steel Structure

    Directory of Open Access Journals (Sweden)

    Yurisman

    2010-11-01

    Full Text Available This paper presents results of numerical and experimental study of shear link behavior, utilizing diagonal stiffener on web of steel profile to increase shear link performance in an eccentric braced frame (EBF of a steel structure system. The specimen is to examine the behavior of shear link by using diagonal stiffener on web part under static monotonic and cyclic load. The cyclic loading pattern conducted in the experiment is adjusted according to AISC loading standards 2005. Analysis was carried out using non-linear finite element method using MSC/NASTRAN software. Link was modeled as CQUAD shell element. Along the boundary of the loading area the nodal are constraint to produce only one direction loading. The length of the link in this analysis is 400mm of the steel profile of WF 200.100. Important parameters considered to effect significantly to the performance of shear link have been analyzed, namely flange and web thicknesses, , thickness and length of web stiffener, thickness of diagonal stiffener and geometric of diagonal stiffener. The behavior of shear link with diagonal web stiffener was compared with the behavior of standard link designed based on AISC 2005 criteria. Analysis results show that diagonal web stiffener is capable to increase shear link performance in terms of stiffness, strength and energy dissipation in supporting lateral load. However, differences in displacement ductility’s between shear links with diagonal stiffener and shear links based on AISC standards have not shown to be significant. Analysis results also show thickness of diagonal stiffener and geometric model of stiffener to have a significant influence on the performance of shear links. To perform validation of the numerical study, the research is followed by experimental work conducted in Structural Mechanic Laboratory Center for Industrial Engineering ITB. The Structures and Mechanics Lab rotary PAU-ITB. The experiments were carried out using three test

  10. Investigation of the off-diagonal Seebeck effect and Peltier effect on textured YBa 2Cu 3O 7-δ

    Science.gov (United States)

    He, Z. H.; Zhong, F. Q.; Luo, Y. Y.; Wu, M.; Gavalek, W.; Liang, K. F.; Fung, P. C. W.

    1997-08-01

    Both of the off-diagonal Seebeck effect and the off-diagonal Peltier effect were investigated with the use of the same textured sample YBa 2Cu 3O 7-δ (Y-123) and the same experimental setup. The reliability of the measurement is studied by applying different heat-conductive mediums. The flatness of both of the sample and the heat-conducting block, and the matching between them are found very important for the reduction of the heat resistance. The annealing effect on the Sxz is also studied and found in accordance with that studied by the thermoelectric power.

  11. Preconditioned Diagonally Dominant Properties of H-matrix%H-矩阵的预条件对角占优性

    Institute of Scientific and Technical Information of China (English)

    薛炜

    2014-01-01

    本文主要研究了如何建立适当的预条件矩阵,把一个非对角占优的H-矩阵转化为对角占优矩阵,并得到了相应的结论。并且对此结论给出了相关的数值例子。%This paper mainly studies how to establish appropriate preconditioned matrices for transforming a H-matrix which is non-diagonal y dominant matrix into the diagonal y dominant matrix, obtains the corresponding conclusion and presents the related numerical example of this conclusion.

  12. Non-diagonal charged lepton mass matrix and non-zero {theta}{sub 13}

    Energy Technology Data Exchange (ETDEWEB)

    Acosta, J. Alberto, E-mail: kripton0x@gmail.com [Facultad de Ciencias, CUICBAS, Universidad de Colima, Colima (Mexico); Aranda, Alfredo, E-mail: fefo@ucol.mx [Facultad de Ciencias, CUICBAS, Universidad de Colima, Colima (Mexico); Dual C-P Institute of High Energy Physics (Mexico); Buen-Abad, Manuel A., E-mail: manuelbuenabadnajar@gmail.com [Facultad de Ciencias, CUICBAS, Universidad de Colima, Colima (Mexico); Rojas, Alma D., E-mail: alma.drp@gmail.com [Facultad de Ciencias, CUICBAS, Universidad de Colima, Colima (Mexico)

    2013-01-29

    Assuming that the neutrino mass matrix is diagonalized by the tribimaximal mixing matrix, we explore the textures for the charged lepton mass matrix that render a U{sub PMNS} lepton mixing matrix consistent with data. In particular we are interested in finding the textures with the maximum number of zeros. We explore the cases of real matrices with three and four zeros and find that only ten matrices with three zeros provide solutions in agreement with data. We present the successful Yukawa textures including the relative sizes of their non-zero entries as well as some new and interesting relations among the entries of these textures in terms of the charged lepton masses. We also show that these relations can be obtained directly from a parametrization of the charged lepton mixing matrix U{sub l}.

  13. Explicit Singly Diagonally Implicit Runge-Kutta Methods and Adaptive Stepsize Control for Reservoir Simulation

    DEFF Research Database (Denmark)

    Völcker, Carsten; Jørgensen, John Bagterp; Thomsen, Per Grove

    2010-01-01

    The implicit Euler method, normally refered to as the fully implicit (FIM) method, and the implicit pressure explicit saturation (IMPES) method are the traditional choices for temporal discretization in reservoir simulation. The FIM method offers unconditionally stability in the sense of discrete....... Current reservoir simulators apply timestepping algorithms that are based on safeguarded heuristics, and can neither guarantee convergence in the underlying equation solver, nor provide estimates of the relations between convergence, integration error and stepsizes. We establish predictive stepsize...... control applied to high order methods for temporal discretization in reservoir simulation. The family of Runge-Kutta methods is presented and in particular the explicit singly diagonally implicit Runge-Kutta (ESDIRK) method with an embedded error estimate is described. A predictive stepsize adjustment...

  14. High-precision evaluation of Wigner's d-matrix by exact diagonalization

    CERN Document Server

    Feng, X M; Yang, W; Jin, G R

    2015-01-01

    The precise calculations of the Wigner's d-matrix are important in various research fields. Due to the presence of large numbers, direct calculations of the matrix using the Wigner's formula suffer from loss of precision. We present a simple method to avoid this problem by expanding the d-matrix into a complex Fourier series and calculate the Fourier coefficients by exactly diagonalizing the angular-momentum operator $J_{y}$ in the eigenbasis of $J_{z}$. This method allows us to compute the d-matrix and its various derivatives for spins up to a few thousand. The precision of the d-matrix from our method is about $10^{-14}$ for spins up to $100$.

  15. A Validated Finite Element Procedure for Buckling Simulation of Diagonally Braced Moment Resisting Frames

    Science.gov (United States)

    Lotfollahi, Mehrdad; Mehdi Alinia, Mohammad; Taciroglu, Ertugrul

    2011-09-01

    This paper presents a validated, high fidelity finite element modeling procedure for Diagonally Braced Moment-Resisting Frames (DBMRFs). The model can accurately capture the DBMRF response prior to and through the brace-buckling regime. The model was calibrated through parametric sensitivity studies, which were performed to ascertain the effects of mesh refinement, initial brace imperfection shapes and amplitudes, and the effects of beam-column connection types on the developed analytical model. The validated analytical model can be used for further investigations on the buckling characteristics of the gusset brace system, and for predicting the yield mechanisms, failure modes, and deformation capacities of multistory DBMRFs. The model can also be used for determining frame ductilities, as well as regions of concentration of plastic strains within the frame members and the gusset brace system.

  16. Longitudinal elliptically polarized electromagnetic waves in off-diagonal magnetoelectric split-ring composites.

    Science.gov (United States)

    Chui, S T; Wang, Weihua; Zhou, L; Lin, Z F

    2009-07-22

    We study the propagation of plane electromagnetic waves through different systems consisting of arrays of split rings of different orientations. Many extraordinary EM phenomena were discovered in such systems, contributed by the off-diagonal magnetoelectric susceptibilities. We find a mode such that the electric field becomes elliptically polarized with a component in the longitudinal direction (i.e. parallel to the wavevector). Even though the group velocity [Formula: see text] and the wavevector k are parallel, in the presence of damping, the Poynting vector does not just get 'broadened', but can possess a component perpendicular to the wavevector. The speed of light can be real even when the product ϵμ is negative. Other novel properties are explored.

  17. Fragility and environmental degradation in rural areas of the temperate arid argentinian diagonal

    Directory of Open Access Journals (Sweden)

    Julia Inés Gabella

    2017-01-01

    Full Text Available The aim of this paper is to analyze the climatic characteristics of Patagones district, located in the south of pampeana region (Argentina. We also determine its insertion into the temperate arid argentinian diagonal to understand it as a fragile area of climate transition, exposed to degradation processes derived from human action. Qualitative and quantitative approaches were combined in order to arrive to the objetive. The climatic characterization of the area was conducted by applying the water balance method and the calculation and analysis of the Standardized Precipitation Index (SPI. It was found in Patagones district a permanent disconnection between natural and climatic conditions and the logics of capitalists’ production, which are not adapted to the natural conditions of the territory and have generated environmental degradation of the rural space.

  18. High-gain step-profiled integrated diagonal horn-antennas

    Science.gov (United States)

    Eleftheriades, George V.; Rebeiz, Gabriel M.

    1992-05-01

    A new step-profiled integrated-horn antenna is proposed. The antenna allows gains in the range of 17-20 dB to be achieved using standard (100) silicon wafers. The antenna is diagonally fed and exhibits very good circular symmetry within the 10-dB beamwidth. It has a fundamental Gaussian coupling efficiency of 83 percent. It is demonstrated that the profiled antenna has a radiation pattern similar to that of its smooth envelope horn, provided that the discontinuity between successive wafers does not exceed 0.15 lambda. The integrated stepped-profile horn performs much better than a corresponding smooth 70 deg flare-angle integrated horn of the same aperture size. The integrated step-profile horn is very well-suited for radio-astonomical and remote-sensing millimeter-wave imaging arrays requiring a large number of focal-plane elements.

  19. Non-diagonal boundary conditions for gl(1|1) super spin chains

    Energy Technology Data Exchange (ETDEWEB)

    Grabinski, Andre M; Frahm, Holger, E-mail: frahm@itp.uni-hannover.d [Institut fuer Theoretische Physik, Leibniz Universitaet Hannover, Appelstrasse 2, 30167 Hannover (Germany)

    2010-01-29

    We study a one-dimensional model of free fermions with gl(1|1) supersymmetry and demonstrate how non-diagonal boundary conditions can be incorporated into the framework of the graded quantum inverse scattering method (gQISM) by means of super matrices with entries from a superalgebra. For super Hermitian twists and open boundary conditions subject to a certain constraint, we solve the eigenvalue problem for the super transfermatrix by means of the graded algebraic Bethe ansatz technique (gABA) starting from a fermionic coherent state. For generic boundary conditions the algebraic Bethe ansatz cannot be applied. In this case the spectrum of the super transfermatrix is obtained from a functional relation.

  20. Factorization of second-order strictly hyperbolic operators with non-smooth coefficients and microlocal diagonalization

    Directory of Open Access Journals (Sweden)

    Martina Glogowatz

    2012-08-01

    Full Text Available We study strictly hyperbolic partial differential operators of second-order with non-smooth coefficients. After modeling them as semiclassical Colombeau equations of log-type we provide a factorization procedure on some time-space-frequency domain. As a result the operator is written as a product of two semiclassical first-order constituents of log-type which approximates the modelled operator microlocally at infinite points. We then present a diagonalization method so that microlocally at infinity the governing equation is equal to a coupled system of two semiclassical first-order strictly hyperbolic pseudodifferential equations. Furthermore we compute the coupling effect. We close with some remarks on the results and future directions.