Peter in the Gospel of Mark and in Early Christianity in Rome

DEFF Research Database (Denmark)

Willert, Niels

1997-01-01

Artiklen gennemgår Markusevangeliets portræt af apostlen Peter og drøfter spørgsmålet, hvorfor Peter er så negativt skildret hos Markus. Litterære og pædagogiske (indirekte formaning til datidens kristne) intentioner forklarer først og fremmest dette træk hos Markus. Men også historiske spørgsmål...

Fiction and Religion: How Narratives About the Supernatural Inspire Religious Belief

OpenAIRE

Davidsen, M.A.

2016-01-01

Thematic issue on 'Fiction and Religion: How Narratives About the Supernatural Inspire Religious Belief', volume 46(4) of Religion. The thematic issue inclues the following articles: Davidsen, Markus Altena, "Fiction and Religion: How Narratives About the Supernatural Inspire Religious Belief – Introducing the Thematic Issue". Petersen, Anders Klostergaard, "The Difference Between Religious Narratives and Fictional Literature: A Matter of Degree Only". Davidsen, Markus Altena, "The Religious ...

The red atom - the help to Russia of German scientists between 1945 - 1961

International Nuclear Information System (INIS)

Andurand, R.

2009-01-01

The fifth chapter of the cooperation between German scientists and USSR from 1945 to 1961 is tackled in this issue. It treats how the german scientists were ostracized and then, their return to Germany. The returns began in 1954. The lives of Gustav Hertz, Heinz Barwich, Bruno Pontecorvo, klaus Fuchs, Manfred von Ardenne, Peter Adolf von Thiessen, Max Christian Theodor Steenbeck, Gernot Zippe, Max Vollmer, are in relation with the development of nuclear research where they brought their contribution. (N.C.)

Metformin Therapy for Fanconis Anemia

Science.gov (United States)

2017-08-01

AWARD NUMBER: W81XWH-16-1-0300 TITLE: Metformin Therapy for Fanconis Anemia PRINCIPAL INVESTIGATOR: Markus Grompe CONTRACTING ORGANIZATION... Anemia 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1-0300 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Markus Grompe 5d. PROJECT NUMBER 5e. TASK...298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 This award pertains to the treatment of the inherited bone marrow failure syndrome Fanconi’s Anemia

Bookshelf (Quantum Fields on a Lattice, by Istvan Montvay and Gernot Muenster)

Energy Technology Data Exchange (ETDEWEB)

Wolff, U.

1994-09-15

In four space-time dimensions, lattice regularization often represents the only non-perturbative definition of a quantum field theory. On this basis, and in connection with numerical simulation techniques and the spreading of powerful parallel computers, more and more realistic calculations are carried out. There has been a great need for a textbook for advanced students to enter this field. While the recent book by H. J. Rothe (Lattice Gauge Theories, Word Scientific) covers the more formal and analytic aspects, this new book provides excellent coverage of a large section of the field, including details of Monte Carlo simulations and algorithms. It is well suitable to prepare a student for reading reviews as they appear in annual proceedings of lattice conferences. The book starts with an introduction to euclidean fields and path-integrals including nontrivial details like reflection positivity. Here the authors succeed very well in avoiding the use of both over-formal machinery as well as an unduly schematic and superficial presentation. Then several sections introduce lattice scalar, fermion, and gauge fields in the traditional division of field theory texts. Lattice specialties, like the semi-analytic Luescher-Weisz solution and the problem of fermion doubling, are enlarged on. Bridges toward current research are included in chapters on QCD and Higgs and Yukawa models. The book ends with practical considerations about algorithms, including hybrid Monte Carlo, and error analysis. This textbook is an excellent introduction to present day lattice methods for particle physics. In its scope it is almost unrivalled and is a must for every student taking up the subject. The researcher in the field will value it as a standard reference and entry point to the literature.

Bookshelf (Quantum Fields on a Lattice, by Istvan Montvay and Gernot Muenster)

International Nuclear Information System (INIS)

Wolff, U.

1994-01-01

In four space-time dimensions, lattice regularization often represents the only non-perturbative definition of a quantum field theory. On this basis, and in connection with numerical simulation techniques and the spreading of powerful parallel computers, more and more realistic calculations are carried out. There has been a great need for a textbook for advanced students to enter this field. While the recent book by H. J. Rothe (Lattice Gauge Theories, Word Scientific) covers the more formal and analytic aspects, this new book provides excellent coverage of a large section of the field, including details of Monte Carlo simulations and algorithms. It is well suitable to prepare a student for reading reviews as they appear in annual proceedings of lattice conferences. The book starts with an introduction to euclidean fields and path-integrals including nontrivial details like reflection positivity. Here the authors succeed very well in avoiding the use of both over-formal machinery as well as an unduly schematic and superficial presentation. Then several sections introduce lattice scalar, fermion, and gauge fields in the traditional division of field theory texts. Lattice specialties, like the semi-analytic Luescher-Weisz solution and the problem of fermion doubling, are enlarged on. Bridges toward current research are included in chapters on QCD and Higgs and Yukawa models. The book ends with practical considerations about algorithms, including hybrid Monte Carlo, and error analysis. This textbook is an excellent introduction to present day lattice methods for particle physics. In its scope it is almost unrivalled and is a must for every student taking up the subject. The researcher in the field will value it as a standard reference and entry point to the literature.

Practical electron dosimetry: a comparison of different types of ionization chambers

International Nuclear Information System (INIS)

Dohm, O.S.; Christ, G.

2002-01-01

Since Markus chambers are no longer recommended in the 1997 DIN 6800-2 version there are uncertainties as to the use of alternative chamber types for electron dosimetry. Therefore, we performed a comparison between different types of ionization chambers. In particular, the widespread Farmer and Roos chambers were compared with the Markus chamber for polarity effect, chamber-to-chamber variation, and deviations of the measured absorbed dose relative to the value obtained with the Roos chamber (which is regarded as an ideal Bragg-Gray-chamber). The perturbation correction factor at 60 Co radiation was determined experimentally as 1,029 ± 0,5% (Roos chamber) and 1,018 ± 0,5% (Markus chamber) for the investigated plane-parallel chambers. In addition, we could show that the Roos chambers do not have a larger chamber-to-chamber variation than the Farmer chambers. Likewise, our results suggest that Farmer chambers could be used for electron energies above 6 MeV. (orig.) [de

Tendencias recientes en los estudios de usuarios: investigación acción y métodos cualitativos Recent trends in user studies: action research and qualitative methods

Directory of Open Access Journals (Sweden)

T. D. Wilson

2003-06-01

Full Text Available Este artículo fue encargado por el profesor Gernot Wersig de la Freie Universität de Berlín en 1980, como parte de su proyecto, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation. Intenta explicar lo que era, en esa época, una perspectiva nueva sobre metodologías apropiadas para el estudio de la conducta humana de búsqueda de la información, centrándose en los métodos cualitativos y la investigación acción, argumentando que la aplicación de la investigación en información depende de su adopción en los procesos administrativos de las organizaciones, antes que en su relación auto-evidente con cualquier cuerpo de teoría. Se presenta ahora tal como fuera originalmente escrito, con las figuras re-elaboradas.This paper was commissioned by Professor Gernot Wersig of the Freie Universität, Berlin in 1980, as part of his Project, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation. It attempted to set out what was, for the time, a novel perspective on appropriate methodologies for the study of human information seeking behaviour, focusing on qualitative methods and action research, arguing that the application of information research depended upon its adoption into the managerial processes of organizations, rather than its self-evident relationship to any body of theory. It is presented here as it was originally written, with the figures re-drawn.

Fisiognomica emozionale. Affordances, estasi, atmosfere

Directory of Open Access Journals (Sweden)

Tonino Griffero

2015-06-01

Full Text Available Through an atmospherological approach, primarily inspired by the so-called Aisthetik or New Aesthetics (Gernot Böhme and the New Phenomenology (Hermann Schmitz, the paper defines the atmospheric perception as a first pathemic impression and investigates the relationship between this kind of perception and the expressive qualities of the surrounding spaces. The aim is to understand atmospheres as (amodal, transmodal, sinaesthetic affordances that permeate the lived space, namely as ‘ecological’ and affective invites or meanings which are ontologically rooted in things and quasi-things.

Atmosphere beyond Poetics

DEFF Research Database (Denmark)

Wieczorek, Izabela

2014-01-01

Defined by German philosopher Gernot Böhme as a ‘fundamental concept of a new aesthetics’ (Böhme 2003), the notion of atmosphere has been widely discussed across many disciplinary fields over the last few decades. It has taken a central stage also in architectural debate, leading to both conceptual......, the notion of atmosphere is presented as parallactic for designing experience in architectural fields, since it transgresses formal and material boundaries of bodies, opening a new gap that exposes the orthodox space-body-environment relationships to questions. It leads to the dissolution...

Recent trends in user studies: action research and qualitative methods

Directory of Open Access Journals (Sweden)

T.D. Wilson

1998-01-01

Full Text Available This paper was commissioned by Professor Gernot Wersig of the Freie Universität, Berlin in 1980, as part of his Project, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation. It attempted to set out what was, for the time, a novel perspective on appropriate methodologies for the study of human information seeking behaviour, focusing on qualitative methods and action research, arguing that the application of information research depended up its adoption into the managerial processes of organizations, rather than its self-evident relationship to any body of theory.

Multi-Locality Based Local and Symbiotic Computing for Interactively fast On-Demand Weather Forecasting for Small Regions, Short Durations, and Very High-Resolutions

OpenAIRE

Fjukstad, Bård

2014-01-01

Papers 1, 3 and 4 are not available in Munin: 1: Bård Fjukstad, Tor-Magne Stien Hagen, Daniel Stødle, Phuong Hoai Ha, John Markus Bjørndalen, and Otto Anshus: ‘Interactive Weather Simulation and Visualization on a Display Wall with Many-Core Compute Nodes’, in K. Jónasson (ed.): PARA 2010, Part I, LNCS 7133, pp. 142–151, 2012, © Springer-Verlag Berlin Heidelberg 3: Bård Fjukstad, John Markus Bjørndalen and Otto Anshus: ‘Accurate Weather Forecasting Through Locality Based Collaborative Computi...

Kes ikkagi asutas Pirita kloostri? / Kersti Markus

Index Scriptorium Estoniae

Markus, Kersti, 1962-

2012-01-01

Tegelik kloostri ülesehitaja oli Hinrich Swalbart. Kuna birgitiinide kloostrid allusid kohalikule piiskopile ning Swalbart oli kloostri rajamisega seotud alates 1405. aastast, siis võiks väita, et Pirita kloostri rajamise idee pärineb Saksa ordu kõrgmeistri Konrad von Jungingeni lähikonnast. Nimelt sai 1405. aastal Tallinna uueks piiskopiks Johannes III Aken, kes oli eelnevalt olnud ordu kõrgmeistri kaplan

Armin Tuulse ja kirikute uurimine / Kersti Markus

Index Scriptorium Estoniae

Markus, Kersti, 1962-

2008-01-01

Arhitektuuri- ja kunstiajaloolase tegevusest 1930. aastate Eestis ja Teise maailmasõja järgses Rootsis. Saksa ja rootsi teadlaste vahelistest kultuuriregiooni vaidlustest. Eesti kunsti omapära otsingutest. Keskaegse sakraalkunsti uurimise meetoditest

Markus Maeurer on the LifeGene project.

Science.gov (United States)

Maeurer, Markus

2010-09-01

This year will see the full-scale roll-out of the LifeGene study. Coordinated by the Karolinska Institutet (Stockholm, Sweden), the project looks set to be one of the largest health studies performed in the world, aiming to enroll 500,000 Swedes in order to determine the relationship between disease and environmental, lifestyle and hereditary factors. International experts from a broad spectrum of scientific fields will collaborate on this project, including Mark Maeurer, Chair of the infections working group in LifeGene (www.lifegene.se). Maeurer leads the additional study on influenza-like illnesses, which is currently being run within the LifeGene project. Maeurer studied medicine in Germany, Switzerland and the USA. He is board-certified in medical microbiology, has served as Assistant Professor of Surgery at the University of Pittsburgh Medical School (PA, USA) in the Department of Surgical Oncology and Immunotherapy, as Professor of Medical Microbiology at the University of Mainz, Germany, and is now Professor of Clinical Immunology at the Microbiology and Tumor Cell Biology Center at the Karolinska Institutet. Maeurer has conducted experiments with nonhuman primate models to study TB vaccine take, with the aim to profile markers of immune protection. His general interests are in the field of immune reconstitution and memory immune responses, with a particular focus on gauging protective T-cell responses and antibody immune signatures using high-content peptide microarrays. He has published more than 100 original articles, ten book chapters and serves as a reviewer for a number of international scientific journals.

Technical presentation: Next Generation Oscilloscopes

CERN Multimedia

PH Department

2011-01-01

  Rohde & Schwarz "Next Generation Oscilloscopes" - Introduction and Presentation Agenda: Wednesday 23 March  -  09:30 to 11:30 (open end) Bldg. 13-2-005 Language: English 09.30 Presentation "Next Generation Oscilloscopes" from Rohde & Schwarz RTO / RTM in theory and practice Gerard Walker 10.15 Technical design details from R&D Dr. Markus Freidhof 10.45 Scope and Probe Roadmap (confidential) Guido Schulze 11.00 Open Discussion Feedback, first impression, wishes, needs and requirements from CERN All 11.30 Expert Talks, Hands on All Mr. Dr. Markus Freidhof, Head of R&D Oscilloscopes, Rohde & Schwarz, Germany; Mr. Guido Schulze, ...

Det naturskønnes genkomst?

DEFF Research Database (Denmark)

Braae, Ellen

2008-01-01

the basis for a rediscovery of the specific aesthetic category 'natural beauty', which for a long time has been displaced from modern aesthetics, is the main concern of this article. Drawing on philosophers as Adorno, Ritter, Seel and both Hartmut and Gernot Böhme a discussion on the relational between...... the whole nature and the nature as a whole; between subject and object and the notion of atmosphere is carried out pointing at the nescessity of the reestablishment of a new aesthetic of nature. Based on the inner relation between 'the good' and 'the beautiful' ethics and aesthetics, the antigue notion...

Determination of absorbed dose calibration factors for therapy level electron beam ionization chambers.

Science.gov (United States)

McEwen, M R; Williams, A J; DuSautoy, A R

2001-03-01

Over several years the National Physical Laboratory (NPL) has been developing an absorbed dose calibration service for electron beam radiotherapy. To test this service, a number of trial calibrations of therapy level electron beam ionization chambers have been carried out during the last 3 years. These trials involved 17 UK radiotherapy centres supplying a total of 46 chambers of the NACP, Markus, Roos and Farmer types. Calibration factors were derived from the primary standard calorimeter at seven energies in the range 4 to 19 MeV with an estimated uncertainty of +/-1.5% at the 95% confidence level. Investigations were also carried out into chamber perturbation, polarity effects, ion recombination and repeatability of the calibration process. The instruments were returned to the radiotherapy centres for measurements to be carried out comparing the NPL direct calibration with the 1996 IPEMB air kerma based Code of Practice. It was found that, in general, all chambers of a particular type showed the same energy response. However, it was found that polarity and recombination corrections were quite variable for Markus chambers-differences in the polarity correction of up to 1% were seen. Perturbation corrections were obtained and were found to agree well with the standard data used in the IPEMB Code. The results of the comparison between the NPL calibration and IPEMB Code show agreement between the two methods at the +/-1% level for the NACP and Farmer chambers, but there is a significant difference for the Markus chambers of around 2%. This difference between chamber types is most likely to be due to the design of the Markus chamber.

KONSEP RUANG TERBUKA PUBLIK MAHASISWA SEBAGAI PENGHUBUNG ANTAR UNIT DI UNIVERSITAS TANJUNGPURA

Directory of Open Access Journals (Sweden)

Yudi Purnomo

2014-01-01

Zahnd, Markus. 2009.  Pendekatan dalam Perancangan Arsitektur: Metode untuk Menganalisis dan Merancang Arsitektur secara Efektif.Penerbit Kanisius, Semarang: Soegijapranata University Press, Yogyakarta

Outstanding Problems in Solar Physics Markus J. Aschwanden

Indian Academy of Sciences (India)

Self-organized criticality (from nanoflares to giant flares). 8. Magnetic ... liantly confirmed the theory ofneutrino (flavor) oscillations, and this way also corrobo- rated the ... On the other side, experimental verification has been achieved with high ...

Twilio Eesti büroo = Offices of Twilio Estonia / Katrin Kaevats ; kommenteerinud Ann Koljang

Index Scriptorium Estoniae

Kaevats, Katrin, 1980-

2016-01-01

Rahvusvahelise ettevõtte Twilio Eesti büroo Tallinnas, Veerenni tn. 24. Sisekujunduse autorid Katrin Kaevats, Jaan Port, Markus Nimik, Neeme Tiimus, Anna Nikland. Büroohoone projekteerisid PIN Arhitektid

Prada postulaat = Prada Postulate / Martin Melioranski

Index Scriptorium Estoniae

Melioranski, Martin

2002-01-01

Hollandi arhitektide Rem Koolhaasi ja Ole Scheereni (Office for Metropolitan Architecture) projekteeritud Prada kauplusest SoHos New Yorgis. Infotehnoloogia: R. Koolhaas ja Markus Schaefer (AMO-Information technology). 13 ill.

Star Wars als bron van religie : Voorbeeld van een lessenserie in bovenbouw havo/vwo

NARCIS (Netherlands)

Ouden, den J.A.J.; Davidsen, M.A.

2017-01-01

Voorbeeldlessen bij Davidsen, Markus Altena & Jeannette den Ouden (2016), “Star Wars in het religieonderwijs: Religiekunde in de lespraktijk I”, Narthex: tijdschrift voor levensbeschouwing en educatie 16(2), 64-71.

Pärnu Keskraamatukogu = Pärnu Central Library / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2009-01-01

Raamatukoguhoone arhitektid Andres Ojari, Ilmar Valdur, Markus Kaasik, Kalle Komissarov ja Mihkel Tüür pälvisid Eesti Kultuurkapitali 2008. aasta peapreemia. Hoone arhitektuursest lahendusest, žürii hinnang hoonele

Aaviku Housing, Tallinn

Index Scriptorium Estoniae

2005-01-01

Arhitektibüroo Emil Urbel OÜ projekteeritud Tallinna Aaviku elamurajoon märgiti ära arhitektuurikonkursil "Parim Euroopas - värv". Eestist kuulus nominente esitanud žüriisse arhitekt Markus Kaasik

Vana hea arhitektuur : Villa-V Nõmmel = Good Old Architecture : Villa-V in Nõmme / Siiri Vallner

Index Scriptorium Estoniae

Vallner, Siiri, 1972-

2001-01-01

Projekteerija: arhitektibüroo Kolm Pluss Üks. Arhitektid Markus Kaasik, Andres Ojari, Ilmar Valdur. Projekt 1998, valmis 2001. 11 ill.: pindade diagramm, korruste plaanid, lõige, sise- ja välisvaated

Republication of: New solutions to Einstein's equations of gravitation. B. Explicit determination of static, axially symmetric fields. By Rudolf Bach. With a supplement on the static two-body problem. By H. Weyl.

Science.gov (United States)

Bach, Rudolf; Weyl, Hermann

2012-03-01

This is the English translation of the third of a series of 3 papers by Hermann Weyl (the third one jointly with Rudolf Bach), first published in 1917-1922, in which the authors derived and discussed the now-famous Weyl two-body static axially symmetric vacuum solution of Einstein's equations. The English translations of the other two papers are published alongside this one. The papers have been selected by the Editors of General Relativity and Gravitation for re-publication in the Golden Oldies series of the journal. This republication is accompanied by an editorial note written by Gernot Neugebauer, David Petroff and Bahram Mashhoon, and by a brief biography of R. Bach, written by H. Goenner.

Technical Note: Scanning of parallel-plate ionization chamber and diamond detector for measurements of water-dose profiles in the vicinity of a narrow x-ray microbeam.

Science.gov (United States)

Nariyama, Nobuteru

2017-12-01

Scanning of dosimeters facilitates dose distribution measurements with fine spatial resolutions. This paper presents a method of conversion of the scanning results to water-dose profiles and provides an experimental verification. An Advanced Markus chamber and a diamond detector were scanned at a resolution of 6 μm near the beam edges during irradiation with a 25-μm-wide white narrow x-ray beam from a synchrotron radiation source. For comparison, GafChromic films HD-810 and HD-V2 were also irradiated. The conversion procedure for the water dose values was simulated with Monte Carlo photon-electron transport code as a function of the x-ray incidence position. This method was deduced from nonstandard beam reference-dosimetry protocols used for high-energy x-rays. Among the calculated nonstandard beam correction factors, P wall , which is the ratio of the absorbed dose in the sensitive volume of the chamber with water wall to that with a polymethyl methacrylate wall, was found to be the most influential correction factor in most conditions. The total correction factor ranged from 1.7 to 2.7 for the Advanced Markus chamber and from 1.15 to 1.86 for the diamond detector as a function of the x-ray incidence position. The water dose values obtained with the Advanced Markus chamber and the HD-810 film were in agreement in the vicinity of the beam, within 35% and 18% for the upper and lower sides of the beam respectively. The beam width obtained from the diamond detector was greater, and the doses out of the beam were smaller than the doses of the others. The comparison between the Advanced Markus chamber and HD-810 revealed that the dose obtained with the scanned chamber could be converted to the water dose around the beam by applying nonstandard beam reference-dosimetry protocols. © 2017 American Association of Physicists in Medicine.

Advances in ontologies, proceedings of the Australasian ontology workshop, Melbourne, Australia

CSIR Research Space (South Africa)

Meyer, T (ed)

2009-12-01

Full Text Available Iannella Ken Kaneiwa C. Maria Keet Kevin Lee Laurent Lefort Constantine Mantratzis Lars Moench Deshendran Moodley Mehmet Orgun Maurice Pagnucco Debbie Richards Rolf Schwitter Murat Sensoy Barry Smith Markus Stumptner Boontawee...

Europäische exekutive Rechtsetzung zwischen Kommission, Komitologieausschüssen, Parlament und Rat / Gernot Sydow

Index Scriptorium Estoniae

Sydow, Gernot

2012-01-01

Euroopa Liidu määrusest (EL 182/2011), millega kehtestatakse eeskirjad ja üldpõhimõtted, mis käsitlevad liikmesriikide läbiviidava kontrolli mehhanisme, mida kohaldatakse komisjoni rakendamisvolituste teostamise suhtes

Stiilne kahetoaline stuudiokorter / Sanna Vatanen

Index Scriptorium Estoniae

Vatanen, Sanna

2007-01-01

Infoturvajuhi Markus Porvari renoveeritud korter (71 m2) Helsingi kesklinnas 1925. a. ehitatud majas. Korteris on tipptasemel HI-FI tehnika. Vannitoa, sauna ja tualettruumi kavandas Jukka Airas firmast Airas Design. 7. värv. vaadet

Evident in Advance: the maze of translations / Merilin Talumaa, Marie Vellevoog

Index Scriptorium Estoniae

Talumaa, Merilin, 1986-

2013-01-01

Dénes Farkasi projektist "Evident in Advance", mis esindab Eestit 55. Venezia biennaalil. Kuraaror Adam Budak, näituse arhitekt Markus Miessen, disainerid Grégory Ambos ja Zak Keys. Eesti paviljoni komissar Maria Arusoo

Plaadid / Priit Juurmann

Index Scriptorium Estoniae

Juurmann, Priit

2006-01-01

Uutest heliplaatidest Markus Enochson "Night Games ئ In Steps And Sequences", Up Hygh "The Venus Album", Oasis "Stop the Clock", The Who "Endless Wire", Ray Lamantagne "Trouble", Take That "Beautiful World", Danolo Venturi "La Perla: Noir"

Hea nali võib peituda raamatus / Gert Kiiler

Index Scriptorium Estoniae

Kiiler, Gert

2007-01-01

Arvustus: Leer, Jaak. Savumees Einaril on kogu aeg buss katki. Tallinn : Jutulind, 2006 ; Huber, Markus, Treichler, Robert. Keegi pole nii vinge kui meie : uimased britid, tobedad sakslased, pinges prantslased ja veel 36 lootusetut juhtumit. Tallinn : Olion, 2006

Novosti modõ / Jevgenija Fedorovskaja

Index Scriptorium Estoniae

Fedorovskaja, Jevgenija

2001-01-01

Kõrgmoenädalast Londonis - muudatusi seoses terroriaktiga New Yorgis. Jasper Conrani, Oscar de la Renta, Markus Lüpferi, John Rocha, Londoni kunstnike-dueti Blaak (pärit Lõuna-Aafrikast) kollektsioonidest ja poola kunstniku Arkadiuse art-objektide esitlusest

African Zoology - Vol 4, No 1 (1969)

African Journals Online (AJOL)

The haematoza of South African birds. III. The carmine bee-eater Merops Nubicoides Des Murs and Pucheran · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JH Oosthuizen, MB Markus ...

Tartlased andsid oma panuse elamise kunsti / Krista Piirimäe

Index Scriptorium Estoniae

Piirimäe, Krista, 1946-

2007-01-01

Eesti Kunstnike Liidu aastanäitusest "Elamise kunst" Tallinna Kunstihoones. Pikemalt Ilmar Kruusamäe, Markus Kasemaa, Saskia Kasemaa, Andrus Kasemaa, Silver Vahtre, Anne Parmasto, Meiu Mündi, Tiiu Kirsipuu näitusel eksponeeritud töödest

Mormoonid võõrustavad olümpiat / Heiki Suurkask

Index Scriptorium Estoniae

Suurkask, Heiki, 1972-

2002-01-01

Taliolümpiamängude linn Salt Lake City on pooleteise sajandiga kasvanud väikesest mormoonide asulast kümne miljoni mormooni maailmapealinnaks. Kaart : Utah osariik. Lisa : Markus Larsson. Toretsev, salapärane ja võimas usulahk

Parties now talk about the EU in national election campaigns, but they still tend to talk past each other

DEFF Research Database (Denmark)

Senninger, Roman; Wagner, Markus

2015-01-01

How important is the issue of European integration to national election campaigns? Roman Senninger and Markus Wagner write that while the EU previously played only a very small role in national elections, the onset of the Eurozone crisis has resulted in the issue becoming more prominent in campai......How important is the issue of European integration to national election campaigns? Roman Senninger and Markus Wagner write that while the EU previously played only a very small role in national elections, the onset of the Eurozone crisis has resulted in the issue becoming more prominent...... in campaigns in several countries. However, using an analysis of party press releases in Austria, they illustrate that parties still differ greatly in how they address the issue, with parties exhibiting a tendency to talk past each other rather than genuinely engaging with the subject....

Pärnu raamatukogu = Pärnu Library

Index Scriptorium Estoniae

2009-01-01

Pärnu Keskraamatukogu hoonest, mille autorid on Markus Kaasik, Andres Ojari, Ilmar Valdur, Kalle Komissarov ja Mihkel Tüür, projekteerija Kolm Pluss Üks, konstruktor Pike. Projekt 2001, valmis: 1. etapp - 2003, 2. etapp - 2008. Lisa: Ehituslugu 1999-2009

Eesti Lähimineviku Okupatsioonide Muuseumi arhitektuurivõistlus : okupatsiooni igaveseks jäädvustamiseks = Architectural Competition of the Museum of Recent Past Occupations in Estonia : for Eternal Remembrance of the Occupation / Leonhard Lapin

Index Scriptorium Estoniae

Lapin, Leonhard, 1947-

2001-01-01

Zürii koosseis, võistlusest, võidutööst. Preemiad: I - Indrek Peil, Siiri Vallner; II - Tiina Teng, Peeter Loo; III - Reio Avaste; ostud - Andres Kask ning Markus Kaasik, Kalle Komissarov, Andres Ojari, Indrek Tiigi ja Ilmar Valdur. 5 ill.

E-piima Põltsamaa Meierei juustumuuseum = E-Piim Põltsamaa Dairy Cheese Museum

Index Scriptorium Estoniae

2004-01-01

Pealeehitus tootmishoonele. Juustutööstust eksponeeritakse läbi laeakende ning multimeedia ja graafiliste vahendite abil seintel ja kaldtasandil. Projekteerija: 3+1 arhitektid. Autorid Markus Kaasik, Kalle Komissarov, Andres Ojari, Ilmar Valdur. Konstruktor Tõnu Peipmann. Projekt 2001. 11 ill

Fiction and Religion : How Narratives About the Supernatural Inspire Religious Belief

NARCIS (Netherlands)

Davidsen, M.A.

2016-01-01

Thematic issue on 'Fiction and Religion: How Narratives About the Supernatural Inspire Religious Belief', volume 46(4) of Religion. The thematic issue inclues the following articles: Davidsen, Markus Altena, "Fiction and Religion: How Narratives About the Supernatural Inspire Religious Belief –

A study of the woman in the crowd and her desperate courage (Mark 5:21–43

Directory of Open Access Journals (Sweden)

Robin G. Branch

2013-07-01

Full Text Available This article examines the cameo appearance of an unnamed woman in the gospel of Mark, a member of a crowd following Jesus (Mk 5:24b–34. Chronically ill and probably dying, she thinks she is inconspicuous. The text identifies her in terms of her gender, illness, covenant status, prolonged suffering and penury. Yet, a careful reading reveals her stealth, desperation, courage and eloquence − all elements of character and, it turns out, of a faith focused on Jesus. Combining both literary and canonical insights, this article shows how the story of the anonymous woman, set within the larger context of the healing of Jairus’ daughter, sheds light on the developing concepts of faith, fear, purity, discipleship, confession and family matters in Mark. The woman’s interaction with Jesus adds depth to Mark’s portrait of him and contributes to the ongoing revelation in Mark that Jesus is indeed the Son of God (Mk 1:1. Hierdie artikel ondersoek die reliëfverskyning van ’n naamlose vrou in die evangelie van Markus. Sy was deel van die skare wat Jesus gevolg het (Mark 5:24b–34. Omdat sy kronies siek en moontlik sterwend was, het sy gedink sy is onopvallend in die skare. Sy word in die teks geïdentifiseer in terme van haar geslag, siekte, verbondstatus, langdurige lyding en armoedige voorkoms. ’n Noukeurige bestudering van die gedeelte openbaar ook haar heimlikheid, desperaatheid, moed en welsprekendheid – alles eienskappe van ’n sterk karakter en, soos dit later blyk, haar gefokusde geloof op Jesus. Deur die letterkundige en kanonieke insigte te kombineer, wys die artikel hoe die verhaal van die anonieme vrou, gesien teen die agtergrond van die genesing van Jaïrus se dogtertjie, lig werp op die ontwikkelende konsepte van geloof, vrees, suiwerheid, dissipelskap, belydenis en familie-aangeleenthede in die boek Markus. Die vrou se interaksie met Jesus verskaf diepte aan Markus se uitbeelding van Hom en maak ’n bydrae tot Markus se

Jalutades Koidula tänava aias = A walk on the grounds of the Koidula building / Veronique Faucheur

Index Scriptorium Estoniae

Faucheur, Veronique

2006-01-01

Aed Tallinnas Koidula tänava korterelamu siseõues. Elamu projekteeris AB Kolm Pluss Üks. Autorid: Markus Kaasik, Andres Ojari, Ilmar Valdur. Aia projekt: atelier le balto. Aia autorid: Veronique Faucheur, Marc Pouzol. Projekt 2005, valmis 2006. Ill.: aia plaan, 6 vaadet

Kalevipoeg ja Mumm-Summ VAT Teatri moodi

Index Scriptorium Estoniae

2003-01-01

VAT Teatris esietendub 5. dets. M. Kampuse lavastatud jõuluetendus "Lihtsalt ... Mesilane" C. Vogli lugude "Väike mesilane Mumm-Summ" ainetel. VAT Teatri ja Markus Zohneri koostööprojektina esietendus 30. nov. Tallinna Linnateatris rahvuseepose "Kalevipoeg" motiividel loodud M. Zohneri lavaversioon

Melatonin modulates rat myotube-acetylcholine receptors by inhibiting calmodulin.

Science.gov (United States)

de Almeida-Paula, Lidiana Duarte; Costa-Lotufo, Leticia V; Silva Ferreira, Zulma; Monteiro, Amanda Elisa G; Isoldi, Mauro Cesar; Godinho, Rosely O; Markus, Regina P

2005-11-21

Melatonin, the pineal gland hormone, modulates alpha-bungarotoxin sensitive nicotinic acetylcholine receptors in sympathetic nerve terminals, cerebellum and chick retina imposing a diurnal variation in functional responses [Markus, R.P., Zago, W.M., Carneiro, R.C., 1996. Melatonin modulation of presynaptic nicotinic acetylcholine receptors in the rat vas deferens. J. Pharmacol. Exp. Ther. 279, 18-22; Markus, R.P., Santos, J.M., Zago, W., Reno, L.A., 2003. Melatonin nocturnal surge modulates nicotinic receptors and nicotine-induced [3HI] glutamate release in rat cerebellum slices. J. Pharmacol. Exp. Ther. 305, 525-530; Sampaio, L.F.S., Hamassaki-Britto, D.E., Markus, R.P., 2005. Influence of melatonin on the development of functional nicotinic acetylcholine receptors in cultured chick retinal cells. Braz. J. Med. Biol. Res. 38, 603-613]. Here we show that in rat myotubes forskolin and melatonin reduced the number of nicotinic acetylcholine receptors expressed in plasma membrane. In addition, these cells expressed melatonin MT1 receptors, which are known to be coupled to G(i)-protein. However, the pharmacological profile of melatonin analogs regarding the reduction in cyclic AMP accumulation and number of nicotinic acetylcholine receptors did not point to a mechanism mediated by activation of G(i)-protein coupled receptors. On the other hand, calmidazolium, a classical inhibitor of calmodulin, reduced in a similar manner both effects. Considering that one isoform of adenylyl cyclase present in rat myotubes is regulated by Ca2+/calmodulin, we propose that melatonin modulates the number of nicotinic acetylcholine receptors via reduction in cyclic AMP accumulation.

¿CONTINGENCIA O NECESIDAD? SCHELLING Y HEGEL ACERCA DEL ESTATUS MODAL DEL ESPACIO LÓGICO

Directory of Open Access Journals (Sweden)

Markus Gabriel

2010-01-01

Full Text Available Palabras pronunciadas por Markus Gabriel en el marco del encuentro internacional "Presente del idealismo alemán" organizado por el Departamento de Filosofía de la Universidad Nacional de Colombia. Conferencia que tuvo lugar el 9 de octubre de 2009.

Disease: H01046 [KEGG MEDICUS

Lifescience Database Archive (English)

Full Text Available ... TITLE ... Efficacy of albendazole against the whipworm trichuris trichiura--a randomised, controlled trial. ... JOURNAL ... S Afr Med J 94:972-6 (2004) ...0-6736(06)68653-4 ... PMID:15662995 (drug) ... AUTHORS ... Adams VJ, Lombard CJ, Dhansay MA, Markus MB, Fincham JE

From Perceptual Apparatus to Immersive Field of Experience

DEFF Research Database (Denmark)

Wieczorek, Izabela

2014-01-01

Peter Sloterdijk ascribes to architecture the “the design of immersions” and hence the “production of embedding situations” or atmosphere (2011 (2006): 108-109), which as devised by Gernot Böhme becomes a fundamental concept of a new aesthetics (1993). Atmosphere implies affective immersion...... the immersive experiences relocate the vision within a “carnal density” (1992: 150), regaining all sensory modalities. Diverse perceptual apparatuses also defined a larger disciplinary expansion in the field of architecture and design. Conceived as sensorial activators, intensifiers of phenomena......, constitute a framework for a re-invention of perceptual worlds, providing a basis for tracing the conceptual contours of atmospheric perception, as well as for discerning the means of the production of space understood as an immersive field of experience. References: Böhme, G. (1993). "Atmosphere...

Markus 1:4 in die Nuwe Aftikaanse Vertaling | Thom | HTS ...

African Journals Online (AJOL)

... forgiveness and sins) which is foreign to many modern languages. In this paper the way the New Afrikaans Bible translates these words is analysed and evaluated. It is concluded that the New Afrikaans Bible's (1983) translation of this verse has been influenced by dogmatic concerns rather than linguistic considerations.

Eesti-Läti orienteerumisliiga kaardistajate seminar Kanepis / koostanud Markus Puusepp

Index Scriptorium Estoniae

2010-01-01

Projekti teisest kaardistajate seminarist, mis toimus 30.-31. oktoobril Põlvamaal Kanepis. Vaata ka http://spordilinn.blogspot.com/2010/11/eesti-vs-lati-moned-motted.html ja http://orienteerumine.ee/estlat/seminarid/

Solar Flare Physics Enlivened by TRACE and RHESSI Markus J ...

Indian Academy of Sciences (India)

the highest EUV spatial resolution and the Ramaty High Energy Solar Spec- trometric Imager ... Displaced Electron and Ion Acceleration Sources. Key words. ... 2002) and the solid-state detectors of the Soft ... new diagnostic of the flare plasma temperature and iron abundance. 3. .... from the thick-target model (Fig. 3, right ...

When Diversity Training Isn’t Enough: The Case for Inclusive Leadership

Science.gov (United States)

2013-08-06

O’Reilly, 1992). Furthermore, demographic diversity (e.g., sex , gender, and age) has been associated with increased turnover, increased conflict...in the workplace. Journal of Hospitality and Tourism Research, 35, 469–487. Markus, H. R., Steele, C. M., & Steele, D. M. (2000). Colorblindness as a

Asset Reuse of Images from a Repository

Science.gov (United States)

Herman, Deirdre

2014-01-01

According to Markus's theory of reuse, when digital repositories are deployed to collect and distribute organizational assets, they supposedly help ensure accountability, extend information exchange, and improve productivity. Such repositories require a large investment due to the continuing costs of hardware, software, user licenses, training,…

Cultural self-construals of Mexican, Spanish, and Danish college students: Beyond independent and interdependent self

DEFF Research Database (Denmark)

Santamaría, Andrés; de la Mata, Manuel L.; Hansen, Tia G. B.

2010-01-01

De sidste par tiår har tværkulturel forskning vist vigtige forskelle i selvbegribelse. En dybere forståelse forudsætter imidlertid inddragelse af flere kulturer. Modsat Markus og Kitayamas distinktion mellem independent og interdependent selv, har forfattere som Kagitcibasi m.fl. argumenteret for...

Treatment Integrity Enhancement via Performance Feedback Conceptualized as an Exercise in Social Influence

Science.gov (United States)

Erchul, William P.

2013-01-01

This commentary is in response to the article "Effects of Verbal and Written Performance Feedback on Treatment Adherence" (Kaufman, Codding, Markus, Tryon, & Kyse, this issue). The overall recommendation to those who study treatment integrity using performance feedback methods is to incorporate theories and research on social…

Genetics Home Reference: desmosterolosis

Science.gov (United States)

... 2001 Aug 22. Citation on PubMed or Free article on PubMed Central Zolotushko J, Flusser H, Markus B, Shelef I, Langer Y, Heverin M, Björkhem I, Sivan S, Birk OS. The desmosterolosis phenotype: spasticity, microcephaly and micrognathia with agenesis of corpus callosum and ...

ISOTDAQ School: one of a kind

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Particle physics research has many unique needs and sometimes has to create its own expertise to keep its systems running. For specialised areas like cryogenics and high-voltage technology, labs often run their own training courses. In line with this trend, CERN has started a series of International Trigger and Data Acquisition (ISOTDAQ) Schools. 2012 has seen the third ISOTDAQ School, which generated a lot of enthusiasm among the future generation of TDAQ experts.   Markus Joos tutoring a group of students. “Can I call you back in about an hour? I’m just in the middle of tutoring a group of four students in one of our practical sessions,” says Markus Joos, one of the organisers, when we call him to ask some questions about the current ISOTDAQ School taking place in Cracow, Poland, from 1 to 8 February. He later explains that half of the teaching time at the School is dedicated to such practical sessions, where students complete exercises using computers, elect...

ON THE RESPONSE OF IMPACTING COMPLIANT FLEX RUN

African Journals Online (AJOL)

user

ON THE RESPONSE OF IMPACTING COMPLIANT FLEX RUN. T. T. Akano1,* and ... different from traditional rigid-body mechanisms which have rigid links ... components such as wings, fan blades and containment casings[6] ... Figure 2: Germany's Markus Rehm jumps at the Muller ... the principal stretches j as. , ,. [∑.

Vastutada lustides ja vastupidi / interv. Eva-Liisa Linder

Index Scriptorium Estoniae

2006-01-01

Lavakunstikooli XXII lend räägib kooliajast, õpetajatest ja õppetööst. Kõnelevad Mihkel Kabel, Martin Kõiv, Risto Kübar, Lauri Lagle, Tõnn Lamp, Mari-Liis Lill, Markus Luik, Ragne Pekarev, Laura Peterson, Ursula Ratasepp, Inga Salurand, Veiko Tubin, Nero Urke, Britta Vahur ja Sergo Vares

Using artificial neural network approach for modelling rainfall–runoff ...

Indian Academy of Sciences (India)

Department of Civil Engineering, National Pingtung University of Science and Technology, Neipu Hsiang,. Pingtung ... study, a model for estimating runoff by using rainfall data from a river basin is developed and a neural ... For example, 2009 typhoon Morakot in Pingtung ... Tokar and Markus (2000) applied ANN to predict.

Reference: 163 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 163 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u15660207i Kanter Ulr...saccharides. 2 243-54 15660207 2005 May Planta Guerineau Fran巽ois|Kanter Ulrike|Li Yong|Pauly Markus|Tenhaken Raimund|Usadel Bj旦rn

Kas Hiina draakon õpib ka lendama? / Villu Zirnask

Index Scriptorium Estoniae

Zirnask, Villu, 1966-

2011-01-01

Uuringust, mille käigus püüti välja selgitada Hiina patendistrateegiat. (Markus Eberhardt, Christian Helmers, Zhihong Yu. Is the dragon learning to fly? An analysis of the Chinese patent explosion. (CSAE Working Paper WPS/2011-15). Tabel: USA-s enim patente registreerinud Hiina ettevõtted (1985-2006)

Saturation mapping of QTL region determining resistance specificity ...

African Journals Online (AJOL)

STORAGESEVER

2009-09-01

Sep 1, 2009 ... S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J,. Hong G, Xue Y, Han B ... Katagiri F, Markus Lange B, Moughamer T, Xia Y, Budworth P,. Zhong J, Miguel T, ... Gen. Genet. 261: 58-63. Marrs KA (1996).

Kolmest Tallinna Ülikooli Humboldti stipendiaadist / Tiina Tamkivi

Index Scriptorium Estoniae

Tamkivi, Tiina

2014-01-01

Tallinna Ülikooli külastas jaanuaris teadlasi toetava fondi Alexander von Humboldt Stiftung president ja Berliini Tehnikaülikooli keemiaprofessor Helmut Schwarz. Tallinna Ülikoolist on Humboldti stipendiumi pälvinud kolm teadlast - professor Peeter Järvelaid, ajaloolane Juhan Kreem ja kunstiajaloolane Kersti Markus, kes lisavad artiklis ka omapoolsed selgitused

Case note: CJEU (Synthetic marijuana not a "medicinal product")

NARCIS (Netherlands)

Luzak, J.

2014-01-01

Joined Cases C-358/13 and C-181/14, Markus D. and G. Substances which produce effects that merely modify physiological functions but which are not such as to have any beneficial effects, either immediately or in the long term, on human health, are consumed solely to induce a state of intoxication

The Benefits and Limitations of Formality

Science.gov (United States)

Kane, Michael

2008-01-01

Michael Kane comments on three articles in this issue: (1) "Is Psychometrics Pathological Science?" (Joel Mitchell); (2) "Latent Variable Theory" (Denny Borsboom); and (3) "Constructs, Concepts, and the Worlds of Possibility" (Keith Markus). He states that the common thread in these three articles is the goal of putting measurement practice on a…

Inglismaal jagati taas D&AD auhindu

Index Scriptorium Estoniae

2008-01-01

Keskkonnakujunduse kategoorias tõsteti 2007. a. esile: Heathrow Terminal 5 klubi (arhitektid Chris Bagot, Oliver Salway, disainerid Joe Ferry, Emma Lally, Monique van der Hurk, Hillary Clark jt.), Lohringi metroojaam Bohumis (Rübsamen & Partner, kunstnikud Eva-Maria Joeressen, Klaus Kessner), kauplus Freitag Zürichis (arhitektid Harald Echsle, Annette Spillmann, disainerid Daniel ja Markus Freitag)

Verification of the absorbed dose values determined with plane parallel ionization chambers in therapeutic electron beams using ferrous sulfate dosimetry

International Nuclear Information System (INIS)

Plaetsen, A. van der; Thierens, H.; Palmans, H.

2000-01-01

Absolute and relative dosimetry measurements in clinical electron beams using different detectors were performed at a Philips SL18 accelerator. For absolute dosimetry, ionization chamber measurements with the PTW Markus and PTW Roos plane parallel chambers were performed in water following the recommendations of the TRS-381 Code of Practice, using different options for chamber calibration. The dose results obtained with these ionization chambers using the electron beam calibration method were compared with the dose response of the ferrous sulphate (Fricke) chemical dosimeter. The influence of the choice of detector type on the determination of physical quantities necessary for absolute dose determination was investigated and discussed. Results for d max , R 50 and R p were in agreement within statistical uncertainties when using a diode, diamond or plane parallel chamber. The effective point of measurement for the Markus chamber is found to be shifted 0.5 mm from the front surface of the cavity. Fluence correction factors, h m , for dose determination in electron beams using a PMMA phantom were determined experimentally for both plane parallel chamber types. (author)

Changing Europe, changing self-construals

DEFF Research Database (Denmark)

Antalikova, Radka

Self-construal refers to the culturally shaped view on self, and in particular the degree of inclusion of other people in one’s self-definition (Markus & Kitayama, 1991) whether in form of close relationships or important group memberships. The degree of including these social variables distingui......Self-construal refers to the culturally shaped view on self, and in particular the degree of inclusion of other people in one’s self-definition (Markus & Kitayama, 1991) whether in form of close relationships or important group memberships. The degree of including these social variables...... country, college students and their parents, to fill out a shortened version of Twenty Statements Test (Kuhn & McPartland, 1959). This self-description questionnaire detects prevailing views on self (private, public, or collective), as described above. Both Danish generations have lived in a more or less...... similar socio-cultural discourse. The older generation in Slovakia has lived in two very different political regimes, and Slovak adolescents have direct experience with only the post-communist version. Thus, we employed these four samples (two generations by two countries) to test for a greater...

Benaderings tot die interpretasie van die wonderverhale in Markus 8-10

Directory of Open Access Journals (Sweden)

G. J. van Wyk

2009-07-01

Full Text Available Approaches to the interpretation of miracle stories in Mark 8-10 Research on the miracle stories in Mark 8-10 and their role in this Gospel is discussed. The mythological, religious-historical, form-historical, Biblical-theological, redaction-historical, socio- logical, literary-critical, the research of Van der Loos and Brown, salvation-historical and revelation-historical research are discussed. Research shows that the kingdom of God, a paradoxal Christology and discipleship play an important role in the miracles and miracle stories in the Gospel of Mark. Miracles form an integral part of the gospel and ministry of Jesus. They serve to support the teaching of Jesus.

Tehissüda päästis surija elu / Markus Larsson

Index Scriptorium Estoniae

Larsson, Markus

2001-01-01

Esimese täielikult inimkehasse opereeritava alalise kunstliku plastmassist ja titaanist asendussüdame sai mees, kelle nime ja päritolu ei avalikustata, üleeile Kentuky osariigis Louisvilles Jewish Hospitalis

Culture and Social Psychology: Converging Perspectives

Science.gov (United States)

Dimaggio, Paul; Markus, Hazel Rose

2010-01-01

Views of culture in psychology and sociology have converged markedly in the past two decades. Both have rejected what Adams and Markus (2004) refer to as the "entity" conception of culture--the view that culture is coherent, stable, and located in the heads of collectivities' members--in favor of more supple and dynamic constructs. Culture, in…

Wiiralt plaadiümbrisel

Index Scriptorium Estoniae

2008-01-01

Ilmus progerockansambli King Krimsoni praeguse trummari Pat Mastelotto ja Saksa multiinstrumentalisti Markus Reuteri kahemehebändi Tuner kolmas album "Müüt", mis on salvestatud möödunud aasta oktoobris Tallinnas, Tartus ja Viljandis Jazzkaare kontsertidel. Plaadi ümbrise kujunduses on baski päritolu disainer Ritxi Ostariz kasutanud mitmeid Eduard Wiiralti tuntud töid Kumu kogudest

Auswirkungen der Zugänglichkeit independenten und interdependenten Selbstwissens auf den Selbstwert

OpenAIRE

Birkner, Norbert

2003-01-01

In drei Studien werden Befunde vorgelegt, die dafür sprechen, dass der Selbstwert von Personen mit independentem Selbstkonzept anders generiert wird als von Personen mit interdependentem Selbstkonzept, genauer sich aus unterschiedlichen Quellen speist. Innerhalb der drei Untersuchungsstichproben erfolgte die Klassifizierung der differenzierten Selbstkonstruktionen, die idealtypisch in individualistischen und kollektivistischen Kulturen entwickelt werden (Markus & Kitayama, 1991), auf Grundlag...

Affective Architecture. Film as a Sensory Transference Tool and an Intimacy Projection Environment

DEFF Research Database (Denmark)

Petersen, Rikke Munck; Farsø, Mads

2016-01-01

, with our bodies, perceive space and project space. Through an analysis of two films, it points to the medium of film as both a tool and an environment, based on Gernot Böhme’s ‘Raum leiblicher Anwesenheit (Böhme 2006). These films illustrate how the film’s picture frame becomes almost like a skin......This paper elucidates how film may offer itself as a tool for both the representation and conception of space that can strengthen an alternative, phenomenological and transcendental position in architecture. The paper underscores that the film camera can work as a kind of amplifier of how we...... and through its surface and sound projects both a site and a near-sensual experience simultaneously. The medium of film as both tool and an environment thereby supports an extended sensory-intimate reflection on outer experiences and inner sensations that – in its audio-visual and time...

Stochastic Analysis and Applied Probability(3.3.1): Topics in the Theory and Applications of Stochastic Analysis

Science.gov (United States)

2015-08-13

Critical Catalyst Reactant Branching Processes with Controlled Immigration , Annals of Applied Probability (03 2012) Amarjit Budhiraja, Rami Atar ...Markus Fischer. Large Deviation Properties of Weakly Interacting Processes via Weak Convergence Methods, Annals of Probability (10 2010) Rami Atar ...Dimensional Forward-Backward Stochastic Differen- tial Equations and the KPZ Equation Electron. J. Probab., 19 (2014), no. 40, 121. [2] R. Atar and A

Dual Optical Comb LWIR Source and Sensor

Science.gov (United States)

2017-10-12

Justin M. Brown, Mark G. Allen Physical Sciences Inc. (PSI) Pierre Jouy, Jérôme Faist Swiss Federal Institute of Technology (ETH) Markus Geiser...Research, Development & Engineering Center Name of Contractor: Physical Sciences Inc. Principal Investigator: Dr. Joel M. Hensley Business...including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and

The World of Organic Agriculture – Statistics and Emerging Trends (Session at the BIOFACH 2015)

OpenAIRE

Arbenz, Markus; Willer, Helga; Lernoud, Julia; Huber, Beate; Amarjit, Sahota

2015-01-01

The World of Organic Agriculture – Statistics and Emerging Trends (Session at the BIOFACH 2015) Presentations - Introduction (Markus Arbenz) - Organic Agriculture Worldwide: Current Statistics (Helga Willer, Julia Lernoud) - The World of Organic Agriculture: Regulations and Certification Emerging Trends 2015 (Beate Huber, Christiane Mannigel) - Global survey on Voluntary Sustainability Standards (VSS) (Julia Lernoud, Helga Willer) - Global Organic Food & Drink: Market Update...

Tallinna XIII graafikatriennaali grand prix' pälvis leedu graafik Egle Kuckaite

Index Scriptorium Estoniae

2004-01-01

Kolm võrdset preemiat: Sang-gon Chung Lõuna-Koreast, Krishs Salmanis Lätist ja Joanne Soroka Shotimaalt. Diplomid: Anonymous Boh ja Eve Kiiler Eestist, Pete Nevin Inglismaalt, Hanna Oinonen Soomest ja venetsueela-soome kunstnik Sandra Vina de Karila. Tallinna linna preemia: John Smith (Marko Mäetamm & Kaido Ole) Eestist. Eesti Kunstimuuseumi preemia: Markus Lampinen Soomest. Eesti Panga preemia: Leonards Laganovskis Lätist

The Use of Lens Shielding Device(L.S.D.) for a Conjunctival Lymphoma

Energy Technology Data Exchange (ETDEWEB)

Cho, Hyun Sang; Ju, Sang Gyu; Song, Ki Won; Park, Young Hwan [Dept. of Radition Oncology, Samsung Medical Center, Seoul (Korea, Republic of)

1997-11-15

When therapeutic irradiation is indicated for the orbital tumors, the greatest concern is the risk of radiation-induced cataract. Conjunctival lymphoma is one of the good examples. We would like to report the procedure of the lens shielding device(L.S.D) and the result of irradiated dose to the lens. L.S.D. consists of two parts : load alloy to attenuate electron beam, and dental acryl which completely covers the lead alloy to avoid discomfort of cornea from contacting directly with cerrobend and side scattering by cerrobend. And for easy location and removal, side bars were made on each side. Radiation doses were measured with TLD (TLD 3500 Hawshaw). Markus chamber in a polystyrene phantom. The phantom was irradiated with 9 MeV electron beams from Clinac 2100C with 6 x 6 cm electron cone. The relative dose at 6 mm depth where the lens is located was 4.2% with TLD and 5.1% with Markus chamber clinically when 2600 cGy are irradiated to the eyeball, the mapinary dose to the lens will be 109 cGy or 132 cGy, which will significantly reduce the cataract.

The Use of Lens Shielding Device(L.S.D.) for a Conjunctival Lymphoma

International Nuclear Information System (INIS)

Cho, Hyun Sang; Ju, Sang Gyu; Song, Ki Won; Park, Young Hwan

1997-01-01

When therapeutic irradiation is indicated for the orbital tumors, the greatest concern is the risk of radiation-induced cataract. Conjunctival lymphoma is one of the good examples. We would like to report the procedure of the lens shielding device(L.S.D) and the result of irradiated dose to the lens. L.S.D. consists of two parts : load alloy to attenuate electron beam, and dental acryl which completely covers the lead alloy to avoid discomfort of cornea from contacting directly with cerrobend and side scattering by cerrobend. And for easy location and removal, side bars were made on each side. Radiation doses were measured with TLD (TLD 3500 Hawshaw). Markus chamber in a polystyrene phantom. The phantom was irradiated with 9 MeV electron beams from Clinac 2100C with 6 x 6 cm electron cone. The relative dose at 6 mm depth where the lens is located was 4.2% with TLD and 5.1% with Markus chamber clinically when 2600 cGy are irradiated to the eyeball, the mapinary dose to the lens will be 109 cGy or 132 cGy, which will significantly reduce the cataract.

Kaliningradi biennaal / Sandra Jõgeva

Index Scriptorium Estoniae

Jõgeva, Sandra, 1976-

2008-01-01

IX rahvusvaheline graafikabiennaal "Kaliningrad-Königsberg 2008" Kaliningradi kunstigaleriis 15. IX-15. XI. Eesti väljapanek (kuraator Eha Komissarov, kujundaja Marko Nautras, osalejad: Jaanika Okk, Kaarel Kütas, Lauri Koppel, Gerda Märtens, Raul Meel, Lembe Ruben, HULA, Villem Jahu, Tiiu Pirsko, Mati Veermets, Sandra Jõgeva) sai ekspositsioonipreemia. Grand prix - Paulis Liepa, I preemia - Olrik Kohlhoff, II - Dominica Sadowska, III - Raffael Rheinsberg, eripreemia - Markus Lampinen

Eesti arhitektuur trügis maailmakaardile / Tiina Kolk

Index Scriptorium Estoniae

Kolk, Tiina

2004-01-01

Neli eesti arhitektide projekteeritud hoonet on pääsenud kunstikirjastuse Phaidon raamatusse "The Phaidon Atlas of Contemporary World Architecture": Indrek Allmanni paariselamu Luccas, Martin Aunini eramu Orro Tabasalus, Indrek Näki Neiseri tööstushoone ja büroo 3+1 arhitektide Villa V. 3+1 arhitektid Markus Kaasik, Andres Ojari, Ilmar Valdur ja Inga Raukas esindavad ka Leedumaad Eesti saatkonnahoonega Vilniuses. 4 ill

Essentializing the binary self: individualism and collectivism in cultural neuroscience

OpenAIRE

Martínez Mateo, M.; Cabanis, M.; Stenmanns, J.; Krach, S.

2013-01-01

Within the emerging field of Cultural Neurosciences (CN) one branch of research focuses on the neural underpinnings of "individualistic/Western" versus "collectivistic/Eastern" self-views. These studies uncritically adopt essentialist assumptions from classic cross-cultural research, mainly following the tradition of Markus & Kitayama (1991), into the domain of functional neuroimaging. In this comment we analyze recent publications and conference proceedings of the 18t...

A Comparison of Monte Carlo Tree Search and Rolling Horizon Optimization for Large Scale Dynamic Resource Allocation Problems

Science.gov (United States)

2015-05-01

decisions on the fly in an online retail environment. Tech. rep., Working Paper, Massachusetts Institute of Technology, Boston, MA. Arneson, Broderick , Ryan...Hayward, Philip Henderson. 2009. MoHex wins Hex tournament. International Computer Games Association Journal 32 114–116. Arneson, Broderick , Ryan B...Combina- torial Search. Enzenberger, Markus, Martin Muller, Broderick Arneson, Richard Segal. 2010. Fuego—an open-source framework for board games and

Metformin prevents the development of goiter in diabetes mellitus type 2

Directory of Open Access Journals (Sweden)

A K Lipatenkova

2013-06-01

Full Text Available Реферат по материалам статьи Ittermann T, Markus MR, Schipf S, Derwahl KM, Meisinger C, Volzke H. Metformin Inhibits Goitrogenous Effects of Type 2 Diabetes. Eur J Endocrinol. 2013 May 17;169(1:9-15. doi: 10.1530/EJE-13-0101. Print 2013.

Semiannual Report to the Congress. October 1, 2012 to March 31, 2013

Science.gov (United States)

2013-03-01

of a Taiwanese technology company, who attempted to purchase extra-high-per- formance microwave pyramid absorbers, ultra-broadband microwave...continental United States that did not previously have oversight by an Army financial management center. Army disbursing offices are located in Sinai, Egypt ...lucrative pay- ments for these companies. Markus opened or established control over multiple foreign bank accounts in Jordan and Egypt to receive

Die ideologíese funksie van niimte in die Markus-vertelling: 'n ...

African Journals Online (AJOL)

made that the 'way' (from Galilee to Jerusalem) must be seen as the ...... genoemde label is dit duidelik dat waar aan die een kant Galileo en Jerusalem onderskeidelik ...... Social-scientific criticism of the New Testament: More on methods and ...

Beyond the 'East-West' dichotomy:global variation in cultural models of selfhood

OpenAIRE

Vignoles, Vivian L.; Owe, Ellinor; Becker, Maja; Smith, Peter B.; Easterbrook, Matthew J.; González, Roberto; Didier, Nicolas; Carrasco, Diego; Schwartz, Seth J.; Des Rosiers, Sabrina E.; Villamar, Juan A.; Gavreliuc, Alin; Zinkeng, Martina; Kreuzbauer, Robert; Baguma, Peter

2016-01-01

Markus and Kitayama’s (1991) theory of independent and interdependent self-construals had a major influence on social, personality and developmental psychology by highlighting the role of culture in psychological processes. However, research has relied excessively on contrasts between North American and East Asian samples, and commonly-used self-report measures of independence and interdependence frequently fail to show predicted cultural differences. We revisited the conceptualization and me...

Žürii kommenteerib Kultuurkapitali arhitektuuripreemiaid 2008 / Marika Lõoke, Laila Põdra, Liina Jänes... [jt.

Index Scriptorium Estoniae

2009-01-01

Peapreemia: Markus Kaasik, Andres Ojari, Ilmar Valdur, Mihkel Tüür, Kalle Komissarov (Pärnu Keskraamatukogu hoone), tegevuspreemia: Maarja Kask, Ralf Lõoke, Neeme Külm, Ingrid Ruudi (projekt Gaasitoru 11. Veneetsia arhitektuuribiennaalil), aastapreemia: Maarja Kask, Ralf Lõoke, Karli Luik (Tartu Kesklinna Kooli juurdeehitus) ja Peep Jänes (Raudna Põhikooli spordihoone), sisearhitektuuri preemia: Tea Tammelaan, Malle Jürgenson, Krista Lepland, restaureerimispreemia: Mari Hammer, Tiiu Lõhmus, Helve Ilves, Villu Kadakas (Vanalinna Hariduskolleegiumi hoone)

False memory production :effects of self-consistent false information and motivated cognition

OpenAIRE

Brown, Martha

1996-01-01

Remembrance of one's personal past and the development of false memories have recently received intense public scrutiny. Based upon self-schema (Markus, 1977) and selfverification (Swann, 1987) theories, two studies were conducted to investigate the hypothesis that a self-schema guides cognitive processing of self-relevant information and thereby influences the construction of a memory that includes false information, particularly more so if this information is self-schema consistent than ...

Anterior cruciate ligament reconstruction using bone plug-free quadriceps tendon autograft: intermediate-term clinical outcome after 24–36 months

OpenAIRE

Schulz AP; Lange V; Gille J; Voigt C; Fröhlich S; Stuhr M; Jürgens C

2013-01-01

Arndt P Schulz,1 Vivien Lange,2 Justus Gille,1 Christine Voigt,3 Susanne Fröhlich,4 Markus Stuhr,1 Christian Jürgens5 1Department of Orthopedics, Trauma, and Sports Medicine, University Hospital Lübeck, Lübeck, Germany; 2Department of Rehabilitation, Sana Regio Klinikum, Wedel, Germany; 3Department of Sports Medicine and Arthroscopy, Diakoniekrankenhaus Friederikenstift, Hannover, Germany; 4Department of Orthopedics, University of Rostock, Rostock, Germany;...

Geneva University - Cancelled

CERN Multimedia

Université de Genève

2010-01-01

École de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENEVA 4 Tel: (022) 379 62 73 - Fax: (022) 379 69 92 Monday 19 April 2010 17h00 - Stückelberg Auditorium Into the darkness: Simulating the distribution of dark matter in our Universe Prof. Volker Springel - Heidelberg Institute for Theoretical Studies   THE COLLOQUIUM IS CANCELLED. Prof. Markus Büttiker

ZHAW Waedenswil: A new Approach in the Fight against Cancer.

Science.gov (United States)

Rimann, Markus

2018-03-30

A happy coincidence brought Dr Markus Rimann from ZHAW Waedenswil together with Dr Andreas Meyer from the start-up FGen and PD Dr Emanuela Felley-Bosco, Molecular Oncologist at Zurich University Hospital, to develop a technology platform for the manufacture and high throughput analysis of single mesothelioma spheroids. Armin Picenoni, former student in Chemistry for the Life Sciences at ZHAW, confirmed everything in writing his Master Thesis on this Innosuisse project.

Synergy in supramolecular chemistry

CERN Document Server

Nabeshima, Tatsuya

2014-01-01

Synergy and Cooperativity in Multi-metal Supramolecular Systems, T. NabeshimaHierarchically Assembled Titanium Helicates, Markus AlbrechtSupramolecular Hosts and Catalysts Formed by Self-assembly of Multinuclear Zinc Complexes in Aqueous Solution, Shin AokiSupramolecular Assemblies Based on Interionic Interactions, H. MaedaSupramolecular Synergy in the Formation and Function of Guanosine Quadruplexes, Jeffery T. DavisOn-Surface Chirality in Porous Self-Assembled Monolayers at Liquid-Solid Interface, Kazukuni Tahar

Kolmas aed = The Third Garden / Martin Melioranski

Index Scriptorium Estoniae

Melioranski, Martin

2006-01-01

Aed ja eramu Meriväljal Viimsi ja Väina tee nurgal. Projekt: Arhitektuuriagentuur. Autorid: Inga Raukas, Toomas Tammis, Tarmo Teedumäe. Haljastuse konsultant Signe Peipman. Projekt 2005, valmis 2006. Aed ja eramu Naeri tänaval. Projekt: Kolm Pluss Üks Arhitektid. Autorid: Markus Kaasik, Andres Ojari, Ilmar Valdur, Merje Müürsepp, Kalle Komissarov (2002). Projekt 2002-2004, valmis 2005. Ill.: kaks plaani, 6 värv. vaadet

Resonant Optical Gradient Force Interaction for Nano-Imaging and-Spectroscopy

Science.gov (United States)

2016-07-19

New J. Phys. 18 (2016) 053042 doi:10.1088/1367-2630/18/5/053042 PAPER Resonant optical gradient force interaction for nano-imaging and -spectroscopy...HonghuaUYang andMarkus BRaschke Department of Physics , Department of Chemistry, and JILA,University of Colorado, Boulder, CO80309,USA E-mail...honghua.yang@colorado.edu andmarkus.raschke@colorado.edu Keywords:nano spectroscopy, optical force, near-field optics Abstract The optical gradient force

Isomerization and dissociation in competition: the two-component dissociation rates of methyl acetate ions

Science.gov (United States)

Mazyar, Oleg A.; Mayer, Paul M.; Baer, Tomas

1997-11-01

Threshold photoelectron-photoion coincidence (TPEPICO) spectroscopy has been used to investigate the unimolecular chemistry of metastable methyl acetate ions, CH3COOCH3.+. The rate of molecular ion fragmentation with the loss of CH3O. and CH2OH radicals as a function of ion internal energy was obtained from the coincidence data and used in conjunction with Rice-Ramsperger-Kassel-Markus and ab initio molecular orbital calculations to model the dissociation/isomerization mechanism of the methyl acetate ion (A). The data were found to be consistent with the mechanism involving a hydrogen-bridged complex CH3CO[middle dot][middle dot][middle dot]H[middle dot][middle dot][middle dot]OCH2.+(E) as the direct precursor of the observed fragments CH3CO+ and CH2OH.. The two-component decay rates were modeled with a three-well-two-product potential energy surface including the distonic ion CH3C(OH)OCH2.+(B) and enol isomer CH2C(OH)OCH3.+(C), which are formed from the methyl acetate ion by two consecutive [1,4]-hydrogen shifts. The 0 K heats of formation of isomers B and C as well as transition states TSAB, TSBC, and TSBE (relative to isomer A) were calculated from Rice-Ramsperger-Kassel-Markus (RRKM) theory.

Psychiatric comorbidities in a young man with subacute myelopathy induced by abusive nitrous oxide consumption: a case report

OpenAIRE

Mancke, Falk; Kaklauskait?, Gintar?; Kollmer, Jennifer; Weiler, Markus

2016-01-01

Falk Mancke,1,2,* Gintare Kaklauskaite,1,* Jennifer Kollmer,3 Markus Weiler1 1Department of Neurology, 2Department of General Psychiatry, Center for Psychosocial Medicine, 3Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany *These authors contributed equally to this work Abstract: Nitrous oxide (N2O), a long-standing anesthetic, is known for its recreational use, and its consumption is on the rise. Several case studies have reported neurological and psychiatric ...

Figuur teeb võidukäiku / Krista Piirimäe

Index Scriptorium Estoniae

Piirimäe, Krista, 1946-

2006-01-01

Tartu kunstnike aastalõpunäitus Tartu Kunstimajas kuni 22. I. Näituse on kujundanud Maris Palgi ja Rauno Moss. Jaan Punga, Sven Saagi, Albert Gulki, Markus Kasemaa, Saskia Kasemaa, Rauno Mossi, Meiu Mündi, Külli Kalde, Anne Vasara, Piret Mihkelseni, Priit Pajose, Harri Puderselli, Imat Suumanni, Eda Lõhmuse, Sütevaka Andrese, Tiit Tamme, Helle Vahersalu, Malev Toome, Jass Kaselaane, Jaan Luige, Tõnis Paberiti ja Ahti Seppeti töödest

Mobile marketing and its implementations

OpenAIRE

Latto, Joel

2014-01-01

Latto, Joel Mobile marketing and its implementations Jyväskylä: University of Jyväskylä, 2014, 33 p. Information Systems Science, Bachelor’s Thesis Supervisor: Salo, Markus Mobile devices have become increasingly important marketing channel in recent years for all kinds of organizations. They allow marketers to bring forward relevant marketing information for the consumers based on location, purchase history, time and technology available. Although not brand new way of mar...

6th International Symposium on Molecular Allergology (ISMA)

OpenAIRE

Hilger, Christiane; Swiontek, Kyra; Fischer, J?rg; Hentges, Fran?ois; Lehners, Christiane; Morisset, Martine; Eberlein, Bernadette; Biedermann, Tilo; Ollert, Markus; Wildner, Sabrina; Stemeseder, Teresa; Freier, Regina; Briza, Peter; Lang, Roland; Batanero, Eva

2016-01-01

Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE-antibodies to alpha-Gal Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert O2 Structure...

Entrepreneuring mothers motivation and commitment from the perspective of possible selves

OpenAIRE

Vershinina, Natalia; Phillips, N.

2017-01-01

This paper has been accepted for ISBE conference in November 2017. We are hoping to only publish the abstract in proceedings as we are in the process of developing the manuscript for submission to a journal. Abstract Objectives We examine the relationships between how women cope with role conflict and develop self-conceptions during motherhood and whilst managing an entrepreneurial venture. Prior Work The concept of possible selves (Markus and Nurius, 1986), representing individuals’...

Three Jews in Günter Grass' novel The Tin Drum

Directory of Open Access Journals (Sweden)

Zobenica Nikolina N.

2017-01-01

Full Text Available In the novel The Tin Drum (Die Blechtrommel, 1959 Günter Grass depicts three periods of German history: pre-war time, World War II, and post-war time. In all the segments of the novel, there is a Jewish character: in the first part it is the toy dealer, Sigismund Markus; in the second, Mr Feingold; and in the third it is Ferdinand Schmuh. The aim of this paper is to determine similarities and differences among these characters, bearing in mind the changes in socio-political situation, as well as the status of Jews in the world of petite bourgeoisie. Sigismund Markus was in love with Oskar's mother, and he was loyal to her, even though she was cheating her husband with another man. He warned her of the changing circumstances and he himself decided to get baptised, in order to survive in the new society. However, he was attacked in Crystal Night then he killed himself in order to avoid the destiny which the Nazis have planned for him. The second Jew in the novel is a survivor, Mr Feingold. Although his entire family has been killed in the concentration camp Treblinka, he is eager to help and to protect Maria, Oskar and Kurt. He helps Oskar during the fever and eventually proposes to Maria, but Maria is now ready to leave Gdansk, so Mr Feingold was turned down, just like Markus few years back. Symbolically, the devoted love of the Jews for the Germans and for Gdansk has been refused, as well as hope for a fresh start for the Jews and Germans. While Markus and Feingold show love and respect for women and understanding for Oskar, Schmuh is embittered because Germans have not learnt to mourn and are incapable of crying. He is giving them an opportunity to learn it by serving them onions which makes them shed tears and open their hearts. However, this is only temporary; they do not really change; so Schmuh vents his negative feelings in cursing toilet women and regularly killing twelve sparrows in an afternoon. As he once exaggerated and killed one

Markus 16:1-8 in die konteks van 'n konstniksie van die Markaanse ...

African Journals Online (AJOL)

Gager notes that a sociological approach to early Christianity takes what redaction ...... die Markaanse ervaring die ander kant van die saak nie so 'getrou' weerspieel nie. Markaansc .... insider's knowledge of the apocalyptic code is bound to conclude that Mark and his ..... The ethics of Mark's gospel: In the middle of time.

Markus 16:1-8 in die konteks van 'n konstniksie van die Markaanse ...

African Journals Online (AJOL)

Time and place, intra-, inter-, and extra- community relations are in turn considered in theses. Expositions of pro and contra arguments for the theses emphasise the relativity of the proposed construction. In the second part of the article an attempt is made to understand Mark 16:1-8 in the imagined community context.

Impact of aerobic exercise on sleep and motor skills in children with autism spectrum disorders – a pilot study

OpenAIRE

Br; S; Jossen S; Holsboer-Trachsler E; Pühse U; Gerber M

2015-01-01

Serge Brand,1,2,* Stefanie Jossen,2,* Edith Holsboer-Trachsler,1 Uwe Pühse,2 Markus Gerber21Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders (ZASS), 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland*These authors contributed equally to this work and share the first authorshipBackground: Prevalence rates of autism spectrum disorder (ASD) have increased dramatically in the last two decad...

ERKÜ valimiste tulemused

Index Scriptorium Estoniae

2006-01-01

8. aprilli koosolekul kinnitas valimiste peakomitee XIX Esinduskogu liikmed: Mati Kõiva, Ylo Anson, Juhan Simonson, Airi Vaga, Gilda M. Karu, Taavo Virkhaus, Marju Rink-Abel, Markus Vaga, Eric Suuberg, Endel Reinpõld, Jaak Juhansoo, Ülle Ederma, Lya Karm, Heino Jõgis, Kersti Linask, Jaak Rakfeldt, Erik Puskar, Jüri Linask, Viiu Vanderer, Andres Kurrik, Mati Valdek Laan, Ilmar Vanderer, Henno Uus, Jüri Tults, Urmas Wompa, Astrid Jaanson, Jüri Virkus, Lilian G. G. Bein, Tiina Harris, Tõnu Vanderer

The book thief

Directory of Open Access Journals (Sweden)

Leandro Diniz

2008-04-01

Full Text Available The Book Thief (The Book Thief, in the original is an Australian writer of the novel juvenile Markus Zusak, published in 2006. In Brazil, his work was launched in March 2007 by the publisher Intrinsically, translated by Vera Ribeiro, and so far has sold nationally more than 105 thousand copies. Among the nine books that the author has published, only two books have translated into Portuguese: I am the messenger and The Book Thief.

Influences of International Attitudes and Possible Selves on Willingness to Communicate in English : A Comparative Analysis of Models for Japanese High School and University Learners of English

OpenAIRE

菅原, 健太; 佐野, 愛子; 河合, 靖; 横山, 吉樹; 中村, 香恵子; 三ッ木, 真実; Kenta, SUGAWARA; Aiko, SANO; Yasushi, KAWAI; Yoshiki, YOKOYAMA; Kaeko, NAKAMURA; Makoto, MITSUGI; Hokkaido University; Graduate School, Hokkaido University; Hokkaido University

2013-01-01

The importance of the willingness to communicate(WTC) in English has been emphasized in contemporary English education in Japan. Past research identified key elements of the WTC, but the relationships with individuals' future vision, which have been the focus of recent research on second language motivation, have not been explored in detail. Our study uses Markus and associates' theory of possible selves as a framework to capture the future-oriented self-cognition, and aims to investigate the...

Impact of aerobic exercise on sleep and motor skills in children with autism spectrum disorders – a pilot study

OpenAIRE

Brand, Serge; Jossen,Stefanie; Holsboer-Trachsler,Edith; Pühse,Uwe; Gerber,Markus

2015-01-01

Serge Brand,1,2,* Stefanie Jossen,2,* Edith Holsboer-Trachsler,1 Uwe Pühse,2 Markus Gerber21Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders (ZASS), 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland*These authors contributed equally to this work and share the first authorshipBackground: Prevalence rates of autism spectrum disorder (ASD) have increased dramatically in the last two d...

In the beginning was uranium

International Nuclear Information System (INIS)

Charles, D.

1992-01-01

This article traces the nuclear proliferation which followed Gernot Zippe's invention during the Second World War, of a gas centrifuge to extract Uranium 235 from Uranium. This rare isotope is at the core of nuclear reactors and of the atomic bomb. Despite attempts by the world's nuclear powers to prevent widespread availability of the centrifuge, it is today in use by emergent Third World countries to produce enriched uranium for weapons programmes. The gas centrifuge was developed in a Soviet camp by captured German scientists. Zippe later reconstructed his work from memory in the United States (U.S.) where it was published at the University of Virginia just before the U.S. government could impose a secrecy order. He adapted his work for the West German government to produce enriched uranium fuel for civilian power stations. This technology became the basis for the Urenco industrial consortium. The article concludes with speculation about the nuclear weapons programme in Iraq following the Gulf War, where their impressive arsenal of weapons equipment came from and how close Iraq is to producing its own bomb. (UK)

A lumped model of venting during thermal runaway in a cylindrical Lithium Cobalt Oxide lithium-ion cell

Science.gov (United States)

Coman, Paul T.; Rayman, Sean; White, Ralph E.

2016-03-01

This paper presents a mathematical model built for analyzing the intricate thermal behavior of a 18650 LCO (Lithium Cobalt Oxide) battery cell during thermal runaway when venting of the electrolyte and contents of the jelly roll (ejecta) is considered. The model consists of different ODEs (Ordinary Differential Equations) describing reaction rates and electrochemical reactions, as well as the isentropic flow equations for describing electrolyte venting. The results are validated against experimental findings from Golubkov et al. [1] [Andrey W. Golubkov, David Fuchs, Julian Wagner, Helmar Wiltsche, Christoph Stangl, Gisela Fauler, Gernot Voitice Alexander Thaler and Viktor Hacker, RSC Advances, 4:3633-3642, 2014] for two cases - with flow and without flow. The results show that if the isentropic flow equations are not included in the model, the thermal runaway is triggered prematurely at the point where venting should occur. This shows that the heat dissipation due to ejection of electrolyte and jelly roll contents has a significant contribution. When the flow equations are included, the model shows good agreement with the experiment and therefore proving the importance of including venting.

How to calibrate Grenz-beams in clinical practice?

Energy Technology Data Exchange (ETDEWEB)

Schaeken, B [Algemeen Ziekenhius Middelheim, Antwerp (Belgium); Bressers, E [Virga jesse Ziekenhius, Hasselt (Belgium)

1995-12-01

In recent years, considerable efforts have been spent improving the precision and consistency in the whole process of calibration of high energy photon and electron beams (national protocols, primary calibration facilities ....). The reading in air of 5 different ionisation chambers (NE2532, NE2536, NE2571, PTWM23342, Markus) in an X-ray beam (RT50, HVL=0.35 mm Al) has been compared. Ali NE chambers were provided with a calibration factor Nk, the PTW chamber was directly calibrated in dose water ND,W. The polarisation and recombination effects were measured. In our reference field (ssd=4cm, field diameter 40 mm), the readings in air for the dedicated plan parallel chambers deviated by not more than 8%. The measurements with the NE2571 chamber did not correspond very well with the other measurements. For the equipment in our hospital, the dose rate in air for the reference field was measured from 1971 on and found to be very stable: 17.36 Gy/min (0.48) (1sd). An attempt was made to measure the BSF for the field defining cones used in clinical practice using a Markus plane parallel chamber, but the resulting BSF did not correspond to those reported in BJR/suppl. 17. Special attention has been be paid to the calibration of beams with field size comparable to the dimension of the chamber window- chamber body.

Beyond the 'east-west' dichotomy: Global variation in cultural models of selfhood.

Science.gov (United States)

Vignoles, Vivian L; Owe, Ellinor; Becker, Maja; Smith, Peter B; Easterbrook, Matthew J; Brown, Rupert; González, Roberto; Didier, Nicolas; Carrasco, Diego; Cadena, Maria Paz; Lay, Siugmin; Schwartz, Seth J; Des Rosiers, Sabrina E; Villamar, Juan A; Gavreliuc, Alin; Zinkeng, Martina; Kreuzbauer, Robert; Baguma, Peter; Martin, Mariana; Tatarko, Alexander; Herman, Ginette; de Sauvage, Isabelle; Courtois, Marie; Garðarsdóttir, Ragna B; Harb, Charles; Schweiger Gallo, Inge; Prieto Gil, Paula; Lorente Clemares, Raquel; Campara, Gabriella; Nizharadze, George; Macapagal, Ma Elizabeth J; Jalal, Baland; Bourguignon, David; Zhang, Jianxin; Lv, Shaobo; Chybicka, Aneta; Yuki, Masaki; Zhang, Xiao; Espinosa, Agustín; Valk, Aune; Abuhamdeh, Sami; Amponsah, Benjamin; Özgen, Emre; Güner, E Ülkü; Yamakoğlu, Nil; Chobthamkit, Phatthanakit; Pyszczynski, Tom; Kesebir, Pelin; Vargas Trujillo, Elvia; Balanta, Paola; Cendales Ayala, Boris; Koller, Silvia H; Jaafar, Jas Laile; Gausel, Nicolay; Fischer, Ronald; Milfont, Taciano L; Kusdil, Ersin; Çağlar, Selinay; Aldhafri, Said; Ferreira, M Cristina; Mekonnen, Kassahun Habtamu; Wang, Qian; Fülöp, Márta; Torres, Ana; Camino, Leoncio; Lemos, Flávia Cristina Silveira; Fritsche, Immo; Möller, Bettina; Regalia, Camillo; Manzi, Claudia; Brambilla, Maria; Bond, Michael Harris

2016-08-01

Markus and Kitayama's (1991) theory of independent and interdependent self-construals had a major influence on social, personality, and developmental psychology by highlighting the role of culture in psychological processes. However, research has relied excessively on contrasts between North American and East Asian samples, and commonly used self-report measures of independence and interdependence frequently fail to show predicted cultural differences. We revisited the conceptualization and measurement of independent and interdependent self-construals in 2 large-scale multinational surveys, using improved methods for cross-cultural research. We developed (Study 1: N = 2924 students in 16 nations) and validated across cultures (Study 2: N = 7279 adults from 55 cultural groups in 33 nations) a new 7-dimensional model of self-reported ways of being independent or interdependent. Patterns of global variation support some of Markus and Kitayama's predictions, but a simple contrast between independence and interdependence does not adequately capture the diverse models of selfhood that prevail in different world regions. Cultural groups emphasize different ways of being both independent and interdependent, depending on individualism-collectivism, national socioeconomic development, and religious heritage. Our 7-dimensional model will allow future researchers to test more accurately the implications of cultural models of selfhood for psychological processes in diverse ecocultural contexts. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Book Review

Directory of Open Access Journals (Sweden)

Salvatore Filippone

2014-01-01

Full Text Available The book by Arjen Markus is a veritable tour de force among the possibilities opened up by the latest incarnation of Fortran, the longest-lived programming language on the planet and still one of the favourites by scientific programmers. It is not an introduction to the syntax and semantics of the latest language standard: it is more of a gourmet cookbook showing off a wide range of examples of what the new features allow a daring programmer to do.

Categorias Cluster

OpenAIRE

Queiroz, Dayane Andrade

2015-01-01

Neste trabalho apresentamos as categorias cluster, que foram introduzidas por Aslak Bakke Buan, Robert Marsh, Markus Reineke, Idun Reiten e Gordana Todorov, com o objetivo de categoriíicar as algebras cluster criadas em 2002 por Sergey Fomin e Andrei Zelevinsky. Os autores acima, em [4], mostraram que existe uma estreita relação entre algebras cluster e categorias cluster para quivers cujo grafo subjacente é um diagrama de Dynkin. Para isto desenvolveram uma teoria tilting na estrutura triang...

Virtual violin in the digital domain : physical modeling and model-based sound synthesis of violin and its interactive application in virtual environment

OpenAIRE

Holm, Jan-Markus

2004-01-01

Viulun mallintaminen on tunnustettu maailmanlaajuisesti erittäin haasteelliseksi ongelmaksi. Väitöskirjan syntymistä ja tutkimuksessa esitettyjen uusien tekniikoiden kehittämistä ovatkin ohjanneet pitkälle käytännön syyt. On ollut tarve pyrkiä luomaan aiempaa luotettavampia ja todenmukaisempia fysikaalisia malleja, mm. äänisynteesiä varten syntetisaattoreihin ja esimerkiksi mobiililaitteisiin, Jan-Markus Holm kertoo viulun fysikaalista mallintamista käsittelevän väitöstyönsä taustoista....

Multimedia over cognitive radio networks algorithms, protocols, and experiments

CERN Document Server

Hu, Fei

2014-01-01

PrefaceAbout the EditorsContributorsNetwork Architecture to Support Multimedia over CRNA Management Architecture for Multimedia Communication in Cognitive Radio NetworksAlexandru O. Popescu, Yong Yao, Markus Fiedler , and Adrian P. PopescuPaving a Wider Way for Multimedia over Cognitive Radios: An Overview of Wideband Spectrum Sensing AlgorithmsBashar I. Ahmad, Hongjian Sun, Cong Ling, and Arumugam NallanathanBargaining-Based Spectrum Sharing for Broadband Multimedia Services in Cognitive Radio NetworkYang Yan, Xiang Chen, Xiaofeng Zhong, Ming Zhao, and Jing WangPhysical Layer Mobility Challen

Services in wireless sensor networks modelling and optimisation for the efficient discovery of services

CERN Document Server

Becker, Markus

2014-01-01

In recent years, originally static and single purpose Wireless Sensor Networks have moved towards applications that need support for mobility and multiple purposes. These heterogeneous applications and services demand for a framework which distributes and discovers the various services, so that other pieces of equipment can use them. Markus Becker studies, extends, analytically models, simulates and employs the so called Trickle algorithm in measurements in a Wireless Sensor Network test bed for the service distribution. The obtained results apply to the application of the Trickle algorithm at

Uued agulimajad = New Suburb Houses / Andri Ksenofontov

Index Scriptorium Estoniae

Ksenofontov, Andri, 1962-

2005-01-01

Tallinna ajalooliste eeslinnade teke ja kujunemine. Agulite olukord tänapäeval ja haldus viimastel aastatel. Büroo 3+1 projekteeritud ühepereelamu Magasini kvartalis (arhitektid Andres Ojari, Markus Kaasik, Ilmar Valdur, Merje Müürisepp, Kalle Komissarov). Neljakorruseline elamu Õle t. 23/Härjapea t. 14, ühtlasi arhitektide Madis Eegi ja Margit Mutso kodu. Gert Sarve projekteeritud kahepereelamu Herne t. 9. KOKO arhitektide Raivo Kotovi ja Tõnis Kimmeli projekteeritud korterelamu Vabriku t. 33. Ill.: 12 plaani, 14 värv. vaadet

Handbook of graph drawing and visualization

CERN Document Server

Tamassia, Roberto

2013-01-01

Planarity Testing and Embedding Maurizio PatrignaniCrossings and Planarization Christoph Buchheim, Markus Chimani, Carsten Gutwenger, Michael Jünger, and Petra MutzelSymmetric Graph Drawing Peter Eades and Seok-Hee HongProximity Drawings Giuseppe LiottaTree Drawing Algorithms Adrian RusuPlanar Straight-Line Drawing Algorithms Luca VismaraPlanar Orthogonal and Polyline Drawing Algorithms Christian A. Duncan and Michael T. GoodrichSpine and Radial Drawings Emilio Di Giacomo, Walter Didimo, and Giuseppe LiottaCircular Drawing Algorithms Janet M. Six and Ioannis G. TollisRectangular Drawing Algori

A menina que roubava livros

OpenAIRE

Diniz, Leandro

2008-01-01

The Book Thief (The Book Thief, in the original) is an Australian writer of the novel juvenile Markus Zusak, published in 2006. In Brazil, his work was launched in March 2007 by the publisher Intrinsically, translated by Vera Ribeiro, and so far has sold nationally more than 105 thousand copies. Among the nine books that the author has published, only two books have translated into Portuguese: I am the messenger and The Book Thief. A Menina que Roubava Livros (The Book Thief, no original) ...

Jesus en geweld: Markus 12:1-12 (en par) en Thomas 65 | van Eck ...

African Journals Online (AJOL)

Jesus and violence: Mark 12:1-12 (and par) and. Thomas 65. As an advanced agrarian (aristocratic) society, first-century Palestine's social fabric was built on systemic tensions and conflicts between the elite (rulers) and the peasantry (the ruled). At the root of these conflicts were incompatible values (ideologies) and

Iraagi sõjas on USA sõduritele suurim oht keemia- ja biorelv / Markus Larsson

Index Scriptorium Estoniae

Larsson, Markus

2003-01-01

Kuveidis viibiv keemiarelva avastamise lahingüksus on valvel võimalikeks Iraagi ennetusrünnakuteks Kuwait City või riigis paiknevate USA sõjaväebaaside vastu. Skeem: Kaitseriietus keemiarelva vastu

Levitikus as agtergrond van Markus 5:25–34, geïnterpreteer in terme ...

African Journals Online (AJOL)

This article investigated whether Mark 5:25–34 proposes a radical discontinuity with the Jewish purity codes and subsequently, holds drastic liberating implications for women as far as access to the temple is concerned and more existentially speaking, access to Yahweh. It determined whether Leviticus speaks about ...

Levitikus as agtergrond van Markus 5:25–34, geïnterpreteer in terme ...

African Journals Online (AJOL)

2 Feb 2011 ... is nie onrein nie, want dit is normaal dat daar mis sal wees daar waar koeie beweeg; dit is dus in plek. Wanneer hierdie ... mis voor in die huis, 'n plek voor waar dit nie hoort nie en dan is dit onrein. Onreinheid verwys ..... die shalom kan ervaar wat haar so lank ontneem was. kai. i;sqi u`gih.j avpo. th/j ma ...

The deadly perception of the witness: focalization in Markus Zusak’s The Book Thief

OpenAIRE

Oliveira, Débora Almeida de; Maggio, Sandra Sirangelo

2017-01-01

http://dx.doi.org/10.5007/2175-8026.2017v70n1p135For a better understanding of a given narrative it is essential to be aware of the one who perceives (the focalizer). His beliefs and comprehension determine which characters and circumstances are to be ignored or closely examined through his use of sight, hearing, feeling, taste or smell. Therefore, the issue concerning focalization is relevant to be taken into consideration when a literary work is analyzed. In the present article the work by ...

The deadly perception of the witness: focalization in Markus Zusak’s The Book Thief

OpenAIRE

Débora Almeida de Oliveira; Sandra Sirangelo Maggio

2017-01-01

http://dx.doi.org/10.5007/2175-8026.2017v70n1p135 For a better understanding of a given narrative it is essential to be aware of the one who perceives (the focalizer). His beliefs and comprehension determine which characters and circumstances are to be ignored or closely examined through his use of sight, hearing, feeling, taste or smell. Therefore, the issue concerning focalization is relevant to be taken into consideration when a literary work is analyzed. In the present article the wor...

Proton beam dosimetry: a comparison between a plastic scintillator, ionization chamber and faraday cup

International Nuclear Information System (INIS)

Ghergherehchi, Mitra; Afarideh, Hossein; Mohammadzadeh, Ahmad; Boghrati, Behzad; Ghannadi, Mohammad; Aslani, Golam Reza

2010-01-01

In this study, a comparison was made between a plastic scintillator (BC400), a Faraday Cup (FC) and an ionization chamber (IC) used for routine proton dosimetry. Thin scintillators can be applied to proton dosimetry and consequently to proton therapy as relative dosimeters because of their water-equivalent nature, high energy-light conversion efficiency, low dimensions and good proportionality to the absorbed dose at low stopping powers. To employ such scintillators as relative dosimeters in proton therapy, the corrective factors must be applied to correct the quenching luminescence at the Bragg peak. A fine linear proportionality between the luminescence light yield Y and the proton flux in a thin (0.5 mm) scintillator for the 20 and 30 MeV proton beams were observed. The experimental peak/plateau ratios of Bragg Curve for 2, 1 and 0.5 mm scintillators with an accuracy of 0.5% were obtained to be 1.87, 1.91 and 2.30, respectively. With combination of the Markus chamber and the CR-39 detector, the peak/plateau ratio was improved to 3.26. The obtained data of the luminescence yield as a function of the specific energy loss is in agreement with the Craun-Birk's theory. Results show that the FC and Markus ionization chamber are in agreement within 4%, while the FC gives a lower dose evaluation. For a defined beam, the data for the fluence measurements are reproducible within a good accuracy. (author)

Stress-related neuropeptides and alcoholism: CRH, NPY and beyond

Science.gov (United States)

Ciccocioppo, Roberto; Gehlert, Donald R.; Ryabinin, Andrey; Kaur, Simranjit; Cippitelli, Andrea; Thorsell, Annika; Lê, Anh D.; Hipskind, Philip A.; Hamdouchi, Chafiq; Lu, Jianliang; Hembre, Erik J.; Cramer, Jeffrey; Song, Min; McKinzie, David; Morin, Michelle; Economidou, Daina; Stopponi, Serena; Cannella, Nazzareno; Braconi, Simone; Kallupi, Marsida; de Guglielmo, Giordano; Massi, Maurizio; George, David T.; Gilman, Jody; Hersh, Jacqueline; Tauscher, Johannes T.; Hunt, Stephen P.; Hommer, Daniel; Heilig, Markus

2009-01-01

This article summarizes the proceedings of a symposium held at the conference on “Alcoholism and Stress: A Framework for Future Treatment Strategies” in Volterra, Italy, May 6–9, 2008. Chaired by Markus Heilig and Roberto Ciccocioppo, this symposium offered a forum for the presentation of recent data linking neuropetidergic neurotransmission to the regulation of different alcohol related behaviours in animals and in humans. Dr. Donald Gehlert described the development of a new corticotrophin releasing factor (CRH) receptor 1 antagonist and showed its efficacy in reducing alcohol consumption and stress-induced relapse in different animal models of alcohol abuse. Dr. Andrey Ryabinin reviewed recent findings in his laboratory indicating a role of the urocortin 1 (Ucn) receptor system in the regulation of alcohol intake. Dr. Annika Thorsell showed data supporting the significance of the neuropetide Y (NPY) receptor system in the modulation of behaviours associated with a history of ethanol intoxication. Dr. Roberto Ciccocioppo focused his presentation on the nociceptin/orphanin FQ (N/OFQ) receptors as treatment targets for alcoholism. Finally, Dr. Markus Heilig showed recent preclinical and clinical evidence suggesting that neurokinin 1 (NK1) antagonism may represent a promising new treatment for alcoholism. Collectively, these investigators highlighted the significance of neuropeptidergic neurotransmission in the regulation of neurobiological mechanisms of alcohol addiction. Data also revealed the importance of these systems as treatment targets for the development of new medication for alcoholism. PMID:19913192

Spatial and temporal patterns of global H5N1 outbreaks

CSIR Research Space (South Africa)

Si, YL

2008-07-01

Full Text Available -96. Walter, C., Mcbratney, A. B., Rossel, R. A. V. and Markus, J. A., 2005. Spatial point-process statistics: concepts and application to the analysis of lead contamination in urban soil. Environmetrics, 16, pp. 339-355. Ward, M. P., Maftei, D., Apostu... OF GLOBAL H5N1 OUTBREAKS Y.L. Si a,c, *, P. Debba b, A. K. Skidmore a, A. G. Toxopeus a, L. Li c a ITC, Department of Natural Resources, 7500AA Enschede, The Netherlands – (yali, skidmore, toxopeus)@itc.nl b Council for Scientific and Industrial...

Proceedings of the 22nd ACM conference on Hypertext and hypermedia

DEFF Research Database (Denmark)

and Ubiquitous Hypermedia, chaired by Niels Olof Bouvin and Frank Shipman; Social Media (Linking People and Things), chaired by Andreas Hotho, Gerd Stumme and Markus Strohmaier; Interaction, Narrative, and Storytelling, chaired by Mark Bernstein and Frank Nack. Three keynote speakers represent the breadth, depth....... Noshir Contractor investigates factors that lead to the formation, maintenance and dissolution of dynamically linked social and knowledge networks. The Program Committee and the reviewers worked hard to select an excellent program from 104 paper submissions. We accepted 31 full papers and 4 short papers...

A new algorithm for finite element simulation of wedge osteotomies in voxel models with application to the tibia

Directory of Open Access Journals (Sweden)

Thomas Pressel

2010-01-01

Full Text Available Thomas Pressel1, Markus D Schofer1, Jörg Meiforth2, Markus Lengsfeld1, Jan Schmitt11Department of Orthopaedics and Rheumatology, University Hospital Marburg, Marburg, Germany; 2St. Vincentius Kliniken, Klinik für Orthopädie, Karlsruhe, GermanyAbstract: Wedge osteotomies are used to correct bone deformities or change the forces acting on bones and joints in the human body. Finite element models can be employed to simulate the effect of such operations on the bone or adjacent joints. The automatic generation of voxel models derived from computed tomography data is a common procedure, but the major drawback of the method lies in irregular model surfaces. Therefore, the concept of hybrid models combining voxel and tetrahedron meshes was developed. We present an algorithm to simulate wedge osteotomies in voxel models by adding tetrahedron to brick elements. Applicability of the procedure was tested by performing a parametric study using a tibia model created from computed tomography scans taken in vivo applying individually calculated force conditions. The osteotomy angle largely affected maximum stresses: at 2.5 degrees valgus, the stresses at the medial and lateral tibial plateau were equivalent, while increasing valgus angles reduced medial stresses. The algorithm described here is an improvement of former mesh generation procedures and allows a better representation of the geometry at the osteotomy level. The algorithm can be used for all wedge osteotomies and is not limited to the tibia.Keywords: finite element/osteotomy/voxel/pre-operative planning, simulation, mesh algorithm

[Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg] / Markus Pöhlmann

Index Scriptorium Estoniae

Pöhlmann, Markus

2003-01-01

Rets.: Vejas Gabriel Liulevicius. Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg. Aus dem Amerikanischen von Jürgen Bauer, Edith Nerke und Fee Engemann. Hamburg : 2002

Sognenavne, Aalborg Kommune (59 artikler). trap.dk

DEFF Research Database (Denmark)

Kællerød, Lars-Jakob Harding

2019-01-01

Artikler til Trap Danmarks netpublikation trap.dk Sognenavnene Ajstrup, Ansgars Sogn, Bislev, Budolfi, Dall, Ejdrup, Ellidshøj, Farstrup, Ferslev, Frejlev, Gistrup, Godthåb, Gudumholm, Gunderup, Gåser, Hals, Hammer, Hans Egedes Sogn, Hasseris, Horsens, Hou, Hvorup, Klarup, Komdrup, Lillevorde......, Lindholm, Lundby, Margrethe Sogn, Mou, Nibe, Nørholm, Nørre Kongerslev, Nørresundby, Nørre Tranders, Nøvling, Romdrup, Rørdal, Sankt Markus, Sebber, Sejlflod, Skalborg, Store Ajstrup, Storvorde, Sulsted, Svenstrup, Sønderholm, Sønder Kongerslev, Sønder Tranders, Ulsted, Vadum, Vejgaard, Vester Hassing......, Vesterkær, Vodskov, Vokslev, Volsted, Vor Frelsers Sogn, Vor Frue Sogn og Øster Hassing...

Energy and integrated dose dependence of MOSFET dosimeter for clinical electron beams

International Nuclear Information System (INIS)

Manigandan, D.; Bharanidharan, G.; Aruna, P.; Ganesan, S.; Tamil Kumar, T.; Rai

2008-01-01

In this study, the sensitivity (mV/cGy) and integral dose dependence of a MOSFET detector for different clinical electron beams was studied. Calibrated clinical electron beams (Varian 2100) were used for the exposure. A Markus type parallel plate chamber was used for the absolute dose measurements. In order to study the sensitivity of a MOSFET, the response of the ion chamber and MOSFET for the absorbed dose of 100 cGy was measured. The sensitivity of the MOSFET was then expressed as mV/cGy. Sensitivity was measured for 4-18 MeV electron beams. (author)

Sognenavne, Aarhus Kommune (57 artikler). trap.dk

DEFF Research Database (Denmark)

Kællerød, Lars-Jakob Harding

2019-01-01

, Mejlby, Møllevang, Mårslet, Mårslev, Ormslev, Ravnsbjerg, Risskov, Sabro, Sankt Johannes, Sankt Lukas, Sankt Markus, Sankt Paul, Skejby, Skelager, Skjoldhøj, Skæring, Skødstrup, Skåde, Spørring, Sønder Årslev, Tilst, Tiset, Todbjerg, Tranbjerg, Trige, Tulstrup, Vejlby, Viby, Vitved, Vor Frue Sogn, Ølsted......Artikler til Trap Danmarks netpublikation trap.dk Sognenavnene Astrup, Beder, Borum, Brabrand, Christians Sogn, Egå, Elev, Ellevang, Elsted, Framlev, Fredens Sogn, Fårup, Gellerup, Hasle, Harlev, Helligånds Sogn, Hjortshøj, Holme, Hvilsted, Kasted, Kolt, Langenæs, Lisbjerg, Lyngby, Lystrup, Malling...

The Ursern electricity utility - Positive and negative aspects

International Nuclear Information System (INIS)

Niederhaeusern, A.

2008-01-01

In this interview with Markus Russi, head of an electricity utility in the Swiss Alps, recent Swiss legislation such as the Energy law and the cost-covering remuneration of power from renewable energy sources is discussed. The production of the power generation facilities belonging to the utility - hydropower and wind energy - is discussed and future refurbishment and expansion work noted. The situation in the electricity market and co-operation with other local electricity utilities are also discussed and various disadvantages of the new Swiss electricity market legislation are noted. Future partnerships with other utilities with similar business strategies are discussed.

“The Garden of Arts”. Several Remarks on Zbigniew Rybczyński’s Orkiestra [The Orchestra

Directory of Open Access Journals (Sweden)

Iwona Grodź

2013-01-01

Full Text Available The garden presents itself as an area consciously created by the human being. Its representation is usually actualized in opposition both to what is natural and to what is artificial (e.g. to a city. Over many years now, the garden has been been considered to be a “cultural fossil”, and as such, an object of importance for literary critics, film critics, art historians, musicologists etc., and an anthropological phenomenon, which is demonstrated by contemporary juxtapositions of aesthetics with environmental science, pace Gernot Böhme, or the transcultural aesthetics promoted by Wolfgang Welsch. At this stage, we are very close to full understanding of the phenomenon of garden-topos, as well as the numerous garden metaphors. In Zbigniew Rybczyński’s film Orkiestra there are several areas of author’s interest in the garden created and filmed on a theatrical stage. The garden as a space of life-renewal, symbol of birth and metaphysical rebirth, a renewed experience of fulness. The garden as a space of ordered life, positive energy, areas of joy liberation, a synonym of goodness and ideals. Finally, as the symbol of return to creation, beauty, to the first beginning, to civilized and tame nature.

Music as atmosphere. Lines of becoming in congregational worship

Directory of Open Access Journals (Sweden)

Friedlind Riedel

2015-06-01

Full Text Available In this paper I offer critical attention to the notion of atmosphere in relation to music. By exploring the concept through the case study of the Closed Brethren worship services, I argue that atmosphere may provide analytical tools to explore the ineffable in ecclesial practices. Music, just as atmosphere, commonly occupies a realm of ineffability and undermines notions such as inside and outside, subject and object. For this reason I present music as a means of knowing the atmosphere. The first part of this paper points to the limits of an understanding of atmosphere as a constellation of things, as proposed by Gernot Böhme. In contrast to this, Hermann Schmitz conceptualises atmosphere as half-thing which suggests movement. Drawing on this, I propose to methodologically approach atmospheres as movements. Consequently, in the second part of this paper I closely analyse two motions as they cohere in Closed Brethren worship services: first, becoming (Deleuze and Guattari, a movement on the level of the individual worshiper; secondly, territorialisation (Deleuze and Guattari, a movement of the atmosphere towards its solidification. Here music as atmosphere is not a system of moral signification but a generative power affording intimate processes of divine encounter, whilst producing affective denominational difference.

From the nuclear stalemate to a nuclear-weapon free world. In memory of Klaus Fuchs

International Nuclear Information System (INIS)

Flach, Guenter; Fuchs-Kittowski, Klaus

2012-01-01

The following topics were dealt with: The first soviet atomic bomb and Klaus Fuchs, in illusory worlds of Andrei Sakharov, Edward Teller, and Klaus Fuchs, Klaus Fuchs as grandfather of the hydrogen bomb, memories of and thinking about Klaus Fuchs, the Scottish years of Klaus Fuchs 1937-1941, Klaus Fuchs in the mirror of the Venona documents, Gernot Zippe and the ultracentrifuge or east-west technology transfer in the cold war, secret impulses for the soviet nuclear project, responsibility of knowledge with anti-facism, philosophy, and science as well as peace as the first human right in the work of Klaus Fuchs, the request of Klaus Fuchs for a lasting peace, Klaus Fuchs in Daniel Granin's roman ''Escape to Russia'', ways to a nuclear-weapon free world, Otto Hahn and the declarations of Mainau and Goettingen, nuclear winter, initiatives of the GDR for the prohibition of weapons of mass destruction, nuclear weapons in negative entropy, militarism and antimilitarism of the nuclear age, contributions of the young Klaus Fuchs to statistical physics, nuclear disarmament and the peaceful use of nuclear energy, the responsibility of the scientists for a socially effective and efficient energy change, Berlin-Bucher contributions to a world free of biological weapons. (HSI)

From the nuclear stalemate to a nuclear-weapon free world. In memory of Klaus Fuchs; Vom atomaren Patt zu einer von Atomwaffen freien Welt. Zum Gedenken an Klaus Fuchs

Energy Technology Data Exchange (ETDEWEB)

Flach, Guenter; Fuchs-Kittowski, Klaus (eds.)

2012-07-01

The following topics were dealt with: The first soviet atomic bomb and Klaus Fuchs, in illusory worlds of Andrei Sakharov, Edward Teller, and Klaus Fuchs, Klaus Fuchs as grandfather of the hydrogen bomb, memories of and thinking about Klaus Fuchs, the Scottish years of Klaus Fuchs 1937-1941, Klaus Fuchs in the mirror of the Venona documents, Gernot Zippe and the ultracentrifuge or east-west technology transfer in the cold war, secret impulses for the soviet nuclear project, responsibility of knowledge with anti-facism, philosophy, and science as well as peace as the first human right in the work of Klaus Fuchs, the request of Klaus Fuchs for a lasting peace, Klaus Fuchs in Daniel Granin's roman ''Escape to Russia'', ways to a nuclear-weapon free world, Otto Hahn and the declarations of Mainau and Goettingen, nuclear winter, initiatives of the GDR for the prohibition of weapons of mass destruction, nuclear weapons in negative entropy, militarism and antimilitarism of the nuclear age, contributions of the young Klaus Fuchs to statistical physics, nuclear disarmament and the peaceful use of nuclear energy, the responsibility of the scientists for a socially effective and efficient energy change, Berlin-Bucher contributions to a world free of biological weapons. (HSI)

Sisearhitektide Liit premeeris / Triin Ojari

Index Scriptorium Estoniae

Ojari, Triin, 1974-

2004-01-01

ESL aastapreemiad 2003: parima ajaloolise interjööri ja parima kodu preemia - Leila Pärtelpoja ja Karl-Erik Tarbe kujundatud Villa Tannenrode Lükati teel Tallinnas, parim ühiskondlik interjöör - 3+1 arhitektide (Markus Kaasik, Andres Ojari, Ilmar Valdur, kaasautorid Ralf Lõoke, Kalle Komissarov; söögikoha tegi Taavi Aunre ja ühiskondliku mööbli Gert Sarv) kujundatud Mustamäe keskus, publitsistikapreemia - EKA sisearhitektuuri kateedri kataloog "Eesti Kunstiakadeemia sisearhitektuuri osakond 2002-2003". Ära märgiti kaks tooteseeriat: EGO garderoobid (EGO Mööbel OÜ) ning Jan J. Grapsi loodud "Incognito" mööblisari

"Der Schlüssel liegt in der Hand der Russen" / Toomas Hendrik Ilves ; interv. Markus Bernath

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2009-01-01

President Toomas Hendrik Ilves räägib NATO missioonist Afganistanis, NATO suhetest Venemaaga, Gruusia ja Ukraina liitumisest NATOga, Euroopa Liidu idasuunalisest partnerlusest ja kritiseerib Venemaa nõudmist luua Euroopas uus julgeolekuarhitektuur

Monte Carlo study of correction factors for the use of plastic phantoms in clinical electron dosimetry

International Nuclear Information System (INIS)

Araki, Fujio

2007-01-01

In some recent dosimetry protocols, plastic is allowed as a phantom material for the determination of an absorbed dose to water in electron beams, especially for low energy with beam qualities R 50 2 . In electron dosimetry with plastic, a depth-scaling factor, c pl , and a chamber-dependent fluence correction factor, h pl , are needed to convert the dose measured at a water-equivalent reference depth in plastic to a dose at a reference depth in water. The purpose of this study is to calculate correction factors for the use of plastic phantoms for clinical electron dosimetry using the EGSnrc Monte Carlo code system. RMI-457 and WE-211 were investigated as phantom materials. First the c pl values for plastic materials were calculated as a function of a half-value depth of maximum ionization, I 50 , in plastic. The c pl values for RMI-457 and WE-211 varied from 0.992 to 1.002 and from 0.971 to 0.979, respectively, in a range of nominal energies from 4 MeV to 18 MeV, and varied slightly as a function of I 50 in plastic. Since h pl values depend on the wall correction factor, P wall , of the chamber used, they are evaluated using a pure electron fluence correction factor, φ pl w , and P wall w and P wall pl for a combination of water or plastic phantoms and plane-parallel ionization chambers (NACP-02, Markus and Roos). The φ pl w and P wall (P wall w and P wall pl ) values were calculated as a function of the water-equivalent depth in plastic materials and at a reference depth as a function of R 50 in water, respectively. The φ pl w values varied from 1.024 at 4 MeV to 1.013 at 18 MeV for RMI-457, and from 1.025 to 1.016 for WE-211. P wall w values for plane-parallel chambers showed values in the order of 1.5% to 2% larger than unity at 4 MeV, consistent with earlier results. The P wall pl values of RMI-457 and WE-211 were close to unity for all the energy beams. Finally, calculated h pl values of RMI-457 ranged from 1.009 to 1.005, from 1.010 to 1.003 and from 1

Innovative automotive industry II. Trend-setting activities of young scientists in the industry and at universities; Innovative Automobiltechnik II. Zukunftsweisende Arbeiten von Nachwuchsforschern in der Industrie und an Universitaeten

Energy Technology Data Exchange (ETDEWEB)

Tschoeke, Helmut; Krahl, Juergen; Munack, Axel (eds.)

2011-07-01

Within the 2nd Science Symposium Automotive Engineering at 14th to 15th October, 2010 in Coburg (Federal Republic of Germany) the following lectures were held: (1) New fuel characteristics and ignition delay times with alternative fuels (Andreas Janssen); (2) Investigation of the interaction of engine oil with new fuels as well as the design of measures for lengthening the interval of oil change (Alexander Maeder); (3) Emissions from the combustion of vegetable oils and their esters and synthetic fuels in diesel engines under consideration of polycyclic aromatic hydrocarbons (Jens Schaak); (4) Optimization of the combustion of pure rapeseed oil in modern heavy-duty diesel engines (Markus Lueft); (5) Classification of accident scenarios by means of wavelet transformed and artificial neural networks (Bastian Fuhr); (6) A real-time parallel computer for the re-centralization of control units in automobiles (Stefan Aust); (7) Minimizing the gas formation in fuel pumps of spark ignition engines by means of re-cooling (Joerg Heyse); (8) Model-assisted management of air systems for a diesel engine of passenger cars by means of exhaust gas recirculation systems at low and high pressures (Markus Heuck); (9) Comparison of hybridization and two-step charging concepts enabling enhanced degrees of downsizing (Christian Wiegand); (10) Contaminant behaviour and load-bearing capacity of the 'Premixed Charge Compression Ignition' (Maximilian Brauer); (11) An approach for the metrological determination of the pressure boundary condition for the charge exchange calculation by means of the flow method (Jan Dreves); (12) Simulation of the charge exchange and combustion of a self-igniting spark ignition engines with direct injection (Lars Hartkopf); (13) Fundamental research on diesel injection nozzles with two rows of holes and self-penetrating injection jets (Christoph Menne); (14) Oscillating axial bearings in a diesel injection pump at boundary friction and fuel

SU-F-T-478: Effect of Deconvolution in Analysis of Mega Voltage Photon Beam Profiles

Energy Technology Data Exchange (ETDEWEB)

Muthukumaran, M [Apollo Speciality Hospitals, Chennai, Tamil Nadu (India); Manigandan, D [Fortis Cancer Institute, Mohali, Punjab (India); Murali, V; Chitra, S; Ganapathy, K [Apollo Speciality Hospital, Chennai, Tamil Nadu (India); Vikraman, S [JAYPEE HOSPITAL- RADIATION ONCOLOGY, Noida, UTTAR PRADESH (India)

2016-06-15

Purpose: To study and compare the penumbra of 6 MV and 15 MV photon beam profiles after deconvoluting different volume ionization chambers. Methods: 0.125cc Semi-Flex chamber, Markus Chamber and PTW Farmer chamber were used to measure the in-plane and cross-plane profiles at 5 cm depth for 6 MV and 15 MV photons. The profiles were measured for various field sizes starting from 2×2 cm till 30×30 cm. PTW TBA scan software was used for the measurements and the “deconvolution” functionality in the software was used to remove the volume averaging effect due to finite volume of the chamber along lateral and longitudinal directions for all the ionization chambers. The predicted true profile was compared and the change in penumbra before and after deconvolution was studied. Results: After deconvoluting the penumbra decreased by 1 mm for field sizes ranging from 2 × 2 cm till 20 x20 cm. This is observed for along both lateral and longitudinal directions. However for field sizes from 20 × 20 till 30 ×30 cm the difference in penumbra was around 1.2 till 1.8 mm. This was observed for both 6 MV and 15 MV photon beams. The penumbra was always lesser in the deconvoluted profiles for all the ionization chambers involved in the study. The variation in difference in penumbral values were in the order of 0.1 till 0.3 mm between the deconvoluted profile along lateral and longitudinal directions for all the chambers under study. Deconvolution of the profiles along longitudinal direction for Farmer chamber was not good and is not comparable with other deconvoluted profiles. Conclusion: The results of the deconvoluted profiles for 0.125cc and Markus chamber was comparable and the deconvolution functionality can be used to overcome the volume averaging effect.

Experimental determination of the effective point of measurement for various detectors used in photon and electron beam dosimetry.

Science.gov (United States)

Looe, Hui Khee; Harder, Dietrich; Poppe, Björn

2011-07-21

The subject of this study is the 'shift of the effective point of measurement', Δz, well known as a method of correction compensating for the 'displacement effect' in photon and electron beam dosimetry. Radiochromic EBT 1 films have been used to measure the 'true' TPR curves of 6 and 15 MV photons and 6 and 9 MeV electrons in the solid water-equivalent material RW3. For the Roos and Markus chambers, the cylindrical 'PinPoint', 'Semiflex' and 'Rigid-Stem' chambers, the 2D-Array and the E-type silicon diode (all from PTW-Freiburg), the positions of the effective points of measurement have been determined by direct or indirect comparison between their TPR curves and those of the EBT 1 film. Both for the Roos and Markus chambers, we found Δz = (0.4 ± 0.1) mm, which confirms earlier experimental and Monte Carlo results, but means a shortcoming of the 'water-equivalent window thickness' formula. For the cylindrical chambers, the ratio Δz/r was observed to increase with r, confirming a recent Monte Carlo prediction by Tessier (2010 E2-CN-182, Paper no 147, IDOS, Vienna) as well as the experimental observations by Johansson et al (1978 IAEA Symp. Proc. (Vienna) IAEA-SM-222/35 pp 243-70). According to a theoretical consideration, the shift of the effective point of measurement from the reference point of the detector is caused by a gradient of the fluence of the ionizing particles. As the experiments have shown, the value of Δz depends on the construction of the detector, but remains invariant under changes of radiation quality and depth. Other disturbances, which do not belong to the class of 'gradient effects', are not corrected by shifting the effective point of measurement.

Comparing calibration methods of electron beams using plane-parallel chambers with absorbed-dose to water based protocols

International Nuclear Information System (INIS)

Stewart, K.J.; Seuntjens, J.P.

2002-01-01

Recent absorbed-dose-based protocols allow for two methods of calibrating electron beams using plane-parallel chambers, one using the N D,w Co for a plane-parallel chamber, and the other relying on cross-calibration of the plane-parallel chamber in a high-energy electron beam against a cylindrical chamber which has an N D,w Co factor. The second method is recommended as it avoids problems associated with the P wall correction factors at 60 Co for plane-parallel chambers which are used in the determination of the beam quality conversion factors. In this article we investigate the consistency of these two methods for the PTW Roos, Scanditronics NACP02, and PTW Markus chambers. We processed our data using both the AAPM TG-51 and the IAEA TRS-398 protocols. Wall correction factors in 60 Co beams and absorbed-dose beam quality conversion factors for 20 MeV electrons were derived for these chambers by cross-calibration against a cylindrical ionization chamber. Systematic differences of up to 1.6% were found between our values of P wall and those from the Monte Carlo calculations underlying AAPM TG-51, and up to 0.6% when comparing with the IAEA TRS-398 protocol. The differences in P wall translate directly into differences in the beam quality conversion factors in the respective protocols. The relatively large spread in the experimental data of P wall , and consequently the absorbed-dose beam quality conversion factor, confirms the importance of the cross-calibration technique when using plane-parallel chambers for calibrating clinical electron beams. We confirmed that for well-guarded plane-parallel chambers, the fluence perturbation correction factor at d max is not significantly different from the value at d ref . For the PTW Markus chamber the variation in the latter factor is consistent with published fits relating it to average energy at depth

Characterization of a microDiamond detector in high-dose-per-pulse electron beams for intra operative radiation therapy.

Science.gov (United States)

Di Venanzio, C; Marinelli, Marco; Tonnetti, A; Verona-Rinati, G; Falco, M D; Pimpinella, M; Ciccotelli, A; De Stefano, S; Felici, G; Marangoni, F

2015-12-01

To characterize a synthetic diamond dosimeter (PTW Freiburg microDiamond 60019) in high dose-per-pulse electron beams produced by an Intra Operative Radiation Therapy (IORT) dedicated accelerator. The dosimetric properties of the microDiamond were assessed under 6, 8 and 9 MeV electron beams by a NOVAC11 mobile accelerator (Sordina IORT Technologies S.p.A.). The characterization was carried out with dose-per-pulse ranging from 26 to 105 mGy per pulse. The microDiamond performance was compared with an Advanced Markus ionization chamber and a PTW silicon diode E in terms of dose linearity, percentage depth dose (PDD) curves, beam profiles and output factors. A good linearity of the microDiamond response was verified in the dose range from 0.2 Gy to 28 Gy. A sensitivity of 1.29 nC/Gy was measured under IORT electron beams, resulting within 1% with respect to the one obtained in reference condition under (60)Co gamma irradiation. PDD measurements were found in agreement with the ones by the reference dosimeters, with differences in R50 values below 0.3 mm. Profile measurements evidenced a high spatial resolution of the microDiamond, slightly worse than the one of the silicon diode. The penumbra widths measured by the microDiamond resulted approximately 0.5 mm larger than the ones by the Silicon diode. Output factors measured by the microDiamond were found within 2% with those obtained by the Advanced Markus down to 3 cm diameter field sizes. The microDiamond dosimeter was demonstrated to be suitable for precise dosimetry in IORT applications under high dose-per-pulse conditions. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

SU-F-T-218: Validation of An In-Vivo Proton Range Verification Method for Reducing the Risk of Permanent Alopecia in the Treatment of Pediatric Medulloblastoma

Energy Technology Data Exchange (ETDEWEB)

Lucconi, G [Department of Medical Physics, S. Orsola-Malpighi University Hospital, Bologna (Italy); Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Bentefour, E; Janssens, G [Advanced Technology Group, Ion Beam Applications (IBA), Louvain la Neuve (Belgium); Deepak, S [Department of Physics, Central University of Karnataka, Karnataka 585367 (India); Weaver, K; Moteabbed, M; Lu, H-M [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States)

2016-06-15

Purpose: The clinical commissioning of a workflow for pre-treatment range verification/adjustment for the head treatment of pediatric medulloblastoma patients, including dose monitoring during treatment. Methods: An array of Si-diodes (DIODES Incorporated) is placed on the patient skin on the opposite side to the beam entrance. A “scout” SOBP beam, with a longer beam range to cover the diodes in its plateau, is delivered; the measured signal is analyzed and the extracted water equivalent path lengths (WEPL) are compared to the expected values, revealing if a range correction is needed. Diodes stay in place during treatment to measure dose. The workflow was tested in solid water and head phantoms and validated against independent WEPL measurements. Both measured WEPL and skin doses were compared to computed values from the TPS (XiO); a Markus chamber was used for reference dose measurements. Results: The WEPL accuracy of the method was verified by comparing it with the dose extinction method. It resulted, for both solid water and head phantom, in the sub-millimeter range, with a deviation less than 1% to the value extracted from the TPS. The accuracy of dose measurements in the fall-off part of the dose profile was validated against the Markus chamber. The entire range verification workflow was successfully tested for the mock-treatment of head phantom with the standard delivery of 90 cGy per field per fraction. The WEPL measurement revealed no need for range correction. The dose measurements agreed to better than 4% with the prescription dose. The robustness of the method and workflow, including detector array, hardware set and software functions, was successfully stress-tested with multiple repetitions. Conclusion: The performance of the in-vivo range verification system and related workflow meet the clinical requirements in terms of the needed WEPL accuracy for pretreatment range verification with acceptable dose to the patient.

Eesti Arhitektide Liidu aastapreemia 2015 = The annual prize of 2015 of the Union of Estonian Architects / Rainer Mahlamäki

Index Scriptorium Estoniae

Mahlamäki, Rainer

2015-01-01

Soome arhitekti Rainer Mahlamäki mõtteid Eesti kaasaegsest arhitektuurist, tema ringsõidust Tallinnasse, Kuressaarde, Pärnusse ja Tartusse. Eesti Arhitektide Liidu aastapreemia 2015 äramärkimine: villa Pärnus Lõuna 2a restaureerimine (arhitekt Jaak Huimerind, sisearhitekt Mari Kurismaa). Eesti Arhitektide Liidu aastapreemia 2015 kandidaadid: elu- ja ärihoone Tallinnas Kentmanni 6 (arhitekt Indrek Allmann); büroohoone Tallinnas Sõpruse pst 157 (arhitekt Indrek Suigusaar); Tallinna Tehnikaülikooli Kuressaare kolledži väikelaevaehituse kompetentsikeskuse katsebasseini ja laboratooriumite hoone Kuressaares Tallinna 19 (arhitektid Kalle Komissarov, Aet Ader, Mari Hunt, Kadri Klementi, Lembit-Kaur Stöör); White Beach golfi klubihoone Valgerannas Pärnumaal (arhitektid Jaan Port, Markus Nimik, Katrin Kaevats, Neeme Tiimus)

Mõned korrakaitseseadusega kaasnenud muudatused kriminaalmenetluses : järelevalve- ja süüteomenetluse piiritlemisprobleem / Markus Kärner

Index Scriptorium Estoniae

Kärner, Markus

2014-01-01

Isikusamasuse tuvastamine, vahetu sund ja valdaja tahte vastane sisenemine enne ja pärast 1. juulil 2014 jõustunud korrakaitseseadust. Riigikohtu praktikast. Artikkel põhineb osaliselt Tartu Ülikooli õigusteaduskonnas 2014. a kevadel kaitstud magistritööl "Isiku kinnipidamine süüteomenetluses ning selle piiritlemine teistest isiku- või liikumisvabadust piiravatest toimingutest"

Kuidas illegaalina USA-sse pääseda? Rio Grande ja Arizona tapvad kõrbed / Markus Larsson

Index Scriptorium Estoniae

Larsson, Markus

2004-01-01

Ameerika Ühendriikide ja Mehhiko raskesti kontrollitaval piiril peavad valvet vabatahtlikud ameeriklastest farmiomanikud ning immigratsiooni piiramist nõudvad kodanikud, kuid on ka neid vabatahtlikke, kelle eesmärk on aidata kõrbes hätta sattunud illegaale

„EU”: short for „ethical” union? The role of ethics in European Union law / Markus Frischhut

Index Scriptorium Estoniae

Frischhut, Markus

2015-01-01

Eetika ja moraali põhimõtetest ELi esmases ja teiseses õiguses ning institutsioonide tegevuses; Euroopa Kohtu praktikast ning Teaduse ja uute tehnoloogiate eetika Euroopa töörühma (EGE) hinnangutest

Essentializing the Binary Self: Individualism and Collectivism in Cultural Neuroscience

Directory of Open Access Journals (Sweden)

Marina eMartinez Mateo

2013-06-01

Full Text Available Within the emerging field of Cultural Neurosciences (CN one branch of research focuses on the neural underpinnings of "individualistic/Western" versus "collectivistic/Eastern" self-views. These studies uncritically adopt essentialist assumptions from classic cross-cultural research, mainly following the tradition of Markus & Kitayama (1991, into the domain of functional neuroimaging. In this comment we analyze recent publications and conference proceedings of the 18th Annual Meeting of the Organization for Human Brain Mapping (2012 and problematize the essentialist and simplistic understanding of "culture" in these studies. Further, we argue against the binary structure of the drawn "cultural" comparisons and their underlying Eurocentrism. Finally we scrutinize whether valuations within the constructed binarities bear the risk of constructing and reproducing a postcolonial, orientalist argumentation pattern.

Essentializing the binary self: individualism and collectivism in cultural neuroscience.

Science.gov (United States)

Martínez Mateo, M; Cabanis, M; Stenmanns, J; Krach, S

2013-01-01

Within the emerging field of cultural neuroscience (CN) one branch of research focuses on the neural underpinnings of "individualistic/Western" vs. "collectivistic/Eastern" self-views. These studies uncritically adopt essentialist assumptions from classic cross-cultural research, mainly following the tradition of Markus and Kitayama (1991), into the domain of functional neuroimaging. In this perspective article we analyze recent publications and conference proceedings of the 18th Annual Meeting of the Organization for Human Brain Mapping (2012) and problematize the essentialist and simplistic understanding of "culture" in these studies. Further, we argue against the binary structure of the drawn "cultural" comparisons and their underlying Eurocentrism. Finally we scrutinize whether valuations within the constructed binarities bear the risk of constructing and reproducing a postcolonial, orientalist argumentation pattern.

Implementation of Web-based Information Systems in Distributed Organizations

DEFF Research Database (Denmark)

Bødker, Keld; Pors, Jens Kaaber; Simonsen, Jesper

2004-01-01

This article presents results elicited from studies conducted in relation to implementing a web-based information system throughout a large distributed organization. We demonstrate the kind of expectations and conditions for change that management face in relation to open-ended, configurable......, and context specific web-based information systems like Lotus QuickPlace. Our synthesis from the empirical findings is related to two recent models, the improvisational change management model suggested by Orlikowski and Hofman (1997), and Gallivan's (2001) model for organizational adoption and assimilation....... In line with comparable approaches from the knowledge management area (Dixon 2000; Markus 2001), we relate to, refine, and operationalize the models from an overall organizational view by identifying and characterizing four different and general implementation contexts...

Levitikus as agtergrond van Markus 5:25–34, geïnterpreteer in terme van eer-en-skaamte

Directory of Open Access Journals (Sweden)

Elritia le Roux

2011-04-01

Full Text Available This article investigated whether Mark 5:25–34 proposes a radical discontinuity with the Jewish purity codes and subsequently, holds drastic liberating implications for women as far as access to the temple is concerned and more existentially speaking, access to Yahweh. It determined whether Leviticus speaks about women in such an androcentric and exclusive manner and whether Jewish culture is indeed so discriminating. This article argued that Mark 5:25–34 does indeed radically turn the Jewish purity codes upside down and that the Jesus movement proclaims a drastic liberation for women from social marginalisation. However, the original meaning of the text in Leviticus should not be viewed so negatively. The dreadful consequences of the exile and the destruction of the temple lead to the idea amongst the orthodox rabbi’s that the purity codes should be maintained in a very strict way. These codes were thought to ensure that the holiness of Yahweh would manifest in the social sphere, the people of Yahweh would be blessed and a catastrophe of these immense proportions would be avoided in future. Unfortunately, this lead to the degeneration of the cult, that became exclusive as many people were deprived from the presence of Yahweh. The author of the Gospel according to Mark is reacting to this and clearly voices his criticism against this marginalisation.

Ground source geothermal heat. Ground source heat pumps and underground thermal energy storage systems. Proceedings; Oberflaechennahe Geothermie. Erdgekoppelte Waermepumpen und unterirdische thermische Energiespeicher. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-01

At the ninth international user forum on shallow geothermal heat on 28th and 29th April, 2009, at BadStaffelstein (Federal Republic of Germany), the following lectures were held: (1) Information system on shallow geothermal heat for Bavaria (Marcellus Schulze); (2) Calculation of the spreading of temperature anomalies in groundwater as an instrument of planning of heat pump systems (Wolfgang Rauch); (3) Comparison of models for simulation of deep geothermal probes (Markus Proell); (4) Impact of the geometry of boreholes and probes on heat transport (Manfred Reuss); (5) Thermal respond tests and temperature depth profiles - Experience from research and practice (Markus Kuebert); (6) A model of simulation for the investigation of the impact of different heat transfer fluids on the efficiency of ground source heat pump devices (Roland Koenigsdorff); (7) The research project EWSplus - Investigations for quality assurance of geothermal probes (Mathieu Riegger); (8) Quality management of plants for the utilization of shallow geothermal heat with geothermal probes - the example of Baden-Wuerttemberg (Bruno Lorinser, Ingrid Stober); (9) Not every heat pump contributes to climate protection (Falk Auer); (10) Field measurements of heat pumps in residential buildings with modern standard and in older buildings (Marek Miara); (11) System technology for a great annual performance factor (Werner Schenk); (12) Modification of older geothermal heat probe devices for use with modern heat pumps (Klaus Friedrich Staerk); (13) Energy-efficient modernisation of a pensioners' condominium from the 1970s with solar-geothermal-air (Michael Guigas); (14) Evaluation and optimization of operation of seasonal storage systems in the foundations of office buildings (Herdis Kipry); (15) Evaluation of an innovative heating and cooling concept with rain water vessels, thermo-active building components and phase change materials in a residential building (Doreen Kalz); (16) Contracts for ground

Autoconceito dos professores: principais factores usando modelos de Análise de Dados Multivariada Teachers' self-concept: finding main factors and clusters by EDA models

Directory of Open Access Journals (Sweden)

Vitor Franco

2008-01-01

Full Text Available O autoconceito tem sido considerado uma dimensão muito importante da personalidade do professor, da sua prática e do seu desenvolvimento pessoal (MARKUS; WURF, 1987; SIMÕES, 2001. A investigação que apresentamos foi efectuada com 281 professores de Ciências da Natureza, do terceiro ciclo do Ensino Básico, em Portugal, usando o ICAC- Inventário Clínico do Auto Conceito (VAZ-SERRA, 1986. Na análise dos dados obtidos foram usados diferentes métodos de Análise Multivariada, apresentando-se os resultados da análise factorial de correspondências e nos modelos de classificação hierárquica baseados no coeficiente de afinidade. Os resultados obtidos: 1 confirmam a importância de dois grandes factores presentes no Autoconceito: aceitação social e auto-eficácia; 2 caracterizam estes principais factores no que se refere ao Autoconceito clínico dos professores; 3 mostram como esses factores são determinantes na forma como cada professor constroi o seu autoconceito.The self-concept has been considered as a very important dimension on teacher's personality, practice and development (MARKUS; WURF, 1987;SIMÕES, 2001. The present research concerns a sample of 281 teachers of Natural Science of the Third Cycle of Basic Education from Portugal that responded to the I.C.A.C. - Self-Concept Clinical Inventory (VAZ-SERRA, 1986. In the analysis of the questionnaires different multivariate data analysis methods have been used. This paper describes some results issued from correspondence analysis and hierarchical clustering models based on the affinity coefficient. The results obtained: 1 confirm the importance of two general main factors / types which are present in self-concept: social acceptance and self-efficiency; 2 characterise these main factors when teachers'clinical self-concept is concerned and 3 show how determinant these factors are for the building of self-concept that allow us to differentiate teachers.

SU-F-T-76: Total Skin Electron Therapy: An-End-To-End Examination of the Absolute Dosimetry with a Rando Phantom

Energy Technology Data Exchange (ETDEWEB)

Cui, G; Ha, J; Zhou, S; Cui, J; Shiu, A [University Southern California, Los Angeles, CA (United States)

2016-06-15

Purpose: To examine and validate the absolute dose for total skin electron therapy (TSET) through an end-to-end test with a Rando phantom using optically stimulated luminescent dosimeters (OSLDs) and EBT3 radiochromic films. Methods: A Varian Trilogy linear accelerator equipped with the special procedure 6 MeV HDTSe- was used to perform TSET irradiations using a modified Stanford 6-dual-field technique. The absolute dose was calibrated using a Markus ion chamber at a reference depth of 1.3cm at 100 cm SSD with a field size of 36 × 36 cm at the isocenter in solid water slabs. The absolute dose was cross validated by a farmer ion chamber. Then the dose rate in the unit of cGy/Mu was calibrated using the Markus chamber at the treatment position. OSLDs were used to independently verify the dose using the calibrated dose rate. Finally, a patient treatment plan (200 cGy/cycle) was delivered in the QA mode to a Rando phantom, which had 16 pairs of OSLDs and EBT3 films taped onto its surface at different anatomical positions. The doses recorded were read out to validate the absolute dosimetry for TSET. Results: The OSLD measurements were within 7% agreement with the planned dose except the shoulder areas, where the doses recorded were 23% lower on average than those of the planned. The EBT3 film measurements were within 10% agreement with the planned dose except the shoulder and the scalp vertex areas, where the respective doses recorded were 18% and 14% lower on average than those of the planned. The OSLDs gave more consistent dose measurements than those of the EBT3 films. Conclusion: The absolute dosimetry for TSET was validated by an end-to-end test with a Rando phantom using the OSLDs and EBT3 films. The beam calibration and monitor unit calculations were confirmed.

SU-E-T-665: Radiochromic Film Quenching Effect Reduction for Proton Beam Dosimetry

Energy Technology Data Exchange (ETDEWEB)

Aldelaijan, S; Alzorkany, F; Moftah, B; Alrumayan, F [King Faisal Specialist Hospital & Research Centre, Riyadh (Saudi Arabia); Seuntjens, J [McGill University, Montreal, QC (Canada); Lewis, D [RCF Consulting, LLC, Monroe, CT (United States); Devic, S [McGill University, Montreal, QC (Canada); Jewish General Hospital, Montreal, QC (Canada)

2015-06-15

Purpose: Depending on the useful dose range in which radiochromic films operate, number of different radiochromic film models have been designed. The impact of different film models on quenching effect for percent depth dose (PDD) measurements in proton beams has been investigated. Methods: Calibrated PTW Markus ionization chamber was used to measure PDD and beam output for 26.5 MeV protons produced by CS30 cyclotron. An aluminum cylinder was added in front of the beam exit serving as a radiation shutter. The measured signal was normalized to a monitor chamber reading and subsequently scaled by ratio of water-to-air stopping powers at given depth, while the effective depth of measurements was scaled by ratios of material-to-water physical densities and CSDA ranges. Output was measured in water at 2.1 mm reference-depth in the plateau upstream from the Bragg peak. Following the TRS-398 reference dosimetry protocol for proton beams, the output was calibrated in water. Three radiochromic film models (EBT, EBT3 and HD-V2) were calibrated within Lexan phantom positioned at the same water-equivalent depth. Thicknesses of films sensitive layers were 34 µm, 30 µm and 8 µm, respectively. Small film pieces (1 x 2 cm{sup 2}) were positioned within polyethylene phantom along the beam central axis with an angulation of 5° for PDD measurements. Results: While the output of the proton beam was found to be around 7 Gy/sec, the actual value of the output per monitor chamber reading (2.32 Gy/nC) was used for reference-dose irradiations during film calibration. Dose ratios at the Bragg peak relative to the reference-depth were 3.88, 2.52, 2.19, and 2.02 for the Markus chamber, HD-V2, EBT3, and EBT film models, respectively. Conclusion: Results at hand suggest that quenching effect is reduced when a radiochromic film model with smaller sensitive layer thickness is used for PDD measurements in proton beams. David Lewis is the owner of RCF Consulting, LLC.

State-of-the-Art: Research Theoretical Framework of Information Systems Implementation Research in the Health Sector in Sub-Saharan Africa

DEFF Research Database (Denmark)

Tetteh, Godwin Kofi

2014-01-01

This study is about the state-of-the-art of reference theories and theoretical framework of information systems implementation research in the health industry in the Sub-Saharan countries from a process perspective. A process – variance framework, Poole et al, (2000), Markus & Robey, (1988......) and Shaw & Jarvenpaa, (1997) is employed to examine reference theories employed in research conducted on information systems implementation in the health sector in the Sub-Saharan region and published between 2003 and 2013. Using a number of key words and searching on a number of databases, EBSCO, CSA...... the process theoretical framework to enhance our insight into successful information systems implementation in the region. It is our optimism that the process based theoretical framework will be useful for, information system practitioners and organisational managers and researchers in the health sector...

Culture and Negotiator Cognition: Judgment Accuracy and Negotiation Processes in Individualistic and Collectivistic Cultures.

Science.gov (United States)

Gelfand; Christakopoulou

1999-09-01

In this paper, we argue that judgment biases in negotiation are perpetuated by underlying cultural values and ideals, and therefore, certain judgment biases will be more prevalent in certain cultural contexts. Based on theory in cultural psychology (Markus & Kitayama, 1991; Triandis, 1989), we considered the notion that fixed pie error, a judgment bias in which negotiators fail to accurately understand their counterparts' interests (Pruitt & Lewis, 1975; Thompson & Hastie, 1990), would be more prevalent at the end of negotiations in the United States, an individualistic culture, than Greece, a collectivistic culture. The results of a 2-week computer-mediated intercultural negotiation experiment, which took place between American students in Illinois and Greek students in Athens, supported this view. Theoretical implications of culture and cognition in negotiation are also discussed. Copyright 1999 Academic Press.

Essentializing the binary self: individualism and collectivism in cultural neuroscience

Science.gov (United States)

Martínez Mateo, M.; Cabanis, M.; Stenmanns, J.; Krach, S.

2013-01-01

Within the emerging field of cultural neuroscience (CN) one branch of research focuses on the neural underpinnings of “individualistic/Western” vs. “collectivistic/Eastern” self-views. These studies uncritically adopt essentialist assumptions from classic cross-cultural research, mainly following the tradition of Markus and Kitayama (1991), into the domain of functional neuroimaging. In this perspective article we analyze recent publications and conference proceedings of the 18th Annual Meeting of the Organization for Human Brain Mapping (2012) and problematize the essentialist and simplistic understanding of “culture” in these studies. Further, we argue against the binary structure of the drawn “cultural” comparisons and their underlying Eurocentrism. Finally we scrutinize whether valuations within the constructed binarities bear the risk of constructing and reproducing a postcolonial, orientalist argumentation pattern. PMID:23801954

Ergonomic project of the work and innovation in the virtual-actual dynamic: a theoretical-conceptual contribution

Directory of Open Access Journals (Sweden)

Gilbert Cardoso Bouyer

2015-12-01

Full Text Available The main purpose of this paper is to amplify the current theoretical scenario of “Ergonomics of Project” area, according to the knowledge creation/innovation theory, and his concepts of virtual and subjectivity in the Work. This theoretical-conceptual article aims to shed new light on the relations between innovation and present-day efforts toward a scientific theory of knowledge in the Work, with its complex structure of theories, hypotheses and disciplines. There is in this paper a new approach to understand  the Contemporary Ergonomic Project in a kind of Socio-Epistemological Engineering initiated by Markus F. Peschl in the University of Vienna. The methods employed were the systematic review and adaptation of Socio-Epistemological Engineering’s concepts in the actual context of epistemological and ontological principles of Ergonomics of Project.

Wind power - An impulse or just frustration for business?

International Nuclear Information System (INIS)

Wellstein, J.

2005-01-01

This article deals with the question raised as to whether the development of wind power can provide an impulse for industry. The answers provided by Markus Geissmann from the Swiss Federal Office of Energy (SFOE) and Robert Horbaty, head of 'Suisse Eole' - a Swiss society that supports the use of wind energy - are presented in the form of an interview. In particular, the fact that certain Swiss manufacturers have established themselves in the international wind energy market is discussed - in spite of the relatively low proportion of wind energy actually generated in Switzerland. The various factors influencing both on-shore and off-shore wind-power installations are discussed. The products and services offered are discussed and also the up-and-coming market for the replacement of older wind-power installations is looked at

Comparison between AAPM TG-51 and IAEA TRS-398 for plane parallel ionization chambers irradiated by clinical electron beams

International Nuclear Information System (INIS)

Mahmoud, M.A.

2005-01-01

We compared the results of absorbed dose determined at reference conditions according to AAPM T G-51 and IAEA TRS-398 using plane parallel ionization chambers. The study showed agreement between the two protocols for Holt ,Exradin P11, NACP, Attix RMI 449 and Roos ionization chambers. For Markus ionization chambers the absorbed dose calculated using AAPM TG-51 is higher than that calculated using IAEA TRS-398 by 1.8 % for R 5 0 =2 cm and decrease with increased R 5 0 to reach 1.2 % for R 5 0 =20 cm. For Capintec PS-033 ionization chambers the absorbed dose calculated using AAPM TG-51 is constantly higher than that calculated by IAEA TRS-398 by 1.5 %. A theoretical explanation was introduced for these results

Biogas plants; Biogasanlagen

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

Within the KRdL expert meeting at 30th October, 2012 in Bonn (Federal Republic of Germany), the following lectures were held: (1) New requirements on biomass conversion plants based on the Federal Nuisance Control Ordinance (Hans-Peter Ewens); (2) State of the art of the operation of biomass conversion plants (Christina Dornack); (3) Implementation of the regulation VDI 3475 sheet 4 (Markus Helm); (4) Handling of constraints of residents in the licensing procedure as well as during operation (Helmar Hentschke); (5) Explosion protection for biomass conversion plants considering the matters of immission control (Michael Faber); (6) Microbiological and epidemic-hygienic aspects of agricultural biomass conversion plants and their fermentation residues (Werner Philipp); (7) Emissions of climatic relevant gases at the biogas production (Jacqueline Daniel-Gromke); (8) State of the art in the biogas processing (Joachim Krassowski).

Monte Carlo Simulation of Electron Beams for Radiotherapy - EGS4, MCNP4b and GEANT3 Intercomparison

CERN Document Server

Trindade, A; Alves, C M; Chaves, A; Lopes, C; Oliveira, C; Peralta, L

2000-01-01

In medical radiation physics, an increasing number of Monte Carlo codes are being used, which requires intercomparison between them to evaluated the accuracy of the simulated results against benchmark experiments. The Monte Carlo code EGS4, commonly used to simulate electron beams from medical linear accelerators, was compared with GEANT3 and MCNP4b. Intercomparison of electron energy spectra, angular and spatial distribution were carried out for the Siemens KD2 linear accelerator, at beam energies of 10 and 15 MeV for a field size of 10x10 cm2. Indirect validation was performed against electron depth doses curves and beam profiles measured in a MP3-PTW water phantom using a Markus planar chamber. Monte Carlo isodose lines were reconstructed and compared to those from commercial treatment planning systems (TPS's) and with experimental data.

Highly Accurate and Precise Infrared Transition Frequencies of the H_3^+ Cation

Science.gov (United States)

Perry, Adam J.; Markus, Charles R.; Hodges, James N.; Kocheril, G. Stephen; McCall, Benjamin J.

2016-06-01

Calculation of ab initio potential energy surfaces for molecules to high accuracy is only manageable for a handful of molecular systems. Among them is the simplest polyatomic molecule, the H_3^+ cation. In order to achieve a high degree of accuracy (Diniz, J.R. Mohallem, A. Alijah, M. Pavanello, L. Adamowicz, O.L. Polyansky, J. Tennyson Phys. Rev. A (2013), 88, 032506 O.L. Polyansky, A. Alijah, N.F. Zobov, I.I. Mizus, R.I. Ovsyannikov, J. Tennyson, L. Lodi, T. Szidarovszky, A.G. Császár Phil. Trans. R. Soc. A (2012), 370, 5014 J.N. Hodges, A.J. Perry, P.A. Jenkins II, B.M. Siller, B.J. McCall J. Chem. Phys. (2013), 139, 164201 A.J. Perry, J.N. Hodges, C.R. Markus, G.S. Kocheril, B.J. McCall J. Molec. Spectrosc. (2015), 317, 71-73.

Procedure for obtaining visas for Switzerland and France - Signature rights

CERN Multimedia

2013-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories.  Where relevant, detailed procedures for obtaining visas apply.   Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Patrick FASSNACHT (PH-ADO) David FOSTER (IT – DI) Nathalie GRÜB (PH – AGS) Tadeusz KURTYKA (DG – PRJ) Markus NORDBERG (PH – ADO) Cécile NOELS (DG – PRJ) Maria QUINTAS (HR – SPS) Kate RICHARDSON (PH-AGS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla TIHINEN (PH – AGS) Emmanuel...

Procedure for obtaining visas for Switzerland and France Signature rights

CERN Multimedia

DG Unit

2012-01-01

In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories.  Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (PH – CMO) Oliver BRÜNING (BE – ABP) Michelle CONNOR (PH – AGS) Patrick FASSNACHT (PH-ADO) David FOSTER (IT – DI) Nathalie GRÜB (PH – AGS) Tjitske KEHRER (DG-DI) Tadeusz KURTYKA (DG – PRJ) Markus NORDBERG (PH – ADO) Cécile NOELS (DG – PRJ) Maria QUINTAS (HR – SPS) Kate RICHARDSON (PH-AGS) Jeanne ROSTANT (PH – AGS) José SALICIO-DIEZ (PH – AGS) Ulla TIHINEN (PH – AG...

ETH Zurich tour at CERN.

CERN Multimedia

Maximilien Brice

2002-01-01

Right to left: Thomas Wobmann and Markus Zemp visit the LHC tunnel at CERN with G nther Dissertori and Marcel Wyler of ETH Zurich. Their visit was part of the top prize for a competition organised by the ETH department of physics to coincide with its open day in June. Residents of Zurich and surrounding Swiss cantons were invited to answer five physics questions broadcast on local radio and the Internet the week before the open day. The two winners' reward for knowing who did not believe that God plays dice, among other things, was a flight offered by Swiss International Air Lines to Geneva and a VIP tour of CERN. One highlight was a trip to the underground site of the future CMS experiment, where the scale of the enormous cavern makes construction machines look like children's toys.

Transforming business models through big data in the textile industry

DEFF Research Database (Denmark)

Aagaard, Annabeth

, such as textile, and have led to disruption of established business models (Westerman et al., 2014; Weill and Woerner, 2015). Yet, little is known of the managerial process and facilitation of the digital transformation of business models through big data (McAfee and Brynjolfsson, 2012; Markus and Loebbecke, 2013).......The extensive stream of work on business models (BM) and business model innovation (BMI) has generated many important insights (Amit & Zott, 2001; Osterwalder, 2004; Markides, 2008, 2013; Chesbrough 2010; Teece, 2010; Zott et al, 2011). Yet, our understanding of business models remains fragmented...... as stressed by Zott et al. (2011), Weill et al. (2011) and David J. Teece (2010: 174), who states that: “the concept of a business model lacks theoretical grounding in economics or in business studies”. With the acceleration of digitization and use of big data analytics quality data are accessible...

The nuclear phase-out and its consequences; Der Atomausstieg und seine Folgen

Energy Technology Data Exchange (ETDEWEB)

Ludwigs, Markus

2016-07-01

As a lesson from the Fukushima nuclear disaster, a radical change has taken place in climate and energy policy in Germany since 2011. This is characterized by the phase-out of the nuclear energy, which is fixed by the 13th Atomic Enforcement Act, by the end of 2022. This entails a multitude of complex legal questions and subsequent problems. The latest decisions are the forthcoming decisions of the BVerfG on the constitutional consistency of the nuclear phase-out law and nuclear fuel tax, Vattenfall's much discussed arbitration award before the ICSID arbitration court, and controversial legal questions both in the context of the decommissioning and dismantling of nuclear power plants and the disposal of highly radioactive waste. In addition, the moral-ethical evaluation of the nuclear phase-out and the power turn-around is the focus of the interdisciplinary approach. The problem clusters are analyzed by the contributions of the anthology. He documents a conference organized by Professor Dr. Markus Ludwig, which took place on April 8, 2016, at the University of Wuerzburg, within the framework of a project funded by the Fritz Thyssen Stiftung (''The Law of the Energy Transition''). [German] Als Lehre aus der Atomkatastrophe von Fukushima ist in Deutschland seit 2011 ein radikaler Wandel in der Klima- und Energiepolitik erfolgt. Praegend hierfuer ist der durch die 13. Atomgesetznovelle fixierte Ausstieg aus der Kernenergie bis Ende 2022. Damit verbunden ist eine Vielzahl komplexer Rechtsfragen und Folgeprobleme. Aktuelle Schlaglichter bilden die anstehenden Entscheidungen des BVerfG zur Verfassungskonformitaet von Atomausstiegsgesetz und Kernbrennstoffsteuer, die vieldiskutierte Schiedsklage von Vattenfall vor dem ICSID-Schiedsgericht sowie die kontroversen Rechtsfragen sowohl im Kontext der Stilllegung und des Rueckbaus von Kernkraftwerken als auch hinsichtlich der Endlagerung hochradioaktiver Abfaelle. Daneben steht in interdisziplinaerer

Surface-near geothermal energy. Ground coupled heat pumps and underground thermal energy storage; Oberflaechennahe Geothermie. Erdgekoppelte Waermepumpen und unterirdische thermische Energiespeicher

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-01

Within the eleventh International User Forum at 27th/28th September, 2011 in Regensburg (Federal Republic of Germany) the following lectures were held: (1) Ecologic evaluation of heat pumps - a question of approach (Roland Koenigsdorff); (2) An actual general comment to WHG, the preparations for the new VAUwS and possible consequences on the surface-near geothermal energy (Walker-Hertkorn); (3) Field-test experiences: Ground source heat pumps in small residential buildings (Jeannette Wapler); (4) GeoT*SOL basic - Program for the evaluation and simulation of heat pump systems (Bernhard Gatzka); (5) Monitoring and modelling of geothermal heat exchanger systems (Fabian Ochs); (6) Thermal response tests for the quality assurance of geothermal heat probes (Markus Proell); (7) Process of determining an untroubled soil temperature in comparison (Andreas Koehler); (8) Borehole resistance - Is the TRT measured value also the planning value? (Roland Koenigsdorff); (9) Consideration of the heat transport in geothermal probes (Martin Konrad); (10) Process of evaluation the sealing of geothermal probes with backfilling materials (Manfred Reuss); (11) Quality assessment of geothermal probes in real standard (Mathieu Riegger); (12) Comparison of flat collectors salt water and direct evaporation, design, impacs, consequences (Bernhard Wenzel); (13) Non-covered photovoltaic thermal collectors in heat pump systems (Erik Bertram); (14) Seasonal geothermal probe-heat storage - Heat supply concepts for objects with overbalancing heating level of more than 100 kW (Volker Liebel); (15) Application of geothermal probe fields as a cold storage (Rolf Wagner); (16) Geothermal energy and waste water warmth: State of the art and new technologies for a combined utilization (Wolfram Stodtmeister); (17) Integration of a heat pump into a solar supported local heat supply in Neckarsulm (Janet Nussbicker-Lux); (18) Regenerative heating with photovoltaics and geothermal energy (Christoph Rosinski

LET dependence of GafChromic films and an ion chamber in low-energy proton dosimetry

International Nuclear Information System (INIS)

Kirby, Daniel; Parker, David; Green, Stuart; Hugtenburg, Richard; Wojnecki, Cecile; Palmans, Hugo

2010-01-01

Dosimetry using a PMMA phantom was performed in 15 and 29 MeV proton beams from the Birmingham cyclotron, with a Markus parallel-plate ionization chamber and GafChromic EBT and MD-V2-55 film. Simulations of the depth-dose curves were performed with FLUKA 2008.3 and MCNPX 2.5.0, which agreed almost perfectly with each other in range and only differed by 2% in the Bragg peak (BP) region. FLUKA was also used to calculate k Q factors for Markus chamber measurements as an improvement to the IAEA TRS-398 values in low-energy beams. FLUKA depth-dose simulations overestimate the BP height measured by ion chamber by about 10%, where the initial proton energy spread was estimated by fitting to the slope of the measured BP distal edge. Both GafChromic films showed an under-response in the BP compared to ion chamber; however, EBT exhibits this effect at lower energies than MD-V2-55. A possible reason for this is attributed to the shape and arrangement of the monomer particles being different in the active components of EBT and MD-V2-55. Relative effectiveness (RE) of both films is presented as functions of residual range R res in water and peak proton energy determined by FLUKA, with considerations for the spatial separation of the two active layers in each film. The proton energies at which RE reduces to 90% of maximum film response are 6.7 and 3.2 MeV for MD-V2-55 and EBT, respectively. Additionally, a beam quality correction factor (g Q,Q 0 ) is suggested for both GafChromic films, involving water-to-film stopping power ratios evaluated using ICRU recommendations, and a polymer yield factor G Q 0 /G Q . RE in this work is equated to the reciprocal of the polymer yield factor. The calculated values of (s w,film ) Q /(s w,film ) Q 0 are constant within 2.1% and 1.2% across the proton energy range of 1-300 MeV for EBT and MD-V2-55, respectively, so it is concluded that the polymer yield factor is the dominant factor causing the LET quenching effect.

Contributions to the 14. Geoengineering congress in Munich. Geoengineering with the parameters time and quality; Beitraege zum 14. Geotechnik-Tag in Muenchen. Geotechnik mit den Parametern Zeit und Qualitaet

Energy Technology Data Exchange (ETDEWEB)

Vogt, Norbert (ed.)

2016-05-01

This proceedings contains the following twelve papers: Why time and quality play a role? (Gebhard Dausch); Models for settlement prediction of structures in opencast dumps (Emanuel Birle, Stefan Vogt); Quality improvement and risk reduction through alternative proposals? Example: Intake structure of a coal-fired plant Wilhelmshaven (Thomas Brand, Friderike Hamm); History and methodology of the development of the combined pile and raft foundation (Rolf Katzenbach); Hazardous waste dump at Malsch - long-term monitoring of the safety measures (Walter Laechler, Fred Dietzel); Murphy's Law on the example of Protzenweiher Bridge (Markus Herten, Andreas Beier); ''Permanent anchor'' - state of the art and long-term experience with the durability of ground anchors (Karsten Beck House, Henning Lesemann); Optimized quality management of the implementation of DSM-works (W. Sondermann, W. Wehr); Subway construction in Doha on the example of the Green Line (Guenther Heilmayer); Marmaray Project - Bosphorus Crossing tunnels and stations - Geotechnical Aspects (Nurettin Demir); Crossrail C310 Thames Tunnel, geotechnical and tunnel construction challenges in urban tunnelling with variable ground conditions (Andreas Raedle, Stephan Assenmacher, Esters Sophia Karl); Proof concept of establishing the underground central station Stuttgart 21 - Numerical modeling and calibration (Roberto Cudmani). [German] Dieser Tagungsband enthaelt folgende zwoelf Beitraege: Warum Zeit und Qualitaet eine Rolle spielen (Gebhard Dausch); Modelle zur Setzungsprognose von Bauwerken auf Tagebaukippen (Emanuel Birle, Stefan Vogt); Qualitaetsverbesserung und Risikominimierung durch Sondervorschlaege? Beispiel: Entnahmebauwerk Kohlekraftwerk Wilhelmshaven (Thomas Brand, Friderike Hamm); Historie und Methodik der Entwicklung der Kombinierten Pfahl-Plattengruendung (KPP) (Rolf Katzenbach); Langzeitkontrolle der Sicherungsmassnahmen der Sonderabfalldeponie Malsch (Walter Laechler, Fred

Use of a dosimetric system using a SMT phototransistor in the measurement for some dosimetric parameters in conventional radiotherapy

International Nuclear Information System (INIS)

Silva, J.O. da; Magalhaes, C.M.S. de; Santos, L.A.P.

2008-01-01

For monitoring the delivered dose in the patient undergoing a cancer treatment with high-energy ionizing radiation beams is necessary to use appropriate dosimeters for the beam control quality and if it is possible, to obtain the dose information during the treatment. For this, semiconductor-based devices are used because of their high spatial resolution and to be easy to handle in spite of the ionization chambers. Nowadays the bipolar phototransistors are being proposed as ionizing radiation detectors for presenting, beyond these characteristics, the signal amplification factor (gain). So, the aim of this work is to present the use of a dosimetric system using a SMT phototransistor in the measurement for some dosimetric parameters in conventional radiotherapy: the field factor and the off-axis ratio. The phototransistors readings were compared with ones obtained from a PTW 23343 Markus chamber, under the same conditions. (author)

Do surrounding figures' emotions affect judgment of the target figure's emotion? Comparing the eye-movement patterns of European Canadians, Asian Canadians, Asian international students, and Japanese.

Science.gov (United States)

Masuda, Takahiko; Wang, Huaitang; Ishii, Keiko; Ito, Kenichi

2012-01-01

Although the effect of context on cognition is observable across cultures, preliminary findings suggest that when asked to judge the emotion of a target model's facial expression, East Asians are more likely than their North American counterparts to be influenced by the facial expressions of surrounding others (Masuda et al., 2008b). Cultural psychologists discuss this cultural variation in affective emotional context under the rubric of holistic vs. analytic thought, independent vs. interdependent self-construals, and socially disengaged vs. socially engaged emotion (e.g., Mesquita and Markus, 2004). We demonstrate that this effect is generalizable even when (1) photos of real facial emotions are used, (2) the saliency of the target model's emotion is attenuated, and (3) a specific amount of observation time is allocated. We further demonstrate that the experience plays an important role in producing cultural variations in the affective context effect on cognition.

Energy policy turnaround and agriculture. Proceedings; Energiewende und Landwirtschaft. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Wendl, Georg (ed.)

2012-11-15

Within the land-technical annual meeting at 22nd November, 2012 in the training centre of the Banz monastery (Bad Staffelstein, Federal Republic of Germany), the following lectures were held: (1) Opportunities and potentials of renewable energies in Bavaria (Rupert Schaefer); (2) Consumption of electricity and energy efficiency in agricultural operation (Stefan Neser); (3) Short-rotation plantations - Processes, efficiency and ecologic balance (Frank Burger); (4) Bavarian pilot plants for the production of biogas - Results from five years of monitoring (Mathias Effenberger); (5) Farm biomass conversion plants up to 75 kW - Opportunities and limits (Andreas Weber); (6) Photovoltaic power plants and wind power plants in the Bavarian agriculture - Where is it all going? (Johannes Graf); (7) Wind energy - Regional value creation by an area model and citizen's participation using an example in Creussen (district Bayreuth) (Harald Mild); (8) Regional power connecting using Hollfeld as an example (Markus Pirkelmann).

Summary of Session 7 'After Long Shutdown 1'

International Nuclear Information System (INIS)

Pojer, M; Schmidt, R

2012-01-01

After LS1 the energy will be about 6.5 TeV. The physics potential of LHC is determined by the integrated luminosity useful for the experiments and not only by the peak luminosity. The integrated luminosity is determined by the peak luminosity, the luminosity decay and the efficiency of operation (availability). In this session two of these parameters are addressed, the peak luminosity and the availability. Presentations related to peak luminosity: • Performance potential of the injectors after LS1, Heiko Damerau; • Performance reach of LHC after LS1, Werner Herr. Presentations related to availability: • Magnet powering with zero downtime - a dream? Markus Zerlauth; • Beam systems without failures – what can be done? Matteo Solfaroli and Jan Uythoven; • Will we still see SEEs? Marco Calviani; • UFOs – will they take over? Tobias Baer; • Quenches: will there be any? Arjan Verweij

Acute coronary syndrome associated with Churg-Strauss syndrome

Directory of Open Access Journals (Sweden)

Annette Doris Wagner

2007-11-01

Full Text Available Annette Doris Wagner1, Gerd Peter Meyer2, Markus Rihl3, Anke Rathmann2, Ulrike Wittkop1, Henning Zeidler4, Hermann Haller1, Joachim Lotz51Department Internal Medicine, Division of Nephrology; 2Division of Cardiology; 3Division of Rheumatology; 4Rheumatologikum Hannover; 5Department of Diagnostic Radiology; Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, GermanyAbstract: A 41-year old female patient was admitted with acute onset of dyspnea and chest pain. Previous history revealed asthma, chronic sinusitis and eosinophilic proctitis. Electrocardiogram showed anterior ST-segment elevations and inferior ST-segment depression. Immediate heart catheterization revealed a distally occluded left anterior descending coronary artery, the occlusion being reversible after nitroglycerine. Cardiac magnetic resonance imaging was consistent with perimyocarditis. Hypereosinophilia and IgE elevation were present and Churg-strauss syndrome was diagnosed.Keywords: Churg-Strauss syndrome (CSS, carditis, cardiac MRI

The self-schema model: a theoretical approach to the self-concept in eating disorders.

Science.gov (United States)

Stein, K F

1996-04-01

Over the last several decades, the self-concept has been implicated as a important determinant of eating disorders (ED). Although considerable progress has been made, questions remain unanswered about the properties of self-concept that distinguish women with an ED from other populations, and mechanisms that link the self-concept to the disordered behaviors. Markus's self-schema model is presented as a theoretical approach to explore the role of the self-concept in ED. To show how the schema model can be integrated with existing work on the self-concept in ED, a framework is proposed that addresses the number, content, and accessibility of the self-schemas. More specifically, it is posited that a limited collection of positive self-schemas available in memory, in combination with a chronically and inflexibly accessible body-weight self-schema, lead to the disordered behaviors associated with anorexia nervosa and bulimia nervosa.

Pancultural explanations for life satisfaction: adding relationship harmony to self-esteem.

Science.gov (United States)

Kwan, V S; Bond, M H; Singelis, T M

1997-11-01

The first part of the study confirmed an additive effect of the newly proposed construct of relationship harmony to self-esteem in predicting life satisfaction across student samples from the United States and Hong Kong. As predicted from the dynamics of cultural collectivism, the relative importance of relationship harmony to self-esteem was greater in Hong Kong than in the United States. In the second part of the study, the independent and interdependent self-construals (H. R. Markus & S. Kitayama, 1991) and the 5 factors of personality (P. T. Costa & R. R. McCrae, 1992) were advanced to be the culture-general determinants of life satisfaction, acting through the mediating variables of self-esteem and relationship harmony. Both self-construals and the 5 factors of personality were shown to influence life satisfaction through the mediating agency of self-esteem and relationship harmony in equivalent ways across these 2 cultural groups.

Science games and the development of scientific possible selves

Science.gov (United States)

Beier, Margaret E.; Miller, Leslie M.; Wang, Shu

2012-12-01

Serious scientific games, especially those that include a virtual apprenticeship component, provide players with realistic experiences in science. This article discusses how science games can influence learning about science and the development of science-oriented possible selves through repeated practice in professional play and through social influences (e.g., peer groups). We first review the theory of possible selves (Markus and Nurius 1986) and discuss the potential of serious scientific games for influencing the development of scientific possible selves. As part of our review, we present a forensic game that inspired our work. Next we present a measure of scientific possible selves and assess its reliability and validity with a sample of middle-school students ( N = 374). We conclude by discussing the promise of science games and the development of scientific possible selves on both the individual and group levels as a means of inspiring STEM careers among adolescents.

Summary of Session 7 'After Long Shutdown 1'

Energy Technology Data Exchange (ETDEWEB)

Pojer, M; Schmidt, R [European Organization for Nuclear Research, Geneva (Switzerland)

2012-07-01

After LS1 the energy will be about 6.5 TeV. The physics potential of LHC is determined by the integrated luminosity useful for the experiments and not only by the peak luminosity. The integrated luminosity is determined by the peak luminosity, the luminosity decay and the efficiency of operation (availability). In this session two of these parameters are addressed, the peak luminosity and the availability. Presentations related to peak luminosity: • Performance potential of the injectors after LS1, Heiko Damerau; • Performance reach of LHC after LS1, Werner Herr. Presentations related to availability: • Magnet powering with zero downtime - a dream? Markus Zerlauth; • Beam systems without failures – what can be done? Matteo Solfaroli and Jan Uythoven; • Will we still see SEEs? Marco Calviani; • UFOs – will they take over? Tobias Baer; • Quenches: will there be any? Arjan Verweij.

Literature in Focus: "Axions: Theory, Cosmology, and Experimental Searches"

CERN Document Server

2009-01-01

Axions are peculiar hypothetical particles that could both solve the CP problem of quantum chromodynamics and at the same time account for the dark matter of the universe. Based on a series of lectures by world experts in this field held at CERN, this volume provides a pedagogical introduction to the theory, cosmology and astrophysics of these fascinating particles and gives an up-to-date account of the status and prospect of ongoing and planned experimental searches. Learners and practitioners of astroparticle physics will find in this book both a concise introduction and a current reference work to a showcase topic that connects the "inner space" of the elementary particle world with the "outer space" of the universe at large. The book will be presented by Markus Kuster. "Axions: Theory, Cosmology, and Experimental Searches", edited by M. Kuster (Technische Universität Darmstadt), G. Raffelt (Max-Planck-Institu...

PHYSICS

CERN Multimedia

Submitted by

Physics Week: plenary meeting on physics groups plans for startup (14–15 May 2008) The Physics Objects (POG) and Physics Analysis (PAG) Groups presented their latest developments at the plenary meeting during the Physics Week. In the presentations particular attention was given to startup plans and readiness for data-taking. Many results based on the recent cosmic run were shown. A special Workshop on SUSY, described in a separate section, took place the day before the plenary. At the meeting, we had also two special DPG presentations on “Tracker and Muon alignment with CRAFT” (Ernesto Migliore) and “Calorimeter studies with CRAFT” (Chiara Rovelli). We had also a report from Offline (Andrea Rizzi) and Computing (Markus Klute) on the San Diego Workshop, described elsewhere in this bulletin. Tracking group (Boris Mangano). The level of sophistication of the tracking software increased significantly over the last few months: V0 (K0 and Λ) reconstr...

Do Surrounding Figures’ Emotions Affect Judgment of the Target Figure’s Emotion? Comparing the Eye-Movement Patterns of European Canadians, Asian Canadians, Asian International Students, and Japanese

Directory of Open Access Journals (Sweden)

Taka eMasuda

2012-09-01

Full Text Available Although the effect of context on cognition is observable across cultures, preliminary findings suggest that when asked to judge the emotion of a target model’s facial expression, East Asians are more likely than their North American counterparts to be influenced by the facial expressions of surrounding others (Masuda, Ellsworth, Mesquita, Leu, Tanida, & van de Veerdonk, 2008. Cultural psychologists discuss this cultural variation in affective emotional context under the rubric of holistic vs. analytic thought, independent vs. interdependent self-construals, and socially disengaged vs. socially engaged emotion (e.g., Mesquita & Markus, 2004. We demonstrate that this effect is generalizable even when (a photos of real facial emotions are used, (b the saliency of the target model’s emotion is attenuated, and (c a specific amount of observation time is allocated. We further demonstrate that the socialization factor plays an important role in producing cultural variations in the affective context effect on cognition.

Proceedings - COST ACTION CM1407 - 2nd Training School

Directory of Open Access Journals (Sweden)

L. Monteiro Rodrigues, et al.

2017-12-01

Full Text Available Program /Programa 18 September | 18 de Setembro Open Session | Sessão de abertura L. Monteiro Rodrigues Patrícia Rijo Bruno Botta Free Comunications | Comunicações livres Flow chemistry synthesis | Síntese de química de fluxo Chairman | Moderador - Maria M. M. Santos Speakers | Prelectores Rafael Antunes Carlos A. M. Afonso Rudi Oliveira 19 September | 19 de Setembro Free Comunications | Comunicações livres Extraction and isolation of natural products using Buchi equipments | Extração e isolamento de produtos naturais usando equipamentos Buchi Chairman | Moderador - Peter Naf Speakers | Prelectores Daniele Passarella Markus Kalesse Mattia Mori Patrícia Rijo 20 September | 20 de Setembro Free Comunications | Comunicações livres Natural products structural characterization works using the MestreNova software | Funcionamento da caracterização estrutural de produtos naturais usando o software MestreNova Chairman | Moderador - Maria José U. Ferreira Speakers | Prelectores Antonella Goggiamani Filipa Marcelo María Cecilia Carpinella

From Standard Application Packages to Enterprise Systems - A Matter of Opportunities

Science.gov (United States)

Nilsson, Anders G.

The purpose of this chapter is to make clearer the meaning behind the concepts of “standard application package” and “enterprise system.” There is today a confusion in our IS field about the connection between the two concepts and how they have appeared historically? The main idea is to contrast them against each other and in this sense to study which opportunities organizations and companies can achieve with these two different IT environments. This transparency will give business and IT people a better understanding for managing investments in information systems more professionally. The research approach is characterized as “consumable research” (Robey, and Markus, Information Resources Management Journal, 11(1): 7-15, 1998) based on theoretical knowledge integrated with business practice from the IS field. Our background is through working with practical methods for customer involvement (purchasing, implementation, maintenance) as well as performing vendor studies of the software application industry.

Geneva University

CERN Multimedia

2009-01-01

École de physique - Département de physique nucléaire et corpusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 6 avril 2009 PARTICLE PHYSICS SEMINAR àt 17:00 – Auditoire Stückelberg Hospital superbugs, nanomechanics and statistical physics Prof. Dr G. Aeppli / University College London The alarming growth of the antibiotic-resistant superbug, methicillin-resistant Staphylococcus aureus (MRSA) is driving the development of new technologies to investigate antibiotics and their modes of action. We report silicon cantilever based studies of self-assembled monolayers of mucopeptides which model drug-sensitive and resistant bacterial walls. The underlying concepts needed to understand the measurements will simplify the design of cantilevers and coatings for biosensing and could even impact our understanding of drug action on bacteria themselves. (Une verrée en compagnie du conférencier sera offerte après le colloque.) Organizer : Prof. Markus Büttiker ...

Ideas worth nurturing

CERN Multimedia

Antonella Del Rosso

2014-01-01

Originally created in response to requests from experimentalists working in the collaborations, IdeaSquare has evolved into a place where innovative ideas meet established expertise. Although the project is still in its pilot phase, two EU-funded projects have found their home in the IdeaSquare building and 46 students have already participated in the Challenge-Based Innovation courses based there. More to come…   IdeaSquare, which will be inaugurated on 9 December, is the name given to the B3179 refurbished building at LHC Point 1. More importantly, IdeaSquare is the name of a project designed to nurture innovation at CERN. “The scope of the project is to bring together researchers, engineers, people from industry and young students and encourage them to come up with new ideas that are useful for society, inspired by CERN’s ongoing detector R&D and upgrade projects,” explains Markus Nordberg who, together with Marzio Nessi, set up IdeaSquare withi...

Preliminary assessment of LiF and alanine detectors for the dosimetry of proton therapy beams

International Nuclear Information System (INIS)

Fattibene, P.; Calicchia, A.; De Angelis, C.; Onori, S.; Egger, E.

1996-01-01

An experimental intercomparison between the proton response of LiF TLD-100 and alanine detectors is reported. The investigations were performed with LiF chips and alanine pellets in a 62 MeV proton beam at the Paul Scherrer Institut in Villigen (CH). Results were compared with reference dosimetry provided by Markus type parallel plate ionization chamber. The response of the detectors was studied, in a phantom, at different beam penetration depths in pristine and modulated beams. For both alanine and TL detectors, within the experimental uncertainty of the measurements, no significant energy dependence in the response was observed down to the Bragg peak region. The sensitivity of alanine and LiF detectors to protons was measured in the centre of modulated Bragg peak and no significant difference was found with respect to 60 Co. Contrary to LiF, alanine also offers a remarkable tissue equivalence which favours its choice for in-phantom dosimetry. (author)

CAS course on Power Converters in Baden, Switzerland

CERN Multimedia

CERN Accelerator School

2014-01-01

The CERN Accelerator School (CAS) and the Paul Scherrer Institute (PSI) recently organised a specialised course on Power Converters, which was held at the Hotel du Parc in Baden, Switzerland from 7 to 14 May 2014.   Photo courtesy of Markus Fischer, Paul Scherrer Institut. Following some recapitulation lectures on accelerators and the requirements on power converters, the course covered a wide range of topics related to the different types of power converters needed for particle accelerators. Topical seminars completed the programme. The course was very successful, attended by 84 students representing 21 nationalities, mostly from European countries but also from America, Brazil, Canada, China, Iran, Jordan and Thailand. Feedback from the participants was very positive, reflecting the high standard of the lectures and teaching. In addition to the academic programme, the participants also had an opportunity to take part in a full-day site visit to ABB and PSI and an excursion to the Rhine Fall...

Versatile by design

CERN Multimedia

Katarina Anthony

2014-01-01

CHARM (CERN High energy AcceleRator Mixed field) is a new and unique testing facility that will complete CERN's radiation testing installations. Located in the East Area, CHARM will provide teams with a venue to test their equipment in radiation environments similar to those found in the accelerator chain.   Team at work in the irradiation zone of the CHARM facility. First envisaged in 2007, the CHARM facility fulfils a growing demand for a large-scale tailor-made radiation testing facility. Unlike commercial facilities, CHARM features a wide spectrum of radiation types and energies (called mixed-field radiation environments), the space to test large equipment and even the possibility to adjust the environment using mobile shielding. "CHARM is versatile by design, allowing us to recreate any of the radiation environments found in the accelerator chain," says Markus Brugger, head of the R2E (Radiation to Electronics) project team that developed the CHARM facility. &a...

Lévy matters IV estimation for discretely observed Lévy processes

CERN Document Server

Belomestny, Denis; Genon-Catalot, Valentine; Masuda, Hiroki; Reiß, Markus

2015-01-01

The aim of this volume is to provide an extensive account of the most recent advances in statistics for discretely observed Lévy processes. These days, statistics for stochastic processes is a lively topic, driven by the needs of various fields of application, such as finance, the biosciences, and telecommunication. The three chapters of this volume are completely dedicated to the estimation of Lévy processes, and are written by experts in the field. The first chapter by Denis Belomestny and Markus Reiß treats the low frequency situation, and estimation methods are based on the empirical characteristic function. The second chapter by Fabienne Comte and Valery Genon-Catalon is dedicated to non-parametric estimation mainly covering the high-frequency data case. A distinctive feature of this part is the construction of adaptive estimators, based on deconvolution or projection or kernel methods. The last chapter by Hiroki Masuda considers the parametric situation. The chapters cover the main aspects of the est...

Atmospheric and aerosol chemistry

International Nuclear Information System (INIS)

McNeill, V. Faye; Ariya, Parisa A.; McGill Univ. Montreal, QC

2014-01-01

This series presents critical reviews of the present position and future trends in modern chemical research. Short and concise reports on chemistry, each written by the world renowned experts. Still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. Christian George, Barbara D'Anna, Hartmut Herrmann, Christian Weller, Veronica Vaida, D. J. Donaldson, Thorsten Bartels-Rausch, Markus Ammann Emerging Areas in Atmospheric Photochemistry. Lisa Whalley, Daniel Stone, Dwayne Heard New Insights into the Tropospheric Oxidation of Isoprene: Combining Field Measurements, Laboratory Studies, Chemical Modelling and Quantum Theory. Neil M. Donahue, Allen L. Robinson, Erica R. Trump, Ilona Riipinen, Jesse H. Kroll Volatility and Aging of Atmospheric Organic Aerosol. P. A. Ariya, G. Kos, R. Mortazavi, E. D. Hudson, V. Kanthasamy, N. Eltouny, J. Sun, C. Wilde Bio-Organic Materials in the Atmosphere and Snow: Measurement and Characterization V. Faye McNeill, Neha Sareen, Allison N. Schwier Surface-Active Organics in Atmospheric Aerosols.

A motivação de professores de inglês de escola pública: o que as teorias do “eu” podem nos dizer?

Directory of Open Access Journals (Sweden)

Fernanda Costa Ribas

2013-03-01

Full Text Available Neste artigo, apresento resultados de uma pesquisa qualitativa em andamento, realizada com dois professores de inglês de ensino fundamental de uma escola pública de Minas Gerais. Procuro investigar a motivação desses professores à luz das teorias do ‘eu’ (MARKUS; NURIUS, 1986; HIGGINS, 1987. Os métodos de coleta de dados incluem um questionário, uma entrevista, notas de campo e sessões de visionamento. Os resultados mostram o importante papel exercido por autocrenças positivas e negativas (tanto atuais como futuras no fluxo motivacional do professor. Concluo o artigo enfatizando a necessidade de encorajar a reflexão sobre autocrenças e fatores afetivos que impactam na ação, bem como o compartilhamento de experiências em programas de formação inicial e continuada de professores, de forma a engendrar um ciclo motivacional positivo nas escolas.

Energy and emissions trading. Proceedings; Energie und Klimawandel. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Ehlers, Dirk; Wolffgang, Hans-Michael; Schroeder, Ulrich Jan (eds.)

2010-07-01

Within the 14th Muensteraner Foreign Trade legislation conference at 15th and 16th October, 2009 in Muenster (Federal Republic of Germany), the following lectures were held: (1) National and European energy policy (Dieter Kunhenn); (2) Trade, transport and distribution of energy - actual and future legal aspects (Markus J. Kachel); (3) Liberalization and regulation of energy services at multilateral and bilateral level (Christian Pitschas); (4) Legal protection for foreign direct investigations in the energy sector (Richard Kreindler); (5) Energy cartels in the light of the WTO law (Joerg Philipp Terhechte); (6) Subsidisation of renewable energy in the area of attention between WTO and EU subsidy law (Martin Lukas); (7) Legal aspects of pipeline through the Baltic Sea (Barbara Kaech); (8) Sustainability standards and their compatibility with the WTO law (Lorenz Franken); (9) Economic instruments between Kyoto and Kopenhagen - Quo vadis climate protection? (Benjamin Goeerlach); (10) Emissions rights trading with developing countries (Peter Ebsen); (11) Legal aspects of the European emissions rights trading (Stefan Altenschmidt).

Meresõiduohutus, kontroll ja järelevalve : [bakalaureusetöö] / Margit Markus ; Tartu Ülikool, õigusteaduskond ; juhendaja: Tanel Kerikmäe

Index Scriptorium Estoniae

Markus, Margit

1999-01-01

Meresõiduohutus - mõisted ja määratlused, rahvusvahelised meresõiduohutust reguleerivad aktid (konventsioonid, SOLAS, MARPOL, LL, COLREG), meresõiduohutuse alane kontroll ja järelevalve, laevade klassifitseerimine ja klassifikatsiooniühingud, vastutus

LET dependence of GafChromic films and an ion chamber in low-energy proton dosimetry

Energy Technology Data Exchange (ETDEWEB)

Kirby, Daniel; Parker, David [School of Physics and Astronomy, University of Birmingham, Birmingham, B15 2TT (United Kingdom); Green, Stuart; Hugtenburg, Richard; Wojnecki, Cecile [Department of Medical Physics, University Hospital Birmingham NHS Trust, Birmingham, B15 2TH (United Kingdom); Palmans, Hugo [National Physical Laboratory, Acoustics and Ionizing Radiation, Teddington (United Kingdom)], E-mail: djk191@bham.ac.uk

2010-01-21

Dosimetry using a PMMA phantom was performed in 15 and 29 MeV proton beams from the Birmingham cyclotron, with a Markus parallel-plate ionization chamber and GafChromic EBT and MD-V2-55 film. Simulations of the depth-dose curves were performed with FLUKA 2008.3 and MCNPX 2.5.0, which agreed almost perfectly with each other in range and only differed by 2% in the Bragg peak (BP) region. FLUKA was also used to calculate k{sub Q} factors for Markus chamber measurements as an improvement to the IAEA TRS-398 values in low-energy beams. FLUKA depth-dose simulations overestimate the BP height measured by ion chamber by about 10%, where the initial proton energy spread was estimated by fitting to the slope of the measured BP distal edge. Both GafChromic films showed an under-response in the BP compared to ion chamber; however, EBT exhibits this effect at lower energies than MD-V2-55. A possible reason for this is attributed to the shape and arrangement of the monomer particles being different in the active components of EBT and MD-V2-55. Relative effectiveness (RE) of both films is presented as functions of residual range R{sub res} in water and peak proton energy determined by FLUKA, with considerations for the spatial separation of the two active layers in each film. The proton energies at which RE reduces to 90% of maximum film response are 6.7 and 3.2 MeV for MD-V2-55 and EBT, respectively. Additionally, a beam quality correction factor (g{sub Q,Q{sub 0}}) is suggested for both GafChromic films, involving water-to-film stopping power ratios evaluated using ICRU recommendations, and a polymer yield factor G{sub Q{sub 0}}/G{sub Q}. RE in this work is equated to the reciprocal of the polymer yield factor. The calculated values of (s{sub w,film}){sub Q} /(s{sub w,film}){sub Q{sub 0}} are constant within 2.1% and 1.2% across the proton energy range of 1-300 MeV for EBT and MD-V2-55, respectively, so it is concluded that the polymer yield factor is the dominant factor

The Effect of Aquaplast on Surface Dose of Photon Beam

International Nuclear Information System (INIS)

Oh, Do Hoon; Bae, Hoon Sik

1995-01-01

Purpose : To evaluate the effect on surface dose due to Aquaplast used for immobilizing the patients with head and neck cancers in photon beam radiotherapy. Materials and Methods : To assess surface and buildup region dose for 6MV X-ray from linear accelerator(Siemens Mevatron 6740), we measured percent ionization value with the Markus chamber model 30-329 manufactured by PTW Frieburg and Capintec electrometer, model WK92. For measurement of surface ionization value, the chamber was embedded in 25 X 25 X 3 cm 3 acrylic phantom and set on 25 X 25 X 5 cm 3 , polystyrene phantom to allow adequate scattering. The measurements of percent depth ionization were made by placing the polystyrene layers of appropriate thickness over the chamber. The measurements were taken at 10 cm SSD for 5 X 5 cm 2 , 10 X 10 cm 2 , and 15 X 15 cm 2 field sizes, respectively. Placing the layer of Aquaplast over the chamber, the same procedures were repeated. We evaluated two types o Aquaplast: 1.6mm layer of original Aquaplast(manufactured by WFR Aquaplast Corp.) and transformed Aquaplast similar to moulded one for immobilizing the patients practically. We also measured surface ionization values with blocking tray in presence or absence of transformed Aquaplast. In calculating percent depth dose, we used the formula suggested by Gerbi and khan to correct over response of the Markus chamber. Results : The surface doses for open fields of 5 X 5 cm 2 , 10 X 10 cm 2 , 15 X 15 cm 2 were 7.9%, 13.6%, and 18.7% respectively. He original Aquaplast increased the surface doses upto 38.4%, 43.6% and 47.4% respectively. There were little differences in percent depth dose values beyond the depth of Dmax. Increasing field size, the blocking tray caused increase of the surface dose by 0.2%, 1.7%, 3.0% without Aquaplast, 0.2%, 1.9%, 3.7% with transformed Aquaplast, respectively. Conclusion : The original and transformed Aquaplast increased the surface dose moderately. The percent depth doses beyond Dmax

Atmospheric and aerosol chemistry

Energy Technology Data Exchange (ETDEWEB)

McNeill, V. Faye [Columbia Univ., New York, NY (United States). Dept. of Chemical Engineering; Ariya, Parisa A. (ed.) [McGill Univ. Montreal, QC (Canada). Dept. of Chemistry; McGill Univ. Montreal, QC (Canada). Dept. of Atmospheric and Oceanic Sciences

2014-09-01

This series presents critical reviews of the present position and future trends in modern chemical research. Short and concise reports on chemistry, each written by the world renowned experts. Still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. Christian George, Barbara D'Anna, Hartmut Herrmann, Christian Weller, Veronica Vaida, D. J. Donaldson, Thorsten Bartels-Rausch, Markus Ammann Emerging Areas in Atmospheric Photochemistry. Lisa Whalley, Daniel Stone, Dwayne Heard New Insights into the Tropospheric Oxidation of Isoprene: Combining Field Measurements, Laboratory Studies, Chemical Modelling and Quantum Theory. Neil M. Donahue, Allen L. Robinson, Erica R. Trump, Ilona Riipinen, Jesse H. Kroll Volatility and Aging of Atmospheric Organic Aerosol. P. A. Ariya, G. Kos, R. Mortazavi, E. D. Hudson, V. Kanthasamy, N. Eltouny, J. Sun, C. Wilde Bio-Organic Materials in the Atmosphere and Snow: Measurement and Characterization V. Faye McNeill, Neha Sareen, Allison N. Schwier Surface-Active Organics in Atmospheric Aerosols.

Conference on raw materials and jobs cost variation - Impact on wind turbine manufacturers and operators

International Nuclear Information System (INIS)

Chabot, Bernard; Falk, Thorsten; Braeuninger, Michael; Rehfeldt, Knud; Brand, Ruth; Buhr, Ingo de; Jenne, Markus

2007-01-01

In the framework of the 2007 Husum Wind exhibition, the French-German office for Renewable energies (OFAEnR) organised a side event on In the framework of this French-German exchange of experience, participants exchanged views on raw materials and jobs cost variations in the wind power industry in both countries. Its aim was to compare and analyse the French and German respective support systems to renewable energy sources. This document brings together the available presentations (slides) made during this event: 1 - Protecting wind energy tariffs against inflation effects: analysis and suggestions from the French experience (Bernard Chabot); 2 - Wind energy in Germany - Tariff structure in the EEG renewable energy law (Thorsten Falk); 3 - Wind energy competitiveness (Michael Braeuninge, Knud Rehfeldt); 4 - Influence of raw materials price rise on the production costs of ENERCON wind turbines maker (Ruth Brand); 5 - Presentation of the overall costs of an offshore wind energy project (Ingo de Buhr); 6 - Comparison between French and German tariffs profitability using a model wind farm: presentation of the pros and cons of both systems (Markus Jenne)

Resveratrol in prevention and treatment of common clinical conditions of aging

Directory of Open Access Journals (Sweden)

M Andrea Markus

2008-06-01

Full Text Available M Andrea Markus, Brian J MorrisSchool of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, NSW, AustraliaAbstract: Resveratrol is a potent member of the class of natural, plant-derived chemicals known as polyphenols. These help explain in part why a diet high in fruit and vegetables confers health benefits and are associated with reduced risk of common complex conditions such as cardiovascular disease, cancer, diabetes, and Alzheimer’s disease. We present the latest molecular findings that account for the beneficial actions of resveratrol. The intracellular pathways activated are crucial for anti-oxidant defence, regulation of the cell cycle, mitochondrial energy production, vascular tone, oncogene suppression, and many other phenomena which if unchecked lead to morbidity and mortality from onset and progression of these various diseases. While a healthy diet and lifestyle is strongly recommended in prevention of such conditions, the future bodes well for the use of resveratrol and analogues of higher potency than the natural form for treatment of diseases that afflict humans, particularly as they age.Keywords: resveratrol, longevity, SIRT, wine, aging, cancer

Registrations open for ISOTDAQ 2013

CERN Multimedia

2012-01-01

The 4th edition of the International School on Trigger and Data Acquisition (ISOTDAQ 2013) will be held in Thessaloniki, Greece, from 1 to 8 February.   The target audience is Physics and Engineering MSc and PhD students as well as practising scientists with an interest in Trigger and Data Acquisition. The school provides an up-to-date overview of the basic instruments and methods used in high energy physics DAQ systems, spanning small experiments to the very large ones at the LHC.  As in previous years (see here and here) half of the time will be dedicated to lectures that will be given by experts from CERN and other institutes. The other half of the programme is a comprehensive set of hands-on exercises that will allow the students to work on real DAQ hardware in small groups under the supervision of experienced tutors. Applications are accepted until 1 December. For further details please visit the school's Web site. Markus Joos on behalf of the organizers

Medizinbibliotheken: Innovativ denken, strategisch planen, praktisch umsetzen / Medical libraries: think innovative, plan strategically, implement in practice

Directory of Open Access Journals (Sweden)

Bauer, Bruno

2011-12-01

Full Text Available The focus of the current issue 3/2011 of GMS Medizin – Bibliothek – Information is the annual conference 2011 of the German Medical Libraries Association in Cologne. The motto of the conference was “Think innovative, plan strategically, implement in practice”. Focal points of the meeting were innovation management, marketing and new applications in medical libraries.The authors in this issue are Bruno Bauer, Daniel Formanek & Helmut Dollfuß (E-Books at medical libraries: They came to stay, Ursula Georgy (Systematic innovation management, Maurizio Grilli (New library portal at Province College for Health-Care Professions Claudiana, Bozen, Sabine Köhrer-Weisser (Marketing in One Person Libraries, Roland Mumenthaler (Innovation Management at ETH-Bibliothek, Markus Schmiel (Performance-related bonuses at Hannover Medical School: practical experience report of the library, Guus van den Brekel (Mobile Computing & Semantic Web in Health & Medicine, Iris Reimann & Sonja Fräntz (Think innovative, plan strategically, implement in practice – Annual Meeting 2011 of the German MLA, 19th to 21th September in Cologne and Eike Hentschel (Aus der AGMB.

Université de Genève

CERN Multimedia

2008-01-01

Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 8 décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium The Galaxy in a new light: High energy gamma ray astronomy with H.E.S.S. Prof. Werner Hofmann / MPI für Kernphysik, Heidelberg During its first years of operation, the H.E.S.S. array of imaging atmospheric Cherenkov telescopes has revealed a sky full of sources of very high energy gamma rays and has demonstrated the great power of the Cherenkov technique for exploring non-thermal processes in the Universe. High-energy gamma ray astronomy is now delivering sky maps, sources with resolved morphology, and high-resolution light curves, joining up with mainstream astronomy. The talk will illustrate some of the key results from H.E.S.S., mention some of the open questions, and present ideas for the next-generation CTA observatory. Organizer : Prof. Markus Büttiker W...

Review of data and methods recommended in the international code of practice for dosimetry IAEA Technical Reports Series No. 381, The Use of Plane Parallel Ionization Chambers in High Energy Electron and Photon beams. Final report of the co-ordinated research project on dose determination with plane parallel ionization chambers in therapeutic electron and photon beams

International Nuclear Information System (INIS)

Dusautoy, A.; Roos, M.; Svensson, H.; Andreo, P.

2000-01-01

An IAEA Co-ordinated Research Project was designed to validate the data and procedures included in the International Code of Practice Technical Reports Series (TRS) No. 381, ''The Use of Plane Parallel Ionization Chambers in High Energy Electron and Photon Beams''. This work reviews and analyses the procedures used and the data obtained by the participants of the project. The analysis shows that applying TRS-381 generally produces reliable results. The determination of absorbed dose to water using the electron method in reference conditions is within the stated uncertainties (2.9%). Comparisons have shown TRS-381 is consistent with the AAPM TG-39 protocol within 1% for measurements made in water. Based on the analysis, recommendations are given with respect to: (i) the use of plane parallel ionization chambers of the Markus type, (ii) the values for the fluence correction factor for cylindrical chambers, (iii) the value of the wall correction factor for the Roos chamber in 60 Co beams, and (iv) the use of plastic phantoms and the values of the fluence correction factors. (author)

R2E – identifying problems, mitigating risks

CERN Document Server

Anaïs Schaeffer

2013-01-01

During LS1, the R2E project team will be working on a task as painstaking as it is crucial: to achieve a sixfold reduction in the number of electronic malfunctions caused by radiation. On their success depends the ability of the accelerator to function correctly at nominal energy. No mean challenge, considering it comes on top of the tenfold reduction already achieved since 2009.   The graph plots the rate of LHC beam dumps due to single-event effects against beam luminosity. An indication of the challenge that faces the R2E project teams during LS1! The origins of the project known as R2E (Radiation to Electronics) go back to 2007, when the CNGS (CERN Neutrinos to Gran Sasso) experiment was being commissioned. "Right from the outset, some CNGS control systems were causing problems. They would regularly break down in operations with beam," recalls Markus Brugger, head of the R2E project. "Even though the beam intensity was very low, we began to suspect that radiati...

Dosimetric accuracy of a treatment planning system for actively scanned proton beams and small target volumes: Monte Carlo and experimental validation

CERN Document Server

Magro, G; Mairani, A; Mirandola, A; Panizza, D; Russo, S; Ferrari, A; Valvo, F; Fossati, P; Ciocca, M

2015-01-01

This study was performed to evaluate the accuracy of a commercial treatment planning system (TPS), in optimising proton pencil beam dose distributions for small targets of different sizes (5–30 mm side) located at increasing depths in water. The TPS analytical algorithm was benchmarked against experimental data and the FLUKA Monte Carlo (MC) code, previously validated for the selected beam-line. We tested the Siemens syngo® TPS plan optimisation module for water cubes fixing the configurable parameters at clinical standards, with homogeneous target coverage to a 2 Gy (RBE) dose prescription as unique goal. Plans were delivered and the dose at each volume centre was measured in water with a calibrated PTW Advanced Markus® chamber. An EBT3® film was also positioned at the phantom entrance window for the acquisition of 2D dose maps. Discrepancies between TPS calculated and MC simulated values were mainly due to the different lateral spread modeling and resulted in being related to the field-to-spot size r...

Deceased Slabs Drive Oil

Science.gov (United States)

Stein, H. J.; Hannah, J. L.

2017-12-01

.V., Stein, H.J., and Hannah, J.L. (in review) Re-Os in oil - in the company of water. [4] Fichler, C., Odinsen, T., Rueslåtten, H., Olesen, O., Vingstad, J.-E., Wienecke, S. (2011) Crustal inhomogenities in the northern North Sea from potential field modeling: inherited structure and serpentinites: Tectonophysics 510: 172-185. [doi:10.1016/j.tecto.2011.06.026

3. forum bioenergy. Politics, market, finances, marketing and distribution, export. Proceedings 2007; 3. Forum Bioenergie. Politik, Markt, Finanzierung, Marketing and Vertrieb, Export. Tagungsband 2007

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

The following lectures were held (selection of topics): The decision to the thermal energy law and EEG from the cabinet meeting at 5th December, 2007 (Heiko Schwarzburger); Comment of the opposition to the cabinet decisions and outline of the political activities of the European policy (Heinz-Josef Fell); The meaning of new systems for utilization of land for soil protection and climatic change (Uwe Schneider); State of the art: laws and terms of references (Lothar Breidenbach); Bioenergy the interface industry - strategic challenges (Hilmar Platz); Actual developments with the promotion of the bioenergy by EEG and thermal energy law (Nicole Pippke); National biomass strategies in the European Union - project BAP DRIVER (Alexandra Lermen); Effects of the trade from biofuels to meet the development extensions of the European Union on area requirements (Enver Doruk Oezdemir); Energy region Rhein-Sieg: Renewable energies in the association - modelling of self-sufficient regions (Rolf Beyer); Potentials of value added in regions - results from the BMU project BioRegio (Georg Wagener Lohse); Posibilities and terms of references for increasing the potentials of biomass (Cornelia Behm); What can bioenergies perform in mix of renewable energies? - Discussion contribution for the limited potential of the bio energies (Susanne Jung); Panel discussion with representatives from the policy: Surface competition - full grain instead of full power; Fermentation gas - economy and experiences from bank view (Joerg-Uwe Fischer); Financing concept of large-scale projects by the example of the biological gas facility in Penkun (Balthasar Schramm); Economy factors for the gas feed - examples from consultant practice (Markus Helm); Stabilization or endangerment agriculture? Realizations from the field study 'biological gas facilities in Bavaria' (Wilfried Zoerner); Bioenergy - chances for investors (Daniel Kellermann); Private Equity within the range of bioenergy (Andrew Murphy

An abstract approach to some spectral problems of direct sum differential operators

Directory of Open Access Journals (Sweden)

Maksim S. Sokolov

2003-07-01

Full Text Available In this paper, we study the common spectral properties of abstract self-adjoint direct sum operators, considered in a direct sum Hilbert space. Applications of such operators arise in the modelling of processes of multi-particle quantum mechanics, quantum field theory and, specifically, in multi-interval boundary problems of differential equations. We show that a direct sum operator does not depend in a straightforward manner on the separate operators involved. That is, on having a set of self-adjoint operators giving a direct sum operator, we show how the spectral representation for this operator depends on the spectral representations for the individual operators (the coordinate operators involved in forming this sum operator. In particular it is shown that this problem is not immediately solved by taking a direct sum of the spectral properties of the coordinate operators. Primarily, these results are to be applied to operators generated by a multi-interval quasi-differential system studied, in the earlier works of Ashurov, Everitt, Gesztezy, Kirsch, Markus and Zettl. The abstract approach in this paper indicates the need for further development of spectral theory for direct sum differential operators.

Cultural values and performance appraisal: assessing the effects of rater self-construal on performance ratings.

Science.gov (United States)

Mishra, Vipanchi; Roch, Sylvia G

2013-01-01

Much of the prior research investigating the influence of cultural values on performance ratings has focused either on conducting cross-national comparisons among raters or using cultural level individualism/collectivism scales to measure the effects of cultural values on performance ratings. Recent research has shown that there is considerable within country variation in cultural values, i.e. people in one country can be more individualistic or collectivistic in nature. Taking the latter perspective, the present study used Markus and Kitayama's (1991) conceptualization of independent and interdependent self-construals as measures of individual variations in cultural values to investigate within culture variations in performance ratings. Results suggest that rater self-construal has a significant influence on overall performance evaluations; specifically, raters with a highly interdependent self-construal tend to show a preference for interdependent ratees, whereas raters high on independent self-construal do not show a preference for specific type of ratees when making overall performance evaluations. Although rater self-construal significantly influenced overall performance evaluations, no such effects were observed for specific dimension ratings. Implications of these results for performance appraisal research and practice are discussed.

APLIKASI Z-SCORE METHOD DALAM PEMBENTUKAN PORTOFOLIO

Directory of Open Access Journals (Sweden)

Deannes Isynuwardhana

2017-03-01

Full Text Available The problem that often occurs in forming portfolio was regarding the selection and weighting the stock wichhad to be included in portfolio. This study attempted to solve the problem by using a simple model, which wasexpected to be applied easily by investors. This was a descriptive research with quantitative approach, andused stocks that was categorized as “blue chip” in Indonesia’s stock exchange as a sample. Stock selectionprocess used Z-score method with 6 criteria. There were, price earning ratio, price to book value, debt to equityratio, gross profit margin, return on equity, and stock’s historical price. The weighting of each stock inportfolio was then calculated by were used Bodie, Kane, and Markus (2011 approach. The coefficient ofvariation, risk and return of the market used as benchmark to measure portfolio performance. The result showedthat portfolio which formed by Z-score method give higher return than the market. Although the portfolioprovided greater risk, but it was not comparable with the marker return that gave negative results in return.The result suggested that portfolio which was created using the Z-score method could be applied by investorsin Indonesia’s stock exchange.

Perceived parenting styles differ between genders but not between elite athletes and controls

Directory of Open Access Journals (Sweden)

Serge Brand

2011-01-01

Full Text Available Serge Brand1, Markus Gerber2, Johannes Beck1, Nadeem Kalak1, Martin Hatzinger1,3, Uwe Pühse2, Edith Holsboer-Trachsler11Depression and Sleep Research Unit, Psychiatric Hospital of the University of Basel, Basel, Switzerland; 2Institute of Exercise and Health Sciences, University of Basel, Basel, Switzerland; 3Psychiatric Hospital, Solothurn, SwitzerlandAbstract: For adolescent elite athletes, parental financial and emotional support is crucial. However, parents of elite athletes may be critical and demanding. Moreover, there is evidence that girls report more favorable perceived parenting styles compared with boys. The aim of the present study was to investigate perceived parenting styles among female and male adolescent elite athletes and controls. We sampled 258 adolescent elite athletes (139 females, 119 males and 176 controls (139 females, 37 males. Participants completed a questionnaire to assess perceived parenting styles (support, commendation, reproach, restriction, inconsistency. Results showed that parenting styles did not differ between athletes and controls, except for restriction, for which athletes reported lower levels. Female adolescents had higher scores for positive and lower scores for negative perceived parenting styles.Keywords: parenting style, gender, elite athletes, controls

Environmental political targets of the EU: German-French contributions for the achievement of the EU goals. Proceedings; Umweltpolitische Ziele der EU: Deutsch-franzoesische Beitraege zur Zielerreichung. Concepts franco-allemands pour atteindre les objectifs environnementaux de l'UE. Tagungsband. Actes

Energy Technology Data Exchange (ETDEWEB)

Cail, Sylvain; Moest, Dominik; Fichtner, Wolf; Percebois, Jacques (eds.)

2009-07-01

The first German-French workshop on energy economy and sustainability on January 29 and 30, 2009 at Karlsruhe (Federal Republic of Germany) comprised the following lectures: (1) Systematic evaluation of the sustainability in energy projects (Volker Stelzer); (2) Comparative value of various mechanisms of promoting renewable energy sources (Jacques Percebois, Olivier Rousse); (3) Communities as actors in climate protection (Lioba Markl, Nurten Avci); (4) The chain of value of photovoltaic systems containing crystalline silicon (Christin Oeser); (5) The wind power industry as an example of the German-French cooperation for the achievement of environmental political targets of the EU (Katharina Braig, Markus Jenne); (6) A short history of the future of biomass and biofuels in relation to white biotechnologies (Gerard Goma, Carole Molina-Jouve); (7) Generation and feeding of methane from biomass (Frank Graf); (8) Energy evaluation of the thickening of the biomass by rapid pyrolysis (Guillain Mauviel et al.); (9) Future role of renewable energies in European electricity supply (Dominik Moest et al.); (10) A systematic evaluation of the potentials for reducing CO{sub 2} as an element of company management (Sarah Schwarz); (11) A system dynamics model of the German electricity market (Tobias Jaeger).

Drawing Myth and History in visual art

Directory of Open Access Journals (Sweden)

Jaime de Córdoba

2009-07-01

Full Text Available After the famous exhibition “Copier créer” curated by Jean Pierre Cuzin in the “Musée du Louvre” in 1993, the practice of drawing art has acquired a renovated interest. This exhibition revised the theoretical concepts introduced by Bober and others in the second half of the XXth century and increased the value of the contribution of drawing in the study of art history instead of the idea of copying. An important catalog and essay by Haverkamp, Begemann and Login, titled “Creative copies”, appeared in 1988 and contained the best examples of the main collections. The last but not least important consequence was the collaboration between international museums, using their own spaces, with contemporary artists. The hermeneutic drawings and paintings by Markus Lüpertz in the Munich Glyptotheck and the exhibition of Giacometti’s drawings shown in the IVAM in 2000 are two excellent examples of the European relevance in this field. I want to analyze here twenty years of drawing done in different museums and institutions around the world and its close relationship with the process of recovering our historical memory by using visual art.

Contributions to the 14. Geoengineering congress in Munich. Geoengineering with the parameters time and quality

International Nuclear Information System (INIS)

Vogt, Norbert

2016-01-01

This proceedings contains the following twelve papers: Why time and quality play a role? (Gebhard Dausch); Models for settlement prediction of structures in opencast dumps (Emanuel Birle, Stefan Vogt); Quality improvement and risk reduction through alternative proposals? Example: Intake structure of a coal-fired plant Wilhelmshaven (Thomas Brand, Friderike Hamm); History and methodology of the development of the combined pile and raft foundation (Rolf Katzenbach); Hazardous waste dump at Malsch - long-term monitoring of the safety measures (Walter Laechler, Fred Dietzel); Murphy's Law on the example of Protzenweiher Bridge (Markus Herten, Andreas Beier); ''Permanent anchor'' - state of the art and long-term experience with the durability of ground anchors (Karsten Beck House, Henning Lesemann); Optimized quality management of the implementation of DSM-works (W. Sondermann, W. Wehr); Subway construction in Doha on the example of the Green Line (Guenther Heilmayer); Marmaray Project - Bosphorus Crossing tunnels and stations - Geotechnical Aspects (Nurettin Demir); Crossrail C310 Thames Tunnel, geotechnical and tunnel construction challenges in urban tunnelling with variable ground conditions (Andreas Raedle, Stephan Assenmacher, Esters Sophia Karl); Proof concept of establishing the underground central station Stuttgart 21 - Numerical modeling and calibration (Roberto Cudmani). [de

Controllability of linear vector fields on Lie groups

International Nuclear Information System (INIS)

Ayala, V.; Tirao, J.

1994-11-01

In this paper, we shall deal with a linear control system Σ defined on a Lie group G with Lie algebra g. The dynamic of Σ is determined by the drift vector field which is an element in the normalizer of g in the Lie algebra of all smooth vector field on G and by the control vectors which are elements in g considered as left-invariant vector fields. We characterize the normalizer of g identifying vector fields on G with C ∞ -functions defined on G into g. For this class of control systems we study algebraic conditions for the controllability problem. Indeed, we prove that if the drift vector field has a singularity then the Lie algebra rank condition is necessary for the controllability property, but in general this condition does not determine this property. On the other hand, we show that the rank (ad-rank) condition is sufficient for the controllability of Σ. In particular, we extend the fundamental Kalman's theorem when G is an Abelian connected Lie group. Our work is related with a paper of L. Markus and we also improve his results. (author). 7 refs

Lastekirjandus 2008 kurja kriitiku pilgu läbi / Ilona Martson

Index Scriptorium Estoniae

Martson, Ilona, 1970-

2009-01-01

Ülevaade 2008. aasta eesti lastekirjandusest. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Piret Raud "Printsess Luluu", Aino Pervik "Presidendilood", Kristiina Kass "Petra lood", Kätlin Vainola "Mia, Konrad ja avanevad uksed", Kerttu Soans "Külaline vannis", Wimberg "Härra Padakonn", Leelo Tungal "Seltsimees laps", Kadri Hinrikus "Miia ja Friida", Ivar Soopan "Kõik poisid ei saa suureks", Siiri Laidla "Raamatukogunõid Rosaalie", Siiri Laidla "Armas hunt", Reeli Reinaus "Saladuslik päevik", Tiia Selli "Neletriin ja Kapi-Kaarup", Markus Saksatamm "Võlur Sinku-Vinku ja nõiatrall", Evelin Samuel "Ükskord, kui sadas vihma", Mikä Keränen "Varastatud oranž jalgratas", Ivo Parbus "Draakon Rudolf", Urmas Nemvalts "Väikeste meeste lennumasinajutud", Lehte Hainsalu "Väike valge", Jaan Tangsoo "Mina ja minu pere", Aidi Vallik "Pints ja Tutsik", Heiki Vilep "Horlok ja Ürgvärava võti", Evelin Samuel "Hiigelsoojad pilvelambad", Sulev Oll "Hea tuju kuju", Paul-Eerik Rummo "Kui lähed teele koidu eel", Heljo Mänd "Suve suurmüük", Heljo Mänd "Sügise süda", Heljo Mänd "Kevade reklaam", Heljo Mänd "Talve Top", Ülo Pikkov. Presidendi torukübar

The nuclear phase-out and its consequences

International Nuclear Information System (INIS)

Ludwigs, Markus

2016-01-01

As a lesson from the Fukushima nuclear disaster, a radical change has taken place in climate and energy policy in Germany since 2011. This is characterized by the phase-out of the nuclear energy, which is fixed by the 13th Atomic Enforcement Act, by the end of 2022. This entails a multitude of complex legal questions and subsequent problems. The latest decisions are the forthcoming decisions of the BVerfG on the constitutional consistency of the nuclear phase-out law and nuclear fuel tax, Vattenfall's much discussed arbitration award before the ICSID arbitration court, and controversial legal questions both in the context of the decommissioning and dismantling of nuclear power plants and the disposal of highly radioactive waste. In addition, the moral-ethical evaluation of the nuclear phase-out and the power turn-around is the focus of the interdisciplinary approach. The problem clusters are analyzed by the contributions of the anthology. He documents a conference organized by Professor Dr. Markus Ludwig, which took place on April 8, 2016, at the University of Wuerzburg, within the framework of a project funded by the Fritz Thyssen Stiftung (''The Law of the Energy Transition''). [de

Frequency and clinical relevance of human bocavirus infection in acute exacerbations of chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

Felix C Ringshausen

2009-02-01

Full Text Available Felix C Ringshausen1, Ai-Yui M Tan1, Tobias Allander2, Irmgard Borg1, Umut Arinir1, Juliane Kronsbein1, Barbara M Hauptmeier1, Gerhard Schultze-Werninghaus1, Gernot Rohde11Clinical Research Group “Significance of viral infections in chronic respiratory diseases of children and adults,” University Hospital Bergmannsheil, Department of Internal Medicine III–Pneumology, Allergology and Sleep Medicine, Bochum, Germany; 2Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, and Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, SwedenObjective: Human bocavirus (HBoV is a recently discovered parvovirus associated with acute respiratory tract infections in children. The objective of the present study was to determine the frequency and clinical relevance of HBoV infection in adult patients with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD.Methods: We retrospectively tested 212 COPD patients, 141 (66.5% with AE-COPD and 71 (33.5% with stable disease, of whom nasal lavage and induced sputum had been obtained for the presence of HBoV deoxyribonucleic acid (DNA. The specificity of positive polymerase chain reaction results was confirmed by sequencing.Results: Two hundred two of 212 patients for whom PCR results were available both for nasal lavage and induced sputum samples were eligible for data analysis. HBoV DNA was detected in three patients (1.5%. Of those, only one patient had AE-COPD. Thus, the frequency of HBoV infection demonstrated to be low in both AE-COPD (0.8% and stable COPD (2.9%. HBoV was found in two sputum and one nasal lavage sample in different patients, respectively. Sequencing revealed >99% sequence identity with the reference strain.Conclusion: HBoV detection was infrequent. Since we detected HBoV in both upper and lower respiratory tract specimens and in AE-COPD as well as stable disease, a major role of HBoV infection in adults with AE-COPD is unlikely

The American Gas Centrifuge Past, Present, and Future

Energy Technology Data Exchange (ETDEWEB)

Waters, Dean

2004-09-15

The art of gas centrifugation was born in 1935 at the University of Virginia when Dr. Jesse Beams demonstrated experimentally the separation of chlorine isotopes using an ultra-high speed centrifuge. Dr. Beam’s experiment initiated work that created a rich history of scientific and engineering accomplishment in the United States in the art of isotope separation and even large scale biological separation by centrifugation. The early history of the gas centrifuge development was captured in a lecture and documented by Dr. Jesse Beams in 1975. Much of Dr. Beams lecture material is used in this paper up to the year 1960. Following work by Dr. Gernot Zippe at the University of Virginia between 1958 and 1960, the US government embarked on a centrifuge development program that ultimately led to the start of construction of the Gas Centrifuge Enrichment Plant in Piketon Ohio in the late 1970’s. The government program was abandoned in 1985 after investing in the construction of two of six planned process buildings, a complete supply chain for process and centrifuge parts, and the successful manufacture and brief operation of an initial complement of production machines that would have met 15 percent of the planned capacity of the constructed process buildings. A declining market for enriched uranium, a glut of uranium enrichment capacity worldwide, and the promise of a new laser based separation process factored in the decision to stop the government program. By the late 1990’s it had become evident that gas centrifugation held the best promise to produce enriched uranium at low cost. In1999, the United States Enrichment Corporation undertook an initiative to revive the best of the American centrifuge technology that had been abandoned fourteen years earlier. This is an exciting story and one that when complete will enable the United States to maintain its domestic supply and to be highly competitive in the world market for this important energy commodity. (auth)

Energy efficiency. A constant challenge to science and practice. Proceedings. 2. ed.; Energieeffizienz. Eine stete Herausforderung an Wissenschaft und Praxis. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Wagner, Ulrich (ed.)

2011-07-01

Within the meeting ''Energy efficiency'' of the Research Center for Energy Economics (Munich, Federal Republic of Germany) from 12th to 13th May, 2011, at the Munich Residenz (Munich, Federal Republic of Germany) the following lectures were presented: (1) Innovation and research for an enhanced energy efficiency - New accents in the energy research politics of the Federal Government (Knut Kuebler); (2) Revolution of efficiency in the monastery St. Ottilien (Wolfgang Mauch); (3) From the maser plan to the local plan of energy utilization (Tobias Schmid); (4) The life cycle approach as a driver for innovative energy contracting (Alfred Gayer); (5) Energy efficiency networks (Anna Gruber); (6) Grid expansion for an enhanced utilization of renewable energies (Martin Fuchs); (7) Storage requirement in the electrical grid; (8) Scenarios for the development of the electromobility in Munich (Stephan Brunnert); (9) Li ion batteries for electrified automobiles - Demands and status (Peter Lamp); (10) Marketing of wind power (Serafin von Roon); (11) Demand side management in non-residential buildings (Johannes Jungwirth); (12) Energy future 2050 (Ulrich Wagner); (13) Decentral and renewable power generation (Ulli Arndt); (14) Electromobility - is that the future? (Markus Lienkamp); (14) Electric power - Reason or solution of the climate problem? (Harald Lesch).

Homecoming as a National Founding Myth: Jewish Identity and German Landscapes in Konrad Wolf’s I was Nineteen

Directory of Open Access Journals (Sweden)

Ofer Ashkenazi

2012-03-01

Full Text Available Konrad Wolf was one of the most enigmatic intellectuals of East Germany. The son of the Jewish Communist playwright Friedrich Wolf and the brother of Markus Wolf—the head of the GDR’s Foreign Intelligence Agency—Konrad Wolf was exiled in Moscow during the Nazi era and returned to Germany as a Red Army soldier by the end of World War Two. This article examines Wolf’s 1968 autobiographical film I was Nineteen (Ich war Neunzehn, which narrates the final days of World War II—and the initial formation of postwar reality—from the point of view of an exiled German volunteer in the Soviet Army. In analyzing Wolf’s portrayals of the German landscape, I argue that he used the audio-visual clichés of Heimat-symbolism in order to undermine the sense of a homogenous and apolitical community commonly associated with this concept. Thrown out of their original contexts, his displaced Heimat images negotiate a sense of a heterogeneous community, which assumes multi-layered identities and highlights the shared ideology rather than the shared origins of the members of the national community. Reading Wolf from this perspective places him within a tradition of innovative Jewish intellectuals who turned Jewish sensibilities into a major part of modern German mainstream culture.

Energy efficiency. A constant challenge to science and practice. Proceedings. 2. ed.; Energieeffizienz. Eine stete Herausforderung an Wissenschaft und Praxis. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Wagner, Ulrich [ed.

2011-07-01

Within the meeting ''Energy efficiency'' of the Research Center for Energy Economics (Munich, Federal Republic of Germany) from 12th to 13th May, 2011, at the Munich Residenz (Munich, Federal Republic of Germany) the following lectures were presented: (1) Innovation and research for an enhanced energy efficiency - New accents in the energy research politics of the Federal Government (Knut Kuebler); (2) Revolution of efficiency in the monastery St. Ottilien (Wolfgang Mauch); (3) From the maser plan to the local plan of energy utilization (Tobias Schmid); (4) The life cycle approach as a driver for innovative energy contracting (Alfred Gayer); (5) Energy efficiency networks (Anna Gruber); (6) Grid expansion for an enhanced utilization of renewable energies (Martin Fuchs); (7) Storage requirement in the electrical grid; (8) Scenarios for the development of the electromobility in Munich (Stephan Brunnert); (9) Li ion batteries for electrified automobiles - Demands and status (Peter Lamp); (10) Marketing of wind power (Serafin von Roon); (11) Demand side management in non-residential buildings (Johannes Jungwirth); (12) Energy future 2050 (Ulrich Wagner); (13) Decentral and renewable power generation (Ulli Arndt); (14) Electromobility - is that the future? (Markus Lienkamp); (14) Electric power - Reason or solution of the climate problem? (Harald Lesch).

gemcWeb: A Cloud Based Nuclear Physics Simulation Software

Science.gov (United States)

Markelon, Sam

2017-09-01

gemcWeb allows users to run nuclear physics simulations from the web. Being completely device agnostic, scientists can run simulations from anywhere with an Internet connection. Having a full user system, gemcWeb allows users to revisit and revise their projects, and share configurations and results with collaborators. gemcWeb is based on simulation software gemc, which is based on standard GEant4. gemcWeb requires no C++, gemc, or GEant4 knowledge. Using a simple but powerful GUI allows users to configure their project from geometries and configurations stored on the deployment server. Simulations are then run on the server, with results being posted to the user, and then securely stored. Python based and open-source, the main version of gemcWeb is hosted internally at Jefferson National Labratory and used by the CLAS12 and Electron-Ion Collider Project groups. However, as the software is open-source, and hosted as a GitHub repository, an instance can be deployed on the open web, or any institution's intra-net. An instance can be configured to host experiments specific to an institution, and the code base can be modified by any individual or group. Special thanks to: Maurizio Ungaro, PhD., creator of gemc; Markus Diefenthaler, PhD., advisor; and Kyungseon Joo, PhD., advisor.

Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease.

Science.gov (United States)

Simon, Matthew J; Iliff, Jeffrey J

2016-03-01

Cerebrospinal fluid (CSF) circulation and turnover provides a sink for the elimination of solutes from the brain interstitium, serving an important homeostatic role for the function of the central nervous system. Disruption of normal CSF circulation and turnover is believed to contribute to the development of many diseases, including neurodegenerative conditions such as Alzheimer's disease, ischemic and traumatic brain injury, and neuroinflammatory conditions such as multiple sclerosis. Recent insights into CSF biology suggesting that CSF and interstitial fluid exchange along a brain-wide network of perivascular spaces termed the 'glymphatic' system suggest that CSF circulation may interact intimately with glial and vascular function to regulate basic aspects of brain function. Dysfunction within this glial vascular network, which is a feature of the aging and injured brain, is a potentially critical link between brain injury, neuroinflammation and the development of chronic neurodegeneration. Ongoing research within this field may provide a powerful new framework for understanding the common links between neurodegenerative, neurovascular and neuroinflammatory disease, in addition to providing potentially novel therapeutic targets for these conditions. This article is part of a Special Issue entitled: Neuro Inflammation edited by Helga E. de Vries and Markus Schwaninger. Copyright © 2015 Elsevier B.V. All rights reserved.

Dosimetric accuracy of a treatment planning system for actively scanned proton beams and small target volumes: Monte Carlo and experimental validation

Science.gov (United States)

Magro, G.; Molinelli, S.; Mairani, A.; Mirandola, A.; Panizza, D.; Russo, S.; Ferrari, A.; Valvo, F.; Fossati, P.; Ciocca, M.

2015-09-01

This study was performed to evaluate the accuracy of a commercial treatment planning system (TPS), in optimising proton pencil beam dose distributions for small targets of different sizes (5-30 mm side) located at increasing depths in water. The TPS analytical algorithm was benchmarked against experimental data and the FLUKA Monte Carlo (MC) code, previously validated for the selected beam-line. We tested the Siemens syngo® TPS plan optimisation module for water cubes fixing the configurable parameters at clinical standards, with homogeneous target coverage to a 2 Gy (RBE) dose prescription as unique goal. Plans were delivered and the dose at each volume centre was measured in water with a calibrated PTW Advanced Markus® chamber. An EBT3® film was also positioned at the phantom entrance window for the acquisition of 2D dose maps. Discrepancies between TPS calculated and MC simulated values were mainly due to the different lateral spread modeling and resulted in being related to the field-to-spot size ratio. The accuracy of the TPS was proved to be clinically acceptable in all cases but very small and shallow volumes. In this contest, the use of MC to validate TPS results proved to be a reliable procedure for pre-treatment plan verification.

Dosimetric accuracy of a treatment planning system for actively scanned proton beams and small target volumes: Monte Carlo and experimental validation

International Nuclear Information System (INIS)

Magro, G; Molinelli, S; Mairani, A; Mirandola, A; Panizza, D; Russo, S; Valvo, F; Fossati, P; Ciocca, M; Ferrari, A

2015-01-01

This study was performed to evaluate the accuracy of a commercial treatment planning system (TPS), in optimising proton pencil beam dose distributions for small targets of different sizes (5–30 mm side) located at increasing depths in water. The TPS analytical algorithm was benchmarked against experimental data and the FLUKA Monte Carlo (MC) code, previously validated for the selected beam-line. We tested the Siemens syngo ® TPS plan optimisation module for water cubes fixing the configurable parameters at clinical standards, with homogeneous target coverage to a 2 Gy (RBE) dose prescription as unique goal. Plans were delivered and the dose at each volume centre was measured in water with a calibrated PTW Advanced Markus ® chamber. An EBT3 ® film was also positioned at the phantom entrance window for the acquisition of 2D dose maps. Discrepancies between TPS calculated and MC simulated values were mainly due to the different lateral spread modeling and resulted in being related to the field-to-spot size ratio. The accuracy of the TPS was proved to be clinically acceptable in all cases but very small and shallow volumes. In this contest, the use of MC to validate TPS results proved to be a reliable procedure for pre-treatment plan verification. (paper)

Estimating the impact of enterprise resource planning project management decisions on post-implementation maintenance costs: a case study using simulation modelling

Science.gov (United States)

Fryling, Meg

2010-11-01

Organisations often make implementation decisions with little consideration for the maintenance phase of an enterprise resource planning (ERP) system, resulting in significant recurring maintenance costs. Poor cost estimations are likely related to the lack of an appropriate framework for enterprise-wide pre-packaged software maintenance, which requires an ongoing relationship with the software vendor (Markus, M.L., Tanis, C., and Fenema, P.C., 2000. Multisite ERP implementation. CACM, 43 (4), 42-46). The end result is that critical project decisions are made with little empirical data, resulting in substantial long-term cost impacts. The product of this research is a formal dynamic simulation model that enables theory testing, scenario exploration and policy analysis. The simulation model ERPMAINT1 was developed by combining and extending existing frameworks in several research domains, and by incorporating quantitative and qualitative case study data. The ERPMAINT1 model evaluates tradeoffs between different ERP project management decisions and their impact on post-implementation total cost of ownership (TCO). Through model simulations a variety of dynamic insights were revealed that could assist ERP project managers. Major findings from the simulation show that upfront investments in mentoring and system exposure translate to long-term cost savings. The findings also indicate that in addition to customisations, add-ons have a significant impact on TCO.

PREFACE: PASREG 2003: International Workshop on Processing and Applications of Superconducting (RE)BCO Large Grain Materials

Science.gov (United States)

Murakami, Masato; Cardwell, David; Salama, Kamel; Krabbes, Gernot; Habisreuther, Tobias; Gawalek, Wolfgang

2005-02-01

Superconducting melt-textured bulk (RE)BCO large grain materials are one of the most promising materials for power applications of high temperature superconductivity at the liquid nitrogen temperature range. Industrial applications are expected in high-speed low-loss magnetic bearings for flywheel energy storage devices, high-dynamic high-torque electric reluctance motors, and MAGLEV transportation systems. The material has high magnetic field trapping capability and therefore a new class of high-field superconducting permanent magnets will soon appear. However, there is still the need to improve the magnetic and mechanical material properties, as well as to increase the single domain size. This special issue contains papers concerning these topics presented at the International Workshop on the Processing and Applications of Superconducting (RE)BCO Large Grain Materials. The workshop was held on the 30 June-2 July 2003 in Jena, Germany, and was organized by the Institut fuer Physikalische Hochtechnologie, Jena. It was the fourth in the series of PASREG workshops after Cambridge, UK (1997), Morioka, Japan (1999), and Seattle, USA (2001). Sixty two contributions were presented at the workshop, 38 oral presentations and 24 poster presentations. This special issue contains 42 papers. The editors are grateful for the support of many colleagues who reviewed the manuscripts to guarantee their high technical quality. The editors also wish to thank Doris Litzkendorf and Tobias Habisreuther from Institut fuer Physikalische Hochtechnologie, Jena, for their assistance with the organization and handling of the manuscripts. Many thanks to the workshop co-chairman Gernot Krabbes from Leibniz-Institut fuer Festkoerper und Werkstoffforschung, Dresden, for hosting the workshop participants in Dresden. Finally, all attendees wish to acknowledge the efforts of Wolfgang Gawalek, Tobias Habisreuther, Doris Litzkendorf and the Team of Department Magnetics from the Institut fuer

Establishment of a biophysical model to optimize endoscopic targeting of magnetic nanoparticles for cancer treatment

Directory of Open Access Journals (Sweden)

Roeth AA

2017-08-01

Full Text Available Anjali A Roeth,1,* Ioana Slabu,2,* Martin Baumann,2 Patrick H Alizai,1 Maximilian Schmeding,1 Gernot Guentherodt,3 Thomas Schmitz-Rode,2 Ulf P Neumann1 1Department of General, Visceral and Transplant Surgery, University Hospital RWTH Aachen, 2Institute of Applied Medical Engineering, Helmholtz-Institute Aachen, RWTH Aachen, Aachen, 3Institute of Physics A, RWTH Aachen University, Aachen, Germany *These authors contributed equally to this work Abstract: Superparamagnetic iron oxide nanoparticles (SPION may be used for local tumor treatment by coupling them to a drug and accumulating them locally with magnetic field traps, that is, a combination of permanent magnets and coils. Thereafter, an alternating magnetic field generates heat which may be used to release the thermosensitively bound drug and for hyperthermia. Until today, only superficial tumors can be treated with this method. Our aim was to transfer this method into an endoscopic setting to also reach the majority of tumors located inside the body. To find the ideal endoscopic magnetic field trap, which accumulates the most SPION, we first developed a biophysical model considering anatomical as well as physical conditions. Entities of choice were esophageal and prostate cancer. The magnetic susceptibilities of different porcine and rat tissues were measured with a superconducting quantum interference device. All tissues showed diamagnetic behavior. The evaluation of clinical data (computed tomography scan, endosonography, surgical reports, pathological evaluation of patients gave insight into the topographical relationship between the tumor and its surroundings. Both were used to establish the biophysical model of the tumors and their surroundings, closely mirroring the clinical situation, in which we could virtually design, place and evaluate different electromagnetic coil configurations to find optimized magnetic field traps for each tumor entity. By simulation, we could show that the

Monte Carlo simulation applied to radiosurgery narrow beams using MCNP-4C

International Nuclear Information System (INIS)

Chaves, A.; Lopes, M.C.; Oliveira, C.

2001-01-01

Dose measurements for the narrow photon beams used in radiosurgery are complicated by the lack of electron equilibrium which is a requirement namely for ionometric methods. To overcome this difficulty the use of different dosimetric supports is strongly recommended in order to appreciate the influence of each type of detector. Monte Carlo simulation is another kind of tool to assess the details of the energy deposition phenomena in such narrow photon beams. In this study output factors and depth dose calculated by the Monte Carlo MCNP-4C code are presented and compared with experimental data measured with a diode, a Markus chamber, a 0.125 cc thimble chamber and a Pinpoint chamber. Simulated energy spectra for narrow beams are also presented in order to compare them with the reference 10 cm x 10 cm beam field size and thus discuss the different contributions of the absorbed energy in water, in each case. A detailed analysis on the photon energy spectra showed a slight decrease on the photon mean energy that can be explained by the increased scattering inside the additional collimators. Calculated and measured depth doses curves are in good agreement for most of the collimators. For the two smallest collimators some differences have been pointed and explained according to the characteristics of the detectors (author)

Performance and Politics in the Public Sphere

Directory of Open Access Journals (Sweden)

Pia Wiegmink

2011-12-01

Full Text Available Pia Wiegmink’s timely examination of the transforming transnational spaces of protest in a globalizing and technologically mediated public sphere in “Performance and Politics in the Public Sphere” offers a well-researched review of contemporary theory surrounding ideas of the political (Chantal Mouffe, the public sphere (Jürgen Habermas, the transnational public sphere (Nancy Fraser, and the reterritorialized transnational public sphere (Markus Schroer as the basis for her analysis of how the performance of political action in public—virtual or physical—is transformed by the capacity of the local to be played on a global stage, thus turning the citizen-actor into a cosmopolitan, transnational force. Tracing examples from the Seattle protests against the World Trade Organization meetings in 1999 by the Global Justice Movement to the work of the Electronic Disturbance Theater, from the civil rights movement to the subject matter of her larger study, “The Church of Life After Shopping,” “Billionaires for Bush,” and “The Yes Men,” Wiegmink provides an important analysis of the “alternative aesthetics” of the counterpublics’ formation, dissent, and action in and against hegemony. This selection is taken from her monograph, Protest EnACTed: Activist Performance in the Contemporary United States, a strong, cultural studies–focused contribution to transnational American Studies.

Performance and Politics in the Public Sphere

Directory of Open Access Journals (Sweden)

Pia Wiegmink

2011-12-01

Full Text Available Pia Wiegmink’s timely examination of the transforming transnational spaces of protest in a globalizing and technologically mediated public sphere in “Performance and Politics in the Public Sphere” offers a well-researched review of contemporary theory surrounding ideas of the political (Chantal Mouffe, the public sphere (Jürgen Habermas, the transnational public sphere (Nancy Fraser, and the reterritorialized transnational public sphere (Markus Schroer as the basis for her analysis of how the performance of political action in public—virtual or physical—is transformed by the capacity of the local to be played on a global stage, thus turning the citizen-actor into a cosmopolitan, transnational force. Tracing examples from the Seattle protests against the World Trade Organization meetings in 1999 by the Global Justice Movement to the work of the Electronic Disturbance Theater, from the civil rights movement to the subject matter of her larger study, “The Church of Life After Shopping,” “Billionaires for Bush,” and “The Yes Men,” Wiegmink provides an important analysis of the “alternative aesthetics” of the counterpublics’ formation, dissent, and action in and against hegemony. This selection is taken from her monograph, Protest EnACTed: Activist Performance in the Contemporary United States, a strong, cultural studies–focused contribution to transnational American Studies.

Opfer des NS-Bücherraubes – 10 Fälle aus medizinischen Bibliotheken in Wien: Provenienzforschungsprojekt an der Universitätsbibliothek der Medizinischen Universität Wien / Victims of book expropriation during nazi regime – 10 examples from medical libraries in Vienna: provenance research project at the university library at the Medical University Vienna

Directory of Open Access Journals (Sweden)

Bauer, Bruno

2008-01-01

Full Text Available Since 2007 the university library at the Medical University Vienna runs a provenance research project. Books, stolen between 1938 and 1945, were acquired by at that time discrete libraries at institutions and clinics of the former medical faculty at Vienna University. A systematic survey of the now centralised book collection should bring to light these misgotten book acquisitions. Aim of the project is to document such cases and to restitute books to their lawful owners or their legal successors. Until Novemver 2008 about 80,000 volumes were scrutinised directly at the shelves by so-called autopsy. So far about 200 definitely stolen books and approximately 1800 suspicious books were dedected. This paper describes the initial position, method and hitherto existing results of the provenance research project. Ten cases of such book theft, recorded in the now centralised collection of the university library of the Medical University Vienna (former medical faculty, should depict victims of book expropiation during nazi regime. These cases include second-hand bookshops (Alois Fantl, Hans Peter Kraus, an university professor from the former medical faculty at Vienna University (Markus Hajek, general practitioners not associated with the former medical faculty (Adolf Kronfeld, Richard Löwi, private persons (Lily Fuchs, Raoul Fernand Jellinek-Mercedes and books from public and private libraries (Akademischer Verein jüdischer Mediziner, Bibliothek Sassenbach, Ortskrankenkasse Dresden.

Resenha: Como não escrever um artigo médico

Directory of Open Access Journals (Sweden)

Jacqueline Messias dos Santos

2018-04-01

Full Text Available O livro escrito por Markus K. Heinemann, Phd e especialista em cirurgia vascular, torácica e cardíaca, pela Universitatsmedizin Mains, na Alemanha, tem por objetivo apontar os erros mais comuns ao se escrever um artigo médico. Na sua experiência como editor-chefe da revista científica The Thoracic and Cardiovascular Surgeon, entrou em contato com diversos tipos de artigos com erros recorrentes e, a partir daí, surgiu a ideia para um guia passo a passo de como evitá-los, levando em consideração todos os pormenores que a escrita científica e acadêmica exige. Levando em consideração que, muitas vezes, a linguagem de um artigo científico é extremamente complexa e por vezes inacessível, o autor propõe escrever algo simples que seja de fácil acesso e entendimento para o leitor de modo que o leitor também possa escrever artigos médicos com linguagem clara e acessível. As falhas dos artigos, segundo o autor, são de ordens editoriais e repetidas cotidianamente, nesse sentido o manual contribui significativamente para o entendimento de todo o processo de elaboração de um artigo médico, desde a escrita à publicação.

A practical approach for electron monitor unit calculation

International Nuclear Information System (INIS)

Choi, David; Patyal, Baldev; Cho, Jongmin; Cheng, Ing Y; Nookala, Prashanth

2009-01-01

Electron monitor unit (MU) calculation requires measured beam data such as the relative output factor (ROF) of a cone, insert correction factor (ICF) and effective source-to-surface distance (ESD). Measuring the beam data to cover all possible clinical cases is not practical for a busy clinic because it takes tremendous time and labor. In this study, we propose a practical approach to reduce the number of data measurements without affecting accuracy. It is based on two findings of dosimetric properties of electron beams. One is that the output ratio of two inserts is independent of the cone used, and the other is that ESD is a function of field size but independent of cone and jaw opening. For the measurements to prove the findings, a parallel plate ion chamber (Markus, PTW 23343) with an electrometer (Cardinal Health 35040) was used. We measured the outputs to determine ROF, ICF and ESD of different energies (5-21 MeV). Measurements were made in a Plastic Water(TM) phantom or in water. Three linear accelerators were used: Siemens MD2 (S/N 2689), Siemens Primus (S/N 3305) and Varian Clinic 21-EX (S/N 1495). With these findings, the number of data set to be measured can be reduced to less than 20% of the data points. (note)

Teaching Library: Vermittlung von Informationskompetenz an medizinischen Bibliotheken

Directory of Open Access Journals (Sweden)

Bauer, Bruno

2014-08-01

Full Text Available [english] The focus of the current issue 1-2/2014 of GMS Medizin – Bibliothek – Information is on “Teaching Library: information literacy instruction at medical libraries”. The authors in this issue are Marina Betker & Annette Kustos (Literature research training in health sciences in a new academic library – straight through and strategic planning: the concept of the “hsg Bochum”, Simone Waldboth (Integration of e-learning in the lecture “Information Literacy” at the Provincial College for Health-Care Professions „Claudiana“, Michaele Adam & Jens Mittelbach (Shaping the Future at the SLUB Dresden with Information Literacy in the Research Cycle, Gregor Steinrisser (Sucessfully failing – Fiction and Friction of a teaching library in university and clinical daily routine, Melanie Kintzel & Norbert Sunderbrink (Information literacy classes at the Medical Library of the University Medical Center Hamburg-Eppendorf, Markus Schmiel (The teaching and learning concept of the Library of the Hannover Medical School, Jutta Matrisciano & Martina Semmler-Schmetz (Teaching Library – Realization of a concept with many facets at the Library for the Medical Faculty of Mannheim, Karin Cepicka („Teaching Library“ at the Library oft the Medical University Vienna, Helmut Dollfuß (Library user education for the new curriculum at the Medical University Vienna, Manuela Rohrmoser & Irene Schachl (The cooperations of teaching librarians at Vienna University Library und Claudia Hausberger & David Frank (Curriculum reform – a work report from the Library of the University of Veterinary Medicine Vienna.

A comparison of two photon planning algorithms for 8 MV and 25 MV X-ray beams in lung

International Nuclear Information System (INIS)

Kan, M.W.K.; Young, E.C.M.; Yu, P.K.N.

1995-01-01

The results of a comparison of two photon planning algorithms, the Clarkson Scatter Integration algorithm and the Equivalent Tissue-air Ratio algorithm are reported, using a simple lung phantom for 8 MV and 25 MV X-ray beams of field sizes 5 cm x 5 cm and 10 cm x 10 cm. Central axis depth-dose distributions were measured with a thimble chamber or a Markus parallel-plate chamber. Dose profile distributions were measured with TLD rods and films. Measured dose distributions were then compared to predicted dose distributions. Both algorithms overestimate the dose at mid-lung as they do not account for the effect of electronic disequilibrium. The Clarkson algorithm consistently shows less accurate results in comparison with the ETAR algorithm. There is additional error in the case of the Clarkson algorithm because of the assumption of a unit density medium in calculating scatter, which gives an overestimate in the effective scatter-air ratios in lung. For a 5 cm x 5 cm field, the error of dose prediction for 25 MV x-ray beam at mid-lung is 15.8 % and 12.8 % for Clarkson and ETAR algorithm respectively. At 8 MV the error is 9.3 % and 5.1 % respectively. In addition, both algorithms underestimate the penumbral width at mid-lung as they do not account for the penumbral flaring effect in low density medium. 25 refs., 2 tabs., 5 figs

Physical activity and self-esteem: testing direct and indirect relationships associated with psychological and physical mechanisms

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Zamani Sani SH

2016-10-01

Full Text Available Seyed Hojjat Zamani Sani,1 Zahra Fathirezaie,1 Serge Brand,2 Uwe Pühse,3 Edith Holsboer-Trachsler,2 Markus Gerber,3 Siavash Talepasand4 1Department of Motor Behavior, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran; 2Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders (ZASS, 3Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland; 4Department of Psychology and Educational Sciences, Semnan University, Semnan, Iran Abstract: In the present study, we investigated the relationship between physical activity (PA and self-esteem (SE, while introducing body mass index (BMI, perceived physical fitness (PPF, and body image (BI in adults (N =264, M =38.10 years. The findings indicated that PA was directly and indirectly associated with SE. BMI predicted SE neither directly nor indirectly, but was directly associated with PPF and both directly and indirectly with BI. Furthermore, PPF was directly related to BI and SE, and a direct association was found between BI and SE. The pattern of results suggests that among a sample of adults, PA is directly and indirectly associated with SE, PPF, and BI, but not with BMI. PA, PPF, and BI appear to play an important role in SE. Accordingly, regular PA should be promoted, in particular, among adults reporting lower SE. Keywords: physical activity, self-esteem, physical fitness, body image, adults

Thinking Beyond the Categories: On the Diasporisation of Gender Studies

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Stefanie Kron

2013-01-01

Full Text Available In diesem Beitrag wird das Potential des Konzepts „Diaspora“ für eine feministische Methodologie diskutiert. Die Überlegungen gehen von der Beobachtung aus, dass die Mehrheit der Geschlechter- und Intersektionalitätsforschung in Deutschland innerhalb eines nationalen Rahmens arbeitet. Entsprechend fehlt ihr das Bewusstsein von den globalen Verknüpfungen und der konstitutiven Bedeutung von Migration für die europäischen Gesellschaften seit den Zeiten von Kolonisation und Sklavenhandel. Es gibt deshalb innerhalb der Geschlechterforschung eine Tendenz, Differenzen zu essentialisieren, obwohl das erklärte Ziel die Analyse sozialer Ungleichheiten ist. Nach einem kursorischen Überblickt über die Konzepte, die Gesellschaft aus der Perspektive der Bewegung und Diasporisierung betrachten – wie Édouard Glissant’s ‚créolisation‘, Paul Gilroy’s ‚black Atlantic‘ ebenso wie Peter Linebaugh’s und Markus Rediker’s ‚red Atlantic‘ – werden in diesem Artikel drei feministische Ansätze aus den 1980er und 1990er Jahren wieder aufgegriffen, die Elemente von dem, was als diasporische feministische Methode bezeichnet werden kann, enthalten: Es handelt sich um Angela Davis’ analytische Methode der Perspektivität, Avtar Brahs Auffassung vom ‚diaspora space‘ und Gloria Anzaldúas ‚border thinking‘. Im letzten Abschnitt des Beitrags wird gezeigt, wie diese konzeptionellen Instrumente zu einem besseren Verständnis interdependenter und globalisierter sozialer Ungleichheiten beitragen, indem sie Gender- und Intersektionalitätsstudien um die Diaspora-Perspektive erweitern.

Conceptos y medición de la pobreza. La necesidad de ampliar la mirada

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Julio Boltvinik

2003-01-01

Full Text Available El artículo sostiene que, en el estudio de la pobreza, situarse desde el principio en el “eje del nivel de vida”, como lo hacen casi todos los autores, impide la adecuada identificación de los “elementos constitutivos” de este eje. Como opción se plantea ampliar la perspectiva, partir del “eje del florecimiento humano” (donde el ser humano se encuentra completo y “recortar” su contenido para arribar al del eje del nivel de vida. En el eje del florecimiento humano es donde puede desarrollarse la reflexión sobre las “necesidades y capacidades humanas” que, a su vez, debe fundamentarse en una discusión sistemática sobre la “esencia humana”. La identificación de los pobres es una operación de corte (la definición del umbral en el eje del nivel de vida, en el cual sólo se consideran los elementos económicos de las necesidades y capacidades humanas. Estos son los temas que se desarrollan en la primera parte de este ensayo, apoyándose, entre otros, en las ideas de Marx (tal como las ha interpretado Giörgy Markus y en las de Abraham Maslow, mientras en la segunda se presenta un esquema preliminar de los elementos determinantes del florecimiento humano.

Electron beam dosimetry. Calibration and use of plane parallel chambers following IAEA TRS-381 recommendations

International Nuclear Information System (INIS)

Lizuain, M.C.; Linero, D.; Picon, C.; Saldana, O.

2000-01-01

Using different plane parallel chamber types (NACP-02, PTW Roos and PTW Markus), and a cylindrical chamber NE-2571 as reference, the IAEA TRS-381 Code of Practice has been compared with the AAPM TG-39 dosimetry protocol for plane parallel chambers. N D,air pp was determined following the 60 Co in-phantom method and the electron beam method described in TRS-381, using water, PMMA and RMI-457 Solid Water phantoms. Differences were smaller than 0.5% between the two methods except for the PTW Roos chamber where the discrepancy was about 1.5%. The absorbed dose to water was determined according to the procedures and data of each protocol for electron beams between 4 and 18 MeV. Differences in absorbed dose were less than 1% when measurements were made in water, but a deviation of up to 2% was found between TRS-381 and TG-39 when PMMA phantoms were used. To validate the results obtained and to investigate differences between plastic and water phantoms in electron beam dosimetry, the scaling factor C pl and the fluence correction factor h m for PMMA and solid water RMI-457 were measured and compared to the data in TRS-381. Good agreement was found for C pl , but only when the plastics density were taken into account. The experimental values of h m have a large uncertainty but for PMMA a trend for h m being lower than in TRS-381 has been obtained. (author)

Psychiatric comorbidities in a young man with subacute myelopathy induced by abusive nitrous oxide consumption: a case report

Directory of Open Access Journals (Sweden)

Mancke F

2016-09-01

Full Text Available Falk Mancke,1,2,* Gintare Kaklauskaite,1,* Jennifer Kollmer,3 Markus Weiler1 1Department of Neurology, 2Department of General Psychiatry, Center for Psychosocial Medicine, 3Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany *These authors contributed equally to this work Abstract: Nitrous oxide (N2O, a long-standing anesthetic, is known for its recreational use, and its consumption is on the rise. Several case studies have reported neurological and psychiatric complications of N2O use. To date, however, there has not been a study using standardized diagnostic procedures to assess psychiatric comorbidities in a patient consuming N2O. Here, we report about a 35-year-old male with magnetic resonance imaging confirmed subacute myelopathy induced by N2O consumption, who suffered from comorbid cannabinoid and nicotine dependence as well as abuse of amphetamines, cocaine, lysergic acid diethylamide, and ketamine. Additionally, there was evidence of a preceding transient psychotic and depressive episode induced by synthetic cannabinoid abuse. In summary, this case raises awareness of an important mechanism of neural toxicity, with which physicians working in the field of ­substance-related disorders should be familiar. In fact, excluding N2O toxicity in patients with recognized substance-related disorders and new neurological deficits is compulsory, as untreated for months the damage to the nervous system is at risk of becoming irreversible. Keywords: addictive disorders, laughing gas, subacute combined degeneration, substance use disorder, vitamin B12 deficiency

Suppression and interpersonal harmony: a cross-cultural comparison between Chinese and European Americans.

Science.gov (United States)

Wei, Meifen; Su, Jenny C; Carrera, Stephanie; Lin, Shu-Ping; Yi, Fei

2013-10-01

Based on Markus and Kitayama's (1991) theory, this study was conducted to examine whether the association between emotional suppression and interpersonal harmony would be moderated by cultural group (i.e., Chinese and European Americans) and an Asian cultural value (i.e., emotional self-control). A total of 451 college students (205 Chinese and 246 European Americans) participated in this study. As expected, results indicated that the association between emotional suppression and interpersonal harmony was significantly positive for Chinese but not significant for European Americans. Similarly, when emotional self-control was examined as a moderator, the results still confirmed our hypotheses. That is, the association between emotional suppression and interpersonal harmony was significantly positive for those with stronger endorsement of emotional self-control but not for those with weaker endorsement of emotional self-control. Furthermore, we examined whether the above results could be replicated when forbearance (a construct similar to suppression) and distress disclosure (a construct opposite to suppression) were examined. The results showed the same pattern for forbearance and distress disclosure when cultural group or emotional self-control served as the moderator. The convergence of findings increased the robustness of our results. Finally, our data suggest that individuals from Eastern, interdependent cultures (e.g., Chinese) tend to value emotional suppression to preserve interpersonal harmony; individuals from Western, independent cultures may or may not necessarily suppress their emotions for this purpose. A comprehensive understanding of the different meanings of a specific strategy (i.e., emotional suppression) in different cultural contexts is important to promote effective cross-cultural counseling.

Silicon diodes as an alternative to diamond detectors for depth dose curves and profile measurements of photon and electron radiation

International Nuclear Information System (INIS)

Scherf, Christian; Moog, Jussi; Licher, Joerg; Kara, Eugen; Roedel, Claus; Ramm, Ulla; Peter, Christiane; Zink, Klemens

2009-01-01

Background: Depth dose curves and lateral dose profiles should correspond to relative dose to water in any measured point, what can be more or less satisfied with different detectors. Diamond as detector material has similar dosimetric properties like water. Silicon diodes and ionization chambers are also commonly used to acquire dose profiles. Material and Methods: The authors compared dose profiles measured in an MP3 water phantom with a diamond detector 60003, unshielded and shielded silicon diodes 60008 and 60012 and a 0.125-cm 3 thimble chamber 233642 (PTW, Freiburg, Germany) for 6- and 25-MV photons. Electron beams of 6, 12 and 18 MeV were investigated with the diamond detector, the unshielded diode and a Markus chamber 23343. Results: The unshielded diode revealed relative dose differences at the water surface below +10% for 6-MV and +4% for 25-MV photons compared to the diamond data. These values decreased to less than 1% within the first millimeters of water depth. The shielded diode was only required to obtain correct data of the fall-off zones for photon beams larger than 10 x 10 cm 2 because of important contributions of low-energy scattered photons. For electron radiation the largest relative dose difference of -2% was observed with the unshielded silicon diode for 6 MeV within the build-up zone. Spatial resolutions were always best with the small voluminous silicon diodes. Conclusion: Relative dose profiles obtained with the two silicon diodes have the same degree of accuracy as with the diamond detector. (orig.)

The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

International Nuclear Information System (INIS)

Cirrone, G.A.P.; Cuttone, G.; Di Rosa, F.; Raffaele, L.; Russo, G.; Guatelli, S.; Pia, M.G.

2006-01-01

At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility

The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

Science.gov (United States)

Cirrone, G. A. P.; Cuttone, G.; Di Rosa, F.; Raffaele, L.; Russo, G.; Guatelli, S.; Pia, M. G.

2006-01-01

At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility.

The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

Energy Technology Data Exchange (ETDEWEB)

Cirrone, G.A.P. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Cuttone, G. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Di Rosa, F. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Raffaele, L. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Russo, G. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Guatelli, S. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Via Dodecaneso 33, Genova (Italy); Pia, M.G. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Via Dodecaneso 33, Genova (Italy)

2006-01-15

At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility.

Silicon diodes as an alternative to diamond detectors for depth dose curves and profile measurements of photon and electron radiation.

Science.gov (United States)

Scherf, Christian; Peter, Christiane; Moog, Jussi; Licher, Jörg; Kara, Eugen; Zink, Klemens; Rödel, Claus; Ramm, Ulla

2009-08-01

Depth dose curves and lateral dose profiles should correspond to relative dose to water in any measured point, what can be more or less satisfied with different detectors. Diamond as detector material has similar dosimetric properties like water. Silicon diodes and ionization chambers are also commonly used to acquire dose profiles. The authors compared dose profiles measured in an MP3 water phantom with a diamond detector 60003, unshielded and shielded silicon diodes 60008 and 60012 and a 0.125-cm(3) thimble chamber 233642 (PTW, Freiburg, Germany) for 6- and 25-MV photons. Electron beams of 6, 12 and 18 MeV were investigated with the diamond detector, the unshielded diode and a Markus chamber 23343. The unshielded diode revealed relative dose differences at the water surface below +10% for 6-MV and +4% for 25-MV photons compared to the diamond data. These values decreased to less than 1% within the first millimeters of water depth. The shielded diode was only required to obtain correct data of the fall-off zones for photon beams larger than 10 x 10 cm(2) because of important contributions of low-energy scattered photons. For electron radiation the largest relative dose difference of -2% was observed with the unshielded silicon diode for 6 MeV within the build-up zone. Spatial resolutions were always best with the small voluminous silicon diodes. Relative dose profiles obtained with the two silicon diodes have the same degree of accuracy as with the diamond detector.

Bibliotheken im Fluss

Directory of Open Access Journals (Sweden)

Bauer, Bruno

2015-12-01

Full Text Available The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are Bruno Bauer (Research data – a new field of activity (also for libraries, Markus Fischer (Search filter for local holdings in bibnet.org, Ursula Georgy (Strategic marketing: Benefit positioning strategy of libraries as a content provider in competition, Mareike Grisse (Reading and understanding licensing agreements for electronic resources, Regine Küfner Lein (Access to medical full texts and databases in Norway by national licensing, Annette Kustos (Collection management and service concept at the academic library of the Hochschule für Gesundheit, Oliver Weiner (Medical documents in university repositories, Sabine Buroh (Impressions from the EAHIL Workshop, Edinburgh, 10–12 June 2015, Mareike Grisse (Supra-regional availability of licensed electronic content – ZB MEDs’ new models, Jana Pössel (LIVIVO: The new ZB MED search portal for life sciences, Jasmin Schmitz (Offering advice on open access publishing in libraries, Fabian Gail (Product and innovation management ZB MED and Dagmar Härter (Medical libraries: libraries in progress – annual meeting 2015 of the German MLA, September 7 to 9 at Basel, Switzerland. Furthermore this focus issue features articles from Eike Hentschel (Pioneer projects in medical libraries 2015: Introduction of the winners and Iris Reimann (German MLA News; Pioneer projects in medical libraries 2016 – Announcement.

Poster - 19: Investigation of Electron Reference Dosimetry Based on Optimal Chamber Shift

Energy Technology Data Exchange (ETDEWEB)

Zhan, Lixin; Jiang, Runqing; Liu, Baochang; Osei, Ernest [Grand River Regional Cancer Centre (Canada)

2016-08-15

An addendum/revision to AAPM TG-51 electron reference dosimetry is highly expected to meet the clinical requirement with the increasing usage of new ion chambers not covered in TG-51. A recent study, Med. Phys. 41, 111701, proposed a new fitting equation for the beam quality conversion factor k’{sub Q} to a wide spectrum of chambers. In the study, an optimal Effective Point of Measurement (EPOM) from Monte Carlo calculations was recommended and the fitting parameters to k’{sub Q} was based on it. We investigated the absolute dose obtained based on the optimal EPOM method and the original TG-51 method with k’{sub R50} determined differently. The results showed that using the Markus curve is a better choice than the well-guarded chamber fitting for an IBA PPC-05 parallel plate chamber if we need to strictly follow the AAPM TG-51 protocol. We also examined the usage of the new fitting equation with measurement performed at the physical EPOM, instead of the optimal EPOM. The former is more readily determined and more practical in clinics. Our study indicated that the k’{sub Q} fitting based on the optimal EPOM can be used to measurement at the physical EPOM with no significant clinical impact. The inclusion of Farmer chamber gradient correction P{sub gr} in k’{sub Q}, as in the mentioned study, asks for the precise positioning of chamber center at dref. It is not recommended in clinics to avoid over-correction for low electron energies, especially for an institute having matching Linacs implemented.

Evaluation of w values for carbon beams in air, using a graphite calorimeter.

Science.gov (United States)

Sakama, Makoto; Kanai, Tatsuaki; Fukumura, Akifumi; Abe, Kyoko

2009-03-07

Despite recent progress in carbon therapy, accurate values for physical data such as the w value in air or stopping power ratios for ionization chamber dosimetry have not been obtained. The absorbed dose to graphite obtained with the graphite calorimeter was compared with that obtained using the ionization chambers following the IAEA protocol in order to evaluate the w values in air for mono-energetic carbon beams of 135, 290, 400 and 430 MeV/n. Two cylindrical chambers (PTW type 30001 and PTW type 30011, Farmer) and two plane-parallel chambers (PTW type 23343, Markus and PTW type 34001, Roos) calibrated by the absorbed dose to graphite and exposure to the (60)Co photon beam were used. The comparisons to our calorimeter measurements revealed that, using the ionization chambers, the absorbed dose to graphite comes out low by 2-6% in this experimental energy range and with these chamber types and calibration methods. In the therapeutic energy range, the w values in air for carbon beams indicated a slight energy dependence; we, however, assumed these values to be constant for practical use because of the large uncertainty and unknown perturbation factors of the ionization chambers. The w values in air of the carbon beams were evaluated to be 35.72 J C(-1) +/- 1.5% in the energy range used in this study. This value is 3.5% larger than that recommended by the IAEA TRS 398 for heavy-ion beams. Using this evaluated result, the absorbed dose to water in the carbon beams would be increased by the same amount.

High-precision R-branch transition frequencies in the ν2 fundamental band of H 3+ %A Perry, Adam J.; Hodges, James N.; Markus, Charles R.; Kocheril, G. Stephen; McCall, Benjamin J.

Science.gov (United States)

Perry, Adam J.; Hodges, James N.; Markus, Charles R.; Kocheril, G. Stephen; McCall, Benjamin J.

2015-11-01

The H3+ molecular ion has served as a long-standing benchmark for state-of-the-art ab initio calculations of molecular potentials and variational calculations of rovibrational energy levels. However, the accuracy of such calculations would not have been confirmed if not for the wealth of spectroscopic data that has been made available for this molecule. Recently, a new high-precision ion spectroscopy technique was demonstrated by Hodges et al., which led to the first highly accurate and precise (∼MHz) H3+ transition frequencies. As an extension of this work, we present ten additional R-branch transitions measured to similar precision as a next step toward the ultimate goal of producing a comprehensive high-precision survey of this molecule, from which rovibrational energy levels can be calculated.

The role of family configuration in early childhood intellectual development in the context of an extended family system in Pakistan

Directory of Open Access Journals (Sweden)

Avan B

2007-01-01

Full Text Available Context: The confluence theory of intelligence by Zajonc and Markus emphasizes that individual intellectual difference of children manifests itself in the context of family configuration. Instead of assuming its generalizability, careful scientific work is required before applying the model to South Asian cultures where, predominantly, an extended family type exists. Aims: To assess the role of extended family configuration on the child′s intellectual development in a South Asian setting. Settings and Design: A cross-sectional study was conducted on 4-5-year-old preschool children residing in Karachi, Pakistan. Materials and Methods: Three hundred and forty-two child and mother dyads were assessed through a validated cognitive psychometric tool and through a structured questionnaire. Children who were registered at the main Mother and Child Health Centres (MCH of the Aga Khan Health Services, Pakistan (AKHSP Karachi and who were born between July 1st 1993-June 30th 1994 with traceable birth records at the maternity homes, were considered for this study. Statistical Analysis: Multivariate linear regression models were used to identify the individual effect of family configuration on the intellectual scores. Results: Family configuration variables such as number of co-residents ( P < 0.05 and the number of siblings ( P < 0.01 in the house were significantly correlated with the psychometric score. Even after controlling for gender, socio-economic status, birth order and birth intervals, significant differentials were observed in favor of an extended family system on a child′s intellectual development. Conclusion: The findings suggest the positive role of co-residents of an extended family environment on the intellectual development in early childhood.

The Bland-Altman analysis: Does it have a role in assessing radiation dosimeter performance relative to an established standard?

International Nuclear Information System (INIS)

Hill, R.F.; Tofts, P.S.; Baldock, C.

2010-01-01

Bland-Altman analysis is used to compare two different methods of measurement and to determine whether a new method of measurement may replace an existing accepted 'gold standard' method. In this work, Bland-Altman analysis has been applied to radiation dosimetry to compare the PTW Markus and Roos parallel plate ionisation chambers and a PTW PinPoint chamber against a Farmer type ionisation chamber which is accepted as the gold standard for radiation dosimetry in the clinic. Depth doses for low energy x-rays beams with energies of 50, 75 and 100 kVp were measured using each of the ionisation chambers. Depth doses were also calculated by interpolation of the data in the British Journal of Radiology (BJR) Report 25. From the Bland-Altman analysis, the mean dose difference between the two parallel plate chambers and the Farmer chambers was 1% over the range of depths measured. The PinPoint chamber gave significant dose differences compared to the Farmer chamber. There were also differences of up to 12% between the BJR Report 25 depth doses and the measured data. For the Bland-Altman plots, the lines representing the limits of agreement were selected to be a particular percentage agreement e.g. 1 or 2%, instead of being based on the standard deviation (σ) of the differences. The Bland-Altman statistical analysis is a powerful tool for making comparisons of ionisation chambers with an ionisation chamber that has been accepted as a 'gold standard'. Therefore we conclude that Bland-Altman analysis does have a role in assessing radiation dosimeter performance relative to an established standard.

Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom

Directory of Open Access Journals (Sweden)

Braeken DCW

2017-08-01

Full Text Available Dionne CW Braeken,1–3 Gernot GU Rohde,2 Frits ME Franssen,1,2 Johanna HM Driessen,3–5 Tjeerd P van Staa,3,6 Patrick C Souverein,3 Emiel FM Wouters,1,2 Frank de Vries3,4,7 1Department of Research and Education, CIRO, Horn, 2Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+, Maastricht, 3Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht, 4Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Centre (MUMC+, Maastricht, 5Department of Epidemiology, Care and Public Health Research Institute (CAPHRI, Maastricht, the Netherlands; 6Department of Health eResearch, University of Manchester, Manchester, 7MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK Background: Smoking increases the risk of community-acquired pneumonia (CAP and is associated with the development of COPD. Until now, it is unclear whether CAP in COPD is due to smoking-related effects, or due to COPD pathophysiology itself. Objective: To evaluate the association between COPD and CAP by smoking status. Methods: In total, 62,621 COPD and 191,654 control subjects, matched by year of birth, gender and primary care practice, were extracted from the Clinical Practice Research Datalink (2005–2014. Incidence rates (IRs were estimated by dividing the total number of CAP cases by the cumulative person-time at risk. Time-varying Cox proportional hazard models were used to estimate the hazard ratios (HRs for CAP in COPD patients versus controls. HRs of CAP by smoking status were calculated by stratified analyses in COPD patients versus controls and within both subgroups with never smoking as reference. Results: IRs of CAP in COPD patients (32.00/1,000 person-years and controls (6.75/1,000 person-years increased with age and female gender. The risk of CAP in COPD patients was higher than in controls (HR 4.51, 95% CI: 4.27–4.77. Current smoking

Un point de vue néoréaliste en épistémologie du journalisme

Directory of Open Access Journals (Sweden)

Gilles Gauthier

2017-01-01

Full Text Available Il peut y avoir un certain intérêt à traiter de la nature du journalisme non pas pour en circonscrire les limites, mais afin de mettre au jour les présuppositions qui président à sa pratique. C’est une proposition en ce sens qui est ici formulée. Le point de vue épistémologique qui est développé dans le texte est librement inspiré du réalisme naturaliste de John Searle et du « nouveau réalisme » de Maurizio Ferraris et Markus Gabriel. Il se décline en trois principes : un principe de réalité, un principe de vérité et un principe d’objectivité. Tels qu’ils sont ici caractérisés, ces trois principes sont ordonnés séquentiellement : du principe de réalité découle le principe de vérité duquel est dérivé le principe d’objectivité. Le principe de réalité pose que le journalisme porte sur un matériau préexistant qui lui donc indépendant : des faits existent que le journalisme prend pour objet. Ces faits sont pour la plupart ceux de la réalité sociale. Ils sont construits, mais pas par le journalisme. Suivant le principe de vérité, le journalisme fournit de la réalité dont il traite une représentation exacte. Il ne s’agit pas, en le reconnaissant, de défendre une thèse positiviste qui soutiendrait qu’il y a isomorphisme entre la réalité représentée et la représentation qu’en fournit le journalisme, mais de marquer que la visée du journalisme est de rendre compte de ce qui est effectivement le cas. Finalement, le principe d’objectivité spécifie que la quête de vérité en journalisme a pour méthode la production d’énoncés vérifonctionnels. Tel qu’ainsi entendu, le principe d’objectivité est tout à fait compatible avec l’idée de relativité conceptuelle et donc aussi avec la nature aspectuelle du journalisme. A worthwhile topic of study would be to examine the nature of journalism; not to circumscribe its boundaries, but to expose the presuppositions that govern its

Attachment Style and Internet Addiction: An Online Survey.

Science.gov (United States)

Eichenberg, Christiane; Schott, Markus; Decker, Oliver; Sindelar, Brigitte

2017-05-17

One of the clinically relevant problems of Internet use is the phenomenon of Internet addiction. Considering the fact that there is ample evidence for the relationship between attachment style and substance abuse, it stands to reason that attachment theory can also make an important contribution to the understanding of the pathogenesis of Internet addiction. The aim of this study was to examine people's tendency toward pathological Internet usage in relation to their attachment style. An online survey was conducted. Sociodemographic data, attachment style (Bielefeld questionnaire partnership expectations), symptoms of Internet addiction (scale for online addiction for adults), used Web-based services, and online relationship motives (Cyber Relationship Motive Scale, CRMS-D) were assessed. In order to confirm the findings, a study using the Rorschach test was also conducted. In total, 245 subjects were recruited. Participants with insecure attachment style showed a higher tendency to pathological Internet usage compared with securely attached participants. An ambivalent attachment style was particularly associated with pathological Internet usage. Escapist and social-compensatory motives played an important role for insecurely attached subjects. However, there were no significant effects with respect to Web-based services and apps used. Results of the analysis of the Rorschach protocol with 16 subjects corroborated these results. Users with pathological Internet use frequently showed signs of infantile relationship structures in the context of social groups. This refers to the results of the Web-based survey, in which interpersonal relationships were the result of an insecure attachment style. Pathological Internet use was a function of insecure attachment and limited interpersonal relationships. ©Christiane Eichenberg, Markus Schott, Oliver Decker, Brigitte Sindelar. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 17.05.2017.

Characterization of a MOSkin detector for in vivo skin dose measurements during interventional radiology procedures

Energy Technology Data Exchange (ETDEWEB)

Safari, M. J.; Wong, J. H. D.; Ng, K. H., E-mail: ngkh@um.edu.my [Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia and University of Malaya Research Imaging Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603 (Malaysia); Jong, W. L. [Clinical Oncology Unit, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603 (Malaysia); Cutajar, D. L.; Rosenfeld, A. B. [Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522 (Australia)

2015-05-15

Purpose: The MOSkin is a MOSFET detector designed especially for skin dose measurements. This detector has been characterized for various factors affecting its response for megavoltage photon beams and has been used for patient dose measurements during radiotherapy procedures. However, the characteristics of this detector in kilovoltage photon beams and low dose ranges have not been studied. The purpose of this study was to characterize the MOSkin detector to determine its suitability for in vivo entrance skin dose measurements during interventional radiology procedures. Methods: The calibration and reproducibility of the MOSkin detector and its dependency on different radiation beam qualities were carried out using RQR standard radiation qualities in free-in-air geometry. Studies of the other characterization parameters, such as the dose linearity and dependency on exposure angle, field size, frame rate, depth-dose, and source-to-surface distance (SSD), were carried out using a solid water phantom under a clinical x-ray unit. Results: The MOSkin detector showed good reproducibility (94%) and dose linearity (99%) for the dose range of 2 to 213 cGy. The sensitivity did not significantly change with the variation of SSD (±1%), field size (±1%), frame rate (±3%), or beam energy (±5%). The detector angular dependence was within ±5% over 360° and the dose recorded by the MOSkin detector in different depths of a solid water phantom was in good agreement with the Markus parallel plate ionization chamber to within ±3%. Conclusions: The MOSkin detector proved to be reliable when exposed to different field sizes, SSDs, depths in solid water, dose rates, frame rates, and radiation incident angles within a clinical x-ray beam. The MOSkin detector with water equivalent depth equal to 0.07 mm is a suitable detector for in vivo skin dosimetry during interventional radiology procedures.

Erratum: Erratum to: The Quadrennial Ozone Symposium 2016

Science.gov (United States)

Godin-Beekmann, Sophie; Petropavlovskikh, Irina; Reis, Stefan; Newman, Paul; Steinbrecht, Wolfgang; Rex, Markus; Santee, Michelle L.; Eckman, Richard S.; Zheng, Xiangdong; Tully, Matthew B.; Stevenson, David S.; Young, Paul; Pyle, John; Weber, Mark; Tamminen, Johanna; Mills, Gina; Bais, Alkiviadis F.; Heaviside, Clare; Zerefos, Christos

2018-03-01

The Quadrennial Ozone Symposium 2016 Sophie GODIN-BEEKMANN*1, Irina PETROPAVLOVSKIKH2, Stefan REIS3,20, Paul NEWMAN4, Wolfgang STEINBRECHT5, Markus REX6, Michelle L. SANTEE7, Richard S. ECKMAN8, Xiangdong ZHENG9, Matthew B. TULLY10, David S. STEVENSON11, Paul YOUNG12, John PYLE13, Mark WEBER14, Johanna TAMMINEN15, Gina MILLS16, Alkiviadis F. BAIS17, Clare HEAVISIDE18, and Christos ZEREFOS19 1 Observatoire de Versailles Saint-Quentin en Yvelines, Université de Versailles Saint-Quentin-en-Yvelines, CNRS, 78280 Guyancourt, France 2 CIRES, University of Colorado, Boulder, CO 80309, USA 3 NERC Centre for Ecology & Hydrology, Edinburgh EH26 0QB, UK 4 Goddard Space Flight Center, NASA, Greenbelt, MD 20771, USA 5 Hohenpeissenberg Meteorological Observatory, Deutscher Wetterdienst, 82383 Hohenpeissenberg, Germany 6 Alfred Wegener Institute, 14401 Potsdam, Germany 7 Jet Propulsion Laboratory, California Institute of Technology, CA 91109, USA 8 NASA Headquarters, Earth Science Division, Washington, DC, USA 9 Chinese Academy of Meteorological Sciences, Beijing, 100081, China 10 Bureau of Meteorology, Melbourne, Victoria 3001, Australia 11 University of Edinburgh, School of GeoSciences, Edinburgh EH9 3FE, UK 12 Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ, UK 13 University of Cambridge, Department of Chemistry, Cambridge CB2 1EW, UK 14 University of Bremen, Institute of Environmental Physics, 28359 Bremen, Germany 15 Finnish Meteorological Institute, Earth Observation, FI-00101 Helsinki, Finland 16 NERC Centre for Ecology and Hydrology, Bangor, Gwynedd LL57 2UW, Wales, UK 17 Aristotle University of Thessaloniki, Thessaloniki, Greece 18 Public Health England, Centre for Radiation, Chemical and Environmental Hazards, London, UK 19 Research Center for Atmospheric Physics & Climatology, Academy of Athens, Athens 10680, Greece 20 University of Exeter Medical School, Truro TR1 3HD, UK

Atlas of PET/MR imaging in oncology

International Nuclear Information System (INIS)

Ratib, Osman; Schwaiger, Markus; Beyer, Thomas

2013-01-01

Numerous illustrated clinical cases in different oncology domains. Includes digital interactive software matching the cases in the book. Interactive version based on the latest web standard, HTML5, ensuring the widest compatibility. Edited by three international opinion leaders/imaging experts in the field. This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments. The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images. The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.

Book Reviews | Reseñas

Directory of Open Access Journals (Sweden)

Book Review Editor, Barbara Hogenboom

2013-10-01

Full Text Available Violent Democracies in Latin America, edited by Enrique Desmond Arias and Daniel M. Goldstein; reviewed by Rivke Jaffe, p. 124Violence, Coercion, and State-Making in Twentieth Century Mexico. The Other Half of the Centaur, edited by Wil Pansters; reviewed by Markus-Michael Müller, p. 126Police Reform in Mexico. Informal Politics and the Challenge of Institutional Change, by Daniel M. Sabet; reviewed by Wil G. Pansters, p. 128Bribes, Bullets and Intimidation: Drug Trafficking and the Law in Central America, by Julie Marie Bunck and Michael Ross Fowler; reviewed by Sonja Wolf, p. 132Latin American Urban Development into the 21st Century: Towards a Renewed Perspective on the City, edited by Dennis Rodgers, Jo Beall and Ravi Kanbur; reviewed by Christien Klaufus, p. 133Latin America’s Turbulent Transitions: The Future of Twenty-First Century Socialism, by Roger Burbach, Michael Fox and Federico Fuentes; reviewed by Barry Cannon, p. 136Cuba and Its Neighbours: Democracy in Motion, by Arnold August; reviewed by Antonio Carmona Báez, p. 138Bolivia: Processes of Change, by John Crabtree and Ann Chaplin; reviewed by Gonzalo Rojas-Ortuste, p. 140The Rise of Ethnic Politics in Latin America, by Raúl L. Madrid; reviewed by Ton Salman, 142Intimate Indigeneities. Race, Sex, and History in the Small Spaces of Andean Life, by Andrew Canessa; reviewed by Annelou Ypeij, p. 145¡Américas Unidas! Nelson A. Rockefeller’s Office of Inter-American Affairs (1940-1946, edited by Gisela Cramer and Ursula Prutsch; reviewed by Darlene J. Sadlier, p. 146How a Revolutionary Art became Official Culture: Murals, Museums, and the Mexican State, by Mary Coffey; reviewed by Paula López Caballero, p. 148Sugar, Slavery, Christianity and the Making of Race, by Mark Edelman Boren; reviewed by Gert Oostindie, p. 150

Atlas of PET/MR imaging in oncology

Energy Technology Data Exchange (ETDEWEB)

Ratib, Osman [University Hospital of Geneva (Switzerland). Nuclear Medicine Division; Schwaiger, Markus [Technische Univ. Muenchen (Germany). Nuklearmedizinische Klinik und Poliklinik; Beyer, Thomas (eds.) [General Hospital Vienna (Austria). Center for Medical Physics and Biomedical Engineering

2013-08-01

Numerous illustrated clinical cases in different oncology domains. Includes digital interactive software matching the cases in the book. Interactive version based on the latest web standard, HTML5, ensuring the widest compatibility. Edited by three international opinion leaders/imaging experts in the field. This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments. The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images. The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.

TH-C-19A-09: Quantification of Transmission and Backscatter Factors as a function of Distance to Inhomogeneity Interface for Three Types of Surgical Implant Plates

Energy Technology Data Exchange (ETDEWEB)

Wilson, D; Mills, M; Wang, B [University of Louisville, Louisville, KY (United States)

2014-06-15

Purpose: Carbon fiber materials have been increasingly used clinically, mainly in orthopedics, as an alternative to metallic implants because of their minimal artifacts on CT and MRI images. This study characterizes the transmission and backscatter property of carbon fiber plates (CarboFix Orthopedics, Herzeliya, Israel) with measurements for radiation therapy applications, and compares them to traditional Stainless Steel (SS) and Titanium (Ti) metal materials. Methods: For the transmission measurements, 1-mm-thick test plate was placed upstream from a plane parallel Markus chamber, separated by various thicknesses of polystyrene plates in 0.5 cm increments between 0 and 5 cm. With this setup, we quantified the radiation transmission as a function of distance to the inhomogeneity interface. The LINAC source to detector distance was maintained at 100 cm and 200 MU was delivered for each measurement. Two 3-cm solid water phantoms were placed at the top and bottom to provide build up. All the measurements were performed for 6 MV and 18 MV photons. The backscatter measurements had the identical setup, except that the test plate was downstream of the chamber from radiation. Results: The carbon fiber plates did not introduce any measureable inhomogeneity effect on the transmission and backscatter factor because of its low atomic number. In contrast, traditional metal implant materials caused up to 15% dose difference at upstream and 25% backscatter at downstream from radiation. Such differences decrease as the distance to the inhomogeneity interface increases and become unmeasurable at distance of 3 cm and 1 cm for upstream and downstream, respectively. Conclusion: A new type of carbon fiber implant plate was evaluated and found to have minimal inhomogeneity effect in MV radiation beams. Patients would benefit from a carbon based implant over metal for radiation therapy due to their minimal backscatter and imaging artifacts.

Short cognitive behavioral therapy and cognitive training for adults with ADHD – a randomized controlled pilot study

Directory of Open Access Journals (Sweden)

Maarit Virta

2010-07-01

Full Text Available Maarit Virta1,2, Anita Salakari1, Mervi Antila1, Esa Chydenius1, Markku Partinen1, Markus Kaski1, Risto Vataja3, Hely Kalska2, Matti Iivanainen11Rinnekoti Research Centre, Espoo, Finland; 2Department of Psychology, University of Helsinki, Finland; 3Kellokoski Hospital, Kellokoski, FinlandAbstract: In clinical practice, a growing need exists for effective non-pharmacological ­treatments of adult attention-deficit/hyperactivity disorder (ADHD. Here, we present the results of a pilot study of 10 adults with ADHD participating in short-term individual ­cognitive-behavioral therapy (CBT, 9 adults participating in cognitive training (CT, and 10 controls. Self-report ­questionnaires, independent evaluations, and computerized neurocognitive testing were ­collected before and after the treatments to evaluate change. There were distinctive pre-hypotheses regarding the treatments, and therefore the statistical comparisons were conducted in pairs: CBT vs control, CT vs control, and CBT vs CT. In a combined ADHD symptom score based on self-reports, 6 participants in CBT, 2 in CT and 2 controls improved. Using independent evaluations, improvement was found in 7 of the CBT participants, 2 of CT ­participants and 3 controls. There was no treatment-related improvement in cognitive performance. Thus, in the CBT group, some encouraging improvement was seen, although not as clearly as in ­previous research with longer interventions. In the CT group, there was improvement in the trained tasks but no generalization of the improvement to the tasks of the neurocognitive testing, the ­self-report questionnaires, or the independent evaluations. These preliminary results warrant further studies with more participants and with more elaborate cognitive testing.Keywords: CBT, attention-deficit/hyperactivity disorder, cognitive testing, non-­pharmacological treatments

Characterization of a synthetic single crystal diamond Schottky diode for radiotherapy electron beam dosimetry.

Science.gov (United States)

Di Venanzio, C; Marinelli, Marco; Milani, E; Prestopino, G; Verona, C; Verona-Rinati, G; Falco, M D; Bagalà, P; Santoni, R; Pimpinella, M

2013-02-01

To investigate the dosimetric properties of synthetic single crystal diamond based Schottky diodes under irradiation with therapeutic electron beams from linear accelerators. A single crystal diamond detector was fabricated and tested under 6, 8, 10, 12, and 15 MeV electron beams. The detector performances were evaluated using three types of commercial detectors as reference dosimeters: an Advanced Markus plane parallel ionization chamber, a Semiflex cylindrical ionization chamber, and a p-type silicon detector. Preirradiation, linearity with dose, dose rate dependence, output factors, lateral field profiles, and percentage depth dose profiles were investigated and discussed. During preirradiation the diamond detector signal shows a weak decrease within 0.7% with respect to the plateau value and a final signal stability of 0.1% (1σ) is observed after about 5 Gy. A good linear behavior of the detector response as a function of the delivered dose is observed with deviations below ±0.3% in the dose range from 0.02 to 10 Gy. In addition, the detector response is dose rate independent, with deviations below 0.3% in the investigated dose rate range from 0.17 to 5.45 Gy∕min. Percentage depth dose curves obtained from the diamond detector are in good agreement with the ones from the reference dosimeters. Lateral beam profile measurements show an overall good agreement among detectors, taking into account their respective geometrical features. The spatial resolution of solid state detectors is confirmed to be better than that of ionization chambers, being the one from the diamond detector comparable to that of the silicon diode. A good agreement within experimental uncertainties was also found in terms of output factor measurements between the diamond detector and reference dosimeters. The observed dosimetric properties indicate that the tested diamond detector is a suitable candidate for clinical electron beam dosimetry.

EPR/alanine dosimetry for two therapeutic proton beams

Energy Technology Data Exchange (ETDEWEB)

Marrale, Maurizio, E-mail: maurizio.marrale@unipa.it [Dipartimento di Fisica e Chimica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo (Italy); Gruppo V Sezione INFN di Catania, Via Santa Sofia, 64, 95123 Catania (Italy); Carlino, Antonio [Dipartimento di Fisica e Chimica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo (Italy); EBG MedAustron GmbH, Marie Curie-Straße 5, A-2700 Wiener Neustadt (Austria); Gallo, Salvatore [Dipartimento di Fisica e Chimica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo (Italy); Gruppo V Sezione INFN di Catania, Via Santa Sofia, 64, 95123 Catania (Italy); Laboratorio PH3DRA, Dipartimento di Fisica e Astronomia, Università di Catania, Via Santa Sofia 64, 95123 Catania (Italy); Longo, Anna; Panzeca, Salvatore [Dipartimento di Fisica e Chimica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo (Italy); Gruppo V Sezione INFN di Catania, Via Santa Sofia, 64, 95123 Catania (Italy); Bolsi, Alessandra; Hrbacek, Jan; Lomax, Tony [Center for Proton Therapy, Paul Scherrer Institute, 5232 Villigen PSI (Switzerland)

2016-02-01

In this work the analysis of the electron paramagnetic resonance (EPR) response of alanine pellets exposed to two different clinical proton beams employed for radiotherapy is performed. One beam is characterized by a passive delivery technique and is dedicated to the eyes treatment (OPTIS2 beam line). Alanine pellets were irradiated with a 70 MeV proton beam corresponding to 35 mm range in eye tissue. We investigated how collimators with different sizes and shape used to conform the dose to the planned target volume influence the delivered dose. For this purpose we performed measurements with varying the collimator size (Output Factor) and the results were compared with those obtained with other dosimetric techniques (such as Markus chamber and diode detector). This analysis showed that the dosimeter response is independent of collimator diameter if this is larger than or equal to 10 mm. The other beam is characterized by an active spot-scanning technique, the Gantry1 beam line (maximum energy 230 MeV), and is used to treat deep-seated tumors. The dose linearity of alanine response in the clinical dose range was tested and the alanine dose response at selected locations in depth was measured and compared with the TPS planned dose in a quasi-clinical scenario. The alanine response was found to be linear in the dose in the clinical explored range (from 10 to 70 Gy). Furthermore, a depth dose profile in a quasi-clinical scenario was measured and compared to the dose computed by the Treatment Planning System PSIPLAN. The comparison of calibrated proton alanine measurements and TPS dose shows a difference under 1% in the SOBP and a “quenching” effect up to 4% in the distal part of SOBP. The positive dosimetric characteristics of the alanine pellets confirm the feasibility to use these detectors for “in vivo” dosimetry in clinical proton beams.

Intention to use hearing aids: a survey based on the theory of planned behavior

Directory of Open Access Journals (Sweden)

Meister H

2014-09-01

Full Text Available Hartmut Meister,1 Linda Grugel,1 Markus Meis2 1Jean Uhrmacher Institute for Clinical ENT Research, University of Cologne, Cologne, Germany; 2Hoerzentrum Oldenburg, Oldenburg, Germany Objective: To determine the intention to use hearing aids (HAs by applying the theory of planned behavior (TPB. Design: The TPB is a widely used decision-making model based on three constructs hypothesized to influence the intention to perform a specific behavior; namely, “attitude toward the behavior”, “subjective norm”, and “behavioral control”. The survey was based on a TPB-specific questionnaire addressing factors relevant to HA provision. Study sample: Data from 204 individuals reporting hearing problems were analyzed. Different subgroups were established according to the stage of their hearing help-seeking. Results: The TPB models’ outcome depended on the subgroup. The intention of those participants who had recognized their hearing problems but had not yet consulted an ear, nose, and throat specialist was largely dominated by the “subjective norm” construct, whereas those who had already consulted an ear, nose, and throat specialist or had already tried out HAs were significantly influenced by all constructs. The intention of participants who already owned HAs was clearly less affected by the “subjective norm” construct but was largely dominated by their “attitude toward HAs”. Conclusion: The intention to use HAs can be modeled on the basis of the constructs “attitude toward the behavior”, “subjective norm”, and “behavioral control”. Individual contribution of the constructs to the model depends on the patient’s stage of hearing help-seeking. The results speak well for counseling strategies that explicitly consider the individual trajectory of hearing help-seeking. Keywords: hearing aid uptake, motivation, attitude, subjective norm, behavioral control

Chronic lymphocytic leukemia-associated chromosomal abnormalities and miRNA deregulation

Directory of Open Access Journals (Sweden)

Kiefer Y

2012-03-01

Full Text Available Yvonne Kiefer1, Christoph Schulte2, Markus Tiemann2, Joern Bullerdiek11Center for Human Genetics, University of Bremen, Bremen, Germany; 2Hematopathology Hamburg, Hamburg, GermanyAbstract: Chronic lymphocytic leukemia is the most common leukemia in adults. By cytogenetic investigations major subgroups of the disease can be identified that reflect different routes of tumor development. Of these chromosomal deviations, trisomy 12 and deletions of parts of either the long arm of chromosome 13, the long arm of chromosome 11, or the short arm of chromosome 17 are most commonly detected. In some of these aberrations the molecular target has been identified as eg, ataxia telangiectasia mutated (ATM in case of deletions of chromosomal region 11q22~23 and the genes encoding microRNAs miR-15a/16-1 as likely targets of deletions of chromosomal band 13q14.3. Of note, these aberrations do not characterize independent subgroups but often coexist within the metaphases of one tumor. Generally, complex aberrations are associated with a worse prognosis than simple karyotypic alterations. Due to smaller sizes of the missing segment the detection of recurrent deletions is not always possible by means of classical cytogenetics but requires more advanced techniques as in particular fluorescence in situ hybridization (FISH. Nevertheless, at this time it is not recommended to replace classical cytogenetics by FISH because this would miss additional information given by complex or secondary karyotypic alterations. However, the results of cytogenetic analyses allow the stratification of prognostic and predictive groups of the disease. Of these, the group characterized by deletions involving TP53 is clinically most relevant. In the future refined methods as eg, array-based comparative genomic hybridization will supplement the existing techniques to characterize CLL. Keywords: chronic lymphocytic leukemia, chromosomal abnormality, miRNA deregulation

Successful application of extracorporeal membrane oxygenation due to pulmonary hemorrhage secondary to granulomatosis with polyangiitis

Directory of Open Access Journals (Sweden)

Hohenforst-Schmidt W

2013-07-01

Full Text Available Wolfgang Hohenforst-Schmidt,1 Arndt Petermann,2 Aikaterini Visouli,3 Paul Zarogoulidis,4 Kaid Darwiche,5 Ioanna Kougioumtzi,6 Kosmas Tsakiridis,3 Nikolaos Machairiotis,6 Markus Ketteler,2 Konstantinos Zarogoulidis,4 Johannes Brachmann11II Medical Clinic, Coburg Clinic, University of Wuerzburg, Coburg, Germany; 2Division of Nephrology, Coburg Clinic, University of Wuerzburg, Coburg, Germany; 3Cardiothoracic Surgery Department, “Saint Luke” Private Hospital, Thessaloniki, Greece; 4Pulmonary Department, “G Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece; 5Department of Interventional Pneumology, Ruhrlandklinik, West German Lung Center, University Hospital, University of Duisburg-Essen, Essen, Germany; 6Surgery Department (National Health System, University General Hospital of Alexandroupolis, Alexandroupolis, GreeceAbstract: Extracorporeal membrane oxygenation (ECMO is increasingly applied in adults with acute refractory respiratory failure that is deemed reversible. Bleeding is the most frequent complication during ECMO support. Severe pre-existing bleeding has been considered a contraindication to ECMO application. Nevertheless, there are cases of successful ECMO application in patients with multiple trauma and hemorrhagic shock or head trauma and intracranial hemorrhage. ECMO has proved to be life-saving in several cases of life-threatening respiratory failure associated with pulmonary hemorrhage of various causes, including granulomatosis with polyangiitis (Wegener’s disease. We successfully applied ECMO in a 65-year-old woman with acute life-threatening respiratory failure due to diffuse massive pulmonary hemorrhage secondary to granulomatosis with polyangiitis, manifested as severe pulmonary-renal syndrome. ECMO sustained life and allowed disease control, together with plasmapheresis, cyclophosphamide, corticoids, and renal replacement therapy. The patient was successfully weaned from ECMO

Gas turbines and operation of gas turbines 2011; Gasturbinen und Gasturbinenbetrieb 2011

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-01

Within the VGB Conference at 11th and 12th May, 2011 in Offenbach/Main (Federal Republic of Germany), the following lectures were held: (1) The future of high temperature gas turbines in power plants (Konrad Vogeler); (2) Development of reliable thermal barrier coatings for high-loaded turbine and combustor parts (Hans-Peter Bossmann); (3) CCPP Irsching 4 with gas turbine SGT5-8000H, on the way to 60 % CC efficiency (Willibald Fischer); (4) First test results of MAN's new 6 MW gas turbine (Markus Beukenberg); (5) Design characteristics and key thermodynamic parameters of the recuperated 4 MW solar turbines Mercury 50 gas turbines: - Economics and environmental feasibility, - operating experience in combined cycle applications with recuperation (Ulrich Stang); (6) Medium size gas turbines - OEM concept for continued reduction of life cycle costs (Vladimir Navrotsky); (7) Fracture mechanical analysis on fatigue failures of gas turbine components: - Root cause analysis - fracture mechanics - stress corrosion cracking - examples of failure analysis (Peter Verstraete); (8) The effectiveness of blade superalloy reheat treatment (Michael Wood); (9) An innovative combustion technology for high efficient gas turbines (Christian Oliver Paschereit); (10) Damping of thermo-acoustic vibrations in gas turbine combustion chambers (Sermed Sadig); (11) Alstom GT13E2 combustor upgrade for Vattenfalls Berlin Mitte combined heat and power plant (Klaus Doebbeling); (12) Optimisation of air inlet filtration for dust, rain and humidity (Heiko Manstein); (13) Life cycle cost reduction through high efficiency membrane based air intake filters (Helmut Krah); (14) Status and impact of national, European and international standardization on GT plants; GT standardizing status quo? (Gerd Weber); (15) Technical and thermodynamic aspects of compresssed air energy storage (Peter Radgen); (16) Requirements on the gas turbine in the course of time - intelligent OEM-concepts to ensure reliable

Status of the laboratory infrastructure for detector calibration and characterization at the European XFEL

Science.gov (United States)

Raab, N.; Ballak, K.-E.; Dietze, T.; Ekmedzič, M.; Hauf, S.; Januschek, F.; Kaukher, A.; Kuster, M.; Lang, P. M.; Münnich, A.; Schmitt, R.; Sztuk-Dambietz, J.; Turcato, M.

2016-12-01

The European X-ray Free Electron Laser (XFEL.EU) will provide unprecedented peak brilliance and ultra-short and spatially coherent X-ray pulses in an energy range of 0.25 to 25 keV . The pulse timing structure is unique with a burst of 2700 pulses of 100 fs length at a temporal distance of 220 ns followed by a 99.4 ms gap. To make optimal use of this timing structure and energy range a great variety of detectors are being developed for use at XFEL.EU, including 2D X-ray imaging cameras that are able to detect images at a rate of 4.5 MHz, provide dynamic ranges up to 105 photons per pulse per pixel under different operating conditions and covering a large range of angular resolution \\cite{requirements,Markus}. In order to characterize, commission and calibrate this variety of detectors and for testing of detector prototypes the XFEL.EU detector group is building up an X-ray test laboratory that allows testing of detectors with X-ray photons under conditions that are as similar to the future beam line conditions at the XFEL.EU as is possible with laboratory sources [1]. A total of four test environments provide the infrastructure for detector tests and calibration: two portable setups that utilize low power X-ray sources and radioactive isotopes, a test environment where a commercial high power X-ray generator is in use, and a pulsed X-ray/electron source which will provide pulses as short as 25 ns in XFEL.EU burst mode combined with target anodes of different materials. The status of the test environments, three of which are already in use while one is in commissioning phase, will be presented as well as first results from performance tests and characterization of the sources.

EPR/alanine dosimetry for two therapeutic proton beams

International Nuclear Information System (INIS)

Marrale, Maurizio; Carlino, Antonio; Gallo, Salvatore; Longo, Anna; Panzeca, Salvatore; Bolsi, Alessandra; Hrbacek, Jan; Lomax, Tony

2016-01-01

In this work the analysis of the electron paramagnetic resonance (EPR) response of alanine pellets exposed to two different clinical proton beams employed for radiotherapy is performed. One beam is characterized by a passive delivery technique and is dedicated to the eyes treatment (OPTIS2 beam line). Alanine pellets were irradiated with a 70 MeV proton beam corresponding to 35 mm range in eye tissue. We investigated how collimators with different sizes and shape used to conform the dose to the planned target volume influence the delivered dose. For this purpose we performed measurements with varying the collimator size (Output Factor) and the results were compared with those obtained with other dosimetric techniques (such as Markus chamber and diode detector). This analysis showed that the dosimeter response is independent of collimator diameter if this is larger than or equal to 10 mm. The other beam is characterized by an active spot-scanning technique, the Gantry1 beam line (maximum energy 230 MeV), and is used to treat deep-seated tumors. The dose linearity of alanine response in the clinical dose range was tested and the alanine dose response at selected locations in depth was measured and compared with the TPS planned dose in a quasi-clinical scenario. The alanine response was found to be linear in the dose in the clinical explored range (from 10 to 70 Gy). Furthermore, a depth dose profile in a quasi-clinical scenario was measured and compared to the dose computed by the Treatment Planning System PSIPLAN. The comparison of calibrated proton alanine measurements and TPS dose shows a difference under 1% in the SOBP and a “quenching” effect up to 4% in the distal part of SOBP. The positive dosimetric characteristics of the alanine pellets confirm the feasibility to use these detectors for “in vivo” dosimetry in clinical proton beams.

A new model for volume recombination in plane-parallel chambers in pulsed fields of high dose-per-pulse.

Science.gov (United States)

Gotz, M; Karsch, L; Pawelke, J

2017-11-01

In order to describe the volume recombination in a pulsed radiation field of high dose-per-pulse this study presents a numerical solution of a 1D transport model of the liberated charges in a plane-parallel ionization chamber. In addition, measurements were performed on an Advanced Markus ionization chamber in a pulsed electron beam to obtain suitable data to test the calculation. The experiment used radiation pulses of 4 μs duration and variable dose-per-pulse values up to about 1 Gy, as well as pulses of variable duration up to 308 [Formula: see text] at constant dose-per-pulse values between 85 mGy and 400 mGy. Those experimental data were compared to the developed numerical model and existing descriptions of volume recombination. At low collection voltages the observed dose-per-pulse dependence of volume recombination can be approximated by the existing theory using effective parameters. However, at high collection voltages large discrepancies are observed. The developed numerical model shows much better agreement with the observations and is able to replicate the observed behavior over the entire range of dose-per-pulse values and collection voltages. Using the developed numerical model, the differences between observation and existing theory are shown to be the result of a large fraction of the charge being collected as free electrons and the resultant distortion of the electric field inside the chamber. Furthermore, the numerical solution is able to calculate recombination losses for arbitrary pulse durations in good agreement with the experimental data, an aspect not covered by current theory. Overall, the presented numerical solution of the charge transport model should provide a more flexible tool to describe volume recombination for high dose-per-pulse values as well as for arbitrary pulse durations and repetition rates.

Examining Dark Triad traits in relation to mental toughness and physical activity in young adults

Directory of Open Access Journals (Sweden)

Sabouri S

2016-01-01

Full Text Available Sarah Sabouri,1 Markus Gerber,2 Dena Sadeghi Bahmani,3 Sakari Lemola,4 Peter J Clough,5 Nadeem Kalak,3 Mahin Shamsi,1 Edith Holsboer-Trachsler,3 Serge Brand2,3 1Faculty of Educational Sciences and Psychology, AllamehTabataba’i University, Tehran, Iran; 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, 3Center for Affective, Stress and Sleep Disorders, Psychiatric Clinics of the University of Basel, 4Faculty of Psychology, University of Basel, Basel, Switzerland; 5Department of Psychology, Manchester Metropolitan University, Manchester, UK Objective: The Dark Triad (DT describes a set of three closely related personality traits: Machiavellianism, narcissism, and psychopathy. Mental toughness (MT refers to a psychological construct combining confidence, commitment, control, and challenge. High MT is related to greater physical activity (PA and, relative to men, women have lower MT scores. The aims of the present study were 1 to investigate the association between DT, MT, and PA, and 2 to compare the DT, MT, and PA scores of men and women.Methods: A total of 341 adults (M=29 years; 51.6% women; range: 18–37 years took part in the study. Participants completed a series of questionnaires assessing DT, MT, and PA.Results: Machiavellianism, narcissism, and psychopathy were all significantly associated with higher MT scores (rs =0.45, 0.50, and 0.20, respectively. DT traits and MT were associated with more vigorous PA. Compared to men, women participants had lower scores for DT traits (overall score and psychopathy, while no differences were found for MT or PA in both sexes.Conclusion: DT traits, high MT, and vigorous PA are interrelated. This pattern of results might explain why, for instance, successful professional athletes can at the same time be tough and ruthless. Keywords: dark triad, mental toughness, physical activity, young adults, sex

SU-F-T-515: Increased Skin Dose in Supine Craniospinal Irradiation Due to Carbon Fiber Couch and Vacuum Bag Immobilization Device

Energy Technology Data Exchange (ETDEWEB)

Robertson, D; Zhao, Z; Wang, X; Yang, J [UT MD Anderson Cancer Center, Houston, TX (United States)

2016-06-15

Purpose: To measure the surface dose for supine craniospinal irradiation employing posterior beams, treating through an imaging couch and BlueBag immobilization device. Methods: The percentage depth dose (PDD) in the buildup region of a clinical 6 MV photon beam was measured using an Advanced Markus parallel plate ionization chamber in a solid water phantom. The PDD from a 10×10 cm{sup 2} anterior beam was measured at 100 cm SSD, simulating a traditional prone craniospinal technique. The measurements were compared to commissioning and treatment planning system data. The PDD was also measured in a posterior setup with the phantom surface laying directly on the Brainlab carbon fiber imaging couch, with the phantom surface 100 cm from the source, simulating a supine craniospinal setup. The posterior measurements were repeated with a BlueBag vacuum immobilization device between the couch and phantom, with thicknesses of 1.7 cm and 5 cm. The PDD from a 10×10 cm{sup 2} field and a typical 6×30 cm{sup 2} craniospinal field were also compared. The PDDs were normalized at 5 cm to reflect typical craniospinal prescription dose normalization. Results: The measured PDD curve from the anterior setup agreed well with commissioning and treatment planning data, with surface doses of 19.9%, 28.8% and 27.7%, respectively. The surface doses of the 10×10 cm{sup 2} and 6×30 cm{sup 2} fields delivered through the imaging couch were both 122.4%. The supine setup yielded surface doses of 122.4%, 121.6%, and 119.6% for the couch only, 1.7 cm bag, and 5 cm bag setups, respectively. Conclusion: Delivering craniospinal irradiation through a carbon fiber couch removes the majority of skin sparing. The addition of a vacuum bag immobilization device restores some skin sparing, but the magnitude of this effect is negligible.

Analysis and reconstructed modelling of the debris flow event of the 21st of July 2012 of St. Lorenzen (Styria, Austira)

Science.gov (United States)

Janu, Stefan; Mehlhorn, Susanne; Moser, Markus

2013-04-01

Analysis and reconstructed modelling of the debris flow event of the 21st of July 2012 of St. Lorenzen (Styria, Austria) Authors: Stefan Janu, Susanne Mehlhorn, Markus Moser The village of St. Lorenzen, in the Styrian Palten valley is situated on the banks of the Lorenz torrent, in which a debris flow event occurred in the early morning hours of the 21st of July 2012, causing catastrophic damage to residential buildings and other infrastructural facilities. In the ministry-approved hazard zone map of 2009, the flood water discharge and bedload volume associated with a 150-year event was estimated at 34 m³/s and 25,000 m³ respectively for the 5.84 km² catchment area. The bedload transport capacity of the torrent was classified as ranging from 'heavy' to 'capable of producing debris flows'. The dominant process type of the mass movement event may be described as a fine-grained debris flow. The damage in the residential area of St.Lorenzen was caused by a debris flow pulse in the lower reach of the Lorenz torrent. This debris flow pulse was in turn caused by numerous landslides along the middle reaches of the torrent, some of which caused blockages, ultimately leading to an outburst event in the main torrent. Discharge cross-sections ranging from 65 - 90 m², and over 100 m² in a few instances, were measured upstream of the St. Lorenzen residential area. Back-calculations of velocities yielded an average debris flow velocity along the middle reaches of the torrent between 11 and 16 m/s. An average velocity of 9 m/s was calculated for the debris flow at the neck of the alluvial fan directly behind the center of the village. Due to both the high discharge values as well as to the height of the mass movement deposits, the natural hazard event of 21 July 2012 in St. Lorenzen is clearly to be described as having had an extreme intensity. A total of 67 buildings were damaged along the Lorenz torrent, 7 of were completely destroyed. According to the Austrian Service for

Detection of central circuits implicated in the formation of novel pain memories

Directory of Open Access Journals (Sweden)

Upadhyay J

2016-09-01

Full Text Available Jaymin Upadhyay,1 Julia Granitzka,1 Thomas Bauermann,2 Ulf Baumgärtner,3 Markus Breimhorst,1 Rolf-Detlef Treede,3 Frank Birklein1 1Department of Neurology, 2Department of Neuroradiology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, 3Department of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM, Heidelberg University, Mannheim, Germany Abstract: Being able to remember physically and emotionally painful events in one’s own past may shape behavior, and can create an aversion to a variety of situations. Pain imagination is a related process that may include recall of past experiences, in addition to production of sensory and emotional percepts without external stimuli. This study aimed to understand 1 the central nervous system processes that underlie pain imagination, 2 the retrieval of pain memories, and 3 to compare the latter with visual object memory. These goals were achieved by longitudinally investigating brain function with functional magnetic resonance imaging in a unique group of healthy volunteers who had never experienced tooth pain. In these subjects, we compared brain responses elicited during three experimental conditions in the following order: imagination of tooth pain (pain imagination, remembering one’s own house (object memory, and remembrance of tooth pain following an episode of induced acute tooth pain (pain memory. Key observations stemming from group-level conjunction analyses revealed common activation in the posterior parietal cortex for both pain imagination and pain memory, while object and pain memory each had strong activation predominantly within the middle frontal gyrus. When contrasting pain imagination and memory, significant activation differences were observed in subcortical structures (ie, parahippocampus – pain imagination > pain memory; midbrain – pain memory > pain imagination. Importantly, these findings were observed in the presence of

Paliperidone extended-release: does it have a place in antipsychotic therapy?

Directory of Open Access Journals (Sweden)

Carlos Schönfeldt-Lecuona

2011-03-01

Full Text Available Maximilian Gahr1,*, Markus A Kölle1,*, Carlos Schönfeldt-Lecuona1, Peter Lepping2, Roland W Freudenmann11Department of Psychiatry and Psychotherapy, University of Ulm, Ulm, Germany; 2Department of Psychiatry, Glyndwr University, Wales, UK *Both authors contributed equally and their order was determined by coin toss.Abstract: Paliperidone (9-hydroxy-risperidone, the active metabolite of risperidone, was approved for treating schizophrenia worldwide in 2006 as paliperidone extended-release (PER, and became the first second-generation antipsychotic specifically licensed for treating schizoaffective disorder in 2009. However, at the same time, its comparatively high cost gave rise to concerns about the cost-effectiveness of PER as compared with its precursor, risperidone. This paper reviews the existing knowledge of the pharmacology, kinetics, efficacy, tolerability, and fields of application of PER, and compares PER with risperidone in order to determine whether it has a place in antipsychotic therapy. An independent assessment of all relevant publications on PER published until July 2010 was undertaken. PER has a unique pharmacological profile, including single dosing, predominantly renal excretion, low drug–drug interaction risk, and differs from risperidone in terms of mode of action and pharmacokinetics. High-level evidence suggests that PER is efficacious and safe in schizophrenia, schizoaffective disorder, and acute manic episodes. There is a striking lack of published head-to-head comparisons between PER and risperidone, irrespective of indication. Low-level evidence shows a lower risk for hyperprolactinemia and higher patient satisfaction with PER than with risperidone. PER adds to the still limited arsenal of second-generation antipsychotics. In the absence of direct comparisons with risperidone, it remains difficult to come to a final verdict on the potential additional therapeutic benefits of PER which would justify its substantially

The current state of physical activity and exercise programs in German-speaking, Swiss psychiatric hospitals: results from a brief online survey

Directory of Open Access Journals (Sweden)

Br

2016-06-01

Full Text Available Serge Brand,1,2 Flora Colledge,2 Nadja Beeler,2 Uwe Pühse,2 Nadeem Kalak,1 Dena Sadeghi Bahmani,1 Thorsten Mikoteit,1 Edith Holsboer-Trachsler,1 Markus Gerber2 1Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders, 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland Background: Physical activity and exercise programs (PAEPs are an important factor in increasing and maintaining physical and mental health. This holds particularly true for patients with psychiatric disorders undergoing treatment in a psychiatric hospital. To understand whether the benefits reported in the literature are mirrored in current treatment modalities, the aim of the present study was to assess the current state of PAEPs in psychiatric hospitals in the German-speaking part of Switzerland. Methods: All psychiatric hospitals (N=55 in the German-speaking part of Switzerland were contacted in spring 2014. Staff responsible for PAEPs were asked to complete an online questionnaire covering questions related to PAEPs such as type, frequency, staff training, treatment rationale, importance of PAEPs within the treatment strategy, and possible avenues to increase PAEPs. Results: Staff members of 48 different psychiatric hospitals completed the survey. Hospitals provided the following therapeutic treatments: relaxation techniques (100%, sports therapy (97%, activity-related psychotherapeutic interventions (95%, physiotherapy (85%, body therapies (59%, far-east techniques (57%, and hippotherapy (22%. Frequencies ranged from once/week to five times/week. Approximately 25% of patients participated in the PAEPs. Interventions were offered irrespective of psychiatric disorders. PAEP providers wanted and needed more vocational training. Conclusion: All participating psychiatric hospitals offer a broad variety of PAEPs in their treatment curricula. However, the majority of inpatients do not

The Consideration of Bolus Effects of Games Attached on Lesion area

International Nuclear Information System (INIS)

Park, Ju Young; Ju, Sang Kyu; Park, Young Chul; Han, Young Yi; Shin, Eun Hyuk; Park, Yong Hwan

2004-01-01

The aim of this study is to evaluate the effect of skin dose and PDD by using wounds protecting gauzes or Vaselinespread gauzes. And it was studied that the possibility to substitute custom bolus into gauzes. 4 MV photon (CL600C, varian, US), Polystyrene Phantom (30(W) X 30(L) X 30(H)) with Markus chamber(PTW, US) were used for dose measurement. This study was distinguished natural gauzes and spread over Vaseline gauzes. We gave variety to the gauze thickness at 5, 10 and 15 sheets respectively. For comparison between using bolus and not that, we had used 1.0 cm thickness bolus so that analyzed surface dose and PDD at the same conditions above mentioned. When maximum point was defined as reference point, surface dose was measured as 35% in open beam. When the gauzes were attached to surface as 5, 10 and 15 sheets, surface dose were increased as 69, 80 and 91% respectively according to thickness of gauzes. When spread over Vaseline gauzes were attached to surface as 5, 10 and 15 sheets, surface dose were increased respectively as 98, 100 and 98% according to thickness of gauzes. Also when 0.5 cm bolus and 5 sheets gauzes were composed, surface dose was measured as 98%. The gauzes that were attached to skin surface in radiation therapy had been scattering material and contributed increasing surface dose without variation of percentage depth dose. However, if we want to delivery much dose to skin surface then we have to apply many sheets of gauzes to skin surface. Although we get easy that result by bolus or spread over Vaseline gauzes, we have to revise percentage depth dose at calculation. Therefore, if we find pertinent conditions based on measured data that are considered skin dose and patient setup efficiency, to replace custom bolus with gauzes will be helpful to efficient treatment.

SU-E-T-446: Evaluation of the Dosimetric Properties of a Diode Detector to Proton Radiosurgery

Energy Technology Data Exchange (ETDEWEB)

Teran, A [Loma Linda University Medical Center, Loma Linda, CA (United States); San Diego State University, San Diego, CA (United States); McAuley, G; Slater, J M [Loma Linda University, Loma Linda, CA (United States); Slater, J D; Wroe, A [Loma Linda University Medical Center, Loma Linda, CA (United States)

2014-06-01

Purpose: To test the PTW PR60020 proton dosimetry diode in radiation fields relevant to proton radiosurgery applications and evaluate its suitability as a high resolution, real time dosimetry device. Methods: Data was collected using our standard nominal radiosurgery energies of 126 MeV and 155 MeV through a single stage scattering system, corresponding to a range of 9.7 and 15 cm in water respectively. Various beam modulations were tested as part of this study. Depth dose and beam profile measurements were completed with the PTW PR60020 dosimetry diode with comparative measurements using a PTW Markus ionization chamber and EBT2 Gafchromic film. Monte Carlo simulations were also completed for comparison. Results: The single 1 mm{sup 2} by 20 μm thick sensitive volume allowed for high spatial resolution measurements while maintaining sufficient sensitive volume to ensure that measurements could be completed without excessive beam delivery. Depth dose profiles exhibited negligible LET dependence which typically impacts film and other solid state dosimetry devices, while beam ranges measured with the PTW diode were within 1 mm of ion chamber data. In an edge on arrangement beam profiles were also measured within 0.5 mm full-width at half-maximum at various depths as compared to film and simulation data. Conclusion: The PTW PR60020 proved to be a very useful radiation metrology apparatus for proton radiosurgery applications. Its waterproof and rugged construction allowed for easy deployment in phantoms or water tanks that are commonly used in proton radiosurgery QA. Dosimetrically, the diode exhibited negligible LET dependence as a function of depth, while in edge on arrangement to the incident proton beam it facilitated the measurement of beam profiles with a spatial resolution comparable to both Monte Carlo and film measurements. This project was sponsored in part by funding from the Department of Defense (DOD# W81XWH-BAA-10-1)

Cross-year peer tutoring on internal medicine wards: results of a qualitative focus group analysis

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Krautter M

2014-09-01

Full Text Available Markus Krautter,1 Sven Andreesen,2 Nadja Köhl-Hackert,2 Katja Hoffmann,3 Wolfgang Herzog,2 Christoph Nikendei2 1Department of Nephrology, University of Heidelberg, 2Department of General Internal Medicine and Psychosomatics, University of Heidelberg Medical Hospital, 3Department of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany Background: Peer-assisted learning (PAL has become a well-accepted teaching method within medical education. However, descriptions of on-ward PAL programs are rare. A focus group analysis of a newly established PAL program on an internal medicine ward was conducted to provide insights into PAL teaching from a student perspective.Purpose: To provide insights into students' experiences regarding their on-ward training with and without accompanying PAL tutors.Methods: A total of N=168 medical students in their sixth semester participated in the investigation (intervention group: N=88; control group: N=80. The intervention group took part in the PAL program, while the control group received standard on-ward training. There were seven focus groups with N=43 participants (intervention group: four focus groups, N=28 participants; control group: three focus groups, N=15 participants. The discussions were analyzed using content analysis.Results: The intervention group emphasized the role of the tutors as competent and well-trained teachers, most beneficial in supervising clinical skills. Tutors motivate students, help them to integrate into the ward team, and provide a non-fear-based working relationship whereby students' anxiety regarding working on ward decreases. The control group had to rely on autodidactic learning strategies when neither supervising physicians nor final-year students were available.Conclusion: On-ward PAL programs represent a particularly valuable tool for students' support in training clinical competencies on ward. The tutor–student working alliance

Local anesthetics for brain tumor resection: current perspectives

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Potters JW

2018-02-01

Full Text Available Jan-Willem Potters, Markus Klimek Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands Abstract: This review summarizes the added value of local anesthetics in patients undergoing craniotomy for brain tumor resection, which is a procedure that is carried out frequently in neurosurgical practice. The procedure can be carried out under general anesthesia, sedation with local anesthesia or under local anesthesia only. Literature shows a large variation in the postoperative pain intensity ranging from no postoperative analgesia requirement in two-thirds of the patients up to a rate of 96% of the patients suffering from severe postoperative pain. The only identified causative factor predicting higher postoperative pain scores is infratentorial surgery. Postoperative analgesia can be achieved with multimodal pain management where local anesthesia is associated with lower postoperative pain intensity, reduction in opioid requirement and prevention of development of chronic pain. In awake craniotomy patients, sufficient local anesthesia is a cornerstone of the procedure. An awake craniotomy and brain tumor resection can be carried out completely under local anesthesia only. However, the use of sedative drugs is common to improve patient comfort during craniotomy and closure. Local anesthesia for craniotomy can be performed by directly blocking the six different nerves that provide the sensory innervation of the scalp, or by local infiltration of the surgical site and the placement of the pins of the Mayfield clamp. Direct nerve block has potential complications and pitfalls and is technically more challenging, but mostly requires lower total doses of the local anesthetics than the doses required in surgical-site infiltration. Due to a lack of comparative studies, there is no evidence showing superiority of one technique versus the other. Besides the use of other local anesthetics for analgesia, intravenous lidocaine administration has

A comparison of protocols for external beam radiotherapy beam calibrations

International Nuclear Information System (INIS)

Saeed Al-Ahbabi, Salma; Bradley, D.A.; Beyomi, M.; Alkatib, Z.; Adhaheri, S.; Darmaki, M.; Nisbet, A.

2012-01-01

A number of codes of practice (CoP) for electron and photon radiotherapy beam dosimetry are currently in use. Comparison is made of the more widely used of these, specifically those of the International Atomic Energy Agency (IAEA TRS-398), the American Association of Physicists in Medicine (AAPM TG-51) and the Institute of Physics and Engineering in Medicine (IPEM 2003). All are based on calibration of ionization chambers in terms of absorbed dose to water, each seeking to reduce uncertainty in delivered dose, providing an even stronger system of primary standards than previous air-kerma based approaches. They also provide a firm, traceable and straight-forward formalism. Included in making dose assessments for the three CoP are calibration coefficients for a range of beam quality indices. Measurements have been performed using clinical photon and electron beams, the absorbed dose to water being obtained following the recommendations given by each code. Electron beam comparisons have been carried out using measurements for electron beams of nominal energies 6, 9, 12, 16 and 20 MeV. Comparisons were also carried out for photon beams of nominal energies 6 and 18 MV. For photon beams use was made of NE2571 cylindrical graphite walled ionization chambers, cross-calibrated against an NE2611 Secondary Standard; for electron beams, PTW Markus and NACP-02 plane-parallel chambers were used. Irradiations were made using Varian 600C/2100C linacs, supported by water tanks and Virtual Water™ phantoms. The absorbed doses for photon and electron beams obtained following these CoP are all in good agreement, with deviations of less than 2%. A number of studies have been carried out by different groups in different countries to examine the consistency of dosimetry codes of practice or protocols. The aim of these studies is to confirm that the goal of those codes is met, namely uniformity in establishment of dosimetry of all radiation beam types used in cancer therapy in the world

Towards managing diversity: Cultural aspects of conflict management in organizations

Directory of Open Access Journals (Sweden)

Dorothea Hamdorf

2003-10-01

Full Text Available This study investigated cultural aspects of conflict management in organizations in response to the growing need for an understanding of how people from diverse cultural backgrounds can work together without the often-resulting problem of intercultural conflict. Culture was evaluated through self-assessments of how independent or interdependent the subjects were (Markus & Kitayama, 1991, and conflict behavior through eight conflict management styles: dominating, integrating, compromising, avoiding, obliging, emotion, neglect and third-party help (Rahim, 1983; Ting-Toomey et al., 2000. Furthermore, drawing upon face-negotiation theory (Ting-Toomey, 1988; Ting-Toomey & Kurogi, 1998, a test was made of whether self-face, other-face and mutual-face concerns could explain cultural differences in conflict behavior. A total of 185 professionals from different countries completed an Internet questionnaire. An exploratory factor analysis of the eight styles revealed three factors which seem to describe direct, indirect and integrating plus compromising conflict behaviors. In line with this study's hypotheses, persons with a tendency to act independently mentioned direct styles, as well as integrating, and persons with a tendency to act interdependently mentioned indirect styles in addition to integrating and compromising. Furthermore, a concern for self-face maintenance was related to direct conflict behavior, a concern for other-face maintenance to indirect conflict behavior, and a concern for mutual-face maintenance to integrating and compromising. However, persons with a tendency to act independently do not seem to be particularly concerned about self-face maintenance. Persons with a tendency to act interdependently, on the other hand, show other- and mutual-face concerns in conflict situations. It was concluded that face concerns do play a crucial role, but mainly in explaining the conflict behavior of persons with a tendency to act interdependently

Global Warming and Geographically Scalar Climatic Objects Exist: An Ontologically Realist and Object-Oriented Analysis of the Daymet TMAX Climate Summaries for North America

Science.gov (United States)

Jackson, C. P.

2017-12-01

The scientific materialist worldview, what Peter Unger refers to as the Scientiphical worldview, or Scientiphicalism, has been utterly catastrophic for mesoscale objects in general, but, with its closely associated twentieth-century formal logic, this has been especially true for notoriously vague things like climate change, coastlines, mountains and dust storms. That is, any so-called representations or references ultimately suffer the same ontological demise as their referents, no matter how well-defined their boundaries may in fact be. Against this reductionist metaphysics, climatic objects are discretized within three separate ontologically realist systems, Graham Harman's object-oriented philosophy, or ontology (OOO), Markus Gabriel's ontology of fields of sense (OFS) and Tristan Garcia's two systems and new order of time, so as to make an ontological case for any geographically scalar object, beginning with pixels, as well as any notoriously vague thing they are said to represent. Four-month overlapping TMAX seasonals were first developed from the Oak Ridge National Laboratory (ORNL) Daymet climate temperature maximum (TMAX) monthly summaries (1980-2016) for North America and segmented within Trimble's eCognition Developer using the simple and widely familiar quadtree algorithm with a scale parameter of four, in this example. The regression coefficient was then calculated for the resulting 37-year climatic objects and an equally simple classification was applied. The same segmentation and classification was applied to the Daymet annual summaries, as well, for comparison. As was expected, the mean warming and cooling trends are lowest for the annual summary TMAX climatic objects. However, the Fall (SOND) season has the largest and smallest areas of warming and cooling, respectively, and the highest mean trend for warming objects. Conversely, Spring (MAMJ) has the largest and smallest areas undergoing cooling and warming, respectively. Finally, Summer (JJAS

Utilization of agrarian potentials'. Challenges for agriculturists and society; Agrar-Potenziale nutzen.. Herausforderung fuer Landwirte und Gesellschaft

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

Within the scope of the meeting 'Utilization of agrarian potentials' held by Deutsche Landwirtschaftliche Gesellschaft e.V. at 8th to 10th January, 2008, in Muenster (Federal Republic of Germany) the following lectures were held: (a) The world markets move - challenges for production (Joachim von Braun); (b) Global markets - future terms of references for the agriculture: guidelines for future strategies under new objectives (Juergen Zeddies); (c) Structural change and globalization - challenges for cooperative societies as market partners of the agriculture (Andreas Schueren, Dieter Hake); (d) More efficient utilization of scarce resources - we need changed thought patterns and decision patterns (Carl-Albrecht Bartmer); (e) Optimal intensities in the agriculture - the requirement of the hour: Adjustment of production at optimal intensity (Theo Jachmann); (f) Growth potentials of selected locations for the agriculture - area productivity in the international comparison (Klaus Nehring); (g) Optimization of the intensities in the crop farming - new challenges, possible adjustments (Hubertus Paetow); (h) Considering inventory management? The fertilization of tomorrow (Klaus Muenchhoff); (i) Value added chain of grain - quality requirements from the view of the traceability: The test system grain (Petra Melisch); (j) Young farmers full of optimism - current results of interview for the estimation of the situation and future and to efficiency potentials (Marika Prasser-Strith); (k) The responsibility for the soil - challenges at technology for cultivation and tillage (Franz-Georg von Busse); (l) The sustainable use of the plough land is an obligation - plough land is precious. (Lothar Hoevelmann); (m) Development of milk cattle companies till 2015 - strategic future planning now necessarily (Johannes Thomsen); (n) The ethical responsibility for a sustainable and global development - agriculture and nutrition (Beatrice van Saan-Klein, Markus Vogt); (o) Ethical

A dosimetry study comparing NCS report-5, IAEA TRS-381, AAPM TG-51 and IAEA TRS-398 in three clinical electron beam energies

International Nuclear Information System (INIS)

Palmans, Hugo; Nafaa, Laila; Patoul, Nathalie de; Denis, Jean-Marc; Tomsej, Milan; Vynckier, Stefaan

2003-01-01

New codes of practice for reference dosimetry in clinical high-energy photon and electron beams have been published recently, to replace the air kerma based codes of practice that have determined the dosimetry of these beams for the past twenty years. In the present work, we compared dosimetry based on the two most widespread absorbed dose based recommendations (AAPM TG-51 and IAEA TRS-398) with two air kerma based recommendations (NCS report-5 and IAEA TRS-381). Measurements were performed in three clinical electron beam energies using two NE2571-type cylindrical chambers, two Markus-type plane-parallel chambers and two NACP-02-type plane-parallel chambers. Dosimetry based on direct calibrations of all chambers in 60 Co was investigated, as well as dosimetry based on cross-calibrations of plane-parallel chambers against a cylindrical chamber in a high-energy electron beam. Furthermore, 60 Co perturbation factors for plane-parallel chambers were derived. It is shown that the use of 60 Co calibration factors could result in deviations of more than 2% for plane-parallel chambers between the old and new codes of practice, whereas the use of cross-calibration factors, which is the first recommendation in the new codes, reduces the differences to less than 0.8% for all situations investigated here. The results thus show that neither the chamber-to-chamber variations, nor the obtained absolute dose values are significantly altered by changing from air kerma based dosimetry to absorbed dose based dosimetry when using calibration factors obtained from the Laboratory for Standard Dosimetry, Ghent, Belgium. The values of the 60 Co perturbation factor for plane-parallel chambers (k att · k m for the air kerma based and p wall for the absorbed based codes of practice) that are obtained from comparing the results based on 60 Co calibrations and cross-calibrations are within the experimental uncertainties in agreement with the results from other investigators

Development of hypertension in overweight adolescents: a review

Directory of Open Access Journals (Sweden)

Kelly RK

2015-10-01

Full Text Available Rebecca K Kelly,1 Costan G Magnussen,1,2 Matthew A Sabin,3 Michael Cheung,3 Markus Juonala3–5 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia; 2Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; 3Murdoch Childrens Research Institute, Royal Children's Hospital and University of Melbourne, Parkville, Australia; 4Department of Medicine, University of Turku, 5Division of Medicine, Turku University Hospital, Turku, Finland Abstract: The upward trend in adolescent hypertension is widely attributed to the adolescent obesity epidemic. Secular trends in adolescent prehypertension and hypertension have risen in congruence with increasing trends in the prevalence of overweight and obesity. The correlation between body mass index and blood pressure in adolescence is moderate to strong in most studies and strongest in those classified as overweight or obese. The mechanisms relating to the development of hypertension in overweight adolescents are unclear; however, a number of nonmodifiable and modifiable factors have been implicated. Importantly, certain clinical and biochemical markers in overweight adolescents are indicative of high risk for hypertension, including family history of hypertension and hyperinsulinemia. These characteristics may prove useful in stratifying overweight adolescents as high or low risk of comorbid hypertension. The treatment of overweight and obesity related hypertension in this population focuses on two key modalities: lifestyle change and pharmacotherapy. These approaches focus almost exclusively on weight reduction; however, a number of emerging strategies target hypertension more specifically. Among adolescents with overt hypertension there are also several factors that indicate higher risk of concurrent subclinical disease, persistent adult hypertension, and adult cardiovascular disease. This group may benefit substantially from more

Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy

Directory of Open Access Journals (Sweden)

Schaffran T

2014-07-01

Full Text Available Tanja Schaffran,1 Nan Jiang,1 Markus Bergmann,2,3 Ekkehard Küstermann,4 Regine Süss,5 Rolf Schubert,5 Franz M Wagner,6 Doaa Awad,7 Detlef Gabel1,2,8 1Department of Chemistry, University of Bremen, 2Institute of Neuropathology, Klinikum Bremen-Mitte; 3Cooperative Center Medicine, University of Bremen, 4“In-vivo-MR” AG, FB2, University of Bremen, Bremen, 5Pharmaceutical Technology, University of Freiburg, Freiburg im Breisgau, 6Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II, Technische Unversitaet Muenchen, Garching, Germany; 7Department of Biochemistry, Alexandria University, Alexandria, Egypt; 8School of Engineering and Science, Jacobs University Bremen, Bremen, Germany Abstract: The potential of boron-containing lipids with three different structures, which were intended for use in boron neutron capture therapy, was investigated. All three types of boron lipids contained the anionic dodecaborate cluster as the headgroup. Their effects on two different tumor models in mice following intravenous injection were tested; for this, liposomes with boron lipid, distearoyl phosphatidylcholine, and cholesterol as helper lipids, and containing a polyethylene glycol lipid for steric protection, were administered intravenously into tumor-bearing mice (C3H mice for SCCVII squamous cell carcinoma and BALB/c mice for CT26/WT colon carcinoma. With the exception of one lipid (B-THF-14, the lipids were well tolerated, and no other animal was lost due to systemic toxicity. The lipid which led to death was not found to be much more toxic in cell culture than the other boron lipids. All of the lipids that were well tolerated showed hemorrhage in both tumor models within a few hours after administration. The hemorrhage could be seen by in vivo magnetic resonance and histology, and was found to occur within a few hours. The degree of hemorrhage depended on the amount of boron administered and on the tumor model. The observed unwanted effect of the lipids

Formation of Polycyclic Aromatic Hydrocarbons and Nitrogen Containing Polycyclic Aromatic Compounds in Titan's Atmosphere, the Interstellar Medium and Combustion

Science.gov (United States)

Landera, Alexander

2013-12-01

Several different mechanisms leading to the formation of (substituted) naphthalene and azanaphthalenes were examined using theoretical quantum chemical calculations. As a result, a series of novel synthetic routes to Polycyclic Aromatic Hydrocarbons (PAHs) and Nitrogen Containing Polycyclic Aromatic Compounds (N-PACs) have been proposed. On Earth, these aromatic compounds originate from incomplete combustion and are released into our environment, where they are known to be major pollutants, often with carcinogenic properties. In the atmosphere of a Saturn's moon Titan, these PAH and N-PACs are believed to play a critical role in organic haze formation, as well as acting as chemical precursors to biologically relevant molecules. The theoretical calculations were performed by employing the ab initio G3(MP2,CC)/B3LYP/6-311G** method to effectively probe the Potential Energy Surfaces (PES) relevant to the PAH and N-PAC formation. Following the construction of the PES, Rice-Ramsperger-Kassel-Markus (RRKM) theory was used to evaluate all unimolecular rate constants as a function of collision energy under single-collision conditions. Branching ratios were then evaluated by solving phenomenological rate expressions for the various product concentrations. The most viable pathways to PAH and N-PAC formation were found to be those where the initial attack by the ethynyl (C2H) or cyano (CN) radical toward a unsaturated hydrocarbon molecule led to the formation of an intermediate which could not effectively lose a hydrogen atom. It is not until ring cyclization has occurred, that hydrogen elimination leads to a closed shell product. By quenching the possibility of the initial hydrogen atom elimination, one of the most competitive processes preventing the PAH or N-PAC formation was avoided, and the PAH or N-PAC formation was allowed to proceed. It is concluded that these considerations should be taken into account when attempting to explore any other potential routes towards

SU-F-T-138: Commissioning and Evaluating Dose Computation Models for a Dedicated Proton Line Scanning Beam Nozzle in Eclipse Treatment Planning System

Energy Technology Data Exchange (ETDEWEB)

Tsai, P [Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Tao-yuan, Taiwan (China); Chang Gung University, Taoyuan, Taiwan (China); Huang, H; Cai, S; Chen, H; Wu, S; Wu, T; Lee, S; Yeh, C; Wu, T [Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Tao-yuan, Taiwan (China); Lee, C [Chang Gung University, Taoyuan, Taiwan (China)

2016-06-15

Purpose: In this study, we present an effective method to derive low dose envelope of the proton in-air spot fluence at beam positions other than the isocenter to reduce amount of measurements required for planning commission. Also, we demonstrate commissioning and validation results of this method to the Eclipse treatment planning system (version 13.0.29) for a Sumitomo dedicated proton line scanning beam nozzle. Methods: The in-air spot profiles at five beam-axis positions (±200, ±100 and 0 mm) were obtained in trigger mode using a MP3 Water tank (PTW-Freiburg) and a pinpoint ionization chamber (model 31014, PTW-Freiburg). Low dose envelope (below 1% of the center dose) of the spot profile at isocenter was obtained by repeated point measurements to minimize dosimetry uncertainty. The double Gaussian (DG) model was used to fit and obtain optimal σ1, σ2 and their corresponding weightings through our in-house MATLAB (Mathworks) program. σ1, σ2 were assumed to expand linearly along the beam axis from a virtual source position calculated by back projecting fitted sigmas from the single Gaussian (SG) model. Absolute doses in water were validated using an Advanced Markus chamber at the depth of 2cm with Pristine Peak (BP) R90d ranging from 5–32 cm for 10×10 cm2 scanned fields. The field size factors were verified with square fields from 2 to 20 cm at 2cm and before BP depth. Results: The absolute dose outputs were found to be within ±3%. For field size factor, the agreement between calculated and measurement were within ±2% at 2cm and ±3% before BP, except for the field size below 2×2 cm2. Conclusion: The double Gaussian model was found to be sufficient for characterizing the Sumitomo dedicated proton line scanning nozzle. With our effective double Gaussian fitting method, we are able to save significant proton beam time with acceptable output accuracy.

Perfectionism related to self-reported insomnia severity, but not when controlled for stress and emotion regulation

Directory of Open Access Journals (Sweden)

Br

2015-02-01

Full Text Available Serge Brand,1,2 Roumen Kirov,3 Nadeem Kalak,1 Markus Gerber,2 Uwe Pühse,2 Sakari Lemola,4 Christoph U Correll,5 Samuele Cortese,6–8 Till Meyer,1 Edith Holsboer-Trachsler1 1Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders (ZASS, Basel, Switzerland; 2Department of Sport, Exercise and Health, Division of Sport Science, University of Basel, Basel, Switzerland; 3Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria; 4Faculty of Psychology, University of Basel, Basel, Switzerland; 5Division of Psychiatric Research, North Shore – Long Island Jewish Health System, Zucker Hillside Hospital, NY, USA; 6School of Medicine, University of Nottingham UK; 7Centre for ADHD and Neuro-developmental Disorders Across Lifespan, Institute of Mental Health, University of Nottingham UK; 8New York University Child Study Centre, New York, NY, USA Background: Perfectionism is understood as a set of personality traits such as unrealistically high and rigid standards for performance, fear of failure, and excessive self-criticism. Previous studies showed a direct association between increased perfectionism and poor sleep, though without taking into account possible mediating factors. Here, we tested the hypothesis that perfectionism was directly associated with poor sleep, and that this association collapsed, if mediating factors such as stress and poor emotion regulation were taken into account. Methods: Three hundred and forty six young adult students (M=23.87 years completed questionnaires relating to perfectionism traits, sleep, and psychological functioning such as stress perception, coping with stress, emotion regulation, and mental toughness. Results: Perfectionism was directly associated with poor sleep and poor psychological functioning. When stress, poor coping, and poor emotion regulation were entered in the equation, perfectionism traits no longer contributed substantively to the explanation

Proceedings of the 6th international workshop on top-quark physics. TOP 2013

International Nuclear Information System (INIS)

Husemann, Ulrich; Mildner, Hannes; Roscher, Frank

2014-09-01

The 6th International Workshop on Top-Quark Physics (TOP 2013) took place in Durbach, Germany, between September 14-19, 2013. Physicists from all over the world reported on the latest theoretical and experimental results on the physics of the top quark and discussed perspectives for the research field. While the weather in Durbach didn't always keep the promise, the scientific program certainly did: the 125 participants followed 50 plenary presentations in 15 topical sessions, complemented by a poster session in picturesque Staufenberg castle, in which 20 young scientist discussed their work over tarte flambee and and a glass of wine in front of their posters. All participants could vote for the best poster and the three best posters received prizes. In two question-and-answer sessions young physicists had the opportunity to meet world experts on top-quark physics in an informal atmosphere. The excursion brought the participants to the city of Strasbourg, France, with a boat trip on the Ill river and strolls through Strasbourg's beautiful old town. The TOP 2013 conference was co-organized by Karlsruhe Institute of Technology (KIT), DESY, and the University of Hamburg. We gratefully acknowledge the financial support the conference received from the DFG, the Helmholtz Alliance ''Physics at the Terascale'', the KIT Center Elementary Particle and Astroparticle Physics and from Blue Yonder. The conference would not have been possible without many helpers. First and foremost, we would like to thank our conference secretary, Mrs. Baerbel Braeunling. We would also like to thank the technical support team for the sessions (Martin Goerner, Steffen Roecker, Frank Roscher, Eike Schlieckau, Markus Seidel, Shawn Williamson), and the staff at Hotel Vier Jahreszeiten. We also thank Britta Liebaug for the design of the poster and the web page and Kirsten Sachs for her support in publishing these proceedings. Last but not least, the German top physics

ELEVATE: an innovative study design to assess the efficacy, safety, and evolution of cardiovascular parameters in de novo kidney transplant recipients after early conversion from a calcineurin inhibitor to everolimus

Directory of Open Access Journals (Sweden)

van der Giet M

2014-03-01

Full Text Available Markus van der Giet,1 Josep M Cruzado,2 Johan W de Fijter,3 Hallvard Holdaas,4 Zailong Wang,5 Antonio Speziale,6 Guido Junge61Department of Nephrology, Campus Benjamin Franklin, Charite'-Universitätsmedizin, Berlin, Germany; 2Department of Nephrology, University Hospital of Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain; 3Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands; 4Section of Nephrology, Department of Transplant Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; 5Biometrics and Statistical Science, Novartis Pharmaceuticals, East Hanover, NJ, USA; 6Research and Development, Novartis Pharma AG, Basel, SwitzerlandAbstract: Progressive decline in allograft function and cardiovascular mortality after kidney transplantation remain major clinical challenges that can potentially be addressed by the mammalian target of rapamycin (mTOR inhibitors, everolimus and sirolimus. mTOR inhibitors maintain immunosuppressive efficacy after minimization of calcineurin inhibitor (CNI therapy and can achieve significant long-term improvements in renal function. Recently, data have accumulated that suggest mTOR inhibitors may offer cardioprotective effects. In animal models, inhibition of mTOR leads to regression of cardiac hypertrophy, and the limited data consistently point to a remodeling benefit following heart transplantation. Experimentally, mTOR inhibitors restrict atherogenesis, confirmed clinically by intravascular ultrasound data demonstrating lower rates of transplant vasculopathy in heart transplant recipients on everolimus. Lastly, mTOR inhibitors appear to ameliorate arterial stiffness, a known risk factor for post-transplant cardiovascular events, but data remain sparse. The ELEVATE study will examine the renal effect of early conversion from CNI therapy to everolimus after kidney transplantation. Key secondary endpoints include the change in left ventricular mass index, the first time

Swallowing difficulties with medication intake assessed with a novel self-report questionnaire in patients with systemic sclerosis – a cross-sectional population study

Directory of Open Access Journals (Sweden)

Messerli M

2017-09-01

Full Text Available Markus Messerli,1,2 Rebecca Aschwanden,1 Michael Buslau,2 Kurt E Hersberger,1 Isabelle Arnet1 1Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland; 2European Centre for the Rehabilitation of Scleroderma, Reha Rheinfelden, Rheinfelden, Switzerland Objectives: To assess subjective swallowing difficulties (SD with medication intake and their practical consequences in patients suffering from systemic sclerosis (SSc with a novel self-report questionnaire.Design and setting: Based on a systematic literature review, we developed a self-report questionnaire and got it approved by an expert panel. Subsequently, we sent the questionnaire by post mail to SSc patients of the European Center for the Rehabilitation of Scleroderma Rheinfelden, Switzerland.Participants: Patients were eligible if they were diagnosed with SSc, treated at the center, and were of age ≥18 years at the study start.Main outcome measures: Prevalence and pattern of SD with oral medication intake, including localization and intensity of complaints.Results: The questionnaire consisted of 30 items divided into five sections Complaints, Intensity, Localization, Coping strategies, and Adherence. Of the 64 SSc patients eligible in 2014, 43 (67% returned the questionnaire. Twenty patients reported SD with medication intake (prevalence 47%, either currently (11; 26% or in the past that had been overcome (9; 21%. Self-reported SD were localized mostly in the larynx (43% and esophagus (34%. They were of moderate (45% or strong to unbearable intensity (25%. Modification of the dosage form was reported in 40% of cases with SD. Adherence was poor for 20 (47% patients and was not associated with SD (p=0.148.Conclusion: Our novel self-report questionnaire is able to assess the pattern of complaints linked to medication intake, that is, localization and intensity. It may serve as a guide for health care professionals in selecting the most

SU-F-T-621: Impact of Vacuum and Treatment Couch On Surface Dose in Stereotactic Body Radiation Therapy With and Without a Flattening Filter

Energy Technology Data Exchange (ETDEWEB)

Lan, HT; Lu, SH; Kuo, SH; Tsai, YC; Chen, LH; Wen, SY; Wang, CW [National Taiwan University Hospital, Taipei City, Taiwan (China)

2016-06-15

Purpose: When treating lung cancer patients with stereotactic body radiation therapy (SBRT), better immobilization is needed for accurate delivery of high-dose radiation. However, using a treatment couch (TrueBeamTM) and vacuum bag (BlueBAGTM) may increase the surface dose and skin toxicity. This study investigated the influence of couch and vacuum bag on the surface dose. Methods: The relative surface dose (D{sub 0}/DMAX) was measured in an ion-chamber (Markus-type PTW, 0.05cm{sup 3}) with a solid water phantom and SSD to 100 cm. A comprehensive comparison of different parameter settings, including the different energies (6MV-FFF, 10MV-FF, and 10MV-FFF), field sizes (3 X 3 cm{sup 2}, 5 × 5 cm{sup 2}, 8 × x cm{sup 2} , 10 × 10 cm{sup 2}, and 15 × 15 cm{sup 2}), thickness of the vacuum bag (5mm, 15mm, 30mm, 39mm and 55mm), and couch (with and without), was performed. Results: The FFF increases the surface dose as compared to FF mode. In a similar setting with field of 10 × 10 cm{sup 2}, FFF mode increases the surface dose from 26.0% to 32.8% for 6 MV, and 17.4% to 21.5% for 10 MV. When the beam passes through the couch, the surface dose increases to 3.6, 4.6, 2.9, and 3.7 times for 6 MV-FF, 10 MV-FF, 6 MV-FFF, and 10 MV-FFF, respectively. At the same energy, the surface dose increases to 3.93, 4.11, 4.23, 4.16 and 4.24 times at 5 mm, 15 mm, 30 mm, 39 mm and 55 mm thickness of the vacuum, respectively. Conclusion: Using a couch and vacuum significantly increases the surface dose. For SBRT with a superficial target close to the couch and immobilization vacuum, reduction of vacuum thickness and careful attention to skin dose in planning would be helpful in avoiding severe skin toxicity.

Proceedings of the 6th international workshop on top-quark physics. TOP 2013

Energy Technology Data Exchange (ETDEWEB)

Husemann, Ulrich; Mildner, Hannes; Roscher, Frank (eds.)

2014-09-15

The 6th International Workshop on Top-Quark Physics (TOP 2013) took place in Durbach, Germany, between September 14-19, 2013. Physicists from all over the world reported on the latest theoretical and experimental results on the physics of the top quark and discussed perspectives for the research field. While the weather in Durbach didn't always keep the promise, the scientific program certainly did: the 125 participants followed 50 plenary presentations in 15 topical sessions, complemented by a poster session in picturesque Staufenberg castle, in which 20 young scientist discussed their work over tarte flambee and and a glass of wine in front of their posters. All participants could vote for the best poster and the three best posters received prizes. In two question-and-answer sessions young physicists had the opportunity to meet world experts on top-quark physics in an informal atmosphere. The excursion brought the participants to the city of Strasbourg, France, with a boat trip on the Ill river and strolls through Strasbourg's beautiful old town. The TOP 2013 conference was co-organized by Karlsruhe Institute of Technology (KIT), DESY, and the University of Hamburg. We gratefully acknowledge the financial support the conference received from the DFG, the Helmholtz Alliance ''Physics at the Terascale'', the KIT Center Elementary Particle and Astroparticle Physics and from Blue Yonder. The conference would not have been possible without many helpers. First and foremost, we would like to thank our conference secretary, Mrs. Baerbel Braeunling. We would also like to thank the technical support team for the sessions (Martin Goerner, Steffen Roecker, Frank Roscher, Eike Schlieckau, Markus Seidel, Shawn Williamson), and the staff at Hotel Vier Jahreszeiten. We also thank Britta Liebaug for the design of the poster and the web page and Kirsten Sachs for her support in publishing these proceedings. Last but not least, the German top physics

Dosimetry of small electron fields shaped by lead

International Nuclear Information System (INIS)

Perez, M.; Hill, R.; Whitaker, M.; Greig, L.; West, M.; Jones, L.

2000-01-01

Full text: Electron fields can be used to treat superficial cancers. Field shaping can be achieved by placing lead on the patient surface to minimise the dose to surrounding areas and may improve beam penumbra compared to using standard applicators. However, significant dosimetry changes under high density material edges for electron fields have been reported (W Pohlit and KH Manegold, cited in The Physics of Radiation Therapy, P.M. Khan, 1994). This project evaluated the dosimetry of small dimension electron fields shaped with lead placed on the surface. Comparisons were made between circular lead cutouts (3 and 5cm diameters) and an open electron applicator (5cm diameter). For each of these fields depth doses and profiles were measured using a diode detector in a water phantom, and isodoses were measured using X-Omat film sandwiched within a Solid water phantom. Output factors were measured in the Solid water using a Markus parallel plate ionisation chamber. The effect of the lead thickness on the profiles and output was quantified and the thickness used for the final measurements selected so as to give less than 5% transmission of the primary dose. Penumbral widths for 6MeV and 8MeV using the lead cutouts showed distinct differences compared with the open applicator. At depths of the 90% relative dose the profiles for lead shaped fields showed tighter penumbra widths by an average of 2 mm. This became more pronounced nearer the surface where, at 2mm depth, the difference in penumbral widths was an average of 4mm. The 3cm lead cutouts showed surface dose increases of 6% and 9% for 6MeV and 8 MeV respectively. Depth dose parameters (D max and R 90 ) varied by no more than 2mm between the lead cutouts and the open applicator measurements. Lead can be used to shape electron fields for radiotherapy treatments. Depth dose characteristics do not vary significantly with a 5 cm circular applicator. The penumbral width indicates less isodose spread for the lead cutout

Peak oxygen uptake and left ventricular ejection fraction, but not depressive symptoms, are associated with cognitive impairment in patients with chronic heart failure

Directory of Open Access Journals (Sweden)

Steinberg G

2011-12-01

Full Text Available Gerrit Steinberg1,2*, Nicole Lossnitzer2*, Dieter Schellberg2, Thomas Mueller-Tasch2, Carsten Krueger3, Markus Haass4, Karl Heinz Ladwig5, Wolfgang Herzog2, Jana Juenger21University Hospital of Psychiatry, University of Bern, Bern, Switzerland; 2Department of Psychosomatic and General Internal Medicine, Medical Hospital, University of Heidelberg, Heidelberg, 3Department of Cardiology, Josefs Hospital, Heidelberg, 4Department of Cardiology, Theresien Hospital, Mannheim, 5Institute of Epidemiology, German Research Center for Environmental Health, Munich, Germany*both authors contributed equally to this paperBackground: The aim of the present study was to assess cognitive impairment in patients with chronic heart failure (CHF and its associations with depressive symptoms and somatic indicators of illness severity, which is a matter of controversy.Methods and results: Fifty-five patients with CHF (mean age 55.3 ± 7.8 years; 80% male; New York Heart Association functional class I–III underwent assessment with an expanded neuropsychological test battery (eg, memory, complex attention, mental flexibility, psychomotor speed to evaluate objective and subjective cognitive impairment. Depressive symptoms were assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID and a self-report inventory (Hospital Anxiety and Depression Scale [HADS]. A comprehensive clinical dataset, including left ventricular ejection fraction, peak oxygen uptake, and a 6-minute walk test, was obtained for all patients. Neuropsychological functioning revealed impairment in 56% of patients in at least one measure of our neuropsychological test battery. However, the Mini Mental State Examination (MMSE could only detect cognitive impairment in 1.8% of all patients, 24% had HADS scores indicating depressive symptoms, and 11.1% met SCID criteria for a depressive disorder. No significant association was found

Impact of aerobic exercise on sleep and motor skills in children with autism spectrum disorders – a pilot study

Directory of Open Access Journals (Sweden)

Br

2015-08-01

Full Text Available Serge Brand,1,2,* Stefanie Jossen,2,* Edith Holsboer-Trachsler,1 Uwe Pühse,2 Markus Gerber21Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders (ZASS, 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland*These authors contributed equally to this work and share the first authorshipBackground: Prevalence rates of autism spectrum disorder (ASD have increased dramatically in the last two decades. In addition to the core symptoms such as impaired communication, difficulties in social interaction, and restricted and stereotypical patterns of behavior and interests, poor sleep and motor skill (MS deficits have also been observed in children with ASD. On the other hand, there is evidence that aerobic exercise training (AET has a positive impact on sleep, and that specific training improves MSs. Accordingly, the aim of the present pilot study was to investigate to what extent a combination of AET and MS training (MST would improve sleep and physical performance in a small sample of children with ASD. Method: Ten children with ASD (mean age: 10 years took part in the study. After a thorough medical examination and psychiatric assessment, children participated in thrice-weekly 60-minute sessions of AET and MST lasting for 3 consecutive weeks. Sleep was assessed both objectively (sleep-encephalography [sleep-EEG] and subjectively (parents’ questionnaire. MSs were assessed via standardized test batteries. Parents completed sleep and mood logs, and ratings of mood. Results: Mild-to-moderate insomnia was reported in 70% of children. Compared to nights without previous AET and MS, on nights following AET and MS, sleep efficiency increased (d=1.07, sleep onset latency shortened (d=0.38, and wake time after sleep onset decreased for 63% of the sample (d=1.09, as assessed via sleep-EEG. Mood in the morning, as rated by parents, improved after three weeks (d=0

Exercise is medicine for patients with major depressive disorders : but only if the “pill” is taken!

Directory of Open Access Journals (Sweden)

Gerber M

2016-08-01

Full Text Available Markus Gerber,1 Edith Holsboer-Trachsler,2 Uwe Pühse,3 Serge Brand1,2 1Department of Sport, Exercise and Health, Division of Sport and Psychosocial Health, University of Basel, 2Center for Affective, Stress and Sleep Disorders, Psychiatric Clinics of the University of Basel, 3Department of Sport, Exercise and Health, Division of Sport and Health Pedagogy, University of Basel, Basel, Switzerland Abstract: Major depressive disorders (MDDs are a widespread and burdensome mental illness associated with a high comorbidity with other conditions and a significantly reduced life expectancy compared to the general population. Therefore, targeted actions are needed to improve physical health in people with MDDs, in addition to ongoing efforts to enhance psychological well-being. Meanwhile, the positive effects of exercise training on the treatment of MDDs are well documented, while compelling evidence exists that exercise interventions can improve cardiorespiratory fitness in clinically meaningful ways. On the flipside, the long-term effects of exercise therapy are still not well documented, and recent studies suggest that initial improvements in MDDs dissipate if regular exercise participation is discontinued after the end of interventions. A recent survey among Swiss psychiatric hospitals further shows that all institutions provide some form of physical activity and exercise program. However, only a limited number of patients participate in these programs, mainly because participation is voluntary and no particular efforts are undertaken to engage patients with the lowest physical activity levels. We argue that more systematic efforts are needed to fully exploit the potential of physical activity and exercise programs in psychiatric care. We also emphasize that initiating and maintaining regular physical activity among psychiatric patients is a major challenge because specific dysfunctional cognitive–emotional processes might interfere with their

Impact of lowering ski binding settings on the outcome of the self-release test of ski bindings among female recreational skiers

Directory of Open Access Journals (Sweden)

Posch M

2017-12-01

Full Text Available Markus Posch,1 Martin Burtscher,1 Alois Schranz,2 Katja Tecklenburg,2 Kenneth Helle,2 Gerhard Ruedl1 1Department of Sport Science, University of Innsbruck, Innsbruck, Austria; 2Medalp Sportclinic, Imst, Austria Background and purpose: The ability to successfully self-release the ski binding can prevent skiing-related injuries of the lower extremities. Failure of binding release associated with a knee injury is significantly higher among females compared to males. The International Standards Organization ISO 11088 standard for binding setting values allows a lowering by 15% upon request of the skier. Thus, the aim of this study was to evaluate the impact of lowered ski binding settings by 15% on the outcome of the self-release test among female recreational skiers. Materials and methods: In this randomized single-blinded study, a cohort of 20 females (24.5±2.7 years performed the self-release test in the laboratory thrice with each leg under two conditions: 1 with an actual ISO 11088 setting and 2 with a setting lowered by 15%. For each attempt, torques calculated via the force plate were normalized to torques measured by a binding adjustment system (relative release torque, RRT. Results: Among 240 trials in total, more females were significantly able to self-release their ski bindings with lowered binding settings when compared to their actual ISO settings (53% vs 9%, p<0.001. Thirteen females (65% were able to release their bindings at least once with both legs with lowered binding settings compared to only three females (15% with their actual binding settings (p<0.001. Mean RRT of all failure of binding release trials significantly differed between lowered and actual binding settings (58.6%±22.2% vs 50.5%±20.4%, p=0.003. Conclusion: Four times more females were able to self-release their ski bindings at least once with both legs with a 15% lowered binding setting compared to their normal ISO 11088 setting. The fact that the ISO standard

Comparison of injury incidences between football teams playing in different climatic regions

Directory of Open Access Journals (Sweden)

Orchard JW

2013-12-01

Full Text Available John W Orchard,1 Markus Waldén,2 Martin Hägglund,3 Jessica J Orchard,1 Ian Chivers,4 Hugh Seward,5 Jan Ekstrand21School of Public Health, University of Sydney, Sydney, NSW, Australia; 2Department of Medical and Health Sciences, Division of Community Medicine, Linköping University, Linköping, Sweden; 3Department of Medical and Health Sciences, Division of Physiotherapy, Linköping University, Linköping, Sweden; 4Native Seeds, Cheltenham, VIC, Australia; 5Australian Football League Medical Officers Association, Melbourne, VIC, AustraliaAbstract: Australian Football League (AFL teams in northern (warmer areas generally have higher rates of injury than those in southern (cooler areas. Conversely, in soccer (football in Europe, teams in northern (cooler areas have higher rates of injury than those in southern (warmer areas, with an exception being knee anterior cruciate ligament (ACL injuries, which are more common in the southern (warmer parts of Europe. This study examined relative injury incidence in the AFL comparing 9,477 injuries over 229,827 player-weeks from 1999–2012. There was a slightly higher injury incidence for teams from warmer parts of Australia (relative risk [RR] 1.05, 95% confidence interval [CI] 1.01–1.10 with quadriceps strains (RR 1.32, 95% CI 1.10–1.58, knee cartilage injuries (RR 1.42, 95% CI 1.16–1.74, and ankle sprains (RR 1.17, 95% CI 1.00–1.37 all being more likely in warmer region teams. Achilles injuries followed a reverse pattern, tending to be more common in cooler region teams (RR 0.70, 95% CI 0.47–1.03. In conclusion, common findings from the AFL and European soccer are that ankle sprains and ACL injuries are generally more likely in teams playing in warmer climate zones, whereas Achilles tendinopathy may be more likely in teams playing in cooler zones. These injuries may have climate or surface risk factors (possibly related to types and structure of grass and shoe-surface traction that are

Dosimetric analysis for photon and electron beams in Whole body irradiation; Analisis dosimetrico para haces de fotones y electrones en irradiacion corporal total

Energy Technology Data Exchange (ETDEWEB)

Hurtado G, M [Posgrado. Fisica Medica Radiologica. Universidad Nacional de Colombia, Bogota. Instituto Nacional de Cancerologia. Instituto Regional de Cancer de la Orinoquia. Hospital Regional de Villavicencio, Meta (Colombia)

1999-12-31

To initiate the Whole body irradiation as an alternative for the treatment of the hematological diseases, leukemia and assistant for the osseous marrow transplantation, it may be taken account the application of International Protocols about control and quality assurance. It is established the intercomparison by the different dosimetric methods: cylindrical ionization chambers and parallel plane, radiographic emulsion film, semiconductor diodes (Mosfet transistors) and TLD-100 thermoluminescent crystals, obtained measurements for 140 x 140 cm{sup 2} fields and large distances 340 cm respect conventional fields in Radiotherapy. The in vitro dosimetry was realized at the Universal Anthropomorphic puppet Alderson Rando basically with the cylindrical crystals (1 mm diameter) of TLD-100 lithium fluoride. It was obtained the dose value with a 0.6 cm{sup 3} cylindrical ionization chamber and the Farmer electrometer for Whole body irradiation (ICT) with photons for electrons and were obtained values with the Markus plane parallel camera. Knowing the dose rate value to the source-surface distance DFS= 80 cm, it was calibrated the crystals with the reference radiation beam of {sup 60} Co for obtaining the response curve: Dose vs. Tl lecture. It was characterized the 10 % of the total population for 300 crystals for applying the statistics corresponding. The luminescence curve obtained of Gaussian form was considered satisfactory by its stability during the pre-anneal lecture and anneal process, getting the main peak lecture at 300 Centigrade according to assigned parameters at lecture equipment TLD Harshaw model 4500. The results indicate the functional dependence with the distance DFS= 340 cm for the following depth PPD, the relations TMR and TPR, the TAR is not calculated by the increment of the dispersion in air. The penumbra increment indicates an increase of the radiation field respect of luminous field. The dispersion angle q{sub 1} respect at the field central axis

SU-D-213-02: Characterization of the Effect of a New Commercial Transmission Detector On Radiotherapy Beams

International Nuclear Information System (INIS)

Cheung, J; Morin, O

2015-01-01

Purpose: To evaluate the influence of a new commercial transmission detector on radiotherapy beams of various energies. Methods: A transmission detector designed for online treatment monitoring was characterized on a TrueBeam STx linear accelerator with 6MV, 6FFF, 10MV, and 10FFF beams. Measurements of beam characteristics including percentage depth doses (PDDs), inplane and crossplane off-axis profiles at different depths, transmission factors, and skin dose were acquired at field sizes of 3×3cm, 5×5m, 10×10cm, and 20×20cm at 100cm and 80cm source-to-surface distance (SSD). All measurements were taken with and without the transmission detector in the path of the beam. A CC04 chamber was used for all profile and transmission factor measurements. Skin dose was assessed at 100cm, 90cm, and 80cm SSD and using a variety of detectors (Roos and Markus parallel-plate chambers, and OSLD). Results: The PDDs showed small differences between the unperturbed and perturbed beams for both 100cm and 80cm SSD (≤4mm dmax difference and <1.2% average profile difference). The differences were larger for the flattened beams and at larger field sizes. The off-axis profiles showed similar trends. The penumbras looked similar with and without the transmission detector. Comparisons in the central 80% of the profile showed a maximum average (maximum) profile difference between all field sizes of 0.756% (1.535%) and 0.739% (3.682%) for 100cm and 80cm SSD, respectively. The average measured skin dose at 100cm (80cm) SSD for 10×10cm field size was <4% (<35%) dose increase for all energies. For 20×20cm field size, this value increased to <10% (≤45%). Conclusion: The transmission detector has minimal effect on the clinically relevant radiotherapy beams for IMRT and VMAT (field sizes 10×10cm and less). For larger field sizes, some perturbations are observable which would need to be assessed for clinical impact. The authors of this publication has research support from IBA Dosimetry

Comparative evaluation of 64-slice CT angiography and digital subtraction angiography in assessing the cervicocranial vasculature

Directory of Open Access Journals (Sweden)

Randolf Klingebiel

2008-08-01

Full Text Available Randolf Klingebiel1, Max Kentenich3, Hans-Christian Bauknecht3, Florian Masuhr2, Eberhard Siebert1, Markus Busch2, Georg Bohner11Department of Neuroradiology, 2Department of Neurology, 3Department of Radiology, Charité Universitary Medicine Berlin, GermanyBackground: Noninvasive 64-slice computed tomography angiography (64-MSCTA closely approximates conventional catheter angiography (DSA in terms of detail resolution. Objective: Retrospective evaluation of cervicocranial (cc 64-MSCTA in comparison with DSA in patients with presumptive cc vascular disorders.Material and methods: Twenty-four 64-MSCTA studies (32 mm detector width, slice thickness 0.5 mm, 120 kv, 150 mAs, pitch 0.75 of patients with presumptive cc vascular pathology (13 men, 11 women, mean age 38.3 ± 11.3 yrs, range 19–54 yrs were assessed in comparison with DSA studies without abnormal findings in age-matched patients (11 men, 13 women, mean age 39.7 ± 11.9 yrs, range 18–54 yrs. Study readings were performed in a blinded manner by two neuroradiologists with respect to image quality and assessibility of various cc vascular segments by using a five-point scale. Radiation exposure was calculated for 64-MSCTA.Results: Each reader assessed 384/528 different vessel segments (64-MSCTA/DSA. Superior image quality was attributed to DSA with respect to the C1 ICA–C6 ICA, A3 ACA, and P3 PCA segments as well the AICA and SCA. 64-MSCTA was scored superior for C7 ICA and V4 VA segments. A significantly increased number of nonassessable V2- and V3 VA segments in DSA studies was noted. The effective dose for 64-MSCTA amounted to 2.2 mSv.Conclusions: 64-MSCTA provides near-equivalent diagnostic information of the cc vasculature as compared with DSA. According to our results, DSA should be considered primarily when peripheral vessels (A3/P3 or ICA segments close to the skull base (C2-5 are of interest, such as in primary angiitis or stenoocclusive ICA disease, respectively.Keywords: CT

Effect of various physical parameters on surface and build-up dose for 15-MV X-rays

International Nuclear Information System (INIS)

Yadav, Girigesh; Yadav, R.S.; Kumar, Alok

2010-01-01

The purpose of this study was to find out the effect of various physical parameters on the skin and build-up doses of 15-MV photon beams. The effects of field dimensions, acrylic shadow tray, focus to-skin distance (FSD) on surface and buildup dose were determined for open, motorized 60 deg wedge (MW) and blocked fields. A 'Markus' plane parallel plate chamber was used for these measurements in an Elekta (6-15MV) linear accelerator. The surface dose for MW fields was lower than the dose for an open field, but the trend reversed for large fields and higher degree wedges. With the use of an acrylic shadow tray, the surface dose increased for all field sizes, but the increase was dominant for large fields. The surface dose for blocked fields was lower than the dose for open fields. The percentage depth dose of 10 x 10 cm 2 field at surface (PDD 0 ) for open beam were 13.89%, 11.71%, and 10.74% at 80 cm, 100 cm, and 120 cm FSD, respectively. The blocking tray increased PDD 0 of 10 x 10 cm 2 field to 26.29%, 14.01%, and 11.53%, while the motorized 60 deg wedge decreased PDD 0 to 11.32%, 9.7%, and 8.9 % at these FSDs. The maximum PDD difference seen at surface (i.e. skin) for 5x5 cm 2 , 15x15 cm 2 , and 30x30 cm 2 are 0.5%, 4.6%, and 5.6% for open field and 0.9%, 4.7%, and 7.2% for motorized 60 deg wedge field, when FSDs varied from 80 cm to 120 cm. The maximum PDD difference seen at surface for 5x5 cm 2 , 15x15 cm 2 , and 30x30 cm 2 fields are 5.6%, 22.8%, and 29.6%, respectively, for a 1.0-cm perspex-blocking tray as the FSD is changed. The maximum PDD difference was seen at the surface (i.e. skin) and this decreased with increasing depth. (author)

Dosimetric analysis for photon and electron beams in Whole body irradiation

International Nuclear Information System (INIS)

Hurtado G, M.

1998-01-01

To initiate the Whole body irradiation as an alternative for the treatment of the hematological diseases, leukemia and assistant for the osseous marrow transplantation, it may be taken account the application of International Protocols about control and quality assurance. It is established the intercomparison by the different dosimetric methods: cylindrical ionization chambers and parallel plane, radiographic emulsion film, semiconductor diodes (Mosfet transistors) and TLD-100 thermoluminescent crystals, obtained measurements for 140 x 140 cm 2 fields and large distances 340 cm respect conventional fields in Radiotherapy. The in vitro dosimetry was realized at the Universal Anthropomorphic puppet Alderson Rando basically with the cylindrical crystals (1 mm diameter) of TLD-100 lithium fluoride. It was obtained the dose value with a 0.6 cm 3 cylindrical ionization chamber and the Farmer electrometer for Whole body irradiation (ICT) with photons for electrons and were obtained values with the Markus plane parallel camera. Knowing the dose rate value to the source-surface distance DFS= 80 cm, it was calibrated the crystals with the reference radiation beam of 60 Co for obtaining the response curve: Dose vs. Tl lecture. It was characterized the 10 % of the total population for 300 crystals for applying the statistics corresponding. The luminescence curve obtained of Gaussian form was considered satisfactory by its stability during the pre-anneal lecture and anneal process, getting the main peak lecture at 300 Centigrade according to assigned parameters at lecture equipment TLD Harshaw model 4500. The results indicate the functional dependence with the distance DFS= 340 cm for the following depth PPD, the relations TMR and TPR, the TAR is not calculated by the increment of the dispersion in air. The penumbra increment indicates an increase of the radiation field respect of luminous field. The dispersion angle q 1 respect at the field central axis was determined and was

Dosimetric analysis for photon and electron beams in Whole body irradiation; Analisis dosimetrico para haces de fotones y electrones en irradiacion corporal total

Energy Technology Data Exchange (ETDEWEB)

Hurtado G, M. [Posgrado. Fisica Medica Radiologica. Universidad Nacional de Colombia, Bogota. Instituto Nacional de Cancerologia. Instituto Regional de Cancer de la Orinoquia. Hospital Regional de Villavicencio, Meta (Colombia)

1998-12-31

To initiate the Whole body irradiation as an alternative for the treatment of the hematological diseases, leukemia and assistant for the osseous marrow transplantation, it may be taken account the application of International Protocols about control and quality assurance. It is established the intercomparison by the different dosimetric methods: cylindrical ionization chambers and parallel plane, radiographic emulsion film, semiconductor diodes (Mosfet transistors) and TLD-100 thermoluminescent crystals, obtained measurements for 140 x 140 cm{sup 2} fields and large distances 340 cm respect conventional fields in Radiotherapy. The in vitro dosimetry was realized at the Universal Anthropomorphic puppet Alderson Rando basically with the cylindrical crystals (1 mm diameter) of TLD-100 lithium fluoride. It was obtained the dose value with a 0.6 cm{sup 3} cylindrical ionization chamber and the Farmer electrometer for Whole body irradiation (ICT) with photons for electrons and were obtained values with the Markus plane parallel camera. Knowing the dose rate value to the source-surface distance DFS= 80 cm, it was calibrated the crystals with the reference radiation beam of {sup 60} Co for obtaining the response curve: Dose vs. Tl lecture. It was characterized the 10 % of the total population for 300 crystals for applying the statistics corresponding. The luminescence curve obtained of Gaussian form was considered satisfactory by its stability during the pre-anneal lecture and anneal process, getting the main peak lecture at 300 Centigrade according to assigned parameters at lecture equipment TLD Harshaw model 4500. The results indicate the functional dependence with the distance DFS= 340 cm for the following depth PPD, the relations TMR and TPR, the TAR is not calculated by the increment of the dispersion in air. The penumbra increment indicates an increase of the radiation field respect of luminous field. The dispersion angle q{sub 1} respect at the field central axis

Lung vital capacity and oxygen saturation in adults with cerebral palsy

Directory of Open Access Journals (Sweden)

Lampe R

2014-12-01

Full Text Available Renée Lampe,1,2 Tobias Blumenstein,2 Varvara Turova,2 Ana Alves-Pinto2 1Markus Würth Stiftungsprofessur, Technical University of Munich, Munich, Germany; 2Research Unit for Cerebral Palsy and Children Neuroorthopaedics of the Buhl-Strohmaier Foundation, Orthopedic Department of the Clinic “rechts der Isar” of the Technical University of Munich, Munich, Germany Background: Individuals with infantile cerebral palsy have multiple disabilities. The most conspicuous syndrome being investigated from many aspects is motor movement disorder with a spastic gait pattern. The lung function of adults with spasticity attracts less attention in the literature. This is surprising because decreased thoracic mobility and longstanding scoliosis should have an impact on lung function. With increasing age and the level of disability, individuals become susceptible to lung infections and reflux illness, and these are accompanied by increased aspiration risk. This study examined, with different methods, to what extent adults with congenital cerebral palsy and acquired spastic paresis – following traumatic brain injury – showed restriction of lung function. It also assessed the contribution of disability level on this restriction.Methods: The oxygen saturation of 46 adults with a diagnosis of cerebral palsy was measured with an oximeter. Lung vital capacity was measured with a mobile spirometer and excursion of the thorax was clinically registered. The gross motor function levels and the presence or absence of scoliosis were determined.Results: A significantly positive correlation between lung vital capacity and chest expansion was established. Both the lung vital capacity and the thorax excursion decreased with increases in gross motor function level. Oxygen saturation remained within the normal range in all persons, in spite of reduced values of the measured lung parameters. No statistically significant dependency between lung vital capacity and oxygen

Effect of hepatitis C virus on the central nervous system of HIV-infected individuals

Directory of Open Access Journals (Sweden)

Forton D

2012-11-01

Full Text Available Markus Gess, Daniel FortonDepartment of Gastroenterology and Hepatology, St George’s University of London, London, UKAbstract: Infection with the human immunodeficiency virus (HIV is associated with a spectrum of neuropsychiatric manifestations ranging from asymptomatic cognitive impairment, detectable only by sensitive neurocognitive tests, to overt HIV-associated dementia. Highly active antiretroviral therapy has led to significant reductions in the incidence of severe HIV-associated dementia. However, the overall prevalence of milder HIV-associated cognitive disorders appears to be increasing as HIV-infected subjects live longer in the era of combined antiretroviral treatments. Chronic hepatitis C virus (HCV infection is also associated with neuropsychological symptoms and impaired cognitive performance in some patients, and recent evidence suggests that these central nervous system (CNS symptoms may be caused by HCV entry into the brain via endothelial infection. Similarly to the neuropathological processes in HIV infection, microglial activation in HCV infected subjects may underlie the CNS metabolic abnormalities and impaired cognitive performance that have been described in studies of HCV-infected cohorts. A significant proportion of HIV-infected subjects are coinfected with HCV, but the impact and clinical importance of coinfection on cognitive function has only been addressed in a small number of research studies. There is some evidence that coinfection may adversely affect neurocognitive function; however, studies published thus far are limited by a number of confounding factors and small sample sizes. This article aims to review the current evidence examining neurocognitive function in HIV- and HCV-monoinfection and further critically discusses previous studies that have explored the impact of coinfection with HCV on CNS function of HIV-infected cohorts. It is clear that, as the population of HIV-infected individuals ages and

WE-D-BRE-01: A Sr-90 Irradiation Device for the Study of Cutaneous Radiation Injury

Energy Technology Data Exchange (ETDEWEB)

Dorand, JE; Bourland, JD [Department of Radiation Oncology and Department of Physics, Wake Forest University, Winston-Salem, NC (United States); Burnett, LR [KeraNetics, LLC, Winston-Salem, NC (United States); Tytell, M [Department of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, NC (United States)

2014-06-15

Purpose: To determine dosimetric character for a custom-built Sr-90 beta irradiator designed for the study of Cutaneous Radiation Injury (CRI) in a porcine animal model. In the event of a radiological accident or terrorist event, Sr-90, a fission by-product, will likely be produced. CRI is a main concern due to the low energy and superficial penetration in tissue of beta particles from Sr-90. Seven 100 mCi plaque Sr-90 radiation sources within a custom-built irradiation device create a 40 mm diameter region of radiation-induced skin injury as part of a larger project to study the efficacy of a topical keratin-based product in CRI healing. Methods: A custom-built mobile irradiation device was designed and implemented for in vivo irradiations. Gafchromic™ EBT3 radiochromic film and a PTW Markus chamber type 23343 were utilized for dosimetric characterization of the beta fluence at the surface produced by this device. Films were used to assess 2-dimensional dose distribution and percent depth dose characteristics of the radiation field. Ion chamber measurements provided dose rate data within the field. Results: The radiation field produced by the irradiation device is homogeneous with high uniformity (∼5%) and symmetry (∼3%) with a steep dose fall-off with depth from the surface. Dose rates were determined to be 3.8 Gy/min and 3.3 Gy/min for film and ion chamber measurements, respectively. A dose rate of 3.4 Gy/min was used to calculate irradiation times for in vivo irradiations. Conclusion: The custom-built irradiation device enables the use of seven Sr-90 beta sources in an array to deliver a 40 mm diameter area of homogeneous skin dose with a dose rate that is useful for research purposes and clinically relevant for the induction of CRI. Doses of 36 and 42 Gy successfully produce Grade III CRI and are used in the study of the efficacy of KeraStat™. This project has been funded in whole or in part with Federal funds from the Biomedical Advanced Research and

SU-C-201-03: Ionization Chamber Collection Efficiency in Pulsed Radiation Fields of High Pulse Dose

Energy Technology Data Exchange (ETDEWEB)

Gotz, M; Karsch, L [Oncoray - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universitaet Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden (Germany); Pawelke, J [Oncoray - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universitaet Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden (Germany); Helmholtz-Zentrum Dresden - Rossendorf, Dresden (Germany)

2016-06-15

Purpose: To investigate the reduction of collection efficiency of ionization chambers (IC) by volume recombination and its correction in pulsed fields of very high pulse dose. Methods: Measurements of the collection efficiency of a plane-parallel advanced Markus IC (PTW 34045, 1mm electrode spacing, 300V nominal voltage) were obtained for collection voltages of 100V and 300V by irradiation with a pulsed electron beam (20MeV) of varied pulse dose up to approximately 600mGy (0.8nC liberated charge). A reference measurement was performed with a Faraday cup behind the chamber. It was calibrated for the liberated charge in the IC by a linear fit of IC measurement to reference measurement at low pulse doses. The results were compared to the commonly used two voltage approximation (TVA) and to established theories for volume recombination, with and without considering a fraction of free electrons. In addition, an equation system describing the charge transport and reactions in the chamber was solved numerically. Results: At 100V collection voltage and moderate pulse doses the established theories accurately predict the observed collection efficiency, but at extreme pulse doses a fraction of free electrons needs to be considered. At 300V the observed collection efficiency deviates distinctly from that predicted by any of the established theories, even at low pulse doses. However, the numeric solution of the equation system is able to reproduce the measured collection efficiency across the entire dose range of both voltages with a single set of parameters. Conclusion: At high electric fields (3000V/cm here) the existing theoretical descriptions of collection efficiency, including the TVA, are inadequate to predict pulse dose dependency. Even at low pulse doses they might underestimate collection efficiency. The presented, more accurate numeric solution, which considers additional effects like electric shielding by the charges, might provide a valuable tool for future

Demands and Needs for Psycho-Oncological eHealth Interventions in Women With Cancer: Cross-Sectional Study.

Science.gov (United States)

Ringwald, Johanna; Marwedel, Lennart; Junne, Florian; Ziser, Katrin; Schäffeler, Norbert; Gerstner, Lena; Wallwiener, Markus; Brucker, Sara Yvonne; Hautzinger, Martin; Zipfel, Stephan; Teufel, Martin

2017-11-24

promising medium to improve the psychosocial care and enhance individual disease management and engagement among women with cancer. ©Johanna Ringwald, Lennart Marwedel, Florian Junne, Katrin Ziser, Norbert Schäffeler, Lena Gerstner, Markus Wallwiener, Sara Yvonne Brucker, Martin Hautzinger, Stephan Zipfel, Martin Teufel. Originally published in JMIR Cancer (http://cancer.jmir.org), 24.11.2017.

Dosimetric commissioning and quality assurance of scanned ion beams at the Italian National Center for Oncological Hadrontherapy

Energy Technology Data Exchange (ETDEWEB)

Mirandola, Alfredo, E-mail: mirandola@cnao.it; Molinelli, S.; Vilches Freixas, G.; Mairani, A.; Gallio, E.; Panizza, D.; Russo, S.; Ciocca, M. [Fondazione CNAO, strada Campeggi 53, Pavia 27100 (Italy); Donetti, M. [INFN, Torino 10125, Italy and Fondazione CNAO, strada Campeggi 53, Pavia 27100 (Italy); Magro, G. [INFN–Dipartimento di Fisica, Università degli Studi di Pavia, Via U. Bassi 6, Pavia 27100, Italy and Fondazione CNAO, strada Campeggi 53, Pavia 27100 (Italy); Giordanengo, S. [INFN, Torino 10125 (Italy); Orecchia, R. [Fondazione CNAO, strada Campeggi 53, Pavia 27100, Italy and Radiotherapy Division, European Institute of Oncology, Via Ripamonti 435, Milano 20141 (Italy)

2015-09-15

Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated depth-dose-distributions (IDDs) were acquired with the PTW Peakfinder, a variable depth water column, equipped with two Bragg peak ionization chambers. FLUKA Monte Carlo code was used to generate the energy libraries, the IDDs in water, and the fragment spectra for carbon beams. EBT3 films were used for spot size measurements, beam position over the scan field, and homogeneity in 2D-fields. Beam monitor calibration was performed in terms of number of particles per monitor unit using both a Farmer-type and an Advanced Markus ionization chamber. The beam position at the isocenter, beam monitor calibration curve, dose constancy in the center of the spread-out-Bragg-peak, dose homogeneity in 2D-fields, beam energy, spot size, and spot position over the scan field are all checked on a daily basis for both protons and carbon ions and on all beam lines. Results: The simulated IDDs showed an excellent agreement with the measured experimental curves. The measured full width at half maximum (FWHM) of the pencil beam in air at the isocenter was energy-dependent for both particle species: in particular, for protons, the spot size ranged from 0.7 to 2.2 cm. For carbon ions, two sets of spot size are available: FWHM ranged from 0.4 to 0.8 cm (for the smaller spot size) and from 0.8 to 1.1 cm (for the larger one). The spot position was accurate to within ±1 mm over the whole 20 × 20 cm{sup 2} scan field; homogeneity in a uniform squared field was within ±5% for both particle types at any energy. QA results exceeding tolerance levels were rarely found. In the reporting period, the machine downtime was around 6%, of which 4.5% was due to planned maintenance shutdowns. Conclusions: After successful dosimetric beam commissioning, quality assurance measurements

Dosimetric commissioning and quality assurance of scanned ion beams at the Italian National Center for Oncological Hadrontherapy

International Nuclear Information System (INIS)

Mirandola, Alfredo; Molinelli, S.; Vilches Freixas, G.; Mairani, A.; Gallio, E.; Panizza, D.; Russo, S.; Ciocca, M.; Donetti, M.; Magro, G.; Giordanengo, S.; Orecchia, R.

2015-01-01

Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated depth-dose-distributions (IDDs) were acquired with the PTW Peakfinder, a variable depth water column, equipped with two Bragg peak ionization chambers. FLUKA Monte Carlo code was used to generate the energy libraries, the IDDs in water, and the fragment spectra for carbon beams. EBT3 films were used for spot size measurements, beam position over the scan field, and homogeneity in 2D-fields. Beam monitor calibration was performed in terms of number of particles per monitor unit using both a Farmer-type and an Advanced Markus ionization chamber. The beam position at the isocenter, beam monitor calibration curve, dose constancy in the center of the spread-out-Bragg-peak, dose homogeneity in 2D-fields, beam energy, spot size, and spot position over the scan field are all checked on a daily basis for both protons and carbon ions and on all beam lines. Results: The simulated IDDs showed an excellent agreement with the measured experimental curves. The measured full width at half maximum (FWHM) of the pencil beam in air at the isocenter was energy-dependent for both particle species: in particular, for protons, the spot size ranged from 0.7 to 2.2 cm. For carbon ions, two sets of spot size are available: FWHM ranged from 0.4 to 0.8 cm (for the smaller spot size) and from 0.8 to 1.1 cm (for the larger one). The spot position was accurate to within ±1 mm over the whole 20 × 20 cm"2 scan field; homogeneity in a uniform squared field was within ±5% for both particle types at any energy. QA results exceeding tolerance levels were rarely found. In the reporting period, the machine downtime was around 6%, of which 4.5% was due to planned maintenance shutdowns. Conclusions: After successful dosimetric beam commissioning, quality assurance measurements

National choices in a European perspective. Proceedings of the European Forum 2003

International Nuclear Information System (INIS)

Sido, Bruno; Lamoureux, Francois; ); Herzog, Philippe; ); Barre, Bertrand; Bataille, Christian; Colombani, Pascal; Gonzalez Gomez, Jose Luis; Lescoeur, DBruno; Perez, Serge; Weh, Rudolf; Westerlind, Magnus; Houssin, Didier; Nagashima, Hideo; Pavlopoulos, Panagiotis; Linkohr, Rolf; ); Allemeersch, Antoine; Beveridge, George; Bonnemains, Jacky; Fritschi, Markus; Piguet, Jack-Pierre; Rigny, Paul; Streydio, Jean-Marie; Tallec, Michele; Vasa, Ivo; Pancher, Bertrand

2003-01-01

from: Antoine Allemeersch, Mayor, Cirfontaines en Ornois, George Beveridge, Director, BNFL Environmental services (UK), Jacky Bonnemains, President, Robin des Bois, Markus Fritschi, Director, NAGRA (Switzerland), Jack-Pierre Piguet, Director Meuse/Haute-Marne Laboratory (ANDRA), Paul Rigny, scientific adviser, Jean-Marie Streydio, Chairman, ONDRAF (Belgium), Michele Tallec, developpement/innovation (CEA), Ivo Vasa, Head, Nuclear Safety and Security Department, Czech nuclear research Institute, member of RAWRA, 8 - Conclusions and propositions for the European public talks 2004 by Bertrand Pancher, Chairman of the County Council of Meuse

REVIEW: TRANSCULTURAL ENCOUNTERS IN THE HIMALAYAN BORDERLANDS - KALIMPONG AS A "CONTACT ZONE"

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Reviewed by Enrico Beltramini

2018-05-01

Full Text Available Markus Viehbeck (ed., 2017. Transcultural Encounters in the Himalayan Borderlands - Kalimpong as a "Contact Zone." Heidelberg: Heidelberg University Publishing, viii + 350 pp, ISBN 978-3-946054-58-0 (paperback 55.37USD. This volume is both a story of the hill station of Kalimpong, in the Eastern Himalayan region, and a study of transcultural dynamics seen through the prism of the local story of Kalimpong. A collaborative work, the book is the result of a conference that brought together various international scholars on the cultural history of Kalimpong. Scholars from Europe (Amsterdam, Copenhagen, Heidelberg, Manchester, Oxford, Roskilde, North America (Los Angeles, Toronto, Oceania (Melbourne, and India (Sikkim met in Kalimpong 6-8 March 2015, to discuss the topic from a variety of disciplinary viewpoints, including social history, Tibetan studies, anthropology, ethnography, religious studies, and postcolonial literature. The publisher, Heidelberg University Publishing, has included this anthology in its prestigious Heidelberg Studies on Transculturality. The history of Kalimpong, the other mountain town of Darjeeling and, more generally the entire Eastern Himalayan region, has been the focus of a specialized yet expanding scholarly field. Works center on Kalimpong (Hilker, 2005, Darjeeling (Besky, 2014; Sharma, 2011 and 2014; Warner, 2014, and the entire area of the Himalayan territories of Nepal, Sikkim, and Bhutan, as well as parts of Northern-Eastern India (Huber and Blackburn, 2012; McKay, 2007; Mullard, 2011; Phuntsho, 2013; Shneiderman, 2015. In this context, scholars note how Kalimpong and Darjeeling shared the same destiny: originally sparsely populated settlements in the foothills of the Himalayas, both villages were acquired in the nineteenth century by the English East India Company (Kalimpong was annexed in 1865 from the kingdom of Bhutan, and Darjeeling from the kingdom of Sikkim in 1835 to become British-ruled towns and

SU-C-201-03: Ionization Chamber Collection Efficiency in Pulsed Radiation Fields of High Pulse Dose

International Nuclear Information System (INIS)

Gotz, M; Karsch, L; Pawelke, J

2016-01-01

Purpose: To investigate the reduction of collection efficiency of ionization chambers (IC) by volume recombination and its correction in pulsed fields of very high pulse dose. Methods: Measurements of the collection efficiency of a plane-parallel advanced Markus IC (PTW 34045, 1mm electrode spacing, 300V nominal voltage) were obtained for collection voltages of 100V and 300V by irradiation with a pulsed electron beam (20MeV) of varied pulse dose up to approximately 600mGy (0.8nC liberated charge). A reference measurement was performed with a Faraday cup behind the chamber. It was calibrated for the liberated charge in the IC by a linear fit of IC measurement to reference measurement at low pulse doses. The results were compared to the commonly used two voltage approximation (TVA) and to established theories for volume recombination, with and without considering a fraction of free electrons. In addition, an equation system describing the charge transport and reactions in the chamber was solved numerically. Results: At 100V collection voltage and moderate pulse doses the established theories accurately predict the observed collection efficiency, but at extreme pulse doses a fraction of free electrons needs to be considered. At 300V the observed collection efficiency deviates distinctly from that predicted by any of the established theories, even at low pulse doses. However, the numeric solution of the equation system is able to reproduce the measured collection efficiency across the entire dose range of both voltages with a single set of parameters. Conclusion: At high electric fields (3000V/cm here) the existing theoretical descriptions of collection efficiency, including the TVA, are inadequate to predict pulse dose dependency. Even at low pulse doses they might underestimate collection efficiency. The presented, more accurate numeric solution, which considers additional effects like electric shielding by the charges, might provide a valuable tool for future

SU-D-213-02: Characterization of the Effect of a New Commercial Transmission Detector On Radiotherapy Beams

Energy Technology Data Exchange (ETDEWEB)

Cheung, J; Morin, O [University of California San Francisco, San Francisco, CA (United States)

2015-06-15

Purpose: To evaluate the influence of a new commercial transmission detector on radiotherapy beams of various energies. Methods: A transmission detector designed for online treatment monitoring was characterized on a TrueBeam STx linear accelerator with 6MV, 6FFF, 10MV, and 10FFF beams. Measurements of beam characteristics including percentage depth doses (PDDs), inplane and crossplane off-axis profiles at different depths, transmission factors, and skin dose were acquired at field sizes of 3×3cm, 5×5m, 10×10cm, and 20×20cm at 100cm and 80cm source-to-surface distance (SSD). All measurements were taken with and without the transmission detector in the path of the beam. A CC04 chamber was used for all profile and transmission factor measurements. Skin dose was assessed at 100cm, 90cm, and 80cm SSD and using a variety of detectors (Roos and Markus parallel-plate chambers, and OSLD). Results: The PDDs showed small differences between the unperturbed and perturbed beams for both 100cm and 80cm SSD (≤4mm dmax difference and <1.2% average profile difference). The differences were larger for the flattened beams and at larger field sizes. The off-axis profiles showed similar trends. The penumbras looked similar with and without the transmission detector. Comparisons in the central 80% of the profile showed a maximum average (maximum) profile difference between all field sizes of 0.756% (1.535%) and 0.739% (3.682%) for 100cm and 80cm SSD, respectively. The average measured skin dose at 100cm (80cm) SSD for 10×10cm field size was <4% (<35%) dose increase for all energies. For 20×20cm field size, this value increased to <10% (≤45%). Conclusion: The transmission detector has minimal effect on the clinically relevant radiotherapy beams for IMRT and VMAT (field sizes 10×10cm and less). For larger field sizes, some perturbations are observable which would need to be assessed for clinical impact. The authors of this publication has research support from IBA Dosimetry.

Tramadol/paracetamol combination tablet for postoperative pain following ambulatory hand surgery: a double-blind, double-dummy, randomized, parallel-group trial

Directory of Open Access Journals (Sweden)

Rawal N

2011-04-01

Full Text Available Narinder Rawal1, Valery Macquaire2, Elena Catalá3, Marco Berti4, Rui Costa5, Markus Wietlisbach61Department of Anesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden; 2Clinique du Parc Leopold, Brussels, Belgium; 3Pain Clinic, Department Anesthesiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 4Department of Anesthesiology and Reanimation, Parma Hospital, Parma, Italy; 5Garcia de Orta Hospital, Almada, Portugal; 6Department of Anesthesiology, Sursee Hospital, Sursee, SwitzerlandAbstract: This randomized, double-blind, double-dummy, multicenter trial compared efficacy and safety of tramadol HCL 37.5 mg/paracetamol 325 mg combination tablet with tramadol HCL 50 mg capsule in the treatment of postoperative pain following ambulatory hand surgery with iv regional anesthesia. Patients received trial medication at admission, immediately after surgery, and every 6 hours after discharge until midnight of the first postoperative day. Analgesic efficacy was assessed by patients (n = 128 in each group, full analysis set and recorded in a diary on the evening of surgery day and of the first postoperative day. They also documented the occurrence of adverse events. By the end of the first postoperative day, the proportion of treatment responders based on treatment satisfaction (primary efficacy variable was comparable between the groups (78.1% combination, 71.9% tramadol; P = 0.24 and mean pain intensity (rated on a numerical scale from 0 = no pain to 10 = worst imaginable pain had been reduced to 1.7 ± 2.0 for both groups. Under both treatments, twice as many patients experienced no pain (score = 0 on the first postoperative day compared to the day of surgery (35.9% vs 16.4% for tramadol/paracetamol and 36.7% vs 18% for tramadol treatment. Rescue medication leading to withdrawal (diclofenac 50 mg was required by 17.2% patients with tramadol/paracetamol and 13.3% with tramadol. Adverse events (mainly nausea, dizziness

The Role of the Photogeologic Mapping in the Morocco 2013 Mars Analog Field Simulation (Austrian Space Forum)

Science.gov (United States)

Losiak, Anna; Orgel, Csilla; Moser, Linda; MacArthur, Jane; Gołębiowska, Izabela; Wittek, Steffen; Boyd, Andrea; Achorner, Isabella; Rampey, Mike; Bartenstein, Thomas; Jones, Natalie; Luger, Ulrich; Sans, Alejandra; Hettrich, Sebastian

2013-04-01

choosing the best alternative traverses if the ones suggested by the flight planning team based on satellite data turn out to be impossible. The set of maps includes: A "geological map" prepared following suggestions of [3]. A set of experiment "suitability maps", one for every experiment, assessing the suitability of the area for an experiment. E.g., if a rover cannot move on surfaces that have an inclination larger than 5° and/or are covered with rocks larger than 15 cm in diameter, than the areas likely to have such conditions will be marked as not suitable for this experiment. "Danger" map - showing locations of all potentially dangerous places e.g., cliffs. "Mobility" map - with information important for estimating astronauts' mobility. During the mission maps will be updated on a daily basis, based on the observations made in the field. In this way quality of the maps (and predictions based on them) will be gradually improved. Acknowledges: We thank all people involved in the MARS2013 mission, especially Dr. Gernot Grömer, the President of Austrian Space Forum, MARS2013 program officer & expedition lead. References: [1] Sans Fuentes S.A. 2012. Human-Robotic Mars Science Operations: Target Selection Optimization via Traverse and Science Planning. (M.S. thesis). U. of Innsbruck. [2] Hettich S. 2012. Human-Robotic Mars Science Operations: Itinerary Optimisation for Surface Activities (M.S. thesis). U. of Innsbruck. [3] Skinner J.A.Jr., Fortezzo C.M. 2011. Acta Astronautica. http://dx.doi.org/10.1016/j.actaastro.2011.11.011.

Les peintures murales de l’église de Mălâncrav. Notes avant la restauration

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Dana Jenei

2015-12-01

Full Text Available The two distinct ensembles of mural paintings of the church, from the nave and sanctuary have permanently been in the attention of the researchers, but their study cannot be considered completed, because thorough parament studies and archaeological investigations, indispensable to clarify the phases of the monument, have not yet been achieved. However, the research works in the years 2001-2002 and 2013 brought to light new data that substantially enrich the information and contribute to a better understanding of the evolution of the monument. In 2001, the investigations showed, among others, that except the frescoes on the north, there are no other painted zones inside the nave, while in 2013 the restorers have revealed the existence of the register VI of paintings on the pillars, which mostly are under the lime. The art historian’s research contributes with the identification of several scenes and details unknown so far, such as the figures of Saints James, Sebastian, Anthony and Peter, or the jesters next to Herod and Pilate in the Christological Cycle. There was also detected the contribution of three distinct teams who have worked, “soon after 1350”. The paintings in the nave illustrate, along with the ensemble in the sanctuary, the various artistic trends subsumed to the Gothic painting from the fourteenth century and due to the munificence of successive generations of the noble family Apa, lords at Mălâncrav since 1258. The graffiti on the painted surface of the apse, transcribed by Victor Roth in several versions, contains the year 1404/1405, considered as a terminus ante quem for the achievement of the painting, and the name Nicolaus, the most important representative of the family and the presumptive donor of the paintings. Gernot Nussbächer “shows” that the inscription is not of “Hic fuit” type and the script is a few decades later, presumably recording an event that took place that year. The obvious difference of the

Transient elastography with the XL probe rapidly identifies patients with nonhepatic ascites

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Mueller S

2012-05-01

Full Text Available Anna Kohlhaas1, Esteban Durango1, Gunda Millonig1, Cecile Bastard2, Laurent Sandrin2, Mohammad Golriz3, Arianeb Mehrabi3, Markus W Büchler3, Helmut Karl Seitz1, Sebastian Mueller11Department of Medicine and Center for Alcohol Research, Liver Disease and Nutrition, Salem Medical Center, University of Heidelberg, Heidelberg, Germany; 2Department of Research and Development, Echosens, Paris, France; 3Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, GermanyBackground: In contrast with other elastographic techniques, ascites is considered an exclusion criterion for assessment of fibrosis stage by transient elastography. However, a normal liver stiffness could rule out hepatic causes of ascites at an early stage. The aim of the present study was to determine whether liver stiffness can be generally determined by transient elastography through an ascites layer, to determine whether the ascites-mediated increase in intra-abdominal pressure affects liver stiffness, and to provide initial data from a pilot cohort of patients with various causes of ascites.Methods and results: Using the XL probe in an artificial ascites model, we demonstrated (copolymer phantoms surrounded by water that a transient elastography-generated shear wave allows accurate determination of phantom stiffness up to a water lamella of 20 mm. We next showed in an animal ascites model that increased intra-abdominal pressure does not affect liver stiffness. Liver stiffness was then determined in 24 consecutive patients with ascites due to hepatic (n = 18 or nonhepatic (n = 6 causes. The cause of ascites was eventually clarified using routine clinical, imaging, laboratory, and other tools. Valid (75% or acceptable (25% liver stiffness data could be obtained in 23 patients (95.8% with ascites up to an ascites lamella of 39 mm. The six patients (25% with nonhepatic causes of ascites (eg, pancreatitis, peritoneal carcinomatosis had a

Peyton’s four-step approach: differential effects of single instructional steps on procedural and memory performance – a clarification study

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Krautter M

2015-05-01

Full Text Available Markus Krautter,1 Ronja Dittrich,2 Annette Safi,2 Justine Krautter,1 Imad Maatouk,2 Andreas Moeltner,2 Wolfgang Herzog,2 Christoph Nikendei2 1Department of Nephrology, 2Department of General Internal and Psychosomatic Medicine, University of Heidelberg Medical Hospital, Heidelberg, Germany Background: Although Peyton’s four-step approach is a widely used method for skills-lab training in undergraduate medical education and has been shown to be more effective than standard instruction, it is unclear whether its superiority can be attributed to a specific single step. Purpose: We conducted a randomized controlled trial to investigate the differential learning outcomes of the separate steps of Peyton’s four-step approach. Methods: Volunteer medical students were randomly assigned to four different groups. Step-1 group received Peyton’s Step 1, Step-2 group received Peyton’s Steps 1 and 2, Step-3 group received Peyton’s Steps 1, 2, and 3, and Step-3mod group received Peyton’s Steps 1 and 2, followed by a repetition of Step 2. Following the training, the first independent performance of a central venous catheter (CVC insertion using a manikin was video-recorded and scored by independent video assessors using binary checklists. The day after the training, memory performance during delayed recall was assessed with an incidental free recall test. Results: A total of 97 participants agreed to participate in the trial. There were no statistically significant group differences with regard to age, sex, completed education in a medical profession, completed medical clerkships, preliminary memory tests, or self-efficacy ratings. Regarding checklist ratings, Step-2 group showed a superior first independent performance of CVC placement compared to Step-1 group (P<0.001, and Step-3 group showed a superior performance to Step-2 group (P<0.009, while Step-2 group and Step-3mod group did not differ (P=0.055. The findings were similar in the incidental

Perceptions of Patient Engagement Applications During Pregnancy: A Qualitative Assessment of the Patient's Perspective.

Science.gov (United States)

Goetz, Maren; Müller, Mitho; Matthies, Lina Maria; Hansen, Jenny; Doster, Anne; Szabo, Akos; Pauluschke-Fröhlich, Jan; Abele, Harald; Sohn, Christof; Wallwiener, Markus; Wallwiener, Stephanie

2017-05-26

highly frequented source of information. Expectations and usability requirements for those applications are also high, thus posing a challenge to interdisciplinary service providers. Patients' attitude toward integrating apps in routine care settings was positive with a favorable influence on patient empowerment. Health care professionals should guide pregnant women toward a successful integration of these educational tools in pregnancy care. ©Maren Goetz, Mitho Müller, Lina Maria Matthies, Jenny Hansen, Anne Doster, Akos Szabo, Jan Pauluschke-Fröhlich, Harald Abele, Christof Sohn, Markus Wallwiener, Stephanie Wallwiener. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 26.05.2017.

Green synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng

Directory of Open Access Journals (Sweden)

Abbai R

2016-07-01

Full Text Available Ragavendran Abbai,1,* Ramya Mathiyalagan,1,* Josua Markus,1 Yeon-Ju Kim,2 Chao Wang,2 Priyanka Singh,2 Sungeun Ahn,2 Mohamed El-Agamy Farh,2 Deok Chun Yang1,2 1Ginseng Bank, Graduate School of Biotechnology, 2Department of Oriental Medicinal Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea *These authors contributed equally to this work Abstract: Pharmacologically active stem of the oriental herbal adaptogen, Siberian ginseng, was employed for the ecofriendly synthesis of Siberian ginseng silver nanoparticles (Sg-AgNPs and Siberian ginseng gold nanoparticles (Sg-AuNPs. First, for metabolic characterization of the sample, liquid chromatography-tandem mass spectrometry analysis (indicated the presence of eleutherosides A and E, total phenol content, and total reducing sugar were analyzed. Second, the water extract of the sample mediated the biological synthesis of both Sg-AgNPs and Sg-AuNPs that were crystalline face-centered cubical structures with a Z-average hydrodynamic diameter of 126 and 189 nm, respectively. Moreover, Fourier transform infrared analysis indicated that proteins and aromatic hydrocarbons play a key role in the formation and stabilization of Sg-AgNPs, whereas phenolic compounds accounted for the synthesis and stability of Sg-AuNPs. 3-(4,5-Dimethyl-2-thiazolyl-2,5-diphenyl-2H tetrazolium bromide (MTT assay determined that Sg-AgNPs conferred strong cytotoxicity against MCF7 (human breast cancer cell line and was only slightly toxic to HaCaT (human keratinocyte cell line at 10 µg·mL-1. However, Sg-AuNPs did not display cytotoxic effects against both of the cell lines. The disc diffusion assay indicated a dose-dependent increase in the zone of inhibition of Staphylococcus aureus (ATCC 6538, Bacillus anthracis (NCTC 10340, Vibrio parahaemolyticus (ATCC 33844, and Escherichia coli (BL21 treated with Sg-AgNPs, whereas Sg-AuNPs did not show inhibitory activity. In addition, the 2,2-diphenyl-1

The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression

Directory of Open Access Journals (Sweden)

Dannehl K

2014-06-01

Full Text Available Katharina Dannehl,1 Winfried Rief,1 Markus J Schwarz,2 Annika Hennings,1 Sabine Riemer,1 Verena Selberdinger,3 Theresa Stapf,3 Frank Euteneuer11Division of Clinical Psychology and Psychotherapy, Philipps Universität Marburg, Marburg, Germany; 2Institute for Laboratory Medicine, Ludwig-Maximilian Universität, Munich, Germany; 3Department of Psychiatry, Ludwig-Maximilian Universität, Munich, GermanyContext: Elevated concentrations of proinflammatory cytokines have been hypothesized as an important factor in the pathophysiology of depression. Depression itself is considered to be a heterogeneous disorder. Current findings suggest that “cognitive” and “somatic” symptom dimensions are related to immune function in different ways. So far, little research has been done on the longitudinal aspects of inflammation in patients with major depression, especially with respect to different symptom dimensions of depression. Therefore, we investigated which aspects of depression may predict changes in tumor necrosis factor-alpha (TNF-alpha and interleukin (IL-6 over 4 weeks. Methods: Forty-one patients with major depression diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV, and 45 healthy controls were enrolled. Serum measurements of TNF-alpha and IL-6 were conducted at baseline and 4 weeks later. Psychometric measures included the assessment of cognitive-affective depressive symptoms and somatic symptoms during the last 7 days as well as somatic symptoms during the last 2 years. Results: Patients with depression showed increased levels of TNF-alpha (P<0.05 compared to healthy controls. Hierarchical regression analyses indicated that neither depressive nor somatic symptoms predict changes in proinflammatory cytokines in the whole sample of depressed patients. Moderation analyses and subsequent sex-stratified regression analyses indicated that higher somatoform symptoms during the last 2 years

Implementação do protocolo TRS-398 para feixes de elétrons no Hospital Israelita Albert Einstein

Directory of Open Access Journals (Sweden)

Rodrigues Laura Natal

2006-01-01

Full Text Available OBJETIVO: A fim de simplificar a utilização das tabelas correspondentes aos fatores de qualidade no TRS-398 da International Atomic Energy Agency na calibração cruzada da câmara de placas paralelas por comparação com uma câmara cilíndrica calibrada em um feixe de elétrons de qualidade Qcross, é introduzida uma energia intermediária e arbitrária Qint na qual a câmara de placas paralelas deverá ser calibrada. O objetivo deste trabalho consiste em avaliar a escolha desta energia intermediária. MATERIAIS E MÉTODOS: Uma câmara de placas paralelas da Scanditronix, modelo NACP-02, e uma câmara PTW Markus foram calibradas em dois aceleradores lineares da Varian, Clinac 2100C e Clinac 23EX, nas energias de 16 e 20 MeV, respectivamente. Como câmara de referência foi utilizada uma câmara da Nuclear Enterprises, modelo 2571, previamente calibrada em termos de Dw no Instituto de Pesquisas Energéticas e Nucleares, para um feixe de 60Co. RESULTADOS: Os fatores de calibração N D,w assim obtidos apresentam uma variação de 0,07%, o que pode ser considerado desprezível. Os valores de dose absorvida na água determinados no Clinac 2100C para uma Qint de 16 MeV apresentam uma variação de 0,04% para a menor energia (4 MeV e de 2,6% para a maior energia (16 MeV, em relação ao protocolo TRS-381. Já para uma Qint de 20 MeV, as variações observadas são de 1,3% e 3,5%. Por outro lado, as doses determinadas no Clinac 23EX para as Qint de 16 MeV e de 20 MeV são de 1,9% e 2,0% e de 2,8% e 3,0%, respectivamente. CONCLUSÃO: A escolha de Qint não é tão crítica assim, principalmente quando não de dispõem de feixes de elétrons que tenham na prática um valor de R50 exatamente igual a 7,5 g.cm-2.

Molecular composition of rainwater and aerosol during rain events in León, Spain, using high resolution mass spectrometry.

Science.gov (United States)

Fee, Anna

2017-04-01

Anna Fee (1), Markus Kalberer (1), Roberto Fraile (2), Amaya Castro (2), Ana. I. Calvo (2), Carlos Blanco-Alegre (2), Fernanda Oduber (2) and Mário Cerqueira (3). 1 Department of Chemistry, University of Cambridge, UK. 2 Department of Applied Chemistry and Physics, IMARENAB, University of León, Spain. 3 Department of Environmental Planning, University of Aveiro, Portugal. A wide range of atmospheric compounds which are present in rainwater are often also present in aerosol. They can be taken up during cloud droplet formation (in-cloud scavenging) or washed out during precipitation (below-cloud scavenging). Such compounds including aromatic hydrocarbons and organic nitrogen containing compounds are hazardous to health. In this study, the organic chemical composition of rainwater and aerosol from rain events in León, Spain, is being analysed using high resolution mass spectrometry. Collected rainwater along with high volume and low volume filters from rain events which occurred during spring, summer and winter of 2016 have been selected for analysis. Rainwater samples were prepared using Polymeric Reversed Phase Solid Phase Extraction (SPE) and filters have been extracted in water with and without SPE. Three different SPE polymer based sorbents were tested; one for extracting neutral compounds and two which are more suitable for extracting organic compounds containing sulphate and other polar functional groups. The sorbent for extracting neutral compounds was found to yield a higher number of compounds from the sample extraction than the other two varieties. Kendrick masses, Van Krevelen plots and carbon oxidation states have been investigated to identify compounds and patterns. Preliminary results show a predominance in peaks with O/C ratios between 0.2 and 0.7 and H/C ratios between 1 and 2 in both rain and aerosol samples which indicates substituted aromatic compounds. Cellulose material and fatty acids may also be present. The rain samples also have a

Barrier protective use of skin care to prevent chemotherapy-induced cutaneous symptoms and to maintain quality of life in patients with breast cancer

Directory of Open Access Journals (Sweden)

Wohlrab J

2014-08-01

Full Text Available Johannes Wohlrab,1 Nikola Bangemann,2 Anke Kleine-Tebbe,3 Marc Thill,4,5 Sherko Kümmel,6 Eva-Maria Grischke,7 Rainer Richter,8 Sophie Seite,9 Diana Lüftner10 1Martin Luther University Halle-Wittenberg, Department of Dermatology and Venereology, Halle (Saale, 2Interdisciplinary Breast Centre, University Hospital Charité Berlin, Campus Benjamin Franklin, Berlin, Germany, 3Breast Centre DRK Hospital, Berlin, 4Breast Centre University of Lübeck, Department of Gynaecology and Obstetrics, Lübeck, 5Department of Gynaecology and Obstetrics, Agaplesion Markus Hospital, Frankfurt am Main, 6Breast Centre and Clinic of Senology, Hospital Essen-Mitte, Essen, 7Breast Centre University of Tübingen, Department of Gynaecology, Tübingen, 8L'Oréal, Deutschland GmbH, Düsseldorf, 9La Roche-Posay, Dermatological Laboratories, Asnières, France; 10University Hospital Charité Berlin, Campus Benjamin Franklin, Department of Hematology, Oncology and Tumour Immunology, Berlin, Germany Purpose: Chemotherapy with anthracyclines, taxanes, or alkylating agents often causes cutaneous side effects. Nonspecific inhibition of the proliferative activity of keratinocytes has antidifferentiation effects that lead to defects in the barrier function and, thus, to dry, itchy, and irritable skin. These cutaneous symptoms reduce the quality of life of the patients considerably. Conditioning with topical application of niacinamide uses the cytoprotective and barrier stabilizing effect of vitamin B3. Patients and methods: A multicenter randomized crossover study investigated the influence of the test preparation on the quality of life compared to standard care for 73 patients with breast cancer undergoing adjuvant or neoadjuvant cytostatic therapy. Primary target parameter was the Dermatology Life Quality Index with its respective subscales after 6 weeks of a twice-daily application of the respective preparations. Additionally, specific symptoms such as pruritus, dryness, and

A Remote Collaborative Care Program for Patients with Depression Living in Rural Areas: Open-Label Trial.

Science.gov (United States)

Rojas, Graciela; Guajardo, Viviana; Martínez, Pablo; Castro, Ariel; Fritsch, Rosemarie; Moessner, Markus; Bauer, Stephanie

2018-04-30

of depressive patients. Future cost-effectiveness studies are needed. Clinicaltrials.gov NCT02200367; https://clinicaltrials.gov/ct2/show/NCT02200367 (Archived by WebCite at http://www.webcitation.org/6xtZ7OijZ). ©Graciela Rojas, Viviana Guajardo, Pablo Martínez, Ariel Castro, Rosemarie Fritsch, Markus Moessner, Stephanie Bauer. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 30.04.2018.

The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility

Directory of Open Access Journals (Sweden)

Frank KJ

2012-11-01

Full Text Available Kerstin J Frank,1,3 Ulrich Westedt,2 Karin M Rosenblatt,2 Peter Hölig,2 Jörg Rosenberg,2 Markus Mägerlein,2 Gert Fricker,3 Martin Brandl11Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark; 2Abbott GmbH and Co. KG, Ludwigshafen, Germany; 3Department of Pharmaceutical Technology, University of Heidelberg, Heidelberg, GermanyAbstract: Amorphous solid dispersions (ASDs are a promising formulation approach for poorly soluble active pharmaceutical ingredients (APIs, because they ideally enhance both dissolution rate and solubility. However, the mechanism behind this is not understood in detail. In the present study, we investigated the supramolecular and the nano/microparticulate structures that emerge spontaneously upon dispersion of an ASD in aqueous medium and elucidated their influence on solubility. The ASD, prepared by hot melt extrusion, contained the poorly soluble ABT-102 (solubility in buffer, 0.05 µg/mL, a hydrophilic polymer, and three surfactants. The apparent solubility of ABT-102 from the ASD-formulation was enhanced up to 200 times in comparison to crystalline ABT-102. At the same time, the molecular solubility, as assessed by inverse equilibrium dialysis, was enhanced two times. Asymmetrical flow field-flow fractionation in combination with a multiangle light-scattering detector, an ultraviolet detector, and a refractometer enabled us to separate and identify the various supramolecular assemblies that were present in the aqueous dispersions of the API-free ASD (placebo and of binary/ternary blends of the ingredients. Thus, the supramolecular assemblies with a molar mass between 20,000 and 90,000 could be assigned to the polyvinylpyrrolidone/vinyl acetate 64, while two other kinds of assemblies were assigned to different surfactant assemblies (micelles. The amount of ABT-102 remaining associated with each of the assemblies upon fractionation was quantified offline with high

Young Stars in Old Galaxies - a Cosmic Hide and Seek Game

Science.gov (United States)

2002-05-01

combination of the Hubble and the VLT with the latest space- and ground-based astronomical technology to break this new ground", says group leader Markus Kissler-Patig from the European Southern Observatory Headquarters in Garching (Germany). "Once we had found those young clusters, we then went on to observe them spectroscopically with another of the world's giant telescopes, the 10-m Keck on Hawaii - and this fully confirmed our results." A new important clue to the evolution of the Universe This is a surprising discovery since the stars in giant elliptical galaxies were until now believed to have formed exclusively early on in the history of the Universe. However, it is now clear that some of the old galaxies may have been hiding their true nature and have indeed experienced much more recent periods of major star formation. This is priceless new information for the current attempts to understand the early history of galaxies and the general theory of star formation in the Universe. More information The information presented in this Press Release is based on a research article that has been accepted for publication in the European journal "Astronomy & Astrophysics" ("Extragalactic Globular Clusters in the Near-Infrared: II. The Globular Cluster Systems of NGC 3115 and NGC 4365" by Thomas H. Puzia, Stephen E. Zepf, Markus Kissler-Patig, Michael Hilker, Dante Minniti and Paul Goudfrooij; astro-ph/0206147 ). Notes [1]: This press release is issued in coordination between ESA and ESO. The Hubble Space Telescope is an international cooperation between ESA and NASA. The team is presenting these results at the New Horizons in Globular Cluster Astronomy conference in Padova, Italy 24-28 June, 2002. [2]: The team consists of Thomas H. Puzia (Sternwarte Müenchen, Germany), Stephen E. Zepf (Yale University and Michigan State University, USA), Markus Kissler-Patig and Maren Hempel (ESO, Garching, Germany), Michael Hilker (Sternwarte Bonn, Germany), Dante Minniti (Universidad Catolica

Ginseng-berry-mediated gold and silver nanoparticle synthesis and evaluation of their in vitro antioxidant, antimicrobial, and cytotoxicity effects on human dermal fibroblast and murine melanoma skin cell lines

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Jiménez Pérez ZE

2017-02-01

Full Text Available Zuly Elizabeth Jiménez Pérez,1 Ramya Mathiyalagan,1 Josua Markus,1 Yeon-Ju Kim,2 Hyun Mi Kang,3 Ragavendran Abbai,1 Kwang Hoon Seo,2 Dandan Wang,2 Veronika Soshnikova,2 Deok Chun Yang1,21Department of Biotechnology and Ginseng Bank, 2Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea; 3Advanced Cosmeceutical Technology R&D Center, Suwon, Republic of KoreaAbstract: There has been a growing interest in the design of environmentally affable and biocompatible nanoparticles among scientists to find novel and safe biomaterials. Panax ginseng Meyer berries have unique phytochemical profile and exhibit beneficial pharmacological activities such as antihyperglycemic, antiobesity, antiaging, and antioxidant properties. A comprehensive study of the biologically active compounds in ginseng berry extract (GBE and the ability of ginseng berry (GB as novel material for the biosynthesis of gold nanoparticles (GBAuNPs and silver nanoparticles (GBAgNPs was conducted. In addition, the effects of GBAuNPs and GBAgNPs on skin cell lines for further potential biological applications are highlighted. GBAuNPs and GBAgNPs were synthesized using aqueous GBE as a reducing and capping agent. The synthesized nanoparticles were characterized for their size, morphology, and crystallinity. The nanoparticles were evaluated for antioxidant, anti-tyrosinase, antibacterial, and cytotoxicity activities and for morphological changes in human dermal fibroblast and murine melanoma skin cell lines. The phytochemicals contained in GBE effectively reduced and capped gold and silver ions to form GBAuNPs and GBAgNPs. The optimal synthesis conditions (ie, temperature and v/v % of GBE and kinetics were investigated. Polysaccharides and phenolic compounds present in GBE were suggested to be responsible for stabilization and functionalization of nanoparticles. GBAuNPs and GBAgNPs showed increased scavenging activity

Validation and ease of use of a new pen device for self-administration of recombinant human growth hormone: results from a two-center usability study

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Rapaport R

2013-09-01

Full Text Available Robert Rapaport,1 Paul Saenger,2 Heinrich Schmidt,3 Yukihiro Hasegawa,4 Michel Colle,5 Sandro Loche,6 Sandra Marcantonio,7 Walter Bonfig,8 Markus Zabransky,9 Fima Lifshitz10 1Division of Pediatric Endocrinology and Diabetes, Mount Sinai School of Medicine, 2Winthrop University Hospital, Mineola, NY, USA; 3University Children's Hospital, Division of Endocrinology and Diabetology, Munich, Germany; 4Department of Endocrinology and Metabolism, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan; 525 rue Boudet, Bordeaux, France; 6Servizio di Endocrinologia Pediatrica, Ospedale Microcitemico ASL Cagliari, Cagliari, Italy; 7Clinica de Endocrinologia Pediátrica, Londrina, Brazil; 8Division of Pediatric Endocrinology, Technical University München, Munich, Germany; 9Sandoz International GmbH, Holzkirchen, Germany; 10Pediatric Sunshine Academics, Inc, Santa Barbara, CA, USA Abstract: Close adherence to the recommended treatment regimen is important for the success of recombinant human growth hormone therapy, although nonadherence can be common. Ease of use and safety during use/storage are among several important factors in the design of a growth hormone injection device intended for long-term use. This study was performed to validate the usability and assess the ease of use of a new pen device (SurePal™ that has been developed to support daily administration of the recombinant human growth hormone product, Omnitrope® (somatropin. The primary objectives of the study were to assess if study participants, representing intended users of the pen in clinical practice, were able to perform an injection procedure into an injection pad effectively and safely and disassemble the pen without receiving a needlestick injury. A total of 106 participants (61 adults and 45 children/adolescents were enrolled at two study centers (one in the US, one in Germany. Results for both primary usability tasks met the predefined acceptance criteria, with >85% of

Patient Transfers and Risk of Back Injury: Protocol for a Prospective Cohort Study With Technical Measurements of Exposure.

Science.gov (United States)

Vinstrup, Jonas; Madeleine, Pascal; Jakobsen, Markus Due; Jay, Kenneth; Andersen, Lars Louis

2017-11-08

order to identify risk factors for back injuries related to patient transfers and intensity of LBP. Data collection is scheduled to commence during the winter of 2017. The design of this study is novel in its combination of technical measurements applied on a prospective cohort, and the results will provide important information about which assistive devices are associated with intensity of LBP and risk of back injury related to patient transfers. Furthermore, this study will shed light on the dose-response relationship between intensity, duration, and frequency of patient transfers and the intensity of LPB in Danish nurses, and will thereby help to guide and improve electronic health practices among this population. ©Jonas Vinstrup, Pascal Madeleine, Markus Due Jakobsen, Kenneth Jay, Lars Louis Andersen. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 08.11.2017.

IncobotulinumtoxinA use in aesthetic indications in daily practice: a European multicenter, noninterventional, retrospective study

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Pavicic T

2015-03-01

Full Text Available Tatjana Pavicic,1 Welf Prager,2 Markus Klöppel,3 Simon Ravichandran,4 Olivier Galatoire5 1Private Practice, Munich, Germany; 2Dr. Prager & Partner, Derma-Hamburg, Hamburg, Germany; 3Private Practice Clinic of Esthetic Surgery, MediCenter Munich-Solln, Munich, Germany; 4Clinetix Rejuvenation, Glasgow, Scotland, UK; 5Department of Ophthalmology, Adolphe Rothschild Ophthalmological Foundation, Paris, France Purpose: To characterize utilization patterns and treatment satisfaction with incobotulinumtoxinA for aesthetic indications and assess adherence to the Summary of Product Characteristics. Patients and methods: Data were collected retrospectively from physicians in Germany, France, and the UK regarding patients (n=638 treated with incobotulinumtoxinA for aesthetic indications. Data on indication, treatment interval, dose injected, physician and patient satisfaction, and adverse drug reactions were recorded according to routine daily practice. Results: Most patients (76.0% received incobotulinumtoxinA for glabellar frown lines (GFL and were given doses of ≤20 U. The majority of treatment intervals were 5 months or longer. Overall, 64.1% of patients were treated for off-label indications, sometimes in combination with treatment for GFL. The most frequently treated off-label indications were horizontal forehead lines (38.6% and/or crow's feet (CF; 31.7%; for CF, >95% of injected doses were ≤24 U. In Germany, a smaller proportion of patients were given incobotulinumtoxinA treatment for CF (27.6%, compared with France (40.4% and the UK (33.2%, although country-specific differences were less prominent when treatment cycle data for CF were examined. Treatment satisfaction among physicians and patients (overall, and for GFL specifically was very high, with excellent tolerability and only one mild adverse drug reaction reported. Conclusion: In daily practice, incobotulinumtoxinA is mainly used for GFL; however, its use for CF and horizontal forehead

Characterization of a new transmission detector for patient individualized online plan verification and its influence on 6MV X-ray beam characteristics

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Thoelking, Johannes; Sekar, Yuvaraj; Fleckenstein, Jens; Lohr, Frank; Wenz, Frederik; Wertz, Hansjoerg [Heidelberg Univ., University Medical Center Mannheim (Germany). Dept. of Radiation Oncology

2016-11-01

Online verification and 3D dose reconstruction on daily patient anatomy have the potential to improve treatment delivery, accuracy and safety. One possible implementation is to recalculate dose based on online fluence measurements with a transmission detector (TD) attached to the linac. This study provides a detailed analysis of the influence of a new TD on treatment beam characteristics. The influence of the new TD on surface dose was evaluated by measurements with an Advanced Markus Chamber (Adv-MC) in the build-up region. Based on Monte Carlo simulations, correction factors were determined to scale down the over-response of the Adv-MC close to the surface. To analyze the effects beyond d{sub max} percentage depth dose (PDD), lateral profiles and transmission measurements were performed. All measurements were carried out for various field sizes and different SSDs. Additionally, 5 IMRT-plans (head and neck, prostate, thorax) and 2 manually created test cases (3 x 3 cm{sup 2} fields with different dose levels, sweeping gap) were measured to investigate the influence of the TD on clinical treatment plans. To investigate the performance of the TD, dose linearity as well as dose rate dependency measurements were performed. With the TD inside the beam an increase in surface dose was observed depending on SSD and field size (maximum of +11%, SSD = 80 cm, field size = 30 x 30 cm{sup 2}). Beyond d{sub max} the influence of the TD on PDDs was below 1%. The measurements showed that the transmission factor depends slightly on the field size (0.893-0.921 for 5 x 5 cm{sup 2} to 30 x 30 cm{sup 2}). However, the evaluation of clinical IMRT-plans measured with and without the TD showed good agreement after using a single transmission factor (γ{sub (2%/2mm)} > 97%, δ{sub ±3%} >95%). Furthermore, the response of TD was found to be linear and dose rate independent (maximum difference <0.5% compared to reference measurements). When placed in the path of the beam, the TD introduced

Properties of a new variable collimator at orthovoltage energies

International Nuclear Information System (INIS)

Lee, K.; Butson, M.; Metcalfe, P.; University of Wollongong, Wollongong, NSW

1996-01-01

Full text: Beam characteristics of a Therapax DXT 300 Orthovoltage Machine are investigated using fixed collimators or 'cones' and a variable collimator. Previously, fixed collimators have always been used throughout patient treatments. The variable collimator is an optional accessory to the DXT 300 machine and has just been implemented at our centre. The variable collimator mounts to the DXT 300 at the same position as the fixed collimators and produces rectangular field sizes up to 20 x 20 cmm at 50 cm FSD. Surface/near surface charge measurements were performed for the variable collimator and various configurations of cones for a 10 x 10 cm field at 250kVp and a FSD of 50cm in solid water using a Markus Type 329 parallel plate ionisation chamber connected via a shielded triaxial cable to a 2570/1 NE Farmer electrometer. Central axis percentage depth doses and beam profiles were measured using a Scanditronix RK ionisation chamber in a RFA300 water tank for both cones and the variable collimator. This data was then transferred to the Target Series 2 computer planning system for isodose display. Measurements were performed at 250 kVp. Beam profiles were scanned both perpendicular to and along the cathode-anode direction. A change in charge measured at the surface and to 1 mm depth for the variable collimator and the cones was observed. The normal cone and the variable collimator have surface charges of 100% and 98% respectively. Maximum surface charge occurred for the open-end 'lead' cone. A comparison was made between the central axis percentage depth dose produced by the cones and variable collimator for field sizes of 10 x 10cm and 20 x 20 cm. Maximum dose for the cones is deposited at the surface whereas for the variable collimator there is a slight build-up region before maximum dose is deposited at a depth of 1 mm. Upon comparing the beam profiles produced by the variable collimator and the cones, it was observed that the width of the penumbra differed by

Book Reviews

Directory of Open Access Journals (Sweden)

Tim Hoppen

1995-01-01

Hoppen, Gerard Termorshuizen, In de binnenland van Java; Vier negentiende-eeuwse reisverhalen. Leiden: KITLV Uitgeverij, 1993, 102 pp. - Niels Mulder, Monique Zaini-Lajoubert, L’image de la femme dans les littératures modernes indonésienne et malaise. Paris: Association Archipel, Cahier d’Archipel 24, 1994, ix + 221 pp. - A. Niehof, Rosalia Sciortino, CARE-takers of CURE; A study of health centre nurses in rural Central Java. Amsterdam: Jolly/Het Spinhuis Publishers, 1992, 318 pp. - A.J. Plaisier, B. Plaisier, Over bruggen en grenzen; De communicatie van het evangelie in het Torajagebied (1913-1942. Zoetermeer: Boekencentrum, 1993, xiv + 701 pp. - Anton Ploeg, Nonie Sharp, The Morning Star in Papua Barat, written in association with Markus Wonggor Kaisiëpo. North Carlton, Vic., Australia: Arena Publications, 1994, xx + 140 pp.

Mental toughness, sleep disturbances, and physical activity in patients with multiple sclerosis compared to healthy adolescents and young adults

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Sadeghi Bahmani D

2016-06-01

Full Text Available Dena Sadeghi Bahmani,1 Markus Gerber,2 Nadeem Kalak,1 Sakari Lemola,3 Peter J Clough,4 Pasquale Calabrese,5 Vahid Shaygannejad,6 Uwe Pühse,2 Edith Holsboer-Trachsler,1 Serge Brand1,2 1Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders, 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland; 3Department of Psychology, University of Warwick, Coventry, 4Department of Psychology, Manchester Metropolitan University, Manchester, UK; 5Division of Molecular and Cognitive Neuroscience, University of Basel, Basel, Switzerland; 6Department of Neurology and Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran Background: Multiple sclerosis (MS is the most common chronic autoimmune demyelinating and inflammatory disease of the central nervous system, afflicting both the body and mind. The risk of suffering from MS is 2.5–3.5 times greater in females than in males. While there is extant research on fatigue, depression, and cognitive impairment in patients with MS during its clinical course, there is a lack of research focusing on sleep, psychological functioning, and physical activity (PA at the point of disease onset. The aims of the present study were therefore, to assess the markers of mental toughness (MT as a dimension of psychological functioning, sleep disturbances (SD, and PA among patients at the moment of disease onset and to compare these with the corresponding values for healthy adolescents and young adults. Methods: A total of 23 patients with MS at disease onset (mean age =32.31 years; 91% females, 23 healthy adolescents (mean age =17.43 years; 82% females, and 25 healthy young adults (mean age =20.72 years; 80% females took part in the study. They completed questionnaires covering sociodemographic data, MT, SD, and PA. Results: Patients with MS had similar scores for MT traits as those in healthy

High dose-per-pulse electron beam dosimetry: Commissioning of the Oriatron eRT6 prototype linear accelerator for preclinical use.

Science.gov (United States)

Jaccard, Maud; Durán, Maria Teresa; Petersson, Kristoffer; Germond, Jean-François; Liger, Philippe; Vozenin, Marie-Catherine; Bourhis, Jean; Bochud, François; Bailat, Claude

2018-02-01

The Oriatron eRT6 is an experimental high dose-per-pulse linear accelerator (linac) which was designed to deliver an electron beam with variable dose-rates, ranging from a few Gy/min up to hundreds of Gy/s. It was built to study the radiobiological effects of high dose-per-pulse/dose-rate electron beam irradiation, in the context of preclinical and cognitive studies. In this work, we report on the commissioning and beam monitoring of the Oriatron eRT6 prototype linac. The beam was characterized in different steps. The output stability was studied by performing repeated measurements over a period of 20 months. The relative output variations caused by changing beam parameters, such as the temporal electron pulse width, the pulse repetition frequency and the pulse amplitude were also analyzed. Finally, depth dose curves and field sizes were measured for two different beam settings, resulting in one beam with a conventional radiotherapy dose-rate and one with a much higher dose-rate. Measurements were performed with Gafchromic EBT3 films and with a PTW Advanced Markus ionization chamber. In addition, we developed a beam current monitoring system based on the signals from an induction torus positioned at the beam exit of the waveguide and from a graphite beam collimator. The stability of the output over repeated measurements was found to be good, with a standard deviation smaller than 1%. However, non-negligible day-to-day variations of the beam output were observed. Those output variations showed different trends depending on the dose-rate. The analysis of the relative output variation as a function of various beam parameters showed that in a given configuration, the dose-rate could be reliably varied over three orders of magnitude. Interdependence effects on the output variation between the parameters were also observed. The beam energy and field size were found to be slightly dose-rate-dependent and suitable mainly for small animal irradiation. The beam monitoring

Chronicle of a Death Foretold

Science.gov (United States)

2007-05-01

Using ESO's VLTI on Cerro Paranal and the VLBA facility operated by NRAO, an international team of astronomers has made what is arguably the most detailed study of the environment of a pulsating red giant star. They performed, for the first time, a series of coordinated observations of three separate layers within the star's tenuous outer envelope: the molecular shell, the dust shell, and the maser shell, leading to significant progress in our understanding of the mechanism of how, before dying, evolved stars lose mass and return it to the interstellar medium. S Orionis (S Ori) belongs to the class of Mira-type variable stars. It is a solar-mass star that, as will be the fate of our Sun in 5 billion years, is nearing its gloomy end as a white dwarf. Mira stars are very large and lose huge amounts of matter. Every year, S Ori ejects as much as the equivalent of Earth's mass into the cosmos. ESO PR Photo 25a/07 ESO PR Photo 25a/07 Evolution of the Mira-type Star S Orionis "Because we are all stardust, studying the phases in the life of a star when processed matter is sent back to the interstellar medium to be used for the next generation of stars, planets... and humans, is very important," said Markus Wittkowski, lead author of the paper reporting the results. A star such as the Sun will lose between a third and half of its mass during the Mira phase. S Ori pulsates with a period of 420 days. In the course of its cycle, it changes its brightness by a factor of the order of 500, while its diameter varies by about 20%. Although such stars are enormous - they are typically larger than the current Sun by a factor of a few hundred, i.e. they encompass the orbit of the Earth around the Sun - they are also distant and to peer into their deep envelopes requires very high resolution. This can only be achieved with interferometric techniques. ESO PR Photo 25b/07 ESO PR Photo 25b/07 Structure of S Ori (Artist's Impression) "Astronomers are like medical doctors, who use various

Materiomics: biological protein materials, from nano to macro

Directory of Open Access Journals (Sweden)

Steven Cranford

2010-11-01

Full Text Available Steven Cranford, Markus J BuehlerCenter for Materials Science and Engineering, Laboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USAAbstract: Materiomics is an emerging field of science that provides a basis for multiscale material system characterization, inspired in part by natural, for example, protein-based materials. Here we outline the scope and explain the motivation of the field of materiomics, as well as demonstrate the benefits of a materiomic approach in the understanding of biological and natural materials as well as in the design of de novo materials. We discuss recent studies that exemplify the impact of materiomics – discovering Nature’s complexity through a materials science approach that merges concepts of material and structure throughout all scales and incorporates feedback loops that facilitate sensing and resulting structural changes at multiple scales. The development and application of materiomics is illustrated for the specific case of protein-based materials, which constitute the building blocks of a variety of biological systems such as tendon, bone, skin, spider silk, cells, and tissue, as well as natural composite material systems (a combination of protein-based and inorganic constituents such as nacre and mollusk shells, and other natural multiscale systems such as cellulose-based plant and wood materials. An important trait of these materials is that they display distinctive hierarchical structures across multiple scales, where molecular details are exhibited in macroscale mechanical responses. Protein materials are intriguing examples of materials that balance multiple tasks, representing some of the most sustainable material solutions that integrate structure and function despite severe limitations in the quality and quantity of material building blocks. However, up until now, our attempts to analyze and

Anterior cruciate ligament reconstruction using bone plug-free quadriceps tendon autograft: intermediate-term clinical outcome after 24–36 months

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Schulz AP

2013-11-01

Full Text Available Arndt P Schulz,1 Vivien Lange,2 Justus Gille,1 Christine Voigt,3 Susanne Fröhlich,4 Markus Stuhr,1 Christian Jürgens5 1Department of Orthopedics, Trauma, and Sports Medicine, University Hospital Lübeck, Lübeck, Germany; 2Department of Rehabilitation, Sana Regio Klinikum, Wedel, Germany; 3Department of Sports Medicine and Arthroscopy, Diakoniekrankenhaus Friederikenstift, Hannover, Germany; 4Department of Orthopedics, University of Rostock, Rostock, Germany; 5Department of Orthopedics, Trauma, and Sports Medicine, BG Trauma Hospital Hamburg, Hamburg, Germany Introduction: Although known as a possible graft option for decades, quadriceps tendon grafts have often been termed a second-line graft option. We report a consecutive case series using this method as the primary treatment line. The rationale for this study was to evaluate the midterm results of this method in a prospective and consecutive case series. The primary study question was to determine the clinical results 24–36 months after primary anterior cruciate ligament (ACL reconstruction using a bone plug-free quadriceps tendon autograft fixed with bioabsorbable cross-pins. Materials and methods: The study population included 55 patients, of whom 24 were female (43.6%. The mean age at the index procedure was 31.7 years (15–58 years. All patients received an ACL construction using a bone block-free quadriceps tendon graft fixed with resorbable cross-pins. The postoperative regimen included partial weight-bearing for 3 weeks and flexion limited to 90° for six weeks; an orthosis was not used. The mean follow-up duration was 29.5 months (24.3–38.5 months after the index procedure. The International Knee Documentation Committee (IKDC subjective score and examination form was assessed, as well as the Lysholm and Gillquist score and the Tegner activity index. The Rolimeter arthrometer was used to assess the anterior laxity of the knee. Results: Graft harvesting was possible in all cases

X-ray sterilization of insects and microorganisms for cultural heritage applications

Science.gov (United States)

Borgognoni, F.; Vadrucci, M.; Bazzano, G.; Ferrari, P.; Massa, S.; Moretti, R.; Calvitti, M.; Ronsivalle, C.; Moriani, A.; Picardi, L.

2017-09-01

The APAM (Development of Particle Accelerators and Medical Applications) Laboratory of the ENEA Frascati Research Center is engaged in the preservation of cultural heritage as part of the COBRA (Sviluppo e diffusione di metodi, tecnologie e strumenti avanzati per la COnservazione dei Beni culturali, basati sull'applicazione di Radiazioni e di tecnologie Abilitanti) project addressed to the transfer of innovative technologies and methodologies from research to small and medium enterprises involved in the restorative measures. This work aims to demonstrate the effectiveness of ionizing radiation on the disinfection of biodegraded art objects. The conventional methods for the disinfestation of works of art, using chemicals toxic to humans and environment, might cause some damage to the treated material even on micrometric scale (i. e. either cellulose degradation). Ionizing radiations interact with the infesting biological material causing an irreversible DNA degradation. For this reason, they are certainly suitable for removal treatments of both macro organisms and bacterial colonies. A 4.8 MeV electron linear accelerator, normally dedicated to the characterization of dose detectors and radiographies, has been employed to produce Bremsstrahlung X-rays through a lead converter. The spectral fluence of the radiation source has been calculated using the Monte Carlo MCNPX code. The dosimetric characterization of the radiation field has been made using radiochromic films sensitive in the dose range of our interest (from 50 to 500 Gy) calibrated with a Markus ionization chamber. The irradiation of the artifact prototypes are made within a lead shielded room at a variable distance from the X-rays source. Samples subjected to irradiation consist of a soil bacterium, Agrobacterium rhizogenes, and an insect, Stegobium paniceum, that are found as wall paintings invasive coloniser and as a pest of books, wood works and paintings, respectively. Tests of irradiation have been

Rebound macular edema following oral acetazolamide therapy for juvenile X-linked retinoschisis in an Italian family

Directory of Open Access Journals (Sweden)

Galantuomo MS

2016-11-01

Full Text Available Maria Silvana Galantuomo,1,* Maurizio Fossarello,1 Alberto Cuccu,1 Roberta Farci,1 Markus N Preising,2 Birgit Lorenz,2 Pietro Emanuele Napoli1,* 1Department of Surgical Sciences, Eye Clinic, University of Cagliari, Cagliari, Italy; 2Department of Ophthalmology, Faculty of Medicine, Justus-Liebig-University, Giessen, Germany *These authors contributed equally to this work Background: Juvenile X-linked retinoschisis (RS1, OMIM: 312700 is a hereditary vitreoretinal dystrophy characterized by bilateral foveal schisis and, in half of the patients, splitting through the nerve fiber layer in the peripheral retina. In the first decade of life, patients usually develop a decrease in visual acuity. Long-term visual outcomes can be poor due to the limited number of known successful treatments. Purpose: The purposes of this study were to present, for the first time, a p.Arg197Cys missense mutation in the RS1 gene (OMIM: 300839 in a four-generation Italian family with RS1 and to examine the clinical response to the treatment with acetazolamide tablets alone or in combination with dorzolamide eye drops as assessed by spectral-domain optical coherence tomography (SD-OCT. Methods: Eleven individuals, including two brothers with RS1 (patients 1 and 2, underwent a full medical history examination and a comprehensive ocular assessment that involved SD-OCT, fluorescein angiography, electroretinography and DNA analysis. Each RS1 patient received oral acetazolamide (375 mg daily during the first three months. Thereafter, patient 1 continued only with dorzolamide eyedrops three times a day for a period of three months, while patient 2 spontaneously stopped both medications. Results: Sequence analysis of the RS1 gene identified a hemizygous c.589C>T (p.Arg197Cys missense mutation in exon 6, which has not been previously reported in an Italian family. A different response to the medical therapy was observed in the four eyes of the two affected brothers hemizygous for

Contribution to the planning and dosimetry of photon beams applied to radiosurgery and stereotactic radiotherapy; Contribuicao ao planejamento e a dosimetria de feixes de fotons aplicados a radiocirurgia e a radioterapia estereotaxica

Energy Technology Data Exchange (ETDEWEB)

Santos, Walter Menezes

2003-08-15

Radiosurgery and stereotactic radiotherapy are irradiation techniques that use small diameter photon beams for treating intracranial lesions such as pituitary adenomas, acoustic tumors and arterio-venous malformations which are inaccessible for surgery. These treatment techniques are characterized by the use of very small radiation beams which deliver a precisely measured dose to the target volume, while sparing the surrounding healthy tissue. Treatment can be performed by using multiple {sup 60}Co gamma-ray sources (in the so-called 'Gamma Knife'), charged particles or X-ray beams produced by linear accelerators. The prescribed dose can be given in a single session or in multiple fractions, as in conventional radiotherapy. The success of the treatment depends, among other factors, of the accurate determination of the parameters that characterize the radiation beam produced by the equipment, as well as, of a well designed quality assurance program. In this study, the dosimetric parameters of a set of collimating cones of a Radionics{sup TM} treatment system applied to two 6 MV- photon beams (Clinac 600C - Varian{sup TM}, and Mevatron MD2 - Siemens{sup TM}) were evaluated by using a water filled PMMA simulator. Measurements were carried out for photon beam diameters ranging from 12.5 to 40.0 mm for the Clinac-600C and from 5.0 to 50.0 mm for the Mevatron MD2. The parameters were evaluated by using a parallel plate ionization chamber (Markus), Kodak X-Omat V dosimetric films, thermoluminescent dosemeters (Harschaw, TLD-100) and photodiodes. The maximum tissue-ratio, the off-axis profile and the output factors were determined and the results were compared to those reported elsewhere. A study of the dosimetric characteristics of some commercially available phototransistors was also carried out. The results showed that these electronic components can be successfully used for measuring the dosimetric parameters of small diameter photon beans used in

Contribution to the planning and dosimetry of photon beams applied to radiosurgery and stereotactic radiotherapy; Contribuicao ao planejamento e a dosimetria de feixes de fotons aplicados a radiocirurgia e a radioterapia estereotaxica

Energy Technology Data Exchange (ETDEWEB)

Santos, Walter Menezes

2003-08-15

Radiosurgery and stereotactic radiotherapy are irradiation techniques that use small diameter photon beams for treating intracranial lesions such as pituitary adenomas, acoustic tumors and arterio-venous malformations which are inaccessible for surgery. These treatment techniques are characterized by the use of very small radiation beams which deliver a precisely measured dose to the target volume, while sparing the surrounding healthy tissue. Treatment can be performed by using multiple {sup 60}Co gamma-ray sources (in the so-called 'Gamma Knife'), charged particles or X-ray beams produced by linear accelerators. The prescribed dose can be given in a single session or in multiple fractions, as in conventional radiotherapy. The success of the treatment depends, among other factors, of the accurate determination of the parameters that characterize the radiation beam produced by the equipment, as well as, of a well designed quality assurance program. In this study, the dosimetric parameters of a set of collimating cones of a Radionics{sup TM} treatment system applied to two 6 MV- photon beams (Clinac 600C - Varian{sup TM}, and Mevatron MD2 - Siemens{sup TM}) were evaluated by using a water filled PMMA simulator. Measurements were carried out for photon beam diameters ranging from 12.5 to 40.0 mm for the Clinac-600C and from 5.0 to 50.0 mm for the Mevatron MD2. The parameters were evaluated by using a parallel plate ionization chamber (Markus), Kodak X-Omat V dosimetric films, thermoluminescent dosemeters (Harschaw, TLD-100) and photodiodes. The maximum tissue-ratio, the off-axis profile and the output factors were determined and the results were compared to those reported elsewhere. A study of the dosimetric characteristics of some commercially available phototransistors was also carried out. The results showed that these electronic components can be successfully used for measuring the dosimetric parameters of small diameter photon beans used in radiosurgery

Acceptance of a reusable self-injection device for recombinant human growth hormone: final data from a questionnaire-based, cross-sectional, international, multicenter, observational study in pediatric patients

Directory of Open Access Journals (Sweden)

Schnabel D

2016-09-01

Full Text Available Dirk Schnabel,1 Carl-Joachim Partsch,2 Muriel Houang,3 Sarah Ehtisham,4 Helen Johnstone,5 Markus Zabransky,6 Wieland Kiess7 1Pediatric Endocrinology, Center for Chronic Sick Children, Otto-Heubner-Centrum für Kinder- und Jugendmedizin, Charite, University Medicine, Berlin, Germany; 2Endokrinologikum Hamburg, Hamburg, Germany; 3Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, Paris, France; 4Mediclinic City Hospital, Dubai Healthcare City, Dubai, United Arab Emirates; 5The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK; 6Sandoz International GmbH, Holzkirchen, 7Department of Women and Child Health, Hospital for Children and Adolescents, University Hospitals, University of Leipzig, Leipzig, Germany Background: A questionnaire-based survey was conducted to assess attitudes toward a reusable self-injection system (SurePal™ among pediatric patients with growth disturbances who were prescribed treatment with Omnitrope® within routine clinical practice.Methods: This was a multicenter, observational study, incorporated into the noninterventional PAtients TReated with Omnitrope® (PATRO Children study. Included subjects, or their caregivers, completed a questionnaire on the following five main areas: attractiveness of SurePal™, training received, using the device, the low drug wastage system, and experience versus other devices used previously (pretreated patients. Responses were based on a 5-point scale, with 2 being the best possible outcome and −2 the worst possible outcome.Results: In total, 550 patients were included in this study (338 from France, 169 from Germany, and 43 from the UK. The mean age ± standard deviation of participants was 10.8±3.5 years; the majority (57% were male and growth hormone treatment naïve (88%. Almost half (49.8% of children prepared their SurePal™ for injection themselves and 45.5% performed injections themselves. As patients progressed into their teens, the majority

Contribution to the planning and dosimetry of photon beams applied to radiosurgery and stereotactic radiotherapy

International Nuclear Information System (INIS)

Santos, Walter Menezes

2003-08-01

Radiosurgery and stereotactic radiotherapy are irradiation techniques that use small diameter photon beams for treating intracranial lesions such as pituitary adenomas, acoustic tumors and arterio-venous malformations which are inaccessible for surgery. These treatment techniques are characterized by the use of very small radiation beams which deliver a precisely measured dose to the target volume, while sparing the surrounding healthy tissue. Treatment can be performed by using multiple 60 Co gamma-ray sources (in the so-called 'Gamma Knife'), charged particles or X-ray beams produced by linear accelerators. The prescribed dose can be given in a single session or in multiple fractions, as in conventional radiotherapy. The success of the treatment depends, among other factors, of the accurate determination of the parameters that characterize the radiation beam produced by the equipment, as well as, of a well designed quality assurance program. In this study, the dosimetric parameters of a set of collimating cones of a Radionics TM treatment system applied to two 6 MV- photon beams (Clinac 600C - Varian TM , and Mevatron MD2 - Siemens TM ) were evaluated by using a water filled PMMA simulator. Measurements were carried out for photon beam diameters ranging from 12.5 to 40.0 mm for the Clinac-600C and from 5.0 to 50.0 mm for the Mevatron MD2. The parameters were evaluated by using a parallel plate ionization chamber (Markus), Kodak X-Omat V dosimetric films, thermoluminescent dosemeters (Harschaw, TLD-100) and photodiodes. The maximum tissue-ratio, the off-axis profile and the output factors were determined and the results were compared to those reported elsewhere. A study of the dosimetric characteristics of some commercially available phototransistors was also carried out. The results showed that these electronic components can be successfully used for measuring the dosimetric parameters of small diameter photon beans used in radiosurgery. Measurements were also

Photovoltaic solar energy. Proceedings; Photovoltaische Solarenergie. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

and limits (Mike Meinhardt); (17) Washing with the sun - Direct consumption of locally generated PV current by means of directed load shift in private households (Georg Bopp); (18) Efficiency by synergy. Export initiative renewable energies (Berthold Breid); (19) Modular PV power supply in the Empire of the Midth (Michael Wollny); (20) Breakthrough to a new era of PV hybrid systems with the help of standardised components communication? (Michael Mueller); (21) New PV stand-alone supply for frequency variable loads (Wolfgang Hernschier); (22) Characterization of solar batteries in long-term investigations according IEC 61427 (Wolfgang Wiesner); (23) Professional PV plant configuration - the status quo of the PV prpgrams (Mike Zehner); (24) Simulating renewable power projects with greenius{sup Free} (Volker Quaschning); (25) Analysis of the effect of shade and equivalent circuit of PV modules with the simulation software ''Solar Pro'' (Yusuke Mataki); (26) From data sheet values to the system gain - on realistic modelling of small PV generators (Hans Georg Beyer); (27) Form follows function - follows form function? - Ineractions between building functions and photovoltaic (Wolfgang Willkomm); (28) Market chances and technology perspectives for the Swiss facade construction by means of building integrated PV systems (Reto Miloni); (29) Passiv solar office building BIOHAUS Paderborn - architectonic overview and a first energy balance (Willi Ernst, Ralf Zirkler); (30) Building integration and education in Austria (Gernot Becker); (31) Photovoltaic and light (Thomas Herzog); (32) 10 years of test experience with the certification of design of photovoltaic modules (Andreas Cox); (32) Large size solar cells and the IEC 61215 - New challenges for the module junction (Eckehard Hofmueller); (33) Limits of power output optimisation of PV arrays by pre-sorting of PV modules (Werner Herrmann); (34) Coloured and patterned CIS modules (Dieter Geyer); (35) Energy

Skin dose estimation for various beam modifiers and source-to-surface distances for 6MV photons

Directory of Open Access Journals (Sweden)

Yadav Girigesh

2009-01-01

Full Text Available The purpose of this study was to learn the skin dose estimation for various beam modifiers at various source-to-surface distances (SSDs for a 6 MV photon. Surface and buildup region doses were measured with an acrylic slab phantom and Markus 0.055 cc parallel plate (PP ionization chamber. Measurements were carried out for open fields, motorized wedge fields, acrylic block tray fields ranging from 3 x 3 cm 2 to 30 x 30 cm 2 . Twenty-five percent of the field was blocked with a cerrobend block and a Multileaf collimator (MLC. The effect of the blocks on the skin dose was measured for a 20 x 20 cm 2 field size, at 80 cm, 100 cm and 120 cm SSD. During the use of isocentric treatments, whereby the tumor is positioned at 100 cm from the source, depending on the depth of the tumor and size of the patient, the SSD can vary from 80 cm to 100 cm. To achieve a larger field size, the SSD can also be extended up to 120 cm at times. The skin dose increased as field size increased. The skin dose for the open 10 x10 cm 2 field was 15.5%, 14.8% and 15.5% at 80 cm, 100 cm and 120 cm SSDs, respectively. The skin dose due to a motorized 60 0 wedge for the 10 x 10 cm 2 field was 9.9%, 9.5%, and 9.5% at 80 cm, 100 cm and 120 cm SSDs. The skin dose due to acrylic block tray, of thickness 1.0 cm for a 10 x 10 cm 2 field was 27.0%, 17.2% and 16.1% at 80, 100 and 120 cm SSD respectively. Due to the use of an acrylic block tray, the surface dose was increased for all field sizes at the above three SSDs and the percentage skin dose was more dominant at the lower SSD and larger field size. The skin dose for a 30 x 30 cm 2 field size at 80 cm SSD was 38.3% and it was 70.4% for the open and acrylic block tray fields, respectively. The skin doses for motorized wedge fields were lower than for open fields. The effect of SSDs on the surface dose for motorized 60° wedge fields was not significant for a small field size (difference was less than 1% up to a 15 x 15 cm 2 field size

Reliability of an e-PRO Tool of EORTC QLQ-C30 for Measurement of Health-Related Quality of Life in Patients With Breast Cancer: Prospective Randomized Trial.

Science.gov (United States)

Wallwiener, Markus; Matthies, Lina; Simoes, Elisabeth; Keilmann, Lucia; Hartkopf, Andreas D; Sokolov, Alexander N; Walter, Christina B; Sickenberger, Nina; Wallwiener, Stephanie; Feisst, Manuel; Gass, Paul; Fasching, Peter A; Lux, Michael P; Wallwiener, Diethelm; Taran, Florin-Andrei; Rom, Joachim; Schneeweiss, Andreas; Graf, Joachim; Brucker, Sara Y

2017-09-14

differences were found in 27 of 30 single items and in 14 of 15 scales, whereas a statistically significant correlation in the test of consistency was found in all 30 single items and all 15 scales. The evaluated e-PRO version of the EORTC QLQ-C30 is reliable for patients with both adjuvant and metastatic breast cancer, showing a high correlation in almost all questions (and in many scales). Thus, we conclude that the validated paper-based PRO assessment and the e-PRO tool are equally valid. However, the reliability should also be analyzed in other prospective trials to ensure that usability is reliable in all patient groups. ClinicalTrials.gov NCT03132506; https://clinicaltrials.gov/ct2/show/NCT03132506 (Archived by WebCite at http://www.webcitation.org/6tRcgQuou). ©Markus Wallwiener, Lina Matthies, Elisabeth Simoes, Lucia Keilmann, Andreas D Hartkopf, Alexander N Sokolov, Christina B Walter, Nina Sickenberger, Stephanie Wallwiener, Manuel Feisst, Paul Gass, Peter A Fasching, Michael P Lux, Diethelm Wallwiener, Florin-Andrei Taran, Joachim Rom, Andreas Schneeweiss, Joachim Graf, Sara Y Brucker. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.09.2017.

Using the framework of corporate culture in “mergers” to support the development of a cultural basis for integrative medicine – guidance for building an integrative medicine department or service

Directory of Open Access Journals (Sweden)

Witt CM

2015-01-01

Full Text Available Claudia M Witt,1–3 Marion Pérard,2 Brian Berman,3,4 Susan Berman,4 Timothy C Birdsall,5 Horst Defren,6 Sherko Kümmel,7 Gary Deng,8 Gustav Dobos,9 Atje Drexler,10 Christine Holmberg,2 Markus Horneber,11 Robert Jütte,9 Lori Knutson,12 Christopher Kummer,13 Susanne Volpers,14 David Schweiger15 1University Hospital Zurich, Institute for Complementary and Integrative Medicine, Zurich, Switzerland; 2Institute for Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin, Berlin, Germany; 3University of Maryland School of Medicine, Center for Integrative Medicine, Baltimore, Maryland, USA; 4The Institute for Integrative Health, Baltimore, USA; 5Cancer Treatment Centers of America, Goodyear, Arizona, USA, 6Kliniken Essen Mitte, Evang, Huyssen-Stiftung/Knappschaft GmbH Patientenmanagement, Essen, Germany; 7Department of Senology, Breast Center, Kliniken Essen-Mitte, Evang. Huyssens Stiftung, Knappschaft GmbH, Essen, Germany; 8Memorial Sloan-Kettering Cancer Center, New York, USA; 9Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Academic Teaching Hospital of the University of Duisburg-Essen, Germany; 10Robert Bosch Foundation GmbH, Stuttgart, Germany; 11Department of Internal Medicine, Division of Oncology and Hematology, Paracelsus Medical University, Klinikum Nürnberg, Germany; 12Integrative Healthcare Solutions, Minneapolis, Minnesota, USA; 13Institute of Mergers, Acquisitions and Alliances (IMAA, Zurich, Switzerland; 14Frauenselbsthilfe nach Krebs, Bonn, Germany; 15Schweiger, Schweiger & Associates, Hilton Head Island, South Carolina, USA Background: An increasing number of clinics offer complementary or integrative medicine services; however, clear guidance about how complementary medicine could be successfully and efficiently integrated into conventional health care settings is still lacking. Combining conventional and complementary medicine into integrative medicine can be regarded as a kind of

EDITORIAL: From reciprocal space to real space in surface science From reciprocal space to real space in surface science

Science.gov (United States)

Bartels, Ludwig; Ernst, Karl-Heinz

2012-09-01

Triest.let's finish—aus basta Some move atoms around to hear how they sound.Karl-Heinz Rieder, Erice, 6 April 1998 From reciprocal space to real space in surface science contents From reciprocal space to real space in surface scienceLudwig Bartels and Karl-Heinz Ernst Karl-Heinz Reider: the quiet pioneerGiorgio Benedek Scattering of CO and N2 molecules by a graphite surfaceJunepyo Oh, Takahiro Kondo, Keitaro Arakawa, Yoshihiko Saito, Junji Nakamura, W W Hayes and J R Manson Helium, neon and argon diffraction from Ru(0001)M Minniti, C Díaz, J L Fernández Cuñado, A Politano, D Maccariello, F Martín, D Farías and R Miranda Enhanced charge transfer in a monolayer of the organic charge transfer complex TTF-TNAP on Au(111)T R Umbach, I Fernandez-Torrente, J N Ladenthin, J I Pascual and K J Franke Extended pattern recognition scheme for self-learning kinetic Monte Carlo simulationsSyed Islamuddin Shah, Giridhar Nandipati, Abdelkader Kara and Talat S Rahman Acetylene on Cu(111): imaging a molecular surface arrangement with a constantly rearranging tipYeming Zhu, Jonathan Wyrick, Kamelia D Cohen, Katie Marie Magnone, Connor Holzke, Daniel Salib, Quan Ma, Dezheng Sun and Ludwig Bartels Coulomb attraction during the carpet growth mode of NaClFriederike Matthaei, Sarah Heidorn, Konrad Boom, Cord Bertram, Ali Safiei, Jörg Henzl and Karina Morgenstern Molecular self-assembly on an insulating surface: interplay between substrate templating and intermolecular interactionsMarkus Kittelmann, Philipp Rahe and Angelika Kühnle Vertical manipulation of native adatoms on the InAs(111)A surfaceJ Yang, C Nacci, J Martínez-Blanco, K Kanisawa and S Fölsch Charge transfer between isomer domains on n+-doped Si(111)-2 × 1: energetic stabilizationR M Feenstra, G Bussetti, B Bonanni, A Violante, C Goletti, P Chiaradia, M G Betti and C Mariani Probing the properties of metal-oxide interfaces: silica films on Mo and Ru supportsLeonid Lichtenstein, Markus Heyde, Stefan Ulrich, Niklas Nilius

VLBA Teams With Optical Interferometer to Study Star's Layers

Science.gov (United States)

2007-05-01

Two of the World's Largest Interferometric Facilities Team-up to Study a Red Giant Star Using ESO's VLTI on Cerro Paranal and the VLBA facility operated by NRAO, an international team of astronomers has made what is arguably the most detailed study of the environment of a pulsating red giant star. They performed, for the first time, a series of coordinated observations of three separate layers within the star's tenuous outer envelope: the molecular shell, the dust shell, and the maser shell, leading to significant progress in our understanding of the mechanism of how, before dying, evolved stars lose mass and return it to the interstellar medium. S Orionis (S Ori) belongs to the class of Mira-type variable stars. It is a solar-mass star that, as will be the fate of our Sun in 5 billion years, is nearing its gloomy end as a white dwarf. Mira stars are very large and lose huge amounts of matter. Every year, S Ori ejects as much as the equivalent of Earth's mass into the cosmos. ESO PR Photo 25a/07 ESO PR Photo 25a/07 Evolution of the Mira-type Star S Orionis "Because we are all stardust, studying the phases in the life of a star when processed matter is sent back to the interstellar medium to be used for the next generation of stars, planets... and humans, is very important," said Markus Wittkowski, lead author of the paper reporting the results. A star such as the Sun will lose between a third and half of its mass during the Mira phase. S Ori pulsates with a period of 420 days. In the course of its cycle, it changes its brightness by a factor of the order of 500, while its diameter varies by about 20%. Although such stars are enormous - they are typically larger than the current Sun by a factor of a few hundred, i.e. they encompass the orbit of the Earth around the Sun - they are also distant and to peer into their deep envelopes requires very high resolution. This can only be achieved with interferometric techniques. ESO PR Photo 25b/07 ESO PR Photo 25b/07

2012 geothermal energy congress. Proceedings

International Nuclear Information System (INIS)

2012-01-01

); (15) GEOGRUND*: Transfer of the TCS process into the borehole (David Sauer); (16) 'Heat-in-place-density' - An example for the evaluation of the geothermal potential in Saarland (Hagen Deckert); (17) Experiences of the acidity stimulation of geothermal aquifers and plants (Markus Wolfgramm); (18) Geothermal Atlas for the depiction of possible utilization competitions between CCS and deep geothermy - Methodology and results (E. Suchi); (19) Development of a cooling system for geothermal bore hole probes (Benedict Holbein); (20) Geothermal energy in the context of international radiation protection recommendations (Sebastian Feige); (21) Innovative treatment of groundwater as a condition of an efficient air conditioning in buildings by utilization of near-surface geothermal energy (C. Meyer); (22) Preparation of planning maps for the utilization of near-surface geothermal energy with geo-physical methods (Reinhard Kirsch); (23) Deep geothermal probe Heubach - Progress of the project and facility planning by using an application example (David Kuntz); (24) Realistic numeric models for the simulation of potential geothermal reservoirs in the north-west German basin (Dorothea Reyer); (25) Monobore tracer test sensitivity compared with crack parameters and rock parameter: Lection Horstberg (Iulia Ghergut); (26) Infrastructure of fault zones in red sandstone of the Upper Rhine basin - Digestion analogue studies (Johanna F. Bauer); (27) Characterization of fault zones in shell limestone of the Upper Rhine basin - Digestion analogue studies (Silke Meier).

Research for energy optimized building. Status seminar; Forschung fuer Energieoptimiertes Bauen. Statusseminar

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-01

); (17) Quality assurance for geothermal probes for heating and cooling (Manfred Reuss, Markus Proell, Roland Koenigsdorff); (18) Phase change fluids for heat storage in the air conditioning of buildings (Stefan Gschwander, Peter Schossig); (19) Thermochemical storages for heating, air conditioning and dehumidification (Andreas Hauer); (20) A survey of solar storage applications (Klaus Vajen et al.); (21) Application of phase change materials (PCM) in the construction of wooden buildings in order to avoid an overheating in summer (Christoph Kempkes, Stephan Schlitzberger); (22) The air cross-flowed boulders storage - Innovation in the aeration of buildings (Mario Reichel, Ronny Stieber); (23) GeoTU6 - Utilization of geotheremal energy in tunnels in the areas of cities using the tram system tunnel Stuttgart-Fasanenhof (U69) as an example (Marcus Schneider et al.); (24) A simulation-based automation and optimization of operation (Ursula Eicker et al.); (25) Model-based operation analysis of buildings - Methods for the recognition of mistakes and optimization in the facility management (Christian Neumann, Dirk Jacob); (26) Optimization of operation of university buildings (Werner Jensch et al.); (27) EnBop - Energetic optimization of operation (Stefan Plesser, M. Norbert Fisch); (27) Monitoring at DVZ Barnim in Eberswalde (Tobias Haeusler); (28) Joint project: An energy optimized illumination at simultaneous improvement of the life quality using daylight and new lamp technology and series technology (Heinrich Kaase et al.).

Millennial oscillations in greenland dust and Eurasian Aeolian records - a paleosol-loess perspective (Hans Oeschger Medal Lecture)

Science.gov (United States)

Rousseau, Denis-Didier

2017-04-01

Greenland ice cores, and a critical study of their source variations, reconciles these records with those observed on the Eurasian continent. This allows demonstrating the link between European and Chinese loess sequences, dust records in Greenland, and variations of the North Atlantic sea ice extent. The sources of the emitted and transported dust material are variable and relate to different environments corresponding to present desert areas in Asia, but also hidden regions related to lower sea level stands, dry rivers, or zones close to the frontal moraines of the main Northern Hemisphere ice sheets in Europe. As a conclusion of this presentation, I address the short term past climatic changes as preserved in the continental eolian records, in line with the Hans Oeschger medal description. Furthermore one can anticipate such study to be at the origin of more sophisticated and elaborated investigations of millennial and sub-millennial continental climate variability on the Northern Hemisphere. The overview presented during this presentation would not have been possible without the help and close collaboration of many colleagues among whom are Niklas BOERS, Adriana SIMA, Anders SVENSSON, Matthias BIGLER, France LAGROIX, Samuel TAYLOR, Pierre ANTOINE, Christine HATTE, Michael GHIL, George KUKLA, Sigfus JOHNSEN, Markus FUCHS, Andreas LANG, Gilles BERGAMETTI, Beatrice MARTICORENA and Ludwig ZOELLER.

Digital Gaming for Improving the Functioning of People With Traumatic Brain Injury: Randomized Clinical Feasibility Study.

Science.gov (United States)

Välimäki, Maritta; Mishina, Kaisa; Kaakinen, Johanna K; Holm, Suvi K; Vahlo, Jukka; Kirjonen, Markus; Pekurinen, Virve; Tenovuo, Olli; Korkeila, Jyrki; Hämäläinen, Heikki; Sarajuuri, Jaana; Rantanen, Pekka; Orenius, Tage; Koponen, Aki

2018-03-19

. However, depression scores increased significantly between baseline and after 8 weeks and between baseline and after 3 months in the rehabilitative gaming group. No differences were found in patients' self-efficacy between the three measuring points in any of the groups. Participants did use the games (rehabilitation group: 93%, 27/29; entertainment group 100%, 29/29). Games were seen as a usable intervention (rehabilitation group: 70%, 14/29; entertainment group: 83%, 20/29). The rehabilitation group was less satisfied with the gaming intervention (68%, 13/29 vs 83%, 20/29), but they were more willing to use the game after the intervention period (76%, 16/29 vs 63%, 15/29). Total time spent on gaming during the intervention period was low (15.22 hour rehabilitation gaming group, 19.22 hour entertainment gaming group). We did not find differences between the groups in improvement in the outcome measures. The improvements in test performance by all three groups may reflect rehearsal effects. Entertainment gaming had elements that could be considered when rehabilitative games are designed for, implemented in, and assessed in larger clinical trials for persons with TBI. ClinicalTrials.gov NCT02425527; https://clinicaltrials.gov/ct2/show/NCT02425527 (Archived by WebCite at http://www.webcitation.org/6esKI1uDH). ©Maritta Välimäki, Kaisa Mishina, Johanna K Kaakinen, Suvi K Holm, Jukka Vahlo, Markus Kirjonen, Virve Pekurinen, Olli Tenovuo, Jyrki Korkeila, Heikki Hämäläinen, Jaana Sarajuuri, Pekka Rantanen, Tage Orenius, Aki Koponen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 19.03.2018.

From academy to industry

International Nuclear Information System (INIS)

Chatal, J.F.

2015-01-01

is necessary to have a proprietary ARC which has been successfully studied in preclinical studies and then in phase I and II trials in an indication covering a high number of patients. Prostate cancer can be such an indication. First the recently approved drugs for the treatment of patients with metastatic castrate-resistant cancer (mCRPC) leave a lot of space for improvement. Second, an antibody, directed to extra-cellular part of PSMA (J591) and labeled with lutetium-177, has been developed by Weill Cornell Medical College in the USA and has shown good tolerance and dose-dependent anti-tumor effect in phases I and II trials in mCRPC patients Based on these exciting results, ATLAB Pharma is now preparing a Phase III study. References: [1] Press OW, Palanca-Wessels M.C.; Selection of first-line therapy for advanced follicular lymphoma, J. Clin. Oncol. 2013 - 31: 1496- 1499; [2] Liersch, T.; Meller, J.; Kulle, B.; Behr, T.M.; Markus, P.; Langer, C., et al.; Phase II trial of carcinoembryonic antigen radioimmunotherapy with 131 I-labetuzumab after salvage resection of colorectal metastases in the liver: five-year safety and efficacy results, J. Clin. Oncol. 2005 - 23: 6763-70; [3] Tagawa, S.T.; Akhtar, N.H.; Osborne, J.; Christos, P.; Vallabhajosula, S.; Goldsmith, S.J.; Kahn, R.; Ecker, C.; Morris, M.J.; Milowsky, M.I.; Bander, N.H.; Nanus, D.M.; Phase II trial of 177 lutetium radiolabeled anti-PSMA antibody J591( 177 Lu-J591) for metastatic castrate-resistant prostate cancer (metCRPC): survival update and expansion cohort with bio-markers. ASCO 2013, Genitourinary cancer meeting, Orlando 14-16 February, 2013. (author)

Proceedings of the European Forum on Nuclear Waste governance

International Nuclear Information System (INIS)

2004-01-01

, general president, PURAM, Hungary, Bruno Lescoeur, director of the Energy branch, EDF, Irena Mele, strategic counselor, ARAO, Slovenia, Serge Perez, member of the national Bureau, FNME, CGT, Etienne Pochon, director of Patrimony and Cleaning up, CEA, Philippe Pradel, director of the sector Treatment-Recycling-Logistic, COGEMA, Olof Soederberg, president of the Fund dedicated to nuclear waste management, counsellor at KASAM, Sweden. 3 - Audition: Jean-Yves Le Deaut, deputy for Meurthe-et-Moselle, vice-president, OPECST. 4 - Debate with the audience 5 - Audition: David McCauley, senior policy advisor, Uranium and Radioactive Waste Division, Natural Resources, Government of Canada. 6 - Debate with the audience. 7 - Second round table: 'The partnership between stakeholders and local municipalities for a sustainable development on territories' (Moderator: Giles Chichester, member of the European Parliament, president European Foundation for Energy, president of ITRE commission of the European Parliament (UK)), Speaker: Bruno Sido, president of the General Council of Haute-Marne and senator, Discussants: Dominique Bourg, professor de philosophy and industrial ecology, University of Troyes, Eric Delhaye, spokesman, CAP 21, Robert Fernbach, mayor of Houdelaincourt, member of the CLIS Bureau, Markus Fritschi, head of repository projects, NAGRA, Switzerland, Patrick Juillard, director, Technopolis of Cherbourg Normandie, Jean-Marc Lambinon, president of Chamber of Commerce and Industry Haute-Marne, Jorge Lang-Lenton, director of communication, ENRESA, Spain, Rolf Linkohr, nuclear physician, honorary president of European Foundation for Energy, Germany, Christian Namy, president of the General Council of Meuse. 8 - Conclusions by Francois Lamoureux, general director of the Transport/ Energy Directorate General of the European Commission

PV-HYBRID and MINI-GRID. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

design and validation of PV-hybrid sysem technology for rural electrification programmes in remote areas of Europe (Xavier Valive); (17) Analysis of inverter-controlled Island grids - transient simulations with ATP-EMTP and PowerFactory (Martin Braun); (18) Design of a PV-diesel hybrid energy system (William Lawrance); (19) Hybrid storage systems in PV stand alone applications impact on sizing and performance (Julien Labbe); (20) Sizing and analysis of a small hydro PV hybrid system for the rural electrification in developing countries (Joseph Kenfack); (21) Identification of dynamic equivalents for microgrids with high penetration of solar energy using ANNs (F.O. Resende); (22) Constructing village PV hybrid power systems on a wide-scale in Western China: Experience gained (Henrik Bindner); (23) Experiences with large-scale construction of PH hybrid village power systems in Western China (Winfried Klinghammer); (24) A detailed data based analysis of the behaviour of a 10+5+20 KW wind-PV-diesel hybrid sysem (Luis M. Arribas); (25) PV hybrid village electrification in French Guyana (Christian Dumbs); (26) Energy consumption patterns in village PV-diesel-hybrid systems (Javier Munoz); (27) From Subag to Ponelo hybrid photovoltaic-diesel system in Indonesia, lessons learned (Adjat Sudradjat); (28) PV diesel hybrid system in rural Africa - an inter-disciplinary approach (Markus Landau); (29) Making PV-diesel hybrids and PV or wind mini-grids sustainable in remote developing country sites: the Nabouwalu case (Philippe Veyan); (30) Mini-grid for an isolated island sandwip in Bangladesh (B.K. Bala).

Book Reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

1999-07-01

-Arlene Torres, Jean P. Peterman, Telling their stories: Puerto Rican Women and abortion. Boulder CO: Westview Press, 1996. ix + 112 pp. -Trevor W. Purcell, Philip Sherlock ,The story of the Jamaican People. Kingston: Ian Randle; Princeton: Markus Wiener, 1998. xii + 434 pp., Hazel Bennett (eds -Howard Fergus, Donald Harman Akenson, If the Irish ran the world: Montserrat, 1630-1730. Liverpool: Liverpool University Press, 1997. xii + 273 pp. -John S. Brierley, Lawrence S. Grossman, The political ecology of bananas: Contract farming, peasants, and agrarian change in the Eastern Caribbean. Chapel Hill: University of North Carolina Press, 1998. xx + 268 pp. -Mindie Lazarus-Black, Jeannine M. Purdy, Common law and colonised peoples: Studies in Trinidad and Western Australia. Aldershot, UK: Ashgate Dartmouth, 1997. xii + 309. -Stephen Slemon, Barbara Lalla, Defining Jamaican fiction: Marronage and the discourse of survival. Tuscaloosa: University of Alabama Press, 1996. xi + 224 pp. -Stephen Slemon, Renu Juneja, Caribbean transactions: West Indian culture in literature. -Sue N. Greene, Richard F. Patteson, Caribbean Passages: A critical perspective on new fiction from the West Indies. Boulder CO: Lynne Rienner Publishers, 1998. ix + 187 pp. -Harold Munneke, Ivelaw L. Griffith ,Democracy and human rights in the Caribbean. Boulder CO: Westview Press, 1997. vii + 278 pp., Betty N. Sedoc-Dahlberg (eds -Francisco E. Thoumi, Ivelaw Lloyd Griffith, Drugs and security in the Caribbean: Sovereignty under seige. University Park: Penn State University Press, 1997. xx + 295 pp. -Michiel Baud, Eric Paul Roorda, The dictator next door: The good neighbor policy and the Trujillo regime in the Dominican republic, 1930-1945. Durham NC: Duke University Press, 1998. xii + 337 pp. -Peter Mason, Wim Klooster, The Dutch in the Americas 1600-1800. Providence RI: The John Carter Brown Library, 1997. xviii + 101 pp. -David R. Watters, Aad H. Versteeg ,The archaeology of Aruba: The Tanki Flip site

Páginas iniciais

Directory of Open Access Journals (Sweden)

Ficha catalográfica e sumário bilíngue

2013-12-01

�BLICO EM GOIÂNIA – GO – BRASIL QUALITY AND INNOVATION IN PUBLIC TRANSPORTATION SERVICE IN GOIANIA – GO – BRAZIL Maria Regina Silva Lima Bento Alves Costa Filho Cesar Ricardo Maia Vasconcelos CRESCIMENTO OU MANUTENÇÃO DA POSIÇÃO: O DILEMA DOS GESTORES DE UMA INDÚSTRIA DE PLÁSTICOS DA SERRA GAÚCHA GROWTH OR MAINTENANCE OF THE POSITION: THE DILEMMA OF THE MANAGERS OF A PLASTICS INDUSTRY SERRA GAUCHA Julio Cesar Ferro de Guimarães Eliana Andréa Severo Sylvia Maria Azevedo Roesch Pelayo Munhoz Olea Eric Charles Henri Dorion ESTRATÉGIA E COMUNICAÇÃO COM O MERCADO. PERCEPÇÃO DOS GESTORES DAS INSTITUIÇÕES DE ENSINO SUPERIOR SOBRE AS AÇÕES DE RESPONSABILIDADE SOCIAL NA PERSPECTIVA DO MÉTODO FENOMENOLÓGICO STRATEGY AND COMMUNICATION WITH THE MARKET. PERCEPTION OF MANAGERS OF INSTITUTIONS OF HIGHER EDUCATION ON THE CORPORATE SOCIAL RESPONSIBILITY IN THE PHENOMENOLOGICAL METHOD VIEW Roberto Bazanini Ademir Antonio Ferreira Homero Leoni Bazanini Rosalina Florindo da Silva REGIONAL DEVELOPMENT POLICY IN BRAZIL: A REVIEW OF EVALUATION LITERATURE POLÍTICA DE DESENVOLVIMENTO REGIONAL NO BRASIL: UMA REVISÃO DA LITERATURA SOBRE AVALIAÇÃO Guilherme Mendes Resende FLORESTAS E PARTICIPAÇÃO COMO VETORES DO DESENVOLVIMENTO REGIONAL: REFLEXÕES SOBRE OS CASOS ACRE E RIO GRANDE DO SUL FORESTRY AND CIVIC PARTICIPATION AS DRIVERS OF REGIONAL DEVELOPMENT: ANALYSIS OF THE CASES ACRE AND RIO GRANDE DO SUL Markus Erwin Brose A IMPORTÂNCIA DA INTERDISCIPLINARIDADE PARA COMPREENSÃO DAS QUESTÕES AMBIENTAIS THE IMPORTANCE OF INTERDISCIPLINARITY FOR UNDERSTADING OF THE ENVIRONMENTAL SUBJETCTS Cidonea Machado Deponti PROJETOS DE VIDA, MOBILIDADE E METRÓPOLE: AS TRAJETÓRIAS DE JOVENS ADULTOS NO CONTEXTO INTERNACIONAL LIFE PROJECTS, MOBILITY AND METROPOLIS : YOUNG ADULTS’ IN THE INTERNATIONAL CONTEXT Grazielle Betina Brandt Serge Côté

Influence of plant productivity over variability of soil respiration: a multi-scale approach

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Curiel Yuste, J.

2009-04-01

general controlled by the seasonality of substrate supply by plants (via photosynthates translocation and/or litter) to soil. Although soil temperature and soil moisture exert a strong influence over the variation in SR, our results indicates that substrate supply by plant activity could exert a more important than previously expected role in the variability of soil respiration. 1. CREAF (Centre de Recerca Ecológica i Aplicacions Forestals), Unitat d'Ecofisiologia i Canvi Global CREAF-CEAB-CSIC, BELLATERRA (Barcelona), Spain (j.curiel@creaf.uab.es) 2. University of Antwerp (UA), Antwerp, Belgium (ivan.janssens@ua.ac.be) 3. Institute of Ecology, University of Innsbruck, Innsbruck, Austria (michael.bahn@uibk.ac.at) 4. UMR Ecologie et Ecophysiologie Forestières, Centre INRA de Nancy, France (longdoz@nancy.inra.fr) 5. ESPM, University of Calicornia at Berkeley, Berkeley, CA, US (baldocchi@nature.berkeley.edu) 6. The Woods Hole Research Center, Falmouth, USA (edavidson@whrc.org) 7. Max-Planck-Institute for Biogeochemistry, Jena, Germany (markus.reichstein@bgc-jena.mpg.de) 8. Institute of Systems Biology and Ecology, Academy of Sciences of the Czech Republic, Czech Republic (manuel@brno.cas.cz) 9. Università degli studi della Tuscia, Viterbo, Italy (arriga@unitus.it) 10. Laurence Berkeley lab, Berkeley, CA, USA (mstorn@lbl.gov) 11. Gembloux Agricultural University, Gembloux, Belgium (aubinet.m@fsagx.ac.be) 12. Fundacion CEAM(Centro de Estudios Ambientales del Mediterráneo), Valencia, Spain (arnaud@ceam.es) 13. Institute of Hydrology and Meteorology, Technische Universität Dresden, Pienner, Germany (gruenwald@forst.tu-dresden.de) 14. Department of Environmental Sciences, Second University of Naples, Caserta, Italy (ilaria.inglima@unina2.it) 15. CNRS-CEFE Montpellier, France (Laurent.MISSON@cefe.cnrs.fr) 16. Agenzia Provinciale per l'Ambiente, Bolzano, Italy (leonar@inwind.it) 17. University of Helsinki Department of Forest Ecology, Helsinki, Finland (jukka

COST Action MP0806 'Particles in Turbulence': International Conference on Fundamentals, Experiments, Numeric and Applications

Science.gov (United States)

Abel, Markus; Bodenschatz, Eberhard; Toschi, Federico

2011-12-01

also like to thank the students from Potsdam University for their exquisite help. We are very thankful to Anita Peeters for her unwavering support and help in the organization of this particular event, as well as, for the efforts ensuring the smooth running of the COST Action 'Particles in turbulence'. Markus Abel, Eberhard Bodenschatz, Federico Toschi The PDF files of the conference program and conference poster are attached.

Über dieses Heft

Directory of Open Access Journals (Sweden)

Editors / Herausgeber

2013-06-01

Full Text Available Bilder, audiovisuelle Medien, elektronische Medien, World Wide Web: Das Erzählen vollzieht sich mittlerweile in vielfältigen Formen. Der intensive Gebrauch von neuen Medien in unterschiedlichen Zusammenhängen begegnet, überlagert und vermischt sich mit der Rezeption traditioneller literarischer Medien, die nach wie vor weit verbreitet sind. Für die Erzählforschung ergibt sich aus der veränderten kulturellen Praxis eine Vielzahl von Folgen. Die vorliegende Ausgabe von DIEGESIS soll einen Eindruck davon vermitteln. So rückt etwa ein Korpus in den Vordergrund, das lange Zeit eine Randexistenz führte: Erzählungen, die nicht oder nicht ausschließlich durch Sprache vermittelt werden, und solche, die nicht mehr nur die Kulturtechnik des Lesens und Schreibens voraussetzen. Andere Techniken, andere Gesten begleiten den Umgang mit diesen Erzählungen, und diese Differenz wird an denjenigen Stellen besonders deutlich, wo unterschiedliche Medien ineinander verschachtelt sind. Die Erzeugung von Komplexität durch intermediale Relationen charakterisiert dieses neue Korpus und öffnet für die Erzählforschung neue Arbeitsfelder. Gerade die markanten Medienwechsel, die mit der Vermarktung erfolgreicher Stoffe – als Roman, als Film, als Computerspiel, als Comic, als YouTube-Parodie – einhergehen, werfen die doppelte Frage auf, was in diesen Varianten das gemeinsame narrative Substrat, und was hingegen medienspezifische Erzählverfahren sind. Der ersten Perspektive folgt in der vorliegenden Ausgabe Matthias Brütsch mit einer kritischen Prüfung transmedialer Narrativitätsvergleiche; die zweite entfalten Sebastian Armbrusts Beitrag über Komplexität in bekannten Fernsehserien wie House und The Wire und Markus Kuhns Analyse der narrativen Funktion der Handkamera als spezifischem Verfahren in Spielfilmen und fiktionalen Internetclips. Selbstverständlich haben sich auch bestehende Kategorien der Erzählforschung unter dem Eindruck gewandelt, dass

PREFACE: 5th International Workshop on Top Quark Physics (TOP2012)

Science.gov (United States)

Salamanna, G.; Boisvert, V.; Cerrito, L.; Khan, A.; Moretti, S.; Owen, M.; Schwanenberger, C.

2013-07-01

resonances in the boosted top regime were also provided. Finally, a set of dedicated talks on the interplay between the top sector and other hot subjects, like the Higgs and SUSY, were given both at the theory and experimental level. Furthermore, ad hoc student sessions were organized to allow younger colleagues to pose questions to the senior experts in the field and contribute with their more recent studies. The conference has been a definitive success, not just scientifically: about 130 participants from all over the world created a collegiate spirit which culminated in the social events at Winchester Hall below King Arthur's table; and in a cosy 16th century barn for the social dinner. The Local Organizing Committee would like to thank all participants, and in particular the speakers, for their high level contributions to TOP 2012 and for making this a very fruitful and pleasant time together. We conclude by wishing the Organizing Committee of TOP 2013 all the best for a successful conference. We look forward to seeing everyone in Germany in 2013. Giuseppe Salamanna Local Organizing Committee London, June 2013 Local Organising Committee Veronique Boisvert (Chair, Royal Holloway, University of London) Lucio Cerrito (Queen Mary, University of London) Akram Khan (Brunel University, London) Stefano Moretti (University of Southampton) Mark Owen (University of Manchester) Giuseppe Salamanna (Queen Mary, University of London) Christian Schwanenberger (University of Manchester) International Advisory Committee Roberto Tenchini (INFN, Pisa) Martine Bosman (IFAE, Barcelona) Michelangelo Mangano (CERN) Scott Willenbrock (University of Illinois, Urbana) Werner Bernreuther (RWTH, Aachen) Jorgen D'Hondt (VUB, Brussels) Antonio Onofre (LIP, University Minho) Fabio Maltoni (UCL, Louvain) Eric Laenen (NIKHEF) Fabrizio Margaroli (INFN, Roma 1) Juan Antonio Aguilar Saavedra (University of Granada) Yvonne Peters (University of Manchester) Roberto Chierici (CERN) Markus Cristinziani

Book Reviews

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Redactie KITLV

2002-07-01

Full Text Available -Alan L. Karras, Lauren A. Benton, Law and colonial cultures: Legal regimes in world history, 1400-1900. Cambridge: Cambridge University Press, 2002. xiii + 285 pp. -Sidney W. Mintz, Douglass Sullivan-González ,The South and the Caribbean. Jackson: University Press of Mississippi, 2001. xii + 208 pp., Charles Reagan Wilson (eds -John Collins, Peter Redfield, Space in the tropics: From convicts to rockets in French Guiana. Berkeley: University of California Press, 2000. xiii + 345 pp. -Vincent Brown, Keith Q. Warner, On location: Cinema and film in the Anglophone Caribbean. Oxford: Macmillan, 2000. xii + 194 pp. -Ann Marie Stock, Jacqueline Barnitz, Twentieth-century art of Latin America. Austin: University of Texas Press, 2001. 416 pp. -Ineke Phaf, J.J. Oversteegen, Herscheppingen: De wereld van José Maria Capricorne. Emmastad, Curacao: Uitgeverij ICS Nederland/Curacao, 1999. 168 pp. -Halbert Barton, Frances R. Aparicio, Listening to Salsa: Gender, latin popular music, and Puerto Rican cultures. Hanover NH: Wesleyan University Press, 1998. xxi + 290 pp. -Pedro Pérez Sarduy, John M. Kirk ,Culture and the Cuban revolution: Conversations in Havana. Gainesville: University Press of Florida, 2001. xxvi + 188 pp., Leonardo Padura Fuentes (eds -Luis Martínez-Fernández, Damián J. Fernández, Cuba and the politics of passion. Austin: University of Texas Press, 2000. 192 pp. -Eli Bartra, María de Los Reyes Castillo Bueno, Reyita: The life of a black Cuban woman in the twentieth century. Durham NC: Duke University Press, 2000. 182 pp. -María del Carmen Baerga, Felix V. Matos Rodríguez, Women and urban change in San Juan, Puerto Rico, 1820-1868. Gainesville: University Press of Florida, 1999. xii + 180 pp. [Reissued in 2001 as: Women in San Juan, 1820-1868. Princeton NJ: Markus Weiner Publishers.] -Kevin A. Yelvington, Winston James, Holding aloft the banner of Ethiopa: Caribbean radicalism in early twentieth-century America. New York: Verso, 1998

Book Reviews

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Redactie KITLV

2003-01-01

leadership, legitimacy and populist politics. Kingston: Ian Randle; Boulder CO: Lynne Rienner, 2001. xvi + 264 pp. -Bill Maurer, Cynthia Weber, Faking it: U.S. Hegemony in a 'post-phallic' era. Minneapolis: University of Minnesota Press, 1999. xvi + 151 pp. -Kelvin Santiago-Valles, Christina Duffy Burnett ,Foreign in a domestic sense: Puerto Rico, American expansion, and the constitution. Durham NC: Duke University Press, 2001. xv + 422 pp., Burke Marshall (eds -Rubén Nazario, Efrén Rivera Ramos, The legal construction of identity: The judicial and social legacy of American colonialism in Puerto Rico. Washington DC: American Psychological Association, 2000. 275 pp. -Marc McLeod, Louis A. Pérez, Jr., Winds of change: Hurricanes and the transformation of nineteenth-century Cuba. Chapel Hill: University of North Carolina Press, 2001. x + 199 pp. -Jorge L. Giovannetti, Fernando Martínez Heredia ,Espacios, silencios y los sentidos de la libertad: Cuba entre 1878 y 1912. Havana: Ediciones Unión, 2001. 359 pp., Rebecca J. Scott, Orlando F. García Martínez (eds -Reinaldo L. Román, Miguel Barnet, Afro-Cuban religions. Princeton NJ: Markus Wiener Publishers, 2001. 170 pp. -Philip W. Scher, Hollis 'Chalkdust' Liverpool, Rituals of power and rebellion: The carnival tradition in Trinidad and Tobago, 1763-1962. Chicago: Research Associates School Times Publications and Frontline distribution international, 2001. xviii + 518 pp. -Asmund Weltzien, David Griffith ,Fishers at work, workers at sea: A Puerto Rican journey through labor and refuge. Philadelphia PA: Temple University Press, 2002. xiv + 265 pp., Manuel Valdés Pizzini (eds -Riva Berleant-Schiller, Eudine Barriteau, The political economy of gender in the twentieth-century Caribbean. New York: Palgrave, 2001. xvi + 214 pp. -Edward Dew, Rosemarijn Hoefte ,Twentieth-century Suriname: Continuities and discontinuities in a new world society. Kingston: Ian Randle; Leiden: KITLV Press, 2001. xvi + 365 pp., Peter Meel (eds -Joseph

ASPEK PENEGAKAN KODE ETIK HAKIM DALAM MEWUJUDKAN KEKUASAAN KEHAKIMAN YANG BERMARTABAT DAN BERINTEGRITAS

Directory of Open Access Journals (Sweden)

Heni Hendrawati

2016-03-01

Full Text Available Penulisan karya tulis ilmiah ini dilatarbelakangi oleh munculnya isu-isu negatif terkait penegakkan kode etik hakim dalam mewujudkan kekuasaan kehakiman yang bermartabat dan berintegritas. Isu-isu negatif itu antara lain terdapat fenomena tentang korupsi peradilan (judicial corruption dalam bentuk berbagai perilaku tercela (permainan kotor seperti penyuapan, transaksi perkara, calo perkara, makelar kasus (markus, pemerasan, jual beli putusan, dan sebagainya.  Padahal untuk menegakkan supremasi hukum adalah dengan menegakkan etika, profesionalisme serta disiplin terutama oleh profesi hakim. Metode penelitian yang digunakan adalah yuridis normatif, yaitu penelitian yang mengkaji peraturan perundang-undangan yang berlaku terhadap permasalahan yang dibahas. Jenis penelitian dalam penulisan karya tulis ilmiah ini adalah kepustakaan (library research yang menggunakan bahan hukum primer yaitu  Undang-Undang Nomor 48 Tahun 2009 Tentang Kekuasaan Kehakiman , Surat Keputusan Bersama Ketua Mahkamah Agung Republik Indonesia dan Ketua Komisi Yudisial Republik Indonesia Nomor: 047/KMA/SKB/IV/2009 -02/SKB/P.KY/IV/2009 Tentang Kode Etik dan Pedoman Perilaku Hakim, serta Peraturan Bersama Ketua Mahkamah Agung Republik Indonesia Dan Ketua Komisi Yudisial Republik Indonesia Nomor : 02/PB/MA/IX/2012- 02/PB/P.KY/09/2012 Tentang Panduan Penegakan Kode Etik Dan Pedoman Perilaku Hakim. Adapun bahan hukum sekunder berupa jurnal hukum, buku-buku, artikel hukum ilmiah  yang terkait dengan rumusan permasalahan penelitian. Sifat penelitian yang digunakan adalah deskriptif yaitu memberikan gambaran bagaimana implementasi peraturan perundang-undangan tentang kode etik hakim untuk mewujudkan hakim yang bermartabat dan berintegritas. Pendekatan penelitian yang digunakan adalah  pendekatan perundang-undangan (statute approach pendekatan sejarah (historical approach, pendekatan kasus (case approach.  Pendekatan perundang-undangan  terkait dengan upaya untuk mewujudkan hakim

Book Reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

2004-07-01

pp., Candida F. Jaquez (eds -Jorge Pérez Rolón, Maya Roy, Cuban Music. London: Latin America Bureau/Princeton NJ: Markus Wiener Publishers, 2002. ix + 246 pp. -Bettina M. Migge, Gary C. Fouse, The story of Papiamentu: A study in slavery and language. Lanham MD: University Press of America, 2002. x + 261 pp. -John M. McWhorter, Bettina Migge, Creole formation as language contact: the case of the Suriname creoles. Amsterdam: John Benjamins, 2003. xii + 151 pp.

PREFACE: 16th Nordic Semiconductor Meeting

Science.gov (United States)

Pétur Gíslason, Hafliði; Guðmundsson, Viðar

1994-01-01

including both basic and applied physics was also organized. Most of the oral sessions included an invited lecture. The invited speakers were all of high international class, five of them working in the Nordic countries, Sami Franssila, Finland, Jostein Grepstad, Norway, Jam Hvam, Denmark, Erik Janzén and Lars Samuelson, Sweden. The other five represented a wider geographical spread, Klaus von Klitzing and Detlef Heitmann, Germany, Gordon Davies, United Kingdom, Markus Büttiker and Chris Palmstrøm, U.S.A. Attendees from China, Japan, Switzerland, the Netherlands and Lithuania also participated in the conference. In addition to the invited lectures some 100 oral papers and 25 posters were contributed. Another novelty of the conference is the fact that the proceedings of the conference are being published in a refereed journal. These proceedings contain all the invited and contributed papers the authors of which complied with the deadline of submission of the manuscripts. The editors paid special attention to prompt publication of the proceedings in order to promote the actuality of the results presented at the conference. Therefore, the deadline was strict, all of the papers were refereed during the conference. Changes suggested by the referees were either made at Laugarvatn or within three weeks from the conference. We are grateful to the international crowd of session chairmen who assumed the task of refereeing the papers, either themselves or with the help of colleagues. Without their impressive qualifications this procedure would not have been as reliable as the quality of the papers deserved. We also want to thank the editorial staff of Physica Scripta for their help and cooperation. It is our hope that the 16th Nordic Semiconductor Meeting succeeded in keeping the tradition of a popular conference series at the same time as mowing slightly the emphasis which may strengthen future meetings. Time will tell. In the meantime, we thank all the participants for their

Book Reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

2000-07-01

: The Press University of the West Indies, 1998. xviii + 152 pp. -Kris Lane, Hans Turley, Rum, sodomy, and the lash: Piracy, sexuality, and masculine identity. New York: New York University Press, 1999. lx + 199 pp. -Jonathan Schorsch, Eli Faber, Jews, slaves, and the slave trade: Setting the record straight. New York: New York University Press, 1998. xvii + 367 pp. -Bonham C. Richardson, Bridget Brereton ,The Colonial Caribbean in transition: Essays on postemancipation social and cultural history. Barbados: The Press University of the West Indies; Gainesville: University Press of Florida, 1999. xxiii + 319 pp., Kevin A. Yelvington (eds -Ransford W. Palmer, Thomas Klak, Globalization and neoliberalism: The Caribbean context. New York: Rowman and Littlefield, 1998. xxiv + 319 pp. -Susan Saegert, Robert B. Potter ,Self-help housing, the poor, and the state in the Caribbean. Knoxville: University of Tennessee Press, 1997. xiv + 299 pp., Dennis Conway (eds -Peter Redfield, Michèle-Baj Strobel, Les gens de l'or: Mémoire des orpailleurs créoles du Maroni. Petit-Bourg, Guadeloupe: Ibis Rouge, 1998. 400 pp. -Donald R. Hill, Louis Regis, The political calypso: True opposition in Trinidad and Tobago 1962-1987. Gainesville: University Press of Florida, 1999. xv + 277 pp. -A. James Arnold, Christiane P. Makward, Mayotte Capécia ou l'aliénation selon Fanon. Paris: Karthala, 1999. 230 pp. -Chris Bongie, Celia M. Britton, Edouard Glissant and postcolonial theory: Strategies of language and resistance. Charlottesville: University Press of Virginia, 1999. xiv + 224 pp. -Chris Bongie, Anne Malena, The negotiated self: The dynamics of identity in Francophone Caribbean narrative. New York: Peter Lang, 1999. x + 192 pp. -Catherine A. John, Kathleen M. Balutansky ,Caribbean creolization: Reflections on the cultural dynamics of language, literature, and identity., Marie-Agnès Sourieau (eds -Leland Ferguson, Jay B. Haviser, African sites archaeology in the Caribbean. Princeton NJ: Markus

Book Reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

2004-01-01

Full Text Available -Chuck Meide, Kathleen Deagan ,Columbus's outpost among the Taínos: Spain and America at La Isabela, 1493-1498. New Haven CT: Yale University Press, 2002. x + 294 pp., José María Cruxent (eds -Lee D. Baker, George M. Fredrickson, Racism: A short history. Princeton NJ: Princeton University Press, 2002. x + 207 pp. -Evelyn Powell Jennings, Sherry Johnson, The social transformation of eighteenth-century Cuba. Gainesville: University Press of Florida, 2001. x + 267 pp. -Michael Zeuske, J.S. Thrasher, The island of Cuba: A political essay by Alexander von Humboldt. Translated from Spanish with notes and a preliminary essay by J.S. Thrasher. Princeton NJ: Markus Wiener; Kingston: Ian Randle, 2001. vii + 280 pp. -Matt D. Childs, Virginia M. Bouvier, Whose America? The war of 1898 and the battles to define the nation. Westport CT: Praeger, 2001. xi + 241 pp. -Carmelo Mesa-Lago, Antonio Santamaría García, Sin azúcar no hay país: La industria azucarera y la economía cubana (1919-1939. Seville: Consejo Superior de Investigaciones Científicas, Universidad de Sevilla y Diputación de Sevilla, 2001. 624 pp. -Charles Rutheiser, Joseph L. Scarpaci ,Havana: Two faces of the Antillean Metropolis. Chapel Hill: University of North Carolina Press, 2002. x + 437 pp., Roberto Segre, Mario Coyula (eds -Thomas Neuner, Ottmar Ette ,Kuba Heute: Politik, Wirtschaft, Kultur. Frankfurt am Main, Germany: Vervuert, 2001. 863 pp., Martin Franzbach (eds -Mark B. Padilla, Emilio Bejel, Gay Cuban nation. Chicago: University of Chicago Press, 2001. xxiv + 257 pp. -Mark B. Padilla, Kamala Kempadoo, Sun, sex, and gold: Tourism and sex work in the Caribbean. New York: Rowman & Littlefield, 1999. viii + 356 pp. -Jane Desmond, Susanna Sloat, Caribbean dance from Abakuá to Zouk: How movement shapes identity. Gainesville: University Press of Florida, 2002. xx + 408 pp. -Karen Fog Olwig, Nina Glick Schiller ,Georges woke up laughing: Long-distance nationalism and the

Book Reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

1999-01-01

+ 297 pp. -Roger D. Abrahams, Joseph Roach, Cities of the dead: Circum-Atlantic performance. New York NY: Columbia University Press, 1996. xiii + 328 pp. -George Mentore, Peter A. Roberts, From oral to literate culture: Colonial experience in the English West Indies. Kingston, Jamaica: The Press University of the West Indies, 1997. xii + 301 pp. -Emily A. Vogt, Howard Johnson ,The white minority in the Caribbean. Princeton NJ: Markus Wiener, 1998. xvi + 179 pp., Karl Watson (eds -Virginia Heyer Young, Sheryl L. Lutjens, The state, bureaucracy, and the Cuban schools: Power and participation. Boulder CO: Westview Press, 1996. xiii + 239 pp.

PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2010)

Science.gov (United States)

Lin, Simon C.; Shen, Stella; Neufeld, Niko; Gutsche, Oliver; Cattaneo, Marco; Fisk, Ian; Panzer-Steindel, Bernd; Di Meglio, Alberto; Lokajicek, Milos

2011-12-01

, as well as two banquets held at the Grand Hotel and Grand Formosa Regent in Taipei. The next CHEP conference will be held in New York, the United States on 21-25 May 2012. We would like to thank the National Science Council of Taiwan, the EU ACEOLE project, commercial sponsors, and the International Advisory Committee and the Programme Committee members for all their support and help. Special thanks to the Programme Committee members for their careful choice of conference contributions and enormous effort in reviewing and editing about 340 post conference proceedings papers. Simon C Lin CHEP 2010 Conference Chair and Proceedings Editor Taipei, Taiwan November 2011 Track Editors/ Programme Committee Chair Simon C Lin, Academia Sinica, Taiwan Online Computing Track Y H Chang, National Central University, Taiwan Harry Cheung, Fermilab, USA Niko Neufeld, CERN, Switzerland Event Processing Track Fabio Cossutti, INFN Trieste, Italy Oliver Gutsche, Fermilab, USA Ryosuke Itoh, KEK, Japan Software Engineering, Data Stores, and Databases Track Marco Cattaneo, CERN, Switzerland Gang Chen, Chinese Academy of Sciences, China Stefan Roiser, CERN, Switzerland Distributed Processing and Analysis Track Kai-Feng Chen, National Taiwan University, Taiwan Ulrik Egede, Imperial College London, UK Ian Fisk, Fermilab, USA Fons Rademakers, CERN, Switzerland Torre Wenaus, BNL, USA Computing Fabrics and Networking Technologies Track Harvey Newman, Caltech, USA Bernd Panzer-Steindel, CERN, Switzerland Antonio Wong, BNL, USA Ian Fisk, Fermilab, USA Niko Neufeld, CERN, Switzerland Grid and Cloud Middleware Track Alberto Di Meglio, CERN, Switzerland Markus Schulz, CERN, Switzerland Collaborative Tools Track Joao Correia Fernandes, CERN, Switzerland Philippe Galvez, Caltech, USA Milos Lokajicek, FZU Prague, Czech Republic International Advisory Committee Chair: Simon C. Lin , Academia Sinica, Taiwan Members: Mohammad Al-Turany , FAIR, Germany Sunanda Banerjee, Fermilab, USA Dario Barberis, CERN

PREFACE: Ultrathin layers of graphene, h-BN and other honeycomb structures Ultrathin layers of graphene, h-BN and other honeycomb structures

Science.gov (United States)

Geber, Thomas; Oshima, Chuhei

2012-08-01

Kusunoki Mechanical exfoliation of epitaxial graphene on Ir(111) enabled by Br2 intercalationCharlotte Herbig, Markus Kaiser, Nedjma Bendiab, Stefan Schumacher, Daniel F Förster, Johann Coraux, Klaus Meerholz, Thomas Michely and Carsten Busse Low energy electron microscopy and photoemission electron microscopy investigation of grapheneK L Man and M S Altman Periodic overlayers and moiré patterns: theoretical studies of geometric propertiesKlaus Hermann Silicene structures on silver surfacesHanna Enriquez, Sébastien Vizzini, Abdelkader Kara, Boubekeur Lalmi and Hamid Oughaddou Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopyS Koch, M Langer, S Kawai, E Meyer and Th Glatzel Probing the electronic structure and optical response of a graphene quantum disk supported on monolayer grapheneWu Zhou, Stephen J Pennycook and Juan-Carlos Idrobo Multi-oriented moiré superstructures of graphene on Ir(111): experimental observations and theoretical modelsLei Meng, Rongting Wu, Lizhi Zhang, Linfei Li, Shixuan Du, Yeliang Wang and H-J Gao The physics of epitaxial graphene on SiC(0001)H Kageshima, H Hibino and S Tanabe

PREFACE: Semiconducting oxides Semiconducting oxides

Science.gov (United States)

Catlow, Richard; Walsh, Aron

2011-08-01

their help in producing this special section. We hope that it conveys some of the excitement and significance of the field. Semiconducting oxides contents Chemical bonding in copper-based transparent conducting oxides: CuMO2 (M = In, Ga, Sc) K G Godinho, B J Morgan, J P Allen, D O Scanlon and G W Watson Electrical properties of (Ba, Sr)TiO3 thin films with Pt and ITO electrodes: dielectric and rectifying behaviourShunyi Li, Cosmina Ghinea, Thorsten J M Bayer, Markus Motzko, Robert Schafranek and Andreas Klein Orientation dependent ionization potential of In2O3: a natural source for inhomogeneous barrier formation at electrode interfaces in organic electronicsMareike V Hohmann, Péter Ágoston, André Wachau, Thorsten J M Bayer, Joachim Brötz, Karsten Albe and Andreas Klein Cathodoluminescence studies of electron irradiation effects in n-type ZnOCasey Schwarz, Yuqing Lin, Max Shathkin, Elena Flitsiyan and Leonid Chernyak Resonant Raman scattering in ZnO:Mn and ZnO:Mn:Al thin films grown by RF sputteringM F Cerqueira, M I Vasilevskiy, F Oliveira, A G Rolo, T Viseu, J Ayres de Campos, E Alves and R Correia Structure and electrical properties of nanoparticulate tungsten oxide prepared by microwave plasma synthesisM Sagmeister, M Postl, U Brossmann, E J W List, A Klug, I Letofsky-Papst, D V Szabó and R Würschum Charge compensation in trivalent cation doped bulk rutile TiO2Anna Iwaszuk and Michael Nolan Deep level transient spectroscopy studies of n-type ZnO single crystals grown by different techniquesL Scheffler, Vl Kolkovsky, E V Lavrov and J Weber Microstructural and conductivity changes induced by annealing of ZnO:B thin films deposited by chemical vapour depositionC David, T Girardeau, F Paumier, D Eyidi, B Lacroix, N Papathanasiou, B P Tinkham, P Guérin and M Marteau Multi-component transparent conducting oxides: progress in materials modellingAron Walsh, Juarez L F Da Silva and Su-Huai Wei Thickness dependence of the strain, band gap and transport properties of

PREFACE: Complex dynamics of fluids in disordered and crowded environments Complex dynamics of fluids in disordered and crowded environments

Science.gov (United States)

Coslovich, Daniele; Kahl, Gerhard; Krakoviack, Vincent

2011-06-01

T Fischer and R L C Vink Lennard-Jones binary mixture in disordered matrices: exploring the mode coupling scenario at increasing confinement P Gallo and M Rovere Static and dynamic contributions to anomalous chain dynamics in polymer blends Marco Bernabei, Angel J Moreno and J Colmenero Anomalous transport of a tracer on percolating clusters Markus Spanner, Felix Höfling, Gerd E Schröder-Turk, Klaus Mecke and Thomas Franosch Long-wavelength anomalies in the asymptotic behavior of mode-coupling theory S K Schnyder, F Höfling, T Franosch and Th Voigtmann Dynamic arrest of colloids in porous environments: disentangling crowding and confinement Jan Kurzidim, Daniele Coslovich and Gerhard Kahl Slow dynamics, dynamic heterogeneities, and fragility of supercooled liquids confined in random media Kang Kim, Kunimasa Miyazaki and Shinji Saito

EDITORIAL: King of the elements? King of the elements?

Science.gov (United States)

Demming, Anna

2010-07-01

Throughout the history of science, carbon-based research has played a defining role in the development of a range of fundamental and technological fields. It was used in Avagadro's definition of the mole in the early 18th century, it provides the 'backbone' of molecules in organic compounds, and in the environmental debate currently raging in the press and international government discussions, the 'carbon footprint' has become the metric of our species' impact on our planet. Also in nanotechnology, with the discovery of various wonder materials, carbon is once again asserting its claim as king of the elements. Until the 1980s the only known forms of carbon were diamond, graphite and amorphous carbon, as in soot or charcoal. In 1985 Robert Curl, Harold Kroto and Richard Smalley reported the existence of fullerenes, spherical structures comprising hexagonal carbon rings [1], work for which they won the Nobel Prize for Chemistry in 1996 [2]. The discovery of fullerenes was followed in 1991 by Sumio Ijima with the discovery of rolled graphite sheets, the carbon nanotube [3]. The discovery of these novel carbon nanostructures inspired researchers in a range of fields, largely as a result of the extraordinary capacity for investigations of these structures to reveal ever more intriguing properties. One of the fascinating properties attributed to carbon nanotubes is their phenomenal strength, with a Young's modulus of single walled carbon nanotubes approaching a terapascal [4]. Ingenious methods of harnessing this strength have since been developed, including bucky paper, a term used to refer to a mat of randomly self-entangled carbon nanotubes. Steven Crannford and Markus Buehler have recently reported a novel computational technique for probing the mechanical properties of these structures and show that the Young's modulus of bucky paper can be tuned by manipulation of the carbon nanotube type and density [5]. The electrical properties of carbon nanotubes, which depend

Weighing the Smallest Stars

Science.gov (United States)

2005-01-01

NACO SDI camera was able to distinguish it as a "redder" dot surrounded by the "bluer" light from AB Dor A. The orbit of AB Dor C around AB Dor A is shown as a yellow ellipse. It takes 11.75 years for the 93 Jupiter-mass companion to complete this orbit. Turning this camera towards AB Dor A in February 2004, they were able for the first time to image a companion so faint - 120 times fainter than its star - and so near its star. Says Markus Hartung (ESO), member of the team: "This world premiere was only possible because of the unique capabilities of the NACO SDI instrument on the VLT. In fact, the Hubble Space Telescope tried but failed to detect the companion, as it was too faint and too close to the glare of the primary star." The tiny distance between the star and the faint companion (0.156 arcsec) is the same as the width of a one Euro coin (2.3 cm) when seen 20 km away. The companion, called AB Dor C, was seen at a distance of 2.3 times the mean distance between the Earth and the Sun. It completes a cycle around its host star in 11.75 years on a rather eccentric orbit. Using the companion's exact location, along with the star's known 'wobble', the astronomers could then accurately determine the companion's mass. The object, more than 100 times fainter than its close primary star, has one tenth of the mass of its host star, i.e., it is 93 times more massive than Jupiter. It is thus slightly above the brown dwarf limit. Using NACO on the VLT, the astronomers further observed AB Dor C at near infrared wavelengths to measure its temperature and luminosity. "We were surprised to find that the companion was 400 degrees (Celsius) cooler and 2.5 times fainter than the most recent models predict for an object of this mass," Close said. "Theory predicts that this low-mass, cool object would be about 50 Jupiter masses. But theory is incorrect: this object is indeed between 88 to 98 Jupiter masses." These new findings therefore challenge current ideas about the brown dwarf

12th WINFOCUS world congress on ultrasound in emergency and critical care.

Science.gov (United States)

Acar, Yahya; Tezel, Onur; Salman, Necati; Cevik, Erdem; Algaba-Montes, Margarita; Oviedo-García, Alberto; Patricio-Bordomás, Mayra; Mahmoud, Mustafa Z; Sulieman, Abdelmoneim; Ali, Abbas; Mustafa, Alrayah; Abdelrahman, Ihab; Bahar, Mustafa; Ali, Osama; Lester Kirchner, H; Prosen, Gregor; Anzic, Ajda; Leeson, Paul; Bahreini, Maryam; Rasooli, Fatemeh; Hosseinnejad, Houman; Blecher, Gabriel; Meek, Robert; Egerton-Warburton, Diana; Ćuti, Edina Ćatić; Belina, Stanko; Vančina, Tihomir; Kovačević, Idriz; Rustemović, Nadan; Chang, Ikwan; Lee, Jin Hee; Kwak, Young Ho; Kim, Do Kyun; Cheng, Chi-Yung; Pan, Hsiu-Yung; Kung, Chia-Te; Ćurčić, Ela; Pritišanac, Ena; Planinc, Ivo; Medić, Marijana Grgić; Radonić, Radovan; Fasina, Abiola; Dean, Anthony J; Panebianco, Nova L; Henwood, Patricia S; Fochi, Oliviero; Favarato, Moreno; Bonanomi, Ezio; Tomić, Ivan; Ha, Youngrock; Toh, Hongchuen; Harmon, Elizabeth; Chan, Wilma; Baston, Cameron; Morrison, Gail; Shofer, Frances; Hua, Angela; Kim, Sharon; Tsung, James; Gunaydin, Isa; Kekec, Zeynep; Ay, Mehmet Oguzhan; Kim, Jinjoo; Kim, Jinhyun; Choi, Gyoosung; Shim, Dowon; Lee, Ji-Han; Ambrozic, Jana; Prokselj, Katja; Lucovnik, Miha; Simenc, Gabrijela Brzan; Mačiulienė, Asta; Maleckas, Almantas; Kriščiukaitis, Algimantas; Mačiulis, Vytautas; Macas, Andrius; Mohite, Sharad; Narancsik, Zoltan; Možina, Hugon; Nikolić, Sara; Hansel, Jan; Petrovčič, Rok; Mršić, Una; Orlob, Simon; Lerchbaumer, Markus; Schönegger, Niklas; Kaufmann, Reinhard; Pan, Chun-I; Wu, Chien-Hung; Pasquale, Sarah; Doniger, Stephanie J; Yellin, Sharon; Chiricolo, Gerardo; Potisek, Maja; Drnovšek, Borut; Leskovar, Boštjan; Robinson, Kristine; Kraft, Clara; Moser, Benjamin; Davis, Stephen; Layman, Shelley; Sayeed, Yusef; Minardi, Joseph; Pasic, Irmina Sefic; Dzananovic, Amra; Pasic, Anes; Zubovic, Sandra Vegar; Hauptman, Ana Godan; Brajkovic, Ana Vujaklija; Babel, Jaksa; Peklic, Marina; Radonic, Vedran; Bielen, Luka; Ming, Peh Wee; Yezid, Nur Hafiza; Mohammed, Fatahul Laham; Huda, Zainal Abidin; Ismail, Wan Nasarudin Wan; Isa, W Yus Haniff W; Fauzi, Hashairi; Seeva, Praveena; Mazlan, Mohd Zulfakar

2016-09-01

Jinjoo Kim, Jinhyun Kim, Gyoosung Choi, Dowon ShimA27 Usefulness of abdominal ultrasound for acute pyelonephritis diagnosis after kidney transplantationJi-Han LeeA28 Lung ultrasound for assessing fluid tolerance in severe preeclampsiaJana Ambrozic, Katja Prokselj, Miha LucovnikA29 Optic nerve sheath ultrasound in severe preeclampsiaGabrijela Brzan Simenc, Jana Ambrozic, Miha LucovnikA30 Focused echocardiography monitoring in the postoperative period for non-cardiac patientsAsta Mačiulienė, Almantas Maleckas, Algimantas Kriščiukaitis, Vytautas Mačiulis, Andrius MacasA31 POCUS-guided paediatric upper limb fracture reduction: algorithm, tricks, and tipsSharad MohiteA32 Point-of-care lung ultrasound: a good diagnostic tool for pneumonia in a septic patientZoltan Narancsik, Hugon MožinaA33 A case of undergraduate POCUS (r)evolutionSara Nikolić, Jan Hansel, Rok Petrovčič, Una Mršić, Gregor ProsenA34 The Graz Summer School for ultrasound: from first contact to bedside application: three-and-a-half-day undergraduate ultrasound training: résumé after two years of continuous developmentSimon Orlob, Markus Lerchbaumer, Niklas Schönegger, Reinhard KaufmannA35 Usefulness of point-of-care ultrasound in the emergency room in a patient with acute abdominal painAlberto Oviedo-García, Margarita Algaba-Montes, Mayra Patricio-BordomásA36 Use of bedside ultrasound in a critically ill patient. A case reportAlberto Oviedo-García, Margarita Algaba-Montes, Mayra Patricio-BordomásA37 Diagnostic yield of clinical echocardiography for the emergency physicianAlberto Oviedo-García, Margarita Algaba-Montes, Mayra Patricio-BordomásA38 Focused cardiac ultrasound in early diagnosis of type A aortic dissection with atypical presentationChun-I Pan, Hsiu-Yung Pan, Chien-Hung WuA39 Detection of imperforated hymen by point-of-care ultrasoundHsiu-yung Pan, Chia-Te KungA40 Developing a point-of-care ultrasound curriculum for pediatric nurse practitioners practicing in the pediatric emergency

FOREWORD: Tackling inverse problems in a Banach space environment: from theory to applications Tackling inverse problems in a Banach space environment: from theory to applications

Science.gov (United States)

Schuster, Thomas; Hofmann, Bernd; Kaltenbacher, Barbara

2012-10-01

of concrete instances with special properties. The aim of this special section is to provide a forum for highly topical ongoing work in the area of regularization in Banach spaces, its numerics and its applications. Indeed, we have been lucky enough to obtain a number of excellent papers both from colleagues who have previously been contributing to this topic and from researchers entering the field due to its relevance in practical inverse problems. We would like to thank all contributers for enabling us to present a high quality collection of papers on topics ranging from various aspects of regularization via efficient numerical solution to applications in PDE models. We give a brief overview of the contributions included in this issue (here ordered alphabetically by first author). In their paper, Iterative regularization with general penalty term—theory and application to L1 and TV regularization, Radu Bot and Torsten Hein provide an extension of the Landweber iteration for linear operator equations in Banach space to general operators in place of the inverse duality mapping, which corresponds to the use of general regularization functionals in variational regularization. The L∞ topology in data space corresponds to the frequently occuring situation of uniformly distributed data noise. A numerically efficient solution of the resulting Tikhonov regularization problem via a Moreau-Yosida appriximation and a semismooth Newton method, along with a δ-free regularization parameter choice rule, is the topic of the paper L∞ fitting for inverse problems with uniform noise by Christian Clason. Extension of convergence rates results from classical source conditions to their generalization via variational inequalities with a priori and a posteriori stopping rules is the main contribution of the paper Regularization of linear ill-posed problems by the augmented Lagrangian method and variational inequalities by Klaus Frick and Markus Grasmair, again in the context of some

Editorial: Pedagogical Media Ecologies

Directory of Open Access Journals (Sweden)

Dorothee M. Meister

2014-07-01

learning and media ecologies with the material, global and ecological challenges that have become a part of the anthropocene. They do so by examining the mediation of a physical, architectural environment, their own departmental environment at Simon Fraser University. De Castell, Droumeva and Jenson uncover a range of practical and theoretical challenges, and explore the implications for both body and mind. Markus Deimann takes the reader back into the history of continental educational theory, to Humboldt’s (and others‘ expansive understanding of Bildung, to suggest a conceptual ecology germane to the manifold possibilities that are now on offer through open education. Deimann sees the «open paradigm» as changing education utterly – and for the better. It will do so, Deimann predicts, by «unbundling» resource and service provision, and assessment and accreditation functions that have for too long been monopolized by the educational monoliths known as «universities». Theo Hug’s contribution, «Media Form School – A Plea for Expanded Action Orientations and Reflective Perspectives» similarly looks to the past to envision possibilities for the future. Hug’s concern is with the narrow confines in which media are conceptualized and operationalized in many K-12 educational ecologies, and in the corresponding policy and curricular documents that further constrain and direct this action. Hug suggests looking to the recent past, the 1970s and 1960s, in which alternatives were envisioned not only by figures like McLuhan and Illich, but also intimated in the works of Austrian poets and artists. Norm Friesen provides the third «rearview mirror» perspective in his examination of the lecture as a trans-medial pedagogical form. From the late medieval university through to today’s IGNITE and TED talks, the lecture has accommodated and reflected a wide range of media ecologies, technical conditions and epistemological patterns. New media technologies –from the

PREFACE: Liquid-solid interfaces: structure and dynamics from spectroscopy and simulations Liquid-solid interfaces: structure and dynamics from spectroscopy and simulations

Science.gov (United States)

Gaigeot, Marie-Pierre; Sulpizi, Marialore

2012-03-01

the experimental recorded signatures. 'More traditional' DFT static calculations can be applied to complex objects at interfaces, providing their vibrational spectra, and two papers in this special section illustrate such approaches. Ceccet et al extract first hyperpolarizability tensors from DFT calculations on aliphatic chains and simulate the related VSFG spectra. They also investigate the effect of different functionals on the final signatures. Liegeois et al investigate functionalized surfaces, mainly focusing on IR and Raman spectral features, and provide very precise vibrational assignments depending on chemisorption or physisorption of the adsorbed molecules. We are grateful to all the authors for their contributions to this special section and we hope that readers will enjoy this collection of papers and that they will find further motivation to investigate and understand the complex phenomena occurring at interfaces. Liquid-solid interfaces contents The interfacial structure of water/protonated α-Al2O3 (112¯0) as a function of pHJ Sung, Y R Shen and G A Waychunas Strain relief and disorder in commensurate water layers formed on Pd(111)F McBride, A Omer, C M Clay, L Cummings, G R Darling and A Hodgson H2O on Pt(111): structure and stability of the first wetting layer Sebastian Standop, Markus Morgenstern, Thomas Michely and Carsten Busse Effect of a thioalkane capping layer on the first hyperpolarizabilities of gold and silver nanoparticles Yara El Harfouch, Emmanuel Benichou, Franck Bertorelle, Isabelle Russier-Antoine, Christian Jonin, Noelle Lascoux and Pierre F Brevet Predicting the acidity constant of a goethite hydroxyl group from first principlesKevin Leung and Louise J Criscenti Oxide/water interfaces: how the surface chemistry modifies interfacial water properties Marie-Pierre Gaigeot, Michiel Sprik and Marialore Sulpizi Vibrational spectrum at a water surface: a hybrid quantum mechanics/molecular mechanics molecular dynamics approach Tatsuya

EDITORIAL: Focus on Attosecond Physics

Science.gov (United States)

Bandrauk, André D.; Krausz, Ferenc; Starace, Anthony F.

2008-02-01

Chelkowski and A D Bandrauk Broadband generation in a Raman crystal driven by a pair of time-delayed linearly chirped pulses Miaochan Zhi and Alexei V Sokolov Ultrafast nanoplasmonics under coherent control Mark I Stockman Attosecond pulse carrier-envelope phase effects on ionized electron momentum and energy distributions: roles of frequency, intensity and an additional IR pulse Liang-You Peng, Evgeny A Pronin and Anthony F Starace Angular encoding in attosecond recollision Markus Kitzler, Xinhua Xie, Stefan Roither, Armin Scrinzi and Andrius Baltuska Polarization-resolved pump-probe spectroscopy with high harmonics Y Mairesse, S Haessler, B Fabre, J Higuet, W Boutu, P Breger, E Constant, D Descamps, E Mével, S Petit and P Salières Macroscopic effects in attosecond pulse generation T Ruchon, C P Hauri, K Varjú, E Mansten, M Swoboda, R López-Martens and A L'Huillier Monitoring long-term evolution of molecular vibrational wave packet using high-order harmonic generation M Yu Emelin, M Yu Ryabikin and A M Sergeev Intense single attosecond pulses from surface harmonics using the polarization gating technique S G Rykovanov, M Geissler, J Meyer-ter-Vehn and G D Tsakiris Imaging of carrier-envelope phase effects in above-threshold ionization with intense few-cycle laser fields M F Kling, J Rauschenberger, A J Verhoef, E Hasović, T Uphues, D B Milošević, H G Muller and M J J Vrakking Self-compression of optical laser pulses by filamentation A Mysyrowicz, A Couairon and U Keller Towards efficient generation of attosecond pulses from overdense plasma targets N M Naumova, C P Hauri, J A Nees, I V Sokolov, R Lopez-Martens and G A Mourou Quantum-path control in high-order harmonic generation at high photon energies Xiaoshi Zhang, Amy L Lytle, Oren Cohen, Margaret M Murnane and Henry C Kapteyn Time-resolved mapping of correlated electron emission from helium atom in an intense laser pulse C Ruiz and A Becker Pump and probe ultrafast electron dynamics in LiH: a computational study

FOREWORD: The 70th birthday of Professor Stig Stenholm The 70th birthday of Professor Stig Stenholm

Science.gov (United States)

Suominen, Kalle-Antti

2010-09-01

information [7] and in Stockholm he had, again, very successful postdocs such as Ulf Leonhardt. Finally, in 2005, Stig Stenholm retired, although he is still active, writing papers, taking part in conferences and making research visits. We honoured his 70th birthday at the CEWQO2009 conference, and hope that the future provides us with further opportunities for such events. Looking at the obituary of Dirk ter Haar, I see that his style with students reminds me of Stig's approach. In my opinion, Stig expects independence and initiative from a student, giving perhaps a broad topic in which the student is expected to find his or her own way, whilst working perhaps with a postdoc. Juha Javanainen has talked about the 'sink or swim' style (not referring to Stig, though). There is a famous series of children's books about Moomin trolls by Tove Jansson (another Swedish-speaking Finn like Stig). In one of them, the Moomin find in early spring a small flower in a patch of land uncovered by snow, pushing its way up. One of them wants to cover it against frost during the night, but another says 'Don't, it'll fare better later if it has some difficulties at first'. At CEWQO2009 Stig gave the full list of his finished PhD students: Rainer Salomaa (1973), Temba Dlodlo (1980), Juha Javanainen (1980), Markus Lindberg (1985), Matti Kaivola (1985), Birger Ståhlberg (1985), Kalle-Antti Suominen (1992), Mackillo Kira (1995), Päivi Törmä (1996), Asta Paloviita (1997), Patrik Öhberg (1998), Martti Havukainen (1999), Erika Andersson (2000), Pawel Piwnicki (2001), Åsa Larson (2001), Markku Jääskeläinen (2003), and Jonas Larson (2005). One should also mention Erkki Kyrölä, who eventually graduated at Rochester and Olli Serimaa, who never graduated but published some important early-stage laser cooling work. As a final note I must mention a passion that Stig and I share, namely books. I have nearly 400 professional physics and mathematics books, but I am certain that the size of Stig

6th International Symposium on Molecular Allergology (ISMA

Directory of Open Access Journals (Sweden)

Christiane Hilger

2016-10-01

Full Text Available Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE-antibodies to alpha-Gal Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert O2 Structure solution of Pla l 1 suggests similar folding of Ole e 1-like family members but distinct immunological properties Sabrina Wildner, Teresa Stemeseder, Regina Freier, Peter Briza, Roland Lang, Eva Batanero, Mayte Villalba, Jonas Lidholm, Thomas Hawranek, Fatima Ferreira, Hans Brandstetter, Gabriele Gadermaier Symposium 2: New allergen molecules in the spotlight O3 Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed (Ambrosia artemisiifolia Philippe Moingeon, Rachel Groeme, Julien Bouley, Véronique Bordas, Maxime Le Mignon, Laetitia Bussières, Aurélie Lautrette, Laurent Mascarell, Vincent Lombardi, Véronique Baron-Bodo, Henri Chabre, Thierry Batard, Emmanuel Nony O4 Production and characterization of polybia paulista recombinant antigen 5: a valuable diagnostic tool Karine Marafigo De Amicis, Alexandra Sayuri Watanabe, Daniele Danella Figo, José Roberto Aparecido Dos Santos-Pinto, Mario Sergio Palma, Fabio Fernandes Morato Castro, Jorge Kalil, Therese Wohlschlager, Peter Briza, Sabrina Wildner, Fatima Ferreira-Briza, Gabriele Gadermaier, Keity Souza Santos Symposium 3: Progress in molecular and cellular diagnosis O5 Basophil activation test with recombinant Pru p 3; identifying genuine peach allergic patients Margaretha Faber, Athina Van Gasse, Vito Sabato, Margo M. Hagendorens, Chris H. Bridts, Luc S. De Clerck, Araceli Diaz Perales, Didier Ebo O6 Nanofluidic technology enables rapid, near

Proceedings of the International Cancer Imaging Society (ICIS 16th Annual Teaching Course

Directory of Open Access Journals (Sweden)

Dow-Mu Koh

2016-10-01

Full Text Available Table of contents O1 Tumour heterogeneity: what does it mean? Dow-Mu Koh O2 Skeletal sequelae in adult survivors of childhood cancer Sue Creviston Kaste O3 Locoregional effects of breast cancer treatment Sarah J Vinnicombe O4 Imaging of cancer therapy-induced CNS toxicity Giovanni Morana, Andrea Rossi O5 Screening for lung cancer Christian J. Herold O6Risk stratification of lung nodules Theresa C. McLoud O7 PET imaging of pulmonary nodules Kirk A Frey O8 Transarterial tumour therapy Bernhard Gebauer O9 Interventional radiology in paediatric oncology Derek Roebuck O10 Image guided prostate interventions Jurgen J. Fütterer O11 Imaging cancer predisposition syndromes Alexander J. Towbin O12Chest and chest wall masses Thierry AG Huisman O13 Abdominal masses: good or bad? Anne MJB Smets O14 Hepatobiliary MR contrast: enhanced liver MRI for HCC diagnosis and management Giovanni Morana O15 Role of US elastography and multimodality fusion for managing patients with chronic liver disease and HCC Jeong Min Lee O16 Opportunities and challenges in imaging metastatic disease Hersh Chandarana O17 Diagnosis, treatment monitoring, and follow-up of lymphoma Marius E. Mayerhoefer, Markus Raderer, Alexander Haug O18 Managing high-risk and advanced prostate cancer Matthias Eiber O19 Immunotherapy: imaging challenges Bernhard Gebauer O20 RECIST and RECIST 1.1 Andrea Rockall O21 Challenges of RECIST in oncology imaging basics for the trainee and novice Aslam Sohaib O22 Lymphoma: PET for interim and end of treatment response assessment: a users’ guide to the Deauville Score Victoria S Warbey O23 Available resources Hebert Alberto Vargas O24 ICIS e-portal and the online learning community Dow-Mu Koh O25 Benign lesions that mimic pancreatic cancer Jay P Heiken O26 Staging and reporting pancreatic malignancies Isaac R Francis, Mahmoud, M Al-Hawary, Ravi K Kaza O27 Intraductal papillary mucinous neoplasm Giovanni Morana O28 Cystic pancreatic tumours Mirko D’Onofrio O

Electron-Exchange Reactions of Aromatic Molecules; Echanges d'Electrons de Molecules Aromatiques; Reaktsii ehlektronnogo obmena aromaticheskikh molekul; Reacciones de Intercambio Electronico en Moleculas Aromaticas

Energy Technology Data Exchange (ETDEWEB)

Malachesky, P. A.; Miller, T. A.; Layloff, T.; Adams, R. N. [University of Kansas, Lawrence, KS (United States)

1965-10-15

'shoe kolichestvo informacii otnositel'no skorosti mehanizma processov neorganicheskogo obmena jelektronov. V protivopolozhnost' jetomu chisto organicheskim sistemam udeljalos' dovol'no neznachitel'noe vnimanie. Skorost' gomogennogo jelektronnogo obmena (k{sub 0bm})i geterogennye konstanty skorosti dlja jelektrodnoj reakcii (k{sub jel}) byli izmereny lish' dlja neskol'kih ugle- vodorodov . Bylo izmereno k{sub 0bm} dlja razlichnyh aromaticheskih sistem, v tom chisle uglevodorodov, hinonov i nitrosoedinenij. Jeti izmerenija byli provedeny posredstvom jelektronnogo para- magnitnogo rezonansa (EPR) s perenosom izmerenij na smesi radikal'nyh ionov i ih mate- rinskih soedinenij. Nam takzhe udalos' izmerit' k0bm s takoj tochnost'ju, kotoraja pozvo- ljaet obnaruzhit' nebol'shie razlichija, vyzvannye, verojatno; molekuljarnoj strukturoj i sre- doj. Uglevodorodnye sistemy, podobnye antracenovomu/antracenovomu anionu, javljajutsja ves'ma bystrymi pri velichine k{sub 0gM} priblizitel'no 10{sup 8}-10{sup 9} litr mol{sup -i} sek{sup -1}. Nekotorye zame- shhennye aromaticheskie soedinenija, podobnye hinonam i nitrilam, takzhe javljajutsja ves'ma bystrymi. Odnako, kogda imeetsja sil'naja funkcija jelektronnogo akceptora, podobno nitro- gruppe v nitrobenzole, velichina k{sub 0gM} sokrashhaetsja na faktor 10. Predstavljaetsja vozmozhnym korrelirovat' izmenenija v k{sub obm} v serijah nitrobenzola s pomoshh'ju plotnosti neparnyh jelek- tronov po konstantam svjazi N{sup 14} spektra EPR. Krome togo, nitroaromaticheskie serii obna- ruzhivajut ochen' bol'shie razlichija v znachenijah k{sub 0b} m s rastvorjajushhej sistemoj. Jeti izmene- nija mozhno korrelirovat' blagodarja nedavnim issledovanijam jeffekta sol'vatacii na sverh- tonkie konstanty svjazi. V poslednee vremja Markus rassmotrel teoriju himicheskogo i jelektrohimicheskogo pere- nosa jelektronov i predlozhil korreljacii mezhdu znachenijami k{sub obm} i k{sub jel}. Nami special'no byl izmeren kjel dlja sistemy nitrobenzola v uslovijah, kotorye

Discovery of a Circumstellar Disk in the Lagoon Nebula

Science.gov (United States)

1997-04-01

velocities of the interacting matter. The astronomer team therefore intends to carry out further adaptive-optics imaging and spectroscopy with the ESO instruments later this year. Great prospects for related research projects The detection of this new object shows that direct proofs for the existence of circumstellar disks in distant star-forming regions are possible with currently available telescopes. It also represents an important step forward for the preparation of scientific programmes devoted to the formation of stars and planets that will soon be carried out with the ESO Very Large Telescope (VLT). The new results demonstrate that the high-resolution images that will be obtained with the future giant telescopes and, especially, with the VLT Interferometer (VLTI) will most likely lead to important breakthroughs in our understanding on the complicated processes of star formation. This will in turn cast new light on how the Sun and the Earth came into existence, more than 4.5 billion years ago. Where to find additional information More details on the investigation of star formation in M8 and the newly discovered proplyd can be found on the World-Wide Web page of the Thüringer Landessternwarte (URL: http://www.tls-tautenburg.de/M8.html Notes: [1] The team consists of Bringfried Stecklum and Steffen Richter (Thüringer Landessternwarte, Tautenburg, Germany), Thomas Henning, Ralf Launhardt and Markus Feldt (Astrophysikalisches Institut und Universitätssternwarte, Friedrich-Schiller-Universität Jena), Thomas L. Hayward (Center for Radiophysics & Space Research, Cornell University, New York, USA), Melvin G. Hoare (Physics & Astronomy Department, Leeds University, UK) and Peter Hofner (National Astronomy & Ionosphere Center, Arecibo, USA). [2] Some years ago, infrared observations with the IRAS spacecraft led to the discovery of a disk around the isolated, nearby southern star Beta Pictoris . [3] This result was published in a paper by Stecklum et al. in 1995 (ApJ 445, L

SINFONI Opens with Upbeat Chords

Science.gov (United States)

2004-08-01

the massive black hole at the Galactic Centre, with crucial information on the nature of the individual stars and their motions (Appendix C), * images and spectra of the heavily dust-obscured, active centre of the Circinus galaxy, one of the closest active galaxies, showing ordered rotation in this area and distinct broad and narrow components of the spectral line of Ca7+-ions (Appendix D), * images and spectra of the less obscured central area of NGC 7469, a more distant active galaxy, with spectral lines of molecular hydrogen and carbon monoxide showing a very different distribution of these species (Appendix E), * images and spectra of the Infrared Luminous Galaxy (ULIRG) NGC 6240, a typical galaxy merger, displaying important differences between the two nuclei (Appendix F), and * images and spectra of the young starforming galaxies BX 404/405, casting more light on the formation of disks in spiral galaxies (Appendix G) The SINFONI Teams ESO PR Photo 24g/04 ESO PR Photo 24g/04 Members of the SINFONI Adaptive Optics Commissioning Team [Preview - JPEG: 646 x 400 pix - 198k] [Normal - JPEG: 1291 x 800 pix - 618k] ESO PR Photo 24h/04 ESO PR Photo 24h/04 Members of the SPIFFI Commissioning Team [Preview - JPEG: 491 x 400 pix - 193k] [Normal - JPEG: 982 x 800 pix - 482k] Captions: ESO PR Photo 24g/04 Members of the SINFONI Adaptice Optics Commissioning Team in the VLT Control Room in the night between June 7 - 8, 2004. From left to right and top to bottom: Thomas Szeifert, Sebastien Tordo, Stefan Stroebele, Jerome Paufique, Chris Lidman, Robert Donaldson, Enrico Fedrigo, Markus Kissler Patig, Norbert Hubin, Henri Bonnet. ESO PR Photo 24h/04: Members of the SPIFFI Commissioning Team on August 17. From left to right, Roberto Abuter, Frank Eisenhauer, Andrea Gilbert and Matthew Horrobin. The first SINFONI results have been greeted with enthusiasm, in particular by the team of astronomers and engineers from the consortium of German and Dutch institutes and ESO who worked on