[Influences of Confucianism, Taoism and Buddhism on Chinese Medical Formulas in Jin-Tang Dynasties].

Science.gov (United States)

Wu, Xiao-xiang

2006-04-01

In the Jin-Tang Dynasties, when Confucianism, Taoism and Buddhism contended, conflicted and well blent, forming a state of mingled thoughts of the three sects. It exerted profound influences on Chinese Medical Formulas and promoted the academic fashion of compiling books about medical formulas characterized by collecting various formulas especially the simple and proved recipes. This plays a role in the formation of the formulas used in the Jin-Tang Dynasties, featuring simplicity, convenience, cheapness, and effectiveness, different from those of other periods.

Water footprint of Jing-Jin-Ji urban agglomeration in China

Science.gov (United States)

Zhao, D.

2017-12-01

A rapidly expanding economy and increasing water demand for economic production is placing enormous stress on water quantity and aquatic environment in Northern China, especially the so-called Jing-Jin-Ji (Beijing-Tianjin-Hebei) urban agglomeration. Several studies have focused on energy consumption, air pollution, CO2 emissions and regional blue water footprint (WF) following release of the Jing-Jin-Ji Integration Strategy by the China government. However, a comprehensive assessment distinguishing blue, green and grey WF amongst different industrial sectors, ascertaining how WF transfers internally and beyond the region and final demand consumption is not available. In this study, we quantified the WF and virtual water flow on a sectoral basis for the year 2010 through coupling the multi-regional input-output model (MRIO) with WF assessment. The results showed that Beijing and Tianjin are net importers of green, blue and grey water from Hebei and other provinces to support their needs. Conversely, Hebei exports all WF colors to Beijing, Tianjin and other provinces in China, more than 60% of WF is transferred as virtual water. For the overall Jing-Jin-Ji region a small amount of blue water (2,086 million m3) is exported, but huge amounts of green water (15,573 million m3) and grey water (30,620 million m3) are outsourced. A "Virtual Water Strategy" is one measure which could alleviate water stress at the regional scale, with consideration of financial compensation from water receiving regions made to water supplying regions for achieving water management targets. We also found that physical water transfer to Jing-Jin-Ji could not balance virtual blue water exports. Our research suggests that a continuation of an export-based economic development model will worsen Hebei's water stress. Reducing the dependency of Hebei's sectoral economy on export of water intensive and low value added agricultural products may be one strategy to reduce the pressure on regional water

Association between Social Integration and Health among Internal Migrants in ZhongShan, China.

Directory of Open Access Journals (Sweden)

Yanwei Lin

Full Text Available Internal migrants are the individuals who migrate between regions in one country. The number of internal migrants were estimated at 245 million in China in 2013. Results were inconsistent in the literature about the relationship between their health statuses and social integration. The main difference exists on how to measure the social integration and whether health statuses of internal migrants improve with years of residence. To complement the existing literature, this study measured social integration more comprehensively and estimated the internal migrants' health statuses with varying years of residence, and explored the associations between the migrants' social integration and health. We used the data from 2014 Internal Migrant Dynamic Monitoring Survey of Health and Family Planning in ZhongShan, China. Health status was measured from four aspects: self-reported health, subjective well-being, perception of stress, mental health. We measured social integration through four dimensions: economy, social communication, acculturation, and self-identity. The analyses used multiple linear regressions to examine the associations between self-reported health, subjective well-being, and perception of stress, mental health and social integration. The analytical sample included 1,999 households of the internal migrants and 1,997 local registered households, who were permanent residents in ZhongShan. Among the internal migrants, Adults in the labor force, who were aged 25 to 44 years old, accounted for 91.2% of the internal migrant population, while 74.6% of the registered population were in that age group. Median residential time among migrants was 2.8 (1.3-6.2 years, and 20.2% of them were migrating in the same Guangdong province. Except for mental health, other health statuses among migrants had significant differences compared with local registered population, e.g. self-reported health was better, but subjective well-being was worse. However, these

Farmers of Jin county want fewer children.

Science.gov (United States)

Xiao, M

1986-04-01

The economic reform practiced in the vast rural areas in China gives a great impetus to the vigorous development of rural economy and the the rapid improvement of living standard. Meanwhile, reform pounds at the traditional childbearing ideas. The striking change in the childbearing attitudes of the farmers of the Jin County is a good example. As the farmers of the country are getting well-off when the commodity economy develops rapidly with the rural economic reforms, their childbearing attitudes change. Profound changes have taken place in their mode of production and their life style. The young couples of the county begin to seek small families instead of traditional big ones. They are convinced that under the new situation of reforms, the farmers of an old generation are in no way competent as the head of the family to guide production and therefore want to build their own small families by freeing themselves from the binds of the traditional patriarchal system. The increase in the cost of bringing up children and the economic loss resulting from the absence from work for looking after children constitute another reason to prefer a small family. The son is no more the only economic guarantee for the aged. As a result of the rapid development of the rural economy, a retirement system has been established among the farmers of the Jin county. "It is unreliable to expect that the son will support his aged parents. Now it is better to earn more money and the collective can be depended upon by the aged."

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

International Nuclear Information System (INIS)

Jang, Jong Sik; Kim, Sung Ho

2008-01-01

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

Energy Technology Data Exchange (ETDEWEB)

Jang, Jong Sik [Kyungpook National University, Daegu (Korea, Republic of); Kim, Sung Ho [Chonnam National University, Gwangju (Korea, Republic of)

2008-09-15

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients.

The Measurement of Urbanization Level Based on Entity Space: A Case Study of JingJinJi Region, China

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Wen Fenghua

2017-01-01

Full Text Available On the basis of analyzing the pros and cons of different urbanization level measurement methods, this paper puts forward urbanization level measurement method based on entity space and then uses entity space data to describe the urbanization rate of various districts and counties of JingJinJi Region in 2005 and 2009. According to the analysis of time and space differences on such basis, JingJinJi may be divided from high to low order according to the urbanization rate of the entity space: central urban area, urban development area and suburb, which respectively bear different functions. According to the comparison of entity space urbanization rate and population urbanization rate in the aspects of sequence, primacy ratio, zipf index, etc., we find the non-intensive land use status quo of urban development area of JingJinJi and the feature that the distribution of entity space urbanization scale is much uniform than distribution of population urbanization scale. Accordingly, the paper puts forward the following suggestions : (1 The space construction should depend upon function division; (2 The urban development area should pay attention to the construction of the supporting facilities and meanwhile enhance land use rate; (3 The urban construction should be enhanced in small and middle regions and counties surrounding Beijing and Tianjin.

AMS radiocarbon dating of cemetery of Jin Marquises in China

CERN Document Server

Wu, X; Wang, J; Guo, Z; Liu, K; Lü, X; Ma, H; Li, K; Yuan, J; Cai, L

2000-01-01

Bones are very important samples to determine the hosts of the cemetery of Jin Marquises which were excavated at Tianma-Qucun site in Shanxi Province in China. In order to obtain accurate AMS radiocarbon dates, bones were pretreated by two kinds of methods, the gelatin-extraction method and the amino-acid method. Charcoals collected from the same sites were also used. The measured dates agree with historical record.

Transcriptional control of the isoeugenol monooxygenase of Pseudomonas nitroreducens Jin1 in Escherichia coli.

Science.gov (United States)

Ryu, Ji-Young; Seo, Jiyoung; Ahn, Joong-Hoon; Sadowsky, Michael J; Hur, Hor-Gil

2012-01-01

Vanillin is one of the most valuable compounds in the flavoring and fragrance industries, and many attempts to produce natural vanillin have been made in recent years. Isoeugenol monooxygenase (Iem) converts the phenylpropanoid compound isoeugenol to vanillin. In Pseudomonas nitroreducens Jin1, the positive regulatory protein IemR is divergently expressed from Iem, and the promoter region is located between the genes. In this study, we investigated the transcriptional regulation of iem in Escherichia coli. We focused on inducers and regulatory protein IemR. Transcription of iem was found to be dependent on the amounts of isoeugenol and IemR. Isoeugenol was found to be the best inducer of iem, followed by trans-anethole, which induced iem to 58% of the transcription level observed for isoeugenol. Overproduction of IemR in E. coli significantly increased the transcription of iem, up to 96-fold, even in the absence of isoeugenol, as compared to basally expressed IemR. Results of this study indicate that the transcription of iem iss dependent on the type of inducers and on IemR. They should contribute to the development of bioengineering strategies for increased production of vanillin through high-level expression of the isoeugenol monooxygenase gene in microorganisms.

Experimental study of desulfurization of Zhong Liang Shau high sulfur coal by flotation

Energy Technology Data Exchange (ETDEWEB)

Jiang, Z.; Huang, B.; Cao, J. [China University of Mining and Technology (China). Beijing Graduate School

1994-12-01

Emission of large amount of SO{sub 2} from combustion of high sulfur coal causes serious environmental pollution. Pre-combustion desulfurization of high sulfur coal has become a necessity. This paper reports test results of fine coal desulfurization with different flotation technology and the effect of pyrite depressant. Test work showed that when the coal sample from Zhong Liang Shau was processed with a Free Jet Flotation Column its pyritic sulfur content was reduced from 3.08% to 0.84%, with 72.22% recovery of combustible matter in clean coal. The concept of Desulfurization Efficiency Index E{sub ds} for comprehensive evaluation of desulfurization process is proposed, which is defined as the product of the ratio of sulfur content reduction of clean coal and the recovery of combustible matters. 6 refs., 4 figs., 3 tabs.

[Evaluation on efficacy of Jin's "Sanzhen" therapy combined with rehabilitation training for hemiplegia of stroke patients by Fugl-Meyer scale].

Science.gov (United States)

Han, De-Xiong; Zhuang, Li-Xing; Zhang, Ying

2011-06-01

To assess the therapeutic effect of Jin's "Sanzhen" therapy combined with rehabilitation training on limb-motor function of stroke patients by using Fugl-Meyer scale. A total of 254 hemiplegic stroke outpatients and inpatients from 7 hospitals were randomly divided into Jin's "Sanzhen" (JSZ) group (n = 83), rehabilitation group (n = 84) and combination group (n = 87). Acupuncture was applied to acupoints of Jin's "Sanzhen" including Quchi (LI 11), Waiguan (SJ 5) and Hegu (LI 4); Futu (ST 32). Zusanli (ST 36) and Sanyinjiao (SP 6); etc. The acupuncture needles were retained for 30 min after "Deqi". Rehabilitation training included passive joint movement, standing-sitting training, tapping-pressing stimulation, walking training, etc. The treatment was conducted once daily, 5 sessions a week and for 4 weeks. Fugl-Meyer scale composed of 100-point motor domain of the upper- and lower-extremity sections was used to assess the patients' motor function. On day 28 after the treatment, of the 83.84 and 87 hemiplegic stroke patients in the JSZ, rehabilitation and combination groups, 48 (57.8%), 31 (36.9%) and 50 (57.5%) experienced marked improvement in their clinical symptoms and signs, 26 (31.3%), 44 (52.4%) and 31(35.6%) had an improvement, and 9 (10.8%), 9 (10.7%) and 6 (6.9%) failed in the treatment, with the total effective rates being 89.2%, 89.3% and 93.1%, respectively. The neurological deficit score (NDS) of the combination group was significantly lower than that of the rehabilitation group (P rehabilitation groups (P rehabilitation groups in both NDS and FMAS (P > 0.05). Jin's "Sanzhen" therapy combined with rehabilitation training can significantly improve the limb motor function of hemiplegic stroke patients, and has a good synergistic effect.

Lapset median käyttäjinä

OpenAIRE

Jalonen, Taru; Suomela, Sonja

2010-01-01

Laurea-ammattikorkeakoulu Tiivistelmä Hyvinkää Sosiaali-, terveys- ja liikunta-ala Hoitotyön koulutusohjelma Terveydenhoitaja AMK Sairaanhoitaja AMK Taru Jalonen, Sonja Suomela Lapset median käyttäjinä Vuosi ‎2010‎ Sivumäärä ‎63‎ Tämän opinnäytetyön tarkoituksena oli selvittää lasten tottumuksia ja kokemuksia mediasta sekä ‎niiden herättämiä tunteita. Lisäksi selvitimme lasten käyttämiä mediaympäristöjä sekä median ‎näkymistä lasten leikeissä. Tämä työ on os...

Study on embodied CO2 transfer between the Jing-Jin-Ji region and other regions in China: a quantification using an interregional input-output model.

Science.gov (United States)

Chen, Mengmeng; Wu, Sanmang; Lei, Yalin; Li, Shantong

2018-03-08

Jing-Jin-Ji region (i.e., Beijing, Tianjin, and Hebei) is China's key development region, but it is also the leading and most serious air pollution region in China. High fossil fuel consumption is the major source of both carbon dioxide (CO 2 ) emissions and air pollutants. Therefore, it is important to reveal the source of CO 2 emissions to control the air pollution in the Jing-Jin-Ji region. In this study, an interregional input-output model was applied to quantitatively estimate the embodied CO 2 transfer between Jing-Jin-Ji region and other region in China using China's interregional input-output data in 2010. The results indicated that there was a significant difference in the production-based CO 2 emissions in China, and furthermore, the Jing-Jin-Ji region and its surrounding regions were the main regions of the production-based CO 2 emissions in China. Hebei Province exported a large amount of embodied CO 2 to meet the investment, consumption, and export demands of Beijing and Tianjin. The Jing-Jin-Ji regions exported a great deal of embodied CO 2 to the coastal provinces of southeast China and imported it from neighboring provinces.

Interprovincial transfer of embodied energy between the Jing-Jin-Ji area and other provinces in China: A quantification using interprovincial input-output model.

Science.gov (United States)

Chen, Weiming; Wu, Sanmang; Lei, Yalin; Li, Shantong

2017-04-15

Commodity trade between regions implies a large amount of energy transfer. As an important economic growth pole of China, the Jing-Jin-Ji area (Beijing-Tianjin-Hebei) is also one of the areas with the largest energy consumption in China. Moreover, the primary energy consumer goods in this area are fossil fuels, such as coal. This has led to serious air pollution in the area. Therefore, the reduction of energy consumption under the premise of maintaining sustained economic growth is an important task of the Jing-Jin-Ji area. In this study, an interprovincial input-output model was applied to quantitatively estimate the embodied energy transfer between Jing-Jin-Ji area and other provinces in China. The results indicated that the Metal and nonmetal mineral processing industry and the Electrical, gas and water industry in the Jing-Jin-Ji area exported a large amount of embodied energy to the Yangtze River Delta and the Pearl River Delta. However, the embodied energy export of the Jing-Jin-Ji area mainly exported by Hebei province. Beijing and Tianjin even have some net import of embodied energy. The embodied energy transfer between Tianjin, Hebei and other provinces was mainly driven by investment, while the main media of embodied energy transfer between Beijing and other provinces was consumption. Therefore, we suggest that the Jing-Jin-Ji area should further increase the degree of dependence on other provinces' energy-intensive products and reduce the export of energy-intensive products. In addition, there should be difference in the energy and industrial policies among Beijing, Tianjin and Hebei, and the problems of high energy consumption and high proportion of heavy industry in Hebei should be first resolved. Copyright © 2017 Elsevier B.V. All rights reserved.

Genoprotective effect of the Chinese herbal decoction xiao jian zhong tang.

Science.gov (United States)

Szeto, Yim-Tong; Cheng, Ngok-Fung; Pak, Sok-Cheon; Kalle, Wouter

2013-03-01

The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P < 0.05) was found for individual herb extracts, but XJZT showed protection of human lymphocytic DNA upon oxidative stress (P < 0.05). The in vitro DNA protection effect of XJZT was conferred by the synergistic effect of the herbs, while the individual herbs had no such effect.

Research of Ancient Architectures in Jin-Fen Area Based on GIS&BIM Technology

Science.gov (United States)

Jia, Jing; Zheng, Qiuhong; Gao, Huiying; Sun, Hai

2017-05-01

The number of well-preserved ancient buildings located in Shanxi Province, enjoying the absolute maximum proportion of ancient architectures in China, is about 18418, among which, 9053 buildings have the structural style of wood frame. The value of the application of BIM (Building Information Modeling) and GIS (Geographic Information System) is gradually probed and testified in the corresponding fields of ancient architecture’s spatial distribution information management, routine maintenance and special conservation & restoration, the evaluation and simulation of related disasters, such as earthquake. The research objects are ancient architectures in JIN-FEN area, which were first investigated by Sicheng LIANG and recorded in his work of “Chinese ancient architectures survey report”. The research objects, i.e. the ancient architectures in Jin-Fen area include those in Sicheng LIANG’s investigation, and further adjustments were made through authors’ on-site investigation and literature searching & collection. During this research process, the spatial distributing Geodatabase of research objects is established utilizing GIS. The BIM components library for ancient buildings is formed combining on-site investigation data and precedent classic works, such as “Yingzao Fashi”, a treatise on architectural methods in Song Dynasty, “Yongle Encyclopedia” and “Gongcheng Zuofa Zeli”, case collections of engineering practice, by the Ministry of Construction of Qing Dynasty. A building of Guangsheng temple in Hongtong county is selected as an example to elaborate the BIM model construction process based on the BIM components library for ancient buildings. Based on the foregoing work results of spatial distribution data, attribute data of features, 3D graphic information and parametric building information model, the information management system for ancient architectures in Jin-Fen Area, utilizing GIS&BIM technology, could be constructed to support the

Research of Ancient Architectures in Jin-Fen Area Based on GIS and BIM Technology

International Nuclear Information System (INIS)

Jia, Jing; Zheng, Qiuhong; Gao, Huiying; Sun, Hai

2017-01-01

The number of well-preserved ancient buildings located in Shanxi Province, enjoying the absolute maximum proportion of ancient architectures in China, is about 18418, among which, 9053 buildings have the structural style of wood frame. The value of the application of BIM (Building Information Modeling) and GIS (Geographic Information System) is gradually probed and testified in the corresponding fields of ancient architecture’s spatial distribution information management, routine maintenance and special conservation and restoration, the evaluation and simulation of related disasters, such as earthquake. The research objects are ancient architectures in JIN-FEN area, which were first investigated by Sicheng LIANG and recorded in his work of “Chinese ancient architectures survey report”. The research objects, i.e. the ancient architectures in Jin-Fen area include those in Sicheng LIANG’s investigation, and further adjustments were made through authors’ on-site investigation and literature searching and collection. During this research process, the spatial distributing Geodatabase of research objects is established utilizing GIS. The BIM components library for ancient buildings is formed combining on-site investigation data and precedent classic works, such as “Yingzao Fashi”, a treatise on architectural methods in Song Dynasty, “Yongle Encyclopedia” and “Gongcheng Zuofa Zeli”, case collections of engineering practice, by the Ministry of Construction of Qing Dynasty. A building of Guangsheng temple in Hongtong county is selected as an example to elaborate the BIM model construction process based on the BIM components library for ancient buildings. Based on the foregoing work results of spatial distribution data, attribute data of features, 3D graphic information and parametric building information model, the information management system for ancient architectures in Jin-Fen Area, utilizing GIS and BIM technology, could be constructed to support

Even a monkey can understand fan activism: Political speech, artistic expression, and a public for the Japanese dôjin community

Directory of Open Access Journals (Sweden)

Alex Leavitt

2012-06-01

Full Text Available We examine the creation of dôjinshi works critiquing the passage of the metropolitan Tokyo ordinance Bill 156 in December 2010 as a case of fan-driven political activism. Bill 156 aims to limit artistic freedom and is specifically targeted at anime, manga, and other works of visual pop culture. Fans who participate in dôjin production perform both a love for this media and an active form of citizenship that is historically fannish but transformative beyond the mere appropriation and remix of media texts. We argue that dôjin fans and works constitute a recursive public, wherein participants actively create discourse around artistic and ideological issues while engaging in added layers of discourse regarding the maintenance of their existence as a public. We examine fan discourse and dôjin works engaging Bill 156 as an object for political activism, as anime and manga otaku perform their citizenship in the wider society of Japan for their local public and for a global audience of like-minded fans.

[Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen : Stadt, Land und Konfession 1500-1721. Teil 4. Hrsg. von Matthias Asche, Werner Buchholtz und Anton Schindlin

Index Scriptorium Estoniae

Maasing, Madis, 1984-

2013-01-01

Arvustus: Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen : Stadt, Land und Konfession 1500-1721. Teil 4. (Katholisches Leben und Kirchenreform im Zeitalter der Glaubensspaltung, 72). Hrsg. von Matthias Asche, Werner Buchholtz und Anton Schindling. Verlag Aschendorff. Münster 2012

The Impact of Land Use and Land Cover Change on Water Yield in the Jing- Jin-Ji Region in China

Science.gov (United States)

Li, Suxiao; Yang, Hong

2017-04-01

Water yield is one of the key ecosystem services sustaining both people's life and economic development. However, the water yield function is sensitive to anthropogenic activity especially the land use and land cover change (LUCC). Assessment of historical LUCC and its impact on water yield could benefit designing and implementing appropriate land use strategy that enhance the water yield capacity. Beijing (Jing) and its surrounding areas of Tianjin (Jin) and Hebei (Ji) is the political, cultural and economic center of China. The region is facing increasingly water crisis. Taking the Jing-Jin-Ji region as a study area, this study analyzed the historical LUCC and its impact on water yield by using the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) model to spatially map and quantify the changes of water yield from 1995 to 2010. The results showed there was main decline in area of wetland and forest and increase in area of crop land and built up land. An abrupt decline in water yield was found for year 2000. The water yield was influenced to a great extent by precipitation and evapotranspiration, but the land use played an important role in the water yield capacity (water yield per unit area) through plant cover that affected evapotranspiration, soil water permeability and the capacity of holding the moisture content. By general ranking, the water yield capacity of different land use type was as follows: built-up>bare land>cropland> grassland>forest >wetland, which illustrated that the built-up and bare land had higher run off rate while the vegetation area had higher capacity to control surface run off to increase the groundwater. A good understanding of temporal-spatial allocation of historical LUCC and Water yield of the Jing-Jin-Ji region could help guide land use policy decisions that take into consideration of tradeoffs with respect to spatial distribution of ecosystem services amongst the three administrative entities (Jing-Jin-Ji) and

Meeting the challenge of future energy supply from the perspective of Royal Dutch Shell. An interview with Matthias Bichsel

Energy Technology Data Exchange (ETDEWEB)

Bollinger, D. (ed.); Gunzenhauser, B. [Vice-President of the Association of Swiss Petroleum Geologists and Engineers, c/o Interoil AG, Zuerich (Switzerland)

2009-07-01

In this comprehensive interview in the Swiss Bulletin for Practical Geology with Matthias Bichsel, Director of Projects and Technology at Royal Dutch Shell plc, the subject of 'Peak Oil' is discussed. The question is asked on how Shell deals with the fact that oil and gas resources are limited and sooner or later will be more or less depleted or can only be used at high cost. A further topic discussed deals with how Shell wants to satisfy current shareholder interests. At the same time the company needs to be led into a viable and successful future. Shell's efforts to position itself in this difficult situation are discussed. The development of resource estimates, environmental responsibility and sustainability are further topics examined. Current scenarios are looked at and how Shell aims to solve the dilemma of meeting doubling energy demand is discussed. Finally, new technologies and renewable alternatives are looked at

XU Jian-zhong (许建中)——An Outstanding Doctor of Integrative Medicine on Respiratory Diseases

Institute of Scientific and Technical Information of China (English)

无

2001-01-01

@@Professor XU Jian-zhong was born in a family of traditional Chinese doctor in Beijing, August, 1930. His native place is Putian, Fujian Province. Prof. XU has engaged for more than 40 years in clinical medicine since he was graduated from Shanxi Medical University in 1954. From 1958 to 1961, he was released from work to attend the TCM Learning Class for Doctors of Western Medicine for 3 years and granted the first grade prize by the Ministry of Health at graduation. Since then, the integration of traditional Chinese and western medicine (TCM-WM) has been the cause he devoted himself to. Now, he is Chief Doctor in Xiyuan Hospital, China Academy of Traditional Chinese Medicine, visiting professor of postgraduate education Department of China Academy of TCM, and Director of Specialty Committee of Respiratory Diseases, Chinese Association of Integration of Traditional and Western Medicine (CAIM).

The impact of the "Air Pollution Prevention and Control Action Plan" on PM2.5 concentrations in Jing-Jin-Ji region during 2012-2020.

Science.gov (United States)

Cai, Siyi; Wang, Yangjun; Zhao, Bin; Wang, Shuxiao; Chang, Xing; Hao, Jiming

2017-02-15

In order to cope with heavy haze pollution in China, the Air Pollution Prevention and Control Action Plan including phased goals of the fine particulate matter (PM 2.5 ) was issued in 2013. In this study, China's emission inventories in the baseline 2012 and the future scenarios of 2017 and 2020 have been developed based on this Action Plan. Beijing-Tianjin-Hebei (Jing-Jin-Ji) region, one of the most polluted regions in China, was taken as a case to assess the impact of phased emission control measures on PM 2.5 concentration reduction using WRF-CMAQ model system. With the implementation of the Action Plan, the emissions of sulfur dioxide (SO 2 ), nitrogen oxides (NO X ) , PM 2.5 , non-methane volatile organic compound (NMVOC), and ammonia (NH 3 ) in 2017 will decrease by36%, 31%, 30%,12%, and -10% from the 2012 levels in Jing-Jin-Ji, respectively. In 2020, the emissions of SO 2 , NO X, PM 2.5 , NMVOC, and NH 3 will decrease by 40%, 44%, 40%, 22%, and -3% from the 2012 levels in Jing-Jin-Ji, respectively. Consequently, the ambient annual PM 2.5 concentration under the scenarios of 2017 and 2020 will be 28.3% and 37.8% lower than those in 2012, respectively. The Action Plan provided an effective approach to alleviate PM 2.5 pollution level in Jing-Jin-Ji region. However, emission control of NMVOC and NH 3 should be paid more attention and be strengthened in future. Meanwhile, emission control of NO x , SO 2 , NH 3 and NMVOC synergistically are highly needed in the future because multiple pollutants impact on PM 2.5 and O 3 concentrations nonlinearly. Copyright © 2016 Elsevier B.V. All rights reserved.

Effectiveness of Traditional Chinese Medicine Compound JieDuTongLuoShengJin Granules Treatment in Primary Sjögren’s Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Directory of Open Access Journals (Sweden)

Ben Li

2017-01-01

Full Text Available Objective. To evaluate the clinical therapeutic efficacy and safety of JieDuTongLuoShengJin granules + HCQ in patients with pSS. Methods. 40 patients with low-activity-level pSS and without visceral involvement participated in this study and were randomized to receive either JieDuTongLuoShengJin granules with HCQ or placebo with HCQ. Patients and investigators were blinded to treatment allocation. The primary endpoint was week 12 ESSPRI score, while secondary endpoints included ESSDAI, salivary and lacrimal gland function, and some laboratory variables. Safety-related data were also assessed. Results. Comparing with the placebo group, the treatment group experienced statistically significant improvement in the mean change from baseline for the primary endpoint of ESSPRI score and also in PGA. Moreover, in comparison with baseline values, the treatment group had significantly improved ESSDAI score, unstimulated saliva flow rate, and several laboratory variables. However, upon comparison of the two groups, there were no significant differences for them. The incidence of AEs was 10.0%, one in treatment group and three in placebo group. Conclusion. Treatment with a combination of JieDuTongLuoShengJin granules with HCQ is effective in improving patients’ subjective symptoms and some objective indicators of pSS. These results indicate that JieDuTongLuoShengJin is promising as a safe and effective treatment of pSS.

Discussion of FAN Zhong-yan’s Buddhist Thought and Personality Spirit%论范仲淹的佛禅思想及其人格精神

Institute of Scientific and Technical Information of China (English)

邢爽; 胡遂

2014-01-01

FAN Zhong-yan’s life ambition is to make the monarch as wise as Yao and Shun.He begged the ancient heart of Habitat for Humanity in his “YueYang Tower Notes”,“not pleased,not to have com-passion,”the implication was obvious Buddhist ideas with.The fusion of Confucianism and Buddhism thought of Fan Zhong-yan for the later generations to establish the “independent personality model un-moved either by gain or loss”.His life is spent in the pursuit and practice of Mahayana Bodhisattva “the highest state of compassion for the world of vision”,“being and not being”in perfect unity.%范仲淹的一生志在致君尧舜。《岳阳楼记》中他“尝求古仁人之心”，“不以物喜，不以己悲”的思想俨然带有佛家的意味。融合儒释思想的范仲淹为后来的士人树立了“宠辱不惊”的独立人格典范。他的一生都在追求和践行大乘菩萨道“悲心宏愿”的最高境界，为世人诠释了“有无之境”的完美统一。

Consumption-based Total Suspended Particulate Matter Emissions in Jing-Jin-Ji Area of China

Science.gov (United States)

Yang, S.; Chen, S.; Chen, B.

2014-12-01

The highly-industrialized regions in China have been facing a serious problem of haze mainly consisted of total suspended particulate matter (TSPM), which has attracted great attention from the public since it directly impairs human health and clinically increases the risks of various respiratory and pulmonary diseases. In this paper, we set up a multi-regional input-output (MRIO) model to analyze the transferring routes of TSPM emissions between regions through trades. TSPM emission from particulate source regions and sectors are identified by analyzing the embodied TSPM flows through monetary flow and carbon footprint. The track of TSPM from origin to end via consumption activities are also revealed by tracing the product supply chain associated with the TSPM emissions. Beijing-Tianjin-Hebei (Jing-Jin-Ji) as the most industrialized area of China is selected for a case study. The result shows that over 70% of TSPM emissions associated with goods consumed in Beijing and Tianjin occurred outside of their own administrative boundaries, implying that Beijing and Tianjin are net embodied TSPM importers. Meanwhile, 63% of the total TSPM emissions in Hebei Province are resulted from the outside demand, indicating Hebei is a net exporter. In addition, nearly half of TSPM emissions are the by-products related to electricity and heating supply and non-metal mineral products in Jing-Jin-Ji Area. Based on the model results, we provided new insights into establishing systemic strategies and identifying mitigation priorities to stem TSPM emissions in China. Keywords: total suspended particulate matter (TSPM); urban ecosystem modeling; multi-regional input-output (MRIO); China

Iklan Sebagai Media Kritik Sosial (Pesan Simbolik Iklan Kretek Djarum 76 Seri Jin

Directory of Open Access Journals (Sweden)

Firdaus Azwar Ersyad

2016-04-01

Full Text Available The presence of television advertising is a prayer one way to manufacturer for review introduce and selling products for society. Regarding the regulation of advertising especially cigarettes and tobacco products manufacturer in order to encourage creative hearts introducing more on audience their product . As a result , the creativity in the hearts smoking ads aimed lifting product image so not operate direct products display .Singer study originated from the interest against visualization advertisements Djarum 76 series java jin  has its own peculiarities compared to other products . Zoom the one consolation is not revealed that an advertiser is selling products . Views are interpreted by different groups various ad viewers, but the views can be grouped into some basic ideas

BANGUNAN TINGGI MULTI FUNGSI SEBAGAI SINTESIS ARSITEKTUR DAN STRUKTUR Studi Analisis Jin Mao Tower Grand Hyatt Shanghai

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Jimmy Priatman

2005-01-01

Full Text Available More than two decades, after the emerging of post- modern architecture, the split between construction technology and cultural expression in architecture appeared to become wider and wider. With the exception of a few "high-tech" buildings, the unity of art and applied science (technology in design seems facing challenges. It is interesting to see how fast and unexpectedly the situation has changed. Many factors and people played a role in this reversal, many new buildings demonstrate that utilitarian artifacts do not have to be oppressive to creativity but can evoke new innovation. One of the most significant contributors was JIN MAO TOWER at Shanghai, China. The paper analyses this building as a genuine synthesis of rational intelligence with art poetry that is still possible. Abstract in Bahasa Indonesia : Lebih dari dua dekade setelah timbulnya arsitektur pasca modern, pemisahan antara tekknologi konstruksi dan ekspresi kultural dalam arsitektur menjadi semakin lebar. Dengan perkecualian beberapa gedung "high-tech", kesatuan antara seni dan teknologi dalam tahap desain terlihat menghadapi tantangan tantangan. Tetapi menarik untuk diamati bahwa situasi telah berubah. Banyak faktor dan tokoh tokoh arsitek memegang peranan penting dalam perubahan ini, banyak bangunan bangunan baru mendemontrasikan bahwa artefak fungsionil tidak bearti menindas kreativitas namun dapat membangkitkan inovasi baru. Salah satu kontributor yang sangat penting adalah JIN MAO TOWER di Shanghai-China. Makalah ini membahas bangunan tersebut sebagai sintesis orijinal yang masih memungkinkan antara kecerdasan rasional dengan puisi seni arsitektur. Kata kunci: Sintesis.

SDE and SPME Analysis of Flavor Compounds in Jin Xuan Oolong Tea.

Science.gov (United States)

Sheibani, Ershad; Duncan, Susan E; Kuhn, David D; Dietrich, Andrea M; O'Keefe, Sean F

2016-02-01

Simultaneous distillation-extraction (SDE) and solid phase micro extraction (SPME) are procedures used for the isolation of flavor compounds in foods. The purpose of this study was to optimize SDE conditions (solvent and time) and to compare SDE with SPME for the isolation of flavor compounds in Jin Xuan oolong tea using GC-MS and GC-O. The concentration of volatile compounds isolated with diethyl ether was higher (P < 0.05) than for dichloromethane and concentration was higher at 40 min (P < 0.05) than 20 or 60 min extractions. For SDE, 128 volatiles were identified using GC-MS and 45 aroma active compounds using GC-O. Trans-nerolidol was the most abundant compound in oolong tea. The number of volatiles identified using GC-MS was lower in SPME than SDE. For SPME, 59 volatiles and 41 aroma active compounds were identified. The composition of the volatiles isolated by the 2 methods differed considerably but provided complementary information. © 2016 Institute of Food Technologists®

Main agronomic traits and resistance to rice blast of space-induced mutant lines of Zhong-er-ruan-zhan

International Nuclear Information System (INIS)

Xiao Wuming; Wang Hui; Liu Yongzhu; Guo Tao; Chen Zhiqiang; Yang Qiyun; Zhu Xiaoyuan

2012-01-01

The main agronomic traits and resistance to rice blast of 34 space-induced lines from an elite rice cultivar, Zhong-er-ruan-zhan were evaluated at their SP 4 . The resistance to blast of the mutant lines had been tested by two blast isolates previously. It was found that the mutant lines showed significant difference in plant height, effective panicles, panicle length and grains per panicle etc. from their parent. The range of variation in 1000-grain weight the largest, followed by the seed-setting rate, and that of effective panicles was the least among all the traits. Except for the line Z34, 33 mutant lines had broader resistance spectra than the wild-type based on the test with 38 different blast isolates, and all the 33 lines were also resistant to the panicle blast in the field. The result confirmed that selection for resistant to blast in lower generations was reliable. Taking account of agronomic traits and blast resistance, promising lines with resistance to blast and good agronomic characters could be selected from those mutant lines. Therefore, the elite rice germplasm with enhanced disease resistance can be produced. (authors)

Diglossie et biculturalisme littéraires :le cas de A Free Life, de Ha Jin

OpenAIRE

Perrin, Isabelle

2013-01-01

Le roman La Liberté de vivre, de Ha Jin, place son lecteur face à un type d’« écriture-traduction », puisqu’il suit le parcours d’un Chinois contraint par son exil aux États-Unis après les événements de Tian’anmen d’adopter la langue et la culture américaines. La représentation mimétique du réel joue sur le concept d’étrangeté, que le texte fait fonctionner en miroir : étrangeté des référents langagiers et culturels américains pour le héros chinois, étrangeté des référents langagiers et cultu...

Space-time PM2.5 mapping in the severe haze region of Jing-Jin-Ji (China) using a synthetic approach.

Science.gov (United States)

He, Junyu; Christakos, George

2018-05-07

Long- and short-term exposure to PM 2.5 is of great concern in China due to its adverse population health effects. Characteristic of the severity of the situation in China is that in the Jing-Jin-Ji region considered in this work a total of 2725 excess deaths have been attributed to short-term PM 2.5 exposure during the period January 10-31, 2013. Technically, the processing of large space-time PM 2.5 datasets and the mapping of the space-time distribution of PM 2.5 concentrations often constitute high-cost projects. To address this situation, we propose a synthetic modeling framework based on the integration of (a) the Bayesian maximum entropy method that assimilates auxiliary information from land-use regression and artificial neural network (ANN) model outputs based on PM 2.5 monitoring, satellite remote sensing data, land use and geographical records, with (b) a space-time projection technique that transforms the PM 2.5 concentration values from the original spatiotemporal domain onto a spatial domain that moves along the direction of the PM 2.5 velocity spread. An interesting methodological feature of the synthetic approach is that its components (methods or models) are complementary, i.e., one component can compensate for the occasional limitations of another component. Insight is gained in terms of a PM 2.5 case study covering the severe haze Jing-Jin-Ji region during October 1-31, 2015. The proposed synthetic approach explicitly accounted for physical space-time dependencies of the PM 2.5 distribution. Moreover, the assimilation of auxiliary information and the dimensionality reduction achieved by the synthetic approach produced rather impressive results: It generated PM 2.5 concentration maps with low estimation uncertainty (even at counties and villages far away from the monitoring stations, whereas during the haze periods the uncertainty reduction was over 50% compared to standard PM 2.5 mapping techniques); and it also proved to be computationally very

China’s International Behavior. Activism, Opportunism, and Diversification

Science.gov (United States)

2009-01-01

assessments of their national goals, see Yan Xuetong, Guoji Zhengzhi yu Zhong - guo [International Politics and China], Beijing , China: Beijing Daxue ...Decisions: Important State Strategies After 1989], Beijing , China: Zhong - yang Dangli Chubanshe, 2004, pp. 783–806. 11 Swaine and Tellis, 2000, pp. 1–20...at the Conference on East Asian Security, Beijing , China, December 15, 2003; and Wang Yi, “Quanqiuhua Jincheng Zhong de Yazhou Quyu Hezuo” [Asian

Dynamic Changes Analysis and Hotspots Detection of Land Use in the Central Core Functional Area of Jing-Jin-Ji from 2000 to 2015 Based on Remote Sensing Data

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Yafei Li

2017-01-01

Full Text Available The article uses GIS spatial analysis and grid technologies to study the dynamic changes, hotspot regions, and driving forces in land use of the central core functional area of Jing-Jin-Ji. The research results are as follows: from 2000 to 2015, the main types of land use in the central core functional area of Jing-Jin-Ji are cultivated land, woodland, and built-up land. In the period of 2005–2010, the transfer between built-up land and cultivated land was frequent. The dynamic degree of single land use in unused land was highest. It also finds out that the dynamic degree of the integrated land use from 2005 to 2010 was higher. The center of gravity transfer of the dynamic degree of integrated land use was concentrated in research area. As for the hotspots, their number and scope are increasing, and the positions located in the edge of original main urban area and developed transportation network. The main characteristics of land use dynamic change in the study area are the rapid decrease of cultivated land area and rapid growth of built-up land. The spatial agglomeration of economic factors caused by human activities has an important influence on the spatial and temporal dynamic changes of land use.

Generation of CRISPR/Cas9-mediated bicistronic knock-in ins1-cre driver mice.

Science.gov (United States)

Hasegawa, Yoshikazu; Hoshino, Yoshikazu; Ibrahim, Abdelaziz E; Kato, Kanako; Daitoku, Yoko; Tanimoto, Yoko; Ikeda, Yoshihisa; Oishi, Hisashi; Takahashi, Satoru; Yoshiki, Atsushi; Yagami, Ken-Ichi; Iseki, Hiroyoshi; Mizuno, Seiya; Sugiyama, Fumihiro

2016-07-29

In the present study, we generated novel cre driver mice for gene manipulation in pancreatic β cells. Using the CRISPR/Cas9 system, stop codon sequences of Ins1 were targeted for insertion of cre, including 2A sequences. A founder of C57BL/6J-Ins1(em1 (cre) Utr) strain was produced from an oocyte injected with pX330 containing the sequences encoding gRNA and Cas9 and a DNA donor plasmid carrying 2A-cre. (R26GRR x C57BL/6J-Ins1(em1 (cre) Utr)) F1 mice were histologically characterized for cre-loxP recombination in the embryonic and adult stages; cre-loxP recombination was observed in all pancreatic islets examined in which almost all insulin-positive cells showed tdsRed fluorescence, suggesting β cell-specific recombination. Furthermore, there were no significant differences in results of glucose tolerance test among genotypes (homo/hetero/wild). Taken together, these observations indicated that C57BL/6J-Ins1(em1 (cre) Utr) is useful for studies of glucose metabolism and the strategy of bicistronic cre knock-in using the CRISPR/Cas9 system could be useful for production of cre driver mice.

A facile stereospecific synthesis of (Z)-2-sulfonyl-substituted 1,3-enynes via Sonogashira coupling of (E)-α-iodovinyl sulfones with 1-alkynes

Institute of Scientific and Technical Information of China (English)

无

2007-01-01

(E)-α-Iodovinyl sulfones 1 underwent the Sonogashira coupling reactions with terminal alkynes 2 in piperidine at room temperature in the presence of 5 mol% of Pd(PPh3)4 and 10 mol% of CuI to stereospecifically afford the corresponding (Z)-2-sulfonyl-substituted 1,3-enynes 3 in high yields.(C) 2007 Ming Zhong Cai. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

Gu Jin Tan Gai with the Perspective of Carnival Poetics%狂欢诗学视域下的《古今谭概》

Institute of Scientific and Technical Information of China (English)

刘云春; 赵豫科

2014-01-01

《古今谭概》是晚明著名文学家冯梦龙编纂的一部笑话集。他在博览历代正史、稗官野史的基础上，选取众多可笑有趣的逸闻趣事，以戏谑的口吻略加评点，遂成此集。《古今谭概》内容多为真人真事，上自历代君主，下至市井百姓，各色人等，种种笑话，应有尽有。本文运用文艺理论家巴赫金的狂欢诗学理论，从时空狂欢、语言狂欢、体裁狂欢、狂欢的内核几个层面对其进行解读，论述了作品产生的时代背景和狂欢化艺术特色，旨在发掘文本内涵，拓宽文本研究视野，发现其更深层次的文学价值。%Gu Jin Tan Gai is a collection of jokes compiled by Feng Menglong. He selects many stories from the official history and the romance and comments in a bantering tone. A majority of the content is true which in-cludes emperors and common people. This paper uses the Russian literary theorist Bakhtin's Carnival Poetics theory to discuss four aspects:space - time carnival,language carnival,style carnival,carnival essence. The paper dis-cusses the background and carnival artistic characteristics of Gu Jin Tan Gai to find the deeper value of literature.

Molecular and Ultrastructural Mechanisms Underlying Yellow Dwarf Symptom Formation in Wheat after Infection of Barley Yellow Dwarf Virus.

Science.gov (United States)

Rong, Wei; Wang, Xindong; Wang, Xifeng; Massart, Sebastien; Zhang, Zengyan

2018-04-13

Wheat ( Tritium aestivum L.) production is essential for global food security. Infection of barley yellow dwarf virus-GAV (BYDV-GAV) results in wheat showing leaf yellowing and plant dwarfism symptom. To explore the molecular and ultrastructural mechanisms underlying yellow dwarf symptom formation in BYDV-GAV-infected wheat, we investigated the chloroplast ultrastructure via transmission electron microscopy (TEM), examined the contents of the virus, H₂O₂, and chlorophyll in Zhong8601, and studied the comparative transcriptome through microarray analyses in the susceptible wheat line Zhong8601 after virus infection. TEM images indicated that chloroplasts in BYDV-GAV-infected Zhong8601 leaf cells were fragmentized. Where thylakoids were not well developed, starch granules and plastoglobules were rare. Compared with mock-inoculated Zhong8601, chlorophyll content was markedly reduced, but the virus and H₂O₂ contents were significantly higher in BYDV-GAV-infected Zhong8601. The transcriptomic analyses revealed that chlorophyll biosynthesis and chloroplast related transcripts, encoding chlorophyll a/b binding protein, glucose-6-phosphate/phosphate translocator 2, and glutamyl-tRNA reductase 1, were down-regulated in BYDV-GAV-infected Zhong8601. Some phytohormone signaling-related transcripts, including abscisic acid (ABA) signaling factors (phospholipase D alpha 1 and calcineurin B-like protein 9) and nine ethylene response factors, were up-regulated. Additionally, reactive oxygen species (ROS)-related genes were transcriptionally regulated in BYDV-GAV infected Zhong8601, including three up-regulated transcripts encoding germin-like proteins (promoting ROS accumulation) and four down-regulated transcripts encoding peroxides (scavenging ROS). These results clearly suggest that the yellow dwarf symptom formation is mainly attributed to reduced chlorophyll content and fragmentized chloroplasts caused by down-regulation of the chlorophyll and chloroplast biosynthesis

Experimental study of the protective effects of Zhongfei decoction on radiation-induced pneumonia in rats

International Nuclear Information System (INIS)

Wang Yuezhen; Ma Shenglin; Zhang Aiqin; Feng Jianguo; Fang Xianhua; Sun Xiaojiang; Bao Yejiang

2007-01-01

Objective: To investigate the protective effect and its possible mechanism of ZhongFei Decoction on radiation-induced pneumonia in rats. Methods: Single irradiation was given at two thorax of female Wistar rats with 30 Gy of 6 MV X irradiation. Sixty rats were randomly divided into the control group, radiation group, radiation plus DXM and ZhongFei Decoction plus radiation group. On days 14 and 28 after treatment, 5 rats of each group were sacrificed, and their lungs were harvested for measurement of the lung index, the difference of the histopathology change, the concentration of hydroxyproline (hyp), and expression of transforming growth factor-β1 in lungs were analyzed by HE stain, biochemical method and immunohistochemical method, respectively. Results: The pathological study showed marked lung injury in the radiation group while only slight hyperemia hemorrhage, exudation and thickness of alveolar walls in the lungs of ZhongFei Decoction plus radiation group, the concentration of hydroxyproline and expression of TGF-β1 in the radiation lungs increased compared with that in the control group and reduced in the ZhongFei Decoction plus radiation group compared with that in the radiation group. Conclusions: ZhongFei Decoction could have protective effects on the radiation-induced pneumonia and the mechanism of its may be related with down-regulating the expression of TGF-β1 in the irritated lung tissue. (authors)

Study of provenance character on ancient celadon of Jin Dynasty produced in Yaozhou Kiln of Lidipo and Shangdian using nuclear technology

International Nuclear Information System (INIS)

Wang, Y.Q.; Feng, S.L.; Feng, X.Q.; Lei, Y.; Cheng, L.; Xu, Q.; Zhou, Z.X.; Xue, D.X.

2005-01-01

Yaozhou ware is a typical product of celadon porcelain in northern China. It was very famous for the various color glazes, multiple utensils and unique grain pattern. Yaozhou kiln series were made of Tongchuan, Lidipo, Shangdian, Chenlu kiln site and etc in Shanxi Province of china. It is one of seven kiln series in China. Celadon samples of 63 pieces of sherds were collected, which excavated in stratum of Jin Dynasty (1127-1234A.D.) from Yaozhou kiln of Lidipo and Shangdian sites. The main and trace elements of theses specimens were analyzed by NAA and EDXRF respectively. The contents of 10 main and 18 trace elements were determined precisely. The experimental data are performed with factor and discrimination analysis of statistic method. The result indicates that the trace elements can reveal the provenance character of porcelain better than main compositions.

Impacts of Land-Use and Land-Cover Changes on Water Yield: A Case Study in Jing-Jin-Ji, China

Directory of Open Access Journals (Sweden)

Suxiao Li

2018-03-01

Full Text Available Knowing the impact of land-use and land-cover (LULC changes on the distribution of water yield (WY is essential for water resource management. Using the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST model, we investigated the spatial-temporal variations of WY from 1990 to 2015 in China’s northern semi-arid region of Beijing–Tianjin–Hebei (Jing-Jin-Ji. We quantified the combined effects of LULC dynamics and climatic variation on WY. Furthermore, we identified the relative contribution of main LULC types to WY. For our study region, the built-up area increased by 35.66% (5380 km2 during the study period. In the meantime, cropland, grassland, and wetland decreased continuously. The expansion of built-up area and decline of vegetated land led to an increase of 1047 million m3 (5.1% in total WY. The impacts of LULC changes on WY were mainly determined by the biophysical characteristics of LULC composition. Vegetated land has relatively lower WY coefficients due to higher rates of evapotranspiration and water infiltration. Built-up areas and bare land have higher WY coefficients as a result of their impermeable surface. The spatial-temporal analysis of WY with specification of WY coefficients by LULC types can facilitate integrated land-use planning and water resource management.

JPRS Report, Soviet Union, Problems of the Far East, No. 1, January-February 1987

Science.gov (United States)

1987-07-22

Features of Socialism", Beijing zhengfa xuean xuebao, 1982, No. 1; Chen Zhong , On the Basic Features of Socialism, Xueshu yuekan, 1981, No. 1; etc. 18...34, Beijing daxue xuebao, 1985, No. 2, pp. 120-126; Yun Jing, "De- velopment of Collective and Individual Economies", Guangdong waishi, 1985, No. 1, pp. 8...Zhang Zhouyuan, et al, Shanghai, Renmin chubanshe, 1978-1979; On Distribution According to Work, A Collection of Articles, Beijing renmin chubanshe

Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.

Science.gov (United States)

Deng, Shan; Hu, Bing; An, Hong-Mei; Du, Qin; Xu, Ling; Shen, Ke-Ping; Shi, Xiu-Feng; Wei, Meng-Meng; Wu, Yang

2013-06-08

Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish effective herbal formula for colorectal cancer treatment. Based on TCM principles and clinical practices, we have established an eight herbs composed formula for colorectal cancer treatment, which is Teng-Long-Bu-Zhong-Tang (TLBZT). We have demonstrated the anticancer effects of TLBZT against colorectal carcinoma in vitro. In present study, we evaluated the anticancer potential of TLBZT, used alone or in combination with low dose of 5-Fluorouracil (5-Fu), in CT26 colon carcinoma in vivo. CT26 colon carcinoma was established in BALB/c mice and treated with TLBZT, 5-Fu, or TLBZT plus 5-Fu. The tumor volumes were observed. Apoptosis was detected by TUNEL assay. Caspases activities were detected by colorimetric assay. Cell senescence was indentified by senescence β-galactosidase staining. Gene expression and angiogenesis was observed by immunohistochemistry or western blot. TLBZT significantly inhibited CT26 colon carcinoma growth. TLBZT elicited apoptosis in CT26 colon carcinoma, accompanied by Caspase-3, 8, and 9 activation and PARP cleavage, and downregulation of XIAP and Survivin. TLBZT also induced cell senescence in CT26 colon carcinoma, with concomitant upregulation of p16 and p21 and downregulation of RB phosphorylation. In addition, angiogenesis and VEGF expression in CT26 colon carcinoma was significantly inhibited by TLBZT treatment. Furthermore, TLBZT significantly enhanced anticancer effects of 5-Fu in CT26 colon carcinoma. TLBZT exhibited significantly anticancer effect, and enhanced the effects of 5-Fu in CT26 colon carcinoma, which may correlate with induction of apoptosis and cell senescence, and angiogenesis inhibition. The present study provides new insight into TCM approaches for colon cancer treatment that are worth of further study.

The cost-effectiveness analysis of JinQi Jiangtang tablets for the treatment on prediabetes: a randomized, double-blind, placebo-controlled, multicenter design.

Science.gov (United States)

Sun, Xiao; Guo, Liping; Shang, Hongcai; Ren, Ming; Wang, Yue; Huo, Da; Lei, Xiang; Wang, Hui; Zhai, Jingbo

2015-11-03

reduced the incidence of diabetes mellitus and enhanced reversion rate. compared with the control group (p 0.05); finally the compliance of participants between the two groups had no significant difference. The cost-effectiveness analysis outcomes:in the intervention period of 12 months,on the aspect of reversion rate, the treatment group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio;on the aspect of the incidence of diabetes, the control group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio; in the follow-up period of 24 months, on the aspect of reversion rate, the treatment group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio, on the aspect of the incidence of diabetes, the control group had better economic advantage by using cost-effectivenes ratio and the incremental cost-effectiveness ratio.At the same time, these outcomes remained the same by sensitivity analysis. Assuming that prices and resident incomes rose 5%, the sensitiveness analysis shows that the two group affected by the paremeters changed little. The importance and effectiveness of lifestyle education and JinQi Jiangtang tablets was proven. In both the intervention period and follow-up, JinQi Jiangtang tablets combined with lifestyle education had a greater cost advantage effect than the lifestyle education alone on the reversion rate; the lifestyle education had a greater cost advantage effect than the JinQi Jiangtang tablets combined with lifestyle education on the incidence of diabetes. Chinese Clinical Trials ChiCTR-TRC-09000401 ) , registered on 25 May 2009.

金批«西厢»美学论%On Aesthetic Thought of Jin Shengtan’ s Comments on The Romance of West Chamber

Institute of Scientific and Technical Information of China (English)

周锡山

2013-01-01

在全面论述金圣叹戏曲美学的基础上，着重论述其“天人合一”、“无和梦”、“通鬼神”和“文有魂”等观点。这些重要观点是以儒、道、佛三家的哲学结合其心得体会而论述的，故而取得了精深的成就。金批«西厢»的鉴赏论是针对普通读者的，艺术论是兼顾读者和作家的，美学论是针对文化修养高的欣赏者和作家诗人的；以上美学观点的阐发，则更是针对文化修养极高的鉴赏者和诗人作家的，高深而玄妙，需要长期反复学习、体会才能掌握。%Based on the comprehensive discussion on Jin Shengtan’ s opera aesthetics,the paper focuses on the theory that heaven-man integration,nature and literature creation, nothing and dream, intercommunion with supernatural beings, and the soul in the article. The above views are put forward with combination of Confucianism,Taoism and Buddhism and Jin’ s own stud-y,and accordingly,Jin made profound achievements. Jin’ s appreciation theory on The Romance of West Chamber is aimed at the common readers;his art theory is aimed at both readers and writers; and his aesthetics is aimed at writers and poets with great accomplishments. The paper holds that the explorations of the above aesthetics are aimed at appreciators, writers and poets with great accomplishments,which needs to be repeatedly and further studied.

KANUNISASI FIKIH JINAYAT KONTEMPORER Studi Materi Muatan Qānūn Jināyat Aceh dan Brunei Darussalam

Directory of Open Access Journals (Sweden)

Samsudin Aziz

2014-10-01

Full Text Available This article will view specifically codification of Islamic Criminal Law in `Muslim community, such as Brunei Darussalam, a country based on Islamic principles, and Aceh is a part of Indonesian territory administratively, granted special autonomy to implement Islamic Sharia. Despite having different qualities, -as a country and a province- both have in common as a political power which apply Islamic Criminal Law. Refer to both qānūn jināyat in Brunei and Aceh, the author’ll explain the substance of the criminal law in both area, while also reinforces the implementation of Islamic Criminal Law in the framework of a modern state. The article concludes that basically the application of Islamic Sharia, particularly the Islamic Criminal Law, is closely related to the situation and socio-political conditions of a community or country. The differences of political system, for example, has contributed to the difference in the output of product or policy made by a particular country or territory. On the other hand, Brunei and the Aceh case show that there has been adjustment Islamic Criminal Law specifically set forth in the books of fiqh (as illustration of the Qur'an and Sunnah with the needs of the community itself

Geradeheraus / Matthias Nöther

Index Scriptorium Estoniae

Nöther, Matthias

2008-01-01

Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle. Esietendus 17. oktoobril 2008 Tallinnas Rahvusooperis Estonia

Expression of porcine myosin heavy chain 1 gene in Berkshire loins ...

African Journals Online (AJOL)

Expression of porcine myosin heavy chain 1 gene in Berkshire loins with a high pH24 value. Jin Hun Kang, Woo Young Bang, Eun Jung Kwon, Yong Hwa Lee, Da Hye Park, Eun Seok Cho, Min Ji Kim, Jong-Soon Choi, Hwa Chun Park, Beom Young Park, Chul Wook Kim ...

Piezoelectric Nanogenerators for Self-Powered Nanosystems and Nanosensors

Science.gov (United States)

2013-05-15

researchers 1. Sangmin Lee, Sung-Hwan Bae, Long Lin, Seunghyun Ahn, Chan Park, Seung Nam Cha, Young Jun Park, Hyuk Chang, Sang-Woo Kim and...Sohn, Seung Nam Cha, Dukhyun Choi * Zhong Lin Wang * Sang-Woo Kim * “ P-Type Polymer–Hybridized High-Performance Piezoelectric Nanogenerators”, Nano...Yoon Lee, † Sang-Woo Kim , *,$ Jae-Young Choi, *,† Jong Min Kim , † and Zhong Lin Wang *, “Flexible Hybrid Multi-Type Energy Scavenger”, Energy

Programmed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients

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Zhao Y

2017-12-01

Full Text Available Yu-Jie Zhao,1 Wei-Peng Sun,2 Jian-Hong Peng,1 Yu-Xiang Deng,1 Yu-Jing Fang,1 Jun Huang,2 Hui-Zhong Zhang,3 De-Sen Wan,1 Jun-Zhong Lin,1,* Zhi-Zhong Pan,1,* 1Department of Colorectal Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 2Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, 3Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: Increased expression of programmed death-ligand 1 (PD-L1 on tumor cells can be found in various malignancies; however, very limited information is known about its role in anal squamous cell carcinoma (ASCC. This study explored PD-L1 expression in ASCC patients and its association with patients’ clinicopathological features, CD8+ T cell infiltration, and prognosis.Methods: Formalin-fixed paraffin-embedded tumor samples from 26 patients with ASCC were retrieved. The levels of PD-L1 expression on the membrane of both tumor cells and tumor-infiltrating mononuclear cells (TIMCs were evaluated by immunohistochemistry. CD8+ T cell densities, both within tumors and at the tumor–stromal interface, were also analyzed. Baseline clinicopathological characteristics, human papilloma virus (HPV status, and outcome data correlated with PD-L1-positive staining.Results: PD-L1 expression on tumor cells and TIMCs was observed in 46% and 50% of patients, respectively. Nineteen patients (73% were HPV positive, with 7 showing PD-L1-positive staining on tumor cells and 9 showing PD-L1-positive staining on TIMCs. Increasing CD8+ density within tumors, but not immune stroma, was significantly associated with decreased PD-L1 expression by both tumor cells and TIMCs (P=0.0043 and P=0.0007. Patients with negative PD-L1 expression had significantly better progression-free survival (P=0.038 and P

Zebrafish Model of NF1 for Structure-Function Analysis, Mechanisms of Glial Tumorigenesis, and Chemical Biology

Science.gov (United States)

2015-08-01

models. Zinc-finger nucleases (ZFNs) are chimeric fusions between a zinc-finger protein (ZFP) and the nuclease domain of FokI (Urnov et al., 2010). ZFNs...reference line. Once a target site is chosen, the user can click on the ZFN entry (QueryID; see Fig. 4B) for details about each construct (Fig. 4C...Zhong, Y. (1997). Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuro- peptides . Science 276, 795–798.ports 8, 1265

Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A.

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Diana J M van den Wollenberg

Full Text Available Mammalian Reovirus is a double-stranded RNA virus with a distinctive preference to replicate in and lyse transformed cells. On that account, Reovirus type 3 Dearing (T3D is clinically evaluated as oncolytic agent. The therapeutic efficacy of this approach depends in part on the accessibility of the reovirus receptor Junction Adhesion Molecule-A (JAM-A on the target cells. Here, we describe the isolation and characterization of reovirus T3D mutants that can infect human tumor cells independent of JAM-A. The JAM-A-independent (jin mutants were isolated on human U118MG glioblastoma cells, which do not express JAM-A. All jin mutants harbour mutations in the S1 segments close to the region that encodes the sialic acid-binding pocket in the shaft of the spike protein. In addition, two of the jin mutants encode spike proteins with a Q336R substitution in their head domain. The jin mutants can productively infect a wide range of cell lines that resist wt reovirus T3D infection, including chicken LMH cells, hamster CHO cells, murine endothelioma cells, human U2OS and STA-ET2.1 cells, but not primary human fibroblasts. The jin-mutants rely on the presence of sialic-acid residues on the cell surface for productive infection, as is evident from wheat germ agglutinin (WGA inhibition experiments, and from the jin-reovirus resistance of CHO-Lec2 cells, which have a deficiency of sialic-acids on their glycoproteins. The jin mutants may be useful as oncolytic agents for use in tumors in which JAM-A is absent or inaccessible.

X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots ...

Indian Academy of Sciences (India)

Astr. (2011) 32, 193–196 c Indian Academy of Sciences. X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots and Knots in AGN Jets. Jin Zhang1,∗. , Jin-Ming Bai2, Liang Chen2 & Enwei Liang3. 1College of Physics and Electronic Engineering, Guangxi Teachers Education University,. Nanning 530001, China.

JPRS Report, China, Maos Legacy in Anhui, Rural Reform 1978-80.

Science.gov (United States)

1989-07-28

boil some noodles , and then asked Zhan Shaozhou: "What brought you here?" "To report to you!" "Report what?" "It has begun. More is being done...policy of looking after serious disaster areas on holidays, providing each person with 3 jin of rice, 2 jin of noodles , and xh jin of meat. They went...abandon for an instant ! Chapter 6. A Tragedy Not To Be Repeated—1980: The Great Anhui Flood History Continues To Testify 1 The Earth, which nurtures us

A rapid and highly sensitive protocol for the detection of Escherichia coli O157:H7 based on immunochromatography assay combined with the enrichment technique of immunomagnetic nanoparticles

Directory of Open Access Journals (Sweden)

Qi H

2011-11-01

Full Text Available Hui Qi1, Zhen Zhong1, Han-Xin Zhou1, Chun-Yan Deng1, Hai Zhu2, Jin-Feng Li2, Xi-Li Wang2, Fu-Rong Li1,31Clinical Medical Research Center, The Second Clinical Medical College (Shenzhen People's Hospital, Jinan University, 2Shenzhen Bioeasy Biotechnologies Co, Ltd, 3Shenzhen Institute of Gerontology, Shenzhen, People's Republic of ChinaBackground: Escherichia coli O157:H7 (E. coli O157:H7 is an important pathogenic bacterium that threatens human health. A rapid, simple, highly sensitive, and specific method for the detection of E. coli O157:H7 is necessary.Methods: In the present study, immunomagnetic nanoparticles (IMPs were prepared with nanopure iron as the core, coated with E. coli O157:H7 polyclonal antibodies. These IMPs were used in combination with immunochromatographic assay (ICA and used to establish highly sensitive and rapid kits (IMPs+ICA to detect E. coli O157:H7. The kits were then used to detect E. coli O157:H7 in 150 food samples and were compared with conventional ICA to evaluate their efficacy.Results: The average diameter of IMPs was 56 nm and the amount of adsorbed antibodies was 106.0 µg/mg. The sensitivity of ICA and IMPs+ICA was 105 colony-forming units/mL and 103 CFUs/mL, respectively, for purified E. coli O157:H7 solution. The sensitivity of IMPs+ICA was increased by two orders, and its specificity was similar to ICA.Conclusion: The kits have the potential to offer important social and economic benefits in the screening, monitoring, and control of food safety.Keywords: colloidal gold, immunomagnetic nanoparticles, Escherichia coli O157:H7, immunochromatographic assay

Journal of Astrophysics and Astronomy | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Astrophysics and Astronomy. Liu Zhong-Bao. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 2 June 2016 pp 12. Stellar Spectral Classification with Locality Preserving Projections and Support Vector Machine · Liu Zhong-bao · More Details Abstract Fulltext PDF.

Pediatric Palliative Care: A Personal Story

Medline Plus

Full Text Available ... Duration: 23:09. Matthias 1,036,758 views New 23:09 Language: English Location: United States Restricted ... YouTube Terms Privacy Policy & Safety Send feedback Test new features Loading... Working... Sign in to add this ...

76 FR 19033 - Action Affecting Export Privileges; Credit International Trading Co. Ltd; In the Matter of...

Science.gov (United States)

2011-04-06

... Zhong Guan Cun Nan Street, Haidian District, Beijing 100039, People's Republic of China and No 9A Dongtucheng Road, Heping Street, Chaoyang District, Beijing, People's Republic of China; Order Making Order.... 2 Zhong Guan Cun Nan Street, Haidian District, Beijing 100039, People's Republic of China, and No 9A...

Missionary Medicine of Canadian Presbytery and Korean Doctors under Japanese Occupation - focusing Sung-jin and Ham-heung

Directory of Open Access Journals (Sweden)

Yun-Jung HEO

2015-12-01

Full Text Available In East Asia during the second half of the 19th century, overseas mission work by Protestant churches thrived. Missionaries built schools and hospitals and effectively used them for evangelism. In the 20th century when Social Gospel Movement was expanding, medical work has been recognized as a significant mission service in and by itself. This article reviewed the construction and characteristics of missions work conducted by Canadian Presbytery; missionary doctors and Korean doctors who worked at the mission hospitals; why the missionary medical work had to stop; and career paths taken by Korean doctors upon liberation from Japanese occupation. The Canadian Presbytery missionaries, unlike other denomination missionaries, were rather critical of Imperial Japan, but supportive towards Koreans. This could have stemmed from the reflection of their own experience of once a colony of British Empire and also their value system that promotes egalitarian, democratic and progressive theology. The Sung-jin and Ham-heung Mission Bases were a community, interacting organically as a ‘Triangle of Church, School and Hospital.’ The missionaries mobilized the graduates from Christian schools and organized a Young Men’s Christian Association (YMCA. Some of the graduates were trained to become medical doctors or assistants and worked at mission hospitals. Missionary doctors’ approaches to balancing evangelism and medical practice varied. For example, Robert Grieson went through confusion and struggled to balance conflicting roles as a pastor for evangelism and also as a physician. Kate McMillan, on the other hand, had less burden for evangelism than Grieson, and focused on medical work by taking advantage of the opportunity that, as a woman, she can easily approach Korean women. Still another case was Florence Murray who practised evangelism within the hospital setting, and successfully carried out the role as a hospital administrator, going beyond �

[Missionary Medicine of Canadian Presbytery and Korean Doctors under Japanese Occupation--focusing Sung-jin and Ham-heung].

Science.gov (United States)

Heo, Yun-Jung; Cho, Young-Soo

2015-12-01

In East Asia during the second half of the 19th century, overseas mission work by Protestant churches thrived. Missionaries built schools and hospitals and effectively used them for evangelism. In the 20th century when Social Gospel Movement was expanding, medical work has been recognized as a significant mission service in and by itself. This article reviewed the construction and characteristics of missions work conducted by Canadian Presbytery; missionary doctors and Korean doctors who worked at the mission hospitals; why the missionary medical work had to stop; and career paths taken by Korean doctors upon liberation from Japanese occupation. The Canadian Presbytery missionaries, unlike other denomination missionaries, were rather critical of Imperial Japan, but supportive towards Koreans. This could have stemmed from the reflection of their own experience of once a colony of British Empire and also their value system that promotes egalitarian, democratic and progressive theology. The Sung-jin and Ham-heung Mission Bases were a community, interacting organically as a 'Triangle of Church, School and Hospital.' The missionaries mobilized the graduates from Christian schools and organized a Young Men's Christian Association (YMCA). Some of the graduates were trained to become medical doctors or assistants and worked at mission hospitals. Missionary doctors' approaches to balancing evangelism and medical practice varied. For example, Robert Grieson went through confusion and struggled to balance conflicting roles as a pastor for evangelism and also as a physician. Kate McMillan, on the other hand, had less burden for evangelism than Grieson, and focused on medical work by taking advantage of the opportunity that, as a woman, she can easily approach Korean women. Still another case was Florence Murray who practised evangelism within the hospital setting, and successfully carried out the role as a hospital administrator, going beyond 'women's work' as McMillan did

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. ZHONG DU1 BO TIAN1 XI-YANG XIE1 JUN CHAI1 XIAO-YU WU1. State Key Laboratory of Information Photonics and Optical Communications, and School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China ...

TERT-CLPTM1 locus polymorphism (rs401681) is associated with the prognosis of hepatocellular carcinoma

OpenAIRE

Lee, Hye Won; Park, Won-Jin; Heo, Yu-Ran; Park, Tae In; Park, Soo Young; Lee, Jae-Ho

2017-01-01

Hye Won Lee,1,* Won-Jin Park,2,* Yu-Ran Heo,2 Tae In Park,3 Soo Young Park,4 Jae-Ho Lee2,* 1Department of Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; 2Department of Anatomy, Keimyung University School of Medicine, Daegu, Republic of Korea; 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 4Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea *T...

Dissecting and Targeting Latent Metastasis

Science.gov (United States)

2014-09-01

Option in Brain Metastasis Manuel Valiente,1 Anna C. Obenauf,1 Xin Jin,1 Qing Chen,1 Xiang H.-F. Zhang,1,8 Derek J. Lee,1 Jamie E. Chaft,2 Mark G. Kris,2...of poor response to tamoxifen therapy in recurrent breast cancer. J. Natl. Cancer Inst. 87, 751–756. Francia, G., Cruz -Munoz, W., Man, S., Xu, P... Manuel Valiente1, Xin Jin1†, Ekrem Emrah Er1, Ruzeen Patwa1, Ke Xu3 and Joan Massagué1 1 Cancer Biology and Genetics Program, 2 Department of

RMIT at the TREC 2015 LiveQA Track

Science.gov (United States)

2015-11-20

recipient of an Australian Research Council DECRA Research Fellowship (DE140100275). REFERENCES [1] Michael Collins. Head-driven statistical models for...18th Australasian Document Computing Symposium, pages 58–65. ACM, 2013. [4] Matthias Petri, Alistair Moffat, and J Shane Culpepper. Score-safe term

Retraction RETRACTION of "Methylation of the RASSFIA promoter in breast cancer" by Y. Ji, H.H. Jin, M.D. Wang, W.X. Cao, J.L. Bao - Genet. Mol. Res. 15 (2): gmr.15028261 (2016) - DOI: 10.4238/gmr.15028261.

Science.gov (United States)

Ji, Y; Jin, H H; Wang, M D; Cao, W X; Bao, J L

2016-10-07

The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that are copied from "Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome", by Jia Xu, Priya B Shetty, Weiwei Feng, Carol Chenault, Robert C Bast Jr, Jean-Pierre J Issa, Susan G Hilsenbeck and Yinhua Yu, published in BMC Cancer 2012; 12: 243. DOI: 10.1186/1471-2407-12-243. The first paragraphs of both discussions are identical. This is concerning. The abstract and introduction sections have much of their text plagiarized. Overall, there is high plagiarism detected. The GMR editorial staff was alerted and after a thorough investigation, we have strong reason to believe that the peer review process was failure and, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract the article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.

Barriers to the adoption of energy-saving technologies in the building sector: A survey study of Jing-jin-tang, China

International Nuclear Information System (INIS)

Du, Ping; Zheng, Li-Qun; Xie, Bai-Chen; Mahalingam, Arjun

2014-01-01

The building sector of China currently consumes 20% of the total energy consumption. Studies on barriers to the adoption of building energy-saving technologies are of great significance on implementing policies related to achieving energy-saving goals. This paper studied 15 barriers with the aid of information collected through questionnaires and semi-structured interviews. The respondents were 135 employees working in the Jing-jin-tang area. Based on the results of the factor analysis, the barriers were categorized into five groups: attitudes of stakeholders, policies and regulations, auxiliary resources, profitability, and adaptability of the technologies. Analysis of the entire sample showed that the stakeholders’ reluctance to use was the largest barrier, followed by high initial investment and low profitability. Further analysis showed that the occupation and designation of the respondents and the size of the enterprises that they served influenced their perspectives on the barriers. It was found that architects attributed more importance to the adoption of energy-saving technologies than contractors; barriers confronted by employees of large enterprises and small enterprises were different; managers perceived weaker barriers than frontline employees and were more optimistic about the prospect of building energy-saving technologies. Finally, policy recommendations were proposed based on these in-depth and targeted analyses. - Highlights: • Fifteen barriers to the adoption of energy-saving technologies are discussed. • Surveys are conducted in one of China's most technologically developed area. • The barriers are divided into 5 groups according to the results of factor analysis. • Barriers related to profitability greatly hamper the adoption of the technologies. • Comparative analyses show the background of respondents influence their viewpoints

Besifloxacin: a novel anti-infective for the treatment of bacterial conjunctivitis

Directory of Open Access Journals (Sweden)

Timothy L Comstock

2010-03-01

Full Text Available Timothy L Comstock1, Paul M Karpecki2, Timothy W Morris3, Jin-Zhong Zhang41Global Medical Affairs, Pharmaceuticals, Bausch and Lomb, Inc., Rochester, NY, USA; 2Koffler Vision Group, Lexington, KY, USA; 3Research and Development Microbiology and Sterilization Sciences, Bausch and Lomb, Inc., Rochester, NY, USA; 4Global Preclinical Development, Bausch and Lomb, Inc., Rochester, NY, USAAbstract: Bacterial conjunctivitis, commonly known as pink eye, is demographically unbiased in its prevalence and can be caused by a variety of aerobic and anaerobic bacteria. Timely empiric treatment with a broad-spectrum anti-infective, such as a topical fluoroquinolone, is critical in preventing potentially irreversible ocular damage. However, the rise in ocular methicillin-resistant Staphylococcus aureus isolates and the patterns of fluoroquinolone resistance for patients with other ocular bacterial infections mandate the need for new agents targeted for ocular use. Besifloxacin, a novel broad-spectrum fluoroquinolone, is approved for the treatment of bacterial conjunctivitis. It has a uniquely balanced dual-targeting activity that inhibits both DNA gyrase and topoisomerase IV and is associated with a lower incidence of resistance development. Besifloxacin is not marketed in other formulations, ensuring that its exposure is limited to bacterial populations in and around the eye. This specifically precludes any bacterial exposure to besifloxacin resulting from systemic use, which further reduces the likelihood of emergence of bacterial resistance. In vitro, besifloxacin has demonstrated equivalent or superior activity compared with other commonly used topical antibiotics. In clinical trials, besifloxacin has consistently demonstrated efficacy and safety in the treatment of patients with bacterial conjunctivitis. Besifloxacin is considered safe and is well tolerated with no observed contraindications.Keywords: conjunctivitis, fluoroquinolones, besifloxacin

Li et al., Afr J Tradit Complement Altern Med. (2013) 10(5):375-379 ...

African Journals Online (AJOL)

cadewumi

-gang, Zhao Jin-ning, Wang Zhi, Li Jin. (2004). Effects of Total Flavone from Drynaria Fortunei on Bone. Density and IL-6, IL-4 and TNFα Levels in Ovariectomized Rats. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 01:.

Establishing the potential dependent equilibrium oxide coverage on platinum in alkaline solution and its influence on the oxygen reduction

DEFF Research Database (Denmark)

Wiberg, Gustav; Arenz, Matthias

2012-01-01

Publication year: 2012 Source:Journal of Power Sources, Volume 217 Gustav K.H. Wiberg, Matthias Arenz The oxidation process of polycrystalline platinum subjected to alkaline solution is re-examined using a combination of cyclic voltammetry and potential hold techniques in Ar, H2 and O2 purged 0.1...

Fine mapping of a dominantly inherited powdery mildew resistance major-effect QTL, Pm1.1, in cucumber identifies a 41.1 kb region containing two tandemly arrayed cysteine-rich receptor-like protein kinase genes.

Science.gov (United States)

Xu, Xuewen; Yu, Ting; Xu, Ruixue; Shi, Yang; Lin, Xiaojian; Xu, Qiang; Qi, Xiaohua; Weng, Yiqun; Chen, Xuehao

2016-03-01

A dominantly inherited major-effect QTL for powdery mildew resistance in cucumber was fine mapped. Two tandemly arrayed cysteine-rich receptor-like protein kinase genes were identified as the most possible candidates. Powdery mildew (PM) is one of the most severe fungal diseases of cucumber (Cucumis sativus L.) and other cucurbit crops, but the molecular genetic mechanisms of powdery mildew resistance in cucurbits are still poorly understood. In this study, through marker-assisted backcrossing with an elite cucumber inbred line, D8 (PM susceptible), we developed a single-segment substitution line, SSSL0.7, carrying 95 kb fragment from PM resistance donor, Jin5-508, that was defined by two microsatellite markers, SSR16472 and SSR16881. A segregating population with 3600 F2 plants was developed from the SSSL0.7 × D8 mating; segregation analysis confirmed a dominantly inherited major-effect QTL, Pm1.1 in cucumber chromosome 1 underlying PM resistance in SSSL0.7. New molecular markers were developed through exploring the next generation resequenced genomes of Jin5-508 and D8. Linkage analysis and QTL mapping in a subset of the F2 plants delimited the Pm1.1 locus into a 41.1 kb region, in which eight genes were predicted. Comparative gene expression analysis revealed that two concatenated genes, Csa1M064780 and Csa1M064790 encoding the same function of a cysteine-rich receptor-like protein kinase, were the most likely candidate genes. GFP fusion protein-aided subcellular localization indicated that both candidate genes were located in the plasma membrane, but Csa1M064780 was also found in the nucleus. This is the first report of dominantly inherited PM resistance in cucumber. Results of this study will provide new insights into understanding the phenotypic and genetic mechanisms of PM resistance in cucumber. This work should also facilitate marker-assisted selection in cucumber breeding for PM resistance.

Silicon improves salt tolerance by increasing root water uptake in Cucumis sativus L.

Science.gov (United States)

Zhu, Yong-Xing; Xu, Xuan-Bin; Hu, Yan-Hong; Han, Wei-Hua; Yin, Jun-Liang; Li, Huan-Li; Gong, Hai-Jun

2015-09-01

Silicon enhances root water uptake in salt-stressed cucumber plants through up-regulating aquaporin gene expression. Osmotic adjustment is a genotype-dependent mechanism for silicon-enhanced water uptake in plants. Silicon can alleviate salt stress in plants. However, the mechanism is still not fully understood, and the possible role of silicon in alleviating salt-induced osmotic stress and the underlying mechanism still remain to be investigated. In this study, the effects of silicon (0.3 mM) on Na accumulation, water uptake, and transport were investigated in two cucumber (Cucumis sativus L.) cultivars ('JinYou 1' and 'JinChun 5') under salt stress (75 mM NaCl). Salt stress inhibited the plant growth and photosynthesis and decreased leaf transpiration and water content, while added silicon ameliorated these negative effects. Silicon addition only slightly decreased the shoot Na levels per dry weight in 'JinYou 1' but not in 'JinChun 5' after 10 days of stress. Silicon addition reduced stress-induced decreases in root hydraulic conductivity and/or leaf-specific conductivity. Expressions of main plasma membrane aquaporin genes in roots were increased by added silicon, and the involvement of aquaporins in water uptake was supported by application of aquaporin inhibitor and restorative. Besides, silicon application decreased the root xylem osmotic potential and increased root soluble sugar levels in 'JinYou 1.' Our results suggest that silicon can improve salt tolerance of cucumber plants through enhancing root water uptake, and silicon-mediated up-regulation of aquaporin gene expression may in part contribute to the increase in water uptake. In addition, osmotic adjustment may be a genotype-dependent mechanism for silicon-enhanced water uptake in plants.

International Conference on Organometallic Chemistry (13th) Held in Torino, Europe on 4-9 September 1988. Abstracts

Science.gov (United States)

1988-09-09

190, 8057 ZUrich, Switzerland Joseph Edwin and William E.Geiger, Department of Chemistry, University of Vermont, Burlington, Vermont, 05405 Arnold L...On Synthesis Of Dialkyl d-Trimethylsilyloxyalkylphosphonates Zhao Yong-Zhen and Li Zhong- Rua Dpartment o chemistry, Hua Zhong Normal University, Wuhan...Jose Vicente. Jose-AntelC hAd. Na-Yeij~xa Qhicote. Ju~an-Francisco Gutliez-Jugo. Carmen Ramirez do Arel lano. Departamento do Oulmica InordanIca

The Chinese Armed Forces in the 21st Century

Science.gov (United States)

1999-12-01

161-162; and Liu Mingtao and Yang Chengjun, Gao jushu zhanzheng zhong de daodan zhan (Missile Wars During High Tech Warfare), Beijing : Guofang daxue ...Guofang daxue chubanshe, 1996; Wang Pufeng, ed., Mao Zedong junshi zhanlue lun {On Mao Zedong’s Military Strategy), Beijing : Junshi kexue chubanshe...Science, Technology and Industry), Beijing : Guofang gongye chubanshe, pp. 157-159; Wu Jianguo, "Gaojishu zhanzheng zhong de he yinying bu rong

Holomorphic two-spheres in the complex Grassmann manifold G (k, n)

Indian Academy of Sciences (India)

Author Affiliations. Xiaoxiang Jiao1 Xu Zhong1 Xiaowei Xu2. School of Mathematical Sciences, Graduate University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China; Department of Mathematics, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China ...

Proceeding of the 1999 Particle Accelerator Conference. Volume 1

Science.gov (United States)

1999-04-02

Instituto De Fisica Da Universidade De Sijo Paulo, Brazil; F.T.Degasperi, Faculdade De Tecnologia De Silo Paulo, Brazil...1524 Methods and Complex of Programs for Radiating Particle 3D of Nonlinear Dynamics Analysis -- Y.Alexahin, JIN R , D ubna, R ussia...1623 3d Multispecies Nonlinear Perturbative Particle Simulation of Intense Particle Beams -- Hong

Structure analysis and core community detection of embodied resources networks among regional industries

Science.gov (United States)

He, Xijun; Dong, Yanbo; Wu, Yuying; Wei, Guodan; Xing, Lizhi; Yan, Jia

2017-08-01

To address the double pressure of scarce resources and regional industrial isomorphism, this paper applied the concepts of exergy and embodied resources based on economic input-output (I-O) data. We constructed the embodied resources networks among the regional industries of Beijing-Tianjin-Hebei (also known as Jing-Jin-Ji) in China. We analyzed the rules of embodied resources consumption in the area's industries, identified the core community structures, and studied the characteristics of industrial homogeneity through regional comparisons. The results showed that the dependence on scarce resources of industrial operations in Beijing was less than in Jin-Ji, while the dependence on finance, technology, information, and other service resources in Beijing was higher than in Jin-Ji. The I-O efficiency of embodied resources among industries and the agglomeration of correlation relationships in industries with large embodied resources were higher than in Jin-Ji. The industrial coincidence degree in the ;bridge; industries and in the core community in Jin-Ji was higher than in Jing-Jin and Jing-Ji, which means the industrial homogeneous competition of Jin-Ji was higher, too. This study makes a significant contribution toward promoting the dislocation development of regional industries, accelerating the coordination of resources, and reducing homogeneity competition.

Strengthening the case that elevated levels of programmed death ligand 1 predict poor prognosis in hepatocellular carcinoma patients

Directory of Open Access Journals (Sweden)

Zhong J

2016-12-01

Full Text Available Jian-Hong Zhong,1,* Cheng-Piao Luo,2,* Chun-Yan Zhang,2 Le-Qun Li1 1Hepatobiliary Surgery Department, 2Experimental Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, People’s Republic of China *These authors contributed equally to this work Abstract: Immunotherapy targeting programmed death receptor 1 and programmed death ligand 1 (PD-L1 has shown impressive antitumor efficacy in several solid cancers, including advanced hepatocellular carcinoma (HCC. Since response rates of various cancers to such immunotherapy appear to correlate with PD-L1 expression levels, several studies have examined whether PD-L1 expression correlates with HCC pathology and patient prognosis. In this paper, we analyzed the strength and limitations of a recent meta-analysis of associations of PD-L1 with HCC characteristics and patient prognosis. Keywords: hepatocellular carcinoma, programmed death ligand 1, hepatic resection, prognoses

The first genetic linkage map of Eucommia ulmoides

Indian Academy of Sciences (India)

Eucommia ulmoides Oliv., also called Du-Zhong, is the .... The polymorphic markers were analysed by a chi-square test ... ratio of a dominant locus in an F1 population (P < 0.05). ..... loss, viability per lethal genes, genetic isolation mech-.

c-Fos expression in the paternal mouse brain induced by communicative interaction with maternal mates

OpenAIRE

鍾, 静; Zhong, Jing

2014-01-01

博士論文要旨Abstract 以下に掲載：Molecular Brain 7(66) pp.1-11 2014. BioMed Central. 共著者：Jing Zhong, Mingkun Liang, Shirin Akther, Chiharu Higashida, Takahiro Tsuji, Haruhiro Higashida

Matter-wave bright solitons in effective bichromatic lattice potentials

Indian Academy of Sciences (India)

2013-08-01

Aug 1, 2013 ... M Theis, G Thalhammer, K Winkler, M Hellwig, G Ruff, R Grimm and J H Denschlag, Phys. Rev. Lett. 93, 123001 (2004). [11] Gregor Thalhammer, Matthias Theis, Klaus Winkler, Rudolf Grimm and Johannes Hecker. Denschlag, Phys. Rev. A 71, 033403 (2005). [12] H Sakaguchi and B A Malomed, Phys.

Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy

OpenAIRE

Unterweger, Harald; Subatzus, Daniel; Tietze, Rainer; Janko, Christina; Poettler, Marina; Stiegelschmitt, Alfons; Schuster, Matthias; Maake, Caroline; Boccaccini, Aldo R; Alexiou, Christoph

2015-01-01

Harald Unterweger,1 Daniel Subatzus,1 Rainer Tietze,1 Christina Janko,1 Marina Poettler,1 Alfons Stiegelschmitt,2 Matthias Schuster,3 Caroline Maake,4 Aldo R Boccaccini,5 Christoph Alexiou11ENT Department, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung Professorship, University Hospital Erlangen; 2Institute of Glass and Ceramics, Department of Materials Science and Engineering, University Erlangen-Nuremberg, 3Materials for Electronics and Ene...

Private visit to the CMS assembly site of Dr. Fidel Castro Diaz-Balart from the Superior Institute of Sciences and Nuclear Technologies, Havana, accompanied by His Excellency Mr. Emilio Caballero, Ambassador, Permanent Mission of Cuba in Paris.

CERN Multimedia

Maximilien Brice

2002-01-01

Photo 01: Left to right: His Excellency Mr Emilio Caballero; Prof. Tejinder Virdee, Deputy Spokesman of the CMS experiment; Dr Fidel Castro Diaz-Balart; Dr Matthias Schroeder, physicist, Experimental Physics division; Mrs Noëlle Levy, Casa del Habano, Geneva; Dr John Ellis, Adviser for Non-Member State relations; Dr Christian Roche, Senior Advisor to the Director-General. Photo 02: Left to right: His Excellency Mr Emilio Caballero, Prof. Tejinder Virdee, Dr Fidel Castro Diaz-Balart; Dr Matthias Schroeder; Mrs Noëlle Levy, Prof. Juan Antonio Rubio, Head of the Education and Technology Transfer division; Dr John Ellis.

The future of bioenergy; Die Zukunft der Bioenergie

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-07-01

This volume contains the following five contributions: 1. The impact of the governmental biogas production on agricultural rents in Germany. An econometric study (Hendrik Garvert); 2. Biogas as price drivers on the land and rental market? An Empirical Analysis (Uwe Latacz-Lohmann); 3. Analysis of comparative advantage of bioenergy in electricity and heat production. Greenhouse gas abatement and mitigation costs in Brandenburg (Lukas Scholz); 4. Flexibility potential of biogas and biomethane CHP in the investment portfolio (Matthias Edel); 5. Legal possibilities and limitations of a reform of the system for the promotion of bioenergy (Jose Martinez). [German] Dieser Band enthaelt folgende fuenf Themenbeitraege: 1. Die Auswirkungen der staatlichen Biogasfoerderung auf landwirtschaftliche Pachtpreise in Deutschland. Eine oekonometrische Untersuchung (Hendrik Garvert); 2. Biogas als Preistreiber am Bodenmarkt und Pachtmarkt? Eine empirische Analyse (Uwe Latacz-Lohmann); 3. Analyse komparativer Kostenvorteile von Bioenergielinien in der Strom- und Waermeproduktion Treibhausgasvermeidung und Vermeidungskosten in Brandenburg (Lukas Scholz); 4. Flexibilisierungspotenzial von Biogas- und Biomethan-BHKWs im Anlagenbestand (Matthias Edel); 5. Rechtliche Moeglichkeiten und Grenzen einer Reform des Systems zur Foerderung der Bioenergie (Jose Martinez).

Multiscale Numerical Methods for Non-Equilibrium Plasma

Science.gov (United States)

2015-08-01

Smith Chris Anderson Xiaolin Zhong Jean-Luc Cambier Ann Karagozian, Committee Chair University of California, Los Angeles 2012 iv E-7 To my mother...of my committee, Professor Xiaolin Zhong and Professor Chris Anderson, for their guidance. I would like to thank my current and past labmates, Chris ...detonations. Phys. Fluids, 15:112–122, 2003. 221 E-246 [15] H. D. Ng, A. J. Higgins , C. B. Kiyanda, M. I. Radulescu, J. H. S. Lee, K. R. Bates, and N

DNA characterization and polymorphism of KISS1 gene in Egyptian ...

African Journals Online (AJOL)

Aghomotsegin

2015-07-29

Jul 29, 2015 ... effect on litter size performance and many studies were carried out to identify ... gene (Wang et al., 2011), kit ligand (KITLG) gene (An et al., 2012) and bone ..... An XP, Han P, HouJX, Zhao HB, Yan Y, Ma T, Fang F, MengFX, Song. YX, Wang JG ... Chu MX, Zhao XH, Zhang YJ, Jin M (2010). Polymorphisms ...

The Optimal Technological Development Path to Reduce Pollution and Restructure Iron and Steel Industry for Sustainable Transition

OpenAIRE

Ren, M.; Xu, X.; Ermolieva, T.; Cao, G.-Y.; Yermoliev, Y.

2018-01-01

China is the world’s largest iron and steel producer and Jing-Jin-Ji (Beijing-Tianjin-Hebei) region accounts for nearly 1/3 of the national iron and steel production, while it is facing serious air pollution. Among the top 10 worst polluted cities in China, seven were located in Hebei province in 2014. Recent years Jing-Jin-Ji region has been promoted iron & steel industry with green clean technology for accelerating sustainable economic transition. This paper tries to response the basic ques...

Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

CSIR Research Space (South Africa)

Zimmermann, S

2014-03-01

Full Text Available Stefanie Zimmermann 1,2, Gerda Fouché 3, Maria De Mieri 1, Yukiko Yoshimoto 4, Toyonobu Usuki 4, Rudzani Nthambeleni 3, Christopher J. Parkinson 5, Christiaan van der Westhuyzen 3, Marcel Kaiser 2,6, Matthias Hamburger 1 and Michael Adams 1,* 1... 1. Introduction Sleeping sickness, or human African trypanosomiasis (HAT), is a deadly protozoal disease caused by Trypanosoma brucei species spread by tsetse flies (Glossina spp.). The two human pathogenic subspecies, T. b. rhodesiense (95...

Therapeutic deep brain stimulation worsening dysprosody in Parkinson’s disease – an unexplored entity

Directory of Open Access Journals (Sweden)

Shoaib M

2018-03-01

Full Text Available Maria Shoaib,1 Muhammad Taimoor Khan2 1Department of Medicine, Dow Medical College, Karachi, Pakistan; 2Department of Neurology, Charleston Area Medical Center/West Virginia University, Charleston, WV, USA  We read this article, “Altered emotional recognition and expression in patients with Parkinson’s disease” by Jin et al1 with great interest and appreciate the novel information provided on altered emotional processing in pre-deep brain stimulation (DBS Parkinson’s disease (PD patients and we would like to add our feedback on the role of DBS on nonmotor and emotional components of PD.View the original paper by Jin and colleagues. 

Umfrageforschung: Entscheidungsgrundlage für Politik und Wissenschaft

OpenAIRE

2011-01-01

"Der vorliegende Tagungsband dokumentiert die Beiträge der wissenschaftlichen Tagung 'Umfrageforschung - Entscheidungsgrundlage für Politik und Wissenschaft', die am 30. Juni und 1. Juli 2011 gemeinsam vom Statistischen Bundesamt, dem ADM Arbeitskreis Deutscher Markt- und Sozialforschungsinstitute e.V. und der Arbeitsgemeinschaft Sozialwissenschaftlicher Institute e.V. (ASI) in Wiesbaden durchgeführt wurde." (Autorenreferat). Inhaltsverzeichnis: Christian König, Matthias Stahl, Erich Wiegand:...

[Surveys on resources and varieties on Chinese markets of crude drug mahuang].

Science.gov (United States)

Hong, Hao; Chen, Hubiao; Xu, Feng; Zang, Xinyu; Yang, Donghui; Wang, Xuan; Cai, Shaoqing; Mikage, Masayuki

2011-05-01

Many species of the genus Ephedra plants are used as Chinese traditional medicines, in Chinese which are known as "Mahuang" (Ephedrae Herba). In order to get a clear picture of resources distribution and varieties on Chinese markets of the crude drug Mahuang and provide scientific basis for their resource conservation and sustainable use, during recent years we conducted field investigations and market researches many times. The results showed that the most common species on the Chinese markets was E. sinica (33/38 commercial samples), followed by E. intermedia (5/38 commercial samples), which was also used in local clinics in Qing-hai, Gansu and Xinjiang province, no E. equisetina was found in the market. We noticed that the resources of both official and non-official plants of Mahuang, especially Zhong-Mahuang and Muzei-Mahuang, were seriously damaged in the past decade because of the ecological environment damage and over-digging. Zhong-Mahuang was distinguished in Ningxia and north Gansu, which was once one of the most distribution areas and contains more than 10,000 t Zhong-Mahuang. Muzei-Mahuang was distinguished in most places and distributed sparsely around Altay Mountains in northeast in Xinjiang. Thus, Cultivation of Mahuang, especially Zhong-Mahuang and Muzei-Mahuang should be greatly developed. At the same time, wild resources of Mahuang must be preserved strictly, i.e., proper method of cutting Ephedra plant could prevent the damage of the resource.

Joint Institute for Nanoscience Annual Report 2004

Energy Technology Data Exchange (ETDEWEB)

Baer, Donald R.; Campbell, Charles

2005-02-01

Due to the inherently interdisciplinary nature of nanoscience and nanotechnology, research in this arena is often significantly enhanced through creative cooperative activities. The Joint Institute for Nanoscience (JIN) is a venture of the University of Washington (UW) and Pacific Northwest National Laboratory (PNNL) to encourage and enhance high impact and high quality nanoscience and nanotechnology research that leverages the strengths and capabilities of both institutions, and to facilitate education in these areas. This report summarizes JIN award activities that took place during fiscal year 2004 and provides a historical list of JIN awardees, their resulting publications, and JIN-related meetings. Major portions of the JIN efforts and resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by PNNL staff scientists and UW professors. JIN fellowships are awarded on the basis of applications that include research proposals. They have been very successful in expanding collaborations between PNNL and UW, which have led to many excellent joint publications and presentations and enhanced the competitiveness of both institutions for external grant funding. JIN-based interactions are playing a significant role in creating new research directions and reshaping existing research programs at both the UW and PNNL. The JIN also co-sponsors workshops on Nanoscale Science and Technology, four of which have been held in Seattle and one in Richland. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant, Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology, has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the University of

A functional SNP upstream of the ADRB2 gene is associated with COPD

Directory of Open Access Journals (Sweden)

Li JX

2018-03-01

Full Text Available Jin-Xiu Li,1,2,* Wei-Ping Fu,3,* Jing Zhang,4 Xiao-Hua Zhang,1,2 Chang Sun,1,5 Lu-Ming Dai,3 Li Zhong,1,5,6 Li Yu,1,2 Ya-Ping Zhang1,7 1State Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan, 2Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, School of Life Sciences, Yunnan University, 3Department of Respiratory Critical Care Medicine, 4Department of Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, 5College of Life Sciences, 6Provincial Demonstration Center for Experimental Biology Education, Shaanxi Normal University, Xi’an, 7State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China *These authors contributed equally to this work Background: Previous studies have suggested that β2-adrenergic receptor (ADRB2 is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods: In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reaction were adopted to investigate the association between ADRB2 genetic polymorphisms and COPD, comprehensively. Results: One single nucleotide polymorphism (rs12654778, located upstream of ADRB2, showed a significant association with COPD by the logistic regression analysis after adjusting for age, sex and smoking history (p=0.04 in 200 COPD patients and 222 controls from southwest Chinese population. Furthermore, the luciferase assay indicated that rs12654778-A allele reduced the relative promoter activity by ~26% compared with rs12654778-G allele (p=0.0034. The chromatin immunoprecipitation analysis demonstrated that rs12654778 modulated the binding affinity of transcription factor neurofibromin 1. In addition, a significantly reduced expression of ADRB

CDEX-1 1 kg point-contact germanium detector for low mass dark matter searches

International Nuclear Information System (INIS)

Kang Kejun; Yue Qian; Wu Yucheng

2013-01-01

The CDEX collaboration has been established for direct detection of light dark matter particles, using ultra-low energy threshold point-contact p-type germanium detectors, in China JinPing underground Laboratory (CJPL). The first 1 kg point-contact germanium detector with a sub-keV energy threshold has been tested in a passive shielding system located in CJPL. The outputs from both the point-contact P + electrode and the outside N + electrode make it possible to scan the lower energy range of less than 1 keV and at the same time to detect the higher energy range up to 3 MeV. The outputs from both P + and N + electrode may also provide a more powerful method for signal discrimination for dark matter experiment. Some key parameters, including energy resolution, dead time, decay times of internal X-rays, and system stability, have been tested and measured. The results show that the 1 kg point-contact germanium detector, together with its shielding system and electronics, can run smoothly with good performances. This detector system will be deployed for dark matter search experiments. (authors)

Saturation mapping of QTL region determining resistance specificity ...

African Journals Online (AJOL)

STORAGESEVER

2009-09-01

Sep 1, 2009 ... S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J,. Hong G, Xue Y, Han B ... Katagiri F, Markus Lange B, Moughamer T, Xia Y, Budworth P,. Zhong J, Miguel T, ... Gen. Genet. 261: 58-63. Marrs KA (1996).

Economic Growth and Sustainable Housing: An Uneasy Relationship

DEFF Research Database (Denmark)

Buch-Hansen, Hubert

2017-01-01

Book review of: "Economic Growth and Sustainable Housing: An Uneasy Relationship" by Jin Xue (Routledge, 2014)......Book review of: "Economic Growth and Sustainable Housing: An Uneasy Relationship" by Jin Xue (Routledge, 2014)...

Herkommer zum Hinschauen

OpenAIRE

Schilling, Jörg

2011-01-01

Tagung: Moderne Architektur exemplarisch. Hans Herkommer (1887-1956). Technische Universität Kaiserslautern, Lehrgebiet Geschichte und Theorie der Architektur. Prof. Dr. phil. Matthias Schirren. 28.-29. Oktober 2010

Three essays on corruption and auctions

OpenAIRE

PAPIOTI, Katerina Chara

2014-01-01

Defence date: 1 December 2014 Examining Board: Professor Massimo Morelli, Bocconi University, Supervisor; Professor Andrea Mattozzi, EUI; Professor Marco Celentani, Universidad Carlos III; Professor Matthias Dahm, University of Nottingham. This thesis contributes to the understanding of corruption and auctions. It consists of three chapters focusing on diverse aspects of these two general topics as well as their combinations, from an applied microeconomic theory perspective: (i) the eff...

Mining and Analysis of SNP in Response to Salinity Stress in Upland Cotton (Gossypium hirsutum L.).

Science.gov (United States)

Wang, Xiaoge; Lu, Xuke; Wang, Junjuan; Wang, Delong; Yin, Zujun; Fan, Weili; Wang, Shuai; Ye, Wuwei

2016-01-01

Salinity stress is a major abiotic factor that affects crop output, and as a pioneer crop in saline and alkaline land, salt tolerance study of cotton is particularly important. In our experiment, four salt-tolerance varieties with different salt tolerance indexes including CRI35 (65.04%), Kanghuanwei164 (56.19%), Zhong9807 (55.20%) and CRI44 (50.50%), as well as four salt-sensitive cotton varieties including Hengmian3 (48.21%), GK50 (40.20%), Xinyan96-48 (34.90%), ZhongS9612 (24.80%) were used as the materials. These materials were divided into salt-tolerant group (ST) and salt-sensitive group (SS). Illumina Cotton SNP 70K Chip was used to detect SNP in different cotton varieties. SNPv (SNP variation of the same seedling pre- and after- salt stress) in different varieties were screened; polymorphic SNP and SNPr (SNP related to salt tolerance) were obtained. Annotation and analysis of these SNPs showed that (1) the induction efficiency of salinity stress on SNPv of cotton materials with different salt tolerance index was different, in which the induction efficiency on salt-sensitive materials was significantly higher than that on salt-tolerant materials. The induction of salt stress on SNPv was obviously biased. (2) SNPv induced by salt stress may be related to the methylation changes under salt stress. (3) SNPr may influence salt tolerance of plants by affecting the expression of salt-tolerance related genes.

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Bäcklund transformation and soliton solutions in terms of the Wronskian for the Kadomtsev–Petviashvili-based system in fluid dynamics · ZHONG DU BO TIAN ... 46 Research Article. Neutron radiation damage studies in the structural materials of a 500 MWe fast breeder reactor using DPA cross-sections from ENDF/B-VII.1.

Liposomal preparation by supercritical fluids technology | Zhong ...

African Journals Online (AJOL)

African Journal of Biotechnology ... technology (SCF) has been utilized in liposomal preparation because of its friendliness, nontoxicity to the environment and its possibility to achieve solvent-free liposomes and industrial-scale of liposome production under the conditions of current good manufacturing practice (cGMP).

The Impacts of Different PBL Schemes on the Simulation of PM2.5 during Severe Haze Episodes in the Jing-Jin-Ji Region and Its Surroundings in China

Directory of Open Access Journals (Sweden)

Tian Li

2016-01-01

Full Text Available In this study, three schemes [Yonsei University (YSU, Mellor-Yamada-Janjic (MYJ, and Bougeault-Lacarrère (Boulac] were employed in the Weather Research and Forecasting/Chemistry (WRF-Chem model to simulate the severe haze that occurred in February 2014 in the Jing-Jin-Ji region and its surroundings. The PM2.5 concentration simulated using the three schemes, together with the meteorological factors closely related to PM2.5 (wind speed, local vertical diffusivity, and PBL height, was evaluated through comparison with observations. The results indicated that the eastern plain cities produced better simulation results than the western cities, and the cities under the eastern root of Taihang Mountain produced the worst results in simulating high PM2.5 concentration in haze. All three schemes simulated very similar variation trends of the surface PM2.5 concentration compared with observations. The diurnal variations of simulated surface PM2.5 were not as reasonable as their reflection of daily averaged variation. The simulated concentrations of surface PM2.5 using the YSU, MYJ, and Boulac schemes all showed large negative errors during daytime in polluted days due to their inefficient descriptions of local atmospheric stability or diffusion processes in haze. The lower ability of PBL schemes in distinguishing the diffusion between haze and clean days in the complex topography areas in China is an important problem for PM2.5 forecasting, which is worthy of being studied in detail.

Určení hodnoty věcných břemen stavby na cizím pozemku a přechodu nebo přejezdu přes pozemek jiného vlastníka

OpenAIRE

Kuhrová, Kristýna

2011-01-01

Diplomová práce je zaměřena na problematiku věcných břemen z hlediska činnosti znalce. V první části práce je proveden rozbor platné právní úpravy věcných břemen, jejich členění, příčiny možného vzniku, změn a zániku. Dále následuje obecný popis metodiky oceňování věcných břemen, vymezení jednotlivých druhů cen a účelů oceňování věcných břemen. V návrhové části je teoretický rozbor aplikován na dva konkrétní případy věcných břemen, a to věcného břemene přechodu přes pozemek jiného vlastníka a...

Provenance and indirect dating study on Hongzhou Kiln porcelains by INAA

International Nuclear Information System (INIS)

Feng, X.Q.; Feng, S.L.; Fan, C.S.; Zhang, W.J.; Quan, K.S.

2005-01-01

Hongzhou Kiln is one of the six leading celadon kilns in Tang Dynasty and plays an important role in the history of Chinese ceramics for its diverse decoration styles and innovative technology. Archaeologists divided Hongzhou Kiln production into 8 periods, i.e. Eastern Han and Eastern Wu, Western Jin, Eastern Jin, Southern Dynasties, Sui, Early Tang, Middle Tang, Late Tang and Five Dynasties. Up to now, 26 kiln sites have been discovered and excavated. A study on the chemical composition of the porcelains of different periods and provenance will help to know the developing process of Hongzhou celadon such as variation of raw materials, recipes, manufacturing technology, causes of prosperity and decline, etc. Over 200 sherds were collected and their body samples were analyzed by INAA. The compositional differences between samples with the same period but different provenance were observed. The contents of Na, Rb, Ba, Fe, Th, U, etc were found to be different among samples from different periods, which implies they may be used to identify the manufacturing age. The analytical data were further processed by principal component analysis (PCA). The statistical results show that all the sherds can be classified into 5 groups, (1) Eastern Han and Eastern Wu; (2) Western Jin, Eastern Jin and Southern Dynasties; (3) Sui; (4) Early Tang and Middle Tang; (5) Late Tang and Five Dynasties.

Inhibition of Inducible Nitric Oxide Synthase, Cycleooxygenase-2 ...

African Journals Online (AJOL)

HP

Won Chung, Jin Uk Oh, Sehyung Lee and Sung-Jin Kim* ... was determined by Western blot analysis for iNOS and COX-2 expression in LPS-stimulated RAW ..... Nitric oxide-scavenging and antioxidant effects ofUraria crinite root. Food.

Chlorine isotopic geochemistry of salt lakes in the Qaidam Basin, China

Digital Repository Service at National Institute of Oceanography (India)

Liu, W.G.; Xiao, Y.K.; Wang, Q.Z.; Qi, H.P.; Wang, Y.H.; Zhou, Y.M.; Shirodkar, P.V.

*Cl+ ion. Int. J. Mass Spectrom. Ion Process., 116: crysatallization of saline minerals in salt lake. J. Salt Lake 183-192. Sci., 2: 35-40 (in Chinese). Xiao, Y.K., Sun, D.P., Wang, Y.H., Qi, H.P. and Jin, L., 1992. Boron isotopic compositions of brine..., sediments, and source water in Da Qaidam Lake, Qinghai, China. Geochim. Cos- mochim. Acta, 56: 1.561-1568. Xiao, Y.K., Jin, L., Liu. W.G., Qi, H.P., Wang, W.H. and Sun, D.P., 1994a. The isotopic compositions of chlorine in Da Qaidam Lake. Chin. Sci...

Why do science in space? Researchers' Night at CERN 2017

CERN Multimedia

Nellist, Clara

2017-01-01

Space topic and debate "Why do science in space?" With the special presence of Matthias Maurer, European Space Agency astronaut, and Mercedes Paniccia, PhD, Senior Research Associate for space experiment AMS.

Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin?avidin-specific binding

OpenAIRE

Liu, Yongjun; Wu, Xiaoyun; Sun, Xiaohe; Wang, Dan; Zhong, Ying; Jiang, Dandan; Wang, Tianqi; Yu, Dexin; Zhang, Na

2017-01-01

Yongjun Liu,1 Xiaoyun Wu,1 Xiaohe Sun,1 Dan Wang,1 Ying Zhong,1 Dandan Jiang,1 Tianqi Wang,1 Dexin Yu,2 Na Zhang1 1School of Pharmaceutical Science, Shandong University, 2Department of Radiology Medicine, Qilu Hospital, Jinan, People’s Republic of China Abstract: Developing magnetic resonance imaging (MRI) contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endotheli...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. Jiandong Wu1 Xiaolei Jin1 Yang Zhao1 Qing Dong1 Haiyang Jiang1 Qing Ma1. Key Laboratory of Crop Biology of Anhui Province, School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China ...

Enhancement of absorption and bioavailability of echinacoside by verapamil or clove oil

Directory of Open Access Journals (Sweden)

Shen JY

2015-08-01

Full Text Available Jin-Yang Shen,1,* Xiao-Lin Yang,2,* Zhong-Lin Yang,1 Jun-Ping Kou,1 Fei Li11State Key Laboratory of Natural Medicines, China Pharmaceutical University, 2Key Laboratory of Pharmaceutical and Biological Marine Resources Research and Development of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China*These authors contributed equally to this workPurpose: This present study investigated the absorption kinetics of echinacoside (ECH in situ and in vitro and its oral bioavailability in rats. Additional aim was to find an agent(s to promote ECH absorption and oral bioavailability among two efflux proteins and three absorption promoters.Methods: ECH absorption behaviors were investigated by everted gut sac model in vitro and single-pass intestinal perfusion model in situ. Pharmacokinetics study was performed to investigate the influences of verapamil and clove oil on ECH bioavailability in vivo. All samples were measured at different time intervals by high performance liquid chromatography.Results: The results showed that the effective permeability coefficient (Peff and apparent permeability coefficient of ECH were 0.83×10-6–3.23×10-6 cm/s and 2.99×10-6–9.86×10-6 cm/s, respectively. The Peff among duodenum, jejunum, and ileum were not statistically different, but they were higher than colon (P<0.01, which demonstrated that intestinal ECH absorption was poor and site dependent. Additionally, verapamil and clove oil significantly increased the jejunal Peff of ECH both in situ and in vitro. Moreover, the bioavailability of ECH in combination with verapamil and clove oil were increased by 1.37-fold (P<0.05 and 2.36-fold (P<0.001, respectively, when compared to ECH group. Overall, verapamil and clove oil facilitated ECH absorption and oral bioavailability.Conclusion: The absorption and bioavailability of ECH were enhanced by verapamil and clove oil, respectively, both in vitro and in vivo. Consequently

BRAIN JOURNAL - PREFACE (OF THE FIRST SPECIAL ISSUE)

OpenAIRE

Bogdan Patrut

2010-01-01

BRAIN. Broad Research in Artificial Intelligence and Neuroscience, ISSN 2067-3957, Volume 1, July 2010, Special Issue on Complexity in Sciences and Artificial Intelligence Editors • Barna Iantovics, Petru Maior University, Targu Mures, Romania • Dumitru Rădoiu, Petru Maior University, Targu Mures, Romania • Marius Măruşteri, Universiy of Medicine and Pharmacy, Targu Mures, Romania • Matthias Dehmer, Institute for Bioinformatics and Translational Research, The Health and Life Scien...

Quantification of human errors in level-1 PSA studies in NUPEC/JINS

International Nuclear Information System (INIS)

Hirano, M.; Hirose, M.; Sugawara, M.; Hashiba, T.

1991-01-01

THERP (Technique for Human Error Rate Prediction) method is mainly adopted to evaluate the pre-accident and post-accident human error rates. Performance shaping factors are derived by taking Japanese operational practice into account. Several examples of human error rates with calculational procedures are presented. The important human interventions of typical Japanese NPPs are also presented. (orig./HP)

[Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung. Livland, Estland, Ösel, Ingermanland, Kurland und Letgallen. Stadt, Land und Konfession 1500-1721. 2. und 3. Teil] / Anti Selart

Index Scriptorium Estoniae

Selart, Anti, 1973-

2012-01-01

Arvustus: Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung. Livland, Estland, Ösel, Ingermanland, Kurland und Letgallen. Stadt, Land und Konfession 1500-1721. Hrsg. von Matthias Asche, Werner Buchholz, Anton Schindling. 2. und 3. Teil.

Total Gastric Necrosis: A Case Report and Literature Review

African Journals Online (AJOL)

2017-05-22

123 beats/min) with atrial fibrillation, and suspicious abdominal tenderness with positive shifting dullness. B-ultrasonography of the abdomen showed peritoneal ascites, and diagnostic abdominal paracentesis. G Huang, Y Jin1.

High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis

OpenAIRE

Yuan, Zhong-Yu; Luo, Rong-Zhen; Peng, Rou-Jun; Wang, Shu-Sen; Xue, Cong

2014-01-01

Zhong-Yu Yuan,1–3* Rong-Zhen Luo,1,2,4,* Rou-Jun Peng,1–3 Shu-Sen Wang,1–3 Cong Xue1–3 1State Key Laboratory of Oncology in South China, 2Collaborative Innovation Center for Cancer Medicine, 3Departments of Medical Oncology, Sun Yat-Sen University Cancer Center, 4Departments of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, People’s Republic of China  *These authors contributed equally to this work Background: Triple-ne...

Mari Rahumägi kui särav piksevarras / Katri Soe

Index Scriptorium Estoniae

Soe, Katri

2006-01-01

Euroopa suurima postimüügi kontserni Karstadt-Quelle Eesti tütarfirma tegevjuhi karjäärist, oma äri alustamisest ja siirdumisest palgatööle. Kommenteerivad Jaanus Rahumägi, Helina Tuuna, Matthias Fink

57. Baltisches Historikertreffen : vom 5. bis 6. Juni 2004 in Göttingen

Index Scriptorium Estoniae

2004-01-01

57. balti ajaloolaste kohtumisel 5.-6. juunini 2004 esinesid ettekannetega Erki Tammiksaar, Tiit Rosenberg, Olaf Mertelsmann, Klaus Neitmann, Matthias Thumsen, Ilgvars Misans, Henrik Bolte, Thomas Brück, Juhan Kreem, Dieter Heckmann, Stefan Hartmann. Ettekannete kokkuvõtted

Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate

OpenAIRE

Li, Feng; Chen, Yan; Liu, Shubo; Qi, Jian; Wang, Weiying; Wang, Chenhua; Zhong, Ruiyue; Chen, Zhijun; Li, Xiaoming; Guan, Yuanzhou; Kong, Wei; Zhang, Yong

2017-01-01

Feng Li,1 Yan Chen,1,2 Shubo Liu,1 Jian Qi,1 Weiying Wang,1 Chenhua Wang,1 Ruiyue Zhong,1 Zhijun Chen,1 Xiaoming Li,1 Yuanzhou Guan,1 Wei Kong,1,2 Yong Zhang1,2 1National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 2Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China Abstract: Zein-based nano/microparticles have been demonstrated to be promising carr...

RETRACTED: Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population.

Science.gov (United States)

Zhou, Tian-Biao; Guo, Xue-Feng; Jiang, Zongpei; Li, Hong-Yan

2015-12-01

The following article has been included in a multiple retraction: Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January

Toxicity evaluation of biodegradable chitosan nanoparticles using a zebrafish embryo model

OpenAIRE

Hu YL; Qi W; Han F; Shao JZ; Gao JQ

2011-01-01

Yu-Lan Hu1, Wang Qi1, Feng Han2, Jian-Zhong Shao3, Jian-Qing Gao11Institute of Pharmaceutics, College of Pharmaceutical Sciences, 2Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, 3College of Life Sciences, Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaBackground: Although there are a number of reports regarding the toxicity evaluation of inorganic nanoparticles, knowledge on bi...

Symposium in honour of Ugo Amaldi's 60th birthday

CERN Document Server

Myatt, Gerald; Ellis, Jonathan Richard; Kalmus, George Ernest; Llewellyn Smith, Christopher Hubert; Matthiae, Giorgio; Richter, Burton; Wiik, Bjørn Haavard; Winter, Klaus; CERN. Geneva

1994-12-07

Ugo Amaldi,a man of science , G Myattpp total cross section, G Matthiae Neutrino physics, K Winter DELPHI & LEP physics, G Kalmus Supersymmetry, J EllisElectron-proton physics, B WiikLinear colliders, B Richter Closing address, C Llewellyn Smith -

[Walter Matthias Diggelmann--the healing effect of story telling].

Science.gov (United States)

Schmid, H J

2001-06-21

"Stories are weapons against disease" wrote Swiss writer WM Diggelmann (1927-1979). In writing stories he hoped to counteract the lethal course of his cancer. In the past it had helped him to overcome destitution and social disgrace and had given him identity. His last story Walking on the Island of St. Margaret is a ritual which conjures up an intact future by celebrating the past. Stories try to explain the world. They inform or clarify emotions. In telling stories, doctors and nurses demonstrate sympathy and understanding. Perhaps even greater benefits might be derived from patients telling their own stories. In doing so they emerge as individuals and give their lives purpose. Language is more than communication: it is shelter, link, home, ritual. Storytelling helps patients cope with their diseases. It is not clear whether this or any technique of psychotherapy has any effect upon the course of cancer.

The Militia of Jin-Cha-Ji Border Area in the Anti-Japanese War Period%抗战时期晋察冀边区的民兵

Institute of Scientific and Technical Information of China (English)

栾盈菊

2013-01-01

晋察冀民兵是在共产党的动员和领导下建立和壮大起来的不脱离生产的群众武装。民兵的任务是进行游击战、配合部队作战和担任抗战勤务。民兵的军事战术有麻雀战、地雷战、地道战、扭击战和伏击战等。在民兵队伍中，由于有党的政治动员、党员的带头作用、有组织的军事政治教育和组织的民主性等原因，民兵成为打败日寇的重要力量，同时民兵也是主力军与游击队的助手，是主力军的重要兵源。%The militia of Jin-Cha-Ji border area was the armed masses without departing from the pro-duction,which was established and grew under the leadership of the Party.Its mission was to carry outguerrilla warfare,cooperate with the troops and act as war service.It had many tactics,such as sparrowwarfare,mine warfare,tunnel warfare,torsional warfare and ambush operation.Due to the Party’s politi-cal mobilization and the Party members’leading role,with organized military and political education anddemocratic nature of the organization,the militia was not only an important force to beat the Japanese,butalso assistant of the main force and the guerrillas,and the important sources for the recruits of the mainforce troops.

Fermentation characteristics of Korean pear (Pyrus pyrifolia Nakai ...

African Journals Online (AJOL)

USER

2010-08-30

Aug 30, 2010 ... Dong Chung Kim1, Hee Jeong Chae2,3 and Man-Jin In1*. 1Department of Human ... 0.3% proteins and 0.2% lipids (Hwang and Park, 2006). It is primarily consumed as ..... Khan SH, Ansari FA (2007). Probiotics – the friendly ...

China's 'recycling economy'

DEFF Research Database (Denmark)

Mehlsen, Camilla

2009-01-01

Climate change and sustainability are hot topics in China, but it is hard to find research addressing the outcomes of Education for Sustainable Development, says Associate Professor Yi Jin.......Climate change and sustainability are hot topics in China, but it is hard to find research addressing the outcomes of Education for Sustainable Development, says Associate Professor Yi Jin....

Video Histories, Memories, and Coincidences

DEFF Research Database (Denmark)

Kacunko, Slavko

2012-01-01

Looping images allows us to notice things that we have never noticed before. Looping a small but exquisite selection of the video tapes of Marcel Odenbach, Dieter Kiessling and Matthias Neuenhofer may allow the discovering of Histories, Coincidences, and Infinitesimal Aesthetics inscribed...

Igatsedes mägesid

Index Scriptorium Estoniae

2008-01-01

Näitus "Igatsedes mägesid. Šveitsi maastikud Balti kunstis" Kadrioru Kunstimuuseumis. Vaadeldakse Balti kunstnike joonistusreise Šveitsi 18. sajandi teisel poolel ja 19. sajandi alguses. August Matthias Hageni (1794-1878), Carl Grassi (1767-1814), Wilhelm Krause (1757-1728) elust ja loomingust

Comparative immunomudulating effects of five orally administrated ...

African Journals Online (AJOL)

plzfg

inflammatory cytokine ..... expression and induction of manganese-superoxide dismutase in the adenohypophysis. Histochem. ... Sugino N, Hirosawa-Takamori M, Zhong L, Telleria CM, Shiota K & Gibori G (1998) Hormonal regulation of.

Quantitative trait locus (QTL) mapping for 100-kernel weight of ...

African Journals Online (AJOL)

hope&shola

2010-12-06

Dec 6, 2010 ... regimes. Xiao-Hong Liu1, Zu-Ping Zheng2*, Zhen-Bo Tan3, Zhong Li2 and Chuan He2 ... al., 2005; Liu et al., 2007; Wang et al., 2007a; Guo et al.,. 2008; Tang .... They could individually account for 12.63, 7.22, 4.47 and 14.47% of .... Liu ZH, Tang JH, Wei XY, Wang EL, Tian GW, Hu YM, Chen WC. (2007).

Nový zákon tzv. Svatováclavské bible (1677)

Czech Academy of Sciences Publication Activity Database

Koupil, Ondřej

2013-01-01

Roč. 5, č. 2 (2013), s. 95-106 ISSN 1804-1132 R&D Projects: GA MK(CZ) DF12P01OVV028 Keywords : Bible in Czech * New Testament 1677 * Georgius Constantius SI * Matthias Steyer SI * Cornelius a Lapide SI Subject RIV: AI - Linguistics

Long-Time Dynamics of Open Quantum Systems

DEFF Research Database (Denmark)

Westrich, Matthias

Matthias Westrich studied the effective evolution of atoms coupled to quantised fields and determined the rate at which atoms relax to their ground state. For positive temperature, he also characterised properties of (quasi-)stationary states for atoms in contact with a heat bath and driven...

List of Registered Participants

Indian Academy of Sciences (India)

user1

Heald, George. ASTRON heald@astron.nl. Hoeft, Matthias. Thueringer Landessternwarte Tautenburg hoeft@tls-tautenburg.de. Ishwara Chandra, C. H.. NCRA-TIFR ishwar@ncra.tifr.res.in. Johnston-Hollitt, Melanie. School of Chemical & Physical Sciences. Melanie.Johnston-Hollitt@vuw.ac.nz. Jacob, Joe. Newman College.

Diagnostic utility of clinical and biochemical parameters in ...

African Journals Online (AJOL)

Diagnostic utility of clinical and biochemical parameters in pancreatic head malignancy patients with normal carbohydrate antigen 19-9 levels. Xiaoli Jin1, Yulian Wu2. 1. Department of Surgery, Sir Run Run Shaw Hospital College of Medicine, Zhejiang University, 3 Qingchun. Road East, Hangzhou, Zhejiang Province ...

Biisofraxidin on Apoptosis of Human Gastric Cancer BGC-823 Cells

African Journals Online (AJOL)

Wu et al. Trop J Pharm Res, October 2015; 14(10): 1803. Tropical Journal of Pharmaceutical Research ... Jian-Tao Wu1,2*, She-Min Lv1, Chun-Hui Lu1, Jun Gong1 and Jian-Bo An3 ..... Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB,.

Alterations of the Bone Marrow Microenvironment Contribute to Prostate Cancer Skeletal Metastasis

Science.gov (United States)

2012-05-01

clinical S. I. Park : F. N. Soki : L. K. McCauley (*) Department of Periodontics and Oral Medicine, The University of Michigan School of Dentistry, 1011 N... chronic angiogenesis. Am J Pathol 174(5):1972–1980. doi:10.2353/ ajpath.2009.080819 90. Shojaei F, Zhong C, Wu X, Yu L, Ferrara N (2008) Role of...anoikis in prostate cancer cells Serk In Park1 and Laurie K McCauley1,2 1Department of Periodontics and Oral Medicine, University of Michigan School of

Provenance and indirect dating study on Hongzhou Kiln porcelains by INAA

International Nuclear Information System (INIS)

Feng, X.Q.; Feng, S.L.; Quan, K.S.

2007-01-01

Over 100 sherds were collected from Hongzhou Kiln of Jiangxi Province, China and their body samples were analyzed by INAA. The compositional differences between samples with the same period but different provenance were observed. The contents of Na, Rb, Ba, Fe, Th, U, etc., were found to be different among samples from different periods, which implies they may be used to identify the manufacturing age indirectly. The analytical data were further processed by principal components analysis (PCA). The statistical results show that all the sherds can be classified into 5 groups: (1) Eastern Han and Eastern Wu; (2) Western Jin, Eastern Jin and Southern Dynasties; (3) Sui; (4) Early Tang and Middle Tang; (5) Late Tang and Five Dynasties. (author)

HYPERSONIC BOUNDARY LAYER TRANSITION EXPERIMENTS- HYPERSONIC INTERNATIONAL FLIGHT RESEARCH EXPERIMENTATION 5 (HIFIRE-5) AND CIRCULAR CONE

Science.gov (United States)

2016-10-01

mode.53, 73 , 74 An example of narrow-band response (NBR) is indicated in Figure 4-11, as well as an example of broad-band response (BBR). The narrow...dimensionless a = width of unobstructed light source b = width of light-source image A1 = disturbance amplitude at lower neutral bound, dimensionless Cp ...of Laminar Flow, edited by R. Michel, AGARD Report No. 709, pp. 3-1 to 3-81, 1984. 54 Lei, J. and Zhong, X., “Linear Stability Analysis of Nose

Joint Institute for Nanoscience Annual Report 2003

Energy Technology Data Exchange (ETDEWEB)

Baer, Donald R.; Campbell, Charles

2004-02-01

The Joint Institute for Nanoscience (JIN) is a cooperative venture of the University of Washington and Pacific Northwest National Laboratory to encourage and enhance high-impact and high-quality nanoscience and nanotechnology of all types. This first annual report for the JIN summarizes activities beginning in 2001 and ending at the close of fiscal year 2003 and therefore represents somewhat less than two years of activities. Major portions of the JIN resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by Pacific Northwest National Laboratory (PNNL) staff scientists and University of Washington (UW) professors. These fellowships were awarded on the basis of applications that included research proposals. JIN co-sponsors an annual Nanoscale Science and Technology Workshop held in Seattle. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the University of Alaska. The initial JIN agreement recognized that expansion of cooperation beyond UW and PNNL would be highly valuable. Starting in early 2003, efforts were initiated to form a regional communication link called the Northwest Nanoscience and Nanotechnology Network (N₄). In concept, N₄ is a tool to encourage communication and help identify regional resources and nanoscience and technology activities.

Novel circulatory connection from the acupoint Zhong Wan(CV12 to pancreas

Directory of Open Access Journals (Sweden)

Minsoo Kim

2008-03-01

Full Text Available Objectives : Demonstrating a novel circulatory path from the acupoint(CV12 to the pancreas. Method : Alcian blue(1% solution, 20μl, pH 7.4 was injected into the acupoint(CV12. Two hours later the surfaces of internal organs were observed by using a stereomicroscope. Results : Alcian blue arrived and colored the omental fat band(OFB on the pancreas. The OFB connected the head and tail of the pancreas, the pancreas and the spleen, and the pancreas and the stomach. Conclusion : The existence of a novel circulatory path from the acupoint CV12 to the pancreas and its OFB was demonstrated.

25 October 2017- Austrian, German and Swiss Science Foundations signing the guest book in the Globe of Science and Innovation

CERN Multimedia

Ordan, Julien Marius

2017-01-01

Austrian, German and Swiss Science Foundations in Globe: Professor Klement Tockner, Präsident, Fonds zur Förderung der wissenschaftlichen Forschung, Austria; Professor Peter, Strohschneider, Präsident, Deutsche Forschungsgemeinschaft Germany; Professor Matthias Egger, Präsident, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Switzerland

Environmental law. 2. rev. and enl. ed.; Umweltrecht

Energy Technology Data Exchange (ETDEWEB)

Koch, H.J. (ed.) [Hamburg Univ. (Germany). Forschungsstelle Umweltrecht

2007-07-01

The text book under consideration already is addressed to lawyers and students of jurisprudence. It enables an introduction into the general environmental law and consists of sixteen autonomous chapters: (a) International law in the field of ecology (Matthias Buck, Roda Verheyen); (b) European and national environmental constitutional law (Johannes Caspar); (c) General environmental administrative law (Ulrich Ramsauer); (d) Pollution abatement law (Hans-Joachim Koch); (e) Water protection law (Silke Laskowski, Cornelia Ziehm); (f) Recycling economy law and waste management law (Martin Dieckmann, Moritz Reese); (g) Nature conservation law (Christian Maass, Peter Schuette); (h) Soil conservation law and contaminated sites law (Nikolaus Herrmann); (i) Energy legal regulations as an instrument of environmental protection (Wolfgang Ewer); (j) Atomic energy law (Klaus Jankowski); (k) Genetic engineering law (Ursula Prall); (l) Law of hazardous materials (Eckhard Pache); (m) Environmental law in planning law (Nikolaus Hermann); (n) Environment and traffic (Philipp Hermann, Ekkehard Hofmann); (o) Agriculture and ecology (Ulf-Henning Moeker); (p) Liberal trade and environmental protection (Matthias Buck).

Research Article Special Issue

African Journals Online (AJOL)

2017-09-10

Sep 10, 2017 ... include revolvers, self-loading pistols, rifles, carbines, assault rifles, submachine .... This section provides related theory on spring that was modelled in the .... Zhong-Xian L. Development and experimental verification of a.

Studies on middle silkgland proteins of cocoon colour sex-limited ...

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 29; Issue 1. Studies on middle silkgland proteins of cocoon colour sex-limited silkworm (Bombyx mori L.) using two-dimensional polyacrylamide gel electrophoresis. Yuan-Xiang Jin Yu-Yin Chen Meng-Kui Xu Yong-Huang Jiang. Articles Volume 29 Issue 1 March 2004 pp 45- ...

Effects of carbon ion irradiation on survival rate, catalase and peroxidase activity of alfalfa M1 under low temperature stress

International Nuclear Information System (INIS)

Wang Shuyang; Li Jinghua; Jiang Boling

2014-01-01

In this study, three kinds of alfalfa including Zhonglan 1, BC-04-477 and Ta Cheng were treated with different doses of "1"2C"6"+ (75 keV) heavy ion radiation, and then the influence of survival rate, catalase (CAT) and peroxidase (POD) activity of M1 with low temperature stress were tested. The results showed that under the condition of 400 Gy radiation dose, the survival rate and CAT activity of Zhonglan 1 under low temperature stress have increased by 33.3%, 56.3% respectively compared with those of the control group, while there was no difference in POD activity between those two groups. The survival rate, CAT and POD activity of BC-04-477 treated with low temperature have been improved by 33.3%, 69.2%, 5.1% respectively compared with those of the control group when the radiation dose was 400 Gy. Compared with those of the control group, the survival rate, CAT and POD activity of Ta Cheng under low temperature stress have been improved by 25%, 26%,22.8% respectively when the radiation dose was 800 Gy. These results indicate that the viability and the cold resistance ability of Zhong Lan 1, BC-04-477 and Ta Cheng can be improved by "1"2C"6"+ radiation. (authors)

77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Science.gov (United States)

2012-11-01

... BOUCHARD RAYMOND JOSEPH BOULLE II JEAN-RAYMOND BROMLEY MARGARET ANNE BROWNE CARLA EVELYN BRUCE JAMES TODD... CAMINOS MICHELE CLARE CAMPBELL JESSICA ANNE CHANG WAYNE WEN TIEN CHAN-PALAY VICTORIA LYE-HUA CHEN HOPE MI... RICHARD JOSEPH ARTHUR FUKUDA MEGUMI GAEHWILER YANNIK PETER GEIGER DANIEL CHRISTIAN GEIGER MICHAEL MATTHIAS...

More and more together : Legal family formats for same-sex and different-sex couples in European countries – Comparative analysis of data in the LawsAndFamilies Database

NARCIS (Netherlands)

Waaldijk, C.

2017-01-01

This report (edited by Kees Waaldijk) includes contributions by Daniel Damonzé, Marie Digoix, Marina Franchi, Natalie Nikolina, José Ignacio Pichardo Galán, Giulia Selmi, Matias de Stéfano Barbero, Matthias Thibeaud, Jose A.M. Vela, Kees Waaldijk, and Giuseppe Zago. This report offers a

African Journal of Biotechnology - Vol 11, No 70 (2012)

African Journals Online (AJOL)

Embryogenesis and plant regeneration from unpollinated ovaries of Amorphophallus konjac · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Lingling Zhao, Jinping Wu, Ying Diao, Zhongli Hu, 13472-13476 ...

A kinetic model for citric acid productionfrom apple pomac by ...

African Journals Online (AJOL)

STORAGESEVER

2008-10-06

Oct 6, 2008 ... system. The model can provide useful suggestions for the analysis, design and operation of a fermenter. Fer- mentation models are normally ... Structured model seems complicated for normal use. (Jian-Zhong et al., 2002).

The Effect of Caffeine on Human Dark Adaptation.

Science.gov (United States)

1977-04-06

UO~ mg. 100 mg .< Placebo T.M. 13** 9 3** G..11 (2 te)10 S.H. 9 (1 tie) 4 13** P < .05 **p. .005 N =13 K 9 EXPERIMENT II The analysis of Experiment...caffeinated session were not included in the analysis . A double blind design was again employed. Each S received a schedule in accordance wihh which he... tannins , and sodium in coffee, tea and cocoa. Journal of the American Medical Association, 1955, 158, 1030-1031. 17. Matthias, H., 8 Erdmann, D. The

Kinesthetic Ventures Informed by the Work of F. M. Alexander, Stanislavski, Peirce, and Freud.

Science.gov (United States)

Bouchard, Ed; Wright, Ben; Protzel, Michael, Ed.

This book is about education harvested from self-observation. F. Matthias Alexander (1869-1955) studied the experience of self formation, working with motor habits. His method is used in performing arts training to enhance bodily and vocal expression. Like Alexander, Konstantine Stanislavski (1863-1938) and Sigmund Freud (1856-1939) studied human…

Teekonnad tajutunnelites / Aita Kivi

Index Scriptorium Estoniae

Kivi, Aita, 1954-

2001-01-01

Sisu : Siri Hustvedt. Pimesi; Boris Vian. Päevade vaht; Christian Lore Weber. Altarimuusika; Kurt Vonnegut. Kassikangas; Jean Sasson. Printsess Sultana tütred; Karen Robards. Senaatori naine; Matthias Johann Eisen. Näkid, kratid, luupainajad; Mats Traat. Harala elulood; Steven L. McKenzie. Kuningas Taavet; Sally Ward. Terane laps; Ted Hughes. Luuletused

Kindla peale minek / Küllo Arjakas

Index Scriptorium Estoniae

Arjakas, Küllo, 1959-

2007-01-01

Rets. rmt.: Eberle, Henrik ; Ulm, Matthias. Hitleri toimik : NKVD salajane ettekanne Jossif Stalinile, koostatud Hitleri isikliku adjutandi Otto Günsche ja kammerteener Heinz Linge ülekuulamise protokollide põhjal Moskvas 1948/49. [Tallinn] : Tammerraamat, 2006 ; Bassett, Richard. Canaris : Hitleri luureülem : Wilhelm Canarise mõistatus : [1887-1945]. Tallinn : Varrak, 2006

Remote Sensing of Selected Water-Quality Indicators with the Hyperspectral Imager for the Coastal Ocean (HICO) Sensor

Science.gov (United States)

2014-01-01

the bands needed for atmospheric correction. Spectral definition files for AVIRIS, HYDICE, HYMAP, HYPERION, CASI, and AISA sensors are included as...Satellite Visible Imagery – A Review.” In Lecture Notes on Coastal and Estuarine Studies, edited by R. T. Barber, N. K. Mooers, M. J. Bowman, and B...In Proceedings of SPIE Coastal Ocean Remote Sensing, edited by Robert J. Frouin, ZhongPing Lee, Vol. 6680, 668013-1-668013-9. doi:10.1117/12.736845

A Novel Extraction Approach of Extrinsic and Intrinsic Parameters of InGaAs/GaN pHEMTs

Science.gov (United States)

2015-07-01

A Novel Extraction Approach of Extrinsic and Intrinsic Parameters of InGaAs/GaN pHEMTs Andong Huang1, 2, ZhengZhong2, 3, and Yongxin Guo2, 3...Suzhou Research Institute, Suzhou, China Abstract — A novel extraction approach of extrinsic and intrinsic parameters of InGaAs/GaN pHEMTs is...parameter error function. The extrinsic elements are optimized at multi-bias points and the intrinsic ones at specific bias points. Only broad ranges

ESTUDIO COMPARATIVO DEL EFECTO DE ZHONGJI (RM3) MOXADO MAS PUNTOS REGULARES VS PUNTOS REGULARES EN PACIENTES CON NEUROPATIA DIABETICA -NO TIENE CARATULA-

OpenAIRE

LERMA GARCIA, HECTOR ALFONSO

2010-01-01

ANTECEDENTES: DESDE LA ANTIGUEDAD SE HA COMPROBADO LA EFECTIVIDAD DE LA ACUPUNTURA PARA EL TRATAMIENTO DEL DOLOR Y PARA LA DIABETES EN EL SER HUMANO. OBJETIVO: EL PRESENTE ESTUDIO TIENE COMO OBJETIVO ANALIZAR EL EFECTO DEL TRATAMIENTO DEL DOLOR Y ALTERACIONES SENSITIVAS EN PACIENTES CON NEUROPATIA DIABETICA. METODO: SE ESTUDIARON TREINTA PACIENTES CON UN DIAGNOSTICO DE NEUROPATIA DIABETICA LOS CUALES SE DIVIDIERON EN TRES GRUPOS A LOS CUALES SE LES APLICO EN EL GRUPO 1 ZHONG...

Matouš Konečný a jeho podíl na výchově a vzdělávání bratrských duchovních na počátku 17. století

Czech Academy of Sciences Publication Activity Database

Just, Jiří

-, č. 18 (2016), s. 75-88 ISSN 1802-2502 R&D Projects: GA ČR GA13-08740S Institutional support: RVO:67985955 Keywords : Matouš Konečný * education of clergy * protestant ecclesiastical administration * Matthias Martini * gymnasium illustre in Bremen * peregrinatio academica * protestant schoolbooks * Bohemian Brethren Subject RIV: AB - History

Formal modeling and verification of systems with self-x properties

OpenAIRE

Reif, Wolfgang

2006-01-01

Formal modeling and verification of systems with self-x properties / Matthias Güdemann, Frank Ortmeier and Wolfgang Reif. - In: Autonomic and trusted computing : third international conference, ATC 2006, Wuhan, China, September 3-6, 2006 ; proceedings / Laurence T. Yang ... (eds.). - Berlin [u.a.] : Springer, 2006. - S. 38-47. - (Lecture notes in computer science ; 4158)

SHORT COMMUNICATION DETERMINATION OF CYPERMETHRIN ...

African Journals Online (AJOL)

Preferred Customer

Spectra-physics SP8810 HPLC, equipped with UV detector; N-1NW revolving evaporator (Tokyo Physics and Chemistry Company, Japan); high-speed homogenizer (German. IKA Company); HY-4 timing multi-oscillator (JiangSu JinSheng Apparatus Factory); T500 electronic balance (ChangShu Testing Apparatus Factory); ...

Characterization of silver nanoparticles prepared by wet chemical ...

African Journals Online (AJOL)

Results: The silver nanoparticles formed were spherical in shape with mean size of 10.3 nm. The ... antibacterial activity against various strains of bacteria. Keywords: Wet ..... Fang J, Zhong C, Mu R. The study of deposited silver particulate ...

Expert consensus on acute exacerbation of chronic obstructive pulmonary disease in the People's Republic of China

Directory of Open Access Journals (Sweden)

Cai BQ

2014-04-01

Full Text Available Bai-qiang Cai,1 Shao-xi Cai,2 Rong-chang Chen,3 Li-ying Cui,4 Yu-lin Feng,5 Yu-tong Gu,6 Shao-guang Huang,7 Rong-yu Liu,8 Guang-nan Liu,9 Huan-zhong Shi,10 Yi Shi,11 Yuan-lin Song,6 Tie-ying Sun,12 Chang-zheng Wang,13 Jing-lan Wang,1 Fu-qiang Wen,5 Wei Xiao,14 Yong-jian Xu,15 Xi-xin Yan,16 Wan-zhen Yao,17 Qin Yu,18 Jing Zhang,6 Jin-ping Zheng,3 Jie Liu,6 Chun-xue Bai6 1Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 2Southern Medical University South Hospital, Guangzhou, 3The First Affiliated Hospital of Guangzhou Medical College and Guangzhou Institute of Respiratory Diseases, Guangzhou, 4Affiliate Hospital of Inner Mongolia Medical University, Huhehaote, 5Huaxi Hospital of Sichuan University, Chendu, 6Zhongshan Hospital, Shanghai Medical College, Fudan University and Shanghai Respiratory Research Institute, Shanghai, 7Ruijing Hospital of Shanghai Jiaotong University, Shanghai, 8The First Affiliated University of Anhui Medical University, Hefei, 9The First Affiliated University of Guangxi Medical University, Nanning, 10Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 11General Hospital of Nanjing Military Region, Nanjing, 12Beijing Hospital of the Ministry of Health, Beijing, 13Xinqiao Hospital, Third Military Medical University, Chongqing, 14Qilu Hospital of Shandong University, Jinan, 15Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 16The Second Affiliated Hospital of Hebei Medical University and Hebei Research Institute of Respiratory Medicine, Shijiazhuang, 17The Third Affiliated Hospital of Beijing University, Beijing, 18The First Affiliated University of Lanzhou University, Lanzhou, People's Republic of China Abstract: Chronic obstructive pulmonary disease (COPD is a common disease that severely threatens human health. Acute exacerbation of COPD (AECOPD is a major cause of

Peeter I residentsid / Jüri Kuuskemaa

Index Scriptorium Estoniae

Kuuskemaa, Jüri, 1942-

2005-01-01

Peeter I linnaresidents Tolli t. 4 Tallinnas, maja (1662, 1714) ning lossi- ja pargiansambel (1718, arhitekt Niccolo Michetti, 1923. aasta sügisest ehitusel vastutav Mihhail Zemtsov, stukk Antonio Quadri, Salomon Zeltrecht, Matthias Seidtinger, Heinrich von Bergen, laemaal "Diana ja Aktaion" - Ernst Wilhelm Londicer noorem?, laemaaling merepoolses tiibhoones - Johann Heinrich Fick) Kadriorus. Bibliograafia lk. 454

induced by NF-κB Decoy method

African Journals Online (AJOL)

control of immunity. Nature. 1998; 392(6673):245-252. Kabalak G, Dobberstein SB, Matthias T, Reuter S,. 5. The YH, Dorner T, Schmidt RE, Witte T. Association of immunoglobulin-like transcript 6 deficiency with. Sjogren's syndrome. Arthritis Rheum. 2009; 60(10):2923-. 2925. Bonham CA, Peng L, Liang X, Chen Z, Wang L, ...

Kunstitudengid näitavad Maarjamäe lossi pargis oma vabadussamba tõlgendusi

Index Scriptorium Estoniae

2008-01-01

Eesti Kunstiakadeemia skulptuuritudengid Marit Mardla, Matthias-Jakob Sildnik, Mikk Madisson, Liis Dvorjanski, Uku Sepisvart, Hannes Aasamets, Kadri Allekand, Kristin Orav, Loore Raav, Jekaterina Kultajeva, Li Yang, Kristel Aasjõe, Liivi Tantaal, Jass Kaselaan, Edith Karlson, Kadri Metstak, Berit Talpsepp ja Eike Eplik näitavad oma töid näitusel "Vabaduse monumendid"

mica – music information center austria

OpenAIRE

2010-01-01

1994 wurde das österreichische Musikinformationszentrum (mica) im Auftrag des österreichischen Bundesministers für Unterricht und Kunst (Rudolf Scholten) von den Bundeskuratoren für Musik (L. Knessl, Christian Scheib) gegründet (Geschäftsführer 1994–99 Matthias Finkentey, 1999–09 Peter Rantasa, ab 2009 Sabine Reiter).

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Soo-Dong Woo1 Jae Young Choi2 Yeon Ho Je2 Byung Rae Jin3. Department of Plant Medicine, College of Agriculture, Life and Environment Sciences, Chungbuk National University, Cheongju 361-763, Korea; School of Agricultural Biotechnology, College of Agriculture and Life Sciences, Seoul National University, Seoul ...

Modelling the response of shallow groundwater levels to combined climate and water-diversion scenarios in Beijing-Tianjin-Hebei Plain, China

Science.gov (United States)

Li, Xue; Ye, Si-Yuan; Wei, Ai-Hua; Zhou, Peng-Peng; Wang, Li-Heng

2017-09-01

A three-dimensional groundwater flow model was implemented to quantify the temporal variation of shallow groundwater levels in response to combined climate and water-diversion scenarios over the next 40 years (2011-2050) in Beijing-Tianjin-Hebei (Jing-Jin-Ji) Plain, China. Groundwater plays a key role in the water supply, but the Jing-Jin-Ji Plain is facing a water crisis. Groundwater levels have declined continuously over the last five decades (1961-2010) due to extensive pumping and climate change, which has resulted in decreased recharge. The implementation of the South-to-North Water Diversion Project (SNWDP) will provide an opportunity to restore the groundwater resources. The response of groundwater levels to combined climate and water-diversion scenarios has been quantified using a groundwater flow model. The impacts of climate change were based on the World Climate Research Programme's (WCRP's) Coupled Model Intercomparison Project phase 3 (CMIP3) multi-model dataset for future high (A2), medium (A1B), and low (B1) greenhouse gas scenarios; precipitation data from CMIP3 were applied in the model. The results show that climate change will slow the rate of decrease of the shallow groundwater levels under three climate-change scenarios over the next 40 years compared to the baseline scenario; however, the shallow groundwater levels will rise significantly (maximum of 6.71 m) when considering scenarios that combine climate change and restrictions on groundwater exploitation. Restrictions on groundwater exploitation for water resource management are imperative to control the decline of levels in the Jing-Jin-Ji area.

Embryogenesis and plant regeneration from unpollinated ovaries of ...

African Journals Online (AJOL)

Embryogenesis and plant regeneration from unpollinated ovaries of Amorphophallus konjac. Lingling Zhao, Jinping Wu, Ying Diao, Zhongli Hu. Abstract. The system of somatic embryogenesis of Amorphophallus konjac had been built through unpollinated ovaries. The embryogenic calli were induced on Murashige and ...

QTL mapping for combining ability in different population-based ...

Indian Academy of Sciences (India)

based NCII designs: a simulation study. Lanzhi Li, Congwei Sun, Yuan Chen, Zhijun Dai, Zhen Qu, Xingfei Zheng, Sibin Yu,. Tongmin Mou, Chenwu Xu and Zhongli Hu. J. Genet. 92, 529–543. Journal of Genetics, Vol. 92, No. 3, December 2013 ...

Author Details

African Journals Online (AJOL)

Zhong, Jianghua. Vol 21, No 2 (2007) - Articles APPLICATION OF ο-TOLIDINE AS SUBSTRATE FOR THE ELECTROCHEMICAL DETERMINATION OF HEMOGLOBIN OR HYDROGEN PEROXIDE Abstract PDF. ISSN: 1726-801X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

突发群体事件后乌鲁木齐市中湾街沿街居民精神障碍流行病学调查%Epidemiological survey of mental disorder along the Zhong-wan street in the Urumqi after the emergency of group injury

Institute of Scientific and Technical Information of China (English)

徐向东; 吕淑云; 夏叶玲; 贾丽娜; 胡新伟; 买买提热夏提·吐尔逊; 张莉; 李月娥; 陈亮

2014-01-01

目的 了解乌鲁木齐市突发群体事件后中湾街沿街年龄≥15岁居民各类精神障碍的患病率、发病因素及规律,为街道社区心理卫生服务尤其是心理危机干预提供依据.方法 2009年9月5日至11月5日对乌鲁木齐市黑甲山后街社区沿街居民进行了调查,对其中中湾街沿街年龄≥15岁全体居民,由精神科医生以DSM-Ⅳ-TR轴Ⅰ障碍临床定式检查患者版进行了调查,使用DSM-Ⅳ对各类精神障碍进行诊断.结果 (1)共有931人完成了调查,精神障碍的总时点患病率为24.3％(226/931),最常见的精神障碍为创伤后应激障碍(post traumatic stress disorder,PTSD)(13.5％,126/931),重性抑郁障碍(8.7％,81/931)和未特定抑郁障碍(3.4％,32/931).(2)高暴露组总患病率为41.3％(143/346),高于低暴露组(14.2％,83/585),差异有统计学意义(P＜0.01);年龄组总患病率随着年龄增大呈增高趋势(≥55岁组略有下降):15 ～ 24岁8.8％(7/192),25 ～ 34岁20.4％(44/225),35 ～44岁26.5％(77/291),45～54岁41.7％(55/132),≥55岁34.1％(31/91),差异有统计学意义(P＜0.01).(3)PTSD患者自愿接受治疗23例(18.3％),2例完成治疗.结论 相关区域PTSD和重性抑郁障碍患病率位于突发群体事件后精神障碍的前两位.高暴露者精神障碍总患病率高于低暴露者,年龄＜55岁人群精神障碍总患病率随年龄增大呈增高趋势.社区PTSD患者治疗依从性差.%Objective To understand the prevalence rate and factors to mental disorder in residents aged 15 years and older along the Zhong-wan street in the Urumqi after the emergency of group injury.To provide the basis for the community mental health service especially psychological crisis intervention.Methods The residents aged 15 years and older along the Zhong-wan street were assessed with the DSMⅣ-TR for making diagnosis of axis Ⅰ disorder from September 5 to November 5 in 2009.Results In the 931 residents completed the surveys

Tänavuse Berlinale filmid süvenevad ihulähedasse / Grete Nootre

Index Scriptorium Estoniae

Nootre, Grete

2006-01-01

56. Berliini filmifestivali programmidest ja filmidest - USA mängufilm "A Prairie Home Companion" : režissöör Robert Altman, saksa mängufilm "Vaba tahe" ("Der Freie Wille") : režissöör Matthias Glasner, austraalia-inglise "Ettepanek" ("The Proposition") : stsenarist ja helilooja Nick Cave : režissöör John Hillcoat

(DEPSCOR FY 09) Obfuscation and Deobfuscation of Intent of Computer Programs

Science.gov (United States)

2012-12-21

increased as the malware distribution mechanism has moved to the web through infected sites. In this use a site is hacked so as to distribute malware to...Simpósio Brasileiro em Segurança da Informaçao e de Sistemas Computacionais (2009). (Chen et al., 2012) Jundong Chen, Matthias R. Brust, Vir V. Phoha

Lectures on algebraic model theory

CERN Document Server

Hart, Bradd

2001-01-01

In recent years, model theory has had remarkable success in solving important problems as well as in shedding new light on our understanding of them. The three lectures collected here present recent developments in three such areas: Anand Pillay on differential fields, Patrick Speissegger on o-minimality and Matthias Clasen and Matthew Valeriote on tame congruence theory.

Svoboda na Maarjamjagi

Index Scriptorium Estoniae

2008-01-01

Eesti Kunstiakadeemia skulptuuritudengite workshopil loodud vabaduse monumentide näitus Eesti Ajaloomuuseumi pargis Maarjamäel. Projekt أVabaduse monumendidؤ on osa Eesti Ajaloomuuseumi näitusest أIseolemise tahe. 90 aastat Eesti Vabariikiؤ Maarjamäe lossis. Oma töid eksponeerivad skulptuuritudengid Marit Mardla, Matthias-Jakob Sildnik, Liis Dvorjanski, Jekaterina Kultajeva, Li Yang ja teised

Eesti fenomen Alexanderi tehnika maailmas / Aivi Parijõgi

Index Scriptorium Estoniae

Parijõgi, Aivi, 1967-

2007-01-01

Alexanderi tehnikast. 2006. aastal EMTA lavakunstikoolis Alexanderi tehnika looja Frederick Matthias Alexander'i sünnipäeva (20.01) puhul toimunud workshopist. Vestlusringis osalevad EMTA Lavakunstikoolis Alexanderi tehnikat õpetav Maret Mursa Tormis, näitleja ja laulja Kärt Tomingas, pedagoog Celia Roose ning Alexanderi tehnika õpetajad mujalt - Dorothea Magonet, Steven Shaw, Masoumeh Atabaki Melrose, Ken Thompson

Poliitiliselt korrektselt on raske sündimust suurendada / Villu Zirnask

Index Scriptorium Estoniae

Zirnask, Villu, 1966-

2008-01-01

Autor käsitleb majandusteadlaste Vincenzo Galasso, Roberta Gatti ja Paola Profeta ning Matthias Doepke, Moshe Hazani ja Yishay D. Maozi sündimusteemalist uuringut ning järeldab, et praegustes tingimustes on võimatu samasugust beebibuumi esile kutsuda, kui oli 1950. aastatel. Diagramm: Sündimuse määra trend Eestis, Soomes ja Saksamaal 1950-2005

Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery

Directory of Open Access Journals (Sweden)

Lian H

2011-12-01

Full Text Available He Lian1, Jin Sun1, Yan Ping Yu1, Yan Hua Liu2, Wen Cao1, Yong Jun Wang1, Ying Hua Sun1, Si Ling Wang1, Zhong Gui He11School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Ningxia, People's Republic of ChinaBackground: Nowadays, many cytotoxic anticancer drugs exhibit low solubility and poor tumor selectivity, which means that the drug formulation is very important. For example, in the case of paclitaxel (PTX, Cremophor EL® (BASF, Ludwigshafen, Germany needs to be used as a solubilizer in its clinical formulation (Taxol®, Bristol-Myers Squibb, New York, NY, although it can cause serious side effects. Nanomicellar systems are promising carriers to resolve the above problems, and the polymer chosen is the key element.Methods: In this study, a novel amphiphilic chitosan/vitamin E succinate (CS-VES copolymer was successfully synthesized for self-assembling polymeric micelles. Proton nuclear magnetic resonance spectroscopy and infrared were used to characterize the molecular structure of the copolymer. The PTX-loaded CS-VES polymeric micelles (PTX-micelles were characterized by dynamic light scattering, transmission electron microscopy, X-ray diffraction, and differential scanning calorimetry.Results: The critical micelle concentration of CS-VES was about 12.6 µg/mL, with the degree of amino group substitution being 20.4%. PTX-micelles were prepared by a nanoprecipitation/dispersion technique without any surfactant being involved. PTX-micelles exhibited a drug loading as high as 21.37% and an encapsulation efficiency of 81.12%, with a particle size ranging from 326.3 to 380.8 nm and a zeta potential of +20 mV. In vitro release study showed a near zero-order sustained release, with 51.06%, 50.88%, and 44.35% of the PTX in the micelles being released up to 168 hours at three drug loadings of 7.52%, 14.09%, and 21.37%, respectively. The cellular uptake

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Cheng-Li Yao. Articles written in Journal of Chemical Sciences. Volume 121 Issue 1 January 2009 pp 89-93 Full Papers. Sucrose/bovine serum albumin mediated biomimetic crystallization of calcium carbonate · Cheng-Li Yao Wang-Hua Xu Ai-Min Ding Jin-Mao Zhu.

Jiná avantgarda? Poznámky

Czech Academy of Sciences Publication Activity Database

Vojtěch, Daniel

Roč. 56, č. 5 ( 2008 ), s. 709-713 ISSN 0009-0468 Institutional research plan: CEZ:AV0Z90560517 Keywords : Czech literature * Avant-garde * modernism Subject RIV: AJ - Letters, Mass-media, Audiovision

A Study of GaAsSb Nanowires by Molecular Beam Epitaxy for Near IR Applications

Science.gov (United States)

2015-09-18

Mosca, S. Franchi , P. Frigeri, E. Gombia, A. Carnera, M. Peroni, Mater. Science and Eng. B 80, 32 (2001). 1 Appendix C Pavan...Hossain N, Hild K, Jin S R, Sweeney S J, Yu S Q, Johnson S R, Ding D and Zhang Y H 2010 Photonics Global Conference IEEE 1 14 [3] Hwang J S, Tsai J T, Su

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

The extended (′/)-expansion method and travelling wave solutions for the perturbed nonlinear Schrödinger's equation with Kerr law nonlinearity · Zaiyun Zhang Jianhua Huang Juan Zhong .... pp 1075-1084 Research Articles. Performance evaluation of self-breakdown-based single-gap plasma cathode electron gun.

Kaks uut näitust 24 tunni galeriis

Index Scriptorium Estoniae

2003-01-01

Aadressil www.kunstikeskus.ee väljapanekud "Suur Hiina naeratus" hiina kunstnike - Song Haizeng, Du Xinjian, Xue Jiye, Wang Jing, Wu Meng Chun, Zhong Biao - töödest ja "Raffa oma galerii" kunstilehekülge külastanud inimeste online-joonistusmasina abiga joonistatud piltidest

Functionally Graded Material: An overview

CSIR Research Space (South Africa)

Mahamood, RM

2012-07-01

Full Text Available -3146. [50] X. Jin, L. Wu, L. Guo, H. Yu, and Y. Sun, ?Experimental investigation of the mixed-mode crack propagation in ZrO2/NiCr functionally graded materials,? Engineering Fracture Mechanics, vol. 76(12), (2009), pp. 1800-1810. [51] Z. Cheng, D. Gao... by stable crack growth,? Engineering Fracture Mechanics, vol.72(15), (2005), pp. 2359-2372. [47] Z.-H. Jin, and R.H. Dodds Jr, ?Crack growth resistance behavior of a functionally graded material: computational studies,? Engineering Fracture Mechanics...

Statistical Properties of Gamma-Ray Burst Host Galaxies Jie-Min ...

Indian Academy of Sciences (India)

Statistical Properties of Gamma-Ray Burst Host Galaxies. Jie-Min Chen1, Jin Zhang2,3, ... of GRB host galaxies and explore possible correlations between these properties. We also investigate possible cosmic ... hydrogen column density for the GRB host galaxies in our sample. 6.295. The stellar masses are mainly in the ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. Lingchen Guo. Articles written in Journal of Genetics. Volume 81 Issue 1 April 2002 pp 13-17 Perspectives. Cloning, chromosome localization and features of a novel human gene, MATH2 · Lingchen Guo Min Jiang Yushu Ma Haipeng Cheng Xiaohua Ni Yangsheng Jin Yi Xie Yumin ...

Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension

Directory of Open Access Journals (Sweden)

Ahn KT

2016-04-01

Full Text Available Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea Objectives: Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. Methods: Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg were enrolled. Central blood pressure and radial augmentation index (AIx corrected for a heart rate of 75 bpm (radial AIx 75 were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension. Results: A total of 203 patients were enrolled, of whom men numbered 101 (49.7%. The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005, a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R2=0.428, β=6.237, 95% confidence interval [CI] for women 1.480–10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively. Conclusion: In patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75. Keywords: hypertension, augmentation index, height, sex

German-austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn - update 2008

Directory of Open Access Journals (Sweden)

Buchholz Bernd

2009-11-01

Full Text Available Abstract German-Austrian recommendations for HIV1-therapy in pregnancy - Update 2008 Bernd Buchholz (University Medical Centre Mannheim, Pediatric Clinic, Matthias Beichert (Mannheim, Gynecology and Obstetrics Practice, Ulrich Marcus (Robert Koch Institute, Berlin, Thomas Grubert, Andrea Gingelmaier (Gynecology Clinic of the Ludwig Maximilians University of Munich, Dr. med. Annette Haberl (HIV-Department, J. W. Goethe-University Hospital, Frankfurt, Dr. med. Brigitte Schmied (Otto-Wagner Spital, Wien. In Germany during the last years about 200-250 HIV1-infected pregnant women delivered a baby each year, a number that is currently increasing. To determine the HIV-status early in pregnancy voluntary HIV-testing of all pregnant women is recommended in Germany and Austria as part of prenatal care. In those cases, where HIV1-infection was known during pregnancy, since 1995 the rate of vertical transmission of HIV1 was reduced to 1-2%. This low transmission rate has been achieved by the combination of anti-retroviral therapy of pregnant women, caesarean section scheduled before onset of labour, anti-retroviral post exposition prophylaxis in the newborn and refraining from breast-feeding by the HIV1-infected mother. To keep pace with new results in research, approval of new anti-retroviral drugs and changes in the general treatment recommendations for HIV1-infected adults, in 1998, 2001, 2003 and 2005 an interdisciplinary consensus meeting was held. Gynaecologists, infectious disease specialists, paediatricians, pharmacologists, virologists and members of the German AIDS Hilfe (NGO were participating in this conference to update the prevention strategies. A fifth update became necessary in 2008. The updating process was started in January 2008 and was terminated in September 2008. The guidelines provide new recommendations on the indication and the starting point for HIV-therapy in pregnancies without complications, drugs and drug combinations to be

Freies Geleit für Edward Snowden? / Matthias Friehe, Christopher Lipp

Index Scriptorium Estoniae

Friehe, Matthias

2014-01-01

Parlamendi uurimiskomisjoni ette kutsutavate tunnistajate julgeoleku tagamisest Edward Snowdeni juhtumi põhjal; kurjategija väljaandmiskohustusest ja tema karistuse käsitlusest Saksa karistusseadustiku järgi

Is "Yin-Yang Balancing" Superior to Ambidexterity as an Approach to Paradox Management?

DEFF Research Database (Denmark)

Li, Xin

2018-01-01

) of the Confucian principle of Zhong-Yong that is largely compatible with Aristotle’s doctrine of the mean. Second, at the practical level, his BYin-Yang balancing^ solution, while being different from the structural ambidexterity approach, is compatible with the contextual ambidexterity approach. These first two...

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences. Samira Mansour. Articles written in Journal of Biosciences. Volume 38 Issue 4 November 2013 pp 815-823 Review. Casuarina glauca: A model tree for basic research in actinorhizal symbiosis · Chonglu Zhong Samira Mansour Mathish Nambiar-Veetil Didier Bogusz Claudine ...

KDM2B overexpression correlates with poor prognosis and regulates glioma cell growth

OpenAIRE

Wang, Yiwei; Zang, Jin; Zhang, Dongyong; Sun, Zhenxiang; Qiu, Bo; Wang, Xiaojie

2018-01-01

Yiwei Wang,1 Jin Zang,1 Dongyong Zhang,2 Zhenxiang Sun,1 Bo Qiu,2 Xiaojie Wang1 1Department of Human Anatomy, Shenyang Medical College, Huanggu District, Shenyang City, 2Department of Neurosurgery, First Affiliated Hospital of China Medical University, Heping District, Shenyang City, Liaoning Province, ChinaBackground: Gliomas are one of the most lethal cancers in the human central nervous system. Despite clinical treatment advancements, the prognosis of patients with glioma remains ...

Atomic carbon chains as spin-transmitters: An ab initio transport study

DEFF Research Database (Denmark)

Fürst, Joachim Alexander; Brandbyge, Mads; Jauho, Antti-Pekka

2010-01-01

An atomic carbon chain joining two graphene flakes was recently realized in a ground-breaking experiment by Jin et al. (Phys. Rev. Lett., 102 (2009) 205501). We present ab initio results for the electron transport properties of such chains and demonstrate complete spin-polarization of the transmi......An atomic carbon chain joining two graphene flakes was recently realized in a ground-breaking experiment by Jin et al. (Phys. Rev. Lett., 102 (2009) 205501). We present ab initio results for the electron transport properties of such chains and demonstrate complete spin...

The Ser311Cys variation in the paraoxonase 2 gene increases the ...

Indian Academy of Sciences (India)

Supplementary data: The Ser311Cys variation in the paraoxonase 2 gene increases the risk of type 2 diabetes in northern Chinese. Yanchun Qu, Ze Yang, Feng Jin, Liang Sun, Chuanfang Zhang, Linong Ji, Hong Sun, Binyou Wang and Li Wang. J. Genet. 87, 165–169. Table 1. Clinical characteristics of case and control.

Compound mitochondrial DNA mutations in a neurological patient ...

Indian Academy of Sciences (India)

Compound mitochondrial DNA mutations in a neurological patient with ataxia, myoclonus and deafness. Ji Hoon Park, Bo Ram Yoon, Hye Jin Kim, Phil Hyu Lee, Byung-Ok Choi and Ki Wha Chung. J. Genet. 93, 173–177. Table 1. Variations from the whole mtDNA sequence in the AMDF patient. Mutation. Report. Locus/ ...

Transcriptome analysis and ultrastructure observation reveal that hawthorn fruit softening is due to cellulose/hemicellulose degradation

Directory of Open Access Journals (Sweden)

Jiayu Xu

2016-10-01

Full Text Available Softening, a common phenomenon in many fruits, is a well coordinated and genetically determined process. However, the process of flesh softening during ripening has rarely been described in hawthorn. In this study, we found that ‘Ruanrou Shanlihong 3 Hao’ fruits became softer during ripening, whereas ‘Qiu JinXing’ fruits remained hard. At late developmental stages, the firmness of ‘Ruanrou Shanlihong 3 Hao’ fruits rapidly declined, and that of ‘Qiu JinXing’ fruits remained essentially unchanged. According to transmission electron microscopy (TEM, the middle lamella of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruit flesh was largely degraded as the fruits matured. Microfilaments in ‘Qiu JinXing’ flesh were arranged close together and were deep in color, whereas those in ‘Ruanrou Shanlihong 3 Hao’ fruit flesh were arranged loosely, partially degraded and light in color. RNA-Seq analysis yielded approximately 46.72 Gb of clean data and 72,837 unigenes. Galactose metabolism and pentose and glucuronate interconversions are involved in cell wall metabolism, play an important role in hawthorn texture. We identified 85 unigenes related to the cell wall between hard- and soft-fleshed hawthorn fruits. Based on data analysis and real-time PCR, we suggest that β-GAL and PE4 have important functions in early fruit softening. The genes Ffase, Gns, α-GAL, PE63, XTH and CWP, which are involved in cell wall degradation, are responsible for the different textures of hawthorn fruits. Thus, we hypothesize that the different textures of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruits at maturity mainly result from cellulose/hemicelluloses degradation rather than from lamella degradation. Overall, we propose that different types of hydrolytic enzymes in cells interact to degrade the cell wall, resulting in ultramicroscopic Structure changes in the cell wall and, consequently, fruit softening. These results provide

影响公益众筹中项目筹款能力的一些相关因素--以众筹网为例%Some Related Factors Affecting the Ability to Raise Funds in the Crowdfunding of the Public Service---A Case Study of the ZhongChou Network

Institute of Scientific and Technical Information of China (English)

苟爱萍; 田江

2016-01-01

随着众筹融资和“互联网＋”的发展，公益众筹开始兴起，文中通过爬虫软件获取了截至2016年6月22日众筹网所有成功结束的筹款项目的数据，通过数据分析发现了不同性质的公益项目在众筹过程中具有不同的优势，并且通过SPSS进行了数据间简单的相关性分析，发现了影响公益众筹能力的一些相关性因素和非相关因素，研究了项目信息的透明度，回报捐助的方式以及关注度对一个公益筹款项目的影响。%With the development of the Crowdfunding and“Internet plus”,the Crowdfunding of the public service begin to develop.This paper achieved all the datas of the successful public service projects in the ZhongChou network until June 22,2016 using the crawler software.Through the data analysis found that the different nature of the public service projects in the process of raising the fund has a different advantage,and through the simple correlation analysis using SPSS,found some related factors and non-related factors that affect the ability to raise fund in Crowdfunding of the public service,the influence of the transparency of project information,the way of return and the degree of concern on a public service project.

On the use of the stabilised Q1P0 element for geodynamical simulations and why this is a bad choice for buyoancy-driven flows.

Science.gov (United States)

Thieulot, Cedric

2016-04-01

Many Finite Element geodynamical codes (Fullsack,1995; Zhong et al., 2000; Thieulot, 2011) are based on bi/tri­-linear velocity constant pressure element (commonly called Q1P0), because of its ease of programming and rather low memory footprint, despite the presence of (pressure) checker­board modes. However, it is long known that the Q1P0 is not inf­-sup stable and does not lend itself to the use of iterative solvers, which makes it a less­ than­ ideal candidate for high resolution 3D models. Other attempts were made more recently (Burstedde et al., 2013; Le Pourhiet et al., 2012) with the use of the stabilised Q1Q1 element (bi/tri­-linear velocity and pressure). This element, while also attractive from an implementation and memory standpoint, suffers a major drawback due to the artificial compressibility introduced by the polynomial projection stabilization. These observations have shifted part of the community towards the Finite Difference Method while the remaining part is now embracing inf­sup stable second­ order elements [May et al., 2015; Kronbichler,2012). Rather surprinsingly, a third option exists when it comes to first ­order elements in the form of the stabilised Q1P0 element, but virtually no literature exists concerning its use for geodynamical applications. I will then recall the specificity of the stabilisation and will carry out a series of benchmark experiments and geodynamical tests to assess its performance. While being shown to work as expected in benchmark experiments, the stabilised Q1P0 element turns out to introduce first-order numerical artefacts in the velocity and pressure solutions in the case of buoyancy-driven flows. Burstedde, C., Stadler, G., Alisic, L., Wilcox, L. C., Tan, E., Gurnis, M., & Ghattas, O. (2013). Large­scale adaptive mantle convection simulation. Geophysical Journal International, 192(3), 889­906. Fullsack, P. (1995). An arbitrary Lagrangian­Eulerian formulation for creeping flows and its application in

A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

Science.gov (United States)

2015-07-21

Hybrid Biosensor Jieun Lee1,2, Jaeman Jang1, Bongsik Choi1, Jinsu Yoon1, Jee-Yeon Kim3, Yang-Kyu Choi3, Dong Myong Kim1, Dae Hwan Kim1 & Sung-Jin Choi1...This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response...of field-effect-transistor (FET)-based biosensors . The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential

Bu-Shen-Ning-Xin Decoction ameliorated the osteoporotic phenotype of ovariectomized mice without affecting the serum estrogen concentration or uterus

OpenAIRE

Wang, Ling; Qiu,Xue-Min; Gui,Yu-Yan; Xu,Yingping; Gober,Hans-Jürgen; Li,Da-Jin

2015-01-01

Ling Wang,1,2,* Xue-Min Qiu,1,2,* Yu-Yan Gui,1,2 Ying-Ping Xu,1,2 Hans-Jürgen Gober,3 Da-Jin Li1 1Laboratory for Reproductive Immunology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, 2Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, People’s Republic of China; 3Department of Pharmacy, Wagner Jauregg Hospital and Children’s Hospital, Linz, Austria *These authors contribute...

Study on Hongzhou kiln porcelains of successive dynasties by NAA

International Nuclear Information System (INIS)

Feng Xiangqian; Feng Songlin; Quan Kuishan

2005-01-01

400 sherds were collected from Hongzhou Kiln covering 8 periods from Eastern Han to Late Tang Dynasty/the Five Dynasties and their bodies were analysed by NAA. The results show that the elemental contents in different samples are quite distinct, even for those in the same period. It means no single element can be used as 'fingerprint' to distinguish the period. The curves of the contents of Na, Rb, Ba and Fe varying with time are very similar, like 'U' shape. As a colorant element, the content of Fe is consistent with the color of the body. The higher content of Fe is, the more dark of the body is. The outcome of principal component analysis (PCA) indicates that most of the sherds can be classified into 5 groups: (1) Eastern Han and Eastern Wu; (2) Western Jin, Eastern Jin and Southern Dynasties; (3) Sui; (4) Early Tang and Middle Tang; (5) Late Tang and Five Dynasties. (authors)

The extended (G/G)-expansion method and travelling wave ...

Indian Academy of Sciences (India)

Home; Journals; Pramana – Journal of Physics; Volume 82; Issue 6. The extended (′/)-expansion method and travelling wave solutions for the perturbed nonlinear Schrödinger's equation with Kerr law nonlinearity. Zaiyun Zhang Jianhua Huang Juan Zhong Sha-Sha Dou Jiao Liu Dan Peng Ting Gao. Research Articles ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. YAN HUI GENG. Articles written in Sadhana. Volume 43 Issue 3 March 2018 pp 34. Spectral element method for wave propagation on irregular domains · YAN HUI GENG GUO LIANG QIN JIA ZHONG ZHANG · More Details Abstract Fulltext PDF. A spectral element approximation of acoustic ...

Journal of Astrophysics and Astronomy | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Astrophysics and Astronomy. Zhao Wen-juan. Articles written in Journal of Astrophysics and Astronomy. Volume 38 Issue 2 June 2017 pp 21 Research Article. Classification of Stellar Spectra with Fuzzy Minimum Within-Class Support Vector Machine · Liu Zhong-bao Song Wen-ai Zhang Jing ...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Hai-Liang Zhu. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 463-470. Synthesis, antimicrobial activity of lamotrigine and its ammonium derivatives · Yong Qian Peng-Cheng Lv Lei Shi Rui-Qin Fang Zhong-Cheng Song Hai-Liang Zhu.

Exploiting HPC Platforms for Metagenomics: Challenges and Opportunities (MICW - Metagenomics Informatics Challenges Workshop: 10K Genomes at a Time)

Energy Technology Data Exchange (ETDEWEB)

Canon, Shane

2011-10-12

DOE JGI's Zhong Wang, chair of the High-performance Computing session, gives a brief introduction before Berkeley Lab's Shane Canon talks about "Exploiting HPC Platforms for Metagenomics: Challenges and Opportunities" at the Metagenomics Informatics Challenges Workshop held at the DOE JGI on October 12-13, 2011.

A review of the discovery of SM-like Higgs boson in H→γγ decay ...

Indian Academy of Sciences (India)

300, Zhongda Rd, Zhongli District, Taoyuan City, Taiwan 320. ∗ ... developed by the CMS experiment, but also present the latest results of the ATLAS ... mated that with a sophisticated multivariate analysis. (MVA) .... The signal region of the search consists of collision ... case is the expected number of signal events, assum-.

Kaunis ja õudne : Raamaturida / Arno Oja

Index Scriptorium Estoniae

Oja, Arno, 1950-

1995-01-01

Beer, Natalie. Meister Mathis : Matthias Grünewaldi romaan; Pezold, Leopold. Kolme Eestimaa kunstniku rännuaastad; Vint, Maara. Vint, Eve-Maria. Võlulehvik; Seton, Anya. Katherine, 2.osa; Suosalmi, Kerttu-Kaarina. Õnnekütt; Herriott, James. Koerajutud; Laos, Ester. Õhtuks koju; Ewers, Hanns Heinz. Alraune; King, Stephen. Raamatukogupolitseinik; Pabut, Talvo. Surma suflöör; Loon, Paul van. Õuduste käsiraamat

Berliinis poole peal / Endel Link

Index Scriptorium Estoniae

Link, Endel

2006-01-01

56. Berliini filmifestivalist ja filmidest - USA mängufilm "A Prairie Home Companion" : režissöör Robert Altman, saksa mängufilmid "Vaba tahe" ("Der Freie Wille") : režissöör Matthias Glasner ja "Elementaarosakesed" ("Elementarteilchen") : režissöör Oskar Roehler, inglise-kanada mängufilm "Lumekeeks" ("Snowcake") : režissöör Marc Evans

Föderaalne Keskkonnaagentuur Dessaus

Index Scriptorium Estoniae

2008-01-01

Büroohoone Dessau endisel tööstusalal. Linnaehituslikust lahendusest ja ökoloogilistest nõuetest hoonele. Loetletud hoone säästlikkuse põhipunktid. Projekteerija: Sauerbruch Hutton (Berliin). Autorid: Matthias Sauerbruch, Louisa Hutton, Juan Lucas Young, Jens Ludloff. Konstruktor: Krebs & Kiefer (Berliin). Energeetika ja keskkonnatehnika: Zibell Willner & Partner (Köln/Berliin). Projekt: 2001, valmis: 2005. Asendiplaan, 2 värv. välisvaadet, sisevaade

Vremja Dostojevskogo / Boris Tuch

Index Scriptorium Estoniae

Tuch, Boris, 1946-

2007-01-01

Dostojevski kangelased Eesti teatrilaval: "Onu unenägu" Vene Teatris (lavastaja Mihhail Tshumatshenko), Matthias Andersoni "Kuritöö, kodutööd, karistus, raha, pensionäri tapmine" Teises Teatris (lavastajad Erki Aule ja Artjom Garejev), Eesti - Läti - Leedu vene teatrite koostööprojekt "Vene naer" (lavastaja Roman Kozak), "Sortsid" Eesti Draamateatris (lavastaja Hendrik Toompere jun.), "Krokodill" Vana Baskini Teatris (lavastaja Mark Rozovski)

Dostojevski aeg / Boris Tuch ; tõlk. Madis Kolk

Index Scriptorium Estoniae

Tuch, Boris, 1946-

2007-01-01

Dostojevski kangelased Eesti teatrilaval: "Onu unenägu" Vene Teatris (lavastaja Mihhail Tshumatshenko), Matthias Andersoni "Kuritöö, kodutööd, karistus, raha, pensionäri tapmine" Drugoi Teatr (lavastajad Erki Aule ja Artjom Garejev), Eesti - Läti - Leedu vene teatrite koostööprojekt "Russki smehh" (lavastaja Roman Kozak), "Sortsid" Eesti Draamateatris (lavastaja Hendrik Toompere jun.), "Krokodill" Vana Baskini Teatris (lavastaja Mark Rozovski)

Exposure to waterborne Cu inhibits cutaneous Na⁺ uptake in post-hatch larval rainbow trout (Oncorhynchus mykiss).

Science.gov (United States)

Zimmer, Alex M; Brauner, Colin J; Wood, Chris M

2014-05-01

In freshwater rainbow trout (Oncorhynchus mykiss), two common responses to acute waterborne copper (Cu) exposure are reductions in ammonia excretion and Na(+) uptake at the gills, with the latter representing the likely lethal mechanism of action for Cu in adult fish. Larval fish, however, lack a functional gill following hatch and rely predominantly on cutaneous exchange, yet represent the most Cu-sensitive life stage. It is not known if Cu toxicity in larval fish occurs via the skin or gills. The present study utilized divided chambers to assess cutaneous and branchial Cu toxicity over larval development, using disruptions in ammonia excretion (Jamm) and Na(+) uptake (Jin(Na)) as toxicological endpoints. Early in development (early; 3 days post-hatch; dph), approximately 95% of Jamm and 78% of Jin(Na) occurred cutaneously, while in the late developmental stage (late; 25 dph), the gills were the dominant site of exchange (83 and 87% of Jamm and Jin(Na), respectively). Exposure to 50 μg/l Cu led to a 49% inhibition of Jamm in the late developmental stage only, while in the early and middle developmental (mid; 17 dph) stages, Cu had no effect on Jamm. Jin(Na), however, was significantly inhibited by Cu exposure at the early (53% reduction) and late (47% reduction) stages. Inhibition at the early stage of development was mediated by a reduction in cutaneous uptake, representing the first evidence of cutaneous metal toxicity in an intact aquatic organism. The inhibitions of both Jamm and Jin(Na) in the late developmental stage occurred via a reduction in branchial exchange only. The differential responses of the skin and gills to Cu exposure suggest that the mechanisms of Jamm and Jin(Na) and/or Cu toxicity differ between these tissues. Exposure to 20μg/l Cu revealed that Jamm is the more Cu-sensitive process. The results presented here have important implications in predicting metal toxicity in larval fish. The Biotic Ligand Model (BLM) is currently used to predict

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

OpenAIRE

Park G; Bae SH; Park W; Han S; Park M; Shin S; Shin YG; Yim DS

2017-01-01

Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI) study may be a ...

Author Details

African Journals Online (AJOL)

Nie, Zhong. Vol 14, No 5 (2017) - Articles Neuroprotective effect corilagin in spinal cord injury rat model by inhibiting nuclear factor-kB, inflammation and apoptosis. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

Browse Title Index

African Journals Online (AJOL)

Items 4451 - 4500 of 11090 ... Lingling Zhao, Jinping Wu, Ying Diao, Zhongli Hu. Vol 10, No 39 (2011), Embryogenesis of Gentiana straminea and assessment of genetic stability of regenerated plants using inter simple sequence repeat (ISSR) marker, Abstract PDF. T He, L Yang, Z Zhao. Vol 10, No 45 (2011), Emergence and ...

Reference: 759 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 759 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18434608i Guan Yue-Feng...s. 2 852-63 18434608 2008 Jun Plant physiology Gao Ju-Fang|Guan Yue-Feng|Huang Xue-Yong|Yang Zhong-Nan|Zhang Hong-Xia|Zhu Jun

Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers

Directory of Open Access Journals (Sweden)

Fan HX

2015-07-01

Full Text Available Hai-Xia Fan,1 Yan Chen,1 Bo-Xiong Ni,1 Shan Wang,1 Miao Sun,2 Dong Chen,2 Jin-Hua Zheng11Department of Anatomy, Basic Medical Science College, 2Department of Oral and Maxillofacial Surgery, Stomatological Hospital, Harbin Medical University, Harbin, People’s Republic of ChinaBackground: Matrix metalloproteinase (MMP-1 degrades type I collagen of the extracellular matrix and also activates protease activated receptor (PAR-1 to induce angiogenesis. The aims of this study were to evaluate microvessel density (MVD and the expression of PAR-1 and MMP-1 in oral squamous cell carcinoma (SCC specimens with different patterns of invasion (POI and to evaluate their association with clinical outcomes.Methods: Seventy-four surgically obtained oral SCC samples were classified by POI according to hematoxylin-eosin staining. MVD and the localization and intensity of PAR-1 and MMP-1 expression were detected by immunohistochemistry.Results: Of the 74 oral SCC samples, 18, 5, 34, and 17 showed type I, II, III, and IV POI, respectively. MVD and expression levels of MMP-1 and PAR-1 differed between POI types I–II and POI types III–IV. Patients with low tumor expression of MMP-1 and PAR-1 and low MVD had a longer survival time than those with high tumor expression of MMP-1 and PAR-1. Moreover, the survival time of patients with POI types III–IV was shorter than that of patients with POI types I–II.Conclusion: POI combined with expression levels of MMP-1 and PAR-1 may be a valuable tool for assessing the clinical prognosis of patients with oral SCC.Keywords: oral squamous cell carcinoma, pattern of invasion, immunohistochemistry, clinical outcomes

Nanotubular surface modification of metallic implants via electrochemical anodization technique

OpenAIRE

Wang, Lu-Ning; Jin, Ming; Zheng, Yudong; Guan, Yueping; Lu, Xin; Luo, Jing-Li

2014-01-01

Lu-Ning Wang,1 Ming Jin,1 Yudong Zheng,1 Yueping Guan,1 Xin Lu,1 Jing-Li Luo21School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People’s Republic of China; 2Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, CanadaAbstract: Due to increased awareness and interest in the biomedical implant field as a result of an aging population, research in the field of implantable devices has grown rapidly in the...

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

OpenAIRE

Yoon, Seonghae; Lee, Howard; Kim, Tae-Eun; Lee, SeungHwan; Chee, Dong-Hyun; Cho, Joo-Youn; Yu, Kyung-Sang; Jang, In-Jin

2014-01-01

Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER...

Strengthening financial management, providing financial safeguard mechanism

International Nuclear Information System (INIS)

Sun Wumei

2010-01-01

This article reviewed the history of Zhong He Shanxi Uranium Enrichment Company, summarizing an efficient and systematical financial management method during both construction period and operational period of the company. It related to fundamental financial management structure building, integrated budgeting, fund management, cost management, asset management, tax planning and HR management. of financial staffs. (author)

Pinoresinol diglucoside exhibits protective effect on dexamethasone ...

African Journals Online (AJOL)

Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 ... Zhan-Feng Zhang, Ji-Kang Min, Dan Wang, Jian-Ming Zhong* .... mineral density meter (Beijing Zhongxi Yuanda ..... Svedbom A, Ivergård M, Hernlund E, Rizzoli R, Kanis JA. ... Pan Y, Niu Y, Li C, Zhai Y, Zhang R, Guo X, Mei Q. Du-.

Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model

Directory of Open Access Journals (Sweden)

Du Y

2017-11-01

Full Text Available Yang Du,1,2,* Ting Sun,3,* Xiaolong Liang,4,* Yuan Li,3 Zhengyu Jin,3 Huadan Xue,3 Yihong Wan,5 Jie Tian1,2 1CAS Key Laboratory of Molecular Imaging, 2The State Key Laboratory of Management and Control for Complex Systems, Institute of Automation, Chinese Academy of Sciences, 3Department of Radiology, Peking Union Medical College Hospital, 4Department of Ultrasound, Peking University Third Hospital, Beijing, China; 5Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA *These authors contributed equally to this work Abstract: An intraoperative technique to accurately identify microscopic tumor residuals could decrease the risk of positive surgical margins. Several lines of evidence support the expression and immunotherapeutic effect of PD-1 in breast cancer. Here, we sought to develop a fluorescence-labeled PD-1 probe for in vivo breast tumor imaging and image-guided surgery. The efficacy of PD-1 monoclonal antibody (PD-1 mAb as adjuvant immunotherapy after surgery was also assessed. PD-1-IRDye800CW was developed and examined for its application in tumor imaging and image-guided tumor resection in an immunocompetent 4T1 mouse tumor model. Fluorescence molecular imaging was performed to monitor probe biodistribution and intraoperative imaging. Bioluminescence imaging was performed to monitor tumor growth and evaluate postsurgical tumor residuals, recurrences, and metastases. The PD-1-IRDye800CW exhibited a specific signal at the tumor region compared with the IgG control. Furthermore, PD-1-IRDye800CW-guided surgery combined with PD-1 adjuvant immunotherapy inhibited tumor regrowth and microtumor metastases and thus improved survival rate. Our study demonstrates the feasibility of using PD-1-IRDye800CW for breast tumor imaging and image-guided tumor resection. Moreover, PD-1 mAb adjuvant immunotherapy reduces cancer recurrences and metastases emanating from tumor residuals. Keywords: PD-1, programmed cell

Portable Low Volume Therapy for Severe Blood Loss

Science.gov (United States)

2016-08-01

surgery. 1971;8(1):1-48. 13. Radogna F, Paternoster L, Albertini MC, Cerella C, Accorsi A, Bucchini A, Spadoni G, Diamantini G, Tarzia G, Nicola MD...Paternoster L, D’Alessio M, De Nicola M, Cerella C, Dicato M, Diederich M, Ghibelli L. Melatonin antagonizes the intrinsic pathway of apoptosis via...O’Neal‐Moffitt G, Jin J, Buzzeo R, Mamcarz M, Tan J, Cao C, Olcese JM, Arendash GW. Melatonin treatment restores mitochondrial function in

Chinese herbal dose in ancient and modern times: a comparative study.

Science.gov (United States)

He, Shimin

2013-04-01

Appropriate dose guarantees Chinese herb's safety and effectiveness. There are adult dose criteria for Chinese herbs in decoction in the Pharmacopoeia of the People's Republic of China (2010 Edition) at present. But Chinese herbs have been frequently used in much higher doses than the dose criteria. This study has been conducted to test the dependability of the dose criteria. Twenty Chinese herbs were selected as representatives and their adult doses in decoction in Bei Ji Qian Jin Yao Fang, a famous ancient literature, have been reviewed and compared with those in the Pharmacopoeia of the People's Republic of China (2010 Edition). The adult dose criteria for all these 20 Chinese herbs in the Pharmacopoeia of the People's Republic of China (2010 Edition) haven't covered those in Bei Ji Qian Jin Yao Fang. Furthermore, maximal adult doses in the dose criteria are much lower than those in Bei Ji Qian Jin Yao Fang. The dose criteria in the Pharmacopoeia of the People's Republic of China (2010 Edition) are not comprehensive enough. Studying ancient literatures is an effective method to gain precious Chinese herbs' dose data and helps for new dose criteria's establishment in the future.

Influence of Vinegar and Wine Processing on the Alkaloid Content and Composition of the Traditional Chinese Medicine Corydalis Rhizoma (Yanhusuo

Directory of Open Access Journals (Sweden)

Hongwei Wu

2014-08-01

Full Text Available Corydalis Rhizoma is the dried tuber of Corydalis yanhusuo W.T. Wang which is used in traditional Chinese medicine for pain relief and blood activation. Before being used in the clinics, C. yanhusuo is traditionally processed through dry-frying or frying with vinegar, wine or salt. In this study, eleven alkaloids from Corydalis Rhizoma, namely protopine (1, α-allocryptopine (2, tetrahydrocolumbamine (3, coptisine (4, palmatine (5, berberine (6, dehydrocorydaline (7, d,l-tetrahydropalmatine (8, tetrahydroberberine (9, corydaline (10 and tetrahydrocoptisine (11 were simultaneously quantified using a newly developed high performance liquid chromatography-diode array detector (HPLC-DAD method. The influence of vinegar and wine processing on the content of the main alkaloids of Corydalis Rhizoma was investigated. For this purpose, two common formulations with clinical application, namely the water decoction of Corydalis Rhizoma and its formula Jin Ling Zi San (combination of Corydalis Rhizoma and Toosendan Fructus were studied. In the two water decoctions, wine and vinegar processing increased the amount of tertiary alkaloids. The differences were more pronounced for Jin Ling Zi San, in which case the content of all tertiary alkaloids (compounds 1, 2, 3, 8, 9, 10, 11 was increased by wine processing.

Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction

Directory of Open Access Journals (Sweden)

Choi SJ

2014-12-01

Full Text Available Soo-Jin Choi,1 Jin-Ho Choy2 1Department of Food Science and Technology, Seoul Women's University, 2Center for Intelligent Nano Bio Materials (CINBM, Department of Bioinspired Science and Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, South Korea Abstract: Biokinetic studies of zinc oxide (ZnO nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, which is important for predicting the long-term toxic potential of nanoparticles. Biokinetic behaviors can be dependent on physicochemical properties, dissolution property in biological fluids, and nanoparticle–protein interaction. Moreover, the determination of biological fates of ZnO nanoparticles in the systemic circulation and tissues is critical in interpreting biokinetic behaviors and predicting toxicity potential as well as mechanism. This review focuses on physicochemical factors affecting the biokinetics of ZnO nanoparticles, in concert with understanding bioavailable fates and their interaction with proteins. Keywords: ZnO nanoparticles, biokinetics, distribution, excretion, fate, interaction

胡阿祥:《东晋南朝侨州郡县与侨流人口研究》%Axiang Hu, Dongjin Nanchao Qiao zhoujunxian yu qiaoliu renkou yanjiu

Institute of Scientific and Technical Information of China (English)

孔祥军

2010-01-01

@@ The epoch of the Wei, Jin and Southern and Northern dynasties was perhaps the most chaotic and complicated era in Chinese history, in terms of regime instability. Except for a short period of unification under the Western Jin, this era was marked by continuous division and confrontation. Accordingly, professional historians and amateur history lovers alike prefer to examine the unified and the powerful Han and Tang dynasties and are often unwilling to deal with this discordant and tumultuous time.However,the furious conflicts of this era actually promoted ethnic amalgamations,territorial exploits,cultural transmission and intellectual communication,therefore,an in-depth study of this period is not only worthwhile,but necessary.

CLONING AND SEQUENCING OF PGIP FROM ‘JIN SERIES’ ALMOND (PRUNUS DULCIS

Directory of Open Access Journals (Sweden)

Yuhu Han

2015-12-01

Full Text Available Specific primers synthesized according to conservative regions of polygalacturonase inhibiting protein (PGIP gene were used to amplify Prunus Dulcis genomic DNA by polymerase-chain reaction (PCR. Six bands (pgip1, pgip2, pgip3, pgip4, pgip5 and pgip6 of genes were obtained and cloned into PBS-T vector. According to the length of bands, 717bp, 864bp, 796bp were A1 (pgip1, pgip2, pgip3, A2 (pgip4, A4 (pgip5, pgip6, respectively. DNA sequences showed that the fragments taken together were the gene encoding PGIP. A2 and A3 contained two exons interrupted by one intron, which has GT-AG sequence. Its DNA and amino acid sequences were highly homologies to those from Prunus Persica; Prunus Salicina; Prunus Americana; Prunus Mume, respectively. A conserved lencinerial fragment exists in the derived protein sequence.

[Characteristics of mercury pollution in soil and atmosphere in Songhua River upstream Jia-pi-gou gold mining area].

Science.gov (United States)

Zhang, Gang; Wang, Ning; Wang, Yuan; Liu, Te; Ai, Jian-Chao

2012-09-01

In the studied area of Jia-pi-gou at the upstream area of Songhua River, algamation process has been applied as a dominant method to extract gold for more than one hundred and eighty years, resulting in severe mercury environmental pollution. The total mercury contents in the atmosphere and soil have been determined by mercury analyzer (Zeeman RA915+) and cold atomic absorption spectrophotometry (GB/T 17136-1997), respectively. To study the pollution characteristics of mercury in the soil and atmosphere, the mercury flux at the interface between the soil and the atmosphere of 4 sampling sites Lao-jin-chang, Er-dao-gou, Er-dao-cha and community of Jia-pi-gou have been determined with the method of dynamic flux chamber. Furthermore, linear regression analyses on the total mercury contents between soil and atmosphere have been carried out and the correlation coefficient of mercury exchange flux between soil and atmosphere and meteorological factors has been studied. The results are as follows: (1) The mean value of mercury content in the atmosphere is (71.08 +/- 38.22) ng x m(-3). (2) The mean value of mercury content in the soil is (0.913 1 +/- 0.040 8) mg x kg(-1); it shows remarkably positive correlation between the mercury contents in soil and in the atmosphere. (3) The mercury exchange flux between soil and atmosphere in different locations are Lao-jin-chang [(129.13 +/- 496.07) ng (m2 x h)(-1)], Er-dao-gou [(98.64 +/- 43.96) ng x (m2 x h)(-1)], Er-dao-cha [(23.17 +/- 171.23) ng x (m2 x h)(-1)], and community of Jia-pi-gou [(7.12 +/- 46.33) ng x (m2 x h)(-1)]. (4) Solar radiation is the major influential factor in the mercury exchange flux between the soil and atmosphere in Lao-jin-chang, Er-dao-cha and community of Jia-pi-gou. Solar radiation, air temperature and soil temperature jointly influence the process of the mercury exchange flux between the soil and atmosphere in Er-dao-gou. Under the disturbance of terrain, three noticeably distinctive trend features

Docetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy

OpenAIRE

Oh, Keun Sang; Kim, Kyungim; Yoon, Byeong Deok; Lee, Hye Jin; Park, Dal Yong; Kim, Eun-yeong; Lee, Kiho; Seo, Jae Hong; Yuk, Soon Hong

2016-01-01

Keun Sang Oh,1,* Kyungim Kim,1,* Byeong Deok Yoon,1 Hye Jin Lee,1 Dal Yong Park,1 Eun-yeong Kim,1 Kiho Lee,1 Jae Hong Seo,2 Soon Hong Yuk1,2 1College of Pharmacy, Korea University, Sejong, 2Biomedical Research Center, Korea University Guro Hospital, Guro-gu, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A mixture of docetaxel (DTX) and Solutol® HS 15 (Solutol) transiently formed nanodroplets when it was suspended in an aqueous medium. However, n...

Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects

OpenAIRE

Kang,Woo Youl; Seong,Sook Jin; Ohk,Boram; Gwon,Mi-Ri; Kim,Bo Kyung; La,Sookie; Kim,Hyun-Ju; Cho,Seungil; Yoon,Young-Ran; Yang,Dong Heon; Lee,Hae Won

2018-01-01

Woo Youl Kang,1,2,* Sook Jin Seong,1,* Boram Ohk,1,2 Mi-Ri Gwon,1,3 Bo Kyung Kim,1,2 Sookie La,4 Hyun-Ju Kim,3 Seungil Cho,1 Young-Ran Yoon,1,2 Dong Heon Yang,5 Hae Won Lee1 1Clinical Trial Center, Kyungpook National University Hospital, Daegu, Republic of Korea; 2Department of Biomedical Science, BK21 Plus KNU Bio-Medical Convergence Program for Creative Talent, Kyungpook National University Graduate School, Daegu, Republic of Korea; 3Department of Molecular Medicine, Cell and Matrix Resear...

The Cultural Revolution and Contemporary Chinese Art

Science.gov (United States)

Yang, Guey-Meei; Suchan, Tom

2009-01-01

Using this instructional resource, teachers can explore the impact of the Cultural Revolution (1966-1976) on contemporary art in mainland China with their students. The three artists Luo Zhongli (b. 1948), Xu Bing (b. 1955), and Wang Guangyi (b. 1957) came of age during the Cultural Revolution and are representative of a much larger number of…

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

pp 85-91 Research Article. Cloning and study of adult-tissue-specific expression of Sox9 in Cyprinus carpio · Du Qi-Yan Wang Feng-Yu Hua Hui-Ying Chang Zhong-Jie · More Details Abstract Fulltext PDF. The Sox9 gene is one of the important transcription factors in the development of many tissues and organs, particularly ...

Conference scene: DGVS spring conference 2009.

Science.gov (United States)

Kolligs, Frank Thomas

2009-10-01

The 3rd annual DGVS Spring Conference of the German Society for Gastroenterology (Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten) was held at the Seminaris Campus Hotel in Berlin, Germany, on 8-9 May, 2009. The conference was organized by Roland Schmid and Matthias Ebert from the Technical University of Munich, Germany. The central theme of the meeting was 'translational gastrointestinal oncology: towards personalized medicine and individualized therapy'. The conference covered talks on markers for diagnosis, screening and surveillance of colorectal cancer, targets for molecular therapy, response prediction in clinical oncology, development and integration of molecular imaging in gastrointestinal oncology and translational research in clinical trial design. Owing to the broad array of topics and limitations of space, this article will focus on biomarkers, response prediction and the integration of biomarkers into clinical trials. Presentations mentioned in this summary were given by Matthias Ebert (Technical University of Munich, Germany), Esmeralda Heiden (Epigenomics, Berlin, Germany), Frank Kolligs (University of Munich, Germany), Florian Lordick (University of Heidelberg, Germany), Hans Jorgen Nielsen (University of Copenhagen, Denmark), Anke Reinacher-Schick (University of Bochum, Germany), Christoph Röcken (University of Berlin, Germany), Wolff Schmiegel (University of Bochum, Germany) and Thomas Seufferlein (University of Halle, Germany).

Metabolic Signature of Antipsychotics used in the Treatment of Autism

Science.gov (United States)

2016-12-01

pediatric, adult, and geriatric patients with schizophrenia, bipolar disorder, major depression, post-traumatic stress disorder and autism [1, 2]. While most...Endocrine manifestations of eating disorders. J.Clin.Endocrinol.Metab 96, 333-343 60. Jin,H. et al. (2008) Impact of atypical antipsychotic therapy on...2010) Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis

New Perspectives on Chinese Herbal Medicine (Zhong-Yao) Research and Development

Science.gov (United States)

Pan, Si-Yuan; Chen, Si-Bao; Dong, Hong-Guang; Yu, Zhi-Ling; Dong, Ji-Cui; Long, Zhi-Xian; Fong, Wang-Fun; Han, Yi-Fan; Ko, Kam-Ming

2011-01-01

Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery. PMID:21785622

New Perspectives on Chinese Herbal Medicine (Zhong-Yao Research and Development

Directory of Open Access Journals (Sweden)

Si-Yuan Pan

2011-01-01

Full Text Available Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery.

1029: Tranexamic Acid for Pediatric Trauma

Science.gov (United States)

2014-12-01

parts. Of total 74 cases of rib fracture , the number of fracture between bone scan and CT are identical in only 9 cases (12%), and different in 65...OF BONE SCANNING IN THE DIAGNOSIS OF HIDDEN FRACTURE IN MAJOR TRAUMA PATIENTS Hang Joo Cho1, Sung Jeep Kim1, Jin Seok Baek2; 1The Catholic University...the hidden fracture . We investi- gated the usefulness of bone scan in the diagnosis of hidden fracture of major trauma patients. Methods: This study

[The textual research on the evolution of the toothbrush shape in ancient China].

Science.gov (United States)

Wu, Qiu-Peng

2012-05-01

Archaeological discovery demonstrates that the ancient plant hair brush first appeared in the Tang dynasty. According to the evolution of the shape of the head and handle of the toothbrush in ancient times, we can divide the evolution of the shapes into three major stages of development: (1) the Tang and the Five dynasties; (2) the Liao, Song, Jin, Yuan dynasties; (3) Ming, Qing and the Republic periods. The toothbrush heads and handles had no significant differences during the Tang and the Five dynasties. However, the shapes of them in the Liao, Song, Jin, Yuan dynasties are somewhat different. In the Ming and Qing and the republic of China periods, the shape of toothbrush head and handle had further refinement. Recently, some scholars raised doubts about the "plant hair toothbrush doctrine". They believe that the archaeological bone graft handle brush was used to wipe hair oil or clean water when washing and dressing. However, according to shape and function and ancient literature records, the archaeological bone graft handle brush should be a plant hair toothbrush used to clean and protect teeth.

Leaf Morphological Characters Can Be a Factor for Intra-Varietal Preference of Whitefly Bemisia tabaci (Hemiptera: Aleyrodidae among Eggplant Varieties.

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Abu Tayeb Mohammad Hasanuzzaman

Full Text Available The sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae MEAM1, is considered a serious pest of horticultural and many other crops. While eggplant (Solanum melongena is one of the most favored host plants, the whiteflies exhibit preferences among different varieties. We hypothesized that certain morphological leaf characteristics of different varieties, like leaf trichome density, trichome length, leaf lamina thickness and leaf color, may affect whitefly landing, feeding and oviposition. In this study, we investigated the variation in leaf morphological characters among selected eggplant varieties and evaluated the effect of these leaf characteristics in rendering eggplant varieties either susceptible or resistant to B. tabaci. We evaluated eight eggplant varieties in choice feeding tests, and we found that the varieties JinSheng Zilongchangqie (JSZ and H149 were the highly preferred varieties with the highest numbers of whitefly adults and eggs. Significantly lower numbers of whitefly adult eggs were found on the resistant variety Tuo Lu Bamu (TLB. The varieties JinGuangbo Luqie (JGL, JinGuangbo Ziquanqie (JGZ, DaYang Ziguanqie (DYZ, QinXing Ziguanqie (QXZ, and QinXing Niuxinqie (QXN were moderately favored by B. tabaci. Leaf trichome density, trichome length and leaf lamina thickness were positively correlated with numbers of whitefly adults and eggs. B. tabaci was less attracted to the leaves that reflect long and middle wavelength light (higher R and G values than to the bright green leaves (medium G value, but the short wavelength light (higher B value had no significant effect on whitefly preference. The degree of hue had a positive effect, and saturation and brightness had a negative effect on whitefly attraction.

Equations of discontinuity

International Nuclear Information System (INIS)

Wengenmayr, R.

2008-01-01

Max Planck founded quantum physics in 1900 - accidentally. In the years following 1920, many physicists developed modern quantum mechanics - through labyrinthine paths and amid intense disputes. This complex history is being studied by a group of historians working with JUeRGEN RENN, Director at the MAX PLANCK INSTITUTE FOR THE HISTORY OF SCIENCE, his colleague Christoph Lehner, and a group of physicists working with MATTHIAS SCHEFFLER, Director at the FRITZ HABER INSTITUTE. (orig.)

Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent

Directory of Open Access Journals (Sweden)

Lan Z

2015-06-01

Full Text Available Zujian Lan, Xiaoyu Xu, Wenkai Xu, Jin Li, Zengrong Liang, Xuefei Zhang, Ming Lei, Chunshun Zhao School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People’s Republic of China Abstract: To develop novel anti-ischemic stroke agents with better therapeutic efficacy and bioavailability, we designed and synthesized a series of 3-alkyl-2,3-dihydro-1H-isoindol-1-ones compounds (3a–i derivatives, one of which (3d exhibited the strongest inhibitory activity for the adenosine diphosphate-induced and arachidonic acid-induced platelet aggregation. This activity is superior to that of 3-n-butylphthalide and comparable with aspirin and edaravone. Meanwhile, 3d not only exhibited a potent activity in scavenging free radicals and improving the survival of HT22 cells against the reactive oxygen species-mediated cytotoxicity in vitro but also significantly attenuated the ischemia/reperfusion-induced oxidative stress in ischemic rat brains. Results from transient middle cerebral artery occlusion and permanent middle cerebral artery occlusion model, indicated that 3d could significantly reduce infarct size, improve neurobehavioral deficits, and prominently decrease attenuation of cerebral damage. Most importantly, 3d possessed a very high absolute bioavailability and was rapidly distributed in brain tissue to keep high plasma drug concentration for the treatment of ischemic strokes. In conclusion, our findings suggest that 3-alkyl-2,3-dihydro-1H-isoindol-1-ones, a novel series of compounds, might be candidate drugs for the treatment of acute ischemic strokes, and 3d may be a promising therapeutic agent for the primary and secondary prevention of ischemic stroke. Keywords: stroke, platelet aggregation, ischemia/reperfusion, middle cerebral artery occlusion, 3-alkyl-2,3-dihydro-1H-isoindol-1-ones

A system-level mechanistic investigation of traditional Chinese ...

African Journals Online (AJOL)

Xiao-Hong Gu* ... targets related to lung and stomach diseases were searched and screened to avoid duplication. ... Liu et al. Trop J Pharm Res, August 2017; 16(8): 1910. On account of this deficiency in knowledge, ..... Ru J, Li P, Wang J, Zhou W, Li B, Huang C, Li P, Guo Z, ... Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2013;.

Current contributions on the technical thermodynamics, power engineering and district heating supply. Special publication; Aktuelle Beitraege zur technischen Thermodynamik, Energietechnik und Fernwaermeversorgung. Sonderveroeffentlichung

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-03-15

Within the special publication under consideration, the German Heat and Power Association (Frankfurt (Main), Federal Republic of Germany) presents the following current contributions on the technical thermodynamics, power engineering and district heating supply: (1) Cellular metallic materials for innovative latent heat accumulator technologies (Jens Meinert); (2) Compressed air storage - technology, chances and problems (Rutger Kretschmer); (3) KWK electricity - Identification and evaluation (Matthias Krause); (4) Investigation of the storage ability of district heating grids and implementation into the optimized planning of heat generators (Sebastian Gross); (5) Autarcic thermal densification to the combined heat and power and cooling production? - A fundamental thermodynamic consideration (Torben Moeller); (6) Modelling of cogeneration power plants - Investigation of the transformation opportunity of existing district heating systems in LowEx grids (Martin Rhein); (7) Discrete building model for the dynamic thermohydraulic simulation of district heating (Dominik Haas); (8) Ventilation and degasification of solar power plants (Karin Ruehling); (9) Integral simulation of district heating with TRNSYS-TUD (Steffen Robbi); (10) Theoretical analyses of return temperatures in building heating networks (Andreas Meinzenbach); (11) Municipal energy efficiency as an important contribution to the reduction of greenhouse gas emissions (Matthias Mischke); (12) Investigation of the latent heat storage system PK 6 for use in air-conditioning installations (Sebastian Pinnau); (13) The role of the thermodynamics in the electromobility (Lars Schinke); (14) Flow and heat transfer in cooling channels with methane (Andre Schlott); (15) Numerical calculations of stoves fired with wooden logs (Ulf Senechal); (16) Supply of thermodynamic substance data for working fluids of power engineering (Hans-Joachim Kretzschmar); (17) Cyclic pipe-ground interaction in solar-thermal heat grids

Entanglement Entropy in Quantum Spin Chains with Finite Range Interaction

Science.gov (United States)

Its, A. R.; Mezzadri, F.; Mo, M. Y.

2008-11-01

We study the entropy of entanglement of the ground state in a wide family of one-dimensional quantum spin chains whose interaction is of finite range and translation invariant. Such systems can be thought of as generalizations of the XY model. The chain is divided in two parts: one containing the first consecutive L spins; the second the remaining ones. In this setting the entropy of entanglement is the von Neumann entropy of either part. At the core of our computation is the explicit evaluation of the leading order term as L → ∞ of the determinant of a block-Toeplitz matrix with symbol Φ(z) = left(begin{array}{cc} iλ & g(z) \\ g^{-1}(z) & i λ right), where g( z) is the square root of a rational function and g(1/ z) = g -1( z). The asymptotics of such determinant is computed in terms of multi-dimensional theta-functions associated to a hyperelliptic curve {mathcal{L}} of genus g ≥ 1, which enter into the solution of a Riemann-Hilbert problem. Phase transitions for these systems are characterized by the branch points of {mathcal{L}} approaching the unit circle. In these circumstances the entropy diverges logarithmically. We also recover, as particular cases, the formulae for the entropy discovered by Jin and Korepin [14] for the XX model and Its, Jin and Korepin [12, 13] for the XY model.

Time-Domain Full-Wave Modeling of Nonlinear Air Breakdown in High-Power Microwave Devices and Systems

Science.gov (United States)

2017-09-30

distribution is unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT This final report describes the effort to develop a discontinuous Galerkin time ...Approved for public release; distribution is unlimited. 1.0 SUMMARY In this report, a discontinuous Galerkin time -domain (DGTD) method is developed...public release; distribution is unlimited. [23] S. Yan, C.-P. Lin, R. R. Arslanbekov, V. I. Kolobov, and J.-M. Jin, “A discontinuous Galerkin time

Treating Melanoma Metastases with a Novel Photodynamic Approach

Science.gov (United States)

2017-09-01

AWARD NUMBER: W81XWH-15-1-0270 TITLE: Treating Melanoma Metastases with a Novel Photodynamic Approach PRINCIPAL INVESTIGATOR: Jin Xie...Metastases with a Novel Photodynamic Approach 5a. CONTRACT NUMBER Treating Melanoma Metastases with a Novel Photodynamic Approach 5b. GRANT NUMBER...ligand and after systemic injection, home to tumors in the lung. X-ray of relatively low doses can then be applied externally to the lung area to

Latent class analysis on internet and smartphone addiction in college students

OpenAIRE

Mok, Jung-Yeon; Choi, Sam-Wook; Kim, Dai-Jin; Choi, Jung-Seok; Lee, Jaewon; Ahn, Heejune; Choi, Eun-Jeung; Song, Won-Young

2014-01-01

Jung-Yeon Mok,1 Sam-Wook Choi,1,2 Dai-Jin Kim,3 Jung-Seok Choi,4 Jaewon Lee,2 Heejune Ahn,5 Eun-Jeung Choi,6 Won-Young Song7 1Eulji Addiction Institute, Eulji University, Seoul, South Korea; 2Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, South Korea; 3Department of Psychiatry, Seoul St Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, South Korea; 4Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, South Korea; 5Depar...

Growth of solutions of an $n$-th order linear differential equation with entire coefficients

OpenAIRE

Bela\\"{i}di, Benharrat; Hamouda, Saada

2002-01-01

We consider a differential equation $f^{\\left( n\\right) }+A_{n-1}\\left( z\\right) f^{\\left( n-1\\right) }+...+A_{1}\\left( z\\right) f^{^{/}}+A_{0}\\left( z\\right) f=0,$ where $A_{0}\\left( z\\right) ,...,A_{n-1}\\left( z\\right) $ are entire functions with $A_{0}\\left( z\\right) \\hbox{$/\\hskip -11pt\\equiv$}0$. Suppose that there exist a positive number $\\mu ,$\\ and a sequence $\\left( z_{j}\\right) _{j\\in N}$ with $\\stackunder{j\\rightarrow +\\infty }{\\lim }z_{j}=\\infty ,$ \\ and also ...

Symposium KK: Structure-Property Relationships in Biomineralized and Bio-mimetic Composites

Science.gov (United States)

2010-04-06

Preventive and Restorative Dental Sciences, UCSF, San Francisco, California. 4:45 PM KK2.8 Damage and Crack Evolution in Mammalian Enamel James Jin...Technology, Graz, Austria. 9:45AMKK6.S AFM and PFM measurements of Enamel in order to Determine the Crack Tip Toughness and Cohesive Zone of Enamel Gerold...11:00 AM KK9.7 Enamel Matrix Guided Growth of Apatite Vuk Uskokovic1. Li Zhu2, Wu Li2 and Stefan Habelitz1; ’Department of Preventive and

N-Terminal Tau Fragments as Biomarkers for Alzheimer’s Disease and Neurotrauma

Science.gov (United States)

2014-10-01

from the Tau Front: Cantoblanco 2013 J Alzheimers Dis Parkinsonism 4, e133 3. Saman S, Lee N, Inoyo I, Jin J, Li Z, Doyle T, McKee AC, Hall GF...diseases, as mitochondrial markers are prominently associated with Parkinsons Disease (hsa05012) and Huntington’s Disease (hsa05016) as well as AD...connectivity in Figure 2b, the 1” boxes (shaded) were placed so as to maximize icon inclusion (black dots) for each 1.9” diagram shown. The

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence

Directory of Open Access Journals (Sweden)

R. Xu

2015-08-01

Full Text Available Chronic ethanol consumption can produce learning and memory deficits. Brain-derived neurotrophic factor (BDNF and its receptors affect the pathogenesis of alcoholism. In this study, we examined the expression of BDNF, tropomyosin receptor kinase B (TrkB and p75 neurotrophin receptor (p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence. Twenty domestic dogs (9-10 months old, 15-20 kg; 10 males and 10 females were obtained from Harbin Medical University. A stable alcoholism model was established through ad libitum feeding, and anti-alcohol drug treatment (Zhong Yao Jie Jiu Ling, the main ingredient was the stems of watermelon; developed in our laboratory, at low- and high-doses, was carried out. The Zhong Yao Jie Jiu Ling was effective for the alcoholism in dogs. The morphology of hippocampal neurons was evaluated using hematoxylin-eosin staining. The number and morphological features of BDNF, TrkB and p75NTR-positive neurons in the dentate gyrus (DG, and the CA1, CA3 and CA4 regions of the hippocampus were observed using immunohistochemistry. One-way ANOVA was used to determine differences in BDNF, TrkB and p75NTR expression. BDNF, TrkB and p75NTR-positive cells were mainly localized in the granular cell layer of the DG and in the pyramidal cell layer of the CA1, CA3 and CA4 regions (DG>CA1>CA3>CA4. Expression levels of both BDNF and TrkB were decreased in chronic alcoholism, and increased after abstinence. The CA4 region appeared to show the greatest differences. Changes in p75NTR expression were the opposite of those of BDNF and TrkB, with the greatest differences observed in the DG and CA4 regions.

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence

International Nuclear Information System (INIS)

Xu, R.; Duan, S.R.; Zhao, J.W.; Wang, C.Y.

2015-01-01

Chronic ethanol consumption can produce learning and memory deficits. Brain-derived neurotrophic factor (BDNF) and its receptors affect the pathogenesis of alcoholism. In this study, we examined the expression of BDNF, tropomyosin receptor kinase B (TrkB) and p75 neurotrophin receptor (p75NTR) in the hippocampus of a dog model of chronic alcoholism and abstinence. Twenty domestic dogs (9-10 months old, 15-20 kg; 10 males and 10 females) were obtained from Harbin Medical University. A stable alcoholism model was established through ad libitum feeding, and anti-alcohol drug treatment (Zhong Yao Jie Jiu Ling, the main ingredient was the stems of watermelon; developed in our laboratory), at low- and high-doses, was carried out. The Zhong Yao Jie Jiu Ling was effective for the alcoholism in dogs. The morphology of hippocampal neurons was evaluated using hematoxylin-eosin staining. The number and morphological features of BDNF, TrkB and p75NTR-positive neurons in the dentate gyrus (DG), and the CA1, CA3 and CA4 regions of the hippocampus were observed using immunohistochemistry. One-way ANOVA was used to determine differences in BDNF, TrkB and p75NTR expression. BDNF, TrkB and p75NTR-positive cells were mainly localized in the granular cell layer of the DG and in the pyramidal cell layer of the CA1, CA3 and CA4 regions (DG>CA1>CA3>CA4). Expression levels of both BDNF and TrkB were decreased in chronic alcoholism, and increased after abstinence. The CA4 region appeared to show the greatest differences. Changes in p75NTR expression were the opposite of those of BDNF and TrkB, with the greatest differences observed in the DG and CA4 regions

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence

Energy Technology Data Exchange (ETDEWEB)

Xu, R.; Duan, S.R.; Zhao, J.W.; Wang, C.Y. [Neurology Ward of Internal Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province (China)

2015-06-23

Chronic ethanol consumption can produce learning and memory deficits. Brain-derived neurotrophic factor (BDNF) and its receptors affect the pathogenesis of alcoholism. In this study, we examined the expression of BDNF, tropomyosin receptor kinase B (TrkB) and p75 neurotrophin receptor (p75NTR) in the hippocampus of a dog model of chronic alcoholism and abstinence. Twenty domestic dogs (9-10 months old, 15-20 kg; 10 males and 10 females) were obtained from Harbin Medical University. A stable alcoholism model was established through ad libitum feeding, and anti-alcohol drug treatment (Zhong Yao Jie Jiu Ling, the main ingredient was the stems of watermelon; developed in our laboratory), at low- and high-doses, was carried out. The Zhong Yao Jie Jiu Ling was effective for the alcoholism in dogs. The morphology of hippocampal neurons was evaluated using hematoxylin-eosin staining. The number and morphological features of BDNF, TrkB and p75NTR-positive neurons in the dentate gyrus (DG), and the CA1, CA3 and CA4 regions of the hippocampus were observed using immunohistochemistry. One-way ANOVA was used to determine differences in BDNF, TrkB and p75NTR expression. BDNF, TrkB and p75NTR-positive cells were mainly localized in the granular cell layer of the DG and in the pyramidal cell layer of the CA1, CA3 and CA4 regions (DG>CA1>CA3>CA4). Expression levels of both BDNF and TrkB were decreased in chronic alcoholism, and increased after abstinence. The CA4 region appeared to show the greatest differences. Changes in p75NTR expression were the opposite of those of BDNF and TrkB, with the greatest differences observed in the DG and CA4 regions.

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence.

Science.gov (United States)

Xu, R; Duan, S R; Zhao, J W; Wang, C Y

2015-08-01

Chronic ethanol consumption can produce learning and memory deficits. Brain-derived neurotrophic factor (BDNF) and its receptors affect the pathogenesis of alcoholism. In this study, we examined the expression of BDNF, tropomyosin receptor kinase B (TrkB) and p75 neurotrophin receptor (p75NTR) in the hippocampus of a dog model of chronic alcoholism and abstinence. Twenty domestic dogs (9-10 months old, 15-20 kg; 10 males and 10 females) were obtained from Harbin Medical University. A stable alcoholism model was established through ad libitum feeding, and anti-alcohol drug treatment (Zhong Yao Jie Jiu Ling, the main ingredient was the stems of watermelon; developed in our laboratory), at low- and high-doses, was carried out. The Zhong Yao Jie Jiu Ling was effective for the alcoholism in dogs. The morphology of hippocampal neurons was evaluated using hematoxylin-eosin staining. The number and morphological features of BDNF, TrkB and p75NTR-positive neurons in the dentate gyrus (DG), and the CA1, CA3 and CA4 regions of the hippocampus were observed using immunohistochemistry. One-way ANOVA was used to determine differences in BDNF, TrkB and p75NTR expression. BDNF, TrkB and p75NTR-positive cells were mainly localized in the granular cell layer of the DG and in the pyramidal cell layer of the CA1, CA3 and CA4 regions (DG>CA1>CA3>CA4). Expression levels of both BDNF and TrkB were decreased in chronic alcoholism, and increased after abstinence. The CA4 region appeared to show the greatest differences. Changes in p75NTR expression were the opposite of those of BDNF and TrkB, with the greatest differences observed in the DG and CA4 regions.

Advances in network complexity

CERN Document Server

Dehmer, Matthias; Emmert-Streib, Frank

2013-01-01

A well-balanced overview of mathematical approaches to describe complex systems, ranging from chemical reactions to gene regulation networks, from ecological systems to examples from social sciences. Matthias Dehmer and Abbe Mowshowitz, a well-known pioneer in the field, co-edit this volume and are careful to include not only classical but also non-classical approaches so as to ensure topicality. Overall, a valuable addition to the literature and a must-have for anyone dealing with complex systems.

Inhibition of microRNA-214-5p promotes cell survival and extracellular matrix formation by targeting collagen type IV alpha 1 in osteoblastic MC3T3-E1 cells.

Science.gov (United States)

Li, Q S; Meng, F Y; Zhao, Y H; Jin, C L; Tian, J; Yi, X J

2017-08-01

This study aimed to investigate the functional effects of microRNA (miR)-214-5p on osteoblastic cells, which might provide a potential role of miR-214-5p in bone fracture healing. Blood samples were obtained from patients with hand fracture or intra-articular calcaneal fracture and from healthy controls (HCs). Expression of miR-214-5p was monitored by qRT-PCR at day 7, 14 and 21 post-surgery. Mouse osteoblastic MC3T3-E1 cells were transfected with antisense oligonucleotides (ASO)-miR-214-5p, collagen type IV alpha 1 (COL4A1) vector or their controls; thereafter, cell viability, apoptotic rate, and the expression of collagen type I alpha 1 (COL1A1), type II collagen (COL-II), and type X collagen (COL-X) were determined. Luciferase reporter assay, qRT-PCR, and Western blot were performed to ascertain whether COL4A1 was a target of miR-214-5p. Plasma miR-214-5p was highly expressed in patients with bone fracture compared with HCs after fracture (p extracellular matrix (ECM) formation of osteoblastic MC3T3-E1 cells by targeting COL4A1. Cite this article: Q. S. Li, F. Y. Meng, Y. H. Zhao, C. L. Jin, J. Tian, X. J. Yi. Inhibition of microRNA-214-5p promotes cell survival and extracellular matrix formation by targeting collagen type IV alpha 1 in osteoblastic MC3T3-E1 cells. Bone Joint Res 2017;6:464-471. DOI: 10.1302/2046-3758.68.BJR-2016-0208.R2. © 2017 Yi et al.

Expression profiles of a MhCTR1 gene in relation to banana fruit ripening.

Science.gov (United States)

Hu, Huei-Lin; Do, Yi-Yin; Huang, Pung-Ling

2012-07-01

The banana (Musa spp.) is a typical climacteric fruit of high economic importance. The development of bananas from maturing to ripening is characterized by increased ethylene production accompanied by a respiration burst. To elucidate the signal transduction pathway involved in the ethylene regulation of banana ripening, a gene homologous to Arabidopsis CTR1 (constitutive triple response 1) was isolated from Musa spp. (Hsien Jin Chiao, AAA group) and designated as MhCTR1. MhCTR1 spans 11.5 kilobases and consists of 15 exons and 14 introns with consensus GT-AG nucleotides situated at their boundaries. MhCTR1 encodes a polypeptide of 805 amino acid residues with a calculated molecular weight of 88.6 kDa. The deduced amino acid sequence of MhCTR1 demonstrates 55%, 56% and 55% homology to AtCTR1, RhCTR1, and LeCTR1, respectively. MhCTR1 is expressed mostly in the mature green pulp and root organs. During fruit development MhCTR1 expression increases just before ethylene production rises. Moreover, MhCTR1 expression was detected mainly in the pulps at ripening stage 3, and correlated with the onset of peel yellowing, while MhCTR1 was constitutively expressed in the peels. MhCTR1 expression could be induced by ethylene treatment (0.01 μL L(-1)), and MhCTR1 expression decreased in both peel and pulp 24 h after treatment. Overall, changes observed in MhCTR1 expression in the pulp closely related to the regulation of the banana ripening process. Copyright © 2012. Published by Elsevier Masson SAS.

POLITIK PEMBERLAKUAN SYARI`AT ISLAM DI ACEH DAN KELANTAN (1993-2014

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Khamami Zada

2015-06-01

Full Text Available The application of Islamic rules in Aceh and Kelantan is also related to the political power. There is a significant difference about political treatment on the application of Islamic law in Aceh and Kelantan. In Aceh, the central government (Indonesia thinks that it is needed to apply jinâyah law in Aceh as a strategy to solve conflicts. This political rule has been applied in the republic of Indonesia since the leadership of Habibie, Abdurrahman Wahid, Megawati Soekarno Putri to Susilo Bambang Yudhoyono. The main factor that influences the Indonesian political government rule is the central conflict with the Acehnese in the leadership of Soeharto presidential to the Helsinski Agreement 2005. Some vertical conflicts happened between the central government and the Acehnese were solved by giving special autonomy in applying the Islamic rules. Not only family law and economic law which are given autonomy to be applied in Aceh, but also the autonomy to apply jinâyah Law. In Kelantan, Federal government (Malaysia did not have political wish to apply Jinayah Law in Kelantan since the leadership of Mahathir Muhammad, Abdullah Badawi to Najib Razak. Moreover the federal government made the issue of the application of jinâyah law as the political commodity to get the political sympathy from the people, who are the partner of non Moslem voters in the national ranks and some Moslem voters who are not affiliated with PAS. This political needs factor is kept by the Federal Government to respond the Kelantan’s government wish to apply Islamic rules.Copyright (c 2015 by Al-Ihkam. All right reserved DOI : 10.19105/al-ihkam.v10i1.588 

Chinese-English Rocketry Dictionary. Volume 3

Science.gov (United States)

1979-03-01

holder; mount ; brace; am; outri•gger ZhiJu substation ; out station; 11 subcontrol office; suboffice; out office; minor office zhikeceng subehell 12... pad 09 tarthuang’e JrI• M’ spring yoke LU tanhuanggang Vr 4i spring steel 11 Lanhuanggang huomen •T• . S (. P•i sprign-s ,eel shutter 12 tanhuanggong...lead; teadin’. tiqi-an 15,2.am f41 ýi IV1 prnrratin’e detmnation ɞ tiqjita --edJin;1, siijian, 41 i Al ] Jillmdern intLerval tipo -n 6113.r1u 41Ff

Journal of EEA, Vol. 25, 2008

African Journals Online (AJOL)

FACE RECOGNITION USING ARTIFICIAL NEURAL NETWORK. Sentayehu Endeshaw and .... Number of statistical and Artificial Intelligence techniques have been ..... college publishing company, Newyork, 1994. [4] Hyun Jin Park and Hyun ...

Soo soomlaste südames ja soo lugudes / Piret Paal

Index Scriptorium Estoniae

Paal, Piret, 1977-

2011-01-01

Tutvustus: Laurén, Kirsi. Suo - sisulla ja sydämellä : suomalaisten suokokemukset ja -kertomukset kulttuurisen luontosuhteen ilmentäjinä. Helsinki : Suomalaisen Kirjallisuuden Seura, 2006 (doktoritöö)

Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia

OpenAIRE

Cheng, Minfeng; Gu, Huaying; Zheng, Liangrong; Wang, Houliang; Zhong, Zhiyong; Wen, Shenglin

2016-01-01

Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt ...

Interferons and their potential in the treatment of ocular inflammation

Directory of Open Access Journals (Sweden)

Friederike Mackensen

2009-10-01

Full Text Available Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Zürich, SwitzerlandAbstract: Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice.Keywords: interferon, uveitis, treatment, inflammation

Bright Two-Photon Emission and Ultra-Fast Relaxation Dynamics in a DNA-Templated Nanocluster Investigated by Ultra-Fast Spectroscopy

Science.gov (United States)

2012-01-01

Research Office (Materials program) and the National Science Foundation ( Polymer program) for support of this work. Reference (1) Mie, G. Beiträge...Quantum Effects in Optical Spectra. The Journal of Physical Chemistry B 1997, 101, 7885–7891. (6) Jin, R. Quantum sized, thiolate -protected gold...Physics Letters 1997, 266, 91–98. (13) Ackerson, C. J.; Jadzinsky, P. D.; Kornberg, R. D. Thiolate ligands for synthesis of water-soluble gold clusters

Global Existence of Classical Solutions to the Equations of Motion for Materials with Fading Memory.

Science.gov (United States)

1984-02-01

influence function , history value problems, classical solutions, global existence, decay. Work Unit Number 1 - Applied Analysis Sponsored by the United...introduce an " influence function " h, intended to JIN. characterize the rate at which memory fades, and construct an LP-type space of admissible...histories using the influence function as a weight. Here we use the term influence function to mean a positive, nonincreasing, real-valued function h e L (0

Detection of Heart Sounds in Children with and without Pulmonary Arterial Hypertension--Daubechies Wavelets Approach.

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Mohamed Elgendi

Full Text Available Automatic detection of the 1st (S1 and 2nd (S2 heart sounds is difficult, and existing algorithms are imprecise. We sought to develop a wavelet-based algorithm for the detection of S1 and S2 in children with and without pulmonary arterial hypertension (PAH.Heart sounds were recorded at the second left intercostal space and the cardiac apex with a digital stethoscope simultaneously with pulmonary arterial pressure (PAP. We developed a Daubechies wavelet algorithm for the automatic detection of S1 and S2 using the wavelet coefficient 'D6' based on power spectral analysis. We compared our algorithm with four other Daubechies wavelet-based algorithms published by Liang, Kumar, Wang, and Zhong. We annotated S1 and S2 from an audiovisual examination of the phonocardiographic tracing by two trained cardiologists and the observation that in all subjects systole was shorter than diastole.We studied 22 subjects (9 males and 13 females, median age 6 years, range 0.25-19. Eleven subjects had a mean PAP < 25 mmHg. Eleven subjects had PAH with a mean PAP ≥ 25 mmHg. All subjects had a pulmonary artery wedge pressure ≤ 15 mmHg. The sensitivity (SE and positive predictivity (+P of our algorithm were 70% and 68%, respectively. In comparison, the SE and +P of Liang were 59% and 42%, Kumar 19% and 12%, Wang 50% and 45%, and Zhong 43% and 53%, respectively. Our algorithm demonstrated robustness and outperformed the other methods up to a signal-to-noise ratio (SNR of 10 dB. For all algorithms, detection errors arose from low-amplitude peaks, fast heart rates, low signal-to-noise ratio, and fixed thresholds.Our algorithm for the detection of S1 and S2 improves the performance of existing Daubechies-based algorithms and justifies the use of the wavelet coefficient 'D6' through power spectral analysis. Also, the robustness despite ambient noise may improve real world clinical performance.

Systematic Search for Gene-Gene Interaction Effect on Prostate Cancer Risk

Science.gov (United States)

2013-07-01

Systematic Search for Gene-Gene Interaction 5a. CONTRACT NUMBER Effect on Prostate Cancer Risk 5b. GRANT NUMBER W81XWH-09-1-0488 5c. PROGRAM...Supported by this grant ) 1. Tao S, Wang Z, Feng J, Hsu FC, Jin G, Kin ST, Zhang Z, Gronberg H, Zheng, SL, Isaacs WB, XU J, Sun J. A Genome-Wide Search for...order interactions among estrogen- metabolism genes in sporadic breast cancer. Am J Hum Genet, 69, 138-47. 48. Marchini, J., Donnelly, P. and Cardon

Historik jiné moderny: Té horší

Czech Academy of Sciences Publication Activity Database

Hlavačka, Milan

2017-01-01

Roč. 30, 24. 6. (2017), s. 22 ISSN 0862-5921 Institutional support: RVO:67985963 Keywords : Bedřich Loewenstein * historian * modern civilisation OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

Fresh insights | IDRC - International Development Research Centre

International Development Research Centre (IDRC) Digital Library (Canada)

2011-07-08

Jul 8, 2011 ... ... the effectiveness of price subsidies in reducing the financial burden of health ... reimbursing in-patient costs (Feng Jin, Fudan University, Shanghai). ... Community solidarity helps to solve environmental and health problems.

Lung cancer with concurrent EGFR mutation and ROS1 rearrangement: a case report and review of the literature

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Zhu YC

2016-07-01

Full Text Available You-cai Zhu,1,2,* Chun-wei Xu,3,* Xiao-qian Ye,4 Man-xiang Yin,4 Jin-xian Zhang,2 Kai-qi Du,2 Zhi-hao Zhang,2 Jian Hu1 1Department of Thoracic Surgery, The First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou, 2Department of Thoracic Surgery, Chinese People’s Armed Police Force, Zhejiang Corps Hospital, Jiaxing, Zhejiang, 3Department of Pathology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 4Department of Pathology, Chinese People’s Armed Police Force, Zhejiang Corps Hospital, Jiaxing, Zhejiang, People’s Republic of China *These authors contributed equally to this work Abstract: ROS1 rearrangement has recently emerged as a new molecular subtype in non-small cell lung cancer, and is predominantly found in lung adenocarcinomas compared with other oncogenes such as EGFR, KRAS, or ALK. Patients who have both mutations are extremely rare. Here we report a 50-year-old female diagnosed with adenocarcinoma with sarcomatoid differentiation, who was shown to have EGFR and ROS1 mutations. The patient was treated surgically and received three cycles of adjuvant postoperative chemotherapy. In addition, we reviewed the previously reported cases and related literature. This presentation will provide further understanding of the underlying molecular biology and optimal treatment for non-small cell lung cancer patients with more than one driver mutation. Keywords: non-small cell lung cancer, EGFR gene mutation, ROS1 fusion gene

„Čelakovský - ausserordentlich ruhig“. Otázka generací a loajalit v české politice

Czech Academy of Sciences Publication Activity Database

Pavlíček, Tomáš W.

2015-01-01

Roč. 45, č. 1 (2015), s. 127-137 ISSN 0079-4929. [Formování vědního oboru národních právních dějin ve střední Evropě. Pocta prof. Jaromíru Čelakovskému (1846–1914). Praha, 04.11.2014-06.11.2014] Institutional support: RVO:67985921 Keywords : Čelakovský, Jaromír * political culture Subject RIV: AB - History

Muusikauudiseid maailmast / Nele-Eva Steinfeld

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2015-01-01

Lühisõnumeid maailmast: Chopini-nimelise konkursi Varssavis võitis Seong-Jin Cho. Martha Argerichile mitu auhinda. Tšaikovski konkursi laureaat Lucas Debargue Sony ja CAMi artist. Augustin Hadelich võitis Warneri preemia jne.

Classification of single travelling wave solutions to the generalized ...

Indian Academy of Sciences (India)

Kuznetsov equation. JIN-YAN HU. Department of Mathematics, Northeast Petroleum University, Daqing 163318, China. E-mail: hujinyan_Alice@163.com; 13836955068@163.com. MS received 20 May 2012; revised 6 December 2012; accepted ...

Větrná energetika a střety s jinými technologiemi

Czech Academy of Sciences Publication Activity Database

Hanslian, David

2009-01-01

Roč. 3, č. 1 (2009), s. 12-13 ISSN 1802-8535 Institutional research plan: CEZ:AV0Z30420517 Keywords : wind energy * wind energy potential * technical limits of wind energy Subject RIV: JE - Non-nuclear Energetics, Energy Consumption ; Use

Comparison of clinical outcomes in PRK with a standard and aspherical optimized profile: a full case analysis of 100 eyes with 1-year follow-up

Directory of Open Access Journals (Sweden)

Dausch D

2014-11-01

Full Text Available Dieter Dausch,1,2 Burglinde Dausch,2 Matthias Wottke,3 Georg Sluyterman van Langeweyde31Chung-Ang University, Seoul, South Korea; 2Augen-Laser-Klinik Nürnberg, Nuremberg, Germany; 3Carl Zeiss Meditec AG, Jena, Germany Purpose: One hundred eyes from 55 adult patients with myopia were retrospectively studied to determine the comparative safety, efficacy, and predictability of aberration smart ablation (ASA and a new advanced ablation algorithm (Triple-A using the MEL® 80 excimer laser.Methods: Fifty myopic eyes with a manifest refraction spherical equivalent (MRSE between -1.0 diopters (D and -9.75 D were consecutively treated with photorefractive keratectomy ASA, and 50 myopic eyes with an MRSE between -1.38 D and -11.0 D with photorefractive keratectomy Triple-A. Uncorrected distance visual acuity, MRSE, the absolute value of the cylinder, corrected distance visual acuity, and postoperative complications at 1 month, 3 months, 6 months, and 12 months (1 year were descriptively analyzed and compared at 1 year.Results: After 12 months, the MRSE variance was statistically significantly better in patients triaged to receive Triple-A compared with patients receiving ASA (ASA, ±0.7 D; Triple-A, ±0.15 D; P<0.001. Furthermore, no patient in the Triple-A group had any cylinder postoperatively. Patients in the Triple-A treatment arm achieved a superior result. No statistically significant difference in the two treatment arms was noted for the analysis of the mean MRSE at 12 months (P=0.78.Conclusion: Triple-A was more effective than standard aspherical surgical intervention in a number of treatment outcome parameters (eg, MRSE, astigmatism, efficacy index. The two surgical procedures were equivalent in terms of safety. Keywords: aberration smart ablation (ASA, manifest refraction spherical equivalent, Triple-A advanced ablation algorithm, uncorrected distance visual acuity, corrected distance visual acuity, excimer laser, PRK, ablation profile

Bibliografía

OpenAIRE

2015-01-01

Abram, Matthias1992. Lengua, cultura e identidad. El proyecto EBl 1985-1990. Quito: Proyecto EBI/Abya Yala. Academia Mayor de la Lengua Quechua1995 Diccionario Quechua-Español-Quechua. Qheswa-Español-Qheswa Simi Taqe. Cuzco: Municipalidad del Cuzco. Adelaar, Willem1977. Tarma Quechua. Grammar, Texts, Dictionary. Lisse: Peter de Ridder Press.1986 “La relación quechua-aru: perspectivas para la separación del léxico”. Revista Andina 4 (2): 379426.1999. “Unprotected Languages: The Silent Death of...

Jin and Min Afr J Tradit Complement Altern Med. (2013) 10(3):508 ...

African Journals Online (AJOL)

AJTCAM

reasons make elderly patients prone to ADR (Xie et al., 2004): (1) With age increases, the organs in the elderly degrade year. Table 4: Drug varieties causing ADR .... to drug administration methods and compatibility: to minimize the proportion of intravenous administration and combination of many drugs. (3) Strengthen the ...

Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

Index Scriptorium Estoniae

Kim Sung Hong

2009-01-01

Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Science.gov (United States)

2012-07-27

... JACINTA YEUNG CHEONG CHANG MICHAEL YIO-HOW CHENG NICOLAS VINCENT CHI TELLY TAI HSUAN CHINOY SAMIR MUSTAPHA... TONJA YVONNE SU JIN CHIN SU XIAOBO SARA SHAO SUEN SAMSON C. L. SY KEVIN NEIL TAN LAI HING THARALDSEN...

All Prime Contract Awards by State or Country, Place and Contractor. Part 7. (Aiea, Hawaii-Zion, Illinois)

Science.gov (United States)

1989-01-01

L1J M 1 C- gao 0 0000 00 0 00000000 C 0 0 3 0 0011 I III.,,~ , :1 W N In I 2 2 I W-4 IIzzz 2 z22Z2Z22 2 ZZ2 2 2 Z C. QI 00 IImm m innnniiii co innnii...ig1.0 I ca -4 of z00 ZNIC𔃻 0)CM r-Nr 4N 4(D 0(0 c(00) 00 00 .tol~031 01 so1400 00)0 44-4 -40C 3(c jinI 47U)) w Nl -.1.> ILALA 4on flII-I(-4 11I1100 00-4

Protecting Networks Via Automated Defense of Cyber Systems

Science.gov (United States)

2016-09-01

gray-hats/. 61 Hu, Youfan, Yan Zhang, Chen Xu, Long Lin, Robert L. Snyder, and Zhong Lin Wang. “Self-Powered System with Wireless Data Transmission ...wires will almost completely cease to exist, replaced by mobile nanodevices, which are tiny computers measured in nanometers with integrated wireless ... energy companies, was hypothesized to cost $10,000. Raiu went on to opine, “The cost of entry for [advanced persistent threats] is decreasing …. We’re

Prof. Jaromír Čelakovský a Národní strana svobodomyslná zv. mladočeská

Czech Academy of Sciences Publication Activity Database

Velek, Luboš

2015-01-01

Roč. 45, č. 1 (2015), s. 112-126 ISSN 0079-4929. [Formování vědního oboru národních právních dějin ve střední Evropě. Pocta prof. Jaromíru Čelakovskému (1846–1914). Praha, 04.11.2014-06.11.2014] Institutional support: RVO:67985921 Keywords : Čelakovský, Jaromír * National Liberal Party (the Young Czechs) Subject RIV: AB - History

Znamenitá zpráva se nese věčně dál. Nekrolog císařovny Yang a život císařovny v zrcadle středověkých pramenů

Czech Academy of Sciences Publication Activity Database

Hrubý, Jakub

2011-01-01

Roč. 2, - (2011), 47-72. ISBN 978-80-246-2029-9. ISSN 0474-6635 Institutional research plan: CEZ:AV0Z90210515 Keywords : Medieval China * Western Jin Dynasty * Empress Yang * historiography * Zuo Fen Subject RIV: AB - History

Speaker-dependent Multipitch Tracking Using Deep Neural Networks

Science.gov (United States)

2015-01-01

sentences spoken by each of 34 speakers (18 male, 16 female). Two male and two female speakers (No. 1, 2, 18, 20, same as [30]), denoted as MA1, MA2 ...Engineering Technical Report #12, 2015 Speaker Pairs MA1- MA2 MA1-FE1 MA1-FE2 MA2 -FE1 MA2 -FE2 FE1-FE2 E T ot al 0 10 20 30 40 50 60 70 80 Jin and Wang Hu and...Pitch 1 Estimated Pitch 2 (d) Figure 6: Multipitch tracking results on a test mixture (pbbv6n and priv3n) for the MA1- MA2 speaker pair. (a) Groundtruth

Radiology examination as a diagnostic aid in presentations with ...

African Journals Online (AJOL)

Radiology examination as a diagnostic aid in presentations with wide differential diagnoses: Case report of new Hodgkin's lymphoma on a background of poorly controlled HIV. Rachel Hubbard, Jalpa Kotecha, Thomas Nash, Yu Jin Lee, Nasir Khan, Farhat Kazmi ...

Indexes to Volume 67

Indian Academy of Sciences (India)

Exact solutions to a class of nonlinear Schrödinger-type equations. Jin-Liang Zhang .... Determination of thorium and uranium contents in soil samples using. SSNTD's ... Direct determination of bulk etching rate for LR-115-II solid state nuclear.

Holocene climate change in North Africa and the end of the African humid period - results of new high-resolution transient simulations with the MPI-ESM 1.3

Science.gov (United States)

Dallmeyer, Anne; Claussen, Martin; Lorenz, Stephan

2017-04-01

The Max-Planck-Institute for Meteorology has recently undertaken high-resolution transient Holocene simulations using the fully-coupled Earth System Model MPI-ESM 1.3. The simulations cover the last 8000 years and are forced not only by reconstructed Holocene orbital variations and atmospheric greenhouse gas concentrations, but also by recent compilations of Holocene volcanic aerosol distributions, variations in spectral solar irradiance, stratospheric ozone and land-use change. The simulations reveal the ubiquitous "Holocene conundrum": simulated global mean temperatures increase during the mid-Holocene and stay constant during the late Holocene. Simulated mid-Holocene near-surface temperatures are too cold in large parts of the world. Simulated precipitation, however, agrees much better with reconstruction than temperatures do. Likewise simulated global biome pattern fit reconstructions nicely, except for North Western America. First results of these simulations are presented with the main focus on the North African monsoon region. The amplitude of the mid-Holocene African Humid Period (AHP) is well captured in terms of precipitation and vegetation cover, so is the south-ward transgression of the termination of the AHP seen in reconstructions. The Holocene weakening and southward retreat of the North African monsoon as well as changes in the monsoon dynamic including shifts in the seasonal cycle and their relation to the locally varying termination of the AHP are discussed in detail. Members of the Hamburg Holocene Team: Jürgen Bader (1), Sebastian Bathiany (2), Victor Brovkin (1), Martin Claussen (1,3), Traute Crüger (1), Roberta D'agostino (1), Anne Dallmeyer (1), Sabine Egerer (1), Vivienne Groner (1), Matthias Heinze (1), Tatiana Ilyina (1), Johann Jungclaus (1), Thomas Kleinen (1), Alexander Lemburg (1), Stephan Lorenz (1), Thomas Raddatz (1), Hauke Schmidt (1), Gerhard Schmiedl (3), Bjorn Stevens (1), Claudia Timmreck (1), Matthew Toohey (4) (1) Max

ESTUDIO DEL EFECTO DE LA CRANEOACUPUNTURA EN PACIENTES CON ENFERMEDAD VASCULAR CEREBRAL. (EVC)

OpenAIRE

PEREZ BRAVO, MIGUEL

2009-01-01

LA ENFERMEDAD VASCULAR CEREBRAL (EVC) EN MEXICO ES UN IMPORTANTE PROBLEMA DE SALUD PUBLICA, ES LA TERCERA CAUSA DE MUERTE Y LA SEGUNDA EN PRODUCIR INCAPACIDAD NEUROLOGICA. EL OBJETIVO DE ESTE ESTUDIO FUE EVALUAR EL EFECTO DE LA CRANEOACUPUNTURA EN PACIENTES CON ENFERMEDAD VASCULAR CEREBRAL (ZHONG FENG). EL PRESENTE ES UN ESTUDIO EXPERIMENTAL, PROSPECTIVO Y LONGITUDINAL, REALIZADO EN EL HOSPITAL DEL ISSSTE DE LA CIUDAD DE PUEBLA, A UN GRUPO DE 11 PACIENTES DE AMBOS SEXOS, CON...

The People’s Liberation Army and China in Transition

Science.gov (United States)

2003-08-01

Chinese only. See “ Zhong - shan Daxue Diaocha Xianshi: Qi Cheng Xuetong Ji Ju Zhengdang Pian Hao” (“Sun Yat-sen University Poll shows 70 percent of...uneventfully to seats of power in Beijing . Hu became both state president and CCP general secretary. Yet the third generation of leaders, led by...geostrategic claims along China’s periphery. ■ Even as the war on terrorism has created a new context in which Washington and Beijing could begin

Geochemical and Rheological Constraints on the Dynamics of the Oceanic Upper Mantle

Science.gov (United States)

2007-09-01

this past year and I hope it continues for years to come. I thank my parents, Margaret and Colin , who have supported me in whatever I have 6 endeavored...et al., 1990; Drury et al., 1991; Jaroslow et al., 1996; Jin et al., 1998; Newman et al., 1999; Jiang et al., 2000). For the sample in Fig. 2. 1...plagioclase with decreasing pressure (e.g., Furusho and Kyuichi, 1999; Newman et al., 1999); see Drury et al. (1991 ) for a review of earlier literature

African Journal of Biotechnology - Vol 10, No 73 (2011)

African Journals Online (AJOL)

Morphological diversity of wild medicinal Paris L. from China and Vietnam · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JY Zhang, J Zhang, WZ Yang, YZ Wang, H Yu, H Jin, 16421-16428 ...

African Journal of Biotechnology - Vol 10, No 65 (2011)

African Journals Online (AJOL)

HQ Lou, Y Hu, L Zhang, YJ Zhang, PG Tu, XT Yu, YJ Jin, L Wang, 14286-14292 ... The effect of osmopriming on germination, seedling growth and phosphatase activities of lettuce under saline ... S Han, TH Zhu, SJ Li, FL Li, 14404-14409.

Treating Simple Tibia Fractures with Poly-DL-Lactic Acid Screw as a ...

African Journals Online (AJOL)

) absorbable screw as a ... fractures. Keywords: Simple tibia fracture, Fracture healing time Poly-DL-lactic acid, Poly-DL-Lactic Acid, ..... bilateral cortex of the bone due to the weak anti- ... Hu YL, Yuan WQ, Wang LF, Liu HF, Jin D. A prospective.

Festivalnõje vstretshi / Eteri Kekelidze

Index Scriptorium Estoniae

Kekelidze, Eteri, 1944-

2003-01-01

PÖFFi külalistest - vene režissööri Lidia Bobrova mängufilmi "Memmeke" operaator Valeri Revitsh ja neli külalist Hiinast, kelle seas festivalile toodud filmi "Krüsanteemitee" režissöör Jin Chen

Use of silane coupling agent for surface modification of zinc oxide as ...

Indian Academy of Sciences (India)

VI group of semiconductor having wurtzite structure and a direct wide bandgap of 3·37 ... et al 2007) and antibacterial activity (Zhang et al 2007; Jin et al 2009). ..... functionalized ZnO showed a fine dispersion in polymeric matrix. TGA results ...

Althusser, Marx a neempiristická teorie dějin

Czech Academy of Sciences Publication Activity Database

Kužel, Petr

2013-01-01

Roč. 10, č. 2 (2013), s. 191-208 ISSN 1214-7249 Institutional support: RVO:67985955 Keywords : empiricism * historical epistemology * Louis Althusser * Karl Marx Subject RIV: AA - Philosophy ; Religion http://www.dejinyteoriekritika.cz/Modules/ViewDocument.aspx?Did=410

αvβ3 integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo

Directory of Open Access Journals (Sweden)

Zhong P

2017-10-01

Full Text Available Ping Zhong,1,2 Xiaolei Gu,1,2 Ru Cheng,1,2 Chao Deng,1,2 Fenghua Meng,1,2 Zhiyuan Zhong1,2 1Biomedical Polymers Laboratory, 2Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, China Abstract: Antibody-mertansine (DM1 conjugates (AMCs are among the very few active targeting therapeutics that are approved or clinically investigated for treating various cancers including metastatic breast cancer. However, none of the AMCs are effective for the treatment of triple-negative breast cancers (TNBCs. Here, we show that cRGD-decorated, redox-activatable micellar mertansine prodrug (cRGD-MMP can effectively target and deliver DM1 to αvβ3 integrin overexpressing MDA-MB-231 TNBC xenografts in nude mice, resulting in potent tumor growth inhibition. 3-(4,5-Dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assays showed that cRGD-MMP had obvious targetability to MDA-MB-231 cells with a low half-maximal inhibitory concentration (IC50 of 0.18 µM, which was close to that of free DM1 and 2.2-fold lower than that of micellar mertansine prodrug (MMP; nontargeting control. The confocal microscopy studies demonstrated that cRGD-MMP mediated a clearly more efficient cellular uptake and intracellular release of doxorubicin (used as a fluorescent anticancer drug model in MDA-MB-231 cells. Notably, cRGD-MMP loaded with 1,1'-dioctadecyltetramethyl indotricarbocyanine iodide (DiR; a hydrophobic near-infrared dye was shown to quickly accumulate in the MDA-MB-231 tumor with strong DiR fluorescence from 2 to 24 h post injection. MMP loaded with DiR could also accumulate in the tumor, although significantly less than cRGD-MMP. The biodistribution studies revealed a high DM1 accumulation of 8.1%ID/g in the tumor for cRGD-MMP at 12 h post injection. The therapeutic results demonstrated that cRGD-MMP effectively suppressed MDA-MB-231 tumor growth at

A Research on Strategic Ambidexterity from the Perspective of Upper Echelons Theory%基于高阶理论视角的战略双元研究

Institute of Scientific and Technical Information of China (English)

王艺霖; 王益民

2015-01-01

文章以高阶理论和资源依赖理论为基础，探讨了制度转型期中国企业高管团队行为整合、政治联系、中庸思维与战略双元之间的关系。通过问卷调查的方式进行实证研究，研究结果表明，高管团队行为整合、高管团队政治联系对战略双元有正向影响。高管团队中庸思维弱化了高管团队行为整合与战略双元之间的关系。%Based on upper echelons theory and resource dependence theory,the paper examines the relationship between top management team behavioral integration,political connection,Zhong-yong thinking and strategic ambidexterity in Chinese enterprises during the process of institutional transition. The paper also makes an empirical study through questionnaire sur⁃vey. The findings show that both top management team behavioral integration and top management team political connection have positive relationships with strategic ambidexterity. Furthermore, top management team Zhong-yong thinking weakens the relationship between top management team behavioral integration and strategic ambidexterity.

[Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

Science.gov (United States)

Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

2014-01-01

Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

Conversations with Leaders: Principles of Effective Writing Instruction

Science.gov (United States)

Zumbrunn, Sharon; Krause, Keegan

2012-01-01

Findings from research demonstrate that student writing proficiency and classroom writing instruction is a national concern (Applebee & Langer, 2006, 2009; Graham, Harris, Fink-Chorzempa, & MacArthur, 2003; Persky, Daane, & Jin, 2003). This qualitative study explored principles of effective writing instruction through the perspectives of leading…

Fulltext PDF

Indian Academy of Sciences (India)

Unknown

of petroleum refineries and petrochemical industries. (Mancy and Weber 1971). Separation of phenol from industrial waste stream has gathered significant interest over past few decades (Krishnakumar and Sharma 1984). Some important methods regarding recovery of phenols include solvent extraction (Ge and Jin 1996), ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Three duplication events and variable molecular evolution characteristics involved in multiple GGPS genes of six Solanaceae species. FENG LI CHUNYANG WEI CHAN QIAO ZHENXI CHEN PENG WANG PAN WEI RAN WANG LIFENG JIN JUN YANG FUCHENG LIN ZHAOPENG LUO. RESEARCH NOTE Volume 95 Issue ...

The Optimal Portfolio Selection Model under g-Expectation

Directory of Open Access Journals (Sweden)

Li Li

2014-01-01

complicated and sophisticated, the optimal solution turns out to be surprisingly simple, the payoff of a portfolio of two binary claims. Also I give the economic meaning of my model and the comparison with that one in the work of Jin and Zhou, 2008.

76 FR 56397 - Small Diameter Graphite Electrodes from the People's Republic of China: Final Results of the...

Science.gov (United States)

2011-09-13

...-Specific Surrogate Wage Rates and Surrogate Financial Ratio Adjustments,'' dated June 29, 2011 (``Wage Rate... China: Analysis of the Final Results Margin Calculation for Fushun Jinly Petrochemical Carbon Co., Ltd... Analysis Memorandum. Changes to the Fangda Group's Margin Calculation We are excluding certain sales...

Manumycin from a new Streptomyces strain shows antagonistic ...

African Journals Online (AJOL)

Manumycin from a new Streptomyces strain shows antagonistic effect against methicillin-resistant Staphylococcus aureus (MRSA)/vancomycin-resistant enterococci (VRE) strains from Korean Hospitals. Yun Hee Choi, Seung Sik Cho, Jaya Ram Simkhada, Chi Nam Seong, Hyo Jeong Lee, Hong Seop Moon, Jin Cheol Yoo ...

DsRed gene expression by doxycycline in porcine fibroblasts and ...

African Journals Online (AJOL)

DsRed gene expression by doxycycline in porcine fibroblasts and cloned embryos using transposon. SuJin Kim, JoonHo Moon, BegoRoibas da Torre, Islam M Saadeldin, JungTaek Kang, JiYei Choi, SolJi Park, Byeong-Chun Lee, Goo Jang Goo Jang ...

An Exploration on Motivation of Non-English Majors in Polytechnics

Institute of Scientific and Technical Information of China (English)

赵庆伟

2016-01-01

This study, undertaken 100 students majoring in electronics in a polytechnic in TianJin, examines the characteristics of learning motivations in students: intrinsic and extrinsic motivation. Analysis of data acquired from a questionnaire suggests that the majority of polytechnic students are driven by extrinsic motivation.

Browse Title Index

African Journals Online (AJOL)

Items 401 - 450 of 1178 ... Y-X Zhou, J Chen, J-P Li, Y-L Wang, X-D Jin ... Vol 4, No 3 (2007), Comparative Chemical And Analgesic Properties Of Essential Oils ... Pilar Carranza-Rosales, Omar Heredia-Rodríguez, Gerardo Lozano-Garza, Angel ...

Structural characteristics of titanium coating on copper substrates

Indian Academy of Sciences (India)

Oya and Kusano 2009; Zhang et al 2009) and glass (Jin et al 2009; Oya and Kusano ... The objective of this work is to investigate the structure and interface of ..... nucleates and grows such that, a number of fine sized Ti crys- tallites appear ...

Nicholas Gilroy | NREL

Science.gov (United States)

Nicholas Gilroy desc Nicholas Gilroy Geospatial Data Scientist II Nicholas.Gilroy@nrel.gov | 303 -384-7354 Nicholas Gilroy is a member of the Geospatial Data Science team within the Systems Modeling (AAG) Featured Publications Veda, Santosh, Zhang, Yingchen, Tan, Jin, Chartan, Erol Kevin, Gilroy

Brain and Plasma Molecular Characterization of the Pathogenic TBI-AD Interrelationship in Mouse Models

Science.gov (United States)

2015-10-01

encephalopathy in the elderly: clinical expression and structural substrates. Neuropathol Appl Neurobiol 37, 570 -584. Crawford, F., Crynen, G., Reed, J...Beaulieu-Abdelahad, D., Lin, Y., Jin, C., Crawford, F., and Mullan, M. (2014). The Spleen Tyrosine Kinase (syk) Regulates Alzheimer’s Aβ

Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients

Directory of Open Access Journals (Sweden)

Park HY

2015-12-01

Full Text Available Hye Yun Park,1 Hyun Lee,1 Won-Jung Koh,1 Seonwoo Kim,2 Ina Jeong,3 Hyeon-Kyoung Koo,4 Tae-Hyung Kim,5 Jin Woo Kim,6 Woo Jin Kim,7 Yeon-Mok Oh,8 Don D Sin,9 Seong Yong Lim,10,* Sang-Do Lee8,* On behalf of the KOLD Study Group 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Biostatistics Team, Samsung Biomedical Research Institute, Seoul, Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center, Seoul, Korea; 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea; 5Division of Pulmonary and Critical Care Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Korea; 6Division of Pulmonology, Department of Internal Medicine, Uijeongbu St Mary’s Hospital, Gyunggi-do, Korea; 7Department of Internal Medicine, Kangwon National University, Chuncheon-si, Gangwon-do, Korea; 8Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 9Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada; 10Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea *These authors contributed equally to this work Background: COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS in combination with a long-acting bronchodilator. Recent studies have demonstrated a significant correlation of sputum eosinophilia with blood eosinophils and periostin. We investigated whether high blood eosinophils and plasma periostin were associated

ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization.

Science.gov (United States)

Li, Junjie; Xie, Jiangang; Liu, Shanshou; Li, Xiao; Zhang, Dongliang; Wang, Xianqi; Jiang, Jinquan; Hu, Wei; Zhang, Yuan; Jin, Boquan; Zhuang, Ran; Yin, Wen

2018-04-25

ADAR1 (adenosine deaminase acting on double-stranded RNA 1) is an RNA-editing enzyme that mediates adenosine-to-inosine RNA editing events, an important post-transcriptional modification mechanism that can alter the coding properties of mRNA or regulate microRNA biogenesis. ADAR1 also regulates the innate immune response. Here, we have demonstrated that ADAR1 expression increased in LPS-stimulated macrophages. Silencing ADAR1 by using small interfering RNA in macrophages resulted in the pronounced polarization of macrophages to M1, whereas ADAR1 overexpression promoted M2 polarization, which indicated that ADAR1 can inhibit macrophage hyperpolarization and prevent immune hyperactivity. The RNA-RNP immunoprecipitation binding assay demonstrated a direct interaction between ADAR1 and miR-21 precursor. Significant up-regulation in IL-10 and down-regulation in miR-21 were observed in ADAR1-overexpressing macrophages. We evaluated miR-21 target mRNAs and macrophage polarization signaling pathways and found that forkhead box protein O1 (Foxo1) was up-regulated in cells that overexpressed ADAR1. In a mouse allogeneic skin transplantation model, grafts in the ADAR1-overexpressed group survived longer and suffered less immune cell infiltration. In ADAR1-overexpressed recipients, splenic macrophages were significantly polarized to M2, and levels of sera IL-10 were markedly higher than those in the control group. In summary, ADAR1 modulates macrophage M2 polarization via the ADAR1-miR-21-Foxo1-IL-10 axis, thereby suppressing allogeneic graft rejection.-Li, J., Xie, J., Liu, S., Li, X., Zhang, D., Wang, X., Jiang, J., Hu, W., Zhang, Y., Jin, B., Zhuang, R., Yin, W. ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization.

CHIC - Coupling Habitability, Interior and Crust

Science.gov (United States)

Noack, Lena; Labbe, Francois; Boiveau, Thomas; Rivoldini, Attilio; Van Hoolst, Tim

2014-05-01

We present a new code developed for simulating convection in terrestrial planets and icy moons. The code CHIC is written in Fortran and employs the finite volume method and finite difference method for solving energy, mass and momentum equations in either silicate or icy mantles. The code uses either Cartesian (2D and 3D box) or spherical coordinates (2D cylinder or annulus). It furthermore contains a 1D parametrised model to obtain temperature profiles in specific regions, for example in the iron core or in the silicate mantle (solving only the energy equation). The 2D/3D convection model uses the same input parameters as the 1D model, which allows for comparison of the different models and adaptation of the 1D model, if needed. The code has already been benchmarked for the following aspects: - viscosity-dependent rheology (Blankenbach et al., 1989) - pseudo-plastic deformation (Tosi et al., in preparation phase) - subduction mechanism and plastic deformation (Quinquis et al., in preparation phase) New features that are currently developed and benchmarked include: - compressibility (following King et al., 2009 and Leng and Zhong, 2008) - different melt modules (Plesa et al., in preparation phase) - freezing of an inner core (comparison with GAIA code, Huettig and Stemmer, 2008) - build-up of oceanic and continental crust (Noack et al., in preparation phase) The code represents a useful tool to couple the interior with the surface of a planet (e.g. via build-up and erosion of crust) and it's atmosphere (via outgassing on the one hand and subduction of hydrated crust and carbonates back into the mantle). It will be applied to investigate several factors that might influence the habitability of a terrestrial planet, and will also be used to simulate icy bodies with high-pressure ice phases. References: Blankenbach et al. (1989). A benchmark comparison for mantle convection codes. GJI 98, 23-38. Huettig and Stemmer (2008). Finite volume discretization for dynamic

Multikultuurne testimeeskond / Elver Loho

Index Scriptorium Estoniae

Loho, Elver

2008-01-01

Tööst multikultuurses kollektiivis räägivad Videobeti Tallinna kontoris töötavad Mehmet Özekinci, Peter Cercone, Vivek Tyagi, Hua Zhong, Mati Parv ja Karpo Korõtko. Videobet on Playtech Groupi kuuluv rahvusvaheline tarkvarafirma, mis on spetsialiseerunud mänguterminalide ning vastavate haldusrakenduste loomisele. Vt. samas: Quebeclane, kes elab Soomes ja töötab Eestis. Artec Groupis äriarendusjuhina töötavast Martin-Eric Racine'ist. Täielikult Eesti kapitalil põhinev Artec tegeleb spetsiifiliste riistvaralahenduste loomisega

Characteristics and Functionalities of Natural and Bioinspired Nanomaterials

Science.gov (United States)

2012-05-01

Phytomedicine 2002, 9, 560-565. 24. Shen, C. C.; Tsai, S. Y.; Wei, S. L.; Wang, S. T.; Shieh, B. J., et al., Flavonoids isolated from Draconis...from Panax notoginseng using human platelet extraction and HPLC -DAD-ESI-MS/MS. J. Sep. Sci. 2008, 31, 1173-1180. 35. Wang, J.; Xu, J.; Zhong, J. B...339, 131-153. 59. Xin, H. L.; Wu, Y. C.; Su, Y. H.; Sheng, J. Y.; Ling, C. Q., Novel flavonoids from the leaves of Actinidia valvata Dunn

TERT-CLPTM1 locus polymorphism (rs401681 is associated with the prognosis of hepatocellular carcinoma

Directory of Open Access Journals (Sweden)

Lee HW

2017-10-01

Full Text Available Hye Won Lee,1,* Won-Jin Park,2,* Yu-Ran Heo,2 Tae In Park,3 Soo Young Park,4 Jae-Ho Lee2,* 1Department of Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; 2Department of Anatomy, Keimyung University School of Medicine, Daegu, Republic of Korea; 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 4Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea *These authors contributed equally to this work Abstract: Telomere length is associated with the development of hepatocellular carcinoma (HCC, and recent studies have focused on the genetic alteration or polymorphism in telomere-maintaining genes. We examined the clinicopathologic and prognostic value of rs401681 polymorphism, located in the TERT-CLPTM1L locus, in HCC. The relationship between rs401681 variants and telomere length was also analyzed in 156 HCC patients. The rs401681 polymorphism had the following genotype frequencies: C/C in 51.3% of the samples, C/T in 39.7%, and T/T in 9.0%. Telomeres in the tumor samples were 4.04-fold longer, on average, than the telomeres in matched normal samples (SD =1.32, and there were no differences in telomere length according to rs401681 polymorphism (p=0.802. Our results indicate that the rs401681 C allele was significantly associated with increased T and International Union for Cancer Control stages (p<0.01. Univariate and multivariate survival analyses showed that HCC with C allele had poorer prognosis (p<0.01. In conclusion, our findings suggest that rs401681 is a possible prognostic biomarker for HCC patients. Keywords: CLPTM1L polymorphism, hepatocellular carcinoma, TERT-CLPTM1L locus, telomere length

Next-generation sequence detects ARAP3 as a novel oncogene in papillary thyroid carcinoma

Directory of Open Access Journals (Sweden)

Wang QX

2016-11-01

Full Text Available Qing-Xuan Wang, En-Dong Chen, Ye-Feng Cai, Yi-Li Zhou, Zhou-Ci Zheng, Ying-Hao Wang, Yi-Xiang Jin, Wen-Xu Jin, Xiao-Hua Zhang, Ou-Chen Wang Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China Purpose: Thyroid cancer is the most frequent malignancies of the endocrine system, and it has became the fastest growing type of cancer worldwide. Much still remains unknown about the molecular mechanisms of thyroid cancer. Studies have found that some certain relationship between ARAP3 and human cancer. However, the role of ARAP3 in thyroid cancer has not been well explained. This study aimed to investigate the role of ARAP3 gene in papillary thyroid carcinoma. Methods: Whole exon sequence and whole genome sequence of primary papillary thyroid carcinoma (PTC samples and matched adjacent normal thyroid tissue samples were performed and then bioinformatics analysis was carried out. PTC cell lines (TPC1, BCPAP, and KTC-1 with transfection of small interfering RNA were used to investigate the functions of ARAP3 gene, including cell proliferation assay, colony formation assay, migration assay, and invasion assay. Results: Using next-generation sequence and bioinformatics analysis, we found ARAP3 genes may play an important role in thyroid cancer. Downregulation of ARAP3 significantly suppressed PTC cell lines (TPC1, BCPAP, and KTC-1, cell proliferation, colony formation, migration, and invasion. Conclusion: This study indicated that ARAP3 genes have important biological implications and may act as a potentially drugable target in PTC. Keywords: papillary thyroid carcinoma, next-generation sequence, ARAP3, oncogene

Geochemical fingerprints and pebbles zircon geochronology

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science; Volume 125; Issue 7. Geochemical fingerprints and pebbles zircon geochronology: Implications for the provenance and tectonic setting of Lower Cretaceous sediments in the Zhucheng Basin (Jiaodong peninsula, North China). Jin-Long Ni Jun-Lai Liu Xiao-Ling Tang ...

In situ rumen degradability characteristics of rice straw, soybean ...

African Journals Online (AJOL)

In situ rumen degradability characteristics of rice straw, soybean curd residue and peppermint (Mentha piperita) in Hanwoo steer (Bos Taurus coreanae). Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon ...

Overexpression of CFH gene in pterygiumv patients | Bang | Tropical ...

African Journals Online (AJOL)

Overexpression of CFH gene in pterygiumv patients. Man-Seok Bang, Chang Rae Rho, Bong-Hui Kang, Kyong Jin Cho, Chung-Hun Oh. Abstract. Purpose: To investigate the expression of complement factors in pterygium tissues compared to normal conjunctival samples, using next-generation RNA sequencing. Methods: ...

Effect of Malathion on the Microbial Ecology of Activated Sludge

Science.gov (United States)

2015-03-26

L. Long, Y. Fan, J. Gan, J. Fang, and W. Jin, “A review on the detox - ification of organophosphorus compounds by microorganisms,” African Journal of...from pseudomonas diminuta as a model for the detoxication of o-ethyl s-(2-diisopropylaminoethyl) methylphosphonothiolate (vx),” Biochem- ical

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Jin Jeon Sae-Gwang Park Su-Kil Seo Jung Sik Choi Sung-Jae Park Eun Bo Shim Il-Whan Choi Won-Kyo Jung · More Details Abstract Fulltext PDF. Marine algae have been utilized in food as well as medicine products for a variety of purposes.

Interactive Algorithms for Unsupervised Machine Learning

Science.gov (United States)

2015-06-01

in Neural Information Processing Systems, 2013. 14 [3] Louigi Addario-Berry, Nicolas Broutin, Luc Devroye, and Gábor Lugosi. On combinato- rial...Myung Jin Choi, Vincent Y F Tan , Animashree Anandkumar, and Alan S Willsky. Learn- ing Latent Tree Graphical Models. Journal of Machine Learning

Robust numerical simulation of porosity evolution in chemical vapor infiltration III: three space dimension

CERN Document Server

Jin Shi

2003-01-01

Chemical vapor infiltration (CVI) process is an important technology to fabricate ceramic matrix composites (CMC's). In this paper, a three-dimension numerical model is presented to describe pore microstructure evolution during the CVI process. We extend the two-dimension model proposed in [S. Jin, X.L. Wang, T.L. Starr, J. Mater. Res. 14 (1999) 3829; S. Jin. X.L. Wang, T.L. Starr, X.F. Chen, J. Comp. Phys. 162 (2000) 467], where the fiber surface is modeled as an evolving interface, to the three space dimension. The 3D method keeps all the virtue of the 2D model: robust numerical capturing of topological changes of the interface such as the merging, and fast detection of the inaccessible pores. For models in the kinetic limit, where the moving speed of the interface is constant, some numerical examples are presented to show that this three-dimension model will effectively track the change of porosity, close-off time, location and shape of all pores.

[The relationship between acupuncture-moxibustion theory of DOU Hanqing and Neo- Confucianism].

Science.gov (United States)

Li, Baojin; Huang, Longxiang

2018-02-12

For the construction factors of acupuncture-moxibustion theory of DOU Hanqing , a doctor in Jin-Yuan Dynasty, we studied his life, acupuncture-moxibustion theory and culture background in the History of Medicine and Philosophy of Science & Technology. It was found that the major source of DOU Hanqing ' s Confucianism was the CHENG - ZHU Neo-Confucianism. The data show that Neo-Confucianism played an important role in the enrichment of his human nature, spirit, moral cultivation and political talent, making him a scholar in the Jin - Yuan dynasty, also shaping his medical ethics, medical skill and acupuncture-moxibustion theory. The inheritance, development and application of CHENG - ZHU Neo-Confucianism provided the most fundamental thinking, research methods and patterns for DOU Hanqing to interpret the acupuncture classics, summarize his teachers' experience and develop his theoretical system. DOU Hanqing ' s acupuncture-moxibustion practice and theory reached a new level, because he took acupuncture-moxibustion as one of the knowledge investigation and attainment of CHENG - ZHU Neo-Confucianism.

PERSPECTIVE Working towards a community-wide understanding of satellite skin temperature observations

Science.gov (United States)

Shreve, Cheney

2010-12-01

cover, water vapor, cloud cover), they show that skin temperature is clearly a different physical parameter from air temperature and varies from air temperature in magnitude, response to atmospheric conditions, and diurnal phase. Although the accuracy of skin temperature (Tskin) algorithms has improved to within 0.5-1°C for field measurements and clear-sky satellite observations (Becker and Li 1995, Goetz et al 1995, Wan and Dozier 1996), general confusion regarding the physical definition of 'surface temperature' and how it can be used for climate studies has persisted throughout the scientific community and limited the applications of these data (Jin and Dickinson 2010). For example, satellite sea surface temperature was used as evidence of global climate change instead of skin temperature in the IPCC 2001 and 2007 reports (Jin and Dickinson 2010). This work provides clarity in the theoretical definition of temperature variables, demonstrates the difference between air and skin temperature, and aids the understanding of the MODIS Tskin product, which could be very beneficial for future climate studies. As outlined by Jin and Dickinson, 'surface temperature' is a vague term commonly used in reference to air temperature, aerodynamic temperature, and skin temperature. Air temperature (Tair), or thermodynamic temperature, is measured by an in situ instrument usually 1.5-2 m above the ground. Aerodynamic temperature (Taero) refers to the temperature at the height of the roughness length of heat. Satellite derived skin temperature (Tskin) is the radiometric temperature derived from the inverse of Planck's function. While these different temperature variables are typically correlated, they differ as a result of environmental conditions (e.g. land cover and sky conditions; Jin and Dickinson 2010). With an extensive network of Tair measurements, some have questioned the benefits of using Tskin at all (Peterson et al 1997, 1998). Tskin and Tair can vary depending on land cover

Physico-chemical and antioxidant properties of four mango (Mangifera indica L.) cultivars in China.

Science.gov (United States)

Liu, Feng-Xia; Fu, Shu-Fang; Bi, Xiu-Fang; Chen, Fang; Liao, Xiao-Jun; Hu, Xiao-Song; Wu, Ji-Hong

2013-05-01

Four principal mango cultivars (Tainong No.1, Irwin, JinHwang and Keitt) grown in southern China were selected, and their physico-chemical and antioxidant properties were characterized and compared. Of all the four cultivars, Tainong No.1 had highest content of total phenols, ρ-coumaric acid, sinapic acid, quercetin, titratable acidity, citric acid, malic acid, fructose, higher antioxidant activities (DPPH, FRAP) and L(*), lower pH, PPO activity and individual weight. Keitt mangoes showed significantly (pmangoes exhibited significantly (pmango cultivars to be differentiated clearly based on all these physico-chemical and antioxidant properties determined in the study. Copyright © 2012 Elsevier Ltd. All rights reserved.

A data-driven approach to modeling high-density terminal areas: A scenario analysis of the new Beijing, China airspace

Directory of Open Access Journals (Sweden)

Max Z. Li

2017-04-01

Full Text Available Airports are being developed and expanded rapidly in China to accommodate and promote a growing aviation market. The future Beijing Daxing International Airport (DAX will serve as the central airport of the JingJinJi megaregion, knitting the Beijing, Tianjin, and Hebei regions together. DAX will be a busy airport from its inception, relieving congestion and accommodating growth from Beijing Capital International Airport (PEK, currently the second busiest airport in the world in passengers moved. We aim to model terminal airspace designs and possible conflicts in the future Beijing Multi-Airport System (MAS. We investigate standard arrival procedures and mathematically model current and future arrival trajectories into PEK and DAX by collecting large quantities of publicly available track data from historical arrivals operating within the Beijing terminal airspace. We find that (1 trajectory models constructed from real data capture aberrations and deviations from standard arrival procedures, validating the need to incorporate data on historical trajectories with standard procedures when evaluating the airspace and (2 given all existing constraints, DAX may be restricted to using north and east arrival flows, constraining the capacity required to handle the increases in air traffic demand to Beijing. The results indicate that the terminal airspace above Beijing, and the future JingJinJi region, requires careful consideration if the full capacity benefits of the two major airports are to be realized.

Source data supported high resolution carbon emissions inventory for urban areas of the Beijing-Tianjin-Hebei region: Spatial patterns, decomposition and policy implications.

Science.gov (United States)

Cai, Bofeng; Li, Wanxin; Dhakal, Shobhakar; Wang, Jianghao

2018-01-15

This paper developed internationally compatible methods for delineating boundaries of urban areas in China. By integrating emission source data with existing official statistics as well as using rescaling methodology of data mapping for 1 km grid, the authors constructed high resolution emission gridded data in Beijing-Tianjin-Hebei (Jing-Jin-Ji) region in China for 2012. Comparisons between urban and non-urban areas of carbon emissions from industry, agriculture, household and transport exhibited regional disparities as well as sectoral differences. Except for the Hebei province, per capita total direct carbon emissions from urban extents in Beijing and Tianjin were both lower than provincial averages, indicating the climate benefit of urbanization, comparable to results from developed countries. Urban extents in the Hebei province were mainly industrial centers while those in Beijing and Tianjin were more service oriented. Further decomposition analysis revealed population to be a common major driver for increased carbon emissions but climate implications of urban design, economic productivity of land use, and carbon intensity of GDP were both cluster- and sector-specific. This study disapproves the one-size-fits-all solution for carbon mitigation but calls for down-scaled analysis of carbon emissions and formulation of localized carbon reduction strategies in the Jing-Jin-Ji as well as other regions in China. Copyright © 2017 Elsevier Ltd. All rights reserved.

Synthesis and characterization of CuO nanoparticles using strong ...

Indian Academy of Sciences (India)

classified into three types on the basis of their dimension, i.e., one-, two- and ... dependent on the shape, size, composition and structures of the nanocrystals. ..... [43] Liu J, Jin J, Deng Z, Huang S-Z, Hu Z-Y, Wang L, Wang C,. Chen L-H, Li Y, ...

The Situation Awareness Weighted Network (SAWN) Model

Science.gov (United States)

2014-06-01

Administration Task Load Index (NASA- TLX ), a validated research instrument [Human Performance Research Group 1988]. The participants were asked to rate their...analysis”, Human Factors 40(2): 254–276. 17 Human Performance Research Group (1988) NASA- TLX , NASA Ames Research Center, Moffett Field, CA. Jin, Y. and

Anti-tumor activity of polysaccharides extracted from Senecio ...

African Journals Online (AJOL)

*, Bao Zhang, Mingming Han, Xin Jin, Liyuan Sun and Tao Li. Department of ..... Yang J, Li X, Xue Y, Wang N, Liu W. Anti-hepatoma activity and mechanism of corn ... Peng W, Wu JG, Jiang YB, Liu YJ, Sun T, Wu N, Wu CJ. Antitumor activity of ...

78 FR 7791 - Center for Scientific Review; Notice of Closed Meetings

Science.gov (United States)

2013-02-04

...; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5...: Doubletree Hotel Washington, 1515 Rhode Island Avenue NW., Washington, DC 20005. Contact Person: Joanne T.... Place: Washington Plaza Hotel, 10 Thomas Circle NW., Washington, DC 20005. Contact Person: Jin Huang, Ph...

Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism

DEFF Research Database (Denmark)

Petersen, Pia Steen; Jin, Chunyu; Madsen, Andreas Nygaard

2011-01-01

, conceivably due to decreased energy expenditure and adipocyte lipolytic activity.-Petersen, P. S., Jin, C., Madsen, A. N., Rasmussen, M., Kuhre, R., L. Egerod, K. L., Nielsen, L. B., Schwartz. T. W., Holst, B. Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism....

Multimedia over cognitive radio networks algorithms, protocols, and experiments

CERN Document Server

Hu, Fei

2014-01-01

PrefaceAbout the EditorsContributorsNetwork Architecture to Support Multimedia over CRNA Management Architecture for Multimedia Communication in Cognitive Radio NetworksAlexandru O. Popescu, Yong Yao, Markus Fiedler , and Adrian P. PopescuPaving a Wider Way for Multimedia over Cognitive Radios: An Overview of Wideband Spectrum Sensing AlgorithmsBashar I. Ahmad, Hongjian Sun, Cong Ling, and Arumugam NallanathanBargaining-Based Spectrum Sharing for Broadband Multimedia Services in Cognitive Radio NetworkYang Yan, Xiang Chen, Xiaofeng Zhong, Ming Zhao, and Jing WangPhysical Layer Mobility Challen

Reply to 'Comment II on 'Quantum secret sharing based on reusable Greenberger-Horne-Zeilinger states as secure carriers''

International Nuclear Information System (INIS)

Karimipour, V.

2006-01-01

In the preceding Comment [Jian-Zhong Du, Su-Juan Qin, Qiao-Yan Wen, and Fu-Chen Zhu, Phys. Rev. A 74, 016301 (2006)], it has been shown that in a quantum secret sharing protocol proposed in [S. Bagherinezhad and V. Karimipour, Phys. Rev. A 67, 044302 (2003)], one of the receivers can cheat by splitting the entanglement of the carrier and intercepting the secret, without being detected. In this reply we show that a simple modification of the protocol prevents the receivers from this kind of cheating

Design and Implementation of Henan Huinong Client System Based on iOS

Directory of Open Access Journals (Sweden)

Li Yan-Ling

2016-01-01

Full Text Available In order to meet the demands of customers related to agriculture who can obtain some Comprehensive agricultural information service of Henan Province through the intelligent mobile terminal, on the base of the Zhong yuan Rural Information Port integrated platform, employing IOS, Java, Eclipse, XML, SAX technology, we designed and developed Henan Huinong client systems based on ios mobile terminal. This system has achieved the multiple applications, such as agricultural information browsing, network consulting, expert online, crop rermote diagnosis and so on.

RETRACTED: Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population.

Science.gov (United States)

Zhong, Weiqiang; Jiang, Zongpei; Zhou, Tian-Biao

2015-12-01

.1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 Chun-Hua Yang and Tian-Biao Zhou Relationship between the angiotensinogen A1166C gene polymorphism and the risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314566221, first published on February 1, 2015 doi: 10.1177/1470320314566221 Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 Articles published in an issue Guohui Liu, Tian-Biao Zhou, Zongpei Jiang, and Dongwen Zheng Association of ACE I/D gene polymorphism with T2DN susceptibility and the risk of T2DM developing into T2DN in a Caucasian population Journal of Renin-Angiotensin-Aldosterone System March 2015 16: 165-171, first published on November 14, 2014 doi: 10.1177/1470320314557849 Weiqiang Zhong, Zhongliang Huang, Yong Wu, Zongpei Jiang, and Tian-Biao Zhou Association of aldosterone synthase (CYP11B2) gene polymorphism with IgA nephropathy risk and progression of IgA nephropathy Journal of Renin-Angiotensin-Aldosterone System September 2015 16: 660-665, first published on August 20, 2014 doi: 10.1177/1470320314524011.

Menschenrechtliche Vorgaben an das Aufenthaltsrecht in der jüngeren Rechtsprechung des EGMR / Matthias Lehnert

Index Scriptorium Estoniae

Lehnert, Matthias

2016-01-01

Inimõiguste konventsiooni (eelkõige artiklite 3 ja 8) tõlgendamisest asüülitaotlejate kohtlemisel ELi liikmesriikides; Euroopa Inimõiguste Kohtu vastavast praktikast (nt Tarakhel vs. Šveits; V.M. vs. Belgia; Mohammed vs. Austria, Khan vs. Saksamaa)

Comment on 'Modeling of Convective-Stratiform Precipitation Processes: Sensitivity to Partitioning Methods' by Matthias Steiner

Science.gov (United States)

Lang, Steve; Tao, W.-K.; Simpson, J.; Ferrier, B.

2003-01-01

Despite the obvious notion that the presence of hail or graupel is a good indication of convection, the model results show this does not provide an objective benchmark partly due to the unrealistic presence of small amounts of hail or graupel throughout the anvil in the model but mainly because of the significant amounts of hail or graupel, especially in the tropical TOGA COARE simulation, in the transition zone. Without use of a "transition" category, it is open to debate as how this region should best be defined, as stratiform or as convective. So, the presence of significant hail or graupel contents in this zone significantly degrades its use an objective benchmark for convection. The separation algorithm comparison was done in the context of a cloud-resolving model. These models are widely used and serve a variety of purposes especially with regard to retrieving information that cannot be directly measured by providing synthetic data sets that are consistent and complete. Separation algorithms are regularly applied in these models. However, as with any modeling system, these types 'of models are constantly being improved to overcome any known deficiencies and make them more accurate representations of observed systems. The presence of hail and graupel in the anvil and the bias towards heavy rainfall rates are two such examples of areas that need improvement. Since, both of these can effect the perceived performance of the separation algorithms, the Lang et al. (2003) study did not want to overstate the relative performance of any specific algorithms.

Novel phytoceramides containing fatty acids of diverse chain lengths are better than a single C18-ceramide N-stearoyl phytosphingosine to improve the physiological properties of human stratum corneum

Directory of Open Access Journals (Sweden)

Oh MJ

2017-09-01

Full Text Available Myoung Jin Oh,1 Young Hoon Cho,1 So Yoon Cha,1 Eun Ok Lee,2 Jin Wook Kim,2 Sun Ki Kim,2 Chang Seo Park1 1Department of Chemical and Biochemical Engineering, Dongguk University, Chung-gu, Seoul, 2LCS Biotech, Gwonseon-gu, Suwon-si, Gyeonggi-do, Republic of Korea Abstract: Ceramides in the human stratum corneum (SC are a mixture of diverse N-acylated fatty acids (FAs with different chain lengths. C24 is the major class of FAs of ceramides. However, there are also other classes of ceramides with diverse chain lengths of FAs, and these lengths generally range from C16 to C26. This study aimed to prepare several types of phytoceramide containing diverse chain lengths of N-acylated FAs and compare them with C18-ceramide N-stearoyl phytosphingosine (NP in terms of their effects on the physiological properties of the SC. We chose natural oils, such as horse fat oil, shea butter, sunflower oil, and a mixture of macadamia nut, shea butter, moringa, and meadowfoam seed oil, as sources of FAs and phytosphingosine as a sphingoid backbone to synthesize diverse phytoceramides. Each phytoceramide exhibited a distinctive formation of the lamellar structure, and their FA profiles were similar to those of their respective natural oil. The skin barrier properties, as analyzed in human skin, clearly demonstrated that all the phytoceramides improved the recovery rate of the damaged SC and enhanced hydration better than C18-ceramide NP did. In conclusion, natural oil-derived phytoceramides could represent a novel class of ceramides for cosmetic applications in the development of an ideal skin barrier moisturizer. Keywords: fatty acid, chain length, phytoceramide, skin barrier, natural oil

Synthesis of exfoliated PA66 nanocomposites via interfacial ...

Indian Academy of Sciences (India)

[24] Kang M, Myung S J and Jin H J 2006 Polymer 47 3961. [25] Haggenmueller R ... [32] Shirali H, Rafizadeh M and Taromi F A 2014 J. Compos. Mater. 48 301 ... [37] Hwang S Y, Khaydarov A A, Park J Y, Yoo E S and Im S S. 2011 Macromol.

Impact Evaluation of the National Writing Project's College-Ready Writing Project in High Poverty Rural Districts

Science.gov (United States)

Gallagher, H. Alix; Arshan, Nicole; Woodworth, Katrina

2016-01-01

Writing is an essential skill for participating in modern American society. Although it is crucial to careers and civic engagement, student writing falls far short of national expectations (College Board, 2004; NCES, 2012; Persky, Daane, & Jin, 2003). The Common Core State Standards (CCSS) seek to increase the rigor of writing instruction…

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

pp 257-266 Full Papers ... complexes of rhodium - Synthesis, structure and, spectral and electrochemical properties ... pp 267-273 Full Papers ... pp 275-281 Full Papers ... Yuliang Che Hua Yang Hongxiao Jin Chunxin Lu Ziyang Liu ... Excited state dynamics of 9,9'-bianthryl in room temperature ionic liquids as revealed by ...

Estimation of mechanical properties of single wall carbon nanotubes ...

Indian Academy of Sciences (India)

Molecular mechanics; single wall carbon nanotube; mechanical proper- ... Fracture Mechanics); Rossi & Meo 2009). Furthermore, the work carried out by Natsuki & Endo. (2004), Xiao et al (2005) and Sun & Zhao (2005) in the direction of ..... Jin Y and Yuan F G 2003 Simulation of elastic properties of single walled carbon ...

Targeting CD81 to Prevent Metastases in Breast Cancer

Science.gov (United States)

2015-10-01

height) and/or by bioluminescence using the in vivo optical imaging system ( IVIS 100, Xenogen). Mice were sacrificed when s.c. tumor size reached 2...Hong IK, Byun HJ, Lee J, Jin YJ, Wang SJ, Jeoung DI, et al. The tetraspanin CD81 protein increases melanoma cell motility by up-regulating

Computer-Based English Language Testing in China: Present and Future

Science.gov (United States)

Yu, Guoxing; Zhang, Jing

2017-01-01

In this special issue on high-stakes English language testing in China, the two articles on computer-based testing (Jin & Yan; He & Min) highlight a number of consistent, ongoing challenges and concerns in the development and implementation of the nationwide IB-CET (Internet Based College English Test) and institutional computer-adaptive…

Matuyama/Brunhes Polarity Transition in Owens Lake, CA, Sediment

Science.gov (United States)

Liddicoat, Joseph; Kravchinsky, Vadim

2014-05-01

The complexity of the Matuyama/Brunhes (M/B) polarity transition is becoming better understood from investigations of volcanic rocks (Coe et al., 2004), loess (Jin et al., 2012; Evans et al., 2011; Kravchinsky, 2013), and marine (Clement and Opdyke, 1982; Hartl and Tauxe, 1996; Macri et al., 2010) and lacustrine (Valet et al., 1988; Sagnotti et al., 2013) sediments. The transition appears to include a brief interval of normal polarity prior to the entry into the Brunhes Normal Chron (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011), and the transition has Virtual Geomagnetic Poles rapidly moving from the Southern Hemisphere to the Northern Hemisphere (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011; Sagnotti et al., 2013). The M/B polarity transition is recorded in exposed Pleistocene lake sediments near Bishop, CA, where the brief interval of normal polarity noted above is present and the change from full reverse to full normal polarity occurs rapidly. The brief interval of normal polarity is recorded at two sites separated laterally by about 150 m and is in single hand samples measured at vertical spacing of 2.0-2.5 cm using six samples per measured level and alternating field demagnetization at 20 mT (Liddicoat, 1993, Table 1 and Fig. 8). The siltstone is unweathered glacial flour from the Sierra Nevada that borders the western side of Owens Valley where the sediments were deposited in Owens Lake. In the siltstone, the majority of the samples have a percentage of about 60 percent where the grain diameter is less than 63 micrometres, and in those samples there is about a five percent fraction when the diameter is two micrometres or less. The Total Inorganic Carbon in most samples is about 0.25 percent (Bergeron, 2013), and magnetite is the dominant carrier of the magnetization (Liddicoat, 1993). The palaeomagnetic directions recording the terminus of the full M/B transition, which occurs before the field intensity is completely recovered, spans no

Unexpected dehydrogenation behaviors of the 2LiBH4-MgH2 composite confined in a mesoporous carbon scaffold

CSIR Research Space (South Africa)

Wang, K

2014-11-01

Full Text Available Chemistry C Vol. 118(46) Unexpected Dehydrogenation Behaviors of the 2LiBH4−MgH2 Composite Confined in a Mesoporous Carbon Scaffold Kuikui Wang,†,‡ Xiangdong Kang,*,‡ Yujie Zhong,‡ Chaohao Hu,§ Jianwei Ren,⊥ and Ping Wang*,‡ †University... of Science and Technology of China, Hefei 230026, P. R. China ‡Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, P. R. China §Guangxi Key Laboratory of Information Materials...

Acupuncture Treatment of Abducent Paralysis

Institute of Scientific and Technical Information of China (English)

任辉; 王涵; 武连仲; 杜元灏

2006-01-01

@@ Abducent paralysis is a kind of the pathological change of the cranial nerve, manifested mainly by the clinical symptoms of inward strabismus, limited abduction of the eyeball and double vision. It is believed in modern medicine that this disease can be caused by pathological change of the pons, basicranial metastatic carcinoma, elevated intracranial pressure, and also by inflammation in the head and face, rupture of local small blood vessels or traumatic injury. Now, Prof. WU Lian-zhong's experience in the treatment of abducent paralysis is reported in the following.

Browse Title Index

African Journals Online (AJOL)

Items 6201 - 6250 of 11090 ... Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon. Vol 10, No 65 (2011), In vitro activity of certain antimicrobial agents in combination with Augouardia letestii hexane extracts against methicillin-resistant Staphylococcus ...

Frequency upconversion in catechin assisted : - square nanoplates

Indian Academy of Sciences (India)

VAIRAPPERUMAL TAMILMANI

2017-11-25

Nov 25, 2017 ... out to be a prominent ligand for its coordination on the surface of the ..... C 113. 14702. 12. Jin J, Gu Y J, Man C W Y, Cheng J, Xu Z, Zhang Y, Wang .... Ding B, Han C, Zheng L, Zhang J, Wang R and Tang. Z 2015 Tuning ...

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

Cultural Foundations of Learning: East and West

Science.gov (United States)

Li, Jin

2012-01-01

Western and East Asian people hold fundamentally different beliefs about learning that influence how they approach child rearing and education. Reviewing decades of research, Dr. Jin Li presents an important conceptual distinction between the Western mind model and the East Asian virtue model of learning. The former aims to cultivate the mind to…

Kaunistatud elamu / Krista Kodres

Index Scriptorium Estoniae

Kodres, Krista, 1957-

2005-01-01

Eestis 16.-18. sajandil. Etikud ja trepid. Burchardi piltetikud (1630.-1640. aastad, Arent Passer?). Fassaadiportaalid (A. Passer, Dionysius Passer, Berent Geistman). Narva ja Pärnu portaalid (Matthias Daus, Otto Koste, Jan van der Capelle).Uued uksed (Elert Thiele töökoda, Abraham Friedrich Pahlmann). "Pildid" fassaadil (A. Passeri töökoda). Passeri voorused ja protestantlik eetika (A. Passeri töökoda, Jakob Damm)). Viilukivid (Hans Damm, Jakob Damm, Winant Nacke, Johann Georg Heroldt). Siseportaalid (Clemens Pale, A. Passer, Christian Ackermann). Thomas von zur Mühleni maja siseportaal (1687). Kaunistatud aken (A. Passeri ja W. Nacke töökojad). Kamin. Paraadne trepp. Bibliograafia lk. 446-448

Europe of energy and transports

International Nuclear Information System (INIS)

Ruete, M.

2006-01-01

The Directorate-General for Energy and Transport (DG TREN), based in Brussels, reports to Jacques Barrot, Vice-President of the European Commission, Commissioner for Transport and Andris Piebalgs, Commissioner for Energy. The Directorate-General for Energy and Transport is headed by Matthias Ruete and has a staff of over 1000 people in ten Directorates located in Brussels and Luxembourg. In addition to the development of Community transport and energy policies, including dealing with State aid, the Directorate-General is responsible for managing the financial support programmes for the trans-European networks, technological development and innovation. In this paper, M. Ruete tells us more about these missions

Section 5: Adapting Requirements Practices in Different Domains

Science.gov (United States)

Robinson, William

Technology has a tremendous impact on society. In recent years, the Internet, World Wide Web, and Web 2.0 has changed the nature of commerce, government, and of course software development. It affects the practices of producing requirements and as well as the kinds of systems to be designed. The effect of converging technologies on the role of requirements engineering is considered in the first article by Matthias Jarke, while the effect of technology on requirements practices is considered in the second article by Walt Scacchi. Together, they provide theoretical and practical perspective on requirements engineering issues faced in a modern, technology driven world.

Superconductivity and magnetism: From antagonism to mutual interplay

International Nuclear Information System (INIS)

Steglich, Frank

2007-01-01

In this paper, a brief survey is given on a number of research activities devoted to exploring the relationship between superconductivity and magnetism in f-electron systems. The starting point for these activities has been the pioneering work of 1958 by Matthias and coworkers illustrating the antagonistic nature of the two phenomena. Subsequent efforts concerned the investigation of Kondo superconductors and Kondo-lattice systems (in the 1970s), heavy-fermion metals (in the 1980s and 90s) and quantum critical materials (in the last decade). The latter systems are especially interesting as they promise a deeper insight into the mutual interplay between unconventional superconductivity and magnetism

Orthotopic liver transplantation after the combined use of locoregional therapy and sorafenib for advanced hepatocellular carcinoma

Directory of Open Access Journals (Sweden)

Yoo EJ

2013-06-01

Full Text Available Eun Jin Yoo,1,* Hye Sun Shin,1,* Seung Up Kim,1,2,7 Dong Jin Joo,3,4 Jun Yong Park,1,2,7 Gi Hong Choi,3 Do Young Kim,1,2,7 Sang Hoon Ahn,1,2,7 Jinsil Seong,5 Myung Joo Koh,6 Kwang-Hyub Han,1,2,7 Chae Yoon Chon1,2,7 1Department of Internal Medicine, 2Institute of Gastroenterology, 3Department of Surgery, 4Research Institute for Transplantation, 5Department of Radiation Oncology, 6Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea; 7Liver Cirrhosis Clinical Research Center, Seoul, South Korea *These authors contributed equally to this work Abstract: We herein report a patient with advanced hepatitis B virus-related hepatocellular carcinoma (HCC beyond the Milan criteria. He underwent orthotopic liver transplantation after successful HCC downstaging that satisfied the University of California, San Francisco criteria, using concurrent chemoradiation therapy with a combination of repeated hepatic arterial infusion chemotherapy (HAIC and sorafenib. A 52-year-old male was diagnosed with advanced hepatitis B virus-related HCC beyond the Milan criteria. He underwent concurrent chemoradiation therapy (50 Gy with 20 fractions over 5 weeks with HAIC using 5-fluorouracil at a dose of 500 mg/day, which was administered during the first and fifth weeks of radiation therapy as an initial treatment modality. This was followed by the combined use of HAIC using 5-fluorouracil (500 mg/m2 for 5 hours on days 1–3 and cisplatin (60 mg/m2 for 2 hours on day 2 every 4 weeks (twelve cycles and sorafenib (from the third to the twelfth cycle of HAIC to treat the remaining HCC. Because a remarkable decrease in the tumor burden that satisfied the University of California, San Francisco criteria was observed after these combination treatments, the patient underwent orthotopic liver transplantation with curative aim and survived for 11 months without evidence of HCC recurrence. Keywords: hepatocellular carcinoma, liver transplantation

[Spatial temporal differentiation of product-based and consumption-based CO2 emissions and balance in the Beijing-Tianjin-Hebei region: an economic input- output analysis].

Science.gov (United States)

Wang, Hao; Chen, Cao-cao; Pan, Tao; Liu, Chun-lan; Chen, Long; Sun, Li

2014-09-01

Distinguishing product-based and consumption-based CO2 emissions in the open economic region is the basis for differentiating the emission responsibility, which is attracting increasing attention of decision-makers'attention. The spatial and temporal characteristics of product-based and consumption-based CO2 emissions, as well as carbon balance, in 1997, 2002 and 2007 of JING- JIN-JI region were analyzed by the Economic Input-Output-Life Cycle Assessment model. The results revealed that both the product- based and consumption-based CO2 emissions in the region have been increased by about 4% annually. The percentage of CO2 emissions embodied in trade was 30% -83% , to which the domestic trading added the most. The territorial and consumption-based CO2 emissions in Hebei province were the predominant emission in JING-JIN-JI region, and the increasing speed and emission intensity were stronger than those of Beijing and Tianjin. JING-JIN-JI region was a net inflow region of CO2 emissions, and parts of the emission responsibility were transferred. Beijing and Tianjin were the net importers of CO2 emissions, and Hebei was a net outflow area of CO2 emissions. The key CO2 emission departments in the region were concentrated, and the similarity was great. The inter-regional mechanisms could be set up for joint prevention and control work. - Production and distribution of electricity, gas and water and smelting and pressing of metals had the highest reliability on CO2 emissions, and took on the responsibility of other departments. The EIO-LCA model could be used to analyze the product-based and consumption-based CO2 emissions, which is helpful for the delicate management of regional CO2 emissions reduction and policies making, and stimulating the reduction cooperation at regional scale.

Optimal Attitude Control of Agile Spacecraft Using Combined Reaction Wheel and Control Moment Gyroscope Arrays

Science.gov (United States)

2015-12-01

communications between the MicroAuto Box and the ground station computer [58]. SimSat users design experiments in the MATLAB® Simulink environment and use an...Guidance, Control, and Dynamics, vol. 35, no. 4, pp. 1094–1103, 2012. [44] Z. Sun, L. Zhang, G. Jin, and X. Yang, “Analysis of inertia dyadic uncertainty

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 32; Issue 4. Molecular cloning and expression of the C-terminus of spider flagelliform silk protein from Araneus ventricosus. Kwang Sik Lee Bo Yeon Kim Yeon Ho Je Soo Dong Woo Hung Dae Sohn Byung Rae Jin. Articles Volume 32 Issue 4 June 2007 pp 705-712 ...

Preliminary analysis on tectonic movement and uranium metallization in Kang-Dian the earth's axis

International Nuclear Information System (INIS)

Luo Yiyue; Wei Mingji; Ma Guangzhong

1998-01-01

On the basis of analyzing available data the authors expounds the regional geology, tectonic movement, as well as the relationship between geological evolution and uranium metallization in Kang-Dian the earth's axis and propose that the Jinning Period (960-1006 Ma) is the first metallogenic epoch of uranium in Kang-Dian the earth's axis

Formation of Sphere-like Au Nanoparticles on Substrate with Laser Illumination and Their Surface Plasmon Behaviors

Science.gov (United States)

2010-09-17

depends on the material type of the substrate and the metal melting temperature. Based on the reaction -free theory, the contact angle of an Au...Luo, Q.; Zhang, X. Nano Lett. 2004, 4, 1085-1088. (13) Maillard , M.; Huang, P.; Brus, L. Nano Lett. 2003, 3, 1611-1615. (14) Jin, R.; Cao, Y. C.; Hao

The 3rd international conference on reproductive immunology in Shanghai: September 27-29, 2013. Shanghai, China.

Science.gov (United States)

Du, MeiRong; Piao, HaiLan; Li, DaJin

2014-03-01

After the first and second international conferences on reproductive immunology held by Dr. DaJin Li in Shanghai, the related investigators all over the world hope to get together to share their latest findings with each other. Drs. DaJin Li and MeiRong Du sponsored and organized the third international conference on reproductive immunology at the Obstetrics and Gynecology Hospital affiliated with Fudan University, Shanghai, China, in the autumn of 2013. This congress brought together more than 100 International and National investigators representing a wide range of scientific disciplines. All the investigators actively work on reproductive immunology using human or large and small animal models. A range of reproductive immunological topics including the maternal-fetal immune regulation, reproductive tract mucosal immunology, immunocontraception, and pregnancy complications were highlighted and discussed in this conference. This conference supplied a good platform for the international reproductive immunologists to exchange their latest study progression and discuss the development direction of reproductive immunology in the near future. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Optimized construction of biogas plants; Optimierte Bauweise fuer Biogasanlagen

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-09-19

Within the conference of the International Trade Fair for Biogas Plant Technology at 21st February, 2012 in Berlin, the following lectures were held: (1) Optimized dimensions of containers for small systems of liquid manure (Manfred Thalmann); (2) Microferm mini biogas plants (Bart Brouwer); (3) Fermentation of stackable biomass in rural biogas plant - The DeNaBa system (Christian Deterding); (4) The Sauter Biogas System for the fermentation of liquid manure, solid dung, and other residual materials (Stefan Sauter); (5) Bio-electricity: Controllable power generation by means of biogas plants (Matthias Sonnleitner); (6) Reduction of the effort and increase of the yield using UDR fixed bed technology (Alfred van den Berg); (7) Prestressed concrete container for biogas plants: Area of application - quality - options (Harald Feldmann); (8) Corrosion protection of agricultural and communal biogas plants (Michael Normann); (9) Fundamentals of efficient and effective flow generation in biogas plants (Kay Rotalski); (10) Rotary piston screw pistons and eccentric screw pumps (Thorsten Gilles).

Energy technology of tomorrow. Strategies and concepts. Conference contributions; Energietechnik von morgen. Strategien und Konzepte. Konferenzbeitraege

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

Within the meeting 'Energy technology of tomorrow - Strategies and concepts' at 12th June, 2007 in Nuremberg (Federal Republic of Germany) the following lectures were held: (1) Cluster energy technology (Klaus Hassmann); (2) Dimension of future energy supply - prognoses/strategies/concepts (Ludger Mohrbach); (3) Future technologies for a CO{sub 2} reduced energy supply (Helmut Tschaffon); (4) Energy research - New specific targets and results (Hartmut Spliethoff); (5) Technological progress for future power plants at RWE (Frank Schwending); (6) Future potential of the generation of syngas with different energy sources (Sebastian Muschelknautz); (7) Innovations in plant engineering - on the way to a CO{sub 2} free power plant (Tobias Jockenhoevel); (8) Solar thermal power plants - status and prospects (Robert Piltz-Paal); (9) Perspectives of the generation of liquid hydrocarbons using nuclear energy (Kurt Kugeler); (10) Application of the MPG gasification technology in the refining of Canadian tar sands (Matthias Mueller-Hagedorn); (11) Perspectives for a sustainable supply with energy carriers (Ulrich Balfanz).

SwinDeW-C: A Peer-to-Peer Based Cloud Workflow System

Science.gov (United States)

Liu, Xiao; Yuan, Dong; Zhang, Gaofeng; Chen, Jinjun; Yang, Yun

Workflow systems are designed to support the process automation of large scale business and scientific applications. In recent years, many workflow systems have been deployed on high performance computing infrastructures such as cluster, peer-to-peer (p2p), and grid computing (Moore, 2004; Wang, Jie, & Chen, 2009; Yang, Liu, Chen, Lignier, & Jin, 2007). One of the driving forces is the increasing demand of large scale instance and data/computation intensive workflow applications (large scale workflow applications for short) which are common in both eBusiness and eScience application areas. Typical examples (will be detailed in Section 13.2.1) include such as the transaction intensive nation-wide insurance claim application process; the data and computation intensive pulsar searching process in Astrophysics. Generally speaking, instance intensive applications are those processes which need to be executed for a large number of times sequentially within a very short period or concurrently with a large number of instances (Liu, Chen, Yang, & Jin, 2008; Liu et al., 2010; Yang et al., 2008). Therefore, large scale workflow applications normally require the support of high performance computing infrastructures (e.g. advanced CPU units, large memory space and high speed network), especially when workflow activities are of data and computation intensive themselves. In the real world, to accommodate such a request, expensive computing infrastructures including such as supercomputers and data servers are bought, installed, integrated and maintained with huge cost by system users

Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications

Directory of Open Access Journals (Sweden)

Chen C

2014-02-01

Full Text Available Chuang Chen,1 Jing-Ping Yuan,2,3 Wen Wei,1 Yi Tu,1 Feng Yao,1 Xue-Qin Yang,4 Jin-Zhong Sun,1 Sheng-Rong Sun,1 Yan Li2 1Department of Breast and Thyroid Surgery, Wuhan University, Renmin Hospital, Wuhan, 2Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, 3Department of Pathology, The Central Hospital of Wuhan, Wuhan, 4Medical School of Jingchu University of Technology, Jingmen, People’s Republic of China Background: Hormone receptors, including the estrogen receptor and progesterone receptor, human epidermal growth factor receptor 2 (HER2, and other biomarkers like Ki67, epidermal growth factor receptor (EGFR, also known as HER1, the androgen receptor, and p53, are key molecules in breast cancer. This study evaluated the relationship between HER2 and hormone receptors and explored the additional prognostic value of Ki67, EGFR, the androgen receptor, and p53. Methods: Quantitative determination of HER2 and EGFR was performed in 240 invasive breast cancer tissue microarray specimens using quantum dot (QD-based nanotechnology. We identified two subtypes of HER2, ie, high total HER2 load (HTH2 and low total HER2 load (LTH2, and three subtypes of hormone receptor, ie, high hormone receptor (HHR, low hormone receptor (LHR, and no hormone receptor (NHR. Therefore, breast cancer patients could be divided into five subtypes according to HER2 and hormone receptor status. Ki67, p53, and the androgen receptor were determined by traditional immunohistochemistry techniques. The relationship between hormone receptors and HER2 was investigated and the additional value of Ki67, EGFR, the androgen receptor, and p53 for prediction of 5-year disease-free survival was assessed. Results: In all patients, quantitative determination showed a statistically significant (P<0.001 negative correlation between HER2 and the hormone receptors and a significant

GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells

Directory of Open Access Journals (Sweden)

Wang L

2015-03-01

Full Text Available Ling Wang,1 Yanli An,2 Chenyan Yuan,3 Hao Zhang,2 Chen Liang,2 Fengan Ding,2 Qi Gao,1 Dongsheng Zhang4 1Department of Ultrasonography, Zhong Da Hospital, Medical School, Southeast University, Nanjing, People’s Republic of China; 2Medical School, Southeast University, Nanjing, People’s Republic of China; 3Department of Clinical Laboratory, Zhong Da Hospital, Medical School, Southeast University, Nanjing, People’s Republic of China; 4Jiangsu Key Laboratory for Biomaterials and Devices, Medical School, Southeast University, Nanjing, People’s Republic of China Background: Targeted delivery is a promising strategy to improve the diagnostic imaging and therapeutic effect of cancers. In this paper, novel cetuximab (C225-conjugated, gemcitabine (GEM-containing magnetic albumin nanospheres (C225-GEM/MANs were fabricated and applied as a theranostic nanocarrier to conduct simultaneous targeting, magnetic resonance imaging (MRI, and double-targeted thermochemotherapy against pancreatic cancer cells. Methods: Fe3O4 nanoparticles (NPs and GEM co-loaded albumin nanospheres (GEM/MANs were prepared, and then C225 was further conjugated to synthesize C225-GEM/MANs. Their morphology, mean particle size, GEM encapsulation ratio, specific cell-binding ability, and thermal dynamic profiles were characterized. The effects of discriminating different EGFR-expressing pancreatic cancer cells (AsPC-1 and MIA PaCa-2 and monitoring cellular targeting effects were assessed by targeted MRI. Lastly, the antitumor efficiency of double/C225/magnetic-targeted and nontargeted thermochemotherapy was compared with chemotherapy alone using 3-(4, 5-dimethyl-2-thiazolyl-2,5-diphenyl-2H-tetrazolium bromide (MTT and flow cytometry (FCM assay. Results: When treated with targeted nanospheres, AsPC-1 cells showed a significantly less intense MRI T2 signal than MIA PaCa-2 cells, while both cells had similar signal strength when incubated with nontargeted nanospheres. T2 signal

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response

Directory of Open Access Journals (Sweden)

Li L

2012-02-01

Full Text Available Rolf P Kreutz1,2, Perry Nystrom2, Yvonne Kreutz2, Jia Miao2, Zeruesenay Desta2, Jeffrey A Breall1, Lang Li2, ChienWei Chiang2, Richard Kovacs1, David A Flockhart2, Yan Jin21Krannert Institute of Cardiology, 2Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, IN, USABackground: The metabolic activation of clopidogrel is a two-step process. It has been suggested that paraoxonase-1 (PON1 is a rate-limiting enzyme in the conversion of 2-oxo-clopidogrel to an active thiol metabolite. Conflicting results have been reported in regard to (1 the association of a common polymorphism of PON1 (Q192R with reduced rates of coronary stent thrombosis in patients taking clopidogrel and (2 its effects on platelet inhibition in patient populations of European descent. Methods: Blood samples from 151 subjects of mixed racial background with established coronary artery disease and who received clopidogrel were analyzed. Platelet aggregation was determined with light transmittance aggregometry and VerifyNow® P2Y12 assay. Genotyping for cytochrome P450 2C19 (CYP2C19*2 and *3 and PON1 (Q192R polymorphisms was performed.Results: Carriers of CYP2C19*2 alleles exhibited lower levels of platelet inhibition and higher on-treatment platelet aggregation than noncarriers. There was no significant difference in platelet aggregation among PON1 Q192R genotypes. Homozygous carriers of the wild-type variant of PON1 (QQ192 had similar on-treatment platelet reactivity to carriers of increased-function variant alleles during maintenance clopidogrel dosing, as well as after administration of a clopidogrel 600 mg loading dose.Conclusion: CYP2C19*2 allele is associated with impaired platelet inhibition by clopidogrel and high on-treatment platelet aggregation. PON1 (Q192R polymorphism does not appear to be a significant determinant of clopidogrel response.Keywords: PON1, platelet, aggregation, cytochrome P450 enzymes

The effectiveness of traditional Chinese medicine-based lifestyle interventions on biomedical, psychosocial, and behavioral outcomes in individuals with type 2 diabetes: A systematic review with meta-analysis.

Science.gov (United States)

Yu, Xingfeng; Chau, Janita P C; Huo, Lanting

2018-04-01

Integrative diabetes care, which combines conventional diabetes therapy with traditional Chinese medicine (TCM)-based interventions, has gained popularity worldwide. Numerous TCM-based lifestyle modification approaches have been proposed for individuals with type 2 diabetes (T2DM). To synthesize and present the best available evidence on the effectiveness of TCM-based lifestyle interventions in individuals with T2DM. We undertook a systematic review of randomized controlled trials or controlled clinical trials. Six English and four Chinese electronic databases were searched from their inceptions to December 2016. Trials investigating the effectiveness of various TCM-based lifestyle interventions among adults with T2DM were reviewed. Studies were excluded if TCM-based lifestyle interventions were only part of the intervention regimen. Two reviewers independently selected studies according to pre-specified inclusion and exclusion criteria and appraised the risk of bias of the included studies. One reviewer extracted details of the included studies and the second reviewer checked the extracted data critically. When feasible, data were statistically pooled for meta-analysis. Otherwise, narrative summaries were used. Twenty-four studies were included. The pooled analysis of the eight studies on tai chi showed tai chi practice for at least 150 min per week was beneficial in lowering glycosylated hemoglobin (mean difference, -1.48%; 95%CI, -2.58% to -0.39%; p < 0.001). Tai chi was effective in reducing fasting blood glucose (mean difference, -1.14 mmol/L; 95%CI, -1.78 to -0.50 mmol/L; p < 0.001) and body mass index (mean difference, -0.62; 95%CI, -1.14 to -0.11; p = 0.02), and improving quality of life. The effects of tai chi on blood pressure and waist circumference were inconclusive due to the limited number of studies. The meta-analysis of the 12 studies on ba duan jin demonstrated beneficial effects on glycosylated hemoglobin (mean difference, -0

Oxytocin: the neuropeptide of love reveals some of its secrets.

Science.gov (United States)

Neumann, Inga D

2007-04-01

The neuropeptide oxytocin is synthesized in the brain and released from neurohypophyseal terminals into the blood and within defined brain regions that regulate emotional, cognitive, and social behaviors. A recent study of CD38-/- mice (Jin et al., 2007) has demonstrated an essential role for the transmembrane receptor CD38 in secretion of oxytocin into the blood.

Effect of indole-3-butyric acid (IBA) on in vitro root induction in ...

African Journals Online (AJOL)

ishtiaq

2012-03-08

Mar 8, 2012 ... physiological analyses of photo autotrophic callus cultures of the fern Platycerium coronarium (Koenig) under CO2 enrichment. J. Exp. Bot. 46 (10): 1535-1542. Liu C, Zhu J, Liu Z, Li L, Pan R, Jin L (2002). Exogenous auxin effects on growth and phenotype of normal and hairy roots of Pueraria lobata. (Wild.) ...

Directory of Czechoslovak Officials; a Reference Aid

Science.gov (United States)

1988-07-14

Jaroslav; KSS Barilla , Jan KSS Horvath, Stefan: A’SS Bartak, Stel’an KSS Horvathova, Marta: KSC Barton, Jaroslav Hricko, Peter: KSS Benyo, Matus: KSS...61 Bilek. Jin 78 Banarova. Eva is Bilek, /denck 4’) Barak, Ladislav 71 Biro~s, Branislav 10.40.41, Barilla , Jan .11 Bisko. fir,, Harlot’s, Paulina 6

Emissive lead(II) benzenedicarboxylate metal-organic frameworks

Indian Academy of Sciences (India)

Abdul Malik P Peedikakkal

2018-04-16

Apr 16, 2018 ... Jang E, Jun S, Jang H, Lim J, Kim B and Kim Y 2010. White-light-emitting ... 2837; (b) Li Y-F, Wang D, Liao Z, Kang Y, Ding. W-H, Zheng X-J, Jin L-P 2016 .... Zuo J-L and Zhou H-C 2007 Synthesis and Characteri- zations of a ...

an overview on the application of polymerase chain reaction (pcr)

African Journals Online (AJOL)

DR. AMINU

Hill New York Pp818. Chul, W.P., Jang-Hee, H., Jin-Hyeok, J. et al (2004). Detection rates of Bacteria in chronic Otitis. Media with Effusion in Children, Journal of. Korean Medical Sciences 19: 735-738. Cockerill, F.R. and Smith, T.F. (2002). Rapid-Cycle real time PCR: A revolution of clinical. Microbiology. ASM News 68:2.

Sensing of DNA by Graphene-on-Silicon FET Structures at DC and 101 GHz

Science.gov (United States)

2015-01-01

is just DIDC= Irms ¼ jIN I0j= Irms where Irms is the rms fluctuation dominated by a fast (white noise) component from the current source (Keithley 2400...and a slow (drift) component from the graphene. The noise was observed over a 600 s time span with the graphene kept dry, and yielded Irms 8:5

On the diurnal ranges of Sea Surface Temperature (SST) in the ...

Indian Academy of Sciences (India)

(Solomon and Jin 2005). The diurnal change in. SST has also been examined to study the possible feedbacks on the atmosphere (Clayson and Chen. 2002; Bernie et al 2007). Solar heating of the sea surface in low-wind conditions can lead to the development of a stable warm layer of a few meters thickness at the surface.

characterisation, phylogenetic analysis,functional annotation

Indian Academy of Sciences (India)

Navya

2017-01-06

Jan 6, 2017 ... 3Collaborative Innovation Center for Efficient and Health Production of ... qPCR: a) in five tissues from a healthy blunt snout bream, indicating ..... FAO (Food and Agriculture Organization of the United Nations) ... Sci.28, 210-214. .... Zhang F., Zhang L., Sun L.-L., Meng X.-L., Zhao Y. and Jin X. 2013 Effects of ...

Nord Stream : täidame kõik Eesti nõudmised / Matthias Warnig ; interv. Jan Jõgis-Laats

Index Scriptorium Estoniae

Warnig, Matthias

2007-01-01

Nord Streami tegevdirektor pakub võimalust, et Eesti esindajad viibiksid gaasitrassi uuringutel, samuti võivad esindajad teha ette teatamata reide. Firma on valmis arutama kõike, mis on vajalik protsessi kontrollimiseks ja usalduse tekitamiseks

Geographic List of Prime Contract Awards. Oct 92-Sep 93. FY 93. (Amos, Kentucky-Montgomery County, Maryland). Part 6

Science.gov (United States)

1994-03-01

r 11 c I0-eJI C1 31 00000P0) 0 (icc C) Cr) M 0 W( D(DE DW D0)o I o0)0 II.’I1)cc jinI 11 ) C\\LC\\m NA NI C111 Mr (’*4 Y MCJMMMMM (nr (YiC ) (ici MCici...0 00 0 0 III0-Ic14򒰌 OW 000 00 00 000 00 00 000> 00 0 00 11 1 l-4N II 1 N N, NN N 4 N NNN > II 10-i- 11 >- z co11111 - I\\ jINI ,-t 0 11 N N 00 Nc 4ɚ...I 0011C U.L 11 c I caoc II 00 11 E I Gao 0r, 1 -- -I .- ---- -- - - - - - - -- ----- 114- I COLD4l II 000000000000000000000000000000000000000000 00 1

[Buddhist influences on Sun Simiao's precious prescriptions for emergency].

Science.gov (United States)

Zhu, J

1999-10-01

Living in a period when the Buddhism was quite flourishing, Sun had a close contact with the monk Dao Xuan, the founder of Nanshan Sect Buddhism. Sun's Quian jin fang adopted all schools including Buddhism, evidenced by the following 3 aspects: 1) Direct Buddhist influence, mainly on medical morality; 2) Indian medicine coming together with Buddhism, including the theory of "four - element theory", the conception of all matters are medicines, pills of all disorders, recipes, and keep - fit art. Buddhism acts as a carrier here; 3) the achievements of treatment for beriberi by monks. However, Buddhist influence was far inferior to Taoism as far as Sun's work is concerned.

Stemmernes politik i samtidskunsten

DEFF Research Database (Denmark)

Hasse, Stina

2016-01-01

In the artworks Emigrant (2013) by Niels Pugholm, Nanna Lysholt Hansen's Miss no.1,2,3 (2013) and The Woman, the Orphan, and the Tiger (2010) by Jane Jin Kaisen og Guston Sondin-Kung, the voice as an artistic medium is used to create a dialogue between the artwork and the listener. It is a dialogue...... that concerns questions of identity politics, but in ways that point at the political systems and social problems that exist on a global and national level. In this article the artworks are discussed in in an effort to understand what role voice plays in the Danish contemporary art today....

Effects of Post-harvest Storage Duration and Variety on Nutrient Digestibility and Energy Content Wheat in Finishing Pigs.

Science.gov (United States)

Guo, P P; Li, P L; Li, Z C; Stein, H H; Liu, L; Xia, T; Yang, Y Y; Ma, Y X

2015-10-01

This study was conducted to investigate the effects of post-harvest storage duration and wheat variety on the digestibility and energy content of new season wheat fed to finishing pigs. Two wheat varieties (Shi and Zhong) were harvested in 2013 and stored in the warehouse of the Fengning Pig Experimental Base at China Agricultural University for 3, 6, 9, or 12 mo. For each storage period, 12 barrows were placed in metabolism crates and allotted to diets containing 1 of the 2 wheat varieties in a randomized complete block design. The experimental diets contained 97.34% wheat and 2.66% of a vitamin and trace mineral premix. With an extension of storage duration from 3 mo to 12 mo, the gross energy (GE) and crude protein (CP) of the wheat decreased by 2.0% and 12.01%, respectively, while the concentration of neutral detergent fiber (NDF), acid detergent fiber (ADF) and starch content increased by 30.26%, 19.08%, and 2.46%, respectively. Total non-starch polysaccharide, total arabinose, total xylose and total mannose contents decreased by 46.27%, 45.80%, 41.71%, and 75.66%, respectively. However, there were no significant differences in the chemical composition between the two wheat varieties with the exception of ADF which was approximately 13.37% lower in Shi. With an extension of storage duration from 3 mo to 12 mo, the digestible energy (DE), metabolizable energy (ME) content and the apparent total tract digestibility of GE, CP, dry matter, organic matter, ether extract, ADF and metabolizability of energy in wheat decreased linearly (pdigestibility of NDF changed quadratically (pdigestibility (pdigestibility of variety Zhong was stable during 9 mo of storage, while the CP digestibility of variety Shi decreased (p<0.05). In conclusion, the GE, DE, and ME of wheat was stable during the first 3 to 6 mo of post-harvest storage, and decreased during the following 6 to 12 mo of storage under the conditions of this study.

Phenomenological theory of size effects in ultrafine ferroelectric particles (PbTiO3-type)

International Nuclear Information System (INIS)

Jiang, B.; Bursill, L.A.

1998-01-01

A new phenomenological model is proposed and discussed to study the size effects on phase transitions in PbTiO 3 -type ferroelectric particles. This model, by taking size effects on the phenomenological Landau-Ginzburg-Devonshire coefficients into consideration, can successfully explain the size effects on Curie temperature, c/a ratio, thermal and dielectric properties of lead-titanate-type ferroelectric particles. Theoretical and experimental results for PbTiO 3 fine particles are also compared and discussed. The relationship between the current model and the model of Zhong et al (Phys. Rev. B 50, 698 (1994)) is also presented. (authors)

Cooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia

Directory of Open Access Journals (Sweden)

Wu X

2017-10-01

Full Text Available Xiaoyan Wu,1 Lin Wang,1 Yining Qiu,1 Bingyu Zhang,1 Zhenhua Hu,2 Runming Jin1 1Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 2Department of Pharmacy, Shanghai Jiao Tong University, Shanghai, China Abstract: T cell acute lymphoblastic leukemia (T-ALL is caused by clonal expansion of variant T cell progenitors and is considered as a high risk leukemia. Contemporary single chemotherapy has a limited effect due to dynamic and versatile properties of T-ALL. Here IRAK1/4 inhibitor and ABT-737 were co-encapsulated into polyethylene glycol modified poly (lactic-co-glycolic acid nanoparticles (IRAK/ABT-NP to enhance synergistic therapy of T-ALL. The formulation was optimized to achieve high drug loading using Box-Behnken design and response surface methodology. The optimal parameter comprised 2.98% polymer in acetonitrile, a ratio of oil phase to water phase of 1:8.33, and 2.12% emulsifier concentration. High drug loading and uniform spherical shape was achieved. In vitro release study showed sustained release of IRAK1/4 inhibitor for 72 hours as well as sustained release of ABT-737 for more than 120 hours. Uptake efficiency of IRAK/ABT-NP and induced apoptotic T-ALL fraction by IRAK/ABT-NP were much higher than the IRAK1/4 and ABT-737 combined solution. IC50 of IRAK/ABT-NP was two-fold lower than free drug combination in Jurkat cells. Additionally, we conducted in vivo experiments in which IRAK/ABT-NP exhibited greater cytotoxicity toward T-ALL cells, the capacity to significantly restore white blood cell number in peripheral blood, and improved survival time of T-ALL mouse model compared to the IRAK1/4 and ABT-737 combined solution. Keywords: T cell acute lymphoblastic leukemia, IRAK1/4 inhibitor, ABT-737, Box-Behnken design and response surface methodology, PEG-PLGA

Pro-lipogenic Action of Lysophosphatidic Acid in Ovarian Cancer

Science.gov (United States)

2014-04-01

Function. IUBMB Life. 2008. 60: 347-354. 11. Tse C, Shoemaker AR, Adickes J, Anderson MG, Chen J, Jin S, Johnson EF, Marsh KC , Mitten MJ, Nimmer P...Ann. Oncol. 9, 437–442 14. Choi, J. W., Herr, D. R., Noguchi, K., Yung, Y. C., Lee, C. W., Mutoh, T., Lin, M. E., Teo , S. T., Park, K. E., Mosley, A

Abstracts from the 15th International Myopia Conference

Directory of Open Access Journals (Sweden)

Alexandra Benavente-Perez

2016-11-01

Full Text Available Table of contents O1 Changes in peripheral refraction associated with decreased ocular axial growth rate in marmosets Alexandra Benavente-Perez, Ann Nour, Tobin Ansel, Kathleen Abarr, Luying Yan, Keisha Roden, David Troilo O2 PPARα activation suppresses myopia development by increasing scleral collagen synthesis--a new drug target to suppress myopia development Chanyi Lu, Miaozhen Pan, Min Zheng, Jia Qu, Xiangtian Zhou O3 Evidence and possibilities for local ocular growth regulating signal pathways Christine F Wildsoet O4 Myopia researches at Eye Hospital of Wenzhou Medical University Fan Lu, Xiangtian Zhou, Jie Chen, Jinhua Bao, Liang Hu, Qinmei Wang, Zibing Jin, Jia Qu O5 Color, temporal contrast and myopia Frances Rucker, Stephanie Britton, Stephan Hanowsky, Molly Spatcher O6 The impact of atropine usage on visual function and reading performance in myopic school children in Taiwan Hui-Ying Kuo, Ching-Hsiu Ke, I-Hsin Kuo, Chien-Chun Peng, Han-Yin Sun O7 Increased time outdoors prevents the onset of myopia: evidence from randomised clinical trials Ian G Morgan O8 Environmental risk factors and gene-environment interactions for myopia in the ALSPAC cohort Jeremy A. Guggenheim, Rupal L. Shah, Cathy Williams O9 Retinal metabolic profiling identifies declines in FP receptor-linked signaling as contributors to form-deprived myopic development in guinea pigs Jinglei Yang, Peter S. Reinach, Sen Zhang, Miaozhen Pan, Wenfeng Sun, Bo Liu, Xiangtian Zhou O10 The study of peripheral refraction in moderate and high myopes after one month of wearing orthokeratology lens Jun Jiang, Haoran Wu, Fan Lu O11 Axial length of school children around the earth’s equatorial area and factors affecting the axial length Kazuo Tsubota, Hiroko Ozawa, Hidemasa Torii, Shigemasa Takamizawa, Toshihide Kurihara, Kazuno Negishi O12 Processing of defocus in the chicken retina by retinal ganglion cells Klaus Graef, Daniel Rathbun, Frank Schaeffel O13 Blue SAD light protects

Properties of power series of analytic in a bidisc functions of bounded $\\mathbf{L}$-index in joint variables

Directory of Open Access Journals (Sweden)

A. I. Bandura

2017-07-01

Full Text Available We generalized some criteria of boundedness of $\\mathbf{L}$-index in joint variables for analytic in a bidisc functions, where $\\mathbf{L}(z=(l_1(z_1,z_2,$ $l_{2}(z_1,z_2,$ $l_j:\\mathbb{D}^2\\to \\mathbb{R}_+$ is a continuous function, $j\\in\\{1,2\\},$ $\\mathbb{D}^2$ is a bidisc $\\{(z_1,z_2\\in\\mathbb{C}^2: |z_1|<1,|z_2|<1\\}.$ The propositions describe a behaviour of power series expansion on a skeleton of a bidisc. We estimated power series expansion by a dominating homogeneous polynomial with the degree that does not exceed some number depending only from radii of bidisc. Replacing universal quantifier by existential quantifier for radii of bidisc, we also proved sufficient conditions of boundedness of $\\mathbf{L}$-index in joint variables for analytic functions which are weaker than necessary conditions.

A bibliometric analysis of the 100 most influential papers on COPD

Directory of Open Access Journals (Sweden)

Gu WC

2015-03-01

Full Text Available Wenchao Gu,1 Yaping Yuan,1  Hua Yang,1 Guangsheng Qi,1 Xiaoyan Jin,2 Jin Yan2 1Department of Respiratory Medicine, People’s Hospital of Shanghai, Pudong New Area, 2Department of Respiratory Medicine, Tongren Hospital, Shanghai, People’s Republic of China Objective: We aimed to identify the 100 top-cited articles published on chronic obstructive pulmonary disease (COPD and to analyze their characteristics so as to provide information on the achievement and development in COPD research over the past decades. Methods and materials: A comprehensive list of citation classics in COPD was generated by searching the Science Citation Index expanded database, using the keywords “COPD” or “chronic obstructive pulmonary disease” or “chronic obstructive pulmonary diseases”. The 100 top-cited research papers were retrieved by reading the abstract or full text if needed. All eligible articles were read for basic information, including country of origin, organizations, article type, journals, research field, and authors.Results: The 100 top-cited articles on COPD were published between 1966 and 2010. The number of citations ranged from 254 to 2,164, with a mean of 450 citations for each article. These citation classics were from 32 countries, with 38 from the United States. The Imperial College London led the list of classics, with 16 papers. The 100 top-cited articles were distributed in 18 journals, with the American Journal of Respiratory, Critical Care Medicine, and Journal of the American Medical Association topping the list. Among the various fields, both respiratory system (63% and general internal medicine (63% were the most common fields of study for the 100 articles. Conclusion: Our bibliometric analysis provides a historical perspective on the progress of scientific research on COPD. Articles originating from the United States and published in high-impact specialized respiratory journals are most likely to be cited in the

Presence of sarcopenia in asthma–COPD overlap syndrome may be a risk factor for decreased bone-mineral density, unlike asthma: Korean National Health and Nutrition Examination Survey (KNHANES IV and V (2008–2011

Directory of Open Access Journals (Sweden)

Lee DW

2017-08-01

Full Text Available Dong-Won Lee,1 Hyun-Jung Jin,2 Kyeong-Cheol Shin,2 Jin-Hong Chung,2 Hyoung-Woo Lee,3 Kwan-Ho Lee2 1Division of Pulmonology, Department of Internal Medicine, Andong Sungso Hospital, Andong, 2Division of Pulmonology and Allergy, 3Division of Endocrinology, Department of Internal Medicine, Yeungnam University Hospital, Daegu, South Korea Background: Sarcopenia and decreased bone-mineral density (BMD are common in elderly people, and are major comorbidities of obstructive airway disease (OAD. However, the relationship between sarcopenia and BMD in each OAD phenotype, especially asthma–COPD overlap syndrome (ACOS, is not yet clear. We aimed to evaluate differences in BMD according to the presence of sarcopenia in each OAD phenotype. Materials and methods: Among the research subjects in KNHANES IV and V (2008–2011, 5,562 were ≥50 years old and underwent qualified spirometry and dual-energy X-ray absorptiometry. A total of 947 subjects were included in the study: 89 had asthma, 748 COPD, and 110 ACOS. Results: In the COPD and ACOS phenotypes, T-scores were lower in the sarcopenia group than the nonsarcopenia group. Prevalence rates of osteopenia and osteoporosis were higher in the sarcopenia group than the nonsarcopenia group. (P<0.001 and P=0.017, respectively. The sarcopenia group had higher risks of developing osteopenia, osteoporosis, and low BMD than the nonsarcopenia group in the ACOS phenotype (OR 6.620, 95% CI 1.129–38.828 [P=0.036], OR 9.611, 95% CI 1.133–81.544 [P=0.038], and OR 6.935, 95% CI 1.194–40.272 [P=0.031], respectively. However, in the asthma phenotype, the sarcopenia group showed no increased risk compared with the nonsarcopenia group. Conclusion: In the ACOS phenotype, individuals with sarcopenia had a higher prevalence rate and higher risks of osteopenia and osteoporosis than those without sarcopenia among all OAD phenotypes. Keywords: asthma, chronic obstructive pulmonary disease, asthma–COPD overlap syndrome

Teleradiology (TELEACE) system: results of a field trial

International Nuclear Information System (INIS)

Lee, Jong Min; Kim, Gi Bum; Seong, Yeung Soon; Suh, Kyung Jin; Kang, Duk Sik

1993-01-01

We report the results of field operation of TELEACE system between Kyung-Pook National University Hospital and Ul-Jin Goon Health Care Medical Center from December, 1990 to September, 1991, which had been operated as a kind of Integrated Services Digital Network projects by KOREA TELECOMMUNICATION Inc. Ul-Jin Goon Health Care Medical Center transmitted 414 plain radiographs to our hospital in speed of 9600BPS. Each image was composed of 1024X1024 pixelsX8 bits/pixel. In our hospital, the image flies were displayed on high resolution monitor (1280X1024 pixels). Text files of image interpretations were transmitted to the health care medical center. The two radiologists who had interpreted the transmitted images, went to the health care medical center and read radiographic films with blind test method. We obtained the following results: false negative rate of 6.3%, false positive rate of 2.4%, mean sensitivity of 81.4%, mean specificity of 96.3%, and mean accuracy of 91.3%. In predictive value of 0.05, there was no significant difference between results of these two types of radiographs. In conclusion, TELEACE system was valuable to the clinicians isolated from services of radiologists

Álevité – jiné pojetí islámu?

Directory of Open Access Journals (Sweden)

Kateřina Vytejčková

2012-04-01

Full Text Available The Alevi are a religious minority in Turkey. It is a heterogeneous group including millions of Muslims who do not profess the major Sunni movement. During the time of the Ottoman Empire they were often persecuted as heretics. The Alevi and the Bektashi rise from the same origins which stretch back to the 13century to the theory of dervish Hadji Bektash Veli. In the first case it was concerned mainly rural inhabitants and in the second case it was concerned urban inhabitants – members and adherents of the dervish order Bektashi. Alevi Islam is called “Folk Islam”. It connects the elements of Shi’a Islam, Sufi movement, Christianity and pre- Islam systems of belief. The Alevi are despised by the major society because they do not stand aloof from drinking alcohol and they do not keep the Five Pillars of Islam which the orthodox Islam is based on. There was created a separate genre of anecdotes about the Alevi-Bektashi. This contribution introduces the main principles of their belief and ceremonies and brings also illustrations of some anecdotes.

77 FR 35021 - Kwan Bo Jin, M.D.; Decision and Order

Science.gov (United States)

2012-06-12

...] DEA registration is not appropriate.'' Anibal P. Herrera, M.D., 61 FR 65,075, 65,078 (DEA 1996); see... ``there were serious questions as to the integrity of the registrant.'' Anibal P. Herrera, M.D., 61 FR 65...

New opinion on the subtypes of poststroke depression in Chinese stroke survivors

Directory of Open Access Journals (Sweden)

Yue Y

2017-03-01

Full Text Available Yingying Yue,1,2 Rui Liu,3 Yin Cao,4 Yanfeng Wu,5 Shining Zhang,6 Huajie Li,7 Jijun Zhu,8 Wenhao Jiang,1,2 Aiqin Wu,9 Yonggui Yuan1,2 1Department of Psychosomatics and Psychiatry, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, 2Institute of Psychosomatics, Medical school of Southeast university, Nanjing, 3School of Information Science and Engineering, Southeast University, Nanjing, 4Department of Neurology, Changzhou Second People’s Hospital Affiliated to Nanjing Medical University, Changzhou, 5Department of Neurology, The Second Affiliated Hospital of Nanjing Medical University, 6Department of Psychiatry, Nanjing Brain Hospital of Nanjing Medical University, Nanjing, 7Department of Neurology, Changzhou First People’s Hospital, Changzhou, 8Department of Neurology, Yancheng Third People’s Hospital, Yancheng, 9Department of Psychosomatics, The Affiliated First Hospital of Suzhou University, Suzhou, People’s Republic of China Aim: Poststroke depression (PSD is the most common complication of stroke. However, some stroke survivors with depression cannot meet the diagnostic criteria of PSD. The aim of this study was to propose the new conception of stroke patients with depression and then make them to receive reasonable diagnosis and treatment. Methods: We first put forward the opinion that the general PSD should consist of PSD disorder (PSDD and PSD symptoms (PSDS according to the Diagnostic and Statistical Manual of Mental Disorder – Fifth Edition (DSM-5 and ZhongDa diagnostic criteria – first edition (ZD-1, respectively. The ZD-1 was established based on the suggestions of 65 Chinese chief doctors considering that the symptoms of PSDS might be different from those of PSDD and the duration of DSM-5 was too strict. Then, 166 stroke inpatients were recruited, and the study was conducted using the diagnosis and classification of PSD to verify the new concept. Results: A total of 24 (14.46% and 80 (48.19% stroke

The clinical significances of the abnormal expressions of Piwil1 and Piwil2 in colonic adenoma and adenocarcinoma

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Wang HL

2015-05-01

Full Text Available Hai-Ling Wang,1 Bei-Bei Chen,1 Xin-Guang Cao,1 Jin Wang,2 Xiu-Feng Hu,1 Xiao-Qian Mu,1 Xiao-Bing Chen1 1The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, People’s Republic of China; 2The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China Objective: The objective of the present investigation was to study the clinical significances of the abnormal expressions of Piwil1 and Piwil2 protein in colonic adenoma and adenocarcinoma.Methods: This study had applied immunohistochemical method to detect 45 cases of tissues adjacent to carcinoma (distance to cancerous tissue was above 5 cm, 41 cases of colonic adenoma and 92 cases of colon cancer tissues, and their Piwil1 and Piwil2 protein expression levels.Analysis: The correlation of both expression and its relationship with clinicopathological features of colon cancer was analyzed.Results: Positive expression rates of Piwil1 in tissues adjacent to carcinoma, colonic adenoma, and colon cancer were 11.1% (5/45, 53.7% (22/41, and 80.4% (74/92, respectively; the expression rates increased, and the comparisons between each two groups were statistically significant (P<0.05. In each group, the positive expression rates of Piwil2 were 24.4% (11/45 cases, 75.6% (31/41 cases, and 92.4% (85/92 cases; expression rates increased, and the comparisons between each two groups were statistically significant (P<0.05. Piwil1 expression and the correlation of the degree of differentiation, TNM stage, and lymph node metastasis were statistically significant (P<0.05. Piwil2 expression and the correlation of the degree of differentiation, tumor node metastasis (TNM stage, and lymph node metastasis had no statistical significance (P>0.05. In colon cancer tissue, Piwil1 and Piwil2 expressions were positively correlated (r=0.262, P<0.05.Conclusion: The results showed that the abnormal expression of Piwil1 and Piwil2 might play an important role in

Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis

OpenAIRE

Li ZN; Jin ZH

2016-01-01

Zhouna Li, Zhehu Jin Department of Dermatology, Yanbian University Affiliated hospital, Yanji, Jilin, People’s Republic of China Background: Keloids and hypertrophic scars are the most common types of pathological scarring. Traditionally, keloids have been considered as a result of aberrant wound healing, involving excessive fibroblast participation that is characterized by hyalinized collagen bundles. However, the usefulness of this characterization has been questioned. In recent yea...

Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis

OpenAIRE

Li,Zhouna; Jin,Zhehu

2016-01-01

Zhouna Li, Zhehu Jin Department of Dermatology, Yanbian University Affiliated hospital, Yanji, Jilin, People’s Republic of China Background: Keloids and hypertrophic scars are the most common types of pathological scarring. Traditionally, keloids have been considered as a result of aberrant wound healing, involving excessive fibroblast participation that is characterized by hyalinized collagen bundles. However, the usefulness of this characterization has been questioned. In recent...

Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy

OpenAIRE

Han, Jae Woong; Gurunathan, Sangiliyandi; Choi, Yun-Jung; Kim, Jin-Hoi

2017-01-01

Jae Woong Han, Sangiliyandi Gurunathan, Yun-Jung Choi, Jin-Hoi Kim Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Center (SRC), Konkuk University, Seoul, Republic of Korea Background: Silver nanoparticles (AgNPs) exhibit strong antibacterial and anticancer activity owing to their large surface-to-volume ratios and crystallographic surface structure. Owing to their various applications, understanding the mechanisms of action, biological interactions, potential...

Modal Theory of Transverse Acoustic Coherence in Shallow Oceans

Science.gov (United States)

2012-09-28

J. Ocean. Eng. 24(3), 333–345 (1999). 54. J. F. Lynch, G. Jin, R. Pawlowicz, D. Ray, A. J. Plueddenmann, C.-S. Chiu, J. H. Miller, R. H. Bourke , A. R...Theory and experiment,” J. Acoust. Soc. Am. 99(2), 803–821 (1996). 55. A. R. Parsons, R. H. Bourke , R. D. Muench, C.-S. Chiu, J. F. Lynch, J. H. Miller

Characterization and remediation of Soil Contaminated with Explosives: Development of Practical Technologies

Science.gov (United States)

2001-07-06

typically used as a surfactant allowing an increased pollutant bioavailability in various bioremediation treatment processes. In the particular case... Bioremediation f. 2000, 4, 27-39. (25) Hawari, J.In Biodegradation ofNitroaromatic Compounds and Explosives; Spain, J. C., Hughes, J. B., Knackmuss, H.-J...terrestrial plants such as sunflower and sanfroin. Significant sublethal effects of RDX were observed on the reproduction of earthworm Eisenia

The association between osteopontin and survival in non-small-cell lung cancer patients: a meta-analysis of 13 cohorts

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Wang Y

2015-11-01

Full Text Available Ying Wang,1,* Jin Yang,1,* Hui Liu,1 Ji-Rui Bi,1 Ying Liu,2 Yan-Yan Chen,2 Ji-Yu Cao,2 You-Jin Lu1 1Department of Respiratory Medicine, the Second Affiliated Hospital of Anhui Medical University, 2Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, People’s Republic of China *These authors contributed equally to this work Abstract: In the last decade, osteopontin (OPN was identified as one of the important proteins that promote the metastasis of tumor. However, the association between OPN overexpression and clinical outcome of non-small-cell lung cancer (NSCLC was unclear. The purpose of this study is to investigate the role of OPN in NSCLC patients. A total of 13 studies are included to explore the relationship between the OPN elevation and the overall survival (OS and disease-free survival (DFS in NSCLC patients. We searched for related articles in PubMed, Web of Science, Google Scholar, and Cochrane Library databases, which were published before January 31, 2015. Hazard ratio (HR, odds ratio (OR, and 95% confidence interval (CI in the high OPN expression group compared with the low OPN expression group were calculated and analyzed. Primary results were summarized by using a fixed-effects model or a random-effects model. The stratified analyses in subgroups were also performed. Thirteen cohort studies, which involved 1,630 patients, were included. Subgroup analyses were performed by area and test method of OPN. We found that OPN was significantly associated with poor OS (HR =2.20, 95% CI 1.71–2.83, P<0.001 and DFS (HR =2.11, 95% CI 1.62–2.74, P<0.001 in NSCLC patients. OPN overexpression tended to be associated with the presence of advanced tumor TNM stage (III and IV (OR =2.57, 95% CI 1.61–4.11, P<0.001. The Egger’s test suggested that there was no publication bias in OS studies (P=0.062 and DFS studies (P=0.740. These data indicate that OPN seems to have a

Recovery of a 10-year-old girl from methicillin-resistant Staphylococcus aureus sepsis in response to low-dose ceftaroline treatment

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Borgmann S

2016-05-01

Full Text Available Stefan Borgmann,1 Beate Rieß,1 Thomas von Wernitz-Keibel,2 Matthias Bühler,3 Franziska Layer,4 Birgit Strommenger4 1Department of Infectious Diseases and Infection Control, 2Department of Anaesthesiology and Intensive Care Medicine, 3Department of Trauma Surgery, Klinikum Ingolstadt, Ingolstadt, 4National Reference Centre for Staphylococci and Enterococci, Division Nosocomial Pathogens and Antibiotic Resistances, Department for Infectious Diseases, Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany Abstract: A 9-year-old girl was severely injured in a car accident in Afghanistan, in which both her lower legs were badly damaged. She was treated at the Hospital of Ingolstadt (Klinikum Ingolstadt after she had undergone initial surgery at an Indian hospital. Various bacterial species were isolated from multiple wounds, and methicillin-resistant Staphylococcus aureus (MRSA was one among them. After the amputation of her lower legs, she developed MRSA sepsis, which was successfully treated with a relatively low dosage of ceftaroline (Zinforo®/Teflaro®; 2×9 mg/kg/d, although the bacterial isolate’s minimal inhibitory concentration (1.5–4 mg/L suggested a decreased susceptibility. In summary, ceftaroline was highly efficient and well tolerated by the patient suffering from MRSA sepsis. Keywords: side effects, susceptibility, ceftaroline, minimal inhibitory concentration, therapy 

Evolution of new superconductors. Past, present and future

International Nuclear Information System (INIS)

Akimitsu, Jun

2011-01-01

I present here the past and present situations of new superconductors and also the future prospect. Superconductivity has started since Kamerlingh Onnes first observed the zero resistivity. After that, the critical temperature T c was gradually increased. In the early stage of superconductive material investigations, main contribution has been made by B. Matthias and his group. In 1986, a new superconductor La-Ba-Cu-O, which belongs to new category in the superconducting society, has been found by Bednorz and Mueller. After that T c 's have been drastically increased, and finally reached to T c - 164 K in the Hg-compound. Next, I review several new superconductors discovered within 20 years. Finally, I mention my personal perspective to a high-T c superconductor. (author)

Enhancing undergraduate students’ communications skills

DEFF Research Database (Denmark)

Jørgensen, Merete; Witt, Klaus; Fridorff-Jens, Peter Kindt

2014-01-01

,Monika Bullinger,Matthias Rose, Sylke Andreas.Enhancing medical students' communication skills: development and evaluation of an undergraduate training program.Published online 2012 March 24. doi: 10.1186/1472-6920-12-16 2.William T. Branch, Jr, MD; David Kern, MD; Paul Haidet, MD, MPH; Peter Weissmann, MD......19729 Abstract Title: Enhancing undergraduate students communications skills Abstract Authors: •Merete Jorgensen, Copenhagen University , Family Medicine , Copenhagen •Klaus Witt, Research Unit , Family Medicine , Copenhagen •Peter Kindt Fridorff-Jens, Copenhagen University , IT-unit , Copenhagen...... Abstract Presenter(s): •Merete Jorgensen, Copenhagen University , Family Medicine , Øster Farigmagsgade 5 , 1014 , K , Denmark , mejor@sund.ku.dk Abstract: Background Being teachers in Clinical Course of Family Medicine since 1995, we have developed two schemes for communication analysing purposes called...

Neuroleptic malignant syndrome and subsequent clozapine-withdrawal effects in a patient with refractory schizophrenia

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Cheng MF

2016-03-01

Full Text Available Minfeng Cheng,* Huaying Gu,* Liangrong Zheng, Houliang Wang, Zhiyong Zhong, Shenglin Wen Department of Psychiatry, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Here, we report a female patient developing neuroleptic malignant syndrome following the use of a combination of clozapine and haloperidol. Subsequently, the patient presented withdrawal effects after an abrupt discontinuation of clozapine. Psychiatrists not aware of possible clozapine-withdrawal effects may misdiagnose as a part of the primary mental illness or as the initial symptoms worsening, if unrecognized. Keywords: clozapine, neuroleptic malignant syndrome, withdrawal effect, schizophrenia

Static lung volume should be used to confirm restrictive lung disease

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Rasam SA

2016-09-01

Full Text Available Shweta A Rasam, Nitin V Vanjare Department of Pulmonary Function Laboratory, Chest Research Foundation, Pune, Maharashtra, IndiaWe read the study by Hee Jin Park et al1 with great interest. The authors have investigated the prevalence of comorbidities in Korean chronic obstructive pulmonary disease (COPD population. We raise our concern regarding the definition of COPD in this study. The study defines COPD as airflow limitation (only pre-spirometry forced expiratory volume in 1 second/forced vital capacity [FEV1/FVC] <70% in subjects aged ≥40 years. To differentiate, between asthma and COPD, it is essential to do a post bronchodilator spirometry. It would have been wise to report the findings as prevalence of comorbidities in obstructive airway diseases rather than specifically calling it as COPD.View original paper by Park and colleagues.

Dam break analysis and flood inundation map of Krisak dam for emergency action plan

Science.gov (United States)

Juliastuti, Setyandito, Oki

2017-11-01

The Indonesian Regulation which refers to the ICOLD Regulation (International Committee on Large Dam required have the Emergency Action Plan (EAP) guidelines because of the dams have potential failure. In EAP guidelines there is a management of evacuation where the determination of the inundation map based on flood modeling. The purpose of the EAP is to minimize the risk of loss of life and property in downstream which caused by dam failure. This paper will describe about develop flood modeling and inundation map in Krisak dam using numerical methods through dam break analysis (DBA) using hydraulic model Zhong Xing HY-21. The approaches of dam failure simulation are overtopping and piping. Overtopping simulation based on quadrangular, triangular and trapezium fracture. Piping simulation based on cracks of orifice. Using results of DBA, hazard classification of Krisak dam is very high. The nearest village affected dam failure is Singodutan village (distance is 1.45 kilometer from dam) with inundation depth is 1.85 meter. This result can be used by stakeholders such as emergency responders and the community at risk in formulating evacuation procedure.

Image Feature Detection and Matching in Underwater Conditions

Science.gov (United States)

2010-04-01

and ||jlr< li "-Hjj3 < l l=1’-’N „ (17) 0 if k 7^ argmin||r’ — s||2 or k = argmin||r’ - s||2 and Jin.) ’K. > t i=l N i=l N l|r Ŗ matchRNN(fl...Affix (v*01)[F-0_3 O He-un Affine (V Mil 1 F -0M •’ li •« \\irii« a,, lit i I 0-25 (a) SIFT with Nearest Neighbor Matching (b) GLOH...F - 0 𔄁 • Htm* I «pl.ee It. 3 0) | F - 0 17 -*-Hini»-L«(itaM (({,- 10)|F-0.I - He- Mian [ «place <V (I II I 0 < & He-un-Laplace (Z- 3 0

Overexpression of high mobility group box 1 contributes to progressive clinicopathological features and poor prognosis of human bladder urothelial carcinoma

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Huang CK

2018-04-01

Full Text Available Changkun Huang,* Zhichao Huang,* Xiaokun Zhao, Yinhuai Wang, Hongqing Zhao, Zhaohui Zhong, Lang Wang Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China *These authors contributed equally to this work Background: High mobility group box 1 (HMGB1, a versatile protein with intranuclear and extracellular functions, plays an important role in a variety of human cancers. However, the clinical/prognostic significance of HMGB1 expression in human bladder urothelial carcinoma (BUC remains unclear. The aim of this study was to investigate the HMGB1 expression in human BUC with regard to its clinical and prognostic significance.Patients and methods: HMGB1 mRNA and protein expressions in tumor and paired normal bladder tissues were detected in 20 BUC cases by quantitative real-time polymerase chain reaction (qRT-PCR and Western blot. HMGB1 protein expression in 165 primary BUC tissues was evaluated by immunohistochemistry (IHC, and its correlations with clinicopathological characteristics and prognosis were also analyzed. Student’s t-test, χ2 test, Kaplan–Meier plots, and Cox proportional hazard regression model were performed to analyze the data. Results: By using qRT-PCR and Western blot, the upregulated expression of HMGB1 mRNA and protein was detected in BUC, compared with paired normal tissue (P<0.05. By using IHC, high HMGB1 expression was examined in 84 of 165 (51.0% BUC cases. High HMGB1 expression was significantly correlated with poorer differentiation and higher T and N classification (all P<0.05. Univariate analysis showed that high HMGB1 expression was significantly associated with a shortened patients’ overall survival (OS and disease-free survival (DFS; both P<0.001. In different subgroups of BUC patients, HMGB1 expression was a prognostic factor in patients with different histological grades or T classification (all P<0.05, pN− (both P<0.001 for OS and DFS, and

2nd Rochester Conference on Superconductivity in D- and F- Band Metals

CERN Document Server

Superconductivity in d- and f- band metals

1976-01-01

The occurrence of superconductivity among the d- and f-band metals remains one of the unsolved problems of physics. The first Rochester conference on this subject in October 1971 brought together approximately 100 experimentalists and theorists, and that conference was considered successful; the published proceedings well-represented the current research at that time and has served as a "handbook" to many. In the four and one half years since the first conference, impressive progress has been made in many areas (although Berndt Matthias would be one of the first to point out that raising the m"aximum transition temperature by a significant amount was not one of them). For a variety of reasons, I decided that it was time for a Second Rochester Conference on Superconductivity in d- and f-Band Metals and it was held on April 30 and May 1, 1976. It would appear that this conference was even more successful judging from the quality of the talks and various comments made to me. I believe that this was due...

Helicopter Flying Qualities Characteristics-CH-46E. Volume 4.

Science.gov (United States)

1983-10-03

In UC in., WP.. o"N 05% w 0 ILw60V U.UNt’- =0 GAO 4 NCw-I W%?qWee -I.al OMMM aZ1. Z1 I- -- 4 >m Enl MwCe 0 0 40-1 m60’ Now"’%6 MMMM 60 41 .0 T in g n...1- %-r U. LL 4N WWN= ILL w e40 U.ww =I imn kn = %. E ’a 4C4 M N CD 0%r %r NN N % C C 0..6. * W x Xi W N X.&ON a0.. JinI ON ..1.-AV".-4 ww0-. M’ W...I="Iv K~~ I I1II . 4 ..a.a~a gao ma Qi co 0MMO =4Mp~~ &Ww Wa. 0P ~w ":m II mme Od a - amaac c44 c44 0 1% CY an-$ U.s .. r (M " ty U**@@**~ ~ ~ a

Oxidative stress-mediated antibacterial activity of graphene oxide and reduced graphene oxide in Pseudomonas aeruginosa

OpenAIRE

Gurunathan, Sangiliyandi; Han,Jae Woong; Abdal Daye,Ahmed; Eppakayala,Vasuki; Kim,Jin-Hoi

2012-01-01

Sangiliyandi Gurunathan, Jae Woong Han, Ahmed Abdal Dayem, Vasuki Eppakayala, Jin-Hoi KimDepartment of Animal Biotechnology, Konkuk University, Seoul, South KoreaBackground: Graphene holds great promise for potential use in next-generation electronic and photonic devices due to its unique high carrier mobility, good optical transparency, large surface area, and biocompatibility. The aim of this study was to investigate the antibacterial effects of graphene oxide (GO) and reduced graphene oxid...

TNT Degradation by Natural Microbial Assemblages at Frontal Boundaries Between Water Masses in Coastal Ecosystems (ER-2124)

Science.gov (United States)

2017-06-20

receptor protein) and reduce substrate mineralization depending on how long it would take to disassociate the humic from the substrate upon dilution...geochemical samples . Anal. Chem. 72:3116-3121. Han, L., Sun, K., Jin, J., and B. Xing. 2016. Some concepts of soil organic carbon characteristics and...capacity for energetics released into hydrodynamically similar, UXO-impacted ecosystems where access to site samples may be limited. During samplings in

Sisekujunduse maailmameistrid / Lylian Meister

Index Scriptorium Estoniae

Meister, Lylian, 1966-

2008-01-01

Hollandis 2007. a. novembris esmakordselt toimunud rahvusvahelisest sisearhitektuurikonkursist The Great Indoors Award. Aasta sisekujundusfirmaks valiti Masamichi Katayama asutatud Wonderwall. Ülejäänud auhinnad said Zaha Hadid Hispaanias asuva R.Lopez de Heredia veinidegusteerimise keskuse kujunduse eest, Heatherwick Studio East Beach Cafe kujunduse eest Inglismaal, Ryui Nakamura Architects Jins Global Standard prillipoe kontseptuaalse lahenduse eest Tokyos ja Item Idem Bernhard Willhelmi moebrändi esindusbutiigi kujunduse eest Tokyos

Ultra-Sensitive Biological Detection via Nanoparticle-Based Magnetically Amplified Surface Plasmon Resonance (Mag-SPR) Techniques

Science.gov (United States)

2008-10-08

surfactant such as hexadecyltrimethyl ammonium bromide (CTMA). And also CTMA- polymethacrylic acid (PMA), CTMA-Polyglutamic acid were synthesized as reference...rich world of naturally occurring biomaterials probably none is more important and more fundamental than DNA (deoxyribonucleic acid ), the polymeric...deoxyribonucleic acid gate dielectric," Journal of Applied Physics, vol. 100, p. 024514, 2006. [3] C. H. Lee, E.-D. Do, Y.-W. Kwon, D.-H. Choi, J.-I. Jin

Bayesian Aggregation of Evidence for Detection and Characterization of Patterns in Multiple Noisy Observations

Science.gov (United States)

2015-07-01

Konstantin N Borozdin, Alexei V Klimenko, William C Priedhorsky, Nicolas Hengartner, Charles C Alexander, R Andres Cortez, Herbert G Tanner, and Xanthi... Tan - don, Rob MacLachlan, and Jay Jin. Presentation: Machine learning for effective nuclear search and broad area monitoring. ARI Annual Review, 2014...Distributed Constraints Reasoning (DCR09), at IJCAI, volume 9, 2009. [70] Di Tian and Nicolas D Georganas. A node scheduling scheme for energy

A Multi-Criterion Evolutionary Approach Applied to Phylogenetic Reconstruction

OpenAIRE

Cancino, W.; Delbem, A.C.B.

2010-01-01

In this paper, we proposed an MOEA approach, called PhyloMOEA which solves the phylogenetic inference problem using maximum parsimony and maximum likelihood criteria. The PhyloMOEA's development was motivated by several studies in the literature (Huelsenbeck, 1995; Jin & Nei, 1990; Kuhner & Felsenstein, 1994; Tateno et al., 1994), which point out that various phylogenetic inference methods lead to inconsistent solutions. Techniques using parsimony and likelihood criteria yield to different tr...

Taoistický pohled na trénování ve fotbalu a triatlonu

OpenAIRE

Skála, Tomáš

2009-01-01

Nazev: Taoisticky pohled na trenovani ve fotbalu a triatlonu Cile prace: Objasnit pojmy taoismus a Tao, pomoci jejich charakteristiky osvetlit taoisticke vnimani sebe sama, okolniho sveta a pohybove aktivity, s naslednou aplikaci na konkretni sporty fotbal a triatlon. Metody: Deskripce, analyza, spekulace Klicova slova: Taoismus, Tao, Cchi, Jin a Jang, Wu-Wej, fotbal, triatlon, zacatecnicka mysl SUMMARY Title: The taoistic view in the football and triatlon training Objective: To explain terms...

Periorbital muscle atrophy associated with topical bimatoprost therapy

OpenAIRE

Wang, Priscilla Xinhui; Koh, Victor Teck Chang; Cheng, Jin Fong

2014-01-01

Priscilla Xinhui Wang, Victor Teck Chang Koh, Jin Fong ChengDepartment of Ophthalmology, National University Health System, SingaporeAbstract: Topical Bimatoprost is a common and popular prostaglandin analog used as an ocular hypotensive agent in the treatment of glaucoma. Side effects include ocular hyperaemia, ocular pruritus, and periocular and iris pigmentary changes. Perioribital lipodystrophy is another well-documented outcome associated with chronic use of topical bimatoprost, which re...

Influence of polyethylene glycol coating on biodistribution and toxicity of nanoscale graphene oxide in mice after intravenous injection

Directory of Open Access Journals (Sweden)

Li B

2014-10-01

Full Text Available Bo Li,1,2 Xiao-Yong Zhang,1 Jian-Zhong Yang,1 Yu-Jie Zhang,1 Wen-Xin Li,1 Chun-Hai Fan,1 Qing Huang1 1Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 2Department of Human Anatomy, College of Basic Medical Sciences, Jilin University, Changchun, People’s Republic of China Abstract: In this study, we assessed the in vivo behavior and toxicology of nanoscale graphene oxide (NGO in mice after intravenous injection. The influence of a polyethylene glycol (PEG coating on the distribution and toxicity of the NGO was also investigated. The results show that NGO is mainly retained in the liver, lung, and spleen. Retention in the lung is partially due to NGO aggregation. The PEG coating reduces the retention of NGO in the liver, lung, and spleen and promotes the clearance of NGO from these organs, but NGO and NGO-PEG are still present after 3 months. The PEG coating effectively reduces the early weight loss caused by NGO and alleviates NGO-induced acute tissue injuries, which can include damage to the liver, lung, and kidney, and chronic hepatic and lung fibrosis. Keywords: graphene oxide, biodistribution, toxicity, polyethylene glycol

Lamotrigine blocks NMDA receptor-initiated arachidonic acid signalling in rat brain: Implications for its efficacy in bipolar disorder

Science.gov (United States)

Ramadan, Epolia; Basselin, Mireille; Rao, Jagadeesh S.; Chang, Lisa; Chen, Mei; Ma, Kaizong; Rapoport, Stanley I.

2011-01-01

An upregulated brain arachidonic acid (AA) cascade and a hyperglutamatergic state characterize bipolar disorder (BD). Lamotrigine (LTG), a mood stabilizer approved for treating BD, is reported to interfere with glutamatergic neurotransmission involving N-methyl-D-aspartate receptors (NMDARs). NMDARs allow extracellular calcium into the cell, thereby stimulating calcium-dependent cytosolic phospholipase A2 (cPLA2) to release arachidonic acid (AA) from membrane phospholipid. We hypothesized that LTG, like other approved mood stabilizers, would reduce NMDAR-mediated AA signaling in rat brain. An acute subconvulsant dose of NMDA (25 mg/kg) or saline was administered intraperitoneally to unanesthetized rats that had been treated p.o. daily for 42 days with vehicle or a therapeutically relevant dose of LTG (10 mg/kg/.d). Regional brain AA incorporation coefficients k* and rates Jin, AA signals, were measured using quantitative autoradiography after intravenous [1-14C]AA infusion, as were other AA cascade markers. In chronic vehicle-treated rats, acute NMDA compared to saline increased k* and Jin in widespread regions of the brain, as well as prostaglandin (PG)E2 and thromboxane B2 concentrations. Chronic LTG treatment compared to vehicle reduced brain cyclooxygenase (COX) activity, PGE2 concentration, and DNA binding activity of the COX-2 transcription factor, NF-κB. Pretreatment with chronic LTG blocked the acute NMDA effects on AA cascade markers. In summary, chronic LTG like other mood stabilizers blocks NMDA-mediated signaling involving the AA metabolic cascade. Since markers of the AA cascade and of NMDAR signaling are up-regulated in the postmortem BD brain, mood stabilizers generally may be effective in BD by dampening NMDAR signalling and the AA cascade. PMID:21733229

Oxidative stress by layered double hydroxide nanoparticles via an SFK-JNK and p38-NF-κB signaling pathway mediates induction of interleukin-6 and interleukin-8 in human lung epithelial cells

Directory of Open Access Journals (Sweden)

Choi SJ

2015-04-01

Full Text Available Soo-Jin Choi, Hee-Jeong Paek, Jin YuDepartment of Food Science and Technology, Seoul Women’s University, Seoul, Republic of KoreaAbstract: Anionic nanoclays are layered double hydroxide nanoparticles (LDH-NPs that have been shown to exhibit toxicity by inducing reactive oxidative species and a proinflammatory mediator in human lung epithelial A549 cells. However, the molecular mechanism responsible for this LDH-NP-induced toxicity and the relationship between oxidative stress and inflammatory events remains unclear. In this study, we focused on intracellular signaling pathways and transcription factors induced in response to oxidative stress caused by exposure to LDH-NPs in A549 cells. Mitogen-activated protein kinase (MAPK cascades, such as extracellular signal-regulated kinase, c-Jun-N-terminal kinase (JNK, and p38, were investigated as potential signaling mechanisms responsible for regulation of oxidative stress and cytokine release. Src family kinases (SFKs, which are known to mediate activation of MAPK, together with redox-sensitive transcription factors, including nuclear factor kappa B and nuclear factor-erythroid 2-related factor-2, were also investigated as downstream events of MAPK signaling. The results obtained suggest that LDH-NP exposure causes oxidative stress, leading to expression of antioxidant enzymes, such as catalase, glucose reductase, superoxide dismutase, and heme oxygenase-1, via a SFK-JNK and p38-nuclear factor kappa B signaling pathway. Further, activation of this signaling was also found to regulate release of inflammatory cytokines, including interleukin-6 and interleukin-8, demonstrating the inflammatory potential of LDH-NP.Keywords: layered double hydroxide, mitogen-activated protein kinases, Src family kinases, nuclear factor kappa B, oxidative stress, inflammatory cytokine

Readings from Asia: Questioning America Again

Directory of Open Access Journals (Sweden)

Yerim Kim

2013-06-01

Full Text Available Chang Sei-jin. Sangsangdoen America: 1945 nyǒn 8wol ihu Hangukui neisǒn seosanǔn ǒtteoke mandǔleogǒtnǔnga 상상된 아메리카: 1945년 8월 이후 한국의 네이션 서사는 어떻게 만들어졌는가 [Imagined America: How national narratives of Korea have been constructed since August 1945]. Seoul: Purǔn Yeoksa, 2012.Research on U.S.–South Korean relations has continued steadily over the decades, especially in the fields of history and literature, resulting in many notable studies. However, the general tendency of this scholarship has been to introduce and analyze the United States as a discrete entity. While this perspective is useful in some regards, it is also necessary to investigate how this entity was felt, perceived, and constructed by those on the receiving end. By shifting the focus from “what America was in South Korea” to “how America was imagined in South Korea,” Sei-Jin Chang’s Imagined America: How National Narratives of Korea Have Been Constructed since August 1945 provides an insightful approach to this issue of complexity.

[The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

Science.gov (United States)

Li, Jian; Zhang, Wei; Zhang, Rui-xian

2009-07-01

Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

Study on the effects of Jinqi hypoglycemic table on serum P-sel, TNF-α and HbAlc levels in patients with type two diabetes mellitus

International Nuclear Information System (INIS)

Qi Falian; Xu Jun; Wang Bin; Chen Yingjian; Yin Qiuxia; Ke Bingshen

2007-01-01

Objective: To study the effects of Huang Qi and Huang Lian on serum P-selectin, tumor necrosis factor-α (TNF-α), glucose and glycosylated hemoglobin (HbAlc) levels in patients with type two diabetes mellitus (DM). Methods: Sixty DM2 patients were divided randomly into 2 equal numbered groups: one group were treated with routine hypoglycemic medicine, in other group, Jinqi hypoglycemic tablets were added besides western medicine. Fasting blood glucose, two hour postprandial glucose, HbAlc, P-SLT and TNF-α levels were measured detected before and after three months' treatment. Results: There were no significant differences between the plasma glucose, HbAlc, P-SLT and TNF-α levels (P>0.05) in the JinQi group and western medicine group before treatment. Fasting plasma glucose and postprandial glucose were decreased after treatment in both groups. HbAlc, P-SLT and TNF-α levels were significantly decreased after treatment (P<0.05, P<0.01, P<0.01) in JinQi group. Conclusion: On the basis of treatment with western medicine, additional Huang Lian and Huang Qi could further decrease HbAlc, P-SLT and TNF-α levels, stabilize blood glucose and provide better therapeutic results in patients with type 2 diabetes mellitus. (authors)

Comparison of corneal power obtained from VERION image-guided surgery system and four other devices

Directory of Open Access Journals (Sweden)

Lin HY

2017-07-01

Full Text Available Hung-Yuan Lin,1,* Hsin-Yang Chen,1,2,* Han Bor Fam,3 Ya-Jung Chuang,1 Ronald Yeoh,4 Pi-Jung Lin5 1Universal Eye Center, Zhongli Branch, Zhongli County, TaoYuan City, Taiwan, Republic of China; 2Ophthalmology Department, Ningbo First Hospital, Ningbo, Zhejiang Province, People’s Republic of China; 3Ophthalmology Department, Tan Tock Seng Hospital, Jalan Tan Tock Seng, 4Ophthalmology Department, Eye and Retina Surgeons, Camden Medical Centre, Singapore; 5Universal Eye Center, Xinnan Branch, Taipei City, Taiwan, Republic of China *These authors contributed equally to this work Purpose: To assess the corneal keratometric values obtained using the VERION image-guided surgery system and other devices.Methods: This study evaluated the right eyes of 115 cataract patients before intraocular lens (IOL implantation through consecutive tests using 5 devices: VERION Reference Unit , Placido-based corneal topography (OPD-Scan III, monochromatic light-emitting diodes (LenStar LS900 and AL-Scan, and rotary prism technology (auto kerato-refractometer KR-8800. Analyzed parameters were corneal steep and flat keratometric values (Ks and Kf and corneal astigmatism and axis. These parameters were evaluated using the one-sample two-tailed t-test and the 95% limits of agreement (95% LOAs between the devices.Results: The mean corneal cylinder value measurements were -0.97±0.63 D, -0.88± 0.60 D, -0.90±0.69 D, -0.90±0.67 D, and -0.83±0.60 D with VERION, LenStar, AL-Scan (2.4 mm, OPD III, and KR-8800, respectively. Only KR-8800 showed a significant difference from VERION in the corneal cylinder value (P<0.05. The mean differences in the Kf and Ks of VERION compared to those of OPD III were 0.18±0.45 D and 0.17±0.38 D (P<0.05, respectively. The 95% LOAs of Bland–Altman analysis for the corneal astigmatism axis of the VERION with LenStar, AL-Scan (2.4 mm, OPD III, and KR-8800 were -26.25° to 58.71°, -20.61° to 47.44°, -25.03° to 58.98°, and -27.85�

Optimization and physicochemical characterization of a cationic lipid-phosphatidylcholine mixed emulsion formulated as a highly efficient vehicle that facilitates adenoviral gene transfer

Directory of Open Access Journals (Sweden)

Kim SY

2017-10-01

Full Text Available Soo-Yeon Kim,1,2 Sang-Jin Lee,2 Jin-Ki Kim,3 Han-Gon Choi,3 Soo-Jeong Lim1 1Department of Bioscience and Bioengineering, Sejong University, Seoul, Kwangjin-gu, Seoul, 2Immunotherapeutics Branch, Research Institute, National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, 3College of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Sangnok-gu, Ansan, Republic of Korea Abstract: Cationic lipid-based nanoparticles enhance viral gene transfer by forming electrostatic complexes with adenoviral vectors. We recently demonstrated the superior complexation capabilities of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP emulsion compared with a liposomal counterpart but the cytotoxicity of DOTAP emulsions remained a challenge. The present study is aimed at formulating an emulsion capable of acting as a highly effective viral gene transfer vehicle with reduced cytotoxicity and to physicochemically characterize the structures of virus-emulsion complexes in comparison with virus–liposome complexes when the only difference between emulsions and liposomes was the presence or absence of inner oil core. The emulsion formulation was performed by 1 reducing the content of DOTAP while increasing the content of zwitterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC, and 2 optimizing the oil content. The complexation capability of formulated DOTAP:DMPC mixed emulsions was similar to those of emulsions containing DOTAP alone while displaying significantly lower cytotoxicity. The complexation capabilities of the DOTAP:DMPC mixed emulsion were serum-compatible and were monitored in a variety of cell types, whereas its liposomal counterpart was totally ineffective. Characterization by scanning electron microscopy, transmission electron microscopy, atomic force microscopy, and dynamic light scattering studies indicated that the optimized emulsions spontaneously surrounded the virus particles to generate emulsions that

K nejstarším dějinám rytířů z Lulče

Czech Academy of Sciences Publication Activity Database

Doležel, Jiří

2017-01-01

Roč. 69, č. 1 (2017), s. 12-19 ISSN 0323-2581 Institutional support: RVO:68081758 Keywords : Moravia * relations between the nobility and towns during the Late Middle Ages * lower nobility * Knights of Luleč Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Archaeology

A Tense Situation: Forcing Tumour Progression

Science.gov (United States)

2009-02-01

Bailey AJ. The effects of the Maillard reaction on the physical properties and cell interactions of collagen. Pathol Biol (Paris) 2006;54:387–395... reaction and, following this law, cells in vivo will respond to alterations in the mechanical properties of their surrounding matrix by adjusting...cell marker for testing malignant transformation and metastatic competence. Biophys J 2005;88:3689–369. [PubMed: 15722433] 29. Cross SE, Jin YS, Rao J

JPRS Report, Near East and South Asia, Pakistan

Science.gov (United States)

1992-09-17

thereby ridding the Subcontinent of the cancer that has been eating into its vitals during the last 45 years, was sacrificed at the altar of personal...the Haqiqis. They are Yousaf Khattak, Kamran Choota, Jin Chacha, Man- soor, Kamran, Sarwar, Afzal, Reech, Mama Arshad Khan, Adeeb Ahmed, Shehzad...learn to live. If we want to live a civilised life, this cancer will have to be eliminated. The second serious charge amounts to treason. Here, a

Green procedures for the chemoselective synthesis of acylals and ...

Indian Academy of Sciences (India)

Li C J and Chan T H 1999 Tetrahedron 55 11149. 5. Li C J 2005 Chem. Rev. 105 3095. 6. Greene T W and Wuts P G M 1999 In Protective Groups in Organic Synthesis 3rd ed. (New York: John Wiley and. Sons) p. 306. 7. Gregory M J 1970 J. Chem. Soc. B. 1201. 8. Jin T S, Sun G, Li Y W and Li T S 2002 Green Chem. 4. 255.

The BBN Knowledge Acquisition Project

Science.gov (United States)

1988-09-01

bmawt’s most ban for it w be comdmed a member of toe darn definted by dta concept. A slot consists of ’@A WMa dm@@Wg as W O*Jin do aw sudL 61 a role ne, a...When staking a new concept. KR&IE will prompt for t name of the new concept sod then a pop-up form will app an dt looks shdo Descriti !n Heme you may

Effect of Nickel on the growth of Spirulina maxima (Arthrospira)

Energy Technology Data Exchange (ETDEWEB)

Dominguez-Bocanegra, A. R.; Torres-Munoz, J. A.; Neria-Gonzalez, M. I.; Rios-Leal, E.; Aguilar-Lopez, R.

2009-07-01

Nickel is not produced in Mexico, but is a component widely used in the paper industry, fertilizers, iron foundry, and jewels fabrication among others. therefore it is founded in residual waters coming form domestic and industrial. It is known that such a heavy metal is essential to the life of some microorganisms including microalgae, however at relatively high concentrations it turns to be toxic inside some physiological processes (Jin et al., 1996). (Author)

China Report, Political, Sociological and Military Affairs, No. 445.

Science.gov (United States)

1983-08-11

2052 0981], Chen Dingming [7115 7844 6900], Jin Xiulan [6855 4423 5695] (F, Mongolian), Zhao Nanqi [6392 0589 6386] Korean), Suo Jingxian [4792...Pen Center and the Guangzhou Pen Center will be headed by Chen Huangmei, another vice-president of the China center and a noted critic. The...1728 4426 6311], Zhang Tengxiao [1728 7506 7197], Chen Dingmou [7115 0002 5399], Chen Lunfen [7115 0243 5358] (F), Chen Xitong [7115 1585 0681

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 7. Fairlane Gear, Incorporated-General Fiberglass Fabricators.

Science.gov (United States)

1987-01-01

n " L(140(00 0 ( -00 (D -0 -i- F- C") (.1 I-- (0(0LJ I jInI x I.( < .41 000000000 0000 -100000 -10000 woo0 (0 00 000 0L j0 0000 I( < 4 InO 0000000...44 0 NO "(00-40-4_-4 MD -t ONj I4 NI" 000 ZO 0CD00) 00 (0 woo w0-4000000 F-0 GAO 0-14 (𔃾 00 0 0Cm) z1- 4 < Cm) I -in inin -0 01-(0 (00 01 rC- Cm) IC...I I at % - * 0- 1 02-lZ I Lw c4 r 4 4 jIN CJI-4 JINNNinN -tr(jJNM JINI #NI NINN -JIACINjNN NC\\N--INNN NN-4NN INIJ--N(, >WI -,I - - - - - nC lI MIIr)" l

Non-radiative Exciton Decay in Single-walled Carbon Nanotubes

Science.gov (United States)

Harrah, Mark; Swan, Anna

2010-03-01

Experiments have shown step-wise changes in the fluorescence intensity from single-walled carbon nanotubes [1,2]. It has been proposed that the underlying mechanism for the step-wise changes is diffusion-limited quenching of excitons at defects [1]. This property has been used to demonstrate single-molecule detection for biological applications [3]. We perform a Monte-Carlo simulation of nanotube fluorescence with a diffusion-limited quenching model. The fluorescence intensity is seen to depend on the mean-square distance between defects, implying a nonlinear dependence on the number of defects. The intensity for consecutive defect counts can overlap depending on the positions of the defects. [4pt] [1] Cognet, L. et al. Science 316, 1465-1468 (2007).[0pt] [2] Jin, H. et al. Nano Lett. 8, 4299-4304 (2008).[0pt] [3] Heller, D. A. et al. Nature Nanotech. 4, 114-120 (2009).

Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/D-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment

Directory of Open Access Journals (Sweden)

Wu H

2016-11-01

Full Text Available Hao Wu,1–3 Qingxiang Zhong,1,2 Rongling Zhong,4 Houcai Huang,4 Zhi Xia,4 Zhongcheng Ke,1,5 Zhenhai Zhang,1 Jie Song,1,2 Xiaobin Jia1–3 1Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, 2Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Province Academy of Chinese Medicine, Nanjing, Jiangsu, 3College of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, 4Laboratory Animal Center, Jiangsu Province Academy of Chinese Medicine, Nanjing, Jiangsu, 5College of Chemistry and Chemical Engineering, Huangshan University, Huangshan, Anhui, People’s Republic of China Abstract: Oleanolic acid (OA is a triterpenoid found in various fruits and vegetables and used in traditional Chinese medicine. OA plays a crucial role in the treatment of several cancers, but poor water solubility, low permeability, and significant efflux have limited its widespread clinical use. Vitamin E-D-α-tocopheryl polyethylene glycol succinate (vitamin E-TPGS and Pluronic P105 were used to improve the solubility and permeability and to decrease the efflux of OA. OA-loaded mixed micelles were prepared by ethanol thin-film hydration. The physicochemical properties of the micelles, including zeta potential, morphology, particle size, solubility, drug loading, and drug entrapment efficiency were characterized. OA release from micelles was slower than that from the free drug system. OA uptake by A549 non-small-cell lung cancer (NSCLC cells was enhanced by the micelles. A tumor model was established by injecting A549 cells into nude mice. In vivo imaging showed that OA-micelles could accumulate in the tumors of nude mice. Additionally, smaller tumor size and increased expression of pro-apoptotic proteins were observed in OA-micelle-treated mice, indicating that OA-micelles are more effective than free OA in treating cancer. In vitro experiments were performed using two NSCLC cell

Color in packaging design : Case: ZheJiang JinSheng packaging Co,Ltd

OpenAIRE

Hu, Cuicui

2010-01-01

Color occupies an important position in packaging design, with the improvement of living standard, the higher requirement of color design in packaging. The aim of this thesis was to discuss key issues concerning aesthetics of packaging design. Topics will include an overview of the packaging design, the influence factor of packaging design, and introduce the aesthetics from packaging aspect. This thesis will also identify common problems of the production process, and list the phases of ho...

Artificial control of biocatalytic reaction; Seitai shokubai hanno no jin`iteki seigyo

Energy Technology Data Exchange (ETDEWEB)

Nakamura, K. [Kyoto University, Kyoto (Japan). Institute for Chemical Research

1997-08-25

Selective composition of optically active compounds by use of biocatalysts is discussed. No search is made for any particular microbes or enzymes, but predetermined ones are used. For an increase in the selective yield of L-type carnitine by reducing 4-chloroacetoacetic acid ester using baker`s yeast, the ester length should be enlarged to that of octyl ester. Just as in this case, steric control by ground substance modification is often effective. Lipase helps on esterification which is contrary to hydrolysis in an organic solvent and, even in the optical division in this process, steric control by ground substance modification (for example by changing the structure of the acyl section) is effective. Immobilization of biocatalysts for use in reaction occasionally exerts some effect on stereoselectivity. Two types of enzymes may be participating in a reaction and inhibiting selectivity, and then a two-layer system of water and organic solvent may be effective in performing steric control over the situation. Another measure is to inhibit the activity of either of the two enzymes by use of a selective inhibitor utilizing enzyme reaction. The kind of solvent is also an influential factor. 11 refs., 7 figs.

Dějin Ruska se již bát nemusíme

Czech Academy of Sciences Publication Activity Database

Nykl, Hanuš

2017-01-01

Roč. 30, 26.08.2017 (2017), IX/25 ISSN 0862-5921 Institutional support: RVO:68378017 Keywords : historiography * Russia * history Subject RIV: AB - History OBOR OECD: Philosophy, History and Philosophy of science and technology

Eleven lectures on the physics of the quark-gluon plasma

International Nuclear Information System (INIS)

McLerran, L.

1984-10-01

These lectures are intended to be an introduction to the physics of the quark-gluon plasma, and were presented at a workshop on The Physics of the Quark-Gluon Plasma held at Hua-Zhong Normal University in Wuhan, People's Republic of China in September, 1983. The lectures cover perturbation theory of the plasma at high temperature as well as the non-perturbative methods and results of lattice gauge theory computations. Physical models of the confinement-deconfinement phase transition and the modes of chiral symmetry breaking are presented. The possibility that a quark-gluon plasma might be produced in ultra-relativistic nuclear collisions is analyzed. Separate entries were prepared for the data base for the eleven lectures

Enhanced methanol oxidation and oxygen reduction reactions on palladium-decorated FeCo@Fe/C core–shell nanocatalysts in alkaline medium

CSIR Research Space (South Africa)

Fashedemi, OO

2013-12-01

Full Text Available . Zhong, J. Luo, B. Fang, B. N. Wanjala, P. N. Njoki, R. Loukrakpam and J. Yin, Nanotechnology, 2010, 21, 062001. 39 C. L. Lee, H. P. Chiou, C. M. Syu, C. R. Liu, C. C. Yang and C. C. Syu, Int. J. Hydrogen Energy, 2011, 36, 12706–12714. 40 K. J. Mayrhofer..., 12, 1102–1106. 2 Y. W. Lee, M. Kim, Y. Kim, S. W. Kang, J. H. Lee and S. W. Han, J. Phys. Chem. C, 2010, 114, 7689–7693. 3 C. Zhu, S. Guo and S. Dong, J. Mater. Chem., 2012, 22, 14851–14855. 4 C. Jeyabharathi, P. Venkateshkhumar, J. Mathiyarasau and K...

A Model of Dynamic Strategy-Making

DEFF Research Database (Denmark)

Andersen, Torben Juul; Hallin, Carina Antonia; Li, Xin

The organizational capacity to cope with unexpected changes remains a fundamental challenge in strategy as global competition and technological innovation increase environmental uncertainty. Conventional strategy-making is often conceived as a sequential linear process where we see it as a non......-linear interaction between top-down and bottom-up mechanisms dealing with multiple actions taken throughout the organization over time. It is driven by intension but with a flexible balance between centralized (planned) and decentralized (spontaneous) activities. We adopt the principles of complementary Yin......-Yang elements and Zhong Yong balance to explain the time bound interaction between these opposing yet complementary strategy-making mechanisms where tradeoffs and synergies are balanced across hierarchical levels....

Evaluation of the antioxidant and endothelial protective effects of Lysimachia christinae Hance (Jin Qian Cao) extract fractions.

Science.gov (United States)

Wu, Ning-Hua; Ke, Zhi-Qiang; Wu, Shan; Yang, Xiao-Song; Chen, Qing-Jie; Huang, Sheng-Tang; Liu, Chao

2018-04-10

Lysimachia christinae Hance is a traditional Chinese medicine with diuretic, detumescent, and detoxifying effects. Our aimed to optimize the extraction protocol to maximize the yield of flavonoids from Lysimachia christinae Hance, and evaluate the pharmacological activities of four fractions, namely, petroleum ether (PE), ethyl acetate (EA), n-butanol (NB), and aqueous (AQ) fractions, of the ethanolic extract of Lysimachia christinae Hance. The flavonoid monomers in the crude extract were characterized via high performance liquid chromatography (HPLC), were used as markers for extract quality control and standardization. The total flavonoid, total phenolic, and total polysaccharide contents of each fraction were determined by spectrophotometry. Further, the in vitro free radical (diphenylpicrylhydrazyl, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid), superoxide, and hydroxyl radicals) scavenging activities, and antioxidant capacity in endothelial cells were evaluated for each fraction. After optimizing the extraction protocol to maximize the total flavonoid yield from L. christinae Hance, the NB fractions had the highest total flavonoid (39.4 ± 4.55 mg RE/g), total phenolic (41.1 ± 3.07 mg GAE/g) and total polysaccharide (168.1 ± 7.07 mg GE/g); In addition, the NB fraction of the ethanolic extract of L. christinae Hance reveal the strongest radical-scavenging activity, antioxidant activity and protective effects against H 2 O 2 -induced injury in HUVECs. Among the four fractions of L. christinae Hance, the NB fraction showed the most potent antioxidant and endothelial protective effects, which may be attributed to its high flavonoid, phenolic contents and optimal portfolio of different active ingredients of NB fractions of the ethanolic extract of L. christinae Hance. This study might improve our understanding of the pharmacological activities of L. christinae Hance, thereby facilitating its use in disease prevention and treatment.

The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages

Directory of Open Access Journals (Sweden)

Li XS

2015-01-01

Full Text Available Xuesong Li,1,* Lei Gao,2,* Longbin Zheng,1 Jiayuan Kou,1 Xing Zhu,1 Yueqing Jiang,1 Zhaoyu Zhong,1 Juhua Dan,1 Haobo Xu,3 Yang Yang,3 Hong Li,1 Sa Shi,1 Wenwu Cao,4,5 Yajun Zhao,1 Ye Tian,1,3 Liming Yang1 1Department of Pathophysiology, Harbin Medical University, Harbin, People’s Republic of China; 2Electron Microscopy Centre, Harbin Medical University, Harbin, People’s Republic of China; 3Division of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, People’s Republic of China; 4Laboratory of Sono- and Photo-theranostic Technologies, Harbin Institute of Technology, Harbin, People’s Republic of China; 5Materials Research Institute, The Pennsylvania State University, University Park, PA, USA *These authors contributed equally to this work Purpose: To investigate the sonoactivity of hypericin (HY, together with its sonodynamic effect on THP-1 macrophages and the underlying mechanism.Materials and methods: CCK-8 was used to examine cell viability. Confocal laser scanning microscopy was performed to assess the localization of HY in cells, reactive oxygen species (ROS generation, and opening of the mitochondrial permeability transition pore (mPTP after different treatments. Apoptosis was analyzed using Hoechst–propidium iodide and transmission electron microscopy. Mitochondrial membrane potential (ΔΨm collapse was detected via fluorescence microscopy. Lipoprotein oxidation was determined in malondialdehyde (MDA assays. Western blotting was conducted to determine the translocation of BAX and cytochrome C and the expression of apoptosis-related proteins.Results: HY was sublocalized among the nuclei and the mitochondria, endoplasmic reticulum, Golgi apparatus, and lysosome in the cytosol of THP-1 macrophages. Under low-intensity ultrasound irradiation, HY significantly decreased cell viability and induced apoptosis. Furthermore, greater ROS generation, higher MDA levels, and greater ΔΨm loss were observed in the

Multiscale Mathematics for Nano-Particle-Endowed Active Membranes and Films

Science.gov (United States)

2016-08-03

graduated and move on to either continue their postdoc training or working in universities and industries . The team has been very productive during...6402. 21. Hua Jiang, Hao Yang, Jun Zeng, Zhiyuan Zhou, Jin Peng, Qi Wang, Analytic Oncology, Electron J Metab Nutr Cancer，Jun. 2015，Vol. 2， No. 2, 26...approved for public release. 6 Hill, July 2016-present 2. Norazaliza Mond Gamil, PhD May 2015, Universiti Malaysia Pahang, 2015- present 3. Chen

China Report Economic Affairs No. 348.

Science.gov (United States)

1983-06-08

Tax-for-Profit System in Beijing ( JINGJI GUANLI, 5 Mar 83) 36 FINANCE AND BANKING Control of Extra-Budgetary Funds Stressed (Jin Xin; CAIZHENG...representatives of the intellectuals and fine scientific workers; from Zhu Boru, the living Lei Feng; and from Zhang Haidi, fine CYL member and...SYSTEM IN BEIJING HK201033 Beijing JINGJI GUANLI in Chinese No 3, 5 Mar 83 pp 28-30 [Article by the Financial and Banking Group of the State Council

CXCL14 Blockade of CXCL12/CXCR4 Signaling in Prostate Cancer Bone Metastasis

Science.gov (United States)

2017-10-01

10.1158/0008-5472.CAN-04-3785. 55. Jung Y, Kim JK, Shiozawa Y, Wang J, Mishra A, Joseph J, Berry JE, McGee S, Lee E, Sun H, Wang J, Jin T, Zhang H...and unfortunate complication of advanced prostate cancer resulting in significant pain and fractures . The most devastating consequence, however, is...treatments. These data suggest a mechanism of increased migration and invasion may be associated with expression of EMT genes. Regulation of Kinase

"Glimpses of the Duanwu Festival" by Fang Xun (1736-1799) : commemorative painting or private souvenir ?

OpenAIRE

Kerlan-Stephens , Anne

2001-01-01

International audience; Fang Xun (1736 or 1737-1799) was a painter from the Hangzhou area who is now known essentially as the author of a treatise on painting, although he enjoyed during his lifetime local artistic fame. This paper details his relationship with a network of friends and clients belonging to the local gentry through the analysis of a painting he realized around 1780, describing a gathering at the estate of his main patron, Jin Deyu (1750-1800).

Materials Science and Engineering-1989 Publications (Naval Research Laboratory)

Science.gov (United States)

1991-03-29

Antamanide J.H. Konnert, P. D’Antonio, J.M. Cowley, and Analog. Crystal Structure of A. Higgs , H-J. Ou Perhydrosymmetric antamanide, Ultramicroscopy, 30, 371...Paired Boson Superconductor" Molecular Beam Epitaxy" W. Jin, S.D. Mahanti, A.K. Rajagopal A. Christou, N. Flevaris, A. Georgakilas, Solid State...33(3), 347-358 Si(100)" "Neutron Scattering from Fermion and S.M. Prokes, W.F. Tseng, A- Christou Boson Superconductors" Materials Research Society

Bibliography of NRL Publications - 1989

Science.gov (United States)

1993-05-01

Physical Review B Paired Boson Superconductors, by Jin, W.*, 38:12807-12813, 1988. Mahanti, S.D.*, and Rajagopal, A.K., Solid State Communications 71...967-971, 1989. Molecular Beam Epitaxy Growth of InSb Films on GaAs, by Davis, J.L. and Thompson, Neutron Scattering from Fermion and Boson P.E...Nanodiffraction Patterns from Physical Review B 40:6374-6380, 1989. Overlapping Regions: Si[110], by Konnert, J.H., D’Antonio, P., Cowley, J.M.*, Higgs , A

Modulation of Estrogen-Depurinating DNA Adducts by Sulforaphane for Breast Cancer

Science.gov (United States)

2014-12-01

system in cancers: stress response and anabolic metabolism. Front. Oncol., 2, 200. doi: 10.3389/ fonc.2012.00200. 20. Agyeman,S.A. et  al. (2012...to science education and young scientists. We look forward to working with you. Sincerely, Chuck  37 From: "Gary A. Lorigan...Drosophila," by Ki Moon Seong, Mira Yu, Kyu-Sun Lee, Young Woo Jin and Kyung J. Min, and for taking the time and effort to review this manuscript. Best

Position-specific isotope modeling of organic micropollutants transformations through different reaction pathways

Science.gov (United States)

Jin, Biao; Rolle, Massimo

2016-04-01

Organic compounds are produced in vast quantities for industrial and agricultural use, as well as for human and animal healthcare [1]. These chemicals and their metabolites are frequently detected at trace levels in fresh water environments where they undergo degradation via different reaction pathways. Compound specific stable isotope analysis (CSIA) is a valuable tool to identify such degradation pathways in different environmental systems. Recent advances in analytical techniques have promoted the fast development and implementation of multi-element CSIA. However, quantitative frameworks to evaluate multi-element stable isotope data and incorporating mechanistic information on the degradation processes [2,3] are still lacking. In this study we propose a mechanism-based modeling approach to simultaneously evaluate concentration as well as bulk and position-specific multi-element isotope evolution during the transformation of organic micropollutants. The model explicitly simulates position-specific isotopologues for those atoms that experience isotope effects and, thereby, provides a mechanistic description of isotope fractionation occurring at different molecular positions. We validate the proposed approach with the concentration and multi-element isotope data of three selected organic micropollutants: dichlorobenzamide (BAM), isoproturon (IPU) and diclofenac (DCF). The model precisely captures the dual element isotope trends characteristic of different reaction pathways and their range of variation consistent with observed multi-element (C, N) bulk isotope fractionation. The proposed approach can also be used as a tool to explore transformation pathways in scenarios for which position-specific isotope data are not yet available. [1] Schwarzenbach, R.P., Egli, T., Hofstetter, T.B., von Gunten, U., Wehrli, B., 2010. Global Water Pollution and Human Health. Annu. Rev. Environ. Resour. doi:10.1146/annurev-environ-100809-125342. [2] Jin, B., Haderlein, S.B., Rolle, M

Development and blood compatibility assessment of electrospun polyvinyl alcohol blended with metallocene polyethylene and plectranthus amboinicus (PVA/mPE/PA for bone tissue engineering

Directory of Open Access Journals (Sweden)

Qi J

2018-05-01

Full Text Available Jie Qi,1,* Huang Zhang,2,* Yingzhou Wang,3 Mohan Prasath Mani,4 Saravana Kumar Jaganathan5–7 1Department of Orthopedics, Shaanxi Provincial People’s Hospital, 2Department of Orthopedics, Han Zhong People’s Hospital, Han Zhong, Shaanxi Province, 3Beijing Meinuoyikang Health Food Co., Ltd, Beijing, People’s Republic of China; 4Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia; 5Department for Management of Science and Technology Development, 6Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam; 7IJN-UTM Cardiovascular Engineering Centre, Department of Clinical Sciences, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia *These authors contributed equally to this work Introduction: Currently, the design of extracellular matrix (ECM with nanoscale properties in bone tissue engineering is challenging. For bone tissue engineering, the ECM must have certain properties such as being nontoxic, highly porous, and should not cause foreign body reactions. Materials and methods: In this study, the hybrid scaffold based on polyvinyl alcohol (PVA blended with metallocene polyethylene (mPE and plectranthus amboinicus (PA was fabricated for bone tissue engineering via electrospinning. The fabricated hybrid nanocomposites were characterized by scanning electron microscopy (SEM, Fourier transform and infrared spectroscopy (FTIR, thermogravimetric analysis (TGA, contact angle measurement, and atomic force microscopy (AFM. Furthermore, activated partial thromboplastin time (APTT, prothrombin time (PT, and hemolytic assays were used to investigate the blood compatibility of the prepared hybrid nanocomposites. Results: The prepared hybrid nanocomposites showed reduced fiber diameter (238±45 nm and also increased porosity (87% with decreased pore diameter (340±86 nm compared with pure PVA. The interactions between PVA, m

Major geological events and uranium metallogenesis in South-west China

International Nuclear Information System (INIS)

Zhang Chengjiang; Xu Zhengqi; Ni Shijun; Chen Youliang

2012-01-01

Uranium is widely distributed in South-west China, with all types but on a not-so-large scale. South-west China is located on the combining site of several large tectonic elements and every tectonic movement has different effects on different regions. To study and clarify the correlation between the major geological events in South-west China and the Uranium metallogenesis, comprehensive research and field investigation are made besides collecting a lot of materials. Through analysis and research on the major geological events in South-west China, the evolution of those e vents is basically clarified and the events closely related with uranium mineralization are determined. It is discovered that there are several ore-forming geologic events in the geological history of South-west China; almost every major tectonic movement cycle is accompanied with uranium metallogenesis, from Jinning Movement to Chengjiang Movement, to Hercynian Movement, to Indosinian Movement. to Yanshan Movement. to Himalayan movement. Even though every major tectonic cycle is accompanied with uranium mineralization, three major geological events are generally obviously related with uranium metallogenesis, i.e. the Rodinian supercontinent breakup even in Jinning-Chengjiang Period, Yanshan Movement and Himalayan movement, in which the first one is the process of uranium pre-enrichment and provides the source of uranium. Yanshan Movement and Himalayan movement are the important processes for mineralization, mainly the hydrothermal superimposed mineralization. (authors)

Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid

Science.gov (United States)

Taha, Ameer Y.; Chang, Lisa; Chen, Mei

2016-01-01

Background This study tested the dietary level of alpha-linolenic acid (α-LNA, 18:3n-3) sufficient to maintain brain 14C-Docosahexaenoic acid (DHA, 22:6n-3) metabolism and concentration following graded α-LNA reduction. Methods 18–21 day male Fischer-344 (CDF) rats were randomized to the AIN-93G diet containing as a % of total fatty acids, 4.6% (“n-3 adequate”), 3.6%, 2.7%, 0.9% or 0.2% (“n-3 deficient”) α-LNA for 15 weeks. Rats were intravenously infused with 14C-DHA to steady state for 5 minutes, serial blood samples collected to obtain plasma and brains excised following microwave fixation. Labeled and unlabeled DHA concentrations were measured in plasma and brain to calculate the incorporation coefficient, k*, and incorporation rate, Jin. Results Compared to 4.6% α-LNA controls, k* was significantly increased in ethanolamine glycerophospholipids in the 0.2% α-LNA group. Circulating unesterified DHA and brain incorporation rates (Jin) were significantly reduced at 0.2% α-LNA. Brain total lipid and phospholipid DHA concentrations were reduced at or below 0.9% α-LNA. Conclusion Threshold changes for brain DHA metabolism and concentration were maintained at or below 0.9% dietary α-LNA, suggesting the presence of homeostatic mechanisms to maintain brain DHA metabolism when dietary α-LNA intake is low. PMID:26869088

Provenance study of ancient Chinese Yaozhou porcelain by neutron activation analysis

Science.gov (United States)

Li, G. X.; Y Gao, Z.; Li, R. W.; Zhao, W. J.; Xie, J. Z.; Feng, S. L.; Zhuo, Z. X.; Y Fan, D.; Zhang, Y.; Cai, Z. F.; Liu, H.

2003-09-01

This paper reports our study of the provenance of ancient Chinese Yaozhou porcelain. The content of 29 elements in the Yaozhou porcelain samples was measured by neutron activation analysis (NAA). The NAA data were further analysed using fuzzy cluster analysis to obtain the trend fuzzy cluster diagrams. These samples with different glaze colour, ranging over more than 700 years, were fired in different kilns. Our analysis indicates the relatively concentrated distribution of the sources of the raw material for the Yaozhou porcelain body samples. They can be classified into two independent periods, i.e. the Tang (AD 618-907) and the Five Dynasties (AD 907-960) period, and the Song (AD 960-1279) and Jin (AD 1115-1234) period. Our analysis also indicates that the sources of the raw material for the ancient Yaozhou porcelain glaze samples are quite scattered and those for the black glaze in the Tang Dynasty are very concentrated. The sources of the raw material for the celadon glaze and the white glaze in the Tang Dynasty are widely distributed and those for the celadon glaze in the Song Dynasty are close to those of the bluish white glaze in the Jin Dynasty, and they are very concentrated. The sources of the raw material for the porcelain glazes cover those of the porcelain bodies.

'Made in Europe' photovoltaic industry Conference - perspectives in the face of the crisis?'

International Nuclear Information System (INIS)

Masson, Gaetan; Goeke, Berthold; Barber, Nicolas; Frey, Peter; Laborde, Eric; Michael Lippert; Matthias Reichmuth; Daniel Lincot

2011-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the future of the photovoltaic industry. In the framework of this French-German exchange of experience, about 120 participants exchanged views on some innovative projects, as well as some solutions to grid integration and electricity storage. The question of anticipated grid parity through self-consumption was addressed too. This document brings together the available presentations (slides) made during this event: 1 - PV, a competitive source of energy in Europe: tomorrows' grid parity and markets in Europe (Gaetan Masson); 2 - Photovoltaics support in Germany - developments and challenges (Berthold Goeke); 3 - New support mechanism to the photovoltaic industry: optimizing the model, the French market asset (Nicolas Barber); 4 - PV production in Germany - threats and opportunities (Peter Frey); 5 - PV Alliance - From Labs to Fabs: ensuring the photovoltaic industry future through innovation and R and D collaborations in France and Germany (Eric Laborde); 6 - Smart energy storage improving grid integration of decentralized PV energy (Michael Lippert); 7 - Onsite Consumption - the anticipated Grid Parity (Matthias Reichmuth); 8 - The photovoltaic energy research and development institute - IRDeP (Daniel Lincot)

Arbitration in environmental matters. An interdisciplinary introduction; Studienbrief Umweltmediation. Eine interdisziplinaere Einfuehrung

Energy Technology Data Exchange (ETDEWEB)

Claus, F; Fietkau, H J; Fuchs, G [and others

2000-07-01

This textbook provides a comprehensive and systematic introduction to the process of arbitration in environmental matters, both for self-studies and for participants in the seminars on which it is based. The interdisciplinary readership is reflected in the interdisciplinary group of authors. The publication can be used as a training programme. [German] Mit Vorliegen dieses Studienbriefs wird erstmals eine Moeglichkeit geboten, sich umfassend und systematisch, im Eigenstudium oder im Rahmen des dazugehoerigen Seminarprogramms, mit dem Verfahren der Umweltmediation vertraut zu machen. Der Vielfalt der angesprochenen Zielgruppen (Politik, Verwaltung, Wirtschaft, Rechtswesen usw.) wurde in der interdisziplinaeren Zusammensetzung des Autorenkreises Rechnung getragen. Das Layout wurde so gestaltet, dass es die inhaltliche Orientierung erleichert. Zusaetzlich kann der Studienbrief auch als Bauelement fuer eine umfassendere Wissensaneignung dienen: Erstens ist es moeglich, sich ueber das oben genannte Ausbildungsprogramm fuer Praktiker zum Mediator fortzubilden. Zweitens besteht die Chance, das erworbene Wissen durch einen Lehrgang zur Agenda-Moderation des Wissenschaftsladen Bonn e.V. um weitere konsens- und handlungsorientierte Verfahren zu erweitern. Informationen koennen ueber den Foerderverein Umweltmediation e.V., Matthias-Gruenewald-Str. 1-3, 53175 Bonn, Tel. 0228/3 72 99 27, eingeholt werden. (orig.)

Local Governance and Corruption

Directory of Open Access Journals (Sweden)

Marius PROFIROIU

2006-06-01

Full Text Available This paper attempts to examine, from the Romanian perspective, the degree to which decentralization process and improvement of local governance contributes to the reduction of corruption in the short and medium term. Through the methodology that is used the paper is consistent with the international trend that endeavors to analyze the impact of corruption on economic and social processes at the local level. In addition, recent research on corruption issues has focused upon the measurement of the level of corruption level and on its impact on the growing rate of the GDP (Mauro [1995]1, Abed and Davoodi2, Krueger [1974]3, on the impact upon some of the national economical sectors (Tanzi [1998]4, Shang-Jin Wei [2001]5, or on the decentralization processes (Shah [2006]6.

Comparative DEMS study on the electrochemical oxidation of carbon blacks

DEFF Research Database (Denmark)

Ashton, Sean James; Arenz, Matthias

2012-01-01

Publication year: 2012 Source:Journal of Power Sources, Volume 217 Sean J. Ashton, Matthias Arenz The intention of the study presented here is to compare the electrochemical oxidation tendencies of a pristine Ketjen Black EC300 high surface area (HSA) carbon black, and four graphitised counterparts...... heat-treated between 2100 and 3200 °C, such as those typically used as corrosion resistant carbon (CRC) supports for polymer electrolyte membrane fuel cell (PEMFC) catalysts. A methodology combining cyclic voltammetry (CV) and differential electrochemical mass spectrometry (DEMS) is used, which allows......; however, CRC samples graphitised =2800 °C did not exhibit this same behaviour. Highlights ¿ We quantitatively determine electrooxidation of carbon support materials. ¿ We can distinguish between the total and partial electrooxidation. ¿ Non or mildly heat treated carbon forms passivating layer. ¿ Heat...

DEGRADATION WORKS OF MONUMENTAL ART CAST BRONZE UNDER THE INFLUENCE OF ENVIRONMENTAL FACTORS

Directory of Open Access Journals (Sweden)

Delia NICA-BADEA

2012-11-01

Full Text Available Intensive pollution, combined with the lack of conservation of monuments exposed to these environments make the main cause of deterioration of cultural objects to atmospheric corrosion metal. This paper proposes a study of the main factors leading to degradation Bronze alloy, cast bronze monuments exposed to open atmosphere: corrosive environmental factors, stability and products of corrosion of bronze. In general, all corrosion products present on a metal surface are indicated as 'skate', can be composed of single-layer or multilayer products. The paper also includes a case study on the influence of environmental factors on degradation Matthias monument statue in Cluj-Napoca, Romania. Visual inspection of the monument informs us that have white spots, gray, reddish not consistent with the base color green patina, surfaces showing depigmentation, the rain washed areas, crystallization, deposition of air-borne particles.

Huysmans e Gonzaga Duque: transposições de arte em textos franceses e brasileiros do Simbolismo

Directory of Open Access Journals (Sweden)

André Soares Vieira

2013-12-01

Full Text Available Este ensaio pretende refletir sobre alguns processos de tradução de obras picturais transpostas para textos críticos e literários. O processo de transposição escrita da pintura será examinado segundo uma análise do discurso sobre arte produzido pelo escritor e crítico brasileiro Gonzaga Duque (1863-1911 e pelo romancista e também crítico de arte francês Joris-Karl Huysmans (1848- 1907. O objetivo é o de mapear, através de obras dos pintores Matthias Grünewald (1470-1528 e Félicien Rops (1833-1898, alguns modos de transferência entre a arte pictórica e os textos críticos e literários, tomando-se por base, sobretudo, os estudos de Françoise Lucbert.

Famous Food in Beijing

Institute of Scientific and Technical Information of China (English)

1997-01-01

MORE than 3,000 years have passed since Shao Gongshi was granted territory at Yon (Beijing) by the King of Zhon in 1045 B.C. Ever since,Beijing has had a long and glorious history as the capital for five Chinese feudal dynasties--the Liao (907-1125), Jin (1115-1234),Yuan (1206-1368), Ming (1368-1644) and Qing(1644-1911). As a political, cultural and economic centre,Beijing has formed a unique taste on food with many long-lasting, wellknown eateries.

Alcohol-Induced Physiological Displacements and Their Effects on Flight-Related Functions

Science.gov (United States)

1982-03-01

measured height and weight (6). One part bourbon per two parts of Coca Cola were mixed, divided equally into three drinks and drunk at an even rate over a...temporary protection against a plasma volume decrease (21). In our study, the imbibed volume of alcohol plus Coca Cola (about 350-550 ml) temporarily...amE E T Office of Aviation Medicine MAY 2 7 1982 Washington, D.C. 20591A~A C.-, t(Jin NOTICE This document is disseminated under the sponsorship of

Armed Forces Institute of Regenerative Medicine Annual Report 2011

Science.gov (United States)

2012-01-01

using the virus . They have generated high titer viruses for both the decorin and CAR- decorin and produced high yields of decorins devoid of the...involve goats, sheep, dogs, cats , and primates with nerve gaps ranging from 3–90 mm. However, large animal studies are very expensive and take 2–4 years...Leader(s): George Christ, PhD (WFIRM) Project Team Members: James Yoo, MD, PhD, Sang Jin Lee, PhD, Benjamin T. Corona , PhD, and Masood A

Uji Toksisitas Ekstrak Tinta Cumi-Cumi (Photololigo Duvaucelii) Dengan Metode Brine Shrimp Lethality Test (Bslt)

OpenAIRE

Kurniansyah, Wendra

2015-01-01

During this people considers that squid ink is not useful so that if processing squid, the ink was removed. Based on research conducted by Sasaki and colleagues Jin'ichi of Hirosaki University in northern Japan, squid ink can activates white blood cells to fight cancer. The compound is thought to have anti-cancer activity should be tested first in animals before being developed further. The purpose of this study are determining and comparing the toxicity of the components of biological akti...

A new find of the fossil Cyclosorus from the Eocene of South China and its paleoclimatic implication.

Science.gov (United States)

Naugolnykh, Serge V; Wang, Li; Han, Meng; Jin, Jian-Hua

2016-01-01

The thelypteroid ferns are widely distributed across tropical regions around the world, but information about their fossil representatives is scarce. A new species, Cyclosorus scutum Naugolnykh, Wang, Han et Jin was discovered from the Eocene Changchang Formation of Hainan Island, South China, and is described on the basis of sterile and fertile leaves, sori, sporangia and spores preserved in situ. Discovery of this new species clearly shows that climatic conditions of that time in this area were humid, i.e. warm and wet.

An Integrative Model of Dynamic Strategy-Making

DEFF Research Database (Denmark)

Andersen, Torben Juul; Hallin, Carina Antonia; Li, Xin

. We adopt the frame of complementary Yin-Yang elements and Zhong Yong balance to explain the time bound interaction between these opposing yet complementary strategy-making mechanisms where tradeoffs and synergies are balanced across hierarchical levels. The model outlines how the interaction between......The organizational capacity to cope with unexpected changes remains a fundamental challenge in strategy as global competition and technological innovation increase environmental uncertainty. Whereas conventional strategy-making often is conceived as a sequential linear process, we see it as a non......-linear interaction between top-down and bottom-up mechanisms dealing with multiple actions taken throughout the organization over time. It is driven by intension but with a flexible balance between centralized (planned) and decentralized (spontaneous) activities where strategy formulation and implementation interact...

From“Expression of Feelings” to“Landscape”：Independence of Image of landscape in Travelling Poems in Wei and Jin Dynasties%从“咏怀”到“山水”：魏晋羁旅行役诗中山水物色的独立之路

Institute of Scientific and Technical Information of China (English)

程磊

2015-01-01

羁旅诗长期遵循着言志抒情的咏怀思路，自然物象无法凸显独立出来，随着魏晋时代山水审美意识的勃兴以及山水游览风气的盛行，行旅诗也逐渐增加山水描写的比重，并将山水游赏与羁旅情思结合起来，二者融合才有谢灵运羁旅山水诗的出现。其间玄言山水诗以山水阐说玄理，注重祛情去累、以理遣情，将羁旅的困境体验导向证悟哲理玄境的解脱，山水显得外在而与诗人的精神世界难以相契，至南朝尤其是谢朓的宦游山水诗篇，山水形象与世俗生活情感相交融，才有羁旅山水诗歌传统的正式定型。从羁旅咏怀到羁旅山水，情事相生转变为情景相照，正是山水诗诞生的内在理路之一。%For a long time poems about intellectuals'business trip had followed the lyric pattern so the image of landscape could not be protruded .Due to the rise of landscape aesthetics and the fashion of landscape sightseeing in Wei and Jin Dynasties ,the proportion of landscape description in business trip poems had in‐creased ,as well as the combination with sightseeing and nostalgia ,which brought about Xie Lingyun's land‐scape poems .Before that ,landscape in metaphysical poems explained the metaphysics through landscape , emphasizing weakening of feelings and guiding predicament experience of intellectuals'business trip to un‐derstanding of philosophy .The external landscape could not agree with the poet's spirit .Not until the South Dynasty did the landscape and the worldly life integrated with each other and the tradition of landscape po‐ems about business trip is established .Landscape as a way of life emerges slowly during the poem‐evolving course .It is a clue for the landscape poems coming into being from interpromoting of feelings and experi‐ences to reflection between landscape and feelings .

Edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin II AT1 receptor

Directory of Open Access Journals (Sweden)

Zhang WW

2017-10-01

Full Text Available Wei-Wei Zhang,1,2 Feng Bai,1 Jin Wang,1 Rong-Hua Zheng,1 Li-Wang Yang,1 Erskine A James,3 Zhi-Qing Zhao1,4 1Department of Physiology, Shanxi Medical University, 2Department of Anesthesiology, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China; 3Department of Internal Medicine, Navicent Health, Macon, 4Department of Basic Biomedical Sciences, Mercer University School of Medicine, Savannah, GA, USA Abstract: Angiotensin II (Ang II is known to be involved in the progression of ventricular dysfunction and heart failure by eliciting cardiac fibrosis. The purpose of this study was to demonstrate whether treatment with an antioxidant compound, edaravone, reduces cardiac fibrosis and improves ventricular function by inhibiting Ang II AT1 receptor. The study was conducted in a rat model of transverse aortic constriction (TAC. In control, rats were subjected to 8 weeks of TAC. In treated rats, edaravone (10 mg/kg/day or Ang II AT1 receptor blocker, telmisartan (10 mg/kg/day was administered by intraperitoneal injection or gastric gavage, respectively, during TAC. Relative to the animals with TAC, edaravone reduced myocardial malonaldehyde level and increased superoxide dismutase activity. Protein level of the AT1 receptor was reduced and the AT2 receptor was upregulated, as evidenced by the reduced ratio of AT1 over AT2 receptor (0.57±0.2 vs 3.16±0.39, p<0.05 and less locally expressed AT1 receptor in the myocardium. Furthermore, the protein level of angiotensin converting enzyme 2 was upregulated. In coincidence with these changes, edaravone significantly decreased the populations of macrophages and myofibroblasts in the myocardium, which were accompanied by reduced levels of transforming growth factor beta 1 and Smad2/3. Collagen I synthesis was inhibited and collagen-rich fibrosis was attenuated. Relative to the TAC group, cardiac systolic function was preserved, as shown by increased left ventricular systolic pressure (204±51 vs 110±19

新春的九华山

Institute of Scientific and Technical Information of China (English)

HelenThompson; SuzanneLeach

2004-01-01

Situated southwest of Qingyang County in Anhui province, Jiuhua Shan, also known as the Nine Brilliant Mountains is one of China's four famous sacred Buddhist Mountains. The mountain was formed in the late Cenozoic Era, and became a Buddhist Mountain in the Northern and Southern Dynasties (420-589). It is said in history that a Korean aristocrat, Jin Qiaojue, came to the mountain and lived in a cave at Dongya peak. His hard practice moved the local people so much that they decided to build a

[Application of fuzzy mathematics on modifying taste of oral solution of traditional Chinese drug].

Science.gov (United States)

Wang, Youjie; Feng, Yi; Zhang, Bo

2009-01-01

To apply Fuzzy mathematical methods to choose the best taste modifying prescription of oral solution of traditional Chinese drug. Jin-Fukang oral solution was used as a model drug. The oral solution was prepared in different taste modifying prescriptions, whose tastes were evaluated by the fuzzy quality synthetic evaluation system. Compound-sweeteners with Sucralose and Erythritol was the best choice. Fuzzy integrated evaluation can be used to evaluate the taste of traditional Chinese medicinal pharmaceuticals, which overcame the artificial factors and achieve more objective conclusion.

Optical closure of apparent optical properties in coastal waters off Goa

Digital Repository Service at National Institute of Oceanography (India)

Talaulikar, M.; Suresh, T.; Desa, E.S.; Inamdar, A.

by manufacturer. The instrument was deployed in “fish out” mode positioning the boat such as to keep the radiometer well under the sun avoiding the boat shadow. Care was taken to deploy the radiometer with tilt less than 5 degrees (Suresh et al. 2012... analytical ocean color model for global-scale applications. Applied Optics, 41, 2705-2714 . Mobley, C. D. (1994). Light and water: radiative transfer in natural waters. Academic Press. Mobley, C. D., Gentili, B., Gordon, H. R., Jin, Z., Kattawar, G...

Targeting Biological Sensing with Commercial SERS Substrates

Science.gov (United States)

2012-09-01

substrate substrate. Sl x 4 mm waf urement to re ossible contam substrates, fiv resented as an e being used f tigated, and nam eived in an ac cations...targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA," Journal of Drug Targeting, 900-914 (2011). [35] Jong , H.J., Na...J.H., Jin, B.S., Lee, W.K., Lee, W.H., Jung, H.J., Kim , S.C., Lim, S.H., Yu, Y.G., "Identification of Dinitrotoluene Selective Peptides by Phage

Eestlased Pekingi biennaalil

Index Scriptorium Estoniae

2005-01-01

20. IX avatud Pekingi II kunstibiennaalist, mille peakuraatoriteks on Jin Shangyi, Liu Dawei ja Feng Yuan. Eestit esindavad biennaalil Leo Lapini maal seeriast "Kood", Jaan Toomiku maal "Mees metsas", Anne-Daniela Saaliste ja Paul Rodgersi kineetiline installatsioon "Karusell". Hefeis toimus IAA (International Association of Art) XVI konverents ja assamblee. IAA uueks esimeheks valiti Liu Dawei Hiinast. Hefei Anmei kunstilinnakus avati 23. VIII näitus peaassambleel esindatud kunstnikeorganisatsioonide delegaatide-kunstnike töödest, kus Eestist oli väljas Jaan Elkeni maal "Preemia"

Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy

Directory of Open Access Journals (Sweden)

Wu JY

2018-03-01

Full Text Available Jun-Yi Wu,1,* Zhong-Xia Wang,1,* Guang Zhang,1 Xian Lu,1 Guang-Hui Qiang,2 Wei Hu,2 An-Lai Ji,3 Jun-Hua Wu,4 Chun-Ping Jiang1 1Department of Hepatobiliary Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China; 2Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China; 3Department of General Surgery, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China; 4Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, Jiangsu, China *These authors contributed equally to this work Purpose: FTY720, known as fingolimod, is a new immunosuppressive agent with effective anticancer properties. Although it was recently confirmed that FTY720 inhibits cancer cell proliferation, FTY720 can also induce protective autophagy and reduce cytotoxicity. Blocking autophagy with Beclin 1 siRNA after treatment with FTY720 promotes apoptosis. The objective of this study was to enhance the anticancer effect of FTY720 in hepatocellular carcinoma (HCC by targeted co-delivery of FTY720 and Beclin 1 siRNA using calcium phosphate (CaP nanoparticles (NPs.Materials and methods: First, the siRNA was encapsulated within the CaP core. To form an asymmetric lipid bilayer structure, we then used an anionic lipid for the inner leaflet and a cationic lipid for the outer leaflet; after removing chloroform by rotary evaporation, these lipids were dispersed in a saline solution with FTY720. The NPs were analyzed by transmission electron microscopy, dynamic light scattering and ultraviolet–visible spectrophotometry. Cancer cell viability and cell death were analyzed by MTT assays, fluorescence-activated cell sorting analysis and Western blotting. In addition, the in vivo effects of the NPs were investigated using an athymic nude mouse subcutaneous transplantation tumor model.Results: When the CaP NPs, called