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Sample records for marsha riddle buly

  1. Riddle in preschool education

    OpenAIRE

    Ferjančič, Tanja

    2016-01-01

    In this work, in theoretical part, I would like to explore and present: (1) the theory of riddle and forms in which it appears; (2) the historical origin of riddles; (3) the emergence of the first riddles in Slovenia; (4) the characteristics of literary riddles and definition how riddles are formed; (5) the importance of the riddles in the preschool period, since most of them are for younger generation; (6) different ways of setting and solving riddles with the youngest according to their abi...

  2. Unfolding the Riddling Bifurcation

    DEFF Research Database (Denmark)

    Maistrenko, Yu.; Popovych, O.; Mosekilde, Erik

    1999-01-01

    We present analytical conditions for the riddling bifurcation in a system of two symmetrically coupled, identical, smooth one-dimensional maps to be soft or hard and describe a generic scenario for the transformations of the basin of attraction following a soft riddling bifurcation.......We present analytical conditions for the riddling bifurcation in a system of two symmetrically coupled, identical, smooth one-dimensional maps to be soft or hard and describe a generic scenario for the transformations of the basin of attraction following a soft riddling bifurcation....

  3. Noise-Induced Riddling in Chaotic Systems

    International Nuclear Information System (INIS)

    Lai, Y.; Grebogi, C.

    1996-01-01

    Recent works have considered the situation of riddling where, when a chaotic attractor lying in an invariant subspace is transversely stable, the basin of the attractor can be riddled with holes that belong to the basin of another attractor. We show that riddling can be induced by arbitrarily small random noise even if the attractor is transversely unstable, and we obtain universal scaling laws for noise-induced riddling. Our results imply that the phenomenon of riddling can be more prevalent than expected before, as noise is practically inevitable in dynamical systems. copyright 1996 The American Physical Society

  4. The Riddle of the Smart Machines

    Science.gov (United States)

    Howell, Dusti D.

    2010-01-01

    Hundreds of graduate students were introduced to the fields of instructional design and educational technology with the riddle of the smart machines, yet over the years no one has answered it correctly. After revealing the surprising answer to this riddle, both the negative and positive impacts of smart machines are analyzed. An example of this is…

  5. Riddle Hero: Play and Poetry in the Exeter Book Riddles

    Science.gov (United States)

    Higl, Andrew

    2017-01-01

    The author discusses the Exeter Book riddles, some of the earliest poems in English, specifically Old English, as perfect examples of how play and poetry intersect. Their playfulness, he claims, is most apparent in the original manuscript, but notes that few modern readers read Old English. The orthography of the manuscript also helps to make the…

  6. Biosemiotic Cosmogony of the Riddle of Life!

    DEFF Research Database (Denmark)

    Brier, Søren

    2016-01-01

    Review of Vinicius, R. and Fernández, E. (Eds.) (2014): Peirce and Biosemiotics: A Guess at the Riddle of life, New York: Springer. Biosemiotics Books no. 11. ISBN 978-94-007-7732-3, USD $189.......Review of Vinicius, R. and Fernández, E. (Eds.) (2014): Peirce and Biosemiotics: A Guess at the Riddle of life, New York: Springer. Biosemiotics Books no. 11. ISBN 978-94-007-7732-3, USD $189....

  7. Riddling bifurcation and interstellar journeys

    International Nuclear Information System (INIS)

    Kapitaniak, Tomasz

    2005-01-01

    We show that riddling bifurcation which is characteristic for low-dimensional attractors embedded in higher-dimensional phase space can give physical mechanism explaining interstellar journeys described in science-fiction literature

  8. Ability to solve riddles in patients with speech and language impairments after stroke.

    Science.gov (United States)

    Savić, Goran

    2016-01-01

    Successful riddle solving requires recognition of the meaning of words, attention, concentration, memory, connectivity and analysis of riddle content, and sufficiently developed associative thinking. The aim of the study was to determine the ability to solve riddles in stroke patients who do or do not have speech and language disorders (SLDs), to determine the presence of SLDs in relation to the lesion localization, as well as to define the relationship between riddle-solving and functional impairment of a body side. The sample consisted of 88 patients. The data used included age, sex, educational level, time of stroke onset, presence of an SLD, lesion localization, and functional damage of the body side. The patients were presented with a task of solving 10 riddles. A significant SLD was present in 38.60% of the patients. Brain lesions were found distributed at 46 different brain sites. Patients with different lesion localization had different success in solving riddles. Patients with perisylvian cortex brain lesions, or patients with Wernicke and global aphasia, had the poorest results. The group with SLDs had an average success of solved riddles of 26.76% (p = 0.000). The group with right-sided functional impairments had average success of 37.14%, and the group with functional impairments of the left side of the body 56.88% (p = 0.002). Most patients with SLDs had a low ability of solving riddles. Most of the patients with left brain lesions and perisylvian cortex damage demonstrated lower ability in solving riddles in relation to patients with right hemisphere lesions.

  9. Ability to solve riddles in patients with speech and language impairments after stroke

    Directory of Open Access Journals (Sweden)

    Savić Goran

    2016-01-01

    Full Text Available Introduction. Successful riddle solving requires recognition of the meaning of words, attention, concentration, memory, connectivity and analysis of riddle content, and sufficiently developed associative thinking. Objective. The aim of the study was to determine the ability to solve riddles in stroke patients who do or do not have speech and language disorders (SLDs, to determine the presence of SLDs in relation to the lesion localization, as well as to define the relationship between riddle-solving and functional impairment of a body side. Methods. The sample consisted of 88 patients. The data used included age, sex, educational level, time of stroke onset, presence of an SLD, lesion localization, and functional damage of the body side. The patients were presented with a task of solving 10 riddles. Results. A significant SLD was present in 38.60% of the patients. Brain lesions were found distributed at 46 different brain sites. Patients with different lesion localization had different success in solving riddles. Patients with perisylvian cortex brain lesions, or patients with Wernicke and global aphasia, had the poorest results. The group with SLDs had an average success of solved riddles of 26.76% (p = 0.000. The group with right-sided functional impairments had average success of 37.14%, and the group with functional impairments of the left side of the body 56.88% (p = 0.002. Conclusion. Most patients with SLDs had a low ability of solving riddles. Most of the patients with left brain lesions and perisylvian cortex damage demonstrated lower ability in solving riddles in relation to patients with right hemisphere lesions.

  10. Riddles in mathematics a book of paradoxes

    CERN Document Server

    Northrop, Eugene P

    1944-01-01

    Two fathers and two sons leave town. This reduces the population of the town by three. True? Yes, if the trio consists of a father, son, and grandson. This entertaining collection consists of more than 200 such riddles, drawn from every branch of mathematics. Math enthusiasts of all ages will enjoy sharpening their wits with riddles rooted in areas from arithmetic to calculus, covering a wide range of subjects that includes geometry, trigonometry, algebra, concepts of the infinite, probability, and logic. But only an elementary knowledge of mathematics is needed to find amusement in this imagi

  11. The Riddle of a Riddle

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    Ivan Gaskell

    2008-01-01

    Full Text Available This paper examines the distinction made by Arthur C. Danto between artworks and what he terms "mere real things." It presents an eighteenth-century tool for sifting grain (a riddle as a case study in the contexts of first, the house of its first known owner, General Artemas Ward (1727-1800; second, an exhibitioin 2006-7 drawn from the contents of that house pointedly held in an art museum; and, third, the likely maker of the object, a member of Hassanimisco Band of Nipmuc Indians. It examines the equivocal position of objects such as this in Danto's estimation, things that he considers to be "under contest," and asks whether the distinction between artworks and mere real things has any pertinence when artifacts can be used or regarded so variously in the course of their existence, whether as tools, symbols, artworks, or living beings.

  12. The riddle of Siegfried: exploring methods and psychological perspectives in analytical psychology.

    Science.gov (United States)

    Barreto, Marco Heleno

    2016-02-01

    Jung's dream of the killing of Siegfried poses a riddle: why did the unconscious choose precisely Siegfried as the hero to be murdered? Jung himself declares that he does not know. This paper attempts to decipher this riddle using three distinct methodological approaches accepted by Jung, two of them in fact grounded in his theories of dream interpretation. Besides presenting some possible answers to the riddle of Siegfried, this interpretative reflection brings to light the discrepancy of the psychological perspectives created by the heterogeneity of methods within analytical psychology. © 2016, The Society of Analytical Psychology.

  13. Lacanian Reading of Marsha Norman's Night, Mother

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    Khadijeh Taherifard

    2017-05-01

    Full Text Available This paper offers a Lacanian/feminist reading of Night, Mother by the American playwright Marsha Norman. The play Night, Mother will be read according to Lacan’s point of view and the concepts of identity and identity formation are studied in this paper. The play will be analyzed based on the Lacanian concepts of the contrast between the Imaginary Order and the Symbolic Order, and the notion of Death Drive, suggesting that in the play Jessie represents the Symbolic Order and her mother, Thelma, represents the Imaginary Order. The notion of Death Drive and its omnipresence in Jessie’s psyche is discussed and emphasized. Thelma functions as the Other for Jessie, while her father functions as the Mother, a reversal of gender roles in the Lacanian reading. Moreover, the relationship between some of the concepts are explained. It will be explicated how the play can be brought in line with a feminist reading of Lacan by reversing the stereotypical gender roles and subsequently getting close to post-feminist authors.

  14. American Offensive Funny Riddles: A Critical Metaphor Analysis

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    Ahmed Sahib Jabir Mubarak

    2018-01-01

    Full Text Available The paradox in the offensive humor lies in the assumption that what evokes laughter can be harmful for someone. Linguistically, the offense can be expressed directly and indirectly, additionally, humor, including riddles is one of the most effective ways to show offense or aggression toward someone. Humor, on the other hand, is mostly expressed indirectly. Metaphoric forms are said to be one of the most appealing strategies of humor language. The present study aims at applying a critical metaphor analysis of some randomly selected American offensive humorous riddles related to various aspects of offense like race and nation. In this approach to critical discourse analysis, the cognitive aspect is added for the sake of analyzing figurative forms like metaphor which is considered as an important part of ideology. Thus, critical metaphor analysis covers both social and cognitive aspects. It is concluded that offensive jokes (namely funny riddles can be used as a tool to measure the aggressiveness towards certain social aspects like race; on the other hand, metaphors afford indications of facets of power, inequality and people ideologies in American society.

  15. Albert Einstein and the Quantum Riddle

    Science.gov (United States)

    Lande, Alfred

    1974-01-01

    Derives a systematic structure contributing to the solution of the quantum riddle in Einstein's sense by deducing quantum mechanics from the postulates of symmetry, correspondence, and covariance. Indicates that the systematic presentation is in agreement with quantum mechanics established by Schroedinger, Born, and Heisenberg. (CC)

  16. The Riddle of the Apparently Hollow Himalaya

    Indian Academy of Sciences (India)

    The Riddle of the Apparently Hollow Himalaya. Ramesh .... It was as if the Himalayas were hollow inside. ... block would be consistent with the ground elevation in such a ... Alternative models and possible preference: Many refinements of.

  17. On-Off Intermittency and Riddled Basins of Attraction in a Coupled Map System

    DEFF Research Database (Denmark)

    Laugesen, J.; Mosekilde, Erik; Maistrenko, Yu.L.

    1998-01-01

    state are obtained. Different types of riddling bifurcation are described, and we show how the existence of an absorbing area inside the basin of attraction can account for the distinction between local and global riddling as well as for the distinction between hysteric and non-hysteric blowout....

  18. Global properties of symmetric competition models with riddling and blowout phenomena

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    Giant-italo Bischi

    2000-01-01

    Full Text Available In this paper the problem of chaos synchronization, and the related phenomena of riddling, blowout and on–off intermittency, are considered for discrete time competition models with identical competitors. The global properties which determine the different effects of riddling and blowout bifurcations are studied by the method of critical curves, a tool for the study of the global dynamical properties of two-dimensional noninvertible maps. These techniques are applied to the study of a dynamic market-share competition model.

  19. Transverse instability and riddled basins in a system of two coupled logistic maps

    DEFF Research Database (Denmark)

    Maistrenko, Yu.L.; Maistrenko, V.L.; Popovich, A.

    1998-01-01

    The paper examines the conditions for the appearance of riddled basins of attraction for a system of two symmetrically coupled logistic maps. We determine the regions in parameter space where the transverse Lyapunov exponent is negative and obtain the bifurcation curves for the transverse...... destabilization of low-periodic orbits embedded in the synchronized chaotic state. The changes in the attractor and its basin of attraction when scanning accross the riddling and blowout bifurcations are explained....

  20. Lacanian Psychoanalytical Theories in Marsha Norman’s ‘Night, Mother

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    Alieyh Alsadat Jafari

    2015-05-01

    Full Text Available Marsha Norman’s ‘Night, Mother (1983, is a great American play with psychological basis and it is considered as a feminist play. The present paper investigates it in the light of Jacques Lacan’s psychoanalytical theories which serve as a methodology in psychoanalytic criticism. Lacan knows the human psyche formed by the three interacting ‘orders’ of the Imaginary, Symbolic, and Real. He argues that the roles of ‘father’, ‘mother’, ‘Object petit a’, ‘Jouissance’, ‘the Name-of-the-Father’, ‘Big Other’ and ‘others’ are also significant in affecting one’s psyche. The characters of ‘Night, Mother are Lacanian ‘subjects’ whose lives have been embodiments of Lacan’s psychoanalytical theories, especially Jessie whose disorders, behaviors, reactions to the ‘others’, frustration, committing suicide, and death indicate that many familial, social and mental issues have affected her psyche, and they are crystalized by psychoanalytical theories of Lacan in this paper.

  1. Einstein's Riddle as a Tool for Profiling Students

    Science.gov (United States)

    Özeke, Vildan; Akçapina, Gökhan

    2016-01-01

    There are many computer games, learning environments, online tutoring systems or computerized tools which keeps the track of the user while learning or engaging in the activities. This paper presents results from an exploratory study and aims to group students regarding their behavior data while solving the Einstein's riddle. 45 undergraduate…

  2. Back from the Nikitsky Gates Theater: Reflections on Cross-Cultural Concerns in the Staging of Marsha Norman's "'night, Mother" in Moscow.

    Science.gov (United States)

    Karter, M. Joshua

    1994-01-01

    Discusses some of the problems the author encountered in staging a production of Marsha Norman's "'night, Mother" in Moscow. States that the area of largest concern was cultural variables, and whether a Russian audience would be able to understand some of the references. Concludes that, despite cultural differences, the audience was…

  3. Wishes and Riddles: Symbolic Imagery in Chinese Art.

    Science.gov (United States)

    Asian Art Museum of San Francisco, CA.

    This teacher's packet accompanies a slide presentation on the wishes and riddles found in myths and rebuses in Chinese art. The packet contains: (1) an introductory essay describing symbolism used in the art of various dynasties of China; (2) a slide list describing the art depicted on each slide with time period and dimensions of the piece; (3) a…

  4. Riddled Basins of Attraction for Synchronized Type-I Intermittency

    DEFF Research Database (Denmark)

    Mancher, Martin; Nordahn, Morten; Mosekilde, Erik

    1998-01-01

    Chaotic mortion resticted to an invariant subspace of total phase space may be associated with basins of attraction that are riddled with holes belonging to the basin of another limiting state. We study the emergence of such basins of two coupled one-dimensional maps, each exhibiting type...

  5. Adivinanzas audiovisuales para ejercitar el pensamiento creativo infantil Audiovisual Riddles to Stimulate Children’s Creative Thinking

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    Jorge Montalvo Castro

    2011-03-01

    Full Text Available Para resolver una adivinanza hay que asociar ideas, analizar metáforas, descubrir analogías. Por eso, impulsar esta forma de entretenimiento infantil es un modo de ejercitar el pensamiento creativo. Sin embargo, existe un problema: las adivinanzas tradicionales son formas literarias que corresponden a una época pre-digital. ¿Cómo lograr, entonces, que tengan mayor aceptación entre los nativos digitales? Una posible solución sería crear adivinanzas audiovisuales diseñadas especialmente para YouTube. En esta investigación se realizaron cinco prototipos de adivinanzas audiovisuales con características creativas diferentes y se validaron con estudiantes de tercero a sexto grado de educación primaria. Los resultados de la validación permitieron identificar las actitudes, reacciones, interpretaciones y modos de razonamiento de los niños y niñas cuando intentan resolver este tipo de adivinanzas. También se identificaron los recursos de lenguaje y formatos creativos que funcionan mejor en una adivinanza audiovisual. En las conclusiones se destaca la necesidad de formular correctamente los enunciados de las adivinanzas audiovisuales y sus respectivas «pistas» para que los niños y niñas tengan la satisfacción intelectual y emocional de resolverlas. Se precisa, además, que leer o escuchar una adivinanza tradicional representa una experiencia cognitiva y sensorial muy distinta que interactuar con esa misma adivinanza en un lenguaje multimedia. Finalmente, se discute y analiza el rol mediador del docente y la importancia del aprendizaje colaborativo en los proyectos educativos que emplean tecnologías digitales.Solving riddles involves association of ideas, analysis of metaphors, and discovery of analogies. Therefore, promoting this type of children’s entertainment is a way to develop creative thinking. However, there is a problem: traditional riddles are literary forms that correspond to a pre-digital era. How can we increase its

  6. Riddle Appreciation and Reading Comprehension in Cantonese-Speaking Children

    Science.gov (United States)

    Tang, Ivy N. Y.; To, Carol K. S.; Weekes, Brendan S.

    2013-01-01

    Purpose: Inference-making skills are necessary for reading comprehension. Training in riddle appreciation is an effective way to improve reading comprehension among English-speaking children. However, it is not clear whether these methods generalize to other writing systems. The goal of the present study was to investigate the relationship between…

  7. Puzzle Pedagogy: A Use of Riddles in Mathematics Education

    Science.gov (United States)

    Farnell, Elin

    2017-01-01

    In this article, I present a collection of puzzles appropriate for use in a variety of undergraduate courses, along with suggestions for relevant discussion. Logic puzzles and riddles have long been sources of amusement for mathematicians and the general public alike. I describe the use of puzzles in a classroom setting, and argue for their use as…

  8. Driving-induced multistability in coupled chaotic oscillators: Symmetries and riddled basins

    Energy Technology Data Exchange (ETDEWEB)

    Ujjwal, Sangeeta Rani; Ramaswamy, Ram [School of Physical Sciences, Jawaharlal Nehru University, New Delhi 110067 (India); Punetha, Nirmal; Prasad, Awadhesh [Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Agrawal, Manish [Department of Physics, Sri Aurobindo College, University of Delhi, New Delhi 110017 (India)

    2016-06-15

    We study the multistability that results when a chaotic response system that has an invariant symmetry is driven by another chaotic oscillator. We observe that there is a transition from a desynchronized state to a situation of multistability. In the case considered, there are three coexisting attractors, two of which are synchronized and one is desynchronized. For large coupling, the asynchronous attractor disappears, leaving the system bistable. We study the basins of attraction of the system in the regime of multistability. The three attractor basins are interwoven in a complex manner, with extensive riddling within a sizeable region of (but not the entire) phase space. A quantitative characterization of the riddling behavior is made via the so–called uncertainty exponent, as well as by evaluating the scaling behavior of tongue–like structures emanating from the synchronization manifold.

  9. Juegos, Canciones, Poemas y Adivinanzas (Games, Songs, Poems and Riddles).

    Science.gov (United States)

    Toro, Leonor; And Others

    Printed in Spanish, this booklet contains games, songs, poems, riddles, and sayings for use with Puerto Rican migrant children. Eleven matching exercises present Spanish vocabulary related to clothing, food, and musical instruments. Eleven word search games teach Spanish names for body parts, masculine and feminine nouns, famous names, fruits and…

  10. PICTORIAL RIDDLE MELALUI PEMBELAJARAN ATTENTION, RELEVANCE, CONFIDENCE, SATISFACTION (ARCS UNTUK MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH DAN MOTIVASI BERPRESTASI SISWA

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    Siti Masfuah

    2016-08-01

    Full Text Available Penelitian ini bertujuan mengetahui penerapan metode pictorial riddle melalui pembelajaran ARCS untuk meningkatkan kemampuan pemecahan masalah dan motivasi berprestasi siswa. Metode pictorial riddle yang digunakan adalah jenis komik sains sederhana yang berisi tentang cerita petualangan yang dihubungkan dengan materi sains. Penelitian ini merupakan penelitian pra eksperimen dengan desain one shot case study karena tidak ada kelas kontrol. Subyek penelitian ini adalah siswa kelas V SD Negeri 4 Rendeng Kudus yang dipilih dengan teknik purposive sampling. Variabel bebas penelitian ini adalah metode pictorial riddle dengan jenis komik sains yang diterapkan pada model pembelajaran ARCS, sedangkan variabel terikatnya adalah kemampuan pemecahan masalah dan motivasi berprestasi siswa. Teknik analisis data yang digunakan adalah uji t satu sampel yang dibandingkan nilai KKM. Berdasarkan analisis data diketahui bahwa rata-rata kemampuan pemecahan masalah siswa sebesar 82,75, sedangkan rata-rata motivasi berprestasi siswa sebesar 80,31. Berdasarkan pengujian hipotesis, rata-rata kemampuan pemecahan masalah dan motivasi berprestasi siswa kelas V SD Negeri 4 Rendeng lebih dari atau sama dengan 75. Dengan demikian, dapat disimpulkan bahwa metode pictorial riddle melalui pembelajaran ARCS dapat meningkatkan kemampuan pemecahan masalah dan motivasi berprestasi siswa.

  11. Coexisting multiple attractors and riddled basins of a memristive system.

    Science.gov (United States)

    Wang, Guangyi; Yuan, Fang; Chen, Guanrong; Zhang, Yu

    2018-01-01

    In this paper, a new memristor-based chaotic system is designed, analyzed, and implemented. Multistability, multiple attractors, and complex riddled basins are observed from the system, which are investigated along with other dynamical behaviors such as equilibrium points and their stabilities, symmetrical bifurcation diagrams, and sustained chaotic states. With different sets of system parameters, the system can also generate various multi-scroll attractors. Finally, the system is realized by experimental circuits.

  12. Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show

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    Md. Al Mamun

    2011-11-01

    Full Text Available From the conventional Bird’s eye, cancer initiation and metastasis are generally intended to be understood beneath the light of classical clonal genetic, epigenetic and cancer stem cell model. But inspite decades of investigation, molecular biology has shown hard success to give Eagle’s eye in unraveling the riddle of cancer. And it seems, tiring Tom runs in vague behind naughty Jerry.

  13. Oscar Riddle's Science, a Special Bird, & the Founding of the NABT

    Science.gov (United States)

    Vandervoort, Frances S.

    2013-01-01

    Oscar Riddle, born in Indiana in 1877, was an ardent evolutionist and a key player in the founding of the National Association of Biology Teachers in 1938. He studied heredity and behavior in domestic pigeons and doves with Charles O. Whitman of the University of Chicago, received his Ph.D. in zoology in 1907, and in 1912 began a long career at…

  14. PENERAPAN PENDEKATAN INKUIRI TERBIMBING DENGAN METODE PICTORIAL RIDDLE UNTUK MENINGKATKAN PEMAHAMAN KONSEP FISIKA SISWA

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    Muhammad Minan Chusni

    2016-09-01

    The results showed that the application of guided inquiry learning with pictorial riddle method can improve students' understanding of the concept in the first cycle with an average value of 42.93 into 50.71 and the second cycle increased to 67.50 and in the third cycle into 80.71. Similarly, the students' motivation to learn physics class is also quite good with a yield of 63.57%.

  15. Continuity and Discontinuity, Change and Duration: Hobbes' Riddle of the Theseus and the Diversity of Historical Logics.

    Science.gov (United States)

    Blum, Mark E.

    1996-01-01

    Reiterates the need for an understanding of the concepts of continuity and change, not simply in the representation of historical events, but in the writing and study of history. Uses Thomas Hobbes's riddle of Theseus to illustrate the need for multiple readings and critical analysis in history instruction. (MJP)

  16. The riddle of sex: biological theories of sexual difference in the early twentieth-century.

    Science.gov (United States)

    Ha, Nathan Q

    2011-01-01

    At the turn of the twentieth century, biologists such as Oscar Riddle, Thomas Hunt Morgan, Frank Lillie, and Richard Goldschmidt all puzzled over the question of sexual difference, the distinction between male and female. They all offered competing explanations for the biological cause of this difference, and engaged in a fierce debate over the primacy of their respective theories. Riddle propounded a metabolic theory of sex dating from the late-nineteenth century suggesting that metabolism lay at the heart of sexual difference. Thomas Hunt Morgan insisted on the priority of chromosomes, Frank Lillie emphasized the importance of hormones, while Richard Goldschmidt supported a mixed model involving both chromosomes and hormones. In this paper, I will illustrate how the older metabolic theory of sex was displaced when those who argued for the relatively newer theories of chromosomes and hormones gradually formed an alliance that accommodated each other and excluded the metabolic theory of sex. By doing so, proponents of chromosomes and hormones established their authority over the question of sexual difference as they laid the foundations for the new disciplines of genetics and endocrinology. Their debate raised urgent questions about what constituted sexual difference, and how scientists envisioned the plasticity and controllability of this difference. These theories also had immediate political and cultural consequences at the turn of the twentieth century, especially for the eugenic and feminist movements, both of which were heavily invested in knowledge of sex and its determination, ascertainment, and command.

  17. Greater Emphasis on Female Attractiveness in Homo Sapiens: A Revised Solution to an Old Evolutionary Riddle

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    Jonathan Gottschall

    2007-04-01

    Full Text Available Substantial evidence from psychology and cross-cultural anthropology supports a general rule of greater emphasis on female physical attractiveness in Homo sapiens. As sensed by Darwin (1871 and clarified by Trivers (1972, generally higher female parental investment is a key determinant of a common pattern of sexual selection in which male animals are more competitive, more eager sexually and more conspicuous in courtship display, ornamentation, and coloration. Therefore, given the larger minimal and average parental investment of human females, keener physical attractiveness pressure among women has long been considered an evolutionary riddle. This paper briefly surveys previous thinking on the question, before offering a revised explanation for why we should expect humans to sharply depart from general zoological pattern of greater emphasis on male attractiveness. This contribution hinges on the argument that humans have been seen as anomalies mainly because we have been held up to the wrong zoological comparison groups. I argue that humans are a partially sex-role reversed species, and more emphasis on female physical attractiveness is relatively common in such species. This solution to the riddle, like those of other evolutionists, is based on peculiarities in human mating behavior, so this paper is also presented as a refinement of current thinking about the evolution of human mating preferences.

  18. Bilmecelerin Dil-Düşünme Bağlamında Eğitimdeki Yeri ve Önemi The Place and Importance of Riddles in the Context of Language and Thinking

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    Elif Emine BALTA

    2013-03-01

    Full Text Available Riddles, the entertaining works of folk literature with simple appearances (structures, deep backgrounds and artistic expressions, also have the moral value of carrying the centuries of accumulated cultural traces into today. In daily life, riddle has lost its old popularity.This is quite normal. Because changes in life conditions, variations inthe quality of social environments, individualization and similar reasonshave altered the interests and pleasures of people as well as their needsand understandings.In academic context, studies on riddles have been limited with thefield of folklore. The valuable studies done on this field have not beensufficiently evaluated within the scope of education and teaching.Today, it is seen that, riddles do not take place within framework ofeducation and teaching. However, riddles have richness and deepnessthat can be used as a means of reaching success in not merely teachinglanguage and concepts but also in closely related thought. The biggestcontribution of riddles to the education and teaching process is seen innative language education. Riddles can be seen as a means of teachingconcepts and enriching word treasure. In a riddle, the process ofsearching answer is dynamic; that is, one compares all the conceptspassing through his mind with the features given in the question.“Clearly, riddles correlate with high order thinking like creativethinking, critical thinking and problem solving. So riddles must beappreciated educational and intellectual context and included ineducation and teaching environments”. In this study, the place andsignificance of riddle as an effective tool and a rich stimulant ineducation and teaching will be determined and explained. Bilmeceler, sade görünümleri, derin arka planları ve sanatlı söyleyişleri ile eğlenceli halk edebiyatı ürünleri olup yüzyıllar boyu, biriktirmiş olduğu kültürel ögeleri günümüze taşıma gibi manevi değere sahiptir. Gündelik hayatta

  19. [Riddles in human tuberculous infection].

    Science.gov (United States)

    Tsuyuguchi, I

    2000-10-01

    Tuberculosis is indeed an infectious disease caused by Mycobacterium tuberculosis. However, only a small percentage of individuals infected develops overt disease, tuberculosis whereas the infected bacilli persist alive years long within the vast majority of persons infected but remained healthy. There are several riddles or enigmas in the natural history of M. tuberculosis infection in humans. Some of them are as follows: 1. What is the virulence of M. tuberculosis? 2. How does M. tuberculosis persist dormant within the host? 3. What determines the development of disease from remaining healthy after infection with M. tuberculosis? 4. What is the mechanism of "endogenous reactivation" of dormant M. tuberculosis within the host? 5. Can we expect more potent anti-TB vaccine than BCG in near future? Most of these issues cited above remain unsolved. What is urgently needed today to answer correctly to these questions is the production of appropriate animal model of tuberculosis infection which mimics human tuberculosis. Murine TB does not reflect human TB at all. What characterizes the mycobacterial organism is its armour-plated unique cell wall structure which is rich in lipid and carbohydrate. Cord factor or trehalose dimycolate (TDM), the main component of cell wall, has once been regarded as the virulence factor of mycobacteria. Cord factor is responsible for the pathogenesis of TB and cachexia or even death of the patients infected. However, cord factor in itself is not toxic but exerts its detrimental effect to the host through the excessive stimulation of the host's immune system to produce abundant varied cytokines including TNF-alpha. How to evade this embarrassing effect of mycobacterial cell wall component on the host immune system seems very important for the future development of better TB vaccine than the currently used BCG.

  20. comparative beef production from buli,s, steers and heifers under

    African Journals Online (AJOL)

    steers, although statistically significant, were much srnaller than differences obtained in the present study. Out of a maximum possible grading of 20 points, bulls obtained an average of 12,3 points (Grade I -) which is considerably lower than the grading points obtained by steers (16,3 = Prime) or by heifers (17,5 = Prime+).

  1. The last Fermat theorem. The story of the riddle that has defied the greatest minds in the world during 358 years

    International Nuclear Information System (INIS)

    Singh, S.

    1998-01-01

    Pierre de Fermat, one of the greatest French mathematician of the seventeenth century, noticed in the margin of his exercise book 'X n + Y n Z n impossible if n upper than 2, i have found a wonderful solution but i am short of place to develop it here'. Only in 1993 a young British man, Andrew Wiles, professor at Princeton, after seven years of work settled this riddle. That is that story that is told here. (N.C.)

  2. A riddled basin escaping crisis and the universality in an integrate-and-fire circuit

    Science.gov (United States)

    Dai, Jun; He, Da-Ren; Xu, Xiu-Lian; Hu, Chin-Kun

    2018-06-01

    We investigate an integrate-and-fire model of an electronic relaxation oscillator, which can be described by the discontinuous and non-invertible composition of two mapping functions f1 and f2, with f1 being dissipative. Depending on a control parameter d, f2 can be conservative (for d =dc = 1) or dissipative (for d >dc). We find a kind of crisis, which is induced by the escape from a riddled-like attraction basin sea in the phase space. The averaged crisis transient lifetime (〈 τ 〉), the relative measure of the fat fractal forbidden network (η), and the measure of the escaping hole (Δ) show clear scaling behaviors: 〈 τ 〉 ∝(d -dc) - γ, η ∝(d -dc) σ, and Δ ∝(d -dc) α. Extending an argument by Jiang et al. (2004), we derive γ = σ + α, which agrees well with numerical simulation data.

  3. Convenient procedures for the α-metallation of vinylic ethers and thioethers

    NARCIS (Netherlands)

    Verkruijsse, H.D.; Brandsma, L.; Schleyer, P. von R.

    1987-01-01

    Ethyl vinyl ether H2C=CHOC2H5 and the analogous cyclic vinylic ethers dehydrofuran and 2,3-dihydropyran can be potassiated at −20°C in the α-position with a 1/1/1 molar mixture of BuLi, t-BuOK and TMEDA in hexane. Methyl vinyl sulfide is potassiated very smoothly by a 1/1 molar mixture of BuLi and

  4. RIDDLE: Race and ethnicity Imputation from Disease history with Deep LEarning.

    Directory of Open Access Journals (Sweden)

    Ji-Sung Kim

    2018-04-01

    Full Text Available Anonymized electronic medical records are an increasingly popular source of research data. However, these datasets often lack race and ethnicity information. This creates problems for researchers modeling human disease, as race and ethnicity are powerful confounders for many health exposures and treatment outcomes; race and ethnicity are closely linked to population-specific genetic variation. We showed that deep neural networks generate more accurate estimates for missing racial and ethnic information than competing methods (e.g., logistic regression, random forest, support vector machines, and gradient-boosted decision trees. RIDDLE yielded significantly better classification performance across all metrics that were considered: accuracy, cross-entropy loss (error, precision, recall, and area under the curve for receiver operating characteristic plots (all p < 10-9. We made specific efforts to interpret the trained neural network models to identify, quantify, and visualize medical features which are predictive of race and ethnicity. We used these characterizations of informative features to perform a systematic comparison of differential disease patterns by race and ethnicity. The fact that clinical histories are informative for imputing race and ethnicity could reflect (1 a skewed distribution of blue- and white-collar professions across racial and ethnic groups, (2 uneven accessibility and subjective importance of prophylactic health, (3 possible variation in lifestyle, such as dietary habits, and (4 differences in background genetic variation which predispose to diseases.

  5. RIDDLE: Race and ethnicity Imputation from Disease history with Deep LEarning

    KAUST Repository

    Kim, Ji-Sung

    2018-04-26

    Anonymized electronic medical records are an increasingly popular source of research data. However, these datasets often lack race and ethnicity information. This creates problems for researchers modeling human disease, as race and ethnicity are powerful confounders for many health exposures and treatment outcomes; race and ethnicity are closely linked to population-specific genetic variation. We showed that deep neural networks generate more accurate estimates for missing racial and ethnic information than competing methods (e.g., logistic regression, random forest, support vector machines, and gradient-boosted decision trees). RIDDLE yielded significantly better classification performance across all metrics that were considered: accuracy, cross-entropy loss (error), precision, recall, and area under the curve for receiver operating characteristic plots (all p < 10-9). We made specific efforts to interpret the trained neural network models to identify, quantify, and visualize medical features which are predictive of race and ethnicity. We used these characterizations of informative features to perform a systematic comparison of differential disease patterns by race and ethnicity. The fact that clinical histories are informative for imputing race and ethnicity could reflect (1) a skewed distribution of blue- and white-collar professions across racial and ethnic groups, (2) uneven accessibility and subjective importance of prophylactic health, (3) possible variation in lifestyle, such as dietary habits, and (4) differences in background genetic variation which predispose to diseases.

  6. Preparation of amidoxime-fiber adsorbents based on poly(methacrylonitrile) for recovery of uranium from seawater

    International Nuclear Information System (INIS)

    Kabay, N.

    1994-01-01

    Polymerization of methacrylonitrile was performed with anionic initiators as reported in the literature. The molecular weight of the polymer produced using BuLi as initiator at 0 ± 2 degrees C was on the order of 10 5 . Maximum conversion was 97% with BuLi initiator. For comparison, methacrylonitrile was polymerized with diethylmagnesium in dioxane at 70 degrees C. High-molecular weight polymers with 50-60% conversions were produced by diethylmagnesium initiator. The polymethacrylonitrile obtained by BuLi initiator was used for the fiber production process. The conversion of nitrile was performed by treatment with 3% NH 2 OH in MeOH at 80 degrees C. The amidoxime-fiber adsorbent gave a large adsorption rate, such as 176 μg of U/g of adsorbent/day, in a batchwise seawater adsorption test. 36 refs., 1 fig., 3 tabs

  7. Embry-Riddle Aeronautical University multispectral sensor and data fusion laboratory: a model for distributed research and education

    Science.gov (United States)

    McMullen, Sonya A. H.; Henderson, Troy; Ison, David

    2017-05-01

    The miniaturization of unmanned systems and spacecraft, as well as computing and sensor technologies, has opened new opportunities in the areas of remote sensing and multi-sensor data fusion for a variety of applications. Remote sensing and data fusion historically have been the purview of large government organizations, such as the Department of Defense (DoD), National Aeronautics and Space Administration (NASA), and National Geospatial-Intelligence Agency (NGA) due to the high cost and complexity of developing, fielding, and operating such systems. However, miniaturized computers with high capacity processing capabilities, small and affordable sensors, and emerging, commercially available platforms such as UAS and CubeSats to carry such sensors, have allowed for a vast range of novel applications. In order to leverage these developments, Embry-Riddle Aeronautical University (ERAU) has developed an advanced sensor and data fusion laboratory to research component capabilities and their employment on a wide-range of autonomous, robotic, and transportation systems. This lab is unique in several ways, for example, it provides a traditional campus laboratory for students and faculty to model and test sensors in a range of scenarios, process multi-sensor data sets (both simulated and experimental), and analyze results. Moreover, such allows for "virtual" modeling, testing, and teaching capability reaching beyond the physical confines of the facility for use among ERAU Worldwide students and faculty located around the globe. Although other institutions such as Georgia Institute of Technology, Lockheed Martin, University of Dayton, and University of Central Florida have optical sensor laboratories, the ERAU virtual concept is the first such lab to expand to multispectral sensors and data fusion, while focusing on the data collection and data products and not on the manufacturing aspect. Further, the initiative is a unique effort among Embry-Riddle faculty to develop multi

  8. Dynamic neural network of insight: a functional magnetic resonance imaging study on solving Chinese 'chengyu' riddles.

    Directory of Open Access Journals (Sweden)

    Qingbai Zhao

    Full Text Available The key components of insight include breaking mental sets and forming the novel, task-related associations. The majority of researchers have agreed that the anterior cingulate cortex may mediate processes of breaking one's mental set, while the exact neural correlates of forming novel associations are still debatable. In the present study, we used a paradigm of answer selection to explore brain activations of insight by using event-related functional magnetic resonance imaging during solving Chinese 'chengyu' (in Chinese pinyin riddles. Based on the participant's choice, the trials were classified into the insight and non-insight conditions. Both stimulus-locked and response-locked analyses are conducted to detect the neural activity corresponding to the early and late periods of insight solution, respectively. Our data indicate that the early period of insight solution shows more activation in the middle temporal gyrus, the middle frontal gyrus and the anterior cingulate cortex. These activities might be associated to the extensive semantic processing, as well as detecting and resolving cognitive conflicts. In contrast, the late period of insight solution produced increased activities in the hippocampus and the amygdala, possibly reflecting the forming of novel association and the concomitant "Aha" feeling. Our study supports the key role of hippocampus in forming novel associations, and indicates a dynamic neural network during insight solution.

  9. Reikšmės keitimo kryptis mįslėse

    OpenAIRE

    Kensminienė, Aelita

    2003-01-01

    The author follows an assumption that riddle texts present metaphorical "explanations" of real objects (answers). The table, compiled by using the list of the most popular riddle types, demonstrates the tendency of meaning transformation, accomplished by riddles. This enables the author to conclude that materiality is relatively unrepresentative in the riddle texts, being more typical of the answers, however. The majority in riddle texts attempt explaining a simpler object by use of a more co...

  10. The Riddle of a Human Being: A Human Singularity of Co-evolutionary Processes

    Directory of Open Access Journals (Sweden)

    Helena N. Knyazeva

    2008-10-01

    Full Text Available span style="font-size: 10pt; font-family: #39;Times New Roman#39;"The theory of self-organization of complex systems studies laws of sustainable co-evolutionary development of structures having different speeds of development as well as laws of assembling of a complex evolutionary whole from parts when some elements of ldquo;memoryrdquo; (the biological memory, i.e. DNA, the memory of culture, i.e. the cultural and historical traditions, etc. must be included. The theory reveals general rules of nonlinear synthesis of complex evolutionary structures. The most important and paradoxical consequences of the holistic view, including an approach to solving the riddle of human personality, are as follows: 1 the explanation why and under what conditions a part (a human can be more complex than a whole (society; 2 in order to reconstruct society it is necessary to change an individual but not by cutting off the supposed undesirable past, since a human being as a microcosm is the synthesis of all previous stages of evolution, and as a result of repression of, it would seem, the wild past one can extinguish a ldquo;divine sparkrdquo; in his soul; 3 in the physical sense, singularity denotes a moment of instability, phase transition; one can talk about the human singularity of co-evolutionary processes, since in such a moment of instability individual actions of a human can play a key role in determining a channel of further development as well as in appearance of a new pattern of collective behavior in society; 4 as the models of nonlinear dynamics, elaborated at the Keldysh Institute of Applied Mathematics of the Russian Academy of Sciences in Moscow, show, there is a possibility of a direct influence of the future and even a touch of an infinitely remote future in certain evolutionary regimes and under rigorously definite conditions, more over, it turns out that such a possibility exists only for a human (admittedly, through a specific state of being

  11. Pärdi muusikamaja projektid näitusel

    Index Scriptorium Estoniae

    2009-01-01

    Rakvere Pauluse kiriku rekonstrueerimise võistlustööde näitus Eesti Arhitektuurimuuseumis. Konkursi eesmärk oli välja selgitada parim lahendus spordisaalina tegutseva kiriku muutmiseks Arvo Pärdi muusikamajaks. Võidutööks oli Kristiina Aasvee, Kristiina Hussari ja Anne Kose projekt "tintin'na:buli"

  12. Synthesis of marasin and 9-Me-marasin (nona- and deca-6,8-diyne-2,4-dienol)

    NARCIS (Netherlands)

    Koten, G. van; Graaf, W. de; Smits, A.; Boersma, J.; Hoekstra, W.P.M.

    1988-01-01

    3, 4-Pentadienol was protected with ethyl vinyl ether and regioselectively (70%) deprotonated at the terminal position by treatment with BuLi in THF at low temperature. Starting from the so obtained lithium compound, Marasin (nona-6,8-diyne-3,4-dienol) (1a) and 9-Me-Marasin

  13. New route for the metallation of trihydroheptaphosphine P7H3 with butyllithium

    International Nuclear Information System (INIS)

    Milyukov, V.A.; Kataev, A.V.; Sinyashin, O.G.; Khej-Khokkins, E.

    2006-01-01

    A new route for the metallation of heptaphosphine P 7 H 3 with BuLi, namely, decomposition of the nortricyclane P 7 unit to form dilithium hexadecaphosphide Li 2 P 16 , was found. The composition and structure of the resulting compound were verified by mass spectrometry and 31 P NMR [ru

  14. Wittgenstein i zagadka Anzelma

    Directory of Open Access Journals (Sweden)

    Jakub Gomułka

    2013-09-01

    Full Text Available The paper is devoted to the problem of the two paradoxes: the paradox of absolute value in Wittgenstein’s Lecture on Ethics and the paradox of Anselm’s Name of God from the Proslogion. I try to present linguistic determinants of both paradoxes and point out to certain similarities between them. However, the main part of the article focuses on the solution of Anselm’s paradox given by Cora Diamond, the prominent Wittgensteinian scholar in her 1995 book The Realistic Spirit. Diamond develops extensive comparison of the concept of that than which nothing greater can be conceived and a series of peculiar riddles – she calls the Anselm’s concept the great riddle, since, as in other riddles presented, we cannot deal with it in a usual way. The author of The Realistic Spirit shows that what enables us to resolve, say, the riddle of Sphinx, is our obtaining a new way of understanding of the words which compose the riddle itself, because the standard understanding will not lead us to any answer. However, when it comes to the great riddle we know that we cannot obtain any way of understanding which will enable us to conceive it. This does not mean that the riddle cannot make any sense for us. We can believe that there is a solution (in fact, we know the solution which has been given to us in the Revelation, but we cannot understand it and hence we can treat the great riddle as an euqation which we lack proof but we know there is one. As Diamond calls it, we have the promissory meaning of the riddle. In my opinion the idea of the promissory meaning as an interesting solution of Anselm’s paradox, but I notice that the idea itself is conditioned by religious faith or by something I call the empathic atheism (in short: an attitude which let atheists to imagine the believers’ point of view.

  15. Diagnostic riddles

    Science.gov (United States)

    Sileo, L.; Greiner, E.C.

    1993-01-01

    A bridled white-eye (Zosterops conspicillata) was captured in a mist net on the island of Saipan and transported to the island of Guam for an experimental study. Beginning on day three, it was immunosuppressed by intramuscular injections of dexamethasone. It was unexpectedly found dead on day 20, at which time it had lost 0.9 g (12.9% of initial body weight). Gross Pathology: Despite the weight loss, the white-eye was in good flesh, with abundant subcutaneous and visceral fat. The spleen was 3 x 11 mm, about 5 times normal size. The striatum of the forebrain was congested. There were no other lesions. Histopathology: There were microscopic abnormalities in skeletal muscle, brain, and gizzard (Figs. 1 and 2; Figure 2 is from a different white-eye which had virtually identical gizzard lesions).

  16. Is Johannes 1:1 ’n ‘raaisel’? Grammatikale getuienis

    Directory of Open Access Journals (Sweden)

    Jan van der Watt

    2016-04-01

    Full Text Available Is Johannes 1:1 a ‘riddle’? Grammatical evidence. John 1:1 is one of the most famous opening lines in the Bible. No wonder that it received its proportionate attention in scholarship which is characterised by the differences of opinion regarding several issues addressed in these verses. It is suggested that these difficulties in interpreting this verse might be an implication that it is a riddle or at least has riddle-like qualities. The question to be dealt with further is whether the grammar, which is also subject of intense discussion, supports the idea that this verse might be a riddle. Keywords: John 1:1, Riddles in John, ‘God’ or ‘god’ in John, Johannine grammar

  17. Kolm ühes : uhke kirik, võimla ja kontserdisaal / Eda Post

    Index Scriptorium Estoniae

    Post, Eda, 1983-

    2009-01-01

    Rakvere Pauluse kiriku (arhitekt Alar Kotli, 1930-ndate 2. pool) Arvo Pärdi nimeliseks muusikamajaks rekonstrueerimise ja Vabaduse väljaku planeerimise rahvusvahelisest arhitektuurivõistlusest, võidutööst "Tintin'na.buli", mille autorid on Kristiina Aasvee, Kristiina Hussar ja Anne Kose OÜ-st Celander Projekt. 2. koha sai töö "Hortus Musicus", mille autorid on Emil Urbel ja Aleksandr Zverev arhitektuuribüroost Emil Urbel OÜ

  18. But All of Us Are Straight: "Marsha" Undone

    Science.gov (United States)

    Gould, Elizabeth

    2010-01-01

    The radical outside claimed by Gloria T. Hull, Patricia Bell Scott, and Barbara Smith nearly 30 years ago was comprised of black feminism and feminist race theory in the context of black lesbian studies, which had no academic precedent. What today makes their actions, words, and meaning-making brave is material realization of their subjectivities.…

  19. Riddle of radon

    International Nuclear Information System (INIS)

    O'Riordan, M.

    1996-01-01

    Why is the most significant source of human exposure to ionising radiation - and one that is so easy to reduce - not accorded the attention it deserves from those engaged in radiological protection nor the action it requires from those affected by it at work or at home? There are, after all, clear indications that high levels of radon exist and firm strands of evidence that radon causes cancer. Some national and international authorities have even developed regulations and recommendations to limit exposures. But radon still lies in the penumbra of protection because proponents of intervention lack conviction and opponents are full of passionate intensity. Little wonder that citizens are confused! (Author)

  20. Alkylation of pyridines at their 4-positions with styrenes plus yttrium reagent or benzyl Grignard reagents.

    Science.gov (United States)

    Mizumori, Tomoya; Hata, Takeshi; Urabe, Hirokazu

    2015-01-02

    A new regioselective alkylation of pyridines at their 4-position was achieved with styrenes in the presence of yttrium trichloride, BuLi, and diisobutylaluminium hydride (DIBAL-H) in THF. Alternatively, similar products were more simply prepared from pyridines and benzyl Grignard reagents. These reactions are not only a useful preparation of 4-substituted pyridines but are also complementary to other relevant reactions usually giving 2-substituted pyridines. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. The Relationship between Video Game Use and a Performance-Based Measure of Persistence

    Science.gov (United States)

    Ventura, Matthew; Shute, Valerie; Zhao, Weinan

    2013-01-01

    An online performance-based measure of persistence was developed using anagrams and riddles. Persistence was measured by recording the time spent on unsolved anagrams and riddles. Time spent on unsolved problems was correlated to a self-report measure of persistence. Additionally, frequent video game players spent longer times on unsolved problems…

  2. Volunteering in the Elementary Outreach Program Could Make You Happier | Poster

    Science.gov (United States)

    By Marsha Nelson-Duncan, Guest Writer, and Nancy Parrish, Staff Writer Did you know that volunteers in the Elementary Outreach Program (EOP) just might be happier than their coworkers who don’t volunteer?

  3. A Necessária Fricção (ou talvez não

    Directory of Open Access Journals (Sweden)

    Fontes, Bruno

    2016-07-01

    Full Text Available Review of Marsha Kinder e Tara McPherson (Eds., Transmedia Frictions: The Digital, the Arts, and the Humanities. Oakland, CA: University of California Press, 2014, 416 pp. ISBN 978-0-520-28185-1.

  4. Facile And Reversible Co Insertion Into The Ir-ch3 Bond Of [ir4(ch3)(co)8(μ4- η3-ph2pccph)(μ-pph2)

    OpenAIRE

    Vargas M.D.; Pereira R.M.S.; Braga D.; Grepioni F.

    1993-01-01

    Reaction of [Ir4H(CO)10(mu-PPh2)) with BuLi, Ph2PC=CPh and then Mel gives [Ir4(CH3)(CO)8(mu4-eta3-Ph2PCCPh)(mu-PPh2)], which undergoes a reversible two-step CO insertion under extremely mild conditions to yield Ir4{(CH3C(O)}(CO)8-(mu4:eta3-Ph2PCCPh)(mu-PPh2)] as the final product; the structures of both species have been established by X-ray diffraction studies.

  5. 78 FR 64260 - Overseas Security Advisory Council (OSAC) Meeting Notice

    Science.gov (United States)

    2013-10-28

    ... corporate security policies and procedures and will involve extensive discussion of trade secrets and proprietary commercial information that is privileged and confidential, and will discuss law enforcement... protection of U.S. business information overseas. For more information, contact Marsha Thurman, Overseas...

  6. First international conference on nonlinear problems in aviation and aerospace

    International Nuclear Information System (INIS)

    Sivasundaram, S.

    1994-01-01

    The International Conference on Nonlinear Problems in Aviation and Aerospace was held at Embry-Riddle Aeronautical University, Daytona Beach, Florida on May 9-11, 1996. This conference was sponsored by the International Federation of Nonlinear Analysts, International Federation of Information Processing, and Embry-Riddle Aeronautical University. Over one hundred engineers, scientists, and mathematicians from seventeen countries attended. These proceedings include keynote addresses, invited lectures, and contributed papers presented during the conference

  7. Cosmic ray riddle solved?

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    Full text: Physicists from Japan and the United States have discovered a possible answer to the puzzle of the origin of high energy cosmic rays that bombard Earth from all directions in space. Using data from the Japanese/US X-ray astronomical satellite ASCA, physicists have found strong evidence for the production of cosmic particles in the shock wave of a supernova remnant, the expanding fireball produced by the explosion of a star. Primary cosmic rays, mostly electrons and protons, travel near the speed of light. Each second, approximately 4 such particles cross one square centimetre of space just outside the Earth's atmosphere. Subsequently, collisions of these primary particles with atoms in the upper atmosphere produce slower secondary particles. Ever since the discovery of cosmic rays early this century, scientists have debated the origin of these particles and how they can be accelerated to such high speeds. Supernova remnants have long been thought to provide the high energy component, but the evidence has been lacking until now. The international team of investigators used the satellite to determine that cosmic rays are generated profusely in the remains of the supernova of 1006 AD - which appeared to medieval viewers to be as bright as the Moon - and that they are accelerated to high velocities by an iterative process first suggested by Enrico Fermi in 1949. Using solid-state X-ray cameras, the ASCA satellite records simultaneous images and spectra of X-rays from celestial sources, allowing astronomers to distinguish different types of X-ray emission. The tell-tale clue to the discovery was the detection of two diametrically opposite regions in the rapidly expanding supernova remnant, the debris from the stellar explosion. The two regions glow intensely from the synchrotron radiation produced when fast-moving electrons are bent by a magnetic field. The remainder of the supernova remnant, in contrast, emits ordinary ''thermal'' X-rays from hot gases such as oxygen, neon, and gaseous forms of magnesium, silicon, sulphur, and iron. The cosmic rays appear to be accelerated in the two regions that glow with synchrotron radiation. Charged particles are accelerated to energies of 100 TeV (10 14 electron volts) in the turbulent aftermath of the supernova explosion shock wave. In the picture first proposed by Fermi in 1949, many cosmic particles are trapped inside the supernova remnant, bouncing around and continually gaining speed in repeated encounters with the shock front. This process probably occurs in other 'young' supernova remnants too. There is estimated to be a supernova explosion in our Milky Way galaxy about once every 30 years. The ASCA satellite was launched from Kagoshima Space Center, Japan aboard a Japanese M-3S-II rocket on 20 February 1993

  8. Riddle of depleted uranium

    International Nuclear Information System (INIS)

    Hussein, A.S.

    2005-01-01

    Depleted Uranium (DU) is the waste product of uranium enrichment from the manufacturing of fuel rods for nuclear reactors in nuclear power plants and nuclear power ships. DU may also results from the reprocessing of spent nuclear reactor fuel. Potentially DU has both chemical and radiological toxicity with two important targets organs being the kidney and the lungs. DU is made into a metal and, due to its availability, low price, high specific weight, density and melting point as well as its pyrophoricity; it has a wide range of civilian and military applications. Due to the use of DU over the recent years, there appeared in some press on health hazards that are alleged to be due to DU. In these paper properties, applications, potential environmental and health effects of DU are briefly reviewed

  9. Riddle of the sands

    Energy Technology Data Exchange (ETDEWEB)

    Rolheiser, P

    1998-09-01

    A geological model of the Alberta landscape during the period stretching from about 110 million to 100 million years ago during the Cretaceous period when dinosaurs roamed the earth, was sketched. Today, the region contains the Cold Lake oil sands deposit. Imperial Oil began large-scale production at Cold Lake in 1985. The formations within the area are the source of almost half of Imperial Oil`s daily crude oil production and account for one in every 20 barrels of oil produced daily in Canada. The bitumen is produced using cyclic steam stimulation where steam is injected at high pressure into the underground reservoir, fracturing the sandstone and heating the bitumen it holds to thin it so that it can then flow through well bores to the surface. Conventional geological theory suggested that the Cold Lake reservoir was the remains of a prehistoric river delta. In 1994, Imperial Oil established a Cold Lake sequence stratigraphy project to verify this theory. This highly complex project involves volumes of geophysical well-log data from the 2,500 wells at Cold Lake, core samples cut from more than 600 of these wells and microscopic fossilized remains of 100-million-year-old flora extracted from the core samples, and seismic information. The interpreted data helps to create a three-dimensional model of the reservoir`s structure and help define its boundaries. Results have shown that the Cold Lake deposit was created from at least 13 intersecting river beds. Each of the rivers flowed for a few hundred thousand years and deposited sands of varying quality in different layers and patterns. The oil came about 40 million years later after the plant and animal materials containing hydrogen and carbon were broken down by heat and pressure to form oil. 1 fig.

  10. 78 FR 6399 - Overseas Security Advisory Council (OSAC) Meeting Notice; Closed Meeting

    Science.gov (United States)

    2013-01-30

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... proprietary commercial information that is privileged and confidential, and will discuss law enforcement... protection of U.S. business information overseas. For more information, contact Marsha Thurman, Overseas...

  11. 76 FR 65318 - Overseas Security Advisory Council (OSAC) Meeting Notice; Closed Meeting

    Science.gov (United States)

    2011-10-20

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... U.S. business information overseas. For more information, contact Marsha Thurman, Overseas Security...

  12. 78 FR 25521 - Overseas Security Advisory Council (Osac) Meeting Notice

    Science.gov (United States)

    2013-05-01

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... U.S. business information overseas. For more information, contact Marsha Thurman, Overseas Security...

  13. 76 FR 4987 - Overseas Security Advisory Council (OSAC) Meeting Notice

    Science.gov (United States)

    2011-01-27

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... U.S. business information overseas. For more information, contact Marsha Thurman, Overseas Security...

  14. 77 FR 3320 - Overseas Security Advisory Council (OSAC) Meeting Notice

    Science.gov (United States)

    2012-01-23

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... U.S. business information overseas. For more information, contact Marsha Thurman, Overseas Security...

  15. 78 FR 45286 - Overseas Security Advisory Council (OSAC) Meeting Notice Closed Meeting

    Science.gov (United States)

    2013-07-26

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... protection of U.S. business information overseas. For more information, contact Marsha Thurman, Overseas...

  16. 77 FR 27110 - Overseas Security Advisory Council (OSAC) Meeting Notice; Closed Meeting

    Science.gov (United States)

    2012-05-08

    ... that the meeting will be closed to the public. The meeting will focus on an examination of corporate... commercial information that is privileged and confidential, and will discuss law enforcement investigative... U.S. business information overseas. For more information, contact Marsha Thurman, Overseas Security...

  17. Skiediklis bulių spermos kriokonservavimui pagal lietuvišką technologiją

    OpenAIRE

    Pileckas, Vidmantas

    2003-01-01

    LGCK (laktozė – 10,5 g, glicerolis – 5 cm3, kiaušinio trynys – 15 cm3, natrio citratas – 0,2 g, bidistiliuotas vanduo – 100 cm3) skiediklis padidina tiesiai judančių spermatozoidų skaičių, absoliutų gyvybingumą (S) ir gyvybingumą (r) atitinkamai 20,5%, 24,6% ir 13,6% (P < 0,05), lyginant su kontroliniu skiedikliu LGK (laktozė – 11,5 g, glicerolis – 5 cm3, kiaušinio trynys – 30 cm3, bidistiliuotas vanduo – 100 cm3). Spermosano PPK dozės 50 ir 100 tūkst. v.v. / 100 cm3 spermatozoidų judrumą pad...

  18. Metallation of N-allenylpyrroles by superbase reagents. Synthesis of new N-substituted pyrroles

    International Nuclear Information System (INIS)

    Tarasova, O.A.; Brandsma, L.; Verkrajsse, Kh.D.; Mal'kina, A.G.; Trofimov, B.A.

    1996-01-01

    Metallation of N-allenylpyrrole by BuLi-Et 2 O (THP), BuLi-t-BuOK-THP superbases and reactions of carbanions formed with different electrophilic agents have been studied. Fundamental data on mutual influence of allene group and pyrrole ring have been obtained. Alpha-proton features the highest acidity and it is the first one to be replaced by metal. In BuLi excess (more than 3-fold) in ether or in BuLi-t-BuOK-THP system a through metallation of allene group occurs. New pyrroles functionally substituted in allene chain have been prepared. 19 refs.; 3 tabs

  19. Pharmacokinetics and pharmacodynamics of antibiotics in biofilm infections of Pseudomonas aeruginosa in vitro and in vivo

    DEFF Research Database (Denmark)

    Hengzhuang, Wang; Høiby, Niels; Ciofu, Oana

    2014-01-01

    Although progress on biofilm research has been obtained during the past decades, the treatment of biofilm infections with antibiotics remains a riddle. The pharmacokinetic (PK) and pharmacodynamic (PD) profiles of an antimicrobial agent provide important information helping to establish an effici......Although progress on biofilm research has been obtained during the past decades, the treatment of biofilm infections with antibiotics remains a riddle. The pharmacokinetic (PK) and pharmacodynamic (PD) profiles of an antimicrobial agent provide important information helping to establish...

  20. Symposium on the Nature of Science—Streaming Video Archive

    Science.gov (United States)

    Oddone – Welcome Mark Ratner – Nano 201: A Gentle Introduction to Nanotechnology and Nanoscience Marsha Physical Sciences Neil Kelleher – How a Chemist Needs Computer Science, Biology, and Engineering to Push – Incorporating Nanotechnology into the Curriculum (streamed session not available) Rich Marvin – Using

  1. STS-46 TCDT Slideware Training and Photo Session

    Science.gov (United States)

    1992-01-01

    The crew of STS-46, Commander Loren J. Shriver, Pilot Andrew M. Allen, Payload Specialist Franco Malerba, Mission Specialists Jeffrey A. Hoffman, Franklin R. Chang-Diaz, Claude Nicollier, and Marsha S. Ivins are seen introducing themselves and discussing the mission during a photo session. The crew then answers questions from the press.

  2. Here to Stay: A Teacher's 46-Year Journey with Accountability in One School Context

    Science.gov (United States)

    Stefanski, Angela J.

    2016-01-01

    This narrative study explores accountability and care in the stories of an exceptional teacher, Marsha Ethridge, who taught more than 46 years in one low-socioeconomic community. While there has been an abundance of research related to teachers' stories of accountability conducted in the last 20 years, much of it reflects accountability imposed on…

  3. Role of the Absorbing Area in Chaotic Synchronization

    DEFF Research Database (Denmark)

    Maistrenko, Yu.L.; Maistrenko, V.L.; Popovich, A.

    1998-01-01

    When two identical chaotic oscillators interact, one or more intervals of coupling parameters generally exist in which the synchronized state is weakly stable, and its basin of attraction is riddled with holes that are repelled from it. The paper discusses the role of the absorbing area for the e......When two identical chaotic oscillators interact, one or more intervals of coupling parameters generally exist in which the synchronized state is weakly stable, and its basin of attraction is riddled with holes that are repelled from it. The paper discusses the role of the absorbing area...

  4. The electroweak symmetry breaking riddle

    International Nuclear Information System (INIS)

    Altarelli, G.

    2010-01-01

    I present a concise review of the Higgs problem which plays a central role in particle physics today. The Higgs of the minimal Standard Model is so far just a conjecture that needs to be verified or discarded at the LHC. Probably the reality is more complicated. I will summarize the motivation for New Physics that should accompany or even replace the Higgs discovery and a number of its possible forms that could be revealed by the LHC. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  5. 'It sounds like a riddle'

    DEFF Research Database (Denmark)

    Rasmussen, M.V.; Rasmussen, Mikkel Vedby

    2004-01-01

    of this emerging research programme on risk arguing that it offers a way to overcome the debate about whether to apply a 'broad' or 'narrow' concept of security; a debate which is stifling the discipline's ability to appreciate the 'war on terrorism' as an example of a new security practice. Discussing the nature......A research programme on 'reflexive security' is emerging, as a number of students of international security are applying sociological insights of 'risk society' to understand new discourses and practices of security. This research note maps the current achievements and future challenges...... of strategy in a risk environment, the paper outlines the consequences for applying the concept of reflexive rationality to strategy. Doing so, I address some of the concerns on how to study 'reflexive security' previously raised by Shlomo Griner in Millennium....

  6. Story Telling and Riddle Games

    DEFF Research Database (Denmark)

    Marchetti, Emanuela

    2011-01-01

    This paper presents the initial phase of a field study, conducted to study social interaction mediated through objects as a learning practice in museums. The guided tour (highly regarded by museum staff) was selected as a starting point to understand how interaction and learning are entangled bet...

  7. Reconstruction: Meltdown in the Midst of Beauty

    African Journals Online (AJOL)

    denise

    This stir of memory led me to write down my story. ... beauty of courage, time, and deep listening, as examined through the experiences of fear of the new and of my .... Suzy and Marsha, the two studio teachers and long term .... I turn my attention to the video camera and think, ..... Psychology & Psychotherapy, 1(1), 56-64.

  8. Buli. Mater. Sci., Vol. 10, No. 4, July 1988, pp. 367-372. (C

    Indian Academy of Sciences (India)

    Mater. Sci., Vol. 10, No. 4, July 1988, pp. 367-372. (C) Printed in India. Studies on iron-chromium redox storage system. SH PAWAR, R D MADHALE, P S PATIL and CD LOKHANDE. Department of Physics, Shivaji University, Kolhapur 416 004, India. Abstract. The performance of the redox storage battery based on the Fe-Cr ...

  9. Buli. Mater. Sci., Vol. 20, No. 2, April 1997, pp. 247-257. (C

    Indian Academy of Sciences (India)

    Synthesis of spodumene and spodumene-zirconia composite ... were prepared using aqueous sol-gel method employing lithium formate, aluminium formate, ... synthesis and the processing of spodumene using different precursor compounds.

  10. Buli. Mater. Sci., Vol. 22, No. 5, August 1999, pp. 927-931. G

    Indian Academy of Sciences (India)

    be 214 eV. Photoelectrochemical (PEC) investigations were carried out using cell configuration n-CdInS/1M. NaOH + 1 M NaS + 1 M S/C. Using Butler model, the optical band gap and minority carrier diffusion length. (L) were found to be 2:22 eV and 007 um, respectively. Gartner's model was used to calculate the minority.

  11. Breaking Away From the Male Stereotype of a Specialist: Gendered Language Affects Performance in a Thinking Task

    Directory of Open Access Journals (Sweden)

    Marlene Kollmayer

    2018-06-01

    Full Text Available This experimental online-survey study investigated if different written language forms in German have an effect on male bias in thinking. We used answers to the specialist riddle as an indicator for male bias in mental representations of expertise. The difficulty of this thinking task lies in the fact that a gender-unspecified specialist is often automatically assumed to be a man due to gender stereotypes. We expected that reading a text in gender-fair language before processing the specialist riddle helps readers achieve control over automatically activated gender stereotypes and thus facilitates the restructuring and reinterpretation of the problem, which is necessary to reach the conclusion that the specialist is a woman. We randomly assigned 517 native German speakers (68% women to reading a text on expertise written either in gender-fair language or in masculine generics. Subsequently, participants were asked to solve the specialist riddle. The results show that reading a text in gender-fair language before processing the riddle led to higher rates of answers indicating that the specialist is a women compared to reading a text in masculine generics (44% vs. 33% in women and men regardless of their self-stereotyping concerning agency and communion. The findings indicate that reading even a very short text in gender-fair language can help people break their gender-stereotype habit and thus reduce male bias in thinking. Our research emphasizes the importance of using gender-fair language in German-language texts for reducing gender stereotypes.

  12. Solving the riddle of interglacial temperatures over the last 1.5 million years with a future IPICS "Oldest Ice" ice core

    Science.gov (United States)

    Fischer, Hubertus

    2014-05-01

    The sequence of the last 8 glacial cycles is characterized by irregular 100,000 year cycles in temperature and sea level. In contrast, the time period between 1.5-1.2 million years ago is characterized by more regular cycles with an obliquity periodicity of 41,000 years. Based on a deconvolution of deep ocean temperature and ice volume contributions to benthic δ18O (Elderfield et al., Science, 2012), it is suggested that glacial sea level became progressively lower over the last 1.5 Myr, while glacial deep ocean temperatures were very similar. At the same time many interglacials prior to the Mid Brunhes event showed significantly cooler deep ocean temperatures than the Holocene, while at the same time interglacial ice volume remained essentially the same. In contrast, interglacial sea surface temperatures in the tropics changed little (Herbert et al., Science,2010) and proxy reconstructions of atmospheric CO2 using δ11B in planktic foraminifera (Hönisch et al., Science, 2009) suggest that prior to 900,000 yr before present interglacial CO2 levels did not differ substantially from those over the last 450,000 years. Accordingly, the conundrum arises how interglacials can differ in deep ocean temperature without any obvious change in ice volume or greenhouse gas forcing and what caused the change in cyclicity of glacial interglacial cycles over the Mid Pleistocene Transition. Probably the most important contribution to solve this riddle is the recovery of a 1.5 Myr old ice core from Antarctica, which among others would provide an unambiguous, high-resolution record of the greenhouse gas history over this time period. Accordingly, the international ice core community, as represented by the International Partnership for Ice Core Science (IPICS), has identified such an 'Oldest Ice' ice core as one of the most important scientific targets for the future (http://www.pages.unibe.ch/ipics/white-papers). However, finding stratigraphically undisturbed ice, which covers this

  13. Synthesis of Polyfunctional Diorganomagnesium and Diorganozinc Reagents through In Situ Trapping Halogen-Lithium Exchange of Highly Functionalized (Hetero)aryl Halides in Continuous Flow.

    Science.gov (United States)

    Ketels, Marthe; Ganiek, Maximilian A; Weidmann, Niels; Knochel, Paul

    2017-10-02

    We report a halogen-lithium exchange performed in the presence of various metal salts (ZnCl 2 , MgCl 2 ⋅LiCl) on a broad range of sensitive bromo- or iodo(hetero)arenes using BuLi or PhLi as the exchange reagent and a commercially available continuous-flow setup. The resulting diarylmagnesium or diarylzinc species were trapped with various electrophiles, resulting in the formation of polyfunctional (hetero)arenes in high yields. This method enables the functionalization of (hetero)arenes containing highly sensitive groups such as an isothiocyanate, nitro, azide, or ester. A straightforward scale-up was possible without further optimization. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Cyber indicators of compromise: a domain ontology for security information and event management

    Science.gov (United States)

    2017-03-01

    heuristics, mapping, and detection. CybOX is aimed at supporting a broad range of important cyber security domains to include [31]: • Digital...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE CYBER INDICATORS OF COMPROMISE: A DOMAIN ONTOLOGY FOR SECURITY INFORMATION AND...Distribution is unlimited. CYBER INDICATORS OF COMPROMISE: A DOMAIN ONTOLOGY FOR SECURITY INFORMATION AND EVENT MANAGEMENT Marsha D. Rowell

  15. Deafness and the Riddle of Identity

    Science.gov (United States)

    Davis, Lennard J.

    2007-01-01

    In the past, much discrimination against deaf people was based on the assumption that they were in fact people without language--that is, dumb. "Dumb" carried the sense of being not only mute but also stupid, as in a "dumb" animal. The status of deaf people has changed in important ways, as deaf activists and scholars have reshaped the idea of…

  16. The riddles of rock and roll

    NARCIS (Netherlands)

    L.J.M. d' Anjou (Leo)

    2003-01-01

    textabstractRock and roll has often been equated with rebellion. The genre, though, is just a form of popular music and many of the important players in the game of promoting it were, like the saying goes, only in it for the money. As a rule, music like that will be supportive of the social order

  17. The Riddle Of The Sphinx Answered

    DEFF Research Database (Denmark)

    Brier, Søren

    2014-01-01

    is to construct an ontology and anthropology that can argue in a consistent way for how true knowledge of the world is possible. This is done by combining phenomenology and realism through a semiotic pragmaticist wholeness philosophy. It also includes existential and spiritual aspects of human reality...

  18. Energy becomes riddle for particle physics

    CERN Multimedia

    Nancy, J

    2003-01-01

    Assuming Einstein's theory of gravity is correct, dark energy must be present in the universe. Physicist's attempts to use quantum field theory to find the amount of dark energy present though, have been very unsuccessful (1/2 page).

  19. The riddle of the sphinx redux.

    Science.gov (United States)

    Shayman, James A

    2010-05-01

    Understanding the mechanisms of glucocorticoid-mediated inhibition of inflammation has been challenging. This is particularly true with regard to the development of drugs that mimic the anti-inflammatory benefits of steroids while avoiding the untoward metabolic effects. Förster et al. report that the inhibition of stress-induced mesangial-cell apoptosis by dexamethasone is mediated by sphingosine-1-phosphate. These findings identify alternative pathways whereby the anti-inflammatory mechanisms of glucocorticoids can be probed.

  20. Solving quantum riddles with neutron scattering

    Energy Technology Data Exchange (ETDEWEB)

    Fobes, David M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Janoschek, Marc [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-16

    Quantum materials exhibit a rich landscape of highly-degenerate quantum states that are widely regarded to hold vast potential for future applications, ranging from power management and transmission, to platforms for quantum computation, to novel versatile sensors and electronics. A key to realizing the promise of future applications is to identify the fundamental energy scales that control the emergence of such quantum states and their properties.

  1. Giant Condyloma Acuminatum: A Surgical Riddle

    Directory of Open Access Journals (Sweden)

    Shukla

    2016-08-01

    Full Text Available Giant condyloma acuminatum (GCA commonly known as Buschke-Lowenstein tumor (BLT is a rare sexually transmitted disease, which is always preceded by condyloma accuminata and linked to human papillomavirus (HPV. Most commonly affected sites are male and female genitalia, anal and perianal regions. Giant condyloma acuminatum is well-known as slow growing but locally destructive with a high rate of recurrence and increased frequency of malignant transformation. Surgical management is considered to be the best among all the options.

  2. Human Performance: Psychological and Physiological Sex Differences (A Selected Bibliography)

    Science.gov (United States)

    1980-02-01

    Sons, 1977. 6 15. Horn, J, L. Human abilities: A review of research and theory in the early 1970’s. Annual Review of Psychology. 1976, 27^, 437...Mother-Infant Interaction, Howard A. Moss. 149. Sex of Parent X Sex of Child: Socioemotional Development, Micheal Lewis and Marsha Weinraub. 165...C. Thomas, 1971. Contents: Biology of Sex Differences. 3. Psychological Sex Differences. 12. Freudian Theory of Feminine Development. 43. The

  3. Non-Lethal Weapons and Evolving Fundamentals of 21st Century Warfare

    National Research Council Canada - National Science Library

    Kuhn, James M

    2005-01-01

    In complex contingency operations of the twenty-first century, the battlespace is riddled with mission ambiguity, extreme conditions, and determined enemies deeply embedded within the local population...

  4. Use of Class Facebook Groups to Disseminate Evidence-Based Study Tips

    Directory of Open Access Journals (Sweden)

    Gina J Ryan

    2017-09-01

    Full Text Available Objective: The purpose of this preliminary project was to determine the effectiveness of college administrators using Facebook® (FB to disseminate information on study methods. Innovation: Eleven study tips in the format of riddles were posted in class FB groups as memes with links that lead to the riddle answers. Between 3.2-39.7% of students clicked on the links that accessed riddle answers. In a survey, 53.8% of respondents found the memes at least somewhat useful and 57.6% reported that they somewhat liked, liked, or liked them a lot. The average score on a study method knowledge assessment increased from 50% to 64%. Critical Analysis: The ratings of usefulness and likeability varied. However, students’ knowledge about the topic increased. Administrators considering using FB to share academic advice should post sparingly, begin posting when groups are initially formed and post early during the academic term. Conflict of Interest We declare no conflicts of interest or financial interests that the authors or members of their immediate families have in any product or service discussed in the manuscript, including grants (pending or received, employment, gifts, stock holdings or options, honoraria, consultancies, expert testimony, patents and royalties.   Type: Note  

  5. Peranan Lingkungan Eksternal Internal Terhadap Kinerja Industri Kecil Batik di Kabupaten Bangkalan

    Directory of Open Access Journals (Sweden)

    Yustina Chrismardani

    2008-06-01

    Full Text Available The performance of every kind of industry always related to external-internal environment. Based on that subject, this research aimed to analyze the influences of external environment factors (buyers, suppliers, techology and government and internal environment factors (marketing, finance and production to the performance of small business of batik in Bangkalan. The population of this research was the small business’s manager or owner in Kecamatan Tanjung Buli Kabupaten Bangkalan. The sample was 42 batik’s manager or owner, taken in 3 villages. The result of this research was : buyers, suppliers, technology, marketing and production had the significant influences to the small business’s performance; and marketing had the biggest influence to the small businesss’s performance.

  6. High-Reynolds Number Viscous Flow Simulations on Embedded-Boundary Cartesian Grids

    Science.gov (United States)

    2016-05-05

    AFRL-AFOSR-VA-TR-2016-0192 High- Reynolds Number Viscous Flow Simulations on Embedded-Boundary Cartesian Grids Marsha Berger NEW YORK UNIVERSITY Final...TO THE ABOVE ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY) 30/04/2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) High- Reynolds 4. TITLE AND...SUBTITLE High- Reynolds Number Viscous Flow Simulations on Embedded-Boundary Cartesian Grids 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-13-1

  7. China's Quest for Security in the Post-Cold War World

    National Research Council Canada - National Science Library

    Kim, Smauel

    1996-01-01

    China's security behavior, riddled with contradictions and paradoxes, seemed made to order for challenging scholars and policymakers concerned about the shape of things to come in post-Cold War international life...

  8. Spasmodic Dysphonia

    Science.gov (United States)

    ... in Children Hoarseness Taking Care of Your Voice Teachers: Take Care of Your Voice News Sargent research ... crack the riddle of spasmodic dysphonia Wall Street Journal ( 10/31/2016 ) More News Have a question? ...

  9. Auditory Processing Disorder (For Parents)

    Science.gov (United States)

    ... role. Auditory cohesion problems: This is when higher-level listening tasks are difficult. Auditory cohesion skills — drawing inferences from conversations, understanding riddles, or comprehending verbal math problems — require heightened auditory processing and language levels. ...

  10. Detection of bearing defects in three-phase induction motors using ...

    Indian Academy of Sciences (India)

    The results of various studies show that bearing problems ... methods for indication of these faults by use of stator current measurement (Kliman & Stein. 1990 ..... Riddle J 1955 Ball bearing maintenance (Norman, OK: Univ. of Oklohama Press).

  11. The Sphinx's Riddle: Life and Career Cycles.

    Science.gov (United States)

    Burack, Elmer H.

    1984-01-01

    Career cycles should be considered apart from life cycles, even though the two are interrelated. This essay examines five theories about life and career cycles, and offers insights into their limitations and potential uses. (JB)

  12. Kyshtym riddle: possible kind of the accident

    International Nuclear Information System (INIS)

    Ballereau, P.

    1988-01-01

    It can been postulated from varied rumors, soviet testimonies, analysis of radioecological russian publications that a serious radiological accident occurred in late 1957 - early 1958 in the Oural mountains. Isotopic ratio 90 Sr/ 137 Cs in the environment following the accident was abnormally high. Several types of accidents has been postulated; the more credible event is an explosion in a storage tank containing dried high activity wastes and NH 4 N0 3 , from which 137 Cs had been extracted [fr

  13. STS-46 'blue' shift crewmembers look up from work on OV-104's flight deck

    Science.gov (United States)

    1992-01-01

    STS-46 'blue' shift crewmembers look up from checklist procedures to have their picture taken on the forward flight deck of Atlantis, Orbiter Vehicle (OV) 104. Seated at the commanders station (left) is Pilot Andrew M. Allen with Italian Payload Specialist Franco Malerba positioned in front of the center console and European Space Agency (ESA) Mission Specialist seated at the pilots station (right). MS Marsha S. Ivins is in the interdeck access hatch at the right bottom corner of the photo.

  14. Methodological debates in human rights research: a case study of human trafficking in South Africa

    NARCIS (Netherlands)

    Vigneswaran, D.

    2012-01-01

    Debates over human trafficking are riddled with methodological dilemmas. Agencies with vested interests in the anti-trafficking agenda advance claims about numbers of victims, level of organized trafficking and scale of exploitation, but with limited data and using questionable techniques. Skeptics,

  15. Single-molecule sequencing and optical mapping yields an improved genome of woodland strawberry (Fragaria vesca) with chromosome-scale contiguity

    Science.gov (United States)

    Although draft genomes are available for most agronomically important plant species, the majority are incomplete, highly fragmented, and often riddled with assembly and scaffolding errors. These assembly issues hinder advances in tool development for functional genomics and systems biology. Here we ...

  16. 76 FR 59160 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Robotics...

    Science.gov (United States)

    2011-09-23

    ... Production Act of 1993--Robotics Technology Consortium, Inc. Notice is hereby given that, on July 27, 2011... seq. (``the Act''), the Robotics Technology Consortium (``RTC'') has filed written notifications... Machining, Longmont, CA; Carnegie Robotics LLC, Pittsburgh, PA; Embry-Riddle Aeronautical University...

  17. Terapia conductual dialéctica

    OpenAIRE

    Gempeler, Juanita

    2008-01-01

    Introducción: Un importante aporte de la terapia cognoscitivo-comportamental al área clínica es la terapia conductual dialéctica (TCD), desarrollada a finales de los años noventa por la psiquiatra Marsha Linehan, como respuesta a las dificultades en el tratamiento del trastorno de personalidad limítrofe (TPL). Se destaca su carácter integrador, pues se basa en principios conductuales y cognoscitivos e incorpora elementos del zen. Es un tratamiento desarrollado y evaluado con mujeres que no só...

  18. Partial Synchronization in a System of Coupled Logistic Maps

    DEFF Research Database (Denmark)

    Taborov, A. V.; Maistrenko, Y. L.; Mosekilde, Erik

    2000-01-01

    which total synchronization tone-cluster dynamics) breaks down to give way to two- and three-cluster dynamics, and follow the subsequent transformations of the various asynchronous periodic, quasiperiodic and chaotic states. Different forms of riddling of the basins of attraction for the fully...

  19. Characterization of sand lenses embedded in tills

    DEFF Research Database (Denmark)

    Kessler, Timo Christian; Klint, K.E.S.; Nilsson, B.

    2012-01-01

    Tills dominate large parts of the superficial sediments on the Northern hemisphere. These glacial diamictons are extremely heterogeneous and riddled with fractures and lenses of sand or gravel. The frequency and geometry of sand lenses within tills are strongly linked to glaciodynamic processes...

  20. Ambiguous Intimacy

    DEFF Research Database (Denmark)

    Houmøller, Kathrin

    2015-01-01

    relations and intimacy is riddled with inevitability and precarity. Here, it is argued, intimacy is ambiguous: allowed and resisted, longed for and feared - simultaneously encompassing practices of closeness and distance, connecting and disconnecting. To make a life in this particular place sometimes...

  1. Fragmentation of wall rock garnets during deep crustal earthquakes

    NARCIS (Netherlands)

    Austrheim, Håkon; Dunkel, Kristina G.; Plümper, Oliver; Ildefonse, Benoît; Liu, Yang; Jamtveit, Bjørn

    2017-01-01

    Fractures and faults riddle the Earth's crust on all scales, and the deformation associated with them is presumed to have had significant effects on its petrological and structural evolution. However, despite the abundance of directly observable earthquake activity, unequivocal evidence for seismic

  2. Preparation, characterization and electrical study of gum arabic/ZnO ...

    Indian Academy of Sciences (India)

    ductive properties.11–16 Semiconducting ZnO nanoparticles. (ZnO-NPs) have some unique ... the dielectric studies of ZnO-doped nanocomposites with polymers, e.g. ..... C A, Riddle B, Weil C M and Krupka J 1998 IEEE Trans. Dielectr. Electr.

  3. Remediation of an acidic mine spoil: Miscanthus biochar and lime amendment affects metal availability, plant growth and soil enzymatic activity

    Science.gov (United States)

    Biochar is proposed as an amendment for mine spoil remediation; however, its effectiveness at achieving this goal remains unclear. Miscanthus (Miscanthus giganteus) biochar was tested for potentially improving acidic mine spoil (pH < 3; Formosa mine near Riddle, Oregon) health conditions by sequeste...

  4. La Terapia Dialéctico Conductual para el tratamiento del Trastorno Límite de la Personalidad.

    OpenAIRE

    Matilde Elices; Soledad Cordero

    2011-01-01

    La Terapia Dialéctico Conductual (TDC) ha sido creada por la Dra. Marsha Linehan, para el tratamiento de pacientes con intentos suicidas recurrentes y diagnóstico de Trastorno Limite de la Personalidad (TLP). Es un modelo terapéutico perteneciente a la “tercera ola” en psicoterapias cognitivas, puesto que se basa en las ciencias del comportamiento e incluye elementos de Mindfulness y de la filosofía dialéctica. En la actualidad la TDC es el tratamiento con mayor evidencia empírica para el TLP...

  5. Crystallographic characterization of divalent organosamarium compound (C5H5)2Sm(THF)2

    International Nuclear Information System (INIS)

    Jagannatha Swamy, S.

    2002-01-01

    The single pot reaction between SmX 2 (X = Cl - , I - ) and BuLi in THF at -40 degC, followed by the addition of C 5 H 5 - Na + results in a dark red solution. Leaving the concentrated reaction mixture at -25 degC for two days in a deep freezer results in the formation of the crystals of the compound, (C 5 H 5 ) 2 ; Sm(THF) 2 . The compound is insoluble in any solvent and it has been characterized by conventional methods. The crystals are monoclinic with space group C2/c, and a = 13.416(1), b = 9.644(1), c = 14.129(2) pm, β109.873(9) 0 and z = 4 for ρcalcd = 1.64 g cm -3 . Least squares refinement on the basis of 1804 observed reflections has led to a final R value of 0.037 and R w = 0.054. (author)

  6. Identical synchronization of coupled Rossler systems

    DEFF Research Database (Denmark)

    Yanchuk, S.; Maistrenko, Y.; Mosekilde, Erik

    1999-01-01

    Analyzing the transverse stability of low periodic orbits embedded in the synchronized chaotic state for a system of two coupled Rössler oscillators, we obtain the conditions for synchronization and determine the coupling parameters for which riddled basins of attraction may arise. It is shown how...

  7. Implementing Participatory Water Management : Recent Advances in Theory, Practice, and Evaluation

    NARCIS (Netherlands)

    Von Korff, Y.; Daniell, K.A.; Moellenkamp, S.; Bots, P.W.G.; Bijlsma, R.M.

    2012-01-01

    Many current water planning and management problems are riddled with high levels of complexity, uncertainty, and conflict, so-called “messes” or “wicked problems.” The realization that there is a need to consider a wide variety of values, knowledge, and perspectives in a collaborative decision

  8. Implementing participatory water management : Recent advances in theory, practice, and evaluation

    NARCIS (Netherlands)

    Von Korff, Y.; Daniell, K.A.; Moellenkamp, S.; Bots, P.W.G.; Bijlsma, R.M.

    2012-01-01

    Many current water planning and management problems are riddled with high levels of complexity, uncertainty, and conflict, so-called “messes” or “wicked problems.” The realization that there is a need to consider a wide variety of values, knowledge, and perspectives in a collaborative decision

  9. Assessment: A Military Methodology in Need of an Overhaul

    Science.gov (United States)

    2014-03-01

    certain ingredients and the amount of each to use by developing a recipe that puts them together and hopefully produces a culinary masterpiece...Engineering, a Masters of Aerospace Science from Embry-Riddle Aeronautical University and a Master of Arts in Global Studies from Kings College, London.

  10. Gamifying Navigation in Location-Based Applications

    DEFF Research Database (Denmark)

    Nadarajah, Stephanie Githa; Overgaard, Benjamin Nicholas; Pedersen, Peder Walz

    2017-01-01

    Location-based games entertain players usually by interactions at points of interest (POIs). Navigation between POIs often involve the use of either a physical or digital map, not taking advantage of the opportunity available to engage users in activities between POIs. The paper presents riddle s...

  11. Desynchronization of chaos in coupled logistic maps

    DEFF Research Database (Denmark)

    Maistrenko, Yu.; Maistrenko, V. L.; Popovych, O.

    1999-01-01

    When identical chaotic oscillators interact, a state of complete or partial synchronization may be attained in which the motion is restricted to an invariant manifold of lower dimension than the full phase space. Riddling of the basin of attraction arises when particular orbits embedded in the sy...

  12. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 1. The Riddle of the Apparently Hollow Himalaya. Ramesh Chander. General Article Volume 3 Issue 1 January 1998 pp 21- ... Author Affiliations. Ramesh Chander1. Department of Earth Sciences, University of Roorkee, Roorkee 247 667, India.

  13. "It's Just a Disability" or Is It?: Stigma, Psychological Needs, and Educational Outcomes in African American Adolescents with Learning-Related Disabilities

    Science.gov (United States)

    Kizzie, Karmen Tamika

    2009-01-01

    The purpose of this dissertation project was to examine the extent to which the special education context, riddled with labeling and teasing, affected the motivation, academic self-concept, grades, and academic achievement of African American adolescents with learning-related disabilities. This dissertation research is situated within two…

  14. Polygon Properties: What Is Possible?

    Science.gov (United States)

    Rodrigue, Paulette R.; Robichaux, Rebecca R.

    2010-01-01

    Sorting shapes and solving riddles develop and advance children's geometric thinking and understanding while promoting mathematical communication, cooperative learning, and numerous representations. This article presents a brief summary of how children develop an understanding of the properties of geometric shapes as well as a description of the…

  15. Could mini black holes provide a 'theory of everything'?

    CERN Multimedia

    Gribbin, J

    1990-01-01

    A Soviet astrophysicist is claiming that the Earth and other astronomical bodies may be riddled with mini black holes - objects smaller than atoms but with masses perhaps greater than planets. These could be responsible for a variety of phenomena inc the rings of Saturn (1/2 page).

  16. What sugar next? Dimerization of sphingolipid glycosyltransferases

    NARCIS (Netherlands)

    van Meer, G.

    2001-01-01

    One of the great riddles of glycobiology is the function of the glycosphingolipids. Their vital role is clear from the fact that the lack only of subsets of glycosphingolipids results in premature death (1). Hundreds of glycosphingolipids populate the surface of mammalian cells. These may serve a

  17. Sphingosine in plants--more riddles from the Sphinx?

    Science.gov (United States)

    Islam, M Nurul; Jacquemot, Marie-Pierre; Coursol, Sylvie; Ng, Carl K-Y

    2012-01-01

    • Sphingolipids are emerging as important mediators of cellular and developmental processes in plants, and advances in lipidomics have yielded a wealth of information on the composition of plant sphingolipidomes. Studies using Arabidopsis thaliana showed that the dihydroxy long-chain base (LCB) is desaturated at carbon position 8 (d18:1(Δ8)). This raised important questions on the role(s) of sphingosine (d18:1(Δ4)) and sphingosine-1-phosphate (d18:1(Δ4)-P) in plants, as these LCBs appear to be absent in A. thaliana. • Here, we surveyed 21 species from various phylogenetic groups to ascertain the position of desaturation of the d18:1 LCB, in order to gain further insights into the prevalence of d18:1(Δ4) and d18:1(Δ8) in plants. • Our results showed that d18:1(Δ8) is common in gymnosperms, whereas d18:1(Δ4) is widespread within nonseed land plants and the Poales, suggesting that d18:1(Δ4) is evolutionarily more ancient than d18:1(Δ8) in Viridiplantae. Additionally, phylogenetic analysis indicated that the sphingolipid Δ4-desaturases from Viridiplantae form a monophyletic group, with Angiosperm sequences falling into two distinct clades, the Eudicots and the Poales. • We propose that efforts to elucidate the role(s) of d18:1(Δ4) and d18:1(Δ4)-P should focus on genetically tractable Viridiplantae species where the d18:1 LCB is desaturated at carbon position 4. © 2011 The Authors. New Phytologist © 2011 New Phytologist Trust.

  18. Dinosaur Tracks, Erosion Marks and Midnight Chisel Work (But No Human Footprints) in the Cretaceous Limestone of the Paluxy River Bed, Texas.

    Science.gov (United States)

    Milne, David H.; Schafersman, Steven D.

    1983-01-01

    Creationists claim that human footprints coexist with those of dinosaurs in Cretaceous limestone exposed in the Paluxy riverbed near Glen Rose, Texas. Analysis of photos shows that the features in question are not human footprints and that creationist documentation/analysis of the prints is riddled with omissions, misrepresentations,…

  19. An Interpretation of Two Oromo Folklore Genres Integrated to ...

    African Journals Online (AJOL)

    The purpose of this study was to analyze and interpret the meanings of two selected folklore genres namely: riddle and pastoral song portrayed in primary Oromo language student text books integrated to enhance the language skills, knowledge, attitude and cultural values of the children. Qualitative method was employed ...

  20. Why can't China clean up its act?

    NARCIS (Netherlands)

    P.P.M.A.R. Heugens (Pursey)

    2017-01-01

    textabstractWinston Churchill once described the Soviet Union as 'a riddle wrapped in a mystery inside an enigma.’ Modern China is a very different story. By definition, the workings of the world’s largest economy (by purchasing power parity) can’t really be hidden from view nearly as easily.

  1. A big, fizzling collider (or, hold that boson)

    CERN Multimedia

    Overbye, Dennis

    2009-01-01

    "The biggest, most expensive physics machine in the world is riddled with thousands of bad electrical connections. Many of the magnets meant to whiz high-energy subatomic particles around a 17-mile, or 27 kilometer, underground racetrack in Switzerland have mysteriously lost their ability to operate at hight energies" (1 page)

  2. Reading, Writing, and "Rhythmetics" for the Verbally Gifted.

    Science.gov (United States)

    Pilon, A. Barbara

    The monograph presents a variety of language arts teaching ideas for use with gifted students. Teachers are encouraged to expose children to much literature including poetry, folk tales, riddles, fairy tales, "pourquoi" tales, myths and legends, fantasy, science fiction, and biographies and autobiographies. The document offers the SIMMER theory of…

  3. Sol T. Plaatje's paremiological quest: A common humanity in cultural ...

    African Journals Online (AJOL)

    2018-03-19

    Mar 19, 2018 ... Indeed, critical or scholarly inquiry into two of Plaatje's multilingual publications, namely, Diane tsa Secoana le Maele a Sekgooa a a ... to promote teaching young Batswana and English people appropriate pronuncia- ... myths, folk tales, stories, and riddles (Possa and Makgopa 1–2), seems to lend itself.

  4. Transformations Encouraged by Story Telling: Middle Eastern Adult Learners' Experiences Abroad

    Science.gov (United States)

    Nguyen, Shelbee R.

    2014-01-01

    Professionals in the field of adult and higher education recognize the path into any learning community is riddled with complexities of life exigencies. This author states that he found "light at the end of the tunnel" in an experiential, transformative study abroad course in Spanish language and culture. Transformative learning abroad…

  5. The Implications of Feyerabend's Epistemological Approach for Educational Research Methods

    Science.gov (United States)

    Ghadikolaei, Elham Shirvani; Sajjadi, Seyed Mahdi

    2015-01-01

    Epistemology is defined as theory of knowledge and the ways of achieving it. Epistemology is research questions of the possibility of knowledge and the riddle of knowledge. Epistemology and methodology despite being interconnected are inseparable and are not reducible from each other. In addition, their relationship is direct, meaning that…

  6. Research Blog

    NARCIS (Netherlands)

    Jautze, K.J.

    2014-01-01

    Welcome to my personal research blog. I'm a PhD candidate from the Netherlands who has an interest in language and literature. In the project The Riddle of Literary Quality my colleagues and I explore the assumption that formal characteristics play a role in the aesthetic appreciation of novels. In

  7. Automating Finance

    Science.gov (United States)

    Moore, John

    2007-01-01

    In past years, higher education's financial management side has been riddled with manual processes and aging mainframe applications. This article discusses schools which had taken advantage of an array of technologies that automate billing, payment processing, and refund processing in the case of overpayment. The investments are well worth it:…

  8. Ivins examines Destiny with the processing team in the SSPF

    Science.gov (United States)

    1999-01-01

    In the Space Station Processing Facility, Marsha Ivins, a mission specialist on the STS-98 crew, inspects the U.S. Laboratory with members of the laboratory's processing team. The laboratory module, considered the centerpiece of the International Space Station (ISS), has been named 'Destiny' in honor of its prominent role in the world's largest science and technology effort. It is planned for launch aboard Space Shuttle Endeavour on the sixth ISS construction flight currently targeted for March 2000. From left to right are Ivins, Danny Whittington (face not visible), Melissa Orozco, Jerry Hopkins, and Suzanne Fase.

  9. The resources of Mars for human settlement

    Science.gov (United States)

    Meyer, Thomas R.; Mckay, Christopher P.

    1989-01-01

    Spacecraft exploration of Marshas shown that the essential resources necessary for life support are present on the Martian surface. The key life-support compounds O2, N2, and H2O are available on Mars. The soil could be used as radiation shielding and could provide many useful industrial and construction materials. Compounds with high chemical energy, such as rocket fuels, can be manufactured in-situ on Mars. Solar power, and possibly wind power, are available and practical on Mars. Preliminary engineering studies indicate that fairly autonomous processes can be designed to extract and stockpile Martian consumables.

  10. Facebook and Twitter For Seniors For Dummies

    CERN Document Server

    Collier, Marsha

    2010-01-01

    A fun and easy social media guide for the over-55 set. People over 55 were the fastest-growing user group on Facebook in the first half of 2009, and they're flocking to Twitter at a faster rate than their under-20 grandchildren. From basic information about establishing an Internet connection to rediscovering old friends, sharing messages and photos, and keeping in touch instantly with Twitter, this book by online expert Marsha Collier helps seniors jump right into social media.: Seniors are recognizing the communication possibilities of Facebook and Twitter and are signing up in record number

  11. A Church with the Poor – Lessons From Scripture and From ...

    African Journals Online (AJOL)

    The church has an essential role to play in communities riddled with poverty, disease, and despair. Communities in informal-settlement areas suffer a great deal. Churches in these communities are often small and have few means for alleviating poverty. In the Bible, the community of God is a community of love. Although ...

  12. Kontserdipeegel : ERSO, Nordic Voices ja NYYD Ensemble / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    1999-01-01

    22. sept. Estonia kontserdisaalis toimunud ERSO kontserdist. Kavas Debussy "Fauni pärastlõuna", R.Straussi Oboekontsert ja F.Mendelssohni 4. sümfoonia. 24. sept. Estonia kontserdisaalis toimunud ans. Nordic Voices kontserdist. ETV suures stuudios toimunud multimeediaetendusest. Kavas M.Nymani "Letters, Riddles & Writs" ja L.Andriesseni "M is for Man, Music, Mozart"

  13. Paving the Road for Student Success: Building a Case for Integrated Strategic Planning from Pre-K to Post-Doc

    Science.gov (United States)

    Kealey, Jarrett; Peterson, Renee; Thompson, Angela; Waters, Kristin

    2015-01-01

    The road from prekindergarten (pre-K) to post-doctoral (post-doc) work is riddled with potholes, detours, u-turns, and construction zones. National education initiatives such as No Child Left Behind, the Common Core, Race to the Top, Performance-Based Funding, College Readiness and Completion Acts, and Post-Graduate Gainful Employment Reports…

  14. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 7. Teaching Chemistry through Riddles. Mala Das Sharma. Classroom Volume 9 Issue 7 July 2004 pp 74-76. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/009/07/0074-0076. Author Affiliations.

  15. Three Cheers for the Red, White, and Blue!

    Science.gov (United States)

    Instructor, 1983

    1983-01-01

    This package of patriotic learning activities refers to historic tales about colonial days, Black history, and the contributions of the states to America's wealth and history. Poems, skits, riddles about states and presidents, and a play featuring mock presidential interviews are included. A Save-the-Statue-of-Liberty project is noted. (PP)

  16. Quality Assurance in Large Scale Online Course Production

    Science.gov (United States)

    Holsombach-Ebner, Cinda

    2013-01-01

    The course design and development process (often referred to here as the "production process") at Embry-Riddle Aeronautical University (ERAU-Worldwide) aims to produce turnkey style courses to be taught by a highly-qualified pool of over 800 instructors. Given the high number of online courses and tremendous number of live sections…

  17. Ethnographic Research, Local Power Brokers and the Political ...

    African Journals Online (AJOL)

    Present-day scholars have critically examined the nature and dynamics of indirect rule in Africa and have found it to be riddled with contradictions and ambiguities. Colonial officers were often accused of imposing colonial structures on local people in the name of tradition. Native Authorities (NAs), for instance, were seen as ...

  18. Reconstructing the Past as a Means of Rationalizing the Present: A Study of Kazuo Ishiguro’s The Remains of The Day (1989

    Directory of Open Access Journals (Sweden)

    Mohamed Fathi Helaly Khalaf

    2017-05-01

    Full Text Available The postwar world period was riddled with rapid changes at the different levels. Many people felt they were not able to come to terms with such ongoing changes and had to find a way to coexist with the status-quo. Postmodernism looks upon man as a social being that should learn how to adapt himself to whatever situation by whatever means available. Ishiguro’s novels are written in an expanded humanistic tradition. They are stories dealing with human relationship. They are narratives centering on the working of consciousness and the unconsciousness of the human mind. Ishiguro is concerned with reworking of the past from a late twentieth century perspective. The purpose of this study is to trace the postmodern aspects in The Remains of The Day through the life and character of Stevens and his relationships with the people that he has lived with. Stevens struggles to come to term with his present through telling stories and anecdotes of his past life. The novel depicts the role that memories can play in reconstructing the past events so that the present can be meaningful in some way from a postmodern standpoint. As a postwar British individual, the protagonist of the novel tries to practice suppression over his emotions at the personal level as well as the professional level to construct a new identity. Stevens appears torn between memories of the past and the representation of the present. He is suffering from an identity crisis and striving to create a meaningful present for himself. As a postmodern man, Stevens has to struggle at different levels. He is leading a life riddled with inconsistencies and contradictions. He can’t feel at home with the surrounding world as he is always busy trying to achieve some perfection that is not attainable in a world riddled with conflicts and struggle.

  19. Strengths and weaStrengths and Weaknesses of Ola Rotim's ...

    African Journals Online (AJOL)

    Besides using the play to address Nigeria's numerous problems at independence, Rotimi also brings in a lot of changes in the original Greek play. He dispenses with the chorus, in their place; he relies on the narrator and chiefs of Kutuje. He replaces Greek chants with African songs; he employs proverbs, riddles and other ...

  20. The Coffee-Milk Mixture Problem Revisited

    Science.gov (United States)

    Marion, Charles F.

    2015-01-01

    This analysis of a problem that is frequently posed at professional development workshops, in print, and on the Web--the coffee-milk mixture riddle--illustrates the timeless advice of George Pólya's masterpiece on problem solving in mathematics, "How to Solve It." In his book, Pólya recommends that problems previously solved and put…

  1. John Rawls' original position: a model for socio-political retooling of ...

    African Journals Online (AJOL)

    The life prospects of all in society are, in part, determined by the socio-political situation in currency. It is, therefore, pertinent that the basic structure of society should be organized on a fair set of principles allowing for social justice. Nigeria, however, riddled with issues of large scale corruption, ethnicity, constitution and the ...

  2. Differential Modulation of Performance in Insight and Divergent Thinking Tasks with tDCS

    Science.gov (United States)

    Goel, Vinod; Eimontaite, Iveta; Goel, Amit; Schindler, Igor

    2015-01-01

    While both insight and divergent thinking tasks are used to study creativity, there are reasons to believe that the two may call upon very different mechanisms. To explore this hypothesis, we administered a verbal insight task (riddles) and a divergent thinking task (verbal fluency) to 16 native English speakers and 16 non-native English speakers…

  3. Darwin's Revolution in Thought: An Illustrated Lecture. Teaching Guide and Videotape.

    Science.gov (United States)

    Gould, Stephen Jay

    "Darwin's Revolution in Thought" is Stephen Jay Gould's definitive treatise on Charles Darwin. This 50-minute classroom edition videotaped lecture is structured in the form of a paradox and three riddles about Darwin's life. Each is designed to shed light on one of the key features of the theory of natural selection, its philosophical…

  4. Is Hypoxia common despite oxygen treatment in the Acute Medical ...

    African Journals Online (AJOL)

    The delivery of oxygen in an acute Admissions Unit is always (often) riddled with difficulties. While most patients do get oxygen at some point of time it is often uncontrolled and inappropriate. This reflects inadequate and untrained staffing in the very busy Medical Units. We did a small study on 30 random acute admissions ...

  5. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. M D Deshpande. Articles written in Resonance – Journal of Science Education. Volume 9 Issue 4 April 2004 pp 50-60 General Article. The No-Slip Boundary Condition in Fluid Mechanics - 1.The Riddle of Fluid Sticking to the Wall in Flow · Sandeep Prabhakara ...

  6. Universality for the parameter-mismatching effect on weak synchronization in coupled chaotic systems

    International Nuclear Information System (INIS)

    Lim, Woochang; Kim, Sang-Yoon

    2004-01-01

    To examine the universality for the parameter-mismatching effect on weak chaotic synchronization, we study coupled multidimensional invertible systems such as the coupled Henon maps and coupled pendula. By generalizing the method proposed in coupled one-dimensional (1D) noninvertible maps, we introduce the parameter sensitivity exponent δ to measure the degree of the parameter sensitivity of a weakly stable synchronous chaotic attractor. In terms of the parameter sensitivity exponents, we characterize the effect of the parameter mismatch on the intermittent bursting and the basin riddling occurring in the regime of weak synchronization. It is thus found that the scaling exponent μ for the average characteristic time (i.e., the average interburst time and the average chaotic transient lifetime) for both the bubbling and riddling cases is given by the reciprocal of the parameter sensitivity exponent, as in the simple system of coupled 1D maps. Hence, the reciprocal relation (i.e., μ = 1/δ) seems to be 'universal', in the sense that it holds in typical coupled chaotic systems of different nature

  7. The Nature of the Electron

    Science.gov (United States)

    Lincoln, Don

    2016-01-01

    Winston Churchill once said of Russia that it was a riddle wrapped in mystery inside an enigma. Were the British Bulldog a physicist, he might have been talking of something other than our Slavic comrades. He might have been talking about an electron. This article covers the more modern representations of the electron. A brief reminder of the…

  8. How doth the little busy bee: unexpected metabolism.

    Science.gov (United States)

    Barros, L Felipe; Sierralta, Jimena; Weber, Bruno

    2015-01-01

    Brain energy metabolism powers information processing and behavior, much as electricity powers a computer. However, a recent study in insects suggests that this relationship is more interesting, causally linking aggressive behavior to energetics. These findings may also shed new light on aerobic glycolysis, a long-standing riddle of human brain physiology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. B S Shylaja

    Indian Academy of Sciences (India)

    What is Transit? B S Shylaja · More Details Fulltext PDF. Volume 18 Issue 5 May 2013 pp 412-427 General Article. The Ladies' Diary - Puzzles and Riddles from the Era of Newton! B S Shylaja · More Details Fulltext PDF. Volume 20 Issue 4 April 2015 pp 352-359 General Article. From Navigation to Star Hopping: Forgotten ...

  10. Ramesh Chander

    Indian Academy of Sciences (India)

    ... written in Resonance – Journal of Science Education. Volume 3 Issue 1 January 1998 pp 21-26 General Article. The Riddle of the Apparently Hollow Himalaya ... Volume 4 Issue 5 May 1999 pp 52-60 General Article. The Debate About the Age of the Earth · Ramesh Chander · More Details Fulltext PDF. Volume 4 Issue 7 ...

  11. Historical texts from the Swahili coast (part 2)

    OpenAIRE

    Nurse, Derek

    2012-01-01

    Historical texts from the Swahili coast (Swahili-English): Upper Pokomo Elwana, Mwiini Bajuni Pate Amu, She la Matondoni, Mwani Asili ya Mphokomu Fumo Liongo A story. Proverbs and riddles Mashairi Saidi Haji talking about poetry. Kiteko, a story Verse by MA Abdulkadir, Women`s political songs. An old woman reminisces, Mbaraka Msuri, a hadithi. Ngano A story.

  12. Lichenological studies in Puerto Rico: history and current status

    Science.gov (United States)

    Joel A. Mercado-Diaz; Eugenio Santiago-Valentin

    2010-01-01

    European scientists initiated lichenology in Puerto Rico in the 19th century. Activity of the discipline increased notably on the island during the first three decades of the 20th century, primarily by the field explorations and publications of the New York Botanical Garden scientists and associates (A. A. Heller, N. L. and E. G. Britton, L. W. Riddle), and by the work...

  13. Algunos aspectos de los Aenigmata Symphosii: título, autor y relación con la Historia Apollonii regis Tyri

    Directory of Open Access Journals (Sweden)

    María José Muñoz Jiménez

    1987-12-01

    Full Text Available Symphosius is not the name of the author of the collection of a hundred riddles contained in the Anthologia Latina; in fact, the original title of the collection might well be the Aenigmata Symphosii by an anonymous author. Notwithstanding, it is possible that this author and that of the Historia Apollonii regis Tyri are one and the same person.

  14. A beginner's guide to mathematical logic

    CERN Document Server

    Smullyan, Raymond M

    2014-01-01

    Combining stories of great philosophers, quotations, and riddles with the fundamentals of mathematical logic, this new textbook for first courses in mathematical logic was written by the subject's creative master. Raymond Smullyan offers clear, incremental presentations of difficult logic concepts with creative explanations and unique problems related to proofs, propositional logic and first-order logic, undecidability, recursion theory, and other topics.

  15. The Future of Reading: Don't Worry. It Might Be Better than You Think

    Science.gov (United States)

    Green, John

    2010-01-01

    It is a fun parlor game to speculate about what the future of books will look like. The author wonders whether stories will be read on screens and supplemented with gaming, illustration, video, and multimedia riddles. In this essay, the author shares his vision of the future of reading and describes what he learned from writing a story based on…

  16. Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach).

    Science.gov (United States)

    Ikehara, Kenji

    2016-01-26

    It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event-the establishment of the first genetic code encoding [GADV]-amino acids-as a juncture for the results obtained from the two approaches.

  17. Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach

    Directory of Open Access Journals (Sweden)

    Kenji Ikehara

    2016-01-01

    Full Text Available It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event—the establishment of the first genetic code encoding [GADV]-amino acids—as a juncture for the results obtained from the two approaches.

  18. Parents of children with chronic health problems: programs of nursing research and their relationship to developmental science.

    Science.gov (United States)

    Miles, Margaret Shandor

    2003-01-01

    This review identified nurse researchers and research teams that have current programs of research focused on parents and parenting of children with chronic health problems. Researchers were included if they had at least five publications since 1990, with at least three of these articles first-authored. These programs of research were critiqued from a developmental science perspective. Multiple methods were used for the search, including examination of previous review articles, hand search of journals, online computer searches, and review of the curriculum vitae of authors. Seven programs of research were identified. Two programs of research focused on childhood cancer--Ida M. Martinson et al. and Marsha H. Cohen. Three programs of research used a noncategorical approach encompassing a variety of childhood chronic conditions--Katherine A. Knafl and Janet A. Deatrick, Sharon O. Burke, and Ann Garwick. One program focused primarily on parents of children with Down syndrome and disabilities--Marsha Van Riper--and another on parents of infants with a variety of chronic health problems--Margaret S. Miles and Diane Holditch-Davis. Diverse theories and conceptual frameworks were used, and most had some focus on ecological systems that might affect parents and parenting. Many used a family perspective and included fathers. Still broader aspects of the family and community ecology and the health care were not generally included. Few examined the bidirectionality of the relationship between the child and aspects of the child's illness and parental responses. There was variability in the extent to which ethnicity and socioeconomic status were considered. Studies provide important insight into the responses of parents and their parenting of children with chronic health problems. The studies provide a sound base for continuing to build a developmentally sensitive body of knowledge related to parents and parenting of the child with chronic health problems.

  19. Solubilization of Phenol Derivatives in Polymer Micelles Formed by Cationic Block Copolymer

    Directory of Open Access Journals (Sweden)

    Irma Fuentes

    2017-01-01

    Full Text Available The aggregation of cationic block copolymers formed by polystyrene (PS and poly(ethyl-4-vinylpyridine (PS-b-PE4VP was studied in aqueous solution. Diblock copolymers of PS and poly(4-vinylpyridine were synthesized by sequential anionic polymerization using BuLi as initiator. Subsequently, the 4-vinylpyridine units were quaternized with ethyl bromide to obtain cationic PS-b-PE4VP block copolymers with different quaternization degree. The self-aggregation of cationic block copolymers was studied by fluorescence probing, whereas the morphology and size of polymer micelles were determined by transmission electronic microscopy. Results indicate that spherical micelles with sizes lower than 100 nm were formed, whereas their micropolarity decreases with increasing quaternization degree. The partition of phenols between the micellar and aqueous phase was studied by using the pseudo-phase model, and the results show that the partition coefficients increase with increasing length of the side alkyl chain and are larger for star micelles. These results are discussed in terms of three-region model.

  20. Diazadienes in chemistry of lanthanides: latest view on old ligands. Synthesis, structure and properties of complexes {[(R)CNC6H3Pr2i]2}Lu(THF)2(μ-Cl)2Li(THF2 (R=CH3, CH2)

    International Nuclear Information System (INIS)

    Makhrova, T.V.; Fukin, G.K.; Cherkasov, A.V.; Trifonov, A.A.

    2008-01-01

    Reaction of dianion derivative [DADLi 2 ] (DAD -1,4-bis(2,6-diisopropylphenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene) prepared in situ by the reduction of corresponding DAD by the excess of metal lithium in THF with anhydrous LuCl 3 (1:1) results in the formation of the metal cyclic complex {[(R)CNC 6 H 3 Pr 2 i ] 2 }Lu(THF) 2 (μ-Cl) 2 Li(THF) 2 (1) containing the fragment N-C(Me)=C(Me)-N. DAD Treatment by two equivalents BuLi in the mixture ether-hexane (20 Deg C) results in the activation of the C-H bond of methyl substitutes at imine carbon. By the reaction of dilithium derivative [DAD - 2 H Li 2 ] formed in situ with LuCl 3 in THF the complex {[(CH 2 )CNC 6 H 3 Pr 2 i ] 2 }Lu(THF) 2 (μ-Cl) 2 Li(THF) 2 (2) with diamide ligand N-C(=CH 2 )-C(=CH 2 )-N was prepared. Structures of 1 and 2 complexes have been established by X-ray structure analysis [ru

  1. POMEGRANATE IN WRITTEN AND SPOKEN LITERATURE / AZERBAYCAN SÖZLÜ VE YAZILI EDEBIYATINDA NAR

    Directory of Open Access Journals (Sweden)

    Dr. Mehmet İSMAİL

    2008-10-01

    Full Text Available According to the scientists punica’s native land isAzerbaijan. This fruit grows up in many countries allover the world and there are lots of kinds of it inAzerbaijan. This is a survey of pomegranate as it featuresin the folklore (tale, legend, myth, proverb, riddle, curse,praise, expression, folk song of Azerbaijan. And alsosome examples of folk-literature is added in which punicaexists.

  2. [Dialectical behavior therapy approaches with disruptive behavior disorders].

    Science.gov (United States)

    Stadler, Christina; Manetsch, Madleina; Vriends, Noortje

    2016-11-01

    Disruptive behaviour disorders comprise the diagnosis conduct disorder (CD) and in adults the diagnosis antisocial personality disorder (APD). CD is seen as a difficult-to-treat disorder with a high risk for persistent behavioral problems. In addition, CD is seen as the precursor to antisocial personality disorder (Kretschmer et al., 2014). Dialectical behavior therapy (DBT) was originally developed by Marsha Linehan (1991) for the treatment of borderline personality disorder, but because of the core deficits in emotion regulation in disruptive behavior disorders, DBT is also increasingly being recommended for the treatment of CD and APD. This review presents DBT adaptions for the forensic setting and for the treatment of CD/APD. Clinical implications are discussed.

  3. Mission Command: The Historical Roots of Mission Command in the US Army

    Science.gov (United States)

    2015-05-21

    Bauer, Zachary Taylor: Soldier, Planter, Statesman, of the Old Southwest (Baton Rouge, LA : Louisiana State University Press, 1985), 1. General...Battle of Buena Vista , he observed the battle from so close that his coat ended up riddled with holes from grape shot.25 General Taylor created a...1846 report to Colonel Joseph Totten he describes his observations of the battle of Palo Alto and Resaca De La Palma. Scarritt served temporarily

  4. Cellular and Porous Materials Thermal Properties Simulation and Prediction

    CERN Document Server

    Öchsner, Andreas; de Lemos, Marcelo J S

    2008-01-01

    Providing the reader with a solid understanding of the fundamentals as well as an awareness of recent advances in properties and applications of cellular and porous materials, this handbook and ready reference covers all important analytical and numerical methods for characterizing and predicting thermal properties. In so doing it directly addresses the special characteristics of foam-like and hole-riddled materials, combining theoretical and experimental aspects for characterization purposes.

  5. Self-sustained Flow-acoustic Interactions in Airfoil Transitional Boundary Layers

    Science.gov (United States)

    2015-07-09

    AFRL-AFOSR-VA-TR-2015-0235 Self-sustained flow-acoustic interactions in airfoil transitional boundary layers Vladimir Golubev EMBRY-RIDDLE...From - To)      01-04-2012 to 31-03-2015 4.  TITLE AND SUBTITLE Self-sustained flow-acoustic interactions in airfoil transitional boundary layers 5a...complementary experimental and numerical studies of flow-acoustic resonant interactions in transitional airfoils and their impact on airfoil surface

  6. Finding clues to the riddle of sex determination in zebrafish

    Indian Academy of Sciences (India)

    ... to instruct retention of the ovarian fate. The mechanism and identity of this instructive signal remain unknown. We hypothesize that sex in zebrafish is a culmination of combinatorial effects of the genome, germ cells and the environment with inputs from epigenetic factors translating the biological meaning of this interaction.

  7. Contribution of Embodiment to Solving the Riddle of Infantile Amnesia

    Directory of Open Access Journals (Sweden)

    Arthur M Glenberg

    2016-01-01

    Full Text Available At least since the late nineteenth century, researchers have sought an explanation for infantile amnesia (IA—the lack of autobiographical memories dating from early childhood—and childhood amnesia (CA, faster forgetting of events up until the age of about seven. Evidence suggests that IA occurs across altricial species, and a number of studies using animal models have converged on the hypothesis that maturation of the hippocampus is an important factor. But why does the hippocampus mature at one time and not another, and how does that maturation relate to memory? Our hypothesis is rooted in theories of embodied cognition, and it provides an explanation both for hippocampal development and the end of IA. Specifically, the onset of locomotion prompts the alignment of hippocampal place cells and grid cells to the environment, which in turn facilitates the ontogeny of long-term episodic memory and the end of IA. That is, because the animal can now reliably discriminate locations, location becomes a stable cue for memories. Furthermore, as the mode of human locomotion shifts from crawling to walking, there is an additional shift in the alignment of the hippocampus that marks the beginning of adult-like episodic memory and the end of CA. Finally, given a reduction in self-locomotion and exploration with aging, the hypothesis suggests a partial explanation for cognitive decline with aging.

  8. DNA Taxonomy - the Riddle of Oxychloë (Juncaceae)

    DEFF Research Database (Denmark)

    Kristiansen, Kim Anker; Cilieborg, Malene Skovsted; Drábková, Lenka

    2005-01-01

    is fatal, but if no voucher exists, bad sequences and bad taxonomy may be forever linked. Previous phylogenetic analyses of rbcL sequences have indicated that the small, south hemisphere, genus Oxychloë (Juncaceae) surprisingly either is embedded within or is a sister group to the Cyperaceae....... This is not in accordance with traditional or current morphological data. By studying five new accessions, representing four species of Oxychloë, and re-examining the two vouchers of O. andina that were used in previous phylogenies, it has been possible to show that these two sequences are erroneous. One is a chimeric...

  9. Constraining the equation of state of neutron stars from binary mergers.

    Science.gov (United States)

    Takami, Kentaro; Rezzolla, Luciano; Baiotti, Luca

    2014-08-29

    Determining the equation of state of matter at nuclear density and hence the structure of neutron stars has been a riddle for decades. We show how the imminent detection of gravitational waves from merging neutron star binaries can be used to solve this riddle. Using a large number of accurate numerical-relativity simulations of binaries with nuclear equations of state, we find that the postmerger emission is characterized by two distinct and robust spectral features. While the high-frequency peak has already been associated with the oscillations of the hypermassive neutron star produced by the merger and depends on the equation of state, a new correlation emerges between the low-frequency peak, related to the merger process, and the total compactness of the stars in the binary. More importantly, such a correlation is essentially universal, thus providing a powerful tool to set tight constraints on the equation of state. If the mass of the binary is known from the inspiral signal, the combined use of the two frequency peaks sets four simultaneous constraints to be satisfied. Ideally, even a single detection would be sufficient to select one equation of state over the others. We test our approach with simulated data and verify it works well for all the equations of state considered.

  10. The Forgotten Insurgency: Is There Hope For Colombia

    Science.gov (United States)

    2005-12-01

    familiar in the current conflicts on-going in Iraq and Afghanistan where weakened states are riddled by insurgencies and violence. In a lecture to...the heels of the period known as La Violencia or “The Violence” which occurred from 1948-1958. This violent period in Colombian history began with...affected.16 The end of La Violencia came in 1958 with the establishment of Frente Nacional (the National Front) where both parties signed an agreement

  11. Phosphine Toxicity: A Story of Disrupted Mitochondrial Metabolism

    Science.gov (United States)

    2016-05-24

    Phosphine and selected metal phosphides. Environ. Health Criteria 73. 5. Reeve, I. 2014. Estimation of exposure to persons in Califor- nia ...Gill. 2011. Aluminum phosphide poisoning: an unsolved riddle. J. Appl. Toxicol. 31: 499– 505 . 9. Lam, W.W., R.F. Toia & J. Casida. 1991. Oxidatively...Trends Biochem. Sci. 35: 505 –513. 43. Turrens, J.F. 2003. Mitochondrial formation of reactive oxy- gen species. J. Physiol. 552: 335–344. 44. Fridovich

  12. Translating conservation genetics into management: Pan-European minimum requirements for dynamic conservation units of forest tree genetic diversity

    OpenAIRE

    Koskela, Jarkko; Lefèvre, François; Schueler, Silvio; Kraigher, Hojka; Olrik, Ditte C.; Hubert, Jason; Longauer, Roman; Bozzano, Michele; Yrjänä, Leena; Alizoti, Paraskevi; Rotach, Peter; Vietto, Lorenzo; Bordács, Sándor; Myking, Tor; Eysteinsson, Thröstur

    2013-01-01

    This paper provides a review of theoretical and practical aspects related to genetic management of forest trees. The implementation of international commitments on forest genetic diversity has been slow and partly neglected. Conservation of forest genetic diversity is still riddled with problems, and complexities of national legal and administrative structures. Europe is an example of a complex region where the dis- tribution ranges of tree species extend across large geographical areas with ...

  13. Ecology and conservation of the maned wolf: introduction

    OpenAIRE

    Consorte-McCrea, A.; Santos, Eliana Ferraz

    2013-01-01

    Wolves are considered controversial figures worldwide: mythical creatures as well as troublemakers, their conservation can polarize extreme views and it often is riddled with conflicts. In recent years much effort has focussed on the discussion of how to conserve large carnivores, such as wolves, while addressing public concerns. The maned wolf, however, has mostly eluded the discussion stage. With its solitary habits and unusual fruit-eating diet, the endangered maned wolf roams the grasslan...

  14. Why can't China clean up its act?

    OpenAIRE

    Heugens, Pursey

    2017-01-01

    textabstractWinston Churchill once described the Soviet Union as 'a riddle wrapped in a mystery inside an enigma.’ Modern China is a very different story. By definition, the workings of the world’s largest economy (by purchasing power parity) can’t really be hidden from view nearly as easily. However, the sheer scale means that certain aspects of that vast market’s workings are still not all that easy to understand.

  15. Make me authentic, but not here: Reflexive struggles with academic identity and authentic leadership

    OpenAIRE

    Tomkins, Leah; Nicholds, Alyson

    2017-01-01

    This article presents a reflexive auto-ethnography of the experience of teaching authentic leadership to MBA students. It traces parallels between the challenges of authentic leadership and the challenges of academic identity work, grounded specifically in the experience of having to teach something one does not fully endorse. Both authentic leadership and academic identity work emerge as struggle – riddled with false starts, best intentions and self-deception, and entwined in the politics of...

  16. Infrastructure procurement skills gap amongst procurement personnel in Nigeria’s public sector

    OpenAIRE

    Mahamadu, A.-M. ed; Manu, P.; Booth, C.; Olomolaiye, P.; Coker, A.; Ibrahim, A. ed; Lamond, J.

    2018-01-01

    Purpose - Procurement of public infrastructure that is fit for purpose partly depends on the competencies of procurement personnel. In many developing countries in Sub-Saharan Africa, including Nigeria, there is a deficit in the quantity and quality of infrastructure and their procurement is further riddled with deficiencies in the capacity of public procuring entities. It is, however, unclear from the extant literature, what are the critical skills development needs of public personnel invol...

  17. Portfolio Diversification in the South-East European Equity Markets

    OpenAIRE

    Zaimovic Azra; Arnaut-Berilo Almira; Mustafic Arnela

    2017-01-01

    Diversification potential enables investors to manage their risk and decrease risk exposure. Good diversification policy is a safety net that prevents a portfolio from losing its value. A well-diversified portfolio consists of different categories of property with low correlations, while highly correlated markets have the feature of low possibilities for diversification. The biggest riddle in the world of investments is to find the optimal portfolio within a set of available assets with limit...

  18. Depositional turbidity currents in diapiric minibasins on the continental slope: Formulation and theory

    OpenAIRE

    Toniolo, Horacio; Lamb, Michael; Parker, Gary

    2006-01-01

    The northern continental slope of the Gulf of Mexico is riddled with numerous subsiding diapiric minibasins bounded by ridges, many but not all of which are connected by channels created by turbidity currents. The region is economically relevant in that many of these diapiric minibasins constitute focal points for the deposition of sand. Some of these sandy deposits in turn serve as excellent reservoirs for hydrocarbons. A better understanding of the "fill and spill" process by which minibasi...

  19. The use of indigenous techniques of communication for language learning: The case of Cameroon

    OpenAIRE

    Ebong, Balbina

    2004-01-01

    This study aimed at determining whether the use of indigenous techniques of communication can have a positive impact on the motivation of the learner of English as a foreign language in Cameroon. By indigenous techniques of communication we mean techniques like role-play, songs, the telling of folktales, riddles and proverbs. This work is intended as a contribution to the search for improvement of student motivation and enthusiasm, whereby they can be more responsive as they participate spont...

  20. Unravelling Starlight

    Science.gov (United States)

    Becker, Barbara J.

    2017-03-01

    1. Introduction; 2. '… the astronomer … must come to the chemist'; 3. The young observer; 4. 'A sudden impulse …'; 5. The riddle of the nebulae; 6. Moving in the inner circle; 7. Stellar motion along the line of sight; 8. A new telescope; 9. Solar observatories; 10. An able assistant; 11. Photographing the solar corona; 12. A scientific lady; 13. Foes and allies; 14. The new astronomy; 15. 'One true mistress'; 16. Conclusion; Appendix; Index.

  1. Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection.

    Science.gov (United States)

    Zablocki, Daniela; Sadoshima, Junichi

    2013-11-08

    A series of studies conducted 20 years ago, documenting the cardiac hypertrophy phenotype and its underlying signaling mechanism induced by angiotensin II (Ang II) and mechanical stress, showed a remarkable similarity between the effect of the Gαq agonist and that of mechanical forces on cardiac hypertrophy. Subsequent studies confirmed the involvement of autocrine/paracrine mechanisms, including stretch-induced release of Ang II in load-induced cardiac hypertrophy. Recent studies showed that the Ang II type 1 (AT1) receptor is also directly activated by mechanical forces, suggesting that AT1 receptors play an important role in mediating load-induced cardiac hypertrophy through both ligand- and mechanical stress-dependent mechanisms.

  2. THE DIMENSIONLESS AGE OF THE UNIVERSE: A RIDDLE FOR OUR TIME

    Energy Technology Data Exchange (ETDEWEB)

    Avelino, Arturo; Kirshner, Robert P., E-mail: aavelino@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, Massachusetts, 02138 (United States)

    2016-09-01

    We present the interesting coincidence of cosmology and astrophysics that points toward a dimensionless age of the Universe H {sub 0} t {sub 0} that is close to one. Despite cosmic deceleration for 9 Gyr and acceleration since then, we find H {sub 0} t {sub 0} = 0.96 ± 0.01 for the ΛCDM model that fits SN Ia data from Pan-STARRS, CMB power spectra, and baryon acoustic oscillations. Similarly, astrophysical measures of stellar ages and the Hubble constant derived from redshifts and distances point to H {sub 0} t ∼ 1.0 ± 0.1. The wide range of possible values for H {sub 0} t {sub 0} realized during cosmic evolution means that we live at what appears to be a special time. This “synchronicity problem” is not precisely the same as the usual coincidence problem , because there are combinations of Ω{sub M} and Ω{sub Λ} for which the usual coincidence problem holds but for which H {sub 0} t {sub 0} is not close to 1.

  3. C. S. Peirce’s Semiotic Answer to the Riddle of Consciousness

    DEFF Research Database (Denmark)

    Brier, Søren

    A scientific explanation of consciousness that is not partially based on phenomenology seems logically impossible. C.S. Peirce’s pragmaticist semiotics attempts to bridge the gap between natural sciences and humanities by combining a phenomenological approach with an evolutionary and realistic...... understanding of nature and society in the development of a new transdisicplinary and evolutionary theory of meaning and logic in a semiotic theory of mind and consciousness. Though a contributor to the development of modern logic and science Peirce, through inventing a semiotics that embraced phenomenology...

  4. RIDDLE: Race and ethnicity Imputation from Disease history with Deep LEarning

    KAUST Repository

    Kim, Ji-Sung; Gao, Xin; Rzhetsky, Andrey

    2018-01-01

    are predictive of race and ethnicity. We used these characterizations of informative features to perform a systematic comparison of differential disease patterns by race and ethnicity. The fact that clinical histories are informative for imputing race

  5. Ken Jacobs and the Perverted Archival Image

    OpenAIRE

    Gonçalo Pablo

    2016-01-01

    This paper analyses two recent works by American filmmaker Ken Jacobs that deal with aspects of remediation. The first is A Tom Tom Chaser, in which Jacobs records the telecine process that transforms the classic silent film Tom, Tom, the Piper’s Son from chemical into electronic media. The film is riddled with poetic turns inviting the audience to rediscover the medial noise hidden by images. Moreover, Jacobs focuses on the moment of transition from a material medium (the film strip) to the ...

  6. Room escape at class: escape games activities to facilitate the motivation and learning in computer science

    OpenAIRE

    Borrego, Carlos; Fernández, Cristina; Blanes, Ian; Robles, Sergi

    2017-01-01

    Real-life room-escape games are ludic activities in which participants enter a room in order to get out of it only after solving some riddles. In this paper, we explain a Room Escape teaching experience developed in the Engineering School at Universitat Autònoma de Barcelona. The goal of this activity is to increase student’s motivation and to improve their learning on two courses of the second year in the Computer Engineering degree: Computer Networksand Information and Security Peer Revi...

  7. Cheat Electricity? The Political Economy of Green Electricity Delivery on the Dutch Market for Households and Small Business

    OpenAIRE

    J. A. M. Hufen

    2016-01-01

    The European Commission’s renewable energy directive introduced a market-based Guarantees of Origin (GO)-trade system that gives consumers the choice of buying “real” green energy. This has been successful, as the market share of Dutch households that buy green energy grew to 64% in 2015. However, societal organizations are dissatisfied with the green energy offered, categorizing it as “cheat” electricity. This article aims to solve this riddle of a successful product created under the GO-tra...

  8. WIS Implementation Study Report. Volume 1. Main Report.

    Science.gov (United States)

    1983-10-01

    Luenberger, Prof. David G. * Stanford University Ries, Dr. Daniel R. * Computer Corporation of America Schill, John Naval Ocean Systems Center Shrier , Dr...Robert E. 43 Kaczmarek, Dr. Thomas S. 45 Klein, Dr. Stanely A. 47 Kramer, Dr. John F. 49 Larsen, Dr. Robert E. 55 Luenberger, Prof. David G. 58...Riddle, Dr. William E. 76 Ries, Dr. Daniel R. 82 Sapp, Mr. John W. 88 Shelley, Mr. Stephen H. 89 Shrier , Dr. Stefan 94 Slusarczuk, Dr. Marko M.G. 96

  9. Emergence and translations of management interests in corporate branding in the Finnish pulp and paper corporations : a study with an actor-network theory approach

    OpenAIRE

    Aspara, Jaakko

    2007-01-01

    The riddle of this Thesis is: How come the management of the Finnish pulp and paper (P&P) corporations became interested in corporate branding around the year 2000? By the Finnish P&P corporations, I refer particularly to the three large P&P corporations based in Finland in 2005: UPM-Kymmene, Stora Enso, and M-Real. By the management, I refer to managers of these corporations including the top managers, i.e. CEOs and executive board members, and even the members of the Boards of Directors. ...

  10. Room escape at class: Escape games activities to facilitate the motivation and learning in computer science

    Directory of Open Access Journals (Sweden)

    Carlos Borrego

    2017-06-01

    Full Text Available Real-life room-escape games are ludic activities in which participants enter a room in order to get out of it only after solving some riddles. In this paper, we explain a Room Escape teaching experience developed in the Engineering School at Universitat Autònoma de Barcelona. The goal of this activity is to increase student’s motivation and to improve their learning on two courses of the second year in the Computer Engineering degree: Computer Networksand Information and Security.

  11. Complicated basins and the phenomenon of amplitude death in coupled hidden attractors

    Energy Technology Data Exchange (ETDEWEB)

    Chaudhuri, Ushnish [Department of Physics, Sri Venkateswara College, University of Delhi, New Delhi 110021 (India); Department of Physics, National University of Singapore, Singapore 117551 (Singapore); Prasad, Awadhesh, E-mail: awadhesh@physics.du.ac.in [Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India)

    2014-02-07

    Understanding hidden attractors, whose basins of attraction do not contain the neighborhood of equilibrium of the system, are important in many physical applications. We observe riddled-like complicated basins of coexisting hidden attractors both in coupled and uncoupled systems. Amplitude death is observed in coupled hidden attractors with no fixed point using nonlinear interaction. A new route to amplitude death is observed in time-delay coupled hidden attractors. Numerical results are presented for systems with no or one stable fixed point. The applications are highlighted.

  12. Venezuelan oil - the unfulfilled promise

    OpenAIRE

    2007-01-01

    Winston Churchill once said that ‘Russia was a riddle wrapped in a mystery inside an enigma.’ One is reminded of these words when approaching the subject of Venezuela’s oil strategy in the last few years. Venezuelan politics, and by implication its economy, have always been product and hostage to oil and the capriciousness of the oil price. A founder member of OPEC, and throughout history a very vocal, and at times vociferous advocate for the rights of the sovereign state against the inte...

  13. Back pain and the resolution of diagnostic uncertainty in illness narratives.

    Science.gov (United States)

    Lillrank, Annika

    2003-09-01

    In this paper I consider 30 Finnish women's written narratives about the process of getting back pain diagnosed. From the beginning of the early discomfort of back pain, the women were sure of its bodily and subjective reality. They struggled repeatedly to be taken seriously, and only after years of medical disparagement did they encounter medical professionals who were able solve the riddle and give it a name, a diagnosis. Since back pain is a baffling problem and challenges the central biomedical epistemology-objective knowledge and measurable findings separate from subjective experience-it allowed the doctors to show a disrespectful attitude toward back pain sufferers. The moral essence of the women's common story was the stigmatizing experience when doctors did not take subjective pain seriously. Instead, doctors' neglectful attitudes became part of the prolonged problem. During the long-lasting uncertainty, women tried multiple coping strategies to ease their lives and developed mental attitudes to endure the pain. Since the protagonists did not give up the lived certainty of back pain they were gradually able to challenge medical uncertainty and to demand a thorough medical examination, and/or through random circumstance they encountered doctors who were willing to take their symptoms seriously. This triggered turning points that immediately or very soon resulted in solving the riddle of the puzzling pain. To be finally diagnosed was a great relief. However, to be taken seriously as a person was considered to be the greatest relief.

  14. Seleucid, Demotic and Mediterranean mathematics versus Chapters VIII and IX of the Nine Chapters: accidental or significant similarities?

    DEFF Research Database (Denmark)

    Høyrup, Jens

    Similarities of geometrical diagrams and arithmetical structures of problems have often been taken as evidence of transmission of mathematical knowledge or techniques between China and “the West”. Confronting on one hand some problems from Chapter VIII of the Nine Chapters with comparable problems...... known from Ancient Greek sources, on the other a Seleucid collection of problems about rectangles with a subset of the triangle problems from Chapter IX, it is concluded, (1) that transmission of some arithmetical riddles without method – not “from Greece” but from a transnational community of traders...

  15. Zopár úvah o dôvtipe a intuícii (Several Considerations on Esprit and Intuition

    Directory of Open Access Journals (Sweden)

    Renáta Kišoňová

    2008-06-01

    Full Text Available This article treats of an esprit and an intuition. What is the role of the esprit in the cognize? In common use means an esprit fast, automatic fixing in a given aspect. The problem of the esprit is related with the problem of the understanding of jokes, riddles, or poetical metaphors. It is also connected with the mathematical cognizance or "sight" in geometry. The speech analyzes several chosen thinkers which attended to enquiries of the esprit or the intuition, e.g. I. Kant, L. Wittgenstein and H. Bergson.

  16. Assessing the geologic and climatic forcing of biodiversity and evolution surrounding the Gulf of California

    Science.gov (United States)

    Dolby, Greer; Bennett, Scott E. K.; Lira-Noriega, Andres; Wilder, Benjamin T.; Munguia-Vega, Adrian

    2015-01-01

    For almost a century the Baja California peninsula (Peninsula), Gulf of California (Gulf), and broader Sonoran Desert region (figure 1) have drawn geologists and biologists alike to study its unique physical and evolutionary processes (e.g., Wittich 1920; Darton 1921; Nelson 1921; Johnston 1924; Beal 1948; Durham and Allison 1960). The challenge remains to untangle the long, intricate, and at times enigmatic geological and climatological histories that have shaped the high levels of endemism and biodiversity observed in the region today (Van Devender 1990; Grismer 2000; Riddle et al. 2000).

  17. THE ROLE OF HOLIDAY IN CHILDREN EDUCATION / ÇOCUK EĞĐTĐMĐNDE BAYRAMLARIN ROLÜ

    Directory of Open Access Journals (Sweden)

    Eldeniz ABBASLI

    2008-05-01

    Full Text Available This article is based on the celebration of the national holidays inAzerbaycan. One of these holidays is "Nevruz". Generally "Nevruz" is thesymbol of coming Spring not only in Azerbaycan but most of the countries of theworld. But in Azerbaycan, people celebratethis holiday traditionally. Here the children, students as well as the little childrenprepare for this celebration with great pleasure. They learn more proverbs,riddles, stories, dances, songs in order to take an active part in the celebration of"Nevruz". Such preparatiopns improve the knowledge of the children.

  18. Bifurcation structures and transient chaos in a four-dimensional Chua model

    Energy Technology Data Exchange (ETDEWEB)

    Hoff, Anderson, E-mail: hoffande@gmail.com; Silva, Denilson T. da; Manchein, Cesar, E-mail: cesar.manchein@udesc.br; Albuquerque, Holokx A., E-mail: holokx.albuquerque@udesc.br

    2014-01-10

    A four-dimensional four-parameter Chua model with cubic nonlinearity is studied applying numerical continuation and numerical solutions methods. Regarding numerical solution methods, its dynamics is characterized on Lyapunov and isoperiodic diagrams and regarding numerical continuation method, the bifurcation curves are obtained. Combining both methods the bifurcation structures of the model were obtained with the possibility to describe the shrimp-shaped domains and their endoskeletons. We study the effect of a parameter that controls the dimension of the system leading the model to present transient chaos with its corresponding basin of attraction being riddled.

  19. Classical and quantum electrodynamics and the B(3) field

    CERN Document Server

    Evans, Myron W

    2001-01-01

    It is well known that classical electrodynamics is riddled with internal inconsistencies springing from the fact that it is a linear, Abelian theory in which the potentials are unphysical. This volume offers a self-consistent hypothesis which removes some of these problems, as well as builds a framework on which linear and nonlinear optics are treated as a non-Abelian gauge field theory based on the emergence of the fundamental magnetizing field of radiation, the B(3) field. Contents: Interaction of Electromagnetic Radiation with One Fermion; The Field Equations of Classical O (3) b Electrodyn

  20. Review of: Ancient Scandinavia: An Archaeological History from the First Humans to the Vikings (Oxford University Press, Oxford, 2016) T. Douglas Price

    DEFF Research Database (Denmark)

    Løvschal, Mette

    2017-01-01

    , barrows and megaliths that still mark the present-day landscape and bear witness to an intriguing prehistory. One of the important factors involved in the discovery of these archaeological remains is the nature of Scandinavian landscapes, riddled as they are with wet marshes, bogs, rivers and flooded......), providing better opportunities for strategic sampling and systematic data storage than in many other regions of Europe. This book draws together the main historical lines in this rich body of archaeological remains from Scandinavian prehistory from the arrival of the first reindeer hunters after the last...

  1. The riddle of the real city : or the dark knowledge of urbanism

    NARCIS (Netherlands)

    Rasch, M.D.; Nijenhuis, Wim

    2017-01-01

    Does our knowledge about city and urban planning have solid ground? Can historical research promote creative thinking? How can we theorise about urban design and architecture in our age of the media? These questions have guided the creation of this multi-layered, richly documented and illustrated

  2. Adapting Dialectical Behavior Therapy for the Treatment of Dissociative Identity Disorder.

    Science.gov (United States)

    Foote, Brad; Van Orden, Kim

    2016-12-31

    Dialectical Behavior Therapy (DBT), created by Marsha Linehan, has been shown to be an effective therapy for the treatment of borderline personality disorder (BPD) and for suicidal and self-harming behavior. Dissociative identity disorder (DID) is a complex post-traumatic disorder which is highly comorbid with BPD, shares a number of clinical features with BPD, and which like BPD features a high degree of suicidality. The DID treatment literature emphasizes the importance of a staged approach, beginning with the creation of a safe therapeutic frame prior to addressing traumatic material; DBT is also a staged treatment, in which behavioral and safety issues are addressed in Stage 1, and trauma work reserved for Stage 2. The authors describe adapting DBT, and especially its techniques for Stage 1 safety work, for work with DID patients. Basic theoretical principles are described and illustrated with a case example.

  3. Artificial neural network application for space station power system fault diagnosis

    Science.gov (United States)

    Momoh, James A.; Oliver, Walter E.; Dias, Lakshman G.

    1995-01-01

    This study presents a methodology for fault diagnosis using a Two-Stage Artificial Neural Network Clustering Algorithm. Previously, SPICE models of a 5-bus DC power distribution system with assumed constant output power during contingencies from the DDCU were used to evaluate the ANN's fault diagnosis capabilities. This on-going study uses EMTP models of the components (distribution lines, SPDU, TPDU, loads) and power sources (DDCU) of Space Station Alpha's electrical Power Distribution System as a basis for the ANN fault diagnostic tool. The results from the two studies are contrasted. In the event of a major fault, ground controllers need the ability to identify the type of fault, isolate the fault to the orbital replaceable unit level and provide the necessary information for the power management expert system to optimally determine a degraded-mode load schedule. To accomplish these goals, the electrical power distribution system's architecture can be subdivided into three major classes: DC-DC converter to loads, DC Switching Unit (DCSU) to Main bus Switching Unit (MBSU), and Power Sources to DCSU. Each class which has its own electrical characteristics and operations, requires a unique fault analysis philosophy. This study identifies these philosophies as Riddles 1, 2 and 3 respectively. The results of the on-going study addresses Riddle-1. It is concluded in this study that the combination of the EMTP models of the DDCU, distribution cables and electrical loads yields a more accurate model of the behavior and in addition yielded more accurate fault diagnosis using ANN versus the results obtained with the SPICE models.

  4. La sphinx décadente: topos et poetique de la transgression

    Directory of Open Access Journals (Sweden)

    Lise Revol-Marzouk

    2012-03-01

    Sphinx to topos and the reader to fatigue. It would, however, omit the ultimate transgression committed by the Hellenic Sphinx: transgression of language, of course, by its riddles, obscure and ambivalent, violating the norms of logic and rhetoric. The decadent Sphinx's sexual provocation is thus accompanied by a textual innovation at all levels, leading the reader in a constant game of poetic transgressions that are as destabilizing as they are seductive. Behind the erotic revival of mystery, a new and unexpected type of language develops that is capable of re-enchanting reality, and with it, all literature.

  5. Batman: En musikalisk berättelse : En analys av filmerna Batman: The Movie, Batman och The Dark Knight

    OpenAIRE

    Bohlin, Benjamin

    2017-01-01

    Syftet med uppsatsen är att analysera hur filmmusiken har använts i Batman: The Movie (1966), Batman (1989) och The Dark Knight (2008). Att se en narrativ användning och beskrivning av Batman samt hur upplevelsen av filmen ändras när man ser den utan musik. Kompositörerna till filmerna är, för Batman: The Movie (1966) Nelson Riddle, till Batman (1989) är det Danny Elfman och till The Dark Knight (2008) är kompositörerna Hans Zimmer och James Newton Howard. Filmerna analyserats från ett mult...

  6. Residue-specific description of non-native transient structures in the ensemble of acid-denatured structures of the all-beta protein c-src SH3

    DEFF Research Database (Denmark)

    Rösner, Heike I; Poulsen, Flemming Martin

    2010-01-01

    -src loop to the third beta-strand, exhibited an apparent helicity of nearly 45%. Furthermore, the RT loop and the diverging turn appeared to adopt non-native-like helical conformations. Interestingly, none of the residues found in transient helical conformations exhibited significant varphi-values [Riddle......Secondary chemical shift analysis has been used to characterize the unfolded state of acid-denatured c-src SH3. Even though native c-src SH3 adopts an all-beta fold, we found evidence of transient helicity in regions corresponding to native loops. In particular, residues 40-46, connecting the n...

  7. Why patients mutilate themselves.

    Science.gov (United States)

    Favazza, A R

    1989-02-01

    Self-mutilation, the deliberate destruction or alteration of body tissue without conscious suicidal intent, occurs in a variety of psychiatric disorders. Major self-mutilation includes eye enucleation and amputation of limbs or genitals. Minor self-mutilation includes self-cutting and self-hitting. The author examines patients' explanations for self-mutilation which frequently focus on religions or sexual themes, and discusses scientific explanations that draw on biological, psychological, social, and cultural theories. Although no one approach adequately solves the riddle of such behaviors, habitual self-mutilation may best be thought of as a purposeful, if morbid, act of self-help.

  8. The global development race and the Samaritan's dilemma

    DEFF Research Database (Denmark)

    Svendsen, Gunnar Lind Haase; Gert Tinggaard, Svendsen

    2008-01-01

    Why has ‘development aid' been donated by so-called developed to under-developed populations since World War II? Using discourse analysis, this article provides partial answers to this riddle. First, we suggest that donor motives may be rooted in an ideology of ‘being good' which, paradoxically......, motivates recipients to be helpless, i.e. a Samaritan's Dilemma. Second, drawing on journal articles from 1960-1970, we test this theory by tracing a global development discourse and ‘goodness ideology' in a Western country like Denmark - a process that was strongly influenced by the agricultural co...

  9. Terapia dialéctico conductual para el trastorno de personalidad límite

    Directory of Open Access Journals (Sweden)

    Irene de la Vega

    2013-06-01

    Full Text Available La terapia dialéctico conductual (TDC es una terapia psicológica de tercera generación desarrollada por Marsha Linehan (1993a, 1993b para tratar específicamente los síntomas característicos del trastorno límite de la personalidad: inestabilidad afectiva, trastorno de identidad, impulsividad y dificultades en las relaciones sociales. La TDC parte de un modelo biosocial del trastorno límite y combina técnicas cognitivo conductuales con aproximaciones zen y budistas basadas en la aceptación de la realidad tal como se presenta. El tratamiento consiste en un entrenamiento en habilidades, psicoterapia individual y atención en crisis y es llevado a cabo por un equipo coordinado de profesionales que ejercen distintas funciones. La TDC cuenta con estudios de eficacia y se está aplicando con éxito a otras poblaciones de pacientes con elevada impulsividad.

  10. In search of a solution to the sphinx-like riddle of GM1.

    Science.gov (United States)

    Ledeen, Robert W; Wu, Gusheng

    2010-12-01

    Among the many glycoconjugates contributing to the sugar code, gangliosides have drawn special attention owing to their predominance as the major sialoglycoconjugate category within the nervous system. However, their occurrence, albeit at lower levels, appears ubiquitous in vertebrate cells and even some invertebrate tissues. Now that over 100 gangliosides have been structurally characterized, their diverse physiological functions constitute a remaining enigma. This has been especially true of GM1, for which a surprising array of functions has already been revealed. Our current research has focused on two areas of GM1 function: (a) signaling induced in neural and immune cells by cross-linking of GM1 in the plasma membrane that leads to activation of TRPC5 (transient receptor potiential, canonical form 5) channels, a process important in neuritogenesis and autoimmune suppression; (b) activation by GM1 of a sodium-calcium exchanger (NCX) in the inner membrane of the nuclear envelope (NE) with resulting modulation of nuclear and cellular calcium. The latter has a role in maintaining neuronal viability, loss of which renders neurons vulnerable to Ca(2+) overload. Pathological manifestations in mutant mice and their cultured neurons lacking GM1 have shown dramatic rescue with a membrane permeable derivative of GM1 that enters the nucleus and restores NCX activity. Nuclear function of GM1 is related to the presence of neuraminidase in the NE, an enzyme that generates GM1 through hydrolysis of GD1a. A different isoform of this enzyme was found in each of the two membranes of the NE.

  11. Riddles of the Sphinx: Titan Science Questions at the End of Cassini-Huygens

    Science.gov (United States)

    Nixon, C. A.; Achterberg, R. K.; Buch, A.; Clark, R. N.; Coll, P.; Flasar, F. M.; Hayes, A. G.; Iess, L.; Lorenz, R. D.; Lopes, R.; Mastroguiseppe, M.; Raulin, F.; Smith, T.; Solomidou, A.; Sotin, C.; Strobel, D. F.; Turtle, E. P.; Vuitton, V.; West, R. A.; Yelle, R.

    2017-02-01

    The paper will describe the outstanding high-level questions for Titan science that are remaining at the end of the Cassini-Huygens mission, compiled by a cross-section of scientists from multiple instrument teams.

  12. Consciousness and C. S. Peirce’s Answer to the Riddle of the Sphinx

    DEFF Research Database (Denmark)

    Brier, Søren

    2016-01-01

    on phenomenology seems logically impossible therefore the many (unsuccessful) attempts to naturalize. C.S. Peirce’s pragmaticist semiotics attempts to bridge the gap between natural sciences and humanities by combining a phenomenological approach with an evolutionary and realistic understanding of nature...... and society in the development of a semiotic theory of mind and consciousness. Though a contributor to the development of modern logic and science Peirce, through inventing a semiotics that embraced phenomenology, tried to heal the split Husserl saw. Philosophy aims primarily at the kind of knowledge...... that gives unity and system to the whole body of human, social and natural basic sciences through a critical examination of the grounds of our convictions, prejudices, and beliefs. Where Husserl wanted to heal the split he observed through his pure phenomenology, Peirce integrated his semiotics with a pure...

  13. Unravelling 21st Century Riddles – Universal Network Visions from a Human Perspective

    NARCIS (Netherlands)

    Baken, N.; Van Belleghem, N.; Van Boven, E.; De Korte, A.

    2006-01-01

    Networks are omnipresent and universal. Mankind, for example, forms a social network. Today, information and communications technology (ICT) exponentially accelerates the interaction between the human nodes of this global social network. In that way, ICT appears to evoke a phase transformation,

  14. The riddles of foehn. Introduction to the historic articles by Hann and Ficker

    Energy Technology Data Exchange (ETDEWEB)

    Seibert, Petra [University of Natural Resources and Life Science Vienna (Austria). Inst. of Meteorology; Vienna Univ. (Austria). Dept. of Meteorology and Geophysics

    2012-12-15

    Two key papers on the topic of foehn are introduced. The first one, published in 1885 by Julius Hann, discusses the history of the 'thermodynamic foehn theory', and the role of the various scientists who contributed to its evolution. Emphasis is placed on the early recognition of important aspects by J.P. Espy which was not properly recognised in Europe at the time of publication (around 1850). Hann's article is very interesting also because it permits insight into the role of social factors for the acceptance of scientific theories, involving two of the most important meteorologists of the 19th century, W. Dove and J. Hann himself. The second paper was published in 1910 by Heinrich Ficker and discusses theories for the process of foehn break-through which are evaluated on the base of Ficker's mesonet in the area of Innsbruck and surroundings. Finally, the most important developments in foehn research in the past 100 years, since the appearance of Ficker's article, are very briefly sketched. (orig.)

  15. Bell's palsy: the answer to the riddle of Leonardo da Vinci's 'Mona Lisa'.

    Science.gov (United States)

    Maloney, W J

    2011-05-01

    The smile of the famed portrait 'The Mona Lisa' has perplexed both art historians and researchers for the past 500 years. There has been a multitude of theories expounded to explain the nature of the model's enigmatic smile. The origin of the model's wry smile can be demonstrated through a careful analysis of both documented facts concerning the portrait--some gathered only recently through the use of modern technology--and a knowledge of the clinical presentation of Bell's palsy. Bell's palsy is more prevalent in women who are either pregnant or who have recently given birth. This paper postulates that the smile of the portrait's model was due to Leonardo da Vinci's anatomically precise representation of a new mother affected by Bell's palsy subsequent to her recent pregnancy.

  16. The Global Development Race and Samaritan's Dilemma

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard; Svendsen, Gunnar Lind Haase

    2008-01-01

    Why has ‘development aid' been donated by so-called developed to under-developed populations since the Second World War? Using discourse analysis, this article provides partial answers to this riddle. First, we suggest that donor motives may be rooted in an ideology of ‘being good', which......, paradoxically, motivates recipients to be helpless - that is, a Samaritan's dilemma. Second, drawing on journal articles published in 1960-70, we test this theory by tracing a global development discourse and ‘goodness ideology' in a Western country such as Denmark - a process that was strongly influenced...... by the agricultural co-operative movement, which sought to export the ‘Danish co-operative model'....

  17. Blogging and Social Media for Mental Health Education and Advocacy: a Review for Psychiatrists.

    Science.gov (United States)

    Peek, Holly S; Richards, Misty; Muir, Owen; Chan, Steven Richard; Caton, Michael; MacMillan, Carlene

    2015-11-01

    We live in a digital age where information can be found instantaneously via the Internet. Studies have shown that consumers search for much of their medical information on the Internet, particularly utilizing blogs and social media platforms. As the mental health field is riddled with misinformation and stigma, this offers a unique opportunity for psychiatrists and mental health professionals to reach a broad audience for mental health education and advocacy. In this review, we discuss the various methods and techniques for blogging and social media. We then review the current recommendations for ethics and professionalism as well as make recommendations to strengthen our guidance in this new and evolving field.

  18. ON CYBERIMMORTALITY

    Directory of Open Access Journals (Sweden)

    ADAM DROZDEK

    2015-09-01

    Full Text Available This article discusses the view of man as software, which leads to a view of personal immortality accomplished by uploading the mind to the computer. The view has been defended by computer scientists (e.g., Moravec, Kurzweil and by theologians (e.g., Polkinghorne. The article argues that true immortality of the mind, or of the pattern of the mind, is riddled with the problem of maintaining personal identity. Moreover, because the preservation of the mind pattern requires a material substrate, the view also assumes that the material world is eternal. This article favors the Platonist-Augustinian view of immortality of the soul understood as a substance.

  19. The neutrino mirror

    International Nuclear Information System (INIS)

    Vannucci, F.

    2003-09-01

    The neutrino is not an elementary particle like others, it is the most stunning of all: the neutrino is undetectable by itself, we have only indirect evidences of its existence, but the neutrino is essential to explain the weak interaction, to understand why matter triumphed over anti-matter just after the Big-bang, or to solve the riddle of the hidden mass of the universe. This book is a popular work dedicated to the neutrino from its discovery in beta decays to the most recent theories such as neutrino oscillations, and via the worldwide experiments dedicated to the study of the neutrinos. (A.C.)

  20. Cracking the Einstein code relativity and the birth of black hole physics

    CERN Document Server

    Melia, Fulvio

    2009-01-01

    Albert Einstein’s theory of general relativity describes the effect of gravitation on the shape of space and the flow of time. But for more than four decades after its publication, the theory remained largely a curiosity for scientists; however accurate it seemed, Einstein’s mathematical code—represented by six interlocking equations—was one of the most difficult to crack in all of science. That is, until a twenty-nine-year-old Cambridge graduate solved the great riddle in 1963. Roy Kerr’s solution emerged coincidentally with the discovery of black holes that same year and provided fertile testing ground—at long last—for general relativity

  1. Towards solving the riddle of forgetting in functional amnesia: recent advances and current opinions.

    Science.gov (United States)

    Staniloiu, Angelica; Markowitsch, Hans J

    2012-01-01

    Remembering the past is a core feature of human beings, enabling them to maintain a sense of wholeness and identity and preparing them for the demands of the future. Forgetting operates in a dynamic neural connection with remembering, allowing the elimination of unnecessary or irrelevant information overload and decreasing interference. Stress and traumatic experiences could affect this connection, resulting in memory disturbances, such as functional amnesia. An overview of clinical, epidemiological, neuropsychological, and neurobiological aspects of functional amnesia is presented, by preponderantly resorting to own data from patients with functional amnesia. Patients were investigated medically, neuropsychologically, and neuroradiologically. A detailed report of a new case is included to illustrate the challenges posed by making an accurate differential diagnosis of functional amnesia, a condition that may encroach on the boundaries between psychiatry and neurology. Several mechanisms may play a role in "forgetting" in functional amnesia, such as retrieval impairments, consolidating defects, motivated forgetting, deficits in binding and reassembling details of the past, deficits in establishing a first person autonoetic connection with personal events, and loss of information. In a substantial number of patients, we observed a synchronization abnormality between a frontal lobe system, important for autonoetic consciousness, and a temporo-amygdalar system, important for evaluation and emotions, which provides empirical support for an underlying mechanism of dissociation (a failure of integration between cognition and emotion). This observation suggests a mnestic blockade in functional amnesia that is triggered by psychological or environmental stress and is underpinned by a stress hormone mediated synchronization abnormality during retrieval between processing of affect-laden events and fact-processing.

  2. Towards Solving the Riddle of Forgetting in Functional Amnesia: Recent Advances and Current Opinions

    Directory of Open Access Journals (Sweden)

    Angelica eStaniloiu

    2012-11-01

    Full Text Available Remembering the past is a core feature of human beings, enabling them to maintain a sense of wholeness and identity and preparing them for the demands of the future. Forgetting operates in a dynamic neural connection with remembering, allowing the elimination of unnecessary or irrelevant information overload and decreasing interference. Stress and traumatic experiences could affect this connection, resulting in memory disturbances, such as functional amnesia. An overview of clinical, epidemiological, neuropsychological and neurobiological aspects of functional amnesia is presented, by preponderantly resorting to own data from patients with functional amnesia. Patients were investigated medically, neuropsychologically and neuroradiologically. A detailed report of a new case is included to illustrate the challenges posed by making an accurate differential diagnosis of functional amnesia, a condition that may encroach on the boundaries between psychiatry and neurology. Several mechanisms may play a role in forgetting in functional amnesia, such as retrieval impairments, consolidating defects, motivated forgetting, deficits in binding and reassembling details of the past, deficits in establishing a first person autonoetic connection with personal events and loss of information. In a substantial number of patients, we observed a synchronization abnormality between a frontal lobe system, important for autonoetic consciousness, and a temporo-amygdalar system, important for evaluation and emotions, which provides empirical support for an underlying mechanism of dissociation (a failure of integration between cognition and emotion. This observation suggests a mnestic blockade in functional amnesia that is triggered by psychological or environmental stress and is underpinned by a stress hormone mediated synchronization abnormality during retrieval between processing of affect-laden events and fact-processing.

  3. Crime, Justice, and Inequality: Oh Canada, Where Art Thou?

    Directory of Open Access Journals (Sweden)

    Walter DeKeseredy

    2013-11-01

    Full Text Available Since Canada’s colonial beginnings, it has become increasingly riddled with classism, racism, sexism, and other damaging outcomes of structured social inequality. In 2006, however, many types of social injustice were turbo-charged under the federal leadership of the Harper government. For example, a recent southern Ontario study shows that less than half of working people between the ages of 25 and 65 have full-time jobs with benefits. The main objective of this paper is to critique the dominant Canadian political economic order and the pain and suffering it has caused for millions of people. Informed by left realism and other progressive ways of knowing, I also suggest some ways of turning the tide.

  4. Meteor head echoes - observations and models

    Directory of Open Access Journals (Sweden)

    A. Pellinen-Wannberg

    2005-01-01

    Full Text Available Meteor head echoes - instantaneous echoes moving with the velocities of the meteors - have been recorded since 1947. Despite many attempts, this phenomenon did not receive a comprehensive theory for over 4 decades. The High Power and Large Aperture (HPLA features, combined with present signal processing and data storage capabilities of incoherent scatter radars, may give an explanation for the old riddle. The meteoroid passage through the radar beam can be followed with simultaneous spatial-time resolution of about 100m-ms class. The current views of the meteor head echo process will be presented and discussed. These will be related to various EISCAT observations, such as dual-frequency target sizes, altitude distributions and vector velocities.

  5. La Terapia Dialéctico Conductual para el tratamiento del Trastorno Límite de la Personalidad.

    Directory of Open Access Journals (Sweden)

    Matilde Elices

    2011-06-01

    Full Text Available La Terapia Dialéctico Conductual (TDC ha sido creada por la Dra. Marsha Linehan, para el tratamiento de pacientes con intentos suicidas recurrentes y diagnóstico de Trastorno Limite de la Personalidad (TLP. Es un modelo terapéutico perteneciente a la “tercera ola” en psicoterapias cognitivas, puesto que se basa en las ciencias del comportamiento e incluye elementos de Mindfulness y de la filosofía dialéctica. En la actualidad la TDC es el tratamiento con mayor evidencia empírica para el TLP, demostrando ser efectiva en la reducción de varios problemas asociados a este trastorno, como ser: autolesiones, intentos de autoeliminación, ideación suicida, desesperanza, depresión y comportamientos asociados a la bulimia. El objetivo de este artículo es desarrollar los fundamentos teóricos y conceptuales básicos sobre los que se construye la TDC, y exponer sus principales directrices de tratamiento. También se establecen las principales diferencias con la terapia cognitivo – conductual standard.

  6. Kahua A';o--A Learning Foundation: Using Hawaiian Language Newspaper Articles for Science and Science Education

    Science.gov (United States)

    Chinn, P. W.; Businger, S.

    2013-12-01

    Kahua A';o, an NSF OEDG project, utilizes Hawaiian language newspaper articles written between 1843 and 1948 in lessons and professional development intended to increase participation of underrepresented Native Hawaiian students in earth science. Guided by sociocultural theories that view learning as experiential and culturally situated, geoscientists (Steven Businger, Scott Rowland, Floyd McCoy, UG student Kelly Lance); Hawaiian translators (M. Puakea Nogelmeier, GRAs Kapomaikai Stone and Iasona Ellinwood); science educators (Pauline Chinn, graduate student Lindsey Spencer), utilize articles to develop place-based meteorology and geology curricula for middle school teachers. Articles are valuable to science and science education: Native Hawaiians are citizen scientists who recorded, interpreted, and communicated findings to potentially critical audiences, while dated, descriptive, eye witness reports provide data on events unrecorded by westerners. Articles reveal Hawaiian intellectual tradition placed great value on environmental knowledge. Moolelo (traditional stories) e.g., Kuapākaa (Nakuina, 1905), translated as The Wind Gourd of Laamaomao, tells of Kuapākaa controlling all the winds of Hawai';i by chanting their names--a metaphor for the power of knowledge of winds, rains and their patterns. In the moolelo of Kalapana, a boy hero challenges and defeats the king of Kauai to a life-and-death riddling contest (Nakuina, 1902). Maly's (2001) translation of a riddle involving 22 zones spanning mountaintop to deep-sea underscores the knowledge base informing sustainable practices. Articles provide insight into indigenous maps (Nogelmeier, personal communication) while riddling contests (Beckwith, 1940/1970) establish demonstrations of knowledge as central to power, identity, and status. Eight field-based lessons have been presented to formal and informal science educators, with teachers adapting lessons for 3rd-12th grade students. Graduate students Spencer, Stone

  7. Medical advertising: the Family Encyclopaedia of Medicine scandal of 1914.

    Science.gov (United States)

    Jellinek, E H

    2008-12-01

    The past 100 years have seen a transition from a total ban in Britain on all advertising by doctors to the laity to almost total freedom of medical information, with probable benefit to public health but also a risk of loss of privacy. The Family Encyclopaedia of Medicine, written by Dr Hugh Howard Riddle and published by Lord Northcliffe's Daily Mail in 1914, started a flood of medical journalism in the press and the newer media. The lavishly advertised misattribution of its authorship to 'thirty eminent specialists', including Clifford Allbutt and William Osler, caused a major rumpus in the London Royal College of Physicians, but the fortnightly publication continued and became a four-volume book, popular with a public avid for more and more medical information.

  8. The ‘Gestapu’ events of 1965 in Indonesia: New evidence from Russian and German archives

    Directory of Open Access Journals (Sweden)

    Ragna Boden

    2008-12-01

    Full Text Available One of the unsolved riddles of Indonesian history in the twentieth century is the so-called Gestapu affair and its aftermath. For the murder of six army generals on the night of 30 September 1965 the Indonesian communists and President Soekarno were widely held responsible. Indonesian leftists – real and alleged – were persecuted; hundreds of thousands were killed. The longterm consequences affected Indonesian domestic as well as foreign policy: the changeover in government resulted in 30 years of rule by Soeharto; the Partai Komunis Indonesia (PKI, Indonesian Communist Party and leftist organizations were banned; relations with China were severed, those with the Union of Soviet Socialist Republics (USSR were reduced; and ties with Washington and the Western world intensified.

  9. Looking for Clues to the Mystery of Life on Earth

    Science.gov (United States)

    Balter, Michael

    1996-08-01

    From the vast central hall in Chambord Castle, the largest of the great chateaux on France's River Loire, an ornate double-helical staircase rises to a roof terrace. It was an appropriate setting for a banquet of the International Society for the Study of the Origin of Life (ISSOL), which held its triennial meeting last month in nearby Orleans. Without double-helical DNA and RNA molecules, life would not exist. At the meeting, nearly 300 scientists, including three Nobel laureates, grappled with the riddle of how these molecules first appeared and how they evolved into self-reproducing cells-questions that have gained new urgency with the hint that life in some form also may have evolved on Mars (see pages 864 and 924).

  10. Developing a strategy for improving efficiency in the heating sector in central and eastern Europe

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, A.S. [World Bank, Washington, DC (United States)

    1995-12-31

    Heating is a vital energy service in Central and Eastern Europe, but the current delivery mechanisms are riddled with problems. District heating (DH) in its present technical form and with the present management structures is an inefficient system which produces expensive heat. Customers cannot control it and react to overheating by opening windows, even in winter. DH facilities together with other forms of individual heating are responsible for air pollution, causing severe impacts on the health of urban residents. The issues relating to DH are discussed, the first World Bank activities and experiences with projects in Poland are analyzed, and the cornerstones of a strategy to support future World Bank financing and the development of sound heating policies in CEE are presented.

  11. Application of the one-dimensional Fourier transform for tracking moving objects in noisy environments

    Science.gov (United States)

    Rajala, S. A.; Riddle, A. N.; Snyder, W. E.

    1983-01-01

    In Riddle and Rajala (1981), an algorithm was presented which operates on an image sequence to identify all sets of pixels having the same velocity. The algorithm operates by performing a transformation in which all pixels with the same two-dimensional velocity map to a peak in a transform space. The transform can be decomposed into applications of the one-dimensional Fourier transform and therefore can gain from the computational advantages of the FFT. The aim of this paper is the concern with the fundamental limitations of that algorithm, particularly as relates to its sensitivity to image-disturbing parameters as noise, jitter, and clutter. A modification to the algorithm is then proposed which increases its robustness in the presence of these disturbances.

  12. PRESERVING THE TRADITIONS OF EASTER EGGS IN THE EDUCATION OF CHILDREN OF THE HIGHLANDS

    Directory of Open Access Journals (Sweden)

    Oksana Poyasyk

    2015-04-01

    Full Text Available Nowadays the problem of spiritual revival of society is acute. Welfare in general depends on the spirituality of each of us. Spiritual and cultural level determines the strength of the nation. One of the most important tasks of spiritual education is to cultivate the sense of belonging to the people, traditions, art and history. It begins not only with mother's lullaby, parental word, granny’s tales, folk songs, proverbs, riddles, but with the subjects of folk art, which provide wisdom of ancestors and human values. Folk art provides an excellent basis for the development of culture. It all passes, generations are dying, everything is turned into ashes; only the spirit of the nation remains embodied in the works of folk art.

  13. Requirements and standards for organelle genome databases

    Energy Technology Data Exchange (ETDEWEB)

    Boore, Jeffrey L.

    2006-01-09

    Mitochondria and plastids (collectively called organelles)descended from prokaryotes that adopted an intracellular, endosymbioticlifestyle within early eukaryotes. Comparisons of their remnant genomesaddress a wide variety of biological questions, especially when includingthe genomes of their prokaryotic relatives and the many genes transferredto the eukaryotic nucleus during the transitions from endosymbiont toorganelle. The pace of producing complete organellar genome sequences nowmakes it unfeasible to do broad comparisons using the primary literatureand, even if it were feasible, it is now becoming uncommon for journalsto accept detailed descriptions of genome-level features. Unfortunatelyno database is currently useful for this task, since they have littlestandardization and are riddled with error. Here I outline what iscurrently wrong and what must be done to make this data useful to thescientific community.

  14. Insight into economies of scale for waste packaging sorting plants

    DEFF Research Database (Denmark)

    Cimpan, Ciprian; Wenzel, Henrik; Maul, Anja

    2015-01-01

    of economies of scale and discussed complementary relations occurring between capacity size, technology level and operational practice. Processing costs (capital and operational expenditure) per unit waste input were found to decrease from above 100 € for small plants with a basic technology level to 60......This contribution presents the results of a techno-economic analysis performed for German Materials Recovery Facilities (MRFs) which sort commingled lightweight packaging waste (consisting of plastics, metals, beverage cartons and other composite packaging). The study addressed the importance......-70 € for large plants employing advanced process flows. Typical operational practice, often riddled with inadequate process parameters was compared with planned or designed operation. The former was found to significantly influence plant efficiency and therefore possible revenue streams from the sale of output...

  15. The riddle of style changes in the visual arts after interference with the right brain

    Directory of Open Access Journals (Sweden)

    Olaf eBlanke

    2012-01-01

    Full Text Available What is visual art? What are paintings? What are films? Although innumerous answers have been proposed to these questions, we here analyze the paintings and films of several visual artists, who suffered from a well-defined neuropsychological deficit, visuo-spatial hemineglect, following vascular stroke to the right brain. We focus our analysis in particular on the oeuvre of Lovis Corinth and Luchino Visconti and point out aspects of their post-stroke paintings and films (that differ from their pre-stroke work and argue that these changes may be associated with visuo-spatial hemineglect. We discuss how the neuropsychological investigation of visual artists may allow us to investigate the relationship between brain and art.

  16. The 'spontaneous' acoustic emission of the shock front in a perfect fluid: solving a riddle

    International Nuclear Information System (INIS)

    Brun, Louis

    2013-06-01

    In the fifties, S. D'yakov discovered that theory allows for suitable EOS shock fronts to emit acoustic waves 'spontaneously'. Section 90 of Fluid Mechanics of Landau and Lifshitz, 2. Ed., deals with the phenomenon, leaving it unexplained. This open question was chosen to introduce a monograph in progress about 'the shock front in the perfect fluid'. The novelty of our approach consists in having the phenomenon generated - which means it is non-spontaneous -- from an appropriate solicitation of the front and studying its development analytically. The non classical source and mechanism of the emission are thus brought to light. (author)

  17. The riddle of style changes in the visual arts after interference with the right brain.

    Science.gov (United States)

    Blanke, Olaf; Pasqualini, Isabella

    2011-01-01

    We here analyze the paintings and films of several visual artists, who suffered from a well-defined neuropsychological deficit, visuo-spatial hemineglect, following vascular stroke to the right brain. In our analysis we focus in particular on the oeuvre of Lovis Corinth and Luchino Visconti as both major artists continued to be highly productive over many years after their right brain damage. We analyzed their post-stroke paintings and films, indicate several aspects that differ from their pre-stroke work (omissions, use of color, perseveration, deformation), and propose-although both artists come from different times, countries, genres, and styles-that their post-stroke oeuvre reveals important similarities in style. We argue that these changes may be associated with visuo-spatial hemineglect and the right brain. We discuss future avenues of how the neuropsychological investigation of visual artists with and without neglect may allow us to investigate the relationship between brain and art.

  18. Induced metamorphosis in crustacean y-larvae: towards a solution to a 100-year-old riddle

    DEFF Research Database (Denmark)

    Glenner, Henrik; Høeg, Jens T; Grygier, Mark J

    2008-01-01

    at our study site alone) indicates that the adult organism may play a significant ecological role. However, despite intense efforts, the adult y-organism has never been identified, and nothing is therefore known about its biology. RESULTS: We have successfully and repeatedly induced metamorphosis of y...

  19. Quantitative characterization of initiation and propagation in stress corrosion cracking. An approach of a phenomenological model

    International Nuclear Information System (INIS)

    Raquet, O.

    1994-01-01

    A purely phenomenological study of stress corrosion cracking was performed using the couple Z2CN 18.10 (304L) austenitic stainless steel/boiling MgCl 2 aqueous solution. The exploitation of the morphological information (shape of the cracks and size distribution) available after constant elongation rate tests led to the proposal of an analytical expression of the crack initiation and growth rates. This representation allowed to quantitatively characterize the influence of the applied strain rate as well as the effect of corrosion inhibitors on the crack initiation and propagation phases. It can be used in the search for the stress corrosion cracking mechanisms as a 'riddle' for the determination of the rate controlling steps. As a matter of fact, no mechanistic hypothesis has been used for its development. (author)

  20. Quantitative characterization of initiation and propagation in stress corrosion cracking. An approach of a phenomenological model; Caracterisation quantitative de l`amorcage et de la propagation en corrosion sous contrainte. Approche d`une modelisation phenomenologique

    Energy Technology Data Exchange (ETDEWEB)

    Raquet, O

    1994-11-25

    A purely phenomenological study of stress corrosion cracking was performed using the couple Z2CN 18.10 (304L) austenitic stainless steel/boiling MgCl{sub 2} aqueous solution. The exploitation of the morphological information (shape of the cracks and size distribution) available after constant elongation rate tests led to the proposal of an analytical expression of the crack initiation and growth rates. This representation allowed to quantitatively characterize the influence of the applied strain rate as well as the effect of corrosion inhibitors on the crack initiation and propagation phases. It can be used in the search for the stress corrosion cracking mechanisms as a `riddle` for the determination of the rate controlling steps. As a matter of fact, no mechanistic hypothesis has been used for its development. (author).

  1. Where was ENSO strongest?

    Science.gov (United States)

    Cane, M. A.; Chen, D.; Kaplan, A.

    2008-12-01

    Mark A. Cane, Dake Chen, Alexey Kaplan The description of this session begins: "Historical SST records suggest that for the past three decades, ENSO has been anomalously strong" and goes on to ask why. In this talk we dispute this interpretation of the historical record from within the historical record. In particular, we suggest that the most "anomalously strong" period in the historical ENSO record is the late nineteenth century. This claim requires a discussion of how we measure "ENSO strength". We also speculate on possible reasons for the strength of ENSO in this earlier period. Finally, we consult the models, and in reiteration of the collective conclusion of all speakers at this session, find that the riddles the models provide are inelegant and disobliging, lacking the cryptic wisdom of the classical oracles.

  2. Ontology, Criticism, and the Riddle of Art Versus Non-Art in The Transfiguration of the Commonplace

    Directory of Open Access Journals (Sweden)

    Arthur C. Danto

    2008-01-01

    Full Text Available In this "Reply to my Critics," I explain that The Transfiguration of the Commonplace was essentially a contribution to the ontology of art in which two necessary conditions emerge as essential to a real definition of the art work: that an artwork must (a have meaning and (b must embody its meaning. Many issues have emerged in the course of art's history that are very much part of its practice but are not part of art's essence. In response to Cynthia Freeland, I argue that though the book does not address art criticism, the two necessary conditions specify a viable rule for critical practice, as was recognized by Hegel. And in response to Ivan Gaskell, I argue that the definition of art arrived at in the book is capable of drawing a distinction between art works and artifacts.

  3. Can aging be programmed?

    DEFF Research Database (Denmark)

    Kowald, Axel; Kirkwood, Thomas B. L.

    2016-01-01

    The evolution of the aging process has long been a biological riddle, because it is difficult to explain the evolution of a trait that has apparently no benefit to the individual. Over 60 years ago, Medawar realized that the force of natural selection declines with chronological age because...... of unavoidable environmental risks. This forms the basis of the mainstream view that aging arises as a consequence of a declining selection pressure to maintain the physiological functioning of living beings forever. Over recent years, however, a number of articles have appeared that nevertheless propose...... the existence of specific aging genes; that is, that the aging process is genetically programmed. If this view were correct, it would have serious implications for experiments to understand and postpone aging. Therefore, we studied in detail various specific proposals why aging should be programmed. We find...

  4. Decision making with epistemic uncertainty under safety constraints: An application to seismic design

    Science.gov (United States)

    Veneziano, D.; Agarwal, A.; Karaca, E.

    2009-01-01

    The problem of accounting for epistemic uncertainty in risk management decisions is conceptually straightforward, but is riddled with practical difficulties. Simple approximations are often used whereby future variations in epistemic uncertainty are ignored or worst-case scenarios are postulated. These strategies tend to produce sub-optimal decisions. We develop a general framework based on Bayesian decision theory and exemplify it for the case of seismic design of buildings. When temporal fluctuations of the epistemic uncertainties and regulatory safety constraints are included, the optimal level of seismic protection exceeds the normative level at the time of construction. Optimal Bayesian decisions do not depend on the aleatory or epistemic nature of the uncertainties, but only on the total (epistemic plus aleatory) uncertainty and how that total uncertainty varies randomly during the lifetime of the project. ?? 2009 Elsevier Ltd. All rights reserved.

  5. Data anxieties: Finding trust in everyday digital mess

    Directory of Open Access Journals (Sweden)

    Sarah Pink

    2018-01-01

    Full Text Available Digital data is an increasing and continual presence across the sites, activities and relationships of everyday life. In this article we explore what data presence means for the ways that the everyday is organised, sensed, and anticipated. While digital data studies have demonstrated how data is deeply entangled with the way in which everyday life is lived out and valued, at the same time our relationships with data are riddled with anxieties or small niggles or tricky trade-offs and their use is often chaotic and muddled, part of the inevitable uncertainty about what will happen next. If the presence of data is part of the environments we inhabit, this raises the question of how and why data is valuable to us and what forms of hope and trust enable this value to further develop.

  6. THE PLACE OF GRAPE IN TURKISH FOLK CULTURE AND IN CONTEXT OF MYTHOLOGY / TÜRK HALK KÜLTÜRÜNDE VE MITOLOJIK BAĞLAMDA ÜZÜMÜN YERI

    Directory of Open Access Journals (Sweden)

    Dr. Ebru ŞENOCAK

    2008-10-01

    Full Text Available The grape grown since the pre-historic eras has adistinct part within the verbal cultural tradition as wellas being an important health source meeting thenutrition need in Turkish folk culture. The grape thatwas the theme of folk songs, riddles, proverbs, idioms,tales and legends in folk literature was also used with itsboth curing and symbolic meanings in having a child,marriage and wedding customs, drinking wine, dowrytradition, folk beliefs and folk medicine in our folklore. In the researches carried out depending on the factthat the grape, raw material of the wine, is accepted asthe drink of the Gods in mythology and it is mentioned inTorah, Bible and the Psalms of David as the sacred drink,it was determined that in Turkish culture and mythology,the grape is the symbol of beauty, fertility, blood, soul,love and health.

  7. Radicalizing Conservatismen

    DEFF Research Database (Denmark)

    Skov, Christian Egander

    2012-01-01

    This paper deals with the difficulties of not only defining conservatism, but also finding a viable analytical approach to conservatism informed by such definition. In doing so I shall point towards one way approaching the subject, focusing on the decontestation of the concept of nomos. Secondly...... the paper deals with one specific instance of conservatives struggling over the ideological substance of conservatism. The question of the nature of conservatism has continued to riddle the analysts of ideology in general and of conservatism in particular. This can be seen not only in literature...... on conservatism, but also in conservative literature. The need to establish the articles of faith of true conservatism and delimit this creed from conservative heresies is a recurring theme, and conservatives seem engaged in never ending conceptual civil wars. Certainly this isn’t a feature unique to conservatism...

  8. Językowo-kulturowy obraz ręki w polszczyźnie ludowej

    Directory of Open Access Journals (Sweden)

    Agnieszka Litwińczuk

    2013-06-01

    Full Text Available The linguocultural image of hand in Polish folk language The goal of this paper is a reconstruction of the linguocultural image of ręka (hand in the Polish folk language, as defined by a cognitive model proposed by Bartmiński in the 1980’s. Among the sources considered here are the linguistic system itself (as exemplified by dictionaries of the Polish language, etymological dictionaries, dialect dictionaries as well as literary texts, including folk songs and prose (e.g. riddles, sayings, fairy tales, and folk traditions and beliefs, recorded in the FOLBAS computer base and in the UMCS Ethnolinguistic Archives. From all these sources there emerges a rich and complex image showing this part of the body mainly from a functional perspective and appreciation of its role in Polish folk culture.

  9. Pengaruh Pemberian Valsartan Dan Kurkumin Terhadap Pembentukan Fibrosis Di Tubulus Proksimal Ginjal Akibat Obstruksi Ureter Unilateral pada Tikus Wistar.

    Directory of Open Access Journals (Sweden)

    Lubis M

    2013-01-01

    Full Text Available AbstrakPendahuluan: Obstruksi ureter adalah kondisi terhalangnya aliran urin dari ginjal ke buli-buli, adanya obstruksi pada ureter memperlambat laju filtrasi glomerulus dan dapat menyebabkan kerusakan parenkim ginjal. Fibrosis pada ginjal yang obstruksi timbul melalui dua mediator yaitu tumor nekrotik factor (TNF-α dan angiotensin II. Penghambatan kedua mediator ini akan menurunkan tingkat fibrosis di tubulus proksimal ginjal akibat obstruksi. Zat yang bisa menghambat TNF-α salah satunya adalah kurkumin sedangkan Angitensin II dapat dihambat dengan valsatran. Metode: Penelitian ini merupakan penelitian eksperimental, tikus wistar dibagi dalam dua kelompok dengan jumlah tiap kelompok adalah 15 ekor. Proksimal ureter kanan diikat dan kelompok perlakuan 1 sebagai kontrol diberi valsatran, kelompok perlakuan2 diberi valsartan dan kurkumin. Pemberian oral, dimana obat dilakukan pengenceran. Hari ke lima belas dilakukan pengambilan ginjal tikus wistar, diperiksa histologi. Pembentukan fibrosis di tubulus proksimal dianalisa dengan uji statistik chisquare dengan koreksi Yates dan t test, sedang terbentuknya degenerasi hidrofik dan terbentuknya atrofi pada tubulus proksimal dianalisa dengan uji statistik t test. Hasil: Adanya perbedaan bermakna perubahan pembentukan fibrosis di tubulus proksimal ginjal antara kelompok perlakuan dan kontrol ( Chi Squqre didapat nilai p ≤ 0,001 dan dengan t test didapat nilai p ≤ 0,000. Terbentuknya degenerasi hidrofilik di tubulus proksimal ginjal terdapat perbedaan bermakna terbentuknya degenerasi hidrofilik kelompok perlakuan dan kelompok kontrol ( t test didapatkan nilai p ≤ 0,000. Terbentuknya atrofi di tubulus proksimal terdapatt perbedaan bermakna terbentuknya atrofi di tubulus proksimal ginjal kelompok perlakuan dan kelompok kontrol ( t test didapat nilai p ≤ 0,000. Kesimpulan: Ada perbedaan pengaruh pemberian valsartan dan valsartan + kurkumin terhadap pembentukan fibrosis di tubulus proksimal ginjal

  10. TRASTORNO LÍMITE DE PERSONALIDAD: Tratamiento desde un enfoque Cognitivo Conductual

    Directory of Open Access Journals (Sweden)

    Tamara E. Torres G.

    2007-01-01

    Full Text Available El Trastorno Límite de Personalidad (TLP ha sido u n desafió constante para los profesionales por la variabilidad sintomática que presenta, lo qu e conlleva dificultades en su diagnóstico y tratamiento. Además, ha aumentado su prevalencia en el último tiempo por lo que la importancia de trabajar este trastorno tanto a nivel de diagnós tico como psicoterapéutico debe ser acogido por profesionales de vasta experiencia y por los que es tán en el transcurso de su formación para poder lograr un mejor ejercicio profesional y ético con e stos pacientes, sin caer en diagnósticos y tratamientos erróneos como ocurrió en épocas anter iores. El enfoque Cognitivo Conductual ha demostrado grand es avances, tanto en la identificación como en la mejoría de estos pacientes, integrando u na Reestructuración Cognitiva, postulada por Aaron Beck, como tomando los aportes de la Terapia Comportamental Dialéctica propuesta por Marsha Linehan. En este escrito se mencionarán los criterios diagnó sticos y el aporte en el tratamiento del TLP en base a los dos autores anteriormente mencionados.

  11. French-Canadian translation and validation of four questionnaires assessing hearing impairment and handicap.

    Science.gov (United States)

    Vincent, Claude; Gagné, Jean-Pierre; Leroux, Tony; Clothier, Audrey; Larivière, Marianne; Dumont, Frédéric S; Gendron, Martine

    2017-04-01

    Questionnaires evaluating hearing impairment are available in English but there is a need for French standardised questionnaires for researchers as well as for audiologists and other clinicians. The objective of this study is to describe the translation and validation of four questionnaires that assess different aspects of hearing impairment and handicap among elders with hearing loss, by comparing the main score and psychometric evaluation of original and French-Canadian (FC) versions of the World Health Organization Disability Assessment Scale II (WHO-DAS II), the Screening Test for Hearing Problems (STHP), the Abbreviated Profile of Hearing Aid Benefit (APHAB) and the Measure of Audiologic Rehabilitation Self-Efficacy for Hearing Aids (MARS-HA). Vallerand method: translation and back-translation by two translators, revision by a committee of experts and pre-tested with five bilingual older participants. Participants (n = 29) were 65 years of age or older including 21 with hearing aids. The psychometric properties (internal consistency, temporal stability after four weeks) indicate good reliability for most of the translated questionnaires and their subscales, especially the WHO-DAS II. The translations in FC of two hearing loss and two hearing aid questionnaires were validated. It is recommended to pursue the demonstration for temporal stability for the STHP.

  12. A Vindication of the Spanish Mother. Maternal Images in the Filmic Make-over of the Nation

    Directory of Open Access Journals (Sweden)

    Andrés Zamora

    2009-06-01

    Full Text Available The maternal figure as an explicit or oblique image of the Spanish nation has undergone a good share of indignities throughout the modern cultural history of the country, from the nineteenth-century Mater Dolorosa to the stepmother of those forced into exile after the civil war, from the terrible matriarchs of Benito Peréz Galdós, Federico Garcia Lorca and Camilo José Cela to the patriarchal mothers of Spanish oppositional cinema in the final phase of the dictatorship and first years of the democratic transition. This latter avatar of the Spanish mother, so well reconstructed by Marsha Kinder, had the bewildering destiny of being both the displaced incarnation of authoritarian power and the object of the rebellion and the violent ire of her offspring. After the demise of the Franco regime, one of the most urgent tasks of the new democratic period was to produce a redefinition of the Spanish national identity, sequestered and monopolized for so many years by the ideological patchwork of the dictatorship. Towards that end, contemporary Spanish cinema has undertaken an extraordinary revision and vindication of the mother against the dire history of her evil or martyred antecedents, as a fundamental, though subtle, gesture in the attempt to rebuild, suture, and make over the nation.

  13. The Concept of Cosmic Tree in Armenian and Iranian Cosmologies

    Science.gov (United States)

    Farmanyan, S. V.; Mickaelian, A. M.

    2016-09-01

    Cosmic Tree or Tree of Life is a common motif in various world theologies, mythologies, and philosophies. In the present study we focus on Armenian and Iranian Cosmic Tree. In ancient Armenia, the Tree of Life (Կենաց Ծառ) is a religious symbol and is drawn on walls of fortresses and carved on the armour of warriors. According to ancient Armenians the center of the Universe is located at the crown of the tree or the column, which is the closest to the sky. We explore the idea of cosmic tree in the riddles, prayers, medieval rituals and miniatures. In the riddles, the tree mostly symbolizes the celestial phenomena (Sun, Stars, and Heavens), different units of time (years, months, weeks, days, and seasons), the people, Jerusalem, the apostles and Jesus Christ. The branches of the tree were equally divided on the right and left sides of the stem, with each branch having one leaf, and one leaf on the apex of the tree. Servants stood on each side of the tree with one of their hands up as if they are taking care of the tree. In pre-Islamic Persian mythology, the Gaokerena world tree is a large, sacred Haoma tree which bears all seeds. Ahriman created a frog to invade the tree and destroy it, aiming at preventing all trees from growing on the Earth. As a reaction, God (Ahura Mazda) created two kar fish staring at the frog to guard the tree. The concept of world tree in Persian Mythology is very closely related to the concept of the Tree of Life. Another related issue in ancient mythology of Iran is the myth of Mashya and Mashyane, two trees who were the ancestors of all living beings. This myth can be considered as a prototype for the creation myth where living beings are created by Gods (who have human forms). We come to the conclusion that in both cultures, no matter of the present different religions, the perception of Cosmic Tree is interconnected to the life on our planet and served as a metaphor for common descent in the evolutionary sense.

  14. Investigating Near Space Interaction Regions: Developing a Remote Observatory

    Science.gov (United States)

    Gallant, M.; Mierkiewicz, E. J.; Oliversen, R. J.; Jaehnig, K.; Percival, J.; Harlander, J.; Englert, C. R.; Kallio, R.; Roesler, F. L.; Nossal, S. M.; Gardner, D.; Rosborough, S.

    2016-12-01

    The Investigating Near Space Interaction Regions (INSpIRe) effort will (1) establish an adaptable research station capable of contributing to terrestrial and planetary aeronomy; (2) integrate two state-of-the-art second generation Fabry-Perot (FP) and Spatial Heteorodyne Spectrometers (SHS) into a remotely operable configuration; (3) deploy this instrumentation to a clear-air site, establishing a stable, well-calibrated observatory; (4) embark on a series of observations designed to contribute to three major areas of geocoronal research: geocoronal physics, structure/coupling, and variability. This poster describes the development of the INSpIRe remote observatory. Based at Embry-Riddle Aeronautical University (ERAU), initiative INSpIRe provides a platform to encourage the next generation of researchers to apply knowledge gained in the classroom to real-world science and engineering. Students at ERAU contribute to the INSpIRe effort's hardware and software needs. Mechanical/optical systems are in design to bring light to any of four instruments. Control software is in development to allow remote users to control everything from dome and optical system operations to calibration and data collection. In April 2016, we also installed and tested our first science instrument in the INSpIRe trailer, the Redline DASH Demonstration Instrument (REDDI). REDDI uses Doppler Asymmetric Spatial Heterodyne (DASH) spectroscopy, and its deployment as part of INSpIRe is a collaborative research effort between the Naval Research Lab, St Cloud State University, and ERAU. Similar to a stepped Michelson device, REDDI measures oxygen (630.0 nm) winds from the thermosphere. REDDI is currently mounted in a temporary location under INSpIRe's main siderostat until its entrance optical system can be modified. First light tests produced good signal-to-noise fringes in ten minute integrations, indicating that we will soon be able to measure thermospheric winds from our Daytona Beach testing site

  15. The Problem with Metzinger

    Directory of Open Access Journals (Sweden)

    Graham Harman

    2011-06-01

    Full Text Available This article provides a critical treatment of the ontology underlying Thomas Metzinger’s Being No One. Metzinger asserts that interdisciplinary empirical work must replace ‘armchair’ a priori intuitions into the nature of reality; nonetheless, his own position is riddled with unquestioned a priori assumptions. His central claim that ‘no one has or has ever had a self’ is meant to have an ominous and futuristic ring, but merely repeats a familiar philosophical approach to individuals, which are undermined by reducing them downward to their material underpinnings, and ‘overmined’ by reducing them upward to their functional effects. Ultimately, Metzinger blends a rigid form of traditional materialism with an ontology of processes and events that is too reminiscent of late 1990’s continental philosophy. In both directions, the novelty and fertility of Metzinger’s position can be called into question.

  16. Novel electrical transport properties in conducting polymers such as polythiophene and Poly(3-Methylthiophene)

    International Nuclear Information System (INIS)

    Kazama, Shigeo; Masubuchi, Shin-ichi; Matsuyama, Tomochika; Matsushita, Rokuji.

    1994-01-01

    Electric transport properties in most of the conducting organic polymers have provided a riddle that prevents a thorough physical understanding of the conduction mechanism. Major difficulties for approaching the most substantial aspect in the electrical transport properties underlie in complicated higher order structure inherent to polymeric materials consisting of crystalline regions entangled with disordered amorphous regions. In order to clearly understand the origin of the metallic nature of conducting polymers, we have to extract the proper transport properties characteristics of the ordered crystalline regions. We have made a series of experimental studies of the transport properties in conductive polythiophene and poly(3-methylthiophene) obtained with the electrochemical polymerization. For polythiophene, we have investigated both the as-grown samples and the ones that contain controlled amount of dopant species exchanged after the neutralization aiming to see the effect of dopant concentration on the transport properties. (author)

  17. Gravity how the weakest force in the universe shaped our lives

    CERN Document Server

    Clegg, Brian

    2012-01-01

    Gravity is one of the most accepted laws of science. Drop an object and it falls to earth because of the attraction between the earth and the object. What alerts the earth and the object to act? Is there a sort of communication between them? Theoretical physicists have struggled to explain gravitational attraction over distance since Einstein posed his theories of special and general relativity. Quantum theory, string theory, M theory, and other theoretical inquiries have failed to solve the riddle. In his history of gravity from the Big Bang to the present, popular science author Clegg recounts international efforts to understand what is thought to be the weakest yet most essential force holding the universe together. Black holes, warps in space and time, and antimatter are featured in this wide-ranging account, which will be of interest to science students and readers of science fiction.

  18. Formation, evolution, and dynamics of young solar systems

    CERN Document Server

    Gressel, Oliver

    2017-01-01

    This book's interdisciplinary scope aims at bridging various communities: 1) cosmochemists, who study meteoritic samples from our own solar system, 2) (sub-) millimetre astronomers, who measure the distribution of dust and gas of star-forming regions and planet-forming discs, 3) disc modellers, who describe the complex photo-chemical structure of parametric discs to fit these to observation, 4) computational astrophysicists, who attempt to decipher the dynamical structure of magnetised gaseous discs, and the effects the resulting internal structure has on the aerodynamic re-distribution of embedded solids, 5) theoreticians in planet formation theory, who aim to piece it all together eventually arriving at a coherent holistic picture of the architectures of planetary systems discovered by 6) the exoplanet observers, who provide us with unprecedented samples of exoplanet worlds. Combining these diverse fields the book sheds light onto the riddles that research on planet formation is currently confronted with, a...

  19. Unpredictable Property of a Kicked Billiard Ball

    International Nuclear Information System (INIS)

    Shen Ying; Dai Jun; Jiang Yumei; He Yue; He Daren

    2006-01-01

    A simultaneous change in the systemic property of a kicked billiard ball is observed from an entirely smooth and conservative state to a piecewise smooth and quasi-dissipative state when a single controlling parameter has been adjusted. The transition induces a sudden change of a typical conservative stochastic web into a transient web. The iterations on the transient web eventually escape to some elliptic islands. In the meantime, a fat fractal forbidden web, which appears also at the threshold, grows up and cuts away increasingly more parts from the original conservative stochastic web. We numerically show that the initial conditions that generated different attractors are mixed in a random manner and the pattern remains unchanged even when smaller and smaller scales are used for examination, indicating a riddle-like basin structure that practically rules out the possibility of predicting the attractors from a given initial condition

  20. The epistemological and historical concept of nostoc from an indiciary lecture of George Canguilhem's "The cell theory"

    Directory of Open Access Journals (Sweden)

    Maurício de Carvalho Ramos

    2016-05-01

    Full Text Available Through an indiciary lecture of Canguilhem's article  "The cell theory", I propose, methodically guided by a epistemological-historical style research, the construction of the concept of nostoc as a metamorphic concept that integrated the concepts of primordial blastema and biblical slime of the French botanist Charles Naudin, set up a scientific culture of broad reach committed to solving the riddle of the morphological unity of organic and vital beings. The concept of Nostoc refers alchemically a gelatinous substance from the stars and endowed with balsamic medical virtues and botanically, a cianoficea algae of Nostoc genus. Examined the ideas of Canguilhem, Naudin, Jung and Paracelsus, this concept is proposed as a nucleoplasmatic oscillation, understood as a specific form of expression of the mythical-scientific theme of tension between continuity and discontinuity, as shown by Canguilhem in his history of cell concept.

  1. Food Taxes: A New Holy Grail?

    Directory of Open Access Journals (Sweden)

    Ignaas Devisch

    2013-01-01

    Full Text Available In an effort to reduce the growing prevalence of overweight and obesity, food taxes have been introduced in several European countries, the so-called ‘obesitax’. As yet little evidence is at hand, policy measures are being taken to counterweight the consumption of unhealthy food or the increasing diet-related diseases. Several questions need to be discussed, starting from a general perspective: can food taxes become an appropriate and just policy measure to reduce overweight and obesity and therefore increase consumer’s health? The implementation of an effective and fair food tax is an exercise riddled with uncertainty. Not only is there a need for evidence on the health and economic impact of food taxes, we also have to think about a conceptual and ethical discussion concerning the balance between health imperatives and public health on the one hand, and social and ethical standards on the other hand.

  2. Mental Suffering as a Struggle with Words

    DEFF Research Database (Denmark)

    Rosfort, René

    2016-01-01

    of suffering. I unfold this argument in five steps. I will first look at the vexed question of what emotions are. Discussing biological and rational conceptions of emotions, I argue that human emotions are deeply ambiguous phenomena constituted by an opaque combination of biological factors and rational......Human emotional life is structured and to a certain extent constituted by language, and yet making sense of and communicating how we feel is often a challenge. In this article, I will argue that a person’s struggle to make sense of and articulate her suffering plays a major role in the experience...... factors. In the second section, I will argue that instead of trying to solve the ontological riddle of emotions we should investigate the actual experience of emotions. I examine the dialectics of the conceptual and the phenomenal aspects of our emotional experience, arguing that we need to adopt...

  3. The Reasons for Living Scale-Military Version: Assessing Protective Factors Against Suicide in a Military Sample.

    Science.gov (United States)

    Deutsch, Anne-Marie; Lande, R Gregory

    2017-07-01

    Military suicide rates have been rising over the past decade and continue to challenge military treatment facilities. Assessing suicide risk and improving treatments are a large part of the mission for clinicians who work with uniformed service members. This study attempts to expand the toolkit of military suicide prevention by focusing on protective factors over risk factors. In 1983, Marsha Linehan published a checklist called the Reasons for Living Scale, which asked subjects to check the reasons they choose to continue living, rather than choosing suicide. The authors of this article hypothesized that military service members may have different or additional reasons to live which may relate to their military service. They created a new version of Linehan's inventory by adding protective factors related to military life. The purpose of these additions was to make the inventory more acceptable and relevant to the military population, as well as to identify whether these items constitute a separate subscale as distinguished from previously identified factors. A commonly used assessment tool, the Reasons for Living Inventory (RFL) designed by Marsha Linehan, was expanded to offer items geared to the military population. The RFL presents users with a list of items which may be reasons to not commit suicide (e.g., "I have a responsibility and commitment to my family"). The authors used focus groups of staff and patients in a military psychiatric partial hospitalization program to identify military-centric reasons to live. This process yielded 20 distinct items which were added to Linehan's original list of 48. This expanded list became the Reasons for Living-Military Version. A sample of 200 patients in the military partial hospitalization program completed the inventory at time of or close to admission. This study was approved by the Institutional Review Board at Walter Reed National Military Center for adhering to ethical principles related to pursuing research

  4. Gender cognitive: differences are in the aspect of neurobiology, genetics, cogitative patternes and social behavior

    Directory of Open Access Journals (Sweden)

    O. V. Chuikova

    2016-03-01

    Frontal stakes are functionally different for men and for women. Probably also, that left and right frontal stakes functionally are very different for men and in less degree for women. Thus extremely improbably, that these functional differences are limited to distinction between a language and unverbal processes. Masculine and woman strategies of making decision are different, and the lateralization of functions of frontal stakes is also different for them. Masculine and woman strategies of making decision are different, and the lateralization of functions of frontal stakes is also different for them. It was known a long ago, that structural, biochemical and functional distinctions between hemispheres are stronger expressed for men, what for women. Therefore must not surprise, what functional distinctions more than between two woman frontal stakes between two masculine frontal stakes. The riddle of cognitive distinctions between genders can appear one of such problems, that needs to be carried from an empiric sphere in the sphere of the developed theoretical disciplines.

  5. Computer Security: oops, there it goes...

    CERN Multimedia

    Stefan Lueders, Computer Security Team

    2015-01-01

    Do you love riddles, hide and seek or picture puzzles a la “Where’s Wally”? Then take a look at the photo below, and try to spot the error.   It is hard to spot: the yellow sticker on the computer screen shows a password providing access to the web application running on the screen. Surprising! Fortunately, this sticker was quickly removed by the corresponding system owners and the password changed. However, we can all make improvements: passwords must never be written down and definitely not on stickers attached to screens, keyboards, or desks. Remember: your password is your “toothbrush” - a toothbrush you do not share and you change regularly. Neither your colleagues, your supervisor, the Service Desk or the Computer Security Team have any valid reason to ask for it. They should not and will never do so. The same is valid for any external company: UBS, Paypal, Amazon, Facebook or Google will never ask you for your pass...

  6. Momentum-resolved hidden-order gap reveals symmetry breaking and origin of entropy loss in URu2Si2

    Science.gov (United States)

    Bareille, C.; Boariu, F. L.; Schwab, H.; Lejay, P.; Reinert, F.; Santander-Syro, A. F.

    2014-07-01

    Spontaneous symmetry breaking in physical systems leads to salient phenomena at all scales, from the Higgs mechanism and the emergence of the mass of the elementary particles, to superconductivity and magnetism in solids. The hidden-order state arising below 17.5 K in URu2Si2 is a puzzling example of one of such phase transitions: its associated broken symmetry and gap structure have remained longstanding riddles. Here we directly image how, across the hidden-order transition, the electronic structure of URu2Si2 abruptly reconstructs. We observe an energy gap of 7 meV opening over 70% of a large diamond-like heavy-fermion Fermi surface, resulting in the formation of four small Fermi petals, and a change in the electronic periodicity from body-centred tetragonal to simple tetragonal. Our results explain the large entropy loss in the hidden-order phase, and the similarity between this phase and the high-pressure antiferromagnetic phase found in quantum-oscillation experiments.

  7. The placebo effect and nothingness

    DEFF Research Database (Denmark)

    Jensen, Tine

    In this paper I shall discuss the placebo effect from a posthuman angle. The placebo effect is a medical conundrum, as it is a medical effect that is produced by “nothing”. Placebo literally means, ”I please”, and the placebo has, among other things, been defined as an inert substance, often...... a calcium pill. Placebos are being used in medical trials to determine how much of the medical effect is caused by other factors than medical. There is a vast amount of literature on the placebo effect and it has been studied since the late 1940’ies, mainly for the purpose of pre-elimination from medical...... trials. It has been studied as an effect of personality traits, as an expectational effect, and from a physiological point of departure. Still it remains a medical riddle how something that is “nothing” can cause a measurable effect? In this paper I shall address this issue from a posthuman angle...

  8. Deposition By Turbidity Currents In Intraslope Diapiric Minibasins: Results Of 1-D Experiments And Numerical Modeling

    Science.gov (United States)

    Lamb, M.; Toniolo, H.; Parker, G.

    2001-12-01

    The slope of the continental margin of the northern Gulf of Mexico is riddled with small basins resulting from salt tectonics. Each such minibasin is the result of local subsidence due to salt withdrawal, and is isolated from neighboring basins by ridges formed due to compensational uplift. The minibasins are gradually filled by turbidity currents, which are active at low sea stand. Experiments in a 1-D minibasin reveal that a turbidity current flowing into a deep minibasin must undergo a hydraulic jump and form a muddy pond. This pond may not spill out of the basin even with continuous inflow. The reason for this is the detrainment of water across the settling interface that forms at the top of the muddy pond. Results of both experiments and numerical modeling of the flow and the evolution of the deposit are presented. The numerical model is the first of its kind to capture both the hydraulic jump and the effect of detrainment in ponded turbidity currents.

  9. Anomalous piezoelectricity in two-dimensional graphene nitride nanosheets.

    Science.gov (United States)

    Zelisko, Matthew; Hanlumyuang, Yuranan; Yang, Shubin; Liu, Yuanming; Lei, Chihou; Li, Jiangyu; Ajayan, Pulickel M; Sharma, Pradeep

    2014-06-27

    Piezoelectricity is a unique property of materials that permits the conversion of mechanical stimuli into electrical and vice versa. On the basis of crystal symmetry considerations, pristine carbon nitride (C3N4) in its various forms is non-piezoelectric. Here we find clear evidence via piezoresponse force microscopy and quantum mechanical calculations that both atomically thin and layered graphitic carbon nitride, or graphene nitride, nanosheets exhibit anomalous piezoelectricity. Insights from ab inito calculations indicate that the emergence of piezoelectricity in this material is due to the fact that a stable phase of graphene nitride nanosheet is riddled with regularly spaced triangular holes. These non-centrosymmetric pores, and the universal presence of flexoelectricity in all dielectrics, lead to the manifestation of the apparent and experimentally verified piezoelectric response. Quantitatively, an e11 piezoelectric coefficient of 0.758 C m(-2) is predicted for C3N4 superlattice, significantly larger than that of the commonly compared α-quartz.

  10. Villa San Michele at Capri – a House with a distinct home for "Genius Loci"

    DEFF Research Database (Denmark)

    Fisker, Anna Marie; Danielsen, Mads Harder

    2012-01-01

    on the spot. When we approached Capri by crossing the Neapolitan bay the first thing our eyes saw was the chapel of San Michele resting high above the blue waters at the top of the steep cliffs - on the edge of the abyss. This place is also the location of the Egyptian Sphinx, half lion, half woman...... that the spirit of the place adjoins a metaphysical core of architecture; and as the very core of architecture could be connected to an absolute truth so it seems that genius loci is related to truth; even though it is a truth that is not directly visible. We ask in this paper if it is a truth that is perennially...... are going to hear the Sphinx ask us questions, all these riddling puzzles, we first have to ask the Sphinx to know how to ask questions. That genius loci are present in architectural theory owes much to the Scandinavian theoretician and architect Christian Norberg-Schulz, who emphasized considerations...

  11. An Introduction to Geometric Algebra with some Preliminary Thoughts on the Geometric Meaning of Quantum Mechanics

    International Nuclear Information System (INIS)

    Horn, Martin Erik

    2014-01-01

    It is still a great riddle to me why Wolfgang Pauli and P.A.M. Dirac had not fully grasped the meaning of their own mathematical constructions. They invented magnificent, fantastic and very important mathematical features of modern physics, but they only delivered half of the interpretations of their own inventions. Of course, Pauli matrices and Dirac matrices represent operators, which Pauli and Dirac discussed in length. But this is only part of the true meaning behind them, as the non-commutative ideas of Grassmann, Clifford, Hamilton and Cartan allow a second, very far reaching interpretation of Pauli and Dirac matrices. An introduction to this alternative interpretation will be discussed. Some applications of this view on Pauli and Dirac matrices are given, e.g. a geometric algebra picture of the plane wave solution of the Maxwell equation, a geometric algebra picture of special relativity, a toy model of SU(3) symmetry, and some only very preliminary thoughts about a possible geometric meaning of quantum mechanics

  12. The ascent of gravity the quest to understand the force that explains everything

    CERN Document Server

    Chown, Marcus

    2017-01-01

    Gravity is the weakest force in the everyday world yet it is the strongest force in the universe. It was the first force to be recognised and described yet it is the least understood. It is a 'force' that keeps your feet on the ground yet no such force actually exists. Gravity, to steal the words of Winston Churchill, is 'a riddle, wrapped in a mystery, inside an enigma'. And penetrating that enigma promises to answer the biggest questions in science: what is space? What is time? What is the universe? And where did it all come from? Award-winning writer Marcus Chown takes us on an unforgettable journey from the recognition of the 'force' of gravity in 1666 to the discovery of gravitational waves in 2015. And, as we stand on the brink of a seismic revolution in our worldview, he brings us up to speed on the greatest challenge ever to confront physics.

  13. Tree ring-based seven-century drought records for the Western Himalaya, India

    Science.gov (United States)

    Yadav, Ram R.

    2013-05-01

    The paucity of available instrumental climate records in cold and arid regions of the western Himalaya, India, hampers our understanding of the long-term variability of regional droughts, which seriously affect the agrarian economy of the region. Using ring width chronologies of Cedrus deodara and Pinus gerardiana together from a network of moisture-stressed sites, Palmer Drought Severity Index values for October-May back to 1310 A.D. were developed. The twentieth century features dominant decadal-scale pluvial phases (1981-1995, 1952-1968, and 1918-1934) as compared to the severe droughts in the early seventeenth century (1617-1640) as well as late fifteenth to early sixteenth (1491-1526) centuries. The drought anomalies are positively (negatively) associated with central Pacific (Indo-Pacific Warm Pool) sea surface temperature anomalies. However, non-stationarity in such relationships appears to be the major riddle in the predictability of long-term droughts much needed for the sustainable development of the ecologically sensitive region of the Himalayas.

  14. Skull base tumors: a kaleidoscope of challenge.

    Science.gov (United States)

    Khanna, J N; Natrajan, Srivalli; Galinde, Jyotsna

    2014-08-01

    Resection of skull base lesions has always been riddled with problems like inadequate access, proximity to major vessels, dural tears, cranial nerve damage, and infection. Understanding the modular concept of the facial skeleton has led to the development of transfacial swing osteotomies that facilitates resection in a difficult area with minimal morbidity and excellent cosmetic results. In spite of the current trend toward endonasal endoscopic management of skull base tumors, our series presents nine cases of diverse extensive skull base lesions, 33% of which were recurrent. These cases were approached through different transfacial swing osteotomies through the mandible, a midfacial swing, or a zygomaticotemporal osteotomy as dictated by the three-dimensional spatial location of the lesion, and its extent and proximity to vital structures. Access osteotomies ensured complete removal and good results through the most direct and safe route and good vascular control. This reiterated the fact that transfacial approaches still hold a special place in the management of extensive skull base lesions.

  15. On Dual Phase-Space Relativity, the Machian Principle and Modified Newtonian Dynamics

    CERN Document Server

    Castro, C

    2004-01-01

    We investigate the consequences of the Mach's principle of inertia within the context of the Dual Phase Space Relativity which is compatible with the Eddington-Dirac large numbers coincidences and may provide with a physical reason behind the observed anomalous Pioneer acceleration and a solution to the riddle of the cosmological constant problem ( Nottale ). The cosmological implications of Non-Archimedean Geometry by assigning an upper impassible scale in Nature and the cosmological variations of the fundamental constants are also discussed. We study the corrections to Newtonian dynamics resulting from the Dual Phase Space Relativity by analyzing the behavior of a test particle in a modified Schwarzschild geometry (due to the the effects of the maximal acceleration) that leads in the weak-field approximation to essential modifications of the Newtonian dynamics and to violations of the equivalence principle. Finally we follow another avenue and find modified Newtonian dynamics induced by the Yang's Noncommut...

  16. Geneva University: Observation of electron-antineutrino disappearance at Daya Bay

    CERN Multimedia

    Université de Genève

    2012-01-01

    GENEVA UNIVERSITY École de physique Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 Genève 4 Tél.: (022) 379 62 73 Fax: (022) 379 69 92 Monday 19 March 2012 COLLOQUE DE PHYSIQUE 5 p.m. - École de Physique, Auditoire Stueckelberg Observation of electron-antineutrino disappearance at Daya Bay  Professor Yifang Wang Institute of High Energy Physics of the Chinese Academy of Sciences Beijing The Daya Bay Reactor Neutrino Experiment, a multinational collaboration operating in the south of China, today reported the first results of its search for the last, most elusive piece of a long-standing puzzle: how is it that neutrinos can appear to vanish as they travel? The surprising answer opens a gateway to a new understanding of fundamental physics and may eventually solve the riddle of why there is far more ordinary matter than antimatter in the Universe today....

  17. Neural pathway in the right hemisphere underlies verbal insight problem solving.

    Science.gov (United States)

    Zhao, Q; Zhou, Z; Xu, H; Fan, W; Han, L

    2014-01-03

    Verbal insight problem solving means to break mental sets, to select the novel semantic information and to form novel, task-related associations. Although previous studies have identified the brain regions associated with these key processes, the interaction among these regions during insight is still unclear. In the present study, we explored the functional connectivity between the key regions during solving Chinese 'chengyu' riddles by using event-related functional magnetic resonance imaging. Results showed that both insight and noninsight solutions activated the bilateral inferior frontal gyri, middle temporal gyri and hippocampi, and these regions constituted a frontal to temporal to hippocampal neural pathway. Compared with noninsight solution, insight solution had a stronger functional connectivity between the inferior frontal gyrus and middle temporal gyrus in the right hemisphere. Our study reveals the neural pathway of information processing during verbal insight problem solving, and supports the right-hemisphere advantage theory of insight. Copyright © 2013 IBRO. Published by Elsevier Ltd. All rights reserved.

  18. Climate change: Some elements from the scientific background and the scientific process; Klimafaglig oppdatering

    Energy Technology Data Exchange (ETDEWEB)

    Alfsen, Knut H [Cicero, Oslo (Norway)

    1998-07-01

    The paper reviews the background on mechanisms behind climate variations in the past and man-made climate change and also briefly what is said by the IPCC (Intergovernmental Panel on Climate Change) about the likely future impact of anthropogenic emission of greenhouse gases. The IPCC is presented in some detail. The problem of climate change is not important mainly because of increased global average temperature, but because of a potential variability and instability of the global climate and the local weather. In the past, the climate system has fluctuated strongly and rapidly for natural causes. But the stable climate regime observed after the last ice age is currently perturbed by the large outpouring of greenhouse gases from a variety of human activities. Can the stability of the current climate regime withstand this disturbance? The problem of climate change is riddled with uncertainties, and our main challenge to this situation is to find out how to respond in a rational way. 19 refs., 15 figs.

  19. The role of private speech in cognitive regulation of learners: The case of English as a foreign language education

    Directory of Open Access Journals (Sweden)

    Mohamad Reza Anani Sarab

    2015-12-01

    Full Text Available Investigations into the use of private speech by adult English foreign language (EFL learners in regulating their mental activities have been an interesting area of research with a sociocultural framework. Following this line of research, 30 advanced adult EFL learners were selected via the administration of Oxford quick placement test and took a test of solving challenging English riddles while their voices were being recorded. Later, instances of the produced private speech were analyzed in terms of form, content, and function. It was demonstrated that private speech with its different forms, contents, and functions plays a very crucial role in cognitive regulation of EFL learners which has important implications for the context of language learning classrooms. In addition, participants seemed to produce qualitatively different kinds of L2 private speech, which brought us to the conclusion that it would be necessary to consider quality and not just quantity in studying psycholinguistic concepts, such as cognitive regulation and private speech.

  20. "A Riddle, Wrapped in a Mystery, inside an Enigma": Teaching Post-Socialist Transformation to UK Students in Moscow

    Science.gov (United States)

    Moran, Dominique; Round, John

    2010-01-01

    In the 20 years since the fall of the Berlin Wall, teaching post-socialist transition to undergraduate students has become increasingly challenging. This paper relates the development, planning and operation of a fieldwork module in Moscow, for Year Three geography undergraduates. It argues that "on-street" teaching and imaginative use…

  1. Computational Identification Raises a Riddle for Distribution of Putative NACHT NTPases in the Genome of Early Green Plants.

    Science.gov (United States)

    Arya, Preeti; Acharya, Vishal

    2016-01-01

    NACHT NTPases and AP-ATPases belongs to STAND (signal transduction ATPases with numerous domain) P-loop NTPase class, which are known to be involved in defense signaling pathways and apoptosis regulation. The AP-ATPases (also known as NB-ARC) and NACHT NTPases are widely spread throughout all kingdoms of life except in plants, where only AP-ATPases have been extensively studied in the scenario of plant defense response against pathogen invasion and in hypersensitive response (HR). In the present study, we have employed a genome-wide survey (using stringent computational analysis) of 67 diverse organisms viz., archaebacteria, cyanobacteria, fungi, animalia and plantae to revisit the evolutionary history of these two STAND P-loop NTPases. This analysis divulged the presence of NACHT NTPases in the early green plants (green algae and the lycophyte) which had not been previously reported. These NACHT NTPases were known to be involved in diverse functional activities such as transcription regulation in addition to the defense signaling cascades depending on the domain association. In Chalmydomonas reinhardtii, a green algae, WD40 repeats found to be at the carboxyl-terminus of NACHT NTPases suggest probable role in apoptosis regulation. Moreover, the genome of Selaginella moellendorffii, an extant lycophyte, intriguingly shows the considerable number of both AP-ATPases and NACHT NTPases in contrast to a large repertoire of AP-ATPases in plants and emerge as an important node in the evolutionary tree of life. The large complement of AP-ATPases overtakes the function of NACHT NTPases and plausible reason behind the absence of the later in the plant lineages. The presence of NACHT NTPases in the early green plants and phyletic patterns results from this study raises a quandary for the distribution of this STAND P-loop NTPase with the apparent horizontal gene transfer from cyanobacteria.

  2. Rasenmähen aus biopsychologischer Disposition Mowing the lawn out of biopsychological disposition

    Directory of Open Access Journals (Sweden)

    Rochus Wolff

    2003-11-01

    Full Text Available Martin van Creveld will in seinem neuen Buch zeigen, dass von einer Unterdrückung der Frau keine Rede sein könne und vielmehr die Frauen das eigentlich privilegierte Geschlecht seien. Basierend auf einem fragwürdigen ‚biopsychologischen‚ Konzept versucht er, die bestehende Geschlechterordnung zu rechtfertigen, und beschreibt sie als ahistorische Wahrheit. Seine Darstellung ist durch methodische Mängel, einen zweifelhaften Umgang mit Quellen und rhetorische Überredungstechniken gekennzeichnet, was auch noch die letzten positiven Ansätze seines Buches, geschlechtsspezifische Benachteiligungen von Männern zu problematisieren, diskreditiert.In his latest book, Martin van Creveld tries to prove that women are not in fact oppressed, but that really they are the privileged sex. Based on a questionable ‚biopsychological’ concept, the author attempts to legitimate the existing order of the sexes by presenting it as ahistorical truth. His reasoning is riddled with methodological faults, a dubious way of dealing with his sources and rhetorical techniques of persuasion which only serve to discredit the few vaild points his book does make about discrimination against men.

  3. Social facilitation of cognition in rhesus monkeys: audience vs. coaction

    Directory of Open Access Journals (Sweden)

    Amélie J. Reynaud

    2015-12-01

    Full Text Available Social psychology has long established that the mere presence of a conspecific, be it an active co-performer (coaction effect, or a passive spectator (audience effect changes behavior in humans. Yet, the process mediating this fundamental social influence has so far eluded us. Brain research and its nonhuman primate animal model, the rhesus macaque, could shed new light on this long debated issue. For this approach to be fruitful, however, we need to improve our patchy knowledge about social presence influence in rhesus macaques. Here, seven adults (two dyads and one triad performed a simple cognitive task consisting in touching images to obtain food treats, alone versus in presence of a co-performer or a spectator. As in humans, audience sufficed to enhance performance to the same magnitude as coaction. Effect sizes were however 4 times larger than those typically reported in humans in similar tasks. Both findings are an encouragement to pursue brain and behavior research in the rhesus macaque to help solve the riddle of social facilitation mechanisms.

  4. One hundred prisoners and a light bulb

    CERN Document Server

    van Ditmarsch, Hans

    2015-01-01

    A group of 100 prisoners, all together in the prison dining area, are told that they will be all put in isolation cells and then will be interrogated one by one in a room containing a light with an on/off switch. The prisoners may communicate with one another by toggling the light switch (and that is the only way in which they can communicate). The light is initially switched off. There is no fixed order of interrogation, or interval between interrogations, and the same prisoner may be interrogated again at any stage. When interrogated, a prisoner can either do nothing, or toggle the light switch, or announce that all prisoners have been interrogated. If that announcement is true, the prisoners will (all) be set free, but if it is false, they will all be executed. While still in the dining room, and before the prisoners go to their isolation cells (forever), can the prisoners agree on a protocol that will set them free? At first glance, this riddle may seem impossible to solve: how can all of the necessary in...

  5. Developing a clinical trial unit to advance research in an academic institution.

    Science.gov (United States)

    Croghan, Ivana T; Viker, Steven D; Limper, Andrew H; Evans, Tamara K; Cornell, Alissa R; Ebbert, Jon O; Gertz, Morie A

    2015-11-01

    Research, clinical care, and education are the three cornerstones of academic health centers in the United States. The research climate has always been riddled with ebbs and flows, depending on funding availability. During a time of reduced funding, the number and scope of research studies have been reduced, and in some instances, a field of study has been eliminated. Recent reductions in the research funding landscape have led institutions to explore new ways to continue supporting research. Mayo Clinic in Rochester, MN has developed a clinical trial unit within the Department of Medicine, which provides shared resources for many researchers and serves as a solution for training and mentoring new investigators and study teams. By building on existing infrastructure and providing supplemental resources to existing research, the Department of Medicine clinical trial unit has evolved into an effective mechanism for conducting research. This article discusses the creation of a central unit to provide research support in clinical trials and presents the advantages, disadvantages, and required building blocks for such a unit. Copyright © 2015 Mayo Clinic. Published by Elsevier Inc. All rights reserved.

  6. Remember Hard but Think Softly: Metaphorical Effects of Hardness/Softness on Cognitive Functions

    Directory of Open Access Journals (Sweden)

    Jiushu Xie

    2016-09-01

    Full Text Available Previous studies have found that bodily stimulation, such as hardness, biases social judgment and evaluation via metaphorical association; however, it remains unclear whether bodily stimulation also affects cognitive functions, such as memory and creativity. The current study used metaphorical associations between hard and rigid and between soft and flexible in Chinese, to investigate whether the experience of hardness affected cognitive functions requiring either rigidity (memory or flexibility (creativity. In Experiment 1, we found that Chinese-speaking participants performed better at recalling previously memorized words while sitting on a hard-surface stool (the hard condition than a cushioned one (the soft condition. In Experiment 2, participants sitting on a cushioned stool outperformed those sitting on a hard-surface stool on a Chinese riddle task, which required creative/flexible thinking, but not on an analogical reasoning task, which required both rigid and flexible thinking. The results suggest the hardness experience affects cognitive functions that are metaphorically associated with rigidity and flexibility. They support the embodiment proposition that cognitive functions and representations could be grounded via metaphorical association in bodily states.

  7. Heaven and Earth in Ancient Greek Cosmology From Thales to Heraclides Ponticus

    CERN Document Server

    Couprie, Dirk L

    2011-01-01

    In Miletus, about 550 B.C., together with our world-picture cosmology was born. This book tells the story. In Part One the reader is introduced in the archaic world-picture of a flat earth with the cupola of the celestial vault onto which the celestial bodies are attached. One of the subjects treated in that context is the riddle of the tilted celestial axis. This part also contains an extensive chapter on archaic astronomical instruments. Part Two shows how Anaximander (610-547 B.C.) blew up this archaic world-picture and replaced it by a new one that is essentially still ours. He taught that the celestial bodies orbit at different distances and that the earth floats unsupported in space. This makes him the founding father of cosmology. Part Three discusses topics that completed the new picture described by Anaximander. Special attention is paid to the confrontation between Anaxagoras and Aristotle on the question whether the earth is flat or spherical, and on the battle between Aristotle and Heraclid...

  8. Passport to the Big Bang moves across the road

    CERN Document Server

    Corinne Pralavorio

    2015-01-01

    The ATLAS platform of the Passport to the Big Bang circuit has been relocated in front of the CERN Reception.   The ATLAS platform of the Passport to the Big Bang, outside the CERN Reception building. The Passport to the Big Bang platform of the ATLAS Experiment has been moved in front of the CERN Reception to make it more visible and accessible. It had to be dismantled and moved from its previous location in the garden of the Globe of Science and Innovation due to the major refurbishment work in progress on the Globe, and is now fully operational in its new location on the other side of the road, in the Main Reception car-park. The Passport to the Big Bang circuit, inaugurated in 2013, comprises ten platforms installed in front of ten CERN sites and aims to help local residents and visitors to the region understand CERN's research. Dedicated Passport to the Big Bang flyers, containing all necessary information and riddles for you to solve, are available at the CERN Rec...

  9. The Opium Must Go Thru The Opium Must Go Thru

    Directory of Open Access Journals (Sweden)

    Anita Flanders Rebello

    2008-04-01

    Full Text Available In The Opium Must Go Thru, Charles Potts' "potty" poetic prose puns away in an irreverential anti-civilization protest against everything that is new-old to sublime the old-new - but the dark and light of Yin and Yang are the same that bothered Shakespeare in his day. This book, as the drawings by Robert McNealy illustrate, is a mad socio-economic philosophic chess game. . . an intel lectual whooped up hippy riddle. You ask yourself if Potts is a brain or a bum. The words and the thought behind the words are an exasperating jumble, until you get the "beat" - the mood - maybe a couple of beers, a little "pot". . . No,that won't help because it's too haphardly logical "The water buffalo who bailed out the hot green house once turned to an underfucked cow and murmured "Nobody here understands what I say". And Potts can jump from this hurly-burly into crystal clear statements such as, "But the children can think circles around them. Children have always been the redeemers."

  10. A new beginning

    Directory of Open Access Journals (Sweden)

    John A Martignetti

    2011-03-01

    Full Text Available John A MartignettiMount Sinai School of Medicine, Departments of Genetics and Genomic Science, Pediatrics, and Oncological Sciences, New York, USAIf you, as Oedipus was, were a traveler in ancient Thebes you may have been met by a perched chimeric interrogator posing a question only slightly more foreboding than “Why a new genetics journal?” The mythical Sphinx, literally interpreted as representing the old pre-Olympian culture on the precipice of replacement, guarded the entrance to Thebes, and asked a riddle of all travelers prior to granting them entry.“Which creature is it that in the morning goes on four legs, at midday on two, and in the evening upon three?”Similarly, as you question why submit your work to, or review for, and indeed, even become the Editor-in-Chief of a new online access journal a sense of fear may overwhelm. While the Sphnix’s punishment of being torn asunder and devoured may at least seem quick and to the point, would the efforts of being part of a new endeavor somehow be more inhumane.

  11. Save our inboxes! Use e-mail wisely

    CERN Multimedia

    Achintya Rao

    2013-01-01

    At CERN, with collaborators all over the world, e-mail is inevitably the primary means of communication: we use it for everything from coordinating projects to organising lunches. But e-mail can also be one of the most inefficient means of communication we have! Here's how to fix it.   Let’s get straight to the point: we receive too many e-mails. Think about all the e-mails that you deleted without a second thought. Think about the times you’ve unnecessarily been in CC. Take a look at the unread e-mails sitting in your inbox at this very moment, ones that you have no intention of ever looking at. You can, however, tame this overload with a few simple measures and turn e-mail into an important communication and productivity tool. Many recommendations for improving e-mail etiquette suggest an abrasive approach riddled with bullet points. In a vastly multi-cultural setting such as CERN, however this approach may fail. So, here are a few dos and don’ts based o...

  12. Review of the analysis of relics associated with the HMAS Sydney II

    Energy Technology Data Exchange (ETDEWEB)

    Treasure, Alana, E-mail: alana.treasure@awm.gov.a [Collection Services, Australian War Memorial, Canberra (Australia); Bailey, George; Challenor, Catherine [Collection Services, Australian War Memorial, Canberra (Australia); Otieno-Alego, Vincent [Forensic and Data Centres, Australian Federal Police, Canberra (Australia); Creagh, Dudley [Faculty of Applied Science, University of Canberra, Canberra (Australia)

    2010-07-21

    The 1941 sinking of the HMAS Sydney II in action with the German raider KSN Kormoran off the coast of Western Australia has been a source of mystery and speculation for more than 60 years. HMAS Sydney II was lost with all hands. The largest item of flotsam found in the vicinity was a Carley float, which was riddled with holes some of which contained small metallic items. The float was subjected to various physical and elemental examination methods in 1992 in an attempt to determine what may have happened. Three months after sinking, the unidentified body of a man washed ashore at Christmas Island in another Carley float. Relics found in his unmarked grave in 2006 included several degraded and corroded press-studs, some containing fragments of fabric. A metal fragment was recovered from the man's skull. XRF, SEM-EDS, Raman and FTIR spectroscopy, and X-ray tomography analysis of these items was conducted in an attempt to determine what link the sailor may have to the HMAS Sydney II.

  13. Menyoal Kembali Teori Evolusi Agama J.G. Frazer dalam Keberagamaan Masyarakat Jawa

    Directory of Open Access Journals (Sweden)

    Muhammad Rikza Muqtada

    2016-06-01

    Full Text Available Religion is seen as the result of philosophers’ thinking production which has a tendency to solve the riddle of life and to spread their ideas and their thoughts to others. Frazer is one pushed for discovering when the religion began to exist. The conclusion is that the human belief system, in accordance with a level of reasoning ability, evolves from magical belief, than religous belief, and ends on science. Nevertheless, when it is compared to the religious phenomenon in Indonesia, especially in Java, Frazer’s theory is not entirely true and debatable. The religious system in Java exactly does not have evolution as interpreted in Frazer’s theory. With its elasticity, genuine Javanese belief – dynamism and animism – only underwent assimilation with foreign cultures that came later like Islam and Christian, and including Western culture. In the context of Javanese religiosity, those three beliefs system as intended by Frazer, take place integrally and parallel in modern Javanese culture.

  14. Study of II Galactic quadrant of Milky Way Galaxy using open clusters

    Science.gov (United States)

    Bisht, Devendra; Ganesh, Shashikiran; Baliyan, Kiran Singh; Yadav, Ramakant Singh; Durgapal, Alok

    2018-04-01

    We have made UBV I CCD observations for the open clusters Teutsch 1, Riddle 4 and Czernik 6 using 1.04-m Sampurnanand telescope located at the ARIES observatory (Manora peak, Nainital, India). We have used 2MASS JHKS data for the clusters Teutsch 126, Teutsch 54 and Czernik 3. For the estimation of fundamental parameters, we have plotted radial density profiles, colour-magnitude and colour-colour diagrams. Using these inputs, we have studied the structure of Milky Way Galaxy in the second Galactic quadrant. We have considered the open clusters that are younger than 1 Gyrs and lay in the longitude range from 90 to 180 deg. Our study shows that up to 3.5 Kpc, the Galactic disc bends towards the southern hemisphere while after 3.5 Kpc it bends towards the northern hemisphere. The distribution of reddening with longitude and age shows a decreasing trend with the longitude and age of the clusters. Our study also indicates that younger clusters have more reddening than older ones.

  15. Scream, cultura popular y el feminismo de la tercera ola: "Yo no soy mi madre"

    Directory of Open Access Journals (Sweden)

    Kathleen Rowe Karlyn

    2005-01-01

    Full Text Available This paper analyzes Wes Craven’s horror trilogy Scream; the trilogy, like all popular texts, is riddled with contradictions about women’s representation that beg a careful analysis based on an informed understanding of media culture and representation, of history, and of the issues that matter to young women today. My reading of the film draws up the connections between Third Wave feminism and popular culture in order to show how these films provide a rich opportunity to study the contradictions and possibilities of feminism in a postmodern age. The purpose here is not to mount an unconditional defense of popular culture, but to argue that women who care about the next generation of girls need to learn more about the popular texts they're drawn to. If a productive conversation is going to happen among women of all ages about the future of the feminist movement, it will have to take place on the terrain of popular culture where young women today are refashioning feminism toward their own ends.

  16. THE EUROPEAN UNION AND RUSSIA, COOPERATION OR COMPETITION?

    Directory of Open Access Journals (Sweden)

    Loredana Maria SIMIONOV

    2014-10-01

    Full Text Available The unfolding events in the Ukraine remind us of Georgia 2008 and make us wonder whether their impact and implications on the EU – Russia relations will be as deep and long-lasting. Although it is too soon to ponder on the implications of these events, we can already perceive the wave of tensions and disagreements that is spreading all around the European continent; tensions that once more prove that proper economic cooperation between the two actors is merely impossible to consider without taking into account the political ties between them. How can the EU enhance greater cooperation with Russia and solve Churchill’s "riddle, wrapped in a mystery, inside an enigma"? Is the European Union vulnerable politically due to its energy dependence on Russia? Is the Russian economy dependent solely on its European consumers? Whose behaviour is more rational? Who holds the upper hand? This paper will focus on answering all these questions by analysing both actors in terms of power and will particularly highlight their paradigms, perceptions, needs and expectations from one another.

  17. Mozart: the toothache of a genius.

    Science.gov (United States)

    Eramo, Stefano; Gallottini, Livio; Migliau, Guido

    2011-01-01

    The medical history of Wolfgang Amadeus Mozart (1756-1791) has been pieced together from his letters and from anecdotes, but his dental health is one aspect which has been somewhat overlooked. It is known that, from an early age, he suffered from toothache and tooth abscesses, problems that may even have had other medical repercussions. In this paper, the authors explore and consider whether these negative experiences might have influenced Mozart's work and his attitude to teeth and dental pathologies. Two pieces of evidence from the life and work of this great composer provide clues: the aria entitled "A tooth decayed and sensitive to cold" (KV 209 a) (1772), containing the lament of a "sick man" suffering from toothache; and the first of the "Zoroastrian Riddles," which Mozart proposed during a masked ball in 1786, and whose solution is "teeth." Close examination of these two creative feats demonstrate that Mozart's attitude toward dental pathologies was calm and rational, so much so that he even managed to use the topic as a source of inspiration for a small jewel of a composition.

  18. CH{sup +} and SH{sup +} in the diffuse interstellar medium: Tracers of turbulent dissipation

    Energy Technology Data Exchange (ETDEWEB)

    Edith, Falgarone; Maryvonne, Gerin; Massimo, De Luca [Observatoire de Paris and Ecole Normale Supérieure, Paris (France); Benjamin, Godard [Centro de Astrobiologia, CSIC-INTA, Madrid (Spain)

    2015-01-22

    Absorption spectroscopy performed with Herschel/HIFI against the dust continuum emission of bright galactic star-forming regions has allowed the detection of the ground-state transitions of several hydride cations, CH{sup +}, OH{sup +}, H{sub 2}O{sup +}, and SH{sup +} in the intervening diffuse medium. These hydrides, that need H{sub 2} to form but are also destroyed by H{sub 2}, appear to be most sensitive tracers of a poorly known component of the interstellar medium (ISM): molecular gas weakly shielded from UV radiation. Among them, because their formation routes are so highly endoenergic, the CH{sup +} and SH{sup +} cations are proposed to be specific tracers of turbulent dissipation occurring in diffuse gas. Their elusive origin in the diffuse ISM is therefore much more than a chemical riddle: it is rooted in the physics of the diffuse ISM, its turbulent dissipation rate and connects with the far broader issue of galaxy evolution. The Herschel/HIFI observations of CH{sup +} and SH{sup +} are compared with the predictions of chemical models that include the non-equilibrium effects of turbulent dissipation.

  19. CH+ and SH+ in the diffuse interstellar medium: Tracers of turbulent dissipation

    International Nuclear Information System (INIS)

    Edith, Falgarone; Maryvonne, Gerin; Massimo, De Luca; Benjamin, Godard

    2015-01-01

    Absorption spectroscopy performed with Herschel/HIFI against the dust continuum emission of bright galactic star-forming regions has allowed the detection of the ground-state transitions of several hydride cations, CH + , OH + , H 2 O + , and SH + in the intervening diffuse medium. These hydrides, that need H 2 to form but are also destroyed by H 2 , appear to be most sensitive tracers of a poorly known component of the interstellar medium (ISM): molecular gas weakly shielded from UV radiation. Among them, because their formation routes are so highly endoenergic, the CH + and SH + cations are proposed to be specific tracers of turbulent dissipation occurring in diffuse gas. Their elusive origin in the diffuse ISM is therefore much more than a chemical riddle: it is rooted in the physics of the diffuse ISM, its turbulent dissipation rate and connects with the far broader issue of galaxy evolution. The Herschel/HIFI observations of CH + and SH + are compared with the predictions of chemical models that include the non-equilibrium effects of turbulent dissipation

  20. The synthesis and pharmacological evaluation of (±-2,3-seco-fentanyl analogues

    Directory of Open Access Journals (Sweden)

    LJ. DOSEN-MICOVIC

    2004-11-01

    Full Text Available An efficient, five-step synthetic approach to various acyclic 1,3-diamines has been developed and applied to the preparation of a novel class of open-chained fentanyl analogues. The acyclic derivatives 5.1–5.5 (all new compounds were synthesized with the aim of estimating the significance of the piperidine ring for the opioid analgesic activity of anilido-piperidines. The starting b-keto-amide 1.1, prepared by the aminolysis of methyl acetoacetate with methylphenethylamine, (93 % yield, was successively reacted with NaH and BuLi, to form the highly reactive a,g-dienolate anion 1.1a. Regio and chemoselective g-alkylation of the dienolate with various primary and secondary alkyl halides furnished the b-keto-amides 1.2–1.5 (76–91 %. Reductive amination of the keto-amides 1.1–1.5 with aniline and Zn powder in acetic acid, via the enamine intermediates 2.1–2.5, afforded the b-anilino amides 3.1–3.5 (74–85 %. After reductive deoxygenation of the tertiary amide group, using in situ generated diborane, the corresponding 1,3-diamines 4.1–4.5 were obtained (87–97 %. The synthesis of (±-2,3-seco-fentanyls 5.1–5.5 was completed by N-acylation of the diamines 4.1–4.5 with propionyl chloride, followed by precipitation of the monooxalate salts (86–95 %. The parent compound, 2,3-seco-fentanyl 5.1, was found to be a 40 times less potent narcotic analgesic than fentanyl but still 5–6 times more active than morphine in rats, while i-Pr derivative 5.3 was inactive. Apart from the pharmacological significance, the general procedure described herein may afford various functionalized, 1,3-diamines as potential complexing agents and building blocks for the synthesis of aza-crown ethers.

  1. Staging Memory: The Drama Inside the Language of Elfriede Jelinek

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    Gita Honegger

    2007-01-01

    Full Text Available This essay focuses on Jelinek's problematic relationship to her native Austria, as it is reflected in some of her most recent plays: Ein Sportstück (A Piece About Sports, In den Alpen (In the Alps and Das Werk (The Plant. Taking her acceptance speech for the 2004 Nobel Prize for Literature as a starting point, my essay explores Jelinek's unique approach to her native language, which carries both the burden of historic guilt and the challenge of a distinguished, if tortured literary legacy. Furthermore, I examine the performative force of her language. Jelinek's "Dramas" do not unfold in action and dialogue, rather, they are embedded in the grammar itself. Her radically subversive vision of Austrian culture reveals her own deep roots in it and the obsessive longing to align herself with its purest and martyred voices—from Hugo von Hofmannsthal to Paul Celan. Against the exploitation by contemporary tourism of a landscape that is riddled with the undead of political and commercial crimes, against the pollution and perversion of official language, Jelinek's linguistic experiments, destructive and anti-traditional at first sight, are urgently conservative projects.

  2. Project-Based Approach in a First-Year Engineering Course to Promote Project Management and Sustainability

    Directory of Open Access Journals (Sweden)

    Pooya Taheri

    2018-05-01

    Full Text Available To safeguard the environment and satisfy the energy needs of the present, without compromising the ability of future generations to do the same, sustainable energy development is urgently needed. This complex task is riddled with social, political, scientific, technical, and environmental challenges. Education is essential if we are to meet the energy demands of the world in the most sustainable manner available to us. Langara College offers a first-year engineering course that is meant to introduce students to engineering design and case studies, in addition to providing a brief glance on the history, ethics, and the different disciplines of engineering (APSC 1010. Using a project-based learning approach that promotes teamwork and research, this course uses a variety of instructional methods including lectures, class discussions, and guest appearances by experts in their fields. Introductions to technical concepts, such as soldering, 3D printing, and microcontroller, are also addressed in this course. This paper demonstrates how this, or similar courses, are optimized to raise awareness of the sustainability issues this planet is facing. Learning outcomes are evaluated using an anonymous student survey which demonstrates how the students’ project-management and presentation skills have improved.

  3. Observing Tsunamis in the Ionosphere Using Ground Based GPS Measurements

    Science.gov (United States)

    Galvan, D. A.; Komjathy, A.; Song, Y. Tony; Stephens, P.; Hickey, M. P.; Foster, J.

    2011-01-01

    Ground-based Global Positioning System (GPS) measurements of ionospheric Total Electron Content (TEC) show variations consistent with atmospheric internal gravity waves caused by ocean tsunamis following recent seismic events, including the Tohoku tsunami of March 11, 2011. We observe fluctuations correlated in time, space, and wave properties with this tsunami in TEC estimates processed using JPL's Global Ionospheric Mapping Software. These TEC estimates were band-pass filtered to remove ionospheric TEC variations with periods outside the typical range of internal gravity waves caused by tsunamis. Observable variations in TEC appear correlated with the Tohoku tsunami near the epicenter, at Hawaii, and near the west coast of North America. Disturbance magnitudes are 1-10% of the background TEC value. Observations near the epicenter are compared to estimates of expected tsunami-driven TEC variations produced by Embry Riddle Aeronautical University's Spectral Full Wave Model, an atmosphere-ionosphere coupling model, and found to be in good agreement. The potential exists to apply these detection techniques to real-time GPS TEC data, providing estimates of tsunami speed and amplitude that may be useful for future early warning systems.

  4. Remember Hard But Think Softly: Metaphorical Effects of Hardness/Softness on Cognitive Functions

    Science.gov (United States)

    Xie, Jiushu; Lu, Zhi; Wang, Ruiming; Cai, Zhenguang G.

    2016-01-01

    Previous studies have found that bodily stimulation, such as hardness biases social judgment and evaluation via metaphorical association; however, it remains unclear whether bodily stimulation also affects cognitive functions, such as memory and creativity. The current study used metaphorical associations between “hard” and “rigid” and between “soft” and “flexible” in Chinese, to investigate whether the experience of hardness affects cognitive functions whose performance depends prospectively on rigidity (memory) and flexibility (creativity). In Experiment 1, we found that Chinese-speaking participants performed better at recalling previously memorized words while sitting on a hard-surface stool (the hard condition) than a cushioned one (the soft condition). In Experiment 2, participants sitting on a cushioned stool outperformed those sitting on a hard-surface stool on a Chinese riddle task, which required creative/flexible thinking, but not on an analogical reasoning task, which required both rigid and flexible thinking. The results suggest the hardness experience affects cognitive functions that are metaphorically associated with rigidity or flexibility. They support the embodiment proposition that cognitive functions and representations can be grounded in bodily states via metaphorical associations. PMID:27672373

  5. Acoustic Impedance Inversion of Seismic Data Using Genetic Algorithm

    Science.gov (United States)

    Eladj, Said; Djarfour, Noureddine; Ferahtia, Djalal; Ouadfeul, Sid-Ali

    2013-04-01

    The inversion of seismic data can be used to constrain estimates of the Earth's acoustic impedance structure. This kind of problem is usually known to be non-linear, high-dimensional, with a complex search space which may be riddled with many local minima, and results in irregular objective functions. We investigate here the performance and the application of a genetic algorithm, in the inversion of seismic data. The proposed algorithm has the advantage of being easily implemented without getting stuck in local minima. The effects of population size, Elitism strategy, uniform cross-over and lower mutation are examined. The optimum solution parameters and performance were decided as a function of the testing error convergence with respect to the generation number. To calculate the fitness function, we used L2 norm of the sample-to-sample difference between the reference and the inverted trace. The cross-over probability is of 0.9-0.95 and mutation has been tested at 0.01 probability. The application of such a genetic algorithm to synthetic data shows that the inverted acoustic impedance section was efficient. Keywords: Seismic, Inversion, acoustic impedance, genetic algorithm, fitness functions, cross-over, mutation.

  6. The Cape Times's portrayal of school violence

    Directory of Open Access Journals (Sweden)

    Corene de Wet

    2016-05-01

    Full Text Available This study explores the Cape Times's portrayal of school violence in the Western Cape (WC, South Africa, reporting on findings from a qualitative content analysis of 41 news articles retrieved from the SA Media database. The findings shed light on the victims and their victimisation, the perpetrators, as well as the context of the violence, identifying gangsterism, as well as school administrative and community factors as the reasons for violence in WC schools. It is argued that school violence and gangsterism are inextricably linked to the Cape Flats in particular, and that the interaction of forms of inequality and oppression such as racism, class privilege and gender oppression are structural root causes for school violence in this area of the WC. The study highlights the negative consequences of school violence on teaching and learning and on the economy. It is concluded that even if the Cape Times paints an exaggerated and atypical picture of violence in the gang-riddled parts of the WC, the detrimental effects thereof on the regions cannot be denied. The study therefore recommends a holistic approach to addressing the structural root causes of school violence where it takes place in the WC.

  7. Innovations in Endosurgery-Journey into the Past of the Future: To Ride the SILS Bandwagon or Not?

    Science.gov (United States)

    Agarwal, Brij B; Chintamani; Ali, Kamran; Goyal, Karan; Mahajan, Krishan C

    2012-06-01

    Progress in surgical practice has paralleled the civilizational evolution. Surgery has progressed from being the last resort in saving life to being form and function preserver. Post-renaissance Industrial age gave an impetus to this march of surgery. The currently on going digital technological revolution has further catalysed this march. Having achieved the stabilized and acceptable clinical outcomes, the surgeon has embarked on a journey of improving patient reported outcomes (PRO). Improvement in PROs with the advent of laparoscopic surgery with the attendant emphasis on minimising invasion has led to debates about invasion being just parietal or holistic in physiological sense. There is a concern that parietal invasiveness shouldn't be a trade-off for compromised clinical outcomes. Single Incision Laparoscopic Surgery (SILS) in its current avatar with current instrumentation seems to be an enthusiastic bandwagon rolling on with the cosmetic benefits acting as veil to hide the potential clinical concerns. History of surgical innovations is riddled with tales of vindictiveness and vicissitude. Lest the same fate befalls SILS we would do better to examine the SILS bandwagon in its current form till the emerging technologies address the current concerns.

  8. Boycotting by paying only parts of the rate because the electricity supplied is generated by nuclear power plants

    International Nuclear Information System (INIS)

    Lueke, G.

    1979-01-01

    The Amtsgericht (lowest civil and criminal court) Stuttgart dismissed the action for payment filed by the public utility for being unfounded for the time being. In contrast to cases decided in Hamburg, an action has been filed to set aside the partial operating license granted for the nuclear power station, and a decision on the issue has not yet been made. Furthermore, the fuel cycle centre at Gorleben is not being built. Therefore, it is open to question whether the operating license can be maintained. Due to the monopoly of power supply, the only way to influence the decision of the plaintiff is to lay a lien on her. This does not apply if the operating license is maintained by a final decision. In the comment, the decision is said to be incorrect and riddled with errors. E.g., the obligation to generate electricity in a harmless way is a duty to public good, i.e., it is not an additional obligation under a contract allowing to lay a lien. Besides, the operating license is effective until it is perhaps revoked. Furthermore, it is examined how the error-containing decision may be abolished. (HSCH) [de

  9. Disruption of SMIM1 causes the Vel− blood type

    Science.gov (United States)

    Ballif, Bryan A; Helias, Virginie; Peyrard, Thierry; Menanteau, Cécile; Saison, Carole; Lucien, Nicole; Bourgouin, Sébastien; Le Gall, Maude; Cartron, Jean-Pierre; Arnaud, Lionel

    2013-01-01

    Here, we report the biochemical and genetic basis of the Vel blood group antigen, which has been a vexing mystery for decades, especially as anti-Vel regularly causes severe haemolytic transfusion reactions. The protein carrying the Vel blood group antigen was biochemically purified from red blood cell membranes. Mass spectrometry-based de novo peptide sequencing identified this protein to be small integral membrane protein 1 (SMIM1), a previously uncharacterized single-pass membrane protein. Expression of SMIM1 cDNA in Vel− cultured cells generated anti-Vel cell surface reactivity, confirming that SMIM1 encoded the Vel blood group antigen. A cohort of 70 Vel− individuals was found to be uniformly homozygous for a 17 nucleotide deletion in the coding sequence of SMIM1. The genetic homogeneity of the Vel− blood type, likely having a common origin, facilitated the development of two highly specific DNA-based tests for rapid Vel genotyping, which can be easily integrated into blood group genotyping platforms. These results answer a 60-year-old riddle and provide tools of immediate assistance to all clinicians involved in the care of Vel− patients. PMID:23505126

  10. The fuzzy cluster analysis of terracotta warriors and horses of Qin Shihuang's mausoleum in pit No.3

    International Nuclear Information System (INIS)

    Zhao Weijuan; Gao Zhengyao; Li Guoxia; Xie Jianzhong; Han Guohe

    2003-01-01

    Terracotta warriors and horses of Qin Shihuang's mausoleum is famous in the world, but their original place of raw material is still a riddle up to now. A total of 44 samples of pottery warriors and horses of Qin Shihuang's mausoleum in pit No.3, 20 samples of clay nearby Museum of the Terracotta Warriors and Horses of Qin Shihuang's Mausoleum, one sample of Yaozhou porcelain body are selected for analysis. The contents of 32 micro elements in these samples are measured by neutron activation analysis (NAA). These data are analyzed by fuzzy cluster analysis, and the trend cluster analysis diagram is obtained. The results show that in terms of chemical composition of the microelements the terracotta warriors and horses from pit No.3 are close to loam soil layer nearby Qin Shihuang's mausoleum, but become estranged from loess layers, and have no relation to Yaozhou porcelain body. Thus it is reasonable to deduce that the Lishan may be considered as the original place of raw materials of the terracotta warriors and horses of Qin Shihuang's mausoleum, and the kiln sites may be also neighborhood of Qin Shihuang's mausoleum

  11. "It´s incredible how much I´ve had to fight." Negotiating medical uncertainty in clinical encounters.

    Science.gov (United States)

    Lian, Olaug S; Robson, Catherine

    2017-01-01

    Clinical encounters related to medically unexplained physical symptoms (MUPS) are associated with high levels of conflict between patients and doctors. Collaborative difficulties are fused by the medical uncertainty that dominates these consultations. The main aim of this study is to explore the interactional dynamics of clinical encounters riddled by medical uncertainty, as experienced by people living with long-term medically unexplained fatigue in Norway. A qualitative thematic analysis of written texts from 256 study participants. We found that patients experience being met with disbelief, inappropriate psychological explanations, marginalisation of experiences, disrespectful treatment, lack of physical examination and damaging health advice. The main source of their discontent is not the lack of biomedical knowledge, but doctors who fail to communicate acknowledgement of patients' experiences, knowledge and autonomy. War metaphors are emblematic of how participants describe their medical encounters. The overarching storyline depicts experiences of being caught in a power struggle with doctors and health systems, fused by a lack of common conceptual ground. When physical symptoms cannot be detected, explained and managed by biomedical knowledge and technology, good doctor-patient partnerships are crucial. Without clearly acknowledging patients' perspectives and capabilities in clinical practice, such partnerships cannot be achieved.

  12. Athermal brittle-to-ductile transition in amorphous solids.

    Science.gov (United States)

    Dauchot, Olivier; Karmakar, Smarajit; Procaccia, Itamar; Zylberg, Jacques

    2011-10-01

    Brittle materials exhibit sharp dynamical fractures when meeting Griffith's criterion, whereas ductile materials blunt a sharp crack by plastic responses. Upon continuous pulling, ductile materials exhibit a necking instability that is dominated by a plastic flow. Usually one discusses the brittle to ductile transition as a function of increasing temperature. We introduce an athermal brittle to ductile transition as a function of the cutoff length of the interparticle potential. On the basis of extensive numerical simulations of the response to pulling the material boundaries at a constant speed we offer an explanation of the onset of ductility via the increase in the density of plastic modes as a function of the potential cutoff length. Finally we can resolve an old riddle: In experiments brittle materials can be strained under grip boundary conditions and exhibit a dynamic crack when cut with a sufficiently long initial slot. Mysteriously, in molecular dynamics simulations it appeared that cracks refused to propagate dynamically under grip boundary conditions, and continuous pulling was necessary to achieve fracture. We argue that this mystery is removed when one understands the distinction between brittle and ductile athermal amorphous materials.

  13. On Performative Philosophy – 10 impulses for discussion from [soundcheck philosophie

    Directory of Open Access Journals (Sweden)

    Eva Maria Gauß

    2015-04-01

    Full Text Available Since 2011, the philosophy-performance festival, [soundcheck philosophie] has been gathering protagonists in German-speaking countries, who seek and intend to cultivate a certain practice in philosophy. This practice takes philosophy - focussing not only on written texts but also on the fundamental oral situations that take place within pilosophy - and presents it artistically and/or through media. In this context. The term ‘Performative Philosophy’ is meant as a working concept for finding criteria and developing contemporary expressions and forms of doing pilosophy. The [soundcheck philosophie] festival and the association responsible for it, Expedition Philosophie / Internationale Gesellschaft für Performative Philosophie, are understood as a forum for discourse. The 10 theses at the end of this article are intended to initiate discussion. Informed by the well-known yet unique structure of an oral conversation, where a lot of things are mentioned out of context and the topic often remains to be discovered, we would also like to contribute impulses for conversation. With this in mind, we have incorporated 10 conversational impulses that answer, tell, ask, state, chat, riddle and reflect about the undertaking of the project of Performative Philosophy.

  14. Healing Trauma and Reasserting Identity through Remembrance in Joanne Fedler’s The Dreamcloth

    Directory of Open Access Journals (Sweden)

    Abdullah Md Abu Shahid

    2017-07-01

    Full Text Available The aim of this article is to analyse the role of memory in generating, transmitting and coming to terms with trauma, and the importance of exploring history, and talking about and sharing traumatic events in the process of healing in Joan Fedler’s The Dreamcloth (2005. In the novel, Maya’s memories of her unrequited lesbian relationship with her beloved Rochel, oppression by the traditional structures of her family and Jewish community, her forced marriage with Yankel, and her being raped by him are responsible for her trauma on a personal level, whereas her forced relocation to South Africa in order to flee from the Holocaust is responsible for her trauma on a communal level. Mia, the protagonist and the grand-daughter of Maya, suffers from the transgenerational trauma of her grandmother, is haunted by her ghost, and also symbolically represents the traumatized Jewish community. She cannot relate to her own Jewish South African identity and thus tries to avoid being reminded of her historical background. Mia recovers from her trauma by exploring her history, solving the riddles of the past and sharing the traumatic memories of the past.

  15. In vivo comparative study of ocular vasodilation, a relative indicator of hyperemia, in guinea pigs following treatment with bimatoprost ophthalmic solutions 0.01% and 0.03%

    Directory of Open Access Journals (Sweden)

    Abayomi B Ogundele

    2010-06-01

    Full Text Available Abayomi B Ogundele, David Earnest, Marsha A McLaughlinAlcon Research, Limited, Fort Worth, TX, USAObjective: The objective of this in vivo study was to compare the incidence of vasodilation in guinea pigs following topical administration of bimatoprost ophthalmic solutions 0.01% and 0.03%.Methods: The study comprised 20 guinea pigs assigned to 2 treatment groups (10 per treatment group to receive either bimatoprost 0.01% or bimatoprost 0.03%. Animals were hand-held under 2.75 × magnification to score ocular vasodilation (a measure of hyperemia, using a scoring system developed at Alcon Research, Ltd. Following baseline ocular scoring, each animal received a 30 μL dose to the left eye of either bimatoprost 0.01% (3 μg or bimatoprost 0.03% (9 μg. Vasodilation was again scored at 1, 2, 3, 4, 5 and 6 hours after dosing. Incidence of vasodilation was calculated as the percent of total eyes in each 2-hour time interval with scores ≥2.Results: The incidence of vasodilation was higher in the bimatoprost 0.01% treatment group (range, 45.0% to 60.0% than the bimatoprost 0.03% treatment group (range, 30.0% to 52.2% at all post-dosing time points.Conclusion: The 2 bimatoprost formulations elicited ocular vasodilation of long duration (>6 hours in the guinea pig model, with the bimatoprost 0.01% treatment group showing a higher incidence of ocular vasodilation than the bimatoprost 0.03% treatment group. Further clinical studies would be needed to determine whether the higher incidence of vasodilation may also be attributed to the increased BAK concentration in the bimatoprost 0.01% formulation.Keywords: bitamoprost, ocular vasodilation, hyperemia

  16. Los sistemas intertextuales transmedia como estrategia pedagógica: De The Walking Dead® a La Odisea

    Directory of Open Access Journals (Sweden)

    Diego Montoya Bermúdez

    2015-10-01

    Full Text Available El presente artículo asume el estudio del fenómeno transmedia como un conjunto de relaciones intertextuales que involucra no sólo condiciones narrativas, sino también antropológicas, con dos objetivos: primero, el de estructurar un sistema intertextual que sirva de herramienta para el análisis de productos transmedia propios de la industria cultural; y segundo, el de generar claves posibles de ser usadas como estrategia pedagógica en el aula de clases para motivar la lectura y escritura en conjunto con otros sistemas simbólicos. Así, el artículo introduce al lector en el fenómeno de la transmedialidad, el cual es posteriormente revisado a partir de las propuestas de Henry Jenkins y Marsha Kinder que nos sirven como material para la elaboración de un Sistema Intertextual Transmedial, el cual se aplica como metodología para el análisis de un caso de la industria del entretenimiento, The Walking Dead®. A partir de lo anterior y a manera de resultados, el texto identifica claves propias de este tipo de sistemas transmediales, las cuales son aplicadas como estrategias pedagógicas para la enseñanza en los niveles de educación básica secundaria y media en los colegios, como se evidenciará en el estudio a La Odisea. Finalmente, a modo de conclusión expone la importancia de explorar las posibilidades que ofrece el estudio y la reflexión transmedial en ámbitos que trasciendan el mundo del entretenimiento.

  17. A narrative analysis of helplessness in depression.

    Science.gov (United States)

    Vanheule, Stijn; Hauser, Stuart T

    2008-12-01

    The transcripts of semistructured clinical interviews with forty psychiatrically hospitalized adolescents were subjected to narrative analysis in an effort to map the logic of their explanations as they spontaneously talked about helplessness experiences, and to determine how helplessness is embedded in broader story lines. Three types of narrative composition were discerned, and are discussed by means of excerpts from the interviews. In a first and predominant type of narrative, a disturbing confrontation with another is pivotal: the other's intentions are obscure; this frightens the narrator, who does not know what to do. Helplessness arises as a direct result of not knowing how to manage the "unbearable riddle" of the other's intentions. In the second, more marginal type of narrative, helplessness is embedded in an account of emptiness and boredom. The protagonist relates enduring experiences of emptiness due to loss and the suffering consequent on it. In the third, also more marginal type of narrative, helplessness is framed in a context of failure: the protagonist adheres to strict standards, feels he or she has fallen short, and concludes that he or she is a failure. Only the first type of narrative is significantly related to the psychiatric diagnoses of mood disorder and major depression.

  18. Telerobotic Perception During Asteroid and Mars Regolith Operations Project

    Science.gov (United States)

    Gaddis, Steven; Zeitlin, Nancy (Compiler); Mueller, Robert (Compiler)

    2015-01-01

    Current space telerobotic systems are constrained to only operating in bright light and dust-free conditions. This project will study the effects of difficult lighting and dust conditions on telerobotic perception systems to better assess and refine regolith operations on other neighboring celestial bodies. In partnership with Embry-Riddle Aeronautical University and Caterpillar, Inc., optical, LiDAR and RADAR sensing equipment will be used in performing the study. This project will create a known dust environment in the Swamp Works Granular Mechanics & Regolith Operations (GMRO) Laboratory regolith test bin to characterize the behavior of the sensing equipment in various calibrated lighting and dust conditions. It will also identify potential methods for mitigating the impacts of these undesirable conditions on the performance of the sensing equipment. Enhancing the capability of telerobotic perception systems will help improve life on earth for those working in dangerous, dusty mining conditions, as well as help advance the same technologies used for safer self-driving automobiles in various lighting and weather conditions. It will also prove to be a critical skill needed for advancing robotic and human exploration throughout our solar system, for activities such as mining on an asteroid or pioneering the first colony on Mars.

  19. A perspective on emerging law, consumer trust and social responsibility in China's food sector: the "bleaching" case study.

    Science.gov (United States)

    Roberts, Michael T

    2011-01-01

    Trust underpins the Chinese social system, and yet it is lacking from a Chinese food system that is riddled with safety disasters and disgruntled consumers. Government and industry play a major role in rehabilitating consumer trust in China. To this end, food safety and quality laws have been constructed to foster this process; however, safety scandals continue even in the face of stricter regulations and increased enforcement. A potential toll to abate food-safety problems and to build trust is the implementation of Corporate Social Responsibility ("CSR"). Mandates by the government promote CSR in enterprise activity, including Article 3 of the 2009 China Food Safety Law. Officials have also recently touted the need for "moral education" of operators in the food industry. Regardless of government activity or whether CSR is employed by food enterprises, it is imperative that the food industry recognizes how critical it is to establish trust with Chinese consumers, who increasingly expect safe, quality food. The case study with pistachios highlights this evolving consumer expectation and the principles of social responsibility in the framework of the relationship between government and industry and consumers, while demonstrating the benefits of doing the right thing for food companies doing business in China.

  20. Hoarding behavior among young children with obsessive-compulsive disorder.

    Science.gov (United States)

    Frank, Hannah; Stewart, Elyse; Walther, Michael; Benito, Kristen; Freeman, Jennifer; Conelea, Christ; Garci, Abbe

    2014-01-01

    Previous research has shown that among the various subtypes of obsessive-compulsive disorder (OCD), adults (e.g. Frost, Krause & Steketee, 1996) and older children and adolescents (Bloch et al., 2009; Storch et al., 2007) with problematic hoarding have distinct features and a poor treatment prognosis. However, there is limited information on the phenomenology and prevalence of hoarding behaviors in young children. The present study characterizes children ages 10 and under who present with OCD and hoarding behaviors. Sixty-eight children received a structured interview-determined diagnosis of OCD. Clinician administered, parent-report, and child-report measures on demographic, symptomatic, and diagnostic variables were completed. Clinician ratings of hoarding symptoms and parent and child endorsement of the hoarding item on the CY-BOCS checklist (Scahill, Riddle, McSwiggin-Hardin, & Ort, 1997) determined inclusion in the hoarding group ( n =33). Compared to children without hoarding symptoms ( n =35), the presence of hoarding symptoms was associated with an earlier age of primary diagnosis onset and a higher proportion of ADHD and provisional anxiety diagnoses. These results are partially consistent with the adult literature and with findings in older children (Storch et al., 2007). Additional data on clinical presentation and phenomenology of hoarding are needed to form a developmentally appropriate definition of the behavior.

  1. Globalization and Religion in Historical Perspective: A Paradoxical Relationship

    Directory of Open Access Journals (Sweden)

    Luke M. Herrington

    2013-03-01

    Full Text Available Religion has long been a driving force in the process of globalization. This idea is not controversial or novel thinking, nor is it meant to be. However, the dominant reasoning on the subject of globalization, expressed by authors like Thomas Friedman, places economics at the center of analysis, skewing focus from the ideational factors at work in this process. By expanding the definition of globalization to accommodate ideational factors and cultural exchange, religion’s agency in the process can be enabled. Interestingly, the story of religion and globalization is in some ways the history of globalization, but it is riddled with paradoxes, including the agent-opponent paradox, the subject of this article. Religion and globalization have a co-constitutive relationship, but religious actors are both agents of globalization and principals in its backlash. While some actors might benefit from a mutually reinforcing relationship with globalization, others are marginalized in some way or another, so it is necessary to expose the links and wedges that allow for such a paradox. To that end, the concepts of globalization and religious actors must be defined, and the history of the agent-opponent paradox, from the Buddhists of the Silk Road to the Jubilee campaign of 2000, must be elucidated.

  2. Oedipus and the sphinx: triumph and catastrophe.

    Science.gov (United States)

    Palombo, S R

    1994-01-01

    The downfall of Oedipus in Sophocles' most famous play, Oedipus Tyrannus, is the reversal of his triumphant entry into the city of Thebes 17 years earlier. The oracle at Delphi has told the Thebans that the plague will end only when the murderer of Laius is identified and punished. The unconscious collusion between Oedipus and the Thebans to ignore the unsolved murder breaks down. Told by Teiresias that he is the culprit, Oedipus begins a desperate effort to find evidence to refute this accusation. When other witnesses come forward, his cause is lost. The effect of Oedipus's collusive interaction with the Thebans is balanced in Sophocles' account by the story of the riddle of the Sphinx. The Sphinx is a goddess of discontinuity. She represents the unconscious forces at work both in Oedipus's personal fantasies and in the collective fantasies of the Thebans. The tragedy results from the interaction of these fantasies in the government of the polis. Sophocles' play thus exemplifies the intricate intertwining of the child's innate wishes and the reaction they evoke from the environment during the oedipal period. The neurotic patient's illusion of sexual triumph over his or her father or mother as a child can be best understood through the interaction of these factors.

  3. Gatot Mangkupraja, PET A, and the origins of the Indonesian National Army

    Directory of Open Access Journals (Sweden)

    Shigeru Sato

    2010-09-01

    Full Text Available Indonesian nationalist Gatot Mangkupraja (1898-1968 was politically active throughout his adult life that extended over the turbulent periods called tiga jaman ('three eras' under the Dutch, the Japanese, and the Indonesian administration but he never reached real prominence, and is remembered primarily for his role in the formation of PETA (Pembela Tanah Air, Defenders of the Homeland. Gatot's fame rests on his own statement that he presented to the Japanese occupation authorities an impassioned petition written in his own blood pleading them to allow the Indonesians to form their own defence force. He made this statement in his memoirs, which were published in the journal Indonesia under the title: 'The PETA and My Relations with the Japanese; A Correction of Sukarno's Autobiography'. Some people cast doubt about the reliability of his statement, which resulted in heated debate in Indonesia in 1975. This debate however failed to clarify the issue in part because people’s access to source materials was limited at that time. Gatot's memoirs merit re-examination because they concern some key issues in modern Indonesian history and also because his memoirs, often cited uncritically, are, as this article will show, riddled with inaccuracies, both large and small.

  4. Does melanin matter in the dark?

    Science.gov (United States)

    Płonka, Przemysław M; Picardo, Mauro; Slominski, Andrzej T

    2017-07-01

    In living cells, melanin pigment is formed within melanosomes, which not only protect the cells from autodestruction, but also serve as second messenger organelles regulating important skin functions, with melanocytes acting as primary sensory and regulatory cells of the epidermis. Yet, one can argue that skin melanin, which may negatively affect cellular homeostasis in melanoma, really exerts protective functions. Consequently, the actual functions of melanin and the melanogenic pathway in skin biology remains enigmatic. Yet, the solution of this riddle seems simple - to check the actual influence of natural melanin on skin cells in the dark. Since many interesting hypotheses and theories put forward in this respect did not survive confrontation with the experiment, a leading pigment research group from Naples was brave to "jump off the cliff" by confronting theory with experimental reality. They showed that, in the dark, human hair-derived melanin promotes inflammatory responses in keratinocytes, lowers their viability, promotes oxidative stress, and that pheomelanin does so more strongly than eumelanin. Thus, pheomelanin hardly protects red-haired individuals, even when avoiding the sun. Black hairs do not do much better either, unless they undergo graying. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Probing Inflation via Cosmic Microwave Background Polarimetry

    Science.gov (United States)

    Chuss, David T.

    2008-01-01

    The Cosmic Microwave Background (CMB) has been a rich source of information about the early Universe. Detailed measurements of its spectrum and spatial distribution have helped solidify the Standard Model of Cosmology. However, many questions still remain. Standard Cosmology does not explain why the early Universe is geometrically flat, expanding, homogenous across the horizon, and riddled with a small anisotropy that provides the seed for structure formation. Inflation has been proposed as a mechanism that naturally solves these problems. In addition to solving these problems, inflation is expected to produce a spectrum of gravitational waves that will create a particular polarization pattern on the CMB. Detection of this polarized signal is a key test of inflation and will give a direct measurement of the energy scale at which inflation takes place. This polarized signature of inflation is expected to be -9 orders of magnitude below the 2.7 K monopole level of the CMB. This measurement will require good control of systematic errors, an array of many detectors having the requisite sensitivity, and a reliable method for removing polarized foregrounds, and nearly complete sky coverage. Ultimately, this measurement is likely to require a space mission. To this effect, technology and mission concept development are currently underway.

  6. Structural Testing of the Blade Reliability Collaborative Effect of Defect Wind Turbine Blades

    Energy Technology Data Exchange (ETDEWEB)

    Desmond, M. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hughes, S. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Paquette, J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-06-08

    Two 8.3-meter (m) wind turbine blades intentionally constructed with manufacturing flaws were tested to failure at the National Wind Technology Center (NWTC) at the National Renewable Energy Laboratory (NREL) south of Boulder, Colorado. Two blades were tested; one blade was manufactured with a fiberglass spar cap and the second blade was manufactured with a carbon fiber spar cap. Test loading primarily consisted of flap fatigue loading of the blades, with one quasi-static ultimate load case applied to the carbon fiber spar cap blade. Results of the test program were intended to provide the full-scale test data needed for validation of model and coupon test results of the effect of defects in wind turbine blade composite materials. Testing was part of the Blade Reliability Collaborative (BRC) led by Sandia National Laboratories (SNL). The BRC seeks to develop a deeper understanding of the causes of unexpected blade failures (Paquette 2012), and to develop methods to enable blades to survive to their expected operational lifetime. Recent work in the BRC includes examining and characterizing flaws and defects known to exist in wind turbine blades from manufacturing processes (Riddle et al. 2011). Recent results from reliability databases show that wind turbine rotor blades continue to be a leading contributor to turbine downtime (Paquette 2012).

  7. Review Essay: A Nation, a World, in a Bowl of Tea

    Directory of Open Access Journals (Sweden)

    Dana Buntrock

    2013-06-01

    Full Text Available Fujimori Terunobu. 藤森照信. Fujimori Terunobu no Chashitsugaku: Nihon no Kyokushō Kūkan no Nazo [Fujimori Terunobu’s tearoom studies: The riddle of Japan’s smallest space]. 藤森照信の茶室学。日本の極小空間の謎. Tokyo: Rikuyosha, 2012. 296 pp. ¥3,000 (cloth.Surak, Kristin. Making Tea, Making Japan: Cultural Nationalism in Practice. Stanford, CA: Stanford University Press, 2012. 272 pp. $85 (cloth, $25 (paper/ebook.The tea in Surak’s bowl is bright green matcha whipped with a whisk; Fujimori’s is steeped sencha heated over a tiny bed of coals. Fujimori’s funky tea seems to be the antithesis of the refined practices Surak strives to embody. Only occasionally does a communicant in Fujimori’s tea space wear a kimono, and there is no reason to worry about treading on the silk borders of a tatami, because his floors are usually finished in other, more modest, materials. Fujimori’s tea is one that can accept outside influences; Surak’s sits complacently at the center of an industry built on centuries of history. Surak shares the conventions of tea; Fujimori celebrates its unconventional fringes.

  8. Transformation priming helps to disambiguate sudden changes of sensory inputs.

    Science.gov (United States)

    Pastukhov, Alexander; Vivian-Griffiths, Solveiga; Braun, Jochen

    2015-11-01

    Retinal input is riddled with abrupt transients due to self-motion, changes in illumination, object-motion, etc. Our visual system must correctly interpret each of these changes to keep visual perception consistent and sensitive. This poses an enormous challenge, as many transients are highly ambiguous in that they are consistent with many alternative physical transformations. Here we investigated inter-trial effects in three situations with sudden and ambiguous transients, each presenting two alternative appearances (rotation-reversing structure-from-motion, polarity-reversing shape-from-shading, and streaming-bouncing object collisions). In every situation, we observed priming of transformations as the outcome perceived in earlier trials tended to repeat in subsequent trials and this repetition was contingent on perceptual experience. The observed priming was specific to transformations and did not originate in priming of perceptual states preceding a transient. Moreover, transformation priming was independent of attention and specific to low level stimulus attributes. In summary, we show how "transformation priors" and experience-driven updating of such priors helps to disambiguate sudden changes of sensory inputs. We discuss how dynamic transformation priors can be instantiated as "transition energies" in an "energy landscape" model of the visual perception. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Issues in identifying germ tube positive yeasts by conventional methods.

    Science.gov (United States)

    Yazdanpanah, Atta; Khaithir, Tzar Mohd Nizam

    2014-01-01

    Candida speciation is vital for epidemiology and management of candidiasis. Nonmolecular conventional methods often fail to identify closely related germ tube positive yeasts from clinical specimens. The present study was conducted to identify these yeasts and to highlight issues in conventional versus molecular methods of identification. A total of 98 germ tube positive yeasts from high vaginal swabs were studied over a 12-month period. Isolates were examined with various methods including growth at 42 °C and 45 °C on Sabouraud dextrose agar (SDA), color development on CHROMagar Candida medium, chlamydospore production on corn meal agar at 25 °C, carbohydrate assimilation using ID 32C system, and polymerase chain reaction using a single pair of primers targeting the hyphal wall protein 1 (Hwp1) gene. Of all the isolates studied, 97 were molecularly confirmed as C. albicans and one isolate was identified as C. dubliniensis. No C. africana was detected in this study. The molecular method used in our study was an accurate and useful tool for discriminating C. albicans, C. dubliniensis, and C. africana. The conventional methods, however, were less accurate and riddled with many issues that will be discussed in further details. © 2013 Wiley Periodicals, Inc.

  10. SecureCPS: Defending a nanosatellite cyber-physical system

    Science.gov (United States)

    Forbes, Lance; Vu, Huy; Udrea, Bogdan; Hagar, Hamilton; Koutsoukos, Xenofon D.; Yampolskiy, Mark

    2014-06-01

    Recent inexpensive nanosatellite designs employ maneuvering thrusters, much as large satellites have done for decades. However, because a maneuvering nanosatellite can threaten HVAs on-­orbit, it must provide a level of security typically reserved for HVAs. Securing nanosatellites with maneuvering capability is challenging due to extreme cost, size, and power constraints. While still in the design process, our low-­cost SecureCPS architecture promises to dramatically improve security, to include preempting unknown binaries and detecting abnormal behavior. SecureCPS also applies to a broad class of cyber-­physical systems (CPS), such as aircraft, cars, and trains. This paper focuses on Embry-­Riddle's ARAPAIMA nanosatellite architecture, where we assume any off-­the-­shelf component could be compromised by a supply chain attack.1 Based on these assumptions, we have used Vanderbilt's Cyber Physical -­ Attack Description Language (CP-­ADL) to represent realistic attacks, analyze how these attacks propagate in the ARAPAIMA architecture, and how to defeat them using the combination of a low-­cost Root of Trust (RoT) Module, Global InfoTek's Advanced Malware Analysis System (GAMAS), and Anomaly Detection by Machine Learning (ADML).2 Our most recent efforts focus on refining and validating the design of SecureCPS.

  11. Baseline metal concentrations in Paramoera walkeri from East Antarctica

    International Nuclear Information System (INIS)

    Palmer, Anne S. . E-mail Anne.Palmer@utas.edu.au; Snape, Ian; Stark, Jonathan S.; Johnstone, Glenn J.; Townsend, Ashley T.

    2006-01-01

    Remediation of the Thala Valley waste disposal site near Casey Station, East Antarctica was conducted in the austral summer of 2003/2004. Biomonitoring of the adjacent marine environment was undertaken using the gammaridean amphipod Paramoera walkeri as a sentinel species [Stark, J.S., Johnstone, G.J., Palmer, A.S., Snape, I., Larner, B.L., Riddle, M.J., in press, doi:10.1016/j.marpolbul.2006.05.020. Monitoring the remediation of a near shore waste disposal site in Antarctica using the amphipod Paramoera walkeri and diffusive gradients in thin films (DGTs). Marine Pollution Bulletin and references therein]. Determination of uptake of metals and hypothesis testing for differences that could be attributed to contamination required the establishment of baseline metal concentrations in P. walkeri. Baseline metal concentrations from two reference locations in the Windmill Islands are presented here. P. walkeri was a found to be a sensitive bioaccumulating organism that recorded spatial and temporal variability at the reference sites. Measurement of metals in P. walkeri required the development of a simple digestion procedure that used concentrated nitric acid. For the first time, rare earth metals were determined with additional clean procedures required to measure ultra low concentrations using magnetic sector ICP-MS. Certified and in-house reference materials were employed to ensure method reliability

  12. [Skills Training for Patients with Borderline Personality Disorder].

    Science.gov (United States)

    Armbrust, Michael; Ehrig, Christian

    2016-07-01

    The emotionally instable personality disorder, mostly called borderline disorder, shows central abnormalities in impulse control as well as instability of mood and identity. It is composed of behaviour problems in creating relationships and in self-management, first of all by high psychophysiological tension. The prevalence of this disorder is 10 % in outpatients and 20 % in inpatients and has therefore high relevance for the medical-psychotherapeutic care system. The treatment is deemed to be complex and interminable. Regarding all evaluated techniques of treatment the best examined is the Dialectical Behavioral Therapy (DBT). This specific therapy, developed in the eighties by Marsha M. Linehan, can be used for inpatient and outpatient treatment and combines single and group sessions. It is essential in mental health care of this disorder, but not available everywhere. Essential part of DBT is the skill training, a specific technique for the acquirement and for exercising skills for mindfulness, modulation of tension, regulation of emotions, structuring of social competence and developing self value. The central goal of DBT is to ensure the survival of the patients, to reduce self- and external aggressive behaviour and to provide inpatient crisis interventions. For sustained crisis management skills for reality acceptance are best fitting. But before, fast available sensory and active body-related skills should be used. Radical acceptance is the most important, since most effective, skill. The skills training, although in use for only twenty years, is permanently expanding in practice and is meanwhile also used for other disorders such as, for example, PTSD or ADHD. Since 2010, there also exists an elaborated DBT-version for adolescents. For medical care politics and health-economic reasons a supply with skills training for in- and outpatients all over the country is desirable. © Georg Thieme Verlag KG Stuttgart · New York.

  13. Understanding kangaroo care and its benefits to preterm infants

    Directory of Open Access Journals (Sweden)

    Campbell-Yeo ML

    2015-03-01

    Full Text Available Marsha L Campbell-Yeo,1–4 Timothy C Disher,1 Britney L Benoit,1 C Celeste Johnston,2,4,5 1School of Nursing, Dalhousie University, 2Department of Pediatrics, IWK Health Centre, 3Department of Psychology and Neuroscience, Dalhousie University, 4Centre for Pediatric Pain Research, IWK Health Centre, Halifax, NS, 5Ingram School of Nursing, McGill University, Montréal, QC, Canada Abstract: The holding of an infant with ventral skin-to-skin contact typically in an upright position with the swaddled infant on the chest of the parent, is commonly referred to as kangaroo care (KC, due to its simulation of marsupial care. It is recommended that KC, as a feasible, natural, and cost-effective intervention, should be standard of care in the delivery of quality health care for all infants, regardless of geographic location or economic status. Numerous benefits of its use have been reported related to mortality, physiological (thermoregulation, cardiorespiratory stability, behavioral (sleep, breastfeeding duration, and degree of exclusivity domains, as an effective therapy to relieve procedural pain, and improved neurodevelopment. Yet despite these recommendations and a lack of negative research findings, adoption of KC as a routine clinical practice remains variable and underutilized. Furthermore, uncertainty remains as to whether continuous KC should be recommended in all settings or if there is a critical period of initiation, dose, or duration that is optimal. This review synthesizes current knowledge about the benefits of KC for infants born preterm, highlighting differences and similarities across low and higher resource countries and in a non-pain and pain context. Additionally, implementation considerations and unanswered questions for future research are addressed. Keywords: kangaroo care, skin-to-skin contact, infant, preterm, review

  14. Adaptive Noise Suppression of Pediatric Lung Auscultations With Real Applications to Noisy Clinical Settings in Developing Countries

    Science.gov (United States)

    Emmanouilidou, Dimitra; McCollum, Eric D.; Park, Daniel E.

    2015-01-01

    Goal Chest auscultation constitutes a portable low-cost tool widely used for respiratory disease detection. Though it offers a powerful means of pulmonary examination, it remains riddled with a number of issues that limit its diagnostic capability. Particularly, patient agitation (especially in children), background chatter, and other environmental noises often contaminate the auscultation, hence affecting the clarity of the lung sound itself. This paper proposes an automated multiband denoising scheme for improving the quality of auscultation signals against heavy background contaminations. Methods The algorithm works on a simple two-microphone setup, dynamically adapts to the background noise and suppresses contaminations while successfully preserving the lung sound content. The proposed scheme is refined to offset maximal noise suppression against maintaining the integrity of the lung signal, particularly its unknown adventitious components that provide the most informative diagnostic value during lung pathology. Results The algorithm is applied to digital recordings obtained in the field in a busy clinic in West Africa and evaluated using objective signal fidelity measures and perceptual listening tests performed by a panel of licensed physicians. A strong preference of the enhanced sounds is revealed. Significance The strengths and benefits of the proposed method lie in the simple automated setup and its adaptive nature, both fundamental conditions for everyday clinical applicability. It can be simply extended to a real-time implementation, and integrated with lung sound acquisition protocols. PMID:25879837

  15. Search for low energy quasi-vertical muons with an underwater cosmic neutrino detector, environmental study of the detector setting; Recherche de muons quasi verticaux de basse energie a l'aide d'un detecteur de neutrinos cosmiques sous-marin et etude environnementale de son site d'installation

    Energy Technology Data Exchange (ETDEWEB)

    Blondeau, F. [CEA/Saclay, Dept. d' Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l' Instrumentation Associee (DAPNIA), 91 - Gif-sur-Yvette (France)]|[Paris-7 Univ., 75 (France)

    1999-06-01

    The European collaboration named ANTARES aims at operating a large submarine neutrino telescope. Mooring lines make up this detector. Each is about four hundred metres high and equipped with photomultiplier tubes. These tubes record the Cherenkov light emitted by muons resulting from the interaction of neutrinos with matter. It was chosen to install the telescope in the Mediterranean, off the shore of Toulon, by a depth of twenty-three hundred metres. One chapter of this dissertation is devoted to the environment parameters of this site: amount of natural light, fouling of glass elements and water transparency is reviewed. Such a disposal is originally designed to look for possible astronomic neutrino sources emitting neutrinos, thus being complementary with the study of our Universe relying on gamma rays. It is shown in this dissertation that two other current riddles in physics can be investigated by ANTARES, when a specific analysis is taken into account: what is the mass of the neutrinos on the one hand (via the phenomenon called neutrino oscillations), and in the other hand the evidence for a new particle which could participate to the nature of the dark matter in the Universe. This analysis is based upon the detection of nearly vertical muons (zenith angle less than fifteen degrees), with an energy lower than 100 GeV. (author)

  16. Parallels and contrasts - Wendezeit in South African and German literature

    Directory of Open Access Journals (Sweden)

    P. Horn

    1997-04-01

    Full Text Available We live in the present, but our language is always the language of the past. Memory is fragile, evanescent and often distorted. Even where memories are vivid and subjectively compelling, there is no guarantee that they are correct. The documents which come down to us are riddled with lacunae, silences, and with outright lies. But these documents are the basis and the limit of our constant rewriting of history. Official history is an erasure of an alternative history. The truth, which surfaces in myths and stories, is the truth forgotten by history, or more precisely, the truth repressed by history. Not only the henchmen and the prison warders have a bad memory. The victims, too, have difficulties remembering. But not to want to know the truth about oneself is an attitude which always leads to catastrophe. Literature discovers the dark underworld beneath the glittering surface of this country, which considers itself to be happy. It is art, the novel, the poem, the image, which transcends the boundary of that area which is excluded from language. Fictional reports can, however, do that only because they lack the authority of official history writing, because that which is written fictionally has been called a lie since the time of Plato. There is, nevertheless, a silence underneath the rationality of the historical method, an unknown.

  17. An Investigation of Primary School Teachers’ PCK towards Science Subjects Using an Inquiry-Based Approach

    Directory of Open Access Journals (Sweden)

    Menşure ALKIŞ KÜÇÜKAYDIN

    2016-09-01

    Full Text Available In this study, the pedagogical content knowledge (PCK of four experienced primary school teachers was investigated within the “Let’s Solve the Riddle of Our Body Unit”. The PCK investigation adopted a learning approach based on inquiry, content representation and pedagogical and professional-experience repertoires (PaP-eRs, and interview forms were used as data collection tools. During the course of the research, the findings obtained from observations made during a total of 18 course hours formed the basic data source of the study. According to the results of the study, in which descriptive and content analysis were used concurrently, primary school teachers lack subject matter knowledge, do not interrogate the pre-knowledge of students and some misconceptions exist regarding about blood moves and exercise with pulse. Additionally, some deficiencies were detected in the curriculum, i.e., it offers non-inquisitional knowledge. Furthermore, teachers employee assessment methods with traditional teaching methods and techniques. In the context of an inquiry-based learning approach, teachers appeared to believe that classroom activities were adversely affected by the physical conditions (class size, lack of laboratory etc., students’ cognitive levels and parent profiles. The result of this study revealed that PCK components affect one another. The PCK findings pertaining to primary school teachers as it concerns the unit are briefly discussed and some suggestions about the development of PCK are submitted.

  18. An investigation of primary school teachers’ PCK towards science subjects using an ınquiry-based approach

    Directory of Open Access Journals (Sweden)

    Menşure Alkış Küçükaydın

    2016-09-01

    Full Text Available In this study, the pedagogical content knowledge (PCK of four experienced primary school teachers was investigated within the “Let’s Solve the Riddle of Our Body Unit”. The PCK investigation adopted a learning approach based on inquiry, content representation and pedagogical and professional-experience repertoires (PaP-eRs, and interview forms were used as data collection tools. During the course of the research, the findings obtained from observations made during a total of 18 course hours formed the basic data source of the study. According to the results of the study, in which descriptive and content analysis were used concurrently, primary school teachers lack subject matter knowledge, do not interrogate the pre-knowledge of students and some misconceptions exist regarding about blood moves and exercise with pulse. Additionally, some deficiencies were detected in the curriculum, i.e., it offers non-inquisitional knowledge. Furthermore, teachers employee assessment methods with traditional teaching methods and techniques. In the context of an inquiry-based learning approach, teachers appeared to believe that classroom activities were adversely affected by the physical conditions (class size, lack of laboratory etc., students’ cognitive levels and parent profiles. The result of this study revealed that PCK components affect one another. The PCK findings pertaining to primary school teachers as it concerns the unit are briefly discussed and some suggestions about the development of PCK are submitted.

  19. Equilibrium Figures inside the Dark-Matter Ring and the Shapes of Elliptical Galaxies

    Directory of Open Access Journals (Sweden)

    Kondratyev B. P.

    2015-12-01

    Full Text Available We solve the general problem of the theory of equilibrium figures and analyze two classes of liquid rotating gravitating figures residing inside a gravitating ring or torus. These figures form families of sequences of generalized oblate spheroids and triaxial ellipsoids, which at the lower limit of the tidal parameter α = 0 have the form of the Maclaurin spheroids and the Jacobi ellipsoids. In intermediate cases 0 < α ≤ αmax each new sequence of axisymmetric equilibrium figures has two non-rotating boundary spheroids. At the upper limit αmax/(πGρ = 0.1867 the sequence degenerates into a single non-rotating spheroid with the eccentricity ecr ≈ 0.96 corresponding to the flattening limit of elliptical galaxies (E7. We also perform a detailed study of the sequences of generalized triaxial ellipsoids and find bifurcation points of triaxial ellipsoids in the sequences of generalized spheroids. We use this method to explain the shapes of E-galaxies. According to observations, very slowly rotating oblate E-type galaxies are known that have the shapes, which, because of instability, cannot be supported by velocity dispersion anisotropy exclusively. The hypothesis of a massive dark-matter outer ring requires no extreme anisotropy of pressure; it not only explains the shape of these elliptical galaxies, but also sheds new light on the riddle of the ellipticity limit (E7 of elliptical galaxies.

  20. Palm fruit in traditional African food culture.

    Science.gov (United States)

    Atinmo, Tola; Bakre, Aishat Taiwo

    2003-01-01

    The centre of origin of the oil palm is the tropical rain forest region of West Africa. It is considered to be the 200-300 kilometre wide coastal belt between Liberia and Mayumbe. The oil palm tree has remained the 'tree of life' of Yoruba land as well as of other parts of southern West Africa to which it is indigenous. The Yoruba are adept at spinning philosophical and poetical proverbs around such ordinary things as hills, rivers, birds, animals and domestic tools. Hundreds of the traditional proverbs are still with us, and through them one can see the picture of the environment that contributed to the moulding of the thoughts of the people. Yoruba riddles or puzzles were also couched in terms of the environment and the solutions to them were also environmental items. They have a popular saying: A je eran je eran a kan egungun, a je egungun je egungun a tun kan eran: 'A piece of meat has an outer layer of flesh, an intermediate layer of bone and an inner layer of flesh'. What is it? A palm fruit: it has an outer edible layer, the mesocarp; then a layer of shell, inedible, and the kernel inside, edible. The solution to this puzzle summarises the botanical and cultural characteristics of the palm fruit.

  1. Design, fabrication, and characterization of a 2.3 kJ plasma focus of negative inner electrode

    International Nuclear Information System (INIS)

    Mathuthu, M.; Zengeni, T.G.; Gholap, A.V.

    1997-01-01

    The design, fabrication, and characterization of a 2.3 kJ plasma focus device with negative inner electrode are discussed. The purpose of the design was to initiate research in and study of plasma dynamics, nuclear reactions, and neutron emission mechanisms at the university. Also the device will be used to teach and demonstrate plasma phenomena at the postgraduate level and to perform experiments with inverted polarity to examine different operating regimes with nonstandard gases. It is hoped that in the long run the research work will help find a solution to the polarity riddle of plasma focus devices. When the system was operated with spectrographic argon as the filling gas, the best focus was obtained at a pressure range of 0.1 endash 1.25 Torr. With nitrogen as the filling gas, the best focus was obtained at pressures between 0.1 and 1.25 Torr. Air gave the best focus at a pressure range of 0.5 endash 1.5 Torr. The observed good focus action is attributed to the small inner electrode length (this reduces the amount of anode material ablated into the current sheath) and tapering of the inner electrode. Positive z-directed electrons contribute to the temperature and further ionization of the plasma gas during focusing. The performance of the device compares quite well with other known devices. copyright 1997 American Institute of Physics

  2. Cheat Electricity? The Political Economy of Green Electricity Delivery on the Dutch Market for Households and Small Business

    Directory of Open Access Journals (Sweden)

    J. A. M. Hufen

    2016-12-01

    Full Text Available The European Commission’s renewable energy directive introduced a market-based Guarantees of Origin (GO-trade system that gives consumers the choice of buying “real” green energy. This has been successful, as the market share of Dutch households that buy green energy grew to 64% in 2015. However, societal organizations are dissatisfied with the green energy offered, categorizing it as “cheat” electricity. This article aims to solve this riddle of a successful product created under the GO-trade system but also heavily criticized. Research reveals a lively marketplace with buyers eager to buy green energy and energy producers offering a wide range of labels. Marketplace mechanisms are strongly influenced by political choices, and financial support for energy suppliers makes green energy a credible option. Societal groups, however, argue that the information provided is incomplete and misleading, that buying green energy does not impact positively on greenhouse gas reduction, and that better information and structural reform are required. The GO-trade system is strongly influenced by member states’ national energy politics. Societal organizations have helped to optimize the implementation of the GO-trade system in the Netherlands, but they are not expected to be able to support the creation of a level playing field in which an optimal GO-trade system will flourish.

  3. Nabokov's Amphiphorical Gestures

    Directory of Open Access Journals (Sweden)

    S. E. Sweeney

    1987-01-01

    Full Text Available In addition to using two primary kinds of metaphors (those that clarify descriptions, and those that develop into leitmotifs, Nabokov's fiction demonstrates a third kind that is characterized by extended analogies, baroque, seemingly uncontrolled imagery and rhetoric, and, most importantly, fundamental ambiguity. Although this inherent ambiguity is developed throughout the comparison, it is never resolved. Because of this distinguishing characteristic, I have named such metaphors "amphiphors," after one of Nabokov's own neologisms. Nabokov's comments in Nikolai Gogol and Lectures on Russian Literature , as well as direct allusions to Gogol embedded in a few amphiphors, suggest that this device evolved directly from Gogol's absurd, overgrown images and Protean minor characterizations. Yet, whereas Gogol's "spontaneous generation" is careless, uncontrolled, and comical, Nabokov uses his amphiphors deliberately for ironic effect. More precisely, he exploits the gap between the initial and final points of the comparison to create a sustained and irreconcilable ambiguity—what William Empson called the seventh type, "at once an indecision and a structure." Moreover, close textual analysis of the mechanics of several amphiphors, from Speak, Memory and Bend Sinister , shows marked similarities in content and authorial intention. In each instance, Nabokov uses the amphiphor's inherent stylistic ambiguity to delineate a similar phenomenological one: his own ambivalence towards death (whether his own, his father's, or his hero's and the insolubility of its "monstrous riddle."

  4. Equilibrium figures inside the dark-matter ring and the shapes of elliptical galaxies

    Science.gov (United States)

    Kondratyev, B. P.; Trubitsyna, N. G.; Kireeva, E. N.

    We solve the general problem of the theory of equilibrium figures and analyze two classes of liquid rotating gravitating figures residing inside a gravitating ring or torus. These figures form families of sequences of generalized oblate spheroids and triaxial ellipsoids, which at the lower limit of the tidal parameter α = 0 have the form of the Maclaurin spheroids and the Jacobi ellipsoids. In intermediate cases 0 equilibrium figures has two non-rotating boundary spheroids. At the upper limit αmax/(π Gρ ) = 0.1867 the sequence degenerates into a single non-rotating spheroid with the eccentricity {e cr} ≈ 0.96 corresponding to the flattening limit of elliptical galaxies (E7). We also perform a detailed study of the sequences of generalized triaxial ellipsoids and find bifurcation points of triaxial ellipsoids in the sequences of generalized spheroids. We use this method to explain the shapes of E-galaxies. According to observations, very slowly rotating oblate E-type galaxies are known that have the shapes, which, because of instability, cannot be supported by velocity dispersion anisotropy exclusively. The hypothesis of a massive dark-matter outer ring requires no extreme anisotropy of pressure; it not only explains the shape of these elliptical galaxies, but also sheds new light on the riddle of the ellipticity limit (E7) of elliptical galaxies.

  5. Proverbs 30:18-19 in the Light of Ancient Mesopotamian Cuneiform Texts

    Directory of Open Access Journals (Sweden)

    Böck, Barbara

    2009-12-01

    Full Text Available The meaning of Proverbs 30:18-19 has long been disputed. Most scholars interpret the Biblical couplets textually on stylistic features only; an explanation of the contextual association between the four motifs mentioned (eagle, serpent, boat, man and woman has not yet been undertaken. The present paper aims at shedding light on the motivation for this association, taking into consideration ancient Near Eastern cuneiform compositions for the first time. It is further suggested that Proverbs 30:18-19 derived originally from a riddle that had its setting in a wedding ceremony.El significado de Proverbios 30:18-19 sigue desafiando la exégesis de los biblistas. La mayoría de los comentaristas interpretan los versos bíblicos textualmente, ciñéndose al análisis de las figuras de estilo. Sin embargo, todavía no se ha dado ninguna explicación a la asociación contextual entre los cuatro motivos del proverbio (águila, serpiente, barco, hombre y mujer. Por primera vez, este artículo estudia composiciones de la literatura cuneiforme que ofrecen un telón de fondo para interpretar el sentido de los distintos elementos y del conjunto del proverbio bíblico. Según esta nueva lectura, Proverbios 30:18-19 describiría una adivinanza propuesta durante una ceremonia matrimonial.

  6. Learning from evolutionary optimisation: what are toughening mechanisms good for in dentine, a nonrepairing bone tissue?

    Science.gov (United States)

    Zaslansky, Paul; Currey, John D; Fleck, Claudia

    2016-09-12

    The main mass of material found in teeth is dentine, a bone-like tissue, riddled with micron-sized tubules and devoid of living cells. It provides support to the outer wear-resistant layer of enamel, and exhibits toughening mechanisms which contribute to crack resistance. And yet unlike most bone tissues, dentine does not remodel and consequently any accumulated damage does not 'self repair'. Because damage containment followed by tissue replacement is a prime reason for the crack-arresting microstructures found in most bones, the occurrence of toughening mechanisms without the biological capability to repair is puzzling. Here we consider the notion that dentine might be overdesigned for strength, because it has to compensate for the lack of cell-mediated healing mechanisms. Based on our own and on literature-reported observations, including quasistatic and fatigue properties, dentine design principles are discussed in light of the functional conditions under which teeth evolved. We conclude that dentine is only slightly overdesigned for everyday cyclic loading because usual mastication stresses may come close to its endurance strength. The in-built toughening mechanisms constitute an evolutionary benefit because they prevent catastrophic failure during rare overload events, which was probably very advantageous in our hunter gatherer ancestor times. From a bio-inspired perspective, understanding the extent of evolutionary overdesign might be useful for optimising biomimetic structures used for load bearing.

  7. Synthesis of OMS Materials and Investigation of Their Acceptor-Donor Characteristics.

    Science.gov (United States)

    Grajek, H; Paciura-Zadrożna, J; Choma, J; Michalski, E; Witkiewicz, Z

    2012-10-01

    Three ordered mesoporous siliceous (OMS) materials known as MCM41s-unmodified MCM-41C16 ("C16"), and two MCM41s with different surface functionalities: MCM-41C16-SH ("C16-SH") and MCM-41C16-NH 2 ("C16-NH 2 ")-were synthesized and studied by inverse gas chromatography in order to determine their acceptor-donor properties. The specific retention volumes of nonpolar and polar probes that were chromatographed on these ordered mesoporous silica adsorbents were evaluated under infinite dilution conditions. Two methods were employed to calculate the standard free energy of adsorption, Δ G ads , of each chromatographed probe on the basis its specific retention volume. These Δ G ads values were then employed to estimate the van der Waals contribution and the specific contribution of the free surface energy for each MCM41. DN values (donor numbers, based on the Gutmann scale) and AN* values (acceptor numbers, based on the Riddle-Fowkes scale) were employed to determine the values of parameters that characterize the ability of the MCM41s to act as electron acceptors (parameter: K A ) and donors (parameter: K D ). Considering the different compositions of the probes, each of which has different acceptor-donor properties, a new chromatographic test to supplement the Grob test is suggested.

  8. Search for low energy quasi-vertical muons with an underwater cosmic neutrino detector, environmental study of the detector setting

    International Nuclear Information System (INIS)

    Blondeau, F.

    1999-06-01

    The European collaboration named ANTARES aims at operating a large submarine neutrino telescope. Mooring lines make up this detector. Each is about four hundred metres high and equipped with photomultiplier tubes. These tubes record the Cherenkov light emitted by muons resulting from the interaction of neutrinos with matter. It was chosen to install the telescope in the Mediterranean, off the shore of Toulon, by a depth of twenty-three hundred metres. One chapter of this dissertation is devoted to the environment parameters of this site: amount of natural light, fouling of glass elements and water transparency is reviewed. Such a disposal is originally designed to look for possible astronomic neutrino sources emitting neutrinos, thus being complementary with the study of our Universe relying on gamma rays. It is shown in this dissertation that two other current riddles in physics can be investigated by ANTARES, when a specific analysis is taken into account: what is the mass of the neutrinos on the one hand (via the phenomenon called neutrino oscillations), and in the other hand the evidence for a new particle which could participate to the nature of the dark matter in the Universe. This analysis is based upon the detection of nearly vertical muons (zenith angle less than fifteen degrees), with an energy lower than 100 GeV. (author)

  9. Search for low energy quasi-vertical muons with an underwater cosmic neutrino detector, environmental study of the detector setting; Recherche de muons quasi verticaux de basse energie a l'aide d'un detecteur de neutrinos cosmiques sous-marin et etude environnementale de son site d'installation

    Energy Technology Data Exchange (ETDEWEB)

    Blondeau, F [CEA/Saclay, Dept. d' Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l' Instrumentation Associee (DAPNIA), 91 - Gif-sur-Yvette (France); [Paris-7 Univ., 75 (France)

    1999-06-01

    The European collaboration named ANTARES aims at operating a large submarine neutrino telescope. Mooring lines make up this detector. Each is about four hundred metres high and equipped with photomultiplier tubes. These tubes record the Cherenkov light emitted by muons resulting from the interaction of neutrinos with matter. It was chosen to install the telescope in the Mediterranean, off the shore of Toulon, by a depth of twenty-three hundred metres. One chapter of this dissertation is devoted to the environment parameters of this site: amount of natural light, fouling of glass elements and water transparency is reviewed. Such a disposal is originally designed to look for possible astronomic neutrino sources emitting neutrinos, thus being complementary with the study of our Universe relying on gamma rays. It is shown in this dissertation that two other current riddles in physics can be investigated by ANTARES, when a specific analysis is taken into account: what is the mass of the neutrinos on the one hand (via the phenomenon called neutrino oscillations), and in the other hand the evidence for a new particle which could participate to the nature of the dark matter in the Universe. This analysis is based upon the detection of nearly vertical muons (zenith angle less than fifteen degrees), with an energy lower than 100 GeV. (author)

  10. Bachelard et la psychanalyse de la “matière noire”

    Directory of Open Access Journals (Sweden)

    Vincent Bontems

    2012-10-01

    Full Text Available On several occasions, Gaston Bachelard has suggested that his poetic of elements could be extended beyond the four chemical elements, notably by increasing the specificity of the material imagination related to darkness, to the nocturne element, to the material called “la ténèbre” (the darkness. According to this thinking, we propose a dual examination of some physical concepts which include the adjective "black(/dark": the black bodies, the black holes, and the dark matters. To understand the nature of these dark thoughts, it is necessary to explain the process by which the physical transforms the meaning of the adjective, but also five free rein to a poetic digression that reveals how the dark "colours" concepts by associating them with other images. The riddle of the black body radiation is no longer simply the opportunity to explore the quantum but also the pattern of a self-awareness rêverie; the black hole is not only a singularity of the theory of general relativity but also a symbol of great depression; the dark matter is no longer just an astrophysics hypothesis but also the object of a fantasized alchemical research. Combining psychoanalysis and epistemology of knowledge about the physical "black" we hope to show how the duality of Bachelard’s philosophy responds to the provocations of material to think and dream.

  11. Myxomycetes do Canavial I: levantamento florístico em Carpina - Pernambuco Myxomycetes of sugar-cane plantation I: foristic survey in Carpina - Pernambuco state

    Directory of Open Access Journals (Sweden)

    Eneida Jucene dos Santos

    1991-07-01

    Full Text Available Durante um ano investigou-se a ocorrência, freqüência e constância de Myxomycetes em um canavial da Estação Experimental do PLANALSUCAR, em Carpina-PE. As observações foram efetuadas nos meses de março, junho, setembro e dezembro, correspondentes a diferentes etapas do cultivo da cana-de-açúcar. Numa área de 1.134m2, observou-se um total de 40 touceiras, em cada mês de coletas, examinando-se folhas, colmos e raízes (vivos ou mortos, bem como a superfície do solo. Foram registradas oito espécies, todas pertencentes à subclasse Myxogastromycetidae: Cribraria splendens (Schr. Pers. (Liceales; Arcyria cinerea (Buli. Pers., A. deruidata (L. Wett. e Trichia favoginea (Batsch. Pers. (Trichiales; Craterirum leucocephalum (Pers. Ditmar, Physarumnucleatum Ré x, P. nutans Pers. e P. cf. pezizoideum (Jung. Pav. & Lag. (Physarales. No levantamento efetuado, a espécie mais freqüente foi C. leucocephalum (70,4%, as demais sendo de ocorrência rara (7,4 - 3,7%. Nenhuma espécie foi classificada como constante no canavial; C. leucocephalum foi registrada como acessória e as outras espécies como acidentais.Myxomycetes from sugar-cane plantation I - Floristic Survey. Occurrence, frequence and constancy of Myxomycetes has been investigated on a sugar-cane plantation of the Experimental Station PLANALSUCAR, in Carpina, Pernambuco. The observations were carried out in March, June, September and December corresponding to differents stages of sugar-cane culture. Within an area of 1134m²/40 individuals were sampred at each month of collection. Their leaves, stems and roots (alive or dead as well as soil surface were all examined. Eight species were recorded, all belonging to the subclass Myxogastromycetidae: Cribraria splendens (Schr. Pers. (Liceales; Arcyriacinerea (Bull. Pers., A. denudata (L. Wett, and Tricchia favoginea (Batsch. Pers. (Trichiales; Craterium leucocephalum (Pers. Ditmar, Physarum nucleatum Rex, P. nutans Pers. and. P. cf

  12. Cardiology update 2016

    Directory of Open Access Journals (Sweden)

    Sunil Kumar Verma

    2016-01-01

    Full Text Available In the latter half of 2016, the important trials were ATMOSPHERE, INOVATE-HF, and IMPEDANCE-HF. The inclusion of angiotensin receptor–neprilysin inhibitor (valsartan/sacubitril and sinoatrial node modulator (ivabradine in the guidelines was a significant change. HOPE-3 was a major trial in 2016 expanding the dimension of statin use. ixCELL-DCM trial evaluated stem cells in dilated cardiomyopathy. Mobile-health and medication event monitoring system technology showed increasing use of technology in both prevention and treatment in cardiology. RIDDLE-non-ST-segment elevation myocardial infarction (NSTEMI studied the immediate versus delayed intervention in NSTEMI. In STEMI, DANAMI 3-DEFER trial evaluated the concept of immediate stent implantation or deferred stent implantation 48 h after the index procedure with standard primary percutaneous coronary intervention. EARLY-BAMI tested intravenous metoprolol in acute STEMI with the use of magnetic resonance imaging. The utility of “Chest Pain Choice” tool demonstrated shared decision-making between physician and patients in the context of chest pain. Risk factors profile and demographic and angiographic features of aorto-ostial atherosclerotic coronary artery disease are evaluated extensively. Transcatheter aortic valve replacement results in comparison to surgery and its association with volume, and in-hospital outcomes are also analyzed. The VANISH trial addressed a very critical issue in post-MI ICMP. Factors associated with erosion related to Amplatzer septal occluder in atrial septal defect closure are described in detail.

  13. Illustrating the (in)visible: Understanding the impact of loss in adults living with secondary lymphedema after cancer

    Science.gov (United States)

    Thomas, Roanne; Hamilton, Ryan

    2014-01-01

    Life with a disability is often riddled with paradoxes, one of which is being visibly marked, while personal experiences, losses, and challenges remain hidden. Our article draws attention to this paradox among people who live with secondary lymphedema after cancer (SLC). SLC is a relatively unfamiliar chronic condition within medical and lay discourses of cancer, which proves challenging for the many cancer survivors who are in search of information and understanding. Thirteen men and women with SLC were recruited from two research sites (Fredericton, NB, and Ottawa, ON, Canada) to participate in semi-structured interviews about the physical and psychosocial aspects of SLC. Using a methodology of interpretive description, our analysis of participant interviews reveals the complex ways in which men and women felt both visible and invisible within various contexts. We discuss three majors themes: (in)visibility and appearance related to material losses; (in)visibility and action connected to visible losses in function, as well as invisible struggles to care for oneself; and the loss of present and future well-being, as SLC renders some limitations visible while potentially obscuring a hopeful future indefinitely. Our research indicates that timely diagnosis of SLC would be an immediate first step in recognizing the physical and emotional dimensions of the condition. To accomplish this, increased awareness is needed. To enhance quality of life for those living with SLC, the development of new resources and psychosocial supports is also required. PMID:25148936

  14. Urban hospitality and the crowd. A discussion about sovereignty, states of exception, and inclusion in the urban public space based on some massive occupation processes in the city of São Paulo

    Directory of Open Access Journals (Sweden)

    Igor Guatelli

    2015-12-01

    Full Text Available In the wake of the protests that took place in mid 2013 in the city of São Paulo, this article investigates some collective and momentary massive occupation processes of the open public spaces in the city’s downtown area, whether under the aegis of the law or beyond the law. It can be said that the observation of intriguing and unstable ways of occupancy and appropriation of the public space – rather than stability of the built landscape – and their constant, momentary, and circumstantial rearrangement was the leitmotif for building a critical reflection on the uncertain paradoxical trends associated with contemporary collective public life. This study analyzed the territory as an inseparable relationship between normative pre-figurations and spontaneous momentary configurations of the urban space through appropriative, constant, and/or occasional flows. From everyday life to the most casual and incidental, what could have been thought based on this relation? Starting from this desubstantiated matter, another epistemological panorama about the present rises, riddled with paradoxalities. Ranging from the predictable, normalized, and standardized to the unexpected, urban space – changes in time – gave rise to a dimension important enough to be considered [and to be thought of] about the public “being” of the territory in some situations and occasions.

  15. Demystifying animal 'personality' (or not): why individual variation matters to experimental biologists.

    Science.gov (United States)

    Roche, Dominique G; Careau, Vincent; Binning, Sandra A

    2016-12-15

    Animal 'personality', defined as repeatable inter-individual differences in behaviour, is a concept in biology that faces intense controversy. Critics argue that the field is riddled with terminological and methodological inconsistencies and lacks a sound theoretical framework. Nevertheless, experimental biologists are increasingly studying individual differences in physiology and relating these to differences in behaviour, which can lead to fascinating insights. We encourage this trend, and in this Commentary we highlight some of the benefits of estimating variation in (and covariation among) phenotypic traits at the inter- and intra-individual levels. We focus on behaviour while drawing parallels with physiological and performance-related traits. First, we outline some of the confusion surrounding the terminology used to describe repeatable inter-individual differences in behaviour. Second, we argue that acknowledging individual behavioural differences can help researchers avoid sampling and experimental bias, increase explanatory power and, ultimately, understand how selection acts on physiological traits. Third, we summarize the latest methods to collect, analyse and present data on individual trait variation. We note that, while measuring the repeatability of phenotypic traits is informative in its own right, it is only the first step towards understanding how natural selection and genetic architecture shape intra-specific variation in complex, labile traits. Thus, understanding how and why behavioural traits evolve requires linking repeatable inter-individual behavioural differences with core aspects of physiology (e.g. neurophysiology, endocrinology, energy metabolism) and evolutionary biology (e.g. selection gradients, heritability). © 2016. Published by The Company of Biologists Ltd.

  16. Portfolio Diversification in the South-East European Equity Markets

    Directory of Open Access Journals (Sweden)

    Zaimovic Azra

    2017-04-01

    Full Text Available Diversification potential enables investors to manage their risk and decrease risk exposure. Good diversification policy is a safety net that prevents a portfolio from losing its value. A well-diversified portfolio consists of different categories of property with low correlations, while highly correlated markets have the feature of low possibilities for diversification. The biggest riddle in the world of investments is to find the optimal portfolio within a set of available assets with limited capital. There are numerous studies and mathematical models that deal with portfolio investment strategies. These strategies take advantage of diversification by spreading risk over several financial assets. Modern portfolio theory seeks to find the optimal model with the best results. This paper tries to identify relationships between returns of companies traded in South-East European equity markets. A Markowitz mean-variance (MV portfolio optimization method is used to identify possibilities for diversification among these markets and world leading capital markets. This research also offers insight into to the level of integration of South-East European equity markets. Principal component analysis (PCA is used to determine components that describe the strong patterns and co-movements of the dataset. Finally, we combined MV efficient frontier and equity, which represent PCA components, to draw conclusions. Our findings show that PC analysis substantially simplifies asset selection process in portfolio management. The results of the paper have practical applications for portfolio investors.

  17. From medicine to natural philosophy: Francis Hauksbee's way to the air-pump.

    Science.gov (United States)

    Brundtland, Terje

    2008-06-01

    Francis Hauksbee (1660-1713) is well known for his double-barrelled air-pump. However, the origin of this pump, and Hauksbee's background, are often described as a mystery. This text seeks to dispel the riddle. It is argued that Hauksbee's competence as an exceptional maker of air-pumps was developed between 1699 and 1703 as a result of his experiences with the construction, manufacturing and sale of cupping-glasses. His cupping utensils embodied a new design, where syringes were used to evacuate the glasses, instead of the traditional way by fire or mouth suction. These syringes, which in fact were small air-pumps, were perfected between 1699 and 1701. A larger syringe, introduced in 1701, served as a transition from the cupping-syringe to his first air-pump for use in natural philosophy. This syringe was described as a 'combined engine', which could serve as an air-pump, a condensing engine and a syringe for injecting air, wax or mercury into pathological specimens. Hauksbee's first air-pump was a single-barrelled model introduced in 1702, based on the combined engine. Its various features, such as easy and convenient leak-tightening, exact pressure measurements by an in-built barometer and an air-inlet function for readmission of air into the receiver, are discussed. Finally, it is shown that these activities gave Hauksbee the reputation of being an outstanding instrument-maker, years before the double-barrelled air-pump was in sight.

  18. National Survey Results: Retention of Women in Collegiate Aviation

    Science.gov (United States)

    Turney, Mary Ann; Bishop, James C.; Karp, Merrill R.; Niemczyk, Mary; Sitler, Ruth L.; Green, Mavis F.

    2002-01-01

    Since the numbers of women pursuing technical careers in aviation continues to remain very low, a study on retention of women was undertaken by a team of university faculty from Embry Riddle Aeronautical University, Arizona State University, and Kent State University. The study was initiated to discover the factors that influence women once they have already selected an aviation career and to ascertain what could be done to support those women who have demonstrated a serious interest in an aviation career by enrolling in a collegiate aviation program. This paper reports preliminary results of data collected in the first and second years of the study. The data was collected from surveys of 390 college students (195 women and 195 men) majoring in aviation programs in nine colleges and universities, representing widely varied geographic areas and including both two- and four-year institutions. Results revealed significant areas of concern among women in pilot training. When queried about these concerns, differences were evident in the responses of the male and female groups. These differences were expected. However, a surprising finding was that women in early stages of pilot training responded differently from women in more experienced stages, These response differences did not occur among the men surveyed. The results, therefore, suggest that women in experienced stages of training may have gone through an adaptation process and reflect more male-like attitudes about a number of objects, including social issues, confidence, family, and career.

  19. Political economy of hope as a cultural facet of biomedicalization: A qualitative examination of constraints to hospice utilization among U.S. end-stage cancer patients.

    Science.gov (United States)

    Mrig, Emily Hammad; Spencer, Karen Lutfey

    2018-03-01

    A growing body of social science literature is devoted to describing processes of biomedicalization. The issue of biomedicalization is especially relevant for individuals suffering from end-stage cancer and hoping that aggressive end-of-life interventions, which are riddled with uncertainty around quantity or quality of life, will produce a 'cure'. To examine hospice underutilization among end-stage cancer patients, we apply the anthropological concept 'political economy of hope,' which describes how personal and collective 'hope' is associated with the political and economic structures that produce biomedicalization processes. Previous studies have examined hospice underutilization among end-stage cancer patients and have identified barriers stemming from patient and physician characteristics or health insurance reimbursement policies. Yet, these studies do not provide an organized synthesis of how barriers articulate, how they are part of the longitudinal decision-making process, or describe the sociocultural context surrounding hospice care enrollment decisions. This paper focuses on US-specific mechanisms and is based on qualitative, in-depth, interviews with physicians at an academic hospital (N = 24). We find that hospice underutilization results from a web of interconnected constraints surrounding end-stage cancer patients. Our research reveals how hospice care contradicts the political and economic structures associated with end-stage cancer care and illustrates how end-stage cancer patients are transformed into a form of biovalue, a fundamental commodity sustaining the political economy of hope. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. The OMICS of Sports & Space: How Genomics is Transforming Both Fields

    Science.gov (United States)

    Reeves, Katherine

    2016-01-01

    Join top 10 New York Times Bestseller “The Sports Gene” author David Epstein and NASA Twins Study investigator Christopher E. Mason, Ph.D., in the debate as old as physical competition—nature versus nurture. From personal experience, Epstein tackles the great debate and traces how far science has come in solving this timeless riddle, and how genetics has entered into the field of sports. He’s an investigative science reporter for ProPublica and longtime contributor to Sports Illustrated. Epstein will share insights into performance-enhancing drugs, the lucky genetics that separate a professional athlete from a less talented athlete, and his research into the death of a friend with Hypertrophic Cardiomyopathy (HCM).From an epigenomic viewpoint, Mason examines the benefits and risks for astronauts who face extreme spaceflight conditions and what it means for the future of human space travel. He is an associate professor in the Department of Physiology and Biophysics, The Feil Family Brain and Mind Research Institute (BMRI) & The Institute for Computational Biomedicine at Weill Cornell Medicine. He is also part of the Tri-Institutional Program on Computational Biology and a Medicine Fellow of Genomics, Ethics, and Law in the Information Society Project at Yale Law School.The study of omics shows tremendous potential in prevention, diagnosis and treatment of injuries and diseases but genetic discrimination and molecular privacy concerns are raised in both sports and space.

  1. Clinical and Biological Manifestation of RNF168 Deficiency in Two Polish Siblings

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    Barbara Pietrucha

    2017-12-01

    Full Text Available Germline mutations in the RING finger protein gene RNF168 have been identified in a combined immunodeficiency disorder called RIDDLE syndrome. Since only two patients have been described with somewhat different phenotypes, there is need to identify further patients. Here, we report on two Polish siblings with RNF168 deficiency due to homozygosity for a novel frameshift mutation, c.295delG, that was identified through exome sequencing. Both patients presented with immunoglobulin deficiency, telangiectasia, cellular radiosensitivity, and increased alpha-fetoprotein (AFP levels. The younger sibling had a more pronounced neurological and morphological phenotype, and she also carried an ATM gene mutation in the heterozygous state. Immunoblot analyses showed absence of RNF168 protein, whereas ATM levels and function were proficient in lymphoblastoid cells from both patients. Consistent with the absence of RNF168 protein, 53BP1 recruitment to DNA double-strand breaks (DSBs after irradiation was undetectable in lymphoblasts or primary fibroblasts from either of the two patients. γH2AX foci accumulated normally but they disappeared with significant delay, indicating a severe defect in DSB repair. A comparison with the two previously identified patients indicates immunoglobulin deficiency, cellular radiosensitivity, and increased AFP levels as hallmarks of RNF168 deficiency. The variability in its clinical expression despite similar cellular phenotypes suggests that some manifestations of RNF168 deficiency may be modified by additional genetic or epidemiological factors.

  2. Identification of a Recently Active Mammalian SINE Derived from Ribosomal RNA

    Science.gov (United States)

    Longo, Mark S.; Brown, Judy D.; Zhang, Chu; O’Neill, Michael J.; O’Neill, Rachel J.

    2015-01-01

    Complex eukaryotic genomes are riddled with repeated sequences whose derivation does not coincide with phylogenetic history and thus is often unknown. Among such sequences, the capacity for transcriptional activity coupled with the adaptive use of reverse transcription can lead to a diverse group of genomic elements across taxa, otherwise known as selfish elements or mobile elements. Short interspersed nuclear elements (SINEs) are nonautonomous mobile elements found in eukaryotic genomes, typically derived from cellular RNAs such as tRNAs, 7SL or 5S rRNA. Here, we identify and characterize a previously unknown SINE derived from the 3′-end of the large ribosomal subunit (LSU or 28S rDNA) and transcribed via RNA polymerase III. This new element, SINE28, is represented in low-copy numbers in the human reference genome assembly, wherein we have identified 27 discrete loci. Phylogenetic analysis indicates these elements have been transpositionally active within primate lineages as recently as 6 MYA while modern humans still carry transcriptionally active copies. Moreover, we have identified SINE28s in all currently available assembled mammalian genome sequences. Phylogenetic comparisons indicate that these elements are frequently rederived from the highly conserved LSU rRNA sequences in a lineage-specific manner. We propose that this element has not been previously recognized as a SINE given its high identity to the canonical LSU, and that SINE28 likely represents one of possibly many unidentified, active transposable elements within mammalian genomes. PMID:25637222

  3. Vacating the Floodplain: Urban Property, Engineering, and Floods in Brisbane (1974-2011

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    Margaret Cook

    2017-01-01

    Full Text Available This article exposes the dominant socio-economic and political values that shaped flood management between 1974 and 2011 in Brisbane, Queensland, Australia. By the 1970s, international hazard scholarship advocated regulating land use as an effective flood mitigation tool. In 1974, floods devastated Southeast Queensland and highlighted the hazards of building on floodplains. Drawing on scholarship that frames floods as a cultural, rather than natural event, this paper shows that the state government of Queensland prioritised property development and continued to rely on dam building as a way of controlling floods. Dams were built with the aim of providing immunity from flooding, but tensions between State and local governments allowed both to evade responsibility for the growing hazard arising from continuing development in the floodplain. When legislation and regulations were introduced to control floodplain development, they reflected popular sentiment against land use restrictions and hence were limited in scope, non-mandatory, and riddled with loopholes. The results of these inadequate land use regulations and continued residential development below the 100-year flood level were fully exposed in 2011 when a substantial increase in damages accompanied flooding of the Brisbane River. Despite evidence and predictions of increased risk of more frequent and larger floods from a warming climate, both state and local governments have continued to promote development in the Brisbane River floodplain, and appear willing to subject the city and its residents to increased hazards and vulnerability.

  4. Atrial-selective K+ channel blockers: potential antiarrhythmic drugs in atrial fibrillation?

    Science.gov (United States)

    Ravens, Ursula

    2017-11-01

    In the wake of demographic change in Western countries, atrial fibrillation has reached an epidemiological scale, yet current strategies for drug treatment of the arrhythmia lack sufficient efficacy and safety. In search of novel medications, atrial-selective drugs that specifically target atrial over other cardiac functions have been developed. Here, I will address drugs acting on potassium (K + ) channels that are either predominantly expressed in atria or possess electrophysiological properties distinct in atria from ventricles. These channels include the ultra-rapidly activating, delayed outward-rectifying Kv1.5 channel conducting I Kur , the acetylcholine-activated inward-rectifying Kir3.1/Kir3.4 channel conducting I K,ACh , the Ca 2+ -activated K + channels of small conductance (SK) conducting I SK , and the two-pore domain K + (K2P) channels (tandem of P domains, weak inward-rectifying K + channels (TWIK-1), TWIK-related acid-sensitive K + channels (TASK-1 and TASK-3)) that are responsible for voltage-independent background currents I TWIK-1 , I TASK-1 , and I TASK-3 . Direct drug effects on these channels are described and their putative value in treatment of atrial fibrillation is discussed. Although many potential drug targets have emerged in the process of unravelling details of the pathophysiological mechanisms responsible for atrial fibrillation, we do not know whether novel antiarrhythmic drugs will be more successful when modulating many targets or a single specific one. The answer to this riddle can only be solved in a clinical context.

  5. Rhetoric versus reality: The role of research in deconstructing concepts of caring.

    Science.gov (United States)

    Freshwater, Dawn; Cahill, Jane; Esterhuizen, Philip; Muncey, Tessa; Smith, Helen

    2017-10-01

    Our aim was to employ a critical analytic lens to explicate the role of nursing research in supporting the notion of caring realities. To do this, we used case exemplars to illustrate the infusion of such discourses. The first exemplar examines the fundamental concept of caring: using Florence Nightingale's Notes on Nursing, the case study surfaces caring as originally grounded in ritualized practice and subsequently describes its transmutation, via competing discourses, to a more holistic concept. It is argued that in the many and varied attempts to define the dynamic concept of care, caring has now become paradoxically, a more fragmented concept despite attempts to render it more holistic and inclusive. In the second exemplar, one of the authors draws on her personal experience of the gap between theory and practice, so pronounced that it pushed the author to revisit the concept of evidence-based practice and nursing education. In our third and final exemplar, we refer to the absence of knowledge and practice generated through natural enquiry and curiosity, an absence which has led to production of corporate led rhetoric. Drawing together the central arguments of the three exemplars, we reflect on the influential role of nursing research in enabling the deconstruction of taken for granted assumptions such as caring, evidence-based practice and empowerment; assumptions which have been generated by discourses riddled with confusion and alienation from the reality of practice and the natural spirit of professional enquiry. © 2017 John Wiley & Sons Ltd.

  6. Animal Autobiography; Or, Narration beyond the Human

    Directory of Open Access Journals (Sweden)

    David Herman

    2016-10-01

    Full Text Available In engaging with acts of self-narration that cross species lines, creators of animal autobiographies also broach questions about genre, truth status, and the structure as well as the politics of narrative representation. To address these questions, the present article draws not just on scholarship on (animal autobiography but also on ideas from the fields of linguistic semantics, politeness theory, and discourse analysis, including the “framing and footing” approach that focuses on talk emerging in contexts of face-to-face interaction and that derives most directly from the work of Erving Goffman. On the basis of this research, and using case studies that range from animal riddles to Ceridwen Dovey’s Only the Animals (2014, a collection of life stories posthumously narrated by a variety of nonhuman tellers, I profile autobiographical acts that reach beyond the human as ways of speaking for or in behalf of animal others. Some animal autobiographies correlate with acts of telling for which humans themselves remain the principals as well as authors; their animal animators remain relegated to the role of commenting on human institutions, values, practices, and artifacts. Other examples, however, can be read as co-authored acts of narrating in behalf of equally hybrid (or “humanimal” principals. These experiments with narration beyond the human afford solidarity-building projections of other creatures’ ways of being-in-the-world—projections that enable a reassessment, in turn, of forms of human being.

  7. Intersections of two isiZulu genderlects and the construction of 'skesana' identities

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    Thabo Msibi

    2015-09-01

    Full Text Available Drawing on Youdell’s (2000, 2005, 2006 work on identity formation, we examine in this article multiple performances of gender identities in relation to a particular language use among African men who engage in same-sex relations. Based on semi-ethnographic research and in-depth interviews with African men who are isiNgqumo speakers in the Durban metropolitan area in KwaZulu-Natal, this article portrays the intersectional nature of two genderlects. The isiNgqumo lexicon is characterised largely by what Zulu speakers refer to as “deep” lexicon, and a closer examination reveals that a substantial number of lexical items are drawn from the isiHlonipho variety of Zulu, also termed “isiHlonipho Sabafazi” (‘women’s language of respect’. Hlonipha (lit. ‘respect’ social actions and language use are representative of showing submissiveness towards males and other people who are considered superiors. On the basis of the experiences of men who engage in same-sex relations and who self-identify as skesana, we argue that an isiNgqumo variety that draws from the isiHlonipho lexicon represents a linguistic variety that is linked to a heteronormative and patriarchal cultural system which renders femininity an inferior subject position. Within this gendered order, certain linguistic expressions of isiNgqumo can create tension-riddled identity categories and allow for complex positioning for skesanas, many of whom draw on heteronormative and heteropoleric categories in the construction of their sexual and gender identities.

  8. Dialectical Behavioral Therapy for Adolescents (DBT-A: a clinical Trial for Patients with suicidal and self-injurious Behavior and Borderline Symptoms with a one-year Follow-up

    Directory of Open Access Journals (Sweden)

    Schneider Csilla

    2011-01-01

    Full Text Available Abstract Background To date, there are no empirically validated treatments of good quality for adolescents showing suicidality and non-suicidal self-injurious behavior. Risk factors for suicide are impulsive and non-suicidal self-injurious behavior, depression, conduct disorders and child abuse. Behind this background, we tested the main hypothesis of our study; that Dialectical Behavioral Therapy for Adolescents is an effective treatment for these patients. Methods Dialectical Behavioral Therapy (DBT has been developed by Marsha Linehan - especially for the outpatient treatment of chronically non-suicidal patients diagnosed with borderline personality disorder. The modified version of DBT for Adolescents (DBT-A from Rathus & Miller has been adapted for a 16-24 week outpatient treatment in the German-speaking area by our group. The efficacy of treatment was measured by a pre-/post- comparison and a one-year follow-up with the aid of standardized instruments (SCL-90-R, CBCL, YSR, ILC, CGI. Results In the pilot study, 12 adolescents were treated. At the beginning of therapy, 83% of patients fulfilled five or more DSM-IV criteria for borderline personality disorder. From the beginning of therapy to one year after its end, the mean value of these diagnostic criteria decreased significantly from 5.8 to 2.75. 75% of patients were kept in therapy. For the behavioral domains according to the SCL-90-R and YSR, we have found effect sizes between 0.54 and 2.14. During treatment, non-suicidal self-injurious behavior reduced significantly. Before the start of therapy, 8 of 12 patients had attempted suicide at least once. There were neither suicidal attempts during treatment with DBT-A nor at the one-year follow-up. Conclusions The promising results suggest that the interventions were well accepted by the patients and their families, and were associated with improvement in multiple domains including suicidality, non-suicidal self-injurious behavior, emotion

  9. Dialectical Behavioral Therapy for Adolescents (DBT-A): a clinical Trial for Patients with suicidal and self-injurious Behavior and Borderline Symptoms with a one-year Follow-up.

    Science.gov (United States)

    Fleischhaker, Christian; Böhme, Renate; Sixt, Barbara; Brück, Christiane; Schneider, Csilla; Schulz, Eberhard

    2011-01-28

    To date, there are no empirically validated treatments of good quality for adolescents showing suicidality and non-suicidal self-injurious behavior. Risk factors for suicide are impulsive and non-suicidal self-injurious behavior, depression, conduct disorders and child abuse. Behind this background, we tested the main hypothesis of our study; that Dialectical Behavioral Therapy for Adolescents is an effective treatment for these patients. Dialectical Behavioral Therapy (DBT) has been developed by Marsha Linehan - especially for the outpatient treatment of chronically non-suicidal patients diagnosed with borderline personality disorder. The modified version of DBT for Adolescents (DBT-A) from Rathus & Miller has been adapted for a 16-24 week outpatient treatment in the German-speaking area by our group. The efficacy of treatment was measured by a pre-/post- comparison and a one-year follow-up with the aid of standardized instruments (SCL-90-R, CBCL, YSR, ILC, CGI). In the pilot study, 12 adolescents were treated. At the beginning of therapy, 83% of patients fulfilled five or more DSM-IV criteria for borderline personality disorder. From the beginning of therapy to one year after its end, the mean value of these diagnostic criteria decreased significantly from 5.8 to 2.75. 75% of patients were kept in therapy. For the behavioral domains according to the SCL-90-R and YSR, we have found effect sizes between 0.54 and 2.14.During treatment, non-suicidal self-injurious behavior reduced significantly. Before the start of therapy, 8 of 12 patients had attempted suicide at least once. There were neither suicidal attempts during treatment with DBT-A nor at the one-year follow-up. The promising results suggest that the interventions were well accepted by the patients and their families, and were associated with improvement in multiple domains including suicidality, non-suicidal self-injurious behavior, emotion dysregulation and depression from the beginning of therapy to the

  10. Diabetes mellitus: Exploring the challenges in the drug development process

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    Julius A Vaz

    2012-01-01

    Full Text Available Diabetes mellitus has reached epidemic proportions and continues to be a major burden on society globally. The International Diabetes Federation (IDF estimated the global burden of diabetes to be 366 million in 2011 and predicted that by 2030 this will have risen to 552 million. In spite of newer and effective treatment options, newer delivery and diagnostic devices, stricter glycaemic targets, better treatment guidelines and increased awareness of the disease, baseline glycosylated hemoglobin remains relatively high in subjects diagnosed and treated with type 2 diabetes. The search continues for an ideal anti diabetic drug that will not only normalize blood glucose but also provide beta cell rest and possibly restoration of beta cell function. The development of anti diabetic drugs is riddled with fundamental challenges. The concept of beta cell rest and restoration is yet to be completely understood and proven on a long term. The ideal therapeutic approach to treating type 2 diabetes is not yet determined. Our understanding of drug safety in early clinical development is primarily limited to "Type A" reactions. Until marketing authorization most drugs are approved based on the principle of confirming non-inferiority with an existing gold standard or determining superiority to a placebo. The need to obtain robust pharmaco-economic data prior to marketing authorization in order to determine appropriate pricing of a new drug remains a major challenge. The present review outlines some of the challenges in drug development of anti-diabetic drugs citing examples of pulmonary insulin, insulin analogues, thiazolidinediones and the GLP1 analogues.

  11. Diabetes mellitus: Exploring the challenges in the drug development process.

    Science.gov (United States)

    Vaz, Julius A; Patnaik, Ashis

    2012-07-01

    Diabetes mellitus has reached epidemic proportions and continues to be a major burden on society globally. The International Diabetes Federation (IDF) estimated the global burden of diabetes to be 366 million in 2011 and predicted that by 2030 this will have risen to 552 million. In spite of newer and effective treatment options, newer delivery and diagnostic devices, stricter glycaemic targets, better treatment guidelines and increased awareness of the disease, baseline glycosylated hemoglobin remains relatively high in subjects diagnosed and treated with type 2 diabetes. The search continues for an ideal anti diabetic drug that will not only normalize blood glucose but also provide beta cell rest and possibly restoration of beta cell function. The development of anti diabetic drugs is riddled with fundamental challenges. The concept of beta cell rest and restoration is yet to be completely understood and proven on a long term. The ideal therapeutic approach to treating type 2 diabetes is not yet determined. Our understanding of drug safety in early clinical development is primarily limited to "Type A" reactions. Until marketing authorization most drugs are approved based on the principle of confirming non-inferiority with an existing gold standard or determining superiority to a placebo. The need to obtain robust pharmaco-economic data prior to marketing authorization in order to determine appropriate pricing of a new drug remains a major challenge. The present review outlines some of the challenges in drug development of anti-diabetic drugs citing examples of pulmonary insulin, insulin analogues, thiazolidinediones and the GLP1 analogues.

  12. EVOLUTION OF SPEECH: A NEW HYPOTHESIS

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    Shishir

    2016-03-01

    Full Text Available BACKGROUND The first and foremost characteristic of speech is that it is human. Speech is one characteristic feature that has evolved in humans and is by far the most powerful form of communication in the Kingdom Animalia. Today, human has established himself as an alpha species and speech and language evolution has made it possible. But how is speech possible? What anatomical changes have made us possible to speak? A sincere effort has been put in this paper to establish a possible anatomical answer to the riddle. METHODS The prototypes of the cranial skeletons of all the major classes of phylum vertebrata were studied. The materials were studied in museums of Wayanad, Karwar and Museum of Natural History, Imphal. The skeleton of mammal was studied in the Department of Anatomy, K. S. Hegde Medical Academy, Mangalore. RESULTS The curve formed in the base of the skull due to flexion of the splanchnocranium with the neurocranium holds the key to answer of how humans were able to speak. CONCLUSION Of course this may not be the only reason which participated in the evolution of speech like the brain also had to evolve and as a matter of fact the occipital lobes are more prominent in humans when compared to that of the lower mammals. Although, not the only criteria but it is one of the most important thing that has happened in the course of evolution and made us to speak. This small space at the base of the brain is the difference which made us the dominant alpha species.

  13. High GC content causes orphan proteins to be intrinsically disordered.

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    Walter Basile

    2017-03-01

    Full Text Available De novo creation of protein coding genes involves the formation of short ORFs from noncoding regions; some of these ORFs might then become fixed in the population. These orphan proteins need to, at the bare minimum, not cause serious harm to the organism, meaning that they should for instance not aggregate. Therefore, although the creation of short ORFs could be truly random, the fixation should be subjected to some selective pressure. The selective forces acting on orphan proteins have been elusive, and contradictory results have been reported. In Drosophila young proteins are more disordered than ancient ones, while the opposite trend is present in yeast. To the best of our knowledge no valid explanation for this difference has been proposed. To solve this riddle we studied structural properties and age of proteins in 187 eukaryotic organisms. We find that, with the exception of length, there are only small differences in the properties between proteins of different ages. However, when we take the GC content into account we noted that it could explain the opposite trends observed for orphans in yeast (low GC and Drosophila (high GC. GC content is correlated with codons coding for disorder promoting amino acids. This leads us to propose that intrinsic disorder is not a strong determining factor for fixation of orphan proteins. Instead these proteins largely resemble random proteins given a particular GC level. During evolution the properties of a protein change faster than the GC level causing the relationship between disorder and GC to gradually weaken.

  14. A philosophical analysis of the general methodology of qualitative research: a critical rationalist perspective.

    Science.gov (United States)

    Rudnick, Abraham

    2014-09-01

    Philosophical discussion of the general methodology of qualitative research, such as that used in some health research, has been inductivist or relativist to date, ignoring critical rationalism as a philosophical approach with which to discuss the general methodology of qualitative research. This paper presents a discussion of the general methodology of qualitative research from a critical rationalist perspective (inspired by Popper), using as an example mental health research. The widespread endorsement of induction in qualitative research is positivist and is suspect, if not false, particularly in relation to the context of justification (or rather theory testing) as compared to the context of discovery (or rather theory generation). Relativism is riddled with philosophical weaknesses and hence it is suspect if not false too. Theory testing is compatible with qualitative research, contrary to much writing about and in qualitative research, as theory testing involves learning from trial and error, which is part of qualitative research, and which may be the form of learning most conducive to generalization. Generalization involves comparison, which is a fundamental methodological requirement of any type of research (qualitative or other); hence the traditional grounding of quantitative and experimental research in generalization. Comparison--rather than generalization--is necessary for, and hence compatible with, qualitative research; hence, the common opposition to generalization in qualitative research is misdirected, disregarding whether this opposition's claims are true or false. In conclusion, qualitative research, similar to quantitative and experimental research, assumes comparison as a general methodological requirement, which is necessary for health research.

  15. Petrology of the 1995/2000 Magma of Copahue, Argentina

    Science.gov (United States)

    Goss, A.; Varekamp, J. C.

    2001-05-01

    Phreatomagmatic eruptions of Copahue in July/August,1995 and July/August 2000 produced mixed juvenile clasts, silica-rich debris from the hydrothermal system, and magmatic scoria with 88 percent SiO2. These high-SiO2 clasts carry an as yet unidentified (crystobalite?), euhedral silica phase in great abundance, which is riddled with tan, primary melt inclusions. The mixed clasts have bands of mafic material with small euhedral olivine, clinopyroxene, and plagioclase that are mixed with an intermediate magma with coarser, resorbed phenocrysts of olivine, plagioclase, clino- and ortho- pyroxene, and rare occurrences of the silica phase. These ejecta are intimate mixtures of a relatively felsic magma similar to Pleistocene Copahue lavas and a mafic basaltic andesite, with minor contributions of a magma contaminated with silica-rich hydrothermal wallrock material. Two-pyroxene geothermometry indicates crystallization temperatures of 1020 deg - 1045 deg C. Glass inclusions (59-63 percent SiO2) in plagioclase and olivine crystals yield very low volatile contents in the melt (0.4-1.5 percent H2O). The 1995/2000 magmas resided at shallow level and degassed into the active volcano-hydrothermal system which discharges acid fluids into the Copahue crater lake and hot springs. More mafic magma intruded this shallow batch and the mixture rose into the hydrothermal system and assimilated siliceous wall rock. A Ti-diffusion profile in a magnetite crystal suggests that the period between magma mixing and eruption was on the order of 4-10 weeks, and the temperature difference between resident and intruding magma was about 50-60 oC.

  16. Multiple attractors and crisis route to chaos in a model food-chain

    International Nuclear Information System (INIS)

    Upadhyay, Ranjit Kumar

    2003-01-01

    An attempt has been made to identify the mechanism, which is responsible for the existence of chaos in narrow parameter range in a realistic ecological model food-chain. Analytical and numerical studies of a three species food-chain model similar to a situation likely to be seen in terrestrial ecosystems has been carried out. The study of the model food chain suggests that the existence of chaos in narrow parameter ranges is caused by the crisis-induced sudden death of chaotic attractors. Varying one of the critical parameters in its range while keeping all the others constant, one can monitor the changes in the dynamical behaviour of the system, thereby fixing the regimes in which the system exhibits chaotic dynamics. The computed bifurcation diagrams and basin boundary calculations indicate that crisis is the underlying factor which generates chaotic dynamics in this model food-chain. We investigate sudden qualitative changes in chaotic dynamical behaviour, which occur at a parameter value a 1 =1.7804 at which the chaotic attractor destroyed by boundary crisis with an unstable periodic orbit created by the saddle-node bifurcation. Multiple attractors with riddled basins and fractal boundaries are also observed. If ecological systems of interacting species do indeed exhibit multiple attractors etc., the long term dynamics of such systems may undergo vast qualitative changes following epidemics or environmental catastrophes due to the system being pushed into the basin of a new attractor by the perturbation. Coupled with stochasticity, such complex behaviours may render such systems practically unpredictable

  17. Policy instruments for energy conservation and environmental policy in the Netherlands

    Energy Technology Data Exchange (ETDEWEB)

    Bovenberg, A.L. [Tinbergen Inst., Rotterdam (Netherlands)

    1992-03-01

    In this paper it is assumed that the policy objective is not so much to economize on energy as to reduce pollution. In particular, to curb the emissions of carbon dioxide. A number of environmental policy instruments pertaining to fossil fuels are analyzed, mainly in the context of the Dutch economy: regulation, subsidies, voluntary agreements with industry, and taxation. At the moment, most industrial countries, including the Netherlands, rely almost entirely on the first three instruments. More recently, however, there has been a growing interest in environmental taxation. The theory that taxation is always and everywhere the best instrument assumes, however, perfect markets and a closed economy. Most economies, including the Dutch one, are riddled with market imperfections. Hence, policy makers confront a second best case. This implies that in selecting policy instruments, they have to resort to a more pragmatic `case-by-case` approach. A diversified diet is advocated. Taxation is part of that diet. Section 2 explores a number of important advantages of the tax instrument. Section 3 discusses a number of problems if a small open economy like the Netherlands would unilaterally adopt such a tax, especially if that tax would include energy-intensive firms that are subject to international competition. In this connection, some alternative policy instruments are analyzed in Section 4. Section 5 proceeds by investigating the case of international coordination and explores the conditions under which coordinated taxes could be successful. Section 6 analyzes policies targeted at households and at firms that are not subject to international competition. 13 refs.

  18. Cryogenic scintillators for rare events detection in the Edelweiss and EURECA experiments

    International Nuclear Information System (INIS)

    Verdier, M.A.

    2010-10-01

    The riddle of the dark matter in astrophysics could be solved by the detection of WIMPs (Weakly Interactive Massive Particles), particles that are predicted by supersymmetry. The direct detection of WIMPs requires a large mass of detectors, able to identify these particles in the background of natural radioactivity and cosmic rays. This thesis takes place within the framework of the EDELWEISS and the future EURECA experiments. These experiments use a technology based on two channel cryogenic detectors (bolometers), working at a few tens of mK. They are composed of crystals in which the energy deposited by particle interactions will produce a temperature increase (phonon signal), and where the ionization of the crystals results in either a charge or photon signal, depending on their nature. In order to broaden the range of targets for scintillating bolometers, we have built a setup to study the scintillation of crystals cooled down to 3 K. It is based on a cryostat with a compact optical geometry allowing enhanced light collection. Thanks to an individual photon counting technique and a statistical treatment of data, it allows us to measure the evolution of the the light yields and the decay time components between room temperature and 3 K. Thus this thesis presents the results obtained at 3 K on two well known room temperature crystals: BGO (Bi 4 Ge 3 O 12 ) and BaF 2 . We also study the luminescence properties of titanium sapphire (Ti:Al 2 O 3 ), under VUV excitation cooled down to 8 K. (author)

  19. A patient safety course for preclinical medical students.

    Science.gov (United States)

    Shekhter, Ilya; Rosen, Lisa; Sanko, Jill; Everett-Thomas, Ruth; Fitzpatrick, Maureen; Birnbach, David

    2012-12-01

    We developed a course to introduce incoming third-year medical students to the subject of patient safety, to focus their attention on teamwork and communication, and to create an awareness of patient-safe practices that will positively impact their performance as clinicians. The course, held prior to the start of clinical rotations, consisted of lectures, web-based didactic materials, small group activities and simulation exercises, with an emphasis on experiential learning. First, students inspected a 'room of horrors', which is a simulated clinical environment riddled with errors. Second, we used lenticular puzzles in small groups to elicit teamwork behaviours that parallel real-life interactions in health care. Each team was given 8 minutes to complete a 48-piece puzzle, with five pieces removed at random and given to other teams. The salient teaching point of this exercise is that for a team to complete the task, team members must communicate with members of their own team as well as with other teams. Last, simulation scenarios provided a clinical context to reinforce the skills introduced through the puzzle exercise and lectures. The students were split into groups of six or seven members and challenged with two scenarios. Both scenarios focused on a 56-year-old man in respiratory distress. The teams were debriefed on both clinical management and teamwork. The vast majority of the students (93%) agreed that the course improved their patient safety knowledge and skills. The positive response from students to the introductory course is an important step in fostering a culture of patient safety. © Blackwell Publishing Ltd 2012.

  20. Fault Tree Analysis for Safety/Security Verification in Aviation Software

    Directory of Open Access Journals (Sweden)

    Andrew J. Kornecki

    2013-01-01

    Full Text Available The Next Generation Air Traffic Management system (NextGen is a blueprint of the future National Airspace System. Supporting NextGen is a nation-wide Aviation Simulation Network (ASN, which allows integration of a variety of real-time simulations to facilitate development and validation of the NextGen software by simulating a wide range of operational scenarios. The ASN system is an environment, including both simulated and human-in-the-loop real-life components (pilots and air traffic controllers. Real Time Distributed Simulation (RTDS developed at Embry Riddle Aeronautical University, a suite of applications providing low and medium fidelity en-route simulation capabilities, is one of the simulations contributing to the ASN. To support the interconnectivity with the ASN, we designed and implemented a dedicated gateway acting as an intermediary, providing logic for two-way communication and transfer messages between RTDS and ASN and storage for the exchanged data. It has been necessary to develop and analyze safety/security requirements for the gateway software based on analysis of system assets, hazards, threats and attacks related to ultimate real-life future implementation. Due to the nature of the system, the focus was placed on communication security and the related safety of the impacted aircraft in the simulation scenario. To support development of safety/security requirements, a well-established fault tree analysis technique was used. This fault tree model-based analysis, supported by a commercial tool, was a foundation to propose mitigations assuring the gateway system safety and security. 

  1. A renovação da teleologia em Hans Jonas: da biologia filosófica aos fundamentos da ética

    Directory of Open Access Journals (Sweden)

    Wendell Evangelista Soares Lopes

    2010-12-01

    Full Text Available The present paper aims to elucidate the renewal of teleology in the thought of Hans Jonas showing how it takes up two central functions, namely: to think a philosophical biology – or ontology – that more accurately meets the construction of a coming-to-be and psychophysical universe; and to think the ought-to-be of humanity as the telos and absolute value in the evolutionary process of Being. To accomplish our goal, we explain first that what Jonas calls the “riddle of subjectivity” is the basic problem of ontology, and that modern philosophy fails to respond to it, thus requiring a rehabilitation – and renewal – of a teleological conception of being. Then we will show that this renewal of teleology, that can be called “neo-finalism”, defines finalism as intrinsic not only to individual beings, but also to the devenir of the world itself, where man would be the very ultimate realization of a latent possibility within this evolutionary process of the universal substance. Hence would result a principle of ethics which is ultimately grounded neither in the autonomy of the self nor in the needs of community, but in the teleological character of the evolutionary process of nature itself – man as the “final quality”, and thus the absolute value, of such a process. That is to say, for Jonas teleology aims to finally answer what is the good about humanity, who would sign as well as the very foundation of ethics.

  2. The evolution of cooperation in spatial groups

    International Nuclear Information System (INIS)

    Zhang Jianlei; Zhang Chunyan; Chu Tianguang

    2011-01-01

    Research highlights: → We propose a model of evolutionary games in which individuals are organized into networked groups. → We show that the social dilemma can be resolved and high cooperation levels are attained. → Larger average group size would lead to lower cooperation level but higher average payoffs. → The results show that higher expectations can bring the system with larger average payoffs. - Abstract: Much of human cooperation remains an evolutionary riddle. There is evidence that individuals are often organized into groups in many social situations. Inspired by this observation, we propose a simple model of evolutionary public goods games in which individuals are organized into networked groups. Here, nodes in the network represent groups; the edges, connecting the nodes, refer to the interactions between the groups. Individuals establish public goods games with partners in the same group and migrate among neighboring groups depending on their payoffs and expectations. We show that the paradigmatic public goods social dilemma can be resolved and high cooperation levels are attained in structured groups, even in relatively harsh conditions for cooperation. Further, by means of numerical simulations and mean-field analysis, we arrive at the result: larger average group size and milder cooperation environment would lead to lower cooperation level but higher average payoffs of the entire population. Altogether, these results emphasize that our understanding of cooperation can be enhanced by investigations of how spatial groups of individuals affect the evolution dynamics, which might help in explaining the emergence and evolution of cooperation.

  3. Center Planning and Development Student Engineer at KSC

    Science.gov (United States)

    Jenkins, Kenneth T., Jr.

    2015-01-01

    This summer I was the Student Trainee (Engineering) Pathways Intern (co-op) at the Kennedy Space Center (KSC) in the Center Planning & Development (CPD) Directorate. CPD works with commercial companies who are interested in using KSC's unique capabilities for spaceflight, spacecraft processing, ground systems and Research & Development (R&D) projects that fall in line with NASA's Mission and Vision. CPD is divided into three (3) groups: (1) AD-A, which works on the Master Planning for the center, (2) AD-B (where I am), which works on project control, management and integration, and (3) AD-C, which works on partnership development. CPD's main goal is to make KSC the world's preeminent multi-user spaceport and maintain the center as a leader in space exploration. CPD is a very diverse group of employees having a wide knowledge of not only the Space Shuttle, but also Expendable Launch Vehicles (ELV). The director of CPD, Scott Colloredo, is on the advisory board for Commercial Space Operations (CSO) and has a degree from ERAU. I worked on a number of different tasks for AD-B, as well as CPD, that includes, but not limited to: reviewing and reissuing engineering documents, weekly notes for CPD and senior management, engineering familiarizations with facilities at KSC, leading a tour for the Embry-Riddle Aeronautical University Career Services office, and working on actual agreements/proposals that will be used in the partnership process with multiple partners, along with other projects. Most of the work I have done is sensitive information and cannot be disclosed.

  4. Observation of L-bursts of Jupiter decameter waves

    International Nuclear Information System (INIS)

    Imai, Kazumasa; Tomisawa, Ichiro

    1978-01-01

    The Jupiter decameter waves are the only information source which can be obtained on the earth for the investigation of dynamics concerning the generation of plasma waves in the magnetosphere of Jupiter. The emission of Jupiter decameter waves is modulated by the satellite Io considerably. It is observed that the emission of decameter waves fluctuated much in course of time. The duration time of bursts is 1 to 10 sec and 1 to 50 msec for L-bursts and S-bursts, respectively. The simultaneous observations were conducted at two locations from August, 1977, and at three locations from December, 1977, for searching the source of L-bursts. The relation between the appearance frequency of L-bursts and S-bursts and Io phase and system 3 longitude is explained. The observation points were Sugadaira, Chofu and Toyokawa, The minimum detectable flux density by the wave receiving network is 10 -21 W/m 2 .Hz. Concerning the observed results, the locations of observed events on the Io phase and the system 3 longitude are shown. The analytical results on the L-bursts of the main source and the early source are explained, taking ten events. The analysed dynamic cross-correlation and the spectrum analysis of the decameter intensity are shown. The relation between the origin and the emission mechanism was investigated, considering the observed data and the evaluation mentioned above for the main source and early source, and the clue was obtained to solve the riddle of emission mechanism. (Nakai, Y.)

  5. Genome-Based Microbial Taxonomy Coming of Age.

    Science.gov (United States)

    Hugenholtz, Philip; Skarshewski, Adam; Parks, Donovan H

    2016-06-01

    Reconstructing the complete evolutionary history of extant life on our planet will be one of the most fundamental accomplishments of scientific endeavor, akin to the completion of the periodic table, which revolutionized chemistry. The road to this goal is via comparative genomics because genomes are our most comprehensive and objective evolutionary documents. The genomes of plant and animal species have been systematically targeted over the past decade to provide coverage of the tree of life. However, multicellular organisms only emerged in the last 550 million years of more than three billion years of biological evolution and thus comprise a small fraction of total biological diversity. The bulk of biodiversity, both past and present, is microbial. We have only scratched the surface in our understanding of the microbial world, as most microorganisms cannot be readily grown in the laboratory and remain unknown to science. Ground-breaking, culture-independent molecular techniques developed over the past 30 years have opened the door to this so-called microbial dark matter with an accelerating momentum driven by exponential increases in sequencing capacity. We are on the verge of obtaining representative genomes across all life for the first time. However, historical use of morphology, biochemical properties, behavioral traits, and single-marker genes to infer organismal relationships mean that the existing highly incomplete tree is riddled with taxonomic errors. Concerted efforts are now needed to synthesize and integrate the burgeoning genomic data resources into a coherent universal tree of life and genome-based taxonomy. Copyright © 2016 Cold Spring Harbor Laboratory Press; all rights reserved.

  6. Edibles and Other Offerings to Readers: The Politics of Gender and Food in Narrative Fiction

    Directory of Open Access Journals (Sweden)

    Colăcel Onoriu

    2016-11-01

    Full Text Available From the perspective of an apparently absent author, the rhetorical commonplaces of womanhood and nourishment are mentioned in the novels of Margaret Atwood, The Edible Woman (1969, and of Jillian Medoff, Hunger Point (2002. Although traditionally relegated to contextualizing devices, the unfolding of events makes a riddle out of cooking and eating for the purpose of dramatic effect. Reporting on what might come across as domestic chores points to the topicality of food intake as well as to all the drama eating disorders entail. In the background of events, the ‘whodunit’ and the ‘kitchen sink drama’ come together into one unlikely story. The benefits of hindsight make it possible to argue that celebrated feminist novels of the past century, i.e. The Edible Woman, provided later 21st century fiction, i.e. Hunger Point, with something more than narrative emphasis on binary gender relations. I find that the gender-roles debate, as recorded in Atwood’s work, gained enough cultural momentum to prove the ready availability of the image of the nurturing female throughout the 20th century and beyond. As far as feminist fictions are concerned, over/under-feeding is always somewhere in the background, if not what drives the plot forward. Commonly, distress among fictional characters, mostly women, is linked to body weight and dieting in ways that threaten to relegate, possibly once and for good, the notions of women and food to the realm of melodrama, as it is the case with Hunger point.

  7. Therapeutic efficacy and safety of propylthiouracil in psoriasis: An open-label study

    Directory of Open Access Journals (Sweden)

    Pushpa Gnanaraj

    2011-01-01

    Full Text Available Background: Psoriasis is a common hyperproliferative disorder of the skin associated with significant morbidity. Most of the drugs used in psoriasis provide only a temporary relief, whereas they are riddled with potential toxicities and cost concerns. Hence, there is a constant need to explore newer, effective, orally administered, and cost-effective drugs with minimal adverse effects. In this scenario, propylthiouracil (PTU, an antithyroid thioureylene has been shown to be effective in psoriasis which satisfies the above criteria. Aim: The objective of our study is to assess the clinical efficacy of PTU in psoriasis. Methods: A total of 25 patients with plaque psoriasis were treated with oral PTU for 12 weeks. Clinical response was assessed using the "Psoriasis Area and Severity Index" (PASI score. Routine blood analyses and thyroid function tests were carried out periodically during the study. Results: Oral PTU produced significant clearing of lesions at 6 weeks and 12 weeks of the study period in all patients, as demonstrated by the reduction in PASI scores (33.9% in 6 weeks and 74.1% reduction in 12 weeks. Four patients experienced near complete clearing of the lesions. One patient developed mild elevation of liver enzymes which reversed on withdrawal of PTU. None of the patients had hypothyroidism or cytopenias. Conclusion: PTU significantly clears the lesions in psoriasis with minimal adverse effects. Hence, it can be considered as a therapeutic option in psoriasis, especially when the standard drugs cannot be used due to their toxicities or forbidding cost.

  8. Sex Complexity and Politics in Black Dogs by Ian McEwan

    Science.gov (United States)

    Abbasiyannejad, Mina; Talif, Rosli

    Ian McEwan's Black Dogs (BD) is a story of socio-political conflict during the critical era of the Cold War. Black Dogs is riddled with party (political) domination and its outcomes in society. Europe is still suffering the consequences of the Second World War, perhaps the biggest war of the twentieth century. In the aftermath of such worldwide upheaval, the conflicts that were in tandem with the scramble for political domination emerged in diverse ways, affecting nations and their human populations. Systematic sexual assault during the war years showed that sex was used both for intimidation and humiliation. This study attempts to picture the multidimensional aspects of politics which are practically related to the most intimate human relationship, that is, sex. It pictures how personal is equated with the political and vice versa. The theory of sexual politics is the theoretical framework used to scrutinize power-structure relationship. By reviewing the major conflicts in such a scenario, as the Cold War, and societal restriction, this study concludes that conflict in the macrocosm (world and society) affects the microcosm (individual) in McEwan's Black Dogs. It provides a rather broad picture of politics and sexuality and highlights the stresses of wider society on human dysfunctional relationships. Rape as a tactic of war for a political goal demonstrates another aspect of sex. Reviewing the period in which the story takes place and relating it to the conflicts in society, the study goes beyond simple cause and effect problems among individuals and portrays a holistic view of sexuality and society.

  9. Security Operations Curriculum Package: BS in Global Security and Intelligence Studies, Security Operations Management Track, Embry-Riddle Aeronautical University, Prescott, AZ. BS in Security Operations Management, Model Curriculum

    Science.gov (United States)

    2011-10-24

    New York: Springer-Verlag. Harcourt, B. E. (2007). Against prediction: Profiling, policing, and punishing in an actuarial age...is not mathematically optimal for discovering rare 59 malfeasors. Proceedings of the National Academy of Sciences, http

  10. Ken Jacobs and the Perverted Archival Image

    Directory of Open Access Journals (Sweden)

    Gonçalo Pablo

    2016-12-01

    Full Text Available This paper analyses two recent works by American filmmaker Ken Jacobs that deal with aspects of remediation. The first is A Tom Tom Chaser, in which Jacobs records the telecine process that transforms the classic silent film Tom, Tom, the Piper’s Son from chemical into electronic media. The film is riddled with poetic turns inviting the audience to rediscover the medial noise hidden by images. Moreover, Jacobs focuses on the moment of transition from a material medium (the film strip to the immaterial (the image, the video, so that the noise brings the viewer closer to a perception or brief capture of the medium in itself. Images are both figured and disfigured along this process. The second work is The Guests, an unconventional 3D film in which Jacobs transforms a short take from a Lumière Brothers film by discovering unseen views of the original footage. In his remediation of the 3D technology, Jacobs employs the Pulfrich effect, which allows him to blur the images of the archival film and to create instances of uncertainty between the views coming from the two human eyes. As a result of this procedure, the characters in the film seem to look directly at the audience. The analysis of both films highlights the poetry of the typical manoeuvre by which Jacobs perverts the archival medium, whereupon the viewing mode between media denaturalizes the usual media gaze (framed and representational, focusing on the moment of viewing in itself. This, as a result, favours the medium for what it is and subverts the gaze that expects something representational, discursive, perhaps story-driven.

  11. He drove forward with a yell: anger in medicine and Homer.

    Science.gov (United States)

    Bleakley, A; Marshall, R; Levine, D

    2014-06-01

    We use Homer and Sun Tzu as a background to better understand and reformulate confrontation, anger and violence in medicine, contrasting an unproductive 'love of war' with a productive 'art of war' or 'art of strategy'. At first glance, it is a paradox that the healing art is not pacific, but riddled with militaristic language and practices. On closer inspection, we find good reasons for this cultural paradox yet regret its presence. Drawing on insights from Homer's The Iliad and The Odyssey, we argue for better understanding of confrontation, anger, bullying, intimidation and violence in medicine in order to change the culture. For example, equating medicine with war is not a given condition of medicine but a convenient metaphor with historical origins and a historical trajectory. Other, non-martial metaphors, such as medicine as collaboration, may be more appropriate in an age of team-based care. Taking lessons from Homer, we suggest three key ways in which cold-hearted confrontation and anger in medicine can be transformed into productive, warm-hearted engagement: the transformation of angry impulse into (1) reflection, (2) moral courage and (3) empathy. Thinking with Homer can offer an aesthetically and morally charged alternative to the current body of literature on topics, such as anger in doctors, and how this may be 'managed', without recourse to an instrumental economy where emotions are viewed as commodities, and emotional responses can be 'trained' through communication skills courses. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. Implementing Participatory Water Management: Recent Advances in Theory, Practice, and Evaluation

    Directory of Open Access Journals (Sweden)

    Yorck von Korff

    2012-03-01

    Full Text Available Many current water planning and management problems are riddled with high levels of complexity, uncertainty, and conflict, so-called "messes" or "wicked problems." The realization that there is a need to consider a wide variety of values, knowledge, and perspectives in a collaborative decision making process has led to a multitude of new methods and processes being proposed to aid water planning and management, which include participatory forms of modeling, planning, and decision aiding processes. However, despite extensive scientific discussions, scholars have largely been unable to provide satisfactory responses to two pivotal questions: (1 What are the benefits of using participatory approaches?; (2 How exactly should these approaches be implemented in complex social-ecological settings to realize these potential benefits? In the study of developing social-ecological system sustainability, the first two questions lead to a third one that extends beyond the one-time application of participatory approaches for water management: (3 How can participatory approaches be most appropriately used to encourage transition to more sustainable ecological, social, and political regimes in different cultural and spatial contexts? The answer to this question is equally open. This special feature on participatory water management attempts to propose responses to these three questions by outlining recent advances in theory, practice, and evaluation related to the implementation of participatory water management. The feature is largely based on an extensive range of case studies that have been implemented and analyzed by cross-disciplinary research teams in collaboration with practitioners, and in a number of cases in close cooperation with policy makers and other interested parties such as farmers, fishermen, environmentalists, and the wider public.

  13. J. J. Sakurai Prize for Theoretical Particle Physics Talk: The Boundless Horizons of Supercollider Physics

    Science.gov (United States)

    Quigg, Chris

    2011-04-01

    The Large Hadron Collider at CERN is moving the experimental frontier of particle physics to the domain of electroweak symmetry breaking, reaching energies around one trillion electron volts for collisions among the basic constituents of matter. We do not know what the new wave of exploration will find, but the discoveries we make and the new puzzles we encounter are certain to change the face of particle physics and echo through neighboring sciences. In this new world, we confidently expect to learn what sets electromagnetism apart from the weak interactions, with profound implications for deceptively simple questions: Why are there atoms? Why chemistry? What makes stable structures possible? A pivotal step will be finding the Higgs boson-or whatever takes its place -and exploring its properties. But we hope for much more. More predictive extensions of the electroweak theory, including dynamical symmetry breaking and supersymmetry, imply new kinds of matter that would be within reach of LHC experiments. We suspect that candidates for the dark matter of the Universe could also await discovery on the TeV scale. The strong interactions may hold their own surprises. As we unravel the riddle of electroweak symmetry breaking, prospects arise for other new insights: into the different forms of matter, the unity of quarks and leptons, and the nature of spacetime. The questions in play all seem linked to one another-and to the kinship of the weak and electromagnetic interactions. I will speak of the evolving dialogue between theory and experiment, highlighting the work before us. Fermilab is operated by the Fermi Research Alliance under contract no. DE-AC02-07CH11359 with the U.S. Department of Energy.

  14. Aniline is an inducer, and not a precursor, for indole derivatives in Rubrivivax benzoatilyticus JA2.

    Directory of Open Access Journals (Sweden)

    Mohammed Mujahid

    Full Text Available Rubrivivax benzoatilyticus JA2 and other anoxygenic photosynthetic bacteria produce indole derivatives when exposed to aniline, a xenobiotic compound. Though this phenomenon has been reported previously, the role of aniline in the production of indoles is still a biochemical riddle. The present study aims at understanding the specific role of aniline (as precursor or stimulator in the production of indoles and elucidating the biochemical pathway of indoles in aniline-exposed cells by using stable isotope approaches. Metabolic profiling revealed tryptophan accumulation only in aniline exposed cells along with indole 3-acetic acid (IAA and indole 3-aldehyde (IAld, the two major catabolites of tryptophan. Deuterium labelled aniline feeding studies revealed that aniline is not a precursor of indoles in strain JA2. Further, production of indoles only in aniline-exposed cells suggests that aniline is an indoles stimulator. In addition, production of indoles depended on the presence of a carbon source, and production enhanced when carbon sources were added to the culture. Isotope labelled fumarate feeding identified, fumarate as the precursor of indole, indicating de novo synthesis of indoles. Glyphosate (shikimate pathway inhibitor inhibited the indoles production, accumulation of tryptophan, IAA and IAld indicating that indoles synthesis in strain JA2 occurs via the de novo shikimate pathway. The up-regulation of anthranilate synthase gene and induction of anthranilate synthase activity correlated well with tryptophan production in strain JA2. Induction of tryptophan aminotransferase and tryptophan 2-monooxygenase activities corroborated well with IAA levels, suggesting that tryptophan catabolism occurs simultaneously in aniline exposed cells. Our study demonstrates that aniline (stress stimulates tryptophan/indoles synthesis via the shikimate pathway by possibly modulating the metabolic pathway.

  15. Neutral ISM, Ly α , and Lyman-continuum in the Nearby Starburst Haro 11

    Energy Technology Data Exchange (ETDEWEB)

    Rivera-Thorsen, T. Emil; Östlin, Göran; Hayes, Matthew; Puschnig, Johannes, E-mail: trive@astro.su.se [Department of Astronomy, Stockholm University, AlbaNova University Centre, SE-106 91 Stockholm (Sweden)

    2017-03-01

    Star-forming galaxies are believed to be a major source of Lyman continuum (LyC) radiation responsible for reionizing the early universe. Direct observations of escaping ionizing radiation have however been sparse and with low escape fractions. In the local universe, only 10 emitters have been observed, with typical escape fractions of a few percent. The mechanisms regulating this escape need to be strongly evolving with redshift in order to account for the epoch of reionization. Gas content and star formation feedback are among the main suspects, known to both regulate neutral gas coverage and evolve with cosmic time. In this paper, we reanalyze Hubble Space Telescope ( HST )-Cosmic Origins Spectrograph (COS) spectrocopy of the first detected local LyC leaker, Haro 11. We examine the connection between LyC leakage and Ly α line shape, and feedback-influenced neutral interstellar medium (ISM) properties like kinematics and gas distribution. We discuss the two extremes of an optically thin, density bounded ISM and a riddled, optically thick, ionization bounded ISM, and how Haro 11 fits into theoretical predictions. We find that the most likely ISM model is a clumpy neutral medium embedded in a highly ionized medium with a combined covering fraction of unity and a residual neutral gas column density in the ionized medium high enough to be optically thick to Ly α , but low enough to be at least partly transparent to LyC and undetected in Si ii. This suggests that star formation feedback and galaxy-scale interaction events play a major role in opening passageways for ionizing radiation through the neutral medium.

  16. A questão ecológica: entre a ciência e a ideologia/utopia de uma época The ecological issue: science and ideology, or the utopia of a time

    Directory of Open Access Journals (Sweden)

    Elmo Rodrigues da Silva

    1997-09-01

    Full Text Available A problemática atual da questão ambiental remete-nos à discussão histórica da racionalidade científica, sobretudo nas sociedades ocidentais contemporâneas, onde o conflito entre a relação homem/meio natural fica evidenciado. Pretendendo dar conta deste conflito, a ecologia constituída como disciplina científica destaca-se como um campo problemático da ciência que busca integrar diversas disciplinas em torno de si. Alguns movimentos sociais, orientando-se por uma "visão ecologizada" (ecossistêmica de mundo, partem para denunciar os impactos ambientais oriundos, dentre outros, do modelo tecno-industrial altamente poluidor, consumidor dos recursos naturais e gerador da atual desordem global da biosfera. Esses movimentos, sendo orientados por éticas diferenciadas, reivindicam mudanças do quadro social e ambiental da sociedade atual a fim de garantir as necessidades das futuras gerações.Our modern concern over the environment brings us to the historical discussion of Scientific Rationalism, principally in contemporary western society, where the conflict between Man and the Natural World is at its greatest. In an attempt to solve this conflict, Ecology, a field of science, stands out riddled with problems, seeking to draw subjects from other fields into its own. Following an "ecologized world view" (Ecosystemics, some social currents denounce the environmental impact of, technological and industrial models, highly pollutant and dependent on natural resources, generating the contemporary disorder in our biosphere. These movements, following different schools of thought, demand changes in society, taking into consideration the present and future state of the environment.

  17. PUZZLES – A CREATIVE WAY OF DEVELOPMENT OF LOGICAL THINKING

    Directory of Open Access Journals (Sweden)

    Milková, Eva

    2011-12-01

    Full Text Available Logical thinking of students should be enhanced at all levels of their studies. There are many possibilities how to achieve it. In the paper one possible way within the subjects “Discrete Mathematics” and “Discrete Methods and Optimization” dealing with graph theory and combinatorial optimization will be presented. These mathematical disciplines are powerful tools for teachers allowing them to develop logical thinking of students, increase their imagination and make them familiar with solutions to various problems. Thanks the knowledge gained within the subjects students should be able to describe various practical situations with the aid of graphs, solve the given problem expressed by the graph, and translate the solution back into the initial situation. Student engagement is crucial for successful education. Practical tasks and puzzles attract students to know more about the explained subject matter and to apply gained knowledge. There are an endless number of enjoyable tasks, puzzles and logic problems in books like “Mathematics is Fun”, in riddles magazines and on the Internet. In the paper, as an inspiration, four puzzles developing logical thinking appropriate to be solved using graph theory and combinatorial optimization will be introduced. On these puzzles of different level of difficulty the students’ ability to find out the appropriate graph-representation of the given task and solve it will be discussed as well. The author of the paper has been prepared with her students various multimedia applications dealing with objects appropriate to subject matter for more than 15 years. In the paper we also discuss a benefit of multimedia applications used as a support of subjects “Discrete Mathematics” and “Discrete Methods and Optimization”.

  18. Velocity mapping in the Lower Congo River: a first look at the unique bathymetry and hydrodynamics of Bulu Reach

    Science.gov (United States)

    Jackson, P. Ryan; Oberg, Kevin A.; Gardiner, Ned; Shelton, John

    2009-01-01

    The lower Congo River is one of the deepest, most powerful, and most biologically diverse stretches of river on Earth. The river’s 270 m decent from Malebo Pool though the gorges of the Crystal Mountains to the Atlantic Ocean (498 km downstream) is riddled with rapids, cataracts, and deep pools. Much of the lower Congo is a mystery from a hydraulics perspective. However, this stretch of the river is a hotbed for biologists who are documenting evolution in action within the diverse, but isolated, fish populations. Biologists theorize that isolation of fish populations within the lower Congo is due to barriers presented by flow structure and bathymetry. To investigate this theory, scientists from the U.S. Geological Survey and American Museum of Natural History teamed up with an expedition crew from National Geographic in 2008 to map flow velocity and bathymetry within target reaches in the lower Congo River using acoustic Doppler current profilers (ADCPs) and echo sounders. Simultaneous biological and water quality sampling was also completed. This paper presents some preliminary results from this expedition, specifically with regard to the velocity structure andbathymetry. Results show that the flow in the bedrock controlled Bulu reach of the lower Congo is highly energetic. Turbulent and secondary flow structures can span the full depth of flow (up to 165 m), while coherent bank-to-bank cross-channel flow structures are absent. Regions of flow separation near the banks are isolated from one another and from the opposite bank by high shear, high velocity zones with depth-averaged flow velocities that can exceed 4 m/s.

  19. The Oedipus Cycle: developmental mythology, Greek tragedy, and the sociology of knowledge.

    Science.gov (United States)

    Datan, N

    1988-01-01

    The Oedipus complex of Freud is based on the inevitability of the tragic fate of a man who fled his home to escape the prophecy of parricide. Thus, he fulfilled it by killing a stranger who proved to be his father. As Freud does, this consideration of the tragedy of Oedipus takes as its point of departure the inevitability of the confrontation between father and son. Where Freud looks to the son, however, I look to the father, who set the tragedy in motion by attempting to murder his infant son. Themes ignored in developmental theory but axiomatic in gerontology are considered in this study of the elder Oedipus. The study begins by noting that Oedipus ascended the throne of Thebes not by parricide but by answering the riddle of the Sphynx and affirming the continuity of the life cycle which his father denied. In the second tragedy of the Oedipus Cycle of Sophocles, Oedipus at Colonus, this affirmation is maintained. As Oedipus the elder accepts the infirmities of old age and the support of his daughter Antigone, Oedipus the king proves powerful up to the very end of his life when he gives his blessing not to the sons who had exiled him from Thebes, but to King Theseus who shelters him in his old age. Thus, the Oedipus cycle, in contrast to the "Oedipus complex," represents not the unconscious passions of the small boy, but rather the awareness of the life cycle in the larger context of the succession of the generations and their mutual interdependence. These themes are illuminated by a fuller consideration of the tragedy of Oedipus.

  20. Evolved stars as complex chemical laboratories - the quest for gaseous chemistry

    Science.gov (United States)

    Katrien Els Decin, Leen

    2015-08-01

    At the end of their life, most stars lose a large fraction of their mass through a stellar wind. The stellar winds of evolved (super)giant stars are the dominant suppliers for the pristine building blocks of the interstellar medium (ISM). Crucial to the understanding of the chemical life cycle of the ISM is hence a profound insight in the chemical and physical structure governing these stellar winds.These winds are really unique chemical laboratories in which currently more than 70 different molecules and 15 different dust species are detected. Several chemical processes such as neutral-neutral and ion-molecule gas-phase reactions, dust nucleation and growth, and photo-processes determine the chemical content of these winds. However, gas-phase and dust-nucleation chemistry for astronomical environments still faces many challenges. One should realize that only ˜15% of the rate coefficients for gas-phase reactions considered to occur in (inter/circum)stellar regions at temperatures (T) below 300K have been subject to direct laboratory determinations and that the temperature dependence of the rate constants is often not known; only ˜2% have rate constants at Tgrant, we are now in the position to solve some riddles involved in understanding the gas-phase chemistry in evolved stars. In this presentation, I will demonstrate the need for accurate temperature-dependent gas-phase reaction rate constants and will present our new laboratory equipment built to measure the rate constants for species key in stellar wind chemistry. Specifically, we aim to obtain the rate constants of reactions involving silicon- and sulphur bearing species and HCCO for 30

  1. Neutral ISM, Ly α , and Lyman-continuum in the Nearby Starburst Haro 11

    International Nuclear Information System (INIS)

    Rivera-Thorsen, T. Emil; Östlin, Göran; Hayes, Matthew; Puschnig, Johannes

    2017-01-01

    Star-forming galaxies are believed to be a major source of Lyman continuum (LyC) radiation responsible for reionizing the early universe. Direct observations of escaping ionizing radiation have however been sparse and with low escape fractions. In the local universe, only 10 emitters have been observed, with typical escape fractions of a few percent. The mechanisms regulating this escape need to be strongly evolving with redshift in order to account for the epoch of reionization. Gas content and star formation feedback are among the main suspects, known to both regulate neutral gas coverage and evolve with cosmic time. In this paper, we reanalyze Hubble Space Telescope ( HST )-Cosmic Origins Spectrograph (COS) spectrocopy of the first detected local LyC leaker, Haro 11. We examine the connection between LyC leakage and Ly α line shape, and feedback-influenced neutral interstellar medium (ISM) properties like kinematics and gas distribution. We discuss the two extremes of an optically thin, density bounded ISM and a riddled, optically thick, ionization bounded ISM, and how Haro 11 fits into theoretical predictions. We find that the most likely ISM model is a clumpy neutral medium embedded in a highly ionized medium with a combined covering fraction of unity and a residual neutral gas column density in the ionized medium high enough to be optically thick to Ly α , but low enough to be at least partly transparent to LyC and undetected in Si ii. This suggests that star formation feedback and galaxy-scale interaction events play a major role in opening passageways for ionizing radiation through the neutral medium.

  2. How do the rotavirus NSP4 and bacterial enterotoxins lead differently to diarrhea?

    Directory of Open Access Journals (Sweden)

    Vasseur Monique

    2007-03-01

    Full Text Available Abstract Rotavirus is the major cause of infantile gastroenteritis and each year causes 611 000 deaths worldwide. The virus infects the mature enterocytes of the villus tip of the small intestine and induces a watery diarrhea. Diarrhea can occur with no visible tissue damage and, conversely, the histological lesions can be asymptomatic. Rotavirus impairs activities of intestinal disaccharidases and Na+-solute symports coupled with water transport. Maldigestion of carbohydrates and their accumulation in the intestinal lumen as well as malabsorption of nutrients and a concomitant inhibition of water reabsorption can lead to a malabsorption component of diarrhea. Since the discovery of the NSP4 enterotoxin, diverse hypotheses have been proposed in favor of an additional secretion component in the pathogenesis of diarrhea. Rotavirus induces a moderate net chloride secretion at the onset of diarrhea, but the mechanisms appear to be quite different from those used by bacterial enterotoxins that cause pure secretory diarrhea. Rotavirus failed to stimulate Cl- secretion in crypt, whereas it stimulated Cl- reabsorption in villi, questioning, therefore, the origin of net Cl- secretion. A solution to this riddle was that intestinal villi do in fact secrete chloride as a result of rotavirus infection. Also, the overall chloride secretory response is regulated by a phospholipase C-dependent calcium signaling pathway induced by NSP4. However, the overall response is weak, suggesting that NSP4 may exert both secretory and subsequent anti-secretory actions, as did carbachol, hence limiting Cl- secretion. All these characteristics provide the means to make the necessary functional distinction between viral NSP4 and bacterial enterotoxins.

  3. Mapping Ring Particle Cooling across Saturn's Rings with Cassini CIRS

    Science.gov (United States)

    Brooks, Shawn M.; Spilker, L. J.; Edgington, S. G.; Pilorz, S. H.; Deau, E.

    2010-10-01

    Previous studies have shown that the rings' thermal inertia, a measure of their response to changes in the thermal environment, varies from ring to ring. Thermal inertia can provide insight into the physical structure of Saturn's ring particles and their regoliths. Low thermal inertia and quick temperature responses are suggestive of ring particles that have more porous or fluffy regoliths or that are riddled with cracks. Solid, coherent particles can be expected to have higher thermal inertias (Ferrari et al. 2005). Cassini's Composite Infrared Spectrometer has recorded millions of spectra of Saturn's rings since its arrival at Saturn in 2004 (personal communication, M. Segura). CIRS records far infrared radiation between 10 and 600 cm-1 (16.7 and 1000 µm) at focal plane 1 (FP1), which has a field of view of 3.9 mrad. Thermal emission from Saturn's rings peaks in this wavelength range. FP1 spectra can be used to infer ring temperatures. By tracking how ring temperatures vary, we can determine the thermal inertia of the rings. In this work we focus on CIRS observations of the shadowed portion of Saturn's rings. The thermal budget of the rings is dominated by the solar radiation absorbed by its constituent particles. When ring particles enter Saturn's shadow this source of energy is abruptly cut off. As a result, ring particles cool as they traverse Saturn's shadow. From these shadow observations we can create cooling curves at specific locations across the rings. We will show that the rings' cooling curves and thus their thermal inertia vary not only from ring to ring, but by location within the individual rings. This research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Copyright 2010 California Institute of Technology. Government sponsorship acknowledged.

  4. Simplicity-minded management. A practical guide to stripping complexity out of your organization.

    Science.gov (United States)

    Ashkenas, Ron

    2007-12-01

    Large organizations are by nature complex, but over the years new business challenges--globalization, innovative technologies, and regulations, to name a few--have conspired to add layer upon layer of complexity to corporate structure and management. Organizations have become increasingly ungovernable and unwieldy: Performance is declining, accountability is unclear, decision rights are muddy, and data are crunched repeatedly, often with no clear purpose in mind. To avoid frustration and inefficiency, executives need to systematically attack the causes of complexity in their companies. Ashkenas and his partners at Robert H. Schaffer & Associates have worked with dozens of firms to help them develop strategies for simplifying. In this article, the author details the elements of a simplicity-minded strategy: Streamline the structure; prune products, services, and features; build disciplined processes; and improve managerial habits. ConAgra Foods' experience illustrates how one company turned itself around through careful execution of a simplicity strategy. The packaged-food supplier had become enormously successful by acquiring well-known brands and then allowing them to operate autonomously, evolving into a $14 billion organization with more than 100 brands, a food services business, and a commodity trading operation. ConAgra, however, had no common method for reporting, tracking, or analyzing results. Over time, therefore, it became a highly unwieldy enterprise, riddled with inefficiencies and unable to communicate adequately with investors and other stakeholders. When CEO Gary Rodkin came on board, in 2005, he invested in a series of initiatives to combat complexity. The tactic not only made life easier for customers and employees but also saved millions of dollars in costs. This article has an online interactive questionnaire that can help you assess your own company's level of complexity.

  5. Probing HeII Reionization at z>3.5 with Resolved HeII Lyman Alpha Forest Spectra

    Science.gov (United States)

    Worseck, Gabor

    2017-08-01

    The advent of GALEX and COS have revolutionized our view of HeII reionization, the final major phase transition of the intergalactic medium. COS spectra of the HeII Lyman alpha forest have confirmed with high confidence the high HeII transmission that signifies the completion of HeII reionization at z 2.7. However, the handful of z>3.5 quasars observed to date show a set of HeII transmission 'spikes' and larger regions with non-zero transmission that suggest HeII reionization was well underway by z=4. This is in striking conflict with predictions from state-of-the-art radiative transfer simulations of a HeII reionization driven by bright quasars. Explaining these measurements may require either faint quasars or more exotic sources of hard photons at z>4, with concomitant implications for HI reionization. However, many of the observed spikes are unresolved in G140L spectra and are significantly impacted by Poisson noise. Current data cannot reliably probe the ionization state of helium at z>3.5.We request 41 orbits to obtain science-grade G130M spectra of the two UV-brightest HeII-transmitting QSOs at z>3.5 to confirm and resolve their HeII transmission spikes as an unequivocal test of early HeII reionization. These spectra are complemented by recently obtained data from 8m telescopes: (1) Echelle spectra of the coeval HI Lya forest to map the underlying density field that modulates the HeII absorption, and (2) Our dedicated survey for foreground QSOs that may source the HeII transmission. Our recent HST programs revealed the only two viable targets to resolve the z>3.5 HeII Lyman alpha forest, and to conclusively solve this riddle.

  6. Water in Nominally Anhydrous Minerals from Nakhlites and Shergottites

    Science.gov (United States)

    Peslier, Anne H.

    2013-01-01

    Estimating the amount of water in the interior of terrestrial planets has tremendous implications on our understanding of solar nebula evolution, planet formation and geological history, and extraterrestrial volcanism. Mars has been a recent focus of such enquiry with complementary datasets from spacecrafts, rovers and martian meteorite studies. In planetary interiors, water can be dissolved in fluids or melts and hydrous phases, but can also be locked as protons attached to structural oxygen in lattice defects in nominally anhydrous minerals (NAM) such as olivine, pyroxene, or feldspar [1-3]. Measuring water in Martian meteorite NAM is challenging because the minerals are fragile and riddled with fractures from impact processes that makes them break apart during sample processing. Moreover, curing the sample in epoxy causes problems for the two main water analysis techniques, Fourier transform infrared spectrometry (FTIR) and secondary ionization mass spectrometry (SIMS). Measurements to date have resulted in a heated debate on how much water the mantle of Mars contains. SIMS studies of NAM [4], amphiboles [5], and apatites [6-8] from Martian meteorites report finding enough water in these phases to infer that the martian mantle is as hydrous as that of the Earth. On the other hand, a SIMS study of glass in olivine melt inclusions from shergottites concludes that the Martian mantle is much drier [9]. The latter interpretation is also supported by the fact that most martian hydrous minerals generally have the relevant sites filled with Cl and F instead of H [10,11]. As for experimental results, martian basalt compositions can be reproduced using water as well as Cl in the parent melts [12,13]. Here FTIR is used to measure water in martian meteorite minerals in order to constrain the origin of the distribution of water in martian meteorite phases.

  7. A GIS analysis of the relationship between sinkholes, dry-well complaints and groundwater pumping for frost-freeze protection of winter strawberry production in Florida.

    Directory of Open Access Journals (Sweden)

    Mark D Aurit

    Full Text Available Florida is riddled with sinkholes due to its karst topography. Sometimes these sinkholes can cause extensive damage to infrastructure and homes. It has been suggested that agricultural practices, such as sprinkler irrigation methods used to protect crops, can increase the development of sinkholes, particularly when temperatures drop below freezing, causing groundwater levels to drop quickly during groundwater pumping. In the strawberry growing region, Dover/Plant City, Florida, the effects have caused water shortages resulting in dry-wells and ground subsidence through the development of sinkholes that can be costly to maintain and repair. In this study, we look at how frost-freeze events have affected West Central Florida over the past 25 years with detailed comparisons made between two cold-years (with severe frost-freeze events and a warm year (no frost-freeze events. We analyzed the spatial and temporal correlation between strawberry farming freeze protection practices and the development of sinkholes/dry well complaints, and assessed the economic impact of such events from a water management perspective by evaluating the cost of repairing and drilling new wells and how these compared with using alternative crop-protection methods. We found that the spatial distribution of sinkholes was non-random during both frost-freeze events. A strong correlation between sinkhole occurrence and water extraction and minimum temperatures was found. Furthermore as temperatures fall below 41°F and water levels decrease by more than 20 ft, the number of sinkholes increase greatly (N >10. At this time alternative protection methods such as freeze-cloth are cost prohibitive in comparison to repairing dry wells. In conclusion, the findings from this study are applicable in other agricultural areas and can be used to develop comprehensive water management plans in areas where the abstraction of large quantities of water occur.

  8. A GIS analysis of the relationship between sinkholes, dry-well complaints and groundwater pumping for frost-freeze protection of winter strawberry production in Florida.

    Science.gov (United States)

    Aurit, Mark D; Peterson, Robert O; Blanford, Justine I

    2013-01-01

    Florida is riddled with sinkholes due to its karst topography. Sometimes these sinkholes can cause extensive damage to infrastructure and homes. It has been suggested that agricultural practices, such as sprinkler irrigation methods used to protect crops, can increase the development of sinkholes, particularly when temperatures drop below freezing, causing groundwater levels to drop quickly during groundwater pumping. In the strawberry growing region, Dover/Plant City, Florida, the effects have caused water shortages resulting in dry-wells and ground subsidence through the development of sinkholes that can be costly to maintain and repair. In this study, we look at how frost-freeze events have affected West Central Florida over the past 25 years with detailed comparisons made between two cold-years (with severe frost-freeze events) and a warm year (no frost-freeze events). We analyzed the spatial and temporal correlation between strawberry farming freeze protection practices and the development of sinkholes/dry well complaints, and assessed the economic impact of such events from a water management perspective by evaluating the cost of repairing and drilling new wells and how these compared with using alternative crop-protection methods. We found that the spatial distribution of sinkholes was non-random during both frost-freeze events. A strong correlation between sinkhole occurrence and water extraction and minimum temperatures was found. Furthermore as temperatures fall below 41°F and water levels decrease by more than 20 ft, the number of sinkholes increase greatly (N >10). At this time alternative protection methods such as freeze-cloth are cost prohibitive in comparison to repairing dry wells. In conclusion, the findings from this study are applicable in other agricultural areas and can be used to develop comprehensive water management plans in areas where the abstraction of large quantities of water occur.

  9. [Production of accentuated personality traits in baroque opera : Opera buffa Arcifanfano-Re dei matti (1749)].

    Science.gov (United States)

    Brunner, J; Hirsch, T; Steger, F

    2016-05-01

    Madness served primarily as a form of amusement for the spectators in operas of the seventeenth century. This representation was far removed from clinical reality. This circumstance changed in the eighteenth century at the time when tragic madness emerged in numerous operas. The opera buffa Arcifanfano-Re dei matti (Arcifanfano-King of fools, premiered in 1749 in Venice, text by Carlo Goldoni 1707-1793 and music by Baldassare Galuppi 1706-1785), which continuously enacts a realm of fools and is meant to appear amusing, is riddled with psychopathological abnormalities for which a retrospective diagnosis is methodologically rejected. However, the opera presents many subjects for working out a typology of fools based on outlasting personality traits of the protagonists. The libretto is investigated. A musical analysis is spared. The conceptualized typology of fools in the opera, which is oriented towards the seven main vices or deadly sins serves, in the tradition of moral satire, to critically hold up a mirror to the audience to reflect their own vices by an amusing characterization of the latter. Historically classified, the treatment of fools by means of isolation, custody, locking up in cages as well as authoritarian measures of submission reflects the custom in those days before humanizing the treatment of people with mental illness in the course of the Enlightenment and the French Revolution. The opera Arcifanfano is essentially characterized by continuous madness. A typology of the fools can be worked out from the precise depiction of the personalities. A mirror is held up to the spectators in terms of vices, in the tradition of the contemporary baroque opera. At the same time, the opera can be classified psychiatrically and historically as a seismograph of its time when in the seventeenth and eighteenth centuries people with mental illness were isolated and incarcerated.

  10. An Investigation to Advance the Technology Readiness Level of the Centaur Derived On-orbit Propellant Storage and Transfer System

    Science.gov (United States)

    Silvernail, Nathan L.

    This research was carried out in collaboration with the United Launch Alliance (ULA), to advance an innovative Centaur-based on-orbit propellant storage and transfer system that takes advantage of rotational settling to simplify Fluid Management (FM), specifically enabling settled fluid transfer between two tanks and settled pressure control. This research consists of two specific objectives: (1) technique and process validation and (2) computational model development. In order to raise the Technology Readiness Level (TRL) of this technology, the corresponding FM techniques and processes must be validated in a series of experimental tests, including: laboratory/ground testing, microgravity flight testing, suborbital flight testing, and orbital testing. Researchers from Embry-Riddle Aeronautical University (ERAU) have joined with the Massachusetts Institute of Technology (MIT) Synchronized Position Hold Engage and Reorient Experimental Satellites (SPHERES) team to develop a prototype FM system for operations aboard the International Space Station (ISS). Testing of the integrated system in a representative environment will raise the FM system to TRL 6. The tests will demonstrate the FM system and provide unique data pertaining to the vehicle's rotational dynamics while undergoing fluid transfer operations. These data sets provide insight into the behavior and physical tendencies of the on-orbit refueling system. Furthermore, they provide a baseline for comparison against the data produced by various computational models; thus verifying the accuracy of the models output and validating the modeling approach. Once these preliminary models have been validated, the parameters defined by them will provide the basis of development for accurate simulations of full scale, on-orbit systems. The completion of this project and the models being developed will accelerate the commercialization of on-orbit propellant storage and transfer technologies as well as all in

  11. The evolution of stories: from mimesis to language, from fact to fiction.

    Science.gov (United States)

    Boyd, Brian

    2018-01-01

    Why a species as successful as Homo sapiens should spend so much time in fiction, in telling one another stories that neither side believes, at first seems an evolutionary riddle. Because of the advantages of tracking and recombining true information, capacities for event comprehension, memory, imagination, and communication evolved in a range of animal species-yet even chimpanzees cannot communicate beyond the here and now. By Homo erectus, our forebears had reached an increasing dependence on one another, not least in sharing information in mimetic, prelinguistic ways. As Daniel Dor shows, the pressure to pool ever more information, even beyond currently shared experience, led to the invention of language. Language in turn swiftly unlocked efficient forms of narrative, allowing early humans to learn much more about their kind than they could experience at first hand, so that they could cooperate and compete better through understanding one another more fully. This changed the payoff of sociality for individuals and groups. But true narrative was still limited to what had already happened. Once the strong existing predisposition to play combined with existing capacities for event comprehension, memory, imagination, language, and narrative, we could begin to invent fiction, and to explore the full range of human possibilities in concentrated, engaging, memorable forms. First language, then narrative, then fiction, created niches that altered selection pressures, and made us ever more deeply dependent on knowing more about our kind and our risks and opportunities than we could discover through direct experience. WIREs Cogn Sci 2018, 9:e1444. doi: 10.1002/wcs.1444 This article is categorized under: Cognitive Biology > Evolutionary Roots of Cognition Linguistics > Evolution of Language Neuroscience > Cognition. © 2017 The Author. WIREs Cognitive Science published by Wiley Periodicals, Inc.

  12. THE ENVIRONMENTAL LEGACY OF THE IXTOC-I OIL SPILL IN CAMPECHE SOUND, SOUTHWESTERN GULF OF MEXICO

    Directory of Open Access Journals (Sweden)

    Luis Arturo Soto

    2014-11-01

    Full Text Available The southwestern Gulf of Mexico constitutes an important subsystem within a Large Marine Ecosystem. Due to its high biodiversity, living resources and energy resources, this region is strategic in the national plans for social and economic development of Mexico. The discovery of fossil fuel reserves in the seabed of Campeche Sound in the 1970s promoted the rapid expansion of the national oil industry in offshore waters. Unfortunately, the accidental blowout of the most productive well (Ixtoc-I in June of 1979, caused the first–world massive oil spill in a tropical marine environment. More than 3.4 million of barrels of crude oil were liberated in an ecosystem formerly renowned for its pristine conditions. In the aftermath of this dreadful accident, an immediate concern emerged not only for the oil acute effects but also for the long-term environmental consequences derived from the residual hydrocarbon compounds accumulated in coastal environments of the southern Gulf of Mexico. The attempts to assess the magnitude of the environmental damage were strongly precluded by the lack of pre-spill information. Natural variability in the ecosystem and oil weathering-factors contributed to attenuate the acute pollution effects that lasted nine months. However, the post-spill environmental alterations caused by the Ixtoc-I blowout still remain unanswered. The sinking of the Deepwater Horizon oil platform in the deep-waters of the northern Gulf of Mexico, in 2010 rekindled our concern for the great risk involved for human lives and the health of shallow and deep sea habitats. The authors of this contribution offer their views on this environmental riddle from their own perspective as direct witnesses of the Ixtoc-I environmental tragedy.

  13. Observing Traveling Ionospheric Disturbances Caused by Tsunamis Using GPS TEC Measurements

    Science.gov (United States)

    Galvan, David A.; Komjathy, Attila; Hickey, Michael; Foster, James; Mannucci, Anthony J.

    2010-01-01

    Ground-based Global Positioning System (GPS) measurements of ionospheric Total Electron Content (TEC) show variations consistent with atmospheric internal gravity waves caused by ocean tsunamis following two recent seismic events: the American Samoa earthquake of September 29, 2009, and the Chile earthquake of February 27, 2010. Fluctuations in TEC correlated in time, space, and wave properties with these tsunamis were observed in TEC estimates processed using JPL's Global Ionospheric Mapping Software. These TEC estimates were band-pass filtered to remove ionospheric TEC variations with wavelengths and periods outside the typical range of internal gravity waves caused by tsunamis. Observable variations in TEC appear correlated with the tsunamis in certain locations, but not in others. Where variations are observed, the typical amplitude tends to be on the order of 1% of the background TEC value. Variations with amplitudes 0.1 - 0.2 TECU are observable with periods and timing affiliated with the tsunami. These observations are compared to estimates of expected tsunami-driven TEC variations produced by Embry Riddle Aeronautical University's Spectral Full Wave Model, an atmosphere-ionosphere coupling model, and found to be in good agreement in some locations, though there are cases when the model predicts an observable tsunami-driven signature and none is observed. These TEC variations are not always seen when a tsunami is present, but in these two events the regions where a strong ocean tsunami was observed did coincide with clear TEC observations, while a lack of clear TEC observations coincided with smaller tsunami amplitudes. There exists the potential to apply these detection techniques to real-time GPS TEC data, providing estimates of tsunami speed and amplitude that may be useful for early warning systems.

  14. Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci.

    Directory of Open Access Journals (Sweden)

    Christopher L Schardl

    Full Text Available The fungal family Clavicipitaceae includes plant symbionts and parasites that produce several psychoactive and bioprotective alkaloids. The family includes grass symbionts in the epichloae clade (Epichloë and Neotyphodium species, which are extraordinarily diverse both in their host interactions and in their alkaloid profiles. Epichloae produce alkaloids of four distinct classes, all of which deter insects, and some-including the infamous ergot alkaloids-have potent effects on mammals. The exceptional chemotypic diversity of the epichloae may relate to their broad range of host interactions, whereby some are pathogenic and contagious, others are mutualistic and vertically transmitted (seed-borne, and still others vary in pathogenic or mutualistic behavior. We profiled the alkaloids and sequenced the genomes of 10 epichloae, three ergot fungi (Claviceps species, a morning-glory symbiont (Periglandula ipomoeae, and a bamboo pathogen (Aciculosporium take, and compared the gene clusters for four classes of alkaloids. Results indicated a strong tendency for alkaloid loci to have conserved cores that specify the skeleton structures and peripheral genes that determine chemical variations that are known to affect their pharmacological specificities. Generally, gene locations in cluster peripheries positioned them near to transposon-derived, AT-rich repeat blocks, which were probably involved in gene losses, duplications, and neofunctionalizations. The alkaloid loci in the epichloae had unusual structures riddled with large, complex, and dynamic repeat blocks. This feature was not reflective of overall differences in repeat contents in the genomes, nor was it characteristic of most other specialized metabolism loci. The organization and dynamics of alkaloid loci and abundant repeat blocks in the epichloae suggested that these fungi are under selection for alkaloid diversification. We suggest that such selection is related to the variable life histories

  15. Growth, characterisation and electronic applications of amorphous hydrogenated carbon

    International Nuclear Information System (INIS)

    Paul, S.

    2000-11-01

    My thesis proposes solutions to a number of riddles associated with the material, hydrogenated amorphous carbon, (a-C:H). This material has lately generated interest in the electronic engineering community, owing to some remarkable properties. The characterisation of amorphous carbon films, grown by radio frequency plasma enhanced chemical vapour deposition has been reported. The coexistence of multiple phases in the same a-C:H film manifests itself in the inconsistent electrical behaviour of different parts of the film, thus rendering it difficult to predict the nature of films. For the first time, in this thesis, a reliable prediction of Schottky contact formation on a-C:H films is reported. A novel and simple development on a Scanning Electron Microscope, configured to study the electrical properties of the grown a-C:H films, has been reported. Since device performance is crucially linked to the density of states in the film, a study of the same was undertaken in my doctoral research. I present a mathematical formalism to estimate the density of states in a-C:H. The most commonly used metal, (aluminium), for contact formation on a-C:H films, has been concluded to be the least suitable. On the basis of the study presented in this thesis, copper and chromium are judged to be the best alternatives. The resilience of a-C:H/Si heterostructures under high voltages (upto 900 V) has been reported in this thesis for the first time. The performance of a-C:H grown at room temperature on GaAs, has been studied and concluded to be satisfactory on the basis of good adherence and low leakage currents. Such a structure was motivated by the applicability in Metal Insulator Semiconductor Field Effect Transistors (MISFET). (author)

  16. Plasmonic devices and sensors built from ordered nanoporous materials.

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, Benjamin W.; Kobayashi, Yoji (University of California, Berkeley); Houk, Ronald J. T.; Allendorf, Mark D.; Long, Jeffrey R. (University of California, Berkeley); Robertson, Ian M. (University of Illinois Urbana-Champaign, Urbana, IL); House, Stephen D. (University of Illinois Urbana-Champaign, Urbana, IL); Graham, Dennis D. (University of Illinois Urbana-Champaign, Urbana, IL); Talin, Albert Alec (National Institute of Standards & Technology, Gaithersburg, MD); Chang, Noel N. (University of Illinois Urbana-Champaign, Urbana, IL); El Gabaly Marquez, Farid

    2009-09-01

    The objective of this project is to lay the foundation for using ordered nanoporous materials known as metal-organic frameworks (MOFs) to create devices and sensors whose properties are determined by the dimensions of the MOF lattice. Our hypothesis is that because of the very short (tens of angstroms) distances between pores within the unit cell of these materials, enhanced electro-optical properties will be obtained when the nanopores are infiltrated to create nanoclusters of metals and other materials. Synthetic methods used to produce metal nanoparticles in disordered templates or in solution typically lead to a distribution of particle sizes. In addition, creation of the smallest clusters, with sizes of a few to tens of atoms, remains very challenging. Nanoporous metal-organic frameworks (MOFs) are a promising solution to these problems, since their long-range crystalline order creates completely uniform pore sizes with potential for both steric and chemical stabilization. We report results of synthetic efforts. First, we describe a systematic investigation of silver nanocluster formation within MOFs using three representative MOF templates. The as-synthesized clusters are spectroscopically consistent with dimensions {le} 1 nm, with a significant fraction existing as Ag{sub 3} clusters, as shown by electron paramagnetic resonance. Importantly, we show conclusively that very rapid TEM-induced MOF degradation leads to agglomeration and stable, easily imaged particles, explaining prior reports of particles larger than MOF pores. These results solve an important riddle concerning MOF-based templates and suggest that heterostructures composed of highly uniform arrays of nanoparticles within MOFs are feasible. Second, a preliminary study of methods to incorporate fulleride (K{sub 3}C{sub 60}) guest molecules within MOF pores that will impart electrical conductivity is described.

  17. Research Projects, Technical Reports and Publications

    Science.gov (United States)

    Oliger, Joseph

    1996-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. A flexible scientific staff is provided through a university faculty visitor program, a post doctoral program, and a student visitor program. Not only does this provide appropriate expertise but it also introduces scientists outside of NASA to NASA problems. A small group of core RIACS staff provides continuity and interacts with an ARC technical monitor and scientific advisory group to determine the RIACS mission. RIACS activities are reviewed and monitored by a USRA advisory council and ARC technical monitor. Research at RIACS is currently being done in the following areas: Advanced Methods for Scientific Computing High Performance Networks During this report pefiod Professor Antony Jameson of Princeton University, Professor Wei-Pai Tang of the University of Waterloo, Professor Marsha Berger of New York University, Professor Tony Chan of UCLA, Associate Professor David Zingg of University of Toronto, Canada and Assistant Professor Andrew Sohn of New Jersey Institute of Technology have been visiting RIACS. January 1, 1996 through September 30, 1996 RIACS had three staff scientists, four visiting scientists, one post-doctoral scientist, three consultants, two research associates and one research assistant. RIACS held a joint workshop with Code 1 29-30 July 1996. The workshop was held to discuss needs and opportunities in basic research in

  18. BREEDING SUPER-EARTHS AND BIRTHING SUPER-PUFFS IN TRANSITIONAL DISKS

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eve J.; Chiang, Eugene, E-mail: evelee@berkeley.edu, E-mail: echiang@astro.berkeley.edu [Department of Astronomy, University of California Berkeley, Berkeley, CA 94720-3411 (United States)

    2016-02-01

    The riddle posed by super-Earths (1–4R{sub ⊕}, 2–20M{sub ⊕}) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (in one case up to 9) orders of magnitude, and super-Earths can still robustly emerge after ∼0.1–1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to gravitationally stir one another and merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The basic picture—that close-in super-Earths form in a gas-poor (but not gas-empty) inner disk, fed continuously by gas that bleeds inward from a more massive outer disk—recalls the largely evacuated but still accreting inner cavities of transitional protoplanetary disks. We also address the inverse problem presented by super-puffs: an uncommon class of short-period planets seemingly too voluminous for their small masses (4–10R{sub ⊕}, 2–6M{sub ⊕}). Super-puffs most easily acquire their thick atmospheres as dust-free, rapidly cooling worlds outside ∼1 AU where nebular gas is colder, less dense, and therefore less opaque. Unlike super-Earths, which can form in situ, super-puffs probably migrated in to their current orbits; they are expected to form the outer links of mean-motion resonant chains, and to exhibit greater water content. We close by confronting observations and itemizing remaining questions.

  19. Universal screening as the great equalizer: Eliminating disproportionality in special education referrals

    Science.gov (United States)

    Raines, Tara C.

    The overrepresentation of minority students identified for special education services continues to plague schools and serves as a challenge for researchers and practitioners (Ferri & Conner, 2005). Teacher nomination, office discipline referrals (ODR), and functional behavior assessments (FBA) continue to guide referral processes (Bradshaw, Mitchell, O'Brennen, & Leaf, 2010; Eklund, et al., 2009; Mustian, 2010). These methods have been found to be riddled with inconsistencies. Practices used to identify students for behavioral and emotional interventions over-identify students from culturally and linguistically diverse backgrounds. The use of a behavioral and emotional screener to make data-based decisions regarding placement and services could provide an objective assessment of student risk. The first chapter of this dissertation reviews methods used in the identification of students for behavioral and emotional support services. Additionally, the use of universal screening in conjunction with student self-report are proposed as tools for alleviating the overrepresentation of minority students in special education programs for behavioral and emotional disorders. The second chapter of this dissertation explores the measurement equivalence of Behavior Assessment System for Children, Second Edition (BASC-2) Behavioral and Emotional Screening System Student form (BESS Student) across the Black, Hispanic, and White participants in the norming sample. The BESS Student as a universal screening tool is poised to alleviate the disproportionate number of children of color identified by schools as having behavior and emotional disorders. This instrument also provides an avenue to identify students with internalizing disorders who are often overlooked in present referral practices (Bradshaw, Buckley, & Ialongo, 2008; Kataoka, Zhang, & Wells, 2002). The findings of the measurement equivalence study suggests that the BESS Student is, as designed, identifying behavioral and

  20. Variations in Ring Particle Cooling across Saturn's Rings with Cassini CIRS

    Science.gov (United States)

    Brooks, S. M.; Spilker, L. J.; Pilorz, S.; Edgington, S. G.; Déau, E.; Altobelli, N.

    2010-12-01

    Cassini's Composite Infrared Spectrometer has recorded over two million of spectra of Saturn's rings in the far infrared since arriving at Saturn in 2004. CIRS records far infrared radiation between 10 and 600 cm-1 ( 16.7 and 1000 μ {m} ) at focal plane 1 (FP1), which has a field of view of 3.9 mrad. Thermal emission from Saturn’s rings peaks in this wavelength range. Ring temperatures can be inferred from FP1 data. By tracking how ring temperatures vary, we can determine the thermal inertia of the rings. Previous studies have shown that the rings' thermal inertia, a measure of their response to changes in the thermal environment, varies from ring to ring. Thermal inertia can provide insight into the physical structure of Saturn's ring particles and their regoliths. Low thermal inertia and rapidly changing temperatures are suggestive of ring particles that have more porous or fluffy regoliths or that are riddled with cracks. Solid particles can be expected to have higher thermal inertias. Ferrari et al. (2005) fit thermal inertia values of 5218 {Jm)-2 {K}-1 {s}-1/2 to their B ring data and 6412 {Jm)-2 {K}-1 {s}-1/2 to their C ring data. In this work we focus on CIRS observations of the shadowed portion of Saturn's rings. The rings’ thermal budget is dominated by its absorption of solar radiation. As a result, ring particles abruptly cool as they traverse Saturn's shadow. From these shadow observations we can create cooling curves at specific locations across the rings. We will show that the rings' cooling curves and thus their thermal inertia vary not only from ring to ring, but by location within the individual rings. This research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Copyright 2010 California Institute of Technology. Government sponsorship acknowledged.

  1. BREEDING SUPER-EARTHS AND BIRTHING SUPER-PUFFS IN TRANSITIONAL DISKS

    International Nuclear Information System (INIS)

    Lee, Eve J.; Chiang, Eugene

    2016-01-01

    The riddle posed by super-Earths (1–4R ⊕ , 2–20M ⊕ ) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (in one case up to 9) orders of magnitude, and super-Earths can still robustly emerge after ∼0.1–1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to gravitationally stir one another and merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The basic picture—that close-in super-Earths form in a gas-poor (but not gas-empty) inner disk, fed continuously by gas that bleeds inward from a more massive outer disk—recalls the largely evacuated but still accreting inner cavities of transitional protoplanetary disks. We also address the inverse problem presented by super-puffs: an uncommon class of short-period planets seemingly too voluminous for their small masses (4–10R ⊕ , 2–6M ⊕ ). Super-puffs most easily acquire their thick atmospheres as dust-free, rapidly cooling worlds outside ∼1 AU where nebular gas is colder, less dense, and therefore less opaque. Unlike super-Earths, which can form in situ, super-puffs probably migrated in to their current orbits; they are expected to form the outer links of mean-motion resonant chains, and to exhibit greater water content. We close by confronting observations and itemizing remaining questions

  2. Redox-sensitive self-assembled nanoparticles based on alpha-tocopherol succinate-modified heparin for intracellular delivery of paclitaxel.

    Science.gov (United States)

    Yang, Xiaoye; Cai, Xiaoqing; Yu, Aihua; Xi, Yanwei; Zhai, Guangxi

    2017-06-15

    To remedy the problems riddled in cancer chemotherapy, such as poor solubility, low selectivity, and insufficient intra-cellular release of drugs, novel heparin-based redox-sensitive polymeric nanoparticles were developed. The amphiphilic polymer, heparin-alpha-tocopherol succinate (Hep-cys-TOS) was synthesized by grafting hydrophobic TOS to heparin using cystamine as the redox-sensitive linker, which could self-assemble into nanoparticles in phosphate buffer saline (PBS) with low critical aggregation concentration (CAC) values ranging from 0.026 to 0.093mg/mL. Paclitaxel (PTX)-loaded Hep-cys-TOS nanoparticles were prepared via a dialysis method, exhibiting a high drug-loading efficiency of 18.99%. Physicochemical properties of the optimized formulation were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM) and differential scanning calorimetry (DSC). Subsequently, the redox-sensitivity of Hep-cys-TOS nanoparticles was confirmed by the changes in size distribution, morphology and appearance after dithiothreitol (DTT) treatment. Besides, the in vitro release of PTX from Hep-cys-TOS nanoparticles also exhibited a redox-triggered profile. Also, the uptake behavior and pathways of coumarin 6-loaded Hep-cys-TOS nanoparticles were investigated, suggesting the nanoparticles could be taken into MCF-7 cells in energy-dependent, caveolae-mediated and cholesterol-dependent endocytosis manners. Later, MTT assays of different PTX-free and PTX-loaded formulations revealed the desirable safety of PTX-free nanoparticles and the enhanced anti-cancer activity of PTX-loaded Hep-cys-TOS nanoparticles (IC 50 =0.79μg/mL). Apoptosis study indicated the redox-sensitive formulation could induce more apoptosis of MCF-7 cells than insensitive one (55.2% vs. 41.7%), showing the importance of intracellular burst release of PTX. Subsequently, the hemolytic toxicity confirmed the safety of the nanoparticles for intravenous administration. The results

  3. Repair response for DNA double-strand damage through ubiquitylation of chromatin

    International Nuclear Information System (INIS)

    Nakada, Shinichiro

    2011-01-01

    The chromatin modulation (remodeling) via lysine63 (K63)-linked ubiquitin (U) has been found important in the repair response for DNA double-strand damage, and the sequential signaling events at the damage site are explained. As the first step of the repair, MRN (MRE11, RAD50 and nibrin) complex recognizes the damage site and binds to it followed by many linked reactions by recruited and activated enzymes of various protein kinases and phosphatases, which resulting in the enhanced early signaling. As well, gamma-H2AX (phosphorylated histone H2AX) is yielded by the process, to which phosphorylated MDC1 (mediator of DNA-damage checkpoint 1) binds to produce their complex. Then further binding of RNF8-HERC2-UBC13 (ring finger protein 8, hect domain and RCC1 (CHC1)-like domain, and U conjugating enzyme E2N, respectively) occurs for starting the cumulative ubiquitylation of H2AX via K63 as the middle phase response. Signaling in the late phase occurs on the U chain formed at the damage site by binding of RAP (receptor-associated protein) 80 and other recruited 5 proteins like BRCA1 (breast cancer 1, early onset) to repair DNA by the homologous recombination after 53BP1 (tumor protein p53 binding protein) binding followed by methylation of histone H4. In a case of human compound heterozygous RNF168 defect, RIDDLE syndrome (radiosensitivity, immunodeficiency, dysmorphic features and learning difficulties), cells have no and slight abnormality of G2/M and intra-S checkpoint, respectively. Another defecting case with homozygous nonsense mutation has high radiosensitivity, intra-S checkpoint abnormality and others. Abnormality of immuno-globulins observed in both cases is similar to that in the RNF8-knockout mouse. Many tasks in chromatin ubiquitylation in the repair are still remained to be solved for protection and treatment of related diseases. (T.T.)

  4. Beyond Mathematics, a Standard Elementary Particle, and the Unified Field of Energy

    International Nuclear Information System (INIS)

    Sourial, A.S.

    2008-01-01

    Teaching methods are presented based on a theoretical logical thesis of: A Standard Elementary Particle, i nstead of the current 200 odd different subatomic particles, and their plausible derivation from such a standard particle, similar to the derivation of our body cells from a multi potential S tem Cell, T he thesis reintroduces the theory of A Material Ether a s a necessary medium for the transmission of the Electro-Magnetic-Gravitational Waves. It solves and demystifies the following riddles: 1. The A ether Vacuum, by offering a plausible composition of A n elastic solid medium, t hat meets the specific physical requirements needed for the transmission of the electro magnetic gravitational waves, Explains the vast amount of Potential Energy that such an A ether can carry, That there is No Action at a Distance, 2. It explains Q uantum Mechanics, o n simple Newtonian principles, It nullifies the H eisenberg Uncertainty Principle, s howing that there is no uncertainty whatsoever, for individual particle interactions, and the existence of F unctional Barriers f or the disc like aggregates of contiguous particles representing I ntra-atomic Electrons, a nd A full P hysical e xplanation of the their quantum numbers, their electronic shells, as well as: The Pauli Exclusion Principle. 3. The possible explanation of Hubbell's Law without an expansion of the Universe, that the C osmic Red Shift g ives the illusion of an expanding Universe similar to that of the B ent Stick i n the water due to refraction. 4. That the Big Bang I nflation Theory, f or the origin of the Universe is: a Figment of Imagination similar to Aladdin's D jinni out of the bottle. a nd a Fantasy of Mathematics with complete lack of touch with reality. The thesis suggests a plausible explanation - Modus Operandi - for, and composition of: i) Gravity, II) The structure of nucleons, III) The nature of the strong force, IV) The structure of the string of The String Theory

  5. [From reflex arc to psychic apparatus: neurology and psychoanalysis around 1900].

    Science.gov (United States)

    Porath, Erik

    2009-03-01

    As a disciple of Ernst Wilhelm von Brücke and Theodor Meynert, Sigmund Freud was familiar with 19th century physiology and neurology. He started his career with laboratory work and began later on, when being a young medic to develop an explicit psychological method for curating hysterics. These cases of hysteria ask riddles to the established medical discourse and practice. Freud's long time unpublished Entwurf einer Psychologie (1895) makes the attempt of a "psychology for the neurologist". He tried to give a sufficient theory of the psychic apparatus on the basis of natural science. At the same time he (together with Josef Breuer) published his Studies on Hysteria, which--in addition to his earlier essay on Aphasia (1891)--argued, that there is no clear cut relation between body and soul. Despite the dubious, non-reductive character of the soma-psyche-relation, Freud gave reason to search for a complex field of interrelations between the physiological and psychological knowledge, beyond the divide of natural sciences and humanities. Not until his groundbreaking Traumdeutung (1900) Freud gave up the claim of reintegrating psychological knowledge into the neuroscientific field for now. But up to his latest work he always adheres to the principal project of unifying the natural and the psychical being of the subject. In the gap between the two spheres, for long occupied by the discursive figure of the 'psycho-physical parallelism', Freud situated the Unconscious. In the passage to a psychoanalytical theory of psychic events Freud took up the model of the reflex arc well known from neurology. The transmission into psychoanalysis complexifies the unilinearity of reflexes, so that the psychic apparatus can be analysed as a cybernetic mechanism 'avant la lettre'. It is interesting enough that inhibition as well as consciousness play a key role in the regulation of the psychic apparatus. In this context Freud stresses the importance of speech and language within the

  6. Development of a novel solvent for the simultaneous separation of strontium and cesium from dissolved Spent Nuclear Fuel solutions

    International Nuclear Information System (INIS)

    Catherine L. Riddle; John D. Baker; Jack D. Law; Christopher A. McGrath; David H. Meikrantz; Bruce J. Mincher; Dean R. Peterman; Terry A. Todd

    2004-01-01

    The recovery of Cs and Sr from acidic solutions by solvent extraction has been investigated. The goal of this project was to develop an extraction process to remove Cs and Sr from high-level waste in an effort to reduce the heat loading in storage. Solvents for the extraction of Cs and Sr separately have been used on both caustic and acidic spent nuclear fuel waste in the past. The objective of this research was to find a suitable solvent for the extraction of both Cs and Sr simultaneously from acidic nitrate media. The solvents selected for this research possess good stability and extraction behavior when mixed together. The extraction experiments were performed with 4,4,(5)-Di-(tbutyldicyclohexano)-18-crown-6 (DtBuCH18C6), Calix[4]arene-bis-(tert-octylbenzocrown-6) (BOBCalixC6) and 1-(2,2,3,3-tetrafluoropropoxy)-3-(4-sec-butylphenoxy)-2-propanol (Cs-7SB modifier) in a branched aliphatic kerosene (Isopar L). The BOBCalixC6 and Cs-7SB modifier were developed at Oak Ridge National Laboratory (ORNL) by Bonnesen et al. [1]. The values obtained from the SREX solvent for DSr in 1 M nitric acid ranged from 0.7 to 2.2 at 25 C and 10 C respectively. The values for DCs in 1 M nitric acid with the CSSX solvent ranged from 8.0 to 46.0 at 25 C and 10 C respectively. A new mixed solvent, developed at the Idaho National Engineering and Environmental Laboratory (INEEL) by Riddle et al. [2], showed distributions for Sr ranging from 8.8 to 17.4 in 1 M nitric acid at 25 C and 10 C respectively. The DCs for the mixed solvent ranged from 7.7 to 20.2 in 1 M nitric acid at 25 C to 10 C respectively. The unexpectedly high distributions for Sr at both 25 C and 10 C show a synergy in the mixed solvent. The DCs, although lower than with CSSX solvent, still showed good extraction behavior

  7. A Resolution of the Paradox of Enrichment

    Science.gov (United States)

    Feng, Z. C.; Li, Y. Charles

    2015-06-01

    The paradox of enrichment was observed by Rosenzweig [1971] in a class of predator-prey models. Two of the parameters in the models are crucial for the paradox. These two parameters are the prey's carrying capacity and prey's half-saturation for predation. Intuitively, increasing the carrying capacity due to enrichment of the prey's environment should lead to a more stable predator-prey system. Analytically, it turns out that increasing the carrying capacity always leads to an unstable predator-prey system that is susceptible to extinction from environmental random perturbations. This is the so-called paradox of enrichment. Our resolution here rests upon a closer investigation on a dimensionless number H formed from the carrying capacity and the prey's half-saturation. By recasting the models into dimensionless forms, the models are in fact governed by a few dimensionless numbers including H. The effects of the two parameters: carrying capacity and half-saturation are incorporated into the number H. In fact, increasing the carrying capacity is equivalent (i.e. has the same effect on H) to decreasing the half-saturation which implies more aggressive predation. Since there is no paradox between more aggressive predation and instability of the predator-prey system, the paradox of enrichment is resolved. The so-called instability of the predator-prey system is characterized by the existence of a stable limit cycle in the phase plane, which gets closer and closer to the predator axis and prey axis. Due to random environmental perturbations, this can lead to extinction. We also further explore spatially dependent models for which the phase space is infinite-dimensional. The spatially independent limit cycle which is generated by a Hopf bifurcation from an unstable steady state, is linearly stable in the infinite-dimensional phase space. Numerical simulations indicate that the basin of attraction of the limit cycle is riddled. This shows that spatial perturbations can

  8. [Lessons from Guam ALS/PDC study].

    Science.gov (United States)

    Asao, Hirano

    2007-11-01

    no new treatment is available. Guam ALS/PDC is certainly one of the most mysterious riddles among age-associated neurodegenerative diseases during the last half a century.

  9. Notes on the Bull shark Carcharhinus leucas in the lagoon region of Cananéia, Brazil

    Directory of Open Access Journals (Sweden)

    V Sadowsky

    1971-12-01

    Full Text Available Ninety one young specimens and 3 adult females of BulI shark ("cação cabeça chata" caught in the lagoon region of Cananéia were examined, their tooth formula being 27/25 and the number of pre-caudal vertebrae ranging from 109 to 115. The proportion between the 1st and 2nd dorsal fins were found to be 2.3 and 2.8 for the young,and 2.9 to 3.1 for the adults. These data confirm that the studied form belongs to C. leuoas. Young occur regularly but in limited numbers.As regards the adults, however, females only appear during the short parturition period, i.e., from November to February. The number of embryos in the litters were from 7 to 9, their sizes ranging between 768-812 mm. The length of the smallest free young found was 697 mm, but young presumably 9 to 12 months old had 98 to 112 cm; between 21 and 24 months they were reaching 124 to 128 cm, that is, the same size they have when they start migrating to the open sea. The feeding inhibition phenomenon during the period of parturition was not observed in the female specimens caught in the lagoon. The more abundant species found in the stomach contents were: Arius spixii; Chloroscombrus chrysurus; A. grandicassus; A. barbus; Felichtys marinus; Genidens genidens; Chanophorus tajacica and Carcharhinus porosus.Noventa e um espécimes jovens e 3 fêmeas adultas de "cação cabeça chata" capturados na região lagunar de Cananeia foram examinados, constatando-se a fórmula dental 27/25 e número de vértebras pré-caudais entre 109 e 115.Verificouse que as proporções entre a la. nadadeira dorsal e a 2a. foram de 2.3 e 2.8 para os jovens e de 2.9 até 3.1 para os adultos.Ficou assim confirmado que a forma es tudada pertence a C. leuaas. É comum a ocorrência de jovens dentro da região estudada~ no entanto,quanto aos adultos,as fêmeas só são encontradas durante o período de parição, i.é, de novembro a fevereiro. Constatou-se que o número de embriões nas ninhadas foi de 7 a 9 e seus

  10. LHC Higgs physics beyond the Standard Model

    International Nuclear Information System (INIS)

    Spannowsky, M.

    2007-01-01

    The Large Hadron Collider (LHC) at CERN will be able to perform proton collisions at a much higher center-of-mass energy and luminosity than any other collider. Its main purpose is to detect the Higgs boson, the last unobserved particle of the Standard Model, explaining the riddle of the origin of mass. Studies have shown, that for the whole allowed region of the Higgs mass processes exist to detect the Higgs at the LHC. However, the Standard Model cannot be a theory of everything and is not able to provide a complete understanding of physics. It is at most an effective theory up to a presently unknown energy scale. Hence, extensions of the Standard Model are necessary which can affect the Higgs-boson signals. We discuss these effects in two popular extensions of the Standard Model: the Minimal Supersymmetric Standard Model (MSSM) and the Standard Model with four generations (SM4G). Constraints on these models come predominantly from flavor physics and electroweak precision measurements. We show, that the SM4G is still viable and that a fourth generation has strong impact on decay and production processes of the Higgs boson. Furthermore, we study the charged Higgs boson in the MSSM, yielding a clear signal for physics beyond the Standard Model. For small tan β in minimal flavor violation (MFV) no processes for the detection of a charged Higgs boson do exist at the LHC. However, MFV is just motivated by the experimental agreement of results from flavor physics with Standard Model predictions, but not by any basic theoretical consideration. In this thesis, we calculate charged Higgs boson production cross sections beyond the assumption of MFV, where a large number of free parameters is present in the MSSM. We find that the soft-breaking parameters which enhance the charged-Higgs boson production most are just bound to large values, e.g. by rare B-meson decays. Although the charged-Higgs boson cross sections beyond MFV turn out to be sizeable, only a detailed

  11. Negotiating the terrain of high-stakes accountability in science teaching

    Science.gov (United States)

    Aronson, Isaak

    Teachers interact with their students on behalf of the entire educational system. The aim of this study is to explore how biology teachers understand and construct their practice in a high-stakes accountability environment that is likely to be riddled with tensions. By critically questioning the technical paradigms of accountability this study challenges the fundamental assumptions of accountability. Such a critical approach may help teachers develop empowerment strategies that can free them from the de-skilling effects of the educational accountability system. This interpretive case study of a high-school in Maryland is grounded in three streams of research literature: quality science instruction based on scientific inquiry, the effects of educational accountability on the curriculum, and the influence of policy on classroom practice with a specific focus on how teachers balance competing tensions. This study theoretically occurs at the intersection of educational accountability and pedagogy. In terms of data collection, I conduct two interviews with all six biology teachers in the school. I observe each teacher for at least fifteen class periods. I review high-stakes accountability policy documents from the federal, state, and district levels of the education system. Three themes emerge from the research. The first theme, "re-defining science teaching," captures how deeply accountability structures have penetrated the science curriculum. The second theme, "the pressure mounts," explores how high-stakes accountability in science has increased the stress placed on teachers. The third theme, "teaching-in-between," explores how teachers compromise between accountability mandates and their own understandings of quality teaching. Together, the three themes shed light on the current high-stakes climate in which teachers currently work. This study's findings inform the myriad paradoxes at all levels of the educational system. As Congress and advocacy groups battle over

  12. Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene

    Directory of Open Access Journals (Sweden)

    Herington Adrian C

    2008-10-01

    Full Text Available Abstract Background The peptide hormone ghrelin has many important physiological and pathophysiological roles, including the stimulation of growth hormone (GH release, appetite regulation, gut motility and proliferation of cancer cells. We previously identified a gene on the opposite strand of the ghrelin gene, ghrelinOS (GHRLOS, which spans the promoter and untranslated regions of the ghrelin gene (GHRL. Here we further characterise GHRLOS. Results We have described GHRLOS mRNA isoforms that extend over 1.4 kb of the promoter region and 106 nucleotides of exon 4 of the ghrelin gene, GHRL. These GHRLOS transcripts initiate 4.8 kb downstream of the terminal exon 4 of GHRL and are present in the 3' untranslated exon of the adjacent gene TATDN2 (TatD DNase domain containing 2. Interestingly, we have also identified a putative non-coding TATDN2-GHRLOS chimaeric transcript, indicating that GHRLOS RNA biogenesis is extremely complex. Moreover, we have discovered that the 3' region of GHRLOS is also antisense, in a tail-to-tail fashion to a novel terminal exon of the neighbouring SEC13 gene, which is important in protein transport. Sequence analyses revealed that GHRLOS is riddled with stop codons, and that there is little nucleotide and amino-acid sequence conservation of the GHRLOS gene between vertebrates. The gene spans 44 kb on 3p25.3, is extensively spliced and harbours multiple variable exons. We have also investigated the expression of GHRLOS and found evidence of differential tissue expression. It is highly expressed in tissues which are emerging as major sites of non-coding RNA expression (the thymus, brain, and testis, as well as in the ovary and uterus. In contrast, very low levels were found in the stomach where sense, GHRL derived RNAs are highly expressed. Conclusion GHRLOS RNA transcripts display several distinctive features of non-coding (ncRNA genes, including 5' capping, polyadenylation, extensive splicing and short open reading

  13. The nature of the giant exomoon candidate Kepler-1625 b-i

    Science.gov (United States)

    Heller, René

    2018-02-01

    The recent announcement of a Neptune-sized exomoon candidate around the transiting Jupiter-sized object Kepler-1625 b could indicate the presence of a hitherto unknown kind of gas giant moon, if confirmed. Three transits of Kepler-1625 b have been observed, allowing estimates of the radii of both objects. Mass estimates, however, have not been backed up by radial velocity measurements of the host star. Here we investigate possible mass regimes of the transiting system that could produce the observed signatures and study them in the context of moon formation in the solar system, i.e., via impacts, capture, or in-situ accretion. The radius of Kepler-1625 b suggests it could be anything from a gas giant planet somewhat more massive than Saturn (0.4 MJup) to a brown dwarf (BD; up to 75 MJup) or even a very-low-mass star (VLMS; MJup ≈ 0.11 M⊙). The proposed companion would certainly have a planetary mass. Possible extreme scenarios range from a highly inflated Earth-mass gas satellite to an atmosphere-free water-rock companion of about 180 M⊕. Furthermore, the planet-moon dynamics during the transits suggest a total system mass of 17.6-12.6+19.2 MJup. A Neptune-mass exomoon around a giant planet or low-mass BD would not be compatible with the common mass scaling relation of the solar system moons about gas giants. The case of a mini-Neptune around a high-mass BD or a VLMS, however, would be located in a similar region of the satellite-to-host mass ratio diagram as Proxima b, the TRAPPIST-1 system, and LHS 1140 b. The capture of a Neptune-mass object around a 10 MJup planet during a close binary encounter is possible in principle. The ejected object, however, would have had to be a super-Earth object, raising further questions of how such a system could have formed. In summary, this exomoon candidate is barely compatible with established moon formation theories. If it can be validated as orbiting a super-Jovian planet, then it would pose an exquisite riddle for

  14. New Age of Exploration: A View from a Science Writer

    Science.gov (United States)

    Urban, Z.

    2012-09-01

    We present an auxiliary frame for planetary science outreach, based especially on historical parallels and analogues. The general aim is to create and further cultivate a broader public support for integrated planetary exploration (i.e., one which uses both interplanetary probes/orbital observatories and ground instruments). The main approach consist of a series of a quite limited units of information, consisting of a unifying background narration and short stories illustrating specific points. These units could come in two versions, one emphasizing the visual side (static photos, static drawings, animations, videos), something as movie-like trailers for a wide use, including their upload to YouTube, the other emphasizing the narration itself in voice or textual form. These presentations should be scientifically rigorous, both factually and contextually, but will make use of "showbusiness" and "marketing" features, in a better sense of these terms. Both versions will support interactiveness. The main point stressed is an extensive set of similarities between The Age of Exploration here on Earth (15th-19th century) on the one side and the present era of direct and indirect solar system exploration and a new dimension introduced by exoplanet discoveries on the other. The parallel/analogue approach is developed step by step, from early Portuguese explorers of the coast of West Africa (with mentions of ancient cases, represented, for example, by Phoenician and Greek colonisations of the Mediterranean. The consequences of the Age of Exploration benefited Europe enormously. The same could be expected form its modern space counterpart, as it has been demonstrated by a number of industrial outcomes from the Apollo Project. The relevant storytelling will highlight also mysteries and riddles (preserving sciece approach), like martian methane and probable ocean on Europa. The information units will be oriented towards the members of public, but keeping in mind psychology and

  15. Characterization of inclusions in terrestrial impact formed zircon: Constraining the formation conditions of Hadean zircon from Jack Hills, Western Australia

    Science.gov (United States)

    Faltys, J. P.; Wielicki, M. M.; Sizemore, T. M.

    2017-12-01

    Due to the discovery and subsequent geochemical analysis of Hadean terrestrial material (e.g. detrital zircon from Jack Hills, Western Australia), a dramatic paradigm shift has occurred in the hypothesized near surface conditions of the first 500 million years of Earth's evolution. From a hellish setting riddled with impactors and not fit for life to a much milder environment that may have been uniquely suitable for the origin of life. Geochemical analyses of these ancient materials have been used to suggest the presence of water at or near the surface as well as the existence of continental crust during the Hadean, both of which have been suggested as necessary for the origin of life. However, the intensity of extraterrestrial bombardment during the Hadean and the effects of such events on the origin of life remains poorly understood. Clearly, as evidenced by Phanerozoic impact events, extraterrestrial impactors have the potential to dramatically effect the environment, particularly the biosphere. Early Earth likely experienced multiple large impact events, as evidenced by the lunar record, however whether those impacts were sufficient to frustrate the origin of life remains an open question. Although multiple lines of evidence, including the inclusion population, suggest the formation of Hadean zircon from Jack Hills as crystallizing in an under-thrust environment from S-type magmas, a recent study has suggested their formation in an impact melt environment analogous to a portion of the Sudbury Igneous Complex at the Sudbury impact structure. To determine between these two formation scenarios we have under-taken an inclusion study of terrestrial impact formed zircon from four of the largest terrestrial impact structures (Sudbury, Canada; Manicouagan, Canada; Vredefort, South Africa; Morokweng, South Africa), to compare to the vast inclusion dataset that exists for Jack Hills zircon. Preliminary data suggests a different inclusion population, from Hadean zircon

  16. Application Development: AN Interactive, Non-Technical Perspective of the Geology and Geomorphology of the Ouray Perimeter Tail, CO.

    Science.gov (United States)

    Allen, H. M.; Giardino, J. R.

    2015-12-01

    Each year people seek respite from their busy lifestyles by traveling to state or national parks, national forests or wilderness areas. The majority of these parks were established in order to help preserve our natural heritage, including wildlife, forests, and the beauty of landscapes formed from thousands of years of geologic/geomorphologic processes. Whilst being able to enjoy the tranquility of nature, tourists are being robbed of a more in-depth experience as a result of the lack of a geologic background. One such location that attracts a large number of summer tourists is the perimeter trail in Ouray, Colorado. Located in the Southwestern portion of Colorado, Ouray is situated in the beautiful San Juan Mountain range along the "Million Dollar Highway." The Perimeter trail is a six-mile trail loop that circles the city of Ouray. The city is a very popular place for summertime tourism because of its unparalleled scenery. Ouray is situated in an area that is riddled with textbook angular unconformities, metasedimentary, sedimentary, and volcanic rocks. In the study area, The San Juans have been beautifully sculpted by an array of major faulting events, glacial activity and volcanics. With the understanding that technology is ever expanding, we think there is no better way to experience the Perimeter Trail than to have an interactive application that will be both educational as well as interesting. This application is a non-technical way of looking at the geology and geomorphology of the perimeter trail. Additionally, a paper brochure shows the most noteworthy points of interest. The brochure contains a brief geologic history of the San Juan Mountains accompanied with annotated photographs to illustrate the complex geology/geomorphology encountered on the trail. The application is based on an interactive three-dimensional map, which can be zoomed to various scales. The app hosts a locational service that uses the phone's GPS to communicate location of the hiker

  17. LHC Higgs physics beyond the Standard Model

    Energy Technology Data Exchange (ETDEWEB)

    Spannowsky, M.

    2007-09-22

    The Large Hadron Collider (LHC) at CERN will be able to perform proton collisions at a much higher center-of-mass energy and luminosity than any other collider. Its main purpose is to detect the Higgs boson, the last unobserved particle of the Standard Model, explaining the riddle of the origin of mass. Studies have shown, that for the whole allowed region of the Higgs mass processes exist to detect the Higgs at the LHC. However, the Standard Model cannot be a theory of everything and is not able to provide a complete understanding of physics. It is at most an effective theory up to a presently unknown energy scale. Hence, extensions of the Standard Model are necessary which can affect the Higgs-boson signals. We discuss these effects in two popular extensions of the Standard Model: the Minimal Supersymmetric Standard Model (MSSM) and the Standard Model with four generations (SM4G). Constraints on these models come predominantly from flavor physics and electroweak precision measurements. We show, that the SM4G is still viable and that a fourth generation has strong impact on decay and production processes of the Higgs boson. Furthermore, we study the charged Higgs boson in the MSSM, yielding a clear signal for physics beyond the Standard Model. For small tan {beta} in minimal flavor violation (MFV) no processes for the detection of a charged Higgs boson do exist at the LHC. However, MFV is just motivated by the experimental agreement of results from flavor physics with Standard Model predictions, but not by any basic theoretical consideration. In this thesis, we calculate charged Higgs boson production cross sections beyond the assumption of MFV, where a large number of free parameters is present in the MSSM. We find that the soft-breaking parameters which enhance the charged-Higgs boson production most are just bound to large values, e.g. by rare B-meson decays. Although the charged-Higgs boson cross sections beyond MFV turn out to be sizeable, only a detailed

  18. From Healthcare to Health: An Update of Norman Daniels’s Approach to Justice

    Directory of Open Access Journals (Sweden)

    Daniel Skinner

    2014-04-01

    Full Text Available Here is a health policy riddle: despite the fact that we are not always clear as to what we are trying to achieve, even on the most basic level, we must make policy anyway. Odder still: this is as we might expect it to be, and perhaps even as it should be. After all, part of what makes health policy important is precisely the fact that it raises critical questions about our most basic human values and social commitments. The conversation should be fluid. Norman Daniels has long been an important participant in these conversations. Just Health: Meeting Health Needs Fairly—a titular play on his 1985 book, Just Health Care (1—is Daniels’s attempt to wrestle with contemporary challenges that have forced him to rethink his positions. At its most basic level, then, Just Health can be read as a reminder of the tentativeness of scholarly positions on the core questions of health as well as the importance of being willing to revise both the questions we ask and the positions we take. In Just Health care, Daniels identified six important areas of concern: 1. Adequate nutrition, 2. Sanitary, safe, unpolluted living and working conditions, 3. Exercise, rest, and such important lifestyle features as avoiding substance abuse and practicing safe sex, 4. Preventive, curative, rehabilitative, and compensatory personal medical services (and devices, and 5. Nonmedical personal and social support services (pp. 42–3. Just Health adds a sixth critical component: other social determinants of health. To get to this level, Daniels uses early chapters to establish the “special moral importance of health” as an object of inquiry (Chapter 2, and to look beyond healthcare to a more-inclusive and socially-expansive view of health (Chapter 3. As Daniels notes, “bioethics has not looked ‘upstream’ from the point of delivery of medical services to the role of the healthcare system in improving population health.” As a result, it tends to miss

  19. Reducing supply chain energy use in next-generation vehicle lightweighting

    Energy Technology Data Exchange (ETDEWEB)

    Hanes, Rebecca J.; Das, Sujit; Carpenter, Alberta

    2016-09-29

    equipment is upgraded to the most efficient available. Preliminary analyses indicate that producing CF from lignin instead of polyacrylonitrile, the most commonly used feedstock, reduces energy consumption in the CFRP supply chain by 7.5%, and that implementing energy efficient process equipment produces an additional 8% reduction. Final results will show if these potential reductions are sufficient to make the CFV energy savings comparable with AIV energy savings. [1] Das, S., Graziano, D., Upadhyayula, V. K., Masanet, E., Riddle, M., & Cresko, J. (2016). Vehicle lightweighting energy use impacts in US light-duty vehicle fleet. Sustainable Materials and Technologies, 8, 5-13.

  20. LOS ALAMOS: Candidate events in a search for neutrino oscillations

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    In the past several years, a number of experiments have searched for neutrino oscillations,where a neutrino of one type (say muon-antineutrinos) spontaneously transforms into a neutrino of another type (say electron antineutrinos). For this phenomenon to occur, neutrinos must be massive and the apparent conservation law of lepton families must be violated. At this time, there is no broadly accepted evidence for neutrino oscillations from a terrestrial experiment. The Liquid Scintillator Neutrino Detector (LSND) experiment (July 1993, page 10) at the Los Alamos Meson Physics facility (LAMPF) is designed to search with high sensitivity for muon-antineutrino electronantineutrino oscillations from positive muon decay at rest. The collaboration consists of groups from the University of California at Riverside, San Diego and Santa Barbara, the University California Intercampus Institute for Research at Particle Accelerators, Embry Riddle Aeronautical University, Linfield College, Los Alamos National Laboratory, Louisiana State University, Louisiana Tech University, the University of New Mexico, Southern University, and Temple University. LAMPF is an intense source of low energy neutrinos due to its 1 mA proton intensity and 800 MeV energy. The neutrino source is well understood because almost all neutrinos arise from positive pion or muon decay; negative muons and pions are readily captured in the iron of the shielding and copper of the beam stop. The production of kaons and heavier mesons is negligible at these energies. The electron-antineutrino rate is calculated to be only 4 x 10 -4 that of muon-antineutrinos in the neutrino energy range between 36 and 52.8 MeV, so that the observation of a significant electronantineutrino rate would be evidence for muon-antineutrino electronantineutrino oscillations. The LSND detector consists of an approximately cylindrical tank 8.3 m long by 5.7 m in diameter. The centre of the detector is 30 m from the neutrino source. On the

  1. The Marxist Aspect in Bessie Head's A Question of Power

    Directory of Open Access Journals (Sweden)

    Mohamed Fathi Helaly

    2016-11-01

    Full Text Available South Africa is one country where racial discrimination was widespread. Like the rest of the color-skinned people, colored writers in South Africa are marginalized and denied the right to express their experiences of living in a society riddled with racial inequality and oppression. Marxism is a school of thought that is concerned about the conflict between the dominant powerful classes and the oppressed ones in any given society. According to Marxism, literary texts are viewed as material that can be interpreted within historical contexts. South Africa is a country where the Apartheid System has been dominant. It is a country that has people of different ethnicity: the White, the Black and the Colored who are known as people of mixed race or hybrid. In South Africa colored people are doubly oppressed by their community, as they belong neither to the Black nor to the White. The colored people are marginalized and demeaned to a very degraded status by their society. Bessie Head is a South African female writer who is concerned about the clash between the different classes in her society. In this study the researcher wants to explore the class-struggle of women in general and the hybrid females in particular under the Apartheid System from a Marxist point of view. As a South-African female writer, Head is concerned about the struggle for power between the White and The Black, on the one hand, and between the hybrids on the other. A Question of Power can be seen as an indictment of the governing system in South Africa. It is a system that governs people not as ordinary human beings but according to the color of their skin. It is an autobiographical novel that tells the story of Elizabeth as a women living under the Apartheid System. Elizabeth, the fictional character of Bessie Head, has to suffer greatly as a woman but her suffering as a hybrid is even greater. On the one hand, she is socially marginalized as a female living in a patriarchal

  2. News reports: update on buying indoor UV tanning with university debit cards.

    Science.gov (United States)

    Goff, Kiera L; Karimkhani, Chante; Boyers, Lindsay N; Hernandez, Melia D; Pederson, Hannah; Royer, Eryn L; Dellavalle, Robert P

    2014-12-13

    Indoor tanning by adults under 35 years of age increases the risk of developing melanoma 59% to 75%. Cost is a major barrier limiting young adults from purchasing indoor tanning services. Our recent study by Boyers et al determined that 18 of 96 major universities, all in the eastern and southern United States, had university-sponsored debit cards with indoor tanning affiliations. These debit cards, which conveniently link with student identification (ID) cards, help with student living expenses and are often loaded with money by parents. By creating agreements with indoor tanning salon vendors, universities are endorsing a World Health Organization class I carcinogen. To expand the results of our previous study, we broadened our search to further assess universities in the western United States as well as Australia, New Zealand, Ireland, Canada, and the United Kingdom. Using www.collegeboard.edu, we identified the 4 largest residential colleges in Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming. Additionally, we investigated the top international universities, utilizing www.topuniversities.com. Internet searches, phone calls, and email correspondence were used to determine if an institution had a student ID-linked debit card. Universities with affiliations to bank debit cards and cards that could only be used on campus were excluded. In the western United States, indoor tanning merchants were affiliated with University of Arizona, Embry-Riddle Aeronautical University: Prescott Campus, and the University of Denver student debit cards. Of the original 18 schools with affiliations according to the Boyers et al study, 2 universities no longer have agreements and 5 created agreements with additional tanning salons. Of 45 universities examined in our international search, no debit cards were discovered for off-campus purchases. Therefore, the concerning issue of university associations with tanning salons appears

  3. Spectroscopy of electronic transitions in Polycyclic Aromatic Hydrocarbon cations and their clusters

    International Nuclear Information System (INIS)

    Friha, Hela

    2012-01-01

    This thesis is an experimental study of the electronic spectroscopy of cations of Polycyclic Aromatic Hydrocarbons (PAHs) and their aggregates in conditions close to those of the interstellar medium (ISM), i.e. cold and totally isolated in the gas phase. It is related to the astrophysical context of the interstellar medium (ISM), in particular on the question of the possible link between interstellar PAHs and Diffuse Interstellar Bands (DIBs). The purpose of this thesis is to provide laboratory spectra which can be directly compared to the spectra of DIBs. Indeed these bands are the oldest spectroscopy riddle in astrophysics which remained unanswered for nearly 100 years and whose key is still looked for. A special attention is given to the methylated derivatives of PAHs species detected in many interstellar environments, cationic PAH dimers (the simplest PAH clusters). These clusters have been proposed as a model of the very small grains, which contribute to the formation of interstellar PAHs and whose chemical composition remains uncertain. This thesis has been mainly devoted to the determination of the electronic spectra of naphthalene cation monomer (Np + ) and its methylated derivative (2-MeN p + ), as well as the associated homogeneous dimers. The experimental method used is based on the photodissociation of van der Waals complexes PAH + m -Ar n (argon atoms spectators), prepared by UV laser photoionization in a supersonic jet. This technique combines different experimental tools, namely: molecular beam mass spectrometry and laser spectroscopy as well as physical tools such as the handling of clusters VdW PAH + m -Ar n , the detection of photo-fragments, the measurement of photodissociation efficiency. The identification of the fragments by the photodissociation of VdW clusters allowed us to determine the different possible fragmentation channels and especially to obtain the spectra the charge resonance transition and the first allowed transition to locally

  4. The Epidemiology of Operation Stress during Continuing Promise 2011: A Humanitarian Response and Disaster Relief Mission aboard a US Navy Hospital Ship.

    Science.gov (United States)

    Scouten, William T; Mehalick, Melissa L; Yoder, Elizabeth; McCoy, Andrea; Brannock, Tracy; Riddle, Mark S

    2017-08-01

    /MH complaints increased as the mission progressed, were more prevalent in certain groups, and appeared to be related to ship's movement. These findings document the pattern of operational stress in a ship-based medical humanitarian mission and confirm unique ship-based stressors. This information may be used by planners of similar missions to develop mitigation strategies for known stressors and by preventive medicine, behavioral health specialists, and mission leaders to develop sensitive surveillance tools to better detect and manage operational stress while on mission. Scouten WT , Mehalick ML , Yoder E , McCoy A , Brannock T , Riddle MS . The epidemiology of operation stress during Continuing Promise 2011: a humanitarian response and disaster relief mission aboard a US Navy hospital ship. Prehosp Disaster Med. 2017;32(4):393-402.

  5. Future coal production outlooks in the IPCC Emission Scenarios: Are they plausible?

    International Nuclear Information System (INIS)

    Hoeoek, Mikael

    2010-10-01

    Anthropogenic climate change caused by CO 2 emissions is strongly and fundamentally linked to the future energy production. The Special Report on Emission Scenarios (SRES) from 2000 contains 40 scenarios for future fossil fuel production and is used by the IPCC to assess future climate change. Coal, with its 26% share of world energy, is a major source of greenhouse gas emissions and commonly seen as a key contributor to anthropogenic climate change. SRES contains a wide array of different coal production outlooks, ranging from a complete coal phase-out by 2100 to a roughly tenfold increase from present world production levels. Scenarios with high levels of global warming also have high expectations on future fossil fuel production. The assumptions on resource availability are in SRES based on Rogner's assessment of world hydrocarbon resources from 1997, where it is stated that 'the sheer size of the fossil resource base makes fossil sources an energy supply option for many centuries to come'. Regarding the future coal production it is simply assumed to be dependent on economics, accessibility, and environmental acceptance. It is also generally assumed that coal is abundant, and will thus take a dominating part in the future energy system. Depletion, geographical location and geological parameters are not given much influence in the scenario storylines. This study quantifies what the coal production projection in SRES would imply in reality. SRES is riddled with future production projections that would put unreasonable expectation on just a few countries or regions. Is it reasonable to expect that China, among the world's largest coal reserve and resource holder and producer, would increase their production by a factor of 8 over the next 90 years, as implied by certain scenarios? Can massive increases in global coal output really be justified from historical trends or will reality rule out some production outlooks as implausible? The fundamental assumptions

  6. Future coal production outlooks in the IPCC Emission Scenarios: Are they plausible?

    Energy Technology Data Exchange (ETDEWEB)

    Hoeoek, Mikael

    2010-10-15

    Anthropogenic climate change caused by CO{sub 2} emissions is strongly and fundamentally linked to the future energy production. The Special Report on Emission Scenarios (SRES) from 2000 contains 40 scenarios for future fossil fuel production and is used by the IPCC to assess future climate change. Coal, with its 26% share of world energy, is a major source of greenhouse gas emissions and commonly seen as a key contributor to anthropogenic climate change. SRES contains a wide array of different coal production outlooks, ranging from a complete coal phase-out by 2100 to a roughly tenfold increase from present world production levels. Scenarios with high levels of global warming also have high expectations on future fossil fuel production. The assumptions on resource availability are in SRES based on Rogner's assessment of world hydrocarbon resources from 1997, where it is stated that 'the sheer size of the fossil resource base makes fossil sources an energy supply option for many centuries to come'. Regarding the future coal production it is simply assumed to be dependent on economics, accessibility, and environmental acceptance. It is also generally assumed that coal is abundant, and will thus take a dominating part in the future energy system. Depletion, geographical location and geological parameters are not given much influence in the scenario storylines. This study quantifies what the coal production projection in SRES would imply in reality. SRES is riddled with future production projections that would put unreasonable expectation on just a few countries or regions. Is it reasonable to expect that China, among the world's largest coal reserve and resource holder and producer, would increase their production by a factor of 8 over the next 90 years, as implied by certain scenarios? Can massive increases in global coal output really be justified from historical trends or will reality rule out some production outlooks as implausible? The

  7. The Principle of the Eternal-Feminine in Rossini’s L’Italiana in Algeri: Isabella as the Italian Super-Woman

    Directory of Open Access Journals (Sweden)

    Zamir, Sara

    2011-12-01

    Full Text Available The term Eternal-Feminine, or Das Ewig-Weibliche, first appeared in the last verses of the second part of Goethe’s Faust (completed 1832. It, subsequently, became the subject of speculation and a riddle which scholars have been trying to solve ever since. The term gradually came to represent a cultural principle regarding the image of femininity and it reached its Romantic apex, in the 19th Century, when various female archetypes were fused into a singe heroine. The present article aims to explore Isabella’s character in Rossini’s L’Italiana in Algeri in the light of the principle of the Eternal-Feminine. Although Goethe was still in the process of writing the second part of Faust when L’Italiana premiered (1813 in Italy, the cultural principle of the Eternal- Feminine can be used retrospectively in the analysis of Isabella as the central female protagonist of the opera. A thorough reading of her character suggests an aesthetic approach that makes use of certain Romantic aspects of the Eternal-Feminine principle. The present article focuses specifi cally on the Cruda sorte! Amor tiranno! scene and briefl y refers to other scenes as well.La expresión Eterno Femenino (Eternal-Feminine, o Das Ewig-Weibliche, apareció por primera vez en los últimos versos de la segunda parte del Fausto de Goethe (acabado en 1832. Posteriormente, se convirtió en tema de especulación, y en un enigma que los estudiosos han estado intentando resolver desde entonces. La expresión vino a identificar, con el paso del tiempo, un principio cultural relacionado con la imagen de la feminidad y alcanzó su extremo romántico, en el siglo XIX, cuando diversos arquetipos femeninos se fundieron en una sola heroína. El presente artículo pretende explorar el personaje de Isabella en La italianaen Argel de Rossini, a la luz del principio del Eterno Femenino. Aunque Goethe se encontraba todavía escribiendo la segunda parte de su Fausto cuando se estrenó La italiana

  8. A multiple-proxy approach to understanding rapid Holocene climate change in Southeast Greenland

    Science.gov (United States)

    Davin, S. H.; Bradley, R. S.; Balascio, N. L.; de Wet, G.

    2012-12-01

    The susceptibility of the Arctic to climate change has made it an excellent workshop for paleoclimatological research. Although there have been previous studies concerning climate variability carried out in the Arctic, there remains a critical dearth of knowledge due the limited number of high-resolution Holocene climate-proxy records available from this region. This gap skews our understanding of observed and predicted climate change, and fuels uncertainty both in the realms of science and policy. This study takes a comprehensive approach to tracking Holocene climate variability in the vicinity of Tasiilaq, Southeast Greenland using a ~5.6 m sediment core from Lower Sermilik Lake. An age-depth model for the core has been established using 8 radiocarbon dates, the oldest of which was taken at 4 m down core and has been been dated to approximately 6.2 kyr BP. The bottom meter of the core below the final radiocarbon date contains a transition from cobbles and coarse sand to organic-rich laminations, indicating the termination of direct glacial influence and therefore likely marking the end of the last glacial period in this region. The remainder of the core is similarly organic-rich, with light-to-dark brown laminations ranging from 0.5 -1 cm in thickness and riddled with turbidites. Using this core in tandem with findings from an on-site assessment of the geomorphic history of the locale we attempt to assess and infer the rapid climatic shifts associated with the Holocene on a sub-centennial scale. Such changes include the termination of the last glacial period, the Mid-Holocene Climatic Optimum, the Neoglacial Period, the Medieval Climatic Optimum, and the Little Ice Age. A multiple proxy approach including magnetic susceptibility, bulk organic geochemistry, elemental profiles acquired by XRF scanning, grain-size, and spectral data will be used to characterize the sediment and infer paleoclimate conditions. Additionally, percent biogenic silica by weight has been

  9. El Jordán que ha de purificarnos: La reforma educativa de Germán Gamazo en 1898

    Directory of Open Access Journals (Sweden)

    González de Pablo, Ángel

    1999-12-01

    Full Text Available The colonial defeat in the summer of 1898 unleashed a strong urge for deep educational changes in Spanish public opinion, as the shortages in this field were considered one of essential causes of the Disaster. Germán Gamazo, the Developement minister at that time, undertook this demand and promulgated several hasty decrees riddled with deficiencies in September and October of that year. Nevertheless, the response to them was at first very favourable due to the yearning for regeneration that existed in the Spanish society. Only from the first week of October onwards did criticisms, until then very limited, increase considerably, becoming even severer in the third week when several cases of corruption, which stained the reform, were published. That situation finally led Gamazo to resign at the end of that month and wrecked his reform shortly after. This paper analyses the various motives behind Gamazo's reform, its reception in the diverse types of press (professional, political, conservative, liberal or independent, the reasons for its lack of success and the consequences that resulted from this failure.

    La derrota colonial del verano de 1898 desató un enorme afán de renovación pedagógica en la opinión pública española, al ser consideradas las deficiencias en este campo una de las causas esenciales del Desastre. El entonces ministro de Fomento, Germán Gamazo, recogió esa demanda y emprendió, en septiembre de ese año, una precipitada reforma mediante una serie de reales decretos que adolecían de numerosas incoherencias. A pesar de ello, su acogida fue en un principio, debido a ese anhelo de regeneración de que estaba saturado el ambiente social, muy favorable. Sólo en la primera semana de octubre, las críticas, hasta entonces puntuales, comenzaron a generalizarse, tomándose todavía más acerbas cuando, a partir de la tercera semana, se comenzaron a publicar algunas de las corruptelas que acompañaban a la reforma

  10. Constitutive mass balance relations between chemical composition, volume, density, porosity, and strain in metasomatic hydrochemical systems: Results on weathering and pedogenesis

    Science.gov (United States)

    Brimhall, George H.; Dietrich, William E.

    1987-03-01

    Relations characterizing the chemical, physical, and mechanical changes resulting from metasomatic hydrochemical processes are developed using mass balance models which formally link chemical composition to bulk density, mineral density, volumetric properties, porosity, and amount of deformation (strain). Rigorous analysis of aqueous solute transport effects is then made possible in a variety of porous media flow environments including chemical weathering, pedogenesis (soil formation), diagenesis, ore deposition and enrichment, and metamorphism. Application of these linear constitutive relations to chemical weathering profiles shows that immobile and locally mobile chemical elements, with masses conserved on the scale of soil profiles, can be accurately identified from analysis of appropriate data arrays and then used as natural geochemical tracers to infer the nature and extent of hydrochemical weathering processes and volume changes during pedogenesis. Assumptions commonly made in the past about the supposed immobility of certain elements, e.g., Ti and Zr, become unnecessary. Quantitative differentiation between the effects of residual and supergene fractionation is then easily made. These methods are applied to Ni-rich laterites developed by weathering of ultramafic rocks, showing that during ordinary residual enrichment, Ni is concentrated by as much as 4× protolith peridotite concentrations. This occurs simply by silicate mineral dissolution and removal of chemical elements other than Ni ( e.g., Mg) with a corresponding reduction in saprolite density and increase in bulk porosity without significant deformation. In contrast, laterites with mineable concentrations of Ni which are similarly undeformed (such as the Nickel Mountain Mine in Riddle, Oregon) have experienced, in addition to residual enrichment, strong supergene enrichment by fractionation of ore elements between a leached zone from which Ni is extracted and a complementary enriched zone positioned

  11. Forest and Society: Initiating a Southeast Asia Journal for Theoretical, Empirical, and Regional Scholarship

    Directory of Open Access Journals (Sweden)

    Micah Fisher

    2017-04-01

    Full Text Available Welcome to our first edition. We are excited to provide a new, and what we believe, timely avenue for presenting research findings and publications in Southeast Asia, for scholars interested in Southeast Asia. Although Southeast Asia as a region of study has provided tremendous contributions to theory and practice regarding forests and society across the social and natural sciences, avenues for cultivating a scholarship of the region remain limited. We seek to engage on a broad set of themes through the application of targeted research related to timely issues affecting the human-environment interface in a diverse region that we have much to learn from. We take a broad understanding of the forest - as a politico-administrative unit, a geographic area, and as an ecological unit. We do not limit the forest to its boundaries but rather seek to engage on the dynamics of change in social and ecological processes. Under such an umbrella, new approaches and methods become possible. ‘Forest’ can be analyzed as land use, ecological process, divided across watersheds, as landscapes, mountains, and more. The lens of ‘society’ allows for opportunities to understand change, whether it is the interaction between a resource to be preserved, exploited, forgotten, or erased. Forests, therefore, operate as the clues of what once was, has become, and what can be. Particularly in the age of climate change, riddled by increasingly complex challenges, a new dimension also emerges for the forest. Different perspectives at different scales – from the local to the global – provide equally important dimensions, and are those which we seek to provide avenues to learn from, and communicate through this journal. As the reader will find in this inaugural issue, we have compiled an initial set of studies across multiple methods and geographies that help to set the terms of future editions. We examine: historical political ecologies of land use around opium

  12. A condição das mulheres no Islã: a questão da igualdade Islamic women's status: the question of equality

    Directory of Open Access Journals (Sweden)

    Aïcha El Hajjami

    2008-06-01

    Full Text Available No ocidente, o tema da condição das mulheres no Islã está ligado à representação que geralmente se faz do Islã e dos muçulmanos. É uma representação constituída por estereótipos, esquematizações reducionistas e por confusões conceituais. A realidade do Islã e das sociedades muçulmanas possui muito mais nuances e freqüentemente não corresponde às idéias estabelecidas. A condição de inferioridade e precariedade a que está confinada a maior parte das mulheres muçulmanas, revela principalmente a hegemonia de uma mentalidade e de um sistema patriarcal que instrumentaliza sua leitura da religião para legitimar as situações de dominação, de violência e de exclusão em relação às mulheres. Partindo desta constatação, a autora propõe uma outra leitura do Islã e uma reflexão sobre a noção de igualdade no Alcorão e Sunna, na sua relação com o contexto da revelação, as finalidades da Chari'a e as perspectivas de evolução que podem revelar o referencial islâmico. Este trabalho de base é passível de reduzir as distâncias entre os princípios de igualdade entre os sexos inscritos nas convenções internacionais e seu equivalente no Islã.The Western idea relative to Islamic women's status is linked to the representations generally held on Islam and Muslim people. These representantions are riddled by esterotypes, reductionist schemas and conceptual confusions. Islam and Muslim societies' reality is much more nuanced and common held ideas do not correspond to it. The inferior status and poverty in which most of Muslim women are confined show the hegemony of a mentality and a patriarchal system that uses its readings of religion in order to legitimate the domination, violence and exclusion of women. Beginning with this idea, the author proposes another reading of Islam and a reflection about the equality notions in the Coran and in the Sunna in the context of revelation, Chari'a objectives and the

  13. Incorporating the principles of the patient- centered medical home into a student-run free clinic

    Directory of Open Access Journals (Sweden)

    Riddle MC

    2014-09-01

    Full Text Available Megan C Riddle,1,* Jiahui Lin,3,* Jonathan B Steinman,2 Joshua D Salvi,2 Margaret M Reynolds,3 Anne S Kastor,3,† Christina Harris,4 Carla Boutin-Foster3 1Department of Psychiatry and Behavioral Sciences, University of Washington, 2Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD–PhD Program, 3Department of Internal Medicine, Weill Cornell Medical College, New York, NY, 4Department of Medicine, Division of General Internal Medicine, VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, LA, USA *These authors contributed equally to this work †Anne S Kastor passed away on July 5, 2013. Abstract: As the health care delivery landscape changes, medical schools must develop creative strategies for preparing future physicians to provide quality care in this new environment. Despite the growing prominence of the patient-centered medical home (PCMH as an effective model for health care delivery, few medical schools have integrated formal education on the PCMH into their curricula. Incorporating the PCMH model into medical school curricula is important to ensure that students have a comprehensive understanding of the different models of health care delivery and can operate effectively as physicians. The authors provide a detailed description of the process by which the Weill Cornell Community Clinic (WCCC, a student-run free clinic, has integrated PCMH principles into a service-learning initiative. The authors assessed patient demographics, diagnoses, and satisfaction along with student satisfaction. During the year after a PCMH model was adopted, 112 students and 19 licensed physicians volunteered their time. A review of the 174 patients seen from July 2011 to June 2012 found that the most common medical reasons for visits included management of hypertension, hyperlipidemia, diabetes, gastrointestinal conditions, arthritis, anxiety, and depression. During the year after the adoption of the PCMH model, 87

  14. From Corpus to Dictionary: A Hybrid Prescriptive, Descriptive and Proscriptive Undertaking Okulondoola engeli Eitu ly'Olusoga bwe Linaatuusibwa mu Iwanika: Omutindo ogulaga Olulimi bwe luli, bwe luteekwa okuba oba bwe lube lutwalibwe.

    Directory of Open Access Journals (Sweden)

    Minah Nabirye

    2012-01-01

    :

    Obufunze: Empandiika y'Olusoga ekaali inhuma inho waile nga waliwooku obubonelo obulaga enkola y'obuzila mu kugizimba. Olusoga lukaawagamiile wansi w'ennimi nga Oluganda n'olulimi olw'eiwanga, Olungeleza. Ensonga endala ku dhikaalemeisa Olusoga okwetengelela n'okuba nti lulina ebigambo ebilwingila buli olukeile. Eky'embi, enkyukakyuka ebigambo bino ebiyaaka by'eleetawo eli kwidha mu kiseela nga Olusoga lwene lukaali kufunilwaku mpandiika ntongole. Waile walifu dh'Olusoga buti dhiliwo kamaala, wazila ndala ku dho eli kugobelelwa mu kuwandiika kubanga abantu bakaawandiika nga bwe babona. Ebiwandiiko ebili ku Lusoga oba mu lulimi Olusoga byetaagibwa okulaga Olusoga bwe lulina okuba ela n'ebilina okwebuuzibwaku. Eibula ly'ebiwandiiko oti ni bino litegeeza nti omunoonheleza alina okwefunila entambi dh'Olusoga olwogelwa ela yeewanulila Olusoga oluli mu ntambi edho okusobola okutegeela engeli olulimi olwo bwe luli mu kiseela ekyo. Kino kileeseewo obuzibu obundi nti Olusoga olwogelwa tilutongoze ate lulimu emigote kamaala egyandibaile gilondoolwa okusinziila ku mutindo omusengeke singa lubailem mu buwandiike. Ekika ky'Olusoga oluli mu mbeela eyogelwa kya ndhawulo ku kili mu mbeela y'obuwandiike. Okuwanula Olusoga okuva mu ntambi kw'aba nti kugiililiile kwagayaga na kunoga kibala kikaali kwenga bukalamu. Aye engeli ye kili nti Olusoga lulina aboogezi abaswika mu bukaile obubili, abanoonheleza ku Lusoga baalisaine kutandiika li? Olupapula luno lulambulula enzimba y'eitu ly'Olusoga nga ekitundutundu ky'eitu lino kiviile mu Lusoga olwawanulwa okuva mu mbeela eyogelwa. Obuzibu obwayagaanibwa mu mpandiika y'ebigambo ebyawanulwa n'obusimbiibwaku eisila. Okulaga engeli y'okuzigula obuzibu bw'empandiika mu isomo ly'amawanika kwetaagisa enkola eteekubila inho ku nsonga ndala aye enoonheleza engeli esinga kugasa omutendela gw'obuzibu obulondoolebwa. Waile nga obuzibu obundi busobola okugondhoolwa okugiila ku mutendela oguteebwawo, gwalaga olulimi nga bwe luteekwa okuba, obuzibu

  15. VADASE: a new approach for real-time fast displacement detection - First application to Taiwan High-Rate GNSS Network

    Science.gov (United States)

    Hung, Huang-Kai; Rau, Ruey-Juin; Colosimo, Gabriele; Benedetti, Elisa; Branzanti, Mara; Crespi, Mattia; Mazzoni, Augusto

    2014-05-01

    with very promising results to GPS single frequency data in occasion of the Emilia Earthquake (Italy, M=6.0 - May 20, 2012) [2] and also to Galileo single and dual frequency data [1]. VADASE, in principle, can be embedded into the receiver firmware and work in real-time. In this respect, at present, in the frame of an investigation project, VADASE has been implemented within the last release of the firmware of Leica Geosystems GR receivers. Here we present the application of the VADASE methodology to data collected at several permanent stations of Taiwan High-Rate GNSS Network in occasion of recent earthquakes occurred on June 2, 2013 (south-west of Buli, M=6.2, USGS) and October 31, 2013 (south-west of Hualian, M=6.3, USGS). Furthermore a solutions comparison with results obtained from co-located accelerometers and seismometers is shown and all the kinematic parameters are investigated. In particular, estimated velocities from VADASE are directly compared with seismometers dataset. Then, VADASE velocities are derived to perform a comparison with data collected by accelerometers. Finally, a comparison in terms of displacements obtained from all the instruments is carried out. With these tests a new strategy to integrate traditional seismic network with the information coming from GNSS data can be better assessed. [1] Benedetti E, Branzanti M, Colosimo G, Mazzoni A, Crespi M (2013). VADASE: state of the art and new developments of a third way to GNSS Seismology. International Association of Geodesy Symposia (Accepted for publication) [2] Benedetti E, Branzanti M, Biagi L, Colosimo G, Mazzoni A, Crespi M (2013). GNSS seismology for the 2012 Mw = 6.1 Emilia Earthquake: exploiting the VADASE algorithm. Seismological Research Letters (Accepted for publication) [3] Branzanti M, Colosimo G, Crespi M, Mazzoni A (2012) GPS near real-time coseismic displacements for the great Tohoku-Oki earthquake, doi:10.1109/LGRS.2012.2207704, IEEE Geoscience and Remote Sensing Letters [4

  16. [The influence of caregivers' anxiety and the home environment on child abuse. A study of children attending child-care centers].

    Science.gov (United States)

    Mochizuki, Yukiko; Tanaka, Emiko; Shinohara, Ryoji; Sugisawa, Yuka; Tomisaki, Etsuko; Watanabe, Taeko; Tokutake, Kentaro; Matsumoto, Misako; Sugita, Chihiro; Anme, Tokie

    2014-01-01

    were age and gender. We used multiple logistic regression to assess the actual child abuse predictors. The odds ratios obtained by comparing the "abused group" with the "non-abused group" showed that the caregivers of children in the "abused group" had a 5.5-fold greater odds of saying, "I am riddled with uneasiness and awful feelings," and a 4.6-fold greater odds of saying, "I do not have anyone to look after my child except a child-care center." The moderating variables (age and gender) were not significant. Child-care professionals have a policy for ensuring there is concrete and usable support for caregivers, depending on the relationship between the abused child and the difficulties present in the child's environment. We suggest that awareness of these relationships can be promoted as an aid for early child abuse detection, support, and prevention.

  17. The Lord of Rings - the mysterious case of the stolen rings: a critical analysis

    Science.gov (United States)

    Sandrelli, S.

    The Lord of Rings - the mysterious case of the stolen rings: a critical analysis S. Sandrelli INAF - Osservatorio Astronomico di Brera, Milano, Italy (stefano.sandrelli@brera.inaf.it / Fax: 02 72001600 / Phone: +39 02 72320337) "The Lord of Rings - the mysterious case of the stolen rings" is a live astronomical role-playing game for kids aged 10 -13. Its goal is to introduce them to some of the main topics of the Solar System: a) the role of gravity; b) the distribution of mass & light; c) the effects of rotation; d) the distribution of water. The game was held both at the Perugia (2004) and the Genova Science Festival (2005), obtaining great success. Teams of about 6-8 members are introduced to Mr Schioppanelli, the astro-detective of the town (the name is a pun: it reminds Schiaparelli, the famous italian astronomer, and it is a slang expression meaning "ring-breaker"). Mr Schioppanelli has his office in an "gastronomical astronomical observatory", known as The Red Giant Pizzeria. Schioppanelli informs the kids that a mysterious Centaur succeded in stealing the rings of Saturn. The partecipants are appointed astro-detectives in-charge and asked to find the rings by browsing around the Solar System, which is scaled so as to fit the town historical centre or a pedestrian area, going from the Sun to Saturn or beyond, depending on the actual area at disposal. Great care must be taken allowing children playing only in a car-free area of the town. At the right scaled distances, the partecipants meet characters playing as the various planets. The kids can talk to them after solving a riddle, obtaining useful informations. A special characters play as a comet, timely going in and out of the inner solar system. The teams can also talk to some shepherd-moons of the rings. They easily discover that the rings were totally destroyed by the Centaur: a real disaster! They are also suggested to gather the necessary ingredients (gravity, light, rotation, inclination, dust and

  18. BOOK REVIEW: Physics in the Real World

    Science.gov (United States)

    Jardine, Jim

    2000-05-01

    after stirring? I have a sense of déjà vu with this last question as it and others in this book were also discussed in the brilliantly written and illustrated volume Riddles in your Teacup, published by the Institute of Physics a few years ago. Miscellaneous. This section deals with topics such as quartz halogen lamps, degreening oranges, free-fall phenomena and a discussion on the origins of the terms `physics' and `physicist'. The concluding section is devoted exclusively to Rudolph the Red-nosed Reindeer and Santa Claus. It is clearly intended to convince readers that Physics is (still) Fun!

  19. Origin and annihilation physics of positrons in the Galaxy

    International Nuclear Information System (INIS)

    Alexis, Anthony

    2014-01-01

    A gamma radiation at 511 keV is observed since the early 1970's toward the Galactic bulge region. This emission is the signature of a large number of electron-positron annihilations, the positron being the electron's antiparticle. Unfortunately, the origin of the positrons responsible for this emission is still a mystery. Many positron-source candidates have been suggested but none of them can account for the galactic annihilation emission. The spatial distribution of this emission is indeed very atypical. Since 2002, the SPI spectrometer onboard the INTEGRAL space laboratory revealed an emission strongly concentrated toward the galactic bulge and a weaker emission from the galactic disk. This morphology is unusual because it does not correspond to any of the known galactic astrophysical-object or interstellar-matter distributions. The assumption that positrons annihilate close to their sources (i.e. the spatial distribution of the annihilation emission reflects the spatial distribution of the sources) has consequently been called into question. Recent studies suggest that positrons could propagate far away from their sources before annihilating. This physical aspect could be the key point to solve the riddle of the galactic positron origin. This thesis is devoted to the modelling of the propagation and annihilation of positrons in the Galaxy, in order to compare simulated spatial models of the annihilation emission with recent measurements provided by SPI/INTEGRAL. This method allows to put constraints on the origin of galactic positrons. We therefore developed a propagation Monte-Carlo code of positrons within the Galaxy in which we implemented all the theoretical and observational knowledge about positron physics (sources, transport modes, energy losses, annihilation modes) and the interstellar medium of our Galaxy (interstellar gas distributions, galactic magnetic fields, structures of the gaseous phases). Due to uncertainties in several physical parameters

  20. Utopia Planitia

    Science.gov (United States)

    2002-01-01

    (Released 15 May 2002) The Science This image is located in Utopia Planitia, a large plain in the northern hemisphere. It is believed that this basin is the result of a large impact. On the right side of the image is a partially imaged crater with a well-preserved ejecta blanket. The morphology of the ejecta implies that the crater is young relative to the surrounding material and has not undergone extensive deposition or erosion. Surrounding the crater are polygonal troughs in the smooth surface material. This polygon pattern is relatively common in the northern plains of Mars, and are primarily located in Acidalia Planitia, Elysium Planitia, and Utopia Planitia. These troughs are believed to be small grabbens, however, scientist are currently debating the origin of these features. The two most accepted hypotheses are that these grabbens either form as volcanic material cools and contracts, or are produced as sediment shrinks as a result of compaction. The Story When you think of Utopia, you probably don't think of a large Martian plain, riddled with troughs and pockmarked by craters. Of course, it may actually be a more fitting name than you think. When Sir Thomas More wrote his book about a fictitiously optimal place guided and governed by reason, he made up the word utopia from Greek words meaning 'nowhere.' Utopia Planitia became 'somewhere' for the first time, however, when its first visitor, the Viking 2 lander, settled down and analyzed the area. And scientists today are using their own reasoning and logic to discern even more about how this northern Martian plain developed geologically. Right now, scientists have two hypotheses for how the troughs seen here were formed. Because Utopia Planitia is a volcanic region of Mars, these rifts in the surface could have formed when volcanic material cooled and then contracted. Alternatively, this area might be made up of a lot of sediments - small particles of rock, soil, and dust deposited in the area. Just like

  1. The social oceanography of top oceanic predators and the decline of sharks: A call for a new field

    Science.gov (United States)

    Jacques, Peter J.

    2010-07-01

    The decline of top oceanic predators (TOPs), such as great sharks, and worldwide erosion of the marine food web is among the most important functional changes in marine systems. Yet, even though human pressures on sharks are one of the most important factors in the collapse of TOPs, the social science of shark fishing has not kept pace with the biophysical science. Such a gap highlights the need for a marine social science, and this paper uses the case of sharks to illustrate some advances that a coherent marine social science community could bring to science and sustainability, and calls for the development of this new field. Social oceanography is proposed as a “discursive space” that will allow multiple social science and humanities disciplines to holistically study and bring insight to a diverse but essential community. Such a community will not provide answers for the physical sciences, but it will add a new understanding of the contingencies that riddle social behavior that ultimately interact with marine systems. Such a field should reflect the broad and diverse approaches, epistemologies, philosophies of science and foci that are in the human disciplines themselves. Social oceanography would complete the triumvirate of biological and physical oceanography where human systems profoundly impact these other areas. This paper tests the theory that institutional rules are contingent on social priorities and paradigms. I used content analysis of all available (1995-2006) State of the World Fisheries and Aquaculture (SOFIA) reports from the United Nations Food and Agricultural Organization (FAO) to measure the symbolic behavior-i.e., what they say-as an indication of the value of sharks in world fisheries. Similar tests were also performed for marine journals and the Convention on Migratory Species of Wild Animals to corroborate these findings. Then, I present an institutional analysis of all international capacity building and regulatory institutions as they

  2. Two planets: Earth and Mars - One salt model: The Hydrothermal SCRIW-Model

    Science.gov (United States)

    Hovland, M. T.; Rueslaatten, H.; Johnsen, H. K.; Indreiten, T.

    2011-12-01

    One of the common characteristics of planets Earth and Mars is that both host water (H2O) and large accumulations of salt. Whereas Earth's surface-environment can be regarded as 'water-friendly' and 'salt hostile', the reverse can be said for the surface of Mars. This is because liquid water is stable on Earth, and the atmosphere transports humidity around the globe, whereas on planet Mars, liquid water is unstable, rendering the atmosphere dry and, therefore, 'salt-friendly'. The riddle as to how the salt accumulated in various locations on those two planets is one of long-lasting and great debate. The salt accumulations on Earth are traditionally termed 'evaporites', meaning that they formed by the evaporation of large masses of seawater. How the accumulations on Mars formed is much harder to explain, with a similar model, as surface water, representing a large ocean only existed briefly. Although water molecules and OH-groups may exist in abundance in bound form (crystal water, adsorbed water, etc.), the only place where free water is expected to be stable on Mars is within underground faults, fractures, and crevices. Here it likely occurs as brine or in the form of ice. Based on these conditions, a key to understanding the accumulation of large deposits of salt on both planets is linked to how brines behave in the subsurface when pressurized and heated beyond their supercritical point. At depths greater than about 3 km (i.e., a pressure, P>300 bars) water will no longer boil in a steam phase. Rather, it becomes supercritical and will form a supercritical water 'vapor' (SCRIW) with a specific gravity of typically 0.3 g/cm3. An important characteristic of SCRIW is its inability to dissolve the common sea salts. The salt dissolved in the brines will therefore precipitate as solid particles when brines (seawater on the Earth) move into the supercritical P&T-domain (above 400 C and 300 bars). Numerical modeling of a hydrothermal system in the Atlantis II Deep of the

  3. Geophysical Investigations in the Caucasus (1925 - 2012): Initial, Basic and Modern Stages

    Science.gov (United States)

    Eppelbaum, L. V.

    2012-04-01

    The Caucasian Mountains occupy an area of about 440,000 km2. A number of important mineral resources are concentrated there. Geophysical data on the geological structure of Caucasus can shed light on the basic principles of evolution of the Earth, the distribution of minerals and seismic activity. However, geophysical surveys under complex conditions are generally riddled by poor accessibility to certain mountainous regions, the unevenness of observation surfaces, as well as by a great variety and frequent changes of tectonic structures and geological bodies with variable physical properties. These factors either restrict geophysical surveys in difficult environments or confine the scope of useful information drawn from the results obtained. This has led to the development of special techniques in geophysical surveys, data processing and interpretation that draws heavily on the experience accumulated in the specific conditions of these mountainous regions. First applied geophysical observations in the Caucasus region - thermal measurements in boreholes - were carried out by Bazevich (1881) in the Absheron Peninsula. At the same time, start of the initial stage is usually referred to as the mid 20-s of the XX century, when the rare, but systematic geophysical observations (mainly gravity and magnetic) were begun in some Caucasian areas. Somewhat later began to apply the resistivity method. Mid 30-s is characterized by the beginning of application of borehole geophysics and seismic prospecting. The marine seismics firstly in the former Soviet Union was tested in the Caspian Sea. In general, the initial stage is characterized by slow, but steady rise (except during World War II) lasted until 1960. A basic stage (1960-1991) is characterized by very intensive employment of geophysical methods (apparently, any possible geophysical methods were tested in this region). At this time the Caucasus region is considered in the former Soviet Union as a geophysical polygon for

  4. Mathematical fundamentals for the noise immunity of the genetic code.

    Science.gov (United States)

    Fimmel, Elena; Strüngmann, Lutz

    2018-02-01

    Symmetry is one of the essential and most visible patterns that can be seen in nature. Starting from the left-right symmetry of the human body, all types of symmetry can be found in crystals, plants, animals and nature as a whole. Similarly, principals of symmetry are also some of the fundamental and most useful tools in modern mathematical natural science that play a major role in theory and applications. As a consequence, it is not surprising that the desire to understand the origin of life, based on the genetic code, forces us to involve symmetry as a mathematical concept. The genetic code can be seen as a key to biological self-organisation. All living organisms have the same molecular bases - an alphabet consisting of four letters (nitrogenous bases): adenine, cytosine, guanine, and thymine. Linearly ordered sequences of these bases contain the genetic information for synthesis of proteins in all forms of life. Thus, one of the most fascinating riddles of nature is to explain why the genetic code is as it is. Genetic coding possesses noise immunity which is the fundamental feature that allows to pass on the genetic information from parents to their descendants. Hence, since the time of the discovery of the genetic code, scientists have tried to explain the noise immunity of the genetic information. In this chapter we will discuss recent results in mathematical modelling of the genetic code with respect to noise immunity, in particular error-detection and error-correction. We will focus on two central properties: Degeneracy and frameshift correction. Different amino acids are encoded by different quantities of codons and a connection between this degeneracy and the noise immunity of genetic information is a long standing hypothesis. Biological implications of the degeneracy have been intensively studied and whether the natural code is a frozen accident or a highly optimised product of evolution is still controversially discussed. Symmetries in the structure of

  5. Diagenetic evolution and stable isotopes of Lower Permian platform marginal carbonates (Trogkofel Limestone, Carnic Alps, Austria)

    Science.gov (United States)

    Schaffhauser, Maria; Krainer, Karl; Sanders, Diethard Gerald; Spötl, Christoph

    2010-05-01

    The Trogkofel massif in the Carnic Alps, Austria/Italy, consists of a succession up to 400 m thick of limestones deposited along a platform margin (Trogkofel Limestone; Artinskian). The top of the Trogkofel Limestone is erosively overlain by the Tarvis Breccia. Up-section, the Trogkofel Limestone consists of well-bedded shallow-water bioclastic limestones with intercalated mud mounds, overlain by thick-bedded to unbedded limestones (bioclastic grainstones, packstones, rudstones) and cementstone mounds rich in phylloid algae, Tubiphytes, bryozoans and Archaeolithoporella. In the cementstone mounds, bioclasts are coated by thick fringes and botryoids of fibrous calcite, and of calcite spar that probably represents calcitized aragonite. Primary and intrinsic pores are filled by microbialite, and/or by mudstone to bioclastic wackestone. Shallow-water bioclastic grainstones are cemented by isopachous fringes of fibrous calcite, or by sparry calcite. Throughout the succession, evidence for meteoric-vadose dissolution is present. The Trogkofel Limestone is riddled by palaeokarstic dykes and caverns filled by (a) isopachous cement fringes up to a few decimetres thick, and/or (b) by red, geopetally-laminated lime mudstone to bio-lithoclastic wackestone; geopetal laminasets locally display convolute bedding. Small dissolution cavities are filled by grey internal sediment, or by crystal silt. Brecciated internal sediments overlain by unbrecciated, geopetally-laminated infillings record deformation during or after deposition of the Trogkofel Limestone. Polyphase fractures cemented by calcite may cross-cut both internal sediments and host rock. In the Trogkofel Limestone, local dolomitization is common. Replacement dolomites show a wide range of shapes and fabrics, including: (a) fine-crystalline anhedral xenotopic fabric, (b) coarse-crystalline subhedral to euhedral, hypidiotopic to idiotopic fabric of turbid or optically zoned crystals, and (c) saddle dolomite as replacement

  6. A universal salt model based on under-ground precipitation of solid salts due to supercritical water `out-salting'

    Science.gov (United States)

    Rueslåtten, H.; Hovland, M. T.

    2010-12-01

    One of the common characteristics of planets Earth and Mars is that both host water (H2O) and large accumulations of salt. Whereas Earth’s surface-environment can be regarded as ‘water-friendly’ and ‘salt hostile’, the reverse can be said for the surface of Mars. This is because liquid water is stable on Earth, and the atmosphere transports humidity around the globe, whereas on planet Mars, liquid water is unstable, rendering the atmosphere dry and, therefore, ‘salt-friendly’. The riddle as to how the salt accumulated in various locations on those two planets, is one of long-lasting and great debate. The salt accumulations on Earth are traditionally termed ‘evaporites’, meaning that they formed as a consequence of the evaporation of large masses of seawater. How the accumulations on Mars formed is much harder to explain, as an ocean only existed briefly. Although water molecules and OH-groups may exist in abundance in bound form (crystal water, adsorbed water, etc.), the only place where free water is expected to be stable on Mars is within underground faults, fractures, and crevices. Here it likely occurs as brine or in the form of ice. Based on these conditions, a key to understanding the accumulation of large deposits of salt on both planets is linked to how brines behave in the subsurface when pressurized and heated beyond their supercritical point. At depths greater than about 3 km (P>300 bars) water will no longer boil in a steam phase. Rather, it becomes supercritical and will attain the phase of supercritical water vapor (SCRIW) with a specific gravity of typically 0.3 g/cm3. An important characteristic of SCRIW is its inability to dissolve the common sea salts. The salt dissolved in the brines will therefore precipitate as solid particles when brines (seawater on the Earth) move into the supercritical P&T-domain (T>400°C, P>300 bars). Numerical modeling of a hydrothermal system in the Atlantis II Deep of the Red Sea indicates that a

  7. Paradoxical Roles of Nanoparticles in Cancer Therapeutics and Carcinogenesis

    Science.gov (United States)

    Despeaux, Emily

    Nanoparticles (NPs) are becoming increasingly common in consumer goods and are under investigation for a variety of industrial and biomedical applications. However, challenges in determining NP toxicity may prevent them from reaching their full potential. NPs cannot be treated as single class for toxicity evaluations. Even among particles made from the same material, particle-specific physical properties, including size, shape, surface charge, agglomeration state, and surface modifications have a strong effect on the toxicity. Even so, the obstacles to conclusively and reproducibly evaluating toxicity span all NP classes. NP literature is riddled with confusing and often contradictory reports regarding the biocompatibility of both engineered NPs, designed with biocompatibility as a priority, and NPs from occupational or environmental exposures. Incomplete NP characterization and sample inhomogeneity represent major confounding factors in disparate results from seemingly comparable study setups. Additionally, NPs can interfere with many conventional toxicity screening methods. Inappropriate doses, exposure routes, and toxicity endpoints further diminish the utility of many published studies. Given the burgeoning interest in NP-based therapeutic agents, consistent, reliable standards are needed to ensure the biocompatibility of new formulations. To those ends, the synthesis, characterization, and in vitro toxicity of a multi-functional NP therapeutic were investigated (Chapter 2). Specifically, superparamagnetic iron oxide nanoparticles (SPIONs) were coated with amphiphilic polymer and functionalized with antisense oligonucleotides targeting survivin, an anti-apoptotic protein that is highly overexpressed in cancer. SPION physical properties, including particle size and composition, were characterized at each step of synthesis. Our results showed that the SPION platform is biocompatible and capable of delivering functional antisense oligonucleotides to regulate

  8. Les proverbes dans Kongo Proverbs and the Origins of Bantu Wisdom par Mukumbuta Lisimba

    Directory of Open Access Journals (Sweden)

    Ludwine Mabika Mbokou

    2011-10-01

    Full Text Available

    Résumé: On emploie tous les jours des proverbes, des maximes, des devinettes et des dictons.Malgré les progrès techniques des denières décénies en matière d'outils didactiques, le proverbefait partie du quotidien des sociétés africaines en particulier et de celles du monde en général. Ilreste un instrument d'éducation indispensable et vital pour les générations futures, et quiconquedésire un conseil ou une orientation dans une certaine situation s'y réfère. Il fait partie intégrantede l'acte de communication.À la lumière des analyses du Dr Lisimba de certains proverbes de la famille bantu, nousdécouvrons l'importance que revêt la dynamique du langage offert par les proverbes. Ils peuventainsi être employés comme données dans la compilation de dictionnaires. En effet, pour la disciplinedes sciences du langage qu'est la lexicographie, le traitement des proverbes et idiomes estd'une importance capitale parce que ces derniers sont le véhicule de la culture et des moeurs d'unpeuple. Ainsi, pour mener à bien une telle entreprise, le lexicographe devra choisir le traitement àl'intérieur de la liste centrale, sinon à l'extérieur de la liste centrale, l'option la plus profitable pourlui restant une classification thématique qui tient compte non seulement de l'aspect sémantique duproverbe, mais aussi de son aspect formel.

    Mots-clés: ANALYSE FORMELLE, ANALYSE SÉMANTIQUE, CLASSIFICATION THÉMATIQUE,DIDACTIQUE, DICTIONNAIRE, GENRE PROVERBIAL, IDIOMES, LEXICOGRAPHE,LEXICOGRAPHIE, LISTE CENTRALE, LITTÉRATURE ORALE, PRÉ-TEXTES, POST-TEXTES,PROVERBES

    Abstract: Proverbs according to Kongo Proverbs and the Origins of Bantu Wisdom by Mukumbuta Lisimba. Proverbs, maxims, riddles and sayings are used every day. In spite of the technical progress during the last decades as far as didactic tools are concerned, the proverb forms part of the daily life of African societies in particular and those of the world in

  9. Grainstones and cementstone mounds: The Trogkofel summit section (Lower Permian, Carnic Alps, Austria).

    Science.gov (United States)

    Schaffhauser, M.; Sanders, D.; Krainer, K.

    2009-04-01

    are overgrown by abundant, thick fringes and botryoids of fibrous cement that is interpreted as calcitized aragonite cement. In addition, brachiopods, crustose red algae, and a few solitary and colonial rugose corals are typical. By volume, the former aragonite cement comprises the majority of the mounds. Intrinsic pores within the cementstone fabrics typically are filled by micropeloidal grainstone and/or by lime mudstone. The Trogkofel Limestone is locally dolomitized. Replacement dolomites show a wide range of crystal shapes and textures, but overall comprise (a) finely-crystalline, limpid dolostone of xenotopic or hypidiotopic fabrics that broadly mimick the texture of replaced sediment and cements, (b) coarse-crystalline fabrics of hypidiotopic to idiotopic, limpid or optically zoned dolomite, and (c) replacement saddle dolomite. The Trogkofel Limestone is riddled by karstic dykes and caverns that are mainly filled by, both or either of, geopetally-laminated red lime mudstone, terrigenous red sandstones, or thick fringes of fibrous cement. In the karstic cavity fills, packages of convolute geopetal lamination and brecciated internal sediments (internal seismites) overlain by infills with non-convolute lamination, fracture of fibrous cements, and dykes filled by multi-phase fracture breccias record tectonism during or after deposition of the Trogkofel Limestone. The Trogkofel Limestone is capped by a truncation surface which, in turn, is overlain by an interval of extremely poorly sorted, thick-bedded breccias with a former matrix of lime mudstone ("Trogkofel Breccia"). Both the components and the matrix of the Trogkofel Breccia are dolomitized. We interpret the facies and facies architecture of the eastern cliff section of Trogkofel as succession from the seaward side of a "grainstone-dominated" platform margin with cementstone mounds. The lack of clear-cut vertical trends in prevalent facies suggests that the platform margin developed mainly by aggradation. The

  10. Mapping Near-Earth Hazards

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    How can we hunt down all the near-Earth asteroids that are capable of posing a threat to us? A new study looks at whether the upcoming Large Synoptic Survey Telescope (LSST) is up to the job.Charting Nearby ThreatsLSST is an 8.4-m wide-survey telescope currently being built in Chile. When it goes online in 2022, it will spend the next ten years surveying our sky, mapping tens of billions of stars and galaxies, searching for signatures of dark energy and dark matter, and hunting for transient optical events like novae and supernovae. But in its scanning, LSST will also be looking for asteroids that approach near Earth.Cumulative number of near-Earth asteroids discovered over time, as of June 16, 2016. [NASA/JPL/Chamberlin]Near-Earth objects (NEOs) have the potential to be hazardous if they cross Earths path and are large enough to do significant damage when they impact Earth. Earths history is riddled with dangerous asteroid encounters, including the recent Chelyabinsk airburst in 2013, the encounter that caused the kilometer-sized Meteor Crater in Arizona, and the impact thought to contribute to the extinction of the dinosaurs.Recognizing the potential danger that NEOs can pose to Earth, Congress has tasked NASA with tracking down 90% of NEOs larger than 140 meters in diameter. With our current survey capabilities, we believe weve discovered roughly 25% of these NEOs thus far. Now a new study led by Tommy Grav (Planetary Science Institute) examines whether LSST will be able to complete this task.Absolute magnitude, H, of asynthetic NEO population. Though these NEOs are all larger than 140 m, they have a large spread in albedos. [Grav et al. 2016]Can LSST Help?Based on previous observations of NEOs and resulting predictions for NEO properties and orbits, Grav and collaborators simulate a synthetic population of NEOs all above 140 m in size. With these improved population models, they demonstrate that the common tactic of using an asteroids absolute magnitude as a

  11. The Lord of Rings - the mysterious case of the stolen rings: a critical analysis of an informal education activity

    Science.gov (United States)

    Sandrelli, S.

    2011-10-01

    "The Lord of Rings - the mysterious case of the stolen rings" is a live astronomical role-playing game for kids aged 10 -13 [1]. Its goal is to introduce them to some of the main topics of the Solar System: a) the role of gravity; b) the distribution of mass & light; c) the effects of rotation; d) the distribution of water. The game was held at several Science Festival in Italy (Perugia, Genova, Fiorano, Bologna) obtaining great success. Teams of about 6-8 members are introduced to Mr Schioppanelli, the astro-detective of the town (the name is a pun: it reminds Schiaparelli, the famous italian astronomer, and it is a slang expression meaning "ring-breaker"). Mr Schioppanelli has his office in an "gastronomical astronomical observatory", known as The Red Giant Pizzeria. Schioppanelli informs the kids that a mysterious Centaur succeded in stealing the rings of Saturn. The partecipants are appointed astro-detectives incharge and asked to find the rings by browsing around the Solar System, which is scaled so as to fit the town historical centre or a pedestrian area, going from the Sun to Saturn or beyond, depending on the actual area at disposal. Great care must be taken allowing children playing only in a car-free area of the town. At the right scaled distances, the partecipants meet characters playing as the various planets. The kids can talk to them after solving a riddle, obtaining useful informations. A special characters play as a comet, timely going in and out of the inner solar system. The teams can also talk to some shepherdmoons of the rings. They easily discover that the rings were totally destroyed by the Centaur: a real disaster! They are also suggested to gather the necessary ingredients (gravity, light, rotation, inclination, dust and water, represented by simple objects like apples, spinning tops and so on) to rebuild the rings. The kids can buy the ingredients from different planets: every planet has ingredients in quantities which are proportionate to

  12. Influence of religion on socio-economic situation of the world in present circumstances Влияние религии на социально-экономическое положение стран мира в современных условиях

    Directory of Open Access Journals (Sweden)

    Ivashchenko Marina V.

    2012-10-01

    Full Text Available In this paper the non-economic factors such as religion, is part of the cultural heritage, which is riddled with moral-ethical principles, intertwined with religious dogma. We prove that the moral climate in society due to a set of rules and regulations prevailing in it, and give advice on behavior in various situations, including with respect to economic behavior, acting out of the subconscious. On the basis of GDP per capita in the conclusions regarding the nature of the influence of religion on the different areas of the state of the national economy.В статье исследован такой неэкономический фактор, как религия, которая является частью культурного наследия, пронизанного морально-этическими принципами, переплетенными с религиозными догмами. Доказано, что морально-нравственный климат в обществе обусловлен набором норм и правил, царящих в нем и дающих рекомендации относительно поведения в различных жизненных ситуациях, в том числе и относительно экономического поведения, действуя из подсознания. На основе анализа показателя ВВП на душу населения сделаны выводы о характере влияния различных направлений религии на состояние национальной экономики.

  13. National volcanic ash operations plan for aviation

    Science.gov (United States)

    ,; ,

    2007-01-01

    International Civil Aviation Organization’s (ICAO) International Airways Volcano Watch. This plan defines agency responsibilities, provides a comprehensive description of an interagency standard for volcanic ash products and their formats, describes the agency backup procedures for operational products, and outlines the actions to be taken by each agency following an occurrence of a volcanic eruption that subsequently affects and impacts aviation services. Since our most recent International Conference on Volcanic Ash and Aviation Safety, volcanic ash-related product and service activities have grown considerably along with partnerships and alliances throughout the aviation community. In January 2005, the National Oceanic and Atmospheric Administration’s National Centers for Environment Prediction began running the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model in place of the Volcanic Ash Forecast Transport and Dispersion (VAFTAD) model, upgrading support to the volcanic ash advisory community. Today, improvements to the HYSPLIT model are ongoing based on recommendations by the OFCM-sponsored Joint Action Group for the Selection and Evaluation of Atmospheric Transport and Diffusion Models and the Joint Action Group for Atmospheric Transport and Diffusion Modeling (Research and Development Plan). Two international workshops on volcanic ash have already taken place, noticeable improvements and innovations in education, training, and outreach have been made, and federal and public education and training programs on volcanic ash-related products, services, and procedures iv continue to evolve. For example, in partnership with Embry-Riddle Aeronautical University and other academic institutions, volcanic ash hazard and mitigation training has been incorporated into aviation meteorology courses. As an essential next step, our volcanic ash-related efforts in the near term will be centered on the development of an interagency implementation plan to

  14. Survey the frequency and type of Fungal Contaminants in Animal Feed of Yazd Dairy Cattles

    Directory of Open Access Journals (Sweden)

    mohammad taghi ghaneian

    2016-04-01

    by using thermometer and portable hygrometer at the time of sampling. Samples were transferred to medical mycology laboratory in paramedical school by sterile containers. Samples were cultured on Sab ouraud dextrose agar plates based on standard method. Isolated fungal colonies were firstly enumerated and identified using macroscopic and microscopic characteristics for determination of their genus and species of saprophytic and toxic fungi. The suspected fungi with definitive diagnosis by the use of the men tioned methods were then identified by performing slide culture by Riddle method. For the detection of aflatoxin producer species UV radiation was used. Results were analyzed statistically by Chi-square and Mann-Whitney test using SPSS 16 software. Results and Discussion Saprophytic hyphomycets including Cladosporium, Alternation Penicilium, Verticillium, Aspergillus, Penicillium species and yeast were the most prevalent isolated fungi from cattle feeds in current study. Bread waste showed maximum contamination with opportunistic fungi such as Mucor and Rhizopus species, other saprophyte moulds and yeasts. Wheat straw had the highest contamination of aflatoxin-producing toxic fungi particularly Aspergillus flavus. Silage and concentrate were ranked as highest average contamination with 42600 and 40600 CFU/g, respectively in present study. There was seen a significant relationship between the average humidity of the environment of open and covered storage of feed with frequency of isolated fungal species (P< 0.001. In indoor environments, the humidity was higher than outdoors, and this is one of the factors effecting the increase aggregation in animal feeds stored in indoor storages. Results of present study were supported by similar previous studies that can be beneficial for the man agement of cattle feeds and public health surveillance particularly in disorders of aflatoxin. Conclusion According to results of present study, there are a high fungal contamination

  15. Fingerprinting the Milky Way

    Science.gov (United States)

    2007-03-01

    Using ESO's Very Large Telescope, an international team of astronomers has shown how to use the chemical composition of stars in clusters to shed light on the formation of our Milky Way. This discovery is a fundamental test for the development of a new chemical tagging technique uncovering the birth and growth of our Galactic cradle. The formation and evolution of galaxies, and in particular of the Milky Way - the 'island universe' in which we live, is one of the major puzzles of astrophysics: indeed, a detailed physical scenario is still missing and its understanding requires the joint effort of observations, theories and complex numerical simulations. ESO astronomer Gayandhi De Silva and her colleagues used the Ultraviolet and Visual Echelle Spectrograph (UVES) on ESO's VLT to find new ways to address this fundamental riddle. ESO PR Photo 15/07 ESO PR Photo 15/07 The Cluster Collinder 261 "We have analysed in great detail the chemical composition of stars in three star-clusters and shown that each cluster presents a high level of homogeneity and a very distinctive chemical signature," says De Silva, who started this research while working at the Mount Stromlo Observatory, Australia. "This paves the way to chemically tagging stars in our Galaxy to common formation sites and thus unravelling the history of the Milky Way," she adds. "Galactic star clusters are witnesses of the formation history of the Galactic disc," says Kenneth Freeman, also from Mount Stromlo and another member of the team. "The analysis of their composition is like studying ancient fossils. We are chasing pieces of galactic DNA!" Open star clusters are among the most important tools for the study of stellar and galactic evolution. They are composed of a few tens up to a few thousands of stars that are gravitationally bound, and they span a wide range of ages. The youngest date from a few million years ago, while the oldest (and more rare) can have ages up to ten billion years. The well

  16. Obituary: Edward R. (Ted) Harrison, 1919-2007

    Science.gov (United States)

    Irvine, William M.; Arny, Thomas T.; Trimble, Virginia

    2007-12-01

    Japanese. He was fascinated with Olbers' Paradox (which he pointed out had not been discovered by Olbers and was not really a paradox, but a riddle), the question of why the sky is dark at night if the universe is filled with bright stars and galaxies. His book, Darkness at Night, points out that this is not primarily because the universe is expanding, nor because light is absorbed, but rather because the stars and galaxies have had only about 15 billion years to radiate and indeed do not have enough energy to keep radiating for much longer. He points out that this conclusion was anticipated in the writings of Edgar Allan Poe! Ted's monograph, Cosmology: The Science of the Universe, has gone through some seven printings and two editions. Again typical of his command of the history of science, he describes the problem of the "cosmic edge" of the universe by quoting fifth-century BCE soldier-philosopher Archytas of Tarentum, who asked what happens to a spear that is hurled across the outer boundary of the universe? But to many of us, Ted's most intriguing book is Masks of the Universe (second edition published just three years ago). Is our present cosmology, with ordinary matter, dark matter, and dark energy, but another mask obscuring a Universe which will remain perforce forever unknown? Will the ?CDM model be looked upon some day in the same way that we now view the medieval, the geometric, or the mythic universes of earlier eras? Read the book and form your own opinion!

  17. Hipparcos reveals that the Milky Way is changing shape

    Science.gov (United States)

    1998-04-01

    deformations of its disk. About half of all other disk galaxies are seen to be misshapen. This remarkably high proportion may mean that galaxies are so rigid that any warp, once established, lasts for billions of years. Alternatively, galaxies may be very floppy, with new warps being created all the time. The Hipparcos result on the Milky Way may favour the latter, more dynamic interpretation. The riddle of what warps galaxies has puzzled astronomers for decades. Explanations on offer range from intergalactic winds to magnetic contortions. A popular theory blames the warp in the Milky Way on the gravitational pull of invisible dark matter in the halo of the Galaxy. This would imply that the present warp should be a long-lived phenomenon. As the warp may now be only temporary, other explanations will be favoured. Mario Lattanzi, of the Turin group, puts it this way: "As is often the case in experimental science, better experimental data challenge our current understanding of how the Milky Way works." Prominent among the rival proposals about the warping of galaxies is the gravitational (tidal) effect of other galaxies passing close by. In the case of the Milky Way, the Magellanic Clouds and the recently discovered Sagittarius Dwarf Galaxy are candidates as warping agents. But Smart and his colleagues confess themselves to be baffled. "We are obliged to conclude," they write, "that there is currently no convincing interpretation of the implications of Hipparcos data for the dynamics of the warp in the Galactic disk." The reference to the "Nature" paper is: Vol. 392, pp. 471-473. The authors are R.L. Smart,R. Drimmel, M.G. Lattanzi (Osservatorio Astronomico di Torino, Pino Torinese, TO 10025, Italy) and J.J. Binney (Department of Physics, University of Oxford, Oxford OX1 3NP, UK).

  18. Obituary: Hakki Ogelman (1940-2011)

    Science.gov (United States)

    Orio, Marina

    2011-12-01

    sabbatical year back at Goddard, Hakki took leave from Ankara to help the development of a university in the rural area of Adana and became the Dean of Basic Sciences at Çukurova University. He established a group working on exploitation techniques of solar energy and planned for himself and his wife a solar house that was built on campus. Hakki was a member of the Turkish Academy of Sciences, served as a member of the Executive Science Board for the Scientific and Technical Research Council of Turkey from 1976-1984, and represented Turkey on international science councils and co-operations. Turkey during those years was in turmoil, first apparently on the brink of a civil war and later governed by a strict military regime. Upsetting personal experiences convinced Hakki that Turkey had become too difficult for a free intellectual person, so he took a prolonged sabbatical at the Max Planck Institute for Extraterrestrial Physics in Garching near Munich, where he had already spent several summers and kept in touch with an international and vibrant community of scientists working on high-energy astrophysics. What started as a sabbatical stretched into almost 8 years. From gamma rays he moved to lower energies, X-rays, and made several interesting discoveries first with EXOSAT, then with ROSAT, the second imaging telescope in X-rays. Hakki was broadly educated across many areas of physics, astronomy and science in general. He was very curious and an avid reader of science and non-science books and articles. Such broad horizons helped him think "outside the box." He was the first to observe novae as accreting and exploding white dwarfs in binary systems in X-rays, thereby observing the "naked white dwarf" to obtain clues on its mass, chemical composition and possible evolutionary path toward a supernova Ia explosion. Hakki's work on cooling neutron stars, pulsars and their nebulae (his main interest) was always innovative. One difficult riddle he hoped to solve was the

  19. Black Hole in Search of a Home

    Science.gov (United States)

    2005-09-01

    is no trace of stellar light, down to very faint levels, in the surrounding of the quasar. A strongly perturbed galaxy, showing all signs of a recent collision, is also seen on the HST images 2 arcseconds away (corresponding to about 50,000 light-years), with the VLT spectra showing it to be presently in a state where it forms stars at a frantic rate. "The absence of a massive host galaxy, combined with the existence of the blob and the star-forming galaxy, lead us to believe that we have uncovered a really exotic quasar, says team member Frédéric Courbin (Ecole Polytechnique Fédérale de Lausanne, Switzerland). "There is little doubt that a burst in the formation of stars in the companion galaxy and the quasar itself have been ignited by a collision that must haven taken place about 100 million years ago. What happened to the putative quasar host remains unknown." HE0450-2958 constitutes a challenging case of interpretation. The astronomers propose several possible explanations, that will need to be further investigated and confronted. Has the host galaxy been completely disrupted as a result of the collision? It is hard to imagine how that could happen. Has an isolated black hole captured gas while crossing the disc of a spiral galaxy? This would require very special conditions and would probably not have caused such a tremendous perturbation as is observed in the neighbouring galaxy. Another intriguing hypothesis is that the galaxy harbouring the black hole was almost exclusively made of dark matter. "Whatever the solution of this riddle, the strong observable fact is that the quasar host galaxy, if any, is much too faint", says team member Knud Jahnke (Astrophysikalisches Institut Potsdam, Germany). The report on HE0450-2958 is published in the September 15, 2005 issue of the journal Nature ("Discovery of a bright quasar without a massive host galaxy" by Pierre Magain et al.).

  20. Astronomers celebrate a year of new Hubble results

    Science.gov (United States)

    1995-02-01

    Space Telescope to make accurate measurements of the distance of Ml 00, a far away galaxy located in the Virgo cluster of galaxies. To do this they used a number of Cepheid variable stars, rare objects that change in brightness over a regular period. Because astronomers know that there is a direct link between the period of the Cepheid's pulsation and its actual brightness, they can do a simple calculation to work out the distance to the object by comparing its actual brightness with how bright it appears to Hubble. The astronomers had to study more than 40,000 stars before finding the 20 Cepheids they used for their calculations. The results revealed that M100 lies 56 million light years from Earth. With this, astronomers calculated that the Universe is expanding at a rate of 80 kilometres per second per megaparsec (a megaparsec is 3,261,600 light years). This is much faster than astronomers had expected. On the basis of this value for the Hubble Constant, the Universe must be aged somewhere between eight and twelve billion years old. But, this flies in the face of established facts. We know there are stars in our Universe that are 16 billion years old - how can they be older than the Universe in which they exist? It could be that the theory that explains the evolution of stars or the Big Bang theory are wrong. Or perhaps it is the observations that are incorrect. Hubble astronomers soon hope to solve this riddle by taking further measurements to refine their figures. "This is a programme that we know is going to give us some really firm answers in the next three to five years," said Dr Macchetto, one of the 15 European astronomers at the Space Telescope Science Institute. "It will take that time to collect and analyse enough data." Part of the Universe is missing ! Once astronomers know the expansion rate of the Universe they will be one step away from determining its fate. But it will be a big step - for astronomers will have to work out the mass of the Universe and