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Sample records for matthieu wipliez ghislain

  1. Matthieu Cattin (1982 - 2015)

    CERN Multimedia

    2015-01-01

    We deeply regret to announce the death of Matthieu Cattin on 13 April 2015.   Matthieu Cattin, who was born on 22 February 1982, worked in the BE Department and had been at CERN since 1 October 2005.  The Director-General has sent a message of condolence to his family on behalf of the CERN personnel. Social Affairs Human Resources Department The CERN Ski Club has expressed their condolences for the loss of Matthieu Cattin in an Echo article.

  2. Matthieu Cattin (1982 - 2015) - Hervé Milcent (1965 - 2015)

    CERN Multimedia

    2015-01-01

    Hervé Milcent and Matthieu Cattin lost their lives in an avalanche in the Becs de Bosson area of Valais, Switzerland, on Sunday, 12 April. These two mountain sport enthusiasts were clearly very dear to many people, including all those who came to say a final farewell at their funerals, in Thoiry (the Ain) and Breuleux (Jura) respectively.     Hervé Milcent. Hervé arrived at CERN in 1988 under the coopérant scheme (professional work in lieu of French military service) to work on data acquisition systems for the LEP detectors, and was recruited as a staff member in 1996 in the Controls (ECP) group, which later became IT-CO, to work on the control systems for ALICE. Then he joined the LHC-IAS group and was awarded an indefinite contract. Many of the LHC’s monitoring systems owe much of their success to Hervé, who worked assiduously to test and check everything to ensure that all the systems worked from the moment they we...

  3. Lydon, Ghislaine — On Trans-Saharan Trails: Islamic Law, Trade Networks, and Cross-Cultural Exchange in Nineteenth-Century Western Africa

    Directory of Open Access Journals (Sweden)

    Judith Scheele

    2013-06-01

    Full Text Available Le livre de Ghislaine Lydon ouvre un nouveau chapitre dans les recherches historiques sur le Sahara. L’auteure reprend certes un sujet classique : le commerce transsaharien. Mais elle l’étudie à partir de sources locales qui, malgré leur richesse et leur abondance, n’ont jusqu’ici que trop peu attiré l’intérêt des chercheurs des universités occidentales – à l’exception de quelques travaux isolés tels ceux de Paul Pascon au Maroc, d’Ulrich Haarmann en Libye, ou de Rainer Osswald en Mauritanie....

  4. Saint-Etienne'i disainibiennaal 2007

    Index Scriptorium Estoniae

    2007-01-01

    Lõuna-Prantsusmaal toimunud disainiüritusest. Pikemalt disainerite Marie-Laure Bourgeois ja Vincent Becheau tänavaistmetest Foneemid (ehk Häälikud) ja Matthieu Lehanneur'i projektist "Viis elementi"

  5. Calcifications valvulaires chez l'hémodialysé au Maroc | Faqih | Pan ...

    African Journals Online (AJOL)

    Calcifications valvulaires chez l'hémodialysé au Maroc. Samia Ait Faqih, Béfa Noto-Kadou-Kaza, Lalla Meryam Abouamrane, Naoufal Mtiou, Selma El Khaya, Mohamed Zamd, Ghislaine Medkouri, Mohamed Gharbi Bengahanem, Benyounes Ramdani ...

  6. Reference: 275 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available |Bhatt Anuj M|Chelysheva Liudmila|Diallo Stéphanie|Gendrot Ghislaine|Grelon Mathilde|Horlow Christine|Mercie...r Raphaël|Márquez-Lema Angustias|Mézard Christine|Rocques Nathalie|Vezon Daniel|Vrielynck Nathalie

  7. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Male-limited evolution suggests no extant intralocus sexual conflict over the sexually dimorphic cuticular hydrocarbons of Drosophila melanogaster · Stéphanie Bedhomme Adam K. Chippindale N. G. Prasad Matthieu Delcourt Jessica K. Abbott Martin A. Mallet Howard D. Rundle · More Details Abstract Fulltext PDF.

  8. 2170-IJBCS-Aticle-Kougoum Pienbeng Ghislain Noé

    African Journals Online (AJOL)

    hp

    Ploceus cucullatus) dans la ville de Dschang et de ses environs, ainsi que sur les risques potentiels de transmission de leurs germes à l'homme et aux autres animaux. A cet effet, un total de 65 oiseaux ont été capturés et examinés pour la.

  9. Etude sur le Latin dus codex Bobiensis (k) des evangiles

    NARCIS (Netherlands)

    Hoogterp, Pieter Willem

    1930-01-01

    Le manuscrit dus texte, dont nous allons entreprendre l'étude, se trouve à la Biblioteca Nazionale de Turin (G VII 15). Il est universellement connu sous le nom de Codex Bobiensis (k d'après Tischendorf) et contient des parties de l'évangile selon S. Matthieu (I, 1-III, 10; IV, 2-XIV, 17; XV, 20-36)

  10. Adhesive Micropatterns for Cells: A Microcontact Printing Protocol

    OpenAIRE

    sprotocols

    2014-01-01

    Authors: Manuel Théry and Matthieu Piel Corresponding authors ([](); []()) ### INTRODUCTION This protocol describes a simple, fast, and efficient method for making adhesive micropatterns that can be used to control individual cell shape and adhesion patterns. It is based on the use of an elastomeric stamp containing microfeatures to print proteins on the substrate of choice. The process can be subdiv...

  11. Micropatterning on glass with deep UV

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Nicolas CARPI, Matthieu PIEL, Ammar Azioune & Jenny Fink ### Abstract This protocol describes a method to print micropatterns on glass with extra-cellular matrix proteins to promote cell adhesion. The non-adhesive part is made with polylysine grafted polyethyleneglycol (PLL-g-PEG). This technique is reproducible, cheap, fast and can achieve high resolution (~1 µm). ### Introduction This protocol explains how to make high resolution adhesive micropattens of protein...

  12. CERN collect for Earthquakein Italy August 24, 2016

    CERN Multimedia

    Brice, Maximilien

    2016-01-01

    Ghislain Roy, President of CERN's Staff Association, Maurizio Serra, Ambassador, permanent Mission of Italy to teh United NAtions Office in Geneva, FAbiola Gianotti, CERN director General and Umberto Dosselli, scientific ataché Italian Permanent Mission in Geneva, show the letter co-signed by CERN's director general and CERN' s Staff Association President indicating the amounbt collected in favour of the vicitims of the August 24 2016 earthquake in central Italy.

  13. Facial skin pores: a multiethnic study

    OpenAIRE

    Flament, Frederic; Francois,Ghislain; Qiu,Huixia; Ye,Chengda; Hanaya,Tomoo; Batisse,Dominique; Cointereau-Chardon,Suzy; Seixas,Mirela Donato Gianeti; Dal Belo,Susi Elaine; Bazin,Roland

    2015-01-01

    Frederic Flament,1 Ghislain Francois,1 Huixia Qiu,2 Chengda Ye,2 Tomoo Hanaya,3 Dominique Batisse,3 Suzy Cointereau-Chardon,1 Mirela Donato Gianeti Seixas,4 Susi Elaine Dal Belo,4 Roland Bazin5 1Department of Applied Research and Development, L’Oreal Research and Innovation, Paris, France; 2Department of Applied Research and Development, L’Oreal Research and Innovation, Shanghai, People’s Republic of China; 3Department of Applied Research and Development, L&r...

  14. Estonie 2000-2001 : La fin des consensus politiques? / Celine Bayou, Matthieu Chillaud

    Index Scriptorium Estoniae

    Bayou, Celine

    2001-01-01

    Ülevaade Eesti poliitikast ja majandusest aastal 2000-2001. Tabelid: Eesti majandusnäitajad 1993-2000; poliitiliste sündmuste kronoloogia 2000-2001 mai; Eesti erakonnad; valitsuse koosseis juuni 2001

  15. Crédit des illustrations

    OpenAIRE

    2017-01-01

    Illustration de couverture : Lyon, cathédrale Saint-Jean, culée de l’arc-boutant 2/3 : David (XIIIe siècle) surgissant de l’échafaudage (XXIe siècle). Photo Jean-Pierre Gobillot. Illustration de la quatrième de couverture : Lyon, cathédrale Saint-Jean, arcature extérieure de l’abside, chapiteau central. Dessin Ghislaine Macabéo. Photos Jean-Pierre Gobillot : fig. 1, 2, 10, 13, 14, 16, 23, 28, 29, 34, 35, 36, 37, 40, 41, 46, 54, 55, 56, 59, 60, 67, 76a, 78, 80, 82, 83, 88, 90, 97, 105, 106, 11...

  16. Election of the new Executive Committee: Combining continuity and renewal

    CERN Multimedia

    Staff Association

    2015-01-01

    In agreement with the Staff Association’s Statutes the new Staff Council elected on Tuesday, 8 December, a new President and his Executive Committee for a two-year mandate 2016–2017. Alessandro Raimondo, the only candidate for president, presented a list of delegates for an Executive Committee, which combines continuity and renewal. These are important assets to start working in early 2016 on the implementation of the decisions of the 2015 Five-Yearly Review, especially in the field of the career structure. Alessandro RAIMONDO GS President / Président Céline GROBON PH Vice-president / Vice-président Catherine LAVERRIÈRE DGS Vice-president / Vice-président Juan GARCIA PEREZ TE Treasurer / Trésorier Ghislain ROY BE Secretary / Secrétaire Sandrine BAUDAT FP Member / Membre Oliver BOETTCHER EN Member / Membre Rachel BRAY GS Member / Membre Nicolas DELRUELLE TE Member / Membre Gianni DEROMA GS Mem...

  17. THEOLOGIE CHRETIENNE ORTODOXE ET SECURITE SOCIALE QUELQUES CONSIDERATIONS SUR LA LIBERTE EN AMOUR ET DE L’IMPERATIF DE LA CHARITE

    Directory of Open Access Journals (Sweden)

    Stelian MANOLACHE

    2016-12-01

    Full Text Available With the message of Jesus Christ, ’For I was hungry and you gave me to eat; I was thirsty and you gave me drink ... Then the righteous will answer: Lord, when did we see you hungry and we fed You? Or thirsty and we gave you drink? And the king, shall say unto them, Verly I say unto you, as you did it to one of these brothers of mine, you have done it unto me (Matthieu 25, 35-401’’, and founding the Church visibly at Pentecost, one of the constant work of the Christian Church was and is her revelation to the world of philanthropy and our neighbor. In this study, we will try to explore some of the main theoretical resorts, of the Catholic social action, respectively to decipher what, in the late period of the Western world, but also the Oreintal world, came together in the social doctrine of Ecclesia, starting from their own social thinking concepts.

  18. Fellow’s Apero

    CERN Multimedia

    Staff Association

    2017-01-01

    February 21st marked the happening of the first Fellow's Apero, an event organised by the Staff Association for the CERN Fellows. At the end of the day, about 300 of the over 700 Fellows gathered in Restaurant 1. They came to meet each other, meet the Staff Association Bureau and delegates, share experience, and get some useful information from the event speakers. The turnout of the Fellows was a pleasant surprise, filling the entire space allocated at Restaurant 1 and digging bravely into the prepared snacks. Staff Association - Fellow's Apero - 21st February 2017 The Staff Association president, Ghislain Roy, welcomed our guests. Barbora Gulejova, a Fellow and Staff Association delegate, then gave information on what the Staff Association can do for Fellows, and how they can get involved. Jiri Kral, also a Fellow and Staff Association delegate, presented Fellow-centred statistics and information on personal development opportunities. We also had the great pleasure that Katharine Thomas-C...

  19. Theater

    CERN Multimedia

    Staff Association

    2011-01-01

    LES TERRIENS texte et mise en scène de Claire Rengade Un spectacle inspiré de la vie du CERN ! Depuis deux ans, Claire Rengade et son équipe sont en chantier de leur prochaine création, Les Terriens, texte né d'un vagabondage au CERN (Centre Européen de Recherche Nucléaire). Omnubilée par la parole, elle propose une recherche singulière et passionnée, une forme très novatrice entre théâtre, poésie et reportage. Après une rencontre avec divers scientifiques du CERN (Ghislain Roy, Jean-Pierre Quesnel, Vincent Baglin...), Claire Rengade invente une "machine-à-regarder-comment-le-monde-est-fait". Sur fond d'accélérateur de particules, le résultat n'est pas un documentaire, c'est une fiction. Une boîte à expérimenter par l...

  20. Optimal diagnosis, prevention, and management of periprosthetic joint infection

    Directory of Open Access Journals (Sweden)

    Tafer N

    2015-01-01

    Full Text Available Nathalie Tafer,1 Wilson Belaieff,1 Céline Cuérel,1 Matthieu Zingg,1 Pierre Hoffmeyer,1 Ilker Uçkay1,2 1Orthopedic Surgery Department, 2Division of Infectious Diseases, University of Geneva Hospitals and Medical School, Geneva, Switzerland Abstract: The pace of the aging population is steadily rising worldwide with a parallel increase in the demand for joint replacement procedures. With the increasing number of patients undergoing arthroplasty, there is also an increased risk for arthroplasty infection that may lead to severe complications, poorer outcome, and substantial extra costs for health care systems. Current rates of prosthetic joint infection are not dramatically different from the 1960s or 1970s, but some general principles are now better defined, and their management has been studied extensively during the past decades, thus resulting in a change in clinical practice. The purpose of this review is to summarize important principles of prosthetic joint infection to guide the clinician and to contribute to the optimal diagnosis, prevention, and management of periprosthetic joint infections. Keywords: arthroplasty infection, antibiotic therapy, biofilm, surgery, prevention

  1. The CERN Relay Race: A Runaway Success!

    CERN Multimedia

    Staff Association

    2018-01-01

    24th May saw the traditional Relay Race take place at CERN, organised jointly by the Running Club and the CERN Staff Association. In 2018, the Relay Race lived up to expectations with a record number of participants, with no fewer than 848 entries across different categories! In total 135 teams of 6 runners and 38 walkers completed the course on the Meyrin site in beautiful sunshine. Congratulations to all those who took part! Ghislain Roy, President of the Staff Association, fired the starting pistol for the first batch of runners, which included a team from the Directorate, with the Director General also taking part. Demonstrating interest in this event at the highest level of the Organization. Thank you for this much-appreciated commitment! Also a number of very high-level runners brought added excitement to the 2018 edition. The 1000-meter men’s race was won by Marcin Patecki from the CERN Running Club in 2’40, just in front of Baptiste Fieux from the Berthie Sport team who came in at...

  2. Tragic loss at CERN

    CERN Multimedia

    CERN Ski Club

    2015-01-01

    Tragic loss at CERN The CERN community is mourning the tragic loss of two members of the CERN Ski Club. On Sunday, April 12, an avalanche buried four out of five skiers, taking part in a ski touring in the region of the Becs de Bosson in Valais (CH). The fifth skier, who had not been buried in the snow,  courageously managed to save two of the skiers, but Hervé Milcent, 49 years, federal ski instructor, and Mattieu Cattin, 33 years, were buried under two to three meters of snow, far down the avalanche slope, and did not survive, despite the fast arrival of the mountain rescue. In its 40 years of existence, the CERN Ski Club, one of the biggest in the Geneva area, has never been confronted with such a tragedy. The passing of Hervé and Matthieu has deeply shocked and saddened all volunteers of the Club as well as the entire alpine community. The ski touring section of the club would like to honour its friend Hervé, who joined the club in 1998. In 2003 he became res...

  3. Geological problems in radioactive waste isolation

    International Nuclear Information System (INIS)

    Witherspoon, P.A.

    1991-01-01

    The problem of isolating radioactive wastes from the biosphere presents specialists in the fields of earth sciences with some of the most complicated problems they have ever encountered. This is especially true for high level waste (HLW) which must be isolated in the underground and away from the biosphere for thousands of years. Essentially every country that is generating electricity in nuclear power plants is faced with the problem of isolating the radioactive wastes that are produced. The general consensus is that this can be accomplished by selecting an appropriate geologic setting and carefully designing the rock repository. Much new technology is being developed to solve the problems that have been raised and there is a continuing need to publish the results of new developments for the benefit of all concerned. The 28th International Geologic Congress that was held July 9--19, 1989 in Washington, DC provided an opportunity for earth scientists to gather for detailed discussions on these problems. Workshop W3B on the subject, ''Geological Problems in Radioactive Waste Isolation -- A World Wide Review'' was organized by Paul A Witherspoon and Ghislain de Marsily and convened July 15--16, 1989 Reports from 19 countries have been gathered for this publication. Individual papers have been cataloged separately

  4. Geological problems in radioactive waste isolation

    Energy Technology Data Exchange (ETDEWEB)

    Witherspoon, P.A. (ed.)

    1991-01-01

    The problem of isolating radioactive wastes from the biosphere presents specialists in the fields of earth sciences with some of the most complicated problems they have ever encountered. This is especially true for high level waste (HLW) which must be isolated in the underground and away from the biosphere for thousands of years. Essentially every country that is generating electricity in nuclear power plants is faced with the problem of isolating the radioactive wastes that are produced. The general consensus is that this can be accomplished by selecting an appropriate geologic setting and carefully designing the rock repository. Much new technology is being developed to solve the problems that have been raised and there is a continuing need to publish the results of new developments for the benefit of all concerned. The 28th International Geologic Congress that was held July 9--19, 1989 in Washington, DC provided an opportunity for earth scientists to gather for detailed discussions on these problems. Workshop W3B on the subject, Geological Problems in Radioactive Waste Isolation -- A World Wide Review'' was organized by Paul A Witherspoon and Ghislain de Marsily and convened July 15--16, 1989 Reports from 19 countries have been gathered for this publication. Individual papers have been cataloged separately.

  5. Manifesto for De-carbonizing Europe

    International Nuclear Information System (INIS)

    2017-01-01

    A month before the first round of the French presidential elections, on 21 March in Paris, the Shift Project, a think-tank on energy transition headed by Matthieu Auzanneau, presented a Manifesto for De-carbonizing Europe. The manifesto, signed in late March by more than 2,500 people - the majority being directors of companies of all sizes and professional organizations, though many are personalities from the French academic world - calls on European states 'to introduce policies capable, by 2050, of reducing greenhouse gas emissions as near as possible to zero'. It also effectively invites candidates in the presidential elections to commit to this course of action. Beyond the borders of France, at a time when President Donald Trump is sending out more than troubling signals to the rest of the world regarding US involvement in the campaign against climate change, the initiative has the virtue of encouraging European states to take a clearly proactive stance on their commitments to the Paris Agreement of late 2015. That proactive attitude is essential to preserve our planet's climate and limit the disruption future generations will have to face. It is also an important signal to the other signatories of the Paris Agreement to honour the commitments made. This is why Futuribles has taken the decision to carry this manifesto for its readers. (authors)

  6. Acquired resistance of malarial parasites against artemisinin-based drugs: social and economic impacts

    Directory of Open Access Journals (Sweden)

    Johanna M Porter-Kelley

    2010-08-01

    Full Text Available Johanna M Porter-Kelley1, Joann Cofie2, Sophonie Jean2, Mark E Brooks1, Mia Lassiter1, DC Ghislaine Mayer21Life Sciences Department, ­Winston-Salem State University, Winston Salem, NC, USA; 2Department of Biology, Virginia Commonwealth University, Richmond, VA, USAAbstract: Malaria, a disease of poverty and high morbidity and mortality in the tropical world, has led to a worldwide search for control measures. To that end, good antimalarial chemotherapies have been difficult to find in the global market and those that seem to be most effective are rapidly becoming ineffective due to the emergence and spread of drug resistance. Artemisinin, a very effective yet expensive antimalarial, has quickly become the recommended drug of choice when all other possibilities fail. However, for all its promise as the next great antimalarial, the outlook is bleak. Resistance is developing to artemisinin while another effective antimalarial is not in sight. Malaria endemic areas which are mostly in developing countries must deal with the multifaceted process of changing and implementing new national malaria treatment guidelines. This requires complex interactions between several sectors of the affected society which in some cases take place within the context of political instability. Moreover, the cost associated with preventing and containing the spread of antimalarial resistance is detrimental to economic progress. This review addresses the impact of artemisinin resistance on the socioeconomic structure of malaria endemic countries.Keywords: artemisinin-based drugs, social, economic, malarial parasite resistance

  7. Matthieu Gateau, Maud Navarre, Florent Schepens (dir.), Quoi de neuf depuis la parité ? Du genre dans la construction des rôles politiques

    OpenAIRE

    Robinet, Caroline

    2013-01-01

    Depuis les gender et women’s studies, développées aux États-Unis dans les années 1970, la notion de genre est devenue une catégorie analytique à part entière. En profitant à la compréhension des positions, des différences et des relations entre hommes et femmes, elle a également permis de prendre conscience et connaissance qu’à la distinction biologique naturelle s’ajoutent des divergences de genre émanant de nombreuses représentations sociales inspirées de stéréotypes historiquement institué...

  8. L’ange de l’Annonciation, chef de chœur dans Il Vangelo secondo Matteo de Pasolini

    Directory of Open Access Journals (Sweden)

    Sandra Gorgievski

    2012-07-01

    Full Text Available Médiateur par excellence entre le divin et le terrestre, l’ange – et l’épisode biblique de l’Annonciation en particulier, stimulent l’imaginaire contemporain, le mystère de l’incarnation ne pouvant être représenté mais figuré. S’appuyant sur le monde de références du spectateur – des textes source aux thèmes iconographiques médiévaux et renaissants (par exemple Giotto, Fra Angelico, Limbourg, del Cossa, Crivelli, della Francesca, L’Évangile selon saint Matthieu de Pasolini a principalement recours au son. De la musique sacrée (Bach, Misa Luba, Negro Spiritual et profane (Mozart, Prokofiev, Blind Willie Johnson aux chœurs qui fonctionnent comme des voix over, le film fait ‘entendre’ la présence angélique au spectateur. L’hybridité même des codes cinématographiques interroge le statut de l’image, tout en évoquant la présence immanente de l’ange –métaphore de l’indicible et l’inintelligible.Arch-mediator between the divine and the mundane, the angelic icon - and the Biblical episode of the Annunciation in particular - stimulate the contemporary imagination, as the mystery of the incarnation itself cannot be represented, but rather figured. Relying on the viewer’s world of references – from Biblical texts to Medieval and Renaissance iconography (Giotto, Fra Angelico, Limbourg, del Cossa, Crivelli, della Francesca among others, Pasolini also extensively resorts to sound in his Gospel According to St. Matthew. The film seeks to allow the viewer ‘hear’ angels, from sacred music (Bach, Misa Luba, Negro Spiritual, profane music (Mozart, Prokofiev, Blind Willie Johnson to choirs used as voice over. Hybrid cinematic devices question the status of images while they evoke the immanent presence of angels – metaphorically the unspeakable and unintelligible.

  9. Proteomic analysis revealed alterations of the Plasmodium falciparum metabolism following salicylhydroxamic acid exposure

    Directory of Open Access Journals (Sweden)

    Torrentino-Madamet M

    2011-09-01

    Full Text Available Marylin Torrentino-Madamet1, Lionel Almeras2, Christelle Travaillé1, Véronique Sinou1, Matthieu Pophillat3, Maya Belghazi4, Patrick Fourquet3, Yves Jammes5, Daniel Parzy11UMR-MD3, Université de la Méditerranée, Antenne IRBA de Marseille (IMTSSA, Le Pharo, 2Unité de Recherche en Biologie et Epidémiologie Parasitaires, Antenne IRBA de Marseille (IMTSSA, Le Pharo, 3Centre d'Immunologie de Marseille Luminy, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Université de la Méditerranée, 4Centre d'Analyse Protéomique de Marseille, Institut Fédératif de Recherche Jean Roche, Faculté de Médecine Nord, 5UMR-MD2, Physiologie et Physiopathologie en Conditions d'Oxygénations Extrêmes, Institut Fédératif de Recherche Jean Roche, Faculté de Médecine Nord, Marseille, FranceObjectives: Although human respiratory metabolism is characterized by the mitochondrial electron transport chain, some organisms present a “branched respiratory chain.” This branched pathway includes both a classical and an alternative respiratory chain. The latter involves an alternative oxidase. Though the Plasmodium falciparum alternative oxidase is not yet identified, a specific inhibitor of this enzyme, salicylhydroxamic acid (SHAM, showed a drug effect on P. falciparum respiratory function using oxygen consumption measurements. The present study aimed to highlight the metabolic pathways that are affected in P. falciparum following SHAM exposure.Design: A proteomic approach was used to analyze the P. falciparum proteome and determine the metabolic pathways altered following SHAM treatment. To evaluate the SHAM effect on parasite growth, the phenotypic alterations of P. falciparum after SHAM or/and hyperoxia exposure were observed.Results: After SHAM exposure, 26 proteins were significantly deregulated using a fluorescent two dimensional-differential gel electrophoresis. Among these deregulated proteins

  10. In vivo biodistribution and biological impact of injected carbon nanotubes using magnetic resonance techniques

    Directory of Open Access Journals (Sweden)

    Achraf Al Faraj

    2011-02-01

    Full Text Available Achraf Al Faraj1,2, Florence Fauvelle3, Nathalie Luciani4, Ghislaine Lacroix5, Michael Levy4, Yannick Crémillieux1, Emmanuelle Canet-Soulas1Université Lyon1, Créatis-LRMN, Lyon, France; 2King Saud University, College of Applied Medical Sciences, Radiological Sciences Department, Riyadh, Kingdom of Saudi Arabia; 3CRSSA, Biophysique Cellulaire et Moléculaire, Laboratoire de RMN, La Tronche, France; 4Université Paris7-Paris Diderot, Matières et Systèmes Complexes, Paris, France; 5Institut National de l’Environnement et des Risques Industriels, Verneuil-en-Halatte, FranceBackground: Single-walled carbon nanotubes (SWCNT hold promise for applications as contrast agents and target delivery carriers in the field of nanomedicine. When administered in vivo, their biodistribution and pharmacological profile needs to be fully characterized. The tissue distribution of carbon nanotubes and their potential impact on metabolism depend on their shape, coating, and metallic impurities. Because standard radiolabeled or fluorescently-labeled pharmaceuticals are not well suited for long-term in vivo follow-up of carbon nanotubes, alternative methods are required.Methods: In this study, noninvasive in vivo magnetic resonance imaging (MRI investigations combined with high-resolution magic angle spinning (HR-MAS, Raman spectroscopy, iron assays, and histological analysis ex vivo were proposed and applied to assess the biodistribution and biological impact of intravenously injected pristine (raw and purified and functionalized SWCNT in a 2-week longitudinal study. Iron impurities allowed raw detection of SWCNT in vivo by susceptibility-weighted MRI.Results: A transitional accumulation in the spleen and liver was observed by MRI. Raman spectroscopy, iron assays, and histological findings confirmed the MRI readouts. Moreover, no acute toxicological effect on the liver metabolic profile was observed using the HR-MAS technique, as confirmed by quantitative real

  11. Facial skin pores: a multiethnic study

    Directory of Open Access Journals (Sweden)

    Flament F

    2015-02-01

    Full Text Available Frederic Flament,1 Ghislain Francois,1 Huixia Qiu,2 Chengda Ye,2 Tomoo Hanaya,3 Dominique Batisse,3 Suzy Cointereau-Chardon,1 Mirela Donato Gianeti Seixas,4 Susi Elaine Dal Belo,4 Roland Bazin5 1Department of Applied Research and Development, L’Oreal Research and Innovation, Paris, France; 2Department of Applied Research and Development, L’Oreal Research and Innovation, Shanghai, People’s Republic of China; 3Department of Applied Research and Development, L’Oreal Research and Innovation, Tokyo, Japan; 4Department of Applied Research and Development, L’Oreal Research and Innovation, Rio de Janeiro, Brazil; 5RB Consult, Bievres, France Abstract: Skin pores (SP, as they are called by laymen, are common and benign features mostly located on the face (nose, cheeks, etc that generate many aesthetic concerns or complaints. Despite the prevalence of skin pores, related literature is scarce. With the aim of describing the prevalence of skin pores and anatomic features among ethnic groups, a dermatoscopic instrument, using polarized lighting, coupled to a digital camera recorded the major features of skin pores (size, density, coverage on the cheeks of 2,585 women in different countries and continents. A detection threshold of 250 µm, correlated to clinical scorings by experts, was input into a specific software to further allow for automatic counting of the SP density (N/cm2 and determination of their respective sizes in mm2. Integrating both criteria also led to establishing the relative part of the skin surface (as a percentage that is actually covered by SP on cheeks. The results showed that the values of respective sizes, densities, and skin coverage: 1 were recorded in all studied subjects; 2 varied greatly with ethnicity; 3 plateaued with age in most cases; and 4 globally reflected self-assessment by subjects, in particular those who self-declare having “enlarged pores” like Brazilian women. Inversely, Chinese women were clearly

  12. Laboratory and numerical simulation of internal wave attractors and their instability.

    Science.gov (United States)

    Brouzet, Christophe; Dauxois, Thierry; Ermanyuk, Evgeny; Joubaud, Sylvain; Sibgatullin, Ilias

    2015-04-01

    .-P. A., Geometric focusing of internal waves. J. Fluid Mech, 1995,. 300, 1-41 L. R. M. Maas, D. Benielli, J. Sommeria, and F.-P. A. Lam, Nature (London) 388, 557 (1997). 2. Dauxois, Thierry; Young, W., Journal of Fluid Mechanics, 1999, vol. 390, Issue 01, p.271-295 3. Grisouard, N., Staquet, C., Pairaud, I., 2008, Journal of Fluid Mechanics, 614, 1 4. Scolan, H., Ermanyuk, E., Dauxois, T., 2013, Physical Review Letters, 110, 234501 5. Mercier, Matthieu J.; Garnier, Nicolas B.; Dauxois, Thierry Reflection and diffraction of internal waves analyzed with the Hilbert transform Physics of Fluids, Volume 20, Issue 8, pp. 086601-086601-10 (2008).

  13. New insights from direct monitoring of turbidity currents; and a proposal for co-ordinating international efforts at a series of global "turbidity current test sites"

    Science.gov (United States)

    Talling, Peter

    2015-04-01

    monitoring. This 'test site' initiative may be timely and feasible, due to recent technological advances in monitoring sensors, moorings and autonomous data recovery. This will be illustrated here by seminal field datasets recent collected by colleagues from the Squamish River Delta, Bute Inlet, Monterey Canyon, Congo Canyon and offshore SE Taiwan. This talk will conclude with some suggestions for appropriate test sites and collaborative approaches to future data collection. The initial phase of this proposal has been funded by the UK research councils, and input is sought into the design of the broader test site initiative. Acknowledgements: This overview is based on a seminal body of recent flow monitoring work by international colleagues including John Hughes Clarke, Maria Azpiroz, Matthieu Cartigny, Michael Clare, Cortis Cooper, Stephanie Girardclos, Philip Hill, Gwynn Lintern, James Liu, Andrew Lin, Dan Parsons, Charlie Paull, Cooper Stacey, Esther Sumner, and Jingping Xu, amongst others.

  14. Managing our Nuclear Waste: Choosing Safety and Sustainable Development. Proceedings of the European Forum 2005

    International Nuclear Information System (INIS)

    Fischer, Claude; SCHNEITER, Jean-Louis; Lamoureux, Francois; ); Haug, Peter; Flueler, Thomas; Bouzon, Jean-Luc; Carlsson, Torsten; DEMET, Michel; Marsily, Ghislain de; Gadbois, Serge; Gatignol, Claude; Hooft, Evelyn; Jordan Cizelj, Romana; Rollinger, Francois; Bataille, Christian; Shaver, Kathryn; Linkohr, Rolf; Castellan, Angelo; Collard, Daniel; Devezeaux, Jean-Guy; Dose, Francois; Dupraz, Bernard; Gonnot, Francois-Michel; Leclere, Robert; Pradel, Philippe; Webster, Simon; ); Herzog, Philippe

    2005-01-01

    Since 2003, the 'Entretiens europeens' have engaged a dialogue between stakeholders of various socio-professional backgrounds from several countries and with the European Commission, in order to compare the selected options of management and to emphasize the best experiments, which could inspire an innovating European policy in the world. This third edition is intended to provide an updated State-of-play of the reflexions on these issues. These proceedings are organized as follows: 1 - opening talk: Claude Fischer, Head of Entretiens europeens and Jean-Louis Schneiter, Mayor of Reims. 2 - Audition: Francois Lamoureux, Head of DGTREN, European Commission. 3 - First round table 'Democratic issues, various form of consultation and the involvement of the general public in projects' (Chairman: Dr Peter Haug, Head of FORATOM). The idea here is to look at the various forms of information and consultation provided for the general public. We do not want to look at it as opponents do, based on the acceptance or refusal of a laboratory or a disposal site; we want to consider the progress made in research and the actual contracts of agreed objectives, in line with what has been done in Canada. We would then like to reconsider the rights and responsibilities of citizens. A number of questions will be looked at in detail: - a new culture in social relations with regard to information, consultation and assessment: what are the rights, powers and duties of citizens and stakeholders? - legislative process, public debate, right of veto, referendum, opinion poll etc. How do our neighbours tackle the issue? - the involvement of the general public in contracts of agreed objectives - a prerequisite for their success. Intervention: Thomas Flueler, Ecole Polytechnique federale de Zurich (CH) Participants: Jean-Luc Bouzon, General Council of Haute-Marne, vice-president of AEMHM, Torsten Carlsson, former mayor of Oskarshamn, member of KASAM, Sweden, Michel Demet, ANCLI, Ghislain de Marsily

  15. Mathieu de la Porte e a Ciência dos negociantes (1704 = Mathieu de la Porte and the book La Science des Negocians, 1704

    Directory of Open Access Journals (Sweden)

    Hernâni O. Carqueja

    2011-12-01

    , destacan, entre otras cosas, la prolongada serie de ediciones de este libro, la claridad y esquematización de su exposición, la presentación de libros de contabilidad o la clarificación de los procedimientos para el cierre y la reapertura de cuentas y, en particular su contribución a la clasificación y a la ordenación de las cuentas.These notes are based on the survey of the observations of accredited authors and on the analysis of the book “LA SCIENCE DES NEGOCIANS ET TENEURS DE LIVRES, ou Instruction GENERALE pour ce qui se pratique dans les Comptoirs des Negocians, tant pour les affaires de Banque, que pour les Marchandises; & chez les Financiers pour les Comptes”. The first edition of this book in French was in 1704, and then it had reprints and reeditions until after 1800. The defined task is to explain the contribution of Mathieu de la Porte for the improvement and spread of the doubled entries and, especially, to register the influence in Portugal, and the borrowing of several pages in “Tratado sobre as Partidas Dobradas”, in Portuguese, edited in Turim, 1764. The influence of this author in Spain, France, and in the Italian Peninsula, is recognized respectively by Hernández Esteve (1996:548 by Anne Fortin (1998:259 and Vlaemminck (1956:131 to 132. In the accounting literature, in not Latin languages, it is not so emphatic the recognition of the influence of Matthieu de la Porte, though it is recognized, for example, in Germany by Dieter Schneider (1998: 278. The publication, in Portugal, of the “Guia de Negociantes ou Novo Tratado sobre os Livros de Contas em Partidas Dobradas”, in 1794, which is a translation of a previous book of “Mr. De la Porte” with the first publication in 1685; the quotation, a reference to justify the authorization of publication of the “Mercador Exacto” of João Baptista Bonavie, of an edition, in 1741, of “Mr. De la Porte”; the fact that many paragraphs of the “Tratado sobre as Partidas Dobradas

  16. Obituary: Robert Mowbray Walker, 1929-2004

    Science.gov (United States)

    Schoenherr, Neil T.

    2004-12-01

    Robert M. Walker, PhD, Professor of Physics in Arts & Sciences and a faculty fellow of the McDonnell Center for the Space Sciences, died of stomach cancer Thursday, 12 February 2004, in Brussels, Belgium. He was 75. Walker worked on the frontiers of space research for more than four decades. Robert Walker was born in Philadelphia on 6 February 1929. His mother was Dorothy Potter and he considered Roger Potter his father though he was not his biological father. His early years were spent in New York City and in upstate New York. He attended the Bronx High School of Science, earned his BS in physics from Union College and in 1954, he received his PhD in particle physics from Yale University. He subsequently joined the General Electric Laboratory in Schenectady, New York where he studied the radiation effects in solids. His work on defects in irradiated copper is still regarded as the definitive work on the topic. In the early 1960s, Walker's discovery of fossil nuclear particle tracks in minerals was instrumental to new developments in geo-chronology and cosmic ray physics. In particular, his discovery of tracks from nuclei heavier than iron opened a new frontier of cosmic ray physics. He subsequently pioneered the use of plastics to detect and count such nuclei in cosmic ray balloon flights. Beginning in 1966, when he moved to Washington University and became the first McDonnell Professor of Physics, his research interests turned more toward space physics. He was the inaugural director of the McDonnell Center, which was established in 1975 by a gift from aerospace pioneer James S. McDonnell. Walker was a member of the NASA committee that allocated samples of the first returned lunar materials, and his laboratory led the way in deciphering their record of lunar, solar system and galactic evolution. Together with Ghislaine Crozaz and other colleagues, Walker made path breaking laboratory studies of the first moon rocks revealing the history of solar radiation and