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Sample records for mcdonald observatory ids

  1. Supernova observations at McDonald Observatory

    International Nuclear Information System (INIS)

    Wheeler, J.C.

    1984-01-01

    The programs to obtain high quality spectra and photometry of supernovae at McDonald Observatory are reviewed. Spectra of recent Type I supernovae in NGC 3227, NGC 3625, and NGC 4419 are compared with those of SN 1981b in NGC 4536 to quantitatively illustrate both the homogeneity of Type I spectra at similar epochs and the differences in detail which will serve as a probe of the physical processes in the explosions. Spectra of the recent supernova in NGC 0991 give for the first time quantitative confirmation of a spectrally homogeneous, but distinct subclass of Type I supernovae which appears to be less luminous and to have lower excitation at maximum light than classical Type I supernovae

  2. McDONALD OBSERVATORY ARCHIVE OF OPTICAL LINEAR POLARIZATION MEASUREMENTS

    International Nuclear Information System (INIS)

    Wills, Beverley J.; Wills, D.; Breger, M.

    2011-01-01

    We present 990 previously unpublished optical linear polarization measurements of quasars, active galactic nuclei, and some stars observed for interstellar polarization. The observations, covering the period 1981-2000, were made with McDonald Observatory's 2.1 m Struve reflector and the Breger photopolarimeter.

  3. The McDonald Observatory lunar laser ranging project

    Science.gov (United States)

    Silverberg, E. C.

    1978-01-01

    A summary of the activities of the McDonald lunar laser ranging station at Fort Davis for the FY 77-78 fiscal year is presented. The lunar laser experiment uses the observatory 2.7m reflecting telescope on a thrice-per-day, 21-day-per-lunation schedule. Data are recorded on magnetic tapes and sent to the University of Texas at Austin where the data is processed. After processing, the data is distributed to interested analysis centers and later to the National Space Science Data Center where it is available for routine distribution. Detailed reports are published on the McDonald operations after every fourth lunation or approximately once every 115 days. These reports contain a day-by-day documentation of the ranging activity, detailed discussions of the equipment development efforts, and an abundance of other information as is needed to document and archive this important data type.

  4. The night sky brightness at McDonald Observatory

    Science.gov (United States)

    Kalinowski, J. K.; Roosen, R. G.; Brandt, J. C.

    1975-01-01

    Baseline observations of the night sky brightness in B and V are presented for McDonald Observatory. In agreement with earlier work by Elvey and Rudnick (1937) and Elvey (1943), significant night-to-night and same-night variations in sky brightness are found. Possible causes for these variations are discussed. The largest variation in sky brightness found during a single night is approximately a factor of two, a value which corresponds to a factor-of-four variation in airglow brightness. The data are used to comment on the accuracy of previously published surface photometry of M 81.

  5. 2011 Astronomy Day at McDonald Observatory

    Science.gov (United States)

    Preston, Sandra; Hemeway, M.; Wetzel, M.

    2012-01-01

    Our philosophy is that everyday is Astronomy Day because the McDonald Observatory's Frank N. Bash Visitors Center is open 362 days a year. So, how did we create a special celebration for the "Astronomy Day” declared by the Astronomical League? During September 26-29 we conducted 20 videoconferences and served 12,559 students with "Astronomy Day” programming. Connect2Texas provides bridging for a network of Texas-based museums and cultural, historical, and scientific organizations that offer educational content to schools throughout the state via videoconferencing. Connect2Texas connected McDonald Observatory to 334 schools; most of these schools were in Texas, but schools in a dozen other states also participated. While most schools had a "view-only" connection, at least 20 of the schools had interactive connections, whereby the students could ask questions of the presenter. Connect2Texas also collects evaluation information from the participating schools that we will use to produce a report for our funders and make modifications to future programs as need be. The videoconferences were offered free of charge. The theme for the 2011 Astronomy Day program was the Year of the Solar System, which aligns with NASA's theme for 2011 and 2012. By aligning with this NASA theme, we could leverage NASA artwork and materials to both advertise and enrich the learning experience. Videoconference materials also included pre- and post-videoconference assessment sheets, an inquiry based activity, and pre- and post-videoconference activities, all of which were made available online. One of the lessons learned from past Astronomy Day videoconferences is that the days the Astronomical League declares as "Astronomy Day” are not always good days for Texas schools to participate. So, we choose an Astronomy Day that meets the needs of Texas schools and our schedule - so any day can be Astronomy Day. 2011 Astronomy Day was made possible by The Meyer-Levy Charitable Trust.

  6. Thirty years of cometary spectroscopy from McDonald Observatory

    Science.gov (United States)

    Cochran, A. L.; Barker, E. S.; Gray, C. L.

    2012-03-01

    We report on the results of a spectroscopic survey of 130 comets that was conducted at McDonald Observatory from 1980 through 2008. Some of the comets were observed on only one night, while others were observed repeatedly. For 20 of these comets, no molecules were detected. For the remaining 110 comets, some emission from CN, OH, NH, C3, C2, CH, and NH2 molecules were observed on at least one occasion. We converted the observed molecular column densities to production rates using a Haser (Haser, L. [1957]. Liege Inst. Astrophysics Reprint No. 394) model. We defined a restricted data set of comets that had at least three nights of observations. The restricted data set consists of 59 comets. We used ratios of production rates to study the trends in the data. We find two classes of comets: typical and carbon-chain depleted comets. Using a very strict definition of depleted comets, requiring C2and C3 to both be depleted, we find 9% of our restricted data set comets to be depleted. Using a more relaxed definition that requires only C2 to be below a threshold (similar to other researchers), we find 25% of the comets are depleted. Two-thirds of the depleted comets are Jupiter Family comets, while one-third are Long Period comets. 37% of the Jupiter Family comets are depleted, while 18.5% of the Long Period comets are depleted. We compare our results with other studies and find good agreement.

  7. Stellar Radial Velocities with IGRINS at McDonald Observatory

    Science.gov (United States)

    Mace, Gregory; Jaffe, Daniel; Park, Chan; Lee, Jae-Joon

    2016-06-01

    Exoplanet searches with dedicated instrumentation have made 1 m/s radial velocity (RV) precision routine.Yet, RVs for large samples of stars generally remain at the 1km/s level.TheImmersion Grating Infrared Spectrometer (IGRINS) is a revolutionary instrument that exploits broad spectral coverage at high-resolution in the near-infrared.IGRINS on the 2.7 meter Harlan J. Smith Telescope at McDonald Observatory is nearly as sensitive as CRIRES at the 8 meter Very Large Telescope. However, IGRINS at R=45,000 has more than 30 times the spectral grasp of CRIRES.The use of a silicon immersion grating facilitates a compact cryostat while providing simultaneous wavelength coverage from 1.45 - 2.45 microns. Wehave developed a pipeline to cross-correlate the more than 20,000 resolution elements in two IGRINS exposures and provide relative RVs with uncertainties of 50m/s (product for multi-epoch studies of low-mass, stellar and substellar multiplicity.

  8. A continued program of planetary study at the University of Texas McDonald Observatory

    Science.gov (United States)

    Trafton, L.

    1991-01-01

    The program conducts solar system research in support of NASA missions and of general astronomical interest. Investigations of composition, physical characteristics and changes in solar system bodies are conducted primarily using the facilities of McDonald Observatory. Progress, accomplishments, and projected accomplishments are discussed.

  9. Report on the lunar ranging at McDonald Observatory, 1 February - 31 May 1976

    Science.gov (United States)

    Palm, C. S.; Wiant, J. R.

    1976-01-01

    The four spring lunations produced 105 acquisitions, including the 2000th range measurement made at McDonald Observatory. Statistics were normal for the spring months. Laser and electronics problems are noted. The Loran-C station delay was corrected. Preliminary doubles data is shown. New magnetic tape data formats are presented. R and D efforts include a new laser modification design.

  10. MLRS - A lunar/artificial satellite laser ranging facility at the McDonald Observatory

    Science.gov (United States)

    Shelus, P. J.

    1985-01-01

    Experience from lunar and satellite laser ranging experiments carried out at McDonald Observatory has been used to design the McDonald Laser Ranging Station (MLRS). The MLRS is a dual-purpose installation designed to obtain observations from the LAGEOS satellite and lunar targets. The instruments used at the station include a telescope assembly 0.76 meters in diameter; a Q-switched doubled neodymium YAG laser with a pulse rate of three nanoseconds; and a GaAs photodetector with Fabry-Perot interferometric filter. A functional diagram of the system is provided. The operating parameters of the instruments are summarized in a table.

  11. HD 91669B: A NEW BROWN DWARF CANDIDATE FROM THE MCDONALD OBSERVATORY PLANET SEARCH

    International Nuclear Information System (INIS)

    Wittenmyer, Robert A.; Endl, Michael; Cochran, William D.; Ramirez, Ivan; MacQueen, Phillip J.; Shetrone, Matthew; Reffert, Sabine

    2009-01-01

    We report the detection of a brown dwarf candidate orbiting the metal-rich K dwarf HD 91669, based on radial-velocity data from the McDonald Observatory Planet Search. HD 91669b is a substellar object in an eccentric orbit (e = 0.45) at a separation of 1.2 AU. The minimum mass of 30.6M Jup places this object firmly within the brown dwarf desert for inclinations i ∼> 23 0 . This is the second rare close-in brown dwarf candidate discovered by the McDonald planet search program.

  12. The Results of an Era of Teacher Professional Development at McDonald Observatory

    Science.gov (United States)

    Finkelstein, K. D.; Hemenway, M. K.; Preston, S.; Wetzel, M.; Meyer, J.; Rood, M.

    2014-07-01

    During the past decade, McDonald Observatory has been developing and refining its Teacher Professional Development Workshops, many of which have been supported by NASA. Metrics include attendance, perceived knowledge gain, and readiness to apply what was learned in the classroom. Evaluations show impact through the classroom application at five to six months after the workshops and through consistently high positive workshop results. This paper will show that a) our Teacher Professional Development Workshops are consistently well attended, b) the workshops improve teachers' confidence and their understanding of concepts, c) teachers enjoy unique interactions with astronomers and engineers, d) teachers appreciate hands-on and inquiry-based activities that are modeled and tied to state and national standards, and e) many teachers experience using the activities in their classrooms with good results.

  13. Mcdonald Observatory 9P/TEMPEL 1 Data V1.0

    Science.gov (United States)

    Cochran, A. L.; Barker, E. S.; Caballero, M. D.; Gyorgey-Ries, J.

    2010-01-01

    We report on low-spectral resolution observations of comet 9P/Tempel 1 from 1983, 1989, 1994 and 2005 using the 2.7m Harlan J. Smith telescope of McDonald Observatory. This comet was the target of NASA's Deep Impact mission and our observations allowed us to characterize the comet prior to the impact. In the published paper, we showed that the comet decreased in gas production from 1983 to 2005, with the decrease being different factors for different species. OH decreased by a factor 2.7, NH by 1.7, CN by 1.6, C3 by 1.8, CH by 1.4 and C2 by 1.3. Despite the decrease in overall gas production and these slightly different decrease factors, we found that the ratios of the gas production rates of OH, NH, C3, CH and C2 that of CN were constant over all of the apparitions. We saw no change in the production rate ratios after the impact. We found that the peak gas production occurred about two months prior to perihelion. This data set represents the integrated fluxes and column densities, mentioned in the published paper, which were used to derive the production rates in the paper.

  14. McDonald Observatory Planetary Search - A high precision stellar radial velocity survey for other planetary systems

    Science.gov (United States)

    Cochran, William D.; Hatzes, Artie P.

    1993-01-01

    The McDonald Observatory Planetary Search program surveyed a sample of 33 nearby F, G, and K stars since September 1987 to search for substellar companion objects. Measurements of stellar radial velocity variations to a precision of better than 10 m/s were performed as routine observations to detect Jovian planets in orbit around solar type stars. Results confirm the detection of a companion object to HD114762.

  15. A description of the lunar ranging station at McDonald Observatory.

    Science.gov (United States)

    Silverberg, E. C.; Currie, D. G.

    1972-01-01

    The equipment of this station which has been in operation since the deployment of the first corner reflector by the Apollo 11 astronauts. The McDonald 2.7-m telescope is used for both transmission and reception of pulsed ruby laser light during three 45-minute daily laser runs about three weeks in a month. The present laser pulse width, timing system, calibration procedures, and signal levels are designed to achieve ranging with an accuracy to 1 nanosecond. The data rates obtained since September, 1970, are consistent with the scientific commitments of the lunar ranging program. Most of the over 200 acquisitions obtained have an accuracy to better than plus or minus 30 cm. Details of the telescope matching optics, guiding and timing equipment, and calibration procedures are discussed. Representative lunar range data are included.

  16. Activities of the Department of Astronomy and McDonald Observatory of the University of Texas at Austin

    Science.gov (United States)

    Smith, H. J.

    1986-01-01

    McDonald Observatory of the University of Texas at Austin reports on its activities during the period 1 Jan. 1986 to 30 June 1986. Extensive observations of Halley's Comet were obtained. The comet exhibited large variability; moreover, its variability was much more rapid than can be accounted for by water vaporization as the sole controller of activity. Jupiter satellite Io's atmosphere was found to be distended by more than the equilibrium scale height but less than for unimpeded streaming into space. The atmosphere is at least temporarily bound to IO. Uranus' (3-0) H2 quadrupole line shapes require a modification of Baines and Bergstralh's standard model which incorporates at high altitude absorbing haze in addition to the lower haze layer. A fraction of normal H2 equal to 0.25 + or 0.10 is derived, in good agreement with the standard model. This result is unchanged when the preliminary temperature structure derived by the Voyager Radio Occultation Experiment is used instead of Appleby's model c. Out of the six Pluto-Charon mutual events observed this year, data were obtained on four. Preliminary analysis is yielding improved estimates for the diameters, masses, densities, and albedos of these objects.

  17. A Cluster Of Activities On Coma From The Hubble Space Telescope, StarDate, And McDonald Observatory

    Science.gov (United States)

    Hemenway, Mary Kay; Jogee, S.; Fricke, K.; Preston, S.

    2011-01-01

    With a goal of providing a vast audience of students, teachers, the general public, and Spanish-speakers with activities to learn about research on the Coma cluster of galaxies based on the HST ACS Treasury survey of Coma, McDonald Observatory used a many-faceted approach. Since this research offered an unprecedented legacy dataset, part of the challenge was to convey the importance of this project to a diverse audience. The methodology was to create different products for different (overlapping) audiences. Five radio programs were produced in English and Spanish for distribution on over 500 radio stations in the US and Mexico with a listening audience of over 2 million; in addition to the radio listeners, there were over 13,000 downloads of the English scripts and almost 6000 of the Spanish. Images were prepared for use in the StarDate Online Astronomy Picture of the Week, for ViewSpace (used in museums), and for the StarDate/Universo Teacher Guide. A high-school level activity on the Coma Cluster was prepared and distributed both on-line and in an upgraded printed version of the StarDate/Universo Teacher Guide. This guide has been distributed to over 1700 teachers nationally. A YouTube video about careers and research in astronomy using the Coma cluster as an example was produced. Just as the activities were varied, so were the evaluation methods. This material is based upon work supported by the National Aeronautics and Space Administration under Grant/Contract/Agreement No. HST-EO-10861.35-A issued through the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555.

  18. The Coude spectrograph and echelle scanner of the 2.7 m telescope at McDonald observatory

    Science.gov (United States)

    Tull, R. G.

    1972-01-01

    The design of the Coude spectrograph of the 2.7 m McDonald telescope is discussed. A description is given of the Coude scanner which uses the spectrograph optics, the configuration of the large echelle and the computer scanner control and data systems.

  19. Performance of the Zeeman analyzer system of the McDonald Observatory 2.7 meter telescope

    Science.gov (United States)

    Vogt, S. S.; Tull, R. G.; Kelton, P. W.

    1980-01-01

    The paper describes a multichannel photoelectric Zeeman analyzer at the coude spectrograph of the McDonald 2.7 m reflector. A comparison of Lick and McDonald observations of HD 153882 reveals no significant difference in slopes or zero points of the two magnetic fields indicating that the systematic scale difference of 30-40% is probably instrumental in origin. Observations of the magnetic variable beta Cor Bor revealed a more nearly sinusoidal magnetic curve with less internal scatter than the photographically determined field measures of the Lick and Mauna Kea Zeeman systems. Investigation of periodicity in the secularly varying magnetic minima of beta Cor Bor did not yield evidence of previously noted periodicities other than that expected from the time structure of the data sampling.

  20. The high-resolution cross-dispersed echelle white-pupil spectrometer of the McDonald Observatory 2.7-m telescope

    Science.gov (United States)

    Tull, Robert G.; Macqueen, Phillip J.; Sneden, Christopher; Lambert, David L.

    1995-01-01

    A new high-resolution cross-dispersed echelle spectrometer has been installed at the coude focus of the McDonald Observatory 2.7-m telescope. Its primary goal was simultaneously to gather spectra over as much of the spectral range 3400 A to 1 micrometer as practical, at a resolution R identical with lambda/Delta lambda which approximately = 60,000 with signal-to-noise ratio of approximately 100 for stars down to magnitude 11, using 1-h exposures. In the instrument as built, two exposures are all that are needed to cover the full range. Featuring a white-pupil design, fused silica prism cross disperser, and folded Schmidt camera with a Tektronix 2048x2048 CCD used at either of two foci, it has been in regularly scheduled operation since 1992 April. Design details and performance are described.

  1. “An Instrument for the Frontiers of Modern Astronomy”: An Exhibit for the Harlan J. Smith 2.7-m Telescope Lobby at McDonald Observatory

    Science.gov (United States)

    Preston, Sandra; Cianciolo, F.; Jones, T.; Wetzel, M.; Mace, K.; Barrick, R.; Kelton, P.; Cochran, A.; Johnson, R.

    2007-05-01

    Of the 100,000 visitors that come to McDonald Observatory each year, about half of them visit the Harlan J. Smith 2.7-m Telescope. Visitors experience the 2.7-m telescope as part of a guided tour, a self-guided tour, and during the once-a-month special viewing nights, that are unique to a telescope this size. Recent safety requirements limiting visitor access to the dome-floor level and a need to modernize out-of-date displays in the 2.7-m lobby area, motivated us to do this new exhibit. A planning team consisting of McDonald Observatory personnel from Outreach & Education, Physical Plant, and Administration came together via videoconferences (between Austin and Fort Davis) to develop an exhibit for the lobby area of this telescope. As the planning process unfolded, the team determined that a mix of static displays and modern technology such as flat panel displays and DVD video were key to presenting the history of the facility, introducing basic concepts about the telescope and current research, as well as giving virtual access to the dome floor for visitors on the self-guided tour. This approach also allows for content development and much of production to be done in-house, which was important from both a cost and maintenance standpoint. A representative of the Smith family was also consulted throughout the development of the exhibit to insure that the exhibit plan was seen as an acceptable memorial to the late director. The exhibit was installed in January 2007.

  2. Placing the Deep Impact Mission into context: Two decades of observations of 9P/Tempel 1 from McDonald Observatory

    Science.gov (United States)

    Cochran, A. L.; Barker, E. S.; Caballero, M. D.; Györgey-Ries, J.

    2009-01-01

    We report on low-spectral resolution observations of Comet 9P/Tempel 1 from 1983, 1989, 1994 and 2005 using the 2.7 m Harlan J. Smith telescope of McDonald Observatory. This comet was the target of NASA's Deep Impact mission and our observations allowed us to characterize the comet prior to the impact. We found that the comet showed a decrease in gas production from 1983 to 2005, with the decrease being different factors for different species. OH decreased by a factor 2.7, NH by 1.7, CN by 1.6, C 3 by 1.8, CH by 1.4 and C 2 by 1.3. Despite the decrease in overall gas production and these slightly different decrease factors, we find that the gas production rates of OH, NH, C 3, CH and C 2 ratioed to that of CN were constant over all of the apparitions. We saw no change in the production rate ratios after the impact. We found that the peak gas production occurred about two months prior to perihelion. Comet Tempel 1 is a "normal" comet.

  3. THE McDONALD OBSERVATORY PLANET SEARCH: NEW LONG-PERIOD GIANT PLANETS AND TWO INTERACTING JUPITERS IN THE HD 155358 SYSTEM

    International Nuclear Information System (INIS)

    Robertson, Paul; Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Brugamyer, Erik J.; Barnes, Stuart I.; Caldwell, Caroline; Wittenmyer, Robert A.; Horner, J.; Simon, Attila E.

    2012-01-01

    We present high-precision radial velocity (RV) observations of four solar-type (F7-G5) stars—HD 79498, HD 155358, HD 197037, and HD 220773—taken as part of the McDonald Observatory Planet Search Program. For each of these stars, we see evidence of Keplerian motion caused by the presence of one or more gas giant planets in long-period orbits. We derive orbital parameters for each system and note the properties (composition, activity, etc.) of the host stars. While we have previously announced the two-gas-giant HD 155358 system, we now report a shorter period for planet c. This new period is consistent with the planets being trapped in mutual 2:1 mean-motion resonance. We therefore perform an in-depth stability analysis, placing additional constraints on the orbital parameters of the planets. These results demonstrate the excellent long-term RV stability of the spectrometers on both the Harlan J. Smith 2.7 m telescope and the Hobby-Eberly telescope.

  4. Arthur B. McDonald, Physics Nobel Laureate 2015, at CERN colloquium

    CERN Multimedia

    Ordan, Julien Marius

    2017-01-01

    Arthur B. McDonald, Physics Nobel Laureate 2015, photographed at CERN colloquium on the "Science of the Sudbury Neutrino Observatory (SNO) and SNOLAB” given in CERN Main Auditorium on Monday 4 Sep 2017

  5. The McDonaldization of Higher Education.

    Science.gov (United States)

    Hayes, Dennis, Ed.; Wynyard, Robin, Ed.

    The essays in this collection discuss the future of the university in the context of the "McDonaldization" of society and of academia. The idea of McDonaldization, a term coined by G. Ritzer (1998), provides a tool for looking at the university and its inevitable changes. The chapters are: (1) "Enchanting McUniversity: Toward a…

  6. Fast Food McDonald's China Fix

    Institute of Scientific and Technical Information of China (English)

    DAVID HENDRICKSON

    2006-01-01

    @@ Since the opening of its first outlet 16 years ago, McDonald's China operation has on many levels proven enormously successful.Home to more than 750 locations nationwide, the Middle Kingdom today ranks as one of McDonald's ten largest markets,with returns hovering in doubles digits and raking in billions annually. As lucrative as it may be, however, China has nonetheless developed into a relative sore spot for the world's leading fast food giant.

  7. The McDonaldization of Academic Libraries?

    Science.gov (United States)

    Quinn, Brian

    2000-01-01

    Discusses the McDonaldization thesis that suggests that many aspects of the fast food industry are making their way into other areas of society. Explores whether this thesis is applicable to academic libraries, focusing on efficiency, calculability, predictability, control, user expectations, pros and cons of teams, and creativity and information…

  8. McDonald's vs Father Christmas

    Science.gov (United States)

    Pratt, Dave; Simpson, Amanda

    2004-01-01

    Mathematics in textbooks and indeed in conventional classrooms is often presented as exercises or worksheets in which the mathematics itself has been processed into a form that is easily digested. This McDonald's version of mathematics ensures that the mathematical skill or technique is laid bare and typically the sole focus of attention. In this…

  9. McDonald's Recipe for Success

    Science.gov (United States)

    Weinstein, Margery

    2012-01-01

    Who isn't familiar with McDonald's? Its golden arches are among the most recognizable brand icons in the U.S. What many are less familiar with is the methodical and distinguished learning and development that supports that brand. Training that begins by preparing employees to serve customers at the counter, and extends to programs that help…

  10. Pengaruh Terpaan Komunikasi Pemasaran Menu Breakfast Mcdonald"s Keputusan Pembelian

    OpenAIRE

    Tasuki, Martia Mutiara; Pradekso, Tandiyo; Ulfa, Nurist Surayya

    2013-01-01

    PENGARUH TERPAAN KOMUNIKASI PEMASARAN MENU BREAKFAST MCDONALD'S DAN CITRA PRODUK TERHADAP KEPUTUSAN PEMBELIANSkripsiDisusun untuk memenuhi persyaratan menyelesaikanPendidikan Strata IJurusan Ilmu Komunikasi Fakultas Ilmu Sosial dan Ilmu PolitikUniversitas DiponegoroPenyusunNama : Martia Mutiara TasukiNIM : D2C 005 183JURUSAN ILMU KOMUNIKASIFAKULTAS ILMU SOSIAL DAN ILMU POLITIKUNIVERSITAS DIPONEGOROSEMARANG2013PENGARUH TERPAAN KOMUNIKASI PEMASARAN MENU BREAKFAST MCDONALD'S DAN CITRA PRODUK TER...

  11. McDonaldization and Job Insecurity

    OpenAIRE

    Emeka W. Dumbili

    2013-01-01

    The article examines how and why the McDonaldization of banking system in Nigeria engenders job insecurity. This is imperative because it provides an explicit revelation of the root causes of job insecurity in the sector that other scholars have totally omitted. No Nigerian scholar has applied the thesis in relation to job insecurity, which is the major problem in Nigeria’s banking industry. The article based on the an...

  12. Semiotic Analysis Of Mcdonald's Printed Advertisement

    OpenAIRE

    URAIDA, SITI

    2014-01-01

    Keywords: Semiotic, printed advertisement, sign, icon, symbol, index, connotation, myth Printed advertisement has a promotional function as medium to advertise aproduct. It implicitly persuades people to create demand of product which is being advertised. In this study, the writer uses printed advertisement of McDonald's fast food company as the object. The printed advertisement was analyzed by usingSemiotics study. There are seven printed advertisements that were analyzes in this study. All ...

  13. McDonaldization and Job Insecurity

    Directory of Open Access Journals (Sweden)

    Emeka W. Dumbili

    2013-06-01

    Full Text Available The article examines how and why the McDonaldization of banking system in Nigeria engenders job insecurity. This is imperative because it provides an explicit revelation of the root causes of job insecurity in the sector that other scholars have totally omitted. No Nigerian scholar has applied the thesis in relation to job insecurity, which is the major problem in Nigeria’s banking industry. The article based on the analysis of secondary data and observations, therefore, draws on McDonaldization thesis to examine the upsurge of rationalization in the sector since consolidation exercise began in 2005. The article argues that the sector’s rising rationalization and ensuing efficiency, calculability, predictability, and control are necessary. However, these have inevitably engendered job insecurity and its adverse consequences. Based on the critical analyses of available evidence, the article concludes that the best option is to commence resistance of the McDonaldization processes, especially those that replace human with nonhuman technology or make customers unpaid workers.

  14. Improving queuing service at McDonald's

    Science.gov (United States)

    Koh, Hock Lye; Teh, Su Yean; Wong, Chin Keat; Lim, Hooi Kie; Migin, Melissa W.

    2014-07-01

    Fast food restaurants are popular among price-sensitive youths and working adults who value the conducive environment and convenient services. McDonald's chains of restaurants promote their sales during lunch hours by offering package meals which are perceived to be inexpensive. These promotional lunch meals attract good response, resulting in occasional long queues and inconvenient waiting times. A study is conducted to monitor the distribution of waiting time, queue length, customer arrival and departure patterns at a McDonald's restaurant located in Kuala Lumpur. A customer survey is conducted to gauge customers' satisfaction regarding waiting time and queue length. An android app named Que is developed to perform onsite queuing analysis and report key performance indices. The queuing theory in Que is based upon the concept of Poisson distribution. In this paper, Que is utilized to perform queuing analysis at this McDonald's restaurant with the aim of improving customer service, with particular reference to reducing queuing time and shortening queue length. Some results will be presented.

  15. The McDonaldization of Nigerian Universities

    Directory of Open Access Journals (Sweden)

    Emeka W. Dumbili

    2014-04-01

    Full Text Available This article examines the extent to which the deregulation of Nigerian higher education (HE has facilitated the McDonaldization of the universities. University education in Nigeria commenced in 1948 with the establishment of the University College, Ibadan. After independence in 1960, subsequent governments expanded the number of universities, a policy based on a lack of quality manpower in leadership positions created by the exit of British officials and the need to grant access to an increasing number of prospective students. In the 1970s, the number of universities increased accompanied by a decline in infrastructure, funding, and working conditions. This resulted in several strikes and an exodus of academics to other countries. Instead of tackling the problems, the federal government shifted responsibilities by approving private ownership of universities in 1999 and by establishing the National Open University of Nigeria (NOUN in 2001. Against this backdrop, this article critically analyzes how some of these reforms facilitated the McDonaldization of Nigerian universities. The article reveals how this has resulted in an overloading of responsibilities on the faculty, erosion of academic autonomy, a prioritization of quantity over quality of publications, and an assumption of “customer” status by students. The article uses evidence from McDonaldized HE in Western countries to discuss the implications of these developments and suggests some remedial measures.

  16. McDonald 2.1-m and CRTS Photometry of Eclipsing Polars

    Science.gov (United States)

    Wells, Natalie; Mason, Paul

    2018-01-01

    We present broadband optical photometry of five polars made using the 2.1-m telescope of McDonald Observatory. Four of the polars are eclipsing (EP Dra, FL Cet, V2301 Oph, and a Catalina Sky Survey (CSS) polar candidate). In addition, a pre-polar (MQ Dra) was observed. Typical integration times were 1-3 seconds with no dead time. At this time resolution, eclipse structure can be seen in both one- and two-pole accretors. McDonald 2.1-m data over several years is phased together with CSS photometry covering up to 7 years, in search of indications of period variation. Combining the high-resolution, high-speed photometry obtained using the ProEm camera on the McDonald 2.1-m with the sparse, but high-quality multi-year baseline photometry of the CSS places strong constraints on the time variability of the eclipse periods in these binary systems. In most cases, eclipse variations do not perfectly fit a linear ephemeris. We investigate the source of variations using standard O-C diagram techniques and period search algorithms.

  17. Experience in Collaboration: McDenver at McDonald's.

    Science.gov (United States)

    Combs, Clarice Sue

    2002-01-01

    The McDenver at McDonald's project provided a nontraditional, community-based teaching and learning environment for faculty and students in a health, physical education, and recreation (HPER) department and a school of nursing. Children and parents come to McDonald's, children received developmental screenings, and parents completed conferences…

  18. Adolescent Purchasing Behavior at McDonald's and Subway.

    Science.gov (United States)

    Lesser, Lenard I; Kayekjian, Karen C; Velasquez, Paz; Tseng, Chi-Hong; Brook, Robert H; Cohen, Deborah A

    2013-10-01

    To assess whether adolescents purchasing food at a restaurant marketed as "healthy" (Subway) purchase fewer calories than at a competing chain (McDonald's). We studied 97 adolescents who purchased a meal at both restaurants on different days, using each participant as his or her control. We compared the difference in calories purchased by adolescents at McDonald's and Subway in a diverse area of Los Angeles, CA. Adolescents purchased an average of 1,038 calories (standard error of the mean [SEM]: 41) at McDonald's and 955 calories (SEM 39) at Subway. The difference of 83 calories (95% confidence interval [CI]: -20 to 186) was not statistically significant (p = .11). At McDonald's, participants purchased significantly more calories from drinks (151 vs. 61, p McDonald's vs. 35 at Subway, p McDonald's (.15 vs. .57 cups, p McDonald's. Although Subway meals had more vegetables, meals from both restaurants are likely to contribute to overeating. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  19. The McDonald Modified Weibull Distribution: Properties and Applications

    OpenAIRE

    Merovci, Faton; Elbatal, Ibrahim

    2013-01-01

    A six parameter distribution so-called the McDonald modified Weibull distribution is defined and studied. The new distribution contains, as special submodels, several important distributions discussed in the literature, such as the beta modified Weibull, Kumaraswamy modified Weibull, McDonald Weibull and modified Weibull distribution,among others. The new distribution can be used effectively in the analysis of survival data since it accommodates monotone, unimodal and bathtub-shaped hazard fu...

  20. SecurID

    CERN Multimedia

    Now called RSA SecurID, SecurID is a mechanism developed by Security Dynamics that allows two-factor authentication for a user on a network resource. It works on the principle of the unique password mode, based on a shared secret. Every sixty seconds, the component generates a new six-digit token on the screen. The latter comes from the current time (internal clock) and the seed (SecurID private key that is available on the component, and is also from the SecurID server). During an authentication request, the SecurID server will check the entered token by performing exactly the same calculation as that performed by your component. The server knows the two information required for this calculation: the current time and the seed of your component. Access is allowed if the token calculated by the server matches the token you specified.

  1. McDonaldization, Islamic teachings, and funerary practices in Kuwait.

    Science.gov (United States)

    Iqbal, Zafar

    2011-01-01

    Drawing on George Ritzer's sociological concept of McDonaldization, this article explores the transformation of burial practices in Kuwait. It is argued that traditional, religious, and private ways of dealing with death have been modernized using the fast-food model of McDonald's. This article examines Islamic teachings on burial and how that model has been applied to the traditional Muslim funerary services, including cemetery management, grave excavation, funeral prayers, burial, and condolences, to make them more efficient vis-a-vis more profitable. Based on personal observations and random interviews, the study finds that the state bureaucracy in Kuwait has made burial rituals more efficient, standardized, calculable, and controlled. Furthermore, several associated irrationalities are also considered. Findings suggest that some individuals may not be happy with these changes but there is no popular resistance to McDonaldization of the burial practices, probably due to the authoritarian and welfare nature of the State of Kuwait.

  2. McDonald and Company Securities Library User Survey, 1996.

    Science.gov (United States)

    Wolfgram, Derek E.

    The library of McDonald and Company Securities is important to the success of the business and its employees. This study assesses the needs and expectations of the library users, and analyzes how well the current library services are meeting those needs and expectations. A questionnaire was distributed to a large random sample of the firm's…

  3. Training for QSC: How McDonald's Makes Library Managers.

    Science.gov (United States)

    Aycock, Anthony

    2001-01-01

    Written by a former McDonald's manager who earned a master's degree in library science, this article describes how "QSC"--quality, services, and cleanliness--can be applied to libraries in the same way it is used by restaurants. Argues that libraries are simply businesses that cater to customers. (Contains 42 references.) (NB)

  4. Bridge Suture for Successful McDonald Emergency Cerclage.

    Science.gov (United States)

    Tanaka, Masaaki; Hori, Yoshiaki; Shirafuji, Aya; Kato, Mitsunori; Kato, Jyun; Kobayashi, Hiroto; Tsuchida, Toru; Fukae, Tsukasa

    2017-01-01

    To create awareness about a surgical technique termed bridge suture, which is performed as a pretreatment before a McDonald cerclage is performed on an emergency to treat severe cervical insufficiency. Procedures for bridge suture were reviewed in detail and outcomes of 16 patients treated with bridge suture followed by McDonald cerclage were evaluated retrospectively. Using the bridge suture, the edges of uterine cervix were temporarily sutured and the external uterine os was closed, while the hourglass-shaped fetal membranes were concomitantly confined within the cervix; subsequently, a McDonald cerclage was performed. Over a 22-year period, 16 patients with a dilated cervix and bulging fetal membranes were treated using the technique of bridge suture followed by an emergency cerclage. The mean gestational age at cerclage was 22.5 weeks; the mean gestational age at delivery was 30.7 weeks; and the mean interval between cerclage and delivery was 8.2 weeks. In 15 out of 16 cases, cerclage was performed without encountering any complications. No maternal complications, including cervical laceration, were observed. The mean body weight of 17 neonates, including that of a twin, was 1,516 g and of them, 15 neonates survived. The important outcome of bridge suture is the replacement of fetal membranes back into the uterine cavity before McDonald's cerclage is performed. Pretreatment with bridge suture may facilitate the performance of a successful emergency cerclage and contribute to good maternal and neonatal outcomes. © 2016 S. Karger AG, Basel.

  5. Continued program of planetary study at the University of Texas McDonald Observatory

    International Nuclear Information System (INIS)

    Smith, H.J.; Barker, E.S.; Cochran, W.D.; Trafton, L.M.

    1986-01-01

    The beginning of eclipses of the Pluto-Charon system was detected. The onset of coma formation of P/Halley at 5.4 au was detected and evidence of sublimation at 4.8 au when CN emission was detected. Extensive spatial maps of the gas in the comae of comets Halley and Giacobini-Zinner were obtained in fall 1985. Halley was time variable, and Giacobini-Zinner was depleted in C 2 and C 3 relative to CN. Comet Kopff was shown to have a pre-perihelion brightness maximum of its gas, consistent with mantle development if the comet is a high obliquity object. New Haser model scale lengths for CN, C 3 , and C 2 were determined using results from the Faint Comet Survey. Spectra of 12 asteroids in unusual orbits showed no evidence of any comet-like emission features. In particular, 3200 Phaethon (1983 TB) has no gas or dust coma, in spite of the similarity of its orbit with the Geminid meteor stream. Data were analyzed on Saturn's H 2 and CH 4 bands for the recent southern summer using a Tomasko-Doose type of haze distribution. This haze model fits the data moderately well, giving a CH 4 mixing ratio of (4.2 + or 0.4)x003. Simple functions were found to approximate the collision-induced rotation-translation thermal opacity of H 2

  6. Observations of faint comets at McDonald Observatory: 1978-1980

    Science.gov (United States)

    Barker, E. S.; Cochran, A. L.; Rybski, P. M.

    1981-01-01

    Modern observational techniques, developed for spectroscopy and photometry of faint galaxies and quasars, successfully applied to faint comets on the 2.7 m telescope. The periodic comets Van Biesbrock, Ashbrook-Jackson, Schwassmann-Wachmann 1, Tempel 2, Encke, Forbes, Brooks 2, Stephan-Oterma and the new comets Bradfield (19791), Bowell (1980b), Chernis-Petrauskas (1980k) were observed. The comets ranged in magnitude from 10th to 20th magnitude. For comets fainter than 19th magnitude, reflectance spectra at 100A resolution and area photometry were obtained. On comets of 17th or 18th magnitude, spectrometric scans (6A resolution) of the nucleus or inner coma region. On those comets which are brighter than 16th magnitude spatial spectrophotometric (6A resolution) studies of the inner and extended comae were done. An extensive spatial study of the comae of P/Encke and P/Stephen-Oterma, correlated with heliocentric distance is taking place. The observing process used is described and examples of the results obtained to date are discussed.

  7. Astrometric observations of Saturn's satellites from McDonald Observatory, 1972. [using reference stars

    Science.gov (United States)

    Abbot, R. I.; Mulholland, J. D.; Shelus, P. J.

    1974-01-01

    Observations of Saturn's satellites were reduced by means of secondary reference stars obtained by reduction of Palomar Sky Survey (PSS) plates. This involved the use of 39 SAO stars and plate overlap technique to determine the coordinates of 59 fainter stars in the satellite field. Fourteen plate constants were determined for each of the two PSS plates. Comparison of two plate measurement and reduction techniques on the satellite measurements demonstrate the existence of a serious background gradient effect and the utility of microdensitometry to eliminate this error source in positional determinations of close satellites.

  8. The McDonald Observatory Faint Comet Survey - Gas production in 17 comets

    Science.gov (United States)

    Cochran, Anita L.; Barker, Edwin S.; Ramseyer, Tod F.; Storrs, Alex D.

    1992-01-01

    The complete Intensified Dissector Scanner data set on 17 comets is presented, and production rates are derived and analyzed. It is shown that there is a strong degree of homogenization in the production rate ratios of many comets. It also appears that the ratio of the production rates of the various species has no heliocentric distance dependence, except for the case of NH2. When speaking of the gas in the coma of a comet, it appears that comets must have been formed under remarkably uniform conditions, and that they must have evolved and formed their comae in a similar manner. The data presented here constitute strong evidence that the minor species must be bound up in a lattice and that the interior of a comet must be reasonably uniform.

  9. Extending the McDonald Observatory Serendipitous Survey of UV/Blue Asteroid Spectra

    Science.gov (United States)

    Vilas, Faith; Cochran, A. L.

    1999-01-01

    Moderate resolution asteroid spectra in the 350 - 650 nm spectral range acquired randomly over many years (Cochran and Vilas, Icarus v 127, 121, 1997) identified absorption features in spectra of some of the asteroids. A feature centered at 430 nm was identified in the spectra of some low-albedo asteroids (C class and subclass), similar to the feature identified by Vilas et al. (Icarus, v. 102, 225,1993) in other low-albedo asteroid spectra and attributed to a ferric iron spin-forbidden transition in iron alteration minerals such as jarosite. Features at 505 nm and 430 nm were identified in the spectrum of 4 Vesta. The 505-nm feature is highly diagnostic of the amount and form of calcium in pyroxenes. This suggested further research on the sharpness and spectral placement of this feature in the spectra of Vesta and Vestoids (e.g., Cochran and Vilas, Icarus v. 134, 207, 1998). In 1997 and 1998, additional UV/blue spectra were obtained at the 2.7-m Harlan J. Smith telescope with a facility cassegrain spectrograph. These included spectra of low-albedo asteroids, the R-class asteroid 349 Dembowska, and the M-class asteroid 135 Hertha. These spectra will be presented and identified features will be discussed.

  10. Report on the lunar ranging at McDonald Observatory. [spark gap configuration and photomultiplier system

    Science.gov (United States)

    Silverberg, E. C.

    1977-01-01

    Range measurements to an accuracy of 5 cm were achieved following improvements in the laser oscillator configuration and the photomultiplier system. Modifications to the laser include a redesigned pockel cell mount to eliminate stressing of the cell crystal; an improved electrically triggered spark gap for sharpening the electrical pulse; the use of a brewster plate in the cavity to eliminate pre-pulsing; improved alignment for the oscillator system; and increased cavity lifetime through thin film polarizer technology. Laser calibration data are presented along with the lunar laser operations log for June to October 1977.

  11. Astrometric observations of Saturn's satellites from McDonald Observatory, 1972

    Science.gov (United States)

    Abbot, R. I.; Mulholland, J. D.; Shelus, P. J.

    1975-01-01

    Observations of Saturn's satellites have been reduced by means of secondary reference stars obtained by reduction of Palomar Sky Survey plates. This involved the use of 29 SAO stars and plate overlap technique to determine the coordinates of 59 fainter stars in the satellite field. Fourteen plate constants were determined for each of the two PSS plates. Comparison of two plate measurement and reduction techniques on the satellite measures appears to demonstrate the existence of a serious background gradient effect and the utility of microdensitometry to eliminate this error source in positional determinations of close satellites.

  12. Interoperability for electronic ID

    OpenAIRE

    Zygadlo, Zuzanna

    2009-01-01

    Electronic Business, including eBanking, eCommerce and eGovernmental services, is today based on a large variety of security solutions, comprising electronic IDs provided by a broad community of Public Key Infrastructure (PKI) vendors. Significant differences in implementations of those solutions introduce a problem of lack of interoperability in electronic business, which have not yet been resolved by standardization and interoperability initiatives based on existing PKI trust models. It i...

  13. FlowIDS

    OpenAIRE

    Sabolčák, Peter

    2006-01-01

    FlowIDS is system which can detect some of the undesirable traffi c in computer networks (undesirable traffic could be also ie. virus activity or overloading of network) and mostly doing counteraction which are set by administrator. Information about data ows are provided by hardware of network infrastructure, eliminitaion of undesirable activity is done through changes in network hardware settings. Regarding the quantity of solution which are provided on market, I decided to focus on Cisco n...

  14. Vnímanie značky McDonald's na českom trhu

    OpenAIRE

    Harčár, Tomáš

    2015-01-01

    The bachelor thesis explores perception of the brand McDonald's on the Czech market. The objective of this thesis is to test via questionnaire an assumption, which is based on belief that customers find food sold in McDonald's restaurant unhealthy and of poor quality. The thesis contains a theoretic part which presents a basic definition linked to brand building and brand image. Those definitions are further used to explain advertising strategy of McDonald's company. Concluding chapter evalua...

  15. Comparative Study of McDonald's and Kentucky Fried Chicken (KFC) development in China

    OpenAIRE

    Xie, Yuanyuan; Hu, Wei

    2013-01-01

    Abstract McDonald's and KFC are two international fast food restaurants. They both expended their businesses in global scale. It is obvious that McDonald surpassed KFC in terms of sales and fame in international level. However, in China, KFC performs better than McDonald's. The aim of this study is to find out how these two companies developed differently in Chinese market. By making a comparative study of McDonald's and KFC, different operation and competitive strategy theory will be...

  16. LASSO observations at McDonald and OCA/CERGA: A preliminary analysis

    Science.gov (United States)

    Veillet, CH.; Fridelance, P.; Feraudy, D.; Boudon, Y.; Shelus, P. J.; Ricklefs, R. L.; Wiant, J. R.

    1993-01-01

    The Laser Synchronization from Synchronous Orbit (LASSO) observations between USA and Europe were made possible with the move of Meteosat 3/P2 toward 50 deg W. Two Lunar Laser Ranging stations participated into the observations: the MLRS at McDonald Observatory (Texas, USA) and OCA/CERGA (Grasse, France). Common sessions were performed since 30 Apr. 1992, and will be continued up to the next Meteosat 3/P2 move further West (planned for January 1993). The preliminary analysis made with the data already collected by the end of Nov. 1992 shows that the precision which can be obtained from LASSO is better than 100 ps, the accuracy depending on how well the stations maintain their time metrology, as well as on the quality of the calibration (still to be made.) For extracting such a precision from the data, the processing has been drastically changed compared to the initial LASSO data analysis. It takes into account all the measurements made, timings on board, and echoes at each station. This complete use of the data increased dramatically the confidence into the synchronization results.

  17. McDonald Generalized Linear Failure Rate Distribution

    Directory of Open Access Journals (Sweden)

    Ibrahim Elbatal

    2014-10-01

    Full Text Available We introduce in this paper a new six-parameters generalized version of the generalized linear failure rate (GLFR distribution which is called McDonald Generalized Linear failure rate (McGLFR distribution. The new distribution is quite flexible and can be used effectively in modeling survival data and reliability problems. It can have a constant, decreasing, increasing, and upside down bathtub-and bathtub shaped failure rate function depending on its parameters. It includes some well-known lifetime distributions as special sub-models. Some structural properties of the new distribution are studied. Moreover we discuss maximum likelihood estimation of the unknown parameters of the new model.

  18. The Mcdonaldization of Academic Libraries and the Values of Transformational Change

    Science.gov (United States)

    Nicholson, Karen P.

    2015-01-01

    In his article "The McDonaldization of Academic Libraries?" Brian Quinn explores to what extent and to what effect academic libraries have become "McDonaldized," according to the concept developed by sociologist George Ritzer. Quinn identifies a number of ways in which the four dimensions of…

  19. Hesburger asub ründama, McDonalds teeb kaevikuid / Andres Reimer

    Index Scriptorium Estoniae

    Reimer, Andres

    2005-01-01

    Hesburger tahab Eestis oma restoranide hulka kolmekordistada. McDonald's Eestis ei laiene, kuid kavatseb ettevõtte efektiivsust suurendada. Eesti hamburgerirestoranide kett Nehatu on konkurentsist välja langenud. Tabelid: Tulemused; Hamburgerirestoranid Eestis; Hamburger ja McDonald's maailmas. Lisad: Hakkas Hesburgeri partneriks; Hakka McDonald'si partneriks

  20. A Comparative Study of McDonald's Wedding Narratives with the Model of Anchoring

    Science.gov (United States)

    Huang, Mimi

    2016-01-01

    Fast-food giant McDonald's announced in 2010 that they would start hosting wedding ceremonies and receptions for couples who would like to get married in their restaurants in Hong Kong. This paper conducts a study comparing the differing representations of McDonald's wedding services through a narrative analytical approach. Specifically, this…

  1. Corporate communication or McCommunication? Considering a McDonaldization of corporate communication hypothesis

    NARCIS (Netherlands)

    Verhoeven, P.

    2015-01-01

    In this essay the perspective of Ritzer's McDonaldization of Society Thesis is the starting point for developing hypotheses about corporate communication (CorpCom). The central idea of McDonaldization is that increasing numbers of organizations are run as fast food restaurants, focusing on:

  2. Potential effects of the next 100 billion hamburgers sold by McDonald's.

    Science.gov (United States)

    Spencer, Elsa H; Frank, Erica; McIntosh, Nichole F

    2005-05-01

    McDonald's has sold >100 billion beef-based hamburgers worldwide with a potentially considerable health impact. This paper explores whether there would be any advantages if the next 100 billion burgers were instead plant-based burgers. Nutrient composition of the beef hamburger patty and the McVeggie burger patty were obtained from the McDonald's website; sales data were obtained from the McDonald's customer service. Consuming 100 billion McDonald's beef burgers versus the same company's McVeggie burgers would provide, approximately, on average, an additional 550 million pounds of saturated fat and 1.2 billion total pounds of fat, as well as 1 billion fewer pounds of fiber, 660 million fewer pounds of protein, and no difference in calories. These data suggest that the McDonald's new McVeggie burger represents a less harmful fast-food choice than the beef burger.

  3. Ronald McDonald dit: "Tout le monde connait: 'Deuxsteakshachessaucespecialesaladefromageoignons dansuntriplepainrondrecouvertdegrainsdesesames'" (Ronald McDonald Says: "Everyone Knows: 'Two-All-Beef-Patties-Special-Sauce-Lettuce-Cheese-Pickles- Onions-on-a-Sesame-Seed Bun'").

    Science.gov (United States)

    Headrick, Robert J., Jr.

    This booklet is intended for classroom use in first-year high school French to acquaint students with the McDonald's fast food restaurants in Paris. The specific objectives are for the student to: (1) discuss the similarities and differences between the American and Parisian McDonald's, (2) set up a miniature McDonald's in the classroom, (3) order…

  4. Ronald McDonald pregunta: "Puedes decir: 'dostortosdepurocarnederessalsaespeciallechugagueso- pepinillosycebollasenunpanconsemillasdeajonjoli'?" (Ronald McDonald Asks: "Can You Say: 'Two-All-Beef-Patties-Special-Sauce-Lettuce-Cheese-Pickles-Onions-On- A-Sesame-Seed-Bun'?" Activities in Spanish).

    Science.gov (United States)

    Headrick, Robert J., Jr.

    This booklet is intended for classroom use in first-year high school Spanish to acquaint students with the McDonald's fast food restaurants in Costa Rica. The specific objectives are for the student to: (1) discuss the similarities and differences between the American and Costa Rican McDonald's, (2) set up a miniature McDonald's in the classroom,…

  5. Facts about Infectious Diseases (ID)

    Science.gov (United States)

    ... an ID Specialist? Facts about ID Pocketcard Infectious diseases are caused by microscopic organisms that penetrate the body’s natural ... from diseases such as AIDS or treatment of diseases such as cancer, may allow ... of contaminated food or water, bites from vectors such as ticks or mosquitoes ...

  6. [The dangers and drifts of health McDonaldization].

    Science.gov (United States)

    Cembrani, Fabio

    2016-01-01

    The author reflects on the healthcare crisis, starting from globalization and liquid-modern society, with its systemic contradictions. The health care system is influenced by McDonald's success and its philosophy: efficiency, productivity, cost reduction, procedural standardization and control. This article underlines the deficiencies and manipulations in the health care system. The profit-oriented economic model is successful due to lack of attention to product quality from the globalised and hyper-consumerist society. Italian legislation has regulated the standardization in healthcare procedure, aiming at cost reduction of defensive medicine. It has been underlined that it defines actions, nevertheless human activity is mainly realized through language, gesture and creation. A new anthropological model is proposed, based on commitment and distributive justice.

  7. Reliability and validity of the McDonald Play Inventory.

    Science.gov (United States)

    McDonald, Ann E; Vigen, Cheryl

    2012-01-01

    This study examined the ability of a two-part self-report instrument, the McDonald Play Inventory, to reliably and validly measure the play activities and play styles of 7- to 11-yr-old children and to discriminate between the play of neurotypical children and children with known learning and developmental disabilities. A total of 124 children ages 7-11 recruited from a sample of convenience and a subsample of 17 parents participated in this study. Reliability estimates yielded moderate correlations for internal consistency, total test intercorrelations, and test-retest reliability. Validity estimates were established for content and construct validity. The results suggest that a self-report instrument yields reliable and valid measures of a child's perceived play performance and discriminates between the play of children with and without disabilities. Copyright © 2012 by the American Occupational Therapy Association, Inc.

  8. Assessing the health impact of transnational corporations: a case study on McDonald's Australia.

    Science.gov (United States)

    Anaf, Julia; Baum, Frances E; Fisher, Matt; Harris, Elizabeth; Friel, Sharon

    2017-02-06

    The practices of transnational corporations affect population health through production methods, shaping social determinants of health, or influencing the regulatory structures governing their activities. There has been limited research on community exposures to TNC policies and practices. Our pilot research used McDonald's Australia to test methods for assessing the health impacts of one TNC within Australia. We adapted existing Health Impact Assessment methods to assess McDonald's activities. Data identifying potential impacts were sourced through document analysis, including McDonald's corporate literature; media analysis and semi-structured interviews. We commissioned a spatial and socioeconomic analysis of McDonald's restaurants in Australia through Geographic Information System technology. The data was mapped against a corporate health impact assessment framework which included McDonald's Australia's political and business practices; products and marketing; workforce, social, environmental and economic conditions; and consumers' health related behaviours. We identified both positive and detrimental aspects of McDonald's Australian operations across the scope of the CHIA framework. We found that McDonald's outlets were slightly more likely to be located in areas of lower socioeconomic status. McDonald's workplace conditions were found to be more favourable than those in many other countries which reflects compliance with Australian employment regulations. The breadth of findings revealed the need for governments to strengthen regulatory mechanisms that are conducive to health; the opportunity for McDonald's to augment their corporate social responsibility initiatives and bolster reputational endorsement; and civil society actors to inform their advocacy towards health and equity outcomes from TNC operations. Our study indicates that undertaking a corporate health impact assessment is possible, with the different methods revealing sufficient information to

  9. Postavení firmy McDonald's na trhu v USA

    OpenAIRE

    Holkupová, Jitka

    2012-01-01

    This thesis deals with McDonald's and its current position in the U.S. market. The first chapter focuses on the company's history from the very beginnings to the present. It explains what was behind the success of McDonald's and how the company is different from most competitors. The second chapter focuses on the current situation in the U.S. market, the role of franchising in the fast food industry and McDonald's compared with its main competitors. The subject of the third chapter is the SWO...

  10. Private Observatories in South Africa

    Science.gov (United States)

    Rijsdijk, C.

    2016-12-01

    Descriptions of private observatories in South Africa, written by their owners. Positions, equipment descriptions and observing programmes are given. Included are: Klein Karoo Observatory (B. Monard), Cederberg Observatory (various), Centurion Planetary and Lunar Observatory (C. Foster), Le Marischel Observatory (L. Ferreira), Sterkastaaing Observatory (M. Streicher), Henley on Klip (B. Fraser), Archer Observatory (B. Dumas), Overbeek Observatory (A. Overbeek), Overberg Observatory (A. van Staden), St Cyprian's School Observatory, Fisherhaven Small Telescope Observatory (J. Retief), COSPAR 0433 (G. Roberts), COSPAR 0434 (I. Roberts), Weltevreden Karoo Observatory (D. Bullis), Winobs (M. Shafer)

  11. European Southern Observatory

    CERN Multimedia

    CERN PhotoLab

    1970-01-01

    Professor A. Blaauw, Director general of the European Southern Observatory, with George Hampton on his right, signs the Agreement covering collaboration with CERN in the construction of the large telescope to be installed at the ESO Observatory in Chile.

  12. Market Entry Strategies : Case: McDonald's entry on the Russian market

    OpenAIRE

    Karataev, Oleg

    2015-01-01

    The thesis considers the entry strategy and development of the company McDonald's into international markets. The theoretical aspects of the entry strategy of the company into the international markets. Analyzes the key features of the development of McDonald's in Russia. Investigated the prospects of the company in international markets. In theoretic part there was regarded some important aspects of international strategic management, such as: strategic alternatives, elements and levels o...

  13. Evaluation of the 2010 McDonald multiple sclerosis criteria in children with a clinically isolated syndrome.

    Science.gov (United States)

    Kornek, Barbara; Schmitl, Beate; Vass, Karl; Zehetmayer, Sonja; Pritsch, Martin; Penzien, Johann; Karenfort, Michael; Blaschek, Astrid; Seidl, Rainer; Prayer, Daniela; Rostasy, Kevin

    2012-12-01

    Magnetic resonance imaging diagnostic criteria for paediatric multiple sclerosis have been established on the basis of brain imaging findings alone. The 2010 McDonald criteria for the diagnosis of multiple sclerosis, however, include spinal cord imaging for detection of lesion dissemination in space. The new criteria have been recommended in paediatric multiple sclerosis. (1) To evaluate the 2010 McDonald multiple sclerosis criteria in children with a clinically isolated syndrome and to compare them with recently proposed magnetic resonance criteria for children; (2) to assess whether the inclusion of spinal cord imaging provided additional value to the 2010 McDonald criteria. We performed a retrospective analysis of brain and spinal cord magnetic resonance imaging scans from 52 children with a clinically isolated syndrome. Sensitivity, specificity and accuracy of the magnetic resonance criteria were assessed. The 2010 McDonald dissemination in space criteria were more sensitive (85% versus 74%) but less specific (80% versus 100%) compared to the 2005 McDonald criteria. The Callen criteria were more accurate (89%) compared to the 2010 McDonald (85%), the 2005 McDonald criteria for dissemination in space (81%), the KIDMUS criteria (46%) and the Canadian Pediatric Demyelinating Disease Network criteria (76%). The 2010 McDonald criteria for dissemination in time were more accurate (93%) than the dissemination in space criteria (85%). Inclusion of the spinal cord did not increase the accuracy of the McDonald criteria.

  14. The occultation of Epsilon Geminorum by Mars - Analysis of McDonald data. [turbulent scintillation in light curves

    Science.gov (United States)

    Africano, J.; De Vaucouleurs, G.; Evans, D. S.; Finkel, B. E.; Nather, R. E.; Palm, C.; Silverberg, E.; Wiant, J.; Hubbard, W. B.; Jokipii, J. R.

    1977-01-01

    An analysis of observations of the occultation of Epsilon Gem by Mars on April 8, 1976, is presented. The data were obtained by three neighboring telescopes at McDonald Observatory. Intensity fluctuations on time scales of the order of 100 ms were observed simultaneously at the three telescopes. As the observations compare well with predictions of turbulent scintillation theory, it is concluded that such fluctuations were probably largely the effect of stellar scintillations in the Martian atmosphere. The stellar diameter is included as a parameter in the theory but in a way which differs from previously published interpretations of occultations of extended sources by planetary atmospheres. Scintillations govern the experimental uncertainty in the deduction of the scale height of the high Martian atmosphere. A density scale height of 9.9 + or - 2.5 km is obtained at an altitude of 74 + or - 8 km above the mean surface. For CO 2 gas, this result corresponds to a temperature of 190 + or - 50 K.

  15. Interobserver agreement on Poser's and the new McDonald's diagnostic criteria for multiple sclerosis.

    Science.gov (United States)

    Zipoli, V; Portaccio, E; Siracusa, G; Pracucci, G; Sorbi, S; Amato, M P

    2003-10-01

    We assessed the interobserver agreement on the diagnosis of multiple sclerosis (MS) in a study sample consisting of 41 MS (15 relapsing remitting, two secondary progressive, five primary progressive and 19 presenting their first clinical attack) and three non-MS cases. Clinical and paraclinical information was recorded in standardized forms. Four neurologists were asked to make a diagnosis using Poser's and McDonald's criteria and to assess MRI scans according to the McDonald's guidelines. In terms of the kappa statistic (kappa), we found a moderate agreement on the overall diagnosis using both Poser's and McDonald's criteria (kappa, respectively 0.57 and 0.52). As for distinct diagnostic categories, we observed a moderate to substantial agreement for the three McDonald categories (range of kappa values 0.49-0.64) and a fair to substantial agreement for the nine Poser categories (range of kappa values 0.37-0.67). Taking into account clinical information, the agreement on dissemination over time was substantially higher (kappa = 0.69) than that found on dissemination over space (kappa = 0.46). In contrast, for MRI assessment, the agreement for spatial dissemination was substantial (kappa = 0.74) compared with the fair agreement (kappa = 0.25) yielded by dissemination over time. The new McDonald's criteria yield a good overall diagnostic reliability, and compare favourably with Poser's classification in terms of agreement on distinct diagnostic categories.

  16. Ilusões de modernidade: o fetiche da marca McDonald's no Brasil Illusions of modernity: the fetish of McDonald's' brand in Brazil

    Directory of Open Access Journals (Sweden)

    Isleide Arruda Fontenelle

    2006-08-01

    Full Text Available Objetiva-se apresentar e discutir as relações atuais entre imagem e entretenimento a partir de pesquisas realizadas sobre a construção da imagem de marca McDonald's e sobre as modernas técnicas de marketing. Visando compreender porque nos tornamos consumidores de imagens, procurou-se recuperar, a partir da própria historia do McDonald's, os acontecimentos econômicos, sociais, culturais, políticos, que teriam nos transformado em uma sociedade na qual "estar na imagem é existir". Embora trágica em seu sentido de fundo, essa perda da forma nos é compensada por imagens de diversão e felicidade que as marcas nos transmitem. Ao final, questiona-se o alcance global dessa promessa a partir de uma digressão sobre o Brasil: como a marca McDonald's nos fornece as imagens para uma certa constituição identitária; e o seu nome para um sentimento de permanência? Como falar de "identificação" com uma marca que, aparentemente, não teria uma relação histórica e cultural com o Brasil?This article presents and discusses the current relationship between image and entertainment, based on the results of research studies on the constitution of McDonald's' brand image all over the world and contemporary marketing. Aiming to understand why we have become image consumers, those studies tried to recover, based on McDonald's history, economical, social, cultural, and political events that have lead us towards an obsessed image society, in which, "being in the image is the same as existing". Although tragic in its bottom line, that inexistence of form is compensated to us by amusement and happiness images conveyed by the brands. Finally, the research questions the global reach of that promise, starting from a digression on Brazil: how does McDonald's' brand supply us images for a certain identity constitution; and its brand name for a permanence feeling? How is it possible to speak of "identification" with a brand that, seemingly, would not have a

  17. Brief Analysis On Different Organizational Behaviors Between Wal-Mart and McDonald's

    Institute of Scientific and Technical Information of China (English)

    全毅文

    2009-01-01

    @@ At present, increasing companies appeared on the market, and market is just like a big melting furnace. If company can not lay out themselves, company will be eliminated. Many of companies are out of use in the market, but the Walmart and McDonald's talented showing itself in numerous markets and held water in this melting furnace. And how did they achieve their success? General speaking, the organizational structure, culture and perfect management are the most important factors for the two companies. In my report, I will use the Walmart and McDonald's case and compare the two companies' different cultures, structures and managements, and begin to describe the three areas. First chapter will talk about companies' background. Second part will describe the comparison of companies. And third chapter will discuss the development of companies. Now we will walk into the world of Walmart and McDonald, and experience the success of the two enterprises jointly.

  18. Application of the McDonald MRI criteria in multiple sclerosis.

    Science.gov (United States)

    Chan, Ling Ling; Sitoh, Yih Yian; Chong, June; See, Siew Ju; Umapathi, Thirugnanam N; Lim, Shih Hui; Ong, Benjamin

    2007-08-01

    The aim of this study was to assess the sensitivity of McDonald's magnetic resonance imaging (MRI) criteria for the diagnosis of multiple sclerosis (MS) in a group of Asian patients diagnosed with clinically definite MS, based on lesion characterisation on MRI scans. Forty-nine patients from 3 major neurological institutions were classified as having Asian- or Western-type MS based on clinical assessment. Each MRI scan was reviewed by 2 neuroradiologists for the presence and characteristics of brain and spinal lesions. The McDonald's MRI criteria were then applied and its sensitivity evaluated. Nine patients were excluded, leaving 34 females and 6 males who were dominantly Chinese (90%), with a mean age of 36.2 years. The MRI brain and spinal findings were detailed and tabulated. Statistically significant differences (P McDonald's MRI criteria were found between our Asian- and Western-type MS patients. The diagnostic yield of McDonald's MRI criteria increased by 20% when we substituted a cord for a brain lesion, and applied the substitution for enhancing cord lesions as well. The diagnosis is more likely to be made when using McDonald MRI criteria based on brain findings, in a patient who presents clinically with Western-type MS. The provision for substitution of "one brain for a spinal lesion" is helpful in Asian-type MS, where there is preponderance of spinal lesion load. Our findings suggest that minor modifications in the interpretation of McDonald's MRI criteria have significant impact on the diagnosis in patients clinically presenting as Asian-type MS, with potential bearing on their subsequent management.

  19. Crustal deformation and seismic measurements in the region of McDonald Observatory, West Texas. [Texas and Northern Chihuahua, Mexico

    Science.gov (United States)

    Dorman, H. J.

    1981-01-01

    The arrival times of regional and local earthquakes and located earthquakes in the Basin and Range province of Texas and in the adjacent areas of Chihuahua, Mexico from January 1976 to August 1980 at the UT'NASA seismic array are summarized. The August 1931 Texas earthquake is reevaluated and the seismicity and crustal structure of West Texas is examined. A table of seismic stations is included.

  20. McUniversities Revisited: A Comparison of University and McDonald's Casual Employee Experiences in Australia

    Science.gov (United States)

    Nadolny, Andrew; Ryan, Suzanne

    2015-01-01

    The McDonaldization of higher education refers to the transformation of universities from knowledge generators to rational service organizations or "McUniversities". This is reflected in the growing dependence on a casualized academic workforce. The article explores the extent to which the McDonaldization thesis applies to universities…

  1. One ID Card for the Entire Campus.

    Science.gov (United States)

    Ridenour, David P.; Ferguson, Linda M.

    1986-01-01

    The implementation by Indiana State University of a machine-readable photo ID system for their food services prompted an investigation into the available alternatives and requirements for a more efficient all-University ID card system. The new ID system is described. (AUTHOR/MLW)

  2. VLM Tool for IDS Integration

    Directory of Open Access Journals (Sweden)

    Cǎtǎlin NAE

    2010-03-01

    Full Text Available This paper is dedicated to a very specific type of analysis tool (VLM - Vortex Lattice Method to be integrated in a IDS - Integrated Design System, tailored for the usage of small aircraft industry. The major interest is to have the possibility to simulate at very low computational costs a preliminary set of aerodynamic characteristics for basic aerodynamic global characteristics (Lift, Drag, Pitching Moment and aerodynamic derivatives for longitudinal and lateral-directional stability analysis. This work enables fast investigations of the influence of configuration changes in a very efficient computational environment. Using experimental data and/or CFD information for a specific calibration of VLM method, reliability of the analysis may me increased so that a first type (iteration zero aerodynamic evaluation of the preliminary 3D configuration is possible. The output of this tool is basic state aerodynamic and associated stability and control derivatives, as well as a complete set of information on specific loads on major airframe components.The major interest in using and validating this type of methods is coming from the possibility to integrate it as a tool in an IDS system for conceptual design phase, as considered for development for CESAR project (IP, UE FP6.

  3. ID Barrel installed in cryostat

    CERN Multimedia

    Apsimon, R.; Romaniouk, A.

    Wednesday 23rd August was a memorable day for the Inner Detector community as they witnessed the transport and installation of the central part of the inner detector (ID-barrel) into the ATLAS detector. Many members of the collaboration gathered to witness this moment at Point 1. After years of design, construction and commissioning, the outer two detectors (TRT and SCT) of the ID barrel were moved from the SR1 cleanroom to the ATLAS cavern. The barrel was moved across the car park from building 2175 to SX1. Although only a journey of about 100 metres, this required weeks of planning and some degree of luck as far as the weather was concerned. Accelerometers were fitted to the barrel to provide real-time monitoring and no values greater than 0.1 g were recorded, fully satisfying the transport specification for this extremely precise and fragile detector. Muriel, despite her fear of heights, bravely volunteered to keep a close eye on the detector. Swapping cranes to cross the entire parking lot, while Mur...

  4. McJobs and Pieces of Flair: Linking McDonaldization to Alienating Work

    Science.gov (United States)

    Treiber, Linda Ann

    2013-01-01

    This article offers strategies for teaching about rationality, bureaucracy, and social change using George Ritzer's "The McDonaldization of Society" and its ideas about efficiency, predictability, calculability, and control. Student learning is facilitated using a series of strategies: making the familiar strange, explaining…

  5. 'Acting like chameleons’: on the McDonaldization of private security

    NARCIS (Netherlands)

    van Steden, R.; de Waard, J.

    2013-01-01

    Private security is a fragmented industry with tens of thousands of small- and medium-sized suppliers worldwide. However, with the arrival in the market of multinational brands such as Group 4 Securicor and Securitas, we are witnessing a McDonaldization of security commodities. This development

  6. McDonald's restaurants and neighborhood deprivation in Scotland and England.

    Science.gov (United States)

    Cummins, Steven C J; McKay, Laura; MacIntyre, Sally

    2005-11-01

    Features of the local fast food environment have been hypothesized to contribute to the greater prevalence of obesity in deprived neighborhoods. However, few studies have investigated whether fast food outlets are more likely to be found in poorer areas, and those that have are local case studies. In this paper, using national-level data, we examine the association between neighborhood deprivation and the density of McDonald's restaurants in small census areas (neighborhoods) in Scotland and England. Data on population, deprivation, and the location of McDonald's Restaurants were obtained for 38,987 small areas in Scotland and England (6505 "data zones" in Scotland, and 32,482 "super output areas" in England) in January 2005. Measures of McDonald's restaurants per 1000 people for each area were calculated, and areas were divided into quintiles of deprivation. Associations between neighborhood deprivation and outlet density were examined during February 2005, using one-way analysis of variance in Scotland, England, and both countries combined. Statistically significant positive associations were found between neighborhood deprivation and the mean number of McDonald's outlets per 1000 people for Scotland (p<0.001), England (p<0.001), and both countries combined (p<0.001). These associations were broadly linear with greater mean numbers of outlets per 1000 people occurring as deprivation levels increased. Observed associations between presence or absence of fast food outlets and neighborhood deprivation may provide support for environmental explanations for the higher prevalence of obesity in poor neighborhoods.

  7. The Rationalization of Everything? Using Ritzer's McDonaldization Thesis To Teach Weber.

    Science.gov (United States)

    Lippmann, Stephen; Aldrich, Howard

    2003-01-01

    Outlines a plan for helping undergraduate students appreciate Max Weber's theoretical achievements, teaching critical thinking about what constitutes 'the good life' in rationalized societies. Uses the book "The McDonaldization of Society" (George Ritzer) to encourage student interest in Weber's work. Describes field exercises and…

  8. Where Were the Whistleblowers? The Case of Allan McDonald and Roger Boisjoly.

    Science.gov (United States)

    Stewart, Lea P.

    Employees who "blow the whistle" on their company because they believe it is engaged in practices that are illegal, immoral, or harmful to the public, often face grave consequences for their actions, including demotion, harassment, forced resignation, or termination. The case of Allan McDonald and Roger Boisjoly, engineers who blew the…

  9. Beneath the Golden Arches: The McDonald's Corporation [and] Teacher's Guide.

    Science.gov (United States)

    Brufke, Edward F.

    This teacher developed case study which surveys the meteoric rise of the McDonald's Corporation and that of its chief promoter, Ray Kroc, is intended to help secondary students develop an understanding of economics and of the decision-making process. A teacher's guide containing questions for discussion and suggestions for class activities is…

  10. J. Crush and D.A. McDonald. (eds). 2002. Transnationalism and ...

    African Journals Online (AJOL)

    J. Crush and D.A. McDonald. (eds). 2002. Transnationalism and New African Immigration to South Africa. Cape Town. Southern African Migration Project and the Canadian Association of African Studies. IV + 188 pp. ISBN 0-88911-926-0.

  11. Hydrothermal venting on the flanks of Heard and McDonald islands, southern Indian Ocean

    Science.gov (United States)

    Lupton, J. E.; Arculus, R. J.; Coffin, M.; Bradney, A.; Baumberger, T.; Wilkinson, C.

    2017-12-01

    Heard Island and the nearby McDonald Islands are two sites of active volcanism associated with the so-called Kerguelen mantle plume or hot spot. In fact, it has been proposed that the Kerguelen hot spot is currently located beneath Heard Island. During its maiden maximum endurance voyage (IN2016_V01), the recently commissioned Australian R/V Investigator conducted a detailed bathymetric and water column survey of the waters around Heard Island and the McDonald Islands as well as other sites on the Kerguelen Plateau. Some 50 hydrographic profiles were completed using the CTD/rosette system equipped with trace metal sampling and a nephelometer for suspended particle concentrations. In addition to the hydrographic profiles, 244 bubble plumes were detected in the vicinity of the Heard and McDonald Islands using the ship's multibeam system. It is thought that the bubble plumes observed on sea knolls and other seafloor surrounding the McDonald Islands are likely hydrothermal in origin, while plumes northeast of Heard Island may be biogenic methane from cold seeps. At 29 of the hydrographic stations water samples for helium isotope measurements were drawn from the CTD rosette and hermetically sealed into copper tubing for subsequent shorebased mass spectrometer and gas chromatograph analysis. In this paper we report results for 3He/4He ratios and CO2 and CH4 concentrations in water samples collected with the CTD/rosette, and discuss how these results are correlated with suspended particle concentrations and temperature anomalies.

  12. Wij kiezen bij arbeidsomstandigheden voor de grote A : personeelsbeleid is als hamburger voor McDonald's

    NARCIS (Netherlands)

    Bennink, T.; Vergouw, E.

    1998-01-01

    Leuk werken is - volgens Manager Human Resources Lydia van Dongen - een belangrijk aandachtspunt bij de hamburgergigant McDonald's. Daarvoor haalt het bedrijf alles voor uit de kast. Investeren in arbozorg loont. In dit artikel wordt verslag gedaan van een interview met Lydia van Dongen. Hierbij

  13. Knot positioning during McDonald cervical cerclage, does it make a difference? A cohort study.

    Science.gov (United States)

    Atia, Hytham; Ellaithy, Mohamed; Altraigey, Ahmed; Ibrahim, Heba

    2018-05-15

    To study the effect of McDonald cerclage knot position on the different maternal and neonatal outcomes. This historical cohort study included women with singleton pregnancy who had a prophylactic McDonald cervical cerclage between 1 May 2010 and 31 September 2017. Maternal and neonatal outcome parameters were compared between the anterior and posterior knot cerclage procedures. The primary outcome measure was the rate of term birth. 550 Women had a prophylactic McDonald cervical cerclage, 306 with anterior knot (Group A) and 244 with posterior knot (Group B). There were no statistically significant differences regarding gestational age (GA) at delivery (36.3 ± 4.2 versus 35.8 ± 5.3 for groups A and B respectively), term birth rate, post-cerclage cervical length, symptomatic vaginitis, urinary tract infection, difficult cerclage removal and cervical lacerations. Similarly, there were no statistically significant differences as regards the studied neonatal outcomes including take home babies, neonatal intensive care admission, respiratory distress syndrome and neonatal sepsis. Survival analysis on GA at delivery demonstrated no statistically significant difference as regards the proportion of term deliveries in the anterior and posterior knot cerclage groups (log-rank test p-value = .478). Knot positioning during McDonald cervical cerclage, anteriorly or posteriorly, didn't significantly impact the studied maternal and neonatal outcomes.

  14. A Note on McDonald's Generalization of Principal Components Analysis

    Science.gov (United States)

    Shine, Lester C., II

    1972-01-01

    It is shown that McDonald's generalization of Classical Principal Components Analysis to groups of variables maximally channels the totalvariance of the original variables through the groups of variables acting as groups. An equation is obtained for determining the vectors of correlations of the L2 components with the original variables.…

  15. TENCompetence Competence Observatory

    NARCIS (Netherlands)

    Vervenne, Luk

    2010-01-01

    Vervenne, L. (2007) TENCompetence Competence Observatory. Sources available http://tencompetence.cvs.sourceforge.net/viewvc/tencompetence/wp8/org.tencompetence.co/. Available under the three clause BSD license, copyright TENCompetence Foundation.

  16. Long Baseline Observatory (LBO)

    Data.gov (United States)

    Federal Laboratory Consortium — The Long Baseline Observatory (LBO) comprises ten radio telescopes spanning 5,351 miles. It's the world's largest, sharpest, dedicated telescope array. With an eye...

  17. Submarine geology and geomorphology of active Sub-Antarctic volcanoes: Heard and McDonald Islands

    Science.gov (United States)

    Watson, S. J.; Coffin, M. F.; Whittaker, J. M.; Lucieer, V.; Fox, J. M.; Carey, R.; Arculus, R. J.; Bowie, A. R.; Chase, Z.; Robertson, R.; Martin, T.; Cooke, F.

    2016-12-01

    Heard and McDonald Islands (HIMI) are World Heritage listed sub-Antarctic active volcanic islands in the Southern Indian Ocean. Built atop the Kerguelen Plateau by Neogene-Quaternary volcanism, HIMI represent subaerial exposures of the second largest submarine Large Igneous Province globally. Onshore, processes influencing island evolution include glaciers, weathering, volcanism, vertical tectonics and mass-wasting (Duncan et al. 2016). Waters surrounding HIMI are largely uncharted, due to their remote location. Hence, the extent to which these same processes shape the submarine environment around HIMI has not been investigated. In early 2016, we conducted marine geophysical and geologic surveys around HIMI aboard RV Investigator (IN2016_V01). Results show that volcanic and sedimentary features prominently trend east-west, likely a result of erosion by the eastward flowing Antarctic Circumpolar Current and tidal currents. However, spatial patterns of submarine volcanism and sediment distribution differ substantially between the islands. >70 sea knolls surround McDonald Island suggesting substantial submarine volcanism. Geophysical data reveals hard volcanic seafloor around McDonald Island, whereas Heard Island is characterised by sedimentary sequences tens of meters or more thick and iceberg scours - indicative of glacial processes. Differences in submarine geomorphology are likely due to the active glaciation of Heard Island and differing rock types (Heard: alkali basalt, McDonald: phonolite), and dominant products (clastics vs. lava). Variations may also reflect different magmatic plumbing systems beneath the two active volcanoes (Heard produces larger volumes of more focused lava, whilst McDonald extrudes smaller volumes of more evolved lavas from multiple vents across the edifice). Using geophysical data, corroborated with new and existing geologic data, we present the first geomorphic map revealing the processes that shape the submarine environment around HIMI.

  18. The Pierre Auger Observatory

    International Nuclear Information System (INIS)

    Hojvat, C.

    1997-03-01

    The Pierre Auger Observatory is an international collaboration for the detailed study of the highest energy cosmic rays. It will operate at two similar sites, one in the northern hemisphere and one in the southern hemisphere. The Observatory is designed to collect a statistically significant data set of events with energies greater than 10 19 eV and with equal exposures for the northern and southern skies

  19. Observatories and Telescopes of Modern Times

    Science.gov (United States)

    Leverington, David

    2016-11-01

    Preface; Part I. Optical Observatories: 1. Palomar Mountain Observatory; 2. The United States Optical Observatory; 3. From the Next Generation Telescope to Gemini and SOAR; 4. Competing primary mirror designs; 5. Active optics, adaptive optics and other technical innovations; 6. European Northern Observatory and Calar Alto; 7. European Southern Observatory; 8. Mauna Kea Observatory; 9. Australian optical observatories; 10. Mount Hopkins' Whipple Observatory and the MMT; 11. Apache Point Observatory; 12. Carnegie Southern Observatory (Las Campanas); 13. Mount Graham International Optical Observatory; 14. Modern optical interferometers; 15. Solar observatories; Part II. Radio Observatories: 16. Australian radio observatories; 17. Cambridge Mullard Radio Observatory; 18. Jodrell Bank; 19. Early radio observatories away from the Australian-British axis; 20. The American National Radio Astronomy Observatory; 21. Owens Valley and Mauna Kea; 22. Further North and Central American observatories; 23. Further European and Asian radio observatories; 24. ALMA and the South Pole; Name index; Optical observatory and telescope index; Radio observatory and telescope index; General index.

  20. Electron ID in ATLAS Run 2

    CERN Document Server

    Thais, Savannah Jennifer; The ATLAS collaboration

    2018-01-01

    Efficient and accurate electron identification is of critical importance to measuring many physics processes with leptons in the final state, including H->4l, dark vector boson searches, and various SUSY searches. This poster will describe the current status of the Likelihood driven Electron ID, highlighting the recent move from a MC driven ID to a data-driven ID. It will include the most recent identification efficiency and scale-factor measurements. Additionally, it will describe continued improvements for Run 2 electron ID, highlighting improvements in the low pt region and potential Machine Learning improvements.

  1. Tinjauan Desain Website Kemlu.Go.Id

    Directory of Open Access Journals (Sweden)

    Danu Widhyatmoko

    2013-04-01

    Full Text Available Review of kemlu.go.id website design is a research report on Kemlu.go.id website design. Kemlu.go.id website aims to be the information gateway of Ministry of Foreign Affairs, and also as guidelines of foreign politic policies of Republic of Indonesia. The review had been accomplished by using analytical method based on the "Nine Essential Principles for Good Web Design" developed by Collis Ta'eed (2007. At the end of the article, several recommendations in developing kemlu.go.id website are presented to create better appearance.  

  2. Tinjauan Desain Website Kemlu.Go.Id

    OpenAIRE

    Danu Widhyatmoko

    2013-01-01

    Review of kemlu.go.id website design is a research report on Kemlu.go.id website design. Kemlu.go.id website aims to be the information gateway of Ministry of Foreign Affairs, and also as guidelines of foreign politic policies of Republic of Indonesia. The review had been accomplished by using analytical method based on the "Nine Essential Principles for Good Web Design" developed by Collis Ta'eed (2007). At the end of the article, several recommendations in developing kemlu.go.id website are...

  3. Id1 and Id3 expression is associated with increasing grade of prostate cancer: Id3 preferentially regulates CDKN1B

    International Nuclear Information System (INIS)

    Sharma, Pankaj; Patel, Divya; Chaudhary, Jaideep

    2012-01-01

    As transcriptional regulators of basic helix–oop–helix (bHLH) transcription and non-bHLH factors, the inhibitor of differentiation (Id1, Id2, Id3, and Id4) proteins play a critical role in coordinated regulation of cell growth, differentiation, tumorigenesis, and angiogenesis. Id1 regulates prostate cancer (PCa) cell proliferation, apoptosis, and androgen independence, but its clinical significance in PCa remains controversial. Moreover, there is lack of evidence on the expression of Id2 and Id3 in PCa progression. In this study we investigated the expression of Id2 and Id3 and reevaluated the expression of Id1 in PCa. We show that increased Id1 and Id3 protein expression is strongly associated with increasing grade of PCa. At the molecular level, we report that silencing either Id1 or Id3 attenuates cell cycle. Although structurally and mechanistically similar, our results show that both these proteins are noncompensatory at least in PCa progression. Moreover, through gene silencing approaches we show that Id1 and Id3 primarily attenuates CDKN1A (p21) and CDKN1B (p27), respectively. We also demonstrate that silencing Id3 alone significantly attenuates proliferation of PCa cells as compared with Id1. We propose that increased Id1 and Id3 expression attenuates all three cyclin-dependent kinase inhibitors (CDKN2B, -1A, and -1B) resulting in a more aggressive PCa phenotype

  4. [Revision of McDonald's new diagnostic criteria for multiple sclerosis].

    Science.gov (United States)

    Wiendl, H; Kieseier, B C; Gold, R; Hohlfeld, R; Bendszus, M; Hartung, H-P

    2006-10-01

    In 2001, an international panel suggested new diagnostic criteria for multiple sclerosis (MS). These criteria integrate clinical, imaging (MRI), and paraclinical results in order to facilitate diagnosis. Since then, these so-called McDonald criteria have been broadly accepted and widely propagated. In the meantime a number of publications have dealt with the sensitivity and specificity for MS diagnosis and with implementing these new criteria in clinical practice. Based on these empirical values and newer data on MS, an international expert group recently proposed a revision of the criteria. Substantial changes affect (1) MRI criteria for the dissemination of lesions over time, (2) the role of spinal cord lesions in the MRI and (3) diagnosis of primary progressive MS. In this article we present recent experiences with the McDonald and revised criteria.

  5. Globalization Theory: Lessons from the Exportation of McDonaldization and the New Means of Consumption

    Energy Technology Data Exchange (ETDEWEB)

    Ritzer, George (Maryland, Univ Of - College Pa); Malone, Elizabeth L.(BATTELLE (PACIFIC NW LAB)); Ritzer, George

    2001-07-30

    McDonaldization and the exportation of the new means of consumption tend to support the view that in at least some sectors the world is growing more homogeneous than heterogeneous. Against those globalization theorists who tend to focus on the importance of the local and therefore on heterogeneity, the study of McDonaldization and the new means of consumption emphasizes transnational issues and uniformity throughout the world. Fast-food restaurants do adapt to local markets, but the basic procedures of operation and marketing remain the same across a wide range of international settings. This is true even of indigenous versions. The uniformity is exported by transnational corporations, with nation-states less and less able to control or restrict such exports.

  6. Globalization Theory: Lessons from the Exportation of McDonaldization and the New Means of Consumption

    Energy Technology Data Exchange (ETDEWEB)

    Ritzer, George; Malone, Elizabeth L.

    2000-07-31

    McDonaldization and the exportation of the new means of consumption tend to support the view that in at least some sectors the world is growing more homogeneous than heterogeneous. Against those globalization theorists who tend to focus on the importance of the local and therefore on heterogeneity, the study of McDonaldization and the new means of consumption emphasizes transnational issues and uniformity throughout the world. Fast-food restaurants do adapt to local markets, but the basic procedures of operation and marketing remain the same across a wide range of international settings. This is true even of indigenous versions. The uniformity is exported by transnational corporations, with nation-states less and less able to control or restrict such exports.

  7. Most Scottish neurologists do not apply the 2010 McDonald criteria when diagnosing multiple sclerosis.

    Science.gov (United States)

    Lumley, R; Davenport, R; Williams, A

    2015-03-01

    The diagnostic criteria for multiple sclerosis have evolved over time and currently the 2010 McDonald criteria are the most widely accepted. These criteria allow the diagnosis of multiple sclerosis to be made at the clinically isolated syndrome stage provided certain criteria are met on a single magnetic resonance brain scan. Our hypothesis was that neurologists in Scotland did not use these criteria routinely. We sent a SurveyMonkey questionnaire to all Scottish neurologists (consultants and trainees) regarding the diagnosis of multiple sclerosis. Our questionnaire response rate was 65/99 (66%). Most Scottish neurologists were aware of the criteria and 31/58 (53%) felt that they were using these routinely. However, in a clinical vignette designed to test the application of these criteria, only 5/57 (9%) of neurologists appeared to use them. Scottish neurologists' use of the 2010 McDonald criteria for diagnosis of multiple sclerosis varies from practitioners' perception of their use of these criteria.

  8. The world of Ronald McDonald: on the trademark and the mediatic sociality

    OpenAIRE

    Fontenelle, Isleide Arruda

    2002-01-01

    O palhaço Ronald McDonald -- uma das imagens de marca da Corporação McDonald's -- é tomado como paradigma para pensarmos as relações entre mercado, mídia e entretenimento, as quais tem uma ligação direta com o que estamos conceituando como "socialidade midiática". Enquanto uma metáfora ideal de uma propaganda que parece não querer mais fazer sentido, a história do palhaço nos permite desvendar os sentidos contidos em duas das principais práticas do marketing moderno, a propaganda e a publicid...

  9. The McDonald exponentiated gamma distribution and its statistical properties

    OpenAIRE

    Al-Babtain, Abdulhakim A; Merovci, Faton; Elbatal, Ibrahim

    2015-01-01

    Abstract In this paper, we propose a five-parameter lifetime model called the McDonald exponentiated gamma distribution to extend beta exponentiated gamma, Kumaraswamy exponentiated gamma and exponentiated gamma, among several other models. We provide a comprehensive mathematical treatment of this distribution. We derive the moment generating function and the rth moment. We discuss estimation of the parameters by maximum likelihood and provide the information matrix. AMS Subject Classificatio...

  10. Assessing the health impact of transnational corporations: a case study on McDonald?s Australia

    OpenAIRE

    Anaf, Julia; Baum, Frances E.; Fisher, Matt; Harris, Elizabeth; Friel, Sharon

    2017-01-01

    Background The practices of transnational corporations affect population health through production methods, shaping social determinants of health, or influencing the regulatory structures governing their activities. There has been limited research on community exposures to TNC policies and practices. Our pilot research used McDonald?s Australia to test methods for assessing the health impacts of one TNC within Australia. Methods We adapted existing Health Impact Assessment methods to assess M...

  11. Cultural Differences Applied in International Marketing : Cases Of McDonalds and Red Bull

    OpenAIRE

    Abdulkerimova, Assiyat

    2017-01-01

    The main purpose of this thesis is to demonstrate how culture and cultural differences influence on the international marketing. Also, it demonstrates how international companies deal with cross-cultural issues and problems. First, the importance of culture and two models of cultural dimensions like Hofstede and Trompenaars will be analyzed and discussed. Second, the marketing activities of two international corporations- McDonald's and Red Bull will be discussed and analyzed. The research wi...

  12. Management závěrečného turnaje McDonalds cup 2015

    OpenAIRE

    Kafka, Dominik

    2016-01-01

    Title: Management of the McDonald's Cup 2015 final tournament Objectives: The main objective of this thesis is to provide a detailed analysis of the management of the McDonald's Cup 2015 final tournament known as the Festival of Football, to present its strengths, weaknesses, potential opportunities and threats and then, based on previous analyses, to create a list of suggestions and recommendations leading to the elimination of the weaknesses and threats and thus to development, increase of ...

  13. Sponzorský projekt McDonald's Olympic Hopefuls na podporu mladých sportovců.

    OpenAIRE

    Adamec, Richard

    2008-01-01

    This thesis is devoted to the McDonald's Olympic Hopefuls sponsorship project. The first two parts include theoretical essentials for elaboration and the terms concerning marketing. Explanation of terms related to marketing communication and commercial communications is also included in this section. The third part is focused on sponsorship, its types and evaluation of sponsorship projects. The application part describes the history of the McDonald's Olympic Hopefuls project. Evaluation of th...

  14. A proposed HTTP service based IDS

    Directory of Open Access Journals (Sweden)

    Mohamed M. Abd-Eldayem

    2014-03-01

    Full Text Available The tremendous growth of the web-based applications has increased information security vulnerabilities over the Internet. Security administrators use Intrusion-Detection System (IDS to monitor network traffic and host activities to detect attacks against hosts and network resources. In this paper IDS based on Naïve Bayes classifier is analyzed. The main objective is to enhance IDS performance through preparing the training data set allowing to detect malicious connections that exploit the http service. Results of application are demonstrated and discussed. In the training phase of the proposed IDS, at first a feature selection technique based on Naïve Bayes classifier is used, this technique identifies the most important HTTP traffic features that can be used to detect HTTP attacks. In the testing and running phases proposed IDS classifies the network traffic based on the requested service, then based on the selected features Naïve Bayes classifier is used to analyze the HTTP service based traffic and identifies the HTTP normal connections and attacks. The performance of the IDS is measured through experiments using NSL-KDD data set. The results show that the detection rate of the IDS is about 99%, the false-positive rate is about 1%, and the false-negative rate is about 0.25%; therefore, proposed IDS holds the highest detection rate and the lowest false alarm compared with other leading IDS. In addition, the proposed IDS based on Naïve Bayes is used to classify network connections as a normal or attack. And it holds a high detection rate and a low false alarm.

  15. US Naval Observatory Hourly Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hourly observations journal from the National Observatory in Washington DC. The observatory is the first station in the United States to produce hourly observations...

  16. ESO's Two Observatories Merge

    Science.gov (United States)

    2005-02-01

    On February 1, 2005, the European Southern Observatory (ESO) has merged its two observatories, La Silla and Paranal, into one. This move will help Europe's prime organisation for astronomy to better manage its many and diverse projects by deploying available resources more efficiently where and when they are needed. The merged observatory will be known as the La Silla Paranal Observatory. Catherine Cesarsky, ESO's Director General, comments the new development: "The merging, which was planned during the past year with the deep involvement of all the staff, has created unified maintenance and engineering (including software, mechanics, electronics and optics) departments across the two sites, further increasing the already very high efficiency of our telescopes. It is my great pleasure to commend the excellent work of Jorge Melnick, former director of the La Silla Observatory, and of Roberto Gilmozzi, the director of Paranal." ESO's headquarters are located in Garching, in the vicinity of Munich (Bavaria, Germany), and this intergovernmental organisation has established itself as a world-leader in astronomy. Created in 1962, ESO is now supported by eleven member states (Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Portugal, Sweden, Switzerland, and the United Kingdom). It operates major telescopes on two remote sites, all located in Chile: La Silla, about 600 km north of Santiago and at an altitude of 2400m; Paranal, a 2600m high mountain in the Atacama Desert 120 km south of the coastal city of Antofagasta. Most recently, ESO has started the construction of an observatory at Chajnantor, a 5000m high site, also in the Atacama Desert. La Silla, north of the town of La Serena, has been the bastion of the organization's facilities since 1964. It is the site of two of the most productive 4-m class telescopes in the world, the New Technology Telescope (NTT) - the first major telescope equipped with active optics - and the 3.6-m, which hosts HARPS

  17. The impact of a new McDonald's restaurant on eating behaviours and perceptions of local residents: A natural experiment using repeated cross-sectional data.

    Science.gov (United States)

    Thornton, Lukar E; Ball, Kylie; Lamb, Karen E; McCann, Jennifer; Parker, Kate; Crawford, David A

    2016-05-01

    Neighbourhood food environments are posited as an important determinant of eating behaviours; however causality is difficult to establish based on existing studies. Using a natural experiment study design (incorporating repeated cross-sectional data), we tested whether the development of a new McDonald's restaurant increased the frequency of consumption of McDonald's products amongst local residents in the suburbs of Tecoma (site of a new McDonald's restaurant development) and Monbulk (control site) in Victoria, Australia. Across both sites, the reported frequency of McDonald's consumption did not change during the follow-up surveys. In the context explored, the development of a new McDonald's restaurant has not resulted in an increased consumption of McDonald's products. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Expanding the HAWC Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Johanna [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-17

    The High Altitude Water Cherenkov Gamma-Ray Observatory is expanding its current array of 300 water tanks to include 350 outrigger tanks to increase sensitivity to gamma rays above 10 TeV. This involves creating and testing hardware with which to build the new tanks, including photomultiplier tubes, high voltage supply units, and flash analog to digital converters. My responsibilities this summer included preparing, testing and calibrating that equipment.

  19. South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1987-01-01

    Work at the South African Astronomical Observatory (SAAO) in recent years, by both staff and visitors, has made major contributions to the fields of astrophysics and astronomy. During 1986 the SAAO has been involved in studies of the following: galaxies; celestial x-ray sources; magellanic clouds; pulsating variables; galactic structure; binary star phenomena; nebulae and interstellar matter; stellar astrophysics; open clusters; globular clusters, and solar systems

  20. Pengalaman Komunikasi Pelanggan Zalora.co.id (Studi Fenomenologi Pelanggan Zalora.co.id)

    OpenAIRE

    Aji, Widya Andhika; Pradekso, Tandiyo; Ulfa, Nurist Surayya

    2013-01-01

    1PENGALAMAN KOMUNIKASI PELANGGAN ZALORA.CO.ID(Studi Fenomenologi Pelanggan Zalora.co.id)Oleh:Widya Andhika AjiFakultas Ilmu Sosial dan Ilmu PolitikUniversitas Diponegoro SemarangABSTRAKPenelitian ini bertujuan untuk menganalisis pengalaman komunikasi danpemahaman penerimaan konsumen terkait pesan komunikasi pemasaran dalamberbelanja di Zalora.co.id. Dengan menggunakan sampel pada lima informandan metode wawancara, dapat ditarik kesimpulan: Pelanggan Zalora.co.idmemiliki pengalaman komunikasi ...

  1. Id-1 and Id-2 genes and products as markers of epithelial cancer

    Science.gov (United States)

    Desprez, Pierre-Yves [El Cerrito, CA; Campisi, Judith [Berkeley, CA

    2008-09-30

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  2. Astronomical publications of Melbourne Observatory

    Science.gov (United States)

    Andropoulos, Jenny Ioanna

    2014-05-01

    During the second half of the 19th century and the first half of the 20th century, four well-equipped government observatories were maintained in Australia - in Melbourne, Sydney, Adelaide and Perth. These institutions conducted astronomical observations, often in the course of providing a local time service, and they also collected and collated meteorological data. As well, some of these observatories were involved at times in geodetic surveying, geomagnetic recording, gravity measurements, seismology, tide recording and physical standards, so the term "observatory" was being used in a rather broad sense! Despite the international renown that once applied to Williamstown and Melbourne Observatories, relatively little has been written by modern-day scholars about astronomical activities at these observatories. This research is intended to rectify this situation to some extent by gathering, cataloguing and analysing the published astronomical output of the two Observatories to see what contributions they made to science and society. It also compares their contributions with those of Sydney, Adelaide and Perth Observatories. Overall, Williamstown and Melbourne Observatories produced a prodigious amount of material on astronomy in scientific and technical journals, in reports and in newspapers. The other observatories more or less did likewise, so no observatory of those studied markedly outperformed the others in the long term, especially when account is taken of their relative resourcing in staff and equipment.

  3. Sudbury neutrino observatory

    International Nuclear Information System (INIS)

    Ewan, G.T.; Mak, H.B.; Robertson, B.C.

    1985-07-01

    This report discusses the proposal to construct a unique neutrino observatory. The observatory would contain a Cerenkov detector which would be located 2070 m below the earth's surface in an INCO mine at Creighton near Sudbury and would contain 1000 tons of D20 which is an excellent target material. Neutrinos carry detailed information in their spectra on the reactions taking place deep in the interstellar interior and also provide information on supernova explosions. In addition to their role as astrophysical probes a knowledge of the properties of neutrinos is crucial to theories of grand unification. There are three main objectives of the laboratory. The prime objective will be to study B electron neutrinos from the sun by a direct counting method that will measure their energy and direction. The second major objective will be to establish if electron neutrinos change into other neutrino species in transit from the sun to the earth. Finally it is hoped to be able to observe a supernova with the proposed detector. The features of the Sudbury Neutrino Observatory which make it unique are its high sensitivity to electron neutrinos and its ability to detect all other types of neutrinos of energy greater than 2.2 MeV. In section II of this proposal the major physics objectives are discussed in greater detail. A conceptual design for the detector, and measurements and calculations which establish the feasibility of the neutrino experiments are presented in section III. Section IV is comprised of a discussion on the possible location of the laboratory and Section V contains a brief indication of the main areas to be studied in Phase II of the design study

  4. Sudbury neutrino observatory

    International Nuclear Information System (INIS)

    Ewan, G.T.; Evans, H.C.; Lee, H.W.

    1986-10-01

    This report is a supplement to a report (SNO-85-3 (Sudbury Neutrino Observatory)) which contained the results of a feasibility study on the construction of a deep underground neutrino observatory based on a 1000 ton heavy water Cerenkov detector. Neutrinos carry detailed information in their spectra on the reactions taking place deep in the interstellar interior and also provide information on supernova explosions. In addition to their role as astrophysical probes, a knowledge of the properties of neutrinos is crucial to theories of grand unification. The Sudbury Neutrino Observatory is unique in its high sensitivity to electron neutrinos and its ability to detect all other types of neutrinos of energy greater than 2.2 MeV. The results of the July 1985 study indicated that the project is technically feasible in that the proposed detector can measure the direction and energy of electron neutrinos above 7 MeV and the scientific programs will make significant contributions to physics and astrophysics. This present report contains new information obtained since the 1985 feasibility study. The enhanced conversion of neutrinos in the sun and the new physics that could be learned using the heavy water detector are discussed in the physics section. The other sections will discuss progress in the areas of practical importance in achieving the physics objectives such as new techniques to measure, monitor and remove low levels of radioactivity in detector components, ideas on calibration of the detector and so forth. The section entitled Administration contains a membership list of the working groups within the SNO collaboration

  5. The Observatory Health Report

    Directory of Open Access Journals (Sweden)

    Laura Murianni

    2008-06-01

    Full Text Available

    Background: The number of indicators aiming to provide a clear picture of healthcare needs and the quality and efficiency of healthcare systems and services has proliferated in recent years. The activity of the National Observatory on Health Status in the Italian Regions is multidisciplinary, involving around 280 public health care experts, clinicians, demographers, epidemiologists, mathematicians, statisticians and economists who with their different competencies, and scientific interests aim to improve the collective health of individuals and their conditions through the use of “core indicators”. The main outcome of the National Observatory on Health Status in the Italian Regions is the “Osservasalute Report – a report on health status and the quality of healthcare assistance in the Italian Regions”.

    Methods: The Report adopts a comparative analysis, methodology and internationally validated indicators.

    Results: The results of Observatory Report show it is necessary:

    • to improve the monitoring of primary health care services (where the chronic disease could be cared through implementation of clinical path;

     • to improve in certain areas of hospital care such as caesarean deliveries, as well as the average length of stay in the pre-intervention phase, etc.;

    • to try to be more focused on the patients/citizens in our health care services; • to practice more geographical interventions to reduce the North-South divide as well as reduce gender inequity.

    Conclusions: The health status of Italian people is good with positive results and outcomes, but in the meantime some further efforts should be done especially in the South that still has to improve the quality and the organization of health care services. There are huge differences in accuracy and therefore usefulness of the reported data, both between diseases and between

  6. Sudbury neutrino observatory proposal

    International Nuclear Information System (INIS)

    Ewan, G.T.; Evans, H.C.; Lee, H.W.

    1987-10-01

    This report is a proposal by the Sudbury Neutrino Observatory (SNO) collaboration to develop a world class laboratory for neutrino astrophysics. This observatory would contain a large volume heavy water detector which would have the potential to measure both the electron-neutrino flux from the sun and the total solar neutrino flux independent of neutrino type. It will therefore be possible to test models of solar energy generation and, independently, to search for neutrino oscillations with a sensitivity many orders of magnitude greater than that of terrestrial experiments. It will also be possible to search for spectral distortion produced by neutrino oscillations in the dense matter of the sun. Finally the proposed detector would be sensitive to neutrinos from a stellar collapse and would detect neutrinos of all types thus providing detailed information on the masses of muon- and tau-neutrinos. The neutrino detector would contain 1000 tons of D20 and would be located more than 2000 m below ground in the Creighton mine near Sudbury. The operation and performance of the proposed detector are described and the laboratory design is presented. Construction schedules and responsibilities and the planned program of technical studies by the SNO collaboration are outlined. Finally, the total capital cost is estimated to be $35M Canadian and the annual operating cost, after construction, would be $1.8 M Canadian, including the insurance costs of the heavy water

  7. Compliance with McDonald criteria and red flag recognition in a general neurology practice in Ireland.

    LENUS (Irish Health Repository)

    Albertyn, Christine

    2012-02-01

    BACKGROUND: The revised McDonald criteria aim to simplify and speed the diagnosis of multiple sclerosis (MS). An important principle of the criteria holds there should be no better explanation for the clinical presentation. In Miller et al.\\'s consensus statement on the differential diagnosis of MS, red flags are identified that may suggest a non-MS diagnosis. OBJECTIVE: All new patients with a practice diagnosis of MS were assessed for compliance with McDonald criteria. The group of patients not fulfilling criteria was followed up to assess compliance over time. At the end of the follow-up period, red flags were sought in the group of patients who remained McDonald criteria negative. METHODS: Clinical notes and paraclinical tests were examined retrospectively for compliance with McDonald criteria and for the presence of red flags. RESULTS: Sixty-two patients were identified, with two lost to follow-up. Twenty-six (42%) patients fulfilled criteria at diagnosis. After 53 months follow-up, 47 (78%) patients fulfilled criteria. In the 13 (22%) patients who remain McDonald criteria negative, a total of 20 red flags were identified, ranging from one to six per patient. Alternative diagnoses were considered and further investigations performed in 10 patients with no significantly abnormal results. CONCLUSION: Twenty-two percent of patients still do not fulfill McDonald criteria after 53 months. Dissemination in time was not proven in the majority of patients and the lack of follow-up neuroimaging was an important factor in this. Red flags may be useful in identifying alternative diagnoses, but the yield was low in our cohort.

  8. MCDonalds mārketinga komunikācijas analīze : Latvija-Īrija

    OpenAIRE

    Kazakova, Nataļja

    2010-01-01

    Diplomdarba tēma; pētāmās problēmas apraksts: McDonalds pielietoto mārketinga komunikāciju analīze Latvijā un Īrijā; pētījuma veikšanas laikā daudzus uzņēmumus šajās valstīs (un īpaši Latvijā) skar ekonomiskās krīzes sekas, tāpēc ir nepieciešami aplūkot tādu uzņēmumu pieredzi, kas veiksmīgi darbojas starptautiskajā tirgū ilglaicīgi. Atslēgas vārdi: McDonalds, mārketinga komunikācijas, reklāma, preces virzīšana tirgū, e-mārketings, sabiedriskās attiecības, tiešā pārdošana, personiskā apkalp...

  9. The effects of McDonalds, Kentucky Fried Chicken and Pizza Hut meals on recommended diets.

    Science.gov (United States)

    Malouf, N M; Colagiuri, S

    1995-06-01

    The objective was to study the effect of three common takeaway meals on recommended healthy diets. New South Wales Department of Health recommended diets of 5020, 6275, 9205 and 12,540 kilojoules were used. An evening meal from each of these diets was substituted with one of three common fast food chain takeaway meals 1, 2, 3 and 5 times per week. The 3 takeaway meals were from McDonalds, Pizza Hut and Kentucky Fried Chicken. The effects of each of these meals on average daily kilojoule, fibre, fat, P/S ratio, protein and carbohydrate intakes were assessed. The takeaway meals were high in fat and kilojoules and low in fibre and therefore contravened the Dietary Guidelines for Australians. Addition of these meals increased average kilojoule consumption and the percentage energy contribution of fat and decreased the P/S ratio and fibre intake. The magnitude of these deleterious effects was directly proportional to the number of times the meals were included each week and inversely proportional to the energy content of the diet. The adverse effects were greatest with the McDonalds and Kentucky Fried Chicken meals. Takeaway meals may be convenient but the meals which were tested were too high in fat and kilojoules and too low in fibre to be a regular part of a balanced diet. Even one takeaway meal per week adversely affects the lower kilojoule recommended healthy diets.

  10. Perennial Environment Observatory

    International Nuclear Information System (INIS)

    Plas, Frederic

    2014-07-01

    The Perennial Environment Observatory [Observatoire Perenne de l'Environnement - OPE] is a unique approach and infrastructure developed and implemented by ANDRA, the French National Radioactive Waste Management Agency, as part of its overall project of deep geological disposal for radioactive waste. Its current mission is to assess the initial state of the rural (forest, pasture, open-field and aquatic) environment, prior to repository construction. This will be followed in 2017 (pending construction authorizations) and for a period exceeding a century, by monitoring of any impact the repository may have on the environment. In addition to serving its own industrial purpose of environmental monitoring, ANDRA also opens the OPE approach, infrastructure and acquired knowledge (database...) to the scientific community to support further research on long term evolution of the environment subjected to natural and anthropogenic stresses, and to contribute to a better understanding of the interaction between the various compartments of the environment

  11. Vibrational measurements in 3-ID-B

    International Nuclear Information System (INIS)

    Sutter, J.; Alp, E.; Barraza, J.; Shu, D.

    1998-04-01

    The authors have undertaken a series of vibrational measurements in hutch 3-ID-B. Their motivation was to compare two different methods of mounting an interferometer for effectiveness in vibrational isolation and stability. In addition they were able to compare the stability of the optical table with and without its eight large bolts inserted

  12. Independence Day 2004 (ID04) / Raul Hindov

    Index Scriptorium Estoniae

    Hindov, Raul

    2004-01-01

    Ülevaade 20.-22. veebruarini 2004 toimunud kaugluurepatrullide rännaku ja sõdurioskuste kompleksõppusest ID04 (Independence Day 2004 - Iseseisvuspäev 2004), millel osales 25 patrullvõistlusteks valmistuvat meest ja naist

  13. Sudbury Neutrino Observatory

    International Nuclear Information System (INIS)

    Beier, E.W.

    1992-03-01

    This document is a technical progress report on work performed at the University of Pennsylvania during the current year on the Sudbury Neutrino Observatory project. The motivation for the experiment is the measurement of neutrinos emitted by the sun. The Sudbury Neutrino Observatory (SNO) is a second generation dedicated solar neutrino experiment which will extend the results of our work with the Kamiokande II detector by measuring three reactions of neutrinos rather than the single reaction measured by the Kamiokande experiment. The collaborative project includes physicists from Canada, the United Kingdom, and the United States. Full funding for the construction of this facility was obtained in January 1990, and its construction is estimated to take five years. The motivation for the SNO experiment is to study the fundamental properties of neutrinos, in particular the mass and mixing parameters, which remain undetermined after decades of experiments in neutrino physics utilizing accelerators and reactors as sources of neutrinos. To continue the study of neutrino properties it is necessary to use the sun as a neutrino source. The long distance to the sun makes the search for neutrino mass sensitive to much smaller mass than can be studied with terrestrial sources. Furthermore, the matter density in the sun is sufficiently large to enhance the effects of small mixing between electron neutrinos and mu or tau neutrinos. This experiment, when combined with the results of the radiochemical 37 Cl and 71 Ga experiments and the Kamiokande II experiment, should extend our knowledge of these fundamental particles, and as a byproduct, improve our understanding of energy generation in the sun

  14. McDonald's zjednodušuje mezinárodní ekonomická srovnání

    Czech Academy of Sciences Publication Activity Database

    Jurajda, Štěpán; Dušek, Libor

    -, č. 4 (2007), s. 12-13 ISSN 1210-9525 Institutional research plan: CEZ:AV0Z70850503 Keywords : wages * international comparison Subject RIV: AH - Economics http://abicko.avcr.cz/cs/2007/4/06/ mcdonalds -zjednodusuje-mezinarodni-ekonomicka-srovnani.html

  15. THE PROCESS OF WASTE MANAGEMENT IN POST-CONSUMER PACKAGING: CASE STUDY MCDONALD'S

    Directory of Open Access Journals (Sweden)

    Robson dos Santos

    2013-09-01

    Full Text Available This research considers the increasing concern of society in general environmental issues, shows the importance of an Environmental Management System to improve the image of a company towards society in which it is embedded. Shows that proper waste management can result in financial and environmental benefits for companies that practice. To address the practical issues of the theme, was chosen the company McDonald's, as a service company fast food, that have a quantity of waste, and creates conditions for application of the techniques of environmental management in this sector. Thus, this article aims to demonstrate through case study and descriptive research, the commitment that this large network of fast-food has with the preservation of the environment through its waste management and investments in economic, social and environmental the country.

  16. Health observatories in iran.

    Science.gov (United States)

    Rashidian, A; Damari, B; Larijani, B; Vosoogh Moghadda, A; Alikhani, S; Shadpour, K; Khosravi, A

    2013-01-01

    The Islamic Republic of Iran, in her 20 year vision by the year 2025, is a developed country with the first economic, scientific and technological status in the region, with revolutionary and Islamic identity, inspiring Islamic world, as well as effective and constructive interaction in international relations. Enjoying health, welfare, food security, social security, equal opportunities, fair income distribution, strong family structure; to be away from poverty, corruption, and discrimination; and benefiting desirable living environment are also considered out of characteristics of Iranian society in that year. Strategic leadership towards perceived vision in each setting requires restrictive, complete and timely information. According to constitution of National Institute for Health Researches, law of the Fifth Development Plan of the country and characteristics of health policy making, necessity of designing a Health Observatory System (HOS) was felt. Some Principles for designing such system were formulated by taking following steps: reviewing experience in other countries, having local history of the HOS in mind, superior documents, analysis of current production and management of health information, taking the possibilities to run a HOS into account. Based on these principles, the protocol of HOS was outlined in 3 different stages of opinion poll of informed experts responsible for production on management of information, by using questionnaires and Focus Group Discussions. The protocol includes executive regulations, the list of health indicators, vocabulary and a calendar for periodic studies of the community health situation.

  17. The Sudbury Neutrino Observatory

    International Nuclear Information System (INIS)

    Norman, E.B.; Chan, Y.D.; Garcia, A.; Lesko, K.T.; Smith, A.R.; Stokstad, R.G.; Zlimen, I.; Evans, H.C.; Ewan, G.T.; Hallin, A.; Lee, H.W.; Leslie, J.R.; MacArthur, J.D.; Mak, H.B.; McDonald, A.B.; McLatchie, W.; Robertson, B.C.; Skensved, P.; Sur, B.; Jagam, P.; Law, J.; Ollerhead, R.W.; Simpson, J.J.; Wang, J.X.; Tanner, N.W.; Jelley, N.A.; Barton, J.C.; Doucas, G.; Hooper, E.W.; Knox, A.B.; Moorhead, M.E.; Omori, M.; Trent, P.T.; Wark, D.L.

    1992-11-01

    Two experiments now in progress have reported measurements of the flux of high energy neutrinos from the Sun. Since about 1970, Davis and his co-workers have been using a 37 Cl-based detector to measure the 7 Be and 8 B solar neutrino flux and have found it to be at least a factor of three lower than that predicted by the Standard Solar Model (SSM). The Kamiokande collaborations has been taking data since 1986 using a large light-water Cerenkov detector and have confirmed that the flux is about two times lower than predicted. Recent results from the SAGE and GALLEX gallium-based detectors show that there is also a deficit of the low energy pp solar neutrinos. These discrepancies between experiment and theory could arise because of inadequacies in the theoretical models of solar energy generation or because of previously unobserved properties of neutrinos. The Sudbury Neutrino Observatory (SNO) will provide the information necessary to decide which of these solutions to the ''solar neutrino problem'' is correct

  18. Twenty Years of Precise Radial Velocities at Keck and Lick Observatories

    Science.gov (United States)

    Wright, J. T.

    2015-10-01

    The precise radial velocity survey at Keck Observatory began over 20 years ago. Its survey of thousands of stars now has the time baseline to be sensitive to planets with decade-long orbits, including Jupiter analogs. I present several newly-finished orbital solutions for long-period giant planets. Although hot Jupiters are generally ``lonely'' (i.e. they are not part of multiplanet systems), those that are not appear to often have giant companions at 5 AU or beyond. I present two of the highest period-ratios among planets in a two-planet system, and some of the longest orbital periods ever measured for exoplanets. In many cases, combining Keck radial velocities from those from other long-term surveys at Lick Observatory, McDonald Observatory, HARPS, and, of course, OHP spectrographs, produces superior orbital fits, constraining both period and eccentricity better than could be possible with any single set alone. Stellar magnetic activity cycles can masquerade as long-period planets. In most cases this effect is very small, but a loud minority of stars, including, apparently, HD 154345, show very strong RV-activity correlations.

  19. The Sudbury neutrino observatory

    International Nuclear Information System (INIS)

    McLatchie, W.; Earle, E.D.

    1987-08-01

    This report initially discusses the Homestake Mine Experiment, South Dakota, U.S.A. which has been detecting neutrinos in 38 x 10 litre vats of cleaning fluid containing chlorine since the 1960's. The interation between neutrinos and chlorine produces argon so the number of neutrinos over time can be calculated. However, the number of neutrinos which have been detected represent only one third to one quarter of the expected number i.e. 11 per month rather than 48. It is postulated that the electron-neutrinos originating in the solar core could change into muon- or tau-neutrinos during passage through the high electron densities of the sun. The 'low' results at Homestake could thus be explained by the fact that the experiment is only sensitive to electron-neutrinos. The construction of a heavy water detector is therefore proposed as it would be able to determine the energy of the neutrinos, their time of arrival at the detector and their direction. It is proposed to build the detector at Creighton mine near Sudbury at a depth of 6800 feet below ground level thus shielding the detector from cosmic rays which would completely obscure the neutrino signals from the detector. The report then discusses the facility itself, the budget estimate and the social and economic impact on the surrounding area. At the time of publication the proposal for the Sudbury Neutrino Observatory was due to be submitted for peer review by Oct. 1, 1987 and then to various granting bodies charged with the funding of scientific research in Canada, the U.S.A. and Britain

  20. Beam transport radiation shielding for branch lines 2-ID-B and 2-ID-C

    International Nuclear Information System (INIS)

    Feng, Y.P.; Lai, B.; McNulty, I.; Dejus, R.J.; Randall, K.J.; Yun, W.

    1995-01-01

    The x-ray radiation shielding requirements beyond the first optics enclosure have been considered for the beam transport of the 2-ID-B and 2-ID-C branch lines of Sector 2 (SRI-CAT) of the APS. The first three optical components (mirrors) of the 2-ID-B branch are contained within the shielded first optics enclosure. Calculations indicate that scattering of the primary synchrotron beam by beamline components outside the enclosure, such as apertures and monochromators, or by gas particles in case of vacuum failure is within safe limits for this branch. A standard 2.5-inch-diameter stainless steel pipe with 1/16-inch-thick walls provides adequate shielding to reduce the radiation dose equivalent rate to human tissue to below the maximum permissible limit of 0.25 mrem/hr. The 2-ID-C branch requires, between the first optics enclosure where only two mirrors are used and the housing for the third mirror, additional lead shielding (0.75 mm) and a minimum approach distance of 2.6 cm. A direct beam stop consisting of at least 4.5 mm of lead is also required immediately downstream of the third mirror for 2-ID-C. Finally, to stop the direct beam from escaping the experimental station, a beam stop consisting of at least 4-mm or 2.5-mm steel is required for the 2-ID-B or 2-ID-C branches, respectively. This final requirement can be met by the vacuum chambers used to house the experiments for both branch lines

  1. An astronomical observatory for Peru

    Science.gov (United States)

    del Mar, Juan Quintanilla; Sicardy, Bruno; Giraldo, Víctor Ayma; Callo, Víctor Raúl Aguilar

    2011-06-01

    Peru and France are to conclude an agreement to provide Peru with an astronomical observatory equipped with a 60-cm diameter telescope. The principal aims of this project are to establish and develop research and teaching in astronomy. Since 2004, a team of researchers from Paris Observatory has been working with the University of Cusco (UNSAAC) on the educational, technical and financial aspects of implementing this venture. During an international astronomy conference in Cusco in July 2009, the foundation stone of the future Peruvian Observatory was laid at the top of Pachatusan Mountain. UNSAAC, represented by its Rector, together with the town of Oropesa and the Cusco regional authority, undertook to make the sum of 300,000€ available to the project. An agreement between Paris Observatory and UNSAAC now enables Peruvian students to study astronomy through online teaching.

  2. Astronomical databases of Nikolaev Observatory

    Science.gov (United States)

    Protsyuk, Y.; Mazhaev, A.

    2008-07-01

    Several astronomical databases were created at Nikolaev Observatory during the last years. The databases are built by using MySQL search engine and PHP scripts. They are available on NAO web-site http://www.mao.nikolaev.ua.

  3. Geomagnetic Observatory Database February 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA National Centers for Environmental Information (formerly National Geophysical Data Center) maintains an active database of worldwide geomagnetic observatory...

  4. The South African astronomical observatory

    International Nuclear Information System (INIS)

    Feast, M.

    1985-01-01

    A few examples of the activities of the South African Astronomical Observatory are discussed. This includes the studying of stellar evolution, dust around stars, the determination of distances to galaxies and collaboration with space experiments

  5. The South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1988-01-01

    The geographical position, climate and equipment at the South African Astronomical Observatory (SAAO), together with the enthusiasm and efforts of SAAO scientific and technical staff and of visiting scientists, have enabled the Observatory to make a major contribution to the fields of astrophysics and cosmology. During 1987 the SAAO has been involved in studies of the following: supernovae; galaxies, including Seyfert galaxies; celestial x-ray sources; magellanic clouds; pulsating variables; galatic structure; binary star phenomena; nebulae; interstellar matter and stellar astrophysics

  6. Idékatalog Appetit på maden

    DEFF Research Database (Denmark)

    Jensen, Tenna; Jespersen, Astrid Pernille; Grønnow, Liv Cæcilie

    2015-01-01

    Idékataloget er en selvstændig publikation hørende til projekt Appetit på maden. Idékataloget er udviklet til brug i Københavns Kommune.......Idékataloget er en selvstændig publikation hørende til projekt Appetit på maden. Idékataloget er udviklet til brug i Københavns Kommune....

  7. Group-ID based RFID Mutual Authentication

    Directory of Open Access Journals (Sweden)

    LEE, Y.

    2013-11-01

    Full Text Available For passive type RFID tags, EPCglobal Class 1 Generation-2 Revision is used widely as a de facto standard. As it was designed for low cost, it is quite vulnerable to security issues, such as privacy concerns. This paper presents a new RFID mutual authentication protocol, which is designed to be configured on EPC Gen2 platform and to meet various security requirements while providing efficiency using PRNG (Pseudo Random Number Generator. Group-ID is used to minimize the authentication time. Security analysis of the proposed protocol is discussed.

  8. The Carl Sagan solar and stellar observatories as remote observatories

    Science.gov (United States)

    Saucedo-Morales, J.; Loera-Gonzalez, P.

    In this work we summarize recent efforts made by the University of Sonora, with the goal of expanding the capability for remote operation of the Carl Sagan Solar and Stellar Observatories, as well as the first steps that have been taken in order to achieve autonomous robotic operation in the near future. The solar observatory was established in 2007 on the university campus by our late colleague A. Sánchez-Ibarra. It consists of four solar telescopes mounted on a single equatorial mount. On the other hand, the stellar observatory, which saw the first light on 16 February 2010, is located 21 km away from Hermosillo, Sonora at the site of the School of Agriculture of the University of Sonora. Both observatories can now be remotely controlled, and to some extent are able to operate autonomously. In this paper we discuss how this has been accomplished in terms of the use of software as well as the instruments under control. We also briefly discuss the main scientific and educational objectives, the future plans to improve the control software and to construct an autonomous observatory on a mountain site, as well as the opportunities for collaborations.

  9. The Observatory as Laboratory: Spectral Analysis at Mount Wilson Observatory

    Science.gov (United States)

    Brashear, Ronald

    2018-01-01

    This paper will discuss the seminal changes in astronomical research practices made at the Mount Wilson Observatory in the early twentieth century by George Ellery Hale and his staff. Hale’s desire to set the agenda for solar and stellar astronomical research is often described in terms of his new telescopes, primarily the solar tower observatories and the 60- and 100-inch telescopes on Mount Wilson. This paper will focus more on the ancillary but no less critical parts of Hale’s research mission: the establishment of associated “physical” laboratories as part of the observatory complex where observational spectral data could be quickly compared with spectra obtained using specialized laboratory equipment. Hale built a spectroscopic laboratory on the mountain and a more elaborate physical laboratory in Pasadena and staffed it with highly trained physicists, not classically trained astronomers. The success of Hale’s vision for an astronomical observatory quickly made the Carnegie Institution’s Mount Wilson Observatory one of the most important astrophysical research centers in the world.

  10. Taurus Hill Observatory Scientific Observations for Pulkova Observatory during the 2016-2017 Season

    Science.gov (United States)

    Hentunen, V.-P.; Haukka, H.; Heikkinen, E.; Salmi, T.; Juutilainen, J.

    2017-09-01

    Taurus Hill Observatory (THO), observatory code A95, is an amateur observatory located in Varkaus, Finland. The observatory is maintained by the local astronomical association Warkauden Kassiopeia. THO research team has observed and measured various stellar objects and phenomena. Observatory has mainly focused on exoplanet light curve measurements, observing the gamma rays burst, supernova discoveries and monitoring. We also do long term monitoring projects.

  11. Automatic spent fuel ID number reader (I)

    International Nuclear Information System (INIS)

    Tanabe, S.; Kawamoto, H.; Fujimaki, K.; Kobe, A.

    1991-01-01

    An effective and efficient technique has been developed for facilitating identification works of LWR spent fuel stored in large scale spent fuel storage pools of such as processing plants. Experience shows that there are often difficulties in the implementation of operator's nuclear material accountancy and control works as well as safeguards inspections conducted on spent fuel assemblies stored in deep water pool. This paper reports that the technique is realized as an automatic spent fuel ID number reader system installed on fuel handling machine. The ID number reader system consists of an optical sub-system and an image processing sub-system. Thousands of spent fuel assemblies stored in under water open racks in each storage pool could be identified within relatively short time (e.g. within several hours) by using this combination. Various performance tests were carried out on image processing sub-system in 1990 using TV images obtained from different types of spent fuel assemblies stored in various storage pools of PWR and BWR power stations

  12. GEOSCOPE Observatory Recent Developments

    Science.gov (United States)

    Leroy, N.; Pardo, C.; Bonaime, S.; Stutzmann, E.; Maggi, A.

    2010-12-01

    The GEOSCOPE observatory consists of a global seismic network and a data center. The 31 GEOSCOPE stations are installed in 19 countries, across all continents and on islands throughout the oceans. They are equipped with three component very broadband seismometers (STS1 or STS2) and 24 or 26 bit digitizers, as required by the Federation of Seismic Digital Network (FDSN). In most stations, a pressure gauge and a thermometer are also installed. Currently, 23 stations send data in real or near real time to GEOSCOPE Data Center and tsunami warning centers. In 2009, two stations (SSB and PPTF) have been equipped with warpless base plates. Analysis of one year of data shows that the new installation decreases long period noise (20s to 1000s) by 10 db on horizontal components. SSB is now rated in the top ten long period stations for horizontal components according to the LDEO criteria. In 2010, Stations COYC, PEL and RER have been upgraded with Q330HR, Metrozet electronics and warpless base plates. They have been calibrated with the calibration table CT-EW1 and the software jSeisCal and Calex-EW. Aluminum jars are now installed instead of glass bells. A vacuum of 100 mbars is applied in the jars which improves thermal insulation of the seismometers and reduces moisture and long-term corrosion in the sensor. A new station RODM has just been installed in Rodrigues Island in Mauritius with standard Geoscope STS2 setup: STS2 seismometer on a granite base plate and covered by cooking pot and thermal insulation, it is connected to Q330HR digitizer, active lightning protection, Seiscomp PC and real-time internet connection. Continuous data of all stations are collected in real time or with a delay by the GEOSCOPE Data Center in Paris where they are validated, archived and made available to the international scientific community. Data are freely available to users by different interfaces according data types (see : http://geoscope.ipgp.fr) - Continuous data in real time coming

  13. Analisis Faktor-faktor Preferensi Pelanggan Dan Pengaruhnya Terhadap Keputusan Pembelian (Studi Terhadap Pelanggan Mcdonald's Di Indonesia Dan Malaysia)

    OpenAIRE

    Erinda, Aisyah; Kumadji, Srikandi; Sunarti,

    2016-01-01

    The purpose of this study to determine factor of consumer preference for McDonalds and the effect of Purchasing Decision. There are 21 variable factors of consumer preferences used in this study as well as its influence on the purchase decision. The type of this research is explanatory research with quantitative approach. Location of the study was conducted in Indonesia and Malaysia. The sampling technique of this study used formula from Machin and Campbell (1987:89). The sample in this study...

  14. A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis.

    LENUS (Irish Health Repository)

    Kelly, S B

    2013-07-01

    The diagnostic criteria for primary-progressive multiple sclerosis (PPMS) have undergone revision over the last 20 years. Cerebrospinal fluid oligoclonal bands (CSFOBs) have received less emphasis in recent revisions of the McDonald criteria. The aim of this study was to examine the sensitivity of the diagnostic criteria for PPMS with particular reference to spinal cord criteria and examine the utility of CSFOBs in a cohort of PPMS patients.

  15. Griffith Observatory: Hollywood's Celestial Theater

    Science.gov (United States)

    Margolis, Emily A.; Dr. Stuart W. Leslie

    2018-01-01

    The Griffith Observatory, perched atop the Hollywood Hills, is perhaps the most recognizable observatory in the world. Since opening in 1935, this Los Angeles icon has brought millions of visitors closer to the heavens. Through an analysis of planning documentation, internal newsletters, media coverage, programming and exhibition design, I demonstrate how the Observatory’s Southern California location shaped its form and function. The astronomical community at nearby Mt. Wilson Observatory and Caltech informed the selection of instrumentation and programming, especially for presentations with the Observatory’s Zeiss Planetarium, the second installed in the United States. Meanwhile the Observatory staff called upon some of Hollywood’s best artists, model makers, and scriptwriters to translate the latest astronomical discoveries into spectacular audiovisual experiences, which were enhanced with Space Age technological displays on loan from Southern California’s aerospace companies. The influences of these three communities- professional astronomy, entertainment, and aerospace- persist today and continue to make Griffith Observatory one of the premiere sites of public astronomy in the country.

  16. Mr. Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, United Kingdom

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photos 01,02: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (third from left, front) in front of the ATLAS End-Cap Toroid vacuum vessel in the ATLAS assembly hall with, from left to right, Fred Wickens, Chris Jones, Peter Fletcher, Ray Browne, Neil Geddes, Jim Fleming, Anne Trefethen, Jim Wilson, Edwin Towndrow, Sharon Bonfield, Guy Rickett, Ken Smith, Peter Jenni. Photo 03: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fifth from left) visiting ATLAS assembly hall with, from left to right, Jim Wilson, Peter Jenni, Ken Smith, Edwin Towndrow, Ray Brown, Chris Jones, Neil Geddes, Sharon Bonfield, Anne Trefethen, Jim Fleming, Fred Wickens. Photo 04: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fourth from right) in front of the ATLAS Barrel Toroid coil casing in the ATLAS assembly hall with, from left to right, Peter Jenni, Jim Wilson, Guy Rickett, Anne Trefethen, ...

  17. McDonaldization or commercial re-stratification: corporatization and the multimodal organisation of English doctors.

    Science.gov (United States)

    Waring, Justin; Bishop, Simon

    2013-04-01

    This paper investigates transitions in the social organisation of medicine found in the extended opportunities for private corporations to own, manage and deliver public healthcare services in the English National Health Service. It follows recent calls to explain the reconstruction of medical work without reducing analysis to either the structures of organisational control or the strategic resistance of doctors. Accordingly, the paper considers how doctors interact, mediate and co-create new organisational environments. Central to our analysis are the variable sources of power that influence whether doctors acquiesce, resist or re-create change. Drawing on ethnographic research carried out between 2006 and 2010 in two Independent Sector Treatment Centres - private providers of public healthcare - the paper shows how doctors' responses to bureaucratic and commercial structures reflect their own structured forms of power, which have variable value within this new commercial environment. These include clinical experience and specialist knowledge, but also social and economic influence. Building on established sociological debates, these divergent sources of power explain how for some doctors the expansion of private healthcare might involve more extreme forms of McDonaldization, while for others it might involve opportunities for Commercial Re-stratification. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. The McDonaldization of childhood: children's mental health in neo-liberal market cultures.

    Science.gov (United States)

    Timimi, Sami

    2010-11-01

    As the failings of neo-liberalism have recently been revealed through the collapse of much of the banking and financial services sector, it seems an opportune time to think about the impact this economic, political, and social value system has had on the well-being of children. After analyzing how our beliefs and practices around children and families are shaped by a variety of economic, political, and cultural pressures, I discuss how policies that promote a particular form of aggressive capitalism lead to a narcissistic value system that permeates social institutions, including those that deal with children. Not only does this impact children's emotional well-being, but it also shapes the way we conceptualize children and their problems. These dynamics facilitate the rapid growth of child psychiatric diagnoses and the tendency to deal with aberrant behavior or emotions in children through technical--particularly pharmaceutical--interventions, a phenomenon I refer to as the 'McDonaldization' of children's mental health. The present article seeks to challenge many of the unhelpful cultural assumptions regarding childhood embedded within the narrow biomedical frame that neo-liberalism has encouraged.

  19. Regulation of trans fats: the gap, the Polder, and McDonald's French fries.

    Science.gov (United States)

    Katan, Martijn B

    2006-05-01

    Lowering the intake of trans fatty acids (TFA) probably reduces the incidence of coronary heart disease. Estimates of the reduction vary from 4% based on changes in plasma LDL and HDL concentrations alone, to > 20% based on epidemiological associations when TFA intake is lowered by 2% of energy (5 g/day). Even the lowest estimate represents enough cases to justify measures to reduce TFA intake. In The Netherlands, a major reduction in TFA content of retail foods has been achieved in the 1990s through efforts of industry; government intervention has been minimal. Societal pressure is now helping to reduce the TFA content of fast foods. McDonald's French fries in The Netherlands now have less than 4% trans and 24% saturates, as opposed to 21% trans and 21% saturates in the USA. This illustrates the feasibility of reducing TFA in fast foods without increasing saturates. As a result of these developments, dairy and meat have become the major remaining source of TFA in Europe. The question whether these ruminant TFA have the same effect on coronary heart disease risk as industrial TFA has not been settled.

  20. To ID or Not to ID? Changes in Classification Rates of Intellectual Disability Using "DSM-5"

    Science.gov (United States)

    Papazoglou, Aimilia; Jacobson, Lisa A.; McCabe, Marie; Kaufmann, Walter; Zabel, T. Andrew

    2014-01-01

    The "Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition" ("DSM-5") diagnostic criteria for intellectual disability (ID) include a change to the definition of adaptive impairment. New criteria require impairment in one adaptive domain rather than two or more skill areas. The authors examined the diagnostic…

  1. Visits to La Plata Observatory

    Science.gov (United States)

    Feinstein, A.

    1985-03-01

    La Plata Observatory will welcome visitors to ESO-La Silla that are willing to make a stop at Buenos Aires on their trip to Chile or on their way back. There is a nice guesthouse at the Observatory that can be used, for a couple of days or so, by astronomers interested in visiting the Observatory and delivering talks on their research work to the Argentine colleagues. No payments can, however, be made at present. La Plata is at 60 km from Buenos Aires. In the same area lie the Instituto de Astronomia y Fisica dei Espacio (IAFE), in Buenos Aires proper, and the Instituto Argentino de Radioastronomia (IAR). about 40 km from Buenos Aires on the way to La Plata. Those interested should contacl: Sr Decano Prof. Cesar A. Mondinalli, or Dr Alejandro Feinstein, Observatorio Astron6mico, Paseo dei Bosque, 1900 La Plata, Argentina. Telex: 31216 CESLA AR.

  2. Astronomical Research Using Virtual Observatories

    Directory of Open Access Journals (Sweden)

    M Tanaka

    2010-01-01

    Full Text Available The Virtual Observatory (VO for Astronomy is a framework that empowers astronomical research by providing standard methods to find, access, and utilize astronomical data archives distributed around the world. VO projects in the world have been strenuously developing VO software tools and/or portal systems. Interoperability among VO projects has been achieved with the VO standard protocols defined by the International Virtual Observatory Alliance (IVOA. As a result, VO technologies are now used in obtaining astronomical research results from a huge amount of data. We describe typical examples of astronomical research enabled by the astronomical VO, and describe how the VO technologies are used in the research.

  3. The South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1989-01-01

    The research work discussed in this report covers a wide range, from work on the nearest stars to studies of the distant quasars, and the astronomers who have carried out this work come from universities and observatories spread around the world as well as from South African universities and from the South African Astronomical Observatory (SAAO) staff itself. A characteristic of much of this work has been its collaborative character. SAAO studies in 1989 included: supernovae 1987A; galaxies; ground-based observations of celestial x-ray sources; the Magellanic Clouds; pulsating variables; galactic structure; binary star phenomena; the provision of photometric standards; nebulous matter; stellar astrophysics, and astrometry

  4. McDonald versus Shirodkar cervical cerclage for the prevention of preterm birth: impact of body mass index.

    Science.gov (United States)

    Figueroa, Reinaldo; Crowell, Rebecca; Martinez, Alvin; Morgan, Marielle; Wakefield, Dorothy

    2018-04-30

    To compare obstetrical outcomes on women undergoing a McDonald or Shirodkar cerclage and to estimate the impact of maternal body mass index (BMI) on these outcomes. We conducted a retrospective review of the medical records of all women with singleton pregnancies who underwent placement of a McDonald or Shirodkar cerclage at St. Francis Hospital from January 2008 to October 2013. The subjects were categorized based on BMI groups (normal: less than 25 kg/m 2 , overweight: 25-29 kg/m 2 , obese: 30 kg/m 2 or more). The primary outcome was gestational age at delivery. Statistical analyses included chi-square, Student's t-test, and multivariable regression analysis. Of 95 women, 47 (49.5%) received a Shirodkar, and 48 (50.5%) a McDonald cerclage. 16 women (16.8%) were categorized as normal weight, 35 (36.8%) as overweight, and 44 (46.3%) as obese. Gestational age at delivery differed significantly by group, decreasing with each categorical increase in BMI (normal: 39.0 ± 0.3 weeks; overweight: 36.6 ± 0.7 weeks; obese: 33.0 ± 1.1 weeks; p McDonald cerclage (36.7 ± 0.6 weeks versus 33.9 ± 1.0 weeks; p = .02). However, analysis showed a significant interaction between weight status and gestational age at delivery. Obese women had significantly longer pregnancies when they received a Shirodkar cerclage versus a McDonald cerclage (32.6 ± 1.0 weeks versus 28.8 ± 0.9 weeks; p McDonald: 32.9 ± 0.9 weeks; p = .63). Compared to obese women receiving a McDonald cerclage, obese women receiving a Shirodkar cerclage had significantly longer pregnancies. No significant differences in pregnancy duration were found in normal/overweight women regardless of cerclage technique. Pregnancy duration in obese women receiving a Shirodkar cerclage was similar to the pregnancy duration of normal/overweight women.

  5. Improvements in geomagnetic observatory data quality

    DEFF Research Database (Denmark)

    Reda, Jan; Fouassier, Danielle; Isac, Anca

    2011-01-01

    between observatories and the establishment of observatory networks has harmonized standards and practices across the world; improving the quality of the data product available to the user. Nonetheless, operating a highquality geomagnetic observatory is non-trivial. This article gives a record...... of the current state of observatory instrumentation and methods, citing some of the general problems in the complex operation of geomagnetic observatories. It further gives an overview of recent improvements of observatory data quality based on presentation during 11th IAGA Assembly at Sopron and INTERMAGNET...

  6. Deep Space Climate Observatory (DSCOVR)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Deep Space Climate ObserVatoRy (DSCOVR) satellite is a NOAA operated asset at the first Lagrange (L1) point. The primary space weather instrument is the PlasMag...

  7. Seafloor Observatory Science: a Review

    Directory of Open Access Journals (Sweden)

    L. Beranzoli

    2006-06-01

    Full Text Available The ocean exerts a pervasive influence on Earth’s environment. It is therefore important that we learn how this system operates (NRC, 1998b; 1999. For example, the ocean is an important regulator of climate change (e.g., IPCC, 1995. Understanding the link between natural and anthropogenic climate change and ocean circulation is essential for predicting the magnitude and impact of future changes in Earth’s climate. Understanding the ocean, and the complex physical, biological, chemical, and geological systems operating within it, should be an important goal for the opening decades of the 21st century. Another fundamental reason for increasing our understanding of ocean systems is that the global economy is highly dependent on the ocean (e.g., for tourism, fisheries, hydrocarbons, and mineral resources (Summerhayes, 1996. The establishment of a global network of seafloor observatories will help to provide the means to accomplish this goal. These observatories will have power and communication capabilities and will provide support for spatially distributed sensing systems and mobile platforms. Sensors and instruments will potentially collect data from above the air-sea interface to below the seafloor. Seafloor observatories will also be a powerful complement to satellite measurement systems by providing the ability to collect vertically distributed measurements within the water column for use with the spatial measurements acquired by satellites while also providing the capability to calibrate remotely sensed satellite measurements (NRC, 2000. Ocean observatory science has already had major successes. For example the TAO array has enabled the detection, understanding and prediction of El Niño events (e.g., Fujimoto et al., 2003. This paper is a world-wide review of the new emerging “Seafloor Observatory Science”, and describes both the scientific motivations for seafloor observatories and the technical solutions applied to their architecture. A

  8. Norwegian Ocean Observatory Network (NOON)

    Science.gov (United States)

    Ferré, Bénédicte; Mienert, Jürgen; Winther, Svein; Hageberg, Anne; Rune Godoe, Olav; Partners, Noon

    2010-05-01

    The Norwegian Ocean Observatory Network (NOON) is led by the University of Tromsø and collaborates with the Universities of Oslo and Bergen, UniResearch, Institute of Marine Research, Christian Michelsen Research and SINTEF. It is supported by the Research Council of Norway and oil and gas (O&G) industries like Statoil to develop science, technology and new educational programs. Main topics relate to ocean climate and environment as well as marine resources offshore Norway from the northern North Atlantic to the Arctic Ocean. NOON's vision is to bring Norway to the international forefront in using cable based ocean observatory technology for marine science and management, by establishing an infrastructure that enables real-time and long term monitoring of processes and interactions between hydrosphere, geosphere and biosphere. This activity is in concert with the EU funded European Strategy Forum on Research Infrastructures (ESFRI) roadmap and European Multidisciplinary Seafloor Observation (EMSO) project to attract international leading research developments. NOON envisions developing towards a European Research Infrastructure Consortium (ERIC). Beside, the research community in Norway already possesses a considerable marine infrastructure that can expand towards an international focus for real-time multidisciplinary observations in times of rapid climate change. PIC The presently established cable-based fjord observatory, followed by the establishment of a cable-based ocean observatory network towards the Arctic from an O&G installation, will provide invaluable knowledge and experience necessary to make a successful larger cable-based observatory network at the Norwegian and Arctic margin (figure 1). Access to large quantities of real-time observation from the deep sea, including high definition video, could be used to provide the public and future recruits to science a fascinating insight into an almost unexplored part of the Earth beyond the Arctic Circle

  9. Space astrophysical observatory 'Orion-2'

    International Nuclear Information System (INIS)

    Gurzadyan, G.A.; Jarakyan, A.L.; Krmoyan, M.N.; Kashin, A.L.; Loretsyan, G.M.; Ohanesyan, J.B.

    1976-01-01

    Ultraviolet spectrograms of a large number of faint stars up to 13sup(m) were obtained in the wavelengths 2000-5000 A by means of the space observatory 'Orion-2' installed in the spaceship 'Soyuz-13' with two spacemen on board. The paper deals with a description of the operation modes of this observatory, the designs and basic schemes of the scientific and auxiliary device and the method of combining the work of the flight engineer and the automation system of the observatory itself. It also treats of the combination of the particular parts of 'Orion-2' observatory on board the spaceship and the measures taken to provide for its normal functioning in terms of the space flight. A detailed description is given of the optical, electrical and mechanical schemes of the devices - meniscus telescope with an objective prism, stellar diffraction spectrographs, single-coordinate and two-coordinate stellar and solar transducers, control panel, control systems, etc. The paper also provides the functional scheme of astronavigation, six-wheel stabilization, the design of mounting (assembling) the stabilized platform carrying the telescopes and the drives used in it. Problems relating to the observation program in orbit, the ballistic provision of initial data, and control of the operation of the observatory are also dealt with. In addition, the paper carries information of the photomaterials used, the methods of their energy calibration, standardization and the like. Matters of pre-start tests of apparatus, the preparation of the spacemen for conducting astronomical observations with the given devices, etc. are likewise dwelt on. The paper ends with a brief survey of the results obtained and the elaboration of the observed material. (Auth.)

  10. Keep calm and carry on: A crisis communication study of Cadbury and McDonalds

    Directory of Open Access Journals (Sweden)

    Telang Achyut

    2016-04-01

    Full Text Available Many organizations, at some point or another, have to face a crisis situation. In that scenario, the way in which the organization communicates makes or breaks the organization’s success in dealing with the crisis. Especially after the emergence of the social media, the impact of crisis communication on the process of successful crisis management has become even greater than before. Organizations have to take the initiative, to be proactive and create a plan for crisis communication. This paper is focused on the comparative study of the communication approaches followed by Cadbury and McDonalds during a period when the companies were dealing with a crisis. The findings of the content analysis show that a company should respond to the crisis as quickly as possible to avoid loss in terms of sales. The initial statement of the companies during a crisis should be clear, positive and through the right channel to help the company regain its reputation on the market. Advertising is the best way to convey the message across the world because the crisis situation that has come up in one market can soon catch-up in the other markets where the company operates. The company has to connect with the consumers on emotional grounds because the crisis breaks down the faith of the consumers in the company. The recovery actions that support the statements also play an important role during the crisis situation. By following the above-mentioned communication strategies, organizations can achieve damage control as well as turn the crisis into an opportunity to grow.

  11. Volcanism, Iron, and Phytoplankton in the Heard and McDonald Islands Region, Southern Indian Ocean

    Science.gov (United States)

    Coffin, M. F.; Arculus, R. J.; Bowie, A. R.; Chase, Z.; Robertson, R.; Trull, T. W.; Heobi in2016 v01 Shipboard Party, T.

    2016-12-01

    Phytoplankton supply approximately half of the oxygen in Earth's atmosphere, and iron supply limits the growth of phytoplankton in the anemic Southern Ocean. Situated entirely within the Indian Ocean sector of the Southern Ocean are Australia's only active subaerial volcanoes, Heard and McDonald islands (HIMI) on the central Kerguelen Plateau, a large igneous province. Widespread fields of submarine volcanoes, some of which may be active, extend for distances of up to several hundred kilometers from the islands. The predominantly eastward-flowing Antarctic Circumpolar Current sweeps across the central Kerguelen Plateau, and extensive blooms of phytoplankton are observed on the Plateau down-current of HIMI. The goal of RV Investigator voyage IN2016_V01, conducted in January/February 2016, is to test the hypothesis that hydrothermal fluids, which cool active submarine volcanoes in the HIMI region, ascend from the seafloor and fertilise surface waters with iron, thereby enhancing biological productivity beginning with phytoplankton. Significant initial shipboard results include: Documentation, for the first time, of the role of active HIMI and nearby submarine volcanoes in supplying iron to the Southern Ocean. Nearshore waters had elevated dissolved iron levels. Although biomass was not correspondingly elevated, fluorescence induction data indicated highly productive resident phytoplankton. Discovery of >200 acoustic plumes emanating from the seafloor and ascending up to tens of meters into the water column near HIMI. Deep tow camera footage shows bubbles rising from the seafloor in an acoustic plume field north of Heard Island. Mapping 1,000 km2 of uncharted seafloor around HIMI. Submarine volcanic edifices punctuate the adjacent seafloor, and yielded iron-rich rocks similar to those found on HIMI, respectively. Acoustic plumes emanating from some of these features suggest active seafloor hydrothermal systems.

  12. Commissioning of the IDS Neutron Detector and $\\beta$-decay fast-timing studies at IDS

    CERN Document Server

    Piersa, Monika

    2016-01-01

    The following report describes my scientific activities performed during the Summer Student Programme at ISOLDE. The main part of my project was focused on commissioning the neutron detector dedicated to nuclear decay studies at ISOLDE Decay Station (IDS). I have participated in all the steps needed to make it operational for the IS609 experiment. In the testing phase, we obtained expected detector response and calibrations confirmed its successful commissioning. The detector was mounted in the desired geometry at IDS and used in measurements of the beta-delayed neutron emission of $^8$He. After completing aforementioned part of my project, I became familiar with the fast-timing method. This technique was applied at IDS in the IS610 experiment performed in June 2016 to explore the structure of neutron-rich $^{130-134}$Sn nuclei. Since the main part of my PhD studies will be the analysis of data collected in this experiment, the second part of my project was dedicated to acquiring knowledge about technical de...

  13. The Magnetic Observatory Buildings at the Royal Observatory, Cape

    Science.gov (United States)

    Glass, I. S.

    2015-10-01

    During the 1830s there arose a strong international movement, promoted by Carl Friedrich Gauss and Alexander von Humboldt, to characterise the earth's magnetic field. By 1839 the Royal Society in London, driven by Edward Sabine, had organised a "Magnetic Crusade" - the establishment of a series of magnetic and meteorological observatories around the British Empire, including New Zealand, Australia, St Helena and the Cape. This article outlines the history of the latter installation, its buildings and what became of them.

  14. The MicroObservatory Net

    Science.gov (United States)

    Brecher, K.; Sadler, P.

    1994-12-01

    A group of scientists, engineers and educators based at the Harvard-Smithsonian Center for Astrophysics (CfA) has developed a prototype of a small, inexpensive and fully integrated automated astronomical telescope and image processing system. The project team is now building five second generation instruments. The MicroObservatory has been designed to be used for classroom instruction by teachers as well as for original scientific research projects by students. Probably in no other area of frontier science is it possible for a broad spectrum of students (not just the gifted) to have access to state-of-the-art technologies that would allow for original research. The MicroObservatory combines the imaging power of a cooled CCD, with a self contained and weatherized reflecting optical telescope and mount. A microcomputer points the telescope and processes the captured images. The MicroObservatory has also been designed to be used as a valuable new capture and display device for real time astronomical imaging in planetariums and science museums. When the new instruments are completed in the next few months, they will be tried with high school students and teachers, as well as with museum groups. We are now planning to make the MicroObservatories available to students, teachers and other individual users over the Internet. We plan to allow the telescope to be controlled in real time or in batch mode, from a Macintosh or PC compatible computer. In the real-time mode, we hope to give individual access to all of the telescope control functions without the need for an "on-site" operator. Users would sign up for a specific period of time. In the batch mode, users would submit jobs for the telescope. After the MicroObservatory completed a specific job, the images would be e-mailed back to the user. At present, we are interested in gaining answers to the following questions: (1) What are the best approaches to scheduling real-time observations? (2) What criteria should be used

  15. Boscovich and the Brera Observatory .

    Science.gov (United States)

    Antonello, E.

    In the mid 18th century both theoretical and practical astronomy were cultivated in Milan by Barnabites and Jesuits. In 1763 Boscovich was appointed to the chair of mathematics of the University of Pavia in the Duchy of Milan, and the following year he designed an observatory for the Jesuit Collegium of Brera in Milan. The Specola was built in 1765 and it became quickly one of the main european observatories. We discuss the relation between Boscovich and Brera in the framework of a short biography. An account is given of the initial research activity in the Specola, of the departure of Boscovich from Milan in 1773 and his coming back just before his death.

  16. Compton Gamma-Ray Observatory

    Science.gov (United States)

    1991-01-01

    This photograph shows the Compton Gamma-Ray Observatory (GRO) being deployed by the Remote Manipulator System (RMS) arm aboard the Space Shuttle Atlantis during the STS-37 mission in April 1991. The GRO reentered Earth atmosphere and ended its successful mission in June 2000. For nearly 9 years, the GRO Burst and Transient Source Experiment (BATSE), designed and built by the Marshall Space Flight Center (MSFC), kept an unblinking watch on the universe to alert scientists to the invisible, mysterious gamma-ray bursts that had puzzled them for decades. By studying gamma-rays from objects like black holes, pulsars, quasars, neutron stars, and other exotic objects, scientists could discover clues to the birth, evolution, and death of stars, galaxies, and the universe. The gamma-ray instrument was one of four major science instruments aboard the Compton. It consisted of eight detectors, or modules, located at each corner of the rectangular satellite to simultaneously scan the entire universe for bursts of gamma-rays ranging in duration from fractions of a second to minutes. In January 1999, the instrument, via the Internet, cued a computer-controlled telescope at Las Alamos National Laboratory in Los Alamos, New Mexico, within 20 seconds of registering a burst. With this capability, the gamma-ray experiment came to serve as a gamma-ray burst alert for the Hubble Space Telescope, the Chandra X-Ray Observatory, and major gound-based observatories around the world. Thirty-seven universities, observatories, and NASA centers in 19 states, and 11 more institutions in Europe and Russia, participated in the BATSE science program.

  17. Extending and implementing the Persistent ID pillars

    Science.gov (United States)

    Car, Nicholas; Golodoniuc, Pavel; Klump, Jens

    2017-04-01

    The recent double decade anniversary of scholarly persistent identifier use has triggered journal special editions such as "20 Years of Persistent Identifiers". For such a publication, it is apt to consider the longevity of some persistent identifier (PID) mechanisms (Digital Object Identifiers) and the partial disappearance of others (Life Sciences IDs). We have previously postulated a set of "PID Pillars" [1] which are design principles aimed at ensuring PIDs can survive technology and social change and thus persist for the long term that we have drawn from our observations of PIDs at work over many years. The principles: describe how to ensure identifiers' system and organisation independence; codify the delivery of essential PID system functions; mandate a separation of PID functions from data delivery mechanisms; and require generation of policies detailing how change is handled. In this presentation, first we extend on our previous work of introducing the pillars by refining their descriptions, giving specific suggestions for each and presenting some work that addresses them. Second, we propose a baseline data model for persistent identifiers that, if used, would assist the separation of PID metadata and PID system functioning. This would allow PID system function specifics to change over time (e.g. resolver services or even resolution protocols) and yet preserve the PIDs themselves. Third, we detail our existing PID system — the PID Service [2] — that partially implements the pillars and describe both its successes and shortcomings. Finally, we describe our planned next-generation system that will aim to use the baseline data model and fully implement the pillars.

  18. Best practices for the implementation of the REAL ID Act.

    Science.gov (United States)

    2015-10-01

    The REAL ID Act specifies the minimum standards that must be used to produce and issue drivers license and : identification cards that are REAL ID compliant. Beginning in 2020, if a person does not possess a form of : identification that meets REA...

  19. IMI's CANCER-ID: Status of liquid biopsy standardization

    NARCIS (Netherlands)

    Pantel, Klaus; Terstappen, Leon W. M. M.; Baggiani, Barbara; Krahn, Thomas; Schlange, Thomas

    The CANCER-ID (www.cancer-id.eu) consortium was established in early 2015 with more than 30 partners as part of the Innovative Medicines Initiative (IMI), Europe's largest public-private partnership funded in equal parts by the European Union and the European Federation of Pharmaceutical Industries

  20. Evaluation of ID-PaGIA syphilis antibody test.

    Science.gov (United States)

    Naaber, Paul; Makoid, Ene; Aus, Anneli; Loivukene, Krista; Poder, Airi

    2009-01-01

    Laboratory diagnosis of syphilis is usually accomplished by serology. There are currently a large number of different commercial treponemal tests available that vary in format, sensitivity and specificity. To evaluate the ID-PaGIA Syphilis Antibody Test as an alternative to other specific treponemal tests for primary screening or confirmation of diagnosis. Serum samples from healthy adults (n = 100) were used for detection of specificity of ID-PaGIA. To evaluate sensitivity of ID-PaGIA serum samples (n = 101) from patients with confirmed or suspected syphilis were tested for syphilis antibodies with FTA-Abs IgM, ID-PaGIA, ELISA IgM and TPHA tests. No false-positive results were found with ID-PaGIA. Sensitivity of various treponemal tests was the following: FTA-Abs IgM: 95.5%, ID-PaGIA and ELISA IgM: 94%, and TPHA 75%. The positive and negative predictive values of ID-PaGIA were 100 and 89.5%, respectively. Compared with other treponemal tests ID-PaGIA has excellent sensitivity and specificity.

  1. Security analysis for biometric data in ID documents

    NARCIS (Netherlands)

    Schimke, S.; Kiltz, S.; Vielhauer, C.; Kalker, A.A.C.M.

    2005-01-01

    In this paper we analyze chances and challenges with respect to the security of using biometrics in ID documents. We identify goals for ID documents, set by national and international authorities, and discuss the degree of security, which is obtainable with the inclusion of biometric into documents

  2. A Contextual Model for Identity Management (IdM) Interfaces

    Science.gov (United States)

    Fuller, Nathaniel J.

    2014-01-01

    The usability of Identity Management (IdM) systems is highly dependent upon design that simplifies the processes of identification, authentication, and authorization. Recent findings reveal two critical problems that degrade IdM usability: (1) unfeasible techniques for managing various digital identifiers, and (2) ambiguous security interfaces.…

  3. 78 FR 65555 - Establishment of Class E Airspace; Salmon, ID

    Science.gov (United States)

    2013-11-01

    ...-0531; Airspace Docket No. 13-ANM-20] Establishment of Class E Airspace; Salmon, ID AGENCY: Federal... at the Salmon VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation aid, Salmon, ID, to facilitate vectoring of Instrument Flight Rules (IFR) aircraft under control of Salt Lake...

  4. Cyclin D1, Id1 and EMT in breast cancer

    International Nuclear Information System (INIS)

    Tobin, Nicholas P; Sims, Andrew H; Lundgren, Katja L; Lehn, Sophie; Landberg, Göran

    2011-01-01

    Cyclin D1 is a well-characterised cell cycle regulator with established oncogenic capabilities. Despite these properties, studies report contrasting links to tumour aggressiveness. It has previously been shown that silencing cyclin D1 increases the migratory capacity of MDA-MB-231 breast cancer cells with concomitant increase in 'inhibitor of differentiation 1' (ID1) gene expression. Id1 is known to be associated with more invasive features of cancer and with the epithelial-mesenchymal transition (EMT). Here, we sought to determine if the increase in cell motility following cyclin D1 silencing was mediated by Id1 and enhanced EMT-features. To further substantiate these findings we aimed to delineate the link between CCND1, ID1 and EMT, as well as clinical properties in primary breast cancer. Protein and gene expression of ID1, CCND1 and EMT markers were determined in MDA-MB-231 and ZR75 cells by western blot and qPCR. Cell migration and promoter occupancy were monitored by transwell and ChIP assays, respectively. Gene expression was analysed from publicly available datasets. The increase in cell migration following cyclin D1 silencing in MDA-MB-231 cells was abolished by Id1 siRNA treatment and we observed cyclin D1 occupancy of the Id1 promoter region. Moreover, ID1 and SNAI2 gene expression was increased following cyclin D1 knock-down, an effect reversed with Id1 siRNA treatment. Similar migratory and SNAI2 increases were noted for the ER-positive ZR75-1 cell line, but in an Id1-independent manner. In a meta-analysis of 1107 breast cancer samples, CCND1 low /ID1 high tumours displayed increased expression of EMT markers and were associated with reduced recurrence free survival. Finally, a greater percentage of CCND1 low /ID1 high tumours were found in the EMT-like 'claudin-low' subtype of breast cancer than in other subtypes. These results indicate that increased migration of MDA-MB-231 cells following cyclin D1 silencing can be mediated by Id

  5. Expression of Id2 in the Second Heart Field and Cardiac Defects in Id2 Knock-Out Mice

    NARCIS (Netherlands)

    Jongbloed, M. R. M.; Vicente-Steijn, R.; Douglas, Y. L.; Wisse, L. J.; Mori, K.; Yokota, Y.; Bartelings, M. M.; Schalij, M. J.; Mahtab, E. A.; Poelmann, R. E.; Gittenberger-De Groot, A. C.

    2011-01-01

    The inhibitor of differentiation Id2 is expressed in mesoderm of the second heart field, which contributes myocardial and mesenchymal cells to the primary heart tube. The role of Id2 in cardiac development is insufficiently known. Heart development was studied in sequential developmental stages in

  6. Applicability of McDonald 2010 and Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) 2016 Magnetic Resonance Imaging Criteria for the Diagnosis of Multiple Sclerosis in Sri Lanka.

    Science.gov (United States)

    Gamage, Sujani Madhurika Kodagoda; Wijeweera, Indunil; Wijesinghe, Priyangi; Adikari, Sanjaya Bandara; Fink, Katharina; Sominanda, Herath Mudiyanselage Ajith

    2018-05-31

    The magnetic resonance imaging in multiple sclerosis (MAGNIMS) group recently proposed guidelines to replace the existing dissemination-in-space criteria in McDonald 2010 magnetic resonance imaging (MRI) criteria for diagnosing multiple sclerosis. There has been insufficient research regarding their applicability in Asians. Objective of this study was to determine the sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of McDonald 2010 and MAGNIMS 2016 MRI criteria with the aim of verifying their applicability in Sri Lankan patients. Patients with clinically isolated syndrome diagnosed by consultant neurologists were recruited from five major neurology centers. Baseline and follow-up MRI scans were performed within 3 months from the initial presentation and at one year after baseline MRI, respectively. McDonald 2010 and MAGNIMS 2016 MRI criteria were applied to all MRI scans. Patients were followed-up for 2 years to assess the conversion to clinically definite multiple sclerosis (CDMS). The sensitivity, specificity, accuracy, PPV, and NPV for predicting the conversion to CDMS were calculated. Forty-two of 66 patients converted to CDMS. Thirty-seven fulfilled the McDonald 2010 MRI criteria, and 33 converted to CDMS. MAGNIMS 2016 MRI criteria were fulfilled by 29, with 28 converting to CDMS. The sensitivity, specificity, accuracy, PPV, and NPV were 78%, 83%, 64%, 89%, and 69%, respectively, for the McDonald 2010 criteria, and 67%, 96%, 77%, 96%, and 62% for the MAGNIMS 2016 MRI criteria. MAGNIMS 2016 MRI criteria were superior to McDonald 2010 MRI criteria in specificity, accuracy, and PPV, but inferior in sensitivity and NPV. Copyright © 2018 Korean Neurological Association.

  7. McDonald Criteria 2010 and 2005 Compared: Persistence of High Oligoclonal Band Prevalence Despite Almost Doubled Diagnostic Sensitivity

    Directory of Open Access Journals (Sweden)

    Philipp Schwenkenbecher

    2016-09-01

    Full Text Available The 2010 McDonald criteria were developed to allow a more rapid diagnosis of relapsing-remitting multiple sclerosis (MS by only one MRI of the brain. Although cerebrospinal fluid (CSF is not a mandatory part of the latest criteria, the evidence of an intrathecal humoral immunoreaction in the form of oligoclonal bands (OCB is crucial in the diagnostic workup. To date, the impact of the 2010 McDonald criteria on the prevalence of OCB has not been investigated. We retrospectively evaluated data of 325 patients with a clinical relapse suggestive of demyelination that were treated in a German university hospital between 2010 and 2015. One hundred thirty-six patients (42% were diagnosed with MS and 189 patients with CIS when the criteria of 2010 were applied. The criteria of 2005 allowed only 70 patients (22% to be designated as MS. In contrast, the prevalence of OCB was marginal affected in MS patients with 96% for the criteria of 2010 and 98.5% for the criteria of 2005. In conclusion, OCB are prevalent in most MS patients and reflect the chronic inflammatory nature of the disease. We recommend CSF examination to exclude alternative diagnoses and reevaluation of the diagnosis MS in patients with negative OCB.

  8. The McDonaldization of appraisal? Doctors' views of the early impacts of medical revalidation in the United Kingdom.

    Science.gov (United States)

    Archer, Julian; Nunn, Suzanne; Regan de Bere, Sam

    2017-09-01

    Medical regulation is rapidly changing with claims that systems such as revalidation/relicensing will reassure the public. Yet the impact of such initiatives is unknown. Using the principles of efficiency, calculability, predictability and control through technology, identified by Ritzer, and exampled by the McDonalds business model, we analyzed interviews with doctors between May 2012-Dec 2013 which focused on doctor experiences of appraisal and revalidation in SW England. The research found significant changes in appraisals since the launch of revalidation in December 2012. Appraisal has been standardized with a list of supporting information that must be collected by doctors. The success of implementation is measured in the numbers of appraisals completed but less is known about the quality of the appraisal itself. Such efficiencies have been supported by IT systems that themselves might be at risk of driving the process. There are potential advantages to McDonaldization including appraisals available to all, not just for doctors working in the NHS, and a potentially more appetizing recipe for their completion. As yet a state of McAppraisal has not been reached; with a complete transfer of trust in the doctor to trust in the appraisal process within revalidation. However policymakers will need to continue to ensure that regulatory initiatives, such as revalidation, are not just a process for their own sake. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. The value of conventional high-field MRI in MS in the light of the McDonald criteria: a literature review

    DEFF Research Database (Denmark)

    Larsen, Line Sofie Lunde; Larsson, H B W; Frederiksen, Jette Lautrup Battistini

    2010-01-01

    The diagnosis of MS is based on the revised McDonald criteria and is multidisciplinary. Both clinical and paraclinical measures are included. High-field magnetic resonance imaging (MRI) is becoming increasingly available and it is therefore necessary to clarify possible advantages of high-field MRI...... multiple sclerosis. Further larger studies of patients with clinically isolated syndromes are needed to settle the question of a diagnostic consequence of high-field imaging in MS. We suggest that the next revision of the McDonald diagnostic criteria include a recommendation of field strength....

  10. Observatory Sponsoring Astronomical Image Contest

    Science.gov (United States)

    2005-05-01

    Forget the headphones you saw in the Warner Brothers thriller Contact, as well as the guttural throbs emanating from loudspeakers at the Very Large Array in that 1997 movie. In real life, radio telescopes aren't used for "listening" to anything - just like visible-light telescopes, they are used primarily to make images of astronomical objects. Now, the National Radio Astronomy Observatory (NRAO) wants to encourage astronomers to use radio-telescope data to make truly compelling images, and is offering cash prizes to winners of a new image contest. Radio Galaxy Fornax A Radio Galaxy Fornax A Radio-optical composite image of giant elliptical galaxy NGC 1316, showing the galaxy (center), a smaller companion galaxy being cannibalized by NGC 1316, and the resulting "lobes" (orange) of radio emission caused by jets of particles spewed from the core of the giant galaxy Click on image for more detail and images CREDIT: Fomalont et al., NRAO/AUI/NSF "Astronomy is a very visual science, and our radio telescopes are capable of producing excellent images. We're sponsoring this contest to encourage astronomers to make the extra effort to turn good images into truly spectacular ones," said NRAO Director Fred K.Y. Lo. The contest, offering a grand prize of $1,000, was announced at the American Astronomical Society's meeting in Minneapolis, Minnesota. The image contest is part of a broader NRAO effort to make radio astronomical data and images easily accessible and widely available to scientists, students, teachers, the general public, news media and science-education professionals. That effort includes an expanded image gallery on the observatory's Web site. "We're not only adding new radio-astronomy images to our online gallery, but we're also improving the organization and accessibility of the images," said Mark Adams, head of education and public outreach (EPO) at NRAO. "Our long-term goal is to make the NRAO Image Gallery an international resource for radio astronomy imagery

  11. The high energy astronomy observatories

    Science.gov (United States)

    Neighbors, A. K.; Doolittle, R. F.; Halpers, R. E.

    1977-01-01

    The forthcoming NASA project of orbiting High Energy Astronomy Observatories (HEAO's) designed to probe the universe by tracing celestial radiations and particles is outlined. Solutions to engineering problems concerning HEAO's which are integrated, yet built to function independently are discussed, including the onboard digital processor, mirror assembly and the thermal shield. The principle of maximal efficiency with minimal cost and the potential capability of the project to provide explanations to black holes, pulsars and gamma-ray bursts are also stressed. The first satellite is scheduled for launch in April 1977.

  12. The Hartebeeshoek Radio Astronomy Observatory

    International Nuclear Information System (INIS)

    Nicolson, G.D.

    1986-01-01

    This article briefly discusses the questions, problems and study fields of the modern astronomer. Radioastronomy has made important contributions to the study of the evolution of stars and has given much information on the birth of stars while at the other extreme, studies of neutron stars and the radio emission from the remnants of supernova explosions have given further insight into the death of individual stars. Radio astronomical studies have learned astronomers much about the structure of the Milky way and some twenty years ago, in a search for new radio galaxies, quasars were discovered. Radioastronomy research in South Africa is carried out at the Hartebeesthoek Radio Astronomy Observatory

  13. The ultimate air shower observatory

    International Nuclear Information System (INIS)

    Jones, L.W.

    1981-01-01

    The possibility of constructing an international air shower observatory in the Himalayas is explored. A site at about 6500 m elevation (450 g/cm 2 ) would provide more definitive measurements of composition and early interaction properties of primaries above 10 16 eV than can be achieved with existing arrays. By supplementing a surface array with a Fly's Eye and muon detectors, information on the highest energy cosmic rays may be gained which is not possible in any other way. Potential sites, technical aspects, and logistical problems are explored

  14. BART: The Czech Autonomous Observatory

    Czech Academy of Sciences Publication Activity Database

    Nekola, Martin; Hudec, René; Jelínek, M.; Kubánek, P.; Štrobl, Jan; Polášek, Cyril

    2010-01-01

    Roč. 2010, Spec. Is. (2010), 103986/1-103986/5 ISSN 1687-7969. [Workshop on Robotic Autonomous Observatories. Málaga, 18.05.2009-21.05.2009] R&D Projects: GA ČR GA205/08/1207 Grant - others:ESA(XE) ESA-PECS project No. 98023; Spanish Ministry of Education and Science(ES) AP2003-1407 Institutional research plan: CEZ:AV0Z10030501 Keywords : robotic telescope * BART * gamma ray bursts Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www.hindawi.com/journals/aa/2010/103986.html

  15. Daily variation characteristics at polar geomagnetic observatories

    Science.gov (United States)

    Lepidi, S.; Cafarella, L.; Pietrolungo, M.; Di Mauro, D.

    2011-08-01

    This paper is based on the statistical analysis of the diurnal variation as observed at six polar geomagnetic observatories, three in the Northern and three in the Southern hemisphere. Data are for 2006, a year of low geomagnetic activity. We compared the Italian observatory Mario Zucchelli Station (TNB; corrected geomagnetic latitude: 80.0°S), the French-Italian observatory Dome C (DMC; 88.9°S), the French observatory Dumont D'Urville (DRV; 80.4°S) and the three Canadian observatories, Resolute Bay (RES; 83.0°N), Cambridge Bay (CBB; 77.0°N) and Alert (ALE, 87.2°N). The aim of this work was to highlight analogies and differences in daily variation as observed at the different observatories during low geomagnetic activity year, also considering Interplanetary Magnetic Field conditions and geomagnetic indices.

  16. EMSO: European multidisciplinary seafloor observatory

    Science.gov (United States)

    Favali, Paolo; Beranzoli, Laura

    2009-04-01

    EMSO has been identified by the ESFRI Report 2006 as one of the Research Infrastructures that European members and associated states are asked to develop in the next decades. It will be based on a European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the aim of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes, providing long time series data for the different phenomenon scales which constitute the new frontier for study of Earth interior, deep-sea biology and chemistry, and ocean processes. The development of an underwater network is based on past EU projects and is supported by several EU initiatives, such as the on-going ESONET-NoE, aimed at strengthening the ocean observatories' scientific and technological community. The EMSO development relies on the synergy between the scientific community and industry to improve European competitiveness with respect to countries such as USA, Canada and Japan. Within the FP7 Programme launched in 2006, a call for Preparatory Phase (PP) was issued in order to support the foundation of the legal and organisational entity in charge of building up and managing the infrastructure, and coordinating the financial effort among the countries. The EMSO-PP project, coordinated by the Italian INGV with participation by 11 institutions from as many European countries, started in April 2008 and will last four years.

  17. Worldwide R&D of Virtual Observatory

    Science.gov (United States)

    Cui, C. Z.; Zhao, Y. H.

    2008-07-01

    Virtual Observatory (VO) is a data intensive online astronomical research and education environment, taking advantages of advanced information technologies to achieve seamless and uniform access to astronomical information. The concept of VO was introduced in the late 1990s to meet the challenges brought up with data avalanche in astronomy. In the paper, current status of International Virtual Observatory Alliance, technical highlights from world wide VO projects are reviewed, a brief introduction of Chinese Virtual Observatory is given.

  18. Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    Science.gov (United States)

    Desprez, Pierre-Yves; Campisi, Judith

    2014-09-30

    A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a delivery vehicle comprising a product which modulates Id-1 or Id-2 expression.

  19. Byurakan Astrophysical Observatory as Cultural Centre

    Science.gov (United States)

    Mickaelian, A. M.; Farmanyan, S. V.

    2017-07-01

    NAS RA V. Ambartsumian Byurakan Astrophysical Observatory is presented as a cultural centre for Armenia and the Armenian nation in general. Besides being scientific and educational centre, the Observatory is famous for its unique architectural ensemble, rich botanical garden and world of birds, as well as it is one of the most frequently visited sightseeing of Armenia. In recent years, the Observatory has also taken the initiative of the coordination of the Cultural Astronomy in Armenia and in this field, unites the astronomers, historians, archaeologists, ethnographers, culturologists, literary critics, linguists, art historians and other experts. Keywords: Byurakan Astrophysical Observatory, architecture, botanic garden, tourism, Cultural Astronomy.

  20. FDIC Institution Directory (ID) -- Insured Insitution Download File

    Data.gov (United States)

    Federal Deposit Insurance Corporation — The FDIC's Institution Directory (ID) download file provides a list of all FDIC-insured institutions. The file includes demographic information related to the...

  1. ID card number detection algorithm based on convolutional neural network

    Science.gov (United States)

    Zhu, Jian; Ma, Hanjie; Feng, Jie; Dai, Leiyan

    2018-04-01

    In this paper, a new detection algorithm based on Convolutional Neural Network is presented in order to realize the fast and convenient ID information extraction in multiple scenarios. The algorithm uses the mobile device equipped with Android operating system to locate and extract the ID number; Use the special color distribution of the ID card, select the appropriate channel component; Use the image threshold segmentation, noise processing and morphological processing to take the binary processing for image; At the same time, the image rotation and projection method are used for horizontal correction when image was tilting; Finally, the single character is extracted by the projection method, and recognized by using Convolutional Neural Network. Through test shows that, A single ID number image from the extraction to the identification time is about 80ms, the accuracy rate is about 99%, It can be applied to the actual production and living environment.

  2. Identity Management ToolKit (IdM TK)

    Data.gov (United States)

    Department of Veterans Affairs — With the IdM TK, authorized users can search and view identity and exception information from the Administrative Data Repository (ADR). Specifically, users can view...

  3. A Good IDS Response Protocol of MANET Containment Strategies

    Science.gov (United States)

    Cheng, Bo-Chao; Chen, Huan; Tseng, Ryh-Yuh

    Much recent research concentrates on designing an Intrusion Detection System (IDS) to detect the misbehaviors of the malicious node in MANET with ad-hoc and mobility natures. However, without rapid and appropriate IDS response mechanisms performing follow-up management services, even the best IDS cannot achieve the desired primary goal of the incident response. A competent containment strategy is needed to limit the extent of an attack in the Incident Response Life Cycle. Inspired by the T-cell mechanisms in the human immune system, we propose an efficient MANET IDS response protocol (T-SecAODV) that can rapidly and accurately disseminate alerts of the malicious node attacks to other nodes so as to modify their AODV routing tables to isolate the malicious nodes. Simulations are conducted by the network simulator (Qualnet), and the experiment results indicate that T-SecAODV is able to spread alerts steadily while greatly reduce faulty rumors under simultaneous multiple malicious node attacks.

  4. O mundo de Ronald McDonald: sobre a marca publicitária e a socialidade midiática The world of Ronald McDonald: on the trademark and the mediatic sociality

    Directory of Open Access Journals (Sweden)

    Isleide Arruda Fontenelle

    2002-06-01

    Full Text Available O palhaço Ronald McDonald -- uma das imagens de marca da Corporação McDonald's -- é tomado como paradigma para pensarmos as relações entre mercado, mídia e entretenimento, as quais tem uma ligação direta com o que estamos conceituando como "socialidade midiática". Enquanto uma metáfora ideal de uma propaganda que parece não querer mais fazer sentido, a história do palhaço nos permite desvendar os sentidos contidos em duas das principais práticas do marketing moderno, a propaganda e a publicidade, revelando-nos como, entre o nonsense da propaganda contemporânea e uma publicidade que fundiu realidade e ilusão, há uma relação visceral entre mídia e publicidade, que estabelece uma nova forma de comunicação, na qual o sujeito torna-se apenas um meio para fins que ele sabe quais são, mas, paradoxalmente, age como se não soubesse. Tal paradoxo é revelador de uma forma de subjetividade profundamente marcada pela mídia enquanto agente socializador, na medida em que a atuação da mídia como mediador da socialidade contemporânea acabou por alterar o nosso universo perceptivo, saturando o nosso imaginário de uma forma radicalmente nova. Some-se a isso o fato de que a "socialidade midiática" implica uma nova forma de representação do sujeito no registro do "espetáculo", no sentido de que "estar na imagem é existir". Desnecessário dizer o quanto essas questões precisam ser contempladas pelos estudos contemporâneos sobre os processos de socialização e o quanto são desafiadoras para aqueles que atuam no universo da educação.The clown Ronald McDonald -- one of the trademarks of the McDonald's Corporation -- is taken as a paradigm to reflect upon the relations between market, media, and entertainment, which have a direct link with what we define as "mediatic sociality". As an ideal metaphor of an advertising that no longer seems to attempt to make sense, the story of the clown allows us to unveil the meanings contained

  5. Submarine glacial landforms and interactions with volcanism around Sub-Antarctic Heard and McDonald Islands

    Science.gov (United States)

    Picard, K.; Watson, S. J.; Fox, J. M.; Post, A.; Whittaker, J. M.; Lucieer, V.; Carey, R.; Coffin, M. F.; Hodgson, D.; Hogan, K.; Graham, A. G. C.

    2017-12-01

    Unravelling the glacial history of Sub-Antarctic islands can provide clues to past climate and Antarctic ice sheet stability. The glacial history of many sub-Antarctic islands is poorly understood, including the Heard and McDonald Islands (HIMI) located on the Kerguelen Plateau in the southern Indian Ocean. The geomorphologic development of HIMI has involved a combination of construction via hotspot volcanism and mechanical erosion caused by waves, weather, and glaciers. Today, the 2.5 km2 McDonald Islands are not glacierised; in contrast, the 368 km2 Heard Island has 12 major glaciers, some extending from the summit of 2813 m to sea level. Historical accounts from Heard Island suggest that the glaciers were more extensive in the 1850s to 1870s, and have retreated at least 12% (33.89 km2) since 1997. However, surrounding bathymetry suggests a much more extensive previous glaciation of the HIMI region that encompassed 9,585 km2, likely dating back at least to the Last Glacial Maximum (LGM) ca. 26.5 -19 ka. We present analyses of multibeam bathymetry and backscatter data, acquired aboard RV Investigator in early 2016, that support the previous existence of an extensive icecap. These data reveal widespread ice-marginal and subglacial features including moraines, over-deepened troughs, drumlins and crag-and-tails. Glacial landforms suggest paleo-ice flow directions and a glacial extent that are consistent with previously documented broad scale morphological features. We identify >660 iceberg keel scours in water depths ranging from 150 - 530 m. The orientations of the iceberg keel scours reflect the predominantly east-flowing Antarctic Circumpolar Current and westerly winds in the region. 40Ar/39Ar dating of volcanic rocks from submarine volcanoes around McDonald Islands suggests that volcanism and glaciation coincided. The flat-topped morphology of these volcanoes may result from lava-ice interaction or erosion by glaciers post eruption during a time of extensive ice

  6. The Antibody Response of Pregnant Cameroonian Women to VAR2CSA ID1-ID2a, a Small Recombinant Protein Containing the CSA-Binding Site

    Science.gov (United States)

    Babakhanyan, Anna; Leke, Rose G. F.; Salanti, Ali; Bobbili, Naveen; Gwanmesia, Philomina; Leke, Robert J. I.; Quakyi, Isabella A.; Chen, John J.; Taylor, Diane Wallace

    2014-01-01

    In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally acquire antibodies to ID1-ID2a and if antibodies to ID1-ID2a correlate with absence of placental malaria at delivery. Antibody levels to full-length VAR2CSA and ID1-ID2a were measured in plasma samples from 745 pregnant Cameroonian women, 144 Cameroonian men, and 66 US subjects. IgM levels and IgG avidity to ID1-ID2a were also determined. As expected, antibodies to ID1-ID2a were absent in US controls. Although pregnant Cameroonian women developed increasing levels of antibodies to full-length VAR2CSA during pregnancy, no increase in either IgM or IgG to ID1-ID2a was observed. Surprisingly, no differences in antibody levels to ID1-ID2a were detected between Cameroonian men and pregnant women. For example, in rural settings only 8–9% of males had antibodies to full-length VAR2CSA, but 90–96% had antibodies to ID1-ID2a. In addition, no significant difference in the avidity of IgG to ID1-ID2a was found between pregnant women and Cameroonian men, and no correlation between antibody levels at delivery and absence of placental malaria was found. Thus, the response to ID1-ID2a was not pregnancy specific, but predominantly against cross-reactivity epitopes, which may have been induced by other PfEMP1 antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a. PMID:24505415

  7. The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site.

    Directory of Open Access Journals (Sweden)

    Anna Babakhanyan

    Full Text Available In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally acquire antibodies to ID1-ID2a and if antibodies to ID1-ID2a correlate with absence of placental malaria at delivery. Antibody levels to full-length VAR2CSA and ID1-ID2a were measured in plasma samples from 745 pregnant Cameroonian women, 144 Cameroonian men, and 66 US subjects. IgM levels and IgG avidity to ID1-ID2a were also determined. As expected, antibodies to ID1-ID2a were absent in US controls. Although pregnant Cameroonian women developed increasing levels of antibodies to full-length VAR2CSA during pregnancy, no increase in either IgM or IgG to ID1-ID2a was observed. Surprisingly, no differences in antibody levels to ID1-ID2a were detected between Cameroonian men and pregnant women. For example, in rural settings only 8-9% of males had antibodies to full-length VAR2CSA, but 90-96% had antibodies to ID1-ID2a. In addition, no significant difference in the avidity of IgG to ID1-ID2a was found between pregnant women and Cameroonian men, and no correlation between antibody levels at delivery and absence of placental malaria was found. Thus, the response to ID1-ID2a was not pregnancy specific, but predominantly against cross-reactivity epitopes, which may have been induced by other PfEMP1 antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a.

  8. La certificazione professionale I&D in Europa

    OpenAIRE

    Franco, Augusta

    2003-01-01

    The statement points out the activity of I&D European associations in the field of competences' certification, in ECIA federation's area as well as in the national one. In the statement there are references on history and outcomes of DECIDoc project; objectives and operative stages of CERTIDoc project, promoted by ECIA; and enterprises of I&D associations in France, Spain, Germany and Italy. Secondly, it is illustrated the activity of Italian librarians and archivists associatio...

  9. Cronbach's [Alpha], Revelle's [Beta], and McDonald's [Omega][sub H]: Their Relations with Each Other and Two Alternative Conceptualizations of Reliability

    Science.gov (United States)

    Zinbarg, Richard E.; Revelle, William; Yovel, Iftah; Li, Wen

    2005-01-01

    We make theoretical comparisons among five coefficients--Cronbach's [alpha], Revelle's [beta], McDonald's [omega][sub h], and two alternative conceptualizations of reliability. Though many end users and psychometricians alike may not distinguish among these five coefficients, we demonstrate formally their nonequivalence. Specifically, whereas…

  10. [Effect of indications and pre-existing conditions on the result of McDonald's cervix-closure surgery].

    Science.gov (United States)

    Avar, Z; Tóth, B; Zacher, P

    1979-01-01

    Authors have performed the McDonald cerclage operation on 172 gravidae because of cervical incompetence. From these pregnancies 80.2 per cent of the infants have survived over the sixth day. While with operations performed on the basis of extended indications for surgery an effect of 56.5 per cent was achieved, it was in cases of classical ones 92.8 per cent. Two complicated cases are reported caused by blastospores or bacteria respectively, isolated also in the vaginal secretion which have ascended into the uterine cavity. Both cases resulted in fetal death and in a septic condition of the mother. It is emphasized that the normal vaginal bioflora is essential condition for the cervical suture.

  11. National Astronomical Observatory of Japan

    CERN Document Server

    Haubold, Hans J; UN/ESA/NASA Workshop on the International Heliophysical Year 2007 and Basic Space Science, hosted by the National Astronomical Observatory of Japan

    2010-01-01

    This book represents Volume II of the Proceedings of the UN/ESA/NASA Workshop on the International Heliophysical Year 2007 and Basic Space Science, hosted by the National Astronomical Observatory of Japan, Tokyo, 18 - 22 June, 2007. It covers two programme topics explored in this and past workshops of this nature: (i) non-extensive statistical mechanics as applicable to astrophysics, addressing q-distribution, fractional reaction and diffusion, and the reaction coefficient, as well as the Mittag-Leffler function and (ii) the TRIPOD concept, developed for astronomical telescope facilities. The companion publication, Volume I of the proceedings of this workshop, is a special issue in the journal Earth, Moon, and Planets, Volume 104, Numbers 1-4, April 2009.

  12. Autonomous Infrastructure for Observatory Operations

    Science.gov (United States)

    Seaman, R.

    This is an era of rapid change from ancient human-mediated modes of astronomical practice to a vision of ever larger time domain surveys, ever bigger "big data", to increasing numbers of robotic telescopes and astronomical automation on every mountaintop. Over the past decades, facets of a new autonomous astronomical toolkit have been prototyped and deployed in support of numerous space missions. Remote and queue observing modes have gained significant market share on the ground. Archives and data-mining are becoming ubiquitous; astroinformatic techniques and virtual observatory standards and protocols are areas of active development. Astronomers and engineers, planetary and solar scientists, and researchers from communities as diverse as particle physics and exobiology are collaborating on a vast range of "multi-messenger" science. What then is missing?

  13. TUM Critical Zone Observatory, Germany

    Science.gov (United States)

    Völkel, Jörg; Eden, Marie

    2014-05-01

    Founded 2011 the TUM Critical Zone Observatory run by the Technische Universität München and partners abroad is the first CZO within Germany. TUM CZO is both, a scientific as well as an education project. It is a watershed based observatory, but moving behind this focus. In fact, two mountainous areas are integrated: (1) The Ammer Catchment area as an alpine and pre alpine research area in the northern limestone Alps and forelands south of Munich; (2) the Otter Creek Catchment in the Bavarian Forest with a crystalline setting (Granite, Gneiss) as a mid mountainous area near Regensburg; and partly the mountainous Bavarian Forest National Park. The Ammer Catchment is a high energy system as well as a sensitive climate system with past glacial elements. The lithology shows mostly carbonates from Tertiary and Mesozoic times (e.g. Flysch). Source-to-sink processes are characteristic for the Ammer Catchment down to the last glacial Ammer Lake as the regional erosion and deposition base. The consideration of distal depositional environments, the integration of upstream and downstream landscape effects are characteristic for the Ammer Catchment as well. Long term datasets exist in many regards. The Otter Creek catchment area is developed in a granitic environment, rich in saprolites. As a mid mountainous catchment the energy system is facing lower stage. Hence, it is ideal comparing both of them. Both TUM CZO Catchments: The selected catchments capture the depositional environment. Both catchment areas include historical impacts and rapid land use change. Crosscutting themes across both sites are inbuilt. Questions of ability to capture such gradients along climosequence, chronosequence, anthroposequence are essential.

  14. Regional circulation around Heard and McDonald Islands and through the Fawn Trough, central Kerguelen Plateau

    Science.gov (United States)

    van Wijk, Esmee M.; Rintoul, Stephen R.; Ronai, Belinda M.; Williams, Guy D.

    2010-05-01

    The fine-scale circulation around the Heard and McDonald Islands and through the Fawn Trough, Kerguelen Plateau, is described using data from three high-resolution CTD sections, Argo floats and satellite maps of chlorophyll a, sea surface temperature (SST) and absolute sea surface height (SSH). We confirm that the Polar Front (PF) is split into two branches over the Kerguelen Plateau, with the NPF crossing the north-eastern limits of our survey carrying 25 Sv to the southeast. The SPF was associated with a strong eastward-flowing jet carrying 12 Sv of baroclinic transport through the deepest part of Fawn Trough (relative to the bottom). As the section was terminated midway through the trough this estimate is very likely to be a lower bound for the total transport. We demonstrate that the SPF contributes to the Fawn Trough Current identified by previous studies. After exiting the Fawn Trough, the SPF crossed Chun Spur and continued as a strong north-westward flowing jet along the eastern flank of the Kerguelen Plateau before turning offshore between 50°S and 51.5°S. Measured bottom water temperatures suggest a deep water connection between the northern and southern parts of the eastern Kerguelen Plateau indicating that the deep western boundary current continues at least as far north as 50.5°S. Analysis of satellite altimetry derived SSH streamlines demonstrates a southward shift of both the northern and southern branches of the Polar Front from 1994 to 2004. In the direct vicinity of the Heard and McDonald islands, cool waters of southern origin flow along the Heard Island slope and through the Eastern Trough bringing cold Winter Water (WW) onto the plateau. Complex topography funnels flow through canyons, deepens the mixed layer and increases productivity, resulting in this area being the preferred foraging region for a number of satellite-tracked land-based predators.

  15. Use of the 2010 McDonald criteria can facilitate early diagnosis of pediatric multiple sclerosis in a predominantly black cohort.

    Science.gov (United States)

    Williams, Mitchel T; Tapos, Daniela O; Juhász, Csaba

    2014-12-01

    Pediatric-onset multiple sclerosis represents around 3-5% of all patients with multiple sclerosis. Both the 2005 and 2010 McDonald criteria for multiple sclerosis have been suggested for the possible use in pediatric-onset multiple sclerosis. Modifications incorporated into the 2010 criteria enabled the fulfillment of dissemination in time to be met with the initial magnetic resonance imaging. The present study was designed to compare the diagnostic sensitivity of these criteria at initial presentation, the time to fulfilling them, and secondary effects of ethnicity in pediatric-onset multiple sclerosis. Twenty-five children with clinically definite multiple sclerosis (mean age, 14.6 ± 3.1 years; 15 girls) from a single center between 2005 and 2012 were analyzed using both the 2005 and 2010 McDonald criteria based on initial clinical presentation and neuroimaging findings comparing diagnostic sensitivity, time interval to meet diagnosis, and ethnicity. Initial multiple sclerosis diagnosis rates applying the 2005 McDonald criteria were 32% compared with 92% for the 2010 criteria (P = 0.0003). The mean time after initial signs until the 2005 and 2010 McDonald criteria for multiple sclerosis were met was 5.0 vs 0.7 months, respectively (P = 0.001). Time to diagnosis using the 2010 criteria was shorter in black children than the European white (P = 0.005). The 2010 McDonald criteria are an appropriate tool for the timely diagnosis of pediatric multiple sclerosis, especially in black children, potentially allowing an earlier initiation of disease-modifying therapy. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Heard Island and McDonald Islands Acoustic Plumes: Split-beam Echo sounder and Deep Tow Camera Observations of Gas Seeps on the Central Kerguelen Plateau

    Science.gov (United States)

    Watson, S. J.; Spain, E. A.; Coffin, M. F.; Whittaker, J. M.; Fox, J. M.; Bowie, A. R.

    2016-12-01

    Heard and McDonald islands (HIMI) are two active volcanic edifices on the Central Kerguelen Plateau. Scientists aboard the Heard Earth-Ocean-Biosphere Interactions voyage in early 2016 explored how this volcanic activity manifests itself near HIMI. Using Simrad EK60 split-beam echo sounder and deep tow camera data from RV Investigator, we recorded the distribution of seafloor emissions, providing the first direct evidence of seabed discharge around HIMI, mapping >244 acoustic plume signals. Northeast of Heard, three distinct plume clusters are associated with bubbles (towed camera) and the largest directly overlies a sub-seafloor opaque zone (sub-bottom profiler) with >140 zones observed within 6.5 km. Large temperature anomalies did not characterize any of the acoustic plumes where temperature data were recorded. We therefore suggest that these plumes are cold methane seeps. Acoustic properties - mean volume backscattering and target strength - and morphology - height, width, depth to surface - of plumes around McDonald resembled those northeast of Heard, also suggesting gas bubbles. We observed no bubbles on extremely limited towed camera data around McDonald; however, visibility was poor. The acoustic response of the plumes at different frequencies (120 kHz vs. 18 kHz), a technique used to classify water column scatterers, differed between HIMI, suggestiing dissimilar target size (bubble radii) distributions. Environmental context and temporal characteristics of the plumes differed between HIMI. Heard plumes were concentrated on flat, sediment rich plains, whereas around McDonald plumes emanated from sea knolls and mounds with hard volcanic seafloor. The Heard plumes were consistent temporally, while the McDonald plumes varied temporally possibly related to tides or subsurface processes. Our data and analyses suggest that HIMI acoustic plumes were likely caused by gas bubbles; however, the bubbles may originate from two or more distinct processes.

  17. Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome.

    Science.gov (United States)

    Huss, André M; Halbgebauer, Steffen; Öckl, Patrick; Trebst, Corinna; Spreer, Annette; Borisow, Nadja; Harrer, Andrea; Brecht, Isabel; Balint, Bettina; Stich, Oliver; Schlegel, Sabine; Retzlaff, Nele; Winkelmann, Alexander; Roesler, Romy; Lauda, Florian; Yildiz, Özlem; Voß, Elke; Muche, Rainer; Rauer, Sebastian; Bergh, Florian Then; Otto, Markus; Paul, Friedemann; Wildemann, Brigitte; Kraus, Jörg; Ruprecht, Klemens; Stangel, Martin; Buttmann, Mathias; Zettl, Uwe K; Tumani, Hayrettin

    2016-12-01

    The majority of patients presenting with a first clinical symptom suggestive of multiple sclerosis (MS) do not fulfill the MRI criteria for dissemination in space and time according to the 2010 revision of the McDonald diagnostic criteria for MS and are thus classified as clinically isolated syndrome (CIS). To re-evaluate the utility of cerebrospinal fluid (CSF) analysis in the context of the revised McDonald criteria from 2010, we conducted a retrospective multicenter study aimed at determining the prevalence and predictive value of oligoclonal IgG bands (OCBs) in patients with CIS. Patients were recruited from ten specialized MS centers in Germany and Austria. We collected data from 406 patients; at disease onset, 44/406 (11 %) fulfilled the McDonald 2010 criteria for MS. Intrathecal IgG OCBs were detected in 310/362 (86 %) of CIS patients. Those patients were twice as likely to convert to MS according to McDonald 2010 criteria as OCB-negative individuals (hazard ratio = 2.1, p = 0.0014) and in a shorter time period of 25 months (95 % CI 21-34) compared to 47 months in OCB-negative individuals (95 % CI 36-85). In patients without brain lesions at first attack and presence of intrathecal OCBs (30/44), conversion rate to MS was 60 % (18/30), whereas it was only 21 % (3/14) in those without OCBs. Our data confirm that in patients with CIS the risk of conversion to MS substantially increases if OCBs are present at onset. CSF analysis definitely helps to evaluate the prognosis in patients who do not have MS according to the revised McDonald criteria.

  18. Observatory data and the Swarm mission

    DEFF Research Database (Denmark)

    Macmillan, S.; Olsen, Nils

    2013-01-01

    products. We describe here the preparation of the data set of ground observatory hourly mean values, including procedures to check and select observatory data spanning the modern magnetic survey satellite era. We discuss other possible combined uses of satellite and observatory data, in particular those......The ESA Swarm mission to identify and measure very accurately the different magnetic signals that arise in the Earth’s core, mantle, crust, oceans, ionosphere and magnetosphere, which together form the magnetic field around the Earth, has increased interest in magnetic data collected on the surface...... of the Earth at observatories. The scientific use of Swarm data and Swarm-derived products is greatly enhanced by combination with observatory data and indices. As part of the Swarm Level-2 data activities plans are in place to distribute such ground-based data along with the Swarm data as auxiliary data...

  19. Solar Imagery - Photosphere - Sunspot Drawings - McMath-Hulbert Observatory

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The McMath-Hulbert Observatory is a decommissioned solar observatory in Lake Angelus, Michigan, USA. It was established in 1929 as a private observatory by father...

  20. EMSO: European Multidisciplinary Seafloor Observatory

    Science.gov (United States)

    Favali, P.; Partnership, Emso

    2009-04-01

    EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. EMSO will reply also to the need expressed in the frame of GMES (Global Monitoring for Environment and Security) to develop a marine segment integrated in the in situ and satellite global monitoring system. The EMSO development relays upon the synergy between the scientific community and the industry to improve the European competitiveness with respect to countries like USA/Canada, NEPTUNE, VENUS and MARS projects, Taiwan, MACHO project, and Japan, DONET project. In Europe the development of an underwater network is based on previous EU-funded projects since early '90, and presently supported by EU initiatives. The EMSO infrastructure will constitute the extension to the sea of the land-based networks. Examples of data recorded by seafloor observatories will be presented. EMSO is presently at the stage of Preparatory Phase (PP), funded in the EC FP7 Capacities Programme. The project has started in April 2008 and will last 4 years with the participation of 12 Institutions representing 12 countries. EMSO potential will be significantly increased also with the interaction with other Research Infrastructures addressed to Earth Science. 2. IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph Waldmann); IMI-Irish Marine Institute (Ireland, ref. Michael Gillooly); UTM-CSIC-Unidad de

  1. EMSO: European Multidisciplinary Seafloor Observatory

    Science.gov (United States)

    Favali, Paolo

    2010-05-01

    EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap (Report 2006, http://cordis.europa.eu/esfri/roadmap.htm), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. The development of an underwater network is based on previous EU-funded projects since early '90 and is being supported by several EU initiatives, as the on-going ESONET-NoE, coordinated by IFREMER (2007-2011, http://www.esonet-emso.org/esonet-noe/), and aims at gathering together the Research Community of the Ocean Observatories. In 2006 the FP7 Capacities Programme launched a call for Preparatory Phase (PP) projects, that will provide the support to create the legal and organisational entities in charge of managing the infrastructures, and coordinating the financial effort among the countries. Under this call the EMSO-PP project was approved in 2007 with the coordination of INGV and the participation of other 11 Institutions of 11 countries. The project has started in April 2008 and will last 4 years. The EMSO is a key-infrastructure both for Ocean Sciences and for Solid Earth Sciences. In this respect it will enhance and complement profitably the capabilities of other European research infrastructures such as EPOS, ERICON-Aurora Borealis, and SIOS. The perspective of the synergy among EMSO and other ESFRI Research Infrastructures will be outlined. EMSO Partners: IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph

  2. The Malaysian Robotic Solar Observatory (P29)

    Science.gov (United States)

    Othman, M.; Asillam, M. F.; Ismail, M. K. H.

    2006-11-01

    Robotic observatory with small telescopes can make significant contributions to astronomy observation. They provide an encouraging environment for astronomers to focus on data analysis and research while at the same time reducing time and cost for observation. The observatory will house the primary 50cm robotic telescope in the main dome which will be used for photometry, spectroscopy and astrometry observation activities. The secondary telescope is a robotic multi-apochromatic refractor (maximum diameter: 15 cm) which will be housed in the smaller dome. This telescope set will be used for solar observation mainly in three different wavelengths simultaneously: the Continuum, H-Alpha and Calcium K-line. The observatory is also equipped with an automated weather station, cloud & rain sensor and all-sky camera to monitor the climatic condition, sense the clouds (before raining) as well as to view real time sky view above the observatory. In conjunction with the Langkawi All-Sky Camera, the observatory website will also display images from the Malaysia - Antarctica All-Sky Camera used to monitor the sky at Scott Base Antarctica. Both all-sky images can be displayed simultaneously to show the difference between the equatorial and Antarctica skies. This paper will describe the Malaysian Robotic Observatory including the systems available and method of access by other astronomers. We will also suggest possible collaboration with other observatories in this region.

  3. Aliénation et idéologie

    OpenAIRE

    Kanabus, Benoît; Popa, Délia

    2017-01-01

    Dès lors, on entend mieux la question sur laquelle se referment les mille pages du Marx : « La pensée de Marx nous place devant la question abyssale : qu’est-ce que la vie » ? Cette question peut être reposée à nouveaux frais à l’âge du capitalisme avancé, où, comme le notait Adorno, la vie est devenue « l’idéologie de sa propre absence ». La recherche d’un autre rapport à l’idéologie vient alors prendre le relais de la lutte anti-idéologique de la théorie critique. Cette recherche part du po...

  4. Magnetic observations at Geophysical Observatory Paratunka IKIR FEB RAS: tasks, possibilities and future prospects

    Science.gov (United States)

    Khomutov, Sergey Y.

    2017-10-01

    Continuous magnetic measurements at Geophysical Observatory "Paratunka" (PET) of IKIR FEB RAS are performed since 1967. In the new millennium analogue magnetometers were modernized to digital, the technologies of absolute observations were changed, the data processing was completely transferred to computers, and the status of INTERMAGNET observatory was obtained. Currently, the observatory uses the following magnetometers: (a) for absolute observations - DIflux LEMI-203 (theodolite 3T2KP) and Mag-01 (theodolite Wild-T1), Overhauser magnetometers POS-1 and GSM-19W; (b) for variation measurements - fluxgate magnetometers FGE-DTU, FRG-601 and MAGDAS (installed under international agreements of IKIR), vector magnetometers dIdD GSM-19FD and POS-4 with Overhauser sensors and coil systems, scalar magnetometer GSM-90 and induction magnetometer STELAB. During Spring-Autumn season dIdD also is installed at remote station "Karymshina" at distance of 15 km from Observatory. There is monitoring system for monitoring of conditions in which magnetic observations are performed, including the semi-professional weather stations Davis Vantage Pro2 and WS2000 and a network of digital temperature sensors DS19B20 located at various points in magnetic pavilions and outdoor. All measurements are synchronized with the UTC. The results of observations are collected by the IKIR data server from the recorders and loggers, including in real-time. Specialized software was developed (based on MATLAB and Octave packages), which allows automatic and semi-automatic processing of data, the comparison of the results from different magnetometers and presenting final data in formats, defined by international standards, including INTERMAGNET. Significant efforts of observatory staff are direct to archive (raw) magnetic data, a significant part of which has not been entirely processed, is not presented in international data centers and is still not available to the scientific community. Digital images of

  5. Magnetic observations at Geophysical Observatory Paratunka IKIR FEB RAS: tasks, possibilities and future prospects

    Directory of Open Access Journals (Sweden)

    Khomutov Sergey Y.

    2017-01-01

    Full Text Available Continuous magnetic measurements at Geophysical Observatory “Paratunka” (PET of IKIR FEB RAS are performed since 1967. In the new millennium analogue magnetometers were modernized to digital, the technologies of absolute observations were changed, the data processing was completely transferred to computers, and the status of INTERMAGNET observatory was obtained. Currently, the observatory uses the following magnetometers: (a for absolute observations – DIflux LEMI-203 (theodolite 3T2KP and Mag-01 (theodolite Wild-T1, Overhauser magnetometers POS-1 and GSM-19W; (b for variation measurements – fluxgate magnetometers FGE-DTU, FRG-601 and MAGDAS (installed under international agreements of IKIR, vector magnetometers dIdD GSM-19FD and POS-4 with Overhauser sensors and coil systems, scalar magnetometer GSM-90 and induction magnetometer STELAB. During Spring-Autumn season dIdD also is installed at remote station “Karymshina” at distance of 15 km from Observatory. There is monitoring system for monitoring of conditions in which magnetic observations are performed, including the semi-professional weather stations Davis Vantage Pro2 and WS2000 and a network of digital temperature sensors DS19B20 located at various points in magnetic pavilions and outdoor. All measurements are synchronized with the UTC. The results of observations are collected by the IKIR data server from the recorders and loggers, including in real-time. Specialized software was developed (based on MATLAB and Octave packages, which allows automatic and semi-automatic processing of data, the comparison of the results from different magnetometers and presenting final data in formats, defined by international standards, including INTERMAGNET. Significant efforts of observatory staff are direct to archive (raw magnetic data, a significant part of which has not been entirely processed, is not presented in international data centers and is still not available to the scientific

  6. Robotic Software for the Thacher Observatory

    Science.gov (United States)

    Lawrence, George; Luebbers, Julien; Eastman, Jason D.; Johnson, John A.; Swift, Jonathan

    2018-06-01

    The Thacher Observatory—a research and educational facility located in Ojai, CA—uses a 0.7 meter telescope to conduct photometric research on a variety of targets including eclipsing binaries, exoplanet transits, and supernovae. Currently, observations are automated using commercial software. In order to expand the flexibility for specialized scientific observations and to increase the educational value of the facility on campus, we are adapting and implementing the custom observatory control software and queue scheduling developed for the Miniature Exoplanet Radial Velocity Array (MINERVA) to the Thacher Observatory. We present the design and implementation of this new software as well as its demonstrated functionality on the Thacher Observatory.

  7. Interoperability of Heliophysics Virtual Observatories

    Science.gov (United States)

    Thieman, J.; Roberts, A.; King, T.; King, J.; Harvey, C.

    2008-01-01

    If you'd like to find interrelated heliophysics (also known as space and solar physics) data for a research project that spans, for example, magnetic field data and charged particle data from multiple satellites located near a given place and at approximately the same time, how easy is this to do? There are probably hundreds of data sets scattered in archives around the world that might be relevant. Is there an optimal way to search these archives and find what you want? There are a number of virtual observatories (VOs) now in existence that maintain knowledge of the data available in subdisciplines of heliophysics. The data may be widely scattered among various data centers, but the VOs have knowledge of what is available and how to get to it. The problem is that research projects might require data from a number of subdisciplines. Is there a way to search multiple VOs at once and obtain what is needed quickly? To do this requires a common way of describing the data such that a search using a common term will find all data that relate to the common term. This common language is contained within a data model developed for all of heliophysics and known as the SPASE (Space Physics Archive Search and Extract) Data Model. NASA has funded the main part of the development of SPASE but other groups have put resources into it as well. How well is this working? We will review the use of SPASE and how well the goal of locating and retrieving data within the heliophysics community is being achieved. Can the VOs truly be made interoperable despite being developed by so many diverse groups?

  8. The Arecibo Observatory Space Academy

    Science.gov (United States)

    Rodriguez-Ford, Linda A.; Fernanda Zambrano Marin, Luisa; Aponte Hernandez, Betzaida; Soto, Sujeily; Rivera-Valentin, Edgard G.

    2016-10-01

    The Arecibo Observatory Space Academy (AOSA) is an intense fifteen-week pre-college research program for qualified high school students residing in Puerto Rico, which includes ten days for hands-on, on site research activities. Our mission is to prepare students for their professional careers by allowing them to receive an independent and collaborative research experience on topics related to the multidisciplinary field of space science. Our objectives are to (1) supplement the student's STEM education via inquiry-based learning and indirect teaching methods, (2) immerse students in an ESL environment, further developing their verbal and written presentation skills, and (3) foster in every student an interest in the STEM fields by harnessing their natural curiosity and knowledge in order to further develop their critical thinking and investigation skills. Students interested in participating in the program go through an application, interview and trial period before being offered admission. They are welcomed as candidates the first weeks, and later become cadets while experiencing designing, proposing, and conducting research projects focusing in fields like Physics, Astronomy, Geology, Chemistry, and Engineering. Each individual is evaluated with program compatibility based on peer interaction, preparation, participation, and contribution to class, group dynamics, attitude, challenges, and inquiry. This helps to ensure that specialized attention can be given to students who demonstrate a dedication and desire to learn. Deciding how to proceed in the face of setbacks and unexpected problems is central to the learning experience. At the end of the semester, students present their research to the program mentors, peers, and scientific staff. This year, AOSA students also focused on science communication and were trained by NASA's FameLab. Students additionally presented their research at this year's International Space Development Conference (ISDC), which was held in

  9. Pro-Amateur Observatories as a Significant Resource for Professional Astronomers - Taurus Hill Observatory

    Science.gov (United States)

    Haukka, H.; Hentunen, V.-P.; Nissinen, M.; Salmi, T.; Aartolahti, H.; Juutilainen, J.; Vilokki, H.

    2013-09-01

    Taurus Hill Observatory (THO), observatory code A95, is an amateur observatory located in Varkaus, Finland. The observatory is maintained by the local astronomical association of Warkauden Kassiopeia [8]. THO research team has observed and measured various stellar objects and phenomena. Observatory has mainly focuse d on asteroid [1] and exoplanet light curve measurements, observing the gamma rays burst, supernova discoveries and monitoring [2]. We also do long term monitoring projects [3]. THO research team has presented its research work on previous EPSC meetings ([4], [5],[6], [7]) and got very supportive reactions from the European planetary science community. The results and publications that pro-amateur based observatories, like THO, have contributed, clearly demonstrates that pro-amateurs area significant resource for the professional astronomers now and even more in the future.

  10. Magdalena Ridge Observatory Interferometer: Status Update

    National Research Council Canada - National Science Library

    Creech-Eakman, M. J; Bakker, E. J; Buscher, D. F; Coleman, T. A; Haniff, C. A; Jurgenson, C. A; Klinglesmith, III, D. A; Parameswariah, C. B; Romero, V. D; Shtromberg, A. V; Young, J. S

    2006-01-01

    The Magdalena Ridge Observatory Interferometer (MROI) is a ten element optical and near-infrared imaging interferometer being built in the Magdalena mountains west of Socorro, NM at an altitude of 3230 m...

  11. Ten years of the Spanish Virtual Observatory

    Science.gov (United States)

    Solano, E.

    2015-05-01

    The main objective of the Virtual Observatory (VO) is to guarantee an easy and efficient access and analysis of the information hosted in astronomical archives. The Spanish Virtual Observatory (SVO) is a project that was born in 2004 with the goal of promoting and coordinating the VO-related activities at national level. SVO is also the national contact point for the international VO initiatives, in particular the International Virtual Observatory Alliance (IVOA) and the Euro-VO project. The project, led by Centro de Astrobiología (INTA-CSIC), is structured around four major topics: a) VO compliance of astronomical archives, b) VO-science, c) VO- and data mining-tools, and d) Education and outreach. In this paper I will describe the most important results obtained by the Spanish Virtual Observatory in its first ten years of life as well as the future lines of work.

  12. The Astrophysical Multimessenger Observatory Network (AMON)

    Science.gov (United States)

    Smith. M. W. E.; Fox, D. B.; Cowen, D. F.; Meszaros, P.; Tesic, G.; Fixelle, J.; Bartos, I.; Sommers, P.; Ashtekar, Abhay; Babu, G. Jogesh; hide

    2013-01-01

    We summarize the science opportunity, design elements, current and projected partner observatories, and anticipated science returns of the Astrophysical Multimessenger Observatory Network (AMON). AMON will link multiple current and future high-energy, multimessenger, and follow-up observatories together into a single network, enabling near real-time coincidence searches for multimessenger astrophysical transients and their electromagnetic counterparts. Candidate and high-confidence multimessenger transient events will be identified, characterized, and distributed as AMON alerts within the network and to interested external observers, leading to follow-up observations across the electromagnetic spectrum. In this way, AMON aims to evoke the discovery of multimessenger transients from within observatory subthreshold data streams and facilitate the exploitation of these transients for purposes of astronomy and fundamental physics. As a central hub of global multimessenger science, AMON will also enable cross-collaboration analyses of archival datasets in search of rare or exotic astrophysical phenomena.

  13. Astronomy projects in ruins as observatory obliterated

    CERN Multimedia

    Bradley, M

    2003-01-01

    Canberra bushfires have gutted the Mount Stromlo Observatory causing the flames destroyed five telescopes, the workshop, eight staff homes and the main dome, causing more than $20 million in damage (1 page).

  14. In Brief: Deep-sea observatory

    Science.gov (United States)

    Showstack, Randy

    2008-11-01

    The first deep-sea ocean observatory offshore of the continental United States has begun operating in the waters off central California. The remotely operated Monterey Accelerated Research System (MARS) will allow scientists to monitor the deep sea continuously. Among the first devices to be hooked up to the observatory are instruments to monitor earthquakes, videotape deep-sea animals, and study the effects of acidification on seafloor animals. ``Some day we may look back at the first packets of data streaming in from the MARS observatory as the equivalent of those first words spoken by Alexander Graham Bell: `Watson, come here, I need you!','' commented Marcia McNutt, president and CEO of the Monterey Bay Aquarium Research Institute, which coordinated construction of the observatory. For more information, see http://www.mbari.org/news/news_releases/2008/mars-live/mars-live.html.

  15. The Farid and Moussa Raphael Observatory

    International Nuclear Information System (INIS)

    Hajjar, R

    2017-01-01

    The Farid and Moussa Raphael Observatory (FMRO) at Notre Dame University Louaize (NDU) is a teaching, research, and outreach facility located at the main campus of the university. It located very close to the Lebanese coast, in an urbanized area. It features a 60-cm Planewave CDK telescope, and instruments that allow for photometric and spetroscopic studies. The observatory currently has one thinned, back-illuminated CCD camera, used as the main imager along with Johnson-Cousin and Sloan photometric filters. It also features two spectrographs, one of which is a fiber fed echelle spectrograph. These are used with a dedicated CCD. The observatory has served for student projects, and summer schools for advanced undergraduate and graduate students. It is also made available for use by the regional and international community. The control system is currently being configured for remote observations. A number of long-term research projects are also being launched at the observatory. (paper)

  16. Identification of Staphylococcus species and subspecies with the MicroScan Pos ID and Rapid Pos ID panel systems.

    Science.gov (United States)

    Kloos, W E; George, C G

    1991-01-01

    The accuracies of the MicroScan Pos ID and Rapid Pos ID panel systems (Baxter Diagnostic Inc., MicroScan Division, West Sacramento, Calif.) were compared with each other and with the accuracies of conventional methods for the identification of 25 Staphylococcus species and 4 subspecies. Conventional methods included those used in the original descriptions of species and subspecies and DNA-DNA hybridization. The Pos ID panel uses a battery of 18 tests, and the Rapid Pos ID panel uses a battery of 42 tests for the identification of Staphylococcus species. The Pos ID panel has modified conventional and chromogenic tests that can be read after 15 to 48 h of incubation; the Rapid Pos ID panel has tests that use fluorogenic substrates or fluorometric indicators, and test results can be read after 2 h of incubation in the autoSCAN-W/A. Results indicated that both MicroScan systems had a high degree of congruence (greater than or equal to 90%) with conventional methods for the species S. capitis, S. aureus, S. auricularis, S. saprophyticus, S. cohnii, S. arlettae, S. carnosus, S. lentus, and S. sciuri and, in particular, the subspecies S. capitis subsp. capitis and S. cohnii subsp. cohnii. The Rapid Pos ID panel system also had greater than or equal to 90% congruence with conventional methods for S. epidermidis, S. caprae, S. warneri subsp. 2, S. xylosus, S. kloosii, and S. caseolyticus. For both MicroScan systems, congruence with conventional methods was 80 to 90% for S. haemolyticus subsp. 1, S. equorum, S. intermedius, and S. hyicus; and in addition, with the Rapid Pos ID panel system congruence was 80 to 89% for S. capitis subsp. ureolyticus, S. warneri subsp. 1, S. hominis, S. cohnii subsp. urealyticum, and S. simulans. The MicroScan systems identified a lower percentage (50 to 75%) of strains of S. lugdunensis, S. gallinarum, S. schleiferi, and S. chromogenes, although the addition of specific tests to the systems might increase the accuracy of identification

  17. Early German Plans for a Southern Observatory

    Science.gov (United States)

    Wolfschmidt, Gudrun

    As early as the 18th and 19th centuries, French and English observers were active in South Africa. Around the beginning of the 20th century the Heidelberg astronomer Max Wolf (1863-1932) proposed a southern observatory. In 1907 Hermann Carl Vogel (1841-1907), director of the Astrophysical Observatory Potsdam, suggested a southern station in Spain. His ideas for building an observatory in Windhuk for photographing the sky and measuring the solar constant were taken over by the Göttingen astronomers. In 1910 Karl Schwarzschild (1873-1916), after having visited the observatories in America, pointed out the usefulness of an observatory in South West Africa, where it would have better weather than in Germany and also give access to the southern sky. Seeing tests were begun in 1910 by Potsdam astronomers, but WW I stopped the plans. In 1928 Erwin Finlay-Freundlich (1885-1964), inspired by the Hamburg astronomer Walter Baade (1893-1960), worked out a detailed plan for a southern observatory with a reflecting telescope, spectrographs and an astrograph with an objective prism. Paul Guthnick (1879-1947), director of the Berlin observatory, in cooperation with APO Potsdam and Hamburg, made a site survey to Africa in 1929 and found the conditions in Windhuk to be ideal. Observations were started in the 1930s by Berlin and Breslau astronomers, but were stopped by WW II. In the 1950s, astronomers from Hamburg and The Netherlands renewed the discussion in the framework of European cooperation, and this led to the founding of ESO in 1963, as is well described by Blaauw (1991). Blaauw, Adriaan: ESO's Early History. The European Southern Observatory from Concept to Reality. Garching bei München: ESO 1991.

  18. The Pierre Auger Cosmic Ray Observatory

    Czech Academy of Sciences Publication Activity Database

    Aab, A.; Abreu, P.; Aglietta, M.; Boháčová, Martina; Chudoba, Jiří; Ebr, Jan; Grygar, Jiří; Mandát, Dušan; Nečesal, Petr; Palatka, Miroslav; Pech, Miroslav; Prouza, Michael; Řídký, Jan; Schovánek, Petr; Trávníček, Petr; Vícha, Jakub

    2015-01-01

    Roč. 798, Oct (2015), s. 172-213 ISSN 0168-9002 R&D Projects: GA MŠk(CZ) LG13007; GA MŠk(CZ) 7AMB14AR005; GA ČR(CZ) GA14-17501S Institutional support: RVO:68378271 Keywords : Pierre Auger Observatory * high energy cosmic rays * hybrid observatory * water Cherenkov detectors * air fluorescence detectors Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.200, year: 2015

  19. A Green Robotic Observatory for Astronomy Education

    Science.gov (United States)

    Reddy, Vishnu; Archer, K.

    2008-09-01

    With the development of robotic telescopes and stable remote observing software, it is currently possible for a small institution to have an affordable astronomical facility for astronomy education. However, a faculty member has to deal with the light pollution (observatory location on campus), its nightly operations and regular maintenance apart from his day time teaching and research responsibilities. While building an observatory at a remote location is a solution, the cost of constructing and operating such a facility, not to mention the environmental impact, are beyond the reach of most institutions. In an effort to resolve these issues we have developed a robotic remote observatory that can be operated via the internet from anywhere in the world, has a zero operating carbon footprint and minimum impact on the local environment. The prototype observatory is a clam-shell design that houses an 8-inch telescope with a SBIG ST-10 CCD detector. The brain of the observatory is a low draw 12-volt harsh duty computer that runs the dome, telescope, CCD camera, focuser, and weather monitoring. All equipment runs of a 12-volt AGM-style battery that has low lead content and hence more environmental-friendly to dispose. The total power of 12-14 amp/hrs is generated from a set of solar panels that are large enough to maintain a full battery charge for several cloudy days. This completely eliminates the need for a local power grid for operations. Internet access is accomplished via a high-speed cell phone broadband connection or satellite link eliminating the need for a phone network. An independent observatory monitoring system interfaces with the observatory computer during operation. The observatory converts to a trailer for transportation to the site and is converted to a semi-permanent building without wheels and towing equipment. This ensures minimal disturbance to local environment.

  20. Comparison of the optimized conditions for genotyping of ACE ID ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-19

    Oct 19, 2009 ... variants (Koyama et al., 2008). This method removed the chances of mistyping and gave 100% accuracy in the confirmation of ID heterozygotes but expenses of chromatography did not prove it to be cost effective. Normally, genomic DNA is used as template DNA for. PCR based studies. It is very difficult to ...

  1. Screening of Lactobacillus plantarum isolated from fermented idli ...

    African Journals Online (AJOL)

    Probiotics are defined as live microorganisms which when administered in adequate amounts confer a health benefit on the host. The objective of this study was to screen eight potential probiotic Lactobacillus plantarum strains from fermented idli batter using in vitro assays such as bile tolerance, acid tolerance, transit ...

  2. Enhancing privacy of users in eID schemes

    NARCIS (Netherlands)

    Shrishak, Kris; Erkin, Z.; Schaar, Remco

    2016-01-01

    In todays world transactions are increasingly being performed over the internetbut require identication of users as in face-to-face transactions. In order to facilitate eGovernance as well as other eCommerce services Electronic Identiation(eID) schemes, which intend to provide unique and reliable

  3. Comparison of the optimized conditions for genotyping of ACE ID ...

    African Journals Online (AJOL)

    ACE ID polymorphism is inevitable for genetic epidemiology of several cardiovascular and non cardiovascular diseases due to its direct influence on ACE activity level. In the present work, conditions were optimized for its analysis using conventional and direct blood PCR (DB PCR). Blood samples from nine normotensive ...

  4. Anmeldung in ILIAS ohne Uni-Login-ID

    OpenAIRE

    Schanz, Nadja

    2016-01-01

    Gewusst wie...! Online-Tutorial der Universitätsbibliothek Tübingen. Erklärt die Anmeldung in Ilias zu Führungen ohne Uni-Login-ID Online Tutorial from university library tuebingen. teaches how to register in Ilias for courses and guided tours without university login

  5. idRHa+ProMod - Rail Hardening Control System

    International Nuclear Information System (INIS)

    Ferro, L

    2016-01-01

    idRHa+ProMod is the process control system developed by Primetals Technologies to foresee the thermo-mechanical evolution and micro-structural composition of rail steels subjected to slack quenching into idRHa+ Rail Hardening equipments in a simulation environment. This tool can be used both off-line or in-line, giving the user the chance to test and study the best cooling strategies or letting the automatic control system free to adjust the proper cooling recipe. Optimization criteria have been tailored in order to determine the best cooling conditions according to the metallurgical requirements imposed by the main rail standards and also taking into account the elastoplastic bending phenomena occurring during all stages of the head hardening process. The computational core of idRHa+ProMod is a thermal finite element procedure coupled with special algorithms developed to work out the main thermo-physical properties of steel, to predict the non-isothermal austenite decomposition into all the relevant phases and subsequently to evaluate the amount of latent heat of transformation released, the compound thermal expansion coefficient and the amount of plastic deformation in the material. Air mist and air blades boundary conditions have been carefully investigated by means of pilot plant tests aimed to study the jet impingement on rail surfaces and the cooling efficiency at all working conditions. Heat transfer coefficients have been further checked and adjusted directly on field during commissioning. idRHa+ is a trademark of Primetals Technologies Italy Srl (paper)

  6. The Danish eID Case: Twenty years of Delay

    DEFF Research Database (Denmark)

    Hoff, Jens Villiam; Hoff, Frederik Villiam

    2010-01-01

    the technological, organizational and legal dimensions of eID in Denmark, and comparing these with a number of other European countries made it possible to explain this paradox. Thus, the three main reasons for the special route development has taken in Denmark seems to be concerns over privacy, lack...

  7. idRHa+ProMod - Rail Hardening Control System

    Science.gov (United States)

    Ferro, L.

    2016-03-01

    idRHa+ProMod is the process control system developed by Primetals Technologies to foresee the thermo-mechanical evolution and micro-structural composition of rail steels subjected to slack quenching into idRHa+ Rail Hardening equipments in a simulation environment. This tool can be used both off-line or in-line, giving the user the chance to test and study the best cooling strategies or letting the automatic control system free to adjust the proper cooling recipe. Optimization criteria have been tailored in order to determine the best cooling conditions according to the metallurgical requirements imposed by the main rail standards and also taking into account the elastoplastic bending phenomena occurring during all stages of the head hardening process. The computational core of idRHa+ProMod is a thermal finite element procedure coupled with special algorithms developed to work out the main thermo-physical properties of steel, to predict the non-isothermal austenite decomposition into all the relevant phases and subsequently to evaluate the amount of latent heat of transformation released, the compound thermal expansion coefficient and the amount of plastic deformation in the material. Air mist and air blades boundary conditions have been carefully investigated by means of pilot plant tests aimed to study the jet impingement on rail surfaces and the cooling efficiency at all working conditions. Heat transfer coefficients have been further checked and adjusted directly on field during commissioning. idRHa+ is a trademark of Primetals Technologies Italy Srl

  8. Student ID Cards: What You Should Know About Them

    Science.gov (United States)

    Hoffman, Jonathan; McGuire, Agnes C.

    1973-01-01

    Discusses the usefulness of photo ID cards for school security purposes, library control, student activities, and bus transportation control. Examines ways in which card costs can be reduced and the pros and cons of producing the cards at the school or of letting the work out. Problems involving card abuse and student rights are also considered.…

  9. Early German plans for southern observatories

    Science.gov (United States)

    Wolfschmidt, G.

    2002-07-01

    As early as the 18th and 19th centuries, French and English observers were active in South Africa. Around the beginning of the 20th century, Heidelberg and Potsdam astronomers proposed a southern observatory. Then Göttingen astronomers suggested building an observatory in Windhoek for photographing the sky and measuring the solar constant. In 1910 Karl Schwarzschild (1873-1916), after a visit to observatories in the United States, pointed out the usefulness of an observatory in South West Africa, in a climate superior to that in Germany, giving German astronomers access to the southern sky. Seeing tests were begun in 1910 by Potsdam astronomers, but WW I stopped the plans. In 1928 Erwin Finlay-Freundlich (1885-1964), inspired by the Hamburg astronomer Walter Baade (1893-1960), worked out a detailed plan for a southern observatory with a reflecting telescope, spectrographs and an astrograph with an objective prism. Paul Guthnick (1879-1947), director of the Berlin observatory, in cooperation with APO Potsdam and Hamburg, made a site survey to Africa in 1929 and found the conditions in Windhoek to be ideal. Observations were started in the 1930s by Berlin and Breslau astronomers, but were stopped by WW II. In the 1950s, astronomers from Hamburg and The Netherlands renewed the discussion in the framework of European cooperation, and this led to the founding of ESO in 1963.

  10. Observatories of Sawai Jai Singh II

    Science.gov (United States)

    Johnson-Roehr, Susan N.

    Sawai Jai Singh II, Maharaja of Amber and Jaipur, constructed five observatories in the second quarter of the eighteenth century in the north Indian cities of Shahjahanabad (Delhi), Jaipur, Ujjain, Mathura, and Varanasi. Believing the accuracy of his naked-eye observations would improve with larger, more stable instruments, Jai Singh reengineered common brass instruments using stone construction methods. His applied ingenuity led to the invention of several outsize masonry instruments, the majority of which were used to determine the coordinates of celestial objects with reference to the local horizon. During Jai Singh's lifetime, the observatories were used to make observations in order to update existing ephemerides such as the Zīj-i Ulugh Begī. Jai Singh established communications with European astronomers through a number of Jesuits living and working in India. In addition to dispatching ambassadorial parties to Portugal, he invited French and Bavarian Jesuits to visit and make use of the observatories in Shahjahanabad and Jaipur. The observatories were abandoned after Jai Singh's death in 1743 CE. The Mathura observatory was disassembled completely before 1857. The instruments at the remaining observatories were restored extensively during the nineteenth and twentieth centuries.

  11. The Russian-Ukrainian Observatories Network for the European Astronomical Observatory Route Project

    Science.gov (United States)

    Andrievsky, S. M.; Bondar, N. I.; Karetnikov, V. G.; Kazantseva, L. V.; Nefedyev, Y. A.; Pinigin, G. I.; Pozhalova, Zh. A.; Rostopchina-Shakhovskay, A. N.; Stepanov, A. V.; Tolbin, S. V.

    2011-09-01

    In 2004,the Center of UNESCO World Heritage has announced a new initiative "Astronomy & World Heritage" directed for search and preserving of objects,referred to astronomy,its history in a global value,historical and cultural properties. There were defined a strategy of thematic programme "Initiative" and general criteria for selecting of ancient astronomical objects and observatories. In particular, properties that are situated or have significance in relation to celestial objects or astronomical events; representations of sky and/or celestial bodies and astronomical events; observatories and instruments; properties closely connected with the history of astronomy. In 2005-2006,in accordance with the program "Initiative", information about outstanding properties connected with astronomy have been collected.In Ukraine such work was organized by astronomical expert group in Nikolaev Astronomical Observatory. In 2007, Nikolaev observatory was included to the Tentative List of UNESCO under # 5116. Later, in 2008, the network of four astronomical observatories of Ukraine in Kiev,Crimea, Nikolaev and Odessa,considering their high authenticities and integrities,was included to the Tentative List of UNESCO under # 5267 "Astronomical Observatories of Ukraine". In 2008-2009, a new project "Thematic Study" was opened as a successor of "Initiative". It includes all fields of astronomical heritage from earlier prehistory to the Space astronomy (14 themes in total). We present the Ukraine-Russian Observatories network for the "European astronomical observatory Route project". From Russia two observatories are presented: Kazan Observatory and Pulkovo Observatory in the theme "Astronomy from the Renaissance to the mid-twentieth century".The description of astronomical observatories of Ukraine is given in accordance with the project "Thematic study"; the theme "Astronomy from the Renaissance to the mid-twentieth century" - astronomical observatories in Kiev,Nikolaev and Odessa; the

  12. Proces zavádění nových výrobků společnosti McDonald ´s

    OpenAIRE

    Vaňková, Kateřina

    2010-01-01

    This Bachelor's thesis focuses on the way of introducing new products of the company McDonald's in the Czech Republic. It is divided into theoretical and practical part. The theoretical part of the thesis deals the fundamental terms of general marketing. These are: SWOT analysis, marketing communications, marketing strategies and communication mix. In the practical part of the thesis is presented the history of the company, the corporate social responsibility and the basic principles. The fol...

  13. Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria

    DEFF Research Database (Denmark)

    Filippi, Massimo; Preziosa, Paolo; Meani, Alessandro

    2018-01-01

    of the distinction between symptomatic and asymptomatic lesions was suggested. We compared the performance of the 2010 McDonald and 2016 MAGNIMS criteria for multiple sclerosis diagnosis in a large multicentre cohort of patients with CIS to provide evidence to guide revisions of multiple sclerosis diagnostic......, 2017, 571 patients with CIS were screened, of whom 368 met all study inclusion criteria. At the last evaluation (median 50·0 months [IQR 27·0-78·4]), 189 (51%) of 368 patients developed clinically definite multiple sclerosis. At 36 months, the two DIS criteria showed high sensitivity (2010 McDonald 0......·32-0·50], and similar AUC (0·63 [0·57-0·68]). Inclusion of optic nerve evaluation resulted in similar sensitivity (0·92 [0·87-0·96]), and slightly lower specificity (0·26 [0·18-0·34]) and AUC (0·59 [0·55-0·64]). AUC values were also similar for DIT (2010 McDonald 0·61 [0·55-0·67] and 2016 MAGNIMS 0·61 [0...

  14. Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer

    International Nuclear Information System (INIS)

    Sharma, Pankaj; Chinaranagari, Swathi; Patel, Divya; Carey, Jason; Chaudhary, Jaideep

    2012-01-01

    The inhibitor of DNA-binding (Id) proteins, Id1–4 are negative regulators of basic helix-loop-helix (bHLH) transcription factors. As key regulators of cell cycle and differentiation, expression of Id proteins are increasingly observed in many cancers and associated with aggressiveness of the disease. Of all the four Id proteins, the expression of Id1, Id2, and to a lesser extent, Id3 in prostate cancer and the underlying molecular mechanism is relatively well known. On the contrary, our previous results demonstrated that Id4 acts as a potential tumor suppressor in prostate cancer. In the present study, we extend these observations and demonstrate that Id4 is down-regulated in prostate cancer due to promoter hypermethylation. We used prostate cancer tissue microarrays to investigate Id4 expression. Methylation specific PCR on bisulfite treated DNA was used to determine methylation status of Id4 promoter in laser capture micro-dissected normal, stroma and prostate cancer regions. High Id4 expression was observed in the normal prostate epithelial cells. In prostate cancer, a stage-dependent decrease in Id4 expression was observed with majority of high grade cancers showing no Id4 expression. Furthermore, Id4 expression progressively decreased in prostate cancer cell line LNCaP and with no expression in androgen-insensitive LNCaP-C81 cell line. Conversely, Id4 promoter hypermethylation increased in LNCaP-C81 cells suggesting epigenetic silencing. In prostate cancer samples, loss of Id4 expression was also associated with promoter hypermethylation. Our results demonstrate loss of Id4 expression in prostate cancer due to promoter hypermethylation. The data strongly support the role of Id4 as a tumor suppressor

  15. The Fram Strait integrated ocean observatory

    Science.gov (United States)

    Fahrbach, E.; Beszczynska-Möller, A.; Rettig, S.; Rohardt, G.; Sagen, H.; Sandven, S.; Hansen, E.

    2012-04-01

    A long-term oceanographic moored array has been operated since 1997 to measure the ocean water column properties and oceanic advective fluxes through Fram Strait. While the mooring line along 78°50'N is devoted to monitoring variability of the physical environment, the AWI Hausgarten observatory, located north of it, focuses on ecosystem properties and benthic biology. Under the EU DAMOCLES and ACOBAR projects, the oceanographic observatory has been extended towards the innovative integrated observing system, combining the deep ocean moorings, multipurpose acoustic system and a network of gliders. The main aim of this system is long-term environmental monitoring in Fram Strait, combining satellite data, acoustic tomography, oceanographic measurements at moorings and glider sections with high-resolution ice-ocean circulation models through data assimilation. In future perspective, a cable connection between the Hausgarten observatory and a land base on Svalbard is planned as the implementation of the ESONET Arctic node. To take advantage of the planned cabled node, different technologies for the underwater data transmission were reviewed and partially tested under the ESONET DM AOEM. The main focus was to design and evaluate available technical solutions for collecting data from different components of the Fram Strait ocean observing system, and an integration of available data streams for the optimal delivery to the future cabled node. The main components of the Fram Strait integrated observing system will be presented and the current status of available technologies for underwater data transfer will be reviewed. On the long term, an initiative of Helmholtz observatories foresees the interdisciplinary Earth-Observing-System FRAM which combines observatories such as the long term deep-sea ecological observatory HAUSGARTEN, the oceanographic Fram Strait integrated observing system and the Svalbard coastal stations maintained by the Norwegian ARCTOS network. A vision

  16. 195-Year History of Mykolayiv Observatory: Events and People

    Directory of Open Access Journals (Sweden)

    Shulga, O.V.

    2017-01-01

    Full Text Available The basic stages of the history of the Mykolaiv Astronomical Observatory are shown. The main results of the Observatory activities are presented by the catalogs of star positions, major and minor planets in the Solar system, space objects in the Earth orbit. The information on the qualitative and quantitative structure of the Observatory, cooperation with the observatories of Ukraine and foreign countries as well as major projects carried out in the Observatory is provided.

  17. ESA innovation rescues Ultraviolet Observatory

    Science.gov (United States)

    1995-10-01

    experience to have the opportunity to do an in-depth review of operational procedures established in 1978 and be given the chance to streamline these through the application of the tools available to engineers and scientists in 1995." The innovative arrangements were designed and developed at the ESA IUE Observatory, which is located in Spain at ESA's Villafranca Satellite Tracking Station in Villanueva de la Canada near Madrid. As a result, ESA is now performing all of WE's science observations (16 hours per day) from the Villafranca station. All the processing of the observations transmitted by the satellite and the subsequent rapid data distribution to the research scientists world-wide is now done from Villafranca. NASA does maintain its role in the programme in the area of operational spacecraft maintenance support, satellite communications and data re-processing for IUE's Final Archive. Thus the IUE Project could be extended and the final IUE observing program can now be implemented. In particular, this will involve critical studies on comets (e,g. on Comet Hale-Bopp), on stellar wind structures, on the enigmatic mini-quasars (which are thought to power the nuclei of Active Galaxies), as well as performing pre- studies which will optimize the utilization of the Hubble Space Telescope. Prof. R.M. Bonnet, Director of the ESA Science Programme comments "I am quite pleased that we have been able to secure the extension of our support for the scientists in Europe and the world to this highly effective mission. Also the scientists can be proud of the utilization of IUE, with more than 3000 learned publications and 200 Doctoral dissertations based on data from IUE. Through this they demonstrate in turn to be very appreciative of our efforts in the Science Programme".

  18. An international network of magnetic observatories

    Science.gov (United States)

    Love, Jeffrey J.; Chulliat, A.

    2013-01-01

    Since its formation in the late 1980s, the International Real-Time Magnetic Observatory Network (INTERMAGNET), a voluntary consortium of geophysical institutes from around the world, has promoted the operation of magnetic observatories according to modern standards [eg. Rasson, 2007]. INTERMAGNET institutes have cooperatively developed infrastructure for data exchange and management ads well as methods for data processing and checking. INTERMAGNET institute have also helped to expand global geomagnetic monitoring capacity, most notably by assisting magnetic observatory institutes in economically developing countries by working directly with local geophysicists. Today the INTERMAGNET consortium encompasses 57 institutes from 40 countries supporting 120 observatories (see Figures 1a and 1b). INTERMAGNET data record a wide variety of time series signals related to a host of different physical processes in the Earth's interiors and in the Earth's surrounding space environment [e.g., Love, 2008]. Observatory data have always had a diverse user community, and to meet evolving demand, INTERMAGNET has recently coordinated the introduction of several new data services.

  19. The University of Montana's Blue Mountain Observatory

    Science.gov (United States)

    Friend, D. B.

    2004-12-01

    The University of Montana's Department of Physics and Astronomy runs the state of Montana's only professional astronomical observatory. The Observatory, located on nearby Blue Mountain, houses a 16 inch Boller and Chivens Cassegrain reflector (purchased in 1970), in an Ash dome. The Observatory sits just below the summit ridge, at an elevation of approximately 6300 feet. Our instrumentation includes an Op-Tec SSP-5A photoelectric photometer and an SBIG ST-9E CCD camera. We have the only undergraduate astronomy major in the state (technically a physics major with an astronomy option), so our Observatory is an important component of our students' education. Students have recently carried out observing projects on the photometry of variable stars and color photometry of open clusters and OB associations. In my poster I will show some of the data collected by students in their observing projects. The Observatory is also used for public open houses during the summer months, and these have become very popular: at times we have had 300 visitors in a single night.

  20. Determination of local chromatin composition by CasID.

    Science.gov (United States)

    Schmidtmann, Elisabeth; Anton, Tobias; Rombaut, Pascaline; Herzog, Franz; Leonhardt, Heinrich

    2016-09-02

    Chromatin structure and function are determined by a plethora of proteins whose genome-wide distribution is typically assessed by immunoprecipitation (ChIP). Here, we developed a novel tool to investigate the local chromatin environment at specific DNA sequences. We combined the programmable DNA binding of dCas9 with the promiscuous biotin ligase BirA* (CasID) to biotinylate proteins in the direct vicinity of specific loci. Subsequent streptavidin-mediated precipitation and mass spectrometry identified both known and previously unknown chromatin factors associated with repetitive telomeric, major satellite and minor satellite DNA. With super-resolution microscopy, we confirmed the localization of the putative transcription factor ZNF512 at chromocenters. The versatility of CasID facilitates the systematic elucidation of functional protein complexes and locus-specific chromatin composition.

  1. Zircaloy cladding ID/OD oxidation studies. Final report

    International Nuclear Information System (INIS)

    Westerman, R.E.; Hesson, G.M.

    1977-11-01

    The ID/OD oxide ratio that forms on Zircaloy tubing at temperatures relevant to postulated LOCA conditions was measured as a function of time, temperature, and distance from the rupture. The average ratio at the rupture position was less than unity, and decreased with decreasing test time and increasing distance from the point of rupture. The maximum observed ID/OD oxide ratio was 1.4. Ratios in excess of unity were typically found to be a consequence of the OD oxide being thinner than would have been anticipated from the nominal test conditions. Confirmatory data were also obtained on the isothermal oxidation kinetics of Zircaloy. These data are in good agreement with those obtained by other investigators and confirm the conservative nature of the Baker-Just equation that is required for use in licensing calculations

  2. ID-kaart on mugav ja praktiline dokument / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1949-

    2001-01-01

    Ilmunud ka: Severnoje Poberezhje 12. okt., lk. 2; Lääne Elu 13. okt., lk. 2; Hiiumaa 13. okt., lk. 2; Koit 16. okt., lk. 6; Nädaline 16. okt., lk. 4; Sakala 18. okt., lk. 2; Valgamaalane 18. okt., lk. 2; Pjarnuskii Ekspress 12. okt., lk. 2; Meie Maa 19. okt., lk. 2; Hiiu Leht 23. okt., lk. 2; Järva Teataja 30. okt., lk. 2. Siseministri nõunik Heiki Raudla ID-kaardist

  3. Time-and-ID-Based Proxy Reencryption Scheme

    OpenAIRE

    Mtonga, Kambombo; Paul, Anand; Rho, Seungmin

    2014-01-01

    Time- and ID-based proxy reencryption scheme is proposed in this paper in which a type-based proxy reencryption enables the delegator to implement fine-grained policies with one key pair without any additional trust on the proxy. However, in some applications, the time within which the data was sampled or collected is very critical. In such applications, for example, healthcare and criminal investigations, the delegatee may be interested in only some of the messages with some types sampled wi...

  4. ID based cryptography for secure cloud data storage

    OpenAIRE

    Kaaniche , Nesrine; Boudguiga , Aymen; Laurent , Maryline

    2013-01-01

    International audience; This paper addresses the security issues of storing sensitive data in a cloud storage service and the need for users to trust the commercial cloud providers. It proposes a cryptographic scheme for cloud storage, based on an original usage of ID-Based Cryptography. Our solution has several advantages. First, it provides secrecy for encrypted data which are stored in public servers. Second, it offers controlled data access and sharing among users, so that unauthorized us...

  5. Guinea pig ID-like families of SINEs.

    Science.gov (United States)

    Kass, David H; Schaetz, Brian A; Beitler, Lindsey; Bonney, Kevin M; Jamison, Nicole; Wiesner, Cathy

    2009-05-01

    Previous studies have indicated a paucity of SINEs within the genomes of the guinea pig and nutria, representatives of the Hystricognathi suborder of rodents. More recent work has shown that the guinea pig genome contains a large number of B1 elements, expanding to various levels among different rodents. In this work we utilized A-B PCR and screened GenBank with sequences from isolated clones to identify potentially uncharacterized SINEs within the guinea pig genome, and identified numerous sequences with a high degree of similarity (>92%) specific to the guinea pig. The presence of A-tails and flanking direct repeats associated with these sequences supported the identification of a full-length SINE, with a consensus sequence notably distinct from other rodent SINEs. Although most similar to the ID SINE, it clearly was not derived from the known ID master gene (BC1), hence we refer to this element as guinea pig ID-like (GPIDL). Using the consensus to screen the guinea pig genomic database (Assembly CavPor2) with Ensembl BlastView, we estimated at least 100,000 copies, which contrasts markedly to just over 100 copies of ID elements. Additionally we provided evidence of recent integrations of GPIDL as two of seven analyzed conserved GPIDL-containing loci demonstrated presence/absence variants in Cavia porcellus and C. aperea. Using intra-IDL PCR and sequence analyses we also provide evidence that GPIDL is derived from a hystricognath-specific SINE family. These results demonstrate that this SINE family continues to contribute to the dynamics of genomes of hystricognath rodents.

  6. ID'ing innate and innate-like lymphoid cells.

    Science.gov (United States)

    Verykokakis, Mihalis; Zook, Erin C; Kee, Barbara L

    2014-09-01

    The immune system can be divided into innate and adaptive components that differ in their rate and mode of cellular activation, with innate immune cells being the first responders to invading pathogens. Recent advances in the identification and characterization of innate lymphoid cells have revealed reiterative developmental programs that result in cells with effector fates that parallel those of adaptive lymphoid cells and are tailored to effectively eliminate a broad spectrum of pathogenic challenges. However, activation of these cells can also be associated with pathologies such as autoimmune disease. One major distinction between innate and adaptive immune system cells is the constitutive expression of ID proteins in the former and inducible expression in the latter. ID proteins function as antagonists of the E protein transcription factors that play critical roles in lymphoid specification as well as B- and T-lymphocyte development. In this review, we examine the transcriptional mechanisms controlling the development of innate lymphocytes, including natural killer cells and the recently identified innate lymphoid cells (ILC1, ILC2, and ILC3), and innate-like lymphocytes, including natural killer T cells, with an emphasis on the known requirements for the ID proteins. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Multinational History of Strasbourg Astronomical Observatory

    CERN Document Server

    Heck, André

    2005-01-01

    Strasbourg Astronomical Observatory is quite an interesting place for historians: several changes of nationality between France and Germany, high-profile scientists having been based there, big projects born or installed in its walls, and so on. Most of the documents circulating on the history of the Observatory and on related matters have however been so far poorly referenced, if at all. This made necessary the compilation of a volume such as this one, offering fully-documented historical facts and references on the first decades of the Observatory history, authored by both French and German specialists. The experts contributing to this book have done their best to write in a way understandable to readers not necessarily hyperspecialized in astronomy nor in the details of European history. After an introductory chapter by the Editor, contributions by Wolfschmidt and by Duerbeck respectively deal extensively with the German periods and review people and instrumentation, while another paper by Duerbeck is more...

  8. Internal validation of the RapidHIT® ID system.

    Science.gov (United States)

    Wiley, Rachel; Sage, Kelly; LaRue, Bobby; Budowle, Bruce

    2017-11-01

    Traditionally, forensic DNA analysis has required highly skilled forensic geneticists in a dedicated laboratory to generate short tandem repeat (STR) profiles. STR profiles are routinely used either to associate or exclude potential donors of forensic biological evidence. The typing of forensic reference samples has become more demanding, especially with the requirement in some jurisdictions to DNA profile arrestees. The Rapid DNA (RDNA) platform, the RapidHIT ® ID (IntegenX ® , Pleasanton, CA), is a fully automated system capable of processing reference samples in approximately 90min with minimal human intervention. Thus, the RapidHIT ID instrument can be deployed to non-laboratory environments (e.g., booking stations) and run by trained atypical personnel such as law enforcement. In order to implement the RapidHIT ID platform, validation studies are needed to define the performance and limitations of the system. Internal validation studies were undertaken with four early-production RapidHIT ID units. Reliable and concordant STR profiles were obtained from reference buccal swabs. Throughout the study, no contamination was observed. The overall first-pass success rate with an "expert-like system" was 72%, which is comparable to another current RDNA platform commercially available. The system's second-pass success rate (involving manual interpretation on first-pass inconclusive results) increased to 90%. Inhibitors (i.e., coffee, smoking tobacco, and chewing tobacco) did not appear to affect typing by the instrument system; however, substrate (i.e., swab type) did impact typing success. Additionally, one desirable feature not available with other Rapid systems is that in the event of a system failed run, a swab can be recovered and subsequently re-analyzed in a new sample cartridge. Therefore, rarely should additional sampling or swab consumption be necessary. The RapidHIT ID system is a robust and reliable tool capable of generating complete STR profiles within

  9. Hospital leadership perspectives on the contributions of Ronald McDonald Houses. Results from an international survey.

    Science.gov (United States)

    Lantz, Paula M; Rubin, Nicole; Mauery, D Richard

    2015-01-01

    The purpose of this paper is to describe an international survey of hospital executives and administrators' perspectives on the contributions of their affiliation with a Ronald McDonald House (RMH) as an example of accommodation in family-centered care to the hospital's mission, operations and patient experience. RMHs worldwide provided the names and e-mail addresses of the people holding key leadership positions in their main hospital partner, who in turn were invited to complete an internet-based survey (530 participants; response rate of 54.5 percent). Hospital leaders reported very positive opinions about the contributions of their RMHs affiliation to their ability to serve seriously ill children and their families. This included such important outcomes as increasing family integrity and family participation in care decisions; and decreasing psychosocial stress and hospital social work resource burdens associated with lodging, food, transportation and sibling support. Hospital chief executive offices (CEOs) and medical directors reported very strong and positive opinions regarding the value-added of their RMHs affiliation in many areas, including enhanced marketing of hospital specialty services and reduced length of stay. Survey response bias is a limitation, although the results are still useful in terms of identifying multiple ways in which RMHs are perceived as contributing to hospitals' operations and provision of family-centered care. Overall, the results suggest that, internationally, hospital leaders believe that RMHs play a key and valued role in their provision of family-centered care to seriously ill children and their families. Family accommodation is more than the simple provision of lodging and plays an integral role how hospitals approach family-centered care. This international study contributes to the general literature on the role of family accommodation in hospitals' provision of family-centered care and the specific and very sparse

  10. "Like a trip to McDonalds": a grounded theory study of patient experiences of day surgery.

    Science.gov (United States)

    Mottram, Anne

    2011-02-01

    The amount and complexity of (ambulatory) day surgery is rapidly expanding internationally. Nurses have a responsibility to provide quality care for day surgery patients. To do this they must understand all aspects of the patient experience. There is dearth of research into day surgery using a sociological frame of reference. The study investigated patients' experiences of day surgery using a sociological frame of reference. A qualitative study using the grounded theory approach was used. The study was based in two day surgery units in two urban public hospitals in the United Kingdom. 145 patients aged 18-70 years and 100 carers were purposely selected from the orthopaedic, ear nose and throat and general surgical lists. They were all English speaking and were of varied socio-economic background. The data was collected from 2004 to 2006. Semi-structured interviews were conducted on three occasions: before surgery, 48 h following surgery and one month following discharge. Permission was received from the Local Research Ethics Committee. Analysis of the data involved line-by-line analysis, compilation of key words and phrases (codes) and constant comparison of the codes until categories emerged. Patients liked day surgery and placed it within the wider societal context of efficiency and speed. Time was a major issue for them. They wished surgery, like all other aspects of their life to be a speedy process. They likened it to a McDonald's experience with its emphasis on speed, predictability and control. This study throws new light on patient experiences and offers an understanding of day surgery against a western culture which emphasises the importance of speed and efficiency. It is a popular choice for patients but at times it can be seen to be a mechanistic way of providing care. The implications for nurses to provide education and information to add to the quality of the patient experience are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. Chicago's Dearborn Observatory: a study in survival

    Science.gov (United States)

    Bartky, Ian R.

    2000-12-01

    The Dearborn Observatory, located on the Old University of Chicago campus from 1863 until 1888, was America's most promising astronomical facility when it was founded. Established by the Chicago Astronomical Society and directed by one of the country's most gifted astronomers, it boasted the largest telescope in the world and virtually unlimited operating funds. The Great Chicago Fire of 1871 destroyed its funding and demolished its research programme. Only via the sale of time signals and the heroic efforts of two amateur astronomers did the Dearborn Observatory survive.

  12. Geoelectric monitoring at the Boulder magnetic observatory

    Directory of Open Access Journals (Sweden)

    C. C. Blum

    2017-11-01

    Full Text Available Despite its importance to a range of applied and fundamental studies, and obvious parallels to a robust network of magnetic-field observatories, long-term geoelectric field monitoring is rarely performed. The installation of a new geoelectric monitoring system at the Boulder magnetic observatory of the US Geological Survey is summarized. Data from the system are expected, among other things, to be used for testing and validating algorithms for mapping North American geoelectric fields. An example time series of recorded electric and magnetic fields during a modest magnetic storm is presented. Based on our experience, we additionally present operational aspects of a successful geoelectric field monitoring system.

  13. Operation of the Pierre Auger Observatory

    International Nuclear Information System (INIS)

    Rodriguez Martino, Julio

    2011-01-01

    While the work to make data acquisition fully automatic continues, both the Fluorescence Detectors and the Surface Detectors of the Pierre Auger Observatory need some kind of attention from the local staff. In the first case, the telescopes are operated and monitored during the moonless periods. The ground array only needs monitoring, but the larger number of stations implies more variables to consider. AugerAccess (a high speed internet connection) will give the possibility of operating and monitoring the observatory from any place in the world. This arises questions about secure access, better control software and alarms. Solutions are already being tested and improved.

  14. The origin of the Hawaiian Volcano Observatory

    International Nuclear Information System (INIS)

    Dvorak, John

    2011-01-01

    I first stepped through the doorway of the Hawaiian Volcano Observatory in 1976, and I was impressed by what I saw: A dozen people working out of a stone-and-metal building perched at the edge of a high cliff with a spectacular view of a vast volcanic plain. Their primary purpose was to monitor the island's two active volcanoes, Kilauea and Mauna Loa. I joined them, working for six weeks as a volunteer and then, years later, as a staff scientist. That gave me several chances to ask how the observatory had started.

  15. SPASE and the Heliophysics Virtual Observatories

    Directory of Open Access Journals (Sweden)

    J R Thieman

    2010-02-01

    Full Text Available The Space Physics Archive Search and Extract (SPASE project has developed an information model for interoperable access and retrieval of data within the Heliophysics (also known as space and solar physics science community. The diversity of science data archives within this community has led to the establishment of many virtual observatories to coordinate the data pathways within Heliophysics subdisciplines, such as magnetospheres, waves, radiation belts, etc. The SPASE information model provides a semantic layer and common language for data descriptions so that searches might be made across the whole of the heliophysics data environment, especially through the virtual observatories.

  16. The origin of the Hawaiian Volcano Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Dvorak, John [University of Hawaii' s Institute for Astronomy (United States)

    2011-05-15

    I first stepped through the doorway of the Hawaiian Volcano Observatory in 1976, and I was impressed by what I saw: A dozen people working out of a stone-and-metal building perched at the edge of a high cliff with a spectacular view of a vast volcanic plain. Their primary purpose was to monitor the island's two active volcanoes, Kilauea and Mauna Loa. I joined them, working for six weeks as a volunteer and then, years later, as a staff scientist. That gave me several chances to ask how the observatory had started.

  17. Public relations for a national observatory

    Science.gov (United States)

    Finley, David G.

    The National Radio Astronomy Observatory (NRAO) is a government-funded organization providing state-of-the art observational facilities to the astronomical community on a peer-reviewed basis. In this role, the NRAO must address three principal constituencies with its public-relations efforts. These are: the astronomical community; the funding and legislative bodies of the Federal Government; and the general public. To serve each of these constituencies, the Observatory has developed a set of public-relations initiatives supported by public-relations and outreach professionals as well as by management and scientific staff members. The techniques applied and the results achieved in each of these areas are described.

  18. ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma

    International Nuclear Information System (INIS)

    Phi, Ji Hoon; Choi, Seung Ah; Lim, Sang-Hee; Lee, Joongyub; Wang, Kyu-Chang; Park, Sung-Hye; Kim, Seung-Ki

    2013-01-01

    The inhibitor of differentiation (ID) genes have been implicated as promoters of tumor progression and metastasis in many human cancers. The current study investigated the expression and functional roles of ID genes in seeding and prognosis of medulloblastoma. ID gene expression was screened in human medulloblastoma tissues. Knockdown of ID3 gene was performed in medulloblastoma cells in vitro. The expression of metastasis-related genes after ID3 knockdown was assessed. The effect of ID3 knockdown on tumor seeding was observed in an animal model in vivo. The survival of medulloblastoma patients was plotted according to the ID3 expression levels. Significantly higher ID3 expression was observed in medulloblastoma with cerebrospinal fluid seeding than tumors without seeding. Knockdown of ID3 decreased proliferation, increased apoptosis, and suppressed the migration of D283 medulloblastoma cells in vitro. In a seeding model of medulloblastoma, ID3 knockdown in vivo with shRNA inhibited the growth of primary tumors, prevented the development of leptomeningeal seeding, and prolonged animal survival. High ID3 expression was associated with shorter survival of medulloblastoma patients, especially in Group 4 medulloblastomas. High ID3 expression is associated with medullolbastoma seeding and is a poor prognostic factor, especially in patients with Group 4 tumors. ID3 may represent the metastatic/ aggressive phenotype of a subgroup of medulloblastoma

  19. 78 FR 25406 - Proposed Modification of Class E Airspace; Twin Falls, ID

    Science.gov (United States)

    2013-05-01

    ...) Global Positioning System (GPS) and the Instrument Landing System (ILS) or Localizer (LOC) standard... the earth. * * * * * ANM ID E5 Twin Falls, ID [Modified] Twin Falls Joslin Field-Magic Valley Regional...

  20. 78 FR 40382 - Modification of Class D and E Airspace; Twin Falls, ID

    Science.gov (United States)

    2013-07-05

    ... using the Navigation (RNAV) Global Positioning System (GPS) and the Instrument Landing System (ILS) or... or more above the surface of the earth. * * * * * ANM ID E5 Twin Falls, ID [Modified] Twin Falls...

  1. 77 FR 68065 - Amendment of Class D and Class E Airspace; Lewiston, ID

    Science.gov (United States)

    2012-11-15

    ... Measuring Equipment (VOR/ DME), and the Lewiston-Nez Perce Instrument Landing System (ILS) Localizer... feet or more above the surface of the earth. * * * * * ANM ID E5 Lewiston, ID [Modified] Lewiston-Nez...

  2. ID.alistic: identificatie met een touch voor de patiënt

    NARCIS (Netherlands)

    M. Wilschut; M. Zijlmans; Dr. L.S.G.L Wauben

    2017-01-01

    ID.alistic is een conceptuele patiëntidentificatie methode (middels een vingerafdrukscanner), ter vervanging van het polsbandjessysteem van het Albert Schweitzer ziekenhuis (ASz) dialysecentrum. Dit onderzoek bepaalt de implementeerbaarheid van ID.alistic binnen het dialysecentrum door

  3. Ekspert : mobiil-ID kasutamine valimistel turvariske ei tekita / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    E-valimiste projektijuhi Taavi Martensi väitel pole põhjust kahelda mobiil-ID turvalisuses. Valimiskomisjoni esimehe Heiki Sibula meelest peaks m-ID kaarte välja andma kodakondsus- ja migratsiooniamet

  4. 78 FR 773 - Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS...

    Science.gov (United States)

    2013-01-04

    ... Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial... Assistance (TAA) applicable to workers and former workers of Hartford Financial Services Group, Inc., Commercial/ Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford...

  5. India-Based Neutrino Observatory (INO)

    Indian Academy of Sciences (India)

    India-Based Neutrino Observatory (INO) · Atmospheric neutrinos – India connection · INO Collaboration · INO Project components · ICAL: The physics goals · Slide 6 · Slide 7 · INO site : Bodi West Hills · Underground Laboratory Layout · Status of activities at INO Site · Slide 11 · Slide 12 · INO-ICAL Detector · ICAL factsheet.

  6. Asteroids Observed from GMARS and Santana Observatories

    Science.gov (United States)

    Stephens, Robert D.

    2009-01-01

    Lightcurve period and amplitude results from Santana and GMARS Observatories are reported for 2008 June to September: 1472 Muonio, 8.706 ± 0.002 h and 0.50 mag; 2845 Franklinken, 114 ± 1 h and 0.8 mag; and 4533 Orth (> 24 hours).

  7. Reengineering observatory operations for the time domain

    Science.gov (United States)

    Seaman, Robert L.; Vestrand, W. T.; Hessman, Frederic V.

    2014-07-01

    Observatories are complex scientific and technical institutions serving diverse users and purposes. Their telescopes, instruments, software, and human resources engage in interwoven workflows over a broad range of timescales. These workflows have been tuned to be responsive to concepts of observatory operations that were applicable when various assets were commissioned, years or decades in the past. The astronomical community is entering an era of rapid change increasingly characterized by large time domain surveys, robotic telescopes and automated infrastructures, and - most significantly - of operating modes and scientific consortia that span our individual facilities, joining them into complex network entities. Observatories must adapt and numerous initiatives are in progress that focus on redesigning individual components out of the astronomical toolkit. New instrumentation is both more capable and more complex than ever, and even simple instruments may have powerful observation scripting capabilities. Remote and queue observing modes are now widespread. Data archives are becoming ubiquitous. Virtual observatory standards and protocols and astroinformatics data-mining techniques layered on these are areas of active development. Indeed, new large-aperture ground-based telescopes may be as expensive as space missions and have similarly formal project management processes and large data management requirements. This piecewise approach is not enough. Whatever challenges of funding or politics facing the national and international astronomical communities it will be more efficient - scientifically as well as in the usual figures of merit of cost, schedule, performance, and risks - to explicitly address the systems engineering of the astronomical community as a whole.

  8. Education and public engagement in observatory operations

    Science.gov (United States)

    Gabor, Pavel; Mayo, Louis; Zaritsky, Dennis

    2016-07-01

    Education and public engagement (EPE) is an essential part of astronomy's mission. New technologies, remote observing and robotic facilities are opening new possibilities for EPE. A number of projects (e.g., Telescopes In Education, MicroObservatory, Goldstone Apple Valley Radio Telescope and UNC's Skynet) have developed new infrastructure, a number of observatories (e.g., University of Arizona's "full-engagement initiative" towards its astronomy majors, Vatican Observatory's collaboration with high-schools) have dedicated their resources to practical instruction and EPE. Some of the facilities are purpose built, others are legacy telescopes upgraded for remote or automated observing. Networking among institutions is most beneficial for EPE, and its implementation ranges from informal agreements between colleagues to advanced software packages with web interfaces. The deliverables range from reduced data to time and hands-on instruction while operating a telescope. EPE represents a set of tasks and challenges which is distinct from research applications of the new astronomical facilities and operation modes. In this paper we examine the experience with several EPE projects, and some lessons and challenges for observatory operation.

  9. MMS Observatory TV Results Contamination Summary

    Science.gov (United States)

    Rosecrans, Glenn; Brieda, Lubos; Errigo, Therese

    2014-01-01

    The Magnetospheric Multiscale (MMS) mission is a constellation of 4 observatories designed to investigate the fundamental plasma physics of reconnection in the Earth's magnetosphere. The various instrument suites measure electric and magnetic fields, energetic particles, and plasma composition. Each spacecraft has undergone extensive environmental testing to prepare it for its minimum 2 year mission. In this paper, we report on the extensive thermal vacuum testing campaign. The testing was performed at the Naval Research Laboratory utilizing the "Big Blue" vacuum chamber. A total of ten thermal vacuum tests were performed, including two chamber certifications, three dry runs, and five tests of the individual MMS observatories. During the test, the observatories were enclosed in a thermal enclosure known as the "hamster cage". The enclosure allowed for a detailed thermal control of various observatory zone, but at the same time, imposed additional contamination and system performance requirements. The environment inside the enclosure and the vacuum chamber was actively monitored by several QCMs, RGA, and up to 18 ion gauges. Each spacecraft underwent a bakeout phase, which was followed by 4 thermal cycles. Unique aspects of the TV campaign included slow pump downs with a partial represses, thruster firings, Helium identification, and monitoring pressure spikes with ion gauges. Selected data from these TV tests is presented along with lessons learned.

  10. Reverberation Mapping Results from MDM Observatory

    DEFF Research Database (Denmark)

    Denney, Kelly D.; Peterson, B. M.; Pogge, R. W.

    2009-01-01

    We present results from a multi-month reverberation mapping campaign undertaken primarily at MDM Observatory with supporting observations from around the world. We measure broad line region (BLR) radii and black hole masses for six objects. A velocity-resolved analysis of the H_beta response show...

  11. Robotic Autonomous Observatories: A Historical Perspective

    Directory of Open Access Journals (Sweden)

    Alberto Javier Castro-Tirado

    2010-01-01

    Full Text Available This paper presents a historical introduction to the field of Robotic Astronomy, from the point of view of a scientist working in this field for more than a decade. The author discusses the basic definitions, the differing telescope control operating systems, observatory managers, as well as a few current scientific applications.

  12. Geomagnetic secular variation at the African observatories

    International Nuclear Information System (INIS)

    Haile, T.

    2002-10-01

    Geomagnetic data from ten observatories in the African continent with time series data length of more than three decades have been analysed. All-day annual mean values of the D, H and Z components were used to study secular variations in the African region. The residuals in D, H and Z components obtained after removing polynomial fits have been examined in relation to the sunspot cycle. The occurrence of the 1969-1970 worldwide geomagnetic impulse in each observatory is studied. It is found that the secular variation in the field can be represented for most of the observatories with polynomials of second or third degree. Departures from these trends are observed over the Southern African region where strong local magnetic anomalies have been observed. The residuals in the geomagnetic field components have been shown to exhibit parallelism with the periods corresponding to double solar cycle for some of the stations. A clear latitudinal distribution in the geomagnetic component that exhibits the 1969-70 jerk is shown. The jerk appears in the plots of the first differences in H for the southern most observatories of Hermanus, Hartebeesthoek, and Tsuemb, while the Z plots show the jerk for near equatorial and equatorial stations of Antananarivo, Luanda Belas, Bangui and Addis Ababa. There is some indication for this jerk in the first difference plots of D for the northern stations of M'Bour and Tamanrasset. The plots of D rather strongly suggest the presence of a jerk around 1980 at most of the stations. (author)

  13. Astronomical Virtual Observatories Through International Collaboration

    Directory of Open Access Journals (Sweden)

    Masatoshi Ohishi

    2010-03-01

    Full Text Available Astronomical Virtual Observatories (VOs are emerging research environment for astronomy, and 16 countries and a region have funded to develop their VOs based on international standard protocols for interoperability. The 16 funded VO projects have established the International Virtual Observatory Alliance (http://www.ivoa.net/ to develop the standard interoperable interfaces such as registry (meta data, data access, query languages, output format (VOTable, data model, application interface, and so on. The IVOA members have constructed each VO environment through the IVOA interfaces. National Astronomical Observatory of Japan (NAOJ started its VO project (Japanese Virtual Observatory - JVO in 2002, and developed its VO system. We have succeeded to interoperate the latest JVO system with other VOs in the USA and Europe since December 2004. Observed data by the Subaru telescope, satellite data taken by the JAXA/ISAS, etc. are connected to the JVO system. Successful interoperation of the JVO system with other VOs means that astronomers in the world will be able to utilize top-level data obtained by these telescopes from anywhere in the world at anytime. System design of the JVO system, experiences during our development including problems of current standard protocols defined in the IVOA, and proposals to resolve these problems in the near future are described.

  14. Lights go out at city observatory

    CERN Multimedia

    Armstrong, R

    2003-01-01

    Edinburgh's Royal Observatory is to close its doors to the public due to dwindling visitor numbers. The visitor centre will remain open to the general public for planned lectures and night-time observing sessions, but will cease to be open on a daily basis from next month (1/2 page).

  15. Radioecological Observatories - Breeding Grounds for Innovative Research

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, Martin; Urso, Laura; Wichterey, Karin; Willrodt, Christine [Bundesamt fuer Strahlenschutz - BfS, Willy-Brandt-Strasse 5, 38226 Salzgitter (Germany); Beresford, Nicholas A.; Howard, Brenda [NERC Centre for Ecology and Hydrology - CEH, Lancaster Environment Centre, Library Av., Bailrigg, Lancaster, LA1 4AP (United Kingdom); Bradshaw, Clare; Stark, Karolina [Stockholms Universitet - SU, Universitetsvaegen 10, SE-10691 Stockholm (Sweden); Dowdall, Mark; Liland, Astrid [Norwegian Radiation Protection Authority - NRPA, P.O. Box 55, NO-1332 Oesteraas (Norway); Eyrolle- Boyer, Frederique; Guillevic, Jerome; Hinton, Thomas [Institut de Radioprotection et de Surete Nucleaire - IRSN, 31, Avenue de la Division Leclerc, 92260 Fontenay-aux-Roses (France); Gashchak, Sergey [Chornobyl Center for Nuclear Safety, Radioactive Waste and Radioecology - Chornobyl Center, 77th Gvardiiska Dyviiya str.7/1, 07100 Slavutych (Ukraine); Hutri, Kaisa-Leena; Ikaeheimonen, Tarja; Muikku, Maarit; Outola, Iisa [Radiation and Nuclear Safety Authority - STUK, P.O. Box 14, 00881 Helsinki (Finland); Michalik, Boguslaw [Glowny Instytut Gornictwa - GIG, Plac Gwarkow 1, 40-166 Katowice (Poland); Mora, Juan Carlos; Real, Almudena; Robles, Beatriz [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas - CIEMAT, Avenida complutense, 40, 28040 Madrid (Spain); Oughton, Deborah; Salbu, Brit [Norwegian University of Life Sciences - NMBU, P.O. Box 5003, NO-1432 Aas (Norway); Sweeck, Lieve [Studiecentrum voor Kernenergie/Centre d' Etude de l' Energie Nucleaire (SCK.CEN), Avenue Herrmann- Debroux 40, BE-1160 Brussels (Belgium); Yoschenko, Vasyl [National University of Life and Environmental Sciences of Ukraine (NUBiP of Ukraine), Herojiv Obrony st., 15, Kyiv-03041 (Ukraine)

    2014-07-01

    Within the EC-funded (FP7) Network of Excellence STAR (Strategy for Allied Radioecology, www.star-radioecology.org) the concept of Radioecological Observatories is currently being implemented on a European level for the first time. Radioecological Observatories are radioactively (and chemically) contaminated field sites that will provide a focus for joint long-term radioecological research. The benefit of this innovative approach is to create synergistic research collaborations by sharing expertise, ideas, data and resources. Research at the Radioecological Observatories will primarily focus on radioecological challenges outlined in the Strategic Research Agenda (SRA). Mechanisms to use these sites will be established under the EC-funded project COMET (Coordination and Implementation of a Pan-European Instrument for Radioecology, www.comet-radioecology.org). The European Radioecological Observatory sites were selected using a structured, progressive approach that was transparent, consistent and objective. A first screening of potential candidate sites was conducted based on the following exclusion criteria: long-term perspective for shared field work and suitability for addressing the radioecological challenges of the SRA. The proposed sites included former uranium mining and milling sites in France and Germany, the Chernobyl Exclusion Zone (CEZ) in Ukraine/Belarus and the Upper Silesian Coal Basin (USCB) in Poland. All candidate sites were prioritized based on evaluation criteria which comprised scientific issues, available infrastructure, administrative/legal constraints and financial considerations. Multi-criteria decision analysis, group discussions and recommendations provided by external experts were combined to obtain a preference order among the suggested sites. Using this approach, the Upper Silesian Coal Basin (USCB) in Poland and the Chernobyl Exclusion Zone (CEZ) were selected as Radioecological Observatories. The two sites have similar multi

  16. People with ID as interviewers and co-researchers: experiences and reflection.

    NARCIS (Netherlands)

    Lieshout, H. van

    2012-01-01

    Aim: To share the experience of working with people with intellectual disabilities (ID) as interviewers in a qualitative study about community participation of people with ID. We reflect on two perspectives: the interviewers and the researchers. Method: Eighteen people with ID were interviewed by

  17. 78 FR 8596 - Hartford Financial Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS...

    Science.gov (United States)

    2013-02-06

    ... Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial... workers and former workers of Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford, Connecticut (The Hartford-IDS...

  18. Picture This: How to Establish an Effective School ID Card Program

    Science.gov (United States)

    Finkelstein, David

    2013-01-01

    Most school districts do not have an ID card policy that everyone knows and follows, yet. many school districts are implementing ID card programs to address concerns about safety, efficiency, and convenience. A well-thought-out ID card program leads to greater security and smoother operations throughout the school and should thus be a priority.…

  19. Development of Armenian-Georgian Virtual Observatory

    Science.gov (United States)

    Mickaelian, Areg; Kochiashvili, Nino; Astsatryan, Hrach; Harutyunian, Haik; Magakyan, Tigran; Chargeishvili, Ketevan; Natsvlishvili, Rezo; Kukhianidze, Vasil; Ramishvili, Giorgi; Sargsyan, Lusine; Sinamyan, Parandzem; Kochiashvili, Ia; Mikayelyan, Gor

    2009-10-01

    The Armenian-Georgian Virtual Observatory (ArGVO) project is the first initiative in the world to create a regional VO infrastructure based on national VO projects and regional Grid. The Byurakan and Abastumani Astrophysical Observatories are scientific partners since 1946, after establishment of the Byurakan observatory . The Armenian VO project (ArVO) is being developed since 2005 and is a part of the International Virtual Observatory Alliance (IVOA). It is based on the Digitized First Byurakan Survey (DFBS, the digitized version of famous Markarian survey) and other Armenian archival data. Similarly, the Georgian VO will be created to serve as a research environment to utilize the digitized Georgian plate archives. Therefore, one of the main goals for creation of the regional VO is the digitization of large amounts of plates preserved at the plate stacks of these two observatories. The total amount of plates is more than 100,000 units. Observational programs of high importance have been selected and some 3000 plates will be digitized during the next two years; the priority is being defined by the usefulness of the material for future science projects, like search for new objects, optical identifications of radio, IR, and X-ray sources, study of variability and proper motions, etc. Having the digitized material in VO standards, a VO database through the regional Grid infrastructure will be active. This partnership is being carried out in the framework of the ISTC project A-1606 "Development of Armenian-Georgian Grid Infrastructure and Applications in the Fields of High Energy Physics, Astrophysics and Quantum Physics".

  20. Applying risk management strategies to strengthen an IDS's investment policy.

    Science.gov (United States)

    Fine, R P

    1998-11-01

    The increased financial risk that not-for-profit integrated delivery systems have assumed to function under managed care has required them to become increasingly reliant on income and gains from their investment portfolios. This reliance underscores the need for these organizations to take steps to effectively manage their investment risk. Not-for-profit IDSs should establish a systematic approach to investment risk management that is based on maintaining a sound fiduciary infrastructure and having a clear understanding of risk exposures, the most important of which are policy and market risk. Applying reasonable and common-sense risk management strategies to investment policy will enhance an IDS's overall financial and competitive strength.

  1. An ID-based Blind Signature Scheme from Bilinear Pairings

    OpenAIRE

    B.Umaprasada Rao; K.A.Ajmath

    2010-01-01

    Blind signatures, introduced by Chaum, allow a user to obtain a signature on a message without revealing any thing about the message to the signer. Blind signatures play on important role in plenty of applications such as e-voting, e-cash system where anonymity is of great concern. Identity based(ID-based) public key cryptography can be a good alternative for certified based public key setting, especially when efficient key management and moderate security are required. In this paper, we prop...

  2. RFID and Auto-ID in planning and logistics

    CERN Document Server

    Jones, Erick C

    2011-01-01

    As RFID technology is becoming increasingly popular, the need has arisen to address the challenges and approaches to successful implementation. RFID and Auto-ID in Planning and Logistics: A Practical Guide for Military UID Applications presents the concepts for students, military personnel and contractors, and corporate managers to learn about RFID and other automatic information capture technologies, and their integration into planning and logistics functions. The text includes comparisons of RFID with technologies such as bar codes, satellite tags, and global positioning systems and provides

  3. Labelling IDS clusters by means of the silhouette index

    OpenAIRE

    Petrovic, Slovodan; Álvarez, Gonzalo; Orfila, Agustín; Carbó, Javier

    2006-01-01

    Proceeding of: IX Reunión Española sobre Criptología y Seguridad de la Información. Barcelona, 2006 One of the most difficult problems in the design of an anomaly based intrusion detection system (IDS) that uses clustering is that of labelling the ob- tained clusters, i.e. determining which of them correspond to ”good” behaviour on the network/host and which to ”bad” behaviour. In this paper, a new clusters’ labelling strategy, which makes use of the Silhouette clustering quality index is ...

  4. Predicting Students’ Performance using Modified ID3 Algorithm

    OpenAIRE

    Ramanathan L; Saksham Dhanda; Suresh Kumar D

    2013-01-01

    The ability to predict performance of students is very crucial in our present education system. We can use data mining concepts for this purpose. ID3 algorithm is one of the famous algorithms present today to generate decision trees. But this algorithm has a shortcoming that it is inclined to attributes with many values. So , this research aims to overcome this shortcoming of the algorithm by using gain ratio(instead of information gain) as well as by giving weights to each attribute at every...

  5. O evangelho segundo o McDonald's: estudo sobre o processo de produção da fast-food

    OpenAIRE

    Alves, Carmen Lucia Rodrigues

    2006-01-01

    Este estudo aborda o processo de produção da cadeia de fast-food McDonald s, resgatando a forma de produzir seus alimentos, a tecnologia investida, as definições sobre cor, aroma, gosto; as relações de trabalho, desde a estrutura funcional dos trabalhadores, a seleção dos funcionários e o treinamento para cumprir todas as funções que concretizam o processo produtivo. Enfoca, também, através da análise da propaganda de seus produtos, a ideologia que veicula, particularmente p...

  6. Operations of and Future Plans for the Pierre Auger Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, : J.; Abreu, P.; Aglietta, M.; Aguirre, C.; Ahn, E.J.; Allard, D.; Allekotte, I.; Allen, J.; Alvarez-Muniz, J.; Ambrosio, M.; Anchordoqui, L.

    2009-06-01

    These are presentations to be presented at the 31st International Cosmic Ray Conference, in Lodz, Poland during July 2009. It consists of the following presentations: (1) Performance and operation of the Surface Detectors of the Pierre Auger Observatory; (2) Extension of the Pierre Auger Observatory using high-elevation fluorescence telescopes (HEAT); (3) AMIGA - Auger Muons and Infill for the Ground Array of the Pierre Auger Observatory; (4) Radio detection of Cosmic Rays at the southern Auger Observatory; (5) Hardware Developments for the AMIGA enhancement at the Pierre Auger Observatory; (6) A simulation of the fluorescence detectors of the Pierre Auger Observatory using GEANT 4; (7) Education and Public Outreach at the Pierre Auger Observatory; (8) BATATA: A device to characterize the punch-through observed in underground muon detectors and to operate as a prototype for AMIGA; and (9) Progress with the Northern Part of the Pierre Auger Observatory.

  7. The Paris Observatory has 350 years

    Science.gov (United States)

    Lequeux, James

    2017-01-01

    The Paris Observatory is the oldest astronomical observatory that has worked without interruption since its foundation to the present day. The building due to Claude Perrault is still in existence with few modifications, but of course other buildings have been added all along the centuries for housing new instruments and laboratories. In particular, a large dome has been built on the terrace in 1847, with a 38-cm diameter telescope completed in 1857: both are still visible. The main initial purpose of the Observatory was to determine longitudes. This was achieved by Jean-Dominique Cassini using the eclipses of the satellites of Jupiter: a much better map of France was the produced using this method, which unfortunately does not work at sea. Incidentally, the observation of these eclipses led to the discovery in 1676 of the finite velocity of light by Cassini and Rømer. Cassini also discovered the differential rotation of Jupiter and four satellites of Saturn. Then, geodesy was to be the main activity of the Observatory for more than a century, culminating in the famous Cassini map of France completed around 1790. During the first half of the 19th century, under François Arago, the Observatory was at the centre of French physics, which then developed very rapidly. Arago initiated astrophysics in 1810 by showing that the Sun and stars are made of incandescent gas. In 1854, the new director, Urbain Le Verrier, put emphasis on astrometry and celestial mechanics, discovering in particular the anomalous advance of the perihelion of Mercury, which was later to be a proof of General Relativity. In 1858, Leon Foucault built the first modern reflecting telescopes with their silvered glass mirror. Le Verrier created on his side modern meteorology, including some primitive forecasts. The following period was not so bright, due to the enormous project of the Carte du Ciel, which took much of the forces of the Observatory for half a century with little scientific return. In

  8. Brazil to Join the European Southern Observatory

    Science.gov (United States)

    2010-12-01

    The Federative Republic of Brazil has yesterday signed the formal accession agreement paving the way for it to become a Member State of the European Southern Observatory (ESO). Following government ratification Brazil will become the fifteenth Member State and the first from outside Europe. On 29 December 2010, at a ceremony in Brasilia, the Brazilian Minister of Science and Technology, Sergio Machado Rezende and the ESO Director General, Tim de Zeeuw signed the formal accession agreement aiming to make Brazil a Member State of the European Southern Observatory. Brazil will become the fifteen Member State and the first from outside Europe. Since the agreement means accession to an international convention, the agreement must now be submitted to the Brazilian Parliament for ratification [1]. The signing of the agreement followed the unanimous approval by the ESO Council during an extraordinary meeting on 21 December 2010. "Joining ESO will give new impetus to the development of science, technology and innovation in Brazil as part of the considerable efforts our government is making to keep the country advancing in these strategic areas," says Rezende. The European Southern Observatory has a long history of successful involvement with South America, ever since Chile was selected as the best site for its observatories in 1963. Until now, however, no non-European country has joined ESO as a Member State. "The membership of Brazil will give the vibrant Brazilian astronomical community full access to the most productive observatory in the world and open up opportunities for Brazilian high-tech industry to contribute to the European Extremely Large Telescope project. It will also bring new resources and skills to the organisation at the right time for them to make a major contribution to this exciting project," adds ESO Director General, Tim de Zeeuw. The European Extremely Large Telescope (E-ELT) telescope design phase was recently completed and a major review was

  9. Revocable ID-Based Signature with Short Size over Lattices

    Directory of Open Access Journals (Sweden)

    Ying-Hao Hung

    2017-01-01

    Full Text Available In the past, many ID-based signature (IBS schemes based on the integer factorization or discrete logarithm problems were proposed. With the progress on the development of quantum technology, IBS schemes mentioned above would become vulnerable. Recently, several IBS schemes over lattices were proposed to be secure against attacks in the quantum era. As conventional public-key settings, ID-based public-key settings have to offer a revocation mechanism to revoke misbehaving or malicious users. However, in the past, little work focuses on the revocation problem in the IBS schemes over lattices. In this article, we propose a new revocable IBS (RIBS scheme with short size over lattices. Based on the short integer solution (SIS assumption, we prove that the proposed RIBS scheme provides existential unforgeability against adaptive chosen-message attacks. As compared to the existing IBS schemes over lattices, our RIBS scheme has better performance in terms of signature size, signing key size, and the revocation mechanism with public channels.

  10. Secure OpenID Authentication Model by Using Trusted Computing

    Directory of Open Access Journals (Sweden)

    E. Ghazizadeh

    2014-01-01

    Full Text Available The growth of Internet online services has been very quick in recent years. Each online service requires Internet users to create a new account to use the service. The problem can be seen when each user usually needs more than one service and, consequently, has numerous accounts. These numerous accounts have to be managed in a secure and simple way to be protected against identity theft. Single sign-on (SSO and OpenID have been used to decrease the complexity of managing numerous accounts required in the Internet identity environment. Trusted Platform Module (TPM and Trust Multitenancy are great trusted computing-based technologies to solve security concerns in the Internet identity environment. Since trust is one of the pillars of security in the cloud, this paper analyzes the existing cloud identity techniques in order to investigate their strengths and weaknesses. This paper proposes a model in which One Time Password (OTP, TPM, and OpenID are used to provide a solution against phishing as a common identity theft in cloud environment.

  11. Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.

    Directory of Open Access Journals (Sweden)

    April S Chan

    2009-11-01

    Full Text Available The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells naturally suggests that they interact with one another, but these interactions are just beginning to be characterized.An Id1(-/- mouse model was used to assess the role of Id1 in the bone marrow microenvironment. Micro-computed tomography and fracture tests showed that Id1(-/- mice have reduced bone mass and increased bone fragility, consistent with an osteoporotic phenotype. Osteoclastogenesis and pit formation assays revealed that loss of Id1 increased osteoclast differentiation and resorption activity, both in vivo and in vitro, suggesting a cell autonomous role for Id1 as a negative regulator of osteoclast differentiation. Examination by flow cytometry of the hematopoietic compartment of Id1(-/- mice showed an increase in myeloid differentiation. Additionally, we found increased expression of osteoclast genes, TRAP, Oscar, and CTSK in the Id1(-/- bone marrow microenvironment. Lastly, transplantation of wild-type bone marrow into Id1(-/- mice repressed TRAP, Oscar, and CTSK expression and activity and rescued the hematopoietic and bone phenotype in these mice.In conclusion, we demonstrate an osteoporotic phenotype in Id1(-/- mice and a mechanism for Id1 transcriptional control of osteoclast-associated genes. Our results identify Id1 as a principal player responsible for the dynamic cross-talk between bone and bone marrow hematopoietic cells.

  12. The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site

    DEFF Research Database (Denmark)

    Babakhanyan, Anna; Leke, Rose G F; Salanti, Ali

    2014-01-01

    In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women natura...

  13. Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-Occurring ASD and ID

    Science.gov (United States)

    Schieve, Laura A.; Clayton, Heather B.; Durkin, Maureen S.; Wingate, Martha S.; Drews-Botsch, Carolyn

    2015-01-01

    While studies report associations between perinatal outcomes and both autism spectrum disorder (ASD) and intellectual disability (ID), there has been little study of ASD with versus without co-occurring ID. We compared perinatal risk factors among 7547 children in the 2006-2010 Autism and Developmental Disability Monitoring Network classified as…

  14. Data standards for the international virtual observatory

    Directory of Open Access Journals (Sweden)

    R J Hanisch

    2006-11-01

    Full Text Available A primary goal of the International Virtual Observatory Alliance, which brings together Virtual Observatory Projects from 16 national and international development projects, is to develop, evaluate, test, and agree upon standards for astronomical data formatting, data discovery, and data delivery. In the three years that the IVOA has been in existence, substantial progress has been made on standards for tabular data, imaging data, spectroscopic data, and large-scale databases and on managing the metadata that describe data collections and data access services. In this paper, I describe how the IVOA operates and give my views as to why such a broadly based international collaboration has been able to make such rapid progress.

  15. Beyond the Observatory: Reflections on the Centennial

    Science.gov (United States)

    Devorkin, D. H.

    1999-05-01

    One of the many unexpected side-benefits of acting as editor of the AAS centennial volume was the chance to take a fresh look at some of the personalities who helped to shape the American Astronomical Society. A common characteristic of these people was their energy, compassion and drive to go "Beyond the Observatory," to borrow a phrase from Harlow Shapley. But what did going `beyond the observatory' mean to Shapley, or to the others who shaped and maintained the Society in its first one hundred years of life? Just as the discipline of astronomy has changed in profound ways in the past century, so has the American Astronomical Society changed, along with the people who have been its leaders and its sustainers and the culture that has fostered it. The Centennial meeting of the Society offers a chance to reflect on the people who have given American astronomy its sense of community identity.

  16. The STELLA Robotic Observatory on Tenerife

    Directory of Open Access Journals (Sweden)

    Klaus G. Strassmeier

    2010-01-01

    Full Text Available The Astrophysical Institute Potsdam (AIP and the Instituto de Astrofísica de Canarias (IAC inaugurated the robotic telescopes STELLA-I and STELLA-II (STELLar Activity on Tenerife on May 18, 2006. The observatory is located on the Izaña ridge at an elevation of 2400 m near the German Vacuum Tower Telescope. STELLA consists of two 1.2 m alt-az telescopes. One telescope fiber feeds a bench-mounted high-resolution echelle spectrograph while the other telescope feeds a wide-field imaging photometer. Both scopes work autonomously by means of artificial intelligence. Not only that the telescopes are automated, but the entire observatory operates like a robot, and does not require any human presence on site.

  17. High Energy Astronomy Observatory (HEAO)-2

    Science.gov (United States)

    1982-01-01

    This artist's concept depicts the High Energy Astronomy Observatory (HEAO)-2 in orbit. The HEAO-2, the first imaging and largest x-ray telescope built to date, was capable of producing actual photographs of x-ray objects. Shortly after launch, the HEAO-2 was nicknamed the Einstein Observatory by its scientific experimenters in honor of the centernial of the birth of Albert Einstein, whose concepts of relativity and gravitation have influenced much of modern astrophysics, particularly x-ray astronomy. The HEAO-2, designed and developed by TRW, Inc. under the project management of the Marshall Space Flight Center, was launched aboard an Atlas/Centaur launch vehicle on November 13, 1978. The HEAO-2 was originally identified as HEAO-B but the designation was changed once the spacecraft achieved orbit.

  18. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    International Nuclear Information System (INIS)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep

    2016-01-01

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  19. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep, E-mail: jchaudhary@cau.edu

    2016-09-09

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  20. The value of conventional high-field MRI in MS in the light of the McDonald criteria: a literature review.

    Science.gov (United States)

    Lunde Larsen, L S; Larsson, H B W; Frederiksen, J L

    2010-09-01

    The diagnosis of MS is based on the revised McDonald criteria and is multidisciplinary. Both clinical and paraclinical measures are included. High-field magnetic resonance imaging (MRI) is becoming increasingly available and it is therefore necessary to clarify possible advantages of high-field MRI in MS. The aim of this paper was to review MRI studies in MS where a direct comparison of MRI at high field with MRI at 1-1.5 tesla (T) had been performed. The studies evaluated were found by searching Pubmed with relevant terms including MeSH terms. The reviewed studies all found the conspicuity of lesions to be better at high field. Of the seven studies, six found more and bigger lesions at high-field MRI. In the present paper, the relevant MRI sequences are evaluated in detail. The detection of more lesions at high-field strength did not seem to lead to earlier diagnosis of clinically definite multiple sclerosis. Further larger studies of patients with clinically isolated syndromes are needed to settle the question of a diagnostic consequence of high-field imaging in MS. We suggest that the next revision of the McDonald diagnostic criteria include a recommendation of field strength.

  1. Clinically Isolated Syndrome According to McDonald 2010: Intrathecal IgG Synthesis Still Predictive for Conversion to Multiple Sclerosis

    Directory of Open Access Journals (Sweden)

    Philipp Schwenkenbecher

    2017-09-01

    Full Text Available While the revised McDonald criteria of 2010 allow for the diagnosis of multiple sclerosis (MS in an earlier stage, there is still a need to identify the risk factors for conversion to MS in patients with clinically isolated syndrome (CIS. Since the latest McDonald criteria were established, the prognostic role of cerebrospinal fluid (CSF and visual evoked potentials (VEP in CIS patients is still poorly defined. We conducted a monocentric investigation including patients with CIS in the time from 2010 to 2015. Follow-ups of 120 patients revealed that 42% converted to MS. CIS patients with positive oligoclonal bands (OCB were more than twice as likely to convert to MS as OCB negative patients (hazard ratio = 2.6. The probability to develop MS was even higher when a quantitative intrathecal IgG synthesis was detected (hazard ratio = 3.8. In patients with OCB, VEP did not add further information concerning the conversion rate to MS. In patients with optic neuritis and negative OCB, a significantly higher rate converted to MS when VEP were delayed. In conclusion, the detection of an intrathecal IgG synthesis increases the conversion probability to MS. Pathological VEP can help to predict the conversion rate to MS in patients with optic neuritis without an intrathecal IgG synthesis.

  2. Radikal konservativ idédebat og højreautoritær fascination i Danmark, ca. 1928-1940

    DEFF Research Database (Denmark)

    Holm, Adam

    1999-01-01

    Historie, Højreradikalisme, Konservatisme, Fascisme, Mellemkrigstid, Idéhistorie, Intellektuelle......Historie, Højreradikalisme, Konservatisme, Fascisme, Mellemkrigstid, Idéhistorie, Intellektuelle...

  3. Observatory Magnetometer In-Situ Calibration

    Directory of Open Access Journals (Sweden)

    A Marusenkov

    2011-07-01

    Full Text Available An experimental validation of the in-situ calibration procedure, which allows estimating parameters of observatory magnetometers (scale factors, sensor misalignment without its operation interruption, is presented. In order to control the validity of the procedure, the records provided by two magnetometers calibrated independently in a coil system have been processed. The in-situ estimations of the parameters are in very good agreement with the values provided by the coil system calibration.

  4. From AISR to the Virtual Observatory

    Science.gov (United States)

    Szalay, Alexander S.

    2014-01-01

    The talk will provide a retrospective on important results enabled by the NASA AISR program. The program had a unique approach to funding research at the intersection of astrophysics, applied computer science and statistics. It had an interdisciplinary angle, encouraged high risk, high return projects. Without this program the Virtual Observatory would have never been started. During its existence the program has funded some of the most innovative applied computer science projects in astrophysics.

  5. Utilizing Internet Technologies in Observatory Control Systems

    Science.gov (United States)

    Cording, Dean

    2002-12-01

    The 'Internet boom' of the past few years has spurred the development of a number of technologies to provide services such as secure communications, reliable messaging, information publishing and application distribution for commercial applications. Over the same period, a new generation of computer languages have also developed to provide object oriented design and development, improved reliability, and cross platform compatibility. Whilst the business models of the 'dot.com' era proved to be largely unviable, the technologies that they were based upon have survived and have matured to the point were they can now be utilized to build secure, robust and complete observatory control control systems. This paper will describe how Electro Optic Systems has utilized these technologies in the development of its third generation Robotic Observatory Control System (ROCS). ROCS provides an extremely flexible configuration capability within a control system structure to provide truly autonomous robotic observatory operation including observation scheduling. ROCS was built using Internet technologies such as Java, Java Messaging Service (JMS), Lightweight Directory Access Protocol (LDAP), Secure Sockets Layer (SSL), eXtendible Markup Language (XML), Hypertext Transport Protocol (HTTP) and Java WebStart. ROCS was designed to be capable of controlling all aspects of an observatory and be able to be reconfigured to handle changing equipment configurations or user requirements without the need for an expert computer programmer. ROCS consists of many small components, each designed to perform a specific task, with the configuration of the system specified using a simple meta language. The use of small components facilitates testing and makes it possible to prove that the system is correct.

  6. The architecture of LAMOST observatory control system

    International Nuclear Information System (INIS)

    Wang Jian; Jin Ge; Yu Xiaoqi; Wan Changsheng; Hao Likai; Li Xihua

    2005-01-01

    The design of architecture is the one of the most important part in development of Observatory Control System (OCS) for LAMOST. Based on the complexity of LAMOST, long time of development for LAMOST and long life-cycle of OCS system, referring many kinds of architecture pattern, the architecture of OCS is established which is a component-based layered system using many patterns such as the MVC and proxy. (authors)

  7. Technology Development for a Neutrino Astrophysical Observatory

    International Nuclear Information System (INIS)

    Chaloupka, V.; Cole, T.; Crawford, H.J.; He, Y.D.; Jackson, S.; Kleinfelder, S.; Lai, K.W.; Learned, J.; Ling, J.; Liu, D.; Lowder, D.; Moorhead, M.; Morookian, J.M.; Nygren, D.R.; Price, P.B.; Richards, A.; Shapiro, G.; Shen, B.; Smoot, George F.; Stokstad, R.G.; VanDalen, G.; Wilkes, J.; Wright, F.; Young, K.

    1996-01-01

    We propose a set of technology developments relevant to the design of an optimized Cerenkov detector for the study of neutrino interactions of astrophysical interest. Emphasis is placed on signal processing innovations that enhance significantly the quality of primary data. These technical advances, combined with field experience from a follow-on test deployment, are intended to provide a basis for the engineering design for a kilometer-scale Neutrino Astrophysical Observatory

  8. A robotic observatory in the city

    Science.gov (United States)

    Ruch, Gerald T.; Johnston, Martin E.

    2012-05-01

    The University of St. Thomas (UST) Observatory is an educational facility integrated into UST's undergraduate curriculum as well as the curriculum of several local schools. Three characteristics combine to make the observatory unique. First, the telescope is tied directly to the support structure of a four-story parking ramp instead of an isolated pier. Second, the facility can be operated remotely over an Internet connection and is capable of performing observations without a human operator. Third, the facility is located on campus in the heart of a metropolitan area where light pollution is severe. Our tests indicate that, despite the lack of an isolated pier, vibrations from the ramp do not degrade the image quality at the telescope. The remote capability facilitates long and frequent observing sessions and allows others to use the facility without traveling to UST. Even with the high background due to city lights, the sensitivity and photometric accuracy of the system are sufficient to fulfill our pedagogical goals and to perform a variety of scientific investigations. In this paper, we outline our educational mission, provide a detailed description of the observatory, and discuss its performance characteristics.

  9. LAGO: The Latin American giant observatory

    Science.gov (United States)

    Sidelnik, Iván; Asorey, Hernán; LAGO Collaboration

    2017-12-01

    The Latin American Giant Observatory (LAGO) is an extended cosmic ray observatory composed of a network of water-Cherenkov detectors (WCD) spanning over different sites located at significantly different altitudes (from sea level up to more than 5000 m a.s.l.) and latitudes across Latin America, covering a wide range of geomagnetic rigidity cut-offs and atmospheric absorption/reaction levels. The LAGO WCD is simple and robust, and incorporates several integrated devices to allow time synchronization, autonomous operation, on board data analysis, as well as remote control and automated data transfer. This detection network is designed to make detailed measurements of the temporal evolution of the radiation flux coming from outer space at ground level. LAGO is mainly oriented to perform basic research in three areas: high energy phenomena, space weather and atmospheric radiation at ground level. It is an observatory designed, built and operated by the LAGO Collaboration, a non-centralized collaborative union of more than 30 institutions from ten countries. In this paper we describe the scientific and academic goals of the LAGO project - illustrating its present status with some recent results - and outline its future perspectives.

  10. The Lowell Observatory Predoctoral Fellowship Program

    Science.gov (United States)

    Prato, Lisa A.; Shkolnik, E.

    2014-01-01

    Lowell Observatory is pleased to solicit applications for our Predoctoral Fellowship Program. Now beginning its seventh year, this program is designed to provide unique research opportunities to graduate students in good standing, currently enrolled at Ph.D. granting institutions. Lowell staff research spans a wide range of topics, from astronomical instrumentation, to icy bodies in our solar system, exoplanet science, stellar populations, star formation, and dwarf galaxies. The Observatory's new 4.3 meter Discovery Channel Telescope has successfully begun science operations and we anticipate the commissioning of several new instruments in 2014, making this a particularly exciting time to do research at Lowell. Student research is expected to lead to a thesis dissertation appropriate for graduation at the doctoral level at the student's home institution. The Observatory provides competitive compensation and full benefits to student scholars. For more information, see http://www2.lowell.edu/rsch/predoc.php and links therein. Applications for Fall 2014 are due by May 1, 2014.

  11. Recent results from the Compton Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Michelson, P.F.; Hansen, W.W. [Stanford Univ., CA (United States)

    1994-12-01

    The Compton Observatory is an orbiting astronomical observatory for gamma-ray astronomy that covers the energy range from about 30 keV to 30 GeV. The Energetic Gamma Ray Experiment Telescope (EGRET), one of four instruments on-board, is capable of detecting and imaging gamma radiation from cosmic sources in the energy range from approximately 20 MeV to 30 GeV. After about one month of tests and calibration following the April 1991 launch, a 15-month all sky survey was begun. This survey is now complete and the Compton Observatory is well into Phase II of its observing program which includes guest investigator observations. Among the highlights from the all-sky survey discussed in this presentation are the following: detection of five pulsars with emission above 100 MeV; detection of more than 24 active galaxies, the most distant at redshift greater than two; detection of many high latitude, unidentified gamma-ray sources, some showing significant time variability; detection of at least two high energy gamma-ray bursts, with emission in one case extending to at least 1 GeV. EGRET has also detected gamma-ray emission from solar flares up to energies of at least 2 GeV and has observed gamma-rays from the Large Magellanic Cloud.

  12. The brazilian indigenous planetary-observatory

    Science.gov (United States)

    Afonso, G. B.

    2003-08-01

    We have performed observations of the sky alongside with the Indians of all Brazilian regions that made it possible localize many indigenous constellations. Some of these constellations are the same as the other South American Indians and Australian aborigines constellations. The scientific community does not have much of this information, which may be lost in one or two generations. In this work, we present a planetary-observatory that we have made in the Park of Science Newton Freire-Maia of Paraná State, in order to popularize the astronomical knowledge of the Brazilian Indians. The planetary consists, essentially, of a sphere of six meters in diameter and a projection cylinder of indigenous constellations. In this planetary we can identify a lot of constellations that we have gotten from the Brazilian Indians; for instance, the four seasonal constellations: the Tapir (spring), the Old Man (summer), the Deer (autumn) and the Rhea (winter). A two-meter height wooden staff that is posted vertically on the horizontal ground similar to a Gnomon and stones aligned with the cardinal points and the soltices directions constitutes the observatory. A stone circle of ten meters in diameter surrounds the staff and the aligned stones. During the day we observe the Sun apparent motions and at night the indigenous constellations. Due to the great community interest in our work, we are designing an itinerant indigenous planetary-observatory to be used in other cities mainly by indigenous and primary schools teachers.

  13. Forensic validation of the SNPforID 52-plex assay

    DEFF Research Database (Denmark)

    Musgrave-Brown, Esther; Ballard, David; Balogh, Kinga

    2007-01-01

    The advantages of single nucleotide polymorphism (SNP) typing in forensic genetics are well known and include a wider choice of high-throughput typing platforms, lower mutation rates, and improved analysis of degraded samples. However, if SNPs are to become a realistic supplement to current short...... tandem repeat (STR) typing methods, they must be shown to successfully and reliably analyse the challenging samples commonly encountered in casework situations. The European SNPforID consortium, supported by the EU GROWTH programme, has developed a multiplex of 52 SNPs for forensic analysis...... in forensic casework. A total of 40 extracts were used in the study, each of which was sent to two of the five participating laboratories for typing in duplicate or triplicate. Laboratories were instructed to carry out their analyses as if they were dealing with normal casework samples. Results were reported...

  14. Applying Open Researchers and Contributors ID in scholarly journals

    Directory of Open Access Journals (Sweden)

    Jeonghee Im

    2015-02-01

    Full Text Available Open Researchers and Contributors ID (ORCID launched its registry services in October 2012. Consequently, adding personal information to the ORCID registry became routine work for researchers. To add ORCID to an online article, the tag needs to be included in the Journal Article Tag Suite extensible markup language file, if such a file has been produced by the publisher. Subsequently, all co-authors’ ORCID can be easily and conveniently collected and then integrated into the manuscript management system. In the current age of information and the Internet, journals need to keep pace with the surge of new standards and technologies. Editors should be able to accept and apply these new systems rapidly.

  15. International Decommissioning Symposium 2000 (IDS 2000). Final Report

    International Nuclear Information System (INIS)

    Ebadian, M.A.

    2001-01-01

    The purpose of IDS 2000 was to deliver a world-class conference on applicable global environmental issues. The objective of this conference was to publicize environmental progress of individual countries, to provide a forum for technology developer and problem-holder interaction, to facilitate environmental and technology discussions between the commercial and financial communities, and to accommodate information and education exchange between governments, industries, universities, and scientists. The scope of this project included the planning and execution of an international conference on the decommissioning of nuclear facilities, and the providing of a business forum for vendors and participants sufficient to attract service providers, technology developers, and the business and financial communities. These groups, when working together with attendees from regulatory organizations and government decision-maker groups, provide an opportunity to more effectively and efficiently expedite the decommissioning projects

  16. ID-Check: Online Concealed Information Test Reveals True Identity.

    Science.gov (United States)

    Verschuere, Bruno; Kleinberg, Bennett

    2016-01-01

    The Internet has already changed people's lives considerably and is likely to drastically change forensic research. We developed a web-based test to reveal concealed autobiographical information. Initial studies identified a number of conditions that affect diagnostic efficiency. By combining these moderators, this study investigated the full potential of the online ID-check. Participants (n = 101) tried to hide their identity and claimed a false identity in a reaction time-based Concealed Information Test. Half of the participants were presented with personal details (e.g., first name, last name, birthday), whereas the others only saw irrelevant details. Results showed that participants' true identity could be detected with high accuracy (AUC = 0.98; overall accuracy: 86-94%). Online memory detection can reliably and validly detect whether someone is hiding their true identity. This suggests that online memory detection might become a valuable tool for forensic applications. © 2015 American Academy of Forensic Sciences.

  17. Underground Storage Tank Integrated Demonstration (UST-ID)

    International Nuclear Information System (INIS)

    1994-02-01

    The DOE complex currently has 332 underground storage tanks (USTs) that have been used to process and store radioactive and chemical mixed waste generated from weapon materials production. Very little of the over 100 million gallons of high-level and low-level radioactive liquid waste has been treated and disposed of in final form. Two waste storage tank design types are prevalent across the DOE complex: single-shell wall and double-shell wall designs. They are made of stainless steel, concrete, and concrete with carbon steel liners, and their capacities vary from 5000 gallons (19 m 3 ) to 10 6 gallons (3785 m 3 ). The tanks have an overburden layer of soil ranging from a few feet to tens of feet. Responding to the need for remediation of tank waste, driven by Federal Facility Compliance Agreements (FFCAs) at all participating sites, the Underground Storage Tank Integrated Demonstration (UST-ID) Program was created by the US DOE Office of Technology Development in February 1991. Its mission is to focus the development, testing, and evaluation of remediation technologies within a system architecture to characterize, retrieve, treat to concentrate, and dispose of radioactive waste stored in USTs at DOE facilities. The ultimate goal is to provide safe and cost-effective solutions that are acceptable to the public and the regulators. The UST-ID has focused on five DOE locations: the Hanford Site, which is the host site, in Richland, Washington; the Fernald Site in Fernald, Ohio; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; the Oak Ridge Reservation in Oak Ridge, Tennessee, and the Savannah River Site in Savannah River, South Carolina

  18. Automatic ID heat load generation in ANSYS code

    International Nuclear Information System (INIS)

    Wang, Zhibi.

    1992-01-01

    Detailed power density profiles are critical in the execution of a thermal analysis using a finite element (FE) code such as ANSYS. Unfortunately, as yet there is no easy way to directly input the precise power profiles into ANSYS. A straight-forward way to do this is to hand-calculate the power of each node or element and then type the data into the code. Every time a change is made to the FE model, the data must be recalculated and reentered. One way to solve this problem is to generate a set of discrete data, using another code such as PHOTON2, and curve-fit the data. Using curve-fitted formulae has several disadvantages. It is time consuming because of the need to run a second code for generation of the data, curve-fitting, and doing the data check, etc. Additionally, because there is no generality for different beamlines or different parameters, the above work must be repeated for each case. And, errors in the power profiles due to curve-fitting result in errors in the analysis. To solve the problem once and for all and with the capability to apply to any insertion device (ID), a program for ED power profile was written in ANSYS Parametric Design Language (APDL). This program is implemented as an ANSYS command with input parameters of peak magnetic field, deflection parameter, length of ID, and distance from the source. Once the command is issued, all the heat load will be automatically generated by the code

  19. TMT approach to observatory software development process

    Science.gov (United States)

    Buur, Hanne; Subramaniam, Annapurni; Gillies, Kim; Dumas, Christophe; Bhatia, Ravinder

    2016-07-01

    The purpose of the Observatory Software System (OSW) is to integrate all software and hardware components of the Thirty Meter Telescope (TMT) to enable observations and data capture; thus it is a complex software system that is defined by four principal software subsystems: Common Software (CSW), Executive Software (ESW), Data Management System (DMS) and Science Operations Support System (SOSS), all of which have interdependencies with the observatory control systems and data acquisition systems. Therefore, the software development process and plan must consider dependencies to other subsystems, manage architecture, interfaces and design, manage software scope and complexity, and standardize and optimize use of resources and tools. Additionally, the TMT Observatory Software will largely be developed in India through TMT's workshare relationship with the India TMT Coordination Centre (ITCC) and use of Indian software industry vendors, which adds complexity and challenges to the software development process, communication and coordination of activities and priorities as well as measuring performance and managing quality and risk. The software project management challenge for the TMT OSW is thus a multi-faceted technical, managerial, communications and interpersonal relations challenge. The approach TMT is using to manage this multifaceted challenge is a combination of establishing an effective geographically distributed software team (Integrated Product Team) with strong project management and technical leadership provided by the TMT Project Office (PO) and the ITCC partner to manage plans, process, performance, risk and quality, and to facilitate effective communications; establishing an effective cross-functional software management team composed of stakeholders, OSW leadership and ITCC leadership to manage dependencies and software release plans, technical complexities and change to approved interfaces, architecture, design and tool set, and to facilitate

  20. The Virtual Solar Observatory and the Heliophysics Meta-Virtual Observatory

    Science.gov (United States)

    Gurman, Joseph B.

    2007-01-01

    The Virtual Solar Observatory (VSO) is now able to search for solar data ranging from the radio to gamma rays, obtained from space and groundbased observatories, from 26 sources at 12 data providers, and from 1915 to the present. The solar physics community can use a Web interface or an Application Programming Interface (API) that allows integrating VSO searches into other software, including other Web services. Over the next few years, this integration will be especially obvious as the NASA Heliophysics division sponsors the development of a heliophysics-wide virtual observatory (VO), based on existing VO's in heliospheric, magnetospheric, and ionospheric physics as well as the VSO. We examine some of the challenges and potential of such a "meta-VO."

  1. Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer

    International Nuclear Information System (INIS)

    Carey, Jason PW; Asirvatham, Ananthi J; Galm, Oliver; Ghogomu, Tandeih A; Chaudhary, Jaideep

    2009-01-01

    Inhibitor of differentiation 4 (Id4), a member of the Id gene family is also a dominant negative regulator of basic helix loop helix (bHLH) transcription factors. Some of the functions of Id4 appear to be unique as compared to its other family members Id1, Id2 and Id3. Loss of Id4 gene expression in many cancers in association with promoter hypermethylation has led to the proposal that Id4 may act as a tumor suppressor. In this study we provide functional evidence that Id4 indeed acts as a tumor suppressor and is part of a cancer associated epigenetic re-programming. Data mining was used to demonstrate Id4 expression in prostate cancer. Methylation specific polymerase chain reaction (MSP) analysis was performed to understand molecular mechanisms associated with Id4 expression in prostate cancer cell lines. The effect of ectopic Id4 expression in DU145 cells was determined by cell cycle analysis (3H thymidine incorporation and FACS), expression of androgen receptor, p53 and cyclin dependent kinase inhibitors p27 and p21 by a combination of RT-PCR, real time-PCR, western blot and immuno-cytochemical analysis. Id4 expression was down-regulated in prostate cancer. Id4 expression was also down-regulated in prostate cancer line DU145 due to promoter hyper-methylation. Ectopic Id4 expression in DU145 prostate cancer cell line led to increased apoptosis and decreased cell proliferation due in part by an S-phase arrest. In addition to S-phase arrest, ectopic Id4 expression in PC3 cells also resulted in prolonged G2/M phase. At the molecular level these changes were associated with increased androgen receptor (AR), p21, p27 and p53 expression in DU145 cells. The results suggest that Id4 acts directly as a tumor suppressor by influencing a hierarchy of cellular processes at multiple levels that leads to a decreased cell proliferation and change in morphology that is possibly mediated through induction of previously silenced tumor suppressors

  2. Inhibitor of differentiation 4 (Id4 is a potential tumor suppressor in prostate cancer

    Directory of Open Access Journals (Sweden)

    Carey Jason PW

    2009-06-01

    Full Text Available Abstract Background Inhibitor of differentiation 4 (Id4, a member of the Id gene family is also a dominant negative regulator of basic helix loop helix (bHLH transcription factors. Some of the functions of Id4 appear to be unique as compared to its other family members Id1, Id2 and Id3. Loss of Id4 gene expression in many cancers in association with promoter hypermethylation has led to the proposal that Id4 may act as a tumor suppressor. In this study we provide functional evidence that Id4 indeed acts as a tumor suppressor and is part of a cancer associated epigenetic re-programming. Methods Data mining was used to demonstrate Id4 expression in prostate cancer. Methylation specific polymerase chain reaction (MSP analysis was performed to understand molecular mechanisms associated with Id4 expression in prostate cancer cell lines. The effect of ectopic Id4 expression in DU145 cells was determined by cell cycle analysis (3H thymidine incorporation and FACS, expression of androgen receptor, p53 and cyclin dependent kinase inhibitors p27 and p21 by a combination of RT-PCR, real time-PCR, western blot and immuno-cytochemical analysis. Results Id4 expression was down-regulated in prostate cancer. Id4 expression was also down-regulated in prostate cancer line DU145 due to promoter hyper-methylation. Ectopic Id4 expression in DU145 prostate cancer cell line led to increased apoptosis and decreased cell proliferation due in part by an S-phase arrest. In addition to S-phase arrest, ectopic Id4 expression in PC3 cells also resulted in prolonged G2/M phase. At the molecular level these changes were associated with increased androgen receptor (AR, p21, p27 and p53 expression in DU145 cells. Conclusion The results suggest that Id4 acts directly as a tumor suppressor by influencing a hierarchy of cellular processes at multiple levels that leads to a decreased cell proliferation and change in morphology that is possibly mediated through induction of previously

  3. Psychometrics and latent structure of the IDS and QIDS with young adult students.

    Science.gov (United States)

    González, David Andrés; Boals, Adriel; Jenkins, Sharon Rae; Schuler, Eric R; Taylor, Daniel

    2013-07-01

    Students and young adults have high rates of suicide and depression, thus are a population of interest. To date, there is no normative psychometric information on the IDS and QIDS in these populations. Furthermore, there is equivocal evidence on the factor structure and subscales of the IDS. Two samples of young adult students (ns=475 and 1681) were given multiple measures to test the psychometrics and dimensionality of the IDS and QIDS. The IDS, its subscales, and QIDS had acceptable internal consistencies (αs=.79-90) and favorable convergent and divergent validity correlations. A three-factor structure and two Rasch-derived subscales best fit the IDS. The samples were collected from one university, which may influence generalizability. The IDS and QIDS are desirable measures of depressive symptoms when studying young adult students. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation.

    Science.gov (United States)

    Shaw, Laura A; Bélanger, Simon; Omilusik, Kyla D; Cho, Sunglim; Scott-Browne, James P; Nance, J Philip; Goulding, John; Lasorella, Anna; Lu, Li-Fan; Crotty, Shane; Goldrath, Ananda W

    2016-07-01

    The differentiation of helper T cells into effector subsets is critical to host protection. Transcription factors of the E-protein and Id families are important arbiters of T cell development, but their role in the differentiation of the TH1 and TFH subsets of helper T cells is not well understood. Here, TH1 cells showed more robust Id2 expression than that of TFH cells, and depletion of Id2 via RNA-mediated interference increased the frequency of TFH cells. Furthermore, TH1 differentiation was blocked by Id2 deficiency, which led to E-protein-dependent accumulation of effector cells with mixed characteristics during viral infection and severely impaired the generation of TH1 cells following infection with Toxoplasma gondii. The TFH cell-defining transcriptional repressor Bcl6 bound the Id2 locus, which provides a mechanism for the bimodal Id2 expression and reciprocal development of TH1 cells and TFH cells.

  5. GAIA virtual observatory - development and practices

    Science.gov (United States)

    Syrjäsuo, Mikko; Marple, Steve

    2010-05-01

    The Global Auroral Imaging Access, or GAIA, is a virtual observatory providing quick access to summary data from satellite and ground-based instruments that remote sense auroral precipitation (http://gaia-vxo.org). This web-based service facilitates locating data relevant to particular events by simultaneously displaying summary images from various data sets around the world. At the moment, there are GAIA server nodes in Canada, Finland, Norway and the UK. The development is an international effort and the software and metadata are freely available. The GAIA system is based on a relational database which is queried by a dedicated software suite that also creates the graphical end-user interface if such is needed. Most commonly, the virtual observatory is used interactively by using a web browser: the user provides the date and the type of data of interest. As the summary data from multiple instruments are displayed simultaneously, the user can conveniently explore the recorded data. The virtual observatory provides essentially instant access to the images originating from all major auroral instrument networks including THEMIS, NORSTAR, GLORIA and MIRACLE. The scientific, educational and outreach use is limited by creativity rather than access. The first version of the GAIA was developed at the University of Calgary (Alberta, Canada) in 2004-2005. This proof-of-concept included mainly THEMIS and MIRACLE data, which comprised of millions of summary plots and thumbnail images. However, it was soon realised that a complete re-design was necessary to increase flexibility. In the presentation, we will discuss the early history and motivation of GAIA as well as how the development continued towards the current version. The emphasis will be on practical problems and their solutions. Relevant design choices will also be highlighted.

  6. Decision Analysis Tools for Volcano Observatories

    Science.gov (United States)

    Hincks, T. H.; Aspinall, W.; Woo, G.

    2005-12-01

    Staff at volcano observatories are predominantly engaged in scientific activities related to volcano monitoring and instrumentation, data acquisition and analysis. Accordingly, the academic education and professional training of observatory staff tend to focus on these scientific functions. From time to time, however, staff may be called upon to provide decision support to government officials responsible for civil protection. Recognizing that Earth scientists may have limited technical familiarity with formal decision analysis methods, specialist software tools that assist decision support in a crisis should be welcome. A review is given of two software tools that have been under development recently. The first is for probabilistic risk assessment of human and economic loss from volcanic eruptions, and is of practical use in short and medium-term risk-informed planning of exclusion zones, post-disaster response, etc. A multiple branch event-tree architecture for the software, together with a formalism for ascribing probabilities to branches, have been developed within the context of the European Community EXPLORIS project. The second software tool utilizes the principles of the Bayesian Belief Network (BBN) for evidence-based assessment of volcanic state and probabilistic threat evaluation. This is of practical application in short-term volcano hazard forecasting and real-time crisis management, including the difficult challenge of deciding when an eruption is over. An open-source BBN library is the software foundation for this tool, which is capable of combining synoptically different strands of observational data from diverse monitoring sources. A conceptual vision is presented of the practical deployment of these decision analysis tools in a future volcano observatory environment. Summary retrospective analyses are given of previous volcanic crises to illustrate the hazard and risk insights gained from use of these tools.

  7. Protection of Hawaii's Observatories from Light Pollution

    Science.gov (United States)

    Wainscoat, Richard J.

    2018-01-01

    Maunakea Observatory, located on the island of Hawaii, is among the world darkest sites for astronomy. Strong efforts to preserve the dark night sky over the last forty years have proven successful. Artificial light presently adds only approximately 2% to the natural night sky brightness. The techniques being used to protect Maunakea from light pollution will be described, along with the challenges that are now being faced.Haleakala Observatory, located on the island of Maui, is also an excellent observing site, and is among the best sites in the United States. Lighting restrictions in Maui County are much weaker, and consequently, the night sky above Haleakala is less well protected. Haleakala is closer to Honolulu and the island of Oahu (population approximately 1 million), and the glow from Oahu makes the northwestern sky brighter.Much of the lighting across most of the United States, including Hawaii, is presently being converted to LED lighting. This provides an opportunity to replace existing poorly shielded lights with properly shielded LED fixtures, but careful spectral management is essential. It is critically important to only use LED lighting that is deficient in blue and green light. LED lighting also is easy to dim. Dimming of lights later at night, when there is no need for brighter lighting, is an important tool for reducing light pollution.Techniques used to protect astronomical observatories from light pollution are similar to the techniques that must be used to protect animals that are affected by light at night, such as endangered birds and turtles. These same techniques are compatible with recent human health related lighting recommendations from the American Medical Association.

  8. The Implementation of C-ID, R2D2 Model on Learning Reading Comprehension

    Science.gov (United States)

    Rayanto, Yudi Hari; Rusmawan, Putu Ngurah

    2016-01-01

    The purposes of this research are to find out, (1) whether C-ID, R2D2 model is effective to be implemented on learning Reading comprehension, (2) college students' activity during the implementation of C-ID, R2D2 model on learning Reading comprehension, and 3) college students' learning achievement during the implementation of C-ID, R2D2 model on…

  9. Regulation of Id2 expression in EL4 T lymphoma cells overexpressing growth hormone.

    Science.gov (United States)

    Weigent, Douglas A

    2009-01-01

    In previous studies, we have shown that overexpression of growth hormone (GH) in cells of the immune system upregulates proteins involved in cell growth and protects from apoptosis. Here, we report that overexpression of GH in EL4 T lymphoma cells (GHo) also significantly increased levels of the inhibitor of differentiation-2 (Id2). The increase in Id2 was suggested in both Id2 promoter luciferase assays and by Western analysis for Id2 protein. To identify the regulatory elements that mediate transcriptional activation by GH in the Id2 promoter, promoter deletion analysis was performed. Deletion analysis revealed that transactivation involved a 301-132bp region upstream to the Id2 transcriptional start site. The pattern in the human GHo Jurkat T lymphoma cell line paralleled that found in the mouse GHo EL4 T lymphoma cell line. Significantly less Id2 was detected in the nucleus of GHo EL4 T lymphoma cells compared to vector alone controls. Although serum increased the levels of Id2 in control vector alone cells, no difference was found in the total levels of Id2 in GHo EL4 T lymphoma cells treated with or without serum. The increase in Id2 expression in GHo EL4 T lymphoma cells measured by Id2 promoter luciferase expression and Western blot analysis was blocked by the overexpression of a dominant-negative mutant of STAT5. The results suggest that in EL4 T lymphoma cells overexpressing GH, there is an upregulation of Id2 protein that appears to involve STAT protein activity.

  10. Citizen Observatories: A Standards Based Architecture

    Science.gov (United States)

    Simonis, Ingo

    2015-04-01

    A number of large-scale research projects are currently under way exploring the various components of citizen observatories, e.g. CITI-SENSE (http://www.citi-sense.eu), Citclops (http://citclops.eu), COBWEB (http://cobwebproject.eu), OMNISCIENTIS (http://www.omniscientis.eu), and WeSenseIt (http://www.wesenseit.eu). Common to all projects is the motivation to develop a platform enabling effective participation by citizens in environmental projects, while considering important aspects such as security, privacy, long-term storage and availability, accessibility of raw and processed data and its proper integration into catalogues and international exchange and collaboration systems such as GEOSS or INSPIRE. This paper describes the software architecture implemented for setting up crowdsourcing campaigns using standardized components, interfaces, security features, and distribution capabilities. It illustrates the Citizen Observatory Toolkit, a software suite that allows defining crowdsourcing campaigns, to invite registered and unregistered participants to participate in crowdsourcing campaigns, and to analyze, process, and visualize raw and quality enhanced crowd sourcing data and derived products. The Citizen Observatory Toolkit is not a single software product. Instead, it is a framework of components that are built using internationally adopted standards wherever possible (e.g. OGC standards from Sensor Web Enablement, GeoPackage, and Web Mapping and Processing Services, as well as security and metadata/cataloguing standards), defines profiles of those standards where necessary (e.g. SWE O&M profile, SensorML profile), and implements design decisions based on the motivation to maximize interoperability and reusability of all components. The toolkit contains tools to set up, manage and maintain crowdsourcing campaigns, allows building on-demand apps optimized for the specific sampling focus, supports offline and online sampling modes using modern cell phones with

  11. Pulsating stars and the Virtual Observatory

    Science.gov (United States)

    Suárez, Juan Carlos

    2017-09-01

    Virtual Observatory is one of the most used internet-based protocols in astronomy. It has become somewhat natural to find, manage, compare, visualize and download observations from very different archives of astronomical observations with no effort. The VO technology beyond that is now being a reality for asteroseismology, not only for observations but also for theoretical models. Here I give a brief description of the most important VO tools related with asteroseismology, as well as a rough outline of the current development in this field.

  12. Recent Results from the Pierre Auger observatory

    International Nuclear Information System (INIS)

    Kampert, Karl-Heinz

    2010-01-01

    The Pierre Auger observatory is a hybrid air shower experiment which uses multiple detection techniques to investigate the origin, spectrum, and composition of ultrahigh energy cosmic rays. We present recent results on these topics and discuss their implications to the understanding the origin of the most energetic particles in nature as well as for physics beyond the Standard Model, such as violation of Lorentz invariance and 'top-down' models of cosmic ray production. Future plans, including enhancements underway at the southern site in Argentina will be presented. (author)

  13. Pulsating stars and the Virtual Observatory

    Directory of Open Access Journals (Sweden)

    Suárez Juan Carlos

    2017-01-01

    Full Text Available Virtual Observatory is one of the most used internet-based protocols in astronomy. It has become somewhat natural to find, manage, compare, visualize and download observations from very different archives of astronomical observations with no effort. The VO technology beyond that is now being a reality for asteroseismology, not only for observations but also for theoretical models. Here I give a brief description of the most important VO tools related with asteroseismology, as well as a rough outline of the current development in this field.

  14. The Virtual Solar Observatory: Progress and Diversions

    Science.gov (United States)

    Gurman, Joseph B.; Bogart, R. S.; Amezcua, A.; Hill, Frank; Oien, Niles; Davey, Alisdair R.; Hourcle, Joseph; Mansky, E.; Spencer, Jennifer L.

    2017-08-01

    The Virtual Solar Observatory (VSO) is a known and useful method for identifying and accessing solar physics data online. We review current "behind the scenes" work on the VSO, including the addition of new data providers and the return of access to data sets to which service was temporarily interrupted. We also report on the effect on software development efforts when government IT “security” initiatives impinge on finite resoruces. As always, we invite SPD members to identify data sets, services, and interfaces they would like to see implemented in the VSO.

  15. ID-pilet teeb Tallinnas võidukäiku / Anneli Lepp

    Index Scriptorium Estoniae

    Lepp, Anneli

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 12. jaan. lk 3. Tallinna transpordiameti peaökonomisti Mart Moosuse sõnul moodustas ID-pilet 60,7% ühistranspordi piletituludest, Tartus oli vastav näitaja aga alla 1%. Tartut teenindava bussifirma AS Connex Eesti finantsjuht Tiina Telling peab suure erinevuse põhjuseks asjaolu, et Tallinnas on ID-pilet paberpiletist 40-88% soodsam, Tartus hinnavahe aga puudub või on lausa negatiivne ID-pileti kahjuks. Lisa: ID-pilet

  16. A brief review of revocable ID-based public key cryptosystem

    Directory of Open Access Journals (Sweden)

    Tsu-Yang Wu

    2016-03-01

    Full Text Available The design of ID-based cryptography has received much attention from researchers. However, how to revoke the misbehaviour/compromised user in ID-based public key cryptosystem becomes an important research issue. Recently, Tseng and Tsai proposed a novel public key cryptosystem called revocable ID-based public key cryptosystem (RIBE to solve the revocation problem. Later on, numerous research papers based on the Tseng-Tsai key RIBE were proposed. In this paper, we brief review Tseng and Tsai's RIBE. We hope this review can help the readers to understand the Tseng and Tsai's revocable ID-based public key cryptosystem.

  17. Achieving Payoffs from an Industry Cloud Ecosystem at BankID

    DEFF Research Database (Denmark)

    Eaton, Ben; Hallingby, Hanne Kristine; Nesse, Per-Jonny

    2014-01-01

    BankID is an industry cloud owned by Norwegian banks. It provides electronic identity, authentication and electronic signing capabilities for banking, merchant and government services. More than 60% of the population uses BankID services. As the broader ecosystem around BankID evolved, challenges......—arising from tensions between different parts of the ecosystem—had to be resolved. The four lessons learned from the BankID case will help others to build an industry cloud and establish a healthy ecosystem to service a broad user base....

  18. Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)

    Energy Technology Data Exchange (ETDEWEB)

    Jared Verba; Michael Milvich

    2008-05-01

    Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

  19. Id-1 is not expressed in the luminal epithelial cells of mammary glands

    International Nuclear Information System (INIS)

    Uehara, Norihisa; Chou, Yu-Chien; Galvez, Jose J; Candia, Paola de; Cardiff, Robert D; Benezra, Robert; Shyamala, Gopalan

    2003-01-01

    The family of inhibitor of differentiation/DNA binding (Id) proteins is known to regulate development in several tissues. One member of this gene family, Id-1, has been implicated in mammary development and carcinogenesis. Mammary glands contain various cell types, among which the luminal epithelial cells are primarily targeted for proliferation, differentiation and carcinogenesis. Therefore, to assess the precise significance of Id-1 in mammary biology and carcinogenesis, we examined its cellular localization in vivo using immunohistochemistry. Extracts of whole mammary glands from wild type and Id-1 null mutant mice, and tissue sections from paraffin-embedded mouse mammary glands from various developmental stages and normal human breast were subjected to immunoblot and immunohistochemical analyses, respectively. In both these procedures, an anti-Id-1 rabbit polyclonal antibody was used for detection of Id-1. In immunoblot analyses, using whole mammary gland extracts, Id-1 was detected. In immunohistochemical analyses, however, Id-1 was not detected in the luminal epithelial cells of mammary glands during any stage of development, but it was detected in vascular endothelial cells. Id-1 is not expressed in the luminal epithelial cells of mammary glands

  20. COMO AS MARCAS INFLUENCIAM NA ESTRUTURAÇÃO PSÍQUICA DO SER HUMANO: UMA VISÃO SOBRE A REDE DE FAST FOOD MCDONALDS

    OpenAIRE

    José Ricardo Riambau Jahnke

    2013-01-01

    Esta dissertação de mestrado vem ao encontro de nossas inquietações sobre como se dá o fe-nômeno da adesão às marcas em detrimento de outras valorações sociais tradicionalmente aceitas e fundeadas nas habilidades pessoais de interação com seus iguais do que por ditames artificialmente construídos. Entendemos que para alcançarmos este objetivo há de se partir de uma historicidade de como uma marca ser faz existir, para tanto escolhemos a Rede de Fast Food McDonalds em virtude da mesma estar po...

  1. Generating unique IDs from patient identification data using security models

    Directory of Open Access Journals (Sweden)

    Emad A Mohammed

    2016-01-01

    Full Text Available Background: The use of electronic health records (EHRs has continued to increase within healthcare systems in the developed and developing nations. EHRs allow for increased patient safety, grant patients easier access to their medical records, and offer a wealth of data to researchers. However, various bioethical, financial, logistical, and information security considerations must be addressed while transitioning to an EHR system. The need to encrypt private patient information for data sharing is one of the foremost challenges faced by health information technology. Method: We describe the usage of the message digest-5 (MD5 and secure hashing algorithm (SHA as methods for encrypting electronic medical data. In particular, we present an application of the MD5 and SHA-1 algorithms in encrypting a composite message from private patient information. Results: The results show that the composite message can be used to create a unique one-way encrypted ID per patient record that can be used for data sharing. Conclusion: The described software tool can be used to share patient EMRs between practitioners without revealing patients identifiable data.

  2. An IDS Alerts Aggregation Algorithm Based on Rough Set Theory

    Science.gov (United States)

    Zhang, Ru; Guo, Tao; Liu, Jianyi

    2018-03-01

    Within a system in which has been deployed several IDS, a great number of alerts can be triggered by a single security event, making real alerts harder to be found. To deal with redundant alerts, we propose a scheme based on rough set theory. In combination with basic concepts in rough set theory, the importance of attributes in alerts was calculated firstly. With the result of attributes importance, we could compute the similarity of two alerts, which will be compared with a pre-defined threshold to determine whether these two alerts can be aggregated or not. Also, time interval should be taken into consideration. Allowed time interval for different types of alerts is computed individually, since different types of alerts may have different time gap between two alerts. In the end of this paper, we apply proposed scheme on DAPRA98 dataset and the results of experiment show that our scheme can efficiently reduce the redundancy of alerts so that administrators of security system could avoid wasting time on useless alerts.

  3. Generating unique IDs from patient identification data using security models.

    Science.gov (United States)

    Mohammed, Emad A; Slack, Jonathan C; Naugler, Christopher T

    2016-01-01

    The use of electronic health records (EHRs) has continued to increase within healthcare systems in the developed and developing nations. EHRs allow for increased patient safety, grant patients easier access to their medical records, and offer a wealth of data to researchers. However, various bioethical, financial, logistical, and information security considerations must be addressed while transitioning to an EHR system. The need to encrypt private patient information for data sharing is one of the foremost challenges faced by health information technology. We describe the usage of the message digest-5 (MD5) and secure hashing algorithm (SHA) as methods for encrypting electronic medical data. In particular, we present an application of the MD5 and SHA-1 algorithms in encrypting a composite message from private patient information. The results show that the composite message can be used to create a unique one-way encrypted ID per patient record that can be used for data sharing. The described software tool can be used to share patient EMRs between practitioners without revealing patients identifiable data.

  4. Molecular characterization of lactobacilli isolated from fermented idli batter

    Directory of Open Access Journals (Sweden)

    Perumal Jayaprabha Agaliya

    2013-12-01

    Full Text Available Lactic acid bacteria are non pathogenic organism widely distributed in nature typically involved in a large number of spontaneous food fermentation. The purpose of this study was to characterize the bacteriocinogenic lactobacilli from fermented idli batter which can find application in biopreservation and biomedicine. Eight most promising lactobacilli were chosen from twenty two isolates based on their spectrum of activity against other lactic acid bacteria and pathogens. The eight lactobacilli were characterized based on the various classical phenotypic tests, physiological tests and biochemical tests including various carbohydrate utilization profiles. All isolates were homo fermentative, catalase, and gelatin negative. Molecular characterization was performed by RAPD, 16S rRNA analysis, 16S ARDRA, and Multiplex PCR for species identification. RAPD was carried out using the primer R2 and M13. Five different clusters were obtained based on RAPD indicating strain level variation. 16S rRNA analysis showed 99 to 100% homology towards Lactobacillus plantarum. The restriction digestion pattern was similar for all the isolates with the restriction enzyme AluI. The subspecies were identified by performing Multiplex PCR using species specific primer. Among the five clusters, three clusters were clearly identified as Lactobacillus plantarum subsp. plantarum, Lactobacillus pentosus, and Lactobacillus plantarum subsp. argentoratensis.

  5. Time-and-ID-Based Proxy Reencryption Scheme

    Directory of Open Access Journals (Sweden)

    Kambombo Mtonga

    2014-01-01

    Full Text Available Time- and ID-based proxy reencryption scheme is proposed in this paper in which a type-based proxy reencryption enables the delegator to implement fine-grained policies with one key pair without any additional trust on the proxy. However, in some applications, the time within which the data was sampled or collected is very critical. In such applications, for example, healthcare and criminal investigations, the delegatee may be interested in only some of the messages with some types sampled within some time bound instead of the entire subset. Hence, in order to carter for such situations, in this paper, we propose a time-and-identity-based proxy reencryption scheme that takes into account the time within which the data was collected as a factor to consider when categorizing data in addition to its type. Our scheme is based on Boneh and Boyen identity-based scheme (BB-IBE and Matsuo’s proxy reencryption scheme for identity-based encryption (IBE to IBE. We prove that our scheme is semantically secure in the standard model.

  6. Protocol for VOC-Arid ID remediation performance characterization

    International Nuclear Information System (INIS)

    Tegner, B.J.; Hassig, N.L.; Last, G.V.

    1994-09-01

    The Volatile Organic Compound-Arid Integrated Demonstration (VOC-Arid ID) is a technology development program sponsored by the US Department of Energy's Office of Technology Development that is targeted to acquire, develop, demonstrate, and deploy new technologies for the remediation of VOC contaminants in the soils and groundwaters of arid DOE sites. Technologies cannot be adequately evaluated unless sufficient site characterization and technology performance data have been collection and analyzed. The responsibility for identifying these data needs has been placed largely on the Principal Investigators (PIs) developing the remediation technology, who usually are not experts in site characterization or in identification of appropriate sampling, analysis, and monitoring techniques to support the field testing. This document provides a protocol for planning the collection of data before, during, and after a test of a new technology. This generic protocol provides the PIs and project managers with a set of steps to follow. The protocol is based on a data collection planning process called the Data Quality Objectives (DQO) process, which was originally developed by the US Environmental Protection Agency and has been expanded by DOE to support site cleanup decisions. The DQO process focuses on the quality and quantity of data required to make decision. Stakeholders to the decisions must negotiate such key inputs to the process as the decision rules that will be used and the acceptable probabilities of making decision errors

  7. Improvement of the ID model for quantitative network data

    DEFF Research Database (Denmark)

    Sørensen, Peter Borgen; Damgaard, Christian Frølund; Dupont, Yoko Luise

    2015-01-01

    Many interactions are often poorly registered or even unobserved in empirical quantitative networks. Hence, the output of the statistical analyses may fail to differentiate between patterns that are statistical artefacts and those which are real characteristics of ecological networks. Such artefa......Many interactions are often poorly registered or even unobserved in empirical quantitative networks. Hence, the output of the statistical analyses may fail to differentiate between patterns that are statistical artefacts and those which are real characteristics of ecological networks......)1. This presentation will illustrate the application of the ID method based on a data set which consists of counts of visits by 152 pollinator species to 16 plant species. The method is based on two definitions of the underlying probabilities for each combination of pollinator and plant species: (1), pi...... reproduce the high number of zero valued cells in the data set and mimic the sampling distribution. 1 Sørensen et al, Journal of Pollination Ecology, 6(18), 2011, pp129-139...

  8. The Lowell Observatory Predoctoral Scholar Program

    Science.gov (United States)

    Prato, Lisa; Nofi, Larissa

    2018-01-01

    Lowell Observatory is pleased to solicit applications for our Predoctoral Scholar Fellowship Program. Now beginning its tenth year, this program is designed to provide unique research opportunities to graduate students in good standing, currently enrolled at Ph.D. granting institutions. Lowell staff research spans a wide range of topics, from astronomical instrumentation, to icy bodies in our solar system, exoplanet science, stellar populations, star formation, and dwarf galaxies. Strong collaborations, the new Ph.D. program at Northern Arizona University, and cooperative links across the greater Flagstaff astronomical community create a powerful multi-institutional locus in northern Arizona. Lowell Observatory's new 4.3 meter Discovery Channel Telescope is operating at full science capacity and boasts some of the most cutting-edge and exciting capabilities available in optical/infrared astronomy. Student research is expected to lead to a thesis dissertation appropriate for graduation at the doctoral level at the student's home institution. For more information, see http://www2.lowell.edu/rsch/predoc.php and links therein. Applications for Fall 2018 are due by May 1, 2018; alternate application dates will be considered on an individual basis.

  9. SPASE, Metadata, and the Heliophysics Virtual Observatories

    Science.gov (United States)

    Thieman, James; King, Todd; Roberts, Aaron

    2010-01-01

    To provide data search and access capability in the field of Heliophysics (the study of the Sun and its effects on the Solar System, especially the Earth) a number of Virtual Observatories (VO) have been established both via direct funding from the U.S. National Aeronautics and Space Administration (NASA) and through other funding agencies in the U.S. and worldwide. At least 15 systems can be labeled as Virtual Observatories in the Heliophysics community, 9 of them funded by NASA. The problem is that different metadata and data search approaches are used by these VO's and a search for data relevant to a particular research question can involve consulting with multiple VO's - needing to learn a different approach for finding and acquiring data for each. The Space Physics Archive Search and Extract (SPASE) project is intended to provide a common data model for Heliophysics data and therefore a common set of metadata for searches of the VO's. The SPASE Data Model has been developed through the common efforts of the Heliophysics Data and Model Consortium (HDMC) representatives over a number of years. We currently have released Version 2.1 of the Data Model. The advantages and disadvantages of the Data Model will be discussed along with the plans for the future. Recent changes requested by new members of the SPASE community indicate some of the directions for further development.

  10. Fine Guidance Sensing for Coronagraphic Observatories

    Science.gov (United States)

    Brugarolas, Paul; Alexander, James W.; Trauger, John T.; Moody, Dwight C.

    2011-01-01

    Three options have been developed for Fine Guidance Sensing (FGS) for coronagraphic observatories using a Fine Guidance Camera within a coronagraphic instrument. Coronagraphic observatories require very fine precision pointing in order to image faint objects at very small distances from a target star. The Fine Guidance Camera measures the direction to the target star. The first option, referred to as Spot, was to collect all of the light reflected from a coronagraph occulter onto a focal plane, producing an Airy-type point spread function (PSF). This would allow almost all of the starlight from the central star to be used for centroiding. The second approach, referred to as Punctured Disk, collects the light that bypasses a central obscuration, producing a PSF with a punctured central disk. The final approach, referred to as Lyot, collects light after passing through the occulter at the Lyot stop. The study includes generation of representative images for each option by the science team, followed by an engineering evaluation of a centroiding or a photometric algorithm for each option. After the alignment of the coronagraph to the fine guidance system, a "nulling" point on the FGS focal point is determined by calibration. This alignment is implemented by a fine alignment mechanism that is part of the fine guidance camera selection mirror. If the star images meet the modeling assumptions, and the star "centroid" can be driven to that nulling point, the contrast for the coronagraph will be maximized.

  11. Developing a Virtual Network of Research Observatories

    Science.gov (United States)

    Hooper, R. P.; Kirschtl, D.

    2008-12-01

    The hydrologic community has been discussing the concept of a network of observatories for the advancement of hydrologic science in areas of scaling processes, in testing generality of hypotheses, and in examining non-linear couplings between hydrologic, biotic, and human systems. The Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) is exploring the formation of a virtual network of observatories, formed from existing field studies without regard to funding source. Such a network would encourage sharing of data, metadata, field methods, and data analysis techniques to enable multidisciplinary synthesis, meta-analysis, and scientific collaboration in hydrologic and environmental science and engineering. The virtual network would strive to provide both the data and the environmental context of the data through advanced cyberinfrastructure support. The foundation for this virtual network is Water Data Services that enable the publication of time-series data collected at fixed points using a services-oriented architecture. These publication services, developed in the CUAHSI Hydrologic Information Systems project, permit the discovery of data from both academic and government sources through a single portal. Additional services under consideration are publication of geospatial data sets, immersive environments based upon site digital elevation models, and a common web portal to member sites populated with structured data about the site (such as land use history and geologic setting) to permit understanding the environmental context of the data being shared.

  12. Late summer distribution and stoichiometry of dissolved N, Si and P in the Southern Ocean near Heard and McDonald Islands on the Kerguelen Plateau

    Science.gov (United States)

    Chase, Z.; Bowie, A. R.; Blain, S.; Holmes, T.; Rayner, M.; Sherrin, K.; Tonnard, M.; Trull, T. W.

    2016-12-01

    The Kerguelen plateau in the Southern Indian Ocean is a naturally iron-fertilised region surrounded by iron-limited, High Nutrient Low Chlorophyll waters. The Heard Earth Ocean Biosphere Interaction (HEOBI) project sampled waters south of the Polar Front in the vicinity of Heard and McDonald Islands (HIMI) in January and February 2016. Fe fertilised waters over the plateau generally exhibited high phytoplankton biomass and photosynthetic competency (as in previous studies and satellite observations), but interestingly, phytoplankton biomass was low near HIMI, though photosynthetic competency was high. In plateau waters away from HIMI, silicic acid (Si) concentrations were strongly depleted in surface waters, averaging 3 μM, while nitrate concentrations were close to 25 μM. Relative to the remnant winter water, this represents an average seasonal drawdown of 32 μM Si and only 8 μM nitrate. Though absolute drawdown was lower at an HNLC reference site south of Heard Island, the drawdown ratio was similarly high (ΔSi: ΔN 4-5). The average N:P drawdown ratio was 12, typical for a diatom-dominated system (Weber and Deutsch 2010). N:P drawdown was positively correlated with Si drawdown, perhaps indicative of an impact of Fe on both seasonal Si drawdown and diatom N:P uptake (Price 2005). In the well-mixed, shallow waters (McDonald Islands, despite the apparent lack of nutrient drawdown or biomass accumulation. Mixed layers deeper than the euphotic zone are one mechanism that retains these remineralization signatures and near the islands, tidal mixing also contributes.

  13. Science Potential of a Deep Ocean Antineutrino Observatory

    International Nuclear Information System (INIS)

    Dye, S.T.

    2007-01-01

    This paper presents science potential of a deep ocean antineutrino observatory being developed at Hawaii. The observatory design allows for relocation from one site to another. Positioning the observatory some 60 km distant from a nuclear reactor complex enables precision measurement of neutrino mixing parameters, leading to a determination of neutrino mass hierarchy and θ 13 . At a mid-Pacific location the observatory measures the flux and ratio of uranium and thorium decay neutrinos from earth's mantle and performs a sensitive search for a hypothetical natural fission reactor in earth's core. A subsequent deployment at another mid-ocean location would test lateral heterogeneity of uranium and thorium in earth's mantle

  14. Availability and Access to Data from Kakioka Magnetic Observatory, Japan

    Directory of Open Access Journals (Sweden)

    Yasuhiro Minamoto

    2013-06-01

    Full Text Available The Japan Meteorological Agency (JMA is operating four geomagnetic observatories in Japan. Kakioka Magnetic Observatory (KMO, commissioned in 1913, is the oldest. The hourly records at KMO cover over almost 100 years. KMO is JMA's headquarters for geomagnetic and geoelectric observations. Almost all data are available at the KMO website free of charge for researchers. KMO and two other observatories have been certified as INTERMAGNET observatories, and quasi-real-time geomagnetic data from them are available at the INTERMAGNET website.

  15. Security and Privacy Improvements for the Belgian eID Technology

    Science.gov (United States)

    Verhaeghe, Pieter; Lapon, Jorn; de Decker, Bart; Naessens, Vincent; Verslype, Kristof

    The Belgian Electronic Identity Card enables Belgian citizens to prove their identity digitally and to sign electronic documents. At the end of 2009, every Belgian citizen older than 12 years will have such an eID card. In the future, usage of the eID card may be mandatory. However, irresponsible use of the card may cause harm to individuals.

  16. Causes of Mortality in Older People with Intellectual Disability: Results from the HA-ID Study

    Science.gov (United States)

    Oppewal, Alyt; Schoufour, Josje D.; van der Maarl, Hanne J. K.; Evenhuis, Heleen M.; Hilgenkamp, Thessa I. M.; Festen, Dederieke A.

    2018-01-01

    We aim to provide insight into the cause-specific mortality of older adults with intellectual disability (ID), with and without Down syndrome (DS), and compare this to the general population. Immediate and primary cause of death were collected through medical files of 1,050 older adults with ID, 5 years after the start of the Healthy Ageing and…

  17. Extending the Intermediate Data Structure (IDS for longitudinal historical databases to include geographic data

    Directory of Open Access Journals (Sweden)

    Finn Hedefalk

    2014-09-01

    Full Text Available The Intermediate Data Structure (IDS is a standardised database structure for longitudinal historical databases. Such a common structure facilitates data sharing and comparative research. In this study, we propose an extended version of IDS, named IDS-Geo, that also includes geographic data. The geographic data that will be stored in IDS-Geo are primarily buildings and/or property units, and the purpose of these geographic data is mainly to link individuals to places in space. When we want to assign such detailed spatial locations to individuals (in times before there were any detailed house addresses available, we often have to create tailored geographic datasets. In those cases, there are benefits of storing geographic data in the same structure as the demographic data. Moreover, we propose the export of data from IDS-Geo using an eXtensible Markup Language (XML Schema. IDS-Geo is implemented in a case study using historical property units, for the period 1804 to 1913, stored in a geographically extended version of the Scanian Economic Demographic Database (SEDD. To fit into the IDS-Geo data structure, we included an object lifeline representation of all of the property units (based on the snapshot time representation of single historical maps and poll-tax registers. The case study verifies that the IDS-Geo model is capable of handling geographic data that can be linked to demographic data.

  18. Demonstrating idAnimate : a multi-touch system for sketching and rapidly manipulating animations

    NARCIS (Netherlands)

    Quevedo Fernandez, Javier; Martens, J.B.O.S.

    2012-01-01

    This demonstration presents idAnimate, a multi-touch application for sketching animations. Thanks to the affordances provided by multitouch interfaces, idAnimate yields a novel, intuitive and easy to use animation technique named transformation-by-example, that allows users to author animations in

  19. Cloning and shake flask expression of hrIDS- Like in Pichia pastoris ...

    African Journals Online (AJOL)

    The human Iduronate-2-sulfate sulfatase (hIDS-Like) was cloned into the methylotrophic yeast Pichia pastoris under the control of alcohol oxidase promoter (AOX1) and the -mating factor signal peptide (a-factor). Six clones were identified by PCR. Using clone IDS28, the enzyme was secreted into the culture medium, ...

  20. The Mathematica package TopoID and its application to the Higgs boson production cross section

    Energy Technology Data Exchange (ETDEWEB)

    Hoff, Jens

    2016-07-15

    We present the Mathematica package TopoID which aims at the automation of several steps in multiloop calculations. The algorithm which lies at the very core of the package is described and illustrated with an example. The main features of TopoID are stated and some of them are briefly demonstrated for NLO or NNLO Higgs boson production.

  1. Rethinking Social Network Assessment for Students with Intellectual Disabilities (ID) in Postsecondary Education

    Science.gov (United States)

    Eisenman, Laura T.; Farley-Ripple, Elizabeth; Culnane, Mary; Freedman, Brian

    2013-01-01

    Social networks of persons with intellectual disabilities (ID) have been characterized as smaller and less diverse than those of typical peers. Advocates have focused on strengthening those social networks by expanding circles of social support, protection, and friendship. As young adults with ID experience increasing levels of community…

  2. Supporting co-creation with software, the idSpace platform

    NARCIS (Netherlands)

    Van Rosmalen, Peter; Boon, Jo; Bitter-Rijpkema, Marlies; Sie, Rory; Sloep, Peter

    2014-01-01

    Innovation, in general, requires teamwork among specialist of different disciplines. The idSpace project developed ideas on how teams of collaborating innovators could best be supported. These ideas were embodied in a platform that the project developed. This idSpace platform allows its users to

  3. 76 FR 46721 - Salmon-Challis National Forest, ID; Upper North Fork HFRA Ecosystem Restoration Project...

    Science.gov (United States)

    2011-08-03

    ...-Challis National Forest, ID; Upper North Fork HFRA Ecosystem Restoration Project Environmental Impact... improve the health of the ecosystem and reach the desired future condition. DATES: Comments concerning the... Ecosystem Restoration Project EIS, P.O. Box 180, 11 Casey Rd., North Fork, ID 83466. Comments may also be...

  4. 78 FR 45478 - Proposed Establishment of Class E Airspace; Salmon, ID

    Science.gov (United States)

    2013-07-29

    ...-0531; Airspace Docket No. 13-ANM-20] Proposed Establishment of Class E Airspace; Salmon, ID AGENCY... action proposes to establish Class E airspace at the Salmon VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation aid, Salmon, ID, to facilitate vectoring of Instrument Flight Rules...

  5. Clarté des idées innées ?

    DEFF Research Database (Denmark)

    Schøsler, Jørn

    2013-01-01

    Der gives en analyse af begreberne 'evidens' og 'medfødte idéer' hos Descartes og Locke samt hos de franske oplysningsfilosoffer.......Der gives en analyse af begreberne 'evidens' og 'medfødte idéer' hos Descartes og Locke samt hos de franske oplysningsfilosoffer....

  6. Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

    DEFF Research Database (Denmark)

    Gibbs-Seymour, Ian; Oka, Yasuyoshi; Rajendra, Eeson

    2015-01-01

    We show that central components of the Fanconi anemia (FA) DNA repair pathway, the tumor suppressor proteins FANCI and FANCD2 (the ID complex), are SUMOylated in response to replication fork stalling. The ID complex is SUMOylated in a manner that depends on the ATR kinase, the FA ubiquitin ligase...

  7. Muon Identification performance: hadron mis-Id measurements and RPC Muon selections

    CERN Document Server

    CMS Collaboration

    2014-01-01

    Pion, kaon, proton mis-identification probabilities as muons have been measured for different Muon ID algorithms. Results from two independent analyses are presented. The performance of a new muon ID algorithm based on matching of inner tracks with hits in muon RPC chambers is also presented.

  8. Artificial intelligence for the CTA Observatory scheduler

    Science.gov (United States)

    Colomé, Josep; Colomer, Pau; Campreciós, Jordi; Coiffard, Thierry; de Oña, Emma; Pedaletti, Giovanna; Torres, Diego F.; Garcia-Piquer, Alvaro

    2014-08-01

    The Cherenkov Telescope Array (CTA) project will be the next generation ground-based very high energy gamma-ray instrument. The success of the precursor projects (i.e., HESS, MAGIC, VERITAS) motivated the construction of this large infrastructure that is included in the roadmap of the ESFRI projects since 2008. CTA is planned to start the construction phase in 2015 and will consist of two arrays of Cherenkov telescopes operated as a proposal-driven open observatory. Two sites are foreseen at the southern and northern hemispheres. The CTA observatory will handle several observation modes and will have to operate tens of telescopes with a highly efficient and reliable control. Thus, the CTA planning tool is a key element in the control layer for the optimization of the observatory time. The main purpose of the scheduler for CTA is the allocation of multiple tasks to one single array or to multiple sub-arrays of telescopes, while maximizing the scientific return of the facility and minimizing the operational costs. The scheduler considers long- and short-term varying conditions to optimize the prioritization of tasks. A short-term scheduler provides the system with the capability to adapt, in almost real-time, the selected task to the varying execution constraints (i.e., Targets of Opportunity, health or status of the system components, environment conditions). The scheduling procedure ensures that long-term planning decisions are correctly transferred to the short-term prioritization process for a suitable selection of the next task to execute on the array. In this contribution we present the constraints to CTA task scheduling that helped classifying it as a Flexible Job-Shop Problem case and finding its optimal solution based on Artificial Intelligence techniques. We describe the scheduler prototype that uses a Guarded Discrete Stochastic Neural Network (GDSN), for an easy representation of the possible long- and short-term planning solutions, and Constraint

  9. Overestimation of the 25(OH)D serum concentration with the automated IDS EIA kit.

    Science.gov (United States)

    Cavalier, Etienne; Huberty, Véronique; Cormier, Catherine; Souberbielle, Jean-Claude

    2011-02-01

    We have recently observed an increasing number of patients presenting very high serum levels of 25-hydroxyvitamin D [25(OH)D] (> 150 ng/mL), which, in all cases, had been measured with the IDS EIA kit adapted on different "open" automated platforms. We performed a comparison between the IDS EIA kit adapted on two different "open"automated platforms and the DiaSorin RIA. We found a systematic bias (higher levels with the IDS EIA kit) for concentrations more than 50-60 ng/mL that was less obvious when the IDS EIA was used in its manual procedure. We thus suggest to use the IDS EIA kit in its manual procedure rather than to adapt it on an automated platform, and to interpret cautiously a 25(OH)D greater than 100 ng/mL with this kit. Copyright © 2011 American Society for Bone and Mineral Research.

  10. REFORMASI PEMAHAMAN TEORI MAQᾹṢID SYARIAH Analisis Pendekatan Sistem Jasser Auda

    Directory of Open Access Journals (Sweden)

    Muhammad Iqbal Fasa

    2016-12-01

    Full Text Available This paper attempts to offer reform ideas Jasser Auda thought related reforms theoretical understanding of maqᾱṣid sharia. The systems approach is done by Auda critize the theory of classical maqᾱṣid more likely to hierarchical and narrow mindset. The classical maqᾱṣid pressure a point more on protection and preservation. Whereas the new maqᾱṣid theory emphasizes development (construction, development and rights (rights. Thus, Auda developed the concept of human development as the main target of maslahah (public interest. Auda offers the systems approach, namely: cognitive nature; interrelated; wholeness; openness; multi dimentionality and purposefulness. At the end of the discussion in this paper, the authors develop the idea of Jasser Auda by offering Sharia Maqᾱṣid concept in the context of Islamic Economics

  11. The Steward Observatory asteroid relational database

    Science.gov (United States)

    Sykes, Mark V.; Alvarezdelcastillo, Elizabeth M.

    1991-01-01

    The Steward Observatory Asteroid Relational Database (SOARD) was created as a flexible tool for undertaking studies of asteroid populations and sub-populations, to probe the biases intrinsic to asteroid databases, to ascertain the completeness of data pertaining to specific problems, to aid in the development of observational programs, and to develop pedagogical materials. To date, SOARD has compiled an extensive list of data available on asteroids and made it accessible through a single menu-driven database program. Users may obtain tailored lists of asteroid properties for any subset of asteroids or output files which are suitable for plotting spectral data on individual asteroids. The program has online help as well as user and programmer documentation manuals. The SOARD already has provided data to fulfill requests by members of the astronomical community. The SOARD continues to grow as data is added to the database and new features are added to the program.

  12. Punctuated Evolution of Volcanology: An Observatory Perspective

    Science.gov (United States)

    Burton, W. C.; Eichelberger, J. C.

    2010-12-01

    Volcanology from the perspective of crisis prediction and response-the primary function of volcano observatories-is influenced both by steady technological advances and singular events that lead to rapid changes in methodology and procedure. The former can be extrapolated somewhat, while the latter are surprises or shocks. Predictable advances include the conversion from analog to digital systems and the exponential growth of computing capacity and data storage. Surprises include eruptions such as 1980 Mount St Helens, 1985 Nevado del Ruiz, 1989-1990 Redoubt, 1991 Pinatubo, and 2010 Eyjafjallajokull; the opening of GPS to civilian applications, and the advent of an open Russia. Mount St Helens switched the rationale for volcanology in the USGS from geothermal energy to volcano hazards, Ruiz and Pinatubo emphasized the need for international cooperation for effective early warning, Redoubt launched the effort to monitor even remote volcanoes for purposes of aviation safety, and Eyjafjallajokull hammered home the need for improved ash-dispersion and engine-tolerance models; better GPS led to a revolution in volcano geodesy, and the new Russian Federation sparked an Alaska-Kamchatka scientific exchange. The pattern has been that major funding increases for volcano hazards occur after these unpredictable events, which suddenly expose a gap in capabilities, rather than out of a calculated need to exploit technological advances or meet a future goal of risk mitigation. It is up to the observatory and national volcano hazard program to leverage these sudden funding increases into a long-term, sustainable business model that incorporates both the steadily increasing costs of staff and new technology and prepares for the next volcano crisis. Elements of the future will also include the immediate availability on the internet of all publically-funded volcano data, and subscribable, sophisticated hazard alert systems that run computational, fluid dynamic eruption models. These

  13. In situ vector calibration of magnetic observatories

    Directory of Open Access Journals (Sweden)

    A. Gonsette

    2017-09-01

    Full Text Available The goal of magnetic observatories is to measure and provide a vector magnetic field in a geodetic coordinate system. For that purpose, instrument set-up and calibration are crucial. In particular, the scale factor and orientation of a vector magnetometer may affect the magnetic field measurement. Here, we highlight the baseline concept and demonstrate that it is essential for data quality control. We show how the baselines can highlight a possible calibration error. We also provide a calibration method based on high-frequency absolute measurements. This method determines a transformation matrix for correcting variometer data suffering from scale factor and orientation errors. We finally present a practical case where recovered data have been successfully compared to those coming from a reference magnetometer.

  14. The sunspot databases of the Debrecen Observatory

    Science.gov (United States)

    Baranyi, Tünde; Gyori, Lajos; Ludmány, András

    2015-08-01

    We present the sunspot data bases and online tools available in the Debrecen Heliophysical Observatory: the DPD (Debrecen Photoheliographic Data, 1974 -), the SDD (SOHO/MDI-Debrecen Data, 1996-2010), the HMIDD (SDO/HMI-Debrecen Data, HMIDD, 2010-), the revised version of Greenwich Photoheliographic Data (GPR, 1874-1976) presented together with the Hungarian Historical Solar Drawings (HHSD, 1872-1919). These are the most detailed and reliable documentations of the sunspot activity in the relevant time intervals. They are very useful for studying sunspot group evolution on various time scales from hours to weeks. Time-dependent differences between the available long-term sunspot databases are investigated and cross-calibration factors are determined between them. This work has received funding from the European Community's Seventh Framework Programme (FP7/2012-2015) under grant agreement No. 284461 (eHEROES).

  15. MMS Observatory Thermal Vacuum Results Contamination Summary

    Science.gov (United States)

    Rosecrans, Glenn P.; Errigo, Therese; Brieda, Lubos

    2014-01-01

    The MMS mission is a constellation of 4 observatories designed to investigate the fundamental plasma physics of reconnection in the Earths magnetosphere. Each spacecraft has undergone extensive environmental testing to prepare it for its minimum 2 year mission. The various instrument suites measure electric and magnetic fields, energetic particles, and plasma composition. Thermal vacuum testing was conducted at the Naval Research Laboratory (NRL) in their Big Blue vacuum chamber. The individual spacecraft were tested and enclosed in a cryopanel enclosure called a Hamster cage. Specific contamination control validations were actively monitored by several QCMs, a facility RGA, and at times, with 16 Ion Gauges. Each spacecraft underwent a bakeout phase, followed by 4 thermal cycles. Unique aspects of the TV environment included slow pump downs with represses, thruster firings, Helium identification, and monitoring pressure spikes with Ion gauges. Various data from these TV tests will be shown along with lessons learned.

  16. Meteorological observatory for Antarctic data collection

    International Nuclear Information System (INIS)

    Grigioni, P.; De Silvestri, L.

    1996-01-01

    In the last years, a great number of automatic weather stations was installed in Antarctica, with the aim to examine closely the weather and climate of this region and to improve the coverage of measuring points on the Antarctic surface. In 1987 the Italian Antarctic Project started to set up a meteorological network, in an area not completely covered by other countries. Some of the activities performed by the meteorological observatory, concerning technical functions such as maintenance of the AWS's and the execution of radio soundings, or relating to scientific purposes such as validation and elaboration of collected data, are exposed. Finally, some climatological considerations on the thermal behaviour of the Antarctic troposphere such as 'coreless winter', and on the wind field, including katabatic flows in North Victoria Land are described

  17. Virtual Observatory: From Concept to Implementation

    Science.gov (United States)

    Djorgovski, S. G.; Williams, R.

    2005-12-01

    We review the origins of the Virtual Observatory (VO) concept, and the current status of the efforts in this field. VO is the response of the astronomical community to the challenges posed by the modern massive and complex data sets. It is a framework in which information technology is harnessed to organize, maintain, and explore the rich information content of the exponentially growing data sets, and to enable a qualitatively new science to be done with them. VO will become a complete, open, distributed, web-based framework for astronomy of the early 21st century. A number of significant efforts worldwide are now striving to convert this vision into reality. The technological and methodological challenges posed by the information-rich astronomy are also common to many other fields. We see a fundamental change in the way all science is done, driven by the information technology revolution.

  18. SOFIA: The Next Generation Airborne Observatory

    Science.gov (United States)

    Dunham, Edward; Witteborn, Fred C. (Technical Monitor)

    1995-01-01

    SOFIA, the Stratospheric Observatory For Infrared Astronomy, will carry a 2.5 meter telescope into the stratosphere on 160 7.5 hour flights per year. At stratospheric altitudes SOFIA will operate above 99% of the water vapor in the Earth's atmosphere, allowing observation of wide regions of the infrared spectrum that are totally obscured from even the best ground-based sites. Its mobility and long range will allow worldwide observation of ephemeral events such as occultations and eclipses. SOFIA will be developed jointly by NASA and DARA, the German space agency. It has been included in the President's budget request to Congress for a development start in FY96 (this October!) and enjoys strong support in Germany. This talk will cover SOFIA's scientific goals, technical characteristics, science operating plan, and political status.

  19. The Solar Connections Observatory for Planetary Environments

    Science.gov (United States)

    Oliversen, Ronald J.; Harris, Walter M.; Oegerle, William R. (Technical Monitor)

    2002-01-01

    The NASA Sun-Earth Connection theme roadmap calls for comparative study of how the planets, comets, and local interstellar medium (LISM) interact with the Sun and respond to solar variability. Through such a study we advance our understanding of basic physical plasma and gas dynamic processes, thus increasing our predictive capabilities for the terrestrial, planetary, and interplanetary environments where future remote and human exploration will occur. Because the other planets have lacked study initiatives comparable to the terrestrial ITM, LWS, and EOS programs, our understanding of the upper atmospheres and near space environments on these worlds is far less detailed than our knowledge of the Earth. To close this gap we propose a mission to study {\\it all) of the solar interacting bodies in our planetary system out to the heliopause with a single remote sensing space observatory, the Solar Connections Observatory for Planetary Environments (SCOPE). SCOPE consists of a binocular EUV/FUV telescope operating from a remote, driftaway orbit that provides sub-arcsecond imaging and broadband medium resolution spectro-imaging over the 55-290 nm bandpass, and high (R>10$^{5}$ resolution H Ly-$\\alpha$ emission line profile measurements of small scale planetary and wide field diffuse solar system structures. A key to the SCOPE approach is to include Earth as a primary science target. From its remote vantage point SCOPE will be able to observe auroral emission to and beyond the rotational pole. The other planets and comets will be monitored in long duration campaigns centered when possible on solar opposition when interleaved terrestrial-planet observations can be used to directly compare the response of both worlds to the same solar wind stream and UV radiation field. Using a combination of observations and MHD models, SCOPE will isolate the different controlling parameters in each planet system and gain insight into the underlying physical processes that define the

  20. Towards a new Mercator Observatory Control System

    Science.gov (United States)

    Pessemier, W.; Raskin, G.; Prins, S.; Saey, P.; Merges, F.; Padilla, J. P.; Van Winckel, H.; Waelkens, C.

    2010-07-01

    A new control system is currently being developed for the 1.2-meter Mercator Telescope at the Roque de Los Muchachos Observatory (La Palma, Spain). Formerly based on transputers, the new Mercator Observatory Control System (MOCS) consists of a small network of Linux computers complemented by a central industrial controller and an industrial real-time data communication network. Python is chosen as the high-level language to develop flexible yet powerful supervisory control and data acquisition (SCADA) software for the Linux computers. Specialized applications such as detector control, auto-guiding and middleware management are also integrated in the same Python software package. The industrial controller, on the other hand, is connected to the majority of the field devices and is targeted to run various control loops, some of which are real-time critical. Independently of the Linux distributed control system (DCS), this controller makes sure that high priority tasks such as the telescope motion, mirror support and hydrostatic bearing control are carried out in a reliable and safe way. A comparison is made between different controller technologies including a LabVIEW embedded system, a PROFINET Programmable Logic Controller (PLC) and motion controller, and an EtherCAT embedded PC (soft-PLC). As the latter is chosen as the primary platform for the lower level control, a substantial part of the software is being ported to the IEC 61131-3 standard programming languages. Additionally, obsolete hardware is gradually being replaced by standard industrial alternatives with fast EtherCAT communication. The use of Python as a scripting language allows a smooth migration to the final MOCS: finished parts of the new control system can readily be commissioned to replace the corresponding transputer units of the old control system with minimal downtime. In this contribution, we give an overview of the systems design, implementation details and the current status of the project.

  1. PERSONAL BRANDING PRABOWO SUBIANTO (ANALISIS ISI KUANTITATIF PERSONAL BRANDING PRABOWO SUBIANTO DI SITUS BERITA ONLINE REPUBLIKA.CO.ID DAN TEMPO.CO.ID TANGGAL 9 JUNI - 9 JULI 2014

    Directory of Open Access Journals (Sweden)

    Hendro Agus Prakoso

    2016-09-01

    berita kedua media tersebut. Frekuensi berita berjumlah 107 di Republika.co.id dan 51 berita di Tempo.co.id Ragam berita Republika.co.id didominasi konsep Spesialisasi sebesar 22,4% dari 107 berita, sedangkan pada Tempo.co.id didominasi konsep Nama baik sebesar 23,5% dari 51 berita. Sumber berita pada Republika.co.id mayoritas berasal dari Liputan langsung sebesar 42,9% dari 107 berita sedangkan pada Tempo.co.id mayoritas berasal dari Intelektual sebesar 54,9% dari 51 berita.

  2. Electricity and gas market Observatory - 2. Quarter of 2011

    International Nuclear Information System (INIS)

    2011-06-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  3. Electricity and gas market Observatory - 4. Quarter of 2010

    International Nuclear Information System (INIS)

    2010-12-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  4. Electricity and gas market Observatory - 3. Quarter of 2012

    International Nuclear Information System (INIS)

    2012-09-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  5. University Observatory, Ludwig-Maximilians-Universität

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    The University Observatory of Ludwig-Maximilians-Universität was founded in 1816. Astronomers who worked or graduated at the Munich Observatory include: Fraunhofer, Soldner, Lamont, Seeliger and Karl Schwarzschild. At present four professors and ten staff astronomers work here. Funding comes from the Bavarian Government, the German Science Foundation, and other German and European research progra...

  6. Electricity and gas market Observatory - 1. Quarter of 2012

    International Nuclear Information System (INIS)

    2012-03-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  7. Electricity and gas market Observatory - 4. Quarter of 2011

    International Nuclear Information System (INIS)

    2011-12-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  8. Electricity and gas market Observatory - 3. Quarter of 2011

    International Nuclear Information System (INIS)

    2011-09-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  9. Electricity and gas market Observatory - 4. Quarter of 2012

    International Nuclear Information System (INIS)

    2012-12-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  10. Electricity and gas market Observatory - 2. Quarter of 2012

    International Nuclear Information System (INIS)

    2012-06-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  11. Electricity and gas market Observatory - 1. Quarter of 2011

    International Nuclear Information System (INIS)

    2011-03-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  12. Science requirements and the design of cabled ocean observatories

    Directory of Open Access Journals (Sweden)

    H. Mikada

    2006-06-01

    Full Text Available The ocean sciences are beginning a new phase in which scientists will enter the ocean environment and adaptively observe the Earth-Ocean system through remote control of sensors and sensor platforms. This new ocean science paradigm will be implemented using innovative facilities called ocean observatories which provide unprecedented levels of power and communication to access and manipulate real-time sensor networks deployed within many different environments in the ocean basins. Most of the principal design drivers for ocean observatories differ from those for commercial submarine telecommunications systems. First, ocean observatories require data to be input and output at one or more seafloor nodes rather than at a few land terminuses. Second, ocean observatories must distribute a lot of power to the seafloor at variable and fluctuating rates. Third, the seafloor infrastructure for an ocean observatory inherently requires that the wet plant be expandable and reconfigurable. Finally, because the wet communications and power infrastructure is comparatively complex, ocean observatory infrastructure must be designed for low life cycle cost rather than zero maintenance. The origin of these differences may be understood by taking a systems engineering approach to ocean observatory design through examining the requirements derived from science and then going through the process of iterative refinement to yield conceptual and physical designs. This is illustrated using the NEPTUNE regional cabled observatory power and data communications sub-systems.

  13. Electricity and gas market Observatory - 1. Quarter of 2013

    International Nuclear Information System (INIS)

    2013-03-01

    The purpose of the Observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. Since 2013, it also covers the wholesale CO 2 market. This Observatory is updated every three months and data are available on CRE web site (www.cre.fr)

  14. Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer

    International Nuclear Information System (INIS)

    Noetzel, Erik; Veeck, Jürgen; Niederacher, Dieter; Galm, Oliver; Horn, Felicitas; Hartmann, Arndt; Knüchel, Ruth; Dahl, Edgar

    2008-01-01

    Inhibitor of DNA binding/Inhibitor of differentiation 4 (ID4) is a critical factor for cell proliferation and differentiation in normal vertebrate development. ID4 has regulative functions for differentiation and growth of the developing brain. The role of ID1, ID2 and ID3 are expected to be oncogenic due to their overexpression in pancreatic cancer and colorectal adenocarcinomas, respectively. Aside from these findings, loss of ID3 expression was demonstrated in ovarian cancer. The aim of the present study was to reveal the factual role of ID4 in carcinogenesis in more detail, since its role for the pathogenesis of human breast cancer has been discussed controversially, assigning both oncogenic and tumour suppressive functions. ID4 promoter methylation, ID4 mRNA expression and ID4 protein expression were analysed in primary human breast cancer specimens using methylation-specific PCR (MSP) (n=170), semiquantitative realtime RT-PCR (n=46) and immunhistochemistry (n=3), respectively. In order to demonstrate a functional association of ID4 promoter methylation with its gene silencing, we performed DNA demethylation analysis with four human breast cell lines using MSP and semiquantitative realtime RT-PCR. In addition, we performed correlations of ID4 promoter methylation with ID4 mRNA and ID4 protein expression in matched samples of breast tumour and corresponding normal tissue. We carried out statistical analyses in order to find correlations between ID4 promoter methylation and clinicopathological parameters. Frequent ID4 promoter methylation was observed in primary breast cancer samples (69%, 117/170). We found a tight correlation (P<0.0001) between ID4 promoter methylation and loss of ID4 expression in primary breast cancer 3 specimens. Demethylating treatment with breast cancer cell lines was associated with clear ID4 mRNA re-expression. Tumours with ID4 promoter methylation showed distinct loss of ID4 expression on both transcription and protein level

  15. Bio-fortification and shelf-life extension of idli batter using curry leaves (Murraya koenigii).

    Science.gov (United States)

    Chelliah, R; Ramakrishnan, S R; Premkumar, D; Antony, U

    2016-06-01

    Among several traditional foods of India, idli is one of the most popular and commonly consumed steamed products. A new method of adding Murraya koenigii (curry leaves) to idli batter as a vehicle for fortification and extension of shelf-life has been developed. Dried curry leaves powder was incorporated with other ingredients like rice and dehusked black gram in different proportions to optimize the most palatable formulation. Rate of fermentation and microbial changes in the batter; nutritional qualities, texture and sensory properties of the prepared product were assessed. Incorporation of curry leaves powder (5 %) in idli batter increased the shelf-life and also increased the flavour, texture and appearance of the idli. The calcium content of the prepared idli was 10 times more than that of the control idli, while dietary fiber content increased by 18.6 %. Anti-microbial activity of the curry leaves in idli batter extended the shelf-life from 2 to 5 days when stored at 30 °C.

  16. An online ID identification system for liquefied-gas cylinder plant

    Science.gov (United States)

    He, Jin; Ding, Zhenwen; Han, Lei; Zhang, Hao

    2017-11-01

    An automatic ID identification system for gas cylinders' online production was developed based on the production conditions and requirements of the Technical Committee for Standardization of Gas Cylinders. A cylinder ID image acquisition system was designed to improve the image contrast of ID regions on gas cylinders against the background. Then the ID digits region was located by the CNN template matching algorithm. Following that, an adaptive threshold method based on the analysis of local average grey value and standard deviation was proposed to overcome defects of non-uniform background in the segmentation results. To improve the single digit identification accuracy, two BP neural networks were trained respectively for the identification of all digits and the easily confusable digits. If the single digit was classified as one of confusable digits by the former BP neural network, it was further tested by the later one, and the later result was taken as the final identification result of this single digit. At last, the majority voting was adopted to decide the final identification result for the 6-digit cylinder ID. The developed system was installed on a production line of a liquefied-petroleum-gas cylinder plant and worked in parallel with the existing weighing step on the line. Through the field test, the correct identification rate for single ID digit was 94.73%, and none of the tested 2000 cylinder ID was misclassified through the majority voting.

  17. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells.

    Science.gov (United States)

    Mody, Avani A; Wordinger, Robert J; Clark, Abbot F

    2017-02-01

    Increased expression of TGF-β2 in primary open-angle glaucoma (POAG) aqueous humor (AH) and trabecular meshwork (TM) causes deposition of extracellular matrix (ECM) in the TM and elevated IOP. Bone morphogenetic proteins (BMPs) regulate TGF-β2-induced ECM production. The underlying mechanism for BMP4 inhibition of TGF-β2-induced fibrosis remains undetermined. Bone morphogenic protein 4 induces inhibitor of DNA binding proteins (ID1, ID3), which suppress transcription factor activities to regulate gene expression. Our study will determine whether ID1and ID3 proteins are downstream targets of BMP4, which attenuates TGF-β2 induction of ECM proteins in TM cells. Primary human TM cells were treated with BMP4, and ID1 and ID3 mRNA, and protein expression was determined by quantitative PCR (Q-PCR) and Western immunoblotting. Intracellular ID1 and ID3 protein localization was studied by immunocytochemistry. Transformed human TM cells (GTM3 cells) were transfected with ID1 or ID3 expression vectors to determine their potential inhibitory effects on TGF-β2-induced fibronectin and plasminogen activator inhibitor-I (PAI-1) protein expression. Basal expression of ID1-3 was detected in primary human TM cells. Bone morphogenic protein 4 significantly induced early expression of ID1 and ID3 mRNA (P protein in primary TM cells, and a BMP receptor inhibitor blocked this induction. Overexpression of ID1 and ID3 significantly inhibited TGF-β2-induced expression of fibronectin and PAI-1 in TM cells (P protein 4 induced ID1 and ID3 expression suppresses TGF-β2 profibrotic activity in human TM cells. In the future, targeting specific regulators may control the TGF-β2 profibrotic effects on the TM, leading to disease modifying IOP lowering therapies.

  18. The Self-Identity Protein IdsD Is Communicated between Cells in Swarming Proteus mirabilis Colonies.

    Science.gov (United States)

    Saak, Christina C; Gibbs, Karine A

    2016-12-15

    Proteus mirabilis is a social bacterium that is capable of self (kin) versus nonself recognition. Swarming colonies of this bacterium expand outward on surfaces to centimeter-scale distances due to the collective motility of individual cells. Colonies of genetically distinct populations remain separate, while those of identical populations merge. Ids proteins are essential for this recognition behavior. Two of these proteins, IdsD and IdsE, encode identity information for each strain. These two proteins bind in vitro in an allele-restrictive manner. IdsD-IdsE binding is correlated with the merging of populations, whereas a lack of binding is correlated with the separation of populations. Key questions remained about the in vivo interactions of IdsD and IdsE, specifically, whether IdsD and IdsE bind within single cells or whether IdsD-IdsE interactions occur across neighboring cells and, if so, which of the two proteins is exchanged. Here we demonstrate that IdsD must originate from another cell to communicate identity and that this nonresident IdsD interacts with IdsE resident in the recipient cell. Furthermore, we show that unbound IdsD in recipient cells does not cause cell death and instead appears to contribute to a restriction in the expansion radius of the swarming colony. We conclude that P. mirabilis communicates IdsD between neighboring cells for nonlethal kin recognition, which suggests that the Ids proteins constitute a type of cell-cell communication. We demonstrate that self (kin) versus nonself recognition in P. mirabilis entails the cell-cell communication of an identity-encoding protein that is exported from one cell and received by another. We further show that this intercellular exchange affects swarm colony expansion in a nonlethal manner, which adds social communication to the list of potential swarm-related regulatory factors. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  19. Overexpression of inhibitor of DNA-binding (ID)-1 protein related to angiogenesis in tumor advancement of ovarian cancers

    International Nuclear Information System (INIS)

    Maw, Min Khine; Fujimoto, Jiro; Tamaya, Teruhiko

    2009-01-01

    The inhibitor of DNA-binding (ID) has been involved in cell cycle regulation, apoptosis and angiogenesis. This prompted us to study ID functions in tumor advancement of ovarian cancers. Sixty patients underwent surgery for ovarian cancers. In ovarian cancers, the levels of ID-1, ID-2 and ID-3 mRNAs were determined by real-time reverse transcription-polymerase chain reaction. The histoscore with the localization of ID-1 was determined by immunohistochemistry. Patient prognosis was analyzed with a 36-month survival rate. Microvessel counts were determined by immunohistochemistry for CD34 and factor VIII-related antigen. ID-1 histoscores and mRNA levels both significantly (p < 0.001) increased in ovarian cancers according to clinical stage, regardless of histopathological type. Furthermore, 30 patients with high ID-1 expression had a lower survival rate (53%) compared to patients with low ID-1 expression (80%). ID-1 histoscores and mRNA levels significantly (p < 0.0001) correlated with microvessel counts in ovarian cancers. ID-1 increased in ovarian cancer cells during tumor progression. Moreover, ID-1 expression levels correlated with microvessel counts. Therefore, ID-1 might work on tumor advancement via angiogenesis and is considered to be a candidate for a prognostic indicator in ovarian cancers

  20. Increased Inhibitor of Differentiation 4 (Id4 Expression in Glioblastoma: A Tissue Microarray Study

    Directory of Open Access Journals (Sweden)

    Weifin Zeng, Elisabeth J. Rushing, Daniel P. Hartmann, Norio Azumi

    2010-01-01

    Full Text Available Background: The inhibitor of differentiation/DNA binding protein family (Id1-4 is involved in cell cycle control, tumorigenesis and angiogenesis through the negative regulation of helix-loop-helix transcription factors. Of these proteins, Id4 is known to play an important role in neural stem cell differentiation, and deregulation has been implicated in glial neoplasia. However, the expression and significance of Id4 in astrocytomas has not been fully addressed. Herein we report the differential expression of Id4 in astrocytomas of various grades using tissue microarrays (TMA and immunohistochemistry (IHC. Design: The GBM TMA was constructed from 53 archival cases at Georgetown University Hospital and a TMA with normal brain controls and grades II-III astrocytoma was obtained from Cybrdi (Rockville, MD. TMA sections were stained with Id4 antibody and the slides were scored according to the percentage of staining astrocytic nuclei (<9% -, 10-50% +, >51% ++. The Fisher Exact test was used to test for statistical significance. Results: Nuclear staining for Id4 was seen in 73.58% GBMs, 25% grade III, and 12.5% grade II astrocytomas; staining was absent in normal brain tissue. There was a statistically significant difference between GBM and grades II, III astrocytoma (p <0.01. Significant Id4 expression was not detected in normal brain. Conclusions: Our study confirms the frequent upregulation of Id4 expression in GBM, which lends support to its role in tumorigenesis, possibly in the transformation of low to high-grade astrocytoma (i.e. GBM. Further studies are warranted to determine the precise role of Id4 in glial neoplasia and its potential use in targeted therapy for GBM.

  1. Designing Observatories for the Hydrologic Sciences

    Science.gov (United States)

    Hooper, R. P.

    2004-05-01

    The need for longer-term, multi-scale, coherent, and multi-disciplinary data to test hypotheses in hydrologic science has been recognized by numerous prestigious review panels over the past decade (e.g. NRC's Basic Research Opportunities in Earth Science). Designing such observatories has proven to be a challenge not only on scientific, but also technological, economic and even sociologic levels. The Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) has undertaken a "paper" prototype design of a hydrologic observatory (HO) for the Neuse River Basin, NC and plans to solicit proposals and award grants to develop implementation plans for approximately 10 basins (which may be defined by topographic or groundwater divides) during the summer of 2004. These observatories are envisioned to be community resources with data available to all scientists, with support facilities to permit their use by both local and remote investigators. This paper presents the broad design concepts which were developed from a national team of scientists for the Neuse River Basin Prototype. There are three fundamental characteristics of a watershed or river basin that are critical for answering the major scientific questions proposed by the NRC to advance hydrologic, biogeochemical and ecological sciences: (1) the store and flux of water, sediment, nutrients and contaminants across interfaces at multiple scales must be identified; (2) the residence time of these constituents, and (3) their flowpaths and response spectra to forcing must be estimated. "Stores" consist of subsurface, land surface and atmospheric volumes partitioned over the watershed. The HO will require "core measurements" which will serve the communities of hydrologic science for long range research questions. The core measurements will also provide context for shorter-term or hypothesis-driven research investigations. The HO will support "mobile measurement facilities" designed to support teams

  2. GROSS- GAMMA RAY OBSERVATORY ATTITUDE DYNAMICS SIMULATOR

    Science.gov (United States)

    Garrick, J.

    1994-01-01

    The Gamma Ray Observatory (GRO) spacecraft will constitute a major advance in gamma ray astronomy by offering the first opportunity for comprehensive observations in the range of 0.1 to 30,000 megaelectronvolts (MeV). The Gamma Ray Observatory Attitude Dynamics Simulator, GROSS, is designed to simulate this mission. The GRO Dynamics Simulator consists of three separate programs: the Standalone Profile Program; the Simulator Program, which contains the Simulation Control Input/Output (SCIO) Subsystem, the Truth Model (TM) Subsystem, and the Onboard Computer (OBC) Subsystem; and the Postprocessor Program. The Standalone Profile Program models the environment of the spacecraft and generates a profile data set for use by the simulator. This data set contains items such as individual external torques; GRO spacecraft, Tracking and Data Relay Satellite (TDRS), and solar and lunar ephemerides; and star data. The Standalone Profile Program is run before a simulation. The SCIO subsystem is the executive driver for the simulator. It accepts user input, initializes parameters, controls simulation, and generates output data files and simulation status display. The TM subsystem models the spacecraft dynamics, sensors, and actuators. It accepts ephemerides, star data, and environmental torques from the Standalone Profile Program. With these and actuator commands from the OBC subsystem, the TM subsystem propagates the current state of the spacecraft and generates sensor data for use by the OBC and SCIO subsystems. The OBC subsystem uses sensor data from the TM subsystem, a Kalman filter (for attitude determination), and control laws to compute actuator commands to the TM subsystem. The OBC subsystem also provides output data to the SCIO subsystem for output to the analysts. The Postprocessor Program is run after simulation is completed. It generates printer and CRT plots and tabular reports of the simulated data at the direction of the user. GROSS is written in FORTRAN 77 and

  3. The Rapid Ice Sheet Change Observatory (RISCO)

    Science.gov (United States)

    Morin, P.; Howat, I. M.; Ahn, Y.; Porter, C.; McFadden, E. M.

    2010-12-01

    The recent expansion of observational capacity from space has revealed dramatic, rapid changes in the Earth’s ice cover. These discoveries have fundamentally altered how scientists view ice-sheet change. Instead of just slow changes in snow accumulation and melting over centuries or millennia, important changes can occur in sudden events lasting only months, weeks, or even a single day. Our understanding of these short time- and space-scale processes, which hold important implications for future global sea level rise, has been impeded by the low temporal and spatial resolution, delayed sensor tasking, incomplete coverage, inaccessibility and/or high cost of data available to investigators. New cross-agency partnerships and data access policies provide the opportunity to dramatically improve the resolution of ice sheet observations by an order of magnitude, from timescales of months and distances of 10’s of meters, to days and meters or less. Advances in image processing technology also enable application of currently under-utilized datasets. The infrastructure for systematically gathering, processing, analyzing and distributing these data does not currently exist. Here we present the development of a multi-institutional, multi-platform observatory for rapid ice change with the ultimate objective of helping to elucidate the relevant timescales and processes of ice sheet dynamics and response to climate change. The Rapid Ice Sheet Observatory (RISCO) gathers observations of short time- and space-scale Cryosphere events and makes them easily accessible to investigators, media and general public. As opposed to existing data centers, which are structured to archive and distribute diverse types of raw data to end users with the specialized software and skills to analyze them, RISCO focuses on three types of geo-referenced raster (image) data products in a format immediately viewable with commonly available software. These three products are (1) sequences of images

  4. The paradox of IDs: an account of an ethnographic experience in the US

    Directory of Open Access Journals (Sweden)

    Mariza Peirano

    2008-01-01

    Full Text Available In the modern world, IDs are indispensable objects, without which we cannot prove that we are who we say we are. We need material substantiation that attests to the authenticity of our self-identification. This paper is an account of an ethnographic experience about IDs and identification processes in the US, based on the examination of two events in which Eliot Spitzer, the New York State governor from January 2007 to March 2008, was a central figure. A comparison with the Brazilian scenario is present throughout the paper, and it ends by focusing on the ID theft phenomenon.

  5. Electricity and gas market observatory. 2. Quarter 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The purpose of the observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This observatory is updated every three months and data are available on CRE web site (www.cre.fr). The present observatory is dedicated only to eligible customers before 1 July 2007, i.e. non-residential customers. Statistics related to residential customers will be published in the next observatory (1 December 2007). Content: A - The electricity market: The retail electricity market (Introduction, Non-residential customer segments and their respective weights, Status at July 1, 2007, Dynamic analysis: 2. Quarter 2007); The wholesale electricity market (Introduction, Wholesale market activity in France, Wholesale market activity in France, Prices on the French wholesale market and European comparison, Import and export volumes, Concentration of the French electricity market, Striking fact of the second quarter 2007); B - The gas market: The retail gas market (Introduction, The non-residential customer segments and their respective weights, Status at July 1, 2007); The wholesale gas market (Gas pricing and gas markets in Europe, The wholesale market in France); C - Appendices: Electricity and gas market observatories combined glossary, Specific electricity market observatory glossary, Specific gas market observatory glossary

  6. Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

    Science.gov (United States)

    Sidorov, Roman; Soloviev, Anatoly; Krasnoperov, Roman; Kudin, Dmitry; Grudnev, Andrei; Kopytenko, Yury; Kotikov, Andrei; Sergushin, Pavel

    2017-11-01

    Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS) - the Geophysical Center of RAS (GC RAS) and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb). On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG) for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

  7. Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

    Directory of Open Access Journals (Sweden)

    R. Sidorov

    2017-11-01

    Full Text Available Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS – the Geophysical Center of RAS (GC RAS and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb. On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

  8. TWO EXOPLANETS DISCOVERED AT KECK OBSERVATORY

    International Nuclear Information System (INIS)

    Valenti, Jeff A.; Fischer, Debra; Giguere, Matt; Isaacson, Howard; Marcy, Geoffrey W.; Howard, Andrew W.; Johnson, John A.; Henry, Gregory W.; Wright, Jason T.

    2009-01-01

    We present two exoplanets detected at Keck Observatory. HD 179079 is a G5 subgiant that hosts a hot Neptune planet with M sin i = 27.5 M + in a 14.48 days, low-eccentricity orbit. The stellar reflex velocity induced by this planet has a semiamplitude of K = 6.6 m s -1 . HD 73534 is a G5 subgiant with a Jupiter-like planet of M sin i = 1.1 M Jup and K = 16 m s -1 in a nearly circular 4.85 yr orbit. Both stars are chromospherically inactive and metal-rich. We discuss a known, classical bias in measuring eccentricities for orbits with velocity semiamplitudes, K, comparable to the radial velocity uncertainties. For exoplanets with periods longer than 10 days, the observed exoplanet eccentricity distribution is nearly flat for large amplitude systems (K > 80 m s -1 ), but rises linearly toward low eccentricity for lower amplitude systems (K > 20 m s -1 ).

  9. The CARIBIC flying observatory and its applications

    International Nuclear Information System (INIS)

    Brenninkmeijer, C.

    2012-01-01

    The troposphere can be considered as a complex chemical reactor reaching from the boundary layer up to the tropopause region, in which a multitude of reactions takes place driven by sunlight and supplied with precursors emitted by vegetation, wildfires, and obviously human activities on earth, like burning oil products. Research aircraft (say modified business jets) are far too expensive for a global view of this extensive atmospheric system that changes from day to night, season to season, year to year, and will keep changing. CARIBIC (www.caribic.de) is a logical answer; it is a flying observatory, a 1.5 ton freight container packed with over 15 instruments, for exploring the atmosphere on a regular basis using cargo space in a Lufthansa Airbus A340-600 on intercontinental flights. By means of various results obtained by CARIBIC, about among others volcanic eruptions, the monsoon and accompanying emissions of methane, and long range transport of pollution, we will show how some of the questions atmospheric research grapples with are being addressed, without having a fleet of business jets. (author)

  10. Distributed Computing for the Pierre Auger Observatory

    International Nuclear Information System (INIS)

    Chudoba, J.

    2015-01-01

    Pierre Auger Observatory operates the largest system of detectors for ultra-high energy cosmic ray measurements. Comparison of theoretical models of interactions with recorded data requires thousands of computing cores for Monte Carlo simulations. Since 2007 distributed resources connected via EGI grid are successfully used. The first and the second versions of production system based on bash scripts and MySQL database were able to submit jobs to all reliable sites supporting Virtual Organization auger. For many years VO auger belongs to top ten of EGI users based on the total used computing time. Migration of the production system to DIRAC interware started in 2014. Pilot jobs improve efficiency of computing jobs and eliminate problems with small and less reliable sites used for the bulk production. The new system has also possibility to use available resources in clouds. Dirac File Catalog replaced LFC for new files, which are organized in datasets defined via metadata. CVMFS is used for software distribution since 2014. In the presentation we give a comparison of the old and the new production system and report the experience on migrating to the new system. (paper)

  11. Table mountain observatory support to other programs

    International Nuclear Information System (INIS)

    Harris, A.W.

    1988-01-01

    The Table Mountain Observatory (TMO) facilities include well equipped 24 inch and 16 inch telescopes with a 40 inch telescope (owned by Pomona College) due for completion during FY 89. This proposal is to provide operational support (equipment maintenance, setup, and observing assistnce) at TMO to other programs. The program currently most heavily supported by this grant is the asteroid photometry program directed by A. W. Harris. During 1987, about 20 asteroids were observed, including a near-earth asteroid, 1951 Midas. The photometric observations are used to derive rotation periods, estimate shapes and pole orientations, and to define the phase relations of asteroids. The E class asteroid 64 Angelina was observed, and showed the same opposition spike observed of 44 Jysa, last year. Comet observations are made with the narrow band camera system of David Rees, University College London. Observational support and training was provided to students and faculty from Claremont Colleges for variable star observing programs. Researchers propose to continue the asteroid program, with emphasis on measuring phase relations of low and high albedo asteroids at very low phase angles, and supporting collaborative studies of asteroid shapes

  12. Neutrino observations from the Sudbury Neutrino Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, Q.R.; Allen, R.C.; Andersen, T.C.; Anglin, J.D.; Barton,J.C.; Beier, E.W.; Bercovitch, M.; Bigu, J.; Biller, S.D.; Black, R.A.; Blevis, I.; Boardman, R.J.; Boger, J.; Bonvin, E.; Boulay, M.G.; Bowler,M.G.; Bowles, T.J.; Brice, S.J.; Browne, M.C.; Bullard, T.V.; Buhler, G.; Cameron, J.; Chan, Y.D.; Chen, H.H.; Chen, M.; Chen, X.; Cleveland, B.T.; Clifford, E.T.H.; Cowan, J.H.M.; Cowen, D.F.; Cox, G.A.; Dai, X.; Dalnoki-Veress, F.; Davidson, W.F.; Doe, P.J.; Doucas, G.; Dragowsky,M.R.; Duba, C.A.; Duncan, F.A.; Dunford, M.; Dunmore, J.A.; Earle, E.D.; Elliott, S.R.; Evans, H.C.; Ewan, G.T.; Farine, J.; Fergani, H.; Ferraris, A.P.; Ford, R.J.; Formaggio, J.A.; Fowler, M.M.; Frame, K.; Frank, E.D.; Frati, W.; Gagnon, N.; Germani, J.V.; Gil, S.; Graham, K.; Grant, D.R.; Hahn, R.L.; Hallin, A.L.; Hallman, E.D.; Hamer, A.S.; Hamian, A.A.; Handler, W.B.; Haq, R.U.; Hargrove, C.K.; Harvey, P.J.; Hazama, R.; Heeger, K.M.; Heintzelman, W.J.; Heise, J.; Helmer, R.L.; Hepburn, J.D.; Heron, H.; Hewett, J.; Hime, A.; Hykawy, J.G.; Isaac,M.C.P.; Jagam, P.; Jelley, N.A.; Jillings, C.; Jonkmans, G.; Kazkaz, K.; Keener, P.T.; Klein, J.R.; Knox, A.B.; Komar, R.J.; Kouzes, R.; Kutter,T.; Kyba, C.C.M.; Law, J.; Lawson, I.T.; Lay, M.; Lee, H.W.; Lesko, K.T.; Leslie, J.R.; Levine, I.; Locke, W.; Luoma, S.; Lyon, J.; Majerus, S.; Mak, H.B.; Maneira, J.; Manor, J.; Marino, A.D.; McCauley, N.; McDonald,D.S.; McDonald, A.B.; McFarlane, K.; McGregor, G.; Meijer, R.; Mifflin,C.; Miller, G.G.; Milton, G.; Moffat, B.A.; Moorhead, M.; Nally, C.W.; Neubauer, M.S.; Newcomer, F.M.; Ng, H.S.; Noble, A.J.; Norman, E.B.; Novikov, V.M.; O' Neill, M.; Okada, C.E.; Ollerhead, R.W.; Omori, M.; Orrell, J.L.; Oser, S.M.; Poon, A.W.P.; Radcliffe, T.J.; Roberge, A.; Robertson, B.C.; Robertson, R.G.H.; Rosendahl, S.S.E.; Rowley, J.K.; Rusu, V.L.; Saettler, E.; Schaffer, K.K.; Schwendener,M.H.; Schulke, A.; Seifert, H.; Shatkay, M.; Simpson, J.J.; Sims, C.J.; et al.

    2001-09-24

    The Sudbury Neutrino Observatory (SNO) is a water imaging Cherenkov detector. Its usage of 1000 metric tons of D{sub 2}O as target allows the SNO detector to make a solar-model independent test of the neutrino oscillation hypothesis by simultaneously measuring the solar {nu}{sub e} flux and the total flux of all active neutrino species. Solar neutrinos from the decay of {sup 8}B have been detected at SNO by the charged-current (CC) interaction on the deuteron and by the elastic scattering (ES) of electrons. While the CC reaction is sensitive exclusively to {nu}{sub e}, the ES reaction also has a small sensitivity to {nu}{sub {mu}} and {nu}{sub {tau}}. In this paper, recent solar neutrino results from the SNO experiment are presented. It is demonstrated that the solar flux from {sup 8}B decay as measured from the ES reaction rate under the no-oscillation assumption is consistent with the high precision ES measurement by the Super-Kamiokande experiment. The {nu}{sub e} flux deduced from the CC reaction rate in SNO differs from the Super-Kamiokande ES results by 3.3{sigma}. This is evidence for an active neutrino component, in additional to {nu}{sub e}, in the solar neutrino flux. These results also allow the first experimental determination of the total active {sup 8}B neutrino flux from the Sun, and is found to be in good agreement with solar model predictions.

  13. Recent results from the Pierre Auger Observatory

    International Nuclear Information System (INIS)

    Gouffon, Philippe

    2010-01-01

    Full text. The Pierre Auger Observatory has been designed to observe cosmic rays with energies above 1018 eV . The southern site, located in Malargue, Argentina, is now fully operational (since mid 2008) and has been collecting data continuously while being deployed. The northern site, which will give a full sky coverage, is under development in Lamar, Colorado, USA. The PAO uses two complementary techniques to measure the direction of arrival and the energy of the comic rays. In the southern site, its 1600 water Cerenkov tanks, spread over 3000 km 2 , sample the extended air shower front when it hits the ground, measuring time and energy deposited, while the 4 fluorescence detectors stations, each with 6 telescopes, collect the UV light emitted by the shower core, registering the time, intensity and angle of reception. Though the Pierre Auger collaboration will be taking data for the next two decades, several results have already been published based on data collected until 2009 and will be discussed briefly: the energy spectrum and its implications on the GZK cut off controversy, limits on photon and neutrino fluxes, anisotropy, point sources and mass composition. (author)

  14. The upgrade of the HAWC observatory

    Energy Technology Data Exchange (ETDEWEB)

    Schoorlemmer, Harm [Max-Plank-Institut fuer Kernphysik, Heidelberg (Germany); Collaboration: HAWC-Collaboration

    2016-07-01

    The High Altitude Water Cherenkov (HAWC) high-energy gamma-ray observatory has recently been completed near the Sierra Negra volcano in central Mexico. HAWC consists of 300 Water Cherenkov Detectors, each containing 200 tons of purified water, that cover a total surface area of 20,000 m{sup 2}. HAWC observes gamma rays in the 0.1-100 TeV range and has a sensitivity to TeV-scale gamma-ray sources an order of magnitude better than previous air-shower arrays. The HAWC trigger for the highest energy gamma rays reaches an effective area of 10{sup 5} m{sup 2} but many of them are poorly reconstructed because the shower core falls outside the array. An upgrade that increases the present fraction of well reconstructed showers above 10 TeV by a factor of 3-4 can be done with a sparse outrigger array of small water Cherenkov detectors that pinpoint the core position and by that improve the angular resolution of the reconstructed showers. Such an outrigger array would be of the order of 300 small water Cherenkov detectors of 2.5 m{sup 3} placed over an area four times larger than HAWC. The Max Planck Institute fuer Kernphysik in Heidelberg just joined the collaboration and will provide the FADC electronics for the readout of the outrigger tanks. Detailed simulations are being performed to optimize the performance of the upgrade.

  15. Distributed Computing for the Pierre Auger Observatory

    Science.gov (United States)

    Chudoba, J.

    2015-12-01

    Pierre Auger Observatory operates the largest system of detectors for ultra-high energy cosmic ray measurements. Comparison of theoretical models of interactions with recorded data requires thousands of computing cores for Monte Carlo simulations. Since 2007 distributed resources connected via EGI grid are successfully used. The first and the second versions of production system based on bash scripts and MySQL database were able to submit jobs to all reliable sites supporting Virtual Organization auger. For many years VO auger belongs to top ten of EGI users based on the total used computing time. Migration of the production system to DIRAC interware started in 2014. Pilot jobs improve efficiency of computing jobs and eliminate problems with small and less reliable sites used for the bulk production. The new system has also possibility to use available resources in clouds. Dirac File Catalog replaced LFC for new files, which are organized in datasets defined via metadata. CVMFS is used for software distribution since 2014. In the presentation we give a comparison of the old and the new production system and report the experience on migrating to the new system.

  16. Recent results from the Pierre Auger Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Gouffon, Philippe [Universidade de Sao Paulo (IF/USP), SP (Brazil). Inst. de Fisica

    2010-07-01

    Full text. The Pierre Auger Observatory has been designed to observe cosmic rays with energies above 1018 eV . The southern site, located in Malargue, Argentina, is now fully operational (since mid 2008) and has been collecting data continuously while being deployed. The northern site, which will give a full sky coverage, is under development in Lamar, Colorado, USA. The PAO uses two complementary techniques to measure the direction of arrival and the energy of the comic rays. In the southern site, its 1600 water Cerenkov tanks, spread over 3000 km{sup 2}, sample the extended air shower front when it hits the ground, measuring time and energy deposited, while the 4 fluorescence detectors stations, each with 6 telescopes, collect the UV light emitted by the shower core, registering the time, intensity and angle of reception. Though the Pierre Auger collaboration will be taking data for the next two decades, several results have already been published based on data collected until 2009 and will be discussed briefly: the energy spectrum and its implications on the GZK cut off controversy, limits on photon and neutrino fluxes, anisotropy, point sources and mass composition. (author)

  17. Neutrino Observations from the Sudbury Neutrino Observatory

    Science.gov (United States)

    Q. R. Ahmad, R. C. Allen, T. C. Andersen, J. D. Anglin, G. B?hler, J. C. Barton, E. W. Beier, M. Bercovitch, J. Bigu, S. Biller, R. A. Black, I. Blevis, R. J. Boardman, J. Boger, E. Bonvin, M. G. Boulay, M. G. Bowler, T. J. Bowles, S. J. Brice, M. C. Browne, T. V. Bullard, T. H. Burritt, K. Cameron, J. Cameron, Y. D. Chan, M. Chen, H. H. Chen, X. Chen, M. C. Chon, B. T. Cleveland, E. T. H. Clifford, J. H. M. Cowan, D. F. Cowen, G. A. Cox, Y. Dai, X. Dai, F. Dalnoki-Veress, W. F. Davidson, P. J. Doe, G. Doucas, M. R. Dragowsky, C. A. Duba, F. A. Duncan, J. Dunmore, E. D. Earle, S. R. Elliott, H. C. Evans, G. T. Ewan, J. Farine, H. Fergani, A. P. Ferraris, R. J. Ford, M. M. Fowler, K. Frame, E. D. Frank, W. Frati, J. V. Germani, S. Gil, A. Goldschmidt, D. R. Grant, R. L. Hahn, A. L. Hallin, E. D. Hallman, A. Hamer, A. A. Hamian, R. U. Haq, C. K. Hargrove, P. J. Harvey, R. Hazama, R. Heaton, K. M. Heeger, W. J. Heintzelman, J. Heise, R. L. Helmer, J. D. Hepburn, H. Heron, J. Hewett, A. Hime, M. Howe, J. G. Hykawy, M. C. P. Isaac, P. Jagam, N. A. Jelley, C. Jillings, G. Jonkmans, J. Karn, P. T. Keener, K. Kirch, J. R. Klein, A. B. Knox, R. J. Komar, R. Kouzes, T. Kutter, C. C. M. Kyba, J. Law, I. T. Lawson, M. Lay, H. W. Lee, K. T. Lesko, J. R. Leslie, I. Levine, W. Locke, M. M. Lowry, S. Luoma, J. Lyon, S. Majerus, H. B. Mak, A. D. Marino, N. McCauley, A. B. McDonald, D. S. McDonald, K. McFarlane, G. McGregor, W. McLatchie, R. Meijer Drees, H. Mes, C. Mifflin, G. G. Miller, G. Milton, B. A. Moffat, M. Moorhead, C. W. Nally, M. S. Neubauer, F. M. Newcomer, H. S. Ng, A. J. Noble, E. B. Norman, V. M. Novikov, M. O'Neill, C. E. Okada, R. W. Ollerhead, M. Omori, J. L. Orrell, S. M. Oser, A. W. P. Poon, T. J. Radcliffe, A. Roberge, B. C. Robertson, R. G. H. Robertson, J. K. Rowley, V. L. Rusu, E. Saettler, K. K. Schaffer, A. Schuelke, M. H. Schwendener, H. Seifert, M. Shatkay, J. J. Simpson, D. Sinclair, P. Skensved, A. R. Smith, M. W. E. Smith, N. Starinsky, T. D. Steiger, R. G. Stokstad, R. S. Storey, B. Sur, R. Tafirout, N. Tagg, N. W. Tanner, R. K. Taplin, M. Thorman, P. Thornewell, P. T. Trent, Y. I. Tserkovnyak, R. Van Berg, R. G. Van de Water, C. J. Virtue, C. E. Waltham, J.-X. Wang, D. L. Wark, N. West, J. B. Wilhelmy, J. F. Wilkerson, J. Wilson, P. Wittich, J. M. Wouters, and M. Yeh

    2001-09-24

    The Sudbury Neutrino Observatory (SNO) is a water imaging Cherenkov detector. Its usage of 1000 metric tons of D{sub 2}O as target allows the SNO detector to make a solar-model independent test of the neutrino oscillation hypothesis by simultaneously measuring the solar {nu}{sub e} flux and the total flux of all active neutrino species. Solar neutrinos from the decay of {sup 8}B have been detected at SNO by the charged-current (CC) interaction on the deuteron and by the elastic scattering (ES) of electrons. While the CC reaction is sensitive exclusively to {nu}{sub e}, the ES reaction also has a small sensitivity to {nu}{sub {mu}} and {nu}{sub {tau}}. In this paper, recent solar neutrino results from the SNO experiment are presented. It is demonstrated that the solar flux from {sup 8}B decay as measured from the ES reaction rate under the no-oscillation assumption is consistent with the high precision ES measurement by the Super-Kamiokande experiment. The {nu}{sub e} flux deduced from the CC reaction rate in SNO differs from the Super-Kamiokande ES results by 3.3{sigma}. This is evidence for an active neutrino component, in additional to {nu}{sub e}, in the solar neutrino flux. These results also allow the first experimental determination of the total active {sup 8}B neutrino flux from the Sun, and is found to be in good agreement with solar model predictions.

  18. The Importance of Marine Observatories and of RAIA in Particular

    Directory of Open Access Journals (Sweden)

    Luísa Bastos

    2016-08-01

    Full Text Available Coastal and Oceanic Observatories are important tools to provide information on ocean state, phenomena and processes. They meet the need for a better understanding of coastal and ocean dynamics, revealing regional characteristics and vulnerabilities. These observatories are extremely useful to guide human actions in response to natural events and potential climate change impacts, anticipating the occurrence of extreme weather and oceanic events and helping to minimize consequent personal and material damages and costs.International organizations and local governments have shown an increasing interest in operational oceanography and coastal, marine and oceanic observations, which resulted in substantial investments in these areas. A variety of physical, chemical and biological data have been collected to better understand the specific characteristics of each ocean area and its importance in the global context. Also the general public’s interest in marine issues and observatories has been raised, mainly in relation to vulnerability, sustainability and climate change issues. Data and products obtained by an observatory are hence useful to a broad range of stakeholders, from national and local authorities to the population in general.An introduction to Ocean Observatories, including their national and regional importance, and a brief analysis of the societal interest in these observatories and related issues are presented. The potential of a Coastal and Ocean Observatory is then demonstrated using the RAIA observatory as example. This modern and comprehensive observatory is dedicated to improve operational oceanography, technology and marine science for the North Western Iberian coast, and to provide services to a large range of stakeholders.

  19. Id-1 gene and gene products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    Science.gov (United States)

    Desprez, Pierre-Yves; Campisi, Judith

    2014-08-19

    A method for treatment of breast cancer and other types of cancer. The method comprises targeting and modulating Id-1 gene expression, if any, for the Id-1 gene, or gene products in breast or other epithelial cancers in a patient by delivering products that modulate Id-1 gene expression. When expressed, Id-1 gene is a prognostic indicator that cancer cells are invasive and metastatic.

  20. The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

    International Nuclear Information System (INIS)

    Kurooka, Hisanori; Sugai, Manabu; Mori, Kentaro; Yokota, Yoshifumi

    2013-01-01

    Highlights: •Sodium arsenite induces cytoplasmic accumulation of Id3. •Arsenite binds to closely spaced N-terminal cysteine residues of Id3. •N-terminal cysteines are essential for arsenite-induced nuclear export of Id3. •Nuclear export of Id3 counteracts its transcriptional repression activity. -- Abstract: Ids are versatile transcriptional repressors that regulate cell proliferation and differentiation, and appropriate subcellular localization of the Id proteins is important for their functions. We previously identified distinct functional nuclear export signals (NESs) in Id1 and Id2, but no active NES has been reported in Id3. In this study, we found that treatment with the stress-inducing metalloid arsenite led to the accumulation of GFP-tagged Id3 in the cytoplasm. Cytoplasmic accumulation was impaired by a mutation in the Id3 NES-like sequence resembling the Id1 NES, located at the end of the HLH domain. It was also blocked by co-treatment with the CRM1-specific nuclear export inhibitor leptomycin B (LMB), but not with the inhibitors for mitogen-activated protein kinases (MAPKs). Importantly, we showed that the closely spaced N-terminal cysteine residues of Id3 interacted with the arsenic derivative phenylarsine oxide (PAO) and were essential for the arsenite-induced cytoplasmic accumulation, suggesting that arsenite induces the CRM1-dependent nuclear export of Id3 via binding to the N-terminal cysteines. Finally, we demonstrated that Id3 significantly repressed arsenite-stimulated transcription of the immediate-early gene Egr-1 and that this repression activity was inversely correlated with the arsenite-induced nuclear export. Our results imply that Id3 may be involved in the biological action of arsenite

  1. Pengaruh Customer Satisfaction Terhadap Switching Barrier Dan Customer Retention (Survei Pada Mahasiswa Fakultas Ilmu Administrasi Bisnis Angkatan 2012-2013 Universitas Brawijaya Yang Pernah Melakukan Pembelian Di Mcdonald's Malang)

    OpenAIRE

    Kumalasari, Indah

    2013-01-01

    The purpose of this study is to analyze and explain the effect Customer Satisfaction of the switching barrier and Customer Retention. Type of research is explanatory research with survey methods. Sampling technique using probability sampling with simple random sampling. The population in this study is a student of the Faculty of Business Administration Forces 2012-2013 UB ever make purchases at McDonald's Malang and obtained sample was 102 respondents using Machin formula. This study uses de...

  2. Vliv kulturních odlišností a specifik na marketingovou strategii firmy McDonald's - srovnání ČR a USA

    OpenAIRE

    Plesníková, Tereza

    2012-01-01

    The Bachelor's Thesis is focused on cultural and business practices of the United States of America and the Czech Republic. The main goal is to thoroughly examine all the differences in the mentality of these nations using Hofstede's cultural dimensions, and then illustrate these findings on the implementation of marketing and business strategy of McDonald's company. The thesis is concluded by specific examples of marketing and sales campaigns that took place in these two regions.

  3. Astronomical Observatory of Belgrade from 1924 to 1955

    Science.gov (United States)

    Radovanac, M.

    2014-12-01

    History of the Astronomical Observatory in Belgrade, as the presentation is done here, become the field of interest to the author of the present monograph in early 2002. Then, together with Luka C. Popovic, during the Conference "Development of Astronomy among Serbs II" held in early April of that year, he prepared a paper entitled "Astronomska opservatorija tokom Drugog Svetskog rata" (Astronomical Observatory in the Second World War). This paper was based on the archives material concerning the Astronomical Observatory which has been professionally bearing in mind the author's position the subject of his work.

  4. The First Astronomical Observatory in Cluj-Napoca

    Science.gov (United States)

    Szenkovits, Ferenc

    2008-09-01

    One of the most important cities of Romania is Cluj-Napoca (Kolozsvár, Klausenburg). This is a traditional center of education, with many universities and high schools. From the second half of the 18th century the University of Cluj has its own Astronomical Observatory, serving for didactical activities and scientific researches. The famous astronomer Maximillian Hell was one of those Jesuits who put the base of this Astronomical Observatory. Our purpose is to offer a short history of the beginnings of this Astronomical Observatory.

  5. Astronomy and astrophysics communication in the UCM Observatory

    Science.gov (United States)

    Crespo-Chacón, I.; de Castro, E.; Díaz, C.; Gallego, J.; Gálvez, M. C.; Hernán-Obispo, M.; López-Santiago, J.; Montes, D.; Pascual, S.; Verdet, A.; Villar, V.; Zamorano, J.

    We present a summary of the last activities of science communication that have taken place in the Observatorio de la Universidad Complutense de Madrid (UCM Observatory) on the occasion of the Third Science Week of the Comunidad Autónoma de Madrid (3-16 November 2003), including guided tours through the observatory facilities, solar observations, and several talks. Moreover the current telescopes, instruments and tools of the UCM Observatory have allowed us to organize other communicating activities such as the live observation, together with its internet broadcast, of total lunar eclipses and other exceptional astronomical events as the Venus transit that took place in 8 June 2004.

  6. How to save distressed IDS-physician marriages: a case study.

    Science.gov (United States)

    Collins, H; Johnson, B A

    1998-04-01

    A hospital-driven IDS that encounters serious problems resulting from ownership of a physician practice should address those problems by focusing on three core areas: vision and leadership, effectiveness of operations, and physician compensation arrangements. If changes in these areas do not lead to improvements, the IDS may need to consider organizational restructuring. In one case study, a hospital-driven IDS faced the problem of owning a poorly performing MSO with a captive physician group. The IDS's governing board determined that the organization lacked effective communication with the physicians and that realization of the organization's vision would require greater physician involvement in organizational decision making. The organization is expected to undergo some corporate reorganization in which physicians will acquire an equity interest in the enterprise.

  7. Toward operation of series IDs at BL43LXU of SPring-8

    Energy Technology Data Exchange (ETDEWEB)

    Baron, A. Q. R.; Tanaka, T.; Soutome, K.; Takao, M.; Nakamura, T.; Kobayashi, K.; Fujita, T.; Takahashi, S.; Aoyagi, H.; Shimosaki, Y.; Seike, T.; Uchiyama, H.; Ishikawa, D.; Chuang, T.-H.; Kimura, H.; Tanaka, H.; Kitamura, H.; Ishikawa, T. [SPring-8, 1-1-1 Kouto, Sayo, Hyogo, 679 (Japan)

    2016-07-27

    This paper discusses two issues relating to using 3 small gap insertion devices in series at BL43LXU of SPring-8 to make a uniquely powerful source in the 15-26 keV region of the x-ray spectrum. The issues discussed are (1) damage to the covers of the downstream IDs by radiation from the upstream IDs and (2) proper steering of the electron beam to get the best photon beam properties. After tests in several configurations, including one where an ID was run without an impedance-reducing cover, the damage issue was solved by installing a distributed absorber in the most downstream ID. The steering issues were mostly resolved by the introduction of appropriate corrector magnets and feedback. The paper is written from the viewpoint of an interested beamline scientist impressed with the cooperation of different groups to make a source for new science possible.

  8. Pätid võtsid varastatud ID-kaardiga kiirlaene / Põim Kama

    Index Scriptorium Estoniae

    Kama, Põim, 1985-

    2008-01-01

    ID-kaardi vargusega seotud pettusjuhtumist ning jaanuaris jõustunud rahapesu ja terrorismi rahastamise tõkestamise seaduse sättest, mis kohustab laenufirmasid esimese tehingu sooritamisel kliendiga silmast silma kohtuma. Lisatud: kiirlaenufirmad vilistavad seadusele

  9. idSpace Tooling and Training for collaborative distributed product innovation

    NARCIS (Netherlands)

    Rutjens, Marjo; Bitter-Rijpkema, Marlies; Grube, Pascal; Heider, Thomas

    2009-01-01

    Rutjens, M., Bitter-Rijpkema, M., Grube, P. P., & Heider, T. (2009). idSpace Tooling and Training for collaborative distributed product innovation. Workshop during the e-Learning Baltic conference. June, 17-19, 2009, Rostock, Germany.

  10. Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression

    International Nuclear Information System (INIS)

    Zhang, Long; Shi, Songting; Zhang, Juan; Zhou, Fangfang; Dijke, Peter ten

    2012-01-01

    Highlights: ► Expression of Id3 but not Id1 is induced by Wnt3a stimulation in C2C12 cells. ► Wnt3a induces Id3 expression via canonical Wnt/β-catenin pathway. ► Wnt3a-induced Id3 expression does not depend on BMP signaling activation. ► Induction of Id3 expression is critical determinant in Wnt3a-induced cell proliferation and differentiation. -- Abstract: Canonical Wnt signaling plays important roles in regulating cell proliferation and differentiation. In this study, we report that inhibitor of differentiation (Id)3 is a Wnt-inducible gene in mouse C2C12 myoblasts. Wnt3a induced Id3 expression in a β-catenin-dependent manner. Bone morphogenetic protein (BMP) also potently induced Id3 expression. However, Wnt-induced Id3 expression occurred independent of the BMP/Smad pathway. Functional studies showed that Id3 depletion in C2C12 cells impaired Wnt3a-induced cell proliferation and alkaline phosphatase activity, an early marker of osteoblast cells. Id3 depletion elevated myogenin induction during myogenic differentiation and partially impaired Wnt3a suppressed myogenin expression in C2C12 cells. These results suggest that Id3 is an important Wnt/β-catenin induced gene in myoblast cell fate determination.

  11. Uzņēmuma McDonalds konkurētspējas novērtēšanas un tās uzlabošanas iespējas

    OpenAIRE

    Artemjeva, Anžela

    2012-01-01

    Bakalaura darba tēma – „Uzņēmuma McDonalds konkurētspējas novērtēšana un tās uzlabošanas iespējas”. Bakalaura darba mērķis-pamatojoties uz teorētiskām atziņām par konkurenci un konkurētspēju, izpētīt SIA McDonalds konkurētspēju tirgū un tās pilnveidošanas iespējas balstoties uz Latvijas, Lietuvas un Igaunijas investīciju nozares analīzes datu rezultātiem, izdarīt secinājumus un sniegt priekšlikumus SIA McDonalds konkurētspējas uzlabošanai. Bakalaura darba izstrādes gaitā autore ir izstr...

  12. Evaluation of the Micro-ID system for the identification of Yersinia pestis.

    OpenAIRE

    Harrison, D N; Williams, J E

    1985-01-01

    One hundred isolates of Yersinia pestis identified by conventional means were tested by the Micro-ID system to assess its reliability for distinguishing Y. pestis from other members of the family Enterobacteriaceae. The Micro-ID system gave Y. pestis as a choice for the identification of 89 of these cultures, although not always as the first choice. Most nitrate-negative strains of Y. pestis keyed out with Yersinia pseudotuberculosis as first choice and Y. pestis as second or fourth choice.

  13. ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy

    DEFF Research Database (Denmark)

    Rai, Taranjit Singh; Dhandapany, Perundurai Subramaniam; Ahluwalia, Tarun Veer Singh

    2008-01-01

    The study was carried to determine the association of angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with the risk of hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and restrictive cardiomyopathy (RCM).......The study was carried to determine the association of angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with the risk of hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and restrictive cardiomyopathy (RCM)....

  14. Thousands and thousands of kilowatt-hours saved: Results from The Energy Efficiency McDonalds (TEEM) demonstration project in Bay Point, California

    Energy Technology Data Exchange (ETDEWEB)

    Allen, T.; Young, R.; Spata, T.; Smith, V.

    1998-07-01

    Food service operations use more energy per square foot than any other commercial buildings and yet, the opportunity to build energy efficient restaurants is often overlooked due to a lack of information and education within the industry. To meet this challenge and stimulate energy-efficient restaurant design, McDonald's Corporation, the nation's largest restaurant chain, and Pacific Gas and Electric (PG and E), one of the largest combined fuel utilities, are working together in a program called The Energy Efficient McDonald's, or TEEM. TEEM will identify, demonstrate and evaluate energy-saving technologies with the goal of integrating cost-effective energy-efficient technologies into McDonalds universal building specification and giving existing store operators the opportunity to improve their operations. Technologies installed at the TEEM store in Bay Point include: direct evaporative cooler, evaporative precooler, high-efficiency air conditioners, high-efficiency and two-speed exhaust fans, advanced glazing systems, tubular skylights, low-cost dimming controller and electronic ballasts, T-8 fluorescent fixtures. low-temperature occupance sensors for walking cooler/freezer, and an energy management system. An extensive data collection system has been collecting data since the store opened in June 1996. This paper will present the performance results of the energy efficient measures installed using measured data analysis techniques.

  15. Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study.

    Science.gov (United States)

    Filippi, Massimo; Preziosa, Paolo; Meani, Alessandro; Ciccarelli, Olga; Mesaros, Sarlota; Rovira, Alex; Frederiksen, Jette; Enzinger, Christian; Barkhof, Frederik; Gasperini, Claudio; Brownlee, Wallace; Drulovic, Jelena; Montalban, Xavier; Cramer, Stig P; Pichler, Alexander; Hagens, Marloes; Ruggieri, Serena; Martinelli, Vittorio; Miszkiel, Katherine; Tintorè, Mar; Comi, Giancarlo; Dekker, Iris; Uitdehaag, Bernard; Dujmovic-Basuroski, Irena; Rocca, Maria A

    2018-02-01

    In 2016, the Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) network proposed modifications to the MRI criteria to define dissemination in space (DIS) and time (DIT) for the diagnosis of multiple sclerosis in patients with clinically isolated syndrome (CIS). Changes to the DIS definition included removal of the distinction between symptomatic and asymptomatic lesions, increasing the number of lesions needed to define periventricular involvement to three, combining cortical and juxtacortical lesions, and inclusion of optic nerve evaluation. For DIT, removal of the distinction between symptomatic and asymptomatic lesions was suggested. We compared the performance of the 2010 McDonald and 2016 MAGNIMS criteria for multiple sclerosis diagnosis in a large multicentre cohort of patients with CIS to provide evidence to guide revisions of multiple sclerosis diagnostic criteria. Brain and spinal cord MRI and optic nerve assessments from patients with typical CIS suggestive of multiple sclerosis done less than 3 months from clinical onset in eight European multiple sclerosis centres were included in this retrospective study. Eligible patients were 16-60 years, and had a first CIS suggestive of CNS demyelination and typical of relapsing-remitting multiple sclerosis, a complete neurological examination, a baseline brain and spinal cord MRI scan obtained less than 3 months from clinical onset, and a follow-up brain scan obtained less than 12 months from CIS onset. We recorded occurrence of a second clinical attack (clinically definite multiple sclerosis) at months 36 and 60. We evaluated MRI criteria performance for DIS, DIT, and DIS plus DIT with a time-dependent receiver operating characteristic curve analysis. Between June 16, 1995, and Jan 27, 2017, 571 patients with CIS were screened, of whom 368 met all study inclusion criteria. At the last evaluation (median 50·0 months [IQR 27·0-78·4]), 189 (51%) of 368 patients developed clinically definite multiple

  16. A citizens' jury on regulation of McDonald's products and operations in Australia in response to a corporate health impact assessment.

    Science.gov (United States)

    Anaf, Julia; Baum, Fran; Fisher, Matthew

    2018-04-01

    1) To report outcomes from a citizens' jury examining regulatory responses to the health impacts of McDonald's Australia; 2) To determine the value of using citizens' juries to develop policy recommendations based on the findings of health impact assessment of transnational corporations (TNCs). A citizens' jury engaged 15 randomly selected and demographically representative jurors from metropolitan Adelaide to deliberate on the findings of a Corporate Health Impact Assessment, and to decide on appropriate policy actions. Jurors unanimously called for government regulation to ensure that transnational fast food corporations pay taxes on profits in the country of income. A majority (two-thirds) also recommended government regulation to reduce fast food advertising, and improve standards of consumer information including a star-ratings system. A minority held the view that no further regulation is required of the corporate fast food industry in Australia. The jury's recommendations can help inform policy makers about the importance of ending the legal profit-shifting strategies by TNCs that affect taxation revenue. They also endorse regulating the fast food industry to provide healthier food, and employing forms of community education and awareness-raising. Implications for public health: Citizens' juries can play an important role in providing feedback and policy recommendations in response to the findings of a health impact assessment of transnational corporations. © 2018 The Authors.

  17. Virtual Observatories, Data Mining, and Astroinformatics

    Science.gov (United States)

    Borne, Kirk

    The historical, current, and future trends in knowledge discovery from data in astronomy are presented here. The story begins with a brief history of data gathering and data organization. A description of the development ofnew information science technologies for astronomical discovery is then presented. Among these are e-Science and the virtual observatory, with its data discovery, access, display, and integration protocols; astroinformatics and data mining for exploratory data analysis, information extraction, and knowledge discovery from distributed data collections; new sky surveys' databases, including rich multivariate observational parameter sets for large numbers of objects; and the emerging discipline of data-oriented astronomical research, called astroinformatics. Astroinformatics is described as the fourth paradigm of astronomical research, following the three traditional research methodologies: observation, theory, and computation/modeling. Astroinformatics research areas include machine learning, data mining, visualization, statistics, semantic science, and scientific data management.Each of these areas is now an active research discipline, with significantscience-enabling applications in astronomy. Research challenges and sample research scenarios are presented in these areas, in addition to sample algorithms for data-oriented research. These information science technologies enable scientific knowledge discovery from the increasingly large and complex data collections in astronomy. The education and training of the modern astronomy student must consequently include skill development in these areas, whose practitioners have traditionally been limited to applied mathematicians, computer scientists, and statisticians. Modern astronomical researchers must cross these traditional discipline boundaries, thereby borrowing the best of breed methodologies from multiple disciplines. In the era of large sky surveys and numerous large telescopes, the potential

  18. Cyberinfrastructure for the NSF Ocean Observatories Initiative

    Science.gov (United States)

    Orcutt, J. A.; Vernon, F. L.; Arrott, M.; Chave, A.; Krueger, I.; Schofield, O.; Glenn, S.; Peach, C.; Nayak, A.

    2007-12-01

    The Internet today is vastly different than the Internet that we knew even five years ago and the changes that will be evident five years from now, when the NSF Ocean Observatories Initiative (OOI) prototype has been installed, are nearly unpredictable. Much of this progress is based on the exponential growth in capabilities of consumer electronics and information technology; the reality of this exponential behavior is rarely appreciated. For example, the number of transistors on a square cm of silicon will continue to double every 18 months, the density of disk storage will double every year, and network bandwidth will double every eight months. Today's desktop 2TB RAID will be 64TB and the 10Gbps Regional Scale Network fiber optical connection will be running at 1.8Tbps. The same exponential behavior characterizes the future of genome sequencing. The first two sequences of composites of individuals' genes cost tens of millions of dollars in 2001. Dr. Craig Venter just published a more accurate complete human genome (his own) at a cost on the order of 100,000. The J. Craig Venter Institute has provided support for the X Prize for Genomics offering 10M to the first successful sequencing of a human genome for $1,000. It's anticipated that the prize will be won within five years. Major advances in technology that are broadly viewed as disruptive or revolutionary rather than evolutionary will often depend upon the exploitation of exponential expansions in capability. Applications of these ideas to the OOI will be discussed. Specifically, the agile ability to scale cyberinfrastructure commensurate with the exponential growth of sensors, networks and computational capability and demand will be described.

  19. The Science and Design of the AGIS Observatory

    Science.gov (United States)

    Schroedter, Martin

    2010-02-01

    The AGIS observatory is a next-generation array of imaging atmospheric Cherenkov telescopes (IACTs) for gamma-ray astronomy between 100 GeV and 100 TeV. The AGIS observatory is the next logical step in high energy gamma-ray astronomy, offering improved angular resolution and sensitivity compared to FERMI, and overlapping the high energy end of FERMI's sensitivity band. The baseline AGIS observatory will employ an array of 36 Schwarzschild-Couder IACTs in combination with a highly pixelated (0.05^o diameter) camera. The instrument is designed to provide millicrab sensitivity over a wide (8^o diameter) field of view, allowing both deep studies of faint point sources as well as efficient mapping of the Galactic plane and extended sources. I will describe science drivers behind the AGIS observatory and the design and status of the project. )

  20. Science Potential of a Deep Ocean Antineutrino Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Dye, S.T. [Department of Physics and Astronomy, University of Hawaii, 2505 Correa Road, Honolulu, Hawaii, 96822 (United States); College of Natural Sciences, Hawaii Pacific University, 45-045 Kamehameha Highway, Kaneohe, Hawaii 96744 (United States)

    2007-06-15

    This paper presents science potential of a deep ocean antineutrino observatory being developed at Hawaii. The observatory design allows for relocation from one site to another. Positioning the observatory some 60 km distant from a nuclear reactor complex enables precision measurement of neutrino mixing parameters, leading to a determination of neutrino mass hierarchy and {theta}{sub 13}. At a mid-Pacific location the observatory measures the flux and ratio of uranium and thorium decay neutrinos from earth's mantle and performs a sensitive search for a hypothetical natural fission reactor in earth's core. A subsequent deployment at another mid-ocean location would test lateral heterogeneity of uranium and thorium in earth's mantle.

  1. ALOHA Cabled Observatory (ACO): Acoustic Doppler Current Profiler (ADCP): Velocity

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The University of Hawaii's ALOHA ("A Long-term Oligotrophic Habitat Assessment") Cabled Observatory (ACO) is located 100 km north of the island of Oahu, Hawaii (22...

  2. Integration of space geodesy: a US National Geodetic Observatory

    Science.gov (United States)

    Yunck, Thomas P.; Neilan, Ruth

    2003-01-01

    In the interest of improving the performance and efficiency of space geodesy a diverse group in the U.S., in collaboration with IGGOS, has begun to establish a unified National Geodetic Observatory (NGO).

  3. 150th Anniversary of the Astronomical Observatory Library of Sciences

    Science.gov (United States)

    Solntseva, T.

    The scientific library of the Astronomical observatory of Kyiv Taras Shevchenko University is one of the oldest ones of such a type in Ukraine. Our Astronomical Observatory and its scientific library will celebrate 150th anniversary of their foundation. 900 volumes of duplicates of Olbers' private library underlay our library. These ones were acquired by Russian Academy of Sciences for Poulkovo observatory in 1841 but according to Struve's order were transmitted to Kyiv Saint Volodymyr University. These books are of great value. There are works edited during Copernicus', Kepler's, Galilei's, Newton's, Descartes' lifetime. Our library contains more than 100000 units of storage - monographs, periodical astronomical editions from the first (Astronomische Nachrichten, Astronomical journal, Monthly Notices etc.), editions of the majority of the astronomical observatories and institutions of the world, unique astronomical atlases and maps

  4. How Mount Stromlo Observatory shed its imperial beginnings

    Science.gov (United States)

    Bhathal, Ragbir

    2014-12-01

    In the 90 years since its foundation in 1924, Mount Stromlo Observatory in Australia has changed from an outpost of empire to an international research institution. Ragbir Bhathal examines how the British influence waxed and waned.

  5. Experience in CCD Photometry at the Tartu Observatory

    Directory of Open Access Journals (Sweden)

    Tuvikene T.

    2003-12-01

    Full Text Available We give overview of the CCD instrumentation and data reduction techniques used at the Tartu Observatory. The first results from photometric observations of the peculiar variable V838 Mon are presented.

  6. A Regional Observatory for Producers' Climate Change Adaptation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-22

    Apr 22, 2016 ... A Regional Observatory for Producers' Climate Change Adaptation in Thies, Senegal ... The Adaptation Insights series is a joint publication of the International Development Research Centre and the Centre for ... Innovation.

  7. Grain investigation by the help of satellite observatories

    International Nuclear Information System (INIS)

    Friedemann, C.

    1988-01-01

    Interstellar grains are investigated by the help of satellite observatories taking into account extraterrestrical ultraviolet observations, infrared astronomy by the help of orbiting cooled telescopes, observed ultraviolet properties of interstellar grains, and consequences of infrared astronomy for dust investigation

  8. Visualization of Large Amount of Spectra in Virtual Observatory Environment

    Czech Academy of Sciences Publication Activity Database

    Šaloun, P.; Andrešič, D.; Škoda, Petr; Zelinka, I.

    2014-01-01

    Roč. 11, č. 6 (2014), s. 613-620 ISSN 1476-8186 Institutional support: RVO:67985815 Keywords : SPLAT-VO * virtual observatory * spectra Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  9. Astronomy from the Moon and International Lunar Observatory Missions

    Science.gov (United States)

    Durst, S.; Takahashi, Y. D.

    2018-04-01

    Astronomy from the Moon provides a promising new frontier for 21st century astrophysics and related science activity. International Lunar Observatory Association is an enterprise advancing missions to the Moon for observation and communication.

  10. NASA Observatory Confirms Black Hole Limits

    Science.gov (United States)

    2005-02-01

    The very largest black holes reach a certain point and then grow no more, according to the best survey to date of black holes made with NASA's Chandra X-ray Observatory. Scientists have also discovered many previously hidden black holes that are well below their weight limit. These new results corroborate recent theoretical work about how black holes and galaxies grow. The biggest black holes, those with at least 100 million times the mass of the Sun, ate voraciously during the early Universe. Nearly all of them ran out of 'food' billions of years ago and went onto a forced starvation diet. Focus on Black Holes in the Chandra Deep Field North Focus on Black Holes in the Chandra Deep Field North On the other hand, black holes between about 10 and 100 million solar masses followed a more controlled eating plan. Because they took smaller portions of their meals of gas and dust, they continue growing today. "Our data show that some supermassive black holes seem to binge, while others prefer to graze", said Amy Barger of the University of Wisconsin in Madison and the University of Hawaii, lead author of the paper describing the results in the latest issue of The Astronomical Journal (Feb 2005). "We now understand better than ever before how supermassive black holes grow." One revelation is that there is a strong connection between the growth of black holes and the birth of stars. Previously, astronomers had done careful studies of the birthrate of stars in galaxies, but didn't know as much about the black holes at their centers. DSS Optical Image of Lockman Hole DSS Optical Image of Lockman Hole "These galaxies lose material into their central black holes at the same time that they make their stars," said Barger. "So whatever mechanism governs star formation in galaxies also governs black hole growth." Astronomers have made an accurate census of both the biggest, active black holes in the distance, and the relatively smaller, calmer ones closer by. Now, for the first

  11. Id3 induces an Elk-1–caspase-8-dependent apoptotic pathway in squamous carcinoma cells

    International Nuclear Information System (INIS)

    Chen, You-Shin; Aubee, Joseph; DiVito, Kyle A; Zhou, Hengbo; Zhang, Weiyi; Chou, Fen-Pi; Simbulan-Rosenthal, Cynthia M; Rosenthal, Dean S

    2015-01-01

    Inhibitor of differentiation/DNA-binding (Id) proteins are helix–loop–helix (HLH) transcription factors. The Id protein family (Id1–Id4) mediates tissue homeostasis by regulating cellular processes including differentiation, proliferation, and apoptosis. Ids typically function as dominant negative HLH proteins, which bind other HLH proteins and sequester them away from DNA promoter regions. Previously, we have found that Id3 induced apoptosis in immortalized human keratinocytes upon UVB exposure, consistent with its role as a tumor suppressor. To investigate the role of Id3 in malignant squamous cell carcinoma (SCC) cells (A431), a tetracycline-regulated inducible system was used to induce Id3 in cell culture and mouse xenograft models. We found that upon Id3 induction, there was a decrease in cell number under low serum conditions, as well as in soft agar. Microarray, RT-PCR, immunoblot, siRNA, and inhibitor studies revealed that Id3 induced expression of Elk-1, an E-twenty-six (ETS)-domain transcription factor, inducing procaspase-8 expression and activation. Id3 deletion mutants revealed that 80 C-terminal amino acids, including the HLH, are important for Id3-induced apoptosis. In a mouse xenograft model, Id3 induction decreased tumor size by 30%. Using immunofluorescent analysis, we determined that the tumor size decrease was also mediated through apoptosis. Furthermore, we show that Id3 synergizes with 5-FU and cisplatin therapies for nonmelanoma skin cancer cells. Our studies have shown a molecular mechanism by which Id3 induces apoptosis in SCC, and this information can potentially be used to develop new treatments for SCC patients

  12. A New Observatory for Eastern College: A Dream Realized

    Science.gov (United States)

    Bradstreet, D. H.

    1996-12-01

    The Eastern College Observatory began as a rooftop observing deck with one Celestron 8 telescope in 1976 as the workhorse instrument of the observational astronomy lab within the core curriculum. For 20 years the observing deck served as the crude observatory, being augmented through the years by other computerized Celestron 8's and a 17.5" diameter Dobsonian with computerized setting circles. The lab consisted primarily of visual observations and astrophotography. In 1987 plans were set into motion to raise money to build a permanent Observatory on the roof of the main classroom building. Fundraising efforts included three Jog-A-Thons (raising more than $40,000) and many donations from individuals and foundations. The fundraising was completed in 1996 and a two telescope observatory was constructed in the summer of 1996 complete with warm room, CCD cameras, computers, spectrograph, video network, and computerized single channel photometer. The telescopes are computerized 16" diameter Meade LX200 Schmidt-Cassegrains, each coupled to Gateway Pentium Pro 200 MHz computers. SBIG ST-8 CCD cameras were also secured for each telescope and an Optec SSP-7 photometer and Optomechanics Research 10C Spectrograph were also purchased. A Daystar H-alpha solar filter and Thousand Oaks visual light solar filter have expanded the Observatory's functionality to daytime observing as well. This is especially useful for the thousands of school children who frequent the Planetarium each year. The Observatory primarily serves the core astronomy lab where students must observe and photograph a prescribed number of celestial objects in a semester. Advanced students can take directed studies where they conduct photometry on eclipsing binaries or other variable stars or search for new asteroids. In addition, the Observatory and Planetarium are open to the public. Interested members of the community can reserve time on the telescopes and receive training and supervision from lab assistants

  13. Social Media Programs at the National Optical Astronomy Observatory

    Science.gov (United States)

    Sparks, Robert T.; Walker, Constance Elaine; Pompea, Stephen M.

    2015-08-01

    Observatories and other science research organizations want to share their research and activities with the public. The last several years, social media has become and increasingly important venue for communicating information about observatory activities, research and education and public outreach.The National Optical Astronomy Observatory (NOAO) uses a wide variety of social media to communicate with different audiences. NOAO is active on social media platforms including Facebook, Twitter, Google+ and Pinterest. Our social media accounts include those for the National Optical Astronomy Observatory, Cerro Tololo Inter-American Observatory, Kitt Peak National Observatory and our dark skies conservation program Globe at Night.Our social media programs have a variety of audiences. NOAO uses social media to announce and promote NOAO sponsored meetings, observatory news and proposal deadlines to the professional astronomical community. Social media accounts are used to disseminate NOAO press releases, images from the observatory and other science using data from NOAO telescopes.Social media is important in our Education and Public Outreach programs (EPO). Globe at Night has very active facebook and twitter accounts encouraging people to become involved in preserving dark skies. Social media plays a role in recruiting teachers for professional development workshops such as Project Astro.NOAO produces monthly podcasts for the 365 Days of Astronomy podcast featuring interviews with NOAO astronomers. Each podcast highlights the science of an NOAO astronomer, an NOAO operated telescope or instrument, or an NOAO program. A separate series of podcasts is produced for NOAO’s Dark Skies Education programs. All the podcasts are archived at 365daysofastronomy.org.

  14. The LAGO (Large Aperture GRB Observatory) in Peru

    Science.gov (United States)

    Tueros-Cuadros, E.; Otiniano, L.; Chirinos, J.; Soncco, C.; Guevara-Day, W.

    2012-07-01

    The Large Aperture GRBs Observatory is a continental-wide observatory devised to detect high energy (around 100 GeV) component of Gamma Ray Bursts (GRBs), by using the single particle technique in arrays of Water Cherenkov Detectors (WCDs) at high mountain sites of Argentina, Bolivia, Colombia, Guatemala, Mexico, Venezuela and Peru. Details of the instalation and operation of the detectors in Marcapomacocha in Peru at 4550 m.a.s.l. are given. The detector calibration method will also be shown.

  15. miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer.

    Directory of Open Access Journals (Sweden)

    Elisabetta Crippa

    Full Text Available A miRNAs profiling on a group of familial and sporadic breast cancers showed that miRNA-342 was significantly associated with estrogen receptor (ER levels. To investigate at functional level the role of miR-342 in the pathogenesis of breast cancer, we focused our attention on its "in silico" predicted putative target gene ID4, a transcription factor of the helix-loop-helix protein family whose expression is inversely correlated with that of ER. ID4 is expressed in breast cancer and can negatively regulate BRCA1 expression. Our results showed an inverse correlation between ID4 and miR-342 as well as between ID4 and BRCA1 expression. We functionally validated the interaction between ID4 and miR-342 in a reporter Luciferase system. Based on these findings, we hypothesized that regulation of ID4 mediated by miR-342 could be involved in the pathogenesis of breast cancer by downregulating BRCA1 expression. We functionally demonstrated the interactions between miR-342, ID4 and BRCA1 in a model provided by ER-negative MDA-MB-231 breast cancer cell line that presented high levels of ID4. Overexpression of miR-342 in these cells reduced ID4 and increased BRCA1 expression, supporting a possible role of this mechanism in breast cancer. In the ER-positive MCF7 and in the BRCA1-mutant HCC1937 cell lines miR-342 over-expression only reduced ID4. In the cohort of patients we studied, a correlation between miR-342 and BRCA1 expression was found in the ER-negative cases. As ER-negative cases were mainly BRCA1-mutant, we speculate that the mechanism we demonstrated could be involved in the decreased expression of BRCA1 frequently observed in non BRCA1-mutant breast cancers and could be implicated as a causal factor in part of the familial cases grouped in the heterogeneous class of non BRCA1 or BRCA2-mutant cases (BRCAx. To validate this hypothesis, the study should be extended to a larger cohort of ER-negative cases, including those belonging to the BRCAx class.

  16. Comet Giacobini-Zinner - a normal comet?

    International Nuclear Information System (INIS)

    Cochran, A.L.; Barker, E.S.

    1987-01-01

    Observations of Comet Giacobini-Zinner were obtained during its 1985 apparition using an IDS spectrograph at McDonald Observatory. Column densities and production rates were computed. The production rates were compared to observations of other normal comets. Giacobini-Zinner is shown to be depleted in C2 and C3 relative to CN. These production rates are down by a factor of 5. 12 references

  17. Setting-up a small observatory from concept to construction

    CERN Document Server

    Arditti, David

    2008-01-01

    Every amateur astronomer who is considering a purpose-built observatory will find this book absolutely invaluable during both the planning and the construction stages. Drawing on David Arditti’s practical experience and that of many other amateur astronomers, it gives invaluable help in making all the important decisions. To begin with, Setting up a Small Observatory addresses what you really need from an observatory, whether to build or buy, what designs you should consider, and where you should site it. Uniquely, it also considers the aesthetics of an amateur observatory: how to make it fit in with your home, garden, and yard, even disguising it as a more common garden building if necessary. There’s also a wealth of practical details for constructing and equipping your small observatory – everything from satisfying local planning laws and building codes through to making sure that your completed observatory is well-equipped, convenient, and comfortable to use. Whether you are considering a simple low-...

  18. Sierra Stars Observatory Network: An Accessible Global Network

    Science.gov (United States)

    Williams, Richard; Beshore, Edward

    2011-03-01

    The Sierra Stars Observatory Network (SSON) is a unique partnership among professional observatories that provides its users with affordable high-quality calibrated image data. SSON comprises observatories in the Northern and Southern Hemisphere and is in the process of expanding to a truly global network capable of covering the entire sky 24 hours a day in the near future. The goal of SSON is to serve the needs of science-based projects and programs. Colleges, universities, institutions, and individuals use SSON for their education and research projects. The mission of SSON is to promote and expand the use of its facilities among the thousands of colleges and schools worldwide that do not have access to professional-quality automated observatory systems to use for astronomy education and research. With appropriate leadership and guidance educators can use SSON to help teach astronomy and do meaningful scientific projects. The relatively small cost of using SSON for this type of work makes it affordable and accessible for educators to start using immediately. Remote observatory services like SSON need to evolve to better support education and research initiatives of colleges, institutions and individual investigators. To meet these needs, SSON is developing a sophisticated interactive scheduling system to integrate among the nodes of the observatory network. This will enable more dynamic observations, including immediate priority interrupts, acquiring moving objects using ephemeris data, and more.

  19. Electricity and gas market observatory. 3. Quarter 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The purpose of the observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This observatory is updated every three months and data are available on CRE web site (www.cre.fr). Since the 1 of July 2007, all customers can choose their gas and electricity suppliers. The present observatory is including residential customer's statistics. Content: A - The electricity market: The retail electricity market (Introduction, Customer segments and their respective weight, Status at September 30, 2007, Dynamic analysis: 3. Quarter 2007); The wholesale electricity market (Introduction, Wholesale market activity in France, Wholesale market activity in France, Prices on the French wholesale market and European comparison, Import and export volumes, Concentration of the French electricity market); B - The gas market: The retail gas market (Introduction, Customer segments and their respective weight, Status on September 30, 2007, Dynamic analysis: 3. Quarter 2007); The wholesale gas market (Gas pricing and gas markets in Europe, The wholesale market in France); C - Appendices: Electricity and gas market observatories combined glossary, Specific electricity market observatory glossary, Specific gas market observatory glossary

  20. Efficient coding and detection of ultra-long IDs for visible light positioning systems.

    Science.gov (United States)

    Zhang, Hualong; Yang, Chuanchuan

    2018-05-14

    Visible light positioning (VLP) is a promising technique to complement Global Navigation Satellite System (GNSS) such as Global positioning system (GPS) and BeiDou Navigation Satellite System (BDS) which features the advantage of low-cost and high accuracy. The situation becomes even more crucial for indoor environments, where satellite signals are weak or even unavailable. For large-scale application of VLP, there would be a considerable number of Light emitting diode (LED) IDs, which bring forward the demand of long LED ID detection. In particular, to provision indoor localization globally, a convenient way is to program a unique ID into each LED during manufacture. This poses a big challenge for image sensors, such as the CMOS camera in everybody's hands since the long ID covers the span of multiple frames. In this paper, we investigate the detection of ultra-long ID using rolling shutter cameras. By analyzing the pattern of data loss in each frame, we proposed a novel coding technique to improve the efficiency of LED ID detection. We studied the performance of Reed-Solomon (RS) code in this system and designed a new coding method which considered the trade-off between performance and decoding complexity. Coding technique decreases the number of frames needed in data processing, significantly reduces the detection time, and improves the accuracy of detection. Numerical and experimental results show that the detected LED ID can be much longer with the coding technique. Besides, our proposed coding method is proved to achieve a performance close to that of RS code while the decoding complexity is much lower.

  1. The Inventory of Depressive Symptomatology Self Report (IDS-SR: Psychometric properties of the Indonesian version.

    Directory of Open Access Journals (Sweden)

    Retha Arjadi

    Full Text Available Depression screening and examination in Indonesia are highly challenging due to the disproportionately low number of mental health professionals in comparison to the Indonesian population. Self-report questionnaires on depression are cost-effective and time-efficient. The current study investigates the psychometric properties of the Indonesian Inventory of Depressive Symptomatology Self Report (IDS-SR.The participants were 904 Indonesians (aged 16-61; 50.2% female, recruited via an online survey using Qualtrics. Confirmatory factor analysis of the one-factor, three-factor, and four-factor model were explored. Convergent and divergent validity of the total score of the Indonesian IDS-SR and each factor were examined, as well as the Cronbach's Alpha reliability. In addition, an optimal cut-off score for the Indonesian IDS-SR was established using ROC curve analysis.The three-factor model of "cognitive/mood", "anxiety/arousal", and "sleep disturbance" was the best fit with the Indonesian IDS-SR data. Convergent and divergent validity were good. Cronbach's Alpha reliability was excellent for the total score, good for the factors "cognitive/mood" and "anxiety/arousal", but insufficient for the factor "sleep disturbance". The optimal cut-off score of the Indonesian IDS-SR was 14, with 87% sensitivity and 86% specificity.As a multifactorial instrument to measure depression that has good validity and reliability, the Indonesian IDS-SR can be used to assess depressive symptoms for the purpose of research and clinical practice. The optimal cut-off score of the Indonesian IDS-SR is in accordance with the internationally used cut-off score.

  2. Association between ACE gene I/D polymorphism and clinical presentation and prognosis of sarcoidosis.

    Science.gov (United States)

    Alía, P; Mañá, J; Capdevila, O; Alvarez, A; Navarro, M A

    2005-01-01

    Serum angiotensin converting enzyme (SACE) concentration is considered a marker of sarcoidosis activity. This concentration is influenced by an insertion/deletion (I/D) polymorphism of the ACE gene, such that SACE levels follow the pattern DD>ID>II. The aim of our work was to study the relationship between I/D polymorphism and susceptibility to sarcoidosis, as well as the relation between this polymorphism and the clinical presentation and evolution of the disease in 177 sarcoidosis patients. A group of 104 individuals without sarcoidosis was included as control. Genotyping was done by a polymerase chain reaction (PCR) method, and SACE concentration at diagnosis was determined by a kinetic method. No differences were observed in genotype or allele distributions between patients and controls, nor between patients considering the type of presentation (Löfgren versus non-Löfgren) and evolution of the disease (acute versus chronic). As reported for healthy populations, SACE concentrations followed the pattern DD>ID>II in sarcoidosis patients, but significant differences between genotypes existed only in the Löfgren group (p = 0.003) and in acute patients (p = 0.02). SACE concentrations at diagnosis were lower in acute patients (p = 0.05) and in Löfgren's syndrome (p = 0.04), but this seemed to occur only in ID individuals (p = 0.02 and p = 0.01, respectively). No relation was thus found between I/D polymorphism and susceptibility to sarcoidosis, but ACE I/D genotyping may improve the assessment of disease activity, both at diagnosis and during the follow-up of treated and untreated patients.

  3. A Global Drought Observatory for Emergency Response

    Science.gov (United States)

    Vogt, Jürgen; de Jager, Alfred; Carrão, Hugo; Magni, Diego; Mazzeschi, Marco; Barbosa, Paulo

    2016-04-01

    Droughts are occurring on all continents and across all climates. While in developed countries they cause significant economic and environmental damages, in less developed countries they may cause major humanitarian catastrophes. The magnitude of the problem and the expected increase in drought frequency, extent and severity in many, often highly vulnerable regions of the world demand a change from the current reactive, crisis-management approach towards a more pro-active, risk management approach. Such approach needs adequate and timely information from global to local scales as well as adequate drought management plans. Drought information systems are important for continuous monitoring and forecasting of the situation in order to provide timely information on developing drought events and their potential impacts. Against this background, the Joint Research Centre (JRC) is developing a Global Drought Observatory (GDO) for the European Commission's humanitarian services, providing up-to-date information on droughts world-wide and their potential impacts. Drought monitoring is achieved by a combination of meteorological and biophysical indicators, while the societal vulnerability to droughts is assessed through the targeted analysis of a series of social, economic and infrastructural indicators. The combination of the information on the occurrence and severity of a drought, on the assets at risk and on the societal vulnerability in the drought affected areas results in a likelihood of impact, which is expressed by a Likelihood of Drought Impact (LDI) indicator. The location, extent and magnitude of the LDI is then further analyzed against the number of people and land use/land cover types affected in order to provide the decision bodies with information on the potential humanitarian and economic bearings in the affected countries or regions. All information is presented through web-mapping interfaces based on OGC standards and customized reports can be drawn by the

  4. Astronomical Data Integration Beyond the Virtual Observatory

    Science.gov (United States)

    Lemson, G.; Laurino, O.

    2015-09-01

    "Data integration" generally refers to the process of combining data from different source data bases into a unified view. Much work has been devoted in this area by the International Virtual Observatory Alliance (IVOA), allowing users to discover and access databases through standard protocols. However, different archives present their data through their own schemas and users must still select, filter, and combine data for each archive individually. An important reason for this is that the creation of common data models that satisfy all sub-disciplines is fraught with difficulties. Furthermore it requires a substantial amount of work for data providers to present their data according to some standard representation. We will argue that existing standards allow us to build a data integration framework that works around these problems. The particular framework requires the implementation of the IVOA Table Access Protocol (TAP) only. It uses the newly developed VO data modelling language (VO-DML) specification, which allows one to define extensible object-oriented data models using a subset of UML concepts through a simple XML serialization language. A rich mapping language allows one to describe how instances of VO-DML data models are represented by the TAP service, bridging the possible mismatch between a local archive's schema and some agreed-upon representation of the astronomical domain. In this so called local-as-view approach to data integration, “mediators" use the mapping prescriptions to translate queries phrased in terms of the common schema to the underlying TAP service. This mapping language has a graphical representation, which we expose through a web based graphical “drag-and-drop-and-connect" interface. This service allows any user to map the holdings of any TAP service to the data model(s) of choice. The mappings are defined and stored outside of the data sources themselves, which allows the interface to be used in a kind of crowd-sourcing effort

  5. Developing the Planetary Science Virtual Observatory

    Science.gov (United States)

    Erard, Stéphane; Cecconi, Baptiste; Le Sidaner, Pierre; Henry, Florence; Chauvin, Cyril; Berthier, Jérôme; André, Nicolas; Génot, Vincent; Schmitt, Bernard; Capria, Teresa; Chanteur, Gérard

    2015-08-01

    In the frame of the Europlanet-RI program, a prototype Virtual Observatory dedicated to Planetary Science has been set up. Most of the activity was dedicated to the definition of standards to handle data in this field. The aim was to facilitate searches in big archives as well as sparse databases, to make on-line data access and visualization possible, and to allow small data providers to make their data available in an interoperable environment with minimum effort. This system makes intensive use of studies and developments led in Astronomy (IVOA), Solar Science (HELIO), and space archive services (IPDA).The current architecture connects existing data services with IVOA or IPDA protocols whenever relevant. However, a more general standard has been devised to handle the specific complexity of Planetary Science, e.g. in terms of measurement types and coordinate frames. This protocol, named EPN-TAP, is based on TAP and includes precise requirements to describe the contents of a data service (Erard et al Astron & Comp 2014). A light framework (DaCHS/GAVO) and a procedure have been identified to install small data services, and several hands-on sessions have been organized already. The data services are declared in standard IVOA registries. Support to new data services in Europe will be provided during the proposed Europlanet H2020 program, with a focus on planetary mission support (Rosetta, Cassini…).A specific client (VESPA) has been developed at VO-Paris (http://vespa.obspm.fr). It is able to use all the mandatory parameters in EPN-TAP, plus extra parameters from individual services. A resolver for target names is also available. Selected data can be sent to VO visualization tools such as TOPCAT or Aladin though the SAMP protocol.Future steps will include the development of a connection between the VO world and GIS tools, and integration of heliophysics, planetary plasma and reference spectroscopic data.The EuroPlaNet-RI project was funded by the European

  6. Quantifying Urban Groundwater in Environmental Field Observatories

    Science.gov (United States)

    Welty, C.; Miller, A. J.; Belt, K.; Smith, J. A.; Band, L. E.; Groffman, P.; Scanlon, T.; Warner, J.; Ryan, R. J.; Yeskis, D.; McGuire, M. P.

    2006-12-01

    Despite the growing footprint of urban landscapes and their impacts on hydrologic and biogeochemical cycles, comprehensive field studies of urban water budgets are few. The cumulative effects of urban infrastructure (buildings, roads, culverts, storm drains, detention ponds, leaking water supply and wastewater pipe networks) on temporal and spatial patterns of groundwater stores, fluxes, and flowpaths are poorly understood. The goal of this project is to develop expertise and analytical tools for urban groundwater systems that will inform future environmental observatory planning and that can be shared with research teams working in urban environments elsewhere. The work plan for this project draws on a robust set of information resources in Maryland provided by ongoing monitoring efforts of the Baltimore Ecosystem Study (BES), USGS, and the U.S. Forest Service working together with university scientists and engineers from multiple institutions. A key concern is to bridge the gap between small-scale intensive field studies and larger-scale and longer-term hydrologic patterns using synoptic field surveys, remote sensing, numerical modeling, data mining and visualization tools. Using the urban water budget as a unifying theme, we are working toward estimating the various elements of the budget in order to quantify the influence of urban infrastructure on groundwater. Efforts include: (1) comparison of base flow behavior from stream gauges in a nested set of watersheds at four different spatial scales from 0.8 to 171 km2, with diverse patterns of impervious cover and urban infrastructure; (2) synoptic survey of well water levels to characterize the regional water table; (3) use of airborne thermal infrared imagery to identify locations of groundwater seepage into streams across a range of urban development patterns; (4) use of seepage transects and tracer tests to quantify the spatial pattern of groundwater fluxes to the drainage network in selected subwatersheds; (5

  7. The Atsa Suborbital Observatory: An Observatory for a Commercial Suborbital Spacecraft

    Science.gov (United States)

    Vilas, F.; Sollitt, L. S.

    2012-12-01

    The advantages of astronomical observations made above Earth's atmosphere have long been understood: free access to spectral regions inaccessible from Earth (e.g., UV) or affected by the atmosphere's content (e.g., IR). Most robotic, space-based telescopes maintain large angular separation between the Sun and an observational target in order to avoid accidental damage to instruments from the Sun. For most astronomical targets, this possibility is easily avoided by waiting until objects are visible away from the Sun. For the Solar System objects inside Earth's orbit, this is never the case. Suborbital astronomical observations have over 50 years' history using NASA's sounding rockets and experimental space planes. Commercial suborbital spacecraft are largely expected to go to ~100 km altitude above Earth, providing a limited amount of time for astronomical observations. The unique scientific advantage to these observations is the ability to point close to the Sun: if a suborbital spacecraft accidentally turns too close to the Sun and fries an instrument, it is easy to land the spacecraft and repair the hardware for the next flight. Objects uniquely observed during the short observing window include inner-Earth asteroids, Mercury, Venus, and Sun-grazing comets. Both open-FOV and target-specific observations are possible. Despite many space probes to the inner Solar System, scientific questions remain. These include inner-Earth asteroid size and bulk density informing Solar System evolution studies and efforts to develop methods of mitigation against imminent impactors to Earth; chemistry and dynamics of Venus' atmosphere addressing physical phenomena such as greenhouse effect, atmospheric super-rotation and global resurfacing on Venus. With the Atsa Suborbital Observatory, we combine the strengths of both ground-based observatories and space-based observing to create a facility where a telescope is maintained and used interchangeably with both in-house facility

  8. Identification and genetic analysis of Panama-genotype Venezuelan equine encephalitis virus subtype ID in Peru.

    Science.gov (United States)

    Oberste, M S; Weaver, S C; Watts, D M; Smith, J F

    1998-01-01

    Venezuelan equine encephalitis (VEE) virus was isolated in 1993, 1994, and 1995 from human cases of acute, undifferentiated, febrile illness in the Peruvian Amazon Basin. Two virus isolates were recovered in 1994 from Peruvian soldiers at a jungle outpost near Pantoja in northern Peru, and 10 isolates were obtained from military personnel and civilians in 1993-1995 in Iquitos, an urban center in northeastern Peru. The genetic relationship of these isolates to other VEE virus strains was determined by sequencing 856-867 nucleotide reverse transcription-polymerase chain reaction fragments derived from the PE2 glycoprotein gene. The sequences were compared with those of other VEE virus strains, including representatives of the IAB, IC, ID, IE, II, and IIIC subtypes. The two Pantoja isolates were most closely related to subtype IC and ID viruses previously isolated in Colombia and Venezuela, and to the ID viruses isolated during the 1970s in Iquitos. All of the recent Iquitos isolates were similar to one another, but they were more closely related to Panamanian ID strains than to isolates previously obtained in Iquitos, Peru, or in Colombia and Venezuela. The recent Iquitos VEE viral isolates were the first Panama-genotype VEE ID virus strains identified outside of the Republic of Panama.

  9. Relationship between major depressive disorder and ACE gene I/D polymorphism in a Turkish population

    Directory of Open Access Journals (Sweden)

    Sema Inanir

    2016-04-01

    Full Text Available Abstract Background Major depressive disorder (MDD is a complex disease and a significant health problem that is prevalent across the world. Angiotensin-converting enzyme (ACE has an important role in renin-angiotensin system (RAS and converts inactive angiotensin I to a potent vasopressor and aldosterone-stimulating peptide angiotensin II. Levels of ACE in plasma vary according to the insertion/deletion (I/D polymorphism of ACE gene. Objective The aim of the current study was to examine the influence ACE gene I/D variations on the risk of MDD. Methods In the present case-control study, we analyzed ACE I/D polymorphism in 346 MDD patients and 210 healthy subjects using polymerase chain reaction technique. Results Comparing the two groups, no significant difference was observed with regard to either genotype distributions or allele frequencies of the I/D polymorphism of ACE gene. Discussion Our findings suggest that the ACE I/D polymorphism is not associated with MDD in Turkish case-control study. Further studies are still needed.

  10. An enhanced dynamic ID-based authentication scheme for telecare medical information systems

    Directory of Open Access Journals (Sweden)

    Ankita Chaturvedi

    2017-01-01

    Full Text Available The authentication schemes for telecare medical information systems (TMIS try to ensure secure and authorized access. ID-based authentication schemes address secure communication, but privacy is not properly addressed. In recent times, dynamic ID-based remote user authentication schemes for TMIS have been presented to protect user’s privacy. The dynamic ID-based authentication schemes efficiently protect the user’s privacy. Unfortunately, most of the existing dynamic ID-based authentication schemes for TMIS ignore the input verifying condition. This makes login and password change phases inefficient. Inefficiency of the password change phase may lead to denial of service attack in the case of incorrect input in the password change phase. To overcome these weaknesses, we proposed a new dynamic ID-based authentication scheme using a smart card. The proposed scheme can quickly detect incorrect inputs which makes the login and password change phase efficient. We adopt the approach with the aim to protect privacy, and efficient login and password change phases. The proposed scheme also resists off-line password guessing attack and denial of service attack. We also demonstrate the validity of the proposed scheme by utilizing the widely-accepted BAN (Burrows, Abadi, and Needham logic. In addition, our scheme is comparable in terms of the communication and computational overheads with relevant schemes for TMIS.

  11. CASK inhibits ECV304 cell growth and interacts with Id1

    International Nuclear Information System (INIS)

    Qi Jie; Su Yongyue; Sun Rongju; Zhang Fang; Luo Xiaofeng; Yang Zongcheng; Luo Xiangdong

    2005-01-01

    Calcium/calmodulin-dependent serine protein kinase (CASK) is generally known as a scaffold protein. Here we show that overexpression of CASK resulted in a reduced rate of cell growth, while inhibition of expression of endogenous CASK via RNA-mediated interference resulted in an increased rate of cell growth in ECV304 cells. To explore the molecular mechanism, we identified a novel CASK-interacting protein, inhibitor of differentiation 1 (Id1) with a yeast two-hybrid screening. Furthermore, endogenous CASK and Id1 proteins were co-precipitated from the lysates of ECV304 cells by immunoprecipitation. Mammalian two-hybrid protein-protein interaction assays indicated that CASK possessed a different binding activity for Id1 and its alternative splicing variant. It is known that Id proteins play important roles in regulation of cell proliferation and differentiation. Thus, we speculate that the regulation of cell growth mediated by CASK may be involved in Id1. Our findings indicate a novel function of CASK, the mechanism that remains to be further investigated

  12. The Einstein Observatory: A New Public/Private Observatory Complex for Community Education and Scientific Research

    Science.gov (United States)

    Sowell, J.

    1999-12-01

    The Development Authority of Cherokee County (Georgia) is leading a public/private partnership of business/industry professionals, educators, and university scientists that seeks to develop a national prototype educational and scientific research facility for grades K-12, as well as college-level research, that will inspire our youth to become literate in science and technology. In particular, the goal is to make this complex a science, math, and engineering magnet learning facility and to raise the average SAT scores of local area students by 100 points. A dark-site mountain, nestled on the foothills of the Blue Ridge Mountains at the northern-most edge of Atlanta, will become the home for the "Einstein" Observatory. The complex will have four telescopes: one 50-inch, one 24-inch, and two 16-inch telescopes. Each telescope will have digital cameras and an optic-fiber feed to a single, medium-resolution spectroscope. All four telescopes will be electronically accessible from local schools. Professional astronomers will establish suitable observational research projects and will lead K-12 and college students in the acquisition and analysis of data. Astronomers will also assist the local area schoolteachers in methods for nurturing children's scientific inquiry. The observatory mountain will have 100 platform locations for individual viewing by visiting families, school groups, and amateur astronomers. The Atlanta Astronomer Club will provide numerous evening programs and viewing opportunities for the general public. An accompanying Planetarium & Science Center will be located on the nearby campus of Reinhardt College. The Planetarium & Science Center will be integrated with Reinhardt College's theme of learning focused upon studying the past and present as a basis for projecting the future.

  13. Inhibitor of DNA binding 1 (Id1) induces differentiation and proliferation of mouse embryonic carcinoma P19CL6 cells

    International Nuclear Information System (INIS)

    Meng, Qingzhen; Jia, Zhuqing; Wang, Weiping; Li, Binhong; Ma, Kangtao; Zhou, Chunyan

    2011-01-01

    Highlights: → Id1 was upregulated during the cardiac differentiation process of P19CL6 cells. → Id1 upregulated expression of cardiac specific genes Gata4, α-MHC and ISL1. → Id1 promoted proliferation of P19CL6 cells. → Overexpression of Id1 increased activity of TOP flash. → Wnt3a or LiCl treatment promoted Id1 expression in P19CL6 cells. -- Abstract: The inhibitor of DNA binding (Id) family of genes encodes negative regulators of basic helix-loop-helix transcription factors and has been implicated in such diverse cellular processes as differentiation, proliferation, apoptosis and migration. Id knockout mouse embryos display multiple cardiac defects but the specific role of Id1 in cardiac differentiation is unclear. In the present study, we investigated the function of Id1 in DMSO-induced P19CL6 cells, a widely-accepted cell model of cardiac differentiation. We found that Id1 was upregulated during the cardiac differentiation of P19CL6 cells. The expression of cardiac specific marker genes, Gata4, α-MHC and ISL1, was upregulated in P19CL6 cells stably transfected with Id1 (P19CL6-Id1) during cardiac differentiation. The overexpression of Id1 reduced the number of cells in G1 phase and increased the cell population in G2, M and S phases, while knockdown of Id1 increased the number of cells in G1 phase from 48.6 ± 2.51% to 62.2 ± 1.52% at day 0 of cardiac induction, and from 52.5 ± 3.41% to 63.7 ± 1.02% at day 3 after cardiac induction, indicating that Id1 promoted proliferation of P19CL6 cells. Luciferase assays showed that the activity of TOP flash was higher in P19CL6-Id1 cells than wildtype P19CL6 cells, while Id1 expression was also upregulated in P19CL6 cells treated with Wnt3a or LiCl. This indicates that there may be positive feedback between Id1 and Wnt signaling which plays an important role in cardiac differentiation.

  14. Mobile Networked Sensors for Environmental Observatories

    Science.gov (United States)

    Kaiser, W. J.

    2005-12-01

    carried by NIMS include sensors for visible wavelength imaging, thermal infrared temperature mapping, microclimate, solar radiation, and for water quality and physical characterization of aquatic systems. NIMS devices include compact embedded computing, wireless network connectivity to surrounding static sensors, and remote Internet access. Exploiting this onboard computing allows NIMS devices to follow precise scanning protocols and self-calibration procedures. This presentation will describe permanent facility NIMS systems deployed at the James San Jacinto Mountains Reserve. Rapidly deployable NIMS permitting short term, highly mobile experiments will also be discussed. This includes the Thermal Mapper system that simultaneously samples plant physical structure (using laser position sensing and imaging) along with plant surface temperature (using high spatial resolution thermal infrared sensing). This compact system has been applied to the investigation of thermal characteristics of alpine plants in varying soil surfaces at the White Mountains Research Station. Other NIMS applications and results to be described include novel spatial mapping of nitrate concentration and other variables in flowing streams. Finally, this presentation will also address the many future applications of observatories linking investigators with remote mobile and static sensor networks. This research is supported by the NSF0331481 ITR program. Research has been performed in collaboration with R. Ambrose, K. Bible, D. Estrin, E. Graham, M. Hamilton, M. Hanson, T. Harmon, G. Pottie, P. Rundel, M. Srivastava, and G. Sukhatme

  15. The International Solid Earth Research Virtual Observatory

    Science.gov (United States)

    Fox, G.; Pierce, M.; Rundle, J.; Donnellan, A.; Parker, J.; Granat, R.; Lyzenga, G.; McLeod, D.; Grant, L.

    2004-12-01

    We describe the architecture and initial implementation of the International Solid Earth Research Virtual Observatory (iSERVO). This has been prototyped within the USA as SERVOGrid and expansion is planned to Australia, China, Japan and other countries. We base our design on a globally scalable distributed "cyber-infrastructure" or Grid built around a Web Services-based approach consistent with the extended Web Service Interoperability approach. The Solid Earth Science Working Group of NASA has identified several challenges for Earth Science research. In order to investigate these, we need to couple numerical simulation codes and data mining tools to observational data sets. This observational data are now available on-line in internet-accessible forms, and the quantity of this data is expected to grow explosively over the next decade. We architect iSERVO as a loosely federated Grid of Grids with each country involved supporting a national Solid Earth Research Grid. The national Grid Operations, possibly with dedicated control centers, are linked together to support iSERVO where an International Grid control center may eventually be necessary. We address the difficult multi-administrative domain security and ownership issues by exposing capabilities as services for which the risk of abuse is minimized. We support large scale simulations within a single domain using service-hosted tools (mesh generation, data repository and sensor access, GIS, visualization). Simulations typically involve sequential or parallel machines in a single domain supported by cross-continent services. We use Web Services implement Service Oriented Architecture (SOA) using WSDL for service description and SOAP for message formats. These are augmented by UDDI, WS-Security, WS-Notification/Eventing and WS-ReliableMessaging in the WS-I+ approach. Support for the latter two capabilities will be available over the next 6 months from the NaradaBrokering messaging system. We augment these

  16. Le traitement de l’idéologie dans la sociologie de Luc Boltanski

    Directory of Open Access Journals (Sweden)

    David Vrydaghs

    2006-10-01

    Full Text Available IntroductionLe concept d’idéologie apparaît dans la sociologie de Luc Boltanski à partir du Nouvel Esprit du capitalisme, publié en 1999. L’auteur y revient dans La Condition fœtale, paru en 2004. On aurait donc pu se contenter de ces ouvrages pour examiner le traitement réservé à l’idéologie dans la sociologie de Luc Boltanski. On préférera pourtant revenir aux travaux antérieurs du sociologue, et ce pour deux raisons.D’abord parce que le concept d’idéologie tel qu’il est employé dans Le Nou...

  17. Implementasi Cell ID dan GPS dalam Pencarian Lokasi Fasilitas Kesehatan Terdekat

    Directory of Open Access Journals (Sweden)

    Fahmi Candra Permana

    2017-07-01

    Full Text Available Cell ID dan GPS merupakan layanan berbasis lokasi dan teknologi yang banyak membantu manusia dalam hal navigasi dan penemuan tempat-tempat yang bermanfaat di sekitarnya. Salah satu komponen utama dari teknologi ini dapat diterapkan pada telepon seluler. Dalam penelitian ini, dirancang sebuah aplikasi dengan memanfaatkan teknologi berdasar implementasi dari Cell ID dan GPS untuk mengetahui posisi user dan lokasi fasilitas kesehatan terdekat di sekitar user dan penggunaan JSON sebagai sarana untuk menyimpan database pada web. Aplikasi ini diimplementasikan pada telepon seluler dengan sistem operasi Android. Hasil dari penelitian ini menunjukkan bahwa Cell ID dan GPS dapat diimplementasikan dengan baik dengan memanfaatkan akses Internet dan Google Maps untuk mencari fasilitas kesehatan terdekat dan menggambarkan daerah sekitar user.

  18. The Architectural and Instrumental Heritage of the Strasbourg University Observatory

    Science.gov (United States)

    Davoigneau, Jean

    When, in 1872, Alsace was handed over to Germany, Empperor Wilhelm I decided to make Strasbourg the showcase of his empire, and in particular to build a prestigious university and an observatory. The construction of the observatory was entrusted to the astronomer August Winnecke (1835-1897), former director of the Pulkovo observatory, and to the Baumeister Hermann Eggert. Begun in 1876, the work was completed in 1880. The astronomical instruments, ordered from German makers, were installed during the winter of 1880-1881, and the observatory was inaugurated on September 22, 1881 at the general assembly of the Astronomische Gesellschaft, the international association of astronomers, whose secretary was Winnecke. Marking the south-eastern extremity of the ‘imperial axis’, the architecture of the university observatory harmonizes perfectly with the new German city built on the former French parade grounds. The astronomical heritage operation conducted at the beginning of the present decade provides a richly docurnented and illustrated inventory of both the architecture and instruments of this institution. This work has also highlighted the unique quality of the collection of instruments, befitting the long and complex history of this institution.

  19. Electricity and gas market observatory. 2. quarter 2007

    International Nuclear Information System (INIS)

    2007-01-01

    Since July 1, 2004, all electricity and gas consumers can be eligible according to their consumption site, as long as all or part of the electricity or gas consumed is designed for non-residential use. The purpose of the observatory is to provide the general public with indicators for monitoring market deregulation. It both covers the wholesale and retail electricity and gas markets in Metropolitan France. This observatory is updated every three months and data are available on CRE web-site (www.cre.fr). It presents: The electricity market; The retail electricity market: Non-residential customer segments and their respective weights, Status at July 1, 2007, Dynamic analysis: 2. Quarter 2007; The wholesale electricity market: Wholesale market activity in France, Prices on the French wholesale market and European comparison, Import and export volumes, Concentration of the French electricity market, Striking facts of the second quarter 2007; The gas market; The retail gas market: The non-residential customer segments and their respective weights, Status at July 1. 2007; The wholesale gas market: Gas pricing and gas markets in Europe,The wholesale market in France. Some glossaries are attached to the document: Electricity and gas market observatories combined glossary; Specific electricity market observatory glossary; Specific gas market observatory glossary

  20. Improving geomagnetic observatory data in the South Atlantic Anomaly

    Science.gov (United States)

    Matzka, Jürgen; Morschhauser, Achim; Brando Soares, Gabriel; Pinheiro, Katia

    2016-04-01

    The Swarm mission clearly proofs the benefit of coordinated geomagnetic measurements from a well-tailored constellation in order to recover as good as possible the contributions of the various geomagnetic field sources. A similar truth applies to geomagnetic observatories. Their scientific value can be maximised by properly arranging the position of individual observatories with respect to the geometry of the external current systems in the ionosphere and magnetosphere, with respect to regions of particular interest for secular variation, and with respect to regions of anomalous electric conductivity in the ground. Here, we report on our plans and recent efforts to upgrade geomagnetic observatories and to recover unpublished data from geomagnetic observatories at low latitudes in the South Atlantic Anomaly. In particular, we target the magnetic equator with the equatorial electrojet and low latitudes to characterise the Sq- and ring current. The observatory network that we present allows also to study the longitudinal structure of these external current systems. The South Atlantic Anomaly region is very interesting due to its secular variation. We will show newly recovered data and comparisons with existing data sets. On the technical side, we introduce low-power data loggers. In addition, we use mobile phone data transfer, which is rapidly evolving in the region and allows timely data access and quality control at remote sites that previously were not connected to the internet.