WorldWideScience

Sample records for measuring rig exp-fio-118

  1. Effect of FiO2 in the measurement of VO2 and VCO2 using the E-COXV metabolic monitor.

    Science.gov (United States)

    Ferreruela, M; Raurich, J M; Llompart-Pou, J A; Colomar, A; Ayestarán, I

    2017-11-01

    We evaluated the effect of changes in FiO 2 on the bias and accuracy of the determination of oxygen consumption (V˙O 2 ) and carbon dioxide production (V˙CO 2 ) using the E-COVX monitor in patients with mechanical ventilation. Descriptive of concordance. Intensive Care Unit. Patients with mechanical ventilation. We measured V˙O 2 and V˙CO 2 using the E-COVX monitor. Values recorded were the average in 5min. Two groups of 30 patients. We analyzed: 1) the reproducibility in the measurement of V˙O 2 and V˙CO 2 at FiO 2 0.4, and 2) the effect of the changes in FiO 2 on the measurement of V˙O 2 and V˙CO 2 . Statistical analysis was performed using Bland and Altman test. Bias and accuracy. 1) FiO 2 0.4 reproducibility: The bias in the measurement of V˙O 2 and V˙CO 2 was 1.6 and 2.1mL/min, respectively, and accuracy was 9.7 to -8.3% and 7.2 to -5.2%, respectively, and 2) effect of FiO 2 on V˙O 2 : The bias of V˙O 2 measured at FiO 2 0.4 and 0.6 was -4.0mL/min and FiO 2 0.4 and 0.8 was 5.2mL/min. Accuracy between FiO 2 0.4 and 0.6 was 11.9 to -14.1%, and between FiO 2 0.4 and 0.8 was 43.9 to -39.7%. The E-COVX monitor evaluates V˙O 2 and V˙CO 2 in critical patients with mechanical ventilation with a clinically acceptable accuracy until FiO 2 0.6. Copyright © 2017 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  2. Heat-Transfer and Pressure Measurements from a Flight Test of the Third 1/18-Scale Model of the Titan Intercontinental Ballistic Missile up to a Mach Number of 3.86 and Reynolds Number per Foot of 23.5 x 10(exp 6) and a Comparison with Heat Transfer

    Science.gov (United States)

    Graham, John B., Jr.

    1958-01-01

    Heat-transfer and pressure measurements were obtained from a flight test of a 1/18-scale model of the Titan intercontinental ballistic missile up to a Mach number of 3.86 and Reynolds number per foot of 23.5 x 10(exp 6) and are compared with the data of two previously tested 1/18-scale models. Boundary-layer transition was observed on the nose of the model. Van Driest's theory predicted heat-transfer coefficients reasonably well for the fully laminar flow but predictions made by Van Driest's theory for turbulent flow were considerably higher than the measurements when the skin was being heated. Comparison with the flight test of two similar models shows fair repeatability of the measurements for fully laminar or turbulent flow.

  3. Electronic temperature control and measurements reactor fuel rig circuits

    Energy Technology Data Exchange (ETDEWEB)

    Glowacki, S W

    1980-01-01

    The electronic circuits of two digital temperature meters developed for the thermocouple of Ni-NiCr type are described. The output thermocouple signal as converted by means of voltage-to-freguency converter. The frequency is measured by a digital scaler controled by quartz generator signals. One of the described meter is coupled with digital temperature controler which drives the power stage of the reactor rig heater. The internal rig temperature is measured by the thermocouple providing the input signal to the mentioned voltage-to-frequency converter, that means the circuits work in the negative feedback loop. The converter frequency-to-voltage ratio is automatically adjusted to match to thermocouple sensitivity changes in the course of the temperature variations. The accuracy of measuring system is of order of +- 1degC for thermocouple temperature changes from 523 K up to 973 K (50degC up to 700degC).

  4. Flow Rate Measurement in Multiphase Flow Rig: Radiotracer and Conventional

    International Nuclear Information System (INIS)

    Nazrul Hizam Yusoff; Noraishah Othman; Nurliyana Abdullah; Amirul Syafiq Mohd Yunos; Rasif Mohd Zain; Roslan Yahya

    2015-01-01

    Applications of radiotracer technology are prevalent throughout oil refineries worldwide, and this industry is one of the main users and beneficiaries of the technology. Radioactive tracers have been used to a great extent in many applications i.e. flow rate measurement, RTD, plant integrity evaluation and enhancing oil production in oil fields. Chemical and petrochemical plants are generally continuously operating and technically complex where the radiotracer techniques are very competitive and largely applied for troubleshooting inspection and process analysis. Flow rate measurement is a typical application of radiotracers. For flow measurements, tracer data are important, rather than the RTD models. Research is going on in refining the existing methods for single phase flow measurement, and in developing new methods for multiphase flow without sampling. The tracer techniques for single phase flow measurements are recognized as ISO standards. This paper presents technical aspect of laboratory experiments, which have been carried out using Molybdenum-99 - Mo99 (radiotracer) to study and determine the flow rate of liquid in multiphase flow rig. The multiphase flow rig consists of 58.7 m long and 20 cm diameter pipeline that can accommodate about 0.296 m 3 of liquid. Tap water was used as liquid flow in pipeline and conventional flow meters were also installed at the flow rig. The flow rate results; radiotracer and conventional flow meter were compared. The total count method was applied for radiotracer technique and showed the comparable results with conventional flow meter. (author)

  5. The electronic temperature control and measurements reactor fuel rig circuits

    International Nuclear Information System (INIS)

    Glowacki, S.W.

    1980-01-01

    The electronic circuits of two digital temperature meters developed for the thermocouple of Ni-NiCr type are described. The output thermocouple signal as converted by means of voltage-to-freguency converter. The frequency is measured by a digital scaler controled by quartz generator signals. One of the described meter is coupled with digital temperature controler which drives the power stage of the reactor rig heater. The internal rig temperature is measured by the thermocouple providing the input signal to the mentioned voltage-to-frequency converter, that means the circuits work in the negative feedback loop. The converter frequency-to-voltage ratio is automatically adjusted to match to thermocouple sensitivity changes in the course of the temperature variations. The accuracy of measuring system is of order of +- 1degC for thermocouple temperature changes from 523 K up to 973 K (50degC up to 700degC). (author)

  6. What Really Rigs Up RIG-I?

    Science.gov (United States)

    Barik, Sailen

    2016-01-01

    RIG-I (retinoic acid-inducible gene 1) is an archetypal member of the cytoplasmic DEAD-box dsRNA helicase family (RIG-I-like receptors or RLRs), the members of which play essential roles in the innate immune response of the metazoan cell. RIG-I functions as a pattern recognition receptor that detects nonself RNA as a pathogen-associated molecular pattern (PAMP). However, the exact molecular nature of the viral RNAs that act as a RIG-I ligand has remained a mystery and a matter of debate. In this article, we offer a critical review of the actual viral RNAs that act as PAMPs to activate RIG-I, as seen from the perspective of a virologist, including a recent report that the viral Leader-read-through transcript is a novel and effective RIG-I ligand. © 2016 S. Karger AG, Basel.

  7. Anastomose arterial com fio de polidioxanona e fio de polipropileno. Estudo comparativo em cães Arterial anastomose with polydioxanone and polypropilene suture. Comparative study in dogs

    OpenAIRE

    Eloísa de Brida Tormena; Carlos Edmundo Rodrigues Fontes; César Orlando Peralta Bandeira; Amaury José Teixeira Nigro; Marcos Victor Ferreira; Lia Yoneka Toda; Fabiana de Cássia Merenda

    2002-01-01

    Este estudo teve por objetivo comparar os efeitos do fio absorvível de polidioxanona com o fio inabsorvível de polipropileno, em anastomoses término-terminais, em artérias femorais de cães. Foram utilizados 20 cães, separados em dois grupos, para observação no 7º e no 30º dia de pós-operatório. Cada cão teve suas artérias femorais seccionadas e aproximadas em um lado com pontos separados de fio de polidioxanona 6-0, e no lado contralateral com o fio de polipropileno 6-0. A escolha do fio foi ...

  8. Rig it right! Maya animation rigging concepts

    CERN Document Server

    O'Hailey, Tina

    2013-01-01

    Rigging a character can be a complicated undertaking. Move from a bi-pedal character to a quad- or poly-pedal and, well, things just got real. Where do you begin? Unlike all of those button-pushing manuals out there, Rig it Right! breaks down rigging so that you can achieve a fundamental understanding of the concept, allowing you to rig more intuitively in your own work. Veteran animation professor Tina O'Hailey will get you up and rigging in a matter of hours with step-by-step tutorials covering multiple animation control types, connection methods, interactive skinning, Blend

  9. Advancing rig design: latest rig technologies improving efficiency and safety

    Energy Technology Data Exchange (ETDEWEB)

    Greenaway, R.

    1997-12-01

    Recent advances in drilling rig technologies that improve the ways for finding oil and natural gas, and are also solving some safety and transportation problems, have been reviewed. The coiled tubing drilling rig developed by joint venture TransOcean Ensign Drilling Technology was one of the innovations described. It is able to run a three-and-a-quarter inch coiled tubing, the only system capable of doing this in a land-based application. Tesco Corporation`s new casing drilling rig, which is expected to lower the cost of moving the rig, and Brinkerhoff Drilling`s new generation modular (NGM)-rig, claimed to be the most mobile rig in North America, are other new developments worthy of note. Tesco`s casing drilling rig has the potential to reduce drilling costs by as much as 30 to 40 per cent, while the NGM-rig could reduce rig mobilization time by 50 to 80 per cent, and the number of wells drilled by the same rig could increase by 20 per cent, due to the NGM-rig`s versatility and flexibility.

  10. Anastomose arterial com fio de polidioxanona e fio de polipropileno. Estudo comparativo em cães Arterial anastomose with polydioxanone and polypropilene suture. Comparative study in dogs

    Directory of Open Access Journals (Sweden)

    Eloísa de Brida Tormena

    2002-03-01

    Full Text Available Este estudo teve por objetivo comparar os efeitos do fio absorvível de polidioxanona com o fio inabsorvível de polipropileno, em anastomoses término-terminais, em artérias femorais de cães. Foram utilizados 20 cães, separados em dois grupos, para observação no 7º e no 30º dia de pós-operatório. Cada cão teve suas artérias femorais seccionadas e aproximadas em um lado com pontos separados de fio de polidioxanona 6-0, e no lado contralateral com o fio de polipropileno 6-0. A escolha do fio foi feita por sorteio, totalizando 40 anastomoses. Para análise estatística dos resultados aplicaram-se os testes de Fisher, Mac Nemar, Wilcoxon, Mann-Witney e o teste T de Student (a ≤ 0,05. Nas avaliações clínicas não foram observadas diferenças significantes entre os fios utilizados. Os resultados obtidos nas avaliações arteriográfica e macroscópica dos segmentos arteriais foram semelhantes, assim como na análise histológica morfológica. Na análise histológica morfométrica o fio de polipropileno apresentou número de células gigantes de corpo estranho significativamente maior que o fio de polidioxanona aos 7 e 30 dias de pós-operatório. Os resultados nos permitem concluir que, apesar da maior reação de corpo estranho observada com o fio de polipropileno, o fio de polidioxanona apresentou resultados semelhantes ao fio de polipropileno, em anastomoses arteriais em cães.The objetive of this study was to compare the effects of the absorbable polidioxanone suture to the nonabsorbable polypropylene suture, in end-to-end anastomoses, using dog’s femoral arteries. Twenty dogs were separated in two groups for observation on the 7th and 30th post-operatory day. Each dog had its femoral arteries seccioned and then aproximated one side with separate stitches of polidioxanone 6-0 suture, and the other side with polypropylene 6-0 suture. For the statistical studies Fisher, Mac nemar, Wilsoxon, Mann-Witney and T of Student tests (a

  11. Electron Excitation Cross Sections for the S II Transitions: 3s(exp 2)3p(exp 3) 4S(exp o) approaches 3s(exp 2)3p(exp 3) 2D(exp o), 2P(exp o), and 3s3p(exp 4) 4P

    Science.gov (United States)

    Liao, C.; Chutjian, A.; Hitz, D.; Tayal, S. S.

    1997-01-01

    Experimental and theoretical collisional excitation cross sections are reported for the transitions 3s(exp 2)3p(exp 3)4S(exp o) approaches 3s(exp 2)3p(exp 3) 2D(exp o), 2P(exp o), and 3s3P(exp 4) 4P in S II. The transition wavelengths (energies) are 6716 A (1.85 eV), 4069 A (3.05 eV), and 1256 A (9.87 eV), respectively. In the experiments, use is made of the energy-loss merged-beams method. The metastable fraction of the S II beam was assessed and minimized. The contribution of elastically scattered electrons was reduced by the use of a lowered solenoidal magnetic field and a modulated radio-frequency voltage on the analyzing plates and by retarding grids to reject the elastically scattered electrons with larger Larmor radii. For each transition, comparisons are made among experiments, the new 19 state R-matrix calculation, and three other close-coupling calculations.

  12. Hoisting and Rigging (Formerly Hoisting and Rigging Manual)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    This standard is intended as a reference document to be used by supervisors, line managers, safety personnel, equipment operators, and any other personnel responsible for safety of hoisting and rigging operations at DOE sites. It quotes or paraphrases the US OSHA and ANSI requirements. It also encompasses, under one cover,hoisting and rigging requirements, codes, standards, and regulations, eliminating the need to maintain extensive (and often incomplete) libraries of hoisting and rigging standards throughout DOE. The standard occasionally goes beyond the minimum general industry standards established by OSHA and ANSI, and also delineates the more stringent requirements necessary to accomplish the complex, diversified, critical, and often hazardous hoisting and rigging work found with the DOE complex.

  13. Accuracy of an indirect calorimeter for mechanically ventilated infants and children: the influence of low rates of gas exchange and varying FIO2.

    Science.gov (United States)

    Joosten, K F; Jacobs, F I; van Klaarwater, E; Baartmans, M G; Hop, W C; Meriläinen, P T; Hazelzet, J A

    2000-08-01

    To test the accuracy and validity of the Deltatrac II MBM-200 metabolic monitor for use in mechanically ventilated infants and children in the pediatric intensive care unit. Laboratory validation of an indirect calorimeter with a ventilated lung model. The influence of low tidal volumes and low levels of oxygen consumption (V(O2)) and carbon dioxide production (V(CO2)) in combination with different levels of inspired oxygen concentrations (F(IO2)) was investigated. University research laboratory. Low tidal volumes were provided with two intermittent flow types of ventilators, a Servo 300 and a Servo 900C. A butane flame with a V(O2) approximating 20 mL/min and 40 mL/min was ventilated. To investigate the effect of different levels of F(IO2) on the accuracy of V(O2), V(CO2), and respiratory quotient (RQ), measurements were performed at F(IO2) target values of 0.25, 0.40, and 0.60. No significant differences were found between the ventilators regarding V(O2), V(CO2), and RQ measurements. The mean deviation of V(O2) increased significantly with increasing F(IO2) to -7.98% with a V(O2) of 21.0 mL/min and to -8.46% with a V(O2) of 38.9 mL/min (F(IO2), 0.558) with a variability (2 SD) of +/- 4.86% and +/- 6.82%, respectively. The mean deviation and variability of V(CO2) in all tests remained within 8%. The mean deviation of RQ increased significantly with increasing F(IO2) to 5.5% with a V(O2) of 21.0 mL/min and to 5.69% with a V(O2) of 38.9 mL/min (F(IO2), 0.558) with a variability (2 SD) of +/- 5.62% and +/- 5.76%, respectively. The minute to minute delivered F(IO2) fluctuated significantly when increasing the level of F(IO2). The Deltatrac II MBM-200 metabolic monitor appears accurate for low levels of V(O2) and V(CO2) during mechanical ventilation with F(IO2) levels up to 0.390. With increasing F(IO2) to 0.558, the increase in deviation of V(O2) for single measurements can be of clinical relevance for mechanically ventilated infants and children. The increased

  14. Joint test rig for tests and calibration of different methods of two-phase mass flow measurement

    International Nuclear Information System (INIS)

    John, H.; Erbacher, F.; Wanner, E.

    1975-01-01

    On behalf of the Federal Ministry of Research and Technology, the Institute of Reactor Components (IRB) has begun building a test rig which will be used for testing and calibrating the methods of measuring non-steady state two-phase mass flows developed by various research agencies. The test rig is designed for the generation of steam-water mixtures of any mixing ratio and a maximum pressure of 160 data. Depending on the mixing ratio, the mass flow will reach a maximum level of 10 to 20 t/h. The conceptual design phase of the test rig has largely been finished, the component ordering phase has begun. (orig.) [de

  15. Measurement techniques for AGR circulators in a full-density rig

    International Nuclear Information System (INIS)

    Watson, I.; Wilson, R.R.

    1977-01-01

    Safety and reliability are the most important factors of a nuclear power plant. This applies in particular to the circulators used to drive the high-density CO 2 around the reactor core and boiler circuits. Under operating conditions, very high sound-pressure levels are generated which could excite components and cause possible fatigue failures. Failures of this type were experienced on the original axial blowers for the Hinkley 'A' Magnox reactor and, following this, a stringent test plan was specified for the AGR circulators. The present paper describes some of the techniques used to measure strain, sound and vibration on circulators in a full-density rig. This rig reproduces the actual reactor working conditions of 300 0 C and 4.1 MN m -2 with gas velocities up to 120 m s -1 . Under these conditions sound-pressure levels of up to 172 dB are generated. This programme of circulator testing has continued for the past 10 years. During this period many obstacles and difficulties were encountered. Some of these problems, together with the solutions found, are discussed. (author)

  16. Understanding Rig Rates

    OpenAIRE

    Petter Osmundsen; Knut Einar Rosendahl; Terje Skjerpen

    2013-01-01

    We examine the largest cost component in offshore development projects, drilling rates, which have been high over the last years. To our knowledge, rig rates have not been analysed empirically before in the economic literature. By econometric analysis we examine the effects on Gulf of Mexico rig rates of gas and oil prices, rig capacity utilization, contract length and lead time, and rig specific characteristics. Having access to a unique data set containing contract information, we are able ...

  17. The Winfrith 9MW heat transfer rig

    International Nuclear Information System (INIS)

    Obertelli, J.D.

    1976-01-01

    The Winfrith 9MW Rig is used for studying heat transfer and flow resistance in a variety of test sections at system pressures up to 68 bar. The basic rig and its instrumentation are discussed together with the characteristics of the test section design. The rig has been used in studies involving the full scale simulation of Steam Generating Heavy Water (SGHW) fuel assemblies and the paper discusses the measurements made in this type of study. (author)

  18. Endurance test on IR rig for RI production

    International Nuclear Information System (INIS)

    Chung, Heung June; Youn, Y. J.; Han, H. S.; Hong, S. B.; Cho, Y. G.; Ryu, J. S.

    2000-12-01

    This report presents the pressure drop, vibration and endurance test results for IR rig for RI production which were desigened and fabricated by KAERI. From the pressure drop test results, it is noted that the flow rate through the IR rig corresponding to the pressure drop of 200 kPa is measured to be about 3.12 kg/sec. Vibration frequency for the IR rig ranges from 13 to 17 Hz. RMS(Root Mean Square) displacement for the IR rig is less than 30 μm, and the maximum displacement is less than 110μm. These experimental results show that the design criteria of IR rig meet the HANARO limit conditions. Endurance test results show that the appreciable fretting wear for the IR rig does not occur, however tiny trace of wear between contact points is observed

  19. The art of rigging

    CERN Document Server

    Biddlecombe, George

    1990-01-01

    The best manual ever produced on rigging a sailing ship, based on extensively revised and updated 1848 edition prepared by Biddlecombe, Master in the Royal Navy. Complete definition of terms, on-shore operations, process of rigging ships, reeving the running rigging and bending sails, rigging brigs, yachts and small vessels, more. 17 plates.

  20. Utilidad de la relación Sao2/Fio2 en la evaluación del grado de compromiso pulmonar en pacientes críticos

    Directory of Open Access Journals (Sweden)

    Alonso Gómez Duque

    2002-01-01

    Full Text Available Background: Arteriovenous admixture or intrapulmonary shunt and the relation between PaO2 and FI02 (PaO2/FiO2 have been advocated as the main indicators of pulmonary function. Because the Pa02 is a measure of the oxygen given to the tissues, as well as the Sa02, we could expect a close relationship between the Pa02IFI02 index and a new one, the SaO2/FiO2 index, Methods: We conducted a prospective study in a cohortofl07 patients with different pathologies in an Intensive Care Unit, collecting 507 samples of arterial and central venous gases and measuring the Sa02 by pulse oximeter at the same time. PaO2/FiO2 and Sa O2/FiO2, as well as intrapulmonary shunt using invasive and noninvasive methods, were caIculated. The Lung Injury Score (LIS and the Multiple Organ Dysfunction score were calculated too. Results: We found a good correlation between Sa O2/FiO2 and PaO2/FiO2. (R2=0,81,R=0.9, and between the intrapulmonary shuntfraction calculated with invasive and noninvasive methods.(R2=0.75, R=0.86. The data were correlationed with a simple linear regression analysis. Five groups of SaO2/FiO2 were found and a punctuation from Oto 4 was established for them, in a similar approach to the one used by Murray in the Lung Injury Score (LIS and Marshall in the Multiple Organ Dysfunction score. By using this punctuation, we replaced the PaO2/FiO2 by the SaO2/FiO2 in the scale and recalculated the LIS finding a good correlation between the score with PaO2/FiO2 and the one with SaO2/FiO2 (R2=0.94,R=0.96. The same was true for the correlation between the Marshall score with PaO2/FiO2 and the one with SaO2/FiO2. (R2=O.85, R=0.92. The correlation was mantained when a stratified analysis was made according to the degree of severity of the pulmonary injury. Conclusions: SaO2/FiO2 is an useful indicator of the oxygenation in a similar way as the PaO2/FiO2 índex, It could be incorporated into the LIS and Marshall score with similar results. The usefulness of the

  1. Controle dos vasos renais usando clips vasculares e fio cirúrgico em nefrectomias vídeo-assistidas de doadores vivos

    Directory of Open Access Journals (Sweden)

    Alcides José Branco Filho

    Full Text Available OBJETIVO: A nefrectomia laparoscópica em doadores vivos para transplante renal vem assumindo um papel importante na era das cirurgias minimamente invasivas, acarretando menor morbidade aos doadores, e resultados semelhantes à técnica aberta no que se refere ao enxerto renal. O objetivo do presente artigo é relatar a experiência do nosso serviço utilizando a técnica de controle dos vasos renais usando fio cirúrgico e clips vasculares. MÉTODO: Foram realizadas 45 nefrectomias utilizando a técnica vídeo-assistida, com ligadura dos vasos renais com clips de titânio (LT-300 e fio cirúrgico. As variáveis analisadas foram tempo cirúrgico, perda sangüínea, tempo de isquemia quente, permanência hospitalar, necessidade de conversão e complicações. RESULTADOS: O procedimento foi realizado com sucesso em todos os casos. O tempo cirúrgico médio foi de 118 minutos, com perda sangüínea estimada em 84ml e tempo de isquemia quente de 4,3 minutos. Dois casos de íleo prolongado, uma lesão de veia gonadal, um escape de artéria renal e uma necrose de ureter foram observados. A permanência hospitalar média foi de 3,7 dias. O uso de clips vasculares e fio cirúrgico reduziu a perda de tecido venoso comparado à técnica com staplers e gerou redução de custos. CONCLUSÕES: A nefrectomia vídeo-assistida com a técnica descrita é factível e mostrou ser efetiva na contenção de gastos e na redução de tecido venoso perdido.

  2. Study in flow rig by using radiotracer

    International Nuclear Information System (INIS)

    Widatalla, R. K.

    2012-06-01

    Application of radioisotope technology have proved itself to be effective techniques for troubleshooting and optimizing industrial process in petrochemical industry In this study gamma scanning technique has been employed for better understanding of malfunctions by using the flow rig system. The scanning were carried out using 9 9mT C gamma radiation source with activity of 1 mCi and quantity of 5 ml to measure the flow rate for the water flow rig The experiment was repeated by reducing the data interval time to get more precise result. The investigations were also carried out using 5 ml of 9 9mT C with activity of 0.3 mCi for measuring the Residence Time Distribution (RTD) inside the flow rig tank which enables calculating the effective volume for the operating tank and its dead volume. The results proved that the technique is sensitive, reliable and can be adopted to investigate industrial reactors. (Author)

  3. One big rig, two valuable functions

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2004-11-01

    A hybrid coil tubing and conventional workover rig, tailor-made for conditions on Alaska's remote North Slope is described. The dual function rig, owned by BP Exploration, towers 142 feet above the barren Arctic tundra, and weighs between 1.5 and 2 million pounds, rests on eight enormous wheels that stand 11.5 feet tall and 3.5 feet wide, and is supported by 64 smaller tires in between. The rig includes the hybrid coiled tubing rig and a conventional workover rig; it exerts less than 100 pounds per square inch of pressure on the tender Arctic surface as it moves forward at a top speed of two miles per hour. It is considered by its developers as the next-step change in providing cost-effective access to reserves in the large, mature and remote oilfields such as those of Alaska's Prudhoe Bay. The rig is the product of cooperation between Schlumberger expertise in coiled tubing drilling and Nordic-Calista's know-how of jointed pipe operations and operating rigs in an Arctic environment. It is the first time in Prudhoe Bay, and probably in the world, that a coiled tubing unit was installed on a rig to do coiled-tubing sidetracks, i.e to drill a secondary wellbore away from the original wellbore. Since the first unit was commissioned in 1996, the rig has drilled 280 wells. Rig No. 2, much improved and commissioned in 2002, drilled about 30 wells to date. Unlike Rig No, 1, Rig No. 2 can change reels without a crane, and it has a hydraulic pipe skate that moves jointed pipe to and from the rig floor without human aid. The expectation is that using this rig it will be possible to do micro-hole exploration drilling on the North Slope (i.e. drilling a small surface hole with jointed pipe and then switch to coiled tubing), substantially cutting the cost of exploration.

  4. Wi-Fi Salvador: mapeamento colaborativo e redes sem fio no Brasil

    OpenAIRE

    Lemos, André; Pastor, Leonardo; Oliveira, Nelson

    2012-01-01

    O trabalho faz uma breve demonstração de políticas públicas para inclusão digital por meio da disponibilização do acesso à internet por meio de redes sem fio e discute a forma como as pessoas se relacionam com os lugares, de acordo com a existência ou inexistência de acessibilidade à internet. O objetivo é discutir o acesso à internet pelas redes sem fio no Brasil e, mais especificamente, na cidade de Salvador. Este trabalho é fruto de pesquisa realizada no âmbito do Grupo de Pesquisa em Cibe...

  5. Equipment available for automating rig operations

    International Nuclear Information System (INIS)

    McNair, W.L.

    1990-01-01

    Several manufacturers are producing automated rig equipment, from complete systems to individual functions for existing drilling rigs. Significant improvements in well site time, costs of operations, and improved drilling performance have led drilling contractors to install this equipment on their rigs. This paper details some of the equipment available for automating rigs

  6. Field Demonstraton of Existing Microhole Coiled Tubing Rig (MCTR) Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kent Perry; Samih Batarseh; Sheriff Gowelly; Thomas Hayes

    2006-05-09

    The performance of an advanced Microhole Coiled Tubing Rig (MCTR) has been measured in the field during the drilling of 25 test wells in the Niobrara formation of Western Kansas and Eastern Colorado. The coiled tubing (CT) rig designed, built and operated by Advanced Drilling Technologies (ADT), was documented in its performance by GTI staff in the course of drilling wells ranging in depth from 500 to nearly 3,000 feet. Access to well sites in the Niobrara for documenting CT rig performance was provided by Rosewood Resources of Arlington, VA. The ADT CT rig was selected for field performance evaluation because it is one of the most advanced commercial CT rig designs that demonstrate a high degree of process integration and ease of set-up and operation. Employing an information collection protocol, data was collected from the ADT CT rig during 25 drilling events that encompassed a wide range of depths and drilling conditions in the Niobrara. Information collected included time-function data, selected parametric information indicating CT rig operational conditions, staffing levels, and field observations of the CT rig in each phase of operation, from rig up to rig down. The data obtained in this field evaluation indicates that the ADT CT rig exhibited excellent performance in the drilling and completion of more than 25 wells in the Niobrara under varied drilling depths and formation conditions. In the majority of the 25 project well drilling events, ROP values ranged between 300 and 620 feet per hour. For all but the lowest 2 wells, ROP values averaged approximately 400 feet per hour, representing an excellent drilling capability. Most wells of depths between 500 and 2,000 feet were drilled at a total functional rig time of less than 16 hours; for wells as deep at 2,500 to 3,000 feet, the total rig time for the CT unit is usually well under one day. About 40-55 percent of the functional rig time is divided evenly between drilling and casing/cementing. The balance of

  7. Graded algebras of the second rank and integration of nonlinear equations Ysub(z)sub(z) = exp(2Y) - exp(-2Y), Ysub(z)sub(z) = 2 exp(Y) - exp(-2Y)

    International Nuclear Information System (INIS)

    Leznov, A.N.; Smirnov, V.G.

    1981-01-01

    In the terms of the notions of the theory of infinite-dimensional algebras of finite growth of the second rank, we have derived solutions to the equations Ysub(z)sub(z) = exp(2Y) - exp(-2Y); Ysub(z)sub(z) = 2 exp(Y) - exp(-2Y) dependent on two arbitrary functions. (orig.)

  8. Design and Checkout of a High Speed Research Nozzle Evaluation Rig

    Science.gov (United States)

    Castner, Raymond S.; Wolter, John D.

    1997-01-01

    The High Flow Jet Exit Rig (HFJER) was designed to provide simulated mixed flow turbojet engine exhaust for one- seventh scale models of advanced High Speed Research test nozzles. The new rig was designed to be used at NASA Lewis Research Center in the Nozzle Acoustic Test Rig and the 8x6 Supersonic Wind Tunnel. Capabilities were also designed to collect nozzle thrust measurement, aerodynamic measurements, and acoustic measurements when installed at the Nozzle Acoustic Test Rig. Simulated engine exhaust can be supplied from a high pressure air source at 33 pounds of air per second at 530 degrees Rankine and nozzle pressure ratios of 4.0. In addition, a combustion unit was designed from a J-58 aircraft engine burner to provide 20 pounds of air per second at 2000 degrees Rankine, also at nozzle pressure ratios of 4.0. These airflow capacities were designed to test High Speed Research nozzles with exhaust areas from eighteen square inches to twenty-two square inches. Nozzle inlet flow measurement is available through pressure and temperature sensors installed in the rig. Research instrumentation on High Speed Research nozzles is available with a maximum of 200 individual pressure and 100 individual temperature measurements. Checkout testing was performed in May 1997 with a 22 square inch ASME long radius flow nozzle. Checkout test results will be summarized and compared to the stated design goals.

  9. An Optical Fiber Bundle Sensor for Tip Clearance and Tip Timing Measurements in a Turbine Rig

    Directory of Open Access Journals (Sweden)

    María Asunción Illarramendi

    2013-06-01

    Full Text Available When it comes to measuring blade-tip clearance or blade-tip timing in turbines, reflective intensity-modulated optical fiber sensors overcome several traditional limitations of capacitive, inductive or discharging probe sensors. This paper presents the signals and results corresponding to the third stage of a multistage turbine rig, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on the turbine casing. To eliminate the influence of light source intensity variations and blade surface reflectivity, the sensing principle is based on the quotient of the voltages obtained from the two receiving bundle legs. A discrepancy lower than 3% with respect to a commercial sensor was observed in tip clearance measurements. Regarding tip timing measurements, the travel wave spectrum was obtained, which provides the average vibration amplitude for all blades at a particular nodal diameter. With this approach, both blade-tip timing and tip clearance measurements can be carried out simultaneously. The results obtained on the test turbine rig demonstrate the suitability and reliability of the type of sensor used, and suggest the possibility of performing these measurements in real turbines under real working conditions.

  10. {open_quote}Nintendo Rig{close_quote} lets two men do work of three on traditional servicing rig

    Energy Technology Data Exchange (ETDEWEB)

    Rintoul, B.

    1996-01-01

    New well servicing rig saves costs and increases safety by using a robot derrickman. The rigs is called the Nintendo Rig, taking the name from the joystick that controls the robot on the racking board 25 feet above the ground. An automated tong/slip package permanently mounted on the front of the rig handles pipe and rods on the ground.

  11. The mobile rig industry

    International Nuclear Information System (INIS)

    Karlsen, J.K.

    1992-08-01

    This study is part of the project ''A competitive Norway'', based on the theories and methods presented in the book ''The competitive advantage of nations'', by Michael E. Porter. The rig market may be segmented according to the type of service, the geographical market and the type of equipment. The focus of the report is exploration and appraisal drilling using jackup rigs and semi-submersible rigs in the Northwestern European market. Market shares of Norwegian, other European and US suppliers in the jackup and semi-submerisible market segments on the Norwegian continental shelf and the entire Northwestern market are presented. The main driving force behind the rig demand is the price of oil, but technological trends and changes in relative importance of the various geographical markets are also important. The industry is fairly fragmented on the supplier side, while the oil companies as customers have substantial bargaining power. There are high exit barriers because of the high capital intensity of the business. Combined with a highly volatile demand, this forces the industry through cycles of low capacity utilization and depressed rig day rates. 8 refs., 19 figs., 2 tabs

  12. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2 and 118-H-3 Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    K. L. Vialetti

    2008-05-20

    This report presents the final hazard categorization for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  13. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    International Nuclear Information System (INIS)

    Rodovsky, T.J.

    2006-01-01

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site

  14. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    T. J. Rodovsky

    2006-12-06

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  15. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    T. J. Rodovsky

    2007-04-12

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  16. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    International Nuclear Information System (INIS)

    TRodovsky, T.J.

    2007-01-01

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site

  17. 40th annual Reed rig census

    International Nuclear Information System (INIS)

    Fitts, R.L.; Stokes, T.A.

    1992-01-01

    This paper reports that declines characterize the 1992 rig census-in the number of available drilling rigs, in the number of active rigs, in rig utilization rate, in the number of rig owners and in industry optimism. The number of rotary rigs available for U.S. drilling fell by 255 units (11.3%) during the past 12 months, an attrition rate almost four times greater than in 1991. But despite the high attrition, only 59.7% of remaining rigs were working during the time the census was taken. Results of the 1992 census bring emphasis to an industry trend that became apparent in early 1991. The major oil companies, and many independents, continued their exodus form the U.S., and the remaining independents, which were hurt by low natural gas prices and unfavorable tax treatment of intangible drilling costs, were not able to pick u the drilling slack. Consequently, the past year has been disastrous for many U.S. drilling contractors, and the outlook for this industry segment remains bleak

  18. Rig`s electricity to power top drive drilling system

    Energy Technology Data Exchange (ETDEWEB)

    Liderth, D.

    1996-05-01

    Permanent magnet brushless electric motors to supply torque to more space-efficient top drive drilling assemblies was the solution designed by Kaman Electromagnetic Corporation, working hand-in-hand with Calgary-based Tesco Drilling Technology, to remedy problems created by the bulkiness of standard hydraulic top drive systems. The biggest advantage of using electric over hydraulic top drive systems is the ability to tap into the rig`s existing power source, which lowers both cost and effort. A better power to weight ratio and reduced maintenance requirements are other desirable advantages.

  19. 39th annual Reed rig census

    International Nuclear Information System (INIS)

    Crowhurst, M.E.; Fitts, R.L.

    1991-01-01

    This paper reports on cutbacks in U.S. exploration and development drilling during the first half of 1991 which squeezed most of the optimism out of the drilling industry. Just how rough the year has been is underscored by the results of this year's rig census. The number of rotary rigs available for U.S. drilling declined by only 69 units (3%) during the past 12 months. But despite those withdrawals from competition, only 66% of the remaining rigs were working at the time the census was taken. Results of the 1991 census contrasted sharply with the stability and optimism that seemed apparent a year ago when 72% of the available rig fleet met the census definition of active. At that time, the mini-boom in horizontal drilling coupled with tax-credit- driven gas drilling led to a relatively high rig utilization rate and suggested that rig supply and demand might be close to an economically acceptable balance. However, it quickly became apparent in early 1991 that industry optimism was unjustified. Horizontal drilling began to drop and the lowest natural gas prices in 12 years triggered rapid declines in gas drilling. Although oil prices have been relatively stable and above $18 per bbl since January 1989, most major operators have concluded that a better return on investment can be had outside the U.S. and have drastically cut their domestic drilling budgets. These factors, combined with softened energy demand from the worldwide recession, further slowed U.S. drilling. The long awaited balance between rig supply and demand has seemingly slipped away. The 1991 Reed rig census describes an industry facing several more rough years. Details of this year's census include: The available U.S. fleet now stands at 2,251 rigs, down by 69 from the 2,320-unit total in 1990, and the lowest since 1976. Rigs meeting the census definition of active numbered 1,485, down 192 (11.4%) from the 1,677 active rigs counted a year earlier

  20. Drilling rig mast

    Energy Technology Data Exchange (ETDEWEB)

    Bulgakov, E.S.; Barashkov, V.A.; Lebedev, A.I.; Panin, N.M.; Sirotkin, N.V.

    1981-01-07

    A drilling rig mast is proposed that contains a portal with a carrier shaft hinged to it and struts with stays. In order to decrease the time expended in the assembly and dessembly of the drilling rig, the portal is constructed from mobile and immobile parts that are connected together by a ball pivot; the immobile section of the portal has a T-shaped recess for directing the mobile section.

  1. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    J.D. Ludowise

    2009-06-17

    This report presents the final hazard categorization for the remediation of the 118-D-1, 118-D-2, 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site. A material at risk calculation was performed that determined the radiological inventory for each burial ground to be Hazard Category 3.

  2. Replacement team of mining drilling rigs

    OpenAIRE

    Hamodi, Hussan; Lundberg, Jan

    2014-01-01

    This paper presents a practical model to calculate the optimal replacement time (ORT) of drilling rigs used in underground mining. As a case study, cost data for drilling rig were collected over four years from a Swedish mine. The cost data include acquisition, operating, maintenance and downtime costs when using a redundant rig. A discount rate is used to determine the value of these costs over time. The study develops an optimisation model to identify the ORT of a mining drilling rig which ...

  3. A Comparison Between Measured and Predicted Hydrodynamic Damping for a Jack-Up Rig Model

    DEFF Research Database (Denmark)

    Laursen, Thomas; Rohbock, Lars; Jensen, Jørgen Juncher

    1996-01-01

    An extensive set of measurements funded by the EU project Large Scale Facilities Program has been carried out on a model of a jack-up rig at the Danish Hydraulic Institute. The test serieswere conducted by MSC and include determination of base shears and overturning moments in both regular...... methods.In the comparison between the model test results and the theoretical predictions, thehydro-dynamic damping proves to be the most important uncertain parameter. It is shown thata relative large hydrodynamic damping must be assumed in the theoretical calculations in orderto predict the measured...

  4. Jet Exit Rig Six Component Force Balance

    Science.gov (United States)

    Castner, Raymond; Wolter, John; Woike, Mark; Booth, Dennis

    2012-01-01

    A new six axis air balance was delivered to the NASA Glenn Research Center. This air balance has an axial force capability of 800 pounds, primary airflow of 10 pounds per second, and a secondary airflow of 3 pounds per second. Its primary use was for the NASA Glenn Jet Exit Rig, a wind tunnel model used to test both low-speed, and high-speed nozzle concepts in a wind tunnel. This report outlines the installation of the balance in the Jet Exit Rig, and the results from an ASME calibration nozzle with an exit area of 8 square-inches. The results demonstrated the stability of the force balance for axial measurements and the repeatability of measurements better than 0.20 percent.

  5. Challenges associated with pre-border management of biofouling on oil rigs.

    Science.gov (United States)

    Hopkins, Grant A; Forrest, Barrie M

    2010-11-01

    The potential for oil rigs to transport diverse, reef-like communities around the globe makes them high risk vectors for the inadvertent spread of non-indigenous species (NIS). This paper describes two case studies where a suite of pre-border management approaches was applied to semi-submersible drilling rigs. In the first case study, a drilling rig was defouled in-water prior to departure from New Zealand to Australia. Risk mitigation measures were successful in reducing biosecurity risks to the recipient region, but they resulted in the unintentional introduction of the non-indigenous brown mussel (Perna perna) to New Zealand when the rig was defouled in-water by divers. In the second case study, lessons learned from this high-profile incursion resulted in a more structured approach to pre-border management, and this serves as a useful template for future rig transfers. Copyright © 2010 Elsevier Ltd. All rights reserved.

  6. The evaluation of secondary system oxygen-scavenging chemicals using a water-circulating rig

    Energy Technology Data Exchange (ETDEWEB)

    Collins, M.W. [Nuclear Dept., HMS Sultan (United Kingdom)

    2002-07-01

    To assess the efficiency, mode of action and possible by-products of chemical dosing agents, e.g. oxygen scavengers, a circulating water rig was constructed. The rig uses a demineralized water supply as a source of make-up water to fill a recirculating loop of approx. 10 litres volume. The rig pipework is made of polythene with standard off-the shelf pipe fittings and connectors. The following parameters can be measured within the rig: pH and conductivity measured by in-line monitor, dissolved oxygen level, temperature. The system has already been used for some preliminary testing. The following oxygen scavengers have been used for tests: ascorbic acid (vitamin C), N,N-diethyl-hydroxylamine (DEHA), Hydroquinone, hydrazine hydrate and anhydrous sodium sulfite. (authors)

  7. The evaluation of secondary system oxygen-scavenging chemicals using a water-circulating rig

    International Nuclear Information System (INIS)

    Collins, M.W.

    2002-01-01

    To assess the efficiency, mode of action and possible by-products of chemical dosing agents, e.g. oxygen scavengers, a circulating water rig was constructed. The rig uses a demineralized water supply as a source of make-up water to fill a recirculating loop of approx. 10 litres volume. The rig pipework is made of polythene with standard off-the shelf pipe fittings and connectors. The following parameters can be measured within the rig: pH and conductivity measured by in-line monitor, dissolved oxygen level, temperature. The system has already been used for some preliminary testing. The following oxygen scavengers have been used for tests: ascorbic acid (vitamin C), N,N-diethyl-hydroxylamine (DEHA), Hydroquinone, hydrazine hydrate and anhydrous sodium sulfite. (authors)

  8. The laboratory test rig with miniature jet engine to research aviation fuels combustion process

    Directory of Open Access Journals (Sweden)

    Gawron Bartosz

    2015-12-01

    Full Text Available This article presents laboratory test rig with a miniature turbojet engine (MiniJETRig – Miniature Jet Engine Test Rig, that was built in the Air Force Institute of Technology. The test rig has been developed for research and development works aimed at modelling and investigating processes and phenomena occurring in full scale jet engines. In the article construction of a test rig is described, with a brief discussion on the functionality of each of its main components. Additionally examples of measurement results obtained during the realization of the initial tests have been included, presenting the capabilities of the test rig.

  9. Hoisting and rigging manual: Uncontrolled document

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-05-01

    This document is a draft copy of a Hoisting and Rigging Manual for the Department of Energy. The manual is divided into ten chapters. The chapter titles follow: terminology and definitions; operator training and qualification; overhead and gantry cranes; mobile cranes; forklift trucks; hoists; hooks; wire rope, slings, and rigging accessories; construction hoisting and rigging equipment requirements; references.

  10. Endoscopic PIV measurements in a low pressure turbine rig

    Energy Technology Data Exchange (ETDEWEB)

    Kegalj, Martin; Schiffer, Heinz-Peter [Technische Universitaet Darmstadt (Germany). Department of Gas Turbines and Aerospace Propulsion

    2009-10-15

    Particle-Image-Velocimetry (PIV) is a useful way to acquire information about the flow in turbomachinery. Several premises have to be fulfilled to achieve high-quality data, for example, optical access, low vibrations and low reflections. However, not all test facilities comply with these requirements. If there is no optical access to the test area, measurements cannot be performed. The use of borescopic optics is a possible solution to this issue, as the access required is very small. Several different techniques can be used to measure the three components of the velocity vector, one of which is Stereo-PIV. These techniques require either large optical access from several viewing angles or highly complex setups. Orthogonal light sheet orientations in combination with borescopic optics using Planar-PIV can deliver sufficient information about the flow. This study will show the feasibility of such an approach in an enclosed test area, such as the interblade space in a Low-Pressure-Turbine-Rig. The results from PIV will be compared with data collected with conventional techniques, such as the Five-Hole-Probe and the 2-component Hot-Wire-Anemometry. An analysis of time- and phase-averaged data will be performed. (orig.)

  11. A rigged market

    International Nuclear Information System (INIS)

    Thomas, M.

    2000-01-01

    The mobile rig market remains a unique sector of the global upstream oil and gas industry. Big oil is continuing to emerge blinking from the darkness of its recent cash-starved existence to bask in the glory of a resurgent oil price. But the rig sector is once again lagging behind the pace being set by operators as they open up their wallets for new or delayed exploration and production projects. This paper gives statistics on worldwide count and contracts

  12. Endothelial RIG-I activation impairs endothelial function

    International Nuclear Information System (INIS)

    Asdonk, Tobias; Motz, Inga; Werner, Nikos; Coch, Christoph; Barchet, Winfried; Hartmann, Gunther; Nickenig, Georg; Zimmer, Sebastian

    2012-01-01

    Highlights: ► RIG-I activation impairs endothelial function in vivo. ► RIG-I activation alters HCAEC biology in vitro. ► EPC function is affected by RIG-I stimulation in vitro. -- Abstract: Background: Endothelial dysfunction is a crucial part of the chronic inflammatory atherosclerotic process and is mediated by innate and acquired immune mechanisms. Recent studies suggest that pattern recognition receptors (PRR) specialized in immunorecognition of nucleic acids may play an important role in endothelial biology in a proatherogenic manner. Here, we analyzed the impact of endothelial retinoic acid inducible gene I (RIG-I) activation upon vascular endothelial biology. Methods and results: Wild type mice were injected intravenously with 32.5 μg of the RIG-ligand 3pRNA (RNA with triphosphate at the 5′end) or polyA control every other day for 7 days. In 3pRNA-treated mice, endothelium-depended vasodilation was significantly impaired, vascular oxidative stress significantly increased and circulating endothelial microparticle (EMP) numbers significantly elevated compared to controls. To gain further insight in RIG-I dependent endothelial biology, cultured human coronary endothelial cells (HCAEC) and endothelial progenitor cells (EPC) were stimulated in vitro with 3pRNA. Both cells types express RIG-I and react with receptor upregulation upon stimulation. Reactive oxygen species (ROS) formation is enhanced in both cell types, whereas apoptosis and proliferation is not significantly affected in HCAEC. Importantly, HCAEC release significant amounts of proinflammatory cytokines in response to RIG-I stimulation. Conclusion: This study shows that activation of the cytoplasmatic nucleic acid receptor RIG-I leads to endothelial dysfunction. RIG-I induced endothelial damage could therefore be an important pathway in atherogenesis.

  13. Final Hazard Categorization and Auditable Safety Analysis for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2 and 118-H-3 Solid Waste Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    T. J. Rodovsky

    2006-03-01

    This report presents the initial hazard categorization, final hazard categorization and auditable safety analysis for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  14. Endothelial RIG-I activation impairs endothelial function

    Energy Technology Data Exchange (ETDEWEB)

    Asdonk, Tobias, E-mail: tobias.asdonk@ukb.uni-bonn.de [Department of Medicine/Cardiology, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn (Germany); Motz, Inga; Werner, Nikos [Department of Medicine/Cardiology, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn (Germany); Coch, Christoph; Barchet, Winfried; Hartmann, Gunther [Institute for Clinical Chemistry and Clinical Pharmacology, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn (Germany); Nickenig, Georg; Zimmer, Sebastian [Department of Medicine/Cardiology, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn (Germany)

    2012-03-30

    Highlights: Black-Right-Pointing-Pointer RIG-I activation impairs endothelial function in vivo. Black-Right-Pointing-Pointer RIG-I activation alters HCAEC biology in vitro. Black-Right-Pointing-Pointer EPC function is affected by RIG-I stimulation in vitro. -- Abstract: Background: Endothelial dysfunction is a crucial part of the chronic inflammatory atherosclerotic process and is mediated by innate and acquired immune mechanisms. Recent studies suggest that pattern recognition receptors (PRR) specialized in immunorecognition of nucleic acids may play an important role in endothelial biology in a proatherogenic manner. Here, we analyzed the impact of endothelial retinoic acid inducible gene I (RIG-I) activation upon vascular endothelial biology. Methods and results: Wild type mice were injected intravenously with 32.5 {mu}g of the RIG-ligand 3pRNA (RNA with triphosphate at the 5 Prime end) or polyA control every other day for 7 days. In 3pRNA-treated mice, endothelium-depended vasodilation was significantly impaired, vascular oxidative stress significantly increased and circulating endothelial microparticle (EMP) numbers significantly elevated compared to controls. To gain further insight in RIG-I dependent endothelial biology, cultured human coronary endothelial cells (HCAEC) and endothelial progenitor cells (EPC) were stimulated in vitro with 3pRNA. Both cells types express RIG-I and react with receptor upregulation upon stimulation. Reactive oxygen species (ROS) formation is enhanced in both cell types, whereas apoptosis and proliferation is not significantly affected in HCAEC. Importantly, HCAEC release significant amounts of proinflammatory cytokines in response to RIG-I stimulation. Conclusion: This study shows that activation of the cytoplasmatic nucleic acid receptor RIG-I leads to endothelial dysfunction. RIG-I induced endothelial damage could therefore be an important pathway in atherogenesis.

  15. Technology trends, energy prices affect worldwide rig activity

    International Nuclear Information System (INIS)

    Rappold, K.

    1995-01-01

    The major worldwide offshore rig markets have improved slightly this year, while the onshore markets generally lagged slightly. Offshore rig utilization rates have remained strong worldwide, with some areas reaching nearly 100%. Total worldwide offshore rig (jack ups, semisubmersible, drillships, submersibles, and barges) utilization was about 86%. Offshore drilling activity is driven primarily by oil and natural gas price expectations. Natural gas prices tend to drive North American offshore drilling activity, including the shallow waters in the Gulf of Mexico. International offshore drilling activity and deepwater projects in the Gulf of Mexico are more closely tied to oil prices. The paper discusses US rig count, directional drilling activity, jack up rig demand, semisubmersibles demand, rig replacement costs, and new construction

  16. Rigged Hilbert spaces for chaotic dynamical systems

    International Nuclear Information System (INIS)

    Suchanecki, Z.; Antoniou, I.; Bandtlow, O.F.

    1996-01-01

    We consider the problem of rigging for the Koopman operators of the Renyi and the baker maps. We show that the rigged Hilbert space for the Renyi maps has some of the properties of a strict inductive limit and give a detailed description of the rigged Hilbert space for the baker maps. copyright 1996 American Institute of Physics

  17. Learning Inverse Rig Mappings by Nonlinear Regression.

    Science.gov (United States)

    Holden, Daniel; Saito, Jun; Komura, Taku

    2017-03-01

    We present a framework to design inverse rig-functions-functions that map low level representations of a character's pose such as joint positions or surface geometry to the representation used by animators called the animation rig. Animators design scenes using an animation rig, a framework widely adopted in animation production which allows animators to design character poses and geometry via intuitive parameters and interfaces. Yet most state-of-the-art computer animation techniques control characters through raw, low level representations such as joint angles, joint positions, or vertex coordinates. This difference often stops the adoption of state-of-the-art techniques in animation production. Our framework solves this issue by learning a mapping between the low level representations of the pose and the animation rig. We use nonlinear regression techniques, learning from example animation sequences designed by the animators. When new motions are provided in the skeleton space, the learned mapping is used to estimate the rig controls that reproduce such a motion. We introduce two nonlinear functions for producing such a mapping: Gaussian process regression and feedforward neural networks. The appropriate solution depends on the nature of the rig and the amount of data available for training. We show our framework applied to various examples including articulated biped characters, quadruped characters, facial animation rigs, and deformable characters. With our system, animators have the freedom to apply any motion synthesis algorithm to arbitrary rigging and animation pipelines for immediate editing. This greatly improves the productivity of 3D animation, while retaining the flexibility and creativity of artistic input.

  18. Design and Demonstration of a Test-Rig for Static Performance-Studies of Permanent Magnet Couplings

    DEFF Research Database (Denmark)

    Högberg, Stig; Jensen, Bogi Bech; Bendixen, Flemming Buus

    2013-01-01

    The design and construction of an easy-to-use test-rig for permanent magnet couplings is presented. Static torque of permanent magnet couplings as a function of angular displacement is measured of permanent magnet couplings through an semi-automated test system. The test-rig is capable of measuring...

  19. Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG.

    Science.gov (United States)

    Bharti, Omesh Kumar; Madhusudana, Shampur Narayan; Wilde, Henry

    2017-04-03

    An increasing number of dog bite victims were being presented to public hospitals in Himachal Pradesh in 2014 amidst virtual non availability of any rabies immunoglobulin (RIG). Only a small quantity of equine rabies immunoglobulin (eRIG) was available from the government owned Central Research Institute (CRI) Kasauli. This available eRIG was used in 269 patients as an emergency response and only for local infiltration of severe bite wounds by suspected rabid dogs. This was followed by rabies vaccination, using the WHO approved intra-dermal Thai Red Cross Society vaccination schedule. A subgroup of 26 patients were later identified who had been severely bitten by laboratory confirmed rabid dogs. They were followed for more than one year and all were found to be alive.

  20. ROLLER RIG TESTING AT THE CZECH TECHNICAL UNIVERSITY

    Directory of Open Access Journals (Sweden)

    J. Kalivoda

    2016-08-01

    Full Text Available Purpose. Although the advancements in computer simulation technology have paved way to provide very reliable simulation results, track tests still play an essential role during the process of development and homologation of any railway vehicle. On the other hand, track tests depend on weather conditions, are difficult to organize and are not suitable for testing vehicles in critical situations. On a roller rig, the tested vehicle is longitudinally fixed and a track is replaced by rotating rollers. Such device offer testing of railway vehicle running dynamics in safe and stable laboratory environment. The purpose of an article is to investigate and describe roller rig testing at the Czech technical university in Prague (CTU. Methodology. In the paper it is shown the history of development of the scaled CTU roller rig from the earlier stages until the current projects for which the CTU roller rig is utilized for. The current design of the experimental bogie, roller rig, sensors instrumentation and types of experiments conducted at the CTU roller rig are described in more detail. Findings. Although the differences in vehicle behaviour on a track and a scaled model on a roller rig are not negligible, scaled roller rig experiments are found as a relatively inexpensive way for verification and demonstration of computer simulations results. They are especially useful for verification of multibody system simulations (MBS of entirely new running gear concepts. Originality. The CTU roller rig is currently used for the experiments with active controlled wheelset guidance. According to simulations results published in many papers such systems offer, in principle, better performance compared to conventional passive vehicles. However, utilization and testing of active controlled wheelset guidance on vehicles is still rare. CTU roller rig serves as a tool to verify computer simulations and demonstrate benefits of active wheelset guidance. Practical value

  1. Measuring deformation of Fuel pin in a Nuclear Fuel Test Rig

    Energy Technology Data Exchange (ETDEWEB)

    Heo, S. H.; Yang, T. H.; Hong, J. T.; Joung, C. Y.; Ahn, S. H.; Jang, S. Y.; Kim, J. H. [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    In this study, an LVDT core for measuring the longitudinal displacement of fuel pellets and clad was designed and produced. A signal processing method for the prepared core was investigated. The Nuclear Fuel Test Rig is used to observe changes in the characteristics of the fuel according to the neutron irradiation at HANARO (High-flux Advanced Neutron Application Reactor), which is a research reactor. Which are the strain and internal temperature of the irradiated nuclear fuel and the internal pressure of fuel due to fission gas, the characteristics of the fuel are measured using various sensors such as a thermocouple, SPND and LVDT. In this study, two shaped LVDT (Linear Variable Differential Transformer) cores for displacement measurements were designed and manufactured in order to measure the displacement of a fuel pellet and cladding tube using LVDT sensors for measuring electrical signals by converting the physical variation such as the force and displacement into a linear motion. In addition, signals from the manufactured LVDT sensor were collected and calibrated. Moreover, a method for obtaining the displacement in the core according to the sensing signal was planned. A derived equation can used to predict the change in the position of core. A following study should be conducted to test the output signal and real variation of out-pile system. For further work, a performance verification is required for an in-pile irradiation test.

  2. Rig supervisors

    International Nuclear Information System (INIS)

    Nordt, D.P.; Stone, M.S.

    1992-01-01

    This paper helps prepare the inexperienced rig supervisor to manage a drilling operation. It outlines operational-knowledge requirements and optimization concepts for improving drilling performance and lowering drilling costs. It gives guidelines on safety and environmental responsibilities, and provides recommendations on work tools, leadership, and communication

  3. Experimental rigs for MHD studies

    International Nuclear Information System (INIS)

    Venkataramani, N.; Jayakumar, R.; Iyer, D.R.; Dixit, N.S.

    1976-01-01

    An MHD experimental rig is a miniature MHD installation consisting of basic equipments necessary for specific investigations. Some of the experimental rigs used in the investigations being carried out at the Bhabha Atomic Research Centre, Bombay (India) are dealt with. The experiments included diagnostics and evaluation of materials in seeded combustion plasmas and argon plasmas. The design specifications, schematics and some of the results of the investigations are also mentioned. (author)

  4. 29 CFR 1918.54 - Rigging gear.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Rigging gear. 1918.54 Section 1918.54 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Vessel's Cargo Handling Gear § 1918.54 Rigging gear. (a... other alternate device shall be provided to allow trimming of the gear and to prevent employees from...

  5. A reciprocating pin-on-plate test-rig for studying friction materials for holding brakes

    DEFF Research Database (Denmark)

    Poulios, Konstantinos; Drago, Nicola; Klit, Peder

    2014-01-01

    -on-plate test-rig for studying the evolution of wear by monitoring the pin height reduction using Eddy-current proximity sensors is presented. Moreover, a new mechanism for recording the friction force is suggested. Apart from the design of the test-rig, friction force and wear rate measurements for two...

  6. A novel test rig to investigate under-platform damper dynamics

    Science.gov (United States)

    Botto, Daniele; Umer, Muhammad

    2018-02-01

    In the field of turbomachinery, vibration amplitude is often reduced by dissipating the kinetic energy of the blades with devices that utilize dry friction. Under-platform dampers, for example, are often placed in the underside of two consecutive turbine blades. Dampers are kept in contact with the under-platform of the respective blades by means of the centrifugal force. If the damper is well designed, vibration of blades instigate a relative motion between the under-platform and the damper. A friction force, that is a non-conservative force, arises in the contact and partly dissipates the vibration energy. Several contact models are available in the literature to simulate the contact between the damper and the under-platform. However, the actual dynamics of the blade-damper interaction have not fully understood yet. Several test rigs have been previously developed to experimentally investigate the performance of under-platform dampers. The majority of these experimental setups aim to evaluate the overall damper efficiency in terms of reduction in response amplitude of the blade for a given exciting force that simulates the aerodynamic loads. Unfortunately, the experimental data acquired on the blade dynamics do not provide enough information to understand the damper dynamics. Therefore, the uncertainty on the damper behavior remains a big issue. In this work, a novel experimental test rig has been developed to extensively investigate the damper dynamic behavior. A single replaceable blade is clamped in the rig with a specific clamping device. With this device the blade root is pressed against a groove machined in the test rig. The pushing force is controllable and measurable, to better simulate the actual centrifugal load acting on the blade. Two dampers, one on each side of the blade, are in contact with the blade under-platforms and with platforms on force measuring supports. These supports have been specifically designed to measure the contact forces on the

  7. ESTUDO COMPARATIVO DAS ANASTOMOSES ARTERIAIS COM FIO ABSORVÍVEL E NÃO ABSORVÍVEL EM SUÍNOS EM CRESCIMENTO

    Directory of Open Access Journals (Sweden)

    IBRAHIM ELIAS KALLÁS

    1998-07-01

    Full Text Available O objetivo deste trabalho foi observar a evolução, após 12 meses, das artérias anastomosadas com polipropileno e com fios de poliglactina 910, nos suínos em fase de crescimento. A amostra foi composta por 16 fêmeas da raça Landrace, distribuídas em dois grupos : A e B. Os animais devidamente pesados, foram submetidos a secção transversal da aorta abdominalis, abaixo das arteriae renalis dextra et sinistra,que após a medida dos diâmetros internos foram anastomosadas com os fios correspondentes, mediante suturas contínuas. Após um ano os animais foram submetidos à eutanásia e novas medidas realizadas. Em ambos os grupos ficou evidenciado que pesos maiores estão relacionados a diâmetros maiores das artérias. Houve aumento médio de 1027,5 % no peso final dos animais do grupo A e 1242,9 % nos animais do grupo B. Houve aumento médio de 98,6 % no diâmetro final das artérias dos animais do Grupo A e de 102,7% nas animais do grupo B. Para a análise estatística valeu-se dos testes de WILCOXON e MANN-WHITNEY, com cálculo de D %. Os fios de polipropileno permaneceram nas artérias dos animais do grupo A sendo identificados de duas formas: rotos ou em alça, mas sempre fazendo proeminência na luz arterial. Os fios de poliglactina 910 não foram identificados. Concluiu-se que o fios de polipropileno e de poliglactina 910 permitem o crescimento das artérias ao nível das anastomoses término-terminais na aorta abdominalis de suínos.The aim of this study is to observe polypropylene and polyglactine 910 anastomosis, in growing pigs after twelve months. Sixteen female "Landrace" piglets were distributed into two groups : A and B. After being weighed, the animals underwent aorta abdominalis transversal section under arteria renalis dextra and sinistra, diameter measurement, and anastomosis in continuous suture with the above mentioned threads. One year later, the animals were euthanized and new measurement was performed. In both groups

  8. Endurance test of DUPIC irradiation test rig-003

    Energy Technology Data Exchange (ETDEWEB)

    Moon, J.S; Yang, M.S.; Lee, C.Y.; Ryu, J.S.; Jeon, H.G

    2001-04-01

    This report presents the pressure drop, vibration and endurance test results for DUPIC Irradiation Test Rig-003 which was design and fabricated by KAERI. From the pressure drop and vibration test results, it is verified that DUPIC Irradiation Test Rig-003 satisfied the limit conditions of HANARO. And, remarkable wear is not observed in DUPIC Irradiation Test Rig-003 during 40 endurance test days.

  9. A new generation drilling rig: hydraulically powered and computer controlled

    Energy Technology Data Exchange (ETDEWEB)

    Laurent, M.; Angman, P.; Oveson, D. [Tesco Corp., Calgary, AB, (Canada)

    1999-11-01

    Development, testing and operation of a new generation of hydraulically powered and computer controlled drilling rig that incorporates a number of features that enhance functionality and productivity, is described. The rig features modular construction, a large heated common drilling machinery room, permanently-mounted draw works which, along with the permanently installed top drive, significantly reduces rig-up/rig-down time. Also featured are closed and open hydraulic systems and a unique hydraulic distribution manifold. All functions are controlled through a programmable logic controller (PLC), providing almost unlimited interlocks and calculations to increase rig safety and efficiency. Simplified diagnostic routines, remote monitoring and troubleshooting are also part of the system. To date, two rigs are in operation. Performance of both rigs has been rated as `very good`. Little or no operational problems have been experienced; downtime has averaged 0.61 per cent since August 1998 when the the first of the two rigs went into operation. The most important future application for this rig is for use with the casing drilling process which eliminates the need for drill pipe and tripping. It also reduces the drilling time lost due to unscheduled events such as reaming, fishing and taking kicks while tripping. 1 tab., 6 figs.

  10. Advanced control strategies for a drill rig

    International Nuclear Information System (INIS)

    Banerjee, A.; Hiller, M.; Fink, B.

    1996-01-01

    The construction of tunnels is usually undertaken using a combination of blasting and drilling to achieve rock excavation. Easy handling and high accuracy, and thus greater efficiency, in drilling rigs is an essential ingredient of successful competition in the market place. This article describes a cartesian control concept used for a twin boom drill rig. This simplifies the handling of a drilling boom, reduces the duration of a working cycle and increases security. A remote control system has been added to the drill rig to support the operator working in complicated environments. (UK)

  11. Body Language Advanced 3D Character Rigging

    CERN Document Server

    Allen, Eric; Fong, Jared; Sidwell, Adam G

    2011-01-01

    Whether you're a professional Character TD or just like to create 3D characters, this detailed guide reveals the techniques you need to create sophisticated 3D character rigs that range from basic to breathtaking. Packed with step-by-step instructions and full-color illustrations, Body Language walks you through rigging techniques for all the body parts to help you create realistic and believable movements in every character you design. You'll learn advanced rigging concepts that involve MEL scripting and advanced deformation techniques and even how to set up a character pipeline.

  12. Gulf of Mexico rig activity up, international lags

    International Nuclear Information System (INIS)

    Rappold, K.

    1994-01-01

    Demand for jack up and semisubmersible rigs has improved in the Gulf of Mexico following a decline in activity earlier this year. International drilling activity, however, has shown slight declines in several regions. Relatively firm natural gas prices have helped buoy rig activity in North America. Rig day rates have not followed suit, mainly because of the influx of rigs from weaker international markets. Day rates in the US may not increase until international activity picks up and the world-wide drilling market tightens. Oil prices have hit almost $20/bbl, mainly because of the recent oil worker' strike in Nigeria and good demand. Natural gas prices in the US have hovered around $2.00/MMBTU, and many industry analysts expect gas prices to remain strong over the next few years. This paper gives data on drilling rig counts and crude oil and gas prices in the Gulf of Mexico and onshore

  13. Viral Pseudo Enzymes Activate RIG-I via Deamidation to Evade Cytokine Production

    Science.gov (United States)

    He, Shanping; Zhao, Jun; Song, Shanshan; He, Xiaojing; Minassian, Arlet; Zhou, Yu; Zhang, Junjie; Brulois, Kevin; Wang, Yuqi; Cabo, Jackson; Zandi, Ebrahim; Liang, Chengyu; Jung, Jae U; Zhang, Xuewu; Feng, Pinghui

    2015-01-01

    SUMMARY RIG-I is a pattern recognition receptor that senses viral RNA and is crucial for host innate immune defense. Here we describe a mechanism of RIG-I activation through amidotransferase-mediated deamidation. We show that viral homologues of phosphoribosylformyglycinamide synthase (PFAS), although lacking intrinsic enzyme activity, recruit cellular PFAS to deamidate and activate RIG-I. Accordingly, depletion and biochemical inhibition of PFAS impair RIG-I deamidation and concomitant activation. Purified PFAS and viral homologue thereof deamidate RIG-I in vitro. Ultimately, herpesvirus hijacks activated RIG-I to avoid antiviral cytokine production; loss of RIG-I or inhibition of RIG-I deamidation results in elevated cytokine production. Together, these findings demonstrate a surprising mechanism of RIG-I activation that is mediated by an enzyme. PMID:25752576

  14. Cooling Effectiveness Measurements for Air Film Cooling of Thermal Barrier Coated Surfaces in a Burner Rig Environment Using Phosphor Thermometry

    Science.gov (United States)

    Eldridge, Jeffrey I.; Shyam, Vikram; Wroblewski, Adam C.; Zhu, Dongming; Cuy, Michael D.; Wolfe, Douglas E.

    2016-01-01

    While the effects of thermal barrier coating (TBC) thermal protection and air film cooling effectiveness are usually studied separately, their contributions to combined cooling effectiveness are interdependent and are not simply additive. Therefore, combined cooling effectiveness must be measured to achieve an optimum balance between TBC thermal protection and air film cooling. In this investigation, surface temperature mapping was performed using recently developed Cr-doped GdAlO3 phosphor thermometry. Measurements were performed in the NASA GRC Mach 0.3 burner rig on a TBC-coated plate using a scaled up cooling hole geometry where both the mainstream hot gas temperature and the blowing ratio were varied. Procedures for surface temperature and cooling effectiveness mapping of the air film-cooled TBC-coated surface are described. Applications are also shown for an engine component in both the burner rig test environment as well as an engine afterburner environment. The effects of thermal background radiation and flame chemiluminescence on the measurements are investigated, and advantages of this method over infrared thermography as well as the limitations of this method for studying air film cooling are discussed.

  15. Mortality prediction to hospitalized patients with influenza pneumonia: PO2 /FiO2 combined lymphocyte count is the answer.

    Science.gov (United States)

    Shi, Shu Jing; Li, Hui; Liu, Meng; Liu, Ying Mei; Zhou, Fei; Liu, Bo; Qu, Jiu Xin; Cao, Bin

    2017-05-01

    Community-acquired pneumonia (CAP) severity scores perform well in predicting mortality of CAP patients, but their applicability in influenza pneumonia is powerless. The aim of our research was to test the efficiency of PO 2 /FiO 2 and CAP severity scores in predicting mortality and intensive care unit (ICU) admission with influenza pneumonia patients. We reviewed all patients with positive influenza virus RNA detection in Beijing Chao-Yang Hospital during the 2009-2014 influenza seasons. Outpatients, inpatients with no pneumonia and incomplete data were excluded. We used receiver operating characteristic curves (ROCs) to verify the accuracy of severity scores or indices as mortality predictors in the study patients. Among 170 hospitalized patients with influenza pneumonia, 30 (17.6%) died. Among those who were classified as low-risk (predicted mortality 0.1%-2.1%) by pneumonia severity index (PSI) or confusion, urea, respiratory rate, blood pressure, age ≥65 year (CURB-65), the actual mortality ranged from 5.9 to 22.1%. Multivariate logistic regression indicated that hypoxia (PO 2 /FiO 2  ≤ 250) and lymphopenia (peripheral blood lymphocyte count pneumonia confirmed a similar pattern and PO 2 /FiO 2 combined lymphocyte count was also the best predictor for predicting ICU admission. In conclusion, we found that PO 2 /FiO 2 combined lymphocyte count is simple and reliable predictor of hospitalized patients with influenza pneumonia in predicting mortality and ICU admission. When PO 2 /FiO 2  ≤ 250 or peripheral blood lymphocyte count pneumonia. © 2015 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd.

  16. Customization creates more efficient, cleaner rigs

    Energy Technology Data Exchange (ETDEWEB)

    Budd, G.

    2002-08-01

    Technological advances in drilling equipment are essential to improving efficiency in the oilpatch; getting the technological upper hand on the competition is no less important for drilling equipment manufacturers than for actors in other sectors of the industry. While off-the-shelf uniformity that reduces unit cost has been the trend in fabricating field gas compression modules, custom manufacturing has become very popular in the rig manufacturing sector. Examples from Crown Energy Technologies and Tesco Corporation, both of Calgary, Aecon Industrial's Edmonton operations, PCL Industrial Construction Ltd of Nisku, and Toromont Process Systems of Houston and Calgary are described to illustrate the widespread demand for customized drilling rigs, including the growing preference for electric drives. Top drive systems, as opposed to rotary drives also have become very popular; six out of ten rigs are sold with electric top drives today compared with fewer than 10 rigs a decade ago. At the same time, Tesco has recently signed a deal with Conoco Inc to construct three revolutionary drilling rigs using Tesco's proprietary Casing Drilling Technology, which uses standard oilfield casing instead of drill pipe, allowing operators to simultaneously drill, case and evaluate oil and gas wells. Aecon and PCL Industrial Construction have had much demand for customized spools and modules particularly from the oil sands industry, while Toromont Process Systems is also expanding its Calgary facilities to meet the demand for its dual gas compression equipment used by power stations for gas compression and co-generation, natural gas refrigeration and specialty gas processing.

  17. Deep water challenges for drilling rig design

    Energy Technology Data Exchange (ETDEWEB)

    Roth, M [Transocean Sedco Forex, Houston, TX (United States)

    2001-07-01

    Drilling rigs designed for deep water must meet specific design considerations for harsh environments. The early lessons for rig design came from experiences in the North Sea. Rig efficiency and safety considerations must include structural integrity, isolated/redundant ballast controls, triple redundant DP systems, enclosed heated work spaces, and automated equipment such as bridge cranes, pipe handling gear, offline capabilities, subsea tree handling, and computerized drill floors. All components must be designed to harmonize man and machine. Some challenges which are unique to Eastern Canada include frequent storms and fog, cold temperature, icebergs, rig ice, and difficult logistics. This power point presentation described station keeping and mooring issues in terms of dynamic positioning issues. The environmental influence on riser management during forced disconnects was also described. Design issues for connected deep water risers must insure elastic stability, and control deflected shape. The design must also keep stresses within acceptable limits. Codes and standards for stress limits, flex joints and tension were also presented. tabs., figs.

  18. Design and construction of a point-contact spectroscopy rig with lateral scanning capability

    Energy Technology Data Exchange (ETDEWEB)

    Tortello, M. [Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Torino 10129 (Italy); Park, W. K., E-mail: wkpark@illinois.edu; Ascencio, C. O.; Saraf, P.; Greene, L. H. [Department of Physics and Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States)

    2016-06-15

    The design and realization of a cryogenic rig for point-contact spectroscopy measurements in the needle-anvil configuration is presented. Thanks to the use of two piezoelectric nano-positioners, the tip can move along the vertical (z) and horizontal (x) direction and thus the rig is suitable to probe different regions of a sample in situ. Moreover, it can also form double point-contacts on different facets of a single crystal for achieving, e.g., an interferometer configuration for phase-sensitive measurements. For the later purpose, the sample holder can also host a Helmholtz coil for applying a small transverse magnetic field to the junction. A semi-rigid coaxial cable can be easily added for studying the behavior of Josephson junctions under microwave irradiation. The rig can be detached from the probe and thus used with different cryostats. The performance of this new probe has been tested in a Quantum Design PPMS system by conducting point-contact Andreev reflection measurements on Nb thin films over large areas as a function of temperature and magnetic field.

  19. Innovative technology for a cost-effective land rig

    Energy Technology Data Exchange (ETDEWEB)

    Mehra, S.; Bryce, T.

    1996-05-01

    Sedco Forex has recently completed a new land drilling rig, currently deployed in Gabon, that integrates well construction activities with multiskilling to create cost savings across the board in drilling operations. Historically, operators have produced a comprehensive tender package specifying strictly the type and size of individual rig components and the number of personnel required to drill. In this case, the drilling contractor provides a fit-for-purpose rig, consistent with field location, well profile, operator`s priorities, and local constraints.

  20. Innovative technology for a cost-effective land rig

    International Nuclear Information System (INIS)

    Mehra, S.; Bryce, T.

    1996-01-01

    Sedco Forex has recently completed a new land drilling rig, currently deployed in Gabon, that integrates well construction activities with multiskilling to create cost savings across the board in drilling operations. Historically, operators have produced a comprehensive tender package specifying strictly the type and size of individual rig components and the number of personnel required to drill. In this case, the drilling contractor provides a fit-for-purpose rig, consistent with field location, well profile, operator's priorities, and local constraints

  1. Computer gaming comes to service rig training

    Energy Technology Data Exchange (ETDEWEB)

    Mowers, J.

    2007-05-15

    This article addressed the challenge of providing service rig workers with a good understanding of the tasks and risks involved in the job before they even step out into the field. The product, SimuLynx was presented. SimuLynx is based on video and gaming technology to immerse the user in the service rig work environment with other crew members. The user tries to perform the different steps of a junior floorhand's job while a coach gives directions. The article discussed how the system works. For example, when faced with a task, the user chooses from several options. The coach informs the virtual junior floorhand if the decision was right or wrong. He will also give warnings and let the user realize the consequences of a wrong action. The benefits of the system were also presented. For example, instead of 30 days of on-the-job training, an employee may only need several days after going through the program. Other benefits that were reviewed included reduced accident risk-levels for new workers; higher rig efficiency; and, lower training costs. In addition, a potential recruit can decide if the job is right for him before signing up for an expensive course or starting off with a service rig company. As well, the rig company can decide if someone is suitable before hiring that person. 3 figs.

  2. An in situ thermo-mechanical rig for lattice strain measurement during creep using neutron diffraction

    Science.gov (United States)

    Wang, Y. Q.; Kabra, S.; Zhang, S. Y.; Truman, C. E.; Smith, D. J.

    2018-05-01

    A long-term high-temperature testing stress rig has been designed and fabricated for performing in situ neutron diffraction tests at the ENGIN-X beamline, ISIS facility in the UK. It is capable of subjecting metals to high temperatures up to 800 °C and uniaxial loading under different boundary conditions including constant load, constant strain, and elastic follow-up, each with minimum of external control. Samples are held horizontally between grips and connected to a rigid rig frame, a soft aluminium bar, and a stepper motor with forces up to 20 kN. A new three zone split electrical resistance furnace which generates a stable and uniform heat atmosphere over 200 mm length was used to heat the samples. An 8 mm diameter port at 45° to the centre of the furnace was made in order to allow the neutron beam through the furnace to illuminate the sample. The entire instrument is mounted on the positioner at ENGIN-X and has the potential ability to operate continuously while being moved in and out of the neutron diffraction beam. The performance of the rig has been demonstrated by tracking the evolution of lattice strains in type 316H stainless steel under elastic follow-up control at 550 °C.

  3. Peak Pressures and PaO2/FiO2 Ratios Are Associated With Adverse Outcomes in Patients on Mechanical Ventilators.

    Science.gov (United States)

    Whiting, Jeremy; Edriss, Hawa; Yang, Shengping; Nugent, Kenneth

    2016-06-01

    Patients requiring mechanical ventilation can have complications related to their underlying diseases and hospital-related events. It is possible that easily obtained information early in the course of mechanical ventilation can provide information about important outcomes. Medical records from 281 episodes of mechanical ventilation in the medical intensive care unit were reviewed to collect information on patient demographics, admitting diagnoses, laboratory tests, duration of mechanical ventilation, the development of ventilator-associated events and mortality. Ventilator pressures from day 2 were analyzed for this study. Most patients (72.7%) were ≥50 years, 53.8% were men and 66.3% had a body mass index (BMI) ≥ 25kg/m(2).The mean Acute Physiology and Chronic Healthy Evaluation II score was 13.6 ± 5.9. The median initial PaO2/FiO2 was 240 with interquartile range of 177-414. The median duration of ventilation was 4 days (interquartile range: 2-9 days). A PaO2/FiO2 ratio 500, and a BMI > 30kg/m(2) was associated with decreased mortality compared with normal BMIs. A PaO2/FiO2 ratio 30kg/m(2) were all associated with having a ventilator-associated event. There was a positive correlation between peak pressure (day 2) and the duration of ventilation (r = 0.263, P = 0.007). Easily available information collected on day 2 of mechanical ventilation can help identify patients at risk for poor outcomes, including the duration of mechanical ventilation, the development of ventilator-associated complications and mortality. Prospective studies measuring peak pressures are needed to evaluate the utility of this simple measurement in the management of patients requiring mechanical ventilation. Published by Elsevier Inc.

  4. The Hydraulic Test Report for Non-instrumented Irradiation Test Rig of DUO-Cooled Annular Pellet

    International Nuclear Information System (INIS)

    Kim, Dae Ho; Lee, Kang Hee; Shin, Chang Hwan; Yang, Yong Sik; Kim, Sun Ki; Bang, Je Geon; Song, Kun Woo

    2007-08-01

    This report presents the results of pressure drop test and vibration test for non-instrumented rig of Advanced PWR DUO-Fuel Annular Pellet which were designed and fabricated by KAERI. From the pressure drop test results, it is noted that the flow velocity across the non-instrumented rig of Advanced PWR DUO-Fuel Annular Pellet corresponding to the pressure drop of 200 kPa is measured to be about 8.30 kg/sec. Vibration frequency results for the non-instrumented rig at the pump spin frequency ranges from 19.0 to 32.0 Hz, RMS(Root Mean Square) displacement for the non-instrumented rig of Advanced PWR DUO-Fuel Annular Pellet is less than 7.25 m, and the maximum displacement is less than 31.27 μm. This test was performed at the FIVPET facility

  5. A compact internal drum test rig for measurements of rolling contact forces between a single tread block and a substrate

    NARCIS (Netherlands)

    Lundberg, O.E.; Kari, L.; Lopez Arteaga, I.

    2017-01-01

    A novel test rig design is presented which enables detailed studies of the three force components generated in the impact and release phase of rolling contact between a tyre tread block and a substrate. The design of the compact internal drum test rig provides realistic impact and release angles for

  6. A Built for Purpose Micro-Hole Coiled Tubing Rig (MCTR)

    Energy Technology Data Exchange (ETDEWEB)

    Bart Patton

    2007-09-30

    This report will serve as the final report on the work performed from the contract period October 2005 thru April 2007. The project 'A Built for Purpose Microhole Coiled Tubing Rig (MCTR)' purpose was to upgrade an existing state-of-the-art Coiled Tubing Drilling Rig to a Microhole Coiled Tubing Rig (MCTR) capable of meeting the specifications and tasks of the Department of Energy. The individual tasks outlined to meet the Department of Energy's specifications are: (1) Concept and development of lubricator and tool deployment system; (2) Concept and development of process control and data acquisition; (3) Concept and development of safety and efficiency improvements; and (4) Final unit integration and testing. The end result of the MCTR upgrade has produced a unit capable of meeting the following requirements: (1) Capable of handling 1-inch through 2-3/8-inch coiled tubing (Currently dressed for 2-3/8-inch coiled tubing and capable of running up to 3-1/2-inch coiled tubing); (2) Capable of drilling and casing surface, intermediate, production and liner hole intervals; (3) Capable of drilling with coiled tubing and has all controls and installation piping for a top drive; (4) Rig is capable of running 7-5/8-inch range 2 casing; and (5) Capable of drilling 5,000 ft true vertical depth (TVD) and 6,000 ft true measured depth (TMD).

  7. The role of the rigged Hilbert space in quantum mechanics

    International Nuclear Information System (INIS)

    Madrid, Rafael de la

    2005-01-01

    There is compelling evidence that, when a continuous spectrum is present, the natural mathematical setting for quantum mechanics is the rigged Hilbert space rather than just the Hilbert space. In particular, Dirac's braket formalism is fully implemented by the rigged Hilbert space rather than just by the Hilbert space. In this paper, we provide a pedestrian introduction to the role the rigged Hilbert space plays in quantum mechanics, by way of a simple, exactly solvable example. The procedure will be constructive and based on a recent publication. We also provide a thorough discussion on the physical significance of the rigged Hilbert space

  8. A calibration rig for multi-component internal strain gauge balance using the new design-of-experiment (DOE) approach

    Science.gov (United States)

    Nouri, N. M.; Mostafapour, K.; Kamran, M.

    2018-02-01

    In a closed water-tunnel circuit, the multi-component strain gauge force and moment sensor (also known as balance) are generally used to measure hydrodynamic forces and moments acting on scaled models. These balances are periodically calibrated by static loading. Their performance and accuracy depend significantly on the rig and the method of calibration. In this research, a new calibration rig was designed and constructed to calibrate multi-component internal strain gauge balances. The calibration rig has six degrees of freedom and six different component-loading structures that can be applied separately and synchronously. The system was designed based on the applicability of formal experimental design techniques, using gravity for balance loading and balance positioning and alignment relative to gravity. To evaluate the calibration rig, a six-component internal balance developed by Iran University of Science and Technology was calibrated using response surface methodology. According to the results, calibration rig met all design criteria. This rig provides the means by which various methods of formal experimental design techniques can be implemented. The simplicity of the rig saves time and money in the design of experiments and in balance calibration while simultaneously increasing the accuracy of these activities.

  9. 21. century drilling rigs -- Tesco introduces new modular design

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1998-10-01

    Development of a modular, hydraulic, self-elevating drilling rig, dubbed the `21. century drilling rig` was announced by the Tesco Corporation. The rig equipment is housed in 8 by 20 by 8.5 feet high sea containers that can be handled by a 20-ton oilfield picker. These containers, weighing about 15,000 to 20,000 pounds on average, eliminate the need for heavy and bulky standard oilfield skid buildings, besides avoiding costly over-width and over-weight permits. The containers can be easily shipped around the world at a fraction of the cost of shipping standard oilfield skid buildings. Time for shipping on land is comparable to conventional rigs, but with the added advantage of smaller and lighter loads, promising fewer transportation problems during spring breakup. Tesco also designed and built an 85-foot long, triple-axle, 24-wheel catwalk trailer to transport the top drive, drawworks and double telescoping mast as one unit. Another novel characteristic of this unit is that the hydraulic system is capable of selectable distribution of power to the main functions such as the top drive, drawworks, or mud pump, similar to the electric SCR rig. The rig also features a computerized control system managed by programmable logic controllers. The split crown and split block to facilitate wireline work, are other innovative features worthy of note.

  10. Statistikeren skiftede spor som 49-årig

    DEFF Research Database (Denmark)

    Sølund, Sune; Rootzén, Helle

    2010-01-01

    En uddannelse til coach har ændret Helle Rototzens liv. Som 49-årig forlod hun et forskerliv på deltid til fordel for en karriere som DTU's eneste kvindelige institutdirektør.......En uddannelse til coach har ændret Helle Rototzens liv. Som 49-årig forlod hun et forskerliv på deltid til fordel for en karriere som DTU's eneste kvindelige institutdirektør....

  11. Minimal disturbance : Ensign's ADR-1000-CT rig aimed at CBM market

    International Nuclear Information System (INIS)

    Roche, P.

    2005-01-01

    Ensign Resource Services Group Inc. has recently designed a light, mobile rig aimed at Western Canada's coalbed methane (CBM) market. With a 1000 metre depth rating, the automated ADR-1000-CT rig can drill with either jointed pipe or 3 and a half-inch coil. Tractor units are used to move the rig to avoid the extra traffic generated by third-party trucks. The rig's self-levelling capability creates less environmental disturbance. Each component works on sites with as much as 2 metres difference in elevation, which reduces the need for earth-moving equipment. As drilling moves closer to farms and acreages, minimal environmental disturbance is crucial to the CBM industry. The rig won a 2005 Alberta government award for innovations in workplace health and safety as the design eliminates many of the tasks where injuries occur on conventional rigs. On conventional rigs, drill-strings are suspended from a travelling block which is suspended from the crown of a large, heavy derrick. With the ADR, hydraulic cylinders bear the weight of the drill string, and the derrick serves mainly to guide the top drive. When drilling only with jointed pipe, the coiled-tubing reel is a separate load so that drilling crews don't have to transport it around on programs requiring only jointed pipe. If coil is needed, the reel can be trucked to the site and plugged in to the rest of the rig. Tubing is expected to last 3 times as long as on a regular coiled-tubing rig, as the reel is positioned directly over the rotary table. The rigs have been used for various drilling projects and have performed satisfactorily with high penetration rates due to their large mud pumps. It was concluded that the ADR-1000-CT rig's hydraulic self-levelling capability and agility are helpful features when drilling in a minimal disturbance environment. 3 figs

  12. A study of natural circulation cooling using a flow visualization rig

    International Nuclear Information System (INIS)

    Bowman, W.C.; Ferch, R.L.; Omar, A.M.

    1985-01-01

    A flow visualization rig has been built at Monserco Limited to provide visual insight into the thermalhydraulic phenomena which occur during single phase and two phase thermosyphoning in a figure-of-eight heat transport loop. Tests performed with the rig have provided design information for the scaling and instrumentation of a high pressure rig being investigated for simulating CANDU reactor conditions during natural circulation cooling. A videotape was produced, for viewing at this presentation, to show important thermalhydraulic features of the thermosyphoning process. The rig is a standard figure-of-eight loop with two steam generators and three heated channels per pass. An elevated surge tank open to atmosphere was used for pressure control. Two variable speed pumps provided forced circulation for warming up the rig, and for establishing the desired initial conditions for testing. Test rig power could be varied between 0 and 15 kW

  13. LWR primary coolant pipe rupture test rig

    International Nuclear Information System (INIS)

    Yoshitoshi, Shyoji

    1978-01-01

    The rupture test rig for primary coolant pipes is constructed in the Japan Atomic Energy Research Institute to verify the reliability of the primary coolant pipes for both PWRs and BWRs. The planned test items consisted of reaction force test, restraint test, whip test, jet test and continuous release test. A pressure vessel of about 4 m 3 volume, a circulating pump, a pressurizer, a heater, an air cooler and the related instrumentation and control system are included in this test rig. The coolant test condition is 160 kg/cm 2 g, 325 deg C for PWR test, and 70 kg/cm 2 g, saturated water and steam for BWR test, 100 ton of test load for the ruptured pipe bore of 8B Schedule 160, and 20 lit/min. discharge during 20 h for continuous release of coolant. The maximum pit internal pressure was estimated for various pipe diameters and time under the PWR and BWR conditions. The spark rupturing device was adopted for the rupture mechanics in this test rig. The computer PANAFACOM U-300 is used for the data processing. This test rig is expected to operate in 1978 effectively for the improvement of reliability of LWR primary coolant pipes. (Nakai, Y.)

  14. Argentina's YPF outlines plan for sale of rigs

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that state owned Yacimientos Petroliferos Fiscales (YPF) has unveiled the schedule it plans to follow to privatize oil and gas contract drilling in Argentine. YPF proposes to exit the drilling business by selling state owned drilling rigs, drill pipe, and accessories in a series of auctions beginning next month and lasting through first quarter 1993. YPF intends to open bids Dec. 16 for a completion unit and 30 drilling rigs, several working under contract. Bids will be opened during first quarter 1993 for new and used YPF drill pipe and collars, spare equipment and accessories, and an inventory of fishing tools said to be one of the largest in South America. Winners are to be notified immediately after each auction. YPF plans to hand over by Feb. 1, 1993, the rigs sold in December. Companies buying YPF drilling assets in first quarter 1993, the rigs sold in December. Companies buying YPF drilling assets in first quarter 1993 are to assume ownership by Mar. 24, 1993

  15. Index method for analyzing cost effectiveness of drilling rigs

    Energy Technology Data Exchange (ETDEWEB)

    Batura, N P; Bocharov, V V

    1978-01-01

    The method for a complete analysis of the factors determining cost effectiveness of a drilling rig fleet is examined. The system of calculating production indexes from statistical reports is relatively simple and is not difficult to use for production organizations. The analytical results may be used to develop actual measures used to increase cost effectiveness of drilling operations.

  16. Essays on bid rigging

    NARCIS (Netherlands)

    Seres, Gyula

    2016-01-01

    Manipulating prices in auctions raises antitrust concerns. Collusion lowers the revenue of the auctioneer and creates information rents. Bid rigging is a prevalent phenomenon and the affected market is enormous. Public procurement amounts to between 10 and 25 percent of national GDP in

  17. Validation of RELAP5 model of experimental test rig simulating the natural convection in MTR research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Khedr, A.; Abdel-Latif, Salwa H. [Nuclear and Radiological Regulatory Authority, Cairo (Egypt); Abdel-Hadi, Eed A. [Benha Univ., Cairo (Egypt). Shobra Faculty of Engineering; D' Auria, F. [Pisa Univ. (Italy)

    2016-03-15

    In an attempt to understand the built-up of natural circulation in MTR pool type upward flow research reactors after loss of power, an experimental test rig was built to simulate the loop of natural circulation in MTR reactors. The test rig consisting of two vertically oriented branches, in one of them the core is simulated by two rectangular, electrically heated, parallel channels. The other branch simulates the part of the return pipe that participates in the development of core natural circulation. In the first phase of the work, many experimental runs at different conditions of channel's power and branch's initial temperatures are performed. The channel's coolant and surface temperatures were measured. The measurements and their interpretation were published by the first three authors. In the present work the thermal hydraulic behavior of the test rig is complemented by theoretical analysis using RELAP5 Mod 3.3 system code. The analysis consisting of two parts; in the first part RELAP5 model is validated against the measured values and in the second part some of the other not measured hydraulic parameters are predicted and analyzed. The test rig is typically nodalized and an input dick is prepared. In spite of the low pressure of the test rig, the results show that RELAP5 qualitatively predicts the thermal hydraulic behaviour and the accompanied phenomenon of flow inversion of such facilities. Quantitatively, there is a difference between the predicted and measured values especially the channel's surface temperature. This difference may be return to the uncertainties in initial conditions of experimental runs, the position of the thermocouples which buried inside the heat structure, and the heat transfer package in RELAP5.

  18. RIG-I self-oligomerization is either dispensable or very transient for signal transduction.

    Directory of Open Access Journals (Sweden)

    Jade Louber

    Full Text Available Effective host defence against viruses depends on the rapid triggering of innate immunity through the induction of a type I interferon (IFN response. To this end, microbe-associated molecular patterns are detected by dedicated receptors. Among them, the RIG-I-like receptors RIG-I and MDA5 activate IFN gene expression upon sensing viral RNA in the cytoplasm. While MDA5 forms long filaments in vitro upon activation, RIG-I is believed to oligomerize after RNA binding in order to transduce a signal. Here, we show that in vitro binding of synthetic RNA mimicking that of Mononegavirales (Ebola, rabies and measles viruses leader sequences to purified RIG-I does not induce RIG-I oligomerization. Furthermore, in cells devoid of endogenous functional RIG-I-like receptors, after activation of exogenous Flag-RIG-I by a 62-mer-5'ppp-dsRNA or by polyinosinic:polycytidylic acid, a dsRNA analogue, or by measles virus infection, anti-Flag immunoprecipitation and specific elution with Flag peptide indicated a monomeric form of RIG-I. Accordingly, when using the Gaussia Luciferase-Based Protein Complementation Assay (PCA, a more sensitive in cellula assay, no RIG-I oligomerization could be detected upon RNA stimulation. Altogether our data indicate that the need for self-oligomerization of RIG-I for signal transduction is either dispensable or very transient.

  19. The development of fuel pins and material specimens mixed loading irradiation test rig in the experimental fast reactor Joyo. The development of the fuel-material hybrid rig

    International Nuclear Information System (INIS)

    Oyamatsu, Yasuko; Someya, Hiroyuki

    2013-02-01

    In the experimental fast reactor Joyo, there were many tests using the irradiation rigs that it was possible to be set irradiation conditions for each compartment independently. In case of no alternative fuel element to irradiate after unloading the irradiated compartments, the irradiation test was restarted with the dummy compartment which the fuel elements was not mounted. If the material specimens are mounted in this space, it is possible to use the irradiation space effectively. For these reasons, the irradiation rig (hybrid rig) is developed that is consolidated with material specimens compartment and fuel elements compartment. Fuel elements and material specimens differ greatly with heat generation, so that the most important issue in developing of hybrid rig is being able to distribute appropriately the coolant flow which satisfies irradiation conditions. The following is described by this report. (1) It was confirmed that the flow distribution of loading the same irradiation rig with the compartment from which a flow demand differs could be satisfied. (2) It was confirmed that temperature setting range of hybrid rig could be equivalent to that of irradiation condition. (3) By standardizing the coolant entrance structure of the compartment lower part, the prospect which can perform easily recombination of the compartment from which a type differs between irradiation rigs was acquired. (author)

  20. Lapland longspur mortality at an oil well drilling rig site, Laramie County, Wyoming

    Science.gov (United States)

    Ramirez, Pedro; Dickerson, Kimberly K.; Lindstrom, Jim; Meteyer, Carol U.; Darrah, Scott

    2015-01-01

    Two hundred fifty-one Lapland longspur (Calcarius lapponicus) carcasses were recovered around an oil well drilling rig in Laramie County, Wyoming, USA, on December 13–14, 2010, apparent victims of a winter storm and “light entrapment” from the lights on the drilling rig during foggy conditions. We found Lapland longspur carcasses distributed around the drilling rig from 33 m to 171 m. Investigators did not find evidence of bird carcasses on the drilling rig deck or equipment immediately adjacent to the drilling rig. We ruled out chemical toxins and disease as a cause of mortality. Weather conditions, the circular depositional pattern of carcasses around the drilling rig, and bird necropsy results led investigators to conclude that the Lapland longspur mortality was the result of the migrating birds entering the area illuminated by the drilling rig lights in freezing fog and the birds repeatedly circling the drilling rig until they fell to the ground in exhaustion and dying from subsequent trauma. Further research is needed to understand how to most effectively adjust lighting of onshore drilling rigs to reduce the potential for avian light entrapment. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  1. Duck RIG-I CARD Domain Induces the Chicken IFN-β by Activating NF-κB

    Directory of Open Access Journals (Sweden)

    Yang Chen

    2015-01-01

    Full Text Available Retinoic acid-inducible gene I- (RIG-I- like receptors (RLRs have recently been identified as cytoplasmic sensors for viral RNA. RIG-I, a member of RLRs family, plays an important role in innate immunity. Although previous investigations have proved that RIG-I is absent in chickens, it remains largely unknown whether the chicken can respond to RIG-I ligand. In this study, the eukaryotic expression vectors encoding duRIG-I full length (duck RIG-I, containing all domains, duRIG-I N-terminal (containing the two caspase activation and recruitment domain, CARDs, and duRIG-I C-terminal (containing helicase and regulatory domains labeled with 6*His tags were constructed successfully and detected by western blotting. Luciferase reporter assay and enzyme-linked immunosorbent assay (ELISA detected the duRIG-I significantly activated NF-κB and induced the expression of IFN-β when polyinosinic-polycytidylic acid (poly[I:C], synthetic double-stranded RNA challenges chicken embryonic fibroblasts cells (DF1 cells, while the duRIG-I was inactive in the absence of poly[I:C]. Further analysis revealed that the CARDs (duRIG-I-N induced IFN-β production regardless of the presence of poly[I:C], while the CARD-lacking duRIG-I (duRIG-I-C was not capable of activating downstream signals. These results indicate that duRIG-I CARD domain plays an important role in the induction of IFN-β and provide a basis for further studying the function of RIG-I in avian innate immunity.

  2. Professional development of new rig supervisors a must

    International Nuclear Information System (INIS)

    Nordt, D.P.; Stone, M.S.

    1992-01-01

    This paper reports that because the number of drilling personnel has dropped dramatically over the last decade, many operators now face a shortage of competent rig supervisors. To be effective, the rig supervisor must develop a knowledge of drilling operations, apply optimization techniques to improve drilling performance, demand safe work practices, and protect the environment. Petroleum engineering degree programs and industry training programs can teach the rig supervisor specific technical and management skills; however, traditionally, the supervisor trainee shadows an experienced company man to learn how to direct a drilling operation. The success of this method depends not only on the skills and learning capabilities of the trainee but also on the trainer's time, motivation, knowledge, and ability to teach the skills necessary to direct drilling activities

  3. Seasonal variation of the global mixed layer depth: comparison between Argo data and FIO-ESM

    Science.gov (United States)

    Zhang, Yutong; Xu, Haiming; Qiao, Fangli; Dong, Changming

    2018-03-01

    The present study evaluates a simulation of the global ocean mixed layer depth (MLD) using the First Institute of Oceanography-Earth System Model (FIOESM). The seasonal variation of the global MLD from the FIO-ESM simulation is compared to Argo observational data. The Argo data show that the global ocean MLD has a strong seasonal variation with a deep MLD in winter and a shallow MLD in summer, while the spring and fall seasons act as transitional periods. Overall, the FIO-ESM simulation accurately captures the seasonal variation in MLD in most areas. It exhibits a better performance during summer and fall than during winter and spring. The simulated MLD in the Southern Hemisphere is much closer to observations than that in the Northern Hemisphere. In general, the simulated MLD over the South Atlantic Ocean matches the observation best among the six areas. Additionally, the model slightly underestimates the MLD in parts of the North Atlantic Ocean, and slightly overestimates the MLD over the other ocean basins.

  4. Drilling rig

    Energy Technology Data Exchange (ETDEWEB)

    Galiopa, A A; Yegorov, E K

    1981-01-04

    A drilling rig is proposed which contains a tower, lifter in the form of n infinite chain, and mobile rotator with holding device connected to the chain, and pipe holder. In order to accelerate the auxiliary operations to move the drilling string and unloaded rotator, the rotator is equipped with a clamp with means for transverse connection of it to both branches of the chain, while the pipe holders equipped with a clamp with means of connecting it to one of the branches of the chain.

  5. 21 CFR 118.4 - Salmonella Enteritidis (SE) prevention measures.

    Science.gov (United States)

    2010-04-01

    ... specified in § 118.6, within 2 weeks of the start of egg laying. (3) Cleaning and disinfection. If the... house to remove dust, feathers, and old feed; and (iii) Following cleaning, disinfection of the positive... harborage for pests. (d) Cleaning and disinfection. You must clean and disinfect the poultry house according...

  6. The Thermal-hydraulic Performance Test Report for the Non-instrumented Irradiation Test Rig of Annular Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dae Ho; Lee, Kang Hee; Shin, Chang Hwan

    2008-09-15

    This report presents the results of pressure drop test, vibration test and endurance test for the non-instrumented rig using the irradiation test in HANARO of the double cooled annular fuel which were designed and fabricated by KAERI. From the out-pile thermal hydraulic tests, corresponding to the pressure drop of 200 kPa is measured to be about 9.72 kg/sec. Vibration frequency for the non-instrumented rig ranges from 5.0 to 10.7 kg/s. RMS(Root Mean Square) displacement for non-instrumented rig is less than 11.73 m, and the maximum displacement is less than 54.87m. The flow rate for endurance test were 10.5 kg/s, which was 110% of 9.72 kg/s. And the endurance test was carried out for 3 days. The test results found not to the wear and satisfied to the limits of pressure drop, flow rate, vibration and wear in the non-instrumented rig. This test was performed at the FIVPET facility.

  7. A constructive presentation of rigged Hilbert spaces

    International Nuclear Information System (INIS)

    Celeghini, Enrico

    2015-01-01

    We construct a rigged Hilbert space for the square integrable functions on the line L2(R) adding to the generators of the Weyl-Heisenberg algebra a new discrete operator, related to the degree of the Hermite polynomials. All together, continuous and discrete operators, constitute the generators of the projective algebra io(2). L 2 (R) and the vector space of the line R are shown to be isomorphic representations of such an algebra and, as both these representations are irreducible, all operators defined on the rigged Hilbert spaces L 2 (R) or R are shown to belong to the universal enveloping algebra of io(2). The procedure can be extended to orthogonal and pseudo-orthogonal spaces of arbitrary dimension by tensorialization.Circumventing all formal problems the paper proposes a kind of toy model, well defined from a mathematical point of view, of rigged Hilbert spaces where, in contrast with the Hilbert spaces, operators with different cardinality are allowed. (paper)

  8. Plans d'expérience constructions et analyses statistiques

    CERN Document Server

    Tinsson, Walter

    2010-01-01

    Il est souvent n cessaire de r aliser des exp riences afin de mod liser le comportement d un ph nom ne complexe. La m thode des plans d exp rience a pour objectif d obtenir un maximum d information sur le ph nom ne tudi en un minimum d exp riences. Ceci est primordial si l objectif est un gain de temps ou de qualit . Cet ouvrage d taille les fondements th oriques de la m thode math matique des plans d exp rience. Ceci est abord tout au long des quatre parties suivantes. Pr sentation g n rale de la m thode et des outils math matiques. Plans d exp rience pour facteurs quantitatifs: mod le d ordr

  9. The method of rigged spaces in singular perturbation theory of self-adjoint operators

    CERN Document Server

    Koshmanenko, Volodymyr; Koshmanenko, Nataliia

    2016-01-01

    This monograph presents the newly developed method of rigged Hilbert spaces as a modern approach in singular perturbation theory. A key notion of this approach is the Lax-Berezansky triple of Hilbert spaces embedded one into another, which specifies the well-known Gelfand topological triple. All kinds of singular interactions described by potentials supported on small sets (like the Dirac δ-potentials, fractals, singular measures, high degree super-singular expressions) admit a rigorous treatment only in terms of the equipped spaces and their scales. The main idea of the method is to use singular perturbations to change inner products in the starting rigged space, and the construction of the perturbed operator by the Berezansky canonical isomorphism (which connects the positive and negative spaces from a new rigged triplet). The approach combines three powerful tools of functional analysis based on the Birman-Krein-Vishik theory of self-adjoint extensions of symmetric operators, the theory of singular quadra...

  10. Operating experience of a sodium rig following the ingress of oil

    Energy Technology Data Exchange (ETDEWEB)

    Bell, A C; Mehew, R D; Robertson, C M [UKAEA, Dounreay, Thurso, Caithness, Scotland (United Kingdom)

    1980-05-01

    The experience of operating the Small Water Leak Rig at Dounreay in the two years following the ingress into the sodium of silicone oil from the pump is reported. The carbon penetration into the rig pipework has been monitored and has been found to agree with a diffusion model. The predictions based on this model have enabled an operating strategy to be determined to allow continued operation of the rig. (author)

  11. Operating experience of a sodium rig following the ingress of oil

    International Nuclear Information System (INIS)

    Bell, A.C.; Mehew, R.D.; Robertson, C.M.

    1980-01-01

    The experience of operating the Small Water Leak Rig at Dounreay in the two years following the ingress into the sodium of silicone oil from the pump is reported. The carbon penetration into the rig pipework has been monitored and has been found to agree with a diffusion model. The predictions based on this model have enabled an operating strategy to be determined to allow continued operation of the rig. (author)

  12. CONCENTRIC TUBE-FOULING RIG FOR INVESTIGATION OF FOULING DEPOSIT FORMATION FROM PASTEURISER OF VISCOUS FOOD LIQUID

    Directory of Open Access Journals (Sweden)

    N. I. KHALID

    2013-02-01

    Full Text Available This paper reports the work on developing concentric tube-fouling rig, a new fouling deposit monitoring device. This device can detect and quantify the level of fouling deposit formation. It can also functioning as sampler for fouling deposit study, which can be attached at any food processing equipment. The design is initiated with conceptual design. The rig is designed with inner diameter of 7 cm and with tube length of 37 cm. A spiral insert with 34.5 cm length and with 5.4 cm diameter is fitted inside the tube to ensure the fluid flows around the tube. In this work, the rig is attached to the lab-scale concentric tube-pasteurizer to test its effectiveness and to collect a fouling sample after pasteurization of pink guava puree. Temperature changes are recorded during the pasteurization and the data is used to plot the heat transfer profile. Thickness of the fouling deposit is also measured. The trends for thickness, heat resistance profile and heat transfer profile for concentric tube-fouling rig matched the trends obtained from lab-scale concentric tube-pasteurizer very well. The findings from this work have shown a good potential of this rig however there is a limitation with spiral insert, which is discussed in this paper.

  13. Negative Role of RIG-I Serine 8 Phosphorylation in the Regulatin of Interferon-beta Production

    Energy Technology Data Exchange (ETDEWEB)

    E Nistal-Villan; M Gack; G Martinez-Delgado; N Maharaj; K Inn; H Yang; R Wang; A Aggarwal; J Jung; A Garcia-Sastre

    2011-12-31

    RIG-I (retinoic acid-inducible gene I) and TRIM25 (tripartite motif protein 25) have emerged as key regulatory factors to induce interferon (IFN)-mediated innate immune responses to limit viral replication. Upon recognition of viral RNA, TRIM25 E3 ligase binds the first caspase recruitment domain (CARD) of RIG-I and subsequently induces lysine 172 ubiquitination of the second CARD of RIG-I, which is essential for the interaction with downstream MAVS/IPS-1/CARDIF/VISA and, thereby, IFN-beta mRNA production. Although ubiquitination has emerged as a major factor involved in RIG-I activation, the potential contribution of other post-translational modifications, such as phosphorylation, to the regulation of RIG-I activity has not been addressed. Here, we report the identification of serine 8 phosphorylation at the first CARD of RIG-I as a negative regulatory mechanism of RIG-I-mediated IFN-beta production. Immunoblot analysis with a phosphospecific antibody showed that RIG-I serine 8 phosphorylation steady-state levels were decreased upon stimulation of cells with IFN-beta or virus infection. Substitution of serine 8 in the CARD RIG-I functional domain with phosphomimetic aspartate or glutamate results in decreased TRIM25 binding, RIG-I ubiquitination, MAVS binding, and downstream signaling. Finally, sequence comparison reveals that only primate species carry serine 8, whereas other animal species carry an asparagine, indicating that serine 8 phosphorylation may represent a primate-specific regulation of RIG-I activation. Collectively, these data suggest that the phosphorylation of RIG-I serine 8 operates as a negative switch of RIG-I activation by suppressing TRIM25 interaction, further underscoring the importance of RIG-I and TRIM25 connection in type I IFN signal transduction.

  14. Advantages and limitations of remotely operated sea floor drill rigs

    Science.gov (United States)

    Freudenthal, T.; Smith, D. J.; Wefer, G.

    2009-04-01

    A variety of research targets in marine sciences including the investigation of gas hydrates, slope stability, alteration of oceanic crust, ore formation and palaeoclimate can be addressed by shallow drilling. However, drill ships are mostly used for deep drillings, both because the effort of building up a drill string from a drill ship to the deep sea floor is tremendous and control on drill bit pressure from a movable platform and a vibrating drill string is poor especially in the upper hundred meters. During the last decade a variety of remotely operated drill rigs have been developed, that are deployed on the sea bed and operated from standard research vessels. These developments include the BMS (Bentic Multicoring System, developed by Williamson and Associates, operated by the Japanese Mining Agency), the PROD (Portable Remotely Operated Drill, developed and operated by Benthic Geotech), the Rockdrill 2 (developed and operated by the British geological Survey) and the MeBo (German abbreviation for sea floor drill rig, developed and operated by Marum, University of Bremen). These drill rigs reach drilling depths between 15 and 100 m. For shallow drillings remotely operated drill rigs are a cost effective alternative to the services of drill ships and have the major advantage that the drilling operations are performed from a stable platform independent of any ship movements due to waves, wind or currents. Sea floor drill rigs can be deployed both in shallow waters and the deep sea. A careful site survey is required before deploying the sea floor drill rig. Slope gradient, small scale topography and soil strength are important factors when planning the deployment. The choice of drill bits and core catcher depend on the expected geology. The required drill tools are stored on one or two magazines on the drill rig. The MeBo is the only remotely operated drill rig world wide that can use wire line coring technique. This method is much faster than conventional

  15. Use of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality.

    Science.gov (United States)

    Alonso-Caneiro, David; Sampson, Danuta M; Chew, Avenell L; Collins, Michael J; Chen, Fred K

    2018-02-01

    Adaptive optics flood illumination ophthalmoscopy (AO-FIO) allows imaging of the cone photoreceptor in the living human retina. However, clinical interpretation of the AO-FIO image remains challenging due to suboptimal quality arising from residual uncorrected wavefront aberrations and rapid eye motion. An objective method of assessing image quality is necessary to determine whether an AO-FIO image is suitable for grading and diagnostic purpose. In this work, we explore the use of focus measure operators as a surrogate measure of AO-FIO image quality. A set of operators are tested on data sets acquired at different focal depths and different retinal locations from healthy volunteers. Our results demonstrate differences in focus measure operator performance in quantifying AO-FIO image quality. Further, we discuss the potential application of the selected focus operators in (i) selection of the best quality AO-FIO image from a series of images collected at the same retinal location and (ii) assessment of longitudinal changes in the diseased retina. Focus function could be incorporated into real-time AO-FIO image processing and provide an initial automated quality assessment during image acquisition or reading center grading.

  16. Computers make rig life extension an option

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The worldwide semisubmersible drilling rig fleet is approaching retirement. But replacement is not an attractive option even though dayrates are reaching record highs. In 1991, Schlumberger Sedco Forex managers decided that an alternative might exist if regulators and insurers could be convinced to extend rig life expectancy through restoration. Sedco Forex chose their No. 704 semisubmersible, an 18-year North Sea veteran, to test their process. The first step was to determine what required restoration, meaning fatigue life analysis of each weld on the huge vessel. If inspected, the task would be unacceptably time-consuming and of questionable accuracy. Instead a suite of computer programs modeled the stress seen by each weld, statistically estimated the sea states seen by the rig throughout its North Sea service and calibrated a beam-element model on which to run their computer simulations. The elastic stiffness of the structure and detailed stress analysis of each weld was performed with ANSYS, a commercially available finite-element analysis program. The use of computer codes to evaluate service life extension is described.

  17. Um novo fio de aço inoxidável para aplicações ortodônticas A new stainless steel wire for orthodontic purposes

    Directory of Open Access Journals (Sweden)

    André Itman Filho

    2011-08-01

    Full Text Available OBJETIVO: desenvolver uma metodologia para fabricação de fios ortodônticos de aço inoxidável austeno-ferrítico SEW 410 Nr. 14517 por meio dos processos convencionais de laminação e trefilação. MÉTODOS: o aço austeno-ferrítico foi elaborado em um forno elétrico de indução. A qualidade dos fios foi avaliada por ensaios de tração e medidas de microdureza. A ductilidade e a manuseabilidade foram analisadas por meio da confecção de componentes ortodônticos. RESULTADOS E CONCLUSÕES: os valores encontrados mostraram que os fios de aço inoxidável austeno-ferrítico atenderam às normas BS 3507:1976 e ISO 5832-1, e apresentaram ótima ductilidade para confecção de componentes ortodônticos com dobras complexas.OBJECTIVE: To develop a method to manufacture austenitic-ferritic stainless steel orthodontic wires (SEW 410 Nr. 14517 using conventional rolling and wiredrawing processes. METHODS: Austenitic-ferritic steel was produced in an induction furnace. Traction trials and microhardness measurements were used to evaluate wire quality. Orthodontic parts were fabricated to assess ductility and malleability. RESULTS AND CONCLUSIONS: Austenitic-ferritic stainless steel wires meet the BS 3507:1976 and ISO 5832-1 norms and have excellent ductility for the fabrication of orthodontic parts with complex folds.

  18. IT that works on the rig floor : computers on drilling rigs need to be certified and built with features that can handle the environment

    Energy Technology Data Exchange (ETDEWEB)

    Balsaver, N.

    2010-07-15

    This article discussed the design challenges faced in developing hazardous-location computers for rig-floor use and other recently introduced products from Laversab. Rig-floor computers must not only be certified as Zone-1 or Zone-2 compliant but must also have features that make them work dependably in an extreme environment, including a wide operating temperature range, an ability to withstand severe vibration, immunity to salt fog, a viewable display in bright daylight, networking capability, USB and serial interfaces, and touch screens. Size and weight has been a major obstacle, but recent innovations have made Zone-1 computers intrinsically safe (IS), making them much smaller and lighter. Wireless networking eliminates the need for installing copper and fibre-optic cabling, but the wireless interface must be strong enough to overcome the many obstructions that are typically present on oil rigs. The computer models described, including a Driller's Display designed to be IS for Zone-1 applications and a Directional MWD Surface System designed for Zone-2 applications, provide solutions to the challenges of a working rig-floor environment. 3 figs.

  19. RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

    Science.gov (United States)

    Zhu, Huiyuan; Lou, Fangzhou; Yin, Qianqian; Gao, Yuanyuan; Sun, Yang; Bai, Jing; Xu, Zhenyao; Liu, Zhaoyuan; Cai, Wei; Ke, Fang; Zhang, Lingyun; Zhou, Hong; Wang, Hong; Wang, Gang; Chen, Xiang; Zhang, Hongxin; Wang, Zhugang; Ginhoux, Florent; Lu, Chuanjian; Su, Bing; Wang, Honglin

    2017-05-01

    Retinoic acid inducible-gene I (RIG-I) functions as one of the major sensors of RNA viruses. DDX58 , which encodes the RIG-I protein, has been newly identified as a susceptibility gene in psoriasis. Here, we show that the activation of RIG-I by 5'ppp-dsRNA, its synthetic ligand, directly causes the production of IL-23 and triggers psoriasis-like skin disease in mice. Repeated injections of IL-23 to the ears failed to induce IL-23 production and a full psoriasis-like skin phenotype, in either germ-free or RIG-I-deficient mice. RIG-I is also critical for a full development of skin inflammation in imiquimod (IMQ)-induced psoriasis-like mouse model. Furthermore, RIG-I-mediated endogenous IL-23 production was mainly confined to the CD11c + dendritic cells (DCs) via nuclear factor-kappa B (NF-κB) signaling, and stimulated RIG-I expression in an auto-regulatory feedback loop. Thus, our data suggest that the dysregulation in the antiviral immune responses of hosts through the innate pattern recognition receptors may trigger the skin inflammatory conditions in the pathophysiology of psoriasis. © 2017 The Authors. Published under the terms of the CC BY 4.0 license.

  20. A Universal Rig for Supporting Large Hammer Drills: Reduced Injury Risk and Improved Productivity.

    Science.gov (United States)

    Rempel, David; Barr, Alan

    2015-10-01

    Drilling holes into concrete with heavy hammer and rock drills is one of the most physically demanding tasks performed in commercial construction and poses risks for musculoskeletal disorders, noise induced hearing loss, hand arm vibration syndrome and silicosis. The aim of this study was to (1) use a participatory process to develop a rig to support pneumatic rock drills or large electric hammer drills in order to reduce the health risks and (2) evaluate the usability of the rig. Seven prototype rigs for supporting large hammer drills were developed and modified with feedback from commercial contractors and construction workers. The final design was evaluated by laborers and electricians (N=29) who performed their usual concrete drilling with the usual method and the new rig. Subjective regional fatigue was significantly less in the neck, shoulders, hands and arms, and lower back) when using the universal rig compared to the usual manual method. Usability ratings for the rig were significantly better than the usual method on stability, control, drilling, accuracy, and vibration. Drilling time was reduced by approximately 50% with the rig. Commercial construction contractors, laborers and electricians who use large hammer drills for drilling many holes should consider using such a rig to prevent musculoskeletal disorders, fatigue, and silicosis.

  1. Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein

    International Nuclear Information System (INIS)

    Lee, Na-Rae; Shin, Han-Bo; Kim, Hye-In; Choi, Myung-Soo; Inn, Kyung-Soo

    2013-01-01

    Highlights: •TRK-fused gene product (TFG) interacts with TRIM25 upon viral infection. •TFG negatively regulates RIG-I mediated antiviral signaling. •TFG depletion leads to enhanced viral replication. •TFG act downstream of MAVS. -- Abstract: RIG-I (retinoic acid inducible gene I)-mediated antiviral signaling serves as the first line of defense against viral infection. Upon detection of viral RNA, RIG-I undergoes TRIM25 (tripartite motif protein 25)-mediated K63-linked ubiquitination, leading to type I interferon (IFN) production. In this study, we demonstrate that TRK-fused gene (TFG) protein, previously identified as a TRIM25-interacting protein, binds TRIM25 upon virus infection and negatively regulates RIG-I-mediated type-I IFN signaling. RIG-I-mediated IFN production and nuclear factor (NF)-κB signaling pathways were upregulated by the suppression of TFG expression. Furthermore, vesicular stomatitis virus (VSV) replication was significantly inhibited by small inhibitory hairpin RNA (shRNA)-mediated knockdown of TFG, supporting the suppressive role of TFG in RIG-I-mediated antiviral signaling. Interestingly, suppression of TFG expression increased not only RIG-I-mediated signaling but also MAVS (mitochondrial antiviral signaling protein)-induced signaling, suggesting that TFG plays a pivotal role in negative regulation of RNA-sensing, RIG-I-like receptor (RLR) family signaling pathways

  2. 7 CFR 1150.118 - Marketing.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Marketing. 1150.118 Section 1150.118 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Definitions § 1150.118 Marketing. Marketing means the sale or other disposition in commerce of...

  3. 7 CFR 1260.118 - Cattle.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Cattle. 1260.118 Section 1260.118 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Promotion and Research Order Definitions § 1260.118 Cattle. Cattle means live domesticated bovine animals...

  4. Endurance test for IR rig for RI production assembly (test procedure)

    International Nuclear Information System (INIS)

    Chung, Heung June; Ryu, Jeong Soo

    2000-08-01

    This test procedure details the test loop, test method, and test procedure for pressure drop, vibration and endurance test of IR Rig for RI production. From the pressure drop test, the hydraulic design requirements of the capsule are verified. HANARO limit condition is checked and the compatibility with HANARO core is verified. From flow induced vibration test vibration frequency and displacement are investigated. The wear of IR Rig is investigated through endurance test, and these data are used to evaluate the expected wear at maximum resident time of the IR Rig for RI production

  5. Test Rig Design and Presentation for a Hydraulic Yaw System

    DEFF Research Database (Denmark)

    Stubkier, Søren; Pedersen, Henrik C.; Andersen, Torben Ole

    2013-01-01

    The design and development of a hydraulic yaw system for multi MWturbines is presented and the concept explained. As part of the development of the new concept a full scale test rig for a 5 MW wind turbine has been designed and constructed. The test rig is presented along with its unique design...... features. The design process is outlined to give insight in the design criteria driving the design. Loads and yaw demands are based on the IEC 61400-1 standard for wind turbine design, and the loads for this examination are extrapolated from the FAST aero elastic design software. The concepts are based...... on a 5 MW offshore turbine. After the system presentation, measurement results are presented to verify the behavior of the system. The loads to the system are applied by torque controlled electrical servo drives, which can add a load of up to 3 MNm to the system. This gives an exact picture of the system...

  6. DMPD: MDA5/RIG-I and virus recognition. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18272355 MDA5/RIG-I and virus recognition. Takeuchi O, Akira S. Curr Opin Immunol. ...2008 Feb;20(1):17-22. Epub 2008 Feb 12. (.png) (.svg) (.html) (.csml) Show MDA5/RIG-I and virus recognition.... PubmedID 18272355 Title MDA5/RIG-I and virus recognition. Authors Takeuchi O, Akira S. Publication Curr Opi

  7. 7 CFR 900.118 - Costs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Costs. 900.118 Section 900.118 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Meetings To Arbitrate and Mediate Disputes Relating to Sales of Milk or Its Products § 900.118 Costs. The...

  8. Design and commission of an experimental test rig to apply a full-scale pressure load on composite sandwich panels representative of an aircraft secondary structure

    International Nuclear Information System (INIS)

    Crump, D A; Dulieu-Barton, J M; Savage, J

    2010-01-01

    This paper describes the design of a test rig, which is used to apply a representative pressure load to a full-scale composite sandwich secondary aircraft structure. A generic panel was designed with features to represent those in the composite sandwich secondary aircraft structure. To provide full-field strain data from the panels, the test rig was designed for use with optical measurement techniques such as thermoelastic stress analysis (TSA) and digital image correlation (DIC). TSA requires a cyclic load to be applied to a structure for the measurement of the strain state; therefore, the test rig has been designed to be mounted on a standard servo-hydraulic test machine. As both TSA and DIC require an uninterrupted view of the surface of the test panel, an important consideration in the design is facilitating the optical access for the two techniques. To aid the test rig design a finite element (FE) model was produced. The model provides information on the deflections that must be accommodated by the test rig, and ensures that the stress and strain levels developed in the panel when loaded in the test rig would be sufficient for measurement using TSA and DIC. Finally, initial tests using the test rig have shown it to be capable of achieving the required pressure and maintaining a cyclic load. It was also demonstrated that both TSA and DIC data can be collected from the panels under load, which are used to validate the stress and deflection derived from the FE model

  9. The economics and related factors involved in the replacement of land drilling rigs

    International Nuclear Information System (INIS)

    Holm, D.W.

    1992-01-01

    The principal purpose of this paper is to evaluate the construction cost of a medium depth land rig made from all NEW components and the resulting effect on drilling contractor economics. This evaluation will include an inventory of the proposed NEW rig, with a comparison of the costs of a similar rig built in 1981-1982, and a similar rig built from existing UNUSED equipment in manufacturer's current inventory. The paper discusses the problems encountered in obtaining quotations for NEW equipment from manufacturers, the current attitudes of equipment manufacturers, the potential for problems from the use of existing UNUSED equipment in manufacturers inventory, and finally the possible effect on the day rates needed to justify the construction of NEW land rigs. Probable reasons for the attitudes of the manufacturing industry and alternatives for the drilling contractor will be reviewed

  10. Development Of Test Rig System For Calibration Of Temperature Sensing Fabric

    Directory of Open Access Journals (Sweden)

    Husain Muhammad Dawood

    2017-09-01

    Full Text Available A test rig is described, for the measurement of temperature and resistance parameters of a Temperature Sensing Fabric (TSF for calibration purpose. The equipment incorporated a temperature-controlled hotplate, two copper plates, eight thermocouples, a temperature data-logger and a four-wire high-resolution resistance measuring multimeter. The copper plates were positioned above and below the TSF and in physical contact with its surfaces, so that a uniform thermal environment might be provided. The temperature of TSF was estimated by the measurement of temperature profiles of the two copper plates. Temperature-resistance graphs were created for all the tests, which were carried out over the range of 20 to 50°C, and they showed that the temperature and resistance values were not only repeatable but also reproducible, with only minor variations. The comparative analysis between the temperature-resistance test data and the temperature-resistance reference profile showed that the error in estimation of temperature of the sensing element was less than ±0.2°C. It was also found that the rig not only provided a stable and homogenous thermal environment but also offered the capability of accurately measuring the temperature and resistance parameters. The Temperature Sensing Fabric is suitable for integration into garments for continuous measurement of human body temperature in clinical and non-clinical settings.

  11. A power recirculating test rig for ball screw endurance tests

    Directory of Open Access Journals (Sweden)

    Giberti Hermes

    2016-01-01

    Full Text Available A conceptual design of an innovative test rig for endurance tests of ball screws is presented in this paper. The test rig layout is based on the power recirculating principle and it also allows to overtake the main critical issues of the ball screw endurance tests. Among these there are the high power required to make the test, the lengthy duration of the same and the high loads between the screw and the frame that holds it. The article describes the test rig designed scheme, the kinematic expedients to be adopted in order to obtain the required performance and functionality and the sizing procedure to choose the actuation system.

  12. Role of the RIG-I-like receptors in antiviral response

    Directory of Open Access Journals (Sweden)

    Agnieszka Jabłońska

    2014-01-01

    Full Text Available The innate nonspecific immunity is the first line of defense against viral infection. Toll-like receptors (TLRs and retinoic acid-inducible gene I (RIG-I-like receptors (RLRs are two main receptor families detecting viral nucleic acid. So far, three RLR family members were characterized: RIG-I, MDA5 and LGP2. RLR constitute a family of cytoplasmic helicases, which recognized intracellular single-stranded and double-stranded RNA that is introduced to cytosol during viral infection and replication. In this work we review the current knowledge about the mechanisms of viral recognition by RIG-I-like receptors and their signaling pathways for the activation of type I interferons and pro-inflammatory cytokines synthesis.

  13. Exp-function method for solving Maccari's system

    International Nuclear Information System (INIS)

    Zhang Sheng

    2007-01-01

    In this Letter, the Exp-function method is used to seek exact solutions of Maccari's system. As a result, single and combined generalized solitonary solutions are obtained, from which some known solutions obtained by extended sine-Gordon equation method and improved hyperbolic function method are recovered as special cases. It is shown that the Exp-function method provides a very effective and powerful mathematical tool for solving nonlinear evolution equations in mathematical physics

  14. Saving money on rig refurbishments through foreign trade zones or duty-drawback

    International Nuclear Information System (INIS)

    Ward, R.J. Jr.

    1997-01-01

    The recent boom in day rates for rigs capable of drilling in deep water and harsh environments has created a frenzy of rig refurbishment activity in shipyards located in US Gulf states. In most instances, the destination for the rigs upon completion is the US Outer Continental Shelf (USOCS) in the Gulf of Mexico. The problem faced by contractors/operators planning to use US shipyards is that this circumstance has caused difficulty in shielding rigs and their foreign-sourced components from US Customs duties. Under US Customs law, a bona fide exportation requires severance from US commerce and joining to the commerce of some foreign country or, in the case of a vessel supply, a qualifying international voyage. The USOCS does not qualify as an exportation, nor do movements to drilling sites located on it qualify as an international voyage. Described here are two possible solutions to this economic dilemma and an example of how the foreign trade zone solution was applied by Global marine in its plans for upgrading some of its semisubmersible drilling rigs for deepwater USOCS work

  15. TITAN - a 9 MW, 179 bar pressurised water rig

    International Nuclear Information System (INIS)

    Mogford, D.J.; Lee, D.H.

    1987-02-01

    The report describes the TITAN rig built at Winfrith for thermal hydraulic experiments with water at up to 179 bar pressure. A power supply of 9 MW is available. The report describes three typical experiments that show the versatility of the rig. The first is a 25 rod pressurized water reactor fuel bundle critical heat flux experiment, the second is a parallel channel evaporator test and the third is a model jet pump test. (author)

  16. Demonstration of various rotor instabilities (exhibit of Bently Rotor Dynamics Research Corporation Laborator rigs at symposium on instability in rotaing machinery)

    Science.gov (United States)

    Muszynska, A.

    1985-01-01

    The operation of rotor rigs used to demonstrate various instability phenomena occurring in rotating machines is described. The instability phenomena demonstrated included oil whirl/whip antiswirl, rub, loose rotating parts, water-lubricated bearing instabilities, and cracked shaft. The rotor rigs were also used to show corrective measures for preventing instabilities. Vibrational response data from the rigs were taken with modern, computerized instrumentation. The rotor nonsynchronous perturbation rig demonstrated modal identification techniques for rotor/bearing systems. Computer-aided data acquisition and presentation, using the dynamic stiffness method, makes it possible to identify rotor and bearing parameters for low modes. The shaft mode demonstrator presented the amplified modal shape line of the shaft excited by inertia forces of unbalance (synchronous perturbation). The first three bending modes of the shaft can be demonstrated. The user-friendly software, Orbits, presented a simulation of rotor precessional motion that is characteristic of various instability phenomena. The data presentation demonstration used data measured on a turbine driven compressor train as an example of how computer aided data acquisition and presentation assists in identifying rotating machine malfunctions.

  17. Speeding up : new Atlas Copco rig meant to cut non-drilling time

    Energy Technology Data Exchange (ETDEWEB)

    Roche, P.

    2009-06-15

    Automation has significantly reduced the time needed to drill shallow to medium-depth wells. The time it takes for a drill to reach the production zone is decreasing because newly developed hydraulic systems are able to maintain a constant pace. However, a great deal of time is still consumed by demobilization, transportation and setting up to drill the next well. Atlas Copco Drilling Solutions, a Swedish-based global maker of industrial equipment such as mining and mineral exploration rigs, designed a new Predator drilling system that consists of a mobile rig, a substructure and a pipe-handling skate. The Predator drilling system reduces non-drilling time and the associated costs. This article described the design of this new drilling system with particular reference to how it combines the mobile rig, the substructure and the pipe-handling skate into a three-load package. In order to reduce rig weight and improve mobility, the system is designed so that the table, master bushing, hydraulic slips and iron roughneck are part of the substructure that travel together. The rig has a working hook load capacity of 200,000 pounds, translating into a nominal depth capacity of 8,000 to 10,000 feet. The article also described the mounting of the rig, maneuverability, hydraulic control, and pipe-handling safety. Its various components were also described. 1 ref., 1 fig.

  18. In Situ Measurement of Discomfort Curves for Seated Subjects in a Car on the Four-Post Rig

    Directory of Open Access Journals (Sweden)

    T. Ibicek

    2014-01-01

    Full Text Available The aim of this study is to measure and quantify perceived intensity of discomfort due to vibration in a vehicle in situ considering complete vehicle dynamic behaviour. The shaker table based discomfort curves or the road test results may not accurately and universally indicate the true level of human discomfort in a vehicle. A new experimental method, using a seated human in a car on the four-post rig simulator, is proposed to quantify discomfort. The intensity of perception to vibration decreased with decreasing input and increasing frequency; the rate of change is different from the published literature; the difference is large for angular modes of inputs. Vehicle dynamic response is used to inform and analyse the results. The repeatability of the method and the fact that they are in situ measurements may eventually help reduce reliance on the road tests. Furthermore, discomfort curves obtained, subsequently, can be used in predictive models.

  19. Robotics Test Rig

    International Nuclear Information System (INIS)

    Schuurmans, P.

    2007-01-01

    The experimental Accelerator Driven System XT-ADS is being developed within the European 6th framework programme EUROTRANS using the MYRRHA DRAFT-2 as starting point. The aim for the XT-ADS is to demonstrate the feasibility of the ADS concept at reasonable power levels and to serve as a high performance, multi-purpose experimental irradiation device. One of the fundamental design options that has been taken is to do all maintenance and in-service inspection and repair duties by remote handling. Outside the XT-ADS vessel in a controlled though radio-active environment, remote handling concepts as those already in use at e.g. the Joint European Torus (JET) can be used. Extrapolation to remote handling inside the lead-bismuth eutectic filled main vessel of the XT-ADS is in principle feasible as was shown in a 2003 study performed by Oxford Technologies ltd for the case of MYRRHA. Nevertheless, it is clear that all critical remote handling components need to be qualified for use in liquid LBE. Thus, as a first step, a proof of principle (POP) experimental test rig is require. The principal goal of this work is to identify the critical technological issues that must be resolved to allow operation of remote handling manipulators inside the LBE filled main vessel of the XT-ADS and to propose a concept design and specification catalogue for a proof of principle test rig that is able to experimentally verify the main aspects of manipulator design

  20. Influência de aderências peritoneais e fio cirúrgico na tensão de ruptura da parede abdominal em ratos

    Directory of Open Access Journals (Sweden)

    Roberto Martins Gonçalves

    Full Text Available O resultado de operações na cavidade abdominal pode ser influenciado por aderências. Existem muitos conceitos ainda não comprovados sobre os efeitos das aderências na resistência de suturas tanto de vísceras intracavitárias quanto da parede abdominal. O presente trabalho visa a avaliar a influência das aderências peritoneais e vários tipos de fios cirúrgicos na tensão de ruptura da parede abdominal. Em 60 ratos Wistar, realizou-se laparotomia de 5cm de comprimento. A parede muscular e o peritônio foram fechados em plano único, com pontos simples, usando aleatoriamente os fios de náilon monofilamentar, ácido poliglicólico, categute simples e categute cromado, todos 4-0. Os animais foram divididos em três grupos: 1- Controle; 2- INTRODUÇÃO de 0,3g de talco dentro da cavidade abdominal; 3- Acréscimo de carboximetilcelulose sódica (CMC juntamente com o talco. Houve a análise dos grupos com sete e 21 dias. Avaliou-se o grau de aderências e a tensão de ruptura da ferida cirúrgica. A CMC reduziu a formação de aderências provocadas pelo talco (p<0,01. Houve diferença na tensão de ruptura quando comparados os grupos de sete e 21 dias (p<0,05. As aderências proporcionaram uma maior força tênsil à ferida (p<0,01. O tipo de fio utilizado não influenciou na tensão de ruptura a longo prazo. Portanto, as aderências aumentaram a força tênsil dos tecidos e o tipo de fio cirúrgico não influenciou nesse processo.

  1. Testing of elastomer seals using small-size rigs

    International Nuclear Information System (INIS)

    Leeks, C.W.E.; Dunford, B.; Barnfield, J.H.; Gray, I.L.S.

    1997-01-01

    This paper looks at the use of small size seal leakage test rigs to demonstrate the compliance of full size container seals against the IAEA Transport Regulation's limits for activity release for normal transport and accident conditions. The detailed requirements of the regulations are discussed and it is concluded that an appropriate test programme to meet these requirements using only small size test rigs, can normally be set up and carried out on a relatively short time scale. It is important that any small test rigs should be designed to represent the relevant features of the seal arrangement and the overall test programme should cover all of the conditions, specified by the regulations, for the type, classification and contents of the container under consideration. The parameters of elastomer O-rings, which affect their sealing ability, are considered and those which are amenable to small scale testing or have to be modelled at full size are identified. Generally, the seals used in leakage tests have to be modelled with a full size cross-section but can have a reduced peripheral length. (Author)

  2. The Hydraulic Test Procedure for Non-instrumented Irradiation Test Rig of Annular Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dae Ho; Lee, Kang Hee; Shin, Chang Hwan; Park, Chan Kook

    2008-08-15

    This report presents the procedure of pressure drop test, vibration test and endurance test for the non-instrumented rig using the irradiation test in HANARO of advanced PWR annular fuel which were designed and fabricated by KAERI. From the out-pile thermal hydraulic tests, confirm the flow rate at the 200 kPa pressure drop and measure the RMS displacement at this time. And the endurance test is confirmed the wear and the integrity of the non-instrumented rig at the 110% design flow rate. This out-pile test perform the Flow-Induced Vibration and Pressure Drop Experimental Tester(FIVPET) facility. The instruments in FIVPET facility was calibrated in KAERI and the pump and the thermocouple were certified by manufacturer.

  3. Automatic X-ray television rig for high-speed radiography of polycrystals

    International Nuclear Information System (INIS)

    Bezbakh, V.D.; Garasim, Yu.A.; Oshkaderov, S.P.; Pet'kov, V.V.

    1993-01-01

    The high-speed radiography method is used for studying the phase and structural transformation in metals and alloys during rapid changes in temperature. In order to improve the effectiveness of this method the Institute of Metal Physics, Ukrainian Academy of Sciences, has developed an automatic rig for high-speed radiography of polycrystalline materials using a television method for recording the x-ray diffraction patterns. The rig, described here, consists of an x-ray block, a vacuum chamber, a device for programmed electro-contact heating of specimens, a system for imaging and scanning x-ray diffraction patterns, and a system for collecting and analyzing the data. Focusing is carried out by the Zeeman-Bolin method. The new rig helps to significantly reduce the recording time and ensures adequate quality and reliability of the recorded diffraction image over a wide range of temperatures. Data using the rig is presented for high-speed radiography for cooling a specimen of G20 steel. 4 refs., 4 figs

  4. Analysis of rig test data for an axial/centrifugal compressor in the 12 kg/sec

    Science.gov (United States)

    Owen, A. K.

    1994-01-01

    Extensive testing was done on a T55-L-712 turboshaft engine compressor in a compressor test rig at TEXTRON/Lycoming. These rig tests will be followed by a series of engine tests to occur at the NASA Lewis Research Center beginning in the last quarter of 1993. The goals of the rig testing were: (1) map the steady state compressor operation from 20 percent to 100 percent design speed, (2) quantify the effects of compressor bleed on the operation of the compressor, and (3) explore and measure the operation of the compressor in the flow ranges 'beyond' the normal compressor stall line. Instrumentation consisted of 497 steady state pressure sensors, 153 temperature sensors and 34 high response transducers for transient analysis in the pre- and post-stall operating regime. These measurements allow for generation of detailed stage characteristics as well as overall mapping. Transient data is being analyzed for the existence of modal disturbances at the front face of the compression system ('stall precursors'). This paper presents some preliminary results of the ongoing analysis and a description of the current and future program plans. It will primarily address the unsteady events at the front face of the compression system that occur as the system transitions from steady state to unsteady (stall/surge) operation.

  5. PNNL Hoisting and Rigging Manual

    Energy Technology Data Exchange (ETDEWEB)

    Haynie, Todd O.; Fullmer, Michael W.

    2008-12-29

    This manual describes the safe and cost effective operation, inspection, maintenance, and repair requirements for cranes, hoists, fork trucks, slings, rigging hardware, and hoisting equipment. It is intended to be a user's guide to requirements, codes, laws, regulations, standards, and practices that apply to Pacific Northwest National Laboratory (PNNL) and its subcontractors.

  6. A Dynamic Behavior of the Nuclear Test Rig with Coolant using the Fluid-Structural interaction Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Tae-Ho; Hong, Jintae; Ahn, Sung-Ho; Joung, Chang-Young; Jang, Seo-Yun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Yeon, Kon-Whi [Chungnam National University, Daejeon (Korea, Republic of)

    2016-10-15

    In this paper, the dynamic behavior of the test rig in the coolant flow simulator is evaluated by using the 2-way fluid-structural interaction analysis. The maximum value and location of the deformation and equivalent stress in the test rig is confirmed. The fluid-structural interaction analysis is applied to perform the fluid and structural analysis A fluid-structure interaction analysis is used to simulate the relationship between the deformation and hydraulic pressure. There are two types of fluid-structural interaction analysis. One is a 1-way direction analysis in which the hydraulic pressure is calculated by a CFD and transmitted to the surface of the structure, and a structural analysis is then performed. The other is a 2-way direction analysis that is performed by changing the data between the deformation of the structural and pressure of the coolant water for every time step. The location of the maximum deformation of the test rig is the bottom parts of the test rig. It is expected that the equivalent stress of the test rig is occurred. The maximum equivalent stress in the test rig under the circulation of the coolant is 90.1 MPa. The location of the maximum stress in the test rig is the connect part between the fuel rod and flow divider. A safety factor on the test rig is 3, approximately. The deformation motion of the test rig at the bottom part of the test rig is caused about the fluid-induced vibration. A test on the fluid-induced vibration of the test rig will be performed and compared with results of the analysis in further paper.

  7. Pigeon RIG-I Function in Innate Immunity against H9N2 IAV and IBDV

    Directory of Open Access Journals (Sweden)

    Wenping Xu

    2015-07-01

    Full Text Available Retinoic acid-inducible gene I (RIG-I, a cytosolic pattern recognition receptor (PRR, can sense various RNA viruses, including the avian influenza virus (AIV and infectious bursal disease virus (IBDV, and trigger the innate immune response. Previous studies have shown that mammalian RIG-I (human and mice and waterfowl RIG-I (ducks and geese are essential for type I interferon (IFN synthesis during AIV infection. Like ducks, pigeons are also susceptible to infection but are ineffective propagators and disseminators of AIVs, i.e., “dead end” hosts for AIVs and even highly pathogenic avian influenza (HPAI. Consequently, we sought to identify pigeon RIG-I and investigate its roles in the detection of A/Chicken/Shandong/ZB/2007 (H9N2 (ZB07, Gansu/Tianshui (IBDV TS and Beijing/CJ/1980 (IBDV CJ-801 strains in chicken DF-1 fibroblasts or human 293T cells. Pigeon mRNA encoding the putative pigeon RIG-I analogs was identified. The exogenous expression of enhanced green fluorescence protein (EGFP-tagged pigeon RIG-I and caspase activation and recruitment domains (CARDs, strongly induced antiviral gene (IFN-β, Mx, and PKR mRNA synthesis, decreased viral gene (M gene and VP2 mRNA expression, and reduced the viral titers of ZB07 and IBDV TS/CJ-801 virus strains in chicken DF-1 cells, but not in 293T cells. We also compared the antiviral abilities of RIG-I proteins from waterfowl (duck and goose and pigeon. Our data indicated that waterfowl RIG-I are more effective in the induction of antiviral genes and the repression of ZB07 and IBDV TS/CJ-801 strain replication than pigeon RIG-I. Furthermore, chicken melanoma differentiation associated gene 5(MDA5/ mitochondrial antiviral signaling (MAVS silencing combined with RIG-I transfection suggested that pigeon RIG-I can restore the antiviral response in MDA5-silenced DF-1 cells but not in MAVS-silenced DF-1 cells. In conclusion, these results demonstrated that pigeon RIG-I and CARDs have a strong antiviral

  8. Technical and economic evaluation of selected compact drill rigs for drilling 10,000 foot geothermal production wells

    Energy Technology Data Exchange (ETDEWEB)

    Huttrer, G.W. [Geothermal Management Company, Inc., Frisco, CO (United States)

    1997-11-01

    This report summarizes the investigation and evaluation of several {open_quotes}compact{close_quotes} drill rigs which could be used for drilling geothermal production wells. Use of these smaller rigs would save money by reducing mobilization costs, fuel consumption, crew sizes, and environmental impact. Advantages and disadvantages of currently-manufactured rigs are identified, and desirable characteristics for the {open_quotes}ideal{close_quotes} compact rig are defined. The report includes a detailed cost estimate of a specific rig, and an evaluation of the cost/benefit ratio of using this rig. Industry contacts for further information are given.

  9. BURNER RIG TESTING OF A500 C/SiC

    Science.gov (United States)

    2018-03-17

    AFRL-RX-WP-TR-2018-0071 BURNER RIG TESTING OF A500® C /SiC Larry P. Zawada Universal Technology Corporation Jennifer Pierce UDRI...TITLE AND SUBTITLE BURNER RIG TESTING OF A500® C /SiC 5a. CONTRACT NUMBER In-House 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62102F 6...test program characterized the durability behavior of A500® C /SiC ceramic matrix composite material at room and elevated temperature. Specimens were

  10. On an integral representation of the function Tr(exp(A-lambdaB))

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, M L [CEA Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Service de Physique Theorique; Kumar, K

    1976-02-01

    The conjecture that Tr(exp(A-lambdaB)) can be written as a Laplace transform with a positive measure is proved for a certain class of matrices A and B. A few remarks are made about the undecided cases.

  11. A study of the modes of advancement of multiple drilling rigs and the influence of the inertial effects on the efficiency of the towers

    Energy Technology Data Exchange (ETDEWEB)

    Karapetyan, K.V.

    1979-01-01

    Studied in a mathematical model with the use of experimental data obtained through a method of measurement filming is the process of advancement of a drilling rig and the inertial actions on the drilling equipment are determined. It is shown that the tower type rigs, the VM-41 may be safely advanced along with the package of drilling stands. For mast rigs, suitable for conditions of multiple drilling, the creation of special drive mechanisms with high travel smoothness is recommended.

  12. Testing of a new morphing trailing edge flap system on a novel outdoor rotating test rig

    DEFF Research Database (Denmark)

    Aagaard Madsen, Helge; Barlas, Athanasios; Løgstrup Andersen, Tom

    2015-01-01

    The morphing trailing edge system or flap system, CRTEF, has been developed over the last 10 years at DTU Wind Energy. After a promising wind tunnel test of the system in 2009 the INDUFLAP project has been carried out from 2011-2014 to transfer the technology from laboratory to industrial...... manufacturing and application. To narrow the gap between wind tunnel testing and full scale prototype testing we developed the rotating test rig. The overall objectives with the rotating test rig are: 1) to test the flap system in a realistic rotating environment with a realistic g-loading; 2) to measure...... the flap performance in real turbulent inflow and 3) to test the flap system in a realistic size and Reynolds number when comparing with full scale applications.. The rotating test rig consists of a 2.2m blade section attached to a 10m boom and mounted on a 100kW turbine platform. It was installed in June...

  13. 48 CFR 18.118 - Trade agreements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Trade agreements. 18.118 Section 18.118 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES EMERGENCY ACQUISITIONS Available Acquisition Flexibilities 18.118 Trade agreements...

  14. Stochastic programming of drilling rigs supplies; Programacao estocastica de suprimentos de sondas

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Bruno Ferreira; Ferreira Filho, Virgilio Jose Martins [Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE/UFRJ), RJ (Brazil)

    2012-07-01

    The goal of this work is to use techniques of stochastic programming to reduce logistic costs regarding offshore drilling rigs. This theme is of great interest to Brazilian oil industry since there is an increasing number of wells that need to be perforated so that Brazilian oil production can reach its expected growth over the next ten years (PETROBRAS in particular has an ambitious strategy in this respect). Proper treatment of the uncertainties involved in the deliveries of supplies to offshore drilling rigs is essential, namely, these uncertainties need to be included in the models used in logistic models. Delays in the deliveries of products such as chemicals, perforation fluids and tubes may force drilling rigs to stop their operations what highly increases costs. The daily hiring rates of drilling rigs represent the highest cost in the perforation and completion of a well. (author)

  15. Substantial Fatigue Similarity of a New Small-Scale Test Rig to Actual Wheel-Rail System

    NARCIS (Netherlands)

    Naeimi, M.; Li, Z.; Petrov, R.H.; Dollevoet, R.P.B.J.; Sietsma, J.; Wu, J.

    2014-01-01

    The substantial similarity of fatigue mechanism in a new test rig for rolling contact fatigue (RCF) has been investigated. A new reduced-scale test rig is designed to perform controlled RCF tests in wheel-rail materials. The fatigue mechanism of the rig is evaluated in this study using a combined

  16. Work over rig itinerary optimization; Otimizacao do itinerario de sondas de intervencao

    Energy Technology Data Exchange (ETDEWEB)

    Paiva, Ronaldo Oliveira de

    1997-07-01

    The costs of work over and the loss of revenue in wells waiting work over rigs are very high. This work proposes methods to prioritize these wells in order to minimize the total cost. To determine the work over sequence it is necessary to compare the rig expense with the wells losses. For calculating the wells losses, it is necessary to analyze the monetary influence of the well shutdown in the production curves. In this work, this analysis is made by using a numerical reservoir simulator. Simplified calculation procedures are also presented. The priority of the wells is based on the reduction of the total cost, which consists of the rig costs plus the revenue losses due to work over waiting. There are many algorithms able to determine the ideal rig path. Simple and intuitive algorithms are implemented and compared. The Simulated Annealing algorithm is recommended. This algorithm was implemented to optimize work over rig routes in a brazilian production region. Optimization of the work over sequence carried out in that region in 1996 identified a potential economy of 15% in the production losses, equivalent to 4.000m{sup 3}/year of oil (25.000 b bl/year). (author)

  17. Transreceptor de faixa larga baseado em impulso de rádio para sensor sem fios de curta distância implementado em tecnologia CMOS

    OpenAIRE

    Rodrigues, David Manuel Cardoso

    2013-01-01

    Dissertação para obtenção do Grau de Mestre em Engenharia Electrotécnica e de Computadores O rápido desenvolvimento da microtecnologia e microelectrónica tem vindo a contribuir de forma decisiva para uma crescente utilização de sensores, sejam eles com ou sem fios, o que permitirá interagir mais eficientemente com o meio envolvente, em consequência de mais e melhor medição e atuação. Neste contexto, as redes de sensores sem fios (WSNs) estão a emergir como uma das grandes e mais impo...

  18. Development of TIG Welding System for a Nuclear Fuel Test Rig

    Energy Technology Data Exchange (ETDEWEB)

    Joung, Changyoung; Ahn, Sungho; Hong, Jintae; Kim, Kahye [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    The welding process is one of the most important among the instrumentation processes of the nuclear fuel test rig and rods. To manufacture the nuclear fuel test rig, a precision welding system needs to be fabricated to develop various welding technologies of the fuel test rig and rods jointing the various sensors and end caps on a fuel cladding tube, which is charged with fuel pellets and component parts. Thus, we designed and fabricated the precision welding system consisting of an orbital TIG welder, a low-pressure chamber, and a high-pressure chamber. Using this system, the performance tests were performed with the round and seal spot welds for each welding condition. This paper describes not only the contents for the fabrication of precision TIG welding system but also some results from weld tests using the low-pressure and high-pressure chambers to verify the performance of this system. The TIG welding system was developed to manufacture the nuclear fuel test rig and rods. It has been configured to be able to weld the nuclear fuel test rigs and rods by applying the TIG welder using a low-pressure chamber and a high-pressure chamber. The performance tests using this system were performed with the round and seal spot welds for the welding conditions. The soundness of the orbital TIG welding system was confirmed through performance tests in the low-pressure and high-pressure chambers.

  19. Development of TIG Welding System for a Nuclear Fuel Test Rig

    International Nuclear Information System (INIS)

    Joung, Changyoung; Ahn, Sungho; Hong, Jintae; Kim, Kahye

    2013-01-01

    The welding process is one of the most important among the instrumentation processes of the nuclear fuel test rig and rods. To manufacture the nuclear fuel test rig, a precision welding system needs to be fabricated to develop various welding technologies of the fuel test rig and rods jointing the various sensors and end caps on a fuel cladding tube, which is charged with fuel pellets and component parts. Thus, we designed and fabricated the precision welding system consisting of an orbital TIG welder, a low-pressure chamber, and a high-pressure chamber. Using this system, the performance tests were performed with the round and seal spot welds for each welding condition. This paper describes not only the contents for the fabrication of precision TIG welding system but also some results from weld tests using the low-pressure and high-pressure chambers to verify the performance of this system. The TIG welding system was developed to manufacture the nuclear fuel test rig and rods. It has been configured to be able to weld the nuclear fuel test rigs and rods by applying the TIG welder using a low-pressure chamber and a high-pressure chamber. The performance tests using this system were performed with the round and seal spot welds for the welding conditions. The soundness of the orbital TIG welding system was confirmed through performance tests in the low-pressure and high-pressure chambers

  20. Intra-abdominal recurrence of colorectal cancer detected by radioimmunoguided surgery (RIGS system)

    International Nuclear Information System (INIS)

    Sardi, A.; Workman, M.; Mojzisik, C.; Hinkle, G.; Nieroda, C.; Martin, E.W. Jr.

    1989-01-01

    Since 1986, 32 patients with metastatic colorectal cancer have undergone second-look radioimmunoguided surgery (RIGS system). The primary tumor was located in the right and transverse colon in 11 patients, left and sigmoid colon in 16, and rectum in five. The carcinoembryonic antigen level was elevated in 30 patients (94%); all patients underwent a computed tomographic scan of the abdomen and pelvis. The overall sensitivity of the computed tomographic scan was 41% (abdomen other than liver, 27%; liver, 58%; and pelvis, 22%). The RIGS system identified recurrent tumor in 81% of the patients. The most common site of metastasis was the liver (41%), independent of the primary location. Local/regional recurrences alone accounted for 40% of all recurrences. In six patients (18%), recurrent tumor was found only with the RIGS system. The RIGS system is more dependable in localizing clinically obscure metastases than other methods, and carcinoembryonic antigen testing remains the most accurate preoperative method to indicate suspected recurrences

  1. Finite element calculation of fields around the end region of a turbine generator test rig

    Energy Technology Data Exchange (ETDEWEB)

    Eastham, J.F.; Rodger, D.; Lai, H.C.; Nouri, H. (Univ. of Bath (United Kingdom))

    1993-03-01

    Under transient conditions, most often caused by faults in the power system, unbalanced load is presented to a turbine generator. This gives rise to airgap fields which do not travel at the speed of the rotor, and cause induced currents which occur in the solid steel surface. This can cause high local heating. The current path is generally in the axial direction of the machine but the distribution in the end region is not so well known. Here, comparisons are drawn between the use of surface impedance elements and volume elements when modeling a test rig using the MEGA package. The test rig is representative of a turbine generator. The work is supported by practical measurements.

  2. Computer aided extractor design for the RIG 10 high intensity ion source

    International Nuclear Information System (INIS)

    Tanzer, F.; Haeuser, J.; Eppel, D.

    1980-01-01

    The paper discusses recent progress of the rf-ion source RIG 10, and describes a computer code for the simulation of the ion trajectories. The RIG 10 is designed for current densities of some 300 mA/cm 2 , and will be used for the production of neutral. (orig.)

  3. 33 CFR 118.130 - Fog signals.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Fog signals. 118.130 Section 118... LIGHTING AND OTHER SIGNALS § 118.130 Fog signals. On waterways where visibility is frequently reduced due to fog or other causes, the District Commander may require or authorize the installation of one or...

  4. This immortal coil? New CT rigs duel against singles

    Energy Technology Data Exchange (ETDEWEB)

    Creighton, J.

    1998-12-01

    New competition to conventional single rigs that have changed little in the last four decades face new competition from next-generation coiled tubing (CT) units which have multi-function capabilities, ranging from driving onto leases, drilling and setting surface case to cementing. Several of these new units are ready to challenge the conventional single rigs. Their ability to perform at high penetration rates (up to twice what single rigs can do) is expected to significantly cut drill time, with corresponding cost savings for both contractors and operators. Serval Corporation and Fleet Coiled Services are just two of the drilling service companies that have launched new shallow grass roots coiled tubing drilling units recently, gambling that the new technology will win over conventional methods hands down. Some major companies, like Fracmaster Ltd. and NOWSCO Well Service Ltd., have targeted the re-entry and horizontal markets, a much more difficult technical challenge, sinking billions of dollars of research and development money into advancing the most technically difficult applications of coil technology.

  5. 45 CFR 400.118 - Case planning.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Case planning. 400.118 Section 400.118 Public... Services § 400.118 Case planning. (a) A State, or its designee under § 400.117, must develop and implement... services. (b) Case planning for unaccompanied minors must, at a minimum, address the following elements: (1...

  6. 46 CFR 118.600 - Fire axe.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire axe. 118.600 Section 118.600 Shipping COAST GUARD... OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS FIRE PROTECTION EQUIPMENT Additional Equipment § 118.600 Fire axe. A vessel of more than 19.8 meters (65 feet) in length must have at least one fire axe...

  7. 46 CFR 118.400 - Where required.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Where required. 118.400 Section 118.400 Shipping COAST... Extinguishing and Detecting Systems § 118.400 Where required. (a) The following spaces must be equipped with a... unoccupied space with a gross volume of not more than 170 cubic meters (6,000 cubic feet); (2) A pre...

  8. Slant rigs offer big payoffs in shallow drilling

    International Nuclear Information System (INIS)

    Smith, J.; Edwards, B.

    1992-01-01

    Slant hole drilling technology can result in considerable savings over conventionally drilled deviated holes because mud motors and deviation control with measurement while drilling tools are usually unnecessary. The benefits of using slant hole rigs for development drilling improve after the bit walk tendencies and the correct bottom hole assemblies have been determined for a particular area. This article discusses three recent drilling operations that successfully used slant drilling technology on land-based projects: drilling for heavy oil in Alberta, drilling for gas in Alberta, and drilling a river crossing for a gas pipeline in British Columbia. These examples demonstrate the flexibility of slant drilling technology

  9. Modelling and simulation of dynamic wheel-rail interaction using a roller rig

    International Nuclear Information System (INIS)

    Anyakwo, A; Pislaru, C; Ball, A; Gu, F

    2012-01-01

    The interaction between the wheel and rail greatly influences the dynamic response of railway vehicles on the track. A roller rig facility can be used to study and monitor real time parameters that influence wheel-rail interaction such as wear, adhesion, friction and corrugation without actual field tests being carried out. This paper presents the development of the mathematical models for full scale roller rig and 1/5 scale roller rig and the wear prediction model based on KTH wear function. The simulated critical speed for the 1/5 scale roller rig is about one-fifth of the critical speed for the full scale model so the simulated results compare well with the theory related to wheel-rail contact and dynamics. Also the differences between the simulated rolling radii for the full scale model with and without wear function are analysed. This paper presents the initial stage of a large scale research project where the influence of wear on the wheel-rail performance will be studied in more depth.

  10. RIG-1 expression is associated with sexual malfunctions of female type 2 diabetic patients

    Directory of Open Access Journals (Sweden)

    Batool Hajebrahimi

    2017-03-01

    Full Text Available Introduction: The patients with type 2 diabetes (T2D suffer from the malfunctions of the sexual behaviors, and several mechanisms have been proposed to describe these disorders. The innate immunity may be involved in the malfunctions of T2D patients. Melanoma differentiation-associated protein 5 (MDA5 and retinoic acid (RA-inducible gene 1 (RIG-1, as the innate immunity receptors, are the responsible molecules for the activation of some intracellular signaling pathways and the induction of inflammation. Thus, this study aimed to examine the molecules which may participate in the induction/stimulation of sexual malfunctions in the female T2D patients. Methods: Sexual functions were evaluated in 41 female T2D patients using the Female Sexual Function Index (FSFI questionnaire. Real-time polymerase chain reaction (PCR technique was used to quantify MDA5 and RIG-1 mRNA levels. Results: Results showed that increased RIG-1 mRNA levels were significantly associated with the bad orgasm in the female T2D patients compared to the female patients with good orgasm. Expression of RIG-1 and MDA5 levels were not associated with other sexual functions’ criteria. Conclusion: The findings of this study demonstrated that bad orgasm is associated with the increased RIG-1 expression. Consequently, the correlation between inflammation and bad orgasm in a RIG-1 dependent manner is suggested.

  11. Tractor accelerated test on test rig

    Directory of Open Access Journals (Sweden)

    M. Mattetti

    2013-09-01

    Full Text Available The experimental tests performed to validate a tractor prototype before its production, need a substantial financial and time commitment. The tests could be reduced using accelerated tests able to reproduce on the structural part of the tractor, the same damage produced on the tractor during real life in a reduced time. These tests were usually performed reproducing a particular harsh condition a defined number of times, as for example using a bumpy road on track to carry out the test in any weather condition. Using these procedures the loads applied on the tractor structure are different with respect to those obtained during the real use, with the risk to apply loads hard to find in reality. Recently it has been demonstrated how, using the methodologies designed for cars, it is possible to also expedite the structural tests for tractors. In particular, automotive proving grounds were recently successfully used with tractors to perform accelerated structural tests able to reproduce the real use of the machine with an acceleration factor higher than that obtained with the traditional methods. However, the acceleration factor obtained with a tractor on proving grounds is in any case reduced due to the reduced speed of the tractors with respect to cars. In this context, the goal of the paper is to show the development of a methodology to perform an accelerated structural test on a medium power tractor using a 4 post test rig. In particular, several proving ground testing conditions have been performed to measure the loads on the tractor. The loads obtained were then edited to remove the not damaging portion of signals, and finally the loads obtained were reproduced in a 4 post test rig. The methodology proposed could be a valid alternative to the use of a proving ground to reproduce accelerated structural tests on tractors.

  12. Wythenshawe boiler rig. Thirty years of support to the UK nuclear power industry

    International Nuclear Information System (INIS)

    Rudge, Andy; Woolsey, Ian S.; Moore, Andrew

    2010-01-01

    The Wythenshawe Boiler Rig in Manchester, UK, recently celebrated thirty years of operation in support of the UK nuclear power industry. The Boiler Rig, owned by EDF Energy and operated on EDF Energy's behalf by Serco plc, is a full scale once-through boiler test facility for the investigation of chemistry and corrosion related topics. This paper presents an overview of the design and operation of the Boiler Rig together with some of the technical highlights from its thirty years of operation, many of which have relevance to power plant operations beyond those plants for which the work was performed. (orig.)

  13. Stress-life relation of the rolling-contact fatigue spin rig

    Science.gov (United States)

    Butler, Robert H; Carter, Thomas L

    1957-01-01

    The rolling-contact fatigue spin rig was used to test groups of SAE 52100 9.16-inch-diameter balls lubricated with a mineral oil at 600,000-, 675,000-, and 750,000-psi maximum Hertz stress. Cylinders of AISI M-1 vacuum and commercial melts and MV-1 (AISI M-50) were used as race specimens. Stress-life exponents produced agree closely with values accepted in industry. The type of failure obtained in the spin rig was similar to the subsurface fatigue spells found in bearings.

  14. Out-of-pile burnout experiments in a full-scale simulation of an irradiation rig in a HIFAR hollow fuel element facility

    International Nuclear Information System (INIS)

    Chapman, A.G.; Hargreaves, N.D.

    1986-06-01

    Flow measurement and burnout experiments were performed in an out-of-pile test rig which simulates the conditions of UO 2 irradiation rig in a hollow fuel element facility of the HIFAR reactor. One per cent of the coolant flow in the fuel element passed through the irradiation rig. A burnout heat flux of 90 W cm -2 was observed at the surface of an electrically-heated, dummy irradiation can. When the coolant flow rate in the irradiation rig was increased by a factor of 2.5, the burnout heat flux rose by 30 per cent to 117 W cm -2 . A simple modification to the supporting frame for the cans improved the burnout heat flux by 3 per cent at 1 per cent of the coolant flow, but enhanced it by 17 per cent at 2.5 per cent of the coolant flow. Of ten burnout events observed, eight were located upstream of the end of the heated length of the can. The burnout results form a self-consistent, credible set of data and provide a rational basis for the establishment of maximum permissible operating heat fluxes in irradiation rigs of the type simulated. Recommendations are made for the practical application of the results

  15. 9 CFR 3.118 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  16. Bycatch in 36 and 40 mm PA Turkish twin rigged beam trawl codends

    African Journals Online (AJOL)

    The Turkish twin rigged beam trawl which has two identical nets rigged side by side on the same beam targets mainly the Parapenaeus longirostris, although some bycatch fish species have also become target species. Thus, landings of the shrimp beam trawling fleet also include some commercially valuable fishes.

  17. Toscana virus NSs protein inhibits the induction of type I interferon by interacting with RIG-I.

    Science.gov (United States)

    Gori-Savellini, Gianni; Valentini, Melissa; Cusi, Maria Grazia

    2013-06-01

    Toscana virus (TOSV) is a phlebovirus, of the Bunyaviridae family, that is responsible for central nervous system (CNS) injury in humans. Previous data have shown that the TOSV NSs protein is a gamma interferon (IFN-β) antagonist when transiently overexpressed in mammalian cells, inhibiting IRF-3 induction (G. Gori Savellini, F. Weber, C. Terrosi, M. Habjan, B. Martorelli, and M. G. Cusi, J. Gen. Virol. 92:71-79, 2011). In this study, we investigated whether an upstream sensor, which has a role in the signaling cascade leading to the production of type I IFN, was involved. We found a significant decrease in RIG-I protein levels in cells overexpressing TOSV NSs, suggesting that the nonstructural protein interacts with RIG-I and targets it for proteasomal degradation. In fact, the MG-132 proteasome inhibitor was able to restore IFN-β promoter activation in cells expressing NSs, demonstrating the existence of an evasion mechanism based on inhibition of the RIG-I sensor. Furthermore, a C-terminal truncated NSs protein (ΔNSs), although able to interact with RIG-I, did not affect the RIG-I-mediated IFN-β promoter activation, suggesting that the NSs domains responsible for RIG-I-mediated signaling and interaction with RIG-I are mapped on different regions. These results contribute to identify a novel mechanism for bunyaviruses by which TOSV NSs counteracts the early IFN response.

  18. Freon Rig design for performing to heat transfer experiments for nuclear reactors fuel bundles

    International Nuclear Information System (INIS)

    Flores, L.F.V.

    1981-01-01

    The main features of a Freon Rig design for performing to heat transfer experiments for PWR and BWR fuel bundles, are presented. The project is based on a Freon Rig pressurized at 30 bar with a flow rate up to 80 m 3 /h. The maximum power fed to test sections is of about 420 KW D.C. The rig was designed to use scaling techniques wich would enable a fluid of low latente heat to be used in place of water, thereby reducing the cost of testes. (Author) [pt

  19. Joint test rig for testing and calibrating of different methods of two-phase mass flow measurement

    International Nuclear Information System (INIS)

    Reimann, J.; Arnold, G.; Chung, M.; Hahn, H.; John, H.; Mueller, S.; Wanner, E.

    1977-01-01

    The start-up of the steady-state steam-water loop has been finished. The planned maximal values of the mass flow rate as function of quality and pressure are reached. The components for the steady-state air-water loop have been ordered, the loop has been built up, first function tests have been carried out. Because of the additional work of the extension for air-water flows, the blowdown test rig was delayed. Calculations for the security of the pressure vessel have begun. During the experiments the knowledge of the flow regime and the apparent density is essential. To detect flow regime, impedance probes were developed and have been tested in steam-water flows at pressures up to 150 at. The probe signals can be adjointed to flow patterns even in those cases when high speed movies could not be interpreted definitely. To measure the apparent density a multiple γ-beam densitometer is developed. The collimator block and the mounting support for the γ-source were manufactured, the shielding and cooling of the scintillator has begun. (orig./RW) [de

  20. Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode

    Energy Technology Data Exchange (ETDEWEB)

    Akhrymuk, Ivan; Frolov, Ilya; Frolova, Elena I., E-mail: evfrolova@UAB.edu

    2016-01-15

    Alphaviruses are a family of positive-strand RNA viruses that circulate on all continents between mosquito vectors and vertebrate hosts. Despite a significant public health threat, their biology is not sufficiently investigated, and the mechanisms of alphavirus replication and virus–host interaction are insufficiently understood. In this study, we have applied a variety of experimental systems to further understand the mechanism by which infected cells detect replicating alphaviruses. Our new data strongly suggest that activation of the antiviral response by alphavirus-infected cells is determined by the integrity of viral genes encoding proteins with nuclear functions, and by the presence of two cellular pattern recognition receptors (PRRs), RIG-I and MDA5. No type I IFN response is induced in their absence. The presence of either of these PRRs is sufficient for detecting virus replication. However, type I IFN activation in response to pathogenic alphaviruses depends on the basal levels of RIG-I or MDA5. - Highlights: • Both RIG-I and MDA5 detect alphavirus replication. • Alphavirus-induced transcriptional shutoff affects type I IFN induction. • Sensing of alphavirus replication by RIG-I and MDA5 depends on their concentrations. • High basal level of RIG-I and MDA5 allows IFN induction by pathogenic alphaviruses. • This dependence determines the discrepancy between the in vivo and in vitro data.

  1. 48 CFR 1371.118 - Changes-ship repair.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Changes-ship repair. 1371.118 Section 1371.118 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE DEPARTMENT SUPPLEMENTAL REGULATIONS ACQUISITIONS INVOLVING SHIP CONSTRUCTION AND SHIP REPAIR Provisions and Clauses 1371.118 Changes—ship repair. Insert clause...

  2. 33 CFR 118.140 - Painting bridge piers.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Painting bridge piers. 118.140 Section 118.140 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.140 Painting bridge piers. The District Commander may require...

  3. Efeito da tenacidade da fibra sobre propriedades tecnológicas do fio de algodão Effect of the cotton fiber strength on yarn properties

    Directory of Open Access Journals (Sweden)

    Nelson Paulieri Sabino

    1995-01-01

    Full Text Available Consideraram-se três variedades de algodão com valores de tenacidade da fibra variando de 20,5 a 22,2 g/Tex: IAC 16, IAC 13-1 e IAC 17, classificadas, respectivamente, como de alta, média e baixa tenacidade. Tais variedades apresentaram características tecnológicas semelhantes quanto a comprimento, uniformidade de comprimento, índice de finura Micronaire e maturidade. As amostras foram processadas em estabelecimentos industriais, da maneira convencional, produzindo, cada uma, fios de títulos Ne20, Ne30 e Ne40. Para cada título, empregaram-se sete coeficientes de torção, representados pelas constantes 3,4, 3,6, 3,8, 4,0, 4,2, 4,5 e 4,7. Efetuaram-se as análises da variância dos resultados, de acordo com o delineamento fatorial 3 x 3 x 7, representado pelas três variedades, pelos três títulos e pelos sete níveis de coeficientes de torção. Mediante os resultados, conclui-se que fibras de algodão com alta tenacidade produzem fios mais resistentes e elásticos do que aquelas de baixa tenacidade, para qualquer título ou torção. A quantidade de torções requeridas para a obtenção de máxima resistência dos fios de algodão é pouco afetada pela tenacidade da fibra. Os fios de títulos mais altos têm os menores valores de tenacidade e elongação. A variedade IAC 16 apresentou fios com os maiores valores de tenacidade, seguida da 'IAC 13-1' e da 'IAC 17', e fios mais elásticos, acompanhada da 'IAC 17' e da 'IAC 13-1'.Three cottons with fiber strength of 20.5, 20.9 and 22.2 g/Tex and having other important fiber properties approximately equal were selected. The cottons were processed on conventional processing equipment into 20/1, 30/1 and 40/1 yarn counts, using a range of twist multipliers of 3.4, 3.6, 3.8, 4.0, 4.2, 4.5 and 4.7. Yarn strength and elongation determinations were made on a pendulum-type tester of 150-300 lbs capacity. It was found that: 1 - High strength cotton produced stronger yarns than low strength for any

  4. Rig automation: where it's been and where it's going

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, R.

    1982-06-01

    For over 30 years dreamers, tinkerers and engineers have attempted to automate various drilling functions. Now this effort is paying off, and a partially automated rig is no longer a curiosity. Fully automated and computerized rigs are on the way. For the contractor this means higher productivity, but more maintenance and training responsibilities.

  5. The Winfrith horizontal impact rig

    International Nuclear Information System (INIS)

    Barr, P.

    1985-12-01

    The Horizontal Impact Rig has been designed to allow studies of the impact of radioactive material transport containers and their associated transport vehicles and impact limiters, using large scale models, and to allow physically large missiles to be projected for studying the impact behaviour of metal and concrete structures. It provides an adequately rigid support structure for impact experiments with targets of large dimensions. Details of its design, instrumentation, performance prediction and construction are given. (U.K.)

  6. 33 CFR 118.60 - Characteristics of lights.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Characteristics of lights. 118.60 Section 118.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.60 Characteristics of lights. All lights required or authorized under this...

  7. Development of a low cost test rig for standalone WECS subject to electrical faults.

    Science.gov (United States)

    Himani; Dahiya, Ratna

    2016-11-01

    In this paper, a contribution to the development of low-cost wind turbine (WT) test rig for stator fault diagnosis of wind turbine generator is proposed. The test rig is developed using a 2.5kW, 1750 RPM DC motor coupled to a 1.5kW, 1500 RPM self-excited induction generator interfaced with a WT mathematical model in LabVIEW. The performance of the test rig is benchmarked with already proven wind turbine test rigs. In order to detect the stator faults using non-stationary signals in self-excited induction generator, an online fault diagnostic technique of DWT-based multi-resolution analysis is proposed. It has been experimentally proven that for varying wind conditions wavelet decomposition allows good differentiation between faulty and healthy conditions leading to an effective diagnostic procedure for wind turbine condition monitoring. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  8. TECHNICAL FEATURES OF RIGGED YACHT BY CATEGORIES AND CLASSES

    Directory of Open Access Journals (Sweden)

    Svitlana Yeroshkina

    2016-06-01

    Full Text Available The article is directed on the deeply meaningful scientific study and structural analysis of the technical features of the rigged world modern yachts to pass sailing regattas in different navigation areas. The complete classification of sailing boats in it’s world classes was done for olympic, international, national regattas. It was done the technical indicators of yachting racing classes. The economic analysis material selection sails for yachts are directed of different types of races. In it’s scientific article is made economic calculation of operating cost of the boat and it was done the analysis of cost saving yachts in european / ukrainian marinas.Key words: yachting, rigged yacht, racing, classes of yachts. JEL: L 92

  9. AHP 47: A RIG RGAD PO VISITS LHA SA

    Directory of Open Access Journals (Sweden)

    Pad ma skyid པདྨ་སྐྱིད།

    2017-04-01

    Full Text Available My name is Pad ma skyid. I was born in 1981 in Pan yag Community, 'Bo spa Township, Pad ma County, Mgo log Tibetan Autonomous Prefecture, Mtsho sngon (Qinghai Province. I have eight siblings. Growing up in a black yak-hair tent, we spent our days playing with lambs, foals, and calves. We told all sorts of stories when everyone was in bed - stories about King Ge sar, ghosts, marriages, and tricksters. It was a time for my whole family to relax and share. I heard many A rig rgad po stories from my parents, siblings, and guests. A rig rgad po became part of my childhood. These stories bring back many beautiful memories. ...

  10. Investigation of Solitary wave solutions for Vakhnenko-Parkes equation via exp-function and Exp(-ϕ(ξ))-expansion method.

    Science.gov (United States)

    Roshid, Harun-Or; Kabir, Md Rashed; Bhowmik, Rajandra Chadra; Datta, Bimal Kumar

    2014-01-01

    In this paper, we have described two dreadfully important methods to solve nonlinear partial differential equations which are known as exp-function and the exp(-ϕ(ξ)) -expansion method. Recently, there are several methods to use for finding analytical solutions of the nonlinear partial differential equations. The methods are diverse and useful for solving the nonlinear evolution equations. With the help of these methods, we are investigated the exact travelling wave solutions of the Vakhnenko- Parkes equation. The obtaining soliton solutions of this equation are described many physical phenomena for weakly nonlinear surface and internal waves in a rotating ocean. Further, three-dimensional plots of the solutions such as solitons, singular solitons, bell type solitary wave i.e. non-topological solitons solutions and periodic solutions are also given to visualize the dynamics of the equation.

  11. Implementação de sistemas eólicos para redes de sensores sem fios

    OpenAIRE

    Mendonça, Fábio Rúben Silva

    2015-01-01

    O trabalho tem por objetivo principal estudar a utilização de aerogeradores para microprodução de energia (menor que 1 W) de forma a poderem alimentar os nós das redes de sensores sem fios. Para tal, analisaram-se dois tipos de aerogeradores, os de eixo vertical e os de eixo horizontal, tendo-se efetuado simulações de CFD (Computational Fluid Dynamics) para verificar o desempenho das turbinas, de forma a determinar qual é o mais adequado. Foi realizado o projeto dos dois sistemas e anali...

  12. Roteamento em redes em malha sem fio com balanceamento de carga e caminhos mais curtos

    OpenAIRE

    Mello, Micael Oliveira Massula Carvalho de

    2014-01-01

    Redes em Malha Sem Fio - Wireless Mesh Networks (WMNs) são infraestruturas com propriedades autonômicas, como auto-organização e autorrecuperação, que podem ser implementadas com tecnologias amplamente disponíveis e de custo acessível. Além de suas aplicações atuais, como redes comunitárias e redes de acesso à Internet, as WMNs podem auxiliar na comunicação de Internet das Coisas e constituir infraestruturas robustas para redes inteligentes de energia, dentre outros usos. No en...

  13. The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection.

    Science.gov (United States)

    Ramanathan, Anand; Devarkar, Swapnil C; Jiang, Fuguo; Miller, Matthew T; Khan, Abdul G; Marcotrigiano, Joseph; Patel, Smita S

    2016-01-29

    RIG-I (Retinoic Acid Inducible Gene-I) is a cytosolic innate immune receptor that detects atypical features in viral RNAs as foreign to initiate a Type I interferon signaling response. RIG-I is present in an autoinhibited state in the cytoplasm and activated by blunt-ended double-stranded (ds)RNAs carrying a 5' triphosphate (ppp) moiety. These features found in many pathogenic RNAs are absent in cellular RNAs due to post-transcriptional modifications of RNA ends. Although RIG-I is structurally well characterized, the mechanistic basis for RIG-I's remarkable ability to discriminate between cellular and pathogenic RNAs is not completely understood. We show that RIG-I's selectivity for blunt-ended 5'-ppp dsRNAs is ≈3000 times higher than non-blunt ended dsRNAs commonly found in cellular RNAs. Discrimination occurs at multiple stages and signaling RNAs have high affinity and ATPase turnover rate and thus a high katpase/Kd. We show that RIG-I uses its autoinhibitory CARD2-Hel2i (second CARD-helicase insertion domain) interface as a barrier to select against non-blunt ended dsRNAs. Accordingly, deletion of CARDs or point mutations in the CARD2-Hel2i interface decreases the selectivity from ≈3000 to 150 and 750, respectively. We propose that the CARD2-Hel2i interface is a 'gate' that prevents cellular RNAs from generating productive complexes that can signal. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  14. Eigenfunction expansions and scattering theory in rigged Hilbert spaces

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Cubillo, F [Dpt. de Analisis Matematico, Universidad de Valladolid. Facultad de Ciencias, 47011 Valladolid (Spain)], E-mail: fgcubill@am.uva.es

    2008-08-15

    The work reviews some mathematical aspects of spectral properties, eigenfunction expansions and scattering theory in rigged Hilbert spaces, laying emphasis on Lippmann-Schwinger equations and Schroedinger operators.

  15. Vibration features of an 180 kW maglev circulator test rig

    International Nuclear Information System (INIS)

    Su Jiageng; Li Hongwei; Shi Qian; Sha Honglei; Yu Suyuan

    2015-01-01

    The helium circulator is the key equipment to drive the helium gas flowing in the primary loop for energy exchange in HTGR. Active magnetic bearings (AMB) have been considered as an alternative to replace traditional mechanical bearings in the helium circulator. Such contactless bearings do not have frictional wear and can be used to suppress vibration in rotor-dynamic applications. It is necessary to study the vibration characteristics of the maglev helium circulator to guarantee the reactor safety. Therefore, a maglev circulator test rig was built. The power of the circulator is 180 kW and the maximum speed is 17000 rpm. For the time being, the test atmosphere is air. In this paper the test rig was introduced. Vibration test work of the maglev circulator was also carried out. The measuring points were arranged at the seat because the seat vibration level is important to evaluate the machine noise. The measuring points were also arranged at the base of the circulator housing to better study the vibration characteristics. The vibrations were measured by the LC-8024 multichannel machinery diagnoses system. At each measuring point the vibrations were detected in three directions (X, Y and Z) with the vibration acceleration sensors. The test speeds varied from 1000 rpm to 17000 rpm with an increase of 1000 rpm each time. The vibration values of the seat are from 89.5 dB at 1000 rpm to 113.3 dB at 17000 rpm. The test results showed that the maglev circulator exhibits good vibration properties. This work will offer important theoretical base and engineering experience to explore the high-speed helium circulator in HTGR. (author)

  16. Research on control system of truck-mounted rig for coalbed methane

    Directory of Open Access Journals (Sweden)

    Wang Hejian

    2018-01-01

    Full Text Available The coal-bed methane (CBM as a kind energy is clean and efficient, also it can become a security risk in mining process if it could not get out of the coal seam. In view of the current large-scale exploitation of coal-bed methane resources, the development of drilling rig for CBM drilling is needed. The parameters and structures were introduced in the paper. The rig uses a highly integrated approach that integrates the required functions on the chassis of the vehicle to meet the needs of rapid installation and transportation. Drilling control system uses hydraulic control and electro-hydraulic control dual control mode, can achieve short-range and remote control operations. The control system include security circuits and electric control system. Through the field trial, it is shown that the rig can meet the construction of the majority of coalbed methane drilling in the country and the performance is stable and the operation is simple.

  17. Quorum sensing in the plant pathogen Erwinia carotovora subsp. carotovora: the role of expR(Ecc).

    Science.gov (United States)

    Andersson, R A; Eriksson, A R; Heikinheimo, R; Mäe, A; Pirhonen, M; Kõiv, V; Hyytiäinen, H; Tuikkala, A; Palva, E T

    2000-04-01

    The production of the main virulence determinants of the plant pathogen Erwinia carotovora subsp. carotovora, the extracellular cell wall-degrading enzymes, is partly controlled by the diffusible signal molecule N-(3-oxohexanoyl)-L-homoserine lactone (OHHL). OHHL is synthesized by the product of the expI/carI gene. Linked to expI we found a gene encoding a putative transcriptional regulator of the LuxR-family. This gene, expR(Ecc), is transcribed convergently to the expI gene and the two open reading frames are partially overlapping. The ExpR(Ecc) protein showed extensive amino acid sequence similarity to the repressor EsaR from Pantoea stewartii subsp. stewartii (formerly Erwinia stewartii subsp. stewartii) and to the ExpR(Ech) protein of Erwinia chrysanthemi. Inactivation of the E. carotovora subsp. carotovora expR(Ecc) gene caused no decrease in virulence or production of virulence determinants in vitro. In contrast, there was a slight increase in the maceration capacity of the mutant strain. The effects of ExpR(Ecc) were probably mediated by changes in OHHL levels. Inactivation of expR(Ecc) resulted in increased OHHL levels during early logarithmic growth. In addition, overexpression of expR(Ecc) caused a clear decrease in the production of virulence determinants and part of this effect was likely to be caused by OHHL binding to ExpR(Ecc). ExpR(Ecc) did not appear to exhibit transcriptional regulation of expI, but the effect on OHHL was apparently due to other mechanisms.

  18. Exact solutions for nonlinear evolution equations using Exp-function method

    International Nuclear Information System (INIS)

    Bekir, Ahmet; Boz, Ahmet

    2008-01-01

    In this Letter, the Exp-function method is used to construct solitary and soliton solutions of nonlinear evolution equations. The Klein-Gordon, Burger-Fisher and Sharma-Tasso-Olver equations are chosen to illustrate the effectiveness of the method. The method is straightforward and concise, and its applications are promising. The Exp-function method presents a wider applicability for handling nonlinear wave equations

  19. Development of a test rig and its application for validation and reliability testing of safety-critical software

    Energy Technology Data Exchange (ETDEWEB)

    Thai, N D; McDonald, A M [Atomic Energy of Canada Ltd., Mississauga, ON (Canada)

    1996-12-31

    This paper describes a versatile test rig developed by AECL for functional testing of safety-critical software used in the process trip computers of the Wolsong CANDU stations. The description covers the hardware and software aspects of the test rig, the test language and its interpreter, and other major testing software utilities such as the test oracle, sampler and profiler. The paper also discusses the application of the rig in the final stages of testing of the process trip computer software, namely validation and reliability tests. It shows how random test cases are generated, test scripts prepared and automatically run on the test rig. The versatility of the rig is further demonstrated in other types of testing such as sub-system tests, verification of the test oracle, testing of newly-developed test script, self-test and calibration. (author). 5 tabs., 10 figs.

  20. Development of a test rig and its application for validation and reliability testing of safety-critical software

    International Nuclear Information System (INIS)

    Thai, N.D.; McDonald, A.M.

    1995-01-01

    This paper describes a versatile test rig developed by AECL for functional testing of safety-critical software used in the process trip computers of the Wolsong CANDU stations. The description covers the hardware and software aspects of the test rig, the test language and its interpreter, and other major testing software utilities such as the test oracle, sampler and profiler. The paper also discusses the application of the rig in the final stages of testing of the process trip computer software, namely validation and reliability tests. It shows how random test cases are generated, test scripts prepared and automatically run on the test rig. The versatility of the rig is further demonstrated in other types of testing such as sub-system tests, verification of the test oracle, testing of newly-developed test script, self-test and calibration. (author). 5 tabs., 10 figs

  1. Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

    Science.gov (United States)

    Chiang, Jessica J; Sparrer, Konstantin M J; van Gent, Michiel; Lässig, Charlotte; Huang, Teng; Osterrieder, Nikolaus; Hopfner, Karl-Peter; Gack, Michaela U

    2018-01-01

    The sensor RIG-I detects double-stranded RNA derived from RNA viruses. Although RIG-I is also known to have a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG-I during infection with a DNA virus are largely unknown. Using next-generation RNA sequencing (RNAseq), we found that host-derived RNAs, most prominently 5S ribosomal RNA pseudogene 141 (RNA5SP141), bound to RIG-I during infection with herpes simplex virus 1 (HSV-1). Infection with HSV-1 induced relocalization of RNA5SP141 from the nucleus to the cytoplasm, and virus-induced shutoff of host protein synthesis downregulated the abundance of RNA5SP141-interacting proteins, which allowed RNA5SP141 to bind RIG-I and induce the expression of type I interferons. Silencing of RNA5SP141 strongly dampened the antiviral response to HSV-1 and the related virus Epstein-Barr virus (EBV), as well as influenza A virus (IAV). Our findings reveal that antiviral immunity can be triggered by host RNAs that are unshielded following depletion of their respective binding proteins by the virus.

  2. The Effect of Lactate, Albumin, C-reactive Protein, PaO2/FiO2 and Glucose Levels of Trauma Patients at the Time of Administration to Intensive Care

    Directory of Open Access Journals (Sweden)

    Eren Yılmaz

    2014-12-01

    Full Text Available Objective: Blood analyses are preferred in the observation of cases requiring intensive care unit (ICU following a trauma. The purpose of this study was to examine the relationship of albumin, C-reactive protein (CRP, PaO2/FiO2 and glucose levels of trauma patients at time of admission with mortality. Material and Method: The patients who were admitted into ICU following a trauma between the years of 2010 and 2012 were retrospectively evaluated. 200 trauma cases were included in the study. Their demographic data, APACHE II scores, Glasgow Coma Scales (GCS, and arterial blood gas in the lactate and PaO2/FiO2 ratio, CRP, glucose and albumin levels in the first collected arterial blood gas, as well as, the presence of thoracic, cardiac, renal, abdominal and head trauma, length of ICU stay and mortality were recorded. Results: Of the patients included in the study 84% were male, with an average age of 38.3 and an average APACHE II score of 16.6. 64% suffered from head trauma and the average GCS was calculated to be 11.2. The patients were observed in the ICU for an average of 18.7 days and the rate of mortality was 33.5%. GCS, PaO2/FiO2, age and elevated lactate levels increased mortality as independent risk factors. Conclusion: It has been concluded that parameters like age and the first GCS, lactate, glucose, albumin and PaO2/FiO2 at time of acceptance into the ICU were found to be related with mortality.

  3. Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5.

    Science.gov (United States)

    Louber, Jade; Brunel, Joanna; Uchikawa, Emiko; Cusack, Stephen; Gerlier, Denis

    2015-07-28

    The cytoplasmic RIG-like receptors are responsible for the early detection of viruses and other intracellular microbes by activating the innate immune response mediated by type I interferons (IFNs). RIG-I and MDA5 detect virus-specific RNA motifs with short 5'-tri/diphosphorylated, blunt-end double-stranded RNA (dsRNA) and >0.5-2 kb long dsRNA as canonical agonists, respectively. However, in vitro, they can bind to many RNA species, while in cells there is an activation threshold. As SF2 helicase/ATPase family members, ATP hydrolysis is dependent on co-operative RNA and ATP binding. Whereas simultaneous ATP and cognate RNA binding is sufficient to activate RIG-I by releasing autoinhibition of the signaling domains, the physiological role of the ATPase activity of RIG-I and MDA5 remains controversial. A cross-analysis of a rationally designed panel of RNA binding and ATPase mutants and truncated receptors, using type I IFN promoter activation as readout, allows us to refine our understanding of the structure-function relationships of RIG-I and MDA5. RNA activation of RIG-I depends on multiple critical RNA binding sites in its helicase domain as confirmed by functional evidence using novel mutations. We found that RIG-I or MDA5 mutants with low ATP hydrolysis activity exhibit constitutive activity but this was fully reverted when associated with mutations preventing RNA binding to the helicase domain. We propose that the turnover kinetics of the ATPase domain enables the discrimination of self/non-self RNA by both RIG-I and MDA5. Non-cognate, possibly self, RNA binding would lead to fast ATP turnover and RNA disassociation and thus insufficient time for the caspase activation and recruitment domains (CARDs) to promote downstream signaling, whereas tighter cognate RNA binding provides a longer time window for downstream events to be engaged. The exquisite fine-tuning of RIG-I and MDA5 RNA-dependent ATPase activity coupled to CARD release allows a robust IFN response

  4. Resonances, scattering theory and rigged Hilbert spaces

    International Nuclear Information System (INIS)

    Parravicini, G.; Gorini, V.; Sudarshan, E.C.G.

    1979-01-01

    The problem of decaying states and resonances is examined within the framework of scattering theory in a rigged Hilbert space formalism. The stationary free, in, and out eigenvectors of formal scattering theory, which have a rigorous setting in rigged Hilbert space, are considered to be analytic functions of the energy eigenvalue. The value of these analytic functions at any point of regularity, real or complex, is an eigenvector with eigenvalue equal to the position of the point. The poles of the eigenvector families give origin to other eigenvectors of the Hamiltonian; the singularities of the out eigenvector family are the same as those of the continued S matrix, so that resonances are seen as eigenvectors of the Hamiltonian with eigenvalue equal to their location in the complex energy plane. Cauchy theorem then provides for expansions in terms of complete sets of eigenvectors with complex eigenvalues of the Hamiltonian. Applying such expansions to the survival amplitude of a decaying state, one finds that resonances give discrete contributions with purely exponential time behavior; the background is of course present, but explicitly separated. The resolvent of the Hamiltonian, restricted to the nuclear space appearing in the rigged Hilbert space, can be continued across the absolutely continuous spectrum; the singularities of the continuation are the same as those of the out eigenvectors. The free, in and out eigenvectors with complex eigenvalues and those corresponding to resonances can be approximated by physical vectors in the Hilbert space, as plane waves can. The need for having some further physical information in addition to the specification of the total Hamiltonian is apparent in the proposed framework. The formalism is applied to the Lee-Friedrichs model. 48 references

  5. Fios ortodônticos: conhecer para otimizar a aplicação clínica Orthodontic wires: knowledge to optimize clinical application

    Directory of Open Access Journals (Sweden)

    Cátia Cardoso Abdo Quintão

    2009-12-01

    Full Text Available A grande variedade de fios ortodônticos presente no mercado pode gerar dúvidas quanto à melhor escolha para situações clínicas. Assim, o conhecimento das propriedades mecânicas dos mesmos facilita a escolha para aplicação do movimento ortodôntico na dependência da fase em que o tratamento se encontra. A evolução da tecnologia de manufatura dos fios e a elaboração de novas técnicas ortodônticas geraram a busca por uma melhor qualidade das ligas, a fim de torná-los biologicamente mais efetivos no que diz respeito aos dentes e tecidos de suporte. O presente artigo resume as principais características dos fios utilizados em Ortodontia, em relação ao histórico, propriedades mecânicas e aplicação clínica, de acordo com fases específicas de tratamento.The huge variety of orthodontic wires brands available in market might generate confusion as regard to the best choice for clinical application. Therefore mechanical properties knowledge about wires would help the professional to apply the best orthodontic technique depending on the treatment phase. The wires manufacturing evolution and the new orthodontic techniques proposed guided the market into the search for better quality alloys, in order to make them biologically more effective to teeth and support tissues. This paper aims to summarize some main characteristics of orthodontic wires related to their history, mechanical properties and clinical application as regard to individual phase of treatment.

  6. Injury Rates on New and Old Technology Oil and Gas Rigs Operated by the Largest United States Onshore Drilling Contractor

    Science.gov (United States)

    Blackley, David J.; Retzer, Kyla D.; Hubler, Warren G.; Hill, Ryan D.; Laney, A. Scott

    2015-01-01

    Background Occupational fatality rates among oil and gas extraction industry and specifically among drilling contractor workers are high compared to the U.S. all-industry average. There is scant literature focused on non-fatal injuries among drilling contractors, some of which have introduced engineering controls to improve rig efficiency and reduce injury risk. Methods We compared injury rates on new and old technology rigs operated by the largest U.S. drilling contractor during 2003–2012, stratifying by job type and grouping outcomes by injury severity and body part affected. Results Six hundred seventy-one injuries were recorded over 77.4 million person-hours. The rate on new rigs was 66% of that on old rigs. Roughnecks had lower injury rates on new rigs, largely through reduced limb injury rates. New rigs had lower rates in each non-fatal injury severity category. Conclusions For this company, new technology rigs appear to provide a safer environment for roughnecks. Future studies could include data from additional companies. PMID:25164118

  7. Injury rates on new and old technology oil and gas rigs operated by the largest United States onshore drilling contractor.

    Science.gov (United States)

    Blackley, David J; Retzer, Kyla D; Hubler, Warren G; Hill, Ryan D; Laney, A Scott

    2014-10-01

    Occupational fatality rates among oil and gas extraction industry and specifically among drilling contractor workers are high compared to the U.S. all-industry average. There is scant literature focused on non-fatal injuries among drilling contractors, some of which have introduced engineering controls to improve rig efficiency and reduce injury risk. We compared injury rates on new and old technology rigs operated by the largest U.S. drilling contractor during 2003-2012, stratifying by job type and grouping outcomes by injury severity and body part affected. Six hundred seventy-one injuries were recorded over 77.4 million person-hours. The rate on new rigs was 66% of that on old rigs. Roughnecks had lower injury rates on new rigs, largely through reduced limb injury rates. New rigs had lower rates in each non-fatal injury severity category. For this company, new technology rigs appear to provide a safer environment for roughnecks. Future studies could include data from additional companies. © 2014 Wiley Periodicals, Inc.

  8. Fricção em braquetes gerada por fios de aço inoxidável, superelásticos com IonGuard e sem IonGuard Friction force on brackets generated by stainless steel wire and superelastic wires with and without IonGuard

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Campos Braga

    2011-08-01

    Full Text Available OBJETIVO: o objetivo deste estudo foi verificar a fricção no braquete (Roth, Composite, 10.17.005, 3,2mm, largura 0,022" x 0,030", Torque -2° e angulação +13°, Morelli®, Brasil, utilizando fios ortodônticos retangulares de 0,019" x 0,025" de aço inoxidável (Morelli®, Brasil e de níquel-titânio superelásticos Bioforce com IonGuard e sem IonGuard (Bioforce, GAC®, EUA. MÉTODOS: foram utilizados 24 conjuntos braquetes/segmento de fio, divididos em 3 grupos de acordo com o fio. Cada conjunto braquete/segmento de fio foi testado 3 vezes e obtida uma média. Os ensaios foram realizados em máquina universal de ensaios EMIC DL2000®. Os dados foram submetidos à Análise de Variância com significância de 95%. RESULTADOS: o fio retangular Bioforce com IonGuard apresentou fricção significativamente menor que o Bioforce sem IonGuard, porém sem diferença do fio de aço inoxidável. Entretanto, o coeficiente de variação dos fios Bioforce com e sem IonGuard foi menor que o do fio de aço inoxidável. CONCLUSÃO: os fios retangulares de 0,019" x 0,025" Bioforce com IonGuard apresentam menor fricção que o fio Bioforce sem IonGuard, sem diferença para o fio de aço inoxidável.OBJECTIVE: The aim of this study was to evaluate the friction forces on brackets (Roth, Composite, 10.17.005, 3.2 mm, width 0.022" x 0.030 ", Torque -2° and angulation +13°, Morelli®, Brazil, with stainless steel orthodontic rectangular wire (Morelli®, Brazil and nickel titanium superelastic Bioforce wires with and without IonGuard (Bioforce, GAC®, USA. MATERIAL AND METHODS: Twenty-four brackets/wire segment combinations were used, distributed into three groups according to the orthodontic wire. Each bracket/wire segment combination was tested three times. The tests were performed in a universal testing machine Emic DL2000®. The data was submitted to ANOVA one way followed by Tukey's post hoc test (p<0.05. RESULTS: The rectangular orthodontic Bioforce wire

  9. Exp2 polymorphisms associated with variation for fiber quality properties in cotton (Gossypium spp.

    Directory of Open Access Journals (Sweden)

    Daohua He

    2014-10-01

    Full Text Available Plant expansins are a group of extracellular proteins thought to affect the quality of cotton fibers. Previous expression profile analysis revealed that six Expansin A genes are present in cotton, of which two (GhExp1 and GhExp2 produce transcripts that are specific to the developing cotton fiber. To identify the phenotypic function of Exp2, and to determine whether nucleotide variation among alleles of Exp2 affects fiber quality, candidate gene association mapping was conducted. Gene-specific primers were designed to amplify the Exp2 gene. By amplicon sequencing, the nucleotide diversity of Exp2 was investigated across 92 accessions (including 7 Gossypium arboreum, 74 Gossypium hirsutum, and 11 Gossypium barbadense accessions with different fiber qualities. Twenty-six SNPs and seven InDels including 14 from the coding region of Exp2 were detected, forming twelve distinct haplotypes in the cotton collection. Among the 14 SNPs in the coding region, five were missense mutations and nine were synonymous nucleotide changes. The average SNP/InDel per nucleotide ratio was 2.61% (one SNP per 39 bp, with 1.81 and 3.87% occurring in coding and non-coding regions, respectively. Nucleotide and haplotype diversity across the entire Exp2 region was 0.00603 (π and 0.844, respectively, and diversity in non-coding regions was higher than that in coding regions. For linkage disequilibrium (LD, the mean r2 value for all polymorphism loci pairs was 0.48, and LD did not decay over 748 bp. Based on 132 simple sequence repeat (SSR loci evenly covering 26 chromosomes, the population structure was estimated, and the accessions were divided into seven groups that agreed well with their genomic origin and evolutionary history. A general linear model was used to calculate the Exp2-wide diversity–trait associations of 5 fiber quality traits, considering population structure (Q. Four SNPs in Exp2 were associated with at least one of the fiber quality traits, but not with

  10. States in 118Sn from 117Sn(d,p) 118Sn at 12 MeV

    International Nuclear Information System (INIS)

    Frota-Pessoa, E.

    1983-01-01

    118 Sn energy levels up to = 5.2 MeV excitation energy are studied in the reaction 117 Sn (d,p) 118 Sn. Deuterons had a bombarding energy of 12 MeV. The protons were analized by a magnetic spectrograph. The detector was nuclear emulsion and the resolution in energy about 10 KeV. The distorted-wave analysis was used to determine l values and spectroscopic strengths. Centers of gravity and the sums of reduced spectroscopic factors are presented for the levels when it was possible to determine the S' value. 66 levels of excitation energy were found which did not appear in previous 117 Sn (d,p) reactions. 40 levels were not found previously in any reaction giving 118 Sn. The results are compared with the known ones. (Author) [pt

  11. The Design and Manufacturing Report of Plug Type Non-Instrumented Rig for Irradiation Test in HANARO OR Hole

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dae Ho; Bang, Je Geon; Lim, Ik Sung; Kim, Sun Ki; Yang, Yong Sik; Song, Kun Woo

    2008-09-15

    This project is developed the plug type non-instrumented irradiation test rig of the advanced nuclear fuel in HANARO for pursuit advanced performance in High Performance Fuel Technology Development as a part Nuclear Mid and Long-term R and D Program. This irradiation rig was confirmed the integrity and HANARO core compatibility by the optimum design and the thermal hydraulic out-pile test in FIVPET. The characteristic of plug type non-instrument rig is to possible irradiation test of variable in-pile condition and reduced the wastes for reusable as function. This plug type non-instrumented rig was satisfied the quality assurance requirements and written out the end of manufacturing report. This plug type non-instrumented rig is adopt to the irradiation test for nuclear fuel irradiation test in HANARO OR hole.

  12. The influence of chemicals on water quality in a high pressure separation rig

    Energy Technology Data Exchange (ETDEWEB)

    Johnsen, Einar E.; Hemmingsen, Paal V.; Mediaas, Heidi; Svarstad, May Britt E.; Westvik, Arild

    2006-03-15

    In the research laboratory of Statoil at Rotvoll, Trondheim, a high pressure experimental rig used for separation and foaming studies has been developed. There have been several studies to ensure that the high pressure separation rig produces reliable and consistent results with regard to the water-in-oil and oil-in-water contents. The results are consistent with available field data and, just as important, consistent when changing variables like temperature, pressure drop and water cut. The results are also consistent when changing hydrodynamic variables like flow velocity and mixing point (using different choke valves) and when using oil with and without gas saturation. At equal experimental conditions, the high pressure separation rig is able to differentiate between separation characteristics of oil and water from different fields and from different wells at the same field. The high pressure separation and foam rig can be used from -10 deg C to 175 deg C and at pressures up to 200 bar. Crude oil and water are studied under relevant process conditions with respect to temperature, pressure, shear, water cut and separation time. In the present work the influence of chemicals on the oil and water quality has been studied. Chemicals have been mixed into the oil and/or water beforehand or added in situ (on-stream; simulated well stream). The amount of oil in the water after a given residence time in the separation cell has been measured. The results from the high pressure rig show that some demulsifiers, with their primary purpose of giving less water in oil, also have influence on the water quality. Improvement of water quality has been observed as well as no effect or aggravation. The experimental results have been compared to results from bottle tests at the field. The results from the bottle tests and from the laboratory are not corresponding, and only a full-scale field test can tell which of them are the correct results, if any. (Experience from corresponding

  13. Mach 0.3 Burner Rig Facility at the NASA Glenn Materials Research Laboratory

    Science.gov (United States)

    Fox, Dennis S.; Miller, Robert A.; Zhu, Dongming; Perez, Michael; Cuy, Michael D.; Robinson, R. Craig

    2011-01-01

    This Technical Memorandum presents the current capabilities of the state-of-the-art Mach 0.3 Burner Rig Facility. It is used for materials research including oxidation, corrosion, erosion and impact. Consisting of seven computer controlled jet-fueled combustors in individual test cells, these relatively small rigs burn just 2 to 3 gal of jet fuel per hour. The rigs are used as an efficient means of subjecting potential aircraft engine/airframe advanced materials to the high temperatures, high velocities and thermal cycling closely approximating actual operating environments. Materials of various geometries and compositions can be evaluated at temperatures from 700 to 2400 F. Tests are conducted not only on bare superalloys and ceramics, but also to study the behavior and durability of protective coatings applied to those materials.

  14. 33 CFR 118.90 - Bridges crossing channel obliquely.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Bridges crossing channel obliquely. 118.90 Section 118.90 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.90 Bridges crossing channel obliquely. Bridges...

  15. 7 CFR 15.118 - Cross-examination.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Cross-examination. 15.118 Section 15.118 Agriculture Office of the Secretary of Agriculture NONDISCRIMINATION Rules of Practice and Procedure for Hearings...-examination. Cross-examination will be limited to the scope of direct examination and matters at issue in the...

  16. Test Rig for Valves of Digital Displacement Machines

    DEFF Research Database (Denmark)

    Nørgård, Christian; Christensen, Jeppe Haals; Bech, Michael Møller

    2017-01-01

    A test rig for the valves of digital displacement machines has been developed at Aalborg University. It is composed of a commercial radial piston machine, which has been modified to facilitate Digital Displacement operation for a single piston. Prototype valves have been optimized, designed and m...

  17. Viral RNA-Unprimed Rig-I Restrains Stat3 Activation in the Modulation of Regulatory T Cell/Th17 Cell Balance.

    Science.gov (United States)

    Yang, Hui; Guo, He-Zhou; Li, Xian-Yang; Lin, Jian; Zhang, Wu; Zhao, Jun-Mei; Zhang, Hong-Xin; Chen, Sai-Juan; Chen, Zhu; Zhu, Jiang

    2017-07-01

    Innate immunity activation by viral RNA-primed retinoid acid inducible gene-I (Rig-I) in CD4 + T cells antagonizes TGFβ signaling to suppress the differentiation of regulatory T cells (Tregs). However, how viral RNA-unliganded Rig-I (apo-Rig-I) modulates Treg generation remains unclear. In this article, we show that, in the absence of viral infection, Treg differentiation of Rig-I -/- CD4 + T cells was compromised, in the presence of increased generation of Th17 cells and overactivation of Stat3, a critical regulator tilting the Treg/Th17 cell balance. Mechanistically, apo-Rig-I physically associates with Stat3, thereby inhibiting Jak1's association with Stat3 while facilitating Shp2's association to inhibit p-Stat3 levels. Interestingly, inhibition of Stat3 ameliorates the Treg/Th17 imbalance and the colitis observed in Rig-I -/- mice. Collectively, these results uncover an independent functional contribution of the apo-Rig-I/Stat3 interaction in the maintenance of Treg/Th17 cell balance. Copyright © 2017 by The American Association of Immunologists, Inc.

  18. checkCIF/PLATON report Datablock: exp_2

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_2. Bond precision:.

  19. checkCIF/PLATON report Datablock: exp_3042

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_3042. Bond precision:.

  20. checkCIF/PLATON report Datablock: exp_2816

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_2816. Bond precision:.

  1. checkCIF/PLATON report Datablock: exp_3274

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_3274. Bond precision:.

  2. Functional characterizations of RIG-I to GCRV and viral/bacterial PAMPs in grass carp Ctenopharyngodon idella.

    Directory of Open Access Journals (Sweden)

    Lijun Chen

    Full Text Available BACKGROUND: RIG-I (retinoic acid inducible gene-I is one of the key cytosolic pattern recognition receptors (PRRs for detecting nucleotide pathogen associated molecular patterns (PAMPs and mediating the induction of type I interferon and inflammatory cytokines in innate immune response. Though the mechanism is well characterized in mammals, the study of the accurate function of RIG-I in teleosts is still in its infancy. METHODOLOGY/PRINCIPAL FINDINGS: To clarify the functional characterizations of RIG-I in grass carp Ctenopharyngodon idella (CiRIG-I, six representative overexpression plasmids were constructed and transfected into C. idella kidney (CIK cell lines to obtain stably expressing recombinant proteins, respectively. A virus titer test and 96-well plate staining assay showed that all constructs exhibited the antiviral activity somewhat. The quantitative real-time RT-PCR (qRT-PCR demonstrated that mRNA expressions of CiIPS-1, CiIFN-I and CiMx2 were regulated by not only virus (GCRV or viral PAMP (poly(IC challenge but also bacterial PAMPs (LPS and PGN stimulation in the steadily transfected cells. The results showed that the full-length CiRIG-I played a key role in RLR pathway. The repressor domain (RD exerted an inhibitory function of the signaling channel under all utilized challenges. Caspase activation and recruitment domains (CARDs showed a positive role in GCRV and poly(I:C challenge. Helicase motifs were crucial for the signaling pathway upon LPS and PGN stimulation. Interestingly, ΔCARDs (CARDs deleted showed positive modulation in RIG-I signal transduction. CONCLUSIONS/SIGNIFICANCE: The results provided some novel insights into RIG-I sensing with a strikingly broad regulation in teleosts, responding not only to the dsRNA virus or synthetic dsRNA but also bacterial PAMPs.

  3. 33 CFR 118.70 - Lights on swing bridges.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lights on swing bridges. 118.70 Section 118.70 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.70 Lights on swing bridges. (a) Swing span lights on through bridges. Each...

  4. 33 CFR 118.80 - Lights on bascule bridges.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lights on bascule bridges. 118.80 Section 118.80 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.80 Lights on bascule bridges. (a) Lift span lights. Each lift span of...

  5. 33 CFR 118.65 - Lights on fixed bridges.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lights on fixed bridges. 118.65 Section 118.65 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.65 Lights on fixed bridges. (a) Each fixed bridge span over a navigable...

  6. Cloning of low dose radiation induced gene RIG1 by RACE based on non-cloned cDNA library

    International Nuclear Information System (INIS)

    Luo Ying; Sui Jianli; Tie Yi; Zhang Yuanping; Zhou Pingkun; Sun Zhixian

    2001-01-01

    Objective: To obtain full-length cDNA of radiation induced new gene RIG1 based on its EST fragment. Methods: Based on non-cloned cDNA library, enhanced nested RACE PCR and biotin-avidin labelled probe for magnetic bead purification was used to obtain full-length cDNA of RIG1. Results: About 1 kb of 3' end of RIG1 gene was successfully cloned by this set of methods and cloning of RIG1 5' end is proceeding well. Conclusion: The result is consistent with the design of experiment. This set of protocol is useful for cloning of full-length gene based on EST fragment

  7. 46 CFR 118.300 - Fire pumps.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire pumps. 118.300 Section 118.300 Shipping COAST GUARD... Fire pumps. (a) A self priming, power driven fire pump must be installed on each vessel. (b) On a..., the fire pump must be capable of delivering a single hose stream from the highest hydrant, through the...

  8. A Study on the Dynamic Analysis of the Nuclear Fuel Test Rig Using 1-Way Fluid-Structure Coupled Analysis

    International Nuclear Information System (INIS)

    Yang, Tae-Ho; Hong, Jin-Tae; Ahn, Sung-Ho; Joung, Chang-Young; Heo, Sung-Ho; Jang, Seo-Yun

    2015-01-01

    1-way fluid-structure coupled analysis is used to estimate the dynamic characteristic of the fuel test rig. the motion at the bottom of the test rig is confirmed. The maximum deformation of the test rig is 0.11 mm. The structural integrity of the test rig is performed by using the comparison with the Von-mises stress of the analysis and yield stress of the material. It is evaluated that the motion at the bottom of the test rig is able to cause other structural problem. Using the 2-way fluid-structural coupled analysis, the structural integrity of the test rig will be performed in further paper. The cooling water with specific flow rate was flowed in the nuclear fuel test rig. The structural integrity of the test rig was affected by the vibration. The fluid-induced vibration test had to be performed to obtain the amplitude of the vibration on the structure. Various test systems was developed. Flow-induced vibration and pressure drop experimental tester was developed in Korea Atomic Energy Research Institute. The vibration test with high fluid flow rate was difficult by the tester. To generate the nuclear fuel test environment, coolant flow simulation system was developed. The scaled nuclear fuel test was able to be performed by the simulation system. The mock-up model of the test rig was used in the simulation system. The mock-up model in the simulation system was manufactured with scaled down full model. In this paper, the fluid induced vibration characteristic of the full model in the nuclear fuel test is studied. The hydraulic pressure on the velocity of the fluid was calculated. The static structure analysis was performed by using the pressure. The structural integrity was assessed using the results of the analysis

  9. Test Rig for Evaluating Active Turbine Blade Tip Clearance Control Concepts

    Science.gov (United States)

    Lattime, Scott B.; Steinetz, Bruce M.; Robbie, Malcolm G.

    2003-01-01

    Improved blade tip sealing in the high pressure compressor and high pressure turbine can provide dramatic improvements in specific fuel consumption, time-on-wing, compressor stall margin and engine efficiency as well as increased payload and mission range capabilities of both military and commercial gas turbine engines. The preliminary design of a mechanically actuated active clearance control (ACC) system for turbine blade tip clearance management is presented along with the design of a bench top test rig in which the system is to be evaluated. The ACC system utilizes mechanically actuated seal carrier segments and clearance measurement feedback to provide fast and precise active clearance control throughout engine operation. The purpose of this active clearance control system is to improve upon current case cooling methods. These systems have relatively slow response and do not use clearance measurement, thereby forcing cold build clearances to set the minimum clearances at extreme operating conditions (e.g., takeoff, re-burst) and not allowing cruise clearances to be minimized due to the possibility of throttle transients (e.g., step change in altitude). The active turbine blade tip clearance control system design presented herein will be evaluated to ensure that proper response and positional accuracy is achievable under simulated high-pressure turbine conditions. The test rig will simulate proper seal carrier pressure and temperature loading as well as the magnitudes and rates of blade tip clearance changes of an actual gas turbine engine. The results of these evaluations will be presented in future works.

  10. Characterization of the genetic locus responsible for the production of ABP-118, a novel bacteriocin produced by the probiotic bacterium Lactobacillus salivarius subsp. salivarius UCC118.

    Science.gov (United States)

    Flynn, Sarah; van Sinderen, Douwe; Thornton, Gerardine M; Holo, Helge; Nes, Ingolf F; Collins, J Kevin

    2002-04-01

    ABP-118, a small heat-stable bacteriocin produced by Lactobacillus salivarius subsp. salivarius UCC118, a strain isolated from the ileal-caecal region of the human gastrointestinal tract, was purified to homogeneity. Using reverse genetics, a DNA fragment specifying part of ABP-118 was identified on a 10769 bp chromosomal region. Analysis of this region revealed that ABP-118 was a Class IIb two-peptide bacteriocin composed of Abp118alpha, which exhibited the antimicrobial activity, and Abp118beta, which enhanced the antimicrobial activity. The gene conferring strain UCC118 immunity to the action of ABP-118, abpIM, was identified downstream of the abp118beta gene. Located further downstream of abp118beta, several ORFs were identified whose deduced proteins resembled those of proteins involved in bacteriocin regulation and secretion. Heterologous expression of ABP-118 was achieved in Lactobacillus plantarum, Lactococcus lactis and Bacillus cereus. In addition, the abp118 locus encoded an inducing peptide, AbpIP, which was shown to play a role in the regulation of ABP-118 production. This novel bacteriocin is, to the authors' knowledge, the first to be isolated from a known human probiotic bacterium and to be characterized at the genetic level.

  11. Mapa de energia baseado em predição para redes de sensores sem fio

    OpenAIRE

    Raquel Aparecida de Freitas Mini

    2004-01-01

    O objetivo deste trabalho é construir o mapa de energia de uma rede de sensores sem fio utilizando técnicas de predição. Em mapas de energia baseados em predição, cada nó sensor utiliza algoritmos de predição para modelar sua dissipação de energia com o objetivo de prever seu consumo de energia no futuro. Nesta situação, ao invés de enviar para o nó sorvedouro apenas sua quantidade de energia disponível, cada sensor envia também os parâmetros do modelo que descreve seu consumo de energia. O n...

  12. Symphonie « pragmatique » de l’expérience musicale.

    Directory of Open Access Journals (Sweden)

    François Debruyne

    2011-03-01

    Full Text Available User d’une métaphore musicale éculée, celle de la symphonie , pour commenter une œuvre sociologique qui a pour thème « l’expérience musicale » peut sembler accessoire pour décrire un ouvrage, dont le titre et le sous-titre originaux – Écologie sociale de l’oreille. Enquêtes sur l’expérience musicale  – disent plus précisément ce dont il est question. Néanmoins, surtitrer Symphonie « pragmatique » de l’expérience musicale permet à la fois de signifier ...

  13. The moisture proof connection of signal cables on test rig instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Joung, Chang Young; Ahn, Sung Ho; Hong, Jin Tae; Jeong, Hwang Young [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-10-15

    The rod inner pressure, centerline temperature, coolant temperature, and neutron flux resulting from the irradiation properties of nuclear fuel are an important factor for evaluating nuclear fuel properties in pile. In addition instrumentation and measurement techniques for nuclear fuel are necessary to measure the exact data. Special sensors such as a TC (thermocouple), LVDT (linear variable differential transformer) and SPND (self-powered neutron detector) are instrumented in and out of the fuel rod to measure the various irradiation characteristics of the nuclear fuel. These sensors are made up of the sensor itself and a signal cable. In the instrumentation, an MI (Mineral Insulated) cable used as the signal cable has such properties as high electrical insulation, heat resistance, and mechanical strength. However, it is difficult to handle and treat with care owing to the extremely hard composition, which is made up of weak signal wires and alumina powder in a stainless tube. The sealing of the end tip of the MI cable and extension cable is very important in terms of the insulation resistance to seal the insulator inside the MI cable tube from moisture. To maintain the insulation of sensors and signal cables, the insulation resistance must be checked in accordance with each process throughout the instrumentation and fabrication period. To safely mount the signal cables drawn from a fuel test rig on the terminal block of a junction panel, the MI and extension cables should be easy to connect. Therefore, it is necessary to develop instrumentation technologies of a moisture proof connection process for a fuel test rig. This paper will provide an overview of the work done with moisture proof connection procedures to connect the MI and extension cables to extend the MI cables jointed with the sensor.

  14. Remote and Virtual Labs @ exp.at’11

    Directory of Open Access Journals (Sweden)

    Maria Teresa Restivo

    2012-03-01

    Full Text Available exp.at’11, the first event of Experiment@, a new International Conference series devoted to online experimentation, had as scope to contribute to the world capabilities in online experimentation and in particular in remote and virtual labs, fostering the collaborative work in emergent technologies.

  15. Glutathione oxidation correlates with one-lung ventilation time and PO2/FiO2 ratio during pulmonary lobectomy.

    Science.gov (United States)

    García-de-la-Asunción, José; García-Del-Olmo, Eva; Galan, Genaro; Guijarro, Ricardo; Martí, Francisco; Badenes, Rafael; Perez-Griera, Jaume; Duca, Alejandro; Delgado, Carlos; Carbonell, Jose; Belda, Javier

    2016-09-01

    During lung lobectomy, the operated lung completely collapses with simultaneous hypoxic pulmonary vasoconstriction, followed by expansion and reperfusion. Here, we investigated glutathione oxidation and lipoperoxidation in patients undergoing lung lobectomy, during one-lung ventilation (OLV) and after resuming two-lung ventilation (TLV), and examined the relationship with OLV duration. We performed a single-centre, observational, prospective study in 32 patients undergoing lung lobectomy. Blood samples were collected at five time-points: T0, pre-operatively; T1, during OLV, 5 minutes before resuming TLV; and T2, T3, and T4, respectively, 5, 60, and 180 minutes after resuming TLV. Samples were tested for reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione redox potential, and malondialdehyde (MDA). GSSG and MDA blood levels increased at T1, and increased further at T2. OLV duration directly correlated with marker levels at T1 and T2. Blood levels of GSH and glutathione redox potential decreased at T1-T3. GSSG, oxidized glutathione/total glutathione ratio, and MDA levels were inversely correlated with arterial blood PO2/FiO2 at T1 and T2. During lung lobectomy and OLV, glutathione oxidation, and lipoperoxidation marker blood levels increase, with further increases after resuming TLV. Oxidative stress degree was directly correlated with OLV duration, and inversely correlated with arterial blood PO2/FiO2.

  16. Dynamic Investigation Test-rig on hAptics (DITA)

    International Nuclear Information System (INIS)

    Cannella, F; Olivieri, E; Caldwell, D G; Scalise, L; Memeo, M

    2013-01-01

    Research on tactile sensitivity has been conducted since the last century and many devices have been proposed to study in detail this sense through experimental tests. The sense of touch is essential in every-day life of human beings, but it can also play a fundamental role for the assessment of some neurological disabilities and pathologies. In fact, the level of tactile perception can provide information on the health state of the nervous system. In this paper, authors propose the design and development of a novel test apparatus, named DITA (Dynamic Investigation Test-rig on hAptics), aiming to provide the measurement of the tactile sensitivity trough the determination of the Just Noticeable Difference (JND) curve of a subject. The paper reports the solution adopted for the system design and the results obtained on the set of experiments carried out on volunteers

  17. expVIP: a Customizable RNA-seq Data Analysis and Visualization Platform.

    Science.gov (United States)

    Borrill, Philippa; Ramirez-Gonzalez, Ricardo; Uauy, Cristobal

    2016-04-01

    The majority of transcriptome sequencing (RNA-seq) expression studies in plants remain underutilized and inaccessible due to the use of disparate transcriptome references and the lack of skills and resources to analyze and visualize these data. We have developed expVIP, an expression visualization and integration platform, which allows easy analysis of RNA-seq data combined with an intuitive and interactive interface. Users can analyze public and user-specified data sets with minimal bioinformatics knowledge using the expVIP virtual machine. This generates a custom Web browser to visualize, sort, and filter the RNA-seq data and provides outputs for differential gene expression analysis. We demonstrate expVIP's suitability for polyploid crops and evaluate its performance across a range of biologically relevant scenarios. To exemplify its use in crop research, we developed a flexible wheat (Triticum aestivum) expression browser (www.wheat-expression.com) that can be expanded with user-generated data in a local virtual machine environment. The open-access expVIP platform will facilitate the analysis of gene expression data from a wide variety of species by enabling the easy integration, visualization, and comparison of RNA-seq data across experiments. © 2016 American Society of Plant Biologists. All Rights Reserved.

  18. Collisions damage assessment of ships and jack-up rigs

    DEFF Research Database (Denmark)

    Zhang, Shengming; Pedersen, P. Terndrup; Ocakli, Hasan

    2015-01-01

    Ship collision with offshore installations is one of the key concerns in design and assess of platforms performance and safety. This paper presents an analysis on collision energy and structural damage in ship and offshore platform collisions for various collision scenarios. The platform or rig...

  19. Application of the Exp-function method to the equal-width wave equation

    International Nuclear Information System (INIS)

    Biazar, J; Ayati, Z

    2008-01-01

    In this paper, the Exp-function method is used to find an exact solution of the equal-width wave (EW) equation. The method is straightforward and concise, and its applications are promising. It is shown that the Exp-function method, with the help of symbolic computation, provides a very effective and powerful mathematical tool for solving the EW equation.

  20. Fractional Complex Transform and exp-Function Methods for Fractional Differential Equations

    Directory of Open Access Journals (Sweden)

    Ahmet Bekir

    2013-01-01

    Full Text Available The exp-function method is presented for finding the exact solutions of nonlinear fractional equations. New solutions are constructed in fractional complex transform to convert fractional differential equations into ordinary differential equations. The fractional derivatives are described in Jumarie's modified Riemann-Liouville sense. We apply the exp-function method to both the nonlinear time and space fractional differential equations. As a result, some new exact solutions for them are successfully established.

  1. Test rig overview for validation and reliability testing of shutdown system software

    International Nuclear Information System (INIS)

    Zhao, M.; McDonald, A.; Dick, P.

    2007-01-01

    The test rig for Validation and Reliability Testing of shutdown system software has been upgraded from the AECL Windows-based test rig previously used for CANDU6 stations. It includes a Virtual Trip Computer, which is a software simulation of the functional specification of the trip computer, and a real-time trip computer simulator in a separate chassis, which is used during the preparation of trip computer test cases before the actual trip computers are available. This allows preparation work for Validation and Reliability Testing to be performed in advance of delivery of actual trip computers to maintain a project schedule. (author)

  2. Performance Analysis of Retrofitted Tribo-Corrosion Test Rig for Monitoring In Situ Oil Conditions

    Directory of Open Access Journals (Sweden)

    Arpith Siddaiah

    2017-09-01

    Full Text Available Oils and lubricants, once extracted after use from a mechanical system, can hardly be reused, and should be refurbished or replaced in most applications. New methods of in situ oil and lubricant efficiency monitoring systems have been introduced for a wide variety of mechanical systems, such as automobiles, aerospace aircrafts, ships, offshore wind turbines, and deep sea oil drilling rigs. These methods utilize electronic sensors to monitor the “byproduct effects” in a mechanical system that are not indicative of the actual remaining lifecycle and reliability of the oils. A reliable oil monitoring system should be able to monitor the wear rate and the corrosion rate of the tribo-pairs due to the inclusion of contaminants. The current study addresses this technological gap, and presents a novel design of a tribo-corrosion test rig for oils used in a dynamic system. A pin-on-disk tribometer test rig retrofitted with a three electrode-potentiostat corrosion monitoring system was used to analyze the corrosion and wear rate of a steel tribo-pair in industrial grade transmission oil. The effectiveness of the retrofitted test rig was analyzed by introducing various concentrations of contaminants in an oil medium that usually leads to a corrosive working environment. The results indicate that the retrofitted test rig can effectively monitor the in situ tribological performance of the oil in a controlled dynamic corrosive environment. It is a useful method to understand the wear–corrosion synergies for further experimental work, and to develop accurate predictive lifecycle assessment and prognostic models. The application of this system is expected to have economic benefits and help reduce the ecological oil waste footprint.

  3. Performance Analysis of Retrofitted Tribo-Corrosion Test Rig for Monitoring In Situ Oil Conditions.

    Science.gov (United States)

    Siddaiah, Arpith; Khan, Zulfiqar Ahmad; Ramachandran, Rahul; Menezes, Pradeep L

    2017-09-28

    Oils and lubricants, once extracted after use from a mechanical system, can hardly be reused, and should be refurbished or replaced in most applications. New methods of in situ oil and lubricant efficiency monitoring systems have been introduced for a wide variety of mechanical systems, such as automobiles, aerospace aircrafts, ships, offshore wind turbines, and deep sea oil drilling rigs. These methods utilize electronic sensors to monitor the "byproduct effects" in a mechanical system that are not indicative of the actual remaining lifecycle and reliability of the oils. A reliable oil monitoring system should be able to monitor the wear rate and the corrosion rate of the tribo-pairs due to the inclusion of contaminants. The current study addresses this technological gap, and presents a novel design of a tribo-corrosion test rig for oils used in a dynamic system. A pin-on-disk tribometer test rig retrofitted with a three electrode-potentiostat corrosion monitoring system was used to analyze the corrosion and wear rate of a steel tribo-pair in industrial grade transmission oil. The effectiveness of the retrofitted test rig was analyzed by introducing various concentrations of contaminants in an oil medium that usually leads to a corrosive working environment. The results indicate that the retrofitted test rig can effectively monitor the in situ tribological performance of the oil in a controlled dynamic corrosive environment. It is a useful method to understand the wear-corrosion synergies for further experimental work, and to develop accurate predictive lifecycle assessment and prognostic models. The application of this system is expected to have economic benefits and help reduce the ecological oil waste footprint.

  4. 9 CFR 118.4 - Seizure and condemnation.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Seizure and condemnation. 118.4... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS DETENTION; SEIZURE AND CONDEMNATION § 118.4 Seizure and condemnation. Any biological product which is prepared, sold, bartered...

  5. 78 FR 70326 - Rigging Equipment for Material Handling; Extension of the Office of Management and Budget's (OMB...

    Science.gov (United States)

    2013-11-25

    ...] Rigging Equipment for Material Handling; Extension of the Office of Management and Budget's (OMB) Approval... on Rigging Equipment for Material Handling (29 CFR 1926.251). These paragraphs require affixing... automated or other technological information collection and transmission techniques. III. Proposed Actions...

  6. Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

    Science.gov (United States)

    Luthra, Priya; Ramanan, Parameshwaran; Mire, Chad E; Weisend, Carla; Tsuda, Yoshimi; Yen, Benjamin; Liu, Gai; Leung, Daisy W; Geisbert, Thomas W; Ebihara, Hideki; Amarasinghe, Gaya K; Basler, Christopher F

    2013-07-17

    The cytoplasmic pattern recognition receptor RIG-I is activated by viral RNA and induces type I IFN responses to control viral replication. The cellular dsRNA binding protein PACT can also activate RIG-I. To counteract innate antiviral responses, some viruses, including Ebola virus (EBOV), encode proteins that antagonize RIG-I signaling. Here, we show that EBOV VP35 inhibits PACT-induced RIG-I ATPase activity in a dose-dependent manner. The interaction of PACT with RIG-I is disrupted by wild-type VP35, but not by VP35 mutants that are unable to bind PACT. In addition, PACT-VP35 interaction impairs the association between VP35 and the viral polymerase, thereby diminishing viral RNA synthesis and modulating EBOV replication. PACT-deficient cells are defective in IFN induction and are insensitive to VP35 function. These data support a model in which the VP35-PACT interaction is mutually antagonistic and plays a fundamental role in determining the outcome of EBOV infection. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Fios que Tecem o Tempo Escolar: do ritmo padrão à simultaneidade

    Directory of Open Access Journals (Sweden)

    Ana Sueli Teixeira de Pinho

    2017-09-01

    Full Text Available Este texto tem por objetivo tecer os fios que, de modo complexo, atam e desatam, de forma silenciosa, a constituição do tempo em duas escolas com classes multisseriadas da Ilha de Maré, problematizando a ideia de ritmo padrão e apontando a simultaneidade como possibilidade para o tempo escolar. Do ponto de vista metodológico foi adotada a narrativa (autobiográfica, e a técnica de pesquisa selecionada foi a entrevista narrativa. O estudo realizado aponta que o tempo escolar, das duas escolas pesquisadas, é convidado a reconhecer a existência e a legitimidade de outros tempos, para além do seu: o tempo da maré, o tempo do trabalho, o tempo das práticas simbólicas, o tempo livre e as temporalidades dos sujeitos.

  8. 46 CFR 171.118 - Automatic ventilators and side ports.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Automatic ventilators and side ports. 171.118 Section 171.118 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY... Bulkhead or Weather Deck § 171.118 Automatic ventilators and side ports. (a) An automatic ventilator must...

  9. 21 CFR 118.6 - Egg testing for Salmonella Enteritidis (SE).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Egg testing for Salmonella Enteritidis (SE). 118.6... (CONTINUED) FOOD FOR HUMAN CONSUMPTION PRODUCTION, STORAGE, AND TRANSPORTATION OF SHELL EGGS § 118.6 Egg... age required by § 118.4(a) is positive, you must divert eggs to treatment (defined in § 118.3) for the...

  10. RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome

    Directory of Open Access Journals (Sweden)

    Changming Lu

    2017-09-01

    Full Text Available Singleton-Merten syndrome (SMS is an autosomal dominant, multi-system innate immune disorder characterized by early and severe aortic and valvular calcification, dental and skeletal abnormalities, psoriasis, glaucoma, and other varying clinical findings. Recently we identified a specific gain-of-function mutation in IFIH1, interferon induced with helicase C domain 1, segregated with this disease. SMS disease without hallmark dental anomalies, termed atypical SMS, has recently been reported caused by variants in DDX58, DEXD/H-box helicase 58. IFIH1 and DDX58 encode retinoic acid-inducible gene I (RIG-I-like receptors family members melanoma differentiation-associated gene 5 and RIG-I, respectively. These cytosolic pattern recognition receptors function in viral RNA detection initiating an innate immune response through independent pathways that promote type I and type III interferon expression and proinflammatory cytokines. In this review, we focus on SMS as an innate immune disorder summarizing clinical features, molecular aspects of the pathogenetic pathway and discussing underlying mechanisms of the disease.

  11. Experimental and Numerical Simulation of Unbalance Response in Vertical Test Rig with Tilting-Pad Bearings

    Directory of Open Access Journals (Sweden)

    Mattias Nässelqvist

    2014-01-01

    Full Text Available In vertically oriented machines with journal bearing, there are no predefined static radial loads, such as dead weight for horizontal rotor. Most of the commercial software is designed to calculate rotordynamic and bearing properties based on machines with a horizontally oriented rotor; that is, the bearing properties are calculated at a static eccentricity. For tilting-pad bearings, there are no existing analytical expressions for bearing parameters and the bearing parameters are dependent on eccentricity and load angle. The objective of this paper is to present a simplified method to perform numerical simulations on vertical rotors including bearing parameters. Instead of recalculating the bearing parameters in each time step polynomials are used to represent the bearing parameters for present eccentricities and load angles. Numerical results are compared with results from tests performed in a test rig. The test rig consists of two guide bearings and a midspan rotor. The guide bearings are 4-pad tilting-pad bearings. Shaft displacement and strains in the bearing bracket are measured to determine the test rig’s properties. The comparison between measurements and simulated results shows small deviations in absolute displacement and load levels, which can be expected due to difficulties in calculating exact bearing parameters.

  12. 10 CFR 1.18 - Advisory Committee on Nuclear Waste.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Advisory Committee on Nuclear Waste. 1.18 Section 1.18... Panels, Boards, and Committees § 1.18 Advisory Committee on Nuclear Waste. The Advisory Committee on Nuclear Waste (ACNW) provides advice to the Commission on all aspects of nuclear waste management, as...

  13. Accelerated Bearing Life-time Test Rig Development for Low Speed Data Acquisition

    Directory of Open Access Journals (Sweden)

    Andreas Klausen

    2017-07-01

    Full Text Available Condition monitoring plays an important role in rotating machinery to ensure reliability of the equipment, and to detect fault conditions at an early stage. Although health monitoring methodologies have been thoroughly developed for rotating machinery, low-speed conditions often pose a challenge due to the low signal-to-noise ratio. To this aim, sophisticated algorithms that reduce noise and highlight the bearing faults are necessary to accurately diagnose machines undergoing this condition. In the development phase, sensor data from a healthy and damaged bearing rotating at low-speed is required to verify the performance of such algorithms. A test rig for performing accelerated life-time testing of small rolling element bearings is designed to collect necessary sensor data. Heavy loads at high-speed conditions are applied to the test bearing to wear it out fast. Sensor data is collected in intervals during the test to capture the degeneration features. The main objective of this paper is to provide a detailed overview for the development and analysis of this test rig. A case study with experimental vibration data is also presented to illustrate the efficacy of the developed test rig.

  14. Exp-function method for constructing exact solutions of Sharma-Tasso-Olver equation

    International Nuclear Information System (INIS)

    Erbas, Baris; Yusufoglu, Elcin

    2009-01-01

    In this paper we use the Exp-function method for the analytic treatment of Sharma-Tasso-Olver equation. New solitonary solutions are formally derived. Change of parameters, which drastically changes the characteristics of the equations, is examined. It is shown that the Exp-function method provides a powerful mathematical tool for solving high-dimensional nonlinear evolutions in mathematical physics. The proposed schemes are reliable and manageable.

  15. checkCIF/PLATON report Datablock: exp_2b

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_2b. Bond precision:.

  16. checkCIF/PLATON report Datablock: exp_1b

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: exp_1b. Bond precision:.

  17. Investigation of Spiral Bevel Gear Condition Indicator Validation via AC-29-2C Combining Test Rig Damage Progression Data with Fielded Rotorcraft Data

    Science.gov (United States)

    Dempsey, Paula J.

    2015-01-01

    This is the final of three reports published on the results of this project. In the first report, results were presented on nineteen tests performed in the NASA Glenn Spiral Bevel Gear Fatigue Test Rig on spiral bevel gear sets designed to simulate helicopter fielded failures. In the second report, fielded helicopter HUMS data from forty helicopters were processed with the same techniques that were applied to spiral bevel rig test data. Twenty of the forty helicopters experienced damage to the spiral bevel gears, while the other twenty helicopters had no known anomalies within the time frame of the datasets. In this report, results from the rig and helicopter data analysis will be compared for differences and similarities in condition indicator (CI) response. Observations and findings using sub-scale rig failure progression tests to validate helicopter gear condition indicators will be presented. In the helicopter, gear health monitoring data was measured when damage occurred and after the gear sets were replaced at two helicopter regimes. For the helicopters or tails, data was taken in the flat pitch ground 101 rotor speed (FPG101) regime. For nine tails, data was also taken at 120 knots true airspeed (120KTA) regime. In the test rig, gear sets were tested until damage initiated and progressed while gear health monitoring data and operational parameters were measured and tooth damage progression documented. For the rig tests, the gear speed was maintained at 3500RPM, a one hour run-in was performed at 4000 in-lb gear torque, than the torque was increased to 8000 in-lbs. The HUMS gear condition indicator data evaluated included Figure of Merit 4 (FM4), Root Mean Square (RMS) or Diagnostic Algorithm 1(DA1), + 3 Sideband Index (SI3) and + 1 Sideband Index (SI1). These were selected based on their sensitivity in detecting contact fatigue damage modes from analytical, experimental and historical helicopter data. For this report, the helicopter dataset was reduced to

  18. Application of Exp-function method for (2 + 1)-dimensional nonlinear evolution equations

    International Nuclear Information System (INIS)

    Bekir, Ahmet; Boz, Ahmet

    2009-01-01

    In this paper, the Exp-function method is used to construct solitary and soliton solutions of (2 + 1)-dimensional nonlinear evolution equations. (2 + 1)-dimensional breaking soliton (Calogero) equation, modified Zakharov-Kuznetsov and Konopelchenko-Dubrovsky equations are chosen to illustrate the effectiveness of the method. The method is straightforward and concise, and its applications are promising. The Exp-function method presents a wider applicability for handling nonlinear wave equations.

  19. ExpEdit: a webserver to explore human RNA editing in RNA-Seq experiments.

    Science.gov (United States)

    Picardi, Ernesto; D'Antonio, Mattia; Carrabino, Danilo; Castrignanò, Tiziana; Pesole, Graziano

    2011-05-01

    ExpEdit is a web application for assessing RNA editing in human at known or user-specified sites supported by transcript data obtained by RNA-Seq experiments. Mapping data (in SAM/BAM format) or directly sequence reads [in FASTQ/short read archive (SRA) format] can be provided as input to carry out a comparative analysis against a large collection of known editing sites collected in DARNED database as well as other user-provided potentially edited positions. Results are shown as dynamic tables containing University of California, Santa Cruz (UCSC) links for a quick examination of the genomic context. ExpEdit is freely available on the web at http://www.caspur.it/ExpEdit/.

  20. NASA GRC's High Pressure Burner Rig Facility and Materials Test Capabilities

    Science.gov (United States)

    Robinson, R. Craig

    1999-01-01

    The High Pressure Burner Rig (HPBR) at NASA Glenn Research Center is a high-velocity. pressurized combustion test rig used for high-temperature environmental durability studies of advanced materials and components. The facility burns jet fuel and air in controlled ratios, simulating combustion gas chemistries and temperatures that are realistic to those in gas turbine engines. In addition, the test section is capable of simulating the pressures and gas velocities representative of today's aircraft. The HPBR provides a relatively inexpensive. yet sophisticated means for researchers to study the high-temperature oxidation of advanced materials. The facility has the unique capability of operating under both fuel-lean and fuel-rich gas mixtures. using a fume incinerator to eliminate any harmful byproduct emissions (CO, H2S) of rich-burn operation. Test samples are easily accessible for ongoing inspection and documentation of weight change, thickness, cracking, and other metrics. Temperature measurement is available in the form of both thermocouples and optical pyrometery. and the facility is equipped with quartz windows for observation and video taping. Operating conditions include: (1) 1.0 kg/sec (2.0 lbm/sec) combustion and secondary cooling airflow capability: (2) Equivalence ratios of 0.5- 1.0 (lean) to 1.5-2.0 (rich), with typically 10% H2O vapor pressure: (3) Gas temperatures ranging 700-1650 C (1300-3000 F): (4) Test pressures ranging 4-12 atmospheres: (5) Gas flow velocities ranging 10-30 m/s (50-100) ft/sec.: and (6) Cyclic and steady-state exposure capabilities. The facility has historically been used to test coupon-size materials. including metals and ceramics. However complex-shaped components have also been tested including cylinders, airfoils, and film-cooled end walls. The facility has also been used to develop thin-film temperature measurement sensors.

  1. 41 CFR 102-118.10 - What is a transportation audit?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is a transportation audit? 102-118.10 Section 102-118.10 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  2. 41 CFR 102-118.15 - What is a transportation payment?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is a transportation payment? 102-118.15 Section 102-118.15 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  3. Estudo da ação dos fios de categute cromado e poliglecaprone 25, na ileocistoplastia em ratos, destacando a formação de cálculos

    Directory of Open Access Journals (Sweden)

    Schauffert Marli Doroti

    2000-01-01

    Full Text Available Realizou-se um estudo da ação dos fios de categute cromado 6-0 e de poliglecaprone 25, 5-0, para determinar o fio ideal na ileocistoplastia em ratas. O maior objetivo, foi a profilaxia litiásica. Utilizaram-se 51 ratos de Wistar, que participaram de dois grupos experimentais: grupo do plano piloto (27 ratos, que foi o grupo categute (GC e grupo da tese do mestrado (24 ratos, que foi o grupo poliglecaprone (GP. Sob anestesia intraperitonial com pentobarbital sódico a 3%, todos os animais foram submetidos a ileocistoplastia, após laparotomia mediana longitudinal. Nos ratos do GC, a anastomose da bexiga urinária (aberta 0,5 cm sagitalmente no seu ápice, com a extremidade distal do segmento ileal ,era realizada por meio de pontos separados em plano único, com fio de categute cromado 6-0, e nas ratas do GP, com fio de poliglecaprone 25, 5-0. Seguiu-se a síntese da parede abdominal e recuperação anestésica. O estudo era realizado em 27, 42 e 57 dias nos animais do GC, que eram divididos em 3 subgrupos de 9 ratos. No GP, os animais eram analisados em 28 e 84 dias, por subgrupos de 12 animais. Transcorrido o tempo determinado para cada subgrupo, eram reoperados e observados os aspectos macroscópicos da cicatrização, aderências e formação de cálculos. A bexiga urinária ampliada pelo segmento ileal, era ressecada, aberta, lavada em solução salina isotônica, fixada no Líquido de Boüin, e processada , para histologia. A eutanásia era consumada com dose mínima letal anestésica. Os resultados apresentados, foram 29,6% de litíase, nas ratas do GC: 5,4% em 27dias; 10% em 42 dias e 14,25 em 57 dias do pós operatório (p.o.. Nas ratas do GP, não foram encontrados cálculos. Os estudos microscópicos, foram submetidos à análise estatística (a £ a 0,05, e utilizados para outro trabalho científico. Conclui-se: na ileocistoplastia com categute cromado 6-0, há 29,6% de cálculos, do 27o ao 57o dia p.o. e com o uso do fio de

  4. Lifting devices with minimum effort for testing, maintenance and repair at the example of a lifting rig for core internals

    Energy Technology Data Exchange (ETDEWEB)

    Pache, Martin [Westinghouse Electric Germany GmbH (Germany); Wiesendanger, Robert [Kernkraftwerk Beznau, NOK (Switzerland)

    2008-07-01

    Beznau is a Westinghouse built nuclear power plant in the Aargau area Switzerland. It consists of two PWR units, each providing 365 MWe net capacity. The units were set into operation in 1969 and 1972, respectively, and hold an unlimited license for operation, provided they continue to fulfill current legal and security requirements. Beznau's previous lifting rigs for core internals required a high effort in testing and maintenance. Moreover, a damage to one of the rigs nearly resulted in the inoperability of the rig. However, no element of the load chain was affected, so there was no danger of a crash, but it could have caused an extended outage. Hence, it was decided to replace the lifting rigs with a state-of-the-art functional design that reflects modern requirements on maintenance and testing. Although the plant was built to ASME standards and codes, the new lifting rigs have been designed to German KTA code for lifting devices (KTA 3902 / 3903 for equipment with increased requirements, as per section 4.3 of KTA 3902). Given KTA's demands on periodic testing, one main requirement on the new design was to minimize the testing effort for the new rigs. (orig.)

  5. Deployment and evaluation of a dual-sensor autofocusing method for on-machine measurement of patterns of small holes on freeform surfaces.

    Science.gov (United States)

    Chen, Xiaomei; Longstaff, Andrew; Fletcher, Simon; Myers, Alan

    2014-04-01

    This paper presents and evaluates an active dual-sensor autofocusing system that combines an optical vision sensor and a tactile probe for autofocusing on arrays of small holes on freeform surfaces. The system has been tested on a two-axis test rig and then integrated onto a three-axis computer numerical control (CNC) milling machine, where the aim is to rapidly and controllably measure the hole position errors while the part is still on the machine. The principle of operation is for the tactile probe to locate the nominal positions of holes, and the optical vision sensor follows to focus and capture the images of the holes. The images are then processed to provide hole position measurement. In this paper, the autofocusing deviations are analyzed. First, the deviations caused by the geometric errors of the axes on which the dual-sensor unit is deployed are estimated to be 11 μm when deployed on a test rig and 7 μm on the CNC machine tool. Subsequently, the autofocusing deviations caused by the interaction of the tactile probe, surface, and small hole are mathematically analyzed and evaluated. The deviations are a result of the tactile probe radius, the curvatures at the positions where small holes are drilled on the freeform surface, and the effect of the position error of the hole on focusing. An example case study is provided for the measurement of a pattern of small holes on an elliptical cylinder on the two machines. The absolute sum of the autofocusing deviations is 118 μm on the test rig and 144 μm on the machine tool. This is much less than the 500 μm depth of field of the optical microscope. Therefore, the method is capable of capturing a group of clear images of the small holes on this workpiece for either implementation.

  6. Improving mixing efficiency in a closed circuit water flow rig for ...

    African Journals Online (AJOL)

    . ... pulse velocity method, indicating that the flow meters functioned correctly. The modified rig with scaled-up mixing techniques could serve as platform for training in evaluating mixing vessels and flow meters in industrial process plants.

  7. ROBÔ PARA INSPEÇÃO DE ÁREAS CLASSIFICADAS E DE DIFÍCIL ACESSO COM TRANSMISSÃO DE IMAGENS SEM FIO

    Directory of Open Access Journals (Sweden)

    Jonathan Pereira

    2010-01-01

    Full Text Available Mediante a necessidade de monitoramento de áreas de difícil acesso ao homem ou áreas que levem risco a sua integridade física, esta pesquisa tem por objetivo construir um robô que faça a captura de imagens por um sistema totalmente sem fio e controlado por computador. Para isso fez-se necessário o projeto e implementação mecânica e eletrônica de um protótipo composto de servomotores, um microcontrolador, um módulo de rádio para a comunicação entre robô e computador e um sistema de captação e transmissão de imagem sem fio. Para a implementação do software que proporciona a execução de comandos remotos, desenvolveu-se uma aplicação utilizando o ambiente C++ Builder®. Em toda a implementação fez-se uso de conceitos visto nas disciplinas de programação de computadores, eletrônica analógica e digital, microcontroladores, sistema de transmissão de dados e mecânica. PALAVRAS-CHAVE: Monitoramento, Robô, microcontrolador.

  8. Geração de solicitação de serviço para inspeção e manutenção em máquinas industriais utilizando redes sem fio

    OpenAIRE

    Ornelas, Fernando César de

    2004-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Ciência da Computação Nesta dissertação apresentamos um estudo de caso de aplicação real de rede sem fio, cujo objetivo é a melhoria nas atividades de inspeção e a identificação da necessidade de manutenção em máquinas e equipamentos na área industrial. Fazendo utilização de redes sem fios e de unidades móveis, que se conectam periodicamente a uma rede estruturada, permitimos a...

  9. 33 CFR 118.110 - Daymarks and lateral lighting on bridges.

    Science.gov (United States)

    2010-07-01

    ... bridges. 118.110 Section 118.110 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.110 Daymarks and lateral lighting on bridges. (a... through bridges with U.S. aids to navigation system lateral marks and lights installed on the...

  10. 28 CFR 0.118 - Office of Chief Administrative Hearing Officer.

    Science.gov (United States)

    2010-07-01

    ... Officer. 0.118 Section 0.118 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Executive Office for Immigration Review § 0.118 Office of Chief Administrative Hearing... Law Judges in performance of their duties in accordance with 8 U.S.C. 1324 A and B. ...

  11. Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.

    Science.gov (United States)

    Fitzgerald, Megan E; Rawling, David C; Potapova, Olga; Ren, Xiaoming; Kohlway, Andrew; Pyle, Anna Marie

    2017-02-17

    RIG-I is an innate immune receptor that detects and responds to infection by deadly RNA viruses such as influenza, and Hepatitis C. In the cytoplasm, RIG-I is faced with a difficult challenge: it must sensitively detect viral RNA while ignoring the abundance of host RNA. It has been suggested that RIG-I has a ‘proof-reading’ mechanism for rejecting host RNA targets, and that disruptions of this selectivity filter give rise to autoimmune diseases. Here, we directly monitor RNA proof-reading by RIG-I and we show that it is controlled by a set of conserved amino acids that couple RNA and ATP binding to the protein (Motif III). Mutations of this motif directly modulate proof-reading by eliminating or enhancing selectivity for viral RNA, with major implications for autoimmune disease and cancer. More broadly, the results provide a physical explanation for the ATP-gated behavior of SF2 RNA helicases and receptor proteins.

  12. 42 CFR 401.118 - Deletion of identifying details.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Deletion of identifying details. 401.118 Section 401.118 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Deletion of identifying details. When CMS publishes or otherwise makes available an opinion or order...

  13. Development of a remote data acquisition and graphic display system for the sodium rigs

    International Nuclear Information System (INIS)

    Rajendran, A.; Sylvia, J.I.; Swaminathan, K.

    1992-01-01

    This paper describes the development of a Remote Data Acquisition System for Sodium Rigs. Seven data loggers, an alarm monitor and a PLC are geographically distributed in two sodium rigs over a distance of 500 m. A serial data highway based on RS485 transceivers has been constructed to remotely acquire data from these stations. The field stations are connected to the data highway in a multi drop fashion. A PC/AT computer on the same bus remotely acquires and monitors the data from the field stations. (author). 3 refs., 2 figs

  14. Characterization of Endogenous Plasmids from Lactobacillus salivarius UCC118▿ †

    OpenAIRE

    Fang, Fang; Flynn, Sarah; Li, Yin; Claesson, Marcus J.; van Pijkeren, Jan-Peter; Collins, J. Kevin; van Sinderen, Douwe; O'Toole, Paul W.

    2008-01-01

    The genome of Lactobacillus salivarius UCC118 comprises a 1.83-Mb chromosome, a 242-kb megaplasmid (pMP118), and two smaller plasmids of 20 kb (pSF118-20) and 44 kb (pSF118-44). Annotation and bioinformatic analyses suggest that both of the smaller plasmids replicate by a theta replication mechanism. Furthermore, it appears that they are transmissible, although neither possesses a complete set of conjugation genes. Plasmid pSF118-20 encodes a toxin-antitoxin system composed of pemI and pemK h...

  15. Oxidation of a Silica-Containing Material in a Mach 0.3 Burner Rig

    Science.gov (United States)

    Nguyen, QuynhGiao N.; Cuy, Michael D.; Gray, Hugh R. (Technical Monitor)

    2002-01-01

    A primarily silica-containing material with traces of organic compounds, as well as aluminum and calcium additions, was exposed to a Mach 0.3 burner rig at atmospheric pressure using jet fuel. The sample was exposed for 5 continuous hours at 1370 C. Post exposure x-ray diffraction analyses indicate formation of cristobalite, quartz, NiO and Spinel (Al(Ni)CR2O4). The rig hardware is composed of a nickel-based superalloy with traces of Fe. These elements are indicated in the energy dispersive spectroscopy (EDS) results. This material was studied as a candidate for high temperature applications under an engine technology program.

  16. Characterization of Endogenous Plasmids from Lactobacillus salivarius UCC118▿ †

    Science.gov (United States)

    Fang, Fang; Flynn, Sarah; Li, Yin; Claesson, Marcus J.; van Pijkeren, Jan-Peter; Collins, J. Kevin; van Sinderen, Douwe; O'Toole, Paul W.

    2008-01-01

    The genome of Lactobacillus salivarius UCC118 comprises a 1.83-Mb chromosome, a 242-kb megaplasmid (pMP118), and two smaller plasmids of 20 kb (pSF118-20) and 44 kb (pSF118-44). Annotation and bioinformatic analyses suggest that both of the smaller plasmids replicate by a theta replication mechanism. Furthermore, it appears that they are transmissible, although neither possesses a complete set of conjugation genes. Plasmid pSF118-20 encodes a toxin-antitoxin system composed of pemI and pemK homologs, and this plasmid could be cured when PemI was produced in trans. The minimal replicon of pSF118-20 was determined by deletion analysis. Shuttle vector derivatives of pSF118-20 were generated that included the replication region (pLS203) and the replication region plus mobilization genes (pLS208). The plasmid pLS203 was stably maintained without selection in Lactobacillus plantarum, Lactobacillus fermentum, and the pSF118-20-cured derivative strain of L. salivarius UCC118 (strain LS201). Cloning in pLS203 of genes encoding luciferase and green fluorescent protein, and expression from a constitutive L. salivarius promoter, demonstrated the utility of this vector for the expression of heterologous genes in Lactobacillus. This study thus expands the knowledge base and vector repertoire of probiotic lactobacilli. PMID:18390685

  17. Threshold Assessment of Gear Diagnostic Tools on Flight and Test Rig Data

    Science.gov (United States)

    Dempsey, Paula J.; Mosher, Marianne; Huff, Edward M.

    2003-01-01

    A method for defining thresholds for vibration-based algorithms that provides the minimum number of false alarms while maintaining sensitivity to gear damage was developed. This analysis focused on two vibration based gear damage detection algorithms, FM4 and MSA. This method was developed using vibration data collected during surface fatigue tests performed in a spur gearbox rig. The thresholds were defined based on damage progression during tests with damage. The thresholds false alarm rates were then evaluated on spur gear tests without damage. Next, the same thresholds were applied to flight data from an OH-58 helicopter transmission. Results showed that thresholds defined in test rigs can be used to define thresholds in flight to correctly classify the transmission operation as normal.

  18. Hot corrosion testing of Ni-based alloys and coatings in a modified Dean rig

    Science.gov (United States)

    Steward, Jason Reid

    Gas turbine blades are designed to withstand a variety of harsh operating conditions. Although material and coating improvements are constantly administered to increase the mean time before turbine refurbishment or replacement, hot corrosion is still considered as the major life-limiting factor in many industrial and marine gas turbines. A modified Dean rig was designed and manufactured at Tennessee Technological University to simulate the accelerated hot corrosion conditions and to conduct screening tests on the new coatings on Ni-based superalloys. Uncoated Ni-based superalloys, Rene 142 and Rene 80, were tested in the modified Dean rig to establish a testing procedure for Type I hot corrosion. The influence of surface treatments on the hot corrosion resistance was then investigated. It was found that grit-blasted specimens showed inferior hot corrosion resistance than that of the polished counterpart. The Dean rig was also used to test model MCrAlY alloys, pack cementation NiAl coatings, and electro-codeposited MCrAlY coatings. Furthermore, the hot corrosion attack on the coated-specimens were also assessed using a statistical analysis approach.

  19. Evaluation of wheel/rail contact mechanics : roller rig concept design review.

    Science.gov (United States)

    2014-07-01

    A need exists for a new test rig design with advanced sensing technologies that will allow the railroad industry and regulatory : agencies to better understand the wheel-rail contact dynamics and mechanics, especially as it pertains to high-speed rai...

  20. GenExp: an interactive web-based genomic DAS client with client-side data rendering.

    Directory of Open Access Journals (Sweden)

    Bernat Gel Moreno

    Full Text Available BACKGROUND: The Distributed Annotation System (DAS offers a standard protocol for sharing and integrating annotations on biological sequences. There are more than 1000 DAS sources available and the number is steadily increasing. Clients are an essential part of the DAS system and integrate data from several independent sources in order to create a useful representation to the user. While web-based DAS clients exist, most of them do not have direct interaction capabilities such as dragging and zooming with the mouse. RESULTS: Here we present GenExp, a web based and fully interactive visual DAS client. GenExp is a genome oriented DAS client capable of creating informative representations of genomic data zooming out from base level to complete chromosomes. It proposes a novel approach to genomic data rendering and uses the latest HTML5 web technologies to create the data representation inside the client browser. Thanks to client-side rendering most position changes do not need a network request to the server and so responses to zooming and panning are almost immediate. In GenExp it is possible to explore the genome intuitively moving it with the mouse just like geographical map applications. Additionally, in GenExp it is possible to have more than one data viewer at the same time and to save the current state of the application to revisit it later on. CONCLUSIONS: GenExp is a new interactive web-based client for DAS and addresses some of the short-comings of the existing clients. It uses client-side data rendering techniques resulting in easier genome browsing and exploration. GenExp is open source under the GPL license and it is freely available at http://gralggen.lsi.upc.edu/recerca/genexp.

  1. Application of Exp-function method to potential Kadomtsev-Petviashvili equation

    International Nuclear Information System (INIS)

    Xian Daquan; Dai Zhengde

    2009-01-01

    Exact periodic kink-wave solution, periodic soliton and doubly periodic solutions for the potential Kadomtsev-Petviashvii (PKP) equation are obtained using Exp-function method with the help of Maple computation.

  2. Study on aero-dynamic characteristics of the sloop rig (continued); Sloop ring no kuriki tokusei no ichikaiseki (zoku)

    Energy Technology Data Exchange (ETDEWEB)

    Shinkai, A.; Iyoda, H. [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1997-09-04

    A numerical simulation method was formerly provided for analyzing aero-dynamic characteristics of sloop rig by the vortex distribution method. For this method, aero-dynamic characteristics of the sloop rib were formulated by treating air flow around sail as a two-dimensional problem and by assuming sail as a membrane. The sloop rig is a yacht for more than two persons, which is the most popular form of rig. A main sail and a jib sheet are fixed on a mast. In this study, the method developed based on the panel method was introduced for analyzing the effects of jib sheet which can control the jib trim angle. Generality of the present aero-dynamic characteristics was enhanced, and problems of the analysis method were extracted through the numerical simulation of a yacht with sloop rig. Influence of the position of fairleader on the aero-dynamic characteristics was qualitatively grasped by considering the effects of jib sheet and by trimming the elevation into ideal one. 6 refs., 11 figs.

  3. 47 CFR 25.118 - Modifications not requiring prior authorization.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Modifications not requiring prior authorization. 25.118 Section 25.118 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Applications and Licenses General Application Filing Requirements § 25...

  4. 40 CFR 81.118 - Southwest Missouri Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Region. 81.118 Section 81.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.118 Southwest Missouri Intrastate Air Quality Control Region. The Southwest Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  5. 41 CFR 102-118.20 - Who is subject to this part?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Who is subject to this part? 102-118.20 Section 102-118.20 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  6. Development of Induction Brazing System for Sealing Instrumentation Feed through Part of Nuclear Fuel Test Rig

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jintae; Kim, Kahye; Heo, Sungho; Ahn, Sungho; Joung, Changyoung; Son, Kwangjae; Jung, Yangil [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-12-15

    To test the performance of nuclear fuels, coolant needs to be circulated through the test rig installed in the test loop. Because the pressure and temperature of the coolant is 15.5 MPa and 300 .deg. C respectively, coolant sealing is one of the most important processes in fabricating a nuclear fuel test rig. In particular, 15 instrumentation cables installed in a test rig pass through the pressure boundary, and brazing is generally applied as a sealing method. In this study, an induction brazing system has been developed using a high frequency induction heater including a vacuum chamber. For application in the nuclear field, BNi2 should be used as a paste, and optimal process variables for Ni brazing have been found by several case studies. The performance and soundness of the brazed components has been verified by a tensile test, cross section test, and sealing performance test.

  7. Protocolo para a distribuição de informações de canais em redes em malha sem fio

    Directory of Open Access Journals (Sweden)

    Roni Francis Shigueta

    2014-04-01

    Full Text Available Este artigo apresenta um protocolo para a distribuição de informações de canais em uma rede em malha sem fio. O canal corresponde à faixa de frequência na qual dois dispositivos sem fio (nós da rede podem se comunicar. O protocolo apresentado permite criar um repositório que contém os canais que estão disponíveis em um dispositivo para que se comunique com o seu nó vizinho. A partir das informações desse repositório, os dispositivos podem tomar decisões de alocação de canais, baseadas em algum critério, como por exemplo, a menor interferência gerada na rede. Dependendo da quantidade de canais disponíveis, é possível atribuir canais diferentes aos enlaces da rede (par de nós, permitindo transmissões simultâneas. A simulação do protocolo é realizada por meio de canais de frequência do padrão IEEE 802.11b. Apesar das simulações serem realizadas nesse padrão, o protocolo pode ser adaptado para operar em outras faixas de frequência. Os resultados demonstram que a partir dos valores dos canais transmitidos através de mensagens de hello, é possível encontrar os canais comuns entre dois nós, realizando a intersecção entre a lista de canais do nó vizinho com a lista do nó local.

  8. Complete Genome Sequence of the Campylobacter ureolyticus Clinical Isolate RIGS 9880

    DEFF Research Database (Denmark)

    Miller, William G; Yee, Emma; On, Stephen L W

    2015-01-01

    The emerging pathogen Campylobacter ureolyticus has been isolated from human and animal genital infections, human periodontal disease, domestic and food animals, and from cases of human gastroenteritis. We report the whole-genome sequence of the human clinical isolate RIGS 9880, which is the first...

  9. Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

    Energy Technology Data Exchange (ETDEWEB)

    Devarkar, Swapnil C.; Wang, Chen; Miller, Matthew T.; Ramanathan, Anand; Jiang, Fuguo; Khan, Abdul G.; Patel, Smita S.; Marcotrigiano, Joseph

    2016-01-05

    The cytosolic innate immune receptor Retinoic Acid Inducible Gene-I (RIG-I) is the principal detector of pathogenic RNAs carrying a 5'-triphosphate (5'ppp). Self RNAs like mRNAs evade recognition by RIG-I due to posttranscriptional modifications like 5'-end capping with 7-methyl guanosine (m7G) and 2'-O-methylation of 5'-end nucleotides. Viruses have also evolved mechanisms to mimic these modifications, which in part is believed to aid in immune evasion. Currently, it is unclear how these modifications modulate RIG-I recognition. This paper provides structural and mechanistic insights into the roles of the m7G cap and 2'-O-methylation in RIG-I evasion. We show that RIG-I accommodates the m7G base while maintaining the 5'ppp contacts and can recognize Cap-0 RNAs but not Cap-1.

  10. Apparatus Would Measure Temperatures Of Ball Bearings

    Science.gov (United States)

    Gibson, John C.; Fredricks, Thomas H.

    1995-01-01

    Rig for testing ball bearings under radial and axial loads and measuring surface temperatures undergoing development. Includes extensible thermocouples: by means of bellows as longitudinal positioners, thermocouples driven into contact with bearing balls to sense temperatures immediately after test run. Not necessary to disassemble rig or to section balls to obtain indirect indications of maximum temperatures reached. Thermocouple measurements indicate temperatures better than temperature-sensitive paints.

  11. Automated FiO2-SpO2 control system in neonates requiring respiratory support: a comparison of a standard to a narrow SpO2 control range.

    Science.gov (United States)

    Wilinska, Maria; Bachman, Thomas; Swietlinski, Janusz; Kostro, Maria; Twardoch-Drozd, Marta

    2014-05-28

    Managing the oxygen saturation of preterm infants to a target range has been the standard of care for a decade. Changes in target ranges have been shown to significantly impact mortality and morbidity. Selecting and implementing the optimal target range are complicated not only by issues of training, but also the realities of staffing levels and demands. The potential for automatic control is becoming a reality. Results from the evaluation of different systems have been promising and our own experience encouraging. This study was conducted in two tertiary level newborn nurseries, routinely using an automated FiO2-SpO2 control system (Avea-CLiO2, Yorba Linda CA, USA). The aim of this study was to compare the performance of the system as used routinely (set control range of 87-93% SpO2), to a narrower higher range (90-93%). We employed a 12-hour cross-over design with the order of control ranges randomly assigned for each of up to three days. The primary prospectively identified end points were time in the 87-93% SpO2 target range, time at SpO2 extremes and the distribution of the SpO2 exposure. Twenty-one infants completed the study. The infants were born with a median EGA of 27 weeks and studied at a median age of 17 days and weight of 1.08 kg. Their median FiO2 was 0.32; 8 were intubated, and the rest noninvasively supported (7 positive pressure ventilation and 6 CPAP). The control in both arms was excellent, and required less than 2 manual FiO2 adjustments per day. There were no differences in the three primary endpoints. The narrower/higher set control range resulted in tighter control (IQR 3.0 vs. 4.3 p < 0.001), and less time with the SpO2 between 80-86 (6.2% vs. 8.4%, p = 0.006). We found that a shift in the median of the set control range of an automated FiO2-SpO2 control system had a proportional effect on the median and distribution of SpO2 exposure. We found that a dramatic narrowing of the set control range had a disproportionally smaller impact. Our

  12. Sources de photons uniques et expérience à choix retardé de Wheeler : la dualité onde corpuscule à l'épreuve de l'expérience

    Science.gov (United States)

    Jacques, V.

    Young's double-slit experiment realized with particles sent one at a time through an interferometer is at the heart of quantum mechanics. The striking feature is that the phenomenon of interference, interpreted as a wave following simultaneously two paths, is incompatible with our common sense representation of a particle following one route or the other but not both. The work described in this book is dedicated to the study of wave-particle duality for a single photon emitted by the triggered photoluminescence of a single NV color center in a diamond nanocrystal. We first present the realization of a single-photon interference experiment using a Fresnel's biprism, in a scheme equivalent to the standard Young's double-slit textbook experiment. We then discuss the complementarity between interference and which-path information in this two-path interferometer. We finally describe the experimental realization of Wheeler's delayed-choice gedanken experiment, which is a fascinating and subtle illustration of wave-particle duality. In such experiment, the choice either to observe interference fringes, obviously associated to a wave-like behavior, or to know which path of the interferometer has been followed, according to a particle-like behavior, is made whereas the photon has already entered into the interferometer. Furthermore, the choice is made by a quantum random number generator and is relativistically separated from the entering of the photon into the interferometer. The results of that experiment show once again that no classical physical reality can be attributed to the photon independent of the measurement apparatus, as stated by the complementarity principle. La théorie quantique nécessite de renoncer à certaines images classiques héritées du sens commun. Elle stipule en particulier une description duale de la lumière et de la matière, présentant simultanément les propriétés d'une onde et d'une particule et conduisant ainsi à des repr

  13. A REAL TIME DECISION SUPPORT SYSTEM FOR THE ADJUSTMENT OF SAILBOAT RIGGING

    Directory of Open Access Journals (Sweden)

    Inmaculada Ortigosa

    2016-01-01

    Full Text Available The operational complexity and performance requirements of modern racing yachts demand the use of advanced applications, such as a decision support system (DSS able to assist crew members during navigation. In this article, the authors describe a near-time computational solver as the main piece of a DSS which analyses and monitors the behaviour of sails and rigging. The solver is made up of two different interconnected tools: an iterative Fluid-Structure Interaction algorithm and an advanced Wireless Sensor Network to monitor rigging. The real-time DSS quantifies crew manoeuvres in physical terms, which are reproduced by a simulation program. It can be used in the design phase of sailing yachts and as an aid for real-time boat performance optimisation and accident prevention. This novel DSS is a useful tool for navigation, especially in races.

  14. The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I

    Directory of Open Access Journals (Sweden)

    Chunyuan Zhao

    2017-11-01

    Full Text Available Retinoic acid-inducible gene-I (RIG-I-like receptors (RLRs, including melanoma differentiation-associated gene 5 (MDA5 and RIG-I, are crucial for host recognition of non-self RNAs, especially viral RNA. Thus, the expression and activation of RLRs play fundamental roles in eliminating the invading RNA viruses and maintaining immune homeostasis. However, how RLR expression is tightly regulated remains to be further investigated. In this study, we identified a major histocompatibility complex (MHC-encoded gene, tripartite interaction motif 40 (TRIM40, as a suppressor of RLR signaling by directly targeting MDA5 and RIG-I. TRIM40 binds to MDA5 and RIG-I and promotes their K27- and K48-linked polyubiquitination via its E3 ligase activity, leading to their proteasomal degradation. TRIM40 deficiency enhances RLR-triggered signaling. Consequently, TRIM40 deficiency greatly enhances antiviral immune responses and decreases viral replication in vivo. Thus, we demonstrate that TRIM40 limits RLR-triggered innate activation, suggesting TRIM40 as a potential therapeutic target for the control of viral infection.

  15. A New Design of the Universal Test Rig to Measure the Wear Characterizations of Polymer Acetal Gears (Spur, Helical, Bevel, and Worm

    Directory of Open Access Journals (Sweden)

    Samy Yousef

    2015-01-01

    Full Text Available This work aims to study the wear characterization of common types of acetal polymer gears (spur, helical, bevel, and worm using a new TS universal test rig, in order to obtain reliable results and as a reference when compared with acetal nanocomposite gears later. The TS universal test rig consists of three different units that are connected by a main driver shaft and a pair of constantly meshing metal spur gears, which transfer power to the bevel and worm test units. The first unit is used to test the bevel gears, the second unit is used to test the spur and helical gears, and the third unit is used to test the worm gears. The loading mechanism is similarly designed to block the brake mechanism. Hobbing and milling machines were used to machine an injection-moulded polymer flanges and produce the tested gears. All gear pairs, except the worm gear, have identical gear ratios. The experiments were performed at speed 1420 rpm and the torque was 4 Nm. The results showed that the wear rates (in the form of weight loss of spur gears were consistent with the previous results and the other gear types had larger wear rates.

  16. Tensile strength study of the abdominal wall following laparotomy synthesis using three types of surgical wires in Wistar rats Estudo da resistência tênsil da parede abdominal após síntese de laparotomia usando três tipos de fios cirúrgicos em ratos Wistar

    Directory of Open Access Journals (Sweden)

    Lucas Félix Rossi

    2008-02-01

    Full Text Available PURPOSE: To study the tensile strength of the abdominal wall following laparotomy synthesis utilizing three types of surgical wires. METHODS: Thirty Wistar rats were randomized into three groups of ten rats each. Each group underwent a 3cm-laparotomy which was closed with 3-0 polyglactin 910, polyglecrapone and catgut wires. After 63 days, euthanasia was performed and part of the abdominal wall was removed with which a strip was produced measuring 2.0 cm in length by 6.0 cm in width comprising the abdominal muscles with the implanted mesh. The sample was fixed in a mechanical test machine in which constant force was applied contrary to the tissue strips. Maximum force was considered, expressed in Newton, until full rupture of the tissue occurred. The non-parametrical Kruskal - Wallis test was used for the statistical analysis, admitting pOBJETIVO: Estudar a resistência tênsil da parede abdominal após síntese de laparotomia utilizando três tipos de fios cirúrgicos. MÉTODOS: Trinta ratos da linhagem Wistar randomizados em três grupos de dez exemplares cada um. Em cada grupo fez-se uma laparotomia de dois centímetros que foi fechada com fios 3-0 de poliglactina 910, poliglecaprone e categute. Após 63 dias, foi feita a eutanásia e retirou-se uma área da parede abdominal com a qual fez-se uma tira medindo 2,0 cm de comprimento por 6,0 cm de largura englobando os músculos abdominais com a tela implantada. A amostra foi fixada em máquina de ensaios mecânicos na qual se aplicou força constante contrária às tiras de tecido. Foi considerada a força máxima expressa em Newton até ocorrer a ruptura total da amostra. Para a análise estatística, utilizou-se teste não paramétrico de Kruskal - Wallis admitindo-se p<0,05. RESULTADOS: A média de resistência do grupo categute foi ligeiramente menor (33.50 N ao da poliglactina (34.23 N, sendo essa diferença não estatisticamente significativa (p=0,733. O grupo poliglecaprone foi o que

  17. A universal suspension test rig for electrohydraulic active and passive automotive suspension system

    Directory of Open Access Journals (Sweden)

    Mahmoud Omar

    2017-12-01

    Full Text Available A fully active electro-hydraulic and passive automotive quarter car suspensions with their experimental test-rigs are designed and implemented. Investigation of the active performance compared against the passive is performed experimentally and numerically utilizing SIMULINK's Simscape library. Both systems are modeled as single-degree-of-freedom in order to simplify the validation process. Economic considerations were considered during the rig's implementation. The rig consists of two identical platforms fixed side by side allowing testing two independent suspensions simultaneously. Position sensors for sprung and unsprung masses on both platforms are installed. The road input is introduced by a cam and a roller follower mechanism driven by 1.12 kW single phase induction motor with speed reduction assembly. The active hydraulic cylinder was the most viable choice due to its high power-to-weight ratio. The active control is of the proportional-integral-differential (PID type. Though this technique is quite simple and not new, yet the emphasis of this paper is the engineering, design and implementation of the experimental setup and controller. A successful validation process is performed. Ride comfort significantly improved with active suspension, as shown by the results; 24.8% sprung mass vibration attenuation is achieved. The details of the developed system with the analytical and experimental results are presented. Keywords: Active suspension, Passive suspension, Servo, Hydraulic, Control, PID

  18. An accurate redetermination of the 118Sn binding energy

    International Nuclear Information System (INIS)

    Borzakov, S.B.; Panteleev, Ts.Ts.; Telezhnikov, S.A.; Chrien, R.E.; Faikow-Stanczyk, H.; Grigor'ev, Yu.V.; Pospisil, S.; Smotritskij, L.M.

    2001-01-01

    The energy of well-known strong γ-line from 198 Au, the 'gold standard', has been modified in the light of new adjustments in the fundamental constants and the value of 411.80176(12) keV was determined which is 0.29 eV lower than the latest 1999 value. An energy calibration procedure for determining the neutron binding energy, B n , from complicated (n,γ)-spectra has been developed. A mathematically simple minimization function consisting only of terms having as parameters the coefficients of the energy calibration curve (polynomial) is used. A priori information about the relationships among the energies of different peaks on the spectrum was taken into account by a Monte Carlo simulation. The procedure was used in obtaining of B n for 118 Sn and 64 Cu. The γ-ray spectrum from thermal neutron radiative capture by 117 Sn has been measured on the IBR-2 pulsed reactor. γ-rays were detected by a 72 cm 2 HPGe-detector. B n for 64 Cu was obtained from two γ-spectra. One spectrum was measured on the IBR-2 by the same detector. The other spectrum was measured with a pair spectrometer at the Brookhaven High Flux Beam Reactor. From these two spectra B n for 64 Cu was determined equal to 7915.52(8) keV. The mean value of two most precise results of B n for 118 Sn was determined to be 9326.35(9) keV. The B n for 57Fe was determined to be 7646.08(9) keV

  19. Wind tunnel tests of Risø-B1-18 and Risø-B1-24

    DEFF Research Database (Denmark)

    Fuglsang, P.; Bak, Christian; Gaunaa, Mac

    2003-01-01

    This report contains 2D measurements of the Risø-B1-18 and Risø-B1-24 airfoils. The aerodynamic properties were derived from pressure measurements on the airfoil surface and in the wake. The measurements were conducted in the VELUX open jet wind tunnel,which has a background turbulence intensity...

  20. Flap testing on the rotating test rig in the INDUFLAP project

    DEFF Research Database (Denmark)

    Barlas, Athanasios; Aagaard Madsen, Helge; Enevoldsen, Karen

    Tests of a prototype Controllable Rubber Trailing Edge Flap (CRTEF) are performed on the rotating test rig at the Risø campus of DTU. The general description and objectives are presented, along with an overview of sensors on the setup and the test cases. The post-processing of data is discussed...

  1. 33 CFR 118.5 - Penalty for failure to maintain.

    Science.gov (United States)

    2010-07-01

    ... States who fails or refuses to maintain such lights and other signals, or to obey any of the lawful rules... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Penalty for failure to maintain. 118.5 Section 118.5 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY...

  2. Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases

    NARCIS (Netherlands)

    Mesman, Annelies W.; Zijlstra-Willems, Esther M.; Kaptein, Tanja M.; de Swart, Rik L.; Davis, Meredith E.; Ludlow, Martin; Duprex, W. Paul; Gack, Michaela U.; Gringhuis, Sonja I.; Geijtenbeek, Teunis B. H.

    2014-01-01

    Dendritic cells (DCs) are targets of measles virus (MV) and play central roles in viral dissemination. However, DCs express the RIG-I-like receptors (RLRs) RIG-I and Mda5 that sense MV and induce type I interferon (IFN) production. Given the potency of this antiviral response, RLRs are tightly

  3. Measles virus suppresses RIG-I-like receptor activation in dendritic cells via DC-SIGN-mediated inhibition of PP1 phosphatases

    NARCIS (Netherlands)

    A.W. Mesman (Annelies ); E.M. Zijlstra-Willems (Esther); T.M. Kaptein (Tanja); R.L. de Swart (Rik); M.E. Davis (Meredith); M. Ludlow (Martin); W.P. Duprex (Paul); M.U. Gack (Michaela); S.I. Gringhuis (Sonja); T.B.H. Geijtenbeek (Teunis)

    2014-01-01

    textabstractDendritic cells (DCs) are targets of measles virus (MV) and play central roles in viral dissemination. However, DCs express the RIG-I-like receptors (RLRs) RIG-I and Mda5 that sense MV and induce type I interferon (IFN) production. Given the potency of this antiviral response, RLRs are

  4. ParaExp Using Leapfrog as Integrator for High-Frequency Electromagnetic Simulations

    Science.gov (United States)

    Merkel, M.; Niyonzima, I.; Schöps, S.

    2017-12-01

    Recently, ParaExp was proposed for the time integration of linear hyperbolic problems. It splits the time interval of interest into subintervals and computes the solution on each subinterval in parallel. The overall solution is decomposed into a particular solution defined on each subinterval with zero initial conditions and a homogeneous solution propagated by the matrix exponential applied to the initial conditions. The efficiency of the method depends on fast approximations of this matrix exponential based on recent results from numerical linear algebra. This paper deals with the application of ParaExp in combination with Leapfrog to electromagnetic wave problems in time domain. Numerical tests are carried out for a simple toy problem and a realistic spiral inductor model discretized by the Finite Integration Technique.

  5. Isolation and characterization of the human homologue of rig and its pseudogenes: The functional gene has features characteristic of housekeeping genes

    International Nuclear Information System (INIS)

    Shiga, Kiyoto; Yamamoto, Hiroshi; Okamoto, Hiroshi

    1990-01-01

    Rig (rat insulinoma gene) was first isolated from a cDNA library of rat insulinomas and has been found to be activated in various human tumors such as insulinomas, esophageal cancers, and colon cancers. Here the authors isolated the human homologue of rig from a genomic DNA library constructed from a human esophageal carcinoma and determined its complete nucleotide sequence. The gene is composed of about 3,000 nucleotides and divided into four exons separated by three introns: exon 3 encodes the nuclear location signal and the DNA-binding domain of the RIG protein. The transcription initiation site was located at -46 base pairs upstream from the first ATG codon. The 5'-flanking region of the gene has no apparent TATA-box or CAAT-box sequence. However, two GC boxes are found at -189 and -30 base pairs upstream from the transcription initiation site and five GC boxes are also found in introns 1 and 2. The gene is bounded in the 5' region by CpG islands, regions of DNA with a high GC content and a high frequency of CpG dinucleotides relative to the bulk genome. Furthermore, the human genome contains at least six copies of RIG pseudogenes, and four of them have the characteristics of processed pseudogenes. From these results together with the finding that RIG is expressed in a wide variety of tissues and cells, they speculate that RIG belongs to the class of housekeeping genes, whose products are necessary for the growth of all cell types

  6. IPR 118 - Bread wheat cultivar

    Directory of Open Access Journals (Sweden)

    Carlos Roberto Riede

    2007-01-01

    Full Text Available Wheat cultivar IPR 118 developed by IAPAR has a good yield potential and is widely adapted. It is earlymaturing and moderately tolerant to shattering and soil aluminum, moderately resistant to leaf rust and presents high glutenstrength for bread-making. The overall yield exceeded controls by 13%.

  7. 32 CFR 536.118 - Related statutes for maritime claims.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Related statutes for maritime claims. 536.118... ACCOUNTS CLAIMS AGAINST THE UNITED STATES Maritime Claims § 536.118 Related statutes for maritime claims... under the AMCSA is not mandatory for causes of action as it is for the SIAA or PVA. (b) Similar maritime...

  8. Eletroerosão por fio em metal duro para ferramentas de estampagem de lâminas de motores elétricos

    OpenAIRE

    Hespanhol, Heber de Carvalho

    2009-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Mecânica. O processo de eletroerosão por fio é utilizado atualmente na fabricação da maioria das matrizes e punções de metal duro (carbeto de tungstênio), usados em ferramentas de estampagem de aços para motores elétricos. As indústrias de eletrodomésticos, motores elétricos industriais, transformadores e compressores herméticos, utilizam ferramentas progressivas de...

  9. 41 CFR 102-118.30 - Are Government corporations bound by this part?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are Government corporations bound by this part? 102-118.30 Section 102-118.30 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118...

  10. 41 CFR 102-118.5 - What is the purpose of this part?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is the purpose of this part? 102-118.5 Section 102-118.5 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  11. Development and operation of the Above Dome Inspection Rig (ADIR)

    International Nuclear Information System (INIS)

    Dickson, R.P.; Moorby, J.

    1984-01-01

    Hinkley Point 'B' is developing its remote inspection equipment in order to be able to inspect reactor internals adequately without manned vessel entry. The Above Dome Inspection Rig has been built to allow a number of inspection systems to be introduced and operated within the reactor. The ability to introduce, use and remove inspection equipment without the necessity to lift the rig from the reactor is a vital feature in the speed achieved in completing inspections quickly. Television was selected for the A.D.M. because it has significant advantages in terms of operational convenience. However the quality of image obtained in terms of information available compares unfavourably with photography. The sharpness of a photographic image is largely dictated by the chemical structure of the emulsion, whereas video is limited by the picture line structure and bandwidth. The need for a photographic system for in reactor use is therefore essential for high definition inspection requirements. The first inspection system that has been developed for the ADIR is the Telefilm camera. It consists of a Hasselblad photographic camera using an Insight television camera looking through its viewfinder. The characteristics of television and photography have been combined. (author)

  12. Unstable quantum states and rigged Hilbert spaces

    International Nuclear Information System (INIS)

    Gorini, V.; Parravicini, G.

    1978-10-01

    Rigged Hilbert space techniques are applied to the quantum mechanical treatment of unstable states in nonrelativistic scattering theory. A method is discussed which is based on representations of decay amplitudes in terms of expansions over complete sets of generalized eigenvectors of the interacting Hamiltonian, corresponding to complex eigenvalues. These expansions contain both a discrete and a continuum contribution. The former corresponds to eigenvalues located at the second sheet poles of the S matrix, and yields the exponential terms in the survival amplitude. The latter arises from generalized eigenvectors associated to complex eigenvalues on background contours in the complex plane, and gives the corrections to the exponential law. 27 references

  13. Hydraulic lifter for an underwater drilling rig

    Energy Technology Data Exchange (ETDEWEB)

    Garan' ko, Yu L

    1981-01-15

    A hydraulic lifter is suggested for an underwater drilling rig. It includes a base, hydraulic cylinders for lifting the drilling pipes connected to the clamp holder and hydraulic distributor. In order to simplify the design of the device, the base is made with a hollow chamber connected to the rod cavities and through the hydraulic distributor to the cavities of the hydraulic cylinders for lifting the drilling pipes. The hydraulic distributor is connected to the hydrosphere through the supply valve with control in time or by remote control. The base is equipped with reverse valves whose outlets are on the support surface of the base.

  14. Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation.

    Directory of Open Access Journals (Sweden)

    Qian Feng

    Full Text Available Upon viral infections, pattern recognition receptors (PRRs recognize pathogen-associated molecular patterns (PAMPs and stimulate an antiviral state associated with the production of type I interferons (IFNs and inflammatory markers. Type I IFNs play crucial roles in innate antiviral responses by inducing expression of interferon-stimulated genes and by activating components of the adaptive immune system. Although pegylated IFNs have been used to treat hepatitis B and C virus infections for decades, they exert substantial side effects that limit their use. Current efforts are directed toward the use of PRR agonists as an alternative approach to elicit host antiviral responses in a manner similar to that achieved in a natural infection. RIG-I is a cytosolic PRR that recognizes 5' triphosphate (5'ppp-containing RNA ligands. Due to its ubiquitous expression profile, induction of the RIG-I pathway provides a promising platform for the development of novel antiviral agents and vaccine adjuvants. In this study, we investigated whether structured RNA elements in the genome of coxsackievirus B3 (CVB3, a picornavirus that is recognized by MDA5 during infection, could activate RIG-I when supplied with 5'ppp. We show here that a 5'ppp-containing cloverleaf (CL RNA structure is a potent RIG-I inducer that elicits an extensive antiviral response that includes induction of classical interferon-stimulated genes, as well as type III IFNs and proinflammatory cytokines and chemokines. In addition, we show that prophylactic treatment with CVB3 CL provides protection against various viral infections including dengue virus, vesicular stomatitis virus and enterovirus 71, demonstrating the antiviral efficacy of this RNA ligand.

  15. Navigation errors encountered using weather-mapping radar for helicopter IFR guidance to oil rigs

    Science.gov (United States)

    Phillips, J. D.; Bull, J. S.; Hegarty, D. M.; Dugan, D. C.

    1980-01-01

    In 1978 a joint NASA-FAA helicopter flight test was conducted to examine the use of weather-mapping radar for IFR guidance during landing approaches to oil rig helipads. The following navigation errors were measured: total system error, radar-range error, radar-bearing error, and flight technical error. Three problem areas were identified: (1) operational problems leading to pilot blunders, (2) poor navigation to the downwind final approach point, and (3) pure homing on final approach. Analysis of these problem areas suggests improvement in the radar equipment, approach procedure, and pilot training, and gives valuable insight into the development of future navigation aids to serve the off-shore oil industry.

  16. Some Remarks on Exp-Function Method and Its Applications

    International Nuclear Information System (INIS)

    Aslan Ismail; Marinakis Vangelis

    2011-01-01

    Recently, many important nonlinear partial differential equations arising in the applied physical and mathematical sciences have been tackled by a popular approach, the so-called Exp-function method. In this paper, we present some shortcomings of this method by analyzing the results of recently published papers. We also discuss the possible improvement of the effectiveness of the method. (general)

  17. Petição para confirmação do direito do consumidor de utilização de programa de comunicações pela internet em redes sem fio e de conexão de dispositivos em tais redes

    Directory of Open Access Journals (Sweden)

    Christopher Libertelli

    2011-05-01

    Full Text Available À medida que a indústria de telecomunicações sem fio amadurece, a consolidação e o relacionamento enFtre as empresas detentoras de infraestrutura de transporte [carriers] e os produtores de aparelhos celulares [handsets] têm revelado práticas de mercado que levantam questionamentos substanciais sobre se os consumidores estariam desfrutando de todos os benefícios possíveis oriundos da competição nas telecomunicações sem fio. Por exemplo, empresas detentoras de infraestrutura de transporte de telecomunicações têm começado a influenciar agressivamente o design de programas [software] e produtos em detrimento do consumidor. Com o amadurecimento do mercado de telecomunicações sem fio e o reconhecimento de que os aparelhos celulares tornaram-se um componente indispensável para muitos americanos, empresas detentoras de infraestrutura de transporte têm utilizado de sua considerável influência sobre o uso e design destes aparelhos para manutenção do controle e dos limites ao direito dos assinantes de executar aplicativos comunicacionais de sua escolha. Ao invés de transportarem as mensagens dos assinantes independentemente do conteúdo, empresas detentoras de infraestrutura de transporte de telecomunicações têm exercido cada vez mais controle sobre a forma como os consumidores acessam a internet móvel. Ao darem preferência a serviços próprios e ao afastarem seus rivais, ditas empresas têm desabilitado ou inutilizado interfaces amigáveis ao consumidor [consumer-friendly features] em dispositivos móveis. Além disso, as empresas detentoras de infraestrutura de transporte de telecomunicações têm implementado tais práticas em violação ao princípio Carterfone da FCC e às restrições constantes da decisão da Comissão em sua formulação original referente à autorização de venda conjugada [bundling] do terminal de acesso individual e do serviço celular. A Comissão deve agir agora para fazer valer a decis

  18. Rig Technician: Apprenticeship Course Outline. Apprenticeship and Industry Training. 5211.1

    Science.gov (United States)

    Alberta Advanced Education and Technology, 2011

    2011-01-01

    The graduate of the Rig Technician apprenticeship program is a certified journeyperson who will be able to: (1) take responsibility for personal safety and the safety of others; (2) supervise, coach and train apprentices and floor hands; (3) perform the duties of a motorhand, derrickhand or driller; and (4) perform assigned tasks in accordance…

  19. 26 CFR 1.118-1 - Contributions to the capital of a corporation.

    Science.gov (United States)

    2010-04-01

    ... consideration for goods or services rendered, or to subsidies paid for the purpose of inducing the taxpayer to....118-1 Section 1.118-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Excluded from Gross Income § 1.118-1...

  20. Going deep : new generation of giant rigs extends drillers' reach

    International Nuclear Information System (INIS)

    Laverty Wilson, K.

    2001-01-01

    The Eirik Roude, an offshore super rig, arrived in Halifax Harbour from Florida in the summer 2001 for a retrofit before it is sent to work in the rugged environment offshore of Nova Scotia. The drilling platform is a joint venture between PanCanadian Petroleum and Ocean Rig. Is is the most technologically advanced and sophisticated deep water drilling platform in the world and can operate in 3,000 metre deep water for 365 days of the year. It is a fifth-generation semi-submersible rig. It floats on long legs that lower the centre of gravity below surface turbulence to provide a stable work platform even during Atlantic storms. The 110 metre long rig has three mud systems that store 593 cubic metres in mud pits, 1,260 cubic metres in pontoons, and can carry 26,140 barrels of fuel oil, 4,070 barrels of potable water and 13,210 barrels of drilling water. PanCanadian has provided $2 million to the Nova Scotia Community College to teach an appropriate curriculum for the required workforce. It is expected that 120 local workers will be recruited. PanCanadian plans to drill 3 or 4 offshore wells annually for the next 5 years. It is estimated that 700-800 workers will be on site at the peak of the retrofit. In addition, Marathon Oil has contracted the Smedvig-owned West Navion for Nova Scotia work. This vessel is designed to work in depths of up to 2,500 metres and can be upgraded to reach 3,000 metres. Its' dual handling capacity makes it suitable to do drilling and well completion simultaneously, thereby reducing the halts in operations and increasing the drilling efficiency. East Coast governments and trade associations are also committed to make the most of the offshore oil and gas revival, including the development of a petrochemical market. Their goal is to build a world class energy sector while protecting the environment and optimizing the financial, economic and social benefits to Nova Scotians. The Nova Scotia Benefits program requires that oil companies

  1. A Small Molecule that Targets r(CGG)exp and Improves Defects in Fragile X-Associated Tremor Ataxia Syndrome

    Science.gov (United States)

    Disney, Matthew D.; Liu, Biao; Yang, Wang-Yong; Sellier, Chantal; Tran, Tuan; Charlet-Berguerand, Nicolas; Childs-Disney, Jessica L.

    2012-01-01

    The development of small molecule chemical probes or therapeutics that target RNA remains a significant challenge despite the great interest in such compounds. The most significant barrier to compound development is a lack of knowledge of the chemical and RNA motif spaces that interact specifically. Herein, we describe a bioactive small molecule probe that targets expanded r(CGG) repeats, or r(CGG)exp , that causes Fragile X-associated Tremor Ataxia Syndrome (FXTAS). The compound was identified by using information on the chemotypes and RNA motifs that interact. Specifically, 9-hydroxy-5,11-dimethyl-2-(2-(piperidin-1-yl)ethyl)-6H-pyrido[4,3-b]carbazol-2-ium, binds the 5’CGG/3’GGC motifs in r(CGG)exp and disrupts a toxic r(CGG)exp -protein complex in vitro. Structure-activity relationships (SAR) studies determined that the alkylated pyridyl and phenolic side chains are important chemotypes that drive molecular recognition to r(CGG)exp . Importantly, the compound is efficacious in FXTAS model cellular systems as evidenced by its ability to improve FXTAS-associated pre-mRNA splicing defects and to reduce the size and number of r(CGG)exp -protein aggregates. This approach may establish a general strategy to identify lead ligands that target RNA while also providing a chemical probe to dissect the varied mechanisms by which r(CGG)exp promotes toxicity. PMID:22948243

  2. A generalization of resource-bounded measure, with an application (Extended abstract)

    Science.gov (United States)

    Buhrman, Harry; van Melkebeek, Dieter; Regan, Kenneth W.; Sivakumar, D.; Strauss, Martin

    We introduce resource-bounded betting games, and propose a generalization of Lutz's resource-bounded measure in which the choice of next string to bet on is fully adaptive. Lutz's martingales are equivalent to betting games constrained to bet on strings in lexicographic order. We show that if strong pseudo-random number generators exist, then betting games are equivalent to martingales, for measure on E and EXP. However, we construct betting games that succeed on certain classes whose Lutz measures are important open problems: the class of polynomial-time Turing-complete languages in EXP, and its superclass of polynomial-time Turing-autoreducible languages. If an EXP-martingale succeeds on either of these classes, or if betting games have the "finite union property" possessed by Lutz's measure, one obtains the non-relativizable consequence BPP ≠ EXP. We also show that if EXP ≠ MA, then the polynomial-time truth-table-autoreducible languages have Lutz measure zero, whereas if EXP = BPP, they have measure one.

  3. Sudden cardiac death in children (1-18 years)

    DEFF Research Database (Denmark)

    Winkel, Bo Gregers; Risgaard, Bjarke; Sadjadieh, Golnaz

    2014-01-01

    AIMS: Hitherto, sudden cardiac death in children (SCDc)-defined as sudden cardiac death (SCD) in the 1-18 years old-has been incompletely described in the general population. Knowledge on incidence rates, causes of death and symptoms prior to death is sparse and has been affected by reporting...... and referral bias. METHODS AND RESULTS: In a nationwide setting all deaths in children aged 1-18 years in Denmark in 2000-06 were included. To chart causes of death and incidence rates, death certificates and autopsy reports were collected and read. By additional use of the extensive healthcare registries...... in Denmark, we were also able to investigate prior disease and symptoms. During the 7-year study period there was an average of 1.11 million persons aged 1-18 years. There were a total of 1504 deaths (214 deaths per year) from 7.78 million person-years. A total of 114 (7.5%) were sudden and unexpected...

  4. Leucocytes DNA damage in mice exposed to JS-118 by the comet assay.

    Science.gov (United States)

    Zhang, Tao; Hu, Jiye; Zhang, Yuchao; Zhao, Qianfei; Ning, Jun

    2011-09-01

    JS-118 is an extensively used insecticide in China. The present study investigated the genotoxic effect of JS-118 on whole blood at 24, 48, 72 and 96 h by using alkaline comet assay. Male Kunming mice were given 6.25, 12.5, 25, 50 and 100 mg/kg BW of JS-118 intraperitoneally. A statistically significant increase in all comet parameters indicating DNA damage was observed at 24 h post-treatment (p JS-118 and the period of treatment. The present study provided further information of the potential risk of the genetic damage caused by JS-118.

  5. Solitary wave solutions of the fourth order Boussinesq equation through the exp(-Ф(η))-expansion method.

    Science.gov (United States)

    Akbar, M Ali; Hj Mohd Ali, Norhashidah

    2014-01-01

    The exp(-Ф(η))-expansion method is an ascending method for obtaining exact and solitary wave solutions for nonlinear evolution equations. In this article, we implement the exp(-Ф(η))-expansion method to build solitary wave solutions to the fourth order Boussinesq equation. The procedure is simple, direct and useful with the help of computer algebra. By using this method, we obtain solitary wave solutions in terms of the hyperbolic functions, the trigonometric functions and elementary functions. The results show that the exp(-Ф(η))-expansion method is straightforward and effective mathematical tool for the treatment of nonlinear evolution equations in mathematical physics and engineering. 35C07; 35C08; 35P99.

  6. Exp-function method for solving fractional partial differential equations.

    Science.gov (United States)

    Zheng, Bin

    2013-01-01

    We extend the Exp-function method to fractional partial differential equations in the sense of modified Riemann-Liouville derivative based on nonlinear fractional complex transformation. For illustrating the validity of this method, we apply it to the space-time fractional Fokas equation and the nonlinear fractional Sharma-Tasso-Olver (STO) equation. As a result, some new exact solutions for them are successfully established.

  7. Approche expérimentale de l'utilisation de glyphosate dans le ...

    African Journals Online (AJOL)

    Approche expérimentale de l'utilisation de glyphosate dans le contrôle de Melaleuca quinquenervia (Myrtaceae), une espèce envahissante dans la réserve communautaire de la forêt d'Analalava-Foulpointe (Madagascar)

  8. A drilling rig tower

    Energy Technology Data Exchange (ETDEWEB)

    Mironov, A.A.; Barashkov, V.A.; Bulgakov, E.S.; Kuldoshin, I.P.; Lebedev, A.I.; Papin, N.M.; Rebrik, B.M.; Sirotkin, N.V.

    1981-05-23

    Presentation is made of a drilling rig tower, comprising a gantry, a support shaft with a bracing strut and drawings out, and turn buckles. In order to increase the reliability of the tower in operation, to decrease the over all dimensions in a transport position, and to decrease the amount of time taken to transfer the tower from an operational position into a transportable one, and vice versa, the tower is equipped with a rotary frame made in the form of a triangular prism, whose lateral edges are connected by hinges: the first one with the lower part of the support shaft, the second with the gantry, and the third one to the upper part of the support shaft by means of the drawings out. The large boundary of the rotary frame is connected by a hinge to the support shaft by means of a bracing strut, which is equipped with a slide block connected to it by a hinge, and the rotary frame has a guide for the slide block reinforced to it on the large boundary. Besides this, the lateral edge of the rotary frame is connected to the gantry by means of turn buckles.

  9. Análise da resistência de fios cirúrgicos utilizados no reparo do manguito rotador Strength analysis of surgical sutures used to repair the rotator cuff

    Directory of Open Access Journals (Sweden)

    Marcus Valladares Guimarães

    2008-07-01

    Full Text Available OBJETIVO: Analisar a resistência final suportada por dois tipos de fio e pela interface âncora-fio em três diferentes implantes tipo âncora submetidos à tração contínua, com o propósito de indicar o mais apropriado para sutura de estruturas como o manguito rotador do ombro. MÉTODOS: Os testes foram feitos em três grupos: grupo 1 - parafuso âncora de titânio com fio Ethibond® #2; grupo 2 - parafuso âncora de titânio com fio Fiber Wire® #2; e grupo 3 - parafuso âncora de titânio 5,0mm Corkscrew®. RESULTADOS: No grupo 1, a carga máxima média até a soltura foi de 124,5 newtons (N, sendo a mínima de 105N e a máxima de 180N, com variação de 75N entre os dois extremos e desvio-padrão de 23,03N. No grupo 2, a carga máxima média até a soltura foi de 298N, mínima de 230N, máxima de 375N, com variação de 145N e desvio-padrão de 44,73N. No grupo 3, foi obtida a maior carga máxima média, sendo esta de 272N, a mínima de 205N e a máxima de 340N, com variação de 135N. A análise estatística demonstrou diferença significativa entre as médias de cargas resistidas entre os grupos 1 x 2 e 1 x 3 (p OBJECTIVE: To analyze the final strength withstood by two types of suture threads and by the anchor-suture interface in three different anchor implants submitted to continuous traction for the purpose of choosing the most appropriate to suture structures such as the shoulder rotator cuff. METHOD: Tests were performed in three groups: Group 1 - titanium anchor screw with Ethibond® #2 suture, Group 2 - titanium anchor screw with Fiber Wire® #2 suture, and Group 3 - Corkscrew® 5.0 mm anchor screw. RESULTS: In Group 1, mean maximum load till loosening was 124.5 124,5 Newtons (N, the minimum load was 105 N, and the maximum load was 180 N, with a range of 75 N between the two extremes, and standard deviation of 23.03 N. In Group 2, the mean maximum load till loosening was 298 N, the minimum load was 230 N, the maximum load was 375

  10. ExpI and PhzI are descendants of the long lost cognate signal synthase for SdiA.

    Directory of Open Access Journals (Sweden)

    Anice Sabag-Daigle

    Full Text Available SdiA of E. coli and Salmonella is a LuxR homolog that detects N-acyl homoserine lactones (AHLs. Most LuxR homologs function together with a cognate AHL synthase (a LuxI homolog, but SdiA does not. Instead, SdiA detects AHLs produced by other bacterial species. In this report, we performed a phylogenetic analysis of SdiA. The results suggest that one branch of the Enterobacteriaceae obtained a rhlR/rhlI pair by horizontal transfer. The Erwinia and Pantoea branches still contain the complete pair where it is known as expR/expI and phzR/phzI, respectively. A deletion event removed the luxI homolog from the remainder of the group, leaving just the luxR homolog known as sdiA. Thus ExpR and PhzR are SdiA orthologs and ExpI and PhzI are descendants of the long lost cognate signal synthase of SdiA.

  11. Wind tunel tests of Risoe-B1-18 and Risoe-B1-24

    Energy Technology Data Exchange (ETDEWEB)

    Fuglsang, P.; Bak, C.; Gaunaa, M.; Antoniou, I.

    2003-01-01

    This report contains 2D measurements of the Risoe-B1-18 and Risoe-B1-24 airfoils. The aerodynamic properties were derived from pressure measurements on the airfoil surface and in the wake. The measurements were conducted in the VELUX open jet wind tunnel, which has a background turbulence intensity of 1%, and an inlet flow velocity of 42 m/s. The airfoil sections had a chord of 0.600 m giving a Reynolds number of 1.6Oe106. The span was 1.9 m and end plates were used to minimize 3D flow effects. The measurements comprised both static and dynamic inflow. Static inflow covered angles of attack from 5o to 30 deg. Dynamic inflow was obtained by pitching the airfoil in a harmonic motion around various mean angles of attack. The test matrix involved smooth flow, various kinds of leading edge roughness, stall strips, vortex generators and Gurney flaps in different combinations. The quality of the measurements was good and the agreement between measurements and numerical CFD predictions with EllipSys2D was good. For both airfoils predictions with turbulent flow captured very well the shapes of lift and drag curves as well as the magnitude of maximum lift. Measurements of Risoe-B1-18 showed that the maximum lift coefficient was 1.64 at an angle of attack of approximately 13 deg. The airfoil was not very sensitive to leading edge roughness despite its high maximum lift. Measurements with stall strips showed that stall strips could control the level of maximum lift. The Risoe-B1-24 measurements showed that the maximum lift coefficient was 1.62 at an angle of attack of approximately 14 deg. The airfoil was only little sensitive to leading edge roughness despite its high relative thickness and high maximum lift. Measurements with delta wing shaped vortex generators increased the maximum lift coefficient to 2.02 and measurements with Gurney flaps increased the maximum lift coefficient to 1.85. Measurements with combination of vortex generators and Gurney flaps showed a maximum

  12. 37 CFR 1.18 - Patent post allowance (including issue) fees.

    Science.gov (United States)

    2010-07-01

    ... entity $1,190.00 (d) Publication fee $300.00. (e) For filing an application for patent term adjustment... (including issue) fees. 1.18 Section 1.18 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions Fees...

  13. Match Rigging and the Career Concerns of Referees

    DEFF Research Database (Denmark)

    Severgnini, Battista; Boeri, Tito

    2011-01-01

    This paper contributes to the literature on career concerns and corruption by drawing on extensive information on the performance of referees and records from Calciopoli, a judicial inquiry carried out in 2006 on corruption in the Italian football league. Unlike previous studies, we can analyse...... in detail the assignment of the referees to the most important matches, which is an important step in their career. Moreover, we can relate this choice to the performance of referees in previous matches and the evaluations they received in this context. We find that referees involved in match rigging were...

  14. Developmental test report, assessment of XT-70E percussion drill rig operation in tank farms

    International Nuclear Information System (INIS)

    Dougherty, L.F.

    1996-01-01

    The following report documents the testing of the XT-70E percussion drill rig for use in the 241-SX Tank Farm. The test is necessary to support evaluation of the safety and authorization level of the proposed activity of installing up to three new drywells in the 241- SX Tank Farm. The proposed activity plans to install drywells by percussion drilling 7 inch O.D./6 inch I.D. pipe in close proximity of underground storage tanks and associated equipment. The load transmitted from the drill rig's percussion hammer through the ground to the tank structure and equipment is not known and therefore testing is required to ensure the activity is safe and authorized

  15. Avaliação do coeficiente de atrito de braquetes metálicos e estéticos com fios de aço inoxidável e beta-titânio Evaluation of the friction coefficient of metal and esthetic brackets with stainless steel and beta-titanium wires

    Directory of Open Access Journals (Sweden)

    Cristine Pritsch Braga

    2004-12-01

    Full Text Available Um fator importante que define a eficácia dos aparelhos ortodônticos fixos é o atrito existente entre as superfícies de fios e braquetes. Assim, este estudo teve como objetivo investigar o coeficiente de atrito estático entre fios de aço inoxidável e beta-titânio (TP Orthodontics e braquetes de aço inoxidável (Dynalock® - Unitek, braquetes estéticos com slot de aço inoxidável (Clarity® - Unitek e estéticos convencionais (Allure® - GAC. Para tanto, construiu-se um equipamento no Departamento de Engenharia Mecânica e Mecatrônica da PUCRS. Antes de serem iniciados os testes, foi quantificado o erro de método e constatou-se que não houve interferência significante (p>0,05 do fator operador nas medições. Então, pôde-se calcular o valor do coeficiente de atrito, obtido pela divisão da força de atrito pela carga normal. O método estatístico utilizado neste estudo foi Análise de Variância (ANOVA e teste de Comparações Múltiplas (Tukey. Constatou-se que: 1 a combinação com menor coeficiente de atrito foi composta pelo fio de aço inoxidável e braquete Dynalock® e a que apresentou maior coeficiente foi a do braquete Allure® com o fio de beta-titânio; 2 o fio de beta-titânio apresentou coeficiente de atrito significativamente maior do que o fio de aço inoxidável; 3 o braquete Dynalock® não apresentou diferenças significativas em relação ao coeficiente de atrito do braquete Clarity® quando o fio utilizado foi de beta-titânio. No entanto, quando o fio testado foi de aço inoxidável, apresentou coeficiente de atrito significativamente menor. O braquete Clarity® apresentou coeficiente de atrito significativamente menor do que o braquete Allure®.An important factor that defines the effectiveness of the appliances is the friction between the surfaces of wires and brackets. Thus, that study was developed in order to investigate the static friction coefficient between stainless steel and beta-titanium wires (TP

  16. Effect of supplemental oxygen versus dobutamine administration on liver oxygen tension in dPP-guided normovolemic pigs.

    Science.gov (United States)

    Pestel, G; Fukui, K; Hager, H; Kurz, A; Hiltebrand, L

    2009-01-01

    Difference in pulse pressure (dPP) confirms adequate intravascular filling as a prerequisite for tissue perfusion. We hypothesized that both oxygen and dobutamine increase liver tissue oxygen tension (ptO(2)). Eight anesthetized pigs received dPP-guided fluid management. Hepatic pO(2) was measured with Clark-type electrodes placed subcapsularly, and on the liver surface. Pigs received: (1) supplemental oxygen (F(i)O(2) 1.0); (2) dobutamine 2.5 microg/kg/min, and (3) dobutamine 5 microg/kg/min. Data were analyzed using repeated-measures ANOVA followed by a Tukey post-test for multiple comparisons. ptO(2 )measured subcapsularly and at the liver surface were compared using the Bland-Altman plot. Variation in F(i)O(2) changed local hepatic tissue ptO(2) [subcapsular measurement: 39 +/- 12 (F(i)O(2) 0.3), 89 +/- 35 mm Hg (F(i)O(2) 1.0, p = 0.01 vs. F(i)O(2) 0.3), 44 +/- 10 mm Hg (F(i)O(2) 0.3, p = 0.05 vs. F(i)O(2) 1.0); surface measurement: 52 +/- 35 (F(i)O(2) 0.3), 112 +/- 24 mm Hg (F(i)O(2) 1.0, p = 0.001 vs. F(i)O(2) 0.3), 54 +/- 24 mm Hg (F(i)O(2) 0.3, p = 0.001 vs. F(i)O(2) 1.0)]. Surface measurements were widely scattered compared to subcapsular measurements (bias: -15 mm Hg, precision: 76.3 mm Hg). Dobutamine did not affect hepatic oxygenation. Supplemental oxygen increased hepatic tissue pO(2) while dobutamine did not. Although less invasive, the use of surface measurements is discouraged. Copyright 2009 S. Karger AG, Basel.

  17. Overexpression of the transcription factor Sp1 activates the OAS-RNAse L-RIG-I pathway.

    Directory of Open Access Journals (Sweden)

    Valéryane Dupuis-Maurin

    Full Text Available Deregulated expression of oncogenes or transcription factors such as specificity protein 1 (Sp1 is observed in many human cancers and plays a role in tumor maintenance. Paradoxically in untransformed cells, Sp1 overexpression induces late apoptosis but the early intrinsic response is poorly characterized. In the present work, we studied increased Sp1 level consequences in untransformed cells and showed that it turns on an early innate immune transcriptome. Sp1 overexpression does not activate known cellular stress pathways such as DNA damage response or endoplasmic reticulum stress, but induces the activation of the OAS-RNase L pathway and the generation of small self-RNAs, leading to the upregulation of genes of the antiviral RIG-I pathway at the transcriptional and translational levels. Finally, Sp1-induced intrinsic innate immune response leads to the production of the chemokine CXCL4 and to the recruitment of inflammatory cells in vitro and in vivo. Altogether our results showed that increased Sp1 level in untransformed cells constitutes a novel danger signal sensed by the OAS-RNase L axis leading to the activation of the RIG-I pathway. These results suggested that the OAS-RNase L-RIG-I pathway may be activated in sterile condition in absence of pathogen.

  18. Experimental investigation of decay properties of neutron deficient $^{116-118}$Ba isotopes and test of $^{112-115}$Ba beam counts

    CERN Multimedia

    We propose to study decay of neutron deficient isotopes $^{116-118}$Ba using Double Sided Silicon Strip Detector (DSSSD). To study delayed-proton and $\\alpha$-decay branching ratios of $^{116-118}$Ba are of special interest because of their vicinity to the proton drip line. The nuclear life-times and properties of the proton unstable states of Cs isotopes, populated through decay of $^{116-118}$Ba isotopes will be measured. In addition to that we propose beam development of $^{112-115}$Ba to study exotic decay properties of these neutron deficient nuclei and to search for super-allowed $\\alpha$-decay in future.

  19. Estudo de propriedades dinâmico-mecânicas de um compósito aeronáutico de CFRP com fios de ligas com memória de forma embebidos

    Directory of Open Access Journals (Sweden)

    Zoroastro Torres Vilar

    2016-01-01

    Full Text Available Resumo Este trabalho trata-se de um estudo experimental do comportamento de propriedades termomecânicas de um compósito ativo, obtido através da introdução de diferentes frações volumétricas de fios de uma liga NiTi com efeito de memoria de forma em uma matriz polimérica reforçada com fibras de carbono (CFRP. Para tal estudo, inicialmente fez-se uma análise do módulo elástico de um pré preg de CFRP aeronáutico com diferentes posições de ângulo de fibras de carbono, a fim de determinar a matriz mais adequada para a introdução de fios de NiTi para obter compósito ativo. Verificou-se que a matriz com fibras alinhadas a 15º apresenta-se como uma boa opção para a obtenção de compósitos ativos, sendo utilizada para a fabricação de amostras de CFRP/NiTi. As amostras tiveram seu potencial de ativação avaliado através da análise da variação do módulo de elasticidade com o aumento da temperatura usando a técnica de Análise Dinâmico-Mecânica (DMA. Através dos resultados obtidos, verificou-se a capacidade de ativação dos compósitos CFRP/NiTi, os quais apresentam variação positiva de módulo de elasticidade ao serem aquecidos acima da temperatura de transformação dos fios NiTi.

  20. Ergonomic exposure on a drilling rig

    DEFF Research Database (Denmark)

    Jensen, Carsten; Jensen, Chris

    . In a relatively old study on American drilling rigs it was indicated that lower back problems was a frequent cause of absence (Clemmer et al. 1991). Most of the incidents causing lower back injuries were associated with heavy lifting or pushing/pulling objects by roustabouts, floorhands, derrickmen and welders......, but for some of the most frequent problems, such as musculoskeletal problems, it is difficult to determine whether the causes are work‐related or not. As manual handling (lifting, pushing, etc.) in awkward body postures increase the risk of developing musculoskeletal disorders, it should be expected that work......‐related health problems contribute to sickness absence in the offshore industry, if these working postures are common. However, also work‐related psychosocial factors, personal factors and other factors may contribute to the development of lower back disorders, which often have a multifactorial background...

  1. Design review and analysis for a Pratt and Whitney fluid-film bearing and seal testing rig

    Science.gov (United States)

    Childs, Dara W.

    1994-01-01

    A design review has been completed for a Pratt and Whitney (P&W)-designed fluid-film bearing and annular-seal test rig to be manufactured and installed at George C. Marshall Space Flight Center (MSFC). Issues covered in this study include: (1) the capacity requirements of the drive unit; (2) the capacity and configuration of the static loading system; (3) the capacity and configuration of the dynamic excitation system; (4) the capacity, configuration, and rotordynamic stability of a test bearing, support bearings, and shaft; and (5) the characteristics and configuration of the measurement transducers and data channels.

  2. New application of Exp-function method for improved Boussinesq equation

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.A. [Theoretical Research Group, Physics Department, Faculty of Science, Mansoura University, 35516 Mansoura (Egypt); Department of Physics, Faculty of Education for Girls, Science Departments, King Khalid University, Bisha (Saudi Arabia)], E-mail: m_abdou_eg@yahoo.com; Soliman, A.A. [Department of Mathematics, Faculty of Education (AL-Arish) Suez Canal University, AL-Arish 45111 (Egypt); Department of Mathematics, Teacher' s College (Bisha), King Khalid University, Bisha, PO Box 551 (Saudi Arabia)], E-mail: asoliman_99@yahoo.com; El-Basyony, S.T. [Theoretical Research Group, Physics Department, Faculty of Science, Mansoura University, 35516 Mansoura (Egypt)

    2007-10-01

    The Exp-function method is used to obtain generalized solitary solutions and periodic solutions for nonlinear evolution equations arising in mathematical physics with the aid of symbolic computation method, namely, the improved Boussinesq equation. The method is straightforward and concise, and its applications is promising for other nonlinear evolution equations in mathematical physics.

  3. Assessment of volume and leak measurements during CPAP using a neonatal lung model.

    Science.gov (United States)

    Fischer, H S; Roehr, C C; Proquitté, H; Wauer, R R; Schmalisch, G

    2008-01-01

    Although several commercial devices are available which allow tidal volume and air leak monitoring during continuous positive airway pressure (CPAP) in neonates, little is known about their measurement accuracy and about the influence of air leaks on volume measurement. The aim of this in vitro study was the validation of volume and leak measurement under CPAP using a commercial ventilatory device, taking into consideration the clinical conditions in neonatology. The measurement accuracy of the Leoni ventilator (Heinen & Löwenstein, Germany) was investigated both in a leak-free system and with leaks simulated using calibration syringes (2-10 ml, 20-100 ml) and a mechanical lung model. Open tubes of variable lengths were connected for leak simulation. Leak flow was measured with the flow-through technique. In a leak-free system the mean relative volume error +/-SD was 3.5 +/- 2.6% (2-10 ml) and 5.9 +/- 0.7% (20-60 ml), respectively. The influence of CPAP level, driving flow, respiratory rate and humidification of the breathing gas on the volume error was negligible. However, an increasing F(i)O(2) caused the measured tidal volume to increase by up to 25% (F(i)O(2) = 1.0). The relative error +/- SD of the leak measurements was -0.2 +/- 11.9%. For leaks > 19%, measured tidal volume was underestimated by more than 10%. In conclusion, the present in vitro study showed that the Leoni allowed accurate volume monitoring under CPAP conditions similar to neonates. Air leaks of up to 90% of patient flow were reliably detected. For an F(i)O(2) > 0.4 and for leaks > 19%, a numerical correction of the displayed volume should be performed.

  4. 118-C-4 Horizontal Rod Cave Characterization Report

    International Nuclear Information System (INIS)

    Encke, B.D.; Thoren, R.A.

    1998-03-01

    This report addresses the characterization data collected from 118-C- 4 Horizontal Rod Cave in December 1996 and August 1997. The characterization activities evaluated the radiological status and identified hazardous materials locations. The scope of this report is limited to the 118-C-4 Facility Structure. Information in this report can be used to identify the waste streams, provide specific chemical and radiological data to aid in planning decontamination and decommissioning (D ampersand D) activities, and allow proper disposal of the demolition debris, as required by the Comprehensive Environmental Response, Compensation, and Liability Act of 1980

  5. A Thrust Allocation Method for Efficient Dynamic Positioning of a Semisubmersible Drilling Rig Based on the Hybrid Optimization Algorithm

    Directory of Open Access Journals (Sweden)

    Luman Zhao

    2015-01-01

    Full Text Available A thrust allocation method was proposed based on a hybrid optimization algorithm to efficiently and dynamically position a semisubmersible drilling rig. That is, the thrust allocation was optimized to produce the generalized forces and moment required while at the same time minimizing the total power consumption under the premise that forbidden zones should be taken into account. An optimization problem was mathematically formulated to provide the optimal thrust allocation by introducing the corresponding design variables, objective function, and constraints. A hybrid optimization algorithm consisting of a genetic algorithm and a sequential quadratic programming (SQP algorithm was selected and used to solve this problem. The proposed method was evaluated by applying it to a thrust allocation problem for a semisubmersible drilling rig. The results indicate that the proposed method can be used as part of a cost-effective strategy for thrust allocation of the rig.

  6. Advisory expert system for test rig operator

    International Nuclear Information System (INIS)

    Zielczynski, P.

    1994-01-01

    The advisory expert system MAESTRO (Modular Advisory Expert System for Test Rig Operator) has been designed to guide the operator of large experimental installation during start-up, steady state and shut down. The installation is located in the research reactor MARIA in the Institute of Atomic Energy in Swierk, Poland. The system acquires and analyses on line signals from installation and performs two tasks in real time: leading the operator and monitoring of the installation (including signal validation). Systems tasks, architecture and knowledge representation concepts are described. The system is based on expert systems techniques what makes in phases of continuous change of process parameters and it has been achieved by special knowledge representation allowing its dynamical modification. (author). 147 refs, 42 figs, 5 tab

  7. Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota.

    Directory of Open Access Journals (Sweden)

    Eliette Riboulet-Bisson

    Full Text Available Lactobacilli are gram-positive bacteria that are a subdominant element in the human gastrointestinal microbiota, and which are commonly used in the food industry. Some lactobacilli are considered probiotic, and have been associated with health benefits. However, there is very little culture-independent information on how consumed probiotic microorganisms might affect the entire intestinal microbiota. We therefore studied the impact of the administration of Lactobacillus salivarius UCC118, a microorganism well characterized for its probiotic properties, on the composition of the intestinal microbiota in two model animals. UCC118 has anti-infective activity due to production of the bacteriocin Abp118, a broad-spectrum class IIb bacteriocin, which we hypothesized could impact the microbiota. Mice and pigs were administered wild-type (WT L. salivarius UCC118 cells, or a mutant lacking bacteriocin production. The microbiota composition was determined by pyrosequencing of 16S rRNA gene amplicons from faeces. The data show that L. salivarius UCC118 administration had no significant effect on proportions of major phyla comprising the mouse microbiota, whether the strain was producing bacteriocin or not. However, L. salivarius UCC118 WT administration led to a significant decrease in Spirochaetes levels, the third major phylum in the untreated pig microbiota. In both pigs and mice, L. salivarius UCC118 administration had an effect on Firmicutes genus members. This effect was not observed when the mutant strain was administered, and was thus associated with bacteriocin production. Surprisingly, in both models, L. salivarius UCC118 administration and production of Abp118 had an effect on gram-negative microorganisms, even though Abp118 is normally not active in vitro against this group of microorganisms. Thus L. salivarius UCC118 administration has a significant but subtle impact on mouse and pig microbiota, by a mechanism that seems at least partially

  8. Mechanical Design of a Performance Test Rig for the Turbine Air-Flow Task (TAFT)

    Science.gov (United States)

    Forbes, John C.; Xenofos, George D.; Farrow, John L.; Tyler, Tom; Williams, Robert; Sargent, Scott; Moharos, Jozsef

    2004-01-01

    To support development of the Boeing-Rocketdyne RS84 rocket engine, a full-flow, reaction turbine geometry was integrated into the NASA-MSFC turbine air-flow test facility. A mechanical design was generated which minimized the amount of new hardware while incorporating all test and instrumentation requirements. This paper provides details of the mechanical design for this Turbine Air-Flow Task (TAFT) test rig. The mechanical design process utilized for this task included the following basic stages: Conceptual Design. Preliminary Design. Detailed Design. Baseline of Design (including Configuration Control and Drawing Revision). Fabrication. Assembly. During the design process, many lessons were learned that should benefit future test rig design projects. Of primary importance are well-defined requirements early in the design process, a thorough detailed design package, and effective communication with both the customer and the fabrication contractors.

  9. Practical calibration of design data to technical capabilities of horizontal directional drilling rig

    Science.gov (United States)

    Toropov, S. Yu; Toropov, V. S.

    2018-05-01

    In order to design more accurately trenchless pipeline passages, a technique has been developed for calculating the passage profile, based on specific parameters of the horizontal directional drilling rig, including the range of possible drilling angles and a list of compatible drill pipe sets. The algorithm for calculating the parameters of the trenchless passage profile is shown in the paper. This algorithm is based on taking into account the features of HDD technology, namely, three different stages of production. The authors take into account that the passage profile is formed at the first stage of passage construction, that is, when drilling a pilot well. The algorithm involves calculating the profile by taking into account parameters of the drill pipes used and angles of their deviation relative to each other during the pilot drilling. This approach allows us to unambiguously calibrate the designed profile for the HDD rig capabilities and the auxiliary and navigation equipment used in the construction process.

  10. Coherent anti-Stokes Raman scattering for quantitative temperature and concentration measurements in a high-pressure gas turbine combustor rig

    Science.gov (United States)

    Thariyan, Mathew Paul

    Dual-pump coherent anti-Stokes Raman scattering (DP-CARS) temperature and major species (CO2/N2) concentration measurements have been performed in an optically-accessible high-pressure gas turbine combustor facility (GTCF) and for partially-premixed and non-premixed flames in a laminar counter-flow burner. A window assembly incorporating pairs of thin and thick fused silica windows on three sides was designed, fabricated, and assembled in the GTCF for advanced laser diagnostic studies. An injection-seeded optical parametric oscillator (OPO) was used as a narrowband pump laser source in the dual-pump CARS system. Large prisms on computer-controlled translation stages were used to direct the CARS beams either into the main optics leg for measurements in the GTCF or to a reference optics leg for measurements of the nonresonant CARS spectrum and for aligning the CARS system. Combusting flows were stabilized with liquid fuel injection only for the central injector of a 9-element lean direct injection (LDI) device developed at NASA Glenn Research Center. The combustor was operated using Jet A fuel at inlet air temperatures up to 725 K and combustor pressures up to 1.03 MPa. Single-shot DP-CARS spectra were analyzed using the Sandia CARSFT code in the batch operation mode to yield instantaneous temperature and CO2/N2 concentration ratio values. Spatial maps of mean and standard deviations of temperature and CO2/N2 concentrations were obtained in the high-pressure LDI flames by translating the CARS probe volume in axial and vertical directions inside the combustor rig. The mean temperature fields demonstrate the effect of the combustor conditions on the overall flame length and the average flame structure. The temperature relative standard deviation values indicate thermal fluctuations due to the presence of recirculation zones and/or flame brush fluctuations. The correlation between the temperature and relative CO 2 concentration data has been studied at various combustor

  11. Design of Seismic Test Rig for Control Rod Drive Mechanism of Jordan Research and Training Reactor

    International Nuclear Information System (INIS)

    Sun, Jongoh; Kim, Gyeongho; Yoo, Yeonsik; Cho, Yeonggarp; Kim, Jong In

    2014-01-01

    The reactor assembly is submerged in a reactor pool filled with water and its reactivity is controlled by locations of four control absorber rods(CARs) inside the reactor assembly. Each CAR is driven by a stepping motor installed at the top of the reactor pool and they are connected to each other by a tie rod and an electromagnet. The CARs scram the reactor by de-energizing the electromagnet in the event of a safe shutdown earthquake(SSE). Therefore, the safety function of the control rod drive mechanism(CRDM) which consists of a drive assembly, tie rod and CARs is to drop the CAR into the core within an appropriate time in case of the SSE. As well known, the operability for complex equipment such as the CRDM during an earthquake is very hard to be demonstrated by analysis and should be verified through tests. One of them simulates the reactor assembly and the guide tube of the CAR, and the other one does the pool wall where the drive assembly is installed. In this paper, design of the latter test rig and how the test is performed are presented. Initial design of the seismic test rig and excitation table had its first natural frequency at 16.3Hz and could not represent the environment where the CRDM was installed. Therefore, experimental modal analyses were performed and an FE model for the test rig and table was obtained and tuned based on the experimental results. Using the FE model, the design of the test rig and table was modified in order to have higher natural frequency than the cutoff frequency. The goal was achieved by changing its center of gravity and the stiffness of its sliding bearings

  12. Design of Seismic Test Rig for Control Rod Drive Mechanism of Jordan Research and Training Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Jongoh; Kim, Gyeongho; Yoo, Yeonsik; Cho, Yeonggarp; Kim, Jong In [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The reactor assembly is submerged in a reactor pool filled with water and its reactivity is controlled by locations of four control absorber rods(CARs) inside the reactor assembly. Each CAR is driven by a stepping motor installed at the top of the reactor pool and they are connected to each other by a tie rod and an electromagnet. The CARs scram the reactor by de-energizing the electromagnet in the event of a safe shutdown earthquake(SSE). Therefore, the safety function of the control rod drive mechanism(CRDM) which consists of a drive assembly, tie rod and CARs is to drop the CAR into the core within an appropriate time in case of the SSE. As well known, the operability for complex equipment such as the CRDM during an earthquake is very hard to be demonstrated by analysis and should be verified through tests. One of them simulates the reactor assembly and the guide tube of the CAR, and the other one does the pool wall where the drive assembly is installed. In this paper, design of the latter test rig and how the test is performed are presented. Initial design of the seismic test rig and excitation table had its first natural frequency at 16.3Hz and could not represent the environment where the CRDM was installed. Therefore, experimental modal analyses were performed and an FE model for the test rig and table was obtained and tuned based on the experimental results. Using the FE model, the design of the test rig and table was modified in order to have higher natural frequency than the cutoff frequency. The goal was achieved by changing its center of gravity and the stiffness of its sliding bearings.

  13. Development of high temperature mechanical rig for characterizing the viscoplastic properties of alloys used in solid oxide cells

    DEFF Research Database (Denmark)

    Tadesse Molla, Tesfaye; Greco, Fabio; Kwok, Kawai

    2018-01-01

    Analyzing the thermo-mechanical reliability of solid oxide cell (SOC) stack requires precise measurement of the mechanical properties of the different components in the stack at operating conditions of the SOC. It is challenging to precisely characterize the time dependent deformational properties...... temperature and in controlled atmosphere. The methodology uses a mechanical loading rig designed to apply variable as well as constant loads on samples within a gas-tight high temperature furnace. In addition, a unique remotely installed length measuring setup involving laser micrometer is used to monitor...... deformations in the sample. Application of the methodology is exemplified by measurement of stress relaxation, creep and constant strain rate behaviors of a high temperature alloy used in the construction of SOC metallic interconnects at different temperatures. Furthermore, measurements using the proposed...

  14. 40 CFR 93.118 - Criteria and procedures: Motor vehicle emissions budget.

    Science.gov (United States)

    2010-07-01

    ... emissions budget. 93.118 Section 93.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... and procedures: Motor vehicle emissions budget. (a) The transportation plan, TIP, and project not from a conforming transportation plan and TIP must be consistent with the motor vehicle emissions budget...

  15. Analysis and modification of a single-mesh gear fatigue rig for use in diagnostic studies

    Science.gov (United States)

    Zakrajsek, James J.; Townsend, Dennis P.; Oswald, Fred B.; Decker, Harry J.

    1992-01-01

    A single-mesh gear fatigue rig was analyzed and modified for use in gear mesh diagnostic research. The fatigue rig allowed unwanted vibration to mask the test-gear vibration signal, making it difficult to perform diagnostic studies. Several possible sources and factors contributing to the unwanted components of the vibration signal were investigated. Sensor mounting location was found to have a major effect on the content of the vibration signal. In the presence of unwanted vibration sources, modal amplification made unwanted components strong. A sensor location was found that provided a flatter frequency response. This resulted in a more useful vibration signal. A major network was performed on the fatigue rig to reduce the influence of the most probable sources of the noise in the vibration signal. The slave gears were machined to reduce weight and increase tooth loading. The housing and the shafts were modified to reduce imbalance, looseness, and misalignment in the rotating components. These changes resulted in an improved vibration signal, with the test-gear mesh frequency now the dominant component in the signal. Also, with the unwanted sources eliminated, the sensor mounting location giving the most robust representation of the test-gear meshing energy was found to be at a point close to the test gears in the load zone of the bearings.

  16. Computational Analysis of a South African Mobile Trailer-Type Medium Sized Tyre Test Rig

    CSIR Research Space (South Africa)

    Sharma, Shikar

    2015-04-01

    Full Text Available To support the South African National Defence Force with their vehicle mobility needs, the CSIR has begun characterising tyres by using a medium, trailer-type, tyre test rig. Two different Pacejka tyre models were generated using two independent...

  17. 77 FR 23117 - Rigging Equipment for Material Handling Construction Standard; Correction and Technical Amendment

    Science.gov (United States)

    2012-04-18

    ... Equipment for Material Handling Construction Standard; Correction and Technical Amendment AGENCY... AND HEALTH REGULATIONS FOR CONSTRUCTION Subpart H--Materials Handling, Storage, Use, and Disposal 0 1... amendment. SUMMARY: OSHA is correcting its sling standard for construction titled ``Rigging Equipment for...

  18. Fall protection training for rig workers : are your rig workers up to standard in fall risks and how to avoid them?

    Energy Technology Data Exchange (ETDEWEB)

    Chausse, C.

    2010-07-15

    This article offered advice on how to train rig workers in fall protection procedures. Any employee who works at height must complete fall protection training, which should be both in-classroom and hands-on, and site conditions must be closely simulated. There are three basic levels of training. A supervisor can identify hazards and has the authorization to take prompt corrective measures to ensure that all employees working at height are trained and using fall protection procedures. Any team leader should be trained as a competent person, who can conduct fall hazard surveys, identify new and existing fall hazards, and determine how to protect employees from each hazard. A qualified person is one who by certification or experience has successfully demonstrated an ability to resolve problems. The basic level of training ensures that a worker can recognize and control hazards, understand government fall regulations, follow post-fall rescue procedures, and select suitable rescue equipment. Supervisors may be trained as competent or qualified persons and should have knowledge of fall protection regulations, standards, and the equipment and systems being used in the workplace. Constant reminders at safety talks and refresher training are integral to maintaining a high degree of safety consciousness. 3 figs.

  19. Exp-function method for solving Fisher's equation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, X-W [Department of Mathematics, Kunming Teacher' s College, Kunming, Yunnan 650031 (China)], E-mail: km_xwzhou@163.com

    2008-02-15

    There are many methods to solve Fisher's equation, but each method can only lead to a special solution. In this paper, a new method, namely the exp-function method, is employed to solve the Fisher's equation. The obtained result includes all solutions in open literature as special cases, and the generalized solution with some free parameters might imply some fascinating meanings hidden in the Fisher's equation.

  20. An Extended IEEE 118-Bus Test System With High Renewable Penetration

    Energy Technology Data Exchange (ETDEWEB)

    Pena, Ivonne; Martinez-Anido, Carlo Brancucci; Hodge, Bri-Mathias

    2018-01-01

    This article describes a new publicly available version of the IEEE 118-bus test system, named NREL-118. The database is based on the transmission representation (buses and lines) of the IEEE 118-bus test system, with a reconfigured generation representation using three regions of the US Western Interconnection from the latest Western Electricity Coordination Council (WECC) 2024 Common Case [1]. Time-synchronous hourly load, wind, and solar time series are provided for over one year (8784 hours). The public database presented and described in this manuscript will allow researchers to model a test power system using detailed transmission, generation, load, wind, and solar data. This database includes key additional features that add to the current IEEE 118-bus test model, such as: the inclusion of 10 generation technologies with different heat rate functions, minimum stable levels and ramping rates, GHG emissions rates, regulation and contingency reserves, and hourly time series data for one full year for load, wind and solar generation.

  1. 27 Etude comparative de la compacité expérimentale et ...

    African Journals Online (AJOL)

    Moussa

    objectif de notre recherche ... Par définition la compacité virtuelle est inaccessible à l'expérience et à partir de la formule (1) on remarque .... l'optimisation granulaire par des modèles théoriques constitue un bon outil d'étude des empilements.

  2. Investigating Knowledge Transfer Mechanisms for Oil Rigs

    DEFF Research Database (Denmark)

    Vianello, Giovanna; Ahmed, Saeema

    2009-01-01

    It is widely recognized, both in industry and academia, that clear strategies in knowledge transfer positively influence the success of a firm. A firm should support the transfer of knowledge by standardizing communication channels within and across departments, based upon personalization......, codification or a combination of these two strategies. The characteristics of the business influence the choice of communication channels used for knowledge transfer. This paper presents a case study exploring the transfer of knowledge within and across projects, specifically the transfer of service knowledge...... in the case of complex machinery. The strategies used for knowledge transfer were analysed and compared with the expected transfer mechanisms, similarities and differences were investigated and are described. A family of four identical rigs for offshore drilling was the selected case. The transfer...

  3. Espaces virtuels et pré-expérience de l’espace géographique

    Directory of Open Access Journals (Sweden)

    Jérémie Valentin

    2013-05-01

    Full Text Available Les représentations virtuelles de l’espace se sont largement démocratisées lors des dernières années. La libéralisation du marché des images satellites et l’augmentation des capacités de transfert de données sur les réseaux filaires et non filaires participent largement à la mise en place de mondes miroirs désormais connectés au cyberespace.L’homme a de plus en plus recours aux espaces virtuels pour appréhender l’espace. Que ce soit pour l’élaboration d’un itinéraire ou la découverte d’un lieu, la carte papier et le guide touristique s’effacent au profit du monde miroir et du téléphone portable.Dans ce contexte de transfert d’usage, les représentations virtuelles de l’espace semblent, au même titre que l’usage des GPS, offrir une perception biaisée de l’espace. Car malgré leurs qualités intrinsèques communes, en particulier pour la navigation dans un espace inconnu, leurs usages modifieraient notre relation à l’espace et pourraient dans certains cas altérer son apprentissage. L’objectif de cette communication pluridisciplinaire est de mettre au jour la popularité des mondes miroirs tout en interrogeant leurs usages en condition de pré-expérience de l’espace, car les dispositifs actuels permettent d’expérimenter virtuellement l’espace avant d’en faire physiquement l’expérience. Nous verrons à travers une expérience comparative, que dans le cadre d’un parcours complexe, les sujets ayant eu une pré-expérience virtuelle de l’espace s’avèrent moins efficaces que les sujets qui ont consulté un plan papier 2D et moins efficaces que les sujets ayant effectué une visite guidée. L’analyse des traces GPS des sujets nous permettra de tirer des conclusions sur les typologies d’échecs et d’erreurs.

  4. New Traveling Wave Solutions of the Higher Dimensional Nonlinear Partial Differential Equation by the Exp-Function Method

    Directory of Open Access Journals (Sweden)

    Hasibun Naher

    2012-01-01

    Full Text Available We construct new analytical solutions of the (3+1-dimensional modified KdV-Zakharov-Kuznetsev equation by the Exp-function method. Plentiful exact traveling wave solutions with arbitrary parameters are effectively obtained by the method. The obtained results show that the Exp-function method is effective and straightforward mathematical tool for searching analytical solutions with arbitrary parameters of higher-dimensional nonlinear partial differential equation.

  5. Soluções de redução de consumo energético para redes de sensores sem fio (RSSFs aplicadas à ambientes florestais

    Directory of Open Access Journals (Sweden)

    Paulo César Sedrez Moncks

    2016-07-01

    Full Text Available Redes de sensores sem fio (RSSFs têm sido utilizadas para aplicações de monitoramento nos mais diversos cenários, como controle industrial, gerenciamento de tráfego, segurança pública, automação residencial, saúde e também monitoramento ambiental. Estas redes são compostas de sensores com restrição de recursos onde a eficiência energética é parte essencial para sua real aplicabilidade. É apresentada neste artigo a sistematização feita das características de três técnicas para redução do consumo energético das redes de sensores sem fio, e como principal objetivo desta sistematização espera-se fornecer elementos para avaliar a aplicabilidade de RSSFs nas tarefas de predição de risco e monitoramento de incêndios florestais. Foi possível concluir que o uso de RSSFs aplicadas a ambientes florestais ainda é uma frente de pesquisa em aberto, sobretudo no que se refere à durabilidade da vida útil da rede. Ainda que as técnicas de redução de consumo energético propostas nos trabalhos avaliados apresentem ganhos, é necessário aprofundar as pesquisas para alcançar um tempo maior de duração das baterias e com isso tornar viável a instalação de nodos em florestas.

  6. Comment on “Temperature dependence of atomic vibrations in mono-layer graphene” [J. Appl. Phys. 118, 074302 (2015)

    International Nuclear Information System (INIS)

    Susi, T.; Kotakoski, J.

    2016-01-01

    In an interesting recent study [Allen et al., J. Appl. Phys. 118, 074302 (2015)] (see also their Erratum [Allen et al., J. Appl. Phys. 118, 159902 (2015)]), Allen and co-workers measured the mean square amplitudes of graphene lattice vibrations between 100 and 1300 K and used a simplified theoretical approximation for the acoustic phonon modes to evaluate the maximum phonon wavelengths supported by the lattice. By fitting their data using the smallest wave-vector as the fitting parameter, they found this to be significantly smaller than the physical size of the graphene crystallites

  7. Evidence of parity violation in 118Sn and 36Cl

    International Nuclear Information System (INIS)

    Benkoula, H.

    1978-01-01

    Parity violation in nuclear systems was studied by forward-backward asymmetry measurement methods in radiative capture of polarized neutrons in the reactions 117 Sn(n,γ) 118 Sn and 35 Cl(n,γ) 36 Cl. The experimental set ups used two INa detectors situated at left and right sides of the beam and parallel to polarisation direction, and an electronic system adapted to high-counting rate. The asymmetry measurement, A=(4.56+-0.6)x10 -4 in the 9.328 MeV Ml transition demonstrates the existence of parity violation effects. The 8.58 MeV (M1+E2) transition in 36 Cl was also studied and the asymmetry value is A=(1.11+-0.35)x10 -4 . Several beam and electronic tests have shown that there was no spurious asymmetry in the measurement due to the equipment [fr

  8. 7 CFR 1221.118 - Refund escrow accounts.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... INFORMATION ORDER Sorghum Promotion, Research, and Information Order Sorghum Promotion, Research, and Information Board § 1221.118 Refund escrow accounts. (a) The Board shall establish an interest bearing escrow...

  9. High-temperature rate constant measurements for OH+xylenes

    KAUST Repository

    Elwardani, Ahmed Elsaid

    2015-06-01

    The overall rate constants for the reactions of hydroxyl (OH) radicals with o-xylene (k 1), m-xylene (k 2), and p-xylene (k 3) were measured behind reflected shock waves over 890-1406K at pressures of 1.3-1.8atm using OH laser absorption near 306.7nm. Measurements were performed under pseudo-first-order conditions. The measured rate constants, inferred using a mechanism-fitting approach, can be expressed in Arrhenius form as:k1=2.93×1013exp(-1350.3/T)cm3mol-1s-1(890-1406K)k2=3.49×1013exp(-1449.3/T)cm3mol-1s-1(906-1391K)k3=3.5×1013exp(-1407.5/T)cm3mol-1s-1(908-1383K)This paper presents, to our knowledge, first high-temperature measurements of the rate constants of the reactions of xylene isomers with OH radicals. Low-temperature rate-constant measurements by Nicovich et al. (1981) were combined with the measurements in this study to obtain the following Arrhenius expressions, which are applicable over a wider temperature range:k1=2.64×1013exp(-1181.5/T)cm3mol-1s-1(508-1406K)k2=3.05×109exp(-400/T)cm3mol-1s-1(508-1391K)k3=3.0×109exp(-440/T)cm3mol-1s-1(526-1383K) © 2015 The Combustion Institute.

  10. 41 CFR 102-118.60 - To what extent must my agency use electronic commerce?

    Science.gov (United States)

    2010-07-01

    ... agency use electronic commerce? 102-118.60 Section 102-118.60 Public Contracts and Property Management... Services § 102-118.60 To what extent must my agency use electronic commerce? Your agency must use electronic commerce in all areas of your transportation program. This includes the use of electronic systems...

  11. A durability test rig and methodology for erosion-resistant blade coatings in turbomachinery

    Science.gov (United States)

    Leithead, Sean Gregory

    A durability test rig for erosion-resistant gas turbine engine compressor blade coatings was designed, completed and commissioned. Bare and coated 17-4PH steel V103-profile blades were rotated at up to 11500 rpm and impacted with Garnet sand for 5 hours at an average concentration of 2.51 gm3of air , at a blade leading edge Mach number of 0.50. The rig was determined to be an acceptable first stage axial compressor representation. Two types of 16 microm-thick coatings were tested: Titanium Nitride (TiN) and Chromium-Aluminum-Titanium Nitride (CrAlTiN), both applied using an Arc Physical Vapour Deposition technique at the National Research Council in Ottawa, Canada. A Leithead-Allan-Zhao (LAZ) score was created to compare the durability performance of uncoated and coated blades based on mass-loss and blade dimension changes. The bare blades' LAZ score was set as a benchmark of 1.00. The TiN-coated and CrAlTiN-coated blades obtained LAZ scores of 0.69 and 0.41, respectively. A lower score meant a more erosion-resistant coating. Major modes of blade wear included: trailing edge, leading edge and the rear suction surface. Trailing edge thickness was reduced, the leading edge became blunt, and the rear suction surface was scrubbed by overtip and recirculation zone vortices. It was found that the erosion effects of vortex flow were significant. Erosion damage due to reflected particles was not present due to the low blade solidity of 0.7. The rig is best suited for studying the performance of erosion-resistant coatings after they are proven effective in ASTM standardized testing. Keywords: erosion, compressor, coatings, turbomachinery, erosion rate, blade, experimental, gas turbine engine

  12. Control of two-phase erosion corrosion with the amine 5-aminopentanol: rig and plant trials

    International Nuclear Information System (INIS)

    Lewis, G.G.; Greene, J.C.; Tyldesley, J.D.; Wetton, E.A.M.; Fountain, M.J.

    1994-01-01

    Control of two-phase erosion corrosion in the once through mild steel boilers of the gas cooled nuclear power station at Wylfa was achieved by using the amine 2-amino, 2 methylpropan-1-ol (AMP). In a search to find a more cost effective amine, 5-aminopentanol (5-AP) emerged, from a laboratory based programme to determine basicity and volatility, as the most promising candidate. The effectiveness of 5-AP in controlling erosion corrosion was demonstrated in a rig test, carried out on a full scale replica of a Wylfa boiler tube. Following on from the rig test, a plant trial at Wylfa PS demonstrated 5-AP's superior thermal stability (compared to AMP). It also provided confirmation that the laboratory generated data on basicity and volatility was applicable to plant and hence also the accuracy of the figures for predicted amine usage. (orig.)

  13. Comment on : "A novel approach for solving the Fisher equation using Exp-function method" [Phys. Lett. A 372 3836

    NARCIS (Netherlands)

    Kudryashov, Nikolai A.

    2009-01-01

    Using Exp-function method Ozis and Koroglu [T. Ozis, C. Koroglu, Phys. Lett. A 372 (2008) 3836] have found exact "solutions" of the Fisher equation. In this comment we demonstrate that all these solutions do not satisfy the Fisher equation. The efficiency of application of Exp-function method to

  14. Desenvolvimento de uma rede de sensores sem fio aplicada no monitoramento da variabilidade térmica em casas de vegetação

    OpenAIRE

    Barbosa, Rogério Zanarde [UNESP

    2015-01-01

    Este é um trabalho de tecnologia computacional aplicada na área agrícola, cujo objetivo principal do trabalho é desenvolver uma rede de sensores sem fio, que envolve aspectos de software e hardware, para o monitoramento térmico no interior de uma casa de vegetação. Além da rede propriamente dita, o trabalho também inclui a sua aplicação no levantamento quantitativo da variabilidade térmica na casa de vegetação o que pode ser aplicado em diversas atividades agrícolas a serem desenvolvidas no i...

  15. La colonisation de l’expérience politique

    Directory of Open Access Journals (Sweden)

    Marin Ledun

    2005-10-01

    Full Text Available En prenant pour objet les projets expérimentaux publics ou industriels en matière de TIC, dans ou à la marge de la sphère politique française, dès la fin des années soixante, cette recherche analyse, du point de vue des Sciences de l’Information et de la Communication, les enjeux liés à l’extension du dispositif des TIC dans les activités politiques et à la redéfinition de la place du sujet politique dans les procédures démocratiques.

  16. Cleanup Verification Package for the 118-F-5 PNL Sawdust Pit

    International Nuclear Information System (INIS)

    Habel, L.D.

    2008-01-01

    This cleanup verification package documents completion of remedial action, sampling activities, and compliance with cleanup criteria for the 118-F-5 Burial Ground, the PNL (Pacific Northwest Laboratory) Sawdust Pit. The 118-F-5 Burial Ground was an unlined trench that received radioactive sawdust from the floors of animal pens in the 100-F Experimental Animal Farm

  17. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S.

    Directory of Open Access Journals (Sweden)

    Lu Huang

    Full Text Available In many different human cancers, one of the HRAS, NRAS, or KRAS genes in the RAS family of small GTPases acquires an oncogenic mutation that renders the encoded protein constitutively GTP-bound and thereby active, which is well established to promote tumorigenesis. In addition to oncogenic mutations, accumulating evidence suggests that the wild-type isoforms may also be activated and contribute to oncogenic RAS-driven tumorigenesis. In this regard, redox-dependent reactions with cysteine 118 (C118 have been found to promote activation of wild-type HRAS and NRAS. We sought to determine if this residue is also important for the activation of wild-type KRAS and promotion of tumorigenesis. Thus, we mutated C118 to serine (C118S in wild-type KRAS to block redox-dependent reactions at this site. We now report that this mutation reduced the level of GTP-bound KRAS and impaired RAS signaling stimulated by the growth factor EGF. With regards to tumorigenesis, we also report that oncogenic HRAS-transformed human cells in which endogenous KRAS was knocked down and replaced with KRASC118S exhibited reduced xenograft tumor growth, as did oncogenic HRAS-transformed KrasC118S/C118S murine cells in which the C118S mutation was knocked into the endogenous Kras gene. Taken together, these data suggest a role for redox-dependent activation of wild-type KRAS through C118 in oncogenic HRAS-driven tumorigenesis.

  18. Multicentre survey of radiologically inserted gastrostomy feeding tube (RIG) in the UK

    International Nuclear Information System (INIS)

    Lowe, A.S.; Laasch, H.U.; Stephenson, S.; Butterfield, C.; Goodwin, M.; Kay, C.L.; Glancy, S.; Jackson, S.; Brown, D.; McLean, P.; Keanie, J.; Thrower, A.; Briggs, R.; Punekar, S.; Krishnan, S.; Thomas, B.; Yap, K.; Mullan, D.; Maskell, G.; Hancock, J.

    2012-01-01

    Aims: To evaluate the variance in current UK clinical practice and clinical outcomes for direct percutaneous radiologically inserted gastrostomy (RIG). Materials and methods: A prospective UK multicentre survey of RIG performed between October 2008 and August 2010 was performed through the British Society of Gastrointestinal and Abdominal Radiology (BSGAR). Results: Data from 684 patients were provided by 45 radiologists working at 17 UK centres. Two hundred and sixty-three cases (40%) were performed with loop-retained catheters, and 346 (53%) with balloon-retained devices. Sixty percent of all patients experienced pain in the first 24 h, but settled in the majority thereafter. Early complications, defined as occurring in the first 24 h, included minor bleeding (1%), wound infection (3%), peritonism (2%), and tube misplacement (1%). Late complications, defined as occurring between day 2 and day 30 post-procedure, included mild pain (30%), persisting peritonism (2%), and 30 day mortality of 1% (5/665). Pre-procedural antibiotics or anti-methicillin-resistant Staphylococcus aureus (MRSA) prophylaxis did not affect the rate of wound infection, peritonitis, post-procedural pain, or mortality. Ninety-three percent of cases were performed using gastropexy. Gastropexy decreased post-procedural pain (p < 0.001), but gastropexy-related complications occurred in 5% of patients. However, post-procedure pain increased with the number of gastropexy sutures used (p < 0.001). The use of gastropexy did not affect the overall complication rate or mortality. Post-procedure pain increased significantly as tube size increased (p < 0.001). The use of balloon-retention feeding tubes was associated with more pain than the deployment of loop-retention devices (p < 0.001). Conclusion: RIG is a relatively safe procedure with a mortality of 1%, with or without gastropexy. Pain is the commonest complication. The use of gastropexy, fixation dressing or skin sutures, smaller tube sizes, and

  19. Yield of 117Sb, 118mSb, 120mSb, 122Sb, 124Sb in reactions Sn (p, xn)

    International Nuclear Information System (INIS)

    Dmitriev, P.P.; Konstantinov, I.O.

    1993-01-01

    Yield of 117 Sb, 118m Sb, 120m Sb, 122 Sb, 124 Sb from thick target depending on proton energy is measured. The maximum proton energy is 21.7±0.2 MeV. Antimony isotopes yield in separate reactions when irradiating of tin isotopes with 100% enrichment is determined using the method published earlier. The methods for production of 117 Sb, 118m Sb, 120m Sb, 122 Sb, 124 Sb with high radioisotope purity are shown. 13 refs., 1 fig., 3 tabs

  20. Experimental rig to estimate the coefficient of friction between tire and surface in airplane touchdown simulations.

    Science.gov (United States)

    Li, Chengwei; Zhan, Liwei

    2015-08-01

    To estimate the coefficient of friction between tire and runway surface during airplane touchdowns, we designed an experimental rig to simulate such events and to record the impact and friction forces being executed. Because of noise in the measured signals, we developed a filtering method that is based on the ensemble empirical mode decomposition and the bandwidth of probability density function of each intrinsic mode function to extract friction and impact force signals. We can quantify the coefficient of friction by calculating the maximum values of the filtered force signals. Signal measurements are recorded for different drop heights and tire rotational speeds, and the corresponding coefficient of friction is calculated. The result shows that the values of the coefficient of friction change only slightly. The random noise and experimental artifact are the major reason of the change.

  1. DESENVOLVIMENTO E AVALIAÇÃO DE UM ANEMÔMETRO DE FIO QUENTE OPERANDO À TEMPERATURA CONSTANTE

    Directory of Open Access Journals (Sweden)

    Carlos Augusto de P. Sampaio

    1998-08-01

    Full Text Available RESUMO Esta pesquisa teve como objetivo desenvolver um anemômetro de fio quente para operar à temperatura constante usando-se, como elemento sensível, filamento de tungstênio de lâmpada incandescente, como braço da ponte de Wheatstone. Um circuito eletrônico foi construído e testado, permitindo controlar a tensão no sensor e restaurar o equilíbrio da ponte de Wheatstone em processos de troca de calor pelo sensor. Os resultados mostraram que a corrente elétrica e a temperatura de operação do sensor, mediante compromisso entre vida útil e sensibilidade, foram de 160mA e 140°C, respectivamente; a calibração com o sensor no circuito ponte de Wheatstone mostrou sensibilidade para medir a velocidade do ar no intervalo de 0,00 e 5,00m.s-1 e que o circuito eletrônico apresentou saturação para velocidades do ar inferiores a 0,50m.s-1.

  2. Advanced Subsonic Technology (AST) 22-Inch Low Noise Research Fan Rig Preliminary Design of ADP-Type Fan 3

    Science.gov (United States)

    Jeracki, Robert J. (Technical Monitor); Topol, David A.; Ingram, Clint L.; Larkin, Michael J.; Roche, Charles H.; Thulin, Robert D.

    2004-01-01

    This report presents results of the work completed on the preliminary design of Fan 3 of NASA s 22-inch Fan Low Noise Research project. Fan 3 was intended to build on the experience gained from Fans 1 and 2 by demonstrating noise reduction technology that surpasses 1992 levels by 6 dB. The work was performed as part of NASA s Advanced Subsonic Technology (AST) program. Work on this task was conducted in the areas of CFD code validation, acoustic prediction and validation, rotor parametric studies, and fan exit guide vane (FEGV) studies up to the time when a NASA decision was made to cancel the design, fabrication and testing phases of the work. The scope of the program changed accordingly to concentrate on two subtasks: (1) Rig data analysis and CFD code validation and (2) Fan and FEGV optimization studies. The results of the CFD code validation work showed that this tool predicts 3D flowfield features well from the blade trailing edge to about a chord downstream. The CFD tool loses accuracy as the distance from the trailing edge increases beyond a blade chord. The comparisons of noise predictions to rig test data showed that both the tone noise tool and the broadband noise tool demonstrated reasonable agreement with the data to the degree that these tools can reliably be used for design work. The section on rig airflow and inlet separation analysis describes the method used to determine total fan airflow, shows the good agreement of predicted boundary layer profiles to measured profiles, and shows separation angles of attack ranging from 29.5 to 27deg for the range of airflows tested. The results of the rotor parametric studies were significant in leading to the decision not to pursue a new rotor design for Fan 3 and resulted in recommendations to concentrate efforts on FEGV stator designs. The ensuing parametric study on FEGV designs showed the potential for 8 to 10 EPNdB noise reduction relative to the baseline.

  3. [Effect of physical properties of respiratory gas on pneumotachographic measurement of ventilation in newborn infants].

    Science.gov (United States)

    Foitzik, B; Schmalisch, G; Wauer, R R

    1994-04-01

    The measurement of ventilation in neonates has a number of specific characteristics; in contrast to lung function testing in adults, the inspiratory gas for neonates is often conditioned. In pneumotachographs (PNT) based on Hagen-Poiseuille's law, changes in physical characteristics of respiratory gas (temperature, humidity, pressure and oxygen fraction [FiO2]) produce a volume change as calculated with the ideal gas equation p*V/T = const; in addition, the viscosity of the gas is also changed, thus leading to measuring errors. In clinical practice, the effect of viscosity on volume measurement is often ignored. The accuracy of these empirical laws was investigated in a size 0 Fleisch-PNT using a flow-through technique and variously processed respiratory gas. Spontaneous breathing was simulated with the aid of a calibration syringe (20 ml) and a rate of 30 min-1. The largest change in viscosity (11.6% at 22 degrees C and dry gas) is found with an increase in FiO2 (21...100%). A rise in temperature from 24 to 35 degrees C (dry air) produced an increase in viscosity of 5.2%. An increase of humidity (0...90%, 35 degrees C) decreased the viscosity by 3%. A partial compensation of these viscosity errors is thus possible. Pressure change (0...50 mbar, under ambient conditions) caused no measurable viscosity error. With the exception of temperature, the measurements have shown good agreement between the measured volume measuring errors and those calculated from viscosity changes. If the respiratory gas differs from ambient air (e.g. elevated FiO2) or if the PNT is calibrated under BTPS conditions, changes in viscosity must not be neglected when performing accurate ventilation measurements. On the basis of the well-known physical laws of Dalton, Thiesen and Sutherland, a numerical correction of adequate accuracy is possible.

  4. Westinghouse says cartel rigged U.S. uranium market

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    On Oct. 15, 1976, Westinghouse filed a complaint in Federal court in Chicago charging that 29 U.S. and foreign uranium producers damaged Westinghouse by illegally rigging the uranium market; they also link the Atomic Industrial Forum to the U.S. activities of this cartel. Background information is presented for the charge, which has become the focal point of Westinghouse's defense against the uranium supply breach of contract suits filed against the firm by 27 electric utilities (3 filed in county court in Pittsburgh, 24 jointly in Federal court in Virginia). Westinghouse attorneys say that most of the evidence they have shows the existence of a cartel in the past, but they hope to show it is still operating in the U.S

  5. Development and Initial Testing of the Tiltrotor Test Rig

    Science.gov (United States)

    Acree, C. W., Jr.; Sheikman, A. L.

    2018-01-01

    The NASA Tiltrotor Test Rig (TTR) is a new, large-scale proprotor test system, developed jointly with the U.S. Army and Air Force, to develop a new, large-scale proprotor test system for the National Full-Scale Aerodynamics Complex (NFAC). The TTR is designed to test advanced proprotors up to 26 feet in diameter at speeds up to 300 knots, and even larger rotors at lower airspeeds. This combination of size and speed is unprecedented and is necessary for research into 21st-century tiltrotors and other advanced rotorcraft concepts. The TTR will provide critical data for validation of state-of-the-art design and analysis tools.

  6. 40 CFR 92.118 - Analyzer checks and calibrations.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92.118... sampling system at the sample probe or valve V2 at atmospheric pressure. Simultaneously, start the time...

  7. A method for assemblying support columns for a floating drill rig

    Energy Technology Data Exchange (ETDEWEB)

    Sheremetyev, D N; Kutnyakov, M I; Lobayev, S F

    1984-01-01

    The patent covers a method for assembling support columns for a floating drill rig, in which the first section of the support column is fed into a lifting and lowering device of the floating drill rig from above, while the subsequent sections are fed by means of a ballasted pontoon and winches from the bottom side into a notch in the body of the platform. In order to simplify assembly by increasing the precision of orientation when feeding the sections of the support columns into the notch in the body of the platform, guide retainers are installed in the first section of the support column, rope links are passed through them, some ends of which are attached to the drums of the cited winches, while the others are attached to the section fed from the bottom. Then the pontoon with the section fed from the bottom of the platform is balanced on the rope links, taking up the slack by means of the referenced winches, after which the lifting and lowering devices is used to lower the first section of the support column until it interfaces with the section fed from the bottom. The rope links are locked in the guide retainers and the abutted sections are lifted to the assembly zone by means of the lift and lowering device.

  8. Reparação do ligamento cruzado cranial de cães por tendão homólogo conservado em glicerina e associado a fio de náilon

    Directory of Open Access Journals (Sweden)

    Oliveira Simone Tostes de

    2003-01-01

    Full Text Available A ruptura do ligamento cruzado cranial (LCC é uma das patologias de maior prevalência no joelho de cães e sua correção é um problema atual. Após a ruptura experimental do LCC, em cães, implantou-se o tendão do músculo extensor longo dos dedos, homólogo, conservado em glicerina a 98%, associado ao fio de mononáilon, utilizando-se técnica intra-articular. Foram utilizados 18 cães com peso médio de 16,5kg, adultos, separados em três grupos (A, B e C e avaliados por 45, 80 e 120 dias de pós-operatório, respectivamente. Foi realizada avaliação clínica, radiográfica, macroscópica e histológica. A técnica demonstrou-se eficiente para o retorno funcional do membro promovendo estabilidade articular, apesar de o implante biológico ter sido reabsorvido na maioria dos animais, e do fio de náilon ter perdido sua tensão inicial.

  9. Modelling the nonlinear behaviour of an underplatform damper test rig for turbine applications

    Science.gov (United States)

    Pesaresi, L.; Salles, L.; Jones, A.; Green, J. S.; Schwingshackl, C. W.

    2017-02-01

    Underplatform dampers (UPD) are commonly used in aircraft engines to mitigate the risk of high-cycle fatigue failure of turbine blades. The energy dissipated at the friction contact interface of the damper reduces the vibration amplitude significantly, and the couplings of the blades can also lead to significant shifts of the resonance frequencies of the bladed disk. The highly nonlinear behaviour of bladed discs constrained by UPDs requires an advanced modelling approach to ensure that the correct damper geometry is selected during the design of the turbine, and that no unexpected resonance frequencies and amplitudes will occur in operation. Approaches based on an explicit model of the damper in combination with multi-harmonic balance solvers have emerged as a promising way to predict the nonlinear behaviour of UPDs correctly, however rigorous experimental validations are required before approaches of this type can be used with confidence. In this study, a nonlinear analysis based on an updated explicit damper model having different levels of detail is performed, and the results are evaluated against a newly-developed UPD test rig. Detailed linear finite element models are used as input for the nonlinear analysis, allowing the inclusion of damper flexibility and inertia effects. The nonlinear friction interface between the blades and the damper is described with a dense grid of 3D friction contact elements which allow accurate capturing of the underlying nonlinear mechanism that drives the global nonlinear behaviour. The introduced explicit damper model showed a great dependence on the correct contact pressure distribution. The use of an accurate, measurement based, distribution, better matched the nonlinear dynamic behaviour of the test rig. Good agreement with the measured frequency response data could only be reached when the zero harmonic term (constant term) was included in the multi-harmonic expansion of the nonlinear problem, highlighting its importance

  10. 50 CFR 18.118 - What are the mitigation, monitoring, and reporting requirements?

    Science.gov (United States)

    2010-10-01

    ... reporting requirements? 18.118 Section 18.118 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... avoid significant additive and synergistic effects from multiple oil and gas exploration activities on... conducted i.e., a plan of operation; (B) A food and waste management plan; (C) Personnel training materials...

  11. A thermal-hydraulic test rig for advanced fast reactor fuel assemblies

    International Nuclear Information System (INIS)

    Rapier, A.C.

    1989-03-01

    A new design of fast reactor fuel assemblies has been proposed in which the pins are supported in grids attached to the wrapper by flexible skirts. Coolant mixing is enhanced by the skirts diverting flow into the cluster of pins at each grid. There are insufficient empirical data available for the detailed design of the skirt or for the input to computer calculations of flow and heat transfer. A test rig to provide these data has been designed and built. (author)

  12. EXP-PAC: providing comparative analysis and storage of next generation gene expression data.

    Science.gov (United States)

    Church, Philip C; Goscinski, Andrzej; Lefèvre, Christophe

    2012-07-01

    Microarrays and more recently RNA sequencing has led to an increase in available gene expression data. How to manage and store this data is becoming a key issue. In response we have developed EXP-PAC, a web based software package for storage, management and analysis of gene expression and sequence data. Unique to this package is SQL based querying of gene expression data sets, distributed normalization of raw gene expression data and analysis of gene expression data across experiments and species. This package has been populated with lactation data in the international milk genomic consortium web portal (http://milkgenomics.org/). Source code is also available which can be hosted on a Windows, Linux or Mac APACHE server connected to a private or public network (http://mamsap.it.deakin.edu.au/~pcc/Release/EXP_PAC.html). Copyright © 2012 Elsevier Inc. All rights reserved.

  13. Optical fuel spray measurements

    Energy Technology Data Exchange (ETDEWEB)

    Hillamo, H.

    2011-07-01

    Diesel fuel sprays, including fuel/air mixing and the physics of two-phase jet formation, are discussed in the thesis. The fuel/air mixing strongly affects emissions formation in spray combustion processes where the local combustion conditions dictate the emission formation. This study comprises optical measurements both in pressurized spray test rigs and in a running engine.The studied fuel injection was arranged with a common rail injection system and the injectors were operated with a solenoid-based injection valve. Both marine and heavy-duty diesel engine injectors were used in the study. Optical fuel spray measurements were carried out with a laser-based double-framing camera system. This kind of equipments is usually used for flow field measurements with Particle Image Velocimetry technique (PIV) as well as for backlight imaging. Fundamental fuel spray properties and spray formation were studied in spray test rigs. These measurements involved studies of mixing, atomization, and the flow field. Test rig measurements were used to study the effect of individual injection parameters and component designs. Measurements of the fuel spray flow field, spray penetration, spray tip velocity, spray angle, spray structure, droplet accumulation, and droplet size estimates are shown. Measurement campaign in a running optically accessible large-bore medium-speed engine was also carried out. The results from engine tests were compared with equivalent test rig measurements, as well as computational results, to evaluate the level of understanding of sprays. It was shown that transient spray has an acceleration and a deceleration phase. Successive flow field measurements (PIV) in optically dense diesel spray resulted in local and average velocity data of diesel sprays. Processing fuel spray generates a flow field to surrounding gas and entrainment of surrounding gas into fuel jet was also seen at the sides of the spray. Laser sheet imaging revealed the inner structure of diesel

  14. 29 CFR 570.118 - Sixteen-year minimum.

    Science.gov (United States)

    2010-07-01

    ... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS, ORDERS AND STATEMENTS OF INTERPRETATION General Statements of Interpretation of the Child Labor Provisions of the Fair Labor Standards Act of 1938, as Amended Oppressive Child Labor § 570.118 Sixteen-year...

  15. Tank 241-TX-118 tank characterization plan

    International Nuclear Information System (INIS)

    Carpenter, B.C.

    1994-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-118

  16. Exact solitary wave solutions for some nonlinear evolution equations via Exp-function method

    International Nuclear Information System (INIS)

    Ebaid, A.

    2007-01-01

    Based on the Exp-function method, exact solutions for some nonlinear evolution equations are obtained. The KdV equation, Burgers' equation and the combined KdV-mKdV equation are chosen to illustrate the effectiveness of the method

  17. Characterization of alpha low level waste in 118 litre drums by passive and active neutron measurements in the promethee assay system

    International Nuclear Information System (INIS)

    Jallu, F.; Passard, C.; Mariani, A.; Ma, J.L.; Baudry, G.; Romeyer-Dherbey, J.; Recroix, H.; Rodriguez, M.; Loridon, J.; Denis, C.; Toubon, H.

    2003-01-01

    This paper deals with the PROMETHEE (PROMpt, epithermal and THErmal interrogation experiment) waste assay system for alpha low level waste (LLW) characterization. This device, including both passive and active neutron measurement methods, is developed at the French Atomic Energy Commission (C.E.A.), Cadarache Centre, in cooperation with COGEMA. Its purpose is to reach the requirements for incinerating alpha waste (less than 50 Bq[α], i.e. about 50 μg of Pu per gram of raw waste) in 118 litre- > drums. The PROMETHEE development and progress are performed with the help of simulation based on the Monte Carlo code MCNP4 [1]. These calculations are coupled with specific experiments in order to confirm calculated results and to obtain characteristics that can not be approached by the simulation (background for example). This paper presents the PROMETHEE measurement cell, its current performances, and studies performed at the laboratory about the most limiting parameters such as the matrix of the drum - its composition (H, Cl..), its density and its heterogeneity degree -the localization and the self-shielding properties of the contaminant. (orig.)

  18. Characterization of alpha low level waste in 118 litre drums by passive and active neutron measurements in the promethee assay system

    Energy Technology Data Exchange (ETDEWEB)

    Jallu, F.; Passard, C.; Mariani, A.; Ma, J.L.; Baudry, G.; Romeyer-Dherbey, J.; Recroix, H.; Rodriguez, M.; Loridon, J.; Denis, C. [French Atomic Energy Commission (C.E.A./Cadarache), DED/SCCD/LDMN, Durance (France); Toubon, H. [COGEMA, VELIZY-VILLACOUBLAY (France)

    2003-07-01

    This paper deals with the PROMETHEE (PROMpt, epithermal and THErmal interrogation experiment) waste assay system for alpha low level waste (LLW) characterization. This device, including both passive and active neutron measurement methods, is developed at the French Atomic Energy Commission (C.E.A.), Cadarache Centre, in cooperation with COGEMA. Its purpose is to reach the requirements for incinerating alpha waste (less than 50 Bq[{alpha}], i.e. about 50 {mu}g of Pu per gram of raw waste) in 118 litre-<> drums. The PROMETHEE development and progress are performed with the help of simulation based on the Monte Carlo code MCNP4 [1]. These calculations are coupled with specific experiments in order to confirm calculated results and to obtain characteristics that can not be approached by the simulation (background for example). This paper presents the PROMETHEE measurement cell, its current performances, and studies performed at the laboratory about the most limiting parameters such as the matrix of the drum - its composition (H, Cl..), its density and its heterogeneity degree -the localization and the self-shielding properties of the contaminant. (orig.)

  19. Focus : Le bassin versant expérimental du Moulin à Draix

    Directory of Open Access Journals (Sweden)

    LIÉBAULT, Frédéric

    2010-09-01

    Full Text Available Les petits bassins versants de montagne connaissent des crues soudaines et dévastatrices. Une des caractéristiques essentielles y est l’importance du transport de sédiments. Focus sur le bassin versant expérimental du Moulin à Draix dédié à l'étude de l'érosion et des crues rapides en montagne.

  20. 23 CFR 635.118 - Payroll and weekly statements.

    Science.gov (United States)

    2010-04-01

    ... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.118 Payroll and weekly statements. For all projects... contract provisions for the project, are to be retained by the STD for the time period pursuant to 49 CFR...

  1. Rare cancers in children - The EXPeRT Initiative: a report from the European Cooperative Study Group on Pediatric Rare Tumors.

    Science.gov (United States)

    Bisogno, G; Ferrari, A; Bien, E; Brecht, I B; Brennan, B; Cecchetto, G; Godzinski, J; Orbach, D; Reguerre, Y; Stachowicz-Stencel, T; Schneider, D T

    2012-10-01

    The low incidence and the heterogeneity of very rare tumors (VRTs) demand for international cooperation. In 2008, EXPeRT (European Cooperative Study Group for Pediatric Rare Tumors) was founded by national groups from Italy, France, United Kingdom, Poland and Germany. The first aims of EXPeRT were to agree on a uniform definition of VRTs and to develop the currently most relevant scientific questions. Current initiatives include international data exchange, retrospective and prospective studies of specific entities, and the development of harmonized and internationally recognized guidelines. Moreover, EXPeRT established a network for expert consultation to assist in clinical decision in VRTs. © Georg Thieme Verlag KG Stuttgart · New York.

  2. Investigation of intracochlear dual actuator stimulation in a scaled test rig

    Directory of Open Access Journals (Sweden)

    van Drunen Wouter J.

    2017-09-01

    Full Text Available For patients suffering from profound hearing loss or deafness still having respectable residual hearing in the low frequency range, the combination of a hearing aid with a cochlear implant results in the best quality of hearing perception (EAS – electric acoustic stimulation. In order to optimize EAS, ongoing research focusses on the integration of these stimuli in a single implant device. Within this study, the performance of piezoelectric actuators, particularly the dual actuator stimulation, in a scaled uncoiled test rig was investigated.

  3. STS-118 Astronaut Tracy Caldwell During Training

    Science.gov (United States)

    2006-01-01

    Tracy E. Caldwell, STS-118 astronaut and mission specialist, participates in a training session on the usage of a special device, used to lower oneself from a troubled shuttle, in the Space Vehicle Mockup Facility at the Johnson Space Center. Caldwell is wearing a training version of her shuttle launch and entry suit.

  4. Experimental Analysis of Mast Lifting and Bending Forces on Vibration Patterns Before and After Pinion Reinstallation in an OH-58 Transmission Test Rig

    Science.gov (United States)

    Huff, Edward M.; Lewicki, David G.; Tumer, Irem Y.; Decker, Harry; Barszez, Eric; Zakrajsek, James J.; Norvig, Peter (Technical Monitor)

    2000-01-01

    As part of a collaborative research program between NASA Ames Research Center (ARC), NASA Glenn Research Center (GRC), and the US Army Laboratory, a series of experiments is being performed in GRC's 500 HP OH-58 Transmission Test Rig facility and ARC's AH-I Cobra and OH-58c helicopters. The findings reported in this paper were drawn from Phase-I of a two-phase test-rig experiment, and are focused on the vibration response of an undamaged pinion gear operating in the transmission test rig. To simulate actual flight conditions, the transmission system was run at three torque levels, as well as two mast lifting and two mast bending levels. The test rig was also subjected to disassembly and reassembly of the main pinion housing to simulate the effect of maintenance operations. An analysis of variance based on the total power of the spectral distribution indicates the relative effect of each experimental factor, including Wong interactions with torque. Reinstallation of the main pinion assembly is shown to introduce changes in the vibration signature, suggesting the possibility of a strong effect of maintenance on HUMS design and use. Based on these results, further research will be conducted to compare these vibration responses with actual OH58c helicopter transmission vibration patterns.

  5. Chemical Passivation of Li(exp +)-Conducting Solid Electrolytes

    Science.gov (United States)

    West, William; Whitacre, Jay; Lim, James

    2008-01-01

    Plates of a solid electrolyte that exhibits high conductivity for positive lithium ions can now be passivated to prevent them from reacting with metallic lithium. Such passivation could enable the construction and operation of high-performance, long-life lithium-based rechargeable electrochemical cells containing metallic lithium anodes. The advantage of this approach, in comparison with a possible alternative approach utilizing lithium-ion graphitic anodes, is that metallic lithium anodes could afford significantly greater energy-storage densities. A major impediment to the development of such cells has been the fact that the available solid electrolytes having the requisite high Li(exp +)-ion conductivity are too highly chemically reactive with metallic lithium to be useful, while those solid electrolytes that do not react excessively with metallic lithium have conductivities too low to be useful. The present passivation method exploits the best features of both extremes of the solid-electrolyte spectrum. The basic idea is to coat a higher-conductivity, higher-reactivity solid electrolyte with a lower-conductivity, lower-reactivity solid electrolyte. One can then safely deposit metallic lithium in contact with the lower-reactivity solid electrolyte without incurring the undesired chemical reactions. The thickness of the lower-reactivity electrolyte must be great enough to afford the desired passivation but not so great as to contribute excessively to the electrical resistance of the cell. The feasibility of this method was demonstrated in experiments on plates of a commercial high-performance solid Li(exp +)- conducting electrolyte. Lithium phosphorous oxynitride (LiPON) was the solid electrolyte used for passivation. LiPON-coated solid-electrolyte plates were found to support electrochemical plating and stripping of Li metal. The electrical resistance contributed by the LiPON layers were found to be small relative to overall cell impedances.

  6. "Fan-Tip-Drive" High-Power-Density, Permanent Magnet Electric Motor and Test Rig Designed for a Nonpolluting Aircraft Propulsion Program

    Science.gov (United States)

    Brown, Gerald V.; Kascak, Albert F.

    2004-01-01

    A scaled blade-tip-drive test rig was designed at the NASA Glenn Research Center. The rig is a scaled version of a direct-current brushless motor that would be located in the shroud of a thrust fan. This geometry is very attractive since the allowable speed of the armature is approximately the speed of the blade tips (Mach 1 or 1100 ft/s). The magnetic pressure generated in the motor acts over a large area and, thus, produces a large force or torque. This large force multiplied by the large velocity results in a high-power-density motor.

  7. Réacteurs nucléaires expérimentaux

    OpenAIRE

    CHABRE , André; BONIN , Bernard

    2012-01-01

    International audience; Les réacteurs expérimentaux constituent une base nécessaire au développement et à l'évolution de l'énergie nucléaire. Ce sont eux qui ont ouvert la voie à l'utilisation du nucléaire avec la divergence de la première pile atomique CP1, en 1942, à Chicago, puis, dès la libération, celle de la pile atomique française ZOE, en 1948, au fort de Châtillon, démontrant ainsi l'aptitude à produire et à contrôler l'innovation technique majeure que constituait alors la réaction de...

  8. The application of He's exp-function method to a nonlinear differential-difference equation

    International Nuclear Information System (INIS)

    Dai Chaoqing; Cen Xu; Wu Shengsheng

    2009-01-01

    This paper applies He's exp-function method, which was originally proposed to find new exact travelling wave solutions of nonlinear partial differential equations (NPDEs) or coupled nonlinear partial differential equations (CNPDEs), to a nonlinear differential-difference equation, and some new travelling wave solutions are obtained.

  9. 41 CFR 102-118.65 - Can my agency receive electronic billing for payment of transportation services?

    Science.gov (United States)

    2010-07-01

    ... electronic billing for payment of transportation services? 102-118.65 Section 102-118.65 Public Contracts and... Transportation Services § 102-118.65 Can my agency receive electronic billing for payment of transportation... to use electronic billing for the procurement and billing of transportation services. ...

  10. Construction of rigged Hilbert spaces to describe resonances and virtual states

    International Nuclear Information System (INIS)

    Gadella, M.

    1983-01-01

    In the present communication we present a mathematical formalism for the description of resonances and virtual states. We start by constructing rigged Hilbert spaces of Hardy class functions restricted to the positive half of the real line. Then resonances and virtual states can be written as generalized eigenvectors of the total Hamiltonian. We also define time evolution on functionals. We see that the time evolution group U(t) splits into two semigroups, one for t > 0 and the other for t < 0, hence showing the irreversibility of the decaying process

  11. Construction of rigged Hilbert spaces to describe resonances and virtual states

    International Nuclear Information System (INIS)

    Gadella, M.

    1984-01-01

    In the present communication we present a mathematical formalism for the description of resonances and virtual states. We start by constructing rigged Hilbert spaces of Hardy class functions restricted to the positive half of the real line. Then resonances and virtual states can be written as generalized eigenvectors of the total Hamiltonian. We also define time evolution on functionals. We see that the time evolution group U(t) splits into two semigroups, one for t>0 and the other for t<0, hence showing the irreversibility of the decaying process. (orig.)

  12. TRAILER Project Overview. Tagging, Recognition and Acknowledgment of Informal Learning ExpeRiences

    NARCIS (Netherlands)

    García-Peñalvo, Francisco J.; Zangrando, Valentina; García Holgado, Alicia; Conde González, Miguel Ángel; Seoane Pardo, Antonio; Alier Forment, Marc; Janssen, José; Griffiths, Dai; Mykowska, Aleksandra; Ribeiro Alves, Gustavo; Minovic, Miroslav

    2012-01-01

    García-Peñalvo, F. J., Zangrando, V., García Holgado, A., Conde González, M. Á., Seoane Pardo, A. M., Alier Forment, M., Janssen, J., et al. (2012). TRAILER Project Overview. Tagging, Recognition and Acknowledgment of Informal Learning ExpeRiences. In F. J. García, L. Vicent, M. Ribó, A. Climent, J.

  13. Détermination expérimentale des paramètres de Wilson Experimental Dertermination of Wilson Parameters

    Directory of Open Access Journals (Sweden)

    Monfort J.-P.

    2006-11-01

    Full Text Available La volabilité relative ait; =(yilxil(Y;lxi des constituants d'un mélange binaire a été mesurée à partir d'un nouveau dispositif expérimental, on reporte les données d'équilibre liquide-vapeur obtenues à 45'C de plusieurs binaires : toluène-acétoni-trile, benzène-acétonitrile et benzène-n-heptane. En ajustant à l'équation de Wilson les données expérimentales de «i/; de ces constituants ainsi que des volatilités relatives des constituants des mélanges d'hydrocarbures-alcools, obtenues dans un précédent travail, on calcule les paramètres énergétiques. La prédiction des points de bulle de mélanges binaires et ternaires obtenue à partir de ces paramètres est satisfaisante. La méthode expérimentale ainsi proposée convient particulièrement pour la sélection des solvant extractifs utilisés dans la distillation extractive. From a new expérimental method, relative volatilities aiti = (yilxil(yilxi for a binary mixture are obtained; vapor-liquid equilibrium data are presented for several systems, i.e. toluene-acétonitrile, benzene-acétonitrile and benzene-n-heptane at 45°C. The two adjustable energyparameters of thé Wilson équation, are obtained by adopting thé «,/j data for these binary mixtures and for alcohol-hydrocarbon mixtures previously studied. Theresults obtained in predicting bubble-pressure data for binary and ternary mixtures are consistent with experimental data.

  14. Life as a sober citizen: Aldo Leopold's Wildlife Ecology 118

    Science.gov (United States)

    Theiss, Nancy Stearns

    This historic case study addressed the issue of the lack of citizen action toward environmentally responsible behavior. Although there have been studies regarding components of environmental responsible behavior [ERB], there has been little focus on historic models of exemplary figures of ERB. This study examined one of the first conservation courses in the United States, Wildlife Ecology 118, taught by Aldo Leopold (1887--1948) for 13 years at the University of Wisconsin. Today, Aldo Leopold is recognized as an exemplary conservationist whose land ethic is cited as providing the ecological approach needed for understanding the complex issues of modern society. The researcher conjectured that examination of one of the first environmental education courses could support and strengthen environmental education practices by providing a heuristic perspective. The researcher used two different strategies for analysis of the case. For Research Question One---"What were Leopold's teaching strategies in Wildlife Ecology 118?"---the researcher used methods of comparative historical analysis. The researcher examined the learning outcomes that Leopold used in Wildlife Ecology 118 and compared them against a rubric of the Four Strands for Environmental Education (North American Association for Environmental Education [NAAEE], 1999). The Four Strands for Environmental Education are the current teaching strategies used by educators. The results indicated that Wildlife Ecology 118 scored high in Knowledge of Processes and Systems and Environmental Problem Solving strands. Leopold relied on historic case examples and animal biographies to build stories that engaged students. Field trips gave students practical experience for environmental knowledge with special emphasis on phenology. For Research Question Two---"What was the context of the lessons in Wildlife Ecology 118?"---the researcher used environmental history methods for analysis. Context provided the knowledge and

  15. The response regulator expM is essential for the virulence of Erwinia carotovora subsp. carotovora and acts negatively on the sigma factor RpoS (sigma s).

    Science.gov (United States)

    Andersson, R A; Palva, E T; Pirhonen, M

    1999-07-01

    The main virulence factors of Erwinia carotovora subsp. carotovora, the secreted, extracellular cell-wall-degrading enzymes, are controlled by several regulatory mechanisms. We have isolated transposon mutants with reduced virulence on tobacco. One of these mutants, with a mutation in a gene designated expM, was characterized in this study. This mutant produces slightly reduced amounts of extracellular enzymes in vitro and the secretion of the enzymes is also affected. The expM wild-type allele was cloned together with an upstream gene, designated expL, that has an unknown function. The expM gene was sequenced and found to encode a protein with similarity to the RssB/SprE protein of Escherichia coli and the MviA protein of Salmonella typhimurium. These proteins belong to a new type of two-component response regulators that negatively regulate the stability of the Sigma factor RpoS (sigma s) at the protein level. The results of this study suggest that ExpM has a similar function in E. carotovora subsp. carotovora. We also provide evidence that the overproduction of RpoS in the expM mutant is an important factor for the reduced virulence phenotype and that it partly causes the observed phenotype seen in vitro. However, an expM/rpoS double mutant is still affected in secretion of extracellular enzymes, suggesting that ExpM in addition to RpoS also acts on other targets.

  16. Tank 241-TX-118 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-TX-118 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-TX-118 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  17. BabelFish-Tools for IEEE C37.118.2-compliant real-time synchrophasor data mediation

    Science.gov (United States)

    Almas, M. S.; Vanfretti, L.; Baudette, M.

    BabelFish (BF) is a real-time data mediator for development and fast prototyping of synchrophasor applications. BF is compliant with the synchrophasor data transmission IEEE Std C37.118.2-2011. BF establishes a TCP/IP connection with any Phasor Measurement Unit (PMU) or Phasor Data Concentrator (PDC) stream and parses the IEEE Std C37.118.2-2011 frames in real-time to provide access to raw numerical data in the LabVIEW environment. Furthermore, BF allows the user to select "data-of-interest" and transmit it to either a local or remote application using the User Datagram Protocol (UDP) in order to support both unicast and multicast communication. In the power systems Wide Area Monitoring Protection and Control (WAMPAC) domain, BF provides the first Free/Libre and Open Source Software (FLOSS) for the purpose of giving the users tools for fast prototyping of new applications processing PMU measurements in their chosen environment, thus liberating them of time consuming synchrophasor data handling and allowing them to develop applications in a modular fashion, without a need of a large and monolithic synchrophasor software environment.

  18. An Experimental Study on Dynamics of a Novel Dual-Belt Continuous Variable Transmission Based on a Newly Developed Test Rig

    Directory of Open Access Journals (Sweden)

    Pak Kin Wong

    2015-01-01

    Full Text Available A novel dual-belt Van Doorne’s continuous variable transmission (DBVCVT system, which is applicable to heavy-duty vehicles, has been previously proposed by the authors in order to improve the low torque capacity of traditional single-belt CVT. This DBVCVT is a novel design among continuously variable transmissions and is necessary to be prototyped for experimental study, and the analytical dynamic model for this DBVCVT also needs to be experimentally validated. So, this work originally fabricated a prototype of DBVCVT and integrates this prototype to a light-load hardware-in-the-loop test rig by replacing the engine and load equipment with the AC motor and magnetic powder dynamometer. Moreover, with the use of this newly developed test rig, this work implements the experimental study of this DBVCVT for the first time. The comparison of experimental and simulation results validates the previously proposed analytical model for DBVCVT, and some basic characteristics of the DBVCVT in terms of the reliability, speed ratio, and transmission efficiency are also experimentally studied. In all, this developed test rig with the analytical model lays the foundation for further study on this novel DBVCVT.

  19. Analogies et contrastes entre l'expédition d'Egypte et le voyage d'Humboldt et Bonpland

    Directory of Open Access Journals (Sweden)

    Drouin Jean-Marc

    2001-01-01

    Full Text Available Alexandre de Humbodlt et Aimé Bonpland avaient prévu de se joindre aux savants de l'expédition française en Egypte. Ayant dû renoncer à ce projet et ayant obtenu l'autorisation du gouvernement espagnol, il réalisèrent leur voyage en Amérique Latine. La quasi-simultanéité des deux expéditions invite à une comparaison. Les points communs ne manquent pas: la production éditoriale au retour, le souci de rendre la science visible, l'importance du repérage spatial et de la collecte naturalistes. Cependant, malgré ces ressemblances, le rapport aux pays étudiés est assez contrasté dans ces deux voyages: non seulement à cause du cadre politique mais aussi parce que la conception du travail scientifique est différente. Tandis que l'expédition d'Egypte réduit seulement la distance du terrain au cabinet sans changer fondamentalement la nature de leur rapport, Humboldt transforme le terrain en laboratoire.

  20. RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

    Directory of Open Access Journals (Sweden)

    Michael Gale Jr.

    2011-06-01

    Full Text Available The RNA helicase family of RIG-I-like receptors (RLRs is a key component of host defense mechanisms responsible for detecting viruses and triggering innate immune signaling cascades to control viral replication and dissemination. As cytoplasm-based sensors, RLRs recognize foreign RNA in the cell and activate a cascade of antiviral responses including the induction of type I interferons, inflammasome activation, and expression of proinflammatory cytokines and chemokines. This review provides a brief overview of RLR function, ligand interactions, and downstream signaling events with an expanded discussion on the therapeutic potential of targeting RLRs for immune stimulation and treatment of virus infection.

  1. Global regulators ExpA (GacA) and KdgR modulate extracellular enzyme gene expression through the RsmA-rsmB system in Erwinia carotovora subsp. carotovora.

    Science.gov (United States)

    Hyytiäinen, H; Montesano, M; Palva, E T

    2001-08-01

    The production of the main virulence determinants, the extracellular plant cell wall-degrading enzymes, and hence virulence of Erwinia carotovora subsp. carotovora is controlled by a complex regulatory network. One of the global regulators, the response regulator ExpA, a GacA homolog, is required for transcriptional activation of the extracellular enzyme genes of this soft-rot pathogen. To elucidate the mechanism of ExpA control as well as interactions with other regulatory systems, we isolated second-site transposon mutants that would suppress the enzyme-negative phenotype of an expA (gacA) mutant. Inactivation of kdgR resulted in partial restoration of extracellular enzyme production and virulence to the expA mutant, suggesting an interaction between the two regulatory pathways. This interaction was mediated by the RsmA-rsmB system. Northern analysis was used to show that the regulatory rsmB RNA was under positive control of ExpA. Conversely, the expression of rsmA encoding a global repressor was under negative control of ExpA and positive control of KdgR. This study indicates a central role for the RsmA-rsmB regulatory system during pathogenesis, integrating signals from the ExpA (GacA) and KdgR global regulators of extracellular enzyme production in E. carotovora subsp. carotovora.

  2. Technical specification for IR rig manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Han Hyon Soo; Cho, W. K.; Kim, S. D.; Park, U. J.; Hong, S. B.; Yoo, K. M

    2000-10-01

    IR Rig is one of the equipments are required in HANARO core for a radioisotope target. The various conditions like high radiation, high heat, rapid flow and vibration may cause swelling, Brittleness and acceleration of corrosion in HANARO core. These specific problems can be prevented and the safety of such equipment are prerequisite as well as durableness and surveillance. Therefore, the selection of material has to be made on the basis of small cross-section area, low energy emission by the gamma ray due to the absorption of neutron and short half life. The body is consist of aluminum and Inconel-750 was used for the internal spring(coil) which is known to be durable. The whole production process including the purchase of accessory, mechanical processing, welding and assembly was carried out according to the standard procedure to meet the requirement. A design, manufacture, utilization of reactor core and the other relevant uses were fit to class ''T'' to certify the whole process as general. And design, fabrication, analytical test, materials and accessory were carried out based on the ASME, ASTM, ANSI, AWS, JIS and KS standard.

  3. TRAC-PF1/MOD3 calculations of Savannah River Laboratory Rig FA single-annulus heated experiments

    International Nuclear Information System (INIS)

    Fischer, S.R.; McDaniel, C.K.

    1992-01-01

    This paper presents the results of TRAC-PF1/MOD3 benchmarks of the Rig FA experiments performed at the Savannah River Laboratory to simulate prototypic reactor fuel assembly behavior over a range of fluid conditions typical of the emergency cooling system (ECS) phase of a loss-of-coolant accident (LOCA). The primary purpose of this work was to use the SRL Rig FA tests to qualify the TRAC-PF1/MOD3 computer code and models for computing Mark-22 fuel assembly LOCA/ECS power limits. This qualification effort was part of a larger effort undertaken by the Los Alamos National Laboratory for the US Department of Energy to independently confirm power limits for the Savannah River Site K Reactor. The results of this benchmark effort as discussed in this paper demonstrate that TRAC/PF1/MOD3 coupled with proper modeling is capable of simulating thermal-hydraulic phenomena typical of that encountered in Mark-22 fuel assembly during LOCA/ECS conditions

  4. 41 CFR 102-118.80 - Who is responsible for keeping my agency's electronic commerce transportation billing records?

    Science.gov (United States)

    2010-07-01

    ... keeping my agency's electronic commerce transportation billing records? 102-118.80 Section 102-118.80... Transportation and Transportation Services § 102-118.80 Who is responsible for keeping my agency's electronic commerce transportation billing records? Your agency's internal financial regulations will identify...

  5. Microtubules Nonlinear Models Dynamics Investigations through the exp(−Φ(ξ-Expansion Method Implementation

    Directory of Open Access Journals (Sweden)

    Nur Alam

    2016-02-01

    Full Text Available In this research article, we present exact solutions with parameters for two nonlinear model partial differential equations(PDEs describing microtubules, by implementing the exp(−Φ(ξ-Expansion Method. The considered models, describing highly nonlinear dynamics of microtubules, can be reduced to nonlinear ordinary differential equations. While the first PDE describes the longitudinal model of nonlinear dynamics of microtubules, the second one describes the nonlinear model of dynamics of radial dislocations in microtubules. The acquired solutions are then graphically presented, and their distinct properties are enumerated in respect to the corresponding dynamic behavior of the microtubules they model. Various patterns, including but not limited to regular, singular kink-like, as well as periodicity exhibiting ones, are detected. Being the method of choice herein, the exp(−Φ(ξ-Expansion Method not disappointing in the least, is found and declared highly efficient.

  6. Analisis Keandalan Struktur Padeye Berdasarkan Konfigurasi Rigging pada Lifting Upper Deck Modul Modec dengan Pendekatan Dinamik

    Directory of Open Access Journals (Sweden)

    Iqbal Gayuh Raharjaning Mukti Sumarsono

    2017-01-01

    Full Text Available Di dalam perusahaan yang bergerak dalam bidang fabrikasi, lifting merupakan salah satu tahapan terpenting dalam membangun bangunan lepas pantai sehingga diperlukan perhitungan dan analisis tambahan untuk memperhatikan apakah struktur tersebut aman ataupun tidak. Sekenario lifting berdasarkan konfigurasi rigging dapat dibuat untuk menentukan rigging equipment yang tepat. Pada kasus ini, struktur yang di-lifting adalah struktur upper deck dari modul MODEC yang dikerjakan oleh PT. GPS Batam. Deck ini memiliki panjang sekitar 19,5 m dan lebar 9 m. Berat total struktur dengan equipment sebesar 55 ton. Konfigurasi rigging yang akan digunakan ada tiga, yaitu Model A (tanpa spreader bar, Model B (satu spreader bar, dan Model C (dua spreader bar. Dari ketiga konfigurasi tersebut akan diperoleh dimensi padeye yang berbeda- beda. Model A, Model B, dan Model C memiliki diameter hole padeye masing-masing sebesar 74 mm, 65 mm, dan 52 mm. Tegangan dan UC tertinggi sama- sama terjadi pada Model A sebesar 17625,99 psi dan untuk UC sebesar 0,52. Tetapi hal ini berbanding terbalik apabila ditinjau dari daerah lubang. Tegangan ataupun UC yang lebih tinggi jatuh pada Model C yang menggunakan dua spreader bar sebesar 13936,58 psi dan nilai UC sebesar 0,45. Tegangan yang terjadi di attachments maupun sekitar hole dijadikan variabel dalam mencari keandalan yang terjadi pada tiap padeye dengan metode Mean value first order second moment (MVFOSM. Sehingga didapatkan Probality of Failure (PoF pada attachments padeye pada Model A, B, dan C masing- masing sebesar 0,126%, 0,064 %, dan 0,0001 %. Sedangkan PoF pada hole padeye sebesar 0,062% untuk Model A, 0,10 % untuk Model B, dan 0,23% untuk Model C.

  7. Comparação entre dois fios de sutura não absorvíveis na anastomose traqueal término-terminal em cães Comparison of two nonabsorbable suture materials in the end-to-end tracheal anastomosis in dogs

    Directory of Open Access Journals (Sweden)

    Sheila Canevese Rahal

    1995-01-01

    Full Text Available Doze cães sem raça definida, com idade variando entre 1 e 6 anos e peso de 6 a 20kg, foram submetidos a ressecção traqueal e anastomose término-terminal, na qual foram testados os fios poliéster trançado não capilar e náilon monofilamento. Seis animais, cada três com um mesmo tipo de fio de sutura, sofreram a excisão equivalente a três anéis traqueais. Com 15 dias foi executada uma nova intervenção onde se ressecou o equivalente a mais seis anéis, perfazendo um total de nove. Ao final de outros 15 dias foram sacrificados. Os outros seis animais, cada três com um mesmo tipo de fio, foram submetidos à excisão equivalente a três anéis traqueais e mantidos por 43 dias. As traquéias foram avaliadas por exames clínicos, radiográficos, macroscópicos e histopatológicos. O fio de náilon monofilamento apresentou menos reação tecidual do que o poliéster trançado não capilar, promoveu uma anastomose segura e com menor chance de formação de granuloma.Twelve mongrel dogs, with age between 1 and 6 years old and weight between 12 and 40 pounds, were submitted to tracheal resection and end-to-end anastomosis in which were tested braided polyester no capillary and monofilament nylon materiais. Six animais, every threeones with a same type of suture material, suffered the excision equivalent to three tracheal rings. A new intervention was performed with fifteen days, in which the equivalent of more six tracheal rings were removed, completing the total of nine. At the end of more fifteen days they were sacrificed. The other six animals, every three with a same type of suture material, were submitted to the excision equivalent to three tracheal rings and maintained for 43 days. The tracheal anastomosis were evaluated to clinic, radiographic, macroscopic and histopathologic studies. The monofilament nylon material exhibited less reaction than polyester and promoted a secure anastomosis with less risk of granuloma formation.

  8. Foreign awakenings: rig work in war-torn Sudan convinces Canadians their civilized version of industry is needed

    International Nuclear Information System (INIS)

    Lorenz, A.

    2000-01-01

    Experiences of some Canadian geologists working in Sudan are described. Glad to be back in Canada after several years of exploration work for various international exploration companies, they have fond memories of the people, who for the most part live under very primitive conditions, and constant exposure to the ravages of tribal wars. They characterize the attitude of Canadians working in Sudan towards the native population as one that puts high values on human rights, safety, work ethics, and individual responsibility. They defend Canadian presence in these far-off regions as beneficial to the native population, by bringing Canadian standards and a civilized version of industry to an area that has seen very little of that in the past. In contrast to the situation on Canadian rigs, on Chinese oil rigs favoritism and racism are the rule; the Chinese do not see that humanitarian issues are any of their concerns

  9. Foreign awakenings: rig work in war-torn Sudan convinces Canadians their civilized version of industry is needed

    Energy Technology Data Exchange (ETDEWEB)

    Lorenz, A.

    2000-05-01

    Experiences of some Canadian geologists working in Sudan are described. Glad to be back in Canada after several years of exploration work for various international exploration companies, they have fond memories of the people, who for the most part live under very primitive conditions, and constant exposure to the ravages of tribal wars. They characterize the attitude of Canadians working in Sudan towards the native population as one that puts high values on human rights, safety, work ethics, and individual responsibility. They defend Canadian presence in these far-off regions as beneficial to the native population, by bringing Canadian standards and a civilized version of industry to an area that has seen very little of that in the past. In contrast to the situation on Canadian rigs, on Chinese oil rigs favoritism and racism are the rule; the Chinese do not see that humanitarian issues are any of their concerns.

  10. Functional effects of Toll-like receptor (TLR3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells.

    Directory of Open Access Journals (Sweden)

    Lotta Tengroth

    Full Text Available The human nasal epithelium is an important physical barrier, and a part of the innate immune defense that protect against pathogens. The epithelial cells recognize microbial components by pattern-recognition receptors (PRRs, and thereby trigger an immune response. Even though TLR3, TLR7, TLR9, RIG-I and MDA-5 are all known to respond to viral stimulation, their potential role in chronic airway inflammation triggered by local cytokine release remains to be established.mRNA and corresponding protein expression of TLR3, TLR7, TLR9, RIG-I and MDA-5 were analyzed in nasal biopsies and various upper airway epithelial cell lines using real-time reverse transcription PCR, immunohistochemistry and flow cytometry. Ligand induced, cytokine release, was evaluated with ELISA.Nasal biopsies were found to express TLR3, TLR7, TLR9, RIG-I and MDA-5, with the most abundant expression in the surface epithelium. These receptors were verified in primary human nasal epithelial cell (HNEC as well as in the airway epithelial cell lines Detroit-562 and FaDu. Poly(I:C (TLR3 and R-837 (TLR7 stimulation increased secretion of IL-6 and GM-CSF from the nasal mucosa and the epithelial cell lines. CpG (TLR9 stimulation caused release of IL-8 in the nasal mucosa and in FaDu. Poly(I:C/LyoVec (RIG-I/MDA-5 stimulation activated the secretion of IFN-β in the nasal mucosa. A corresponding release was also detected from HNEC and Detroit-562.The nasal epithelium has the ability to recognize viral intrusion through TLR and RLR receptors, and the subsequent response might have a role in exacerbation of inflammatory diseases like allergic rhinitis and chronic rhinosinusitis.

  11. Synthesis of the isotopes of elements 118 and 116 in the 249Cf and 245Cm+48Ca fusion reactions

    International Nuclear Information System (INIS)

    Oganessian, Y T; Utyonkov, V K; Lobanov, Y V; Abdullin, F S; Polyakov, A N; Sagaidak, R N; Shirokovsky, I V; Tsyganov, Y S; Voinov, A A; Gulbekian, G G; Bogomolov, S L; Gikal, B N; Mezentsev, A N; Iliev, S; Subbotin, V G; Sukhov, A M; Subotic, K; Zagrebaev, V I; Vostokin, G K; Itkis, M G; Moody, K J; . Patin, J B; Shaughnessy, D A; Stoyer, M A; Stoyer, N J; Wilk, P A; Kenneally, J M; Landrum, J H; Wild, J F; Lougheed, R W

    2006-01-01

    The decay properties of 290 116 and 291 116, and the dependence of their production cross sections on the excitation energies of the compound nucleus, 293 116, have been measured in the 245 Cm( 48 Ca,xn) 293-x 116 reaction. These isotopes of element 116 are the decay daughters of element 118 isotopes, which are produced via the 249 Cf+ 48 Ca reaction. They performed the element 118 experiment at two projectile energies, corresponding to 297 118 compound nucleus excitation energies of E* = 29.2 ± 2.5 and 34.4 ± 2.3 MeV. During an irradiation with a total beam dose of 4.1 x 10 19 48 Ca projectiles, three similar decay chains consisting of two or three consecutive α decays and terminated by a spontaneous fission (SF) with high total kinetic energy of about 230 MeV were observed. The three decay chains originated from the even-even isotope 294 118 (E α = 11.65 ± 0.06 MeV, T α = 0.89 -0.31 +1.07 ms) produced in the 3n-evaporation channel of the 249 Cf+ 48 Ca reaction with a maximum cross section of 0.5 -0.3 +1.6 pb

  12. Electromagnetic E2 Transition Probabilities in 120Xe And 118Te - N=66 Nuclei

    International Nuclear Information System (INIS)

    Pasternak, A.A.; Efimov, A.D.; Podsvirova, E.O.

    2001-01-01

    Lifetimes of the yrast states in 120 Xe and the ground state band below and above band crossing in 118 Te have been measured by DSAM in the 111 Cd( 12 C, 3n) reaction and by DSAM and RDM in the 109 Ag( 13 C, p3n) reaction, respectively. The experimental data are compared with calculation done in the framework of the IBM1 model in the 0(6) and SU(5) limits. (author)

  13. Deposition stress effects on thermal barrier coating burner rig life

    Science.gov (United States)

    Watson, J. W.; Levine, S. R.

    1984-01-01

    A study of the effect of plasma spray processing parameters on the life of a two layer thermal barrier coating was conducted. The ceramic layer was plasma sprayed at plasma arc currents of 900 and 600 amps onto uncooled tubes, cooled tubes, and solid bars of Waspalloy in a lathe with 1 or 8 passes of the plasma gun. These processing changes affected the residual stress state of the coating. When the specimens were tested in a Mach 0.3 cyclic burner rig at 1130 deg C, a wide range of coating lives resulted. Processing factors which reduced the residual stress state in the coating, such as reduced plasma temperature and increased heat dissipation, significantly increased coating life.

  14. Burner rig alkali salt corrosion of several high temperature alloys

    Science.gov (United States)

    Deadmore, D. L.; Lowell, C. E.

    1977-01-01

    The hot corrosion of five alloys was studied in cyclic tests in a Mach 0.3 burner rig into whose combustion chamber various aqueous salt solutions were injected. Three nickel-based alloys, a cobalt-base alloy, and an iron-base alloy were studied at temperatures of 700, 800, 900, and 1000 C with various salt concentrations and compositions. The relative resistance of the alloys to hot corrosion attack was found to vary with temperature and both concentration and composition of the injected salt solution. Results indicate that the corrosion of these alloys is a function of both the presence of salt condensed as a liquid on the surface and of the composition of the gas phases present.

  15. Numerical simulation of the RF ion source RIG-10

    International Nuclear Information System (INIS)

    Arzt, T.

    1988-01-01

    A two-dimensional model for the numerical simulation of the inductively coupled radio-frequency (RF) ion source RIG-10 is presented. Due to the ambipolar characteristics of a discharge operating with hydrogen gas, the model consists of an equation for the space charge imbalance, Poisson's equation for the self-consistent presheath potential and the ion momentum transport equation. For a relatively broad range of operation and design parameters, the model allows the reproduction and prediction of the RF discharge behaviour in a systematic way and, hence, computes the 2D distribution of the ion current density within the source. By implementing relevant discharge physics, the model can provide an appropriate tool for ion source design with respect to an application in the field of neutral beam injection. (author)

  16. Intégration d'un système de Retour d'Expériences à un PLM

    OpenAIRE

    Bertin, Aurélie

    2012-01-01

    Les travaux présentés dans cette thèse s’inscrivent dans une problématique d’amélioration continue appliquée aux produits et aux processus industriels, par la mise en place d’un système de Retour d’Expérience (REx) couplé au système PLM (Product Lifecycle Management) de gestion du cycle de vie du produit. Les développements, menés dans le cadre d’un partenarial industriel, ciblent l’établissement d’une solution de valorisation du patrimoine immatériel de l’entreprise, constitué des expérience...

  17. 41 CFR 102-118.260 - Must my agency send all quotations, tenders, or contracts with a TSP to GSA?

    Science.gov (United States)

    2010-07-01

    ... quotations, tenders, or contracts with a TSP to GSA? 102-118.260 Section 102-118.260 Public Contracts and... REGULATION TRANSPORTATION 118-TRANSPORTATION PAYMENT AND AUDIT Use of Government Billing Documents Quotations, Tenders Or Contracts § 102-118.260 Must my agency send all quotations, tenders, or contracts with a TSP to...

  18. A decision support system to dynamic management of the scheduling workover rigs for onshore Potiguar Basin; Um sistema de apoio a decisao para o gerenciamento dinamico das sondas de producao terrestre da Bacia Potiguar

    Energy Technology Data Exchange (ETDEWEB)

    Maia, Rosiery S.; Bittencourt, Valnaide [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Dept. de Engenharia da Computacao e Automacao (DCA); Aloise, Daniel [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil). Dept. de Informatica; Aloise, Dario J. [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil); Moura, Luiz S.S. [PETROBRAS S.A., Natal, RN (Brazil)

    2004-07-01

    The onshore Potiguar basin has nowadays around 5.000 artificial lifting petroleum wells, distributed into 80 fields located on the states of Rio Grande do Norte and Ceara, representing approximately 8% of the national oil production. For that, well maintenance service, realized by Workover Rigs, is essential to preserve the oil productivity of the reservoirs on these fields. However, as the number of rigs is lower than to the number of wells needing maintenance, the task of administrating the management of such equipment according to the demand created by the wells, generates an optimization problem. The decision for a rig intervention on a well depends on parameters such as flow rate, depth, wasted time on intervention, distance from the rig to the next well, type of operation, rig capacity, environmental risks, etc. The objective of this paper is to present an interactive Computational System for Support Decision to the optimized management of the wells attended by the rig fleet. Generically, the software has the following components: dynamic heuristical algorithms, meta heuristical Variable Neighborhood Search, with local search mechanisms, interconnection algorithm, database and graphical user interface. This paper contains knowledge in operational search and optimization, software engineering, database and user interface. (author)

  19. Design and simulation of the rotating test rig in the INDUFLAP project

    DEFF Research Database (Denmark)

    Barlas, Thanasis K.; Aagaard Madsen, Helge; Løgstrup Andersen, Tom

    The general description and objectives of the rotating test rig at the Risø campus of DTU are presented, as used for the aeroelastic testing of a controllable rubber trailing edge flap (CRTEF) system in the INDUFLAP project. The design of all new components is presented, including the electrical...... drive, the pitch system, the boom, and the wing/flap section. The overall instrumentation of the components used for the aeroelastic testing is described. Moreover, the aeroelastic model simulating the setup is described, and predictions of steady and dynamic loading along with the aeroelastic analysis...

  20. Development and verification of a reciprocating test rig designed for investigation of piston ring tribology

    DEFF Research Database (Denmark)

    Pedersen, Michael Torben; Imran, Tajammal; Klit, Peder

    2009-01-01

    This paper describes the development and verification of a reciprocating test rig, which was designed to study the piston ring tribology. A crank mechanism is used to generate a reciprocating motion for a moving plate, which acts as the liner. A stationary block acting as the ring package is loaded......, which is suitable for the study of piston ring tribology....

  1. E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue.

    Science.gov (United States)

    Lim, Jung Hwa; Shin, Hee Won; Chung, Kyung-Sook; Kim, Nam-Soon; Kim, Ju Hee; Jung, Hong-Ryul; Im, Dong-Soo; Jung, Cho-Rok

    Here, we show that E2-EPF ubiquitin carrier protein (UCP) elongated E3-independent polyubiquitin chains on the lysine residues of von Hippel-Lindau protein (pVHL) and its own lysine residues both in vitro and in vivo. The initiation of the ubiquitin reaction depended on not only Lys11 linkage but also the Lys6, Lys48 and Lys63 residues of ubiquitin, which were involved in polyubiquitin chain formation on UCP itself. UCP self-association occurred through the UBC domain, which also contributed to the interaction with pVHL. The polyubiquitin chains appeared on the N-terminus of UCP in vivo, which indicated that the N-terminus of UCP contains target lysines for polyubiquitination. The Lys76 residue of UCP was the most critical site for auto-ubiquitination, whereas the polyubiquitin chain formation on pVHL occurred on all three of its lysines (Lys159, Lys171 and Lys196). A UCP mutant in which Cys118 was changed to alanine (UCPC118A) did not form a polyubiquitin chain but did strongly accumulate mono- and di-ubiquitin via auto-ubiquitination. Polyubiquitin chain formation required the coordination of Cys95 and Cys118 between two interacting molecules. The mechanism of the polyubiquitin chain reaction of UCP may involve the transfer of ubiquitin from Cys95 to Cys118 by trans-thiolation, with polyubiquitin chains forming at Cys118 by reversible thioester bonding. The polyubiquitin chains are then moved to the lysine residues of the substrate by irreversible isopeptide bonding. During the elongation of the ubiquitin chain, an active Cys118 residue is required in both parts of UCP, namely, the catalytic enzyme and the substrate. In conclusion, UCP possesses not only E2 ubiquitin conjugating enzyme activity but also E3 ubiquitin ligase activity, and Cys118 is critical for polyubiquitin chain formation.

  2. E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue.

    Directory of Open Access Journals (Sweden)

    Jung Hwa Lim

    Full Text Available Here, we show that E2-EPF ubiquitin carrier protein (UCP elongated E3-independent polyubiquitin chains on the lysine residues of von Hippel-Lindau protein (pVHL and its own lysine residues both in vitro and in vivo. The initiation of the ubiquitin reaction depended on not only Lys11 linkage but also the Lys6, Lys48 and Lys63 residues of ubiquitin, which were involved in polyubiquitin chain formation on UCP itself. UCP self-association occurred through the UBC domain, which also contributed to the interaction with pVHL. The polyubiquitin chains appeared on the N-terminus of UCP in vivo, which indicated that the N-terminus of UCP contains target lysines for polyubiquitination. The Lys76 residue of UCP was the most critical site for auto-ubiquitination, whereas the polyubiquitin chain formation on pVHL occurred on all three of its lysines (Lys159, Lys171 and Lys196. A UCP mutant in which Cys118 was changed to alanine (UCPC118A did not form a polyubiquitin chain but did strongly accumulate mono- and di-ubiquitin via auto-ubiquitination. Polyubiquitin chain formation required the coordination of Cys95 and Cys118 between two interacting molecules. The mechanism of the polyubiquitin chain reaction of UCP may involve the transfer of ubiquitin from Cys95 to Cys118 by trans-thiolation, with polyubiquitin chains forming at Cys118 by reversible thioester bonding. The polyubiquitin chains are then moved to the lysine residues of the substrate by irreversible isopeptide bonding. During the elongation of the ubiquitin chain, an active Cys118 residue is required in both parts of UCP, namely, the catalytic enzyme and the substrate. In conclusion, UCP possesses not only E2 ubiquitin conjugating enzyme activity but also E3 ubiquitin ligase activity, and Cys118 is critical for polyubiquitin chain formation.

  3. [Predictive factors for failure of non-invasive positive pressure ventilation in immunosuppressed patients with acute respiratory failure].

    Science.gov (United States)

    Jia, Xiangli; Yan, Ci; Xu, Sicheng; Gu, Xingli; Wan, Qiufeng; Hu, Xinying; Li, Jingwen; Liu, Guangming; Caikai, Shareli; Guo, Zhijin

    2018-02-01

    To evaluate the predictive factors for failure of non-invasive positive pressure ventilation (NIPPV) in immunosuppressed patients with acute respiratory failure (ARF). The clinical data of 118 immuno-deficient patients treated with NIPPV in the respiratory and intensive care unit (RICU) of the First Affiliated Hospital of Xinjiang Medical University from January 2012 to August 2017 were retrospectively analyzed. The patients were divided into a non-endotracheal intubation (ETI) group (n = 62) and ETI group (n = 56) according to whether ETI was performed during the hospitalization period or not. Each observed indicator was analyzed by univariate analysis, and factors leading to failure of NIPPV were further analyzed by Logistic regression. Receiver operating characteristic (ROC) curve was plotted to evaluate the predictive value of risk factors for failure of NIPPV in immunosuppressed patients with ARF. The non-intubation rate for NIPPV in immunosuppressed patients was 50.8% (60/118). Compared with the non-ETI group, the body temperature, pH value in the ETI group were significantly increased, the partial pressure of arterial carbon dioxide (PaCO 2 ) was significantly decreased, the ratio of oxygenation index (PaO 2 /FiO 2 ) failure of NIPPV. ROC curve analysis showed that the APACHE II score ≥ 20 and PaO 2 /FiO 2 failure of NIPPV, the area under ROC curve (AUC) of the APACHE II score ≥ 20 was 0.787, the sensitivity was 83.93%, the specificity was 69.35%, the positive predict value (PPV) was 71.21%, the negative predict value (NPV) was 82.69%, the positive likelihood ratio (PLR) was 2.74, the negative likelihood ratio (NLR) was 0.23, and Youden index was 0.53; the AUC of PaO 2 /FiO 2 failure of NIPPV in immunocompromised patients.

  4. Modeling, simulation and design optimization of a hoisting rig active heave compensation system

    OpenAIRE

    Gu, Peter; Walid, Ahmed Ahmed; Iskandarani, Yousef; Karimi, Hamid Reza

    2013-01-01

    Published version of an article in the journal: International Journal of Machine Learning and Cybernetics. Also available from the publisher at: http://dx.doi.org/10.1007/s13042-012-0076-x The objective of this paper is to present an approach in developing a virtual active heave compensation system for a draw-works on a hoisting rig. A virtual system enables quicker overall product development time of a physical system as well as flexibility in optimizing the design parameters. Development...

  5. Sodium test of the Super-Phenix full size primary pump shaft on the CPV-1 test rig at ENEA-Brasimone

    International Nuclear Information System (INIS)

    Contardi, T.; Rapezzi, L.; Partiti, C.; Zola, M.; Denimal, P.

    1984-01-01

    Tests on FBR Superphenix primary pump shaft were performed within the sodium-cooled FBR common research and development programs provided for by the cooperation agreement between ENEA and CEA. These tests were performed in CPV-1 plant ENEA - Brasimone Energy Research Center. The CPV-1 rig was built by FIAT-TTG and reproduces the reactor operating conditions (sodium-temperature and level, shaft inclination, etc..). Furthermore, CPV-1 rig's most interesting feature is its possibility to apply seismic stresses to test section by means of an oleodynamic actuator. Pivoterie-1 test section was made by JEUMONT-SCHNEIDER which built Superphenix pumps too; it was given to ENEA by FIAT-TTG. Seismic tests were performed with the cooperation of ISMES and FIAT-TTG. (author)

  6. Influence of twin and multi-rig trawl systems on CPUE in the Danish Norway lobster (Nephrops norvegicus) fishery

    DEFF Research Database (Denmark)

    Feekings, Jordan P.; Berg, Casper Willestofte; Krag, Ludvig Ahm

    2016-01-01

    analyse catchrates of four target species, Norway lobster (Nephrops norvegicus), cod (Gadus morhua), plaice (Pleuronectesplatessa) and haddock (Melanogrammus aeglefinus), to try and understand how the use of multi-rig trawlshave altered catch rates within the Danish demersal trawl fishery over the last 16...

  7. How Useful is Extravascular Lung Water Measurement in Managing Lung Injury in Intensive Care Unit?

    Science.gov (United States)

    Bhattacharjee, Anirban; Pradhan, Debasis; Bhattacharyya, Prithwis; Dey, Samarjit; Chhunthang, Daniala; Handique, Akash; Barman, Angkita; Yunus, Mohd

    2017-08-01

    The primary goal of septic shock management is optimization of organ perfusion, often at the risk of overloading the interstitium and causing pulmonary edema. The conventionally used end points of resuscitation do not generally include volumetric parameters such as extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI). This study aimed to assess the prognostic value of EVLWI and PVPI by calculating their correlation with the severity of lung injury. This prospective observational study included twenty mechanically ventilated critically ill patients with Acute Physiology and Chronic Health Evaluation score (APACHE II) >20. EVLWI and PVPI were measured using transpulmonary thermodilution, and simultaneously, PaO 2 :FiO 2 ratio, alveolar-arterial gradient of oxygen (AaDO 2 ), and chest radiograph scores from two radiologists were obtained. The correlation of EVLWI and PVPI with chest radiograph scores, PaO 2 :FiO 2 ratio, and AaDO 2 were calculated. The inter-observer agreement between the two radiologists was tested using kappa test. EVLWI and PVPI correlated modestly with PaO 2 :FiO 2 ( r = -0.32, P = 0.0004; r = -0.39, P = 0.0001). There was a better correlation of EVLWI and PVPI with PaO 2 :FiO 2 ratio ( r = -0.71, P < 0.0001; r = -0.58, P = 0.0001) in the acute respiratory distress syndrome (ARDS) subgroup. The EVLWI values correlated significantly with corresponding chest radiograph scores ( r = 0.71, P < 0.0001 for observer 1 and r = 0.68, P < 0.0001 for observer 2). EVLWI and PVPI may have a prognostic significance in the assessment of lung injury in septic shock patients with ARDS. Further research is required to reveal the usefulness of EVLWI as an end point of fluid resuscitation in the management of septic shock with ARDS.

  8. Exergetic analysis of autonomous power complex for drilling rig

    Science.gov (United States)

    Lebedev, V. A.; Karabuta, V. S.

    2017-10-01

    The article considers the issue of increasing the energy efficiency of power equipment of the drilling rig. At present diverse types of power plants are used in power supply systems. When designing and choosing a power plant, one of the main criteria is its energy efficiency. The main indicator in this case is the effective efficiency factor calculated by the method of thermal balances. In the article, it is suggested to use the exergy method to determine energy efficiency, which allows to perform estimations of the thermodynamic perfection degree of the system by the example of a gas turbine plant: relative estimation (exergetic efficiency factor) and an absolute estimation. An exergetic analysis of the gas turbine plant operating in a simple scheme was carried out using the program WaterSteamPro. Exergy losses in equipment elements are calculated.

  9. Field Engineers' Scheduling at Oil Rigs: a Case Study

    Directory of Open Access Journals (Sweden)

    Y. S. Usmani

    2012-02-01

    Full Text Available Oil exploration and production operations face a number of challenges. Professional planners have to design solutions for various practical problems or issues. However, the time consumed is often very extensive because of the large number of possible solutions. Further, the matter of choosing the best solution remains. The present paper investigates a problem related to leading companies in the energy and chemical manufacturing sector of the oil and gas industry. Each company’s field engineers are expensive and valuable assets. Therefore, an optimized roster is rather important. In the present paper, the objective is to design a field engineers’ schedule which would be both feasible and satisfying towards the various demands of rigs, with minimum operational cost to the company. An efficient and quick optimization technique is presented to schedule the shifts of field engineers.

  10. 47 CFR 15.118 - Cable ready consumer electronics equipment.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Cable ready consumer electronics equipment. 15... Unintentional Radiators § 15.118 Cable ready consumer electronics equipment. (a) All consumer electronics TV... provisions of this section. Consumer electronics TV receiving equipment that includes features intended for...

  11. Exact traveling wave solutions of fractional order Boussinesq-like equations by applying Exp-function method

    Directory of Open Access Journals (Sweden)

    Rahmatullah

    2018-03-01

    Full Text Available We have computed new exact traveling wave solutions, including complex solutions of fractional order Boussinesq-Like equations, occurring in physical sciences and engineering, by applying Exp-function method. The method is blended with fractional complex transformation and modified Riemann-Liouville fractional order operator. Our obtained solutions are verified by substituting back into their corresponding equations. To the best of our knowledge, no other technique has been reported to cope with the said fractional order nonlinear problems combined with variety of exact solutions. Graphically, fractional order solution curves are shown to be strongly related to each other and most importantly, tend to fixate on their integer order solution curve. Our solutions comprise high frequencies and very small amplitude of the wave responses. Keywords: Exp-function method, New exact traveling wave solutions, Modified Riemann-Liouville derivative, Fractional complex transformation, Fractional order Boussinesq-like equations, Symbolic computation

  12. 41 CFR 102-118.130 - Must my agency use a GBL for express, courier, or small package shipments?

    Science.gov (United States)

    2010-07-01

    ... package express delivery, the terms and conditions of that contract are binding. ... for express, courier, or small package shipments? 102-118.130 Section 102-118.130 Public Contracts and... Transportation Services § 102-118.130 Must my agency use a GBL for express, courier, or small package shipments...

  13. Numerical study of the static and pitching RISØ-B1-18 airfoil

    DEFF Research Database (Denmark)

    Bertagnolio, Franck

    2004-01-01

    The objective of this report is the better understanding of the physics of the aeroelastic motion of wind turbine blades in order to improve the numerical models used for their design. In this study, the case of the RISØ-B1-18 airfoil which was equippedand measured in an open jet wind tunnel...... that are available both for the static airfoil and in the case of pitching motions. It is shown that the Navier-Stokes simulations can reproduced the maincharacteristic features of the flow. The DES model seems also to be able to reproduce some details of the unsteady aerodynamics. The Navier-Stokes computations can...

  14. Hydrolysis and photolysis of diacylhydrazines-type insect growth regulator JS-118 in aqueous solutions under abiotic conditions.

    Science.gov (United States)

    Hu, J-Y; Liu, C; Zhang, Y-C; Zheng, Z-X

    2009-05-01

    JS-118 is a diacylhydrazines-type insect growth regulator which is now used extensively in China. The hydrolysis and photolysis of the pesticide JS-118 in aqueous solutions have been assessed under natural and controlled conditions in this project. Hydrolysis experimental results show that JS-118 is quite stable in aqueous solutions in dark, with no significant variations be observed in degradation under various conditions. Abiotic hydrolysis is relatively unimportant compared to photolysis. The rate of photodecomposition of JS-118 in aqueous solutions follows first-order kinetics both in UV radiation and natural sunlight. The degradation rates are faster under UV light than sunlight, with the half-lives (t (1/2) = ln2/k) of 6.00-10.85 min and 6.63-10.16 day, respectively. Under UV light, two major photoproducts are detected, and tentatively identified according to HPLC-MS spectral information as N-t-butyl-N-(3,5-dimethylbenzoyl) and 3,7-dimethyl-benzoatedihydrofuran. The corresponding photolysis pathways of JS-118 are also proposed. The results obtained indicate that direct photoreaction is an important dissipation pathway of JS-118 in natural water systems.

  15. Improvement of Measurement Accuracy of Coolant Flow in a Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jintae; Kim, Jong-Bum; Joung, Chang-Young; Ahn, Sung-Ho; Heo, Sung-Ho; Jang, Seoyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this study, to improve the measurement accuracy of coolant flow in a coolant flow simulator, elimination of external noise are enhanced by adding ground pattern in the control panel and earth around signal cables. In addition, a heating unit is added to strengthen the fluctuation signal by heating the coolant because the source of signals are heat energy. Experimental results using the improved system shows good agreement with the reference flow rate. The measurement error is reduced dramatically compared with the previous measurement accuracy and it will help to analyze the performance of nuclear fuels. For further works, out of pile test will be carried out by fabricating a test rig mockup and inspect the feasibility of the developed system. To verify the performance of a newly developed nuclear fuel, irradiation test needs to be carried out in the research reactor and measure the irradiation behavior such as fuel temperature, fission gas release, neutron dose, coolant temperature, and coolant flow rate. In particular, the heat generation rate of nuclear fuels can be measured indirectly by measuring temperature variation of coolant which passes by the fuel rod and its flow rate. However, it is very difficult to measure the flow rate of coolant at the fuel rod owing to the narrow gap between components of the test rig. In nuclear fields, noise analysis using thermocouples in the test rig has been applied to measure the flow velocity of coolant which circulates through the test loop.

  16. Valor predictor del cociente saturación hemoglobina/fio2 en pacientes pediátricos con insuficiencia respiratoria aguda debida a neumonía tratados con ventilación no invasiva. Predictive value of the pulse oximetric saturation/fraction of inspired oxygen ratio in pediatric patients with acute respiratory failure due to pneumonia treated with non-invasive ventilation

    OpenAIRE

    Palanca Arias, Daniel

    2014-01-01

    RESUMEN: El uso de la ventilación no invasiva (VNI) en pacientes con fracaso respiratorio hipoxémico debido a neumonía es controvertido, alcanzando elevadas tasas de fracaso en el Síndrome de Distrés Respiratorio Agudo (SDRA). Recientemente, el cociente SpO2/FiO2 (SF) se ha equiparado al cociente paO2/FiO2 (PF) para la valoración del SDRA. Determinamos en una cohorte de pacientes, diagnosticados de neumonía y tratados con VNI, si el cociente SF es una variable con valor predictor de fraca...

  17. Hot Wire Measurements in a Axisymmetric Shear Layer with Swirl

    Science.gov (United States)

    Ewing, D.; Pollard, A.

    1996-11-01

    It is well known that the introduction of swirl in an axisymmetric jet can influence the development of and mixing in the near field of the jet. Recent efforts to compute this flow have demonstrated that the development of the near field is dependent on parameters at the jet outlet other than distribution of the swirl component, such as the distribution the mean radial velocity (Xai, J.L., Smith, B.L., Benim, A. C., Schmidli, J., and Yadigaroglu, G. (1996) Influence of Boundary Conditions on Swirling Flow in Combustors, Proc. ASME Fluid. Eng. Div. Summer Meeting), San Diego, Ca., July 7-11.. An experimental rig has been designed to produce co-axial round and annular swirling jets with uniform outlet conditions in each flow. The flow rate and swirl component from each of these jets can be controlled independently and the rig can be configured to produce both co- and counter-swirling flows. Thus, the rig can be used to carry out an extensive investigation of the effect of swirl on the development of axisymmetric flows. The key design features of the rig and the first sets of hot-wire measurements in the shear layer will be reported here.

  18. Comportamento termomecânico de compósitos ativos preparados com nanocompósitos epóxi/argila organofílica e fios de liga Ni-Ti com memória de forma Thermomechanical behavior of active composites prepared with epoxy/organoclay nanocomposites and Ni-Ti shape memory alloy wires

    Directory of Open Access Journals (Sweden)

    Artur S. C. Leal

    2012-01-01

    Full Text Available Neste trabalho, nanocompósitos epóxi/argila organofílica foram selecionados como matriz por apresentarem valores de temperatura de transição vítrea (Tg e estabilidade térmica suficientemente alta para que fios de uma liga com memória de forma (LMF possam ser incorporados. Para tanto, quatro frações volumétricas de fios LMF de Ni-Ti (1,55, 2,56, 3,57 e 4,54% foram embebidas na matriz epoxídica diglicidil éter do bisfenol-A (DGEBA, reticulada com a amina aromática 4,4’-diamino difenil sulfona (DDS contendo 1 pcr da argila bentonita purificada organofiliada (APOC. A formação do nanocompósito foi confirmada por análise de difração de raio X, enquanto a transformação de fase dos fios de Ni-Ti foi determinada por análise dinâmico-mecânica (DMA. As amostras dos compósitos ativos preparados a partir da matriz de nanocompósito e fios de Ni-Ti foram caracterizadas principalmente por DMA. De acordo com os resultados obtidos foi constatada uma recuperação do módulo de armazenamento do compósito ativo durante o aquecimento na faixa de transformação de fase dos fios de Ni-Ti quando a fração volumétrica foi mantida em torno de 3,5%.In this work, epoxy/organoclay nanocomposites were selected as matrix for presenting high enough glass transition temperature (Tg and thermal stability values in order to be incorporated in shape memory alloys (SMA. Four volume fractions of SMA wires containing Ni-Ti (1.55, 2.56, 3.57 and 4.54% were embedded in diglycidyl ether of bisphenol A (DGEBA, cured with the aromatic amine 4,4’-diamino diphenyl sulfone (DDS and containing 1 phr of purified organobentonite (APOC. The formation of nanocomposite was confirmed by X ray diffraction analysis, while the phase transformation of Ni-Ti wires was determined by dynamic mechanical analysis (DMA. Samples of the active composites prepared from nanocomposite matrix and Ni-Ti wires were mainly characterized by DMA. A recovery of the storage modulus of

  19. 25 CFR 900.118 - Do these “construction contract” regulations apply to construction management services?

    Science.gov (United States)

    2010-04-01

    ... construction management services? 900.118 Section 900.118 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE...” regulations apply to construction management services? No. Construction management services may be contracted separately under section 108 of the Act. Construction management services consultants and/or Indian tribe or...

  20. Partis islamistes et démocratisation : expérience du Parti de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Partis islamistes et démocratisation : expérience du Parti de la justice et du développement (Turquie). En Turquie, les élections de novembre 2002 ont été remportées par un nouveau parti politique d'orientation islamiste, l'AKP, qui détient environ les deux tiers des sièges au Parlement. La victoire de l'AKP traduit ...

  1. Closure Report for Corrective Action Unit 118: Area 27 Super Kukla Facility, Nevada Test Site, Nevada, Revision 0

    International Nuclear Information System (INIS)

    Mark Burmeister

    2007-01-01

    This CR provides documentation and justification for the closure of CAU 118 without further corrective action. This justification is based on process knowledge and the results of the investigative and closure activities conducted in accordance with the CAU 118 SAFER Plan: Streamlined Approach for Environmental Restoration (SAFER) Plan for CAU 118: Area 27 Super Kukla Facility, Nevada Test Site, Nevada (NNSA/NSO, 2006). The SAFER Plan provides information relating to site history as well as the scope and planning of the investigation. This CR also provides the analytical and radiological survey data to confirm that the remediation goals were met as specified in the CAU 118 SAFER Plan (NNSA/NSO, 2006). The Nevada Division of Environmental Protection (NDEP) approved the CAU 118 SAFER Plan (Murphy, 2006), which recommends closure in place with use restrictions (URs)

  2. Characterization of the lubricity of bio-oil/diesel fuel blends by high frequency reciprocating test rig

    International Nuclear Information System (INIS)

    Xu, Yufu; Wang, Qiongjie; Hu, Xianguo; Li, Chuan; Zhu, Xifeng

    2010-01-01

    The diesel fuel was mixed with the rice husk bio-oil using some emulsifiers based on the theory of Hydrophile-Lipophile Balance (HLB). The lubricity of the bio-oil/diesel fuel blend was studied on a High Frequency Reciprocating Test Rig (HFRR) according to ASTM D 6079-2004. The microscopic topography and chemical composition on the worn surface were analyzed respectively using scanning electron microscopy (SEM) and energy dispersive spectrometer (EDS). The profile and surface roughness of the rubbed trace were measured using a profilometer. The chemical group and composition were studied by a Fourier transform infrared spectrometry (FTIR). The results showed that the lubrication ability of the present fuel blend was better than that of the Chinese conventional diesel fuel (number zero). However, the anti-corrosion and anti-wear properties of the fuel blend were not satisfactory in comparison with those of conventional diesel fuel.

  3. A method for measuring the inertia properties of rigid bodies

    Science.gov (United States)

    Gobbi, M.; Mastinu, G.; Previati, G.

    2011-01-01

    A method for the measurement of the inertia properties of rigid bodies is presented. Given a rigid body and its mass, the method allows to measure (identify) the centre of gravity location and the inertia tensor during a single test. The proposed technique is based on the analysis of the free motion of a multi-cable pendulum to which the body under consideration is connected. The motion of the pendulum and the forces acting on the system are recorded and the inertia properties are identified by means of a proper mathematical procedure based on a least square estimation. After the body is positioned on the test rig, the full identification procedure takes less than 10 min. The natural frequencies of the pendulum and the accelerations involved are quite low, making this method suitable for many practical applications. In this paper, the proposed method is described and two test rigs are presented: the first is developed for bodies up to 3500 kg and the second for bodies up to 400 kg. A validation of the measurement method is performed with satisfactory results. The test rig holds a third part quality certificate according to an ISO 9001 standard and could be scaled up to measure the inertia properties of huge bodies, such as trucks, airplanes or even ships.

  4. Seismic tests in sodium of the SPX-1 primary pump shaft carried out in the CPV-1 test rig at ENEA-Brasimone

    International Nuclear Information System (INIS)

    Contardi, T.; Rapezzi, L.; Le Coz, P.; Tigeot, Y.; Partiti, C.; Zola, M.; Denimal, P.

    1988-01-01

    Dynamic tests were carried out by ISMES, on behalf of ENEA and CEA and in co-operation with FIAT/TTG, on a SPX-1 primary pump shaft. These tests were conducted, mainly in sodium, in the CPV-1 test rig at the ENEA Brasimone Center. The excitation was applied to the flange supporting the hydrostatic bearing. After some preliminary analysis performed in absence of liquid sodium and at ambient temperature, the following tests were performed on the rig filled with sodium at operating temperature: (A) sine sweeps between 1 and 15 Hz, (B) ambient vibration investigation, and (C) seismic tests with a SSE acceleration time-history (20 s duration) calculated by CEA at hydrostatic bearing level. Two sets of seismic tests were carried out, each time increasing amplitudes up to 70% of SSE. This value was not exceeded for safety reasons and actuator power limit. The first set of tests began in nominal operating conditions; when 70% of SSE was reached, pressure feed to hydrostatic bearing was reduced lowering its effective support. This simulated a larger earthquake. The second set of tests was representative of SPX-1 pump actual operating conditions, because both hydrostatic bearing pressure and shaft rotating speed were simultaneously reduced following the primary pump characteristic curve. The tests allowed the SPX-1 pump rotating set to be widely qualified. Among the main results, it is worth noting that the stiffness of the hydrostatic bearing system was generally compatible with seismic requirements. Finally, it is worth pointing out that, in order to allow the above-mentioned tests to be carried out, a full seismic qualification of the CPV-1 test rig was necessary: thus, this rig might be used in the future for further seismic tests on LMFBR components and systems in sodium. (author). Figs and tabs

  5. Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss) ▿ †

    Science.gov (United States)

    Chang, Mingxian; Collet, Bertrand; Nie, Pin; Lester, Katherine; Campbell, Scott; Secombes, Christopher J.; Zou, Jun

    2011-01-01

    The retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) comprise three homologues: RIG-I, melanoma differentiation-associated gene 5 (MDA5), and laboratory of genetics and physiology 2 (LGP2). They activate the host interferon (IFN) system upon recognition of viral RNA pathogen-associated molecular patterns (PAMPs) in the cytoplasm. Bioinformatic analysis of the sequenced vertebrate genomes suggests that the cytosolic surveillance system is conserved in lower vertebrates, and recent functional studies have confirmed that RIG-I is important to fish antiviral immunity. In this study, we have identified MDA5 and LGP2 homologues from rainbow trout Oncorhynchus mykiss and an additional LGP2 variant with an incomplete C-terminal domain of RIG-I. Trout MDA5 and LGP2 were constitutively produced in fibroblast and macrophage cell lines and upregulated by poly(I:C), recombinant IFN, or infection by RNA viruses (viral hemorrhagic septicemia virus and salmon alphavirus) with a single-stranded positive or negative genome. Overexpression of MDA5 and LGP2 but not of the LGP2 variant resulted in significant accumulation of Mx transcripts in cultured cells, which correlated with a marked enhancement of protection against viral infection. These results demonstrate that both MDA5 and LGP2 are important RLRs in host surveillance against infection of both negative and positive viruses and that the LGP2 variant with a deletion of 54 amino acids at the C terminus acts as a negative regulator for LGP2-elicited antiviral signaling by competing for the viral RNA PAMPs. Interestingly, MDA5 expression was not affected by overexpressed LGP2 in transfected cells and vice versa, suggesting that they likely act in parallel as positive regulators for IFN production. PMID:21680521

  6. Numerical solution to generalized Burgers'-Fisher equation using Exp-function method hybridized with heuristic computation.

    Science.gov (United States)

    Malik, Suheel Abdullah; Qureshi, Ijaz Mansoor; Amir, Muhammad; Malik, Aqdas Naveed; Haq, Ihsanul

    2015-01-01

    In this paper, a new heuristic scheme for the approximate solution of the generalized Burgers'-Fisher equation is proposed. The scheme is based on the hybridization of Exp-function method with nature inspired algorithm. The given nonlinear partial differential equation (NPDE) through substitution is converted into a nonlinear ordinary differential equation (NODE). The travelling wave solution is approximated by the Exp-function method with unknown parameters. The unknown parameters are estimated by transforming the NODE into an equivalent global error minimization problem by using a fitness function. The popular genetic algorithm (GA) is used to solve the minimization problem, and to achieve the unknown parameters. The proposed scheme is successfully implemented to solve the generalized Burgers'-Fisher equation. The comparison of numerical results with the exact solutions, and the solutions obtained using some traditional methods, including adomian decomposition method (ADM), homotopy perturbation method (HPM), and optimal homotopy asymptotic method (OHAM), show that the suggested scheme is fairly accurate and viable for solving such problems.

  7. Numerical solution to generalized Burgers'-Fisher equation using Exp-function method hybridized with heuristic computation.

    Directory of Open Access Journals (Sweden)

    Suheel Abdullah Malik

    Full Text Available In this paper, a new heuristic scheme for the approximate solution of the generalized Burgers'-Fisher equation is proposed. The scheme is based on the hybridization of Exp-function method with nature inspired algorithm. The given nonlinear partial differential equation (NPDE through substitution is converted into a nonlinear ordinary differential equation (NODE. The travelling wave solution is approximated by the Exp-function method with unknown parameters. The unknown parameters are estimated by transforming the NODE into an equivalent global error minimization problem by using a fitness function. The popular genetic algorithm (GA is used to solve the minimization problem, and to achieve the unknown parameters. The proposed scheme is successfully implemented to solve the generalized Burgers'-Fisher equation. The comparison of numerical results with the exact solutions, and the solutions obtained using some traditional methods, including adomian decomposition method (ADM, homotopy perturbation method (HPM, and optimal homotopy asymptotic method (OHAM, show that the suggested scheme is fairly accurate and viable for solving such problems.

  8. Ballistic and Cyclic Rig Testing of Braided Composite Fan Case Structures

    Science.gov (United States)

    Watson, William R.; Roberts, Gary D.; Pereira, J. Michael; Braley, Michael S.

    2015-01-01

    FAA fan blade-out certification testing on turbofan engines occurs very late in an engine's development program and is very costly. It is of utmost importance to approach the FAA Certification engine test with a high degree of confidence that the containment structure will not only contain the high-energy debris, but that it will also withstand the cyclic loads that occur with engine spooldown and continued rotation as the non-running engine maintains a low rotor RPM due to forced airflow as the engine-out aircraft returns to an airport. Accurate rig testing is needed for predicting and understanding material behavior of the fan case structure during all phases of this fan blade-out event.

  9. Provendo resiliência em uma rede de sensores sem fio linear e esparsa através de veículo aéreo não tripulado

    OpenAIRE

    Heitor de Freitas Vieira

    2015-01-01

    A mitigação de desastres naturais exige respostas rápidas e confiáveis. No Brasil, a estação de chuvas provoca muitos alagamentos em regiões urbanas e, para monitorar esse fenômeno, foi instalada em São Carlos-SP uma rede de sensores sem fio para acompanhar o nível de água dos rios da cidade. Entretanto, essa rede de sensores está suscetível a falhas que podem comprometer o funcionamento do sistema, e a adoção de mecanismos redundantes e de redes móveis 3G podem acarretar em custos proibitivo...

  10. Subcritical Measurements Research Program for Fresh and Spent Materials Test Reactor Fuels

    International Nuclear Information System (INIS)

    Blanchard, A.

    1999-01-01

    'A series of subcritical noise measurements were performed on fresh and spent University of Missouri Research Reactor fuel assemblies. These experimental measurements were performed for the purposes of providing benchmark quality data for validating transport theory computer codes and nuclear cross-section data used to perform criticality safety analyses for highly enriched, uranium-aluminum Material Test Reactor fuel assemblies. A mechanical test rig was designed and built to hold up to four fuel assemblies and neutron detectors in a subcritical array. The rig provided researchers with the ability to evaluate the reactivity effects of variable fuel/detector spacing, fuel rotation, and insertion of metal reflector plates into the lattice.'

  11. 33 CFR 118.100 - Retroreflective panels on bridge piers.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Retroreflective panels on bridge... SECURITY BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.100 Retroreflective panels on bridge piers. The... 12 inches square. (c) To mark bridge piers or channel sides on bridges not required to have bridge...

  12. Re-rigging Othering: Subversive Infantilisation in Contemporary Bosnian-Herzegovinian Prose

    Directory of Open Access Journals (Sweden)

    Fedja Borčak

    2014-12-01

    Full Text Available In this article I put forward the concept of subversive infantilisation to designate a phenomenon in contemporary Bosnian literature, which by using a certain kind of childish outlook on the world undermines paternalistic and balkanist Western discourse on Bosnia and Herzegovina. By analysing primarily the portrayal of the role of mass media in a few literary texts, principally books by Nenad Veličkovié and Miljenko Jergovié, I highlight the way in which these texts 're-rig' and by means of irony and exaggeration illuminate the problematic logic inherent in the subject position from which one represents the other. Textual characteristics of subversive infantilisation are contextualised further and seen as a discursive continuation of experiences of the 1990s war in Bosnia and Herzegovina.

  13. Cleanup Verification Package for the 118-B-6, 108-B Solid Waste Burial Ground

    International Nuclear Information System (INIS)

    Proctor, M.L.

    2006-01-01

    This cleanup verification package documents completion of remedial action for the 118-B-6, 108-B Solid Waste Burial Ground. The 118-B-6 site consisted of 2 concrete pipes buried vertically in the ground and capped by a concrete pad with steel lids. The site was used for the disposal of wastes from the 'metal line' of the P-10 Tritium Separation Project.

  14. The Brimmond Reservoir extending the Forties Field into the millenium by maximizing profits without extensive rig upgrades

    Energy Technology Data Exchange (ETDEWEB)

    Smith, L.; Perras, L. [Noble Drilling (United Kingdom)

    1998-12-31

    Drilling a horizontal well with a minimum facilities workover rig in the Brimmond Field (North Sea) which overlies the Forties Reservoir, was described. Feasibility studies indicated that further development of the Brimmond Field would require extensive rig upgrade to be able to drill the horizontal well within recognized industry parameters. Since the upgrading of the drilling package would have delayed the project by several months, as well as making it uneconomical, a number of critical operations were identified and analyzed, which led to introducing `new technology` - premixed cement, leading edge LWD tools and hole cleanup techniques. The first horizontal sidetrack was successfully completed with the minimum facilities drilling package and production commenced at an initial rate of 2.4 mbd dry oil from a 13 ft cased hole gravel pack utilizing an existing Forties Field producing well. The original Paleocene interval was abandoned with cement plugs prior to milling a window on the 9-5/8 inch casing and installing a gravel pack. Steady production of this new well led to consideration of further development of the field. 4 figs.

  15. Violence and Votes in Nigeria: The Dominance of Incumbents in the Use of Violence to Rig Elections

    Directory of Open Access Journals (Sweden)

    Hakeem Onapajo

    2014-01-01

    Full Text Available Which party uses violence to influence election outcomes? There are two existing perspectives that have offered responses to this critical question. One is a more popular position indicating that the incumbent party, more than the opposition party, makes use of violence with the aim of rigging elections; the other is a more radical perspective that suggests that electoral violence is more associated with the weakest party than with the incumbent. This paper seeks to contribute to the ongoing debate and to advance the argument suggesting the dominance of the incumbent in the use of violence to rig elections. With evidence sourced from well-trusted reports from independent election monitors, this paper shows with case studies from Nigeria at different electoral periods that, in terms of influencing election outcomes, the incumbent has been more associated with violence during elections than the opposition. It is further argued in the paper that the existing nature of executive power in Nigeria provides a plausible explanation for the incumbent’s violence during elections.

  16. Measuring set: Reactor Power Meter (type of SG-8), Reactor Energy Meter (type of SG-11) and Digital Dose Meter (type of SG-9) for reactor rigs operation. Zestaw pomiarowy: miernik mocy reaktora (typ SG-8), miernik energii reaktora (typ SG-11) oraz cyfrowy miernik dawki (typ SG-9) dla potrzeb eksploatacji sond reaktorowych

    Energy Technology Data Exchange (ETDEWEB)

    Glowacki, S W

    1982-01-01

    A measuring set consisting of the Reactor Power Meter, Reactor Energy Meter and Digital Dose Meter is described. The gamma radiation of water in the reactor primary cooling circuit reaches the ionisation chamber and involves the output current, driving the Reactor Power Meter and Reactor Energy Meter. The Digital Dose Meter is controlled by the output current of the self-powered detector mounted inside the reactor rig.

  17. Measurement and QCD Analysis of the Diffractive Deep-Inelastic Scattering Cross Section at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Babaev, A.; Backovic, S.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, N.; Bizot, J.C.; Boenig, M.O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J.G.; Coughlan, J.A.; Coppens, Y.R.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; de Boer, Y.; Delcourt, B.; Del Degan, M.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eliseev, A.; Elsen, E.; Essenov, S.; Falkewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Finke, L.; Fleischer, M.; Flucke, G.; Fomenko, A.; Franke, G.; Frisson, T.; Gabathuler, E.; Garutti, E.; Gayler, J.; Gerlich, C.; Ghazaryan, S.; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Grab, C.; Greenshaw, T.; Gregori, M.; Grell, B.R.; Grindhammer, G.; Gwilliam, C.; Haidt, D.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Hussain, S.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, C.L.; Johnson, D.P.; Jung, A.W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I.R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.I.; Lueders, H.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Marage, P.; Marshall, R.; Marti, L.; Martisikova, M.; Martyn, H.U.; Maxfield, S.J.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mladenov, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, M.U.; Muller, K.; Murin, P.; Nankov, K.; Naroska, B.; Naumann, T.; Newman, P.R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Papadopoulou, T.; Pascaud, C.; Patel, G.D.; Peng, H.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Portheault, B.; Povh, B.; Prideaux, P.; Rahmat, A.J.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauter, M.; Sauvan, E.; Schilling, F.P.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.C.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, A.; Steder, M.; Stella, B.; Stiewe, J.; Stoilov, A.; Straumann, U.; Sunar, D.; Tchoulakov, V.; Thompson, G.; Thompson, P.D.; Toll, T.; Tomasz, F.; Traynor, D.; Trinh, T.N.; Truol, P.; Tsakov, I.; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, K.; Urban, M.; Usik, A.; Utkin, D.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vinokurova, S.; Volchinski, V.; Wacker, K.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Wessels, M.; Wessling, B.; Wissing, C.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y.C.; Zimmermann, J.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2006-01-01

    A detailed analysis is presented of the diffractive deep-inelastic scattering process $ep\\to eXY$, where $Y$ is a proton or a low mass proton excitation carrying a fraction $1 - \\xpom > 0.95$ of the incident proton longitudinal momentum and the squared four-momentum transfer at the proton vertex satisfies $|t|<1 {\\rm GeV^2}$. Using data taken by the H1 experiment, the cross section is measured for photon virtualities in the range $3.5 \\leq Q^2 \\leq 1600 \\rm GeV^2$, triple differentially in $\\xpom$, $Q^2$ and $\\beta = x / \\xpom$, where $x$ is the Bjorken scaling variable. At low $\\xpom$, the data are consistent with a factorisable $\\xpom$ dependence, which can be described by the exchange of an effective pomeron trajectory with intercept $\\alphapom(0)= 1.118 \\pm 0.008 {\\rm (exp.)} ^{+0.029}_{-0.010} {\\rm (model)}$. Diffractive parton distribution functions and their uncertainties are determined from a next-to-leading order DGLAP QCD analysis of the $Q^2$ and $\\beta$ dependences of the cross section. The res...

  18. Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.

    Science.gov (United States)

    Glas, Martin; Coch, Christoph; Trageser, Daniel; Dassler, Juliane; Simon, Matthias; Koch, Philipp; Mertens, Jerome; Quandel, Tamara; Gorris, Raphaela; Reinartz, Roman; Wieland, Anja; Von Lehe, Marec; Pusch, Annette; Roy, Kristin; Schlee, Martin; Neumann, Harald; Fimmers, Rolf; Herrlinger, Ulrich; Brüstle, Oliver; Hartmann, Gunther; Besch, Robert; Scheffler, Björn

    2013-06-01

    Cellular heterogeneity, for example, the intratumoral coexistence of cancer cells with and without stem cell characteristics, represents a potential root of therapeutic resistance and a significant challenge for modern drug development in glioblastoma (GBM). We propose here that activation of the innate immune system by stimulation of innate immune receptors involved in antiviral and antitumor responses can similarly target different malignant populations of glioma cells. We used short-term expanded patient-specific primary human GBM cells to study the stimulation of the cytosolic nucleic acid receptors melanoma differentiation-associated gene 5 (MDA5) and retinoic acid-inducible gene I (RIG-I). Specifically, we analyzed cells from the tumor core versus "residual GBM cells" derived from the tumor resection margin as well as stem cell-enriched primary cultures versus specimens without stem cell properties. A portfolio of human, nontumor neural cells was used as a control for these studies. The expression of RIG-I and MDA5 could be induced in all of these cells. Receptor stimulation with their respective ligands, p(I:C) and 3pRNA, led to in vitro evidence for an effective activation of the innate immune system. Most intriguingly, all investigated cancer cell populations additionally responded with a pronounced induction of apoptotic signaling cascades revealing a second, direct mechanism of antitumor activity. By contrast, p(I:C) and 3pRNA induced only little toxicity in human nonmalignant neural cells. Granted that the challenge of effective central nervous system (CNS) delivery can be overcome, targeting of RIG-I and MDA5 could thus become a quintessential strategy to encounter heterogeneous cancers in the sophisticated environments of the brain. Copyright © 2013 AlphaMed Press.

  19. 24 CFR 1000.118 - What recourse does a recipient have if HUD disapproves a proposal to provide assistance to non...

    Science.gov (United States)

    2010-04-01

    ... housing activity? 1000.118 Section 1000.118 Housing and Urban Development Regulations Relating to Housing... § 1000.118 What recourse does a recipient have if HUD disapproves a proposal to provide assistance to non...

  20. Etude expérimentale du séchage convectif à haute température d'un milieu granulaire

    OpenAIRE

    Messai , Souad; Sghaier , Jalila; Lecomte , Didier; Belghith , Ali

    2008-01-01

    International audience; Dans ce travail on présente une étude expérimentale et numérique du séchage convectif à haute température d'un milieu granulaire formé par des particules poreuses sphériques. La partie expérimentale a été consacrée à l'utilisation de l'air humide comme agent séchant. En prenant deux valeurs d'humidité relative de l'air, nous avons mis en évidence l'importance de ce paramètre sur le processus du séchage. Nous avons mesuré simultanément la cinétique de séchage du lit fix...

  1. 30 CFR 250.405 - What are the safety requirements for diesel engines used on a drilling rig?

    Science.gov (United States)

    2010-07-01

    ... engines used on a drilling rig? You must equip each diesel engine with an air take device to shut down the... must equip the engine with an automatic shutdown device; (b) For a diesel engine that is continuously manned, you may equip the engine with either an automatic or remote manual air intake shutdown device; (c...

  2. An improved parametrization and analysis of the EXP3++ algorithm for stochastic and adversarial bandits

    DEFF Research Database (Denmark)

    Seldin, Yevgeny; Lugosi, Gábor

    2017-01-01

    We present a new strategy for gap estimation in randomized algorithms for multiarmed bandits and combine it with the EXP3++ algorithm of Seldin and Slivkins (2014). In the stochastic regime the strategy reduces dependence of regret on a time horizon from $(ln t)^3$ to $(ln t)^2$ and eliminates...

  3. 41 CFR 102-118.420 - Can the Administrator of General Services waive the postpayment auditing provisions of this subpart?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Can the Administrator of General Services waive the postpayment auditing provisions of this subpart? 102-118.420 Section 102-118... Transportation Audits § 102-118.420 Can the Administrator of General Services waive the postpayment auditing...

  4. Biannular Airbreathing Nozzle Rig (BANR) facility checkout and plug nozzle performance test data

    Science.gov (United States)

    Cummings, Chase B.

    2010-09-01

    The motivation for development of a supersonic business jet (SSBJ) platform lies in its ability to create a paradigm shift in the speed and reach of commercial, private, and government travel. A full understanding of the performance capabilities of exhaust nozzle configurations intended for use in potential SSBJ propulsion systems is critical to the design of an aircraft of this type. Purdue University's newly operational Biannular Airbreathing Nozzle Rig (BANR) is a highly capable facility devoted to the testing of subscale nozzles of this type. The high accuracy, six-axis force measurement system and complementary mass flowrate measurement capabilities of the BANR facility make it rather ideally suited for exhaust nozzle performance appraisal. Detailed accounts pertaining to methods utilized in the proper checkout of these diagnostic capabilities are contained herein. Efforts to quantify uncertainties associated with critical BANR test measurements are recounted, as well. Results of a second hot-fire test campaign of a subscale Gulfstream Aerospace Corporation (GAC) axisymmetric, shrouded plug nozzle are presented. Determined test article performance parameters (nozzle thrust efficiencies and discharge coefficients) are compared to those of a previous test campaign and numerical simulations of the experimental set-up. Recently acquired data is compared to published findings pertaining to plug nozzle experiments of similar scale and operating range. Suggestions relating to the future advancement and improvement of the BANR facility are provided. Lessons learned with regards to test operations and calibration procedures are divulged in an attempt to aid future facility users, as well.

  5. 33 CFR 118.85 - Lights on vertical lift bridges.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lights on vertical lift bridges... BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.85 Lights on vertical lift bridges. (a) Lift span lights. The vertical lift span of every vertical lift bridge shall be lighted so that the center of the...

  6. Molecular single-bond covalent radii for elements 1-118.

    Science.gov (United States)

    Pyykkö, Pekka; Atsumi, Michiko

    2009-01-01

    A self-consistent system of additive covalent radii, R(AB)=r(A) + r(B), is set up for the entire periodic table, Groups 1-18, Z=1-118. The primary bond lengths, R, are taken from experimental or theoretical data corresponding to chosen group valencies. All r(E) values are obtained from the same fit. Both E-E, E-H, and E-CH(3) data are incorporated for most elements, E. Many E-E' data inside the same group are included. For the late main groups, the system is close to that of Pauling. For other elements it is close to the methyl-based one of Suresh and Koga [J. Phys. Chem. A 2001, 105, 5940] and its predecessors. For the diatomic alkalis MM' and halides XX', separate fits give a very high accuracy. These primary data are then absorbed with the rest. The most notable exclusion are the transition-metal halides and chalcogenides which are regarded as partial multiple bonds. Other anomalies include H(2) and F(2). The standard deviation for the 410 included data points is 2.8 pm.

  7. Estudo comparativo da resistência do fio de algodão obtido em fiação piloto e em fiação industrial Correlation between laboratory and industrial cotton yarn strength

    Directory of Open Access Journals (Sweden)

    José Fernando Lazzarini

    1972-01-01

    Full Text Available O estudo de 81 pares de valores de resistência do fio de algodão 22/1 produzido em fiação piloto (X e em fiação industrial (Y mostrou que entre os dois processos existe uma correlação r= 0,563**. A equação de regressão é da forma Y= 611,631 + 0,486 X. Ficou demonstrado que equações calculadas para nove linhagens em cada localidade fornecem estimativas mais precisas da resistência do fio do que a equação geral. O coeficiente de correlação mais alto (r=0,924** foi encontrado para a localidade de Campinas.A yarn strength correlation analysis for the 22/1 yarn spun through a Miniature Spinning Plant (X and the yarn of same count spun through an industrial equipment (Y was carried out for 81 pairs of observations. The correlation coeficient between the two processes showed to be r = 0.563 **. The regression equation is of the form: Y = 611.631 + 0.486X. It was showed that the equations to predicted yarn strength, calculated for 9 pairs of values in each location, give better estimations than the general equation calculated for 81 pairs in 9 locations. The highest correlation coefficient (r = 0.944 ** was found for the locality of Campinas.

  8. Hepatocellular carcinoma: a retrospective analysis of 118 cases

    International Nuclear Information System (INIS)

    Aman-ur-Rehman; Murad, S.

    2002-01-01

    Objective: This study aimed at documenting the spectrum of clinico pathological variations in hepatocellular carcinoma (HCC). Design: It was a retrospective study. Place and duration of Study: This study was conducted at the Institute of Nuclear Medicine and Oncology (INMOL) Hospital, Lahore from March 1997 to December 2000. Patients and Methods: The profiles of 118 patients with a biopsy proven hepatocellular carcinoma were analyzed in this period. The data collected was age, sex, clinical presentation and laboratory investigations including liver function tests, alpha fetoprotein and hepatitis profile. Results: Weight loss, jaundice and right upper quadrant abdominal pain were the main presenting symptoms. Out of 118 patients, alpha fetoprotein values were raised in 63(53.38%) patients 106 (89.83%) patients were found to have or have had HBV infections, and 92 (77.96%) patients were anti-HCV positive. Eighty-three (70.33%) patients were cirrhotic. History of alcohol abuse was bound in three patients. Conclusion: The common association of HCC with cirrhosis and hepatitis B and C suggests that vaccination against HBV on nationwide basis can decrease prevalence of this malignancy. There is a need to generate public awareness regarding the transmission of these viruses. Early diagnosis and intervention is also important to the successful management of HCC. (author)

  9. New exact solutions of coupled Boussinesq–Burgers equations by Exp-function method

    Directory of Open Access Journals (Sweden)

    L.K. Ravi

    2017-03-01

    Full Text Available In the present paper, we build the new analytical exact solutions of a nonlinear differential equation, specifically, coupled Boussinesq–Burgers equations by means of Exp-function method. Then, we analyze the results by plotting the three dimensional soliton graphs for each case, which exhibit the simplicity and effectiveness of the proposed method. The primary purpose of this paper is to employ a new approach, which allows us victorious and efficient derivation of the new analytical exact solutions for the coupled Boussinesq–Burgers equations.

  10. 38 CFR 1.18 - Guidelines for establishing presumptions of service connection for former prisoners of war.

    Science.gov (United States)

    2010-07-01

    ... establishing presumptions of service connection for former prisoners of war. 1.18 Section 1.18 Pensions... Guidelines for establishing presumptions of service connection for former prisoners of war. (a) Purpose. The Secretary of Veterans Affairs will establish presumptions of service connection for former prisoners of war...

  11. Heterogenous expression of Pyrus pyrifolia PpCAD2 and PpEXP2 in tobacco impacts lignin accumulation in transgenic plants.

    Science.gov (United States)

    Wang, Yuling; Zhang, Xinfu; Yang, Shaolan; Wang, Caihong; Lu, Guilong; Wang, Ran; Yang, Yingjie; Li, Dingli

    2017-12-30

    Lignin, a natural macromolecular compound, plays an important role in the texture and taste of fruit. Hard end is a physiological disorder of pear fruit, in which the level of lignification in fruit tissues is dramatically elevated. Cinnamyl alcohol dehydrogenase and expansin genes (PpCAD2 and PpEXP2, respectively) exhibit higher levels of expression in 'Whangkeumbae' (Pyrus pyrifolia) pear fruit exhibiting this physiological disorder, relative to control fruit without symptoms. These genes were isolated from pear fruit and subsequently expressed in tobacco (Nicotiana tabacum) to investigate their function. Histochemical staining for lignin revealed that the degree of lignification in leaf veins and stem tissues increased in plants transformed with sense constructs and decreased in plants transformed with antisense constructs of PpCAD2. The expression of native NtCADs was also inhibited in the antisense PpCAD2 transgenic tobacco. Sense and antisense PpCAD2 transgenic tobacco exhibited an 86.7% increase and a 60% decrease in CAD activity, respectively, accompanied by a complementary response in lignin content in root tissues. The basal portion of the stem in PpEXP2 transgenic tobacco was bent and highly lignified. Additionally, the level of cellulose also increased in the stem of PpEXP2 transgenic tobacco. Collectively, these results suggested that PpCAD2 and PpEXP2 genes play a significant role in lignin accumulation in transgenic tobacco plants, and it is inferred that these two genes may also participate in the increased lignification observed in hard end pear fruit. Copyright © 2017. Published by Elsevier B.V.

  12. 0+ analogue state in 118Sb from 117Sn(p,nγ) reaction

    International Nuclear Information System (INIS)

    Pal, J.; Dey, C.C.; Bose, S.; Sinha, B.K.; Chatterjee, M.B.; Mahapatra, D.P.

    1996-01-01

    The analogue of the 0 + ground state in 118 Sn has been observed in the compound nucleus 118 Sb through 117 Sn(p,nγ) 117 Sb reaction. The neutron decays of this analogue resonance have been studied from the deexciting γ-rays of the residual nucleus 117 Sb. From off resonance excitation functions, spin assignments have been made to states in 117 Sb, on the basis of Hauser-Feshbach formalism. The resonance parameters of the isobaric analogue resonance have been determined, including the total, proton and neutron decay widths. (orig.)

  13. High Temperature Dynamic Pressure Measurements Using Silicon Carbide Pressure Sensors

    Science.gov (United States)

    Okojie, Robert S.; Meredith, Roger D.; Chang, Clarence T.; Savrun, Ender

    2014-01-01

    Un-cooled, MEMS-based silicon carbide (SiC) static pressure sensors were used for the first time to measure pressure perturbations at temperatures as high as 600 C during laboratory characterization, and subsequently evaluated in a combustor rig operated under various engine conditions to extract the frequencies that are associated with thermoacoustic instabilities. One SiC sensor was placed directly in the flow stream of the combustor rig while a benchmark commercial water-cooled piezoceramic dynamic pressure transducer was co-located axially but kept some distance away from the hot flow stream. In the combustor rig test, the SiC sensor detected thermoacoustic instabilities across a range of engine operating conditions, amplitude magnitude as low as 0.5 psi at 585 C, in good agreement with the benchmark piezoceramic sensor. The SiC sensor experienced low signal to noise ratio at higher temperature, primarily due to the fact that it was a static sensor with low sensitivity.

  14. Development of a hardware-in-the-loop-test rig to verify the reliability of oil burner pumps. Application by the use of biocide in domestic heating oil; Entwicklung eines Hardware-in-the-loop Pruefstands zum Nachweis der Betriebssicherheit von Oelbrennerpumpen. Anwendungen bei Einsatz von Biozidadditiven

    Energy Technology Data Exchange (ETDEWEB)

    Rheinberg, Oliver van; Lukito, Jayadi; Liska, Martin [Oel-Waerme-Institut gGmbH (OWI), Aachen-Herzogenrath (Germany)

    2009-09-15

    Within this project, a hardware-in-the-loop test rig has been developed to investigate the influence of different fuels on the reliability of oil burner pumps. The test rig is constructed with commercial burner components. One test rig consists of four pump cycles, where the fuel recirculates for max. 2000 h. Low powered electric motors of 90 Watts have been used deliberately, so that the apparatus is more sensitive to failure due to an increase in pump load. A practise relevant intermittent operating mode has been implemented for the simulation of real operation characteristics. The measured variable and evaluation parameters are start-up torque, intake pressure, fuel pump pressure and temperature. Operation failures of oil burner pumps in the field, due to an over-additisation of biocides, have been observed. These failures could be reproducibly simulated on the pump test stands. The results of the project are a redefinition of limits of biocide concentration and the development of new biocides, which are suitable for use in domestic heating oil with a content of up to 20 % Fatty-Acid-Methyl-Ester. (orig.)

  15. Comparative analysis of Nb and Ti addition in the Cu-11,8%wt.Al-0,5%wt.Be e Cu-11,8%wt.Al-3,0%wt.Ni shape memory alloy; Analise comparativa da adicao de NB e TI nas ligas Cu-11,8Al-0,5Be e Cu-11,8Al-3,0Ni passiveis do efeito memoria de forma

    Energy Technology Data Exchange (ETDEWEB)

    Silva Junior, M.Q. da; Oliveira, G.D. de, E-mail: manoel.quirino@ufersa.edu.br [Universidade Federal Rural do Semi-Arido (UFERSA), Mossoro, RN (Brazil)

    2014-07-01

    The system of the Cu-Al alloys shape memory alloy have been the subject of many studies due to a wide range of possible applications and relatively low cost, and the chemical composition of the main factors that determine the properties of these properties. This work analyzed the influence of Nb and Ti elements in Cu-11,8Al-0,5Be and Cu-11,8Al-3,0Ni alloy. The alloys are obtained by melting and passed through homogenizing heat treatment followed by water quenching at 30°C. The samples were characterized by Microscopy Optical, X-ray Diffraction and Microhardness testing. The alloys showed fine precipitates of second phase homogeneously distributed in the matrix that provides improvement in the properties of these alloys. (author)

  16. 17 CFR 1.18 - Records for and relating to financial reporting and monthly computation by futures commission...

    Science.gov (United States)

    2010-04-01

    ... financial reporting and monthly computation by futures commission merchants and introducing brokers. 1.18... UNDER THE COMMODITY EXCHANGE ACT Minimum Financial and Related Reporting Requirements § 1.18 Records for and relating to financial reporting and monthly computation by futures commission merchants and...

  17. An Accurate Redetermination of the $^{118}Sn$ Binding Energy

    CERN Document Server

    Borzakov, S B; Faikow-Stanczyk, H; Grigoriev, Yu V; Panteleev, T; Pospísil, S; Smotritsky, L M; Telezhnikov, S A

    2001-01-01

    The energy of well-known strong {gamma}-line from {{^198}Au}, the "gold standard", has been modified in the light of new adjustments in the fundamental constants and the value of 411.80176(12) keV was determined which is 0.29 eV lower than the latest 1999 value. An energy calibration procedure for determining the neutron binding energy, {B_n}, from complicated {(n , gamma)}-spectra has been developed. A mathematically simple minimization function consisting only of terms having as parameters the coefficients of the energy calibration curve (polynomial) is used. A priori information about the relationships among the energies of different peaks on the spectrum is taking into account by a Monte Carlo simulation. The procedure was used in obtaining of {B_n} for {{^118}Sn} and {{^64}Cu}. The {gamma}-ray spectrum from thermal neutron radiative capture by {{^117}Sn} has been measured on the IBR-2 pulsed reactor. {gamma}-rays were detected by a 72 cm^3 HPGe-detector. {B_n} for {{^64}Cu} was obtained from two {gamma}-...

  18. L’expérience d’une patiente qui reçoit des soins pour la démence

    Science.gov (United States)

    Frank, Christopher; Forbes, Rev Faye

    2017-01-01

    Résumé Objectif Permettre aux médecins de famille de comprendre « l’expérience vécue » de la démence de la bouche d’une personne atteinte de démence—Faye Forbes, ministre anglicane de 64 ans atteinte de la maladie d’Alzheimer, qui donne son point de vue sur comment vivre avec la démence—et utiliser cette information pour améliorer les soins et les résultats. Sources d’information Une recherche a été effectuée dans MEDLINE sur Ovid entre janvier 2005 et février 2015, à l’aide des mots-clés anglais suivants : dementia, caregiver, perspectives et quality of health care. Les articles qui s’adressaient aux médecins de famille ont été sélectionnés. Des revues pertinentes et des articles de recherche originaux ont été utilisés, le cas échéant, s’ils s’appliquaient aux personnes atteintes de démence et à leurs soignants. Message principal Plusieurs cadres de référence organisent les principales expériences décrites par les patients et leurs soignants. Nous avons utilisé une revue de la littérature qualitative pour fournir un cadre de référence résumant l’expérience de Faye, en fonction des thèmes suivants : tenter d’obtenir un diagnostic, accéder au soutien et aux services, besoins en matière d’information, prise en charge de la maladie, et communication et attitudes. Conclusion Les médecins doivent tenir compte de ces thèmes lorsqu’ils planifient la prise en charge des personnes atteintes de démence. Il importe de tenter de comprendre l’expérience et le point de vue des personnes atteintes de démence et de leurs soignants afin de pouvoir dispenser des soins optimaux. PMID:28115451

  19. Étude expérimentale des performances thermiques d’un nanofluide: eau-éthylène-glycol-Al2O3

    Directory of Open Access Journals (Sweden)

    Răzvan-Silviu Luciu

    2007-01-01

    Full Text Available Une nouvelle classe de fluides composée par des nanoparticules métalliques en suspension dans un liquide, appelée nanofluide, est apparue récemment. Quelques études numériques et expérimentales ont montré que ces nouveaux fluides possedent une puissance d’échange thermique remarquable, comparée aux liquides conventionnels. L’étude qui suit a le bout de montrer par voie expérimentale les performances thermiques d’un nanofluide composé d’oxyde d’alumine dispersé dans de l’éthylene-glycol en différentes concentrations, allant de 0 a 2%. Le dispositif expérimental est un échangeur a tubes concentriques en inox, avec écoulement du fluide chaud dans le tube central et du fluide froid dans le tube annulaire. Les résultats obtenus montrent que la présence des nanoparticules dans le fluide de base a pour effet une augmentation considérable du transfert thermique.

  20. Receptor binding proteins of Listeria monocytogenes bacteriophages A118 and P35 recognize serovar-specific teichoic acids

    Energy Technology Data Exchange (ETDEWEB)

    Bielmann, Regula; Habann, Matthias; Eugster, Marcel R. [Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich (Switzerland); Lurz, Rudi [Max-Planck Institute for Molecular Genetics, 14195 Berlin (Germany); Calendar, Richard [Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202 (United States); Klumpp, Jochen, E-mail: jochen.klumpp@hest.ethz.ch [Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich (Switzerland); Loessner, Martin J. [Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich (Switzerland)

    2015-03-15

    Adsorption of a bacteriophage to the host requires recognition of a cell wall-associated receptor by a receptor binding protein (RBP). This recognition is specific, and high affinity binding is essential for efficient virus attachment. The molecular details of phage adsorption to the Gram-positive cell are poorly understood. We present the first description of receptor binding proteins and a tail tip structure for the siphovirus group infecting Listeria monocytogenes. The host-range determining factors in two phages, A118 and P35 specific for L. monocytogenes serovar 1/2 have been determined. Two proteins were identified as RBPs in phage A118. Rhamnose residues in wall teichoic acids represent the binding ligands for both proteins. In phage P35, protein gp16 could be identified as RBP and the role of both rhamnose and N-acetylglucosamine in phage adsorption was confirmed. Immunogold-labeling and transmission electron microscopy allowed the creation of a topological model of the A118 phage tail. - Highlights: • We present the first description of receptor binding proteins and a tail tip structure for the Siphovirus group infecting Listeria monocytogenes. • The host-range determining factors in two phages, A118 and P35 specific for L. monocytogenes serovar 1/2 have been determined. • Rhamnose residues in wall teichoic acids represent the binding ligands for both receptor binding proteins in phage A118. • Rhamnose and N-acetylglucosamine are required for adsorption of phage P35. • We preset a topological model of the A118 phage tail.