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Sample records for marked structural differences

  1. Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors

    Energy Technology Data Exchange (ETDEWEB)

    Katz, Jason D.; Haidle, Andrew; Childers, Kaleen K.; Zabierek, Anna A.; Jewell, James P.; Hou, Yongquan; Altman, Michael D.; Szewczak, Alexander; Chen, Dapeng; Harsch, Andreas; Hayashi, Mansuo; Warren, Lee; Hutton, Michael; Nuthall, Hugh; Su, Hua-Poo; Munshi, Sanjeev; Stanton, Matt G.; Davies, Ian W.; Munoz, Ben; Northrup, Alan (Merck)

    2017-01-01

    The initial structure activity relationships around an isoindoline uHTS hit will be described. Information gleaned from ligand co-crystal structures allowed for rapid refinements in both MARK potency and kinase selectivity. These efforts allowed for the identification of a compound with properties suitable for use as an in vitro tool compound for validation studies on MARK as a viable target for Alzheimer’s disease.

  2. Male and female meadow voles Microtus pennsylvanicus respond differently to scent marks from the top- middle-, and bottom-scent donors of an over-mark

    Directory of Open Access Journals (Sweden)

    Michael H. FERKIN, Nicholas J. HOBBS, Benjamin D. FERKIN, Adam C.FERKIN, Daniel A. FERKIN

    2011-08-01

    Full Text Available Previous studies have shown that individuals responded preferentially to the mark of the top-scent donor relative to that of the bottom-scent donor of an over-mark. However, terrestrial mammals are likely to encounter over-marks consisting of the scent marks of more than two same-sex conspecifics in the intersections of runways, near the nests of sexually receptive female conspecifics, and inside and along the borders of the territories of conspecifics. We determined how meadow voles, Microtus pennsylvanicus, respond to the marks of the top-, middle-, and bottom-scent donors of an over-mark. We tested the hypothesis that voles exposed to an over-mark will respond preferentially to the scent marks that were deposited more recently, the scent marks that were on top or near the top of the over-mark, compared to the scent marks that were deposited earlier or near the bottom of the over-mark. Voles spent more time investigating the mark of the top-scent donor than that of the either the middle- or bottom-scent donor. However, males but not female voles spent more time investigating the middle-scent mark than the bottom-scent mark. We also tested the hypothesis that voles evaluate and respond to over-marks differently from single scent marks. Voles spent more time investigating the marks of the top-, middle-, and bottom-scent donors compared to scent marks that were not part of the over-mark. Voles can distinguish among the overlapping scent marks of three scent donors and sex differences exist in the values they appear to attach to each of these scent marks [Current Zoology 57 (4: 441–448, 2011].

  3. Evaluation of different marking methods for spiny-cheek crayfish (Orconectes limosus

    Directory of Open Access Journals (Sweden)

    Buřič M.

    2008-10-01

    Full Text Available Different methods of marking were evaluated for Orconectes limosus (CL = carapace length, 12–37 mm under laboratory conditions: the use of passive integrated transponders, visible implant elastomers, visible implant alphanumeric tags, and cauterization. High survival (> 90% was obtained with all methods tested. Tag retention and readability were evaluated immediately after marking, before and after ecdysis, with moult increments and number of moults been recorded. Marking using cauterization negatively affects the percent moult increment (PMI of crayfish. The average PMI of 15 ± 0.88% did not differ between males (15 ± 1.41 mm and females (15 ± 1.12 mm. It was found that PMI gradually decreased with an increase in CL. Sixty-one moults were observed, with 12 crayfish (6 juveniles and 6 adults presenting two moults. Time between moults varied from 3 to 7 weeks. CL was increased with over 28 ± 2.68% due to two moults. Three females moulted twice after successful hatching and carrying of juveniles.

  4. Eelgrass (Zostera marina) food web structure in different environmental settings

    DEFF Research Database (Denmark)

    Thormar, Jonas Gjaldbæk; Hasler-Sheetal, Harald; Baden, Susanne

    2016-01-01

    his study compares the structure of eelgrass (Zostera marina L.) meadows and associated food webs in two eelgrass habitats in Denmark, differing in exposure, connection to the open sea, nutrient enrichment and water transparency. Meadow structure strongly reflected the environmental conditions...... composition and food web structure also differed markedly between sites with the eutrophicated, enclosed site having higher biomass of consumers and less complex food web. These relationships resulted in a column shaped biomass distribution of the consumers at the eutrophicated site whereas the less nutrient...

  5. Marking for Structure using Boolean Feedback | Louw | Journal for ...

    African Journals Online (AJOL)

    This paper presents evidence that marking student texts with well considered checklists is more effective than marking by hand. An experiment conducted on first-year students illustrated that the checklists developed to mark introductions, conclusions and paragraphs yielded better revision results than handwritten ...

  6. Responses of female rock lizards to multiple scent marks of males: effects of male age, male density and scent over-marking.

    Science.gov (United States)

    Martín, José; López, Pilar

    2013-03-01

    Scent-marked substrates may inform conspecifics on the characteristics of territorial males. Scent-marks of male Carpetan rock lizards (Iberolacerta cyreni) affect space use of females, which by selecting an area may increase the probability of mating with the male that has scent-marked that area. However, males do not hold exclusive territories, and scent-marks of different individual males are often together. This may provide complex information from multiple sources on the social structure. Here, we examined female preference in response to scent marks of various males and combinations in a laboratory experiment. Females preferred areas scent-marked by territorial old males against those scent-marked by young satellite-sneaker males. This reflected the known preference of females for mating with old males. In a second experiment, females preferred areas scent-marked by two males to areas of similar size marked by a single male. This may increase the probability of obtaining multiple copulations with different males, which may favour sperm competition and cryptic female choice, or may be a way to avoid infertile males. Finally, when we experimentally over-marked the scent-marks of an old male with scent-marks of a young male, females did not avoid, nor prefer, the over-marked area, suggesting that the quality of the old male may override the presence of a satellite male. We suggest that, irrespective of the causes underlying why a female selects a scent-marked area, this strategy may affect her reproductive success, which may have the same evolutionary consequences that "direct" mate choice decisions of other animals. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Linguistic gender marking and its international business ramifications

    OpenAIRE

    Estefania Santacreu-Vasut; Oded Shenkar; Amir Shoham

    2014-01-01

    We analyze the impact of language-based gender distinctions within languages’ grammatical structures on women’s corporate presence. Using four different data sets, we find that countries where the dominant language marks gender more intensely have significantly lower female participation on boards of directors and in senior management, as well as smaller female-led corporate teams. We also find that the gender marking of the language used in the headquarters’ home country impacts female prese...

  8. Radio opaque marking of pelvic structures : an adjunct to primary radiation therapy of carcinoma of the uterine cervix

    International Nuclear Information System (INIS)

    Nori, Dattatreyudu; Noumoff, Joel; Cassir, Jorge; Hilaris, B.S.; Lewis, J.L.

    1980-01-01

    A standardized method of clipping pelvic structures at the time of pretreatment laparotomy for cervical carcinoma is presented. The accurate localization of pelvic structures by clip markers greatly enhances the precision of computerized dosimetry in administering intracavitary radiation. The technical details of the marking procedures, its usefulness and some examples reviewing the advantage of clipping are elaborated. Radio-opaque marking with special reference to computerized dosimetry is also given. (author)

  9. Mark retention of calcein in Cisco and Bloater

    Science.gov (United States)

    Chalupnicki, Marc A.; Mackey, Gregg; Nash, Kendra; Chiavelli, Richard; Johnson, James H.; Kehler, Thomas; Ringler, Neil H.

    2016-01-01

    Since 2012, a multi-agency initiative to restore these native forage species has been under way. Evaluating the restoration success of Cisco Coregonus artedi and Bloater C. hoyi in Lake Ontario waters requires methods to identify stocked fish. However, juvenile Cisco and Bloater are fragile; thus, mass marking techniques that reduce the handling of individual fish are required and have not previously been evaluated. In 2014–2015 we evaluated the usefulness of calcein (SE-MARK) as a marker on bony structures, including the otolith. Juvenile Bloater and Cisco (14, 100, 128 d old) were immersed in a calcein bath at 5,000 mg/L of water for 4 min to apply the chemical marker. Observations of the marking retention were evaluated 8 d following the treatment. All fish immersed in calcein had strong brilliant marks (rating scale 3) on all bony structures including scales, fin rays, jaw bones, and vertebrate. The otolith was the only hard structure that did not show a brilliant marking due to the opaque nature of the structure. Our results suggest that calcein produces a strong discernable mark on hard bony structures of Cisco and Bloater; however, long-term retention needs further study.

  10. De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture.

    Science.gov (United States)

    Di Pierro, Michele; Cheng, Ryan R; Lieberman Aiden, Erez; Wolynes, Peter G; Onuchic, José N

    2017-11-14

    Inside the cell nucleus, genomes fold into organized structures that are characteristic of cell type. Here, we show that this chromatin architecture can be predicted de novo using epigenetic data derived from chromatin immunoprecipitation-sequencing (ChIP-Seq). We exploit the idea that chromosomes encode a 1D sequence of chromatin structural types. Interactions between these chromatin types determine the 3D structural ensemble of chromosomes through a process similar to phase separation. First, a neural network is used to infer the relation between the epigenetic marks present at a locus, as assayed by ChIP-Seq, and the genomic compartment in which those loci reside, as measured by DNA-DNA proximity ligation (Hi-C). Next, types inferred from this neural network are used as an input to an energy landscape model for chromatin organization [Minimal Chromatin Model (MiChroM)] to generate an ensemble of 3D chromosome conformations at a resolution of 50 kilobases (kb). After training the model, dubbed Maximum Entropy Genomic Annotation from Biomarkers Associated to Structural Ensembles (MEGABASE), on odd-numbered chromosomes, we predict the sequences of chromatin types and the subsequent 3D conformational ensembles for the even chromosomes. We validate these structural ensembles by using ChIP-Seq tracks alone to predict Hi-C maps, as well as distances measured using 3D fluorescence in situ hybridization (FISH) experiments. Both sets of experiments support the hypothesis of phase separation being the driving process behind compartmentalization. These findings strongly suggest that epigenetic marking patterns encode sufficient information to determine the global architecture of chromosomes and that de novo structure prediction for whole genomes may be increasingly possible. Copyright © 2017 the Author(s). Published by PNAS.

  11. Ultrafast lasers for precise and corrosion free marking on chirurgical steels

    Science.gov (United States)

    Neugebauer, Christoph; Aalderink, Dennis; Maurer, Erich; Faisst, Birgit; Budnicki, Aleksander

    2017-02-01

    The unique properties of ultrashort laser pulses and the decrease of invest pave the way to numerous novel applications. Even in the very price sensitive field of laser marking, ultrashort laser can compete due to a new cost structure and remarkable properties of the marking results. In this study we concentrated on industrial marking of medical equipment by using IR ultrashort lasers and compared the results with common marking laser systems. We demonstrate the benefits of ultrashort lasers marking on chirurgical devices, observing the influence of pulse energy, pulse duration, scanning velocity in respect to the visibility, corrosion resistance and long term durability under clinical conditions. Nowadays many parts and products are marked for the purpose of identification and traceability. One kind of laser marking is the well known annealing of stainless steel by nanosecond marking lasers. When annealing occurs a colored oxide layer grows due to the local heating of the material surface. Compared to the raw material, the annealed marking shows increased corrosion sensitivity. Regarding the traceability, the poor durability of the ns marking resulting in contrast reduction and the corrosion susceptibility are a huge problem. Therefore three different laser sources with ns-psfs pulse duration were observed. The focus rests on the realization of parameter studies (various lasers) and their effect on the corrosion and passivation behavior. Furthermore analysis of the oxide layers by use of EDX and XRD were performed to obtain further information on the composition and structure of the markings.

  12. Evaluation of marking efficiency of different alizarin red S concentrations on body fish structures in Oreochromis niloticus (Perciformes: Cichlidae juveniles

    Directory of Open Access Journals (Sweden)

    Ana L. Ibáñez

    2013-03-01

    Full Text Available The use of alizarin red S (ARS marked tilapias could provide valuable fisheries management information to evaluate fish stocking events and may facilitate aquaculture management practices. As a new technique in fishes, the aim of this study was to compare and evaluate the chemical marks produced in tilapia juveniles by ARS through two treatments: 1 12 hours of immersion and 2 immersion after osmotic induction. This was analyzed at three concentrations: 50, 75 and 100mg/l, and in three structures: otoliths, fish scales and caudal fin rays of Oreochromis niloticus juveniles. After three culture months 80% of specimens were analyzed and significant differences (pEl uso de alizarina roja S (ARS para marcar tilapias podría proporcionar información valiosa para el manejo de su pesquería. Para evaluar pesquerías acuaculturales manejadas con siembras o repoblamientos de peces se comparó y evaluó la marca producida por la alizarina roja S, empleando dos tratamientos: 1 Inmersión en ARS durante 12h; e 2 Inmersión en ARS después de un choque osmótico. El análisis se realizó a tres concentraciones: 50, 75 y 100mg/l y en tres estructuras: otolitos, escamas y radios de la aleta caudal de Oreochromis niloticus. Ochenta por ciento de los ejemplares fueron cultivados durante tres meses y analizados posteriormente. Los resultados mostraron diferencias entre las concentraciones de la marca para el tratamiento de 12h de inmersión mientras que no hubo diferencias entre las concentraciones para el tratamiento con inducción osmótica. Se encontraron diferencias en la intensidad de la marca entre los tratamientos para otolitos y radios de las aletas pero para las escamas no hubo diferencias significativas. Todas las concentraciones produjeron marcas (desde débiles a intensas, sin embargo la concentración de 100mg/l no produjo marcas débiles. El tratamiento por inducción osmótica presentó mayores niveles de mortalidad. Después de ocho meses de

  13. A large-scale examination of the effectiveness of anonymous marking in reducing group performance differences in higher education assessment.

    Directory of Open Access Journals (Sweden)

    Daniel P Hinton

    Full Text Available The present research aims to more fully explore the issues of performance differences in higher education assessment, particularly in the context of a common measure taken to address them. The rationale for the study is that, while performance differences in written examinations are relatively well researched, few studies have examined the efficacy of anonymous marking in reducing these performance differences, particularly in modern student populations. By examining a large archive (N = 30674 of assessment data spanning a twelve-year period, the relationship between assessment marks and factors such as ethnic group, gender and socio-environmental background was investigated. In particular, analysis focused on the impact that the implementation of anonymous marking for assessment of written examinations and coursework has had on the magnitude of mean score differences between demographic groups of students. While group differences were found to be pervasive in higher education assessment, these differences were observed to be relatively small in practical terms. Further, it appears that the introduction of anonymous marking has had a negligible effect in reducing them. The implications of these results are discussed, focusing on two issues, firstly a defence of examinations as a fair and legitimate form of assessment in Higher Education, and, secondly, a call for the re-examination of the efficacy of anonymous marking in reducing group performance differences.

  14. A large-scale examination of the effectiveness of anonymous marking in reducing group performance differences in higher education assessment.

    Science.gov (United States)

    Hinton, Daniel P; Higson, Helen

    2017-01-01

    The present research aims to more fully explore the issues of performance differences in higher education assessment, particularly in the context of a common measure taken to address them. The rationale for the study is that, while performance differences in written examinations are relatively well researched, few studies have examined the efficacy of anonymous marking in reducing these performance differences, particularly in modern student populations. By examining a large archive (N = 30674) of assessment data spanning a twelve-year period, the relationship between assessment marks and factors such as ethnic group, gender and socio-environmental background was investigated. In particular, analysis focused on the impact that the implementation of anonymous marking for assessment of written examinations and coursework has had on the magnitude of mean score differences between demographic groups of students. While group differences were found to be pervasive in higher education assessment, these differences were observed to be relatively small in practical terms. Further, it appears that the introduction of anonymous marking has had a negligible effect in reducing them. The implications of these results are discussed, focusing on two issues, firstly a defence of examinations as a fair and legitimate form of assessment in Higher Education, and, secondly, a call for the re-examination of the efficacy of anonymous marking in reducing group performance differences.

  15. Morphological structure mediates the notional meaning of gender marking: Evidence from the gender-congruency effect in Hebrew speech production.

    Science.gov (United States)

    Deutsch, Avital; Dank, Maya

    2018-02-01

    This study investigated the gender-congruency effect of animate nouns in Hebrew. The Picture-Word Interference paradigm was used to manipulate gender congruency between target pictures and spoken distractors. Naming latency revealed an inhibitory gender-congruency effect, as naming the pictures took longer in the presence of a gender-congruent distractor than with a distractor from a different gender category. The inhibitory effect was demonstrated for feminine (morphologically marked) nouns, across two stimulus-onset asynchronies (SOAs) (Experiments 1a and 1b), and masculine (morphologically unmarked) nouns (Experiment 2). The same pattern was observed when participants had to produce bare nouns (Experiment 1) or gender-marked noun phrases (Experiment 3). The inhibitory pattern of the effect resembles previous findings of bare nouns in a subset of Romance languages, including Italian and Spanish. These findings add to previous research which investigated the gender-congruency effect of inanimate nouns, where no effect of gender-congruent words was found. The results are discussed in relation to the null effect previously found for inanimate nouns. The comparison of the present and previous studies is motivated by a common linguistic distinction between animate and inanimate nouns in Hebrew, which ascribes grammatical gender specifications to derivational structures (for inanimate nouns) versus inflectional structures (for animate nouns). Given the difference in the notional meaning of gender specification for animate and inanimate nouns, the case of Hebrew exemplifies how language-specific characteristics, such as rich morphological structures, can be used by the linguistic system to express conceptual distinctions at the form-word level.

  16. Augmented marked graphs

    CERN Document Server

    Cheung, King Sing

    2014-01-01

    Petri nets are a formal and theoretically rich model for the modelling and analysis of systems. A subclass of Petri nets, augmented marked graphs possess a structure that is especially desirable for the modelling and analysis of systems with concurrent processes and shared resources.This monograph consists of three parts: Part I provides the conceptual background for readers who have no prior knowledge on Petri nets; Part II elaborates the theory of augmented marked graphs; finally, Part III discusses the application to system integration. The book is suitable as a first self-contained volume

  17. Do olfactory behaviour and marking responses of Konik polski stallions to faeces from conspecifics of either sex differ?

    Science.gov (United States)

    Jezierski, Tadeusz; Jaworski, Zbigniew; Sobczyńska, Magdalena; Ensminger, John; Górecka-Bruzda, Aleksandra

    2017-09-27

    The aim of the study was to assess whether adult stallions differentiate their olfactory and marking behaviour towards the excreta of their potential male rivals and mares. Four Konik polski stallions were individually exposed simultaneously to their own and each others' faeces as well as faeces of mares in oestrus vs. dioestrus. Five series of 30min observation sessions were conducted in a round pen each on two consecutive days from March to July, totaling in 5h observation per stallion. Stallions sniffed and displayed flehmen reaction towards mares' faeces significantly longer (P<0.01) than towards stallions' faeces. No significant differences were found in marking by defecations upon stallions' vs. mares' faeces. The stallions urinated exclusively on mares' faeces. Sniffing, flehmen, defecations and urinations performed towards faeces of mares in oestrus vs. dioestrus did not differ significantly. The results showed that stallions differentiate their olfactory behaviour towards excreta of conspecifics of different sex but perhaps not towards faeces of females in different reproductive status. This for the first time establishes that stallions exhibit different marking behaviour upon stallions' vs. mares' faeces. It is hypothesized that marking of other stallions' faeces by defecation may advertise presence of the stallion, whereas marking of mares' faeces by urination may serve to mask the presence of a mare to prevent potential rivals from locating the mare in an area where mares' faeces are found. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Analysis of a Mark II containment structure for hydrodynamic loads in suppression pool

    International Nuclear Information System (INIS)

    Bedrosian, B.

    1978-01-01

    During pressure-relief modes of BWR plant operation forcing signals are introduced into the suppression pool at discrete locations: exit nozzles of SRV discharge pipes (quenchers or ramsheads). These forcing signals are transmitted through the water of the suppression pool and, after reaching the pool boundaries, act as loadings on the containment structure wetted perimeter. The response of the containment structure is influenced by the presence of water as it interacts with the structure during application of the load. An adequate analysis must account for fluid-structure interaction (FSI) effects. This paper presents an exact formulation for solving the problem. FSI effects may become significant for a given geometry if the time history of loading and the dynamic properties of the coupled fluid-structure system satisfy a defined (system related) relationship. Results of analyses and parametric/sensitivity studies performed for the steel containment structure of an 1100 Mwe BWR nuclear plant of Mark II configuration are presented. (Author)

  19. Simultaneous use of mark-recapture and radiotelemetry to estimate survival, movement, and capture rates

    Science.gov (United States)

    Powell, L.A.; Conroy, M.J.; Hines, J.E.; Nichols, J.D.; Krementz, D.G.

    2000-01-01

    Biologists often estimate separate survival and movement rates from radio-telemetry and mark-recapture data from the same study population. We describe a method for combining these data types in a single model to obtain joint, potentially less biased estimates of survival and movement that use all available data. We furnish an example using wood thrushes (Hylocichla mustelina) captured at the Piedmont National Wildlife Refuge in central Georgia in 1996. The model structure allows estimation of survival and capture probabilities, as well as estimation of movements away from and into the study area. In addition, the model structure provides many possibilities for hypothesis testing. Using the combined model structure, we estimated that wood thrush weekly survival was 0.989 ? 0.007 ( ?SE). Survival rates of banded and radio-marked individuals were not different (alpha hat [S_radioed, ~ S_banded]=log [S hat _radioed/ S hat _banded]=0.0239 ? 0.0435). Fidelity rates (weekly probability of remaining in a stratum) did not differ between geographic strata (psi hat=0.911 ? 0.020; alpha hat [psi11, psi22]=0.0161 ? 0.047), and recapture rates ( = 0.097 ? 0.016) banded and radio-marked individuals were not different (alpha hat [p_radioed, p_banded]=0.145 ? 0.655). Combining these data types in a common model resulted in more precise estimates of movement and recapture rates than separate estimation, but ability to detect stratum or mark-specific differences in parameters was week. We conducted simulation trials to investigate the effects of varying study designs on parameter accuracy and statistical power to detect important differences. Parameter accuracy was high (relative bias [RBIAS] inference from this model, study designs should seek a minimum of 25 animals of each marking type observed (marked or observed via telemetry) in each time period and geographic stratum.

  20. Linguistic constraints on children's overt marking of BE by dialect and age.

    Science.gov (United States)

    Roy, Joseph; Oetting, Janna B; Moland, Christy Wynn

    2013-06-01

    Overt marking of BE in nonmainstream adult dialects of English is influenced by a number of linguistic constraints, including the structure's person, number, tense, contractibility, and grammatical function. In the current study, the authors examined the effects of these constraints on overt marking of BE in children as a function of their nonmainstream English dialect and age. The data were language samples from 62 children, ages 4-6 years; 24 children spoke African American English (AAE), and 38 spoke Southern White English (SWE). Analyses included analysis of variance and logistic regression. Rates of overt marking varied by the children's dialect but not their age. Although the person, number, tense, and grammatical function of BE influenced the children's rates of marking, the nature and magnitude of the influence differed by the children's dialect. For AAE-speaking children, contractibility also influenced their marking of BE. Consistent with the adult literature, the current study showed that AAE- and SWE-speaking children marked BE in ways that differed from each other and from what has been documented for child speakers of Mainstream American English. These findings show stability in the use of BE in AAE and SWE that spans different generations and different dialect communities.

  1. NotaMark industrial laser marking system: a new security marking technology

    Science.gov (United States)

    Moreau, Vincent G.

    2004-06-01

    Up until now, the only variable alphanumeric data which could be added to banknotes was the number, applied by means of impact typographical numbering boxes. As an additional process or an alternative to this mechanical method, a non-contact laser marking process can be used offering high quality and greater levels of flexibility. For this purpose KBA-GIORI propose an exclusive laser marking solution called NotaMark. The laser marking process NotaMark is the ideal solution for applying variable data and personalizing banknotes (or any other security documents) with a very high resolution, for extremely large production volumes. A completely integrated solution has been developed comprised of laser light sources, marking head units, and covers and extraction systems. NotaMark allows the marking of variable data by removing locally and selectively, specific printed materials leaving the substrate itself untouched. A wide range of materials has already been tested extensively. NotaMark is a new security feature which is easy to identify and difficult to counterfeit, and which complies with the standard mechanical and chemical resistance tests in the security printing industry as well as with other major soiling tests. The laser marking process opens up a whole new range of design possibilities and can be used to create a primary security feature such as numbering, or to enhance the value of existing features.

  2. Infrared technique for decoding of invisible laser markings

    Science.gov (United States)

    Haferkamp, Heinz; Jaeschke, Peter; Stein, Johannes; Goede, Martin

    2002-03-01

    Counterfeiting and product piracy continues to be an important issue not only for the Western industry, but also for the society in general. Due to the drastic increase in product imitation and the request for plagiarism protection as well as for reducing thefts there is a high interest in new protection methods providing new security features. The method presented here consists of security markings which are included below paint layers. These markings are invisible for the human eye due to the non-transparency of the upper layers in the visible spectral range. However, the markings can be detected by an infrared technique taking advantage on the partial transparency of the upper paint layers in the IR-region. Metal sheets are marked using laser radiation. The beam of a Nd:YAG-laser provides a modification of the surface structure, resulting in dark markings due to the annealing effect. After coating of the laser-marked material, the markings are invisible for the bare eye. In order to read out the invisible information below the coating, an infrared reflection technique is used. The samples are illuminated with halogen lamps or infrared radiators. Many coating materials (i. e. paints) show a certain transparency in the mid-infrared region, especially between 3 - 5 micrometers . The reflected radiation is detected using an IR-camera with a sensitivity range from 3.4 - 5 micrometers . Due to the different reflection properties between the markings and their surrounding, the information can be detected.

  3. Camouflage effects of various colour-marking morphs against different microhabitat backgrounds in a polymorphic pygmy grasshopper Tetrix japonica.

    Science.gov (United States)

    Tsurui, Kaori; Honma, Atsushi; Nishida, Takayoshi

    2010-07-06

    Colour-marking polymorphism is widely distributed among cryptic species. To account for the adaptive significance of such polymorphisms, several hypotheses have been proposed to date. Although these hypotheses argue over the degree of camouflage effects of marking morphs (and the interactions between morphs and their microhabitat backgrounds), as far as we know, most empirical evidence has been provided under unnatural conditions (i.e., using artificial prey). Tetrix japonica, a pygmy grasshopper, is highly polymorphic in colour-markings and occurs in both sand and grass microhabitats. Even within a microhabitat, T. japonica is highly polymorphic. Using humans as dummy predators and printed photographs in which various morphs of grasshoppers were placed against different backgrounds, we addressed three questions to test the neutral, background heterogeneity, and differential crypsis hypotheses in four marking-type morphs: 1) do the morphs differ in the degree of crypsis in each microhabitat, 2) are different morphs most cryptic in specific backgrounds of the microhabitats, and 3) does the morph frequency reflect the degree of crypsis? The degree of camouflage differed among the four morphs; therefore, the neutral hypothesis was rejected. Furthermore, the order of camouflage advantage among morphs differed depending on the two types of backgrounds (sand and grass), although the grass background consistently provided greater camouflage effects. Thus, based on our results, we could not reject the background heterogeneity hypothesis. Under field conditions, the more cryptic morphs comprised a minority of the population. Overall, our results demonstrate that the different morphs were not equivalent in the degree of crypsis, but the degree of camouflage of the morphs was not consistent with the morph frequency. These findings suggest that trade-offs exist between the camouflage benefit of body colouration and other fitness components, providing a better understanding of

  4. Camouflage effects of various colour-marking morphs against different microhabitat backgrounds in a polymorphic pygmy grasshopper Tetrix japonica.

    Directory of Open Access Journals (Sweden)

    Kaori Tsurui

    2010-07-01

    Full Text Available Colour-marking polymorphism is widely distributed among cryptic species. To account for the adaptive significance of such polymorphisms, several hypotheses have been proposed to date. Although these hypotheses argue over the degree of camouflage effects of marking morphs (and the interactions between morphs and their microhabitat backgrounds, as far as we know, most empirical evidence has been provided under unnatural conditions (i.e., using artificial prey.Tetrix japonica, a pygmy grasshopper, is highly polymorphic in colour-markings and occurs in both sand and grass microhabitats. Even within a microhabitat, T. japonica is highly polymorphic. Using humans as dummy predators and printed photographs in which various morphs of grasshoppers were placed against different backgrounds, we addressed three questions to test the neutral, background heterogeneity, and differential crypsis hypotheses in four marking-type morphs: 1 do the morphs differ in the degree of crypsis in each microhabitat, 2 are different morphs most cryptic in specific backgrounds of the microhabitats, and 3 does the morph frequency reflect the degree of crypsis?The degree of camouflage differed among the four morphs; therefore, the neutral hypothesis was rejected. Furthermore, the order of camouflage advantage among morphs differed depending on the two types of backgrounds (sand and grass, although the grass background consistently provided greater camouflage effects. Thus, based on our results, we could not reject the background heterogeneity hypothesis. Under field conditions, the more cryptic morphs comprised a minority of the population. Overall, our results demonstrate that the different morphs were not equivalent in the degree of crypsis, but the degree of camouflage of the morphs was not consistent with the morph frequency. These findings suggest that trade-offs exist between the camouflage benefit of body colouration and other fitness components, providing a better

  5. Camouflage Effects of Various Colour-Marking Morphs against Different Microhabitat Backgrounds in a Polymorphic Pygmy Grasshopper Tetrix japonica

    Science.gov (United States)

    Tsurui, Kaori; Honma, Atsushi; Nishida, Takayoshi

    2010-01-01

    Background Colour-marking polymorphism is widely distributed among cryptic species. To account for the adaptive significance of such polymorphisms, several hypotheses have been proposed to date. Although these hypotheses argue over the degree of camouflage effects of marking morphs (and the interactions between morphs and their microhabitat backgrounds), as far as we know, most empirical evidence has been provided under unnatural conditions (i.e., using artificial prey). Methodology/Principal Findings Tetrix japonica, a pygmy grasshopper, is highly polymorphic in colour-markings and occurs in both sand and grass microhabitats. Even within a microhabitat, T. japonica is highly polymorphic. Using humans as dummy predators and printed photographs in which various morphs of grasshoppers were placed against different backgrounds, we addressed three questions to test the neutral, background heterogeneity, and differential crypsis hypotheses in four marking-type morphs: 1) do the morphs differ in the degree of crypsis in each microhabitat, 2) are different morphs most cryptic in specific backgrounds of the microhabitats, and 3) does the morph frequency reflect the degree of crypsis? Conclusions/Significance The degree of camouflage differed among the four morphs; therefore, the neutral hypothesis was rejected. Furthermore, the order of camouflage advantage among morphs differed depending on the two types of backgrounds (sand and grass), although the grass background consistently provided greater camouflage effects. Thus, based on our results, we could not reject the background heterogeneity hypothesis. Under field conditions, the more cryptic morphs comprised a minority of the population. Overall, our results demonstrate that the different morphs were not equivalent in the degree of crypsis, but the degree of camouflage of the morphs was not consistent with the morph frequency. These findings suggest that trade-offs exist between the camouflage benefit of body colouration

  6. High contrast laser marking of alumina

    International Nuclear Information System (INIS)

    Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; Val, J. del; Comesaña, R.; Lusquiños, F.; Pou, J.

    2015-01-01

    Highlights: • Laser marking of alumina using near infrared (NIR) lasers was experimentally analyzed. • Color change produced by NIR lasers is due to thermally induced oxygen vacancies. • Laser marking results obtained using NIR lasers and green laser are compared. • High contrast marks on alumina were achieved. - Abstract: Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks

  7. High contrast laser marking of alumina

    Science.gov (United States)

    Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; del Val, J.; Comesaña, R.; Lusquiños, F.; Pou, J.

    2015-05-01

    Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks.

  8. High efficiency metal marking with CO2 laser and glass marking with excimer laser

    DEFF Research Database (Denmark)

    Bastue, Jens; Olsen, Flemmming Ove

    1997-01-01

    with a thoroughly tested ray-tracing model is presented and compared with experimental results. Special emphasis is put on two different applications namely marking in metal with TEA-CO2 laser and marking in glass with excimer laser. The results are evaluated on the basis of the achievable energy enhancement......Today, mask based laser materials processing and especially marking is widely used. However, the energy efficiency in such processes is very low [1].This paper gives a review of the results, that may be obtained using the energy enhancing technique [1]. Results of simulations performed...

  9. Quantifying structural uncertainty on fault networks using a marked point process within a Bayesian framework

    Science.gov (United States)

    Aydin, Orhun; Caers, Jef Karel

    2017-08-01

    Faults are one of the building-blocks for subsurface modeling studies. Incomplete observations of subsurface fault networks lead to uncertainty pertaining to location, geometry and existence of faults. In practice, gaps in incomplete fault network observations are filled based on tectonic knowledge and interpreter's intuition pertaining to fault relationships. Modeling fault network uncertainty with realistic models that represent tectonic knowledge is still a challenge. Although methods that address specific sources of fault network uncertainty and complexities of fault modeling exists, a unifying framework is still lacking. In this paper, we propose a rigorous approach to quantify fault network uncertainty. Fault pattern and intensity information are expressed by means of a marked point process, marked Strauss point process. Fault network information is constrained to fault surface observations (complete or partial) within a Bayesian framework. A structural prior model is defined to quantitatively express fault patterns, geometries and relationships within the Bayesian framework. Structural relationships between faults, in particular fault abutting relations, are represented with a level-set based approach. A Markov Chain Monte Carlo sampler is used to sample posterior fault network realizations that reflect tectonic knowledge and honor fault observations. We apply the methodology to a field study from Nankai Trough & Kumano Basin. The target for uncertainty quantification is a deep site with attenuated seismic data with only partially visible faults and many faults missing from the survey or interpretation. A structural prior model is built from shallow analog sites that are believed to have undergone similar tectonics compared to the site of study. Fault network uncertainty for the field is quantified with fault network realizations that are conditioned to structural rules, tectonic information and partially observed fault surfaces. We show the proposed

  10. The Acquisition of English Focus Marking by Non-Native Speakers

    Science.gov (United States)

    Baker, Rachel Elizabeth

    This dissertation examines Mandarin and Korean speakers' acquisition of English focus marking, which is realized by accenting particular words within a focused constituent. It is important for non-native speakers to learn how accent placement relates to focus in English because appropriate accent placement and realization makes a learner's English more native-like and easier to understand. Such knowledge may also improve their English comprehension skills. In this study, 20 native English speakers, 20 native Mandarin speakers, and 20 native Korean speakers participated in four experiments: (1) a production experiment, in which they were recorded reading the answers to questions, (2) a perception experiment, in which they were asked to determine which word in a recording was the last prominent word, (3) an understanding experiment, in which they were asked whether the answers in recorded question-answer pairs had context-appropriate prosody, and (4) an accent placement experiment, in which they were asked which word they would make prominent in a particular context. Finally, a new group of native English speakers listened to utterances produced in the production experiment, and determined whether the prosody of each utterance was appropriate for its context. The results of the five experiments support a novel predictive model for second language prosodic focus marking acquisition. This model holds that both transfer of linguistic features from a learner's native language (L1) and features of their second language (L2) affect learners' acquisition of prosodic focus marking. As a result, the model includes two complementary components: the Transfer Component and the L2 Challenge Component. The Transfer Component predicts that prosodic structures in the L2 will be more easily acquired by language learners that have similar structures in their L1 than those who do not, even if there are differences between the L1 and L2 in how the structures are realized. The L2

  11. Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.

    Directory of Open Access Journals (Sweden)

    Pawandeep Dhami

    2010-08-01

    Full Text Available It has recently been shown that nucleosome distribution, histone modifications and RNA polymerase II (Pol II occupancy show preferential association with exons ("exon-intron marking", linking chromatin structure and function to co-transcriptional splicing in a variety of eukaryotes. Previous ChIP-sequencing studies suggested that these marking patterns reflect the nucleosomal landscape. By analyzing ChIP-chip datasets across the human genome in three cell types, we have found that this marking system is far more complex than previously observed. We show here that a range of histone modifications and Pol II are preferentially associated with exons. However, there is noticeable cell-type specificity in the degree of exon marking by histone modifications and, surprisingly, this is also reflected in some histone modifications patterns showing biases towards introns. Exon-intron marking is laid down in the absence of transcription on silent genes, with some marking biases changing or becoming reversed for genes expressed at different levels. Furthermore, the relationship of this marking system with splicing is not simple, with only some histone modifications reflecting exon usage/inclusion, while others mirror patterns of exon exclusion. By examining nucleosomal distributions in all three cell types, we demonstrate that these histone modification patterns cannot solely be accounted for by differences in nucleosome levels between exons and introns. In addition, because of inherent differences between ChIP-chip array and ChIP-sequencing approaches, these platforms report different nucleosome distribution patterns across the human genome. Our findings confound existing views and point to active cellular mechanisms which dynamically regulate histone modification levels and account for exon-intron marking. We believe that these histone modification patterns provide links between chromatin accessibility, Pol II movement and co-transcriptional splicing.

  12. Evaluation of copper for divider subassembly in MCO Mark IA and Mark IV scrap fuel baskets

    International Nuclear Information System (INIS)

    Graves, C.E.

    1997-01-01

    The K Basin Spent Nuclear Fuel (SNF) Project Multi-Canister Overpack (MCO) subprojection eludes the design and fabrication of a canister that will be used to confine, contain, and maintain fuel in a critically safe array to enable its removal from the K Basins, vacuum drying, transport, staging, hot conditioning, and interim storage (Goldinann 1997). Each MCO consists of a shell, shield plug, fuel baskets (Mark IA or Mark IV), and other incidental equipment. The Mark IA intact and scrap fuel baskets are a safety class item for criticality control and components necessary for criticality control will be constructed from 304L stainless steel. It is proposed that a copper divider subassembly be used in both Mark IA and Mark IV scrap baskets to increase the safety basis margin during cold vacuum drying. The use of copper would increase the heat conducted away from hot areas in the baskets out to the wall of the MCO by both radiative and conductive heat transfer means. Thus copper subassembly will likely be a safety significant component of the scrap fuel baskets. This report examines the structural, cost and corrosion consequences associated with using a copper subassembly in the stainless steel MCO scrap fuel baskets

  13. Experimental applications for the MARK-1 and MARK-1A pulsed ionizing radiation detection systems. Volume 3

    International Nuclear Information System (INIS)

    Harker, Y.D.; Lawrence, R.S.; Yoon, W.Y.; Lones, J.L.

    1993-12-01

    This report is the third volume in a three volume set describing the MARK series of pulsed ionizing radiation detection systems. This volume describes the MARK-1A detection system, compares it with the MARK-1 system, and describes the experimental testing of the detection systems. Volume 1 of this set presents the technical specifications for the MARK-1 detection system. Volume 2 is an operations manual specifically for the MARK-1 system, but it generally applies to the MARK-1A system as well. These detection systems operate remotely and detect photon radiation from a single or a multiple pulsed source. They contain multiple detector (eight in the MARK-1 and ten in the MARK-1A) for determination of does and incident photon effective energy. The multiple detector arrangement, having different detector sizes and shield thicknesses, provides the capability of determining the effective photon energy of the radiation spectrum. Dose measurements using these units are consistent with TLD measurements. The detection range is from 3 nanorads to 90 microrads per source burst; the response is linear over that range. Three units were built and are ready for field deployment

  14. Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system

    International Nuclear Information System (INIS)

    Kuen, Jihyeon; Woo, Eung Je; Seo, Jin Keun

    2009-01-01

    We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications

  15. Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system.

    Science.gov (United States)

    Kuen, Jihyeon; Woo, Eung Je; Seo, Jin Keun

    2009-06-01

    We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications.

  16. Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.

    Directory of Open Access Journals (Sweden)

    Ignacio de la Mora-de la Mora

    Full Text Available Deamidation, the loss of the ammonium group of asparagine and glutamine to form aspartic and glutamic acid, is one of the most commonly occurring post-translational modifications in proteins. Since deamidation rates are encoded in the protein structure, it has been proposed that they can serve as molecular clocks for the timing of biological processes such as protein turnover, development and aging. Despite the importance of this process, there is a lack of detailed structural information explaining the effects of deamidation on the structure of proteins. Here, we studied the effects of deamidation on human triosephosphate isomerase (HsTIM, an enzyme for which deamidation of N15 and N71 has been long recognized as the signal for terminal marking of the protein. Deamidation was mimicked by site directed mutagenesis; thus, three mutants of HsTIM (N15D, N71D and N15D/N71D were characterized. The results show that the N71D mutant resembles, structurally and functionally, the wild type enzyme. In contrast, the N15D mutant displays all the detrimental effects related to deamidation. The N15D/N71D mutant shows only minor additional effects when compared with the N15D mutation, supporting that deamidation of N71 induces negligible effects. The crystal structures show that, in contrast to the N71D mutant, where minimal alterations are observed, the N15D mutation forms new interactions that perturb the structure of loop 1 and loop 3, both critical components of the catalytic site and the interface of HsTIM. Based on a phylogenetic analysis of TIM sequences, we propose the conservation of this mechanism for mammalian TIMs.

  17. Enamel-based mark performance for marking Chinese mystery snail Bellamya chinensis

    Science.gov (United States)

    Wong, Alec; Allen, Craig R.; Hart, Noelle M.; Haak, Danielle M.; Pope, Kevin L.; Smeenk, Nicholas A.; Stephen, Bruce J.; Uden, Daniel R.

    2013-01-01

    The exoskeleton of gastropods provides a convenient surface for carrying marks, and i the interest of improving future marking methods our laboratory assessed the performance of an enamel paint. The endurance of the paint was also compared to other marking methods assessed in the past. We marked the shells of 30 adult Chinese mystery snails Bellamya chinensis and held them in an aquarium for 181 days. We observed no complete degradation of any enamel-paint mark during the 181 days. The enamel-paint mark was superior to a nai;-polish mark, which lasted a median of 100 days. Enamel-paint marks also have a lower rate of loss (0.00 month-1 181 days) than plastic bee tags (0.01 month-1, 57 days), gouache paint (0.07 month-1, 18.5 days), or car body paint from studies found in scientific literature. Legibility of enamel-paint marks had a median lifetime of 102 days. The use of enamel paint on the shells of gastropods is a viable option for studies lasting up to 6 months. Furthermore, visits to capture-mark-recapture site 1 year after application of enamel-paint marks on B. chinesnis shells produced several individuals on which the enamel paint was still visible, although further testing is required to clarify durability over longer periods.

  18. The national hydrologic bench-mark network

    Science.gov (United States)

    Cobb, Ernest D.; Biesecker, J.E.

    1971-01-01

    The United States is undergoing a dramatic growth of population and demands on its natural resources. The effects are widespread and often produce significant alterations of the environment. The hydrologic bench-mark network was established to provide data on stream basins which are little affected by these changes. The network is made up of selected stream basins which are not expected to be significantly altered by man. Data obtained from these basins can be used to document natural changes in hydrologic characteristics with time, to provide a better understanding of the hydrologic structure of natural basins, and to provide a comparative base for studying the effects of man on the hydrologic environment. There are 57 bench-mark basins in 37 States. These basins are in areas having a wide variety of climate and topography. The bench-mark basins and the types of data collected in the basins are described.

  19. Structuralism, Post-Structuralism, and Neo-Liberalism: Assessing Foucault's Legacy.

    Science.gov (United States)

    Olssen, Mark

    2003-01-01

    Traces Foucault's distinctive commitment to "post-structuralism." Argues that under the influence of Nietzsche, Foucault's approach marks a distinct break with structuralism in several crucial aspects. What results is a materialist post-structuralism that is also distinctively different from the post-structuralism of Derrida, Lyotard,…

  20. Structural Packaging in the Input to Language Learning: Contributions of Prosodic and Morphological Marking of Phrases to the Acquisition of Language.

    Science.gov (United States)

    Morgan, James L.; And Others

    1987-01-01

    The role of cues in language acquisition was examined in three experiments. When the cue marked the phrase structure of sentences, adult subjects successfully learned syntax. When input was identical but lacked that cue, subjects failed to learn significant portions of syntax. (Author/GDC)

  1. The chromosomal distribution of histone methylation marks in gymnosperms differs from that of angiosperms.

    Science.gov (United States)

    Fuchs, Jörg; Jovtchev, Gabriele; Schubert, Ingo

    2008-01-01

    The chromosomal distribution of seven histone methylation marks (H3K4me2, H3K9me1,2,3 and H3K27me1,2,3) was analysed in the gymnosperm species Pinus sylvestris and Picea abies. Similarly to the situation in other investigated eukaryotes, dimethylation of lysine 4 of histone H3 is restricted to euchromatin in gymnosperms. Surprisingly, also H3K9me1-a mark classified as heterochromatin-specific in angiosperms-labels the euchromatin in P. sylvestris and P. abies. The other investigated methylation marks are either equally distributed along the chromosomes, as H3K9me2 and H3K27me1 (in both species) and H3K9me3 (in P. abies), or enriched at specific types of heterochromatin, as H3K9me3 (in P. sylvestris) and H3K27me2 and H3K27me3 in both species. Although the methylation marks themselves are apparently conserved, their functional specificity within the frame of the 'epigenetic code' might have diverged during evolution.

  2. Retinal ganglion cells with distinct directional preferences differ in molecular identity, structure, and central projections.

    Science.gov (United States)

    Kay, Jeremy N; De la Huerta, Irina; Kim, In-Jung; Zhang, Yifeng; Yamagata, Masahito; Chu, Monica W; Meister, Markus; Sanes, Joshua R

    2011-05-25

    The retina contains ganglion cells (RGCs) that respond selectively to objects moving in particular directions. Individual members of a group of ON-OFF direction-selective RGCs (ooDSGCs) detect stimuli moving in one of four directions: ventral, dorsal, nasal, or temporal. Despite this physiological diversity, little is known about subtype-specific differences in structure, molecular identity, and projections. To seek such differences, we characterized mouse transgenic lines that selectively mark ooDSGCs preferring ventral or nasal motion as well as a line that marks both ventral- and dorsal-preferring subsets. We then used the lines to identify cell surface molecules, including Cadherin 6, CollagenXXVα1, and Matrix metalloprotease 17, that are selectively expressed by distinct subsets of ooDSGCs. We also identify a neuropeptide, CART (cocaine- and amphetamine-regulated transcript), that distinguishes all ooDSGCs from other RGCs. Together, this panel of endogenous and transgenic markers distinguishes the four ooDSGC subsets. Patterns of molecular diversification occur before eye opening and are therefore experience independent. They may help to explain how the four subsets obtain distinct inputs. We also demonstrate differences among subsets in their dendritic patterns within the retina and their axonal projections to the brain. Differences in projections indicate that information about motion in different directions is sent to different destinations.

  3. Mark 4A project training evaluation

    Science.gov (United States)

    Stephenson, S. N.

    1985-01-01

    A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

  4. Mark 4A project training evaluation

    Science.gov (United States)

    Stephenson, S. N.

    1985-11-01

    A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

  5. The structural and content aspects of abstracts versus bodies of full text journal articles are different.

    Science.gov (United States)

    Cohen, K Bretonnel; Johnson, Helen L; Verspoor, Karin; Roeder, Christophe; Hunter, Lawrence E

    2010-09-29

    An increase in work on the full text of journal articles and the growth of PubMedCentral have the opportunity to create a major paradigm shift in how biomedical text mining is done. However, until now there has been no comprehensive characterization of how the bodies of full text journal articles differ from the abstracts that until now have been the subject of most biomedical text mining research. We examined the structural and linguistic aspects of abstracts and bodies of full text articles, the performance of text mining tools on both, and the distribution of a variety of semantic classes of named entities between them. We found marked structural differences, with longer sentences in the article bodies and much heavier use of parenthesized material in the bodies than in the abstracts. We found content differences with respect to linguistic features. Three out of four of the linguistic features that we examined were statistically significantly differently distributed between the two genres. We also found content differences with respect to the distribution of semantic features. There were significantly different densities per thousand words for three out of four semantic classes, and clear differences in the extent to which they appeared in the two genres. With respect to the performance of text mining tools, we found that a mutation finder performed equally well in both genres, but that a wide variety of gene mention systems performed much worse on article bodies than they did on abstracts. POS tagging was also more accurate in abstracts than in article bodies. Aspects of structure and content differ markedly between article abstracts and article bodies. A number of these differences may pose problems as the text mining field moves more into the area of processing full-text articles. However, these differences also present a number of opportunities for the extraction of data types, particularly that found in parenthesized text, that is present in article bodies

  6. Multitemporal satellite data analyses for archaeological mark detection: preliminary results in Italy and Argentina

    Science.gov (United States)

    Lasaponara, Rosa; Masini, Nicola

    2014-05-01

    The current availability of very high resolution satellite data provides an excellent tool to detect and monitor archaeological marks, namely spectral and spatial anomalies linked to the presence of buried archaeological remains from a landscape view down to local scale (single site) investigations. Since the end of the nineteenth century, aerial photography has been the remote sensing tool most widely used in archaeology for surveying both surface and sub-surface archaeological remains. Aerial photography was a real "revolution" in archaeology being an excellent tool for investigations addressed at detecting underground archaeological structures through the reconnaissance of the so-called "archaeological marks" generally grouped and named as "soil","crop marks" "snow marks", and also recently "weed marks" (Lasaponara and Masini). Such marks are generally visible only from an aerial view (see detail in Lasaponara and Masini 2009, Ciminale et al. 2009, Masini and Lasaponara 2006 Lasaponara et al 2011) . In particular, soil marks are changes in soil colour or texture due to the presence of surface and shallow remains. Crop marks are changes in crop texture linked to as differences in height or colour of crops which are under stress due to lack of water or deficiencies in other nutrients caused by the presence of masonry structures in the subsoil. Crop marks can also be formed above damp and nutritious soil of buried pits and ditches. Such marks are generally visible only from an aerial view, especially during the spring season. In the context of the Project "Remote sensing technologies applied to the management of natural and cultural heritage in sites located in Italy and Argentina: from risk monitoring to mitigatin startegies P@an_sat", funded by the Italian Ministry of Foreign Affair, we tested the capability of multitemporal data, from active and passive satellite sensors, in the detection of "archaeological marks". The areas of interested were selected from

  7. COMPUTER HARDWARE MARKING

    CERN Multimedia

    Groupe de protection des biens

    2000-01-01

    As part of the campaign to protect CERN property and for insurance reasons, all computer hardware belonging to the Organization must be marked with the words 'PROPRIETE CERN'.IT Division has recently introduced a new marking system that is both economical and easy to use. From now on all desktop hardware (PCs, Macintoshes, printers) issued by IT Division with a value equal to or exceeding 500 CHF will be marked using this new system.For equipment that is already installed but not yet marked, including UNIX workstations and X terminals, IT Division's Desktop Support Service offers the following services free of charge:Equipment-marking wherever the Service is called out to perform other work (please submit all work requests to the IT Helpdesk on 78888 or helpdesk@cern.ch; for unavoidable operational reasons, the Desktop Support Service will only respond to marking requests when these coincide with requests for other work such as repairs, system upgrades, etc.);Training of personnel designated by Division Leade...

  8. Strength analysis and optimization of writing mechanism of steel billet marking machine

    Directory of Open Access Journals (Sweden)

    Fu Min

    2017-01-01

    Full Text Available According to steel billet marking theory of plasma arc nicking, the paper designs a dual laser ranging marking machine against online marking of special steel billet and realizes multi-character marking of the end face of hot steel billet. Writing mechanism bases on the rectangular coordinates marking form, Z axis adopts cantilever structure. It completes the overall marking task utilizing the synergy of KK module in X axis, Y axis and Z axis. It makes modal analysis on the writing mechanism model established by Pro/Enginner utilizing ANSYS Workbench at the position of X1Y1Z1, and obtains the first six order modal frequency and analyzes the vibration in the writing process. Moreover, the paper analyzes the static structure of the cantilever of writing mechanism, computes its maximum stress and total deformation. To make the writing mechanism reach the target of light weight, the paper optimizes Z-axis cantilever of writing mechanism. According to the analysis, it is known that the optimized Z-axis cantilever of the writing mechanism still meets the strength and rigidity requirement and total mass declines approximately 30%.

  9. Survival and reproduction of radio-marked adult spotted owls.

    Science.gov (United States)

    C.C. Foster; E.D. Forsman; E.C. Meslow; G.S. Miller; J.A. Reid; F.F. Wagner; A.B. Carey; J.B. Lint

    1992-01-01

    We compared survival, reproduction, and body mass of radio-marked and non radio-marked spotted owls (Strix occidentalis) to determine if backpack radios influenced reproduction or survival. In most study areas and years, there were no differences (P > 0.05) in survival of males and females or in survival of radio-marked versus banded owls. There...

  10. Coupled and extended quintessence: Theoretical differences and structure formation

    International Nuclear Information System (INIS)

    Pettorino, Valeria; Baccigalupi, Carlo

    2008-01-01

    The case of a coupling between dark energy and matter [coupled quintessence (CQ)] or gravity [extended quintessence (EQ)] has recently attracted a deep interest and has been widely investigated both in the Einstein and in the Jordan frames (EF, JF), within scalar-tensor theories. Focusing on the simplest models proposed so far, in this paper we study the relation existing between the two scenarios, isolating the Weyl scaling which allows one to express them in the EF and JF. Moreover, we perform a comparative study of the behavior of linear perturbations in both scenarios, which turn out to behave in a markedly different way. In particular, while the clustering is enhanced in the considered CQ models with respect to the corresponding quintessence ones where the coupling is absent and to the ordinary cosmologies with a cosmological constant and cold dark matter (ΛCDM), structures in EQ models may grow slower. This is likely to have direct consequences on the inner properties of nonlinear structures, like cluster concentration, as well as on the weak lensing shear on large scales. Finally, we specialize our study for interfacing linear dynamics and N-body simulations in these cosmologies, giving a recipe for the corrections to be included in N-body codes in order to take into account the modifications to the expansion rate, growth of structures, and strength of gravity

  11. Distinguishing butchery cut marks from crocodile bite marks through machine learning methods.

    Science.gov (United States)

    Domínguez-Rodrigo, Manuel; Baquedano, Enrique

    2018-04-10

    All models of evolution of human behaviour depend on the correct identification and interpretation of bone surface modifications (BSM) on archaeofaunal assemblages. Crucial evolutionary features, such as the origin of stone tool use, meat-eating, food-sharing, cooperation and sociality can only be addressed through confident identification and interpretation of BSM, and more specifically, cut marks. Recently, it has been argued that linear marks with the same properties as cut marks can be created by crocodiles, thereby questioning whether secure cut mark identifications can be made in the Early Pleistocene fossil record. Powerful classification methods based on multivariate statistics and machine learning (ML) algorithms have previously successfully discriminated cut marks from most other potentially confounding BSM. However, crocodile-made marks were marginal to or played no role in these comparative analyses. Here, for the first time, we apply state-of-the-art ML methods on crocodile linear BSM and experimental butchery cut marks, showing that the combination of multivariate taphonomy and ML methods provides accurate identification of BSM, including cut and crocodile bite marks. This enables empirically-supported hominin behavioural modelling, provided that these methods are applied to fossil assemblages.

  12. Radio-marking and in vivo imagery of oligonucleotides

    International Nuclear Information System (INIS)

    Kuehnast, Bertrand

    2000-01-01

    This research thesis is part of activities aimed at the development of new molecules like oligonucleotides. Its first objective was the development and validation of a marking method with fluorine-18 of oligonucleotides for their in-vivo pharmacological assessment with positron emission tomography (PET). Further investigations addressed the use of iodine-125 for oligonucleotide marking purpose. This radio-marking, and in vivo and ex vivo imagery techniques are described, and their potential is highlighted for the pharmacological assessment of different oligonucleotides

  13. German Children’s Use of Word Order and Case Marking to Interpret Simple and Complex Sentences: Testing Differences Between Constructions and Lexical Items

    Science.gov (United States)

    Brandt, Silke; Lieven, Elena; Tomasello, Michael

    2016-01-01

    ABSTRACT Children and adults follow cues such as case marking and word order in their assignment of semantic roles in simple transitives (e.g., the dog chased the cat). It has been suggested that the same cues are used for the interpretation of complex sentences, such as transitive relative clauses (RCs) (e.g., that’s the dog that chased the cat) (Bates, Devescovi, & D’Amico, 1999). We used a pointing paradigm to test German-speaking 3-, 4-, and 6-year-old children’s sensitivity to case marking and word order in their interpretation of simple transitives and transitive RCs. In Experiment 1, case marking was ambiguous. The only cue available was word order. In Experiment 2, case was marked on lexical NPs or demonstrative pronouns. In Experiment 3, case was marked on lexical NPs or personal pronouns. Whereas the younger children mainly followed word order, the older children were more likely to base their interpretations on the more reliable case-marking cue. In most cases, children from both age groups were more likely to use these cues in their interpretation of simple transitives than in their interpretation of transitive RCs. Finally, children paid more attention to nominative case when it was marked on first-person personal pronouns than when it was marked on third-person lexical NPs or demonstrative pronouns, such as der Löwe ‘the-NOM lion’ or der ‘he-NOM.’ They were able to successfully integrate this case-marking cue in their sentence processing even when it appeared late in the sentence. We discuss four potential reasons for these differences across development, constructions, and lexical items. (1) Older children are relatively more sensitive to cue reliability. (2) Word order is more reliable in simple transitives than in transitive RCs. (3) The processing of case marking might initially be item-specific. (4) The processing of case marking might depend on its saliency and position in the sentence. PMID:27019652

  14. Perception of scent over-marks by golden hamsters (Mesocricetus auratus): novel mechanisms for determining which individual's mark is on top.

    Science.gov (United States)

    Johnston, R E; Bhorade, A

    1998-09-01

    Hamsters preferentially remember or value the top scent of a scent over-mark. What cues do they use to do this? Using habituation-discrimination techniques, we exposed male golden hamsters (Mesocricetus auratus) on 3 to 4 trials to genital over-marks from 2 females and then tested subjects for their familiarity with these 2 scents compared with that of a novel female's secretion. Preferential memory for 1 of the 2 individuals' scents did not occur if the 2 marks did not overlap or did not overlap but differed in age, but it did occur if a region of overlap existed or 1 mark apparently occluded another (but did not overlap it). Thus, hamsters use regions of overlap and the spatial configuration of scents to evaluate over-marks. These phenomena constitute evidence for previously unsuspected perceptual abilities, including olfactory scene analysis, which is analogous to visual and auditory scene analysis.

  15. Identification markings for gemstones

    International Nuclear Information System (INIS)

    Dreschhoff, G.A.M.; Zeller, E.J.

    1980-01-01

    A method is described of providing permanent identification markings to gemstones such as diamond crystals by irradiating the cooled gemstone with protons in the desired pattern. The proton bombardment results in a reaction limited to a defined plane and converting the bombarded area of the plane into a different crystal lattice from that of the preirradiated stone. (author)

  16. Mark Tompkins Canaccord

    OpenAIRE

    Mark Tompkins Canaccord

    2018-01-01

    Mark Tompkins Canaccord is a senior technologist for ecosystem and water resources management in SEC SAID Oakland, California office. In his career which lasts over fifteen years Mark has worked on project involving lake restorations, clean water engineering, ecological engineering and management, hydrology, hydraulics, sediment transport and other projects for environmental planning all over the country. Mark Tompkins Canaccord tries to blend his skills of planning and engineering with s...

  17. Reconfiguring trade mark law

    DEFF Research Database (Denmark)

    Elsmore, Matthew James

    2013-01-01

    -border setting, with a particular focus on small business and consumers. The article's overall message is to call for a rethink of received wisdom suggesting that trade marks are effective trade-enabling devices. The case is made for reassessing how we think about European trade mark law.......First, this article argues that trade mark law should be approached in a supplementary way, called reconfiguration. Second, the article investigates such a reconfiguration of trade mark law by exploring the interplay of trade marks and service transactions in the Single Market, in the cross...

  18. Parts Quality Management: Direct Part Marking via Data Matrix Symbols for Mission Assurance

    Science.gov (United States)

    Moss, Chantrice

    2013-01-01

    A United States Government Accountability Office (GAO) review of twelve NASA programs found widespread parts quality problems contributing to significant cost overruns, schedule delays, and reduced system reliability. Direct part-marking with Data Matrix symbols could significantly improve the quality of inventory control and parts lifecycle management. This paper examines the feasibility of using 15 marking technologies for use in future NASA programs. A structural analysis is based on marked material type, operational environment (e.g., ground, suborbital, orbital), durability of marks, ease of operation, reliability, and affordability. A cost-benefits analysis considers marking technology (data plates, label printing, direct part marking) and marking types (two-dimensional machine-readable, human-readable). Previous NASA parts marking efforts and historical cost data are accounted for, including in-house vs. outsourced marking. Some marking methods are still under development. While this paper focuses on NASA programs, results may be applicable to a variety of industrial environments.

  19. Parts Quality Management: Direct Part Marking of Data Matrix Symbol for Mission Assurance

    Science.gov (United States)

    Moss, Chantrice; Chakrabarti, Suman; Scott, David W.

    2013-01-01

    A United States Government Accountability Office (GAO) review of twelve NASA programs found widespread parts quality problems contributing to significant cost overruns, schedule delays, and reduced system reliability. Direct part marking with Data Matrix symbols could significantly improve the quality of inventory control and parts lifecycle management. This paper examines the feasibility of using direct part marking technologies for use in future NASA programs. A structural analysis is based on marked material type, operational environment (e.g., ground, suborbital, Low Earth Orbit), durability of marks, ease of operation, reliability, and affordability. A cost-benefits analysis considers marking technology (label printing, data plates, and direct part marking) and marking types (two-dimensional machine-readable, human-readable). Previous NASA parts marking efforts and historical cost data are accounted for, including inhouse vs. outsourced marking. Some marking methods are still under development. While this paper focuses on NASA programs, results may be applicable to a variety of industrial environments.

  20. Cultural and ethnic differences in the acceptance or rejection of liposuction instrumentation entrance marks.

    Science.gov (United States)

    Field, Lawrence M

    2007-01-01

    The acceptance of visible marks on the skin as a result of surgical procedures varies by the necessity of the procedure (ie, cosmetic or not) and by the cultural interpretation of those sequelae. As liposuction has become the most commonly performed major cosmetic procedure in the US, and perhaps throughout the world, the visible stigmata resulting from the surgical invasion may be of major consequence to some while they remain of little or no consequence to others. This article explores the national, cultural, racial, and ethnic variations in the acceptance or rejection of visible marks on the skin in several parts of world.

  1. Microstructure of gross chill-mark defect in a glass-ceramic preform

    International Nuclear Information System (INIS)

    Spears, R.K.

    1980-01-01

    The microstructure of a vacuum tube glass-ceramic preform containing gross chill-marks on the top and bottom surfaces as well as on the sides was analyzed. The preform was ceramed in a graphite mold and examined using SEM. The glass-ceramic had an extremely dense and fine crystalline structure except where the chill-marks were located. In those areas of matrix glass following the chill-mark plane were evident. It is concluded that gross chill-marks will affect the microstructure by disrupting the chemistry or nucleating characteristics in such a way that a chill-mark regon would appear to be depleted of crystallites. Although the crystallites in this region are larger, the quantity is lower than in the base glass-ceramic. The affected area caused by the chill-mark left a band of matrix glass approximately 100 μ wide. It is believed that planar defects of this size will degrade the mechanical and permeation properties of the glass-ceramic

  2. Bench-marking beam-beam simulations using coherent quadrupole effects

    International Nuclear Information System (INIS)

    Krishnagopal, S.; Chin, Y.H.

    1992-06-01

    Computer simulations are used extensively in the study of the beam-beam interaction. The proliferation of such codes raises the important question of their reliability, and motivates the development of a dependable set of bench-marks. We argue that rather than detailed quantitative comparisons, the ability of different codes to predict the same qualitative physics should be used as a criterion for such bench-marks. We use the striking phenomenon of coherent quadrupole oscillations as one such bench-mark, and demonstrate that our codes do indeed observe this behaviour. We also suggest some other tests that could be used as bench-marks

  3. Bench-marking beam-beam simulations using coherent quadrupole effects

    International Nuclear Information System (INIS)

    Krishnagopal, S.; Chin, Y.H.

    1992-01-01

    Computer simulations are used extensively in the study of the beam-beam interaction. The proliferation of such codes raises the important question of their reliability, and motivates the development of a dependable set of bench-marks. We argue that rather than detailed quantitative comparisons, the ability of different codes to predict the same qualitative physics should be used as a criterion for such bench-marks. We use the striking phenomenon of coherent quadrupole oscillations as one such bench-mark, and demonstrate that our codes do indeed observe this behavior. We also suggest some other tests that could be used as bench-marks

  4. Object marking in Swahili: Definiteness, specificity, or both ...

    African Journals Online (AJOL)

    This article examines the role of object marking in relation to definiteness and specificity in Swahili. Object marking in general has attracted the attention of many scholars in the field of Bantu linguistics due to the complex nature of object markers (OMs) and varying functions they fulfil in Bantu. Opinions differ on the role of ...

  5. BWR Mark I pressure suppression study: bench mark experiments

    International Nuclear Information System (INIS)

    Lai, W.; McCauley, E.W.

    1977-01-01

    Computer simulations representative of the wetwell of Mark I BWR's have predicted pressures and related phenomena. However, calculational predictions for purposes of engineering decision will be possible only if the code can be verified, i.e., shown to compute in accord with measured values. Described in the report is a set of single downcomer spherical flask bench mark experiments designed to produce quantitative data to validate various air-water dynamic computations; the experiments were performed since relevant bench mark data were not available from outside sources. Secondary purposes of the study were to provide a test bed for the instrumentation and post-experiment data processing techniques to be used in the Laboratory's reactor safety research program and to provide additional masurements for the air-water scaling study

  6. Elemental marking of arthropod pests in agricultural systems: single and multigenerational marking

    Science.gov (United States)

    Jane Leslie Hayes

    1991-01-01

    Use of elemental markers to study movement of arthropod pests of field crops is reviewed. Trace elements, rubidium (Rb) and cesium (Cs), have provided a nondisruptive method of marking natural adult populations via developmental stage consumption of treated host plants. Multigenerational marking occurs with the transfer of elemental markers from marked adults to...

  7. Detection and recognition of road markings in panoramic images

    Science.gov (United States)

    Li, Cheng; Creusen, Ivo; Hazelhoff, Lykele; de With, Peter H. N.

    2015-03-01

    Detection of road lane markings is attractive for practical applications such as advanced driver assistance systems and road maintenance. This paper proposes a system to detect and recognize road lane markings in panoramic images. The system can be divided into four stages. First, an inverse perspective mapping is applied to the original panoramic image to generate a top-view road view, in which the potential road markings are segmented based on their intensity difference compared to the surrounding pixels. Second, a feature vector of each potential road marking segment is extracted by calculating the Euclidean distance between the center and the boundary at regular angular steps. Third, the shape of each segment is classified using a Support Vector Machine (SVM). Finally, by modeling the lane markings, previous falsely detected segments can be rejected based on their orientation and position relative to the lane markings. Our experiments show that the system is promising and is capable of recognizing 93%, 95% and 91% of striped line segments, blocks and arrows respectively, as well as 94% of the lane markings.

  8. Differential Signature of the Centrosomal MARK4 Isoforms in Glioma

    Directory of Open Access Journals (Sweden)

    Ivana Magnani

    2011-01-01

    Full Text Available Background: MAP/microtubule affinity-regulating kinase 4 (MARK4 is a serine-threonine kinase expressed in two spliced isoforms, MARK4L and MARK4S, of which MARK4L is a candidate for a role in neoplastic transformation. Methods: We performed mutation analysis to identify sequence alterations possibly affecting MARK4 expression. We then investigated the MARK4L and MARK4S expression profile in 21 glioma cell lines and 36 tissues of different malignancy grades, glioblastoma-derived cancer stem cells (GBM CSCs and mouse neural stem cells (NSCs by real-time PCR, immunoblotting and immunohistochemistry. We also analyzed the sub-cellular localisation of MARK4 isoforms in glioma and normal cell lines by immunofluorescence. Results: Mutation analysis rules out sequence variations as the cause of the altered MARK4 expression in glioma. Expression profiling confirms that MARK4L is the predominant isoform, whereas MARK4S levels are significantly decreased in comparison and show an inverse correlation with tumour grade. A high MARK4L/MARK4S ratio also characterizes undifferentiated cells, such as GBM CSCs and NSCs. Accordingly, only MARK4L is expressed in brain neurogenic regions. Moreover, while both MARK4 isoforms are localised to the centrosome and midbody in glioma and normal cells, the L isoform exhibits an additional nucleolar localisation in tumour cells. Conclusions: The observed switch towards MARK4L suggests that the balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis. Moreover, the MARK4L nucleolar localisation in tumour cells features this MARK4 isoform as a nucleolus-associated tumour marker.

  9. Experimental investigations on fiber laser color marking of steels

    Energy Technology Data Exchange (ETDEWEB)

    Amara, E.H., E-mail: amara@cdta.dz; Haïd, F.; Noukaz, A.

    2015-10-01

    Highlights: • We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. • We have used a home-made marking device composed of a pulsed fiber laser and galvanometric mirrors. • Both commercial and elaborated in laboratory steels have been used as samples. • The experiments have been performed for different laser beam operating parameters, under normal atmospheric conditions. • The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. - Abstract: We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. A home-made marking device using a pulsed fiber laser has been used to treat steel samples under different laser beam operating parameters, for different compositions of the processed steel, and at normal atmospheric conditions. The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. The results show the influence of the operating parameters on the obtained colors.

  10. Experimental investigations on fiber laser color marking of steels

    International Nuclear Information System (INIS)

    Amara, E.H.; Haïd, F.; Noukaz, A.

    2015-01-01

    Highlights: • We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. • We have used a home-made marking device composed of a pulsed fiber laser and galvanometric mirrors. • Both commercial and elaborated in laboratory steels have been used as samples. • The experiments have been performed for different laser beam operating parameters, under normal atmospheric conditions. • The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. - Abstract: We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. A home-made marking device using a pulsed fiber laser has been used to treat steel samples under different laser beam operating parameters, for different compositions of the processed steel, and at normal atmospheric conditions. The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. The results show the influence of the operating parameters on the obtained colors

  11. Structure of xanthan gum and cell ultrastructure at different times of alkali stress.

    Science.gov (United States)

    Luvielmo, Márcia de Mello; Borges, Caroline Dellinghausen; Toyama, Daniela de Oliveira; Vendruscolo, Claire Tondo; Scamparini, Adilma Regina Pippa

    2016-01-01

    The effect of alkali stress on the yield, viscosity, gum structure, and cell ultrastructure of xanthan gum was evaluated at the end of fermentation process of xanthan production by Xanthomonas campestris pv. manihotis 280-95. Although greater xanthan production was observed after a 24h-alkali stress process, a lower viscosity was observed when compared to the alkali stress-free gum, regardless of the alkali stress time. However, this outcome is not conclusive as further studies on gum purification are required to remove excess sodium, verify the efficiency loss and the consequent increase in the polymer viscosity. Alkali stress altered the structure of xanthan gum from a polygon-like shape to a star-like form. At the end of the fermentation, early structural changes in the bacterium were observed. After alkali stress, marked structural differences were observed in the cells. A more vacuolated cytoplasm and discontinuities in the membrane cells evidenced the cell lysis. Xanthan was observed in the form of concentric circles instead of agglomerates as observed prior to the alkali stress. Copyright © 2015 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  12. Damage analysis of TRIGA MARK II Bandung reactor tank material structure

    International Nuclear Information System (INIS)

    Soedardjo; Sumijanto

    2000-01-01

    Damage of Triga Mark II Bandung reactor tank material structure has been analyzed. The analysis carried out was based on ultrasonic inspection result in 1996 and the monthly reports of reactor operation by random data during 1988 up to 1995. Ultrasonic test data had shown that thinning processes on south and west region of reactor out side wall at upper part of water level had happened. Reactor operation data had shown the demineralized water should be added monthly to the reactor and bulk shielding water tank. Both reactor and bulk shielding tank are shielded by concrete of Portland type I cement consisting of CaO content about 58-68 %. The analysis result shows that the reaction between CaO and seepage water from bulk shielding wall had taken place and consequently the reactor out sidewall surroundings became alkaline. Based on Pourbaix diagram, the aluminum reactor tank made of aluminum alloy 6061 T6 would be corroded easily at pH equal an greater than 8.6. The passive layer AI 2 O 3 aluminum metal surface would be broken due to water reaction taken place continuously at high pH and produces hydrogen gas. The light hydrogen gas would expand the concrete cement and its expanding power would open the passive layer of aluminum metal upper tank. The water sea pages from adding water into reactor tank could indicate the upper water level tank corrosion is worse than the lower water level tank. (author)

  13. [Comparison of bite marks and teeth features using 2D and 3D methods].

    Science.gov (United States)

    Lorkiewicz-Muszyńska, Dorota; Glapiński, Mariusz; Zaba, Czesław; Łabecka, Marzena

    2011-01-01

    The nature of bite marks is complex. They are found at the scene of crime on different materials and surfaces - not only on human body and corpse, but also on food products and material objects. Human bites on skin are sometimes difficult to interpret and to analyze because of the specific character of skin--elastic and distortable--and because different areas of human body have different surfaces and curvatures. A bite mark left at the scene of crime can be a highly helpful way to lead investigators to criminals. The study was performed to establish: 1) whether bite marks exhibit variations in the accuracy of impressions on different materials, 2) whether it is possible to use the 3D method in the process of identifying an individual based on the comparison of bite marks revealed at the scene, and 3D scans of dental casts, 3) whether application of the 3D method allows for elimination of secondary photographic distortion of bite marks. The authors carried out experiments on simulated cases. Five volunteers bit various materials with different surfaces. Experimental bite marks were collected with emphasis on differentiations of materials. Subsequently, dental impressions were taken from five volunteers in order to prepare five sets of dental casts (the maxilla and mandible. The biting edges of teeth were impressed in wax to create an imprint. The samples of dental casts, corresponding wax bite impressions and bite marks from different materials were scanned with 2D and 3D scanners and photographs were taken. All of these were examined in detail and then compared using different methods (2D and 3D). 1) Bite marks exhibit variations in accuracy of impression on different materials. The most legible reproduction of bite marks was seen on cheese. 2) In comparison of bite marks, the 3D method and 3D scans of dental casts are highly accurate. 3) The 3D method helps to eliminate secondary photographic distortion of bite marks.

  14. Electromagnetic energy vortex associated with sub-wavelength plasmonic Taiji marks.

    Science.gov (United States)

    Chen, Wei Ting; Wu, Pin Chieh; Chen, Chen Jung; Chung, Hung-Yi; Chau, Yuan-Fong; Kuan, Chieh-Hsiung; Tsai, Din Ping

    2010-09-13

    The Taiji symbol is a very old schematic representation of two opposing but complementary patterns in oriental civilization. Using electron beam lithography, we fabricated an array of 70 × 70 gold Taiji marks with 30 nm thickness and a total area of 50 × 50 µm(2) on a fused silica substrate. The diameter of each Taiji mark is 500 nm, while the period of the array is 700 nm. Here we present experimental as well as numerical simulation results pertaining to plasmonic resonances of several Taiji nano-structures under normal illumination. We have identified a Taiji structure with a particularly interesting vortex-like Poynting vector profile, which could be attributed to the special shape and dimensions of the Taiji symbol.

  15. A computational model for histone mark propagation reproduces the distribution of heterochromatin in different human cell types.

    Science.gov (United States)

    Schwämmle, Veit; Jensen, Ole Nørregaard

    2013-01-01

    Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which consists of a histone octamer with DNA wrapped around it. Histone proteins are implicated in the regulation of eukaryote genes and they carry numerous reversible post-translational modifications that control DNA-protein interactions and the recruitment of chromatin binding proteins. Heterochromatin, the transcriptionally inactive part of the genome, is densely packed and contains histone H3 that is methylated at Lys 9 (H3K9me). The propagation of H3K9me in nucleosomes along the DNA in chromatin is antagonizing by methylation of H3 Lysine 4 (H3K4me) and acetylations of several lysines, which is related to euchromatin and active genes. We show that the related histone modifications form antagonized domains on a coarse scale. These histone marks are assumed to be initiated within distinct nucleation sites in the DNA and to propagate bi-directionally. We propose a simple computer model that simulates the distribution of heterochromatin in human chromosomes. The simulations are in agreement with previously reported experimental observations from two different human cell lines. We reproduced different types of barriers between heterochromatin and euchromatin providing a unified model for their function. The effect of changes in the nucleation site distribution and of propagation rates were studied. The former occurs mainly with the aim of (de-)activation of single genes or gene groups and the latter has the power of controlling the transcriptional programs of entire chromosomes. Generally, the regulatory program of gene transcription is controlled by the distribution of nucleation sites along the DNA string.

  16. Lujan Mark-4

    Energy Technology Data Exchange (ETDEWEB)

    Mocko, Michael Jeffrey [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavorka, Lukas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Koehler, Paul E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-13

    This is a review of Mark-IV target neutronics design. It involved the major redesign of the upper tier, offering harder neutron spectra for upper-tier FPs; a redesign of the high-resolution (HR) moderator; and a preservation of the rest of Mark-III features.

  17. Marked colour divergence in the gliding membranes of a tropical lizard mirrors population differences in the colour of falling leaves

    OpenAIRE

    Klomp, D. A.; Stuart-Fox, D.; Das, I.; Ord, T. J.

    2014-01-01

    Populations of the Bornean gliding lizard, Draco cornutus, differ markedly in the colour of their gliding membranes. They also differ in local vegetation type (mangrove forest versus lowland rainforest) and consequently, the colour of falling leaves (red and brown/black in mangrove versus green, brown and black in rainforest). We show that the gliding membranes of these lizards closely match the colours of freshly fallen leaves in the local habitat as they appear to the visual system of birds...

  18. Minimal Marking: A Success Story

    Science.gov (United States)

    McNeilly, Anne

    2014-01-01

    The minimal-marking project conducted in Ryerson's School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The "minimal-marking" concept (Haswell, 1983), which requires…

  19. A Novel Marking Reader for Progressive Addition Lenses Based on Gabor Holography.

    Science.gov (United States)

    Perucho, Beatriz; Picazo-Bueno, José Angel; Micó, Vicente

    2016-05-01

    Progressive addition lenses (PALs) are marked with permanent engraved marks (PEMs) at standardized locations. Permanent engraved marks are very useful through the manufacturing and mounting processes, act as locator marks to re-ink the removable marks, and contain useful information about the PAL. However, PEMs are often faint and weak, obscured by scratches, partially occluded, and difficult to recognize on tinted lenses or with antireflection or scratch-resistant coatings. The aim of this article is to present a new generation of portable marking reader based on an extremely simplified concept for visualization and identification of PEMs in PALs. Permanent engraved marks on different PALs are visualized using classical Gabor holography as underlying principle. Gabor holography allows phase sample visualization with adjustable magnification and can be implemented in either classical or digital versions. Here, visual Gabor holography is used to provide a magnified defocused image of the PEMs onto a translucent visualization screen where the PEM is clearly identified. Different types of PALs (conventional, personalized, old and scratched, sunglasses, etc.) have been tested to visualize PEMs with the proposed marking reader. The PEMs are visible in every case, and variable magnification factor can be achieved simply moving up and down the PAL in the instrument. In addition, a second illumination wavelength is also tested, showing the applicability of this novel marking reader for different illuminations. A new concept of marking reader ophthalmic instrument has been presented and validated in the laboratory. The configuration involves only a commercial-grade laser diode and a visualization screen for PEM identification. The instrument is portable, economic, and easy to use, and it can be used for identifying patient's current PAL model and for marking removable PALs again or finding test points regardless of the age of the PAL, its scratches, tints, or coatings.

  20. Mark Stock | NREL

    Science.gov (United States)

    Stock Mark Stock Scientific Visualization Specialist Mark.Stock@nrel.gov | 303-275-4174 Dr. Stock , virtual reality, parallel computing, and manipulation of large spatial data sets. As an artist, he creates . Stock built the SUNLIGHT artwork that is installed on the Webb Building in downtown Denver. In addition

  1. Multiplexing clonality: combining RGB marking and genetic barcoding

    Science.gov (United States)

    Cornils, Kerstin; Thielecke, Lars; Hüser, Svenja; Forgber, Michael; Thomaschewski, Michael; Kleist, Nadja; Hussein, Kais; Riecken, Kristoffer; Volz, Tassilo; Gerdes, Sebastian; Glauche, Ingmar; Dahl, Andreas; Dandri, Maura; Roeder, Ingo; Fehse, Boris

    2014-01-01

    RGB marking and DNA barcoding are two cutting-edge technologies in the field of clonal cell marking. To combine the virtues of both approaches, we equipped LeGO vectors encoding red, green or blue fluorescent proteins with complex DNA barcodes carrying color-specific signatures. For these vectors, we generated highly complex plasmid libraries that were used for the production of barcoded lentiviral vector particles. In proof-of-principle experiments, we used barcoded vectors for RGB marking of cell lines and primary murine hepatocytes. We applied single-cell polymerase chain reaction to decipher barcode signatures of individual RGB-marked cells expressing defined color hues. This enabled us to prove clonal identity of cells with one and the same RGB color. Also, we made use of barcoded vectors to investigate clonal development of leukemia induced by ectopic oncogene expression in murine hematopoietic cells. In conclusion, by combining RGB marking and DNA barcoding, we have established a novel technique for the unambiguous genetic marking of individual cells in the context of normal regeneration as well as malignant outgrowth. Moreover, the introduction of color-specific signatures in barcodes will facilitate studies on the impact of different variables (e.g. vector type, transgenes, culture conditions) in the context of competitive repopulation studies. PMID:24476916

  2. Reliability of different mark-recapture methods for population size estimation tested against reference population sizes constructed from field data.

    Directory of Open Access Journals (Sweden)

    Annegret Grimm

    Full Text Available Reliable estimates of population size are fundamental in many ecological studies and biodiversity conservation. Selecting appropriate methods to estimate abundance is often very difficult, especially if data are scarce. Most studies concerning the reliability of different estimators used simulation data based on assumptions about capture variability that do not necessarily reflect conditions in natural populations. Here, we used data from an intensively studied closed population of the arboreal gecko Gehyra variegata to construct reference population sizes for assessing twelve different population size estimators in terms of bias, precision, accuracy, and their 95%-confidence intervals. Two of the reference populations reflect natural biological entities, whereas the other reference populations reflect artificial subsets of the population. Since individual heterogeneity was assumed, we tested modifications of the Lincoln-Petersen estimator, a set of models in programs MARK and CARE-2, and a truncated geometric distribution. Ranking of methods was similar across criteria. Models accounting for individual heterogeneity performed best in all assessment criteria. For populations from heterogeneous habitats without obvious covariates explaining individual heterogeneity, we recommend using the moment estimator or the interpolated jackknife estimator (both implemented in CAPTURE/MARK. If data for capture frequencies are substantial, we recommend the sample coverage or the estimating equation (both models implemented in CARE-2. Depending on the distribution of catchabilities, our proposed multiple Lincoln-Petersen and a truncated geometric distribution obtained comparably good results. The former usually resulted in a minimum population size and the latter can be recommended when there is a long tail of low capture probabilities. Models with covariates and mixture models performed poorly. Our approach identified suitable methods and extended options to

  3. Mark Twain: inocente ou pecador? = Mark Twain: innocent or sinner?

    Directory of Open Access Journals (Sweden)

    Heloisa Helou Doca

    2009-01-01

    Full Text Available A leitura cuidadosa do texto do “Tratado de Paris”, em 1900, leva Mark Twain a concluir que a intenção política norte-americana era, claramente, a de subjugação. Declara-se, abertamente, antiimperialista, nesse momento, apesar das inúmeras críticasrecebidas por antagonistas políticos que defendiam o establishment dos Estados Unidos. Após viajar para a Europa e Oriente, em 1867, como correspondente do jornal Daily Alta Califórnia, Mark Twain publica, em 1869, seu relato de viagem, The Innocents Abroad or TheNew Pilgrim’s Progress. Nosso estudo demonstra que o autor, apesar das diversas máscaras usadas em seus relatos, narra histórias, culturas e tradições, tanto da Europa quanto do Oriente, já com os olhos bem abertos pelo viés antiimperialista. Faz uso da paródia, sátira, ironia e humor para dessacralizar impérios, monarcas e a Igreja que subjugavam os mais fracos, iluminando, desde então, os estudos sobre culturas. Nosso estudo, outrossim, faz uma reflexão sobre cultura, tradição e o olhar do viajante, justificando o “olhar inocente” do narrador em seu relato.After carefully reading the Treaty of Paris in 1900, Mark Twain concluded that the goal of U.S. policy was clearly one ofsubjugation. He openly declared himself an anti-imperialist at that time, in spite of the numerous criticisms he received from political opponents who supported the United States status quo. After traveling to Europe and the East in 1867 as a correspondent for The DailyAlta California newspaper, Mark Twain published his travel report, The Innocents Abroad or The New Pilgrim’s Progress in 1869. Our study demonstrates that the author, in spite of using different guises in his reports, narrated histories, cultures and traditions – from both Europe and the East – with a viewpoint already imbued by his anti-imperialistic ideals. Twain made use of parody, satire, irony and humor within his texts in order to desecrate empires,monarchs and

  4. Structural-Semantic Peculiarities of Derogatory Marked Ethnonyms of the Canadian, Australian and New Zealand English Language

    Directory of Open Access Journals (Sweden)

    Tsebrovskaya Tatyana Alexandrovna

    2016-06-01

    Full Text Available The article studies word formation of the derogatory marked ethnonyms (DME of the Canadian, Australian and New Zealand English Language. DME are classified according to the method of word formation, the type of semantic transfer and deliberate phonetic distortion. Selection of the analyzed units is made out of such lexicographical sources as online dictionary of colloquial vocabulary Urban Dictionary, online dictionary Oxford English Dictionary, Merriam-Webster Online: Dictionary and Thesaurus, ABBYY Lingvo, The Free Dictionary, Dictionary.com, electronic databases The Racial slur Database and Hatebase, lists of ethnonyms from online resources canadaka.com, fact-index.com and other sources of factual materials. The urgent character of the given article is caused by lack of scientific study of the ways of word formation of DME, particularly, the units of Canadian, Australian and New Zealand English. Separation of the criteria of their description and division into groups are considered to be important. The aim is to justify the linguistic phenomenon of DME through determining their structural and semantic characteristics in Canadian, Australian and New Zealand English. Achievement of the aim requires solving the following problems: 1 to identify the structural and semantic parameters of formation of DME; 2 to improve the structural and semantic classification of A.I. Hryshchenko for Canadian, Australian and New Zealand English.

  5. HYDROLOGIC AND FEATURE-BASED SURFACE ANALYSIS FOR TOOL MARK INVESTIGATION ON ARCHAEOLOGICAL FINDS

    Directory of Open Access Journals (Sweden)

    K. Kovács

    2012-07-01

    Full Text Available The improvement of detailed surface documentation methods provides unique tool mark-study opportunities in the field of archaeological researches. One of these data collection techniques is short-range laser scanning, which creates a digital copy of the object’s morphological characteristics from high-resolution datasets. The aim of our work was the accurate documentation of a Bronze Age sluice box from Mitterberg, Austria with a spatial resolution of 0.2 mm. Furthermore, the investigation of the entirely preserved tool marks on the surface of this archaeological find was also accomplished by these datasets. The methodology of this tool mark-study can be summarized in the following way: At first, a local hydrologic analysis has been applied to separate the various patterns of tools on the finds’ surface. As a result, the XYZ coordinates of the special points, which represent the edge lines of the sliding tool marks, were calculated by buffer operations in a GIS environment. During the second part of the workflow, these edge points were utilized to manually clip the triangle meshes of these patterns in reverse engineering software. Finally, circle features were generated and analysed to determine the different sections along these sliding tool marks. In conclusion, the movement of the hand tool could be reproduced by the spatial analysis of the created features, since the horizontal and vertical position of the defined circle centre points indicated the various phases of the movements. This research shows an exact workflow to determine the fine morphological structures on the surface of the archaeological find.

  6. Full-scale mark II CRT program facility description report

    International Nuclear Information System (INIS)

    Namatame, Ken; Kukita, Yutaka; Ito, Hideo; Yamamoto, Nobuo; Shiba, Masayoshi

    1980-03-01

    Started in fiscal year 1977, the Full-Scale Mark II CRT (Containment Response Test) Program is proceeding for the period of five years. The primary objective of the CRT Program is to provide a data base for evaluation of the pressure suppression pool hydrodynamic loads associated with a postulated loss-of-coolant accident in the BWR Mark II containment system. The test facility was designed and constructed from fiscal year 1977 to 1978, and completed in March 1979. It is 1/18 in volume and has a wetwell which is a full-scale replica of one 20 0 -sector of that of a reference Mark II. This report describes design concepts, dimensions and constructions of the test facility, as well as specifications, locations and installation schemes of the measuring equipments. Results of soil structure inspection, vacuum breaker test and shaker test of the containment shell are given in the appendices. (author)

  7. Better marking means cheaper pruning.

    Science.gov (United States)

    Kenneth R. Eversole

    1953-01-01

    Careful selection of trees to be pruned can make the difference between profit and loss on the pruning investment, especially in stands where no thinning is contemplated. Expert marking is required to make sure that the pruned trees will grow rapidly. The most important variable influencing the cost of clear wood produced by pruning is growth rate. For example, at 3...

  8. Obesity-related differences between women and men in brain structure and goal-directed behavior

    Directory of Open Access Journals (Sweden)

    Annette eHorstmann

    2011-06-01

    Full Text Available Gender differences in the regulation of body weight are well documented. Here, we assessed obesity-related influences of gender on brain structure as well as performance in the Iowa Gambling Task. This task requires evaluation of both immediate rewards and long-term outcomes and thus mirrors the trade-off between immediate reward from eating and the long-term effect of overeating on body weight. In women, but not in men, we show that the preference for salient immediate rewards in the face of negative long-term consequences is higher in obese than in lean subjects. In addition, we report structural differences in the left dorsal striatum (i.e. putamen and right dorsolateral prefrontal cortex for women only. Functionally, both regions are known to play complimentary roles in habitual and goal-directed control of behavior in motivational contexts. For women as well as men, gray matter volume correlates positively with measures of obesity in regions coding the value and saliency of food (i.e. nucleus accumbens, orbitofrontal cortex as well as in the hypothalamus (i.e. the brain's central homeostatic centre. These differences between lean and obese subjects in hedonic and homeostatic control systems may reflect a bias in eating behavior towards energy intake exceeding the actual homeostatic demand. Although we cannot infer from our results the etiology of the observed structural differences, our results resemble neural and behavioral differences well known from other forms of addiction, however, with marked differences between women and men. These findings are important for designing gender-appropriate treatments of obesity and possibly its recognition as a form of addiction.

  9. Mechanisms for Limiting Trade Mark Rights to Further Competition and Free Speech

    DEFF Research Database (Denmark)

    Ramsey, Lisa P; Schovsbo, Jens Hemmingsen

    2013-01-01

    This article evaluates the different mechanisms that nations use to limit trade mark rights to promote competition, free speech, and other public interests. It shows how EU and US trade mark laws seem to be converging towards a similar model which includes both (1) specific statutory defenses...... of these mechanisms for limiting trade mark rights to better protect the public interest in trade mark disputes. Finally, a proposal for reform is suggested. It consists of three parts: (1) domestic legislatures should revise their trade mark statutes to add more mandatory and specific limitations on trade mark...... to trade mark violations and (2) trade mark doctrines which give courts flexibility to permit unauthorized uses of marks that further the legitimate interests of the accused infringer and the public. Such a development should be welcomed and the article urges other nations to consider adopting one or both...

  10. Statistical methods for the forensic analysis of striated tool marks

    Energy Technology Data Exchange (ETDEWEB)

    Hoeksema, Amy Beth [Iowa State Univ., Ames, IA (United States)

    2013-01-01

    In forensics, fingerprints can be used to uniquely identify suspects in a crime. Similarly, a tool mark left at a crime scene can be used to identify the tool that was used. However, the current practice of identifying matching tool marks involves visual inspection of marks by forensic experts which can be a very subjective process. As a result, declared matches are often successfully challenged in court, so law enforcement agencies are particularly interested in encouraging research in more objective approaches. Our analysis is based on comparisons of profilometry data, essentially depth contours of a tool mark surface taken along a linear path. In current practice, for stronger support of a match or non-match, multiple marks are made in the lab under the same conditions by the suspect tool. We propose the use of a likelihood ratio test to analyze the difference between a sample of comparisons of lab tool marks to a field tool mark, against a sample of comparisons of two lab tool marks. Chumbley et al. (2010) point out that the angle of incidence between the tool and the marked surface can have a substantial impact on the tool mark and on the effectiveness of both manual and algorithmic matching procedures. To better address this problem, we describe how the analysis can be enhanced to model the effect of tool angle and allow for angle estimation for a tool mark left at a crime scene. With sufficient development, such methods may lead to more defensible forensic analyses.

  11. The Five Marks of the Mental

    Science.gov (United States)

    Pernu, Tuomas K.

    2017-01-01

    The mental realm seems different to the physical realm; the mental is thought to be dependent on, yet distinct from the physical. But how, exactly, are the two realms supposed to be different, and what, exactly, creates the seemingly insurmountable juxtaposition between the mental and the physical? This review identifies and discusses five marks of the mental, features that set characteristically mental phenomena apart from the characteristically physical phenomena. These five marks (intentionality, consciousness, free will, teleology, and normativity) are not presented as a set of features that define mentality. Rather, each of them is something we seem to associate with phenomena we consider mental, and each of them seems to be in tension with the physical view of reality in its own particular way. It is thus suggested how there is no single mind-body problem, but a set of distinct but interconnected problems. Each of these separate problems is analyzed, and their differences, similarities and connections are identified. This provides a useful basis for future theoretical work on psychology and philosophy of mind, that until now has too often suffered from unclarities, inadequacies, and conflations. PMID:28736537

  12. An NF-Y-dependent switch of positive and negative histone methyl marks on CCAAT promoters.

    Directory of Open Access Journals (Sweden)

    Giacomo Donati

    Full Text Available BACKGROUND: Histone tails have a plethora of different post-translational modifications, which are located differently in "open" and "closed" parts of genomes. H3K4me3/H3K79me2 and H4K20me3 are among the histone marks associated with the early establishment of active and inactive chromatin, respectively. One of the most widespread promoter elements is the CCAAT box, bound by the NF-Y trimer. Two of NF-Y subunits have an H2A-H2B-like structure. PRINCIPAL FINDINGS: We established the causal relationship between NF-Y binding and positioning of methyl marks, by ChIP analysis of mouse and human cells infected with a dominant negative NF-YA: a parallel decrease in NF-Y binding, H3K4me3, H3K79me2 and transcription was observed in promoters that are dependent upon NF-Y. On the contrary, changes in the levels of H3K9-14ac were more subtle. Components of the H3K4 methylating MLL complex are not recruited in the absence of NF-Y. As for repressed promoters, NF-Y removal leads to a decrease in the H4K20me3 mark and deposition of H3K4me3. CONCLUSIONS: Two relevant findings are reported: (i NF-Y gains access to its genomic locations independently from the presence of methyl histone marks, either positive or negative; (ii NF-Y binding has profound positive or negative consequences on the deposition of histone methyl marks. Therefore NF-Y is a fundamental switch at the heart of decision between gene activation and repression in CCAAT regulated genes.

  13. Beyond the Sensible World: A Discussion of Mark Zuss' The Practice of Theoretical Curiosity

    Science.gov (United States)

    Fellner, Gene; Pitts, Wesley; Zuss, Mark

    2012-01-01

    In this article, Gene Fellner reviews Mark Zuss's recently published "The practice of theoretical curiosity" (2012) and provides a synopsis of the book's structure. These two sections are followed by a metalogue in which Mark Zuss, Welsey Pitts, and Fellner discuss curiosity and the conundrum of establishing limits beyond which curiosity should…

  14. Experimental investigation of tread wear and particle emission from tyres with different treadwear marking

    Science.gov (United States)

    Grigoratos, Theodoros; Gustafsson, Mats; Eriksson, Olle; Martini, Giorgio

    2018-06-01

    The Treadwear Rating (TWR) provided on the sidewall of the tyre is a marking intended to inform the customer about the expected durability of the tyre. The current study explores whether there is a correlation between the TWR and tyres' tread mass loss. Furthermore, it explores the possible correlation between the TWR and tyre wear dust emitted in the form of PM10 and PM2.5. For that reason, two tyres of the same brand (B) but with different TWR and three tyres of different brands (C and D with the same TWR as one of the B tyres and A with a lower TWR) were tested at a constant speed of 70 km/h by means of the Swedish National Road and Transport Research Institute (VTI) road simulator. Tyres of the same TWR but of different brands showed different behaviour in terms of material loss, PM, and PN emissions under the selected testing conditions. This means that it is not feasible to categorize tyres of different brands in terms of their emissions based on their TWR. The test performed on the two tyres of the same brand but with different TWR showed instead a substantial (not statistically significant) difference in both total wear and PM10 emissions. The tyre with the higher TWR (B2) showed less wear and PM10 emissions compared to the B1 tyre having a lower TWR. Since only two tyres of the same brand and with different TWR were tested, this result cannot be generalized and more tests are necessary to confirm the relation within the same brand. In general, the tyre tread mass loss showed no obvious statistical relation to PM10, PM2.5 or PN concentration. In all cases approximately 50% (by mass) of emitted PM10 fall within the size range of fine particles, while PN size distribution is dominated by nanoparticles most often peaking at 20-30 nm.

  15. Marking behavior of the giant anteater Myrmecophaga tridactyla (Mammalia: Myrmecophagidae in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Fernanda G. Braga

    2010-02-01

    Full Text Available This research presents novel data on tree marking by the giant anteater, a large Neotropical mammal threatened in the state of Paraná and other areas of Brazil, and nearly threatened worldwide. Field work was carried out in the municipality of Jaguariaíva, Paraná (Southern Brazil with the goal of evaluating the pine marking behavior of the giant anteater and ascertaining whether wildfires interfere with it. Anteater marks were searched for on the trunks of pine trees in stands as well as pine trees dispersed throughout the landscape. For each pine tree, the following features were recorded: height, diameter breast height (DBH, height of first branch, presence/absence of scratch marks, geographical location, substrate, and matrix. The total number of scratches, scratch directions, scratch length, and height of top mark were also recorded. The scratches were defined as horizontal or vertical. Tree scratching was directly observed in three instances. Ninety-one trees were measured in the study area. The differences between marked and non-marked pines were significant for DBH and height of first branch. All scratches were found on pines dispersed throughout the landscape. Trees with horizontal and vertical marks were significantly different in terms of DBH, first branch height, and top mark height. After a wildfire that affected part of the study area, 54% of the previously marked trees were marked anew. We suggest that the marking behavior is used for communication between conspecifics with overlapping home ranges, possibly during the mating season. Additionally, we advance the hypothesis that pine marking behavior becomes more frequent with increased population stress due to anthropic interference.

  16. Survival and its predictors from age 75 to 85 in men and women belonging to cohorts with marked survival differences to age 75

    DEFF Research Database (Denmark)

    Heikkinen, E; Kauppinen, M; Schroll, M

    2016-01-01

    focusing on different domains of health, functional capacity, and physical and social activities. RESULTS: The proportion of survivors to age 75 was markedly smaller among the Finnish men and women than Danish or Swedish subjects. In the local population no marked differences in survival from age 75 to 85...... among three local Nordic populations using survival data on national cohorts as background information. METHODS: The data were derived from national registers and from samples of 75-year old living in Denmark, Sweden, and Finland. The subjects were invited to take part in interviews and examinations...... were observed between the groups of men, while women survived longer than men and longer in Göteborg than in Glostrup or Jyväskylä. Univariate models revealed 12 predictors of survival. In the multivariate models, the significant predictors among men related to physical fitness, whereas among women...

  17. Leukocyte subtype counts and its association with vascular structure and function in adults with intermediate cardiovascular risk. MARK study.

    Directory of Open Access Journals (Sweden)

    Leticia Gomez-Sanchez

    Full Text Available We investigated the relationship between leukocyte subtype counts and vascular structure and function based on carotid intima-media thickness, pulse wave velocity, central augmentation index and cardio-ankle vascular index by gender in intermediate cardiovascular risk patients.This study analyzed 500 subjects who were included in the MARK study, aged 35 to 74 years (mean: 60.3±8.4, 45.6% women.Brachial ankle Pulse Wave Velocity (ba-PWV estimate by equation, Cardio-AnkleVascular Index (CAVI using the VaSera device and Carotid ultrasound was used to measure carotid Intima Media Thickness (IMT. The Mobil-O-Graph was used to measure the Central Augmentation Index (CAIx.Total leukocyte, neutrophil and monocyte counts were positively correlated with IMT (p < 0.01 in men. Monocyte count was positively correlated with CAIx in women (p < 0.01. In a multiple linear regression analysis, the IMT mean maintained a positive association with the neutrophil count (β = 1.500, p = 0.007 in men. CAIx maintained a positive association with the monocyte count (β = 2.445, p = 0.022 in women.The results of this study suggest that the relationship between subtype circulating leukocyte counts and vascular structure and function, although small, may be different by gender. In men, the neutrophil count was positively correlated with IMT and in women, the monocyte count with CAIx, in a large sample of intermediate-risk patients. These association were maintained after adjusting for age and other confounders.ClinicalTrials.gov NCT01428934.

  18. Factors influencing survival and mark retention in postmetamorphic boreal chorus frogs

    Science.gov (United States)

    Swanson, Jennifer E; Bailey, Larissa L.; Muths, Erin L.; Funk, W. Chris

    2013-01-01

    The ability to track individual animals is crucial in many field studies and often requires applying marks to captured individuals. Toe clipping has historically been a standard marking method for wild amphibian populations, but more recent marking methods include visual implant elastomer and photo identification. Unfortunately, few studies have investigated the influence and effectiveness of marking methods for recently metamorphosed individuals and as a result little is known about this life-history phase for most amphibians. Our focus was to explore survival probabilities, mark retention, and mark migration in postmetamorphic Boreal Chorus Frogs (Psuedacris maculata) in a laboratory setting. One hundred forty-seven individuals were assigned randomly to two treatment groups or a control group. Frogs in the first treatment group were marked with visual implant elastomer, while frogs in the second treatment group were toe clipped. Growth and mortality were recorded for one year and resulting data were analyzed using known-fate models in Program MARK. Model selection results suggested that survival probabilities of frogs varied with time and showed some variation among marking treatments. We found that frogs with multiple toes clipped on the same foot had lower survival probabilities than individuals in other treatments, but individuals can be marked by clipping a single toe on two different feet without any mark loss or negative survival effects. Individuals treated with visual implant elastomer had a mark migration rate of 4% and mark loss rate of 6%, and also showed very little negative survival impacts relative to control individuals.

  19. Absolute and relative dose measurements with Gafchromic trade mark sign EBT film for high energy electron beams with different doses per pulse

    International Nuclear Information System (INIS)

    Fiandra, Christian; Ragona, Riccardo; Ricardi, Umberto; Anglesio, Silvia; Giglioli, Francesca Romana

    2008-01-01

    The authors have evaluated the accuracy, in absolute and relative dose measurements, of the Gafchromic trade mark sign EBT film in pulsed high-energy electron beams. Typically, the electron beams used in radiotherapy have a dose-per-pulse value of less than 0.1 mGy/pulse. However, very high dose-per-pulse electron beams are employed in certain linear accelerators dedicated to intraoperatory radiation therapy (IORT). In this study, the absorbed dose measurements with Gafchromic trade mark sign EBT in both low (less than 0.3 mGy per pulse) and high (30 and 70 mGy per pulse) dose-per-pulse electron beams were compared with ferrous sulfate chemical Fricke dosimetry (operated by the Italian Primary Standard Dosimetry Laboratory), a method independent of the dose per pulse. A summary of Gafchromic trade mark sign EBT in relative and absolute beam output determination is reported. This study demonstrates the independence of Gafchromic trade mark sign EBT absorption as a function of dose per pulse at different dose levels. A good agreement (within 3%) was found with Fricke dosimeters for plane-base IORT applicators. Comparison with a diode detector is presented for relative dose measurements, showing acceptable agreement both in the steep dose falloff zone and in the homogeneous dose region. This work also provides experimental values for recombination correction factor (K sat ) of a Roos (plane parallel) ionization chamber calculated on the basis of theoretical models for charge recombination.

  20. Survival of radio-marked mallard ducklings in northeastern California

    Science.gov (United States)

    Mauser, D.M.; Jarvis, R.L.; Gilmer, D.S.

    1994-01-01

    Estimates of duckling survival are necessary to accurately assess recruitment of mallards (Anas platyrhynchos), yet few reliable estimates exist. During 1988-90, we estimated survival rates for 127 radio-marked mallard ducklings from 64 broods on Lower Klamath National Wildlife Refuge, California. In 1988, we restricted the survival estimate to the first 10 days post-hatch (S = 0.18, SE = 0.07). Survival from hatching to 50 days was 0.37 (SE = 0.09) in 1989 and 0.34 (SE = 0.07) in 1990. Total brood loss differed among years (P < 0.05); 81.2% in 1988 (n = 16), 36.8% in 1989 (n = 19), and 37.5% in 1990 (n = 24). Ninety-three percent of mortality occurred during the first 10 days of life. We detected no differences in the proportion of radio-marked ducklings fledged from early-hatched versus late-hatched nests (P = 0.74). During 1989-90, 16 females appeared to lose their entire brood; however, 3 radio-marked ducklings from 2 of these broods were fledged by other brood hens. Of 29 radio-marked ducklings that reached 44 days of life, 6 (20.7%) joined other broods. Habitat enhancement is the key to improving duckling survival because the large number of predator species that consume ducklings makes predator control difficult.

  1. 46 CFR 185.602 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part 67...

  2. Negative Marking and the Student Physician–-A Descriptive Study of Nigerian Medical Schools

    Directory of Open Access Journals (Sweden)

    Ikenna Kingsley Ndu

    2016-01-01

    Full Text Available Background There is considerable debate about the two most commonly used scoring methods, namely, the formula scoring (popularly referred to as negative marking method in our environment and number right scoring methods. Although the negative marking scoring system attempts to discourage students from guessing in order to increase test reliability and validity, there is the view that it is an excessive and unfair penalty that also increases anxiety. Feedback from students is part of the education process; thus, this study assessed the perception of medical students about negative marking method for multiple choice question (MCQ examination formats and also the effect of gender and risk-taking behavior on scores obtained with this assessment method. Methods This was a prospective multicenter survey carried out among fifth year medical students in Enugu State University and the University of Nigeria. A structured questionnaire was administered to 175 medical students from the two schools, while a class test was administered to medical students from Enugu State University. Qualitative statistical methods including frequencies, percentages, and chi square were used to analyze categorical variables. Quantitative statistics using analysis of variance was used to analyze continuous variables. Results Inquiry into assessment format revealed that most of the respondents preferred MCQs (65.9%. One hundred and thirty students (74.3% had an unfavorable perception of negative marking. Thirty-nine students (22.3% agreed that negative marking reduces the tendency to guess and increases the validity of MCQs examination format in testing knowledge content of a subject compared to 108 (61.3% who disagreed with this assertion (χ 2 = 23.0, df = 1, P = 0.000. The median score of the students who were not graded with negative marking was significantly higher than the score of the students graded with negative marking ( P = 0.001. There was no statistically

  3. Mark Kostabi soovib muuta inimesi õnnelikumaks / Kalev Mark Kostabi

    Index Scriptorium Estoniae

    Kostabi, Kalev Mark, 1960-

    2008-01-01

    Kalev Mark Kostabi oma sisekujunduslikest eelistustest, ameeriklaste ja itaallaste kodude sisekujunduse erinevustest, kunstist kui ruumikujunduse ühest osast, oma New Yorgi ja Rooma korterite kujundusest

  4. Marking system for scintillation camera and computer, and its clinical application

    Energy Technology Data Exchange (ETDEWEB)

    Narabayashi, I [Kinki Univ., Higashi-Osaka, Osaka (Japan); Ito, K; Yoshida, S; Yamaguchi, H; Kahata, S

    1976-03-01

    In routine clinical studies, we have noted that in some cases anatomical marks have been transferred to scintigrams through the scintillation camera. It was thought that radioactive point sources could be used as anatomical marks. However, this method resulted in an ill-defined area of brightness. The marking equipment for the scintillation camera used in this study consisted of a linear potentiometer and a sine-cosine potentiometer. We designed a marking method for a data processing system using the marking equipment for a scintillation camera. The data processing system of a scintillation camera is composed of EDR-4000 (8K core memories), MT recorder, CRT display, and graphic display unit and it is connected by on-line to the scintillation camera. A marking program was made in order to record marking addresses on a processed image. Using this soft program and graphpen of the graphic display unit, we transferred marks to processed image by points and lines. Subtraction scintigraphy using /sup 198/Au-colloid and /sup 75/Se-selenomethionine was performed on cases of pancreas carcinoma. After marking addresses were recorded on a processed image by this marking method, the signals from the scintillation camera were fed into the input controller. Then these signals with marking points were transferred from the computer to the MT recorder. Subtraction scintigraphy by this system made it possible to examine each picture with /sup 198/Au-colloid of /sup 75/Se-selenomethionine at different times.

  5. 27 CFR 28.193 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.193... Drawback Filing of Notice and Removal § 28.193 Export marks. In addition to the marks and brands required... chapter, the exporter shall mark the word “Export” on the Government side of each case or Government head...

  6. 27 CFR 28.103 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.103... Manufacturing Bonded Warehouse § 28.103 Export marks. (a) General. In addition to the marks and brands required... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

  7. 27 CFR 28.144 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.144... § 28.144 Export marks. (a) General Requirement. In addition to the marks and brands required to be... brewer shall mark the word “Export” on each container or case of beer, or the words “Beer concentrate for...

  8. 27 CFR 28.154 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.154..., for Exportation or Transfer to a Foreign-Trade Zone § 28.154 Export marks. In addition to the marks... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

  9. 1L Mark-IV Target Design Review

    Energy Technology Data Exchange (ETDEWEB)

    Koehler, Paul E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-16

    This presentation includes General Design Considerations; Current (Mark-III) Lower Tier; Mark-III Upper Tier; Performance Metrics; General Improvements for Material Science; General Improvements for Nuclear Science; Improving FOM for Nuclear Science; General Design Considerations Summary; Design Optimization Studies; Expected Mark-IV Performance: Material Science; Expected Mark-IV Performance: Nuclear Science (Disk); Mark IV Enables Much Wider Range of Nuclear-Science FOM Gains than Mark III; Mark-IV Performance Summary; Rod or Disk? Center or Real FOV?; and Project Cost and Schedule.

  10. Trail marking by caterpillars of the silverspot butterfly Dione juno huascuma.

    Science.gov (United States)

    Pescador-Rubio, Alfonso; Stanford-Camargo, Sergio G; Páez-Gerardo, Luis E; Ramírez-Reyes, Alberto J; Ibarra-Jiménez, René A; Fitzgerald, Terrence D

    2011-01-01

    A pheromone is implicated in the trail marking behavior of caterpillars of the nymphalid silverspot butterfly, Dione juno huascuma (Reakirt) (Lepidoptera: Heliconiinae) that feed gregariously on Passiflora (Malpighiales: Passifloraceae) vines in Mexico. Although they mark pathways leading from one feeding site to another with silk, this study shows that the silk was neither adequate nor necessary to elicit trail following behavior. Caterpillars marked trails with a long-lived pheromone that was deposited when they brushed the ventral surfaces of the tips of their abdomens along branch pathways. The caterpillars distinguished between pathways deposited by different numbers of siblings and between trails of different ages. Caterpillars also preferentially followed the trails of conspecifics over those of another nymphalid, Nymphalis antiopa L., the mourning cloak butterfly.

  11. An assessment of structural response of condensation pool columns in a BWR/MARK II containment to loads resulting from steam explosions

    International Nuclear Information System (INIS)

    Frid, W.

    1989-01-01

    The objective is to estimate the amount of molten core debris participating in a postulated propagating large-scale steam explosion that could threaten the integrity of the condensation pool columns in a BWR/MARK II containment. This objective was achieved by examination of the structural response of the columns to shock wave loadings and comparison, on the shock wave energy basis, of a propagating steam explosion to a detonation of TNT. In this connection the fraction of the steam explosion energy which appears in the form of a pressure shock wave was estimated. (orig.)

  12. Changing Context of Trade Mark Protection in India: A Review of the Trade Marks Act, 1999

    OpenAIRE

    Pathak, Akhileshwar

    2004-01-01

    With liberalisation and globalisation of the Indian economy, it has become possible for anyone to get into production and services in most of the sectors. This has led to rampant misuse and appropriation of trade marks. In an insulated economy, with monopoly markets, law protecting trade marks had a limited role. In the changed context, however, trade mark law will be a field of much interest for academics and practitioners. Towards this, the paper explores the formation of trade mark law in ...

  13. Fingerprint Analysis with Marked Point Processes

    DEFF Research Database (Denmark)

    Forbes, Peter G. M.; Lauritzen, Steffen; Møller, Jesper

    We present a framework for fingerprint matching based on marked point process models. An efficient Monte Carlo algorithm is developed to calculate the marginal likelihood ratio for the hypothesis that two observed prints originate from the same finger against the hypothesis that they originate from...... different fingers. Our model achieves good performance on an NIST-FBI fingerprint database of 258 matched fingerprint pairs....

  14. Different microprocessor controlled devices for ITU TRIGA Mark II reactor

    International Nuclear Information System (INIS)

    Can, B.; Omuz, S.; Uzun, S.; Apan, H.

    1990-01-01

    In this paper the design of a period meter and multichannel thermometer, which are controlled by a microprocessor, in order to be used at ITU TRIGA Mark-II Reactor is presented. The system works as a simple microcomputer, which includes a CPU, a EPROM, a RAM, a CTC, a PIO, a PIA a keyboard and displays, using the assembly language. The period meter can work either with pulse signal or with analog signal depending on demand of the user. The period is calculated by software and its range is -99,9 sec, to +2.1 sec. When the period drops +3 sec, the system gives alarm illuminating a LED. The multichannel thermometer has eight temperature channels. Temperature channels can manually or automatically be selected. The channel selection time can be adjusted. The thermometer gives alarm illuminating a LED, when the temperature rises to 600 C. Temperature data is stored in the RAM and is shown on a display. This system provides us to use four spare thermocouples in the reactor. (orig.)

  15. Court presentation of bite mark evidence.

    Science.gov (United States)

    Drinnan, A J; Melton, M J

    1985-12-01

    The uniqueness of an individual's bite mark is generally accepted. The use of bite mark analysis to identify or exclude those suspected of crimes is now a well established activity in forensic dentistry. Although the techniques for evaluating bite mark evidence are extremely sophisticated, it is important that the courtroom presentation of such evidence should be as simple as possible and be directed towards those who must judge it. Dentists likely to be involved in the courtroom presentation of bite mark evidence should: be certain that their local law enforcement personnel are frequently updated on the techniques to be used for producing the optimum evidence needed to evaluate bite marks; become acquainted with the current techniques of evaluating bite mark evidence and understand their difficulties and pitfalls; meet with the lawyers (prosecution or defence) before a courtroom appearance, briefing them on the significance of the particular findings; prepare clear and easily understandable visual aids to present to the court the techniques used in the analysis and the bases for the conclusion reached; and offer conclusions derived from the bite mark investigation.

  16. Effect of artificial sunlight on the retention of external calcein marks on lake trout

    Science.gov (United States)

    Honeyfield, D.C.; Kehler, T.; Fletcher, J.W.; Mohler, J.W.

    2008-01-01

    When choosing a fish marking technique to address fishery related questions, it is important to consider factors that affect mark retention. Calcein, a chemical marking agent, is under investigation for potential use on fish. Two laboratory trials were conducted with calcein-marked lake trout Salvelinus namaycush to determine the effect of artificial sunlight on calcein mark intensity. In trial 1, fish exposed to 18,000 lx for 7 d lost 90% or more of the calcein mark intensity (relative to the colorimetric key, mg/L) on the head, body, ventral region, and pectoral fins relative to mark intensity in fish that were maintained in darkness. In trial 2, light intensity was reduced 2.5-3.0-fold. After 7 d of light exposure, calcein mark intensity on the head was reduced by 40-45% relative to mark intensity in fish that were held in darkness; by day 14, calcein mark intensity on the head was reduced by 55-60% relative to that of dark-treated fish. No further decline was observed in light-exposed fish, and head mark intensity values did not differ among days 14, 21, and 28 for this treatment group. Of the four areas evaluated, the head and pectoral fin were more easily read using a colorimetric key than the lateral or ventral regions of the fish. The concentration of calcein spotted on filter paper to devise the colorimetric key ranged from 1 to 100 mg/L. A difference of approximately 7 mg/L in apparent calcein mark intensity means for the head region could be detected using the colorimetric key. These trials showed that calcein mark intensity on lake trout declined when fish were exposed to artificial sunlight, and the use of a colorimetric key improved the objectivity of calcein mark intensity assessment.

  17. Nuclear particle track-etched anti-bogus mark

    International Nuclear Information System (INIS)

    He Xiangming; Yan Yushun; Zhang Quanrong

    2003-01-01

    Nuclear particle track-etched anti-bogus mark is a new type of forgery-proof product after engraving gravure printing, thermocolour, fluorescence, laser hologram and metal concealed anti-bogus mark. The mark is manufactured by intricate high technology and the state strictly controlled sensitive nuclear facilities to ensure the mark not to be copied. The pattern of the mark is specially characterized by permeability of liquid to be discriminated from forgery. The genuine mark can be distinguished from sham one by transparent liquid (e.g. water), colorful pen and chemical reagent. The mark has passed the official examination of health safety. It is no danger of nuclear irradiation. (author)

  18. Comparison of the reference mark azimuth determination methods

    Directory of Open Access Journals (Sweden)

    Danijel Šugar

    2013-03-01

    Full Text Available The knowledge of the azimuth of the reference mark is of crucial importance in the determination of the declination which is defined as the ellipsoidal (geodetic azimuth of the geomagnetic meridian. The accuracy of the azimuth determination has direct impact on the accuracy of the declination. The orientation of the Declination-Inclination Magnetometer is usually carried out by sighting the reference mark in two telescope faces in order to improve the reliability of the observations and eliminate some instrumental errors. In this paper, different coordinate as well as azimuth determination methods using GNSS (Global Navigation Satellite System observation techniques within VPPS (High-Precision Positioning Service and GPPS (Geodetic-Precision Positioning Service services of the CROPOS (CROatian POsitioning System system were explained. The azimuth determination by the observation of the Polaris was exposed and it was subsequently compared with the observation of the Sun using hour-angle and zenith-distance method. The procedure of the calculation of the geodetic azimuth from the astronomic azimuth was explained. The azimuth results obtained by different methods were compared and the recommendations on the minimal distance between repeat station and azimuth mark were given. The results shown in this paper were based on the observations taken on the POKU_SV repeat station.

  19. Influences of Phonological Context on Tense Marking in Spanish–English Dual Language Learners

    Science.gov (United States)

    Barlow, Jessica A.; Potapova, Irina; Pruitt-Lord, Sonja

    2017-01-01

    Purpose The emergence of tense-morpheme marking during language acquisition is highly variable, which confounds the use of tense marking as a diagnostic indicator of language impairment in linguistically diverse populations. In this study, we seek to better understand tense-marking patterns in young bilingual children by comparing phonological influences on marking of 2 word-final tense morphemes. Method In spontaneous connected speech samples from 10 Spanish–English dual language learners aged 56–66 months (M = 61.7, SD = 3.4), we examined marking rates of past tense -ed and third person singular -s morphemes in different environments, using multiple measures of phonological context. Results Both morphemes were found to exhibit notably contrastive marking patterns in some contexts. Each was most sensitive to a different combination of phonological influences in the verb stem and the following word. Conclusions These findings extend existing evidence from monolingual speakers for the influence of word-final phonological context on morpheme production to a bilingual population. Further, novel findings not yet attested in previous research support an expanded consideration of phonological context in clinical decision making and future research related to word-final morphology. PMID:28750415

  20. 46 CFR 160.176-23 - Marking.

    Science.gov (United States)

    2010-10-01

    ... of the vessel. (2) The type of vessel. (3) Specific purpose or limitation approved by the Coast Guard...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-23 Marking. (a) General. Each inflatable lifejacket must be marked with the information required by this section. Each marking must be...

  1. On-road Bicycle Pavement Markings

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — A mile by mile breakdown of the on-street bicycle pavement markings installed within the City of Pittsburgh. These include bike lanes, shared lane markings...

  2. Marks of Metal Copenhell

    DEFF Research Database (Denmark)

    2015-01-01

    Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet.......Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet....

  3. Circulatory Markings at Double-Lane Traffic Roundabout.

    NARCIS (Netherlands)

    Bie, Jing; Lo, Hong K.; Wong, S.C.

    2008-01-01

    This paper compares two types of circulatory markings at a double-lane traffic roundabout: the concentric marking scheme and the Alberta marking scheme. The effects of these two marking schemes on drivers' lane choice behavior, delay, and safety, are compared based on data collected from before and

  4. 7 CFR 160.32 - Marking containers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Marking containers. 160.32 Section 160.32 Agriculture... STANDARDS FOR NAVAL STORES Analysis, Inspection, and Grading on Request § 160.32 Marking containers. The interested person shall provide any labor necessary for marking the containers, after the contents have been...

  5. 46 CFR 122.602 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Hull markings. 122.602 Section 122.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150....602 Hull markings. (a) Each vessel must be marked as required by part 67, subpart I, of this chapter...

  6. Principles of developing the bench mark net for radioecological monitoring in the territory of Byelorussia

    International Nuclear Information System (INIS)

    Doroshkevich, M.N.

    1991-01-01

    The principles of developing the radioecological monitoring bench mark net proposed include the regularity pattern of reference point setting, the bench mark net hierarchy, accounting for a land-tenure structure and the landscape and geochemical conditions of the radionuclide migration as well as a passport system and informational adequacy. The expression has been obtained for determining the location of sampling points

  7. Stretch Marks

    Science.gov (United States)

    ... completely without the help of a dermatologist or plastic surgeon. These doctors may use one of many types of treatments — from actual surgery to techniques like microdermabrasion and laser treatment — to reduce the appearance of stretch marks. These techniques are ...

  8. 27 CFR 28.123 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.123..., or Transportation to a Manufacturing Bonded Warehouse § 28.123 Export marks. (a) General. In addition... filled under the provisions of part 24 of this chapter, the proprietor shall mark the word “Export” on...

  9. Identification of the Rice Wines with Different Marked Ages by Electronic Nose Coupled with Smartphone and Cloud Storage Platform.

    Science.gov (United States)

    Wei, Zhebo; Xiao, Xize; Wang, Jun; Wang, Hui

    2017-10-31

    In this study, a portable electronic nose (E-nose) was self-developed to identify rice wines with different marked ages-all the operations of the E-nose were controlled by a special Smartphone Application. The sensor array of the E-nose was comprised of 12 MOS sensors and the obtained response values were transmitted to the Smartphone thorough a wireless communication module. Then, Aliyun worked as a cloud storage platform for the storage of responses and identification models. The measurement of the E-nose was composed of the taste information obtained phase (TIOP) and the aftertaste information obtained phase (AIOP). The area feature data obtained from the TIOP and the feature data obtained from the TIOP-AIOP were applied to identify rice wines by using pattern recognition methods. Principal component analysis (PCA), locally linear embedding (LLE) and linear discriminant analysis (LDA) were applied for the classification of those wine samples. LDA based on the area feature data obtained from the TIOP-AIOP proved a powerful tool and showed the best classification results. Partial least-squares regression (PLSR) and support vector machine (SVM) were applied for the predictions of marked ages and SVM (R² = 0.9942) worked much better than PLSR.

  10. Identification of the Rice Wines with Different Marked Ages by Electronic Nose Coupled with Smartphone and Cloud Storage Platform

    Directory of Open Access Journals (Sweden)

    Zhebo Wei

    2017-10-01

    Full Text Available In this study, a portable electronic nose (E-nose was self-developed to identify rice wines with different marked ages—all the operations of the E-nose were controlled by a special Smartphone Application. The sensor array of the E-nose was comprised of 12 MOS sensors and the obtained response values were transmitted to the Smartphone thorough a wireless communication module. Then, Aliyun worked as a cloud storage platform for the storage of responses and identification models. The measurement of the E-nose was composed of the taste information obtained phase (TIOP and the aftertaste information obtained phase (AIOP. The area feature data obtained from the TIOP and the feature data obtained from the TIOP-AIOP were applied to identify rice wines by using pattern recognition methods. Principal component analysis (PCA, locally linear embedding (LLE and linear discriminant analysis (LDA were applied for the classification of those wine samples. LDA based on the area feature data obtained from the TIOP-AIOP proved a powerful tool and showed the best classification results. Partial least-squares regression (PLSR and support vector machine (SVM were applied for the predictions of marked ages and SVM (R2 = 0.9942 worked much better than PLSR.

  11. [The scent marking of territory of gerbils: a comparative analysis exemplified by 4 species of the genus Meriones].

    Science.gov (United States)

    Gromov, V S

    1997-01-01

    Sex-age and seasonal variability of the ventral glands and different stereotypes of scent marking behaviour in four Meriones species (M. unguiculatus, M. meridianus, M. libycus, M. tamariscinus) have been studied in nature and under semi-natural conditions. Two major ways of olfactory marking are considered: by secretion of the ventral glands and by "signal heaps" with urine and feces. Intraspecific and inter-species variability of marking activity is investigated. The ventral glands start to function at the period of preparation of a generative system to reproduction. The peak of secretary activity of gland and maximum of two types of marking activity is observed in spring and early summer, i.e. the period of active reproduction. The maximum of two types of the marking activity is observed during this period. In M. tamariscinus and M. meridianus the marking by the ventral gland is prevailing mode of the territory scent marking, while Mongolian gerbils (M. unguiculatus) prefer to use "signal heaps" Libyan gerbils (M. libycus) in this relation take an intermediate position. At the non-productive period a level of marking activity is on 10-20 times lower than at the reproductive season. Besides hormonal, social factors were also important for regulation of marking activity. By influence of these factors the differences in the level of marking activity in high-rank and low-rank individuals and differences in patterns of a spatial distribution of scent marks in individuals of different hierarchical rank is explained. Functional significance of various ways of territory scent marking is discussed.

  12. 27 CFR 28.223 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.223... Export marks. In addition to the marks and brands required to be placed on kegs, barrels, cases, crates... “Export” on each container or case before removal for export, for use on vessels or aircraft, or for...

  13. Learning to mark: a qualitative study of the experiences and concerns of medical markers

    Directory of Open Access Journals (Sweden)

    Cannings-John Rebecca

    2006-04-01

    Full Text Available Abstract Background Although there is published research on the methods markers use in marking various types of assessment, there is relatively little information on the processes markers use in approaching a marking exercise. This qualitative paper describes the preparation and experiences of general practice (GP teachers who undertake marking a written assessment in an undergraduate medical course. Methods Semi-structured interviews were conducted with seven of the 16 GP tutors on an undergraduate course. The purposive sample comprised two new markers, two who had marked for a couple of years and three experienced markers. Each respondent was interviewed twice, once following a formative assessment of a written case study, and again after a summative assessment. All interviews were audio-taped and analysed for emerging themes. A respondent validation exercise was conducted with all 16 GP tutors. Results Markers had internal concerns about their ability to mark fairly and made considerable efforts to calibrate their marking. They needed guidance and coaching when marking for the first time and adopted a variety of marking styles, reaching a decision through a number of routes. Dealing with pass/fail borderline scripts and the consequences of the mark on the student were particular concerns. Even experienced markers felt the need to calibrate their marks both internally and externally Conclusion Previous experience of marking appears to improve markers' confidence and is a factor in determining the role which markers adopt. Confidence can be improved by giving clear instructions, along with examples of marking. The authors propose that one method of providing this support and coaching could be by a process of peer review of a selection of papers prior to the main marking. New markers in particular would benefit from further guidance, however they are influenced by others early on in their marking career and course organisers should be mindful of

  14. Study of gunshot residues from Sintox® ammunition containing marking substances

    Directory of Open Access Journals (Sweden)

    Júlia Polovková

    2015-12-01

    Full Text Available Two types of factory marked Sintox® ammunition were investigated from the composition of gunshot residue particles (GSR and occurrence of marking substance points of view. The experiments were carried out with two cartridges of caliber 9 mm Luger (9 × 19 Parabellum of two producers (Ruag Ammotec, Switzerland and Men, Germany. The first cartridge (type Action 4, Ruag Ammotec contains gadolinium as a marking element, while the other cartridge (type PEP II, Men is marked with gallium in gunpowder. Scanning electron microscopy equipped with EDAX analyzer (SEM/EDX was used to detect and analyze the GSR particles in samples collected from the cartridges, barrels and shooter’s hands. Besides those, particles from the hit clothes placed at different shooting distances were collected and analyzed. The spreading of GSR cloud from the gun was observed using the high-speed camera. Results obtained clearly revealed that the way of ammunition production/construction and type of marking of ammunition can significantly influence the presence and detection reliability of marking elements in GSR. The detectability is affected also by the shooting distance.

  15. 46 CFR 78.50-5 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Hull markings. 78.50-5 Section 78.50-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS OPERATIONS Markings on Vessels § 78.50-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this chapter. [CGD 72...

  16. 46 CFR 196.40-5 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 196.40-5 Section 196.40-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS OPERATIONS Markings on Vessels § 196.40-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this chapter...

  17. 46 CFR 97.40-5 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Hull markings. 97.40-5 Section 97.40-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS OPERATIONS Markings on Vessels § 97.40-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this...

  18. Automatic Extraction of Road Markings from Mobile Laser Scanning Data

    Science.gov (United States)

    Ma, H.; Pei, Z.; Wei, Z.; Zhong, R.

    2017-09-01

    Road markings as critical feature in high-defination maps, which are Advanced Driver Assistance System (ADAS) and self-driving technology required, have important functions in providing guidance and information to moving cars. Mobile laser scanning (MLS) system is an effective way to obtain the 3D information of the road surface, including road markings, at highway speeds and at less than traditional survey costs. This paper presents a novel method to automatically extract road markings from MLS point clouds. Ground points are first filtered from raw input point clouds using neighborhood elevation consistency method. The basic assumption of the method is that the road surface is smooth. Points with small elevation-difference between neighborhood are considered to be ground points. Then ground points are partitioned into a set of profiles according to trajectory data. The intensity histogram of points in each profile is generated to find intensity jumps in certain threshold which inversely to laser distance. The separated points are used as seed points to region grow based on intensity so as to obtain road mark of integrity. We use the point cloud template-matching method to refine the road marking candidates via removing the noise clusters with low correlation coefficient. During experiment with a MLS point set of about 2 kilometres in a city center, our method provides a promising solution to the road markings extraction from MLS data.

  19. Metallographic examinations of the wear-marks on fuel pins of the KNK II/2 fuel assembly NY-308

    International Nuclear Information System (INIS)

    Patzer, G.

    1987-12-01

    On the fuel pins and pin spacers of the fuel assembly NY-308 of the second core of KNK II pronounced wear marks had been found in the area of the contact points. In order to determine the exact form of the marks, metallographic investigations were performed on two test pieces of fuel pins in the Hot Cells of the KfK Karlsruhe. It was found that the wear marks did show the already observed stratified structure. Next to the unchanged cladding area there is a peripheral zone with modified grain structure, followed by a layer of moved material and finally there is a flake-like zone of accumulated cladding material at the lower end of the wear marks. Longitudinal cuts do not show grain deformations, which could indicate axial friction forces between pin and spacer. The wear marks are rapidly dropping to their maximum depth at the ends and the depth shows a relatively uniform pattern between both. The findings are confirming the picture, that a stirring movement of the fuel pins took place, which caused adhesive wear [de

  20. Genotoxic effect of radio marked lymphocytes using Tc-99m complexes

    International Nuclear Information System (INIS)

    Pedraza L, M.; Ferro F, G.; Mendiola C, M.T.; Morales R, P.

    1997-01-01

    The genotoxic effect of radio marked lymphocytes was evaluated using 99m -Tc-HMPAO and 99m -Tc- gentisic acid complexes. With the results of this work it is pretended to contribute to the knowledge of genetic and structural damages that provokes the radiation in the marked lymphocytes. The d, 1-HMPAO was synthesized in laboratory with a yielding of 30 %. The radiochemical purity of the complexes was greater than 85%. Mouse lymphocytes obtained of sanguineous volumes 2 ml were used. The radio marked efficiency of cells was 19.6 ± 6.4% and 25.6 ± 5.8% for 99m Tc-HMPAO and 99m Tc gentisic acid respectively. The genotoxic effect was evaluated using the technique of Unicellular Electrophoresis in Micro gel (Comet assay). The results showed that both 99m Tc complexes produce genotoxicity due to their capacity to penetrate cells, therefore the Auger and M internal conversion electrons place all their energy obtaining doses of Gray order. (Author)

  1. Diffraction-based overlay measurement on dedicated mark using rigorous modeling method

    Science.gov (United States)

    Lu, Hailiang; Wang, Fan; Zhang, Qingyun; Chen, Yonghui; Zhou, Chang

    2012-03-01

    Diffraction Based Overlay (DBO) is widely evaluated by numerous authors, results show DBO can provide better performance than Imaging Based Overlay (IBO). However, DBO has its own problems. As well known, Modeling based DBO (mDBO) faces challenges of low measurement sensitivity and crosstalk between various structure parameters, which may result in poor accuracy and precision. Meanwhile, main obstacle encountered by empirical DBO (eDBO) is that a few pads must be employed to gain sufficient information on overlay-induced diffraction signature variations, which consumes more wafer space and costs more measuring time. Also, eDBO may suffer from mark profile asymmetry caused by processes. In this paper, we propose an alternative DBO technology that employs a dedicated overlay mark and takes a rigorous modeling approach. This technology needs only two or three pads for each direction, which is economic and time saving. While overlay measurement error induced by mark profile asymmetry being reduced, this technology is expected to be as accurate and precise as scatterometry technologies.

  2. Deposition in St. Mark's Basilica of Venice.

    Science.gov (United States)

    Morabito, E; Zendri, E; Piazza, R; Ganzerla, R; Montalbani, S; Marcoleoni, E; Bonetto, F; Scandella, A; Barbante, C; Gambaro, A

    2013-04-01

    Atmospheric pollutants may cause damage to monuments and historical buildings. Besides air contaminants, soluble salts are also responsible for stone deterioration and decay in outdoor and indoor monuments. The problem of how to conserve works of arts thus requires a deep knowledge of contaminants' concentration and distribution inside buildings. In this work, water-soluble ions inside St. Mark's Basilica in Venice were studied, with the aim of understanding their principal source and distribution inside the building. With the aid of Fourier transform infrared spectroscopy and scanning electron microscopy analysis, the interaction between ions and surface's material was also investigated. Ion chromatographic analysis of depositions highlighted a large amount of "deteriorating agents" such as sulphates and chlorides. A possible source in the innermost area of the basilica has been found for formates and nitrates. On the contrary, a decrease of chloride, from the entrance to the innermost area, has been found, which indicates that the source is outside the building. It is emphasized that different contaminants behave differently on different material, and the effect of pollution inside churches and monuments is not easy to predict. Wood and brick seem to react differently than stone and mortar to the damaging action of salts and pollutants. The present work should be considered a useful tool for the future preservation of St. Mark's Basilica in Venice.

  3. Dispersion Differences and Consistency of Artificial Periodic Structures.

    Science.gov (United States)

    Cheng, Zhi-Bao; Lin, Wen-Kai; Shi, Zhi-Fei

    2017-10-01

    Dispersion differences and consistency of artificial periodic structures, including phononic crystals, elastic metamaterials, as well as periodic structures composited of phononic crystals and elastic metamaterials, are investigated in this paper. By developing a K(ω) method, complex dispersion relations and group/phase velocity curves of both the single-mechanism periodic structures and the mixing-mechanism periodic structures are calculated at first, from which dispersion differences of artificial periodic structures are discussed. Then, based on a unified formulation, dispersion consistency of artificial periodic structures is investigated. Through a comprehensive comparison study, the correctness for the unified formulation is verified. Mathematical derivations of the unified formulation for different artificial periodic structures are presented. Furthermore, physical meanings of the unified formulation are discussed in the energy-state space.

  4. Differently Structured Advance Organizers Lead to Different Initial Schemata and Learning Outcomes

    Science.gov (United States)

    Gurlitt, Johannes; Dummel, Sebastian; Schuster, Silvia; Nuckles, Matthias

    2012-01-01

    Does the specific structure of advance organizers influence learning outcomes? In the first experiment, 48 psychology students were randomly assigned to three differently structured advance organizers: a well-structured, a well-structured and key-concept emphasizing, and a less structured advance organizer. These were followed by a sorting task, a…

  5. Sex differences in human epilepsy.

    Science.gov (United States)

    Savic, Ivanka

    2014-09-01

    In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. Emerging data suggest that gender differences exist also in the epidemiology, and pathophysiology of epilepsy. The present review summarizes the current information regarding gender and epilepsy. These differences are regarded from the perspective of innate sex differences in cerebral morphology, structural and functional connections, and assuming that these differences may render men and women differently vulnerable to epileptogenicity. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Mark II magnetic detector for SPEAR

    International Nuclear Information System (INIS)

    Larsen, R.R.

    1975-01-01

    The Mark II Detector, presently in the design stage, is a SLAC/LBL detector project to replace the Mark I now in operation at SPEAR. While similar in concept to the Mark I it will have improved momentum resolution, shower detection, solid angle coverage for both triggering and tracking and a magnet design providing easier access to those particles transmitted through the aluminum coil

  7. Mark Napier / Mark Napier ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Napier, Mark

    2006-01-01

    Ameerika kunstnikust Mark Napierist (sünd. 1961) ja tema loomingust, 2001. a. tehtud meiliintervjuu kunstnikuga. Võrguteosest "The Digital Landfill" (1998), koos Andy Deckiga loodud tööst "GrafficJam" (1999), töödest "Shredder" (1998), "Feed", "Riot", "P-Soup" (2000), võrgukunstist ja muust

  8. Helicobacter pylori CagA Inhibits PAR1-MARK Family Kinases by Mimicking Host Substrates

    Energy Technology Data Exchange (ETDEWEB)

    Nesic, D.; Miller, M; Quinkert, Z; Stein, M; Chait, B; Stebbins, C

    2010-01-01

    The CagA protein of Helicobacter pylori interacts with numerous cellular factors and is associated with increased virulence and risk of gastric carcinoma. We present here the cocrystal structure of a subdomain of CagA with the human kinase PAR1b/MARK2, revealing that a CagA peptide mimics substrates of this kinase family, resembling eukaryotic protein kinase inhibitors. Mutagenesis of conserved residues central to this interaction renders CagA inactive as an inhibitor of MARK2.

  9. Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant.

    Directory of Open Access Journals (Sweden)

    Tobias Ahsendorf

    Full Text Available The DNA microstates that regulate transcription include sequence-specific transcription factors (TFs, coregulatory complexes, nucleosomes, histone modifications, DNA methylation, and parts of the three-dimensional architecture of genomes, which could create an enormous combinatorial complexity across the genome. However, many proteins and epigenetic marks are known to colocalize, suggesting that the information content encoded in these marks can be compressed. It has so far proved difficult to understand this compression in a systematic and quantitative manner. Here, we show that simple linear models can reliably predict the data generated by the ENCODE and Roadmap Epigenomics consortia. Further, we demonstrate that a small number of marks can predict all other marks with high average correlation across the genome, systematically revealing the substantial information compression that is present in different cell lines. We find that the linear models for activating marks are typically cell line-independent, while those for silencing marks are predominantly cell line-specific. Of particular note, a nuclear receptor corepressor, transducin beta-like 1 X-linked receptor 1 (TBLR1, was highly predictive of other marks in two hematopoietic cell lines. The methodology presented here shows how the potentially vast complexity of TFs, coregulators, and epigenetic marks at eukaryotic genes is highly redundant and that the information present can be compressed onto a much smaller subset of marks. These findings could be used to efficiently characterize cell lines and tissues based on a small number of diagnostic marks and suggest how the DNA microstates, which regulate the expression of individual genes, can be specified.

  10. 78 FR 62323 - MarkWest Liberty Ethane Pipeline L.L.C.; Notice of Petition for Declaratory Order

    Science.gov (United States)

    2013-10-16

    ... Ethane Pipeline L.L.C.; Notice of Petition for Declaratory Order Take notice that on October 3, 2013...), MarkWest Liberty Ethane Pipeline L.L.C. (MarkWest) filed a petition requesting a declaratory order approving the overall tariff and rate structure for a new ethane pipeline system that will transport ethane...

  11. Limited Awareness of the Essences of Certification or Compliance Markings on Medical Devices.

    Science.gov (United States)

    Foo, Jong Yong Abdiel; Tan, Xin Ji Alan

    2017-06-01

    Medical devices have been long used for odiagnostic, therapeutic or rehabilitation purposes. Currently, they can range from a low-cost portable device that is often used for personal health monitoring to high-end sophisticated equipment that can only be operated by trained professionals. Depending on the functional purposes, there are different certification or compliance markings on the device when it is sold. One common certification marking is the Conformité Européenne affixation but this has a range of certification mark numbering for a variety of functional purposes. While the regulators and medical device manufacturers understand the associated significance and clinical implications, these may not be apparent to the professionals (using or maintaining the device) and the general public. With portable healthcare devices and mobile applications gaining popularity, better awareness of certification marking will be needed. Particularly, there are differences in the allowed functional purposes and the associated cost derivations of devices with a seemingly similar nature. A preferred approach such as an easy-to-understand notation next to any certification marking on a device can aid in differentiation without the need to digest mountainous regulatory details.

  12. Decommissioning of TRIGA Mark II type reactor

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Dooseong; Jeong, Gyeonghwan; Moon, Jeikwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-10-15

    The first research reactor in Korea, KRR 1, is a TRIGA Mark II type with open pool and fixed core. Its power was 100 kWth at its construction and it was upgraded to 250 kWth. Its construction was started in 1957. The first criticality was reached in 1962 and it had been operated for 36,000 hours. The second reactor, KRR 2, is a TRIGA Mark III type with open pool and movable core. These reactors were shut down in 1995, and the decision was made to decommission both reactors. The aim of the decommissioning activities is to decommission the KRR 2 reactor and decontaminate the residual building structures and site, and to release them as unrestricted areas. The KRR 1 reactor was decided to be preserve as a historical monument. A project was launched for the decommissioning of these reactors in 1997, and approved by the regulatory body in 2000. A total budget for the project was 20.0 million US dollars. It was anticipated that this project would be completed and the site turned over to KEPCO by 2010. However, it was discovered that the pool water of the KRR 1 reactor was leaked into the environment in 2009. As a result, preservation of the KRR 1 reactor as a monument had to be reviewed, and it was decided to fully decommission the KRR 1 reactor. Dismantling of the KRR 1 reactor takes place from 2011 to 2014 with a budget of 3.25 million US dollars. The scope of the work includes licensing of the decommissioning plan change, removal of pool internals including the reactor core, removal of the thermal and thermalizing columns, removal of beam port tubes and the aluminum liner in the reactor tank, removal of the radioactive concrete (the entire concrete structure will not be demolished), sorting the radioactive waste (concrete and soil) and conditioning the radioactive waste for final disposal, and final statuses of the survey and free release of the site and building, and turning over the site to KEPCO. In this paper, the current status of the TRIGA Mark-II type reactor

  13. AUTOMATIC EXTRACTION OF ROAD MARKINGS FROM MOBILE LASER SCANNING DATA

    Directory of Open Access Journals (Sweden)

    H. Ma

    2017-09-01

    Full Text Available Road markings as critical feature in high-defination maps, which are Advanced Driver Assistance System (ADAS and self-driving technology required, have important functions in providing guidance and information to moving cars. Mobile laser scanning (MLS system is an effective way to obtain the 3D information of the road surface, including road markings, at highway speeds and at less than traditional survey costs. This paper presents a novel method to automatically extract road markings from MLS point clouds. Ground points are first filtered from raw input point clouds using neighborhood elevation consistency method. The basic assumption of the method is that the road surface is smooth. Points with small elevation-difference between neighborhood are considered to be ground points. Then ground points are partitioned into a set of profiles according to trajectory data. The intensity histogram of points in each profile is generated to find intensity jumps in certain threshold which inversely to laser distance. The separated points are used as seed points to region grow based on intensity so as to obtain road mark of integrity. We use the point cloud template-matching method to refine the road marking candidates via removing the noise clusters with low correlation coefficient. During experiment with a MLS point set of about 2 kilometres in a city center, our method provides a promising solution to the road markings extraction from MLS data.

  14. Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs

    Directory of Open Access Journals (Sweden)

    Vik-Mo Audun O

    2006-10-01

    Full Text Available Abstract Background The etiology of schizophrenia is unknown, but neurodevelopmental disturbances, myelin- and oligodendrocyte abnormalities and synaptic dysfunction have been suggested as pathophysiological factors in this severe psychiatric disorder. Cholesterol is an essential component of myelin and has proved important for synapse formation. Recently, we demonstrated that the antipsychotic drugs clozapine and haloperidol stimulate lipogenic gene expression in cultured glioma cells through activation of the sterol regulatory element-binding protein (SREBP transcription factors. We here compare the action of chlorpromazine, haloperidol, clozapine, olanzapine, risperidone and ziprasidone on SREBP activation and SREBP-controlled gene expression (ACAT2, HMGCR, HMGCS1, FDPS, SC5DL, DHCR7, LDLR, FASN and SCD1 in four CNS-relevant human cell lines. Results There were marked differences in the ability of the antipsychotic drugs to activate the expression of SREBP target genes, with clozapine and chlorpromazine as the most potent stimulators in a context of therapeutically relevant concentrations. Glial-like cells (GaMg glioma and CCF-STTG1 astrocytoma cell lines displayed more pronounced drug-induced SREBP activation compared to the response in HCN2 human cortical neurons and SH-SY5Y neuroblastoma cells, indicating that antipsychotic-induced activation of lipogenesis is most prominent in glial cells. Conclusion Our present data show a marked variation in the ability of different antipsychotics to induce SREBP-controlled transcriptional activation of lipogenesis in cultured human CNS-relevant cells. We propose that this effect could be relevant for the therapeutic efficacy of some antipsychotic drugs.

  15. Percentage Retail Mark-Ups

    OpenAIRE

    Thomas von Ungern-Sternberg

    1999-01-01

    A common assumption in the literature on the double marginalization problem is that the retailer can set his mark-up only in the second stage of the game after the producer has moved. To the extent that the sequence of moves is designed to reflect the relative bargaining power of the two parties it is just as plausible to let the retailer move first. Furthermore, retailers frequently calculate their selling prices by adding a percentage mark-up to their wholesale prices. This allows a retaile...

  16. XML schemas and mark-up practices of taxonomic literature.

    Science.gov (United States)

    Penev, Lyubomir; Lyal, Christopher Hc; Weitzman, Anna; Morse, David R; King, David; Sautter, Guido; Georgiev, Teodor; Morris, Robert A; Catapano, Terry; Agosti, Donat

    2011-01-01

    We review the three most widely used XML schemas used to mark-up taxonomic texts, TaxonX, TaxPub and taXMLit. These are described from the viewpoint of their development history, current status, implementation, and use cases. The concept of "taxon treatment" from the viewpoint of taxonomy mark-up into XML is discussed. TaxonX and taXMLit are primarily designed for legacy literature, the former being more lightweight and with a focus on recovery of taxon treatments, the latter providing a much more detailed set of tags to facilitate data extraction and analysis. TaxPub is an extension of the National Library of Medicine Document Type Definition (NLM DTD) for taxonomy focussed on layout and recovery and, as such, is best suited for mark-up of new publications and their archiving in PubMedCentral. All three schemas have their advantages and shortcomings and can be used for different purposes.

  17. Laser marking method and device

    International Nuclear Information System (INIS)

    Okazaki, Yuki; Aoki, Nobutada; Mukai, Narihiko; Sano, Yuji; Yamamoto, Seiji.

    1997-01-01

    An object is disposed in laser beam permeating liquid or gaseous medium. Laser beams such as CW laser or pulse laser oscillated from a laser device are emitted to the object to apply laser markings with less degradation of identification and excellent corrosion resistance on the surface of the object simply and easily. Upon applying the laser markings, a liquid or gas as a laser beam permeating medium is blown onto the surface of the object, or the liquid or gas in the vicinity of the object is sucked, the laser beam-irradiated portion on the surface can be cooled positively. Accordingly, the laser marking can be formed on the surface of the object with less heat affection to the object. In addition, if the content of a nitrogen gas in the laser beam permeating liquid medium is reduced by degassing to lower than a predetermined value, or the laser beam permeating gaseous medium is formed by an inert gas, a laser marking having high corrosion resistance and reliability can be formed on the surface of the objective member. (N.H.)

  18. Identification of the Nile crocodile Crocodylus niloticus by the use of natural tail marks

    Directory of Open Access Journals (Sweden)

    D.G.J. Swanepoel

    1996-08-01

    Full Text Available The tail marks of 190 Nile crocodiles Crocodylus niloticus were documented and processed into codes. The size of the crocodiles varied from 45 cm to 4.6 m in total length. Wherever possible, both sides of the tails were observed and the marks documented. In all remaining instances only one side could be identified. A total of 267 sides were identified. The natural marks on nine segments of a specific portion of the tail was recorded and compared as codes. For this comparison two methods were employed. Differences of 95.1 and 100 was found with the respective methods. This is an indication that every crocodile has a unique pattern of natural marks on its tail. The marks can therefore be used to allocate a code to an individual crocodile that partially eliminates the necessity of artificial marking methods.

  19. Identification of the Nile crocodile Crocodylus niloticus by the use of natural tail marks

    Directory of Open Access Journals (Sweden)

    D.G.J. Swanepoel

    1996-01-01

    Full Text Available The tail marks of 190 Nile crocodiles Crocodylus niloticus were documented and processed into codes. The size of the crocodiles varied from 45 cm to 4.6 m in total length. Wherever possible, both sides of the tails were observed and the marks documented. In all remaining instances only one side could be identified. A total of 267 sides were identified. The natural marks on nine segments of a specific portion of the tail was recorded and compared as codes. For this comparison two methods were employed. Differences of 95.1 and 100 was found with the respective methods. This is an indication that every crocodile has a unique pattern of natural marks on its tail. The marks can therefore be used to allocate a code to an individual crocodile that partially eliminates the necessity of artificial marking methods.

  20. Mark I containment long-term program safety evaluation report, resolution of generic technical activity A-7. Report for February 1977-December 1979

    International Nuclear Information System (INIS)

    1980-07-01

    During testing for an advanced Boiling Water Reactor (BWR) containment system design (Mark III), suppression pool hydrodynamic loads were identified which had not been considered in the original design of the Mark I containment system. To address this issue, a Mark I Owners Group was formed and the assessment was divided into a short-term and long-term program. The results of the NRC staff's review of the Mark I Containment Short Term Program are described in NUREG-0408. This report describes the results of the NRC staff's review of the generic Mark I Containment Long Term Program (LTP). The LTP was conducted to provide a generic basis to define suppression pool hydrodynamic loads and the related structural acceptance criteria, such that a comprehensive reassessment of each Mark I containment system would be performed. A series of experimental and analytical programs were conducted by the Mark I Owners Group to provide the necessary bases for the generic load definition and structural assessment techniques. The generic methods proposed by the Mark I Owners Group, as modified by the NRC staff's requirements, will be used to perform plant-unique analyses, which will identify the plant modifications, if any, that will be needed to restore the originally intended margin of safety in the Mark I containment designs

  1. Cooperative Shark Mark Recapture Database (MRDBS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Shark Mark Recapture Database is a Cooperative Research Program database system used to keep multispecies mark-recapture information in a common format for...

  2. MarkIT büroo = Offices of MarkIT

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Pärnu mnt. 102C asuvas büroohoones paikneva MarkIT büroo sisekujundusest. Sisearhitektid Kard Männil (SAB Miu Miu Miu) ja Loreida Hein (Studio La), nende tähtsamate tööde loetelu. Valge büroomööbel on sisearhitektide projekteeritud. Graafika on sisearhitektid ise joonistanud

  3. User’s guide for MapMark4GUI—A graphical user interface for the MapMark4 R package

    Science.gov (United States)

    Shapiro, Jason

    2018-05-29

    MapMark4GUI is an R graphical user interface (GUI) developed by the U.S. Geological Survey to support user implementation of the MapMark4 R statistical software package. MapMark4 was developed by the U.S. Geological Survey to implement probability calculations for simulating undiscovered mineral resources in quantitative mineral resource assessments. The GUI provides an easy-to-use tool to input data, run simulations, and format output results for the MapMark4 package. The GUI is written and accessed in the R statistical programming language. This user’s guide includes instructions on installing and running MapMark4GUI and descriptions of the statistical output processes, output files, and test data files.

  4. A model for transmission of the H3K27me3 epigenetic mark

    DEFF Research Database (Denmark)

    Hansen, Klaus H; Bracken, Adrian P; Pasini, Diego

    2008-01-01

    Organization of chromatin by epigenetic mechanisms is essential for establishing and maintaining cellular identity in developing and adult organisms. A key question that remains unresolved about this process is how epigenetic marks are transmitted to the next cell generation during cell division...... during incorporation of newly synthesized histones. This mechanism ensures maintenance of the H3K27me3 epigenetic mark in proliferating cells, not only during DNA replication when histones synthesized de novo are incorporated, but also outside S phase, thereby preserving chromatin structure...

  5. Minimal Marking: A Success Story

    Directory of Open Access Journals (Sweden)

    Anne McNeilly

    2014-11-01

    Full Text Available The minimal-marking project conducted in Ryerson’s School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The “minimal-marking” concept (Haswell, 1983, which requires dramatically more student engagement, resulted in more successful learning outcomes for surface-level knowledge acquisition than the more traditional approach of “teacher-corrects-all.” Results suggest it would be effective, not just for grammar, punctuation, and word usage, the objective here, but for any material that requires rote-memory learning, such as the Associated Press or Canadian Press style rules used by news publications across North America.

  6. Unequal Probability Marking Approach to Enhance Security of Traceback Scheme in Tree-Based WSNs.

    Science.gov (United States)

    Huang, Changqin; Ma, Ming; Liu, Xiao; Liu, Anfeng; Zuo, Zhengbang

    2017-06-17

    Fog (from core to edge) computing is a newly emerging computing platform, which utilizes a large number of network devices at the edge of a network to provide ubiquitous computing, thus having great development potential. However, the issue of security poses an important challenge for fog computing. In particular, the Internet of Things (IoT) that constitutes the fog computing platform is crucial for preserving the security of a huge number of wireless sensors, which are vulnerable to attack. In this paper, a new unequal probability marking approach is proposed to enhance the security performance of logging and migration traceback (LM) schemes in tree-based wireless sensor networks (WSNs). The main contribution of this paper is to overcome the deficiency of the LM scheme that has a higher network lifetime and large storage space. In the unequal probability marking logging and migration (UPLM) scheme of this paper, different marking probabilities are adopted for different nodes according to their distances to the sink. A large marking probability is assigned to nodes in remote areas (areas at a long distance from the sink), while a small marking probability is applied to nodes in nearby area (areas at a short distance from the sink). This reduces the consumption of storage and energy in addition to enhancing the security performance, lifetime, and storage capacity. Marking information will be migrated to nodes at a longer distance from the sink for increasing the amount of stored marking information, thus enhancing the security performance in the process of migration. The experimental simulation shows that for general tree-based WSNs, the UPLM scheme proposed in this paper can store 1.12-1.28 times the amount of stored marking information that the equal probability marking approach achieves, and has 1.15-1.26 times the storage utilization efficiency compared with other schemes.

  7. Gender Differences in the Structure of Marital Quality.

    Science.gov (United States)

    Beam, Christopher R; Marcus, Katherine; Turkheimer, Eric; Emery, Robert E

    2018-05-01

    Marriages consist of shared experiences and interactions between husbands and wives that may lead to different impressions of the quality of the relationship. Few studies, unfortunately, have tested gender differences in the structure of marital quality, and even fewer studies have evaluated whether genetic and environmental influences on marital quality differ across gender. In this study, we evaluated gender differences in the structure of marital quality using independent samples of married male (n = 2406) and married female (n = 2215) participants from the National Survey of Midlife Development in the United States who provided ratings on twenty-eight marital quality items encompassing six marital quality constructs. We further explored gender differences in genetic and environmental influences on marital quality constructs in a subsample of 491 pairs of twins. Results suggest partial metric invariance across gender but structural variability in marital quality constructs. Notably, correlations between constructs were stronger in women than men. Results also support gender differences in the genetic and environmental influences on different aspects of marital quality. We discuss that men and women may approach and react to marriage differently as the primary reason why we observed differences in the structure of marital quality.

  8. Computational analysis of neutronic parameters of CENM TRIGA Mark II research reactor

    International Nuclear Information System (INIS)

    El Younoussi, C.; El Bakkari, B.; Boulaich, Y.; Riyach, D.; Otmani, S.; Marrhich, I.; Badri, H.; Htet, A.; Nacir, B.; El Bardouni, T.; Boukhal, H.; Zoubair, M.; Ossama, M.; Chakir, E.

    2010-01-01

    The CENM TRIGA MARK II reactor is part of the National Center for Energy, Sciences and Nuclear Techniques (CNESTEN). It's a standard design 2MW, natural-convection-cooled reactor with a graphite reflector containing 4 beam tubes and a thermal column. The reactor has several applications in different fields as industry, agriculture, medicine, training and education. In the present work a computational study has been carried out in the framework of neutronic parameters studies of the reactor. A detailed MCNP model that include all elements of the core and surrounding structures has been developed to calculate different parameters of the core (The effective multiplication factor, reactivity experiments comprising control rods worth, excess reactivity and shutdown margin). Further calculations have been carried out to calculate the neutron flux profiles at different locations of the reactor core. The cross sections used are processed from the library provided with MCNP5 and based on the ENDF/B-VII with continuous dependence in energy and special treatment of thermal neutrons in lightweight materials. (author)

  9. Prayer marks.

    Science.gov (United States)

    Abanmi, Abdullah A; Al Zouman, Abdulrahman Y; Al Hussaini, Husa; Al-Asmari, Abdulrahman

    2002-07-01

    Prayer marks (PMs) are asymptomatic, chronic skin changes that consist mainly of thickening, lichenification, and hyperpigmentation, and develop over a long period of time as a consequence of repeated, extended pressure on bony prominences during prayer. Three hundred and forty-nine Muslims and 24 non-Muslims were examined for the appearance of PMs at different body sites. The prospective study of 349 Muslims (both males and females) with regular praying habits showed the occurrence of PMs on specific locations, such as the forehead, knees, ankles, and dorsa of the feet, leading to dermatologic changes consisting of lichenification and hyperpigmentation. The incidence of PMs was significantly higher in males than in females. Older subjects (over 50 years of age) demonstrated a significantly higher frequency of lichenification and hyperpigmentation, suggesting that repeated pressure and friction for prolonged periods are the causative factors for the development of PMs. Histologic examination of skin biopsies from the affected sites showed compact orthokeratosis, hypergranulosis, dermal papillary fibrosis, and dermal vascularization. PMs were not associated with any risk of secondary complications, such as erythema, bullous formation, and infections. PMs are commonly occurring dermatologic changes in Muslims who pray for prolonged periods.

  10. The examination and identification of bite marks in foods using 3D scanning and 3D comparison methods.

    Science.gov (United States)

    Naether, Silvio; Buck, Ursula; Campana, Lorenzo; Breitbeck, Robert; Thali, Michael

    2012-01-01

    Bite mark analysis offers the opportunity to identify the biter based on the individual characteristics of the dentitions. Normally, the main focus is on analysing bite mark injuries on human bodies, but also, bite marks in food may play an important role in the forensic investigation of a crime. This study presents a comparison of simulated bite marks in different kinds of food with the dentitions of the presumed biter. Bite marks were produced by six adults in slices of buttered bread, apples, different kinds of Swiss chocolate and Swiss cheese. The time-lapse influence of the bite mark in food, under room temperature conditions, was also examined. For the documentation of the bite marks and the dentitions of the biters, 3D optical surface scanning technology was used. The comparison was performed using two different software packages: the ATOS modelling and analysing software and the 3D studio max animation software. The ATOS software enables an automatic computation of the deviation between the two meshes. In the present study, the bite marks and the dentitions were compared, as well as the meshes of each bite mark which were recorded in the different stages of time lapse. In the 3D studio max software, the act of biting was animated to compare the dentitions with the bite mark. The examined food recorded the individual characteristics of the dentitions very well. In all cases, the biter could be identified, and the dentitions of the other presumed biters could be excluded. The influence of the time lapse on the food depends on the kind of food and is shown on the diagrams. However, the identification of the biter could still be performed after a period of time, based on the recorded individual characteristics of the dentitions.

  11. An analysis of hospital brand mark clusters.

    Science.gov (United States)

    Vollmers, Stacy M; Miller, Darryl W; Kilic, Ozcan

    2010-07-01

    This study analyzed brand mark clusters (i.e., various types of brand marks displayed in combination) used by hospitals in the United States. The brand marks were assessed against several normative criteria for creating brand marks that are memorable and that elicit positive affect. Overall, results show a reasonably high level of adherence to many of these normative criteria. Many of the clusters exhibited pictorial elements that reflected benefits and that were conceptually consistent with the verbal content of the cluster. Also, many clusters featured icons that were balanced and moderately complex. However, only a few contained interactive imagery or taglines communicating benefits.

  12. Glass marking with diode-pumped Nd:YLF laser; Handotai reiki Nd:YLF laser ni yoru glass marking

    Energy Technology Data Exchange (ETDEWEB)

    Sakai, F.; Hayashi, K. [Sumitomo Heavy Industries, Ltd., Tokyo (Japan)

    1996-08-20

    The compact marking system based on a beam scanning system in which the fourth harmonic (FHG: 262 nm in wavelength) of a diode-pumped Nd:YLF (Nd:LiYf4) laser is used for the source of ultraviolet light is described. The result of application to the glass marking that caused a problem due to the generation of cracks is also explained. The machining characteristics significantly vary depending on the type of glass. During actual marking, sample processing must be beforehand carried out to optimize the processing conditions after confirming that there is no problem in practical use. For marking on the glass used for liquid-crystal board, it is valid to improve the density of a dot and increase the number of shots per dot for obtaining high visibility. However, cracks may occur in the clearance of each dot because of the thermal effect. Therefore, the processing conditions must be optimized according to the glass type and crack generation state. The generation of cracks can be suppressed by setting the processing conditions to the optimum level. As a result, satisfactory marking is obtained. 8 refs., 6 figs.

  13. Mark 4A DSN receiver-exciter and transmitter subsystems

    Science.gov (United States)

    Wick, M. R.

    1986-01-01

    The present configuration of the Mark 4A DSN Receiver-Exciter and Transmitter Subsystems is described. Functional requirements and key characteristics are given to show the differences in the capabilities required by the Networks Consolidation task for combined High Earth Orbiter and Deep Space Network tracking support.

  14. Civilsamfundets ABC: M for Marked

    DEFF Research Database (Denmark)

    Lund, Anker Brink; Meyer, Gitte

    2016-01-01

    Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked.......Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked....

  15. 19 CFR 134.43 - Methods of marking specific articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Methods of marking specific articles. 134.43...; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Method and Location of Marking Imported Articles § 134.43 Methods of marking specific articles. (a) Marking previously required by certain provisions of the...

  16. Lessons learned : pavement marking warranty contract.

    Science.gov (United States)

    2013-12-01

    In 2012, UDOT implemented a performance-based warranty on a portion of an I-15 pavement marking : project. The awarded contract requested a contractor warranty on the implemented markings for a total : duration of six years. This is the first time th...

  17. Safety/relief valve quencher loads: evaluation for BWR Mark II and III containments

    International Nuclear Information System (INIS)

    Su, T.M.

    1982-10-01

    Boiling water reactor (BWR) plants are equipped with safety/relief valves (SRVs) to protect the reactor from overpressurization. Plant operational transients, such as turbine trips, will actuate the SRV. Once the SRV opens, the air column within the partially submerged discharge line is compressed by the high-pressure steam released from the reactor. The compressed air discharged into the suppression pool produces high-pressure bubbles. Oscillatory expansion and contraction of these bubbles create hydrodynamic loads on the containment structures, piping, and equipment inside containment. This report presents the results of the staff's evaluation of SRV loads. The evaluation, however, is limited to the quencher devices used in Mark II and III containments. With respect to Mark I containments, the SRV acceptance criteria are presented in NUREG-0661 issued July 1980. The staff acceptance criteria for SRV loads for Mark II and III containments are presented in this report

  18. Marked bengal pink. A dynamic test using marking doses; its value in jaundice diagnosis

    International Nuclear Information System (INIS)

    Kellershohn, C.; Desgrez, A.; Delaloye, B.

    1961-01-01

    The authors do a historic calling back of the differential study of jaundices thanks to the semi logarithmic gradients of expurgation of bromine sulphone-phthalein and thanks to the time of appearance of this material in the bile collected by duodenal tubing. They sum up likewise the foreign works which lead to take the place of this test, the outside count at the level of the head, the liver, and the abdomen after intravenous injection of a running dose of marked Rose Bengal. They specify the technical conditions of this test and report an experience which corroborate its value, its accuracy and the interest of its using in the different types of jaundices (hepatitis and obstructive types). (author) [fr

  19. Minnesota Local Agency Pavement Marking : Mining Existing Data

    Science.gov (United States)

    2017-11-01

    Pavement marking is important for safety. Maximizing pavement marking performance in terms of increased retroreflectivity, within limited budget constraints, allows agencies to make better decisions toward providing more effective pavement marking pe...

  20. Cavernous hemangioma presenting marked hyperostosis

    International Nuclear Information System (INIS)

    Kobata, Hitoshi; Miyake, Hiroji; Kitamura, Junji; Kajikawa, Hiroshi; Ohta, Tomio

    1988-01-01

    The authors report here a case of hemangioma of the left parietal bone which presented headache and papilledema. This patient is a 37-year-old female who had, prior to admission, complained of increasing headache for one year and blurred vision for three months. She had no history of head injury. Local physical examinations revealed a slight bulging in her left parietal region which was insensitive to palpation and not adherent to the overlying scalp. Neurological examinations revealed bilateral papilledema and an incongruous bitemporal upper quadrant defect in the visual field. All the other neurological and laboratory data were normal. A plain skull roentogenogram showed a 9 x 9 cm osteolytic and characteristic honeycomb lesion in the parietal region. Systemic bone survey revealed a similar lesion in the right tibia which was not histologically examined. A marked accumulation of isotopes was detected on the bone scintigrams at both lesions. Selective external carotid angiograms demonstrated a tumor stain fed by the superficial temporal, occipital, and middle meningial arteries. CT scans of the brain and skull clearly showed a local thickening of and structural changes in the skull bone and also a mass effect on the brain and lateral ventricle. The lesioned bone was removed en bloc and replaced by an artificial bone. It was highly vascular, but not adherent to the overlying dura. The post-operative course was uneventful, and the headache and papilledema disappeared. Hemangioma of the skull presenting marked hyperostosis, as reported above, seems to be rare. In addition, in this case, skeletal angioma without any clinical manifestation was detected. Clinical and radiological pictures of the hemangioma of the skull and other bones were briefly discussed. (author)

  1. Identifying persistent and characteristic features in firearm tool marks on cartridge cases

    Science.gov (United States)

    Ott, Daniel; Soons, Johannes; Thompson, Robert; Song, John

    2017-12-01

    Recent concerns about subjectivity in forensic firearm identification have motivated the development of algorithms to compare firearm tool marks that are imparted on ammunition and to generate quantitative measures of similarity. In this paper, we describe an algorithm that identifies impressed tool marks on a cartridge case that are both consistent between firings and contribute strongly to a surface similarity metric. The result is a representation of the tool mark topography that emphasizes both significant and persistent features across firings. This characteristic surface map is useful for understanding the variability and persistence of the tool marks created by a firearm and can provide improved discrimination between the comparison scores of samples fired from the same firearm and the scores of samples fired from different firearms. The algorithm also provides a convenient method for visualizing areas of similarity that may be useful in providing quantitative support for visual comparisons by trained examiners.

  2. Do employers prefer Mark over Mohammed?

    NARCIS (Netherlands)

    Iris Andriessen; Eline Nievers; Laila Faulk; Jaco Dagevos

    2010-01-01

    Original title: Liever Mark dan Mohammed? Does Mohammed have less chance of succeeding on the Dutch labour market than Mark, even though they both have the same qualifications and work experience? And are employers less friendly towards Sonaya than Paula? This study investigates the

  3. Structural differences between native Hen egg white lysozyme and its fibrils under different environmental conditions

    Science.gov (United States)

    Bhattacharya, Susmita; Ghosh, Sudeshna; Dasgupta, Swagata; Roy, Anushree

    2013-10-01

    The difference in molecular structure of native HEWL and its fibrils, grown at a pH value near physiological pH 7.4 and at a pH value just above the pI, 10.7 in presence and absence of Cu(II) ions, is discussed. We focus on differences between the molecular structure of the native protein and fibrils using principal component analysis of their Raman spectra. The overlap areas of the scores of each species are used to quantify the difference in the structure of the native HEWL and fibrils in different environments. The overall molecular structures are significantly different for fibrils grown at two pH values. However, in presence of Cu(II) ions, the fibrils have similarities in their molecular structures at these pH environments. Spectral variation within each species, as obtained from the standard deviations of the scores in PCA plots, reveals the variability in the structure within a particular species.

  4. [Werkgartner's muzzle imprint mark--a literature study].

    Science.gov (United States)

    Geserick, Gunther; Vendura, Klaus; Wirth, Ingo

    2009-01-01

    Since Werkgartner described and correctly interpreted the muzzle imprint mark around the gunshot entrance wound in 1922, this finding has been generally accepted as a sign of a contact shot. In further studies, it could finally be clarified that the muzzle imprint mark is caused by the expansive power of the powder gases with pressure on and abrasion of the skin at the muzzle (weapon imprint). Its shape depends on the firearm, the ammunition and the anatomical conditions, but does not require a bullet. Examinations under a magnifying glass microscope and histological investigations can complete the macroscopic findings. Occasionally, the muzzle imprint mark requires a certain "drying period" in order to become clearly visible. In rare cases, muzzle imprint marks also form on textiles perforated by the projectile. Characteristically shaped muzzled imprint marks can provide clues to the type of the firearm and its position at the time of discharge.

  5. The Perrillo Mark of the Spanish Swordsmith Julián del Rey. Summary

    Directory of Open Access Journals (Sweden)

    Rodríguez Lorente, J. J.

    1964-12-01

    Full Text Available THE swordsmith mark in the form of a “little dog” or “wolf”, punched or stamped on the blade of the weapon, is comparatively ccmmon in Spanish rapiers of the XVIth Century, and even more common in swords of the same and later periods attributed to the German swordmakers of Passau and Solingen. The existence of these two different sources of weapons bearing a similar mark, and the lack of proper documentation on the Spanish swordsmiths of the period, creates a problem for the proper attribution of the swords bearing the above mark.

    No disponible.

  6. Edit distance for marked point processes revisited: An implementation by binary integer programming

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

    2015-12-15

    We implement the edit distance for marked point processes [Suzuki et al., Int. J. Bifurcation Chaos 20, 3699–3708 (2010)] as a binary integer program. Compared with the previous implementation using minimum cost perfect matching, the proposed implementation has two advantages: first, by using the proposed implementation, we can apply a wide variety of software and hardware, even spin glasses and coherent ising machines, to calculate the edit distance for marked point processes; second, the proposed implementation runs faster than the previous implementation when the difference between the numbers of events in two time windows for a marked point process is large.

  7. 19 CFR 11.9 - Special marking on certain articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Special marking on certain articles. 11.9 Section... OF THE TREASURY PACKING AND STAMPING; MARKING Marking § 11.9 Special marking on certain articles. (a... of additional U.S. Note 4, Chapter 91. If any article so required to be marked is found not to be...

  8. Influence of admission marks on the academic performance of technical architecture students

    OpenAIRE

    Gaspar Fàbregas, Kàtia; Núñez Andrés, María Amparo; Rodríguez Jordana, Juan; Jordana Riba, Francisco de Paula

    2016-01-01

    Traditionally, students from higher training cycle and upper secondary school education access higher technical education with a wide range of access marks in each group. The purpose of this article is to analyse how students’ backgrounds and access marks really influence their success in the first academic year and further evolution to obtain the degree of Technical Architecture. To achieve this aim, the progress of students from different backgrounds was analysed for three acade...

  9. Radiation-induced mutation frequency in marked chromosome of Macaca mulatta

    International Nuclear Information System (INIS)

    Dzhemilev, Z.A.; Machavariani, M.G.

    1976-01-01

    The symmetric and asymmetric exchange frequencies of marked (nucleolus forming) chromosomes were studied in the lymphocytes and epithelial kidney cells irradiated by X-rays at G 0 , both in vivo and in vitro. Symmetric and asymmetric exchange frequencies were found to be equal. In both the types of Macaca mulatta cells, the exchange frequency in the long arm appeared to be higher than theoretically expected. The increased exchange in the long arm is thought to be due to a greater quantity of late replicating heterochromatin in it. The short arm of marked chromosome of epithelial kidney cells enters the exchange in accordance to its length in mitosis, but exchange number in the short arm chromosome in lymphocytes is lower than in epithelial cells. This difference is caused likely by different functioning of the nucleolus forming heterochromatin. (author)

  10. RAPID INSPECTION OF PAVEMENT MARKINGS USING MOBILE LIDAR POINT CLOUDS

    Directory of Open Access Journals (Sweden)

    H. Zhang

    2016-06-01

    Full Text Available This study aims at building a robust semi-automated pavement marking extraction workflow based on the use of mobile LiDAR point clouds. The proposed workflow consists of three components: preprocessing, extraction, and classification. In preprocessing, the mobile LiDAR point clouds are converted into the radiometrically corrected intensity imagery of the road surface. Then the pavement markings are automatically extracted with the intensity using a set of algorithms, including Otsu’s thresholding, neighbor-counting filtering, and region growing. Finally, the extracted pavement markings are classified with the geometric parameters using a manually defined decision tree. Case studies are conducted using the mobile LiDAR dataset acquired in Xiamen (Fujian, China with different road environments by the RIEGL VMX-450 system. The results demonstrated that the proposed workflow and our software tool can achieve 93% in completeness, 95% in correctness, and 94% in F-score when using Xiamen dataset.

  11. Identifikasi bite marks dengan ekstraksi DNA metode Chelex (Bite marks identification with Chelex methods in DNA extraction

    Directory of Open Access Journals (Sweden)

    Imelda Kristina Sutrisno

    2013-06-01

    Full Text Available Background: In the case of crime often encountered evidence in bite marks form that was found on the victim’s body. Generally, bitemarks identification use standard techniques that compare the interpretation picture with the tooth model of suspected person. However, sometimes the techniques do not obtain accurate results. Therefore another technique is needed to support the identification process,such as DNA analysis that use the remaining epithelium attached in saliva to identify the DNA of the suspected person. In this processes a limited DNA material could be met, not only less in quantity but also less in quality. Chelex known as one of an effective DNA extraction method in DNA forensic case is needed to overcome this problem. Purpose: The study was aimed to examine the use of Chelex as DNA extraction method on a bitemarks sample models. Methods: The blood and bitemarks of 5 persons with were taken. The DNA of each subject was exctracted with Chelex and quantified the quantity with UV Spechtrophotometer. The DNA results was amplified by PCR at locus vWA and TH01 then vizualised by electrophoresis. Results: The electrophoresis’s results showed band at locus vWA and TH01 for blood sample and bite marks with no significant differences. Conclusion: The study showed that Chelex method could be use to extract DNA from bitemarks.Latar belakang: Dalam kasus kejahatan sering dijumpai bukti dalam bentuk bekas gigitan (bitemarks yang ditemukan pada tubuh korban. Umumnya, untuk mengidentifikasi bite marks menggunakan teknik standar yaitu membandingkan foto interpretasi dengan model gigi dari orang yang dicurigai. Namun demikian teknik ini terkadang tidak mendapatkan hasil yang akurat, sehingga diperlukan teknik lain untuk menunjang keberhasilan proses identifikasi pelaku, yakni melalui analisis DNA bitemarks, yang diperoleh dari saliva yang mengandung sisa epitel tersangka pelaku. Sampel DNA yang berasal dari bitemarks umumnya terbatas, tidak hanya

  12. 49 CFR 178.338-18 - Marking.

    Science.gov (United States)

    2010-10-01

    ... pounds. (7) Maximum design density of lading (Max. Lading density), in pounds per gallon. (8) Material... cryogenic liquid, in hours, and the name of that cryogenic liquid (MRHT __ hrs, name of cryogenic liquid). Marked rated holding marking for additional cryogenic liquids may be displayed on or adjacent to the...

  13. 7 CFR 956.162 - Container markings.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container markings. 956.162 Section 956.162... WALLA VALLEY OF SOUTHEAST WASHINGTON AND NORTHEAST OREGON Rules and Regulations § 956.162 Container markings. Effective April 15, 1997, no handler shall ship any container of Walla Walla Sweet Onions except...

  14. Different measures of structural similarity tap different aspects of visual object processing

    DEFF Research Database (Denmark)

    Gerlach, Christian

    2017-01-01

    The structural similarity of objects has been an important variable in explaining why some objects are easier to categorize at a superordinate level than to individuate, and also why some patients with brain injury have more difficulties in recognizing natural (structurally similar) objects than...... artifacts (structurally distinct objects). In spite of its merits as an explanatory variable, structural similarity is not a unitary construct, and it has been operationalized in different ways. Furthermore, even though measures of structural similarity have been successful in explaining task and category-effects...

  15. The electron irradiation effects in different structures of diodes

    International Nuclear Information System (INIS)

    Li Quanfen; Wang Jiaxu

    1993-01-01

    This paper describes the different electron irradiation effects in different structures of diodes and the different results produced by different irradiation ways. From this work, we can know how to choose proper manufacture arts and comprehensive factors according to the structures of diodes and the irradiation conditions

  16. Marks on the petroleum fiscality

    International Nuclear Information System (INIS)

    2007-02-01

    This document offers some marks on the petroleum fiscality in France: the taxes as the 'accises' and the 'TVA', the part of the taxes in the sale price at the service station, the comparison with other countries of Europe, the tax revenues and the Government budget. It provides also marks on the fuels prices formation (margins), the world petroleum markets (supply and demand) and the part of the petroleum companies on the petroleum market. (A.L.B.)

  17. 14 CFR 1203.501 - Applying derivative classification markings.

    Science.gov (United States)

    2010-01-01

    ... INFORMATION SECURITY PROGRAM Derivative Classification § 1203.501 Applying derivative classification markings. Persons who apply derivative classification markings shall: (a) Observe and respect original... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Applying derivative classification markings...

  18. Predatory behaviour of carnivorous dinosaurs: Ecological interpretations based on tooth marked dinosaur bones and wear patterns of theropod teeth

    DEFF Research Database (Denmark)

    Jacobsen, Aase Roland

    Predation marks on bones are a source on information on the feeding behaviour of the carnivores involved. Although predator damaged bone is common in the fossil record, published reports of such marks on dinosaur bones are rare. Patterns of bone modification by mammalian carnivores overlap patterns...... left by theropod dinosaurs.Differences in tooth morphology can also be correlated with characteristics of the marks left by the teeth. In a study of tooth marks on dinosaur bones from the Dinosaur Park Formation of Alberta, Canada, it was possible to identify the feeding theropods to family, generic...... different taxa and different skeletal elements produced some interesting results. The frequency of tooth marked dinosaur bones is higher than expected. Up to 14 % of the observed hadrosaur bones were predator damaged. The lower incidence of damage in ceratopsian bones can be explained by the fact...

  19. Aluminum-Oxide Temperatures on the Mark VB, VE, VR, 15, and Mark 25 Assemblies

    International Nuclear Information System (INIS)

    Aleman, S.E.

    2001-01-01

    The task was to compute the maximum aluminum-oxide and oxide-coolant temperatures of assemblies cladded in 99+ percent aluminum. The assemblies considered were the Mark VB, VE, V5, 15 and 25. These assemblies consist of nested slug columns with individual uranium slugs cladded in aluminum cans. The CREDIT code was modified to calculate the oxide film thickness and the aluminum-oxide temperature at each axial increment. This information in this report will be used to evaluate the potential for cladding corrosion of the Mark 25 assembly

  20. Beyond δ : Tailoring marked statistics to reveal modified gravity

    Science.gov (United States)

    Valogiannis, Georgios; Bean, Rachel

    2018-01-01

    Models that seek to explain cosmic acceleration through modifications to general relativity (GR) evade stringent Solar System constraints through a restoring, screening mechanism. Down-weighting the high-density, screened regions in favor of the low density, unscreened ones offers the potential to enhance the amount of information carried in such modified gravity models. In this work, we assess the performance of a new "marked" transformation and perform a systematic comparison with the clipping and logarithmic transformations, in the context of Λ CDM and the symmetron and f (R ) modified gravity models. Performance is measured in terms of the fractional boost in the Fisher information and the signal-to-noise ratio (SNR) for these models relative to the statistics derived from the standard density distribution. We find that all three statistics provide improved Fisher boosts over the basic density statistics. The model parameters for the marked and clipped transformation that best enhance signals and the Fisher boosts are determined. We also show that the mark is useful both as a Fourier and real-space transformation; a marked correlation function also enhances the SNR relative to the standard correlation function, and can on mildly nonlinear scales show a significant difference between the Λ CDM and the modified gravity models. Our results demonstrate how a series of simple analytical transformations could dramatically increase the predicted information extracted on deviations from GR, from large-scale surveys, and give the prospect for a much more feasible potential detection.

  1. Serviceable pavement marking retroreflectivity levels : technical report.

    Science.gov (United States)

    2009-03-01

    This research addressed an array of issues related to measuring pavement markings retroreflectivity, factors : related to pavement marking performance, subjective evaluation process, best practices for using mobile : retroreflectometers, sampling pav...

  2. 46 CFR 108.645 - Markings on lifesaving appliances.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Markings on lifesaving appliances. 108.645 Section 108.645 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Equipment Markings and Instructions § 108.645 Markings on lifesaving appliances. (a...

  3. 25 CFR 141.16 - Price marking.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Price marking. 141.16 Section 141.16 Indians BUREAU OF... AND ZUNI RESERVATIONS General Business Practices § 141.16 Price marking. The price of each article... visible to the customer and that affords the customer a reasonable opportunity to learn the price of the...

  4. Marked colour divergence in the gliding membranes of a tropical lizard mirrors population differences in the colour of falling leaves.

    Science.gov (United States)

    Klomp, D A; Stuart-Fox, D; Das, I; Ord, T J

    2014-12-01

    Populations of the Bornean gliding lizard, Draco cornutus, differ markedly in the colour of their gliding membranes. They also differ in local vegetation type (mangrove forest versus lowland rainforest) and consequently, the colour of falling leaves (red and brown/black in mangrove versus green, brown and black in rainforest). We show that the gliding membranes of these lizards closely match the colours of freshly fallen leaves in the local habitat as they appear to the visual system of birds (their probable predators). Furthermore, gliding membranes more closely resembled colours of local fallen leaves than standing foliage or fallen leaves in the other population's habitat. This suggests that the two populations have diverged in gliding membrane coloration to match the colours of their local falling leaves, and that mimicking falling leaves is an adaptation that functions to reduce predation by birds. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  5. Scent-marking by coyotes, Canis latrans: the influence of social and ecological factors

    Science.gov (United States)

    Gese; Ruff

    1997-11-01

    We observed 49 coyotes, Canis latransfrom five resident packs for 2456 h and five transient coyotes for 51 h from January 1991 to June 1993 in the Lamar River Valley, Yellowstone National Park, Wyoming, U.S.A. During these observations we recorded 3042 urinations, 451 defecations, 446 ground scratches and 743 double-marks. The rate of scent-marking (via urination) was influenced by the social organization (resident versus transient) to which the coyote belonged, the social class (alpha, beta or pup) of the animal and the time of the year. Transient coyotes scent-marked at a lower rate than did members of a resident pack. Within the resident packs, alpha coyotes scent-marked at a higher rate than beta coyotes (adults and yearlings subordinant to alphas, but dominant over pups) and pups. Alpha coyotes increased their rate of marking during the breeding season; beta and pup coyotes performed scent-marks at a relatively constant rate throughout the year. There was no influence of social class or time of year on the rate of defecation. The rate of double-marking was highest among alpha coyotes with a peak during the breeding season. Alpha coyotes ground-scratched at a higher rate than did beta and pup coyotes. Alpha and beta coyotes scent-marked more than expected along the periphery of the territory compared to the interior; pups marked in the interior and edge in proportion to expected frequencies. Double-marking and ground-scratching were higher than expected along the periphery of the territory. The distribution of defecations was not different from expected along the edge versus the interior of the territory. Pack size did not influence the rate of scent-marking performed by individuals in the pack or by the alpha pair. We concluded that alpha coyotes were the primary members of the resident pack involved in scent-marking. The large coyote packs and the high rate of marking by the alpha pairs were parallel to the scent-marking behaviour displayed by wolves, C

  6. Is Wikipedia link structure different?

    NARCIS (Netherlands)

    Kamps, J.; Koolen, M.; Baeza-Yates, R.; Boldi, P.; Ribeiro-Neto, B.; Cambazoglu, B.B.

    2010-01-01

    In this paper, we investigate the difference between Wikipedia and Web link structure with respect to their value as indicators of the relevance of a page for a given topic of request. Our experimental evidence is from two IR test-collections: the .GOV collection used at the TREC Web tracks and the

  7. Structural and functional correlates of epileptogenesis — Does gender matter?

    Science.gov (United States)

    Savic, Ivanka; Engel, Jerome

    2016-01-01

    In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy. PMID:24943053

  8. 46 CFR 199.176 - Markings on lifesaving appliances.

    Science.gov (United States)

    2010-10-01

    ... ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Requirements for All Vessels § 199.176 Markings on lifesaving appliances. (a) Lifeboats and rescue boats. Each lifeboat and rescue boat must be plainly marked as follows: (1) Each side of each lifeboat and rescue boat bow must be marked in block...

  9. PREOPERATIVE ENDOSCOPIC MARKING OF UNPALPABLE COLONIC TUMORS

    Directory of Open Access Journals (Sweden)

    A. L. Goncharov

    2013-01-01

    Full Text Available The identification of small colon lesions is one of the major problems in laparoscopic colonic resection.Research objective: to develop a technique of visualization of small tumors of a colon by preoperative endoscopic marking of a tumor.Materials and methods. In one day prior to operation to the patient after bowel preparation the colonoscopy is carried out. In the planned point near tumor on antimesentery edge the submucous infiltration of marking solution (Micky Sharpz blue tattoo pigment, UK is made. The volume of entered solution of 1–3 ml. In only 5 months of use of a technique preoperative marking to 14 patients with small (the size of 1–3 cm malignant tumors of the left colon is performed.Results. The tattoo mark was well visualized by during operation at 13 of 14 patients. In all cases we recorded no complications. Time of operation with preoperative marking averaged 108 min, that is significantly less in comparison with average time of operation with an intra-operative colonoscopy – 155 min (р < 0.001.Conclusions. The first experience of preoperative endoscopic marking of non palpable small tumors of a colon is encouraging. Performance of a technique wasn't accompanied by complications and allowed to reduce significantly time of operation and to simplify conditions of performance of operation.

  10. 49 CFR 1520.13 - Marking SSI.

    Science.gov (United States)

    2010-10-01

    ... SECURITY INFORMATION § 1520.13 Marking SSI. (a) Marking of paper records. In the case of paper records... back cover, including a binder cover or folder, if the document has a front and back cover; (2) Any.... 552 and 49 CFR parts 15 and 1520. (d) Other types of records. In the case of non-paper records that...

  11. 9 CFR 316.13 - Marking of outside containers.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of outside containers. 316.13... INSPECTION AND CERTIFICATION MARKING PRODUCTS AND THEIR CONTAINERS § 316.13 Marking of outside containers. (a... domestic commerce is moved from an official establishment, the outside container shall bear an official...

  12. Forensic surface metrology: tool mark evidence.

    Science.gov (United States)

    Gambino, Carol; McLaughlin, Patrick; Kuo, Loretta; Kammerman, Frani; Shenkin, Peter; Diaczuk, Peter; Petraco, Nicholas; Hamby, James; Petraco, Nicholas D K

    2011-01-01

    Over the last several decades, forensic examiners of impression evidence have come under scrutiny in the courtroom due to analysis methods that rely heavily on subjective morphological comparisons. Currently, there is no universally accepted system that generates numerical data to independently corroborate visual comparisons. Our research attempts to develop such a system for tool mark evidence, proposing a methodology that objectively evaluates the association of striated tool marks with the tools that generated them. In our study, 58 primer shear marks on 9 mm cartridge cases, fired from four Glock model 19 pistols, were collected using high-resolution white light confocal microscopy. The resulting three-dimensional surface topographies were filtered to extract all "waviness surfaces"-the essential "line" information that firearm and tool mark examiners view under a microscope. Extracted waviness profiles were processed with principal component analysis (PCA) for dimension reduction. Support vector machines (SVM) were used to make the profile-gun associations, and conformal prediction theory (CPT) for establishing confidence levels. At the 95% confidence level, CPT coupled with PCA-SVM yielded an empirical error rate of 3.5%. Complementary, bootstrap-based computations for estimated error rates were 0%, indicating that the error rate for the algorithmic procedure is likely to remain low on larger data sets. Finally, suggestions are made for practical courtroom application of CPT for assigning levels of confidence to SVM identifications of tool marks recorded with confocal microscopy. Copyright © 2011 Wiley Periodicals, Inc.

  13. Microscopic saw mark analysis: an empirical approach.

    Science.gov (United States)

    Love, Jennifer C; Derrick, Sharon M; Wiersema, Jason M; Peters, Charles

    2015-01-01

    Microscopic saw mark analysis is a well published and generally accepted qualitative analytical method. However, little research has focused on identifying and mitigating potential sources of error associated with the method. The presented study proposes the use of classification trees and random forest classifiers as an optimal, statistically sound approach to mitigate the potential for error of variability and outcome error in microscopic saw mark analysis. The statistical model was applied to 58 experimental saw marks created with four types of saws. The saw marks were made in fresh human femurs obtained through anatomical gift and were analyzed using a Keyence digital microscope. The statistical approach weighed the variables based on discriminatory value and produced decision trees with an associated outcome error rate of 8.62-17.82%. © 2014 American Academy of Forensic Sciences.

  14. Examining Differences in Within- and Between-Person Simple Structures of an Engineering Qualification Test Using Multilevel MIMIC Structural Equation Modeling

    Directory of Open Access Journals (Sweden)

    Ioannis Tsaousis

    2018-02-01

    Full Text Available The current study sought to meet three aims: (a to understand the optimal factor structure of the Professional Engineering (ProfEng test, a measure aiming to assess competency in engineering, within a multilevel (nested perspective; (b to examine the psychometric measurement invariance of the ProfEng test across levels due to nesting and across gender at the person level, and, (c to examine the internal consistency of the engineering competency measure at both levels in the analysis. Data involved 1,696 individuals across 21 universities who took a national licensure test as part of the professional accreditation process to obtain a work permit and practice the engineering profession in the Kingdom of Saudi Arabia. Data were analyzed by use of Multilevel Structural Equation Modeling (MLSEM. Results indicated that a 2-factor model at both levels of analysis provided the best fit to the data. We also examined violation of measurement invariance across clusters (cluster bias. Results showed that all factor loadings were invariant across levels, suggesting the presence of strong measurement invariance. Last, invariance across gender was tested by use of the MIMIC multilevel model. Results pointed to the existence of significant differences between genders on levels of personal and professional skills with females having higher levels on personal skills and males on professional. Estimates of internal consistency reliability also varied markedly due to nesting. It is concluded that ignoring a multilevel structure is associated with errors and inaccuracies in the measurement of person abilities as both measurement wise and precision wise the multilevel model provides increased accuracy at each level in the analysis.

  15. Bite marks on skin and clay: A comparative analysis

    Directory of Open Access Journals (Sweden)

    R.K. Gorea

    2014-12-01

    Full Text Available Bite marks are always unique because teeth are distinctive. Bite marks are often observed at the crime scene in sexual and in physical assault cases on the skin of the victims and sometimes on edible leftovers in burglary cases. This piece of evidence is often ignored, but if properly harvested and investigated, bite marks may prove useful in apprehending and successfully prosecuting the criminals. Due to the importance of bite marks, we conducted a progressive randomised experimental study conducted on volunteers. A total of 188 bite marks on clay were studied. Based on these findings, 93.34% of the volunteers could be identified from the bite marks on the clay. In addition, 201 impressions on skin were studied, and out of these cases, 41.01% of the same volunteers could be identified based on the bite mark impressions on the skin.

  16. Large Marks-decahedral Pd nanoparticles synthesized by a modified hydrothermal method using a homogeneous reactor

    International Nuclear Information System (INIS)

    Zhao, Haiqiang; Qi, Weihong; Ji, Wenhai; Wang, Tianran; Peng, Hongcheng; Wang, Qi; Jia, Yanlin; He, Jieting

    2017-01-01

    Fivefold symmetry appears only in small particles and quasicrystals because internal stress in the particles increases with the particle size. However, a typical Marks decahedron with five re-entrant grooves located at the ends of the twin boundaries can further reduce the strain energy. During hydrothermal synthesis, it is difficult to stir the reaction solution contained in a digestion high-pressure tank because of the relatively small size and high-temperature and high-pressure sealed environment. In this work, we optimized a hydrothermal reaction system by replacing the conventional drying oven with a homogeneous reactor to shift the original static reaction solution into a full mixing state. Large Marks-decahedral Pd nanoparticles (~90 nm) have been successfully synthesized in the optimized hydrothermal synthesis system. Additionally, in the products, round Marks-decahedral Pd particles were also found for the first time. While it remains a challenge to understand the growth mechanism of the fivefold twinned structure, we proposed a plausible growth-mediated mechanism for Marks-decahedral Pd nanoparticles based on observations of the synthesis process.

  17. Large Marks-decahedral Pd nanoparticles synthesized by a modified hydrothermal method using a homogeneous reactor

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haiqiang; Qi, Weihong, E-mail: qiwh216@csu.edu.cn; Ji, Wenhai; Wang, Tianran; Peng, Hongcheng; Wang, Qi; Jia, Yanlin; He, Jieting [Central South University, School of Materials Science and Engineering (China)

    2017-05-15

    Fivefold symmetry appears only in small particles and quasicrystals because internal stress in the particles increases with the particle size. However, a typical Marks decahedron with five re-entrant grooves located at the ends of the twin boundaries can further reduce the strain energy. During hydrothermal synthesis, it is difficult to stir the reaction solution contained in a digestion high-pressure tank because of the relatively small size and high-temperature and high-pressure sealed environment. In this work, we optimized a hydrothermal reaction system by replacing the conventional drying oven with a homogeneous reactor to shift the original static reaction solution into a full mixing state. Large Marks-decahedral Pd nanoparticles (~90 nm) have been successfully synthesized in the optimized hydrothermal synthesis system. Additionally, in the products, round Marks-decahedral Pd particles were also found for the first time. While it remains a challenge to understand the growth mechanism of the fivefold twinned structure, we proposed a plausible growth-mediated mechanism for Marks-decahedral Pd nanoparticles based on observations of the synthesis process.

  18. Structural insights into the regulation and the recognition of histone marks by the SET domain of NSD1

    International Nuclear Information System (INIS)

    Morishita, Masayo; Di Luccio, Eric

    2011-01-01

    Highlights: → NSD1, NSD2/MMSET/WHSC1, and NSD3/WHSC1L1 are histone methyltransferases linked to numerous cancers. → Little is known about the NSD pathways and HMTase inhibitors are sorely needed in the epigenetic therapy of cancers. → We investigate the regulation and the recognition of histone marks by the SET domain of NSD1. → A unique and key mechanism is driven by a loop at the interface of the SET and postSET region. → Implications for developing specific and selective HMTase inhibitors are presented. -- Abstract: The development of epigenetic therapies fuels cancer hope. DNA-methylation inhibitors, histone-deacetylase and histone-methyltransferase (HMTase) inhibitors are being developed as the utilization of epigenetic targets is emerging as an effective and valuable approach to chemotherapy as well as chemoprevention of cancer. The nuclear receptor binding SET domain (NSD) protein is a family of three HMTases, NSD1, NSD2/MMSET/WHSC1, and NSD3/WHSC1L1 that are critical in maintaining the chromatin integrity. A growing number of studies have reported alterations or amplifications of NSD1, NSD2, or NSD3 in numerous carcinogenic events. Reducing NSDs activity through specific lysine-HMTase inhibitors appears promising to help suppressing cancer growth. However, little is known about the NSD pathways and our understanding of the histone lysine-HMTase mechanism is partial. To shed some light on both the recognition and the regulation of epigenetic marks by the SET domain of the NSD family, we investigate the structural mechanisms of the docking of the histone-H4 tail on the SET domain of NSD1. Our finding exposes a key regulatory and recognition mechanism driven by the flexibility of a loop at the interface of the SET and postSET region. Finally, we prospect the special value of this regulatory region for developing specific and selective NSD inhibitors for the epigenetic therapy of cancers.

  19. 49 CFR 172.317 - KEEP AWAY FROM HEAT handling mark.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false KEEP AWAY FROM HEAT handling mark. 172.317 Section... REQUIREMENTS, AND SECURITY PLANS Marking § 172.317 KEEP AWAY FROM HEAT handling mark. (a) General. For... of Division 5.2 must be marked with the KEEP AWAY FROM HEAT handling mark specified in this section...

  20. Configurational Model for Conductivity of Stabilized Fluorite Structure Oxides

    DEFF Research Database (Denmark)

    Poulsen, Finn Willy

    1981-01-01

    The formalism developed here furnishes means by which ionic configurations, solid solution limits, and conductivity mechanisms in doped fluorite structures can be described. The present model differs markedly from previous models but reproduces qualitatively reality. The analysis reported...

  1. TRANSITION METAL OXIDES AS MATERIALS FOR ADDITIVE LASER MARKING ON STAINLESS STEEL

    Directory of Open Access Journals (Sweden)

    Mihail Stoyanov Mihalev

    2017-09-01

    Full Text Available The product information plays an important role in the improvement of the manufacturing, allowing the tracking of the part through the full life cycle. Laser marking is one of the most versatile techniques for this purpose. In this paper, a modification of the powder bed selective laser melting for additive laser marking of stainless steel parts is presented. This modification is based on the use of only one transition metal oxide chemically bonded to the stainless steel substrate, without using any additional materials and cleaning substances. The resulting additive coatings, produced from initial MoO3 and WO3 powders, show strong adhesion, high hardness, long durability and a high optical contrast. For estimation of the chemical and structural properties, the Raman and X-Ray Diffraction (XRD spectroscopy have been implemented. A computer model of the process of the laser melting and re-solidification has been developed as well. A comparative analysis of the properties of both (MoO3 and WO3 additive coatings has been performed. An attempt for a qualitative explanation of the thermo-chemical phenomena during the marking process has been undertaken.

  2. Mark Raidpere portreefotod Kielis

    Index Scriptorium Estoniae

    1999-01-01

    Kieli Linnagaleriis avatud 2. Ars Baltica fototriennaalil 'Can You Hear Me?' esindab Eestit Mark Raidpere seeriaga 'Portreed 1998'. Näituse Eesti-poolne kuraator Anu Liivak, kataloogiteksti kirjutas Anders Härm. Tuntumaid osalejaid triennaalil Wolfgang Tillmans

  3. Mark 1 Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

  4. Muzzle imprint mark: a patterned injury which may be constituted of intradermal blood extravasations.

    Science.gov (United States)

    Pircher, R; Bielefeld, L; Geisenberger, D; Große Perdekamp, M; Pollak, S; Thierauf-Emberger, A

    2014-11-01

    The muzzle imprint mark in contact shots is usually regarded as a patterned pressure abrasion depicting the barrel end as well as adjacent constructional components of the weapon. Due to parching after exposure to air, the affected skin assumes a brown color, especially along the contours of the impacting structures. Apart from this well-known type of epidermal damage, the imprint mark may also be formed by intradermal hemorrhages. In some cases, these intracutaneous bleedings manifest themselves as circular, curved or straight reddish lines mirroring the surface relief of the weapon's muzzle end. To estimate the frequency of skin hematomas in muzzle imprints, 35 consecutive contact shots to the head (temple, forehead, submental and occipital region) were evaluated. In 3 cases, the muzzle imprint mark exclusively consisted of intracutaneous bruises surrounding the bullet entrance hole. In 14 cases, the muzzle imprint was composed of both excoriations and intradermal hematomas. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Mark Raidpere näitused Pariisis ja Napolis / Mark Raidpere ; interv. Harry Liivrand

    Index Scriptorium Estoniae

    Raidpere, Mark

    2008-01-01

    Mark Raidpere videod "Vekovka", "Dedication / Pühendus", "Majestoso Mystico" näitusel Pariisis Michel Reini galeriis. Osaleb koos saksa fotograafi Sven Johnega näitusel Napolis. Kreekas Thessalonikis valminud filmist "1:1:1"

  6. Study on core flow distribution of the reference core design Mark-III of experimental multi-purpose VHTR

    International Nuclear Information System (INIS)

    Satoh, Sadao; Arai, Taketoshi; Miyamoto, Yoshiaki; Hirano, Mitsumasa

    1977-01-01

    Concerning the coolant flow distribution between fuel channels and other flow paths in the core, designated as Reference Core Mark-III of the Multi-purpose Experimental Very High Temperature Reactor, thermal analysis has been made of the control rods and other steel structures around the core to find the coolant flow rates (bypass flow) necessary to cool them to their safe operating temperatures. Calculations showed that adequate cooling could be achieved in the Mark-III Core by the bypass flow of 8% of the total reactor coolant flow, 4% each for the control-rod channels and for other structures. The thermal and coolant flow design bases, including the assumption of a 10% bypass flow, were thus confirmed to first approximation. (auth.)

  7. Transgenerational isotopic marking of carp Cyprinus carpio, L. using a 86Sr /84Sr double spike

    Science.gov (United States)

    Zitek, Andreas; Cervicek, Magdalena; Irrgeher, Johanna; Horsky, Monika; Kletzl, Manfred; Weismann, Thomas; Prohaska, Thomas

    2013-04-01

    Transgenerational isotopic marking has been recognized recently as an effective tool for mass marking and tracking of individual fish to their original source. Compared to other conventional marking techniques, transgenerational marking offers several advantages. Most importantly, it is possible to mark all offspring of one individual female without the necessity of handling eggs or larval fish. Furthermore it is possible to vary the concentrations of individual isotopes to obtain specific marks for individual female fish. An enriched isotopic spike solution is usually applied to gravid female spawners by injection into the body cavity for transgenerational marking. The isotope is then incorporated into the central otolith region of the offspring which is known to be built up by maternally derived material. Within this study transgenerational marking of a typical cyprinid fish species, Cyprinus carpio, L., was tested using a 86Sr /84Sr double spike. Buffered solutions with different isotopic composition and concentrations were administered to 4 female individuals by intraperitoneal injection 5 days before spawning, while one female was injected a blank solution. After spawning, otoliths (Lapilli) from juvenile fish were sampled at the age of about 5 months at fish sizes between 3 and 4 cm and analyzed for their isotopic composition by LA-ICPMS applying cross sectional line scans. Central otolith regions of the progeny showed a shift in the natural isotope ratios for the administered isotopes. Deconvolution of the blank corrected measurement data of the Sr isotopes was done to trace back the original spike ratio. The different spike ratios could be well distinguished reflecting the original composition of the spike solution. This study proved that it is possible to create batch-specific unique transgenerational marks in otolith cores by varying the concentrations of two naturally occurring Sr isotopes. This method has high potential to reduce the marking effort for

  8. Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle.

    Science.gov (United States)

    Horcajo, P; Xia, D; Randle, N; Collantes-Fernández, E; Wastling, J; Ortega-Mora, L M; Regidor-Cerrillo, J

    2017-11-14

    Neospora caninum is one of the main causes of transmissible abortion in cattle. Intraspecific variations in virulence have been widely shown among N. caninum isolates. However, the molecular basis governing such variability have not been elucidated to date. In this study label free LC-MS/MS was used to investigate proteome differences between the high virulence isolate Nc-Spain7 and the low virulence isolate Nc-Spain1H throughout the tachyzoite lytic cycle. The results showed greater differences in the abundance of proteins at invasion and egress with 77 and 62 proteins, respectively. During parasite replication, only 19 proteins were differentially abundant between isolates. The microneme protein repertoire involved in parasite invasion and egress was more abundant in the Nc-Spain1H isolate, which displays a lower invasion rate. Rhoptry and dense granule proteins, proteins related to metabolism and stress responses also showed differential abundances between isolates. Comparative RNA-Seq analyses during tachyzoite egress were also performed, revealing an expression profile of genes associated with the bradyzoite stage in the low virulence Nc-Spain1H isolate. The differences in proteome and RNA expression profiles between these two isolates reveal interesting insights into likely mechanisms involved in specific phenotypic traits and virulence in N. caninum. The molecular basis that governs biological variability in N. caninum and the pathogenesis of neosporosis has not been well-established yet. This is the first study in which high throughput technology of LC-MS/MS and RNA-Seq is used to investigate differences in the proteome and transcriptome between two well-characterized isolates. Both isolates displayed different proteomes throughout the lytic cycle and the transcriptomes also showed marked variations but were inconsistent with the proteome results. However, both datasets identified a pre-bradyzoite status of the low virulence isolate Nc-Spain1H. This study

  9. Burn-up TRIGA Mark II benchmark experiment

    International Nuclear Information System (INIS)

    Persic, A.; Ravnik, M.; Zagar, T.

    1998-01-01

    Different reactor codes are used for calculations of reactor parameters. The accuracy of the programs is tested through comparison of the calculated values with the experimental results. Well-defined and accurately measured benchmarks are required. The experimental results of reactivity measurements, fuel element reactivity worth distribution and fuel-up measurements are presented in this paper. The experiments were performed with partly burnt reactor core. The experimental conditions were well defined, so that the results can be used as a burn-up benchmark test case for a TRIGA Mark II reactor calculations.(author)

  10. EcoMark 2.0

    DEFF Research Database (Denmark)

    Guo, Chenjuan; Yang, Bin; Andersen, Ove

    2015-01-01

    Eco-routing is a simple yet effective approach to substantially reducing the environmental impact, e.g., fuel consumption and greenhouse gas (GHG) emissions, of vehicular transportation. Eco-routing relies on the ability to reliably quantify the environmental impact of vehicles as they travel...... in a spatial network. The procedure of quantifying such vehicular impact for road segments of a spatial network is called eco-weight assignment. EcoMark 2.0 proposes a general framework for eco-weight assignment to enable eco-routing. It studies the abilities of six instantaneous and five aggregated models......, and experiments for assessing the utility of the impact models in assigning eco-weights. The application of EcoMark 2.0 indicates that the instantaneous model EMIT and the aggregated model SIDRA-Running are suitable for assigning eco-weights under varying circumstances. In contrast, other instantaneous models...

  11. Interview with Mark Watson

    Directory of Open Access Journals (Sweden)

    Katy Shaw

    2016-04-01

    Full Text Available Mark Watson is a British comedian and novelist. His five novels to date – 'Bullet Points' (2004, 'A Light-Hearted Look At Murder' (2007, 'Eleven' (2010, 'The Knot' (2012 and 'Hotel Alpha' (2014 – explore human relationships and communities in contemporary society. His latest novel Hotel Alpha tells the story of an extraordinary hotel in London and two mysterious disappearances that raise questions no one seems willing to answer. External to the novel, readers can also discover more about the hotel and its inhabitants in one hundred extra stories that expand the world of the novel and can be found at http://www.hotelalphastories.com. In conversation here with Dr Katy Shaw, Mark offers some reflections on his writing process, the field of contemporary literature, and the vitality of the novel form in the twenty-first century.

  12. Flow-induced vibration phenomenon in a Mark III TRIGA reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, C K; Whittemore, W L; Kim, B S; Lee, J B; Blevins, R D; Burton, T E [Korea Atomic Energy Research Institute, Seoul (Korea, Republic of); General Atomic Company, San Diego, CA (United States)

    1976-07-01

    The Mark III TRIGA reactor with hexagonal fuel spacing is capable of operating at 2.0 MW. The Mark III at San Diego operated without core cooling problems or vibration at power levels up to 2.0 MW. All Mark III reactors have operated trouble-free up to 1.0 MW. The Mark III TRIGA in Korea was installed in 1972 and operated many months without trouble at 2.0 MW. During this period core changes including addition of new fuel were made. Eighteen months after startup, a coolant flow-induced vibration was observed for the first time at a power of 1.5 MW. A lengthy series of tests showed that it was not possible to establish a core configuration that permitted vibration-free operation for power levels in the range 1.5 - 2.0 MW. Observations during the tests confirmed that standing waves in the reactor tank water coupled the source within the core to the shield structure and surrounding building. Analysis of the data indicates strongly that the source of the vibration is the creation and collapse of bubbles with the core acting as a resonator. A substantially increased flow of coolant through the upper grid plate is expected to eliminate the vibration phenomenon and permit trouble-free operation at power up to 2.0 MW. In an attempt to seek a remedy, both GAC and KAERI have independently developed designs for upper grid plates. KAERI has constructed and installed an interim version of the standard grid plate which was calculated to provide 25% more coolant flow and mounted high so as to provide less restriction to flow around the upper fittings of the fuel elements. A substantial reduction in vibration was observed. No vibration was observed at any power up to 2.0 MW with cooling water at or below 20 C. A slight vibration at 1.8 MW occurred for higher cooling temperatures. The GAC grid plate design provides not only for increasing the flow area but also for streamlining the flow surfaces on the grid plate and possibly also on the top fittings of the fuel elements. It is

  13. Flow-induced vibration phenomenon in a Mark III TRIGA reactor

    International Nuclear Information System (INIS)

    Lee, C.K.; Whittemore, W.L.; Kim, B.S.; Lee, J.B.; Blevins, R.D.; Burton, T.E.

    1976-01-01

    The Mark III TRIGA reactor with hexagonal fuel spacing is capable of operating at 2.0 MW. The Mark III at San Diego operated without core cooling problems or vibration at power levels up to 2.0 MW. All Mark III reactors have operated trouble-free up to 1.0 MW. The Mark III TRIGA in Korea was installed in 1972 and operated many months without trouble at 2.0 MW. During this period core changes including addition of new fuel were made. Eighteen months after startup, a coolant flow-induced vibration was observed for the first time at a power of 1.5 MW. A lengthy series of tests showed that it was not possible to establish a core configuration that permitted vibration-free operation for power levels in the range 1.5 - 2.0 MW. Observations during the tests confirmed that standing waves in the reactor tank water coupled the source within the core to the shield structure and surrounding building. Analysis of the data indicates strongly that the source of the vibration is the creation and collapse of bubbles with the core acting as a resonator. A substantially increased flow of coolant through the upper grid plate is expected to eliminate the vibration phenomenon and permit trouble-free operation at power up to 2.0 MW. In an attempt to seek a remedy, both GAC and KAERI have independently developed designs for upper grid plates. KAERI has constructed and installed an interim version of the standard grid plate which was calculated to provide 25% more coolant flow and mounted high so as to provide less restriction to flow around the upper fittings of the fuel elements. A substantial reduction in vibration was observed. No vibration was observed at any power up to 2.0 MW with cooling water at or below 20 C. A slight vibration at 1.8 MW occurred for higher cooling temperatures. The GAC grid plate design provides not only for increasing the flow area but also for streamlining the flow surfaces on the grid plate and possibly also on the top fittings of the fuel elements. It is

  14. Recognition in context: Implications for trade mark law.

    Science.gov (United States)

    Humphreys, Michael S; McFarlane, Kimberley A; Burt, Jennifer S; Kelly, Sarah J; Weatherall, Kimberlee G; Burrell, Robert G

    2017-10-01

    Context effects in recognition have played a major role in evaluating theories of recognition. Understanding how context impacts recognition is also important for making sound trade mark law. Consumers attempting to discriminate between the brand they are looking for and a look-alike product often have to differentiate products which share a great deal of common context: positioning on the supermarket shelf, the type of store, aspects of the packaging, or brand claims. Trade mark and related laws aim to protect brands and reduce consumer confusion, but courts assessing allegations of trade mark infringement often lack careful empirical evidence concerning the impact of brand and context similarity, and, in the absence of such evidence, make assumptions about how consumers respond to brands that downplay the importance of context and focus on the similarity of registered marks. The experiments reported in this paper aimed to test certain common assumptions in trade mark law, providing evidence that shared context can cause mistakes even where brand similarity is low.

  15. The effects of Web site structure: the role of personal difference.

    Science.gov (United States)

    Chung, Hwiman; Ahn, Euijin

    2007-12-01

    This study examined the effects of Web site structures in terms of advertising effectiveness- memory, attitude, and behavioral intentions. The primary research question for this study is, What type of Web site (Web ad) structure is most effective? In the pilot study, we tested the difference between two Web site structures, linear and interactive, in terms of traditional advertising effectiveness. Results from the pilot study did not support our research expectations. However, differences in terms of memory were noted between the two structures. After re-creating the Web site based on subjects' comments, in the final experiment, we examined the differences between the two structures and the moderating role of personality difference on the effects of Web site structure. The results confirm that participants' attitude, memory, and behavioral intentions were affected differently by the different Web site structures. However, some research hypotheses were not supported by the current data.

  16. Trade Mark Cluttering: An Exploratory Report Commissioned by UKIPO

    OpenAIRE

    von Graevenitz, Georg; Greenhalgh, Christine; Helmers, Christian; Schautschick, Philipp

    2012-01-01

    This report explores the problem of “cluttering” of trade mark registers. The report consists of two parts: the first presents a conceptual discussion of “cluttering” of trade mark registers. The second part provides an exploratory empirical analysis of trade mark applications at the UK Intellectual Property Office (UKIPO) and the European trade mark office (OHIM). This part contains results of a descriptive and an econometric analysis. According to our definition, cluttering arises where fir...

  17. 32 CFR 2400.16 - Derivative classification markings.

    Science.gov (United States)

    2010-07-01

    ... SECURITY PROGRAM Derivative Classification § 2400.16 Derivative classification markings. (a) Documents... 32 National Defense 6 2010-07-01 2010-07-01 false Derivative classification markings. 2400.16..., as described in § 2400.12 of this part, the information may not be used as a basis for derivative...

  18. Applying a uniform marked morphism to a word

    Directory of Open Access Journals (Sweden)

    Anna Frid

    1999-12-01

    Full Text Available We describe the relationship between different parameters of the initial word and its image obtained by application of a uniform marked morphism. The functions described include the subword complexity, frequency of factors, and the recurrence function. The relations obtained for the image of a word can be used also for the image of a factorial language. Using induction, we give a full description of the involved functions of the fixed point of the morphism considered.

  19. Tooth-marked small theropod bone: an extremely rare trace

    DEFF Research Database (Denmark)

    Jacobsen, Aase Roland

    2001-01-01

    Tooth-marked dinosaur bones provide insight into feeding behaviours and biting strategies of theropod dinosaurs. The majority of theropod tooth marks reported to date have been found on herbivorous dinosaur bones, although some tyrannosaurid bones with tooth marks have also been reported. In 1988...

  20. Severe accident progression perspectives for Mark I containments based on the IPE results

    International Nuclear Information System (INIS)

    Lin, C.C.; Lehner, J.R.; Pratt, W.T.; Drouin, M.

    1995-01-01

    Based on level 2 analyses in IPE (Individual Plant Examination) submittals accident progression, perspectives were obtained for all containment types. These perspectives consisted of insights on containment failure modes, releases therein, and factors responsible for the results. To illustrate the types of perspectives acquired on severe accident progresssion, insights obtained for (BWR) Mark I containments are discussed here. Mark I containments have high strength but small volumes and rely on pressure suppression pools to condense steam released from the reactor coolant system during an accident. Accidents causing structural failure of the drywell shortly after the core debris melts through the reactor vessel were found to be dominant contributors to risk. Importance of individual containment failure mechanisms depends on plant features and in some cases on modeling assumptions; however the following mechanisms were found important: drywell shell melt-through caused by direct contact with core debris and drywell failure caused by rapid pressure/temperature pulses at time of vessel melt-through. Drywell failure caused by gradual pressure/temperature buildup due to gases and steam released during core/concrete interactions is important in some IPEs. In other IPEs vent was an important contributor. However, accidents that bypass containment (eg interfacing systems LOCA)or involve containment isolation failure were not important contributors to the CDF in any of the IPEs for Mark I plants. These accidents are also not important to risk (even though they can involve large fission product release) because their frequencies of occurrence are so much lower than frequencies of early structural failure caused by other accidents that dominate the CDF

  1. Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses.

    Science.gov (United States)

    Negro, S; Imsland, F; Valera, M; Molina, A; Solé, M; Andersson, L

    2017-06-01

    Several variants in the KIT, PAX3 and MITF genes have previously been associated with white markings in horses. In this study, we examined eight variants of these genes in 70 Menorca Purebred horses (PRMe, only black solid-coloured horses) and 70 Spanish Purebred horses (PRE, different coat colour patterns) that were scored for the extent of white markings. A maximum-likelihood chi-square test, logistic regression model and ridge regression analyses showed that a missense mutation (p.Arg682His) in KIT was associated with white facial markings (P horses. The relative contribution of this variant to white markings in PRMe horses was estimated at 47.6% (head) and 43.4% (total score). In PRE horses, this variant was also associated with hindlimb scores (P T intronic variant located 29.9 kb downstream from the transcription start site of the MITF gene was associated with less white markings on forelimbs (P horses, with a relative contribution of 63.9%, whereas in PRE horses this variant was associated with white facial markings (P horses, providing breeders with an opportunity to use genetic testing to aid in breeding for their desired level of white markings. © 2017 Stichting International Foundation for Animal Genetics.

  2. 7 CFR 920.303 - Container marking regulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container marking regulations. 920.303 Section 920.303... Miscellaneous Provisions § 920.303 Container marking regulations. No handler shall ship any kiwifruit except in accordance with the following terms and conditions: (a) Each package or container of kiwifruit shall bear on...

  3. Experiments in radioactive marking of lipopoly saccharides in the framework of endotoxin research

    International Nuclear Information System (INIS)

    Steinmueller, B.

    1985-01-01

    The endotoxin from E. coli was marked using Na-125-iodine, in order to eventually through animal experiments obtain more information about the biological attack site of the endotoxin in the organism. The endotoxin from S. equi served thereby as a reference substance, since more exact information about the structure and degree of purity of this endotoxin is present. (orig.) [de

  4. 27 CFR 19.612 - Authorized abbreviations to identify marks.

    Science.gov (United States)

    2010-04-01

    ... T Tax Determined TD Wine Spirits Addition WSA (Sec. 201, Pub. L. 85-859, 72 Stat. 1360, as amended... TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Containers and Marks... to identify certain marks: Mark Abbreviation Completely Denatured Alcohol CDA Distilled Spirits...

  5. Soil-gas phase transport and structure parameters for soils under different management regimes and at two moisture levels

    DEFF Research Database (Denmark)

    Eden, Marie; Møldrup, Per; Schjønning, Per

    2012-01-01

    Measurements of diffusive and convective gas transport parameters can be used to describe soil functional architecture and reveal key factors for soil structure development. Undisturbed 100-cm(3) soil samples were sampled at the Long-term Research on Agricultural Systems experiment located...... displayed markedly lower D-P/D-0 values at similar air-filled porosity, illustrating soil structure effects on D-P/D-0. The Currie tortuosity-connectivity parameter, X=Log(D-P/D-0)/Log(epsilon), decreased with increasing bulk density in the intact samples at both moisture conditions, suggesting less...

  6. 46 CFR 160.077-31 - PFD Marking.

    Science.gov (United States)

    2010-10-01

    ... Marking. (a) General. Each hybrid PFD must be marked with the applicable information required by this... text of special purpose or limitation and vessel(s) or vessel type(s), noted on approval certificate... and be presented in the exact order shown: Type [II, III, or V, as applicable] PFD [See paragraph (k...

  7. 9 CFR 590.418 - Supervision of marking and packaging.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging...) Identifying and Marking Product § 590.418 Supervision of marking and packaging. (a) Evidence of label approval... has on file evidence that such official identification or packaging material bearing such official...

  8. Background sources and masks for Mark II detector at PEP

    International Nuclear Information System (INIS)

    Kadyk, J.

    1981-06-01

    The shielding masks currently at use in several of the current experiments at PEP are the result of an early organized effort to understand the sources of particle background expected at PEP, followed by the evolution of the conceptual designs into actual hardware. The degree and kind of background particle loading which could be tolerated was expected to differ significantly among the different experiments, and several designs emerged from the common study. Qualitatively, the types of radiations studied were, Synchrotron Radiation (SR), Beam Gas Bremsstrahlung (BGB), and, to a limited extent others, e.g., Electroproduction (EP). Calculations will be given of predicted occupancies in the pipe counter and other sensitive elements at small radius, since these will be most susceptible to the SR and BGB backgrounds. The calculations presented in this note are specific to the Mark II detector. Some general statements will be made first about the character of each of the various types of backgrounds considered, then some detailed calculations made for application to the Mark II detector

  9. Lane marking detection based on waveform analysis and CNN

    Science.gov (United States)

    Ye, Yang Yang; Chen, Hou Jin; Hao, Xiao Li

    2017-06-01

    Lane markings detection is a very important part of the ADAS to avoid traffic accidents. In order to obtain accurate lane markings, in this work, a novel and efficient algorithm is proposed, which analyses the waveform generated from the road image after inverse perspective mapping (IPM). The algorithm includes two main stages: the first stage uses an image preprocessing including a CNN to reduce the background and enhance the lane markings. The second stage obtains the waveform of the road image and analyzes the waveform to get lanes. The contribution of this work is that we introduce local and global features of the waveform to detect the lane markings. The results indicate the proposed method is robust in detecting and fitting the lane markings.

  10. UID...Leaving Its Mark on the Universe

    Science.gov (United States)

    Schramm, Harry F., Jr.

    2008-01-01

    Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21 st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture, recently trademarked as Nanocodes, that can be converted to Data Matrix information through software. The accompanying intellectual property is protected by ten patents, several of which are licensed. Direct marking Data Matrix on NASA parts dramatically decreases data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection.

  11. UID....Now That's Gonna Leave A Mark

    Science.gov (United States)

    Schramm, Harry F., Jr.

    2008-01-01

    Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21 st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture, recently trademarked as Nanocodes, that can be converted to Data Matrix information through software. The accompanying intellectual property is protected by ten patents, several of which are licensed. Direct marking Data Matrix on NASA parts dramatically decreases data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection.

  12. Otolith marking of juvenile shortnose gar by immersion in oxytetracycline

    Science.gov (United States)

    Snow, Richard A.; Long, James M.

    2017-01-01

    Oxytetracycline (OTC) has been used to mark a variety of fish species at multiple developmental stages; however, there is little information on batch-marking Lepisosteidae. Juvenile Shortnose Gar Lepisosteus platostomus (53 ± 3 mm TL) were seined from an Oklahoma State University research pond and transported to the Oklahoma Fishery Research Lab. Juvenile Shortnose Gar were exposed to a range of OTC concentrations—0, 500, 600, and 700 mg/L—for 4, 5, or 6 h. Lapillus and sagitta otoliths were examined 14 d postexposure for mark presence and evaluation using fluorescent microscopy. Overall, 93.3% of otoliths exposed to OTC exhibited a mark. Concentration of OTC affected the mean mark quality, whereas duration and otolith type examined did not. However, as concentration increased, so did mortality, suggesting a balance is needed to achieve marking goals. Based on our findings, batch marking of Shortnose Gar can be successful at OTC concentrations from 500 to 700 mg/L for 4–6 h, although mark quality may vary and mortality rates increase at the higher concentrations and longer durations.

  13. Validation of a multi-frequency electrical impedance tomography (mfEIT) system KHU Mark1: impedance spectroscopy and time-difference imaging

    International Nuclear Information System (INIS)

    Oh, Tong In; Koo, Hwan; Lee, Kyung Heon; Kim, Sang Min; Woo, Eung Je; Lee, Jeehyun; Kim, Sung Wan; Seo, Jin Keun

    2008-01-01

    Validation and interpretation of reconstructed images using a multi-frequency electrical impedance tomography (mfEIT) requires a conductivity phantom including imaging objects with known complex conductivity (σ + iωε) spectra. We describe imaging experiments using the recently developed mfEIT system called the KHU Mark1 with the frequency range of 10 Hz to 500 kHz. Using a bio-impedance spectroscopy (BIS) system, we first measured complex conductivity spectra of different imaging objects including saline, agar, polyacrylamide, TX151, animal hide gelatin, banana and cucumber. Based on an analysis of how conductivity and permittivity affect measured complex boundary voltages, we suggested a new complex version of a multi-frequency time-difference image reconstruction algorithm. Imaging experiments were conducted to produce time-difference images of the objects at multiple frequencies using the proposed algorithm. Images of a conductor (stainless steel) and an insulator (acrylic plastic) were used to set a common scale bar to display all images. Comparing reconstructed time-difference images at multiple frequencies with measured complex conductivity spectra, we found that they showed an overall similarity in terms of changes in complex conductivity values with respect to frequency. However, primarily due to the limitation of the difference imaging algorithm, we suggest that multi-frequency time-difference images must be interpreted in terms of relative contrast changes with respect to frequency. We propose further imaging studies using biological tissues of known complex conductivity spectra and using human subjects to find clinical applications of the mfEIT system

  14. Book Review: "Educational Reform and Administrative Development: The Cases of Columbia and Venezuela," by E. Mark Hanson.

    Science.gov (United States)

    Lynch, Patrick D.

    1988-01-01

    Reviews "Educational Reform and Administrative Development: The Cases of Colombia and Venezuela," by E. Mark Hanson, which relates the policy-making and administrative structures of these two countries to their political, historical, and cultural contexts. (TE)

  15. Electromagnetic and structural interaction analysis of curved shell structures

    International Nuclear Information System (INIS)

    Horie, T.; Niho, T.

    1993-01-01

    This paper describes a finite element formulation of the eddy current and structure coupled problem for curved shell structures. Coupling terms produced by curved geometry as well as flat plate geometry were obtained. Both matrix equations for eddy current and structure were solved simultaneously using coupling sub-matrices. TEAM Workshop bench mark problem 16 was solved to verify the formulation and the computer code. Agreement with experimental results was very good for such plate problem. A coupled problem for cylindrical shell structure was also analyzed. Influence of each coupling term was examined. The next topic is the eigenvalues of the coupled equations. Although the coupled matrix equations are not symmetric, symmetry was obtained by introducing a symmetrizing variable. The eigenvalues of the coupled matrix equations are different from those obtained from the uncoupled equations because of the influence of the coupling sub-matrix components. Some parameters obtained by the eigenvalue analysis have characteristics of parameters which indicate the intensity of electromagnetic structural coupling effect. (author)

  16. Mark-recapture using tetracycline and genetics reveal record-high bear density

    Science.gov (United States)

    Peacock, E.; Titus, K.; Garshelis, D.L.; Peacock, M.M.; Kuc, M.

    2011-01-01

    We used tetracycline biomarking, augmented with genetic methods to estimate the size of an American black bear (Ursus americanus) population on an island in Southeast Alaska. We marked 132 and 189 bears that consumed remote, tetracycline-laced baits in 2 different years, respectively, and observed 39 marks in 692 bone samples subsequently collected from hunters. We genetically analyzed hair samples from bait sites to determine the sex of marked bears, facilitating derivation of sex-specific population estimates. We obtained harvest samples from beyond the study area to correct for emigration. We estimated a density of 155 independent bears/100 km2, which is equivalent to the highest recorded for this species. This high density appears to be maintained by abundant, accessible natural food. Our population estimate (approx. 1,000 bears) could be used as a baseline and to set hunting quotas. The refined biomarking method for abundance estimation is a useful alternative where physical captures or DNA-based estimates are precluded by cost or logistics. Copyright ?? 2011 The Wildlife Society.

  17. Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention

    DEFF Research Database (Denmark)

    Meur, Gargi; Simon, Albane; Harun, Nasret

    2009-01-01

    OBJECTIVE: Heterozygous mutations in the human preproinsulin (INS) gene are a cause of nonsyndromic neonatal or early-infancy diabetes. Here, we sought to identify INS mutations associated with maturity-onset diabetes of the young (MODY) or nonautoimmune diabetes in mid-adult life, and to explore...... the molecular mechanisms involved. RESEARCH DESIGN AND METHODS: The INS gene was sequenced in 16 French probands with unexplained MODY, 95 patients with nonautoimmune early-onset diabetes (diagnosed at ... with early-onset diabetes whose clinical presentation is compatible with MODY. These led to the production of (pre)proinsulin molecules with markedly different trafficking properties and effects on ER stress, demonstrating a range of molecular defects in the beta-cell....

  18. Field manual for identifying and preserving high-water mark data

    Science.gov (United States)

    Feaster, Toby D.; Koenig, Todd A.

    2017-09-26

    This field manual provides general guidance for identifying and collecting high-water marks and is meant to be used by field personnel as a quick reference. The field manual describes purposes for collecting and documenting high-water marks along with the most common types of high-water marks. The manual provides a list of suggested field equipment, describes rules of thumb and best practices for finding high-water marks, and describes the importance of evaluating each high-water mark and assigning a numeric uncertainty value as part of the flagging process. The manual also includes an appendix of photographs of a variety of high-water marks obtained from various U.S. Geological Survey field investigations along with general comments about the logic for the assigned uncertainty values.

  19. The Information Literacy of Survey Mark Hunting: A Dialogue

    Directory of Open Access Journals (Sweden)

    Jennifer Galas

    2016-11-01

    Full Text Available In Brief: This article makes connections between the ACRL Framework for Information Literacy for Higher Education and the activity of survey mark hunting. After a brief review of the literature related to geographic information systems (GIS, information literacy, and gamification of learning, the authors enter into a dialogue in which they discover and describe the various ways information literacy is both required by and developed through the recreational activity of survey mark hunting. Through their dialogue they found that the activity of survey mark hunting relies on the construction of both information and its authority in ways contextualized within the communities that participate; that survey mark hunting is a conversation that builds on the past, where lived experience counts as evidence; and, that survey mark hunting is both a metaphor and embodied enactment of information literacy.

  20. Medical cautery units as a permanent and non-invasive method of marking lizards

    Directory of Open Access Journals (Sweden)

    Anna Ekner

    2011-12-01

    Full Text Available The identification of previously captured individuals is essential for a wide variety of ecological and behavioural studies. A lot of different methods are used for marking lizards, however they have many drawbacks. In presented study we used heat-branding method, using pen-like medical cautery units, previously employed to successfully mark other lizard species and snakes. The technique is permanent, readable and harmless for lizards, as well quick and easy. In 2009 we marked 111 individuals of sand lizard, Lacerta agilis. Next year we caught 88 lizards, 17 of them were re-captured. Among these re-captured lizards, five were caught after 26.8 (± 16.3 days (means in the same year and 12 after 308.8 (± 64.3 days (means in the next year. Recaptured individuals were still unambiguously recognisable.

  1. Intense structures of different momentum fluxes in turbulent channels

    Science.gov (United States)

    Osawa, Kosuke; Jiménez, Javier

    2018-04-01

    The effect of different definitions of the momentum flux on the properties of the coherent structures of the logarithmic region of wall-bounded turbulence is investigated by comparing the structures of intense tangential Reynolds stress with those of the alternative flux proposed in [Jimenez (2016) J. Fluid Mech. 809:585]. Despite the fairly different statistical properties of the two flux definitions, it is found that their intense structures show many similarities, such as the dominance of ‘wall-attached’ objects, and geometric self-similarity. However, the new structures are wider, although not taller, than the classical ones, and include both high- and low-momentum regions within the same object. It is concluded that they represent the same phenomenon as the classical group of a sweep, an ejection, and a roller, which should thus be considered as the fundamental coherent structure of the momentum flux. The present results suggest that the properties of these momentum structures are robust with respect to the definition of the fluxes.

  2. Mark Antony’s Homoeroticism in Cicero’s second Philippic

    Directory of Open Access Journals (Sweden)

    Bruna Fernanda Abreu

    2017-06-01

    Full Text Available Considering the concept of homosexuality in the ancient Rome, we attempt to analise how Cicero expose the Mark Antony’s “homosexuality” in his second Philippic. This speech is characterized by political and, mainly, personal accusations from Cicero to Mark Antony, and the Mark Antony’s passivity in his intercourses can be considered a topos of this invective speech.

  3. Factors correlating with significant differences between X-ray structures of myoglobin

    International Nuclear Information System (INIS)

    Rashin, Alexander A.; Domagalski, Marcin J.; Zimmermann, Michael T.; Minor, Wladek; Chruszcz, Maksymilian; Jernigan, Robert L.

    2014-01-01

    Conformational differences between myoglobin structures are studied. Most structural differences in whale myoglobin beyond the uncertainty threshold can be correlated with a few specific structural factors. There are always exceptions and a search for additional factors is needed. The results might have serious implications for biological insights from conformational differences. Validation of general ideas about the origins of conformational differences in proteins is critical in order to arrive at meaningful functional insights. Here, principal component analysis (PCA) and distance difference matrices are used to validate some such ideas about the conformational differences between 291 myoglobin structures from sperm whale, horse and pig. Almost all of the horse and pig structures form compact PCA clusters with only minor coordinate differences and outliers that are easily explained. The 222 whale structures form a few dense clusters with multiple outliers. A few whale outliers with a prominent distortion of the GH loop are very similar to the cluster of horse structures, which all have a similar GH-loop distortion apparently owing to intermolecular crystal lattice hydrogen bonds to the GH loop from residues near the distal histidine His64. The variations of the GH-loop coordinates in the whale structures are likely to be owing to the observed alternative intermolecular crystal lattice bond, with the change to the GH loop distorting bonds correlated with the binding of specific ‘unusual’ ligands. Such an alternative intermolecular bond is not observed in horse myoglobins, obliterating any correlation with the ligands. Intermolecular bonds do not usually cause significant coordinate differences and cannot be validated as their universal cause. Most of the native-like whale myoglobin structure outliers can be correlated with a few specific factors. However, these factors do not always lead to coordinate differences beyond the previously determined uncertainty

  4. Factors correlating with significant differences between X-ray structures of myoglobin

    Energy Technology Data Exchange (ETDEWEB)

    Rashin, Alexander A., E-mail: alexander-rashin@hotmail.com [BioChemComp Inc., 543 Sagamore Avenue, Teaneck, NJ 07666 (United States); Iowa State University, 112 Office and Lab Bldg, Ames, IA 50011-3020 (United States); Domagalski, Marcin J. [University of Virginia, 1340 Jefferson Park Avenue, Jordan Hall, Room 4223, Charlottesville, VA 22908 (United States); Zimmermann, Michael T. [Iowa State University, 112 Office and Lab Bldg, Ames, IA 50011-3020 (United States); Minor, Wladek [University of Virginia, 1340 Jefferson Park Avenue, Jordan Hall, Room 4223, Charlottesville, VA 22908 (United States); Chruszcz, Maksymilian [University of Virginia, 1340 Jefferson Park Avenue, Jordan Hall, Room 4223, Charlottesville, VA 22908 (United States); University of South Carolina, 631 Sumter Street, Columbia, SC 29208 (United States); Jernigan, Robert L. [Iowa State University, 112 Office and Lab Bldg, Ames, IA 50011-3020 (United States); BioChemComp Inc., 543 Sagamore Avenue, Teaneck, NJ 07666 (United States)

    2014-02-01

    Conformational differences between myoglobin structures are studied. Most structural differences in whale myoglobin beyond the uncertainty threshold can be correlated with a few specific structural factors. There are always exceptions and a search for additional factors is needed. The results might have serious implications for biological insights from conformational differences. Validation of general ideas about the origins of conformational differences in proteins is critical in order to arrive at meaningful functional insights. Here, principal component analysis (PCA) and distance difference matrices are used to validate some such ideas about the conformational differences between 291 myoglobin structures from sperm whale, horse and pig. Almost all of the horse and pig structures form compact PCA clusters with only minor coordinate differences and outliers that are easily explained. The 222 whale structures form a few dense clusters with multiple outliers. A few whale outliers with a prominent distortion of the GH loop are very similar to the cluster of horse structures, which all have a similar GH-loop distortion apparently owing to intermolecular crystal lattice hydrogen bonds to the GH loop from residues near the distal histidine His64. The variations of the GH-loop coordinates in the whale structures are likely to be owing to the observed alternative intermolecular crystal lattice bond, with the change to the GH loop distorting bonds correlated with the binding of specific ‘unusual’ ligands. Such an alternative intermolecular bond is not observed in horse myoglobins, obliterating any correlation with the ligands. Intermolecular bonds do not usually cause significant coordinate differences and cannot be validated as their universal cause. Most of the native-like whale myoglobin structure outliers can be correlated with a few specific factors. However, these factors do not always lead to coordinate differences beyond the previously determined uncertainty

  5. Recruitment in Swarm-Founding Wasps: Polybia occidentalis Does not Actively Scent-Mark Carbohydrate Food Sources

    Directory of Open Access Journals (Sweden)

    Benjamin J. Taylor

    2011-01-01

    Full Text Available Scent marking food resources is expected to enhance foraging efficiency reducing search time. Many social bees exhibit this behavior, but scent-marking is absent in social wasps, except for Vespa mandarinia. We tested for scent marking in the swarm-founding wasp, Polybia occidentalis. This wasp has moderately large colonies and utilizes resources that are concentrated in time and space, making scent marking profitable. Also, this wasp uses chemical markings to lead nestmates to a new nest site during swarm emigration, making it possible that it could use the same behavior to recruit nestmates to a food source. Foragers from 11 colonies were given a choice between a previously visited feeder and an unvisited one, both containing a rich, unscented sucrose solution. There was no difference in the number of visits to the two treatments. However, some individuals chose the feeder on one side more often. We conclude that foragers of this species of wasp do not use odor marks left behind by nestmates to find food, but they do exhibit the tendency, when returning to a food source that has not been depleted, to choose a resource based on its relative position, presumably by using visual cues.

  6. Individual-specific transgenerational marking of fish populations based on a barium dual-isotope procedure.

    Science.gov (United States)

    Huelga-Suarez, Gonzalo; Moldovan, Mariella; Garcia-Valiente, America; Garcia-Vazquez, Eva; Alonso, J Ignacio Garcia

    2012-01-03

    The present study focuses on the development and evaluation of an individual-specific transgenerational marking procedure using two enriched barium isotopes, (135)Ba and (137)Ba, mixed at a given and selectable molar ratio. The method is based on the deconvolution of the isotope patterns found in the sample into four molar contribution factors: natural xenon (Xe nat), natural barium (Ba nat), Ba135, and Ba137. The ratio of molar contributions between Ba137 and Ba135 is constant and independent of the contribution of natural barium in the sample. This procedure was tested in brown trout ( Salmo trutta ) kept in captivity. Trout were injected with three different Ba137/Ba135 isotopic signatures ca. 7 months and 7 days before spawning to compare the efficiency of the marking procedure at long and short term, respectively. The barium isotopic profiles were measured in the offspring by means of inductively coupled plasma mass spectrometry. Each of the three different isotopic signatures was unequivocally identified in the offspring in both whole eggs and larvae. For 9 month old offspring, the characteristic barium isotope signatures could also be detected in the otoliths even in the presence of a high and variable amount of barium of natural isotope abundance. In conclusion, it can be stated that the proposed dual-isotope marking is inheritable and can be detected after both long-term and short-term marking. Furthermore, the dual-isotope marking can be made individual-specific, so that it allows identification of offspring from a single individual or a group of individuals within a given fish group. © 2011 American Chemical Society

  7. Skin markings in external radiotherapy by temporary tattooing with henna: Improvement of accuracy and increased patient comfort

    International Nuclear Information System (INIS)

    Wurstbauer, Karl; Sedlmayer, Felix; Kogelnik, H. Dieter

    2001-01-01

    Purpose: To guarantee invariable skin markings in patients undergoing a course of external radiotherapy, especially using conformal techniques. Cutaneous markings with henna also increase patient comfort, because washing and showering are allowed. Methods and Materials: Henna, a completely natural product, is a skin colorant with a history of 5,000 years. It is applied to the skin in the form of a paste. While drying, henna stains the superficial skin layers for several weeks, and the marked area can be exposed to water arbitrarily. In case of fading of the stain before the end of radiotherapy, the marking procedure can be repeated. From November 1998 until March 2000, we performed skin markings with henna in 158 patients with different tumor sites. The majority of patients received conformal radiotherapy techniques. All patients have been evaluated concerning durability of the markings, the required number of marking procedures per treatment course, and possible related side effects. Results: The median durability of henna staining is 23 days (range 12-48 days). On average, two marking procedures (range 1-4) are necessary for a patient treated with curative intent. Although washing and showering are freely permitted, no adverse cutaneous side effects (e.g., erythema, allergic reactions) have been observed. Conclusions: Skin marking by temporary tattooing with henna increases the accuracy of external radiotherapy. It yields stable and invariable markings for the entire course of radiotherapy and also increases the comfort of patients

  8. Preoperative Site Marking: Are We Adhering to Good Surgical Practice?

    Science.gov (United States)

    Bathla, Sonia; Chadwick, Michael; Nevins, Edward J; Seward, Joanna

    2017-06-29

    Wrong-site surgery is a never event and a serious, preventable patient safety incident. Within the United Kingdom, national guidance has been issued to minimize the risk of such events. The mandate includes preoperative marking of all surgical patients. This study aimed to quantify regional variation in practice within general surgery and opinions of the surgeons, to help guide the formulation and implementation of a regional general surgery preoperative marking protocol. A SurveyMonkey questionnaire was designed and distributed to 120 surgeons within the Mersey region, United Kingdom. This included all surgical trainees in Mersey (47 registrars, 56 core trainees), 15 consultants, and 2 surgical care practitioners. This sought to ascertain their routine practice and how they would choose to mark for 12 index procedures in general surgery, if mandated to do so. A total of 72 responses (60%) were obtained to the SurveyMonkey questionnaire. Only 26 (36.1%) said that they routinely marked all of their patients preoperatively. The operating surgeon marked the patient in 69% of responses, with the remainder delegating this task. Markings were visible after draping in only 55.6% of marked cases. Based on our findings, surgeons may not be adhering to "Good Surgical Practice"; practice is widely variable and surgeons are largely opposed and resistant to marking patients unless laterality is involved. We suggest that all surgeons need to be actively engaged in the design of local marking protocols to gain support, change practice, and reduce errors.

  9. Virtual tool mark generation for efficient striation analysis in forensic science

    Energy Technology Data Exchange (ETDEWEB)

    Ekstrand, Laura [Iowa State Univ., Ames, IA (United States)

    2012-01-01

    In 2009, a National Academy of Sciences report called for investigation into the scienti c basis behind tool mark comparisons (National Academy of Sciences, 2009). Answering this call, Chumbley et al. (2010) attempted to prove or disprove the hypothesis that tool marks are unique to a single tool. They developed a statistical algorithm that could, in most cases, discern matching and non-matching tool marks made at di erent angles by sequentially numbered screwdriver tips. Moreover, in the cases where the algorithm misinterpreted a pair of marks, an experienced forensics examiner could discern the correct outcome. While this research served to con rm the basic assumptions behind tool mark analysis, it also suggested that statistical analysis software could help to reduce the examiner's workload. This led to a new tool mark analysis approach, introduced in this thesis, that relies on 3D scans of screwdriver tip and marked plate surfaces at the micrometer scale from an optical microscope. These scans are carefully cleaned to remove noise from the data acquisition process and assigned a coordinate system that mathematically de nes angles and twists in a natural way. The marking process is then simulated by using a 3D graphics software package to impart rotations to the tip and take the projection of the tip's geometry in the direction of tool travel. The edge of this projection, retrieved from the 3D graphics software, becomes a virtual tool mark. Using this method, virtual marks are made at increments of 5 and compared to a scan of the evidence mark. The previously developed statistical package from Chumbley et al. (2010) performs the comparison, comparing the similarity of the geometry of both marks to the similarity that would occur due to random chance. The resulting statistical measure of the likelihood of the match informs the examiner of the angle of the best matching virtual mark, allowing the examiner to focus his/her mark analysis on a smaller range of angles

  10. Residual Strength Characterization of Unitized Structures Fabricated Using Different Manufacturing Technologies

    Science.gov (United States)

    Seshadri, B. R.; Smith, S. W.; Johnston, W. M.

    2008-01-01

    This viewgraph presentation describes residual strength analysis of integral structures fabricated using different manufacturing procedures. The topics include: 1) Built-up and Integral Structures; 2) Development of Prediction Methodology for Integral Structures Fabricated using different Manufacturing Procedures; 3) Testing Facility; 4) Fracture Parameters Definition; 5) Crack Branching in Integral Structures; 6) Results and Discussion; and 7) Concluding Remarks.

  11. Selection of gender marked morphemes in speech production

    NARCIS (Netherlands)

    Schriefers, H.J.; Jescheniak, J.D.; Hantsch, A.

    2005-01-01

    N.O. Schiller and A. Caramazza (2003) and A. Costa, D. Kovacic, E. Fedorenko, and A. Caramazza (2003) have argued that the processing of freestanding gender-marked morphemes (e.g., determiners) and bound gender-marked morphemes (e.g., adjective suffixes) during syntactic encoding in speech

  12. The Structure of Vocational Interests in Germany: Different Methodologies, Different Conclusions

    Science.gov (United States)

    Nagy, Gabriel; Trautwein, Ulrich; Ludtke, Oliver

    2010-01-01

    The cross-cultural generalizability of vocational interest structures has received significant attention in recent years. This article adds to this research in four respects. First, data from a context that has not previously been investigated (Germany) was analyzed. Second, students at different stages of their educational career were examined.…

  13. A method for studying knife tool marks on bone.

    Science.gov (United States)

    Shaw, Kai-Ping; Chung, Ju-Hui; Chung, Fang-Chun; Tseng, Bo-Yuan; Pan, Chih-Hsin; Yang, Kai-Ting; Yang, Chun-Pang

    2011-07-01

    The characteristics of knife tool marks retained on hard tissues can be used to outline the shape and angle of a knife. The purpose of this study was to describe such marks on bone tissues that had been chopped with knives. A chopping stage with a gravity accelerator and a fixed bone platform was designed to reconstruct the chopping action. A digital microscope was also used to measure the knife angle (θ) and retained V-shape tool mark angle (ψ) in a pig skull. The κ value (elasticity coefficient; θ/ψ) was derived and recorded after the knife angle (θ) and the accompanied velocity were compared with the proportional impulsive force of the knife and ψ on the bone. The constant impulsive force revealed a correlation between the V-shape tool mark angle (ψ) and the elasticity coefficient (κ). These results describe the tool marks--crucial in the medicolegal investigation--of a knife on hard tissues. © 2011 American Academy of Forensic Sciences.

  14. Uncertainties Affecting BOSFN for the Mark 15 Assembly

    International Nuclear Information System (INIS)

    Hamm, L.L.

    2001-01-01

    Technical and transient protection limits are specified on the nominal burnout safety factor, BOSFN, to avoid significant release of fission products caused by local film boiling burnout. The risk of fission product release, BOR, due to film boiling burnout is statistically determined where allowances are made to account for differences between the nominal assembly and the actual assembly. This report describes the calculational model behind BOR and how the specific numerical values were estimated. The data listed in this report enable damage calculations with COBAD to be performed for the Mark 15 assembly

  15. Using road markings as a continuous cue for speed choice.

    Science.gov (United States)

    Charlton, Samuel G; Starkey, Nicola J; Malhotra, Neha

    2018-08-01

    The potential for using road markings to indicate speed limits was investigated in a driving simulator over the course of two sessions. Two types of experimental road markings, an "Attentional" set designed to provide visually distinct cues to indicate speed limits of 60, 80 and 100 km/h, and a "Perceptual" set designed to also affect drivers' perception of speed, were compared to a standard undifferentiated set of markings. Participants (n = 20 per group) were assigned to one of four experimental groups (Attentional-Explicit, Attentional-Implicit, Perceptual-Explicit, Perceptual-Implicit) or a Control group (n = 22; standard road markings). The Explicit groups were instructed about the meaning of the road markings while those in the Implicit and Control groups did not receive any explanation. Participants drove five 10 km simulated roads containing three speed zones (60, 80 and 100 km/h) during the first session. The participants returned to the laboratory approximately 3 days later to drive five more trials including roads they had not seen before, a trial that included a secondary task, and a trial where speed signs were removed and only markings were present. The findings indicated that both types of road markings improved drivers' compliance with speed limits compared to the control group, but that explicit instruction as to the meaning of the markings was needed to realise their full benefit. Although previous research has indicated the benefit of road markings used as warnings to indicate speed reductions in advance of horizontal or vertical curves, the findings of the present experiment also suggest that systematically associating road markings with specific speed limits may be a useful way to improve speed limit compliance and increase speed homogeneity. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Settlement determination of operating moisture of autoclaved aerated concrete in different climatic zones

    Directory of Open Access Journals (Sweden)

    Pastushkov Pavel Pavlovich

    Full Text Available In the process of operation of buildings the moisture state of enveloping structures materials is changing depending on their construction features, properties of the material, temperature and moisture conditions in the premises, climatic conditions of the construction area. Moisture mode determines the operational properties of the enveloping structures of a building. It directly influences the thermal characteristics of enveloping structure and energy efficiency of the applied materials. The analysis of the methods for calculation of moisture behavior of enclosing structures is carried out. The research relevance of operational moisture of AAC is substantiated. Experimental studies and results of the sorption moisturizing and water vapor permeability of leading marks of aerated concrete are carried out. The authors offer the results of numerical calculations of the moisture behavior of aerated concrete in the walls with mark D400 with facade thermal insulation composite systems - with external plaster layers for different climatic zones of construction.

  17. Variable features on Mars. VII - Dark filamentary markings on Mars

    Science.gov (United States)

    Veverka, J.

    1976-01-01

    The paper discusses the location, variability, and possible nature of well-developed patterns of dark filamentary markings in the Mariner 9 photographic records. Although not common on Mars, the markings are concentrated in at least two areas: Depressio Hellespontica and Cerberus/Trivium Charontis. In certain localities, strong winds are required to bring these markings into prominence. The dark filamentary markings seem to be true albedo features controlled by local topography, it being unlikely that they are free linear dunes. The distinctive criss-cross pattern seen in many of the pictures suggests that jointing provides the controlling topographic grid. At this stage it cannot be inferred whether the markings are erosional or depositional in character.

  18. The Mark II Vertex Drift Chamber

    International Nuclear Information System (INIS)

    Alexander, J.P.; Baggs, R.; Fujino, D.

    1989-03-01

    We have completed constructing and begun operating the Mark II Drift Chamber Vertex Detector. The chamber, based on a modified jet cell design, achieves 30 μm spatial resolution and 2 gas mixtures. Special emphasis has been placed on controlling systematic errors including the use of novel construction techniques which permit accurate wire placement. Chamber performance has been studied with cosmic ray tracks collected with the chamber located both inside and outside the Mark II. Results on spatial resolution, average pulse shape, and some properties of CO 2 mixtures are presented. 10 refs., 12 figs., 1 tab

  19. Acceptance and stress effects of aircraft obstruction markings of wind turbines

    International Nuclear Information System (INIS)

    Pohl, Johannes; Hübner, Gundula; Mohs, Anja

    2012-01-01

    A dominant resistance factor against wind power projects seems to be their visual impact on the landscape. In addition stress effects from aircraft obstruction markings are an emerging topic related to acceptance. As the height of wind turbines increases, so does the number of mandatory obstruction markings. Recently, obstruction markings have caused a growing number of complaints from residents. Whether obstruction markings indeed cause stress or even substantial annoyance remains an open question. To analyse the stress impact of obstruction markings, we used environmental and stress psychology methodologies. Residents (N=420) with direct sight of turbines at 13 wind farms participated in a questionnaire survey. Evidence of substantial annoyance caused by obstruction markings was not found. However, residents exposed to xenon lights reported more intense and multifaceted stress responses than exposed to LED or colour markings on blades. Moreover, xenon lights negatively affected the general acceptance of wind energy. Additionally, synchronised navigation lights were found to be less annoying than non-synchronised lights under certain weather conditions. Markings with light intensity adjustment proved to be advantageous. To reduce stress and increase social acceptance of wind power, xenon lights should be abandoned, navigation lights synchronised, and light intensity adjustment applied. - Research highlights: ► Wind turbine obstruction markings influence the social acceptance of wind energy. ► Residents exposed to xenon lights reported more intense stress responses than exposed to LED or colour markings. ► Synchronised lights were found to be less annoying under certain weather conditions. ► Markings with light intensity adjustment proved to be advantageous. ► Evidence of substantial annoyance caused by obstruction markings was not found.

  20. Administering and Detecting Protein Marks on Arthropods for Dispersal Research.

    Science.gov (United States)

    Hagler, James R; Machtley, Scott A

    2016-01-28

    Monitoring arthropod movement is often required to better understand associated population dynamics, dispersal patterns, host plant preferences, and other ecological interactions. Arthropods are usually tracked in nature by tagging them with a unique mark and then re-collecting them over time and space to determine their dispersal capabilities. In addition to actual physical tags, such as colored dust or paint, various types of proteins have proven very effective for marking arthropods for ecological research. Proteins can be administered internally and/or externally. The proteins can then be detected on recaptured arthropods with a protein-specific enzyme-linked immunosorbent assay (ELISA). Here we describe protocols for externally and internally tagging arthropods with protein. Two simple experimental examples are demonstrated: (1) an internal protein mark introduced to an insect by providing a protein-enriched diet and (2) an external protein mark topically applied to an insect using a medical nebulizer. We then relate a step-by-step guide of the sandwich and indirect ELISA methods used to detect protein marks on the insects. In this demonstration, various aspects of the acquisition and detection of protein markers on arthropods for mark-release-recapture, mark-capture, and self-mark-capture types of research are discussed, along with the various ways that the immunomarking procedure has been adapted to suit a wide variety of research objectives.

  1. Preoperative stoma site marking in the general surgery population.

    Science.gov (United States)

    Zimnicki, Katherine M

    2013-01-01

    Preoperative teaching and stoma site marking are supported by research and professional organizations as interventions that can reduce the incidence of problematic stomas and improve patient outcomes. This study investigated the translation of this research into practice in the acute care surgery population. A retrospective chart review using convenience sampling was conducted at a large urban hospital in the Midwestern United States. Thirty patients underwent a surgical procedure that resulted in the creation of a fecal ostomy over a 5-month period. Descriptive statistical analysis examined the reason for surgery, preoperative length of stay (LOS), the percentage of patients who received preoperative teaching and stoma marking and the relationship between preoperative LOS and the use of preoperative teaching and stoma marking. Twenty-one of 30 patients were admitted to hospital 24 hours or more before surgery. No participants were admitted urgently. Three (14%) of those admitted for more than 24 hours received preoperative marking or teaching. There was no significant relationship between preoperative LOS and preoperative teaching and stoma marking. The opportunity exists to promote successful adaptation in this surgical population through the implementation of the evidence-based interventions of preoperative teaching and stoma marking. Additional study is needed to determine barriers to their use as well as to develop effective implementation strategies.

  2. Banner Marks of Ottoman Perıod at Giresun Museum

    Directory of Open Access Journals (Sweden)

    Gazanfer İLTAR

    2015-12-01

    Full Text Available The eleven banner marks among those that were brought together in 1926 to establish a museum at Tokat Gök Medrese (the Celestial Madrasa was sent to Giresun Museum in 1995 in order to be displayed together with other two thousand archaeological and ethnographic pieces. On the banner of one of these marks that was produced with brass hammering technique was written the date “1118/1706-1707”, which is indicated on its inventory record. Such marks that were decorated by using thuluth writing and vegetative motifs were made in the forms of round, drop, palmet and tulip. Generally, there exists a hilly part in the forms of palmet and drop on most of these marks which consist a handle and a body part. Additionally, there appear writings as “Allah, Muhammed, the words of Tawheed, Allah-Muhammed-Ali” on these marks. Today, the marks some of which are exhibited on the display cases and some of which are stored in museums are important in the sense of obtaining information about the art of metalworking in the period these marks were produced.

  3. Synthesis of gold nanoparticles with different atomistic structural characteristics

    International Nuclear Information System (INIS)

    Esparza, R.; Rosas, G.; Lopez Fuentes, M.; Sanchez Ramirez, J.F.; Pal, U.; Ascencio, J.A.; Perez, R.

    2007-01-01

    A chemical reduction method was used to produce nanometric gold particles. Depending on the concentration of the main reactant compound different nanometric sizes and consequently different atomic structural configurations of the particles are obtained. Insights on the structural nature of the gold nanoparticles are obtained through a comparison between digitally-processed experimental high-resolution electron microscopy images and theoretically-simulated images obtained with a multislice approach of the dynamical theory of electron diffraction. Quantum molecular mechanical calculations, based on density functional theory, are carried out to explain the relationships between the stability of the gold nanoparticles, the atomic structural configurations and the size of nanoparticles

  4. Effect of different temperature-time combinations on physicochemical, microbiological, textural and structural features of sous-vide cooked lamb loins.

    Science.gov (United States)

    Roldán, Mar; Antequera, Teresa; Martín, Alberto; Mayoral, Ana Isabel; Ruiz, Jorge

    2013-03-01

    Lamb loins were subjected to sous-vide cooking at different combinations of temperature (60, 70, and 80 °C) and time (6, 12, and 24 h). Different physicochemical, histological and structural parameters were studied. Increasing cooking temperatures led to higher weight losses and lower moisture contents, whereas the effect of cooking time on these variables was limited. Samples cooked at 60 °C showed the highest lightness and redness, while increasing cooking temperature and cooking time produced higher yellowness values. Most textural variables in a texture profile analysis showed a marked interaction between cooking temperature and time. Samples cooked for 24h showed significantly lower values for most of the studied textural parameters for all the temperatures considered. Connective tissue granulation at 60 °C and gelation at 70 °C were observed in the SEM micrographs. The sous-vide cooking of lamb loins dramatically reduced microbial population even with the less intense heat treatment studied (60 °C-6 h). Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Factors affecting scent-marking behaviour in Eurasion beaver (Castor fiber)

    NARCIS (Netherlands)

    Rosell, F.; Nolet, B.A.

    1997-01-01

    We tested the hypothesis that a main function of territory marking in Eurasian beaver (Castor fiber) is defense of the territory. The results showed that: (1) beaver colonies with close neighbors scent-mark more often than isolated ones; (2) the number of scent markings increased significantly with

  6. 46 CFR 169.755 - Draft marks and draft indicating systems.

    Science.gov (United States)

    2010-10-01

    ... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

  7. 9 CFR 592.320 - Products that may bear the inspection mark.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Products that may bear the inspection... Marking Products § 592.320 Products that may bear the inspection mark. Products that are permitted to bear... products eligible to bear the inspection mark and may contain other edible ingredients. The official mark...

  8. 27 CFR 20.33 - Time of destruction of marks and brands.

    Science.gov (United States)

    2010-04-01

    ... marks and brands. 20.33 Section 20.33 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... Administrative Provisions Marks and Brands § 20.33 Time of destruction of marks and brands. (a) Any person who... alcohol or specially denatured rum shall immediately destroy or obliterate the marks, brands, and labels...

  9. Ülar Mark: loome uut ja iga loomisega lammutame midagi / Ülar Mark ; intervjueerinud Mikk Salu

    Index Scriptorium Estoniae

    Mark, Ülar, 1968-

    2010-01-01

    Eesti Arhitektuurikeskuse juhatuse esimees, arhitekt Ülar Mark Tallinna arhitektuurist ja linna arengust, demokraatlikust linnaruumist. Pikemalt Solarise keskusest, vabadussambast, väikepoodide asemele suurte kaubanduskeskuste tulekust

  10. Laser direct marking applied to rasterizing miniature Data Matrix Code on aluminum alloy

    Science.gov (United States)

    Li, Xia-Shuang; He, Wei-Ping; Lei, Lei; Wang, Jian; Guo, Gai-Fang; Zhang, Teng-Yun; Yue, Ting

    2016-03-01

    Precise miniaturization of 2D Data Matrix (DM) Codes on Aluminum alloy formed by raster mode laser direct part marking is demonstrated. The characteristic edge over-burn effects, which render vector mode laser direct part marking inadequate for producing precise and readable miniature codes, are minimized with raster mode laser marking. To obtain the control mechanism for the contrast and print growth of miniature DM code by raster laser marking process, the temperature field model of long pulse laser interaction with material is established. From the experimental results, laser average power and Q frequency have an important effect on the contrast and print growth of miniature DM code, and the threshold of laser average power and Q frequency for an identifiable miniature DM code are respectively 3.6 W and 110 kHz, which matches the model well within normal operating conditions. In addition, the empirical model of correlation occurring between laser marking parameters and module size is also obtained, and the optimal processing parameter values for an identifiable miniature DM code of different but certain data size are given. It is also found that an increase of the repeat scanning number effectively improves the surface finish of bore, the appearance consistency of modules, which has benefit to reading. The reading quality of miniature DM code is greatly improved using ultrasonic cleaning in water by avoiding the interference of color speckles surrounding modules.

  11. 7 CFR 319.37-10 - Marking and identity.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 319.37-10 Section 319.37-10 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION..., and Other Plant Products 1,2 § 319.37-10 Marking and identity. (a) Any restricted article for...

  12. 46 CFR 167.55-1 - Draft marks and draft indicating systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 167.55-1... NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... aft to the location of the draft marks, due to a raked stem or cut away skeg, the draft must be...

  13. Tense Marking in the English Narrative Retells of Dual Language Preschoolers.

    Science.gov (United States)

    Gusewski, Svenja; Rojas, Raúl

    2017-07-26

    This longitudinal study investigated the emergence of English tense marking in young (Spanish-English) dual language learners (DLLs) over 4 consecutive academic semesters, addressing the need for longitudinal data on typical acquisition trajectories of English in DLL preschoolers. Language sample analysis was conducted on 139 English narrative retells elicited from 39 preschool-age (Spanish-English) DLLs (range = 39-65 months). Growth curve models captured within- and between-individual change in tense-marking accuracy over time. Tense-marking accuracy was indexed by the finite verb morphology composite and by 2 specifically developed adaptations. Individual tense markers were systematically described in terms of overall accuracy and specific error patterns. Tense-marking accuracy exhibited significant growth over time for each composite. Initially, irregular past-tense accuracy was higher than regular past-tense accuracy; over time, however, regular past-tense marking outpaced accuracy on irregular verbs. These findings suggest that young DLLs can achieve high tense-marking accuracy assuming 2 years of immersive exposure to English. Monitoring the growth in tense-marking accuracy over time and considering productive tense-marking errors as partially correct more precisely captured the emergence of English tense marking in this population with highly variable expressive language skills. https://doi.org/10.23641/asha.5176942.

  14. A simple method to compare firing pin marks using stereomicroscope and Microsoft office (Windows 8) tools.

    Science.gov (United States)

    Suresh, R

    2017-08-01

    Pertinent marks of fired cartridge cases such as firing pin, breech face, extractor, ejector, etc. are used for firearm identification. A non-standard semiautomatic pistol and four .22rim fire cartridges (head stamp KF) is used for known source comparison study. Two test fired cartridge cases are examined under stereomicroscope. The characteristic marks are captured by digital camera and comparative analysis of striation marks is done by using different tools available in the Microsoft word (Windows 8) of a computer system. The similarities of striation marks thus obtained are highly convincing to identify the firearm. In this paper, an effort has been made to study and compare the striation marks of two fired cartridge cases using stereomicroscope, digital camera and computer system. Comparison microscope is not used in this study. The method described in this study is simple, cost effective, transport to field study and can be equipped in a crime scene vehicle to facilitate immediate on spot examination. The findings may be highly helpful to the forensic community, law enforcement agencies and students. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Multi-Disciplinary Peer-Mark Moderation of Group Work

    Science.gov (United States)

    Willmot, Peter; Pond, Keith

    2012-01-01

    Self and peer assessment offers benefits for enhancing student learning. Peer moderation provides a convenient solution for awarding individual marks in group assignments. This paper provides a significant review of peer-mark moderation, and describes an award winning, web-based tool that was developed in the UK and is now spreading across the…

  16. 49 CFR 174.59 - Marking and placarding of rail cars.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Marking and placarding of rail cars. 174.59... RAIL General Handling and Loading Requirements § 174.59 Marking and placarding of rail cars. No person may transport a rail car carrying hazardous materials unless it is marked and placarded as required by...

  17. Soil-Borne Microbial Functional Structure across Different Land Uses

    NARCIS (Netherlands)

    Kuramae, E.E.; Zhou, J.Z.; Kowalchuk, G.A.; van Veen, J.A..

    2014-01-01

    Land use change alters the structure and composition of microbial communities. However, the links between environmental factors and microbial functions are not well understood. Here we interrogated the functional structure of soil microbial communities across different land uses. In a multivariate

  18. Soil-borne microbial functional structure across different land uses

    NARCIS (Netherlands)

    Kuramae, Eiko E; Zhou, Jizhong Z; Kowalchuk, George A; van Veen, Johannes A

    2014-01-01

    Land use change alters the structure and composition of microbial communities. However, the links between environmental factors and microbial functions are not well understood. Here we interrogated the functional structure of soil microbial communities across different land uses. In a multivariate

  19. Evaluation of Isotope 32P Method to Mark Culex pipiens (Diptera: Culicidae in a Laboratory

    Directory of Open Access Journals (Sweden)

    Chongxing Zhang

    2016-01-01

    Full Text Available Background: The aim of the current study was to develop a marking technique as an internal marker to mark post blood meal mosquitoes by using stable phosphate isotope 32P and determine the optimal concentration of it.Methods: An isotonic physiological saline solution, containing different concentration of radioactive isotope 32P-labeled disodium phosphate (Na2H32PO4 was injected into rabbits via the jugular vein in the laboratory. Emerged Cx. pipiens were marked after feeding on rabbit. At the same time, the labeled conditions of emerged Cx. pipiens were also measured by placing feces of No. 6 rabbit into containers with mosquito larvae and pupae inside.Results: According to the label condition of Cx. pipiens after taking blood and the effect of different dosage Na2H32PO4 on rabbit health, the optimal concentration of radioactive isotope was determined, that is, 0.1211 mCi/kg. By placing feces of No. 6 rabbit into containers with mosquito larvae and pupae inside, the emerged mosquitoes were also labeled. Therefore, feeding mosquitoes on the animal injected with radioactive Na2H32PO4 was more prac­tical for detecting and tracing mosquitoes.Conclusion: The method was less time-consuming, more sensitive and safer. This marking method will facilitate post-bloodmeal studies of mosquitoes and other blood-sucking insects.

  20. Scent marking behavior as an odorant communication in mice

    Science.gov (United States)

    Arakawa, Hiroyuki; Blanchard, D. Caroline; Arakawa, Keiko; Dunlap, Christopher; Blanchard, Robert J.

    2008-01-01

    In rodents, where chemical signals play a particularly important role in determining intraspecies interactions including social dominance and intersexual relationships, various studies have shown that behavior is sensitive to conspecific odor cues. Mice use urinary scent marks for communication with individual conspecifics in many social contexts. Urinary scent involves genetic information about individuals such as species, sex, and individual identity as well as metabolic information such as social dominance, and reproductive and health status, which are mediated by chemical proteins in scent marks including the major histocompatibility complex and the major urinary proteins. The odor of the predator which can be considered to be a threatening signal for the prey also modulate mouse behavior in which scent marking is suppressed in response to the cat odor exposure in mice. These odorant chemicals are detected and recognized through two olfactory bulbs, the role of which in detection of chemosignals with biological relevant appears to be differential, but partly overlapped. Mice deposit scent marks toward conspecifics to maintain their social relationships, and inhibit scent marking in a context where natural predator, cat odor is contained. This suppression of scent marking is long-lasting (for at least 7 days) and context-dependent, while the odorant signaling to conspecifics tends to appear frequently (over 24 hrs but less than 7 days intervals) depending on the familiarity of each signal-recipient. It has been discussed that scent marking is a communicative behavior associated with territoriality toward conspecifics, indicating that the social signaling within species are sensitive to predator odor cues in terms of vulnerability to predation risk. PMID:18565582

  1. Decommissioning plan for the TRIGA mark-3

    International Nuclear Information System (INIS)

    Park, S. K.; Jung, W. S.; Jung, K. H.; Baek, S. T.; Jung, K. J.

    1999-01-01

    TRIGA Mark-III (KRR-2) is the second research reactor in Korea. Construction of KRR-2 was started in 1969 and first criticality was achieved in 1972. After 24 years operation, KRR-2 has stopped its operation at the end of 1995 due to normal operation of HANARO. KRR-2 was then decided to decommission in 1996 by government. Decontamination and decommissioning (D and D) will be conducted in accordance with domestic laws and international regulations. Selected method of D and D will be devoted to protect workers and environment and to minimize radioactive wastes produced. The major D and D work will be conducted safely by using conventional industrial equipment because of relatively low radioactivity and contamination in the facility. When removing activated concrete from reactor pool, it will be installed a temporary containment and ventilation system. In this paper, structure of KRR-2 and method of D and D in each step are presented and discussed

  2. 27 CFR 26.106 - Marking containers of beer.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marking containers of beer... Liquors and Articles in Puerto Rico Beer § 26.106 Marking containers of beer. Containers of beer of Puerto... brewer; the serial number, capacity, and size of the container; the kind of beer; and the serial number...

  3. 27 CFR 26.97 - Marking containers of wine.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marking containers of wine... Liquors and Articles in Puerto Rico Wine § 26.97 Marking containers of wine. Containers of wine of Puerto... winemaker, the serial number of the container, the kind and taxable grade of the wine, the gallon content...

  4. BRAKER1: Unsupervised RNA-Seq-Based Genome Annotation with GeneMark-ET and AUGUSTUS.

    Science.gov (United States)

    Hoff, Katharina J; Lange, Simone; Lomsadze, Alexandre; Borodovsky, Mark; Stanke, Mario

    2016-03-01

    Gene finding in eukaryotic genomes is notoriously difficult to automate. The task is to design a work flow with a minimal set of tools that would reach state-of-the-art performance across a wide range of species. GeneMark-ET is a gene prediction tool that incorporates RNA-Seq data into unsupervised training and subsequently generates ab initio gene predictions. AUGUSTUS is a gene finder that usually requires supervised training and uses information from RNA-Seq reads in the prediction step. Complementary strengths of GeneMark-ET and AUGUSTUS provided motivation for designing a new combined tool for automatic gene prediction. We present BRAKER1, a pipeline for unsupervised RNA-Seq-based genome annotation that combines the advantages of GeneMark-ET and AUGUSTUS. As input, BRAKER1 requires a genome assembly file and a file in bam-format with spliced alignments of RNA-Seq reads to the genome. First, GeneMark-ET performs iterative training and generates initial gene structures. Second, AUGUSTUS uses predicted genes for training and then integrates RNA-Seq read information into final gene predictions. In our experiments, we observed that BRAKER1 was more accurate than MAKER2 when it is using RNA-Seq as sole source for training and prediction. BRAKER1 does not require pre-trained parameters or a separate expert-prepared training step. BRAKER1 is available for download at http://bioinf.uni-greifswald.de/bioinf/braker/ and http://exon.gatech.edu/GeneMark/ katharina.hoff@uni-greifswald.de or borodovsky@gatech.edu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  5. Mirror-mark tests performed on jackdaws reveal potential methodological problems in the use of stickers in avian mark-test studies.

    Directory of Open Access Journals (Sweden)

    Manuel Soler

    Full Text Available Some animals are capable of recognizing themselves in a mirror, which is considered to be demonstrated by passing the mark test. Mirror self-recognition capacity has been found in just a few mammals having very large brains and only in one bird, the magpie (Pica pica. The results obtained in magpies have enormous biological and cognitive implications because the fact that magpies were able to pass the mark test meant that this species is at the same cognitive level with great apes, that mirror self-recognition has evolved independently in the magpie and great apes (which diverged 300 million years ago, and that the neocortex (which is not present in the bird's brains is not a prerequisite for mirror self-recognition as previously believed. Here, we have replicated the experimental design used on magpies to determine whether jackdaws (Corvus monedula are also capable of mirror self-recognition by passing the mark test. We found that our nine jackdaws showed a very high interest towards the mirror and exhibited self-contingent behavior as soon as mirrors were introduced. However, jackdaws were not able to pass the mark test: both sticker-directed actions and sticker removal were performed with a similar frequency in both the cardboard (control and the mirror conditions. We conclude that our jackdaws' behaviour raises non-trivial questions about the methodology used in the avian mark test. Our study suggests that the use of self-adhesive stickers on sensitive throat feathers may open the way to artefactual results because birds might perceive the stickers tactilely.

  6. A comparison of the structure of ovules and seeds in Stemona (Stemonaceae) and Pentastemona (Pentastemonaceae)

    NARCIS (Netherlands)

    Bouman, F.; Devente, N.

    1992-01-01

    Stemona and Pentastemona differ clearly in the size and structure of their ovules and seeds. Especially the development, shape, and cell wall thickenings of the endotestal cells, and by consequence the origin of the seed ridges, show marked differences. The embryological and seed anatomical

  7. Aksel Mark: kõik algaski Otsal / Enn Nõu

    Index Scriptorium Estoniae

    Nõu, Enn, 1933-

    2012-01-01

    Arvustus: Mark Beijer, Mai. Landkänning : Brevväxling mellan Anu och Aksel Mark under deras första år som flyktingar från Estland 1944-45. Stockholm : Bokverksta´n Förlag, 2008; Allt började på Otsa : minnen från min barndom och skoláren. Stockholm : Beijer Bok & Skog, 2011

  8. Different Structures of PVA Nanofibrous Membrane for Sound Absorption Application

    Directory of Open Access Journals (Sweden)

    Jana Mohrova

    2012-01-01

    Full Text Available The thin nanofibrous layer has different properties in the field of sound absorption in comparison with porous fibrous material which works on a principle of friction of air particles in contact with walls of pores. In case of the thin nanofibrous layer, which represents a sound absorber here, the energy of sonic waves is absorbed by the principle of membrane resonance. The structure of the membrane can play an important role in the process of converting the sonic energy to a different energy type. The vibration system acts differently depending on the presence of smooth fibers in the structure, amount of partly merged fibers, or structure of polymer foil as extreme. Polyvinyl alcohol (PVA was used as a polymer because of its good water solubility. It is possible to influence the structure of nanofibrous layer during the production process thanks to this property of polyvinyl alcohol.

  9. Mark Leonard : EL ei peakski olema suurvõim / Mark Leonard ; interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Leonard, Mark

    2008-01-01

    Intervjuu Euroopa Välissuhete Nõukogu tegevdirektoriga, kes vastab küsimustele, mis puudutavad USA ja Euroopa suhteid, Euroopa Liidu välispoliitikat, Venemaa ja Euroopa Liidu suhteid pärast Gruusia konflikti. Ta peab murettekitavaks, et Venemaa üritab takistada euroopalike väärtuste levitamist oma naaberriikides. Vt. samas: Mark Leonard. Ilmunud ka Sirp : Diplomaatia 14. nov. nr. 11 lk. 13-14

  10. StirMark Benchmark: audio watermarking attacks based on lossy compression

    Science.gov (United States)

    Steinebach, Martin; Lang, Andreas; Dittmann, Jana

    2002-04-01

    StirMark Benchmark is a well-known evaluation tool for watermarking robustness. Additional attacks are added to it continuously. To enable application based evaluation, in our paper we address attacks against audio watermarks based on lossy audio compression algorithms to be included in the test environment. We discuss the effect of different lossy compression algorithms like MPEG-2 audio Layer 3, Ogg or VQF on a selection of audio test data. Our focus is on changes regarding the basic characteristics of the audio data like spectrum or average power and on removal of embedded watermarks. Furthermore we compare results of different watermarking algorithms and show that lossy compression is still a challenge for most of them. There are two strategies for adding evaluation of robustness against lossy compression to StirMark Benchmark: (a) use of existing free compression algorithms (b) implementation of a generic lossy compression simulation. We discuss how such a model can be implemented based on the results of our tests. This method is less complex, as no real psycho acoustic model has to be applied. Our model can be used for audio watermarking evaluation of numerous application fields. As an example, we describe its importance for e-commerce applications with watermarking security.

  11. Reproducibility of Computer-Aided Detection Marks in Digital Mammography

    International Nuclear Information System (INIS)

    Kim, Seung Ja; Moon, Woo Kyung; Cho, Nariya; Kim, Sun Mi; Im, Jung Gi; Cha, Joo Hee

    2007-01-01

    To evaluate the performance and reproducibility of a computeraided detection (CAD) system in mediolateral oblique (MLO) digital mammograms taken serially, without release of breast compression. A CAD system was applied preoperatively to the fulfilled digital mammograms of two MLO views taken without release of breast compression in 82 patients (age range: 33 83 years; mean age: 49 years) with previously diagnosed breast cancers. The total number of visible lesion components in 82 patients was 101: 66 masses and 35 microcalcifications. We analyzed the sensitivity and reproducibility of the CAD marks. The sensitivity of the CAD system for first MLO views was 71% (47/66) for masses and 80% (28/35) for microcalcifications. The sensitivity of the CAD system for second MLO views was 68% (45/66) for masses and 17% (6/35) for microcalcifications. In 84 ipsilateral serial MLO image sets (two patients had bilateral cancers), identical images, regardless of the existence of CAD marks, were obtained for 35% (29/84) and identical images with CAD marks were obtained for 29% (23/78). Identical images, regardless of the existence of CAD marks, for contralateral MLO images were 65% (52/80) and identical images with CAD marks were obtained for 28% (11/39). The reproducibility of CAD marks for the true positive masses in serial MLO views was 84% (42/50) and that for the true positive microcalcifications was 0% (0/34). The CAD system in digital mammograms showed a high sensitivity for detecting masses and microcalcifications. However, reproducibility of microcalcification marks was very low in MLO views taken serially without release of breast compression. Minute positional change and patient movement can alter the images and result in a significant effect on the algorithm utilized by the CAD for detecting microcalcifications

  12. Amoralist rationalism? A response to Joel Marks: commentary on "Animal abolitionism meets moral abolitionism: cutting the Gordian knot of applied ethics" by Joel Marks.

    Science.gov (United States)

    Lederman, Zohar

    2014-06-01

    In a recent article, Joel Marks presents the amoralist argument against vivisection, or animal laboratory experimentation. He argues that ethical theories that seek to uncover some universal morality are in fact useless and unnecessary for ethical deliberations meant to determine what constitutes an appropriate action in a specific circumstance. I agree with Marks' conclusion. I too believe that vivisection is indefensible, both from a scientific and philosophical perspective. I also believe that we should become vegan (unfortunately, like the two philosophers mentioned by Marks, I too am still struggling to reduce my meat and dairy consumption). However, I am in the dark as to Marks' vision of normative deliberations in the spirit of amoralism and desirism.

  13. Revised Mark 22 coolant temperature coefficients

    International Nuclear Information System (INIS)

    Graves, W.E.

    1987-01-01

    Coolant temperature coefficients for the Mark 22 charge published previously are non-conservative because of the neglect of a significant mechanism which has a positive contribution to reactivity. Even after correcting for this effect, dynamic tests made on a Mark VIB charge in the early 60's suggest the results are still non-conservative. This memorandum takes both of these sources of information into account in making a best estimate of the prompt (coolant plus metal) temperature coefficient. Although no safety issues arise from this work (the overall temperature coefficient still strongly contributes to reactor stability), it is obviously desirable to use best estimates for prompt coefficients in limits and other calculations

  14. Automatic data-processing equipment of moon mark of nail for verifying some experiential theory of Traditional Chinese Medicine.

    Science.gov (United States)

    Niu, Renjie; Fu, Chenyu; Xu, Zhiyong; Huang, Jianyuan

    2016-04-29

    Doctors who practice Traditional Chinese Medicine (TCM) diagnose using four methods - inspection, auscultation and olfaction, interrogation, and pulse feeling/palpation. The shape and shape changes of the moon marks on the nails are an important indication when judging the patient's health. There are a series of classical and experimental theories about moon marks in TCM, which does not have support from statistical data. To verify some experiential theories on moon mark in TCM by automatic data-processing equipment. This paper proposes the equipment that utilizes image processing technology to collect moon mark data of different target groups conveniently and quickly, building a database that combines this information with that gathered from the health and mental status questionnaire in each test. This equipment has a simple design, a low cost, and an optimized algorithm. The practice has been proven to quickly complete automatic acquisition and preservation of key data about moon marks. In the future, some conclusions will likely be obtained from these data; some changes of moon marks related to a special pathological change will be established with statistical methods.

  15. 22 CFR 226.91 - Marking.

    Science.gov (United States)

    2010-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Miscellaneous § 226.91 Marking. (a) USAID policy is that all programs, projects, activities... support of the American people through the United States Agency for International Development (USAID). The...

  16. Problems with ink skin markings for radiation field setups

    International Nuclear Information System (INIS)

    Endoh, Masaru; Saeki, Mituaki; Ishida, Yusei

    1982-01-01

    Ink skin markings are used in radiation therapy to aid in reproduction of treatment field setups or to indelibly outline field markings or tumors. We reported two cases of indelible ink skin for radiation field septa with minimal discomfort and dermatitis have been experienced for 6 months and above since end of radiotherapy. These indelible ink skin markings look like tattoo that will be big problems in the case of young female. We improved these problems by using of 10 percent silver nitrate instead of habitual skin ink. (author)

  17. Maaväline lind Mark Raidpere / Fagira D. Morti

    Index Scriptorium Estoniae

    Fagira D. Morti, pseud., 1974-

    2009-01-01

    Soome Vabariigi president Tarja Halonen andis 28. veebruaril 2009. aastal Kumu Kunstimuuseumis videokunstnik Mark Raidperele üle Ars Fennica kunstipreemia. Meenutusi kunstniku EHI-s õppimise ajast, esimese näituse "Ilo" avamisest Vaal galeriis. Mark Raidpere loomingu mõistmisest

  18. THE MARK I BUSINESS SYSTEM SIMULATION MODEL

    Science.gov (United States)

    of a large-scale business simulation model as a vehicle for doing research in management controls. The major results of the program were the...development of the Mark I business simulation model and the Simulation Package (SIMPAC). SIMPAC is a method and set of programs facilitating the construction...of large simulation models. The object of this document is to describe the Mark I Corporation model, state why parts of the business were modeled as they were, and indicate the research applications of the model. (Author)

  19. The Things of Caesar: Mark-ing the Plural (Mk 12:13–17

    Directory of Open Access Journals (Sweden)

    Warren Carter

    2014-09-01

    Full Text Available This article observes the rarely-discussed phenomenon that the Marcan paying-the-tax scene refers to tax in the singular, whilst the concluding saying uses the plural ‘the things of Caesar and of God’. The article accounts for this phenomenon by means of developing traditions. The section under the heading ‘Mark’s scene and saying about taxes (12:13–17’ counters the common claim that scene and saying originated as a unit from the historical Jesus. It proposes that whilst the saying may have originated with Jesus, the scene as we have it did not. The section under the heading ‘Social memory, orality, and a multi-referential saying?’ suggests some contexts that the saying about the things of Caesar addressed pre-Mark. And under the section ‘Trauma and Mark’s scene’ it is argued that Mark created a unit comprising scene and saying to negotiate the ‘ trauma’ of the 66–70 war. The unit evaluates freshly-asserted Roman power as idolatrous and blasphemous whilst simultaneously authorising the continued involvement of Jesus-believers in imperial society.

  20. Evaluation of TRIGA Mark II reactor in Turkey

    International Nuclear Information System (INIS)

    Bilge, Ali Nezihi

    1990-01-01

    There are two research reactors in Turkey and one of them is the university Triga Mark II reactor which was in service since 1979 both for education and industrial application purposes. The main aim of this paper is to evaluate the spectrum of the services carried by Turkish Triga Mark II reactor. In this work, statistical distribution of the graduate works and applications, by using Triga Mark II reactor is examined and evaluated. In addition to this, technical and scientific uses of this above mentioned reactor are also investigated. It was already showed that the uses and benefits of this reactor can not be limited. If the sufficient work and service is given, NDT and industrial applications can also be carried economically. (orig.)

  1. A Study on the Development of Playback Control Software for Mark5B VSI System

    Directory of Open Access Journals (Sweden)

    S. J. Oh

    2010-06-01

    Full Text Available We developed the playback control software for a high-speed playback system which is a component of the Korea-Japan Joint VLBI Correlator (KJJVC. The Mark5B system, which is a recorder and playback system used in the Korean VLBI Network (KVN, has two kinds of operation mode. That is to say, the station unit (SU mode, which is for the present Mark4 system, and the VSI mode, which is for the new VLBI standard interface (VSI system. The software for SU is already developed and widely used in the Mark4 type VLBI system, but the software for VSI has only been developed for recording. The new VLBI system is designed with a VSI interface for compatibility between different systems. Therefore, the playback control software development of the VSI mode is needed for KVN. In this work, we developed the playback control software of the Mark5B VSI mode. The developed playback control software consists of an application part for data playing back, a data input/output part for the VSI board, a module for the StreamStor RAID board, and a user interface part, including an observation time control part. To verify the performance of developed playback control software, the playback and correlation experiments were performed using the real observation data in Mark5B system and KJJVC. To check the observation time control, the data playback experiment was performed between the Mark5B and Raw VLBI Data Buffer (RVDB systems. Through the experimental results, we confirmed the performance of developed playback control software in the Mark5B VSI mode.

  2. An innovative road marking quality assessment mechanism using computer vision

    Directory of Open Access Journals (Sweden)

    Kuo-Liang Lin

    2016-06-01

    Full Text Available Aesthetic quality acceptance for road marking works has been relied on subjective visual examination. Due to a lack of quantitative operation procedures, acceptance outcome can be biased and results in great quality variation. To improve aesthetic quality acceptance procedure of road marking, we develop an innovative road marking quality assessment mechanism, utilizing machine vision technologies. Using edge smoothness as a quantitative aesthetic indicator, the proposed prototype system first receives digital images of finished road marking surface and has the images processed and analyzed to capture the geometric characteristics of the marking. The geometric characteristics are then evaluated to determine the quality level of the finished work. System is demonstrated through two real cases to show how it works. In the end, a test comparing the assessment results between the proposed system and expert inspection is conducted to enhance the accountability of the proposed mechanism.

  3. The Different Methods of Displacement Monitoring at Loading Tests of Bridges or Different Structures

    Directory of Open Access Journals (Sweden)

    Kovačič Boštjan

    2016-01-01

    Full Text Available By measuring the displacements and deformations at different structures we deal in the Faculty of Civil Engineering, transportation Engineering and Architecture in University of Maribor for about 20 years. At that time we measured over 600 structures. Most loading tests of bridges and Viaducts were made. The measurements of movements needed to be as precise and accurate as possible. To do that laboratory test of instruments were made to see which instrument gives us reliable results. Displacements can be determined by geodetic and physical methods, depends of the construction. The use of geodetic methods are still preferable. In the paper the measurements with the total station, the level and rotation level, photogrammetry and solutions on the field by physical methods with inductive transducers are presented. We need to measure displacements as quick as possible but efficiently because we can not repeat the measurements under the same conditions. Also the surveying on the bridge and in the lab with the comparison of methods is presented under the different hard terrain conditions - water beneath the construction, big height of the structure, unapproachability, large span structures.

  4. Use of rhodamine B to mark the body and seminal fluid of male Aedes aegypti for mark-release-recapture experiments and estimating efficacy of sterile male releases.

    Science.gov (United States)

    Johnson, Brian J; Mitchell, Sara N; Paton, Christopher J; Stevenson, Jessica; Staunton, Kyran M; Snoad, Nigel; Beebe, Nigel; White, Bradley J; Ritchie, Scott A

    2017-09-01

    Recent interest in male-based sterile insect technique (SIT) and incompatible insect technique (IIT) to control Aedes aegypti and Aedes albopictus populations has revealed the need for an economical, rapid diagnostic tool for determining dispersion and mating success of sterilized males in the wild. Previous reports from other insects indicated rhodamine B, a thiol-reactive fluorescent dye, administered via sugar-feeding can be used to stain the body tissue and seminal fluid of insects. Here, we report on the adaptation of this technique for male Ae. aegypti to allow for rapid assessment of competitiveness (mating success) during field releases. Marking was achieved by feeding males on 0.1, 0.2, 0.4 or 0.8% rhodamine B (w/v) in 50% honey solutions during free flight. All concentrations produced >95% transfer to females and successful body marking after 4 days of feeding, with 0.4 and 0.8% solutions producing the longest-lasting body marking. Importantly, rhodamine B marking had no effect on male mating competitiveness and proof-of-principle field releases demonstrated successful transfer of marked seminal fluid to females under field conditions and recapture of marked males. These results reveal rhodamine B to be a potentially useful evaluation method for male-based SIT/IIT control strategies as well as a viable body marking technique for male-based mark-release-recapture experiments without the negative side-effects of traditional marking methods. As a standalone method for use in mating competitiveness assays, rhodamine B marking is less expensive than PCR (e.g. paternity analysis) and stable isotope semen labelling methods and less time-consuming than female fertility assays used to assess competitiveness of sterilised males.

  5. Use of rhodamine B to mark the body and seminal fluid of male Aedes aegypti for mark-release-recapture experiments and estimating efficacy of sterile male releases.

    Directory of Open Access Journals (Sweden)

    Brian J Johnson

    2017-09-01

    Full Text Available Recent interest in male-based sterile insect technique (SIT and incompatible insect technique (IIT to control Aedes aegypti and Aedes albopictus populations has revealed the need for an economical, rapid diagnostic tool for determining dispersion and mating success of sterilized males in the wild. Previous reports from other insects indicated rhodamine B, a thiol-reactive fluorescent dye, administered via sugar-feeding can be used to stain the body tissue and seminal fluid of insects. Here, we report on the adaptation of this technique for male Ae. aegypti to allow for rapid assessment of competitiveness (mating success during field releases.Marking was achieved by feeding males on 0.1, 0.2, 0.4 or 0.8% rhodamine B (w/v in 50% honey solutions during free flight. All concentrations produced >95% transfer to females and successful body marking after 4 days of feeding, with 0.4 and 0.8% solutions producing the longest-lasting body marking. Importantly, rhodamine B marking had no effect on male mating competitiveness and proof-of-principle field releases demonstrated successful transfer of marked seminal fluid to females under field conditions and recapture of marked males.These results reveal rhodamine B to be a potentially useful evaluation method for male-based SIT/IIT control strategies as well as a viable body marking technique for male-based mark-release-recapture experiments without the negative side-effects of traditional marking methods. As a standalone method for use in mating competitiveness assays, rhodamine B marking is less expensive than PCR (e.g. paternity analysis and stable isotope semen labelling methods and less time-consuming than female fertility assays used to assess competitiveness of sterilised males.

  6. A comparative study between xerographic, computer-assisted overlay generation and animated-superimposition methods in bite mark analyses.

    Science.gov (United States)

    Tai, Meng Wei; Chong, Zhen Feng; Asif, Muhammad Khan; Rahmat, Rabiah A; Nambiar, Phrabhakaran

    2016-09-01

    This study was to compare the suitability and precision of xerographic and computer-assisted methods for bite mark investigations. Eleven subjects were asked to bite on their forearm and the bite marks were photographically recorded. Alginate impressions of the subjects' dentition were taken and their casts were made using dental stone. The overlays generated by xerographic method were obtained by photocopying the subjects' casts and the incisal edge outlines were then transferred on a transparent sheet. The bite mark images were imported into Adobe Photoshop® software and printed to life-size. The bite mark analyses using xerographically generated overlays were done by comparing an overlay to the corresponding printed bite mark images manually. In computer-assisted method, the subjects' casts were scanned into Adobe Photoshop®. The bite mark analyses using computer-assisted overlay generation were done by matching an overlay and the corresponding bite mark images digitally using Adobe Photoshop®. Another comparison method was superimposing the cast images with corresponding bite mark images employing the Adobe Photoshop® CS6 and GIF-Animator©. A score with a range of 0-3 was given during analysis to each precision-determining criterion and the score was increased with better matching. The Kruskal Wallis H test showed significant difference between the three sets of data (H=18.761, p<0.05). In conclusion, bite mark analysis using the computer-assisted animated-superimposition method was the most accurate, followed by the computer-assisted overlay generation and lastly the xerographic method. The superior precision contributed by digital method is discernible despite the human skin being a poor recording medium of bite marks. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Structures and mechanisms in clay nanopore trapping of structurally-different fluoroquinolone antimicrobials.

    Science.gov (United States)

    Okaikue-Woodi, Fanny E K; Kelch, Sabrina E; Schmidt, Michael P; Enid Martinez, Carmen; Youngman, Randall E; Aristilde, Ludmilla

    2018-03-01

    Smectite clay nanoparticles are implicated in the retention of antimicrobials within soils and sediments; these clays are also inspected as drug carriers in physiological systems. Cation exchange is considered the primary adsorption mechanism of antimicrobials within smectite nanopores. However, a dual role of acid-base chemistry and adsorptive structures is speculated by recent studies. Using the prototypical smectite clay montmorillonite, we employed a combination of X-ray diffraction (XRD), nuclear magnetic resonance, attenuated total reflectance-Fourier transform infrared spectroscopy, and molecular dynamics simulations to investigate the interlayer nanopore trapping of two structurally-different fluoroquinolone (FQ) antimicrobials with similar acid-base chemistry: ciprofloxacin (a first-generation FQ) and moxifloxacin (a third-generation FQ). Greater sorption at pH 5.0 than at pH 7.0 for both FQs was consistent with cation-exchange of positively-charged species. However, the clay exhibited a near twofold higher sorption capacity for moxifloxacin than for ciprofloxacin. This difference was shown by the XRD data to be accompanied by enhanced trapping of moxifloxacin within the clay interlayers. Using the XRD-determined nanopore sizes, we performed molecular dynamics simulations of thermodynamically-favorable model adsorbates, which revealed that ciprofloxacin was adsorbed parallel to the clay surface but moxifloxacin adopted a tilted conformation across the nanopore. These conformations resulted in more slowly-exchanged than quickly-exchanged Na complexes with ciprofloxacin compared with moxifloxacin. These different Na populations were also captured by 23 Na nuclear magnetic resonance. Furthermore, the simulated adsorbates uncovered different complexation interactions that were corroborated by infrared spectroscopy. Therefore, beyond acid-base chemistry, our findings imply that distinct adsorbate structures control antimicrobial trapping within clay nanopores

  8. Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids

    Energy Technology Data Exchange (ETDEWEB)

    Moravcevic, Katarina; Mendrola, Jeannine M.; Schmitz, Karl R.; Wang, Yu-Hsiu; Slochower, David; Janmey, Paul A.; Lemmon, Mark A. (UPENN-MED)

    2011-09-28

    Phospholipid-binding modules such as PH, C1, and C2 domains play crucial roles in location-dependent regulation of many protein kinases. Here, we identify the KA1 domain (kinase associated-1 domain), found at the C terminus of yeast septin-associated kinases (Kcc4p, Gin4p, and Hsl1p) and human MARK/PAR1 kinases, as a membrane association domain that binds acidic phospholipids. Membrane localization of isolated KA1 domains depends on phosphatidylserine. Using X-ray crystallography, we identified a structurally conserved binding site for anionic phospholipids in KA1 domains from Kcc4p and MARK1. Mutating this site impairs membrane association of both KA1 domains and intact proteins and reveals the importance of phosphatidylserine for bud neck localization of yeast Kcc4p. Our data suggest that KA1 domains contribute to coincidence detection, allowing kinases to bind other regulators (such as septins) only at the membrane surface. These findings have important implications for understanding MARK/PAR1 kinases, which are implicated in Alzheimer's disease, cancer, and autism.

  9. Prosodic Focus Marking in Bai.

    NARCIS (Netherlands)

    Liu, Zenghui; Chen, A.; Van de Velde, Hans

    2014-01-01

    This study investigates prosodic marking of focus in Bai, a Sino-Tibetan language spoken in the Southwest of China, by adopting a semi-spontaneous experimental approach. Our data show that Bai speakers increase the duration of the focused constituent and reduce the duration of the post-focus

  10. Full-Scale Mark II CRT Program data report, 1

    International Nuclear Information System (INIS)

    Namatame, Ken; Kukita, Yutaka; Yamamoto, Nobuo; Shiba, Masayoshi

    1979-12-01

    The Full-Scale Mark II CRT (Containment Response Test) Program was initiated in April 1976 to provide a full-scale data basis for the evaluation of the pressure suppression pool hydrodynamic loads associated with a hypothetical LOCA in a BWR Mark II Containment. The test facility, completed in March 1979, is 1/18 in volume of a typical 1100 MWe Mark II, and has a wetwell which is a full-scale replica of one 20 0 -sector of that of the reference Mark II. The present report documents experimental data from TEST 0002, a medium size (100 mm) water blowdown test, performed by Hitachi Ltd. for JAERI as the second of the four shakedown tests. Test data is provided for the vessel depressurization, the pressure and temperature responses in the test containment, and especially for the chugging phenomena associated with low flux steam condensation in the pool. (author)

  11. 49 CFR 180.213 - Requalification markings.

    Science.gov (United States)

    2010-10-01

    ... eddy current examination combined with a visual inspection, the marking is as illustrated in paragraph..., securely affixed in a manner prescribed by the cylinder manufacturer, near the original manufacturer's...

  12. Laser marking as a result of applying reverse engineering

    Science.gov (United States)

    Mihalache, Andrei; Nagîţ, Gheorghe; Rîpanu, Marius Ionuţ; Slǎtineanu, Laurenţiu; Dodun, Oana; Coteaţǎ, Margareta

    2018-05-01

    The elaboration of a modern manufacturing technology needs a certain quantum of information concerning the part to be obtained. When it is necessary to elaborate the technology for an existing object, such an information could be ensured by using the principles specific to the reverse engineering. Essentially, in the case of this method, the analysis of the surfaces and of other characteristics of the part must offer enough information for the elaboration of the part manufacturing technology. On the other hand, it is known that the laser marking is a processing method able to ensure the transfer of various inscriptions or drawings on a part. Sometimes, the laser marking could be based on the analysis of an existing object, whose image could be used to generate the same object or an improved object. There are many groups of factors able to affect the results of applying the laser marking process. A theoretical analysis was proposed to show that the heights of triangles obtained by means of a CNC marking equipment depend on the width of the line generated by the laser spot on the workpiece surface. An experimental research was thought and materialized to highlight the influence exerted by the line with and the angle of lines intersections on the accuracy of the marking process. By mathematical processing of the experimental results, empirical mathematical models were determined. The power type model and the graphical representation elaborated on the base of this model offered an image concerning the influences exerted by the considered input factors on the marking process accuracy.

  13. Difference analysis for fluid-structure interaction

    International Nuclear Information System (INIS)

    Giencke, E.; Forkel, M.

    1979-01-01

    For solving fluid structure interaction problems it is possible to organize the compter programs for the difference method in the same way as for the finite element method by establishing the difference equations with the principial of virtual work. In the finite element method the individual localized functions for the approximation of the potential function PHI will be chosen also as virtual functions delta PHI. Deriving difference equations the virtual states are simple as possible and the approximation of the potential function may be linear or parabolic. The equations become symmetric both for points in the interiour and the boundaries and for grids with rectangular and triangular elements. The boundary and edge-conditions shall established for elastic walls and for the free surface. For regular rectangular and triangular grids it is possible to derive on the same way multipoint difference equations, which for the same numbers of unknowns are two orders better in accuracy as the usual difference or the finite element equations. Some examples for the pressure distribution in a BWR-steel-containment due to steam bubble collaps at the condenser pipes will be shown. (orig.)

  14. Regulation of glucose homeostasis by KSR1 and MARK2.

    Directory of Open Access Journals (Sweden)

    Paula J Klutho

    Full Text Available Protein scaffolds control the intensity and duration of signaling and dictate the specificity of signaling through MAP kinase pathways. KSR1 is a molecular scaffold of the Raf/MEK/ERK MAP kinase cascade that regulates the intensity and duration of ERK activation. Relative to wild-type mice, ksr1⁻/⁻ mice are modestly glucose intolerant, but show a normal response to exogenous insulin. However, ksr1⁻/⁻ mice also demonstrate a three-fold increase in serum insulin levels in response to a glucose challenge, suggesting a role for KSR1 in insulin secretion. The kinase MARK2 is closely related to C-TAK1, a known regulator of KSR1. Mice lacking MARK2 have an increased rate of glucose disposal in response to exogenous insulin, increased glucose tolerance, and are resistant to diet-induced obesity. mark2⁻/⁻ksr1⁻/⁻ (DKO mice were compared to wild type, mark2⁻/⁻, and ksr1⁻/⁻ mice for their ability to regulate glucose homeostasis. Here we show that disruption of KSR1 in mark2⁻/⁻ mice reverses the increased sensitivity to exogenous insulin resulting from MARK2 deletion. DKO mice respond to exogenous insulin similarly to wild type and ksr1⁻/⁻ mice. These data suggest a model whereby MARK2 negatively regulates insulin sensitivity in peripheral tissue through inhibition of KSR1. Consistent with this model, we found that MARK2 binds and phosphorylates KSR1 on Ser392. Phosphorylation of Ser392 is a critical regulator of KSR1 stability, subcellular location, and ERK activation. These data reveal an unexpected role for the molecular scaffold KSR1 in insulin-regulated glucose metabolism.

  15. Midwifery students' evaluation of team-based academic assignments involving peer-marking.

    Science.gov (United States)

    Parratt, Jenny A; Fahy, Kathleen M; Hastie, Carolyn R

    2014-03-01

    Midwives should be skilled team workers in maternity units and in group practices. Poor teamwork skills are a significant cause of adverse maternity care outcomes. Despite Australian and International regulatory requirements that all midwifery graduates are competent in teamwork, the systematic teaching and assessment of teamwork skills is lacking in higher education. How do midwifery students evaluate participation in team-based academic assignments, which include giving and receiving peer feedback? First and third year Bachelor of Midwifery students who volunteered (24 of 56 students). Participatory Action Research with data collection via anonymous online surveys. There was general agreement that team based assignments; (i) should have peer-marking, (ii) help clarify what is meant by teamwork, (iii) develop communication skills, (iv) promote student-to-student learning. Third year students strongly agreed that teams: (i) are valuable preparation for teamwork in practice, (ii) help meet Australian midwifery competency 8, and (iii) were enjoyable. The majority of third year students agreed with statements that their teams were effectively coordinated and team members shared responsibility for work equally; first year students strongly disagreed with these statements. Students' qualitative comments substantiated and expanded on these findings. The majority of students valued teacher feedback on well-developed drafts of the team's assignment prior to marking. Based on these findings we changed practice and created more clearly structured team-based assignments with specific marking criteria. We are developing supporting lessons to teach specific teamwork skills: together these resources are called "TeamUP". TeamUP should be implemented in all pre-registration Midwifery courses to foster students' teamwork skills and readiness for practice. Copyright © 2013 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  16. Marked variation in newborn resuscitation practice: A national survey in the UK☆

    Science.gov (United States)

    Mann, Chantelle; Ward, Carole; Grubb, Mark; Hayes-Gill, Barrie; Crowe, John; Marlow, Neil; Sharkey, Don

    2012-01-01

    Background Although international newborn resuscitation guidance has been in force for some time, there are no UK data on current newborn resuscitation practices. Objective Establish delivery room (DR) resuscitation practices in the UK, and identify any differences between neonatal intensive care units (NICU), and other local neonatal services. Methods We conducted a structured two-stage survey of DR management, among UK neonatal units during 2009–2010 (n = 192). Differences between NICU services (tertiary level) and other local neonatal services (non-tertiary) were analysed using Fisher's exact and Student's t-tests. Results There was an 89% response rate (n = 171). More tertiary NICUs institute DR CPAP than non-tertiary units (43% vs. 16%, P = 0.0001) though there was no significant difference in frequency of elective intubation and surfactant administration for preterm babies. More tertiary units commence DR resuscitation in air (62% vs. 29%, P < 0.0001) and fewer in 100% oxygen (11% vs. 41%, P < 0.0001). Resuscitation of preterm babies in particular, commences with air in 56% of tertiary units. Significantly more tertiary units use DR pulse oximeters (58% vs. 29%, P < 0.01) and titrate oxygen based on saturations. Almost all services use occlusive wrapping to maintain temperature for preterm infants. Conclusions In the UK, there are many areas of good evidence based DR practice. However, there is marked variation in management, including between units of different designation, suggesting a need to review practice to fulfil new resuscitation guidance, which will have training and resource implications. PMID:22245743

  17. 9 CFR 592.340 - Supervision of marking and packaging.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... evidence that such official identification or packaging material bearing such official identification has...

  18. 76 FR 11432 - Coding of Design Marks in Registrations

    Science.gov (United States)

    2011-03-02

    ...] Coding of Design Marks in Registrations AGENCY: United States Patent and Trademark Office, Commerce... practice of coding newly registered trademarks that include a design element with design mark codes based... notice and request for comments at 75 FR 81587, proposing to discontinue a secondary system of coding...

  19. Myoglobin solvent structure at different temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Daniels, B.V.; Korszun, Z.R. [Brookhaven National Laboratory, Upton, NY (United States); Schoenborn, B.P. [Los Alamos National Laboratory, NM (United States)

    1994-12-31

    The structure of the solvent surrounding myoglobin crystals has been analyzed using neutron diffraction data, and the results indicate that the water around the protein is not disordered, but rather lies in well-defined hydration shells. We have analyzed the structure of the solvent surrounding the protein by collecting neutron diffraction data at four different temperatures, namely, 80, 130, 180, and 240K. Relative Wilson Statistics applied to low resolution data showed evidence of a phase transition in the region of 180K. A plot of the liquidity factor, B{sub sn}, versus distance from the protein surface begins with a high plateau near the surface of the protein and drops to two minima at distances from the protein surface of about 2.35{Angstrom} and 3.85{Angstrom}. Two distinct hydration shells are observed. Both hydration shells are observed to expand as the temperature is increased.

  20. Myoglobin solvent structure at different temperatures

    International Nuclear Information System (INIS)

    Daniels, B.V.; Korszun, Z.R.; Schoenborn, B.P.

    1994-01-01

    The structure of the solvent surrounding myoglobin crystals has been analyzed using neutron diffraction data, and the results indicate that the water around the protein is not disordered, but rather lies in well-defined hydration shells. We have analyzed the structure of the solvent surrounding the protein by collecting neutron diffraction data at four different temperatures, namely, 80, 130, 180, and 240K. Relative Wilson Statistics applied to low resolution data showed evidence of a phase transition in the region of 180K. A plot of the liquidity factor, B sn , versus distance from the protein surface begins with a high plateau near the surface of the protein and drops to two minima at distances from the protein surface of about 2.35 Angstrom and 3.85 Angstrom. Two distinct hydration shells are observed. Both hydration shells are observed to expand as the temperature is increased

  1. Group marking and peer assessment during a group poster presentation: the experiences and views of midwifery students.

    Science.gov (United States)

    Ohaja, Magdalena; Dunlea, Margaret; Muldoon, Kathryn

    2013-09-01

    Traditionally, written examination and clinical practice assessments are the main ways of deeming midwifery students fit and competent for practice. Contemporary academics in an effort to engage the students in the learning process have employed alternative teaching and assessment strategies. Among the alternative strategies are group projects after which members of the group are awarded the same grade, and peer assessment. With the purpose of informing the midwifery curricular, we utilised a qualitative descriptive approach to explore midwifery students' experiences and views on the use of group poster presentation for learning and assessment. The participants consisted of a purposive sample of 14 higher diploma midwifery students who were registered in a third level institution in Ireland. Semi-structured individual interviews were conducted following the completion of the poster presentation assessment. Permission to undertake the study was obtained from the college ethics committee. In this paper, we focus on the participants' views of group marking and peer assessment which are among the key elements that emerged in this study. While awarding a group mark was overall accepted, peer assessment proved a more contentious issue. Most of the participants found it challenging marking their friends. Reactions to group marks were very much influenced by the group dynamics. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Inlfuence of Different-Frequency Glucocorticoid Induction on Morphological Structures of Humeri, Soft Tissues and Immune System in Rats

    Institute of Scientific and Technical Information of China (English)

    LI Jian-min; LI Heng

    2016-01-01

    Objective: To explore the influence of different-frequency glucocorticoid (GC) induction on morphological structures of humeri and soft tissues as well as immune system in rats. Methods: A total of 32 speciifc pathogen-free (SPF) SD rats at the age of 3 months were selected and randomly divided into 4 groups, 8 cases in each group. The rats in control group were not given any treatment, while those in low-, moderate- and high-frequency groups were treated with intramuscular injection of dexamethasone 1 mg/kg per time for twice, 4 times and 6 times per week, respectively. All the rats were sacriifced on d30 to measure their body mass and qualities of soft tissues and immune organs, and bone histomorphometry was applied to analyze humeral bone mass and bone structural changes. Results: Compared with control group, there was no change in cancellous bone mass and bone structures of upper humeri in low-frequency group, but serious loss of bone mass, signiifcantly degenerated bone structure, markedly reduced trabecular thickness and number as well as notably increased trabecular separation was all observed in moderate- and high-frequency groups. The size of cortical bones, total size of bone structure, thickness of cortical bones and size percentage of cortical bones in middle humeri reduced apparently, while the size percentage of medullary cavity increased dramatically in high-frequency group. Growth plate thickness of upper humeri decreased in low-, moderate- and high-frequency groups, and the diameters of mastocytes diminished in moderate- and high-frequency groups. Compared with control group, body mass decreased obviously, qualities and indexes of spleen and thymus showed decreasing tendency along with the increase of drug administration frequency in low-, moderate- and high-frequency groups. Conclusion: Low-frequency GC cannot change humeral morphology. The higher the frequency of drug administration is, the more the loss of cancellous bone mass is. When the

  3. The efficacy of mass-marking channel catfish fingerlings by immersion in oxytetracycline

    Science.gov (United States)

    Stewart, David R.

    2011-01-01

    Oxytetracycline (OTC) has been extensively used for marking a variety of fish species, but has never been successfully used to mark channel catfish Ictalurus punctatus. Channel catfish fingerlings (~ 25 mm TL) obtained from the Oklahoma Department of Wildlife Conservation at Byron Fish Hatchery were kept in Living Streams (791 to 1,018 L) equipped with recirculation units. Marking trials consisted of immersing channel catfish in one of three concentrations (250, 450, and 700 mg/L) OTC hydrochloride [HCl] for 6 hours. Samples of channel catfish were obtained from each group at 1-week and 4-week postimmersion. Lapilli otoliths and pectoral spines were removed to assess mark presence with an epi-fluorescent compound microscope. After one week, no marks were detected on pectoral spines for all treatments, mark detection on otoliths depended on concentration, but never exceeded 43% (700 mg/L). After four weeks, all otoliths and pectoral spines were determined marked for 700 mg/L OTC, 20% for fish immersed in 450 mg/L OTC, and 0% were marked after four weeks at the 250 mg/L OTC. Results show, channel catfish fingerlings can be successfully marked with immersion in OTC at 700 mg/L for at least 6 hours.

  4. Phylogeography of the common vampire bat (Desmodus rotundus: Marked population structure, Neotropical Pleistocene vicariance and incongruence between nuclear and mtDNA markers

    Directory of Open Access Journals (Sweden)

    Morgante João S

    2009-12-01

    Full Text Available Abstract Background The common vampire bat Desmodus rotundus is an excellent model organism for studying ecological vicariance in the Neotropics due to its broad geographic range and its preference for forested areas as roosting sites. With the objective of testing for Pleistocene ecological vicariance, we sequenced a mitocondrial DNA (mtDNA marker and two nuclear markers (RAG2 and DRB to try to understand how Pleistocene glaciations affected the distribution of intraspecific lineages in this bat. Results Five reciprocally monophyletic clades were evident in the mitochondrial gene tree, and in most cases with high bootstrap support: Central America (CA, Amazon and Cerrado (AMC, Pantanal (PAN, Northern Atlantic Forest (NAF and Southern Atlantic Forest (SAF. The Atlantic forest clades formed a monophyletic clade with high bootstrap support, creating an east/west division for this species in South America. On the one hand, all coalescent and non-coalescent estimates point to a Pleistocene time of divergence between the clades. On the other hand, the nuclear markers showed extensive sharing of haplotypes between distant localities, a result compatible with male-biased gene flow. In order to test if the disparity between the mitochondrial and nuclear markers was due to the difference in mutation rate and effective size, we performed a coalescent simulation to examine the feasibility that, given the time of separation between the observed lineages, even with a gene flow rate close to zero, there would not be reciprocal monophyly for a neutral nuclear marker. We used the observed values of theta and an estimated mutation rate for the nuclear marker gene to perform 1000 iterations of the simulation. The results of this simulation were inconclusive: the number of iterations with and without reciprocal monophyly of one or more clades are similar. Conclusions We therefore conclude that the pattern exhibited by the common vampire bat, with marked

  5. DEMAND FOR AND SUPPLY OF MARK-UP AND PLS FUNDS IN ISLAMIC BANKING: SOME ALTERNATIVE EXPLANATIONS

    OpenAIRE

    KHAN, TARIQULLAH

    1995-01-01

    Profit and loss-sharing (PLS) and bai’ al murabahah lil amir bil shira (mark-up) are the two parent principles of Islamic financing. The use of PLS is limited and that of mark-up overwhelming in the operations of the Islamic banks. Several studies provide different explanations for this phenomenon. The dominant among these is the moral hazard hypothesis. Some alternative explanations are given in the present paper. The discussion is based on both demand (user of funds) and supply (bank) side ...

  6. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Former St. Marks Refinery in St. Marks, Florida

    Energy Technology Data Exchange (ETDEWEB)

    Lisell, L.; Mosey, G.

    2010-09-01

    This report presents the results of an assessment of the technical and economic feasibility of deploying a photovoltaics (PV) system on a brownfield site in St. Marks, Florida. The site was assessed for possible PV installations. The cost, performance, and site impacts of different PV options were estimated. The economics of the potential systems were analyzed using an electric rate of $0.08/kWh and incentives offered in the State of Florida and from the two accessible utilities, Progress Energy and the City of Tallahassee. According to the site production calculations, the most cost-effective system in terms of return on investment is the fixed-tilt thin film technology. The report recommends financing options that could assist in the implementation of such a system.

  7. A Study on introduction of Bench Marking in the power industry - concentrated on the Bench Marking issue in the power industry

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyuck Soo [Korea Energy Economics Institute, Euiwang (Korea)

    1998-08-01

    Recently it takes too much pains for enterprises to be adapted to the more complicated social structure. There are no guarantees to survive in competition only with improving service quality of a product, reducing cost by improving production efficiency, and reducing labors. To survive in a keen competition, it is important to acquire new management techniques and management theories. Among them, a benchmarking technique, improving competitive power through the analysis of top-ranking companies or companies with excellent results in a comparative sector, is in the spotlight recently. Therefore, the approaches to bench marking were discussed with the focus on the adaptation of KEPCO with a new paradigm. However, this study contained the limit of applying benchmarking technique due to its huge scale. Therefore, it was focused on brining up benchmarking issue by reflecting the basic problems of power industry to the developed countries. (author). 29 refs., 16 figs., 41 tabs.

  8. Automatic extraction of pavement markings on streets from point cloud data of mobile LiDAR

    International Nuclear Information System (INIS)

    Gao, Yang; Zhong, Ruofei; Liu, Xianlin; Tang, Tao; Wang, Liuzhao

    2017-01-01

    Pavement markings provide an important foundation as they help to keep roads users safe. Accurate and comprehensive information about pavement markings assists the road regulators and is useful in developing driverless technology. Mobile light detection and ranging (LiDAR) systems offer new opportunities to collect and process accurate pavement markings’ information. Mobile LiDAR systems can directly obtain the three-dimensional (3D) coordinates of an object, thus defining spatial data and the intensity of (3D) objects in a fast and efficient way. The RGB attribute information of data points can be obtained based on the panoramic camera in the system. In this paper, we present a novel method process to automatically extract pavement markings using multiple attribute information of the laser scanning point cloud from the mobile LiDAR data. This method process utilizes a differential grayscale of RGB color, laser pulse reflection intensity, and the differential intensity to identify and extract pavement markings. We utilized point cloud density to remove the noise and used morphological operations to eliminate the errors. In the application, we tested our method process on different sections of roads in Beijing, China, and Buffalo, NY, USA. The results indicated that both correctness ( p ) and completeness ( r ) were higher than 90%. The method process of this research can be applied to extract pavement markings from huge point cloud data produced by mobile LiDAR. (paper)

  9. Automatic extraction of pavement markings on streets from point cloud data of mobile LiDAR

    Science.gov (United States)

    Gao, Yang; Zhong, Ruofei; Tang, Tao; Wang, Liuzhao; Liu, Xianlin

    2017-08-01

    Pavement markings provide an important foundation as they help to keep roads users safe. Accurate and comprehensive information about pavement markings assists the road regulators and is useful in developing driverless technology. Mobile light detection and ranging (LiDAR) systems offer new opportunities to collect and process accurate pavement markings’ information. Mobile LiDAR systems can directly obtain the three-dimensional (3D) coordinates of an object, thus defining spatial data and the intensity of (3D) objects in a fast and efficient way. The RGB attribute information of data points can be obtained based on the panoramic camera in the system. In this paper, we present a novel method process to automatically extract pavement markings using multiple attribute information of the laser scanning point cloud from the mobile LiDAR data. This method process utilizes a differential grayscale of RGB color, laser pulse reflection intensity, and the differential intensity to identify and extract pavement markings. We utilized point cloud density to remove the noise and used morphological operations to eliminate the errors. In the application, we tested our method process on different sections of roads in Beijing, China, and Buffalo, NY, USA. The results indicated that both correctness (p) and completeness (r) were higher than 90%. The method process of this research can be applied to extract pavement markings from huge point cloud data produced by mobile LiDAR.

  10. Continuous assessment and matriculation examination marks – An empirical examination

    Directory of Open Access Journals (Sweden)

    Servaas van der Berg

    2015-12-01

    This study compares CASS data to the externally assessed matric exam marks for a number of subjects. There are two signalling dimensions to inaccurate assessments: (i Inflated CASS marks can give students a false sense of security and lead to diminished exam effort. (ii A weak correlation between CASS and the exam marks could mean poor signalling in another dimension: Relatively good students may get relatively low CASS marks. Such low correlations indicate poor assessment reliability, as the examination and continuous assessment should both be testing mastery of the same national curriculum. The paper analyses the extent of each of these dimensions of weak signalling in South African schools and draws disturbing conclusions for a large part of the school system.

  11. 9 CFR 316.12 - Marking of equine carcasses and parts thereof.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of equine carcasses and parts... equine carcasses and parts thereof. (a) All inspected and passed equine carcasses and parts thereof... marking products in this part. (b) All equine carcasses and meat and other parts thereof shall be marked...

  12. Mark Twain, Fenimore Cooper, and Batman.

    Science.gov (United States)

    Crick, Robert Alan

    1992-01-01

    Describes how Mark Twain's essay "Fenimore Cooper's Literary Offenses" helped students to get interested in writing and inspired them to write a similar essay critiquing the movie "Batman." Provides excerpts from students' essays. (PRA)

  13. Comparison of a ZGP OPO with a Mark-III FEL as a Potential Replacement for Mid-Infrared Soft Tissue Ablation Applications

    CERN Document Server

    Mackanos, M A

    2005-01-01

    A Mark-III FEL, tuned to 6.45 μm has demonstrated minimal collateral damage and high ablation yield in soft tissue. Further clinical advances are limited due to the overhead associated with an FEL; alternative mid-IR sources are needed. The FEL parameters needed to carry out efficient ablation with minimal damage must be determined. Studies by this author have shown that the unique pulse structure of the FEL does not play a role in this process [1]. We focused on comparing the macropulse duration of the FEL with a ZGP-OPO. No difference in pulse structure between the two laser sources with respect to the ablation threshold of water and mouse dermis was seen. There is a difference between the sources with respect to the crater depths in gelatin and mouse dermis. At 6.1 μm, the OPO craters are 8 times the depth of the FEL ones. Brightfield imaging shows the classic ablation mechanism. The timescale of the crater formation, ejection, and collapse occurs on a faster scale for the OPO. Histology ...

  14. Nonlinear dynamic analysis of framed structures including soil-structure interaction effects

    International Nuclear Information System (INIS)

    Mahmood, M.N.; Ahmed, S.Y.

    2008-01-01

    The role of oil-structure interaction on seismic behavior of reinforced concrete structures is investigated in this paper. A finite element approach has been adopted to model the interaction system that consists of the reinforced concrete plane frame, soil deposit and interface which represents the frictional between foundation of the structure and subsoil. The analysis is based on the elasto-plastic behavior of the frame members (beams and columns) that is defined by the ultimate axial force-bending moment interaction curve, while the cap model is adopted to govern the elasto-plastic behavior of the soil material. Mohr-Coulomb failure law is used to determine the initiation of slippage at the interface, while the separation is assumed to determine the initiation of slippage at the interface, while the separation is assumed to occur when the stresses at the interface becomes tension stresses. New-Mark's Predictor-Corrector algorithm is adopted for nonlinear dynamic analysis. The main aim of present work is to evaluate the sensitivity of structures to different behavior of the soil and interface layer when subjected to an earthquake excitation. Predicted results of the dynamic analysis of the interaction system indicate that the soil-structure interaction problem can have beneficial effects on the structural behavior when different soil models (elastic and elasto-plastic) and interface conditions (perfect bond and permitted slip)are considered. (author)

  15. Microbial analysis of bite marks by sequence comparison of streptococcal DNA.

    Directory of Open Access Journals (Sweden)

    Darnell M Kennedy

    Full Text Available Bite mark injuries often feature in violent crimes. Conventional morphometric methods for the forensic analysis of bite marks involve elements of subjective interpretation that threaten the credibility of this field. Human DNA recovered from bite marks has the highest evidentiary value, however recovery can be compromised by salivary components. This study assessed the feasibility of matching bacterial DNA sequences amplified from experimental bite marks to those obtained from the teeth responsible, with the aim of evaluating the capability of three genomic regions of streptococcal DNA to discriminate between participant samples. Bite mark and teeth swabs were collected from 16 participants. Bacterial DNA was extracted to provide the template for PCR primers specific for streptococcal 16S ribosomal RNA (16S rRNA gene, 16S-23S intergenic spacer (ITS and RNA polymerase beta subunit (rpoB. High throughput sequencing (GS FLX 454, followed by stringent quality filtering, generated reads from bite marks for comparison to those generated from teeth samples. For all three regions, the greatest overlaps of identical reads were between bite mark samples and the corresponding teeth samples. The average proportions of reads identical between bite mark and corresponding teeth samples were 0.31, 0.41 and 0.31, and for non-corresponding samples were 0.11, 0.20 and 0.016, for 16S rRNA, ITS and rpoB, respectively. The probabilities of correctly distinguishing matching and non-matching teeth samples were 0.92 for ITS, 0.99 for 16S rRNA and 1.0 for rpoB. These findings strongly support the tenet that bacterial DNA amplified from bite marks and teeth can provide corroborating information in the identification of assailants.

  16. Nõmme maja "Kergus" : Kerese tn., Tallinn / Ülar Mark, Kalle Komissarov

    Index Scriptorium Estoniae

    Mark, Ülar

    1999-01-01

    Kahekorruselise, tänavapoolse pika umbse seinaga eramu projekteeris Arhitektuuribüroo Mark & Tamm, arhitekt Ülar Mark, kaasautor Kalle Komissarov. Konstruktiivne osa: Randväli & Karema Inseneribüroo. Projekt 1997, hoone valmis 1999. Eramu tähenduse ümbermõtestamisest. 13 illustratsiooni: korruste plaanid, välisvaated, sisevaade.Mark & Tamm (arhitektibüroo)

  17. 27 CFR 26.207 - Destruction of marks and brands.

    Science.gov (United States)

    2010-04-01

    ... brands. 26.207 Section 26.207 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Products Coming Into the United States From the Virgin Islands § 26.207 Destruction of marks and brands. The marks, brands, and serial numbers required by this part to be placed on barrels, casks, or similar...

  18. 27 CFR 26.41 - Destruction of marks and brands.

    Science.gov (United States)

    2010-04-01

    ... brands. 26.41 Section 26.41 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Products Coming Into the United States From Puerto Rico § 26.41 Destruction of marks and brands. The marks, brands, and serial numbers required by this part to be placed on barrels, casks, or similar containers...

  19. 15 CFR 16.10 - The Department of Commerce Mark.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false The Department of Commerce Mark. 16.10 Section 16.10 Commerce and Foreign Trade Office of the Secretary of Commerce PROCEDURES FOR A VOLUNTARY CONSUMER PRODUCT INFORMATION LABELING PROGRAM § 16.10 The Department of Commerce Mark. The Department of...

  20. Size matters at deep-sea hydrothermal vents: different diversity and habitat fidelity patterns of meio- and macrofauna

    NARCIS (Netherlands)

    Gollner, S.; Govenar, B.; Fisher, C.R.; Bright, M.

    2015-01-01

    Species with markedly different sizes interact when sharing the same habitat. Unravelling mechanisms that control diversity thus requires consideration of a range of size classes. We compared patterns of diversity and community structure for meio- and macrofaunal communities sampled along a gradient

  1. 27 CFR 22.33 - Time of destruction of marks and brands.

    Science.gov (United States)

    2010-04-01

    ... marks and brands. 22.33 Section 22.33 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... Provisions Destruction of Marks and Brands § 22.33 Time of destruction of marks and brands. (a) Any person..., brand, and labels required by this chapter to be placed on packages of tax-free alcohol. (b) A person...

  2. Quantum Query Complexity for Searching Multiple Marked States from an Unsorted Database

    International Nuclear Information System (INIS)

    Shang Bin

    2007-01-01

    An important and usual sort of search problems is to find all marked states from an unsorted database with a large number of states. Grover's original quantum search algorithm is for finding single marked state with uncertainty, and it has been generalized to the case of multiple marked states, as well as been modified to find single marked state with certainty. However, the query complexity for finding all multiple marked states has not been addressed. We use a generalized Long's algorithm with high precision to solve such a problem. We calculate the approximate query complexity, which increases with the number of marked states and with the precision that we demand. In the end we introduce an algorithm for the problem on a 'duality computer' and show its advantage over other algorithms.

  3. Evaluation of soil-structure interaction for structures subjected to earthquake loading with different types of foundation

    Directory of Open Access Journals (Sweden)

    Elwi Mohammed

    2018-01-01

    Full Text Available However though the structures are supported on soil, most of the designers do not consider the soil structure interaction and its subsequent effect on structure during an earthquake. Different soil properties can affect seismic waves as they pass through a soil layer. When a structure is subjected to an earthquake excitation, it interacts the foundation and soil, and thus changes the motion of the ground. It means that the movement of the whole ground structure system is influenced by type of soil as well as by the type of structure. Tall buildings are supposed to be of engineered construction in sense that they might have been analyzed and designed to meet the provision of relevant codes of practice and building bye-laws. IS 1893: 2002 “Criteria for Earthquake Resistant Design of Structures” gives response spectrum for different types of soil such as hard, medium and soft. An attempt has been made in this paper to study the effect of Soil-structure interaction on multi storeyed buildings with various foundation systems. Also to study the response of buildings subjected to seismic forces with Rigid and Flexible foundations. Multi storeyed buildings with fixed and flexible support subjected to seismic forces were analyzed under different soil conditions like hard, medium and soft. The buildings were analyzed by Response spectrum method using software SAP2000. The response of building frames such as Lateral deflection, Story drift, Base shear, Axial force and Column moment values for all building frames were presented in this paper.

  4. Soil-borne microbial functional structure across different land uses.

    Science.gov (United States)

    Kuramae, Eiko E; Zhou, Jizhong Z; Kowalchuk, George A; van Veen, Johannes A

    2014-01-01

    Land use change alters the structure and composition of microbial communities. However, the links between environmental factors and microbial functions are not well understood. Here we interrogated the functional structure of soil microbial communities across different land uses. In a multivariate regression tree analysis of soil physicochemical properties and genes detected by functional microarrays, the main factor that explained the different microbial community functional structures was C : N ratio. C : N ratio showed a significant positive correlation with clay and soil pH. Fields with low C : N ratio had an overrepresentation of genes for carbon degradation, carbon fixation, metal reductase, and organic remediation categories, while fields with high C : N ratio had an overrepresentation of genes encoding dissimilatory sulfate reductase, methane oxidation, nitrification, and nitrogen fixation. The most abundant genes related to carbon degradation comprised bacterial and fungal cellulases; bacterial and fungal chitinases; fungal laccases; and bacterial, fungal, and oomycete polygalacturonases. The high number of genes related to organic remediation was probably driven by high phosphate content, while the high number of genes for nitrification was probably explained by high total nitrogen content. The functional gene diversity found in different soils did not group the sites accordingly to land management. Rather, the soil factors, C : N ratio, phosphate, and total N, were the main factors driving the differences in functional genes across the fields examined.

  5. Active thermography and post-processing image enhancement for recovering of abraded and paint-covered alphanumeric identification marks

    DEFF Research Database (Denmark)

    Montanini, R.; Quattrocchi, A.; Piccolo, Sebastiano

    2016-01-01

    Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery of the l......Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery...... by means of different manufacturing processes (laser, dot peen, impact, cold press and scribe). Optical excitation of the target surface has been achieved using pulse (PT), lock-in (LT) and step heating (SHT) thermography. Raw infrared images were analysed with a dedicated image processing software...... originally developed in Matlab™, exploiting several methods, which include thermographic signal reconstruction (TSR), guided filtering (GF), block guided filtering (BGF) and logarithmic transformation (LN). Proper image processing of the raw infrared images resulted in superior contrast and enhanced...

  6. Radioactive marking of proteins in cultured mouse embryos

    International Nuclear Information System (INIS)

    Nowak, J.

    1984-01-01

    The purpose of this work was to build an in vitro test system, with which on the one hand postimplantation embryos of the mouse could be cultured without morphological of physiological damage and on the other hand their protein could be as highly marked as possible. With this radioactively marked proteins were to be won, which are optimally suited for a high separation by two-dimensional electrophoresis. In addition incubation and preparation methods were found for the ages of day 10, 11 and 12 of the embryonic development. With the use of 3 H-marked amino acids in the culture medium it was determined that embryos without embryonic membranes, so-called N-embryos, built in more radioactivity into their proteins than the embryos with embryonic membranes, the so-called DAO-embryos or the DO-embryos. On the contrary, the embryos with intact blood circulation (DO-embryos) showed an even distribution of radioactive marker in their bodies. Since an even distribution of the marker in the embryo is a necessary prerequisite for a representative presentation of the proteins by 2DE, the DO-preparation was considered the best suited method. In order to increase the amount of radioactivity incorporated into the proteins of the DO-embryos, the concentration of the used isotope or the incubation length could be increased. A combination of both proved to be the best method. A 14 C-marked amino acid mixture of 20 μCi/corresponds to 20 μl instead of the usual 150 μCi 3 H-marked amino acids in a culture medium proved to be equally suitable. Notable changes which would have indicated a damaging affect of the used radioactivity or the in vitro culturing were not observed. The achieved methodical conditions were used for the presentation of the embryo proteins by two-dimensional electrophoresis and fluorography. (orig./MG) [de

  7. Ageing Management in the CENM Triga Mark II Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    El Younoussi, C.; Nacir, B.; El Bakkari, B.; Boulaich, Y. [Centre for Nuclear Studies of Maâmora (CENM), National Centre of Energy Sciences and Nuclear Techniques (CNESTEN), Rabat (Morocco)

    2014-08-15

    Physical ageing is one of the most important factors that may reduce the safety margins calculated in the design of safety system components of a research reactor. In this context, special efforts are necessary for ensuring the safety of research reactors through appropriate ageing management actions. The paper deals with the overall aspects of the ageing management system of the Moroccan TRIGA Mark II research reactor. The management system covers among others, management of structures, critical components inspections, the control command system and nuclear instrumentation verification. The paper presents also how maintenance and periodic testing are organized and managed in the reactor module. Practical examples of ageing management actions of some systems and components during recent years are presented. (author)

  8. Vent clearing analysis of a Mark III pressure suppression containment

    International Nuclear Information System (INIS)

    Quintana, R.

    1979-01-01

    An analysis of the vent clearing transient in a Mark III pressure suppression containment after a hypothetical LOCA is carried out. A two-dimensional numerical model solving the transient fluid dynamic equations is used. The geometry of the pressure suppression pool is represented and the pressure and velocity fields in the pool are obtained from the moment the LOCA occurs until the first vent in the drywell wall clears. The results are compared to those obtained with the one-diemensional model used for containment design, with special interest on two-dimensional effects. Some conclusions concerning the effect of the water discharged into the suppression pool through the vents on submerged structures are obtained. Future improvements to the model are suggested. (orig.)

  9. Ant Queen Egg-Marking Signals: Matching Deceptive Laboratory Simplicity with Natural Complexity

    DEFF Research Database (Denmark)

    van Zweden, Jelle Stijn; Heinze, Jürgen; Boomsma, Jacobus Jan

    2009-01-01

    Background Experiments under controlled laboratory conditions can produce decisive evidence for testing biological hypotheses, provided they are representative of the more complex natural conditions. However, whether this requirement is fulfilled is seldom tested explicitly. Here we provide a lab....../field comparison to investigate the identity of an egg-marking signal of ant queens. Our study was based on ant workers resolving conflict over male production by destroying each other's eggs, but leaving queen eggs unharmed. For this, the workers need a proximate cue to discriminate between the two egg types...... that this compound by itself is not the natural queen egg-marking pheromone. We subsequently investigated the overall differences of entire chemical profiles of eggs, and found that queen-laid eggs in field colonies are more distinct from worker-laid eggs than in lab colonies, have more variation in profiles...

  10. In and out of the cation pumps: P-type ATPase structure revisited

    DEFF Research Database (Denmark)

    Bublitz, Maike; Poulsen, Hanne; Morth, Jens Preben

    2010-01-01

    Active transport across membranes is a crucial requirement for life. P-type ATPases build up electrochemical gradients at the expense of ATP by forming and splitting a covalent phosphoenzyme intermediate, coupled to conformational changes in the transmembrane section where the ions are translocated....... The marked increment during the last three years in the number of crystal structures of P-type ATPases has greatly improved our understanding of the similarities and differences of pumps with different ion specificities, since the structures of the Ca2+-ATPase, the Na+,K+-ATPase and the H+-ATPase can now...

  11. An industry-scale mass marking technique for tracing farmed fish escapees.

    Directory of Open Access Journals (Sweden)

    Fletcher Warren-Myers

    Full Text Available Farmed fish escape and enter the environment with subsequent effects on wild populations. Reducing escapes requires the ability to trace individuals back to the point of escape, so that escape causes can be identified and technical standards improved. Here, we tested if stable isotope otolith fingerprint marks delivered during routine vaccination could be an accurate, feasible and cost effective marking method, suitable for industrial-scale application. We tested seven stable isotopes, (134Ba, (135Ba, (136Ba, (137Ba, (86Sr, (87Sr and (26Mg, on farmed Atlantic salmon reared in freshwater, in experimental conditions designed to reflect commercial practice. Marking was 100% successful with individual Ba isotopes at concentrations as low as 0.001 µg. g-1 fish and for Sr isotopes at 1 µg. g-1 fish. Our results suggest that 63 unique fingerprint marks can be made at low cost using Ba (0.0002 - 0.02 $US per mark and Sr (0.46 - 0.82 $US per mark isotopes. Stable isotope fingerprinting during vaccination is feasible for commercial application if applied at a company level within the world's largest salmon producing nations. Introducing a mass marking scheme would enable tracing of escapees back to point of origin, which could drive greater compliance, better farm design and improved management practices to reduce escapes.

  12. Incidence of stroke and stroke subtypes in Malmö, Sweden, 1990-2000: marked differences between groups defined by birth country.

    Science.gov (United States)

    Khan, Farhad Ali; Zia, Elisabet; Janzon, Lars; Engstrom, Gunnar

    2004-09-01

    The proportion of immigrants has increased in Sweden markedly during the last decades, as in many other Western countries. Incidence of stroke has increased during this period. However, it is primarily unknown whether incidence of stroke and stroke subtypes in Sweden is related to country of birth. Incidence of first-ever stroke was followed during 10 years in a cohort consisting of all 40- to 89-year-old inhabitants in the city of Malmö, Sweden (n=118,134). Immigrants from 12 different countries were compared with native-born Swedes. Adjusted for age, sex, marital status, and socioeconomic indicators, the incidence of stroke (all subtypes) was significantly higher among immigrants from former Yugoslavia (relative risk [RR], 1.31; 95% CI, 1.1 to 1.6) and Hungary (RR, 1.33; CI, 1.02 to 1.7). A significantly increased incidence of intracerebral hemorrhage was observed in immigrants from Peoples Republic of China or Vietnam (RR, 4.2; CI, 1.7 to 10.4) and the former Soviet Union (RR, 2.7; CI, 1.01 to 7.3). Immigrants from Finland had a significantly higher incidence of subarachnoid hemorrhage (RR, 2.8; CI, 1.1 to 6.8). A significantly lower incidence of stroke was observed in the group from Romania (RR, 0.14; CI, 0.04 to 0.6). Immigrants from Denmark, Norway, Germany, Chile, Czechoslovakia, and Poland had approximately the same risk as citizens born in Sweden. In this urban population from Sweden, there are substantial differences in stroke incidence and stroke subtypes between immigrants from different countries. To what extent this could be accounted for by exposure to biological risk factors remains to be explored.

  13. Signature recognition for rift structures of different sediment strata in ordos basin

    International Nuclear Information System (INIS)

    Zhao Xigang

    2006-10-01

    The rift structure weak information of high Bouguer gravity anomaly data among different Sediment strata are extracted By the horizontal gradient Maximum modulus, the wavelet variation, stripped gravity anomaly of basement and interfaces above/under researched layer, image processing method. So the linear rift structures of different Sediment strata are recognized on data images, such as Cretaceous, Jurassic, Triassic, Permian and Carboniferous, Ordovician System. Development rifts of different Sediment strata occur in stereo structure with quasi-uniform spacing, the rift density of above Sediment stratum is more than lower in different Sediment strata, but the north rift density of the same Sediment stratum is less than south's. It is useful to study rift structure and co-explore for oil, gas, coal and uranium resources in Ordos Basin. (authors)

  14. 46 CFR 160.054-6 - Marking.

    Science.gov (United States)

    2010-10-01

    ... “To Close, Press Together Full Length”. The marking may be applied to the container by the silk screen process, using a suitable ink or paint, or may be applied by other means shown to be acceptable. (b...

  15. Mark's story as oral traditional literature: Rethinking the transmission ...

    African Journals Online (AJOL)

    The interpretation of Mark's gospel is inextricably linked to a conception of the gospel's genesis. By basing his argument on an aspect of the 'oral formulaic theory' the author of this paper argues that Mark's gospel can be seen as an example of oral traditional composition. The primary asset of this perspective is that it ...

  16. A Trust-Based Adaptive Probability Marking and Storage Traceback Scheme for WSNs

    Science.gov (United States)

    Liu, Anfeng; Liu, Xiao; Long, Jun

    2016-01-01

    Security is a pivotal issue for wireless sensor networks (WSNs), which are emerging as a promising platform that enables a wide range of military, scientific, industrial and commercial applications. Traceback, a key cyber-forensics technology, can play an important role in tracing and locating a malicious source to guarantee cybersecurity. In this work a trust-based adaptive probability marking and storage (TAPMS) traceback scheme is proposed to enhance security for WSNs. In a TAPMS scheme, the marking probability is adaptively adjusted according to the security requirements of the network and can substantially reduce the number of marking tuples and improve network lifetime. More importantly, a high trust node is selected to store marking tuples, which can avoid the problem of marking information being lost. Experimental results show that the total number of marking tuples can be reduced in a TAPMS scheme, thus improving network lifetime. At the same time, since the marking tuples are stored in high trust nodes, storage reliability can be guaranteed, and the traceback time can be reduced by more than 80%. PMID:27043566

  17. Different Structures of PVA Nano fibrous Membrane for Sound Absorption Application

    International Nuclear Information System (INIS)

    Mohrova, J.; Kalinova, K.

    2012-01-01

    The thin nano fibrous layer has different properties in the field of sound absorption in comparison with porous fibrous material which works on a principle of friction of air particles in contact with walls of pores. In case of the thin nano fibrous layer, which represents a sound absorber here, the energy of sonic waves is absorbed by the principle of membrane resonance. The structure of the membrane can play an important role in the process of converting the sonic energy to a different energy type. The vibration system acts differently depending on the presence of smooth fibers in the structure, amount of partly merged fibers, or structure of polymer foil as extreme. Polyvinyl alcohol (PVA) was used as a polymer because of its good water solubility. It is possible to influence the structure of nano fibrous layer during the production process thanks to this property of polyvinyl alcohol.

  18. Neural correlates of semantic and syntactic processes in the comprehension of case marked pronouns: Evidence from German and Dutch

    Directory of Open Access Journals (Sweden)

    Hammer Anke

    2006-03-01

    Full Text Available Abstract Background It is well known that both semantic and syntactic information play a role in pronoun resolution in sentences. However, it is unclear what the relative contribution of these sources of information is for the establishment of a coreferential relationship between the pronoun and the antecedent in combination with a local structural case constraint on the pronoun (i.e. case assignment of a pronoun under preposition governing. In a prepositional phrase in German and Dutch, it is the preposition that assigns case to the pronoun. Furthermore, in these languages different overtly case-marked pronouns are used to refer to male and female persons. Thus, one can manipulate biological/syntactic gender features separately from case marking features. The major aim of this study was to determine what the influence of gender information in combination with a local structural case constraint is on the processing of a personal pronoun in a sentence. Event-related brain potential (ERP experiments were performed in German and in Dutch. In a word by word sentence reading study in German and Dutch, gender congruency between the antecedent and the pronoun was manipulated and/or case assignment by the preposition was violated while ERPs of young native speakers were recorded. Results The German and the Dutch ERP data showed an enlarged negativity broadly distributed starting approximately 350 ms after onset of the pronoun followed by a late positivity for gender violations. For syntactic incongruencies without gender violations only a positivity was present. The Dutch data showed an earlier onset of the positivity in comparison to German. Conclusion Finding negativities and positivities for conditions with a gender violation indicates that pronoun resolution with gender incongruency between the pronoun and the antecedent suffers from semantic as well as syntactic integration problems. The presence of a positivity for the syntactically incongruent

  19. Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Smart, Oliver S., E-mail: osmart@globalphasing.com; Womack, Thomas O.; Flensburg, Claus; Keller, Peter; Paciorek, Włodek; Sharff, Andrew; Vonrhein, Clemens; Bricogne, Gérard [Global Phasing Ltd, Sheraton House, Castle Park, Cambridge CB3 0AX (United Kingdom)

    2012-04-01

    Local structural similarity restraints (LSSR) provide a novel method for exploiting NCS or structural similarity to an external target structure. Two examples are given where BUSTER re-refinement of PDB entries with LSSR produces marked improvements, enabling further structural features to be modelled. Maximum-likelihood X-ray macromolecular structure refinement in BUSTER has been extended with restraints facilitating the exploitation of structural similarity. The similarity can be between two or more chains within the structure being refined, thus favouring NCS, or to a distinct ‘target’ structure that remains fixed during refinement. The local structural similarity restraints (LSSR) approach considers all distances less than 5.5 Å between pairs of atoms in the chain to be restrained. For each, the difference from the distance between the corresponding atoms in the related chain is found. LSSR applies a restraint penalty on each difference. A functional form that reaches a plateau for large differences is used to avoid the restraints distorting parts of the structure that are not similar. Because LSSR are local, there is no need to separate out domains. Some restraint pruning is still necessary, but this has been automated. LSSR have been available to academic users of BUSTER since 2009 with the easy-to-use -autoncs and @@target target.pdb options. The use of LSSR is illustrated in the re-refinement of PDB entries http://scripts.iucr.org/cgi-bin/cr.cgi?rm, where -target enables the correct ligand-binding structure to be found, and http://scripts.iucr.org/cgi-bin/cr.cgi?rm, where -autoncs contributes to the location of an additional copy of the cyclic peptide ligand.

  20. 3-D flux distribution and criticality calculation of TRIGA Mark-II

    International Nuclear Information System (INIS)

    Can, B.

    1982-01-01

    In this work, the static calculation of the (I.T.U. TRIGA Mark-II) flux distribution has been made. The three dimensional, r-θ-z, representation of the core has been used. In this representation, for different configuration, the flux distribution has been calculated depending on two group theory. The thermal-hydraulics, the poisoning effects have been ignored. The calculations have been made by using the three dimensional and multigroup code CAN. (author)

  1. 3D road marking reconstruction from street-level calibrated stereo pairs

    Science.gov (United States)

    Soheilian, Bahman; Paparoditis, Nicolas; Boldo, Didier

    This paper presents an automatic approach to road marking reconstruction using stereo pairs acquired by a mobile mapping system in a dense urban area. Two types of road markings were studied: zebra crossings (crosswalks) and dashed lines. These two types of road markings consist of strips having known shape and size. These geometric specifications are used to constrain the recognition of strips. In both cases (i.e. zebra crossings and dashed lines), the reconstruction method consists of three main steps. The first step extracts edge points from the left and right images of a stereo pair and computes 3D linked edges using a matching process. The second step comprises a filtering process that uses the known geometric specifications of road marking objects. The goal is to preserve linked edges that can plausibly belong to road markings and to filter others out. The final step uses the remaining linked edges to fit a theoretical model to the data. The method developed has been used for processing a large number of images. Road markings are successfully and precisely reconstructed in dense urban areas under real traffic conditions.

  2. Protecting the turf: The effect of territorial marking on others' creativity.

    Science.gov (United States)

    Brown, Graham; Baer, Markus

    2015-11-01

    Territorial marking allows people to communicate that a territory has been claimed. Across 2 studies, we examine the impact of territorial marking of one's ideas on others' invited creativity when asked to provide feedback. Integrating research on territoriality and self-construal, we examine the effect of control-oriented marking on invited creativity (Study 1), and the extent to which an independent versus interdependent self-construal moderates this effect (Study 2). Results of Study 1 demonstrate that the use of control-oriented marking to communicate a territorial claim over one's ideas inhibits invited creativity, and this effect is mediated by intrinsic motivation. Also consistent with our hypotheses, the results of Study 2 show that self-construal moderates the effect of control-oriented marking on others' intrinsic motivation and creativity. Marking diminishes invited creativity among people with an independent self-construal but serves to enhance the creativity of those with an interdependent self-construal. Consistent with Study 1, intrinsic motivation mediates this moderated effect. Our results highlight the important but heretofore understudied role of territoriality in affecting others' creativity as well as the role of independent versus interdependent self-construal in shaping this effect. (c) 2015 APA, all rights reserved).

  3. 14 CFR 221.200 - Content and explanation of abbreviations, reference marks and symbols.

    Science.gov (United States)

    2010-01-01

    ..., reference marks and symbols. 221.200 Section 221.200 Aeronautics and Space OFFICE OF THE SECRETARY... § 221.200 Content and explanation of abbreviations, reference marks and symbols. (a) Content. The format..., reference marks and symbols. Abbreviations, reference marks and symbols which are used in the tariff shall...

  4. Scattering analysis of periodic structures using finite-difference time-domain

    CERN Document Server

    ElMahgoub, Khaled; Elsherbeni, Atef Z

    2012-01-01

    Periodic structures are of great importance in electromagnetics due to their wide range of applications such as frequency selective surfaces (FSS), electromagnetic band gap (EBG) structures, periodic absorbers, meta-materials, and many others. The aim of this book is to develop efficient computational algorithms to analyze the scattering properties of various electromagnetic periodic structures using the finite-difference time-domain periodic boundary condition (FDTD/PBC) method. A new FDTD/PBC-based algorithm is introduced to analyze general skewed grid periodic structures while another algor

  5. The theological significance of the Isaiah citation in Mark 4:12 ...

    African Journals Online (AJOL)

    The well-known passage Mark 4:1–34 is no stranger to New Testament scientific scrutiny, not to even mention the hotly debated phrases in Mark 4:10–12. To avoid repetition, the aim with this article is to determine the extent of the impact the Isaiah 6:9–10 citation in Mark 4:12 might have had on the interpretation and ...

  6. Marking of verb tense in the English of preschool English-Mandarin bilingual children: evidence from language development profiles within subgroups on the Singapore English Action Picture Test.

    Science.gov (United States)

    Brebner, Chris; McCormack, Paul; Liow, Susan Rickard

    2016-01-01

    The phonological and morphosyntactic structures of English and Mandarin contrast maximally and an increasing number of bilinguals speak these two languages. Speech and language therapists need to understand bilingual development for children speaking these languages in order reliably to assess and provide intervention for this population. To examine the marking of verb tense in the English of two groups of bilingual pre-schoolers learning these languages in a multilingual setting where the main educational language is English. The main research question addressed was: are there differences in the rate and pattern of acquisition of verb-tense marking for English-language 1 children compared with Mandarin-language 1 children? Spoken language samples in English from 481 English-Mandarin bilingual children were elicited using a 10-item action picture test and analysed for each child's use of verb tense markers: present progressive '-ing', regular past tense '-ed', third-person singular '-s', and irregular past tense and irregular past-participle forms. For 4-6 year olds the use of inflectional markers by the different language dominance groups was compared statistically using non-parametric tests. This study provides further evidence that bilingual language development is not the same as monolingual language development. The results show that there are very different rates and patterns of verb-tense marking in English for English-language 1 and Mandarin-language 1 children. Furthermore, they show that bilingual language development in English in Singapore is not the same as monolingual language development in English, and that there are differences in development depending on language dominance. Valid and reliable assessment of bilingual children's language skills needs to consider the characteristics of all languages spoken, obtaining accurate information on language use over time and accurately establishing language dominance is essential in order to make a

  7. Localizing age-related individual differences in a hierarchical structure

    OpenAIRE

    Salthouse, Timothy A.

    2004-01-01

    Data from 33 separate studies were combined to create an aggregate data set consisting of 16 cognitive variables and 6832 different individuals who ranged between 18 and 95 years of age. Analyses were conducted to determine where in a hierarchical structure of cognitive abilities individual differences associated with age, gender, education, and self-reported health could be localized. The results indicated that each type of individual difference characteristic exhibited a d...

  8. A survey of some metallographic etching reagents for restoration of obliterated engraved marks on aluminium-silicon alloy surfaces.

    Science.gov (United States)

    Uli, Norjaidi; Kuppuswamy, R; Amran, Mohd Firdaus Che

    2011-05-20

    A brief survey to assess the sensitivity and efficacy of some common etching reagents for revealing obliterated engraved marks on Al-Si alloy surfaces is presented. Experimental observations have recommended use of alternate swabbing of 10% NaOH and 10% HNO(3) on the obliterated surfaces for obtaining the desired results. The NaOH etchant responsible for bringing back the original marks resulted in the deposition of some dark coating that has masked the recovered marks. The coating had been well removed by dissolving it in HNO(3) containing 10-20% acid. However, the above etching procedure was not effective on aluminium (99% purity) and Al-Zn-Mg-Cu alloy surfaces. Also the two reagents (i) immersion in 10% aq. phosphoric acid and (ii) alternate swabbing of 60% HCl and 40% NaOH suggested earlier for high strength Al-Zn-Mg-Cu alloys [23] were quite ineffective on Al-Si alloys. Thus different aluminium alloys needed different etching treatments for successfully restoring the obliterated marks. Al-Si alloys used in casting find wide applications especially in the manufacture of engine blocks of motor vehicles. Hence, the results presented in this paper are of much relevance in serial number restoration problems involving this alloy. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  9. Full-scale mark II CRT program data report, (5)

    International Nuclear Information System (INIS)

    Kukita, Yutaka; Namatame, Ken; Yamamoto, Nobuo; Takeshita, Isao; Shiba, Masayoshi

    1980-03-01

    The Full-Scale Mark II CRT (Containment Response Test) Program was initiated in 1977 to provide a data base for evaluation of the LOCA hydrodynamic loads for the Mark II pressure suppression system. The test facility is 1/18 in volume and has a wetwell which is a fullscale replica of one 20 0 -sector of that of a reference Mark II. This report documents test data obtained from TEST 2101, which is a medium size (74 mm) water break test performed on April 27, 1979. TEST 2101 was designed to roughly approximate an intermediate break accident in which so-called chugging phenomenon associated with low-flux steam condensation is anticipated to continue for a longer duration than in a large break accident. (author)

  10. Mark I containment, short term program. Safety evaluation report

    International Nuclear Information System (INIS)

    1977-12-01

    Presented is a Safety Evaluation Report (SER) prepared by the Office of Nuclear Reactor Regulation addressing the Short Term Program (STP) reassessment of the containment systems of operating Boiler Water Reactor (BWR) facilities with the Mark I containment system design. The information presented in this SER establishes the basis for the NRC staff's conclusion that licensed Mark I BWR facilities can continue to operate safely, without undue risk to the health and safety of the public, during an interim period of approximately two years while a methodical, comprehensive Long Term Program (LTP) is conducted. This SER also provides one of the basic foundations for the NRC staff review of the Mark I containment systems for facilities not yet licensed for operation

  11. Ceremony marking Einstein Year

    CERN Multimedia

    2005-01-01

    Sunday 13th November at 10:00amat Geneva's St. Peter's Cathedral To mark Einstein Year and the importance of the intercultural dialogue of which it forms a part, a religious service will take place on Sunday 13 November at 10 a.m. in St. Peter's Cathedral, to which CERN members and colleagues are warmly welcomed. Pastor Henry Babel, senior minister at the Cathedral, will speak on the theme: 'God in Einstein's Universe'. Diether Blechschmidt will convey a message on behalf of the scientific community.

  12. Soil-Borne Microbial Functional Structure across Different Land Uses

    Directory of Open Access Journals (Sweden)

    Eiko E. Kuramae

    2014-01-01

    Full Text Available Land use change alters the structure and composition of microbial communities. However, the links between environmental factors and microbial functions are not well understood. Here we interrogated the functional structure of soil microbial communities across different land uses. In a multivariate regression tree analysis of soil physicochemical properties and genes detected by functional microarrays, the main factor that explained the different microbial community functional structures was C : N ratio. C : N ratio showed a significant positive correlation with clay and soil pH. Fields with low C : N ratio had an overrepresentation of genes for carbon degradation, carbon fixation, metal reductase, and organic remediation categories, while fields with high C : N ratio had an overrepresentation of genes encoding dissimilatory sulfate reductase, methane oxidation, nitrification, and nitrogen fixation. The most abundant genes related to carbon degradation comprised bacterial and fungal cellulases; bacterial and fungal chitinases; fungal laccases; and bacterial, fungal, and oomycete polygalacturonases. The high number of genes related to organic remediation was probably driven by high phosphate content, while the high number of genes for nitrification was probably explained by high total nitrogen content. The functional gene diversity found in different soils did not group the sites accordingly to land management. Rather, the soil factors, C : N ratio, phosphate, and total N, were the main factors driving the differences in functional genes across the fields examined.

  13. MARKED PERSONAL NAMES: AN ANTROPONIMIC STUDY OF BALINESE STUDENTS’ NAMES IN DENPASAR

    Directory of Open Access Journals (Sweden)

    Ni Made Iwan Indrawan

    2015-07-01

    Full Text Available The research aims to account for the Marked Balinese Students’ Personal Names. Four research problems are studied, namely (1 the criteria used to distinguish the marked names (NDMBmk and the unmarked ones (NDMTBmk, (2 the functions of the markedness, (3 the factors that influence it, and (4 the ideologies that operate behind it. The markedness of personal names reflect a relation between the arbitrariness in language uses and the extralinguistic factors influencing it. In the context of Balinese, the tradition, legal practices, and the globalisation may affect the arbitrariness. In order to determine NDMBmk, criteria of markedness was constructed. According to the criteria, structurally, NDMBmk consist of at least five elements, as Anak Agung Arim Kasunu Arya Penarungan. Behaviorally, they may consist of names not derived from Balinese and/or Sanskrit, such as Giovani on I Gede Adeyaka Giovani, adopt a foreign spelling system as Chrisna on Ni Putu Chrisna Wulandari, or use no markers of Balinese ethnics or caste as Yunisari Wira Putri. Out of 698 sampled names, NDMBmk are found 54. Besides denoting, the marked elements also function to distinguish personal identities, to shape the existence of the name holder, to connote particular perception, and to reflect the changing era. The factors influencing the markedness are the need to express something new, a wish to acculturate, to raise status or keep a distance socially, and to demonstrate a linguistic expertise, or when seeing from the concept of imagery, the factors are the imagery on something new and on social status or distancing. The ideologies behind the phenomenon are globalist, nationalist, and the casteless-Balinese.

  14. MARKED PERSONAL NAMES: AN ANTROPONIMIC STUDY OF BALINESE STUDENTS’ NAMES IN DENPASAR

    Directory of Open Access Journals (Sweden)

    Ni Made Iwan Indrawan

    2012-07-01

    Full Text Available The research aims to account for the Marked Balinese Students’ Personal Names. Four research problems are studied, namely (1 the criteria used to distinguish the marked names (NDMBmk and the unmarked ones (NDMTBmk, (2 the functions of the markedness, (3 the factors that influence it, and (4 the ideologies that operate behind it. The markedness of personal names reflect a relation between the arbitrariness in language uses and the extralinguistic factors influencing it. In the context of Balinese, the tradition, legal practices, and the globalisation may affect the arbitrariness. In order to determine NDMBmk, criteria of markedness was constructed. According to the criteria, structurally, NDMBmk consist of at least five elements, as Anak Agung Arim Kasunu Arya Penarungan. Behaviorally, they may consist of names not derived from Balinese and/or Sanskrit, such as Giovani on I Gede Adeyaka Giovani, adopt a foreign spelling system as Chrisna on Ni Putu Chrisna Wulandari, or use no markers of Balinese ethnics or caste as Yunisari Wira Putri. Out of 698 sampled names, NDMBmk are found 54. Besides denoting, the marked elements also function to distinguish personal identities, to shape the existence of the name holder, to connote particular perception, and to reflect the changing era. The factors influencing the markedness are the need to express something new, a wish to acculturate, to raise status or keep a distance socially, and to demonstrate a linguistic expertise, or when seeing from the concept of imagery, the factors are the imagery on something new and on social status or distancing. The ideologies behind the phenomenon are globalist, nationalist, and the casteless-Balinese.

  15. The interplay of attention economics and computer-aided detection marks in screening mammography

    Science.gov (United States)

    Schwartz, Tayler M.; Sridharan, Radhika; Wei, Wei; Lukyanchenko, Olga; Geiser, William; Whitman, Gary J.; Haygood, Tamara Miner

    2016-03-01

    Introduction: According to attention economists, overabundant information leads to decreased attention for individual pieces of information. Computer-aided detection (CAD) alerts radiologists to findings potentially associated with breast cancer but is notorious for creating an abundance of false-positive marks. We suspected that increased CAD marks do not lengthen mammogram interpretation time, as radiologists will selectively disregard these marks when present in larger numbers. We explore the relevance of attention economics in mammography by examining how the number of CAD marks affects interpretation time. Methods: We performed a retrospective review of bilateral digital screening mammograms obtained between January 1, 2011 and February 28, 2014, using only weekend interpretations to decrease distractions and the likelihood of trainee participation. We stratified data according to reader and used ANOVA to assess the relationship between number of CAD marks and interpretation time. Results: Ten radiologists, with median experience after residency of 12.5 years (range 6 to 24,) interpreted 1849 mammograms. When accounting for number of images, Breast Imaging Reporting and Data System category, and breast density, increasing numbers of CAD marks was correlated with longer interpretation time only for the three radiologists with the fewest years of experience (median 7 years.) Conclusion: For the 7 most experienced readers, increasing CAD marks did not lengthen interpretation time. We surmise that as CAD marks increase, the attention given to individual marks decreases. Experienced radiologists may rapidly dismiss larger numbers of CAD marks as false-positive, having learned that devoting extra attention to such marks does not improve clinical detection.

  16. Bench mark spectra for high-energy neutron dosimetry

    International Nuclear Information System (INIS)

    Dierckx, R.

    1986-01-01

    To monitor radiation damage experiments, activation detectors are commonly used. The precision of the results obtained by the multiple foil analysis is largely increased by the intercalibration in bench-mark spectra. This technique is already used in dosimetry measurements for fission reactors. To produce neutron spectra similar to fusion reactor and high-energy high-intensity neutron sources (d-Li or spallation), accelerators can be used. Some possible solutions as p-Be and d-D 2 O neutron sources, useful as bench-mark spectra are described. (author)

  17. Differences in Femoral Geometry and Structure Due to Immobilization

    Science.gov (United States)

    Kiratli, Beatrice Jenny; Yamada, M.; Smith, A.; Marcus, R. M.; Arnaud, S.; vanderMeulen, M. C. H.; Hargens, Alan R. (Technical Monitor)

    1996-01-01

    Reduction in bone mass of the lower extremity is well documented in individuals with paralysis resulting from spinal cord injury (SCI). The consequent osteopenia leads to elevated fracture risk with fractures occurring more commonly in the femoral shaft and supracondylar regions than the hip. A model has recently been described to estimate geometry and structure of the femoral midshaft from whole body scans by dual X-ray absorptiometry (DXA). Increases in femoral geometric and structural properties during growth were primarily related to mechanical loading as reflected by body mass. In this study, we investigate the relationship between body mass and femoral geometry and structure in adults with normal habitual mechanical loading patterns and those with severely reduced loading. The subjects were 78 ambulatory men (aged 20-72 yrs) and 113 men with complete paralysis from SCI of more than 4 years duration (aged 21 73 yrs). Subregional analysis was performed on DXA whole body scans to obtain bone mineral content (BMC, g), cortical thickness (cm), crosssectional moment of inertia (CSMI, cm4), and section modulus (cm3) of the femoral midshaft. All measured bone variables were significantly lower in SCI compared with ambulatory subjects: -29% (BMC), -33% (cortical thickness), -23% (CSMI), and -22% (section modulus) while body mass was not significantly different. However, the associations between body mass and bone properties were notably different; r2 values were higher for ambulatory than SCI subjects in regressions of body mass on BMC (0.48 vs 0.20), CSMI (0.59 vs 0.32), and section modulus (0.59 vs 0.31). No association was seen between body mass and cortical thickness for either group. The greatest difference between groups is in the femoral cortex, consistent with reduced bone mass via endosteal expansion. The relatively lesser difference in geometric and structural properties implies that there is less effect on mechanical integrity than would be expected from

  18. Computational analysis of neutronic parameters for TRIGA Mark-II research reactor using evaluated nuclear data libraries

    International Nuclear Information System (INIS)

    Uddin, M.N.; Sarker, M.M.; Khan, M.J.H.; Islam, S.M.A.

    2010-01-01

    The aim of this study is to analyze the neutronic parameters of TRIGA Mark-II research reactor using the chain of NJOY-WIMS-CITATION computer codes based on evaluated nuclear data libraries CENDL-2.2 and JEFF-3.1.1. The nuclear data processing code NJOY99.0 has been employed to generate the 69 group WIMS library for the isotopes of TRIGA core. The cell code WIMSD-5B was used to generate the cross sections in CITATION format and then 3-dimensional diffusion code CITTATION was used to calculate the neutronic parameters of the TRIGA Mark-II research reactor. All the analyses were performed using the 7-group macroscopic cross section library. The CITATION test-runs using different cross section sets based on different models applied in WIMS calculations have shown a strong influence of those models on the final integral parameters. Some of the cells were specially treated with PRIZE options available in WIMSD-5B to take into account the fine structure of the flux gradient in the fuel-reflector interface region. It was observed that two basic parameters, the effective multiplication factor, k eff and the thermal neutron flux, were in good agreement among the calculated results with each other as well as the measured values. The maximum power densities at the hot spot were 1.0446E02 W/cc and 1.0426E02 W/cc for the libraries CENDL-2.2 and JEFF-3.1.1 respectively. The calculated total peaking factors 5.793 and 5.745 were compared to the original SAR value of 5.6325 as well as MCNP result. Consequently, this analysis will be helpful to enhance the neutronic calculations and also be used for the further thermal-hydraulics study of the TRIGA core.

  19. Geologic bench marks by terrestrial photography

    Science.gov (United States)

    Malde, Harold E.

    1973-01-01

    A photograph made with a level camera, if taken at a known height above a permanent mark on the ground, can be later repeated with exactness for measurement of changes in terrain. Such a photograph is one of several means for establishing a geologic bench mark and is especially useful for monitoring the subtle qualities of a landscape that are otherwise hard to map and describe, including the effects of man's use. Moreover, the geometry of such a photograph provides the same angular measurements between objects as can be made with a transit. A measurement of distance on a single photograph, however, requires control points. These can be surveyed at any convenient time, not necessarily when the initial photograph is made. Distances can also be determined by simple stereophotography from a base line of suitable length.

  20. Review of “Marked Identities. Narrating lives between social labels and individual biographies”

    Directory of Open Access Journals (Sweden)

    Laura Ferrarotti

    2016-01-01

    Full Text Available This is a book review of the volume edited by Roberta Piazza and Alessandra Fasulo, and entitled Marked Identities. Narrating Lives Between Social Labels and Individual Biographies, Palgrave Macmillan, London-New York, 2015. The book consists of various interviews with individuals whose lives, mainly because of the group to which they belong, could be viewed as ‘marked’. The difference between the idea of ‘stigma’ and the notion ‘marked identity’ is underlined, together with the idea of ‘diversity’, which today is not necessarily something that one should hide but, quite the opposite, something one can be proud of. One of the main ideas of this text is that identity is not a rigid reality but a process, by which individuals negotiate the version of who they are with others.

  1. A geometric stochastic approach based on marked point processes for road mark detection from high resolution aerial images

    Science.gov (United States)

    Tournaire, O.; Paparoditis, N.

    Road detection has been a topic of great interest in the photogrammetric and remote sensing communities since the end of the 70s. Many approaches dealing with various sensor resolutions, the nature of the scene or the wished accuracy of the extracted objects have been presented. This topic remains challenging today as the need for accurate and up-to-date data is becoming more and more important. Based on this context, we will study in this paper the road network from a particular point of view, focusing on road marks, and in particular dashed lines. Indeed, they are very useful clues, for evidence of a road, but also for tasks of a higher level. For instance, they can be used to enhance quality and to improve road databases. It is also possible to delineate the different circulation lanes, their width and functionality (speed limit, special lanes for buses or bicycles...). In this paper, we propose a new robust and accurate top-down approach for dashed line detection based on stochastic geometry. Our approach is automatic in the sense that no intervention from a human operator is necessary to initialise the algorithm or to track errors during the process. The core of our approach relies on defining geometric, radiometric and relational models for dashed lines objects. The model also has to deal with the interactions between the different objects making up a line, meaning that it introduces external knowledge taken from specifications. Our strategy is based on a stochastic method, and in particular marked point processes. Our goal is to find the objects configuration minimising an energy function made-up of a data attachment term measuring the consistency of the image with respect to the objects and a regularising term managing the relationship between neighbouring objects. To sample the energy function, we use Green algorithm's; coupled with a simulated annealing to find its minimum. Results from aerial images at various resolutions are presented showing that our

  2. Neutron radiography applications in I.T.U. TRIGA Mark-II reactor

    International Nuclear Information System (INIS)

    Tugrul, A. B.

    2002-01-01

    Neutron radiography is an important radiographic technique which is supplied different and advanced information according to the X or gamma ray radiography. However, it has a trouble for supplying the convenient neutron sources. Tangential beam tube of Istanbul Technical University (ITU) TRIGA Mark-II Training and Research Reactor has been arranged for using neutron radiography. The neutron radiography set defined as detailed for the application of the technique. Two different techniques for neutron radiography are defined as namely, transfer method and direct method. For the transfer method dysprosium and indium screens are used in the study. But, dysprosium generally was preferred in many studies in the point of view nuclear safety. Gadolinium was used for direct method. Two techniques are compared and explained the preferring of the transfer technique. Firstly, reference composition is prepared for seeing the differences between neutron and X-ray or gamma radiography. In addition of it, some radiograph samples are given neutron and X-ray radiography which shows the different image characters. Lastly, some examples are given from archaeometric studies. One of them the brass plates of Great Mosque door in Cizre. After the neutron radiography application, organic dye traces are noticed. Other study is on a sword that belong to Urartu period at the first millennium B.C. It is seen that some wooden part on it. Some different artefacts are examined with neutron radiography from the Ikiztepe excavation site, then some animal post parts are recognized on them. One of them is sword and sheath which are corroded together. After the neutron radiography application, it can be noticed that there are a cloth between the sword and its sheath. By using neutron radiography, many interesting and detailed results are observed in ITU TRIGA Mark-II Training and Research Reactor. Some of them shouldn't be recognised by using any other technique

  3. Blocking oxytocin receptors inhibits vaginal marking to male odors in female Syrian hamsters.

    Science.gov (United States)

    Martinez, Luis A; Albers, H Elliott; Petrulis, Aras

    2010-12-02

    In Syrian hamsters (Mesocricetus auratus), precopulatory behaviors such as vaginal scent marking are essential for attracting a suitable mate. Vaginal marking is dependent on forebrain areas implicated in the neural regulation of reproductive behaviors in rodents, including the medial preoptic/anterior hypothalamus (MPOA-AH). Within MPOA-AH, the neuropeptide oxytocin (OT) acts to facilitate copulation (lordosis), as well as ultrasonic vocalizations towards males. It is not known, however, if OT in this area also facilitates vaginal marking. In the present study, a specific oxytocin receptor antagonist (OTA) was injected into MPOA-AH of intact female Syrian hamsters to determine if oxytocin receptor-dependent signaling is critical for the normal expression of vaginal marking elicited by male, female, and clean odors. OTA injections significantly inhibited vaginal marking in response to male odors compared with vehicle injections. There was no effect of OTA on marking in response to either female or clean odors. When injected into the bed nucleus of the stria terminalis (BNST), a nearby region to MPOA-AH, OTA was equally effective in decreasing marking. Finally, the effects of OTA appear to be specific to vaginal marking, as OTA injections in MPOA-AH or BNST did not alter general locomotor activity, flank marking, or social odor investigation. Considered together, these results suggest that OT in MPOA-AH and/or BNST normally facilitates male odor-induced vaginal marking, providing further evidence that OT generally supports prosocial interactions among conspecifics. Copyright © 2010 Elsevier Inc. All rights reserved.

  4. Application of Solid-State NMR to Reveal Structural Differences in Cefazolin Sodium Pentahydrate from Different Manufacturing Processes

    Science.gov (United States)

    Tian, Ye; Wang, Wei D.; Zou, Wen-Bo; Qian, Jian-Qin; Hu, Chang-Qin

    2018-04-01

    The solid form of an active pharmaceutical ingredient is important when developing a new chemical entity. A solid understanding of the crystal structure and morphology that affect the mechanical and physical characteristics of pharmaceutical powders determines the manufacturing process. Solid-state NMR, thermogravimetric analysis, X-ray diffraction, and Fourier-transform infrared spectroscopy were combined with theoretical calculation to investigate different crystal packings of α-cefazolin sodium from three different vendors and conformational polymorphism was identified to exist in the α-cefazolin sodium. Marginal differences observed among CEZ-Na pentahydrate 1, 2, and 3 were speculated as the proportion of conformation 2. Understanding the differences in the polymorphic structure of α-cefazolin sodium may help with making modifications to incorporate new knowledge with a product’s development.

  5. Do clinicians use more question marks?

    NARCIS (Netherlands)

    Zijlmans, Maeike; Otte, Willem M; Van't Klooster, Maryse A; van Diessen, Eric; Leijten, Frans Ss; Sander, Josemir W

    2015-01-01

    OBJECTIVE: To quantify the use of question marks in titles of published studies. DESIGN AND SETTING: Literature review. PARTICIPANTS: All Pubmed publications between 1 January 2013 and 31 December 2013 with an available abstract. Papers were classified as being clinical when the search terms clin*,

  6. The energetics and structure of nickel clusters: Size dependence

    International Nuclear Information System (INIS)

    Cleveland, C.L.; Landman, U.

    1991-01-01

    The energetics of nickel clusters over a broad size range are explored within the context of the many-body potentials obtained via the embedded atom method. Unconstrained local minimum energy configurations are found for single crystal clusters consisting of various truncations of the cube or octahedron, with and without (110) faces, as well as some monotwinnings of these. We also examine multitwinned structures such as icosahedra and various truncations of the decahedron, such as those of Ino and Marks. These clusters range in size from 142 to over 5000 atoms. As in most such previous studies, such as those on Lennard-Jones systems, we find that icosahedral clusters are favored for the smallest cluster sizes and that Marks' decahedra are favored for intermediate sizes (all our atomic systems larger than about 2300 atoms). Of course very large clusters will be single crystal face-centered-cubic (fcc) polyhedra: the onset of optimally stable single-crystal nickel clusters is estimated to occur at 17 000 atoms. We find, via comparisons to results obtained via atomistic calculations, that simple macroscopic expressions using accurate surface, strain, and twinning energies can usefully predict energy differences between different structures even for clusters of much smaller size than expected. These expressions can be used to assess the relative energetic merits of various structural motifs and their dependence on cluster size

  7. Comparison of Cellulose Supramolecular Structures Between Nanocrystals of Different Origins

    Science.gov (United States)

    Umesh P. Agarwal; Richard S. Reiner; Christopher G. Hunt; Jeffery Catchmark; E. Johan Foster; Akira Isogai

    2015-01-01

    In this study, morphologies and supramolecular structures of CNCs from wood-pulp, cotton, bacteria, tunicate, and cladophora were investigated. TEM was used to study the morphological aspects of the nanocrystals whereas Raman spectroscopy provided information on the cellulose molecular structure and its organization within a CNC. Dimensional differences between the...

  8. Combined pump and marking tests for determining protection zones

    Energy Technology Data Exchange (ETDEWEB)

    Hoetzl, H.; Brauns, J.

    1982-02-01

    Under difficult conditions the determination of the protection area II on the basis of Mear pump tests becomes uncertain. The report shows how in such cases the results of supplementary marking tests can establish a more accurate finding. The execution of combined pump and marking tests enables us to check data gained on a theoretical basis and possibly alter these. This method is described in an example, in which certain hydrogeological conditions and rival interests of ground water protection prevail on the one side and utilization of land on the other side. A general tendency exists to take the utmost protective measure in safeguarding ground water, however in cases of collision of interests the boundary of the protective area should be optimized. Supplementary marking tests can be of great significance.

  9. Composition, structure, and properties of iron-rich nontronites of different origins

    Energy Technology Data Exchange (ETDEWEB)

    Palchik, N. A., E-mail: nadezhda@igm.nsc.ru; Grigorieva, T. N.; Moroz, T. N. [Russian Academy of Sciences, Sobolev Institute of Geology and Mineralogy, Siberian Branch (Russian Federation)

    2013-03-15

    The composition, structure, and properties of smectites of different origins have been studied by X-ray diffraction, IR spectroscopy, scanning electron microscopy, and microprobe analysis. The results showed that nontronites of different origins differ in composition, properties, morphology, and IR spectroscopic characteristics. Depending on the degree of structural order and the negative charge of iron-silicate layers in nontronites, the shift of the 001 reflection to smaller angles as a result of impregnation with ethylene glycol (this shift is characteristic of the smectite group) occurs differently. The calculated values of the parameter b (from 9.11 to 9.14A) are valid for the extreme terms of dioctahedral smectite representatives: nontronites.

  10. The Stingless Bee Melipona solani Deposits a Signature Mixture and Methyl Oleate to Mark Valuable Food Sources.

    Science.gov (United States)

    Alavez-Rosas, David; Malo, Edi A; Guzmán, Miguel A; Sánchez-Guillén, Daniel; Villanueva-Gutiérrez, Rogel; Cruz-López, Leopoldo

    2017-10-01

    Stingless bees foraging for food improve recruitment by depositing chemical cues on valuable food sites or pheromone marks on vegetation. Using gas chromatography/mass spectrometry and bioassays, we showed that Melipona solani foragers leave a mixture composed mostly of long chain hydrocarbons from their abdominal cuticle plus methyl oleate from the labial gland as a scent mark on rich food sites. The composition of hydrocarbons was highly variable among individuals and varied in proportions, depending on the body part. A wide ratio of compounds present in different body parts of the bees elicited electroantennogram responses from foragers and these responses were dose dependent. Generally, in bioassays, these bees prefer to visit previously visited feeders and feeders marked with extracts from any body part of conspecifics. The mean number of visits to a feeder was enhanced when synthetic methyl oleate was added. We propose that this could be a case of multi-source odor marking, in which hydrocarbons, found in large abundance, act as a signature mixture with attraction enhanced through deposition of methyl oleate, which may indicate a rich food source.

  11. Regionaalpoliitika ja arhitektuur / Ülar Mark

    Index Scriptorium Estoniae

    Mark, Ülar

    1999-01-01

    Kagu-Eesti Regionaalarengu Programmi raames Eesti Kunstiakadeemia arhitektuurikateedri IV kursuse eriala valikaines 1998/99 tehtud tööst "HyperMobiilne Reaalsus & Kagu Eesti" (juhendajad Ralf Tamm, Ülar Mark). Ühises töös osalesid Tartu Ülikooli geograafiatudengid (juhendaja Rein Ahas). 4 illustratsiooni

  12. Lines of Evidence–Incremental Markings in Molar Enamel of Soay Sheep as Revealed by a Fluorochrome Labeling and Backscattered Electron Imaging Study

    Science.gov (United States)

    Kierdorf, Horst; Kierdorf, Uwe; Frölich, Kai; Witzel, Carsten

    2013-01-01

    We studied the structural characteristics and periodicities of regular incremental markings in sheep enamel using fluorochrome injections for vital labeling of forming enamel and backscattered electron imaging in the scanning electron microscope. Microscopic analysis of mandibular first molars revealed the presence of incremental markings with a daily periodicity (laminations) that indicated successive positions of the forming front of interprismatic enamel. In addition to the laminations, incremental markings with a sub-daily periodicity were discernible both in interprismatic enamel and in enamel prisms. Five sub-daily increments were present between two consecutive laminations. Backscattered electron imaging revealed that each sub-daily growth increment consisted of a broader and more highly mineralized band and a narrower and less mineralized band (line). The sub-daily markings in the prisms of sheep enamel morphologically resembled the (daily) prisms cross striations seen in primate enamel. Incremental markings with a supra-daily periodicity were not observed in sheep enamel. Based on the periodicity of the incremental markings, maximum mean daily apposition rates of 17.0 µm in buccal enamel and of 13.4 µm in lingual enamel were recorded. Enamel extension rates were also high, with maximum means of 180 µm/day and 217 µm/day in upper crown areas of buccal and lingual enamel, respectively. Values in more cervical crown portions were markedly lower. Our results are in accordance with previous findings in other ungulate species. Using the incremental markings present in primate enamel as a reference could result in a misinterpretation of the incremental markings in ungulate enamel. Thus, the sub-daily growth increments in the prisms of ungulate enamel might be mistaken as prism cross striations with a daily periodicity, and the laminations misidentified as striae of Retzius with a supra-daily periodicity. This would lead to a considerable overestimation of

  13. Marking behavior of Andean bears in an Ecuadorian cloud forest

    NARCIS (Netherlands)

    Filipczyková, Eva; Heitkonig, Ignas; Castellanos, Armando; Hantson, Wouter; Steyaert, Sam M.J.G.

    2017-01-01

    Very little is known about marking behavior of the endangered Andean bear (Tremarctos ornatus). Here, we present a first detailed description of Andean bear marking behavior obtained using camera traps. From November 2012 to April 2013, we inspected 16 bear trails in the Napo province of eastern

  14. 50 CFR 648.84 - Gear-marking requirements and gear restrictions.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Gear-marking requirements and gear... Management Measures for the NE Multispecies and Monkfish Fisheries § 648.84 Gear-marking requirements and gear restrictions. (a) Bottom-tending fixed gear, including, but not limited to, gillnets and longlines...

  15. 7 CFR 906.340 - Container, pack, and container marking regulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container, pack, and container marking regulations... AGRICULTURE ORANGES AND GRAPEFRUIT GROWN IN LOWER RIO GRANDE VALLEY IN TEXAS Container and Pack Requirements § 906.340 Container, pack, and container marking regulations. (a) No handler shall handle any variety of...

  16. Unlike twins: an NMR comparison of two α-synuclein polymorphs featuring different toxicity.

    Directory of Open Access Journals (Sweden)

    Julia Gath

    Full Text Available We structurally compare, using solid-state NMR, two different polymorphs of α-synuclein which, as established recently, display contrasting biochemical properties, toxicity, and tropism for cells. We show that both forms, which can each be produced as a pure polymorph, are greatly different in secondary structure. While β-sheets are the dominating secondary structure elements for both polymorphs, they are markedly divergent in terms of number of elements, as well as their distribution. We demonstrate that all identified β-sheets feature an in-register parallel stacking for both polymorphs. The two forms show a different molecular arrangement in the unit cell and distinct dynamic features, while sharing a highly flexible C-terminal domain. The use of reproducible, well-identified conditions for sample preparation and the recording of identical NMR experiments allows for a direct comparison of the results.

  17. 9 CFR 381.204 - Marking of poultry products offered for entry; official import inspection marks and devices.

    Science.gov (United States)

    2010-01-01

    ... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of poultry products offered...

  18. IP Traceback through modified Probabilistic Packet Marking algorithm using Chinese Remainder Theorem

    Directory of Open Access Journals (Sweden)

    Y. Bhavani

    2015-06-01

    Full Text Available Probabilistic Packet Marking algorithm suggests a methodology to identify all the participated routers of the attack path by probabilistically marking the packets. In this approach, these marked packets contain partial information regarding the routers of the attack path. At receiver, to get the complete information of every router, it requires more number of marked packets and hence more combinations and more false positives. To overcome this drawback we have presented a novel idea in finding the exact IP address of the routers in the attack path by applying Chinese Remainder Theorem. The result of our implementation reveals that our idea requires less number of marked packets and takes no time in constructing the attack path. The same idea is true even in the case of multiple attackers.

  19. Stable isotope tracer marking of individual boll weevils

    International Nuclear Information System (INIS)

    James, W.D.; Showler, A.T.; Armstrong, J.S.; Westbrook, J.K.

    2006-01-01

    Stable isotope markers have been used to study animal nutrition for several decades and more recently to study the foraging and cultural habits of imported fire ants. In this work, we have extended that effort to evaluate the potential for marking boll weevils, Anthonomus grandis grandis Boheman (Coleoptera: Curculionidae), with the rare earth element samarium to aid in studies of insect invasion and pest eradication protocols. Neutron activation analysis (NAA) was performed on the marked boll weevils as well as plant material from the cotton squares on which the insects were fed. Samarium levels in non-dosed insects average about 20 ng/g or about 100 pg total element per insect. Our computed average determination limit was 36 pg samarium/weevil. The determination limit for cotton plant squares and leaves averaged 3.5 ng/g and 8.2 ng/g, respectively. These initial results indicate the NAA method is capable of identifying individual marked insects which have assimilated 1 ng of samarium, a ten-fold increase in content over average blank values. (author)

  20. 26 CFR 1.1296-1 - Mark to market election for marketable stock.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Mark to market election for marketable stock. 1....1296-1 Mark to market election for marketable stock. (a) Definitions—(1) Eligible RIC. An eligible RIC... included in gross income by the company pursuant to such mark to market election with respect to such stock...

  1. 37 CFR 2.72 - Amendments to description or drawing of the mark.

    Science.gov (United States)

    2010-07-01

    ... drawing of the mark. 2.72 Section 2.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND....72 Amendments to description or drawing of the mark. (a) In an application based on use in commerce under section 1(a) of the Act, the applicant may amend the description or drawing of the mark only if...

  2. Fifty tours are being planned to mark CERN's 50th anniversary

    CERN Multimedia

    2004-01-01

    On 16 October 2004, CERN will open its doors to the public. The Visits Service is already busy with preparations for this day of special events to mark the fiftieth anniversary and is recruiting volunteers. A date for your diaries! On 16 October 2004, CERN will be holding an Open Day to mark its golden jubilee. The public will be invited to discover 50 years of history through tours of 50 different sites. Over thirty sites for the tours have already been identified, including the experiment halls, the assembly halls for the LHC detectors and magnets as well as the computer centre and the fire station. With a programme offering tours, talks, a play on a scientific theme and a variety of workshops, there will be something for everybody. A number of evening tours will be organised specifically for the inhabitants of Cessy, St Genis, Meyrin and Ferney Voltaire, where the experiment halls for CMS, ALICE, ATLAS and LHCb are respectively located. An area will even be set aside with stimulating games to enterta...

  3. Influence of different rotor magnetic circuit structure on the performance of permanent magnet synchronous motor

    Directory of Open Access Journals (Sweden)

    Qiu Hongbo

    2017-09-01

    Full Text Available In order to compare the performance difference of the permanent magnet synchronous motors (PMSM with different rotor structure, two kinds of rotor magnetic circuit structure with surface-mounted radial excitation and tangential excitation are designed respectively. By comparing and analyzing the results, the difference of the motor performance was determined. Firstly, based on the finite element method (FEM, the motor electromagnetic field performance was studied, and the magnetic field distribution of the different magnetic circuit structure was obtained. The influence mechanism of the different magnetic circuit structure on the air gap flux density was obtained by using the Fourier theory. Secondly, the cogging torque, output torque and overload capacity of the PMSM with different rotor structure were studied. The effect mechanism of the different rotor structure on the motor output property difference was obtained. The motor prototype with two kinds of rotor structure was manufactured, and the experimental study was carried out. By comparing the experimental data and simulation data, the correctness of the research is verified. This paper lays a foundation for the research on the performance of the PMSM with different magnetic circuit structure.

  4. [Evaluation of the lifetime of nail markings during polio vaccinations in Chad].

    Science.gov (United States)

    Quoc Cuong, Huong; Schlumberger, Martin; Garba Tchang, Salomon; Ould Cheikh, Dah; Savès, Marianne; Mallah, Barah; Demtilo Attilo, Jacques; Ngangro Mosurel, Ndeikoundam; Gamatié, Youssouf

    2010-01-01

    SID (Supplemental Immunization Days) is a special strategy intended to accelerate eradication of poliomyelitis in countries where it is still endemic (India, Afghanistan, and Pakistan in Asia, and Nigeria in Africa). This strategy is also applied in Nigeria's neighbours (Cameroon, Chad, Niger and Benin). Since the poliomyelitis virus was imported from Nigeria in 2001, Chad has reported cases of poliomyelitis every year. After 30 SIDs in Chad and the inaccurate or false attribution of side-effects to polio vaccines, some groups persistently refuse polio vaccination. To ascertain the true coverage of SID, the Ministry of Health and several partners (WHO, UNICEF and Rotary) conduct external coverage evaluations, to identify the under-vaccinated areas where population may be refusing immunization. The nails of the children receiving vaccinations are marked with indelible ink and those markings are the best indicator of the area's actual SID coverage. When coverage investigators arrive and propose vaccination to all children not immunized during SID, mothers who wish to refuse vaccination may claim that the children's markings disappeared after a few days, due to bathing. WHO experts have found that markings applied to their own nails with the WHO-recommended markers persist a few weeks, but others suggested that the markings may disappear much faster among children living in a traditional tropical environment. Until now, the lifetime of these markings has not been tested among children in Africa. To determine the lifetime of the fingernail markings after SID and factors that influence this lifetime in children young than 5 years old in Chad. This prospective cohort study of 200 children (aged 0 to 59 months) took place from March to May 2009 in Milezi, a health zone north of Ndjamena, the capital of Chad, in central Africa. These children received nail markings on their left little finger with an indelible marker pen provided by WHO. The finger was monitored for 35

  5. 15 CFR 1150.3 - Approved markings.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Approved markings. 1150.3 Section 1150.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... permanently affixed to the exterior surface of the barrel, covering the circumference of the barrel from the...

  6. Implementing New Methods of Laser Marking of Items in the Nuclear Material Control and Accountability System at SSC RF-IPPE: An Automated Laser Marking System

    International Nuclear Information System (INIS)

    Regoushevsky, V.I.; Tambovtsev, S.D.; Dvukhsherstnov, V.G.; Efimenko, V.F.; Ilyantsev, A.I.; Russ, G.P. III

    2009-01-01

    For over ten years SSC RF-IPPE, together with the US DOE National Laboratories, has been working on implementing automated control and accountability methods for nuclear materials and other items. Initial efforts to use adhesive bar codes or ones printed (painted) onto metal revealed that these methods were inconvenient and lacked durability under operational conditions. For NM disk applications in critical stands, there is the additional requirement that labels not affect the neutron characteristics of the critical assembly. This is particularly true for the many stainless-steel clad disks containing highly enriched uranium (HEU) and plutonium that are used at SSC RF-IPPE for modeling nuclear power reactors. In search of an alternate method for labeling these disks, we tested several technological options, including laser marking and two-dimensional codes. As a result, the method of laser coloring was chosen in combination with Data Matrix ECC200 symbology. To implement laser marking procedures for the HEU disks and meet all the nuclear material (NM) handling standards and rules, IPPE staff, with U.S. technical and financial support, implemented an automated laser marking system; there are also specially developed procedures for NM movements during laser marking. For the laser marking station, a Zenith 10F system by Telesis Technologies (10 watt Ytterbium Fiber Laser and Merlin software) is used. The presentation includes a flowchart for the automated system and a list of specially developed procedures with comments. Among other things, approaches are discussed for human-factor considerations. To date, markings have been applied to numerous steel-clad HEU disks, and the work continues. In the future this method is expected to be applied to other MC and A items.

  7. Can market structure explain cross-country differences in health?

    Directory of Open Access Journals (Sweden)

    Kate Rybczynski

    2013-03-01

    Full Text Available There is a well documented health disparity between several European countries and the United States. This health gap remains even after controlling for socioeconomic status and risk factors. At the same time, we note that the U.S. market structure is characterized by significantly more large corporations and "super-sized" retail outlets than Europe. Because big business is hierarchical in nature and has been reported to engender urban sprawl, inferior work environments, and loss of social capital, all identified as correlates of poor health, we suggest that differences in market structure may help account for some of the unexplained differences in health across Europe and North America. Using national level data, this study explores the relationship between market structure and health. We investigate whether individuals who live in countries with proportionately more small business are healthier than those who do not. We use two measures of national health: life expectancy at birth, and age-standardized estimates of diabetes rates. Results from ordinary least squares regressions suggest that, there is a large and statistically significant association between market structure (the ratio of small to total businesses and health, even after controlling income, public percent of health expenditure, and obesity rates. This association is robust to additional controls such as insufficient physical activity, smoking, alcohol disease, and air pollution.

  8. Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis

    Science.gov (United States)

    Broseus, Julien; Florensa, Lourdes; Zipperer, Esther; Schnittger, Susanne; Malcovati, Luca; Richebourg, Steven; Lippert, Eric; Cermak, Jaroslav; Evans, Jyoti; Mounier, Morgane; Raya, José Maria; Bailly, François; Gattermann, Norbert; Haferlach, Torsten; Garand, Richard; Allou, Kaoutar; Besses, Carlos; Germing, Ulrich; Haferlach, Claudia; Travaglino, Erica; Luno, Elisa; Pinan, Maria Angeles; Arenillas, Leonor; Rozman, Maria; Perez Sirvent, Maria Luz; Favre, Bernardine; Guy, Julien; Alonso, Esther; Ahwij, Nuhri; Jerez, Andrés; Hermouet, Sylvie; Maynadié, Marc; Cazzola, Mario; Girodon, François

    2012-01-01

    Background Refractory anemia with ring sideroblasts associated with marked thrombocytosis was proposed as a provisional entity in the 2001 World Health Organization classification of myeloid neoplasms and also in the 2008 version, but its existence as a single entity is contested. We wish to define the clinical features of this rare myelodysplastic/myeloproliferative neoplasm and to compare its clinical outcome with that of refractory anemia with ring sideroblasts and essential thrombocythemia. Design and Methods We conducted a collaborative retrospective study across Europe. Our database included 200 patients diagnosed with refractory anemia with ring sideroblasts and marked thrombocytosis. For each of these patients, each patient diagnosed with refractory anemia with ring sideroblasts was matched for age and sex. At the same time, a cohort of 454 patients with essential thrombocythemia was used to compare outcomes of the two diseases. Results In patients with refractory anemia with ring sideroblasts and marked thrombocytosis, depending on the Janus Kinase 2 V617F mutational status (positive or negative) or platelet threshold (over or below 600×109/L), no difference in survival was noted. However, these patients had shorter overall survival and leukemia-free survival with a lower risk of thrombotic complications than did patients with essential thrombocythemia (P<0.001) but better survival (P<0.001) and a higher risk of thrombosis (P=0.039) than patients with refractory anemia with ring sideroblasts. Conclusions The clinical course of refractory anemia with ring sideroblasts and marked thrombocytosis is better than that of refractory anemia with ring sideroblasts and worse than that of essential thrombocythemia. The higher risk of thrombotic events in this disorder suggests that anti-platelet therapy might be considered in this subset of patients. From a clinical point of view, it appears to be important to consider refractory anemia with ring sideroblasts and

  9. Skype'i kaasasutajad investeerivad MarkIT-isse

    Index Scriptorium Estoniae

    2007-01-01

    Nelja eestlasest Skype'i kaasasutaja loodud Ambient Sound Investments (ASI) investeerib 2 miljonit eurot, et aidata kaasa MarkIT e-hankekeskkonna arendamisele ning ettevõtte laienemisele viide Kesk- ja Ida-Euroopa riiki

  10. Trade Mark Coexistence Agreements: What is all the (lack of) fuss about?

    DEFF Research Database (Denmark)

    Elsmore, Matthew J.

    2008-01-01

    time and space is allocated to trade mark coexistence agreements. Despite a shortage of authoritative rulings, it is not immediately clear why, especially as they may be having a profound impact on the use of product markers. Coexistence agreements commonly exist between parties with at least similar...... trade marks who decide to formally coexist, often in the wake of legal skirmishes. In the busy European market, where Community-wide protection is available, an up-front contract may be an attractive way to avoid trade mark conflict. When these contracts work, trade mark law is effectively pre...

  11. Virtual screening applications: a study of ligand-based methods and different structure representations in four different scenarios.

    Science.gov (United States)

    Hristozov, Dimitar P; Oprea, Tudor I; Gasteiger, Johann

    2007-01-01

    Four different ligand-based virtual screening scenarios are studied: (1) prioritizing compounds for subsequent high-throughput screening (HTS); (2) selecting a predefined (small) number of potentially active compounds from a large chemical database; (3) assessing the probability that a given structure will exhibit a given activity; (4) selecting the most active structure(s) for a biological assay. Each of the four scenarios is exemplified by performing retrospective ligand-based virtual screening for eight different biological targets using two large databases--MDDR and WOMBAT. A comparison between the chemical spaces covered by these two databases is presented. The performance of two techniques for ligand--based virtual screening--similarity search with subsequent data fusion (SSDF) and novelty detection with Self-Organizing Maps (ndSOM) is investigated. Three different structure representations--2,048-dimensional Daylight fingerprints, topological autocorrelation weighted by atomic physicochemical properties (sigma electronegativity, polarizability, partial charge, and identity) and radial distribution functions weighted by the same atomic physicochemical properties--are compared. Both methods were found applicable in scenario one. The similarity search was found to perform slightly better in scenario two while the SOM novelty detection is preferred in scenario three. No method/descriptor combination achieved significant success in scenario four.

  12. An evaluation of the accuracy of semi-permanent skin marks for breast cancer irradiation

    International Nuclear Information System (INIS)

    Probst, H.; Dodwell, D.; Gray, J.C.; Holmes, M.

    2006-01-01

    A randomised trial was designed to investigate the accuracy of semi-permanent ink marks versus permanent tattoos for early stage breast cancer irradiation. No significant difference in random and systematic errors was identified between the two groups. On multivariate analysis no specific patient characteristic had a major influence on the systematic errors identified

  13. An evaluation of the accuracy of semi-permanent skin marks for breast cancer irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Probst, H. [Faculty of Health and Wellbeing, Sheffield Hallam University, Collegiate Crescent Campus, Sheffield S10 2BP (United Kingdom)]. E-mail: h.probst@shu.ac.uk; Dodwell, D. [Cookridge Hospital Leeds (United Kingdom); Gray, J.C. [University of Newcastle (United Kingdom); Holmes, M. [Leeds Metropolitan University (United Kingdom)

    2006-08-15

    A randomised trial was designed to investigate the accuracy of semi-permanent ink marks versus permanent tattoos for early stage breast cancer irradiation. No significant difference in random and systematic errors was identified between the two groups. On multivariate analysis no specific patient characteristic had a major influence on the systematic errors identified.

  14. EcoMark: Evaluating Models of Vehicular Environmental Impact

    DEFF Research Database (Denmark)

    Guo, Chenjuan; Ma, Mike; Yang, Bin

    2012-01-01

    The reduction of greenhouse gas (GHG) emissions from transporta- tion is essential for achieving politically agreed upon emissions re- duction targets that aim to combat global climate change. So-called eco-routing and eco-driving are able to substantially reduce GHG emissions caused by vehicular...... the vehicle travels in. We develop an evaluation framework, called EcoMark, for such environmental impact models. In addition, we survey all eleven state-of-the-art impact models known to us. To gain insight into the capabilities of the models and to understand the effectiveness of the EcoMark, we apply...

  15. Using Marking Criteria to Improve Learning: An Evaluation of Student Perceptions

    Directory of Open Access Journals (Sweden)

    Swapna Koshy

    2009-02-01

    Full Text Available This paper is an exploratory study on the use of Marking Criteria in the offshore campus of an Australian University in the Middle East. The purpose of the study is to analyse student attitudes to the use of Marking Criteria with a view to maximizing its use. Most educators agree that assessment plays a key role in education and the use of Marking Criteria helps to streamline assessment. The study notes that most students were aware of the benefits of reviewing criteria before they worked on an assessment but few actually used it. The paper offers ways to help students internalise criteria to make learning effective. It also proposes the use of Marking Criteria as a tool that aids teachers in giving feedback in large classes.

  16. Estimating abundance without recaptures of marked pallid sturgeon in the Mississippi River.

    Science.gov (United States)

    Friedenberg, Nicholas A; Hoover, Jan Jeffrey; Boysen, Krista; Killgore, K Jack

    2018-04-01

    Abundance estimates are essential for assessing the viability of populations and the risks posed by alternative management actions. An effort to estimate abundance via a repeated mark-recapture experiment may fail to recapture marked individuals. We devised a method for obtaining lower bounds on abundance in the absence of recaptures for both panmictic and spatially structured populations. The method assumes few enough recaptures were expected to be missed by random chance. The upper Bayesian credible limit on expected recaptures allows probabilistic statements about the minimum number of individuals present in the population. We applied this method to data from a 12-year survey of pallid sturgeon (Scaphirhynchus albus) in the lower and middle Mississippi River (U.S.A.). None of the 241 individuals marked was recaptured in the survey. After accounting for survival and movement, our model-averaged estimate of the total abundance of pallid sturgeon ≥3 years old in the study area had a 1%, 5%, or 25% chance of being <4,600, 7,000, or 15,000, respectively. When we assumed fish were distributed in proportion to survey catch per unit effort, the farthest downstream reach in the survey hosted at least 4.5-15 fish per river kilometer (rkm), whereas the remainder of the reaches in the lower and middle Mississippi River hosted at least 2.6-8.5 fish/rkm for all model variations examined. The lower Mississippi River had an average density of pallid sturgeon ≥3 years old of at least 3.0-9.8 fish/rkm. The choice of Bayesian prior was the largest source of uncertainty we considered but did not alter the order of magnitude of lower bounds. Nil-recapture estimates of abundance are highly uncertain and require careful communication but can deliver insights from experiments that might otherwise be considered a failure. © 2017 Society for Conservation Biology.

  17. 49 CFR 172.301 - General marking requirements for non-bulk packagings.

    Science.gov (United States)

    2010-10-01

    ... Liquefied petroleum gas (LPG) unless it is legibly marked NON-ODORIZED or NOT ODORIZED in letters not less... empty packagings, see § 173.29 of this subchapter.) (f) NON-ODORIZED marking on cylinders containing LPG...

  18. Trichomes: different regulatory networks lead to convergent structures.

    Science.gov (United States)

    Serna, Laura; Martin, Cathie

    2006-06-01

    Sometimes, proteins, biological structures or even organisms have similar functions and appearances but have evolved through widely divergent pathways. There is experimental evidence to suggest that different developmental pathways have converged to produce similar outgrowths of the aerial plant epidermis, referred to as trichomes. The emerging picture suggests that trichomes in Arabidopsis thaliana and, perhaps, in cotton develop through a transcriptional regulatory network that differs from those regulating trichome formation in Antirrhinum and Solanaceous species. Several lines of evidence suggest that the duplication of a gene controlling anthocyanin production and subsequent divergence might be the major force driving trichome formation in Arabidopsis, whereas the multicellular trichomes of Antirrhinum and Solanaceous species appear to have a different regulatory origin.

  19. Monopoly, Pareto and Ramsey mark-ups

    NARCIS (Netherlands)

    Ten Raa, T.

    2009-01-01

    Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear

  20. 27 CFR 28.216 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.216 Section 28.216 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Exportation of Wine With Benefit of Drawback § 28.216...

  1. Magnetic properties of dendrimer structures with different coordination numbers: A Monte Carlo study

    International Nuclear Information System (INIS)

    Masrour, R.; Jabar, A.

    2016-01-01

    We investigate the magnetic properties of Cayley trees of large molecules with dendrimer structure using Monte Carlo simulations. The thermal magnetization and magnetic susceptibility of a dendrimer structure are given with different coordination numbers, Z=3, 4, 5 and different generations g=3 and 2. The variation of magnetizations with the exchange interactions and crystal fields have been given of this system. The magnetic hysteresis cycles have been established. - Highlights: • The dendrimer structure is investigated using Monte Carlo simulations. • The transition temperatures are obtained for different coordination numbers and generations. • The magnetic hysteresis cycle has been established. • The dendrimer structure exhibit the superparamagnetic behavior.

  2. Magnetic properties of dendrimer structures with different coordination numbers: A Monte Carlo study

    Energy Technology Data Exchange (ETDEWEB)

    Masrour, R., E-mail: rachidmasrour@hotmail.com; Jabar, A.

    2016-11-01

    We investigate the magnetic properties of Cayley trees of large molecules with dendrimer structure using Monte Carlo simulations. The thermal magnetization and magnetic susceptibility of a dendrimer structure are given with different coordination numbers, Z=3, 4, 5 and different generations g=3 and 2. The variation of magnetizations with the exchange interactions and crystal fields have been given of this system. The magnetic hysteresis cycles have been established. - Highlights: • The dendrimer structure is investigated using Monte Carlo simulations. • The transition temperatures are obtained for different coordination numbers and generations. • The magnetic hysteresis cycle has been established. • The dendrimer structure exhibit the superparamagnetic behavior.

  3. Isotopic marking and tracers

    International Nuclear Information System (INIS)

    Morel, F.

    1997-01-01

    The use of radioactive isotopes as tracers in biology has been developed thanks to the economic generation of the required isotopes in accelerators and nuclear reactors, and to the multiple applications of tracers in the life domain; the most usual isotopes employed in biology are carbon, hydrogen, phosphorus and sulfur isotopes, because these elements are present in most of organic molecules. Most of the life science knowledge appears to be dependent to the extensive use of nuclear tools and radioactive tracers; the example of the utilization of radioactive phosphorus marked ATP to study the multiple reactions with proteins, nucleic acids, etc., is given

  4. Trade reforms, mark-ups and bargaining power of workers: the case ...

    African Journals Online (AJOL)

    Ethiopian Journal of Economics ... workers between 1996 and 2007, a model of mark-up with labor bargaining power was estimated using random effects and LDPDM. ... Keywords: Trade reform, mark-up, bargaining power, rent, trade unions ...

  5. Different design approaches to structural fire safety

    DEFF Research Database (Denmark)

    Giuliani, Luisa; Budny, I.

    2013-01-01

    -priori evaluate which design is the safest or the most economical one: a punctual analysis of the different aspects and a comparison of the resulting designs is therefore of interest and is presented in this paper with reference to the case study considered.The third approach refers instead to a performance......-based fire design of the structure(PBFD), where safety goals are explicitly defined and a deeper knowledge of the structural response to fire effects can be achieved, for example with the avail of finite element analyses (FEA). On the other hand, designers can’t follow established procedures when undertaking...... such advanced investigations, which are generally quite complex ones, due to the presence of material degradation and large displacements induced by fire, as well as the possible triggering of local mechanism in the system. An example of advanced investigations for fire design is given in the paper...

  6. Mark II containment lead plant program load evaluation and acceptance criteria

    International Nuclear Information System (INIS)

    1978-10-01

    The report, prepared by the Office of Nuclear Reactor Regulation, addresses the portion of the Mark II owner's program that provides a generic methodology for establishing design basis LOCA and safety relief valve loads for the lead Mark II facilities (Zimmer, Shoreham, and LaSalle), i.e., the lead plant program. The report includes an evaluation of the Mark II owner's load methodology, a description of load methodologies that we find acceptable for use in the individual plant unique assessments, and the basis for the stated conclusions

  7. Marking pike fry otoliths with alizarin complexone and strontium : an evaluation of methods

    DEFF Research Database (Denmark)

    Skov, Christian; Grønkjær, P.; Nielsen, C.

    2001-01-01

    Laboratory experiments demonstrated that both alizarin complexone and strontium are useful in mass marking of pike Esox lucius fry otoliths. Visual detection of alizarin complexone marks was considered more reliable than the quantitative analysis of strontium for differentiating marked and unmarked...

  8. Automated road marking recognition system

    Science.gov (United States)

    Ziyatdinov, R. R.; Shigabiev, R. R.; Talipov, D. N.

    2017-09-01

    Development of the automated road marking recognition systems in existing and future vehicles control systems is an urgent task. One way to implement such systems is the use of neural networks. To test the possibility of using neural network software has been developed with the use of a single-layer perceptron. The resulting system based on neural network has successfully coped with the task both when driving in the daytime and at night.

  9. Different zooplankton structures in the German Bight

    Science.gov (United States)

    Martens, P.; Brockmann, U.

    1993-06-01

    In August 1982, a net of 48 stations with altogether 208 samples was investigated in the eastern German Bight with respect to temperature, salinity, as well as the amount and species composition of the mesozooplankton (>80 μm). The data were arranged into different structures by means of a cluster analysis. Four different clusters were found: (a) a “Wadden sea water” with few holoplankton organisms but a higher amount of spionid larvae; (b) a “German Bight water” with a maximum occurrence of turbellaria ( Alaurina composita) and medium concentrations of copepods; (c) a mixing area between these two water masses with highest amounts of Oikopleura dioica, Temora longicornis, Acartia sp., mussel larvae and larvae of the spionid worms; (d) a “North Sea water” mass with highest concentrations of Pseudocalanus elongatus, Paracalanus parvus und Oithona similis. The differences in the concentrations of the species mentioned between the four clusters were significant on the 0.1%-level.

  10. Nest marking behavior and chemical composition of olfactory cues involved in nest recognition in Megachile rotundata.

    Science.gov (United States)

    Guédot, Christelle; Buckner, James S; Hagen, Marcia M; Bosch, Jordi; Kemp, William P; Pitts-Singer, Theresa L

    2013-08-01

    In-nest observations of the solitary bee, Megachile rotundata (F.), revealed that nesting females apply olfactory cues to nests for nest recognition. On their way in and out of the nest, females drag the abdomen along the entire length of the nest, and sometimes deposit fluid droplets from the tip of the abdomen. The removal of bee-marked sections of the nest resulted in hesitation and searching behavior by females, indicating the loss of olfactory cues used for nest recognition. Chemical analysis of female cuticles and the deposits inside marked nesting tubes revealed the presence of hydrocarbons, wax esters, fatty aldehydes, and fatty alcohol acetate esters. Chemical compositions were similar across tube samples, but proportionally different from cuticular extracts. These findings reveal the importance of lipids as chemical signals for nest recognition and suggest that the nest-marking cues are derived from a source in addition to, or other than, the female cuticle.

  11. First results from Mark III at SPEAR

    International Nuclear Information System (INIS)

    Einsweiler, K.F.

    The paper presents data on meson decays obtained using the MARK III detector operating at SPEAR. Results on hadronic decays; decays of the etasub(e); and results on radiative decays; are all described. (U.K.)

  12. The Four Marks of Holistic Kinesiology

    Science.gov (United States)

    Twietmeyer, Gregg

    2012-01-01

    What, to borrow a theological phrase, are the marks of a truly holistic kinesiology department? "In Kinesis and the Nature of the Human Person" (2010), I examined the theoretical impact of Aristotle's definition of "kinesis" and Polanyi's theory of "tacit knowledge" on kinesiology. The intention here, however, is practical rather than theoretical.…

  13. MARK TWAIN IN THE RUSSIAN PERIODICALS. Part 1

    Directory of Open Access Journals (Sweden)

    Ekaterina A. Stetsenko

    2017-06-01

    Full Text Available This article deals with the interpretation of the works by Mark Twain, famous Ame- This article deals with the interpretation of the works by Mark Twain, famous American author, in the Russian pre-revolutionary periodical press (1872–1916. The objects of research are critical articles, essays, reviews, correspondences, introductions to publica tions of Twain’s short stories and novels, obituaries, and other materials printed in central and provincial magazines and newspapers. Perception of Twain in Russia was contingent on many factors including political and cultural situation in the country, state of social thought and literary criticism, newspaper and magazine conjuncture etc., always remain ing polysemantic and conflicting. In different times, in the years of democratic rising or reaction critics looked for something in Twain’s works that corresponded to the spirit of their time and helped solve ideological and aesthetic problems. Twain had reputation of either a “pure humorist” or a great writer, philosopher, and moralist. Democrats, liberals, conservatives, feminists, adepts of realistic or naturalistic trends in art discussed Twain’s works that became a source of knowledge about the United States and inspired polemics about Russia’s further development. Twain was highly esteemed as the author of books for children and young people. Yet his works that criticized monarchism and imperialism were often ignored or abridged. The history of Twain’s interpretation in the Russian press serves as evidence of the fact that perception of foreign literature is a dynamic and bumpy pro cess, repeating itself and moving backwards but also getting to deeper levels of meanings.

  14. Definition of distance for nonlinear time series analysis of marked point process data

    Energy Technology Data Exchange (ETDEWEB)

    Iwayama, Koji, E-mail: koji@sat.t.u-tokyo.ac.jp [Research Institute for Food and Agriculture, Ryukoku Univeristy, 1-5 Yokotani, Seta Oe-cho, Otsu-Shi, Shiga 520-2194 (Japan); Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

    2017-01-30

    Marked point process data are time series of discrete events accompanied with some values, such as economic trades, earthquakes, and lightnings. A distance for marked point process data allows us to apply nonlinear time series analysis to such data. We propose a distance for marked point process data which can be calculated much faster than the existing distance when the number of marks is small. Furthermore, under some assumptions, the Kullback–Leibler divergences between posterior distributions for neighbors defined by this distance are small. We performed some numerical simulations showing that analysis based on the proposed distance is effective. - Highlights: • A new distance for marked point process data is proposed. • The distance can be computed fast enough for a small number of marks. • The method to optimize parameter values of the distance is also proposed. • Numerical simulations indicate that the analysis based on the distance is effective.

  15. The Mark, the Thing, and the Object: On What Commands Repetition in Freud and Lacan.

    Science.gov (United States)

    Van de Vijver, Gertrudis; Bazan, Ariane; Detandt, Sandrine

    2017-01-01

    In Logique du Fantasme , Lacan argues that the compulsion to repeat does not obey the same discharge logic as homeostatic processes. Repetition installs a realm that is categorically different from the one related to homeostatic pleasure seeking, a properly subjective one, one in which the mark "stands for," "takes the place of," what we have ventured to call "an event," and what only in the movement of return, in what Lacan calls a "thinking of repetition," confirms and ever reconfirms this point of no return, which is also a qualitative cut and a structural loss. The kind of "standing for" Lacan intends here with the concept of repetition is certainly not something like an image or a faithful description. No, what Lacan wishes to stress is that this mark is situated at another level, at another place, it is " entstellt ," and as such, it is punctually impinging upon the bodily dynamics without rendering the event, without having an external meta-point of view, but cutting across registers according to a logics that is not the homeostatic memory logics. This paper elaborates on this distinction on the basis of a confrontation with what Freud says about the pleasure principle and its beyond in Beyond the Pleasure Principle , and also takes inspiration from Freud's Project for a Scientific Psychology. We argue that Lacan's theory of enjoyment takes up and generalizes what Freud was after in Beyond the Pleasure Principle with the Wiederholungszwang , and pushes Freud's thoughts to a more articulated point: to the point where a subject is considered to speak only when it has allowed the other, through discourse, to have impacted and cut into his bodily pleasure dynamics.

  16. Full-scale mark II CRT program data report, No. 9

    International Nuclear Information System (INIS)

    Takeshita, Isao; Yamamoto, Nobuo; Kukita, Yutaka; Namatame, Ken; Shiba, Masayoshi

    1980-07-01

    Recorded data for TEST 1202 conducted on the Full-Scale Mark II CRT (Containment Responce Test) Facility are presented. The TEST 1202 is a test under the condition of steam discharge with a large break diameter (240 mm) and the second one of the steam discharge pool swell test series. It is also one of the parametric tests with different break diameters, i.e. TEST 1201 (200 mm), TEST 1202 (240 mm) and TEST 1203 (220 mm). The test was successful and a value of 225 kPa/s was obtained as the initial pressurization rate in the drywell. (author)

  17. Structural coloration of metallic surfaces with micro/nano-structures induced by elliptical vibration texturing

    Science.gov (United States)

    Yang, Yang; Pan, Yayue; Guo, Ping

    2017-04-01

    Creating orderly periodic micro/nano-structures on metallic surfaces, or structural coloration, for control of surface apparent color and optical reflectivity has been an exciting research topic over the years. The direct applications of structural coloration include color marking, display devices, and invisibility cloak. This paper presents an efficient method to colorize metallic surfaces with periodic micro/nano-gratings using elliptical vibration texturing. When the tool vibration is coupled with a constant cutting velocity, controlled periodic ripples can be generated due to the overlapping tool trajectory. These periodic ripples with a wavelength near visible spectrum can act as micro-gratings to introduce iridescent colors. The proposed technique also provides a flexible method for color marking of metallic surfaces with arbitrary patterns and images by precise control of the spacing distance and orientation of induced micro/nano-ripples. Theoretical analysis and experimental results are given to demonstrate structural coloration of metals by a direct mechanical machining technique.

  18. Balancing medicine prices and business sustainability: analyses of pharmacy costs, revenues and profit shed light on retail medicine mark-ups in rural Kyrgyzstan.

    Science.gov (United States)

    Waning, Brenda; Maddix, Jason; Soucy, Lyne

    2010-07-13

    Numerous not-for-profit pharmacies have been created to improve access to medicines for the poor, but many have failed due to insufficient financial planning and management. These pharmacies are not well described in health services literature despite strong demand from policy makers, implementers, and researchers. Surveys reporting unaffordable medicine prices and high mark-ups have spurred efforts to reduce medicine prices, but price reduction goals are arbitrary in the absence of information on pharmacy costs, revenues, and profit structures. Health services research is needed to develop sustainable and "reasonable" medicine price goals and strategic initiatives to reach them. We utilized cost accounting methods on inventory and financial information obtained from a not-for-profit rural pharmacy network in mountainous Kyrgyzstan to quantify costs, revenues, profits and medicine mark-ups during establishment and maintenance periods (October 2004-December 2007). Twelve pharmacies and one warehouse were established in remote Kyrgyzstan with 100%, respectively. Annual mark-ups increased dramatically each year to cover increasing recurrent costs, and by 2007, only 19% and 46% of products revealed mark-ups of 100%. 2007 medicine mark-ups varied substantially across these products, ranging from 32% to 244%. Mark-ups needed to sustain private pharmacies would be even higher in the absence of government subsidies. Pharmacy networks can be established in hard-to-reach regions with little funding using public-private partnership, resource-sharing models. Medicine prices and mark-ups must be interpreted with consideration for regional costs of business. Mark-ups vary dramatically across medicines. Some mark-ups appear "excessive" but are likely necessary for pharmacy viability. Pharmacy financial data is available in remote settings and can be used towards determination of "reasonable" medicine price goals. Health systems researchers must document the positive and negative

  19. User's guide : pavement marking management system database.

    Science.gov (United States)

    2011-12-01

    Pavement markings play a critical role in maintaining a safe and efficient driving environment for road users, especially during nighttime conditions. The Texas Department of Transportation (TxDOT) spends millions of dollars each year for installatio...

  20. Diverse and participative learning methodologies: a remedial teaching intervention for low marks dental students in Chile.

    Science.gov (United States)

    Alcota, Marcela; Muñoz, Andrea; González, Fermín E

    2011-10-01

    The purpose of this educational intervention was to diagnose the learning style of a group of low marks (i.e., grades) dental students in Chile and improve their academic achievement by means of remedial teaching. The intervention group was composed of ten students in endodontics and eleven in pedodontics with low marks. These two groups were mutually exclusive. The Kolb test of learning styles was applied to the low mark students group and to the rest of the class (n=72). Diverse methodologies were applied to the low marks students, such as seminars, case-based learning and problem-based learning, directed study, plenary discussions and debate, integration and questions, and web-based learning in an effort to cover all learning styles. Students' perceptions of the educational intervention were assessed by means of a questionnaire. The learning styles of the low marks group were mainly divergent (52.4 percent) and convergent (19 percent). Accommodators and assimilators were 14.3 percent each. The rest of the class showed a very distinct frequencies distribution: divergent 18 percent, convergent 20 percent, accommodators 28 percent, and assimilators 34 percent. After the educational intervention, the mean of the scores obtained by the intervention group in formal evaluations was higher than the average scores obtained before the intervention for both courses. Students' perceptions of the activities were that they were effective for their learning process (76 percent) and that the teaching methodologies were useful mainly to clarify concepts and contents from both courses (82 percent). We can conclude that the use of diverse and participative teaching methodologies in a remedial teaching intervention, to cover all the different learning styles of the students, contributes to improve their marks in formal evaluations.

  1. Entropy of level-cut random Gaussian structures at different volume fractions.

    Science.gov (United States)

    Marčelja, Stjepan

    2017-10-01

    Cutting random Gaussian fields at a given level can create a variety of morphologically different two- or several-phase structures that have often been used to describe physical systems. The entropy of such structures depends on the covariance function of the generating Gaussian random field, which in turn depends on its spectral density. But the entropy of level-cut structures also depends on the volume fractions of different phases, which is determined by the selection of the cutting level. This dependence has been neglected in earlier work. We evaluate the entropy of several lattice models to show that, even in the cases of strongly coupled systems, the dependence of the entropy of level-cut structures on molar fractions of the constituents scales with the simple ideal noninteracting system formula. In the last section, we discuss the application of the results to binary or ternary fluids and microemulsions.

  2. Entropy of level-cut random Gaussian structures at different volume fractions

    Science.gov (United States)

    Marčelja, Stjepan

    2017-10-01

    Cutting random Gaussian fields at a given level can create a variety of morphologically different two- or several-phase structures that have often been used to describe physical systems. The entropy of such structures depends on the covariance function of the generating Gaussian random field, which in turn depends on its spectral density. But the entropy of level-cut structures also depends on the volume fractions of different phases, which is determined by the selection of the cutting level. This dependence has been neglected in earlier work. We evaluate the entropy of several lattice models to show that, even in the cases of strongly coupled systems, the dependence of the entropy of level-cut structures on molar fractions of the constituents scales with the simple ideal noninteracting system formula. In the last section, we discuss the application of the results to binary or ternary fluids and microemulsions.

  3. Restoration of abraded and covered marks engraved in steel using active infrared thermography

    DEFF Research Database (Denmark)

    Quattrocchi, A.; Piccolo, Sebastiano; Montanini, R.

    2016-01-01

    Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery of the l......Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery...

  4. Teaching Mark through a postcolonial optic

    African Journals Online (AJOL)

    2015-07-16

    Jul 16, 2015 ... question, eliciting answers that range from Mark as in direct and open ... or armed response, especially in a context where such actions were unrealistic. (whether ..... identity; social memory; to name a few) of power. It implies ... an elite-driven enterprise in the simplistic sense of the word, although the elite's ...

  5. 49 CFR 15.13 - Marking SSI.

    Science.gov (United States)

    2010-10-01

    ... SSI. (a) Marking of paper records. In the case of paper records containing SSI, a covered person must... limitation statement on the bottom, of— (1) The outside of any front and back cover, including a binder cover... types of records. In the case of non-paper records that contain SSI, including motion picture films...

  6. Primary Science Quality Mark--2016 Update

    Science.gov (United States)

    Turner, Jane

    2016-01-01

    Back in May 2011, an article in "Primary Science" described how the idea for a quality mark for primary science was developed from an initial conversation at an Association for Science Education annual conference (Turner, Marshall and Elsmore, 2011). Its intention then, as now, was to support and champion good practice and raise the…

  7. Meet EPA Chemist Mark Strynar, Ph.D.

    Science.gov (United States)

    Dr. Mark Strynar is a physical scientist in EPA's Office of Research and Development. His research interests include developing methods to measure and analyze the movement of PFCs and other xenobiotic compounds in biological and environmental media

  8. Technical specifications manual for the MARK-1 pulsed ionizing radiation detection system

    International Nuclear Information System (INIS)

    Lawrence, R.S.; Harker, Y.D.; Jones, J.L.; Hoggan, J.M.

    1993-03-01

    The MARK-1 detection system was developed by the Idaho National Engineering Laboratory for the US Department of Energy Office of Arms Control and Nonproliferation. The completely portable system was designed for the detection and analysis of intense photon emissions from pulsed ionizing radiation sources. This manual presents the technical design specifications for the MARK-1 detection system and was written primarily to assist the support or service technician in the service, calibration, and repair of the system. The manual presents the general detection system theory, the MARK-1 component design specifications, the acquisition and control software, the data processing sequence, and the system calibration procedure. A second manual entitled: Volume 2: Operations Manual for the MARK-1 Pulsed Ionizing Radiation Detection System (USDOE Report WINCO-1108, September 1992) provides a general operational description of the MARK-1 detection system. The Operations Manual was written primarily to assist the field operator in system operations and analysis of the data

  9. Optical diameters of stars measured with the Mt. Wilson Mark III interferometer

    International Nuclear Information System (INIS)

    Simon, R.S.; Mozurkewich, D.; Johnston, K.J.; Gaume, R.; Hutter, D.J.; Bowers, P.F.; Colavita, M.M.; Shao, M.

    1990-01-01

    Reliable stellar angular diameters can now be determined using the Mark III Optical Interferometer located on Mt. Wilson, California. The Mark III is a Michelson Interferometer capable of measuring the interferometric fringe visibility for stars using interferometer baselines varying from 3 to 31.5 meters in length. Angular diameters measured with the Mark III Optical Interferometer are presented for 12 stars at wavelengths of 450 and 800 nm. 10 refs

  10. ASSESSING THE SO CALLED MARKED INFLECTIONAL FEATURES OF NIGERIAN ENGLISH: A SECOND LANGUAGE ACQUISITION THEORY ACCOUNT

    OpenAIRE

    Boluwaji Oshodi

    2014-01-01

    There are conflicting claims among scholars on whether the structural outputs of the types of English spoken in countries where English is used as a second language gives such speech forms the status of varieties of English. This study examined those morphological features considered to be marked features of the variety spoken in Nigeria according to Kirkpatrick (2011) and the variety spoken in Malaysia by considering the claims of the Missing Surface Inflection Hypothesis (MSIH) a Second Lan...

  11. Structural and optical studies of nano-structure silica gel doped with different rare earth elements, prepared by two different sol -gel techniques

    International Nuclear Information System (INIS)

    Battisha, I.K.; El Beyally, A.; Seliman, S.I.; El Nahrawi, A.S.

    2005-01-01

    Structural and optical characteristics of pure silica gel (silica-xerogel, SiO 2 ) and doped with different concentrations ranging from 1 up to 6% of some rare earth (REEs) ions such as, praseodymium Pr +3 ,and Europium Eu +3 , Erbium Er +3 and Holmium Ho +3 , ions, in the form of thin film and monolith materials were prepared by sol - gel technique, Using tetra-ethoxysilane as precursor materials, which are of particular interest for sol-gel integrated optics applications. Some structural and optical features of sol-gel derived monolith and thin films are analyzed and compared, namely the structure of nano-particle monolith and thin film silica-gel samples, based on X-ray diffraction (XRD). The types of structural information obtainable are compared in detail. It is show that the XRD spectra of a-cristobalite are obtained for the two type materials and even by doping with the four REEs ions. Optical measurements of monolith and thin films were also studied and compared, the normal transmission and specular reflection were measured. The refractive index were calculated and discussed

  12. Structural differences between yeast and mammalian microtubules revealed by cryo-EM

    Energy Technology Data Exchange (ETDEWEB)

    Howes, Stuart C. [Univ. of California, Berkeley, CA (United States). Biophysics Graduate Group; Geyer, Elisabeth A. [Univ. of Texas Southwestern Medical Center, Dallas, TX (United States). Dept. of Biophysics; Univ. of Texas Southwestern Medical Center, Dallas, TX (United States). Dept. of Biochemistry; LaFrance, Benjamin [Univ. of California, Berkeley, CA (United States). Molecular and Cell Biology Graduate Program; Zhang, Rui [Univ. of California, Berkeley, CA (United States). Howard Hughes Medical Inst.; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Molecular Biophysics and Integrated Bioimaging Division; Kellogg, Elizabeth H. [Univ. of California, Berkeley, CA (United States). Howard Hughes Medical Inst.; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Molecular Biophysics and Integrated Bioimaging Division; Westermann, Stefan [Univ. of Duisburg-Essen, Essen (Germany). Dept. of Molecular Genetics, Center for Medical Biotechnology; Rice, Luke M. [Univ. of Texas Southwestern Medical Center, Dallas, TX (United States). Dept. of Biophysics; Univ. of Texas Southwestern Medical Center, Dallas, TX (United States). Dept. of Biochemistry; Nogales, Eva [Univ. of California, Berkeley, CA (United States). Howard Hughes Medical Inst.; Univ. of California, Berkeley, CA (United States). Dept. of Molecular Biology and California Inst. for Quantitative Biosciences; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Molecular Biophysics and Integrated Bioimaging Division

    2017-06-26

    Microtubules are polymers of αβ-tubulin heterodimers essential for all eukaryotes. Despite sequence conservation, there are significant structural differences between microtubules assembled in vitro from mammalian or budding yeast tubulin. Yeast MTs were not observed to undergo compaction at the interdimer interface as seen for mammalian microtubules upon GTP hydrolysis. Lack of compaction might reflect slower GTP hydrolysis or a different degree of allosteric coupling in the lattice. The microtubule plus end–tracking protein Bim1 binds yeast microtubules both between αβ-tubulin heterodimers, as seen for other organisms, and within tubulin dimers, but binds mammalian tubulin only at interdimer contacts. At the concentrations used in cryo-electron microscopy, Bim1 causes the compaction of yeast microtubules and induces their rapid disassembly. In conclusion, our studies demonstrate structural differences between yeast and mammalian microtubules that likely underlie their differing polymerization dynamics. These differences may reflect adaptations to the demands of different cell size or range of physiological growth temperatures.

  13. Track structure in radiation biology: theory and applications.

    Science.gov (United States)

    Nikjoo, H; Uehara, S; Wilson, W E; Hoshi, M; Goodhead, D T

    1998-04-01

    A brief review is presented of the basic concepts in track structure and the relative merit of various theoretical approaches adopted in Monte-Carlo track-structure codes are examined. In the second part of the paper, a formal cluster analysis is introduced to calculate cluster-distance distributions. Total experimental ionization cross-sections were least-square fitted and compared with the calculation by various theoretical methods. Monte-Carlo track-structure code Kurbuc was used to examine and compare the spectrum of the secondary electrons generated by using functions given by Born-Bethe, Jain-Khare, Gryzinsky, Kim-Rudd, Mott and Vriens' theories. The cluster analysis in track structure was carried out using the k-means method and Hartigan algorithm. Data are presented on experimental and calculated total ionization cross-sections: inverse mean free path (IMFP) as a function of electron energy used in Monte-Carlo track-structure codes; the spectrum of secondary electrons generated by different functions for 500 eV primary electrons; cluster analysis for 4 MeV and 20 MeV alpha-particles in terms of the frequency of total cluster energy to the root-mean-square (rms) radius of the cluster and differential distance distributions for a pair of clusters; and finally relative frequency distribution for energy deposited in DNA, single-strand break and double-strand breaks for 10MeV/u protons, alpha-particles and carbon ions. There are a number of Monte-Carlo track-structure codes that have been developed independently and the bench-marking presented in this paper allows a better choice of the theoretical method adopted in a track-structure code to be made. A systematic bench-marking of cross-sections and spectra of the secondary electrons shows differences between the codes at atomic level, but such differences are not significant in biophysical modelling at the macromolecular level. Clustered-damage evaluation shows: that a substantial proportion of dose ( 30%) is

  14. Evolving knowledge of sex differences in brain structure, function, and chemistry.

    Science.gov (United States)

    Cosgrove, Kelly P; Mazure, Carolyn M; Staley, Julie K

    2007-10-15

    Clinical and epidemiologic evidence demonstrates sex differences in the prevalence and course of various psychiatric disorders. Understanding sex-specific brain differences in healthy individuals is a critical first step toward understanding sex-specific expression of psychiatric disorders. Here, we evaluate evidence on sex differences in brain structure, chemistry, and function using imaging methodologies, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single photon emission computed tomography (SPECT), and structural magnetic resonance imaging (MRI) in mentally healthy individuals. MEDLINE searches of English-language literature (1980-November 2006) using the terms sex, gender, PET, SPECT, MRI, fMRI, morphometry, neurochemistry, and neurotransmission were performed to extract relevant sources. The literature suggests that while there are many similarities in brain structure, function, and neurotransmission in healthy men and women, there are important differences that distinguish the male from the female brain. Overall, brain volume is greater in men than women; yet, when controlling for total volume, women have a higher percentage of gray matter and men a higher percentage of white matter. Regional volume differences are less consistent. Global cerebral blood flow is higher in women than in men. Sex-specific differences in dopaminergic, serotonergic, and gamma-aminobutyric acid (GABA)ergic markers indicate that male and female brains are neurochemically distinct. Insight into the etiology of sex differences in the normal living human brain provides an important foundation to delineate the pathophysiological mechanisms underlying sex differences in neuropsychiatric disorders and to guide the development of sex-specific treatments for these devastating brain disorders.

  15. Modelled seasonal influenza mortality shows marked differences in risk by age, sex, ethnicity and socioeconomic position in New Zealand.

    Science.gov (United States)

    Khieu, Trang Q T; Pierse, Nevil; Telfar-Barnard, Lucy Frances; Zhang, Jane; Huang, Q Sue; Baker, Michael G

    2017-09-01

    Influenza is responsible for a large number of deaths which can only be estimated using modelling methods. Such methods have rarely been applied to describe the major socio-demographic characteristics of this disease burden. We used quasi Poisson regression models with weekly counts of deaths and isolates of influenza A, B and respiratory syncytial virus for the period 1994 to 2008. The estimated average mortality rate was 13.5 per 100,000 people which was 1.8% of all deaths in New Zealand. Influenza mortality differed markedly by age, sex, ethnicity and socioeconomic position. Relatively vulnerable groups were males aged 65-79 years (Rate ratio (RR) = 1.9, 95% CI: 1.9, 1.9 compared with females), Māori (RR = 3.6, 95% CI: 3.6, 3.7 compared with European/Others aged 65-79 years), Pacific (RR = 2.4, 95% CI: 2.4, 2.4 compared with European/Others aged 65-79 years) and those living in the most deprived areas (RR = 1.8, 95% CI: 1.3, 2.4) for New Zealand Deprivation (NZDep) 9&10 (the most deprived) compared with NZDep 1&2 (the least deprived). These results support targeting influenza vaccination and other interventions to the most vulnerable groups, in particular Māori and Pacific people and men aged 65-79 years and those living in the most deprived areas. Copyright © 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  16. Interview with Professor Mark Wilcox.

    Science.gov (United States)

    Wilcox, Mark

    2016-08-01

    Mark Wilcox speaks to Georgia Patey, Commissioning Editor: Professor Mark Wilcox is a Consultant Microbiologist and Head of Microbiology at the Leeds Teaching Hospitals (Leeds, UK), the Professor of Medical Microbiology at the University of Leeds (Leeds, UK), and is the Lead on Clostridium difficile and the Head of the UK C. difficile Reference Laboratory for Public Health England (PHE). He was the Director of Infection Prevention (4 years), Infection Control Doctor (8 years) and Clinical Director of Pathology (6 years) at the Leeds Teaching Hospitals. He is Chair of PHE's Rapid Review Panel (reviews utility of infection prevention and control products for National Health Service), Deputy Chair of the UK Department of Health's Antimicrobial Resistance and Healthcare Associated Infection Committee and a member of PHE's HCAI/AR Programme Board. He is a member of UK/European/US working groups on C. difficile infection. He has provided clinical advice as part of the FDA/EMA submissions for the approval of multiple novel antimicrobial agents. He heads a healthcare-associated infection research team at University of Leeds, comprising approximately 30 doctors, scientists and nurses; projects include multiple aspects of C. difficile infection, diagnostics, antimicrobial resistance and the clinical development of new antimicrobial agents. He has authored more than 400 publications, and is the coeditor of Antimicrobial Chemotherapy (5th/6th/7th Editions, 15 December 2007).

  17. Nekroloog turundusele / Mark Earls ; interv. Margo Kokerov

    Index Scriptorium Estoniae

    Earls, Mark

    2003-01-01

    Turunduskommunikatsioonifirma Ogilvy & Mather suunajuht Mark Earls leiab, et kuna turg on üle ujutatud võrdselt heade toodetega ja tarbija teab, et tegelikult pole oluline, millise toote ta valib, muutub turundusrevolutsiooni keskne idee - tarbijavajaduste kindlakstegemine ja rahuldamine - tähtsusetuks.

  18. 49 CFR 192.63 - Marking of materials.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.63 Marking of materials. (a) Except as...

  19. 27 CFR 20.178 - Marks and brands on containers of specially denatured spirits.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marks and brands on... Dealers § 20.178 Marks and brands on containers of specially denatured spirits. (a) Required marks. Each... officer, or (2) Consist of a brand name, or consist of caution notices, or consist of other material...

  20. Assessment of statistical agreement of three techniques for the study of cut marks: 3D digital microscope, laser scanning confocal microscopy and micro-photogrammetry.

    Science.gov (United States)

    Maté-González, Miguel Ángel; Aramendi, Julia; Yravedra, José; Blasco, Ruth; Rosell, Jordi; González-Aguilera, Diego; Domínguez-Rodrigo, Manuel

    2017-09-01

    In the last few years, the study of cut marks on bone surfaces has become fundamental for the interpretation of prehistoric butchery practices. Due to the difficulties in the correct identification of cut marks, many criteria for their description and classification have been suggested. Different techniques, such as three-dimensional digital microscope (3D DM), laser scanning confocal microscopy (LSCM) and micro-photogrammetry (M-PG) have been recently applied to the study of cut marks. Although the 3D DM and LSCM microscopic techniques are the most commonly used for the 3D identification of cut marks, M-PG has also proved to be very efficient and a low-cost method. M-PG is a noninvasive technique that allows the study of the cortical surface without any previous preparation of the samples, and that generates high-resolution models. Despite the current application of microscopic and micro-photogrammetric techniques to taphonomy, their reliability has never been tested. In this paper, we compare 3D DM, LSCM and M-PG in order to assess their resolution and results. In this study, we analyse 26 experimental cut marks generated with a metal knife. The quantitative and qualitative information registered is analysed by means of standard multivariate statistics and geometric morphometrics to assess the similarities and differences obtained with the different methodologies. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

  1. Protein flexibility: coordinate uncertainties and interpretation of structural differences

    Energy Technology Data Exchange (ETDEWEB)

    Rashin, Alexander A., E-mail: alexander-rashin@hotmail.com [BioChemComp Inc., 543 Sagamore Avenue, Teaneck, NJ 07666 (United States); LH Baker Center for Bioinformatics and Department of Biochemistry, Biophysics and Molecular Biology, 112 Office and Lab Building, Iowa State University, Ames, IA 50011-3020 (United States); Rashin, Abraham H. L. [BioChemComp Inc., 543 Sagamore Avenue, Teaneck, NJ 07666 (United States); Rutgers, The State University of New Jersey, 22371 BPO WAY, Piscataway, NJ 08854-8123 (United States); Jernigan, Robert L. [LH Baker Center for Bioinformatics and Department of Biochemistry, Biophysics and Molecular Biology, 112 Office and Lab Building, Iowa State University, Ames, IA 50011-3020 (United States); BioChemComp Inc., 543 Sagamore Avenue, Teaneck, NJ 07666 (United States)

    2009-11-01

    Criteria for the interpretability of coordinate differences and a new method for identifying rigid-body motions and nonrigid deformations in protein conformational changes are developed and applied to functionally induced and crystallization-induced conformational changes. Valid interpretations of conformational movements in protein structures determined by X-ray crystallography require that the movement magnitudes exceed their uncertainty threshold. Here, it is shown that such thresholds can be obtained from the distance difference matrices (DDMs) of 1014 pairs of independently determined structures of bovine ribonuclease A and sperm whale myoglobin, with no explanations provided for reportedly minor coordinate differences. The smallest magnitudes of reportedly functional motions are just above these thresholds. Uncertainty thresholds can provide objective criteria that distinguish between true conformational changes and apparent ‘noise’, showing that some previous interpretations of protein coordinate changes attributed to external conditions or mutations may be doubtful or erroneous. The use of uncertainty thresholds, DDMs, the newly introduced CDDMs (contact distance difference matrices) and a novel simple rotation algorithm allows a more meaningful classification and description of protein motions, distinguishing between various rigid-fragment motions and nonrigid conformational deformations. It is also shown that half of 75 pairs of identical molecules, each from the same asymmetric crystallographic cell, exhibit coordinate differences that range from just outside the coordinate uncertainty threshold to the full magnitude of large functional movements. Thus, crystallization might often induce protein conformational changes that are comparable to those related to or induced by the protein function.

  2. Structural differences of xylans affect their interaction with cellulose

    NARCIS (Netherlands)

    Kabel, M.A.; Borne, van den H.; Vincken, J.P.; Voragen, A.G.J.; Schols, H.A.

    2007-01-01

    The affinity of xylan to cellulose is an important aspect of many industrial processes, e.g. production of cellulose, paper making and bio-ethanol production. However, little is known about the adsorption of structurally different xylans to cellulose. Therefore, the adsorption of various xylans to

  3. German Children's Use of Word Order and Case Marking to Interpret Simple and Complex Sentences: Testing Differences between Constructions and Lexical Items

    Science.gov (United States)

    Brandt, Silke; Lieven, Elena; Tomasello, Michael

    2016-01-01

    Children and adults follow cues such as case marking and word order in their assignment of semantic roles in simple transitives (e.g., "the dog chased the cat"). It has been suggested that the same cues are used for the interpretation of complex sentences, such as transitive relative clauses (RCs) (e.g., "that's the dog that chased…

  4. Design Report for the core design of the first core Mark-Ia of the SNR-300

    International Nuclear Information System (INIS)

    Stanculescu, A.

    1984-05-01

    The report describes the first core Mark-Ia of the SNR-300 reactor and its different assembly types with their operational strategy. Methods, criteria and results of the neutron physical, thermal hydraulic and core mechanical design of the whole core and its assemblies are presented

  5. Do chondroitin sulfates with different structures have different activities on chondrocytes and macrophages?

    Science.gov (United States)

    da Cunha, André L; Aguiar, Jair A K; Correa da Silva, Flavio S; Michelacci, Yara M

    2017-10-01

    The aim of the present study was to investigate the activities of natural chondroitin sulfates (CS) with different structures on cultured chondrocytes and macrophages. CS were isolated from cartilages of bovine trachea (BT), porcine trachea (PT), chicken sternum (Ch) and skate (Sk). The preparations were 90-98% pure, with ∼1% proteins, nucleic acids and keratan sulfate contaminants. Structural analysis of these CS and of commercial chondroitin 4- and 6-sulfate (C4S, C6S) have shown that most of their disaccharides are monosulfated, with varying proportions of 4- and 6-sulfation, and 2-7% non-sulfated disaccharides. Sk-CS and C6S contained detectable amounts of disulfated disaccharides. All the CS were polydisperse, with modal molecular weights of 26-135kDa. These CS had anti-inflammatory activities on both chondrocytes and macrophages, but with different efficiencies. On horse and human chondrocytes, they reduced the IL-1β-induced liberation of NO and PGE 2 , and on RAW 264.7 immortalized macrophage-like cell line, C4S, C6S, Ch and Sk-CS decreased the LPS-induced liberation of TNF-α, but did not affect IL-6. In contrast, on bone marrow derived macrophages, C4S, C6S, BT and PT-CS reduced the LPS-induced liberation of TNF-α, IL-6, IL-1β and NO, indicating that the RAW response to CS was different from that of primary macrophages. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. 75 FR 59102 - Defense Federal Acquisition Regulation Supplement; Government-Assigned Serial Number Marking...

    Science.gov (United States)

    2010-09-27

    ... version of MIL-STD-130, Marking of U.S. Military Property, shall be used for the marking of human-readable... Valuation; and (2) Require the contractor to mark major end items under the terms and conditions of the... revising the introductory text to read as follows: 252.211-7003 Item identification and valuation. As...

  7. Bad faith trade mark applications in China : a threat to foreign investment?

    OpenAIRE

    Elftorp, Kristian

    2012-01-01

    In a report provided by the European Chamber of Commerce in China, the problem with bad faith trade mark applications was highlighted. The report concluded that the current application of the law, combined with the procedural background constitutes an incentive rather than a deterrent for bad faith trade mark applications in China. The issue originates in Chinese defrauders conducting research among foreign companies with the intent of un- lawfully registering their trade marks in China. Sinc...

  8. Automatic Extraction of Road Markings from Mobile Laser-Point Cloud Using Intensity Data

    Science.gov (United States)

    Yao, L.; Chen, Q.; Qin, C.; Wu, H.; Zhang, S.

    2018-04-01

    With the development of intelligent transportation, road's high precision information data has been widely applied in many fields. This paper proposes a concise and practical way to extract road marking information from point cloud data collected by mobile mapping system (MMS). The method contains three steps. Firstly, road surface is segmented through edge detection from scan lines. Then the intensity image is generated by inverse distance weighted (IDW) interpolation and the road marking is extracted by using adaptive threshold segmentation based on integral image without intensity calibration. Moreover, the noise is reduced by removing a small number of plaque pixels from binary image. Finally, point cloud mapped from binary image is clustered into marking objects according to Euclidean distance, and using a series of algorithms including template matching and feature attribute filtering for the classification of linear markings, arrow markings and guidelines. Through processing the point cloud data collected by RIEGL VUX-1 in case area, the results show that the F-score of marking extraction is 0.83, and the average classification rate is 0.9.

  9. Kuosheng Mark III containment analyses using GOTHIC

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Ansheng, E-mail: samuellin1999@iner.gov.tw; Chen, Yen-Shu; Yuann, Yng-Ruey

    2013-10-15

    Highlights: • The Kuosheng Mark III containment model is established using GOTHIC. • Containment pressure and temperature responses due to LOCA are presented. • The calculated results are all below the design values and compared with the FSAR results. • The calculated results can be served as an analysis reference for an SPU project in the future. -- Abstract: Kuosheng nuclear power plant in Taiwan is a twin-unit BWR/6 plant, and both units utilize the Mark III containment. Currently, the plant is performing a stretch power uprate (SPU) project to increase the core thermal power to 103.7% OLTP (original licensed thermal power). However, the containment response in the Kuosheng Final Safety Analysis Report (FSAR) was completed more than twenty-five years ago. The purpose of this study is to establish a Kuosheng Mark III containment model using the containment program GOTHIC. The containment pressure and temperature responses under the design-basis accidents, which are the main steam line break (MSLB) and the recirculation line break (RCLB) accidents, are investigated. Short-term and long-term analyses are presented in this study. The short-term analysis is to calculate the drywell peak pressure and temperature which happen in the early stage of the LOCAs. The long-term analysis is to calculate the peak pressure and temperature of the reactor building space. In the short-term analysis, the calculated peak drywell to wetwell differential pressure is 140.6 kPa for the MSLB, which is below than the design value of 189.6 kPa. The calculated peak drywell temperature is 158 °C, which is still below the design value of 165.6 °C. In addition, in the long-term analysis, the calculated peak containment pressure is 47 kPa G, which is below the design value of 103.4 kPa G. The calculated peak values of containment temperatures are 74.7 °C, which is lower than the design value of 93.3 °C. Therefore, the Kuosheng Mark III containment can maintain the integrity after

  10. Does Grammatical Structure Accelerate Number Word Learning? Evidence from Learners of Dual and Non-Dual Dialects of Slovenian.

    Directory of Open Access Journals (Sweden)

    Franc Marušič

    Full Text Available How does linguistic structure affect children's acquisition of early number word meanings? Previous studies have tested this question by comparing how children learning languages with different grammatical representations of number learn the meanings of labels for small numbers, like 1, 2, and 3. For example, children who acquire a language with singular-plural marking, like English, are faster to learn the word for 1 than children learning a language that lacks the singular-plural distinction, perhaps because the word for 1 is always used in singular contexts, highlighting its meaning. These studies are problematic, however, because reported differences in number word learning may be due to unmeasured cross-cultural differences rather than specific linguistic differences. To address this problem, we investigated number word learning in four groups of children from a single culture who spoke different dialects of the same language that differed chiefly with respect to how they grammatically mark number. We found that learning a dialect which features "dual" morphology (marking of pairs accelerated children's acquisition of the number word two relative to learning a "non-dual" dialect of the same language.

  11. Does Grammatical Structure Accelerate Number Word Learning? Evidence from Learners of Dual and Non-Dual Dialects of Slovenian

    Science.gov (United States)

    Plesničar, Vesna; Razboršek, Tina; Sullivan, Jessica; Barner, David

    2016-01-01

    How does linguistic structure affect children’s acquisition of early number word meanings? Previous studies have tested this question by comparing how children learning languages with different grammatical representations of number learn the meanings of labels for small numbers, like 1, 2, and 3. For example, children who acquire a language with singular-plural marking, like English, are faster to learn the word for 1 than children learning a language that lacks the singular-plural distinction, perhaps because the word for 1 is always used in singular contexts, highlighting its meaning. These studies are problematic, however, because reported differences in number word learning may be due to unmeasured cross-cultural differences rather than specific linguistic differences. To address this problem, we investigated number word learning in four groups of children from a single culture who spoke different dialects of the same language that differed chiefly with respect to how they grammatically mark number. We found that learning a dialect which features “dual” morphology (marking of pairs) accelerated children’s acquisition of the number word two relative to learning a “non-dual” dialect of the same language. PMID:27486802

  12. Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species.

    Science.gov (United States)

    Smith, Kathrine J; Petit, Chantal M; Aubart, Kelly; Smyth, Martin; McManus, Edward; Jones, Jo; Fosberry, Andrew; Lewis, Ceri; Lonetto, Michael; Christensen, Siegfried B

    2003-02-01

    Polypeptide deformylase (PDF) catalyzes the deformylation of polypeptide chains in bacteria. It is essential for bacterial cell viability and is a potential antibacterial drug target. Here, we report the crystal structures of polypeptide deformylase from four different species of bacteria: Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Escherichia coli. Comparison of these four structures reveals significant overall differences between the two Gram-negative species (E. coli and H. influenzae) and the two Gram-positive species (S. pneumoniae and S. aureus). Despite these differences and low overall sequence identity, the S1' pocket of PDF is well conserved among the four enzymes studied. We also describe the binding of nonpeptidic inhibitor molecules SB-485345, SB-543668, and SB-505684 to both S. pneumoniae and E. coli PDF. Comparison of these structures shows similar binding interactions with both Gram-negative and Gram-positive species. Understanding the similarities and subtle differences in active site structure between species will help to design broad-spectrum polypeptide deformylase inhibitor molecules.

  13. ESTIMATING THE STOCK OF GLASS EELS IN AN ESTUARY BY MARK-RECAPTURE EXPERIMENTS USING VITAL DYES

    Directory of Open Access Journals (Sweden)

    BRIAND C.

    2005-10-01

    Full Text Available Glass eels (Anguilla anguilla arriving after the fishing season in the Vilaine estuary (France were caught by boat and at a trapping ladder located at a blocking dam upstream in the estuary. They were marked with Bismarck brown, rhodamine B or neutral red, and released into the estuary. The effect of marking on behaviour, mortality and recapture differed according to the dye and concentration used. The glass eels also differed in response to marking according to their origin. Estuarine glass eels were clearly desynchronized in their selective tidal stream transport and left the release area after a few tidal cycles. Trapped glass eels were less sensitive to marking. They remained in the release area and were recaptured in larger number both in the trapping ladder and in the estuary. These results supported a model of two behavioral fractions in the estuary: flow-carried migrants and active glass eels with stronger rheotactic behaviour. The proportion of active glass eels in the estuary shifted from none for the two weeks after the fishery closure, to 10% value of the total stock. At the trapping ladder, the migration ended in June each year, while a large stock was still present in the estuary. These observations favour the interpretation of a short duration of the active phase at this site followed by the transition towards a more benthic behavior. The daily efficiency of the trapping ladder was calculated as 4% of the active stock from both stock estimations and average recapture rate. This value was consistent with the low annual efficiency of the trapping ladder, calculated as 30% of the estuarine stock of glass eels that arrived after the fishing season.

  14. A Space View of Radar Archaeological Marks: First Applications of COSMO-SkyMed X-Band Data

    Directory of Open Access Journals (Sweden)

    Fulong Chen

    2014-12-01

    Full Text Available With the development of Synthetic Aperture Radar (SAR in terms of multi-band, multi-polarization and high-resolution data, space radar remote sensing for archaeology has become a potential field for research. Nevertheless, the archaeological detection capability of this technology has so far not been fully assessed. This paper is a pioneering effort to assess the potential of satellite SAR X-band data in the detection of archaeological marks. We focus on the results obtained from a collaborative contribution jointly carried out by archaeologists and remote sensing experts in order to test the use of COSMO-SkyMed data in different contexts and environmental conditions. The methodological approaches we adopted are based on two different feature-enhancement procedures: (i multi-temporal analysis performed to reduce noise and highlight archaeological marks; (ii single-date analysis to assess the ability of the single SAR scene to detect archaeological features like with optical remote sensing. Results from multi-temporal data analysis, conducted using 40 scenes from COSMO-SkyMed X-band Stripmap data (27 February to 17 October 2013, enable us to detect unknown archaeological crop, soil, and shadow marks representing Luoyang city, dating from the Eastern-Han to Northern-Wei Dynasties. Single-date analyses were conducted using COSMO-SkyMed Spotlight scenes acquired for Sabratha (Libya and Metapontum (southern Italy. These case studies were selected because they are characterized by diverse superficial conditions (desert and Mediterranean area and archaeological marks (crop, soil and shadow. The results we obtained for both of them show that even a single SAR X-band acquisition is a feasible and effective approach for archaeological prospection. Overall, the methodological approach adopted demonstrated that both multi-temporal and single-date analysis are suitable for the enhancement of archaeological and palaeoenvironmental features.

  15. 38 CFR 3.2130 - Will VA accept a signature by mark or thumbprint?

    Science.gov (United States)

    2010-07-01

    ... signature by mark or thumbprint? 3.2130 Section 3.2130 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... of This Title General § 3.2130 Will VA accept a signature by mark or thumbprint? VA will accept signatures by mark or thumbprint if: (a) They are witnessed by two people who sign their names and give their...

  16. 19 CFR 134.47 - Souvenirs and articles marked with trademarks or trade names.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Souvenirs and articles marked with trademarks or... Imported Articles § 134.47 Souvenirs and articles marked with trademarks or trade names. When as part of a trademark or trade name or as part of a souvenir marking, the name of a location in the United States or...

  17. Design loads, loading combinations and structural acceptance criteria for BWR containments in the United States

    International Nuclear Information System (INIS)

    Edwards, N.W.

    1979-01-01

    The definition of loads, loading combinations, and structural acceptance criteria used for the design and evaluation of BWR containments in the Unites States has become much more comprehensive over the past decade. The Mark I pressure suppression containment vessels were designed for a static design pressure, a design temperature, dead load and static equivalent earthquake. The current Mark III containments are being designed to accommodate many more loads such as safety relief valve discharge loads, and suppression pool hydrodynamic loadings associated with the steam condensation phenomena as well as pressure and temperature transients for a range of pipe break sizes. Consistent with the more comprehensive definition of loads and loading combinations, the ASME Code presently establishes structural acceptance criteria with different margins of safety by the definition of Service Level Assignments A, B, C and D. Acting in a responsible manner, United States utilities are currently evaluating and modifying existing containment vessels to account for the more detailed load definition and structural acceptance criteria. (orig.)

  18. Identification marking by means of laser peening

    Science.gov (United States)

    Hackel, Lloyd A.; Dane, C. Brent; Harris, Fritz

    2002-01-01

    The invention is a method and apparatus for marking components by inducing a shock wave on the surface that results in an indented (strained) layer and a residual compressive stress in the surface layer. One embodiment of the laser peenmarking system rapidly imprints, with single laser pulses, a complete identification code or three-dimensional pattern and leaves the surface in a state of deep residual compressive stress. A state of compressive stress in parts made of metal or other materials is highly desirable to make them resistant to fatigue failure and stress corrosion cracking. This process employs a laser peening system and beam spatial modulation hardware or imaging technology that can be setup to impress full three dimensional patterns into metal surfaces at the pulse rate of the laser, a rate that is at least an order of magnitude faster than competing marking technologies.

  19. Analysis of JSI TRIGA MARK II reactor physical parameters calculated with TRIPOLI and MCNP.

    Science.gov (United States)

    Henry, R; Tiselj, I; Snoj, L

    2015-03-01

    New computational model of the JSI TRIGA Mark II research reactor was built for TRIPOLI computer code and compared with existing MCNP code model. The same modelling assumptions were used in order to check the differences of the mathematical models of both Monte Carlo codes. Differences between the TRIPOLI and MCNP predictions of keff were up to 100pcm. Further validation was performed with analyses of the normalized reaction rates and computations of kinetic parameters for various core configurations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Topography measurements and applications in ballistics and tool mark identifications*

    Science.gov (United States)

    Vorburger, T V; Song, J; Petraco, N

    2016-01-01

    The application of surface topography measurement methods to the field of firearm and toolmark analysis is fairly new. The field has been boosted by the development of a number of competing optical methods, which has improved the speed and accuracy of surface topography acquisitions. We describe here some of these measurement methods as well as several analytical methods for assessing similarities and differences among pairs of surfaces. We also provide a few examples of research results to identify cartridge cases originating from the same firearm or tool marks produced by the same tool. Physical standards and issues of traceability are also discussed. PMID:27182440