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Sample records for matuyama reverse chron

  1. Evidence for a new geomagnetic reversal from lava flows in Idaho: discussion of short polarity reversals in the Brunhes and late Matuyama Polarity Chrons

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    Champion, D.E.; Lanphere, M.A.; Kuntz, M.A.

    1988-01-01

    K-Ar ages and paleomagnetic data for basalt samples from a new core hole (site E) at the Idaho National Engineering Laboratory (INEL) indicate that the age of the reversed polarity event recorded in Snake River Plain lavas is older than 465 ?? 50 ka (1000 years before present) reported previously by Champion et al. (1981). A review of data documenting short reversal records from volcanic and sedimentary rocks shows that there is evidence for eight polarity subchrons in the Brunhes and two besides the Jaramillo in the late Matuyama. These 10 short subchrons begin to indicate the many short events that Cox (1968) hypothesized must exist if polarity interval lengths have a Poisson distribution. The mean sustained polarity interval length since late Matuyama Chron time is 90 000 years. The similarity of this number with the 105-year period of the Earth's orbital eccentricity suggests anew that linkage between geomagnetic, paleoclimatic, and possible underlying Earth orbital parameters should be evaluated. -from Authors

  2. Two normal paleomagnetic polarity intervals in the lower Matuyama Chron recorded in the Shungura Formation (Omo Valley, Southwest Ethiopia)

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    Kidane, Tesfaye; Otofuji, Yo-Ichiro; Brown, Francis H.; Takemoto, Kazuhiro; Eshete, Getachew

    2007-10-01

    Two hundred fifty meters of fluvio-lacustrine deposits were sampled from the 760-meter thick Shungura Formation to study magnetostratigraphy within the lower Matuyama Chron. Two to three block samples (at different positions) were collected from 46 units in the section. Characteristic remanent magnetization (ChRM) is isolated at temperatures between 390 °C and 620 °C or alternating fields between 25 and 100 mT. The ChRM is carried by detrital magnetite and maghemite. Directional analyses revealed three reversed and three normal polarity zones: R3-N3-R2-N2-R1-N1 in the sequence. The overall mean direction Ds = 359.1°, Is = 3.4°; α95 = 3.9°, N = 44 differs marginally from the expected mean dipole field direction ( D = 1.0°, I = 8.8°, α95 = 2.3°, N = 26) [Besse, J., Courtillot, V., 2003. Apparent and True Polar wander and the geometry of the geomagnetic field in the last 200 million years. J. Geophys. Res. 108 (B10), 2469. doi 10.1029/2003JB002684]. Using stratigraphic scaling between 40Ar/ 39Ar and K/Ar isotopic age data [Brown, F.H., McDougall, I., Davies, I., Maier, R., 1985. An integrated Plio-Pleistocene chronology for the Turkana basin. In: Delson, E. (Ed.), Ancestors: The Hard Evidence. Alan R. Liss, Inc., New York, pp. 82-90; McDougall, I., Brown, F.H., 2006. Precise 40Ar/ 39Ar geochronology for the upper Koobi Fora Foramtions, Turkana Basin, northern Kenya. J. Geo. Soc. (Lond.) 163, 205-220], the normal zones N3, N2, and N1 are dated between 2.06 ± 0.01-2.08 ± 0.01 Ma, 2.15 ± 0.01-2.20 ± 0.01 Ma, and at 1.93 ± 0.02 Ma respectively. These age estimates imply that N1 represents the bottom of the Olduvai Subchron while N2 and N3 might represent Réunion Subchrons. If the sedimentation rates are assumed to be constant, the duration for the older Réunion (I) Subchron is about four to seven times (57 ± 15 kyr) that currently adopted by the recent GPTS [Cande, S.C., Kent, D.V., 1995. Revised calibration of the geomagnetic polarity timescale for the

  3. Extremely rapid directional change during Matuyama-Brunhes geomagnetic polarity reversal

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    Sagnotti, Leonardo; Scardia, Giancarlo; Giaccio, Biagio; Liddicoat, Joseph C.; Nomade, Sebastien; Renne, Paul R.; Sprain, Courtney J.

    2014-11-01

    We report a palaeomagnetic investigation of the last full geomagnetic field reversal, the Matuyama-Brunhes (M-B) transition, as preserved in a continuous sequence of exposed lacustrine sediments in the Apennines of Central Italy. The palaeomagnetic record provides the most direct evidence for the tempo of transitional field behaviour yet obtained for the M-B transition. 40Ar/39Ar dating of tephra layers bracketing the M-B transition provides high-accuracy age constraints and indicates a mean sediment accumulation rate of about 0.2 mm yr-1 during the transition. Two relative palaeointensity (RPI) minima are present in the M-B transition. During the terminus of the upper RPI minimum, a directional change of about 180 ° occurred at an extremely fast rate, estimated to be less than 2 ° per year, with no intermediate virtual geomagnetic poles (VGPs) documented during the transit from the southern to northern hemisphere. Thus, the entry into the Brunhes Normal Chron as represented by the palaeomagnetic directions and VGPs developed in a time interval comparable to the duration of an average human life, which is an order of magnitude more rapid than suggested by current models. The reported investigation therefore provides high-resolution integrated palaeomagnetic and radioisotopic data that document the fine details of the anatomy and tempo of the M-B transition in Central Italy that in turn are crucial for a better understanding of Earth's magnetic field, and for the development of more sophisticated models that are able to describe its global structure and behaviour.

  4. Cosmogenic signature of geomagnetic reversals and excursions from the Réunion event to the Matuyama-Brunhes transition (0.7-2.14 Ma interval)

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    Simon, Quentin; Bourlès, Didier L.; Thouveny, Nicolas; Horng, Chorng-Shern; Valet, Jean-Pierre; Bassinot, Franck; Choy, Sandrine

    2018-01-01

    Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Following several studies dealing with the Brunhes chron and the Matuyama-Brunhes transition, this study presents a new authigenic 10Be/9Be ratio (Be-ratio) record obtained from the MD97-2143 core (western Pacific Ocean). This new Be-ratio series yields a record of GDM variations covering the early Brunhes and mid to late Matuyama time period (i.e. 700-2140 ka), independently from the relative paleointensity (RPI) record obtained from the same core, that can be compared with available RPI records and stacks. Stratigraphic offsets measured between the Be-ratio peaks and the corresponding RPI minima reach 2 to 14 cm. They can be assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 2 to 12 ka in the studied core. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Beryllium-10 (BeDiMo) was compiled and calibrated using absolute paleointensity data. This independent record complements the available paleomagnetic RPI records, permitting 1) to overcome the pDRM lock-in offsets induced below the mixing layer, 2) to confront and increase the robustness and precision of GDM reconstructions and, 3) to better constrain the chronology of geomagnetic field instabilities during the mid to late Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to geomagnetic polarity reversals and events (Matuyama-Brunhes transition, Jaramillo and Olduvai subchron boundaries, Cobb Mountain, Réunion) and it strengthens the occurrence of several excursions (Kamikatsura, Santa

  5. 40Ar/39Ar Dating of the Brunhes-Matuyama Geomagnetic Field Reversal.

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    Baksi, A K; Hsu, V; McWilliams, M O; Farrar, E

    1992-04-17

    Magnetostratigraphic studies are widely used in conjunction with the geomagnetic polarity time scale (GPTS) to date events in the range 0 to 5 million years ago. A critical tie point on the GPTS is the potassium-argon age of the most recent (Brunhes-Matuyama) geomagnetic field reversal. Astronomical values for the forcing frequencies observed in the oxygen isotope record in Ocean Drilling Project site 677 suggest that the age of this last reversal is 780 ka (thousand years ago), whereas the potassium-argon-based estimate is 730 ka. Results from 4039; Ar incremental heating studies on a series of lavas from Maui that straddle the Brunhes-Matuyama reversal give an age of 783 + 11 ka, in agreement with the astronomically derived value. The astronomically based technique appears to be a viable tool for dating young sedimentary sequences.

  6. An integrated natural remanent magnetization acquisition model for the Matuyama-Brunhes reversal recorded by the Chinese loess

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    Jin, Chunsheng; Liu, Qingsong; Hu, Pengxiang; Jiang, Zhaoxia; Li, Cange; Han, Peng; Yang, Huihui; Liang, Wentian

    2016-08-01

    Geomagnetic polarity reversal boundaries are key isochronous chronological controls for the long Chinese loess sequences, and further facilitate paleoclimatic correlation between Chinese loess and marine sediments. However, owing to complexity of postdepositional remanent magnetization (pDRM) acquisition processes related to variable dust sedimentary environments on the Chinese Loess Plateau (CLP), there is a long-standing dispute concerning the downward shift of the pDRM recorded in Chinese loess. In this study, after careful stratigraphic correlation of representative climatic tie points and the Matuyama-Brunhes boundaries (MBB) in the Xifeng, Luochuan, and Mangshan loess sections with different pedogenic environments, the downward shift of the pDRM is semiquantitatively estimated and the acquisition model for the loess natural remanent magnetization (NRM) is discussed. The measured MB transition zone has been affected by the surficial mixing layer (SML) and remagnetization. Paleoprecipitation is suggested to be the dominant factor controlling the pDRM acquisition processes. Rainfall-controlled leaching would restrict the efficiency of the characterized remanent magnetization carriers aligning along the ancient geomagnetic field. We conclude that the MBB in the central CLP with moderate paleoprecipitation could be considered as an isochronous chronological control after moderate upward adjustment. A convincing case can then be made to correlate L8/S8 to MIS 18/19.

  7. 10Be evidence for the Matuyama-Brunhes geomagnetic reversal in the EPICA Dome C ice core.

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    Raisbeck, G M; Yiou, F; Cattani, O; Jouzel, J

    2006-11-02

    An ice core drilled at Dome C, Antarctica, is the oldest ice core so far retrieved. On the basis of ice flow modelling and a comparison between the deuterium signal in the ice with climate records from marine sediment cores, the ice at a depth of 3,190 m in the Dome C core is believed to have been deposited around 800,000 years ago, offering a rare opportunity to study climatic and environmental conditions over this time period. However, an independent determination of this age is important because the deuterium profile below a depth of 3,190 m depth does not show the expected correlation with the marine record. Here we present evidence for enhanced 10Be deposition in the ice at 3,160-3,170 m, which we interpret as a result of the low dipole field strength during the Matuyama-Brunhes geomagnetic reversal, which occurred about 780,000 years ago. If correct, this provides a crucial tie point between ice cores, marine cores and a radiometric timescale.

  8. Constraining the age of the Matuyama-Brunhes reversal using intercalibrated 40Ar/39Ar and astronomical ages of the Bishop Tuff and Australasian Tektite

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Palike, Heiko

    Recent high-resolution δ18O records from North Atlantic (I)ODP cores, with reliable paleomagnetic signals, have placed the mean age of the Matuyama-Brunhes (MB) geomagnetic polarity reversal ca. 8 ka younger than previous estimates when correlated to ice-volume age models (Channell et al., 2010...... with sedimentation rates determined through drill core analysis, we approach the MB boundary from both sides to arrive at a boundary age that is consistent with independent astronomical ages proposed for the polarity transition. This novel approach provides a best-fit age for the MB boundary that incorporates radio......-isotopic dating, astrochronologies, and sedimentation rates. The research leading to these results has received funding from the European Community's Seventh Framework Programme [FP7/2007-2013] under grant agreement no. 215458....

  9. Does Deccan Volcanic Sequence contain more reversals than the three-Chron N-R-N flow magnetostratigraphy?- A paleomagnetic evidence from the dyke-swarm near Mumbai

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    Basavaiah, N.; Satyanarayana, KVV; Deenadayalan, K.; Prasad, JN

    2018-02-01

    New paleomagnetic data from a series of Deccan-age dykes cutting across the basement of lava flows along east and south of Mumbai (18°-19° N and 72°-73.5° E) have uncovered both normal (N) and reverse (R) magnetizations. Out of 33 dykes investigated, 29 dykes have yielded stable characteristic remanent magnetizations (ChRM) amenable for statistical analysis. Twenty dykes exhibit N-polarity and nine dykes show R-polarity. The tilt-corrected dyke VGPs reveal two distinct groups of dykes. Each group consists of both N- and R- polarity dykes on the Indian Apparent Polar Wander Path (APWP). The mean of N-polarity dykes is antipodal to the mean of R-polarity dykes. Group I (GI) comprises nine N-polarity dykes with their mean at Dm = 337.8°, Im = -39.4° (k = 130.7, α95 = 4.5°), and three dykes of R-polarity whose mean is at Dm = 150.7°, Im = 44.1° (k = 147.1, α95 = 10.2°). The corresponding pole positions are at 43.5° S, 102.6° E (A95 = 4.6°) and 36.6° S, 107.6° E (A95 = 8.9°) respectively. These pole positions fall close to 65 Ma old Deccan Superpole (DSP) on the APWP, and may therefore be associated with magnetic Chron 29 N for the N-polarity and 29R for the R-polarity of the three-Chron (30N - 29R -29Ν) magnetostratigraphy of the Deccan Volcanic Province (DVP) used in the computation of DSP. In Group II (GII), eleven dykes display N-polarity with mean at Dm = 312.6°, Im = -45.2° (k = 93.3, α95 = 4.8°) and six dykes show R-polarity with mean at Dm = 130.1°, Im = 48.0° (k = 176.8, α95 = 5.1°). The corresponding pole positions at 25° S, 120.1° E (A95 = 5.3°) and 22.2° S, 119.1° E (A95 = 5.2°) respectively are significantly displaced (by more than 20°) from the DSP along the older segment (˜80 -90 Ma) of the Indian APWP. Hence, the dykes of GII appear to have been emplaced in an earlier episodic Deccan activity than that represented by the DSP. The paleolatituides corresponding to GI and GII are 23.2° S ± 4.0 and 27.6° S ± 4

  10. Matuyama/Brunhes Polarity Transition in Owens Lake, CA, Sediment

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    Liddicoat, Joseph; Kravchinsky, Vadim

    2014-05-01

    The complexity of the Matuyama/Brunhes (M/B) polarity transition is becoming better understood from investigations of volcanic rocks (Coe et al., 2004), loess (Jin et al., 2012; Evans et al., 2011; Kravchinsky, 2013), and marine (Clement and Opdyke, 1982; Hartl and Tauxe, 1996; Macri et al., 2010) and lacustrine (Valet et al., 1988; Sagnotti et al., 2013) sediments. The transition appears to include a brief interval of normal polarity prior to the entry into the Brunhes Normal Chron (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011), and the transition has Virtual Geomagnetic Poles rapidly moving from the Southern Hemisphere to the Northern Hemisphere (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011; Sagnotti et al., 2013). The M/B polarity transition is recorded in exposed Pleistocene lake sediments near Bishop, CA, where the brief interval of normal polarity noted above is present and the change from full reverse to full normal polarity occurs rapidly. The brief interval of normal polarity is recorded at two sites separated laterally by about 150 m and is in single hand samples measured at vertical spacing of 2.0-2.5 cm using six samples per measured level and alternating field demagnetization at 20 mT (Liddicoat, 1993, Table 1 and Fig. 8). The siltstone is unweathered glacial flour from the Sierra Nevada that borders the western side of Owens Valley where the sediments were deposited in Owens Lake. In the siltstone, the majority of the samples have a percentage of about 60 percent where the grain diameter is less than 63 micrometres, and in those samples there is about a five percent fraction when the diameter is two micrometres or less. The Total Inorganic Carbon in most samples is about 0.25 percent (Bergeron, 2013), and magnetite is the dominant carrier of the magnetization (Liddicoat, 1993). The palaeomagnetic directions recording the terminus of the full M/B transition, which occurs before the field intensity is completely recovered, spans no

  11. Does Deccan Volcanic Sequence contain more reversals than the three-Chron N-R-N flow magnetostratigraphy?—a palaeomagnetic evidence from the dyke-swarm near Mumbai

    Science.gov (United States)

    Basavaiah, N.; Satyanarayana, K. VV; Deenadayalan, K.; Prasad, J. N.

    2018-06-01

    New palaeomagnetic data from a series of Deccan-age dykes cutting across the basement of lava flows along east and south of Mumbai (18°-19°N and 72°-73.5°E) have uncovered both normal (N) and reverse (R) magnetizations. Out of 33 dykes investigated, 29 dykes have yielded stable characteristic remanent magnetizations (ChRM) amenable for statistical analysis. Twenty dykes exhibit N-polarity and nine dykes show R-polarity. The tilt-corrected dyke virtual geomagnetic poles reveal two distinct groups of dykes. Each group consists of both N- and R-polarity dykes on the Indian apparent polar wander path (APWP). The mean of N-polarity dykes is antipodal to the mean of R-polarity dykes. Group I (GI) comprises nine N-polarity dykes with their mean at Dm = 337.8°, Im = -39.4° (k = 130.7, α95 = 4.5°), and three dykes of R-polarity whose mean is at Dm = 150.7°, Im = 44.1° (k = 147.1, α95 = 10.2°). The corresponding pole positions are at 43.5°S, 102.6°E (A95 = 4.6°) and 36.6°S, 107.6°E (A95 = 8.9°) respectively. These pole positions fall close to 65 Ma old Deccan Superpole (DSP) on the APWP, and may therefore be associated with magnetic Chron 29N for the N-polarity and 29R for the R-polarity of the three-Chron (30N-29R-29Ν) magnetostratigraphy of the Deccan Volcanic Province (DVP) used in the computation of DSP. In Group II (GII), eleven dykes display N-polarity with mean at Dm = 312.6°, Im = -45.2° (k = 93.3, α95 = 4.8°) and six dykes show R-polarity with mean at Dm = 130.1°, Im = 48.0° (k = 176.8, α95 = 5.1°). The corresponding pole positions at 25°S, 120.1°E (A95 = 5.3°) and 22.2°S, 119.1°E (A95 = 5.2°) respectively are significantly displaced (by more than 20°) from the DSP along the older segment (˜80-90 Ma) of the Indian APWP. Hence, the dykes of GII appear to have been emplaced in an earlier episodic Deccan activity than that represented by the DSP. The palaeolatituides corresponding to GI and GII are 23.2°S ± 4.0 and 27.6°S ± 4

  12. Authigenic 10Be/9Be ratio signatures of the cosmogenic nuclide production linked to geomagnetic dipole moment variation since the Brunhes/Matuyama boundary.

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    Simon, Quentin; Thouveny, Nicolas; Bourlès, Didier L; Valet, Jean-Pierre; Bassinot, Franck; Ménabréaz, Lucie; Guillou, Valéry; Choy, Sandrine; Beaufort, Luc

    2016-11-01

    Geomagnetic dipole moment variations associated with polarity reversals and excursions are expressed by large changes of the cosmogenic nuclide beryllium-10 ( 10 Be) production rates. Authigenic 10 Be/ 9 Be ratios (proxy of atmospheric 10 Be production) from oceanic cores therefore complete the classical information derived from relative paleointensity (RPI) records. This study presents new authigenic 10 Be/ 9 Be ratio results obtained from cores MD05-2920 and MD05-2930 collected in the west equatorial Pacific Ocean. Be ratios from cores MD05-2920, MD05-2930 and MD90-0961 have been stacked and averaged. Variations of the authigenic 10 Be/ 9 Be ratio are analyzed and compared with the geomagnetic dipole low series reported from global RPI stacks. The largest 10 Be overproduction episodes are related to dipole field collapses (below a threshold of 2 × 10 22  Am 2 ) associated with the Brunhes/Matuyama reversal, the Laschamp (41 ka) excursion, and the Iceland Basin event (190 ka). Other significant 10 Be production peaks are correlated to geomagnetic excursions reported in literature. The record was then calibrated by using absolute dipole moment values drawn from the Geomagia and Pint paleointensity value databases. The 10 Be-derived geomagnetic dipole moment record, independent from sedimentary paleomagnetic data, covers the Brunhes-Matuyama transition and the whole Brunhes Chron. It provides new and complementary data on the amplitude and timing of millennial-scale geomagnetic dipole moment variations and particularly on dipole moment collapses triggering polarity instabilities.

  13. High-resolution record of the Matuyama-Brunhes transition constrains the age of Javanese Homo erectus in the Sangiran dome, Indonesia.

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    Hyodo, Masayuki; Matsu'ura, Shuji; Kamishima, Yuko; Kondo, Megumi; Takeshita, Yoshihiro; Kitaba, Ikuko; Danhara, Tohru; Aziz, Fachroel; Kurniawan, Iwan; Kumai, Hisao

    2011-12-06

    A detailed paleomagnetic study conducted in the Sangiran area, Java, has provided a reliable age constraint on hominid fossil-bearing formations. A reverse-to-normal polarity transition marks a 7-m thick section across the Upper Tuff in the Bapang Formation. The transition has three short reversal episodes and is overlain by a thick normal polarity magnetozone that was fission-track dated to the Brunhes chron. This pattern closely resembles another high-resolution Matuyama-Brunhes (MB) transition record in an Osaka Bay marine core. In the Sangiran sediments, four successive transitional polarity fields lie just below the presumed main MB boundary. Their virtual geomagnetic poles cluster in the western South Pacific, partly overlapping the transitional virtual geomagnetic poles from Hawaiian and Canary Islands' lavas, which have a mean (40)Ar/(39)Ar age of 776 ± 2 ka. Thus, the polarity transition is unambiguously the MB boundary. A revised correlation of tuff layers in the Bapang Formation reveals that the hominid last occurrence and the tektite level in the Sangiran area are nearly coincident, just below the Upper Middle Tuff, which underlies the MB transition. The stratigraphic relationship of the tektite level to the MB transition in the Sangiran area is consistent with deep-sea core data that show that the meteorite impact preceded the MB reversal by about 12 ka. The MB boundary currently defines the uppermost horizon yielding Homo erectus fossils in the Sangiran area.

  14. A detailed paleomagnetic and rock-magnetic investigation of the Matuyama-Bruhnes geomagnetic reversal recorded in tephra-paleosol sequence of Tlaxcala(Central Mexico

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    Ana Maria Soler-Arechalde

    2015-04-01

    Full Text Available Geomagnetic reversals are global phenomena, for about 50 years the paleomagnetists attempted to acquire as many detailed records as possible using the magnetic memory of sediments and lava flows. Yet, transitional field behavior remains poorly characterized largely because of sporadic aspect of volcanic eruptions. In some specific cases, paleosols such as those developed from alluvial or aeolian sediments, may also record the variations of the Geomagnetic Field across the polarity changes. Here, we report a detailed paleomagnetic and rock-magnetic investigation on some radiometrically dated chromic luvisols located in Central Mexico carrying detrital or chemical remanent magnetization. The research was developed in order i to demonstrate the primary origin of the magnetic remanence and ii to show that paleosoils are good candidates to provide a high resolution record of the behavior of geomagnetic field during reversals. The lower part of the paleosoil sequence shows a clearly defined reverse polarity magnetization followed by geomagnetically unstable transitional field and ended by normal polarity remanence. Our AMS and rock magnetic data suggest that magnetization is acquired during the initial stage of soil formation in context of active volcanic activity since magnetic fabric is essentially sedimentary and reverse and normal polarity paleodirections are almost antipodal. Titanomagnetites are identified as main magnetic carriers of rock-magnetic measurements including thermomagnetics and hysteresis cycles. We propose that the transition recorded in this study correspond to the B-M boundary, considering the K-Ar datings available at the sequence bottom and that the chromic luvisols are potentially good recorders of the paleosecular variation. The identification of the B-M boundary within the studied sequence has fundamental significance for improving the chronological scale of Tlaxcala paleosol-sedimentary sequence and its correlation with the

  15. A precursor to the Matuyama/Brunhes transition-field instability as recorded in pelagic sediments

    NARCIS (Netherlands)

    Hartla, Paul; Tauxe, Lisa

    1995-01-01

    The period some 20-25 kyr just prior to the most recent generally recognized geomagnetic field polarity transition, the Matuyama-to-Brunhes reversal, appears to be marked by significant geomagnetic variability, manifested as pronounced oscillations in intensity. We compare several previously

  16. Matuyama-age lithic tools from the Sima del Elefante site, Atapuerca (northern Spain).

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    Parés, Josep M; Pérez-González, Alfredo; Rosas, Antonio; Benito, A; Bermúdez de Castro, J M; Carbonell, E; Huguet, R

    2006-02-01

    Paleomagnetic results obtained from the sedimentary fill at the Sima del Elefante site in Atapuerca, Spain, reveal a geomagnetic reversal, interpreted as the Matuyama-Brunhes boundary (0.78 Ma). The uppermost lithostratigraphic units (E17 through E19), which contain Mode II and III archaeological assemblages, display normal polarity magnetization, whereas the six lowermost units (E9 through E16) yield negative latitudinal virtual geomagnetic pole positions. Units E9 through E13, all of which display reverse magnetic polarity, contain Mode I (Oldowan) lithic tools, testifying to the presence of humans in the early Pleistocene (0.78-1.77 Ma).

  17. Astronomical duration of polarity Chron C31r (lower Maastrichtian)

    DEFF Research Database (Denmark)

    Husson, Dorothee; Galbrun, Bruno; Thibault, Nicolas Rudolph

    2012-01-01

    The duration of polarity Chron C31r is estimated with a cyclostratigraphic approach. Two sites are investigated: ODP Site 762 (Indian Ocean) and the Contessa Highway section (Gubbio, Italy). Cyclostratigraphic analysis is performed on greyscale variations (Site 762) and magnetic susceptibility va...

  18. Cognitive Heterogeneous Reconfigurable Optical Networks (CHRON): Enabling Technologies and Techniques

    DEFF Research Database (Denmark)

    Tafur Monroy, Idelfonso; Zibar, Darko; Guerrero Gonzalez, Neil

    2011-01-01

    We present the approach of cognition applied to heterogeneous optical networks developed in the framework of the EU project CHRON: Cognitive Heterogeneous Reconfigurable Optical Network. We introduce and discuss in particular the technologies and techniques that will enable a cognitive optical...... network to observe, act, learn and optimizes its performance, taking into account its high degree of heterogeneity with respect to quality of service, transmission and switching techniques....

  19. Cognitive, Heterogeneous and Reconfigurable Optical Networks: The CHRON Project

    DEFF Research Database (Denmark)

    Caballero Jambrina, Antonio; Borkowski, Robert; de Miguel, Ignacio

    2014-01-01

    . The incorporation of cognitive techniques can help to optimize a network by employing mechanisms that can observe, act, learn and improve network performance, taking into account end-to-end goals. The EU project CHRON: Cognitive Heterogeneous Reconfigurable Optical Network proposes a strategy to efficiently control...... the network by implementing cognition. In this paper we present a survey of different techniques developed throughout the course of the project to apply cognition in future optical networks....

  20. Paleomagnetic reconstruction of the global geomagnetic field evolution during the Matuyama/Brunhes transition: Iterative Bayesian inversion and independent verification

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    Leonhardt, Roman; Fabian, Karl

    2007-01-01

    The Earth's magnetic field changed its polarity from the last reversed into today's normal state approximately 780 000 years ago. While before and after this so called Matuyama/Brunhes reversal, the Earth magnetic field was essentially an axial dipole, the details of its transitional structure are still largely unknown. Here, a Bayesian inversion method is developed to reconstruct the spherical harmonic expansion of this transitional field from paleomagnetic data. This is achieved by minimizing the total variational power at the core-mantle boundary during the transition under paleomagnetic constraints. The validity of the inversion technique is proved in two ways. First by inverting synthetic data sets from a modeled reversal. Here it is possible to reliably reconstruct the Gauss coefficients even from noisy records. Second by iteratively combining four geographically distributed high quality paleomagnetic records of the Matuyama/Brunhes reversal into a single geometric reversal scenario without assuming an a priori common age model. The obtained spatio-temporal reversal scenario successfully predicts most independent Matuyama/Brunhes transitional records. Therefore, the obtained global reconstruction based on paleomagnetic data invites to compare the inferred transitional field structure with results from numerical geodynamo models regarding the morphology of the transitional field. It is found that radial magnetic flux patches form at the equator and move polewards during the transition. Our model indicates an increase of non-dipolar energy prior to the last reversal and a non-dipolar dominance during the transition. Thus, the character and information of surface geomagnetic field records is strongly site dependent. The reconstruction also offers new answers to the question of existence of preferred longitudinal bands during the transition and to the problem of reversal duration. Different types of directional variations of the surface geomagnetic field

  1. Refinement on geometry of Matuyama-Brunhes polarity transition from paleomagnetic records

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    Oda, H.; Fabian, K.; Leonhardt, R.

    2012-04-01

    The Bayesian model of the Matuyama/Brunhes (MB) geomagnetic polarity reversal was extended from the previous model IMMAB4 (Leonhardt and Fabian, 2007), which was based on one volcanic record and three sedimentary records from the Atlantic sector. The essential improvement on the model was achieved by incorporating a new volcanic record from Tahiti (Mochizuki et al., 2011). This record is unique in that it contains important absolute paleointensity data for the Pacific region, which provide new constraints for the global geomagnetic reversal scenario. The full vector development of transitional geomagnetic field in the central part of the Pacific significantly stabilized the solution in this important region, which was completely missing in the previous model IMMAB4. The sedimentary high-quality record of ODP Site 769 by Oda et al. (2000) previously was only used to check the reliability of the model IMMAB4 by comparing the VGP paths of the model and the data. An integrated sedimentary record of ODP Site 769 was developed from Oda et al. (2000) in combination with the relative paleointensity record provided by Schneider et al. (1992) and Kent&Schneider (1995). The record will also be included into the construction of the new model. Additionally, two records from the Antarctic region (Guyodo et al., 2001; Macri et al., 2010) were found, and might prove useful for further refining the model. To fulfill the aim, we have also revised the data structure, and developed a GUI based correlation software to simplify refinement of the model and further development of the scheme. In the presentation, we will show the revised morphological development of the Earth's magnetic field during Matuyama-Brunhes polarity transition.

  2. ChronQC: a quality control monitoring system for clinical next generation sequencing.

    Science.gov (United States)

    Tawari, Nilesh R; Seow, Justine Jia Wen; Perumal, Dharuman; Ow, Jack L; Ang, Shimin; Devasia, Arun George; Ng, Pauline C

    2018-05-15

    ChronQC is a quality control (QC) tracking system for clinical implementation of next-generation sequencing (NGS). ChronQC generates time series plots for various QC metrics to allow comparison of current runs to historical runs. ChronQC has multiple features for tracking QC data including Westgard rules for clinical validity, laboratory-defined thresholds and historical observations within a specified time period. Users can record their notes and corrective actions directly onto the plots for long-term recordkeeping. ChronQC facilitates regular monitoring of clinical NGS to enable adherence to high quality clinical standards. ChronQC is freely available on GitHub (https://github.com/nilesh-tawari/ChronQC), Docker (https://hub.docker.com/r/nileshtawari/chronqc/) and the Python Package Index. ChronQC is implemented in Python and runs on all common operating systems (Windows, Linux and Mac OS X). tawari.nilesh@gmail.com or pauline.c.ng@gmail.com. Supplementary data are available at Bioinformatics online.

  3. The European FP7 CHRON Project: Towards Cognitive Heterogeneous Reconfigurable Optical Networks

    DEFF Research Database (Denmark)

    Miguel, I. de; Duran, R.J.; Abril, E.J.

    2010-01-01

    We provide an overview of the EU-funded CHRON project, which addresses the challenge of controlling and managing the next generation of heterogeneous optical networks supporting the Future Internet. Such networks will be of a highly heterogeneous nature in terms of both a wide variety of services...... is on the essential elements of the proposed cognitive network, in particular a cognitive decision system, an intelligent monitoring system, and a cognitive control system....

  4. Geomagnetic reversal rates following Palaeozoic superchrons have a fast restart mechanism.

    Science.gov (United States)

    Hounslow, Mark W

    2016-08-30

    Long intervals of single geomagnetic polarity (superchrons) reflect geodynamo processes, driven by core-mantle boundary interactions; however, it is not clear what initiates the start and end of superchrons, other than superchrons probably reflect lower heat flow across the core-mantle boundary compared with adjacent intervals. Here geomagnetic polarity timescales, with confidence intervals, are constructed before and following the reverse polarity Kiaman (Carboniferous-Permian) and Moyero (Ordovician) superchrons, providing a window into the geodynamo processes. Similar to the Cretaceous, asymmetry in reversal rates is seen in the Palaeozoic superchrons, but the higher reversal rates imply higher heatflow thresholds for entering the superchron state. Similar to the Cretaceous superchron, unusually long-duration chrons characterize the ∼10 Myr interval adjacent to the superchrons, indicating a transitional reversing state to the superchrons. This may relate to a weak pattern in the clustering of chron durations superimposed on the dominant random arrangement of chron durations.

  5. A high-resolution record of the Matuyama-Brunhes transition from the Mediterranean region: The Valle di Manche section (Calabria, Southern Italy)

    Science.gov (United States)

    Macrì, Patrizia; Capraro, Luca; Ferretti, Patrizia; Scarponi, Daniele

    2018-05-01

    High-resolution palaeomagnetic and rock magnetic investigations on the Valle di Manche section (Crotone Basin, Calabria, Southern Italy) provide a detailed record of the Matuyama-Brunhes (M-B) reversal that, to our best knowledge, is the only available record of the last geomagnetic reversal for the Mediterranean on-land marine stratigraphy. The M-B transition can be pinpointed precisely, as it develops within a 3-cm-thick interval located just above a prominent tephra layer (the "Pitagora ash") where the sedimentation rates are about 27 cm/kyr. Demagnetization analyses indicate a stable palaeomagnetic behaviour throughout the section for both normal and reversed polarity directions, with demagnetization vectors aligned toward the origin of Zijderveld diagrams after the removal of a small viscous low-coercivity remanence component. In the lower part of the studied interval, some samples acquired a spurious gyromagnetic remanent magnetization (GRM) during AF demagnetization in high fields. Rock magnetic analyses confirm that magnetite is the main magnetic carrier for all measured specimens, which also have an abundant paramagnetic fraction. Only the lower part of the record, well below the M-B boundary, is characterized by a downward-increasing presence of iron sulphides (greigite). According to our chronology, which is based on a robust, cross-validated age model, the final reverse-to-normal directional change of the M-B transition occurred at ca. 786.9 ± 5 ka (error includes uncertainty in orbital tuning) and was very rapid, of the order of 100 years or less.

  6. Paleomagnetic direction and paleointensity variations during the Matuyama-Brunhes polarity transition from a marine succession in the Chiba composite section of the Boso Peninsula, central Japan

    Science.gov (United States)

    Okada, Makoto; Suganuma, Yusuke; Haneda, Yuki; Kazaoka, Osamu

    2017-03-01

    The youngest geomagnetic polarity reversal, the Matuyama-Brunhes (M-B) boundary, provides an important plane of data for sediments, ice cores, and lavas. The geomagnetic field intensity and directional changes that occurred during the reversal also provide important information for understanding the dynamics of the Earth's outer core, which generates the magnetic field. However, the reversal process is relatively rapid in terms of the geological timescale; therefore, adequate temporal resolution of the geomagnetic field record is essential for addressing these topics. Here, we report a new high-resolution paleomagnetic record from a continuous marine succession in the Chiba composite section of the Kokumoto Formation of the Kazusa Group, Japan, that reveals detailed behaviors of the virtual geomagnetic poles (VGPs) and relative paleointensity changes during the M-B polarity transition. The resultant relative paleointensity and VGP records show a significant paleointensity minimum near the M-B boundary, which is accompanied by a clear "polarity switch." A newly obtained high-resolution oxygen isotope chronology for the Chiba composite section indicates that the M-B boundary is located in the middle of marine isotope stage (MIS) 19 and yields an age of 771.7 ka for the boundary. This age is consistent with those based on the latest astronomically tuned marine and ice core records and with the recalculated age of 770.9 ± 7.3 ka deduced from the U-Pb zircon age of the Byk-E tephra. To the best of our knowledge, our new paleomagnetic data represent one of the most detailed records on this geomagnetic field reversal that has thus far been obtained from marine sediments and will therefore be key for understanding the dynamics of the geomagnetic dynamo and for calibrating the geological timescale.[Figure not available: see fulltext.

  7. "Faz isso, faz aquilo, mas eu tô caindo...": compreendendo a Doença de Chron "Haz eso, haz aquello, mas yo estoy cayendo...": comprendiendo la enfermedad de Chron "Do this, do that, but I'm falling down...": understanding Chron's disease

    Directory of Open Access Journals (Sweden)

    Andrea Castelli

    2007-03-01

    Full Text Available Buscando compreender o significado e o impacto da doença de Chron na vida de seu portador, desenvolvemos este estudo, de natureza qualitativa, optando pela História Oral de Vida como referencial metodológico, tendo como base filosófica a corrente monista, advinda de Hipócrates, em que a prática médica tem por objeto a pessoa doente em sua totalidade, levando em conta seu temperamento e a sua história. A terapêutica deve restabelecer a harmonia da pessoa com seu ambiente e consigo mesma , trata-se de uma medicina integradora e dinâmica, que corresponde aos primórdios da medicina psicossomática. O estudo da doença de Chron, por meio da compreensão psicossomática, permitiu que analisássemos os sintomas, não como corpos estranhos a serem erradicados, mas como mensageiros de um apelo a ser compreendido. Por intermédio deles, pode ser resgatada a história de um indivíduo que, se conscientemente vivida e analisada, permite o desenvolvimento até níveis mais evoluídos de entendimento.Buscando comprender el significado y el impacto de la Enfermedad de Chron en la vida de su portador, desarrollamos este estudio, de naturaleza cualitativa, optando por la Historia Oral de Vida como referencial metodológico, y teniendo como base filosófica la corriente monista, advenida de Hipócrates, donde la práctica médica tiene por objeto a la persona enferma en su totalidad, teniendo en cuenta su temperamento y su historia. La terapéutica debe restablecer la armonía de la persona con su ambiente y consigo misma y se trata de una medicina integradora y dinámica, que corresponde a los inicios de la medicina psicosomática. El Estudio de la enfermedad de Chron, por medio de la comprensión psicosomática, permitió que analizásemos los síntomas, no como cuerpos extraños a ser erradicados, mas como mensajeros de un apelo a ser comprendido. Por intermedio de ellos, puede ser rescatada la historia de un individuo que, si conscientemente vivida

  8. Evidence for an increase in cosmogenic 10Be during a geomagnetic reversal

    International Nuclear Information System (INIS)

    Raisbeck, G.M.; Yiou, F.; Bourles, D.

    1985-01-01

    The authors report evidence in marine sediments for an increase in cosmogenic 10 Be production in the Earth's atmosphere during the Brunhes-Matuyama reversal 730,000 yr ago. In addition to confirming an increase in cosmogenic isotope production, the results provide information on the magnitude and duration of the geomagnetic intensity decrease during such an event, and the depth at which remanent magnetism is acquired in marine sediments. (author)

  9. The age of the Matuyama-Brunhes transition: New data from the Sulmona paleolake, Italy

    Science.gov (United States)

    Renne, P. R.; Nomade, S.; Sprain, C. J.; Sagnotti, L.; Scardia, G.; Giaccio, B.

    2014-12-01

    The age of the Matuyama-Brunhes geomagnetic polarity transition (MBT) is a key datum for the Pleistocene time scale. Modern estimates of this age vary over a range approaching the 21 ka period of an orbital precession cycle. Singer (2014) placed the transition at 776 ±2 ka, in agreement with the estimate of 773.1 ±0.8 ka of Channell et al. (2010) based on an orbitally-tuned marine ice volume age model for North Atlantic sediment cores. The 40Ar/39Ar data of Singer (2014) are from basaltic lavas with transitional paleomagnetic directions and/or anomalously low paleointensities, representing episodic sampling of the geomagnetic field with limited stratigraphic context. New data from Sulmona paleolake in central Italy (Sagnotti et al., 2014) reveals directional and relative paleointensity records with unsurpassed stratigraphic resolution of the MBT. Here, biogenic carbonates contain numerous sanidine-bearing tuffs derived from nearby volcanoes of the alkalic Roman volcanic province. These tuffs, dated in the LSCE and BGC labs, punctuate the stratigraphic record of the MBT, documenting a smoothly varying sediment accumulation rate of 20-25 cm/ka during the interval between 720-810 ka. A minimum age of 781.3 ±2.3 ka (nominal calibrations of Nomade et al., 2005 and Steiger and Jäger, 1977) for the MBT is provided by a tuff 1 m above the MBT. Linear interpolation between bracketing tuffs yields an age of 786.1 ±1.5 ka for the MBT, and indicate a duration Leonhardt and Fabian, 2007) over a time interval of several ka. Regardless of which calibrating parameters are used, our 40Ar/39Ar age for the MBT at Sulmona is 15 ±3 ka older than that of Singer (2014). These results underscore the need for high-precision dating applied to geomagnetic polarity transitions that are based on high-resolution magnetostratigraphy, in order to calibrate the GPTS and validate age models based on orbital tuning.

  10. Geomagnetic polarity transitions of the Gilbert and Gauss chrons recorded in marine marls from Sicily

    NARCIS (Netherlands)

    van Hoof, A.A.M.

    1993-01-01

    One of the most fascinating phenomena of geophysics is the fact that in the geological past the Earth's magnetic field has frequently reversed its polarity. These polarity transitions are accurately established during at least the past 165 Myr - from their recording in the ocean floor: the marine

  11. Geomagnetic polarity transitions of the Gilbert and Gauss chrons recorded in marine marls from Sicily

    NARCIS (Netherlands)

    Hoof, A.A.M. van

    1993-01-01

    One of the most fascinating phenomena of geophysics is the fact that in the geological past the Earth's magnetic field has frequently reversed its polarity. These polarity transitions are accurately established during at least the past 165 Myr - from their recording in the ocean floor: the

  12. Increased production of cosmogenic 10Be recorded in oceanic sediment sequences: Information on the age, duration, and amplitude of the geomagnetic dipole moment minimum over the Matuyama-Brunhes transition

    Science.gov (United States)

    Simon, Quentin; Thouveny, Nicolas; Bourlès, Didier L.; Bassinot, Franck; Savranskaia, Tatiana; Valet, Jean-Pierre; Aster Team

    2018-05-01

    New high-resolution authigenic 10Be/9Be ratio (Be-ratio) records covering the last geomagnetic reversal, i.e. the Matuyama-Brunhes transition (MBT), have been obtained and set on a time scale using benthic δ18O (Cibicides wuellerstorfi) records. The geographic distribution of the four studied sites allows global comparison between the North Atlantic, Indian and Pacific Oceans. All Be-ratio records contain a two-fold increase triggered by the geomagnetic dipole moment (GDM) collapse associated with the MBT. The stratigraphic position of the Be-ratio spike, relative to marine isotope stages, allows establishment of a robust astrochronological framework for the MBT, anchoring its age between 778 and 766 ka (average mid-peaks at 772 ka), which is consistent with all other available 10Be-proxy records from marine, ice and loess archives. The global 10Be atmospheric production doubling represents an increase of more than 300 atoms m-2 s-1 that is compatible with the increased magnitude of atmospheric 10Be production obtained by simulations between the present GDM and a null-GDM. The minimum 10Be-derived GDM average computed for the 776-771 ka interval is 1.7 ± 0.4 ×1022 Am2, in agreement with model simulations and absolute paleointensities of transitional lava flows.

  13. Chronic Obstructive Pulmonary Disease (COPD as a disease of early aging: Evidence from the EpiChron Cohort.

    Directory of Open Access Journals (Sweden)

    Miguel J Divo

    Full Text Available Aging is an important risk factor for most chronic diseases. Patients with COPD develop more comorbidities than non-COPD subjects. We hypothesized that the development of comorbidities characteristically affecting the elderly occur at an earlier age in subjects with the diagnosis of COPD.We included all subjects carrying the diagnosis of COPD (n = 27,617, and a similar number of age and sex matched individuals without the diagnosis, extracted from the 727,241 records of individuals 40 years and older included in the EpiChron Cohort (Aragon, Spain. We compared the cumulative number of comorbidities, their prevalence and the mortality risk between both groups. Using network analysis, we explored the connectivity between comorbidities and the most influential comorbidities in both groups. We divided the groups into 5 incremental age categories and compared their comorbidity networks. We then selected those comorbidities known to affect primarily the elderly and compared their prevalence across the 5 age groups. In addition, we replicated the analysis in the smokers' subgroup to correct for the confounding effect of cigarette smoking. Subjects with COPD had more comorbidities and died at a younger age compared to controls. Comparison of both cohorts across 5 incremental age groups showed that the number of comorbidities, the prevalence of diseases characteristic of aging and network's density for the COPD group aged 56-65 were similar to those of non-COPD 15 to 20 years older. The findings persisted after adjusting for smoking.Multimorbidity increases with age but in patients carrying the diagnosis of COPD, these comorbidities are seen at an earlier age.

  14. Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort.

    Science.gov (United States)

    Divo, Miguel J; Celli, Bartolome R; Poblador-Plou, Beatriz; Calderón-Larrañaga, Amaia; de-Torres, Juan Pablo; Gimeno-Feliu, Luis A; Bertó, Juan; Zulueta, Javier J; Casanova, Ciro; Pinto-Plata, Victor M; Cabrera-Lopez, Carlos; Polverino, Francesca; Carmona Píréz, Jonás; Prados-Torres, Alexandra; Marin, Jose M

    2018-01-01

    Aging is an important risk factor for most chronic diseases. Patients with COPD develop more comorbidities than non-COPD subjects. We hypothesized that the development of comorbidities characteristically affecting the elderly occur at an earlier age in subjects with the diagnosis of COPD. We included all subjects carrying the diagnosis of COPD (n = 27,617), and a similar number of age and sex matched individuals without the diagnosis, extracted from the 727,241 records of individuals 40 years and older included in the EpiChron Cohort (Aragon, Spain). We compared the cumulative number of comorbidities, their prevalence and the mortality risk between both groups. Using network analysis, we explored the connectivity between comorbidities and the most influential comorbidities in both groups. We divided the groups into 5 incremental age categories and compared their comorbidity networks. We then selected those comorbidities known to affect primarily the elderly and compared their prevalence across the 5 age groups. In addition, we replicated the analysis in the smokers' subgroup to correct for the confounding effect of cigarette smoking. Subjects with COPD had more comorbidities and died at a younger age compared to controls. Comparison of both cohorts across 5 incremental age groups showed that the number of comorbidities, the prevalence of diseases characteristic of aging and network's density for the COPD group aged 56-65 were similar to those of non-COPD 15 to 20 years older. The findings persisted after adjusting for smoking. Multimorbidity increases with age but in patients carrying the diagnosis of COPD, these comorbidities are seen at an earlier age.

  15. MIGRATION OF HOMININS WITH MEGAHERBIVORES INTO EUROPE VIA THE DANUBE-PO GATEWAY IN THE LATE MATUYAMA CLIMATE REVOLUTION

    Directory of Open Access Journals (Sweden)

    GIOVANNI MUTTONI

    2014-11-01

    Full Text Available We update critical reviews of sites bearing hominin remains and/or tools from Europe (including the Balkans and Greece and conclude that the only compelling evidence of hominin presence in these regions was after ~0.9 Ma (million-years-ago, bracketed by the end of the Jaramillo subchron (0.99 Ma and the Brunhes-Matuyama boundary (0.78 Ma and straddling the climatic late Early Pleistocene revolution (EPR at the onset of enhanced glacial/interglacial activity that reverberated worldwide. Europe may have become initially populated during the EPR when, possibly for the first time in the Pleistocene, vast and exploitable ecosystems were generated along the Danube-Po Gateway. These newly formed settings, characterized by lowlands with open grasslands and reduced woody cover during glacial/interglacial transitions, represented the closest analogues to the savanna environment to which several large mammals linked with hominins in a common food web were adapted. It was only after stable and vast grassland-savanna environments opened that large mammals (e.g. megaherbivores could expand into Europe along the Danube-Po Gateway in conjunction with the attached food web to which hominins belonged.

  16. Age of Mammuthus trogontherii from Kostolac, Serbia, and the entry of megaherbivores into Europe during the Late Matuyama climate revolution

    Science.gov (United States)

    Muttoni, Giovanni; Scardia, Giancarlo; Dimitrijević, Vesna; Kent, Dennis V.; Monesi, Edoardo; Mrdjić, Nemanja; Korać, Miomir

    2015-11-01

    At the Drmno open-pit coal mine near Kostolac in Serbia, a nearly complete skeleton of Mammuthus trogontherii (nicknamed Vika) was discovered in a fluvial deposit overlain by a loess-paleosol sequence where a second paleontological level named Nosak with remains of M. trogontherii was found. We studied the magnetostratigraphy of the Kostolac sedimentary sequence and found that the Vika layer dates to 0.8 Ma, shortly before the Brunhes-Matuyama boundary. In addition, according to our age model and previously reported optically stimulated luminescence and electron spin resonance dates, the Nosak fossils have an estimated age of 0.19 Ma and lived during the earliest part of Marine Isotope Stage 6. It appears therefore that at Kostolac, M. trogontherii is preserved both at its earliest occurrence at 0.8 Ma and close to its latest occurrence at 0.19 Ma, and may well have been present in between, albeit not yet found. We speculate that megaherbivores such as M. trogontherii entered Europe along a conjunct Danube-Po River migration conduit connecting western Asia-Levant with central-southern Europe where vast and exploitable ecosystems, particularly suited for steppe- or savanna-adapted megaherbivores from Asia and Africa, developed during the late early Pleistocene climate revolution at around 0.8 Ma.

  17. An early Brunhes (age for the Lower Paleolithic tool-bearing Kozarnika cave sediments, Bulgaria

    Science.gov (United States)

    Muttoni, Giovanni; Sirakov, Nikolas; Guadelli, Jean-Luc; Kent, Dennis V.; Scardia, Giancarlo; Monesi, Edoardo; Zerboni, Andrea; Ferrara, Enzo

    2017-12-01

    We present a new sedimentological profile and a magnetostratigraphy of the tool-bearing Kozarnika cave sediments from Bulgaria. Modal analysis of cave infilling sedimentary texture indicates that the tool-bearing layers contain a sizable fraction of sediment interpreted as loess. We also find evidence for a relatively thick and well defined normal magnetic polarity in the upper-middle part of the section interpreted as a record of the Brunhes Chron, followed down-section by reverse polarity directions interpreted as a record of the Matuyama Chron. The lowermost levels with Lower Paleolithic tools (Layers 13a-c) lie in the early Brunhes at a nominal maximum age of ∼0.75 Ma, while the Brunhes-Matuyama boundary (0.78 Ma) falls in Layer 13 Lower immediately below. This finding represents a conspicuous revision of previous age estimates for the same tool-bearing layers.

  18. New 40Ar/39Ar age of the Bishop Tuff from multiple sites and sediment rate calibration for the Matuyama-Brunhes boundary

    Science.gov (United States)

    Sarna-Wojcicki, A. M.; Pringle, M.S.; Wijbrans, J.

    2000-01-01

    Precise dating of sanidine from proximal ash flow Bishop Tuff and air fall Bishop pumice and ash, California, can be used to derive an absolute age of the Matuyama Reversed-Brunhes Normal (M-B) paleomagnetic transition, identified stratigraphically close beneath the Bishop Tuff and ash at many sites in the western United States. An average age of 758.9 ?? 1.8 ka, standard error of the mean (SEM), was obtained for individual sanidine crystals or groups of several crystals, determined from ???70 individual analyses of sanidine separates from 11 sample groups obtained at five localities. The basal air fall pumice (757.7 ?? 1.8 ka) and overlying ash flow tuff (762.2 ?? 4.7 ka) from near the source yield essentially the same dates within errors of analysis, suggesting that the two units were emplaced close in time. A date on distal Bishop air fall ash bed at Friant, California, ???100 km to the west of the source area, is younger, 750.1 ?? 4.3 ka, but not significantly different within analytical error (??1 standard deviation). Previous dates of the Bishop Tuff, obtained by others using conventional K-Ar and the fission track method on zircons, ranged from ???650 ka to ???1.0 Ma. The most recent, generally accepted date by the K-Ar method on sanidine was 738 ?? 3 ka. We infer, as others before, that many K-Ar dates on sanidine feldspar are too young owing to incomplete degassing of radiogenic Ar during fusion in the K-Ar technique and that many older K-Ar dates are too old owing to detrital or xenocrystic contamination in the larger samples that are necessary for the technique. The new dates are similar to recent 40Ar/39Ar ages of the Bishop Tuff determined on individual samples by others but are derived from a larger proximal sample population and from multiple analysis of each sample. The results provide a definitive and precise age calibration of this widespread chronostratigraphic marker in the western United States and northeastern Pacific Ocean. We calculated the

  19. Midlatitude cooling caused by geomagnetic field minimum during polarity reversal.

    Science.gov (United States)

    Kitaba, Ikuko; Hyodo, Masayuki; Katoh, Shigehiro; Dettman, David L; Sato, Hiroshi

    2013-01-22

    The climatic effects of cloud formation induced by galactic cosmic rays (CRs) has recently become a topic of much discussion. The CR-cloud connection suggests that variations in geomagnetic field intensity could change climate through modulation of CR flux. This hypothesis, however, is not well-tested using robust geological evidence. Here we present paleoclimate and paleoenvironment records of five interglacial periods that include two geomagnetic polarity reversals. Marine oxygen isotope stages 19 and 31 contain both anomalous cooling intervals during the sea-level highstands and the Matuyama-Brunhes and Lower Jaramillo reversals, respectively. This contrasts strongly with the typical interglacial climate that has the temperature maximum at the sea-level peak. The cooling occurred when the field intensity dropped to 40% increase in CR flux. The climate warmed rapidly when field intensity recovered. We suggest that geomagnetic field intensity can influence global climate through the modulation of CR flux.

  20. The Top Chron C27n Event in the Western Atlantic: Evidence for a transient perturbation of the carbon cycle in the Late Danian?

    Science.gov (United States)

    Schulte, Peter; Bornemann, André; Speijer, Robert P.

    2010-05-01

    The Paleocene to early Eocene is punctuated by several transient, ˜20-200 ky lasting hyperthermal events of which the Paleocene-Eocene Thermal Maximum (PETM) was the most prominent one. Abrupt shallowing of the lysocline/CCD, negative carbon isotope excursions, and benthic faunal turnover all imply a major perturbation of the ocean system during these events. Our recent research at the Southern Tethyan shelf suggests the presence of an additional hyperthermal event associated with sea-level fluctuations, the Latest Danian Event (LDE; Speijer, 2003; Bornemann et al., 2009). At Zumaia, Northern Spain, a negative ~0.5 per mil carbon isotope excursion is present in the uppermost Danian that may correlate to the LDE (Arenillas et al. 2008). Moreover, cyclostratigraphic studies have shown that several deep-sea sites are characterized by a prominent peak in both Fe and MS data at cycle Pc100-38 in the uppermost Danian: this applies to all Walvis Ridge (Atlantic) and Shatsky Rise (Pacific) sites as well as Site 1001 in the Caribbean Sea (Top Chron C27n Event; Westerhold et al., 2007). These results suggest that the LDE in the Tethys and the Top Chron C27n Event in the Atlantic may be correlative. We have conducted mineralogical, geochemical, and micropaleontological investigations to characterize this event in the Western Atlantic. Our first results from ODP Leg 165 Site 1001 show that the Top Chron 27n Event shown by Westerhold el al. (2008) corresponds to a ~12 cm thick clay layer. Mineralogical analyses reveal a sharp ~50% drop of the carbonate content in the clay layer and a disproportionally high increase of the phyllosilicate content in the insoluble residue compared to the quartz and illite content. Bulk rock isotope analyses show an abrupt negative ~0.6 per mil carbon isotope excursion at the onset of the clay layer, followed by a 1-m thick interval where carbon isotopes shows a tailing back to pre-event values. The magnitude and pattern of the carbon isotope

  1. On the age of the hominid fossils at the Sima de los Huesos, Sierra de Atapuerca, Spain: paleomagnetic evidence.

    Science.gov (United States)

    Parés, J M; Pérez-González, A; Weil, A B; Arsuaga, J L

    2000-04-01

    We report new paleomagnetic data for the Middle Pleistocene hominid-bearing strata in the Sima de los Huesos, North Spain. Sediments (brown muds with human and bear fossils and the underlying sterile clayey and sandy unit) preserve both normal and reversed magnetic components. The sterile unit has exclusively reversed magnetization, dating back to the Matuyama Chron, and thus is Lower Pleistocene in age. The overlying fossiliferous muds have a dominant normal magnetization that overprints a partially resolved reversed magnetization. These data are compatible with one of the reversal events that occurred during the Brunhes Chron. Combined with the existing U-series dates and evidence from the macro- and microfauna, these paleomagnetic results suggest an age of the hominid fossils between 325 to 205 ka, whereas the underlying sand and silts are older than 780 ka. Copyright 2000 Wiley-Liss, Inc.

  2. Structural and temporal requirements for geomagnetic field reversal deduced from lava flows.

    Science.gov (United States)

    Singer, Brad S; Hoffman, Kenneth A; Coe, Robert S; Brown, Laurie L; Jicha, Brian R; Pringle, Malcolm S; Chauvin, Annick

    2005-03-31

    Reversals of the Earth's magnetic field reflect changes in the geodynamo--flow within the outer core--that generates the field. Constraining core processes or mantle properties that induce or modulate reversals requires knowing the timing and morphology of field changes that precede and accompany these reversals. But the short duration of transitional field states and fragmentary nature of even the best palaeomagnetic records make it difficult to provide a timeline for the reversal process. 40Ar/39Ar dating of lavas on Tahiti, long thought to record the primary part of the most recent 'Matuyama-Brunhes' reversal, gives an age of 795 +/- 7 kyr, indistinguishable from that of lavas in Chile and La Palma that record a transition in the Earth's magnetic field, but older than the accepted age for the reversal. Only the 'transitional' lavas on Maui and one from La Palma (dated at 776 +/- 2 kyr), agree with the astronomical age for the reversal. Here we propose that the older lavas record the onset of a geodynamo process, which only on occasion would result in polarity change. This initial instability, associated with the first of two decreases in field intensity, began approximately 18 kyr before the actual polarity switch. These data support the claim that complete reversals require a significant period for magnetic flux to escape from the solid inner core and sufficiently weaken its stabilizing effect.

  3. Reverse Algols

    Science.gov (United States)

    Leung, K. C.

    1989-01-01

    Reverse Algols, binary systems with a semidetached configuration in which the more massive component is in contact with the critical equipotential surface, are examined. Observational evidence for reverse Algols is presented and the parameters of seven reverse Algols are listed. The evolution of Algols and reverse Algols is discussed. It is suggested that, because reverse Algols represent the premass-reversal semidetached phase of close binary evolution, the evolutionary time scale between regular and reverse Algols is the ratio of the number of confirmed systems of these two Algol types.

  4. Reverse Logistics

    OpenAIRE

    Kulikova, Olga

    2016-01-01

    This thesis was focused on the analysis of the concept of reverse logistics and actual reverse processes which are implemented in mining industry and finding solutions for the optimization of reverse logistics in this sphere. The objective of this paper was the assessment of the development of reverse logistics in mining industry on the example of potash production. The theoretical part was based on reverse logistics and mining waste related literature and provided foundations for further...

  5. Late Cenozoic Arctic Ocean sea ice and terrestrial paleoclimate.

    Science.gov (United States)

    Carter, L.D.; Brigham-Grette, J.; Marincovich, L.; Pease, V.L.; Hillhouse, J.W.

    1986-01-01

    Sea otter remains found in deposits of two marine transgressions (Bigbendian and Fishcreekian) of the Alaskan Arctic Coastal Plain which occurred between 2.4 and 3 Ma suggest that during these two events the southern limit of seasonal sea ice was at least 1600 km farther north than at present in Alaskan waters. Perennial sea ice must have been severely restricted or absent, and winters were warmer than at present during these two sea-level highstands. Paleomagnetic, faunal, and palynological data indicate that the later transgression (Fishcreekian) occurred during the early part of the Matuyama Reversed-Polarity Chron. -from Authors

  6. Reverse Osmosis

    Indian Academy of Sciences (India)

    many applications, one of which is desalination of seawater. The inaugural Nobel Prize in Chemistry was awarded in 1901 to van 't Hoff for his seminal work in this area. The present article explains the principle of osmosis and reverse osmosis. Osmosis and Reverse Osmosis. As the name suggests, reverse osmosis is the ...

  7. The quest for chron E23r at Partridge Island, bay of Fundy, Canada: CAMP emplacement postdates the end-Triassic extinction event at the North American craton

    NARCIS (Netherlands)

    Deenen, M.H.L.; Krijgsman, W.; Ruhl, M.

    2011-01-01

    The Partridge Island stratigraphic section at the Bay of Fundy, Maritime Canada, reveals a continental sedimentary succession with the end-Triassic mass extinction level closely followed by basalts of the Central Atlantic Magmatic Province (CAMP). New Paleomagnetic data show that a short reverse

  8. Magnetostratigraphy of the Koobi Fora Formation, Lake Turkana, Kenya

    Science.gov (United States)

    Hillhouse, J. W.; Cerling, T. E.; Brown, F. H.

    1986-10-01

    The Koobi Fora Formation, a Pliocene and Pleistocene sequence of sedimentary deposits northeast of Lake Turkana, has yielded numerous fossils and stone artifacts of early hominids. Stratigraphic correlation of the hominid-bearing deposits throughout the Turkana region was established primarily by the chemistry and isotopic ages of volcanic tuffs and complemented by magnetostratigraphic studies. We have reinterpreted previously published magnetostratigraphy from the upper part of the Koobi Fora Formation because the original stratigraphy and dating of tuffs have been revised. In our reinterpretation we include previously unpublished data from the uppermost part of the formation. The upper magnetozones correlate with parts of the Brunhes Normal-Polarity Chron and Matuyama Reversed-Polarity Chron (about 0.6-0.85 Ma) and are separated from the magnetozones of the upper part of the Matuyama (2.0-1.25 Ma) by a disconformity. The Olduvai Normal-Polarity Subchron is represented within the Matuyama, but the lower part of the Matuyama (2.4-2.0 Ma) is missing due to an erosional disconformity. We have also determined magnetozones in the lower part of the Koobi Fora Formation, which had not been sampled for paleomagnetism during the earlier studies. Our time calibration of the magnetozones is made possible by isotopic dating of several tuffs and by chemical correlation of Koobi Fora tuffs with dated tuffs in the Shungura Formation of southern Ethiopia. The tephra correlations are corroborated by the excellent concordance between the magnetostratigraphies of the Koobi Fora and Shungura formations. The lower part of the Koobi Fora spans the interval from about 4 Ma to 2.4 Ma, within the Gilbert Reversed-Polarity and Gauss Normal-Polarity chrons. Rock magnetic studies indicate that detrital magnetite carries most of the stable remanence, although hematite contributes to the remanence as indicated by thermal demagnetization. The hematite, which presumably formed by

  9. Reversible Statistics

    DEFF Research Database (Denmark)

    Tryggestad, Kjell

    2004-01-01

    The study aims is to describe how the inclusion and exclusion of materials and calculative devices construct the boundaries and distinctions between statistical facts and artifacts in economics. My methodological approach is inspired by John Graunt's (1667) Political arithmetic and more recent work...... within constructivism and the field of Science and Technology Studies (STS). The result of this approach is here termed reversible statistics, reconstructing the findings of a statistical study within economics in three different ways. It is argued that all three accounts are quite normal, albeit...... in different ways. The presence and absence of diverse materials, both natural and political, is what distinguishes them from each other. Arguments are presented for a more symmetric relation between the scientific statistical text and the reader. I will argue that a more symmetric relation can be achieved...

  10. Cosmogenic 10Be signature of geomagnetic dipole moment variations over the last 2 Ma

    Science.gov (United States)

    Simon, Q.; Thouveny, N.; Bourlès, D. L.; Valet, J. P.; Bassinot, F. C.; Savranskaia, T.; Duvivier, A.; Choy, S.; Gacem, L.; Villedieu, A.

    2017-12-01

    Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Authigenic 10Be/9Be ratios (Be-ratio, proxy of atmospheric 10Be production) from marine sedimentary cores give independent and additional insights on the evolution of the geomagnetic intensity, completing information from absolute and relative paleointensity (RPI) records. Here we present new Be-ratio results obtained on several marine cores from the North Atlantic, Indian and Pacific Oceans which permit to extent into the Matuyama chron our previous 10Be-derived GDM reconstructions (Simon et al., 2016 JGR 121). Stratigraphic offsets measured between Be-ratio peaks and the corresponding RPI minima in each studied cores are assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 0 to 16 cm (up to 12 ka). All these results were compiled in order to obtain a continuous Be-ratio record covering the last 2 Ma. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Be-ratio stack (BeDiMo2Ma) was calibrated using absolute paleointensity data. This independent record completes the available paleomagnetic RPI records and permits: 1) to confront and increase the robustness and precision of GDM reconstructions; and, 2) to better constrain geomagnetic field instabilities during the mid- to late- Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to polarity reversals (Matuyama-Brunhes transition, Jaramillo and Olduvai boundaries), geomagnetic events (Cobb Mountain, Réunion) and Brunhes' excursions (e.g. Laschamp, Blake, Iceland-Basin, Big Lost). It further

  11. Cognitive Optical Network Testbed: EU Project CHRON

    DEFF Research Database (Denmark)

    Borkowski, Robert; Duran, Ramon J.; Kachris, Christoforos

    2015-01-01

    The aim of cognition in optical networks is to introduce intelligence into the control plane that allows for autonomous end-to-end performance optimization and minimization of required human intervention, particularly targeted at heterogeneous network scenarios. A cognitive network observes, lear...

  12. Internal time marker (Q1) of the Cretaceous super chron in the Bay of Bengal - a new age constraint for the oceanic crust evolved between India and Elan Bank

    Science.gov (United States)

    Krishna, K. S.; Ismaiel, M.; Karlapati, S.; Saha, D.; Mishra, J.

    2014-12-01

    Analysis of marine magnetic data of the Bay of Bengal (BOB) led to suggest two different tectonic models for the evolution of lithosphere between India and East Antarctica. The first model explains the presence of M-series (M11 to M0) magnetic anomalies in BOB with a small room leaving for accommodating the crust evolved during the long Cretaceous Magnetic Quiet Period. Second model explains in other way that most part of the crust in BOB was evolved during the quite period together with the possible presence of oldest magnetic chron M1/ M0 in close vicinity of ECMI. It is with this perspective we have reinvestigated the existing and recently acquired magnetic data together with regional magnetic model of BOB for identification of new tectonic constraints, thereby to better understand the evolution of lithosphere. Analysis of magnetic data revealed the presence of spreading anomalies C33 and C34 in the vicinity of 8°N, and internal time marker (Q1) corresponding to the age 92 Ma at 12°N in a corridor between 85°E and Ninetyeast ridges. The new time marker and its location, indeed, become a point of reference and benchmark in BOB for estimating the age of oceanic crust towards ECMI. The magnetic model further reveals the presence of network of fracture zones (FZs) with different orientations. Between 85°E and Ninetyeast ridges, two near N-S FZs, approximately followed 87°E and 89.5°E are found to extend into BOB up to 12°N, from there the FZs reorient in N60°W direction and reach to the continental margin region. Along ECMI two sets of FZs are identified with a northern set oriented in N60°W and southern one in N40°W direction. This suggests that both north and south segments of the ECMI were evolved in two different tectonic settings. The bend in FZs marks the timing (92 Ma) of occurrence of first major plate reorganisation of the Indian Ocean and becomes a very critical constraint for understanding the plate tectonic process in early opening of the

  13. Geophysical evidence for widespread reversely magnetised pyroclastics in the western Taupo Volcanic Zone (New Zealand)

    International Nuclear Information System (INIS)

    Soengkono, S.; Hochstein, M.P.; Smith, I.E.M.; Itaya, T.

    1992-01-01

    Low-altitude aeromagnetic data show that negative residual anomalies are widespread over the western Taupo Volcanic Zone, New Zealand. Paleomagnetic study of eight rhyolitic ignimbrite units and two lava flows which are exposed in this area, together with new K-Ar dates of four of the ignimbrite units, indicate that the two lava units and seven of the ignimbrite units were erupted during the Matuyama geomagnetic epoch (>0.73 Ma B.P.) and suggest that rhyolitic volcanism in the western Taupo Volcanic Zone began as early as 1.6 Ma B.P. These results provide the basis for an interpretation of our aeromagnetic data which confirms the hypothesis that the magnetic anomalies observed in the western Taupo Volcanic Zone are caused by widespread, thick, reversely magnetised pyroclastic and lava flows. Magnetic modelling also allows thickness estimates of the younger, normally magnetised cover rocks which reach a maximum thickness of the order of 0.5 km in the Mangakino area. The magnetic structure of these volcanic rocks defines approximately the lateral extent of the Mangakino Volcanic Centre. (author). 41 refs., 2 figs., 3 tabs

  14. MAGNETOSTRATIGRAPHY OF THE HOMO-BEARING PLEISTOCENE DANDIERO BASIN (DANAKIL DEPRESSION, ERITREA

    Directory of Open Access Journals (Sweden)

    ANDREA ALBIANELLI

    2004-12-01

    Full Text Available Four magnetozones have been found in the 530 m thick profile of the Dandiero Group. The lower unit, the Bukra Sand and Gravel, extends in the R1 reversed magnetozone from 150 m below the tephra level which was used as the reference marker between the sampled sections. The normal magnetozone N1 is almost completely covered by the lacustrine and deltaic sediments of the Alat Formation, while the following reversed magnetozone contains both the Wara Sand and Gravel and the lacustrine Goreya Fm. The N2 polarity zone is completely occupied by the Aro Sand. This polarity sequence has been calibrated to the geomagnetic time scale using the Early to Middle Pleistocene age of the associated vertebrate fauna and fission-track dating. The four magnetozones were thus regarded as representing the chrons by which the Pleistocene is correlated with magnetochronology. Their three reversal boundaries provided the dates of 1.07, 0.99 and 0.78 Ma, allowing to determine average sedimentation rates close to 1 m/ky. Cyclostratigraphy of the magnetic signal, analysed by the spectral analysis of the time series across the Jaramillo and late Matuyama chrons, confirmed that value. The evidenced cyclicities were directly related to the alternating lithofacies, and both to the astronomical parameters driving the climate changes during the deposition of the Dandiero group (some five hundred thousand years. The section with the Homo site covers the Jaramillo/Matuyama boundary, and the Homo bed located 2 m below this limit is dated 0.992 Ma. 

  15. A Quaternary Geomagnetic Instability Time Scale

    Science.gov (United States)

    Singer, B. S.

    2013-12-01

    Reversals and excursions of Earth's geomagnetic field create marker horizons that are readily detected in sedimentary and volcanic rocks worldwide. An accurate and precise chronology of these geomagnetic field instabilities is fundamental to understanding several aspects of Quaternary climate, dynamo processes, and surface processes. For example, stratigraphic correlation between marine sediment and polar ice records of climate change across the cryospheres benefits from a highly resolved record of reversals and excursions. The temporal patterns of dynamo behavior may reflect physical interactions between the molten outer core and the solid inner core or lowermost mantle. These interactions may control reversal frequency and shape the weak magnetic fields that arise during successive dynamo instabilities. Moreover, weakening of the axial dipole during reversals and excursions enhances the production of cosmogenic isotopes that are used in sediment and ice core stratigraphy and surface exposure dating. The Geomagnetic Instability Time Scale (GITS) is based on the direct dating of transitional polarity states recorded by lava flows using the 40Ar/39Ar method, in parallel with astrochronologic age models of marine sediments in which O isotope and magnetic records have been obtained. A review of data from Quaternary lava flows and sediments yields a GITS comprising 10 polarity reversals and 27 excursions during the past 2.6 million years. Nine of the ten reversals bounding chrons and subchrons are associated with 40Ar/39Ar ages of transitionally-magnetized lava flows. The tenth, the Guass-Matuyama chron boundary, is tightly bracketed by 40Ar/39Ar dated ash deposits. Of the 27 well-documented excursions, 14 occurred during the Matuyama chron and 13 during the Brunhes chron; 19 have been dated directly using the 40Ar/39Ar method on transitionally-magnetized volcanic rocks and form the backbone of the GITS. Excursions are clearly not the rare phenomena once thought

  16. Managing Reverse Logistics or Reversing Logistics Management?

    OpenAIRE

    Brito, Marisa

    2004-01-01

    textabstractIn the past, supply chains were busy fine-tuning the logistics from raw material to the end customer. Today an increasing flow of products is going back in the chain. Thus, companies have to manage reverse logistics as well.This thesis contributes to a better understanding of reverse logistics. The thesis brings insights on reverse logistics decision-making and it lays down theoretical principles for reverse logistics as a research field.In particular it puts together a framework ...

  17. High-resolution rock-magnetic variability in shallow marine sediment: a sensitive paleoclimatic metronome

    Science.gov (United States)

    Arai, Kohsaku; Sakai, Hideo; Konishi, Kenji

    1997-05-01

    An outer shelf deposit in central Japan centered on the Olduvai normal polarity event in the reversed Matuyama chron reveals a close correlation of both the magnetic susceptibility and remanent intensity with the sedimentary cyclicities apparent in lithologies and molluscan assemblages. Two sedimentary cycles are characterized by distinctly similar, but double-peaked magnetic cyclicities. The rock-magnetic variability is primarily attributed to the relative abundance of terrigenous magnetic minerals, and the double peak of the variability is characterized by the concentration of finer-grained magnetic minerals. The concentration is suspected to be controlled by both climatic change and shifting proximity of the shoreline as a function of rise and fall of the sea level due to glacio-eustasy. Rock-magnetic study reveals the record of a 21 ka period of orbital precession cycles within the sedimentary cyclicity attributable to a 41 ka period of orbital obliquity forcing.

  18. Managing Reverse Logistics or Reversing Logistics Management?

    NARCIS (Netherlands)

    M.P. de Brito (Marisa)

    2004-01-01

    textabstractIn the past, supply chains were busy fine-tuning the logistics from raw material to the end customer. Today an increasing flow of products is going back in the chain. Thus, companies have to manage reverse logistics as well.This thesis contributes to a better understanding of reverse

  19. Reversible Thermoset Adhesives

    Science.gov (United States)

    Mac Murray, Benjamin C. (Inventor); Tong, Tat H. (Inventor); Hreha, Richard D. (Inventor)

    2016-01-01

    Embodiments of a reversible thermoset adhesive formed by incorporating thermally-reversible cross-linking units and a method for making the reversible thermoset adhesive are provided. One approach to formulating reversible thermoset adhesives includes incorporating dienes, such as furans, and dienophiles, such as maleimides, into a polymer network as reversible covalent cross-links using Diels Alder cross-link formation between the diene and dienophile. The chemical components may be selected based on their compatibility with adhesive chemistry as well as their ability to undergo controlled, reversible cross-linking chemistry.

  20. Tubal Ligation Reversal

    Science.gov (United States)

    ... seal off the fallopian tubes, such as the Essure or Adiana systems, generally aren't reversible. Why ... electrocautery). Some types of sterilization, such as the Essure or Adiana systems, aren't considered reversible. Risks ...

  1. Reverse logistics - a framework

    NARCIS (Netherlands)

    M.P. de Brito (Marisa); R. Dekker (Rommert)

    2002-01-01

    textabstractIn this paper we define and compare Reverse Logistics definitions. We start by giving an understanding framework of Reverse Logistics: the why-what-how. By this means, we put in context the driving forces for Reverse Logistics, a typology of return reasons, a classification of

  2. Reversible flowchart languages and the structured reversible program theorem

    DEFF Research Database (Denmark)

    Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert

    2008-01-01

    Many irreversible computation models have reversible counterparts, but these are poorly understood at present. We introduce reversible flowcharts with an assertion operator and show that any reversible flowchart can be simulated by a structured reversible flowchart using only three control flow...... operators. Reversible flowcharts are r- Turing-complete, meaning that they can simuluate reversible Turing machines without garbage data. We also demonstrate the injectivization of classical flowcharts into reversible flowcharts. The reversible flowchart computation model provides a theoretical...

  3. The NE Rift of Tenerife: towards a model on the origin and evolution of ocean island rifts; La dorsal NE de Tenerife: hacia un modelo del origen y evolucion de los rifts de islas oceanicas

    Energy Technology Data Exchange (ETDEWEB)

    Carracedo, J. C.; Guillou, H.; Rodriguez Badiola, E.; Perez-Torrado, F. J.; Rodriguez Gonzalez, A.; Peris, R.; Troll, V.; Wiesmaier, S.; Delcamp, A.; Fernandez-Turiel, J. L.

    2009-07-01

    The NE Rift of Tenerife is an excellent example of a persistent, recurrent rift, providing important evidence of the origin and dynamics of these major volcanic features. The rift developed in three successive, intense and relatively short eruptive stages (a few hundred ka), separated by longer periods of quiescence or reduced activity: A Miocene stage (7266 {+-}156 ka), apparently extending the central Miocene shield of Tenerife towards the Anaga massif; an Upper Pliocene stage (2710{+-} 58 ka) and the latest stage, with the main eruptive phase in the Pleistocene. Detailed geological (GIS) mapping, geomagnetic reversal mapping and stratigraphic correlation, and radioisotopic (K/Ar) dating of volcanic formations allowed the reconstruction of the latest period of rift activity. In the early phases of this stage the majority of the eruptions grouped tightly along the axis of the rift and show reverse polarity (corresponding to the Matuyama chron). Dykes are of normal and reverse polarities. In the final phase of activity, eruptions are more disperse and lavas and dykes are consistently of normal polarity (Brunhes chron). Volcanic units of normal polarity crossed by dykes of normal and reverse polarities yield ages apparently compatible with normal subchrons (M-B Precursor and Jaramillo) in the Upper Matuyama chron. Three lateral collapses successively mass-wasted the rift: The Micheque collapse, completely concealed by subsequent nested volcanism, and the Guimar and La Orotava collapses, that are only partially filled. Time occurrence of collapses in the NE rift apparently coincides with glacial stages, suggesting that giant landslides may be finally triggered by sea level chan-ges during glaciations. Pre-collapse and nested volcanism is predominantly basaltic, except in the Micheque collapse, where magmas evolved towards intermediate and felsic (trachytic) compositions. Rifts in the Canary Islands are long-lasting, recurrent features, probably related to primordial

  4. Introduction to reversible computing

    CERN Document Server

    Perumalla, Kalyan S

    2013-01-01

    Few books comprehensively cover the software and programming aspects of reversible computing. Filling this gap, Introduction to Reversible Computing offers an expanded view of the field that includes the traditional energy-motivated hardware viewpoint as well as the emerging application-motivated software approach. Collecting scattered knowledge into one coherent account, the book provides a compendium of both classical and recently developed results on reversible computing. It explores up-and-coming theories, techniques, and tools for the application of rever

  5. Reversibility of female sterilization.

    Science.gov (United States)

    Siegler, A M; Hulka, J; Peretz, A

    1985-04-01

    The discussion considers the current status of reversibility of sterilization in the US and describes clinical and experimental efforts for developing techniques designed for reversibility. It focuses on regret following sterilization, reversal potential of current sterilization techniques, patient selection, current reversal techniques, results of sterilization procedures, experimental approaches to reversal of current techniques of sterilization, and sterilization procedures devised for reversibility, in humans and in animals. Request is the 1st stage of reversal, but a request for sterilization reversal (SR) does not always mean regret for a decision made at the time. Frequently it is a wish to restore fertility because life circumstances have changed after a sterilization that was ppropriate at the time it was performed. Schwyhart and Kutner reviewed 22 studies published between 1949-69 in which they found that the percentage of patients regretting the procedure ranged from 1.3-15%. Requests for reversal remain low in most countries, but if sterilization becomes a more popular method of contraception, requests will also increase. The ideal operation considered as a reversaible method of sterilization should include an easy, reliable outpatient method of tubal occlusion with miniml risk or patient discomfort that subsequently could be reversed without the need for a major surgical intervention. Endoscopic methods have progressed toward the 1st objective. A recent search of the literature uncovered few series of SR of more than 50 cases. The 767 operations found were analyzed with regard to pregnancy outcome. The precent of live births varied from 74-78.8%, and the occurance of tubal pregnancies ranged from 1.7-6.5%. All of the confounding variables in patient selection and small numbers of reported procedures preclude any conclusion about the different techniques or the number of operations that give a surgeon a level of expertise. Few authors classify their

  6. Quantum reverse hypercontractivity

    Energy Technology Data Exchange (ETDEWEB)

    Cubitt, Toby [Department of Computer Science, University College London, London, United Kingdom and Centre for Quantum Information and Foundations, DAMTP, University of Cambridge, Cambridge (United Kingdom); Kastoryano, Michael [NBIA, Niels Bohr Institute, University of Copenhagen, 2100 Copenhagen (Denmark); Montanaro, Ashley [School of Mathematics, University of Bristol, Bristol (United Kingdom); Temme, Kristan [Institute for Quantum Information and Matter, California Institute of Technology, Pasadena, California 91125 (United States)

    2015-10-15

    We develop reverse versions of hypercontractive inequalities for quantum channels. By generalizing classical techniques, we prove a reverse hypercontractive inequality for tensor products of qubit depolarizing channels. We apply this to obtain a rapid mixing result for depolarizing noise applied to large subspaces and to prove bounds on a quantum generalization of non-interactive correlation distillation.

  7. Atrioventricular Pacemaker Lead Reversal

    Directory of Open Access Journals (Sweden)

    Mehmet K Aktas, MD

    2007-01-01

    Full Text Available During cardiac surgery temporary epicardial atrial and ventricular leads are placed in case cardiac pacing is required postoperatively. We present the first reported series of patients with reversal of atrioventricular electrodes in the temporary pacemaker without any consequent deleterious hemodynamic effect. We review the electrocardiographic findings and discuss the findings that lead to the discovery of atrioventricular lead reversal.

  8. A 3D model of crustal magnetization at the Pinacate Volcanic Field, NW Sonora, Mexico

    Science.gov (United States)

    García-Abdeslem, Juan; Calmus, Thierry

    2015-08-01

    The Pinacate Volcanic Field (PVF) is located near the western border of the southern Basin and Range province, in the State of Sonora NW Mexico, and within the Gulf of California Extensional Province. This volcanic field contains the shield volcano Santa Clara, which mainly consists of basaltic to trachytic volcanic rocks, and reaches an altitude of 1200 m. The PVF disrupts a series of discontinuous ranges of low topographic relief aligned in a NW direction, which consist mainly of Proterozoic metamorphic rocks and Proterozoic through Paleogene granitoids. The PVF covers an area of approximately 60 by 55 km, and includes more than 400 well-preserved cinder cones and vents and eight maar craters. It was active from about 1.7 Ma until about 13 ka. We have used the ages and magnetic polarities of the volcanic rocks, along with mapped magnetic anomalies and their inverse modeling to determine that the Pinacate Volcanic Field was formed during two volcanic episodes. The oldest one built the Santa Clara shield volcano of basaltic and trachytic composition, and occurred during the geomagnetic Matuyama Chron of reverse polarity, which also includes the normal polarity Jaramillo and Olduvai Subchrons, thus imprinting both normal and reverse magnetization in the volcanic products. The younger Pinacate series of basaltic composition represents monogenetic volcanic activity that extends all around the PVF and occurred during the subsequent geomagnetic Brunhes Chron of normal polarity. Magnetic anomalies toward the north of the Santa Clara volcano are the most intense in the PVF, and their inverse modeling indicates the presence of a large subsurface body magnetized in the present direction of the geomagnetic field. This suggests that the magma chambers at depth cooled below the Curie temperature during the Brunhes Chron.

  9. Quaternary magnetic excursions recorded in marine sediments.

    Science.gov (United States)

    Channell, J. E. T.

    2017-12-01

    This year is the golden (50th) anniversary of the first documentation of a magnetic excursion, the Laschamp excursion in volcanics from the Chaine des Puys (Bonhommet and Babkine, 1967). The first recording of an excursion in sediments was from the Blake Outer Ridge (Smith and Foster, 1969). Magnetic excursions are directional aberrations of the geomagnetic field apparently involving short-lived reversal of the main dipole field. They have durations of a few kyrs, and are therefore rarely recorded in sediments with mean sedimentation rates Palma), and 670 ka (Osaka Bay), implying at least 11 excursions in the Brunhes Chron. For the Matuyama Chron, excursions have been recorded in marine sediments at 868 ka (Kamikatsura?), 932 ka (Santa Rosa), 1051 ka (Intra-Jaramillo), 1115 ka (Punaruu), 1255 ka (Bjorn), 1476 ka (Gardar), 1580 ka (Gilsa), and 2737 ka (Porcupine). Excursions coincide with minima in relative paleointensity (RPI) records. Ages are from correlation of excursion records to oxygen isotope records in the same cores, and ice-volume calibration of the oxygen isotope template. The marine sediment record of excursions, combined with independent documentation of excursions in lavas with Ar/Ar age control, is progressively strengthening our knowledge of the excursion inventory in the Quaternary, and enhancing the importance of excursions and RPI in Quaternary stratigraphy.

  10. An algebra of reversible computation.

    Science.gov (United States)

    Wang, Yong

    2016-01-01

    We design an axiomatization for reversible computation called reversible ACP (RACP). It has four extendible modules: basic reversible processes algebra, algebra of reversible communicating processes, recursion and abstraction. Just like process algebra ACP in classical computing, RACP can be treated as an axiomatization foundation for reversible computation.

  11. Sex reversal in vertebrates

    OpenAIRE

    2016-01-01

    This special topic issue of Sexual Development gives an overview of sex reversal in vertebrates, from fishes naturally changing their sex, to rodents escaping the mammalian SRY-determining system. It offers eight up-to-date reviews on specific subjects in sex reversal, considering fishes, amphibians, reptiles, birds, marsupials, and placental mammals, including humans. The broad scope of represented animals makes this ideal for students and researchers, especially those interested in the...

  12. On thermodynamic and microscopic reversibility

    International Nuclear Information System (INIS)

    Crooks, Gavin E

    2011-01-01

    The word 'reversible' has two (apparently) distinct applications in statistical thermodynamics. A thermodynamically reversible process indicates an experimental protocol for which the entropy change is zero, whereas the principle of microscopic reversibility asserts that the probability of any trajectory of a system through phase space equals that of the time reversed trajectory. However, these two terms are actually synonymous: a thermodynamically reversible process is microscopically reversible, and vice versa

  13. The age of the Steens reversal and the Columbia River Basalt Group

    Science.gov (United States)

    Jarboe, Nicholas A.; Coe, Robert S.; Renne, Paul R.; Glen, Jonathan M. G.

    2010-01-01

    The Columbia River Basalt Group (CRBG) eruptions have a well-defined relative magnetostratigraphy but have not been definitively correlated to the geomagnetic polarity time scale. 40Ar/39Ar ages are presented from lavas erupted in the R0 through N1magnetozones of the CRBG and in the transition between R0 and N0. Four ages from transitionally magnetized lava flows at Steens Mountain, Catlow Peak, and Poker Jim Ridge with a weighted mean age 16.58 ± 0.10 Ma1 and the more precise age 16.654 ± 0.025 Ma of the normally magnetized Oregon Canyon tuff at the top of the Catlow Peak section show that the oldest CRBG magnetozone (R0) correlates with the C5Cr chron. Bayesian statistical analysis applied to data from four flows at Catlow Peak (using the mean age of the Steens reversal) gives a best and preferred age of the Steens reversal of 16.73 + 0.13/−0.08 Ma (95% confidence). Depending on the geomagnetic polarity time scale model, the eruption rate from N0 through R2 (0.34–0.45 Ma in the middle and the bulk of the CRBG emplacement) averaged 0.30–0.41 km3/a and peaked at a rate 1 1/2 to 4 1/2 times higher during R2.

  14. Reversible Communicating Processes

    Directory of Open Access Journals (Sweden)

    Geoffrey Brown

    2016-02-01

    Full Text Available Reversible distributed programs have the ability to abort unproductive computation paths and backtrack, while unwinding communication that occurred in the aborted paths. While it is natural to assume that reversibility implies full state recovery (as with traditional roll-back recovery protocols, an interesting alternative is to separate backtracking from local state recovery. For example, such a model could be used to create complex transactions out of nested compensable transactions where a programmer-supplied compensation defines the work required to "unwind" a transaction. Reversible distributed computing has received considerable theoretical attention, but little reduction to practice; the few published implementations of languages supporting reversibility depend upon a high degree of central control. The objective of this paper is to demonstrate that a practical reversible distributed language can be efficiently implemented in a fully distributed manner. We discuss such a language, supporting CSP-style synchronous communication, embedded in Scala. While this language provided the motivation for the work described in this paper, our focus is upon the distributed implementation. In particular, we demonstrate that a "high-level" semantic model can be implemented using a simple point-to-point protocol.

  15. Economic impact of reversion

    International Nuclear Information System (INIS)

    2005-01-01

    Estimations of the Norwegian hydropower production and various reversion models' market value have been made. The value of the Norwegian hydropower production until 01.01.2007 is estimated to about Nok 289 billion after taxes, or about 2,42 Nok/kWh medium production, given an expected future electricity price of around 0,25 Nok/kWh and a discount rate at 6,5 percent in nominal terms after taxes. The estimate is slightly above the level of prices for Norwegian hydropower plants in the last 8-10 years. The value of reversion in private plants which today have a limited licence time is estimated to Nok 5,5 billion. The value of reversion in public-owned Norwegian hydropower plants are about Nok 21 billion with a 60 year licence period from 01.01.2007, and about 12 billion for 75 years (ml)

  16. Evidence from lava flows for complex polarity transitions: The new composite Steens Mountain reversal record

    Science.gov (United States)

    Jarboe, Nicholas A.; Coe, Robert S.; Glen, Jonathan M. G.

    2011-01-01

    Geomagnetic polarity transitions may be significantly more complex than are currently depicted in many sedimentary and lava-flow records. By splicing together paleomagnetic results from earlier studies at Steens Mountain with those from three newly studied sections of Oregon Plateau flood basalts at Catlow Peak and Poker Jim Ridge 70–90 km to the southeast and west, respectively, we provide support for this interpretation with the most detailed account of a magnetic field reversal yet observed in volcanic rocks. Forty-five new distinguishable transitional (T) directions together with 30 earlier ones reveal a much more complex and detailed record of the 16.7 Ma reversed (R)-to-normal (N) polarity transition that marks the end of Chron C5Cr. Compared to the earlier R-T-N-T-N reversal record, the new record can be described as R-T-N-T-N-T-R-T-N. The composite record confirms earlier features, adds new west and up directions and an entire large N-T-R-T segment to the path, and fills in directions on the path between earlier directional jumps. Persistent virtual geomagnetic pole (VGP) clusters and separate VGPs have a preference for previously described longitudinal bands from transition study compilations, which suggests the presence of features at the core–mantle boundary that influence the flow of core fluid and distribution of magnetic flux. Overall the record is consistent with the generalization that VGP paths vary greatly from reversal to reversal and depend on the location of the observer. Rates of secular variation confirm that the flows comprising these sections were erupted rapidly, with maximum rates estimated to be 85–120 m ka−1 at Catlow and 130–195 m ka−1 at Poker Jim South. Paleomagnetic poles from other studies are combined with 32 non-transitional poles found here to give a clockwise rotation of the Oregon Plateau of 11.4°± 5.6° with respect to the younger Columbia River Basalt Group flows to the north and 14.5°± 4.6° with respect

  17. Reversible deep disposal

    International Nuclear Information System (INIS)

    2009-10-01

    This presentation, given by the national agency of radioactive waste management (ANDRA) at the meeting of October 8, 2009 of the high committee for the nuclear safety transparency and information (HCTISN), describes the concept of deep reversible disposal for high level/long living radioactive wastes, as considered by the ANDRA in the framework of the program law of June 28, 2006 about the sustainable management of radioactive materials and wastes. The document presents the social and political reasons of reversibility, the technical means considered (containers, disposal cavities, monitoring system, test facilities and industrial prototypes), the decisional process (progressive development and blocked off of the facility, public information and debate). (J.S.)

  18. Thermosensory reversal effect quantified

    NARCIS (Netherlands)

    Bergmann Tiest, W.M.; Kappers, A.M.L.

    2008-01-01

    At room temperature, some materials feel colder than others due to differences in thermal conductivity, heat capacity and geometry. When the ambient temperature is well above skin temperature, the roles of 'cold' and 'warm' materials are reversed. In this paper, this effect is quantified by

  19. Thermosensory reversal effect quantified

    NARCIS (Netherlands)

    Bergmann Tiest, W.M.; Kappers, A.M.L.

    2008-01-01

    At room temperature, some materials feel colder than others due to differences in thermal conductivity, heat capacity and geometry. When the ambient temperature is well above skin temperature, the roles of ‘cold’ and ‘warm’ materials are reversed. In this paper, this effect is quantified by

  20. Time reversal communication system

    Science.gov (United States)

    Candy, James V.; Meyer, Alan W.

    2008-12-02

    A system of transmitting a signal through a channel medium comprises digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. The channel medium may be air, earth, water, tissue, metal, and/or non-metal.

  1. Engineering Encounters: Reverse Engineering

    Science.gov (United States)

    McGowan, Veronica Cassone; Ventura, Marcia; Bell, Philip

    2017-01-01

    This column presents ideas and techniques to enhance your science teaching. This month's issue shares information on how students' everyday experiences can support science learning through engineering design. In this article, the authors outline a reverse-engineering model of instruction and describe one example of how it looked in our fifth-grade…

  2. Sex Reversal in Birds.

    Science.gov (United States)

    Major, Andrew T; Smith, Craig A

    2016-01-01

    Sexual differentiation in birds is controlled genetically as in mammals, although the sex chromosomes are different. Males have a ZZ sex chromosome constitution, while females are ZW. Gene(s) on the sex chromosomes must initiate gonadal sex differentiation during embryonic life, inducing paired testes in ZZ individuals and unilateral ovaries in ZW individuals. The traditional view of avian sexual differentiation aligns with that expounded for other vertebrates; upon sexual differentiation, the gonads secrete sex steroid hormones that masculinise or feminise the rest of the body. However, recent studies on naturally occurring or experimentally induced avian sex reversal suggest a significant role for direct genetic factors, in addition to sex hormones, in regulating sexual differentiation of the soma in birds. This review will provide an overview of sex determination in birds and both naturally and experimentally induced sex reversal, with emphasis on the key role of oestrogen. We then consider how recent studies on sex reversal and gynandromorphic birds (half male:half female) are shaping our understanding of sexual differentiation in avians and in vertebrates more broadly. Current evidence shows that sexual differentiation in birds is a mix of direct genetic and hormonal mechanisms. Perturbation of either of these components may lead to sex reversal. © 2016 S. Karger AG, Basel.

  3. Elastomers with Reversible Nanoporosity

    DEFF Research Database (Denmark)

    Szewczykowski, Piotr Przemyslaw; Andersen, K.; Schulte, Lars

    2009-01-01

    nanostructure and displays liquid-filled cavities. Upon several cycles of swelling and drying the cavities open and close in a reversible fashion. When exposed to a nonsolvent, the material remains collapsed. This discriminating behavior of liquid-material interaction holds potential for the use...

  4. Reversed field pinch diagnostics

    International Nuclear Information System (INIS)

    Weber, P.G.

    1986-01-01

    The Reversed Field Pinch (RFP) is a toroidal, axisymmetric magnetic confinement configuration characterized by a magnetic field configuration in which the toroidal magnetic field is of similar strength to the poloidal field, and is reversed at the edge compared to the center. The RFP routinely operates at high beta, and is a strong candidate for a compact fusion device. Relevant attributes of the configuration will be presented, together with an overview of present and planned experiments and their diagnostics. RFP diagnostics are in many ways similar to those of other magnetic confinement devices (such as tokamaks); these lectures will point out pertinent differences, and will present some diagnostics which provide special insights into unique attributes of the RFP

  5. Posterior Reversible Encephalopathy (PRES)

    International Nuclear Information System (INIS)

    Moron E, Fanny E; Diaz Marchan, Pedro

    2005-01-01

    The Posterior Reversible Encephalopathy Syndrome (PRES) is a clinical Syndrome composed of cephalea, alteration in vision and convulsions, usually observed in patients with sudden elevation of arterial pressure. The imagenologic evidence shows reversible vasogenic brain edema without stroke. Its location is predominantly posterior; it affects the cortex and the subcortical white matter of the occipital, parietal and temporal lobes. The treatment with antihypertensive drugs and the removing of immunosupressor medication are generally associated with complete neurological recovery; this is reflected also in the images which return to their basal condition. The untreated hypertension, on the other side, can result in a progressive defect of the autoregulation system of the central nervous system with cerebral hemorrhage, irreversible brain stroke, coma and death

  6. Reversible infantile mitochondrial diseases.

    Science.gov (United States)

    Boczonadi, Veronika; Bansagi, Boglarka; Horvath, Rita

    2015-05-01

    Mitochondrial diseases are usually severe and progressive conditions; however, there are rare forms that show remarkable spontaneous recoveries. Two homoplasmic mitochondrial tRNA mutations (m.14674T>C/G in mt-tRNA(Glu)) have been reported to cause severe infantile mitochondrial myopathy in the first months of life. If these patients survive the first year of life by extensive life-sustaining measures they usually recover and develop normally. Another mitochondrial disease due to deficiency of the 5-methylaminomethyl-2-thiouridylate methyltransferase (TRMU) causes severe liver failure in infancy, but similar to the reversible mitochondrial myopathy, within the first year of life these infants may also recover completely. Partial recovery has been noted in some other rare forms of mitochondrial disease due to deficiency of mitochondrial tRNA synthetases and mitochondrial tRNA modifying enzymes. Here we summarize the clinical presentation of these unique reversible mitochondrial diseases and discuss potential molecular mechanisms behind the reversibility. Understanding these mechanisms may provide the key to treatments of potential broader relevance in mitochondrial disease, where for the majority of the patients no effective treatment is currently available.

  7. Positioning paper on reversibility

    International Nuclear Information System (INIS)

    2016-01-01

    After having recalled the legal framework adopted in 2006 for the deep geological storage of radioactive wastes, and briefly introduced the concept of reversibility, this publication presents the principle of geological storage, presents high and medium level and long life wastes, highlights the ethical necessity to deal with these radioactive wastes, outlines that geological storage is the generally admitted and adopted solution at the international level, and presents additional means implemented for radioactive waste management. It presents the Cigeo project as the technical answer to the issue of radioactive waste storage, describes the Cigeo development process, its current status and its development planning, and justifies the choice of this technical solution, notably from an ethical point of view. It addresses the issue of reversibility and proposes an overview of the various tools and means which aim at guaranteeing this reversibility. Appendices propose figures illustrating the Cigeo project and its development process, and a rather detailed Power Point presentation of the project by the ANDRA (history, object, planning, installations, and so on)

  8. Status of time reversal invariance

    International Nuclear Information System (INIS)

    Henley, E.M.

    1989-01-01

    Time Reversal Invariance is introduced, and theories for its violation are reviewed. The present experimental and theoretical status of Time Reversal Invariance and tests thereof will be presented. Possible future tests will be discussed. 30 refs., 2 figs., 1 tab

  9. Introduction to time reversal theory

    International Nuclear Information System (INIS)

    Henley, E.M.

    1987-01-01

    Theory and reaction mechanisms relevant to time reversal invariance are reviewed. Consequences of time reversal invariance are presented under the headings of CP tests, electromagnetic moments, weak emissions or absorptions, and scattering reactions. 8 refs., 4 figs

  10. Reverse polarity magnetized melt rocks from the Chicxulub impact structure, Yucatan Peninsula, Mexico

    Science.gov (United States)

    Urrutia-Fucugauchi, Jaime; Marin, Luis E.; Sharpton, Virgil L.; Quezada, Juan Manuel

    1993-03-01

    Further paleomagnetic data for core samples of melt rock recovered in the Petroleos Mexicanos (PEMEX) exploratory wells within the Chicxulub structure, northern Yucatan peninsula, Mexico are reported. A previous report by Sharpton showed that the rocks studied contain high iridium levels and shocked breccia clasts, and an Ar-40/Ar-39 age of 65.2 plus or minus 0.4 Ma. The geomagnetic polarity determined for two samples is reverse (R) and was correlated with chron 29R that includes the K/T boundary. Our present analysis is based on two samples from each of three clasts of the melt rock from PEMEX well Y6-N17 (1295 to 1299 m b.s.l.). This study concentrates on the vectorial nature and stability of the remanence (NRM), the magnetic mineralogy and remanence carriers (i.e., the reliability and origin of the record), and on the implications (correlation with expected paleolatitude and polarity). The relative orientation of the drill core samples with respect to the horizontal is known. Samples were stable under alternating field (AF) and thermal treatments, and after removal of a small component they exhibited single-vectorial behavior. The characteristic remanence inclinations show small dispersion and a mean value (-43 deg) in close agreement with the expected inclination and paleolatitude (derived from the North American apparent polar wander path). Isothermal remenence (IRM) acquisition experiments, Lowrie-Fuller tests, coercivity and unblocking temperature spectra of NRM and saturation IRM, susceptibility and Q-coefficient analyses, and the single-component nature indicate a dominant mineralogy of iron-rich titanomagnetites with single or pseduo-single domain states. The stable characteristic magnetization may be interpreted as a result of shock heating of the rock at the time of formation of the inpact structure and its polarity, age, and paleolatitude are consistent with a time about the K/T boundary.

  11. The Causes of Preference Reversal.

    OpenAIRE

    Tversky, Amos; Slovic, Paul; Kahneman, Daniel

    1990-01-01

    Observed preference reversal cannot be adequately explained by violations of independence, the reduction axiom, or transitivity. The primary cause of preference reversal is the failure of procedure invariance, especially the overpricing of low-probability, high-payoff bets. This result violates regret theory and generalized (nonindependent) utility models. Preference reversal and a new reversal involving time preferences are explained by scale compatibility, which implies that payoffs are wei...

  12. Geomagnetic Field During a Reversal

    Science.gov (United States)

    Heirtzler, J. R.

    2003-01-01

    It has frequently been suggested that only the geomagnetic dipole, rather than higher order poles, reverse during a geomagnetic field reversal. Under this assumption the geomagnetic field strength has been calculated for the surface of the Earth for various steps of the reversal process. Even without an eminent a reversal of the field, extrapolation of the present secular change (although problematic) shows that the field strength may become zero in some geographic areas within a few hundred years.

  13. A Study on Reverse Logistics

    OpenAIRE

    Reddy, Dhananjaya

    2011-01-01

    In the competitive world of manufacturing, companies are often searching for new ways to improve their process, customer satisfaction and stay ahead in the game with their competitors. Reverse logistics has been considered a strategy to bring these things to life for the past decade or so. This thesis work tries to shed some light on the basics of reverse logistics and how reverse logistics can be used as a management strategy. This paper points out the fundamentals of reverse logistics and l...

  14. Geomagnetic Reversals during the Phanerozoic.

    Science.gov (United States)

    McElhinny, M W

    1971-04-09

    An antalysis of worldwide paleomagnetic measurements suggests a periodicity of 350 x 10(6) years in the polarity of the geomagnetic field. During the Mesozoic it is predominantly normal, whereas during the Upper Paleozoic it is predominantly reversed. Although geomagnetic reversals occur at different rates throughout the Phanerozoic, there appeaars to be no clear correlation between biological evolutionary rates and reversal frequency.

  15. Reversal Strategies for NOACs

    DEFF Research Database (Denmark)

    Husted, Steen; Verheugt, Freek; Comuth, Willemijn

    2015-01-01

    , coagulation factor concentrates or NOAC-specific antidotes could be used. Coagulation factor concentrates can be used in patients with haemophilia and to reverse the effect of VKAs but, in NOAC-treated patients, results are inconsistent and these agents could potentially have pro-thrombotic effects. Specific...... antidotes for NOACs are expected to be on the market soon. Phase III clinical trials with a humanized antibody fragment directed against dabigatran (idarucizumab) and recombinant, modified factor Xa (andexanet alfa) are ongoing. A molecule (aripazine) with broad activity against various anticoagulants...

  16. Reversible brazing process

    Science.gov (United States)

    Pierce, Jim D.; Stephens, John J.; Walker, Charles A.

    1999-01-01

    A method of reversibly brazing surfaces together. An interface is affixed to each surface. The interfaces can be affixed by processes such as mechanical joining, welding, or brazing. The two interfaces are then brazed together using a brazing process that does not defeat the surface to interface joint. Interfaces of materials such as Ni-200 can be affixed to metallic surfaces by welding or by brazing with a first braze alloy. The Ni-200 interfaces can then be brazed together using a second braze alloy. The second braze alloy can be chosen so that it minimally alters the properties of the interfaces to allow multiple braze, heat and disassemble, rebraze cycles.

  17. Reversibly Bistable Flexible Electronics

    KAUST Repository

    Alfaraj, Nasir

    2015-05-01

    Introducing the notion of transformational silicon electronics has paved the way for integrating various applications with silicon-based, modern, high-performance electronic circuits that are mechanically flexible and optically semitransparent. While maintaining large-scale production and prototyping rapidity, this flexible and translucent scheme demonstrates the potential to transform conventionally stiff electronic devices into thin and foldable ones without compromising long-term performance and reliability. In this work, we report on the fabrication and characterization of reversibly bistable flexible electronic switches that utilize flexible n-channel metal-oxide-semiconductor field-effect transistors. The transistors are fabricated initially on rigid (100) silicon substrates before they are peeled off. They can be used to control flexible batches of light-emitting diodes, demonstrating both the relative ease of scaling at minimum cost and maximum reliability and the feasibility of integration. The peeled-off silicon fabric is about 25 µm thick. The fabricated devices are transferred to a reversibly bistable flexible platform through which, for example, a flexible smartphone can be wrapped around a user’s wrist and can also be set back to its original mechanical position. Buckling and cyclic bending of such host platforms brings a completely new dimension to the development of flexible electronics, especially rollable displays.

  18. The influence of sea-level changes on tropical coastal lowlands; the Pleistocene Coropina Formation, Suriname

    Science.gov (United States)

    Wong, Th. E.; de Kramer, R.; de Boer, P. L.; Langereis, C.; Sew-A-Tjon, J.

    2009-04-01

    The Pleistocene Coropina Formation largely constitutes the Old Coastal Plain of Suriname. It is exposed fully only in open-pit bauxite mines in the central coastal plain as part of the unconsolidated overburden of Paleocene-Eocene bauxites. This study deals with the stratigraphy, sedimentology and chronology of this formation, and is based on a study in the recently closed Lelydorp-III bauxite mine operated by N.V. BHP Billiton Maatschappij Suriname. The Coropina Formation consists of the Para and Lelydorp Members. We present a detailed lithological subdivision of these members. In the Para Member, four units are discerned which are grouped in two transgressive cycles, both ranging upward from terrestrial towards chenier and coastal mudflat deposits reflecting glacio-eustatic sea-level changes. The sandy sediments represent fluviatile and beach-bar (chenier) deposits, and were supplied by rivers from the Precambrian basement and to a lesser extent by westward longshore coastal drift. Clays, largely derived from the Amazon River and transported alongshore over the shelf, were deposited in extensive coastal mudflats. The Lelydorp Member, also comprising four units, represents a depositional system that is closely comparable to the recent Suriname coastal setting, i.e., a lateral and vertical alternation of mudflat and chenier deposits formed over a period characterised by more or less constant sea level. Palaeomagnetic data indicate a dominantly reversed magnetic polarity in the Para Member, whereas the Lelydorp Member shows a normal magnetic polarity with a minor reversed polarity overprint. The reversed polarities of the Para Member exclude a Brunhes Chron (0.78-0.0 Ma) age, and thus assign it to the Matuyama Chron (2.58-0.78 Ma). This implies that the Coropina Formation is much older than hitherto assumed, and that one or more (long-term) hiatuses are not recognizable in the lithological succession.

  19. Reversible posterior leukoencephalopathy syndrome

    International Nuclear Information System (INIS)

    Lee, Eun Ja; Yu, Won Jong; Ahn, Kook Jin; Jung, So Lyung; Lee, Yeon Soo; Kim, Ji Chang; Kang, Si Won; Song, Chang Joon; Song, Soon-Young; Koo, Ja Hong; Kim, Man Deuk

    2001-01-01

    To review reversible posterior leukoencephalopathy syndrome. We reviewed 22 patients (M:F=3:19; age, 17-46 years) with the characteristic clinical and imaging features of reversible posterior leukoencephalopathy syndrome. All underwent brain MRI, and in three cases both CT and MRI were performed. In one, MRA was obtained, and in eleven, follow-up MR images were obtained. We evaluated the causes of this syndrome, its clinical manifestations, and MR findings including the locations of lesions, the presence or absence of contrast enhancement, and the changes seen at follow-up MRI. Of the 22 patients, 13 had eclampsia (six during pregnancy and seven during puerperium). Four were receiving immunosuppressive therapy (three, cyclosporine ; one, FK 506). Four suffered renal failure and one had complicated migraine. The clinical manifestations included headache (n=12), visual disturbance (n=13), seizure (n=15), focal neurologic sign (n=3), and altered mental status (n=2). Fifteen patients had hypertension and the others normotension. MRI revealed that lesions were bilateral (n=20) or unilateral (n=2). In all patients the lesion was found in the cortical and subcortical areas of the parieto-occipital lobes ; other locations were the basal ganglia (n=9), posterior temporal lobe (n=8), frontal lobe (n=5), cerebellum (n=5), pons (n=2), and thalamus (n=1). All lesions were of high signal intensity on T2-weighted images, and of iso to low intensity on T1-weighted images. One was combined with acute hematoma in the left basal ganglia. In eight of 11 patients who underwent postcontrast T1-weighted MRI, there was no definite enhancement ; in one, enhancement was mild, and in tow, patchy. CT studies showed low attenuation, and MRA revealed mild vasospasm. The symptoms of all patients improved. Follow-up MRI in nine of 11 patients depicted complete resolution of the lesions ; in two, small infarctions remained but the extent of the lesions had decreased. Reversible posterior

  20. Reversible posterior leukoencephalopathy syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Ja; Yu, Won Jong; Ahn, Kook Jin; Jung, So Lyung; Lee, Yeon Soo; Kim, Ji Chang; Kang, Si Won [The Catholic Univ. of Korea, Taejon (Korea, Republic of); Song, Chang Joon [Chungnam National Univ. School of Medicine, Cheonju (Korea, Republic of); Song, Soon-Young; Koo, Ja Hong [Kwandong Univ. College of Medicine, Myungji Hospital, Seoul (Korea, Republic of); Kim, Man Deuk [College of Medicine Pochon CHA Univ., Seoul (Korea, Republic of)

    2001-10-01

    To review reversible posterior leukoencephalopathy syndrome. We reviewed 22 patients (M:F=3:19; age, 17-46 years) with the characteristic clinical and imaging features of reversible posterior leukoencephalopathy syndrome. All underwent brain MRI, and in three cases both CT and MRI were performed. In one, MRA was obtained, and in eleven, follow-up MR images were obtained. We evaluated the causes of this syndrome, its clinical manifestations, and MR findings including the locations of lesions, the presence or absence of contrast enhancement, and the changes seen at follow-up MRI. Of the 22 patients, 13 had eclampsia (six during pregnancy and seven during puerperium). Four were receiving immunosuppressive therapy (three, cyclosporine ; one, FK 506). Four suffered renal failure and one had complicated migraine. The clinical manifestations included headache (n=12), visual disturbance (n=13), seizure (n=15), focal neurologic sign (n=3), and altered mental status (n=2). Fifteen patients had hypertension and the others normotension. MRI revealed that lesions were bilateral (n=20) or unilateral (n=2). In all patients the lesion was found in the cortical and subcortical areas of the parieto-occipital lobes ; other locations were the basal ganglia (n=9), posterior temporal lobe (n=8), frontal lobe (n=5), cerebellum (n=5), pons (n=2), and thalamus (n=1). All lesions were of high signal intensity on T2-weighted images, and of iso to low intensity on T1-weighted images. One was combined with acute hematoma in the left basal ganglia. In eight of 11 patients who underwent postcontrast T1-weighted MRI, there was no definite enhancement ; in one, enhancement was mild, and in tow, patchy. CT studies showed low attenuation, and MRA revealed mild vasospasm. The symptoms of all patients improved. Follow-up MRI in nine of 11 patients depicted complete resolution of the lesions ; in two, small infarctions remained but the extent of the lesions had decreased. Reversible posterior

  1. Reverse osmosis application studies

    International Nuclear Information System (INIS)

    Golomb, A.

    1982-02-01

    To assess the feasibility of applying reverse osmosis (RO) and ultrafiltration (UF) for effective treatment of process and waste streams from operations at Ontario Hydro's thermal and nuclear stations, an extensive literature survey has been carried out. It is concluded that RO is not at present economic for pretreatment of Great Lakes water prior to ion exchange demineralization for boiler makeup. Using both conventional and novel commercial membrane modules, RO pilot studies are recommended for treatment of boiler cleaning wastes, fly ash leachates, and flue gas desulphurization scrubber discharges for removal of heavy metals. Volume reduction and decontamination of nuclear station low-level active liquid waste streams by RO/UF also appear promising. Research programmes are proposed

  2. Reverse photoacoustic standoff spectroscopy

    Science.gov (United States)

    Van Neste, Charles W [Kingston, TN; Senesac, Lawrence R [Knoxville, TN; Thundat, Thomas G [Knoxville, TN

    2011-04-12

    A system and method are disclosed for generating a reversed photoacoustic spectrum at a greater distance. A source may emit a beam to a target and a detector measures signals generated as a result of the beam being emitted on the target. By emitting a chopped/pulsed light beam to the target, it may be possible to determine the target's optical absorbance by monitoring the intensity of light collected at the detector at different wavelengths. As the wavelength of light is changed, the target may absorb or reject each optical frequency. Rejection may increase the intensity at the sensing element and absorption may decrease the intensity. Accordingly, an identifying spectrum of the target may be made with the intensity variation of the detector as a function of illuminating wavelength.

  3. Reverse Osmosis Optimization

    Energy Technology Data Exchange (ETDEWEB)

    McMordie Stoughton, Kate; Duan, Xiaoli; Wendel, Emily M.

    2013-08-26

    This technology evaluation was prepared by Pacific Northwest National Laboratory on behalf of the U.S. Department of Energy’s Federal Energy Management Program (FEMP). ¬The technology evaluation assesses techniques for optimizing reverse osmosis (RO) systems to increase RO system performance and water efficiency. This evaluation provides a general description of RO systems, the influence of RO systems on water use, and key areas where RO systems can be optimized to reduce water and energy consumption. The evaluation is intended to help facility managers at Federal sites understand the basic concepts of the RO process and system optimization options, enabling them to make informed decisions during the system design process for either new projects or recommissioning of existing equipment. This evaluation is focused on commercial-sized RO systems generally treating more than 80 gallons per hour.¬

  4. Reverse Osmosis Optimization

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-08-01

    This technology evaluation was prepared by Pacific Northwest National Laboratory on behalf of the U.S. Department of Energy’s Federal Energy Management Program (FEMP). The technology evaluation assesses techniques for optimizing reverse osmosis (RO) systems to increase RO system performance and water efficiency. This evaluation provides a general description of RO systems, the influence of RO systems on water use, and key areas where RO systems can be optimized to reduce water and energy consumption. The evaluation is intended to help facility managers at Federal sites understand the basic concepts of the RO process and system optimization options, enabling them to make informed decisions during the system design process for either new projects or recommissioning of existing equipment. This evaluation is focused on commercial-sized RO systems generally treating more than 80 gallons per hour.

  5. Sex Reversal in Amphibians.

    Science.gov (United States)

    Flament, Stéphane

    2016-01-01

    Amphibians have been widely used to study developmental biology due to the fact that embryo development takes place independently of the maternal organism and that observations and experimental approaches are easy. Some amphibians like Xenopus became model organisms in this field. In the first part of this article, the differentiation of the gonads in amphibians and the mechanisms governing this process are reviewed. In the second part, the state of the art about sex reversal, which can be induced by steroid hormones in general and by temperature in some species, is presented. Also information about pollutants found in the environment that could interfere with the development of the amphibian reproductive apparatus or with their reproductive physiology is given. Such compounds could play a part in the amphibian decline, since in the wild, many amphibians are endangered species. © 2016 S. Karger AG, Basel.

  6. 49 CFR 230.89 - Reverse gear.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Reverse gear. 230.89 Section 230.89 Transportation... Reversing Gear § 230.89 Reverse gear. (a) General provisions. Reverse gear, reverse levers, and quadrants... quadrant. Proper counterbalance shall be provided for the valve gear. (b) Air-operated power reverse gear...

  7. Field reversal experiments (FRX)

    International Nuclear Information System (INIS)

    Linford, R.K.; Armstrong, W.T.; Platts, D.A.; Sherwood, E.G.

    1978-01-01

    The equilibrium, confinement, and stability properties of the reversed-field configuration (RFC) are being studied in two theta-pinch facilities. The RFC is an elongated toroidal plasma confined in a purely poloidal field geometry. The open field lines of the linear theta pinch support the closed-field RFC much like the vertical field centers the toroidal plasma in a tokamak. Depending on stability and confinement properties, the RFC might be used to greatly reduce the axial losses in linear fusion devices such as mirrors, theta pinches, and liners. The FRX systems produce RFC's with a major radius R = 2-6 cm, minor radius a approximately 2 cm, and a total length l approximately 35 cm. The observed temperatures are T/sub e/ approximately 100 eV and T/sub i/ = 150-350 eV with a peak density n approximately 2 x 10 15 cm -3 . After the plasma reaches equilibrium, the RFC remains stable for up to 30 μs followed by the rapid growth of the rotational m = 2 instability, which terminates the confinement. During the stable equilibrium, the particle and energy confinement times are more than 10 times longer than in an open-field system. The behavior of the m = 2 mode qualitatively agrees with the theoretically predicted instability for rotational velocities exceeding some critical value

  8. Field reversal experiments (FRX)

    International Nuclear Information System (INIS)

    Linford, R.K.; Armstrong, W.T.; Platts, D.A.; Sherwood, E.G.

    1979-01-01

    The equilibrium, confinement, and stability properties of the reversed-field configuration (RFC) are being studied in two theta-pinch facilities. The RFC is an elongated toroidal plasma confined in a purely poloidal field geometry. The open field lines of the linear theta pinch support the closed-field RFC much like the vertical field centres the toroidal plasma in a tokamak. Depending on stability and confinement properties, the RFC might be used to greatly reduce the axial losses in linear fusion devices such as mirrors, theta pinches, and liners. The FRX systems produce RFCs with a major radius R=2-6cm, a minor radius a approximately 2cm, and a total length l approximately 35cm. The observed temperatures are Tsub(e) approximately 100eV and Tsub(i)=150-350eV with a peak density n approximately 2x10 15 cm -3 . After the plasma has reached equilibrium, the RFC remains stable for up to 30μs, followed by the rapid growth of the rotational m=2 instability, which terminates the confinement. During the stable equilibrium, the particle and energy confinement times are more than 10 times longer than in an open-field system. The behaviour of the m=2 mode agrees qualitatively with the theoretically predicted instability for rotational velocities exceeding some critical value. (author)

  9. Network Routing Using the Network Tasking Order, a Chron Approach

    Science.gov (United States)

    2015-03-26

    Network traffic decision algorithms have been in place since the creation of the Internet. These algorithms are successful in redirecting...example, the fifth line indicates a location of 29° 42’ 48”N, 47° 31’ 06”E and a time-on target of 1200 Zulu on the 24th of January. A typical ATO is

  10. Towards a reversible functional language

    DEFF Research Database (Denmark)

    Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert

    2012-01-01

    /equality operator also simplifies inverse computation and program inversion. We discuss the advantages of a reversible functional language using example programs, including run-length encoding. Program inversion is seen to be as lightweight as for imperative reversible languages and realized by recursive descent...

  11. Reverse engineering of RFID devices

    NARCIS (Netherlands)

    Bokslag, W.

    2015-01-01

    This paper discusses the relevance and potential impact of both RFID and reverse engineering of RFID technology, followed by a discussion of common protocols and internals of RFID technology. The focus of the paper is on providing an overview of the different approaches to reverse engineering RFID

  12. How decision reversibility affects motivation

    NARCIS (Netherlands)

    Bullens, L.; van Harreveld, F.; Förster, J.; Higgins, T.E.

    2014-01-01

    The present research examined how decision reversibility can affect motivation. On the basis of extant findings, it was suggested that 1 way it could affect motivation would be to strengthen different regulatory foci, with reversible decision making, compared to irreversible decision making,

  13. Enzymatic reactions in reversed micelles

    NARCIS (Netherlands)

    Hilhorst, M.H.

    1984-01-01

    It has been recognised that enzymes in reversed micelles have potential for application in chemical synthesis. Before these expectations will be realised many problems must be overcome. This thesis deals with some of them.
    In Chapter 1 the present knowledge about reversed micelles and

  14. Reversible networks in supramolecular polymers

    NARCIS (Netherlands)

    Havermans - van Beek, D.J.M.

    2007-01-01

    Non–covalent interactions between low molecular weight polymers form the basis of supramolecular polymers. The material properties of such polymers are determined by the strength and lifetime of the non–covalent reversible interactions. Due to the reversibility of the interactions between the low

  15. Reverse genetics of avian metapneumoviruses

    Science.gov (United States)

    An overview of avian metapneumovirus (aMPV) infection in turkeys and development of a reverse genetics system for aMPV subgroup C (aMPV-C) virus will be presented. By using reverse genetics technology, we generated recombinant aMPV-C viruses containing a different length of glycoprotein (G) gene or...

  16. MODELS OF PROJECT REVERSE ENGINEERING

    Directory of Open Access Journals (Sweden)

    Віктор Володимирович ІВАНОВ

    2017-03-01

    Full Text Available Reverse engineering decided important scientific and technical problems of increasing the cost of the existing technical product by transforming it into a product with other features or design. Search ideas of the new application of existing products on the base of heuristic analysis were created. The concept of reverse engineering and its division into three types: conceptual, aggregate and complete was expanded. The use of heuristic methods for reverse engineering concept was showed. The modification model of Reverse engineering based on the model of РМВОК was developed. Our model includes two new phases: identification and transformation. At the identification phase, technical control is made. At the transformation phase, search heuristic idea of the new applied existing technical product was made. The model of execution phase that included heuristic methods, metrological equipment, and CAD/CAM/CAE program complex was created. The model that connected economic indicators of reverse engineering project was developed.

  17. What do reversible programs compute?

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Glück, Robert

    2011-01-01

    Reversible computing is the study of computation models that exhibit both forward and backward determinism. Understanding the fundamental properties of such models is not only relevant for reversible programming, but has also been found important in other fields, e.g., bidirectional model...... transformation, program transformations such as inversion, and general static prediction of program properties. Historically, work on reversible computing has focussed on reversible simulations of irreversible computations. Here, we take the viewpoint that the property of reversibility itself should...... are not strictly classically universal, but that they support another notion of universality; we call this RTM-universality. Thus, even though the RTMs are sub-universal in the classical sense, they are powerful enough as to include a self-interpreter. Lifting this to other computation models, we propose r...

  18. Fundamentals of reversible flowchart languages

    DEFF Research Database (Denmark)

    Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert

    2016-01-01

    Abstract This paper presents the fundamentals of reversible flowcharts. They are intended to naturally represent the structure and control flow of reversible (imperative) programming languages in a simple computation model, in the same way classical flowcharts do for conventional languages......, structured reversible flowcharts are as expressive as unstructured ones, as shown by a reversible version of the classic Structured Program Theorem. We illustrate how reversible flowcharts can be concretized with two example programming languages, complete with syntax and semantics: a low-level unstructured...... language and a high-level structured language. We introduce concrete tools such as program inverters and translators for both languages, which follow the structure suggested by the flowchart model. To further illustrate the different concepts and tools brought together in this paper, we present two major...

  19. The Geomagnetic Field During a Reversal

    Science.gov (United States)

    Heirtzler, James R.

    2003-01-01

    By modifying the IGRF it is possible to learn what may happen to the geomagnetic field during a geomagnetic reversal. If the entire IGRF reverses then the declination and inclination only reverse when the field strength is zero. If only the dipole component of the IGRF reverses a large geomagnetic field remains when the dipole component is zero and he direction of the field at the end of the reversal is not exactly reversed from the directions at the beginning of the reversal.

  20. How decision reversibility affects motivation.

    Science.gov (United States)

    Bullens, Lottie; van Harreveld, Frenk; Förster, Jens; Higgins, Tory E

    2014-04-01

    The present research examined how decision reversibility can affect motivation. On the basis of extant findings, it was suggested that 1 way it could affect motivation would be to strengthen different regulatory foci, with reversible decision making, compared to irreversible decision making, strengthening prevention-related motivation relatively more than promotion-related motivation. If so, then decision reversibility should have effects associated with the relative differences between prevention and promotion motivation. In 5 studies, we manipulated the reversibility of a decision and used different indicators of regulatory focus motivation to test these predictions. Specifically, Study 1 tested for differences in participants' preference for approach versus avoidance strategies toward a desired end state. In Study 2, we used speed and accuracy performance as indicators of participants' regulatory motivation, and in Study 3, we measured global versus local reaction time performance. In Study 4, we approached the research question in a different way, making use of the value-from-fit hypothesis (Higgins, 2000, 2002). We tested whether a fit between chronic regulatory focus and focus induced by the reversibility of the decision increased participants' subjective positive feelings about the decision outcome. Finally, in Study 5, we tested whether regulatory motivation, induced by decision reversibility, also influenced participants' preference in specific product features. The results generally support our hypothesis showing that, compared to irreversible decisions, reversible decisions strengthen a prevention focus more than a promotion focus. Implications for research on decision making are discussed.

  1. Supercritical fluid reverse micelle separation

    Science.gov (United States)

    Fulton, J.L.; Smith, R.D.

    1993-11-30

    A method of separating solute material from a polar fluid in a first polar fluid phase is provided. The method comprises combining a polar fluid, a second fluid that is a gas at standard temperature and pressure and has a critical density, and a surfactant. The solute material is dissolved in the polar fluid to define the first polar fluid phase. The combined polar and second fluids, surfactant, and solute material dissolved in the polar fluid is maintained under near critical or supercritical temperature and pressure conditions such that the density of the second fluid exceeds the critical density thereof. In this way, a reverse micelle system defining a reverse micelle solvent is formed which comprises a continuous phase in the second fluid and a plurality of reverse micelles dispersed in the continuous phase. The solute material is dissolved in the polar fluid and is in chemical equilibrium with the reverse micelles. The first polar fluid phase and the continuous phase are immiscible. The reverse micelles each comprise a dynamic aggregate of surfactant molecules surrounding a core of the polar fluid. The reverse micelle solvent has a polar fluid-to-surfactant molar ratio W, which can vary over a range having a maximum ratio W[sub o] that determines the maximum size of the reverse micelles. The maximum ratio W[sub o] of the reverse micelle solvent is then varied, and the solute material from the first polar fluid phase is transported into the reverse micelles in the continuous phase at an extraction efficiency determined by the critical or supercritical conditions. 27 figures.

  2. Reverse engineering for quality systems

    International Nuclear Information System (INIS)

    Nolan, A.J.

    1995-01-01

    When the age of software engineering began, many companies were faced with a problem of how to support the older, pre-software-engineering, programs. The techniques of reverse engineering and re-engineering were developed to bridge the gap between the past and the present. Although reverse engineering can be used for generating missing documentation, it can also be used as a means to demonstrate quality in these older programs. This paper presents, in the form of a case study, how Rolls-Royce and Associates Limited addressed the quality issues of reverse engineering and re-engineering. (author)

  3. Field reversal in mirror machines

    International Nuclear Information System (INIS)

    Pearlstein, L.D.; Anderson, D.V.; Boozer, A.H.

    1978-01-01

    This report discusses some of the physics issues anticipated in field-reversed mirrors. The effect of current cancellation due to electrons is described. An estimate is made of the required impurity level to maintain a field-reversed configuration. The SUPERLAYER code is used to simulate the high-β 2XIIB results, and favorable comparisons require inclusion of quasilinear RF turbulence. Impact of a quadrupole field on field-line closure and resonant transport is discussed. A simple self-consistent model of ion currents is presented. Conditions for stability of field-reversed configurations to E x B driven rotations are determined

  4. Zero field reversal probability in thermally assisted magnetization reversal

    Science.gov (United States)

    Prasetya, E. B.; Utari; Purnama, B.

    2017-11-01

    This paper discussed about zero field reversal probability in thermally assisted magnetization reversal (TAMR). Appearance of reversal probability in zero field investigated through micromagnetic simulation by solving stochastic Landau-Lifshitz-Gibert (LLG). The perpendicularly anisotropy magnetic dot of 50×50×20 nm3 is considered as single cell magnetic storage of magnetic random acces memory (MRAM). Thermally assisted magnetization reversal was performed by cooling writing process from near/almost Curie point to room temperature on 20 times runs for different randomly magnetized state. The results show that the probability reversal under zero magnetic field decreased with the increase of the energy barrier. The zero-field probability switching of 55% attained for energy barrier of 60 k B T and the reversal probability become zero noted at energy barrier of 2348 k B T. The higest zero-field switching probability of 55% attained for energy barrier of 60 k B T which corespond to magnetif field of 150 Oe for switching.

  5. A Typology of Reverse Innovation

    DEFF Research Database (Denmark)

    von Zedtwitz, Max; Corsi, Simone; Søberg, Peder Veng

    2015-01-01

    secondary market introduction, this study expands the espoused definition of reverse innovation beyond its market-introduction focus with reversals in the flow of innovation in the ideation and product development phases. Recognizing that each phase can take place in different geographical locations...... taking place in an emerging country. This analytical framework allows recasting of current research at the intersection between innovation and international business. Of the 10 reverse innovation flows, six are new and have not been covered in the literature to date. The study addresses questions......’s portfolio of global innovation competence and capability. The implications for management are concerned with internal and external resistance to reverse innovation. Most significantly, while greater recognition and power of innovation in formerly subordinate organizational units is inconvenient to some...

  6. Spontaneous direct and reverse osmosis

    International Nuclear Information System (INIS)

    Valitov, N.Kh.

    1996-01-01

    It has been ascertained experimentally that in the course of separation of CsCl, KCl, NaCl aqueous solutions by semi-permeable membrane from distilled water the direct and then reverse osmosis are observed. The same sequence is observed in case of separation of CsCl aqueous solutions from NaCl of different concentrations. The reason for the direct and reverse osmosis has been explained. 5 refs.; 3 figs. 1 tab

  7. Garbage collection for reversible functional languages

    DEFF Research Database (Denmark)

    Mogensen, Torben Ægidius

    2015-01-01

    Reversible languages are programming languages where all programs can run both forwards and backwards. Reversible functional languages have been proposed that use symmetric pattern matching and data construction. To be reversible, these languages require linearity: Every variable must be used...

  8. Vasectomy reversal: a clinical update

    Directory of Open Access Journals (Sweden)

    Abhishek P Patel

    2016-01-01

    Full Text Available Vasectomy is a safe and effective method of contraception used by 42-60 million men worldwide. Approximately 3%-6% of men opt for a vasectomy reversal due to the death of a child or divorce and remarriage, change in financial situation, desire for more children within the same marriage, or to alleviate the dreaded postvasectomy pain syndrome. Unlike vasectomy, vasectomy reversal is a much more technically challenging procedure that is performed only by a minority of urologists and places a larger financial strain on the patient since it is usually not covered by insurance. Interest in this procedure has increased since the operating microscope became available in the 1970s, which consequently led to improved patency and pregnancy rates following the procedure. In this clinical update, we discuss patient evaluation, variables that may influence reversal success rates, factors to consider in choosing to perform vasovasostomy versus vasoepididymostomy, and the usefulness of vasectomy reversal to alleviate postvasectomy pain syndrome. We also review the use of robotics for vasectomy reversal and other novel techniques and instrumentation that have emerged in recent years to aid in the success of this surgery.

  9. Reverse Knowledge Transfer in MNEs

    DEFF Research Database (Denmark)

    Mudambi, Ram; Piscitello, Lucia; Rabbiosi, Larissa

    2014-01-01

    a positive correlation with the extent of reverse knowledge transfers to the parent MNE. Relying on the headquarters-subsidiary view of the MNE, we argue that, beyond a point, increasing subsidiary innovativeness will be associated with lower reverse knowledge transfers. Further, we argue......It is now well recognized that multinational enterprises (MNEs) are differentiated networks wherein subsidiaries vary in terms of their ability to create new knowledge and competencies for their parent groups. In much of this theory, it is taken for granted that subsidiary innovativeness has...... that this relationship is sensitive to the subsidiary entry mode. Using data from a sample of 293 Italian subsidiaries, we find strong support for our hypotheses. In particular, our results confirm that the effect of subsidiary innovativeness on reverse knowledge transfers displays an inverted-U shape...

  10. Ice ages and geomagnetic reversals

    Science.gov (United States)

    Wu, Patrick

    1992-01-01

    There have been speculations on the relationship between climatic cooling and polarity reversals of the earth's magnetic field during the Pleistocene. Two of the common criticisms on this relationship have been the reality of these short duration geomagnetic events and the accuracy of their dates. Champion et al. (1988) have reviewed recent progress in this area. They identified a total of 10 short-duration polarity events in the last 1 Ma and 6 of these events have been found in volcanic rocks, which also have K-Ar dates. Supposing that the speculated relationship between climatic cooling and geomagnetic reversals actually exist, two mechanisms that assume climatic cooling causes short period magnetic reversals will be investigated. These two methods are core-mantle boundary topography and transfer of the rotational energy to the core.

  11. Reverse innovation in maternal health.

    Science.gov (United States)

    Firoz, Tabassum; Makanga, Prestige Tatenda; Nathan, Hannah L; Payne, Beth; Magee, Laura A

    2017-09-01

    Reverse innovation, defined as the flow of ideas from low- to high-income settings, is gaining traction in healthcare. With an increasing focus on value, investing in low-cost but effective and innovative solutions can be of mutual benefit to both high- and low-income countries. Reverse innovation has a role in addressing maternal health challenges in high-income countries by harnessing these innovative solutions for vulnerable populations especially in rural and remote regions. In this paper, we present three examples of 'reverse innovation' for maternal health: a low-cost, easy-to-use blood pressure device (CRADLE), a diagnostic algorithm (mini PIERS) and accompanying mobile app (PIERS on the Move), and a novel method for mapping maternal outcomes (MOM).

  12. Reverse Transfection Using Gold Nanoparticles

    Science.gov (United States)

    Yamada, Shigeru; Fujita, Satoshi; Uchimura, Eiichiro; Miyake, Masato; Miyake, Jun

    Reverse transfection from a solid surface has the potential to deliver genes into various types of cell and tissue more effectively than conventional methods of transfection. We present a method for reverse transfection using a gold colloid (GC) as a nanoscaffold by generating nanoclusters of the DNA/reagentcomplex on a glass surface, which could then be used for the regulation of the particle size of the complex and delivery of DNA into nuclei. With this method, we have found that the conjugation of gold nanoparticles (20 nm in particle size) to the pEGFP-N1/Jet-PEI complex resulted in an increase in the intensity of fluorescence of enhanced green fluorescent protein (EGFP) (based on the efficiency of transfection) from human mesenchymal stem cells (hMSCs), as compared with the control without GC. In this manner, we constructed a method for reverse transfection using GC to deliver genes into the cells effectively.

  13. Designing the Reverse Supply Chain

    DEFF Research Database (Denmark)

    Gobbi, Chiara

    2011-01-01

    Purpose – The purpose of this paper is to explore the impact of the product residual value (PRV) and the loss of value over time of returned products in the reverse supply chain configuration. It also examines whether or not the distinction of Fisher's functional and innovative products holds...... that allows for recapturing most of the PRV. These notions have then been tested by analyzing two reverse supply chains with a case study research methodology. Findings – The findings show that low PRV is associated with second-class recovery options (recycling and energy recovery) and that high PRV...... is associated with first-class recovery options (reconditioning and remarketing). When the recovery option is recycling, time is not relevant, the primary objective is cost reduction (efficiency), the chain is centralized, and actors and phases of the reverse chain are determined by the specificity...

  14. Reverse genetics with animal viruses. NSV reverse genetics

    International Nuclear Information System (INIS)

    Mebatsion, T.

    2005-01-01

    New strategies to genetically manipulate the genomes of several important animal pathogens have been established in recent years. This article focuses on the reverse genetics techniques, which enables genetic manipulation of the genomes of non-segmented negative-sense RNA viruses. Recovery of a negative-sense RNA virus entirely from cDNA was first achieved for rabies virus in 1994. Since then, reverse genetic systems have been established for several pathogens of medical and veterinary importance. Based on the reverse genetics technique, it is now possible to design safe and more effective live attenuated vaccines against important viral agents. In addition, genetically tagged recombinant viruses can be designed to facilitate serological differentiation of vaccinated animals from infected animals. The approach of delivering protective immunogens of different pathogens using a single vector was made possible with the introduction of the reverse genetics system, and these novel broad-spectrum vaccine vectors have potential applications in improving animal health in developing countries. (author)

  15. Marburg Virus Reverse Genetics Systems

    Directory of Open Access Journals (Sweden)

    Kristina Maria Schmidt

    2016-06-01

    Full Text Available The highly pathogenic Marburg virus (MARV is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses. Reverse genetics systems established for MARV have been used to study various aspects of the viral replication cycle, analyze host responses, image viral infection, and screen for antivirals. This article provides an overview of the currently established MARV reverse genetic systems based on minigenomes, infectious virus-like particles and full-length clones, and the research that has been conducted using these systems.

  16. Reverse Zymography: Overview and Pitfalls.

    Science.gov (United States)

    Sharma, Kanika; Bhattacharyya, Debasish

    2017-01-01

    Reverse zymography is a technique by which protease inhibitor(s) in a sample could be electrophoretically separated in a substrate-impregnated acrylamide gel and their relative abundance could be semi-quantified. The gel after electrophoresis is incubated with a protease when the impregnated substrate and all other proteins of the sample are degraded into small peptides except the inhibitor(s) that show clear bands against a white background. Since reverse zymography cannot distinguish between a protease inhibitor and a protein that is resistant against proteolysis, the results should be confirmed from inhibition of protease activity by solution state assay.

  17. Reverse hybrid total hip arthroplasty

    DEFF Research Database (Denmark)

    Wangen, Helge; Havelin, Leif I.; Fenstad, Anne M

    2017-01-01

    Background and purpose - The use of a cemented cup together with an uncemented stem in total hip arthroplasty (THA) has become popular in Norway and Sweden during the last decade. The results of this prosthetic concept, reverse hybrid THA, have been sparsely described. The Nordic Arthroplasty....... Patients and methods - From the NARA, we extracted data on reverse hybrid THAs from January 1, 2000 until December 31, 2013. 38,415 such hips were studied and compared with cemented THAs. The Kaplan-Meier method and Cox regression analyses were used to estimate the prosthesis survival and the relative risk...

  18. Reference counting for reversible languages

    DEFF Research Database (Denmark)

    Mogensen, Torben Ægidius

    2014-01-01

    inverses: Freeing a block of memory is done by running the allocation procedure backwards. Axelsen and Glück use this heap manager to sketch implementation of a simple reversible functional language where pattern matching a constructor is the inverse of construction, so pattern-matching implies......Modern programming languages and operating systems use heap memory that allows allocation and deallocation of memory to be decoupled, so they don't follow a stack discipline. Axelsen and Glück have presented a reversible heap manager where allocation and deallocation are each other's logical...

  19. A functional language for describing reversible logic

    DEFF Research Database (Denmark)

    Thomsen, Michael Kirkedal

    2012-01-01

    Reversible logic is a computational model where all gates are logically reversible and combined in circuits such that no values are lost or duplicated. This paper presents a novel functional language that is designed to describe only reversible logic circuits. The language includes high....... Reversibility of descriptions is guaranteed with a type system based on linear types. The language is applied to three examples of reversible computations (ALU, linear cosine transformation, and binary adder). The paper also outlines a design flow that ensures garbage- free translation to reversible logic...... circuits. The flow relies on a reversible combinator language as an intermediate language....

  20. CAPSULE REPORT: REVERSE OSMOSIS PROCESS

    Science.gov (United States)

    A failure analysis has been completed for the reverse osmosis (RO) process. The focus was on process failures that result in releases of liquids and vapors to the environment. The report includes the following: 1) A description of RO and coverage of the principles behind the proc...

  1. Time reversal and parity tests

    International Nuclear Information System (INIS)

    Terwilliger, K.

    1975-01-01

    A recent review by Henley discusses the present status of Time Reversal and Parity symmetry violations, and comments on the implications for high energy hadron scattering. This note will briefly summarize the situation with particular attention to the sizes of possible effects, relating them to experimental accuracy available or reasonably possible at the ZGS

  2. A Framework for Reverse Logistics

    NARCIS (Netherlands)

    M.P. de Brito (Marisa); R. Dekker (Rommert)

    2003-01-01

    textabstractReverse Logistics has been stretching out worldwide, involving all the layers of supply chains in various industry sectors. While some actors in the chain have been forced to take products back, others have pro-actively done so, attracted by the value in used products One way or the

  3. Reverse ventilation--perfusion mismatch

    International Nuclear Information System (INIS)

    Palmaz, J.C.; Barnett, C.A.; Reich, S.B.; Krumpe, P.E.; Farrer, P.A.

    1984-01-01

    Patients having lobar airway obstruction or consolidation usually have decreases of both ventilation and perfusion on lung scans. We report three patients in whom hypoxic vasoconstriction was apparently incomplete, resulting in a ''reversed'' ventilation-perfusion mismatch. Perfusion of the hypoxic lobe on the radionuclide scan was associated with metabolic alkalosis, pulmonary venous and pulmonary arterial hypertension in these patients

  4. Reverse amblyopia with atropine treatment.

    Science.gov (United States)

    Hainline, Bryan C; Sprunger, Derek C; Plager, David A; Neely, Daniel E; Guess, Matthew G

    2009-01-01

    Occlusion, pharmacologic pernalization and combined therapy have been documented in controlled studies to effectively treat amblyopia with few complications. However, there remain concerns about the effectiveness and complications when, as in this case, there are not standardized treatment protocols. A retrospective chart review of 133 consecutive patients in one community based ophthalmology practice treated for amblyopia was performed. Treatments evaluated were occlusion only, atropine penalization, and combination of occlusion and atropine. Reverse amblyopia was defined as having occured when the visual acuity of the sound eye was 3 LogMar units worse than visual acuity of the amblyopia eye after treatment. Improvement in vision after 6 months and 1 year of amblyopia therapy was similar among all three groups: 0.26 LogMar lines and 0.30 in the atropine group, 0.32 and 0.34 in the occlusion group, and 0.24 and 0.32 in the combined group. Eight (6%) patients demonstrated reverse amblyopia. The mean age of those who developed reverse amblyopia was 3.5 years, 1.5 years younger than the mean age of the study population, 7/8 had strabismic amblyopia, 6/8 were on daily atropine and had a mean refractive error of +4.77 diopters in the amblyopic eye and +5.06 diopters in the sound eye. Reverse amblyopia did not occur with occlusion only therapy. In this community based ophthalmology practice, atropine, patching, and combination therapy appear to be equally effective modalities to treat ambyopia. Highly hyperopic patients under 4 years of age with dense, strabismic amblyopia and on daily atropine appeared to be most at risk for development of reverse amblyopia.

  5. Magnetochronology and stratigraphy at Gran Dolina section, Atapuerca (Burgos, Spain).

    Science.gov (United States)

    Parés, J M; Pérez-González, A

    1999-01-01

    The Atapuerca Site (Burgos, N. Spain) is an extensive archaeological site which has yielded numerous human fossil remains. The Gran Dolina section, one of the open-air excavations and subject of this study, consists of a sedimentary infilling of 18 m thickness in a gallery originated by karstification of the host Cretaceous limestones. In this paper we present new stratigraphic and paleomagnetic evidence for the age and the sedimentary environment of the karst infilling where the archaeological site is located. Paleomagnetic dating places the hominids (Aurora stratum) in the Matuyama reversed Chron, hence before 780 ka. We also report evidence for a short normal polarity event at the bottom of the section that we speculate as being Jaramillo or Kamikatsura. The early and well-constrained date of the Atapuerca archaeological site, its location in the cul-de-sac we know as Europe, its stratigraphic context, the abundant fossil remains and the stone tool industry make it one of the most important localities for the question of the earliest human occupation in Europe. Copyright 1999 Academic Press.

  6. Reversal agents in anaesthesia and critical care

    Directory of Open Access Journals (Sweden)

    Nibedita Pani

    2015-01-01

    Full Text Available Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist. Reversal agents are defined as any drug used to reverse the effects of anaesthetics, narcotics or potentially toxic agents. The controversy on the routine reversal of neuromuscular blockade still exists. The advent of newer reversal agents like sugammadex have made the use of steroidal neuromuscular blockers like rocuronium feasible in rapid sequence induction situations. We made a review of the older reversal agents and those still under investigation for drugs that are regularly used in our anaesthesia practice.

  7. Reverse osmosis water purification system

    Science.gov (United States)

    Ahlstrom, H. G.; Hames, P. S.; Menninger, F. J.

    1986-01-01

    A reverse osmosis water purification system, which uses a programmable controller (PC) as the control system, was designed and built to maintain the cleanliness and level of water for various systems of a 64-m antenna. The installation operates with other equipment of the antenna at the Goldstone Deep Space Communication Complex. The reverse osmosis system was designed to be fully automatic; with the PC, many complex sequential and timed logic networks were easily implemented and are modified. The PC monitors water levels, pressures, flows, control panel requests, and set points on analog meters; with this information various processes are initiated, monitored, modified, halted, or eliminated as required by the equipment being supplied pure water.

  8. Trend towards reverse leach process

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    The South African gold mining industry is making notable strides in improving recovery methods for both gold and uranium with significant additions to profits because of higher efficiencies and reductions in costs in the recovery processes. The most notable step on the gold side recently is the adoption of the reverse leach process at Buffelsfontein and Western Deep Levels. This process was pioneered at Hartebeesfontein as far back as 1975 and when introduced there resulted in a two and a half per cent improvement in recovery efficiencies. The essence of reverse leaching under which the uranium is recovered before the gold is the fact that the gold partly coated with iron oxide or locked in uranite, is exposed to be recovered later by cyanidation

  9. Reversible evolution of charged ergoregions

    Energy Technology Data Exchange (ETDEWEB)

    Kokkotas, K.; Spyrou, N.

    1987-07-01

    The reversible evolution of a charged rotating ergoregion, due to the injection into it of particles with mass-energy and angular momentum, is studied systematically. As in the uncharged case, a bulge always forms on the outer boundary of the ergoregion due to the latter's angular momentum. The behavior of the bulge's position, relative to the black hole's rotation axis and equatorial plane, is studied, on the basis of the cosmic censorship hypothesis, during the ergoregion's reversible evolution. The range of the permitted values of the ergoregion's linear dimensions along the rotation axis and perpendicular to it is specified. Finally the differences with the evolution of an uncharged ergoregion are pointed out and discussed.

  10. Malware analysis and reverse engineering

    OpenAIRE

    Šváb, Martin

    2014-01-01

    Focus of this thesis is reverse engineering in information technology closely linked with the malware analysis. It explains fundamentals of IA-32 processors architecture and basics of operating system Microsoft Windows. Main part of this thesis is dedicated to the malware analysis, including description of creating a tool for simplification of static part of the analysis. In Conclusion various approaches to the malware analysis, which were described in previous part of the thesis, are practic...

  11. How to play Reverse Hex

    DEFF Research Database (Denmark)

    Toft, Bjarne; Hayward, Ryan B.; Henderson, Philip

    2012-01-01

    We present new results on how to play Reverse Hex, also known as Rex, or Misère Hex, on n × n boards. We give new proofs – and strengthened versions – of Lagarias and Sleator’s theorem (for n × n boards, each player can prolong the game until the board is full, so the first/second player can alwa...

  12. Theory of field reversed configurations

    International Nuclear Information System (INIS)

    Steinhauer, L.C.

    1990-01-01

    This final report surveys the results of work conducted on the theory of field reversed configurations. This project has spanned ten years, beginning in early 1980. During this period, Spectra Technology was one of the leading contributors to the advances in understanding FRC. The report is organized into technical topic areas, FRC formation, equilibrium, stability, and transport. Included as an appendix are papers published in archival journals that were generated in the course of this report. 33 refs

  13. Reverse engineering of integrated circuits

    Science.gov (United States)

    Chisholm, Gregory H.; Eckmann, Steven T.; Lain, Christopher M.; Veroff, Robert L.

    2003-01-01

    Software and a method therein to analyze circuits. The software comprises several tools, each of which perform particular functions in the Reverse Engineering process. The analyst, through a standard interface, directs each tool to the portion of the task to which it is most well suited, rendering previously intractable problems solvable. The tools are generally used iteratively to produce a successively more abstract picture of a circuit, about which incomplete a priori knowledge exists.

  14. Risperidone-induced reversible neutropenia.

    Science.gov (United States)

    Kattalai Kailasam, Vasanth; Chima, Victoria; Nnamdi, Uchechukwu; Sharma, Kavita; Shah, Kairav

    2017-01-01

    This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient's laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia.

  15. CONCEPTUAL ISSUES REGARDING REVERSE LOGISTICS

    Directory of Open Access Journals (Sweden)

    Ioana Olariu

    2013-12-01

    Full Text Available As the power of consumers is growing, the product return for customer service and customer retention has become a common practice in the competitive market, which propels the recent practice of reverse logistics in companies. Many firms attracted by the value available in the flow, have proactively participated in handling returned products at the end of their usefulness or from other parts of the product life cycle. Reverse logistics is the flow and management of products, packaging, components and information from the point of consumption to the point of origin. It is a collection of practices similar to those of supply chain management, but in the opposite direction, from downstream to upstream. It involves activities such as reuse, repair, remanufacture, refurbish, reclaim and recycle. For the conventional forward logistics systems, the flow starts upstream as raw materials, later as manufactured parts and components to be assembled and continues downstream to reach customers as final products to be disposed once they reach their economic or useful lives. In reverse logistics, the disposed products are pushed upstream to be repaired, remanufactured, refurbished, and disassembled into components to be reused or as raw material to be recycled for later use.

  16. SELECTED PROBLEMS OF REVERSE LOGISTICS IN POLAND

    OpenAIRE

    Agata Mesjasz-Lech

    2009-01-01

    This paper presents the essence of reverse logistics and directions of physical and information flows between logistic network partners. It also analyses effects of implementation of the principles of reverse logistics in Poland in the years 2004-2007

  17. Periodicity and Immortality in Reversible Computing

    OpenAIRE

    Kari , Jarkko; Ollinger , Nicolas

    2008-01-01

    Additional material available on the web at http://www.lif.univ-mrs.fr/~nollinge/rec/gnirut/; We investigate the decidability of the periodicity and the immortality problems in three models of reversible computation: reversible counter machines, reversible Turing machines and reversible one-dimensional cellular automata. Immortality and periodicity are properties that describe the behavior of the model starting from arbitrary initial configurations: immortality is the property of having at le...

  18. r-Universal reversible logic gates

    International Nuclear Information System (INIS)

    Vos, A de; Storme, L

    2004-01-01

    Reversible logic plays a fundamental role both in ultra-low power electronics and in quantum computing. It is therefore important to know which reversible logic gates can be used as building block for the reversible implementation of an arbitrary boolean function and which cannot

  19. THEORETICAL FRAMES FOR DESIGNING REVERSE LOGISTICS PROCESSES

    OpenAIRE

    Janusz K. Grabara; Sebastian Kot

    2009-01-01

    Logistics processes of return flow became more and more important in present business practice. Because of better customer satisfaction, environmental and financial aspects many enterprises deal with reverse logistics performance. The paper is a literature review focused on the design principles of reverse logistics processes Keywords: reverse logistics, designing.

  20. Prefix reversals on binary and ternary strings

    NARCIS (Netherlands)

    Hurkens, C.A.J.; van Iersel, L.J.J.; Keijsper, J.C.M.; Kelk, S.M.; Stougie, L.; Tromp, J.T.

    2007-01-01

    Given a permutation $\\pi$, the application of prefix reversal $f^{(i)}$ to $\\pi$ reverses the order of the first $i$ elements of $\\pi$. The problem of sorting by prefix reversals (also known as pancake flipping), made famous by Gates and Papadimitriou (Discrete Math., 27 (1979), pp. 47–57), asks

  1. Prefix reversals on binary and ternary strings

    NARCIS (Netherlands)

    Hurkens, C.A.J.; Iersel, van L.J.J.; Keijsper, J.C.M.; Kelk, S.M.; Stougie, L.; Tromp, J.T.

    2007-01-01

    Given a permutation $\\pi$, the application of prefix reversal $f^{(i)}$ to $\\pi$ reverses the order of the first $i$ elements of $\\pi$. The problem of sorting by prefix reversals (also known as pancake flipping), made famous by Gates and Papadimitriou (Discrete Math., 27 (1979), pp. 47–57), asks for

  2. Remote Whispering Applying Time Reversal

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Brian Eric [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-07-16

    The purpose of this project was to explore the use of time reversal technologies as a means for communication to a targeted individual or location. The idea is to have the privacy of whispering in one’s ear, but to do this remotely from loudspeakers not located near the target. Applications of this work include communicating with hostages and survivors in rescue operations, communicating imaging and operational conditions in deep drilling operations, monitoring storage of spent nuclear fuel in storage casks without wires, or clandestine activities requiring signaling between specific points. This technology provides a solution in any application where wires and radio communications are not possible or not desired. It also may be configured to self calibrate on a regular basis to adjust for changing conditions. These communications allow two people to converse with one another in real time, converse in an inaudible frequency range or medium (i.e. using ultrasonic frequencies and/or sending vibrations through a structure), or send information for a system to interpret (even allowing remote control of a system using sound). The time reversal process allows one to focus energy to a specific location in space and to send a clean transmission of a selected signal only to that location. In order for the time reversal process to work, a calibration signal must be obtained. This signal may be obtained experimentally using an impulsive sound, a known chirp signal, or other known signals. It may also be determined from a numerical model of a known environment in which the focusing is desired or from passive listening over time to ambient noise.

  3. Repeatable Reverse Engineering with PANDA

    Science.gov (United States)

    2015-12-08

    necessary layout information for the Android 2.3 and 4.2 SDK kernels. See Section IV-C for an example of the kind of deep reverse engineering of Android apps ...code re-use and simplifying complex analysis development. We demonstrate PANDA’s effectiveness via a number of use cases, including enabling an old but...continue to function. 2) Identify critical vulnerabilities . 3) Understand the true purpose and actions of code. It is common for legacy code to stop

  4. Corrosion protected reversing heat exchanger

    International Nuclear Information System (INIS)

    Zawierucha, R.

    1984-01-01

    A reversing heat exchanger of the plate and fin type having multiple aluminum parting sheets in a stacked arrangement with corrugated fins separating the sheets to form multiple flow paths, means for closing the ends of the sheets, an input manifold arrangement of headers for the warm end of of the exchanger and an output manifold arrangement for the cold end of the exchanger with the input air feed stream header and the waste gas exhaust header having an alloy of zinc and aluminum coated on the inside surface for providing corrosion protection to the stack

  5. Presbycusis: reversible with anesthesia drugs?

    Science.gov (United States)

    Kocher, Carl A

    2009-02-01

    Age-related hearing impairment, or presbycusis, is a degenerative condition not currently treatable by medication. It is therefore significant that the author, as a patient, experienced a reversal of high-frequency hearing loss during a 2-day period following abdominal surgery with general anesthesia. This report documents the surgery and the subsequent restoration of hearing, which was bilateral and is estimated to have exceeded 50dB at 4kHz. A possible role is noted for anesthetic agents such as lidocaine, propofol, or fentanyl. This experience may hold a clue for research toward the development of medical treatments for presbycusis.

  6. Field-reversed mirror reactor

    International Nuclear Information System (INIS)

    Carlson, G.A.

    1978-01-01

    The reactor design is a multicell arrangement wherein a series of field-reversed plasma layers are arranged along the axis of a long superconducting solenoid which provides the background magnetic field. Normal copper mirror coils and Ioffe bars placed at the first wall radius provide shallow axial and radial magnetic wells for each plasma layer. Each of 11 plasma layers requires the injection of 3.6 MW of 200 keV deuterium and tritium and produces 20 MW of fusion power. The reactor has a net electric output of 74 MWe and an estimated direct capital cost of $1200/kWe

  7. Kinematic reversal schemes for the geomagnetic dipole.

    Science.gov (United States)

    Levy, E. H.

    1972-01-01

    Fluctuations in the distribution of cyclonic convective cells, in the earth's core, can reverse the sign of the geomagnetic field. Two kinematic reversal schemes are discussed. In the first scheme, a field maintained by cyclones concentrated at low latitude is reversed by a burst of cyclones at high latitude. Conversely, in the second scheme, a field maintained predominantly by cyclones in high latitudes is reversed by a fluctuation consisting of a burst of cyclonic convection at low latitude. The precise fluid motions which produce the geomagnetic field are not known. However, it appears that, whatever the details are, a fluctuation in the distribution of cyclonic cells over latitude can cause a geomagnetic reversal.

  8. Theta, time reversal and temperature

    Energy Technology Data Exchange (ETDEWEB)

    Gaiotto, Davide [Perimeter Institute for Theoretical Physics,Waterloo, Ontario, N2L 2Y5 (Canada); Kapustin, Anton [Walter Burke Institute for Theoretical Physics, California Institute of Technology,Pasadena, CA 91125 (United States); Komargodski, Zohar [Department of Particle Physics and Astrophysics, Weizmann Institute of Science,Rehovot 76100 (Israel); Seiberg, Nathan [School of Natural Sciences, Institute for Advanced Study,Princeton, NJ 08540 (United States)

    2017-05-17

    SU(N) gauge theory is time reversal invariant at θ=0 and θ=π. We show that at θ=π there is a discrete ’t Hooft anomaly involving time reversal and the center symmetry. This anomaly leads to constraints on the vacua of the theory. It follows that at θ=π the vacuum cannot be a trivial non-degenerate gapped state. (By contrast, the vacuum at θ=0 is gapped, non-degenerate, and trivial.) Due to the anomaly, the theory admits nontrivial domain walls supporting lower-dimensional theories. Depending on the nature of the vacuum at θ=π, several phase diagrams are possible. Assuming area law for space-like loops, one arrives at an inequality involving the temperatures at which CP and the center symmetry are restored. We also analyze alternative scenarios for SU(2) gauge theory. The underlying symmetry at θ=π is the dihedral group of 8 elements. If deconfined loops are allowed, one can have two O(2)-symmetric fixed points. It may also be that the four-dimensional theory around θ=π is gapless, e.g. a Coulomb phase could match the underlying anomalies.

  9. Exercise prescription to reverse frailty.

    Science.gov (United States)

    Bray, Nick W; Smart, Rowan R; Jakobi, Jennifer M; Jones, Gareth R

    2016-10-01

    Frailty is a clinical geriatric syndrome caused by physiological deficits across multiple systems. These deficits make it challenging to sustain homeostasis required for the demands of everyday life. Exercise is likely the best therapy to reverse frailty status. Literature to date suggests that pre-frail older adults, those with 1-2 deficits on the Cardiovascular Health Study-Frailty Phenotype (CHS-frailty phenotype), should exercise 2-3 times a week, for 45-60 min. Aerobic, resistance, flexibility, and balance training components should be incorporated but resistance and balance activities should be emphasized. On the other hand, frail (CHS-frailty phenotype ≥ 3 physical deficits) older adults should exercise 3 times per week, for 30-45 min for each session with an emphasis on aerobic training. During aerobic, balance, and flexibility training, both frail and pre-frail older adults should work at an intensity equivalent to a rating of perceived exertion of 3-4 ("somewhat hard") on the Borg CR10 scale. Resistance-training intensity should be based on a percentage of 1-repetition estimated maximum (1RM). Program onset should occur at 55% of 1RM (endurance) and progress to higher intensities of 80% of 1RM (strength) to maximize functional gains. Exercise is the medicine to reverse or mitigate frailty, preserve quality of life, and restore independent functioning in older adults at risk of frailty.

  10. Theta, time reversal and temperature

    International Nuclear Information System (INIS)

    Gaiotto, Davide; Kapustin, Anton; Komargodski, Zohar; Seiberg, Nathan

    2017-01-01

    SU(N) gauge theory is time reversal invariant at θ=0 and θ=π. We show that at θ=π there is a discrete ’t Hooft anomaly involving time reversal and the center symmetry. This anomaly leads to constraints on the vacua of the theory. It follows that at θ=π the vacuum cannot be a trivial non-degenerate gapped state. (By contrast, the vacuum at θ=0 is gapped, non-degenerate, and trivial.) Due to the anomaly, the theory admits nontrivial domain walls supporting lower-dimensional theories. Depending on the nature of the vacuum at θ=π, several phase diagrams are possible. Assuming area law for space-like loops, one arrives at an inequality involving the temperatures at which CP and the center symmetry are restored. We also analyze alternative scenarios for SU(2) gauge theory. The underlying symmetry at θ=π is the dihedral group of 8 elements. If deconfined loops are allowed, one can have two O(2)-symmetric fixed points. It may also be that the four-dimensional theory around θ=π is gapless, e.g. a Coulomb phase could match the underlying anomalies.

  11. Optimized reversible binary-coded decimal adders

    DEFF Research Database (Denmark)

    Thomsen, Michael Kirkedal; Glück, Robert

    2008-01-01

    Abstract Babu and Chowdhury [H.M.H. Babu, A.R. Chowdhury, Design of a compact reversible binary coded decimal adder circuit, Journal of Systems Architecture 52 (5) (2006) 272-282] recently proposed, in this journal, a reversible adder for binary-coded decimals. This paper corrects and optimizes...... their design. The optimized 1-decimal BCD full-adder, a 13 × 13 reversible logic circuit, is faster, and has lower circuit cost and less garbage bits. It can be used to build a fast reversible m-decimal BCD full-adder that has a delay of only m + 17 low-power reversible CMOS gates. For a 32-decimal (128-bit....... Keywords: Reversible logic circuit; Full-adder; Half-adder; Parallel adder; Binary-coded decimal; Application of reversible logic synthesis...

  12. Kinetic Line Voronoi Operations and Their Reversibility

    DEFF Research Database (Denmark)

    Mioc, Darka; Anton, François; Gold, Christopher

    2010-01-01

    In Geographic Information Systems the reversibility of map update operations has not been explored yet. In this paper we are using the Voronoi based Quad-edge data structure to define reversible map update operations. The reversibility of the map operations has been formalised at the lowest level...... mechanisms and dynamic map visualisations. In order to use the reversibility within the kinetic Voronoi diagram of points and open oriented line segments, we need to assure that reversing the map commands will produce exactly the changes in the map equivalent to the previous map states. To prove...... that reversing the map update operations produces the exact reverse changes, we show an isomorphism between the set of complex operations on the kinetic Voronoi diagram of points and open oriented line segments and the sets of numbers of new / deleted Voronoi regions induced by these operations, and its...

  13. Reversal of diaschisis by zolpidem

    International Nuclear Information System (INIS)

    Claus, R.P.; Nel, H.W.; Sathekge, M.

    2004-01-01

    Full text: Introduction: Recent literature has reported on clinical improvement after zolpidem, a GABAergic anti insomnia drug, in brain injury and stroke patients. In this study, the effect of zolpidem on crossed cerebellar diaschisis was investigated in such patients. Method: Four patients with crossed cerebellar diaschisis after brain injury or stroke were investigated before and after application of 10 mg zolpidem by 99mTc HMPAO brain SPECT. Result: Apart from clinical improvements, 99mTc HMPAO brain SPECT studies showed reversal of the crossed cerebellar diaschisis and improvement of perfusion defects after zolpidem. Conclusion: 99mTc HMPAO brain SPECT may have a role to pre-select brain injury and stroke patients who will benefit clinically from zolpidem therapy. (author)

  14. Model of reverse steam generator

    International Nuclear Information System (INIS)

    Malasek, V.; Manek, O.; Masek, V.; Riman, J.

    1987-01-01

    The claim of Czechoslovak discovery no. 239272 is a model designed for the verification of the properties of a reverse steam generator during the penetration of water, steam-water mixture or steam into liquid metal flowing inside the heat exchange tubes. The design may primarily be used for steam generators with a built-in inter-tube structure. The model is provided with several injection devices configured in different heat exchange tubes, spaced at different distances along the model axis. The design consists in that between the pressure and the circumferential casings there are transverse partitions and that in one chamber consisting of the circumferential casings, pressure casing and two adjoining partitions there is only one passage of the injection device through the inter-tube space. (Z.M.). 1 fig

  15. Time-averaged paleomagnetic field at the equator: Complete data and results from the Galapagos Islands, Ecuador

    Science.gov (United States)

    Gromme, Sherman; Mankinen, Edward A.; Prévot, Michel

    2010-01-01

    We present here the complete paleomagnetic laboratory results from a collection of approximately 1500 oriented cores from all 16 of the Galapagos Islands, Ecuador, collected by Allan Cox in 1964–1965 but nearly all previously unpublished. The islands are located in the eastern Pacific Ocean within 1.4° of latitude from the equator and range in age from historically erupted to 3 Ma, mostly determined by published K-Ar and 3He isotopic dating. The number of sites collected on each island ranges from 1 to 28, for a total of 186. After combining duplicate site mean directions, 149 are used for an overall mean direction and 8 represent excursions and one reversal path. Divided by geomagnetic polarity chron, 110 site means are Brunhes or Jaramillo (normal polarity), 27 are Matuyama (reversed polarity), and 12 are Gauss (both polarities). We have completed the magnetic cleaning that was commenced in the late 1960s. Secondary (mostly viscous) magnetizations were nearly all removed by alternating field demagnetization at 10 mT. We have used the so-called blanket cleaning method, generally at 10 mT. All sites were in basalt flows and gave good paleomagnetic results; none was rejected in toto, and only a few core specimens were magnetically unsatisfactory. Nearly all sites had eight independently oriented cores, and within-site angular standard deviations of directions range from 1° to 8°. We used both Fisher and Bingham statistics to analyze the data and found that many of the direction populations are strongly elongate along the paleomagnetic meridian, while the corresponding virtual pole (VGP) populations are essentially circularly distributed. The paleomagnetic poles, calculated as the means of VGPs, are as follows: Brunhes and Jaramillo, north latitude = 86.9°, east longitude = 245.1°, and 95% confidence radius A95 = 1.9°; Matuyama, latitude = 87.2°, longitude = 158.2°, and A95 = 3.8°; Gauss, latitude = 83.0°, longitude = 204.7°, and A95 = 7.0°. These

  16. Reversible arithmetic logic unit for quantum arithmetic

    DEFF Research Database (Denmark)

    Thomsen, Michael Kirkedal; Glück, Robert; Axelsen, Holger Bock

    2010-01-01

    This communication presents the complete design of a reversible arithmetic logic unit (ALU) that can be part of a programmable reversible computing device such as a quantum computer. The presented ALU is garbage free and uses reversible updates to combine the standard reversible arithmetic...... and logical operations in one unit. Combined with a suitable control unit, the ALU permits the construction of an r-Turing complete computing device. The garbage-free ALU developed in this communication requires only 6n elementary reversible gates for five basic arithmetic-logical operations on two n......-bit operands and does not use ancillae. This remarkable low resource consumption was achieved by generalizing the V-shape design first introduced for quantum ripple-carry adders and nesting multiple V-shapes in a novel integrated design. This communication shows that the realization of an efficient reversible...

  17. Principles of a reversible programming language

    DEFF Research Database (Denmark)

    Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert

    2008-01-01

    The principles of reversible programming languages are explicated and illustrated with reference to the design of a high-level imperative language, Janus. The fundamental properties for such languages include backward as well as forward determinism and reversible updates of data. The unique design...... languages, and demonstrate this for Janus. We show the practicality of the language by implementation of a reversible fast Fourier transform. Our results indicate that the reversible programming paradigm has fundamental properties that are relevant to many different areas of computer science....... features of the language include explicit post-condition assertions, direct access to an inverse semantics and the possibility of clean (i.e., garbage-free) computation of injective functions. We suggest the clean simulation of reversible Turing machines as a criterion for computing strength of reversible...

  18. Securing Biometric Images using Reversible Watermarking

    OpenAIRE

    Thampi, Sabu M.; Jacob, Ann Jisma

    2011-01-01

    Biometric security is a fast growing area. Protecting biometric data is very important since it can be misused by attackers. In order to increase security of biometric data there are different methods in which watermarking is widely accepted. A more acceptable, new important development in this area is reversible watermarking in which the original image can be completely restored and the watermark can be retrieved. But reversible watermarking in biometrics is an understudied area. Reversible ...

  19. Combining or Separating Forward and Reverse Logistics

    DEFF Research Database (Denmark)

    Herbert-Hansen, Zaza Nadja Lee; Larsen, Samuel; Nielsen, Anders

    2018-01-01

    Purpose – While forward logistics handles and manages the flow of goods downstream in the supply chain from suppliers to customers, reverse logistics (RL) manages the flow of returned goods upstream. A firm can combine reverse logistics with forward logistics, keep the flows separated, or choose......-research addresses intra-RL issues while the relationship between forward and reverse logistics is under-researched. This paper contributes to RL-theory by identifying the contextual factors that determine the most advantageous relationship between forward and reverse logistics, and proposes a novel decision making...

  20. Time reversal and the neutron

    International Nuclear Information System (INIS)

    Chupp, T. E.; Cooper, R. L.; Coulter, K. P.; Freedman, S. J.; Fujikawa, B. K.; Jones, G. L.; Garcia, A.; Mumm, H. P.; Nico, J. S.; Thompson, A. K.; Trull, C.; Wietfeldt, F. E.; Wilkerson, J. F.

    2013-01-01

    We have measured the triple correlation D n >/J n ·(β e x p-hat ν ) with a polarized cold-neutron beam (Mumm et al., Phys Rev Lett 107:102301, 2011; Chupp et al., Phys Rev C 86:035505, 2012). A non-zero value of D can arise due to parity-even-time-reversal-odd interactions that imply CP violation. Final-state effects also contribute to D at the level of 10  − 5 and can be calculated with precision of 1 % or better. The D coefficient is uniquely sensitive to the imaginary part of the ratio of axial-vector and vector beta-decay amplitudes as well as to scalar and tensor interactions that could arise due to beyond-Standard-Model physics. Over 300 million proton-electron coincidence events were used in a blind analysis with the result D = [ − 0.94±1.89 (stat)±0.97(sys)]×10  − 4 . Assuming only vector and axial vector interactions in beta decay, our result can be interpreted as a measure of the phase of the axial-vector coupling relative to the vector coupling, φ AV = 180.012 ° ± 0.028 °. This result also improves constrains on certain non-VA interactions.

  1. Reverse transcriptase inhibitors as microbicides.

    Science.gov (United States)

    Lewi, Paul; Heeres, Jan; Ariën, Kevin; Venkatraj, Muthusamy; Joossens, Jurgen; Van der Veken, Pieter; Augustyns, Koen; Vanham, Guido

    2012-01-01

    The CAPRISA 004 study in South Africa has accelerated the development of vaginal and rectal microbicides containing antiretrovirals that target specific enzymes in the reproduction cycle of HIV, especially reverse transcriptase inhibitors (RTI). In this review we discuss the potential relevance of HIV-1 RTIs as microbicides, focusing in the nucleotide RTI tenofovir and six classes of nonnucleoside RTIs (including dapivirine, UC781, urea and thiourea PETTs, DABOs and a pyrimidinedione). Although tenofovir and dapivirine appear to be most advanced in clinical trials as potential microbicides, several issues remain unresolved, e.g., the importance of nonhuman primates as a "gatekeeper" for clinical trials, the emergence and spread of drug-resistant mutants, the combination of microbicides that target different phases of viral reproduction and the accessibility to microbicides in low-income countries. Thus, here we discuss the latest research on RTI as microbicides in the light of the continuing spread of the HIV pandemic from the point of view of medicinal chemistry, virological, and pharmaceutical studies.

  2. Reversible hypothyroidism and Whipple's disease

    Directory of Open Access Journals (Sweden)

    Tran Huy A

    2006-05-01

    Full Text Available Abstract Background The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroidism is unusual and here forth is such a case due to infection of the thyroid gland with Tropheryma whippleii, Whipple disease. Case presentation A 45 year-old female presented with symptoms and signs consistent with primary hypothyroidism, which was also confirmed biochemically. Her response to thyroxine replacement therapy was poor however, requiring a significantly elevated amount. Further investigation revealed the presence of Whipple's disease involving the gastrointestinal trace and possibly the thyroid gland. Her thyroxine requirement decreased drastically following appropriate antimicrobial therapy for Whipple's disease to the extent that it was ceased. Thyrotropin releasing hormone testing in the steady state suggested there was diminished thyroid reserve due to Whipple's disease. Conclusion This is the first ante-mortem case report studying the possible involvement of the thyroid gland by Whipple's disease. Despite the normalization of her thyroid function test biochemically after antibiotic therapy, there is diminished thyroid reserve thus requiring close and regular monitoring.

  3. Time reversal and the neutron

    Energy Technology Data Exchange (ETDEWEB)

    Chupp, T. E., E-mail: chupp@umich.edu; Cooper, R. L.; Coulter, K. P. [Univeristy of Michigan (United States); Freedman, S. J.; Fujikawa, B. K. [University of California and Lawrence Berkeley Laboratory (United States); Jones, G. L. [Hamilton College (United States); Garcia, A. [University of Washington (United States); Mumm, H. P.; Nico, J. S.; Thompson, A. K. [National Institute of Standards and Technology (United States); Trull, C.; Wietfeldt, F. E. [Tulane University (United States); Wilkerson, J. F. [University of North Carolina (United States); Collaboration: emiT II Collaboration

    2013-03-15

    We have measured the triple correlation D/J{sub n}{center_dot}({beta}{sub e} x p-hat{sub {nu}}) with a polarized cold-neutron beam (Mumm et al., Phys Rev Lett 107:102301, 2011; Chupp et al., Phys Rev C 86:035505, 2012). A non-zero value of D can arise due to parity-even-time-reversal-odd interactions that imply CP violation. Final-state effects also contribute to D at the level of 10{sup - 5} and can be calculated with precision of 1 % or better. The D coefficient is uniquely sensitive to the imaginary part of the ratio of axial-vector and vector beta-decay amplitudes as well as to scalar and tensor interactions that could arise due to beyond-Standard-Model physics. Over 300 million proton-electron coincidence events were used in a blind analysis with the result D = [ - 0.94{+-}1.89 (stat){+-}0.97(sys)] Multiplication-Sign 10{sup - 4}. Assuming only vector and axial vector interactions in beta decay, our result can be interpreted as a measure of the phase of the axial-vector coupling relative to the vector coupling, {phi}{sub AV} = 180.012 Degree-Sign {+-} 0.028 Degree-Sign . This result also improves constrains on certain non-VA interactions.

  4. New magnetostratigraphy for the Olduvai Subchron in the Koobi Fora Formation, northwest Kenya, with implications for early Homo

    Science.gov (United States)

    Lepre, Christopher J.; Kent, Dennis V.

    2010-02-01

    A problematic magnetostratigraphy for the Koobi Fora Formation has contributed to debates on the evolutionary implications for early hominin fossils. To address this, 50 independent samples distributed over a nearly 63-m-thick interval were collected from the lower-middle KBS Member type section in fossil collection Area 102, northeast Turkana Basin. Characteristic directions obtained by thermal demagnetization define a coherent magnetostratigraphy that is supported by alternating-field studies on 28 sister specimens and the prior tephrochronological framework. Two long polarity intervals were recognized, each 30-40 m in thickness, and interpreted as the upper part of the normal polarity Olduvai Subchron and the overlying reverse polarity Matuyama Chron. The end Olduvai consists of a normal-reverse-normal polarity sequence occurring over a thickness of at least 1 m but perhaps up to 5 m, suggesting that this subchron has a short reverse interval in its uppermost part. Such a fine-scale structure also has been reported from several other sites, like the Pliocene-Pleistocene boundary and point stratotype section at Vrica, Italy, which serves as a basis for formally delimiting three temporally discrete polarity subintervals for the Olduvai Subchron. These paleomagnetic results that place the upper boundary of the Olduvai at ˜ 48 m above the base of the KBS Member, coupled with published radioisotopic dates, firmly secure the age of partial cranium KNM-ER 3733 in the interval 1.78-1.48 Ma, with an interpolated age of ˜ 1.7 Ma, giving this fossil the most unambiguous numerical-age constraints, as compared to the oldest Homo cranial remains from Europe and Asia. Nonetheless, assured placement of the top of the Olduvai Subchron in the KBS Member is not sufficient in the face of other uncertainties to influence conventional interpretations of the timing and direction for the global dispersal of early Homo erectus.

  5. Multiple reversal olfactory learning in honeybees

    Directory of Open Access Journals (Sweden)

    Theo Mota

    2010-07-01

    Full Text Available In multiple reversal learning, animals trained to discriminate a reinforced from a non-reinforced stimulus are subjected to various, successive reversals of stimulus contingencies (e.g. A+ vs. B-, A- vs. B+, A+ vs. B-. This protocol is useful to determine whether or not animals learn to learn and solve successive discriminations faster (or with fewer errors with increasing reversal experience. Here we used the olfactory conditioning of proboscis extension reflex to study how honeybees Apis mellifera perform in a multiple reversal task. Our experiment contemplated four consecutive differential conditioning phases involving the same odors (A+ vs. B- to A- vs. B+ to A+ vs. B- to A- vs. B+. We show that bees in which the weight of reinforced or non-reinforced stimuli was similar mastered the multiple olfactory reversals. Bees which failed the task exhibited asymmetric responses to reinforced and non-reinforced stimuli, thus being unable to rapidly reverse stimulus contingencies. Efficient reversers did not improve their successive discriminations but rather tended to generalize their choice to both odors at the end of conditioning. As a consequence, both discrimination and reversal efficiency decreasedalong experimental phases. This result invalidates a learning-to-learn effect and indicates that bees do not only respond to the actual stimulus contingencies but rather combine these with an average of past experiences with the same stimuli.  

  6. Online Reverse Auctions for Procurement of Services

    NARCIS (Netherlands)

    U.L. Radkevitch (Uladzimir)

    2008-01-01

    textabstractOnline reverse auctions, in which a buyer seeks to select a supplier and suppliers compete for contracts by bidding online, revolutionized corporate procurement early this century. Shortly after they had been pioneered by General Electric, many companies rushed to adopt reverse auctions

  7. Vibrational dynamics of ice in reverse micelles

    NARCIS (Netherlands)

    Dokter, A.M.; Petersen, C.; Woutersen, S.; Bakker, H.J.

    2008-01-01

    he ultrafast vibrational dynamics of HDO:D2O ice at 180 K in anionic reverse micelles is studied by midinfrared femtosecond pump-probe spectroscopy. Solutions containing reverse micelles are cooled to low temperatures by a fast-freezing procedure. The heating dynamics of the micellar solutions is

  8. Reversible logic gates on Physarum Polycephalum

    International Nuclear Information System (INIS)

    Schumann, Andrew

    2015-01-01

    In this paper, we consider possibilities how to implement asynchronous sequential logic gates and quantum-style reversible logic gates on Physarum polycephalum motions. We show that in asynchronous sequential logic gates we can erase information because of uncertainty in the direction of plasmodium propagation. Therefore quantum-style reversible logic gates are more preferable for designing logic circuits on Physarum polycephalum

  9. Magnetic reversals from planetary dynamo waves.

    Science.gov (United States)

    Sheyko, Andrey; Finlay, Christopher C; Jackson, Andrew

    2016-11-24

    A striking feature of many natural dynamos is their ability to undergo polarity reversals. The best documented example is Earth's magnetic field, which has reversed hundreds of times during its history. The origin of geomagnetic polarity reversals lies in a magnetohydrodynamic process that takes place in Earth's core, but the precise mechanism is debated. The majority of numerical geodynamo simulations that exhibit reversals operate in a regime in which the viscosity of the fluid remains important, and in which the dynamo mechanism primarily involves stretching and twisting of field lines by columnar convection. Here we present an example of another class of reversing-geodynamo model, which operates in a regime of comparatively low viscosity and high magnetic diffusivity. This class does not fit into the paradigm of reversal regimes that are dictated by the value of the local Rossby number (the ratio of advection to Coriolis force). Instead, stretching of the magnetic field by a strong shear in the east-west flow near the imaginary cylinder just touching the inner core and parallel to the axis of rotation is crucial to the reversal mechanism in our models, which involves a process akin to kinematic dynamo waves. Because our results are relevant in a regime of low viscosity and high magnetic diffusivity, and with geophysically appropriate boundary conditions, this form of dynamo wave may also be involved in geomagnetic reversals.

  10. Reverse engineering of the robot base platform

    International Nuclear Information System (INIS)

    Anwar A Rahman; Azizul Rahman A Aziz; Mohd Arif Hamzah; Muhd Nor Atan; Fadil Ismail; Rosli Darmawan

    2009-01-01

    The robot base platform used to place the robotic arm version 2 was imported through a local company. The robot base platform is used as a reference for reverse egineering development for a smaller size robot. The paper will discuss the reverse engineering design process and parameters involved in the development of the robot base platform. (Author)

  11. Reverse logistics: A review of case studies

    NARCIS (Netherlands)

    Brito, de M.P.; Dekker, Rommert; Flapper, S.D.P.; Fleischmann, B.; Klose, A.

    2004-01-01

    This paper gives an overview of scientific literature that describes and discusses cases of reverse logistics activities in practice. Over sixty case studies are considered. Based on these studies we are able to indicate critical factors for the practice of reverse logistics. In addition we compare

  12. Reversal of laryngotracheal separation in paediatric patients.

    LENUS (Irish Health Repository)

    Young, Orla

    2012-02-01

    OBJECTIVE: Laryngotracheal separation (LTS) is an effective and reliable definitive treatment for intractable aspiration. A major advantage of this treatment for intractable aspiration is its\\' potential reversibility. Should the underlying disorder improve, a reversal of the procedure may be attempted. This has been successfully achieved in the adult population. To our knowledge, no previous cases have been reported of successful reversal of LTS in children. METHODS: A retrospective review from 2003 to 2010 identified four cases of intractable aspiration treated with LTS in our department. Two of these patients displayed objective evidence of sufficient recovery of their underlying aspiration to consider reversal. Patient selection for reversal was dependent upon successful oral intake for 9 months along with videofluoroscopic evidence of normal or minimally impaired swallow. RESULTS: Two children who were successfully treated for intractable aspiration with LTS demonstrated objective evidence of recovery sufficient to attempt reversal. Both children underwent successful surgical reversal of LTS using a cricotracheal resection with end-to-end anastamosis, similar to that used in treatment of subglottic stenosis. Both children can now tolerate oral diet and their speech and language development is in line with their overall developmental level. CONCLUSIONS: Laryngotracheal separation is an effective and reliable definitive treatment for intractable aspiration facilitating protection of the airway and allowing safe swallowing with unimpeded respiration, but with the major drawback of loss of phonation. To our knowledge, we document the first two cases of successful LTS reversal in children.

  13. Observation of the reversed current effect

    International Nuclear Information System (INIS)

    Jones, I.R.; Silawatshananai, C.

    1979-05-01

    The paper describes an observation of the reversed current effect, and its consequences, in a 'stabilized' Z-pinch. Magnetic probe measurements and holographic interferometry were used to follow the development of a reversed current layer and to pinpoint its location in the outer region of the pinched plasma column. The subsequent ejection of the outer plasma layer was observed using fast photography

  14. Magnetic reversals from planetary dynamo waves

    DEFF Research Database (Denmark)

    Sheyko, Andrey; Finlay, Chris; Jackson, Andrew

    2016-01-01

    A striking feature of many natural dynamos is their ability to undergo polarity reversals. The best documented example is Earth's magnetic field, which has reversed hundreds of times during its history. The origin of geomagnetic polarity reversals lies in a magnetohydrodynamic process that takes ...... to kinematic dynamo waves. Because our results are relevant in a regime of low viscosity and high magnetic diffusivity, and with geophysically appropriate boundary conditions, this form of dynamo wave may also be involved in geomagnetic reversals.......A striking feature of many natural dynamos is their ability to undergo polarity reversals. The best documented example is Earth's magnetic field, which has reversed hundreds of times during its history. The origin of geomagnetic polarity reversals lies in a magnetohydrodynamic process that takes...... place in Earth's core, but the precise mechanism is debated. The majority of numerical geodynamo simulations that exhibit reversals operate in a regime in which the viscosity of the fluid remains important, and in which the dynamo mechanism primarily involves stretching and twisting of field lines...

  15. Kronisk ileus efter iatrogen reversering af tyndtarmen

    DEFF Research Database (Denmark)

    Pedersen, Mark Ellebaek; Rahr, Hans B; Mahdi, Bassam

    2010-01-01

    We report a case of inadvertent reversal of the entire small intestine leading to severe complications and long-standing ileus. The clinical diagnosis was confirmed by magnetic resonance imaging and laparotomy. The patient was cured by surgical re-reversal of the bowel. Care should be taken to ma...... the bowel ends when multiple simultaneous bowel resections are performed....

  16. Probabilistic Reversible Automata and Quantum Automata

    OpenAIRE

    Golovkins, Marats; Kravtsev, Maksim

    2002-01-01

    To study relationship between quantum finite automata and probabilistic finite automata, we introduce a notion of probabilistic reversible automata (PRA, or doubly stochastic automata). We find that there is a strong relationship between different possible models of PRA and corresponding models of quantum finite automata. We also propose a classification of reversible finite 1-way automata.

  17. Designing Novel Quaternary Quantum Reversible Subtractor Circuits

    Science.gov (United States)

    Haghparast, Majid; Monfared, Asma Taheri

    2018-01-01

    Reversible logic synthesis is an important area of current research because of its ability to reduce energy dissipation. In recent years, multiple valued logic has received great attention due to its ability to reduce the width of the reversible circuit which is a main requirement in quantum technology. Subtractor circuits are between major components used in quantum computers. In this paper, we will discuss the design of a quaternary quantum reversible half subtractor circuit using quaternary 1-qudit, 2-qudit Muthukrishnan-Stroud and 3-qudit controlled gates and a 2-qudit Generalized quaternary gate. Then a design of a quaternary quantum reversible full subtractor circuit based on the quaternary half subtractor will be presenting. The designs shall then be evaluated in terms of quantum cost, constant input, garbage output, and hardware complexity. The proposed quaternary quantum reversible circuits are the first attempt in the designing of the aforementioned subtractor.

  18. Parkinson’s disease managing reversible neurodegeneration

    Science.gov (United States)

    Hinz, Marty; Stein, Alvin; Cole, Ted; McDougall, Beth; Westaway, Mark

    2016-01-01

    Traditionally, the Parkinson’s disease (PD) symptom course has been classified as an irreversible progressive neurodegenerative disease. This paper documents 29 PD and treatment-induced systemic depletion etiologies which cause and/or exacerbate the seven novel primary relative nutritional deficiencies associated with PD. These reversible relative nutritional deficiencies (RNDs) may facilitate and accelerate irreversible progressive neurodegeneration, while other reversible RNDs may induce previously undocumented reversible pseudo-neurodegeneration that is hiding in plain sight since the symptoms are identical to the symptoms being experienced by the PD patient. Documented herein is a novel nutritional approach for reversible processes management which may slow or halt irreversible progressive neurodegenerative disease and correct reversible RNDs whose symptoms are identical to the patient’s PD symptoms. PMID:27103805

  19. Estimation and uncertainty of reversible Markov models.

    Science.gov (United States)

    Trendelkamp-Schroer, Benjamin; Wu, Hao; Paul, Fabian; Noé, Frank

    2015-11-07

    Reversibility is a key concept in Markov models and master-equation models of molecular kinetics. The analysis and interpretation of the transition matrix encoding the kinetic properties of the model rely heavily on the reversibility property. The estimation of a reversible transition matrix from simulation data is, therefore, crucial to the successful application of the previously developed theory. In this work, we discuss methods for the maximum likelihood estimation of transition matrices from finite simulation data and present a new algorithm for the estimation if reversibility with respect to a given stationary vector is desired. We also develop new methods for the Bayesian posterior inference of reversible transition matrices with and without given stationary vector taking into account the need for a suitable prior distribution preserving the meta-stable features of the observed process during posterior inference. All algorithms here are implemented in the PyEMMA software--http://pyemma.org--as of version 2.0.

  20. Drift reversal capability in helical systems

    International Nuclear Information System (INIS)

    Yokoyama, M.; Itoh, K.; Okamura, S.

    2002-10-01

    The maximum-J (J is the second adiabatic invariant) capability, i.e., the drift reversal capability, is examined in quasi-axisymmetric (QAS) stellarators and quasi-poloidally symmetric (QPS) stellarators as a possible mechanism for turbulent transport suppression. Due to the existence of non-axisymmetry of the magnetic field strength in QAS configurations, a local maximum of J is created to cause the drift reversal. The increase of magnetic shear in finite beta equilibria also has favorable effect in realizing the drift reversal. The radial variation of the uniform magnetic field component plays a crucial role for the drift reversal in a QPS configuration. Thus, the drift reversal capability and its external controllability are demonstrated for QAS and QPS stellarators, by which the impact of magnetic configuration on turbulent transport can be studied in experiments. (author)

  1. Drift reversal capability in helical systems

    International Nuclear Information System (INIS)

    Yokoyama, M.; Itoh, K.; Okamura, S.; Matsuoka, K.; Nakajima, N.; Itoh, S.-I.; Neilson, G.H.; Zarnstorff, M.C.; Rewoldt, G.

    2003-01-01

    The maximum-J (J is the second adiabatic invariant) capability, i.e., the drift reversal capability, is examined in quasi-axisymmetric (QAS) stellarators and quasi-poloidally symmetric (QPS) stellarators as a possible mechanism for turbulent transport suppression. Due to the existence of non-axisymmetry of the magnetic field strength in QAS configurations, a local maximum of J is created to cause the drift reversal. The increase of magnetic shear in finite beta equilibria also has favorable effect in realizing the drift reversal. The radial variation of the uniform magnetic field component plays a crucial role for the drift reversal in a QPS configuration. Thus, the drift reversal capability and its external controllability are demonstrated for QAS and QPS stellarators, by which the impact of magnetic configuration on turbulent transport can be studied in experiments. (author)

  2. Reversed field pinch ignition requirements

    International Nuclear Information System (INIS)

    Werley, K.A.

    1991-01-01

    Plasma models are described and used to calculated numerically the transport confinement (nτ E ) requirements and steady state operation points for both the reversed field pinch (RFP) and the tokamak. The models are used to examine the CIT tokamak ignition conditions and the RFP experimental and ignition conditions. Physics differences between RFPs and tokamaks and their consequences for a D-T ignition machine are discussed. Compared with a tokamak, the ignition RFP has many physics advantages, including Ohmic heating to ignition (no need for auxiliary heating systems), higher beta, lower ignition current, less sensitivity of ignition requirements to impurity effects, no hard disruptions (associated with beta or density limits) and successful operation with high radiation fractions (f RAD ∼ 0.95). These physics advantages, coupled with important engineering advantages associated with lower external magnetic field, larger aspect ratios and smaller plasma cross-sections, translate to significant cost reductions for both ignition and reactor applications. The primary drawback of the RFP is the uncertainty that the present scaling will extrapolate to reactor regimes. Devices that are under construction should go a long way toward resolving this scaling uncertainty. The 4 MA ZTH is expected to extend the nτ E transport scaling data by three orders of magnitude above the results of ZT-40M, and, if the present scaling holds, ZTH is expected to achieve a D-T equivalent scientific energy breakeven, Q = 1. A base case RFP ignition point is identified with a plasma current of 8.1 MA and no auxiliary heating. (author). 19 refs, 11 figs, 3 tabs

  3. Reversibility: An Engineer's Point of View

    Energy Technology Data Exchange (ETDEWEB)

    Berest, Pierre [LMS, ecole Polytechnique (France)

    2012-07-01

    Reversibility is the most consistent option in a democratic country. However reversibility may also have several drawbacks which must be identified and mitigated. Reversibility of a geological repository is a relatively new idea in France. The 1991 law dedicated to nuclear waste management considered reversibility as a possible option. Fifteen years later, the 2006 law mandated that a deep repository must be reversible and that the exact content of this notion should be defined by a new law to be discussed by the Parliament in 2015. Reversibility was not a concern put forward by engineers. It clearly originated from a societal demand sponsored and formulated by the Parliament. Since 1991, the exact meaning of this mandate progressively became more precise. In the early days, reversibility meant the technical and financial capability to retrieve the wastes from the repository, at least for some period of time after being emplaced. Progressively, a broader definition, suggested by Andra, was accepted: reversibility also means that a disposal facility should be operated in such a way that a stepwise decision-making process is possible. At each step, society must be able to decide to proceed to the next step, to pause or to reverse a step. Several benefits can be expected from a reversible repository. Some technical safety concerns may be only recognised after waste emplacement. Radioactive wastes may become a resource whose recoverability is desirable. Regulations may change, alternative waste treatment or better disposal techniques may be developed, or the need to modify a component of the facility may arise. Looking back at how chemical or domestic wastes were managed some 50 years ago easily underscores that it is not unreasonable to hope for significant advances in the future. For scientists and engineers, reversibility proves to have several other merits. To design and build a good repository, time is needed. The operator of a mine or of an oil field knows that

  4. Chemical reactions in reverse micelle systems

    Science.gov (United States)

    Matson, Dean W.; Fulton, John L.; Smith, Richard D.; Consani, Keith A.

    1993-08-24

    This invention is directed to conducting chemical reactions in reverse micelle or microemulsion systems comprising a substantially discontinuous phase including a polar fluid, typically an aqueous fluid, and a microemulsion promoter, typically a surfactant, for facilitating the formation of reverse micelles in the system. The system further includes a substantially continuous phase including a non-polar or low-polarity fluid material which is a gas under standard temperature and pressure and has a critical density, and which is generally a water-insoluble fluid in a near critical or supercritical state. Thus, the microemulsion system is maintained at a pressure and temperature such that the density of the non-polar or low-polarity fluid exceeds the critical density thereof. The method of carrying out chemical reactions generally comprises forming a first reverse micelle system including an aqueous fluid including reverse micelles in a water-insoluble fluid in the supercritical state. Then, a first reactant is introduced into the first reverse micelle system, and a chemical reaction is carried out with the first reactant to form a reaction product. In general, the first reactant can be incorporated into, and the product formed in, the reverse micelles. A second reactant can also be incorporated in the first reverse micelle system which is capable of reacting with the first reactant to form a product.

  5. Reversible Lithium Neurotoxicity: Review of the Literature

    Science.gov (United States)

    Netto, Ivan

    2012-01-01

    Objective: Lithium neurotoxicity may be reversible or irreversible. Reversible lithium neurotoxicity has been defined as cases of lithium neurotoxicity in which patients recovered without any permanent neurologic sequelae, even after 2 months of an episode of lithium toxicity. Cases of reversible lithium neurotoxicity differ in clinical presentation from those of irreversible lithium neurotoxicity and have important implications in clinical practice. This review aims to study the clinical presentation of cases of reversible lithium neurotoxicity. Data Sources: A comprehensive electronic search was conducted in the following databases: MEDLINE (PubMed), 1950 to November 2010; PsycINFO, 1967 to November 2010; and SCOPUS (EMBASE), 1950 to November 2010. MEDLINE and PsycINFO were searched by using the OvidSP interface. Study Selection: A combination of the following search terms was used: lithium AND adverse effects AND central nervous system OR neurologic manifestation. Publications cited include articles concerned with reversible lithium neurotoxicity. Data Extraction: The age, sex, clinical features, diagnostic categories, lithium doses, serum lithium levels, precipitating factors, and preventive measures of 52 cases of reversible lithium neurotoxicity were extracted. Data Synthesis: Among the 52 cases of reversible lithium neurotoxicity, patients ranged in age from 10 to 80 years and a greater number were female (P = .008). Most patients had affective disorders, schizoaffective disorders, and/or depression (P lithium levels were less than or equal to 1.5 mEq/L (P lithium, underlying brain pathology, abnormal tissue levels, specific diagnostic categories, and elderly populations were some of the precipitating factors reported for reversible lithium neurotoxicity. The preventive measures were also described. Conclusions: Reversible lithium neurotoxicity presents with a certain clinical profile and precipitating factors for which there are appropriate

  6. Reversible lithium neurotoxicity: review of the literatur.

    Science.gov (United States)

    Netto, Ivan; Phutane, Vivek H

    2012-01-01

    Lithium neurotoxicity may be reversible or irreversible. Reversible lithium neurotoxicity has been defined as cases of lithium neurotoxicity in which patients recovered without any permanent neurologic sequelae, even after 2 months of an episode of lithium toxicity. Cases of reversible lithium neurotoxicity differ in clinical presentation from those of irreversible lithium neurotoxicity and have important implications in clinical practice. This review aims to study the clinical presentation of cases of reversible lithium neurotoxicity. A comprehensive electronic search was conducted in the following databases: MEDLINE (PubMed), 1950 to November 2010; PsycINFO, 1967 to November 2010; and SCOPUS (EMBASE), 1950 to November 2010. MEDLINE and PsycINFO were searched by using the OvidSP interface. A combination of the following search terms was used: lithium AND adverse effects AND central nervous system OR neurologic manifestation. Publications cited include articles concerned with reversible lithium neurotoxicity. The age, sex, clinical features, diagnostic categories, lithium doses, serum lithium levels, precipitating factors, and preventive measures of 52 cases of reversible lithium neurotoxicity were extracted. Among the 52 cases of reversible lithium neurotoxicity, patients ranged in age from 10 to 80 years and a greater number were female (P = .008). Most patients had affective disorders, schizoaffective disorders, and/or depression (P lithium levels were less than or equal to 1.5 mEq/L (P lithium, underlying brain pathology, abnormal tissue levels, specific diagnostic categories, and elderly populations were some of the precipitating factors reported for reversible lithium neurotoxicity. The preventive measures were also described. Reversible lithium neurotoxicity presents with a certain clinical profile and precipitating factors for which there are appropriate preventive measures. This recognition will help in early diagnosis and prompt treatment of

  7. Parallelization of Reversible Ripple-carry Adders

    DEFF Research Database (Denmark)

    Thomsen, Michael Kirkedal; Axelsen, Holger Bock

    2009-01-01

    The design of fast arithmetic logic circuits is an important research topic for reversible and quantum computing. A special challenge in this setting is the computation of standard arithmetical functions without the generation of \\emph{garbage}. Here, we present a novel parallelization scheme...... wherein $m$ parallel $k$-bit reversible ripple-carry adders are combined to form a reversible $mk$-bit \\emph{ripple-block carry adder} with logic depth $\\mathcal{O}(m+k)$ for a \\emph{minimal} logic depth $\\mathcal{O}(\\sqrt{mk})$, thus improving on the $mk$-bit ripple-carry adder logic depth $\\mathcal...

  8. Reverse logistics in the Brazilian construction industry.

    Science.gov (United States)

    Nunes, K R A; Mahler, C F; Valle, R A

    2009-09-01

    In Brazil most Construction and Demolition Waste (C&D waste) is not recycled. This situation is expected to change significantly, since new federal regulations oblige municipalities to create and implement sustainable C&D waste management plans which assign an important role to recycling activities. The recycling organizational network and its flows and components are fundamental to C&D waste recycling feasibility. Organizational networks, flows and components involve reverse logistics. The aim of this work is to introduce the concepts of reverse logistics and reverse distribution channel networks and to study the Brazilian C&D waste case.

  9. Reversible perspective and splitting in time.

    Science.gov (United States)

    Hart, Helen Schoenhals

    2012-01-01

    The element of time--the experience of it and the defensive use of it--is explored in conjunction with the use of reversible perspective as a psychotic defense. Clinical material from a long analysis illustrates how a psychotic patient used the reversible perspective, with its static splitting, to abolish the experience of time. When he improved and the reversible perspective became less effective for him, he replaced it with a more dynamic splitting mechanism using time gaps. With further improvement, the patient began to experience the passage of time, and along with it the excruciating pain of separation, envy, and loss.

  10. Performance of the reverse Helmbold universal portfolio

    Science.gov (United States)

    Tan, Choon Peng; Kuang, Kee Seng; Lee, Yap Jia

    2017-04-01

    The universal portfolio is an important investment strategy in a stock market where no stochastic model is assumed for the stock prices. The zero-gradient set of the objective function estimating the next-day portfolio which contains the reverse Kullback-Leibler order-alpha divergence is considered. From the zero-gradient set, the explicit, reverse Helmbold universal portfolio is obtained. The performance of the explicit, reverse Helmbold universal portfolio is studied by running them on some stock-price data sets from the local stock exchange. It is possible to increase the wealth of the investor by using these portfolios in investment.

  11. Time reversibility in the quantum frame

    Energy Technology Data Exchange (ETDEWEB)

    Masot-Conde, Fátima [Escuela Superior Ingenieros, Dpt. Física Aplicada III, Universidad de Sevilla Isla Mágica, 41092- Sevilla (Spain)

    2014-12-04

    Classic Mechanics and Electromagnetism, conventionally taken as time-reversible, share the same concept of motion (either of mass or charge) as the basis of the time reversibility in their own fields. This paper focuses on the relationship between mobile geometry and motion reversibility. The goal is to extrapolate the conclusions to the quantum frame, where matter and radiation behave just as elementary mobiles. The possibility that the asymmetry of Time (Time’s arrow) is an effect of a fundamental quantum asymmetry of elementary particles, turns out to be a consequence of the discussion.

  12. Refractory reverse amblyopia with atropine penalization

    Directory of Open Access Journals (Sweden)

    Preeti Ajit Patil

    2010-01-01

    Full Text Available Pharmacological penalization with atropine has been shown to be equally effective as conventional occlusion therapy in the treatment of amblyopia in children. Reverse amblyopia of the sound eye with atropine penalization has been reported before, but is more common in cases where the effect is augmented with optical penalization and is mostly reversible. We report a case of reverse amblyopia with atropine penalization, in a 4-year-old girl, which was refractory to treatment. This report highlights the need for strict monitoring of the vision in the sound eye and regular follow-up in children undergoing amblyopia treatment.

  13. Reversible machine code and its abstract processor architecture

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Glück, Robert; Yokoyama, Tetsuo

    2007-01-01

    A reversible abstract machine architecture and its reversible machine code are presented and formalized. For machine code to be reversible, both the underlying control logic and each instruction must be reversible. A general class of machine instruction sets was proven to be reversible, building...

  14. Constraining the reversing and non-reversing modes of the geodynamo. New insights from magnetostratigraphy.

    Science.gov (United States)

    Gallet, Y.; Pavlov, V.; Shatsillo, A.; Hulot, G.

    2015-12-01

    Constraining the evolution in the geomagnetic reversal frequency over hundreds of million years is not a trivial matter. Beyond the fact that there are long periods without reversals, known as superchrons, and periods with many reversals, the way the reversal frequency changes through time during reversing periods is still debated. A smooth evolution or a succession of stationary segments have both been suggested to account for the geomagnetic polarity time scale since the Middle-Late Jurassic. Sudden changes from a reversing mode to a non-reversing mode of the geodynamo may also well have happened, the switch between the two modes having then possibly been controlled by the thermal conditions at the core-mantle boundary. There is, nevertheless, a growing set of magnetostratigraphic data, which could help decipher a proper interpretation of the reversal history, in particular in the early Paleozoic and even during the Precambrian. Although yielding a fragmentary record, these data reveal the occurrence of both additional superchrons and periods characterized by extremely high, not to say extraordinary, magnetic reversal frequencies. In this talk, we will present a synthesis of these data, mainly obtained from Siberia, and discuss their implication for the magnetic reversal behavior over the past billion years.

  15. Long-acting reversible hormonal contraception

    African Journals Online (AJOL)

    Abstract. Long-acting reversible hormonal contraceptives are effective methods of birth control that provide contraception for an extended ... The World Health Organization (WHO) has online tools available .... trials and marketing experience.

  16. Reversal of target-specific oral anticoagulants

    Science.gov (United States)

    Siegal, D.M.; Cuker, Adam

    2014-01-01

    Target-specific oral anticoagulants (TSOACs) provide safe and effective anticoagulation for the prevention and treatment of thrombosis in a variety of clinical settings by interfering with the activity of thrombin (dabigatran) or factor Xa (rivaroxaban, apixaban, edoxaban, betrixaban). Although TSOACs have practical advantages over vitamin K antagonists (VKAs), there are currently no antidotes to reverse their anticoagulant effect. Herein we summarize the available evidence for TSOAC reversal using nonspecific and specific reversal agents. We discuss important limitations of existing evidence, which is derived from studies in human volunteers, animal models and in vitro experiments. Studies evaluating the safety and efficacy of reversal agents on clinical outcomes such as bleeding and mortality in patients with TSOAC-associated bleeding are needed. PMID:24880102

  17. Magnetization reversal mechanisms under oblique magnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Ntallis, N.; Efthimiadis, K.G., E-mail: kge@auth.gr

    2017-03-01

    In this work finite element micromagnetic simulations were performed in order to study the reversal mechanisms of spherical ferromagnetic particles with uniaxial magnetocrystalline anisotropy, when they are magnetized along an oblique direction with respect to the anisotropy axis. Magnetization loops are taken in different directions of external magnetic field, at different anisotropy constants and particle sizes. In the simulation results, the three reversal mechanisms (coherent, curling and domains) are observed and new phenomena arise due to the action of oblique magnetic fields. Moreover, the dependence of the critical fields with respect to the angle of the external field is presented. - Highlights: • Finite element micromagnetic simulation of the three different reversal mechanisms. • For the curling mechanism, the new phenomenon is the rotation of the vortex. • In the domain reversal mechanism, the formed domain wall is smaller than 180°. • In soft ferromagnetic particles a rearrangement of the magnetic domains is observed.

  18. Medical abortion reversal: science and politics meet.

    Science.gov (United States)

    Bhatti, Khadijah Z; Nguyen, Antoinette T; Stuart, Gretchen S

    2018-03-01

    Medical abortion is a safe, effective, and acceptable option for patients seeking an early nonsurgical abortion. In 2014, medical abortion accounted for nearly one third (31%) of all abortions performed in the United States. State-level attempts to restrict reproductive and sexual health have recently included bills that require physicians to inform women that a medical abortion is reversible. In this commentary, we will review the history, current evidence-based regimen, and regulation of medical abortion. We will then examine current proposed and existing abortion reversal legislation. The objective of this commentary is to ensure physicians are armed with rigorous evidence to inform patients, communities, and policy makers about the safety of medical abortion. Furthermore, given the current paucity of evidence for medical abortion reversal, physicians and policy makers can dispel bad science and misinformation and advocate against medical abortion reversal legislation. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Stability of the field-reversed mirror

    International Nuclear Information System (INIS)

    Morse, E.C.

    1979-01-01

    The stability of a field reversed mirror plasma configuration is studied with an energy principle derived from the Vlasov equation. Because of finite orbit effects, the stability properties of a field-reversed mirror are different from the stability properties of similar magnetohydrodynamic equilibria. The Vlasov energy principle developed here is applied to a computer simulation of an axisymmetric field-reversed mirror state. It has been possible to prove that the l = 0 modes, called tearing modes, satisfy a sufficient condition for stability. Precessional modes, with l = 1, 2, are found to be unstable at low growth rate. This suggests possible turbulent behavior (Bohm confinement) in the experimental devices aiming at field reversal. Techniques for suppressing these instabilities are outlined, and the applicability of the Vlasov energy principle to more complicated equilibrium models is shown

  20. Modified and reverse radiometric flow injection analysis

    Energy Technology Data Exchange (ETDEWEB)

    Myint, U; Ba, H; Khin, M M; Aung, K; Thida, [Yangon Univ. (Myanmar). Dept. of Chemistry; Toelgyessy, J [Slovak Technical Univ., Bratislava (Slovakia). Dept. of Environmental Science

    1994-06-01

    Determination of [sup 137]Cs and [sup 60]Co by using modified and reverse radiometric flow injection analysis is described. Two component RFIA was also realized using [sup 60]Co and [sup 137]Cs radionuclides. (author) 2 refs.; 5 figs.

  1. Reverse-osmosis membranes by plasma polymerization

    Science.gov (United States)

    Hollahan, J. R.; Wydeven, T.

    1972-01-01

    Thin allyl amine polymer films were developed using plasma polymerization. Resulting dry composite membranes effectively reject sodium chloride during reverse osmosis. Films are 98% sodium chloride rejective, and 46% urea rejective.

  2. Reverse-symmetry waveguides: Theory and fabrication

    DEFF Research Database (Denmark)

    Horvath, R.; Lindvold, Lars René; Larsen, N.B.

    2002-01-01

    We present an extensive theoretical analysis of reverse-symmetry waveguides with special focus on their potential application as sensor components in aqueous media and demonstrate a novel method for fabrication of such waveguides. The principle of reverse symmetry is based on making the refractive...... index of the waveguide substrate less than the refractive index of the medium covering the waveguiding film (n(water) = 1.33). This is opposed to the conventional waveguide geometry, where the substrate is usually glass or polymers with refractive indices of approximate to1.5. The reverse configuration...... are combined with air-grooved polymer supports to form freestanding single-material polymer waveguides of reverse symmetry capable of guiding light....

  3. Time reversibility, computer simulation, algorithms, chaos

    CERN Document Server

    Hoover, William Graham

    2012-01-01

    A small army of physicists, chemists, mathematicians, and engineers has joined forces to attack a classic problem, the "reversibility paradox", with modern tools. This book describes their work from the perspective of computer simulation, emphasizing the author's approach to the problem of understanding the compatibility, and even inevitability, of the irreversible second law of thermodynamics with an underlying time-reversible mechanics. Computer simulation has made it possible to probe reversibility from a variety of directions and "chaos theory" or "nonlinear dynamics" has supplied a useful vocabulary and a set of concepts, which allow a fuller explanation of irreversibility than that available to Boltzmann or to Green, Kubo and Onsager. Clear illustration of concepts is emphasized throughout, and reinforced with a glossary of technical terms from the specialized fields which have been combined here to focus on a common theme. The book begins with a discussion, contrasting the idealized reversibility of ba...

  4. Optical reversible programmable Boolean logic unit.

    Science.gov (United States)

    Chattopadhyay, Tanay

    2012-07-20

    Computing with reversibility is the only way to avoid dissipation of energy associated with bit erase. So, a reversible microprocessor is required for future computing. In this paper, a design of a simple all-optical reversible programmable processor is proposed using a polarizing beam splitter, liquid crystal-phase spatial light modulators, a half-wave plate, and plane mirrors. This circuit can perform 16 logical operations according to three programming inputs. Also, inputs can be easily recovered from the outputs. It is named the "reversible programmable Boolean logic unit (RPBLU)." The logic unit is the basic building block of many complex computational operations. Hence the design is important in sense. Two orthogonally polarized lights are defined here as two logical states, respectively.

  5. Magnetostratigraphy of the Fossil-Rich Shungura Formation, southwest Ethiopia

    Science.gov (United States)

    Kidane, Tesfaye; Brown, Francis H.; Kidney, Casey

    2014-09-01

    Three hundred eighty-six oriented block samples were collected from the lower 334 m of Pliocene and Pleistocene fluvial strata of the Shungura Formation in two field seasons. Paleomagnetic polarity of these was determined on samples from these blocks, using a routine of 8-13 steps for AF demagnetization, and 15-20 steps for thermal demagnetization. Rock magnetic properties revealed titanomagnetite with subordinate maghemite as the dominant magnetic minerals with pseudo-single domain magnetic grain sizes. Directional analyses indicate one or two components of magnetization both in AF and thermal techniques. The first component is mostly removed by 5-10 mT AF fields or heating to 300 °C. The magnetization component after these steps generally defined straight-line segments directed towards the origin which are interpreted as the Characteristic Remanent Magnetization (ChRM). ChRM directions so determined and averaged at the site level revealed both normal and reversed polarities. The directions of the normal and reversed polarities are respectively Dec = 357°, Inc = -0.1 (N = 36, α95 = 3.7°) and Dec = 176°, Inc = -3.4 (N = 55, α95 = 3.1°) and are antipodal. A sequence of R4-N3-R3-N2-(R2)-N1-R1 polarities was identified with R2 being an anomalous direction within N2/N1. Published weighted mean 40Ar/39Ar ages on volcanic ash layers in this part of the section with height from the base and ages in parentheses are: Tuff A (34 m; 3.60 ± 0.02 Ma), Tuff B-α (65 m; 3.43 ± 0.01 Ma), Tuff B-δ (77 m; 3.41 ± 0.01 Ma), Tuff in B-10-1 (150 m; 2.97 ± 0.01 Ma), Tuff C (170 m; 2.99 ± 0.09 Ma), Tuff D (252 m; 2.53 ± 0.01 Ma), Tuff D-3-2 (272 m; 2.47 ± 0.01 Ma), and Tuff F (228 m; 2.32 ± 0.01 Ma). These direct age results imply that the identified polarity zones correspond to the Gilbert Chron, lower Gauss Chron, Mammoth Subchron, upper Gauss Chron, and lower Matuyama Chron, respectively. No new paleomagnetic data are available for the Usno Formation, but

  6. Elastic least-squares reverse time migration

    KAUST Repository

    Feng, Zongcai; Schuster, Gerard T.

    2016-01-01

    Elastic least-squares reverse time migration (LSRTM) is used to invert synthetic particle-velocity data and crosswell pressure field data. The migration images consist of both the P- and Svelocity perturbation images. Numerical tests on synthetic and field data illustrate the advantages of elastic LSRTM over elastic reverse time migration (RTM). In addition, elastic LSRTM images are better focused and have better reflector continuity than do the acoustic LSRTM images.

  7. SLE local martingales, reversibility and duality

    Energy Technology Data Exchange (ETDEWEB)

    Kytoelae, Kalle; Kemppainen, Antti [Department of Mathematics and Statistics, PO Box 68, FIN-00014 University of Helsinki (Finland)

    2006-11-17

    We study Schramm-Loewner evolutions (SLEs) reversibility and duality using the Virasoro structure of the space of local martingales. For both problems we formulate a setup where the questions boil down to comparing two processes at a stopping time. We state algebraic results showing that local martingales for the processes have enough in common. When one has in addition integrability, the method gives reversibility and duality for any polynomial expected value. (letter to the editor)

  8. SLE local martingales, reversibility and duality

    International Nuclear Information System (INIS)

    Kytoelae, Kalle; Kemppainen, Antti

    2006-01-01

    We study Schramm-Loewner evolutions (SLEs) reversibility and duality using the Virasoro structure of the space of local martingales. For both problems we formulate a setup where the questions boil down to comparing two processes at a stopping time. We state algebraic results showing that local martingales for the processes have enough in common. When one has in addition integrability, the method gives reversibility and duality for any polynomial expected value. (letter to the editor)

  9. Geomagnetic reversal in brunhes normal polarity epoch.

    Science.gov (United States)

    Smith, J D; Foster, J H

    1969-02-07

    The magnetic stratigraphly of seven cores of deep-sea sediment established the existence of a short interval of reversed polarity in the upper part of the Brunches epoch of normal polarity. The reversed zone in the cores correlates well with paleontological boundaries and is named the Blake event. Its boundaries are estimated to be 108,000 and 114,000 years ago +/- 10 percent.

  10. How the geomagnetic field vector reverses polarity

    Science.gov (United States)

    Prevot, M.; Mankinen, E.A.; Gromme, C.S.; Coe, R.S.

    1985-01-01

    A highly detailed record of both the direction and intensity of the Earth's magnetic field as it reverses has been obtained from a Miocene volcanic sequence. The transitional field is low in intensity and is typically non-axisymmetric. Geomagnetic impulses corresponding to astonishingly high rates of change of the field sometimes occur, suggesting that liquid velocity within the Earth's core increases during geomagnetic reversals. ?? 1985 Nature Publishing Group.

  11. Boosting reversible pushdown machines by preprocessing

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Kutrib, Martin; Malcher, Andreas

    2016-01-01

    languages, whereas for reversible pushdown automata the accepted family of languages lies strictly in between the reversible deterministic context-free languages and the real-time deterministic context-free languages. Moreover, it is shown that the computational power of both types of machines...... is not changed by allowing the preprocessing sequential transducer to work irreversibly. Finally, we examine the closure properties of the family of languages accepted by such machines....

  12. Elastic least-squares reverse time migration

    KAUST Repository

    Feng, Zongcai

    2016-09-06

    Elastic least-squares reverse time migration (LSRTM) is used to invert synthetic particle-velocity data and crosswell pressure field data. The migration images consist of both the P- and Svelocity perturbation images. Numerical tests on synthetic and field data illustrate the advantages of elastic LSRTM over elastic reverse time migration (RTM). In addition, elastic LSRTM images are better focused and have better reflector continuity than do the acoustic LSRTM images.

  13. Post-partum posterior reversible encephalopathy syndrome

    OpenAIRE

    B. V. Triveni; Salman Mohammed Sheikh; Deepak Shedde

    2014-01-01

    Posterior Reversible Encephalopathy Syndrome (PRES) is a clinicopathological syndrome associated with various clinical conditions presenting with headache, encephalopathy, seizure and cortical visual disturbances. Radiological findings in PRES are thought to be due to vasogenic edema predominantly in posterior cerebral hemispheres and are reversible with appropriate management. We present a case of post partum PRES,A 29 year old primigravida of 33 weeks 3 days period of gestation who prese...

  14. DIC-CAM recipe for reverse engineering

    Science.gov (United States)

    Romero-Carrillo, P.; Lopez-Alba, E.; Dorado, R.; Diaz-Garrido, F. A.

    2012-04-01

    Reverse engineering (RE) tries to model and manufacture an object from measurements one of a reference object. Modern optical measurement systems and computer aided engineering software have improved reverse engineering procedures. We detail the main RE steps from 3D digitalization by Digital Image Correlation to manufacturing. The previous description is complemented with an application example, which portrays the performance of RE. The differences between original and manufactured objects are less than 2 mm (close to the tool radius).

  15. Central structure preservation of the reversal sign

    International Nuclear Information System (INIS)

    Chen, C.J.

    1999-01-01

    We report serial changes of central structure preservation of the reversal sign in a case of child abuse. The serial CT images show that the relatively spared attenuation at the basal ganglia, thalami, and posterior fossa develops before the occurrence of transtentorial herniation. This finding makes the theory that central preservation of the reversal sign is due to pressure relief after transtentorial herniation less convincible. (orig.)

  16. Modified Borohydrides for Reversible Hydrogen Storage (2)

    International Nuclear Information System (INIS)

    Ming Au

    2006-01-01

    This paper reports the results in the effort to destabilize lithium borohydride for reversible hydrogen storage. A number of metals, metal hydrides, metal chlorides and complex hydrides were selected and evaluated as the destabilization agents for reducing de-hydriding temperature and generating de-hydriding-re-hydriding reversibility. It is found that some additives are effective. The Raman spectroscopic analysis shows the change of B-H binding nature. (authors)

  17. Central structure preservation of the reversal sign

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C.J. [Dept. of Diagnostic Radiology, Chang Gung Memorial Hospital, Taipei (Taiwan)

    1999-12-01

    We report serial changes of central structure preservation of the reversal sign in a case of child abuse. The serial CT images show that the relatively spared attenuation at the basal ganglia, thalami, and posterior fossa develops before the occurrence of transtentorial herniation. This finding makes the theory that central preservation of the reversal sign is due to pressure relief after transtentorial herniation less convincible. (orig.)

  18. Turbulent transport in reversed field pinches

    International Nuclear Information System (INIS)

    Christiansen, J.P.; Roberts, K.V.

    1976-01-01

    MHD stability of the Reversed Field Pinch (RFP) relies on reversal of the toroidal field component in the outer plasma region. Interest in this configuration comes from its potential economic advantages as a thermonuclear reactor, since compared to a Tokamak the RFP supports a higher value of β, the ratio between plasma and total magnetic pressure. Results of computations on the time-evolution of the RFP using a 1D MHD model are reported. (orig./GG) [de

  19. Rotating Reverse-Osmosis for Water Purification

    Science.gov (United States)

    Lueptow, RIchard M.

    2004-01-01

    A new design for a water-filtering device combines rotating filtration with reverse osmosis to create a rotating reverse- osmosis system. Rotating filtration has been used for separating plasma from whole blood, while reverse osmosis has been used in purification of water and in some chemical processes. Reverse- osmosis membranes are vulnerable to concentration polarization a type of fouling in which the chemicals meant not to pass through the reverse-osmosis membranes accumulate very near the surfaces of the membranes. The combination of rotating filtration and reverse osmosis is intended to prevent concentration polarization and thereby increase the desired flux of filtered water while decreasing the likelihood of passage of undesired chemical species through the filter. Devices based on this concept could be useful in a variety of commercial applications, including purification and desalination of drinking water, purification of pharmaceutical process water, treatment of household and industrial wastewater, and treatment of industrial process water. A rotating filter consists of a cylindrical porous microfilter rotating within a stationary concentric cylindrical outer shell (see figure). The aqueous suspension enters one end of the annulus between the inner and outer cylinders. Filtrate passes through the rotating cylindrical microfilter and is removed via a hollow shaft. The concentrated suspension is removed at the end of the annulus opposite the end where the suspension entered.

  20. Ascorbyl radical disproportionation in reverse micellar systems

    Science.gov (United States)

    Gębicki, J. L.; Szymańska-Owczarek, M.; Pacholczyk-Sienicka, B.; Jankowski, S.

    2018-04-01

    Ascorbyl radical was generated by the pulse radiolysis method and observed with the fast kinetic spectrophotometry within reverse micelles stabilized by AOT in n-heptane or by Igepal CO-520 in cyclohexane at different water to surfactant molar ratio, w0. Rate constants for the disproportionation of the ascorbyl radicals were smaller than those for intermicellar exchange for both type of reverse micelles and slower than those in homogeneous aqueous solutions. However, they increased with increasing w0 for AOT/n-heptane system, while they decreased for Igepal CO-520 system. The absorption spectra of ascorbic acid AOT/n-heptane reverse micellar system showed that the "pH" sensed by this molecule is lower than that in respective homogeneous aqueous solutions. The obtained results were rationalized taking into account three main factors (i) preferential location of ascorbic acid molecules in the interfacial region of the both types of reverse micelles; (ii) postulate that the pH of the interface is lower than that of the water pool of reverse micelles and (iii) different structure of the interface of the reverse micelles made by AOT in n-heptane and those formed by Igepal CO-520 I cyclohexane. Some possible consequences of these findings are discussed.

  1. Reversal modes in asymmetric Ni nanowires

    Energy Technology Data Exchange (ETDEWEB)

    Leighton, B.; Pereira, A. [Departamento de Fisica, Universidad de Santiago de Chile (USACH), Avda. Ecuador 3493, 917-0124 Santiago (Chile); Escrig, J., E-mail: jescrigm@gmail.com [Departamento de Fisica, Universidad de Santiago de Chile (USACH), Avda. Ecuador 3493, 917-0124 Santiago (Chile); Center for the Development of Nanoscience and Nanotechnology (CEDENNA), Avda. Ecuador 3493, 917-0124 Santiago (Chile)

    2012-11-15

    We have investigated the evolution of the magnetization reversal mechanism in asymmetric Ni nanowires as a function of their geometry. Circular nanowires are found to reverse their magnetization by the propagation of a vortex domain wall, while in very asymmetric nanowires the reversal is driven by the propagation of a transverse domain wall. The effect of shape asymmetry of the wire on coercivity and remanence is also studied. Angular dependence of the remanence and coercivity is also addressed. Tailoring the magnetization reversal mechanism in asymmetric nanowires can be useful for magnetic logic and race-track memory, both of which are based on the displacement of magnetic domain walls. Finally, an alternative method to detect the presence of magnetic drops is proposed. - Highlights: Black-Right-Pointing-Pointer Asymmetry strongly modifies the magnetic behavior of a wire. Black-Right-Pointing-Pointer Very asymmetric nanowires reverse their magnetization by a transverse domain wall. Black-Right-Pointing-Pointer An alternative method to detect the presence of magnetic drops is proposed. Black-Right-Pointing-Pointer Tailoring the reversal mode in asymmetric nanowires can be useful for potential applications.

  2. Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression

    Directory of Open Access Journals (Sweden)

    Ru-Yin Tsai

    2016-06-01

    Conclusion: Resveratrol restores the antinociceptive effect of morphine by reversing morphine infusion-induced spinal cord neuroinflammation and increase in TNFR1 expression. The reversal of the morphine-induced increase in TNFR1 expression by resveratrol is partially due to reversal of the morphine infusion-induced increase in HDAC1 expression. Resveratrol pretreatment can be used as an adjuvant in clinical pain management for patients who need long-term morphine treatment or with neuropathic pain.

  3. The misconception of mean-reversion

    International Nuclear Information System (INIS)

    Eliazar, Iddo I; Cohen, Morrel H

    2012-01-01

    The notion of random motion in a potential well is elemental in the physical sciences and beyond. Quantitatively, this notion is described by reverting diffusions—asymptotically stationary diffusion processes which are simultaneously (i) driven toward a reversion level by a deterministic force, and (ii) perturbed off the reversion level by a random white noise. The archetypal example of reverting diffusions is the Ornstein–Uhlenbeck process, which is mean-reverting. In this paper we analyze reverting diffusions and establish that: (i) if the magnitude of the perturbing noise is constant then the diffusion's stationary density is unimodal and the diffusion is mode-reverting; (ii) if the magnitude of the perturbing noise is non-constant then, in general, neither is the diffusion's stationary density unimodal, nor is the diffusion mode-reverting. In the latter case we further establish a result asserting when unimodality and mode-reversion do hold. In particular, we demonstrate that the notion of mean-reversion, which is fundamental in economics and finance, is a misconception—as mean-reversion is an exception rather than the norm. (fast track communication)

  4. Reverse logistics in the construction industry.

    Science.gov (United States)

    Hosseini, M Reza; Rameezdeen, Raufdeen; Chileshe, Nicholas; Lehmann, Steffen

    2015-06-01

    Reverse logistics in construction refers to the movement of products and materials from salvaged buildings to a new construction site. While there is a plethora of studies looking at various aspects of the reverse logistics chain, there is no systematic review of literature on this important subject as applied to the construction industry. Therefore, the objective of this study is to integrate the fragmented body of knowledge on reverse logistics in construction, with the aim of promoting the concept among industry stakeholders and the wider construction community. Through a qualitative meta-analysis, the study synthesises the findings of previous studies and presents some actions needed by industry stakeholders to promote this concept within the real-life context. First, the trend of research and terminology related with reverse logistics is introduced. Second, it unearths the main advantages and barriers of reverse logistics in construction while providing some suggestions to harness the advantages and mitigate these barriers. Finally, it provides a future research direction based on the review. © The Author(s) 2015.

  5. Parkinson’s disease managing reversible neurodegeneration

    Directory of Open Access Journals (Sweden)

    Hinz M

    2016-04-01

    Full Text Available Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Beth McDougall,4 Mark Westaway5 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, 2Stein Orthopedic Associates, Plantation, FL, 3Cole Center for Healing, Cincinnati, OH, 4CLEARCenter of Health, Mill Valley, CA, USA; 5Four Pillars Health, Brendale, QLD, Australia Abstract: Traditionally, the Parkinson’s disease (PD symptom course has been classified as an irreversible progressive neurodegenerative disease. This paper documents 29 PD and treatment-induced systemic depletion etiologies which cause and/or exacerbate the seven novel primary relative nutritional deficiencies associated with PD. These reversible relative nutritional deficiencies (RNDs may facilitate and accelerate irreversible progressive neurodegeneration, while other reversible RNDs may induce previously undocumented reversible pseudo-neurodegeneration that is hiding in plain sight since the symptoms are identical to the symptoms being experienced by the PD patient. Documented herein is a novel nutritional approach for reversible processes management which may slow or halt irreversible progressive neurodegenerative disease and correct reversible RNDs whose symptoms are identical to the patient’s PD symptoms. Keywords: Parkinson’s disease, L-dopa, carbidopa, B6, neurodegeneration

  6. AN OVERVIEW ON RETAIL REVERSE LOGISTICS

    Directory of Open Access Journals (Sweden)

    Ioana Olariu

    2014-07-01

    Full Text Available This article is a theoretical approach on retail reverse logistics. Environmental concern and the current marketing strategy have spurred retailers to implement strategies to facilitate product returns from end customers. Reverse logistics, indicating the process of this return flow, encompasses such activities as the movement of returned products, facilities to accommodate returned items, and overall remedy process for returned items. The retail industry, under great competitive pressure, has used return policies as a competitive weapon. Grocery retailers were the first to begin to focus serious attention on the problem of returns and to develop reverse logistics innovations. Grocery retailers first developed innovations such as reclamation centers. Reclamation centers, in turn, led to the establishment of centralized return centers. Centralizing returns has led to significant benefits for most firms that have implemented them. Over the last several years, retailers have consolidated. Now, more than ever, reverse logistics is seen as being important. This reverse distribution activity can be crucial to the survival of companies, because the permanent goodwill of the company is at stake. Businesses succeed because they respond to both external and internal changes and adjust in an effective manner to remain competitive.

  7. Toward a possible next geomagnetic transition?

    OpenAIRE

    A. De Santis; E. Qamili; L. Wu

    2013-01-01

    The geomagnetic field is subject to possible reversals or excursions of polarity during its temporal evolution. Considering that: (a) the typical average time between one reversal and the next (the so-called chron) is around 300 000 yr, (b) the last reversal occurred around 780 000 yr ago, (c) more excursions (rapid changes of polarity) can occur within the same chron and (d) the geomagnetic field dipole is currently decreasing, a possible imminent geomagne...

  8. Pattern-reversal electroretinograms in unilateral glaucoma.

    Science.gov (United States)

    Wanger, P; Persson, H E

    1983-06-01

    Pattern-reversal and flash electroretinograms (ERG) and oscillatory potentials (OP) were recorded from 11 patients with unilateral glaucoma. All glaucomatous eyes had reduced amplitudes both compared to the opposite eye in the same patient and to reference values. In 10 of the 11 cases this reduction was below the level of normal variation. The difference in pattern-reversal ERG amplitude means from glaucomatous and opposite eyes was statistically significant. No differences were observed in flash ERGs or OPs. The histopathologic correlate to the visual field defects in glaucoma is retinal ganglion cell degeneration. The present electrophysiologic findings support the view, based on results from animal experiments, that the pattern-reversal ERG reflects ganglion cell activity.

  9. Medulla Oblongata Hemorrhage and Reverse Takotsubo Cardiomyopathy.

    Science.gov (United States)

    Gobeske, Kevin T; Sarano, Maurice E; Fugate, Jennifer E; Wijdicks, Eelco F

    2017-12-19

    Acute brain injury with strong surges of adrenergic outflow has resulted in takotsubo cardiomyopathy, but there are surprisingly few reports of takotsubo cardiomyopathy after intracranial hemorrhage, and none have been described from hemorrhage within the brainstem. We describe a patient with reverse and reversible cardiomyopathy following a hemorrhage in the lateral medulla oblongata. While it is limited in size, the location of the hemorrhage caused acute systolic failure with left ventricular ejection fraction of 27% and vasopressor requirement for cardiogenic shock and pulmonary edema. There was full recovery after 7 days. Detailed case report. Hemorrhage into medulla oblongata pressor centers may result in acute, reversible, stress-induced cardiomyopathy, affirming the adrenergic origin of this condition.

  10. Neutrophil Reverse Migration Becomes Transparent with Zebrafish

    Directory of Open Access Journals (Sweden)

    Taylor W. Starnes

    2012-01-01

    Full Text Available The precise control of neutrophil-mediated inflammation is critical for both host defense and the prevention of immunopathology. In vivo imaging studies in zebrafish, and more recently in mice, have made the novel observation that neutrophils leave a site of inflammation through a process called neutrophil reverse migration. The application of advanced imaging techniques to the genetically tractable, optically transparent zebrafish larvae was critical for these advances. Still, the mechanisms underlying neutrophil reverse migration and its effects on the resolution or priming of immune responses remain unclear. Here, we review the current knowledge of neutrophil reverse migration, its potential roles in host immunity, and the live imaging tools that make zebrafish a valuable model for increasing our knowledge of neutrophil behavior in vivo.

  11. Time in Science: Reversibility vs. Irreversibility

    Science.gov (United States)

    Pomeau, Yves

    To discuss properly the question of irreversibility one needs to make a careful distinction between reversibility of the equations of motion and the choice of the initial conditions. This is also relevant for the rather confuse philosophy of the wave packet reduction in quantum mechanics. The explanation of this reduction requires also to make precise assumptions on what initial data are accessible in our world. Finally I discuss how a given (and long) time record can be shown in an objective way to record an irreversible or reversible process. Or: can a direction of time be derived from its analysis? This leads quite naturally to examine if there is a possible spontaneous breaking of the time reversal symmetry in many body systems, a symmetry breaking that would be put in evidence objectively by looking at certain specific time correlations.

  12. Fuel bundle movement due to reverse flow

    Energy Technology Data Exchange (ETDEWEB)

    Wahba, N N; Akalin, O [Ontario Hydro, Toronto, ON (Canada)

    1996-12-31

    When a break occurs in the inlet feeder or inlet header, the rapid depressurization will cause the channel flow to reverse forcing the string of bundles to accelerate and impact with upstream shield plug. A model has been developed to predict the bundle motion due to the channel flow reversal. The model accounts for various forces acting on the bundle. A series of five reverse flow, bundle acceleration experiments have been conducted simulating a break in the inlet feeder of a CANDU fuel channel. The model has been validated against the experiments. The predicted impact velocities are in good agreement with the measured values. It is demonstrated that the model may be successfully used in predicting bundle relocation timing following a large LOCA (loss of coolant). (author). 7 refs., 3 tabs., 11 figs.

  13. Reversible Carnot cycle outside a black hole

    International Nuclear Information System (INIS)

    Xi-Hao, Deng; Si-Jie, Gao

    2009-01-01

    A Carnot cycle outside a Schwarzschild black hole is investigated in detail. We propose a reversible Carnot cycle with a black hole being the cold reservoir. In our model, a Carnot engine operates between a hot reservoir with temperature T 1 and a black hole with Hawking temperature T H . By naturally extending the ordinary Carnot cycle to the black hole system, we show that the thermal efficiency for a reversible process can reach the maximal efficiency 1 – T H /T 1 . Consequently, black holes can be used to determine the thermodynamic temperature by means of the Carnot cycle. The role of the atmosphere around the black hole is discussed. We show that the thermal atmosphere provides a necessary mechanism to make the process reversible. (general)

  14. REVERSIBLE VENTILATION SYSTEM FOR ADMINISTRATIVE BUILDINGS

    Directory of Open Access Journals (Sweden)

    Valery Yu. Kravchuk

    2017-01-01

    Full Text Available Abstract. Objectives To consider the possibility of applying the principle of reversing air flows for a centralised ventilation system; to develop a specific scheme for air exchange reversible ventilation, which will take into account the peculiarities of the microclimate of administrative buildings; to select the type of filling of the air-permeable element and justify this choice; to determine the conditions for changing the direction of air movement in the ventilation system and the area of its application; to form a list of equipment necessary for the operation of such a system; to consider the influence of supply and exhaust devices on the heat and humidity regime of claddings. Methods  To achieve this goal, the published thematic material was reviewed and a patent search carried out using Russian and European databases. Data on mathematical modelling of filtration in porous media and experimental results were used. A method for ventilating rooms in administrative building using the reversal of movement of supply and exhaust air streams along the same channels was applied. Results  Schemas for reversible ventilation systems are presented and their modes of operation considered. It is established that the idea of reversing ventilation flows has not yet been applied in the development of centralised ventilation systems. Based on these published materials, it was concluded that the proposed design of supply and exhaust devices can be used in practice. An original air exchange scheme for the ventilation of administrative buildings and design of supply and exhaust devices for this system are proposed. The conditions for changing the operating modes of the system and the scope of its application are determined. Conclusion The use of the proposed ventilation system allows normative air exchange to be provided without using a supply unit during the cold season. This application of airflow reversal allows the potential of natural forces to be used

  15. Post-partum posterior reversible encephalopathy syndrome

    DEFF Research Database (Denmark)

    Aaen, Anne Albers; Jeppesen, Jørgen; Obaid, Hayder

    2015-01-01

    Posterior reversible encephalopathy syndrome (PRES) is a complex clinical condition with vasogenic subcortical oedema caused by hypertension. Oedema is often seen on magnetic resonance imaging. The wide clinical spectrum ranges from headaches to vision loss and even death. Early diagnosis...... and treatment is important for the reversibility of the condition. In this case report we emphasize the importance of blood pressure control in a post-partum woman, who had a rather complicated pregnancy. The symptoms of PRES were not recognized immediately because of failure to use and acknowledge a blood...

  16. Research regarding reverse engineering for aircraft components

    Directory of Open Access Journals (Sweden)

    Udroiu Razvan

    2017-01-01

    Full Text Available Reverse engineering is a useful technique used in manufacturing and design process of new components. In aerospace industry new components can be developed, based on existing components without technical Computer Aided Design (CAD data, in order to reduce the development cycle of new products. This paper proposes a methodology wherein the CAD model of turbine blade can be build using computer aided reverse engineering technique utilising a 5 axis Coordinate Measuring Machine (CMM. The proposed methodology uses a scanning strategy by features, followed by a design methodology for 3D modelling of complex shapes.

  17. A simple statistical model for geomagnetic reversals

    Science.gov (United States)

    Constable, Catherine

    1990-01-01

    The diversity of paleomagnetic records of geomagnetic reversals now available indicate that the field configuration during transitions cannot be adequately described by simple zonal or standing field models. A new model described here is based on statistical properties inferred from the present field and is capable of simulating field transitions like those observed. Some insight is obtained into what one can hope to learn from paleomagnetic records. In particular, it is crucial that the effects of smoothing in the remanence acquisition process be separated from true geomagnetic field behavior. This might enable us to determine the time constants associated with the dominant field configuration during a reversal.

  18. Reverse preferential spread in complex networks

    Science.gov (United States)

    Toyoizumi, Hiroshi; Tani, Seiichi; Miyoshi, Naoto; Okamoto, Yoshio

    2012-08-01

    Large-degree nodes may have a larger influence on the network, but they can be bottlenecks for spreading information since spreading attempts tend to concentrate on these nodes and become redundant. We discuss that the reverse preferential spread (distributing information inversely proportional to the degree of the receiving node) has an advantage over other spread mechanisms. In large uncorrelated networks, we show that the mean number of nodes that receive information under the reverse preferential spread is an upper bound among any other weight-based spread mechanisms, and this upper bound is indeed a logistic growth independent of the degree distribution.

  19. Post-partum posterior reversible encephalopathy syndrome

    DEFF Research Database (Denmark)

    Aaen, Anne Albers; Jeppesen, Jørgen; Obaid, Hayder

    2015-01-01

    and treatment is important for the reversibility of the condition. In this case report we emphasize the importance of blood pressure control in a post-partum woman, who had a rather complicated pregnancy. The symptoms of PRES were not recognized immediately because of failure to use and acknowledge a blood......Posterior reversible encephalopathy syndrome (PRES) is a complex clinical condition with vasogenic subcortical oedema caused by hypertension. Oedema is often seen on magnetic resonance imaging. The wide clinical spectrum ranges from headaches to vision loss and even death. Early diagnosis...

  20. [Post-partum posterior reversible encephalopathy syndrome].

    Science.gov (United States)

    Aaen, Anne Albers; Jeppesen, Jørgen; Obaid, Hayder; Bülow, Hans Henrik

    2015-11-23

    Posterior reversible encephalopathy syndrome (PRES) is a complex clinical condition with vasogenic subcortical oedema caused by hypertension. Oedema is often seen on magnetic resonance imaging. The wide clinical spectrum ranges from headaches to vision loss and even death. Early diagnosis and treatment is important for the reversibility of the condition. In this case report we emphasize the importance of blood pressure control in a post-partum woman, who had a rather complicated pregnancy. The symptoms of PRES were not recognized immediately because of failure to use and acknowledge a blood pressure test.

  1. Reversed Extension Flow of Polymer melts

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.; Nielsen, Jens Kromann

    2007-01-01

    The measurement of the startup of uni axial elongational flow (potentially until steady state) followed by reversed bi axial flow, both with a constant elongational rate was made possible using a Filament Stretching Rheometer (FSR). The filament stretching rheometer rheometer is surrounded...... by a thermostated environment and allows measurements on polymeric melts and liquids from room temperatures until 200 °C. In the experiments the Hencky strain at which the stress becomes zero (the recovery strain) of the reversed flow can be identified....

  2. Reversible computing fundamentals, quantum computing, and applications

    CERN Document Server

    De Vos, Alexis

    2010-01-01

    Written by one of the few top internationally recognized experts in the field, this book concentrates on those topics that will remain fundamental, such as low power computing, reversible programming languages, and applications in thermodynamics. It describes reversible computing from various points of view: Boolean algebra, group theory, logic circuits, low-power electronics, communication, software, quantum computing. It is this multidisciplinary approach that makes it unique.Backed by numerous examples, this is useful for all levels of the scientific and academic community, from undergr

  3. Contextual influences on reverse knowledge transfer

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2010-01-01

    Further development of theories about how contextual factors influence the beneficial reverse knowledge transfer from subsidiary to head quarters in disparate national country contexts, is the aim of our study. Earlier studies do not fully capture the different effects national country cultures can....... A proposition model is developed where the dependent variable is beneficial reverse knowledge transfer. The independent variables are: higher relative knowledge level in subsidiaty than in HQ, authority respect, activity fit with contextual learning preference. The conclusion suggest that different contexts...

  4. Microscopic reversibility and the information contained in the composition vector

    CERN Document Server

    Luetich, J J

    2001-01-01

    The microscopic level of observation is the level where every (hypothetical) transformation is reversible. As during reversible processes no composition information is generated by the system, when transforming composition variables, microscopic reversibility is the other side of the coin. This paper is the fourth member of a tetralogy conceived to give insight into the concept of microscopic reversibility.

  5. Design of a novel quantum reversible ternary up-counter

    Science.gov (United States)

    Houshmand, Pouran; Haghparast, Majid

    2015-08-01

    Reversible logic has been recently considered as an interesting and important issue in designing combinational and sequential circuits. The combination of reversible logic and multi-valued logic can improve power dissipation, time and space utilization rate of designed circuits. Only few works have been reported about sequential reversible circuits and almost there are no paper exhibited about quantum ternary reversible counter. In this paper, first we designed 2-qutrit and 3-qutrit quantum reversible ternary up-counters using quantum ternary reversible T-flip-flop and quantum reversible ternary gates. Then we proposed generalized quantum reversible ternary n-qutrit up-counter. We also introduced a new approach for designing any type of n-qutrit ternary and reversible counter. According to the results, we can conclude that applying second approach quantum reversible ternary up-counter is better than the others.

  6. END-OF-USE PRODUCTS IN REVERSE LOGISTICS

    OpenAIRE

    Marta Starostka-Patyk

    2007-01-01

    Reverse logistics is a very useful tool for enterprises which have to deal with end-of-use products. Forward logistics is not able to manage them, because they show up on the beginning of reverse supply chain. That is the reason for growing importance of reverse flows. Reverse logistics is quite new logistics system. This paper presents the idea of reverse logistics and end-of-use products problems.

  7. Magnetostratigraphy of the Ahuachapan-Chipilapa geothermal field, El Salvador

    Energy Technology Data Exchange (ETDEWEB)

    Fucugauchi, Jaime Urrutia [Universidad Nacional Autonoma de Mexico, Lab. de Paleomagnetismo y Geofisica Nuclear, Coyoacan (Mexico); Rodriguez, Vicente Torres; Partida, Eduardo Gonzalez [Instituto de Investigaciones Electricas, Dept. de Geotermia, Cuernavaca, Morelos (Mexico)

    1997-12-01

    The volcanic stratigraphy for the Ahuachapan-Chipilapa geothermal field is defined on the basis of the magnetostratigraphic results on 156 oriented samples from 33 sites. The magnetostratigraphic sequence shows that the major volcanism associated with the Concepcion de Ataco caldera and the Cuyanausul volcano took place during the middle Brunhes chron (Quaternary). Pre-caldera activity of small centers such as Empalizada and Apaneca in the southern sector of the field occurred during the early Brunhes (0.77{+-}0.07 Ma). Basaltic-andesitic activity associated with the Cuyanausul volcano took place earlier, i.e. during the Matuyama chron, possibly around 1.3{+-}0.15 and 1.7{+-}0.3 Ma. The local igneous basement is composed of Late Miocene-Pliocene andesites, ignimbrites and volcano-sedimentary deposits. Normal polarities and a K-Ar date of 7.37{+-}0.73 Ma indicate that the volcanic activity in the study area extends beyond the Gauss chron. The polarity of some of the units in the post-caldera sequence and in the Concepcion de Ataco and Cuyanausul sequences suggest that they may have recorded short polarity sub-chrons. (Author)

  8. Energy drift in reversible time integration

    International Nuclear Information System (INIS)

    McLachlan, R I; Perlmutter, M

    2004-01-01

    Energy drift is commonly observed in reversible integrations of systems of molecular dynamics. We show that this drift can be modelled as a diffusion and that the typical energy error after time T is O(√T). (letter to the editor)

  9. Predicting flux decline of reverse osmosis membranes

    NARCIS (Netherlands)

    Schippers, J.C.; Hanemaayer, J.H.; Smolders, C.A.; Kostense, A.

    1981-01-01

    A mathematical model predicting flux decline of reverse osmosis membranes due to colloidal fouling has been verified. This mathema- tical model is based on the theory of cake or gel filtration and the Modified Fouling Index (MFI). Research was conducted using artificial colloidal solutions and a

  10. Multiples least-squares reverse time migration

    KAUST Repository

    Zhang, Dongliang; Zhan, Ge; Dai, Wei; Schuster, Gerard T.

    2013-01-01

    To enhance the image quality, we propose multiples least-squares reverse time migration (MLSRTM) that transforms each hydrophone into a virtual point source with a time history equal to that of the recorded data. Since each recorded trace is treated

  11. "At Sea": Reversibility in Teaching and Learning

    Science.gov (United States)

    Cavicchi, Elizabeth Mary

    2018-01-01

    An equal-armed balance at equilibrium--the bar is horizontal--tips into disequilibrium upon displacing a weight. Equilibrium is restored by reversing that move--putting the weight back where it was, or doing the same on the other side. Piaget adopted the idea of equilibration to describe how the intellect, in relating to the world, develops.…

  12. Reverse Logistics: RFID the key to optimality

    Directory of Open Access Journals (Sweden)

    Rezwan Asif

    2011-07-01

    Full Text Available Purpose: The purpose of this paper is to find ways to reduce uncertainties in Reverse logistic supply chain (RLSC through the use of Radio-frequency identification (RFID technology.Design/methodology/approach: This paper reviews literature and builds model to relate RFID with uncertainties in order to optimize Reverse Logistics. Findings: RFID is really efficient to determine and detect quantity, variety and cycle times of returns; however it's not as convenient to determine quality of the returns. The collected information from RFID can be used to standardize the RLSC.Research limitations: Though it’s several and unique advantages some limitations of RFID have been identified in quality and processing sequence, collecting points and different standards, and in global usage.Originality/value: Previous studies in the area of Reverse Logistics and RFID don’t cover all impacts of this technology on RLSC. This review paper has investigated these impacts and offers a model for optimizing the Reverse Logistics Supply Chain.

  13. Kinetin Reversal of NaCl Effects

    Science.gov (United States)

    Katz, Adriana; Dehan, Klara; Itai, Chanan

    1978-01-01

    Leaf discs of Nicotiana rustica L. were floated on NaCl in the presence of kinetin or abscisic acid. On the 5th day 14CO2 fixation, [3H]leucine incorporation, stomatal conductance, and chlorophyll content were determined. Kinetin either partially or completely reversed the inhibitory effects of NaCl while ABA had no effect. PMID:16660618

  14. Sustainable reverse logistics for household plastic waste

    NARCIS (Netherlands)

    Bing, X.

    2014-01-01

    Summary of the thesis titled “Sustainable Reverse Logistics for Household Plastic Waste”

    PhD Candidate: Xiaoyun Bing

    Recycled plastic can be used in the manufacturing of plastic products to reduce the use of virgin plastics material. The cost of recycled plastics is usually lower

  15. Reverse ray tracing for transformation optics.

    Science.gov (United States)

    Hu, Chia-Yu; Lin, Chun-Hung

    2015-06-29

    Ray tracing is an important technique for predicting optical system performance. In the field of transformation optics, the Hamiltonian equations of motion for ray tracing are well known. The numerical solutions to the Hamiltonian equations of motion are affected by the complexities of the inhomogeneous and anisotropic indices of the optical device. Based on our knowledge, no previous work has been conducted on ray tracing for transformation optics with extreme inhomogeneity and anisotropicity. In this study, we present the use of 3D reverse ray tracing in transformation optics. The reverse ray tracing is derived from Fermat's principle based on a sweeping method instead of finding the full solution to ordinary differential equations. The sweeping method is employed to obtain the eikonal function. The wave vectors are then obtained from the gradient of that eikonal function map in the transformed space to acquire the illuminance. Because only the rays in the points of interest have to be traced, the reverse ray tracing provides an efficient approach to investigate the illuminance of a system. This approach is useful in any form of transformation optics where the material property tensor is a symmetric positive definite matrix. The performance and analysis of three transformation optics with inhomogeneous and anisotropic indices are explored. The ray trajectories and illuminances in these demonstration cases are successfully solved by the proposed reverse ray tracing method.

  16. Detecting A Botnet By Reverse Engineering

    Directory of Open Access Journals (Sweden)

    Oesman Hendra Kelana

    2013-06-01

    Full Text Available Abstract— Botnet malware is a malicious program. Botnet that infects computers, called bots, will be controlled by a botmaster to do various things such as: spamming, phishing, keylogging Distributed Denial of Service (DDoS and other activities that are generally profitable to the owner of the bot (botmaster or those who use botnet services. The problem is that many computers have been controlled by botnets without the knowledge of the computer owner.  There are many ways to examine botnets, for example by studying the traffic from the botnet network, studying how botnets communicate to each, studying how each robot receives orders to do something, and so forth. Of the many methods, the most frequently and commonly used is the reverse engineering, where researchers study how a botnet works by botnet debugging. In this study the author tries to understand or research botnets by taking a type of botnet, namely Agobot, using reverse engineering.  One of the result of the research is that malware program files in general and in particular botnet has a technique to obscure the way that research using reverse engineering. Another result also shows that the botnet Agobot runs on computers by using the Windows service, and by changing the Windows registry so that every time the computer starts, Agobot always actively works in the computer memory. Keywords— Malware, Bot, Botnet, Botmaster, Agobot, Spam, Distributed Denial of Services, Identity Theft, Computer Security, Reverse Engineering, Debug, Windows Service, the Registry.

  17. Purchasing Power Parity and Heterogeneous Mean Reversion

    NARCIS (Netherlands)

    C.G. Koedijk (Kees); B. Tims (Ben); M.A. van Dijk (Mathijs)

    2005-01-01

    textabstractThis paper analyzes the properties of multivariate tests of purchasing power parity (PPP) that fail to take heterogeneity in the speed of mean reversion across real exchange rates into account. We compare the performance of homogeneous and heterogeneous unit root testing methodologies.

  18. Survey of methods for rapid spin reversal

    International Nuclear Information System (INIS)

    McKibben, J.L.

    1980-01-01

    The need for rapid spin reversal technique in polarization experiments is discussed. The ground-state atomic-beam source equipped with two rf transitions for hydrogen can be reversed rapidly, and is now in use on several accelerators. It is the optimum choice provided the accelerator can accept H + ions. At present all rapid reversal experiments using H - ions are done with Lamb-shift sources; however, this is not a unique choice. Three methods for the reversal of the spin of the atomic beam within the Lamb-shift source are discussed in order of development. Coherent intensity and perhaps focus modulation seem to be the biggest problems in both types of sources. Methods for reducing these modulations in the Lamb-shift source are discussed. The same Lamb-shift apparatus is easily modified to provide information on the atomic physics of quenching of the 2S/sub 1/2/ states versus spin orientation, and this is also discussed. 2 figures

  19. Reverse Logistics in Food Supply Chains

    NARCIS (Netherlands)

    Zeimpekis, V.; Bloemhof, J.M.; Bourlakis, M.

    2014-01-01

    Reverse logistics can be defined as the process of planning, implementing, and controlling the flow of raw materials, in-process inventory, and finished goods from the point of consumption to the point of origin for the purpose of recapturing value or proper disposal. In environmental and economic

  20. Bayesian analysis for reversible Markov chains

    NARCIS (Netherlands)

    Diaconis, P.; Rolles, S.W.W.

    2006-01-01

    We introduce a natural conjugate prior for the transition matrix of a reversible Markov chain. This allows estimation and testing. The prior arises from random walk with reinforcement in the same way the Dirichlet prior arises from Pólya’s urn. We give closed form normalizing constants, a simple

  1. Reversibility of continuous-variable quantum cloning

    International Nuclear Information System (INIS)

    Filip, Radim; Marek, Petr; Fiurasek, Jaromir

    2004-01-01

    We analyze a reversibility of optimal Gaussian 1→2 quantum cloning of a coherent state using only local operations on the clones and classical communication between them and propose a feasible experimental test of this feature. Performing Bell-type homodyne measurement on one clone and anticlone, an arbitrary unknown input state (not only a coherent state) can be restored in the other clone by applying appropriate local unitary displacement operation. We generalize this concept to a partial reversal of the cloning using only local operations and classical communication (LOCC) and we show that this procedure converts the symmetric cloner to an asymmetric cloner. Further, we discuss a distributed LOCC reversal in optimal 1→M Gaussian cloning of coherent states which transforms it to optimal 1→M ' cloning for M ' < M. Assuming the quantum cloning as a possible eavesdropping attack on quantum communication link, the reversibility can be utilized to improve the security of the link even after the attack

  2. Reverse electrodialysis : evaluation of suitable electrode systems

    NARCIS (Netherlands)

    Veerman, J.; Saakes, M.; Metz, S. J.; Harmsen, G. J.

    Reverse electrodialysis (RED) is a method for directly extracting electrical energy from salinity gradients, especially from sea and river water. For the commercial implementation of RED, the electrode system is a key component. In this paper, novel electrode systems for RED were compared with

  3. Female genital mutilation reversal: a general approach.

    Science.gov (United States)

    Anand, Mallika; Stanhope, Todd J; Occhino, John A

    2014-07-01

    Female genital mutilation (FGM) is a violation of human rights; yet, more than 100 million females are estimated to have undergone the procedure worldwide. There is an increased need for physician education in treating FGM. Female pelvic surgeons have a unique opportunity to treat this population of patients. Here, we depict the classification of FGM and a general approach to FGM reversal. We specifically address the procedure of type III FGM reversal, or defibulation. In this video, we first highlight the importance of the problem of FGM. Next, we present the classification of FGM using an original, simple, schematic diagram highlighting they key anatomic structures involved in the four types of FGM. We then present a simple case of reversal of type III FGM, a procedure also known as defibulation. After depicting the surgical procedure, we discuss clinical results and summarize key principles of the defibulation procedure. Our patient was a 25-year-old woman who had undergone type III FGM as a child in Somalia. She desired restoration of vaginal function. We performed a reversal, and her postoperative course was uncomplicated. By 6 weeks postoperatively, she was able to engage in sexual intercourse without dyspareunia. FGM is a problem at the doorsteps of female pelvic medicine and reconstructive surgery. Our video demonstrates a basic surgical approach that can be applied to simple cases of type III FGM presenting to the female pelvic surgeon.

  4. Adiabatic process reversibility: microscopic and macroscopic views

    International Nuclear Information System (INIS)

    Anacleto, Joaquim; Pereira, Mario G

    2009-01-01

    The reversibility of adiabatic processes was recently addressed by two publications. In the first (Miranda 2008 Eur. J. Phys. 29 937-43), an equation was derived relating the initial and final volumes and temperatures for adiabatic expansions of an ideal gas, using a microscopic approach. In that relation the parameter r accounts for the process reversibility, ranging between 0 and 1, which corresponds to the free and reversible expansion, respectively. In the second (Anacleto and Pereira 2009 Eur. J. Phys. 30 177-83), the authors have shown that thermodynamics can effectively and efficiently be used to obtain the general law for adiabatic processes carried out by an ideal gas, including compressions, for which r≥1. The present work integrates and extends the aforementioned studies, providing thus further insights into the analysis of the adiabatic process. It is shown that Miranda's work is wholly valid for compressions. In addition, it is demonstrated that the adiabatic reversibility coefficient given in terms of the piston velocity and the root mean square velocity of the gas particles is equivalent to the macroscopic description, given just by the quotient between surroundings and system pressure values. (letters and comments)

  5. Garbageless reversible implementation of integer linear transformations

    DEFF Research Database (Denmark)

    Burignat, Stéphane; Vermeirsch, Kenneth; De Vos, Alexis

    2013-01-01

    inputs. The resulting reversible circuit is able to perform both the forward transform and the inverse transform. Which of the two computations that actually is performed, simply depends on the orientation of the circuit when it is inserted in a computer board (if one takes care to provide...

  6. Flow reversal power limit for the HFBR

    International Nuclear Information System (INIS)

    Cheng, L.Y.; Tichler, P.R.

    1997-01-01

    The High Flux Beam Reactor (HFBR) is a pressurized heavy water moderated and cooled research reactor that began operation at 40 MW. The reactor was subsequently upgraded to 60 MW and operated at that level for several years. The reactor undergoes a buoyancy-driven reversal of flow in the reactor core following certain postulated accidents. Questions which were raised about the afterheat removal capability during the flow reversal transition led to a reactor shutdown and subsequent resumption of operation at a reduced power of 30 MW. An experimental and analytical program to address these questions is described in this report. The experiments were single channel flow reversal tests under a range of conditions. The analytical phase involved simulations of the tests to benchmark the physical models and development of a criterion for dryout. The criterion is then used in simulations of reactor accidents to determine a safe operating power level. It is concluded that the limit on the HFBR operating power with respect to the issue of flow reversal is in excess of 60 MW. Direct use of the experimental results and an understanding of the governing phenomenology supports this conclusion

  7. Reversible thermal gelation in soft spheres

    DEFF Research Database (Denmark)

    Kapnistos, M.; Vlassopoulos, D.; Fytas, G.

    2000-01-01

    Upon heating, concentrated solutions of star polymers and block copolymer micelles in a good solvent, representing soft spheres, undergo a reversible gelation. This phenomenon is attributed to the formation of clusters causing a partial dynamic arrest of the swollen interpenetrating spheres at hi...

  8. Returnable containers: an example of reverse logistics

    NARCIS (Netherlands)

    L.G. Kroon (Leo); G.M.C. Vrijens

    1996-01-01

    textabstractConsiders the application of returnable containers as an example of reverse logistics. A returnable container is a type of secondary packaging that can be used several times in the same form, in contrast with traditional cardboard boxes. For this equipment to be used, a system for the

  9. Remendable Polymeric Materials Using Reversible Covalent Bonds

    Science.gov (United States)

    2008-12-01

    response in poly(ethylene-co-methacrylic acid ) copolymers. Journal of The Royal Society Interface, 4, 405-411. Kavitha, A. A., and N. K. Singha...2007: A tailor-made polymethacrylate bearing a reactive diene in reversible diels-alder reaction. J. Polym. Sci. A Polym. Chem., 45, 4441-4449

  10. Strong and Reversible Monovalent Supramolecular Protein Immobilization

    NARCIS (Netherlands)

    Young, Jacqui F.; Nguyen, Hoang D.; Yang, Lanti; Huskens, Jurriaan; Jonkheijm, Pascal; Brunsveld, Luc

    2010-01-01

    Proteins with an iron clasp: Site-selective incorporation of a ferrocene molecule into a protein allows for easy, strong, and reversible supramolecular protein immobilization through a selective monovalent interaction of the ferrocene with a cucurbit[7]uril immobilized on a gold surface. The

  11. Long acting reversible contraception | Kluge | Obstetrics and ...

    African Journals Online (AJOL)

    Long acting reversible contraception (LARC) has great potential in reducing these pregnancies as they are highly effective and do not rely a great deal on compliance and correct use. They have better continuation rates than short term hormonal contraception and as per definition require administration less than once per ...

  12. Time reversal technique for gas leakage detection.

    Science.gov (United States)

    Maksimov, A O; Polovinka, Yu A

    2015-04-01

    The acoustic remote sensing of subsea gas leakage traditionally uses sonars as active acoustic sensors and hydrophones picking up the sound generated by a leak as passive sensors. When gas leaks occur underwater, bubbles are produced and emit sound at frequencies intimately related to their sizes. The experimental implementation of an acoustic time-reversal mirror (TRM) is now well established in underwater acoustics. In the basic TRM experiment, a probe source emits a pulse that is received on an array of sensors, time reversed, and re-emitted. After time reversal, the resulting field focuses back at the probe position. In this study, a method for enhancing operation of the passive receiving system has been proposed by using it in the regime of TRM. Two factors, the local character of the acoustic emission signal caused by the leakage and a resonant nature of the bubble radiation at their birth, make particularly effective scattering with the conjugate wave (CW). Analytical calculations are performed for the scattering of CW wave on a single bubble when CW is formed by bubble birthing wail received on an array, time reversed, and re-emitted. The quality of leakage detection depends on the spatio-temporal distribution of ambient noise.

  13. Posterior reversible encephalopathy syndrome in patient

    African Journals Online (AJOL)

    abp

    2015-05-26

    May 26, 2015 ... reversible Posterior leukoencephalopathy syndrome [1, 2]. The. PRES is a clinical and radiological entity associating varying degrees, headaches, impaired consciousness, seizures and visual disturbances to neurological and radiological abnormalities of the parietal-occipital white matter [3]. PRES has a ...

  14. Compound nucleus studies withy reverse kinematics

    International Nuclear Information System (INIS)

    Moretto, L.G.

    1985-06-01

    Reverse kinematics reactions are used to demonstrate the compound nucleus origin of intermediate mass particles at low energies and the extension of the same mechanism at higher energies. No evidence has appeared in our energy range for liquid-vapor equilibrium or cold fragmentation mechanisms. 11 refs., 12 figs

  15. Muscular activation during reverse and non-reverse chewing cycles in unilateral posterior crossbite.

    Science.gov (United States)

    Piancino, Maria Grazia; Farina, Dario; Talpone, Francesca; Merlo, Andrea; Bracco, Pietro

    2009-04-01

    The aim of this study was to characterize the kinematics and masseter muscle activation in unilateral posterior crossbite. Eighty-two children (8.6 +/- 1.3 yr of age) with unilateral posterior crossbite and 12 children (8.9 +/- 0.6 yr of age) with normal occlusion were selected for the study. Electromyography (EMG) and kinematics were concurrently recorded during mastication of a soft bolus and a hard bolus. The percentage of reverse cycles in the group of patients was 59.0 +/- 33.1% (soft bolus) and 69.7 +/- 29.7% (hard bolus) when chewing on the crossbite side. When chewing on the non-affected side, the number of reverse cycles was 16.7 +/- 24.5% (soft bolus) and 16.7 +/- 22.3% (hard bolus). The reverse cycles on the crossbite side were narrower with respect to the cycles on the non-affected side. Although both types of cycles in patients resulted in lower EMG activity of the masseter of the crossbite side than of the contralateral masseter, the activity of the non-affected side was larger for reverse than for non-reverse cycles. It was concluded that when chewing on the crossbite side, the masseter activity is reduced on the mastication side (crossbite) and is unaltered (non-reverse cycles) or increased (reverse) on the non-affected side.

  16. Dynamical similarity of geomagnetic field reversals.

    Science.gov (United States)

    Valet, Jean-Pierre; Fournier, Alexandre; Courtillot, Vincent; Herrero-Bervera, Emilio

    2012-10-04

    No consensus has been reached so far on the properties of the geomagnetic field during reversals or on the main features that might reveal its dynamics. A main characteristic of the reversing field is a large decrease in the axial dipole and the dominant role of non-dipole components. Other features strongly depend on whether they are derived from sedimentary or volcanic records. Only thermal remanent magnetization of lava flows can capture faithful records of a rapidly varying non-dipole field, but, because of episodic volcanic activity, sequences of overlying flows yield incomplete records. Here we show that the ten most detailed volcanic records of reversals can be matched in a very satisfactory way, under the assumption of a common duration, revealing common dynamical characteristics. We infer that the reversal process has remained unchanged, with the same time constants and durations, at least since 180 million years ago. We propose that the reversing field is characterized by three successive phases: a precursory event, a 180° polarity switch and a rebound. The first and third phases reflect the emergence of the non-dipole field with large-amplitude secular variation. They are rarely both recorded at the same site owing to the rapidly changing field geometry and last for less than 2,500 years. The actual transit between the two polarities does not last longer than 1,000 years and might therefore result from mechanisms other than those governing normal secular variation. Such changes are too brief to be accurately recorded by most sediments.

  17. Reversible Posterior Leukoencephalopathy Syndrome Induced by Pazopanib

    Directory of Open Access Journals (Sweden)

    Chelis Leonidas

    2012-10-01

    Full Text Available Abstract Background The reversible posterior leukoencephalopathy syndrome is a clinical/radiological syndrome characterized by headache, seizures, impaired vision, acute hypertension, and typical magnetic resonance imaging findings. There are several reports in the literature that depict its occurrence in cancer patients. The list of common anticancer and supportive care drugs that predispose to reversible posterior leukoencephalopathy syndrome is expanding and includes not only a large number of chemotherapeutic agents but also an increased number of new targeted drugs, particularly angiogenesis inhibitors such as bevacizumab,sorefenib and sunitinib. Pazopanib is an oral tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor, platelet-derived growth factor receptor, and c-Kit which after a positive phase III randomized clinical trial in patients with advanced renal cell cancer received FDA approval for the treatment of advanced renal cell carcinoma. Until now no cases of reversible posterior leukoencephalopathy syndrome induced by pazopanib have been reported. Case report We present the case of a 40 years old female patient with heavily pre-treated metastatic renal cell carcinoma who received pazopanib as salvage treatment. After 21 days of pazopanib therapy the patient referred to the emergency department with epileptic seizure, impaired vision at both eyes and headache. MRI of the brain revealed subcortical oedema at the occipital and parietal lobes bilaterally. She was treated with anticonvulsants, i.v. administration of mannitol and antihypertensives and she recovered completely from her symptoms and was discharged on the tenth hospital day. A brain MRI performed 3 weeks after showed that the subcortical oedema had been subsided. Conclusion In conclusion this is the first case of pazopanib induced reversible posterior leukoencephalopathy syndrome. Although usually reversible, this syndrome is a serious and

  18. Reversible Posterior Leukoencephalopathy Syndrome Induced by Pazopanib

    International Nuclear Information System (INIS)

    Chelis, Leonidas; Kakolyris, Stylianos; Souftas, Vasilios; Amarantidis, Kiriakos; Xenidis, Nikolaos; Chamalidou, Eleni; Dimopoulos, Prokopios; Michailidis, Prodromos; Christakidis, Evagelos; Prassopoulos, Panagiotis

    2012-01-01

    The reversible posterior leukoencephalopathy syndrome is a clinical/radiological syndrome characterized by headache, seizures, impaired vision, acute hypertension, and typical magnetic resonance imaging findings. There are several reports in the literature that depict its occurrence in cancer patients. The list of common anticancer and supportive care drugs that predispose to reversible posterior leukoencephalopathy syndrome is expanding and includes not only a large number of chemotherapeutic agents but also an increased number of new targeted drugs, particularly angiogenesis inhibitors such as bevacizumab,sorefenib and sunitinib. Pazopanib is an oral tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor, platelet-derived growth factor receptor, and c-Kit which after a positive phase III randomized clinical trial in patients with advanced renal cell cancer received FDA approval for the treatment of advanced renal cell carcinoma. Until now no cases of reversible posterior leukoencephalopathy syndrome induced by pazopanib have been reported. We present the case of a 40 years old female patient with heavily pre-treated metastatic renal cell carcinoma who received pazopanib as salvage treatment. After 21 days of pazopanib therapy the patient referred to the emergency department with epileptic seizure, impaired vision at both eyes and headache. MRI of the brain revealed subcortical oedema at the occipital and parietal lobes bilaterally. She was treated with anticonvulsants, i.v. administration of mannitol and antihypertensives and she recovered completely from her symptoms and was discharged on the tenth hospital day. A brain MRI performed 3 weeks after showed that the subcortical oedema had been subsided. In conclusion this is the first case of pazopanib induced reversible posterior leukoencephalopathy syndrome. Although usually reversible, this syndrome is a serious and potentially life threatening adverse effect, if untreated, that should

  19. Flux trapping during field reversal in a field reversed theta pinch

    International Nuclear Information System (INIS)

    Milroy, R.D.; Hoffman, A.L.; Slough, J.T.; Harding, D.G.

    1983-01-01

    In this paper we present new results from both numerical and experimental studies of the formation of the conducting sheath near the tube wall and its effectiveness in trapping bias flux during field reversal

  20. A Reverse Shock in GRB 160509A

    Science.gov (United States)

    Laskar, Tanmoy; Alexander, Kate D.; Berger, Edo; Fong, Wen-fai; Margutti, Raffaella; Shivvers, Isaac; Williams, Peter K. G.; Kopač, Drejc; Kobayashi, Shiho; Mundell, Carole; Gomboc, Andreja; Zheng, WeiKang; Menten, Karl M.; Graham, Melissa L.; Filippenko, Alexei V.

    2016-12-01

    We present the second multi-frequency radio detection of a reverse shock in a γ-ray burst. By combining our extensive radio observations of the Fermi-Large Area Telescope γ-ray burst 160509A at z = 1.17 up to 20 days after the burst with Swift X-ray observations and ground-based optical and near-infrared data, we show that the afterglow emission comprises distinct reverse shock and forward shock contributions: the reverse shock emission dominates in the radio band at ≲10 days, while the forward shock emission dominates in the X-ray, optical, and near-infrared bands. Through multi-wavelength modeling, we determine a circumburst density of {n}0≈ {10}-3 {{cm}}-3, supporting our previous suggestion that a low-density circumburst environment is conducive to the production of long-lasting reverse shock radiation in the radio band. We infer the presence of a large excess X-ray absorption column, N H ≈ 1.5 × 1022 {{cm}}-2, and a high rest-frame optical extinction, A V ≈ 3.4 mag. We identify a jet break in the X-ray light curve at {t}{jet}≈ 6 {days}, and thus derive a jet opening angle of {θ }{jet}≈ 4^\\circ , yielding a beaming-corrected kinetic energy and radiated γ-ray energy of {E}{{K}}≈ 4× {10}50 erg and {E}γ ≈ 1.3× {10}51 erg (1-104 keV, rest frame), respectively. Consistency arguments connecting the forward shocks and reverse shocks suggest a deceleration time of {t}{dec} ≈ 460 s ≈ T 90, a Lorentz factor of {{Γ }}({t}{dec})≈ 330, and a reverse-shock-to-forward-shock fractional magnetic energy density ratio of {R}{{B}}\\equiv {ɛ }{{B},{RS}}/{ɛ }{{B},{FS}}≈ 8. Our study highlights the power of rapid-response radio observations in the study of the properties and dynamics of γ-ray burst ejecta.

  1. ‘Picking People to Hate’: Reversible reversals in stand-up comedy

    DEFF Research Database (Denmark)

    Keisalo, Marianna Päivikki

    2017-01-01

    Generally speaking, ritual reversals mean switching to the opposite of what is considered ‘the normal order’. Such reversals can occur, for example, in terms of social hierarchies in rites of passage, in action in carnival, or in the framing of action as ritual or performance. For comedic figures...... cultural grounds and show how the study of comedic performance can offer insights into the semiotics of performance more broadly....

  2. Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin☆

    OpenAIRE

    Roche, Camille J.; Dantsker, David; Heller, Elizabeth R.; Sabat, Joseph E.; Friedman, Joel M.

    2013-01-01

    Hydration waters impact protein dynamics. Dissecting the interplay between hydration waters and dynamics requires a protein that manifests a broad range of dynamics. Proteins in reverse micelles (RMs) have promise as tools to achieve this objective because the water content can be manipulated. Hemoglobin is an appropriate tool with which to probe hydration effects. We describe both a protocol for hemoglobin encapsulation in reverse micelles and a facile method using PEG and cosolvents to mani...

  3. Reverse logistics policy – differences between conservative and innovative reverse logistics management

    Directory of Open Access Journals (Sweden)

    Alena Klapalová

    2013-01-01

    Full Text Available One of the of the key barriers that hampers effective and efficient management of reverse flows detected within a number of empirical surveys and case studies focused on reverse logistics and/or return management is business (organisational policy, specifically lack of policy, deficiency in existing policy or inferior policy. Despite this fact, there is a gap in literature which would show some evidence from practice that innovative reverse logistics policy both can pay off and is associated with certain aspects of reverse logistics management. Such proof can have several implications. It can support the call for better understanding and more research of the linkages of reverse logistics with other corporate functions, promote the acceptation of strategic character of reverse logistics and stress the role of RL policy within the rest of overall corporate management.The aim of this paper is to contribute and to enrich the existing body of knowledge concerning the above-mentioned gap through presentation of survey results that was realized in 2012 among managers of 244 Czech firms. The results demonstrate the statistically significant association between the innovativeness of RL policy and profitability of firms, quality of RL planning, perception of RL importance, level of RL knowledge and perception of product innovation importance for firms’ competitiveness and frequency of product innovation. They also reveal statistically significant differences between firms with conservative and innovative RL policy and the perceived existence of some barriers to manage RL.

  4. Dissaving of the Past via Reverse Mortgages

    Directory of Open Access Journals (Sweden)

    Ana Luiza Champloni

    Full Text Available We build a simple two-period general equilibrium model with incomplete markets which incorporates reverse market mortgages without appealing to the complicated framework required by the infinite horizon models. Two types of agents are considered: elderly agents and investors. The former are owners of physical assets (for instance housing who will want to sell them to investors. For that end the elderly agents, who are assumed to not have any bequest motive, issue claims against physical assets they own. One of the claims issued will be interpreted as reverse mortgage (loan for seniors and the other one as a call option written on the value of housing equity. By assuming that both the elderly agents and the investors are price takers, and by applying the generalized game approach, we show that the equilibrium in this economy always exists, providing the usual conditions on utilities and initial endowments are satisfied. We end with a remark on efficiency of the quilibrium.

  5. Posterior reversible encephalopathy syndrome: A case report

    Directory of Open Access Journals (Sweden)

    Kostić Dejan

    2015-01-01

    Full Text Available Posterior reversible encephalopathy syndrome (PRES is characterized by the following symptoms: seizures, impaired consciousness and/or vision, vomiting, nausea, and focal neurological signs. Diagnostic imaging includes examination by magnetic resonance (MR and computed tomography (CT, where brain edema is visualized bi-laterally and symmetrically, predominantly posteriorly, parietally, and occipitally. Case report. We presented a 73-year-old patient with the years-long medical history of hipertension and renal insufficiency, who developed PRES with the symptomatology of the rear cranium. CT and MR verified changes in the white matter involving all lobes on both sides of the brain. After a two-week treatment (antihypertensive, hypolipemic and rehydration therapy clinical improvement with no complications occurred, with complete resolution of changes in the white matter observed on CT and MR. Conclusion. PRES is a reversible syndrome in which the symptoms withdraw after several days to several weeks if early diagnosis is made and appropriate treatment started without delay.

  6. Time-Reversal Generation of Rogue Waves

    Science.gov (United States)

    Chabchoub, Amin; Fink, Mathias

    2014-03-01

    The formation of extreme localizations in nonlinear dispersive media can be explained and described within the framework of nonlinear evolution equations, such as the nonlinear Schrödinger equation (NLS). Within the class of exact NLS breather solutions on a finite background, which describe the modulational instability of monochromatic wave trains, the hierarchy of rational solutions localized in both time and space is considered to provide appropriate prototypes to model rogue wave dynamics. Here, we use the time-reversal invariance of the NLS to propose and experimentally demonstrate a new approach to constructing strongly nonlinear localized waves focused in both time and space. The potential applications of this time-reversal approach include remote sensing and motivated analogous experimental analysis in other nonlinear dispersive media, such as optics, Bose-Einstein condensates, and plasma, where the wave motion dynamics is governed by the NLS.

  7. Heavy metal removal using reverse osmosis

    Directory of Open Access Journals (Sweden)

    Lucia Gajdošová

    2009-12-01

    Full Text Available The aim of this work was to study reverse osmosis characteristics for copper, nickel and zinc removal from technological aqueoussolutions. Reverse osmosis (RO is a separation process that uses pressure to force a solution through a membrane that retainsthe solute on one side and allows the pure solvent to pass to the other side. A polyamide thin-film composite membrane TW30-1812-50was used. The difference in flux decline is significant. There is a significant difference in flux decline depending on the anions of usedheavy metal salts. The heavy metal concentration also has a significant influence on the membrane separation. There is alsoa significant difference in flux decline depending on the transmembrane pressure.

  8. Time reversal tests in polarized neutron reactions

    International Nuclear Information System (INIS)

    Asahi, Koichiro; Bowman, J.D.; Crawford, B.

    1998-01-01

    This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). In recent years the nuclear weak interaction has been studied in the compound nucleus via parity violation. The observed parity-violating effects are strongly enhanced by nuclear structure. The predictions are that the interaction of polarized neutrons with polarized nuclear targets could be also used to perform sensitive tests of time-reversal-violation because of the nuclear enhancements. The author has designed experiments to search for time-reversal violation in neutron-nucleus interactions. He has also developed techniques to polarize neutrons with laser-polarized 3 He gas targets. Using the polarized 3 He neutron spin filter, he has performed two experiments at LANSCE: an absolute neutron beam polarization measurement with an accuracy of 0.2--0.3% and a neutron spin-rotation measurement on a 139 La sample

  9. Microscopic theory of ultrafast spin linear reversal

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, G P, E-mail: gpzhang@indstate.edu [Department of Physics, Indiana State University, Terre Haute, IN 47809 (United States)

    2011-05-25

    A recent experiment (Vahaplar et al 2009 Phys. Rev. Lett. 103 117201) showed that a single femtosecond laser can reverse the spin direction without spin precession, or spin linear reversal (SLR), but its microscopic theory has been missing. Here we show that SLR does not occur naturally. Two generic spin models, the Heisenberg and Hubbard models, are employed to describe magnetic insulators and metals, respectively. We find analytically that the spin change is always accompanied by a simultaneous excitation of at least two spin components. The only model that has prospects for SLR is the Stoner single-electron band model. However, under the influence of the laser field, the orbital angular momenta are excited and are coupled to each other. If a circularly polarized light is used, then all three components of the orbital angular momenta are excited, and so are their spins. The generic spin commutation relation further reveals that if SLR exists, it must involve a complicated multiple state excitation.

  10. Reverse osmosis membrane allows in situ regeneration

    International Nuclear Information System (INIS)

    Bonhomme, N.; Menjeaud, C.; Poyet, C.

    1989-01-01

    The use of mineral membranes on metallic supports has provided a novel solution to the problem of filtration by the reverse osmosis process. A new reverse osmosis membrane is described which is capable of resisting high operational temperatures (120 0 C), fluctuations in pH(3 to 12) and high pressure (100 bar), as well as significant chlorine concentrations. In addition, the membrane can be regenerated in-situ on the same porous metal support. Numerous membranes can thus be used over the multi-year life of the porous support. Moreover, accidental damage to the membrane is of no great consequence as the membrane itself can be easily replaced. The life of the installation can thus be extended and the overall cost of filtration reduced. The membrane's various applications include water and effluent treatment in the nuclear power industry. (author)

  11. Cranial MR finding of reversible eclampsia

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Seok Ho; Hwang, Mi Young; Kim, Kyu Hwa; Kim, Seon Goo; Lee, Sung Moon; Kim, Hong; Joo, Yang Goo; Suh, Soo Ji [College of Medicine, Keimyung University, Daegu (Korea, Republic of)

    1994-05-15

    To evaluate clinical usefulness of cranial magnetic resonance imaging(MRI) in diagnosis and for follow-up of reversible eclampsia. Cranial MRI was performed on four consecutive pregnant patients(ante-partum 3 cases, postpartum 1 cases), who had generalized tonic-clonic seizure caused by eclampsia. One of the four patients underwent follow-up MRI. Cranial MRI typically demonstrated bilateral hyperintense lesions on T2-weighted images and iso-to hypointense lesions on T1-weighted images. MRI abnormalities were most commonly located in the distribution of the posterior cerebral artery circulation and were associated with symptoms of visual disturbance. Most cranial lesions of eclampsia demonstrated in MRI were reversible. MRI with its capability to detect even subtle abnormalities in the brain that are not visible on CT, and may be the technique of choice for evaluating the cerebral the pathology of pregnant women with eclampsia.

  12. Crystallization features of ternary reversible reciprocal systems

    International Nuclear Information System (INIS)

    Tomashik, V.N.; Shcherbak, L.P.; Fejchuk, P.I.; Grytsiv, V.I.

    2006-01-01

    Some features of the primary crystallization of phases in ternary reversible reciprocal system are considered and discussed. The diagonal join CdTe-GeSe of the CdTe + GeSe = CdSe + GeTe ternary reciprocal system is studied to show that the features in primary and secondary heating and cooling curves in such systems under fully equilibrium conditions are not reproduced upon consecutive heating and cooling sessions, because of the existence of different amounts of the reagents and the reaction products in the mixture; the temperatures of each transformation lie in a range. Those who experimentally investigate other ternary and more complex reversible reciprocal systems should take this fact into account [ru

  13. Quantum vertex model for reversible classical computing.

    Science.gov (United States)

    Chamon, C; Mucciolo, E R; Ruckenstein, A E; Yang, Z-C

    2017-05-12

    Mappings of classical computation onto statistical mechanics models have led to remarkable successes in addressing some complex computational problems. However, such mappings display thermodynamic phase transitions that may prevent reaching solution even for easy problems known to be solvable in polynomial time. Here we map universal reversible classical computations onto a planar vertex model that exhibits no bulk classical thermodynamic phase transition, independent of the computational circuit. Within our approach the solution of the computation is encoded in the ground state of the vertex model and its complexity is reflected in the dynamics of the relaxation of the system to its ground state. We use thermal annealing with and without 'learning' to explore typical computational problems. We also construct a mapping of the vertex model into the Chimera architecture of the D-Wave machine, initiating an approach to reversible classical computation based on state-of-the-art implementations of quantum annealing.

  14. Antiproton Production beam and Reverse Injection System

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, G.

    1981-08-16

    The objectives of this project are two fold: (1) To extract high energy protons from the Main Ring (MR) and target them to produce antiprotons which are subsequently captured in the existing Booster accelerator; and (2) to provide a channel for injecting either protons or antiprotons into the MR from the booster in a direction opposite to that of the normal proton acceleration as colliding beams can be created. The present design, therefore, is in support of two separate larger projects, viz., the collisions of protons in the Tevatron (normal circulation direction) with 'reverse injected' protons in the MR, and the collision of normal direction protons with reverse injected antiprotons either in the MR or in the Tevatron. Figure 1 shows the layout of the project area. It spans the shortest distance between possible injection/ejection points in the existing accelerator structures, hence minimizing costs. The tunnel will lie underground at the level of the MR and booster.

  15. Laser heating of field-reversed configurations

    International Nuclear Information System (INIS)

    Carson, R.S.; Vlases, G.C.

    1983-01-01

    The experimental facility is a 21-cm-long solenoid with a 5.5-cm bore. The 4-cm ID quartz tube is filled with slowly flowing H 2 to 0.5-3.0 torr. Fields up to 6.5 T in 3.7 μsec are produced, with reverse-bias fields up -1.9 T. Preionization is by 40kA axial discharge 4.5 μsec before field-reversal is begun. The CO 2 laser used produces 300 to 400 J in 2 μsec, in an annular beam that can be defocused for preheating the outer edges of the plasma, or focused tightly for central-column heating and beam propagation during formation. The focusing system includes a return mirror for multiple passing of the laser energy. Diagnostics include compensated, diamagnetic flux loops, internal field probes, cross-tube and axial interferometers, fast photography, and spectroscopy

  16. Plutonium decontamination studies using Reverse Osmosis

    International Nuclear Information System (INIS)

    Plock, C.E.; Travis, T.N.

    1980-01-01

    Water in batches of 45 gallons each, from a creek crossing the Rocky Flats Plant, was transferred to the Reverse Osmosis (RO) laboratory for experimental testing. The testing involved using RO for plutonium decontamination. For each test, the water was spiked with plutonium, had its pH adjusted, and was then processed by RO. At a water recovery level of 87%, the plutonium decontamination factors ranged from near 100 to 1200, depending on the pH of the processed water

  17. A Reverse Stroop Task with Mouse Tracking

    Science.gov (United States)

    Yamamoto, Naohide; Incera, Sara; McLennan, Conor T.

    2016-01-01

    In a reverse Stroop task, observers respond to the meaning of a color word irrespective of the color in which the word is printed—for example, the word red may be printed in the congruent color (red), an incongruent color (e.g., blue), or a neutral color (e.g., white). Although reading of color words in this task is often thought to be neither facilitated by congruent print colors nor interfered with incongruent print colors, this interference has been detected by using a response method that does not give any bias in favor of processing of word meanings or processing of print colors. On the other hand, evidence for the presence of facilitation in this task has been scarce, even though this facilitation is theoretically possible. By modifying the task such that participants respond to a stimulus color word by pointing to a corresponding response word on a computer screen with a mouse, the present study investigated the possibility that not only interference but also facilitation would take place in a reverse Stroop task. Importantly, in this study, participants’ responses were dynamically tracked by recording the entire trajectories of the mouse. Arguably, this method provided richer information about participants’ performance than traditional measures such as reaction time and accuracy, allowing for more detailed (and thus potentially more sensitive) investigation of facilitation and interference in the reverse Stroop task. These trajectories showed that the mouse’s approach toward correct response words was significantly delayed by incongruent print colors but not affected by congruent print colors, demonstrating that only interference, not facilitation, was present in the current task. Implications of these findings are discussed within a theoretical framework in which the strength of association between a task and its response method plays a critical role in determining how word meanings and print colors interact in reverse Stroop tasks. PMID:27199881

  18. Variable Cycle Intake for Reverse Core Engine

    Science.gov (United States)

    Suciu, Gabriel L (Inventor); Chandler, Jesse M (Inventor); Staubach, Joseph B (Inventor)

    2016-01-01

    A gas generator for a reverse core engine propulsion system has a variable cycle intake for the gas generator, which variable cycle intake includes a duct system. The duct system is configured for being selectively disposed in a first position and a second position, wherein free stream air is fed to the gas generator when in the first position, and fan stream air is fed to the gas generator when in the second position.

  19. Computational methods for reversed-field equilibrium

    International Nuclear Information System (INIS)

    Boyd, J.K.; Auerbach, S.P.; Willmann, P.A.; Berk, H.L.; McNamara, B.

    1980-01-01

    Investigating the temporal evolution of reversed-field equilibrium caused by transport processes requires the solution of the Grad-Shafranov equation and computation of field-line-averaged quantities. The technique for field-line averaging and the computation of the Grad-Shafranov equation are presented. Application of Green's function to specify the Grad-Shafranov equation boundary condition is discussed. Hill's vortex formulas used to verify certain computations are detailed. Use of computer software to implement computational methods is described

  20. Reversible thyristor converters of brushless synchronous compensators

    Directory of Open Access Journals (Sweden)

    А.М.Galynovskiy

    2013-12-01

    Full Text Available Behavior of models of three-phase-to-single-phase rotary reversible thyristor converters of brushless synchronous compensators in a circuit simulation system is analyzed. It is shown that combined control mode of opposite-connected thyristors may result in the exciter armature winding short circuits both at the thyristor feed-forward and lagging current delay angles. It must be taken into consideration when developing brushless compensator excitation systems.

  1. Forward and reverse mutagenesis in C. elegans

    Science.gov (United States)

    Kutscher, Lena M.; Shaham, Shai

    2014-01-01

    Mutagenesis drives natural selection. In the lab, mutations allow gene function to be deciphered. C. elegans is highly amendable to functional genetics because of its short generation time, ease of use, and wealth of available gene-alteration techniques. Here we provide an overview of historical and contemporary methods for mutagenesis in C. elegans, and discuss principles and strategies for forward (genome-wide mutagenesis) and reverse (target-selected and gene-specific mutagenesis) genetic studies in this animal. PMID:24449699

  2. Particle transort in field-reversed configurations

    Energy Technology Data Exchange (ETDEWEB)

    Tuszewski, M.; Linford, R.K.; Lipson, J.; Sgro, A.G.

    1981-01-01

    A field reversed configuration (FRC) is a compact toroid that contains no toroidal field. These plasmas are observed to be grossly stable for about 10-100 ..mu..sec. The lifetimes appear limited by an n = 2 rotational instability which may be caused by particle loss. Particle transport is therefore an important issue for these configurations. We investigate particle loss with a steady-state, 1-D model which approximates the experimental observation of elongated FRC equilibrium with about constant separatrix radius.

  3. On the design of reversible QDCA systems.

    Energy Technology Data Exchange (ETDEWEB)

    DeBenedictis, Erik P.; Frank, Michael P. (Florida State University, Tallahassee, FL); Ottavi, Marco; Frost-Murphy, Sarah E. (University of Notre Dame, Notre Dame, IN)

    2006-10-01

    This work is the first to describe how to go about designing a reversible QDCA system. The design space is substantial, and there are many questions that a designer needs to answer before beginning to design. This document begins to explicate the tradeoffs and assumptions that need to be made and offers a range of approaches as starting points and examples. This design guide is an effective tool for aiding designers in creating the best quality QDCA implementation for a system.

  4. Evaluating Reverse Supply Chain Efficiency: Manufacturer's Perspective

    DEFF Research Database (Denmark)

    Kumar, M.; Tiwari, M. K.; Wong, K. Y.

    2014-01-01

    The paper aims to illustrate the use of fuzzy data envelopment analysis (DEA) in analyzing reverse supply chain (RSC) performance from the manufacturer's perspective. By using an alternative alpha-cut approach, the fuzzy DEA model was converted into a crisp linear programming problem, thereby...... usually ensures an environmentally friendly supply chain network, companies which have implemented RSC techniques since a longer duration do not necessarily have a more efficient supply chain in general....

  5. Clinical Applications of Reverse Panoramic Radiography

    Directory of Open Access Journals (Sweden)

    Sujatha S Reddy

    2011-09-01

    Full Text Available The essence of oral and maxil-lofacial radiology is not only to be an important tool in the diagnostic assessment of dental patients but also to equip the clinician with the ability to interpret images of certain maxillocraniofacial structures of importance to dental, medical and surgical practices. Although combinations of several conven-tional x-ray projections can be adequate in a number of clinical situations, radiographic assessment of certain craniofacial structures some-times needs to be facilitated by other imaging modalities. A not-so-recent development called reverse panoramic radiography may be a useful adjuvant to such a situation, at least in the near future. It is essentially a technique where the patient is placed backwards in the panoramic machine in a reverse position in such a way that x-ray beam is directed through the patient’s face and the exit beam then passes through the patient’s head on the opposite side where it is captured on the receptor. The following manuscript is an attempt to throw light on this technique and the impact it may have on dental, medical and surgical practices. The advantages and disadvantages of reverse panoramic radiography and it’s comparison to conventional panoramic radiographs and other skull views are also dis-cussed.

  6. Earth's magnetic field is probably not reversing.

    Science.gov (United States)

    Brown, Maxwell; Korte, Monika; Holme, Richard; Wardinski, Ingo; Gunnarson, Sydney

    2018-04-30

    The geomagnetic field has been decaying at a rate of [Formula: see text]5% per century from at least 1840, with indirect observations suggesting a decay since 1600 or even earlier. This has led to the assertion that the geomagnetic field may be undergoing a reversal or an excursion. We have derived a model of the geomagnetic field spanning 30-50 ka, constructed to study the behavior of the two most recent excursions: the Laschamp and Mono Lake, centered at 41 and 34 ka, respectively. Here, we show that neither excursion demonstrates field evolution similar to current changes in the geomagnetic field. At earlier times, centered at 49 and 46 ka, the field is comparable to today's field, with an intensity structure similar to today's South Atlantic Anomaly (SAA); however, neither of these SAA-like fields develop into an excursion or reversal. This suggests that the current weakened field will also recover without an extreme event such as an excursion or reversal. The SAA-like field structure at 46 ka appears to be coeval with published increases in geomagnetically modulated beryllium and chlorine nuclide production, despite the global dipole field not weakening significantly in our model during this time. This agreement suggests a greater complexity in the relationship between cosmogenic nuclide production and the geomagnetic field than is commonly assumed.

  7. Domino model for geomagnetic field reversals.

    Science.gov (United States)

    Mori, N; Schmitt, D; Wicht, J; Ferriz-Mas, A; Mouri, H; Nakamichi, A; Morikawa, M

    2013-01-01

    We solve the equations of motion of a one-dimensional planar Heisenberg (or Vaks-Larkin) model consisting of a system of interacting macrospins aligned along a ring. Each spin has unit length and is described by its angle with respect to the rotational axis. The orientation of the spins can vary in time due to spin-spin interaction and random forcing. We statistically describe the behavior of the sum of all spins for different parameters. The term "domino model" in the title refers to the interaction among the spins. We compare the model results with geomagnetic field reversals and dynamo simulations and find strikingly similar behavior. The aggregate of all spins keeps the same direction for a long time and, once in a while, begins flipping to change the orientation by almost 180 degrees (mimicking a geomagnetic reversal) or to move back to the original direction (mimicking an excursion). Most of the time the spins are aligned or antialigned and deviate only slightly with respect to the rotational axis (mimicking the secular variation of the geomagnetic pole with respect to the geographic pole). Reversals are fast compared to the times in between and they occur at random times, both in the model and in the case of the Earth's magnetic field.

  8. Navigation of the autonomous vehicle reverse movement

    Science.gov (United States)

    Rachkov, M.; Petukhov, S.

    2018-02-01

    The paper presents a mathematical formulation of the vehicle reverse motion along a multi-link polygonal trajectory consisting of rectilinear segments interconnected by nodal points. Relevance of the problem is caused by the need to solve a number of tasks: to save the vehicle in the event of а communication break by returning along the trajectory already passed, to avoid a turn on the ground in constrained obstacles or dangerous conditions, or a partial return stroke for the subsequent bypass of the obstacle and continuation of the forward movement. The method of navigation with direct movement assumes that the reverse path is elaborated by using landmarks. To measure landmarks on board, a block of cameras is placed on a vehicle controlled by the operator through the radio channel. Errors in estimating deviation from the nominal trajectory of motion are determined using the multidimensional correlation analysis apparatus based on the dynamics of a lateral deviation error and a vehicle speed error. The result of the experiment showed a relatively high accuracy in determining the state vector that provides the vehicle reverse motion relative to the reference trajectory with a practically acceptable error while returning to the start point.

  9. Preference reversal in quantum decision theory

    Directory of Open Access Journals (Sweden)

    Vyacheslav I. Yukalov

    2015-10-01

    Full Text Available We consider the psychological effect of preference reversal and showthat it finds a natural explanation in the frame of quantum decisiontheory. When people choose between lotteries with non-negative payoffs, they prefer a more certain lottery because of uncertainty aversion. But when people evaluate lottery prices, e.g. for selling to others the right to play them, they do this more rationally, being less subject to behavioral biases. This difference can be explained bythe presence of the attraction factors entering the expression of quantumprobabilities. Only the existence of attraction factors can explain why,considering two lotteries with close utility factors, a decision maker prefers one of them when choosing, but evaluates higher the other one when pricing. We derive a general quantitative criterion for the preference reversal to occur that relates the utilities of the two lotteries to the attraction factors under choosing versus pricing and test successfully its application on experiments by Tversky et al.We also show that the planning paradox can be treated as a kind of preference reversal.

  10. Alfven eigenmodes in shear reversed plasmas

    International Nuclear Information System (INIS)

    Breizman, B.N.; Berk, H.L.; Pekker, M.S.; Sharapov, S.E.; Hawkes, N.C.; Borba, D.N.; Pinches, S.D.

    2003-01-01

    Experiments on JT-60U and JET have shown that plasma configurations with shear reversal are prone to the excitation of unusual Alfven Eigenmodes by energetic particles. These modes emerge outside the TAE frequency gap, where one might expect them to be strongly damped. The modes often appear in bunches and they exhibit a quasi-periodic pattern of predominantly upward frequency sweeping (Alfven Cascades) as the safety factor q changes in time. This work presents a theory that explains the key features of the observed unusual modes including their connection to TAE's as well as the modifications of TAE's themselves near the shear reversal point. The developed theory has been incorporated into a reduced numerical model and verified with full geometry codes. JET experimental data on Alfven spectroscopy have been simulated to infer the mode numbers and the evolution of q min in the discharge. This analysis confirms the values of q that characterize the internal transport barrier triggering in reversed shear plasmas. (author)

  11. Model of reversible vesicular transport with exclusion

    International Nuclear Information System (INIS)

    Bressloff, Paul C; Karamched, Bhargav R

    2016-01-01

    A major question in neurobiology concerns the mechanics behind the motor-driven transport and delivery of vesicles to synaptic targets along the axon of a neuron. Experimental evidence suggests that the distribution of vesicles along the axon is relatively uniform and that vesicular delivery to synapses is reversible. A recent modeling study has made explicit the crucial role that reversibility in vesicular delivery to synapses plays in achieving uniformity in vesicle distribution, so called synaptic democracy (Bressloff et al 2015 Phys. Rev. Lett. 114 168101). In this paper we generalize the previous model by accounting for exclusion effects (hard-core repulsion) that may occur between molecular motor-cargo complexes (particles) moving along the same microtubule track. The resulting model takes the form of an exclusion process with four internal states, which distinguish between motile and stationary particles, and whether or not a particle is carrying vesicles. By applying a mean field approximation and an adiabatic approximation we reduce the system of ODEs describing the evolution of occupation numbers of the sites on a 1D lattice to a system of hydrodynamic equations in the continuum limit. We find that reversibility in vesicular delivery allows for synaptic democracy even in the presence of exclusion effects, although exclusion does exacerbate nonuniform distributions of vesicles in an axon when compared with a model without exclusion. We also uncover the relationship between our model and other models of exclusion processes with internal states. (paper)

  12. Magnetization reversal in single molecule magnets

    Science.gov (United States)

    Bokacheva, Louisa

    2002-09-01

    I have studied the magnetization reversal in single molecule magnets (SMMs). SMMs are Van der Waals crystals, consisting of identical molecules containing transition metal ions, with high spin and large uniaxial magnetic anisotropy. They can be considered as ensembles of identical, iso-oriented nanomagnets. At high temperature, these materials behave as superparamagnets and their magnetization reversal occurs by thermal activation. At low temperature they become blocked, and their magnetic relaxation occurs via thermally assisted tunneling or pure quantum tunneling through the anisotropy barrier. We have conducted detailed experimental studies of the magnetization reversal in SMM material Mn12-acetate (Mn12) with S = 10. Low temperature measurements were conducted using micro-Hall effect magnetometry. We performed hysteresis and relaxation studies as a function of temperature, transverse field, and magnetization state of the sample. We identified magnetic sublevels that dominate the tunneling at a given field, temperature and magnetization. We observed a crossover between thermally assisted and pure quantum tunneling. The form of this crossover depends on the magnitude and direction of the applied field. This crossover is abrupt (first-order) and occurs in a narrow temperature interval (tunneling mechanisms in Mn12.

  13. Reversal of multidrug resistance by surfactants.

    Science.gov (United States)

    Woodcock, D. M.; Linsenmeyer, M. E.; Chojnowski, G.; Kriegler, A. B.; Nink, V.; Webster, L. K.; Sawyer, W. H.

    1992-01-01

    Cremophor EL, a pharmacologically inactive solubilising agent, has been shown to reverse multidrug resistance (MDR). Using flow cytometric evaluation of equilibrium intracellular levels of daunorubicin (DNR), we found that eight other surface active agents will also reverse MDR. All the active detergents contain polyethoxylated moieties but have no similarities in their hydrophobic components. The properties of three polyethoxylated surfactants that showed the lowest toxicities, Cremophor, Tween 80 and Solutol HS15, were examined in more detail. The concentrations of Tween 80 and Solutol required to reverse DNR exclusion were 10-fold lower than for Cremophor. However while concentrations greater than or equal to 1:10(2) of the former two surfactants resulted in breakdown of cells, even 1:10 of Cremophor did not lyse cells. Studies of the effects of Cremophor on the uptake and efflux of DNR in normal and MDR cell types showed that Cremophor increases intracellular DNR primarily by locking the rapid efflux from the cells. This blockage of drug efflux may be mediated by a substantial alteration in the fluidity of cell membranes induced by Cremophor, as shown by decreased fluorescence anisotropy of a membrane probe. Consistent with these data, coinjection of adriamycin plus Cremophor into mice carrying a multidrug resistant P388 transplantable tumour significantly increased the survival time of the mice compared with adriamycin treatment alone. PMID:1637678

  14. Preference reversal in quantum decision theory

    Science.gov (United States)

    Yukalov, Vyacheslav I.; Sornette, Didier

    2015-01-01

    We consider the psychological effect of preference reversal and show that it finds a natural explanation in the frame of quantum decision theory. When people choose between lotteries with non-negative payoffs, they prefer a more certain lottery because of uncertainty aversion. But when people evaluate lottery prices, e.g., for selling to others the right to play them, they do this more rationally, being less subject to behavioral biases. This difference can be explained by the presence of the attraction factors entering the expression of quantum probabilities. Only the existence of attraction factors can explain why, considering two lotteries with close utility factors, a decision maker prefers one of them when choosing, but evaluates higher the other one when pricing. We derive a general quantitative criterion for the preference reversal to occur that relates the utilities of the two lotteries to the attraction factors under choosing vs. pricing and test successfully its application on experiments by Tversky et al. We also show that the planning paradox can be treated as a kind of preference reversal. PMID:26500592

  15. Reversible logic synthesis methodologies with application to quantum computing

    CERN Document Server

    Taha, Saleem Mohammed Ridha

    2016-01-01

    This book opens the door to a new interesting and ambitious world of reversible and quantum computing research. It presents the state of the art required to travel around that world safely. Top world universities, companies and government institutions  are in a race of developing new methodologies, algorithms and circuits on reversible logic, quantum logic, reversible and quantum computing and nano-technologies. In this book, twelve reversible logic synthesis methodologies are presented for the first time in a single literature with some new proposals. Also, the sequential reversible logic circuitries are discussed for the first time in a book. Reversible logic plays an important role in quantum computing. Any progress in the domain of reversible logic can be directly applied to quantum logic. One of the goals of this book is to show the application of reversible logic in quantum computing. A new implementation of wavelet and multiwavelet transforms using quantum computing is performed for this purpose. Rese...

  16. Photonics of dyes molecules in reverse micellar solution

    International Nuclear Information System (INIS)

    Ibragimova, M.R.; Laurinas, V.Ch.

    2001-01-01

    Spectral luminescent characteristics of the dye acridine orange and eosin has been studied in reverse micellar solutions of sodium bis(2-ethyl-hexyl)sulfosuccinate. It was shown that the increase of the nucleus volume of reverse micelles. (author)

  17. Long-acting reversible hormonal contraception | Dahan-Farkas ...

    African Journals Online (AJOL)

    Long-acting reversible hormonal contraceptives are effective methods of birth control that provide contraception for an extended period without requiring user action. Long-acting reversible hormonal contraceptives include progesterone only injectables, subdermal implants and the levonorgestrel intrauterine system.

  18. The Role of Reverse Logistics on the European Market

    OpenAIRE

    Irina Tobosaru; Irina Nicolau

    2009-01-01

    The Council of Logistics Management has published the first definition of reverse logistics in 1992: “The term reverse logistics refers to the role of logistics in recycling waste, in the distribution and the handling of dangerous materials. A broader definition includes in the reverse logistics, activities that have the purpose of reducing the resources, of recycling, replacing, reusing the materials and relocating them”. Reverse logistics can be also defined using as standard the definition...

  19. Reversible and non-reversible enlargement of cerebral spinal fluid spaces in anorexia nervosa

    International Nuclear Information System (INIS)

    Artmann, H.; Grau, H.; Adelmann, M.; Schleiffer, R.

    1985-01-01

    Brain CT studies of 35 patients with anoxia nervosa confirmed the observations of other authors: cerebral dystrophic changes correlate with weight loss and the reversibility of these changes also correlates with the normalization of body weight. Other corroborated facts are: the most numerous and most pronounced enlargements are of the cortical sulci and the interhemispheric fissure, moderate widening affects the ventricles and the rarest and most insignificant changes are those of the cerebellum. The reversibility of the changes showed a parallel to the extent of the changes themselves and to the duration of improvement of the body weight. The reversibility of the enlargement of the cortical sulci and of the distances between the frontal horns of the lateral ventricles was more often significant than that of the abnormal measurements of the cella media. This difference is based on minimal early acquired brain damage which occurs in 60% of our patients. This high incidence of early acquired minimal brain disease in patients with anorexia nervosa is here discussed as a nonspecific predisposing factor. Although there is no exact explanation of the etiology of the reversible enlargement of cerenral spinal fluid (CSF) spaces in anorexia nervosa, the changes resemble those in alcoholics. The mechanisms of brain changes in alcoholism, as shown experimentally, seem to us to throw light on the probable mechanism of reversible dystrophic brain changes in anorexia nervosa. (orig.)

  20. Reversible and non-reversible enlargement of cerebral spinal fluid spaces in anorexia nervosa

    Energy Technology Data Exchange (ETDEWEB)

    Artmann, H.; Grau, H.; Adelmann, M.; Schleiffer, R.

    1985-07-01

    Brain CT studies of 35 patients with anoxia nervosa confirmed the observations of other authors: cerebral dystrophic changes correlate with weight loss and the reversibility of these changes also correlates with the normalization of body weight. Other corroborated facts are: the most numerous and most pronounced enlargements are of the cortical sulci and the interhemispheric fissure, moderate widening affects the ventricles and the rarest and most insignificant changes are those of the cerebellum. The reversibility of the changes showed a parallel to the extent of the changes themselves and to the duration of improvement of the body weight. The reversibility of the enlargement of the cortical sulci and of the distances between the frontal horns of the lateral ventricles was more often significant than that of the abnormal measurements of the cella media. This difference is based on minimal early acquired brain damage which occurs in 60% of our patients. This high incidence of early acquired minimal brain disease in patients with anorexia nervosa is here discussed as a nonspecific predisposing factor. Although there is no exact explanation of the etiology of the reversible enlargement of cerenral spinal fluid (CSF) spaces in anorexia nervosa, the changes resemble those in alcoholics. The mechanisms of brain changes in alcoholism, as shown experimentally, seem to us to throw light on the probable mechanism of reversible dystrophic brain changes in anorexia nervosa.

  1. Application of reverse osmosis in radioactive wastewater treatment

    International Nuclear Information System (INIS)

    Kong Jinsong; Guo Weiqun

    2012-01-01

    Considering the disadvantages of the conventional evaporation and ion exchange process for radioactive wastewater treatment, the reverse osmosis is used to treat the low level radioactive wastewater. The paper summarizes the research and application progress of the reverse osmosis in the radioactive wastewater treatment and indicates that the reverse osmosis in the radioactive wastewater treatment is very important. (authors)

  2. 21 CFR 177.2550 - Reverse osmosis membranes.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Reverse osmosis membranes. 177.2550 Section 177... Components of Articles Intended for Repeated Use § 177.2550 Reverse osmosis membranes. Substances identified in paragraph (a) of this section may be safely used as reverse osmosis membranes intended for use in...

  3. Wavefront reversal in a copper vapor active medium

    Energy Technology Data Exchange (ETDEWEB)

    Bunkin, F.V.; Savranskii, V.V.; Shafeev, G.A.

    1981-09-01

    Wavefront reversal in the resonator of a copper vapor laser was observed. The frequencies of the signal and reversed waves were the same. The dependence of the reversed signal power on the input signal power had a threshold. Photographs were obtained of the reconstructed image of an object when a distorting phase plate was inserted in the resonator.

  4. Reversal Negativity and Bistable Stimuli: Attention, Awareness, or Something Else?

    Science.gov (United States)

    Intaite, Monika; Koivisto, Mika; Ruksenas, Osvaldas; Revonsuo, Antti

    2010-01-01

    Ambiguous (or bistable) figures are visual stimuli that have two mutually exclusive perceptual interpretations that spontaneously alternate with each other. Perceptual reversals, as compared with non-reversals, typically elicit a negative difference called reversal negativity (RN), peaking around 250 ms from stimulus onset. The cognitive…

  5. Impact of biological therapy on body composition of patients with Chron's disease

    Directory of Open Access Journals (Sweden)

    Julianne Campos dos Santos

    Full Text Available Summary Introduction: Protein-energy malnutrition in Crohn's disease (CD has been reported in 20 to 92% of patients, and is associated with increased morbidity and mortality and higher costs for the health system. Anti-TNF drugs are a landmark in the clinical management, promoting prolonged remission in patients with CD. It is believed that the remission of this disease leads to nutritional recovery. The effect of biological therapy on body composition and nutritional status is unclear. Method: Prospective study of body assessment by bioelectrical impedance method in patients with moderate to severe CD undergoing treatment with infliximab. The main outcome was the body composition before and after 6 months of anti-TNF therapy. Results: There was a predominance of females (52% with a mean age of 42±12 years. Most patients were eutrophic at baseline and remained so. There was an increase in all parameters of body composition after anti-TNF treatment: BMI (22.9±3.2 versus 25±3.8; p=0.005, waist circumference (88.1±6.7 versus 93.9±7.7; p=0.002, lean mass index (17.5±2.2 versus 18.2±2.3; p=0.000 and fat mass index (5.5±2.3 versus 6.8±2.3; p=0.000. Phase angle remained unchanged (6.2 versus 6.8; p=0.94. Conclusion: After therapy with IFX, all components of body composition increased, except for phase angle. The substantial increase in fat mass index and waist circumference led to concern regarding cardiovascular risk and, thus, to the need for further studies.

  6. Advanced Modulation Formats in Cognitive Optical Networks: EU project CHRON Demonstration

    DEFF Research Database (Denmark)

    Borkowski, Robert; Caballero Jambrina, Antonio; Klonidis, Dimitris

    2014-01-01

    We demonstrate real-time path establishment and switching of coherent modulation formats (QPSK, 16QAM) within an optical network driven by cognitive algorithms. Cognition aims at autonomous configuration optimization to satisfy quality of transmission requirements.......We demonstrate real-time path establishment and switching of coherent modulation formats (QPSK, 16QAM) within an optical network driven by cognitive algorithms. Cognition aims at autonomous configuration optimization to satisfy quality of transmission requirements....

  7. Reversal permanent charge and reversal potential: case studies via classical Poisson–Nernst–Planck models

    International Nuclear Information System (INIS)

    Eisenberg, Bob; Liu, Weishi; Xu, Hongguo

    2015-01-01

    In this work, we are interested in effects of a simple profile of permanent charges on ionic flows. We determine when a permanent charge produces current reversal. We adopt the classical Poisson–Nernst–Planck (PNP) models of ionic flows for this study. The starting point of our analysis is the recently developed geometric singular perturbation approach for PNP models. Under the setting in the paper for case studies, we are able to identify a single governing equation for the existence and the value of the permanent charge for a current reversal. A number of interesting features are established. The related topic on reversal potential can be viewed as a dual problem and is briefly examined in this work too. (paper)

  8. Resultados paleomagnéticos de los depósitos pliopleistocenos de la cuenca de Palma (Mallorca, España

    Directory of Open Access Journals (Sweden)

    Silva, P. G.

    2000-08-01

    Full Text Available The results from the paleomagnetic analysis of the plio-pleistocene deposits located in the eastern (Bahia Azul Section and western (Banc d'Eivissa borders of the Palma Basin are presented in this paper. The Bahía Azul section is composite by a marine terrace at +70-74 m a.s.1., overlapped by nine littoral dune systems separated by erosional surfaces. The Banc d'Eivissa section is constituted of a lower marine terrace at +24-25 m a.s.l., buried by two dune systems, although there are more numerous in the vicinity. The lithological spectrum at both sections holds a main calcarenitic nature, but the available outcrops display a different degree of weathering making difficult the establishment of a continuous magnetoestratigraphic sequence. The paleontological content (Roselló y Cuerda, 1973 and paleomagnetic results of the Banc d'Eivissa deposits are no sufficient to establish a precise chronological sequence, and only is possible to locate them within the reverse polarity Matuyama epoch. On the contrary, the lower half of the Bahia Azul sequence (marine terrace plus the 3 first dune systems presents a consistent reverse polarity. The paleontological content of these materials indicates an early Pleistocene age (Emilian cycle: Cuerda y Sacarés, 1992 which agree with the obtained paleomagnetic results. Therefore, the whole sequence is interpreted to be located between the normal polarity chrons of Jaramillo and Olduvay (Clr. 1n and C2n of Cande and Kent, 1995 within the Matuyama epoch, but can not be totally rejected the possibility that them could be placed after the Olduvai Chron.Se presentan los resultados paleomagnéticos obtenidos del análisis de los depósitos plio-pleistocenos que afloran en los bordes oriental (sección de Bahía Azul y occidental (Banc d'Eivissa de la cuenca de Palma. La sección de Bahía Azul está constituida por una terraza marina situada a +70-74 metros sobre el nivel medio del mar y, sobre ella, nueve sistemas

  9. Reversed straining in axisymmetric compression test

    DEFF Research Database (Denmark)

    Arentoft, Mogens; Wanheim, Tarras; Lindegren, Maria

    2005-01-01

    A large group of the cold forging processes is carried out in a thick – walled container with the deformation force transmitted through a punch moving axially in the container. The work piece, being entrapped between punch and container will expand and exert a radial pressure resulting in an expa...... to simulate these conditions a reversed axisymmetrical material tester is designed and constructed. Three different materials were tested, aluminum alloy AA6082, technically pure copper (99.5%) and cold forging steel Ma8, at different temperatures found during cold forging....

  10. Idaho Power's reverses decline with employee increase

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Following several years of decline, the number of full-time Idaho Power employees increased to 1,528 at the end of 1989, up from 1,500 in 1988. The increase reversed a steady decline that began in 1984 when the company had a peak employment of 1,725. Last year's increase in the work force in part reflects recent additions in customers served and the electric demands of an expanding economy in the service area, as well as new regulatory requirements, the company said

  11. Field reversal produced by a plasma gun

    International Nuclear Information System (INIS)

    Hartman, C.W.; Condit, W.; Granneman, E.H.A.; Prono, D.; Smith, A.C. Jr.; Taska, J.; Turner, W.C.

    1980-01-01

    Experimental results are presented of the production of Field-Reversed Plasma with a high energy coaxial plasma gun. The gun is magnetized with solenoids inside the center electrode and outside the outer electrode so that plasma emerging from the gun entrains the radial fringer field at the muzzle. The plasma flow extends field lines propagating a high electrical conductivity, the flux inside the center electrode should be preserved. However, for low flux, the trapped flux exceeds by 2 or more the initial flux, possibly because of helical deformation of the current channel extending from the center electrode

  12. A Reverse Stroop Task with Mouse Tracking

    OpenAIRE

    Yamamoto, Naohide; Incera, Sara; McLennan, Conor T.

    2016-01-01

    In a reverse Stroop task, observers respond to the meaning of a color word irrespective of the color in which the word is printed—for example, the word red may be printed in the congruent color (red), an incongruent color (e.g., blue), or a neutral color (e.g., white). Although reading of color words in this task is often thought to be neither facilitated by congruent print colors nor interfered with incongruent print colors, this interference has been detected by using a response method that...

  13. Focusing over Optical Fiber Using Time Reversal

    DEFF Research Database (Denmark)

    Piels, Molly; Porto da Silva, Edson; Estaran Tolosa, Jose Manuel

    2015-01-01

    A time-reversal array in multimode fiber is proposed for lossless remotely controlled switching using passive optical splitters. The signal to be transmitted is digitally pre-distorted so that it is routed through the physical layer in order to arrive at only one receiver in an array. System...... performance in the presence of additive white gaussian noise, modal group delay, and timing error is investigated numerically for single-mode and 10-mode fiber. Focusing using a two-transmitter array and 44 km of single- mode fiber is demonstrated experimentally for 3 GBd QPSK signals with a bit error rate...

  14. Reversibility and retrievability - What is the question?

    International Nuclear Information System (INIS)

    Taylor, D.M.; Webster, S.

    2002-01-01

    Retrievability has become a very fashionable concept in recent years, undoubtedly as a result of the possible advantages regarding public acceptance. However, in this 'rush to retrieve' we must not lose sight of the fundamental principles that form the basis of any proposed strategy of geological disposal of high-level radioactive waste. This paper takes a 'matter of fact' look at retrievability and the more general issue of reversibility in the context of geological disposal and draws a number of clear and concise conclusions on the subject. (author)

  15. Reversible fatty infiltration of the liver

    International Nuclear Information System (INIS)

    Bostel, F.; Hauger, W.

    1987-01-01

    Case studies show that acute pancreatitis occurring independently or combined with a preceding abuse of alcohol may be the cause of fatty infiltration of the liver. These fat areas can evolve in a very short time and provoke in the case of focal incidence diagnostic problems of differentiation against abscesses of metastases. Due to this fact and because of the rapid reversibility of the fatty infiltration under therapy, the safest method to clarify the situation consists of short-term CT controls. (orig.) [de

  16. Kinetic Stability of the Field Reversed Configuration

    International Nuclear Information System (INIS)

    E.V. Belova; R.C. Davidson; H. Ji; and M. Yamada

    2002-01-01

    New computational results are presented which advance the understanding of the stability properties of the Field-Reversed Configuration (FRC). The FRC is an innovative confinement approach that offers a unique fusion reactor potential because of its compact and simple geometry, translation properties, and high plasma beta. One of the most important issues is FRC stability with respect to low-n (toroidal mode number) MHD modes. There is a clear discrepancy between the predictions of standard MHD theory that many modes should be unstable on the MHD time scale, and the observed macroscopic resilience of FRCs in experiments

  17. Understanding Virtual Objects through Reverse Engineering

    Directory of Open Access Journals (Sweden)

    Vera Moitinho

    2012-11-01

    Full Text Available The main objective of our research is to develop a new methodology, based on Reverse Engineering processes – 3D scan, quantitative data analysis and Artificial Intelligence techniques, in particular simulation – to study the relationship between form and function of artefacts. Furthermore, we aim to provide new data, as well as possible explanations of the archaeological record according to what it expects about social activity, including working processes, by simulating the potentialities of such actions in terms of input-output relationships.

  18. Reverse triiodothyronine in protein energy malnutrition

    Energy Technology Data Exchange (ETDEWEB)

    Hafiez, A A; Abdel-Salam, E; Abbas, E Z; Halawa, F A; El-Hefnawy, N [Cairo Univ. (Egypt)

    1984-08-01

    Serum levels of thyroxine (T/sub 4/), triiodothyronine (T/sub 3/), reverse triiodothyronine (rT/sub 3/) and thyrotropin (TSH) were determined in cases of kwashiorkor and marasmus. Decreased levels of T/sub 4/ and T/sub 3/, and increased levels of rT/sub 3/ with no change in TSH were obtained. Thus in infants suffering from protein energy malnutrition there is a state of thyroid dysfunction as well as a shift in the peripheral T/sub 4/ metabolism being converted to the inert rT/sub 3/ rather than to the physiologically active T/sub 3/.

  19. Legal and Regulatory Barriers to Reverse Innovation.

    Science.gov (United States)

    Rowthorn, Virginia; Plum, Alexander J; Zervos, John

    Reverse innovation, or the importation of new, affordable, and efficacious models to high-income countries from the developing world, has emerged as a way to improve the health care system in the United States. Reverse innovation has been identified as a key emerging trend in global health systems in part because low-resourced settings are particularly good laboratories for low-cost/high-impact innovations that are developed out of necessity. A difficult question receiving scant attention is that of legal and regulatory barriers. The objective of this paper is to understand and elucidate the legal barriers faced by innovators bringing health interventions to the United States. Semistructured qualitative interviews were conducted with 9 key informants who have directly participated in the introduction of global health care approaches to the United States health system. A purposive sampling scheme was employed to identify participants. Phone interviews were conducted over one week in July 2016 with each participant and lasted an average of 35 minutes each. Purely legal barriers included questions surrounding tort liability, standard of care, and concerns around patient-administered self-care. Regulatory burdens included issues of international medical licensure, reimbursement, and task shifting and scope of work challenges among nonprofessionals (e.g. community health workers). Finally, perceived (i.e. not realized or experienced) legal and regulatory barriers to innovative modalities served as disincentives to bringing products or services developed outside of the United States to the United States market. Conflicting interests within the health care system, safety concerns, and little value placed on low-cost interventions inhibit innovation. Legal and regulatory barriers rank among, and contribute to, an anti-innovation atmosphere in healthcare for domestic and reverse innovators alike. Reverse innovation should be fostered through the thoughtful development of

  20. Some factors affecting time reversal signal reconstruction

    Czech Academy of Sciences Publication Activity Database

    Převorovský, Zdeněk; Kober, Jan

    2015-01-01

    Roč. 70, September (2015), s. 604-608 ISSN 1875-3892. [ICU International Congress on Ultrasonics 2015. Metz, 10.05.2015-15.05.2015] Institutional support: RVO:61388998 Keywords : nondestructive testing * time reversal signal processing * ultrasonic source reconstruction * acoustic emission * coda wave interferometry Subject RIV: BI - Acoustic s http://ac.els-cdn.com/S1875389215007762/1-s2.0-S1875389215007762-main.pdf?_tid=1513a4a2-9e5b-11e5-9693-00000aab0f27&acdnat=1449655153_455a4e32a1135236d0796c3f973ff58e

  1. Reversed rainbow with a nonlocal metamaterial

    Energy Technology Data Exchange (ETDEWEB)

    Morgado, Tiago A., E-mail: tiago.morgado@co.it.pt; Marcos, João S.; Silveirinha, Mário G., E-mail: mario.silveirinha@co.it.pt [Department of Electrical Engineering, Instituto de Telecomunicações, University of Coimbra, 3030 Coimbra (Portugal); Costa, João T. [CST AG, Bad Nauheimer Strasse 19, 64289 Darmstadt (Germany); Costa, Jorge R. [Instituto de Telecomunicações and Instituto Universitário de Lisboa (ISCTE-IUL), 1649-026 Lisboa (Portugal); Fernandes, Carlos A. [Instituto de Telecomunicações, and Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa (Portugal)

    2014-12-29

    One of the intriguing potentials of metamaterials is the possibility to realize a nonlocal electromagnetic reaction, such that the effective medium response at a given point is fundamentally entangled with the macroscopic field distribution at long distances. Here, it is experimentally and numerically verified that a microwave nonlocal metamaterial formed by crossed metallic wires enables a low-loss broadband anomalous material response such that the refractive index decreases with frequency. Notably, it is shown that an electromagnetic beam refracted by our metamaterial prism creates a reversed microwave rainbow.

  2. Intractable problems in reversible cellular automata

    International Nuclear Information System (INIS)

    Vatan, F.

    1988-01-01

    The billiard ball model, a classical mechanical system in which all parameters are real variables, can perform all digital computations. An eight-state, 11-neighbor reversible cellular automaton (an entirely discrete system in which all parameters are integer variables) can simulate this model. One of the natural problems for this system is to determine the shape of a container so that they initial specific distribution of gas molecules eventually leads to a predetermined distribution. This problem if PSPACE-complete. Related intractable and decidable problems are discussed as well

  3. SandBlaster: Reversing the Apple Sandbox

    OpenAIRE

    Deaconescu, Răzvan; Deshotels, Luke; Bucicoiu, Mihai; Enck, William; Davi, Lucas; Sadeghi, Ahmad-Reza

    2016-01-01

    In order to limit the damage of malware on Mac OS X and iOS, Apple uses sandboxing, a kernel-level security layer that provides tight constraints for system calls. Particularly used for Apple iOS, sandboxing prevents apps from executing potentially dangerous actions, by defining rules in a sandbox profile. Investigating Apple's built-in sandbox profiles is difficult as they are compiled and stored in binary format. We present SandBlaster, a software bundle that is able to reverse/decompile Ap...

  4. Reverse triiodothyronine in protein energy malnutrition

    International Nuclear Information System (INIS)

    Hafiez, A.A.; Abdel-Salam, E.; Abbas, E.Z.; Halawa, F.A.; El-Hefnawy, N.

    1984-01-01

    Serum levels of thyroxine (T 4 ), triiodothyronine (T 3 ), reverse triiodothyronine (rT 3 ) and thyrotropin (TSH) were determined in cases of kwashiorkor and marasmus. Decreased levels of T 4 and T 3 , and increased levels of rT 3 with no change in TSH were obtained. Thus in infants suffering from protein energy malnutrition there is a state of thyroid dysfunction as well as a shift in the peripheral T 4 metabolism being converted to the inert rT 3 rather than to the physiologically active T 3 . (author)

  5. Reversed-field multiple mirror concept

    International Nuclear Information System (INIS)

    Steinhauer, L.C.; Grossmann, W.; Seyler, C.E.

    1978-01-01

    The reversed-field multiple mirror (RFMM), is a promising technique for end-stoppering linear magnetic fusion plasmas. By this means the physics and engineering advantages of a linear plasma are gained while circumventing the endloss problem, allowing the projection of very short (less than or equal to 100 m) conceptual reactors. RFMM end-stoppering is accomplished by a string of closed field-line cells on the plasma column axis; these cells strongly retard the axial flow of particles and energy. We describe the reactor implications of the RFMM

  6. Confinement dynamics in the reversed field pinch

    International Nuclear Information System (INIS)

    Schoenberg, K.F.

    1988-01-01

    The study of basic transport and confinement dynamics is central to the development of the reversed field pinch (RFP) as a confinement concept. Thus, the goal of RFP research is to understand the connection between processes that sustain the RFP configuration and related transport/confinement properties. Recently, new insights into confinement have emerged from a detailed investigation of RFP electron and ion physics. These insights derive from the recognition that both magnetohydrodynamic (MHD) and electron kinetic effects play an important and strongly coupled role in RFP sustainment and confinement dynamics. In this paper, we summarize the results of these studies on the ZT-40M experiment. 8 refs

  7. Reversible cerebral vasconstriction syndrome: A case report

    International Nuclear Information System (INIS)

    Lee, Jeong Sub; Park, Ji Kang; Kim, Seung Hyoung; Jeong, Sun Young

    2013-01-01

    We report a 46-year-old woman patient with reversible cerebral vasoconstriction syndrome (RCVS). She presented with severe headache, multiple cerebral infarction, and multifocal severe stenosis in the intracranial arteries on magnetic resonance angiography (MRA). One month after the episode, a small bowel gastrointestinal stromal tumor (GIST) was incidentally detected during the evaluation of severe anemia and GIST was removed. Follow-up MRA was performed 3 months and 1 year after an initial attack of headache, and multifocal severe intracranial arterial stenotic lesions were completely resolved, she did not experience any episode of RCVS during the 2 years.

  8. Boron Removal in Seawater Reverse Osmosis System

    KAUST Repository

    Rahmawati, Karina

    2011-07-01

    Reverse osmosis successfully proves to remove more than 99% of solute in seawater, providing fresh water supply with satisfied quality. Due to some operational constraints, however, some trace contaminants removal, such as boron, cannot be achieved in one pass system. The stringent criterion for boron from World Health Organization (WHO) and Saudi Arabia local standard (0.5 mg/l) is hardly fulfilled by single pass sea water reverse osmosis (SWRO) plants. Some design processes have been proposed to deal with boron removal, but they are not economically efficient due to high energy and chemical consumption. The objective of this study was to study boron removal by different reverse osmosis membranes in two pH conditions, with and without antiscalant addition. Thus, it was expected to observe the possibility of operating single pass system and necessity to operate two pass system using low energy membrane. Five membrane samples were obtained from two different manufacturers. Three types of feed water pH were used, pH 8, pH 10, and pH 10 with antiscalant addition. Experiment was conducted in parallel to compare membrane performance from two manufacturers. Filtration was run with fully recycle mode for three days. Sample of permeate and feed were taken every 12 hours, and analyzed for their boron and TDS concentration. Membrane samples were also tested for their surface charge. The results showed that boron rejection increases as the feed pH increases. This was caused by dissociation of boric acid to negatively charged borate ion and more negatively charged membrane surface at elevated pH which enhance boron rejection. This study found that single pass reverse osmosis system, with and without elevating the pH, may not be possible to be applied because of two reasons. First, permeate quality in term of boron, does not fulfill WHO and local Saudi Arabia regulations. Second, severe scaling occurs due to operation in alkaline condition, since Ca and Mg concentration are

  9. Reversible cerebral vasconstriction syndrome: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Sub; Park, Ji Kang; Kim, Seung Hyoung; Jeong, Sun Young [Jeju National University Hospital, Jeju National University School of Medicine, Jeju (Korea, Republic of)

    2013-11-15

    We report a 46-year-old woman patient with reversible cerebral vasoconstriction syndrome (RCVS). She presented with severe headache, multiple cerebral infarction, and multifocal severe stenosis in the intracranial arteries on magnetic resonance angiography (MRA). One month after the episode, a small bowel gastrointestinal stromal tumor (GIST) was incidentally detected during the evaluation of severe anemia and GIST was removed. Follow-up MRA was performed 3 months and 1 year after an initial attack of headache, and multifocal severe intracranial arterial stenotic lesions were completely resolved, she did not experience any episode of RCVS during the 2 years.

  10. Reversed-Field Pinch plasma model

    International Nuclear Information System (INIS)

    Miley, G.H.; Nebel, R.A.; Moses, R.W.

    1979-01-01

    The stability of a Reversed-Field Pinch (RFP) is strongly dependent on the plasma profile and the confining sheared magnetic field. Magnetic diffusion and thermal transport produce changing conditions of stability. Despite the limited understanding of RFP transport, modelling is important to predict general trends and to study possible field programming options. To study the ZT-40 experiment and to predict the performance of future RFP reactors, a one-dimensional transport code has been developed. This code includes a linear, ideal MHD stability check based on an energy principle. The transport section integrates plasma profiles forward in time while the stability section periodically checks the stability of the evolving plasma profile

  11. Interchange stability of noncircular reversed field pinches

    International Nuclear Information System (INIS)

    Skinner, D.A.; Prager, S.C.; Todd, A.M.M.

    1987-08-01

    Interchange (Mercier) stability of toroidal reversed-field-pinch plasmas with noncircular cross-section is evaluated numerically. Marginally stable pressure profiles and beta values are produced. Most shapes, such as indented or vertically elongated, reduce stability by making the net magnetic curvature of the poloidal-field-dominated plasmas yet worse than that of the circle. Horizontally elongated plasmas slightly enhance stability beyond that of the circle as a result of increased shear produced by toroidicity. Such shear enhancement by the toroidal shift of magnetic surfaces might be exploited for future, more comprehensive studies

  12. Extreme reversed sexual dichromatism in a bird without sex role reversal.

    Science.gov (United States)

    Heinsohn, Robert; Legge, Sarah; Endler, John A

    2005-07-22

    Brilliant plumage is typical of male birds, reflecting differential enhancement of male traits when females are the limiting sex. Brighter females are thought to evolve exclusively in response to sex role reversal. The striking reversed plumage dichromatism of Eclectus roratus parrots does not fit this pattern. We quantify plumage color in this species and show that very different selection pressures are acting on males and females. Male plumage reflects a compromise between the conflicting requirements for camouflage from predators while foraging and conspicuousness during display. Females are liberated from the need for camouflage but compete for rare nest hollows.

  13. Reversible deep storage: reversibility options for storage in deep geological formations

    International Nuclear Information System (INIS)

    2009-01-01

    This report describes the definition approach to reversibility conditions, presents the main characteristics of high-activity and intermediate-activity long-lived wastes, describes the storage in deep geological formations (safety functions, general description of the storage centre), discusses the design options for the different types of wastes (container, storage module, handling processes, phenomenological analysis, monitoring arrangements) and the decision process in support reversibility (steering of the storage process, progressive development and step-by-step closing), and reports and discusses the researches concerning the memory of the storage site

  14. Elements of a Reversible Object-Oriented Language

    DEFF Research Database (Denmark)

    Schultz, Ulrik Pagh; Axelsen, Holger Bock

    2016-01-01

    This paper presents initial ideas for the design and implementation of a reversible object-oriented language based on extending Janus with object-oriented concepts such as classes that encapsulate behavior and state, inheritance, virtual dispatching, as well as constructors. We show that virtual...... dispatching is a reversible decision mechanism easily translatable to a standard reversible programming model such as Janus, and we argue that reversible management of state can be accomplished using reversible constructors. The language is implemented in terms of translation to standard Janus programs....

  15. On flow reversals in Rayleigh-Bénard convection

    International Nuclear Information System (INIS)

    Chandra, Mani; Verma, Mahendra K

    2011-01-01

    The dynamics of flow reversals are studied numerically using Fourier mode analysis. Our analysis shows that the Fourier modes represent the large-scale flows accurately. We observe that during the reversals, the amplitude of one of the large-scale modes vanishes, while another mode rises sharply, very similar to the cessation-led reversals observed earlier in experiments and numerical simulations. The Fourier coefficients of the RBC equations obey certain symmetries properties, which dictates which modes change sign in flow reversals. Based on our simulation results and symmetry properties of the Fourier modes, we provide a qualitative explanation for the flow reversals.

  16. Ageing, fragility and the reversibility window in bulk alloy glasses

    International Nuclear Information System (INIS)

    Chakravarty, S; Georgiev, D G; Boolchand, P; Micoulaut, M

    2005-01-01

    Non-reversing relaxation enthalpies (ΔH nr ) at glass transitions T g (x) in the P x Ge x Se 1-2x ternary display wide, sharp and deep global minima (∼0) in the 0.09 g s become thermally reversing. In this reversibility window, glasses are found not to age, in contrast to ageing observed for fragile glass compositions outside the window. Thermal reversibility and lack of ageing seem to be paradigms of self-organization which molecular glasses share with protein structures which repetitively and reversibly change conformation near T g and the folding temperature respectively. (letter to the editor)

  17. Quantum Vertex Model for Reversible Classical Computing

    Science.gov (United States)

    Chamon, Claudio; Mucciolo, Eduardo; Ruckenstein, Andrei; Yang, Zhicheng

    We present a planar vertex model that encodes the result of a universal reversible classical computation in its ground state. The approach involves Boolean variables (spins) placed on links of a two-dimensional lattice, with vertices representing logic gates. Large short-ranged interactions between at most two spins implement the operation of each gate. The lattice is anisotropic with one direction corresponding to computational time, and with transverse boundaries storing the computation's input and output. The model displays no finite temperature phase transitions, including no glass transitions, independent of circuit. The computational complexity is encoded in the scaling of the relaxation rate into the ground state with the system size. We use thermal annealing and a novel and more efficient heuristic \\x9Dannealing with learning to study various computational problems. To explore faster relaxation routes, we construct an explicit mapping of the vertex model into the Chimera architecture of the D-Wave machine, initiating a novel approach to reversible classical computation based on quantum annealing.

  18. Atmospheric helium and geomagnetic field reversals.

    Science.gov (United States)

    Sheldon, W. R.; Kern, J. W.

    1972-01-01

    The problem of the earth's helium budget is examined in the light of recent work on the interaction of the solar wind with nonmagnetic planets. It is proposed that the dominant mode of helium (He4) loss is ion pumping by the solar wind during geomagnetic field reversals, when the earth's magnetic field is very small. The interaction of the solar wind with the earth's upper atmosphere during such a period is found to involve the formation of a bow shock. The penetration altitude of the shock-heated solar plasma is calculated to be about 700 km, and ionization rates above this level are estimated for a cascade ionization (electron avalanche) process to average 10 to the 9th power ions/sq cm/sec. The calculated ionization rates and the capacity of the solar wind to remove ionized helium (He4) from the upper atmosphere during geomagnetic dipole reversals are sufficient to yield a secular equilibrium over geologic time scales. The upward transport of helium from the lower atmosphere under these conditions is found to be adequate to sustain the proposed loss rate.

  19. Midday reversal of equatorial ionospheric electric field

    Directory of Open Access Journals (Sweden)

    R. G. Rastogi

    1997-10-01

    Full Text Available A comparative study of the geomagnetic and ionospheric data at equatorial and low-latitude stations in India over the 20 year period 1956–1975 is described. The reversal of the electric field in the ionosphere over the magnetic equator during the midday hours indicated by the disappearance of the equatorial sporadic E region echoes on the ionograms is a rare phenomenon occurring on about 1% of time. Most of these events are associated with geomagnetically active periods. By comparing the simultaneous geomagnetic H field at Kodaikanal and at Alibag during the geomagnetic storms it is shown that ring current decreases are observed at both stations. However, an additional westward electric field is superimposed in the ionosphere during the main phase of the storm which can be strong enough to temporarily reverse the normally eastward electric field in the dayside ionosphere. It is suggested that these electric fields associated with the V×Bz electric fields originate at the magnetopause due to the interaction of the solar wind and the interplanetary magnetic field.

  20. Sugammadex: A Review of Neuromuscular Blockade Reversal.

    Science.gov (United States)

    Keating, Gillian M

    2016-07-01

    Sugammadex (Bridion(®)) is a modified γ-cyclodextrin that reverses the effect of the steroidal nondepolarizing neuromuscular blocking agents rocuronium and vecuronium. Intravenous sugammadex resulted in rapid, predictable recovery from moderate and deep neuromuscular blockade in patients undergoing surgery who received rocuronium or vecuronium. Recovery from moderate neuromuscular blockade was significantly faster with sugammadex 2 mg/kg than with neostigmine, and recovery from deep neuromuscular blockade was significantly faster with sugammadex 4 mg/kg than with neostigmine or spontaneous recovery. In addition, recovery from neuromuscular blockade was significantly faster when sugammadex 16 mg/kg was administered 3 min after rocuronium than when patients spontaneously recovered from succinylcholine. Sugammadex also demonstrated efficacy in various special patient populations, including patients with pulmonary disease, cardiac disease, hepatic dysfunction or myasthenia gravis and morbidly obese patients. Intravenous sugammadex was generally well tolerated. In conclusion, sugammadex is an important option for the rapid reversal of rocuronium- or vecuronium-induced neuromuscular blockade.

  1. Rocuronium blockade reversal with sugammadex vs. neostigmine

    DEFF Research Database (Denmark)

    Wu, Xinmin; Oerding, Helle; Liu, Jin

    2014-01-01

    BACKGROUND: This study compared efficacy and safety of the selective relaxant binding agent sugammadex (2 mg/kg) with neostigmine (50 μg/kg) for neuromuscular blockade (NMB) reversal in Chinese and Caucasian subjects. METHODS: This was a randomized, active-controlled, multicenter, safety-assessor......BACKGROUND: This study compared efficacy and safety of the selective relaxant binding agent sugammadex (2 mg/kg) with neostigmine (50 μg/kg) for neuromuscular blockade (NMB) reversal in Chinese and Caucasian subjects. METHODS: This was a randomized, active-controlled, multicenter, safety...... twitch reappearance, after last rocuronium dose, subjects received sugammadex 2 mg/kg or neostigmine 50 μg/kg plus atropine 10-20 μg/kg, according to randomization. Primary efficacy variable was time from sugammadex/neostigmine to recovery of the train-of-four (TOF) ratio to 0.9. RESULTS: Overall, 230...... Chinese subjects (sugammadex, n = 119, neostigmine, n = 111); and 59 Caucasian subjects (sugammadex, n = 29, neostigmine, n = 30) had evaluable data. Geometric mean (95% CI) time to recovery to TOF ratio 0.9 was 1.6 (1.5-1.7) min with sugammadex vs 9.1 (8.0-10.3) min with neostigmine in Chinese subjects...

  2. Dual kinetic curves in reversible electrochemical systems.

    Directory of Open Access Journals (Sweden)

    Michael J Hankins

    Full Text Available We introduce dual kinetic chronoamperometry, in which reciprocal relations are established between the kinetic curves of electrochemical reactions that start from symmetrical initial conditions. We have performed numerical and experimental studies in which the kinetic curves of the electron-transfer processes are analyzed for a reversible first order reaction. Experimental tests were done with the ferrocyanide/ferricyanide system in which the concentrations of each component could be measured separately using the platinum disk/gold ring electrode. It is shown that the proper ratio of the transient kinetic curves obtained from cathodic and anodic mass transfer limited regions give thermodynamic time invariances related to the reaction quotient of the bulk concentrations. Therefore, thermodynamic time invariances can be observed at any time using the dual kinetic curves for reversible reactions. The technique provides a unique possibility to extract the non-steady state trajectory starting from one initial condition based only on the equilibrium constant and the trajectory which starts from the symmetrical initial condition. The results could impact battery technology by predicting the concentrations and currents of the underlying non-steady state processes in a wide domain from thermodynamic principles and limited kinetic information.

  3. Time-reversal and Bayesian inversion

    Science.gov (United States)

    Debski, Wojciech

    2017-04-01

    Probabilistic inversion technique is superior to the classical optimization-based approach in all but one aspects. It requires quite exhaustive computations which prohibit its use in huge size inverse problems like global seismic tomography or waveform inversion to name a few. The advantages of the approach are, however, so appealing that there is an ongoing continuous afford to make the large inverse task as mentioned above manageable with the probabilistic inverse approach. One of the perspective possibility to achieve this goal relays on exploring the internal symmetry of the seismological modeling problems in hand - a time reversal and reciprocity invariance. This two basic properties of the elastic wave equation when incorporating into the probabilistic inversion schemata open a new horizons for Bayesian inversion. In this presentation we discuss the time reversal symmetry property, its mathematical aspects and propose how to combine it with the probabilistic inverse theory into a compact, fast inversion algorithm. We illustrate the proposed idea with the newly developed location algorithm TRMLOC and discuss its efficiency when applied to mining induced seismic data.

  4. Reverse Logistics Systems: Persepsi dan Harapan Konsumen

    Directory of Open Access Journals (Sweden)

    Farida Pulansari

    2016-12-01

    Full Text Available Complaint is a signal that indicates important information directly by customers. Complaint will give valuable information to company to plan recovery strategies to maintain customer satisfaction and loyalty. Hence, Electronic Waste (E-waste becomes a hot issue internationally, domestically and locally. There are many kind of regulations, strategy, methods or approach to minimize of E-waste. The goal of this research is design of House of Reverse Logistics (HRL to understanding the customer needs and wants for Reverse Logistics (RL implementation. This research adopted Quality Function Deployment (QFD method to construct the HRL. Differences among them are determination of the customer needs and wants. HRL insert five perspectives i.e. Input, Structure, Process, Output and Social & Organization. In other hand, QFD only inserts consumer perspective. The results showed the highest factors of consumer dissatisfaction comes from: 20% of third-party services mechanism, 10% from collaboration RL system (collection centers, recycling centers, disposal center ,10% comes the standardization of servicing system and 60% of others

  5. Magnetization reversal in ultrashort magnetic field pulses

    International Nuclear Information System (INIS)

    Bauer, M.; Lopusnik, R.; Fassbender, J.; Hillebrands, B.

    2000-01-01

    We report the switching properties of a thin magnetic film subject to an ultrashort, laterally localized magnetic field pulse, obtained by numerical investigations. The magnetization distribution in the film is calculated on a grid assuming Stoner-like coherent rotation within the grid square size. Perpendicularly and in-plane magnetized films exhibit a magnetization reversal due to a 4 ps magnetic field pulse. Outside the central region the pulse duration is short compared to the precession period. In this area the evolution of the magnetization during the field pulse does not depend strongly on magnetic damping and/or pulse shape. However, the final magnetization distribution is affected by the magnetic damping. Although the pulse duration is short compared to the precession period, the time needed for the relaxation of the magnetization to the equilibrium state is rather large. The influence of the different magnetic anisotropy contributions and the magnetic damping parameter enters into the magnetization reversal process. Comparing the case of perpendicular anisotropy with different kinds of in-plane anisotropies, a principal difference is found due to the symmetry of the shape anisotropy with respect to the anisotropy in question

  6. Neutrino helicity reversal and fundamental symmetries

    International Nuclear Information System (INIS)

    Jentschura, U D; Wundt, B J

    2014-01-01

    A rather elusive helicity reversal occurs in a gedanken experiment in which a massive left-handed Dirac neutrino, traveling at a velocity u < c, is overtaken on a highway by a speeding vehicle (traveling at velocity v with u < v < c). Namely, after passing the neutrino, looking back, one would see a right-handed neutrino (which has never been observed in nature). The Lorentz-invariant mass of the right-handed neutrino is still the same as before the passing. The gedanken experiment thus implies the existence of right-handed, light neutrinos, which are not completely sterile. Furthermore, overtaking a bunch of massive right-handed Dirac neutrinos leads to gradual de-sterilization. We discuss the helicity reversal and the concomitant sterilization and de-sterilization mechanisms by way of an illustrative example calculation, with a special emphasis on massive Dirac and Majorana neutrinos. We contrast the formalism with a modified Dirac neutrino described by a Dirac equation with a pseudoscalar mass term proportional to the fifth current. (paper)

  7. Elastic least-squares reverse time migration

    KAUST Repository

    Feng, Zongcai

    2017-03-08

    We use elastic least-squares reverse time migration (LSRTM) to invert for the reflectivity images of P- and S-wave impedances. Elastic LSRTMsolves the linearized elastic-wave equations for forward modeling and the adjoint equations for backpropagating the residual wavefield at each iteration. Numerical tests on synthetic data and field data reveal the advantages of elastic LSRTM over elastic reverse time migration (RTM) and acoustic LSRTM. For our examples, the elastic LSRTM images have better resolution and amplitude balancing, fewer artifacts, and less crosstalk compared with the elastic RTM images. The images are also better focused and have better reflector continuity for steeply dipping events compared to the acoustic LSRTM images. Similar to conventional leastsquares migration, elastic LSRTM also requires an accurate estimation of the P- and S-wave migration velocity models. However, the problem remains that, when there are moderate errors in the velocity model and strong multiples, LSRTMwill produce migration noise stronger than that seen in the RTM images.

  8. Midday reversal of equatorial ionospheric electric field

    Directory of Open Access Journals (Sweden)

    R. G. Rastogi

    Full Text Available A comparative study of the geomagnetic and ionospheric data at equatorial and low-latitude stations in India over the 20 year period 1956–1975 is described. The reversal of the electric field in the ionosphere over the magnetic equator during the midday hours indicated by the disappearance of the equatorial sporadic E region echoes on the ionograms is a rare phenomenon occurring on about 1% of time. Most of these events are associated with geomagnetically active periods. By comparing the simultaneous geomagnetic H field at Kodaikanal and at Alibag during the geomagnetic storms it is shown that ring current decreases are observed at both stations. However, an additional westward electric field is superimposed in the ionosphere during the main phase of the storm which can be strong enough to temporarily reverse the normally eastward electric field in the dayside ionosphere. It is suggested that these electric fields associated with the V×Bz electric fields originate at the magnetopause due to the interaction of the solar wind and the interplanetary magnetic field.

  9. Hybrid supercapacitors for reversible control of magnetism.

    Science.gov (United States)

    Molinari, Alan; Leufke, Philipp M; Reitz, Christian; Dasgupta, Subho; Witte, Ralf; Kruk, Robert; Hahn, Horst

    2017-05-10

    Electric field tuning of magnetism is one of the most intensely pursued research topics of recent times aiming at the development of new-generation low-power spintronics and microelectronics. However, a reversible magnetoelectric effect with an on/off ratio suitable for easy and precise device operation is yet to be achieved. Here we propose a novel route to robustly tune magnetism via the charging/discharging processes of hybrid supercapacitors, which involve electrostatic (electric-double-layer capacitance) and electrochemical (pseudocapacitance) doping. We use both charging mechanisms-occurring at the La 0.74 Sr 0.26 MnO 3 /ionic liquid interface to control the balance between ferromagnetic and non-ferromagnetic phases of La 1-x Sr x MnO 3 to an unprecedented extent. A magnetic modulation of up to ≈33% is reached above room temperature when applying an external potential of only about 2.0 V. Our case study intends to draw attention to new, reversible physico-chemical phenomena in the rather unexplored area of magnetoelectric supercapacitors.

  10. Elastic least-squares reverse time migration

    KAUST Repository

    Feng, Zongcai; Schuster, Gerard T.

    2017-01-01

    We use elastic least-squares reverse time migration (LSRTM) to invert for the reflectivity images of P- and S-wave impedances. Elastic LSRTMsolves the linearized elastic-wave equations for forward modeling and the adjoint equations for backpropagating the residual wavefield at each iteration. Numerical tests on synthetic data and field data reveal the advantages of elastic LSRTM over elastic reverse time migration (RTM) and acoustic LSRTM. For our examples, the elastic LSRTM images have better resolution and amplitude balancing, fewer artifacts, and less crosstalk compared with the elastic RTM images. The images are also better focused and have better reflector continuity for steeply dipping events compared to the acoustic LSRTM images. Similar to conventional leastsquares migration, elastic LSRTM also requires an accurate estimation of the P- and S-wave migration velocity models. However, the problem remains that, when there are moderate errors in the velocity model and strong multiples, LSRTMwill produce migration noise stronger than that seen in the RTM images.

  11. Parameter dependence of resonant spin torque magnetization reversal

    International Nuclear Information System (INIS)

    Fricke, L.; Serrano-Guisan, S.; Schumacher, H.W.

    2012-01-01

    We numerically study ultra fast resonant spin torque (ST) magnetization reversal in magnetic tunneling junctions (MTJ) driven by current pulses having a direct current (DC) and a resonant alternating current (AC) component. The precessional ST dynamics of the single domain MTJ free layer cell are modeled in the macro spin approximation. The energy efficiency, reversal time, and reversal reliability are investigated under variation of pulse parameters like direct and AC current amplitude, AC frequency and AC phase. We find a range of AC and direct current amplitudes where robust resonant ST reversal is obtained with faster switching time and reduced energy consumption per pulse compared to purely direct current ST reversal. However, for a certain range of AC and direct current amplitudes a strong dependence of the reversal properties on AC frequency and phase is found. Such regions of unreliable reversal must be avoided for ST memory applications.

  12. Parameter dependence of resonant spin torque magnetization reversal

    Science.gov (United States)

    Fricke, L.; Serrano-Guisan, S.; Schumacher, H. W.

    2012-04-01

    We numerically study ultra fast resonant spin torque (ST) magnetization reversal in magnetic tunneling junctions (MTJ) driven by current pulses having a direct current (DC) and a resonant alternating current (AC) component. The precessional ST dynamics of the single domain MTJ free layer cell are modeled in the macro spin approximation. The energy efficiency, reversal time, and reversal reliability are investigated under variation of pulse parameters like direct and AC current amplitude, AC frequency and AC phase. We find a range of AC and direct current amplitudes where robust resonant ST reversal is obtained with faster switching time and reduced energy consumption per pulse compared to purely direct current ST reversal. However, for a certain range of AC and direct current amplitudes a strong dependence of the reversal properties on AC frequency and phase is found. Such regions of unreliable reversal must be avoided for ST memory applications.

  13. Revenue in reverse? An examination of reverse supply chain enabled revenue streams

    DEFF Research Database (Denmark)

    Larsen, Samuel; Jacobsen, Peter

    2016-01-01

    When original equipment manufacturers (OEMs) examine whether to implement a reverse supply chain (RSC) for their products, oftentimes the motive is cost savings or regulatory compliance. However, a frequently overlooked but equally important benefit is the possibility for creating new revenue...

  14. Periodic feedwater reversal and air sparging as antifouling strategies in reverse electrodialysis

    NARCIS (Netherlands)

    Vermaas, D.A.; Kunteng, D.; Veerman, J.; Saakes, M.; Nijmeijer, K.

    2014-01-01

    Renewable energy can be generated using natural streams of seawater and river water in reverse electrodialysis (RED). The potential for electricity production of this technology is huge, but fouling of the membranes and the membrane stack reduces the potential for large scale applications. This

  15. Mass transfer with complex reversible chemical reactions—I. Single reversible chemical reaction

    NARCIS (Netherlands)

    Versteeg, G.F.; Kuipers, J.A.M.; Beckum, F.P.H. van; Swaaij, W.P.M. van

    1989-01-01

    An improved numerical technique was used in order to develop an absorption model with which it is possible to calculate rapidly absorption rates for the phenomenon of mass transfer accompanied by a complex reversible chemical reaction. This model can be applied for the calculation of the mass

  16. Mass transfer with complex reversible chemical reactions—II. parallel reversible chemical reactions

    NARCIS (Netherlands)

    Versteeg, G.F.; Kuipers, J.A.M.; Beckum, F.P.H. van; Swaaij, W.P.M. van

    1990-01-01

    An absorption model has been developed which can be used to calculate rapidly absorption rates for the phenomenon mass transfer accompanied by multiple complex parallel reversible chemical reactions. This model can be applied for the calculation of the mass transfer rates, enhancement factors and

  17. Mass transfer with complex reversible chemical reactions. II: Parallel reversible chemical reactions

    NARCIS (Netherlands)

    Versteeg, Geert; van Beckum, F.P.H.; Kuipers, J.A.M.; van Swaaij, Willibrordus Petrus Maria

    1990-01-01

    An absorption model has been developed which can be used to calculate rapidly absorption rates for the phenomenon mass transfer accompanied by multiple complex parallel reversible chemical reactions. This model can be applied for the calculation of the mass transfer rates, enhancement factors and

  18. Mass transfer with complex reversible chemical reactions. II: parallel reversible chemical reactions

    NARCIS (Netherlands)

    Versteeg, G.F.; Kuipers, J.A.M.; Beckum, van F.P.H.; van Swaaij, W.P.M.

    1990-01-01

    An absorption model has been developed which can be used to calculate rapidly absorption rates for the phenomenon mass transfer accompanied by multiple complex parallel reversible chemical reactions. This model can be applied for the calculation of the mass transfer rates, enhancement factors and

  19. Profits in reverse? An examination of the decisive factors for reverse supply chain profitability

    DEFF Research Database (Denmark)

    Larsen, Samuel; Jacobsen, Peter

    2015-01-01

    Although the concept of the reverse supply chain (RSC) is not unknown in industry, an inhibitor for its successful use is low (or no) profitability. A research challenge is investigating ways to establish the RSC as a profit-creating center in the organization. This paper contributes...

  20. Batteryless photovoltaic reverse-osmosis desalination system

    Energy Technology Data Exchange (ETDEWEB)

    Thomson, M.; Miranda, M.; Gwillim, J.; Rowbottom, A.; Draisey, I.

    2001-07-01

    The aim of this project was to design an efficient cost-effective batteryless photovoltaic-powered seawater reverse-osmosis desalination system, to deliver in the order of 3 m{sup 3} of fresh drinking water per day. The desalination of seawater to produce fresh drinking water is extremely valuable on islands and in coastal regions wherever natural freshwater is scarce. Existing small-scale desalination equipment, suitable for areas of medium and low population density, often requires a copious and constant supply of energy, either electricity or diesel. If supply of these fuels is expensive or insecure, but the area has a good solar resource, the use of photovoltaic power is an attractive option. Existing demonstrations of photovoltaic-powered desalination generally employ lead-acid batteries, which allow the equipment to operate at a constant flow, but are notoriously problematic in practice. The system developed in this project runs at variable flow, enabling it to make efficient use of the naturally varying solar resource, without need of batteries. In a sense, the freshwater tank is providing the energy storage. In this project, we have reviewed the merits of a wide variety of reverse-osmosis system configurations and component options. We have completed extensive in-house testing and characterisation of major hardware components and used the results to construct detailed software models. Using these, we have designed a system that meets the above project aim, and we have predicted its performance in detail. Our designs show that a system costing 23,055 pounds stirling will produce 1424 m{sup 3} of fresh drinking water annually - an average of just over 3.9 m{sup 3}/day. The system has no fuel costs and no batteries. The overall cost of water, including full maintenance, is 2.00 pounds stirling per m{sup 3}. The energy consumption (photovoltaic-electricity) is typically between 3.2 and 3.7 kWh/m{sup 3} depending on the solar irradiance and feed water

  1. Tilting mode in field-reversed configurations

    International Nuclear Information System (INIS)

    Schwarzmeier, J.L.; Barnes, D.C.; Lewis, H.R.; Seyler, C.E.; Shestakov, A.I.

    1982-01-01

    Field Reversed Configurations (FRCs) experimentally have exhibited remarkable stability on the magnetohydrodynamic (MHD) timescale, despite numerous MHD calculations showing FRCs to be unstable. It is easy to believe that local modes are stabilized by finite Larmor radius (FLR) effects, but more puzzling is the apparent stability of FRCs against global modes, where one would expect FLR effects to be less important. In this paper we study the tilting mode, which MHD has shown to be a rapidly growing global mode. The tilting mode in FRCs is driven by the pressure gradient, and magnetic compression and field line bending are the stabilizing forces. A schematic of the evolution of the tilting mode is shown. The tilting mode is considered dangerous, because it would lead to rapid tearing across the separatrix. Unlike spheromaks, the tilting mode in FRCs has a separatrix that is fixed in space, so that the mode is strictly internal

  2. Compact reversed-field pinch reactors (CRFPR)

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Miller, R.L.; Bathke, C.G.; Hagenson, R.L.; Copenhaver, C.; Werley, K.A.

    1986-01-01

    The unique confinement properties of the Reversed-Field Pinch (RFP) are exploited to examine physics and technical issues related to a compact, high-power-density fusion reactor. This resistive-coil, steady-state, toroidal device would use a dual-media power cycle driven by a fusion power core (FPC, i.e., plasma chamber, first wall, blanket, shield, and coils) with a power density and mass approaching values characteristic of pressurized-water fission rectors. A 1000-MWe(net) base case is selected from a comprehensive trade-off study to examine technological issues related to operating a high-power-density FPC. After describing the main physics and technology issues for this base-case reactor, directions for future study are suggested

  3. Reverse engineering of inductive fault current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Pina, J M; Neves, M Ventim; Rodrigues, A L [Centre of Technology and Systems Faculdade de Ciencias e Tecnologia, Nova University of Lisbon Monte de Caparica, 2829-516 Caparica (Portugal); Suarez, P; Alvarez, A, E-mail: jmmp@fct.unl.p [' Benito Mahedero' Group of Electrical Applications of Superconductors Escuela de IngenierIas Industrials, University of Extremadura Avenida de Elvas s/n, 06006 Badajoz (Spain)

    2010-06-01

    The inductive fault current limiter is less compact and harder to scale to high voltage networks than the resistive one. Nevertheless, its simple construction and mechanical robustness make it attractive in low voltage grids. Thus, it might be an enabling technology for the advent of microgrids, low voltage networks with dispersed generation, controllable loads and energy storage. A new methodology for reverse engineering of inductive fault current limiters based on the independent analysis of iron cores and HTS cylinders is presented in this paper. Their electromagnetic characteristics are used to predict the devices' hysteresis loops and consequently their dynamic behavior. Previous models based on the separate analysis of the limiters' components were already derived, e.g. in transformer like equivalent models. Nevertheless, the assumptions usually made may limit these models' application, as shown in the paper. The proposed methodology obviates these limitations. Results are validated through simulations.

  4. Theory of field-reversed configurations

    International Nuclear Information System (INIS)

    Steinhauer, L.C.

    1993-01-01

    This report summarizes results from the theoretical program on field reversed configurations (FRC) at STI Optronics. The program, which has spanned the last 13 years, has included analytical as well as computational components. It has led to published papers on every major topic of FRC theory. The report is outlined to summarize results from each of these topic areas: formation, equilibrium, stability, and confinement. Also briefly described are Steinhauer's activities as Compact Toroid Theory Listening Post. Appendix A is a brief listing of the major advances achieved in this program. Attached at the back of this report is a collection of technical papers in archival journals that resulted from work in this program. The discussion within each subsection is given chronologically in order to give a historical sense of the evolution of understanding of FRC physics

  5. LASL toroidal reversed-field pinch programme

    International Nuclear Information System (INIS)

    Baker, D.A.; Buchenauer, C.J.; Burkhardt, L.C.

    1979-01-01

    The determination of the absolute energy loss due to radiation from impurities in the LASL toroidal reversed-field pinch experiment ZT-S is reported. The measurements show that over half the energy loss is accounted for by this mechanism. Thomson-scattering electron density measurements indicate only a gradual increase in temperature as the filling pressure is reduced, indicating an increased energy loss at lower pressures. Cylindrical and toroidal simulations of the experiment indicate either that a highly radiative pinch boundary or anomalous transport is needed to match the experimental results. New effects on the equilibrium due to plasma flows induced by the toroidal geometry are predicted by the toroidal simulations. The preliminary results on the low-temperature discharge cleaning of the ZT-S torus are reported. A description of the upgrade of the ZT-S experiment and the objectives, construction and theoretical predictions for the new ZT-40 experiment are given. (author)

  6. Rotational instabilities in field reversed configurations

    International Nuclear Information System (INIS)

    Santiago, M.A.M.; Tsui, K.H.; Ponciano, B.M.B.; Sakanaka, P.H.

    1988-01-01

    The rotational instability (n = 2 toroidal mode) in field reversed configurations (FRC) using the ideal MHD equations in cylindrical geometry is studied. These equations are solved using a realistic densite profile, and the influence of some plasma parameters on the growth rate is analysed. The model shows good qualitative results. The growth rate increases rapidly as rotational frequency goes up and the mode m = 2 dominates over the m = 1 mode. With the variation of the density profile, it is observed that the growth rate decreases as the density dip at the center fills up. Calculated value ranges from 1/2 to 1/7 of the rotational frequency Ω whereas the measured value is around Ω/50. The developed analysis is valid for larger machines. The influence of the plasma resistivity on the mode stabilization is also analysed. The resistivity, which is the fundamental factor in the formation of compact torus, tends to decrease the growth rate. (author) [pt

  7. Reverse engineering of inductive fault current limiters

    International Nuclear Information System (INIS)

    Pina, J M; Neves, M Ventim; Rodrigues, A L; Suarez, P; Alvarez, A

    2010-01-01

    The inductive fault current limiter is less compact and harder to scale to high voltage networks than the resistive one. Nevertheless, its simple construction and mechanical robustness make it attractive in low voltage grids. Thus, it might be an enabling technology for the advent of microgrids, low voltage networks with dispersed generation, controllable loads and energy storage. A new methodology for reverse engineering of inductive fault current limiters based on the independent analysis of iron cores and HTS cylinders is presented in this paper. Their electromagnetic characteristics are used to predict the devices' hysteresis loops and consequently their dynamic behavior. Previous models based on the separate analysis of the limiters' components were already derived, e.g. in transformer like equivalent models. Nevertheless, the assumptions usually made may limit these models' application, as shown in the paper. The proposed methodology obviates these limitations. Results are validated through simulations.

  8. Particle transport in field-reversed configurations

    Energy Technology Data Exchange (ETDEWEB)

    Tuszewski, M.; Linford, R.K.

    1982-05-01

    Particle transport in field-reversed configurations is investigated using a one-dimensional, nondecaying, magnetic field structure. The radial profiles are constrained to satisfy an average ..beta.. condition from two-dimensional equilibrium and a boundary condition at the separatrix to model the balance between closed and open-field-line transport. When applied to the FRX-B experimental data and to the projected performance of the FRX-C device, this model suggests that the particle confinement times obtained with anomalous lower-hybrid-drift transport are in good agreement with the available numerical and experimental data. Larger values of confinement times can be achieved by increasing the ratio of the separatrix radius to the conducting wall radius. Even larger increases in lifetimes might be obtained by improving the open-field-line confinement.

  9. Particle transport in field-reversed configurations

    International Nuclear Information System (INIS)

    Tuszewski, M.; Linford, R.K.

    1982-01-01

    Particle transport in field-reversed configurations is investigated using a one-dimensional, nondecaying, magnetic field structure. The radial profiles are constrained to satisfy an average β condition from two-dimensional equilibrium and a boundary condition at the separatrix to model the balance between closed and open-field-line transport. When applied to the FRX-B experimental data and to the projected performance of the FRX-C device, this model suggests that the particle confinement times obtained with anomalous lower-hybrid-drift transport are in good agreement with the available numerical and experimental data. Larger values of confinement times can be achieved by increasing the ratio of the separatrix radius to the conducting wall radius. Even larger increases in lifetimes might be obtained by improving the open-field-line confinement

  10. Obesity-related hypogonadism: a reversible condition.

    Science.gov (United States)

    Zouras, Stamatios; Stephens, Jeffrey W; Price, David

    2017-06-23

    Obesity is associated with hypogonadism. While this association is widely accepted, the underlying mechanisms remain unclear. Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. We present the case of a morbidly obese man aged 30 years with hypogonadotrophic hypogonadism that underwent a Roux-en-Y gastric bypass operation. Following the surgical treatment of his obesity, the testosterone level returned to normal with improvements in hypogonadal symptoms, which allowed discontinuation of exogenous testosterone therapy. This case report demonstrates reversal of hypogonadism following weight loss with restoration of gonadal function. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  11. Reversal thyristor-relay direct current commutator

    International Nuclear Information System (INIS)

    Ivanenko, A.I.

    1982-01-01

    A thyristor-relay commutator used for alteration of the leading magnetic field direction in experiments with polarized neutrons is described. The commutator flowsheet is presented. Thyristors, connected so as to allow the relay trigger operation mode, are used as controllable electronic relay. Two connected in series coils with the total inductance of the order of 0.28 H serve as the electronic relay load. The arc-free current commutation is effected at the moment of the minimal current across the load terminals, which allows to easily reverse the current up to 10 A at a volatage, v <= 150 V. The experience gained within a year of operation has shown that the commutator meets the requirements of reliability and tuning

  12. LASL toroidal reversed-field pinch program

    International Nuclear Information System (INIS)

    Baker, D.A.; Buchenauer, C.J.; Burkhardt, L.C.

    1978-01-01

    The determination of the absolute energy loss due to radiation from impurities in the LASL toroidal reversed-field pinch experiment ZT-S is reported. The measurements show over half of the energy loss is accounted for by this mechanism. Thomson scattering electron density measurements indicate only a gradual increase in temperature as the filling pressure is reduced indicating an increased energy loss at lower pressures. Cylindrical and toroidal simulations of the experiment indicate either that a highly radiative pinch boundary or anomalous transport are needed to match the experimental results. New effects on the equilibrium due to plasma flows induced by the toroidal geometry are predicted by the toroidal simulations. The preliminary results on the low temperature discharge cleaning of the ZT-S torus are reported. A description of the upgrade of the ZT-S experiment and the objectives, construction and theoretical predictions for the new ZT-40 experiment are given

  13. Bio-inspired reversible underwater adhesive.

    Science.gov (United States)

    Zhao, Yanhua; Wu, Yang; Wang, Liang; Zhang, Manman; Chen, Xuan; Liu, Minjie; Fan, Jun; Liu, Junqiu; Zhou, Feng; Wang, Zuankai

    2017-12-20

    The design of smart surfaces with switchable adhesive properties in a wet environment has remained a challenge in adhesion science and materials engineering. Despite intense demands in various industrial applications and exciting progress in mimicking the remarkable wet adhesion through the delicate control of catechol chemistry, polyelectrolyte complex, and supramolecular architectures, the full recapitulation of nature's dynamic function is limited. Here, we show a facile approach to synthesize bioinspired adhesive, which entails the reversible, tunable, and fast regulation of the wet adhesion on diverse surfaces. The smart wet adhesive takes advantage of the host-guest molecular interaction and the adhesive nature of catechol chemistry, as well as the responsive polymer, allowing for screening and activation of the interfacial interaction simply by a local temperature trigger in an on-demand manner. Our work opens up an avenue for the rational design of bioinspired adhesives with performances even beyond nature.

  14. An interlacing theorem for reversible Markov chains

    International Nuclear Information System (INIS)

    Grone, Robert; Salamon, Peter; Hoffmann, Karl Heinz

    2008-01-01

    Reversible Markov chains are an indispensable tool in the modeling of a vast class of physical, chemical, biological and statistical problems. Examples include the master equation descriptions of relaxing physical systems, stochastic optimization algorithms such as simulated annealing, chemical dynamics of protein folding and Markov chain Monte Carlo statistical estimation. Very often the large size of the state spaces requires the coarse graining or lumping of microstates into fewer mesoscopic states, and a question of utmost importance for the validity of the physical model is how the eigenvalues of the corresponding stochastic matrix change under this operation. In this paper we prove an interlacing theorem which gives explicit bounds on the eigenvalues of the lumped stochastic matrix. (fast track communication)

  15. An interlacing theorem for reversible Markov chains

    Energy Technology Data Exchange (ETDEWEB)

    Grone, Robert; Salamon, Peter [Department of Mathematics and Statistics, San Diego State University, San Diego, CA 92182-7720 (United States); Hoffmann, Karl Heinz [Institut fuer Physik, Technische Universitaet Chemnitz, D-09107 Chemnitz (Germany)

    2008-05-30

    Reversible Markov chains are an indispensable tool in the modeling of a vast class of physical, chemical, biological and statistical problems. Examples include the master equation descriptions of relaxing physical systems, stochastic optimization algorithms such as simulated annealing, chemical dynamics of protein folding and Markov chain Monte Carlo statistical estimation. Very often the large size of the state spaces requires the coarse graining or lumping of microstates into fewer mesoscopic states, and a question of utmost importance for the validity of the physical model is how the eigenvalues of the corresponding stochastic matrix change under this operation. In this paper we prove an interlacing theorem which gives explicit bounds on the eigenvalues of the lumped stochastic matrix. (fast track communication)

  16. Observation uncertainty in reversible Markov chains.

    Science.gov (United States)

    Metzner, Philipp; Weber, Marcus; Schütte, Christof

    2010-09-01

    In many applications one is interested in finding a simplified model which captures the essential dynamical behavior of a real life process. If the essential dynamics can be assumed to be (approximately) memoryless then a reasonable choice for a model is a Markov model whose parameters are estimated by means of Bayesian inference from an observed time series. We propose an efficient Monte Carlo Markov chain framework to assess the uncertainty of the Markov model and related observables. The derived Gibbs sampler allows for sampling distributions of transition matrices subject to reversibility and/or sparsity constraints. The performance of the suggested sampling scheme is demonstrated and discussed for a variety of model examples. The uncertainty analysis of functions of the Markov model under investigation is discussed in application to the identification of conformations of the trialanine molecule via Robust Perron Cluster Analysis (PCCA+) .

  17. Reverse hypothesis machine learning a practitioner's perspective

    CERN Document Server

    Kulkarni, Parag

    2017-01-01

    This book introduces a paradigm of reverse hypothesis machines (RHM), focusing on knowledge innovation and machine learning. Knowledge- acquisition -based learning is constrained by large volumes of data and is time consuming. Hence Knowledge innovation based learning is the need of time. Since under-learning results in cognitive inabilities and over-learning compromises freedom, there is need for optimal machine learning. All existing learning techniques rely on mapping input and output and establishing mathematical relationships between them. Though methods change the paradigm remains the same—the forward hypothesis machine paradigm, which tries to minimize uncertainty. The RHM, on the other hand, makes use of uncertainty for creative learning. The approach uses limited data to help identify new and surprising solutions. It focuses on improving learnability, unlike traditional approaches, which focus on accuracy. The book is useful as a reference book for machine learning researchers and professionals as ...

  18. Method for conducting underground reverse combustion

    Energy Technology Data Exchange (ETDEWEB)

    Craig, Jr, F F; Neil, J D; Parrish, D R; Scott, P H

    1965-05-25

    This is a procedure for conducting a reverse-combustion operation in a formation penetrated by an injection well and a producing well which have objectionable fluids between them. The procedure consists of shutting-in the injection well and injecting a sufficient quantity of oxygen-containing gas into the deposit by the producing well to force these undesirable fluids away from the vicinity of the wells. Next, the deposit is ignited in the vicinity of the producing well. In this manner, the producing well is opened to production. At substantially the same time, an oxygen-containing gas is injected into the deposit through the injection well, so that the resulting combustion-front travels countercurrently to the path of the gas. (4 claims)

  19. Grain boundary cavitation under reversed constant stress

    International Nuclear Information System (INIS)

    Hales, R.

    1978-06-01

    The growth of grain boundary cavities by diffusion processes has been examined for cyclic stresses. It is found that the time required to grow a void by a predetermined amount (tsub(t)) is always longer than the time required to shrink the same defect to its original size (tsub(c)) under reversed stress. The ratio tsub(c)/tsub(t) is a function of the magnitude of the applied stress and tensile hold time. Similar calculations have been performed for gas filled bubbles. Similar results to those for voids are found at long hold times, but a significantly different ratio of tsub(c)/tsub(t) is obtained at short times. (author)

  20. Reversible exciplex formation followed charge separation.

    Science.gov (United States)

    Petrova, M V; Burshtein, A I

    2008-12-25

    The reversible exciplex formation followed by its decomposition into an ion pair is considered, taking into account the subsequent geminate and bulk ion recombination to the triplet and singlet products (in excited and ground states). The integral kinetic equations are derived for all state populations, assuming that the spin conversion is performed by the simplest incoherent (rate) mechanism. When the forward and backward electron transfer is in contact as well as all dissociation/association reactions of heavy particles, the kernels of integral equations are specified and expressed through numerous reaction constants and characteristics of encounter diffusion. The solutions of these equations are used to specify the quantum yields of the excited state and exciplex fluorescence induced by pulse or stationary pumping. In the former case, the yields of the free ions and triplet products are also found, while in the latter case their stationary concentrations are obtained.

  1. Metaheuristic analysis in reverse logistics of waste

    Energy Technology Data Exchange (ETDEWEB)

    Serrano Elena, A.

    2016-07-01

    This paper focuses in the use of search metaheuristic techniques on a dynamic and deterministic model to analyze and solve cost optimization problems and location in reverse logistics, within the field of municipal waste management of Málaga (Spain). In this work we have selected two metaheuristic techniques having relevance in present research, to test the validity of the proposed approach: an important technique for its international presence as is the Genetic Algorithm (GA) and another interesting technique that works with swarm intelligence as is the Particles Swarm Optimization (PSO). These metaheuristic techniques will be used to solve cost optimization problems and location of MSW recovery facilities (transfer centers and treatment plants). (Author)

  2. A Case Report of Reversible Dilated Cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Abhishek Singhai

    2014-01-01

    Full Text Available Dilated cardiomyopathy (DCM is mostly an idiopathic disease with a progressive and irreversible course. It carries poor prognosis and outcome. Rarely, a reversible metabolic etiology that is amenable to specific therapy is identified. Alteration in thyroid status can lead to changes in systolic and diastolic function of left ventricle. Heart is sensitive to thyroid hormone changes, and cardiac disorders are commonly associated with both hyper and hypothyroidism. Diastolic dysfunction is the most common abnormality reported in hypothyroidism. In systolic function, prolonged systolic time interval or normal cardiac function has been reported by most workers. DCM is a rare presentation of hypothyroidism. Here, we report a case of 40-year-old female diagnosed with DCM due to hypothyroidism

  3. Reverse Taylor Tests on Ultrafine Grained Copper

    International Nuclear Information System (INIS)

    Mishra, A.; Meyers, M. A.; Martin, M.; Thadhani, N. N.; Gregori, F.; Asaro, R. J.

    2006-01-01

    Reverse Taylor impact tests have been carried out on ultrafine grained copper processed by Equal Channel Angular Pressing (ECAP). Tests were conducted on an as-received OFHC Cu rod and specimens that had undergone sequential ECAP passes (2 and 8). The average grain size ranged from 30 μm for the initial sample to less than 0.5 μm for the 8-pass samples. The dynamic deformation states of the samples, captured by high speed digital photography were compared with computer simulations run in AUTODYN-2D using the Johnson-Cook constitutive equation with constants obtained from stress-strain data and by fitting to an experimentally measured free surface velocity trace. The constitutive response of copper of varying grain sizes was obtained through quasistatic and dynamic mechanical tests and incorporation into constitutive models

  4. Multiples least-squares reverse time migration

    KAUST Repository

    Zhang, Dongliang

    2013-01-01

    To enhance the image quality, we propose multiples least-squares reverse time migration (MLSRTM) that transforms each hydrophone into a virtual point source with a time history equal to that of the recorded data. Since each recorded trace is treated as a virtual source, knowledge of the source wavelet is not required. Numerical tests on synthetic data for the Sigsbee2B model and field data from Gulf of Mexico show that MLSRTM can improve the image quality by removing artifacts, balancing amplitudes, and suppressing crosstalk compared to standard migration of the free-surface multiples. The potential liability of this method is that multiples require several roundtrips between the reflector and the free surface, so that high frequencies in the multiples are attenuated compared to the primary reflections. This can lead to lower resolution in the migration image compared to that computed from primaries.

  5. Reversible Polarization Rotation in Epitaxial Ferroelectric Bilayers

    DEFF Research Database (Denmark)

    Liu, Guangqing; Zhang, Qi; Huang, Hsin-Hui

    2016-01-01

    Polarization rotation engineering is a promising path to giant dielectric and electromechanical responses in ferroelectric materials and devices. This work demonstrates robust and reversible in- to out-of-plane polarization rotation in ultrathin (nanoscale) epitaxial (001) tetragonal PbZr0.3Ti0.7O3...... large-scale polarization rotation switching (≈60 μC cm−2) and an effective d 33 response 500% (≈250 pm V−1) larger than the PZT-R layer alone. Furthermore, this enhancement is stable for more than 107 electrical switching cycles. These bilayers present a simple and highly controllable means to design...... and optimize rotational polar systems as an alternate to traditional composition-based approaches. The precise control of the subtle interface-driven interactions between the lattice and the external factors that control polarization opens a new door to enhanced—or completely new—functional properties....

  6. Reverse Universal Resolving Algorithm and inverse driving

    DEFF Research Database (Denmark)

    Pécseli, Thomas

    2012-01-01

    Inverse interpretation is a semantics based, non-standard interpretation of programs. Given a program and a value, an inverse interpreter finds all or one of the inputs, that would yield the given value as output with normal forward evaluation. The Reverse Universal Resolving Algorithm is a new...... variant of the Universal Resolving Algorithm for inverse interpretation. The new variant outperforms the original algorithm in several cases, e.g., when unpacking a list using inverse interpretation of a pack program. It uses inverse driving as its main technique, which has not been described in detail...... before. Inverse driving may find application with, e.g., supercompilation, thus suggesting a new kind of program inverter....

  7. Seismic tomography with the reversible jump algorithm

    Science.gov (United States)

    Bodin, Thomas; Sambridge, Malcolm

    2009-09-01

    The reversible jump algorithm is a statistical method for Bayesian inference with a variable number of unknowns. Here, we apply this method to the seismic tomography problem. The approach lets us consider the issue of model parametrization (i.e. the way of discretizing the velocity field) as part of the inversion process. The model is parametrized using Voronoi cells with mobile geometry and number. The size, position and shape of the cells defining the velocity model are directly determined by the data. The inverse problem is tackled within a Bayesian framework and explicit regularization of model parameters is not required. The mobile position and number of cells means that global damping procedures, controlled by an optimal regularization parameter, are avoided. Many velocity models with variable numbers of cells are generated via a transdimensional Markov chain and information is extracted from the ensemble as a whole. As an aid to interpretation we visualize the expected earth model that is obtained via Monte Carlo integration in a straightforward manner. The procedure is particularly adept at imaging rapid changes or discontinuities in wave speed. While each velocity model in the final ensemble consists of many discontinuities at cell boundaries, these are smoothed out in the averaged ensemble solution while those required by the data are reinforced. The ensemble of models can also be used to produce uncertainty estimates and experiments with synthetic data suggest that they represent actual uncertainty surprisingly well. We use the fast marching method in order to iteratively update the ray geometry and account for the non-linearity of the problem. The method is tested here with synthetic data in a 2-D application and compared with a subspace method that is a more standard matrix-based inversion scheme. Preliminary results illustrate the advantages of the reversible jump algorithm. A real data example is also shown where a tomographic image of Rayleigh wave

  8. Reversible Unfolding of Rhomboid Intramembrane Proteases.

    Science.gov (United States)

    Panigrahi, Rashmi; Arutyunova, Elena; Panwar, Pankaj; Gimpl, Katharina; Keller, Sandro; Lemieux, M Joanne

    2016-03-29

    Denaturant-induced unfolding of helical membrane proteins provides insights into their mechanism of folding and domain organization, which take place in the chemically heterogeneous, anisotropic environment of a lipid membrane. Rhomboid proteases are intramembrane proteases that play key roles in various diseases. Crystal structures have revealed a compact helical bundle with a buried active site, which requires conformational changes for the cleavage of transmembrane substrates. A dimeric form of the rhomboid protease has been shown to be important for activity. In this study, we examine the mechanism of refolding for two distinct rhomboids to gain insight into their secondary structure-activity relationships. Although helicity is largely abolished in the unfolded states of both proteins, unfolding is completely reversible for HiGlpG but only partially reversible for PsAarA. Refolding of both proteins results in reassociation of the dimer, with a 90% regain of catalytic activity for HiGlpG but only a 70% regain for PsAarA. For both proteins, a broad, gradual transition from the native, folded state to the denatured, partly unfolded state was revealed with the aid of circular dichroism spectroscopy as a function of denaturant concentration, thus arguing against a classical two-state model as found for many globular soluble proteins. Thermal denaturation has irreversible destabilizing effects on both proteins, yet reveals important functional details regarding substrate accessibility to the buried active site. This concerted biophysical and functional analysis demonstrates that HiGlpG, with a simple six-transmembrane-segment organization, is more robust than PsAarA, which has seven predicted transmembrane segments, thus rendering HiGlpG amenable to in vitro studies of membrane-protein folding. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  9. Posterior Reversible Encephalopathy Syndrome in Our Setup

    International Nuclear Information System (INIS)

    Ahmad, I.; Zubair, U. B.; Mumtaz, H.; Yousaf, M. A.; Muhammad, W. W.

    2013-01-01

    Objectives: To assess the clinical presentation and neuroimaging abnormalities in a series of patients diagnosed as posterior reversible encephalopathy syndrome at Military Hospital Rawalpindi. Study Design: Case series study. Place and Duration: Study was carried out at Military Hospital Rawalpindi form December 01st, 2011 to May 31st, 2012. Patients and Methods: Study included all the cases of the Posterior reversible encephalopathy syndrome (PRES) admitted in the wards and intensive care unit (ITC). Neuroimaging was done and all the studies were reviewed by independent neuroradiologist. Different clinical and laboratory variables were also studied and correlated with neuroimaging. Follow up ws done to look for the prognosis. Results: Of the seven patients labelled as PRES two were male and five were female. Two patients were over 50 years of age, out of them one was male and one was female. One patient had end stage renal disease (ESRD) secondary to diabetes mellitus (DM) and hypertension (HTN), one had eclampsia, one had pregnancy-induced hypertension (PIH) and one had just uncontrolled HTN. Peak spontaneous bacterial peritonitis (SBP) in 5 cases was 210 mm of Hg, four of which had seizures. Rest two had spontaneous bacterial peritonitis (SBP) of 160 out of which one developed seizures. Total out of 7, 5 experienced seizures and altered conscious state, rest two only had confusion. One patient had papilloedema. Follow up was done after 06 weeks, 02 patients died, 05 remained alive and symptoms of PRES had vanished. Conclusion: PRES is a neurological emergency, presents with a variety of symptoms and has a specific neuroimaging pattern. Early recognition and prompt treatment result in a good neurological outcome. (author)

  10. NERVE: New Enhanced Reverse Vaccinology Environment

    Directory of Open Access Journals (Sweden)

    Filippini Francesco

    2006-07-01

    Full Text Available Abstract Background Since a milestone work on Neisseria meningitidis B, Reverse Vaccinology has strongly enhanced the identification of vaccine candidates by replacing several experimental tasks using in silico prediction steps. These steps have allowed scientists to face the selection of antigens from the predicted proteome of pathogens, for which cell culture is difficult or impossible, saving time and money. However, this good example of bioinformatics-driven immunology can be further developed by improving in silico steps and implementing biologist-friendly tools. Results We introduce NERVE (New Enhanced Reverse Vaccinology Environment, an user-friendly software environment for the in silico identification of the best vaccine candidates from whole proteomes of bacterial pathogens. The software integrates multiple robust and well-known algorithms for protein analysis and comparison. Vaccine candidates are ranked and presented in a html table showing relevant information and links to corresponding primary data. Information concerning all proteins of the analyzed proteome is not deleted along selection steps but rather flows into an SQL database for further mining and analyses. Conclusion After learning from recent years' works in this field and analysing a large dataset, NERVE has been implemented and tuned as the first available tool able to rank a restricted pool (~8–9% of the whole proteome of vaccine candidates and to show high recall (~75–80% of known protective antigens. These vaccine candidates are required to be "safe" (taking into account autoimmunity risk and "easy" for further experimental, high-throughput screening (avoiding possibly not soluble antigens. NERVE is expected to help save time and money in vaccine design and is available as an additional file with this manuscript; updated versions will be available at http://www.bio.unipd.it/molbinfo.

  11. Laparoscopic tubal sterilization reversal and fertility outcomes

    Directory of Open Access Journals (Sweden)

    K Jayakrishnan

    2011-01-01

    Full Text Available Purpose: The purpose of the study was two-fold. Firstly it was to assess the suitability for tubal recanalization and factors predicting successful laparoscopic recanalization. Secondly, it was to analyze the fertility outcomes and factors affecting the pregnancy rate following laparoscopic tubal recanalization. Materials and Methods: A retrospective chart review of prospectively followed-up 29 women at a tertiary care center seeking tubal sterilization reversal between May 2005 and February 2010 were included. Results: In 14 (48.3% women unilateral tubes were suitable and in only 3 women (10.3% bilateral tubes were suitable. All cases with laparoscopic tubal sterilization were suitable, whereas all cases with fimbriectomy were unsuitable for recanalization. In 6 (20.7% cases salphingostomy was performed as an alternative procedure to tubal reanastomosis. The overall pregnancy rate was 58.8%. In cases with sterilization by Pomeroy′s method, 4 out of 10 (40% conceived, whereas for laparoscopic tubal ligation cases 6 out of 7 (85.7% conceived (P=0.32. None of the patients with final tubal length <5 cm conceived (P=0.03. Comparing the age at recanalization, in women ≤30 years, 71.4% conceived, as compared with 50% when age of women was more than 30 years (P=0.37. Conclusions: The important factors determining the success of recanalization are technique of sterilization and the remaining length of the tube after recanalization. The gynecologist must use an effective technique of sterilization to minimize the failure rates, but at the same time, which causes minimal trauma, and aim at preserving the length of the tube so that reversal is more likely to be successful, should the patient′s circumstances change.

  12. Simulative research on reverse current in magnetically insulated coaxial diode

    Directory of Open Access Journals (Sweden)

    Danni Zhu

    2017-10-01

    Full Text Available The reverse current tends to occur in the transition region of the guiding magnetic field in a magnetically insulated coaxial diode (MICD. Influence of the guiding magnetic field on characteristics of the MICD especially on the reverse current is studied by the particle-in-cell (PIC simulation in this paper. The reverse current is confirmed to be irrelevant with the guiding magnetic field strength. However, the reverse current is clarified quantitatively to depend on the electric and magnetic field distribution in the upstream of the cathode tip. As the MICD has been widely employed in microwave tubes, a simple approach to suppress the reverse current on the premise of little change of the original diode is valuable and thus proposed. The optimum matching point between the cathode and the magnetic field is selected in consideration of the entrance depth tolerance, the diode impedance discrepancy and the reverse current coefficient.

  13. Boiler feedwater treatment using reverse osmosis at Suncor OSG

    International Nuclear Information System (INIS)

    Brown, T.

    1997-01-01

    The installation of a new 1000 cu m/hr reverse osmosis water treatment system for boiler feedwater at a Suncor plant was discussed. The selection process began in 1993 when Suncor identified a need to increase its boiler feedwater capacity. The company reviewed many options available to increase the treated water capacity. These included: contracting the supply of treated water, adding additional capacity, replacing the entire plant, reverse osmosis, and demineralization. The eventual decision was to build a new 1000 cu m/hr reverse osmosis water treatment plant with the following key components: a Degremont Infilco Ultra Pulsator Clarifier and a Glegg Water Conditioning multimedia filter, Amberpack softeners and reverse osmosis arrays. The reverse osmosis plant was environmentally favourable over an equivalent demineralization plant. A technical comparison was provided between demineralization and reverse osmosis. The system has proven to be successful and economical in meeting the plants needs. 5 figs

  14. Modulation of hepatic stellate cells and reversibility of hepatic fibrosis

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Yu, E-mail: 1293363632@QQ.com [Faculty of Graduate Studies of Guangxi University of Chinese Medicine, Nanning 530001, Guangxi Zhuang Autonomous Region (China); Deng, Xin, E-mail: Hendly@163.com [Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, 10 East China Road, Nanning 530011, Guangxi Zhuang Autonomous Region (China); Liang, Jian, E-mail: lj99669@163.com [Guangxi University of Chinese Medicine, Nanning 530001, Guangxi Zhuang Autonomous Region (China)

    2017-03-15

    Hepatic fibrosis (HF) is the pathological component of a variety of chronic liver diseases. Hepatic stellate cells (HSC) are the main collagen-producing cells in the liver and their activation promotes HF. If HSC activation and proliferation can be inhibited, HF occurrence and development can theoretically be reduced and even reversed. Over the past ten years, a number of studies have addressed this process, and here we present a review of HSC modulation and HF reversal. - Highlights: • We present a review of the modulation of hepatic stellate cells (HSC) and reversibility of hepatic fibrosis (HF). • HSC are the foci of HF occurrence and development, HF could be prevented and treated by modulating HSC. • If HSC activation and proliferation can be inhibited, HF could theoretically be inhibited and even reversed. • Prevention or reversal of HSC activation, or promotion of HSC apoptosis, immune elimination, and senescence may prevent, inhibit or reverse HF.

  15. Transitional paleointensities from Kauai, Hawaii, and geomagnetic reversal models

    Science.gov (United States)

    Bogue, Scott W.; Coe, Robert S.

    1984-01-01

    Previously presented paleointensity results from an R-N transition zone in Kauai, Hawaii, show that field intensity dropped from 0. 431 Oe to 0. 101 Oe while the field remained within 30 degree of the reversed axial dipole direction. A recovery in intensity and the main directional change followed this presumably short period of low field strength. As the reversal neared completion, the field has an intensity of 0. 217 Oe while still 40 degree from the final direction. The relationship of paleointensity to field direction during the early part of the reversal thus differs from that toward the end, a feature that only some reversal models are consistent with. For example, a model in which a standing nondipole component persists through the dipole reversal predicts only symmetric intensity patterns. In contrast, zonal flooding models generate suitably complex field behavior if multiple flooding schemes operate during a single reversal or if the flooding process is itself asymmetric.

  16. Clean translation of an imperative reversible programming language

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock

    2011-01-01

    We describe the translation techniques used for the code generation in a compiler from the high-level reversible imperative programming language Janus to the low-level reversible assembly language PISA. Our translation is both semantics preserving (correct), in that target programs compute exactly...... the same functions as their source programs (cleanly, with no extraneous garbage output), and efficient, in that target programs conserve the complexities of source programs. In particular, target programs only require a constant amount of temporary garbage space. The given translation methods are generic......, and should be applicable to any (imperative) reversible source language described with reversible flowcharts and reversible updates. To our knowledge, this is the first compiler between reversible languages where the source and target languages were independently developed; the first exhibiting both...

  17. Monoamines stimulate sex reversal in the saddleback wrasse.

    Science.gov (United States)

    Larson, Earl T; Norris, David O; Gordon Grau, E; Summers, Cliff H

    2003-02-15

    Monoamine neurotransmitters (norepinephrine, dopamine, and serotonin) play an important role in reproduction and sexual behavior throughout the vertebrates. They are the first endogenous chemical signals in the regulation of the hypothalamo-pituitary-gonadal (HPG) axis. In teleosts with behavioral sex determination, much is known about behavioral cues that induce sex reversal. The cues are social, processed via the visual system and depend on the ratio of females to males in the population. The mechanisms by which these external behavioral cues are converted to an internal chemical regulatory process are largely unknown. The protogynous Hawaiian saddleback wrasse, Thalassoma duperrey, was used to investigate the biological pathway mediating the conversion of a social cue into neuroendocrine events regulating sex reversal. Because monoamines play an important role in the regulation of the HPG axis, they were selected as likely candidates for such a conversion. To determine if monoamines could affect sex reversal, drugs affecting monoamines were used in an attempt to either induce sex reversal under non-permissive conditions, or prevent sex reversal under permissive conditions. Increasing norepinephrine or blocking dopamine or serotonin lead to sex reversal in experimental animals under non-permissive conditions. Increasing serotonin blocked sex reversal under permissive conditions, while blocking dopamine or norepinephrine retarded the process. The results presented here demonstrate that monoamines contribute significantly to the control sex reversal. Norepinephrine stimulates initiation and completion of gonadal sex of reversal as well as color change perhaps directly via its effects on the HPG axis. Dopamine exercises inhibitory action on the initiation of sex reversal while 5-HT inhibits both initiation and completion of sex reversal. The serotonergic system appears to be an integral part of the pathway mediating the conversion of a social cue into a

  18. Design and Experiment of 1LFQ-325 Pneumatic Reversible Plough

    OpenAIRE

    Zheng, Xuan; Chen, Xuefeng; Qin, Chaomin; Jia, Libo

    2013-01-01

    A pneumatic reversible plough is developed, which complements to the tractor of 25.7-36.8 kW. The plough adopts the cylinder as reversing mechanism between the right and left plough bodies, and the cylinder can substitute the mechanical reversing mechanism. The pneumatic turnover allows the plough to be operated easily and turned over flexibly. Field experiment results show that indicators of plough performance meet the requirements of the relevant national standards.

  19. How manufacturers can use their reverse supply chain: a typology of reverse supply chain roles

    DEFF Research Database (Denmark)

    Larsen, Samuel; Jacobsen, Peter

    2014-01-01

    While traditional forward supply chains end with customer markets, the reverse supply chain (RSC) both begins and ends with the firm’s markets. The study applies the prevalent conceptual RSC‐description in the theoretical field by Guide and Van Wassenhove (2009). In the description, the RSC begins...... is not explicitly part of the description, this study does include them as disposition strategies. Although some RSC topics have been fairly well‐addressed in extant literature (e.g. product acquisition, inventory models and product disassembly), the RSC‐topic remains under‐explored (Pohkarel and Mutha, 2009...... the reverse logistical processes required for supporting a liberal return policy, etc. Based on extant literature from the supply chain management and OM fields, this study develops a conceptual typology of what roles the RSC can play in the firm’s efforts of achieving higher overall economic profits. Each...

  20. Magnetic islands at the field reversal surface in reversed field pinches

    International Nuclear Information System (INIS)

    Pinsker, R.I.; Reiman, A.H.

    1985-09-01

    In the reversed field pinch (RFP), magnetic field perturbations having zero poloidal mode number and any toroidal mode number are resonant at the field reversal surface. Such perturbations are a particular threat to the RFP because of their weak radial dependence at low toroidal mode number, and because the toroidal field ripple is essentially of this type. The widths of the resulting islands are calculated in this paper. The self-consistent plasma response is included through the assumption that the plasma relaxes to a Taylor force-free state. The connection with linear tearing mode theory is established for those limits where arbitrarily large islands result from infinitesimal perturbations. Toroidal effects are considered, and application of the theory to RFP experiments is discussed

  1. Thermodynamic reversibility and irreversibility of the reverse transformation in stabilized Cu-Zn-Al martensite

    International Nuclear Information System (INIS)

    Kustov, S.; Corro, M.; Pons, J.; Cesari, E.; Van Humbeeck, J.

    2006-01-01

    It has been shown that both pinning- (mechanical) and reordering-induced (chemical) stabilization components contribute to the overall stabilization effect. An algorithm has been developed for quantitative analysis of the chemical and mechanical stabilization components, using routine calorimetry results. The basic idea underlying this algorithm is that chemical and mechanical stabilization components stem, respectively, from the factors, affecting thermodynamically reversible and irreversible factors during the first reverse transformation of the stabilized martensite. On a thermodynamical level, application of the suggested algorithm has been illustrated using experimental calorimetry results for a Cu-Zn-Al alloy. Here we report analysis of pinning and reordering processes on a microscopic scale, using experimental data on non-linear anelasticity in the same Cu-Zn-Al alloy to track different spatial and temporal localization of these processes during martensite ageing

  2. Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin

    Science.gov (United States)

    Roche, Camille J.; Dantsker, David; Heller, Elizabeth R.; Sabat, Joseph E.; Friedman, Joel M.

    2013-08-01

    Hydration waters impact protein dynamics. Dissecting the interplay between hydration waters and dynamics requires a protein that manifests a broad range of dynamics. Proteins in reverse micelles (RMs) have promise as tools to achieve this objective because the water content can be manipulated. Hemoglobin is an appropriate tool with which to probe hydration effects. We describe both a protocol for hemoglobin encapsulation in reverse micelles and a facile method using PEG and cosolvents to manipulate water content. Hydration properties are probed using the water-sensitive fluorescence from Hb bound pyranine and covalently attached Badan. Protein dynamics are probed through ligand recombination traces derived from photodissociated carbonmonoxy hemoglobin on a log scale that exposes the potential role of both α and β solvent fluctuations in modulating protein dynamics. The results open the possibility of probing hydration level phenomena in this system using a combination of NMR and optical probes.

  3. Comparison of multiplex reverse transcription-PCR-enzyme ...

    African Journals Online (AJOL)

    Comparison of multiplex reverse transcription-PCR-enzyme hybridization assay with immunofluorescence techniques for the detection of four viral respiratory pathogens in pediatric community acquired pneumonia.

  4. Microscopic Investigation of Reversible Nanoscale Surface Size Dependent Protein Conjugation

    Directory of Open Access Journals (Sweden)

    Michael A. Carpenter

    2009-05-01

    Full Text Available Aβ1-40 coated 20 nm gold colloidal nanoparticles exhibit a reversible color change as pH is externally altered between pH 4 and 10. This reversible process may contain important information on the initial reversible step reported for the fibrillogenesis of Aβ (a hallmark of Alzheimer’s disease. We examined this reversible color change by microscopic investigations. AFM images on graphite surfaces revealed the morphology of Aβ aggregates with gold colloids. TEM images clearly demonstrate the correspondence between spectroscopic features and conformational changes of the gold colloid.

  5. Making radioactive wastes governable. Deep storage challenged by reversibility

    International Nuclear Information System (INIS)

    Gonnot, Francois-Michel; Dupuis, Marie-Claude; Aparicio, Luis; Barthe, Yannick; Cezanne-Bert, Pierrick; Chateauraynaud, Francis

    2010-09-01

    This book addresses the principle of reversibility in the field of radioactive waste management. The first contribution discusses the political qualities of technologies and analyses the different action modes associated with the different proposed management solutions (it shows that different decision models and safety approaches are associated with different technical arrangements). The second contribution comments the present posture of the ANDRA regarding the project of creation of a reversible deep storage centre, and proposes a definition of reversibility which relates scientific and technique development and decision process. The third contribution comments the results of a study on arguments about the notion of reversibility in France

  6. Reclaimable Thermally Reversible Polymers for AM Feedstock, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) proposes to design and develop thermally-reversible polymeric materials that will function as reprocessable thermosetting...

  7. Reversible Control of Anisotropic Electrical Conductivity using Colloidal Microfluidic Networks

    National Research Council Canada - National Science Library

    Beskok, Ali; Bevan, Michael; Lagoudas, Dimitris; Ounaies, Zoubeida; Bahukudumbi, Pradipkumar; Everett, William

    2007-01-01

    This research addresses the tunable assembly of reversible colloidal structures within microfluidic networks to engineer multifunctional materials that exhibit a wide range of electrical properties...

  8. Reversal of Hartmann's procedure following acute diverticulitis: is timing everything?

    LENUS (Irish Health Repository)

    Fleming, Fergal J

    2012-02-01

    BACKGROUND: Patients who undergo a Hartmann\\'s procedure may not be offered a reversal due to concerns over the morbidity of the second procedure. The aims of this study were to examine the morbidity post reversal of Hartmann\\'s procedure. METHODS: Patients who underwent a Hartmann\\'s procedure for acute diverticulitis (Hinchey 3 or 4) between 1995 and 2006 were studied. Clinical factors including patient comorbidities were analysed to elucidate what preoperative factors were associated with complications following reversal of Hartmann\\'s procedure. RESULTS: One hundred and ten patients were included. Median age was 70 years and 56% of the cohort were male (n = 61). The mortality and morbidity rate for the acute presentation was 7.3% (n = 8) and 34% (n = 37) respectively. Seventy six patients (69%) underwent a reversal at a median of 7 months (range 3-22 months) post-Hartmann\\'s procedure. The complication rate in the reversal group was 25% (n = 18). A history of current smoking (p = 0.004), increasing time to reversal (p = 0.04) and low preoperative albumin (p = 0.003) were all associated with complications following reversal. CONCLUSIONS: Reversal of Hartmann\\'s procedure can be offered to appropriately selected patients though with a significant (25%) morbidity rate. The identification of potential modifiable factors such as current smoking, prolonged time to reversal and low preoperative albumin may allow optimisation of such patients preoperatively.

  9. Application of industrial CT in reverse engineering technology

    International Nuclear Information System (INIS)

    Fang Liyong; Li Hui; Bai Jinping; Li Bailin

    2013-01-01

    The basic principle and basic steps of reverse engineering technology based on industrial CT are described. The recent research progresses and situation at home and abroad of reverse engineering technology based on industrial CT image are respectively described, analyzed and summarized from two routes which are surface segmentation and volume segmentation. An example of conch is used to exhibit the results from the two routes in reverse engineering technology based on industrial CT image. Finally, some difficulties in application and the future developments of reverse engineering technology based on industrial CT are prospected. (authors)

  10. Automatic Error Recovery in Robot Assembly Operations Using Reverse Execution

    DEFF Research Database (Denmark)

    Laursen, Johan Sund; Schultz, Ulrik Pagh; Ellekilde, Lars-Peter

    2015-01-01

    , in particular for small-batch productions. As an alternative, we propose a system for automatically handling certain classes of errors instead of preventing them. Specifically, we show that many operations can be automatically reversed. Errors can be handled through automatic reverse execution of the control...... program to a safe point, from which forward execution can be resumed. This paper describes the principles behind automatic reversal of robotic assembly operations, and experimentally demonstrates the use of a domain-specific language that supports automatic error handling through reverse execution. Our...

  11. Mass transfer with complex reversible chemical reactions—II. parallel reversible chemical reactions

    OpenAIRE

    Versteeg, G.F.; Kuipers, J.A.M.; Beckum, F.P.H. van; Swaaij, W.P.M. van

    1990-01-01

    An absorption model has been developed which can be used to calculate rapidly absorption rates for the phenomenon mass transfer accompanied by multiple complex parallel reversible chemical reactions. This model can be applied for the calculation of the mass transfer rates, enhancement factors and concentration profiles for a wide range of processes and conditions, for both film and penetration model. With the aid of this mass transfer model it is demonstrated that the absorption rates in syst...

  12. Removal of radionuclides in drinking water by membrane treatment using ultrafiltration, reverse osmosis and electrodialysis reversal

    International Nuclear Information System (INIS)

    Montaña, M.; Camacho, A.; Serrano, I.; Devesa, R.; Matia, L.; Vallés, I.

    2013-01-01

    A pilot plant had been built to test the behaviour of ultrafiltration (UF), reverse osmosis (RO), and electrodialysis reversal (EDR) in order to improve the quality of the water supplied to Barcelona metropolitan area from the Llobregat River. This paper presents results from two studies to reduce natural radioactivity. The results from the pilot plant with four different scenarios were used to design the full-scale treatment plant built (SJD WTP). The samples taken at different steps of the treatment were analysed to determine gross alpha, gross beta and uranium activity. The results obtained revealed a significant improvement in the radiological water quality provided by both membrane techniques (RO and EDR showed removal rates higher than 60%). However, UF did not show any significant removal capacity for gross alpha, gross beta or uranium activities. RO was better at reducing the radiological parameters studied and this treatment was selected and applied at the full scale treatment plant. The RO treatment used at the SJD WTP reduced the concentration of both gross alpha and gross beta activities and also produced water of high quality with an average removal of 95% for gross alpha activity and almost 93% for gross beta activity at the treatment plant. -- Highlights: ► A study with a pilot plant using different membranes technologies was made. ► Big reduction on natural uranium and 40 K by reverse osmosis was found. ► Pilot plant and full-scale treatment plant behave similarly

  13. Multiple Memory Structure Bit Reversal Algorithm Based on Recursive Patterns of Bit Reversal Permutation

    Directory of Open Access Journals (Sweden)

    K. K. L. B. Adikaram

    2014-01-01

    Full Text Available With the increasing demand for online/inline data processing efficient Fourier analysis becomes more and more relevant. Due to the fact that the bit reversal process requires considerable processing time of the Fast Fourier Transform (FFT algorithm, it is vital to optimize the bit reversal algorithm (BRA. This paper is to introduce an efficient BRA with multiple memory structures. In 2009, Elster showed the relation between the first and the second halves of the bit reversal permutation (BRP and stated that it may cause serious impact on cache performance of the computer, if implemented. We found exceptions, especially when the said index mapping was implemented with multiple one-dimensional memory structures instead of multidimensional or one-dimensional memory structure. Also we found a new index mapping, even after the recursive splitting of BRP into equal sized slots. The four-array and the four-vector versions of BRA with new index mapping reported 34% and 16% improvement in performance in relation to similar versions of Linear BRA of Elster which uses single one-dimensional memory structure.

  14. Reversible pumped hydro - benefits and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Torbjoern K.; Walseth, Eve C.

    2010-07-01

    Full text: The Norwegian hydro power system is dominated with high head turbines, Pelton and Francis with high capacity in the reservoirs. Originally they were built for secure energy supply. In the system there are also reversible pump turbine (RPT) plants where in times with spare energy, made it possible to pump water from the lower reservoir to the higher. Again the idea was to secure energy supply, which meant pumping in early autumn to fill the reservoirs for winter. In the recent years, a more active use of the RPT plants has been actualized. The free market made price difference between night and day interesting, hence a more frequent pumping was desirable. In the coming years, new-renewable energy sources will utterly enhance a more active use of the RPT plants. More active use of the RPT plants means more frequent starts and stops, both in pumping and in turbine mode. There are a lot of challenges in adopting a new strategy for operating the machinery. More effective start equipment is required. The machinery will be exposed to more frequent dynamic loads; the turbines will be run at part- and full load. The existing RPT plants are connected to huge reservoirs. That means the RPTs are not only for short sighted power regulations, as many RPT-plants in Europe, but are also capable for a substantial energy production. In Norway, the nature is very suitable for RPT plants, both in connection with existing power plants, were reservoirs and conduits are already established, and standing alone with a minimum of energy production. RPTs are, as a design, a compromise between effective generating and stable as well as effective pumping. Stable pumping often results in very steep flow-speed characteristics when operating as a turbine. When dealing with hydraulic transients these characteristics cause a higher change in flow and torque leading to instability during start-up and possible off-design operation point. The instability slows down the synchronization

  15. From reverse transcription to human brain tumors

    Directory of Open Access Journals (Sweden)

    Dmitrenko V. V.

    2013-05-01

    Full Text Available Reverse transcriptase from avian myeloblastosis virus (AMV was the subject of the study, from which the investi- gations of the Department of biosynthesis of nucleic acids were started. Production of AMV in grams quantities and isolation of AMV reverse transcriptase were established in the laboratory during the seventies of the past cen- tury and this initiated research on the cDNA synthesis, cloning and investigation of the structure and functions of the eukaryotic genes. Structures of salmon insulin and insulin-like growth factor (IGF family genes and their transcripts were determined during long-term investigations. Results of two modern techniques, microarray-ba- sed hybridization and SAGE, were used for the identification of the genes differentially expressed in astrocytic gliomas and human normal brain. Comparison of SAGE results on the genes overexpressed in glioblastoma with the results of microarray analysis revealed a limited number of common genes. 105 differentially expressed genes, common to both methods, can be included in the list of candidates for the molecular typing of glioblastoma. The first experiments on the classification of glioblastomas based on the data of the 20 genes expression were conducted by using of artificial neural network analysis. The results of these experiments showed that the expression profiles of these genes in 224 glioblastoma samples and 74 normal brain samples could be according to the Koho- nen’s maps. The CHI3L1 and CHI3L2 genes of chitinase-like cartilage protein were revealed among the most overexpressed genes in glioblastoma, which could have prognostic and diagnostic potential. Results of in vitro experiments demonstrated that both proteins, CHI3L1 and CHI3L2, may initiate the phosphorylation of ERK1/ ERK2 and AKT kinases leading to the activation of MAPK/ERK1/2 and PI3K/AKT signaling cascades in human embryonic kidney 293 cells, human glioblastoma U87MG, and U373 cells. The new human cell line

  16. Photophysical properties of pyronin dyes in reverse micelles of AOT

    Energy Technology Data Exchange (ETDEWEB)

    Bayraktutan, Tuğba; Meral, Kadem; Onganer, Yavuz, E-mail: yonganer@atauni.edu.tr

    2014-01-15

    The photophysical properties of pyronin B (PyB) and pyronin Y (PyY) in reverse micelles formed with water/sodium bis (2-ethyl-1-hexyl) sulfosuccinate (AOT)/n-heptane were investigated by UV–vis absorption, steady-state and time-resolved fluorescence spectroscopy techniques. This study was carried out a wide range of reverse micelle sizes, with hydrodynamic radii ranging from 1.85 to 9.38 nm. Significant photophysical parameters as band shifts, fluorescence quantum yields and fluorescence lifetimes were determined to understand how photophysical and spectroscopic features of the dye compounds were affected by the variation of reverse micelle sizes. In this regard, control of reverse micelle size by changing W{sub 0}, the molar ratio of water to surfactant, allowed tuning the photophysical properties of the dyes in organic solvent via reverse micelle. Non-fluorescent H-aggregates of pyronin dyes were observed for the smaller reverse micelles whereas an increase in the reverse micelle size induced an increment in the amount of dye monomers instead of dye aggregates. Thus, the fluorescence intensities of the dyes were improved by increasing W{sub 0} due to the predomination of the fluorescent dye monomers. As a result, the fluorescence quantum yields also increased. The fluorescence lifetimes of the dyes in the reverse micelles were determined by the time-resolved fluorescence decay studies. Evaluation of the fluorescence lifetimes calculated for pyronin dyes in the reverse micelles showed that the size of reverse micelle affected the fluorescence lifetimes of pyronin dyes. -- Highlights: • The photophysical properties of pyronin dyes were examined by spectroscopic techniques. • Optical properties of the dyes were tuned by changing of W{sub 0} values. • The fluorescence lifetime and quantum yield values of the dyes in reverse micelles were discussed.

  17. Visual hydrogen detector with variable reversibility

    Science.gov (United States)

    Muradov, Nazim (Inventor)

    2011-01-01

    Methods, processes and compositions are provided for a visual or chemochromic hydrogen-detector with variable or tunable reversible color change. The working temperature range for the hydrogen detector is from minus 100.degree. C. to plus 500.degree. C. A hydrogen-sensitive pigment, including, but not limited to, oxides, hydroxides and polyoxo-compounds of tungsten, molybdenum, vanadium, chromium and combinations thereof, is combined with nano-sized metal activator particles and preferably, coated on a porous or woven substrate. In the presence of hydrogen, the composition rapidly changes its color from white or light-gray or light-tan to dark gray, navy-blue or black depending on the exposure time and hydrogen concentration in the medium. After hydrogen exposure ceases, the original color of the hydrogen-sensitive pigment is restored, and the visual hydrogen detector can be used repeatedly. By changing the composition of the hydrogen-sensitive pigment, the time required for its complete regeneration is varied from a few seconds to several days.

  18. Breast cancer detection using time reversal

    Science.gov (United States)

    Sheikh Sajjadieh, Mohammad Hossein

    Breast cancer is the second leading cause of cancer death after lung cancer among women. Mammography and magnetic resonance imaging (MRI) have certain limitations in detecting breast cancer, especially during its early stage of development. A number of studies have shown that microwave breast cancer detection has potential to become a successful clinical complement to the conventional X-ray mammography. Microwave breast imaging is performed by illuminating the breast tissues with an electromagnetic waveform and recording its reflections (backscatters) emanating from variations in the normal breast tissues and tumour cells, if present, using an antenna array. These backscatters, referred to as the overall (tumour and clutter) response, are processed to estimate the tumour response, which is applied as input to array imaging algorithms used to estimate the location of the tumour. Due to changes in the breast profile over time, the commonly utilized background subtraction procedures used to estimate the target (tumour) response in array processing are impractical for breast cancer detection. The thesis proposes a new tumour estimation algorithm based on a combination of the data adaptive filter with the envelope detection filter (DAF/EDF), which collectively do not require a training step. After establishing the superiority of the DAF/EDF based approach, the thesis shows that the time reversal (TR) array imaging algorithms outperform their conventional conterparts in detecting and localizing tumour cells in breast tissues at SNRs ranging from 15 to 30dB.

  19. Kinetic stability of field-reversed configurations

    International Nuclear Information System (INIS)

    Staudenmeier, J.L.; Hsiao, M.-Y.

    1991-01-01

    The internal tilt mode is considered to be the biggest threat to Field-Reversed Configuration (FRC) global stability. The tilt stability of the FRC is studied using the MHD, Hall MHD, and the Vlasov-fluid (Vlasov ions, cold massless fluid electrons) models. Nonlinear Hall MHD calculations showed that the FRC was stable to the tilt mode when the s value of the FRC was below a critical value that was dependent on plasma length. The critical s value is larger for longer plasma equilibria. The stability of FRC's with toroidal field was studied with a linear initial value MHD code. The calculations showed an axial perturbation wavelength of the most unstable eigenfunction that was consistent with internal probe measurements made on translated FRC's. Linear Vlasov-fluid eigenvalue calculations showed that kinetic ion effects can change both the growth rate and the structure of the eigenfunctions when compared to the corresponding MHD modes. Calculations on short FRC equilibria indicate that MHD is not the appropriate small gyroradius limit of the Vlasov-fluid model because the axial transit time of a thermal ion is approximately equal to an MHD growth time for the tilt mode. Calculations were done using a small number of unstable MHD eigenfunctions as basis functions in order to reduce the dimensionality of the stability problem. The results indicated that this basis set can produce inaccurate growth rates at large value for s for some equilibria

  20. Posterior Reversible Leukoencephalopathy Syndrome Associated with Pazopanib

    Directory of Open Access Journals (Sweden)

    Robert Foerster

    2013-04-01

    Full Text Available A 62-year-old female patient with metastatic renal cell carcinoma under third-line treatment with pazopanib for 8 weeks suddenly developed severe headaches, grand mal seizures and paresis of the left arm in combination with gait instability as well as nausea and vomiting during her vacation abroad. The emergency physician measured systolic blood pressure values over 300 mm Hg and suspected a stroke. The CT imaging without contrast agent in a local hospital did not show any pathologic findings despite bone metastases. The colleagues suspected cerebral metastases or meningeosis carcinomatosa and referred the patient to our department for further diagnostics and treatment planning. An MRI scan ruled out the suspected cerebral metastases or meningeosis carcinomatosa, but showed signs of reversible posterior leukoencephalopathy syndrome (RPLS in the form of band-like hyperintensities as a sign of cytotoxic edema in the gray and white matter of the left parietal lobe. The patient then reported that similar blood pressure values had been measured shortly after the start of a first-line therapy with sunitinib, so that we discontinued the current treatment with pazopanib. Within 6 days the neurologic symptoms vanished and the patient was discharged. An intermittent hypertension persisted. A follow-up MRI 3 weeks later showed an RPLS-typical cortical infarction in the affected area. RPLS should be considered as the actual reason for neurologic findings in hypertensive patients with known metastatic cancers under tyrosine kinase inhibitor therapy.

  1. Reversed field pinch reactor study 3

    International Nuclear Information System (INIS)

    Hollis, A.A.; Mitchell, J.T.D.

    1977-12-01

    This report, the third of a series on the Reversed Field Pinch Reactor, describes a preliminary concept of the engineering design and layout of this pulsed toroidal reactor, which uses the stable plasma behaviour first observed in ZETA. The basic parameters of the 600 MW(e) reactor are taken from a companion study by Hancox and Spears. The plasma volume is 1.75m minor radius and 16m major radius surrounded by a 1.8m blanket-shield region - with the blanket divided into 14 removable segments for servicing. The magnetic confinement system consists of 28 toroidal field coils situated just outside the blanket and inside the poloidal and vertical field coils and all coils have normal copper conductors. The requirement to incorporate a conducting shell at the front of the blanket to provide a short-time plasma stability has a marked effect on the design. It sets the size of the blanket segment and the scale of the servicing operations, limits the breeding gain and complicates the blanket cooling and its integration with the heat engine. An extensive study will be required to confirm the overall reactor potential of the concept. (author)

  2. Remediating biofouling of reverse osmosis membranes

    International Nuclear Information System (INIS)

    Siler, J.L.

    1991-01-01

    Several potential additives and the use of influent pH adjustment were examined to remediated the biofouling problem of the ETF reverse osmosis (RO) system. Tests were conducted with simulated RO feed containing salt, metal hydroxides and bacteria. The addition of sodium hexametaphosphate (SHMP), sodium bisulfite, and adjusting the influent pH to 3 were each successful in reducing the RO biofouling. Little or no benefit was found from the use of a biofilm remover (Filmtec Alkaline Cleaner) or the use of surfactants (Surfynol or sodium lauryl sulfate). In addition, Surfynol use resulted in irreversible fouling and necessitated membrane replacement. At the water recoveries used in the ETF (>90%), sodium bisulfite addition resulted in the recovery of 70--90% of the flux and almost complete restoration of the DF to prefouled conditions. Based on the bench-scale tests completed, IWT would recommend that sodium bisulfite addition be tested at the ETF. This testing would involve optimizing the amount of bisulfite required. In addition, it is recommended that the addition of SHMP or influent pH adjustment be evaluated since the relative differences in labscale tests were small and scale-up effects could be present. The ETF operating permit allows each to be added

  3. How reversible is sea ice loss?

    Directory of Open Access Journals (Sweden)

    J. K. Ridley

    2012-02-01

    Full Text Available It is well accepted that increasing atmospheric CO2 results in global warming, leading to a decline in polar sea ice area. Here, the specific question of whether there is a tipping point in the sea ice cover is investigated. The global climate model HadCM3 is used to map the trajectory of sea ice area under idealised scenarios. The atmospheric CO2 is first ramped up to four times pre-industrial levels (4 × CO2, then ramped down to pre-industrial levels. We also examine the impact of stabilising climate at 4 × CO2 prior to ramping CO2 down to pre-industrial levels. Against global mean temperature, Arctic sea ice area is reversible, while the Antarctic sea ice shows some asymmetric behaviour – its rate of change slower, with falling temperatures, than its rate of change with rising temperatures. However, we show that the asymmetric behaviour is driven by hemispherical differences in temperature change between transient and stabilisation periods. We find no irreversible behaviour in the sea ice cover.

  4. Tensor network method for reversible classical computation

    Science.gov (United States)

    Yang, Zhi-Cheng; Kourtis, Stefanos; Chamon, Claudio; Mucciolo, Eduardo R.; Ruckenstein, Andrei E.

    2018-03-01

    We develop a tensor network technique that can solve universal reversible classical computational problems, formulated as vertex models on a square lattice [Nat. Commun. 8, 15303 (2017), 10.1038/ncomms15303]. By encoding the truth table of each vertex constraint in a tensor, the total number of solutions compatible with partial inputs and outputs at the boundary can be represented as the full contraction of a tensor network. We introduce an iterative compression-decimation (ICD) scheme that performs this contraction efficiently. The ICD algorithm first propagates local constraints to longer ranges via repeated contraction-decomposition sweeps over all lattice bonds, thus achieving compression on a given length scale. It then decimates the lattice via coarse-graining tensor contractions. Repeated iterations of these two steps gradually collapse the tensor network and ultimately yield the exact tensor trace for large systems, without the need for manual control of tensor dimensions. Our protocol allows us to obtain the exact number of solutions for computations where a naive enumeration would take astronomically long times.

  5. Reversed-Field Pinch Reactor (RFPR) concept

    International Nuclear Information System (INIS)

    Hagenson, R.L.; Krakowski, R.A.; Cort, G.E.

    1979-08-01

    A conceptual engineering design of a fusion reactor based on plasma confinement in a Reversed-Field Pinch (FRP) configuration is presented. A 50% atomic mixture of deuterium and tritium (DT) is ohmically heated to ignition by currents flowing in the toroidal plasma; this plasma current also inherently produces the confining magnetic fields in a toroidal chamber having a major and minor radii of 12.7 and 1.5 m, respectively. The DT plasma ignites in 2 to 3 s and burns at 10 to 20 keV for approx. 20 s to give a fuel burnup of approx. 50%. Tritium breeding occurs in a granular Li 2 O blanket which is packed around an array of radially oriented coolant tubes carrying a mixture of high-pressure steam and water. The slightly superheated steam emerging from this blanket would be used to drive a turbine directly. Low-pressure helium containing trace amounts of oxygen is circulated through the packed Li 2 O bed to extract the tritium. A 20-mm-thick copper first wall serves as a neutron multiplier, acts as a tritium barrier, and supports image currents to provide plasma stabilization on a 0.1-s timescale; external windings provide stability for longer times

  6. Double quick, double click reversible peptide "stapling".

    Science.gov (United States)

    Grison, Claire M; Burslem, George M; Miles, Jennifer A; Pilsl, Ludwig K A; Yeo, David J; Imani, Zeynab; Warriner, Stuart L; Webb, Michael E; Wilson, Andrew J

    2017-07-01

    The development of constrained peptides for inhibition of protein-protein interactions is an emerging strategy in chemical biology and drug discovery. This manuscript introduces a versatile, rapid and reversible approach to constrain peptides in a bioactive helical conformation using BID and RNase S peptides as models. Dibromomaleimide is used to constrain BID and RNase S peptide sequence variants bearing cysteine (Cys) or homocysteine ( h Cys) amino acids spaced at i and i + 4 positions by double substitution. The constraint can be readily removed by displacement of the maleimide using excess thiol. This new constraining methodology results in enhanced α-helical conformation (BID and RNase S peptide) as demonstrated by circular dichroism and molecular dynamics simulations, resistance to proteolysis (BID) as demonstrated by trypsin proteolysis experiments and retained or enhanced potency of inhibition for Bcl-2 family protein-protein interactions (BID), or greater capability to restore the hydrolytic activity of the RNAse S protein (RNase S peptide). Finally, use of a dibromomaleimide functionalized with an alkyne permits further divergent functionalization through alkyne-azide cycloaddition chemistry on the constrained peptide with fluorescein, oligoethylene glycol or biotin groups to facilitate biophysical and cellular analyses. Hence this methodology may extend the scope and accessibility of peptide stapling.

  7. Scaling properties of paleomagnetic reversal sequence

    Directory of Open Access Journals (Sweden)

    S. S. Ivanov

    1996-01-01

    Full Text Available The history of reversals of main geomagnetic field during last 160 My is analyzed as a sequence of events, presented as a point set on the time axis. Different techniques were applied including the method of boxcounting, dispersion counter-scaling, multifractal analysis and examination of attractor behaviour in multidimensional phase space. The existence of a crossover point at time interval 0.5-1.0 My was clearly identified, dividing the whole time range into two subranges with different scaling properties. The long-term subrange is characterized by monofractal dimension 0.88 and by an attractor, whose correlation dimension converges to 1.0, that provides evidence of a deterministic dynamical system in this subrange, similar to most existing dynamo models. In the short-term subrange the fractal dimension estimated by different methods varies from 0.47 to 0.88 and the dimensionality of the attractor is obtained to be about 3.7. These results are discussed in terms of non-linear superposition of processes in the Earth's geospheres.

  8. FARADAY ROTATION: EFFECT OF MAGNETIC FIELD REVERSALS

    International Nuclear Information System (INIS)

    Melrose, D. B.

    2010-01-01

    The standard formula for the rotation measure (RM), which determines the position angle, ψ = RMλ 2 , due to Faraday rotation, includes contributions only from the portions of the ray path where the natural modes of the plasma are circularly polarized. In small regions of the ray path where the projection of the magnetic field on the ray path reverses sign (called QT regions) the modes are nearly linearly polarized. The neglect of QT regions in estimating RM is not well justified at frequencies below a transition frequency where mode coupling changes from strong to weak. By integrating the polarization transfer equation across a QT region in the latter limit, I estimate the additional contribution Δψ needed to correct this omission. In contrast with a result proposed by Broderick and Blandford, Δψ is small and probably unobservable. I identify a new source of circular polarization, due to mode coupling in an asymmetric QT region. I also identify a new circular-polarization-dependent correction to the dispersion measure at low frequencies.

  9. FARADAY ROTATION: EFFECT OF MAGNETIC FIELD REVERSALS

    Energy Technology Data Exchange (ETDEWEB)

    Melrose, D B [SIfA, School of Physics, University of Sydney, NSW 2006 (Australia)

    2010-12-20

    The standard formula for the rotation measure (RM), which determines the position angle, {psi} = RM{lambda}{sup 2}, due to Faraday rotation, includes contributions only from the portions of the ray path where the natural modes of the plasma are circularly polarized. In small regions of the ray path where the projection of the magnetic field on the ray path reverses sign (called QT regions) the modes are nearly linearly polarized. The neglect of QT regions in estimating RM is not well justified at frequencies below a transition frequency where mode coupling changes from strong to weak. By integrating the polarization transfer equation across a QT region in the latter limit, I estimate the additional contribution {Delta}{psi} needed to correct this omission. In contrast with a result proposed by Broderick and Blandford, {Delta}{psi} is small and probably unobservable. I identify a new source of circular polarization, due to mode coupling in an asymmetric QT region. I also identify a new circular-polarization-dependent correction to the dispersion measure at low frequencies.

  10. Asymmetric Cherenkov acoustic reverse in topological insulators

    Science.gov (United States)

    Smirnov, Sergey

    2014-09-01

    A general phenomenon of the Cherenkov radiation known in optics or acoustics of conventional materials is a formation of a forward cone of, respectively, photons or phonons emitted by a particle accelerated above the speed of light or sound in those materials. Here we suggest three-dimensional topological insulators as a unique platform to fundamentally explore and practically exploit the acoustic aspect of the Cherenkov effect. We demonstrate that by applying an in-plane magnetic field to a surface of a three-dimensional topological insulator one may suppress the forward Cherenkov sound up to zero at a critical magnetic field. Above the critical field the Cherenkov sound acquires pure backward nature with the polar distribution differing from the forward one generated below the critical field. Potential applications of this asymmetric Cherenkov reverse are in the design of low energy electronic devices such as acoustic ratchets or, in general, in low power design of electronic circuits with a magnetic field control of the direction and magnitude of the Cherenkov dissipation.

  11. Durability evaluation of reversible solid oxide cells

    Science.gov (United States)

    Zhang, Xiaoyu; O'Brien, James E.; O'Brien, Robert C.; Housley, Gregory K.

    2013-11-01

    An experimental investigation on the performance and durability of single solid oxide cells (SOCs) is under way at the Idaho National Laboratory. Reversible operation of SOCs includes electricity generation in the fuel cell mode and hydrogen generation in the electrolysis mode. Degradation is a more significant issue when operating SOCs in the electrolysis mode. In order to understand and mitigate the degradation issues in high temperature electrolysis, single SOCs with different configurations from several manufacturers have been evaluated for initial performance and long-term durability. Cells were obtained from four industrial partners. Cells from Ceramatec Inc. and Materials and Systems Research Inc. (MSRI) showed improved durability in electrolysis mode compared to previous stack tests. Cells from Saint Gobain Advanced Materials Inc. (St. Gobain) and SOFCPower Inc. demonstrated stable performance in the fuel cell mode, but rapid degradation in the electrolysis mode, especially at high current density. Electrolyte-electrode delamination was found to have a significant impact on degradation in some cases. Enhanced bonding between electrolyte and electrode and modification of the electrode microstructure helped to mitigate degradation. Polarization scans and AC impedance measurements were performed during the tests to characterize cell performance and degradation.

  12. Coupled transport in field-reversed configurations

    Science.gov (United States)

    Steinhauer, L. C.; Berk, H. L.; TAE Team

    2018-02-01

    Coupled transport is the close interconnection between the cross-field and parallel fluxes in different regions due to topological changes in the magnetic field. This occurs because perpendicular transport is necessary for particles or energy to leave closed field-line regions, while parallel transport strongly affects evolution of open field-line regions. In most toroidal confinement systems, the periphery, namely, the portion with open magnetic surfaces, is small in thickness and volume compared to the core plasma, the portion with closed surfaces. In field-reversed configurations (FRCs), the periphery plays an outsized role in overall confinement. This effect is addressed by an FRC-relevant model of coupled particle transport that is well suited for immediate interpretation of experiments. The focus here is particle confinement rather than energy confinement since the two track together in FRCs. The interpretive tool yields both the particle transport rate χn and the end-loss time τǁ. The results indicate that particle confinement depends on both χn across magnetic surfaces throughout the plasma and τǁ along open surfaces and that they provide roughly equal transport barriers, inhibiting particle loss. The interpretation of traditional FRCs shows Bohm-like χn and inertial (free-streaming) τǁ. However, in recent advanced beam-driven FRC experiments, χn approaches the classical rate and τǁ is comparable to classic empty-loss-cone mirrors.

  13. Solar Powered Reverse Trash Vendo Machine

    Directory of Open Access Journals (Sweden)

    Alexis John M. Rubio

    2016-05-01

    Full Text Available –The study was conducted with the purpose of developing a Solar Powered Reverse Trash Vendo Machine that aims to encourage people to engage in recycling and to diminish the practice of improper waste disposal in thePhilippines. The device used a Gizduino X ATMega 1281 as its main processing module along with a Gizduino 644 microcontroller board, anda GSM Shield module for communication. Arduino1.6 IDE is used to program the Gizduinoboards. The device is powered by a 15V rechargeable battery, which is charged by a solar panel retrofitted at the roof of the device, this is to promote energy conservation, and green engineering principles in the development of the study.The device can process empty plastic bottles (500ml. max with a base diameter of 3.5 inches, and aluminium cans. These recyclable materials are placed inside the machine and is scanned, then crushed and placed in a bin. An inductive sensor is used to detect either the material is a plastic bottle or an aluminium can. To compensate the user for recycling, an equivalent monetary value will be dispensed. The owner of the device can check the status of the coin dispenser and bins through an Android messaging application developed using the Eclipse IDE and the Java programming language, and when a certain limit is reached by the coin dispenser or the trash bins, an automatic text message notification will be sent to the owner.

  14. N-Acetylcysteine Reverses Cocaine Induced Metaplasticity

    Science.gov (United States)

    Moussawi, Khaled; Pacchioni, Alejandra; Moran, Megan; Olive, M. Foster; Gass, Justin T.; Lavin, Antonieta; Kalivas, Peter W

    2009-01-01

    Cocaine addiction is characterized by an impaired ability to develop adaptive behaviors that can compete with cocaine seeking, implying a deficit in the ability to induce plasticity in cortico-accumbens circuitry critical for regulating motivated behavior. RWe found that rats withdrawn from cocaine self-administration had a marked in vivo deficit in the ability to develop long-term potentation (LTP) and depression (LTD) in the nucleus accumbens core subregion following stimulation of prefrontal cortex. N-acetylcysteine treatment prevents relapse in animal models and craving in humans by activating cystine-glutamate exchange and thereby stimulating extrasynaptic metabotropic glutamate receptors (mGluR). N-acetylcysteine treatment restored the ability to induce LTP and LTD by indirectly stimulating mGluR2/3 and mGluR5, respectively. Cocaine self-administration induces metaplasticity that inhibits the further induction of synaptic plasticity, and this impairment can be reversed by N-acetylcysteine, a drug that also prevents relapse. PMID:19136971

  15. Reversed-field pinch fusion reactor

    International Nuclear Information System (INIS)

    Hagenson, R.L.; Krakowski, R.A.

    1980-01-01

    A conceptual engineering design of a fusion reactor based on plasma confinement in a toroidal Reversed-Field Pinch (RFP) configuration is described. The plasma is ohmically ignited by toroidal plasma currents which also inherently provide the confining magnetic fields in a toroidal chamber having major and minor radii of 12.7 and 1.5 m, respectively. The DT plasma ignites in 2 to 3 s and undergoes a transient, unrefueled burn at 10 to 20 keV for approx. 20 s to give a DT burnup of approx. 50%. The 5-s dwell period between burn pulses for plasma quench and refueling allows steady-state operation of all thermal systems outside the first wall; no auxiliary thermal capacity is required. Tritium breeding occurs in a granular Li 2 O blanket which is packed around an array of radially oriented water/steam coolant tubes. The slightly superheated steam emerging from this blanket directly drives a turbine that produces electrical power at an efficiency of 30%. A borated-water shield is located immediately outside the thermal blanket to protect the superconducting magnet coils. Both the superconducting poloidal and toroidal field coils are energized by homopolar motor/generators. Accounting for all major energy sinks yields a cost-optimized system with a recirculating power fraction of 0.17; the power output is 750 MWe

  16. Diagnosis of reversible causes of coma.

    Science.gov (United States)

    Edlow, Jonathan A; Rabinstein, Alejandro; Traub, Stephen J; Wijdicks, Eelco F M

    2014-12-06

    Because coma has many causes, physicians must develop a structured, algorithmic approach to diagnose and treat reversible causes rapidly. The three main mechanisms of coma are structural brain lesions, diffuse neuronal dysfunction, and, rarely, psychiatric causes. The first priority is to stabilise the patient by treatment of life-threatening conditions, then to use the history, physical examination, and laboratory findings to identify structural causes and diagnose treatable disorders. Some patients have a clear diagnosis. In those who do not, the first decision is whether brain imaging is needed. Imaging should be done in post-traumatic coma or when structural brain lesions are probable or possible causes. Patients who do not undergo imaging should be reassessed regularly. If CT is non-diagnostic, a checklist should be used use to indicate whether advanced imaging is needed or evidence is present of a treatable poisoning or infection, seizures including non-convulsive status epilepticus, endocrinopathy, or thiamine deficiency. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Addictions Neuroclinical Assessment: A reverse translational approach.

    Science.gov (United States)

    Kwako, Laura E; Momenan, Reza; Grodin, Erica N; Litten, Raye Z; Koob, George F; Goldman, David

    2017-08-01

    Incentive salience, negative emotionality, and executive function are functional domains that are etiologic in the initiation and progression of addictive disorders, having been implicated in humans with addictive disorders and in animal models of addictions. Measures of these three neuroscience-based functional domains can capture much of the effects of inheritance and early exposures that lead to trait vulnerability shared across different addictive disorders. For specific addictive disorders, these measures can be supplemented by agent specific measures such as those that access pharmacodynamic and pharmacokinetic variation attributable to agent-specific gatekeeper molecules including receptors and drug-metabolizing enzymes. Herein, we focus on the translation and reverse translation of knowledge derived from animal models of addiction to the human condition via measures of neurobiological processes that are orthologous in animals and humans, and that are shared in addictions to different agents. Based on preclinical data and human studies, measures of these domains in a general framework of an Addictions Neuroclinical Assessment (ANA) can transform the assessment and nosology of addictive disorders, and can be informative for staging disease progression. We consider next steps and challenges for implementation of ANA in clinical care and research. This article is part of the Special Issue entitled "Alcoholism". Published by Elsevier Ltd.

  18. A reversible transform for seismic data processing

    International Nuclear Information System (INIS)

    Burnett, William A; Ferguson, Robert J

    2011-01-01

    We use the nonstationary equivalent of the Fourier shift theorem to derive a general one-dimensional integral transform for the application and removal of certain seismic data processing steps. This transform comes from the observation that many seismic data processing steps can be viewed as nonstationary shifts. The continuous form of the transform is exactly reversible, and the discrete form provides a general framework for unitary and pseudounitary imaging operators. Any processing step which can be viewed as a nonstationary shift in any domain is a special case of this transform. Nonstationary shifts generally produce coordinate distortions between input and output domains, and those that preserve amplitudes do not conserve the energy of the input signal. The nonstationary frequency distortions, time distortions and nonphysical energy changes inherent to such operations are predicted and quantified by this transform. Processing steps of this type are conventionally implemented using interpolation operators to map discrete data values between input and output coordinate frames. Although not explicitly derived to perform interpolation, the transform here assumes the Fourier basis to predict values of the input signal between sampling locations. We demonstrate how interpolants commonly used in seismic data processing and imaging approximate the proposed method. We find that our transform is equivalent to the conventional sinc interpolant with no truncation. Once the transform is developed, we demonstrate its numerical implementation by matrix–vector multiplication. As an example, we use our transform to apply and remove normal moveout

  19. Reverse control for humanoid robot task recognition.

    Science.gov (United States)

    Hak, Sovannara; Mansard, Nicolas; Stasse, Olivier; Laumond, Jean Paul

    2012-12-01

    Efficient methods to perform motion recognition have been developed using statistical tools. Those methods rely on primitive learning in a suitable space, for example, the latent space of the joint angle and/or adequate task spaces. Learned primitives are often sequential: A motion is segmented according to the time axis. When working with a humanoid robot, a motion can be decomposed into parallel subtasks. For example, in a waiter scenario, the robot has to keep some plates horizontal with one of its arms while placing a plate on the table with its free hand. Recognition can thus not be limited to one task per consecutive segment of time. The method presented in this paper takes advantage of the knowledge of what tasks the robot is able to do and how the motion is generated from this set of known controllers, to perform a reverse engineering of an observed motion. This analysis is intended to recognize parallel tasks that have been used to generate a motion. The method relies on the task-function formalism and the projection operation into the null space of a task to decouple the controllers. The approach is successfully applied on a real robot to disambiguate motion in different scenarios where two motions look similar but have different purposes.

  20. Reverse transcriptase inhibitors as potential colorectal microbicides.

    Science.gov (United States)

    Herrera, Carolina; Cranage, Martin; McGowan, Ian; Anton, Peter; Shattock, Robin J

    2009-05-01

    We investigated whether reverse transcriptase (RT) inhibitors (RTI) can be combined to inhibit human immunodeficiency virus type 1 (HIV-1) infection of colorectal tissue ex vivo as part of a strategy to develop an effective rectal microbicide. The nucleotide RTI (NRTI) PMPA (tenofovir) and two nonnucleoside RTI (NNRTI), UC-781 and TMC120 (dapivirine), were evaluated. Each compound inhibited the replication of the HIV isolates tested in TZM-bl cells, peripheral blood mononuclear cells, and colorectal explants. Dual combinations of the three compounds, either NRTI-NNRTI or NNRTI-NNRTI combinations, were more active than any of the individual compounds in both cellular and tissue models. Combinations were key to inhibiting infection by NRTI- and NNRTI-resistant isolates in all models tested. Moreover, we found that the replication capacities of HIV-1 isolates in colorectal explants were affected by single point mutations in RT that confer resistance to RTI. These data demonstrate that colorectal explants can be used to screen compounds for potential efficacy as part of a combination microbicide and to determine the mucosal fitness of RTI-resistant isolates. These findings may have important implications for the rational design of effective rectal microbicides.

  1. Tackling feline infectious peritonitis via reverse genetics.

    Science.gov (United States)

    Thiel, Volker; Thiel, Heinz-Jürgen; Tekes, Gergely

    2014-01-01

    Feline infectious peritonitis (FIP) is caused by feline coronaviruses (FCoVs) and represents one of the most important lethal infectious diseases of cats. To date, there is no efficacious prevention and treatment, and our limited knowledge on FIP pathogenesis is mainly based on analysis of experiments with field isolates. In a recent study, we reported a promising approach to study FIP pathogenesis using reverse genetics. We generated a set of recombinant FCoVs and investigated their pathogenicity in vivo. The set included the type I FCoV strain Black, a type I FCoV strain Black with restored accessory gene 7b, two chimeric type I/type II FCoVs and the highly pathogenic type II FCoV strain 79-1146. All recombinant FCoVs and the reference strain isolates were found to establish productive infections in cats. While none of the type I FCoVs and chimeric FCoVs induced FIP, the recombinant type II FCoV strain 79-1146 was as pathogenic as the parental isolate. Interestingly, an intact ORF 3c was confirmed to be restored in all viruses (re)isolated from FIP-diseased animals.

  2. Explaining Polarization Reversals in STEREO Wave Data

    Science.gov (United States)

    Breneman, A.; Cattell, C.; Wygant, J.; Kersten, K.; Wilson, L, B., III; Dai, L.; Colpitts, C.; Kellogg, P. J.; Goetz, K.; Paradise, A.

    2012-01-01

    Recently Breneman et al. reported observations of large amplitude lightning and transmitter whistler mode waves from two STEREO passes through the inner radiation belt (Lpaper. We show, with a combination of observations and simulated wave superposition, that these polarization reversals are due to the beating of an incident electromagnetic whistler mode wave at 21.4 kHz and linearly polarized, symmetric lower hybrid sidebands Doppler-shifted from the incident wave by +/-200 Hz. The existence of the lower hybrid waves is consistent with the parametric decay mechanism of Lee and Kuo whereby an incident whistler mode wave decays into symmetric, short wavelength lower hybrid waves and a purely growing (zero-frequency) mode. Like the lower hybrid waves, the purely growing mode is Doppler-shifted by 200 Hz as observed on STEREO. This decay mechanism in the upper ionosphere has been previously reported at equatorial latitudes and is thought to have a direct connection with explosive spread F enhancements. As such it may represent another dissipation mechanism of VLF wave energy in the ionosphere and may help to explain a deficit of observed lightning and transmitter energy in the inner radiation belts as reported by Starks et al.

  3. High Pressure Reverse Flow APS Engine

    Science.gov (United States)

    Senneff, J. M.

    1972-01-01

    A design and test demonstration effort was undertaken to evaluate the concept of the reverse flow engine for the APS engine application. The 1500 lb (6672 N) thrust engine was designed to operate on gaseous hydrogen and gaseous oxygen propellants at a mixture ratio of 4 and to achieve the objective performance of 435 sec (4266 Nsec/kg) specific impulse. Superimposed durability requirements called for a million-cycle capability with 50 hours duration. The program was undertaken as a series of tasks including the initial preliminary design, design of critical test components and finally, the design and demonstration of an altitude engine which could be used interchangeably to examine operating parameters as well as to demonstrate the capability of the concept. The program results are reported with data to indicate that all of the program objectives were met or exceeded within the course of testing on the program. The analysis effort undertaken is also reported in detail and supplemented with test data in some cases where prior definitions could not be made. The results are contained of these analyses as well as the test results conducted throughout the course of the program. Finally, the test data and analytical results were combined to allow recommendations for a flight weight design. This preliminary design effort is also detailed.

  4. Reversible myocardial ischaemia or irreversible myocardial fibrosis

    International Nuclear Information System (INIS)

    Mathey, D.; Hanrath, P.; Kupper, W.; Bleifeld, W.; Montz, R.; Knop, J.; Stritzke, P.; Kroeger, E.; Bleese, N.

    1978-01-01

    The results of biphasis 201 thallium ( 201 Tl) scanning were compared with those of coronary arteriography, left ventricular angiography and stress ECG in 56 patients with coronary artery disease and six with no evidence of heart disease. There were 104 201 Tl defects, 50 of them reversible. The defects were always located in the area supplied by a critically stenotic coronary artery. Correlation of regional wall motion with 201 Tl activity demonstrated that in all forms of abnormal wall motion there was either ischaemia or fibrosis. The resting LV angiogram thus does not make it possible to distinguish between myocardial ischaemia and fibrosis. Taking the LV angiogram as a standard, the rate of false-positive 201 Tl scintigrams was 5%, that of false-negative ones 23%. The biphasic 201 Tl scintigram was more sensitive than the stress ECG in detecting myocardial ischaemia. It furthermore made it possible to localize the ischaemic (or fibrotic) region within the LV and to estimate its size. (orig.) [de

  5. Appeals court reverses verdict favoring drug companies.

    Science.gov (United States)

    1995-06-02

    An appeals court reversed a verdict favoring drug companies after the widow of a hemophiliac, whose death was linked to HIV-tainted blood products, sued four pharmaceutical companies to pay damages. The four companies, Alpha Therapeutic Corp., Miles Laboratories Inc., Armour Pharmaceutical Co., and Baxter Travenol Laboratories Inc., provided Factor VIII, a clotting concentrate, to [name removed] [name removed], the plaintiff's husband, from 1972 until his death in 1987. [Name removed]'s wife sued the companies, alleging that the defendants negligently solicited blood plasma from paid donors who had a high risk of having HIV, failed to determine whether any lots of Factor VIII contained plasma from an at-risk donor, failed to warn consumers of possible risks, and failed to heat-treat HIV and other viruses in Factor VIII, despite industry-wide knowledge of the risk of infection. The three-judge panel said the trial judge's decision to avoid ruling on the antigenic stimulation theory, based on insufficient evidence, was improper. In addition, the appeals court said a retrial is necessary because of improper remarks made by Alpha's attorney.

  6. Compact reversed-field pinch reactors (CRFPR)

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Hagenson, R.L.; Schnurr, N.M.; Copenhaver, C.; Bathke, C.G.; Miller, R.L.; Embrechts, M.J.

    1986-01-01

    The unique confinement properties of the poloidal-field-dominated Reversed-Field Pinch (RFP) are exploited to examine physics and technical issues related to a compact high-power-density fusion reactor. This resistive-coil, steady-state, toroidal device would use a dual-media (i.e., two separate coolants) power cycle that would be driven by a fusion power core (FPC, i.e., plasma chamber, first wall, blanket, shield, and coils) having a power density and mass approaching pressurized-water-fission reactor values. A 1000-MWe(net) base case is selected from a comprehensive trade-off study to examine technological issues related to operating a high-power-density FPC. A general rationale outlining the need for improved fusion concepts is given, followed by a description of the RFP principle, a detailed systems and trade-off analysis, and a conceptual FPC design for the ∝ 20-MW/m 2 (neutrons) compact RFP reactor, CRFPR(20). Key FPC components are quantified, and full power-balance, thermal, and mechanical FPC integrations are given. (orig.)

  7. A study on reverse osmosis permeating treatment for yarn dyeing ...

    African Journals Online (AJOL)

    This paper presents a fuzzy linear regression model for estimation of reverse osmosis permeating parameters conditions. The proposed model can effectively take on non-crisp, fuzzy and crisp data. This study model used for estimation of reverse osmosis permeating parameters data from Tirupur examines the variables that ...

  8. Using Habit Reversal to Decrease Filled Pauses in Public Speaking

    Science.gov (United States)

    Mancuso, Carolyn; Miltenberger, Raymond G.

    2016-01-01

    This study evaluated the effectiveness of simplified habit reversal in reducing filled pauses that occur during public speaking. Filled pauses consist of "uh," "um," or "er"; clicking sounds; and misuse of the word "like." After baseline, participants received habit reversal training that consisted of…

  9. On reversible Turing machines and their function universality

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Glück, Robert

    2016-01-01

    We provide a treatment of the reversible Turing machines (RTMs) under a strict function semantics. Unlike many existing reversible computation models, we distinguish strictly between computing the function backslashlambda x.f(x) $ x . f ( x ) and computing the function backslashlambda x. (x, f(x)...

  10. Clean energy generation using capacitive electrodes in reverse electrodialysis

    NARCIS (Netherlands)

    Vermaas, David; Bajracharya, S.; Bastos Sales, B.; Saakes, Michel; Hamelers, B.; Nijmeijer, Dorothea C.

    2013-01-01

    Capacitive reverse electrodialysis (CRED) is a newly proposed technology to generate electricity from mixing of salt water and fresh water (salinity gradient energy) by using a membrane pile as in reverse electrodialysis (RED) and capacitive electrodes. The salinity difference between salt water and

  11. Recovery of uranium by a reverse osmosis process

    International Nuclear Information System (INIS)

    Cleary, J.G.; Stana, R.R.

    1980-01-01

    A method for concentrating and recovering uranium material from an aqueous solution, comprises passing a feed solution containing uranium through at least one reverse osmosis membrane system to concentrate the uranium, and then flushing the concentrated uranium solution with water in a reverse osmosis membrane system to further concentrate the uranium

  12. Heuristic Synthesis of Reversible Logic – A Comparative Study

    Directory of Open Access Journals (Sweden)

    Chua Shin Cheng

    2014-01-01

    Full Text Available Reversible logic circuits have been historically motivated by theoretical research in low-power, and recently attracted interest as components of the quantum algorithm, optical computing and nanotechnology. However due to the intrinsic property of reversible logic, traditional irreversible logic design and synthesis methods cannot be carried out. Thus a new set of algorithms are developed correctly to synthesize reversible logic circuit. This paper presents a comprehensive literature review with comparative study on heuristic based reversible logic synthesis. It reviews a range of heuristic based reversible logic synthesis techniques reported by researchers (BDD-based, cycle-based, search-based, non-search-based, rule-based, transformation-based, and ESOP-based. All techniques are described in detail and summarized in a table based on their features, limitation, library used and their consideration metric. Benchmark comparison of gate count and quantum cost are analysed for each synthesis technique. Comparing the synthesis algorithm outputs over the years, it can be observed that different approach has been used for the synthesis of reversible circuit. However, the improvements are not significant. Quantum cost and gate count has improved over the years, but arguments and debates are still on certain issues such as the issue of garbage outputs that remain the same. This paper provides the information of all heuristic based synthesis of reversible logic method proposed over the years. All techniques are explained in detail and thus informative for new reversible logic researchers and bridging the knowledge gap in this area.

  13. Paleomagnetic Study of a Reversal of the Earth's Magnetic Field.

    Science.gov (United States)

    Dunn, J R; Fuller, M; Ito, H; Schmidt, V A

    1971-05-21

    A detailed record of a field reversal has been obtained from the natural remanent magnetization of the Tatoosh intrusion in Mount Rainier National Park, Washington. The reversal took place at 14.7 +/- 1 million years and is interpreted to be from reverse to normal. A decrease in the intensity of the field of about an order of magnitude occurs immediately before the reversal, while its orientation remains substantially unchanged. The onset of the reversal is marked by abrupt swinging of the virtual geomagnetic pole along an arc of a great circle. During the reversal the pole traces a path across the Pacific. In the last stage of the process recorded in the sections, the succession of virtual geomagnetic poles is very similar to those generated by secular variation in the recent past. Although the cooling rate of the intrusion is not sufficiently well known to permit a useful calculation of the duration of the reversal process, an estimate based on the length of the supposed secular variation cycles gives 1 to 4 x 103 years for the reversal of field direction and approximately 1 x 104 years for the time scale of the intensity changes.

  14. Tests of time reversal in neutron-nucleus scattering

    International Nuclear Information System (INIS)

    Bowman, J.D.

    1988-01-01

    Experiments to test time-reversal invariance are discussed. The experiments are based on observables constructed from the momentum and spin vectors of epithermal neutrons and from the spin of an aligned or polarized target. It is shown that the proposed tests are detailed balance tests of time-reversal invariance. The status of the experiments is briefly reviewed. 14 refs., 5 figs

  15. An Exploratory Analysis of Reverse Logistics in Flanders

    NARCIS (Netherlands)

    Verstrepen, Sven; Cruijssen, Frans; Brito, Marisa P De; Dullaert, Wout

    2007-01-01

    This paper reports on a reverse logistics survey of shippers and logistics service providers in Flanders, one of the leading logistics regions in Europe. We characterise the reverse logistics activities with respect to return reasons, recovery options, outsourcing, lifecycle length and value of

  16. Contribution of the reverse endoprosthesis to glenohumeral kinematics.

    NARCIS (Netherlands)

    Bergmann, J.H.M.; de Leeuw, M.; Janssen, T.W.J.; Veeger, H.E.J.; Willems, W.J.

    2008-01-01

    After placement of a reverse shoulder endoprosthesis, range of motion is usually still compromised. To what extent this occurs from limitation in motion of the reverse endoprosthesis is, however, unclear. We measured the motion pattern of 16 patients (18 shoulders) during three active and passive

  17. Vasectomy as a reversible form of contraception for select patients.

    Science.gov (United States)

    Samplaski, Mary K; Daniel, Ariande; Jarvi, Keith

    2014-04-01

    To provide an effective form of birth control, men may choose a reversible or permanent form of contraception. Vasectomy is presently offered as a permanent option for male contraception. We have had patients who were interested in vasectomy and reversal as a temporary birth control option. The purpose of this paper is to determine if vasectomy should be offered for selected couples as a temporary form of contraception and under which circumstances. A literature review was conducted to determine the available reversible contraceptive options, risks, failure rates and contraindications to each, and the risks and success rates of vasectomy and vasectomy reversal. Reversible contraceptives include hormonally based methods for women, non-hormonal anatomic barrier devices and spermatocidal agents. Hormone based therapies may be contraindicated in women with cardiovascular disease, hypertension, and some cancers. Non-hormonal contraceptives are generally less effective and may be unacceptable for some couples due to higher failure rates, difficulty of use and lack of acceptance. Both vasectomy and vasectomy reversal are low risk procedures. Reversal may be performed with a high degree of success, particularly with a short obstructive interval (97% patency if performed form of sterilization for most couples, there are select couples, unable or unwilling to use other forms of birth control, who would benefit from an informed discussion about using a vasectomy as a reversible form of contraception.

  18. Hidden Randomness between Fitness Landscapes Limits Reverse Evolution

    Science.gov (United States)

    Tan, Longzhi; Serene, Stephen; Xiao Chao, Hui; Gore, Jeff

    2012-02-01

    Natural populations must constantly adapt to the ever-changing environment. A fundamental question in evolutionary biology is whether adaptations can be reversed by returning the population to its ancestral environment. Traditionally, reverse evolution is defined as restoring an ancestral phenotype (physical characteristics such as body size), and the classic Dollo's Law has hypothesized the impossibility of reversing complex adaptations. However, this ``law'' remains ambiguous unless reverse evolution can be studied at the level of genotypes (the underlying genome sequence). We measured the fitness landscapes of a bacterial antibiotic-resistance gene and analyzed the reversibility of evolution as a global, statistical feature of the landscapes. In both experiments and simulations, we find that an adaptation's reversibility declines as the number of mutations it involves increases, suggesting a probabilistic form of Dollo's Law at the molecular level. We also show computationally that slowly switching between environments facilitates reverse evolution in small populations, where clonal interference is negligible or moderate. This is an analogy to thermodynamics, where the reversibility of a physical process is maximized when conditions are modified infinitely slowly.

  19. Montessori and Steiner: A Pattern of Reverse Symmetries.

    Science.gov (United States)

    Coulter, Dee Joy

    2003-01-01

    Explains the educational movements precipitated by Maria Montessori and Rudolf Steiner as comprising a pattern of reverse symmetries. Notes the influence of war on their philosophies. Discusses reverse symmetries in curriculum related to mathematics, geography, and history. Maintains that each of these two movements holds the other at its core,…

  20. Reversible polymer networks containing covalent and hydrogen bonding interactions

    NARCIS (Netherlands)

    Araya-Hermosilla, R.; Broekhuis, A.A.; Picchioni, F.

    Thermally reversible polymers with relatively high glass transition temperatures (T-g) are difficult to prepare but very interesting from an application point of view. In this work we present a novel reversible thermoset with tunable T-g based on chemical modification of aliphatic polyketones (PM)