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Sample records for matthias ketzel steen

  1. Jan Steen 'de kluchtschilder'

    NARCIS (Netherlands)

    Vries, Lyckle de

    1977-01-01

    Diese Arbeit ist den Genrebildern Jan Steens (1629-1679). Der erste Teil enthält eine Auseinandersetzung mit der kunsthistorischen Literatur über Jan Steen. Der dritte Teil enthält einige theoretische Betrachtungen über Jan Steen und siene Stellung in der Geschichte der niederländische Kunst.

  2. Steen Høyer

    DEFF Research Database (Denmark)

    Bogen viser og samler for første gang Steen Høyers arbejder fra de første udstillinger med skulpturelle installationer i 1960'erne over mange års arbejde med collager, mail art og fotografier af by og landskaber, til den lange række af idé-, skitse- og konkurrenceprojekter fra 1970'erne til idag...

  3. Part Twelve. The Voyages of John Matthias

    OpenAIRE

    Printz-Påhlson, Göran

    2013-01-01

    In August 1974, when the Watergate scandal was moving into its last phase, the American poet John Matthias returned to his home, in South Bend, Indiana, after a year’s stay in England, traveling on the Polish ocean-liner Stefan Bathory. In June of 1976 he set out to sea again, this time on a Russian ship, the Mikhail Lermontov, in order to spend another year in England, as a Visiting Fellow in Poetry in Clare Hall, Cambridge. The voyages took approximately nine days each, and on both ships he...

  4. Matthias Neuenhofer: Videos 1988-1995

    DEFF Research Database (Denmark)

    Kacunko, Slavko

    -reflexivity of the medium through the phenomenon of video feedback. Between 1988 and 1995 it built the basis of the video works by Matthias Neuenhofer. The presented essay on his Feedback-Videos completes the monograph-‘video-trilogy’ of Slavko Kacunko, which has begun with the book about Marcel Odenbach (1999...... of intention” (M. Baxandall): These are all characteristics of a named but not yet developed, Infinitesimal Aesthetics which ‘origin’ seems to be the repetition, which again, as much as its ‘goal’ must remain unnamed, at least if the distance to the otherwise impending visual dogmatism and image...... to allow the discovering of Histories, Coincidences, and Infinitesimal Aesthetics inscribed into the Video medium as its unsurpassed topicality. [1] Andreas Breitenstein has used this notion in his review of the book Die Winter im Süden of Norbert Gstrein (2008). In: Neue Zürcher Zeitung, 26. August 2008...

  5. Audru Püha Risti kirik / Jürgen Grablings, Jacob Greisson, Matthias Woywoden...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    välisvaade, altar; kivikirik pühitseti 1680 (ehitusmeistrid Jürgen Grablings, Jacob Greisson, Matthias Woywoden), torn valmis pärast 1695. aastat; neogooti stiilis tornikiiver ja sisustus XIX sajandil; altarimaal "Kristus ristil" (Gustav Biermann, 1872)

  6. Quickly erupted volcanic sections of the Steens Basalt, Columbia River Basalt Group: Secular variation, tectonic rotation, and the Steens Mountain reversal

    Science.gov (United States)

    Jarboe, Nicholas A.; Coe, Robert S.; Renne, Paul R.; Glen, Jonathan M. G.; Mankinen, Edward A.

    2008-01-01

    The Steens Basalt, now considered part of the Columbia River Basalt Group (CRBG), contains the earliest eruptions of this magmatic episode. Lava flows of the Steens Basalt cover about 50,000 km2 of the Oregon Plateau in sections up to 1000 m thick. The large number of continuously exposed, quickly erupted lava flows (some sections contain over 200 flows) allows for small loops in the magnetic field direction paths to be detected. For volcanic rocks, this detail and fidelity are rarely found outside of the Holocene and yield estimates of eruption durations at our four sections of ∼2.5 ka for 260 m at Pueblo Mountains, 0.5 to 1.5 ka for 190 m at Summit Springs, 1–3 ka for 170 m at North Mickey, and ∼3 ka for 160 m at Guano Rim. That only one reversal of the geomagnetic field occurred during the eruption of the Steens Basalt (the Steens reversal at approximately 16.6 Ma) is supported by comparing 40Ar/39Ar ages and magnetic polarities to the geomagnetic polarity timescale. At Summit Springs two 40Ar/39Ar ages from normal polarity flows (16.72 ± ± 0.29 Ma (16.61) and 16.92 ± ± 0.52 Ma (16.82); ± ± equals 2σ error) place their eruptions after the Steens reversal, while at Pueblo Mountains an 40Ar/39Ar age of 16.72 ± ± 0.21 Ma (16.61) from a reverse polarity flow places its eruption before the Steens reversal. Paleomagnetic field directions yielded 50 nontransitional directional-group poles which, combined with 26 from Steens Mountain, provide a paleomagnetic pole for the Oregon Plateau of 85.7°N, 318.4°E, K = 15.1, A95 = 4.3. Comparison of this new pole with a reference pole derived from CRBG flows from eastern Washington and a synthetic reference pole for North America derived from global data implies relative clockwise rotation of the Oregon Plateau of 7.4 ± 5.0° or 14.5 ± 5.4°, respectively, probably due to northward decreasing extension of the basin and range.

  7. 75 FR 10813 - Notice of Public Meetings for the Steens Mountain Advisory Council

    Science.gov (United States)

    2010-03-09

    ...; November 18 and 19, 2010 in Bend, Oregon; and July 1 and 2, 2010 in Diamond, Oregon. All meeting sessions.... The July meeting will be held at the Diamond School on Diamond Lane in Diamond, Oregon. The November... Ecosystem Restoration Project implementation; Science Strategy; South Steens Water Development Project...

  8. Hard-headedness will get you there. Matthias Eggert generates profitable solar power on a south-western roof in Schleswig-Holstein; Mit Sturheit kommt man weiter. Matthias Eggert produziert in Schleswig-Holstein auf einem Suedwestdach rentablen Solarstrom

    Energy Technology Data Exchange (ETDEWEB)

    Krause, Matthias B.

    2011-12-15

    Profitable generation of solar power in northern Germany, on a roof that is not facing south? Home owner Matthias Eggert of Schafstedt in the German region of Dithmarschen decided to give it a try. His solar cell arrays started power generation in 2009, and in 20 years he will have earned nearly 10,000 Euros if things go well.

  9. Consumption patterns and living conditions inside Het Steen, the late medieval prison of Malines (Mechelen, Belgium)

    OpenAIRE

    Troubleyn, L.; Kinnaer, F.; Ervynck, A.; Beeckmans, L.; Caluwé, D.; Cooremans, B.; de Buyser, F.; Deforce, K.; Desender, K.; Lentacker, A.; Moens, J.; Van Bulck, G.; Van Dijck, M.; Van Neer, W.; Wouters, W.

    2009-01-01

    Excavations at the Main Square (Grote Markt) of Malines (Mechelen, Belgium) have unearthed the building remains of a tower, arguably identifiable as the former town prison: Het Steen. When this assumption is followed, the contents of the fills of two cesspits dug out in the cellars of the building illustrate aspects of daily life within the early 14th-century prison. An integrated approach of all find categories, together with the historical context available, illuminates aspects of the mater...

  10. In Anführungszeichen. Glanz und Elend der Political Correctness von Matthias Dusini und Thomas Edlinger

    Directory of Open Access Journals (Sweden)

    Raffaela Rogy

    2014-12-01

    Full Text Available Matthias Dusini und Thomas Edlinger nähern sich in erfrischend lockerem Ton dem Thema Political Correctness (PC, indem sie dessen historisches Gewebe offenlegen, aktuelle Debatten aufzeigen und eigene Überlegungen dazu vorstellen. Raffaela Rogy berichtet.

  11. The Steens Mountain ( Oregon) geomagnetic polarity transition ( USA). 3. Its regional significance.

    Science.gov (United States)

    Mankinen, E.A.; Larson, E.E.; Gromme, C.S.; Prevot, M.; Coe, R.S.

    1987-01-01

    Study of the variations of direction and intensity of the geomagnetic field as recorded by the Miocene lava flows on Steens Mountain, SE Oregon, has resulted in a detailed description of total field behavior during a reversal in polarity. In addition to information about the polarity reversal itself, the detailed paleomagnetic record includes several thousand years of geomagnetic history preceding and following the polarity transition at 15.5 Ma. To test the feasibility of using this record as a means of correlation in this part of the western US, comparisons are made of reconnaissance and previously published paleomagnetic records obtained from what has been thought to be the Steens Basalt or rocks of equivalent age. Despite the fact that many of these earlier studies were not detailed and were not intended for correlation purposes, convincing similarities among some of the records are evident. The Steens Basalt paleomagnetic record does, indeed, have potential as a correlation tool during this time of widespread basaltic volcanism. Concludes that findings indicate no post-20 Ma differential rotation between S-E Washington and S-central Oregon, in contrast to previous interpretations. -from Authors

  12. The age of the Steens reversal and the Columbia River Basalt Group

    Science.gov (United States)

    Jarboe, Nicholas A.; Coe, Robert S.; Renne, Paul R.; Glen, Jonathan M. G.

    2010-01-01

    The Columbia River Basalt Group (CRBG) eruptions have a well-defined relative magnetostratigraphy but have not been definitively correlated to the geomagnetic polarity time scale. 40Ar/39Ar ages are presented from lavas erupted in the R0 through N1magnetozones of the CRBG and in the transition between R0 and N0. Four ages from transitionally magnetized lava flows at Steens Mountain, Catlow Peak, and Poker Jim Ridge with a weighted mean age 16.58 ± 0.10 Ma1 and the more precise age 16.654 ± 0.025 Ma of the normally magnetized Oregon Canyon tuff at the top of the Catlow Peak section show that the oldest CRBG magnetozone (R0) correlates with the C5Cr chron. Bayesian statistical analysis applied to data from four flows at Catlow Peak (using the mean age of the Steens reversal) gives a best and preferred age of the Steens reversal of 16.73 + 0.13/−0.08 Ma (95% confidence). Depending on the geomagnetic polarity time scale model, the eruption rate from N0 through R2 (0.34–0.45 Ma in the middle and the bulk of the CRBG emplacement) averaged 0.30–0.41 km3/a and peaked at a rate 1 1/2 to 4 1/2 times higher during R2.

  13. Jörg Matthias Determann, Historiography in Saudi Arabia: Globalization and the State in the Middle East

    OpenAIRE

    Pétriat, Philippe

    2016-01-01

    It is a widely held view that Saudi Arabia’s history is recent, that its main elements are oil, Salafism and sectarianism, and that this recent history has been written mostly by non-Saudi scholars. In a stimulating in-depth analysis of Saudi historiography on Saudi Arabia, Jörg Matthias Determann delves into the very writing of history. He draws on an impressive range of written (including Saudi and non-Saudi historical works, dissertations, articles and textbooks) as well as oral sources. A...

  14. The genesis of Jan Steens painting 'As the old ones sing, so the young ones pipe' from the Gemaeldegalerie Berlin

    International Nuclear Information System (INIS)

    Denker, A.; Kleinert, K.; Laurenze-Landsberg, C.; Reimelt, M.; Schroeder-Smeibidl, B.

    2011-01-01

    In collaboration with the research reactor of the Helmholtz-Zentrum Berlin fuer Materialien und Energie, the Gemaeldegalerie Berlin is the only institute worldwide, which systematically employs the method of Neutron-Activation-Autoradiography to analyze paintings and painting techniques. To date more than 70 paintings were investigated with this effective, non-destructive, and exceptional method. It allows the visualization of structures and layers beneath the top surface and, in addition, enables the identification of elements contained in the pigments. The instrument B8 at the research reactor BER II is dedicated to this research. Jan Steen is one of the prolific artists from the 17th century. Like other artists from that time he produced several versions of one specific topic during life-time. The topic 'As the old ones sing, so the young ones pipe' was painted by Jan Steen in 13 versions. The painting from the Gemaeldegalerie is an exception in this series as it differs in style and content from the other oeuvres. The question arises: why did the artist deviate from his usual scheme? The possible answer is provided by X-ray images and neutron autoradiographs made of the painting, allowing insight into hidden paint layers and, therefore, in the genesis of the painting. Jan Steen did not simply change the composition of the room and the figures. He originally intended an altogether different topic. Assumedly it was supposed to be a so-called merry company, located in a generous, stately room. Many pieces of this sophisticated ambiance have been eliminated from the version visible today; others were modified and integrated into the composition of the new painting. Thus, Jan Steen commenced the topic 'As the old ones sing, so the young ones pipe' from a different context.

  15. Miocene Basaltic Lava Flows and Dikes of the Intervening Area Between Picture Gorge and Steens Basalt of the CRBG, Eastern Oregon

    Science.gov (United States)

    Cahoon, E. B.; Streck, M. J.

    2016-12-01

    Mid-Miocene basaltic lavas and dikes are exposed in the area between the southern extent of the Picture Gorge Basalt (PGB) and the northern extent of Steens Basalt in a wide corridor of the Malheur National Forest, eastern Oregon. An approximate mid-Miocene age of sampled basaltic units is indicated by stratigraphic relationships to the 16 Ma Dinner Creek Tuff. Lavas provide an opportunity to extend and/or revise distribution areas of either CRBG unit and explore the petrologic transition between them. The PGB and the Steens Basalt largely represent geochemically distinct tholeiitic units of the CRBG; although each unit displays internal complexity. Lavas of PGB are relatively primitive (MgO 5-9 wt.%) while Steens Basalt ranges in MgO from >9 to 3 wt.% but both units are commonly coarsely porphyritic. Conversely, Steens Basalt compositions are on average more enriched in highly incompatible elements (e.g. Rb, Th) and relatively enriched in the lesser incompatible elements (e.g. Y, Yb) compared to the Picture Gorge basalts. These compositional signatures produce inclined and flat patterns on mantle-normalized incompatible trace element plots but with similar troughs and spikes, respectively. New compositional data from our study area indicate basaltic lavas can be assigned as PGB lava flows and dikes, and also to a compositional group chemically distinct between Steens Basalt and PGB. Distribution of lava flows with PGB composition extend this CRBG unit significantly south/southeast closing the exposure gap between PGB and Steens Basalt. We await data that match Steens Basalt compositions but basaltic lavas with petrographic features akin to Steens Basalt have been identified in the study area. Lavas of the transitional unit share characteristics with Upper Steens and Picture Gorge basalt types, but identify a new seemingly unique composition. This composition is slightly more depleted in the lesser incompatible elements (i.e. steeper pattern) on mantle normalized

  16. Meeting the challenge of future energy supply from the perspective of Royal Dutch Shell. An interview with Matthias Bichsel

    Energy Technology Data Exchange (ETDEWEB)

    Bollinger, D. (ed.); Gunzenhauser, B. [Vice-President of the Association of Swiss Petroleum Geologists and Engineers, c/o Interoil AG, Zuerich (Switzerland)

    2009-07-01

    In this comprehensive interview in the Swiss Bulletin for Practical Geology with Matthias Bichsel, Director of Projects and Technology at Royal Dutch Shell plc, the subject of 'Peak Oil' is discussed. The question is asked on how Shell deals with the fact that oil and gas resources are limited and sooner or later will be more or less depleted or can only be used at high cost. A further topic discussed deals with how Shell wants to satisfy current shareholder interests. At the same time the company needs to be led into a viable and successful future. Shell's efforts to position itself in this difficult situation are discussed. The development of resource estimates, environmental responsibility and sustainability are further topics examined. Current scenarios are looked at and how Shell aims to solve the dilemma of meeting doubling energy demand is discussed. Finally, new technologies and renewable alternatives are looked at

  17. Investigating the response of biotite to impact metamorphism: Examples from the Steen River impact structure, Canada

    Science.gov (United States)

    Walton, E. L.; Sharp, T. G.; Hu, J.; Tschauner, O.

    2018-01-01

    Impact metamorphic effects from quartz and feldspar and to a lesser extent olivine and pyroxene have been studied in detail. Comparatively, studies documenting shock effects in other minerals, such as double chain inosilicates, phyllosilicates, carbonates, and sulfates, are lacking. In this study, we investigate impact metamorphism recorded in crystalline basement rocks from the Steen River impact structure (SRIS), a 25 km diameter complex crater in NW Alberta, Canada. An array of advanced analytical techniques was used to characterize the breakdown of biotite in two distinct settings: along the margins of localized regions of shock melting and within granitic target rocks entrained as clasts in a breccia. In response to elevated temperature gradients along shock vein margins, biotite transformed at high pressure to an almandine-Ca/Fe majorite-rich garnet with a density of 4.2 g cm-3. The shock-produced garnets are poikilitic, with oxide and silicate glass inclusions. Areas interstitial to garnets are vesiculated, in support of models for the formation of shock veins via oscillatory slip, with deformation continuing during pressure release. Biotite within granitic clasts entrained within the hot breccia matrix thermally decomposed at ambient pressure to produce a fine-grained mineral assemblage of orthopyroxene + sanidine + titanomagnetite. These minerals are aligned to the (001) cleavage plane of the original crystal. In this and previous work, the transformation of an inosilicate (pargasite) and a phyllosilicate (biotite) to form garnet, an easily identifiable, robust mineral, has been documented. We contend that in deeply eroded astroblemes, high-pressure minerals that form within or in the environs of shock veins may serve as one of the possibly few surviving indicators of impact metamorphism.

  18. The Steens Mountain (Oregon) geomagnetic polarity transition: 1. Directional history, duration of episodes, and rock magnetism

    Science.gov (United States)

    Mankinen, Edward A.; Prevot, M.; Gromme, C. Sherman; Coe, Robert S.

    1985-01-01

    The thick sequence of Miocene lava flows exposed on Steens Mountain in southeastern Oregon is well known for containing a detailed record of a reversed‐to‐normal geomagnetic polarity transition. Paleomagnetic samples were obtained from the sequence for a combined study of the directional and intensity variations recorded; the paleointensity study is reported in a companion paper. This effort has resulted in the first detailed history of total geomagnetic field behavior during a reversal of polarity. A comparison of the directional variation history of the reversed and normal polarity intervals on either side of the transition with the Holocene record has allowed an estimate of the duration of these periods to be made. These time estimates were then used to calculate accumulation rates for the volcanic sequence and thereby provide a means for estimating time periods within the transition itself. The polarity transition was found to consist of two phases, each with quite different characteristics. At the onset of the first phase, a one‐third decrease in magnetic field intensity may have preceded the first intermediate field directions by about 600 years. Changes in field direction were confined near the local north‐south vertical plane when the actual reversal in direction occurred and normal polarity directions may have been attained within 550±150 years. The end of the first phase of the transition was marked by a brief (possibly 100–300 years) period with normal polarity and a pretransitional intensity which suggests a quasi‐normal dipole field structure existed during this interval. The second phase of the transition was characterized by a return to very low field intensities with the changes in direction describing a long counterclockwise loop in contrast to the earlier narrowly constrained changes. This second phase lasted 2900±300 years, and both normal directions and intensities were recovered at the same time. Both directional and intensity

  19. Evidence from lava flows for complex polarity transitions: The new composite Steens Mountain reversal record

    Science.gov (United States)

    Jarboe, Nicholas A.; Coe, Robert S.; Glen, Jonathan M. G.

    2011-01-01

    Geomagnetic polarity transitions may be significantly more complex than are currently depicted in many sedimentary and lava-flow records. By splicing together paleomagnetic results from earlier studies at Steens Mountain with those from three newly studied sections of Oregon Plateau flood basalts at Catlow Peak and Poker Jim Ridge 70–90 km to the southeast and west, respectively, we provide support for this interpretation with the most detailed account of a magnetic field reversal yet observed in volcanic rocks. Forty-five new distinguishable transitional (T) directions together with 30 earlier ones reveal a much more complex and detailed record of the 16.7 Ma reversed (R)-to-normal (N) polarity transition that marks the end of Chron C5Cr. Compared to the earlier R-T-N-T-N reversal record, the new record can be described as R-T-N-T-N-T-R-T-N. The composite record confirms earlier features, adds new west and up directions and an entire large N-T-R-T segment to the path, and fills in directions on the path between earlier directional jumps. Persistent virtual geomagnetic pole (VGP) clusters and separate VGPs have a preference for previously described longitudinal bands from transition study compilations, which suggests the presence of features at the core–mantle boundary that influence the flow of core fluid and distribution of magnetic flux. Overall the record is consistent with the generalization that VGP paths vary greatly from reversal to reversal and depend on the location of the observer. Rates of secular variation confirm that the flows comprising these sections were erupted rapidly, with maximum rates estimated to be 85–120 m ka−1 at Catlow and 130–195 m ka−1 at Poker Jim South. Paleomagnetic poles from other studies are combined with 32 non-transitional poles found here to give a clockwise rotation of the Oregon Plateau of 11.4°± 5.6° with respect to the younger Columbia River Basalt Group flows to the north and 14.5°± 4.6° with respect

  20. Sundby Mors mellem dynamik og tradition. Opposition mod Steen Buscks disputats Et landbosamfund i opbrud. Sundby Mors 1660-1800, 2011.

    Directory of Open Access Journals (Sweden)

    Carsten Porskrog Rasmussen

    2012-05-01

    Full Text Available Opposition to Steen Busck’s Doctoral Thesis A Rural Community Breaking Up. Tradition and Modernization in Sundby Parish on the Island of Mors during the Period 1660-1800, vol. 1-2, Aarhus, 2011. A central feature of Steen Busck’s dissertation is the concept of a “traditional” rural community, which not until late in the period embarks seriously on a “modernization”, which to the author is synonymous with the introduction of capitalism. The present opposition will discuss this theory, taking as its point of departure a number of concrete manifestations of it in Steen  Busck’s book. The emphasis is on the economic side, which also, when all is said and done, is the mainstay of Busck’s theory. Steen Busck attempts to demonstrate that the economy was relatively stagnant and oriented towards self-sufficiency, and that the market economy only penetrated slowly. The opposition discusses various indications of how agriculture developed during the period, and it is argued that there was a larger degree of development than is assumed by Busck. Simultaneously, the balance between self-sufficiency and market economy is discussed, including some of the farmers’ budgets that Busck has constructed. The opponent argues that production was fairly evenly organized for self-sufficiency and for the market, and he draws attention to the enterprising cattle-dealers who have been found by Steen Busck but to whom he ascribes no decisive importance. The last part of the opposition deals with the relationship between the landed estates, the property market and the power of the state. Here it is argued that Sundby was an atypical parish as far as the estate structure was concerned, since it was dominated by scattered farms which frequently changed hands, being sold from one landed estate to another. This implies that Steen Busck’s theory of the property market helping to destroy the estate as an institution and paving the way for agricultural reforms

  1. [Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen : Stadt, Land und Konfession 1500-1721. Teil 4. Hrsg. von Matthias Asche, Werner Buchholtz und Anton Schindlin

    Index Scriptorium Estoniae

    Maasing, Madis, 1984-

    2013-01-01

    Arvustus: Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen : Stadt, Land und Konfession 1500-1721. Teil 4. (Katholisches Leben und Kirchenreform im Zeitalter der Glaubensspaltung, 72). Hrsg. von Matthias Asche, Werner Buchholtz und Anton Schindling. Verlag Aschendorff. Münster 2012

  2. [Matthias Asche, Werner Buchholz, Anton Schindling. Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen; Stadt, Land und Konfession 1500-1721. T. 1-3] / Axel von C

    Index Scriptorium Estoniae

    Campenhausen, Axel von

    2015-01-01

    Arvustus: Asche, Matthias, Bucholz, Werner, Achindling, Anton. (Hrsg.) Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen; Stadt, Land und Konfession 1500-1721. T. 1-3. Münster: Aschendorff Verlag 2009, 2010, 2011

  3. Review of Calculation vs. Context: Quantitative Literacy and Its Implications for Teacher Education by Bernard L. Madison and Lynn Arthur Steen (Editors

    Directory of Open Access Journals (Sweden)

    Maura B. Mast

    2009-07-01

    Full Text Available Madison, Bernard L. and Steen, Lynn Arthur (Eds.. Calculation vs. Context: Quantitative Literacy and Its Implications for Teacher Education. (Washington, DC: Mathematical Association of America, 2009. 197 pp. Softcover. ISBN 978-0-88385-908-7. Available free on the MAA website at http://www.maa.org/ql/calcvscontext.htmlThe papers in Calculation vs. Context discuss the role of quantitative literacy in the K-12 curriculum and in teacher education. The papers present a varied set of perspectives and address three themes: the changing environment of education in American society; the challenges, and the necessity, of preparing teachers to teach quantitative literacy and of including quantitative literacy in the K-12 education; and cross-disciplinary approaches to quantitative literacy. While the conclusion reached by several of the authors is that the best place to teach quantitative literacy is at the college level, the book offers serious considerations of how quantitative literacy can and should inform the K-12 curriculum. The book also marks a turning point in the quantitative literacy movement as “QL explorers,” as Lynn Steen calls them, move beyond issues of definitions and content to a discussion of how to bring quantitative literacy into a broader setting.

  4. Geradeheraus / Matthias Nöther

    Index Scriptorium Estoniae

    Nöther, Matthias

    2008-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle. Esietendus 17. oktoobril 2008 Tallinnas Rahvusooperis Estonia

  5. „Tenke det, ønske det, ville det med – men gjøre det! ...”. Opposisjonsinnlegg ved Steen Buscks disputatsforsvar ved Aarhus Universitet 25. november 2011 med avhandlingen Et landbosamfund i opbrud. Sundby Mors 1660-1800, 2011.

    Directory of Open Access Journals (Sweden)

    Finn-Einar Eliassen

    2012-05-01

    Full Text Available English summary Steen Busck’s doctoral dissertation, Et landbosamfund i opbrud (A Rural Community Breaking etc., is a detailed and  well-documented study of the parish of Sundby Mors in Northern Jutland in the period 1660-1800. The author analyses all aspects of this small, rural community of some 200 inhabitants in the late eighteenth century – landscape, demography, social structure, economy, administration, culture and mentality, drawing on his wide knowledge and reading, as well as nearly all available sources in public archives, to produce a very solid local history of Sundby Mors in two volumes, with nearly 1200 pages. It is a monumental work, in more than one sense. According to Busck himself, the study should be a total history, local history, microhistory and a case study of an early modern agricultural community. Although overlapping to a certain extent, these labels point in different directions, but the author does not make an effort to distinguish between them. Claiming that his purpose is to find ”typical” elements in a local society which he claims is unique, and using methods which are not comparative or synthetic, but rather descriptive and individualistic, he gets into difficulties when he tries to draw general conclusions. Steen Busck’s main question is whether the parish of Sundby Mors underwent any "modernisation” dusring the studied period. However, his definitions of a "traditional” and a "modern” society represent extreme models, which would be hard to find in the real world, and so he concludes that Sundby Mors failed to modernise, although he finds changes and developments in many different fields, which seem to warrant a more nuanced conclusion. Also, his sources, which are mainly official records, are heavily weighted in favour of traditional agriculture and resident population, more likely to show stabilty than change.  And although Steen Busck draws on other local studies in  analysing the

  6. „Tenke det, ønske det, ville det med – men gjøre det! ...”. Opposisjonsinnlegg ved Steen Buscks disputatsforsvar ved Aarhus Universitet 25. november 2011 med avhandlingen Et landbosamfund i opbrud. Sundby Mors 1660-1800, 2011.

    Directory of Open Access Journals (Sweden)

    Finn-Einar Eliassen

    2012-05-01

    Full Text Available English summarySteen Busck’s doctoral dissertation, Et landbosamfund i opbrud (A Rural Community Breaking etc., is a detailed and  well-documented study of the parish of Sundby Mors in Northern Jutland in the period 1660-1800. The author analyses all aspects of this small, rural community of some 200 inhabitants in the late eighteenth century – landscape, demography, social structure, economy, administration, culture and mentality, drawing on his wide knowledge and reading, as well as nearly all available sources in public archives, to produce a very solid local history of Sundby Mors in two volumes, with nearly 1200 pages. It is a monumental work, in more than one sense. According to Busck himself, the study should be a total history, local history, microhistory and a case study of an early modern agricultural community. Although overlapping to a certain extent, these labels point in different directions, but the author does not make an effort to distinguish between them. Claiming that his purpose is to find ”typical” elements in a local society which he claims is unique, and using methods which are not comparative or synthetic, but rather descriptive and individualistic, he gets into difficulties when he tries to draw general conclusions.Steen Busck’s main question is whether the parish of Sundby Mors underwent any "modernisation” dusring the studied period. However, his definitions of a "traditional” and a "modern” society represent extreme models, which would be hard to find in the real world, and so he concludes that Sundby Mors failed to modernise, although he finds changes and developments in many different fields, which seem to warrant a more nuanced conclusion. Also, his sources, which are mainly official records, are heavily weighted in favour of traditional agriculture and resident population, more likely to show stabilty than change.  And although Steen Busck draws on other local studies in  analysing the different

  7. [Walter Matthias Diggelmann--the healing effect of story telling].

    Science.gov (United States)

    Schmid, H J

    2001-06-21

    "Stories are weapons against disease" wrote Swiss writer WM Diggelmann (1927-1979). In writing stories he hoped to counteract the lethal course of his cancer. In the past it had helped him to overcome destitution and social disgrace and had given him identity. His last story Walking on the Island of St. Margaret is a ritual which conjures up an intact future by celebrating the past. Stories try to explain the world. They inform or clarify emotions. In telling stories, doctors and nurses demonstrate sympathy and understanding. Perhaps even greater benefits might be derived from patients telling their own stories. In doing so they emerge as individuals and give their lives purpose. Language is more than communication: it is shelter, link, home, ritual. Storytelling helps patients cope with their diseases. It is not clear whether this or any technique of psychotherapy has any effect upon the course of cancer.

  8. Transforming controversy into consensus: the Steens Mountain initiative

    Science.gov (United States)

    Steven W. Anderson

    1995-01-01

    Even bitterly disputed management issues can be tempered or eliminated. Agency outreach efforts in conjunction with the media, working groups, effected interests, field trips, and "open house" social events can result in unified management efforts. In addition, distortions or misconceptions can be clarified. Recurrent efforts are required to build good...

  9. Imidacloprid of niet? (interview met Sjef van der Steen)

    NARCIS (Netherlands)

    Kleis, R.; Steen, van der J.J.M.

    2014-01-01

    Is bijensterfte het werk van neonicotinoïden? Ja, zeggen en denken velen. Volgens hen zijn de neo’s rechtstreeks verantwoordelijk voor de hoge sterfte onder bijen. Nee, toont Wagenings onderzoek aan. Intussen lijkt het met de sterfte voorzichtig de goede kant op te gaan.

  10. 77 FR 66478 - Steens Mountain Advisory Council; Meetings

    Science.gov (United States)

    2012-11-05

    ... Management Plan; and planning future meeting agendas, dates, and locations. Any other matters that may... prior to the session. Meeting dates, times, locations, and the duration scheduled for public comment... accommodate necessary business and all who seek to be heard regarding matters before the SMAC. FOR FURTHER...

  11. Waer een steen so breet dat hi al eertrijck besloech

    DEFF Research Database (Denmark)

    Robbe, Joost Roger

    2014-01-01

    and Vliederhoven’s and Van Rijkel’s Latin versions can only be explained by the influence of the Middle Dutch translation of the Horologium, whereby the transition from ‘zadeken’ (seed) to ‘zandeken’ (sand) in the Middle Dutch translation led to the introduction of a sand stone or sand mount in the versions...... of Vliederhoven and Van Rijkel respectively. In this way, the reception of Suso’s allegory in the Netherlands in the 15th century represents an illuminative example of how Latin texts could both influence and be influenced by vernacular literature....

  12. Menschenrechtliche Vorgaben an das Aufenthaltsrecht in der jüngeren Rechtsprechung des EGMR / Matthias Lehnert

    Index Scriptorium Estoniae

    Lehnert, Matthias

    2016-01-01

    Inimõiguste konventsiooni (eelkõige artiklite 3 ja 8) tõlgendamisest asüülitaotlejate kohtlemisel ELi liikmesriikides; Euroopa Inimõiguste Kohtu vastavast praktikast (nt Tarakhel vs. Šveits; V.M. vs. Belgia; Mohammed vs. Austria, Khan vs. Saksamaa)

  13. Freies Geleit für Edward Snowden? / Matthias Friehe, Christopher Lipp

    Index Scriptorium Estoniae

    Friehe, Matthias

    2014-01-01

    Parlamendi uurimiskomisjoni ette kutsutavate tunnistajate julgeoleku tagamisest Edward Snowdeni juhtumi põhjal; kurjategija väljaandmiskohustusest ja tema karistuse käsitlusest Saksa karistusseadustiku järgi

  14. Comment on 'Modeling of Convective-Stratiform Precipitation Processes: Sensitivity to Partitioning Methods' by Matthias Steiner

    Science.gov (United States)

    Lang, Steve; Tao, W.-K.; Simpson, J.; Ferrier, B.

    2003-01-01

    Despite the obvious notion that the presence of hail or graupel is a good indication of convection, the model results show this does not provide an objective benchmark partly due to the unrealistic presence of small amounts of hail or graupel throughout the anvil in the model but mainly because of the significant amounts of hail or graupel, especially in the tropical TOGA COARE simulation, in the transition zone. Without use of a "transition" category, it is open to debate as how this region should best be defined, as stratiform or as convective. So, the presence of significant hail or graupel contents in this zone significantly degrades its use an objective benchmark for convection. The separation algorithm comparison was done in the context of a cloud-resolving model. These models are widely used and serve a variety of purposes especially with regard to retrieving information that cannot be directly measured by providing synthetic data sets that are consistent and complete. Separation algorithms are regularly applied in these models. However, as with any modeling system, these types 'of models are constantly being improved to overcome any known deficiencies and make them more accurate representations of observed systems. The presence of hail and graupel in the anvil and the bias towards heavy rainfall rates are two such examples of areas that need improvement. Since, both of these can effect the perceived performance of the separation algorithms, the Lang et al. (2003) study did not want to overstate the relative performance of any specific algorithms.

  15. 76 FR 65531 - Notice of Availability of the Final Environmental Impact Statement for the North Steens...

    Science.gov (United States)

    2011-10-21

    ... . SUPPLEMENTARY INFORMATION: The applicant, Echanis, LLC, has filed applications for rights-of-way (ROWs) with the... Cooperative's existing transmission system near Diamond Junction, Oregon. A Draft EIS analyzing impacts of the... near Diamond Junction, Oregon. Included in the analysis of this alternative are two additional minor...

  16. Constitutional pluralism as mutually assured discretion: The Court of Justice, the German Federal Constitutional Court, and the ECB / Matthias Goldmann

    Index Scriptorium Estoniae

    Goldmann, Matthias

    2016-01-01

    Euroopa Kohtu poolt Gauweiler'i kaasuses rakendatud ülevaate standardist, mis puudutasid Euroopa Keskpana (ECB) rahalisi otsetehinguid (OMT). Euroopa Kohtu vaatenurgast ratsionaalsusele ja proportsionaalsusele, mis kannab suurt potentsiaali Euroopa Liidu pluralismile

  17. Nord Stream : täidame kõik Eesti nõudmised / Matthias Warnig ; interv. Jan Jõgis-Laats

    Index Scriptorium Estoniae

    Warnig, Matthias

    2007-01-01

    Nord Streami tegevdirektor pakub võimalust, et Eesti esindajad viibiksid gaasitrassi uuringutel, samuti võivad esindajad teha ette teatamata reide. Firma on valmis arutama kõike, mis on vajalik protsessi kontrollimiseks ja usalduse tekitamiseks

  18. 75 FR 41514 - Notice of Availability of the Draft Environmental Impact Statement for the Proposed North Steens...

    Science.gov (United States)

    2010-07-16

    ...) Public services and transportation; (7) Recreation and tourism; (8) Social and economic effects; and (9... and any other public involvement activities at least 15 days in advance through public notices, media... the media, mailings, and the BLM Web site. Public meetings were held in Burns, Bend, Frenchglen, and...

  19. 77 FR 514 - Notice of Availability of the Record of Decision for the North Steens 230 Kilovolt Transmission...

    Science.gov (United States)

    2012-01-05

    ... subsidiary of Columbia Energy Partners, LLC, filed right-of-way (ROW) applications for ROWs with the BLM and... transmission system near Diamond Junction, Oregon. The ROD approves the BLM-preferred Alternative, now the... Project substation, south of Diamond, Oregon and connect to Harney Electric Cooperative's existing 115-kV...

  20. Rumsansning mellem vane og oplevelse

    DEFF Research Database (Denmark)

    Reeh, Henrik

    2004-01-01

    Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom......Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom...

  1. Symposium „The incorporation of Crimea by the Russian Federation in the light of international law” / Christian Marxen ; Anne Peters ; Matthias Hartwig

    Index Scriptorium Estoniae

    Marxen, Christian

    2015-01-01

    Krimmi kriisist ja Ukraina-Venemaa konfliktist rahvusvahelise õiguse tähenduses 3.-4. septembril 2014 Heidelbergis toimunud konverentsi materjalide põhjal. Teemat käsitlevad artiklid (10) erinevatelt autoritelt.

  2. "Eesti lood" kõrvaltvaates. EDNi direktori Tue Steen Mülleri märkmed 2. veebruaril 2005 toimunud seminaril / Kristiina Davidjants

    Index Scriptorium Estoniae

    Davidjants, Kristiina, 1974-

    2005-01-01

    European Documentary Network'i direktori töötoast ETV ja EFSA dokfilmide sarja "Eesti lood" produtsentidele ja režissööridele. Näitlikult analüüsiti Liina Trishkina filmi "Elluastujad",Õnne Luha "Osta elevant ära", Madli Lääne filmi "Sensatsiooniline Tartu kevadbänd", Arvo Iho "Marina Kuvaitseva ja üksildased naised" ja Mart Taevere "Teistmoodi tihane"

  3. "Eesti lood" - kiiduväärt ettevõtmine / Tue Steen Müller ; tõlk. Marje Jurtšenko

    Index Scriptorium Estoniae

    Müller, Tue Steen

    2004-01-01

    Euroopa dokumentalistika ekspert arvustab kuut 2003.a. tõsielufilmi sarjast "Eesti lood" : "Mees, kes avab uksi" (režii Igor Ruus), "Naeratavad naised" ja "Tuleproov" (Liina Trishkina), "Konfiskeeritud" (Asko Kase), "Järelevalveinspektor" (Madli Lääne), "Hunt" (Priit Valkna)

  4. Appetit på mere

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2014-01-01

    Anmeldelse af Steen Elsborg & Steen Høyrup Pedersens "Folkeoplysning og motivation for livslang læring..", hvor modeller for kortuddannedes ønske om mere uddannelse præsenteres på baggrund af empiriske arbejder...

  5. Matthias Asche, Werner Buchholz, Anton Schindling (Hrsg.): Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung. Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen. Stadt, Land und Konfession 1500-1721. Tl. 2, Münste

    Index Scriptorium Estoniae

    Wittram, Heinrich, 1931-

    2011-01-01

    Arvustus: Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung : Livland, Estland, Ösel, Ingermanland, Kurland und Lettgallen : Stadt, Land und Konfession 1500-1721. Teil 2. Münster, 2010

  6. Review: Oliver Märker & Matthias Trénel (Eds. (2003. Online-Mediation. Neue Medien in der Konfliktvermittlung – mit Beispielen aus Politik und Wirtschaft [Online-Mediation. New Media in Conflict Resolution—with Examples from Politics and Industry

    Directory of Open Access Journals (Sweden)

    Nicola Döring

    2004-01-01

    Full Text Available Online-Mediation deals with conflict resolution methods that are carried out partially or completely online. The book analyses online mediation as a socio-technical system through the means of the computer-based technological platform deeply interwoven with conflict-related social communication. The first part of the book discusses the multiple options and restrictions of online communication in moderation and mediation processes. For example, one advantage of online mediation is that geographically separated parties (e.g. in e-commerce settings can resolve conflicts at comparatively low cost. The second part of the book reports online mediation examples from politics and industry. Although online mediation is described as a seminal method increasingly requested, several socio-technical problems need to be addressed by further research. The book provides an informative view of the subject, focusing on the German-speaking countries. Unfortunately, it lacks a systematic comparison of different online mediation tools and techniques as well as a closer look at the business models and professional issues in this new field of activity. URN: urn:nbn:de:0114-fqs040168

  7. Review: Oliver Märker & Matthias Trénel (Eds.) (2003). Online-Mediation. Neue Medien in der Konfliktvermittlung – mit Beispielen aus Politik und Wirtschaft [Online-Mediation. New Media in Conflict Resolution—with Examples from Politics and Industry

    OpenAIRE

    Nicola Döring

    2004-01-01

    Online-Mediation deals with conflict resolution methods that are carried out partially or completely online. The book analyses online mediation as a socio-technical system through the means of the computer-based technological platform deeply interwoven with conflict-related social communication. The first part of the book discusses the multiple options and restrictions of online communication in moderation and mediation processes. For example, one advantage of online mediation is that geograp...

  8. 專論/從柏林國立圖書館東亞部看德國國家東亞研究資料資源/考恩 | The East Asia Department of the Berlin State Library: German National Resources for East Asian Materials / Matthias Kaun

    Directory of Open Access Journals (Sweden)

    考恩

    2007-10-01

    Full Text Available

    For more than 50 years the East Asia Department of the Berlin State Library has been hosting a special interest collection on East- and Southeast Asia. Integrated into a federal network of German libraries, supervised and in part financed by the German Research Foundation (DFG – Deutsche Forschungsgemeinschaft, this collection has become the largest of its kind in Europe. The East Asia Department supplies German and European libraries with publications in East Asian languages through a special inter-library loan service. Since 2002 the Berlin State Library has offered access to electronic resources like databases and electronic journals from the East Asian region via the virtual library CrossAsia. Furthermore the East Asia Department has become an access point to East Asian databases for European consortia.

    頁次:9-18

  9. Verzorgende ouder of strenge vader : Morele metaforen in Amerikaanse politiek

    NARCIS (Netherlands)

    Renardel de Lavalette, K.; Burgers, C.; Steen, G.

    2016-01-01

    Het taalgebruik van de Amerikaanse presidentskandidaten Hillary Clinton en Donald Trump laat hun morele overtuigingen zien. Hun elkaar ogenschijnlijk uitsluitende metaforen verraden een Verzorgende ouder of een Strenge vader. Kiki Renardel de Lavalette, Christian Burgers en Gerard Steen onderzochten

  10. "Man skal altid gå tilbage til en fuser"

    DEFF Research Database (Denmark)

    Larsen, Steen Nepper

    2012-01-01

    Anmeldelse af Center for Vild Analyse. Brian Benjamin Hansen, Rasmus Ugilt, Steen Thykjær, Kasper Porsgaard, Henrik Jøker Bjerre: Særklasse. Den tøvende revolution, Informations Forlag, 2012, 203 sider......Anmeldelse af Center for Vild Analyse. Brian Benjamin Hansen, Rasmus Ugilt, Steen Thykjær, Kasper Porsgaard, Henrik Jøker Bjerre: Særklasse. Den tøvende revolution, Informations Forlag, 2012, 203 sider...

  11. Why do science in space? Researchers' Night at CERN 2017

    CERN Multimedia

    Nellist, Clara

    2017-01-01

    Space topic and debate "Why do science in space?" With the special presence of Matthias Maurer, European Space Agency astronaut, and Mercedes Paniccia, PhD, Senior Research Associate for space experiment AMS.

  12. Herkommer zum Hinschauen

    OpenAIRE

    Schilling, Jörg

    2011-01-01

    Tagung: Moderne Architektur exemplarisch. Hans Herkommer (1887-1956). Technische Universität Kaiserslautern, Lehrgebiet Geschichte und Theorie der Architektur. Prof. Dr. phil. Matthias Schirren. 28.-29. Oktober 2010

  13. [Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung. Livland, Estland, Ösel, Ingermanland, Kurland und Letgallen. Stadt, Land und Konfession 1500-1721. 2. und 3. Teil] / Anti Selart

    Index Scriptorium Estoniae

    Selart, Anti, 1973-

    2012-01-01

    Arvustus: Die baltischen Lande im Zeitalter der Reformation und Konfessionalisierung. Livland, Estland, Ösel, Ingermanland, Kurland und Letgallen. Stadt, Land und Konfession 1500-1721. Hrsg. von Matthias Asche, Werner Buchholz, Anton Schindling. 2. und 3. Teil.

  14. 57. Baltisches Historikertreffen : vom 5. bis 6. Juni 2004 in Göttingen

    Index Scriptorium Estoniae

    2004-01-01

    57. balti ajaloolaste kohtumisel 5.-6. juunini 2004 esinesid ettekannetega Erki Tammiksaar, Tiit Rosenberg, Olaf Mertelsmann, Klaus Neitmann, Matthias Thumsen, Ilgvars Misans, Henrik Bolte, Thomas Brück, Juhan Kreem, Dieter Heckmann, Stefan Hartmann. Ettekannete kokkuvõtted

  15. Mismoodi on see noorte seis? Ei seisa nigu ... / Pille Runnel

    Index Scriptorium Estoniae

    Runnel, Pille, 1974-

    2015-01-01

    Eraklikest Jaapani hikikomori noortest ja Lõuna-Korea professionaalsetest arvutimängureist kõnelevatest filmidest Maailmafilmi programmis - "Hikikimori, vaikust kuulates" (rež. Dorothée Lorang ja David Beautru), Prantsusmaa-Jaapan ja "Mänguseis" (rež. Steen Dhoedt), Belgia-Korea

  16. Combining Performance and Flexibility for RMS with a Hybrid Architecture

    NARCIS (Netherlands)

    Dennis Koole; Arjan Groenewegen; Daniël Telgen; Patrick Wit; Leo van Moergestel; Arjan van Zanten; John-Jules Meyer; Ing. Erik Puik; Dick van der Steen; Pascal Muller

    2013-01-01

    Author supplied Combining Performance and Flexibility for RMS with a Hybrid Architecture Dani¨el Telgen 12? , Leo van Moergestel 1 , Erik Puik 1 , Pascal Muller 1 , Arjan Groenewegen 1 , Dick van der Steen 1 , Dennis Koole 1 , Patrick de Wit 1 , Arjen van Zanten 1 , and John-Jules

  17. Promoter2.0: for the recognition of PolII promoter sequences

    DEFF Research Database (Denmark)

    Knudsen, Steen; Knudsen, Steen

    1999-01-01

    transcription start sites. On standardized test setsconsisting of human genomic DNA, the performance of Promoter2.0 compares well with other softwaredeveloped for the same purpose. Availability : Promoter2.0 is available as a Web server at http://www.cbs.dtu.dk/services/promoter/ Contact : steen@cbs.dtu.dk...

  18. Neueste Forschung in musiktherapeutischer Diagnostik

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2012-01-01

    responsivem Verhalten. In der Musiktherapie sind mehrere Assessmentmodelle entwickelt worden, unter anderem der IAP von Kenneth Bruscia, AQR von Karin Schumacher und Claudine Calvet-Kruppa oder das Assessment von Kontaktniveaus bei Anne Steen. Nach dieser Einführung des Assessmentbegriffes werden zusätzlich...

  19. Infinite Dimensional Dynamical Systems and their Finite Dimensional Analogues.

    Science.gov (United States)

    1987-01-01

    Rolla ____t___e ___o, __.Paul Steen Cornell Univ.Andrew Szeri Cornell Univ. ByEdriss Titi Univ. of Chicago _Distributi-on/ -S. Tsaltas Unvcrsity of...Cornell University Ithaca, NY 14853 Edriss Titi University of Chicago Dept. of Mathematics 5734 S. University Ave.Chicago, IL 60637 Spiros Tsaltas Dept

  20. Bon appétit! : Hoe onder Napoleon koken een kunst werd

    NARCIS (Netherlands)

    Gabriëls, A.J.C.M.

    2018-01-01

    Het is tegenwoordig moeilijk voor te stellen, maar ooit was Parijs berucht om de slechte kwaliteit van de in herbergen en eethuizen geserveerde maaltijden. Buitenlandse reizigers klaagden hierover steen en been, evenals over de onaangename omstandigheden waaronder het voedsel moest worden genuttigd.

  1. Kunsten at skrive dagbog

    DEFF Research Database (Denmark)

    2009-01-01

    Introduktion og redaktion af tematillæg om dagbøger og dagbogslitteratur, med bidrag af Karsten Sand Iversen, Søren Mogensen Larsen, Steen Klitgård Povlsen, Jacob Lund, Jens Blendstrup, Pablo Llambías og optryk af en samtale fra 1972 mellem Walter Höllerer, Uwe Johnson, Max Frisch, Elias Canetti og...

  2. The Coast Artillery Journal. Volume 85, Number 6, November-December 1942

    Science.gov (United States)

    1942-12-01

    1.00 War and Peace. By Leon Tolstoy , .. , 3.00 Flamingo Road. By Robert lr’ilder . , 2.50 The Sun Is My Undoing. By Marguerite Steen , 3.00 Botany...car, mainte- nance and lubrication. The epidemic of inhuman warfare from which the world is now suffering is destined to be of long dura - tion

  3. Træernes rolle i et landbrugslandskab i Senegal

    DEFF Research Database (Denmark)

    Pedersen, Jens Christian

    2010-01-01

    Ved at gå ind i et eksisterende projektsamarbejde er det lykkedes Steen Christensen at gennemføre et vellykket feltarbejde i Senegal inden for et 6-måneders speciale. Resultaterne fra projektet vil kunne indgå som grundlag for en lokal forvaltning som tager sigte på at beskytte træerne som er en...

  4. Leadership decisions that shaped the destiny of Genzyme: Lessons from 30 years of entrepreneurial leadership: critical decisions for growth

    NARCIS (Netherlands)

    van der Steen, Marianne; Englis-Danskin, Paula

    2011-01-01

    This article is based on an interview of Marianne van der Steen with Henri Termeer‐the long time CEO of Genzyme. Within Europe, Genzyme’s state-of-the-art cell culture production facility for therapeutic proteins is located in Geel, Belgium, and is among the largest bio‐manufacturing sites in

  5. 77 FR 46112 - Call for Nominations for Advisory Groups, Oregon/Washington

    Science.gov (United States)

    2012-08-02

    ... reference from the stakeholder interest area to be represented; (2) A completed background information...). As required by FACA, council membership must be balanced and representative of the various interests... interest in wild horse management on Steens Mountain. Individuals may nominate themselves or others...

  6. Et dobbelt blik på læring på arbejdspladsen

    DEFF Research Database (Denmark)

    Warring, Niels; Helms Jørgensen, Christian

    2004-01-01

    Arbejdspladsen som læringsmiljø, edited by Vibeke Andersen, Bruno Clematide & Steen Høyrup . Roskilde Universitetsforlag, Copenhagen, pages 179-201. 2004 Kort beskrivelse: Artikel præsenteres en teoretisk og metodisk ramme for at forstå og undersøge læring på arbejdspladsen. Der argumenteres for ...

  7. Centralised versus Decentralised Control Reconfiguration for Collaborating Underwater Robots

    DEFF Research Database (Denmark)

    Furno, Lidia; Nielsen, Mikkel Cornelius; Blanke, Mogens

    2015-01-01

    The present paper introduces an approach to fault-tolerant reconfiguration for collaborating underwater robots. Fault-tolerant reconfiguration is obtained using the virtual actuator approach, Steen (2005). The paper investigates properties of a centralised versus a decentralised implementation an...... an underwater drill needs to be transported and positioned by three collaborating robots as part of an underwater autonomous operation....

  8. Employment Relations in Denmark

    DEFF Research Database (Denmark)

    Madsen, Jørgen Steen; Due, Jesper Jørgen; Andersen, Søren Kaj

    2011-01-01

    Jørgen Steen Madsen, Jesper Due og Søren Kaj Andersen har skrevet et kapitel om udviklingen i dansk arbejdsmarkedsregulering til bogen International and Comparative Employment Relations, redigeret af Greg Bamber, Russell Lansbury og Nick Wailes. Bogen indeholder bidrag, der præsenterer og...

  9. Law and Literature

    DEFF Research Database (Denmark)

    Simonsen, Karen-Margrethe; Tamm, Ditlev

    2017-01-01

    This article presents an introduction to the field of law and literature in Denmark and a legal and literary reading of one of the Western world’s first crime stories, The Pastor of Vejlbye, written by the Danish writer, Steen Steensen Blicher, in 1829. This is a story that is based on a true case...

  10. Self Organized Multi Agent Swarms (SOMAS) for Network Security Control

    Science.gov (United States)

    2009-03-01

    A. Van Veldhuizen . Evolutionary Algorithms for Solving Multi-Objective Problems, chapter MOEA Parallelization. Springer, 2007. 37. Das, Subrata...Mike P. and Willem-Jan van den Heuvel. Service Oriented Architectures: Approaches, Technologies, and Research Issues. Technical report, Tilburg...Tanenbaum, Andrew S. and Maarten Van Steen. Distributed Systems: Principles and Paradigms. Prentice Hall, 2006. 128. Thomas, Tavaris J. Fire Ant: An

  11. Impact of mineral resource depletion

    CSIR Research Space (South Africa)

    Brent, AC

    2006-09-01

    Full Text Available In a letter to the editor, the authors comment on BA Steen's article on "Abiotic Resource Depletion: different perceptions of the problem with mineral deposits" published in the special issue of the International Journal of Life Cycle Assessment...

  12. What Is Old Is New Again: A Systemic Approach to the Challenges of Calculus Instruction

    Science.gov (United States)

    Carreon, Fernando; DeBacker, Stephen; Kessenich, Paul; Kubena, Angela; LaRose, P. Gavin

    2018-01-01

    In the abstract for "Calculus for a New Century: A Pump, Not a Filter," Lynn Steen wrote: "The authors agree on the forces that are reshaping calculus, but disagree on how to respond to these forces. They agree that the current course is not satisfactory, yet disagree about new content emphases. They agree that the neglect of…

  13. Private visit to the CMS assembly site of Dr. Fidel Castro Diaz-Balart from the Superior Institute of Sciences and Nuclear Technologies, Havana, accompanied by His Excellency Mr. Emilio Caballero, Ambassador, Permanent Mission of Cuba in Paris.

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photo 01: Left to right: His Excellency Mr Emilio Caballero; Prof. Tejinder Virdee, Deputy Spokesman of the CMS experiment; Dr Fidel Castro Diaz-Balart; Dr Matthias Schroeder, physicist, Experimental Physics division; Mrs Noëlle Levy, Casa del Habano, Geneva; Dr John Ellis, Adviser for Non-Member State relations; Dr Christian Roche, Senior Advisor to the Director-General. Photo 02: Left to right: His Excellency Mr Emilio Caballero, Prof. Tejinder Virdee, Dr Fidel Castro Diaz-Balart; Dr Matthias Schroeder; Mrs Noëlle Levy, Prof. Juan Antonio Rubio, Head of the Education and Technology Transfer division; Dr John Ellis.

  14. Peeter I residentsid / Jüri Kuuskemaa

    Index Scriptorium Estoniae

    Kuuskemaa, Jüri, 1942-

    2005-01-01

    Peeter I linnaresidents Tolli t. 4 Tallinnas, maja (1662, 1714) ning lossi- ja pargiansambel (1718, arhitekt Niccolo Michetti, 1923. aasta sügisest ehitusel vastutav Mihhail Zemtsov, stukk Antonio Quadri, Salomon Zeltrecht, Matthias Seidtinger, Heinrich von Bergen, laemaal "Diana ja Aktaion" - Ernst Wilhelm Londicer noorem?, laemaaling merepoolses tiibhoones - Johann Heinrich Fick) Kadriorus. Bibliograafia lk. 454

  15. 25 October 2017- Austrian, German and Swiss Science Foundations signing the guest book in the Globe of Science and Innovation

    CERN Multimedia

    Ordan, Julien Marius

    2017-01-01

    Austrian, German and Swiss Science Foundations in Globe: Professor Klement Tockner, Präsident, Fonds zur Förderung der wissenschaftlichen Forschung, Austria; Professor Peter, Strohschneider, Präsident, Deutsche Forschungsgemeinschaft Germany; Professor Matthias Egger, Präsident, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Switzerland

  16. (DEPSCOR FY 09) Obfuscation and Deobfuscation of Intent of Computer Programs

    Science.gov (United States)

    2012-12-21

    increased as the malware distribution mechanism has moved to the web through infected sites. In this use a site is hacked so as to distribute malware to...Simpósio Brasileiro em Segurança da Informaçao e de Sistemas Computacionais (2009). (Chen et al., 2012) Jundong Chen, Matthias R. Brust, Vir V. Phoha

  17. Symposium in honour of Ugo Amaldi's 60th birthday

    CERN Document Server

    Myatt, Gerald; Ellis, Jonathan Richard; Kalmus, George Ernest; Llewellyn Smith, Christopher Hubert; Matthiae, Giorgio; Richter, Burton; Wiik, Bjørn Haavard; Winter, Klaus; CERN. Geneva

    1994-12-07

    Ugo Amaldi,a man of science , G Myattpp total cross section, G Matthiae Neutrino physics, K Winter DELPHI & LEP physics, G Kalmus Supersymmetry, J EllisElectron-proton physics, B WiikLinear colliders, B Richter Closing address, C Llewellyn Smith -

  18. Eesti fenomen Alexanderi tehnika maailmas / Aivi Parijõgi

    Index Scriptorium Estoniae

    Parijõgi, Aivi, 1967-

    2007-01-01

    Alexanderi tehnikast. 2006. aastal EMTA lavakunstikoolis Alexanderi tehnika looja Frederick Matthias Alexander'i sünnipäeva (20.01) puhul toimunud workshopist. Vestlusringis osalevad EMTA Lavakunstikoolis Alexanderi tehnikat õpetav Maret Mursa Tormis, näitleja ja laulja Kärt Tomingas, pedagoog Celia Roose ning Alexanderi tehnika õpetajad mujalt - Dorothea Magonet, Steven Shaw, Masoumeh Atabaki Melrose, Ken Thompson

  19. Pediatric Palliative Care: A Personal Story

    Medline Plus

    Full Text Available ... Duration: 23:09. Matthias 1,036,758 views New 23:09 Language: English Location: United States Restricted ... YouTube Terms Privacy Policy & Safety Send feedback Test new features Loading... Working... Sign in to add this ...

  20. Video Histories, Memories, and Coincidences

    DEFF Research Database (Denmark)

    Kacunko, Slavko

    2012-01-01

    Looping images allows us to notice things that we have never noticed before. Looping a small but exquisite selection of the video tapes of Marcel Odenbach, Dieter Kiessling and Matthias Neuenhofer may allow the discovering of Histories, Coincidences, and Infinitesimal Aesthetics inscribed...

  1. Mari Rahumägi kui särav piksevarras / Katri Soe

    Index Scriptorium Estoniae

    Soe, Katri

    2006-01-01

    Euroopa suurima postimüügi kontserni Karstadt-Quelle Eesti tütarfirma tegevjuhi karjäärist, oma äri alustamisest ja siirdumisest palgatööle. Kommenteerivad Jaanus Rahumägi, Helina Tuuna, Matthias Fink

  2. 77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-11-01

    ... BOUCHARD RAYMOND JOSEPH BOULLE II JEAN-RAYMOND BROMLEY MARGARET ANNE BROWNE CARLA EVELYN BRUCE JAMES TODD... CAMINOS MICHELE CLARE CAMPBELL JESSICA ANNE CHANG WAYNE WEN TIEN CHAN-PALAY VICTORIA LYE-HUA CHEN HOPE MI... RICHARD JOSEPH ARTHUR FUKUDA MEGUMI GAEHWILER YANNIK PETER GEIGER DANIEL CHRISTIAN GEIGER MICHAEL MATTHIAS...

  3. Nový zákon tzv. Svatováclavské bible (1677)

    Czech Academy of Sciences Publication Activity Database

    Koupil, Ondřej

    2013-01-01

    Roč. 5, č. 2 (2013), s. 95-106 ISSN 1804-1132 R&D Projects: GA MK(CZ) DF12P01OVV028 Keywords : Bible in Czech * New Testament 1677 * Georgius Constantius SI * Matthias Steyer SI * Cornelius a Lapide SI Subject RIV: AI - Linguistics

  4. Kinesthetic Ventures Informed by the Work of F. M. Alexander, Stanislavski, Peirce, and Freud.

    Science.gov (United States)

    Bouchard, Ed; Wright, Ben; Protzel, Michael, Ed.

    This book is about education harvested from self-observation. F. Matthias Alexander (1869-1955) studied the experience of self formation, working with motor habits. His method is used in performing arts training to enhance bodily and vocal expression. Like Alexander, Konstantine Stanislavski (1863-1938) and Sigmund Freud (1856-1939) studied human…

  5. Matter-wave bright solitons in effective bichromatic lattice potentials

    Indian Academy of Sciences (India)

    2013-08-01

    Aug 1, 2013 ... M Theis, G Thalhammer, K Winkler, M Hellwig, G Ruff, R Grimm and J H Denschlag, Phys. Rev. Lett. 93, 123001 (2004). [11] Gregor Thalhammer, Matthias Theis, Klaus Winkler, Rudolf Grimm and Johannes Hecker. Denschlag, Phys. Rev. A 71, 033403 (2005). [12] H Sakaguchi and B A Malomed, Phys.

  6. Tänavuse Berlinale filmid süvenevad ihulähedasse / Grete Nootre

    Index Scriptorium Estoniae

    Nootre, Grete

    2006-01-01

    56. Berliini filmifestivali programmidest ja filmidest - USA mängufilm "A Prairie Home Companion" : režissöör Robert Altman, saksa mängufilm "Vaba tahe" ("Der Freie Wille") : režissöör Matthias Glasner, austraalia-inglise "Ettepanek" ("The Proposition") : stsenarist ja helilooja Nick Cave : režissöör John Hillcoat

  7. induced by NF-κB Decoy method

    African Journals Online (AJOL)

    control of immunity. Nature. 1998; 392(6673):245-252. Kabalak G, Dobberstein SB, Matthias T, Reuter S,. 5. The YH, Dorner T, Schmidt RE, Witte T. Association of immunoglobulin-like transcript 6 deficiency with. Sjogren's syndrome. Arthritis Rheum. 2009; 60(10):2923-. 2925. Bonham CA, Peng L, Liang X, Chen Z, Wang L, ...

  8. Formal modeling and verification of systems with self-x properties

    OpenAIRE

    Reif, Wolfgang

    2006-01-01

    Formal modeling and verification of systems with self-x properties / Matthias Güdemann, Frank Ortmeier and Wolfgang Reif. - In: Autonomic and trusted computing : third international conference, ATC 2006, Wuhan, China, September 3-6, 2006 ; proceedings / Laurence T. Yang ... (eds.). - Berlin [u.a.] : Springer, 2006. - S. 38-47. - (Lecture notes in computer science ; 4158)

  9. Igatsedes mägesid

    Index Scriptorium Estoniae

    2008-01-01

    Näitus "Igatsedes mägesid. Šveitsi maastikud Balti kunstis" Kadrioru Kunstimuuseumis. Vaadeldakse Balti kunstnike joonistusreise Šveitsi 18. sajandi teisel poolel ja 19. sajandi alguses. August Matthias Hageni (1794-1878), Carl Grassi (1767-1814), Wilhelm Krause (1757-1728) elust ja loomingust

  10. Establishing the potential dependent equilibrium oxide coverage on platinum in alkaline solution and its influence on the oxygen reduction

    DEFF Research Database (Denmark)

    Wiberg, Gustav; Arenz, Matthias

    2012-01-01

    Publication year: 2012 Source:Journal of Power Sources, Volume 217 Gustav K.H. Wiberg, Matthias Arenz The oxidation process of polycrystalline platinum subjected to alkaline solution is re-examined using a combination of cyclic voltammetry and potential hold techniques in Ar, H2 and O2 purged 0.1...

  11. Lectures on algebraic model theory

    CERN Document Server

    Hart, Bradd

    2001-01-01

    In recent years, model theory has had remarkable success in solving important problems as well as in shedding new light on our understanding of them. The three lectures collected here present recent developments in three such areas: Anand Pillay on differential fields, Patrick Speissegger on o-minimality and Matthias Clasen and Matthew Valeriote on tame congruence theory.

  12. Matouš Konečný a jeho podíl na výchově a vzdělávání bratrských duchovních na počátku 17. století

    Czech Academy of Sciences Publication Activity Database

    Just, Jiří

    -, č. 18 (2016), s. 75-88 ISSN 1802-2502 R&D Projects: GA ČR GA13-08740S Institutional support: RVO:67985955 Keywords : Matouš Konečný * education of clergy * protestant ecclesiastical administration * Matthias Martini * gymnasium illustre in Bremen * peregrinatio academica * protestant schoolbooks * Bohemian Brethren Subject RIV: AB - History

  13. Teekonnad tajutunnelites / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2001-01-01

    Sisu : Siri Hustvedt. Pimesi; Boris Vian. Päevade vaht; Christian Lore Weber. Altarimuusika; Kurt Vonnegut. Kassikangas; Jean Sasson. Printsess Sultana tütred; Karen Robards. Senaatori naine; Matthias Johann Eisen. Näkid, kratid, luupainajad; Mats Traat. Harala elulood; Steven L. McKenzie. Kuningas Taavet; Sally Ward. Terane laps; Ted Hughes. Luuletused

  14. Long-Time Dynamics of Open Quantum Systems

    DEFF Research Database (Denmark)

    Westrich, Matthias

    Matthias Westrich studied the effective evolution of atoms coupled to quantised fields and determined the rate at which atoms relax to their ground state. For positive temperature, he also characterised properties of (quasi-)stationary states for atoms in contact with a heat bath and driven...

  15. Kunstitudengid näitavad Maarjamäe lossi pargis oma vabadussamba tõlgendusi

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Kunstiakadeemia skulptuuritudengid Marit Mardla, Matthias-Jakob Sildnik, Mikk Madisson, Liis Dvorjanski, Uku Sepisvart, Hannes Aasamets, Kadri Allekand, Kristin Orav, Loore Raav, Jekaterina Kultajeva, Li Yang, Kristel Aasjõe, Liivi Tantaal, Jass Kaselaan, Edith Karlson, Kadri Metstak, Berit Talpsepp ja Eike Eplik näitavad oma töid näitusel "Vabaduse monumendid"

  16. More and more together : Legal family formats for same-sex and different-sex couples in European countries – Comparative analysis of data in the LawsAndFamilies Database

    NARCIS (Netherlands)

    Waaldijk, C.

    2017-01-01

    This report (edited by Kees Waaldijk) includes contributions by Daniel Damonzé, Marie Digoix, Marina Franchi, Natalie Nikolina, José Ignacio Pichardo Galán, Giulia Selmi, Matias de Stéfano Barbero, Matthias Thibeaud, Jose A.M. Vela, Kees Waaldijk, and Giuseppe Zago. This report offers a

  17. RMIT at the TREC 2015 LiveQA Track

    Science.gov (United States)

    2015-11-20

    recipient of an Australian Research Council DECRA Research Fellowship (DE140100275). REFERENCES [1] Michael Collins. Head-driven statistical models for...18th Australasian Document Computing Symposium, pages 58–65. ACM, 2013. [4] Matthias Petri, Alistair Moffat, and J Shane Culpepper. Score-safe term

  18. List of Registered Participants

    Indian Academy of Sciences (India)

    user1

    Heald, George. ASTRON heald@astron.nl. Hoeft, Matthias. Thueringer Landessternwarte Tautenburg hoeft@tls-tautenburg.de. Ishwara Chandra, C. H.. NCRA-TIFR ishwar@ncra.tifr.res.in. Johnston-Hollitt, Melanie. School of Chemical & Physical Sciences. Melanie.Johnston-Hollitt@vuw.ac.nz. Jacob, Joe. Newman College.

  19. mica – music information center austria

    OpenAIRE

    2010-01-01

    1994 wurde das österreichische Musikinformationszentrum (mica) im Auftrag des österreichischen Bundesministers für Unterricht und Kunst (Rudolf Scholten) von den Bundeskuratoren für Musik (L. Knessl, Christian Scheib) gegründet (Geschäftsführer 1994–99 Matthias Finkentey, 1999–09 Peter Rantasa, ab 2009 Sabine Reiter).

  20. Kindla peale minek / Küllo Arjakas

    Index Scriptorium Estoniae

    Arjakas, Küllo, 1959-

    2007-01-01

    Rets. rmt.: Eberle, Henrik ; Ulm, Matthias. Hitleri toimik : NKVD salajane ettekanne Jossif Stalinile, koostatud Hitleri isikliku adjutandi Otto Günsche ja kammerteener Heinz Linge ülekuulamise protokollide põhjal Moskvas 1948/49. [Tallinn] : Tammerraamat, 2006 ; Bassett, Richard. Canaris : Hitleri luureülem : Wilhelm Canarise mõistatus : [1887-1945]. Tallinn : Varrak, 2006

  1. Poliitiliselt korrektselt on raske sündimust suurendada / Villu Zirnask

    Index Scriptorium Estoniae

    Zirnask, Villu, 1966-

    2008-01-01

    Autor käsitleb majandusteadlaste Vincenzo Galasso, Roberta Gatti ja Paola Profeta ning Matthias Doepke, Moshe Hazani ja Yishay D. Maozi sündimusteemalist uuringut ning järeldab, et praegustes tingimustes on võimatu samasugust beebibuumi esile kutsuda, kui oli 1950. aastatel. Diagramm: Sündimuse määra trend Eestis, Soomes ja Saksamaal 1950-2005

  2. Current Evaluation Procedures for Fertilizers and Soil Conditioners Used in Organic Agriculture. Proceedings of a workshop held April 29–30, 2004 at Emerson College, Great Britain

    OpenAIRE

    Canali, Stefano; Stopes, Christopher; Schmid, Otto; Speiser, Bernhard

    2005-01-01

    Table of Contents Fertilizers and soil conditioners in organic farming in Austria Alexandra Hozzank and Wilfried Hartl Fertilizers and soil conditioners in organic farming in the Czech Republic Anamarija Slabe Fertilizers and soil conditioners in organic farming in Denmark Rasmus Ørnberg Eriksen and Erik Steen Kristensen Fertilizers and soil conditioners in organic farming in France Marie-Christine Monnier Fertilizers and soil conditioners in organic fa...

  3. New geologic evidence for additional 16.5-15.5 Ma silicic calderas in northwest Nevada related to initial impingement of the Yellowstone hot spot

    International Nuclear Information System (INIS)

    Coble, Matthew A; Mahood, Gail A

    2008-01-01

    Three silicic calderas have been newly identified in northwest Nevada west of McDermitt caldera. This volcanism is interpreted to have formed during a short interval at 16.5-15.5 Ma, during the waning stage of Steens flood basalt volcanism after the initial impingement of the Yellowstone hot spot. New mapping demonstrates that the area affected by this mid-Miocene silicic volcanism is significantly larger than previously appreciated in the western U.S.

  4. New geologic evidence for additional 16.5-15.5 Ma silicic calderas in northwest Nevada related to initial impingement of the Yellowstone hot spot

    Energy Technology Data Exchange (ETDEWEB)

    Coble, Matthew A; Mahood, Gail A [Department Geological and Environmental Sciences, 450 Serra Mall, Bldg 320, Stanford University, Stanford, CA 94305-3115 (United States)

    2008-10-01

    Three silicic calderas have been newly identified in northwest Nevada west of McDermitt caldera. This volcanism is interpreted to have formed during a short interval at 16.5-15.5 Ma, during the waning stage of Steens flood basalt volcanism after the initial impingement of the Yellowstone hot spot. New mapping demonstrates that the area affected by this mid-Miocene silicic volcanism is significantly larger than previously appreciated in the western U.S.

  5. Y. Laberge on Raphael-Hernadez and Steen’s AfroAsian encounters: Culture, History, Politics.

    Directory of Open Access Journals (Sweden)

    2008-12-01

    Full Text Available Heike Raphael-Hernadez and Shannon Steen,  Eds. AfroAsian encounters: Culture, History, Politics. New York: New York University Press, 2006.  xxiii + 342 p. An overlooked, interdisciplinary, often innovative book, Afroasian encounters: Culture, History, Politics offers a collection of seventeen new essays related to the African-Asian intersections, cosmopolitanism and cross-cultural theories. In terms of emerging disciplines, we already had Atlantic studies (or "Trans-Atlantic studies", an i...

  6. Transitional geomagnetic impulse hypothesis: Geomagnetic fact or rock-magnetic artifact?

    Science.gov (United States)

    Camps, Pierre; Coe, Robert S.; PréVot, Michel

    1999-08-01

    A striking feature of the Steens Mountain (Oregon) geomagnetic polarity reversal is the two (maybe three) extremely rapid field directional changes (6 degrees per day) proposed to account for unusual behavior in direction of remanent magnetization in a single lava flow. Each of these very fast field changes, or impulses, is associated with a large directional gap (some 90°) in the record. In order to check the spatial reproducibility of the paleomagnetic signal over distances up to several kilometers, we have carried out a paleomagnetic investigation of two new sections (B and F) in the Steens summit region which cover the second and the third directional gap. The main result is the description of two new directions, which are located between the pre second and post second impulse directions. These findings weigh against the hypothesis that the geomagnetic field cause the unusual intraflow fluctuations, which now appears to be more ad hoc as an explanation of the paleomagnetic data. However, the alternative baking hypothesis remains also ad hoc since we have to assume variable rock magnetic properties that we have not yet been able to detect within the flows at the original section Steens A and D 1.5 km to the north. In addition, new results for 22 transitional and normal lava flows in section B are presented that correlate well with earlier results from section A.

  7. Determining the Ages and Eruption Rates of the Columbia River Basalt Group Magnetozones

    Science.gov (United States)

    Jarboe, N. A.; Coe, R. S.; Renne, P. R.; Glen, J. M.

    2009-12-01

    The Columbia River Basalt Group (CRBG) eruptions have a well defined relative magnetostratigraphy but have not been definitively correlated to the geomagnetic polarity time scale. Fifteen 40Ar/39Ar ages from lavas erupted in the R0 through R1 magnetozones of the CRBG, in conjunction with the geomagnetic polarity time scales (GPTS) of Lourens et al. (2004) and Billups et al. (2004) based on sea-floor spreading rates and orbital tuning, identify the R0 as the C5Cr chron. Particularly important for correlation to GPTS are four ages from transitionally magnetized lavas from the R0-N0 transition (Steens Reversal) found at Steens Mountain, Catlow Peak and Poker Jim Ridge. These transitionally magnetized lavas, found in sections separated by ~100 km and definitively erupted during the same reversal based on the similarity of their transitional field paths, have a weighted mean age 16.58 ±± 0.19 Ma (±± stands for two sigma). At the top of the Catlow Peak section, a more precise age of 16.654 ±± 0.050 Ma of the normally magnetized Oregon Canyon Tuff places further constraints on the age of the Steens Reversal. Using Isoplot’s Bayesian statistical “Stacked Beds” function on four flows at Catlow Peak (including the mean age of the Steens Reversal) gives a best age of the Steens Reversal at that section of 16.73 +0.13/-0.08 Ma (95% confidence). A normally magnetized Imnaha Basalt age of 16.85 ±± 0.42 Ma, a normally magnetized basalt age from Pole Creek (16.45 ±± 0.22 Ma), and other ages correlate the N0 to the C5Cn.3n chron. Depending on the geomagnetic polarity time scale model, the eruption rate from N0 through R2 (0.34-0.42 Ma in the middle and the bulk of the CRBG emplacement) averaged 0.33-0.45 km3/a and peaked at a rate 1 ½ to 4 ½ times higher during R2. Billups, K., H. Palike, J. E. T. Channell, J. C. Zachos, and N. J. Shackleton, Astronomic Calibration of the Late Oligocene Through Early Miocene Geomagnetic Polarity Time Scale, Earth and Planetary

  8. Kaunis ja õudne : Raamaturida / Arno Oja

    Index Scriptorium Estoniae

    Oja, Arno, 1950-

    1995-01-01

    Beer, Natalie. Meister Mathis : Matthias Grünewaldi romaan; Pezold, Leopold. Kolme Eestimaa kunstniku rännuaastad; Vint, Maara. Vint, Eve-Maria. Võlulehvik; Seton, Anya. Katherine, 2.osa; Suosalmi, Kerttu-Kaarina. Õnnekütt; Herriott, James. Koerajutud; Laos, Ester. Õhtuks koju; Ewers, Hanns Heinz. Alraune; King, Stephen. Raamatukogupolitseinik; Pabut, Talvo. Surma suflöör; Loon, Paul van. Õuduste käsiraamat

  9. Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy

    OpenAIRE

    Unterweger, Harald; Subatzus, Daniel; Tietze, Rainer; Janko, Christina; Poettler, Marina; Stiegelschmitt, Alfons; Schuster, Matthias; Maake, Caroline; Boccaccini, Aldo R; Alexiou, Christoph

    2015-01-01

    Harald Unterweger,1 Daniel Subatzus,1 Rainer Tietze,1 Christina Janko,1 Marina Poettler,1 Alfons Stiegelschmitt,2 Matthias Schuster,3 Caroline Maake,4 Aldo R Boccaccini,5 Christoph Alexiou11ENT Department, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung Professorship, University Hospital Erlangen; 2Institute of Glass and Ceramics, Department of Materials Science and Engineering, University Erlangen-Nuremberg, 3Materials for Electronics and Ene...

  10. Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

    CSIR Research Space (South Africa)

    Zimmermann, S

    2014-03-01

    Full Text Available Stefanie Zimmermann 1,2, Gerda Fouché 3, Maria De Mieri 1, Yukiko Yoshimoto 4, Toyonobu Usuki 4, Rudzani Nthambeleni 3, Christopher J. Parkinson 5, Christiaan van der Westhuyzen 3, Marcel Kaiser 2,6, Matthias Hamburger 1 and Michael Adams 1,* 1... 1. Introduction Sleeping sickness, or human African trypanosomiasis (HAT), is a deadly protozoal disease caused by Trypanosoma brucei species spread by tsetse flies (Glossina spp.). The two human pathogenic subspecies, T. b. rhodesiense (95...

  11. Berliinis poole peal / Endel Link

    Index Scriptorium Estoniae

    Link, Endel

    2006-01-01

    56. Berliini filmifestivalist ja filmidest - USA mängufilm "A Prairie Home Companion" : režissöör Robert Altman, saksa mängufilmid "Vaba tahe" ("Der Freie Wille") : režissöör Matthias Glasner ja "Elementaarosakesed" ("Elementarteilchen") : režissöör Oskar Roehler, inglise-kanada mängufilm "Lumekeeks" ("Snowcake") : režissöör Marc Evans

  12. Advances in network complexity

    CERN Document Server

    Dehmer, Matthias; Emmert-Streib, Frank

    2013-01-01

    A well-balanced overview of mathematical approaches to describe complex systems, ranging from chemical reactions to gene regulation networks, from ecological systems to examples from social sciences. Matthias Dehmer and Abbe Mowshowitz, a well-known pioneer in the field, co-edit this volume and are careful to include not only classical but also non-classical approaches so as to ensure topicality. Overall, a valuable addition to the literature and a must-have for anyone dealing with complex systems.

  13. Svoboda na Maarjamjagi

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Kunstiakadeemia skulptuuritudengite workshopil loodud vabaduse monumentide näitus Eesti Ajaloomuuseumi pargis Maarjamäel. Projekt أVabaduse monumendidؤ on osa Eesti Ajaloomuuseumi näitusest أIseolemise tahe. 90 aastat Eesti Vabariikiؤ Maarjamäe lossis. Oma töid eksponeerivad skulptuuritudengid Marit Mardla, Matthias-Jakob Sildnik, Liis Dvorjanski, Jekaterina Kultajeva, Li Yang ja teised

  14. BRAIN JOURNAL - PREFACE (OF THE FIRST SPECIAL ISSUE)

    OpenAIRE

    Bogdan Patrut

    2010-01-01

    BRAIN. Broad Research in Artificial Intelligence and Neuroscience, ISSN 2067-3957, Volume 1, July 2010, Special Issue on Complexity in Sciences and Artificial Intelligence Editors • Barna Iantovics, Petru Maior University, Targu Mures, Romania • Dumitru Rădoiu, Petru Maior University, Targu Mures, Romania • Marius Măruşteri, Universiy of Medicine and Pharmacy, Targu Mures, Romania • Matthias Dehmer, Institute for Bioinformatics and Translational Research, The Health and Life Scien...

  15. Föderaalne Keskkonnaagentuur Dessaus

    Index Scriptorium Estoniae

    2008-01-01

    Büroohoone Dessau endisel tööstusalal. Linnaehituslikust lahendusest ja ökoloogilistest nõuetest hoonele. Loetletud hoone säästlikkuse põhipunktid. Projekteerija: Sauerbruch Hutton (Berliin). Autorid: Matthias Sauerbruch, Louisa Hutton, Juan Lucas Young, Jens Ludloff. Konstruktor: Krebs & Kiefer (Berliin). Energeetika ja keskkonnatehnika: Zibell Willner & Partner (Köln/Berliin). Projekt: 2001, valmis: 2005. Asendiplaan, 2 värv. välisvaadet, sisevaade

  16. Equations of discontinuity

    International Nuclear Information System (INIS)

    Wengenmayr, R.

    2008-01-01

    Max Planck founded quantum physics in 1900 - accidentally. In the years following 1920, many physicists developed modern quantum mechanics - through labyrinthine paths and amid intense disputes. This complex history is being studied by a group of historians working with JUeRGEN RENN, Director at the MAX PLANCK INSTITUTE FOR THE HISTORY OF SCIENCE, his colleague Christoph Lehner, and a group of physicists working with MATTHIAS SCHEFFLER, Director at the FRITZ HABER INSTITUTE. (orig.)

  17. Umfrageforschung: Entscheidungsgrundlage für Politik und Wissenschaft

    OpenAIRE

    2011-01-01

    "Der vorliegende Tagungsband dokumentiert die Beiträge der wissenschaftlichen Tagung 'Umfrageforschung - Entscheidungsgrundlage für Politik und Wissenschaft', die am 30. Juni und 1. Juli 2011 gemeinsam vom Statistischen Bundesamt, dem ADM Arbeitskreis Deutscher Markt- und Sozialforschungsinstitute e.V. und der Arbeitsgemeinschaft Sozialwissenschaftlicher Institute e.V. (ASI) in Wiesbaden durchgeführt wurde." (Autorenreferat). Inhaltsverzeichnis: Christian König, Matthias Stahl, Erich Wiegand:...

  18. Vremja Dostojevskogo / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2007-01-01

    Dostojevski kangelased Eesti teatrilaval: "Onu unenägu" Vene Teatris (lavastaja Mihhail Tshumatshenko), Matthias Andersoni "Kuritöö, kodutööd, karistus, raha, pensionäri tapmine" Teises Teatris (lavastajad Erki Aule ja Artjom Garejev), Eesti - Läti - Leedu vene teatrite koostööprojekt "Vene naer" (lavastaja Roman Kozak), "Sortsid" Eesti Draamateatris (lavastaja Hendrik Toompere jun.), "Krokodill" Vana Baskini Teatris (lavastaja Mark Rozovski)

  19. Dostojevski aeg / Boris Tuch ; tõlk. Madis Kolk

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2007-01-01

    Dostojevski kangelased Eesti teatrilaval: "Onu unenägu" Vene Teatris (lavastaja Mihhail Tshumatshenko), Matthias Andersoni "Kuritöö, kodutööd, karistus, raha, pensionäri tapmine" Drugoi Teatr (lavastajad Erki Aule ja Artjom Garejev), Eesti - Läti - Leedu vene teatrite koostööprojekt "Russki smehh" (lavastaja Roman Kozak), "Sortsid" Eesti Draamateatris (lavastaja Hendrik Toompere jun.), "Krokodill" Vana Baskini Teatris (lavastaja Mark Rozovski)

  20. Three essays on corruption and auctions

    OpenAIRE

    PAPIOTI, Katerina Chara

    2014-01-01

    Defence date: 1 December 2014 Examining Board: Professor Massimo Morelli, Bocconi University, Supervisor; Professor Andrea Mattozzi, EUI; Professor Marco Celentani, Universidad Carlos III; Professor Matthias Dahm, University of Nottingham. This thesis contributes to the understanding of corruption and auctions. It consists of three chapters focusing on diverse aspects of these two general topics as well as their combinations, from an applied microeconomic theory perspective: (i) the eff...

  1. Appropriering, system, bogobjekt

    DEFF Research Database (Denmark)

    Kromann, Thomas Hvid

    og en afpersonaliseringens poetik bliver konstrueret og typologiseret ud fra et heterogent og spredt tekstmateriale. En poetik, der er kendetegnet af en vidtdreven afmytologisering og afpersonalisering af kunstnerrollen og værket. I kapitel 2, Appropriering, analyseres approprieringsteknikker som...... værker af Bjørn Nørgaard, Hans-Jørgen Nielsen, Henning Christiansen, Vagn Steen og Per Kirkeby (i kap. 2, 3 og 4) analyseres eksempler på appropriering, systemer og bogobjekter. Afpersonalisering er som strategi ikke en homogen metode, men derimod en heterogen og individuel praksis, der spænder fra...

  2. Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death.

    Science.gov (United States)

    Stone, Matthew L; Zhao, Yunge; Robert Smith, J; Weiss, Mark L; Kron, Irving L; Laubach, Victor E; Sharma, Ashish K

    2017-12-21

    Lung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant patients. This study investigates the anti-inflammatory and immunomodulatory role of human mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) to attenuate lung IR injury and improve of ex-vivo lung perfusion (EVLP)-mediated rehabilitation in donation after circulatory death (DCD) lungs. C57BL/6 wild-type (WT) mice underwent sham surgery or lung IR using an in vivo hilar-ligation model with or without MSCs or EVs. In vitro studies used primary iNKT cells and macrophages (MH-S cells) were exposed to hypoxia/reoxygenation with/without co-cultures with MSCs or EVs. Also, separate groups of WT mice underwent euthanasia and 1 h of warm ischemia and stored at 4 °C for 1 h followed by 1 h of normothermic EVLP using Steen solution or Steen solution containing MSCs or EVs. Lungs from MSCs or EV-treated mice had significant attenuation of lung dysfunction and injury (decreased edema, neutrophil infiltration and myeloperoxidase levels) compared to IR alone. A significant decrease in proinflammatory cytokines (IL-17, TNF-α, CXCL1 and HMGB1) and upregulation of keratinocyte growth factor, prostaglandin E2 and IL-10 occurred in the BAL fluid from MSC or EV-treated mice after IR compared to IR alone. Furthermore, MSCs or EVs significantly downregulated iNKT cell-produced IL-17 and macrophage-produced HMGB1 and TNF-α after hypoxia/reoxygenation. Finally, EVLP of DCD lungs with Steen solution including MSCs or EVs provided significantly enhanced protection versus Steen solution alone. Co-cultures of MSCs or EVs with lung endothelial cells prevents neutrophil transendothelial migration after exposure to hypoxia/reoxygenation and TNF-α/HMGB1 cytomix. These results suggest that MSC-derived EVs can attenuate lung inflammation and injury after IR as well as enhance EVLP-mediated reconditioning of

  3. Index to FAA Office of Aviation Medicine Reports: 1961 through 1998.

    Science.gov (United States)

    1999-01-01

    marihuana . AD775889 73-13 Tobias, J. V., and Irons, F. M: Reception of distorted speech. AD777564 73-14 Thackray, R. I., Jones, K. N., and...involved in midair collisions. ADAO16277 75-6 Lewis, M. F., Ferraro, D. P., Mertens, H. W., and Steen, J. A: Interaction between marihuana and...71-17. ... human tolerance, 62-6. ... marihuana effects on performance, 75-6. ... oxygen masks, efficiency of, 62-21, 66-7, 66-9, 66-20, 67-3, 67

  4. Beyond Nation-Based Frameworks

    DEFF Research Database (Denmark)

    Ørum, Tania

    2012-01-01

    in Copenhagen, thanks to the German artist and galerist Arthur Köpcke living there who had relations to the Nouveau Réalisme group in Paris. Ikegami suggests that Moderna Museet looses its central position and relapses into a provincial status when the link to New York is lost, thus highlighting the unequal...... Steen, was inspired by Swedish artists and art historians connected to Moderna Museet. Other more temporary or permanent Nordic institutions were for instance the summer schools at Hindsgavl Slot, various little magazines and small presses, and Biskops Arnö where generations of young poets from...

  5. Beware the beast in black

    DEFF Research Database (Denmark)

    Jensen, Kim Ebensgaard

    2015-01-01

    Acknowledging the need for contemporary philology to expand beyond the literary canon, this article presents a stylistic analysis of Judas Priest's 'Night Crawler' within the framework of cognitive poetics (e.g. Stockwell 2002; Steen/Gavins 2003; Burke 2005; Brandt 2008; Vandaele/Brône 2009...... of quantity (Grice 1975) in referring to the monstrous antagonist in the narrative told in the song. In keeping with the purpose of cognitive poetics, the analysis also proposes a number of cognitive capacities that the reader is likely to draw on when construing the vague descriptions of the monster...

  6. Beware the beast in black

    DEFF Research Database (Denmark)

    Jensen, Kim Ebensgaard

    2015-01-01

    Acknowledging the need for contemporary philology to expand beyond the literary canon, this article presents a stylistic analysis of Judas Priest's 'Night Crawler' within the framework of cognitive poetics (e.g. Stockwell 2002; Steen/Gavins 2003; Burke 2005; Brandt 2008; Vandaele/Brône 2009...... of quantity (Grice 1975) in referring to the monstrous antagonist in the narrative told in the song. In keeping with the purpose of cognitive poetics, the analysis also proposes a number of cognitive capacities that the reader is likely to draw on when construing the vague descriptions of the monster...

  7. Complex Strategic Choices

    DEFF Research Database (Denmark)

    Leleur, Steen

    to strategic decision making, Complex Strategic Choices presents a methodology which is further illustrated by a number of case studies and example applications. Dr. Techn. Steen Leleur has adapted previously established research based on feedback and input from various conferences, journals and students...... resulting in new material stemming from and focusing on practical application of a systemic approach. The outcome is a coherent and flexible approach named systemic planning. The inclusion of both the theoretical and practical aspects of systemic planning makes this book a key resource for researchers...

  8. Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared to clopidogrel: Data from the PLATO trials

    DEFF Research Database (Denmark)

    Patel, Manesh R.; Becker, Richard C.; Wojdyla, Daniel M.

    Abstract 14299: Cardiovascular Events in Acute Coronary Syndrome Patients With Peripheral Arterial Disease Treated With Ticagrelor Compared to Clopidogrel: Data From the PLATO Trial Manesh R Patel1; Richard C Becker1; Daniel M Wojdyla2; Håkan Emanuelsson3; William Hiatt4; Jay Horrow5; Steen Husted6...... Uppsala, Sweden 10 Cardiology, Uppsala Clinical Rsch center, 75185 Uppsala, Sweden Background: Patients with peripheral artery disease (PAD) and acute coronary syndrome (ACS) are at high risk for clinical events and are often difficult to manage. We evaluated cardiovascular outcomes of ACS patients...

  9. The seismic expression and hydrocarbon potential of subsurface impact craters

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, R.; Westbroek, H.H.; Lawton, D. [Calgary Univ., AB (Canada). Dept. of Geology and Geophysics

    1995-12-31

    The seismic characteristics of meteorite impact craters and their potential as oil and gas reservoirs were discussed. Seismic data from James River, Alberta, in the Western Canada Sedimentary Basin show subsurface anomalies to be meteorite impact structures. The White Valley structure in Saskatchewan has similar features and seismic anomalies indicate that it too could be a meteorite impact structure, although other possibilities have been proposed. Other impact structures in western Canada such as the Steen River structure and the Viewfield crater have or are producing hydrocarbons. 5 refs., 2 figs.

  10. Europe of energy and transports

    International Nuclear Information System (INIS)

    Ruete, M.

    2006-01-01

    The Directorate-General for Energy and Transport (DG TREN), based in Brussels, reports to Jacques Barrot, Vice-President of the European Commission, Commissioner for Transport and Andris Piebalgs, Commissioner for Energy. The Directorate-General for Energy and Transport is headed by Matthias Ruete and has a staff of over 1000 people in ten Directorates located in Brussels and Luxembourg. In addition to the development of Community transport and energy policies, including dealing with State aid, the Directorate-General is responsible for managing the financial support programmes for the trans-European networks, technological development and innovation. In this paper, M. Ruete tells us more about these missions

  11. The Effect of Caffeine on Human Dark Adaptation.

    Science.gov (United States)

    1977-04-06

    UO~ mg. 100 mg .< Placebo T.M. 13** 9 3** G..11 (2 te)10 S.H. 9 (1 tie) 4 13** P < .05 **p. .005 N =13 K 9 EXPERIMENT II The analysis of Experiment...caffeinated session were not included in the analysis . A double blind design was again employed. Each S received a schedule in accordance wihh which he... tannins , and sodium in coffee, tea and cocoa. Journal of the American Medical Association, 1955, 158, 1030-1031. 17. Matthias, H., 8 Erdmann, D. The

  12. Bibliografía

    OpenAIRE

    2015-01-01

    Abram, Matthias1992. Lengua, cultura e identidad. El proyecto EBl 1985-1990. Quito: Proyecto EBI/Abya Yala. Academia Mayor de la Lengua Quechua1995 Diccionario Quechua-Español-Quechua. Qheswa-Español-Qheswa Simi Taqe. Cuzco: Municipalidad del Cuzco. Adelaar, Willem1977. Tarma Quechua. Grammar, Texts, Dictionary. Lisse: Peter de Ridder Press.1986 “La relación quechua-aru: perspectivas para la separación del léxico”. Revista Andina 4 (2): 379426.1999. “Unprotected Languages: The Silent Death of...

  13. Section 5: Adapting Requirements Practices in Different Domains

    Science.gov (United States)

    Robinson, William

    Technology has a tremendous impact on society. In recent years, the Internet, World Wide Web, and Web 2.0 has changed the nature of commerce, government, and of course software development. It affects the practices of producing requirements and as well as the kinds of systems to be designed. The effect of converging technologies on the role of requirements engineering is considered in the first article by Matthias Jarke, while the effect of technology on requirements practices is considered in the second article by Walt Scacchi. Together, they provide theoretical and practical perspective on requirements engineering issues faced in a modern, technology driven world.

  14. Superconductivity and magnetism: From antagonism to mutual interplay

    International Nuclear Information System (INIS)

    Steglich, Frank

    2007-01-01

    In this paper, a brief survey is given on a number of research activities devoted to exploring the relationship between superconductivity and magnetism in f-electron systems. The starting point for these activities has been the pioneering work of 1958 by Matthias and coworkers illustrating the antagonistic nature of the two phenomena. Subsequent efforts concerned the investigation of Kondo superconductors and Kondo-lattice systems (in the 1970s), heavy-fermion metals (in the 1980s and 90s) and quantum critical materials (in the last decade). The latter systems are especially interesting as they promise a deeper insight into the mutual interplay between unconventional superconductivity and magnetism

  15. The Pajarito Plateau: A bibliography

    Science.gov (United States)

    Mathien, Frances Joan; Steen, Charlie R.; Allen, Craig D.

    1993-01-01

    This bibliography is the result of two initially independent projects. As the consulting archaeologist at Los Alamos National Laboratory (LANL), Charlie R. Steen collected entries at the suggestion of the staff of the Environmental Surveillance Group of the Health, Safety, and Environmental Division, HSE-8. The primary purpose was to aid the staff in evaluating cultural resources on LANL lands. In addition to works that related to the archaeology and history of the area, Steen included notations of a few books and articles in other fields such as geology and natural history. It was hoped that they also would be of value to other organizations and to students of past human activities on the Pajarito Plateau.At the same time, the National Park Service (NPS) was planning a major survey of Bandelier National Monument (BNM). As part of this plan, the author was asked to prepare a background document that described research previously carried out in the area, including an annotated bibliography. Although the survey would be limited to the park boundaries, the larger Pajarito Plateau is a more logical study area from physiographic, environmental, and cultural perspectives; hence the focus was on this larger region. Mathien (1986) also included some references to natural resources studies, particularly those initiated by NPS within Bandelier National Monument.Both bibliographies were made available to Colleen Olinger and Beverly Larson of the Health and Environmental Services Group at Los Alamos. They realized that while neither was complete, each included entries missing from the other. Larson suggested the two bibliographies be combined. (At this time, Craig Allen was studying the landscape of the Jemez Mountains [Allen 1984c, 1989]. His investigations included much detailed information on natural resource studies and were added in 1991 and 1992.)To limit the scope of their work, Steen and Mathien had chosen their parameter: the Pajarito Plateau. Geographically, the

  16. Environmental law. 2. rev. and enl. ed.; Umweltrecht

    Energy Technology Data Exchange (ETDEWEB)

    Koch, H.J. (ed.) [Hamburg Univ. (Germany). Forschungsstelle Umweltrecht

    2007-07-01

    The text book under consideration already is addressed to lawyers and students of jurisprudence. It enables an introduction into the general environmental law and consists of sixteen autonomous chapters: (a) International law in the field of ecology (Matthias Buck, Roda Verheyen); (b) European and national environmental constitutional law (Johannes Caspar); (c) General environmental administrative law (Ulrich Ramsauer); (d) Pollution abatement law (Hans-Joachim Koch); (e) Water protection law (Silke Laskowski, Cornelia Ziehm); (f) Recycling economy law and waste management law (Martin Dieckmann, Moritz Reese); (g) Nature conservation law (Christian Maass, Peter Schuette); (h) Soil conservation law and contaminated sites law (Nikolaus Herrmann); (i) Energy legal regulations as an instrument of environmental protection (Wolfgang Ewer); (j) Atomic energy law (Klaus Jankowski); (k) Genetic engineering law (Ursula Prall); (l) Law of hazardous materials (Eckhard Pache); (m) Environmental law in planning law (Nikolaus Hermann); (n) Environment and traffic (Philipp Hermann, Ekkehard Hofmann); (o) Agriculture and ecology (Ulf-Henning Moeker); (p) Liberal trade and environmental protection (Matthias Buck).

  17. The future of bioenergy; Die Zukunft der Bioenergie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    This volume contains the following five contributions: 1. The impact of the governmental biogas production on agricultural rents in Germany. An econometric study (Hendrik Garvert); 2. Biogas as price drivers on the land and rental market? An Empirical Analysis (Uwe Latacz-Lohmann); 3. Analysis of comparative advantage of bioenergy in electricity and heat production. Greenhouse gas abatement and mitigation costs in Brandenburg (Lukas Scholz); 4. Flexibility potential of biogas and biomethane CHP in the investment portfolio (Matthias Edel); 5. Legal possibilities and limitations of a reform of the system for the promotion of bioenergy (Jose Martinez). [German] Dieser Band enthaelt folgende fuenf Themenbeitraege: 1. Die Auswirkungen der staatlichen Biogasfoerderung auf landwirtschaftliche Pachtpreise in Deutschland. Eine oekonometrische Untersuchung (Hendrik Garvert); 2. Biogas als Preistreiber am Bodenmarkt und Pachtmarkt? Eine empirische Analyse (Uwe Latacz-Lohmann); 3. Analyse komparativer Kostenvorteile von Bioenergielinien in der Strom- und Waermeproduktion Treibhausgasvermeidung und Vermeidungskosten in Brandenburg (Lukas Scholz); 4. Flexibilisierungspotenzial von Biogas- und Biomethan-BHKWs im Anlagenbestand (Matthias Edel); 5. Rechtliche Moeglichkeiten und Grenzen einer Reform des Systems zur Foerderung der Bioenergie (Jose Martinez).

  18. Conference scene: DGVS spring conference 2009.

    Science.gov (United States)

    Kolligs, Frank Thomas

    2009-10-01

    The 3rd annual DGVS Spring Conference of the German Society for Gastroenterology (Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten) was held at the Seminaris Campus Hotel in Berlin, Germany, on 8-9 May, 2009. The conference was organized by Roland Schmid and Matthias Ebert from the Technical University of Munich, Germany. The central theme of the meeting was 'translational gastrointestinal oncology: towards personalized medicine and individualized therapy'. The conference covered talks on markers for diagnosis, screening and surveillance of colorectal cancer, targets for molecular therapy, response prediction in clinical oncology, development and integration of molecular imaging in gastrointestinal oncology and translational research in clinical trial design. Owing to the broad array of topics and limitations of space, this article will focus on biomarkers, response prediction and the integration of biomarkers into clinical trials. Presentations mentioned in this summary were given by Matthias Ebert (Technical University of Munich, Germany), Esmeralda Heiden (Epigenomics, Berlin, Germany), Frank Kolligs (University of Munich, Germany), Florian Lordick (University of Heidelberg, Germany), Hans Jorgen Nielsen (University of Copenhagen, Denmark), Anke Reinacher-Schick (University of Bochum, Germany), Christoph Röcken (University of Berlin, Germany), Wolff Schmiegel (University of Bochum, Germany) and Thomas Seufferlein (University of Halle, Germany).

  19. Cell-baswd non-invasive prenatal testing

    DEFF Research Database (Denmark)

    Uldbjerg, Niels; Singh, Ripudaman; Christensen, Rikke

    that fetal cells are stable in blood samples stored up to 48 hours. Using these cells, we have detected subchromosomal abnormalities including one with mosaic 45, X/46, X, r(X) which have been confirmed at DNA from chorion villus sampling. Conclusions: We conclude that fcmb-NIPT deserves full attention......CONTROL ID: 2520273 ABSTRACT FINAL ID: OC06.03 TITLE: Cell based Non-invasive Prenatal Testing (NIPT) AUTHORS (FIRST NAME, LAST NAME): Niels Uldbjerg2, Ripudaman Singh4, Rikke Christensen3, Palle Schelde4, Ida Vogel1, Else Marie Vestergaard3, Lotte Hatt4, Steen Kølvrå4 INSTITUTIONS (ALL): 1...... therefore hypothesize that NIPT based on amplified DNA from fetal cells circulating in maternal blood (fcmb-NIPT) will make it possible to detect subchromosomal aberrations. Methods: We obtained 30 ml of whole blood from 100 pregnant women undergoing chorion villus sampling at a gestational age of 10...

  20. Engineering of Saccharomyces cerevisiae for production of resveratrol and its derivatives

    DEFF Research Database (Denmark)

    Li, Mingji

    were published in Applied and Environmental Microbiology (Jendresen et al., 2015). I then constructed the TAL pathway to resveratrol by expressing the two TAL genes in combination with 4-coumaryl-CoA ligase (4CL) from Arabidopsis thaliana and resveratrol synthase (VST) from Vitis vinifera in S...... carbon sources. I adopted rational metabolic engineering rational design strategies, synthetic biology techniques and system biology approaches to engineer and analyse yeast cell factories. There are two biosynthesis pathways of resveratrol, starting from tyrosine or phenylalanine, which in this thesis...... are defined as the TAL pathway and PAL pathway respectively. For the TAL pathway, I collaborated with Christian Bille Jendresen, Steen Gustav Stahlhut to screen fourteen diverse heterologous tyrosine ammonia lyases (TALs) for their activity in yeast and E. coli. I expressed the 14 TALs in S. cerevisiae...

  1. Apolipoprotein E-epsilon 4 frequency in affective disorder

    DEFF Research Database (Denmark)

    Kessing, L V; Jørgensen, O S

    1999-01-01

    -Bråne-Steen Dementia Rating Scale, and the Global Deterioration Scale. RESULTS: The frequency of APOE-epsilon 4 allele was approximately the same in unipolar patients (.189) and in bipolar patients (.167). Although patients showed more cognitive impairment than controls, no significant overall difference was found...... was found with gender, age at onset, the number of affective episodes, the presence of psychotic features, or the prevalence of familial affective disorder. CONCLUSIONS: It seems that cognitive impairment in affective disorder can be attributed to pathways other than the APOE genotype.......BACKGROUND: The epsilon 4 allele of apolipoprotein E (APOE) as well as affective disorder have been found to be associated with Alzheimer's disease, but it is unclear whether cognitive impairment in affective disorder or subtypes of affective disorder is mediated by the epsilon 4 allele of APOE...

  2. Landscape by Moonlight: Peter Paul Rubens and Astronomy

    Science.gov (United States)

    Mendillo, M.

    2016-01-01

    In the last years of his life, Rubens (1577-1640) lived happily with his wife and children on his Het Steen estate. During this period he worked and reworked a painting that had special meaning to him—Landscape by Moonlight (1635-40), now at the Courtauld Gallery in London. After a highly successful career painting religious and secular portraits, allegories, and occasional landscapes, Rubens put an extraordinary amount of effort into this final landscape. He was well known as a person who would commit to memory ideas and themes that he would use in future works. This paper reviews Rubens' attention to the visualization of nature, his personal connections to Elsheimer, Galileo, and Peiresc, and explores his possible depiction of constellations recalled from memory and placed within the cloudy skies in his Landscape by Moonlight.

  3. Rumlig kultur / Spatial Culture

    DEFF Research Database (Denmark)

    RUMLIG KULTUR / SPATIAL CULTURE præsenterer et humanvidenskabeligt livtag med storbyens erfaringsverden. Emnerne for 21 kapitler spænder fra billedhuggeren Bjørn Nørgaard og boligbyggeriet Bispebjerg Bakke til stedsopfattelsen i moderne guidebøger. Undervjs inddrages bykulturens tænkere såsom Steen...... artikler et forskningsfelt for rumlig kultur, hvori alskens sanse- og refleksionsformer finder sammen. Based in humanistic urban studies as practiced in the Department of Arts and Cultural Studies, University of Copenhagen, SPATIAL CULTURE outlines a novel framework for understanding the social...... and cultural environments of the modern and contemporary metropolis. The contributions focus on urban and suburban cultures of Copenhagen, New York, Hong Kong, Berlin and anderswo, demonstrating how the precise analysis of cultural and artistic phenomena informs a multilayered understanding...

  4. Community in Credit Unions: Has banking regulationimpaired CSR in Australian Customer Owned Banks?

    Directory of Open Access Journals (Sweden)

    Dianne McGrath

    2017-02-01

    Full Text Available This paper presents a sector scan of a sample of Australian Credit Unions and Mutual Banks to examine the CSR reporting from the perspective of the three pillars model proposed by vanOorschot, de Hoog, van der Steen and van Twist (2013. It is argued that the pillar requiringco-operatives to ensure activities which ‘aim for change’, should promote increasing adoptionof CSR. The paper theorises that regulatory requirements imposed in Australia on all bankinginstitutions carry a higher proportional cost to the customer owned banking sector than theshareholder based commercial banks. This consumption of the limited financial resourcesavailable in this sector of banking services, are inhibiting regional Customer Owned Bankingproviders, as co-operative organisations, to fulfil the required co-operative principle to instigatechange for the betterment of communities. This failure could signal the demise of some entitiesin the jurisdiction of Customer Owned Banking.

  5. Quantum independent increment processes

    CERN Document Server

    Franz, Uwe

    2006-01-01

    This is the second of two volumes containing the revised and completed notes of lectures given at the school "Quantum Independent Increment Processes: Structure and Applications to Physics". This school was held at the Alfried-Krupp-Wissenschaftskolleg in Greifswald in March, 2003, and supported by the Volkswagen Foundation. The school gave an introduction to current research on quantum independent increment processes aimed at graduate students and non-specialists working in classical and quantum probability, operator algebras, and mathematical physics. The present second volume contains the following lectures: "Random Walks on Finite Quantum Groups" by Uwe Franz and Rolf Gohm, "Quantum Markov Processes and Applications in Physics" by Burkhard Kümmerer, Classical and Free Infinite Divisibility and Lévy Processes" by Ole E. Barndorff-Nielsen, Steen Thorbjornsen, and "Lévy Processes on Quantum Groups and Dual Groups" by Uwe Franz.

  6. Complex Strategic Choices Applying Systemic Planning for Strategic Decision Making

    CERN Document Server

    Leleur, Steen

    2012-01-01

    Effective decision making requires a clear methodology, particularly in a complex world of globalisation. Institutions and companies in all disciplines and sectors are faced with increasingly multi-faceted areas of uncertainty which cannot always be effectively handled by traditional strategies. Complex Strategic Choices provides clear principles and methods which can guide and support strategic decision making to face the many current challenges. By considering ways in which planning practices can be renewed and exploring the possibilities for acquiring awareness and tools to add value to strategic decision making, Complex Strategic Choices presents a methodology which is further illustrated by a number of case studies and example applications. Dr. Techn. Steen Leleur has adapted previously established research based on feedback and input from various conferences, journals and students resulting in new material stemming from and focusing on practical application of a systemic approach. The outcome is a coher...

  7. Composers on Stage: Ambiguous Authorship in Contemporary Music Performance

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2016-01-01

    In recent years, workflows within the field of contemporary classical music have changed drastically. Increasingly, composers are active in the process of creating and co-creating performances, not only the auditory dimensions but also the visual design and theatrical staging. The practice has...... but involving themselves in other ways. The article explores the ambivalent authorship at stake in these performances, arguing that they appear to be projects that reveal the processes of musical performance in ways that undermine the Romantic idea of the composer while concurrently celebrating that very same...... idea through their exposition and staging of the composer. The examples used to illustrate my argument are analyses of All the Time (Hodkinson, 2001), Buenos Aires (Steen-Andersen 2014) and Ord for Ord (Rønsholdt, 2014)...

  8. Testing for direct genetic effects using a screening step in family-based association studies

    Directory of Open Access Journals (Sweden)

    Sharon M Lutz

    2013-11-01

    Full Text Available In genome wide association studies (GWAS, families based studies tend to have less power to detect genetic associations than population based studies, such as case-control studies. This can be an issue when testing if genes in a family based GWAS have a direct effect on the phenotype of interest or if the genes act indirectly through a secondary phenotype. When multiple SNPs are tested for a direct effect in the family based study, a screening step can be used to minimize the burden of multiple comparisons in the causal analysis. We propose a 2-stage screening step that can be incorporated into the family based association test (FBAT approach similar to the conditional mean model approach in the VanSteen-algorithm [1]. Simulations demonstrate that the type 1 error is preserved and this method is advantageous when multiple markers are tested. This method is illustrated by an application to the Framingham Heart Study.

  9. Drone Age Cinema

    DEFF Research Database (Denmark)

    Christiansen, Steen Ledet

    such physical movements and responses through vectors, droning, kinetics, telesomatics and volatility and in so doing unveils new modes of perception that acclimatise us for warfare. Drawing on theories from film-philosophy and a consideration of the aesthetics and phenomenology of war, this is an innovative......At a time when technological advances are transforming cultures and supporting new automated military operations, action films engage the senses and, in doing so, allow viewers to embody combat roles. This book argues that through film the viewer adapts to an ecology of fear, one that reflects...... global panic at the near-constant threat of conflict and violence. Often overwhelming in its audiovisual assault, action cinema attempts to overpower our bodies with its own through force and intensity. In this book, Steen Ledet Christiansen identifies five aspects central to how action films produce...

  10. Compilation of requests for nuclear data. Addendum

    International Nuclear Information System (INIS)

    1984-09-01

    Each request is assigned a unique identifying number. The first two digits of this number give the year the request was initiated. All requests for a given Isotope and Quantity are grouped (or blocked) together. The requests in a block are followed by any status comments. Each request has a unique Isotope, Quantity and Requester. The requester is identified by laboratory, last name, and sponsoring US government agency, e.g., BET, Steen, DNR. All requests must give the energy (or range of energy) for the incident particle when appropriate. The accuracy needed in percent is also given. The error quoted is assumed to be 1-sigma at each measured point in the energy range requested unless a comment specifies otherwise. Sometimes a range of accuracy indicated by two values is given or some statement is given in the free text comments. An incident energy resolution in percent is sometimes given

  11. Elaphostrongylus spp. from Scandinavian cervidae - a scanning electron microscope study (SEM

    Directory of Open Access Journals (Sweden)

    Margareta Stéen

    1990-08-01

    Full Text Available Nematodes of the genus Elaphostrongylus collected from moose (Alces alces L., reindeer (Rangifer tarandus tarandus L., and red deer (Cervus elaphus L., respectively, were studied by means of scanning electron microscopy. Morphological differences in the ribs of the genital bursa were demonstrated. The Elaphostrongylus species from reindeer and red deer differed from each other in four ribs of the genital bursa. These results agree with the morphological characters of E. cervi and E. rangiferi described by Cameron (1931 and Mitskevitch (1960. The genital bursa of Elaphostrongylus sp. from moose, in accordance with the description of E. alces by Steen et al. (1989 showed characteristics differing from those found in Elaphostrongylus spp. from reindeer and red deer respectively. These results support the hypothesis that there are three separate species of Elaphostrongylus present in Scandinavian Cervidae. Svep-elektroniska studier på Elaphostrongylus spp. hos skandinaviska hjortdjur.Abstract in Swedish / Sammandrag: Rundmaskar inom slaktet Elaphostrongylus funna hos alg (Alces alces L., ren (Rangifer tarandus tarandus L. och kronhjort(Cervus elaphus L. studerades med hjalp av svepelelektronmikroskop. De hanliga bursorna med sin a stodjeribbor uppvisade variationer i utseende, langd och placering mellan dessa rundmaskar. De arter av Elaphostrongylus funna hos ren och kronhjort skilde sig åt avseende fyra stodjeribbor på de hanliga bursorna. Dessa resultat stammer val overens med de karaktarer som tidigare ar beskrivna av Cameron(1931 och av Mitskevich (1960. Den hanliga bursan hos arten Elaphostrongylus funnen hos alg, vilken tidigare ar beskriven av Steen et al. (1989, visade upp ett utseende som skilde sig från bursorna hos de Elaphostrongylus-arter funna hos ren och kronhjort. Dessa resultat stoder hypotesen om tre skilda arter av Elaphostrongylus hos skandinaviska hjortdjur.

  12. Directional change during a Miocene R-N geomagnetic polarity reversal recorded by mafic lava flows, Sheep Creek Range, north central Nevada, USA

    Science.gov (United States)

    Bogue, S. W.; Glen, J. M. G.; Jarboe, N. A.

    2017-09-01

    Recurring transitional field directions during three Miocene geomagnetic reversals provide evidence that lateral inhomogeneity of the lower mantle affects flow in the outer core. We compare new paleomagnetic results from a composite sequence of 15.2 Ma lava flows in north central Nevada (Sheep Creek Range; 40.7°N, 243.2°E), erupted during a polarity reversal, to published data from Steens Mountain (250 km to the northwest in Oregon) and the Newberry Mountains (650 km to the south in California) that document reversals occurring millions of years and many polarity switches earlier. Alternating field demagnetization, followed by thermal demagnetization in half the samples, clearly isolated the primary thermoremanent magnetization of Sheep Creek Range flows. We correlated results from our three sampled sections to produce a composite record that begins with a single virtual geomagnetic pole (VGP) at low latitude in the Atlantic, followed by two VGPs situated near latitude 30°N in NE Africa. After jumping to 83°N (one VGP), the pole moves to equatorial South America (one VGP), back to NE Africa (three VGPs), to high southern latitudes (two VGPs), back to equatorial South America (three VGPs), and finally to high northern latitudes (nine VGPs). The repeated visits of the transitional VGP to positions in South America and near NE Africa, as well as the similar behavior recorded at Steens Mountain and the Newberry Mountains, suggest that lower mantle or core-mantle boundary features localize core flow structures, thereby imparting a discernible regional structure on the transitional geomagnetic field that persists for millions of years.

  13. Huysmans e Gonzaga Duque: transposições de arte em textos franceses e brasileiros do Simbolismo

    Directory of Open Access Journals (Sweden)

    André Soares Vieira

    2013-12-01

    Full Text Available Este ensaio pretende refletir sobre alguns processos de tradução de obras picturais transpostas para textos críticos e literários. O processo de transposição escrita da pintura será examinado segundo uma análise do discurso sobre arte produzido pelo escritor e crítico brasileiro Gonzaga Duque (1863-1911 e pelo romancista e também crítico de arte francês Joris-Karl Huysmans (1848- 1907. O objetivo é o de mapear, através de obras dos pintores Matthias Grünewald (1470-1528 e Félicien Rops (1833-1898, alguns modos de transferência entre a arte pictórica e os textos críticos e literários, tomando-se por base, sobretudo, os estudos de Françoise Lucbert.

  14. Evolution of new superconductors. Past, present and future

    International Nuclear Information System (INIS)

    Akimitsu, Jun

    2011-01-01

    I present here the past and present situations of new superconductors and also the future prospect. Superconductivity has started since Kamerlingh Onnes first observed the zero resistivity. After that, the critical temperature T c was gradually increased. In the early stage of superconductive material investigations, main contribution has been made by B. Matthias and his group. In 1986, a new superconductor La-Ba-Cu-O, which belongs to new category in the superconducting society, has been found by Bednorz and Mueller. After that T c 's have been drastically increased, and finally reached to T c - 164 K in the Hg-compound. Next, I review several new superconductors discovered within 20 years. Finally, I mention my personal perspective to a high-T c superconductor. (author)

  15. String-math 2012

    CERN Document Server

    Katz, Sheldon; Klemm, Albrecht; Morrison, David R

    2015-01-01

    This volume contains the proceedings of the conference String-Math 2012, which was held July 16-21, 2012, at the Hausdorff Center for Mathematics, Universitat Bonn. This was the second in a series of annual large meetings devoted to the interface of mathematics and string theory. These meetings have rapidly become the flagship conferences in the field. Topics include super Riemann surfaces and their super moduli, generalized moonshine and K3 surfaces, the latest developments in supersymmetric and topological field theory, localization techniques, applications to knot theory, and many more. The contributors include many leaders in the field, such as Sergio Cecotti, Matthias Gaberdiel, Rahul Pandharipande, Albert Schwarz, Anne Taormina, Johannes Walcher, Katrin Wendland, and Edward Witten. This book will be essential reading for researchers and students in this area and for all mathematicians and string theorists who want to update themselves on developments in the math-string interface.

  16. Interferons and their potential in the treatment of ocular inflammation

    Directory of Open Access Journals (Sweden)

    Friederike Mackensen

    2009-10-01

    Full Text Available Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Zürich, SwitzerlandAbstract: Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice.Keywords: interferon, uveitis, treatment, inflammation

  17. Comparative DEMS study on the electrochemical oxidation of carbon blacks

    DEFF Research Database (Denmark)

    Ashton, Sean James; Arenz, Matthias

    2012-01-01

    Publication year: 2012 Source:Journal of Power Sources, Volume 217 Sean J. Ashton, Matthias Arenz The intention of the study presented here is to compare the electrochemical oxidation tendencies of a pristine Ketjen Black EC300 high surface area (HSA) carbon black, and four graphitised counterparts...... heat-treated between 2100 and 3200 °C, such as those typically used as corrosion resistant carbon (CRC) supports for polymer electrolyte membrane fuel cell (PEMFC) catalysts. A methodology combining cyclic voltammetry (CV) and differential electrochemical mass spectrometry (DEMS) is used, which allows......; however, CRC samples graphitised =2800 °C did not exhibit this same behaviour. Highlights ¿ We quantitatively determine electrooxidation of carbon support materials. ¿ We can distinguish between the total and partial electrooxidation. ¿ Non or mildly heat treated carbon forms passivating layer. ¿ Heat...

  18. Prestigious US awards for CERN computing

    CERN Multimedia

    2001-01-01

    On 4 June in the distinguished surroundings of Washington's National Building Museum, IT Deputy Division Leader Les Robertson accepted a 21st Century Achievement Award from the Computerworld Honors Program on behalf of CERN. This prestigious award was made to CERN for its innovative application of information technology to the benefit of society. Members of the team that initiated the SHIFT project with the Computerworld trophy. The team was a collaboration between the Information Technology Division, the OPAL experiment and Indiana University. From left to right, Ben Segal, Matthias Schroeder, Gail Hanson, Bernd Panzer, Jean-Philippe Baud, Les Robertson and Frédéric Hemmer. CERN's award followed the Laboratory's nomination by Lawrence Ellison, Chairman and CEO of the Oracle Corporation. Ellison nominated CERN in recognition of 'pioneering work in developing a large scale data warehouse' - an innovative computing architecture that responds precisely to the global particle physics commun...

  19. Kaunistatud elamu / Krista Kodres

    Index Scriptorium Estoniae

    Kodres, Krista, 1957-

    2005-01-01

    Eestis 16.-18. sajandil. Etikud ja trepid. Burchardi piltetikud (1630.-1640. aastad, Arent Passer?). Fassaadiportaalid (A. Passer, Dionysius Passer, Berent Geistman). Narva ja Pärnu portaalid (Matthias Daus, Otto Koste, Jan van der Capelle).Uued uksed (Elert Thiele töökoda, Abraham Friedrich Pahlmann). "Pildid" fassaadil (A. Passeri töökoda). Passeri voorused ja protestantlik eetika (A. Passeri töökoda, Jakob Damm)). Viilukivid (Hans Damm, Jakob Damm, Winant Nacke, Johann Georg Heroldt). Siseportaalid (Clemens Pale, A. Passer, Christian Ackermann). Thomas von zur Mühleni maja siseportaal (1687). Kaunistatud aken (A. Passeri ja W. Nacke töökojad). Kamin. Paraadne trepp. Bibliograafia lk. 446-448

  20. Enhancing undergraduate students’ communications skills

    DEFF Research Database (Denmark)

    Jørgensen, Merete; Witt, Klaus; Fridorff-Jens, Peter Kindt

    2014-01-01

    ,Monika Bullinger,Matthias Rose, Sylke Andreas.Enhancing medical students' communication skills: development and evaluation of an undergraduate training program.Published online 2012 March 24. doi: 10.1186/1472-6920-12-16 2.William T. Branch, Jr, MD; David Kern, MD; Paul Haidet, MD, MPH; Peter Weissmann, MD......19729 Abstract Title: Enhancing undergraduate students communications skills Abstract Authors: •Merete Jorgensen, Copenhagen University , Family Medicine , Copenhagen •Klaus Witt, Research Unit , Family Medicine , Copenhagen •Peter Kindt Fridorff-Jens, Copenhagen University , IT-unit , Copenhagen...... Abstract Presenter(s): •Merete Jorgensen, Copenhagen University , Family Medicine , Øster Farigmagsgade 5 , 1014 , K , Denmark , mejor@sund.ku.dk Abstract: Background Being teachers in Clinical Course of Family Medicine since 1995, we have developed two schemes for communication analysing purposes called...

  1. DEGRADATION WORKS OF MONUMENTAL ART CAST BRONZE UNDER THE INFLUENCE OF ENVIRONMENTAL FACTORS

    Directory of Open Access Journals (Sweden)

    Delia NICA-BADEA

    2012-11-01

    Full Text Available Intensive pollution, combined with the lack of conservation of monuments exposed to these environments make the main cause of deterioration of cultural objects to atmospheric corrosion metal. This paper proposes a study of the main factors leading to degradation Bronze alloy, cast bronze monuments exposed to open atmosphere: corrosive environmental factors, stability and products of corrosion of bronze. In general, all corrosion products present on a metal surface are indicated as 'skate', can be composed of single-layer or multilayer products. The paper also includes a case study on the influence of environmental factors on degradation Matthias monument statue in Cluj-Napoca, Romania. Visual inspection of the monument informs us that have white spots, gray, reddish not consistent with the base color green patina, surfaces showing depigmentation, the rain washed areas, crystallization, deposition of air-borne particles.

  2. Optimized construction of biogas plants; Optimierte Bauweise fuer Biogasanlagen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-19

    Within the conference of the International Trade Fair for Biogas Plant Technology at 21st February, 2012 in Berlin, the following lectures were held: (1) Optimized dimensions of containers for small systems of liquid manure (Manfred Thalmann); (2) Microferm mini biogas plants (Bart Brouwer); (3) Fermentation of stackable biomass in rural biogas plant - The DeNaBa system (Christian Deterding); (4) The Sauter Biogas System for the fermentation of liquid manure, solid dung, and other residual materials (Stefan Sauter); (5) Bio-electricity: Controllable power generation by means of biogas plants (Matthias Sonnleitner); (6) Reduction of the effort and increase of the yield using UDR fixed bed technology (Alfred van den Berg); (7) Prestressed concrete container for biogas plants: Area of application - quality - options (Harald Feldmann); (8) Corrosion protection of agricultural and communal biogas plants (Michael Normann); (9) Fundamentals of efficient and effective flow generation in biogas plants (Kay Rotalski); (10) Rotary piston screw pistons and eccentric screw pumps (Thorsten Gilles).

  3. From the CERN web: Collide@CERN, Fermilab neutrinos and more

    CERN Multimedia

    2015-01-01

    This new section highlights articles, blog posts and press releases published in the CERN web environment over the past weeks. This way, you won’t miss a thing...   Ruth Jarman and Joe Gerhardt. (Photo: Matthias H. Risse). Collide@CERN Ars Electronica Award goes to “Semiconductor” 10 August – Collide@CERN Ruth Jarman and Joe Gerhardt, two English artists collaborating under the name Semiconductor, are this year’s recipients of the Collide@CERN Ars Electronica Award. In the coming months, they will begin a two-month residency at CERN.  Continue to read…     Illustration: Fermilab/Sandbox Studio.   Fermilab experiment sees neutrinos change over 500 miles 7 August - Fermilab press release Scientists on the NOvA experiment saw their first evidence of oscillating neutrinos, confirming that the extraordinary detector built for the project not only functions as planned but is also making great p...

  4. Current contributions on the technical thermodynamics, power engineering and district heating supply. Special publication; Aktuelle Beitraege zur technischen Thermodynamik, Energietechnik und Fernwaermeversorgung. Sonderveroeffentlichung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-03-15

    Within the special publication under consideration, the German Heat and Power Association (Frankfurt (Main), Federal Republic of Germany) presents the following current contributions on the technical thermodynamics, power engineering and district heating supply: (1) Cellular metallic materials for innovative latent heat accumulator technologies (Jens Meinert); (2) Compressed air storage - technology, chances and problems (Rutger Kretschmer); (3) KWK electricity - Identification and evaluation (Matthias Krause); (4) Investigation of the storage ability of district heating grids and implementation into the optimized planning of heat generators (Sebastian Gross); (5) Autarcic thermal densification to the combined heat and power and cooling production? - A fundamental thermodynamic consideration (Torben Moeller); (6) Modelling of cogeneration power plants - Investigation of the transformation opportunity of existing district heating systems in LowEx grids (Martin Rhein); (7) Discrete building model for the dynamic thermohydraulic simulation of district heating (Dominik Haas); (8) Ventilation and degasification of solar power plants (Karin Ruehling); (9) Integral simulation of district heating with TRNSYS-TUD (Steffen Robbi); (10) Theoretical analyses of return temperatures in building heating networks (Andreas Meinzenbach); (11) Municipal energy efficiency as an important contribution to the reduction of greenhouse gas emissions (Matthias Mischke); (12) Investigation of the latent heat storage system PK 6 for use in air-conditioning installations (Sebastian Pinnau); (13) The role of the thermodynamics in the electromobility (Lars Schinke); (14) Flow and heat transfer in cooling channels with methane (Andre Schlott); (15) Numerical calculations of stoves fired with wooden logs (Ulf Senechal); (16) Supply of thermodynamic substance data for working fluids of power engineering (Hans-Joachim Kretzschmar); (17) Cyclic pipe-ground interaction in solar-thermal heat grids

  5. Musikterapiuddannelsen 25 år - Festskrift

    DEFF Research Database (Denmark)

    musikterapeutisk hovedinstrument?  - ændrede studieordninger på musikterapiuddannelsen Lars Ole Bonde: Studieordningen af 2006 i praksis. Erfaringer fra det første år Carl Bergstrøm-Nielsen: En ny musikfaglighed Britta Kvist: Mit liv som UA'er i 24 år Niels Hannibal: Når teori og praksis lever side om side Tony...... Wigram: Doctoral Research School in Music Therapy, Aalborg University Lars Ole Bonde: Forskerskolen i musikterapi - en international succes Peder Kaj Pedersen: Musikterapeutiske forskningsstrategier. Profane replikker fra sidelinien Anne Steen Møller: "Musikterapeut? Hvor spændende! Hvad laver sådan én......?" Helga Pallesen: En ældre studerende på en ung uddannelse Lis Karlsen & Anne Eijgendaal: En historie om hvordan musikterapeuterne blev fagligt organiserede Hanne Mette Ridder: Hvor går kandidaterne hen, når de går ud?           Musiksatser af bl.a. Bo Hulgaard, Bjørn Veierskov Alexandersson, og Carl...

  6. Die Clarens-inspirasie en ruimtebeelding in Plek van die bruin geeste (Elsabe Steenberg

    Directory of Open Access Journals (Sweden)

    B. van der Westhuizen

    1998-04-01

    Full Text Available Clarens as literary inspiration. The depiction of space in Elsabe Steenberg’s novel Plek van die bruin geeste (Place of the brown spirits It is clear that much of Elsabe Steen berg’s artistic work was inspired by the mountainous Clarens in the Eastern Free State. Such is the case with her 1975 novel for adults - Plek van die bruin geeste (Place of the brown spirits. In this novel a city girl is abducted by a young man, an individualistic, outsider character who wants to get money to leave South Africa for a place like an island in the Pacific where race and colour will not be of such crucial importance as in South Africa. The importance of the possibilities of inner healing of the human being by spending time in nature is represented in this novel in the finest detail in various narrative patterns. The intention of the author is represented in a fundamentalist view of reality, namely that God is the Origin, the Giver of insight into the diversity, interrelatedness and meaning of reality, and that God is the real regenerating Force.

  7. Regional cerebral blood flow and its correlation with clinical assessment in senile dementia of Alzheimer type and multi-infarct dementia. A study with SPECT using sup 133 Xe inhalation method

    Energy Technology Data Exchange (ETDEWEB)

    Shinohara, Masao; Kawakatsu, Shinobu; Morinobu, Shigeru; Oiji, Arata; Sagawa, Katsuo; Yazaki, Mitsuyasu; Totsuka, Shirou; Komatani, Akio; Yamaguchi, Koichi [Yamagata Univ. (Japan). Faculty of Medicine

    1989-09-01

    Twenty-one patients with senile dementia of Alzheimer type (SDAT), 11 patients with multi-infarct dementia (MID), and 6 healthy volunteers were examined by SPECT using Xe-inhalation method. These patients also underwent an intelligence test according to the Gottfries-Brane-Steen (GBS) scale. Patients with mild SDAT did not have a significantly decreased regional cerebral blood flow (rCBF). In moderate or severe cases, however, a significantly decreased rCBF was bilaterally observed in all regions, except for the basal ganglia. This was marked in the temporoparietal region. A group of moderate or severe MID patients had a significantly decreased rCBF especially in the basal ganglia. It was also observed in the temporoparietal region, but not in the frontal region. Among the SDAT patients, there was a good correlation between rCBF and GBS scale in all the regions, except for the basal ganglia. In the case of MID patients, correlations were observed both between rCBF in the left side of the brain and clinical findings according to the method of Hasegawa and between rCBF in the right side of the frontal region and the motor function on the GBS scale. These findings may have implications for the different pathophysiology between SDAT and MID. (N.K.).

  8. Los desequilibrios regionales en España

    Directory of Open Access Journals (Sweden)

    Tomás Franco Aliaga

    1990-01-01

    Full Text Available Regional inequialities have always existed as can be steen throughout Spanish Economic History. Until well into the Modern Age, inland Spain contained two tliirds of tlie population and yielded most of tlie resources. However, the capitalist system and the free market exarcerbate such inequalities because of their own dynamics, polarizing resources in order to obtain the highest profit. The consequences of this, seen from the geographical point of view, are a migrant population, environnnental changes, urban growth, and the adoption of new forma of spatial organization, among others. Between 1960-1973 the country witnessed a «miraculous» economic growth rate and as such there was a widespread and significant backward movement with important effects in the more industrially developed regions. The economic recovery (1986-1989 maintains such inequalities although the development axes spread in a «4» form which embraces the Valle del Ebro (Ebro Valley, the mediterranean arch from Gerona (Nort Cataluña to Málaga (South-East Andalucía and both archipielagos and Madrid, which still is the well established reference point in present-day Spain and its autonomous regions.

  9. Regional cerebral blood flow and its correlation with clinical assessment in senile dementia of Alzheimer type and multi-infarct dementia

    International Nuclear Information System (INIS)

    Shinohara, Masao; Kawakatsu, Shinobu; Morinobu, Shigeru; Oiji, Arata; Sagawa, Katsuo; Yazaki, Mitsuyasu; Totsuka, Shirou; Komatani, Akio; Yamaguchi, Koichi

    1989-01-01

    Twenty-one patients with senile dementia of Alzheimer type (SDAT), 11 patients with multi-infarct dementia (MID), and 6 healthy volunteers were examined by SPECT using Xe-inhalation method. These patients also underwent an intelligence test according to the Gottfries-Brane-Steen (GBS) scale. Patients with mild SDAT did not have a significantly decreased regional cerebral blood flow (rCBF). In moderate or severe cases, however, a significantly decreased rCBF was bilaterally observed in all regions, except for the basal ganglia. This was marked in the temporoparietal region. A group of moderate or severe MID patients had a significantly decreased rCBF especially in the basal ganglia. It was also observed in the temporoparietal region, but not in the frontal region. Among the SDAT patients, there was a good correlation between rCBF and GBS scale in all the regions, except for the basal ganglia. In the case of MID patients, correlations were observed both between rCBF in the left side of the brain and clinical findings according to the method of Hasegawa and between rCBF in the right side of the frontal region and the motor function on the GBS scale. These findings may have implications for the different pathophysiology between SDAT and MID. (N.K.)

  10. Formidlings-DVD om musikterapi

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Hannibal, Niels; Wigram, Tony

    2010-01-01

    betydelige funktionsnedsættelser Case 1.1: Joel 7 år (Wigram) assessment, autisme Case 1.2: Andreas 10 år (Rydahl) metal retardering Case 1.3: Julie 11 år (Andersen) forsinket udvikling, opmærksomhedsproblemer Case 1.4: Mark 15 år (Rydahl) autisme, blindhed Case 1.5: Jeppe 15 år (Rydahl) spastisk lammelse......, opmærksomhedsforstyrrelse Case 1.6: Michael 19 år (Karlsen) autisme, mental retardering Case 1.7: Hanne 19 år (Karlsen) mental retardering, autistiske træk Case 1.8: Gruppe, teenagere (Rydahl) betydelige funktionsnedsættelser Serie 2: Musikterapi med personer inden for det psykiatriske behandlingsområde Case 2.1: Lisa 14....... Hospice Case 6.3: Musikalsk miljø (Majlund) miljøterapeutisk brug af musik. Bonusmateriale Video 7.1: Demens Creative Souls af Stine Wold Video 7.2: Funktionsnedsættelse En stemme til Stefan af Mette Egelund Olsen & Anne Steen Video 7.3: Aspergers syndrom Timothy (4 år) af Amelia Oldfield Video 7.4: Rett...

  11. Do positive psychology exercises work? A replication of Seligman et al. (2005).

    Science.gov (United States)

    Mongrain, Myriam; Anselmo-Matthews, Tracy

    2012-04-01

    The current work replicated a landmark study conducted by Seligman and colleagues (2005) that demonstrated the long-term benefits of positive psychology exercises (PPEs). In the original study, two exercises administered over 1 week ("Three Good Things" and "Using your Signature Strengths in a New Way") were found to have long-lasting effects on depression and happiness (Seligman, Steen, Park, & Peterson, 2005). These exercises were tested here using the same methodology except for improvements to the control condition, and the addition of a second "positive placebo" to isolate the common factor of accessing positive, self-relevant constructs. This component control design was meant to assess the effect of expectancies for success (expectancy control), as well the cognitive access of positive information about the self (positive placebo). Repeated measures analyses showed that the PPEs led to lasting increases in happiness, as did the positive placebo. The PPEs did not exceed the control condition in producing changes in depression over time. Brief, positive psychology interventions may boost happiness through a common factor involving the activation of positive, self-relevant information rather than through other specific mechanisms. Finally, the effects of PPEs on depression may be more modest than previously assumed. © 2012 Wiley Periodicals, Inc.

  12. A roadmap to peace. Journey metaphors in political speeches on the Middle East peace process

    Directory of Open Access Journals (Sweden)

    Assunta Caruso

    2014-07-01

    Full Text Available Abstract – This paper investigates the metaphorical conceptualization of peace by former leaders George W. Bush, Ariel Sharon, and Mahmoud Abbas. Specifically, it examines how peace/the peace process is conceptualized via metaphors through the notion of JOURNEY and MOVEMENT. The corpus in this study comprises twenty speeches given by the three politicians over a four-year period (2002-2005. The corpus data is analyzed using a combination of different methods. The tools are mainly Conceptual Metaphor Theory (Lakoff and Johnson 1980, the MIPVU procedure (Steen et al. 2010, and Critical Metaphor Analysis (Charteris-Black 2004. Findings reveal that JOURNEY metaphors are a vital and common part of the three politicians’ political discourse. Overall, there are very few metaphors for peace unique to the individual politicians. The main differences observed lie not in which metaphors are used, but in what aspects of peace or the peace process they are used to highlight.Keywords: metaphor identification, conceptual metaphor, Critical Metaphor Analysis, political discourse, peace.

  13. Slug flow transitions in horizontal gas/liquid two-phase flows. Dependence on channel height and system pressure for air/water and steam/water two-phase flows

    International Nuclear Information System (INIS)

    Nakamura, Hideo

    1996-05-01

    The slug flow transitions and related phenomena for horizontal two-phase flows were studied for a better prediction of two-phase flows that typically appear during the reactor loss-of-coolant accidents (LOCAs). For better representation of the flow conditions experimentally, two large-scaled facility: TPTF for high-pressure steam/water two-phase flows and large duct test facility for air/water two-phase flows, were used. The visual observation of the flow using a video-probe was performed in the TPTF experiments for good understanding of the phenomena. The currently-used models and correlations based mostly on the small-scale low-pressure experiments were reviewed and improved based on these experimental results. The modified Taitel-Dukler model for prediction of transition into slug flow from wavy flow and the modified Steen-Wallis correlation for prediction of onset of liquid entrainment from the interfacial waves were obtained. An empirical correlation for the gas-liquid interfacial friction factor was obtained further for prediction of liquid levels at wavy flow. The region of slug flow regime that is generally under influences of the channel height and system pressure was predicted well when these models and correlations were applied together. (author). 90 refs

  14. Video- or text-based e-learning when teaching clinical procedures? A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Buch SV

    2014-08-01

    Full Text Available Steen Vigh Buch,1 Frederik Philip Treschow,2 Jesper Brink Svendsen,3 Bjarne Skjødt Worm4 1Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark; 2Department of Anesthesia and Intensive Care, Herlev Hospital, Copenhagen, Denmark; 3Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; 4Department of Anesthesia and Intensive Care, Bispebjerg Hospital, Copenhagen, Denmark Background and aims: This study investigated the effectiveness of two different levels of e-learning when teaching clinical skills to medical students. Materials and methods: Sixty medical students were included and randomized into two comparable groups. The groups were given either a video- or text/picture-based e-learning module and subsequently underwent both theoretical and practical examination. A follow-up test was performed 1 month later. Results: The students in the video group performed better than the illustrated text-based group in the practical examination, both in the primary test (P<0.001 and in the follow-up test (P<0.01. Regarding theoretical knowledge, no differences were found between the groups on the primary test, though the video group performed better on the follow-up test (P=0.04. Conclusion: Video-based e-learning is superior to illustrated text-based e-learning when teaching certain practical clinical skills. Keywords: e-learning, video versus text, medicine, clinical skills

  15. 'Made in Europe' photovoltaic industry Conference - perspectives in the face of the crisis?'

    International Nuclear Information System (INIS)

    Masson, Gaetan; Goeke, Berthold; Barber, Nicolas; Frey, Peter; Laborde, Eric; Michael Lippert; Matthias Reichmuth; Daniel Lincot

    2011-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on the future of the photovoltaic industry. In the framework of this French-German exchange of experience, about 120 participants exchanged views on some innovative projects, as well as some solutions to grid integration and electricity storage. The question of anticipated grid parity through self-consumption was addressed too. This document brings together the available presentations (slides) made during this event: 1 - PV, a competitive source of energy in Europe: tomorrows' grid parity and markets in Europe (Gaetan Masson); 2 - Photovoltaics support in Germany - developments and challenges (Berthold Goeke); 3 - New support mechanism to the photovoltaic industry: optimizing the model, the French market asset (Nicolas Barber); 4 - PV production in Germany - threats and opportunities (Peter Frey); 5 - PV Alliance - From Labs to Fabs: ensuring the photovoltaic industry future through innovation and R and D collaborations in France and Germany (Eric Laborde); 6 - Smart energy storage improving grid integration of decentralized PV energy (Michael Lippert); 7 - Onsite Consumption - the anticipated Grid Parity (Matthias Reichmuth); 8 - The photovoltaic energy research and development institute - IRDeP (Daniel Lincot)

  16. Mining Tacitus: secrets of empire, nature and art in the reason of state.

    Science.gov (United States)

    Keller, Vera

    2012-06-01

    A new political practice, the 'reason of state', informed the ends and practices of natural study in the late sixteenth century. Informed by the study of the Roman historian Tacitus, political writers gathered 'secrets of empire' from both history and travel. Following the economic reorientation of 'reason of state' by Giovanni Botero (1544-1617), such secrets came to include bodies of useful particulars concerning nature and art collected by an expanding personnel of intelligencers. A comparison between various writers describing wide-scale collections, such as Botero, Francis Bacon (1561-1626), Jakob Bornitz (1560-1625) and Matthias Bernegger (1582-1640), reveals that seventeenth-century natural intelligencers across Europe not only were analogous to political intelligencers, but also were sometimes one and the same. Those seeking political prudence cast themselves as miners, prying precious particulars from the recesses of history, experience and disparate disciplines, including mathematics, alchemy and natural philosophy. The seventeenth-century practice of combining searches for secrets of empire, nature and art contests a frequent historiographical divide between empirical science and Tacitism or reason of state. It also points to the ways political cunning shaped the management of information for both politics and the study of nature and art.

  17. Cultural relations between Hungary and Albania during the period of Humanism and Renaissance

    Directory of Open Access Journals (Sweden)

    Muhamet Mala

    2016-07-01

    Full Text Available Cultural Hungarian-Albanian relations during the Middle Ages are characterized by a relatively poor intensity. Actually, relations between these two countries are more intense in the political field and especially through the partnership between Gjergj Kastrioti Skanderbeg and John Hunyadi. Regarding the origin, the Hungarian culture identity is rather distinct from the Albanian one. Lack of cultural contacts, among others, was conditioned also by the fact that these relations were held under war circumstances and their primary aim was the common defense from Ottoman attacks. Actually, the Albanian medieval culture remained a Mediterranean culture with elements of Byzantine influence in the continental and southern areas. Meanwhile, Hungary belonged to Central Europe, which, even though far away from Mediterranean cultural mainstream, sought to be influenced by this culture, namely by the Renaissance that emanated exactly in the Mediterranean region. It was Matthias Corvinus effort, regarding the cultural influence of the Mediterranean and Renaissance in Hungary but also the fact that Hungary possessed some of the most important towns of the Adriatic coast and particularly Ragusa. This city was the center where cultural relations between Albanian and Hungary started and became intensified in the religious, intellectual and human field.

  18. Actual legal questions and problems of the free access to information, especially in the environmental protection; Aktuelle Rechtsfragen und Probleme des freien Informationszugangs, insbesondere im Umweltschutz

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Meinhard (ed.)

    2010-07-01

    Within the 26th Trier colloquium on the law governing environmental protection and technology at 5th to 7th September, 2010 in Trier (Federal Republic of Germany), the following lectures were held: (1) The environmental law in the light of federalism and Europeanization (Hans-Juergen Papier); (2) Information rights in the EU (Astrid Epiney); (3) Environmental policy by freedom of information (Friedrich Schoch); (4) The legal framework for the opening of the access to information as well as the appearance of accessible information under special consideration of the environmental information Directive 2003/4/EG and its implementation in the German Law (Joern Axel Kaemmerer); (5) The utilization of electronic media: REACh data bases, publication of authorizing procedures in the Internet and geo data mediation such as google maps (Indra Spiecker); (6) Protection position of companies in the right of access to information. The protection of business secrets and commercial confidentialities as well as application dossiers in the European and German law (Matthias Rossi); (7) Limited protection of business secrets and commercial confidentialities as a part of genetic engineering legal approval procedures (Hartwig Stiebler); (8) The NRW pipeline cadastre (Alexander Schink); (9) Legal protection by European and national courts under consideration of the European Ombudsman in his function in securing the access of information (Sabine Schlacke).

  19. 2nd Rochester Conference on Superconductivity in D- and F- Band Metals

    CERN Document Server

    Superconductivity in d- and f- band metals

    1976-01-01

    The occurrence of superconductivity among the d- and f-band metals remains one of the unsolved problems of physics. The first Rochester conference on this subject in October 1971 brought together approximately 100 experimentalists and theorists, and that conference was considered successful; the published proceedings well-represented the current research at that time and has served as a "handbook" to many. In the four and one half years since the first conference, impressive progress has been made in many areas (although Berndt Matthias would be one of the first to point out that raising the m"aximum transition temperature by a significant amount was not one of them). For a variety of reasons, I decided that it was time for a Second Rochester Conference on Superconductivity in d- and f-Band Metals and it was held on April 30 and May 1, 1976. It would appear that this conference was even more successful judging from the quality of the talks and various comments made to me. I believe that this was due...

  20. Was ist so Berlin? Eine kritische Rezension aktueller Linien und Fragestellungen der Stadtforschung in der deutschen Hauptstadt

    Directory of Open Access Journals (Sweden)

    Samuel Merrill

    2014-10-01

    Full Text Available Ende 2012 hat das Zitty Magazin des Tagesspiegels seine Werbekampagne „Das ist so Berlin“ gestartet. Seither sind kleine rot-weiße Aufkleber mit dieser Aussage überall in der Stadt aufgetaucht, auf Mülleimern, U-Bahn-Schildern und Bushaltestellen. Zum Teil als Reaktion auf diese Kampagne, fragt diese kritische, bilinguale Rezension Was ist so Berlin? um die aktuellen Linien und Fragestellungen der Stadtforschung in Berlin zu diskutieren. Dazu werden die Berlin-Sitzungen zweier internationaler Tagungen des Jahres 2013 rezensiert, die Sitzungen der Jahreskonferenz der Association of American Geographers (Los Angeles 9-13 April und es Jahrestreffen des Research Committee 21 (Berlin 29-31, sowie der Sammelband – The Berlin Reader: A Compendium on Urban Change and Activism (Transcript, 2013, herausgegeben von Matthias Bernt, Britta Grell und Andrej Holm. Im Anschluss betont die Rezension die Notwendigkeit die Vorstellungen zu Berlin und Berlins exceptionalism, die in der Stadtforschung entwickelt werden, fortlaufend so zu beleuchten, dass eine pluralistische Rhetorik, die Position und Verantwortung von Forscher_innen und wissenschaftliche Forschungslücken, berücksichtigt werden.

  1. Classification of lead white pigments using synchrotron radiation micro X-ray diffraction

    International Nuclear Information System (INIS)

    Welcomme, E.; Walter, P.; Menu, M.; Bleuet, P.; Hodeau, J.L.; Dooryhee, E.; Martinetto, P.

    2007-01-01

    Lead white pigment was used and synthesised for cosmetic and artistic purposes since the antiquity. Ancient texts describe the various recipes, and preparation processes as well as locations of production. In this study, we describe the results achieved on several paint samples taken from Matthias Gruenewald's works. Gruenewald, who was active between 1503 and 1524, was a major painter at the beginning of the German Renaissance. Thanks to X-ray diffraction analysis using synchrotron radiation, it is possible to associate the composition of the paint samples with the masters ancient recipes. Different approaches were used, in reflection and transmission modes, directly on minute samples or on paint cross-sections embedded in resin. Characterisation of lead white pigments reveals variations in terms of composition, graininess and proportion of mineral phases. The present work enlightens the presence of lead white as differentiable main composition groups, which could be specific of a period, a know-how or a geographical origin. In this way, we aim at understanding the choices and the trading of pigments used to realise paintings during northern European Renaissance. (orig.)

  2. Strengthening Routine Data Systems to Track the HIV Epidemic and Guide the Response in Sub-Saharan Africa.

    Science.gov (United States)

    Rice, Brian; Boulle, Andrew; Baral, Stefan; Egger, Matthias; Mee, Paul; Fearon, Elizabeth; Reniers, Georges; Todd, Jim; Schwarcz, Sandra; Weir, Sharon; Rutherford, George; Hargreaves, James

    2018-04-03

    The global HIV response has entered a new phase with the recommendation of treating all persons living with HIV with antiretroviral therapy, and with the goals of reducing new infections and AIDS-related deaths to fewer than 500,000 by 2020. This new phase has intensive data requirements that will need to utilize routine data collected through service delivery platforms to monitor progress toward these goals. With a focus on sub-Saharan African, we present the following priorities to improve the demand, supply, and use of routine HIV data: (1) strengthening patient-level HIV data systems that support continuity of clinical care and document sentinel events; (2) leveraging data from HIV testing programs; (3) using targeting data collection in communities and among clients; and (4) building capacity and promoting a culture of HIV data quality assessment and use. When fully leveraged, routine data can efficiently provide timely information at a local level to inform action, as well as provide information at scale with wide geographic coverage to strengthen estimation efforts. ©Brian Rice, Andrew Boulle, Stefan Baral, Matthias Egger, Paul Mee, Elizabeth Fearon, Georges Reniers, Jim Todd, Sandra Schwarcz, Sharon Weir, George Rutherford, James Hargreaves. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 03.04.2018.

  3. Conference on storage in the service of energy transition

    International Nuclear Information System (INIS)

    Leuthold, Matthias; Marchal, David; Sitte, Ralf; Kairies, Kai-Philipp; Guerrier, Pierre; Netzel, Niklas; Radvanyi, Etienne; Lenck, Thorsten

    2016-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on energy storage supporting the energy transition in France and in Germany. In the framework of this French-German exchange of experience, about 140 participants met together to debate about the answer of future storage technologies to the electric power system needs and to the optimum integration of renewable energies at different levels of the power transmission and distribution grid. This document brings together the available presentations (slides) made during this event: 1 - Storage Technologies, Status and Perspectives (Matthias Leuthold); 2 - Which electricity storage needs for 2030, 2050 in France? (David Marchal); 3 - Storage in context of the German 'Energiewende' (Ralf Sitte); 4 - Battery Storage for residential PV Systems: Grid relieving effects (Kai-Philipp Kairies); 5 - Battery Storage for residential PV Systems: Technologies and Market Trends (Kai-Philipp Kairies); 6 - Pumped hydro-stations to ensure a decentralized and flexible storage to integrate the best way RES in the electric system (Pierre Guerrier); 7 - RRKW Feldheim - Primary Frequency Control in a wind feed-in grid (Niklas Netzel); 8 - Smoothing an intermittent generation: interest of generation forecast and storage global management (Etienne Radvanyi); 9 - Power-to-gas after 2030 - A cost-benefit analysis (Thorsten Lenck)

  4. Recovery of a 10-year-old girl from methicillin-resistant Staphylococcus aureus sepsis in response to low-dose ceftaroline treatment

    Directory of Open Access Journals (Sweden)

    Borgmann S

    2016-05-01

    Full Text Available Stefan Borgmann,1 Beate Rieß,1 Thomas von Wernitz-Keibel,2 Matthias Bühler,3 Franziska Layer,4 Birgit Strommenger4 1Department of Infectious Diseases and Infection Control, 2Department of Anaesthesiology and Intensive Care Medicine, 3Department of Trauma Surgery, Klinikum Ingolstadt, Ingolstadt, 4National Reference Centre for Staphylococci and Enterococci, Division Nosocomial Pathogens and Antibiotic Resistances, Department for Infectious Diseases, Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany Abstract: A 9-year-old girl was severely injured in a car accident in Afghanistan, in which both her lower legs were badly damaged. She was treated at the Hospital of Ingolstadt (Klinikum Ingolstadt after she had undergone initial surgery at an Indian hospital. Various bacterial species were isolated from multiple wounds, and methicillin-resistant Staphylococcus aureus (MRSA was one among them. After the amputation of her lower legs, she developed MRSA sepsis, which was successfully treated with a relatively low dosage of ceftaroline (Zinforo®/Teflaro®; 2×9 mg/kg/d, although the bacterial isolate’s minimal inhibitory concentration (1.5–4 mg/L suggested a decreased susceptibility. In summary, ceftaroline was highly efficient and well tolerated by the patient suffering from MRSA sepsis. Keywords: side effects, susceptibility, ceftaroline, minimal inhibitory concentration, therapy 

  5. Cine-Club

    CERN Multimedia

    Cine-Club

    2011-01-01

    Thursday 24 May 2012 at 20:00 CERN Council Chamber Nowhere in Africa / Nirgendwo in Afrika By: Caroline Link (Germany, 2001) 141 min Based on the novel by Stephanie Zweig With: Juliane Köhler, Merab Ninidze, Matthias Habich A love story spanning two continents, Nowhere in Africa is the extraordinary true tale of a Jewish family who flees the Nazi regime in 1938 for a remote farm in Kenya.  Abandoning their once-comfortable existence in Germany, Walter Redlich, his wife Jettel and their 5-year-old daughter Regina, each deal with the harsh realities of their new life in different ways. Attorney Walter is resigned to working the farm as a caretaker; pampered Jettel resists adjustment at every turn; while the shy yet curious Regina immediately embraces the country – learning the local language and customs, and finding a friend in Owuor the farm’s cook.  As the war rages on the other side of the world, the trio’s relationships to their str...

  6. A history of plant biotechnology: from the Cell Theory of Schleiden and Schwann to biotech crops.

    Science.gov (United States)

    Vasil, Indra K

    2008-09-01

    Plant biotechnology is founded on the principles of cellular totipotency and genetic transformation, which can be traced back to the Cell Theory of Matthias Jakob Schleiden and Theodor Schwann, and the discovery of genetic transformation in bacteria by Frederick Griffith, respectively. On the 25th anniversary of the genetic transformation of plants, this review provides a historical account of the evolution of the theoretical concepts and experimental strategies that led to the production and commercialization of biotech (transformed or transgenic) plants expressing many useful genes, and emphasizes the beneficial effects of plant biotechnology on food security, human health, the environment, and conservation of biodiversity. In so doing, it celebrates and pays tribute to the contributions of scores of scientists who laid the foundation of modern plant biotechnology by their bold and unconventional thinking and experimentation. It highlights also the many important lessons to be learnt from the fascinating history of plant biotechnology, the significance of history in science teaching and research, and warns against the danger of the growing trends of ignoring history and historical illiteracy.

  7. Conference on wind energy and grid integration

    International Nuclear Information System (INIS)

    Laffaille, Didier; Boemer, Jens; Fraisse, Jean-Luc; Mignon, Herve; Gonot, Jean-Pierre; Rohrig, Kurt; Lange, Matthias; Bagusche, Daniel; Wagner, Stefan; Schiel, Johannes

    2008-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on the grid integration of wind farms. In the framework of this French-German exchange of experience, more than 80 participants exchanged views on the evolutions of tariffs and licensing procedures, and on grid capacity improvements and production forecasts. This document brings together the available presentations (slides) made during this event: 1 - The necessary evolution of billing and procedures for wind turbines connection to the grid in France (Didier Laffaille); 2 - Improvement of wind turbines integration to the grid in the framework of the EEG 2009 law (Jens Boemer); 3 - Decentralized power generation on the French power grids - 15, 20 kV and low voltage (Jean-Luc Fraisse); 4 - GOTTESWIND? Solution for the future: towards a grid evolution (Herve Mignon); 5 - Production forecasts in Germany - State-of-the-art and challenges for the grid exploitation (Kurt Rohrig); 6 - High-voltage lines capacity evaluation in meteorological situations with high wind energy production (Matthias Lange); 7 - The IPES project for the integration of wind energy production in the exploitation of the French power system (Jean-Pierre Gonot); 8 - Experience feedback from a wind turbine manufacturer in France and in Germany (Daniel Bagusche); 9 - Solutions for grid security improvement and capacity enhancement: cooperation between grid and power plant operators (Stefan Wagner); 10 - Open questions on wind energy integration to French and German grids (Johannes Schiel)

  8. „Vater einer großen Nachkommenschaft von Forschungsreisenden ...“ Ehrungen Alexander von Humboldts im Jahre 1869

    Directory of Open Access Journals (Sweden)

    Ilse Jahn

    2004-04-01

    Full Text Available Article in German, Abstracts in English and GermanIn 1869 the “Naturwissenschaftlicher Verein” was founded in Magdeburg (Saxony Anhalt. That was the time when the scientific world celebrated Alexander von Humboldt’s 100th birthday. In this context, Humboldt’s achievements were remembered during the founding ceremony of that society. The paper which was read in September 2003 on a meeting of this organisation, focuses on three famous naturalists who celebrated Humboldt because they owed him much help in their own professional careers. The botanist Matthias Jacob Schleiden gave a memorial speech in 1869 in Dresden. The physiologist and pioneer of electro-biology Emil du Bois-Reymond honoured his mentor A. v. Humboldt on the occasion of the dedication of the statues of Wilhelm and Alexander in 1883 in Berlin. Charles Darwin expressed his gratitude to Humboldt by sending him in 1839 the report of his travels and received an interesting reply. These three scholars represented a new epoch in the development of the natural sciences. The paper includes a recently re-discovered letter from Humboldt to Schleiden, dated April 13, 1842.

  9. Clinical preference for factors in treatment of geriatric depression

    Directory of Open Access Journals (Sweden)

    Riepe MW

    2014-12-01

    Full Text Available Matthias W Riepe Mental Health and Geriatric Psychiatry, Psychiatry II, Ulm University, Ulm, Germany Abstract: Little is known about symptom preferences of clinical psychiatrists in the treatment of geriatric depression and preferences for avoiding adverse drug effects. Participants (board-certified psychiatrists were recruited prior to a lecture on geriatric depression during a continuing education program. An analytic hierarchy process was performed and participants were asked for pairwise comparison of criteria guiding them in appraising therapeutic efficacy, and in avoiding toxicity and adverse events. Of the 61 participants from the continuing education program, 42 (69% returned their data sheet. Avoidance of cardiotoxicity was regarded as more important than avoidance of hepatotoxicity or hematotoxicity. Concerning adverse events, highest preference was given to avoidance of falls and drug interactions, followed by avoidance of sedation, weight change, and impairment of sexual function. The most important preferences for appraisal of therapeutic efficacy were suicidality over ability to concentrate and sleep. Clinical psychiatrists have a hierarchy of preferences for treatment goals and avoidance of adverse events and toxicity. This raises the question for future research whether these preferences cause differences in prescription patterns in clinical practice even though a multitude of antidepressants are similarly effective when judged with instruments used in clinical trials. Keywords: depressive disorder, symptoms, analytic hierarchy process, toxicity, adverse events, symptoms

  10. 15. dialogue on waste management MV. Current developments in waste and resources economics. Proceedings; 15. Dialog Abfallwirtschaft MV. Aktuelle Entwicklungen in der Abfall und Ressourcenwirtschaft. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Nelles, Michael (ed.)

    2012-07-01

    Within the 15th dialogue on waste management MV at the University of Rostock (Rostock, Federal Republic of Germany) at 13th June, 2012, the following lectures were held: (1) 20 Years GAA - 20 years of successful work (Hartwig Roessler); (2) Acquisition and evaluation of waste management data in Mecklenburg-Western Pommerania - A basis for planning for strategies according to Cycle and Waste Management Act KrWG (Helmut Kietzmann); (3) Demographic change in Mecklenburg-Western Pommerania - Implications for the waste management (Matthias Leuchter); (4) The HPWM project (Jan Marquardt); (5) Consequences of the modified legal and regulatory situation for the operation of refuse-fuelled power stations (Kurt Wengenroth); (6) Foodstuffs in the waste - Analysis and mitigation proposals (Jakob Barabosz); (7) Disposal of electric and electronic equipment as well as manufacturer responsibility (Vera Susanne Rotter); (8) Advanced waste management concepts in developing countries - foundable? Realizable? Sustainable? (Wolfgang Pfaff-Simoneit); (9) Further development of the mechanical-biological waste treatment (Stephan Schuett); (10) Airjet-pipecleaner - the automatic cleaning facility for ventilation nozzles (Armin Seidel); (11) Exploitation of reusable materials from bottom ash (Dirk Bludau); (12) Is the thermal treatment suitable for the utilization of glass-fibre reinforced plastics wastes? (Karl-Heinz Plepla); (13) Recyclability of bioplastics(An-Sophie Kitzler); (14) Development of process-oriented quality inspections for the near private collection of refuse and recyclable material (Nico Schulte).

  11. Arbitration in environmental matters. An interdisciplinary introduction; Studienbrief Umweltmediation. Eine interdisziplinaere Einfuehrung

    Energy Technology Data Exchange (ETDEWEB)

    Claus, F; Fietkau, H J; Fuchs, G [and others

    2000-07-01

    This textbook provides a comprehensive and systematic introduction to the process of arbitration in environmental matters, both for self-studies and for participants in the seminars on which it is based. The interdisciplinary readership is reflected in the interdisciplinary group of authors. The publication can be used as a training programme. [German] Mit Vorliegen dieses Studienbriefs wird erstmals eine Moeglichkeit geboten, sich umfassend und systematisch, im Eigenstudium oder im Rahmen des dazugehoerigen Seminarprogramms, mit dem Verfahren der Umweltmediation vertraut zu machen. Der Vielfalt der angesprochenen Zielgruppen (Politik, Verwaltung, Wirtschaft, Rechtswesen usw.) wurde in der interdisziplinaeren Zusammensetzung des Autorenkreises Rechnung getragen. Das Layout wurde so gestaltet, dass es die inhaltliche Orientierung erleichert. Zusaetzlich kann der Studienbrief auch als Bauelement fuer eine umfassendere Wissensaneignung dienen: Erstens ist es moeglich, sich ueber das oben genannte Ausbildungsprogramm fuer Praktiker zum Mediator fortzubilden. Zweitens besteht die Chance, das erworbene Wissen durch einen Lehrgang zur Agenda-Moderation des Wissenschaftsladen Bonn e.V. um weitere konsens- und handlungsorientierte Verfahren zu erweitern. Informationen koennen ueber den Foerderverein Umweltmediation e.V., Matthias-Gruenewald-Str. 1-3, 53175 Bonn, Tel. 0228/3 72 99 27, eingeholt werden. (orig.)

  12. Energy technology of tomorrow. Strategies and concepts. Conference contributions; Energietechnik von morgen. Strategien und Konzepte. Konferenzbeitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Within the meeting 'Energy technology of tomorrow - Strategies and concepts' at 12th June, 2007 in Nuremberg (Federal Republic of Germany) the following lectures were held: (1) Cluster energy technology (Klaus Hassmann); (2) Dimension of future energy supply - prognoses/strategies/concepts (Ludger Mohrbach); (3) Future technologies for a CO{sub 2} reduced energy supply (Helmut Tschaffon); (4) Energy research - New specific targets and results (Hartmut Spliethoff); (5) Technological progress for future power plants at RWE (Frank Schwending); (6) Future potential of the generation of syngas with different energy sources (Sebastian Muschelknautz); (7) Innovations in plant engineering - on the way to a CO{sub 2} free power plant (Tobias Jockenhoevel); (8) Solar thermal power plants - status and prospects (Robert Piltz-Paal); (9) Perspectives of the generation of liquid hydrocarbons using nuclear energy (Kurt Kugeler); (10) Application of the MPG gasification technology in the refining of Canadian tar sands (Matthias Mueller-Hagedorn); (11) Perspectives for a sustainable supply with energy carriers (Ulrich Balfanz).

  13. The Rise of Basic Research at tha Bell Labs: Young Turks and Younger Turks

    Science.gov (United States)

    Anderson, Philip

    2004-03-01

    ABSTRACT Even before World War II, a certain amount of fundamental physics research came out of the Bell Labs. Already in the 20's, before the Labs were five years old, the discoveries of electron diffraction by Davisson and Germer, and of thermal noise by Johnson and Nyquist, had come as byproducts of wide-ranging technological studies. By the late '30's, there was a small group of broadly-trained scientists who formed a nucleus around which the "young turks" in management --J B Fisk, M J Kelly, W Shockley, perhaps others--formed the postwar physical research department, comprising at first perhaps 50 people with a mandate to do exploratory but "relevant" research. This talk will diiscuss how some of the generation of postwar hires, with the cooperation of enlightened managers like W O Baker and A H White, further tested and enlarged their freedom to do basic, curiosity-driven research in an academic atmosphere. I call this group, consisting of individuals like B T Matthias, G H Wannier, R G Shulman, P A Wolff, myself , and a number of others, the "younger Turks".

  14. Conference on the role of biomethane in the energy transition in France and in Germany

    International Nuclear Information System (INIS)

    Reizine, Stanislas; Edel, Matthias; Theobald, Olivier; Pierre, Frederic; Mestrel, Jean Marc; Grope, Johan; Scholwin, Frank; Eberlein, Jens; Renard, Suzanne; Trommler, Marcus; Demeusy, Tatiana; Chapelat, Nicolas; Lefebvre, Mathieu

    2015-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on the role of biomethane in the energy transition in France and in Germany. In the framework of this French-German exchange of experience, about 110 participants exchanged views on the status of the legal framework and of the development of biomethane industry in the French and German energy transitions. This document brings together the available presentations (slides) made during this event: 1 - Biomethane injection in France - elaboration and implementation of the price structure (Stanislas Reizine); 2 - Biomethane framework conditions in Germany 3 - German Road-map for Biomethane (Matthias Edel); 4 - A vision for biomethane in France in 2030 - purified biogas injection in the natural gas network (Olivier Theobald); 5 - Biomethane produced by the Strasbourg-la Wantzenau waste water plant and injected into the GDS natural gas network (Frederic Pierre); 6 - Biomethane fuel in Lille city: 1995-2015 100% clean and renewable energy in transportation (Jean Marc Mestrel); 7 - Biomethane from organic waste and its utilisation (Johan Grope); 8 - Marketing of Biomethane to end consumers (Jens Eberlein); 9 - Developing new approaches to promote injection into the grid (Suzanne Renard); 10 - Demand driven power supply from Bioenergy - a balancing option for power distribution networks (Marcus Trommler); 11 - Flexible biogas production and its integration to power and gas grids (Tatiana Demeusy); 12 - A partnership for the development of Agricultural methanization plants around a single injection point (Nicolas Chapelat); 13 - Keynotes: biomethane development paths to favour (Mathieu Lefebvre)

  15. A new biogeographically disjunct giant gecko (Gehyra: Gekkonidae: Reptilia) from the East Melanesian Islands

    Science.gov (United States)

    Oliver, Paul M.; Clegg, Jonathan R.; Fisher, Robert N.; Richards, Stephen J.; Taylor, Peter N.; Jocque, Merlijn M. T.

    2016-01-01

    The East Melanesian Islands have been a focal area for research into island biogeography and community ecology. However, previously undescribed and biogeographically significant new species endemic to this region continue to be discovered. Here we describe a phylogenetically distinct (~20% divergence at the mitochondrial ND2 gene) and biogeographically disjunct new species of gecko in the genus Gehyra, from the Admiralty and St Matthias Islands. Gehyra rohan sp. nov. can be distinguished from all congeners by the combination of its very large size, ring of bright orange scales around the eye, moderate degree of lateral folding on the limbs and body, and aspects of head, body and tail scalation. Molecular data indicate mid to late Miocene divergence of the new species from nearest relatives occurring nearly 2000 kilometres away in Vanuatu and Fiji. Large Gehyra have not been recorded on the intervening large islands of the Bismark Archipelago (New Britain and New Ireland) and the Solomon Islands, suggesting this dispersal pre-dated the current configuration of these islands, extinction in intervening regions, or potentially elements of both. Conversely, low genetic divergence between disjunct samples on Manus and Mussau implies recent overseas dispersal via either natural or anthropogenic means.

  16. Classification of lead white pigments using synchrotron radiation micro X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Welcomme, E.; Walter, P.; Menu, M. [Centre de Recherche et de Restauration des Musees de France - CNRS UMR 171, Paris (France); Bleuet, P. [European Synchrotron Radiation Facility, BP 220, Grenoble Cedex (France); Hodeau, J.L.; Dooryhee, E.; Martinetto, P. [Institut Neel CNRS-UPR 503-1, 25, Av. des Martyrs, BP 166, Grenoble Cedex 9 (France)

    2007-12-15

    Lead white pigment was used and synthesised for cosmetic and artistic purposes since the antiquity. Ancient texts describe the various recipes, and preparation processes as well as locations of production. In this study, we describe the results achieved on several paint samples taken from Matthias Gruenewald's works. Gruenewald, who was active between 1503 and 1524, was a major painter at the beginning of the German Renaissance. Thanks to X-ray diffraction analysis using synchrotron radiation, it is possible to associate the composition of the paint samples with the masters ancient recipes. Different approaches were used, in reflection and transmission modes, directly on minute samples or on paint cross-sections embedded in resin. Characterisation of lead white pigments reveals variations in terms of composition, graininess and proportion of mineral phases. The present work enlightens the presence of lead white as differentiable main composition groups, which could be specific of a period, a know-how or a geographical origin. In this way, we aim at understanding the choices and the trading of pigments used to realise paintings during northern European Renaissance. (orig.)

  17. Climate change and ecological restructuring of industrial society; Klimawandel und oekologischer Umbau der Industriegesellschaft

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Within the European Conference at 22nd/23rd September, 2010 at the Thuringian state chancellery Erfurt (Federal Republic of Germany) the following lectures were held: (1) The climatic change and the global development (Dirk Messner); (2) Reconstruction of the industrial society: How can Vorarlberg achieve the aim of the EU up to 2020 (Bertram Schedler); (3) The part of renewable energy sources in Germany: Establishment of an infrastructure with low CO{sub 2} emissions in the energy supply and facility management (Ursula Heinen); (4) Securing the energy supply under the aegis of the shortages of petroleum, natural gas and coal: The role of renewable energy resources and solar energy in the solar state of Thuringia (Matthias Machnig); (5) ''Desert Energy'' for Europe: From the vision to reality (Thorsten Marquardt); (6) Solar primary industry under the Bitterfelder Bogen from the view of the modern ''solar site with future'' (Hilmar Tiefel); (7) CO{sub 2} reduction, energy efficiency and renewable energies: European research politics for a better energy supply (Reinhard Wecker); (8) Panel discussion on the improvement of the efficiency / price reduction and compensation for electricity fed into the grid: How do owners of companies and buildings motivate to more commitment for solar energy? (Harry Lehmann, Ami Elazari, Dieter D. Genske).

  18. Dimensões comunicacionais no conceito de escultura social de Joseph Beuys como possibilidade de tradução criativa.

    Directory of Open Access Journals (Sweden)

    Magda Salete Vicini

    Full Text Available O presente artigo é resultado de pesquisa de doutorado em Comunicação e Semiótica, realizada na PUC-SP, sobre o conceito de Escultura Social na obra de Joseph Beuys, com recorte em pesquisadores como Matthias Bunge e Caroline Tisdall, bem como a influência dos filósofos românticos Schiller, Goethe, Hegel e de Novalis na construção deste conceito na obra de Rudolf Steiner. O contexto da arte é abordado através de críticos de arte que analisam o trabalho artístico de Beuys, cujas características comunicacionais são apresentadas em relação a Humberto Maturana e Francisco Varella e à crítica da comunicação. Finalmente, o artigo aborda a possibilidade de tradução criativa (Walter Benjamin, Georg Steiner e Haroldo de Campos deste conceito de Joseph Beuys.

  19. Gold Medal for Finnish Health in All Policies Book

    Directory of Open Access Journals (Sweden)

    Ray Lewis

    2014-02-01

    Full Text Available This article is a review of the book “Health in All Policies: Seizing opportunities, implementing policies” edited by Kimmo Leppo, Eeva Ollila, Sebastián Peña, Matthias Wismar, and Sarah Cook. This book (printed and online publication was published by the Finnish Ministry of Social Affairs and Health, Finland in 2013 (1. The book is freely available at http://www.euro.who.int/__data/assets/pdf_file/0007/188809/Health-in-All-Policies-final.pdf. The main features, structure, and highlighted contents of the book are briefly sketched out in this review. The book promotes understanding of a Health in All Policies (HiAP approach, the history, and the scientific evidence of effectiveness available to apply the HiAP concept in order to overcome challenges faced by policy-makers. HiAP is a relatively novel approach which arises from the traditional idea that health is not only medicine (2. The book offers lessons to policy-makers and managers on how to apply the HiAP approach. It further highlights the health sector’s role in developing healthy public policies. In addition, the book provides examples of structures to foster collaboration, coherence, and participation among stakeholders from different government portfolios and responsibilities. The book further provides invaluable insights for politicians, researchers, and civil society advocates.

  20. Avaliação e recondicionamento pulmonar ex vivo Ex vivo lung evaluation and reconditioning

    Directory of Open Access Journals (Sweden)

    Paulo Manuel Pêgo-Fernandes

    2010-12-01

    Full Text Available OBJETIVO: Apenas 15% dos pulmões doados são aproveitados para transplante. Um novo método de Perfusão Pulmonar Ex Vivo (PPEV foi desenvolvido e pode ser usado para avaliação e recondicionamento de pulmões "marginais" e rejeitados para o transplante. Esse trabalho relata nossa experiência com a avaliação funcional da PPEV. MÉTODOS: Foram estudados pulmões de 12 doadores considerados inapropriados para transplante pulmonar. Após a captação, os pulmões são perfundidos ex vivo com Steen Solution, uma solução de composição eletrolítica extracelular com alta pressão coloidosmótica. Um oxigenador de membrana ligado ao circuito recebe uma mistura gasosa (nitrogênio e dióxido de carbono e "desoxigena" o perfusato, mantendo uma concentração de gases semelhante a do sangue venoso. Os pulmões são gradualmente aquecidos, perfundidos e ventilados. A avaliação dos órgãos é feita por gasometrias e medidas como a resistência vascular pulmonar (RVP e complacência pulmonar (CP. RESULTADOS: A PaO2 (FiO2 100% passou de um valor médio de 193,3 mmHg no doador para 495,3 mmHg durante a PPEV. Após uma hora de PPEV, a RVP média era de 737,3 dinas/seg/ cm5 e a CP era de 42,2 ml/cmH2O. CONCLUSÕES: O modelo de avaliação pulmonar ex vivo pode melhorar a capacidade de oxigenação de pulmões "marginais" inicialmente rejeitados para transplante. Isso denota um grande potencial do método para aumentar a disponibilidade de pulmões para transplante e, possivelmente, reduzir o tempo de espera nas filas.OBJECTIVE: Only about 15% of the potential candidates for lung donation are considered suitable for transplantation. A new method for ex vivo lung perfusion (EVLP has been developed and can be used for evaluation and reconditioning of "marginal" and unacceptable lungs. This is a report of functional evaluation experience with ex vivo perfusion of twelve donor lungs deemed unacceptable in São Paulo, Brazil. METHODS: After harvesting, the

  1. ”Hvad angår det mig som jurist?” - refleksion over jurastuderendes møde med nye fagligheder

    Directory of Open Access Journals (Sweden)

    Louise Victoria Johansen

    2016-10-01

    Full Text Available Jurastuderende på danske universiteter bliver i stigende grad introduceret for tværfaglig undervisning, som giver dem mulighed for at kunne reflektere over deres fag udefra. Mange jurastuderende møder dog disse kurser med en stærk monofaglig forståelse opnået gennem deres hidtidige jurastudium. Deres læreproces i løbet af kurserne er derfor afhængig af undervisers håndtering af denne allerede etablerede jurafaglige identitet. Med udgangspunkt i Steen Becks sammentænkning af læringsteoretikerne Jean Piaget og Lev Vygotsky argumenterer denne artikel for, at tværfaglig undervisning på jurastudiet indebærer mere end blot at lære ny teori og nye metoder; den forudsætter også aflæring af de faglige forståelser, som særligt skygger for at kunne inddrage andre discipliner end den juridiske. Artiklen beskriver denne balance mellem aflæring og nylæring gennem en refleksion over min undervisning på et obligatorisk bachelorfag samt et kursusfag på kandidatuddannelsen ved Det Juridiske Fakultet, Københavns Universitet. Disse kurser har forskellige betingelser i forhold til den undervisningstid, der kan allokeres til de studerendes arbejde med nye metodiske tilgange. Ud over disse organisatoriske forskelle har det dog også vist sig, at undervisers anvendelse af de første undervisningsgange kan være afgørende for de studerendes læreproces, samt at metakommunikation om aktiviteterne bør være meget tydelig. Law students at Danish universities are increasingly being introduced to interdisciplinary teaching that allows them to reflect on their subjects from an outside perspective. Many law students, however, approach these courses with a strong mono professional understanding obtained through their law studies. Consequently, their learning process during these courses is dependent on the teacher's handling of this already established legal professional identity. Based on Steen Beck's fusion of educational theorists Jean Piaget and

  2. Calculation of additional costs in 2010 - for the demolition of the Swedish nuclear power plants and disposal of residues; Beraekning av merkostnader 2010 - foer rivning av de svenska kaernkraftsverken och omhaendertagande av restprodukter

    Energy Technology Data Exchange (ETDEWEB)

    Brewitz, Erica; Schoultz, Christian; Wetzel, Carina

    2010-09-15

    This report describes the SSM's calculation of additional costs for fee proposal for 2012-2014. The calculation is made pursuant to the Financing Act and includes all additional costs until the residue from the Swedish nuclear power plants is disposed of. According to current calculations, this should be done in 2069. Estimates of such a long time means a great deal of uncertainty and SSM uses, like SKB, the successive calculation method to estimate an expected value and tax association uncertainty. As a starting point for analysis, the SSM has made estimates of the future costs broken down into paragraphs in paragraph 2 Financing Act. The estimates were made after discussions within the organization and representatives of relevant external organizations. Assuming a total annual cost per worker of 1.24 million gave these estimates a total cost of over three billion. It should be emphasized that this sum is only a starting point for analysis and applies in particular circumstances. These circumstances critically reviewed the analysis and the reasonableness of assessments made by a analysis group. The analysis took place for 2.5 days in spring 2010. The analysis group consisted of 17 people including nine from the SSM. Lores Borg and Steen Lichtenberg were moderators. Via a brainstorming process, the analysis group presented a number of uncertainties and made a three-part assessment of their impact on the overall results (minimum, most likely and maximum). The result of the analysis: average in the 2010 monetary value was assessed to 4.24 billion Swedish crowns with a standard deviation of 920 million Swedish crowns. These values are undiscounted

  3. Low starting dosage of infliximab with possible escalating dosage in psoriatic arthritis gives the same treatment results as standard dosage of adalimumab or etanercept: results from the nationwide Icelandic ICEBIO registry

    Directory of Open Access Journals (Sweden)

    Gudbjornsson B

    2018-05-01

    Full Text Available Bjorn Gudbjornsson,1,2 Arni Jon Geirsson,3,4 Niels Steen Krogh5 1Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland; 2Faculty of Medicine, University of Iceland, Reykjavik, Iceland; 3Department of Rheumatology, University Hospital, Reykjavik, Iceland; 4Laeknasetrid - Medical Clinic, University of Iceland, Reykjavik, Iceland; 5Zitelab Aps, Copenhagen, Denmark Objective: To explore differences in response to a low dosage regimen of infliximab with an escalating dosage in comparison to a standard dosage of etanercept and adalimumab in patients with psoriatic arthritis (PsA. Methods: Biologically naïve PsA patients who were beginning anti-TNF-α therapy were selected from the ICEBIO registry. Demographics and clinical differences were compared in four treatment groups: infliximab <4 mg/kg; infliximab >4 mg/kg; etanercept or adalimumab at baseline and on follow-up (6 and 12 months, last visit. The Kruskal–Wallis rank sum test was used for comparison of the groups and the Wilcoxon test to compare the two infliximab dosage regimens. Results: One hundred and eighty-five patients (61% female were identified; 84 patients received infliximab, 66 etanercept, and 35 adalimumab. A total of 19% of the patients treated with infliximab escalated their dosage ≥4 mg/kg. No significant differences were observed at baseline in respect to visual analog scale (VAS pain, VAS fatigue, Health Assessment Questionnaire, C-reactive protein (CRP, numbers of swollen or tender joints, or Disease Activity Score (DAS 28-CRP values. A similar treatment response was observed in all four treatment groups on follow-up. Conclusion: In respect to treatment effects, a low dosage of infliximab with possible escalating dosage is acceptable for the majority of PsA patients who are in need of biological treatment. Keywords: psoriatic arthritis, outcome, biological treatment, routine care, clinical nationwide registry

  4. Changes of EEG and CT findings in patients with dementia of Alzheimer type

    Energy Technology Data Exchange (ETDEWEB)

    Shinohara, Masao; Higashidani, Yoshiaki; Kawakatsu, Shinobu; Totsuka, Shirou [Yamagata Univ. (Japan). Faculty of Medicine; Ariumi, Kiyohiko; Kinoshita, Osami

    1992-01-01

    Computed tomography (CT) was performed in 39 patients with dementia of Alzheimer type (DAT) and 16 normal subjects. Three CT parameters, including the Sylvian fissure/brain area (SBR) ratio, the lateral ventricle/brain area (VBR) ratio, and the ratio of the maximum diameter of the third ventricle to the intracranial diameter (III V), were examined in terms of the severity of DAT and electroencephalograms (EEG). All of the CT parameters were significantly increased in the group of patients with severe DAT. They were also correlated with intelligence test scores obtained by the Hasegawa Dementia Scale and the Gottfries-Brane-Steen Scale. The intelligence test scores became worse with increasing cerebral atrophy. There was a strong correlation between the III V ratio and both VBR and SBR ratios; however, there was no correlation between VBR and SBR ratios. SBR ratio was well correlated with {delta}-, {theta}-, and {beta} 1-percentage power fraction (PPF) in the frontal, temporal, parietal, and occipital lobes on the left side, and slightly correlated with {delta}- and {alpha}-PPF in the frontal lobe alone on the right side. For all of the four lobes, VBR was correlated with {delta}-PPF on the left side and {delta}- and {beta} 1-PPF on the right side. III V ratio was correlated with {delta}-PPF in the bilateral four lobes and {alpha} 1-PPF and {alpha} 2-PPF in the four lobes on the left side and in the three lobes on the right side. The aforementioned correlation between CT and PPF suggests the strong involvement of subcortical disturbance in the abnormality on EEG in patients with DAT. (N.K.).

  5. Changes of EEG and CT findings in patients with dementia of Alzheimer type

    International Nuclear Information System (INIS)

    Shinohara, Masao; Higashidani, Yoshiaki; Kawakatsu, Shinobu; Totsuka, Shirou; Ariumi, Kiyohiko; Kinoshita, Osami.

    1992-01-01

    Computed tomography (CT) was performed in 39 patients with dementia of Alzheimer type (DAT) and 16 normal subjects. Three CT parameters, including the Sylvian fissure/brain area (SBR) ratio, the lateral ventricle/brain area (VBR) ratio, and the ratio of the maximum diameter of the third ventricle to the intracranial diameter (III V), were examined in terms of the severity of DAT and electroencephalograms (EEG). All of the CT parameters were significantly increased in the group of patients with severe DAT. They were also correlated with intelligence test scores obtained by the Hasegawa Dementia Scale and the Gottfries-Brane-Steen Scale. The intelligence test scores became worse with increasing cerebral atrophy. There was a strong correlation between the III V ratio and both VBR and SBR ratios; however, there was no correlation between VBR and SBR ratios. SBR ratio was well correlated with δ-, θ-, and β 1-percentage power fraction (PPF) in the frontal, temporal, parietal, and occipital lobes on the left side, and slightly correlated with δ- and α-PPF in the frontal lobe alone on the right side. For all of the four lobes, VBR was correlated with δ-PPF on the left side and δ- and β 1-PPF on the right side. III V ratio was correlated with δ-PPF in the bilateral four lobes and α 1-PPF and α 2-PPF in the four lobes on the left side and in the three lobes on the right side. The aforementioned correlation between CT and PPF suggests the strong involvement of subcortical disturbance in the abnormality on EEG in patients with DAT. (N.K.)

  6. Effect of aromatherapy on patients with Alzheimer's disease.

    Science.gov (United States)

    Jimbo, Daiki; Kimura, Yuki; Taniguchi, Miyako; Inoue, Masashi; Urakami, Katsuya

    2009-12-01

    Recently, the importance of non-pharmacological therapies for dementia has come to the fore. In the present study, we examined the curative effects of aromatherapy in dementia in 28 elderly people, 17 of whom had Alzheimer's disease (AD). After a control period of 28 days, aromatherapy was performed over the following 28 days, with a wash out period of another 28 days. Aromatherapy consisted of the use of rosemary and lemon essential oils in the morning, and lavender and orange in the evening. To determine the effects of aromatherapy, patients were evaluated using the Japanese version of the Gottfries, Brane, Steen scale (GBSS-J), Functional Assessment Staging of Alzheimer's disease (FAST), a revised version of Hasegawa's Dementia Scale (HDS-R), and the Touch Panel-type Dementia Assessment Scale (TDAS) four times: before the control period, after the control period, after aromatherapy, and after the washout period. All patients showed significant improvement in personal orientation related to cognitive function on both the GBSS-J and TDAS after therapy. In particular, patients with AD showed significant improvement in total TDAS scores. Result of routine laboratory tests showed no significant changes, suggesting that there were no side-effects associated with the use of aromatherapy. Results from Zarit's score showed no significant changes, suggesting that caregivers had no effect on the improved patient scores seen in the other tests. In conclusion, we found aromatherapy an efficacious non-pharmacological therapy for dementia. Aromatherapy may have some potential for improving cognitive function, especially in AD patients.

  7. Is the track of the Yellowstone hotspot driven by a deep mantle plume? -- Review of volcanism, faulting, and uplift in light of new data

    Science.gov (United States)

    Pierce, Kenneth L.; Morgan, Lisa A.

    2009-01-01

    Geophysical imaging of a tilted mantle plume extending at least 500 km beneath the Yellowstone caldera provides compelling support for a plume origin of the entire Yellowstone hotspot track back to its inception at 17 Ma with eruptions of flood basalts and rhyolite. The widespread volcanism, combined with a large volume of buoyant asthenosphere, supports a plume head as an initial phase. Estimates of the diameter of the plume head suggest it completely spanned the upper mantle and was fed from sources beneath the transition zone, We consider a mantle–plume depth to at least 1,000 km to best explain the large scale of features associated with the hotspot track. The Columbia River–Steens flood basalts form a northward-migrating succession consistent with the outward spreading of a plume head beneath the lithosphere. The northern part of the inferred plume head spread (pancaked) upward beneath Mesozoic oceanic crust to produce flood basalts, whereas basalt melt from the southern part intercepted and melted Paleozoic and older crust to produce rhyolite from 17 to 14 Ma. The plume head overlapped the craton margin as defined by strontium isotopes; westward motion of the North American plate has likely "scraped off" the head from the plume tail. Flood basalt chemistries are explained by delamination of the lithosphere where the plume head intersected this cratonic margin. Before reaching the lithosphere, the rising plume head apparently intercepted the east-dipping Juan de Fuca slab and was deflected ~ 250 km to the west; the plume head eventually broke through the slab, leaving an abruptly truncated slab. Westward deflection of the plume head can explain the anomalously rapid hotspot movement of 62 km/m.y. from 17 to 10 Ma, compared to the rate of ~ 25 km/m.y. from 10 to 2 Ma.

  8. Beware Cold Agglutinins in Organ Donors! Ex Vivo Lung Perfusion From an Uncontrolled Donation After Circulatory-Determination-of-Death Donor With a Cold Agglutinin: A Case Report.

    Science.gov (United States)

    Venkataraman, A; Blackwell, J W; Funkhouser, W K; Birchard, K R; Beamer, S E; Simmons, W T; Randell, S H; Egan, T M

    2017-09-01

    We began to recover lungs from uncontrolled donation after circulatory determination of death to assess for transplant suitability by means of ex vivo lung perfusion (EVLP) and computerized tomographic (CT) scan. Our first case had a cold agglutinin with an interesting outcome. A 60-year-old man collapsed at home and was pronounced dead by Emergency Medical Services personnel. Next-of-kin consented to lung retrieval, and the decedent was ventilated and transported. Lungs were flushed with cold Perfadex, removed, and stored cold. The lungs did not flush well. Medical history revealed a recent hemolytic anemia and a known cold agglutinin. Warm nonventilated ischemia time was 51 minutes. O 2 -ventilated ischemia time was 141 minutes. Total cold ischemia time was 6.5 hours. At cannulation for EVLP, established clots were retrieved from both pulmonary arteries. At initiation of EVLP with Steen solution, tiny red aggregates were observed initially. With warming, the aggregates disappeared and the perfusate became red. After 1 hour, EVLP was stopped because of florid pulmonary edema. The lungs were cooled to 20°C; tiny red aggregates formed again in the perfusate. Ex vivo CT scan showed areas of pulmonary edema and a pyramidal right middle lobe opacity. Dissection showed multiple pulmonary emboli-the likely cause of death. However, histology showed agglutinated red blood cells in the microvasculature in pre- and post-EVLP biopsies, which may have contributed to inadequate parenchymal preservation. Organ donors with cold agglutinins may not be suitable owing to the impact of hypothermic preservation. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. A nodalization study of steam separator in real time simulation

    International Nuclear Information System (INIS)

    Horugshyang, Lein; Luh, R.T.J.; Zen-Yow, Wang

    1999-01-01

    The motive of this paper is to investigate the influence of steam separator nodalization on reactor thermohydraulics in terms of stability and level response. Three different nodalizations of steam separator are studied by using THEATRE and REMARK Code in a BWR simulator. The first nodalization is the traditional one with two nodes for steam separator. In this nodalization, the steam separation is modeled in the outer node, i.e., upper downcomer. Separated steam enters the Steen dome node and the liquid goes to the feedwater node. The second nodalization is similar to the first one with the steam separation modeled in the inner node. There is one additional junction connecting steam dome node and the inner node. The liquid fallback junction connects the inner node and feedwater node. The third nodalization is a combination of the former two with an integrated node for steam separator. Boundary conditions in this study are provided by a simplified feedwater and main steam driver. For comparison purpose, three tests including full power steady state initialisation, recirculation pumps runback and reactor scram are conducted. Major parameters such as reactor pressure, reactor level, void fractions, neutronic power and junction flows are recorded for analysis. Test results clearly show that the first nodalization is stable for steady state initialisation. However it has too responsive level performance in core flow reduction transients. The second nodalization is the closest representation of real plant structure, but not the performance. Test results show that an instability occurs in the separator region for both steady state initialisation and transients. This instability is caused by an unbalanced momentum in the dual loop configuration. The magnitude of the oscillation reduces as the power decreases. No superiority to the other nodalizations is shown in the test results. The third nodalization shows both stability and responsiveness in the tests. (author)

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1971-04-01

    Full Text Available - A.H.N. Verwey, A.J. Bernet Kempers, Borobudur: Mysteriegebeuren in steen, Verval en restauratie, Oudjavaans volksleven. Servire, Wassenaar 1970. 224 blz., 280 afb. - Graham W. Irwin, Anthony Reid, The contest for North Sumatra. Atjeh, the Netherlands and Britain 1858-1898. Kuala Lumpur and London: University of Malaya Press and Oxford University Press, 1969. 333 p., 8 plates, maps. - John Bastin, Fernand Mendes Pinto, The voyages and adventures of Fernand Mendez Pinto: Translated into English by H. Cogan 1635. Dawsons of Pall Mall. The Colonial History Series, General Editor, D.H. Simpson. London, 1969. Pages xiv + 318. - R. Roolvink, Yahya Ismail, Satu kajian mengenai karya2 Ahmad Talu. Dewan Bahasa dan Pustaka, Kuala Lumpur, 1970. XIV + 82 pp. - Harry Aveling, Umar Junus, Perkembangan puisi Melayu moden. Dewan Bahasa dan Pustaka, Kuala Lumpur 1970. XIV + 161 pp. - A.F. Ros, Clifford Geertz, Islam observed: Religious development in Morocco and Indonesia. Yale University Press, New Haven and London 1968. XII en 136 blz. - Go Gien Tjwan, Joseph-John Nevadomsky, The Chinese in Southeast Asia. A selected and annotated bibliography of publications in Western languages 1960-1970. Occasional Paper No. 6 of the Center for South and Southeast Asia Studies, University of California, Berkeley, California, 1970, 119 p., Alice Li (eds. - F.G. Bailey, S. Arasaratnam, Indians in Malaysia and Singapore. Oxford University Press for Institute of Race Relations, London 1970. 241 pp. - A.F. Marks, G.J. Kruijer, Cuba; Voorbeeld en uitdaging. Polak en Van Gennep, Amsterdam, 1968. 146 bladzijden; met foto’s. - ,

  11. Metaphor in the ESP engineering context

    Directory of Open Access Journals (Sweden)

    Ana Roldán-Riejos

    2013-04-01

    Full Text Available The explicit use of metaphor in the EFL classroom has been documented to enhance the communicative skills of learners (Cameron & Low, 1999; Cortazzi & Jin, 1999; Low, 1999; Littlemore & Low, 2006. ESP learners with a technical background, however, are not usually trained on the presence of metaphor in their knowledge field, or on its use. The aim of this paper is to analyze the unprompted use of metaphor in the verbal responses given by a group of Spanish civil engineering undergraduates when depicting visuals related to their area of expertise. The responses of the students were obtained from a questionnaire completed in the classroom which was later crosschecked with the answers given by a group of professional civil engineers. This was done to compare the occurrence of metaphor as a descriptive verbalizer in the academic and the professional contexts. The results confirm the use of general metaphor in both groups, and the use of field-specific metaphor particularly in the professional engineers (in order to avoid confusion with the engineer students group, which appears to suggest the evolving character of metaphor in the civil engineering discourse community. We conclude by highlighting the dynamicity of metaphor in the civil engineering context. From a pedagogic viewpoint, it would be advisable to concentrate on metaphor as a learning feature by considering three main dimensions: conceptual, linguistic and visual. This could be carried out by offering students corpora-driven examples of metaphor visibility in the different civil engineering genres, addressing non-verbal elements, such as sketches, drawings, designs and pictures where metaphor may be used. The theoretical framework for this study draws from conceptual metaphor theory and conceptual integration theory combined with a multimodal approach to metaphor (Fauconnier & Turner, 2002; Deignan, 2005; Steen, 2007; Fauconnier & Turner, 2008, Forceville, 2010; Kress, 2010.

  12. Biogas in the agriculture. State of the art. Proceedings; Biogas in der Landwirtschaft. Stand und Perspektiven. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Within the meeting of the Association for Technology and Structures in Agriculture (Darmstadt, Federal Republic of Germany) and the Agency for Renewable Resources (Guelzow, Federal Republic of Germany) between 15th and 16th September, 2009, in Weimar the following lectures were held: (1) Results of the actual biogas measurement II (Peter Weiland); (2) Agitators in biogas plants - Technology with central significance (Kay Rostalski); (3) How much energy is needed by a biogas fermenter? (Ludwig Heinloth); (4) The fermentation concept of Rueckert NatUrgas GmbH (Claus Rueckert, Dominique Pfeufer); (5) Experiences from the construction for the practice of the company MT-Energie GmbH (Bodo Drescher); (6) Fermenter/technology concept of Schmack Biogas AG (Thomas Moeeslinger); (7) Transport of biomass - How much does the logistics of Guelle and Co. cost? (Thore Toews); (8) Which factors determine the efficiency of biogas plants? (Gerd Reinhold); (9) Microbial diversity in biogas reactors in the fermentation of renewable raw materials (Michael Klocke et al.); (10) What do additives and ingredients contribute to the optimisation of the production of biogas? (Udo Hoelker); (11) Process optimisation - An interaction between technology and microbiology (Andreas Gronauer et al.); (12) Emissions at the production of biogas - an analysis if the environmental relevance (Joachim Clemens et al.); (13) Support systems for energy plants - Consequences to soil and environment (Matthias Willms et al.); (14) How ecological is biogas? (Sven Gaertner); (15) Biogas plant - Analysis of construction and operation from licensing view (Hans-Walter Schneichel); (16) Biogas plants - Analysis of construction and operation from contractual legal view (Florian Valentin); (17) Biogasplants - Analysis of construction and operation from remuneration legal view (Helmut Loibl); (18) Process and costs of treatment of residues of fermentation (Sebastian Wulf, Helmut Doehler); (19) How do residues of

  13. Cross-species functionality of pararetroviral elements driving ribosome shunting.

    Directory of Open Access Journals (Sweden)

    Mikhail M Pooggin

    Full Text Available BACKGROUND: Cauliflower mosaic virus (CaMV and Rice tungro bacilliform virus (RTBV belong to distinct genera of pararetroviruses infecting dicot and monocot plants, respectively. In both viruses, polycistronic translation of pregenomic (pg RNA is initiated by shunting ribosomes that bypass a large region of the pgRNA leader with several short (sORFs and a stable stem-loop structure. The shunt requires translation of a 5'-proximal sORF terminating near the stem. In CaMV, mutations knocking out this sORF nearly abolish shunting and virus viability. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that two distant regions of the CaMV leader that form a minimal shunt configuration comprising the sORF, a bottom part of the stem, and a shunt landing sequence can be replaced by heterologous sequences that form a structurally similar configuration in RTBV without any dramatic effect on shunt-mediated translation and CaMV infectivity. The CaMV-RTBV chimeric leader sequence was largely stable over five viral passages in turnip plants: a few alterations that did eventually occur in the virus progenies are indicative of fine tuning of the chimeric sequence during adaptation to a new host. CONCLUSIONS/SIGNIFICANCE: Our findings demonstrate cross-species functionality of pararetroviral cis-elements driving ribosome shunting and evolutionary conservation of the shunt mechanism. We are grateful to Matthias Müller and Sandra Pauli for technical assistance. This work was initiated at Friedrich Miescher Institute (Basel, Switzerland. We thank Prof. Thomas Boller for hosting the group at the Institute of Botany.

  14. 2012 Aspen Winter Conference New Paradigms for Low-Dimensional Electronic Materials, February 5-10, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Joel; Rabe, Karin; Nayak, Chetan; Troyer, Matthias

    2012-05-01

    Aspen Center for Physics Project Summary DOE Budget Period: 10/1/2011 to 9/30/2012 Contract # DE-SC0007479 New Paradigms for Low-Dimensional Electronic Materials The 2012 Aspen Winter Conference on Condensed Matter Physics was held at the Aspen Center for Physics from February 5 to 10, 2012. Seventy-four participants from seven countries, and several universities and national labs attended the workshop titled, New Paradigms for Low-Dimensional Electronic Materials. There were 34 formal talks, and a number of informal discussions held during the week. Talks covered a variety of topics related to DOE BES priorities, including, for example, advanced photon techniques (Hasan, Abbamonte, Orenstein, Shen, Ghosh) and predictive theoretical modeling of materials properties (Rappe, Pickett, Balents, Zhang, Vanderbilt); the full conference schedule is provided with this report. The week's events included a public lecture (Quantum Matters given by Chetan Nayak from Microsoft Research) and attended by 234 members of the public, and a physics caf© geared for high schoolers that is a discussion with physicists conducted by Kathryn Moler (Stanford University) and Andrew M. Rappe (University of Pennsylvania) and attended by 67 locals and visitors. While there were no published proceedings, some of the talks are posted online and can be Googled. The workshop was organized by Joel Moore (University of California Berkeley), Chetan Nayak (Microsoft Research), Karin Rabe (Rutgers University), and Matthias Troyer (ETH Zurich). Two organizers who did not attend the conference were Gabriel Aeppli (University College London & London Centre for Nanotechnology) and Andrea Cavalleri (Oxford University & Max Planck Hamburg).

  15. Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

    Directory of Open Access Journals (Sweden)

    Gerlach N

    2016-09-01

    Full Text Available Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke University, Witten, 2Evonik Nutrition & Care GmbH, Essen, Germany *These authors contributed equally to this work Abstract: Sphingolipids are well known to promote keratinocyte differentiation and to induce ceramide production. In addition, they show anti-inflammatory and antimicrobial activities. Thus, the aim of this study is to investigate the potential effect of sphinganine on prolonging the hair anagen rate and improving the overall hair quality and scalp health. The inhibitory potential of sphinganine toward 5-α-reductase was studied using an in vitro assay. The stimulation of the antimicrobial peptide HBD2 by sphinganine was measured by real-time polymerase chain reaction and immunostaining. Sphinganine bioavailability was studied ex vivo using a pig skin model. A placebo-controlled, double-blind study was designed to evaluate the efficacy of sphinganine on hair loss and hair/scalp quality in vivo. In vitro results showed that sphinganine is a potent inhibitor of 5-α-reductase type I that prevents the conversion of testosterone to dihydrotestosterone, a key factor of androgenetic male baldness. In vivo results demonstrated efficacy in reducing non-illness-related hair loss among males. In terms of expert rating, all hair quality and scalp parameters improved after application of sphinganine. Improved scalp health might be linked to the observed increase of the antimicrobial peptide HBD2. Thus, sphinganine is well suited as a topical alternative for the improvement of scalp health and hair quality and anti-hair loss application. Keywords: sphinganine, 5-α-reductase inhibition, HBD2, hair loss, anagen rate, TrichoScan®

  16. Is freezing in the vaccine cold chain an ongoing issue? A literature review.

    Science.gov (United States)

    Hanson, Celina M; George, Anupa M; Sawadogo, Adama; Schreiber, Benjamin

    2017-04-19

    Vaccine exposure to temperatures below recommended ranges in the cold chain may decrease vaccine potency of freeze-sensitive vaccines leading to a loss of vaccine investments and potentially places children at risk of contracting vaccine preventable illnesses. This literature review is an update to one previously published in 2007 (Matthias et al., 2007), analyzing the prevalence of vaccine exposure to temperatures below recommendations throughout various segments of the cold chain. Overall, 45 studies included in this review assess temperature monitoring, of which 29 specifically assess 'too cold' temperatures. The storage segments alone were evaluated in 41 articles, 15 articles examined the transport segment and 4 studied outreach sessions. The sample size of the studies varied, ranging from one to 103 shipments and from three to 440 storage units. Among reviewed articles, the percentage of vaccine exposure to temperatures below recommended ranges during storage was 33% in wealthier countries and 37.1% in lower income countries. Vaccine exposure to temperatures below recommended ranges occurred during shipments in 38% of studies from higher income countries and 19.3% in lower income countries. This review highlights continuing issues of vaccine exposure to temperatures below recommended ranges during various segments of the cold chain. Studies monitoring the number of events vaccines are exposed to 'too cold' temperatures as well as the duration of these events are needed. Many reviewed studies emphasize the lack of knowledge of health workers regarding freeze damage of vaccines and how this has an effect on temperature monitoring. It is important to address this issue by educating vaccinators and cold chain staff to improve temperature maintenance and supply chain management, which will facilitate the distribution of potent vaccines to children. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Changes in body weight after 24 weeks of vildagliptin therapy as a function of fasting glucose levels in patients with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Blüher M

    2014-11-01

    Full Text Available Matthias Blüher,1 Anja Schweizer,2 Giovanni Bader,2 James E Foley3 1Department of Medicine, University of Leipzig, Leipzig, Germany; 2Novartis Pharma AG, Basel, Switzerland; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA Background: In order to test the hypothesis that the degree of weight change with the dipeptidyl peptidase-4 inhibitor vildagliptin is dependent on the level of glycemic control at baseline, the weight changes from pooled monotherapy studies after 24 weeks of therapy with vildagliptin were assessed versus the fasting plasma glucose (FPG levels at baseline. Methods: Data were pooled from eight clinical monotherapy trials including 2,340 previously drug-naïve patients with type 2 diabetes mellitus who received vildagliptin monotherapy (50 mg once daily [n=359] or 50 mg twice daily [n=1,981]. The trials were all randomized, double-blind, controlled clinical trials with a prespecified week 24 study visit. Results: Linear regression analysis of weight change after 24 weeks relative to baseline FPG showed an intercept of −2.259 kg (95% confidence interval −2.86, −1.66; P<0.0001 and a positive slope of 0.1552 kg (95% confidence interval 0.10–0.21; P<0.0001. Neutral caloric balance (no weight change was observed at a FPG of 14.6 mmol/L (263 mg/dL. Baseline FPG values below and above this threshold were associated with weight loss and weight gain, respectively. For instance, from this analysis, a baseline FPG of 8 mmol/L (144 mg/dL predicts a weight loss of 1 kg. Conclusion: The present analysis showed that treatment with vildagliptin results in a negative caloric balance when glucose levels are below the renal threshold at baseline. Keywords: dipeptidyl peptidase-4 inhibitor, glucagon-like peptide-1, renal threshold, sodium-glucose cotransporter-2 inhibitor, hyperglycemia

  18. Neuer Atheismus: New Atheism in Germany

    Directory of Open Access Journals (Sweden)

    Thomas Zenk

    2012-06-01

    Full Text Available Matthias Knutzen (born 1646 – died after 1674 was the first author we know of who self-identified as an atheist (Schröder 2010: 8. Before this, the term had solely been used pejoratively to label others. While Knutzen is almost completely forgotten now, authors such as Ludwig Feuerbach, Karl Marx, Friedrich Nietzsche, or Sigmund Freud are better remembered and might even be considered classic writers in the history of the atheist criticism of religion. Whatever may be said about the influence of any one of these authors, there is no doubt that Germany looks back on a notable history in this field. About a decade ago, Germany’s capital Berlin was even dubbed ‘the world capital of atheism’ by the American sociologist Peter L. Berger (2001: 195.Given this situation, I am bewildered by the expression ‘New Atheism’. Yet, undoubtedly, the term has become a catchphrase that is commonly used in the public discourse of several countries. The most prominent authors to be labelled ‘New Atheists’ are Richard Dawkins (The God Delusion, 2006, Daniel Dennett (Breaking the Spell: Religion as a Natural Phenomenon, 2006, Sam Harris (The End of Faith: Religion, Terror, and the Future of Reason, 2004, and Letter to a Christian Nation, 2006, and Christopher Hitchens (God Is Not Great: How Religion Poisons Every­thing, 2007. These authors and their books – all of them international bestsellers – have been intensely discussed around the world, including in Germany. In this paper, I intend to illuminate some of the characteristics and remarkable traits of the German discourse on the ‘New Atheism’. Here we can distinguish between two phases. The German media initially characterised ‘New Atheism’ as a rather peculiarly American phenomenon. However, it soon came to be understood to be a part of German culture as well.

  19. Quantum dot systems: artificial atoms with tunable properties

    International Nuclear Information System (INIS)

    Weis, J.

    2005-01-01

    Full text: Quantum dots - also called zero-dimensional electron systems or artificial atoms - are physical objects where the constituent electrons are confined in a small spatial region, leading to discrete eigenvalues for the energies of the confined electrons. Large quantum dots offer a dense energy spectrum comparable to that of metallic grains, whereas small quantum dots more closely resemble atoms in their electronic properties. Quantum dots can be linked to leads by tunnel barriers, hence permitting electrical transport measurements: Coulomb blockade and single-electron charging effects are observed due to the repulsive electron electron interaction on the quantum dot site. Usually fabricated by conventional semiconductor growth and processing technology, the advantage is that both simple and also more complex quantum dot systems can be designed to purpose, acting as model systems with in-situ tunable parameters such as the number of confined electrons in the quantum dot and the strength of the tunnel coupling to the leads, electrostatically controlled by the applied voltages to gate electrodes. With increasing the tunnel coupling to the leads, the virtual occupation of the quantum dot from the leads becomes more and more important -- the simple description of electrical transport by single-electron tunneling events breaks down. The basic physics is described by the Kondo physics based on the Anderson impurity model. A system consisting of strongly electrostatically coupled quantum dots with separate leads to each quantum dot represent another realization of the Anderson impurity model. Experiments to verify the analogy are presented. The experimental data embedded within this tutorial have been obtained with Alexander Huebel, Matthias Keller, Joerg Schmid, David Quirion, Armin Welker, Ulf Wilhelm, and Klaus von Klitzing. (author)

  20. The ability of natural tolerance to be applied to allogeneic tissue: determinants and limits

    Directory of Open Access Journals (Sweden)

    Razavy Haide

    2007-04-01

    Full Text Available Abstract Background Transplant rejection has been considered to occur primarily because donor antigens are not present during the development of the recipient's immune system to induce tolerance. Thus, transplantation prior to recipient immune system development (pre-immunocompetence transplants should induce natural tolerance to the donor. Surprisingly, tolerance was often not the outcome in such 'natural tolerance models'. We explored the ability of natural tolerance to prevent immune responses to alloantigens, and the reasons for the disparate outcomes of pre-immunocompetence transplants. Results We found that internal transplants mismatched for a single minor-H antigen and 'healed-in' before immune system development were not ignored but instead induced natural tolerance. In contrast, multiple minor-H or MHC mismatched transplants did not consistently induce natural tolerance unless they carried chimerism generating passenger lymphocytes. To determine whether the systemic nature of passenger lymphocytes was required for their tolerizing capacity, we generated a model of localized vs. systemic donor lymphocytes. We identified the peritoneal cavity as a site that protects allogeneic lymphocytes from killing by NK cells, and found that systemic chimerism, but not chimerism restricted to the peritoneum, was capable of generating natural tolerance. Conclusion These data provide an explanation for the variable results with pre-immunocompetence transplants and suggest that natural tolerance to transplants is governed by the systemic vs. localized nature of donor antigen, the site of transplantation, and the antigenic disparity. Furthermore, in the absence of systemic lymphocyte chimerism the capacity to establish natural tolerance to allogeneic tissue appears strikingly limited. Reviewers This article was reviewed by Matthias von Herrath, Irun Cohen, and Wei-Ping Min (nominated by David Scott.

  1. Comparison of clinical outcomes in PRK with a standard and aspherical optimized profile: a full case analysis of 100 eyes with 1-year follow-up

    Directory of Open Access Journals (Sweden)

    Dausch D

    2014-11-01

    Full Text Available Dieter Dausch,1,2 Burglinde Dausch,2 Matthias Wottke,3 Georg Sluyterman van Langeweyde31Chung-Ang University, Seoul, South Korea; 2Augen-Laser-Klinik Nürnberg, Nuremberg, Germany; 3Carl Zeiss Meditec AG, Jena, Germany Purpose: One hundred eyes from 55 adult patients with myopia were retrospectively studied to determine the comparative safety, efficacy, and predictability of aberration smart ablation (ASA and a new advanced ablation algorithm (Triple-A using the MEL® 80 excimer laser.Methods: Fifty myopic eyes with a manifest refraction spherical equivalent (MRSE between -1.0 diopters (D and -9.75 D were consecutively treated with photorefractive keratectomy ASA, and 50 myopic eyes with an MRSE between -1.38 D and -11.0 D with photorefractive keratectomy Triple-A. Uncorrected distance visual acuity, MRSE, the absolute value of the cylinder, corrected distance visual acuity, and postoperative complications at 1 month, 3 months, 6 months, and 12 months (1 year were descriptively analyzed and compared at 1 year.Results: After 12 months, the MRSE variance was statistically significantly better in patients triaged to receive Triple-A compared with patients receiving ASA (ASA, ±0.7 D; Triple-A, ±0.15 D; P<0.001. Furthermore, no patient in the Triple-A group had any cylinder postoperatively. Patients in the Triple-A treatment arm achieved a superior result. No statistically significant difference in the two treatment arms was noted for the analysis of the mean MRSE at 12 months (P=0.78.Conclusion: Triple-A was more effective than standard aspherical surgical intervention in a number of treatment outcome parameters (eg, MRSE, astigmatism, efficacy index. The two surgical procedures were equivalent in terms of safety. Keywords: aberration smart ablation (ASA, manifest refraction spherical equivalent, Triple-A advanced ablation algorithm, uncorrected distance visual acuity, corrected distance visual acuity, excimer laser, PRK, ablation profile

  2. Bystander signaling via oxidative metabolism

    Directory of Open Access Journals (Sweden)

    Sawal HA

    2017-08-01

    Full Text Available Humaira Aziz Sawal,1 Kashif Asghar,2 Matthias Bureik,3 Nasir Jalal4 1Healthcare Biotechnology Department, Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, 2Basic Sciences Research, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan; 3Health Science Platform, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China; 4Health Science Platform, Department of Molecular and Cellular Pharmacology, Tianjin University, Tianjin, China Abstract: The radiation-induced bystander effect (RIBE is the initiation of biological end points in cells (bystander cells that are not directly traversed by an incident-radiation track, but are in close proximity to cells that are receiving the radiation. RIBE has been indicted of causing DNA damage via oxidative stress, besides causing direct damage, inducing tumorigenesis, producing micronuclei, and causing apoptosis. RIBE is regulated by signaling proteins that are either endogenous or secreted by cells as a means of communication between cells, and can activate intracellular or intercellular oxidative metabolism that can further trigger signaling pathways of inflammation. Bystander signals can pass through gap junctions in attached cell lines, while the suspended cell lines transmit these signals via hormones and soluble proteins. This review provides the background information on how reactive oxygen species (ROS act as bystander signals. Although ROS have a very short half-life and have a nanometer-scale sphere of influence, the wide variety of ROS produced via various sources can exert a cumulative effect, not only in forming DNA adducts but also setting up signaling pathways of inflammation, apoptosis, cell-cycle arrest, aging, and even tumorigenesis. This review outlines the sources of the bystander effect linked to ROS in a cell, and provides methods of investigation for researchers who would like to

  3. Preparing for a Career in Industrial Physics

    Science.gov (United States)

    Meisner, Gregory

    My career in physics has been extremely rewarding. My career path, however, was not what I imagined it would be when I started college. I thought I would be a math major and eventually a university math professor. A big challenge of my college and graduate school experience, aside from actually learning physics, was to find out what I was most passionate about and then to pursue that endeavor wherever it led. The graduate school part of my career path wound its way into experimental condensed matter physics, but I still expected that I would remain in academia. Along the way, I learned a lot from many people, worked hard to accomplish good results, and availed myself of unexpected opportunities for professional development and career advancement. One piece of advice that resonated with me was to always try to be learning something new, and I did manage to do that throughout my career: in graduate school and as a post doc I studied low temperature experimental physics and superconductivity, whereas my areas of research as an industrial physicist at GM R&D were permanent magnets, then hydrogen storage materials for fuel cell vehicle applications, and finally thermoelectric materials and devices for waste exhaust gas heat recovery. The best piece of advice, which has served me well along my career path and my life path in general, was in the remarks astronaut Katherine Sullivan gave at my PhD graduation ceremony at UCSD in 1982. Her advice was captured in the word ``quality''. Specifically, always strive for the highest quality in everything you do. Another impactful word, which was a favorite of my thesis advisor, Bernd Matthias, is ``serendipity''. Specifically, you need to know how to recognize and capitalize on unexpected or unusual occurrences - they may be the best stepping stones you will have along your career path. My presentation will discuss a few specifics of how I prepared myself for a career in industrial physics.

  4. Reconciling top-down and bottom-up estimates of CO2 fluxes to understand increased seasonal exchange in Northern ecosystems

    Science.gov (United States)

    Bastos, A.; Ciais, P.; Zhu, D.; Maignan, F.; Wang, X.; Chevallier, F.; Ballantyne, A.

    2017-12-01

    Continuous atmospheric CO2 monitoring data indicate enhanced seasonal exchange in the high-latitudes in the Northern Hemisphere (above 40oN), mainly attributed to terrestrial ecosystems. Whether this enhancement is mostly explained by increased vegetation growth due to CO2 fertilization and warming, or by changes in land-use and land-management practices is still an unsettled question (e.g. Forkel et al. (2016) and Zeng et al. (2013)). Previous studies have shown that models present variable performance in capturing trends in CO2 amplitude at CO2 monitoring sites, and that Earth System Models present large spread in their estimates of such trends. Here we integrate data of atmospheric CO2 exchange in terrestrial ecosystems by a set of atmospheric CO2 inversions and a range of land-surface models to evaluate the ability of models to reproduce changes in CO2 seasonal exchange within the observation uncertainty. We then analyze the factors that explain the model spread to understand if the trend in seasonal CO2 amplitude may indeed be a useful metric to constrain future changes in terrestrial photosynthesis (Wenzel et al., 2016). We then compare model simulations with satellite and other observation-based datasets of vegetation productivity, biomass stocks and land-cover change to test the contribution of natural (CO2 fertilization, climate) and human (land-use change) factors to the increasing trend in seasonal CO2 amplitude. Forkel, Matthias, et al. "Enhanced seasonal CO2 exchange caused by amplified plant productivity in northern ecosystems." Science 351.6274 (2016): 696-699. Wenzel, Sabrina, et al. "Projected land photosynthesis constrained by changes in the seasonal cycle of atmospheric CO2." Nature 538, no. 7626 (2016): 499-501.Zeng, Ning, et al. "Agricultural Green Revolution as a driver of increasing atmospheric CO2 seasonal amplitude." Nature 515.7527 (2014): 394.

  5. International Materials Research Meeting in the Greater Region: “Current Trends in the Characterisation of Materials and Surface Modification”

    Science.gov (United States)

    2017-10-01

    Preface Dear ladies and gentlemen, On 6th and 7th of April 2017 took place the “International Materials Research Meeting in the Greater Region” at the Saarland University, Saarbrücken, Germany. This meeting corresponded to the 9th EEIGM International Conference on Advanced Materials Research and it was intended as a meeting place for researchers of the Greater Region as well as their partners of the different cooperation activities, like the EEIGM program, the ‘Erasmus Mundus’ Advanced Materials Science and Engineering Master program (AMASE), the ‘Erasmus Mundus’ Doctoral Program in Materials Science and Engineering (DocMASE) and the CREATe-Network. On this meeting, 72 participants from 15 countries and 24 institutions discussed and exchanged ideas on the latest trends in the characterization of materials and surface modifications. Different aspects of the material research of metals, ceramics, polymers and biomaterials were presented. As a conclusion of the meeting, the new astronaut of the European Space Agency Dr. Matthias Maurer, who is an alumni of the Saarland University and the EEIGM, held an exciting presentation about his activities. Following the publication of selected papers of the 2009 meeting in Volume 5 and 2012 meeting in Volume 31 of this journal, it is a great pleasure to present this selection of 9 articles to the readers of the IOP Conference Series: Materials Science and Engineering. The editors are thankful to all of the reviewers for reviewing the papers. Special praise is also given to the sponsors of the conference: European Commission within the program Erasmus Mundus (AMASE and DocMASE), Erasmus+ (AMASE), and Horizon2020 (CREATe-Network, Grant agreement No 644013): the DAAD (Alumni Program), and the German-French University (PhD-Track). List of Author signatures, Conference topics, Organization, Conference impressions and list of the participants are available in this PDF.

  6. Theory summary

    International Nuclear Information System (INIS)

    Quinn, H.R.

    1992-01-01

    This talk briefly summarizes the theoretical contributions presented on the previous day of the meeting. Readers are recommended to turn to the contributions on those talks for further details. My job in this talk is to review all the theoretical contributions presented to this meeting. Paul Avery has reviewed the more experimentally oriented contributions to the Physics and Simulation session. Let me begin by stressing some points from my own introductory talk. The major focus of a B-factory must be more than just observing CP violation in one or more channels. The task before us is to test the predictions of the Standard Model, which means that it is important not just to define the Unitarity triangle, but in fact to measure enough separate parameters that the triangle is overconstrained. The consistency or otherwise of the various determinations of the triangle will then provide a check on the consistency of Standard Model predictions. To overconstrain the triangle we must either measure all three angles, or, if we can only measure two angles, then we must in addition measure two sides. The side opposite the angle α is effectively determined by V cb while that opposite the angle β is fixed by V ub . Thus we need good measurements of both V cb and V ub . The quantity V cb can be well measured. Matthias Neubert showed, in his talk, how predictions from heavy quark symmetry can be used cleanly to extract it from B → D * eν decays. The quantity V ub is more difficult. Heavy quark symmetries can again be used, here to relate semileptonic decays of the B or B * (to π or ρ and eν) to similar decays of the D and D *

  7. Birch pollen influence the severity of atopic eczema – prospective clinical cohort pilot study and ex vivo penetration study

    Directory of Open Access Journals (Sweden)

    Fölster-Holst R

    2015-10-01

    Full Text Available Regina Fölster-Holst,1 Jagoda Galecka,1 Sigo Weißmantel,1 Ute Dickschat,2 Frank Rippke,3 Kerstin Bohnsack,3 Thomas Werfel,4 Katja Wichmann,4 Matthias Buchner,1 Thomas Schwarz,1 Annika Vogt,5 Jürgen Lademann,5 Martina C Meinke5 1Department of Dermatology, Venerology and Allergy, University of Kiel, 2Wörth, 3Beiersdorf AG, Hamburg, 4Department of Dermatology, Venerology and Allergy, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, 5Department of Dermatology, Venerology and Allergology, Charité – Universitätsmedizin Berlin, Berlin, Germany Abstract: There is little clinical evidence for a correlation between the severity of atopic eczema (AE and pollen exposition. To obtain more data, we performed a clinical cohort pilot study about the influence of pollen on AE between sensitized and nonsensitized subjects and an experimental study addressing the cutaneous penetration of pollen into the skin. Fifty-five patients were monitored during birch pollen season. To study the cutaneous penetration, grass pollen allergens were applied on excised skin and the uptake in CD1c-expressing dendritic cells was investigated. The correlation between environmental pollen load and severity of the Scoring Atopic Dermatitis (SCORAD score and pruritus was observed, regardless of the status of sensitization. The sensitized group recovered significantly worse after the birch pollen season. Remarkably higher amounts of pollen allergens taken up by CD1c cells were detected in epidermal cells derived from skin explants with a disturbed epidermal barrier. These findings suggest an exacerbating role of pollen in AE utilizing the epidermal route. Keywords: aeroallergens, atopic eczema, seasonality, skin antigen-presenting cells, skin barrier penetration

  8. 2. symposium energy crops 2009; 2. Symposium Energiepflanzen 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-27

    Within the meeting '2nd Symposium energy plants 2009', held at 17th to 18th November, 2009, in Berlin (Federal Republic of Germany), the following lectures were held: (1) The bio energy policy of the Federal Government in the area of attention between climatic protection, ecology and economy (Ilse Aigner); (2) Chances and threatens of cultivation of energy plants for a sustainable energy supply (Alois Heissenhuber); (3) Certification as a prerequisite of the global exploration of bio energy (Andreas Feige); (4) A project support in the field of cultivation of energy plants, a review (Andreas Schuette); (5) Results from the investigation of the crop rotation in the EVA network (Armin Vater); (6) Optimisation of the cultivation technology of sorghum millets (Christian Roehricht); (7) The two-culture utilization system - a comparison between ecologic and conventional cultivation (Reinhold Stuelpnagel); (8) Crop rotation with energy plants - Chances and threatens for the plant protection (Baerbel Gerowitt); (9) Efficiency of utilization of water for energy plants (Siegfried Schittenhelm); (10) Utilization of arable food grasses and permanent grassland as a substrate for biogas (Matthias Benke); (11) Economical evaluation of plant fermentation substrates (Dominik Reus); (12) Energy plants as a challenge for the agricultural engineering (Heiner Bruening); (13) Influence of the design of cultivation on the subsequent effects of the cultivation of energy plants (Michael Glemnitz); (14) Energy plants and waters protection - Key aspects and possible options of action (Heike Nitsch); (15) Neophytes as energy plants - Chances and threatens (Werner Kuhn); (16) Manifold in te landscape - extensive cultivation systems with renewable raw materials as an option for nature protection? (Peer Heck); (17) Ecologic aspects of agro forestry systems (Holger Gruenewald); (18) Enhancement of the potential of energy yield of winter wheat (Wolfgang Friedt); (19) Interspersed silphie

  9. Renal function in heart transplant patients after switch to combined mammalian target of rapamycin inhibitor and calcineurin inhibitor therapy

    Directory of Open Access Journals (Sweden)

    Helmschrott M

    2017-06-01

    Full Text Available Matthias Helmschrott,1 Rasmus Rivinius,1 Thomas Bruckner,2 Hugo A Katus,1 Andreas O Doesch1 1Department of Cardiology, Angiology, Pneumology, 2Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany Background: A calcineurin inhibitor (CNI-based immunosuppression combined with mammalian target of rapamycin inhibitors (mTORs seems to be attractive in patients after heart transplantation (HTX in special clinical situations, for example, in patients with adverse drug effects of prior immunosuppression. Previous studies in patients after HTX detected advantageous effects regarding renal function of a tacrolimus (TAC-based vs cyclosporine-A (CSA-based immunosuppression (in combination with mycophenolate mofetil. However, data regarding renal function after HTX in mTOR/CNI patients remain limited. Aim: Primary end point of the present study was to analyze renal function in HTX patients 1 year after switch to an mTOR/CNI-based immunosuppression. Methods: Data of 80 HTX patients after change to mTOR/CNI-based immunosuppression were retrospectively analyzed. Renal function was assessed by measured serum creatinine and by estimated glomerular filtration rate (eGFR calculated from Modification of Diet in Renal Disease equation. Results: Twenty-nine patients received mTOR/CSA-based treatment and 51 patients received mTOR/TAC-based therapy. At time of switch and at 1-year follow-up, serum creatinine and eGFR did not differ significantly between both study groups (all P=not statistically significant. Analysis of variances with repeated measurements detected a similar change of renal function in both study groups. Conclusion: The present study detected no significant differences between both mTOR/CNI study groups, indicating a steady state of renal function in HTX patients after switch of immunosuppressive regimen. Keywords: heart transplantation, cyclosporine A, tacrolimus, risk factors

  10. Public utilities with renewable energy sources. Proceedings; Stadtwerke mit Erneuerbaren Energien. Konferenzband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-09-25

    Within the 3rd EUROSOLAR Conference at 25th to 26th May, 2009, in Ludwigshafen (Federal Republic of Germany) the following lectures were held: (a) Municipal power supply - Renewable energies (Hermann Scheer); (b) The significance of municipal regulations for the development of renewable energies by the example of Rheinland-Pfalz (Gerhard Weissmueller); (c) The solar regulation of the city Marburg (Franz Kahle); (d) Large-area solar-potential register SUN-AREA, the example Osnabrueck (Martina Klaerle); (e) Energy autonomy by means of methods at municipal and state level (Stephan Grueger); (f) Concession process according to paragraph 46 EnWG as a start for a locally regenerative strategic reorientation (Christian Theobald); (g) Municipal utilities and regenerative power generation (Johannes van Bergen); (h) The hybrid power plant Enertrag (Michael Wenske); (i) Eco-power with ecological added value (Uwe Leprich); (j) Increase of added value at biogas by means of grid connection (Leonhard Thien); (k) Biogas products for private customers (Oliver Hummel); (l) Marketing of biogas as a fuel - WEGAS Wendlaender BioGas (Hans-Volker Marklewitz); (m) Geothermal heat in the Upper Rhine Graben by the example of the geothermal power plant Landau (Peter Hauffe); (n) The Act on Heating with Renewable Energy Sources - A chance for new fields of business for municipal utilities (Klara Siraki); (o) Direct marketing of electricity from renewable energies as a chance for municipal utilities (Martin Altrock, Matthias Stark); (p) The significance of EEG and EEWaermeG 2009 in the further enlargement of renewable energies (Fabio Longo); (q) Taking over of the gas grid by the municipal utility Waldkirch GmbH (Dieter Nagel); (r) Municipal added value - municipal economical effects of decentral power generation (Michael Wuebbels).

  11. Variables that influence Ironman triathlon performance – what changed in the last 35 years?

    Directory of Open Access Journals (Sweden)

    Knechtle B

    2015-08-01

    Full Text Available Beat Knechtle,1,2 Raphael Knechtle,2 Michael Stiefel,2 Matthias Alexander Zingg,2 Thomas Rosemann,2 Christoph Alexander Rüst21Gesundheitszentrum St Gallen, St Gallen, 2Institute of Primary Care, University of Zurich, Zurich, SwitzerlandObjective: This narrative review summarizes findings for Ironman triathlon performance and intends to determine potential predictor variables for Ironman race performance in female and male triathletes.Methods: A literature search was performed in PubMed using the terms “Ironman”, “triathlon”, and “performance”. All resulting articles were searched for related citations.Results: Age, previous experience, sex, training, origin, anthropometric and physiological characteristics, pacing, and performance in split disciplines were predictive. Differences exist between the sexes for anthropometric characteristics. The most important predictive variables for a fast Ironman race time were age of 30–35 years (women and men, a fast personal best time in Olympic distance triathlon (women and men, a fast personal best time in marathon (women and men, high volume and high speed in training where high volume was more important than high speed (women and men, low body fat, low skin-fold thicknesses and low circumference of upper arm (only men, and origin from the United States of America (women and men.Conclusion: These findings may help athletes and coaches to plan an Ironman triathlon career. Age and previous experience are important to find the right point in the life of a triathlete to switch from the shorter triathlon distances to the Ironman distance. Future studies need to correlate physiological characteristics such as maximum oxygen uptake with Ironman race time to investigate their potential predictive value and to investigate socio-economic aspects in Ironman triathlon.Keywords: swimming, cycling, running, age, body fat, sex

  12. Effectiveness of a low-threshold physical activity intervention in residential aged care – results of a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Cichocki M

    2015-05-01

    Full Text Available Martin Cichocki,1 Viktoria Quehenberger,1 Michael Zeiler,1 Tanja Adamcik,1 Matthias Manousek,1 Tanja Stamm,2 Karl Krajic1 1Ludwig Boltzmann Institute Health Promotion Research, 2Medical University of Vienna & University of Applied Sciences FH Campus, Wien, Vienna, Austria Purpose: Research on effectiveness of low-threshold mobility interventions that are viable for users of residential aged care is scarce. Low-threshold is defined as keeping demands on organizations (staff skills, costs and participants (health status, discipline rather low. The study explored the effectiveness of a multi-faceted, low-threshold physical activity program in three residential aged-care facilities in Austria. Main goals were enhancement of mobility by conducting a multi-faceted training program to foster occupational performance and thus improve different aspects of health-related quality of life (QoL.Participants and methods: The program consisted of a weekly session of 60 minutes over a period of 20 weeks. A standardized assessment of mobility status and health-related QoL was applied before and after the intervention. A total of 222 of 276 participants completed the randomized controlled trial study (intervention group n=104, control group n=118; average age 84 years, 88% female.Results: Subjective health status (EuroQoL-5 dimensions: P=0.001, d=0.36 improved significantly in the intervention group, and there were also positive trends in occupational performance (Canadian Occupational Performance Measure. No clear effects were found concerning the functional and cognitive measures applied.Conclusion: Thus, the low-threshold approach turned out to be effective primarily on subjective health-related QoL. This outcome could be a useful asset for organizations offering low-threshold physical activity interventions. Keywords: physical activity, intervention, residential aged care, effectiveness, aged

  13. Der grüne Weg zu Open Access: institutionelle und fachliche Repositorien / The Green Road to Open access: institutional and subject repositories

    Directory of Open Access Journals (Sweden)

    Bauer, Bruno

    2009-06-01

    Full Text Available The recent issue 1/2009 of GMS Medizin – Bibliothek – Information has a focus on „The green road to open Access: institutional and subject repositories“. Self-archiving and storing scholarly publications on a print server were also central topics in many presentations at the 9th International Bielefeld Conference in February 2009. The authors in this issue are Birgit Schmidt and Karin Ilg-Hartecke (Open Access in Deutschland – erweiterte Perspektiven für die Wissenschaft, Christoph Bruch and Anja Lengenfelder (Unterstützung des Grünen Weges zu Open Access an der Max-Planck-Gesellschaft, Ulrich Herb and Matthias Müller (Nuancen in Grün: Betrieb eines institutionellen und disziplinären Repositoriums – Erfahrungen und Entwicklungen an der Saarländischen Universitäts- und Landesbibliothek, Timo Borst and Jan B. Weiland (EconStor: ein fachliches Repositorium für die Wirtschaftswissenschaften, Antonella de Robbio and Michael Katzmayr (The management of an international open access repository: the case of E-LIS and Christian Gumpenberger (The EPrints story: Southampton as the cradle of institutional self-archiving.Furthermore this focus issue features an interview of a representative of a research funding organisation (Repositorien: Der grüne Weg zu Open Access Publishing aus der Perspektive einer Forschungsförderungsorganisation. 10 Fragen von Bruno Bauer an Falk Reckling, Mitarbeiter des FWF Der Wissenschaftsfonds and an interview of a publisher (Repositorien: Der grüne Weg zu Open Access Publishing aus der Perspektive der International Association of Scientific, Technical & Medical Publishers (STM: 10 Fragen von Bruno Bauer an Barbara Kalumenos, Director of Public Affairs bei STM.

  14. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2 study: implementation of a nationwide patient enrollment system

    Directory of Open Access Journals (Sweden)

    Nielsen JS

    2012-09-01

    Full Text Available Jens Steen Nielsen,1 Reimar W Thomsen,2 Charlotte Steffensen,2 Jens S Christiansen31Department of Endocrinology M, Odense University Hospital, Odense, 2Department of Clinical Epidemiology, 3Department of Endocrinology, Aarhus University Hospital, Aarhus, DenmarkAbstract: This paper aims to describe the patient enrollment system and implementation strategy for the new nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2 project. The paper will also describe the design, current content, and pilot testing of the DD2 registration form. The challenge of the DD2 project was to construct a registration system functioning in the entire Danish health care system, where new type 2 diabetes patients are initially met, and with the capacity to enroll 200 newly diagnosed diabetes patients per week nationwide. This requires a fast and simple registration that is part of everyday clinical practice in hospital outpatient clinics and general practitioner (GP clinics. The enrollment system is thus built on a tested, rational design where patients need only one visit and only specific limited data about physical activity, anthropometric measures, and family history of diabetes are collected during a brief patient interview. Later, supplemental data will be extracted by computerized linkage with existing databases. The feasibility of this strategy was verified in a pilot study. For maximum flexibility, three different ways to fill in the DD2 registration form were provided and an interactive webpage was constructed. The DD2 project also involves collection of blood and urine samples from each diabetes patient, to be stored in a biobank. Clinicians may obtain the samples themselves or refer patients to the nearest clinical biochemical department. GPs have the additional option of referring patients to the nearest hospital outpatient diabetes clinic to obtain interview data, clinical data, and samples. At present, the enrollment system is in use at

  15. A Healthy Eating Education Program for Midwives to Investigate and Explore Their Knowledge, Understanding, and Confidence to Support Pregnant Women to Eat Healthily: Protocol for a Mixed-Methods Study.

    Science.gov (United States)

    Othman, Shwikar Mahmoud Etman; Steen, Mary P; Jayasekara, Rasika; Fleet, Julie-Anne

    2018-05-25

    confidence to support healthy eating in pregnant women. The results and conclusions from the systematic review provided some guidance for the design and development of this study protocol. This mixed-methods study will address a gap in the literature. The results from quantitative and qualitative data sources in this proposed study will help to draw conclusions to address the research topic. RR1-10.2196/9861. ©Shwikar Mahmoud Etman Othman, Mary P Steen, Rasika Jayasekara, Julie-Anne Fleet. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 25.05.2018.

  16. Strawberry Rhyolites, Oregon: Northwestern extent of mid-Miocene flood basalt related rhyolites of the Pacific Northwest

    Science.gov (United States)

    Steiner, A. R.; Streck, M. J.

    2011-12-01

    Rhyolitic volcanism associated with the Columbia River-Steens flood basalts of the Pacific Northwest has traditionally been viewed to be centered at McDermitt caldera near the Oregon-Nevada border starting at ~16.5 Ma. In recent years, more rhyolitic centers along this latitude with ages between 16.5-15.5 Ma have been identified and associated with the inception of the Yellowstone hotspot. However the footprint of plume-head related rhyolites becomes much larger when silicic centers of mid-Miocene age in eastern Oregon are included extending the distribution of such rhyolites to areas near the towns of Baker City and John Day ~250 km north of McDermitt. This study addresses one of these rhyolitic centers that was virtually unknown and that constitutes the northwestern extent of mid-Miocene rhyolites. Rhyolites are centered ~40 km SSW of John Day and are considered part of the Strawberry Volcanic Field (SVF), which consists of a diverse group of volcanic rocks ranging from basalt to rhyolite with abundant intermediate compositions. One existing age date of 17.3 Ma ± 0.36 (Robyn, 1977) - if confirmed by our ongoing study - places these rhyolites at the very onset of plume-head related rhyolites. Strawberry rhyolitic lavas are most voluminous in the southwestern portion of the SVF covering approximately 500 km2 between Bear and Logan Valley. The rhyolitic lavas tend to be phenocryst-poor (LaN/YbN values ranging from 2.5 to 8.3 and higher values correlate positively with other differentiation indices (e.g. Ba, Sr, Eu/Eu*). Furthermore, major elements (e.g. SiO2 and FeO*) and trace elements (e.g. Ba, Sr, La, Zr/Hf) display common liquid lines of decent with Eu/Eu*. This suggests that the Strawberry Rhyolites are likely products of variable degrees of differentiation. Future petrogenetic evaluations will further investigate the origin of the Strawberry Rhyolites.

  17. Positive effects on hematological and biochemical imbalances in patients with metastatic breast cancer stage IV, of BP-C1, a new anticancer substance

    Directory of Open Access Journals (Sweden)

    Lindkær-Jensen S

    2015-03-01

    Full Text Available Steen Lindkær-Jensen,1 Stig Larsen,2 Nina Habib-Lindkær-Jensen,1 Hans E Fagertun3 1Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College, London, UK; 2Center of Epidemiology and Biostatistics, Faculty of Veterinary Medicine, University of Life Science, Oslo, Norway; 3Meddoc Research AS, Skjetten, Norway Abstract: A benzene-poly-carboxylic acid complex with cis-diammineplatinum(II dihydrocholride, BP-C1 is currently used in clinical trials in treating metastatic breast cancer. BP-C1 controls tumor growth with a few mild side-effects, improving quality of life.Methods: The data consisted of prospectively collected laboratory results from 47 patients in two controlled clinical trials of daily intramuscular injections of BP-C1 for 32 days. Study I was performed as an open, nonrandomized, Phase I dose–response, multicenter study with a three-level, between-patient, response surface pathway design. The second study was a randomized, double-blind, and placebo-controlled, multicenter study with a stratified semi-crossover design.Results: Hemoglobin (Hb and hematocrit (Hct increased significantly (P<0.01 during BP-C1 treatment, while red blood cell (RBC count increased but not significantly. The most pronounced increase in Hb, RBC, Hct, and white blood cell (WBC was in anemic patients (P≤0.01. WBC count and neutrophils increased significantly (P=0.01 in the overall data. WBCs and neutrophils (P<0.01, eosinophils (P=0.05 and monocytes (P<0.01 increased significantly and markedly in patients with lowest baseline levels. Additionally, low levels of thrombocytes significantly increased. No changes in liver parameters, amylase, glucose, creatinine, or albumin, were detected except for albumin in the subgroup with low baseline levels, where levels increased significantly (P=0.04. An increase in K+, Ca2+, and PO43- was most pronounced in patients with low baseline levels (P≤0.02. A similar pattern detected for Mg2+, prothrombin

  18. Acute radiation syndrome (ARS – treatment of the reduced host defense

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    Heslet L

    2012-01-01

    Full Text Available Lars Heslet1, Christiane Bay2, Steen Nepper-Christensen31Serendex ApS, Gentofte; 2University of Copenhagen, Medical Faculty, Copenhagen; 3Department of Head and Neck Surgery, Otorhinolaryngology, Køge University Hospital, Køge, DenmarkBackground: The current radiation threat from the Fukushima power plant accident has prompted rethinking of the contingency plan for prophylaxis and treatment of the acute radiation syndrome (ARS. The well-documented effect of the growth factors (granulocyte colony-stimulating factor [G-CSF] and granulocyte-macrophage colony-stimulating factor [GM-CSF] in acute radiation injury has become standard treatment for ARS in the United States, based on the fact that growth factors increase number and functions of both macrophages and granulocytes.Methods: Review of the current literature.Results: The lungs have their own host defense system, based on alveolar macrophages. After radiation exposure to the lungs, resting macrophages can no longer be transformed, not even during systemic administration of growth factors because G-CSF/GM-CSF does not penetrate the alveoli. Under normal circumstances, locally-produced GM-CSF receptors transform resting macrophages into fully immunocompetent dendritic cells in the sealed-off pulmonary compartment. However, GM-CSF is not expressed in radiation injured tissue due to defervescence of the macrophages. In order to maintain the macrophage’s important role in host defense after radiation exposure, it is hypothesized that it is necessary to administer the drug exogenously in order to uphold the barrier against exogenous and endogenous infections and possibly prevent the potentially lethal systemic infection, which is the main cause of death in ARS.Recommendation: Preemptive treatment should be initiated after suspected exposure of a radiation dose of at least ~2 Gy by prompt dosing of 250–400 µg GM-CSF/m2 or 5 µg/kg G-CSF administered systemically and concomitant inhalation of

  19. Danish Register of chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Lange P

    2016-10-01

    Full Text Available Peter Lange,1,2 Sandra Søgaard Tøttenborg,1 Anne Dichmann Sorknæs,3 Jørgen Steen Andersen,4 Mette Søgaard,5 Henrik Nielsen,5 Reimar Wernich Thomsen,5 Katrine Abildtrup Nielsen6 1Section of Social Medicine, Department of Public Health, University of Copenhagen, 2Lung Diseases Department, Respiratory Medicine Section, Lung Diseases Department, Hvidovre Hospital, University of Copenhagen, Copenhagen, 3Medical Department, Odense Universitetshospital–Svendborg Hospital, Svendborg, 4Danish College of General Practitioners, Copenhagen, 5Department of Clinical Epidemiology, Aarhus University Hospital, 6Registry Support Centre of Clinical Quality and Health Informatics (West, Århus, Denmark Aim of database: The Danish Register of Chronic Obstructive Pulmonary Disease (DrCOPD is a nationwide database aiming to describe the quality of treatment of all patients with chronic obstructive pulmonary disease (COPD in Denmark. Study population: DrCOPD comprises data on all patients with a diagnosis of COPD. In the hospital setting, both in- and outpatients are included. In the setting of the general practice (GP, DrCOPD aims to include all patients with a COPD diagnosis who attend an annual control visit for COPD. Main variables: DrCOPD includes information on forced expiratory volume in 1 second, smoking status, body mass index, dyspnea, treatment modalities such as rehabilitation, smoking cessation, medical treatment, and the use of noninvasive ventilation during hospitalization due to exacerbations. The outcome variables include frequency of readmission and death 30 days after discharge from hospital. Descriptive data: Since 2008, the registration in the Danish hospitals has gradually become more comprehensive. In 2014, ~90% of 16,106 eligible patients had complete data sets that showed an improvement in the processes describing quality of care, including increased offering of smoking cessation, rehabilitation, and correct treatment with inhaled

  20. New national Biobank of The Danish Center for Strategic Research on Type 2 Diabetes (DD2

    Directory of Open Access Journals (Sweden)

    Christensen H

    2012-09-01

    Full Text Available Henry Christensen,1 Jens Steen Nielsen,2 Karina Meden Sørensen,3 Mads Melbye,3 Ivan Brandslund1,41Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark; 2The Danish Centre for Strategic Research in Type 2 Diabetes (DD2, Department of Endocrinology M, Diabetes Research Centre, Odense University Hospital, Odense, Denmark; 3Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; 4Institute of Regional Health Research, University of Southern Denmark, Odense, DenmarkAbstract: Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2, aims to improve treatment and the long-term outcome of patients with newly diagnosed type 2 diabetes (T2D. The DD2 project includes establishment of a biobank with samples from 50,000 patients with newly diagnosed T2D. This paper describes how blood and urine samples from 10,000 patients per year are collected, handled, and stored. The biobank includes whole blood, DNA, and plasma and urine samples, all frozen at −80°C. Sampling tubes have been standardized and are sent to hospital outpatient clinics and general practitioners where samples are taken, handled, aliquoted, and returned by mail overnight in standardized cryostorage tubes. When received at the biobank, samples are frozen without further treatment. From each patient, 24 cryostorage tubes are stored. Each tube is labeled with a barcode that links the data to other information available in a clinical databank registry. When patients are enrolled in DD2, a questionnaire is filled out and a quality monitoring system ensures that patients, samples, and questionnaires can be linked together at all times. The biobank is located at Vejle Hospital and the Danish National Biobank at Statens Serum Institut. As of the end of March 2012

  1. Geology of the Mid-Miocene Rooster Comb Caldera and Lake Owyhee Volcanic Field, eastern Oregon: Silicic volcanism associated with Grande Ronde flood basalt

    Science.gov (United States)

    Benson, Thomas R.; Mahood, Gail A.

    2016-01-01

    contemporaneous with the latest stages of eruptions nearby. High Rock and McDermitt rhyolites are associated with propagation of Steens Basalt dikes to the south, and LOVF rhyolites with later propagation of Grande Ronde Basalt dikes to the north and north-northwest.

  2. Budget impact analysis of two immunotherapy products for treatment of grass pollen-induced allergic rhinoconjunctivitis

    Directory of Open Access Journals (Sweden)

    Rønborg SM

    2012-09-01

    Full Text Available Steen M Rønborg,1 Ulrik G Svendsen,2 Jesper S Micheelsen,3 Lars Ytte,4 Jakob N Andreasen,5 Lars Ehlers61The Pulmonology and Allergy Clinic of Copenhagen, Copenhagen, 2Bispebjerg Hospital, Copenhagen, 3Private ENT practice, Aalborg, 4General Practice Aalborg, 5ALK, Hørsholm, 6Aalborg University, Aalborg, DenmarkBackground: Grass pollen-induced allergic rhinoconjunctivitis constitutes a large burden for society. Up to 20% of European and United States (US populations suffer from respiratory allergies, including grass pollen-induced allergic rhinoconjunctivitis. The majority of patients are treated with symptomatic medications; however, a large proportion remains uncontrolled despite use of such treatments. Specific immunotherapy is the only treatment documented to target the underlying cause of the disease, leading to a sustained effect after completion of treatment. The aim of this study was to compare the economic consequences of treating patients suffering from allergic rhinoconjunctivitis with either a grass allergy immunotherapy tablet (AIT or subcutaneous immunotherapy (SCIT.Methods: A budget impact analysis was applied comparing SQ-standardized grass AIT (Grazax®; Phleum pratense, 75,000 SQ-T/2,800 BAU; ALK, Denmark with SCIT (Alutard®; P. pratense, 100,000 SQ-U/mL; ALK, Denmark. Budget impact analysis included health care utilization measured in physical units based on systematic literature reviews, guidelines, and expert opinions, as well as valuation in unit costs based on drug tariffs, physician fees, and wage statistics. Budget impact analysis was conducted from a Danish health care perspective.Results: Treating patients suffering from allergic rhinoconjunctivitis with grass AIT instead of grass SCIT resulted in a total reduction in treatment costs of €1291 per patient during a treatment course. This cost saving implies that approximately 40% more patients could be treated with grass AIT per year without influencing the cost of

  3. Survey Email Scheduling and Monitoring in eRCTs (SESAMe): A Digital Tool to Improve Data Collection in Randomized Controlled Clinical Trials.

    Science.gov (United States)

    Skonnord, Trygve; Steen, Finn; Skjeie, Holgeir; Fetveit, Arne; Brekke, Mette; Klovning, Atle

    2016-11-22

    Electronic questionnaires can ease data collection in randomized controlled trials (RCTs) in clinical practice. We found no existing software that could automate the sending of emails to participants enrolled into an RCT at different study participant inclusion time points. Our aim was to develop suitable software to facilitate data collection in an ongoing multicenter RCT of low back pain (the Acuback study). For the Acuback study, we determined that we would need to send a total of 5130 emails to 270 patients recruited at different centers and at 19 different time points. The first version of the software was tested in a pilot study in November 2013 but was unable to deliver multiuser or Web-based access. We resolved these shortcomings in the next version, which we tested on the Web in February 2014. Our new version was able to schedule and send the required emails in the full-scale Acuback trial that started in March 2014. The system architecture evolved through an iterative, inductive process between the project study leader and the software programmer. The program was tested and updated when errors occurred. To evaluate the development of the software, we used a logbook, a research assistant dialogue, and Acuback trial participant queries. We have developed a Web-based app, Survey Email Scheduling and Monitoring in eRCTs (SESAMe), that monitors responses in electronic surveys and sends reminders by emails or text messages (short message service, SMS) to participants. The overall response rate for the 19 surveys in the Acuback study increased from 76.4% (655/857) before we introduced reminders to 93.11% (1149/1234) after the new function (P<.001). Further development will aim at securing encryption and data storage. The SESAMe software facilitates consecutive patient data collection in RCTs and can be used to increase response rates and quality of research, both in general practice and in other clinical trial settings. ©Trygve Skonnord, Finn Steen, Holgeir

  4. Labeling of mesenchymal stem cells for MRI with single-cell sensitivity

    Directory of Open Access Journals (Sweden)

    Ariza de Schellenberger A

    2016-04-01

    Full Text Available Angela Ariza de Schellenberger,1 Harald Kratz,1 Tracy D Farr,2,3 Norbert Löwa,4 Ralf Hauptmann,1 Susanne Wagner,1 Matthias Taupitz,1 Jörg Schnorr,1 Eyk A Schellenberger1 1Department of Radiology, 2Department of Experimental Neurology, Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, Berlin, Germany; 3School of Life Sciences, University of Nottingham, Medical School, Nottingham, UK; 4Department of Biomagnetic Signals, Physikalisch-Technische Bundesanstalt Berlin, Berlin, Germany Abstract: Sensitive cell detection by magnetic resonance imaging (MRI is an important tool for the development of cell therapies. However, clinically approved contrast agents that allow single-cell detection are currently not available. Therefore, we compared very small iron oxide nanoparticles (VSOP and new multicore carboxymethyl dextran-coated iron oxide nanoparticles (multicore particles, MCP designed by our department for magnetic particle imaging (MPI with discontinued Resovist® regarding their suitability for detection of single mesenchymal stem cells (MSC by MRI. We achieved an average intracellular nanoparticle (NP load of >10 pg Fe per cell without the use of transfection agents. NP loading did not lead to significantly different results in proliferation, colony formation, and multilineage in vitro differentiation assays in comparison to controls. MRI allowed single-cell detection using VSOP, MCP, and Resovist® in conjunction with high-resolution T2*-weighted imaging at 7 T with postprocessing of phase images in agarose cell phantoms and in vivo after delivery of 2,000 NP-labeled MSC into mouse brains via the left carotid artery. With optimized labeling conditions, a detection rate of ~45% was achieved; however, the experiments were limited by nonhomogeneous NP loading of the MSC population. Attempts should be made to achieve better cell separation for homogeneous NP loading and to thus improve NP

  5. Nicoboxil/nonivamide cream effectively and safely reduces acute nonspecific low back pain – a randomized, placebo-controlled trial

    Directory of Open Access Journals (Sweden)

    Blahova Z

    2016-12-01

    Full Text Available Zuzana Blahova,1 Janina Claudia Holm,1 Thomas Weiser,2 Erika Richter,2 Matthias Trampisch,2 Elena Akarachkova3 1Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria; 2Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim am Rhein, Germany; 3I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation Background/objective: Low back pain affects many patients and has a high socioeconomic impact. Topical capsaicinoids have been used for decades to treat musculoskeletal pain. This study investigated the effects of the fixed dose combination (FDC of nonivamide (a capsaicinoid and nicoboxil (a nicotinic acid ester cream in the treatment of acute nonspecific low back pain.Materials and methods: This phase III randomized, double-blind, placebo-controlled, multinational, multi-center trial investigated efficacy, safety, and tolerability of topical nicoboxil 1.08%/nonivamide 0.17% (Finalgon® cream in treatment of acute nonspecific low back pain with the endpoints: pain intensity (PI difference between pre-dose baseline and 8 hours after first application and the end of treatment, mobility score, and efficacy score.Results: Patients (n=138, 21–65 years of age, were treated for up to 4 days with FDC or placebo cream. Mean baseline PI was 6.8 on a 0–10 point numerical rating scale. After 8 hours, pain was more reduced with the FDC than with placebo (adjusted means: 2.824 vs. 0.975 points; p<0.0001. On the last treatment day, mean pain reduction by the FDC was stronger than with placebo (adjusted means: 5.132 vs. 2.174 points; p<0.0001. Mobility on Day 1 was in favor of the FDC when compared to placebo (odds ratio [95% confidence interval {CI}]: 7.200 [3.609, 14.363], p<0.0001. At the end of treatment, patients treated with the FDC rated efficacy significantly higher than placebo (odds ratio [95% CI]: 11.370 [5.342, 24.199], p<0.0001. Both treatments were tolerated well. No serious adverse events were reported.Conclusion: Nicoboxil

  6. Vegetation and land carbon feedbacks in the high-resolution transient Holocene simulations using the MPI Earth system model

    Science.gov (United States)

    Brovkin, Victor; Lorenz, Stephan; Raddatz, Thomas

    2017-04-01

    üger1, Roberta D'agostino1, Anne Dallmeyer1, Sabine Egerer1, Vivienne Groner1, Matthias Heinze1, Tatiana Ilyina1, Johann Jungclaus1, Thomas Kleinen1, Alexander Lemburg1, Stephan Lorenz1, Thomas Raddatz1, Hauke Schmidt1, Gerhard Schmiedl3, Bjorn Stevens1, Claudia Timmreck1, Matthew Toohey4 1Max-Planck-Institut für Meteorologie, D 2Wageningen University, NL 3CEN, Universität Hamburg, D 4GEOMAR Helmholtz Zentrum für Ozeanforschung Kiel, D

  7. Stress coupling in the seismic cycle indicated from geodetic measurements

    Science.gov (United States)

    Wang, L.; Hainzl, S.; Zoeller, G.; Holschneider, M.

    2012-12-01

    Wang, Sebastian Hainzl, Gert Zöller, Matthias Holschneider, M., 2012. Stress- and aftershock- constrained joint inversions for co- and post- seismic slip applied to the 2004 M6.0 Parkfield earthquake. J. Geophys. Res. doi:10.1029/2011JB009017.

  8. Holocene climate change in North Africa and the end of the African humid period - results of new high-resolution transient simulations with the MPI-ESM 1.3

    Science.gov (United States)

    Dallmeyer, Anne; Claussen, Martin; Lorenz, Stephan

    2017-04-01

    The Max-Planck-Institute for Meteorology has recently undertaken high-resolution transient Holocene simulations using the fully-coupled Earth System Model MPI-ESM 1.3. The simulations cover the last 8000 years and are forced not only by reconstructed Holocene orbital variations and atmospheric greenhouse gas concentrations, but also by recent compilations of Holocene volcanic aerosol distributions, variations in spectral solar irradiance, stratospheric ozone and land-use change. The simulations reveal the ubiquitous "Holocene conundrum": simulated global mean temperatures increase during the mid-Holocene and stay constant during the late Holocene. Simulated mid-Holocene near-surface temperatures are too cold in large parts of the world. Simulated precipitation, however, agrees much better with reconstruction than temperatures do. Likewise simulated global biome pattern fit reconstructions nicely, except for North Western America. First results of these simulations are presented with the main focus on the North African monsoon region. The amplitude of the mid-Holocene African Humid Period (AHP) is well captured in terms of precipitation and vegetation cover, so is the south-ward transgression of the termination of the AHP seen in reconstructions. The Holocene weakening and southward retreat of the North African monsoon as well as changes in the monsoon dynamic including shifts in the seasonal cycle and their relation to the locally varying termination of the AHP are discussed in detail. Members of the Hamburg Holocene Team: Jürgen Bader (1), Sebastian Bathiany (2), Victor Brovkin (1), Martin Claussen (1,3), Traute Crüger (1), Roberta D'agostino (1), Anne Dallmeyer (1), Sabine Egerer (1), Vivienne Groner (1), Matthias Heinze (1), Tatiana Ilyina (1), Johann Jungclaus (1), Thomas Kleinen (1), Alexander Lemburg (1), Stephan Lorenz (1), Thomas Raddatz (1), Hauke Schmidt (1), Gerhard Schmiedl (3), Bjorn Stevens (1), Claudia Timmreck (1), Matthew Toohey (4) (1) Max

  9. Effectiveness of various formulations of local anesthetics and additives for topical anesthesia – a prospective, randomized, double-blind, placebo-controlled study

    Directory of Open Access Journals (Sweden)

    Weilbach C

    2017-05-01

    Full Text Available Christian Weilbach,1 Christian Hoppe,2 Matthias Karst,3 Michael Winterhalter,4 Konstantinos Raymondos,3 Arthur Schultz,3 Niels Rahe-Meyer2 1Department of Anesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, St. Josefs-Hospital Cloppenburg, Cloppenburg, 2Clinic for Anesthesiology and Operational Intensive Care, Franziskus Hospital Bielefeld, Bielefeld, 3Clinic for Anesthesiology and Intensive Care, Medizinische Hochschule Hannover, Hannover, 4Clinic for Anesthesiology and Pain Therapy, Klinikum Bremen-Mitte, Bremen, Germany Background: Topical anesthesia is used to control pain associated with many procedures in medicine. Today, the product most commonly applied for topical anesthesia in Germany is EMLA® (lidocaine/prilocaine. However, since prilocaine is a methemoglobin-inducing agent, there are limitations to its use, especially in neonates and infants. The aim of this study was to evaluate the effect of prilocaine and lidocaine as well as propylene glycol, a penetration enhancer, and trometamol, a buffer substance, in anesthetic creams.Patients and methods: Twenty-nine healthy adults participated in this study. Standardized creams with eight different compositions were applied and left for 20, 40 or 60 min. After exposure to standardized painful stimuli (blunt/sharp with pressures of 0.2, 0.4 or 0.8 N, subjects rated the experimental pain using a visual analog scale.Results: Significant results were only found with an exposure time of 60 min and a stamp pressure of 0.8 N. At a concentration of 20%, lidocaine was more effective compared to placebo and equally effective compared to lidocaine/prilocaine in controlling pain. The analgesic effect of the cream containing lidocaine 10% and additional trometamol was significantly superior to that of placebo and non-inferior to that of lidocaine/prilocaine. In this study, the penetration enhancer propylene glycol did not accelerate the onset of the analgesic effect. In contrast

  10. Patients' and partners' perspectives of chronic illness and its management.

    Science.gov (United States)

    Checton, Maria G; Greene, Kathryn; Magsamen-Conrad, Kate; Venetis, Maria K

    2012-06-01

    This study is framed in theories of illness uncertainty (Babrow, A. S., 2007, Problematic integration theory. In B. B. Whaley & W. Samter (Eds.), Explaining communication: Contemporary theories and exemplars (pp. 181-200). Mahwah, NJ: Erlbaum; Babrow & Matthias, 2009; Brashers, D. E., 2007, A theory of communication and uncertainty management. In B. B. Whaley & W. Samter (Eds.), Explaining communication: Contemporary theories and exemplars (pp. 201-218). Mahwah, NJ: Erlbaum; Hogan, T. P., & Brashers, D. E. (2009). The theory of communication and uncertainty management: Implications for the wider realm of information behavior. In T. D. Afifi & W. A. Afifi (Eds.), Uncertainty and information regulation in interpersonal contexts: Theories and applications, (pp. 45-66). New York, NY: Routledge; Mishel, M. H. (1999). Uncertainty in chronic illness. Annual Review of Nursing Research, 17, 269-294; Mishel, M. H., & Clayton, M. F., 2003, Theories of uncertainty. In M. J. Smith & P. R. Liehr (Eds.), Middle range theory for nursing (pp. 25-48). New York, NY: Springer) and health information management (Afifi, W. A., & Weiner, J. L., 2004, Toward a theory of motivated information management. Communication Theory, 14, 167-190. doi:10.1111/j.1468-2885.2004.tb00310.x; Greene, K., 2009, An integrated model of health disclosure decision-making. In T. D. Afifi & W. A. Afifi (Eds.), Uncertainty and information regulation in interpersonal contexts: Theories and applications (pp. 226-253). New York, NY: Routledge) and examines how couples experience uncertainty and interference related to one partner's chronic health condition. Specifically, a model is hypothesized in which illness uncertainty (i.e., stigma, prognosis, and symptom) and illness interference predict communication efficacy and health condition management. Participants include 308 dyads in which one partner has a chronic health condition. Data were analyzed using structural equation modeling. Results indicate that there

  11. The improved quality of postoperative analgesia after intrathecal morphine does not result in improved recovery and quality of life in the first 6 months after orthopedic surgery: a randomized controlled pilot study

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    Foadi N

    2017-05-01

    Full Text Available Nilufar Foadi,1,* Matthias Karst,1,* Anika Frese-Gaul,2 Niels Rahe-Meyer,3 Stefan Krömer,1 Christian Weilbach 4 1Department of Anesthesiology and Intensive Care Medicine, Pain Clinic, Hannover Medical School, Hannover, 2Department of Psychosomatic Medicine, AHG Psychosomatische Klinik Bad Pyrmont, Bad Pyrmont, 3Department of Anesthesiology and Operative Intensive Care Medicine, Franziskus Hospital, Bielefeld, 4Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, St. Josefs‑Hospital Cloppenburg, Cloppenburg, Germany *These authors contributed equally to this work Objective: In orthopedic surgery, it is well known that the use of intrathecal morphine (ITM leads to an improved quality of postoperative analgesia. Little is known how this improved analgesia affects the long-term course after surgery.Study design: A randomized, double-blind trial.Setting: Academic medical center.Subjects: Forty-nine patients undergoing total hip or knee replacement surgery in spinal anesthesia.Methods: Patients were randomly assigned to receive either 0.1 mg (n=16 or 0.2 mg (n=16 morphine sulfate intrathecally or physiological saline (n=17 added to 3 mL 0.5% isobaric bupivacaine for spinal anesthesia. As a function of the quality of the short-term postoperative analgesia, the effect on recovery and quality of life was evaluated at various time points up to 26 weeks after surgery.Results: In both ITM groups, the additionally required postoperative systemic morphine dose was significantly reduced compared with the placebo group (P=0.004. One week after operation, patients with ITM reported significantly less pain at rest (P=0.01 compared to the placebo group. At discharge, in comparison with the 0.1 mg ITM and placebo group, the 0.2 mg ITM group showed a higher degree of impairment regarding pain, stiffness, and physical function of the respective joint (P=0.02. Over the further follow-up period of 6 months after surgery

  12. Conference on participatory wind energy in France and in Germany

    International Nuclear Information System (INIS)

    Vohrer, Philipp; Poize, Noemie; Hanus, Dominik; Hallmann, Dieter; Jourdain, Pierre; Ruehl, Martin; Bessiere, Patrick; Guyonnet-Duperat, Philippe; Foerster, Maelle; Partetzke, Matthias; Rumolino, Claudio

    2014-01-01

    profitable: citizen involvement in Germany and France. Successfully financing (real) citizen wind parks in Germany. What really counts (Matthias Partetzke); 10 - Participatory Investment in Renewable energies in France: General overview, VALOREM's projects (Claudio Rumolino)

  13. Clinical trial simulation methods for estimating the impact of DPP-4 inhibitors on cardiovascular disease

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    Schuetz CA

    2015-06-01

    Full Text Available Charles Andy Schuetz,1 Siew Hwa Ong,2 Matthias Blüher3 1Evidera Inc., Bethesda, MD, USA; 2Novartis Pharma AG, Basel, Switzerland; 3Department of Medicine, University of Leipzig, Leipzig, Germany Introduction: Dipeptidyl peptidase-4 (DPP-4 inhibitors are a class of oral antidiabetic agents for the treatment of type 2 diabetes mellitus, which lower blood glucose without causing severe hypoglycemia. However, the first cardiovascular (CV safety trials have only recently reported their results, and our understanding of these therapies remains incomplete. Using clinical trial simulations, we estimated the effectiveness of DPP-4 inhibitors in preventing major adverse cardiovascular events (MACE in a population like that enrolled in the SAVOR-TIMI (the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus – Thrombolysis in Myocardial Infarction 53 trial. Methods: We used the Archimedes Model to simulate a clinical trial of individuals (N=11,000 with diagnosed type 2 diabetes and elevated CV risk, based on established disease or multiple risk factors. The DPP-4 class was modeled with a meta-analysis of HbA1c and weight change, pooling results from published trials of alogliptin, linagliptin, saxagliptin, sitagliptin, and vildagliptin. The study treatments were added-on to standard care, and outcomes were tracked for 20 years. Results: The DPP-4 class was associated with an HbA1c drop of 0.66% (0.71%, 0.62% and a weight drop of 0.14 (-0.07, 0.36 kg. These biomarker improvements produced a relative risk (RR for MACE at 5 years of 0.977 (0.968, 0.986. The number needed to treat to prevent one occurrence of MACE at 5 years was 327 (233, 550 in the elevated CV risk population. Conclusion: Consistent with recent trial publications, our analysis indicates that DPP-4 inhibitors do not increase the risk of MACE relative to the standard of care. This study provides insights about the long-term benefits of DPP-4 inhibitors and

  14. German-austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn - update 2008

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    Buchholz Bernd

    2009-11-01

    Full Text Available Abstract German-Austrian recommendations for HIV1-therapy in pregnancy - Update 2008 Bernd Buchholz (University Medical Centre Mannheim, Pediatric Clinic, Matthias Beichert (Mannheim, Gynecology and Obstetrics Practice, Ulrich Marcus (Robert Koch Institute, Berlin, Thomas Grubert, Andrea Gingelmaier (Gynecology Clinic of the Ludwig Maximilians University of Munich, Dr. med. Annette Haberl (HIV-Department, J. W. Goethe-University Hospital, Frankfurt, Dr. med. Brigitte Schmied (Otto-Wagner Spital, Wien. In Germany during the last years about 200-250 HIV1-infected pregnant women delivered a baby each year, a number that is currently increasing. To determine the HIV-status early in pregnancy voluntary HIV-testing of all pregnant women is recommended in Germany and Austria as part of prenatal care. In those cases, where HIV1-infection was known during pregnancy, since 1995 the rate of vertical transmission of HIV1 was reduced to 1-2%. This low transmission rate has been achieved by the combination of anti-retroviral therapy of pregnant women, caesarean section scheduled before onset of labour, anti-retroviral post exposition prophylaxis in the newborn and refraining from breast-feeding by the HIV1-infected mother. To keep pace with new results in research, approval of new anti-retroviral drugs and changes in the general treatment recommendations for HIV1-infected adults, in 1998, 2001, 2003 and 2005 an interdisciplinary consensus meeting was held. Gynaecologists, infectious disease specialists, paediatricians, pharmacologists, virologists and members of the German AIDS Hilfe (NGO were participating in this conference to update the prevention strategies. A fifth update became necessary in 2008. The updating process was started in January 2008 and was terminated in September 2008. The guidelines provide new recommendations on the indication and the starting point for HIV-therapy in pregnancies without complications, drugs and drug combinations to be

  15. Individual difficulties and resources – a qualitative analysis in patients with advanced lung cancer and their relatives

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    Sparla A

    2016-10-01

    Full Text Available Anika Sparla,1 Sebastian Flach-Vorgang,1 Matthias Villalobos,2 Katja Krug,1 Martina Kamradt,1 Kadiatou Coulibaly,1 Joachim Szecsenyi,1 Michael Thomas,2 Sinikka Gusset-Bährer,2 Dominik Ose1,3 1Department of General Practice and Health Services Research, Heidelberg University Hospital, 2Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H, Member of the German Center for Lung Research, Heidelberg, Germany; 3University of Utah, Department of Population Health Sciences, Health System Innovation and Research, Salt Lake City, UT, USA Purpose: Lung cancer is a disease with a high percentage of patients diagnosed in an advanced stage. In a situation of palliative treatment, both patients and their relatives experience diverse types of distress and burden. Little research has been done to identify the individual difficulties and resources for patients with advanced lung cancer and their relatives. Especially, standardized questionnaire-based exploration may not assess the specific distressing issues that pertain to each individual on a personal level. The purpose of this qualitative study is to explore and compare individual difficulties and resources for lung cancer patients and their relatives within the palliative care context.Methods: Data were collected by qualitative interviews. A total of 18 participants, nine patients diagnosed with advanced lung cancer (International Classification of Diseases, tenth edition, diagnosis C-34, stage IV starting or receiving palliative treatment and nine relatives, were interviewed. Data were interpreted through qualitative content analysis.Results: We identified four main categories of difficulties: communication and conflicts, home and everyday life, thinking about cancer, and treatment trajectory. In general, difficulties were related to interpersonal relationships as well as to impact of chemotherapy. Family

  16. Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation

    Directory of Open Access Journals (Sweden)

    Rivinius R

    2016-02-01

    Full Text Available Rasmus Rivinius,1 Matthias Helmschrott,1 Arjang Ruhparwar,2 Bastian Schmack,2 Christian Erbel,1 Christian A Gleissner,1 Mohammadreza Akhavanpoor,1 Lutz Frankenstein,1 Fabrice F Darche,1 Patrick A Schweizer,1 Dierk Thomas,1 Philipp Ehlermann,1 Tom Bruckner,3 Hugo A Katus,1 Andreas O Doesch1 1Department of Cardiology, Angiology and Pneumology, 2Department of Cardiac Surgery, Heidelberg University Hospital, 3Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany Background: Amiodarone is a frequently used antiarrhythmic drug in patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been controversially discussed, with divergent results regarding morbidity and mortality after heart transplantation (HTX.Aim: The aim of this study was to investigate the effects of long-term use of amiodarone before HTX on early post-transplant atrial fibrillation (AF and mortality after HTX.Methods: Five hundred and thirty patients (age ≥18 years receiving HTX between June 1989 and December 2012 were included in this retrospective single-center study. Patients with long-term use of amiodarone before HTX (≥1 year were compared to those without long-term use (none or <1 year of amiodarone. Primary outcomes were early post-transplant AF and mortality after HTX. The Kaplan–Meier estimator using log-rank tests was applied for freedom from early post-transplant AF and survival.Results: Of the 530 patients, 74 (14.0% received long-term amiodarone therapy, with a mean duration of 32.3±26.3 months. Mean daily dose was 223.0±75.0 mg. Indications included AF, Wolff–Parkinson–White syndrome, ventricular tachycardia, and ventricular fibrillation. Patients with long-term use of amiodarone before HTX had significantly lower rates of early post-transplant AF (P=0.0105. Further, Kaplan–Meier analysis of freedom from early post-transplant AF showed significantly lower rates of AF in this

  17. Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy

    Directory of Open Access Journals (Sweden)

    Unterweger H

    2015-11-01

    Full Text Available Harald Unterweger,1 Daniel Subatzus,1 Rainer Tietze,1 Christina Janko,1 Marina Poettler,1 Alfons Stiegelschmitt,2 Matthias Schuster,3 Caroline Maake,4 Aldo R Boccaccini,5 Christoph Alexiou11ENT Department, Section of Experimental Oncology and Nanomedicine (SEON, Else Kröner-Fresenius-Stiftung Professorship, University Hospital Erlangen; 2Institute of Glass and Ceramics, Department of Materials Science and Engineering, University Erlangen-Nuremberg, 3Materials for Electronics and Energy Technology, Department of Materials Science and Engineering, University Erlangen-Nürnberg, Erlangen, Germany; 4Institute of Anatomy, University of Zurich, Winterthurerstr, Zurich, Switzerland; 5Institute of Biomaterials, Department of Materials Science and Engineering, University Erlangen-Nuremberg, Erlangen, Germany Abstract: Combining the concept of magnetic drug targeting and photodynamic therapy is a promising approach for the treatment of cancer. A high selectivity as well as significant fewer side effects can be achieved by this method, since the therapeutic treatment only takes place in the area where accumulation of the particles by an external electromagnet and radiation by a laser system overlap. In this article, a novel hypericin-bearing drug delivery system has been developed by synthesis of superparamagnetic iron oxide nanoparticles (SPIONs with a hypericin-linked functionalized dextran coating. For that, sterically stabilized dextran-coated SPIONs were produced by coprecipitation and crosslinking with epichlorohydrin to enhance stability. Carboxymethylation of the dextran shell provided a functionalized platform for linking hypericin via glutaraldehyde. Particle sizes obtained by dynamic light scattering were in a range of 55–85 nm, whereas investigation of single magnetite or maghemite particle diameter was performed by transmission electron microscopy and X-ray diffraction and resulted in approximately 4.5–5.0 nm. Surface chemistry of those

  18. Severely Burdened Individuals Do Not Need to Be Excluded From Internet-Based and Mobile-Based Stress Management: Effect Modifiers of Treatment Outcomes From Three Randomized Controlled Trials.

    Science.gov (United States)

    Weisel, Kiona Krueger; Lehr, Dirk; Heber, Elena; Zarski, Anna-Carlotta; Berking, Matthias; Riper, Heleen; Ebert, David Daniel

    2018-06-19

    Although internet-based and mobile-based stress management interventions (iSMIs) may be a promising strategy to reach employees suffering from high chronic stress, it remains unknown whether participants with high symptom severity of depression or anxiety also benefit from iSMIs or should be excluded. This study aimed to evaluate the efficacy of iSMIs in subgroups with high symptom severity and to test whether baseline symptom severity moderates treatment outcome. Data from three randomized controlled trials (N=791) were pooled to identify effect modifiers and to evaluate efficacy in subgroups with different levels of initial symptom severity. The outcomes perceived stress (Perceived Stress Scale, PSS), depression severity (Center for Epidemiological Depression Scale, CES-D), and anxiety (Hospital Anxiety and Depression Scale, HADS) symptom severity were assessed at baseline, 7-week postassessment, and 6-month follow-up. Potential moderators were tested in predicting differences in the change of outcome in multiple moderation analyses. Simple slope analyses evaluated efficacy of the iSMI comparing the intervention group with the waitlist control group in subgroups with low, moderate, and severe initial symptomology based on means and SDs of the study population. In addition, subgroups with clinical values of depression (CES-D≥16) and anxiety (HADS≥8) at baseline were explored, and response rates (RRs; 50% symptom reduction) and symptom-free (SF) status (CES-Dhttps://www.drks.de/DRKS00005112 (Archived by WebCite at http://www.webcitation.org/6zmIZwvdA); 2) German Clinical Trials Register DRKS00005384; https://www.drks.de/ DRKS00005384 (Archived by WebCite at http://www.webcitation.org/6zmIerdtr); and 3) German Clinical Trials Register DRKS00004749; https://www.drks.de/DRKS00004749 (Archived by WebCite at http://www.webcitation.org/6zmIjDQPx). ©Kiona Krueger Weisel, Dirk Lehr, Elena Heber, Anna-Carlotta Zarski, Matthias Berking, Heleen Riper, David Daniel Ebert

  19. Satisfying Product Features of a Fall Prevention Smartphone App and Potential Users' Willingness to Pay: Web-Based Survey Among Older Adults.

    Science.gov (United States)

    Rasche, Peter; Mertens, Alexander; Brandl, Christopher; Liu, Shan; Buecking, Benjamin; Bliemel, Christopher; Horst, Klemens; Weber, Christian David; Lichte, Philipp; Knobe, Matthias

    2018-03-27

    after all 17 product features were rated and revealed a median monthly payment WTP rate of €5.00 (interquartile range 10.00). The results show various motivating product features that should be incorporated into a fall prevention smartphone app. Results reveal aspects that fall prevention and intervention designers should keep in mind to encourage individuals to start joining their program and facilitate long-term user engagement, resulting in a greater interest in fall risk prevention. ©Peter Rasche, Alexander Mertens, Christopher Brandl, Shan Liu, Benjamin Buecking, Christopher Bliemel, Klemens Horst, Christian David Weber, Philipp Lichte, Matthias Knobe. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 27.03.2018.

  20. Refractive outcomes of an advanced aspherically optimized profile for myopia corrections by LASIK: a retrospective comparison with the standard aspherically optimized profile

    Directory of Open Access Journals (Sweden)

    Meyer B

    2015-02-01

    Full Text Available Bertram Meyer,1 Georg Sluyterman van Langeweyde,2 Matthias Wottke2 1Augencentrum Köln, Cologne, Germany; 2Carl Zeiss Meditec AG, Jena, Germany Purpose: A retrospective comparison of refractive outcomes of a new, aspherically optimized profile with an enhanced energy correction feature (Triple-A and the conventionally used aspherically optimized profile (ASA, or aberration smart ablation for correction of low-to-high myopia.Setting: Augen-OP-Centrum, Cologne, GermanyDesign: Retrospective nonrandomized comparative studyMethods: A central database at the Augen-OP-Centrum was used to gather retrospective data for low-to-high myopia (up to -10 D. One hundred and seven eyes (56 patients were treated with the ASA profile, and 79 eyes (46 patients were treated with the Triple-A profile. Postoperative outcomes were evaluated at 1 month, 3 months, 6 months, and 1 year follow-up time points.Results: The Triple-A profile showed better predictability indicated by a significantly lower standard deviation of residuals (0.32–0.34 vs 0.36–0.44, Triple-A vs ASA in the 6-month to 1-year period. The Triple-A group had better stability across all time intervals and achieved better postoperative astigmatism improvements with significantly lower scatter. This group achieved better safety at 1 year, with 100% of eyes showing no change or gain in Snellen lines, compared with 97% in the ASA group. A better safety index was observed for the Triple-A group at later time points. The Triple-A group had a better efficacy index and a higher percentage of eyes with an uncorrected Snellen visual acuity of 20/20 or greater at all investigated follow-up time points.Conclusion: The new aspherically optimized Triple-A profile can safely and effectively correct low-to-high myopia. It has demonstrated superiority over the ASA profile in most refractive outcomes. Keywords: Triple-A, wavefront measurements, corneal aberrations, corneal asphericity, ablation profile

  1. Data Access and Usage Practices Across a Cohort of Researchers at a Large Tertiary Pediatric Hospital: Qualitative Survey Study.

    Science.gov (United States)

    Ho, Hoi Ki Kiki; Görges, Matthias; Portales-Casamar, Elodie

    2018-05-14

    ensuring protection of privacy while achieving efficient data access, research institutions will be able to maximize their research capacity, a crucial step towards achieving the ultimate and shared goal between all stakeholders-to better health outcomes. ©Hoi Ki Kiki Ho, Matthias Görges, Elodie Portales-Casamar. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 14.05.2018.

  2. Placebo controlled, crossover validation study of oral ibuprofen and topical hydrocortisone-21-acetate for a model of ultraviolet B radiation (UVR-induced pain and inflammation

    Directory of Open Access Journals (Sweden)

    Rother M

    2011-10-01

    Full Text Available Matthias Rother, Ilka RotherDepartment of Clinical Operations, X-pert Med GmbH, Graefelfing, GermanyBackground: Pain related to ultraviolet B radiation (UVR induced sunburn is an established, simple, acute pain model. One of the major criticisms is related to the potential dermal adverse events caused by the UVR exposure. This study tried to validate the model for oral and topical drugs and to define the minimum required UVR exposure.Methods: This subject- and observer-blinded, placebo-controlled, crossover study evaluated 600 mg oral ibuprofen (IB and topical hydrocortisone-21-acetate (HC twice daily (bid in 24 healthy volunteers. Treatment started immediately after irradiation and again at 12 hours, 24 hours, and 36 hours post-UVR. Assessment of hyperalgesia to heat and signs of inflammation (erythema, skin temperature for all areas was performed after UVR and again at 6, 12, 24, 36, and 48 hours. Subjects returned within 4–11 days to the study site for the second period of the study. As in the first period, subjects received HC at one side and topical placebo on the other side, but oral treatment was crossed-over.Results: The primary analysis failed to show the expected superiority of the IB-group vs the placebo group in period 1 of the study. Evaluating period 2 alone clearly showed the expected treatment effects of IB for erythema and heat pain threshold. The results were less pronounced for skin temperature. In contrast to IB vs oral placebo, there were no differences in treatment response between HC and topical placebo. UVR at all dosages induced profound erythema and reduction of heat pain threshold without causing blisters or other unexpected discomfort to the subjects. The changes were almost linear between 1 and 2 minimal erythema doses (MED, whereas the change from 2 to 3 MED was less pronounced.Conclusion: Use of 2 MED in upcoming studies seems to be reasonable to limit subjects' UVB exposure. The following procedural changes are

  3. Psychosocial Distress of Patients with Psoriasis: Protocol for an Assessment of Care Needs and the Development of a Supportive Intervention.

    Science.gov (United States)

    Zill, Jördis Maria; Dirmaier, Jörg; Augustin, Matthias; Dwinger, Sarah; Christalle, Eva; Härter, Martin; Mrowietz, Ulrich

    2018-02-07

    Psoriasis is a chronic inflammatory disease that is often associated with a number of somatic and mental comorbidity. Patients with psoriasis show an increased risk of depression and (social) anxiety. The aims of this study are 1) to explore the psychosocial distress of patients with psoriasis and to assess their care needs; and 2) to develop a supportive intervention based on the prior results. A multi-stage design with four phases combining quantitative and qualitative methodology will be used and conducted in two centers. 1) A scoping review and focus groups will be used to design a questionnaire to assess the psychosocial distress and care needs of the patients. 2) The questionnaire developed in phase 1 will be used in a cross-sectional survey to assess the extent of psychosocial distress and supportive care needs in 400 patients with psoriasis. 3) A systematic review and meta-analysis will be conducted to identify psychosocial and psychoeducational interventions for patients with psoriasis and to describe their effectiveness. 4) Based on the results of the phases 2 and 3 a manualized supportive intervention will be developed and the feasibility and acceptance of the intervention will be assessed. Currently, phase 1 of the project has been completed and the recruitment for phase 2 has been started. The systematic review and meta-analysis of phase 3 are conducted simultaneously to phase 2 and results are expected soon. Phase 4 has not been started yet. The expected results of this study will show the extent of psychosocial distress of patients with psoriasis in Germany and supplement previous research with findings about the supportive care needs of this patient group. Moreover, the developed intervention will help to address the psychosocial support needs of patients with psoriasis. Research shows that psychosocial support is strongly needed. ©Jördis Maria Zill, Jörg Dirmaier, Matthias Augustin, Sarah Dwinger, Eva Christalle, Martin Härter, Ulrich Mrowietz

  4. Measuring the importance of health domains in psoriasis – discrete choice experiment versus rating scales

    Directory of Open Access Journals (Sweden)

    Gutknecht M

    2018-03-01

    Full Text Available Mandy Gutknecht,1 Marthe-Lisa Schaarschmidt,1,2 Marion Danner,3 Christine Blome,1 Matthias Augustin1 1German Center for Health Services Research in Dermatology (CVderm, Institute for Health Services Research in Dermatology and Nursing (IVDP, University Medical Center Hamburg-Eppendorf (UKE, Hamburg, Germany; 2Department of Dermatology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany; 3Institute for Health Economics and Clinical Epidemiology (IGKE, University Hospital of Cologne, Cologne, Germany Background: Psoriasis affects different aspects of health-related quality of life (eg, physical, psychological, and social impairments; these health domains can be of different importance for patients. The importance of domains can be measured with the Patient Benefit Index (PBI. This questionnaire weights the achievement of treatment goals by Likert scales (0, “not important at all” to 4, “very important” using the Patient Needs Questionnaire (PNQ. Treatment goals assessed with the PBI have been assigned to five health domains; the importance of each domain can be calculated as the average importance of the respective treatment goals. In this study, the PBI approach of deriving importance weights is contrasted to a discrete choice experiment (DCE, in order to determine the importance of health domains in psoriasis, and to find if the resulting weights will differ when derived from these two methods.Methods: Adult patients with psoriasis completed both questionnaires (PNQ, DCE. The PBI domains were used as attributes in the DCE with the levels “did not help at all”, “helped moderately”, and “helped a lot”.Results: Using DCE, “improving physical functioning” was the most important health domain, followed by “improving psychological well-being”. Using PNQ, these domains were ranked in position two and three following “strengthening confidence in the therapy and in a possible healing”. The latter

  5. Feet swelling in a multistage ultraendurance triathlete: a case study

    Directory of Open Access Journals (Sweden)

    Knechtle B

    2015-10-01

    Full Text Available Beat Knechtle,1 Matthias Alexander Zingg,2 Patrizia Knechtle,1 Thomas Rosemann,2 Christoph Alexander Rüst2 1Gesundheitszentrum St Gallen, St Gallen, 2Institute of Primary Care, University of Zurich, Zurich, Switzerland Abstract: Recent studies investigating ultraendurance athletes showed an association between excessive fluid intake and swelling of the lower limbs such as the feet. To date, this association has been investigated in single-stage ultraendurance races, but not in multistage ultraendurance races. In this case study, we investigated a potential association between fluid intake and feet swelling in a multistage ultraendurance race such as a Deca Iron ultratriathlon with ten Ironman triathlons within 10 consecutive days. A 49-year-old well-experienced ultratriathlete competed in autumn 2013 in the Deca Iron ultratriathlon held in Lonata del Garda, Italy, and finished the race as winner within 129:33 hours:minutes. Changes in body mass (including body fat and lean body mass, foot volume, total body water, and laboratory measurements were assessed. Food and fluid intake during rest and competing were recorded, and energy and fluid turnovers were estimated. During the ten stages, the volume of the feet increased, percentage body fat decreased, creatinine and urea levels increased, hematocrit and hemoglobin values decreased, and plasma [Na+] remained unchanged. The increase in foot volume was significantly and positively related to fluid intake during the stages. The poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. This case report shows that the volume of the foot increased during the ten stages, and the increase in volume was significantly and positively related to fluid intake during the stages. Furthermore, the poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. The continuous feet swelling during the race was

  6. Chronic digitalis therapy in patients before heart transplantation is an independent risk factor for increased posttransplant mortality

    Directory of Open Access Journals (Sweden)

    Rivinius R

    2017-10-01

    Full Text Available Rasmus Rivinius,1 Matthias Helmschrott,1 Arjang Ruhparwar,2 Ann-Kathrin Rahm,1,3 Fabrice F Darche,1 Dierk Thomas,1 Tom Bruckner,4 Philipp Ehlermann,1 Hugo A Katus,1 Andreas O Doesch1,5 1Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, 2Department of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, 3Faculty of Medicine, University of Heidelberg, Heidelberg, 4Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, 5Asklepios Klinik Bad Salzungen GmbH, Department of Pneumology and Oncology, Bad Salzungen, Germany Objectives: Digitalis therapy (digoxin or digitoxin in patients with heart failure is subject to an ongoing debate. Recent data suggest an increased mortality in patients receiving digitalis. This study investigated the effects of chronic digitalis therapy prior to heart transplantation (HTX on posttransplant outcomes.Patients and methods: This was a retrospective, observational, single-center study. It comprised 530 adult patients who were heart-transplanted at Heidelberg University Hospital between 1989 and 2012. Patients with digitalis prior to HTX (≥3 months were compared to those without (no or <3 months of digitalis. Patients with digitalis were further subdivided into patients receiving digoxin or digitoxin. Primary outcomes were early posttransplant atrial fibrillation and mortality.Results: A total of 347 patients (65.5% had digitalis before HTX. Of these, 180 received digoxin (51.9% and 167 received digitoxin (48.1%. Patients with digitalis before HTX had a significantly lower 30-day (P=0.0148 and 2-year (P=0.0473 survival. There was no significant difference between digoxin and digitoxin in 30-day (P=0.9466 or 2-year (P=0.0723 survival. Multivariate analysis for posttransplant 30-day mortality showed pretransplant digitalis therapy as an independent risk factor (hazard ratio =2.097, CI: 1.036–4.248, P=0.0397. Regarding atrial

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    H.L. Peters

    1966-07-01

    Full Text Available - Christoph von Fürer-Haimendorf, Matthias Hermanns, Die religiös-magische weltanschauung der Primitivstämme Indiens. Band I. Die Bhagoria Bhil. Franz Steiner Verlag. Wiesbaden 1964. 543 seiten, 10 Abb., 2 Karten, 26 tafeln. - S.J. Tambiah, S. Arasaratnam, Ceylon. The Modern Nations in Historical Perspective, Robin W. Winks (General Editor Prentice-Hall, Inc. New Jersey 1964. 172 pages. - Mohan K. Gautam, L.P. Vidyarthi, The Maler. A study in nature-man-spirit complex of a hill tribe in Bihar. Foreword by Julian Steward. XVI and 261 pp., with 24 plates, 6 tables, 12 figures, 15 appendices with a glossary of local terms. Calcutta 1963. Bookland Private Ltd. - L. Sluimers, J.M. Halpern, Government, politics and social structure in Laos: A study of tradition and innovation. Wyoming enz., The Cellar Bookshop, 1964. VIII, 197 blz. Southeast Asia Studies, Yale University; Monograph Series No. 4. - P.E. de Josselin de Jong, M.G. Swift, Malay peasant society in Jelebu. L.S.E. Monographs on Social Anthropology no. 29. The Athlone Press, London 1965. 178 pp. - C.H.M. Nooy-Palm, John M. Garvan, The Negritos of the Philippines. Edited by Hermann Hochegger. Wiener Beiträge zur Kulturgeschichte und Linguistik, Band XIV. Verlag Ferdinand Berger, Horn-Wien 1963. 288 pgs., krt. - L.F.B. Dubbeldam, H.L. Peters, Enkele Hoofdstukken uit het sociaal-religieuze leven van een Dani-groep. Diss. 1965 Utrecht, printed by Dagblad voor Noord-Limburg N.V. Venlo. 184 pp., ills. - R. Roolvink, Hans Andreas Poetzelberger, Einführung in das Indonesische. Wiesbaden, 1965. 147 pages, 1 table, 1 map. - P. Voorhoeve, M.D. Wainwright, A guide to western manuscripts and documents in the British Isles relating to South and South East Asia. Compiled by M.D. Wainwright and N. Matthews under the general supervision of J.D. Pearson. London 1965. xix, 352 pp., N. Matthews (eds.

  8. Nail psoriasis as a severity indicator: results from the PsoReal study

    Directory of Open Access Journals (Sweden)

    I Schäfer

    2010-12-01

    Full Text Available Marc A Radtke1, Anna K Langenbruch1, I Schäfer1, Katharina Herberger1, Kristian Reich2, Matthias Augustin11Institute for Health Services Research in Dermatology and Nursing, University Medical Center of Hamburg-Eppendorf, Hamburg; 2Dermatologikum Hamburg, GermanyBackground: Although nail psoriasis affects a substantial proportion of psoriasis patients and causes significant psychologic distress, few epidemiologic data characterizing patients with nail involvement are available. The aim of this research was to elucidate differences between patients with nail psoriasis and those without any nail involvement, taking quality indicators of health care from the patient's perspective into account.Methods: In total, 2449 patient members of the Deutscher Psoriasis Bund, the largest patient organization for psoriasis in Germany, were interviewed in this nationwide, noninterventional, cross-sectional study. Patients with nail psoriasis were compared with patients without any nail involvement with regard to gender, age, disease duration, affected body surface area, health-related quality of life (Dermatology Life Quality Index [DLQI] ED-5D, patient-defined treatment benefit, amount of inpatient treatments, disease duration, and numbers of work days lost.Results: Data from 2449 patients with psoriasis were analyzed. Overall, 44.8% (1078 of patients were female, mean age was 57.0 ± 11.7 years, and 72.8% had nail involvement and showed higher values for affected body surface area than those without nail involvement (8.3% versus 5.6%, respectively; P < 0.004. Health-related quality of life was significantly lower in patients with nail psoriasis (DLQI 7.2 versus 5.3; ED-5D 60.1 versus 67.3, who had more days off work (9.8 versus 3.3.Conclusion: Nail involvement is an important symptom of psoriasis and is associated with greater disease severity and quality of life impairment. Accordingly, management of psoriasis should include a special focus on nail

  9. Analysis of participation and performance in athletes by age group in ultramarathons of more than 200 km in length

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    Zingg MA

    2013-04-01

    Full Text Available Matthias Zingg,1 Beat Knechtle,1,2 Christoph A Rüst,1 Thomas Rosemann,1 Romuald Lepers3 1Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, Switzerland; 3INSERM U1093, Faculty of Sport Sciences, University of Burgundy, Dijon, France Background: Participation and performance trends for athletes by age group have been investigated for marathoners and ultramarathoners competing in races up to 161 km, but not for longer distances of more than 200 km. Methods: Participation and performance trends in athletes by age group in the Badwater (217 km and Spartathlon (246 km races were compared from 2000 to 2012. Results: The number of female and male finishers increased in both races across years (P 0.05. In Spartathlon, the age of the annual five fastest finishers was unchanged at 39.7 ± 2.4 years for men and 44.6 ± 3.2 years for women (P > 0.05. In Badwater, running speed increased in men from 7.9 ± 0.7 km/hour to 8.7 ± 0.6 km/hour (r2 = 0.51, P 0.05. In Badwater, the number of men in age groups 30–34 years (r2 = 0.37, P = 0.03 and 40–44 years (r2 = 0.75, P < 0.01 increased. In Spartathlon, the number of men increased in the age group 40–44 years (r2 = 0.33, P = 0.04. Men in age groups 30–34 (r2 = 0.64, P < 0.01, 35–39 (r2 = 0.33, P = 0.04, 40–44 (r2 = 0.34, P = 0.04, and 55–59 years (r2 = 0.40, P = 0.02 improved running speed in Badwater. In Spartathlon, no change in running speed was observed. Conclusion: The fastest finishers in ultramarathons more than 200 km in distance were 40–45 years old and have to be classified as “master runners” by definition. In contrast to reports of marathoners and ultramarathoners competing in races of 161 km in distance, the increase in participation and the improvement in performance by age group were less pronounced in ultramarathoners competing in races of more than 200 km. Keywords: ultra

  10. Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium, also during ischemia/reperfusion: an ex vivo animal study

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    Chen C

    2016-04-01

    Full Text Available Congcong Chen,1,3 Daniel Chappell,2,3 Thorsten Annecke,2,3 Peter Conzen,2 Matthias Jacob,2,3 Ulrich Welsch,4 Bernhard Zwissler,2 Bernhard F Becker3 1Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; 2Clinic of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany; 3Walter-Brendel-Centre of Experimental Medicine, Ludwig-Maximilians-University, Munich, Germany; 4Institute of Anatomy, Ludwig-Maximilians-University, Munich, Germany Abstract: Glycosaminoglycan hyaluronan (HA, a major constituent of the endothelial glycocalyx, helps to maintain vascular integrity. Preconditioning the heart with volatile anesthetic agents protects against ischemia/reperfusion injury. We investigated a possible protective effect of sevoflurane on the glycocalyx, especially on HA. The effect of pre-ischemic treatment with sevoflurane (15 minutes at 2% vol/vol gas on shedding of HA was evaluated in 28 isolated, beating guinea pig hearts, subjected to warm ischemia (20 minutes at 37°C followed by reperfusion (40 minutes, half with and half without preconditioning by sevoflurane. HA concentration was measured in the coronary effluent. Over the last 20 minutes of reperfusion hydroxyethyl starch (1 g% was continuously infused and the epicardial transudate collected over the last 5 minutes for measuring the colloid extravasation. Additional hearts were fixed by perfusion after the end of reperfusion for immunohistology and electron microscopy. Sevoflurane did not significantly affect post-ischemic oxidative stress, but strongly inhibited shedding of HA during the whole period, surprisingly even prior to ischemia. Immunohistology demonstrated that heparan sulfates and SDC1 of the glycocalyx were also preserved by sevoflurane. Electron microscopy revealed shedding of glycocalyx caused by ischemia and a mostly intact glycocalyx in hearts exposed to sevoflurane. Coronary vascular permeability of the

  11. "Effects of Stress on Decisions Under Uncertainty: A Meta-Analysis": Correction to Starcke and Brand (2016).

    Science.gov (United States)

    2016-09-01

    Reports an error in "Effects of Stress on Decisions Under Uncertainty: A Meta-Analysis" by Katrin Starcke and Matthias Brand ( Psychological Bulletin , Advanced Online Publication, May 23, 2016, np). It should have been reported that the inverted u-shaped relationship between cortisol stress responses and decision-making performance was only observed in female, but not in male participants as suggested by the study by van den Bos, Harteveld, and Stoop (2009). Corrected versions of the affected sentences are provided. (The following abstract of the original article appeared in record 2016-25465-001.) The purpose of the present meta-analysis was to quantify the effects that stress has on decisions made under uncertainty. We hypothesized that stress increases reward seeking and risk taking through alterations of dopamine firing rates and reduces executive control by hindering optimal prefrontal cortex functioning. In certain decision situations, increased reward seeking and risk taking is dysfunctional, whereas in others, this is not the case. We also assumed that the type of stressor plays a role. In addition, moderating variables are analyzed, such as the hormonal stress response, the time between stress onset and decisions, and the participants' age and gender. We included studies in the meta-analysis that investigated decision making after a laboratory stress-induction versus a control condition (k = 32 datasets, N = 1829 participants). A random-effects model revealed that overall, stress conditions lead to decisions that can be described as more disadvantageous, more reward seeking, and more risk taking than nonstress conditions (d = .17). In those situations in which increased reward seeking and risk taking is disadvantageous, stress had significant effects (d = .26), whereas in other situations, no effects were observed (d = .01). Effects were observed under processive stressors (d = .19), but not under systemic ones (d = .09). Moderation analyses did not

  12. Pegaptanib sodium treatment in neovascular age-related macular degeneration: clinical experience in Germany

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    Nikolaus Feucht

    2008-06-01

    Full Text Available Nikolaus Feucht, Huebner Matthias, Chris P Lohmann, Mathias MaierAugenklinik rechts der Isar, Technical University Munich, GermanyBackground: The VEGF Inhibition Study In Ocular Neovascularisation (VISION reported the efficacy of intravitreal (ITV vascular endothelial growth factor (VEGF inhibition with pegaptanib sodium (Macugen® for the treatment of neovascular age-related macular degeneration (AMD. This paper reports clinical experience with pegaptanib sodium for the treatment of occult or minimally classic choroidal neovascularization (CNV due to AMD.Material and methods: The study included 50 eyes (in 49 patients with either occult CNV or minimally classic CNV secondary to neovascular AMD who were not eligible for photodynamic therapy (PDT. Study data were analyzed retrospectively. During the 6-month study, patients were administered an average 2.74 injections of 0.3 mg ITV pegaptanib sodium. Angiography and optical coherence tomography (OCT examinations were carried out and intraocular pressure (IOP and visual acuity (VA were measured at baseline, at 3 months and at 6 months. An eye examination was performed and VA was measured the 2 days following treatment and then again at weeks 4–6, and at 3 and 6 months. OCT, VA, and IOP were also assessed at 1 month.Results: ITV pegaptanib sodium was well tolerated and no treatment complications arose. Mean VA was measured as: 0.37 ± 0.24 at baseline; 0.37 ± 0.25 at 1 month; 0.37 ± 0.25 at 3 months and 0.40 ± 0.26 at 6 months. VA was stabilized in approximately 90% of eyes treated with pegaptanib sodium. OCT examination showed a minimal change in central retinal thickness (CRT during the course of the study, from 251.19 µm at baseline to 251.63 µm at 6 months. No elevation in IOP was measured during treatment at 4–6 months in patients receiving pegaptanib sodium.Conclusions: ITV therapy with pegaptanib sodium for occult and minimally classic CNV secondary to neovascular AMD offered good

  13. Origin and Evolution of the Elements

    Science.gov (United States)

    McWilliam, Andrew; Rauch, Michael

    2004-09-01

    . Chemical composition of the intracluster medium Michael Loewenstein; 28. Quasar elemental abundances and host galaxy evolution Fred Hamann, Matthias Dietrich, Bassem M. Sabra, and Craig Warner; 29. Chemical abundances in the damped Lyα systems Jason X. Prochaska; 30. Intergalactic medium abundances Robert F. Carswell; 31. Conference summary Bernard E. J. Pagel.

  14. The effects of an 8-week multicomponent inpatient treatment program on body composition and anaerobic fitness in overweight and obese children and adolescents

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    Karner-Rezek K

    2013-03-01

    Full Text Available Klaus Karner-Rezek,1 Beat Knechtle,2,3 Matthias Fenzl,4 Christian Schlegel,4 Manuela Konrad,5 Thomas Rosemann2 1Private University of the Principality of Liechtenstein, Triesen, Principality of Liechtenstein, 2Institute of General Practice and for Health Services Research, University of Zurich, Zurich, Switzerland; 3Gesundheitszentrum St Gallen, St Gallen, Switzerland; 4Swiss Olympic Medical Center, Medizinisches Zentrum Bad Ragaz, Switzerland; 5University of Applied Sciences JOANNEUM, Bad Gleichenberg, Austria Background: High intensity exercise is considered as an effective means for reducing body fat. The aims of the present study were to investigate (1 whether body mass would be lost and body composition would change and (2 whether variables of anaerobic fitness prior to the intervention period would be related to loss of body mass and changes in body composition in overweight and obese children and adolescents. Methods: A total of 28 children and adolescents (19 boys, 9 girls attended an 8-week multicomponent inpatient program. Caloric intake was based on the subject's weight and a daily energy deficit of ~500 kcal was targeted. At the beginning and at the end of the program, variables of anaerobic fitness were assessed using Wingate tests. Body composition was measured before and after the program using dual-energy X-ray absorptiometry. Results: Body mass decreased by 11.4% ± 1.6% in boys and by 11.0% ± 2.8% in girls (P < 0.001. Fat mass decreased by 23.8% ± 6.1% in boys and by 21.5% ± 5.2% in girls (P < 0.001. The decrease in fat mass was associated with the decrease in body mass in boys (r = 0.54, P = 0.017 but not in girls (P > 0.05. The decrease in body mass and the decrease in fat mass were neither associated with overall energy expenditure nor with the energy deficit in both genders (P > 0.05. Mean power in W/kg increased in the Wingate tests by 95.4% ± 109.1% in boys and by 100.0% ± 119.9% in girls (P < 0.001. Conclusions

  15. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1968-07-01

    Full Text Available - C. von Fürer-Haimendorf, Bernard Pignède, Les Gurungs. Une population himalayenne du Népal. École pratique des hautes études-Sorbonne. Le monde d’outre-mer passé et présent. Études XXI. Mouton & Co. Paris - La Haye 1966. 414 pp., illustrated. - C. von Fürer-Haimendorf, Matthias Hermanns, Die religiös-magische Weltan-schauung der Primtivstamme Indiens. Band II. Die Bhilala, Korku, Gond, Baiga. Franz Steiner Verlag. Wiesbaden 1966. 571 pages, 70 illustrations, 1 map. - J. Gonda, Vidyanand “Videh”, The exposition of the Vedas, vol. I (translated from Hindi, Veda-Samsthana, Ajmer, India, 1964. 133 p. - J. Gonda, Vidyanand “Videh”, The Vedic prayers, translated from Hindi by B. Bhushan Hajela, Veda-Samsthana, Ajmer, India, 1964. 108 p. - Edmund R. Leach, M. Nash et al., Anthropological Studies in Theravada Buddhism. Yale University: South East Asia Studies. Cultural Report Series No. 13 (1966. xiv, 236 pp., with maps, charts, glossary. - Frank M. le Bar, L.M. Hanks, Ethnographic notes on Northern Thailand. Cornell University Southeast Asia Program. Data Paper No. 58. Ithaca, 1965. xi, 94 pp., maps, tables., J.R. Hanks, Lauriston Sharp (eds. - Lorenz G. Löffler, Lucien Bernot, Les paysans arakanais du Pakistan oriental; l’histoire, le monde végétal et l’organisation sociale des réfugiés Marma (Mog. Le Monde d’Outre-Mer Passé et Présent, lère série: Études XVI, Mouton & Co, Paris-La Haye 1967, 793 pp. (en deux volumes. - C.H.M. Nooy-Palm, Donn V. Hart, Southeast Asian birth customs, three studies in human reproduction. Behavior Science Monographs, Human Relations Area Files Press. New Haven, Connecticut 1965. 303 pp., Phya Anuman Rajadhon, Richard J. Coughlin (eds. - J.W. Minderhout, Charles F. Keyes, Isan: Regionalism in northeastern Thailand. Data Paper: nr. 65, Southeast Asia Program, Department of Asian Studies, Cornell University, Ithaca, New York, March 1967. 86 pp. - J.M. Pluvier, Truong Buu Lam, Patterns of

  16. Magnetic particle imaging: current developments and future directions

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    Panagiotopoulos N

    2015-04-01

    Full Text Available Nikolaos Panagiotopoulos,1 Robert L Duschka,1 Mandy Ahlborg,2 Gael Bringout,2 Christina Debbeler,2 Matthias Graeser,2 Christian Kaethner,2 Kerstin Lüdtke-Buzug,2 Hanne Medimagh,2 Jan Stelzner,2 Thorsten M Buzug,2 Jörg Barkhausen,1 Florian M Vogt,1 Julian Haegele1 1Clinic for Radiology and Nuclear Medicine, University Hospital Schleswig Holstein, Campus Lübeck, 2Institute of Medical Engineering, University of Lübeck, Lübeck, Germany Abstract: Magnetic particle imaging (MPI is a novel imaging method that was first proposed by Gleich and Weizenecker in 2005. Applying static and dynamic magnetic fields, MPI exploits the unique characteristics of superparamagnetic iron oxide nanoparticles (SPIONs. The SPIONs’ response allows a three-dimensional visualization of their distribution in space with a superb contrast, a very high temporal and good spatial resolution. Essentially, it is the SPIONs’ superparamagnetic characteristics, the fact that they are magnetically saturable, and the harmonic composition of the SPIONs’ response that make MPI possible at all. As SPIONs are the essential element of MPI, the development of customized nanoparticles is pursued with the greatest effort by many groups. Their objective is the creation of a SPION or a conglomerate of particles that will feature a much higher MPI performance than nanoparticles currently available commercially. A particle’s MPI performance and suitability is characterized by parameters such as the strength of its MPI signal, its biocompatibility, or its pharmacokinetics. Some of the most important adjuster bolts to tune them are the particles’ iron core and hydrodynamic diameter, their anisotropy, the composition of the particles’ suspension, and their coating. As a three-dimensional, real-time imaging modality that is free of ionizing radiation, MPI appears ideally suited for applications such as vascular imaging and interventions as well as cellular and targeted imaging. A number

  17. Book Reviews

    Directory of Open Access Journals (Sweden)

    Judith Nagata

    1986-04-01

    Full Text Available - Matthias Stiefel, W.F. Wertheim, Matthias Stiefel, Rejoinder to Duller’s review in BKI 142-I, with comments by H.J. Duller., W.F. Wertheim (eds. - K.A. Adelaar, James T. Collins, The historical relationship of the languages of central Maluku, Indonesia, Pacific Linguistics Series D, No. 47, 1983. - J.G. de Casparis, Antoinette M. Barrett Jones, Early tenth-century Java from the inscriptions. A study of economic, social and administrative conditions in the first quarter of the century, Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde No. 107, Dordrecht/Cinnaminson 1984. XI + 204 pp. - P.J. Drooglever, L. de Jong, Het Koninkrijk der Nederlanden in de Tweede Wereldoorlog, deel 11a, Nederlands-Indië I, eerste en tweede helft, Martinus Nijhoff, Leiden 1984, 1199 pp., kaarten, foto’s. - David T. Hill, Julie Southwood, Indonesia: Law, propaganda and terror, with foreword by W.F. Wertheim, Zed press, 1983, 272 pp., Patrick Flanagan (eds. - V.J.H. Houben, C.Ch. van den Haspel, Overwicht in overleg. Hervormingen van justitie, grondgebruik en bestuur in de Vorstenlanden op Java 1880-1930, VKI 111, Dordrecht: Foris publications, 1985. - Maarten Kuitenbrouwer, J. van Goor, Imperialisme in de marge. De afronding van Nederlands-Indië, Utrecht 1985. - Harry A. Poeze, Hansje Galesloot, De Nederlandse vakbondsperiodieken van het IISG; Systematisch overzicht. Amsterdam: Stichting Internationaal Instituut voor Sociale Geschiedenis, 1985, xiv + 241 pp., Tom van der Meer (eds. - Harry A. Poeze, Frits G.P. Jacquet, Sources of the history of Asia and Oceania in the Netherlands. Part II: Sources 1796-1949. München etc.: Saur, 1983, 547 pp. - Harry A. Poeze, Mies Campfens, De Nederlandse archieven van het Internationaal Instituut voor sociale geschiedenis te Amsterdam. Amsterdam: Van Gennep, 1984, 294 pp. - Harry A. Poeze, Henk Hondius, Inventaris van het archief van de Sociaal-Democratische arbeiders partij (SDAP 1894-1946. Amsterdam

  18. JUPITER: Joint Universal Parameter IdenTification and Evaluation of Reliability - An Application Programming Interface (API) for Model Analysis

    Science.gov (United States)

    Banta, Edward R.; Poeter, Eileen P.; Doherty, John E.; Hill, Mary C.

    2006-01-01

    predictions.Use calibration methods to modify parameter values and other aspects of the model.Compare predictions to regulatory limits.Quantify the uncertainty of predictions based on the results of one or many simulations using inferential or Monte Carlo methods.Determine how to manage the system to achieve stated objectives.The capabilities provided by the JUPITER API include, for example, communication with process models, parallel computations, compressed storage of matrices, and flexible input capabilities. The input capabilities use input blocks suitable for lists or arrays of data. The input blocks needed for one application can be included within one data file or distributed among many files. Data exchange between different JUPITER API applications or between applications and other programs is supported by data-exchange files.The JUPITER API has already been used to construct a number of applications. Three simple example applications are presented in this report. More complicated applications include the universal inverse code UCODE_2005 (Poeter et al., 2005), the multi-model analysis MMA (Eileen P. Poeter, Mary C. Hill, E.R. Banta, S.W. Mehl, and Steen Christensen, written commun., 2006), and a code named OPR_PPR (Matthew J. Tonkin, Claire R. Tiedeman, Mary C. Hill, and D. Matthew Ely, written communication, 2006).This report describes a set of underlying organizational concepts and complete specifics about the JUPITER API. While understanding the organizational concept presented is useful to understanding the modules, other organizational concepts can be used in applications constructed using the JUPITER API.

  19. Isotopes in the Arctic atmospheric water cycle

    Science.gov (United States)

    Bonne, Jean-Louis; Werner, Martin; Meyer, Hanno; Kipfstuhl, Sepp; Rabe, Benjamin; Behrens, Melanie; Schönicke, Lutz; Steen Larsen, Hans Christian; Masson-Delmotte, Valérie

    2016-04-01

    measurements highlighted significant synoptic variations in summer in both sites. In Samoylov, the premises of a seasonal cycle have been observed during the summer-fall transition, with a fast humidity level and isotopic decrease. The latitudinal gradient is also highly visible on the Polarstern record. Complementing simulations of the water vapour isotopic composition by the ECHAM5-wiso model reproduce the Polarstern synoptic variability and spatial patterns with a good accuracy. In the near future, our records will be combined with simultaneous water isotope measurements in Iceland (by Hans Christian Steen-Larsen, CIC), Svalbard (by Valérie-Masson Delmotte, LSCE) and paired with complementing climate simulations enhanced by water isotope diagnostics. These data sets, covering an approx. 6,000 km transect of Northern Eurasia will allow for a quantitative assessment of the isotopic variations of the Arctic water cycle. The results of these analyses will also be of relevance for the interpretation of isotope signals found in ice cores and on terrestrial Arctic sites in terms of past climate change.

  20. Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition

    Directory of Open Access Journals (Sweden)

    Waller KL

    2016-01-01

    Full Text Available Katja Linda Waller,1,2 Erik Lykke Mortensen,2,3 Kirsten Avlund,2,3,†, Merete Osler,3,4 Birgitte Fagerlund,5 Martin Lauritzen,2,6 Steen Gammeltoft,7 Poul Jennum1,2 1Danish Center for Sleep Medicine, Clinic of Clinical Neurophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; 2Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; 3Department of Public Health, University of Copenhagen, Copenhagen, Denmark; 4Research Center for Prevention and Health, Rigshospitalet, Glostrup, Denmark; 5Center for Neuropsychiatric Schizophrenia Research (CNSR, Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS, Mental Health Center Glostrup, Glostrup, Denmark; 6Department of Clinical Neurophysiology, Rigshospitalet, Glostrup, Denmark; 7Department of Clinical Biochemistry, Rigshospitalet, Glostrup, Denmark †Kirsten Avlund passed away on June 15, 2012 Abstract: Previous studies have reported an association between circadian disturbances and age-related cognitive impairment. The aim was to study the 24-hour profiles of melatonin and cortisol in relation to cognitive function in middle-aged male subjects. Fifty healthy middle-aged males born in 1953 were recruited from a population-based cohort based on previous cognitive assessments in young adulthood and late midlife. The sample included 24 cognitively high-functioning and 26 cognitively impaired participants. Saliva samples were collected every 4 hours over a 24-hour period and analyzed for cortisol and melatonin levels by immunoassay. All participants exhibited clear circadian rhythms of salivary melatonin and cortisol. Salivary melatonin concentrations had a nocturnal peak at approximately 4 am. The median nocturnal melatonin response at 4 am was significantly lower in the cognitively impaired group than in the high-functioning group (−4.6 pg/mL, 95% CI: −7.84, −1.36, P=0.006. The 24

  1. Applications of a broad-spectrum tool for conservation and fisheries analysis: aquatic gap analysis

    Science.gov (United States)

    McKenna, James E.; Steen, Paul J.; Lyons, John; Stewart, Jana S.

    2009-01-01

    . Aquatic gap analysis naturally focuses on aquatic habitats. The analytical tools are largely based on specification of the species-habitat relations for the system and organism group of interest (Morrison et al. 2003; McKenna et al. 2006; Steen et al. 2006; Sowa et al. 2007). The Great Lakes Regional Aquatic Gap Analysis (GLGap) project focuses primarily on lotic habitat of the U.S. Great Lakes drainage basin and associated states and has been developed to address fish and fisheries issues. These tools are unique because they allow us to address problems at a range of scales from the region to the stream segment and include the ability to predict species specific occurrence or abundance for most of the fish species in the study area. The results and types of questions that can be addressed provide better global understanding of the ecological context within which specific natural resources fit (e.g., neighboring environments and resources, and large and small scale processes). The geographic analysis platform consists of broad and flexible geospatial tools (and associated data) with many potential applications. The objectives of this article are to provide a brief overview of GLGap methods and analysis tools, and demonstrate conservation and planning applications of those data and tools. Although there are many potential applications, we will highlight just three: (1) support for the Eastern Brook Trout Joint Venture (EBTJV), (2) Aquatic Life classification in Wisconsin, and (3) an educational tool that makes use of Google Earth (use of trade or product names does not imply endorsement by the U.S. Government) and Internet accessibility.

  2. Geophysical expression of caldera related volcanism, structures and mineralization in the McDermitt volcanic field

    Science.gov (United States)

    Rytuba, J. J.; Blakely, R. J.; Moring, B.; Miller, R.

    2013-12-01

    The High Rock, Lake Owyhee, and McDermitt volcanic fields, consisting of regionally extensive ash flow tuffs and associated calderas, developed in NW Nevada and SE Oregon following eruption of the ca. 16.7 Ma Steens flood basalt. The first ash flow, the Tuff of Oregon Canyon, erupted from the McDermitt volcanic field at 16.5Ma. It is chemically zoned from peralkaline rhyolite to dacite with trace element ratios that distinguish it from other ash flow tuffs. The source caldera, based on tuff distribution, thickness, and size of lithic fragments, is in the area in which the McDermitt caldera (16.3 Ma) subsequently formed. Gravity and magnetic anomalies are associated with some but not all of the calderas. The White Horse caldera (15.6 Ma), the youngest caldera in the McDermitt volcanic field has the best geophysical expression, with both aeromagnetic and gravity lows coinciding with the caldera. Detailed aeromagnetic and gravity surveys of the McDermitt caldera, combined with geology and radiometric surveys, provides insight into the complexities of caldera collapse, resurgence, post collapse volcanism, and hydrothermal mineralization. The McDermitt caldera is among the most mineralized calderas in the world, whereas other calderas in these three Mid Miocene volcanic fields do not contain important hydrothermal ore deposits, despite having similar age and chemistry. The McDermitt caldera is host to Hg, U, and Li deposits and potentially significant resources of Ga, Sb, and REE. The geophysical data indicate that post-caldera collapse intrusions were important in formation of the hydrothermal systems. An aeromagnetic low along the E caldera margin reflects an intrusion at a depth of 2 km associated with the near-surface McDermitt-hot-spring-type Hg-Sb deposit, and the deeper level, high-sulfidation Ga-REE occurrence. The Li deposits on the W side of the caldera are associated with a series of low amplitude, small diameter aeromagnetic anomalies that form a continuous

  3. New Insights to the Mid Miocene Calc-alkaline Lavas of the Strawberry Volcanics, NE Oregon Surrounded by the Coeval Tholeiitic Columbia River Basalt Province

    Science.gov (United States)

    Steiner, A. R.; Streck, M. J.

    2013-12-01

    intermediate lavas are phenocryst-rich (~25%), containing plagioclase, olivine, and pyroxene. However, phenocrysts in these lavas are strongly zoned and resorbed, and in general, these lavas are volumetrically insignificant compared with the phenocrysts-poor andesites. The CA andesites have olivine Fo #'s that range from 78 to 84 at the cores. Pyroxene Mg #'s range from 41 to 66 near rims and 80 to 84 in the cores. These values mimic the values for of the TH parental basalts of the SV, giving further testament that the CA intermediate lavas were derived from parental TH basalt. Our interpretation of these data is that the SV are the product of hot-spot-related, basaltic magmas interacting with the continental crust. The transition from TH to CA lavas may be generated by the interaction of basaltic lavas of CRBG type with the crustal melts that produced the Strawberry Mountain Rhyolites. Using AFC geochemical modeling, we can show that if we begin with an average Steens basalt composition and introduce the rhyolites, then we can reproduce the observed TH to CA trend. Furthermore, CA andesites (>60% SiO2) have high Fo and Mg #'s (~84), which mimic the TH basaltic lavas of the SV.

  4. Environmental protection congress M-V. Use of regenerative energy sources and hydrogen technology 2010. Proceedings; Klimaschutzkongress M-V. Nutzung regenerativer Energiequellen und Wasserstofftechnik 2010. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Luschtinetz, Thomas; Lehmann, Jochen (eds.)

    2010-07-01

    Within the Environmental Protection Congress M-V from 4th to 6th November, 2010, in Stralsund (Federal Republic of Germany) the following lectures were held: (1) Conception for climate production in Stralsund (Matthias Ahlhaus); (2) Regenerative energies in the power land North Rhine Westfalia (Frank-Michael Baumann); (3) Heat storages - Supporting pillars of the comprehensive utilization of regenerative ideas (Juergen Buehl); (4) Logistics analysis of rice straw for power exploitations and potential green house gas mitigations - An example in Thailand (Mitra Kami Delivand); (5) The Heatpipe-Reformer registered - Development, start-up and testing (Andreas Dengel); (6) The ecological cost of the use of biomass of plants for energy production (Bohdan Deptula); (7) Hydrogen as fuel and energy storage: Strategy and implementation in NIP (Oliver Ehret); (8) The ORGA test: Development of a testing procedure for a practical evaluation of the fermenter biology and NaWaRo biogas plants (Nils Engler); (9) Large scale integration of offshore wind power through wind farm clusters (Alejandro J. Gesino); (10) NANOSITR - Healt, coldness and electricity from one biomass vessel (Bodo Gross); (11) OPTISTRAHL - A two-stage washer unit for biogas (Bodo Gross); (12) Innovation development for renewable energies (Bernward Janzing); (12) Strategic action options for energy supply utilities at renewable energies (Patrick Kemnitz); (13) Hydrogen - An option for a sustainable storage of wind power (Martin Kleimaier); (14) Small parabolic trough power plants - Actual technology and outlook (Joachim Krueger); (15) A photocatalytic generation of hydrogen: Efficient iron-based water reduction catalysts (Sebastian Losse); (16) Environmental assessment of municipal solid waste management in Sri Lanka and India in a life cycle perspective (Samanthi Nirmala M. Menikpura); (17) High temperature low sag conductors in power system with wind power farms (Olgierd Malyszka); (18) Wind

  5. List of Participants

    Science.gov (United States)

    2007-11-01

    Mohab Abou ZeidVrije Universiteit, Brussel Joke AdamKatholieke Universiteit Leuven Nikolas AkerblomMax-Planck-Institut für Physik, München Luis Fernando Alday Utrecht University Stelios Alexandris University of Patras Antonio Amariti Università di Milano-Bicocca Nicola Ambrosetti Université de Neuchâtel Pascal Anastasopoulos Università di Roma Tor Vergata Laura Andrianopoli Enrico Fermi Center Carlo Angelantonj Università di Torino Lilia Anguelova Queen Mary, University of London Daniel AreanUniversidade de Santiago de Compostela Gleb ArutyunovUtrecht University Spyros Avramis NTU Athens—University of Patras Ioannis Bakas University of Patras Subrata Bal Dublin Institute for Advanced Studies Igor Bandos Valencia University Jessica Barrett University of Iceland Marco Baumgartl Eidgenössische Technische Hochschule, Zürich Jacopo Bechi Università di Firenze James Bedford Queen Mary, University of London Jorge Bellorin Universidad Autonoma de Madrid Francesco Benini SISSA, Trieste Eric Bergshoeff Centre for Theoretical Physics, University of Groningen Gaetano BertoldiUniversity of Wales, Swansea Adel Bilal Laboratoire de Physique Théorique, École Normale Superieure, Paris Matthias Blau Université de Neuchâtel Johannes BroedelUniversität Hannover Felix Brümmer Universität Heidelberg Julio Cesar Bueno de Andrade São Paulo State University—UNESP Cliff Burgess McMaster University Agostino Butti Laboratoire de Physique Théorique, École Normale Superieure, Paris Marco Caldarelli Universitat de Barcelona Pablo G Camara Centre de Physique Théorique, École Polytechnique, Palaiseau Joan Camps Universitat de Barcelona Felipe Canoura FernandezUniversidade de Santiago de Compostela Luigi Cappiello Università di Napoli Federico II Luca Carlevaro École Polytechnique, Palaiseau Roberto Casero Centre de Physique Théorique, École Polytechnique, Palaiseau Claudio Caviezel Max-Planck-Institut für Physik, München Alessio Celi Universitat de Barcelona Anna

  6. Stage-dependent prognostic impact of molecular signatures in clear cell renal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Weber T

    2014-05-01

    Full Text Available Thomas Weber,1,2 Matthias Meinhardt,3 Stefan Zastrow,1 Andreas Wienke,4 Kati Erdmann,1 Jörg Hofmann,1 Susanne Fuessel,1 Manfred P Wirth11Department of Urology, Technische Universität Dresden, Dresden, Germany; 2Department of Oncology and Hematology, Martin-Luther-University Halle-Wittenberg, Halle (Saale, Germany; 3Institute of Pathology, Technische Universität Dresden, Dresden, Germany; 4Institute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale, GermanyPurpose: To enhance prognostic information of protein biomarkers for clear cell renal cell carcinomas (ccRCCs, we analyzed them within prognostic groups of ccRCC harboring different tumor characteristics of this clinically and molecularly heterogeneous tumor entity.Methods: Tissue microarrays from 145 patients with primary ccRCC were immunohistochemically analyzed for VHL (von Hippel-Lindau tumor suppressor, Ki67 (marker of proliferation 1, p53 (tumor protein p53, p21 (cyclin-dependent kinase inhibitor 1A, survivin (baculoviral IAP repeat containing 5, and UEA-1 (ulex europaeus agglutinin I to assess microvessel-density.Results: When analyzing all patients, nuclear staining of Ki67 (hazard ratio [HR] 1.08, 95% confidence interval [CI] 1.04–1.12 and nuclear survivin (nS; HR 1.04, 95% CI 1.01–1.08 were significantly associated with disease-specific survival (DSS. In the cohort of patients with advanced localized or metastasized ccRCC, high staining of Ki67, p53 and nS predicted shorter DSS (Ki67: HR 1.07, 95% CI 1.02–1.11; p53: HR 1.05, 95% CI 1.01–1.09; nS: HR 1.08, 95% CI 1.02–1.14. In organ-confined ccRCC, patients with high p21-staining had a longer DSS (HR 0.96, 95% CI 0.92–0.99. In a multivariate model with stepwise backward elimination, tumor size and p21-staining showed a significant association with DSS in patients with "organ-confined" ccRCCs. The p21-staining increased the concordance index of tumor size from

  7. Biogas in agriculture. Status and prospects. Proceedings; Biogas in der Landwirtschaft. Stand und Perspektiven. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    emissions and optimization of the humus balance (Kurt Moeller); (18) Evaluation of greenhouse gases from agricultural biogas plants by means of emission measurements (Jan Liebetrau); (19) Greenhouse gas balances and CO{sub 2}-eq abatement costs of agricultural biogas plants (Ursula Roth); (20) Mixtures of wild plants for production of biogas (Birgit Vollrath); (21) Utilization of straw as a fermentation substrate by means of digestion of straw (Stefan Droege); (22) Biogas from algae, seaweed and seagrass? (Helga Schneider); (23) Common project of farmers and public utilities - Feeding of biogas with amine purification (Johannes Steinhauer); (23) Feeding bio methan from the view of a plant operator (Thomas Balling); (24) Potentials for an optimized and resources carefully delivery of bio methan - Guidelines for a further expansion for biogas utilization (Wolfgang Urban); (25) Repowering of biogas plants (Anton Baumann); (26) Repowering of biogas plants for enhancing the process efficiency (Matthias Effenberger); (27) From troubled kid to star performers - On the repowering of a biogas plant (Hans-Werner Gress). Furthermore, 55 posters were presented.

  8. Preventing Depression in Adults With Subthreshold Depression: Health-Economic Evaluation Alongside a Pragmatic Randomized Controlled Trial of a Web-Based Intervention.

    Science.gov (United States)

    Buntrock, Claudia; Berking, Matthias; Smit, Filip; Lehr, Dirk; Nobis, Stephanie; Riper, Heleen; Cuijpers, Pim; Ebert, David

    2017-01-04

    D and adds that this not only restores health in people with sD, but additionally reduces the risk of developing a MDD. Offering the intervention has an acceptable likelihood of being more cost-effective than enhanced usual care and could therefore reach community members on a wider scale. German Clinical Trials Register: DRKS00004709; http://www.drks.de/DRKS00004709 (Archived by WebCite at http://www.webcitation.org/6kAZVUxy9). ©Claudia Buntrock, Matthias Berking, Filip Smit, Dirk Lehr, Stephanie Nobis, Heleen Riper, Pim Cuijpers, David Ebert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 04.01.2017.

  9. Millennial oscillations in greenland dust and Eurasian Aeolian records - a paleosol-loess perspective (Hans Oeschger Medal Lecture)

    Science.gov (United States)

    Rousseau, Denis-Didier

    2017-04-01

    Greenland ice cores, and a critical study of their source variations, reconciles these records with those observed on the Eurasian continent. This allows demonstrating the link between European and Chinese loess sequences, dust records in Greenland, and variations of the North Atlantic sea ice extent. The sources of the emitted and transported dust material are variable and relate to different environments corresponding to present desert areas in Asia, but also hidden regions related to lower sea level stands, dry rivers, or zones close to the frontal moraines of the main Northern Hemisphere ice sheets in Europe. As a conclusion of this presentation, I address the short term past climatic changes as preserved in the continental eolian records, in line with the Hans Oeschger medal description. Furthermore one can anticipate such study to be at the origin of more sophisticated and elaborated investigations of millennial and sub-millennial continental climate variability on the Northern Hemisphere. The overview presented during this presentation would not have been possible without the help and close collaboration of many colleagues among whom are Niklas BOERS, Adriana SIMA, Anders SVENSSON, Matthias BIGLER, France LAGROIX, Samuel TAYLOR, Pierre ANTOINE, Christine HATTE, Michael GHIL, George KUKLA, Sigfus JOHNSEN, Markus FUCHS, Andreas LANG, Gilles BERGAMETTI, Beatrice MARTICORENA and Ludwig ZOELLER.

  10. Effects of vildagliptin (Galvus® therapy in patients with type 2 diabetes mellitus after heart transplantation

    Directory of Open Access Journals (Sweden)

    Gueler I

    2013-04-01

    Full Text Available Ibrahim Gueler,1 Susanne Mueller,1 Matthias Helmschrott,1 Christian U Oeing,1 Christian Erbel,1 Lutz Frankenstein,1 Christian Gleißner,1 Arjang Ruhparwar,2 Philipp Ehlermann,1 Thomas J Dengler,3 Hugo A Katus,1 Andreas O Doesch1 1Department of Cardiology, University of Heidelberg, Heidelberg, 2Department of Cardiac Surgery, University of Heidelberg, Heidelberg, 3Department of Cardiology, SLK-Kliniken Heilbronn, Bad Friedrichshall, Germany Background: Type 2 Diabetes mellitus (T2DM is a common comorbidity in patients after heart transplantation (HTx and is associated with adverse long-term outcomes. Methods: The retrospective study reported here analyzed the effects of vildagliptin therapy in stable patients post-HTx with T2DM and compared these with control patients for matched-pairs analysis. A total of 30 stable patients post-HTx with T2DM were included in the study. Fifteen patients (mean age 58.6 ± 6.0 years, mean time post-HTx 4.9 ± 5.3 years, twelve male and three female were included in the vildagliptin group (VG and 15 patients were included in the control group (CG (mean age 61.2 ± 8.3 years, mean time post-HTx 7.2 ± 6.6 years, all male. Results: Mean glycated hemoglobin (HbA1c in the VG was 7.4% ± 0.7% before versus 6.8% ± 0.8% after 8 months of vildagliptin therapy (P = 0.002 vs baseline. In the CG, HbA1c was 7.0% ± 0.7% versus 7.3% ± 1.2% at follow-up (P = 0.21. Additionally, there was a significant reduction in mean blood glucose in the VG, from 165.0 ± 18.8 mg/dL to 147.9 ± 22.7 mg/dL (P = 0.002 vs baseline, whereas mean blood glucose increased slightly in the CG from 154.7 ± 19.7 mg/dL to 162.6 ± 35.0 mg/dL (P = 0.21. No statistically significant changes in body weight (from 83.3 ± 10.8 kg to 82.0 ± 10.9 kg, P = 0.20, total cholesterol (1.5%, P = 0.68, or triglyceride levels (8.0%, P = 0.65 were seen in the VG. No significant changes in immunosuppressive drug levels or dosages were observed in either group

  11. Women and the Hanford Site

    Science.gov (United States)

    Gerber, Michele

    2014-03-01

    When we study the technical and scientific history of the Manhattan Project, women's history is sometimes left out. At Hanford, a Site whose past is rich with hard science and heavy construction, it is doubly easy to leave out women's history. After all, at the World War II Hanford Engineer Works - the earliest name for the Hanford Site - only nine percent of the employees were women. None of them were involved in construction, and only one woman was actually involved in the physics and operations of a major facility - Dr. Leona Woods Marshall. She was a physicist present at the startup of B-Reactor, the world's first full-scale nuclear reactor - now a National Historic Landmark. Because her presence was so unique, a special bathroom had to be built for her in B-Reactor. At World War II Hanford, only two women were listed among the nearly 200 members of the top supervisory staff of the prime contractor, and only one regularly attended the staff meetings of the Site commander, Colonel Franklin Matthias. Overall, women comprised less than one percent of the managerial and supervisory staff of the Hanford Engineer Works, most of them were in nursing or on the Recreation Office staff. Almost all of the professional women at Hanford were nurses, and most of the other women of the Hanford Engineer Works were secretaries, clerks, food-service workers, laboratory technicians, messengers, barracks workers, and other support service employees. The one World War II recruiting film made to attract women workers to the Site, that has survived in Site archives, is entitled ``A Day in the Life of a Typical Hanford Girl.'' These historical facts are not mentioned to criticize the past - for it is never wise to apply the standards of one era to another. The Hanford Engineer Works was a 1940s organization, and it functioned by the standards of the 1940s. Just as we cannot criticize the use of asbestos in constructing Hanford (although we may wish they hadn't used so much of it), we

  12. Shaping an Effective Health Information Website on Rare Diseases Using a Group Decision-Making Tool: Inclusion of the Perspectives of Patients, Their Family Members, and Physicians.

    Science.gov (United States)

    Babac, Ana; Litzkendorf, Svenja; Schmidt, Katharina; Pauer, Frédéric; Damm, Kathrin; Frank, Martin; Graf von der Schulenburg, Johann-Matthias

    2017-11-20

    ). Rankings and preference weights were highly heterogeneous. Global ranking positions of patients, family members, and physicians are shown in parentheses, as follows: medical issues (3/4, 4, 4), research (3/4, 2/3, 3), social help offers (1, 2/3, 2), and current events (2, 1, 1); diagnosis (6, 8, 9), therapy (5, 9, 7), general disease pattern (9, 4/5/6, 6), current studies (7, 4/5/6, 3), study results (8, 7, 8), registers (4, 1, 5), psychosocial counseling (1, 2, 4), self-help (3, 3, 2), and sociolegal advice (2, 4/5/6, 1). Differences were verified for patients for 5 information categories (P=.03), physicians for 6 information categories (P=.03), and family members for 4 information categories (P=.04). Our results offer a clear-cut information structure that can transparently translate group decisions into practice. Furthermore, we found different preference structures for rare disease information among patients, family members, and physicians. Some websites already address differences in comprehension between those subgroups. Similar to pharmaceutical companies, health information providers on rare diseases should also acknowledge different information needs to improve the accessibility of information. ©Ana Babac, Svenja Litzkendorf, Katharina Schmidt, Frédéric Pauer, Kathrin Damm, Martin Frank, Johann-Matthias Graf von der Schulenburg. Originally published in the Interactive Journal of Medical Research (http://www.i-jmr.org/), 20.11.2017.

  13. Physical Activity, Sedentary Behavior, and Diet-Related eHealth and mHealth Research: Bibliometric Analysis.

    Science.gov (United States)

    Müller, Andre Matthias; Maher, Carol A; Vandelanotte, Corneel; Hingle, Melanie; Middelweerd, Anouk; Lopez, Michael L; DeSmet, Ann; Short, Camille E; Nathan, Nicole; Hutchesson, Melinda J; Poppe, Louise; Woods, Catherine B; Williams, Susan L; Wark, Petra A

    2018-04-18

    papers originated from high-income countries (96.90%, 1659/1717), in particular the United States (48.83%, 836/1712). Most papers were trials and studied physical activity. Beginning in 2013, research on Generation 2 technologies (eg, smartphones, wearables) sharply increased, while research on Generation 1 (eg, text messages) technologies increased at a reduced pace. Reviews accounted for 20 of the 42 highly-cited papers (n=19 systematic reviews). Social media, smartphone apps, and wearable activity trackers used to encourage physical activity, less sedentary behavior, and/or healthy eating were the focus of 14 highly-cited papers. This study highlighted the rapid growth of the eHealth and mHealth physical activity, sedentary behavior, and diet research field, emphasized the sizeable contribution of research from high-income countries, and pointed to the increased research interest in Generation 2 technologies. It is expected that the field will grow and diversify further and that reviews and research on most recent technologies will continue to strongly impact the field. ©Andre Matthias Müller, Carol A Maher, Corneel Vandelanotte, Melanie Hingle, Anouk Middelweerd, Michael L Lopez, Ann DeSmet, Camille E Short, Nicole Nathan, Melinda J Hutchesson, Louise Poppe, Catherine B Woods, Susan L Williams, Petra A Wark. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.04.2018.

  14. Effectiveness of an Internet- and App-Based Intervention for College Students With Elevated Stress: Randomized Controlled Trial.

    Science.gov (United States)

    Harrer, Mathias; Adam, Sophia Helen; Fleischmann, Rebecca Jessica; Baumeister, Harald; Auerbach, Randy; Bruffaerts, Ronny; Cuijpers, Pim; Kessler, Ronald C; Berking, Matthias; Lehr, Dirk; Ebert, David Daniel

    2018-04-23

    depression. Internet- and mobile-based interventions could be an effective and cost-effective approach to reduce consequences of college-related stress and might potentially attract students with clinically relevant depression who would not otherwise seek help. German Clinical Trial Register DRKS00010212; http://www.drks.de/drks_web/navigate.do? navigationId=trial.HTML&TRIAL_ID=DRKS00010212 (Archived by WebCite at http://www.webcitation.org/6w55Ewhjd). ©Mathias Harrer, Sophia Helen Adam, Rebecca Jessica Fleischmann, Harald Baumeister, Randy Auerbach, Ronny Bruffaerts, Pim Cuijpers, Ronald C Kessler, Matthias Berking, Dirk Lehr, David Daniel Ebert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.04.2018.

  15. Moon-Mars simulation campaign in volcanic Eifel: Remote science support and sample analysis

    Science.gov (United States)

    Offringa, Marloes; Foing, Bernard H.; Kamps, Oscar

    2016-07-01

    assisted by placing the samples onto the sample holder and adjusting test bench settings in order to obtain spectra. After analysis the collected samples were documented and stored by the astronauts, before returning to the base. Points of improvement for the EuroMoonMars2016 analog campaign are the remote control of the computers using an established network between the base and the lander. During following missions the computers should preferably be operated over a larger distance without interference. In the bottom compartment of the lander a rover is stored that in future campaigns could replace astronaut functions by collecting and returning samples, as well as performing adjustments to the analysis test bench by using a remotely controlled robotic arm. Acknowledgements: we thank Dominic Doyle for ESTEC optical lab support, Aidan Cowley (EAC) and Matthias Sperl (DLR) for support discussions, and collaborators from EuroMoonMars Eifel 2015-16 campaign team.

  16. Photoaging Mobile Apps in School-Based Melanoma Prevention: Pilot Study.

    Science.gov (United States)

    Brinker, Titus Josef; Brieske, Christian Martin; Schaefer, Christoph Matthias; Buslaff, Fabian; Gatzka, Martina; Petri, Maximilian Philip; Sondermann, Wiebke; Schadendorf, Dirk; Stoffels, Ingo; Klode, Joachim

    2017-09-08

    (n=74, 71.8% agreement in skin types 1-2 vs n=50, 53.8% agreement in skin types 3-6) and increased use of sun protection (n=70, 68.0% agreement in skin types 1-2 vs n=52, 55.3% agreement in skin types 3-6), and also positively correlated with higher age. We present a novel way of integrating photoaging in school-based melanoma prevention that affects the students' peer group, considers the predictors of UV exposure in accordance with the theory of planned behavior, and is particularly effective in changing behavioral predictors in fair-skinned adolescents (Fitzpatrick skin types 1-2). Further research is required to evaluate the intervention's prospective effects on adolescents of various cultural backgrounds. ©Titus Josef Brinker, Christian Martin Brieske, Christoph Matthias Schaefer, Fabian Buslaff, Martina Gatzka, Maximilian Philip Petri, Wiebke Sondermann, Dirk Schadendorf, Ingo Stoffels, Joachim Klode. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.09.2017.

  17. Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study

    Directory of Open Access Journals (Sweden)

    Kemmler W

    2017-09-01

    Full Text Available Wolfgang Kemmler,1 Anja Weissenfels,1 Marc Teschler,1 Sebastian Willert,1 Michael Bebenek,1 Mahdieh Shojaa,1 Matthias Kohl,2 Ellen Freiberger,3 Cornel Sieber,3 Simon von Stengel1 1Institute of Medical Physics, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany; 2Faculty of Medical and Life Science, University of Furtwangen, Schwenningen, Germany; 3Institute of Biomedicine of Aging, Friedrich-Alexander University of Erlangen-Nürnberg, Nürnberg, Germany Background: Sarcopenic obesity (SO is a geriatric syndrome characterized by the disproportion between the amount of lean mass and fat mass. Exercise decreases fat and maintains muscle mass; however, older people fail to exercise at doses sufficient to affect musculoskeletal and cardiometabolic risk factors. The aim of this study was to evaluate the effect of whole-body electromyostimulation (WB-EMS, a time-efficient, joint-friendly and highly individualized exercise technology, on sarcopenia and SO in older men. Materials and methods: A total of 100 community-dwelling northern Bavarian men aged ≥70 years with sarcopenia and obesity were randomly (1–1–1 assigned to either 16 weeks of 1 WB-EMS and protein supplementation (WB-EMS&P, 2 isolated protein supplementation or 3 nonintervention control. WB-EMS consisted of 1.5×20 min (85 Hz, 350 µs, 4 s of strain to 4 s of rest applied with moderate-to-high intensity while moving. We further generated a daily protein intake of 1.7–1.8 g/kg/body mass per day. The primary study end point was Sarcopenia Z-Score, and the secondary study end points were body fat rate (%, skeletal muscle mass index (SMI and handgrip strength. Results: Intention-to-treat analysis determined a significantly favorable effect of WB-EMS&P (P<0.001 and protein (P=0.007 vs control. Both groups significantly (P<0.001 lost body fat (WB-EMS&P: 2.1%; protein: 1.1% and differed significantly (P≤0.004 from control (0.3%. Differences between WB

  18. Statement at World Cancer Day, 4 February 2013, Vienna, Austria

    International Nuclear Information System (INIS)

    Amano, Y.

    2013-01-01

    Full Text: Good afternoon, Ladies and Gentlemen, I welcome you all to this IAEA event marking World Cancer Day 2013. I am very pleased that we have with us today Professor Kutluk, President-Elect of the Union of International Cancer Control, which initiated World Cancer Day. I also welcome the distinguished Ambassador of Sudan, H.E. Mr. Mahmoud Hassan El Amin, and Dr. Munki Lee, Minister, Permanent Mission of the Republic of Korea, as well as our own Medical Director Dr. Matthias Lademann. Many events are being held around the world today to draw attention to cancer. This year, there is a special focus on dispelling common misconceptions about the disease. One of the most persistent myths about cancer is that it is mainly a disease of wealthy countries. In fact, around 70 percent of cancer deaths occur in developing countries. Another myth is that cancer is invariably a death sentence. In reality, many cancers respond well to treatment and can even be cured. Thanks to early detection and modern treatment methods, millions of men and women now live normal lives for many decades after diagnosis. Often, they die in old age of something other than cancer. Here in Austria, as in all developed countries, we take access to radiotherapy for granted. But the picture is very different in developing countries. It is estimated that there is a shortage of around 5 000 radiotherapy machines in developing countries. That means that millions of people, in Africa and elsewhere, have no access to diagnostic services or treatment. Too many die of conditions that are actually treatable. That is an immense human tragedy. The IAEA Programme of Action for Cancer Therapy - PACT - has been working hard to try to make radiotherapy services available in all countries. Through our Technical Cooperation programme, we are supporting over 130 projects in cancer diagnosis, management and treatment. We help countries to establish oncology and radiotherapy centres. We provide extensive training for

  19. Heliophysics 3 Volume Paperback Set

    Science.gov (United States)

    Schrijver, Carolus J.; Siscoe, George L.

    2013-03-01

    Volume 1: Preface; 1. Prologue Carolus J. Schrijver and George L. Siscoe; 2. Introduction to heliophysics Thomas J. Bogdan; 3. Creation and destruction of magnetic field Matthias Rempel; 4. Magnetic field topology Dana W. Longcope; 5. Magnetic reconnection Terry G. Forbes; 6. Structures of the magnetic field Mark B. Moldwin, George L. Siscoe and Carolus J. Schrijver; 7. Turbulence in space plasmas Charles W. Smith; 8. The solar atmosphere Viggo H. Hansteen; 9. Stellar winds and magnetic fields Viggo H. Hansteen; 10. Fundamentals of planetary magnetospheres Vytenis M. Vasyliunas; 11. Solar-wind magnetosphere coupling: an MHD perspective Frank R. Toffoletto and George L. Siscoe; 12. On the ionosphere and chromosphere Tim Fuller-Rowell and Carolus J. Schrijver; 13. Comparative planetary environments Frances Bagenal; Bibliography; Index. Volume 2: Preface; 1. Perspective on heliophysics George L. Siscoe and Carolus J. Schrijver; 2. Introduction to space storms and radiation Sten Odenwald; 3. In-situ detection of energetic particles George Gloeckler; 4. Radiative signatures of energetic particles Tim Bastian; 5. Observations of solar and stellar eruptions, flares, and jets Hugh Hudson; 6. Models of coronal mass ejections and flares Terry Forbes; 7. Shocks in heliophysics Merav Opher; 8. Particle acceleration in shocks Dietmar Krauss-Varban; 9. Energetic particle transport Joe Giacalone; 10. Energy conversion in planetary magnetospheres Vytenis Vasyliunas; 11. Energization of trapped particles Janet Green; 12. Flares, CMEs, and atmospheric responses Tim Fuller-Rowell and Stanley C. Solomon; 13. Energetic particles and manned spaceflight Stephen Guetersloh and Neal Zapp; 14. Energetic particles and technology Alan Tribble; Appendix I. Authors and editors; List of illustrations; List of tables; Bibliography; Index. Volume 3: Preface; 1. Interconnectedness in heliophysics Carolus J. Schrijver and George L. Siscoe; 2. Long-term evolution of magnetic activity of Sun

  20. Heliophysics 3 Volume Set

    Science.gov (United States)

    Schrijver, Carolus J.; Siscoe, George L.

    2010-11-01

    Volume 1: Preface; 1. Prologue Carolus J. Schrijver and George L. Siscoe; 2. Introduction to heliophysics Thomas J. Bogdan; 3. Creation and destruction of magnetic field Matthias Rempel; 4. Magnetic field topology Dana W. Longcope; 5. Magnetic reconnection Terry G. Forbes; 6. Structures of the magnetic field Mark B. Moldwin, George L. Siscoe and Carolus J. Schrijver; 7. Turbulence in space plasmas Charles W. Smith; 8. The solar atmosphere Viggo H. Hansteen; 9. Stellar winds and magnetic fields Viggo H. Hansteen; 10. Fundamentals of planetary magnetospheres Vytenis M. Vasyliūnas; 11. Solar-wind magnetosphere coupling: an MHD perspective Frank R. Toffoletto and George L. Siscoe; 12. On the ionosphere and chromosphere Tim Fuller-Rowell and Carolus J. Schrijver; 13. Comparative planetary environments Frances Bagenal; Bibliography; Index. Volume 2: Preface; 1. Perspective on heliophysics George L. Siscoe and Carolus J. Schrijver; 2. Introduction to space storms and radiation Sten Odenwald; 3. In-situ detection of energetic particles George Gloeckler; 4. Radiative signatures of energetic particles Tim Bastian; 5. Observations of solar and stellar eruptions, flares, and jets Hugh Hudson; 6. Models of coronal mass ejections and flares Terry Forbes; 7. Shocks in heliophysics Merav Opher; 8. Particle acceleration in shocks Dietmar Krauss-Varban; 9. Energetic particle transport Joe Giacalone; 10. Energy conversion in planetary magnetospheres Vytenis Vasyliūnas; 11. Energization of trapped particles Janet Green; 12. Flares, CMEs, and atmospheric responses Tim Fuller-Rowell and Stanley C. Solomon; 13. Energetic particles and manned spaceflight 358 Stephen Guetersloh and Neal Zapp; 14. Energetic particles and technology Alan Tribble; Appendix I. Authors and editors; List of illustrations; List of tables; Bibliography; Index. Volume 3: Preface; 1. Interconnectedness in heliophysics Carolus J. Schrijver and George L. Siscoe; 2. Long-term evolution of magnetic activity of Sun

  1. Energy for Rhineland-Palatinate. Safety and sustainability as aim for economy, science and policy. 2. rev. ed.; Energie fuer Rheinland-Pfalz. Sicherheit und Nachhaltigkeit als Ziele fuer Wirtschaft, Wissenschaft und Politik

    Energy Technology Data Exchange (ETDEWEB)

    Schaumann, Gunter; Weingarten, Joe (eds.)

    2009-07-01

    - Chances for a worth living and charming Rhineland-Palatinate (Christian Hinsch, Matthias Willenbacher); (19) Energy report Rheinhessen-Nahe - Planning community Rheinhessen-Nahe goes new ways (Jamill Sabbagh); (20) The Donnersberger Energy Concept (DENK) - On the way to energy autonomy and 'Citizen forum energy' (Uwe Welker); (21) Zero-Emission-Village association community Weilerbach: A comprehensive approach for the transformation of renewable energy projects in municipalities (Ottmar Paulus); (22) A good idea of full power: Grimburg gets independent in the case of heat and power (Werner Hitschler); (23) Protection of climate - Reduction of costs - Enhancement of the governmental support and living comfort (Uwe Abel); (24) Spectrum of offers of German offerers of exportable technologies and services for energy efficiency (Stefan Herzog); (25) Technologies for energy efficiency in small and medium-sized companies (Rolf Simon); (26) Power supply and interests of consumers (Hans Weinruter); (27) More energy efficiency in buildings (Michael Coridass); (28) From 3-litre-building to a building without heating costs (Karl Arenz); (28) W.I.N.{sup E} - An efficient heating in great rooms (Christine Kuebler); (29) Utilization of efficient energy and climate protection as a task of the craftsmanship (Guenther Tartter); (30) Enhancement of the energy efficiency by optimizing the building envelope and enhancement of the technical building equipment (Hermann Heinrich, Oliver Rechenbach, Nicole Weyand); (31) The power strategy of the regional company LBB (Stefan Grosshans); (32) Traffic political measures for energy conservation (Gerhard Harmeling); (33) Energy efficiency and alternative drives of future models of Opel (Guenter Schwarz); (34) Energy policy in future radar 2030: Targets and procedure of ZIRP (Joe Weingarten); (35) Energy for Rhineland-Palatinate: Statistical data and diagrams (Sebastian Langguth).

  2. Does canopy mean N concentration explain differences in light use efficiency in 14 eddy-covariance sites?

    Science.gov (United States)

    Peltoniemi, Mikko; Pulkkinen, Minna; Kolari, Pasi; Mäkelä, Annikki

    2010-05-01

    . Mean growing season VPD was the only climatic variable which correlated significantly with the largest actual LUE; none of them correlated with potential LUE. Inclusion of nitrogen in the Prelued-model structure did not improve the goodness of fit of the model. According to our results LUE correlates with mean canopy N concentration. The correlation of mean VPD with the largest actual LUE can also be explained with the model accounting for daily variation in climate, as was made with Prelued-model for the potential LUE. Further studies utilising seasonal values of canopy N are called upon. *Acknowledgements: Eero Nikinmaa, Pertti Hari, Timo Vesala, Tuomas Laurila, Fredrik Lagergren, Meelis Mölder, Anders Lindroth, Thomas Grünwald, Christian Bernhofer, Denis Loustau, Paul Berbigier, Beverly Law, Alison Dunn, Steve Wofsy, Torbjörn Johansson, Torben Christensen, Terry Callaghan, Hans Verbeeck, Remko Duursma, Leonardo Montagnani, Dario Papale, Andreas Ibrom, Ebba Dellwik, Kim Pilegaard, Kentaro Takagi, Eva van Gorsel, Heather Keith, Sonia Wharton, Matthias Falk, Kya Tha Paw U, Matt Schroeder, Jon Lloyd

  3. EDUCATION MANAGEMENT DECISION-MAKERS IN EUROPEAN PRE – UNIVERSITY EDUCATION

    Directory of Open Access Journals (Sweden)

    DUMITRAȘCU DANUȚ DUMITRU

    2012-12-01

    distributed to managers of educational institutions respectively partners with the school Romanian Technical College Matthias Hd. Following the research conducted, the results have shown that due to political differences between countries in European schools are not governed by the same principles regarding the type of autonomy and its extension. In some countries, schools have been granted considerable freedoms, such as in Belgium and the Netherlands. At the other extreme, Spain and France, the transfer of responsibilities was limited. In order to ensure that the information in this study is an accurate representation, questionnaires were distributed to several schools in the countries surveyed. Processed data are related to school year 2010-2011. The data obtained from research can help in better understanding partly the diverse nature of school autonomy policies and models in their takeover by the makers of Romanian school units. The implications of work on management school education are to link the level of autonomy granted and the intensity of monitoring procedures put on the bodies at the school and the staff involved. This study examines the correlation that exists between the degree of autonomy delegated power and the responsibility of school measures that were implemented. The added value of the work lies in the fact that the study focused on several sides of the school management process from the authorities in charge of appointing school managers to autonomy in terms of managerial strategy. Keywords:makers,school autonomy,management body,complete autonomy,school management Cod JEL.:I

  4. Factors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey

    Directory of Open Access Journals (Sweden)

    Price D

    2018-02-01

    Full Text Available David Price,1,2 Dorothy L Keininger,3 Boomi Viswanad,4 Matthias Gasser,5 Susann Walda,5 Florian S Gutzwiller3 1Division of Applied Health Sciences, Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Observational and Pragmatic Research Institute, Singapore; 3Novartis Pharma AG, Basel, Switzerland; 4Novartis Healthcare Pvt. Ltd., Hyderabad, India; 5GfK Switzerland AG, Basel, Switzerland Background: Nonadherence to medication and incorrect use of inhalers represent significant barriers to optimal disease management of patients with chronic obstructive pulmonary disease (COPD. Thus, health care professionals (HCPs play a critical role in educating their patients on appropriate inhaler use and in ensuring medication adherence. However, many patients do not receive appropriate inhaler training or have not had their inhaler technique checked.Methods: The Real-life Experience and Accuracy of inhaLer use (REAL survey was a computer-assisted, telephonic survey consisting of 23 questions gathering real-world information on correct inhaler use, inhalation technique, device attributes, adherence, dosing accuracy, training, correct device use, ease of use, and factors that influence patient adherence in commercially available inhalers delivering COPD maintenance therapy. All results are based on patient-reported data.Results: The survey was conducted between January 4, 2016 and February 2, 2016. A total of 764 patients using various inhalers (Breezhaler® =186; Ellipta® =191; Genuair® =194; Respimat® =201 with mild to very severe COPD, with a mean ± SD age 56±9.8 years, completed the survey. Patient self-reported adherence was significantly lower in younger patients compared to older patients (p=0.020. Eighty-three percent of patients indicated that a demonstration (in-person was “very helpful” versus 58% for video. Patient preferences for training methods were as follows: demonstration of inhaler use (83%, video (58%, instructions for

  5. INTRODUCTION: Physics of Low-dimensional Systems: Nobel Symposium 73

    Science.gov (United States)

    Lundqvist, Stig

    1989-01-01

    Tercentenary Fund of the Bank of Sweden and The Knut and Alice Wallenberg Foundation. Additional support was obtained from the Royal Academy of Sciences, the Nordic Institute for Theoretical Atomic Physics (NORDITA), Chalmers University of Technology and Gothenburg University. To arrange a Nobel Symposium on such hot topics is an open invitation for criticism and trouble. The organizers tried their best to select a few topics of current interest in order to generate a strong interaction between participants and to stimulate a good discussion. I would like to express our apologies to all these prominent scientists who could not be invited because of the small format of the Symposium and the planning of the organizers. These Proceedings contain most of the material presented at the Symposium. A few participants found it inconvenient to prepare a full length paper, which would just have been a modified version of material to appear in regular journals. Others might have felt that a conference proceeding be too slow a medium in comparison with e.g. the New York Times. On the whole however these proceedings give a good report of the science discussed during the Symposium. We would like to place on record our sincere thanks to the participants who contributed substantially in the planning by making valuable suggestions about participants and topics. In particular, Bob Schrieffer did a great job in organizing the programme and effectively to run the Symposium. My co-organizers played a crucial role in the planning and during the Symposium week. Our secretary, Yvonne Steen, deserves our very special thanks for her outstanding work. I would finally like to say something about Gräftåvallen and our hosts, Annica and Tommy Hagström. We decided to take the Symposium out of academia and chose this charming tiny mountain resort on a mountain slope in the northern Swedish mountains about 20 miles from the nearest village. Annica and Tommy Hagström welcomed us with such warm hospitality

  6. INTRODUCTION: The Physics of Chaos and Related Problems: Proceedings of the 59th Nobel Symposium

    Science.gov (United States)

    Lundqvist, Stig

    1985-01-01

    patience with my often rather chaotic actions. Our secretary, Yvonne Steen, deserves very special thanks for her outstanding work for the symposium on top of all her regular duties. I would finally like to say something about Gräftåvallen and our hosts, Annica and Tommy Hagström. We decided to take this symposium out of the cities and away from the academic environment and found this charming tiny mountain resort on a mountain slope in the northern Swedish mountains about 20 miles from the nearest village. Annica and Tommy Hagström welcomed us with such a warm hospitality and offered us throughout the week the best of the local mountain specialities such as reindeer, bear and beaver and a variety of mountain fishes. Also the local community greeted us as some very special guests and arranged an afternoon programme at a nearby shieling with goats, sheep, dairy maids, folk music and folk dancing. They also arranged a wonderful concert in their beautiful church from the 12th century. Altogether it was a very special week also outside the lecture room. We, the organizers, experienced this symposium as an unforgettable scientific event thanks to the outstanding contributions of our participants. We hope that these proceedings will convey to the reader something of the excitement felt by the participants during the symposium week.

  7. BP-C1 in the treatment of patients with stage IV breast cancer: a randomized, double-blind, placebo-controlled multicenter study and an additional open-label treatment phase

    Directory of Open Access Journals (Sweden)

    Larsen S

    2014-11-01

    Full Text Available Stig Larsen,1 Kritiya Butthongkomvong,2 Alexey Manikhas,3 Ekaterina Trishkina,4 Elena Poddubuskaya,5 Marina Matrosova,6 Vichien Srimuninnimit,7 Steen Lindkær-Jensen81Department of Controlled Clinical Trials and Biostatistics, Centre for Epidemiology and Biostatistics, University of Life Science, Oslo, Norway; 2Udonthani Cancer Hospital, Udonthani, Thailand; 3Department of Oncology, City Clinical Oncology, Dispensary, St Petersburg, Russia; 4Department of Oncology, Leningrad Regional Oncology Centre, St Petersburg, Russia; 5Department of Oncology, Unit of Russian Academy of Medical Science, Moscow, Russia; 6Department of Oncology, N Novgorod Regional Oncology Dispensary, Novgorod, Russia; 7Division of Medical Oncology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; 8Department of Surgery and Cancer, Imperial College, Hammersmith Hospital, London, UKAbstract: The aims were to compare the efficacy and tolerability of a new benzene-poly-carboxylic acids complex with cis-diammineplatinum (II dichloride (BP-C1 versus placebo and to investigate the long-term tolerability of BP-C1 in the treatment of patients with metastatic breast cancer.Material and methods: A randomized, double-blind, placebo-controlled multicenter study was performed with a semi-crossover design. Patients allocated to placebo switched to BP-C1 after 32 days of treatment. Patients who completed 32 days of BP-C1 treatment were offered the opportunity to continue on BP-C1 for an additional 32 days in an open-label extension. Patients were then followed up for another 28 days. Thirty patients were given daily intramuscular injections of 0.035 mg/kg of body weight BP-C1 or placebo for 32 days. Biochemistry, hematology, National Cancer Institute Common Terminology Criteria for Adverse Events (CTC-NCI, European Organisation for Research and Treatment of Cancer quality of life questionnaire (QOL-C30 and the breast-cancer–specific BR23 data were recorded at

  8. FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

    Science.gov (United States)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2013-10-01

    Pastorino, DIBE, University of Genoa, Italy Christian Rey, LMT, ENS Cachan, CNRS, France Simon Setzer, Saarland University, Germany Cedric Vonesch, EPFL, Switzerland Local chair Sophie Abriet, SATIE Laboratory, ENS Cachan, France Béatrice Bacquet, SATIE Laboratory, ENS Cachan, France Lydia Matijevic, LMT Laboratory, ENS Cachan France Invited speakers Jérôme Idier, IRCCyN (UMR CNRS 6597), Ecole Centrale de Nantes, France Massimo Fornasier, Faculty of Mathematics, Technical University of Munich, Germany Matthias Fink, Institut Langevin, ESPCI, Université Paris Diderot, France

  9. PREFACE: Ultrathin layers of graphene, h-BN and other honeycomb structures Ultrathin layers of graphene, h-BN and other honeycomb structures

    Science.gov (United States)

    Geber, Thomas; Oshima, Chuhei

    2012-08-01

    nanometer scale. This special section contains interesting papers on graphene, h-BN and related 'honeycomb' compounds on solid surfaces, which are currently in development. Interfacial interaction strongly modifies the electronic and atomic structures of these overlayer systems and substrate surfaces. In addition, one can recognize a variety of growth phenomena by changing the surface and growth conditions, which are promising as regards fabricating those noble nanosystems. We have great pleasure in acknowledging the enthusiastic response and participation of our invited authors and their diligent preparation of the manuscripts. Ultrathin layers of graphene, h-BN and other honeycomb structures contents Ultrathin layers of graphene, h-BN and other honeycomb structuresThomas Geber and Chuhei Oshima Templating of arrays of Ru nanoclusters by monolayer graphene/Ru Moirés with different periodicitiesEli Sutter, Bin Wang, Peter Albrecht, Jayeeta Lahiri, Marie-Laure Bocquet and Peter Sutter Controllable p-doping of graphene on Ir(111) by chlorination with FeCl3N A Vinogradov, K A Simonov, A V Generalov, A S Vinogradov, D V Vyalikh, C Laubschat, N Mårtensson and A B Preobrajenski Optimizing long-range order, band gap, and group velocities for graphene on close-packed metal surfacesF D Natterer, S Rusponi, M Papagno, C Carbone and H Brune Epitaxial growth of graphene on transition metal surfaces: chemical vapor deposition versus liquid phase depositionSamuel Grandthyll, Stefan Gsell, Michael Weinl, Matthias Schreck, Stefan Hüfner and Frank Müller High-yield boron nitride nanosheets from 'chemical blowing': towards practical applications in polymer compositesXuebin Wang, Amir Pakdel, Chunyi Zhi, Kentaro Watanabe, Takashi Sekiguchi, Dmitri Golberg and Yoshio Bando BCx layers with honeycomb lattices on an NbB2(0001) surfaceChuhei Oshima Epitaxial growth of boron-doped graphene by thermal decomposition of B4CWataru Norimatsu, Koichiro Hirata, Yuta Yamamoto, Shigeo Arai and Michiko

  10. PREFACE: Structure and dynamics determined by neutron and x-ray scattering Structure and dynamics determined by neutron and x-ray scattering

    Science.gov (United States)

    Müller-Buschbaum, Peter

    2011-06-01

    structure of pyroxene-type MnGeO3 G J Redhammer, A Senyshyn, G Tippelt and G Roth Nanostructured diblock copolymer films with embedded magnetic nanoparticles Xin Xia, Ezzeldin Metwalli, Matthias A Ruderer, Volker Körstgens, Peter Busch, Peter Böni and Peter Müller-Buschbaum Thermal expansion of a La-based bulk metallic glass: insight from in situ high-energy x-ray diffraction J Bednarcik, S Michalik, M Sikorski, C Curfs, X D Wang, J Z Jiang and H Franz The slow short-time motions of phospholipid molecules with a focus on the influence of multiple scattering and fitting artefacts Sebastian Busch and Tobias Unruh Quasi-elastic scattering under short-range order: the linear regime and beyond Michael Leitner and Gero Vogl Structural relaxation as seen by quasielastic neutron scattering on viscous Zr-Ti-Cu-Ni-Be droplets F Yang, T Kordel, D Holland-Moritz, T Unruh and A Meyer In situ observation of cluster formation during nanoparticle solution casting on a colloidal film S V Roth, G Herzog, V Körstgens, A Buffet, M Schwartzkopf, J Perlich, M M Abul Kashem, R Döhrmann, R Gehrke, A Rothkirch, K Stassig, W Wurth, G Benecke, C Li, P Fratzl, M Rawolle and P Müller-Buschbaum Inelastic neutron and x-ray scattering from incommensurate magnetic systems Peter Böni, Bertrand Roessli and Klaudia Hradil Development of magnetic moments in Fe1-xNix-alloys Benjamin Glaubitz, Stefan Buschhorn, Frank Brüssing, Radu Abrudan and Hartmut Zabel Modified mode-coupling theory for the collective dynamics of simple liquids B Schmid and W Schirmacher Inelastic neutron and low-frequency Raman scattering in niobium-phosphate glasses: the role of spatially fluctuating elastic and elasto-optic constants A Schulte, W Schirmacher, B Schmid and T Unruh The effect of heat treatment on the internal structure of nanostructured block copolymer films A Sepe, E T Hoppe, S Jaksch, D Magerl, Q Zhong, J Perlich, D Posselt, D-M Smilgies and C M Papadakis Hydrogen release from sodium alanate observed by time

  11. N2O and CH4-emissions from energy crops - Can the use of organic fertilizers in form of biogas digestate be considered as a real alternative? Results from a three and a half year multi-site field study of energy crops fertilized with biogas digestate in so

    Science.gov (United States)

    Heintze, Gawan

    2016-04-01

    Gawan Heintze1,2, Matthias Drösler1, Ulrike Hagemann3and Jürgen Augustin3 1University of Applied Sciences Weihenstephan-Triesdorf, Chair of Vegetation Ecology, Weihenstephaner Berg 4, 85354 Freising, Germany 2Technische Universität München, Chair of Plant Nutrition, Emil-Ramann-Str. 2, 85354 Freising, Germany 3Leibniz Centre for Agricultural Landscape Research (ZALF), Eberswalder Straße 84, 15374 Müncheberg, Germany Together with industrial process-related emissions (8.1%) the actual GHG emissions from agriculture (7.5% - 70 million tones (Mt) of carbon dioxide (CO2)-equivalents) representing after energy-related emissions from combustion processes of fossil fuels (83.7%) the second largest budget of the Germany-wide total emissions per year. To reduce the EU's CO2 emissions by 20% by 2020 the cultivation of energy crops for biogas production, ideally coupled to a subsequent return of the resulting residues in form of biogas digestate is intended as one key element in the pathway of renewable energy production. Despite an increasing cultivation of energy crops for the production of biogas aiming to reduce the overall climate impact of the agricultural sector, it is still largely unknown how the application of ammonia-rich organic digestate effects field N2O emissions. Therefore, the collaborative research project "potential for reducing the release of climate-relevant trace gases in the cultivation of energy crops for the production of biogas" was launched. The main objective of the study was to determine an improved process understanding and to quantify the influence of mineral nitrogen fertilization, biogas digestate application, crop type and crop rotation, to gain precise and generalizable statements on the exchange of trace gases like nitrous oxide (N2O) and methane (CH4) on the resulting climate impact. Gas fluxes of N2O and CH4 were measured for three and a half years on two differently managed sites in maize monoculture with different applied organic

  12. PREFACE: Electrostatics 2015

    Science.gov (United States)

    Matthews, James

    2015-10-01

    presentation related to their work. Chilworth Technology and Infolytica both took advantage of this opportunity. David Firth from Chilworth Technology delivered some case studies related to process safety and Chris Emson from Infolytica compared the different types of modelling software used in industry and academia. For two days of the conference, an exhibition was held for delegates to meet and discuss their work with interested companies. Sessions on Modelling and Simulation and on Measurement and Instrumentation were included. Recent successful IOP meetings on Electrospinning and Electrospray prove that this is an important topic, and were the subject of a session in the conference, including an invited talk by Dr Horst von Recum on Electrospun materials for affinity based drug delivery. The conference finished with a session on Environmental and Space Applications. The Southampton Yacht Club provided a fitting venue for the conference dinner on the Wednesday evening. Meal times, and conference dinners in particular, are always a great opportunity to meet with other workers in related fields, and there were many conversations started in question and answer sessions that continued over a plate of food. Within the conference dinner, prizes were awarded for the best student work. Ladislav Konopka's talk in the modelling and simulation session discussed how different particle sizes can be shown to transfer charge in a modelled system. Matthias Perez's poster presented early work on the use of a small-scale wind turbine to generate wind power. The discussions both within the lecture theatre and the ongoing discussions that occur over coffee and tea in between sessions are often a place where new ideas are shared. In fact, the presentation submitted by Dr Atsushi Ohsawa, Charge neutralisation from the side surface of an insulating plate, acknowledged an inspiration from a question raised at a previous Electrostatics conference in Budapest in 2013. In these proceedings the

  13. Über dieses Heft

    Directory of Open Access Journals (Sweden)

    Editors / Herausgeber

    2013-06-01

    Full Text Available Bilder, audiovisuelle Medien, elektronische Medien, World Wide Web: Das Erzählen vollzieht sich mittlerweile in vielfältigen Formen. Der intensive Gebrauch von neuen Medien in unterschiedlichen Zusammenhängen begegnet, überlagert und vermischt sich mit der Rezeption traditioneller literarischer Medien, die nach wie vor weit verbreitet sind. Für die Erzählforschung ergibt sich aus der veränderten kulturellen Praxis eine Vielzahl von Folgen. Die vorliegende Ausgabe von DIEGESIS soll einen Eindruck davon vermitteln. So rückt etwa ein Korpus in den Vordergrund, das lange Zeit eine Randexistenz führte: Erzählungen, die nicht oder nicht ausschließlich durch Sprache vermittelt werden, und solche, die nicht mehr nur die Kulturtechnik des Lesens und Schreibens voraussetzen. Andere Techniken, andere Gesten begleiten den Umgang mit diesen Erzählungen, und diese Differenz wird an denjenigen Stellen besonders deutlich, wo unterschiedliche Medien ineinander verschachtelt sind. Die Erzeugung von Komplexität durch intermediale Relationen charakterisiert dieses neue Korpus und öffnet für die Erzählforschung neue Arbeitsfelder. Gerade die markanten Medienwechsel, die mit der Vermarktung erfolgreicher Stoffe – als Roman, als Film, als Computerspiel, als Comic, als YouTube-Parodie – einhergehen, werfen die doppelte Frage auf, was in diesen Varianten das gemeinsame narrative Substrat, und was hingegen medienspezifische Erzählverfahren sind. Der ersten Perspektive folgt in der vorliegenden Ausgabe Matthias Brütsch mit einer kritischen Prüfung transmedialer Narrativitätsvergleiche; die zweite entfalten Sebastian Armbrusts Beitrag über Komplexität in bekannten Fernsehserien wie House und The Wire und Markus Kuhns Analyse der narrativen Funktion der Handkamera als spezifischem Verfahren in Spielfilmen und fiktionalen Internetclips. Selbstverständlich haben sich auch bestehende Kategorien der Erzählforschung unter dem Eindruck gewandelt, dass

  14. Energy from waste. Vol. 2; Energie aus Abfall. Bd. 2

    Energy Technology Data Exchange (ETDEWEB)

    Thome-Kozmiensky, K.J.; Beckmann, M.

    2007-07-01

    treatment plants with grate firing (Michael Mueck, Werner Hansen, Hans-Peter Alessio); (b) BWV-combustion technology for energy production from waste - a case study: Reno North, line 4. Waste incineration plant with a high effiency (Hans Boegh Andersen); (c) Determination of operational parameters in waste incinerators as a prerequisite for further optimisation (Martin Horeni, Michael Beckmann, Hans Fleischmann, Erhard Barth); (d) Optimization of thermal waste treatment with the INSPECT system by camera based characteristic values and Fuzzy Control (Hubert B. Keller, Joerg Matthes, Holger Schoeenecker, Tristan Krakau); (e) Renewal of process control systems in the waste incineration plant Ruhleben (Thomas Kempin, Henrik Zahn); (f) Fuzzy Control in the waste incineration plant of BSR under consideration of process optimization and economy (Thomas Kempin, Peter Knoop, Henrik Zahn, Christian Gierend). The next chapter 'New plants and extension of plants' contains the following plants: (a) New construction of a waste incinerator in Delfzijl/NL (Matthias Elfers); (b) Replace of waste incinerators at existing sites (Gert Riemenschnieder, Walter Schaefer); (c) Modernisation of the waste-fired cogeneration plant Frankfurt (Gerhard Lohe); (d) Design of plants, supply of fuels and quality control for waste incinerators (Reinhard Schu, Jens Niestroj); (e) Utilization of a water-cooled cooking grate - concept and operating experiences (Werner Auel, Manfred Kuehl); (f) The forward moving combustion grate from Jakob Stiefel GmbH - concept, plants and experiences (Martin Stiefel). The following chapter 'Exhaust gas purification' consists of the following chapters: (a) Does there exist a problem of fine dust or mercury at the waste incineration? (Heidi Foth); (b) Trends in the exhaust gas purification according to the control of the problem of fine dust or mercury - technical solutions (Christoph Mueller, Reiner Stark); (c) Measures and experiments to the reduction of

  15. PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2010)

    Science.gov (United States)

    Lin, Simon C.; Shen, Stella; Neufeld, Niko; Gutsche, Oliver; Cattaneo, Marco; Fisk, Ian; Panzer-Steindel, Bernd; Di Meglio, Alberto; Lokajicek, Milos

    2011-12-01

    & Genoa University/INFN, Switzerland Lothar Bauerdick, Fermilab, USA Ian Bird, CERN, Switzerland Amber Boehnlein, US Department of Energy, USA Kors Bos, CERN, Switzerland Federico Carminati, CERN, Switzerland Philippe Charpentier, CERN, Switzerland Gang Chen, Institute of High Energy Physics, China Peter Clarke, University of Edinburgh, UK Michael Ernst, Brookhaven National Laboratory, USA David Foster, CERN, Switzerland Merino Gonzalo, CIEMAT, Spain John Gordon, STFC-RAL, UK Volker Guelzow, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany John Harvey, CERN, Switzerland Frederic Hemmer, CERN, Switzerland Hafeez Hoorani, NCP, Pakistan Viatcheslav Ilyin, Moscow State University, Russia Matthias Kasemann, DESY, Germany Nobuhiko Katayama, KEK, Japan Milos Lokajícek, FZU Prague, Czech Republic David Malon, ANL, USA Pere Mato Vila, CERN, Switzerland Mirco Mazzucato, INFN CNAF, Italy Richard Mount, SLAC, USA Harvey Newman, Caltech, USA Mitsuaki Nozaki, KEK, Japan Farid Ould-Saada, University of Oslo, Norway Ruth Pordes, Fermilab, USA Hiroshi Sakamoto, The University of Tokyo, Japan Alberto Santoro, UERJ, Brazil Jim Shank, Boston University, USA Alan Silverman, CERN, Switzerland Randy Sobie , University of Victoria, Canada Dongchul Son, Kyungpook National University, South Korea Reda Tafirout , TRIUMF, Canada Victoria White, Fermilab, USA Guy Wormser, LAL, France Frank Wuerthwein, UCSD, USA Charles Young, SLAC, USA

  16. EDITORIAL: Focus on Plasma Medicine

    Science.gov (United States)

    Morfill, G. E.; Kong, M. G.; Zimmermann, J. L.

    2009-11-01

    -pressure microwave plasmas in an N2 and O2 gas mixture M K Singh, A Ogino and M Nagatsu Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma H J Lee, C H Shon, Y S Kim, S Kim, G C Kim and M G Kong The acidification of lipid film surfaces by non-thermal DBD at atmospheric pressure in air A Helmke, D Hoffmeister, N Mertens, S Emmert, J Schuette and W Vioel Reduction and degradation of amyloid aggregates by a pulsed radio-frequency cold atmospheric plasma jet D L Bayliss, J L Walsh, G Shama, F Iza and M G Kong The effect of low-temperature plasma on bacteria as observed by repeated AFM imaging René Pompl, Ferdinand Jamitzky, Tetsuji Shimizu, Bernd Steffes, Wolfram Bunk, Hans-Ulrich Schmidt, Matthias Georgi, Katrin Ramrath, Wilhelm Stolz, Robert W Stark, Takuya Urayama, Shuitsu Fujii and Gregor Eugen Morfill Removal and sterilization of biofilms and planktonic bacteria by microwave-induced argon plasma at atmospheric pressure Mi Hee Lee, Bong Joo Park, Soo Chang Jin, Dohyun Kim, Inho Han, Jungsung Kim, Soon O Hyun, Kie-Hyung Chung and Jong-Chul Park Cell permeabilization using a non-thermal plasma M Leduc, D Guay, R L Leask and S Coulombe Physical and biological mechanisms of direct plasma interaction with living tissue Danil Dobrynin, Gregory Fridman, Gary Friedman and Alexander Fridman Nosocomial infections-a new approach towards preventive medicine using plasmas G E Morfill, T Shimizu, B Steffes and H-U Schmidt Generation and transport mechanisms of chemical species by a post-discharge flow for inactivation of bacteria Takehiko Sato, Shiroh Ochiai and Takuya Urayama Low pressure plasma discharges for the sterilization and decontamination of surfaces F Rossi, O Kylián, H Rauscher, M Hasiwa and D Gilliland Contribution of a portable air plasma torch to rapid blood coagulation as a method of preventing bleeding S P Kuo, O Tarasenko, J Chang, S Popovic, C Y Chen, H W Fan, A Scott, M Lahiani, P Alusta, J D Drake and M Nikolic A two

  17. Influence of soil organic C content on the greenhouse gas emission potential after application of biogas residues or cattle slurry - Results from a pot experiment

    Science.gov (United States)

    Heintze, Gawan

    2017-04-01

    Influence of soil organic C content on the greenhouse gas emission potential after application of biogas residues or cattle slurry - Results from a pot experiment Gawan Heintze1,2, Tim Eickenscheidt1, Urs Schmidthalter2 and Matthias Drösler1 1University of Applied Sciences Weihenstephan-Triesdorf, Chair of Vegetation Ecology, Weihenstephaner Berg 4, 85354 Freising, Germany 2Technische Universität München, Chair of Plant Nutrition, Emil-Ramann-Str. 2, 85354 Freising, Germany The European Union Renewable Energy Directive, which sets a binding target of a final energy consumption of 20% from renewable sources by 2020, has markedly promoted the increase of biogas plants, particularly in Germany. As a consequence, a large amount of biogas residue remains as a by-product of the fermentative process. These residues are now widely used instead of mineral fertilizers or animal slurries to maintain soil fertility and productivity. However, to date, the effect of the application of biogas residue on greenhouse gas (GHG) emission, compared to that of other organic fertilizers, is contradictory in literature, not having been completely understood. It is often stated that GHG fluxes are closely related to the quality of the raw material, particularly the type of soil to which the digestates are applied. This study addresses the questions (a) to what extent are the applications of biogas digestate and cattle slurry different in terms of their GHG emission (CO2, CH4 and N2O) potential, and (b) how do different soil organic carbon contents (SOCs) influence the rate of GHG exchange. We hypothesize that, i) cattle slurry application enhances the CO2 and N2O fluxes compared to the biogas digestate due to the overall higher C and N input, and ii) that with increasing SOC and N content, higher emissions of CO2 and N2O can be expected. The study was conducted as a pot experiment. Biogas digestate and cattle slurry were applied to and incorporated into three different soil types with

  18. PREFACE: Strongly correlated electron systems Strongly correlated electron systems

    Science.gov (United States)

    Saxena, Siddharth S.; Littlewood, P. B.

    2012-07-01

    modulations in the precursor region of FeGeH Wilhelm, M Baenitz, M Schmidt, C Naylor, R Lortz, U K Rößler, A A Leonov and A N Bogdanov Antiferromagnetism in metals: from the cuprate superconductors to the heavy fermion materialsSubir Sachdev, Max A Metlitski and Matthias Punk Superconducting gap structure of the 115s revisitedF Ronning, J-X Zhu, Tanmoy Das, M J Graf, R C Albers, H B Rhee and W E Pickett Nonmagnetic ground states and phase transitions in the caged compounds PrT2Zn20 (T = Ru, Rh and Ir)T Onimaru, K T Matsumoto, N Nagasawa, Y F Inoue, K Umeo, R Tamura, K Nishimoto, S Kittaka, T Sakakibara and T Takabatake New universality class of quantum criticality in Ce- and Yb-based heavy fermionsShinji Watanabe and Kazumasa Miyake

  19. Herbeleving en herinterpretatie. Recente literatuur over Nederland en de Tweede Wereldoorlog

    Directory of Open Access Journals (Sweden)

    P. Romijn

    1987-01-01

    Full Text Available Flehite. Tijdschrift voor verleden en heden van Oost-Utrecht J.R. Pauwels, Bijdragen van het Navorsings- en studiecentrum voor de geschiedenis van de tweede wereldoorlog J. van der Steen, Jaarboek van de Heemkunde 'Roerstreek' H.T. Bussemaker, De militaire spectator Maandorgaan van de documentatiegroep '40-'45 G. Abma, Tussen goed en fout. Nieuwe gezichtspunten in de geschiedschrijving 1940-1945 M. Avesaath-van den Broek, Swalmen '40-'45 P. Baghus, Ontmoeting met de bevrijding. De ouverture in Limburg 1944-1945 P. Berserk, De tweede generatie. Herinneringen van een NSB-kind R. Blatt, Rudy, een strijdbare jood, 1940-1945 H. Bollen, J. Kuiper-Abee, Worsteling om Walcheren 1939-1945 A.H. Bornebroek, De illegaliteit in Twente. Een onderzoek naar het ondergronds georganiseerd verzet in '40-'45 J. Bosdriesz, G. Soeteman, Ons Indië voor de Indonesiërs. De oorlog — de chaos — de vrijheid bewerkt naar de gelijknamige NOS-documentaire door C. van Heekeren F. Boucher, E. Kalkman, D. Schaap, Woord gehouden. Veertig jaar Stichting 1940-1945 B. van der Klaauw, B.M. Rijnhout, De luchtoorlog boven Nederland 1940-1945 A. Korthals Altes, Slag in de schaduw, Peel/Maas 1944-'45 H. Kraaijenbrink, Politierapport 1940-1945. Dagboek van een politieofficier B.H. Laurens, Hun armoede en hun grauwe gezicht. Hongerwinter '44-'45 L. Looijenga, De bevrijding is een jaartal geworden. Noordwolde 1940/45…1985. Een stille omgang door Weststellingwerfs oorlogsgeschiedenis K. Mallan, Als de slag van gisteren… Rotterdam 10-14 mei 1940. De Duitse overrompeling en vernietiging van Nederlands eerste havenstad J.A. Niemeijer, A.J.A. Mulder, Verzet in Groningen J.J. Nortier, Acties in de Archipel. De intelligence-operaties van NEFIS III in de Pacific-oorlog H. Onderwater, Operatie 'Manna'. De geallieerde voedseldroppings april/mei 1945 J. Pisuisse, Dubbelbeeld. Twee vrouwen in oorlogstijd Nederland en Indië R. Roegholt, J. Zwaan, Het verzet 1940-1945 J. Roelfs, De onvergetelijke

  20. List of Participants

    Science.gov (United States)

    2008-11-01

    Mohab Abou ZeidInstitut des Hautes Études Scientifiques, Bures-sur-Yvette Ido AdamMax-Planck-Institut für Gravitationsphysik (AEI), Potsdam Henrik AdorfLeibniz Universität Hannover Mohammad Ali-AkbariIPM, Tehran Antonio Amariti Università di Milano-Bicocca Nicola Ambrosetti Université de Neuchâtel Martin Ammon Max-Planck-Institut für Physik, München Christopher AndreyÉcole Polytechnique Fédérale de Lausanne (EPFL) Laura AndrianopoliPolitecnico di Torino David AndriotLPTHE, Université UPMC Paris VI Carlo Angelantonj Università di Torino Pantelis ApostolopoulosUniversitat de les Illes Balears, Palma Gleb ArutyunovInstitute for Theoretical Physics, Utrecht University Davide AstolfiUniversità di Perugia Spyros AvramisUniversité de Neuchâtel Mirela BabalicChalmers University, Göteborg Foday BahDigicom Ioannis Bakas University of Patras Igor BandosUniversidad de Valencia Jose L F BarbonIFTE UAM/CSIC Madrid Till BargheerMax-Planck-Institut für Gravitationsphysik (AEI), Potsdam Marco Baumgartl Eidgenössische Technische Hochschule (ETH), Zürich James BedfordImperial College London Raphael BenichouLaboratoire de Physique Théorique, École Normale Supérieure, Paris Francesco Benini SISSA, Trieste Eric Bergshoeff Centre for Theoretical Physics, University of Groningen Alice BernamontiVrije Universiteit, Brussel Julia BernardLaboratoire de Physique Théorique, École Normale Supérieure, Paris Adel Bilal Laboratoire de Physique Théorique, École Normale Supérieure, Paris Marco Billo' Università di Torino Matthias Blau Université de Neuchâtel Guillaume BossardAlbert-Einstein-Institut, Golm Leonardo BriziÉcole Polytechnique Fédérale de Lausanne (EPFL) Johannes BroedelLeibniz Universität Hannover (AEI) Tom BrownQueen Mary, University of London Ilka BrunnerEidgenössische Technische Hochschule (ETH), Zürich Erling BrynjolfssonUniversity of Iceland Dmitri BykovSteklov Institute, Moscow and Trinity College, Dublin Joan CampsUniversitat de Barcelona

  1. PREFACE: Complex dynamics of fluids in disordered and crowded environments Complex dynamics of fluids in disordered and crowded environments

    Science.gov (United States)

    Coslovich, Daniele; Kahl, Gerhard; Krakoviack, Vincent

    2011-06-01

    discussions it became evident that the close scientific contact between theory, simulation and experiment brought along a fruitful and mutually inspiring atmosphere. On the theoretical side, these discussions have allowed clarification of several connections between the dynamics of models of fluids in porous media (quenched-annealed, pinned particles models), those of well-known limiting cases (Lorentz gas), of realistic models of liquids with strong dynamic asymmetry (asymmetric size and mass mixtures, sodium silicates, polymers blends) and even of bulk glass-formers. On the experimental side, it appeared that soft matter systems may provide an excellent test-bed to verify the theoretical predictions. From the concluding discussion it was also clear that addressing related issues relevant to biology still remains an open challenge for the future. In view of all this, it was concluded that within a short time period a workshop with analogous scope should be organized to address the progress made on both fundamental and interdisciplinary aspects. The realization of this workshop was made possible by generous financial support from CECAM, Centre Blaise Pascal-ENS de Lyon, and the ESF network 'Molecular Simulations in Biosystems and Material Science' (SimBioMa). Complex dynamics of fluids in disordered and crowded environments contents Phonon dispersions of cluster crystals Tim Neuhaus and Christos N Likos Challenges in determining anomalous diffusion in crowded fluids Marcel Hellmann, Joseph Klafter, Dieter W Heermann and Matthias Weiss Diffusion of active tracers in fluctuating fields David S Dean and Vincent Démery Self-diffusion of non-interacting hard spheres in particle gels Jean-Christophe Gimel and Taco Nicolai Probing glassy states in binary mixtures of soft interpenetrable colloids E Stiakakis, B M Erwin, D Vlassopoulos, M Cloitre, A Munam, M Gauthier, H Iatrou and N Hadjichristidis Fluids with quenched disorder: scaling of the free energy barrier near critical points

  2. PREFACE: XXXth International Colloquium on Group Theoretical Methods in Physics (ICGTMP) (Group30)

    Science.gov (United States)

    Brackx, Fred; De Schepper, Hennie; Van der Jeugt, Joris

    2015-04-01

    participants at the Group30 colloquium from 46 different countries. This high number of participants makes the 30th edition of ICGTMP one of the most successful meetings of the series. We were particularly happy with the attendance of 32 students and many young postdocs: this is promising for the future of the research field and of the colloquium series. The attraction of young scientists was promoted by a reduced participation fee, the availability of cheap accommodation in the University Student Guest House, grants from a US-NSF project and grants from the Organising Committee supporting participants from countries with limited financial resources. The colloquium brought together international top researchers, with a variety of different backgrounds but with "group theoretical or algebraic methods" as common ground. The selection of plenary speakers and topics was made by the Organizing Committee, following the suggestions of the International Advisory Committee (consisting of prominent scientists in their domain), and ensuring the diversity of the subjects treated. There were 11 plenary talks, given as well by distinguished world experts as by young rising stars: Matthias Christandl, Alberto De Sole, Rui Loja Fernandes, François Gay-Balmaz, Gitta Kutyniok, Amiram Leviatan, Karl-Hermann Neeb, Christoph Schweigert, Yuji Tachikawa, Luc Vinet and Joshua Zak. Next to the plenary talks, there were 170 talks in six parallel sessions and 10 poster presentations. All scientific activities took place in the Joseph Plateau Building of the Faculty of Engineering and Architecture of Ghent University, a historical building conveniently located in the city centre of Ghent. In this building we could make use of the main lecture hall (400 seats) for the plenary lectures, six lecture rooms for parallel sessions, two offices for organizational activities and registrations, two PC-rooms and a large foyer for coffee breaks, book exhibitions and the poster session. As part of the colloquium, a

  3. EDITORIAL: Focus on Heart and Mind

    Science.gov (United States)

    Bodenschatz, Eberhard; Wolf, Fred

    2008-01-01

    ädter, I Gerdes and H Engel 'Mind' contributions Eigenanalysis of a neural network for optic flow processing F Weber, H Eichner, H Cuntz and A Borst Time-warp invariant pattern detection with bursting neurons Tim Gollisch Leader neurons in population bursts of 2D living neural networks J-P Eckmann, Shimshon Jacobi, Shimon Marom, Elisha Moses and Cyrille Zbinden Decoding spatiotemporal spike sequences via the finite state automata dynamics of spiking neural networks Dezhe Z Jin Self-organization and the selection of pinwheel density in visual cortical development Matthias Kaschube, Michael Schnabel and Fred Wolf Free association transitions in models of cortical latching dynamics Eleonora Russo, Vijay M K Namboodiri, Alessandro Treves and Emilio Kropff The mechanism of synchronization in feed-forward neuronal networks S Goedeke and M Diesmann On diffusion processes with variable drift rates as models for decision making during learning P Eckhoff, P Holmes, C Law, P M Connolly and J I Gold

  4. Investigating Food and Beverage Industry Market Structure and Market Power Based on Leo and Bresnahan’s Approach

    Directory of Open Access Journals (Sweden)

    M. Nabishahikitash

    2016-03-01

    , Safdarhoseiniet all (2, Mazhari&Yazdani. Yet,foreign studies conducted in this area are varied in different sectors. For example, the studies Angelini&cetorell (15 andRezitis (24 in the banking system can be mentioned.Of the other foreign studies Leo (21, Bresnahan (12, Abayasiri (8, Boyle & Hall (14, Saitone& etal. (25, Koontz (20, Duravall (17, Steen (29, Salhofer and etAl. (28, Allender (10, Siton and et al. (25, Rigoberto et all (22, Lopez & etal. (22, Oustapassidis& etal. (23 can be cited. The model in this paper to estimate market power used for the food and beverage industries has been developed by Bresnahan& Leo. In this model,by considering demand and supply market powercan be investigated. In the next step, marginal cost (cost function is Translog cost and marginal revenue will be obtained. In the final step,by estimatingthe final equation market power can be calculated. The type of industrial classification used in this study is the International Standard Industrial Classification (ISIC. This kind of classification is widely used for empirical studies because of lack of industrial data on the basis of other classifications. We use firm level data aggregated to the4- digit ISIC code of industries. The purpose of this study is to estimate the market structure and market power of the food and drink industry in Iran.For estimating market power, conjectural variation is used. Results and DiscussionIn oligopoly theory, conjectural variation is the belief that one firm has about the way its competitors may react if it varies its output or price. The firm forms a conjecture about the variation in the other firm's output that will accompany any change in its own output. For example, in the classic Cournot model of oligopoly, it is assumed that each firm treats the output of the other firms as given when it chooses its output. This is sometimes called the "Nash conjecture" as it underlies the standard Nash equilibrium concept. However, alternative assumptions can be made

  5. Proceedings of the International Cancer Imaging Society (ICIS 16th Annual Teaching Course

    Directory of Open Access Journals (Sweden)

    Dow-Mu Koh

    2016-10-01

    Full Text Available Table of contents O1 Tumour heterogeneity: what does it mean? Dow-Mu Koh O2 Skeletal sequelae in adult survivors of childhood cancer Sue Creviston Kaste O3 Locoregional effects of breast cancer treatment Sarah J Vinnicombe O4 Imaging of cancer therapy-induced CNS toxicity Giovanni Morana, Andrea Rossi O5 Screening for lung cancer Christian J. Herold O6Risk stratification of lung nodules Theresa C. McLoud O7 PET imaging of pulmonary nodules Kirk A Frey O8 Transarterial tumour therapy Bernhard Gebauer O9 Interventional radiology in paediatric oncology Derek Roebuck O10 Image guided prostate interventions Jurgen J. Fütterer O11 Imaging cancer predisposition syndromes Alexander J. Towbin O12Chest and chest wall masses Thierry AG Huisman O13 Abdominal masses: good or bad? Anne MJB Smets O14 Hepatobiliary MR contrast: enhanced liver MRI for HCC diagnosis and management Giovanni Morana O15 Role of US elastography and multimodality fusion for managing patients with chronic liver disease and HCC Jeong Min Lee O16 Opportunities and challenges in imaging metastatic disease Hersh Chandarana O17 Diagnosis, treatment monitoring, and follow-up of lymphoma Marius E. Mayerhoefer, Markus Raderer, Alexander Haug O18 Managing high-risk and advanced prostate cancer Matthias Eiber O19 Immunotherapy: imaging challenges Bernhard Gebauer O20 RECIST and RECIST 1.1 Andrea Rockall O21 Challenges of RECIST in oncology imaging basics for the trainee and novice Aslam Sohaib O22 Lymphoma: PET for interim and end of treatment response assessment: a users’ guide to the Deauville Score Victoria S Warbey O23 Available resources Hebert Alberto Vargas O24 ICIS e-portal and the online learning community Dow-Mu Koh O25 Benign lesions that mimic pancreatic cancer Jay P Heiken O26 Staging and reporting pancreatic malignancies Isaac R Francis, Mahmoud, M Al-Hawary, Ravi K Kaza O27 Intraductal papillary mucinous neoplasm Giovanni Morana O28 Cystic pancreatic tumours Mirko D’Onofrio O

  6. Preface: Introductory Remarks: Linear Scaling Methods

    Science.gov (United States)

    Bowler, D. R.; Fattebert, J.-L.; Gillan, M. J.; Haynes, P. D.; Skylaris, C.-K.

    2008-07-01

    Haynes, Chris-Kriton Skylaris, Arash Mostofi and Mike Payne A miscellaneous overview of SIESTA algorithms Jose M Soler Wavelets as a basis set for electronic structure calculations and electrostatic problems Stefan Goedecker Wavelets as a basis set for linear scaling electronic structure calculationsMark Rayson O(N) Krylov subspace method for large-scale ab initio electronic structure calculations Taisuke Ozaki Linear scaling calculations with the divide-and-conquer approach and with non-orthogonal localized orbitals Weitao Yang Toward efficient wavefunction based linear scaling energy minimization Valery Weber Accurate O(N) first-principles DFT calculations using finite differences and confined orbitals Jean-Luc Fattebert Linear-scaling methods in dynamics simulations or beyond DFT and ground state properties An O(N) time-domain algorithm for TDDFT Guan Hua Chen Local correlation theory and electronic delocalization Joseph Subotnik Ab initio molecular dynamics with linear scaling: foundations and applications Eiji Tsuchida Towards a linear scaling Car-Parrinello-like approach to Born-Oppenheimer molecular dynamics Thomas Kühne, Michele Ceriotti, Matthias Krack and Michele Parrinello Partial linear scaling for quantum Monte Carlo calculations on condensed matter Mike Gillan Exact embedding of local defects in crystals using maximally localized Wannier functions Eric Cancès Faster GW calculations in larger model structures using ultralocalized nonorthogonal Wannier functions Paolo Umari Other approaches for linear-scaling, including methods formetals Partition-of-unity finite element method for large, accurate electronic-structure calculations of metals John E Pask and Natarajan Sukumar Semiclassical approach to density functional theory Kieron Burke Ab initio transport calculations in defected carbon nanotubes using O(N) techniques Blanca Biel, F J Garcia-Vidal, A Rubio and F Flores Large-scale calculations with the tight-binding (screened) KKR method Rudolf Zeller

  7. Editorial: Computerspiele und Videogames in formellen und informellen Bildungskontexten

    Directory of Open Access Journals (Sweden)

    Johannes Fromme

    2008-01-01

    Serious Games» oder auch «Game-based Learning» geführt werden (Petko; Bopp; Berger/Marbach; Lampert/Schwinge/Tolks; Malo/Neudorf/Wist; Pfannstiel/Sänger/Schmidt. Daneben widmen sich Beiträge der Frage, wie die Lern- und Bildungsrelevanz der medial-kulturellen Praxen, die sich weitgehend unabhängig von pädagogischer Intervention entfalten, untersucht und verstanden, aber auch pädagogisch unterstützt werden können (Fromme/Jörissen/Unger; Schrammel/Mitgutsch. In einem Beitrag geht es schliesslich darum, Computerspiele selbst zum Gegenstand der pädagogischen Reflexion machen (Biermann. Diese Verteilung spiegelt das Gewicht der Schwerpunkte innerhalb des aktuellen Diskurses über den Zusammenhang von Computerspielen und Lernen/Bildung durchaus angemessen wider. Dominik Petko fokussiert auf formelle Lern- und Bildungskontexte und behandelt die Frage, welche didaktischen Potenziale Computerspiele für den gezielten Einsatz in Schule und Ausbildung aufweisen. Ausgangspunkt ist die Überlegung, dass es für den schulischen Bereich nicht ausreicht, die allgemeinen Lernpotenziale der Spiele auszuweisen und die Muster des spielimmanenten Lernens nachzuzeichnen, wie dies in einigen Publikationen der letzten Jahre geschehe. Um einen Schritt weiterzukommen und zu erreichen, dass digitale Spiele tatsächlich vermehrt in den Unterricht integriert werden, komme es darauf an, den Lehrpersonen zu zeigen, dass der Einsatz solcher Spiele einerseits mit einem vertretbaren Aufwand möglich ist und andererseits zu einem erkenn- und begründbaren Mehrwert führt. Dazu sei im ersten Schritt eine genauere Analyse und Typisierung der Spiele und anschliessend eine Konkretisierung der didaktischen Strategien und Arrangements für die sinnvolle Einbettung in den Unterricht erforderlich. Der Beitrag vermittelt einen ersten systematischen Überblick über entsprechende mediendidaktische Ziele und Ansätze für den Einsatz von Computerspielen in Schule und Unterricht. Matthias Bopp geht aus von der

  8. EDITORIAL: Colloidal suspensions Colloidal suspensions

    Science.gov (United States)

    Petukhov, Andrei; Kegel, Willem; van Duijneveldt, Jeroen

    2011-05-01

    N W 2002 Nature 416 811 [9] Borsboom M et al 1998 J. Synchrotron Radiat. 5 518 [10] Zernike F and Prins J A 1927 Z. Phys. 41 184 Colloidal suspensions contents How much does the core structure of a three-phase contact line contribute to the line tension near a wetting transition? J O Indekeu, K Koga and B Widom A systematic coarse-graining strategy for semi-dilute copolymer solutions: from monomers to micelles Barbara Capone, Ivan Coluzza and Jean-Pierre Hansen Structural searches using isopointal sets as generators: densest packings for binary hard sphere mixtures Toby S Hudson and Peter Harrowell The theory of delamination during drying of confined colloidal suspensions K J Wallenstein and W B Russel Electrostatics Modeling of equilibrium hollow objects stabilized by electrostatics Ethayaraja Mani, Jan Groenewold and Willem K Kegel The Donnan equilibrium: I. On the thermodynamic foundation of the Donnan equation of state A Philipse and A Vrij Colloidal rods and platelets Cholesteric order in systems of helical Yukawa rods H H Wensink and G Jackson Magnetic-field-induced nematic-nematic phase separation and droplet formation in colloidal goethite E van den Pol, A A Verhoeff, A Lupascu, M A Diaconeasa, P Davidson, I Dozov, B W M Kuipers, D M E Thies-Weesie and G J Vroege Structure of colloidal sphere-plate mixtures N Doshi, G Cinacchi, J S van Duijneveldt, T Cosgrove, S W Prescott, I Grillo, J Phipps and D I Gittins 3D structure of nematic and columnar phases of hard colloidal platelets A B G M Leferink op Reinink, J M Meijer, D Kleshchanok, D V Byelov, G J Vroege, A V Petukhov and H N W Lekkerkerker Phase behaviour of binary mixtures of diamagnetic colloidal platelets in an external magnetic field Jonathan Phillips and Matthias Schmidt Rheo-SAXS investigation of shear-thinning behaviour of very anisometric repulsive disc-like clay suspensions A M Philippe, C Baravian, M Imperor-Clerc, J De Silva, E Paineau, I Bihannic, P Davidson, F Meneau, P Levitz and L J Michot

  9. AAS 227: Day 4

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    University of Wisconsin-Madison. Bechtol spoke about the recent discovery of new satellite galaxies of the Milky Way. Dwarf galaxies orbiting the Milky Way are often hard to spot because they are so faint while globular clusters have mass-to-light ratios of around 1, the ultra-faint satellites around the Milky Way can have mass-to-light ratios of hundreds or thousands! A combination of better facilities and improved analysis techniques has been lengthening the list of known Milky Way satellites, however: SDSS took us from ~10 to ~30 in the last ten years, and facilities like the Dark Energy Survey Camera (DES), Pan-STARRS 1, SkyMapper, and Hyper Suprime-Cam pushed that number to ~50 in 2015.Bechtol plenary on the discovery of new MW satellites #aas227 pic.twitter.com/3GH0Sd2J8c Matthias Steinmetz (@GalacticRAVE) January 8, 2016The new candidates discovered with DES are all less luminous and more distant than previous satellites found. One interesting aspect of this sample is that 15/17 of the candidates fall in the southern half of the DES footprint, and are located near the Large and Small Magellanic Clouds. This anisotropy is not thought to be a selection effect so is it coincidence, or could they possibly be satellites of satellites? Were not sure yet!Why do we care about finding Milky Way satellites? There are lots of reasons, but one of the biggest is that they may help us to unravel some of the mysteries of dark matter. These faint-but-massive galaxies were probably born in the Milky Ways dark-matter halo, and they could be great places to indirectly detect dark matter. In addition, theres the missing satellite problem the phenomenon wherein the cold-dark-matter model predicts there should be hundreds of satellites around the Milky Way, yet weve only found a few dozen. Finding more of these galaxies would help clear up whether its the theory or the observations that are wrong.One more time, it shouldnt be called the Missing Satellite Problem. The theorists have a

  10. EDITORIAL: Colloidal dispersions in external fields Colloidal dispersions in external fields

    Science.gov (United States)

    Löwen, Hartmut

    2012-11-01

    ller, Bastian Sieber, Holger Schweinfurth, Holger Reiber and Gerhard Nägele Electrokinetics on superhydrophobic surfacesPeriklis Papadopoulos, Xu Deng, Doris Vollmer and Hans-Jürgen Butt Numerical electrokineticsR Schmitz and B Dünweg Dielectric response of nanoscopic spherical colloids in alternating electric fields: a dissipative particle dynamics simulationJiajia Zhou and Friederike Schmid Self-assembly of colloidal particles into strings in a homogeneous external electric or magnetic fieldFrank Smallenburg, Hanumantha Rao Vutukuri, Arnout Imhof, Alfons van Blaaderen and Marjolein Dijkstra The nature of the laning transition in two dimensionsT Glanz and H Löwen Microscopic theory for anisotropic pair correlations in driven binary mixturesMatthias Kohl, Alexei V Ivlev, Philip Brandt, Gregor E Morfill and Hartmut Löwen Dynamics of individual colloidal particles in one-dimensional random potentials: a simulation studyRichard D L Hanes and Stefan U Egelhaaf An interacting dipole model to explore broadband transverse optical bindingMichael Mazilu, Andrew Rudhall, Ewan M Wright and Kishan Dholakia Comparison of 2D melting criteria in a colloidal systemPatrick Dillmann, Georg Maret and Peter Keim Effects of confinement and external fields on structure and transport in colloidal dispersions in reduced dimensionalityD Wilms, S Deutschländer, U Siems, K Franzrahe, P Henseler, P Keim, N Schwierz, P Virnau, K Binder, G Maret and P Nielaba Stochastic transport of particles across single barriersChristian Kreuter, Ullrich Siems, Peter Henseler, Peter Nielaba, Paul Leiderer and Artur Erbe A perspective on the interfacial properties of nanoscopic liquid dropsAlexandr Malijevský and George Jackson Controlling the wetting properties of the Asakura-Oosawa model and applications to spherical confinementA Statt, A Winkler, P Virnau and K Binder Crystalline multilayers of charged colloids in soft confinement: experiment versus theoryE C Oğuz, A Reinmüller, H J Schöpe, T Palberg, R

  11. SINFONI Opens with Upbeat Chords

    Science.gov (United States)

    2004-08-01

    the development of SINFONI for nearly 7 years. Some of the members of the Commissioning Teams are depicted in PR Photos 24g/04 and 24h/04; in addition to the SPIFFI team members present on the second photo, Walter Bornemann, Reinhard Genzel, Hans Gemperlein, Stefan Huber have also been working on the reintegration/commissioning in Paranal. Notes [1] This press release is issued in coordination between ESO, the Max-Planck-Institute for Extraterrestrial Physics (MPE) in Garching, Germany, and the Nederlandse Onderzoekschool Voor Astronomie in Leiden, The Netherlands. A German version is available at http://www.mpg.de/bilderBerichteDokumente/dokumentation/pressemitteilungen/2004/pressemitteilung20040824/index.html and a Dutch version at http://www.astronomy.nl/inhoud/pers/persberichten/30_08_04.html. [2] The SINFONI team consists of Roberto Abuter, Andrew Baker, Walter Bornemann, Ric Davies, Frank Eisenhauer (SPIFFI Principal Investigator), Hans Gemperlein, Reinhard Genzel (MPE Director), Andrea Gilbert, Armin Goldbrunner, Matthew Horrobin, Stefan Huber, Christof Iserlohe, Matthew Lehnert, Werner Lieb, Dieter Lutz, Nicole Nesvadba, Claudia Röhrle, Jürgen Schreiber, Linda Tacconi, Matthias Tecza, Niranjan Thatte, Harald Weisz (Max-Planck-Institut für Extraterrestrische Physik, Garching, Germany), Anthony Brown, Paul van der Werf (NOVA, Leiden, The Netherlands), Eddy Elswijk, Johan Pragt, Jan Kragt, Gabby Kroes, Ton Schoenmaker, Rik ter Horst (ASTRON, Dwingeloo, The Netherlands), Henri Bonnet (SINFONI Project Manager), Roberto Castillo, Ralf Conzelmann, Romuald Damster, Bernard Delabre, Christophe Dupuy, Robert Donaldson, Christophe Dumas, Enrico Fedrigo, Gert Finger, Gordon Gillet, Norbert Hubin (Head of Adaptive Optics Dept.), Andreas Kaufer, Franz Koch, Johann Kolb, Andrea Modigliani, Guy Monnet (Head of Telescope Systems Division), Chris Lidman, Jochen Liske, Jean Louis Lizon, Markus Kissler-Patig (SINFONI Instrument Scientist), Jerome Paufique, Juha Reunanen